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{"sheet":"Análisis","index":1,"n_rows":44,"n_cols":10,"rows_kept":44,"cut":false,"hidden":false,"merged":[]}
[]
[]
[null,"Seguridad Social?",1,"Seguridad Social = 1, Sector Privado = 0"]
[]
[]
[]
[null,"TASA DESCUENTO 5% (COSTOS Y QALYS)"]
[null,"Resultados (deterministico)",null,null,null,null,null,"Resultados (probabilistico)"]
[null,"Tratamiento","Costos *","QALYs *",null,"Ptes trasplantados",null,"Tratamiento","Costos*","QALYs*"]
[]
[null,"Trasplante",4871487.5550211947,6.1602175844533873,null,814.97743364120754,null,"Trasplante",4788155.0576969106,5.9545376522198987]
[null,"HM Puente",13091756.35420651,6.8968345996109433,null,889.44601804906767,null,"HM Puente",12996739.265418781,6.6912014490199718]
[null,"diferencia",8220268.7991853151,0.73661701515755595,null,null,null,"diferencia",8208584.2077218704,0.7366637968000731]
[]
[null,"ICERs:",null,null,null,null,null,"ICERs:"]
[null,"Tx vs HMPuente",11159488.078655191,"per QALY",null,null,null,"Tx vs HMPuente",11142917.900103675,"per QALY"]
[]
[]
[null,null,null,null,null,null,null,"Resultados (probabilistico)"]
[null,null,null,null,null,null,null,"Tratamiento","Costos*","QALYs*"]
["Determinístico - ESC T.de espera Iguales (3.05 meses)"]
[null,"Tratamiento","Costos *","QALYs *",null,null,null,"Trasplante",4768780.9619464707,5.9653644535286032]
[null,null,null,null,null,null,null,"HM Puente",12907342.727980945,6.7086335233035221]
[null,"Trasplante",4871487.5550211947,6.1602175844533873,null,null,null,"diferencia",8138561.7660344746,0.74326906977491891]
[null,"HM Puente",13273087.261905469,7.0567011713715138]
[null,"diferencia",8401599.7068842743,0.89648358691812646,null,null,null,"ICERs:"]
[null,null,null,null,null,null,null,"Tx vs HMPuente",10949684.437291386,"per QALY"]
[null,"ICERs:"]
[null,"Tx vs HMPuente",9371727.301518986,"per QALY"]
[null,null,null,null,null,null,null,"Resultados (probabilistico) - Sector Privado"]
[null,null,null,null,null,null,null,"Tratamiento","Costos*","QALYs*"]
[]
[null,null,null,null,null,null,null,"Trasplante",5517514.5314739039,5.8833404696369795]
[null,null,null,null,null,null,null,"HM Puente",13944325.435333192,6.6213955098504353]
[null,"SIN DESCUENTO",null,null,null,null,null,"diferencia",8426810.9038592875,0.7380550402134558]
[null,"Resultados (deterministico)"]
[null,"Tratamiento","Costos *","QALYs *",null,null,null,"ICERs:"]
[null,null,null,null,null,null,null,"Tx vs HMPuente",11417591.432506356,"per QALY"]
[null,"Trasplante",7036901.0667249542,10.614996504724308]
[null,"HM Puente",15512379.694206696,11.854386116254728]
[null,"diferencia",8475478.6274817418,1.2393896115304202]
[]
[null,"ICERs:"]
[null,"Tx vs HMPuente",6838429.6177987736,"per QALY"]

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["Parámetros"]
[]
[null,null,null,0,"Probabilístico?","p = 1, d = 0",1,"SegSoc?","SegSoc=1, Priv=0"]
[]
[null,null,null,null,"Analisis de sensibilidad probabilistico"]
["Nombre","Valor","Probabilistico",null,"Deterministico",null,"Error Standard",null,"Lím Inf",null,"Lím Sup",null,"Distribucion","Alfa","Beta","Descripcion",null,null,null,null,null,"Tablas del análisis de sensibilidad - seguridad social",null,null,null,null,"Tabla análisis de sensibilidad - sector privado"]
[]
["Edad",51,51.187951982265034,null,51,null,12.245122966191698,null,39,null,63,null,"Normal",null,null,"Edad de inicio. Fuente: Sintra",null,null,null,null,null,"Edad","Valor Central","LI","LS",null,null,"Edad","Valor Central","LI","LS"]
[null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,51,39,63,null,null,null,51,39,63]
["TasaDesc",4.0741240000000001E-3,2.850260314011901E-4,null,4.0741240000000001E-3,null,4.1573457799593989E-3,null,0,null,8.1482480000000003E-3,null,"Aprox Norm",null,null,"Tasa de descuento de costos",null,null,null,null,"ICER",11159488.078655191,11159488.078655191,10261216.244601354,13044304.432283426,null,"ICER",11159488.078655191,11399620.981209977,10489175.313221585,13307538.601050686]
[null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"CostoHM ","Valor Central","LI","LS",null,null,"CostoHM ","Valor Central","LI","LS"]
["Probabilidades de transición (1 ciclo = 1 mes)",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,8084655.9738781108,5985009.7800000003,9975016.3000000007,null,null,null,8250272.2568920003,6383565.5283920011,10116617.073392]
