About the Authors

Datsen George Wei

Affiliation Gilead Sciences, Foster City, California, United States of America

Vicki Chiang

Affiliation Gilead Sciences, Foster City, California, United States of America

Elizabeth Fyne

Affiliation Division of Infectious Diseases, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

Mini Balakrishnan

Affiliation Gilead Sciences, Foster City, California, United States of America

Tiffany Barnes

Affiliation Gilead Sciences, Foster City, California, United States of America

Michael Graupe

Affiliation Gilead Sciences, Foster City, California, United States of America

Joseph Hesselgesser

Affiliation Gilead Sciences, Foster City, California, United States of America

Alivelu Irrinki

Affiliation Gilead Sciences, Foster City, California, United States of America

Jeffrey P. Murry

Affiliation Gilead Sciences, Foster City, California, United States of America

George Stepan

Affiliation Gilead Sciences, Foster City, California, United States of America

Kirsten M. Stray

Affiliation Gilead Sciences, Foster City, California, United States of America

Angela Tsai

Affiliation Gilead Sciences, Foster City, California, United States of America

Helen Yu

Affiliation Gilead Sciences, Foster City, California, United States of America

Jonathan Spindler

Affiliation HIV Drug Resistance Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, United States of America

Mary Kearney

Affiliation HIV Drug Resistance Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, United States of America

Celsa A. Spina

Affiliation Department of Pathology, School of Medicine, University of California San Diego, La Jolla, California, United States of America

Deborah McMahon

Affiliation Division of Infectious Diseases, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

Jacob Lalezari

Affiliation Quest Clinical Research, San Francisco, California, United States of America

Derek Sloan

Affiliation Gilead Sciences, Foster City, California, United States of America

John Mellors

Affiliation Division of Infectious Diseases, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

Romas Geleziunas

Affiliation Gilead Sciences, Foster City, California, United States of America

Tomas Cihlar

tomas.cihlar@gilead.com

Affiliation Gilead Sciences, Foster City, California, United States of America

Competing Interests

DGW, VC, MB, TB, MG, JH, AI, JPM, GS, KMS, AT, HY, DS, RG, and TC are employees of Gilead Sciences, Inc. JM is a scientific advisor of Gilead Sciences, Inc. JL is a director of Quest Clinical Research that provided clinical specimens. EF, JS, MK, CAS, and DM have no competing interests. Part of the study was funded by Gilead Sciences, Inc. Employees of the company were involved in study design, data collection and analysis, and writing the manuscript. However, none of the therapeutics characterized in this study are products of Gilead Sciences, and studies were designed, executed, and objectively interpreted purely with a purpose to advance basic research in the field of HIV latency and cure. This does not alter our adherence to all PLOS Pathogens policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: DGW VC EF MB TB JH GS AT HY DS JM RG TC. Performed the experiments: DGW VC EF MB TB JH AI JPM GS AT HY DS JS. Analyzed the data: DGW VC EF MB JH AI JPM GS AT HY DS JM RG TC MK JS. Contributed reagents/materials/analysis tools: TB MG KMS CAS DM JL. Wrote the paper: DGW DS JM RG TC.