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Open Access
Peer-reviewed
Research Article
Preclinical development of a vaccine against oligomeric alpha-synuclein based on virus-like particles
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Marika Doucet ,
Contributed equally to this work with: Marika Doucet, Aadil El-Turabi
Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing
¶‡ MD and AET are joint first authors. RWM and MFB are joint senior authors.
Affiliation Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford, United Kingdom
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Aadil El-Turabi ,
Contributed equally to this work with: Marika Doucet, Aadil El-Turabi
Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing
¶‡ MD and AET are joint first authors. RWM and MFB are joint senior authors.
Affiliation The Jenner Institute, Nuffield Department of Medicine, The Henry Wellcome Building for Molecular Physiology, University of Oxford, Roosevelt Drive, Oxford, United Kingdom
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Franziska Zabel,
Roles Investigation, Resources, Visualization
Affiliation Immunology, University Hospital Zürich, Zürich, Switzerland
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Benjamin H.M. Hunn,
Roles Formal analysis, Investigation, Visualization, Writing – original draft, Writing – review & editing
Affiliation Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford, United Kingdom
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Nora Bengoa-Vergniory,
Roles Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing
Affiliation Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford, United Kingdom
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Milena Cioroch,
Roles Investigation, Resources
Affiliation Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford, United Kingdom
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Mauricio Ramm,
Roles Investigation
Affiliation Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford, United Kingdom
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Amy M. Smith,
Roles Investigation
Affiliation Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford, United Kingdom
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Ariane Cruz Gomes,
Roles Resources
Affiliation The Jenner Institute, Nuffield Department of Medicine, The Henry Wellcome Building for Molecular Physiology, University of Oxford, Roosevelt Drive, Oxford, United Kingdom
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Gustavo Cabral de Miranda,
Roles Resources
Affiliation The Jenner Institute, Nuffield Department of Medicine, The Henry Wellcome Building for Molecular Physiology, University of Oxford, Roosevelt Drive, Oxford, United Kingdom
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Richard Wade-Martins ,
Roles Conceptualization, Funding acquisition, Project administration, Supervision, Validation, Writing – review & editing
* E-mail: richard.wade-martins@dpag.ox.ac.uk (RWM); martin.bachmann@ndm.ox.ac.uk (MFB)
¶‡ MD and AET are joint first authors. RWM and MFB are joint senior authors.
Affiliation Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford, United Kingdom
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Martin F. Bachmann
Roles Conceptualization, Project administration, Resources, Supervision, Validation, Writing – review & editing
* E-mail: richard.wade-martins@dpag.ox.ac.uk (RWM); martin.bachmann@ndm.ox.ac.uk (MFB)
¶‡ MD and AET are joint first authors. RWM and MFB are joint senior authors.
Affiliations The Jenner Institute, Nuffield Department of Medicine, The Henry Wellcome Building for Molecular Physiology, University of Oxford, Roosevelt Drive, Oxford, United Kingdom, Immunology, Rheumatology, Immunology and Allergy (RIA), Inselspital, University of Bern, Switzerland
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Preclinical development of a vaccine against oligomeric alpha-synuclein based on virus-like particles
- Marika Doucet,
- Aadil El-Turabi,
- Franziska Zabel,
- Benjamin H.M. Hunn,
- Nora Bengoa-Vergniory,
- Milena Cioroch,
- Mauricio Ramm,
- Amy M. Smith,
- Ariane Cruz Gomes,
- Gustavo Cabral de Miranda
- Published: August 10, 2017
- https://doi.org/10.1371/journal.pone.0181844