HPV vaccines are available to men but there are few studies investigating the acceptability of HPV vaccines among men who have sex with men (MSM), a high risk group. We assessed the intention to take up HPV vaccines among MSM in Hong Kong and the associated factors related to cognitions on HPV and HPV vaccines, basing on the Health Belief Model (n = 542). The acceptability of HPV vaccines was 20% (unconditional on efficacies and price), 29.2% (conditional on efficacies and market price), 51.7% (conditional on efficacies and discounted price) and 79.1% (conditional on efficacies and free price). Adjusting for background variables, composite scores of perceived susceptibility, perceived severity, perceived barriers and cue to actions were significantly associated with acceptability of HPV vaccines conditional on specific efficacies and the market price. Acceptability of HPV vaccines was highly price sensitive. Future studies need to use conditional measures. Implementation and translational researches are warranted.
Citation: Lau JTF, Wang Z, Kim JH, Lau M, Lai CHY, Mo PKH (2013) Acceptability of HPV Vaccines and Associations with Perceptions Related to HPV and HPV Vaccines Among Men Who Have Sex with Men in Hong Kong. PLoS ONE 8(2): e57204. https://doi.org/10.1371/journal.pone.0057204
Editor: Clive M. Gray, University of Cape Town, South Africa
Received: June 12, 2012; Accepted: January 23, 2013; Published: February 22, 2013
Copyright: © 2013 Lau et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Funding: This study was funded by the Merck Sharp &Dohme (Asia) Ltd. (Ref: IISP 37671), http://www.hkexporter.net/medicine/merck-sharp.html. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Competing interests: This study was funded by Merck Sharp & Dohme (Asia) Ltd. (MSD ref: IISP 37671). The authors declare that none of the authors served as paid employees, consultants or board members of above mentioned company. No patent has been applied in this study. This does not alter the authors’ adherence to all the PLoS ONE policies on sharing data and materials.
HPV is highly infectious. It causes not only genital warts as a sexually transmitted disease (STD) but also cervical cancer among females and anal/penile cancer among males . Previous studies conducted in the U.S. have documented high prevalence of HPV in the male general population, ranging from 7.9%  to 63.1% . One recent study estimated that the prevalence of genital warts is 0.94% in the Hong Kong male general population, with an estimated incidence of about 300 per 100,000 person-years , which was higher than those estimated in the U.S. and in other countries .
Recent studies have shown that HPV vaccines could effectively prevent genital warts, penile and anal cancers, and reduced high grade anal lesion (HGAIN) among males , , . A number of cost-effectiveness studies have been conducted on HPV vaccination. One recent review study pointed out that “Cost-effectiveness studies indicate that in the context of modest female vaccination rates and with the specification of a broad range of disease outcomes (e.g. genital warts, anogenital cancers, and oropharyngeal cancers), male vaccination can be quite cost-effective” . One cost-effectiveness study pointed out that “The most cost-effective scenario would include vaccinating MSM at age 12 before exposure to HPV; however, vaccination occurring up to age 26, with exposure to all vaccine types assumed to be 50%, was still cost-effective” . Another study also concluded that “Vaccinating boys and men age 9–26 against all HPV 6/11/16/18-associated diseases provides substantial public health benefits and is cost-effective at commonly cited thresholds” .
The U.S. Center for Diseases Control and Prevention (CDC) recommends men who have sex with men (MSM) of age 26 years or younger to take up HPV vaccines , followed by the European Medicines Agency , Society of Physicians of Hong Kong and the Family Planning Association of Hong Kong . Although the recommended age range for males is 9–26 years old, doctors can opt to give it to other men “off license” if they wish and some doctors recommend its use to adult men. One study showed that the quadrivalent HPV vaccine significantly reduced high grade anal lesions (HGAIN) recurrence among MSM of 20–70 years old . In addition, two ongoing clinical trials are investigating the efficacies of HPV vaccines targeting males of age >26 years older , . Although current programs promoting HPV vaccination only target MSM of age < = 26 years old, it is potentially important to understand acceptability of HPV vaccination among MSM of age >26 as it is possible that new researches may find HPV vaccines efficacious among older males.
