About the Authors

Tomer Hertz

thertz@fhcrc.org

Affiliation Statistical Center for HIV Research and Prevention, Vaccine and Infectious Disease Division and the HIV Vaccine Trials Network, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

Hasan Ahmed

Affiliation Statistical Center for HIV Research and Prevention, Vaccine and Infectious Disease Division and the HIV Vaccine Trials Network, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

David P. Friedrich

Affiliation Statistical Center for HIV Research and Prevention, Vaccine and Infectious Disease Division and the HIV Vaccine Trials Network, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

Danilo R. Casimiro

Affiliation Merck Research Laboratories, West Point, Pennsylvania, United States of America

Steven G. Self

Affiliation Statistical Center for HIV Research and Prevention, Vaccine and Infectious Disease Division and the HIV Vaccine Trials Network, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

Lawrence Corey

Affiliation Statistical Center for HIV Research and Prevention, Vaccine and Infectious Disease Division and the HIV Vaccine Trials Network, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

M. Juliana McElrath

Affiliation Statistical Center for HIV Research and Prevention, Vaccine and Infectious Disease Division and the HIV Vaccine Trials Network, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

Susan Buchbinder

Affiliation HIV Research Section, San Francisco Department of Public Health, San Francisco, California, United States of America

Helen Horton

Affiliation Viral Vaccine Program, Seattle Biomedical Research Institute, Seattle, Washington, United States of America

Nicole Frahm

Affiliation Statistical Center for HIV Research and Prevention, Vaccine and Infectious Disease Division and the HIV Vaccine Trials Network, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

Michael N. Robertson

Affiliation Merck Research Laboratories, West Point, Pennsylvania, United States of America

Barney S. Graham

Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Peter Gilbert

Affiliation Statistical Center for HIV Research and Prevention, Vaccine and Infectious Disease Division and the HIV Vaccine Trials Network, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

Competing Interests

M. N. R. and D.R.C. are paid employees of Merck & Co., Inc. and own stock in Merck. This does not alter our adherence to all PLOS Pathogens policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: TH PG SGS. Performed the experiments: TH HA DPF HH NF. Analyzed the data: TH HA. Contributed reagents/materials/analysis tools: DRC BSG MNR NF HH DPF. Wrote the paper: TH HA LC DPF DRC HH MJM SB NF BSG PG.