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Open Access

Peer-reviewed

Research Article

Full Spectrum of LPS Activation in Alveolar Macrophages of Healthy Volunteers by Whole Transcriptomic Profiling

  • Miguel Pinilla-Vera ,

    Contributed equally to this work with: Miguel Pinilla-Vera, Zeyu Xiong

    Affiliation Department of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

    ⨯
  • Zeyu Xiong ,

    Contributed equally to this work with: Miguel Pinilla-Vera, Zeyu Xiong

    Affiliation Department of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

    ⨯
  • Yutong Zhao,

    Affiliations Department of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

    ⨯
  • Jing Zhao,

    Affiliations Department of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

    ⨯
  • Michael P. Donahoe,

    Affiliation Department of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

    ⨯
  • Suchitra Barge,

    Affiliation Department of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

    ⨯
  • William T. Horne,

    Affiliation Department of Pediatrics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

    ⨯
  • Jay K. Kolls,

    Affiliation Department of Pediatrics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

    ⨯
  • Bryan J. McVerry,

    Affiliation Department of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

    ⨯
  • Anastasiya Birukova,

    Affiliation Department of Medicine, Duke University, Durham, North Carolina, United States of America

    ⨯
  • Robert M. Tighe,

    Affiliation Department of Medicine, Duke University, Durham, North Carolina, United States of America

    ⨯
  • W. Michael Foster,

    Affiliation Department of Medicine, Duke University, Durham, North Carolina, United States of America

    ⨯
  • John Hollingsworth,

    Affiliations Department of Medicine, Duke University, Durham, North Carolina, United States of America, Department of Medicine, Division of Pulmonary and Critical Care Medicine, Ohio State University, Columbus, Ohio, United States of America

    ⨯
  • Anuradha Ray,

    Affiliation Department of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

    ⨯
  • Rama Mallampalli,

    Affiliation The Medical Specialty Service Line, Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, Pennsylvania, United States of America

    ⨯
  • Prabir Ray,

    Affiliation Department of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

    ⨯
  •  [ ... ],
  • Janet S. Lee

    * E-mail: leejs3@upmc.edu

    Affiliations Department of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

    ⨯
  • [ view all ]
  • [ view less ]

Full Spectrum of LPS Activation in Alveolar Macrophages of Healthy Volunteers by Whole Transcriptomic Profiling

  • Miguel Pinilla-Vera, 
  • Zeyu Xiong, 
  • Yutong Zhao, 
  • Jing Zhao, 
  • Michael P. Donahoe, 
  • Suchitra Barge, 
  • William T. Horne, 
  • Jay K. Kolls, 
  • Bryan J. McVerry, 
  • Anastasiya Birukova
PLOS
x
  • Published: July 19, 2016
  • https://doi.org/10.1371/journal.pone.0159329
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  • Alveolar macrophages  

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  • Interferons  

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  • Small interfering RNA  

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  • Macrophages  

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  • Gene ontologies  

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