About the Authors

Stephen C. Graham

Affiliation Division of Structural Biology and Oxford Protein Production Facility, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

René Assenberg

Contributed equally to this work with: René Assenberg, Olivier Delmas

Affiliation Division of Structural Biology and Oxford Protein Production Facility, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

Olivier Delmas

Contributed equally to this work with: René Assenberg, Olivier Delmas

Affiliation UPRE Lyssavirus Dynamics and Host Adaptation, WHO Collaborating Centre for Reference and Research on Rabies, Institut Pasteur, Paris, France

Anil Verma

Affiliation Division of Structural Biology and Oxford Protein Production Facility, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

Alireza Gholami

Affiliation UPRE Lyssavirus Dynamics and Host Adaptation, WHO Collaborating Centre for Reference and Research on Rabies, Institut Pasteur, Paris, France

Chiraz Talbi

Affiliation UPRE Lyssavirus Dynamics and Host Adaptation, WHO Collaborating Centre for Reference and Research on Rabies, Institut Pasteur, Paris, France

Raymond J. Owens

Affiliation Division of Structural Biology and Oxford Protein Production Facility, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

David I. Stuart

Affiliation Division of Structural Biology and Oxford Protein Production Facility, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

Jonathan M. Grimes

jonathan@strubi.ox.ac.uk (JMG); hbourhy@pasteur.fr (HB)

Affiliation Division of Structural Biology and Oxford Protein Production Facility, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

Hervé Bourhy

jonathan@strubi.ox.ac.uk (JMG); hbourhy@pasteur.fr (HB)

Affiliation UPRE Lyssavirus Dynamics and Host Adaptation, WHO Collaborating Centre for Reference and Research on Rabies, Institut Pasteur, Paris, France

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Wrote the paper: SCG. Collected diffraction data, solved and refined the structures, and performed analytical gel filtration: SCG. Expressed, purified and crystallized LBV and VSVNJ M, and subcloned LBV M: RA. Cloned LBV and VSVNJ M: OD. Purified LBV M: AV. Cloned truncated LBV M: AG. Sequenced lyssavirus M genes: CT. Designed the experiments, interpreted the results and revised the manuscript: SCG RA OD AV AG CT RJO DIS JMG HB.