About the Authors

Ana Villegas-Mendez

Current address: Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom

Affiliation Department of Immunology and Infection, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom

J. Brian de Souza

Affiliations Department of Immunology and Infection, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom, Department of Immunology and Molecular Pathology, University College London Medical School, London, United Kingdom

Seen-Wai Lavelle

Affiliation Department of Immunology and Infection, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom

Emily Gwyer Findlay

Current address: MRC Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom

Affiliation Department of Immunology and Infection, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom

Tovah N. Shaw

Current address: Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom

Affiliation Department of Immunology and Infection, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom

Nico van Rooijen

Affiliation Department of Molecular Cell Biology, VU Medical Center, Amsterdam, The Netherlands

Christiaan J. Saris

Affiliation Department of Inflammation Research, Amgen, Inc., Thousand Oaks, California, United States of America

Christopher A. Hunter

Affiliation Department of Pathobiology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Eleanor M. Riley

Affiliation Department of Immunology and Infection, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom

Kevin N. Couper

kevin.couper@manchester.ac.uk

Current address: Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom

Affiliation Department of Immunology and Infection, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom

Competing Interests

Christiaan J.M. Saris is a former employee of Amgen Inc. and owns stock and stock options in this company. Issued and pending Amgen patents on which he is a co-inventor are unrelated to the subject of this manuscript. This does not alter our adherence to all PLoS Pathogens policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: KNC AVM. Performed the experiments: AVM JBdS SWL EGF TNS KNC. Analyzed the data: AVM SWL KNC. Contributed reagents/materials/analysis tools: CJS CAH NvR. Wrote the paper: AVM EMR KNC.