PONE-D-21-38940Indigenous vegetables of family Cucurbitaceae of Azad Kashmir: A key emphasis to their pharmacological potentialPLOS ONE

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Academic Editor

PLOS ONE

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Reviewers' comments:

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Comments to the Author

1. Is the manuscript technically sound, and do the data support the conclusions?

The manuscript must describe a technically sound piece of scientific research with data that supports the conclusions. Experiments must have been conducted rigorously, with appropriate controls, replication, and sample sizes. The conclusions must be drawn appropriately based on the data presented.

Reviewer #1: Yes

Reviewer #2: Partly

Reviewer #3: No

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2. Has the statistical analysis been performed appropriately and rigorously?

Reviewer #1: Yes

Reviewer #2: Yes

Reviewer #3: No

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Reviewer #1: Yes

Reviewer #2: Yes

Reviewer #3: Yes

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4. Is the manuscript presented in an intelligible fashion and written in standard English?

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Reviewer #1: Yes

Reviewer #2: Yes

Reviewer #3: No

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5. Review Comments to the Author

Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters)

Reviewer #1: 1.Why selected these plants from the whole family?

2. Provide the importance and recommendations of the study.

3. Cross check the reference with main body text.

4. Typographical and English language corrections need improvement.

Reviewer #2: The abstract is very concise but abbreviation used more. So, correct it. Introduction is very brief. it does not cover whole topic. Add relevant data in introduction in sequence. Methods are designed in good form. Results description showed lack of justifications. Please add suitable discussion. Conclusion is not properly indicated key findings. All References must be formatted according to given format of the journal. Some spelling mistakes are observed. So, I think, major revision of the paper is required

Reviewer #3: Indigenous vegetables of family Cucurbitaceae of Azad Kashmir: A key emphasis to their pharmacological potential

I congratulate authors for presenting a nice MS. The MS is well written. However there are some issues to be corrected before publishing.

Grammatical mistake

µgm/ mL;

Genus and species must have gap;

Mistake in ref 15 and 26

Please make reference crosschecking for similar type of work,

What is the difference between this work and previous works (Ref 24, Ref 25, Ref 26, Ref 31)?

What is the reason for positive, negative and no correlation of peel, pulp and seed. Is there any evidence from this research?

What is take home message from this study? Please state this nutshell in conclusion.

What is the global/regional inferences of this study?

All the best!

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Reviewer #1: No

Reviewer #2: No

Reviewer #3: No

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PONE-D-21-38940R1Indigenous vegetables of family Cucurbitaceae of Azad Kashmir: A key emphasis to their pharmacological potentialPLOS ONE

Dear Dr. SB,

Thank you for submitting your manuscript to PLOS ONE. After careful consideration, we feel that it has merit but does not fully meet PLOS ONE’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process.

==============================

ACADEMIC EDITOR: Please insert comments here and delete this placeholder text when finished. Be sure to:

Please correct paper as guided now for improvement, see comments section

==============================

Please submit your revised manuscript by May 26 2022 11:59PM. If you will need more time than this to complete your revisions, please reply to this message or contact the journal office at plosone@plos.org. When you're ready to submit your revision, log on to https://www.editorialmanager.com/pone/ and select the 'Submissions Needing Revision' folder to locate your manuscript file.

Please include the following items when submitting your revised manuscript:

• A rebuttal letter that responds to each point raised by the academic editor and reviewer(s). You should upload this letter as a separate file labeled 'Response to Reviewers'.
• A marked-up copy of your manuscript that highlights changes made to the original version. You should upload this as a separate file labeled 'Revised Manuscript with Track Changes'.
• An unmarked version of your revised paper without tracked changes. You should upload this as a separate file labeled 'Manuscript'.

If you would like to make changes to your financial disclosure, please include your updated statement in your cover letter. Guidelines for resubmitting your figure files are available below the reviewer comments at the end of this letter.

If applicable, we recommend that you deposit your laboratory protocols in protocols.io to enhance the reproducibility of your results. Protocols.io assigns your protocol its own identifier (DOI) so that it can be cited independently in the future. For instructions see: https://journals.plos.org/plosone/s/submission-guidelines#loc-laboratory-protocols. Additionally, PLOS ONE offers an option for publishing peer-reviewed Lab Protocol articles, which describe protocols hosted on protocols.io. Read more information on sharing protocols at https://plos.org/protocols?utm_medium=editorial-email&utm_source=authorletters&utm_campaign=protocols.

We look forward to receiving your revised manuscript.

Kind regards,

Muhammad Ishtiaq

Academic Editor

PLOS ONE

Journal Requirements:

Please review your reference list to ensure that it is complete and correct. If you have cited papers that have been retracted, please include the rationale for doing so in the manuscript text, or remove these references and replace them with relevant current references. Any changes to the reference list should be mentioned in the rebuttal letter that accompanies your revised manuscript. If you need to cite a retracted article, indicate the article’s retracted status in the References list and also include a citation and full reference for the retraction notice.

Additional Editor Comments (if provided):

The paper albeit has been updated as per reviewers' comments but it needs further improvements. Please correct as:

1) -- Table 1, see percentage yield is not correct, it should be revised

2) ---Table 2, write full name of plant in Latin

3)- -Table 3, write full name of plant in Latin

4) revise English language, get expertise from Native English speaker or from any Professor of English Deptt of your University and also add his letter

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Reviewers' comments:

[NOTE: If reviewer comments were submitted as an attachment file, they will be attached to this email and accessible via the submission site. Please log into your account, locate the manuscript record, and check for the action link "View Attachments". If this link does not appear, there are no attachment files.]

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Indigenous vegetables of family Cucurbitaceae of Azad Kashmir: A key emphasis on their pharmacological potential

PONE-D-21-38940R2

Dear Dr. Kalsoom Akhter ,

We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements.

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Kind regards,

Muhammad Ishtiaq

Academic Editor

PLOS ONE

Additional Editor Comments (optional):

The paper is well written and properly updated

Reviewers' comments: