/*!
 * Copyright (c) 2017 Public Library of Science
 *
 * Permission is hereby granted, free of charge, to any person obtaining a
 * copy of this software and associated documentation files (the "Software"),
 * to deal in the Software without restriction, including without limitation
 * the rights to use, copy, modify, merge, publish, distribute, sublicense,
 * and/or sell copies of the Software, and to permit persons to whom the
 * Software is furnished to do so, subject to the following conditions:
 *
 * The above copyright notice and this permission notice shall be included in
 * all copies or substantial portions of the Software.
 *
 * THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
 * IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
 * FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
 * THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
 * LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
 * FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
 * DEALINGS IN THE SOFTWARE.
 *//*!
 * Copyright (c) 2017 Public Library of Science
 *
 * Permission is hereby granted, free of charge, to any person obtaining a
 * copy of this software and associated documentation files (the "Software"),
 * to deal in the Software without restriction, including without limitation
 * the rights to use, copy, modify, merge, publish, distribute, sublicense,
 * and/or sell copies of the Software, and to permit persons to whom the
 * Software is furnished to do so, subject to the following conditions:
 *
 * The above copyright notice and this permission notice shall be included in
 * all copies or substantial portions of the Software.
 *
 * THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
 * IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
 * FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
 * THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
 * LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
 * FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
 * DEALINGS IN THE SOFTWARE.
 *//*!
 * Copyright (c) 2017 Public Library of Science
 *
 * Permission is hereby granted, free of charge, to any person obtaining a
 * copy of this software and associated documentation files (the "Software"),
 * to deal in the Software without restriction, including without limitation
 * the rights to use, copy, modify, merge, publish, distribute, sublicense,
 * and/or sell copies of the Software, and to permit persons to whom the
 * Software is furnished to do so, subject to the following conditions:
 *
 * The above copyright notice and this permission notice shall be included in
 * all copies or substantial portions of the Software.
 *
 * THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
 * IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
 * FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
 * THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
 * LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
 * FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
 * DEALINGS IN THE SOFTWARE.
 *//*!
 * Copyright (c) 2017 Public Library of Science
 *
 * Permission is hereby granted, free of charge, to any person obtaining a
 * copy of this software and associated documentation files (the "Software"),
 * to deal in the Software without restriction, including without limitation
 * the rights to use, copy, modify, merge, publish, distribute, sublicense,
 * and/or sell copies of the Software, and to permit persons to whom the
 * Software is furnished to do so, subject to the following conditions:
 *
 * The above copyright notice and this permission notice shall be included in
 * all copies or substantial portions of the Software.
 *
 * THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
 * IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
 * FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
 * THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
 * LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
 * FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
 * DEALINGS IN THE SOFTWARE.
 */meta.foundation-version{font-family:"/5.5.3/"}meta.foundation-mq-small{font-family:"/only screen/";width:0}meta.foundation-mq-small-only{font-family:"/only screen and (max-width: 90em)/";width:0}meta.foundation-mq-medium{font-family:"/only screen and (min-width:0em)/";width:0}meta.foundation-mq-medium-only{font-family:"/only screen and (min-width:0em) and (max-width:90em)/";width:0}meta.foundation-mq-large{font-family:"/only screen and (min-width:64.063em)/";width:64.063em}meta.foundation-mq-large-only{font-family:"/only screen and (min-width:64.063em) and (max-width:90em)/";width:64.063em}meta.foundation-mq-xlarge{font-family:"/only screen and (min-width:90.063em)/";width:90.063em}meta.foundation-mq-xlarge-only{font-family:"/only screen and (min-width:90.063em) and (max-width:120em)/";width:90.063em}meta.foundation-mq-xxlarge{font-family:"/only screen and (min-width:120.0625em)/";width:120.0625em}meta.foundation-data-attribute-namespace{font-family:false}html,body{height:100%}*,*:before,*:after{-webkit-box-sizing:border-box;-moz-box-sizing:border-box;box-sizing:border-box}html,body{font-size:100%}body{background:#fff;color:#333;cursor:auto;font-family:"arial";font-style:normal;font-weight:normal;line-height:120%;margin:0;padding:0;position:relative}a:hover{cursor:pointer}img{max-width:100%;height:auto}img{-ms-interpolation-mode:bicubic}#map_canvas img,#map_canvas embed,#map_canvas object,.map_canvas img,.map_canvas embed,.map_canvas object,.mqa-display img,.mqa-display embed,.mqa-display object{max-width:none!important}.left{float:left!important}.right,.nav .nav-user,.top-bar-section ul.nav-elements,.top-bar-section .head-search{float:right!important}.clearfix:before,.clearfix:after{content:" ";display:table}.clearfix:after{clear:both}.hide{display:none}.invisible{visibility:hidden}.antialiased{-webkit-font-smoothing:antialiased;-moz-osx-font-smoothing:grayscale}img{display:inline-block;vertical-align:middle}textarea{height:auto;min-height:50px}select{width:100%}[class*="block-grid-"]{display:block;padding:0;margin:0}[class*="block-grid-"]:before,[class*="block-grid-"]:after{content:" ";display:table}[class*="block-grid-"]:after{clear:both}[class*="block-grid-"]>li{display:block;float:left;height:auto;padding:0 10px 20px}@media only screen{.small-block-grid-1>li{list-style:none;width:100%}.small-block-grid-1>li:nth-of-type(1n){clear:none}.small-block-grid-1>li:nth-of-type(1n+1){clear:both}.small-block-grid-1>li:nth-of-type(1n){padding-left:0;padding-right:0}.small-block-grid-2>li{list-style:none;width:50%}.small-block-grid-2>li:nth-of-type(1n){clear:none}.small-block-grid-2>li:nth-of-type(2n+1){clear:both}.small-block-grid-2>li:nth-of-type(2n+1){padding-left:0;padding-right:10px}.small-block-grid-2>li:nth-of-type(2n){padding-left:10px;padding-right:0}.small-block-grid-3>li{list-style:none;width:33.33333%}.small-block-grid-3>li:nth-of-type(1n){clear:none}.small-block-grid-3>li:nth-of-type(3n+1){clear:both}.small-block-grid-3>li:nth-of-type(3n+1){padding-left:0;padding-right:13.33333px}.small-block-grid-3>li:nth-of-type(3n+2){padding-left:6.66667px;padding-right:6.66667px}.small-block-grid-3>li:nth-of-type(3n){padding-left:13.33333px;padding-right:0}.small-block-grid-4>li{list-style:none;width:25%}.small-block-grid-4>li:nth-of-type(1n){clear:none}.small-block-grid-4>li:nth-of-type(4n+1){clear:both}.small-block-grid-4>li:nth-of-type(4n+1){padding-left:0;padding-right:15px}.small-block-grid-4>li:nth-of-type(4n+2){padding-left:5px;padding-right:10px}.small-block-grid-4>li:nth-of-type(4n+3){padding-left:10px;padding-right:5px}.small-block-grid-4>li:nth-of-type(4n){padding-left:15px;padding-right:0}.small-block-grid-5>li{list-style:none;width:20%}.small-block-grid-5>li:nth-of-type(1n){clear:none}.small-block-grid-5>li:nth-of-type(5n+1){clear:both}.small-block-grid-5>li:nth-of-type(5n+1){padding-left:0;padding-right:16px}.small-block-grid-5>li:nth-of-type(5n+2){padding-left:4px;padding-right:12px}.small-block-grid-5>li:nth-of-type(5n+3){padding-left:8px;padding-right:8px}.small-block-grid-5>li:nth-of-type(5n+4){padding-left:12px;padding-right:4px}.small-block-grid-5>li:nth-of-type(5n){padding-left:16px;padding-right:0}.small-block-grid-6>li{list-style:none;width:16.66667%}.small-block-grid-6>li:nth-of-type(1n){clear:none}.small-block-grid-6>li:nth-of-type(6n+1){clear:both}.small-block-grid-6>li:nth-of-type(6n+1){padding-left:0;padding-right:16.66667px}.small-block-grid-6>li:nth-of-type(6n+2){padding-left:3.33333px;padding-right:13.33333px}.small-block-grid-6>li:nth-of-type(6n+3){padding-left:6.66667px;padding-right:10px}.small-block-grid-6>li:nth-of-type(6n+4){padding-left:10px;padding-right:6.66667px}.small-block-grid-6>li:nth-of-type(6n+5){padding-left:13.33333px;padding-right:3.33333px}.small-block-grid-6>li:nth-of-type(6n){padding-left:16.66667px;padding-right:0}.small-block-grid-7>li{list-style:none;width:14.28571%}.small-block-grid-7>li:nth-of-type(1n){clear:none}.small-block-grid-7>li:nth-of-type(7n+1){clear:both}.small-block-grid-7>li:nth-of-type(7n+1){padding-left:0;padding-right:17.14286px}.small-block-grid-7>li:nth-of-type(7n+2){padding-left:2.85714px;padding-right:14.28571px}.small-block-grid-7>li:nth-of-type(7n+3){padding-left:5.71429px;padding-right:11.42857px}.small-block-grid-7>li:nth-of-type(7n+4){padding-left:8.57143px;padding-right:8.57143px}.small-block-grid-7>li:nth-of-type(7n+5){padding-left:11.42857px;padding-right:5.71429px}.small-block-grid-7>li:nth-of-type(7n+6){padding-left:14.28571px;padding-right:2.85714px}.small-block-grid-7>li:nth-of-type(7n){padding-left:17.14286px;padding-right:0}.small-block-grid-8>li{list-style:none;width:12.5%}.small-block-grid-8>li:nth-of-type(1n){clear:none}.small-block-grid-8>li:nth-of-type(8n+1){clear:both}.small-block-grid-8>li:nth-of-type(8n+1){padding-left:0;padding-right:17.5px}.small-block-grid-8>li:nth-of-type(8n+2){padding-left:2.5px;padding-right:15px}.small-block-grid-8>li:nth-of-type(8n+3){padding-left:5px;padding-right:12.5px}.small-block-grid-8>li:nth-of-type(8n+4){padding-left:7.5px;padding-right:10px}.small-block-grid-8>li:nth-of-type(8n+5){padding-left:10px;padding-right:7.5px}.small-block-grid-8>li:nth-of-type(8n+6){padding-left:12.5px;padding-right:5px}.small-block-grid-8>li:nth-of-type(8n+7){padding-left:15px;padding-right:2.5px}.small-block-grid-8>li:nth-of-type(8n){padding-left:17.5px;padding-right:0}.small-block-grid-9>li{list-style:none;width:11.11111%}.small-block-grid-9>li:nth-of-type(1n){clear:none}.small-block-grid-9>li:nth-of-type(9n+1){clear:both}.small-block-grid-9>li:nth-of-type(9n+1){padding-left:0;padding-right:17.77778px}.small-block-grid-9>li:nth-of-type(9n+2){padding-left:2.22222px;padding-right:15.55556px}.small-block-grid-9>li:nth-of-type(9n+3){padding-left:4.44444px;padding-right:13.33333px}.small-block-grid-9>li:nth-of-type(9n+4){padding-left:6.66667px;padding-right:11.11111px}.small-block-grid-9>li:nth-of-type(9n+5){padding-left:8.88889px;padding-right:8.88889px}.small-block-grid-9>li:nth-of-type(9n+6){padding-left:11.11111px;padding-right:6.66667px}.small-block-grid-9>li:nth-of-type(9n+7){padding-left:13.33333px;padding-right:4.44444px}.small-block-grid-9>li:nth-of-type(9n+8){padding-left:15.55556px;padding-right:2.22222px}.small-block-grid-9>li:nth-of-type(9n){padding-left:17.77778px;padding-right:0}.small-block-grid-10>li{list-style:none;width:10%}.small-block-grid-10>li:nth-of-type(1n){clear:none}.small-block-grid-10>li:nth-of-type(10n+1){clear:both}.small-block-grid-10>li:nth-of-type(10n+1){padding-left:0;padding-right:18px}.small-block-grid-10>li:nth-of-type(10n+2){padding-left:2px;padding-right:16px}.small-block-grid-10>li:nth-of-type(10n+3){padding-left:4px;padding-right:14px}.small-block-grid-10>li:nth-of-type(10n+4){padding-left:6px;padding-right:12px}.small-block-grid-10>li:nth-of-type(10n+5){padding-left:8px;padding-right:10px}.small-block-grid-10>li:nth-of-type(10n+6){padding-left:10px;padding-right:8px}.small-block-grid-10>li:nth-of-type(10n+7){padding-left:12px;padding-right:6px}.small-block-grid-10>li:nth-of-type(10n+8){padding-left:14px;padding-right:4px}.small-block-grid-10>li:nth-of-type(10n+9){padding-left:16px;padding-right:2px}.small-block-grid-10>li:nth-of-type(10n){padding-left:18px;padding-right:0}.small-block-grid-11>li{list-style:none;width:9.09091%}.small-block-grid-11>li:nth-of-type(1n){clear:none}.small-block-grid-11>li:nth-of-type(11n+1){clear:both}.small-block-grid-11>li:nth-of-type(11n+1){padding-left:0;padding-right:18.18182px}.small-block-grid-11>li:nth-of-type(11n+2){padding-left:1.81818px;padding-right:16.36364px}.small-block-grid-11>li:nth-of-type(11n+3){padding-left:3.63636px;padding-right:14.54545px}.small-block-grid-11>li:nth-of-type(11n+4){padding-left:5.45455px;padding-right:12.72727px}.small-block-grid-11>li:nth-of-type(11n+5){padding-left:7.27273px;padding-right:10.90909px}.small-block-grid-11>li:nth-of-type(11n+6){padding-left:9.09091px;padding-right:9.09091px}.small-block-grid-11>li:nth-of-type(11n+7){padding-left:10.90909px;padding-right:7.27273px}.small-block-grid-11>li:nth-of-type(11n+8){padding-left:12.72727px;padding-right:5.45455px}.small-block-grid-11>li:nth-of-type(11n+9){padding-left:14.54545px;padding-right:3.63636px}.small-block-grid-11>li:nth-of-type(11n+10){padding-left:16.36364px;padding-right:1.81818px}.small-block-grid-11>li:nth-of-type(11n){padding-left:18.18182px;padding-right:0}.small-block-grid-12>li{list-style:none;width:8.33333%}.small-block-grid-12>li:nth-of-type(1n){clear:none}.small-block-grid-12>li:nth-of-type(12n+1){clear:both}.small-block-grid-12>li:nth-of-type(12n+1){padding-left:0;padding-right:18.33333px}.small-block-grid-12>li:nth-of-type(12n+2){padding-left:1.66667px;padding-right:16.66667px}.small-block-grid-12>li:nth-of-type(12n+3){padding-left:3.33333px;padding-right:15px}.small-block-grid-12>li:nth-of-type(12n+4){padding-left:5px;padding-right:13.33333px}.small-block-grid-12>li:nth-of-type(12n+5){padding-left:6.66667px;padding-right:11.66667px}.small-block-grid-12>li:nth-of-type(12n+6){padding-left:8.33333px;padding-right:10px}.small-block-grid-12>li:nth-of-type(12n+7){padding-left:10px;padding-right:8.33333px}.small-block-grid-12>li:nth-of-type(12n+8){padding-left:11.66667px;padding-right:6.66667px}.small-block-grid-12>li:nth-of-type(12n+9){padding-left:13.33333px;padding-right:5px}.small-block-grid-12>li:nth-of-type(12n+10){padding-left:15px;padding-right:3.33333px}.small-block-grid-12>li:nth-of-type(12n+11){padding-left:16.66667px;padding-right:1.66667px}.small-block-grid-12>li:nth-of-type(12n){padding-left:18.33333px;padding-right:0}}@media only screen and (min-width:0){.medium-block-grid-1>li{list-style:none;width:100%}.medium-block-grid-1>li:nth-of-type(1n){clear:none}.medium-block-grid-1>li:nth-of-type(1n+1){clear:both}.medium-block-grid-1>li:nth-of-type(1n){padding-left:0;padding-right:0}.medium-block-grid-2>li{list-style:none;width:50%}.medium-block-grid-2>li:nth-of-type(1n){clear:none}.medium-block-grid-2>li:nth-of-type(2n+1){clear:both}.medium-block-grid-2>li:nth-of-type(2n+1){padding-left:0;padding-right:10px}.medium-block-grid-2>li:nth-of-type(2n){padding-left:10px;padding-right:0}.medium-block-grid-3>li{list-style:none;width:33.33333%}.medium-block-grid-3>li:nth-of-type(1n){clear:none}.medium-block-grid-3>li:nth-of-type(3n+1){clear:both}.medium-block-grid-3>li:nth-of-type(3n+1){padding-left:0;padding-right:13.33333px}.medium-block-grid-3>li:nth-of-type(3n+2){padding-left:6.66667px;padding-right:6.66667px}.medium-block-grid-3>li:nth-of-type(3n){padding-left:13.33333px;padding-right:0}.medium-block-grid-4>li{list-style:none;width:25%}.medium-block-grid-4>li:nth-of-type(1n){clear:none}.medium-block-grid-4>li:nth-of-type(4n+1){clear:both}.medium-block-grid-4>li:nth-of-type(4n+1){padding-left:0;padding-right:15px}.medium-block-grid-4>li:nth-of-type(4n+2){padding-left:5px;padding-right:10px}.medium-block-grid-4>li:nth-of-type(4n+3){padding-left:10px;padding-right:5px}.medium-block-grid-4>li:nth-of-type(4n){padding-left:15px;padding-right:0}.medium-block-grid-5>li{list-style:none;width:20%}.medium-block-grid-5>li:nth-of-type(1n){clear:none}.medium-block-grid-5>li:nth-of-type(5n+1){clear:both}.medium-block-grid-5>li:nth-of-type(5n+1){padding-left:0;padding-right:16px}.medium-block-grid-5>li:nth-of-type(5n+2){padding-left:4px;padding-right:12px}.medium-block-grid-5>li:nth-of-type(5n+3){padding-left:8px;padding-right:8px}.medium-block-grid-5>li:nth-of-type(5n+4){padding-left:12px;padding-right:4px}.medium-block-grid-5>li:nth-of-type(5n){padding-left:16px;padding-right:0}.medium-block-grid-6>li{list-style:none;width:16.66667%}.medium-block-grid-6>li:nth-of-type(1n){clear:none}.medium-block-grid-6>li:nth-of-type(6n+1){clear:both}.medium-block-grid-6>li:nth-of-type(6n+1){padding-left:0;padding-right:16.66667px}.medium-block-grid-6>li:nth-of-type(6n+2){padding-left:3.33333px;padding-right:13.33333px}.medium-block-grid-6>li:nth-of-type(6n+3){padding-left:6.66667px;padding-right:10px}.medium-block-grid-6>li:nth-of-type(6n+4){padding-left:10px;padding-right:6.66667px}.medium-block-grid-6>li:nth-of-type(6n+5){padding-left:13.33333px;padding-right:3.33333px}.medium-block-grid-6>li:nth-of-type(6n){padding-left:16.66667px;padding-right:0}.medium-block-grid-7>li{list-style:none;width:14.28571%}.medium-block-grid-7>li:nth-of-type(1n){clear:none}.medium-block-grid-7>li:nth-of-type(7n+1){clear:both}.medium-block-grid-7>li:nth-of-type(7n+1){padding-left:0;padding-right:17.14286px}.medium-block-grid-7>li:nth-of-type(7n+2){padding-left:2.85714px;padding-right:14.28571px}.medium-block-grid-7>li:nth-of-type(7n+3){padding-left:5.71429px;padding-right:11.42857px}.medium-block-grid-7>li:nth-of-type(7n+4){padding-left:8.57143px;padding-right:8.57143px}.medium-block-grid-7>li:nth-of-type(7n+5){padding-left:11.42857px;padding-right:5.71429px}.medium-block-grid-7>li:nth-of-type(7n+6){padding-left:14.28571px;padding-right:2.85714px}.medium-block-grid-7>li:nth-of-type(7n){padding-left:17.14286px;padding-right:0}.medium-block-grid-8>li{list-style:none;width:12.5%}.medium-block-grid-8>li:nth-of-type(1n){clear:none}.medium-block-grid-8>li:nth-of-type(8n+1){clear:both}.medium-block-grid-8>li:nth-of-type(8n+1){padding-left:0;padding-right:17.5px}.medium-block-grid-8>li:nth-of-type(8n+2){padding-left:2.5px;padding-right:15px}.medium-block-grid-8>li:nth-of-type(8n+3){padding-left:5px;padding-right:12.5px}.medium-block-grid-8>li:nth-of-type(8n+4){padding-left:7.5px;padding-right:10px}.medium-block-grid-8>li:nth-of-type(8n+5){padding-left:10px;padding-right:7.5px}.medium-block-grid-8>li:nth-of-type(8n+6){padding-left:12.5px;padding-right:5px}.medium-block-grid-8>li:nth-of-type(8n+7){padding-left:15px;padding-right:2.5px}.medium-block-grid-8>li:nth-of-type(8n){padding-left:17.5px;padding-right:0}.medium-block-grid-9>li{list-style:none;width:11.11111%}.medium-block-grid-9>li:nth-of-type(1n){clear:none}.medium-block-grid-9>li:nth-of-type(9n+1){clear:both}.medium-block-grid-9>li:nth-of-type(9n+1){padding-left:0;padding-right:17.77778px}.medium-block-grid-9>li:nth-of-type(9n+2){padding-left:2.22222px;padding-right:15.55556px}.medium-block-grid-9>li:nth-of-type(9n+3){padding-left:4.44444px;padding-right:13.33333px}.medium-block-grid-9>li:nth-of-type(9n+4){padding-left:6.66667px;padding-right:11.11111px}.medium-block-grid-9>li:nth-of-type(9n+5){padding-left:8.88889px;padding-right:8.88889px}.medium-block-grid-9>li:nth-of-type(9n+6){padding-left:11.11111px;padding-right:6.66667px}.medium-block-grid-9>li:nth-of-type(9n+7){padding-left:13.33333px;padding-right:4.44444px}.medium-block-grid-9>li:nth-of-type(9n+8){padding-left:15.55556px;padding-right:2.22222px}.medium-block-grid-9>li:nth-of-type(9n){padding-left:17.77778px;padding-right:0}.medium-block-grid-10>li{list-style:none;width:10%}.medium-block-grid-10>li:nth-of-type(1n){clear:none}.medium-block-grid-10>li:nth-of-type(10n+1){clear:both}.medium-block-grid-10>li:nth-of-type(10n+1){padding-left:0;padding-right:18px}.medium-block-grid-10>li:nth-of-type(10n+2){padding-left:2px;padding-right:16px}.medium-block-grid-10>li:nth-of-type(10n+3){padding-left:4px;padding-right:14px}.medium-block-grid-10>li:nth-of-type(10n+4){padding-left:6px;padding-right:12px}.medium-block-grid-10>li:nth-of-type(10n+5){padding-left:8px;padding-right:10px}.medium-block-grid-10>li:nth-of-type(10n+6){padding-left:10px;padding-right:8px}.medium-block-grid-10>li:nth-of-type(10n+7){padding-left:12px;padding-right:6px}.medium-block-grid-10>li:nth-of-type(10n+8){padding-left:14px;padding-right:4px}.medium-block-grid-10>li:nth-of-type(10n+9){padding-left:16px;padding-right:2px}.medium-block-grid-10>li:nth-of-type(10n){padding-left:18px;padding-right:0}.medium-block-grid-11>li{list-style:none;width:9.09091%}.medium-block-grid-11>li:nth-of-type(1n){clear:none}.medium-block-grid-11>li:nth-of-type(11n+1){clear:both}.medium-block-grid-11>li:nth-of-type(11n+1){padding-left:0;padding-right:18.18182px}.medium-block-grid-11>li:nth-of-type(11n+2){padding-left:1.81818px;padding-right:16.36364px}.medium-block-grid-11>li:nth-of-type(11n+3){padding-left:3.63636px;padding-right:14.54545px}.medium-block-grid-11>li:nth-of-type(11n+4){padding-left:5.45455px;padding-right:12.72727px}.medium-block-grid-11>li:nth-of-type(11n+5){padding-left:7.27273px;padding-right:10.90909px}.medium-block-grid-11>li:nth-of-type(11n+6){padding-left:9.09091px;padding-right:9.09091px}.medium-block-grid-11>li:nth-of-type(11n+7){padding-left:10.90909px;padding-right:7.27273px}.medium-block-grid-11>li:nth-of-type(11n+8){padding-left:12.72727px;padding-right:5.45455px}.medium-block-grid-11>li:nth-of-type(11n+9){padding-left:14.54545px;padding-right:3.63636px}.medium-block-grid-11>li:nth-of-type(11n+10){padding-left:16.36364px;padding-right:1.81818px}.medium-block-grid-11>li:nth-of-type(11n){padding-left:18.18182px;padding-right:0}.medium-block-grid-12>li{list-style:none;width:8.33333%}.medium-block-grid-12>li:nth-of-type(1n){clear:none}.medium-block-grid-12>li:nth-of-type(12n+1){clear:both}.medium-block-grid-12>li:nth-of-type(12n+1){padding-left:0;padding-right:18.33333px}.medium-block-grid-12>li:nth-of-type(12n+2){padding-left:1.66667px;padding-right:16.66667px}.medium-block-grid-12>li:nth-of-type(12n+3){padding-left:3.33333px;padding-right:15px}.medium-block-grid-12>li:nth-of-type(12n+4){padding-left:5px;padding-right:13.33333px}.medium-block-grid-12>li:nth-of-type(12n+5){padding-left:6.66667px;padding-right:11.66667px}.medium-block-grid-12>li:nth-of-type(12n+6){padding-left:8.33333px;padding-right:10px}.medium-block-grid-12>li:nth-of-type(12n+7){padding-left:10px;padding-right:8.33333px}.medium-block-grid-12>li:nth-of-type(12n+8){padding-left:11.66667px;padding-right:6.66667px}.medium-block-grid-12>li:nth-of-type(12n+9){padding-left:13.33333px;padding-right:5px}.medium-block-grid-12>li:nth-of-type(12n+10){padding-left:15px;padding-right:3.33333px}.medium-block-grid-12>li:nth-of-type(12n+11){padding-left:16.66667px;padding-right:1.66667px}.medium-block-grid-12>li:nth-of-type(12n){padding-left:18.33333px;padding-right:0}}@media only screen and (min-width:64.063em){.large-block-grid-1>li{list-style:none;width:100%}.large-block-grid-1>li:nth-of-type(1n){clear:none}.large-block-grid-1>li:nth-of-type(1n+1){clear:both}.large-block-grid-1>li:nth-of-type(1n){padding-left:0;padding-right:0}.large-block-grid-2>li{list-style:none;width:50%}.large-block-grid-2>li:nth-of-type(1n){clear:none}.large-block-grid-2>li:nth-of-type(2n+1){clear:both}.large-block-grid-2>li:nth-of-type(2n+1){padding-left:0;padding-right:10px}.large-block-grid-2>li:nth-of-type(2n){padding-left:10px;padding-right:0}.large-block-grid-3>li{list-style:none;width:33.33333%}.large-block-grid-3>li:nth-of-type(1n){clear:none}.large-block-grid-3>li:nth-of-type(3n+1){clear:both}.large-block-grid-3>li:nth-of-type(3n+1){padding-left:0;padding-right:13.33333px}.large-block-grid-3>li:nth-of-type(3n+2){padding-left:6.66667px;padding-right:6.66667px}.large-block-grid-3>li:nth-of-type(3n){padding-left:13.33333px;padding-right:0}.large-block-grid-4>li{list-style:none;width:25%}.large-block-grid-4>li:nth-of-type(1n){clear:none}.large-block-grid-4>li:nth-of-type(4n+1){clear:both}.large-block-grid-4>li:nth-of-type(4n+1){padding-left:0;padding-right:15px}.large-block-grid-4>li:nth-of-type(4n+2){padding-left:5px;padding-right:10px}.large-block-grid-4>li:nth-of-type(4n+3){padding-left:10px;padding-right:5px}.large-block-grid-4>li:nth-of-type(4n){padding-left:15px;padding-right:0}.large-block-grid-5>li{list-style:none;width:20%}.large-block-grid-5>li:nth-of-type(1n){clear:none}.large-block-grid-5>li:nth-of-type(5n+1){clear:both}.large-block-grid-5>li:nth-of-type(5n+1){padding-left:0;padding-right:16px}.large-block-grid-5>li:nth-of-type(5n+2){padding-left:4px;padding-right:12px}.large-block-grid-5>li:nth-of-type(5n+3){padding-left:8px;padding-right:8px}.large-block-grid-5>li:nth-of-type(5n+4){padding-left:12px;padding-right:4px}.large-block-grid-5>li:nth-of-type(5n){padding-left:16px;padding-right:0}.large-block-grid-6>li{list-style:none;width:16.66667%}.large-block-grid-6>li:nth-of-type(1n){clear:none}.large-block-grid-6>li:nth-of-type(6n+1){clear:both}.large-block-grid-6>li:nth-of-type(6n+1){padding-left:0;padding-right:16.66667px}.large-block-grid-6>li:nth-of-type(6n+2){padding-left:3.33333px;padding-right:13.33333px}.large-block-grid-6>li:nth-of-type(6n+3){padding-left:6.66667px;padding-right:10px}.large-block-grid-6>li:nth-of-type(6n+4){padding-left:10px;padding-right:6.66667px}.large-block-grid-6>li:nth-of-type(6n+5){padding-left:13.33333px;padding-right:3.33333px}.large-block-grid-6>li:nth-of-type(6n){padding-left:16.66667px;padding-right:0}.large-block-grid-7>li{list-style:none;width:14.28571%}.large-block-grid-7>li:nth-of-type(1n){clear:none}.large-block-grid-7>li:nth-of-type(7n+1){clear:both}.large-block-grid-7>li:nth-of-type(7n+1){padding-left:0;padding-right:17.14286px}.large-block-grid-7>li:nth-of-type(7n+2){padding-left:2.85714px;padding-right:14.28571px}.large-block-grid-7>li:nth-of-type(7n+3){padding-left:5.71429px;padding-right:11.42857px}.large-block-grid-7>li:nth-of-type(7n+4){padding-left:8.57143px;padding-right:8.57143px}.large-block-grid-7>li:nth-of-type(7n+5){padding-left:11.42857px;padding-right:5.71429px}.large-block-grid-7>li:nth-of-type(7n+6){padding-left:14.28571px;padding-right:2.85714px}.large-block-grid-7>li:nth-of-type(7n){padding-left:17.14286px;padding-right:0}.large-block-grid-8>li{list-style:none;width:12.5%}.large-block-grid-8>li:nth-of-type(1n){clear:none}.large-block-grid-8>li:nth-of-type(8n+1){clear:both}.large-block-grid-8>li:nth-of-type(8n+1){padding-left:0;padding-right:17.5px}.large-block-grid-8>li:nth-of-type(8n+2){padding-left:2.5px;padding-right:15px}.large-block-grid-8>li:nth-of-type(8n+3){padding-left:5px;padding-right:12.5px}.large-block-grid-8>li:nth-of-type(8n+4){padding-left:7.5px;padding-right:10px}.large-block-grid-8>li:nth-of-type(8n+5){padding-left:10px;padding-right:7.5px}.large-block-grid-8>li:nth-of-type(8n+6){padding-left:12.5px;padding-right:5px}.large-block-grid-8>li:nth-of-type(8n+7){padding-left:15px;padding-right:2.5px}.large-block-grid-8>li:nth-of-type(8n){padding-left:17.5px;padding-right:0}.large-block-grid-9>li{list-style:none;width:11.11111%}.large-block-grid-9>li:nth-of-type(1n){clear:none}.large-block-grid-9>li:nth-of-type(9n+1){clear:both}.large-block-grid-9>li:nth-of-type(9n+1){padding-left:0;padding-right:17.77778px}.large-block-grid-9>li:nth-of-type(9n+2){padding-left:2.22222px;padding-right:15.55556px}.large-block-grid-9>li:nth-of-type(9n+3){padding-left:4.44444px;padding-right:13.33333px}.large-block-grid-9>li:nth-of-type(9n+4){padding-left:6.66667px;padding-right:11.11111px}.large-block-grid-9>li:nth-of-type(9n+5){padding-left:8.88889px;padding-right:8.88889px}.large-block-grid-9>li:nth-of-type(9n+6){padding-left:11.11111px;padding-right:6.66667px}.large-block-grid-9>li:nth-of-type(9n+7){padding-left:13.33333px;padding-right:4.44444px}.large-block-grid-9>li:nth-of-type(9n+8){padding-left:15.55556px;padding-right:2.22222px}.large-block-grid-9>li:nth-of-type(9n){padding-left:17.77778px;padding-right:0}.large-block-grid-10>li{list-style:none;width:10%}.large-block-grid-10>li:nth-of-type(1n){clear:none}.large-block-grid-10>li:nth-of-type(10n+1){clear:both}.large-block-grid-10>li:nth-of-type(10n+1){padding-left:0;padding-right:18px}.large-block-grid-10>li:nth-of-type(10n+2){padding-left:2px;padding-right:16px}.large-block-grid-10>li:nth-of-type(10n+3){padding-left:4px;padding-right:14px}.large-block-grid-10>li:nth-of-type(10n+4){padding-left:6px;padding-right:12px}.large-block-grid-10>li:nth-of-type(10n+5){padding-left:8px;padding-right:10px}.large-block-grid-10>li:nth-of-type(10n+6){padding-left:10px;padding-right:8px}.large-block-grid-10>li:nth-of-type(10n+7){padding-left:12px;padding-right:6px}.large-block-grid-10>li:nth-of-type(10n+8){padding-left:14px;padding-right:4px}.large-block-grid-10>li:nth-of-type(10n+9){padding-left:16px;padding-right:2px}.large-block-grid-10>li:nth-of-type(10n){padding-left:18px;padding-right:0}.large-block-grid-11>li{list-style:none;width:9.09091%}.large-block-grid-11>li:nth-of-type(1n){clear:none}.large-block-grid-11>li:nth-of-type(11n+1){clear:both}.large-block-grid-11>li:nth-of-type(11n+1){padding-left:0;padding-right:18.18182px}.large-block-grid-11>li:nth-of-type(11n+2){padding-left:1.81818px;padding-right:16.36364px}.large-block-grid-11>li:nth-of-type(11n+3){padding-left:3.63636px;padding-right:14.54545px}.large-block-grid-11>li:nth-of-type(11n+4){padding-left:5.45455px;padding-right:12.72727px}.large-block-grid-11>li:nth-of-type(11n+5){padding-left:7.27273px;padding-right:10.90909px}.large-block-grid-11>li:nth-of-type(11n+6){padding-left:9.09091px;padding-right:9.09091px}.large-block-grid-11>li:nth-of-type(11n+7){padding-left:10.90909px;padding-right:7.27273px}.large-block-grid-11>li:nth-of-type(11n+8){padding-left:12.72727px;padding-right:5.45455px}.large-block-grid-11>li:nth-of-type(11n+9){padding-left:14.54545px;padding-right:3.63636px}.large-block-grid-11>li:nth-of-type(11n+10){padding-left:16.36364px;padding-right:1.81818px}.large-block-grid-11>li:nth-of-type(11n){padding-left:18.18182px;padding-right:0}.large-block-grid-12>li{list-style:none;width:8.33333%}.large-block-grid-12>li:nth-of-type(1n){clear:none}.large-block-grid-12>li:nth-of-type(12n+1){clear:both}.large-block-grid-12>li:nth-of-type(12n+1){padding-left:0;padding-right:18.33333px}.large-block-grid-12>li:nth-of-type(12n+2){padding-left:1.66667px;padding-right:16.66667px}.large-block-grid-12>li:nth-of-type(12n+3){padding-left:3.33333px;padding-right:15px}.large-block-grid-12>li:nth-of-type(12n+4){padding-left:5px;padding-right:13.33333px}.large-block-grid-12>li:nth-of-type(12n+5){padding-left:6.66667px;padding-right:11.66667px}.large-block-grid-12>li:nth-of-type(12n+6){padding-left:8.33333px;padding-right:10px}.large-block-grid-12>li:nth-of-type(12n+7){padding-left:10px;padding-right:8.33333px}.large-block-grid-12>li:nth-of-type(12n+8){padding-left:11.66667px;padding-right:6.66667px}.large-block-grid-12>li:nth-of-type(12n+9){padding-left:13.33333px;padding-right:5px}.large-block-grid-12>li:nth-of-type(12n+10){padding-left:15px;padding-right:3.33333px}.large-block-grid-12>li:nth-of-type(12n+11){padding-left:16.66667px;padding-right:1.66667px}.large-block-grid-12>li:nth-of-type(12n){padding-left:18.33333px;padding-right:0}}.icon-bar{display:inline-block;font-size:0;width:100%;background:#333}.icon-bar>*{display:block;float:left;font-size:1rem;margin:0 auto;padding:1.25rem;text-align:center;width:25%}.icon-bar>* i,.icon-bar>* img{display:block;margin:0 auto}.icon-bar>* i+label,.icon-bar>* img+label{margin-top:.0625rem}.icon-bar>* i{font-size:1.875rem;vertical-align:middle}.icon-bar>* img{height:1.875rem;width:1.875rem}.icon-bar.label-right>* i,.icon-bar.label-right>* img{display:inline-block;margin:0 .0625rem 0 0}.icon-bar.label-right>* i+label,.icon-bar.label-right>* img+label{margin-top:0}.icon-bar.label-right>* label{display:inline-block}.icon-bar.vertical.label-right>*{text-align:left}.icon-bar.vertical,.icon-bar.small-vertical{height:100%;width:auto}.icon-bar.vertical .item,.icon-bar.small-vertical .item{float:none;margin:auto;width:auto}@media only screen and (min-width:0){.icon-bar.medium-vertical{height:100%;width:auto}.icon-bar.medium-vertical .item{float:none;margin:auto;width:auto}}@media only screen and (min-width:64.063em){.icon-bar.large-vertical{height:100%;width:auto}.icon-bar.large-vertical .item{float:none;margin:auto;width:auto}}.icon-bar>*{font-size:1rem;padding:1.25rem}.icon-bar>* i+label,.icon-bar>* img+label{margin-top:.0625rem;font-size:1rem}.icon-bar>* i{font-size:1.875rem}.icon-bar>* img{height:1.875rem;width:1.875rem}.icon-bar>* label{color:#fff}.icon-bar>* i{color:#fff}.icon-bar>a:hover{background:#3c63af}.icon-bar>a:hover label{color:#fff}.icon-bar>a:hover i{color:#fff}.icon-bar>a.active{background:#3c63af}.icon-bar>a.active label{color:#fff}.icon-bar>a.active i{color:#fff}.icon-bar .item.disabled{cursor:not-allowed;opacity:.7;pointer-events:none}.icon-bar .item.disabled>*{opacity:.7;cursor:not-allowed}.icon-bar.two-up .item{width:50%}.icon-bar.two-up.vertical .item,.icon-bar.two-up.small-vertical .item{width:auto}@media only screen and (min-width:0){.icon-bar.two-up.medium-vertical .item{width:auto}}@media only screen and (min-width:64.063em){.icon-bar.two-up.large-vertical .item{width:auto}}.icon-bar.three-up .item{width:33.3333%}.icon-bar.three-up.vertical .item,.icon-bar.three-up.small-vertical .item{width:auto}@media only screen and (min-width:0){.icon-bar.three-up.medium-vertical .item{width:auto}}@media only screen and (min-width:64.063em){.icon-bar.three-up.large-vertical .item{width:auto}}.icon-bar.four-up .item{width:25%}.icon-bar.four-up.vertical .item,.icon-bar.four-up.small-vertical .item{width:auto}@media only screen and (min-width:0){.icon-bar.four-up.medium-vertical .item{width:auto}}@media only screen and (min-width:64.063em){.icon-bar.four-up.large-vertical .item{width:auto}}.icon-bar.five-up .item{width:20%}.icon-bar.five-up.vertical .item,.icon-bar.five-up.small-vertical .item{width:auto}@media only screen and (min-width:0){.icon-bar.five-up.medium-vertical .item{width:auto}}@media only screen and (min-width:64.063em){.icon-bar.five-up.large-vertical .item{width:auto}}.icon-bar.six-up .item{width:16.66667%}.icon-bar.six-up.vertical .item,.icon-bar.six-up.small-vertical .item{width:auto}@media only screen and (min-width:0){.icon-bar.six-up.medium-vertical .item{width:auto}}@media only screen and (min-width:64.063em){.icon-bar.six-up.large-vertical .item{width:auto}}.icon-bar.seven-up .item{width:14.28571%}.icon-bar.seven-up.vertical .item,.icon-bar.seven-up.small-vertical .item{width:auto}@media only screen and (min-width:0){.icon-bar.seven-up.medium-vertical .item{width:auto}}@media only screen and (min-width:64.063em){.icon-bar.seven-up.large-vertical .item{width:auto}}.icon-bar.eight-up .item{width:12.5%}.icon-bar.eight-up.vertical .item,.icon-bar.eight-up.small-vertical .item{width:auto}@media only screen and (min-width:0){.icon-bar.eight-up.medium-vertical .item{width:auto}}@media only screen and (min-width:64.063em){.icon-bar.eight-up.large-vertical .item{width:auto}}.icon-bar.two-up .item{width:50%}.icon-bar.two-up.vertical .item,.icon-bar.two-up.small-vertical .item{width:auto}@media only screen and (min-width:0){.icon-bar.two-up.medium-vertical .item{width:auto}}@media only screen and (min-width:64.063em){.icon-bar.two-up.large-vertical .item{width:auto}}.icon-bar.three-up .item{width:33.3333%}.icon-bar.three-up.vertical .item,.icon-bar.three-up.small-vertical .item{width:auto}@media only screen and (min-width:0){.icon-bar.three-up.medium-vertical .item{width:auto}}@media only screen and (min-width:64.063em){.icon-bar.three-up.large-vertical .item{width:auto}}.icon-bar.four-up .item{width:25%}.icon-bar.four-up.vertical .item,.icon-bar.four-up.small-vertical .item{width:auto}@media only screen and (min-width:0){.icon-bar.four-up.medium-vertical .item{width:auto}}@media only screen and (min-width:64.063em){.icon-bar.four-up.large-vertical .item{width:auto}}.icon-bar.five-up .item{width:20%}.icon-bar.five-up.vertical .item,.icon-bar.five-up.small-vertical .item{width:auto}@media only screen and (min-width:0){.icon-bar.five-up.medium-vertical .item{width:auto}}@media only screen and (min-width:64.063em){.icon-bar.five-up.large-vertical .item{width:auto}}.icon-bar.six-up .item{width:16.66667%}.icon-bar.six-up.vertical .item,.icon-bar.six-up.small-vertical .item{width:auto}@media only screen and (min-width:0){.icon-bar.six-up.medium-vertical .item{width:auto}}@media only screen and (min-width:64.063em){.icon-bar.six-up.large-vertical .item{width:auto}}.icon-bar.seven-up .item{width:14.28571%}.icon-bar.seven-up.vertical .item,.icon-bar.seven-up.small-vertical .item{width:auto}@media only screen and (min-width:0){.icon-bar.seven-up.medium-vertical .item{width:auto}}@media only screen and (min-width:64.063em){.icon-bar.seven-up.large-vertical .item{width:auto}}.icon-bar.eight-up .item{width:12.5%}.icon-bar.eight-up.vertical .item,.icon-bar.eight-up.small-vertical .item{width:auto}@media only screen and (min-width:0){.icon-bar.eight-up.medium-vertical .item{width:auto}}@media only screen and (min-width:64.063em){.icon-bar.eight-up.large-vertical .item{width:auto}}.inline-list,footer .nav-aux,.nav .nav-user{list-style:none;margin-top:0;margin-bottom:1.0625rem;margin-left:-1.375rem;margin-right:0;overflow:hidden;padding:0}.inline-list>li,footer .nav-aux>li,.nav .nav-user>li{display:block;float:left;list-style:none;margin-left:1.375rem}.inline-list>li>*,footer .nav-aux>li>*,.nav .nav-user>li>*{display:block}.label{display:inline-block;font-family:"arial";font-weight:normal;line-height:1;margin-bottom:auto;position:relative;text-align:center;text-decoration:none;white-space:nowrap;padding:.25rem .5rem .25rem;font-size:.6875rem;background-color:#3c63af;color:#fff}.label.radius{border-radius:5px}.label.round{border-radius:1000px}.label.alert{background-color:#e53350;color:#fff}.label.warning{background-color:#e53350;color:#fff}.label.success{background-color:#16a127;color:#fff}.label.secondary{background-color:#333;color:#fff}.label.info{background-color:#16a127;color:#fff}.range-slider{border:1px solid #ddd;margin:1.25rem 0;position:relative;-ms-touch-action:none;touch-action:none;display:block;height:1rem;width:100%;background:#fafafa}.range-slider.vertical-range{border:1px solid #ddd;margin:1.25rem 0;position:relative;-ms-touch-action:none;touch-action:none;display:inline-block;height:12.5rem;width:1rem}.range-slider.vertical-range .range-slider-handle{bottom:-10.5rem;margin-left:-0.5rem;margin-top:0;position:absolute}.range-slider.vertical-range .range-slider-active-segment{border-bottom-left-radius:inherit;border-bottom-right-radius:inherit;border-top-left-radius:initial;bottom:0;height:auto;width:.875rem}.range-slider.radius{background:#fafafa;border-radius:5px}.range-slider.radius .range-slider-handle{background:#3c63af;border-radius:5px}.range-slider.radius .range-slider-handle:hover{background:#35579a}.range-slider.round{background:#fafafa;border-radius:1000px}.range-slider.round .range-slider-handle{background:#3c63af;border-radius:1000px}.range-slider.round .range-slider-handle:hover{background:#35579a}.range-slider.disabled,.range-slider[disabled]{background:#fafafa;cursor:not-allowed;opacity:.7}.range-slider.disabled .range-slider-handle,.range-slider[disabled] .range-slider-handle{background:#3c63af;cursor:default;opacity:.7}.range-slider.disabled .range-slider-handle:hover,.range-slider[disabled] .range-slider-handle:hover{background:#35579a}.range-slider-active-segment{background:#323232;border-bottom-left-radius:inherit;border-top-left-radius:inherit;display:inline-block;height:.875rem;position:absolute}.range-slider-handle{border:1px solid none;cursor:pointer;display:inline-block;height:1.375rem;position:absolute;top:-0.3125rem;width:2rem;z-index:1;-ms-touch-action:manipulation;touch-action:manipulation;background:#3c63af}.range-slider-handle:hover{background:#35579a}.reveal-modal-bg{background:#000;background:rgba(0,0,0,0.45);bottom:0;display:none;left:0;position:fixed;right:0;top:0;z-index:1004;left:0}.reveal-modal{border-radius:5px;display:none;position:absolute;top:0;visibility:hidden;width:100%;z-index:1005;left:0;background-color:#fff;padding:0;border:solid 0 #666;box-shadow:0}@media only screen and (max-width:90em){.reveal-modal{min-height:100vh}}.reveal-modal .column,.reveal-modal .columns{min-width:0}.reveal-modal>:first-child{margin-top:0}.reveal-modal>:last-child{margin-bottom:0}@media only screen and (min-width:0){.reveal-modal{left:0;margin:0 auto;max-width:61.25rem;right:0;width:100%}}@media only screen and (min-width:0){.reveal-modal{top:0}}.reveal-modal.radius{box-shadow:none;border-radius:5px}.reveal-modal.round{box-shadow:none;border-radius:1000px}.reveal-modal.collapse{padding:0;box-shadow:none}@media only screen and (min-width:0){.reveal-modal.tiny{left:0;margin:0 auto;max-width:61.25rem;right:0;width:30%}}@media only screen and (min-width:0){.reveal-modal.small{left:0;margin:0 auto;max-width:61.25rem;right:0;width:40%}}@media only screen and (min-width:0){.reveal-modal.medium{left:0;margin:0 auto;max-width:61.25rem;right:0;width:60%}}@media only screen and (min-width:0){.reveal-modal.large{left:0;margin:0 auto;max-width:61.25rem;right:0;width:70%}}@media only screen and (min-width:0){.reveal-modal.xlarge{left:0;margin:0 auto;max-width:61.25rem;right:0;width:95%}}.reveal-modal.full{height:100vh;height:100%;left:0;margin-left:0!important;max-width:none!important;min-height:100vh;top:0}@media only screen and (min-width:0){.reveal-modal.full{left:0;margin:0 auto;max-width:61.25rem;right:0;width:100%}}.reveal-modal.toback{z-index:1003}.reveal-modal .close-reveal-modal{color:#aaa;cursor:pointer;font-size:2.5rem;font-weight:bold;line-height:1;position:absolute;top:.625rem;right:1.375rem;text-decoration:none}.tabs{margin-bottom:0!important;margin-left:0}.tabs:before,.tabs:after{content:" ";display:table}.tabs:after{clear:both}.tabs dd,.tabs .tab-title{float:left;list-style:none;margin-bottom:0!important;position:relative}.tabs dd>a,.tabs .tab-title>a{display:block;background-color:#efefef;color:#222;font-family:"arial";font-size:1rem;padding:0}.tabs dd>a:hover,.tabs .tab-title>a:hover{background-color:#e1e1e1}.tabs dd.active>a,.tabs .tab-title.active>a{background-color:#fff;color:#222}.tabs.radius dd:first-child a,.tabs.radius .tab:first-child a{-webkit-border-bottom-left-radius:5px;-webkit-border-top-left-radius:5px;border-bottom-left-radius:5px;border-top-left-radius:5px}.tabs.radius dd:last-child a,.tabs.radius .tab:last-child a{-webkit-border-bottom-right-radius:5px;-webkit-border-top-right-radius:5px;border-bottom-right-radius:5px;border-top-right-radius:5px}.tabs.vertical dd,.tabs.vertical .tab-title{position:inherit;float:none;display:block;top:auto}.tabs-content{margin-bottom:0!important;width:100%}.tabs-content:before,.tabs-content:after{content:" ";display:table}.tabs-content:after{clear:both}.tabs-content>.content{display:none;float:left;padding:0!important 0;width:100%}.tabs-content>.content.active{display:block;float:none}.tabs-content>.content.contained{padding:0!important}.tabs-content.vertical{display:block}.tabs-content.vertical>.content{padding:0 0!important}@media only screen and (min-width:0){.tabs.vertical{float:left;margin:0;margin-bottom:0!important;max-width:20%;width:20%}.tabs-content.vertical{float:left;margin-left:-1px;max-width:80%;padding-left:1rem;width:80%}}.no-js .tabs-content>.content{display:block;float:none}.has-tip{border-bottom:0;color:#333;cursor:pointer;font-weight:normal}.has-tip:hover,.has-tip:focus{border-bottom:0;color:#3c63af}.has-tip.tip-left,.has-tip.tip-right{float:none!important}.tooltip{background:#efefef;color:#333;display:none;font-size:11px;font-weight:normal;line-height:1.3;max-width:300px;padding:1.25rem;position:absolute;width:100%;z-index:1006;left:50%}.tooltip>.nub{border:solid 5px;border-color:transparent transparent #efefef transparent;display:block;height:0;pointer-events:none;position:absolute;top:-10px;width:0;left:5px}.tooltip>.nub.rtl{left:auto;right:5px}.tooltip.radius{border-radius:5px}.tooltip.round{border-radius:1000px}.tooltip.round>.nub{left:2rem}.tooltip.opened{border-bottom:none!important;color:#3c63af!important}.tap-to-close{color:#777;display:block;font-size:.625rem;font-weight:normal}@media only screen{.tooltip>.nub{border-color:transparent transparent #efefef transparent;top:-10px}.tooltip.tip-top>.nub{border-color:#efefef transparent transparent transparent;bottom:-10px;top:auto}.tooltip.tip-left,.tooltip.tip-right{float:none!important}.tooltip.tip-left>.nub{border-color:transparent transparent transparent #efefef;left:auto;margin-top:-5px;right:-10px;top:50%}.tooltip.tip-right>.nub{border-color:transparent #efefef transparent transparent;left:-10px;margin-top:-5px;right:auto;top:50%}.tooltip.tip-override>.nub{border-color:transparent transparent #efefef transparent}.tooltip.tip-override.tip-left>.nub,.tooltip.tip-override.tip-right>.nub{margin-top:0}}meta.foundation-mq-topbar{font-family:"/only screen and (min-width:0em)/";width:0}.contain-to-grid{width:100%;background:#efefef}.contain-to-grid .top-bar,.contain-to-grid .nav-main{margin-bottom:0}.fixed{position:fixed;top:0;width:100%;z-index:99;left:0}.fixed.expanded:not(.top-bar):not(.nav-main){height:auto;max-height:100%;overflow-y:auto;width:100%}.fixed.expanded:not(.top-bar):not(.nav-main) .title-area,.fixed.expanded:not(.top-bar):not(.nav-main) .logo{position:fixed;width:100%;z-index:99}.fixed.expanded:not(.top-bar):not(.nav-main) .top-bar-section{margin-top:auto;z-index:98}.top-bar,.nav-main{background:#efefef;height:auto;line-height:auto;margin-bottom:0;overflow:hidden;position:relative}.top-bar ul,.nav-main ul{list-style:none;margin-bottom:0}.top-bar .row,.nav-main .row{max-width:none}.top-bar form,.nav-main form,.top-bar input,.nav-main input,.top-bar select,.nav-main select{margin-bottom:0}.top-bar input,.nav-main input,.top-bar select,.nav-main select{font-size:.75rem;height:1.75rem;padding-bottom:.35rem;padding-top:.35rem}.top-bar .button,.nav-main .button,.top-bar button,.nav-main button{font-size:.75rem;margin-bottom:0;padding-bottom:.4125rem;padding-top:.4125rem}@media only screen and (max-width:90em){.top-bar .button,.nav-main .button,.top-bar button,.nav-main button{position:relative;top:-1px}}.top-bar .title-area,.nav-main .title-area,.top-bar .logo,.nav-main .logo{margin:0;position:relative}.top-bar .name,.nav-main .name{font-size:16px;height:auto;margin:0}.top-bar .name h1,.nav-main .name h1,.top-bar .name h2,.nav-main .name h2,.top-bar .name h3,.nav-main .name h3,.top-bar .name h4,.nav-main .name h4,.top-bar .name p,.nav-main .name p,.top-bar .name span,.nav-main .name span{font-size:13px;line-height:auto;margin:0}.top-bar .name h1 a,.nav-main .name h1 a,.top-bar .name h2 a,.nav-main .name h2 a,.top-bar .name h3 a,.nav-main .name h3 a,.top-bar .name h4 a,.nav-main .name h4 a,.top-bar .name p a,.nav-main .name p a,.top-bar .name span a,.nav-main .name span a{color:#3c63af;display:block;font-weight:normal;padding:0;width:75%}.top-bar .toggle-topbar,.nav-main .toggle-topbar{position:absolute;right:0;top:0}.top-bar .toggle-topbar a,.nav-main .toggle-topbar a{color:#3c63af;display:block;font-size:false;font-weight:false;height:auto;line-height:auto;padding:0;position:relative;text-transform:false}.top-bar .toggle-topbar.menu-icon,.nav-main .toggle-topbar.menu-icon{margin-top:-16px;top:50%}.top-bar .toggle-topbar.menu-icon a,.nav-main .toggle-topbar.menu-icon a{color:false;height:34px;line-height:33px;padding:0 1.5625rem 0 0;position:relative}.top-bar .toggle-topbar.menu-icon a span::after,.nav-main .toggle-topbar.menu-icon a span::after{content:"";display:block;height:0;position:absolute;margin-top:-8px;top:50%;right:0;box-shadow:0 0 0 1px false,0 7px 0 1px false,0 14px 0 1px false;-webkit-box-shadow:0 0 0 1px false,0 7px 0 1px false,0 14px 0 1px false;width:16px}.top-bar .toggle-topbar.menu-icon a span:hover:after,.nav-main .toggle-topbar.menu-icon a span:hover:after{box-shadow:0 0 0 1px "",0 7px 0 1px "",0 14px 0 1px "";-webkit-box-shadow:0 0 0 1px "",0 7px 0 1px "",0 14px 0 1px ""}.top-bar.expanded,.expanded.nav-main{background:transparent;height:auto}.top-bar.expanded .title-area,.expanded.nav-main .title-area,.top-bar.expanded .logo,.expanded.nav-main .logo{background:#efefef}.top-bar.expanded .toggle-topbar a,.expanded.nav-main .toggle-topbar a{color:false}.top-bar.expanded .toggle-topbar a span::after,.expanded.nav-main .toggle-topbar a span::after{box-shadow:0 0 0 1px false,0 7px 0 1px false,0 14px 0 1px false}@media screen and (-webkit-min-device-pixel-ratio:0){.top-bar.expanded .top-bar-section .has-dropdown.moved>.dropdown,.expanded.nav-main .top-bar-section .has-dropdown.moved>.dropdown,.top-bar.expanded .top-bar-section .dropdown,.expanded.nav-main .top-bar-section .dropdown{clip:initial}.top-bar.expanded .top-bar-section .has-dropdown:not(.moved)>ul,.expanded.nav-main .top-bar-section .has-dropdown:not(.moved)>ul{padding:0}}.top-bar-section{left:0;position:relative;width:auto;transition:left 300ms ease-out}.top-bar-section ul{display:block;font-size:16px;height:auto;margin:0;padding:0;width:100%}.top-bar-section .divider,.top-bar-section [role="separator"]{border-top:solid 1px #787878;clear:both;height:1px;width:100%}.top-bar-section ul li{background:#efefef}.top-bar-section ul li>a{color:#3c63af;display:block;font-family:"arial";font-size:13px;font-weight:normal;padding-left:0;padding:12px 0 12px 0;text-transform:none;width:100%}.top-bar-section ul li>a.button{font-size:13px;padding-left:0;padding-right:0;background-color:#3c63af;border-color:#304f8c;color:#fff}.top-bar-section ul li>a.button:hover,.top-bar-section ul li>a.button:focus{background-color:#304f8c}.top-bar-section ul li>a.button:hover,.top-bar-section ul li>a.button:focus{color:#fff}.top-bar-section ul li>a.button.secondary{background-color:#333;border-color:#292929;color:#fff}.top-bar-section ul li>a.button.secondary:hover,.top-bar-section ul li>a.button.secondary:focus{background-color:#292929}.top-bar-section ul li>a.button.secondary:hover,.top-bar-section ul li>a.button.secondary:focus{color:#fff}.top-bar-section ul li>a.button.success{background-color:#16a127;border-color:#12811f;color:#fff}.top-bar-section ul li>a.button.success:hover,.top-bar-section ul li>a.button.success:focus{background-color:#12811f}.top-bar-section ul li>a.button.success:hover,.top-bar-section ul li>a.button.success:focus{color:#fff}.top-bar-section ul li>a.button.alert{background-color:#e53350;border-color:#c71936;color:#fff}.top-bar-section ul li>a.button.alert:hover,.top-bar-section ul li>a.button.alert:focus{background-color:#c71936}.top-bar-section ul li>a.button.alert:hover,.top-bar-section ul li>a.button.alert:focus{color:#fff}.top-bar-section ul li>a.button.warning{background-color:#e53350;border-color:#c71936;color:#fff}.top-bar-section ul li>a.button.warning:hover,.top-bar-section ul li>a.button.warning:focus{background-color:#c71936}.top-bar-section ul li>a.button.warning:hover,.top-bar-section ul li>a.button.warning:focus{color:#fff}.top-bar-section ul li>a.button.info{background-color:#16a127;border-color:#12811f;color:#fff}.top-bar-section ul li>a.button.info:hover,.top-bar-section ul