Human Retroviral Host Restriction Factors APOBEC3G and APOBEC3F Localize to mRNA Processing Bodies

Michael J Wichroski; G. Brett Robb; Tariq M Rana

doi:10.1371/journal.ppat.0020041

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Open Access

Peer-reviewed

Research Article

Human Retroviral Host Restriction Factors APOBEC3G and APOBEC3F Localize to mRNA Processing Bodies

Michael J Wichroski,

Affiliation Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
G. Brett Robb,

Affiliation Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Tariq M Rana

*To whom correspondence should be addressed. E-mail: tariq.rana@umassmed.edu

Affiliation Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯

Human Retroviral Host Restriction Factors APOBEC3G and APOBEC3F Localize to mRNA Processing Bodies

Michael J Wichroski,
G. Brett Robb,
Tariq M Rana

Published: May 12, 2006
https://doi.org/10.1371/journal.ppat.0020041

About the Authors

Michael J Wichroski

Affiliation Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

G. Brett Robb

Affiliation Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

Tariq M Rana

*To whom correspondence should be addressed. E-mail: tariq.rana@umassmed.edu

Affiliation Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

MJW and TMR conceived and designed the experiments. MJW and GBR performed the experiments. MJW, GBR, and TMR analyzed the data. GBR contributed reagents/materials/analysis tools. MJW and TMR wrote the paper.

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HIV-1
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293T cells
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Viral replication
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Immunoprecipitation
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Immunostaining
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Messenger RNA
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T cells
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DNA replication
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