Q8K1B8	URP2_MOUSE	Fermitin family homolog 3	19234461	Kindlin-3 is required for beta2 integrin-mediated leukocyte adhesion to endothelial cells.

P92966	RSP41_ARATH	Arginine/serine-rich-splicing factor RSP41	16807317	Phosphoproteomics reveals extensive in vivo phosphorylation of Arabidopsis proteins involved in RNA metabolism.

Q39232	SUC1_ARATH	Sucrose transport protein SUC1	7920705	SUC1 and SUC2: two sucrose transporters from Arabidopsis thaliana; expression and characterization in baker's yeast and identification of the histidine-tagged protein.

O23277	PRD1_ARATH	Protein PRD1	17762870	AtPRD1 is required for meiotic double strand break formation in Arabidopsis thaliana.

Q8IWF2	FXRD2_HUMAN	FAD-dependent oxidoreductase domain-containing protein 2	19706418	A luminal flavoprotein in endoplasmic reticulum-associated degradation.

P34478	GEI13_CAEEL	Gex-3-interacting protein 13	11922622	Isolation of the interacting molecules with GEX-3 by a novel functional screening.

Q9UBE8	NLK_HUMAN	Serine/threonine-protein kinase NLK	10863097	Characterization of the Fugu rubripes NLK and FN5 genes flanking the NF1 (Neurofibromatosis type 1) gene in the 5' direction and mapping of the human counterparts.

P62304	RUXE_HUMAN	Small nuclear ribonucleoprotein E	2974536	The complete primary structure of the human snRNP E protein.

Q6TMG5	NEMO_RAT	NF-kappa-B essential modulator	12968033	Two carboxyl-terminal activation regions of Epstein-Barr virus latent membrane protein 1 activate NF-kappaB through distinct signaling pathways in fibroblast cell lines.

O95243	MBD4_HUMAN	Methyl-CpG-binding domain protein 4	10097147	MED1, a novel human methyl-CpG-binding endonuclease, interacts with DNA mismatch repair protein MLH1.

O97764	QOR_BOVIN	Zeta-crystallin	9154917	Guinea pig and bovine zeta-crystallins have distinct functional characteristics highlighting replacements in otherwise similar structures.

Q61754	K1B24_MOUSE	Kallikrein 1-related peptidase b24	11082197	Cloning and characterization of mouse Klk27, a novel tissue kallikrein expressed in testicular Leydig cells and exhibiting chymotrypsin-like specificity.

O95633	FSTL3_HUMAN	Follistatin-related protein 3	17868029	AF10-dependent transcription is enhanced by its interaction with FLRG.

P49792	RBP2_HUMAN	E3 SUMO-protein ligase RanBP2	7603572	A giant nucleopore protein that binds Ran/TC4.

Q12163	NBP2_YEAST	NAP1-binding protein 2	14685261	Nbp2 targets the Ptc1-type 2C Ser/Thr phosphatase to the HOG MAPK pathway.

Q91ZR5	CTSR1_MOUSE	Cation channel sperm-associated protein 1	17227845	All four CatSper ion channel proteins are required for male fertility and sperm cell hyperactivated motility.

Q80SU6	NPT2C_MOUSE	Sodium-dependent phosphate transport protein 2C	12690469	Cloning, gene structure and dietary regulation of the type-IIc Na/Pi cotransporter in the mouse kidney.

P23359	BMP7_MOUSE	Bone morphogenetic protein 7	15843411	Sirenomelia in Bmp7 and Tsg compound mutant mice: requirement for Bmp signaling in the development of ventral posterior mesoderm.

O08587	NUP50_RAT	Nuclear pore complex protein Nup50	10891499	Nup50, a nucleoplasmically oriented nucleoporin with a role in nuclear protein export.

O15084	ANR28_HUMAN	Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A	18186651	Protein phosphatase 6 regulatory subunits composed of ankyrin repeat domains.