li>a.button.info:focus{background-color:#12811f}.top-bar-section ul li>a.button.info:hover,.top-bar-section ul li>a.button.info:focus{color:#fff}.top-bar-section ul li>button{font-size:13px;padding-left:0;padding-right:0;background-color:#3c63af;border-color:#304f8c;color:#fff}.top-bar-section ul li>button:hover,.top-bar-section ul li>button:focus{background-color:#304f8c}.top-bar-section ul li>button:hover,.top-bar-section ul li>button:focus{color:#fff}.top-bar-section ul li>button.secondary{background-color:#333;border-color:#292929;color:#fff}.top-bar-section ul li>button.secondary:hover,.top-bar-section ul li>button.secondary:focus{background-color:#292929}.top-bar-section ul li>button.secondary:hover,.top-bar-section ul li>button.secondary:focus{color:#fff}.top-bar-section ul li>button.success{background-color:#16a127;border-color:#12811f;color:#fff}.top-bar-section ul li>button.success:hover,.top-bar-section ul li>button.success:focus{background-color:#12811f}.top-bar-section ul li>button.success:hover,.top-bar-section ul li>button.success:focus{color:#fff}.top-bar-section ul li>button.alert{background-color:#e53350;border-color:#c71936;color:#fff}.top-bar-section ul li>button.alert:hover,.top-bar-section ul li>button.alert:focus{background-color:#c71936}.top-bar-section ul li>button.alert:hover,.top-bar-section ul li>button.alert:focus{color:#fff}.top-bar-section ul li>button.warning{background-color:#e53350;border-color:#c71936;color:#fff}.top-bar-section ul li>button.warning:hover,.top-bar-section ul li>button.warning:focus{background-color:#c71936}.top-bar-section ul li>button.warning:hover,.top-bar-section ul li>button.warning:focus{color:#fff}.top-bar-section ul li>button.info{background-color:#16a127;border-color:#12811f;color:#fff}.top-bar-section ul li>button.info:hover,.top-bar-section ul li>button.info:focus{background-color:#12811f}.top-bar-section ul li>button.info:hover,.top-bar-section ul li>button.info:focus{color:#fff}.top-bar-section ul li:hover:not(.has-form)>a{background-color:#555;color:#fff;background:#3c63af}.top-bar-section ul li.active>a{background:#ffd87a;color:#ffd87a}.top-bar-section ul li.active>a:hover{background:#3c63af;color:#fff}.top-bar-section .has-form{padding:0}.top-bar-section .has-dropdown{position:relative}.top-bar-section .has-dropdown>a:after{margin-right:0;margin-top:-false/2-2;position:absolute;top:50%;right:0}.top-bar-section .has-dropdown.moved{position:static}.top-bar-section .has-dropdown.moved>.dropdown{position:static!important;height:auto;width:auto;overflow:visible;clip:auto;display:block;position:absolute!important;width:100%}.top-bar-section .has-dropdown.moved>a:after{display:none}.top-bar-section .dropdown{clip:rect(1px,1px,1px,1px);height:1px;overflow:hidden;position:absolute!important;width:1px;display:block;padding:0;position:absolute;top:0;z-index:99;left:100%}.top-bar-section .dropdown li{height:auto;width:100%}.top-bar-section .dropdown li a{font-weight:normal;padding:8px 0}.top-bar-section .dropdown li a.parent-link{font-weight:normal}.top-bar-section .dropdown li.title h5,.top-bar-section .dropdown li.parent-link{margin-bottom:0;margin-top:0;font-size:1.125rem}.top-bar-section .dropdown li.title h5 a,.top-bar-section .dropdown li.parent-link a{color:#3c63af;display:block}.top-bar-section .dropdown li.title h5 a:hover,.top-bar-section .dropdown li.parent-link a:hover{background:0}.top-bar-section .dropdown li.has-form{padding:8px 0}.top-bar-section .dropdown li .button,.top-bar-section .dropdown li button{top:auto}.top-bar-section .dropdown label{color:false;font-size:false;font-weight:false;margin-bottom:0;padding:8px 0 2px;text-transform:false}.js-generated{display:block}@media only screen and (min-width:0){.top-bar,.nav-main{background:#efefef;overflow:visible}.top-bar:before,.nav-main:before,.top-bar:after,.nav-main:after{content:" ";display:table}.top-bar:after,.nav-main:after{clear:both}.top-bar .toggle-topbar,.nav-main .toggle-topbar{display:none}.top-bar .title-area,.nav-main .title-area,.top-bar .logo,.nav-main .logo{float:left}.top-bar .name h1 a,.nav-main .name h1 a,.top-bar .name h2 a,.nav-main .name h2 a,.top-bar .name h3 a,.nav-main .name h3 a,.top-bar .name h4 a,.nav-main .name h4 a,.top-bar .name h5 a,.nav-main .name h5 a,.top-bar .name h6 a,.nav-main .name h6 a{width:auto}.top-bar input,.nav-main input,.top-bar select,.nav-main select,.top-bar .button,.nav-main .button,.top-bar button,.nav-main button{font-size:.875rem;height:1.75rem;position:relative;top:auto-1.75rem/2}.top-bar .has-form>.button,.nav-main .has-form>.button,.top-bar .has-form>button,.nav-main .has-form>button{font-size:.875rem;height:1.75rem;position:relative;top:auto-1.75rem/2}.top-bar.expanded,.expanded.nav-main{background:#efefef}.contain-to-grid .top-bar,.contain-to-grid .nav-main{margin:0 auto;margin-bottom:0;max-width:61.25rem}.top-bar-section{transition:none 0 0;left:0!important}.top-bar-section ul{display:inline;height:auto!important;width:auto}.top-bar-section ul li{float:left}.top-bar-section ul li .js-generated{display:none}.top-bar-section li:not(.head-search).hover>a:not(.button){background-color:#555;background:#3c63af;color:#fff}.top-bar-section li:not(.head-search):not(.has-form) a:not(.button){background:#efefef;line-height:auto;padding:0}.top-bar-section li:not(.head-search):not(.has-form) a:not(.button):hover{background-color:#555;background:#3c63af}.top-bar-section li:not(.head-search).active:not(.has-form) a:not(.button){background:#ffd87a;color:#ffd87a;line-height:auto;padding:0}.top-bar-section li:not(.head-search).active:not(.has-form) a:not(.button):hover{background:#3c63af;color:#fff}.top-bar-section .has-dropdown.moved{position:relative}.top-bar-section .has-dropdown.moved>.dropdown{clip:rect(1px,1px,1px,1px);height:1px;overflow:hidden;position:absolute!important;width:1px;display:block}.top-bar-section .has-dropdown.hover>.dropdown,.top-bar-section .has-dropdown.not-click:hover>.dropdown{position:static!important;height:auto;width:auto;overflow:visible;clip:auto;display:block;position:absolute!important}.top-bar-section .has-dropdown>a:focus+.dropdown{position:static!important;height:auto;width:auto;overflow:visible;clip:auto;display:block;position:absolute!important}.top-bar-section .has-dropdown .dropdown li.has-dropdown>a:after{border:0;content:"\00bb";top:.1875rem;right:5px}.top-bar-section .dropdown{left:0;background:transparent;min-width:100%;top:auto}.top-bar-section .dropdown li a{background:transparent;color:#333;line-height:auto;padding:12px 0;white-space:nowrap}.top-bar-section .dropdown li:not(.has-form):not(.active)>a:not(.button){background:transparent;color:#333}.top-bar-section .dropdown li:not(.has-form):not(.active):hover>a:not(.button){background-color:#555;color:#fff;background:#222}.top-bar-section .dropdown li label{background:false;white-space:nowrap}.top-bar-section .dropdown li .dropdown{left:100%;top:0}.top-bar-section>ul>.divider,.top-bar-section>ul>[role="separator"]{border-right:solid 1px #f1f1f1;border-bottom:0;border-top:0;clear:none;height:auto;width:0}.top-bar-section .has-form{background:#efefef;height:auto;padding:0}.top-bar-section .right li .dropdown,.top-bar-section .nav .nav-user li .dropdown,.nav .top-bar-section .nav-user li .dropdown,.top-bar-section ul.nav-elements li .dropdown,.top-bar-section .head-search li .dropdown{left:auto;right:0}.top-bar-section .right li .dropdown li .dropdown,.top-bar-section .nav .nav-user li .dropdown li .dropdown,.nav .top-bar-section .nav-user li .dropdown li .dropdown,.top-bar-section ul.nav-elements li .dropdown li .dropdown,.top-bar-section .head-search li .dropdown li .dropdown{right:100%}.top-bar-section .left li .dropdown{right:auto;left:0}.top-bar-section .left li .dropdown li .dropdown{left:100%}.no-js .top-bar-section ul li:hover>a{background-color:#555;background:#3c63af;color:#fff}.no-js .top-bar-section ul li:active>a{background:#ffd87a;color:#ffd87a}.no-js .top-bar-section .has-dropdown:hover>.dropdown{position:static!important;height:auto;width:auto;overflow:visible;clip:auto;display:block;position:absolute!important}.no-js .top-bar-section .has-dropdown>a:focus+.dropdown{position:static!important;height:auto;width:auto;overflow:visible;clip:auto;display:block;position:absolute!important}}.text-left{text-align:left!important}.text-right{text-align:right!important}.text-center,.head-top{text-align:center!important}.text-justify{text-align:justify!important}@media only screen and (max-width:90em){.small-only-text-left{text-align:left!important}.small-only-text-right{text-align:right!important}.small-only-text-center{text-align:center!important}.small-only-text-justify{text-align:justify!important}}@media only screen{.small-text-left{text-align:left!important}.small-text-right{text-align:right!important}.small-text-center{text-align:center!important}.small-text-justify{text-align:justify!important}}@media only screen and (min-width:0) and (max-width:90em){.medium-only-text-left{text-align:left!important}.medium-only-text-right{text-align:right!important}.medium-only-text-center{text-align:center!important}.medium-only-text-justify{text-align:justify!important}}@media only screen and (min-width:0){.medium-text-left{text-align:left!important}.medium-text-right{text-align:right!important}.medium-text-center{text-align:center!important}.medium-text-justify{text-align:justify!important}}@media only screen and (min-width:64.063em) and (max-width:90em){.large-only-text-left{text-align:left!important}.large-only-text-right{text-align:right!important}.large-only-text-center{text-align:center!important}.large-only-text-justify{text-align:justify!important}}@media only screen and (min-width:64.063em){.large-text-left{text-align:left!important}.large-text-right{text-align:right!important}.large-text-center{text-align:center!important}.large-text-justify{text-align:justify!important}}@media only screen and (min-width:90.063em) and (max-width:120em){.xlarge-only-text-left{text-align:left!important}.xlarge-only-text-right{text-align:right!important}.xlarge-only-text-center{text-align:center!important}.xlarge-only-text-justify{text-align:justify!important}}@media only screen and (min-width:90.063em){.xlarge-text-left{text-align:left!important}.xlarge-text-right{text-align:right!important}.xlarge-text-center{text-align:center!important}.xlarge-text-justify{text-align:justify!important}}@media only screen and (min-width:120.0625em) and (max-width:6249999.9375em){.xxlarge-only-text-left{text-align:left!important}.xxlarge-only-text-right{text-align:right!important}.xxlarge-only-text-center{text-align:center!important}.xxlarge-only-text-justify{text-align:justify!important}}@media only screen and (min-width:120.0625em){.xxlarge-text-left{text-align:left!important}.xxlarge-text-right{text-align:right!important}.xxlarge-text-center{text-align:center!important}.xxlarge-text-justify{text-align:justify!important}}div,dl,dt,dd,ul,ol,li,h1,h2,h3,h4,h5,h6,pre,form,p,blockquote,.block-quote,.pullquote,th,td{margin:0;padding:0}a{color:#3c63af;line-height:inherit;text-decoration:none}a:hover,a:focus{color:#333}a img{border:0}p{font-family:inherit;font-size:.8125rem;font-weight:normal;line-height:1.125rem;margin-bottom:.8125rem;text-rendering:optimizeLegibility}p.lead{font-size:1.03125rem;line-height:1.6}p aside{font-size:.8125rem;font-style:italic;line-height:1.125rem}h1,h2,h3,h4,h5,h6{color:#333;font-family:"Open Sans",Arial,Helvetica,sans-serif;font-style:normal;font-weight:normal;line-height:1.25;margin-bottom:1.6875rem;margin-top:0;text-rendering:optimizeLegibility}h1 small,h2 small,h3 small,h4 small,h5 small,h6 small{color:#333;font-size:.75rem;line-height:0}h1{font-size:1rem}h2{font-size:.625rem}h3{font-size:.6875rem}h4{font-size:.6875rem}h5{font-size:.8125rem}h6{font-size:.8125rem}.subheader{line-height:1.3;color:#333;font-weight:bold;margin-top:1.6875rem;margin-bottom:.5625rem}hr{border:solid #ddd;border-width:1px 0 0;clear:both;height:0;margin:1.25rem 0 1.1875rem}em,i{font-style:italic;line-height:inherit}strong,b{font-weight:bold;line-height:inherit}small{font-size:.75rem;line-height:inherit}code{background-color:#c2c2c2;border-color:#aeaeae;border-style:solid;border-width:1px;color:#333;font-family:Consolas,"Liberation Mono",Courier,monospace;font-weight:normal;padding:.125rem .3125rem .0625rem}ul,ol,dl{font-family:inherit;font-size:.8125rem;line-height:1.125rem;list-style-position:outside;margin-bottom:.8125rem}ul{margin-left:1.25rem}ul li ul,ul li ol{margin-left:1.25rem;margin-bottom:0}ul.square li ul,ul.circle li ul,ul.disc li ul{list-style:inherit}ul.square{list-style-type:square;margin-left:1.25rem}ul.circle{list-style-type:circle;margin-left:1.25rem}ul.disc{list-style-type:disc;margin-left:1.25rem}ol{margin-left:1.25rem}ol li ul,ol li ol{margin-left:1.25rem;margin-bottom:0}.no-bullet{list-style-type:none;margin-left:0}.no-bullet li ul,.no-bullet li ol{margin-left:1.25rem;margin-bottom:0;list-style:none}dl dt{margin-bottom:0;font-weight:bold}dl dd{margin-bottom:.8125rem}abbr,acronym{text-transform:uppercase;font-size:90%;color:#333;cursor:help}abbr{text-transform:none}abbr[title]{border-bottom:1px dotted #ddd}blockquote,.block-quote,.pullquote{margin:0 0 .8125rem;padding:0 1.25rem;border-left:.3125rem solid #ccc}blockquote cite,.block-quote cite,.pullquote cite{display:block;font-size:13px;color:#333}blockquote cite:before,.block-quote cite:before,.pullquote cite:before{content:"\2014 \0020"}blockquote cite a,.block-quote cite a,.pullquote cite a,blockquote cite a:visited,.block-quote cite a:visited,.pullquote cite a:visited{color:#3c63af}blockquote,.block-quote,.pullquote,blockquote p,.block-quote p,.pullquote p{line-height:1.125rem;color:#333}.vcard{display:inline-block;margin:0 0 1.25rem 0;border:1px solid #ddd;padding:.625rem .75rem}.vcard li{margin:0;display:block}.vcard .fn{font-weight:bold;font-size:.9375rem}.vevent .summary{font-weight:bold}.vevent abbr{cursor:default;text-decoration:none;font-weight:bold;border:0;padding:0 .0625rem}@media only screen and (min-width:0){h1,h2,h3,h4,h5,h6{line-height:1.25}h1{font-size:1.625rem}h2{font-size:1.25rem}h3{font-size:1rem}h4{font-size:1rem}h5{font-size:.8125rem}h6{font-size:.8125rem}}/*!
 * Copyright (c) 2017 Public Library of Science
 *
 * Permission is hereby granted, free of charge, to any person obtaining a
 * copy of this software and associated documentation files (the "Software"),
 * to deal in the Software without restriction, including without limitation
 * the rights to use, copy, modify, merge, publish, distribute, sublicense,
 * and/or sell copies of the Software, and to permit persons to whom the
 * Software is furnished to do so, subject to the following conditions:
 *
 * The above copyright notice and this permission notice shall be included in
 * all copies or substantial portions of the Software.
 *
 * THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
 * IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
 * FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
 * THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
 * LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
 * FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
 * DEALINGS IN THE SOFTWARE.
 */.plos-row,footer .row,.nav,.nav-main,.top-bar-section .calloutcontainer{margin:0 auto;max-width:61.25rem;width:100%}.plos-row:before,footer .row:before,.nav:before,.nav-main:before,.top-bar-section .calloutcontainer:before,.plos-row:after,footer .row:after,.nav:after,.nav-main:after,.top-bar-section .calloutcontainer:after{content:" ";display:table}.plos-row:after,footer .row:after,.nav:after,.nav-main:after,.top-bar-section .calloutcontainer:after{clear:both}.plos-column-0{width:0rem;float:left;margin-left:.625rem;margin-right:.625rem}.plos-column-1{width:5.10417rem;float:left;margin-left:.625rem;margin-right:.625rem}.plos-column-2{width:10.20833rem;float:left;margin-left:.625rem;margin-right:.625rem}.plos-column-3,footer .link-column{width:15.3125rem;float:left;margin-left:.625rem;margin-right:.625rem}.plos-column-4{width:20.41667rem;float:left;margin-left:.625rem;margin-right:.625rem}.plos-column-5,footer .brand-column{width:25.52083rem;float:left;margin-left:.625rem;margin-right:.625rem}.plos-column-6{width:30.625rem;float:left;margin-left:.625rem;margin-right:.625rem}.plos-column-7{width:35.72917rem;float:left;margin-left:.625rem;margin-right:.625rem}.plos-column-8{width:40.83333rem;float:left;margin-left:.625rem;margin-right:.625rem}.plos-column-9{width:45.9375rem;float:left;margin-left:.625rem;margin-right:.625rem}.plos-column-10{width:51.04167rem;float:left;margin-left:.625rem;margin-right:.625rem}.plos-column-11{width:56.14583rem;float:left;margin-left:.625rem;margin-right:.625rem}.plos-column-third{width:20.41667rem;float:left;margin-left:.625rem;margin-right:.625rem}.plos-column-half{width:30.625rem;float:left;margin-left:.625rem;margin-right:.625rem}main,#pagehdr{display:block;margin:0 auto;max-width:61.25rem;width:100%;min-width:61.25rem;max-width:61.25rem;margin:0 auto}main:before,main:after,#pagehdr:before,#pagehdr:after{content:" ";display:table}main:after,#pagehdr:after{clear:both}main.width-full,#pagehdr.width-full{width:100%;max-width:100%}/*!
