Proteolytic Processing of Nlrp1b Is Required for Inflammasome Activity

Open Access

Peer-reviewed

Research Article

About the Authors

Bradley C. Frew

Vineet R. Joag

Jeremy Mogridge

* E-mail: jeremy.mogridge@utoronto.ca

Affiliation Department of Laboratory Medicine and Pathobiology, University of Toronto. Toronto, Ontario, Canada

The authors have declared that no competing interests exist.

Conceived and designed the experiments: BCF VRJ JM. Performed the experiments: BCF VRJ. Analyzed the data: BCF VRJ JM. Wrote the paper: BCF VRJ JM.

Transfection
Is the Subject Area "Transfection" applicable to this article?

Thanks for your feedback.
Immunoprecipitation
Is the Subject Area "Immunoprecipitation" applicable to this article?

Thanks for your feedback.
Proteases
Is the Subject Area "Proteases" applicable to this article?

Thanks for your feedback.
Inflammasomes
Is the Subject Area "Inflammasomes" applicable to this article?

Thanks for your feedback.
HT1080 cells
Is the Subject Area "HT1080 cells" applicable to this article?

Thanks for your feedback.
Immunoblotting
Is the Subject Area "Immunoblotting" applicable to this article?

Thanks for your feedback.
Polymerase chain reaction
Is the Subject Area "Polymerase chain reaction" applicable to this article?

Thanks for your feedback.
Substitution mutation
Is the Subject Area "Substitution mutation" applicable to this article?

Thanks for your feedback.