Q39253	CAX1_ARATH	Vacuolar cation/proton exchanger 1	8710949	CAX1, an H+/Ca2+ antiporter from Arabidopsis.

Q80VW5	WHRN_MOUSE	Whirlin	15590699	Mutant analysis reveals whirlin as a dynamic organizer in the growing hair cell stereocilium.

Q15758	AAAT_HUMAN	Neutral amino acid transporter B(0)	10051606	The RD114/simian type D retrovirus receptor is a neutral amino acid transporter.

P62509	ERR3_MOUSE	Estrogen-related receptor gamma	10428842	Hormone-independent transcriptional activation and coactivator binding by novel orphan nuclear receptor ERR3.

P33527	MRP1_HUMAN	Multidrug resistance-associated protein 1	1360704	Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line.

P19086	GNAZ_HUMAN	Guanine nucleotide-binding protein G(z) subunit alpha	3129724	Identification of a GTP-binding protein alpha subunit that lacks an apparent ADP-ribosylation site for pertussis toxin.

Q9H8T0	AKTIP_HUMAN	AKT-interacting protein	14749367	Regulation of apoptosis by the Ft1 protein, a new modulator of protein kinase B/Akt.

Q02793	SKI8_YEAST	Antiviral protein SKI8	14992724	Antiviral protein Ski8 is a direct partner of Spo11 in meiotic DNA break formation, independent of its cytoplasmic role in RNA metabolism.

P52286	SKP1_YEAST	Suppressor of kinetochore protein 1	15090617	Sgt1p and Skp1p modulate the assembly and turnover of CBF3 complexes required for proper kinetochore function.

Q16143	SYUB_HUMAN	Beta-synuclein	9806846	Genomic organization and expression of the human beta-synuclein gene (SNCB).

Q08226	CRT10_YEAST	Protein CRT10	16600900	Identification and characterization of CRT10 as a novel regulator of Saccharomyces cerevisiae ribonucleotide reductase genes.

Q9FMV1	UMP7_ARATH	Uncharacterized protein At5g63510, mitochondrial	11743114	Proteomic approach to identify novel mitochondrial proteins in Arabidopsis.

Q9VIR2	TOTF_DROME	Protein Turandot F	11409894	A family of Turandot-related genes in the humoral stress response of Drosophila.

P01130	LDLR_HUMAN	Low-density lipoprotein receptor	6091915	The human LDL receptor: a cysteine-rich protein with multiple Alu sequences in its mRNA.

O42924	EAF7_SCHPO	Probable chromatin modification-related protein eaf7	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q06561	UNC52_CAEEL	Basement membrane proteoglycan	8393416	Products of the unc-52 gene in Caenorhabditis elegans are homologous to the core protein of the mammalian basement membrane heparan sulfate proteoglycan.

Q04049	POLH_YEAST	DNA polymerase eta	10713149	Specificity of DNA lesion bypass by the yeast DNA polymerase eta.

P83960	BNCA_BENHI	Alpha-benincasin	12576080	Purification and characterization of alpha- and beta-benincasins, arginine/glutamate-rich peptides with translation-inhibiting activity from wax gourd seeds.

Q92845	KIFA3_HUMAN	Kinesin-associated protein 3	9506951	Complex formation of SMAP/KAP3, a KIF3A/B ATPase motor-associated protein, with a human chromosome-associated polypeptide.

P61223	RAP1B_BOVIN	Ras-related protein Rap-1b	2105724	Molecular cloning of smg p21B and identification of smg p21 purified from bovine brain and human platelets as smg p21B.

Q92903	CDS1_HUMAN	Phosphatidate cytidylyltransferase 1	9115637	Isolation and expression of an isoform of human CDP-diacylglycerol synthase cDNA.

P50078	TOS2_YEAST	Protein TOS2	14872283	Separate membrane targeting and anchoring domains function in the localization of the S. cerevisiae Cdc24p guanine nucleotide exchange factor.