HPV and HIV infections are closely related to each other, whilst MSM in general greatly concern about HIV. The prevalence of genital and anal warts was 8.9% and 19.6% respectively among Australian HIV-negative homosexual men . A study showed that the prevalence of genital warts was 13.2% among MSM in China . A 61-city study further reported HIV prevalence among MSM in China to be 4.9% , whilst two cohort studies reported high HIV incidences of 4.17 and 5.40 per 100 person-years , . Co-infection of HPV and HIV are consequential . One study showed that carcinoma and anal intraepithelial neoplasia were frequent in HIV-positive men , whilst another study showed that “all HPV-associated cancers in AIDS patients occurred in statistically significant excess compared with the expected numbers of cancers” . Furthermore, some studies showed that anal HPV infection may be associated with HIV acquisition  and that HIV incidences increased significantly with high risk HPV positivity . The potential relationships between HPV and HIV and the concern of HIV among MSM may motivate MSM indirectly to take up HPV vaccination.
Six published studies have investigated acceptability of HPV vaccines among MSM. The prevalence of acceptability ranged from 36% to 86% , , , , , . Only one of these studies mentioned the price of HPV vaccines when asking the question on acceptability . Significant associated factors included perceived susceptibility and perceived severity of HPV-related diseases, perceived effectiveness, benefits and positive attitudes related to the vaccines, belief that a physician would recommend the vaccines to MSM, anticipated regret for contracting HPV without taking up HPV vaccines and number of sex partners. Acceptability studies are important in designing effective HPV vaccination promotion campaigns. None of the aforementioned studies was conducted in China.
Health promotions basing on health behavioral theories are more likely to be effective than non-theory-based interventions . The Health Belief Model (HBM) specifies that the constructs of perceived susceptibility and perceived severity in contracting HPV, perceived benefits, perceived barriers, cue to action and self-efficacy related to taking up HPV vaccines are determinants of HPV vaccination. It has been applied to explain and to promote HPV vaccination among females  and was used in this study to guide variable selection.
We therefore investigated the prevalence of intention to take up HPV vaccination in the next six months among MSM age 18–60 years old in Hong Kong under four scenarios (see Measures) and perceptions related to HPV and HPV vaccines derived from HBM. Associations between acceptability (conditional on efficacies and market rate) and the HPV-related perceptions were also investigated.
Subjects and Methods
Study Population and Data Collection
Inclusion criteria were: 1) Hong Kong Chinese men of 18 to 60 years old and 2) having had oral or anal intercourse with at least one man in the last six months. Participants were recruited from some gay venues (bars and saunas) frequently visited by gay people during September 2010 through January 2011. This method has been used in previous studies , . Recently, a mapping exercise was conducted by the government and identified 12 gay bars and 16 gay saunas in Hong Kong . All these venues were approached by our research staff. Approval was sought from the owners of six of the gay bars and nine of the gay saunas. The venue-based interviews were administered by some experienced peer interviewers at different time slots during weekdays and weekends. They briefed prospective participants about the study and invited them to join the study. Convenience sampling was performed at the venues. A total of 1100 eligible MSM were invited to join the study; 550 refused to participate; 8 participants did not complete the interview; 542 participants (49.3%) provided written informed consent and completed the anonymous face-to-face interview in a setting with privacy ensured. They were given HK$50 (about US$6) for their time spent (about 20 minutes). Ethics approval was obtained from the ethics committee of the Chinese University of Hong Kong.
Participants were asked about their socio-demographic information, sexual orientation, utilization of HIV-related services, history of STD (symptoms and diagnosis), unprotected anal intercourse (UAI) with men and the number of male sex partners with anal intercourse in the last six months (see Table 1). Acceptability was assessed under four scenarios: 1) without mentioning efficacies and price (unconditional), 2) conditional on the efficacies of taking up three shots of HPV vaccines within three months (>90% for prevention of genital warts and 75% for prevention of HPV induced cancers ) and a market price of HK$1000 to 2000 (US$ 128 to 256) per shot for three shots, 3) conditional on the aforementioned efficacies and about half of the market price (HK$500 to 1000; US$64 to 128) per shot for three shots, 4) conditional on the aforementioned efficacies and three free shots.
