In presence of peroxide, ferrous RH are oxidized to their ferric (FeIII) and/or ferryl (FeIV) forms. Upper: Hp binds Hb (ferrous and/or ferric) thereby preventing its release. Lower: Mb heme is retained attached to globin following oxidation in a peroxidase-like form. However, binding of CO to ferrous Mb prevents its oxidation to a ‘peroxidase-like form”.
Citation: The PLOS ONE Staff (2014) Correction: Can Gas Replace Protein Function? CO Abrogates the Oxidative Toxicity of Myoglobin. PLoS ONE 9(10): e111565. https://doi.org/10.1371/journal.pone.0111565
Published: October 15, 2014
Copyright: © 2014 The PLOS ONE Staff. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.