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Open Access

Peer-reviewed

Research Article

Preferential Secretion of Thymic Stromal Lymphopoietin (TSLP) by Terminally Differentiated Esophageal Epithelial Cells: Relevance to Eosinophilic Esophagitis (EoE)

  • Prasanna M. Chandramouleeswaran,

    Affiliation Division of Gastroenterology, Hepatology, and Nutrition, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, United States of America

    ⨯
  • Dawen Shen,

    Affiliation Division of Gastroenterology, Hepatology, and Nutrition, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, United States of America

    ⨯
  • Anna J. Lee,

    Affiliation Division of Gastroenterology, Hepatology, and Nutrition, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, United States of America

    ⨯
  • Alain Benitez,

    Affiliation Division of Gastroenterology, Hepatology, and Nutrition, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, United States of America

    ⨯
  • Kara Dods,

    Affiliation Division of Gastroenterology, Hepatology, and Nutrition, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, United States of America

    ⨯
  • Fiona Gambanga,

    Affiliation Division of Gastroenterology, Hepatology, and Nutrition, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, United States of America

    ⨯
  • Benjamin J. Wilkins,

    Affiliation Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States of America

    ⨯
  • Jamie Merves,

    Affiliations Division of Gastroenterology, Hepatology, and Nutrition, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, United States of America, Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States of America

    ⨯
  • Yuliana Noah,

    Affiliation Division of Gastroenterology, Hepatology, and Nutrition, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, United States of America

    ⨯
  • Sarit Toltzis,

    Affiliation Division of Gastroenterology, Hepatology, and Nutrition, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, United States of America

    ⨯
  • Jennifer H. Yearley,

    Affiliation Department of Immunology, Merck Research Labs, Palo Alto, California 94304, United States of America

    ⨯
  • Jonathan M. Spergel,

    Affiliations Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States of America, Division of Allergy and Immunology, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, United States of America

    ⨯
  • Hiroshi Nakagawa,

    Affiliation Division of Gastroenterology, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States of America

    ⨯
  • Rene deWaal Malefyt,

    Affiliation Department of Immunology, Merck Research Labs, Palo Alto, California 94304, United States of America

    ⨯
  • Amanda B. Muir ,

    * E-mail: wangm@email.chop.edu (MLW); muira@email.chop.edu (ABM)

    Affiliations Division of Gastroenterology, Hepatology, and Nutrition, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, United States of America, Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States of America

    ⨯
  •  [ ... ],
  • Mei-Lun Wang

    * E-mail: wangm@email.chop.edu (MLW); muira@email.chop.edu (ABM)

    Affiliations Division of Gastroenterology, Hepatology, and Nutrition, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, United States of America, Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States of America

    ⨯
  • [ view all ]
  • [ view less ]

Preferential Secretion of Thymic Stromal Lymphopoietin (TSLP) by Terminally Differentiated Esophageal Epithelial Cells: Relevance to Eosinophilic Esophagitis (EoE)

  • Prasanna M. Chandramouleeswaran, 
  • Dawen Shen, 
  • Anna J. Lee, 
  • Alain Benitez, 
  • Kara Dods, 
  • Fiona Gambanga, 
  • Benjamin J. Wilkins, 
  • Jamie Merves, 
  • Yuliana Noah, 
  • Sarit Toltzis
PLOS
x
  • Published: March 18, 2016
  • https://doi.org/10.1371/journal.pone.0150968
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  • Cell differentiation  

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  • Epithelial cells  

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  • Food  

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  • Immune response  

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  • Secretion  

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