PONE-D-20-31068

Comparison of the disinfecting effect of sodium hypochlorite aqueous solution and surfactant on hospital kitchen hygiene using adenosine triphosphate swab testing

PLOS ONE

Dear Dr. Takashi Aoyama,

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We look forward to receiving your revised manuscript.

Kind regards,

Hans-Uwe Dahms, Ph.D.

Academic Editor

PLOS ONE

Additional Editor Comments:

The work was conducted carefully and provides sufficient data. The flow of thought is convincing and the English is suitable.

Unfortunately, INTRODUCTION and DISCUSSION (of own RESULTS and those of others are not detailed at this point! It is suggested that the authors add more reflections around the many MORE disinfection methods (incl. NON-CHEMICAL), comparison with available protocols WORLDWIDE, and report more DISCUSSION about these issues. For example ATP- approach will NOT detecet VIRUSES and it should be critically evaluated whether the ATP endpoint for a bioassay is appropriate to monitor MICROBES as well as pathogenic molecules like viruses....Would fungi be equally assayed with ATP? A minimum of 25-30 REFERENCES would be necessary to provide an in depth DISCUSSION.

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Reviewers' comments:

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Reviewer #1: Partly

Reviewer #2: Yes

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2. Has the statistical analysis been performed appropriately and rigorously?

Reviewer #1: No

Reviewer #2: Yes

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Reviewer #1: Yes

Reviewer #2: No

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Reviewer #1: Yes

Reviewer #2: Yes

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5. Review Comments to the Author

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Reviewer #1: After examining the manuscript, I am of the view that it is not suitable for publication in current form. Although the work appears to have been conducted carefully, unfortunately data, experiments and discussion are not enough, hence, not suitable for publication in this journal.

It is suggested that the authors should add more experimental data of various disinfection methods, comparison with available protocols, and report more discussion.

Reviewer #2: After examining the manuscript, I am of the view that it is not suitable for publication in current form, particularly since an IN DEPTH DISCUSSION and LITERATURE update is missing. The work was conducted carefully and provides sufficient data

for its objectives. The flow of thought is convincing and the English is suitable.

Unfortunately, INTRODUCTION and DISCUSSION (of own RESULTS and those of others are not enough as yet! It is suggested that the authors add more reflections around the many MORE disinfection methods (incl. NON-CHEMICAL), comparison with available protocols WORLDWIDE, and report more DISCUSSION about these issues.

For example ATP- approach will NOT detecet VIRUSES and it should be critically evaluated whether the ATP endpoint for a bioassay is appropriate to monitor MICROBES as well as pathogenic molecules like viruses....Would fungi be equally assayed with ATP?

A minimum of 25-30 REFERENCES would be necessary to provide an in depth DISCUSSION.

Are ALL THE DATA made available to the reader? If not, pls. provide those TABLE information as

Supplementary files.

I am adding an amended version of the MS herewith.

END

Hans-Uwe Dahms

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Reviewer #1: No

Reviewer #2: No

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Attachments

Attachment

Submitted filename: PONE-D-20-31068_reviewer KITCHEN.pdf

Comparison of the disinfecting effect of sodium hypochlorite aqueous solution and surfactant on hospital kitchen hygiene using adenosine triphosphate swab testing

PONE-D-20-31068R1

Dear Dr. Takashi Aoyama,

We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements.

Within one week, you’ll receive an e-mail detailing the required amendments. When these have been addressed, you’ll receive a formal acceptance letter and your manuscript will be scheduled for publication.

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Kind regards,

Hans-Uwe Dahms, Ph.D.

Academic Editor

PLOS ONE

Additional Editor Comments (optional):

This MS has now reached a state that makes it acceptable for publication.