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PONE-D-20-10962

Funders’ data-sharing policies in therapeutic research: an audit of commercial and non-commercial funders

PLOS ONE

Dear Dr. GABA,

Thank you for submitting your manuscript to PLOS ONE. After careful consideration, we feel that it has merit but does not fully meet PLOS ONE’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process.

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We look forward to receiving your revised manuscript.

Kind regards,

Despina Koletsi, Dipl.D.S, MSc, Dr. med. dent, MSc, DLSHTM, PGCHE

Academic Editor

PLOS ONE

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Thank you for stating the following in the Competing Interests section:

'I have read the journal's policy and the authors of this manuscript have the following competing interests:

FN received funding from the French National Research Agency for this project.'

a. Please confirm that this does not alter your adherence to all PLOS ONE policies on sharing data and materials, by including the following statement: "This does not alter our adherence to  PLOS ONE policies on sharing data and materials.” (as detailed online in our guide for authors http://journals.plos.org/plosone/s/competing-interests). If there are restrictions on sharing of data and/or materials, please state these.

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Additional Editor Comments (if provided):

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Reviewers' comments:

Reviewer's Responses to Questions

Comments to the Author

1. Is the manuscript technically sound, and do the data support the conclusions?

The manuscript must describe a technically sound piece of scientific research with data that supports the conclusions. Experiments must have been conducted rigorously, with appropriate controls, replication, and sample sizes. The conclusions must be drawn appropriately based on the data presented.

Reviewer #1: Yes

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2. Has the statistical analysis been performed appropriately and rigorously?

Reviewer #1: Yes

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3. Have the authors made all data underlying the findings in their manuscript fully available?

The PLOS Data policy requires authors to make all data underlying the findings described in their manuscript fully available without restriction, with rare exception (please refer to the Data Availability Statement in the manuscript PDF file). The data should be provided as part of the manuscript or its supporting information, or deposited to a public repository. For example, in addition to summary statistics, the data points behind means, medians and variance measures should be available. If there are restrictions on publicly sharing data—e.g. participant privacy or use of data from a third party—those must be specified.

Reviewer #1: Yes

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4. Is the manuscript presented in an intelligible fashion and written in standard English?

PLOS ONE does not copyedit accepted manuscripts, so the language in submitted articles must be clear, correct, and unambiguous. Any typographical or grammatical errors should be corrected at revision, so please note any specific errors here.

Reviewer #1: Yes

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5. Review Comments to the Author

Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters)

Reviewer #1: This research aimed to describe commercial and non-commercial funders' data-sharing policies and to assess the

compliance of funded RCTs with the existing data-sharing policies. I feel this article satisfies the PLOS ONE criteria (see below)

1. The study presents the results of original research. Yes

2. Results reported have not been published elsewhere. Yes

3. Experiments, statistics, and other analyses are performed to a high technical standard and are described in sufficient detail. Yes

4. Conclusions are presented in an appropriate fashion and are supported by the data. Yes

5. The article is presented in an intelligible fashion and is written in standard English. Yes

6. The research meets all applicable standards for the ethics of experimentation and research integrity. Yes

7. The article adheres to appropriate reporting guidelines and community standards for data availability. N/A

Overall, the methodology of this study is robust and appears to be consistent with a previous study published by this research team (Data sharing and reanalysis of randomized controlled trials in leading biomedical journals with a full data sharing policy: survey of studies published in The BMJ and PLOS Medicine). The article is well-written and concise. My only suggestion would be the authors consider amending the title of this study from audit to survey. This article is not really an audit as the results are not compared against an evidence based standard.

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Reviewer #1: No

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Funders’ data-sharing policies in therapeutic research: a survey of commercial and non-commercial funders

PONE-D-20-10962R1

Dear Dr. GABA,

We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements.

Within one week, you’ll receive an e-mail detailing the required amendments. When these have been addressed, you’ll receive a formal acceptance letter and your manuscript will be scheduled for publication.

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Kind regards,

Despina Koletsi, Dipl.D.S, MSc, Dr. med. dent, MSc, DLSHTM, PGCHE

Academic Editor

PLOS ONE

Additional Editor Comments (optional):

All issues raised have been adressed. The manuscript may proceed to publication

Reviewers' comments: