About the Authors

Ke Hu

Affiliation Department of Cell Biology, Scripps Research Institute, La Jolla, California, United States of America

Jeff Johnson

Affiliation Department of Cell Biology, Scripps Research Institute, La Jolla, California, United States of America

Laurence Florens

Affiliation The Stowers Institute for Medical Research, Kansas City, Missouri, United States of America

Martin Fraunholz

Affiliation Institute of Microbiology, E.-M.-Arndt University, Greifswald, Germany

Sapna Suravajjala

Affiliation Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Camille DiLullo

Affiliation Department of Anatomy, Philadelphia College of Osteopathic Medicine, Philadelphia, Pennsylvania, United States of America

John Yates

Affiliation Department of Cell Biology, Scripps Research Institute, La Jolla, California, United States of America

David S Roos

Affiliation Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

John M Murray

To whom correspondence should be addressed. E-mail: murray@cellbio.med.upenn.edu

Affiliation Department of Cell & Developmental Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

KH and JMM conceived and designed the experiments. KH, JJ, LF, SS, CD, and JMM performed the experiments. KH, JJ, LF, and JMM analyzed the data. KH, JY, DSR, and JMM contributed reagents/materials/analysis tools. MF and DSR suggested an important experiment. KH and JMM wrote the paper.