Kinematic information during impact was captured using a high-speed camera at a rate of 1200 frames/s. The impact force was measured using the miniature load cell that was fixed to the central portion of the skull vault of the rat. The linear acceleration response of the rat head was recorded using a modified accelerometer.
Behavioral tests including mNSS and beam walking tests were performed before lesion and on days 1, 4, and 7 post-lesion. Western blotting tests were performed on days 1 and 7 post-lesion to quantify the injury severity following weight-drop-induced head injury.
Citation: Hsieh T-H, Kang J-W, Lai J-H, Huang Y-Z, Rotenberg A, Chen K-Y, et al. (2017) Correction: Relationship of mechanical impact magnitude to neurologic dysfunction severity in a rat traumatic brain injury model. PLoS ONE 12(7): e0182300. https://doi.org/10.1371/journal.pone.0182300
Published: July 24, 2017
Copyright: © 2017 Hsieh et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.