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Open Access
Peer-reviewed
Research Article
Lipidomics Reveals Multiple Pathway Effects of a Multi-Components Preparation on Lipid Biochemistry in ApoE*3Leiden.CETP Mice
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Heng Wei ,
Contributed equally to this work with: Heng Wei, Chunxiu Hu, Mei Wang
Affiliations Department of Earth, Environmental and Life Science, TNO, Zeist, The Netherlands, Sino-Dutch Centre for Preventive and Personalized Medicine, Zeist, The Netherlands
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Chunxiu Hu ,
Contributed equally to this work with: Heng Wei, Chunxiu Hu, Mei Wang
Affiliations Division of Analytical Bioscience, Leiden/Amsterdam Center for Drug Research, Leiden University, Leiden, The Netherlands, CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China
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Mei Wang ,
Contributed equally to this work with: Heng Wei, Chunxiu Hu, Mei Wang
Affiliations Sino-Dutch Centre for Preventive and Personalized Medicine, Zeist, The Netherlands, SU BioMedicine, Zeist, The Netherlands
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Anita M. van den Hoek,
Affiliation Metabolic Health Research, TNO, Leiden, The Netherlands
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Theo H. Reijmers,
Affiliations Division of Analytical Bioscience, Leiden/Amsterdam Center for Drug Research, Leiden University, Leiden, The Netherlands, Netherlands Metabolomics Centre, Leiden University, Leiden, The Netherlands
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Suzan Wopereis,
Affiliation Department of Earth, Environmental and Life Science, TNO, Zeist, The Netherlands
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Jildau Bouwman,
Affiliations Department of Earth, Environmental and Life Science, TNO, Zeist, The Netherlands, Netherlands Metabolomics Centre, Leiden University, Leiden, The Netherlands
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Raymond Ramaker,
Affiliation Department of Earth, Environmental and Life Science, TNO, Zeist, The Netherlands
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Henrie A. A. J. Korthout,
Affiliation Fytagoras B.V, Leiden, The Netherlands
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Marco Vennik,
Affiliation Fytagoras B.V, Leiden, The Netherlands
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Thomas Hankemeier,
Affiliations Division of Analytical Bioscience, Leiden/Amsterdam Center for Drug Research, Leiden University, Leiden, The Netherlands, Netherlands Metabolomics Centre, Leiden University, Leiden, The Netherlands
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Louis M. Havekes,
Affiliations Metabolic Health Research, TNO, Leiden, The Netherlands, Department of Endocrinology and Cardiology, Leiden University Medical Centre, Leiden, The Netherlands
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Renger F. Witkamp,
Affiliation Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands
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Elwin R. Verheij,
Affiliation Department of Earth, Environmental and Life Science, TNO, Zeist, The Netherlands
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Guowang Xu ,
* E-mail: jan.vandergreef@tno.nl (JVDG); xugw@dicp.ac.cn (GX)
Affiliations Sino-Dutch Centre for Preventive and Personalized Medicine, Zeist, The Netherlands, CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China
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Jan van der Greef
* E-mail: jan.vandergreef@tno.nl (JVDG); xugw@dicp.ac.cn (GX)
Affiliations Department of Earth, Environmental and Life Science, TNO, Zeist, The Netherlands, Sino-Dutch Centre for Preventive and Personalized Medicine, Zeist, The Netherlands, Division of Analytical Bioscience, Leiden/Amsterdam Center for Drug Research, Leiden University, Leiden, The Netherlands, SU BioMedicine, Zeist, The Netherlands
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Lipidomics Reveals Multiple Pathway Effects of a Multi-Components Preparation on Lipid Biochemistry in ApoE*3Leiden.CETP Mice
- Heng Wei,
- Chunxiu Hu,
- Mei Wang,
- Anita M. van den Hoek,
- Theo H. Reijmers,
- Suzan Wopereis,
- Jildau Bouwman,
- Raymond Ramaker,
- Henrie A. A. J. Korthout,
- Marco Vennik
- Published: January 23, 2012
- https://doi.org/10.1371/journal.pone.0030332