Questions asked included knowledge and HBM-related cognitions on HPV and HPV vaccines (Tables 2 and 3). Six composite indicator variables were constructed in this study by counting the number of affirmative item responses reflecting the level of perceived susceptibility (ranged from 0 to 3), perceived severity (ranged from 0 to 3), perceived benefits (ranged from 0 to 5), perceived barriers (ranged from 0 to 5), perceived self-efficacy (ranged from 0 to 2) and perceived cue to action (ranged from 0 to 3).
Odds ratios were firstly presented in the univariate analysis (ORu). A multiple stepwise regression model was then fit using the significant univariate background variables as candidates and multivariate odds ratios (ORm) were derived. Associations between the cognitive factors and the dependent variable (acceptability of HPV vaccination conditional on efficacies and market rate) were assessed, adjusting for those background variables that were found to be significant in the multivariate analysis and adjusted odds ratios (AOR) were derived. Corresponding 95% confidence intervals (CI) of odds ratios were presented. SPSS version 16.0 was used for data analysis, with p values of <.05 taken as statistically significant.
About half of the participants (53.4%) were 30 years old or younger; 63.5% had attained colleges; 12.7% were cohabitating with a man; 86.7% considered himself as a homosexual person; 85.4% had utilized HIV prevention services; 10.0% had had some STD symptoms in the past year. The prevalence of UAI (last six months) was 32.3% and the prevalence of multiple male sex partnerships (last six months) was 44.8% (Table 1).
Intention to Take Up HPV Vaccines in the Next Six Month (Acceptability)
The prevalence of acceptability was 20% (unconditional on efficacies and price), 29.2% (conditional on efficacies and the market price), 51.7% (conditional on efficacies and a halved discounted price) and 79.1% (conditional on efficacies and free price). Comparing participants of < = 26 and >26 years old, the differences in prevalence of acceptability of HPV vaccination under the aforementioned four scenarios were not found to be statistically significant. The prevalence of those who were < = 26 years old under the four scenarios was respectively 16.0%, 27.2%, 51.9% and 81.5%, whilst that of those who were >26 years old was respectively 18.9%, 30.0%, 51.6% and 78.2% (p>.05, chi-square test).
Cognitions on HPV
The prevalence of appropriate response for the other individual knowledge items ranged from 24.5% to 58.7% (Table 2). There were hence common misconceptions that HPV would not affect men, that it could be controlled by using antibiotics, that it was a newly found virus, that it was totally curable, that it was hereditary and that it caused a mortality >5% (Table 2). Regarding perceived susceptibility, 40.6% of the participants perceived that the prevalence of HPV infection among MSM in Hong Kong was >10%; 54.6% believed that the infectivity of HPV was high or very high. In contrast, only 6.1% of the participants perceived a high or very high chance of contracting HPV in the future. Item responses reflecting perceived severity (Table 2) were: damages on physical health (51.7%), chance that HPV infection would cause genital warts (63.7%) and chance that HPV infection would cause penile or anal cancer (36.3%).
Cognitions on HPV Vaccines
The prevalence on item responses corresponding to correct knowledge about HPV vaccines (availability, price, the 3-shot requirement, expected duration of protection, preferred age range for vaccination) was low and ranged only from 3.9% to 27.7% (Table 3). The prevalence of responses reflecting perceived benefits of HPV vaccines was: preventing genital warts (67.7%), preventing penile and anal cancers (55.9%), preventing STD other than genital warts (29.2%), treating genital warts (38.2%) and treating penile and anal cancers (17.2%). Concerning perceived barriers, the prevalence of agreement or strong agreement with the statements was: “HPV vaccines are expensive” (55.2%); “there are side effects” (42.4%); “it is embarrassing to take up HPV vaccines” (41.3%); “it is troublesome to take up HPV vaccines” (31.0%) and “HPV vaccination signifies promiscuity” (33.9%). The level of perceived self-efficacy to take up HPV vaccines was high (88.9% and 95.4%). The prevalence of responses reflecting exposure to cue to action was however, very low: media report (6.8%), doctor (2.6%) and peer (3.3%).
