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Open Access

Peer-reviewed

Research Article

Atopic Dermatitis-Like Disease and Associated Lethal Myeloproliferative Disorder Arise from Loss of Notch Signaling in the Murine Skin

  • Alexis Dumortier ,

    Contributed equally to this work with: Alexis Dumortier, André-Dante Durham

    Affiliation Ecole Polytechnique Fédérale de Lausanne (EPFL SV ISREC), Lausanne, Switzerland

    ⨯
  • André-Dante Durham ,

    Contributed equally to this work with: Alexis Dumortier, André-Dante Durham

    Affiliation Ecole Polytechnique Fédérale de Lausanne (EPFL SV ISREC), Lausanne, Switzerland

    ⨯
  • Matteo Di Piazza,

    Affiliation Ecole Polytechnique Fédérale de Lausanne (EPFL SV ISREC), Lausanne, Switzerland

    ⨯
  • Sophie Vauclair,

    Affiliation Ecole Polytechnique Fédérale de Lausanne (EPFL SV ISREC), Lausanne, Switzerland

    ⨯
  • Ute Koch,

    Affiliation Ecole Polytechnique Fédérale de Lausanne (EPFL SV ISREC), Lausanne, Switzerland

    ⨯
  • Gisèle Ferrand,

    Affiliation Ecole Polytechnique Fédérale de Lausanne (EPFL SV ISREC), Lausanne, Switzerland

    ⨯
  • Isabel Ferrero,

    Affiliation Ludwig Institute for Cancer Research, Lausanne Branch, University of Lausanne, Epalinges, Switzerland

    ⨯
  • Shadmehr Demehri,

    Affiliation Department of Developmental Biology and Division of Dermatology, Washington University School of Medicine, St. Louis, Missouri, United States of America

    ⨯
  • Lynda Li Song,

    Affiliation Breast Cancer Program, Cardinal Bernardin Cancer Center, Loyola University Chicago, Chicago, Illinois, United States of America

    ⨯
  • Andrew G. Farr,

    Affiliation Department of Biological Structure and Department of Immunology, University of Washington, Seattle, Washington, United States of America

    ⨯
  • Warren J. Leonard,

    Affiliation Laboratory of Molecular Immunology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America

    ⨯
  • Raphael Kopan,

    Affiliation Department of Developmental Biology and Division of Dermatology, Washington University School of Medicine, St. Louis, Missouri, United States of America

    ⨯
  • Lucio Miele,

    Affiliation Breast Cancer Program, Cardinal Bernardin Cancer Center, Loyola University Chicago, Chicago, Illinois, United States of America

    ⨯
  • Daniel Hohl,

    Affiliation Department of Dermatology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland

    ⨯
  • Daniela Finke,

    Affiliation Center for Biomedicine, Department of Clinical and Biological Sciences (DKBW), University of Basel, Basel, Switzerland

    ⨯
  •  [ ... ],
  • Freddy Radtke

    * E-mail: Freddy.Radtke@epfl.ch

    Affiliation Ecole Polytechnique Fédérale de Lausanne (EPFL SV ISREC), Lausanne, Switzerland

    ⨯
  • [ view all ]
  • [ view less ]

Atopic Dermatitis-Like Disease and Associated Lethal Myeloproliferative Disorder Arise from Loss of Notch Signaling in the Murine Skin

  • Alexis Dumortier, 
  • André-Dante Durham, 
  • Matteo Di Piazza, 
  • Sophie Vauclair, 
  • Ute Koch, 
  • Gisèle Ferrand, 
  • Isabel Ferrero, 
  • Shadmehr Demehri, 
  • Lynda Li Song, 
  • Andrew G. Farr
PLOS
x
  • Published: February 18, 2010
  • https://doi.org/10.1371/journal.pone.0009258
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Subject Areas
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For more information about PLOS Subject Areas, click here.

We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

  • Notch signaling  

    Is the Subject Area "Notch signaling" applicable to this article?

    Thanks for your feedback.

  • B cells  

    Is the Subject Area "B cells" applicable to this article?

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  • Epidermis  

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  • Genetically modified animals  

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  • Cytokines  

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  • Spleen  

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  • Bone marrow cells  

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  • Dermis  

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