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Open Access

Peer-reviewed

Research Article

Characterization of Transglutaminase 2 activity inhibitors in monocytes in vitro and their effect in a mouse model for multiple sclerosis

  • Navina L. Chrobok,

    Roles Conceptualization, Formal analysis, Investigation, Project administration, Visualization, Writing – original draft

    Affiliation Department of Anatomy and Neurosciences, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, The Netherlands

    ORCID logo http://orcid.org/0000-0002-2309-6709

    ⨯
  • John G. J. M. Bol,

    Roles Investigation, Methodology

    Affiliation Department of Anatomy and Neurosciences, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, The Netherlands

    ⨯
  • Cornelis A. Jongenelen,

    Roles Investigation

    Affiliation Department of Anatomy and Neurosciences, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, The Netherlands

    ⨯
  • John J. P. Brevé,

    Roles Investigation

    Affiliation Department of Anatomy and Neurosciences, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, The Netherlands

    ⨯
  • Said El Alaoui,

    Roles Resources, Supervision, Writing – review & editing

    Affiliation Covalab, Villeurbanne, France

    ⨯
  • Micha M. M. Wilhelmus,

    Roles Conceptualization, Writing – review & editing

    Affiliation Department of Anatomy and Neurosciences, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, The Netherlands

    ⨯
  • Benjamin Drukarch,

    Roles Conceptualization, Writing – review & editing

    Affiliation Department of Anatomy and Neurosciences, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, The Netherlands

    ⨯
  • Anne-Marie van Dam

    Roles Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Writing – review & editing

    * E-mail: amw.vandam@vumc.nl

    Affiliation Department of Anatomy and Neurosciences, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, The Netherlands

    ⨯

Characterization of Transglutaminase 2 activity inhibitors in monocytes in vitro and their effect in a mouse model for multiple sclerosis

  • Navina L. Chrobok, 
  • John G. J. M. Bol, 
  • Cornelis A. Jongenelen, 
  • John J. P. Brevé, 
  • Said El Alaoui, 
  • Micha M. M. Wilhelmus, 
  • Benjamin Drukarch, 
  • Anne-Marie van Dam
PLOS
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  • Published: April 24, 2018
  • https://doi.org/10.1371/journal.pone.0196433
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