P82921	RT21_HUMAN	28S ribosomal protein S21, mitochondrial	11279123	The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present.

Q9NTG1	PKDRE_HUMAN	Polycystic kidney disease and receptor for egg jelly-related protein	9949214	Identification of a human homologue of the sea urchin receptor for egg jelly: a polycystic kidney disease-like protein.

P0A6D0	ARGR_ECOLI	Arginine repressor	3149585	The arginine repressor is essential for plasmid-stabilizing site- specific recombination at the ColE1 cer locus.

P08459	SPS2_YEAST	Sporulation-specific protein 2	15590821	Morphogenetic pathway of spore wall assembly in Saccharomyces cerevisiae.

P48996	DPY27_CAEEL	Chromosome condensation protein dpy-27	7954812	DPY-27: a chromosome condensation protein homolog that regulates C. elegans dosage compensation through association with the X chromosome.

Q15513	SPHAR_HUMAN	Protein SPHAR	7799938	Irreversible repression of DNA synthesis in Fanconi anemia cells is alleviated by the product of a novel cyclin-related gene.

Q62997	GFRA1_RAT	GDNF family receptor alpha-1	8674117	GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF.

P10868	GAMT_RAT	Guanidinoacetate N-methyltransferase	3277179	Molecular cloning, sequence analysis, and expression in Escherichia coli of the cDNA for guanidinoacetate methyltransferase from rat liver.

P16619	CL3L1_HUMAN	C-C motif chemokine 3-like 1	2271120	Three human homologs of a murine gene encoding an inhibitor of stem cell proliferation.

Q24046	ATPB1_DROME	Sodium/potassium-transporting ATPase subunit beta-1	9648860	Functional analysis and tissue-specific expression of Drosophila Na+,K+-ATPase subunits.

P16333	NCK1_HUMAN	Cytoplasmic protein NCK1	2107526	Nck, a melanoma cDNA encoding a cytoplasmic protein consisting of the src homology units SH2 and SH3.

P36120	DBP7_YEAST	ATP-dependent RNA helicase DBP7	9582098	Dbp7p, a putative ATP-dependent RNA helicase from Saccharomyces cerevisiae, is required for 60S ribosomal subunit assembly.

P86413	OSR1_XENLA	Protein odd-skipped-related 1	17011543	Odd-skipped genes encode repressors that control kidney development.

O80920	PYL4_ARATH	Abscisic acid receptor PYL4	19898420	A gate-latch-lock mechanism for hormone signalling by abscisic acid receptors.

P55828	RS20_DROME	40S ribosomal protein S20	9373141	Identification and characterization of the gene for Drosophila S20 ribosomal protein.

Q9Y6X3	SCC4_HUMAN	Cohesin loading complex subunit SCC4 homolog	16682347	Human Scc4 is required for cohesin binding to chromatin, sister- chromatid cohesion, and mitotic progression.

Q86US8	EST1A_HUMAN	Telomerase-binding protein EST1A	12699629	Functional conservation of the telomerase protein Est1p in humans.

Q9V521	PRPA3_DROME	Phenoloxidase subunit A3	19141111	Identification of the gene encoding pro-phenoloxidase A(3) in the fruitfly, Drosophila melanogaster.

P23645	BIB_DROME	Neurogenic protein big brain	11923418	Regulated cationic channel function in Xenopus oocytes expressing Drosophila big brain.

P53598	SUCA_YEAST	Succinyl-CoA ligase [ADP-forming] subunit alpha, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q16850	CP51A_HUMAN	Lanosterol 14-alpha demethylase	8619637	The ubiquitously expressed human CYP51 encodes lanosterol 14 alpha- demethylase, a cytochrome P450 whose expression is regulated by oxysterols.

P32695	DUSA_ECOLI	tRNA-dihydrouridine synthase A	11983710	Identification of the tRNA-dihydrouridine synthase family.

