Synthesis and Mechanistic Studies of a Novel Homoisoflavanone Inhibitor of Endothelial Cell Growth

• Halesha D. Basavarajappa ,

  Contributed equally to this work with: Halesha D. Basavarajappa, Bit Lee

  Affiliations Eugene and Marilyn Glick Eye Institute, Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America, Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

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• Bit Lee ,

  Contributed equally to this work with: Halesha D. Basavarajappa, Bit Lee

  Affiliation College of Pharmacy, Gachon University, Incheon, South Korea

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• Xiang Fei,

  Affiliation College of Pharmacy, Gachon University, Incheon, South Korea

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• Daesung Lim,

  Affiliation College of Pharmacy, Gachon University, Incheon, South Korea

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• Breedge Callaghan,

  Affiliation Eugene and Marilyn Glick Eye Institute, Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

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• Julie A. Mund,

  Affiliations Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America, Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, Indiana, United States Of America

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• Jamie Case,

  Affiliations Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America, Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, Indiana, United States Of America

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• Gangaraju Rajashekhar,

  Affiliations Eugene and Marilyn Glick Eye Institute, Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America, Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

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• Seung-Yong Seo ,

  * E-mail: syseo@gachon.ac.kr (S-YS); tcorson@iupui.edu (TWC)

  ¶These authors also contributed equally to this work.

  Affiliation College of Pharmacy, Gachon University, Incheon, South Korea

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• Timothy W. Corson

  * E-mail: syseo@gachon.ac.kr (S-YS); tcorson@iupui.edu (TWC)

  ¶These authors also contributed equally to this work.

  Affiliations Eugene and Marilyn Glick Eye Institute, Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America, Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America, Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, Indiana, United States Of America, Department of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

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