[null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"ICER",11159488.078655191,11159488.078655191,8309097.5084224176,13725761.036275588,null,"ICER",11159488.078655191,11399620.981209977,8865459.1439345628,13933291.502112627]
["Rama Trasplante"]
["tEE","DIFERENCIA",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"cE (Lista de Espera MM)","Valor Central","LI","LS",null,null,"cE (Lista de Espera MM)","Valor Central","LI","LS"]
["tET",0.32786885245901642,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,159720.0459514799,118930.77,304012.42,null,null,null,219003.33147002154,165794.22173368823,272202.18631835486]
["tEM",7.3999999999999996E-2,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"ICER",11159488.078655191,11159488.078655191,11295749.750076897,10677461.379170606,null,"ICER",11159488.078655191,11399620.981209977]
["tTP","DIFERENCIA"]
["tTM",7.0000000000000007E-2,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"uS2 (uti HM amb)","Valor Central","LI","LS",null,null,"uS2 (uti HM amb)","Valor Central","LI","LS"]
["tPP","DIFERENCIA",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,0.72,0.61199999999999999,0.82799999999999996,null,null,null,0.72,0.61199999999999999,0.82799999999999996]
["tPM",2.4237162596301154E-3,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"ICER",11159488.078655191,11159488.078655191,11855408.553467169,10540739.560083209,null,"ICER",11159488.078655191,11399620.981209977,12110516.462257549,10767558.063566197]
[]
["Rama Puente a Trasplante"]
["pSS","DIFERENCIA",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"uP (uti post Trasplante)","Valor Central","LI","LS",null,null,"uP (uti post Trasplante)","Valor Central","LI","LS"]
["pSM","VARIABLE",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,0.75693183717571777,0.64339206159936013,0.87047161275207541,null,null,null,0.75693183717571777,0.64339206159936013,0.87047161275207541]
["pST",0.14925373134328357,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"ICER",11159488.078655191,11159488.078655191,12189343.780526068,10290096.369795356,null,"ICER",11159488.078655191,11399620.981209977,12451637.398443405,10511521.464874197]
["pTM",7.0000000000000007E-2]
["pTP","DIFERENCIA",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"TasaDesc","Valor Central","LI","LS",null,null,"TasaDesc","Valor Central","LI","LS"]
["pPM",2.4237162596301154E-3,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,4.0741240000000001E-3,0,8.1482480000000003E-3,null,null,null,4.0741240000000001E-3,0,8.1482480000000003E-3]
["pPP","DIFERENCIA",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"ICER",11159488.078655191,11159488.078655191,6838429.6177987736,15926045.595180376,null,"ICER",11159488.078655191,11399620.981209977,7026811.2730087657,16213143.475582778]
[]
["pCS(1)","DIFERENCIA",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"MultMort","Valor Central","LI","LS",null,null,"MultMort","Valor Central","LI","LS"]
["pCS(2)","DIFERENCIA",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,1,0.75,1.25,null,null,null,1,0.75,1.25]
["pCS(3)","DIFERENCIA",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"ICER",11159488.078655191,11159488.078655191,9156993.8803506847,14211186.800575314,null,"ICER",11159488.078655191,11399620.981209977,9381917.8718096241,14478025.332343951]
["pCS(4)","DIFERENCIA"]
["pCS(5)","DIFERENCIA",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"pST (t espera a Tx en rama P - Prob)","Valor Central","LI","LS",null,null,"pST (t espera a Tx en rama P - Prob)","Valor Central","LI","LS"]
["pCS(6)","DIFERENCIA",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,0.14925373134328357,0.1111111111111111,0.32786885245901642,null,null,null,0.14925373134328357,0.1111111111111111,0.32786885245901642]
["pCS(7)","DIFERENCIA",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"ICER",11159488.078655191,11159488.078655191,5049168.3509787833,16615019.399188863,null,"ICER",11159488.078655191,11399620.981209977,5156496.7073775288,16932943.110279817]
[]
["pSC(1)","VARIABLE",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"tET (t espera a Tx en rama Tx - Prob)","Valor Central","LI","LS",null,null,"tET","Valor Central","LI","LS"]
["pSC(2)","VARIABLE",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,0.32786885245901642,0.14925373134328357,0.5,null,null,null,0.32786885245901642,0.14925373134328357,0.5]
