Dopaminergic neurons of separate cohorts of mice were counted for 7 month old mice (A) and 18 month old mice (B) and 16 month old mice (C). n = 4 for all genotypes. One-way ANOVA showed no differences between any of the genotypes (p ≥ 0.1). Representative images of TH-stained coronal sections used for analysis are shown for 7 month old wild-type (D), Parkin-/-DJ-1-/- (E), Parkin-/-DJ-1-/-SOD2+/- (F) and Parkin-/-DJ-1-/-SOD1-/- (G).
Hematoxylin and eosin staining of sections of the heart (A, B), the cerebellum (C, D) and the extensor digitorum longus (EDL) muscle (E) appeared normal in Parkin-/-DJ-1-/- (dKO) mice compared to wild type mice. Metachromatic ATPase staining (F) showed comparable distribution of dark blue Type I fibers and lighter blue Type II fibers in soleus muscle from wild type and Parkin-/-DJ-1-/- mice. Scale bar = 100 μm.
Citation: The PLOS ONE Staff (2014) Correction: Behavioral and Neurotransmitter Abnormalities in Mice Deficient for Parkin, DJ-1 and Superoxide Dismutase. PLoS ONE 9(2): e91128. https://doi.org/10.1371/journal.pone.0091128
Published: February 27, 2014
Copyright: © 2014 The PLOS ONE Staff. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.