Q9WU68	PKHB1_RAT	Pleckstrin homology domain-containing family B member 1	10923244	KPL1, which encodes a novel PH domain-containing protein, is induced during ciliated cell differentiation of rat tracheal epithelial cells.

Q9GZV9	FGF23_HUMAN	Fibroblast growth factor 23	11409890	FGF-23 inhibits renal tubular phosphate transport and is a PHEX substrate.

P38717	SIP3_YEAST	Protein SIP3	8127709	Analysis of the SIP3 protein identified in a two-hybrid screen for interaction with the SNF1 protein kinase.

P50109	PSP2_YEAST	Protein PSP2	14562095	Global analysis of protein localization in budding yeast.

O13965	MUG70_SCHPO	Meiotically up-regulated gene 70 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9BY49	PECR_HUMAN	Peroxisomal trans-2-enoyl-CoA reductase	10811639	Molecular cloning and expression of mammalian peroxisomal trans-2- enoyl-coenzyme A reductase cDNAs.

Q04695	K1C17_HUMAN	Keratin, type I cytoskeletal 17	1281771	Characterization of the human gene encoding cytokeratin 17 and its expression pattern.

Q08231	THP1_YEAST	Nuclear mRNA export protein THP1	12702719	Nab2p and the Thp1p-Sac3p complex functionally interact at the interface between transcription and mRNA metabolism.

Q91572	CPE1A_XENLA	Cytoplasmic polyadenylation element-binding protein 1-A	10635326	Maskin is a CPEB-associated factor that transiently interacts with eIF-4E.

Q91WZ8	DTBP1_MOUSE	Dysbindin	14688250	Myospryn is a novel binding partner for dysbindin in muscle.

O88763	PK3C3_RAT	Phosphatidylinositol 3-kinase catalytic subunit type 3	11171063	Overexpression of a rat kinase-deficient phosphoinositide 3-kinase, Vps34p, inhibits cathepsin D maturation.

O75023	LIRB5_HUMAN	Leukocyte immunoglobulin-like receptor subfamily B member 5	9548455	A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules.

Q62687	S6A18_RAT	Sodium-dependent neutral amino acid transporter B(0)AT3	7943364	Molecular characterization of ROSIT, a renal osmotic stress-induced Na(+)-Cl(-)-organic solute cotransporter.

O74700	TIM9_YEAST	Mitochondrial import inner membrane translocase subunit TIM9	11483513	Functional reconstitution of the import of the yeast ADP/ATP carrier mediated by the TIM10 complex.

Q13439	GOGA4_HUMAN	Golgin subfamily A member 4	8626529	Molecular characterization of trans-Golgi p230: a human peripheral membrane protein encoded by a gene on chromosome 6p12-22 contains extensive coiled-coil alpha-helical domains and a granin motif.

P11532	DMD_HUMAN	Dystrophin	8576247	The three human syntrophin genes are expressed in diverse tissues, have distinct chromosomal locations, and each bind to dystrophin and its relatives.

Q06710	PAX8_HUMAN	Paired box protein Pax-8	19010321	TAZ is a coactivator for Pax8 and TTF-1, two transcription factors involved in thyroid differentiation.

P54132	BLM_HUMAN	Bloom syndrome protein	9388480	BLM (the causative gene of Bloom syndrome) protein translocation into the nucleus by a nuclear localization signal.

Q6YNI2	GPR6_MOUSE	G-protein coupled receptor 6	14592418	Sphingosine-1-phosphate is a high-affinity ligand for the G protein- coupled receptor GPR6 from mouse and induces intracellular Ca2+ release by activating the sphingosine-kinase pathway.

Q6NLC1	AB2D_ARATH	ABC transporter D family member 2, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

P46086	KIME_ARATH	Mevalonate kinase	7958957	Isolation and characterization of a cDNA encoding Arabidopsis thaliana mevalonate kinase by genetic complementation in yeast.

