Adding Vitamin E-TPGS to the Formulation of Genexol-PM: Specially Mixed Micelles Improve Drug-Loading Ability and Cytotoxicity against Multidrug-Resistant Tumors Significantly

Zhuoyang Fan; Cheng Chen; Xiaoying Pang; Zhou Yu; Yang Qi; Xinyi Chen; Huihui Liang; Xiaoling Fang; Xianyi Sha

doi:10.1371/journal.pone.0120129

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Peer-reviewed

Research Article

Adding Vitamin E-TPGS to the Formulation of Genexol-PM: Specially Mixed Micelles Improve Drug-Loading Ability and Cytotoxicity against Multidrug-Resistant Tumors Significantly

Zhuoyang Fan,

Affiliation Key Laboratory of Smart Drug Delivery (Fudan University), Ministry of Education & PLA, Department of Pharmaceutics, School of Pharmacy, Fudan University, Lane 826, Zhangheng Road, Shanghai 201203, China
⨯
Cheng Chen,

Affiliation Key Laboratory of Smart Drug Delivery (Fudan University), Ministry of Education & PLA, Department of Pharmaceutics, School of Pharmacy, Fudan University, Lane 826, Zhangheng Road, Shanghai 201203, China
⨯
Xiaoying Pang,

Affiliation Key Laboratory of Smart Drug Delivery (Fudan University), Ministry of Education & PLA, Department of Pharmaceutics, School of Pharmacy, Fudan University, Lane 826, Zhangheng Road, Shanghai 201203, China
⨯
Zhou Yu,

Affiliation Key Laboratory of Smart Drug Delivery (Fudan University), Ministry of Education & PLA, Department of Pharmaceutics, School of Pharmacy, Fudan University, Lane 826, Zhangheng Road, Shanghai 201203, China
⨯
Yang Qi,

Affiliation Key Laboratory of Smart Drug Delivery (Fudan University), Ministry of Education & PLA, Department of Pharmaceutics, School of Pharmacy, Fudan University, Lane 826, Zhangheng Road, Shanghai 201203, China
⨯
Xinyi Chen,

Affiliation Key Laboratory of Smart Drug Delivery (Fudan University), Ministry of Education & PLA, Department of Pharmaceutics, School of Pharmacy, Fudan University, Lane 826, Zhangheng Road, Shanghai 201203, China
⨯
Huihui Liang,

Affiliation Key Laboratory of Smart Drug Delivery (Fudan University), Ministry of Education & PLA, Department of Pharmaceutics, School of Pharmacy, Fudan University, Lane 826, Zhangheng Road, Shanghai 201203, China
⨯
Xiaoling Fang,

Affiliation Key Laboratory of Smart Drug Delivery (Fudan University), Ministry of Education & PLA, Department of Pharmaceutics, School of Pharmacy, Fudan University, Lane 826, Zhangheng Road, Shanghai 201203, China
⨯
Xianyi Sha

* E-mail: shaxy@fudan.edu.cn

Affiliation Key Laboratory of Smart Drug Delivery (Fudan University), Ministry of Education & PLA, Department of Pharmaceutics, School of Pharmacy, Fudan University, Lane 826, Zhangheng Road, Shanghai 201203, China
⨯

Adding Vitamin E-TPGS to the Formulation of Genexol-PM: Specially Mixed Micelles Improve Drug-Loading Ability and Cytotoxicity against Multidrug-Resistant Tumors Significantly

Zhuoyang Fan,
Cheng Chen,
Xiaoying Pang,
Zhou Yu,
Yang Qi,
Xinyi Chen,
Huihui Liang,
Xiaoling Fang,
Xianyi Sha

Published: April 1, 2015
https://doi.org/10.1371/journal.pone.0120129

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Polymers
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Cancers and neoplasms
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Vitamins
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Lung and intrathoracic tumors
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Cancer treatment
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