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Open Access

Peer-reviewed

Research Article

Influenza Vaccine Manufacturing: Effect of Inactivation, Splitting and Site of Manufacturing. Comparison of Influenza Vaccine Production Processes

  • Theone C. Kon ,

    * E-mail: theone.kon@intravacc.nl

    Affiliation Department of Product Development, Intravacc, Institute for Translational Vaccinology, Bilthoven, The Netherlands

    ⨯
  • Adrian Onu,

    Affiliation Laboratory of Biotechnology, Cantacuzino National Research Institute, Bucharest, Romania

    ⨯
  • Laurentiu Berbecila,

    Affiliation Unit of Influenza Vaccine Production, Cantacuzino National Research Institute, Bucharest, Romania

    ⨯
  • Emilia Lupulescu,

    Affiliation Laboratory of Respiratory Viral Infections, Cantacuzino National Research Institute, Bucharest, Romania

    ⨯
  • Alina Ghiorgisor,

    Affiliation Laboratory of Respiratory Viral Infections, Cantacuzino National Research Institute, Bucharest, Romania

    ⨯
  • Gideon F. Kersten,

    Affiliation Department of Research, Intravacc, Institute for Translational Vaccinology, Bilthoven, The Netherlands

    ⨯
  • Yi-Qing Cui,

    Affiliation Department of Product Development, Intravacc, Institute for Translational Vaccinology, Bilthoven, The Netherlands

    ⨯
  • Jean-Pierre Amorij ,

    ¶‡ These authors are shared last authors on this work.

    Affiliation Department of Business Development, Intravacc, Institute for Translational Vaccinology, Bilthoven, The Netherlands

    ⨯
  • Leo Van der Pol

    ¶‡ These authors are shared last authors on this work.

    Affiliation Department of Research, Intravacc, Institute for Translational Vaccinology, Bilthoven, The Netherlands

    ⨯

Influenza Vaccine Manufacturing: Effect of Inactivation, Splitting and Site of Manufacturing. Comparison of Influenza Vaccine Production Processes

  • Theone C. Kon, 
  • Adrian Onu, 
  • Laurentiu Berbecila, 
  • Emilia Lupulescu, 
  • Alina Ghiorgisor, 
  • Gideon F. Kersten, 
  • Yi-Qing Cui, 
  • Jean-Pierre Amorij, 
  • Leo Van der Pol
PLOS
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  • Published: March 9, 2016
  • https://doi.org/10.1371/journal.pone.0150700
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