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Correction: MSLN gene silencing has an anti-malignant effect on cell lines overexpressing mesothelin deriving from malignant pleural mesothelioma

  • Ombretta Melaiu,
  • Justin Stebbing,
  • Ylenia Lombardo,
  • Elisa Bracci,
  • Norihisa Uehara,
  • Alessandra Bonotti,
  • Alfonso Cristaudo,
  • Rudy Foddis,
  • Luciano Mutti,
  • Roberto Barale,
  • Federica Gemignani,
  • Georgios Giamas,
  • Stefano Landi
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In Fig 4A, the incorrect image is used for siMSLN-1. Please see the correct Fig 4 here.

Fig 4. Role of MSLN in cellular migration and invasion.

A. No effects observed in the wound-healing assay, following siRNA transfections. Confluent monolayers of Mero-14 cells transfected with 40 nM of siCtrl, or siMSLN-1, respectively. Two different experiments were carried out, each performed in triplicate. B. Trans-well cell invasion assay on Mero-14 cells transfected with 40 nM of the siCtrl (top), or siMSLN-1 (bottom). Pictures were taken using a fluorescence microscope at 10X magnification and are reported as negative of the originals to enhance the contrast between the background and the DAPI-stained cells. The bar chart shows the average of invasive cells (error bars represent SEM of two independent experiments, each done in triplicate, *P = 0.0044).


  1. 1. Melaiu O, Stebbing J, Lombardo Y, Bracci E, Uehara N, Bonotti A, et al. (2014) MSLN Gene Silencing Has an Anti-Malignant Effect on Cell Lines Overexpressing Mesothelin Deriving from Malignant Pleural Mesothelioma. PLoS ONE 9(1): e85935. pmid:24465798