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Correction: Treatment combining aliskiren with paricalcitol is effective against progressive renal tubulointerstitial fibrosis via dual blockade of intrarenal renin

  • Sungjin Chung,
  • Soojeong Kim,
  • Minyoung Kim,
  • Eun Sil Koh,
  • Seok Joon Shin,
  • Cheol Whee Park,
  • Yoon Sik Chang,
  • Ho-Shik Kim

Correction: Treatment combining aliskiren with paricalcitol is effective against progressive renal tubulointerstitial fibrosis via dual blockade of intrarenal renin

  • Sungjin Chung, 
  • Soojeong Kim, 
  • Minyoung Kim, 
  • Eun Sil Koh, 
  • Seok Joon Shin, 
  • Cheol Whee Park, 
  • Yoon Sik Chang, 
  • Ho-Shik Kim
PLOS
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There are errors in Figs 1 and 3. The authors have provided corrected versions here.

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Fig 1. Greater beneficial effect of combination treatment with aliskiren and paricalcitol on renal fibrosis in the obstructed kidney.

(A) Representative renal sections stained with Masson-trichrome (original magnifications, x200). (B) Quantitative analysis of the results for fibrotic area in the renal tubulointerstitium. *P<0.001 versus UUO; **P = 0.001 versus UUO; #P<0.001 versus UUO+A or UUO+P.

https://doi.org/10.1371/journal.pone.0196885.g001

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Fig 3. Synergistic effect of combination treatment with aliskiren and paricalcitol on the expression of myofibroblasts in the obstructed kidney.

(A) Representative renal sections stained with α-SMA(original magnification, x200). (B) Quantitative analysis of the results for α-SMA in the renal tubulointerstitium. *P<0.001 versus UUO; **P = 0.001 versus UUO; #P = 0.001 versus UUO+A and P<0.001 versus UUO+P. α-SMA, α-smooth muscle actin.

https://doi.org/10.1371/journal.pone.0196885.g002

Reference

  1. 1. Chung S, Kim S, Kim M, Koh ES, Shin SJ, Park CW, et al. (2017) Treatment combining aliskiren with paricalcitol is effective against progressive renal tubulointerstitial fibrosis via dual blockade of intrarenal renin. PLoS ONE 12(7): e0181757. https://doi.org/10.1371/journal.pone.0181757 pmid:28753620