["pSC(3)","VARIABLE",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"ICER",11159488.078655191,11159488.078655191,5049168.3509787833,16615019.399188863,null,"ICER",11159488.078655191,11399620.981209977,5156496.7073775288,16932943.110279817]
["pSC(4)","VARIABLE"]
["pSC(5)","VARIABLE"]
["pSC(6)","VARIABLE"]
["pSC(7)",8.1668597151307587E-4]
["pSC(stroke disc)","VARIABLE"]
[]
["pCM(1)","VARIABLE"]
["pCM(2)","VARIABLE"]
["pCM(3)","VARIABLE"]
["pCM(4)","VARIABLE"]
["pCM(5)","VARIABLE"]
["pCM(6)","VARIABLE"]
["pCM(7)","VARIABLE"]
["pCM(stroke disc)","VARIABLE"]
[]
["Costos"]
[null,null,"Seg Social","Sec Privado","Seg Social","Sec Privado","Seg Social","Sec Privado","Seg Social","Sec Privado","Seg Social","Sec Privado"]
["cT",1977548,2240636.7403084007,2846404.7343478804,1977548,2359903.4712082157,384196.01803998754,291565.76430689549,1594018.9288226748,2073147.1589168846,2347029.2871847511,2644605.5560832936,"Normal",null,null,"Costos asociados al trasplante (trasplante + complicaciones)"]
["cP",30295.388440751452,33051.57243973195,33821.922711883701,30295.388440751452,33368.001776758152,1691.2997062700613,491.88897153734274,28713.807734053738,32880.388335457908,32028.69424540623,33844.473004063548,"Normal",null,null,"Costos asociados al post-trasplante"]
["cE",159720.0459514799,65545.834262416101,274953.4364463641,159720.0459514799,219003.33147002154,105285.2375494928,54290.775455058923,56491.93748102156,165794.22173368823,262847.21118177153,272202.18631835486,"Normal",null,null,"Costos asociados al seguimiento MM inotrópicos en UCO."]
["cS",8439.2739908468939,11203.337287131271,12110.279480875341,8439.2739908468939,12335.301016772819,2536.8379698682911,577.63767138195874,6310.4268825135596,11825.360140299672,11282.537938069116,12957.509172321894,"Normal",null,null,"Costos asociados al seguimiento HM ambulatorio"]
["cC_1",159486.74614761697,196202.78826824811,154453.83208803189,159486.74614761697,201941.89510595036,81242.136805913644,45060.706827592818,82544.867397616967,155035.19289761697,241776.52956428361,243352.55539761699,"Normal",null,null,"Costos asociados al sangrado gastrointestinal"]
["cC_2",283684.70353588043,124079.15575095336,442379.70072585187,283684.70353588043,385881.62797164451,152977.15452852804,73268.162646212892,133512.25947164436,313988.05547164433,433341.97280497767,457591.01547164447,"Normal",null,null,"Costos asociados a infección del driveline"]
["cC_3",225471.92966919157,178424.7624889384,354017.85111460497,225471.92966919157,316224.88290419168,155886.06240216154,76516.177686394207,73091.734635858244,241085.1377358583,378622.80263585824,391054.09023585822,"Normal",null,null,"Costos asociados a falla del ventrículo derecho"]
["cC_4",382066.01,442724.22010329971,279477.40524786629,382066.01,271267.121185222,88335.337468269616,60068.624523371072,295068.13,212371.96001855534,468202.21,330104.30068522209,"Normal",null,null,"Costos asociados a ACV"]
["cC_strokeDisc",3943.38,3813.1109345385389,29072.904073839396,3943.38,49539.77921606999,192.44741381741005,10110.344803646078,3840.51,39631.823372855994,4217.7,59447.735059283987,"Normal",null,null,"Costos asociados a ACV discapacitante"]
["cC_5",409473.46,448392.54538949567,641682.88361689157,409473.46,532539.89819569921,182958.56088608236,243614.42179845177,194423.82,258361.82949513989,553016.01,735837.32233465475,"Normal",null,null,"Costos asociados a sepsis"]
["cC_6",121179.12,105517.56529126235,162134.50289828205,121179.12,164135.75303332496,73253.417477307696,35535.476101964072,50097.71,129240.03803332493,193671.77,198888.29136665829,"Normal",null,null,"Costos asociados a arritmia"]
["cC_7",7909064.1616527773,8492339.4065871704,7073593.4877192322,7909064.1616527773,8537615.6022322774,1959598.0428653862,1901382.9490083894,6022525.4863919998,6676122.4873919999,9863267.074583333,10402764.588267,"Normal",null,null,"Costos asociados a falla y recambio"]
["cHM",8084655.9738781108,6388851.0153813455,11165572.919201899,8084655.9738781108,8250272.2568920003,2010534.9986867607,1904653.1336523704,6109235.2463919995,6383565.5283920011,10049811.433475334,10116617.073392,"Normal",null,null,"Costos asociados al dispositivo y su colocación"]
[]
["Utilidades"]
[]
["uT",0.53,0.48158862658781154,null,0.53,null,8.1123939651020008E-2,null,0.45050000000000001,null,0.60950000000000004,null,"Aprox Normal",null,null,"Utilidad Trasplantado - Opinión de experto en base a Long 2017."]
