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Open Access

Peer-reviewed

Research Article

Melatonin protects rats from radiotherapy-induced small intestine toxicity

  • Beatriz Fernández-Gil,

    Affiliation Instituto de Biotecnología, Centro de Investigación Biomédica, Universidad de Granada, Granada, Spain

    ⨯
  • Ahmed E. Abdel Moneim,

    Affiliation Department of Zoology and Entomology, Faculty of Science, Helwan University, Cairo, Egypt

    ⨯
  • Francisco Ortiz,

    Affiliation Instituto de Biotecnología, Centro de Investigación Biomédica, Universidad de Granada, Granada, Spain

    ⨯
  • Ying-Qiang Shen,

    Affiliation Instituto de Biotecnología, Centro de Investigación Biomédica, Universidad de Granada, Granada, Spain

    ⨯
  • Viviana Soto-Mercado,

    Affiliation Neuroscience Research Group, Medical Research Institute, Faculty of Medicine, University of Antioquia, Medellin, Colombia

    ⨯
  • Miguel Mendivil-Perez,

    Affiliation Neuroscience Research Group, Medical Research Institute, Faculty of Medicine, University of Antioquia, Medellin, Colombia

    ⨯
  • Ana Guerra-Librero,

    Affiliation Instituto de Biotecnología, Centro de Investigación Biomédica, Universidad de Granada, Granada, Spain

    ⨯
  • Darío Acuña-Castroviejo,

    Affiliations Instituto de Biotecnología, Centro de Investigación Biomédica, Universidad de Granada, Granada, Spain, Departamento de Fisiología, Facultad de Medicina, Universidad de Granada, Granada, Spain

    ⨯
  • María M. Molina-Navarro,

    Affiliation Instituto Cavanilles, Universidad de Valencia, Valencia, Spain

    ⨯
  • José M. García-Verdugo,

    Affiliation Instituto Cavanilles, Universidad de Valencia, Valencia, Spain

    ⨯
  • Ramy K. A. Sayed,

    Affiliation Department of Anatomy and Embryology, Faculty of Veterinary Medicine, Sohag University, Sohag, Egypt

    ⨯
  • Javier Florido,

    Affiliation Instituto de Biotecnología, Centro de Investigación Biomédica, Universidad de Granada, Granada, Spain

    ⨯
  • Juan D. Luna,

    Affiliation Departamento de Bioestadística, Facultad de Medicina, Universidad de Granada, Granada, Spain

    ⨯
  • Luis Carlos López,

    Affiliations Instituto de Biotecnología, Centro de Investigación Biomédica, Universidad de Granada, Granada, Spain, Departamento de Fisiología, Facultad de Medicina, Universidad de Granada, Granada, Spain

    ⨯
  • Germaine Escames

    * E-mail: gescames@ugr.es

    Current address: Centro de Investigación Biomédica, Parque Tecnológico de Ciencias de la Salud, Avenida del Conocimiento s/n, Armilla, Granada, Spain

    Affiliations Instituto de Biotecnología, Centro de Investigación Biomédica, Universidad de Granada, Granada, Spain, Departamento de Fisiología, Facultad de Medicina, Universidad de Granada, Granada, Spain

    ⨯

Melatonin protects rats from radiotherapy-induced small intestine toxicity

  • Beatriz Fernández-Gil, 
  • Ahmed E. Abdel Moneim, 
  • Francisco Ortiz, 
  • Ying-Qiang Shen, 
  • Viviana Soto-Mercado, 
  • Miguel Mendivil-Perez, 
  • Ana Guerra-Librero, 
  • Darío Acuña-Castroviejo, 
  • María M. Molina-Navarro, 
  • José M. García-Verdugo
PLOS
x
  • Published: April 12, 2017
  • https://doi.org/10.1371/journal.pone.0174474
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Subject Areas
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For more information about PLOS Subject Areas, click here.

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  • Melatonin  

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  • Small intestine  

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  • Mitochondria  

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  • Cancer treatment  

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  • Gastrointestinal tract  

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  • Radiation therapy  

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  • Toxicity  

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  • Tongue  

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