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Ubiquitin ligases

MARCH family E3 ubiquitin ligases selectively target and degrade cadherin family proteins

Tadahiko Seo, Anthony M. Lowery, Haifang Xu, William Giang, Sergey M. Troyanovsky, Peter A. Vincent, Andrew P. Kowalczyk

published 09 May 2024

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The CRL4^VPRBP(DCAF1) E3 ubiquitin ligase directs constitutive RAG1 degradation in a non-lymphoid cell line

N. Max Schabla, Patrick C. Swanson

published 14 Oct 2021

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Genetic ablation of Cullin-RING E3 ubiquitin ligase 7 restrains pressure overload-induced myocardial fibrosis

Melanie Anger, Florian Scheufele, Deepak Ramanujam, Kathleen Meyer, Hidehiro Nakajima, Loren J. Field, Stefan Engelhardt, Antonio Sarikas

published 22 Dec 2020

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Preoperative myocardial expression of E3 ubiquitin ligases in aortic stenosis patients undergoing valve replacement and their association to postoperative hypertrophy

Fábio Trindade, Francisca Saraiva, Simon Keane, Adelino Leite-Moreira, Rui Vitorino, Homa Tajsharghi, Inês Falcão-Pires

published 18 Sep 2020

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An Angelman syndrome substitution in the HECT E3 ubiquitin ligase C-terminal Lobe of E6AP affects protein stability and activity

Steven A. Beasley, Chloe E. Kellum, Rachel J. Orlomoski, Feston Idrizi, Donald E. Spratt

published 08 Jul 2020

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Interaction between the cellular E3 ubiquitin ligase SIAH-1 and the viral immediate-early protein ICP0 enables efficient replication of Herpes Simplex Virus type 2 in vivo

Julia S. Czechowicz, Claus-Henning Nagel, Maike Voges, Michael Spohn, Martha M. Eibl, Joachim Hauber

published 06 Aug 2018

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Ubiquitination of alpha-synuclein filaments by Nedd4 ligases

Thomas Mund, Masami Masuda-Suzukake, Michel Goedert, Hugh R. Pelham

published 18 Jul 2018

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Sec16A, a key protein in COPII vesicle formation, regulates the stability and localization of the novel ubiquitin ligase RNF183

Yan Wu, Xiao Peng Guo, Soshi Kanemoto, Yujiro Maeoka, Atsushi Saito, Rie Asada, Koji Matsuhisa, Yosuke Ohtake, Kazunori Imaizumi, Masayuki Kaneko

published 04 Jan 2018

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Identification of the ER-resident E3 ubiquitin ligase RNF145 as a novel LXR-regulated gene

Emma C. L. Cook, Jessica K. Nelson, Vincenzo Sorrentino, Duco Koenis, Martina Moeton, Saskia Scheij, Roelof Ottenhoff, Boris Bleijlevens, Anke Loregger, Noam Zelcer

published 23 Feb 2017

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The pineal gland: A model for adrenergic modulation of ubiquitin ligases

Jerry Vriend, Wenjun Liu, Russel J. Reiter

published 17 Feb 2017

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Regulation of NUB1 Activity through Non-Proteolytic Mdm2-Mediated Ubiquitination

Thomas Bonacci, Stéphane Audebert, Luc Camoin, Emilie Baudelet, Juan-Lucio Iovanna, Philippe Soubeyran

published 18 Jan 2017

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DUB3 Deubiquitylating Enzymes Regulate Hippo Pathway Activity by Regulating the Stability of ITCH, LATS and AMOT Proteins

Hung Thanh Nguyen, Jan-Michael Kugler, Stephen M. Cohen

published 06 Jan 2017

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E2-EPF UCP Possesses E3 Ubiquitin Ligase Activity via Its Cysteine 118 Residue

Jung Hwa Lim, Hee Won Shin, Kyung-Sook Chung, Nam-Soon Kim, Ju Hee Kim, Hong-Ryul Jung, Dong-Soo Im, Cho-Rok Jung

published 29 Sep 2016

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