["uP",0.75693183717571777,0.66147318011180045,null,0.75693183717571777,null,0.11585904279052568,null,0.64339206159936013,null,0.87047161275207541,null,"Aprox Normal",null,null,"Utilidad Post-trasplante. Ponderación de utilidades por prob de ocurrencia de complicaciones - ISHLT 2019"]
["uE",0.53,0.49072478171702055,null,0.53,null,8.1123939651020008E-2,null,0.45050000000000001,null,0.60950000000000004,null,"Aprox Normal",null,null,"Utilidad MM dependiente de inotrópicos. Fuente: Long 2014"]
["uS1",0.51,0.3190235477645712,null,0.51,null,7.8062658909472088E-2,null,0.4335,null,0.58650000000000002,null,"Aprox Normal",null,null,"Utilidad HMII 1 mess. Fuente: Long 2014"]
["uS2",0.72,0.66063521445654094,null,0.72,null,0.11020610669572527,null,0.61199999999999999,null,0.82799999999999996,null,"Aprox Normal",null,null,"Utilidad HMII 2 meses o más. Fuente: Long 2014"]
["uC_1",0.6,0.57740170190925688,null,0.6,null,9.1838422246437706E-2,null,0.51,null,0.69,null,"Aprox Normal",null,null,"Utilidad HM II - Sangrado gastrointestinal. Fuente: Long 2014"]
["uC_2",0.6,0.60295194459245471,null,0.6,null,9.1838422246437706E-2,null,0.51,null,0.69,null,"Aprox Normal",null,null,"Utilidad HMII - Infección del driveline. Fuente: Long 2015"]
["uC_3",0.53,0.5452852994259324,null,0.53,null,8.1123939651020008E-2,null,0.45050000000000001,null,0.60950000000000004,null,"Aprox Normal",null,null,"Utilidad HMII - Falla de VD. Fuente: Long 2016"]
["uC_4",0.68,0.84099057823403234,null,0.68,null,0.10408354521262941,null,0.57800000000000007,null,0.78200000000000003,null,"Aprox Normal",null,null,"Utilidad HMII - ACV. Fuente: Duncan & cols."]
["uC_5",0.47,0.38536599205256084,null,0.47,null,7.1940097426376234E-2,null,0.39949999999999997,null,0.54049999999999998,null,"Aprox Normal",null,null,"Utilidad sepsis - Michelle y cols. 2018"]
["uC_6",-0.02,-2.3777481019087617E-2,null,-0.02,null,3.0612807415479238E-3,null,-1.7000000000000001E-2,null,-2.3E-2,null,"Aprox Normal",null,null,"Disutilidad arritmia - Yang cheng y cols 2019"]
["uC_7",0.53,0.63324793812465219,null,0.53,null,8.1123939651020008E-2,null,0.45050000000000001,null,0.60950000000000004,null,"Aprox Normal",null,null,"Utilidad Falla y Recambio. Fuente: Long - Moskowitz y cols"]
["uStrokeDisc",0.68,0.68275384506035453,null,0.68,null,0.10408354521262941,null,0.57800000000000007,null,0.78200000000000003,null,"Aprox Normal",null,null,"Utilidad HMII - ACV. Fuente: Duncan & cols."]
[]
["Parámetros obtenidos de la literatura"]
[]
["Trasplante"]
[]
["tET0",0.32786885245901642,0.2837617658647687,null,0.32786885245901642,null,null,null,0.16393442622950821,null,0.49180327868852464,null,"Aprox Normal",null,null,"Tiempo lista de espera = 3.05 meses Urg/emergencia. Consulta SINTRA-INCUCAI"]
["tEM0",7.3999999999999996E-2,7.2114420526169593E-2,null,7.3999999999999996E-2,null,1.8877897906212204E-2,null,5.5499999999999994E-2,null,9.2499999999999999E-2,null,"Aprox Normal",null,null,"Mortalidad basal OHT elegible. UNOS A y B - Long."]
["tTM0_0",7.0000000000000007E-2,0.123633772495469,null,7.0000000000000007E-2,null,1.7857470992362894E-2,null,5.2500000000000005E-2,null,8.7500000000000008E-2,null,"Aprox Normal",null,null,"16% muerte 1 mes trasplante. Fuente: Registro Favaloro, R & cols. 2011 (N=333)."]