 *  Font Awesome 4.1.0 by @davegandy - http://fontawesome.io - @fontawesome
 *  License - http://fontawesome.io/license (Font: SIL OFL 1.1, CSS: MIT License)
 */@font-face{font-family:'FontAwesome';src:url("../fonts/fontawesome-webfont.eot?v=4.1.0");src:url("../fonts/fontawesome-webfont.eot?#iefix&v=4.1.0") format("embedded-opentype"),url("../fonts/fontawesome-webfont.woff?v=4.1.0") format("woff"),url("../fonts/fontawesome-webfont.ttf?v=4.1.0") format("truetype"),url("../fonts/fontawesome-webfont.svg?v=4.1.0#fontawesomeregular") format("svg");font-weight:normal;font-style:normal}.fa,.list-bullet>li:before,.bulleted>li:before,.more-icon,.icon-fa,.icon-spinner,.icon-twitter,.icon-facebook,.icon-rss,.icon-email,.icon-minus,.icon-plus-no-square,.icon-plus,.icon-close,.icon-alert,.icon-important,.block-important:after,.icon-arrow-right,.icon-arrow-left,.icon-caret-down,.icon-caret-left,.previous-page .icon:before,.icon-caret-right,.level-active li a:not(.no-children)::after,.level-selection .level-scroll a:not(.no-children)::after,.next-page .icon:before,.icon-angle-up,.levels .up,.icon-angle-down,.levels .down,.icon-angle-right,.icon-angle-left,.icon-chevron-left,.levels .prev,.icon-chevron-right,.levels .next,.icon-circle,.icon-times-circle,.icon-pointer,.block-tip:after,.icon-info,.block-more-information:after,.icon-warning,.icon-bell,.top-bar-section .head-search form button[type="submit"] .search-icon,.editors-search-filter .editors-search-reset,.results .editors-list .section-editor-icon{display:inline-block;font-family:FontAwesome;font-style:normal;font-weight:normal;line-height:1;-webkit-font-smoothing:antialiased;-moz-osx-font-smoothing:grayscale}.fa-lg{font-size:1.33333333em;line-height:.75em;vertical-align:-15%}.fa-2x{font-size:2em}.fa-3x{font-size:3em}.fa-4x{font-size:4em}.fa-5x{font-size:5em}.fa-fw{width:1.28571429em;text-align:center}.fa-ul{padding-left:0;margin-left:2.14285714em;list-style-type:none}.fa-ul>li{position:relative}.fa-li{position:absolute;left:-2.14285714em;width:2.14285714em;top:.14285714em;text-align:center}.fa-li.fa-lg{left:-1.85714286em}.fa-border{padding:.2em .25em .15em;border:solid .08em #eee;border-radius:.1em}.pull-right{float:right}.pull-left{float:left}.fa.pull-left,.list-bullet>li.pull-left:before,.bulleted>li.pull-left:before,.pull-left.more-icon,.pull-left.icon-fa,.pull-left.icon-spinner,.pull-left.icon-twitter,.pull-left.icon-facebook,.pull-left.icon-rss,.pull-left.icon-email,.pull-left.icon-minus,.pull-left.icon-plus-no-square,.pull-left.icon-plus,.pull-left.icon-close,.pull-left.icon-alert,.pull-left.icon-important,.pull-left.block-important:after,.pull-left.icon-arrow-right,.pull-left.icon-arrow-left,.pull-left.icon-caret-down,.pull-left.icon-caret-left,.previous-page .pull-left.icon:before,.pull-left.icon-caret-right,.level-active li a.pull-left:not(.no-children)::after,.level-selection .level-scroll a.pull-left:not(.no-children)::after,.next-page .pull-left.icon:before,.pull-left.icon-angle-up,.levels .pull-left.up,.pull-left.icon-angle-down,.levels .pull-left.down,.pull-left.icon-angle-right,.pull-left.icon-angle-left,.pull-left.icon-chevron-left,.levels .pull-left.prev,.pull-left.icon-chevron-right,.levels .pull-left.next,.pull-left.icon-circle,.pull-left.icon-times-circle,.pull-left.icon-pointer,.pull-left.block-tip:after,.pull-left.icon-info,.pull-left.block-more-information:after,.pull-left.icon-warning,.pull-left.icon-bell,.top-bar-section .head-search form button[type="submit"] .pull-left.search-icon,.editors-search-filter .pull-left.editors-search-reset,.results .editors-list .pull-left.section-editor-icon{margin-right:.3em}.fa.pull-right,.list-bullet>li.pull-right:before,.bulleted>li.pull-right:before,.pull-right.more-icon,.pull-right.icon-fa,.pull-right.icon-spinner,.pull-right.icon-twitter,.pull-right.icon-facebook,.pull-right.icon-rss,.pull-right.icon-email,.pull-right.icon-minus,.pull-right.icon-plus-no-square,.pull-right.icon-plus,.pull-right.icon-close,.pull-right.icon-alert,.pull-right.icon-important,.pull-right.block-important:after,.pull-right.icon-arrow-right,.pull-right.icon-arrow-left,.pull-right.icon-caret-down,.pull-right.icon-caret-left,.previous-page .pull-right.icon:before,.pull-right.icon-caret-right,.level-active li a.pull-right:not(.no-children)::after,.level-selection .level-scroll a.pull-right:not(.no-children)::after,.next-page .pull-right.icon:before,.pull-right.icon-angle-up,.levels .pull-right.up,.pull-right.icon-angle-down,.levels .pull-right.down,.pull-right.icon-angle-right,.pull-right.icon-angle-left,.pull-right.icon-chevron-left,.levels .pull-right.prev,.pull-right.icon-chevron-right,.levels .pull-right.next,.pull-right.icon-circle,.pull-right.icon-times-circle,.pull-right.icon-pointer,.pull-right.block-tip:after,.pull-right.icon-info,.pull-right.block-more-information:after,.pull-right.icon-warning,.pull-right.icon-bell,.top-bar-section .head-search form button[type="submit"] .pull-right.search-icon,.editors-search-filter .pull-right.editors-search-reset,.results .editors-list .pull-right.section-editor-icon{margin-left:.3em}.fa-spin,.icon-spinner{-webkit-animation:spin 2s infinite linear;-moz-animation:spin 2s infinite linear;-o-animation:spin 2s infinite linear;animation:spin 2s infinite linear}@-moz-keyframes spin{0%{-moz-transform:rotate(0deg)}100%{-moz-transform:rotate(359deg)}}@-webkit-keyframes spin{0%{-webkit-transform:rotate(0deg)}100%{-webkit-transform:rotate(359deg)}}@-o-keyframes spin{0%{-o-transform:rotate(0deg)}100%{-o-transform:rotate(359deg)}}@keyframes spin{0%{-webkit-transform:rotate(0deg);transform:rotate(0deg)}100%{-webkit-transform:rotate(359deg);transform:rotate(359deg)}}.fa-rotate-90{filter:progid:DXImageTransform.Microsoft.BasicImage(rotation=1);-webkit-transform:rotate(90deg);-moz-transform:rotate(90deg);-ms-transform:rotate(90deg);-o-transform:rotate(90deg);transform:rotate(90deg)}.fa-rotate-180{filter:progid:DXImageTransform.Microsoft.BasicImage(rotation=2);-webkit-transform:rotate(180deg);-moz-transform:rotate(180deg);-ms-transform:rotate(180deg);-o-transform:rotate(180deg);transform:rotate(180deg)}.fa-rotate-270{filter:progid:DXImageTransform.Microsoft.BasicImage(rotation=3);-webkit-transform:rotate(270deg);-moz-transform:rotate(270deg);-ms-transform:rotate(270deg);-o-transform:rotate(270deg);transform:rotate(270deg)}.fa-flip-horizontal{filter:progid:DXImageTransform.Microsoft.BasicImage(rotation=0,mirror=1);-webkit-transform:scale(-1,1);-moz-transform:scale(-1,1);-ms-transform:scale(-1,1);-o-transform:scale(-1,1);transform:scale(-1,1)}.fa-flip-vertical{filter:progid:DXImageTransform.Microsoft.BasicImage(rotation=2,mirror=1);-webkit-transform:scale(1,-1);-moz-transform:scale(1,-1);-ms-transform:scale(1,-1);-o-transform:scale(1,-1);transform:scale(1,-1)}.fa-stack{position:relative;display:inline-block;width:2em;height:2em;line-height:2em;vertical-align:middle}.fa-stack-1x,.fa-stack-2x{position:absolute;left:0;width:100%;text-align:center}.fa-stack-1x{line-height:inherit}.fa-stack-2x{font-size:2em}.fa-inverse,.more-icon,.levels .next:hover,.levels .prev:hover,.level-active .down:hover,.level-active .up:hover{color:#3c63af}.fa-glass:before{content:"\f000"}.fa-music:before{content:"\f001"}.fa-search:before,.top-bar-section .head-search form button[type="submit"] .search-icon:before{content:"\f002"}.fa-envelope-o:before,.icon-email:before{content:"\f003"}.fa-heart:before{content:"\f004"}.fa-star:before{content:"\f005"}.fa-star-o:before{content:"\f006"}.fa-user:before{content:"\f007"}.fa-film:before{content:"\f008"}.fa-th-large:before{content:"\f009"}.fa-th:before{content:"\f00a"}.fa-th-list:before{content:"\f00b"}.fa-check:before{content:"\f00c"}.fa-times:before,.editors-search-filter .editors-search-reset:before{content:"\f00d"}.fa-search-plus:before{content:"\f00e"}.fa-search-minus:before{content:"\f010"}.fa-power-off:before{content:"\f011"}.fa-signal:before{content:"\f012"}.fa-gear:before,.fa-cog:before{content:"\f013"}.fa-trash-o:before{content:"\f014"}.fa-home:before{content:"\f015"}.fa-file-o:before{content:"\f016"}.fa-clock-o:before{content:"\f017"}.fa-road:before{content:"\f018"}.fa-download:before{content:"\f019"}.fa-arrow-circle-o-down:before{content:"\f01a"}.fa-arrow-circle-o-up:before{content:"\f01b"}.fa-inbox:before{content:"\f01c"}.fa-play-circle-o:before{content:"\f01d"}.fa-rotate-right:before,.fa-repeat:before{content:"\f01e"}.fa-refresh:before{content:"\f021"}.fa-list-alt:before{content:"\f022"}.fa-lock:before{content:"\f023"}.fa-flag:before{content:"\f024"}.fa-headphones:before{content:"\f025"}.fa-volume-off:before{content:"\f026"}.fa-volume-down:before{content:"\f027"}.fa-volume-up:before{content:"\f028"}.fa-qrcode:before{content:"\f029"}.fa-barcode:before{content:"\f02a"}.fa-tag:before{content:"\f02b"}.fa-tags:before{content:"\f02c"}.fa-book:before{content:"\f02d"}.fa-bookmark:before{content:"\f02e"}.fa-print:before{content:"\f02f"}.fa-camera:before{content:"\f030"}.fa-font:before{content:"\f031"}.fa-bold:before{content:"\f032"}.fa-italic:before{content:"\f033"}.fa-text-height:before{content:"\f034"}.fa-text-width:before{content:"\f035"}.fa-align-left:before{content:"\f036"}.fa-align-center:before{content:"\f037"}.fa-align-right:before{content:"\f038"}.fa-align-justify:before{content:"\f039"}.fa-list:before{content:"\f03a"}.fa-dedent:before,.fa-outdent:before{content:"\f03b"}.fa-indent:before{content:"\f03c"}.fa-video-camera:before{content:"\f03d"}.fa-photo:before,.fa-image:before,.fa-picture-o:before{content:"\f03e"}.fa-pencil:before{content:"\f040"}.fa-map-marker:before{content:"\f041"}.fa-adjust:before{content:"\f042"}.fa-tint:before{content:"\f043"}.fa-edit:before,.fa-pencil-square-o:before{content:"\f044"}.fa-share-square-o:before{content:"\f045"}.fa-check-square-o:before{content:"\f046"}.fa-arrows:before{content:"\f047"}.fa-step-backward:before{content:"\f048"}.fa-fast-backward:before{content:"\f049"}.fa-backward:before{content:"\f04a"}.fa-play:before,.results .editors-list .section-editor-icon:before{content:"\f04b"}.fa-pause:before{content:"\f04c"}.fa-stop:before{content:"\f04d"}.fa-forward:before{content:"\f04e"}.fa-fast-forward:before{content:"\f050"}.fa-step-forward:before{content:"\f051"}.fa-eject:before{content:"\f052"}.fa-chevron-left:before,.icon-chevron-left:before,.levels .prev:before{content:"\f053"}.fa-chevron-right:before,.list-bullet>li:before,.bulleted>li:before,.icon-chevron-right:before,.levels .next:before{content:"\f054"}.fa-plus-circle:before{content:"\f055"}.fa-minus-circle:before{content:"\f056"}.fa-times-circle:before,.icon-times-circle:before{content:"\f057"}.fa-check-circle:before{content:"\f058"}.fa-question-circle:before{content:"\f059"}.fa-info-circle:before,.icon-info:before{content:"\f05a"}.fa-crosshairs:before{content:"\f05b"}.fa-times-circle-o:before{content:"\f05c"}.fa-check-circle-o:before{content:"\f05d"}.fa-ban:before{content:"\f05e"}.fa-arrow-left:before,.icon-arrow-left:before{content:"\f060"}.fa-arrow-right:before,.icon-arrow-right:before{content:"\f061"}.fa-arrow-up:before{content:"\f062"}.fa-arrow-down:before{content:"\f063"}.fa-mail-forward:before,.fa-share:before{content:"\f064"}.fa-expand:before{content:"\f065"}.fa-compress:before{content:"\f066"}.fa-plus:before,.icon-plus-no-square:before{content:"\f067"}.fa-minus:before,.icon-minus:before{content:"\f068"}.fa-asterisk:before{content:"\f069"}.fa-exclamation-circle:before,.icon-important:before{content:"\f06a"}.fa-gift:before{content:"\f06b"}.fa-leaf:before{content:"\f06c"}.fa-fire:before{content:"\f06d"}.fa-eye:before{content:"\f06e"}.fa-eye-slash:before{content:"\f070"}.fa-warning:before,.icon-warning:before,.fa-exclamation-triangle:before,.icon-alert:before{content:"\f071"}.fa-plane:before{content:"\f072"}.fa-calendar:before{content:"\f073"}.fa-random:before{content:"\f074"}.fa-comment:before{content:"\f075"}.fa-magnet:before{content:"\f076"}.fa-chevron-up:before{content:"\f077"}.fa-chevron-down:before{content:"\f078"}.fa-retweet:before{content:"\f079"}.fa-shopping-cart:before{content:"\f07a"}.fa-folder:before{content:"\f07b"}.fa-folder-open:before{content:"\f07c"}.fa-arrows-v:before{content:"\f07d"}.fa-arrows-h:before{content:"\f07e"}.fa-bar-chart-o:before{content:"\f080"}.fa-twitter-square:before{content:"\f081"}.fa-facebook-square:before{content:"\f082"}.fa-camera-retro:before{content:"\f083"}.fa-key:before{content:"\f084"}.fa-gears:before,.fa-cogs:before{content:"\f085"}.fa-comments:before{content:"\f086"}.fa-thumbs-o-up:before{content:"\f087"}.fa-thumbs-o-down:before{content:"\f088"}.fa-star-half:before{content:"\f089"}.fa-heart-o:before{content:"\f08a"}.fa-sign-out:before{content:"\f08b"}.fa-linkedin-square:before{content:"\f08c"}.fa-thumb-tack:before{content:"\f08d"}.fa-external-link:before{content:"\f08e"}.fa-sign-in:before{content:"\f090"}.fa-trophy:before{content:"\f091"}.fa-github-square:before{content:"\f092"}.fa-upload:before{content:"\f093"}.fa-lemon-o:before{content:"\f094"}.fa-phone:before{content:"\f095"}.fa-square-o:before{content:"\f096"}.fa-bookmark-o:before{content:"\f097"}.fa-phone-square:before{content:"\f098"}.fa-twitter:before,.icon-twitter:before{content:"\f099"}.fa-facebook:before,.icon-facebook:before{content:"\f09a"}.fa-github:before{content:"\f09b"}.fa-unlock:before{content:"\f09c"}.fa-credit-card:before{content:"\f09d"}.fa-rss:before,.icon-rss:before{content:"\f09e"}.fa-hdd-o:before{content:"\f0a0"}.fa-bullhorn:before{content:"\f0a1"}.fa-bell:before,.icon-bell:before{content:"\f0f3"}.fa-certificate:before{content:"\f0a3"}.fa-hand-o-right:before,.icon-pointer:before{content:"\f0a4"}.fa-hand-o-left:before{content:"\f0a5"}.fa-hand-o-up:before{content:"\f0a6"}.fa-hand-o-down:before{content:"\f0a7"}.fa-arrow-circle-left:before{content:"\f0a8"}.fa-arrow-circle-right:before{content:"\f0a9"}.fa-arrow-circle-up:before{content:"\f0aa"}.fa-arrow-circle-down:before{content:"\f0ab"}.fa-globe:before{content:"\f0ac"}.fa-wrench:before{content:"\f0ad"}.fa-tasks:before{content:"\f0ae"}.fa-filter:before{content:"\f0b0"}.fa-briefcase:before{content:"\f0b1"}.fa-arrows-alt:before{content:"\f0b2"}.fa-group:before,.fa-users:before{content:"\f0c0"}.fa-chain:before,.fa-link:before{content:"\f0c1"}.fa-cloud:before{content:"\f0c2"}.fa-flask:before{content:"\f0c3"}.fa-cut:before,.fa-scissors:before{content:"\f0c4"}.fa-copy:before,.fa-files-o:before{content:"\f0c5"}.fa-paperclip:before{content:"\f0c6"}.fa-save:before,.fa-floppy-o:before{content:"\f0c7"}.fa-square:before{content:"\f0c8"}.fa-navicon:before,.fa-reorder:before,.fa-bars:before{content:"\f0c9"}.fa-list-ul:before{content:"\f0ca"}.fa-list-ol:before{content:"\f0cb"}.fa-strikethrough:before{content:"\f0cc"}.fa-underline:before{content:"\f0cd"}.fa-table:before{content:"\f0ce"}.fa-magic:before{content:"\f0d0"}.fa-truck:before{content:"\f0d1"}.fa-pinterest:before{content:"\f0d2"}.fa-pinterest-square:before{content:"\f0d3"}.fa-google-plus-square:before{content:"\f0d4"}.fa-google-plus:before{content:"\f0d5"}.fa-money:before{content:"\f0d6"}.fa-caret-down:before,.icon-caret-down:before{content:"\f0d7"}.fa-caret-up:before{content:"\f0d8"}.fa-caret-left:before{content:"\f0d9"}.fa-caret-right:before{content:"\f0da"}.fa-columns:before{content:"\f0db"}.fa-unsorted:before,.fa-sort:before{content:"\f0dc"}.fa-sort-down:before,.fa-sort-desc:before{content:"\f0dd"}.fa-sort-up:before,.fa-sort-asc:before{content:"\f0de"}.fa-envelope:before{content:"\f0e0"}.fa-linkedin:before{content:"\f0e1"}.fa-rotate-left:before,.fa-undo:before{content:"\f0e2"}.fa-legal:before,.fa-gavel:before{content:"\f0e3"}.fa-dashboard:before,.fa-tachometer:before{content:"\f0e4"}.fa-comment-o:before{content:"\f0e5"}.fa-comments-o:before{content:"\f0e6"}.fa-flash:before,.fa-bolt:before{content:"\f0e7"}.fa-sitemap:before{content:"\f0e8"}.fa-umbrella:before{content:"\f0e9"}.fa-paste:before,.fa-clipboard:before{content:"\f0ea"}.fa-lightbulb-o:before{content:"\f0eb"}.fa-exchange:before{content:"\f0ec"}.fa-cloud-download:before{content:"\f0ed"}.fa-cloud-upload:before{content:"\f0ee"}.fa-user-md:before{content:"\f0f0"}.fa-stethoscope:before{content:"\f0f1"}.fa-suitcase:before{content:"\f0f2"}.fa-bell-o:before{content:"\f0a2"}.fa-coffee:before{content:"\f0f4"}.fa-cutlery:before{content:"\f0f5"}.fa-file-text-o:before{content:"\f0f6"}.fa-building-o:before{content:"\f0f7"}.fa-hospital-o:before{content:"\f0f8"}.fa-ambulance:before{content:"\f0f9"}.fa-medkit:before{content:"\f0fa"}.fa-fighter-jet:before{content:"\f0fb"}.fa-beer:before{content:"\f0fc"}.fa-h-square:before{content:"\f0fd"}.fa-plus-square:before,.icon-plus:before{content:"\f0fe"}.fa-angle-double-left:before{content:"\f100"}.fa-angle-double-right:before{content:"\f101"}.fa-angle-double-up:before{content:"\f102"}.fa-angle-double-down:before{content:"\f103"}.fa-angle-left:before,.icon-angle-left:before{content:"\f104"}.fa-angle-right:before,.icon-angle-right:before{content:"\f105"}.fa-angle-up:before,.icon-angle-up:before,.levels .up:before{content:"\f106"}.fa-angle-down:before,.icon-angle-down:before,.levels .down:before{content:"\f107"}.fa-desktop:before{content:"\f108"}.fa-laptop:before{content:"\f109"}.fa-tablet:before{content:"\f10a"}.fa-mobile-phone:before,.fa-mobile:before{content:"\f10b"}.fa-circle-o:before{content:"\f10c"}.fa-quote-left:before{content:"\f10d"}.fa-quote-right:before{content:"\f10e"}.fa-spinner:before,.icon-spinner:before{content:"\f110"}.fa-circle:before{content:"\f111"}.fa-mail-reply:before,.fa-reply:before{content:"\f112"}.fa-github-alt:before{content:"\f113"}.fa-folder-o:before{content:"\f114"}.fa-folder-open-o:before{content:"\f115"}.fa-smile-o:before{content:"\f118"}.fa-frown-o:before{content:"\f119"}.fa-meh-o:before{content:"\f11a"}.fa-gamepad:before{content:"\f11b"}.fa-keyboard-o:before{content:"\f11c"}.fa-flag-o:before{content:"\f11d"}.fa-flag-checkered:before{content:"\f11e"}.fa-terminal:before{content:"\f120"}.fa-code:before{content:"\f121"}.fa-mail-reply-all:before,.fa-reply-all:before{content:"\f122"}.fa-star-half-empty:before,.fa-star-half-full:before,.fa-star-half-o:before{content:"\f123"}.fa-location-arrow:before{content:"\f124"}.fa-crop:before{content:"\f125"}.fa-code-fork:before{content:"\f126"}.fa-unlink:before,.fa-chain-broken:before{content:"\f127"}.fa-question:before{content:"\f128"}.fa-info:before{content:"\f129"}.fa-exclamation:before{content:"\f12a"}.fa-superscript:before{content:"\f12b"}.fa-subscript:before{content:"\f12c"}.fa-eraser:before{content:"\f12d"}.fa-puzzle-piece:before{content:"\f12e"}.fa-microphone:before{content:"\f130"}.fa-microphone-slash:before{content:"\f131"}.fa-shield:before{content:"\f132"}.fa-calendar-o:before{content:"\f133"}.fa-fire-extinguisher:before{content:"\f134"}.fa-rocket:before{content:"\f135"}.fa-maxcdn:before{content:"\f136"}.fa-chevron-circle-left:before{content:"\f137"}.fa-chevron-circle-right:before{content:"\f138"}.fa-chevron-circle-up:before{content:"\f139"}.fa-chevron-circle-down:before{content:"\f13a"}.fa-html5:before{content:"\f13b"}.fa-css3:before{content:"\f13c"}.fa-anchor:before{content:"\f13d"}.fa-unlock-alt:before{content:"\f13e"}.fa-bullseye:before{content:"\f140"}.fa-ellipsis-h:before{content:"\f141"}.fa-ellipsis-v:before{content:"\f142"}.fa-rss-square:before{content:"\f143"}.fa-play-circle:before{content:"\f144"}.fa-ticket:before{content:"\f145"}.fa-minus-square:before{content:"\f146"}.fa-minus-square-o:before{content:"\f147"}.fa-level-up:before{content:"\f148"}.fa-level-down:before{content:"\f149"}.fa-check-square:before{content:"\f14a"}.fa-pencil-square:before{content:"\f14b"}.fa-external-link-square:before{content:"\f14c"}.fa-share-square:before{content:"\f14d"}.fa-compass:before{content:"\f14e"}.fa-toggle-down:before,.fa-caret-square-o-down:before{content:"\f150"}.fa-toggle-up:before,.fa-caret-square-o-up:before{content:"\f151"}.fa-toggle-right:before,.fa-caret-square-o-right:before{content:"\f152"}.fa-euro:before,.fa-eur:before{content:"\f153"}.fa-gbp:before{content:"\f154"}.fa-dollar:before,.fa-usd:before{content:"\f155"}.fa-rupee:before,.fa-inr:before{content:"\f156"}.fa-cny:before,.fa-rmb:before,.fa-yen:before,.fa-jpy:before{content:"\f157"}.fa-ruble:before,.fa-rouble:before,.fa-rub:before{content:"\f158"}.fa-won:before,.fa-krw:before{content:"\f159"}.fa-bitcoin:before,.fa-btc:before{content:"\f15a"}.fa-file:before{content:"\f15b"}.fa-file-text:before{content:"\f15c"}.fa-sort-alpha-asc:before{content:"\f15d"}.fa-sort-alpha-desc:before{content:"\f15e"}.fa-sort-amount-asc:before{content:"\f160"}.fa-sort-amount-desc:before{content:"\f161"}.fa-sort-numeric-asc:before{content:"\f162"}.fa-sort-numeric-desc:before{content:"\f163"}.fa-thumbs-up:before{content:"\f164"}.fa-thumbs-down:before{content:"\f165"}.fa-youtube-square:before{content:"\f166"}.fa-youtube:before{content:"\f167"}.fa-xing:before{content:"\f168"}.fa-xing-square:before{content:"\f169"}.fa-youtube-play:before{content:"\f16a"}.fa-dropbox:before{content:"\f16b"}.fa-stack-overflow:before{content:"\f16c"}.fa-instagram:before{content:"\f16d"}.fa-flickr:before{content:"\f16e"}.fa-adn:before{content:"\f170"}.fa-bitbucket:before{content:"\f171"}.fa-bitbucket-square:before{content:"\f172"}.fa-tumblr:before{content:"\f173"}.fa-tumblr-square:before{content:"\f174"}.fa-long-arrow-down:before{content:"\f175"}.fa-long-arrow-up:before{content:"\f176"}.fa-long-arrow-left:before{content:"\f177"}.fa-long-arrow-right:before{content:"\f178"}.fa-apple:before{content:"\f179"}.fa-windows:before{content:"\f17a"}.fa-android:before{content:"\f17b"}.fa-linux:before{content:"\f17c"}.fa-dribbble:before{content:"\f17d"}.fa-skype:before{content:"\f17e"}.fa-foursquare:before{content:"\f180"}.fa-trello:before{content:"\f181"}.fa-female:before{content:"\f182"}.fa-male:before{content:"\f183"}.fa-gittip:before{content:"\f184"}.fa-sun-o:before{content:"\f185"}.fa-moon-o:before{content:"\f186"}.fa-archive:before{content:"\f187"}.fa-bug:before{content:"\f188"}.fa-vk:before{content:"\f189"}.fa-weibo:before{content:"\f18a"}.fa-renren:before{content:"\f18b"}.fa-pagelines:before{content:"\f18c"}.fa-stack-exchange:before{content:"\f18d"}.fa-arrow-circle-o-right:before{content:"\f18e"}.fa-arrow-circle-o-left:before{content:"\f190"}.fa-toggle-left:before,.fa-caret-square-o-left:before{content:"\f191"}.fa-dot-circle-o:before{content:"\f192"}.fa-wheelchair:before{content:"\f193"}.fa-vimeo-square:before{content:"\f194"}.fa-turkish-lira:before,.fa-try:before{content:"\f195"}.fa-plus-square-o:before{content:"\f196"}.fa-space-shuttle:before{content:"\f197"}.fa-slack:before{content:"\f198"}.fa-envelope-square:before{content:"\f199"}.fa-wordpress:before{content:"\f19a"}.fa-openid:before{content:"\f19b"}.fa-institution:before,.fa-bank:before,.fa-university:before{content:"\f19c"}.fa-mortar-board:before,.fa-graduation-cap:before{content:"\f19d"}.fa-yahoo:before{content:"\f19e"}.fa-google:before{content:"\f1a0"}.fa-reddit:before{content:"\f1a1"}.fa-reddit-square:before{content:"\f1a2"}.fa-stumbleupon-circle:before{content:"\f1a3"}.fa-stumbleupon:before{content:"\f1a4"}.fa-delicious:before{content:"\f1a5"}.fa-digg:before{content:"\f1a6"}.fa-pied-piper-square:before,.fa-pied-piper:before{content:"\f1a7"}.fa-pied-piper-alt:before{content:"\f1a8"}.fa-drupal:before{content:"\f1a9"}.fa-joomla:before{content:"\f1aa"}.fa-language:before{content:"\f1ab"}.fa-fax:before{content:"\f1ac"}.fa-building:before{content:"\f1ad"}.fa-child:before{content:"\f1ae"}.fa-paw:before{content:"\f1b0"}.fa-spoon:before{content:"\f1b1"}.fa-cube:before{content:"\f1b2"}.fa-cubes:before{content:"\f1b3"}.fa-behance:before{content:"\f1b4"}.fa-behance-square:before{content:"\f1b5"}.fa-steam:before{content:"\f1b6"}.fa-steam-square:before{content:"\f1b7"}.fa-recycle:before{content:"\f1b8"}.fa-automobile:before,.fa-car:before{content:"\f1b9"}.fa-cab:before,.fa-taxi:before{content:"\f1ba"}.fa-tree:before{content:"\f1bb"}.fa-spotify:before{content:"\f1bc"}.fa-deviantart:before{content:"\f1bd"}.fa-soundcloud:before{content:"\f1be"}.fa-database:before{content:"\f1c0"}.fa-file-pdf-o:before{content:"\f1c1"}.fa-file-word-o:before{content:"\f1c2"}.fa-file-excel-o:before{content:"\f1c3"}.fa-file-powerpoint-o:before{content:"\f1c4"}.fa-file-photo-o:before,.fa-file-picture-o:before,.fa-file-image-o:before{content:"\f1c5"}.fa-file-zip-o:before,.fa-file-archive-o:before{content:"\f1c6"}.fa-file-sound-o:before,.fa-file-audio-o:before{content:"\f1c7"}.fa-file-movie-o:before,.fa-file-video-o:before{content:"\f1c8"}.fa-file-code-o:before{content:"\f1c9"}.fa-vine:before{content:"\f1ca"}.fa-codepen:before{content:"\f1cb"}.fa-jsfiddle:before{content:"\f1cc"}.fa-life-bouy:before,.fa-life-saver:before,.fa-support:before,.fa-life-ring:before{content:"\f1cd"}.fa-circle-o-notch:before{content:"\f1ce"}.fa-ra:before,.fa-rebel:before{content:"\f1d0"}.fa-ge:before,.fa-empire:before{content:"\f1d1"}.fa-git-square:before{content:"\f1d2"}.fa-git:before{content:"\f1d3"}.fa-hacker-news:before{content:"\f1d4"}.fa-tencent-weibo:before{content:"\f1d5"}.fa-qq:before{content:"\f1d6"}.fa-wechat:before,.fa-weixin:before{content:"\f1d7"}.fa-send:before,.fa-paper-plane:before{content:"\f1d8"}.fa-send-o:before,.fa-paper-plane-o:before{content:"\f1d9"}.fa-history:before{content:"\f1da"}.fa-circle-thin:before{content:"\f1db"}.fa-header:before{content:"\f1dc"}.fa-paragraph:before{content:"\f1dd"}.fa-sliders:before{content:"\f1de"}.fa-share-alt:before{content:"\f1e0"}.fa-share-alt-square:before{content:"\f1e1"}.fa-bomb:before{content:"\f1e2"}/*!
