About the Authors

Bruno Correia

Contributed equally to this work with: Bruno Correia, Sofia A. Cerqueira

Affiliation Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal

Sofia A. Cerqueira

Contributed equally to this work with: Bruno Correia, Sofia A. Cerqueira

Affiliation Instituto de Microbiologia e Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal

Chantal Beauchemin

Affiliation Departments of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

Marta Pires de Miranda

Affiliation Instituto de Microbiologia e Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal

Shijun Li

Affiliation Departments of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

Rajesh Ponnusamy

Affiliation Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal

Lénia Rodrigues

Affiliation Instituto de Microbiologia e Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal

Thomas R. Schneider

Affiliation EMBL c/o DESY, Hamburg, Germany

Maria A. Carrondo

carrondo@itqb.unl.pt (MAC); kkaye@rics.bwh.harvard.edu (KMK); psimas@fm.ul.pt (JPS); mcvey@itqb.unl.pt (CEM)

Affiliation Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal

Kenneth M. Kaye

carrondo@itqb.unl.pt (MAC); kkaye@rics.bwh.harvard.edu (KMK); psimas@fm.ul.pt (JPS); mcvey@itqb.unl.pt (CEM)

Affiliation Departments of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

J. Pedro Simas

carrondo@itqb.unl.pt (MAC); kkaye@rics.bwh.harvard.edu (KMK); psimas@fm.ul.pt (JPS); mcvey@itqb.unl.pt (CEM)

Affiliation Instituto de Microbiologia e Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal

Colin E. McVey

carrondo@itqb.unl.pt (MAC); kkaye@rics.bwh.harvard.edu (KMK); psimas@fm.ul.pt (JPS); mcvey@itqb.unl.pt (CEM)

Affiliation Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CEM JPS KMK MAC. Performed the experiments: BC CEM MPdM SAC RP TRS SL CB LR. Analyzed the data: BC CEM MPdM LR RP CB SL. Wrote the paper: CEM MAC KMK JPS MPdM SL CB LR. X-ray synchrotron data collection: TRS.