["tPM0",2.4237162596301154E-3,2.2779775738899764E-3,null,2.4237162596301154E-3,null,6.1830632571518681E-4,null,1.8177871947225865E-3,null,3.0296453245376442E-3,null,"Aprox Normal",null,null,"2.87%/año sacado de la pendiente de la kaplan meier de supervivencia - ISHLT"]
[]
["HM III puente"]
[]
["pST_0",0.14925373134328357,0.12917513222202157,null,0.14925373134328357,null,null,null,7.4626865671641784E-2,null,0.22388059701492535,null,"Aprox Norm",null,null,"6.7 meses t de espera electivo. Consulta SINTRA-INCUCAI"]
["MultMort",1,0.9819377291375786,null,1,null,0.12755336423116351,null,0.75,null,1,null,"Aprox Norm",null,null,"Multiplicador de la mortalidad p análisis sensibilidad/probabilístico."]
["dSM0_1",4.0000000000000036E-2,4.8414391041738399E-2,null,4.0000000000000036E-2,null,1.020426913849309E-2,null,3.0000000000000027E-2,null,5.0000000000000044E-2,null,"Aprox Norm",null,null,"Mortalidad 1 mes. INTERMACS."]
["dSM0_3",1.5114219820389518E-2,2.2660113756119364E-2,null,1.5114219820389518E-2,null,3.8557391716400303E-3,null,1.1335664865292139E-2,null,1.8892774775486898E-2,null,"Aprox Norm",null,null,"Mortalidad 3 meses (mensualizada). INTERMACS."]
["dSM0_6",6.7116116207313059E-3,7.5646997184064934E-3,null,6.7116116207313059E-3,null,1.7121772832744998E-3,null,5.0337087155484794E-3,null,8.3895145259141324E-3,null,"Aprox Norm",null,null,"Mortalidad 6 meses (mensualizada). INTERMACS."]
["dSM0_12",6.7805732205052927E-3,8.0636323473301155E-3,null,6.7805732205052927E-3,null,1.7297698513823701E-3,null,5.0854299153789695E-3,null,8.4757165256316158E-3,null,"Aprox Norm",null,null,"Mortalidad 12 meses (mensualizada). INTERMACS."]
["dSM0_24",7.8284203424832111E-3,6.4690093397554334E-3,null,7.8284203424832111E-3,null,1.9970827025988219E-3,null,5.8713152568624083E-3,null,9.7855254281040138E-3,null,"Aprox Norm",null,null,"Mortalidad 18 meses (mensualizada). INTERMACS."]
["dSM0_36",6.9243826282994192E-3,1.1099006810114071E-2,null,6.9243826282994192E-3,null,1.7664565989268344E-3,null,5.1932869712245644E-3,null,8.655478285374274E-3,null,"Aprox Norm",null,null,"Mortalidad 24 meses (mensualizada). INTERMACS."]
["dSM0_48",6.9243826282994192E-3,5.2114188494568085E-3,null,6.9243826282994192E-3,null,1.7664565989268344E-3,null,5.1932869712245644E-3,null,8.655478285374274E-3,null,"Aprox Norm",null,null,"Mortalidad 48 meses (mensualizada). INTERMACS."]
["dSM0_60",7.8284203424832111E-3,7.1756307861215226E-3,null,7.8284203424832111E-3,null,1.9970827025988219E-3,null,5.8713152568624083E-3,null,9.7855254281040138E-3,null,"Aprox Norm",null,null,"Mortalidad 60 meses (mensualizada). INTERMACS."]
["dSC1_0a",1.6751639503123084E-2,8.5448244090648492E-3,null,1.6751639503123084E-2,null,4.2734559500220114E-3,null,1.2563729627342313E-2,null,2.0939549378903854E-2,null,"Aprox Norm",null,null,"HMT III - sangrado gastrointestinal. Fuente: Mehra 2019. Mom-3"]
["dSC1_0b",5.2458245006895554E-3,6.7273028009519663E-3,null,5.2458245006895554E-3,null,1.3382451264584328E-3,null,3.9343683755171666E-3,null,6.5572806258619443E-3,null,"Aprox Norm",null,null,"HMT III - sangrado gastrointestinal. Fuente: Mehra 2019. Mom-4"]
["dSC2_0a",1.5879054751426258E-2,1.8977148659465502E-2,null,1.5879054751426258E-2,null,4.0508537087105227E-3,null,1.1909291063569694E-2,null,1.9848818439282823E-2,null,"Aprox Norm",null,null,"HMT III - infección del driveline. Fuente: Mehra 2019. Mom-3"]
["dSC2_0b",4.9890141313944092E-3,4.411139807834568E-3,null,4.9890141313944092E-3,null,1.272731073312346E-3,null,3.7417605985458069E-3,null,6.2362676642430115E-3,null,"Aprox Norm"]