 * Copyright (c) 2017 Public Library of Science
 *
 * Permission is hereby granted, free of charge, to any person obtaining a
 * copy of this software and associated documentation files (the "Software"),
 * to deal in the Software without restriction, including without limitation
 * the rights to use, copy, modify, merge, publish, distribute, sublicense,
 * and/or sell copies of the Software, and to permit persons to whom the
 * Software is furnished to do so, subject to the following conditions:
 *
 * The above copyright notice and this permission notice shall be included in
 * all copies or substantial portions of the Software.
 *
 * THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
 * IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
 * FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
 * THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
 * LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
 * FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
 * DEALINGS IN THE SOFTWARE.
 */p{word-wrap:break-word}sup,sub{vertical-align:0;position:relative}sub{top:.5ex}sup{bottom:1ex}ol{padding-left:1.25rem}ol li{font-size:.8125rem;line-height:1.125rem;margin-bottom:9px}.list-bullet,.bulleted{list-style-type:none}.list-bullet>li,.bulleted>li{padding-left:1.25rem;margin-bottom:.5625rem;position:relative}.list-bullet>li:before,.bulleted>li:before{content:"\f054";font-size:.625rem;display:inline-block;margin-left:-1.0625rem}.list-bullet-over-ride li:before{content:none;font-size:inherit;display:inline-block;margin-left:0;position:relative}.list-no-bullet,.results .editors-list{margin-left:0;list-style-type:none}.list-no-bullet li,.results .editors-list li{font-size:.8125rem;line-height:1.125rem;margin-bottom:9px}h2,h3,h4,h5{font-family:"arial"}h3,h5{font-weight:bold}h4{font-weight:normal}h2,h3,h4,h5{margin-bottom:.5625rem;margin-top:1.6875rem;line-height:normal}h2{margin-bottom:1.125rem;font-size:1.25rem;font-weight:normal}h3{margin-bottom:1rem;margin-top:1.5rem}h4,h5{margin-top:.5625rem}.title-small,.title-small-sans{font-size:13px;font-weight:bold}.title-medium{font-family:"Open Sans",Arial,Helvetica,sans-serif;font-size:18px}.title-small-sans{font-family:"arial"}.title-primary-large{font-family:"Open Sans",Arial,Helvetica,sans-serif;font-size:32px;line-height:1.25}.title-primary{font-family:"Open Sans",Arial,Helvetica,sans-serif;font-size:26px;line-height:1.25}.title-secondary{font-family:"Open Sans",Arial,Helvetica,sans-serif;font-size:22px;line-height:1.25;margin-bottom:27px}.block-global-alert,.block-aperta{margin:1.6875rem 0 1.125rem 0;padding:1.125rem 1.25rem;font-size:.8125rem;line-height:1.125rem}blockquote,.block-quote,.pullquote,.pullquote,.block-quote{font-size:.8125rem;line-height:1.125rem;border-left:.3125rem solid #ccc;margin:1.6875rem 0 1.125rem 0}.pullquote{font-style:italic}.block-basic{margin:1.6875rem 0 1.125rem 0;padding:1.125rem 1.25rem;font-size:.8125rem;line-height:1.125rem;background:#efefef}.block-global-alert,.block-aperta{background:#abc2e8;font-weight:bold}.block-aperta{background:#8ecb87}.block-tip{margin:1.6875rem 0 1.125rem 0;padding:0;font-size:.8125rem;line-height:1.125rem;padding-left:1.875rem;position:relative}.block-tip:after{display:block;position:absolute;left:0;top:-0.125rem;line-height:1!important}.block-important{margin:1.6875rem 0 1.125rem 0;padding:1.125rem 1.25rem;font-size:.8125rem;line-height:1.125rem;padding-left:3rem;position:relative;background:#ffd87a}.block-important:after{display:block;position:absolute;left:1.125rem;top:1.125rem;line-height:1!important}.block-more-information{margin:1.6875rem 0 1.125rem 0;padding:1.125rem 1.25rem;font-size:.8125rem;line-height:1.125rem;padding-left:3rem;position:relative;background:#efefef}.block-more-information:after{display:block;position:absolute;left:1.125rem;top:1.125rem;line-height:1!important}.tooltip-aside li a,.tooltip-aside li a a{color:#333;text-decoration:none}.tooltip-aside li a:hover,.tooltip-aside li a a:hover,.tooltip-aside li a:hover a,.tooltip-aside li a a:hover,.tooltip-aside li a a a:hover,.tooltip-aside li a a:hover a{color:#3c63af;text-decoration:none}.taxonomy-header #subjInfoText a,.taxonomy-header #subjInfoText a a{color:#fff;text-decoration:none}.taxonomy-header #subjInfoText a:hover,.taxonomy-header #subjInfoText a a:hover,.taxonomy-header #subjInfoText a:hover a,.taxonomy-header #subjInfoText a a:hover,.taxonomy-header #subjInfoText a a a:hover,.taxonomy-header #subjInfoText a a:hover a{color:#fff;text-decoration:underline}.link-disabled{pointer-events:none;color:#ccc}.type{font-weight:bold}.type:after{content:':'}.header-allcaps-smallest{text-transform:uppercase}.inline-intro{font-weight:bold}.no-margin{margin-bottom:0}.small-caps{font-variant:small-caps}.monospace{font-family:"Courier New",monospace}.roman{font-family:TimesNewRoman,"Times New Roman",Times,Baskerville,Georgia,serif}.sans-serif{font-family:"Arial Narrow",Arial,Helvetica,sans-serif}.note,.caption,figcaption{color:#ccc}table.table-basic,table.table-borders,table.table-zebra-stripes{background:#fff;border:solid .0625rem #ccc;margin-bottom:1.25rem;table-layout:auto;border-collapse:collapse;width:100%}table.table-basic caption,table.table-borders caption,table.table-zebra-stripes caption{background:transparent;color:#333;font-size:1rem;font-weight:bold}table.table-basic thead,table.table-borders thead,table.table-zebra-stripes thead{background:#fff}table.table-basic thead tr th,table.table-borders thead tr th,table.table-zebra-stripes thead tr th,table.table-basic thead tr td,table.table-borders thead tr td,table.table-zebra-stripes thead tr td{color:#333;font-size:.8125rem;font-weight:bold;padding:.5625rem .625rem}table.table-basic tfoot,table.table-borders tfoot,table.table-zebra-stripes tfoot{background:#fff}table.table-basic tfoot tr th,table.table-borders tfoot tr th,table.table-zebra-stripes tfoot tr th,table.table-basic tfoot tr td,table.table-borders tfoot tr td,table.table-zebra-stripes tfoot tr td{color:#333;font-size:.8125rem;font-weight:bold;padding:.5625rem .625rem}table.table-basic tr th,table.table-borders tr th,table.table-zebra-stripes tr th,table.table-basic tr td,table.table-borders tr td,table.table-zebra-stripes tr td{color:#333;font-size:.8125rem;padding:.5625rem .625rem;text-align:left}table.table-basic tr.even,table.table-borders tr.even,table.table-zebra-stripes tr.even,table.table-basic tr.alt,table.table-borders tr.alt,table.table-zebra-stripes tr.alt,table.table-basic tr:nth-of-type(even),table.table-borders tr:nth-of-type(even),table.table-zebra-stripes tr:nth-of-type(even){background:#fff}table.table-basic thead tr th,table.table-borders thead tr th,table.table-zebra-stripes thead tr th,table.table-basic tfoot tr th,table.table-borders tfoot tr th,table.table-zebra-stripes tfoot tr th,table.table-basic tfoot tr td,table.table-borders tfoot tr td,table.table-zebra-stripes tfoot tr td,table.table-basic tbody tr th,table.table-borders tbody tr th,table.table-zebra-stripes tbody tr th,table.table-basic tbody tr td,table.table-borders tbody tr td,table.table-zebra-stripes tbody tr td,table.table-basic tr td,table.table-borders tr td,table.table-zebra-stripes tr td{display:table-cell;line-height:1.125rem}table.table-basic{border-width:0}table.table-basic thead th{border-bottom:1px solid #333}table.table-basic tbody td{border-bottom:1px solid #ccc}table.table-basic tbody tr:last-child td{border-bottom:0}table.table-borders{border:1px solid #ccc}table.table-borders td,table.table-borders th{border:1px solid #ccc}table.table-borders thead th{border-bottom:1px solid #333}table.table-zebra-stripes{border-width:0}table.table-zebra-stripes td,table.table-zebra-stripes th{border-left:1px solid #fff}table.table-zebra-stripes tr{background:#efefef}table.table-zebra-stripes tr.even,table.table-zebra-stripes tr.alt,table.table-zebra-stripes tr:nth-of-type(even){background:#ccc}table.table-zebra-stripes thead tr th{background:#666;color:#fff}.header-allcaps-smallest{font-size:.8125rem;font-family:"Open Sans",Arial,Helvetica,sans-serif}.header-allcaps-smallest{font-family:"arial"}.header-allcaps-smallest{font-size:.625rem}/*!
 * Copyright (c) 2017 Public Library of Science
 *
 * Permission is hereby granted, free of charge, to any person obtaining a
 * copy of this software and associated documentation files (the "Software"),
 * to deal in the Software without restriction, including without limitation
 * the rights to use, copy, modify, merge, publish, distribute, sublicense,
 * and/or sell copies of the Software, and to permit persons to whom the
 * Software is furnished to do so, subject to the following conditions:
 *
 * The above copyright notice and this permission notice shall be included in
 * all copies or substantial portions of the Software.
 *
 * THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
 * IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
 * FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
 * THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
 * LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
 * FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
 * DEALINGS IN THE SOFTWARE.
 *//*!
 * Copyright (c) 2017 Public Library of Science
 *
 * Permission is hereby granted, free of charge, to any person obtaining a
 * copy of this software and associated documentation files (the "Software"),
 * to deal in the Software without restriction, including without limitation
 * the rights to use, copy, modify, merge, publish, distribute, sublicense,
 * and/or sell copies of the Software, and to permit persons to whom the
 * Software is furnished to do so, subject to the following conditions:
 *
 * The above copyright notice and this permission notice shall be included in
 * all copies or substantial portions of the Software.
 *
 * THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
 * IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
 * FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
 * THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
 * LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
 * FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
 * DEALINGS IN THE SOFTWARE.