Factors Associated with Acceptability of HPV Vaccines (Conditional on Specific efficacies for Disease Prevention and Market Price)
Two of the background variables that were listed in Table 4 were statistically significant: exposure to peer education (ORm = 1.55, 95% CI = 1.02–2.35) and UAI with any male sex partner (ORm = 0.47, 95% CI = 0.30–0.73). Adjusting for these two variables, the results showed that two knowledge variables were of marginal statistical significance (.05<p<.1): “don’t know whether men can be affected by HPV” (AOR = 2.36, 95% CI = 0.93–6.03) and perceived availability of effective HPV vaccines among men (AOR = 1.51, 95% CI = 0.99–2.29; Table 5). Two significant variables related to perceived severity of HPV included: perception that HPV had a high or very high chance of causing genital warts (AOR = 1.61, 95% CI = 1.06–2.43; reference group was “moderate/low/very low chance”) and perceived moderate or high/very high chances that HPV would cause penile/anal cancer (moderate chance: AOR = 3.55, 95% CI = 2.09–6.05; high/very high chance: AOR = 2.72, 95% CI = 1.61–4.60; reference group was “low/very low chance/uncertain”). Perceived efficacy in preventing STD other than genital warts (AOR = 1.69, 95% CI = 1.09–2.61) was the only item reflecting perceived benefits of HPV vaccines that was of statistical significance. Several factors on perceived barriers were significant: concerns on “expensive price” (AOR = 0.63, 95% CI = 0.41–0.97), “side effects” (AOR = 0.63, 95% CI = 0.41–0.98), and “promiscuity” (AOR = 0.38, 95% CI = 0.24–0.60) and some “don’t know” answers (e.g. “it is embarrassing to take up HPV vaccines”). All the three independent variables on perceived cue to action were significant: having obtained advices from the media (AOR = 2.49, 95% CI = 1.25–4.99), from doctors (AOR = 3.12, 95% CI = 1.05–9.30) and from his peers (AOR = 3.82, 95% CI = 1.43–10.21).
Furthermore, the adjusted analysis showed that four of the six HBM-related composite indicator variables (see Measures) on perceived susceptibility (AOR = 1.85 to 2.07, p<.05), perceived barriers (AOR = 0.59, p<.05), perceived cue to action (AOR = 25.99, p<.05), and perceived severity (AOR = 1.89 to 1.94, p<.05) were of statistical significance (Table 6). In addition, we fit a multiple logistic regression model containing all the factors that were listed in Table 6, adjusted for the same significant background variables. Similar results were obtained except that the variable of perceived severity became statistically non-significant, due to its associations with other variables included into the model (data not tabulated).
Like their counterparts in other countries (e.g. ), the sampled MSM were at high risk of contracting HPV as many of them had had STD symptoms, UAI with men and multiple male sex partners. Such observations corroborated with the results obtained from a number of local studies (e.g. ). It was however, unexpected that those who had had UAI were significantly less likely than others to find HPV vaccines acceptable. It is plausible that the motivation to use condoms correlates closely with that of taking up HPV vaccines as both measures are means of HIV/STD prevention. Those who care less about HIV/STD infection would neither use condoms during anal intercourse nor be willing to take up HPV vaccination. A positive association between UAI and lower acceptability of HPV vaccination would then be resulted. Therefore, we cannot expect MSM of higher risk of HIV/STD transmission would naturally become more willing to take up HPV vaccination because of their high risk status and their stronger wish to protect themselves. Instead, interventions to promote HPV vaccination targeting high risk MSM are required to persuade them to adopt this and other preventive measures.
It is known that the cost of the HPV vaccine is a strong determinant of HPV vaccination among females . No study has studied the association between price sensitivity of HPV vaccines and acceptability of HPV vaccines among MSM. Our results showed that acceptability of HPV vaccines varied from about 30% to about 50% if the prices were halved to almost 80% if free vaccines were made available. Our prevalence of acceptablity of HPV vaccines at market price was lower than those reported in the U.S. which did not condition on price, but was comparable to the Australian data which conditioned on price. Our acceptability data conditioned on free vaccines was comparable to or higher than those reported in the U.S. studies. It is important to point out that five of the six existing reports on acceptability of HPV vaccines among MSM had not mentioned price of the vaccines , , , , . The results of such studies were difficult to interpret. A number of acceptability studies on new public health initiatives have found significant differences between conditional and unconditional acceptability . Conditional measures are hence required for acceptability studies. It is also important to lower the cost of HPV vaccination. For public health reasons, some governments have subsidized various types of vaccination among various high risk groups . Previous studies have already proved that HPV vaccination among young MSM is cost effective , consideration should hence be made to provide free or low-cost HPV vaccination to high risk young MSM, such as male sex workers, which may maximize the benefit.