["dSC3_0a",2.4375655207887648E-2,2.2772717155799236E-2,null,2.4375655207887648E-2,null,6.2183936542099024E-3,null,1.8281741405915736E-2,null,3.046956900985956E-2,null,"Aprox Norm",null,null,"HMT III - falla de VD (requiere otro dispositivo). Fuente: Mehra 2019. Mom-3"]
["dSC3_0b",7.4147744682232508E-3,4.2813676199198224E-3,null,7.4147744682232508E-3,null,1.8915588568744243E-3,null,5.5610808511674381E-3,null,9.2684680852790635E-3,null,"Aprox Norm"]
["dSC_4_0_1 m",3.6999999999999998E-2,4.9921042656212167E-2,null,3.6999999999999998E-2,null,9.4389489531061018E-3,null,2.7749999999999997E-2,null,4.6249999999999999E-2,null,"Aprox Norm",null,null,"HMT III - ACV (disc+no disc). Fuente: Colombo, 2018"]
["dSC4_0_1 a 6m",7.7182260034300842E-3,6.1640460188560004E-3,null,7.7182260034300842E-3,null,1.9689713852679099E-3,null,5.7886695025725632E-3,null,9.6477825042876053E-3,null,"Aprox Norm",null,null,"HMT III - ACV (disc+no disc). Fuente: Colombo, 2019"]
["dSC4_0_+6m - 2a",1.6907472673166613E-3,1.7049028182605146E-3,null,1.6907472673166613E-3,null,4.3132100402177296E-4,null,1.2680604504874959E-3,null,2.1134340841458266E-3,null,"Aprox Norm",null,null,"HMT III - ACV (disc+no disc). Fuente: Colombo, 2019"]
["dSC5_0a",9.9978690546089766E-3,1.2016130656766265E-2,null,9.9978690546089766E-3,null,2.5505236661160346E-3,null,7.4984017909567324E-3,null,1.2497336318261221E-2,null,"Aprox Norm",null,null,"HMT III - infección (sepsis). Mehra 2019. Mom-3"]
["dSC5_0b",3.2114610995013226E-3,3.3011250029717143E-3,null,3.2114610995013226E-3,null,8.1926533467781011E-4,null,2.408595824625992E-3,null,4.0143263743766533E-3,null,"Aprox Norm",null,null,"HMT III - infección (sepsis). Mehra 2019. Mom-4"]
["dSC6_0a",1.4017144326536779E-2,1.3234536983859639E-2,null,1.4017144326536779E-2,null,3.5758678315270659E-3,null,1.0512858244902584E-2,null,1.7521430408170974E-2,null,"Aprox Norm",null,null,"HMT III - arritmia (cualquier tipo). Mehra 2019. Mom-4"]
["dSC6_0b",4.4350800981894922E-3,3.1382020644455479E-3,null,4.4350800981894922E-3,null,1.1314187743174976E-3,null,3.3263100736421192E-3,null,5.5438501227368653E-3,null,"Aprox Norm"]
["dSC7_0",1.9417475728155338E-2,1.3510563359974411E-2,null,1.9417475728155338E-2,null,4.9535287080063493E-3,null,1.4563106796116504E-2,null,2.4271844660194171E-2,null,"Aprox Norm",null,null,"HM III - falla y recambio del dispositivo. Mehra 2019. Mom-3."]
["Strokedisc0a",3.2114610995013226E-3,3.5871444542766402E-3,null,3.2114610995013226E-3,null,8.1926533467781011E-4,null,2.408595824625992E-3,null,4.0143263743766533E-3,null,"Aprox Norm",null,null,"HMT III - ACV discapacitante. Fuente: Mehra 2019. Mom-3"]
["Strokedisc0b",1.0579137788324644E-3,9.0716903406168369E-4,null,1.0579137788324644E-3,null,2.6988092311316779E-4,null,7.934353341243483E-4,null,1.3223922235405805E-3,null,"Aprox Norm",null,null,"HMT III - ACV discapacitante. Fuente: Mehra 2019. Mom-4"]
[]
["Parámetros arbitrarios de variación en tiempos de trasplante"]
[]
[null,null,"Particiones "]
["tET dif LS-LI",0.32786885245901642,3.2786885245901641E-2]
["pST dif LS-LI",0.14925373134328357,1.4925373134328356E-2]
[]
["VarTiempoTx0",3.6547338588754452]
["VarTiempoTx",3.6547338588754452]

{"sheet":"Tabla de Vida","index":3,"n_rows":105,"n_cols":7,"rows_kept":105,"cut":false,"hidden":false,"merged":[]}
["TABLA DE MORTALIDAD",null,null,null,null," Tablas abreviadas de mortalidad por sexo y edad 2008-2010: total del país y provincias.  Serie Análisis Demográfico N° 37."]
[null,null,null,null,null,"Fuente: INDEC. Programa de Análisis Demográfico, Dirección de Estadísticas Poblacionales."]