 */p [data-visibility="none"],div [data-visibility="none"],span [data-visibility="none"],li [data-visibility="none"],ul [data-visibility="none"],ol [data-visibility="none"]{display:none}[data-js-tooltip=tooltip_trigger]:focus{outline:0}.top-bar-section ul.nav-elements .subject-area,.levels .next:hover,.levels .prev:hover,.level-top{-webkit-border-radius:5px;-moz-border-radius:5px;-ms-border-radius:5px;-o-border-radius:5px;border-radius:5px}.levels .up{-moz-border-radius-topleft:5px;-webkit-border-top-left-radius:5px;border-top-left-radius:5px;-moz-border-radius-topright:5px;-webkit-border-top-right-radius:5px;border-top-right-radius:5px}.levels .down{-moz-border-radius-bottomleft:5px;-webkit-border-bottom-left-radius:5px;border-bottom-left-radius:5px;-moz-border-radius-bottomright:5px;-webkit-border-bottom-right-radius:5px;border-bottom-right-radius:5px}footer,.head-top{background:#333}.plosbiology .more-icon,.plosbiology .top-bar-section .calloutcontainer .button-contain a.button-link,.top-bar-section .calloutcontainer .button-contain .plosbiology a.button-link,.plosbiology .results .editors-list .section-editor-icon,.results .editors-list .plosbiology .section-editor-icon,.ploscompbiol .more-icon,.ploscompbiol .top-bar-section .calloutcontainer .button-contain a.button-link,.top-bar-section .calloutcontainer .button-contain .ploscompbiol a.button-link,.ploscompbiol .results .editors-list .section-editor-icon,.results .editors-list .ploscompbiol .section-editor-icon,.plosgenetics .more-icon,.plosgenetics .top-bar-section .calloutcontainer .button-contain a.button-link,.top-bar-section .calloutcontainer .button-contain .plosgenetics a.button-link,.plosgenetics .results .editors-list .section-editor-icon,.results .editors-list .plosgenetics .section-editor-icon{color:#16a127}.plosbiology .head-top,.ploscompbiol .head-top,.plosgenetics .head-top{border-color:#16a127}.plosbiology .action-label,.plosbiology .twitter-typeahead .tt-suggestion.tt-cursor,.twitter-typeahead .plosbiology .tt-suggestion.tt-cursor,.plosbiology .twitter-typeahead .tt-suggestion:hover,.twitter-typeahead .plosbiology .tt-suggestion:hover,.plosbiology .closer-brand,.plosbiology .nav-pagination .active,.nav-pagination .plosbiology .active,.ploscompbiol .action-label,.ploscompbiol .twitter-typeahead .tt-suggestion.tt-cursor,.twitter-typeahead .ploscompbiol .tt-suggestion.tt-cursor,.ploscompbiol .twitter-typeahead .tt-suggestion:hover,.twitter-typeahead .ploscompbiol .tt-suggestion:hover,.ploscompbiol .closer-brand,.ploscompbiol .nav-pagination .active,.nav-pagination .ploscompbiol .active,.plosgenetics .action-label,.plosgenetics .twitter-typeahead .tt-suggestion.tt-cursor,.twitter-typeahead .plosgenetics .tt-suggestion.tt-cursor,.plosgenetics .twitter-typeahead .tt-suggestion:hover,.twitter-typeahead .plosgenetics .tt-suggestion:hover,.plosgenetics .closer-brand,.plosgenetics .nav-pagination .active,.nav-pagination .plosgenetics .active{background-color:#16a127;color:#fff}.plosbiology .button,.plosbiology .button-default,.plosbiology .nav .nav-user li.highlighted>a,.nav .nav-user .plosbiology li.highlighted>a,.ploscompbiol .button,.ploscompbiol .button-default,.ploscompbiol .nav .nav-user li.highlighted>a,.nav .nav-user .ploscompbiol li.highlighted>a,.plosgenetics .button,.plosgenetics .button-default,.plosgenetics .nav .nav-user li.highlighted>a,.nav .nav-user .plosgenetics li.highlighted>a{background-color:#16a127;color:#fff}.plosbiology .button:hover,.plosbiology .button-default:hover,.plosbiology .nav .nav-user li.highlighted>a:hover,.nav .nav-user .plosbiology li.highlighted>a:hover,.ploscompbiol .button:hover,.ploscompbiol .button-default:hover,.ploscompbiol .nav .nav-user li.highlighted>a:hover,.nav .nav-user .ploscompbiol li.highlighted>a:hover,.plosgenetics .button:hover,.plosgenetics .button-default:hover,.plosgenetics .nav .nav-user li.highlighted>a:hover,.nav .nav-user .plosgenetics li.highlighted>a:hover{background-color:#3c63af;color:#fff}.plosmedicine .more-icon,.plosmedicine .top-bar-section .calloutcontainer .button-contain a.button-link,.top-bar-section .calloutcontainer .button-contain .plosmedicine a.button-link,.plosmedicine .results .editors-list .section-editor-icon,.results .editors-list .plosmedicine .section-editor-icon,.plospathogens .more-icon,.plospathogens .top-bar-section .calloutcontainer .button-contain a.button-link,.top-bar-section .calloutcontainer .button-contain .plospathogens a.button-link,.plospathogens .results .editors-list .section-editor-icon,.results .editors-list .plospathogens .section-editor-icon,.plosntd .more-icon,.plosntd .top-bar-section .calloutcontainer .button-contain a.button-link,.top-bar-section .calloutcontainer .button-contain .plosntd a.button-link,.plosntd .results .editors-list .section-editor-icon,.results .editors-list .plosntd .section-editor-icon{color:#891fb1}.plosmedicine .head-top,.plospathogens .head-top,.plosntd .head-top{border-color:#891fb1}.plosmedicine .action-label,.plosmedicine .twitter-typeahead .tt-suggestion.tt-cursor,.twitter-typeahead .plosmedicine .tt-suggestion.tt-cursor,.plosmedicine .twitter-typeahead .tt-suggestion:hover,.twitter-typeahead .plosmedicine .tt-suggestion:hover,.plosmedicine .closer-brand,.plosmedicine .nav-pagination .active,.nav-pagination .plosmedicine .active,.plospathogens .action-label,.plospathogens .twitter-typeahead .tt-suggestion.tt-cursor,.twitter-typeahead .plospathogens .tt-suggestion.tt-cursor,.plospathogens .twitter-typeahead .tt-suggestion:hover,.twitter-typeahead .plospathogens .tt-suggestion:hover,.plospathogens .closer-brand,.plospathogens .nav-pagination .active,.nav-pagination .plospathogens .active,.plosntd .action-label,.plosntd .twitter-typeahead .tt-suggestion.tt-cursor,.twitter-typeahead .plosntd .tt-suggestion.tt-cursor,.plosntd .twitter-typeahead .tt-suggestion:hover,.twitter-typeahead .plosntd .tt-suggestion:hover,.plosntd .closer-brand,.plosntd .nav-pagination .active,.nav-pagination .plosntd .active{background-color:#891fb1;color:#fff}.plosmedicine .button,.plosmedicine .button-default,.plosmedicine .nav .nav-user li.highlighted>a,.nav .nav-user .plosmedicine li.highlighted>a,.plospathogens .button,.plospathogens .button-default,.plospathogens .nav .nav-user li.highlighted>a,.nav .nav-user .plospathogens li.highlighted>a,.plosntd .button,.plosntd .button-default,.plosntd .nav .nav-user li.highlighted>a,.nav .nav-user .plosntd li.highlighted>a{background-color:#891fb1;color:#fff}.plosmedicine .button:hover,.plosmedicine .button-default:hover,.plosmedicine .nav .nav-user li.highlighted>a:hover,.nav .nav-user .plosmedicine li.highlighted>a:hover,.plospathogens .button:hover,.plospathogens .button-default:hover,.plospathogens .nav .nav-user li.highlighted>a:hover,.nav .nav-user .plospathogens li.highlighted>a:hover,.plosntd .button:hover,.plosntd .button-default:hover,.plosntd .nav .nav-user li.highlighted>a:hover,.nav .nav-user .plosntd li.highlighted>a:hover{background-color:#3c63af;color:#fff}.ploscollections .more-icon,.ploscollections .top-bar-section .calloutcontainer .button-contain a.button-link,.top-bar-section .calloutcontainer .button-contain .ploscollections a.button-link,.ploscollections .results .editors-list .section-editor-icon,.results .editors-list .ploscollections .section-editor-icon,.plosclinicaltrials .more-icon,.plosclinicaltrials .top-bar-section .calloutcontainer .button-contain a.button-link,.top-bar-section .calloutcontainer .button-contain .plosclinicaltrials a.button-link,.plosclinicaltrials .results .editors-list .section-editor-icon,.results .editors-list .plosclinicaltrials .section-editor-icon{color:#3c63af}.ploscollections .head-top,.plosclinicaltrials .head-top{border-color:#3c63af}.ploscollections .action-label,.ploscollections .twitter-typeahead .tt-suggestion.tt-cursor,.twitter-typeahead .ploscollections .tt-suggestion.tt-cursor,.ploscollections .twitter-typeahead .tt-suggestion:hover,.twitter-typeahead .ploscollections .tt-suggestion:hover,.ploscollections .closer-brand,.ploscollections .nav-pagination .active,.nav-pagination .ploscollections .active,.plosclinicaltrials .action-label,.plosclinicaltrials .twitter-typeahead .tt-suggestion.tt-cursor,.twitter-typeahead .plosclinicaltrials .tt-suggestion.tt-cursor,.plosclinicaltrials .twitter-typeahead .tt-suggestion:hover,.twitter-typeahead .plosclinicaltrials .tt-suggestion:hover,.plosclinicaltrials .closer-brand,.plosclinicaltrials .nav-pagination .active,.nav-pagination .plosclinicaltrials .active{background-color:#3c63af;color:#fff}.ploscollections .button,.ploscollections .button-default,.ploscollections .nav .nav-user li.highlighted>a,.nav .nav-user .ploscollections li.highlighted>a,.plosclinicaltrials .button,.plosclinicaltrials .button-default,.plosclinicaltrials .nav .nav-user li.highlighted>a,.nav .nav-user .plosclinicaltrials li.highlighted>a{background-color:#3c63af;color:#fff}.ploscollections .button:hover,.ploscollections .button-default:hover,.ploscollections .nav .nav-user li.highlighted>a:hover,.nav .nav-user .ploscollections li.highlighted>a:hover,.plosclinicaltrials .button:hover,.plosclinicaltrials .button-default:hover,.plosclinicaltrials .nav .nav-user li.highlighted>a:hover,.nav .nav-user .plosclinicaltrials li.highlighted>a:hover{background-color:#3c63af;color:#fff}.generic .more-icon,.generic .top-bar-section .calloutcontainer .button-contain a.button-link,.top-bar-section .calloutcontainer .button-contain .generic a.button-link,.generic .results .editors-list .section-editor-icon,.results .editors-list .generic .section-editor-icon{color:#4a1010}.generic .head-top{border-color:#4a1010}.generic .action-label,.generic .twitter-typeahead .tt-suggestion.tt-cursor,.twitter-typeahead .generic .tt-suggestion.tt-cursor,.generic .twitter-typeahead .tt-suggestion:hover,.twitter-typeahead .generic .tt-suggestion:hover,.generic .closer-brand,.generic .nav-pagination .active,.nav-pagination .generic .active{background-color:#4a1010;color:#fff}.generic .button,.generic .button-default,.generic .nav .nav-user li.highlighted>a,.nav .nav-user .generic li.highlighted>a{background-color:#4a1010;color:#fff}.generic .button:hover,.generic .button-default:hover,.generic .nav .nav-user li.highlighted>a:hover,.nav .nav-user .generic li.highlighted>a:hover{background-color:#3c63af;color:#fff}.plosone .more-icon,.plosone .top-bar-section .calloutcontainer .button-contain a.button-link,.top-bar-section .calloutcontainer .button-contain .plosone a.button-link,.plosone .results .editors-list .section-editor-icon,.results .editors-list .plosone .section-editor-icon{color:#f8af2d}.plosone .head-top{border-color:#f8af2d}.plosone .action-label,.plosone .twitter-typeahead .tt-suggestion.tt-cursor,.twitter-typeahead .plosone .tt-suggestion.tt-cursor,.plosone .twitter-typeahead .tt-suggestion:hover,.twitter-typeahead .plosone .tt-suggestion:hover,.plosone .closer-brand,.plosone .nav-pagination .active,.nav-pagination .plosone .active{background-color:#f8af2d;color:#333}.plosone .button,.plosone .button-default,.plosone .nav .nav-user li.highlighted>a,.nav .nav-user .plosone li.highlighted>a{background-color:#f8af2d;color:#333}.plosone .button:hover,.plosone .button-default:hover,.plosone .nav .nav-user li.highlighted>a:hover,.nav .nav-user .plosone li.highlighted>a:hover{background-color:#3c63af;color:#fff}.plosone .article-content .table-download .definition-label{color:#333}.plosone .article-content .figure-inline-download ul li .definition-label a{color:#333}.plosone .article-content .figure-inline-download ul li .definition-label a:hover{text-decoration:none}.plosone #fig-viewer .fv-nav li.tab_active{color:#333}.plosone #fig-viewer-controls .fig-btn{color:#333}.plosone #fig-viewer-controls .fig-btn.next .icn{background-position:-140px 0}.plosone #fig-viewer-controls .fig-btn.next:hover .icn{background-position:-140px -20px}.plosone #fig-viewer-controls .fig-btn.prev .icn{background-position:-130px 0}.plosone #fig-viewer-controls .fig-btn.prev:hover .icn{background-position:-130px -20px}.center-simple{margin:0 auto}.pad-xsmall-x{padding:0 1.25rem}.pad-default-y{padding:18px 0}.margins-reset{margin:0;padding:0}.overlay{background-position:bottom;content:" ";width:100%;height:100%;position:absolute;top:0;left:0}.print-only{display:none!important}@media print{.hide-on-print{display:none!important}.print-only{display:block!important}.hide-for-print,footer,.head-top,.top-bar-section,#user,#topslot{display:none!important}.show-for-print{display:inherit!important}}.dummy-anchor{visibility:hidden}/*!
 * Copyright (c) 2017 Public Library of Science
 *
 * Permission is hereby granted, free of charge, to any person obtaining a
 * copy of this software and associated documentation files (the "Software"),
 * to deal in the Software without restriction, including without limitation
 * the rights to use, copy, modify, merge, publish, distribute, sublicense,
 * and/or sell copies of the Software, and to permit persons to whom the
 * Software is furnished to do so, subject to the following conditions:
 *
 * The above copyright notice and this permission notice shall be included in
 * all copies or substantial portions of the Software.
 *
 * THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
 * IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
 * FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
 * THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
 * LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
 * FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
 * DEALINGS IN THE SOFTWARE.
 */.pill{background:#3c63af;padding:1.25rem;border-radius:5px;color:#fff;display:inline-block}.pill:hover{background:#333}.pill-small{background:#3c63af;padding:.625rem;border-radius:5px;color:#fff;display:inline-block}.button{border-radius:4px;width:auto;padding:.3125rem;height:auto;line-height:1.0625rem;font-size:12px;font-weight:bold;color:#fff}.button-big{background:#333;padding:0 .625rem;border-radius:5px;color:#fff;display:inline-block;line-height:2.1875rem;font-weight:bold;font-size:15px;text-align:center}.button-big:hover{background:#333}.button-big.highlighted{background-color:#3c63af}.button-default{background:#333;padding:0 .625rem;border-radius:5px;color:#fff;display:inline-block;line-height:2.1875rem;font-family:"arial";font-size:14px;text-align:center}.button-default:hover{background:#333}.block{-moz-border-radius-topleft:5px;-webkit-border-top-left-radius:5px;border-top-left-radius:5px;-moz-border-radius-topright:5px;-webkit-border-top-right-radius:5px;border-top-right-radius:5px;padding:.625rem;-webkit-box-shadow:1px 1px 3px 3px rgba(0,0,0,0.15);-moz-box-shadow:1px 1px 3px 3px rgba(0,0,0,0.15);box-shadow:1px 1px 3px 3px rgba(0,0,0,0.15);margin-bottom:1.25rem;background:#fff}.block-noshadow{-moz-border-radius-topleft:5px;-webkit-border-top-left-radius:5px;border-top-left-radius:5px;-moz-border-radius-topright:5px;-webkit-border-top-right-radius:5px;border-top-right-radius:5px;padding:.625rem;margin-bottom:1.25rem;background:#fff}.block-card{padding:0;-webkit-box-shadow:1px 1px 3px 3px rgba(0,0,0,0.15);-moz-box-shadow:1px 1px 3px 3px rgba(0,0,0,0.15);box-shadow:1px 1px 3px 3px rgba(0,0,0,0.15);margin-bottom:1.25rem;background:#fff}.block-dark{border-radius:5px;padding:.625rem;margin-bottom:1.25rem;background:#333}.action-label{display:inline-block;float:left;margin-right:.25rem;border-radius:2px}.tooltip-aside{background:#3c63af;padding:.9375rem .625rem .625rem 1.25rem;border-radius:5px;color:#fff;display:inline-block;padding-right:1.25rem;width:10rem;margin-left:0;display:block}.tooltip-aside .close{position:absolute;top:.3125rem;right:.3125rem}.tooltip-aside li{font-size:16px;font-weight:bold;text-align:left;list-style-type:disc;list-style-position:inside;padding-bottom:.5rem}.tooltip-aside li a{font-weight:bold;color:#fff}.tooltip-aside li a:hover{color:#a7bee9}.reveal-modal-bg{background-color:rgba(0,0,0,0.5)}.twitter-typeahead .tt-menu{background-color:white;min-width:100%;border:1px solid #ccc;border-top-color:transparent;padding:.3125rem 0}.twitter-typeahead h5{font-weight:bold;padding:.3125rem .625rem;margin:0}.twitter-typeahead .tt-suggestion{padding:.3125rem .625rem;margin:0}.twitter-typeahead .tt-suggestion.tt-cursor,.twitter-typeahead .tt-suggestion:hover{cursor:pointer}.pos-right{right:0}.shim{height:50px;position:absolute;width:100%}/*!
 * Copyright (c) 2017 Public Library of Science
 *
 * Permission is hereby granted, free of charge, to any person obtaining a
 * copy of this software and associated documentation files (the "Software"),
 * to deal in the Software without restriction, including without limitation
 * the rights to use, copy, modify, merge, publish, distribute, sublicense,
 * and/or sell copies of the Software, and to permit persons to whom the
 * Software is furnished to do so, subject to the following conditions:
 *
 * The above copyright notice and this permission notice shall be included in
 * all copies or substantial portions of the Software.
 *
 * THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
 * IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
 * FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
 * THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
 * LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
 * FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
 * DEALINGS IN THE SOFTWARE.
 */.more-icon{content:'\f138';padding-left:.1875rem}.icon-fa,.icon-spinner,.icon-twitter,.icon-facebook,.icon-rss,.icon-email,.icon-minus,.icon-plus-no-square,.icon-plus,.icon-close,.icon-alert,.icon-important,.block-important:after,.icon-arrow-right,.icon-arrow-left,.icon-caret-down,.icon-caret-left,.previous-page .icon:before,.icon-caret-right,.level-active li a:not(.no-children)::after,.level-selection .level-scroll a:not(.no-children)::after,.next-page .icon:before,.icon-angle-up,.levels .up,.icon-angle-down,.levels .down,.icon-angle-right,.icon-angle-left,.icon-chevron-left,.levels .prev,.icon-chevron-right,.levels .next,.icon-circle,.icon-times-circle,.icon-pointer,.block-tip:after,.icon-info,.block-more-information:after,.icon-warning,.icon-bell{line-height:44px;font-size:22px}.icon-twitter{content:'\f099'}.icon-facebook{content:'\f09a'}.icon-rss{content:'\f09e'}.icon-email{content:'\f003'}.icon-minus{line-height:normal}.icon-plus-no-square{line-height:normal}.icon-plus{line-height:normal}.icon-close{line-height:normal;content:'\f00d'}.icon-alert{color:#e53350}.icon-important,.block-important:after{content:"\f06a"}.icon-caret-down{font-size:16px;line-height:2.1875rem}.icon-caret-left,.previous-page .icon:before{content:'\f0d9';font-size:16px;line-height:2.1875rem}.icon-caret-right,.level-active li a:not(.no-children)::after,.level-selection .level-scroll a:not(.no-children)::after,.next-page .icon:before{content:'\f0da';font-size:16px;line-height:2.1875rem}.icon-angle-up,.levels .up{font-size:18px;line-height:2.1875rem}.icon-angle-down,.levels .down{font-size:18px;line-height:2.1875rem}.icon-angle-right{font-size:18px;line-height:2.1875rem}.icon-angle-left{font-size:18px;line-height:2.1875rem}.icon-chevron-left,.levels .prev{font-size:26px;line-height:2.1875rem}.icon-chevron-right,.levels .next{font-size:26px;line-height:2.1875rem}.icon-circle{content:'\f111';font-size:10px;line-height:2.1875rem}.icon-question,.icon-question:hover{width:18px;height:18px;background:#3c63af;border-radius:9px;text-align:center;line-height:18px;background-color:#3c63af;color:#fff;display:inline-block;font-size:11px;font-weight:bold;line-height:18px;text-decoration:none}.icon-times-circle{line-height:18px;font-size:20px}.icon-pointer,.block-tip:after{content:"\f0a4"}.icon-info,.block-more-information:after{content:"\f05a"}.icon-warning{font-size:13px;line-height:2.1875rem}.icon-bell{content:'\f0f3'}.list-icon,.list-bullet>li:before,.bulleted>li:before,.menu-icon-right,.level-active li a:not(.no-children)::after,.level-selection .level-scroll a:not(.no-children)::after{position:absolute;top:9px;line-height:0}.aria-text,.switch .icon-text{position:absolute;top:-9999px;left:-9999px}.icon-author-contribute{background:url("../../resource/img/icon.author.co.gif") no-repeat 0 0;vertical-align:middle;display:inline-block;width:.9375rem;height:.8125rem}.icon-author-footnotes{background:url("../../resource/img/icon.author.grp.png") no-repeat 0 0;vertical-align:middle;display:inline-block;width:.9375rem;height:.8125rem}.icon-author-address{background:url("../../resource/img/icon.author.email.png") no-repeat 0 0;vertical-align:middle;display:inline-block;width:.9375rem;height:.8125rem}.icon-correction{background:url("../../resource/img/icon.correction.png") no-repeat 0 0;vertical-align:middle;display:inline-block;width:.9375rem;height:.9375rem}.icon-expand{background:url("../../resource/img/icon.sprite.expand.png") no-repeat 0 0;vertical-align:middle;display:inline-block;width:1.5625rem;height:1.5625rem}.icon-expand:hover{background-position:0 -25px;cursor:pointer}.closer,.tooltip-aside .close,.closer-brand,.top-bar-section .subject-area-info .close,.taxonomy-header #subjInfoText .close{background:url("../../resource/img/icon.sprite.close.png") no-repeat 0 -24px;vertical-align:middle;display:inline-block;width:1.5625rem;height:1.5625rem;color:#fff;text-indent:-9999px}.closer-brand{border-radius:3px}.plosone .closer-brand{background-position:0 0}/*!
 * Copyright (c) 2017 Public Library of Science
 *
 * Permission is hereby granted, free of charge, to any person obtaining a
 * copy of this software and associated documentation files (the "Software"),
 * to deal in the Software without restriction, including without limitation
 * the rights to use, copy, modify, merge, publish, distribute, sublicense,
 * and/or sell copies of the Software, and to permit persons to whom the
 * Software is furnished to do so, subject to the following conditions:
 *
 * The above copyright notice and this permission notice shall be included in
 * all copies or substantial portions of the Software.
 *
 * THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
 * IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
 * FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
 * THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
 * LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
 * FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
 * DEALINGS IN THE SOFTWARE.
 */form fieldset{border:0 none;margin:0;padding:0}/*!
 * Copyright (c) 2017 Public Library of Science
 *
 * Permission is hereby granted, free of charge, to any person obtaining a
 * copy of this software and associated documentation files (the "Software"),
 * to deal in the Software without restriction, including without limitation
 * the rights to use, copy, modify, merge, publish, distribute, sublicense,
 * and/or sell copies of the Software, and to permit persons to whom the
 * Software is furnished to do so, subject to the following conditions:
 *
 * The above copyright notice and this permission notice shall be included in
 * all copies or substantial portions of the Software.
 *
 * THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
 * IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
 * FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
 * THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
 * LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
 * FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
 * DEALINGS IN THE SOFTWARE.
 *//*!
 * Copyright (c) 2017 Public Library of Science
 *
 * Permission is hereby granted, free of charge, to any person obtaining a
 * copy of this software and associated documentation files (the "Software"),
 * to deal in the Software without restriction, including without limitation
 * the rights to use, copy, modify, merge, publish, distribute, sublicense,
 * and/or sell copies of the Software, and to permit persons to whom the
 * Software is furnished to do so, subject to the following conditions:
 *
 * The above copyright notice and this permission notice shall be included in
 * all copies or substantial portions of the Software.
 *
 * THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
 * IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
 * FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
 * THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
 * LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
 * FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
 * DEALINGS IN THE SOFTWARE.