It was found that MSM did not know enough about HPV, as close to half of them possessed misconceptions about HPV (HPV would not affect men; HPV could be controlled by antibiotics; HPV was a newly found virus; HPV is totally curable and HPV is hereditary) and 72.3% of them did not know about availability of HPV vaccination for men. Such knowledge may potentially affect perceived needs to adopt preventive behaviors as it is associated with perceived susceptibility and perceived severity. To promote the newly available HPV vaccines among MSM, we hence need to increase their knowledge about HPV and HPV vaccines (e.g. diseases caused, availability to men, duration of protection and effectiveness), as we found that the knowledge levels were low and some of the HPV-related knowledge variables were significantly associated with acceptability of HPV vaccination.
Four HBM-related composite indicator variables (perceived barriers, perceived susceptibility, perceived severity and cue to action) were significantly associated with acceptability of HPV vaccines. It is important to remove perceived barriers. In this study, cognitive and psychological barriers (perceived side effects, potential embarrassment and worry about the label of promiscuity) instead of logistical barriers (e.g. troublesome to take up the vaccines) were of statistical significance. It is known that worrying about side-effects is a common determinant of acceptability of new vaccines . Furthermore, genital warts and genital/anal cancers may be associated with social stigma, which is prevalent among MSM . Those taking up HPV vaccines may be labeled as being promiscuous . To minimize stigma resulted from HPV vaccination, programs promoting HPV vaccines should be conducted by peer MSM and at NGO that serve MSM; the MSM communities should always be involved to provide advice to the design of such programs. Good doctor-patient communication is also required to reduce embarrassment . The vaccination should also be backed up by MSM-friendly clinics as previous studies have reported discrimination against MSM in health care settings . Therefore, clinical, financial and psycho-social factors all need to be carefully considered when designing effective programs promoting HPV vaccination among MSM.
Perceived susceptibility was another statistically significant factor. Though high percentages of the participants perceived high infectivity of HPV and high prevalence of HPV among local MSM, only about 6% of them perceived a high or very high chance in contracting HPV in the future. This phenomenon of having high perceived risk for others but low perceived risk for oneself in contracting HIV/STD has been reported in previous studies . It is important to increase risk perception of HPV among MSM. Dissemination of data about the high prevalence of HPV among MSM should be a good starting point. Both perceived severity of genital warts and penile/anal cancer were significant factors. Promotion campaigns should emphasize on both diseases. It is uncertain whether focusing only on the cancer factor would suffice. If such is true, hindrance of HPV vaccination due to stigma associated with genital warts could be reduced. Further studies are warranted.
Cue to action is strongly associated with vaccination behaviors . In the Health Belief Model, cue to action is an important determinant of the intention to take up a health-related behavior such as safer sex. In this study, all three types of cues to action (media, doctors, and peers) were significant. Media campaigns have been used effectively to promote HPV among young women . Gay websites may be an important media accessing MSM as the prevalence of internet use among MSM is very high . Involvement of health professionals is always important . Peer education and testimonials may be considered.
Perceived benefit was not significantly associated with acceptability of HPV vaccines. The participants were briefed about the vaccines’ efficacies before they answered the questions on acceptability of HPV vaccines; questions on perceived benefits were asked after the questions on acceptability. The sequence may have reduced the strength of this association. One single item on perceived benefit was significant (“Perceived efficacy in preventing STDs other than genital warts”). Genital warts increase the risk of contracting other types of STD . Promotion campaigns should explain such relationships to MSM. Perceived self-efficacy was also non-significant. This may be explained by the small variation in item responses, as about 90% of the participants perceived a high level of self-efficacy on HPV vaccination.
