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Open Access

Peer-reviewed

Research Article

Quercetin Is More Effective than Cromolyn in Blocking Human Mast Cell Cytokine Release and Inhibits Contact Dermatitis and Photosensitivity in Humans

  • Zuyi Weng ,

    Contributed equally to this work with: Zuyi Weng, Bodi Zhang

    Affiliations Molecular Immunopharmacology and Drug Discovery Laboratory, Department of Molecular Physiology and Pharmacology, Tufts University School of Medicine, Boston, Massachusetts, United States of America, Sackler School of Graduate Biomedical Sciences, Tufts University, Boston, Massachusetts, United States of America

    ⨯
  • Bodi Zhang ,

    Contributed equally to this work with: Zuyi Weng, Bodi Zhang

    Affiliations Molecular Immunopharmacology and Drug Discovery Laboratory, Department of Molecular Physiology and Pharmacology, Tufts University School of Medicine, Boston, Massachusetts, United States of America, Sackler School of Graduate Biomedical Sciences, Tufts University, Boston, Massachusetts, United States of America, Department of Biochemistry, Tufts University School of Medicine, Boston, Massachusetts, United States of America

    ⨯
  • Shahrzad Asadi,

    Affiliations Molecular Immunopharmacology and Drug Discovery Laboratory, Department of Molecular Physiology and Pharmacology, Tufts University School of Medicine, Boston, Massachusetts, United States of America, Department of Pharmacy, Tufts Medical Center, Boston, Massachusetts, United States of America

    ⨯
  • Nikolaos Sismanopoulos,

    Affiliation Molecular Immunopharmacology and Drug Discovery Laboratory, Department of Molecular Physiology and Pharmacology, Tufts University School of Medicine, Boston, Massachusetts, United States of America

    ⨯
  • Alan Butcher,

    Affiliation Thorne Research, Inc., Sandpoint, Idaho, United States of America

    ⨯
  • Xueyan Fu,

    Affiliation Vitamin K Lab, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts, United States of America

    ⨯
  • Alexandra Katsarou-Katsari,

    Affiliation First Department of Dermatology, A. Sygros Hospital, Athens University Medical School, Athens, Greece

    ⨯
  • Christina Antoniou,

    Affiliation First Department of Dermatology, A. Sygros Hospital, Athens University Medical School, Athens, Greece

    ⨯
  • Theoharis C. Theoharides

    * E-mail: theoharis.theoharides@tufts.edu

    Affiliations Molecular Immunopharmacology and Drug Discovery Laboratory, Department of Molecular Physiology and Pharmacology, Tufts University School of Medicine, Boston, Massachusetts, United States of America, Sackler School of Graduate Biomedical Sciences, Tufts University, Boston, Massachusetts, United States of America, Department of Biochemistry, Tufts University School of Medicine, Boston, Massachusetts, United States of America, Department of Internal Medicine, Tufts University School of Medicine and Tufts Medical Center, Boston, Massachusetts, United States of America

    ⨯

Quercetin Is More Effective than Cromolyn in Blocking Human Mast Cell Cytokine Release and Inhibits Contact Dermatitis and Photosensitivity in Humans

  • Zuyi Weng, 
  • Bodi Zhang, 
  • Shahrzad Asadi, 
  • Nikolaos Sismanopoulos, 
  • Alan Butcher, 
  • Xueyan Fu, 
  • Alexandra Katsarou-Katsari, 
  • Christina Antoniou, 
  • Theoharis C. Theoharides
PLOS
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  • Published: March 28, 2012
  • https://doi.org/10.1371/journal.pone.0033805
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