How “Humane” Is Your Endpoint?—Refining the Science-Driven Approach for Termination of Animal Studies of Chronic Infection

Nuno H. Franco; Margarida Correia-Neves; I. Anna S. Olsson

doi:10.1371/journal.ppat.1002399

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How “Humane” Is Your Endpoint?—Refining the Science-Driven Approach for Termination of Animal Studies of Chronic Infection

Nuno H. Franco ,

* E-mail: nfranco@ibmc.up.pt

Affiliation IBMC - Institute for Molecular and Cell Biology (Laboratory Animal Science Group), University of Porto, Porto, Portugal
⨯
Margarida Correia-Neves,

Affiliations Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal, ICVS/3B’s - PT Government Associate Laboratory, Braga/Guimarães, Portugal
⨯
I. Anna S. Olsson

Affiliation IBMC - Institute for Molecular and Cell Biology (Laboratory Animal Science Group), University of Porto, Porto, Portugal
⨯

How “Humane” Is Your Endpoint?—Refining the Science-Driven Approach for Termination of Animal Studies of Chronic Infection

Nuno H. Franco,
Margarida Correia-Neves,
I. Anna S. Olsson

Published: January 19, 2012
https://doi.org/10.1371/journal.ppat.1002399

About the Authors

Nuno H. Franco

* E-mail: nfranco@ibmc.up.pt

Affiliation IBMC - Institute for Molecular and Cell Biology (Laboratory Animal Science Group), University of Porto, Porto, Portugal

Margarida Correia-Neves

Affiliations Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal, ICVS/3B’s - PT Government Associate Laboratory, Braga/Guimarães, Portugal

I. Anna S. Olsson

Affiliation IBMC - Institute for Molecular and Cell Biology (Laboratory Animal Science Group), University of Porto, Porto, Portugal

Competing Interests

The authors have declared that no competing interests exist.

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Tuberculosis
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Animal welfare
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Euthanasia
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Mouse models
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Research ethics
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Animal models of infection
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Body weight
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