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Open Access
Peer-reviewed
Research Article
Ex Vivo Cytosolic Delivery of Functional Macromolecules to Immune Cells
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Armon Sharei ,
Contributed equally to this work with: Armon Sharei, Radiana Trifonova, Siddharth Jhunjhunwala
Affiliations Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, The Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America, The Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
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Radiana Trifonova ,
Contributed equally to this work with: Armon Sharei, Radiana Trifonova, Siddharth Jhunjhunwala
Affiliation Program in Cellular and Molecular Medicine, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
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Siddharth Jhunjhunwala ,
Contributed equally to this work with: Armon Sharei, Radiana Trifonova, Siddharth Jhunjhunwala
Affiliation The Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
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George C. Hartoularos,
Affiliation Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
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Alexandra T. Eyerman,
Affiliation Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
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Abigail Lytton-Jean,
Affiliation The Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
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Mathieu Angin,
Affiliation The Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America
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Siddhartha Sharma,
Affiliation The Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America
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Roberta Poceviciute,
Affiliation Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
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Shirley Mao,
Affiliation Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
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Megan Heimann,
Affiliation Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
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Sophia Liu,
Affiliation Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
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Tanya Talkar,
Affiliation Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
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Omar F. Khan,
Affiliation The Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
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Marylyn Addo,
Affiliation The Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America
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Ulrich H. von Andrian,
Affiliations The Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America
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Daniel G. Anderson,
Affiliations Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, The Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
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Robert Langer,
Affiliations Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, The Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
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Judy Lieberman ,
* E-mail: judy.lieberman@childrens.harvard.edu (JL); kfjensen@mit.edu (KFJ)
Affiliation Program in Cellular and Molecular Medicine, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
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Klavs F. Jensen
* E-mail: judy.lieberman@childrens.harvard.edu (JL); kfjensen@mit.edu (KFJ)
Affiliation Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
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Ex Vivo Cytosolic Delivery of Functional Macromolecules to Immune Cells
- Armon Sharei,
- Radiana Trifonova,
- Siddharth Jhunjhunwala,
- George C. Hartoularos,
- Alexandra T. Eyerman,
- Abigail Lytton-Jean,
- Mathieu Angin,
- Siddhartha Sharma,
- Roberta Poceviciute,
- Shirley Mao
- Published: April 13, 2015
- https://doi.org/10.1371/journal.pone.0118803