There are multiple errors in the third paragraph of the Introduction. The third paragraph should read:
"In addition to their bactericidal activities in phagocytic cells, NOX play numerous physiological roles in nonphagocytic cells –. Interestingly, the activities of several factors that influence AQP2 abundance are also modulated by ROS. Notably, NOX2 and NOX4 have been shown to modulate cAMP-PKA signaling in pancreatic β-cells  and endothelial cells , respectively, indicating that these NOX isoforms may influence the transcriptional regulation of PKA-sensitive gene products. NF-κB, which contains redox-sensitive cysteine residues in its DNA binding domain  and whose activity is increased by NOX-derived ROS , reduces AQP2 transcription , . ROS was additionally shown to contribute to activation of tonicity-responsive enhancer binding protein (TonEBP) , which may enhance AQP2 transcription , . All these findings indicate that AQP2 expression may be sensitive to cellular ROS."
Citation: The PLOS ONE Staff (2014) Correction: NADPH Oxidase 4 Deficiency Reduces Aquaporin-2 mRNA Expression in Cultured Renal Collecting Duct Principal Cells via Increased PDE3 and PDE4 Activity. PLoS ONE 9(2): e91395. https://doi.org/10.1371/journal.pone.0091395
Published: February 27, 2014
Copyright: © 2014 The PLOS ONE Staff. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.