The authors retract this publication due to concerns about the cell lines employed in the study.
The study reports experiments looking at pathways involved in anoikis resistance in human adenoid cystic carcinoma; the experiments involved the use of the cell lines ACCM and ACC2. After the publication of the article, a reader raised concerns that these two cell lines may not originate from adenoid cystic carcinoma. The authors have completed a short tandem repeat analysis on the cell lines and this has revealed cross-contamination with other human cells, which compromises the relevance of the work to human adenoid cystic carcinoma, and thus the conclusions of the study.
In the light of this, the authors retract this publication.
- 1. Jia J, Zhang W, Liu J-Y, Chen G, Liu H, et al. (2012) Epithelial Mesenchymal Transition Is Required for Acquisition of Anoikis Resistance and Metastatic Potential in Adenoid Cystic Carcinoma. PLoS ONE 7(12): e51549
Citation: Jia J, Zhan W, Liu J-Y, Chen G, Liu H, Zhong H-Y, et al. (2014) Retraction: Epithelial Mesenchymal Transition Is Required for Acquisition of Anoikis Resistance and Metastatic Potential in Adenoid Cystic Carcinoma. PLoS ONE 9(9): e108117. https://doi.org/10.1371/journal.pone.0108117
Published: September 10, 2014
Copyright: © 2014 Jia et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.