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Correction

Correction: Identification and characterization of novel TRPM1 autoantibodies from serum of patients with melanoma-associated retinopathy

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The following information is missing from the Funding statement: JV, NB, JW, CZ, IA, JAS: IHU FOReSIGHT (ANR-18-IAHU-0001) supported by French state funds managed by the Agence Nationale de la Recherche within the Investissements d'Avenir program.

The legends for Figs 1 and 3 mistakenly appear in the body of the article. There is an error in the legend for panel B of Fig 4. Please see the complete, correct legends for Figs 1, 3 and 4 here.

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Fig 1. Full-field ERG recordings (DA 3.0).

Ff-ERG responses to a 3.0 cd.s.m2 flash under dark-adapted (DA) conditions from an unaffected subject and the three patients with a clinical diagnosis of melanoma-associated retinopathy (MAR). All three patients had a severely reduced b-wave with an electronegative response.

https://doi.org/10.1371/journal.pone.0233424.g001

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Fig 3. Western blot analysis of TRPM1 isoforms with MAR sera.

Immuno blots of COS-7 cells transfected with the three isoforms of TRPM1 using several antibodies: an anti-TRPM1 antibody, an anti-V5 antibody, MAR1 and MAR2 sera, MAR3 sera after immunoprecipitation using an anti-V5 antibody and a control serum. All antibodies recognized the 70+TRPM1, 92+TRPM1 and 109+TRPM1 isoforms (~180-200kDa). No signal was obtained with protein extracted from untransfected cells.

https://doi.org/10.1371/journal.pone.0233424.g002

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Fig 4. Immunolocalization on Trpm1+/+ and Trpm1-/- mouse retinal cryosections.

(A) TRPM1 (red) staining colocalized (yellow, merge) with MAR1 (green) in Trpm1+/+ and both staining were absent in Trpm1-/- mouse. (B) TRPM1 (red) staining colocalized (yellow, merge) with MAR2 (green) in Trpm1+/+ and both staining were absent in Trpm1-/- mouse. (C) TRPM1 (red) staining colocalized (yellow, merge) with MAR3 (green) in Trpm1+/+ and both staining were absent in Trpm1-/- mouse. (D) TRPM1 (red) staining was present in Trpm1+/+ and absent in Trpm1-/ -mice. Control serum did not reveal any staining. Scale bars: 10μm.

https://doi.org/10.1371/journal.pone.0233424.g003

The citation for reference 20 is incomplete. The complete reference is: McCulloch DL, Marmor MF, Brigell MG, Hamilton R, Holder GE, et al. (2015) ISCEV Standard for full-field clinical electroretinography (2015 update). Doc Ophthalmol 130: 1–12. pmid: 25502644

The publisher apologize for the errors.

Reference

  1. 1. Varin J, Reynolds MM, Bouzidi N, Tick S, Wohlschlegel J, Becquart O, et al. (2020) Identification and characterization of novel TRPM1 autoantibodies from serum of patients with melanoma-associated retinopathy. PLoS ONE 15(4): e0231750. https://doi.org/10.1371/journal.pone.0231750 pmid:32324760

Citation: The PLOS ONE Staff (2020) Correction: Identification and characterization of novel TRPM1 autoantibodies from serum of patients with melanoma-associated retinopathy. PLoS ONE 15(5): e0233424. https://doi.org/10.1371/journal.pone.0233424

Published: May 13, 2020

Copyright: © 2020 The PLOS ONE Staff. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.