Q6DI48	DLLA_DANRE	Delta-like protein A	15013799	Three modules of zebrafish Mind bomb work cooperatively to promote Delta ubiquitination and endocytosis.

P76535	MURQ_ECOLI	N-acetylmuramic acid 6-phosphate etherase	15983044	Scission of the lactyl ether bond of N-acetylmuramic acid by Escherichia coli 'etherase'.

P16070	CD44_HUMAN	CD44 antigen	1991450	The hematopoietic and epithelial forms of CD44 are distinct polypeptides with different adhesion potentials for hyaluronate- bearing cells.

P46481	AAEB_ECOLI	p-hydroxybenzoic acid efflux pump subunit AaeB	15489430	Characterization of the Escherichia coli AaeAB efflux pump: a metabolic relief valve?

Q42029	PSBP1_ARATH	Oxygen-evolving enhancer protein 2-1, chloroplastic	11719511	Proteome map of the chloroplast lumen of Arabidopsis thaliana.

P23508	CRCM_HUMAN	Colorectal mutant cancer protein	19555689	MCC, a new interacting protein for Scrib, is required for cell migration in epithelial cells.

Q9H343	O51I1_HUMAN	Olfactory receptor 51I1	11121057	Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.

O75841	UPK1B_HUMAN	Uroplakin-1b	9818021	Expression of uroplakin Ib and uroplakin III genes in tissues and peripheral blood of patients with transitional cell carcinoma.

Q04233	GIS4_YEAST	Protein GIS4	10628841	Yeast genes GIS1-4: multicopy suppressors of the Gal- phenotype of snf1 mig1 srb8/10/11 cells.

Q13838	UAP56_HUMAN	Spliceosome RNA helicase BAT1	17190602	Human mRNA export machinery recruited to the 5' end of mRNA.

O75175	CNOT3_HUMAN	CCR4-NOT transcription complex subunit 3	12207886	TBP-interacting protein 120B, which is induced in relation to myogenesis, binds to NOT3.

Q02809	PLOD1_HUMAN	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1	1577494	Cloning of human lysyl hydroxylase: complete cDNA-derived amino acid sequence and assignment of the gene (PLOD) to chromosome 1p36.3- p36.2.

Q9FGM1	PYL8_ARATH	Abscisic acid receptor PYL8	19769575	Closely related receptor complexes differ in their ABA selectivity and sensitivity.

P62244	RS15A_HUMAN	40S ribosomal protein S15a	9582194	A map of 75 human ribosomal protein genes.

P47102	GEA1_YEAST	ARF guanine-nucleotide exchange factor 1	8945477	Nucleotide exchange on ARF mediated by yeast Gea1 protein.

Q9LG23	PPR82_ARATH	Pentatricopeptide repeat-containing protein At1g55890, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q05027	TAF9_YEAST	Transcription initiation factor TFIID subunit 9	12446794	The novel SLIK histone acetyltransferase complex functions in the yeast retrograde response pathway.

O42657	YF82_SCHPO	GRIP and coiled-coil domain-containing protein C27D7.02c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P17795	VIRB5_AGRT5	Protein virB5	2233252	Characterization of the virB operon of an Agrobacterium tumefaciens Ti plasmid: nucleotide sequence and protein analysis.

Q5U374	KLH12_DANRE	Kelch-like protein 12	16547521	The KLHL12-cullin-3 ubiquitin ligase negatively regulates the Wnt- beta-catenin pathway by targeting Dishevelled for degradation.

O94913	PCF11_HUMAN	Pre-mRNA cleavage complex 2 protein Pcf11	11060040	Human pre-mRNA cleavage factor II(m) contains homologs of yeast proteins and bridges two other cleavage factors.

