PONE-D-20-08468

Correlation and regression analysis between residual gradation and uncorrected visual acuity one year after refractive surgery with LASIK, FS-LASIK, PRK, PRK Xtra techniques and the implantation of ICL® posterior chamber phakic lens.

PLOS ONE

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Reviewer #2: Yes

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Reviewer #1: This paper addresses an important and interesting problem- correlation analysis between residual gradation and UDVA after different refractive surgery methods. But the paper needs very significant improvement before acceptance for publication. My detailed comments are as follows:

1.There was a statistically significant difference in SE in each group before surgery. The correlation between postoperative SE and LogMAR UDVA is closely related to myopic refractive power before surgery, not the refractive surgery techniques. Therefore, it is recommended to add the correlation statistics of postoperative SE and LogMAR UDVA in high, medium and low diopters in each group. At least, choose one of the surgical methods to statistically analyze the correlation between postoperative SE and LogMAR UDVA according to the preoperative SE.

2.The second paragraph of the introduction mainly discusses the cause of retreatment, the choice of retreatment and the risk of retreatment, which has not much relevance to the subject of the article and can be reduced.

Reviewer #2: For upcoming project in this subject, I would recommend a design of the study as a prospective, analytical interventional study to validate the conclusion of this one

You should include the word myopic/ myopic correction in the main title as you exclude hyperopic or pure astigmatic corrections

It is not clear which protocol you use for PRK Xtra, you should specify that Peschke protocol consist of: a total energy level of 2.70 J/cm2 for “X” seconds using which kind of riboflavin ( iso/hypotonic, dextran free?, etc). As you set that postoperative haze was peripheral, could you explain the cause of this observation?.

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Reviewer #1: No

Reviewer #2: No

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Correlation and regression analysis between residual gradation and uncorrected visual acuity one year after refractive surgery with LASIK, FS-LASIK, PRK, PRK Xtra and ICL® techniques in myopic correction.

PONE-D-20-08468R1

Dear Dr. Blanco-Dominguez,

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Kind regards,

Rajiv R. Mohan, Ph.D.

Academic Editor

PLOS ONE

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