Altered gut microbiome in a mouse model of Gulf War Illness causes neuroinflammation and intestinal injury via leaky gut and TLR4 activation

• Firas Alhasson ,

  Contributed equally to this work with: Firas Alhasson, Suvarthi Das, Ratanesh Seth

  Affiliation Environmental Health and Disease Laboratory, Department of Environmental Health Sciences, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina, United States of America

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• Suvarthi Das ,

  Contributed equally to this work with: Firas Alhasson, Suvarthi Das, Ratanesh Seth

  Current address: Department of Medicine (Gastroenterology), University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

  Affiliation Environmental Health and Disease Laboratory, Department of Environmental Health Sciences, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina, United States of America

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• Ratanesh Seth ,

  Contributed equally to this work with: Firas Alhasson, Suvarthi Das, Ratanesh Seth

  Affiliation Environmental Health and Disease Laboratory, Department of Environmental Health Sciences, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina, United States of America

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• Diptadip Dattaroy,

  Affiliation Environmental Health and Disease Laboratory, Department of Environmental Health Sciences, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina, United States of America

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• Varun Chandrashekaran,

  Affiliation Environmental Health and Disease Laboratory, Department of Environmental Health Sciences, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina, United States of America

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• Caitlin N. Ryan,

  Affiliation Second Genome Inc., San Francisco, California, United States of America

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• Luisa S. Chan,

  Affiliation Second Genome Inc., San Francisco, California, United States of America

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• Traci Testerman,

  Affiliation Department of Pathology, Microbiology and Immunology, University of South Carolina School of Medicine, Columbia, South Carolina, United States of America

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• James Burch,

  Affiliation Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina, United States of America

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• Lorne J. Hofseth,

  Affiliation Department of Drug Discovery and Biomedical Sciences, South Carolina College of Pharmacy, University of South Carolina, Columbia, South Carolina, United States of America

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• Ronnie Horner,

  Affiliation Department of Health Services, Policy and Management, Arnold School of Public Health, University of South Carolina. Columbia, South Carolina, United States of America

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• Mitzi Nagarkatti,

  Affiliation Department of Pathology, Microbiology and Immunology, University of South Carolina School of Medicine, Columbia, South Carolina, United States of America

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• Prakash Nagarkatti,

  Affiliation Department of Pathology, Microbiology and Immunology, University of South Carolina School of Medicine, Columbia, South Carolina, United States of America

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• Stephen M. Lasley,

  Affiliation Department of Cancer Biology and Pharmacology, University of Illinois College of Medicine, Peoria, Illinois, United States of America

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• Saurabh Chatterjee

  * E-mail: schatt@mailbox.sc.edu

  Affiliation Environmental Health and Disease Laboratory, Department of Environmental Health Sciences, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina, United States of America

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