[]
["Edad","Varón","Mujer","Total","Probabilidad ponderada total","Riesgo mensual","Proba mensual"]
[0,349040,336317,685357,1.0988979303267725E-2,9.2081701239819867E-4,9.203931905105156E-4]
[1,341082,329761,670843,8.4861702952764191E-4,7.0748109066630043E-5,7.0745606478128664E-5]
[2,342283,331229,673512,6.0017985775541764E-4,5.0030003148620918E-5,5.0028751668929061E-5]
[3,329846,318225,648071,4.5169918008536368E-4,3.765010224090033E-5,3.7649393484717741E-5]
[4,335721,324148,659869,3.3666732195940599E-4,2.8060333927104229E-5,2.8059940239577585E-5]
[5,343450,332680,676130,2.6817525053067737E-4,2.2350934661946134E-5,2.2350684881655702E-5]
[6,344980,333927,678907,2.4989799343315443E-4,2.0827435261634094E-5,2.0827218372154732E-5]
[7,343350,332864,676214,2.3468948944616123E-4,1.9559752777831691E-5,1.9559561487136889E-5]
[8,341649,330490,672139,2.2216957057517265E-4,1.8516187824185499E-5,1.8516016400682567E-5]
[9,344323,333506,677829,2.1380167766713251E-4,1.7818711375339546E-5,1.7818552623061201E-5]
[10,360737,349672,710409,2.1666188315455924E-4,1.8057113144264706E-5,1.8056950115585835E-5]
[11,350484,338026,688510,2.3452629598743133E-4,1.9546150131647991E-5,1.9545959106914701E-5]
[12,351253,338079,689332,2.6303622473131534E-4,2.19225687355515E-5,2.1922328437784522E-5]
[13,342560,335713,678273,3.3435406008617012E-4,2.7867497405625748E-5,2.7867109110513155E-5]
[14,374338,362584,736922,4.4115035779646831E-4,3.677064110358192E-5,3.6769965071847821E-5]
[15,362748,355887,718635,5.590468875310634E-4,4.66002677089162E-5,4.6599181933282274E-5]
[16,353088,344852,697940,6.731167067169331E-4,5.6111945956550191E-5,5.6110371710715867E-5]
[17,350634,344221,694855,7.7023314405540177E-4,6.4210827167293912E-5,6.4208765696238679E-5]
[18,359286,354323,713609,8.4148680391531855E-4,7.0153421056686212E-5,7.015096036300239E-5]
[19,359305,357723,717028,8.9077797755093716E-4,7.4264579668123851E-5,7.4261822122445587E-5]
[20,349212,346815,696027,9.3876625093408227E-4,7.8267263994825906E-5,7.8264201192390637E-5]
[21,325664,325302,650966,9.846480373060006E-4,8.2094426802978326E-5,8.2091057147737345E-5]
[22,324165,325199,649364,1.0198298775330032E-3,8.5029188154354607E-5,8.5025573275387956E-5]
[23,323799,326737,650536,1.0431550748178956E-3,8.6974961645565571E-5,8.6971179433237289E-5]
[24,325616,327640,653256,1.0603985501367757E-3,8.8413430870747754E-5,8.8409522518539951E-5]
[25,311955,316121,628076,1.0728581766844482E-3,8.9452841748194581E-5,8.9448840962069731E-5]
[26,302205,306851,609056,1.0866197531224355E-3,9.0600879365657636E-5,9.0596775229934146E-5]
[27,303535,307445,610980,1.099408252757452E-3,9.1667753777263563E-5,9.1663552417076133E-5]
[28,321564,327716,649280,1.1091128942775075E-3,9.2477367928928917E-5,9.2473092028977355E-5]
[29,312847,320270,633117,1.1206318878812555E-3,9.3438355441030215E-5,9.3433990213886986E-5]
[30,328197,336373,664570,1.1355445049455978E-3,9.4682477008602105E-5,9.4677994764369444E-5]
[31,312003,321997,634000,1.1558472845671676E-3,9.6376315934765844E-5,9.6371671886807952E-5]
[32,302446,314231,616677,1.1876722433898893E-3,9.9031507083035237E-5,9.9026603625151921E-5]
[33,299524,310863,610387,1.2357018298328624E-3,1.0303882823982125E-4,1.030335199221355E-4]
[34,281172,291907,573079,1.2975651726735849E-3,1.0820064494148456E-4,1.0819479146284561E-4]
[35,282604,293989,576593,1.3712675086914883E-3,1.143507130304598E-4,1.1434417523692453E-4]
[36,262693,274036,536729,1.4557217587503838E-3,1.2139852925664279E-4,1.213911607533813E-4]
[37,259598,269801,529399,1.5536653578407879E-3,1.2957279561998816E-4,1.2956440142786185E-4]
[38,256537,267319,523856,1.6627775486600365E-3,1.3868012479948384E-4,1.3867050915550294E-4]
[39,250096,261762,511858,1.7856916580463486E-3,1.489406588291011E-4,1.4892956771983545E-4]
