Novel Strategy to Prevent Otitis Media Caused by Colonizing Streptococcus pneumoniae

Jonathan A McCullers; Åsa Karlström; Amy R Iverson; Jutta M Loeffler; Vincent A Fischetti

doi:10.1371/journal.ppat.0030028

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Novel Strategy to Prevent Otitis Media Caused by Colonizing Streptococcus pneumoniae

Jonathan A McCullers ,

*To whom correspondence should be addressed. E-mail: jon.mccullers@stjude.org
⨯
Åsa Karlström,
Amy R Iverson,
Jutta M Loeffler,
Vincent A Fischetti

Novel Strategy to Prevent Otitis Media Caused by Colonizing Streptococcus pneumoniae

Jonathan A McCullers,
Åsa Karlström,
Amy R Iverson,
Jutta M Loeffler,
Vincent A Fischetti

Published: March 23, 2007
https://doi.org/10.1371/journal.ppat.0030028

About the Authors

Jonathan A McCullers: *To whom correspondence should be addressed. E-mail: jon.mccullers@stjude.org
Åsa Karlström
Amy R Iverson
Jutta M Loeffler
Vincent A Fischetti

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

JAM and VAF conceived and designed the experiments and wrote the paper. ARI and JML developed the pneumococcal strain and bacteriophage lytic enzyme, which were used in animal experiments conducted by JAM and AK.

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Mouse models
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Pneumococcus
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Bacterial pathogens
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Otitis media
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