Promotion of HPV vaccines is warranted and the social context seems favorable for such campaigns. MSM in China, including Hong Kong, tend to be young and well educated. In general, younger age and higher education levels are associated with adoption of preventive behaviors . As recommended by international and local health authorities, HPV vaccines work well for younger men, an important message to be disseminated to MSM. There is a good chance to integrate promotion of HPV vaccination with existing HIV prevention services. About half of the participants had taken up HIV voluntary Counseling and Testing (VCT) and regular VCT is recommended. It is potentially useful to include HPV vaccination as part of the VCT services offered by the government and NGO. The integration may be effective as VCT users may already been motivated to take up HIV protective measures and should be more ready to take up HPV vaccines, as compared to their counterparts who are unwilling to take up VCT. The integration of HPV and HPV vaccination may even attract more MSM to take up VCT as HPV vaccination becomes an added value to existing HIV VCT. Stigma may be less an issue in the context of having VCT provided by peer educators. It is suggested that HIV workers need to be trained about HPV and HPV vaccination. Pilot studies to evaluate effectiveness of promoting HPV vaccination in settings of HIV VCT and other HIV-related service are greatly warranted.
Our sampling method has some limitations. The sample may be subjected to selection bias since no sampling frame existed and convenience sampling involving multiple sources was conducted. We did not recruit participants from the Internet though about half of the local MSM have recruited male sex partners from this source . In addition, we did not systematically collect information about the gay bars and saunas that accepted or refused our invitation to participate the study. The response rate was only about 50% though it is comparable to that of some similar studies . Several other limitations should also be brought to readers’ attention. First, this is a cross-sectional study and causal relationship cannot be established. Second, we asked about behavioral intention rather than actual behaviors. It is expected that the prevalence of HPV vaccination approached zero as HPV vaccines have only been newly available to males. Behavioral intention, an important construct of the Theory of Planned Behaviors , is strongly predictive of health-related behaviors. Third, social desirability may lead to over-reporting of acceptability. The question items were constructed for this study as no validated scale was available. Lastly, the sequence of asking the four conditions of acceptability of HIV vaccination (overall, efficacies and market rate, efficacies and discounted rate, efficacies and free vaccination) may potentially affect the responses to these items. However, since our associated factors were based on acceptability of HPV vaccination at the market rate (asked in the second place), we believe that the effect of the sequence of questions on the reported associations should be acceptable.
In sum, HPV vaccination among MSM is an important public health initiative and promotion is warranted. Such campaigns need to focus on cognitions and knowledge related to HPV and HPV vaccines. To recapitulate, the studies have important implications for designing HPV vaccination programs. Such programs should start with media campaigns promoting knowledge about HPV and HPV vaccination among MSM. The Health Belief Model can be used as a framework to guide design of such programs as all except one of the constructs (self-efficacy) were found to be significantly associated with acceptability of HPV vaccination in this study. Enhanced risk perception would increase perceived susceptibility of HPV infection. Increased perceived severity can be achieved by emphasizing the causation between HPV and both penile/anal cancers and genital warts. Such programs need to remove both financial and psychological barriers. Discounted low-cost or free HPV vaccination schemes should be provided to high risk MSM such as male sex workers and HIV-infected MSM. Psychological barriers also need to be removed, possibly by collaborating with MSM-friendly NGO and empathetic clinicians. Media campaigns tailored to accessing MSM and new approaches involving health professionals and peers should be used as cues to actions to regularly remind MSM to take up HPV vaccination. In social marketing, marketing mix includes manipulation of product, price, place and promotion to facilitate behavioral change . In our case, the key product is the HPV vaccination program. The price factors include aforementioned reduction of the cost (both psychological and financial cost) and increase in incentive of vaccination by emphasizing on its efficacy in preventing HPV, which is prevalent and results in both cancer and genital warts. The place factor refers to potential vaccination program which can be offered at NGO venues or gay-friendly clinics. The promotion factor includes promotion through social media, gay-webpage, STD clinics, gay venues and NGO venues. We can therefore use the social marketing approach, which has shown to be effective in changing many health-related behaviors  including those related to HIV , , to design HPV vaccination promotion programs. No such program has however been reported. At the policy level, long-term plans to integrate STD (including HPV infection) and HIV prevention should be considered. Our results show that about 30% of the MSM population would take up the vaccines at the current market price. The acceptability of HPV vaccination among MSM is expected to increase substantially after the implementation of some health promotion programs. Pilot implementation trials of promotion of HPV vaccination are greatly warranted.
Revision for resubmission: JL ZW JK. Conceived and designed the experiments: JL. Performed the experiments: ML. Analyzed the data: ZW CL. Wrote the paper: JL CL ZW PM JK.
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