 */footer{padding:1.5625rem 0 3.75rem;color:#ccc}footer .logo-footer{padding-bottom:1.5625rem}footer a,footer a:visited,footer a:focus,footer a:active{color:#ccc;text-decoration:none}footer a:hover,footer a a:hover,footer a:hover a,footer a:visited:hover,footer a:visited a:hover,footer a:visited:hover a,footer a:focus:hover,footer a:focus a:hover,footer a:focus:hover a,footer a:active:hover,footer a:active a:hover,footer a:active:hover a{color:#ccc;text-decoration:underline}footer a .nav,footer a:visited .nav,footer a:focus .nav,footer a:active .nav{position:relative}footer .nav-aux{margin-top:4.6875rem;margin-left:0}footer .nav-aux li{margin-left:.625rem;padding:0 .625rem 0 0;border-right:1px solid #ccc}footer .nav-aux li:first-child{margin-left:0}footer .nav-aux li:last-child{padding-right:none;border-right:0}footer ul{list-style:none;padding-left:0;margin-left:0}.nav-special{font-size:12px}.nav-special a{font-weight:bold;color:#fff}/*!
 * Copyright (c) 2017 Public Library of Science
 *
 * Permission is hereby granted, free of charge, to any person obtaining a
 * copy of this software and associated documentation files (the "Software"),
 * to deal in the Software without restriction, including without limitation
 * the rights to use, copy, modify, merge, publish, distribute, sublicense,
 * and/or sell copies of the Software, and to permit persons to whom the
 * Software is furnished to do so, subject to the following conditions:
 *
 * The above copyright notice and this permission notice shall be included in
 * all copies or substantial portions of the Software.
 *
 * THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
 * IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
 * FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
 * THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
 * LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
 * FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
 * DEALINGS IN THE SOFTWARE.
 */header{background:#efefef}.head-top{border-bottom-width:6px;border-bottom-style:solid;padding:.3125rem .625rem}.head-top .advertisement{float:left}.head-top .center{width:748px;margin:0 auto;height:90px}.head-top .title{width:18px;height:88px;text-indent:-9999px;background:url("../../resource/img/text.vert.ad.gif") no-repeat 0 6px;float:left}.nav .nav-user{font-weight:bold}.nav .nav-user>li{margin-top:-0.3125rem;margin-left:.25rem}.nav .nav-user>li>a{background:transparent;padding:.875rem 1rem .5rem;border-radius:5px;color:#fff;display:inline-block;color:#3c63af}.nav .nav-user>li>a:hover{background:#333}.nav .nav-user>li>a:hover{color:#fff;background:#3c63af}.nav .nav-user li.highlighted>a{color:#fff}body.plosone .nav .nav-user li.highlighted>a{color:#3c63af}body.plosone .nav .nav-user li.highlighted>a:hover{color:#fff}.logo{width:20.41667rem;float:left;margin-left:.625rem;margin-right:.625rem;text-indent:-9999px;height:2.5625rem;background:url("../../resource/img/logo.png") no-repeat 0 0}.logo a{display:block;height:100%}.plosone header .logo,.plosntd header .logo,.plosbiology header .logo{margin-top:-0.5625rem;height:3.625rem}.nav-main{margin-bottom:1.25rem;font-family:"Open Sans",Arial,Helvetica,sans-serif}.nav-main>.dropdown{visibility:hidden}.top-bar-section{width:40.83333rem;float:left;width:40.83333rem}.top-bar-section ul.nav-elements .menu-section-header{font-family:"Open Sans",Arial,Helvetica,sans-serif;font-size:20px}.top-bar-section ul.nav-elements .menu-section li>a,.top-bar-section .dropdownanchor,.top-bar-section ul>li.has-dropdown.hover ul.dropdown li a{width:100%;padding:.25rem 1.5625rem!important;font-size:14px;white-space:pre-wrap}.top-bar-section ul.nav-elements .menu-section li>a:hover,.top-bar-section .dropdownanchor:hover,.top-bar-section ul>li.has-dropdown.hover ul.dropdown li a:hover{color:#fff;background:#3c63af}.top-bar-section h2,.top-bar-section h3{font-family:"Open Sans",Arial,Helvetica,sans-serif;font-size:20px}.top-bar-section .dropdown li{background:#fff}.top-bar-section ul.nav-elements{padding-right:0}.top-bar-section ul.nav-elements>li{margin-left:.1875rem;line-height:2.5rem;padding:0 .9375rem}.top-bar-section ul.nav-elements ul.dropdown li a,.top-bar-section ul.nav-elements ul.dropdowncallout li a{line-height:1.5em!important}.top-bar-section ul.nav-elements>li{float:left}.top-bar-section ul.nav-elements>li:last-child{border-right:1px solid #efefef;padding-right:0}.top-bar-section ul.nav-elements>li:first-child{border-left:1px solid transparent;margin-left:0}.top-bar-section ul.nav-elements .menu-section-header{color:#3c63af;cursor:pointer;border-left:1px solid #ccc}.top-bar-section ul.nav-elements .menu-section-header:first-child{border-left:none}.top-bar-section ul.nav-elements .menu-section li{padding:0;margin-bottom:0}.top-bar-section ul.nav-elements .subject-area{border:0;margin-left:1.5625rem;padding-bottom:.1875rem;background-color:#ccc}.top-bar-section ul.nav-elements .mega .menu-section-header-title{margin-left:.9375rem;margin-bottom:18px;display:block;color:#333;cursor:default}.top-bar-section ul.nav-elements .mega .menu-section li>a{padding-left:.9375rem!important}.top-bar-section ul.nav-elements .mega #submissions .menu-section-header-title{margin-left:1.5625rem}.top-bar-section ul.nav-elements .mega #submissions .menu-section li>a{padding-left:1.5625rem!important}.top-bar-section .subject-area-info{top:0;height:0;position:absolute;margin-top:1.25rem;opacity:0;visibility:hidden;z-index:-1;transition:opacity 300ms ease-out;background:#3c63af;padding:.3125rem;border-radius:5px;color:#fff;display:inline-block;padding-right:1.25rem;width:21.875rem;margin-left:0;top:-50px;left:-60%;text-align:center;font-size:13px;background-color:#fff;color:#707070;font-family:"arial";width:350px}.top-bar-section .subject-area-info.visible{opacity:1;z-index:68;visibility:visible;height:auto}.top-bar-section .subject-area-info .close{position:absolute;top:.3125rem;right:.3125rem}.top-bar-section .subject-area-info:after{content:'\A';top:100%;left:50%;border:solid transparent;content:" ";height:0;width:0;position:absolute;pointer-events:none;border-top-color:#fff;border-width:.5rem;margin-left:-rem-calc($arrow-size)}.top-bar-section ul>li.has-dropdown.hover{-moz-border-radius-topleft:5px;-webkit-border-top-left-radius:5px;border-top-left-radius:5px;-moz-border-radius-topright:5px;-webkit-border-top-right-radius:5px;border-top-right-radius:5px;box-shadow:-3px 3px 3px rgba(0,0,0,0.15),3px 3px 3px rgba(0,0,0,0.15);background:#fff;color:#333}.top-bar-section ul>li.has-dropdown.hover:hover+li{border-left:1px solid #e3e3e3}.top-bar-section ul>li.has-dropdown.hover>.dropdown{top:2.5rem;-webkit-border-radius:5px;-moz-border-radius:5px;-ms-border-radius:5px;-o-border-radius:5px;border-radius:5px;width:15rem;left:-13px;padding-top:1.25rem;padding-bottom:1.875rem;background:#fff;box-shadow:-3px 3px 3px rgba(0,0,0,0.15),3px 3px 3px rgba(0,0,0,0.15)}.top-bar-section ul>li.has-dropdown.hover .mega{width:61.25rem;left:-37.125rem;position:relative;padding-bottom:0}body.plosone .top-bar-section ul>li.has-dropdown.hover .mega{left:-30rem}.top-bar-section ul>li.has-dropdown.hover ul.multi-col{display:table;background:#fff;margin:0;margin-bottom:.625rem}.top-bar-section ul>li.has-dropdown.hover ul.multi-col>li{display:table-cell;width:33%;margin-right:0;margin-left:0;float:none;height:100%}.top-bar-section ul>li.has-dropdown.hover ul.multi-col>li a{padding-left:0}.top-bar-section ul>li.has-dropdown.hover ul.multi-col>li>ul{margin:0}.top-bar-section .calloutcontainer{width:100%;bottom:0;padding:1.5625rem;background:#333;cursor:default;-moz-border-radius-bottomleft:5px;-webkit-border-bottom-left-radius:5px;border-bottom-left-radius:5px;-moz-border-radius-bottomright:5px;-webkit-border-bottom-right-radius:5px;border-bottom-right-radius:5px}.top-bar-section .calloutcontainer h3,.top-bar-section .calloutcontainer p{color:#fff}.top-bar-section .calloutcontainer h3{font-size:26px;font-weight:normal}.top-bar-section .calloutcontainer .callout-content{height:auto;font-family:"arial";font-size:18px;line-height:1.3;float:left;width:42.5rem}.plosone .top-bar-section .calloutcontainer .callout-content{font-size:16px}.top-bar-section .calloutcontainer .callout-content a{background:none!important;color:#89a0d0;text-decoration:none}.top-bar-section .calloutcontainer .callout-content a:hover,.top-bar-section .calloutcontainer .callout-content a a:hover,.top-bar-section .calloutcontainer .callout-content a:hover a{color:#89a0d0;text-decoration:underline}.top-bar-section .calloutcontainer .button-contain{float:right;width:14.6875rem;text-align:right;white-space:nowrap;height:2.1875rem}.top-bar-section .calloutcontainer .button-contain a{padding-top:0;padding-bottom:0;vertical-align:middle;align-items:center;display:inline-flex}.top-bar-section .calloutcontainer .button-contain a.button{top:0}.top-bar-section .calloutcontainer .button-contain a.button-link{font-family:"Open Sans",Arial,Helvetica,sans-serif;font-size:18px;background:#333!important;white-space:nowrap;margin-left:.625rem;vertical-align:middle;line-height:35px}.top-bar-section .calloutcontainer .button-contain a.button-link:hover{background:#333!important;color:#3c63af}.top-bar-section .head-search{padding-top:2px;padding-left:1.25rem;padding-right:0;text-align:right;border-left:1px solid #efefef}.top-bar-section .head-search form{background:#fff;display:inline-block}.top-bar-section .head-search form input:focus,.top-bar-section .head-search form select:focus,.top-bar-section .head-search form textarea:focus,.top-bar-section .head-search form button:focus{outline:0}.top-bar-section .head-search form legend,.top-bar-section .head-search form label{display:none}.top-bar-section .head-search form fieldset{border:0;margin:0;padding:0 .625rem;background-color:#fff}.top-bar-section .head-search form input[type="text"]{margin:0;padding:0;border:0;display:inline-block;width:9.375rem;font-family:"Open Sans",Arial,Helvetica,sans-serif;font-size:20px;color:#666;top:0!important}.top-bar-section .head-search form ::-webkit-input-placeholder{color:#333}.top-bar-section .head-search form :-moz-placeholder{color:#333}.top-bar-section .head-search form ::-moz-placeholder{color:#333}.top-bar-section .head-search form :-ms-input-placeholder{color:#333}.top-bar-section .head-search form.placeholder ::-webkit-input-placeholder{color:#999}.top-bar-section .head-search form.placeholder :-moz-placeholder{color:#999}.top-bar-section .head-search form.placeholder ::-moz-placeholder{color:#999}.top-bar-section .head-search form.placeholder :-ms-input-placeholder{color:#999}.top-bar-section .head-search form button[type="submit"]{background:#fff;border-left:none;color:#333;border-color:#ccc;padding:0;margin:0;border:0;display:inline-block;top:0!important}.top-bar-section .head-search form button[type="submit"] .search-icon{font-size:1.25rem}.top-bar-section ul>li.head-search:not(.has-form)>a{line-height:32px;padding:0;font-size:.8125rem;color:#3c63af;text-decoration:none}.top-bar-section ul>li.head-search:not(.has-form)>a:hover,.top-bar-section ul>li.head-search:not(.has-form)>a a:hover,.top-bar-section ul>li.head-search:not(.has-form)>a:hover a{color:#3c63af;text-decoration:none}.top-bar-section ul>li.head-search:hover:not(.has-form)>a{background:#efefef;color:#3c63af}/*!
 * Copyright (c) 2017 Public Library of Science
 *
 * Permission is hereby granted, free of charge, to any person obtaining a
 * copy of this software and associated documentation files (the "Software"),
 * to deal in the Software without restriction, including without limitation
 * the rights to use, copy, modify, merge, publish, distribute, sublicense,
 * and/or sell copies of the Software, and to permit persons to whom the
 * Software is furnished to do so, subject to the following conditions:
 *
 * The above copyright notice and this permission notice shall be included in
 * all copies or substantial portions of the Software.
 *
 * THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
 * IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
 * FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
 * THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
 * LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
 * FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
 * DEALINGS IN THE SOFTWARE.
 */.areas{background:#2b2b2b}.areas .wrapper{width:60rem;padding:.9375rem 0 1.875rem;margin:0 auto}.menu-icon-right,.level-active li a:not(.no-children)::after,.level-selection .level-scroll a:not(.no-children)::after{top:54%;right:.5rem}#taxonomy-browser{display:none}.taxonomy-header{color:#fff;font-size:18px;font-weight:bold;background:url("../../resource/img/icon-subjAreas.png") no-repeat;height:1.875rem;padding-left:2.0625rem;margin:.625rem auto 2.1875rem .5rem;line-height:1.875rem}.taxonomy-header #subjInfoText{background:#3c63af;padding:.625rem;border-radius:5px;color:#fff;display:inline-block;padding-right:1.25rem;width:25rem;margin-left:0;display:none;position:relative;top:-1.5625rem;left:12.625rem;padding-left:1.25rem;z-index:50}.taxonomy-header #subjInfoText .close{position:absolute;top:.3125rem;right:.3125rem}.taxonomy-header #subjInfoText:hover{display:block}.taxonomy-header #subjInfoText a{font-weight:bold}.taxonomy-header #subjInfo{width:18px;height:18px;background:#3c63af;border-radius:9px;text-align:center;line-height:18px;display:inline-block;font-size:12px;position:relative;left:.4375rem;top:-0.125rem;line-height:18px;z-index:60}.taxonomy-header #subjInfo:hover+#subjInfoText{display:block}.levels .next,.levels .prev{color:#fff;line-height:2.75rem;display:none;width:2.1875rem;height:2.5625rem;position:absolute;top:7.5rem;text-align:center;cursor:pointer}.levels .next:hover,.levels .prev:hover{background-color:#efefef}.levels{padding-left:2.5625rem;position:relative}.levels .next{left:57.5rem}.levels .next:before{content:"\f054"}.levels .prev{left:0}.levels-container{width:54.5rem;height:16.125rem;overflow:hidden;position:relative}.touch .levels-container{overflow-x:auto}.levels-position{width:99999px;position:absolute}.level,.level-top{float:left;width:17.875rem;height:12.8125rem;font-weight:bold;color:#666;margin-right:.4375rem;position:relative}.level ul,.level-top ul{font-size:14px;width:17.875rem;margin:0}.level ul li a,.level-top ul li a{display:block;position:relative;width:100%;padding:.5625rem .9375rem}.no-touch .level .level-scroll li:hover,.no-touch .level-top .level-scroll li:hover{background:#3c63af}.no-touch .level .level-scroll a:hover,.no-touch .level-top .level-scroll a:hover{color:#fff}.level-scroll{width:17.875rem;height:9.875rem;overflow:hidden;background:#efefef}.level-scroll a{text-decoration:none;color:#333}.level-title{font-size:14px;margin-bottom:.5625rem}.level-top{float:none;background-color:#efefef;height:1.875rem;margin-bottom:.4375rem;line-height:1.875rem;font-size:14px}.level-top a{display:block;position:relative;width:100%;color:#333;padding-left:.9375rem}.touch .level-scroll{overflow:auto}.level-active .level-top{background-color:#f8af2d}.level-active .level-title{color:#f8af2d}.levels .up,.levels .down{width:17.875rem;height:1.25rem;text-align:center;background-color:#efefef;line-height:1.25rem;color:#000}a.hide-active-scroll{cursor:default}a.hide-active-scroll:hover{cursor:default}a.hide-active-scroll::before{color:#efefef}.level-selection .level-scroll,.level-selection .level-top{border:1px solid #333;background:#333}.level-selection .hide-active-scroll::before{color:#333}.level-selection .level-title{color:#ccc}.level-selection .level-top a{color:#a0a0a0}.level-selection .up,.level-selection .down{background:#333;color:#a0a0a0}.level-selection .level-scroll a{color:#a0a0a0}.level-selection .level-scroll li.active a{color:#fff}.level-selection .level-scroll li.active{background:#3c63af}.taxonomy-browser-border-bottom{width:100%;height:1.3125rem;background:#efefef}div.inlinePopup{display:none;position:fixed;box-sizing:content-box;top:50%;left:50%;width:400px;height:180px;border:solid 1px #c8dfed;padding-bottom:16px;font:85% Verdana,Arial,Helvetica,sans-serif;background:#fff;z-index:99999}div.inlinePopup input[type="button"].primary{background:#f8af2d;color:#333}div#journal-alert-box.journalAlert{height:150px}div#login-box.login{height:110px}div.inlinePopup div.top-header{position:absolute;width:100%;height:40px;background-color:#333;color:#fff}div.inlinePopup span.heading{font-weight:bold;font-size:14px;position:absolute;left:20px;top:10px}div.inlinePopup div.body-wrapper{position:absolute;top:40px;bottom:40px;padding-left:20px;padding-top:10px;padding-bottom:10px;font-size:12px}div.inlinePopup .big-box{width:350px;border:solid 1px #606060}div.inlinePopup div.check-box{padding-top:4px;width:370px;overflow:hidden;text-overflow:ellipsis;white-space:nowrap}div.inlinePopup div.grey-text{color:#606060;margin-top:8px;width:370px}div.inlinePopup div.button-wrapper{margin-top:10px;cursor:pointer}div.inlinePopup span.errortext{color:#f00}div.inlinePopup input[type="button"]{background:#333;color:#fff;margin-right:2px;padding:9px 10px;border:0;display:inline-block;border-radius:4px;font-weight:bold;text-align:center}div.inlinePopup input[type="button"]:hover{background:#3c63af!important;color:#fff!important}#mask{display:none;background:#000;position:fixed;left:0;top:0;width:100%;height:100%;opacity:.7;z-index:999}/*!
 * Copyright (c) 2017 Public Library of Science
 *
 * Permission is hereby granted, free of charge, to any person obtaining a
 * copy of this software and associated documentation files (the "Software"),
 * to deal in the Software without restriction, including without limitation
 * the rights to use, copy, modify, merge, publish, distribute, sublicense,
 * and/or sell copies of the Software, and to permit persons to whom the
 * Software is furnished to do so, subject to the following conditions:
 *
 * The above copyright notice and this permission notice shall be included in
 * all copies or substantial portions of the Software.
 *
 * THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
 * IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
 * FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
 * THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
 * LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
 * FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
 * DEALINGS IN THE SOFTWARE.
 */.nav-pagination a{line-height:1.5rem;padding:0 .25rem;box-sizing:content-box;color:#333}.number,.switch,.skip{display:inline-block;font-weight:bold;font-size:14px;line-height:1.25rem;padding:0 .375rem;min-width:1rem;border-radius:5px;background-color:#ccc;text-align:center;margin:0 .0625rem}.switch{background:#333;padding:0}.switch.previous-page{margin:0 3.125rem 0 0;padding:0}.switch.next-page{margin:0 0 0 3.125rem;padding:0}.switch.disabled{background-color:#ccc;cursor:default}.switch .icon:before{width:24px;line-height:24px;white-space:nowrap;color:#fff}.previous-page .icon:before{margin-left:-2px}.edboard main{margin-top:2.25rem;margin-bottom:2.25rem}.editors-search-filter{width:100%;display:table;position:relative;margin-bottom:1.125rem}.editors-search-filter label,.editors-search-filter .twitter-typeahead,.editors-search-filter .editors-search-button,.editors-search-filter #loading{float:left;margin-right:.625rem}.editors-search-filter label{font-weight:bold}.editors-search-filter .twitter-typeahead{margin-top:-0.1875rem}.editors-search-filter #editors-search-input{font-size:13px;min-width:14.375rem;padding-right:1.25rem}.editors-search-filter #loading{color:#707070;font-size:1rem;line-height:1;display:none}.editors-search-filter .editors-search-reset{border:0;width:1.125rem;height:1.125rem;background:#666;color:#fff;position:absolute;top:0;left:18.9375rem;padding:0;display:none;border-radius:.1875rem}.results{margin-bottom:1.125rem}.results .counters{margin-bottom:1.125rem}.results .nav-pagination{width:100%;text-align:center;margin-bottom:1.125rem}.results .nav-pagination a,.results .nav-pagination span{display:inline-block}.results .nav-pagination a.previous-page,.results .nav-pagination span.previous-page{float:left}.results .nav-pagination a.next-page,.results .nav-pagination span.next-page{float:right}.results .editors-list li{margin-bottom:1.125rem}.results .editors-list li:last-of-type{margin-bottom:1.6875rem}