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Open Access

Peer-reviewed

Research Article

Ethanol and High Cholesterol Diet Causes Severe Steatohepatitis and Early Liver Fibrosis in Mice

  • Yasodha Krishnasamy,

    Affiliation Department of Drug Discovery & Biomedical Sciences, Medical University of South Carolina, Charleston, South Carolina, United States of America

    ⨯
  • Venkat K. Ramshesh,

    Affiliation Department of Drug Discovery & Biomedical Sciences, Medical University of South Carolina, Charleston, South Carolina, United States of America

    ⨯
  • Monika Gooz,

    Affiliation Department of Drug Discovery & Biomedical Sciences, Medical University of South Carolina, Charleston, South Carolina, United States of America

    ⨯
  • Rick G. Schnellmann,

    Affiliations Department of Drug Discovery & Biomedical Sciences, Medical University of South Carolina, Charleston, South Carolina, United States of America, Ralph H. Johnson Veterans Affairs Medical Center, Charleston, South Carolina, United States of America

    ⨯
  • John J. Lemasters,

    Affiliations Department of Drug Discovery & Biomedical Sciences, Medical University of South Carolina, Charleston, South Carolina, United States of America, Department of Biochemistry & Molecular Biology, Medical University of South Carolina, Charleston, South Carolina, United States of America, Institute of Theoretical & Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, Russian Federation

    ⨯
  • Zhi Zhong

    * E-mail: Zhong@musc.edu

    Affiliation Department of Drug Discovery & Biomedical Sciences, Medical University of South Carolina, Charleston, South Carolina, United States of America

    ⨯

Ethanol and High Cholesterol Diet Causes Severe Steatohepatitis and Early Liver Fibrosis in Mice

  • Yasodha Krishnasamy, 
  • Venkat K. Ramshesh, 
  • Monika Gooz, 
  • Rick G. Schnellmann, 
  • John J. Lemasters, 
  • Zhi Zhong
PLOS
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  • Published: September 27, 2016
  • https://doi.org/10.1371/journal.pone.0163342
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Subject Areas
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  • Ethanol  

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  • Cholesterol  

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  • Diet  

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  • Liver fibrosis  

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  • Fibrosis  

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  • Immunoblotting  

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  • Hypercholesterolemia  

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  • Fatty liver  

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