[40,248912,260630,509542,1.9298808490278096E-3,1.6097878903793925E-4,1.6096583264790798E-4]
[41,228038,238820,466858,2.0938367923777896E-3,1.7466932777895821E-4,1.7465407398009614E-4]
[42,222817,234737,457554,2.2700982560691419E-3,1.8938990294171539E-4,1.8937196980617355E-4]
[43,213101,225598,438699,2.459787947643453E-3,2.0523484968469597E-4,2.0521379045368437E-4]
[44,213019,225103,438122,2.6706249130595671E-3,2.2284978280784408E-4,2.2282495363945554E-4]
[45,220704,232876,453580,2.9035962655970839E-3,2.4231832324949666E-4,2.4228896653588627E-4]
[46,215428,227881,443309,3.1691613677973904E-3,2.6451614957333913E-4,2.6448116826105483E-4]
[47,215468,228471,443939,3.4814673338601715E-3,2.9062847866082492E-4,2.9058625029554364E-4]
[48,211989,222824,434813,3.8542552332935243E-3,3.2180850130724971E-4,3.2175672650547327E-4]
[49,203879,216830,420709,4.267752872523462E-3,3.5640714363143161E-4,3.5634363815029158E-4]
[50,212341,226436,438777,4.7236725996745478E-3,3.9457203327185786E-4,3.9449419996440138E-4]
[51,194858,209182,404040,5.2099257665555038E-3,4.352953960834862E-4,4.3520066878788288E-4]
[52,194065,207388,401453,5.7467412244377753E-3,4.8027643981836046E-4,4.8016112555071544E-4]
[53,194635,207971,402606,6.3238559860991344E-3,5.2866135538800856E-4,5.2852163859573587E-4]
[54,190297,205820,396117,6.9320206314807779E-3,5.7967989179806838E-4,5.7951190986971213E-4]
[55,187643,204200,391843,7.5970937572473847E-3,6.3550822245262415E-4,6.3530632987263136E-4]
[56,181432,197213,378645,8.3177232426040297E-3,6.9604237720389671E-4,6.9580019590120834E-4]
[57,178927,194843,373770,9.0692258070081307E-3,7.5921679913112949E-4,7.589286669799078E-4]
[58,175414,191968,367382,9.8467787996078995E-3,8.2463157830712239E-4,8.2429166312847357E-4]
[59,170154,187156,357310,1.0666568219130396E-2,8.9365532116794709E-4,8.932561301733255E-4]
[60,173319,194935,368254,1.1507297945893899E-2,9.6450160394768471E-4,9.6403662177968474E-4]
[61,154790,171821,326611,1.2495073374679972E-2,1.0478161026365978E-3,1.0472673350300221E-3]
[62,151211,171678,322889,1.350880328416598E-2,1.1334064428450369E-3,1.1327643803581422E-3]
[63,144736,164058,308794,1.4695662402582792E-2,1.2337261126669683E-3,1.2329653854815659E-3]
[64,136858,157784,294642,1.595318405648331E-2,1.3401504902725854E-3,1.3392528896224443E-3]
[65,138149,162109,300258,1.7323088266219352E-2,1.4562407178935323E-3,1.4551809138849681E-3]
[66,122707,145289,267996,1.8822748997559945E-2,1.5835126449793187E-3,1.5822595503486303E-3]
[67,115871,139122,254993,2.0404205924832192E-2,1.717937285485702E-3,1.7164624758916336E-3]
[68,109009,132571,241580,2.2087711845147323E-2,1.8612748235408852E-3,1.8595437257393765E-3]
[69,102833,125401,228234,2.3942835811945784E-2,2.0195103682818733E-3,2.0174725292612106E-3]
[70,105949,134546,240495,2.5790731907157104E-2,2.1774286760596422E-3,2.1750597979063313E-3]
[71,91197,116686,207883,2.7996674066846076E-2,2.3663377321353472E-3,2.3635401621043828E-3]
[72,84638,111644,196282,3.0402955904512838E-2,2.5728926877600792E-3,2.5695856362063507E-3]
[73,80445,108495,188940,3.3226431107779598E-2,2.8159141067455157E-3,2.8119531394040775E-3]
[74,76209,106088,182297,3.6393535330748801E-2,3.0893582826438276E-3,3.0845911257599834E-3]
[75,75096,106217,181313,3.979303272832517E-2,3.3838689040533864E-3,3.3781500720846402E-3]
[76,65769,95524,161293,4.3447673900373615E-2,3.7016488163436104E-3,3.6948061600045046E-3]
[77,62633,94006,156639,4.7929570531408103E-2,4.0930221994134441E-3,4.0846572006512094E-3]
[78,61294,94630,155924,5.3641336211309065E-2,4.5944703822714227E-3,4.5839319489088259E-3]
[79,56689,89802,146491,6.0468451974996992E-2,5.1978234251823388E-3,5.1843381158718227E-3]
[80,52487,90998,143485,6.7731104482991605E-2,5.844499283801965E-3,5.8274534222055863E-3]
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