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Open Access
Peer-reviewed
Research Article
A phase I study of single-agent perifosine for recurrent or refractory pediatric CNS and solid tumors
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Oren J. Becher ,
Contributed equally to this work with: Oren J. Becher, Nathan E. Millard
Affiliations Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America, Department of Pediatrics, Northwestern University, Chicago, Illinois, United States of America
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Nathan E. Millard ,
Contributed equally to this work with: Oren J. Becher, Nathan E. Millard
Affiliation Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
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Shakeel Modak,
Affiliation Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
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Brian H. Kushner,
Affiliation Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
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Sofia Haque,
Affiliations Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America, Department of Radiology, Weill Cornell Medical College, New York, New York, United States of America
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Ivan Spasojevic,
Affiliation Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America
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Tanya M. Trippett,
Affiliation Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
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Stephen W. Gilheeney,
Affiliation Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
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Yasmin Khakoo,
Affiliations Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America, Departments of Pediatrics, Weill Cornell Medical College, New York, New York, United States of America
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David C. Lyden,
Affiliations Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America, Departments of Pediatrics, Weill Cornell Medical College, New York, New York, United States of America
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Kevin C. De Braganca,
Affiliation Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
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Jill M. Kolesar,
Affiliation School of Pharmacy, University of Wisconsin, Madison, Wisconsin, United States of America
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Jason T. Huse,
Affiliation Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
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Kim Kramer,
Affiliation Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
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Nai-Kong V. Cheung,
Affiliation Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
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Ira J. Dunkel
* E-mail: dunkeli@mskcc.org
Affiliations Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America, Departments of Pediatrics, Weill Cornell Medical College, New York, New York, United States of America
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A phase I study of single-agent perifosine for recurrent or refractory pediatric CNS and solid tumors
- Oren J. Becher,
- Nathan E. Millard,
- Shakeel Modak,
- Brian H. Kushner,
- Sofia Haque,
- Ivan Spasojevic,
- Tanya M. Trippett,
- Stephen W. Gilheeney,
- Yasmin Khakoo,
- David C. Lyden
- Published: June 5, 2017
- https://doi.org/10.1371/journal.pone.0178593