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Open Access
Peer-reviewed
Research Article
Analysis of Rare Variants in the C3 Gene in Patients with Age-Related Macular Degeneration
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Maheswara R. Duvvari,
Affiliations Department of Ophthalmology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands
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Codrut C. Paun,
Affiliations Department of Ophthalmology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands
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Gabriëlle H. S. Buitendijk,
Affiliations Department of Ophthalmology, Erasmus Medical Centre, Rotterdam, the Netherlands, Department of Epidemiology, Erasmus Medical Centre, Rotterdam, the Netherlands
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Nicole T. M. Saksens,
Affiliation Department of Ophthalmology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands
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Elena B. Volokhina,
Affiliation Department of Pediatric Nephrology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands
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Tina Ristau,
Affiliation Department of Vitreoretinal Surgery, Department of Ophthalmology, University Hospital of Cologne, Cologne, Germany
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Frederieke E. Schoenmaker-Koller,
Affiliation Department of Ophthalmology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands
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Johannes P. H. van de Ven,
Affiliation Department of Ophthalmology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands
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Joannes M. M. Groenewoud,
Affiliation Department for Health and Evidence, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands
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Lambertus P. W. J. van den Heuvel,
Affiliation Department of Pediatric Nephrology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands
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Albert Hofman,
Affiliations Department of Epidemiology, Erasmus Medical Centre, Rotterdam, the Netherlands, Netherlands Consortium for Healthy Aging, Netherlands Genomics Initiative, the Hague, the Netherlands
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Sascha Fauser,
Affiliation Department of Vitreoretinal Surgery, Department of Ophthalmology, University Hospital of Cologne, Cologne, Germany
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André G. Uitterlinden,
Affiliations Department of Epidemiology, Erasmus Medical Centre, Rotterdam, the Netherlands, Netherlands Consortium for Healthy Aging, Netherlands Genomics Initiative, the Hague, the Netherlands, Department of Internal Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands
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Caroline C. W. Klaver,
Affiliations Department of Ophthalmology, Erasmus Medical Centre, Rotterdam, the Netherlands, Department of Epidemiology, Erasmus Medical Centre, Rotterdam, the Netherlands
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Carel B. Hoyng,
Affiliation Department of Ophthalmology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands
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Eiko K. de Jong,
Affiliations Department of Ophthalmology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands
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Anneke I. den Hollander
* E-mail: Anneke.denHollander@radboudumc.nl
Affiliations Department of Ophthalmology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands, Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands
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Analysis of Rare Variants in the C3 Gene in Patients with Age-Related Macular Degeneration
- Maheswara R. Duvvari,
- Codrut C. Paun,
- Gabriëlle H. S. Buitendijk,
- Nicole T. M. Saksens,
- Elena B. Volokhina,
- Tina Ristau,
- Frederieke E. Schoenmaker-Koller,
- Johannes P. H. van de Ven,
- Joannes M. M. Groenewoud,
- Lambertus P. W. J. van den Heuvel
- Published: April 15, 2014
- https://doi.org/10.1371/journal.pone.0094165