O14357	GPI1_SCHPO	N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein gpi1	9046095	The essential Schizosaccharomyces pombe gpi1+ gene complements a bakers' yeast GPI anchoring mutant and is required for efficient cell separation.

Q9UKA1	FBXL5_HUMAN	F-box/LRR-repeat protein 5	19762596	Control of iron homeostasis by an iron-regulated ubiquitin ligase.

P47128	EAF6_YEAST	Chromatin modification-related protein EAF6	15485911	The Yaf9 component of the SWR1 and NuA4 complexes is required for proper gene expression, histone H4 acetylation, and Htz1 replacement near telomeres.

Q14558	KPRA_HUMAN	Phosphoribosyl pyrophosphate synthase-associated protein 1	8611620	Cloning and sequencing of human complementary DNA for the phosphoribosylpyrophosphate synthetase-associated protein 39.

Q8GXV2	CXXS2_ARATH	Thioredoxin-like protein CXXS2	18384502	AtCXXS: atypical members of the Arabidopsis thaliana thioredoxin h family with a remarkably high disulfide isomerase activity.

Q13888	TF2H2_HUMAN	General transcription factor IIH subunit 2	9852112	Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.

Q03001	BPA1_HUMAN	Bullous pemphigoid antigen 1	8575775	Cloning and characterization of the neural isoforms of human dystonin.

P87049	CGP1_SCHPO	G1/S-specific cyclin pas1	10982385	A pcl-like cyclin activates the Res2p-Cdc10p cell cycle 'start' transcriptional factor complex in fission yeast.

Q9M7Q4	AI5L5_ARATH	ABSCISIC ACID-INSENSITIVE 5-like protein 5	16463099	Transcriptional regulation of ABI3- and ABA-responsive genes including RD29B and RD29A in seeds, germinating embryos, and seedlings of Arabidopsis.

P25453	DMC1_YEAST	Meiotic recombination protein DMC1	1581960	DMC1: a meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progression.

Q8TCU4	ALMS1_HUMAN	Alstrom syndrome protein 1	15855349	Subcellular localization of ALMS1 supports involvement of centrosome and basal body dysfunction in the pathogenesis of obesity, insulin resistance, and type 2 diabetes.

Q91WA1	TIPIN_MOUSE	TIMELESS-interacting protein	12875843	Tipin, a novel timeless-interacting protein, is developmentally co- expressed with timeless and disrupts its self-association.

O13978	MUG66_SCHPO	Meiotically up-regulated gene 66 protein	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

Q8K4S3	S45A1_RAT	Proton-associated sugar transporter A	12417639	Past-A, a novel proton-associated sugar transporter, regulates glucose homeostasis in the brain.

P41810	COPB_YEAST	Coatomer subunit beta	7929113	Yeast beta- and beta'-coat proteins (COP). Two coatomer subunits essential for endoplasmic reticulum-to-Golgi protein traffic.

Q5TAT6	CODA1_HUMAN	Collagen alpha-1(XIII) chain	2459707	Gene structure for the alpha 1 chain of a human short-chain collagen (type XIII) with alternatively spliced transcripts and translation termination codon at the 5' end of the last exon.

O74995	TFH47_SCHPO	TFIIH basal transcription factor complex p47 subunit	10077189	Analysis of TFIIH subunit through isolation of the gene from Schizosaccharomyces pombe corresponding to that of Saccharomyces cerevisiae SSL1, reveals the presence of conserved structural motifs.

O77237	PELI_DROME	Protein pellino	10330490	Oligomerisation of Tube and Pelle leads to nuclear localisation of dorsal.

P19524	MYO2_YEAST	Myosin-2	12391144	Complex formation with Ypt11p, a rab-type small GTPase, is essential to facilitate the function of Myo2p, a class V myosin, in mitochondrial distribution in Saccharomyces cerevisiae.

Q99698	LYST_HUMAN	Lysosomal-trafficking regulator	11984006	The Chediak-Higashi protein interacts with SNARE complex and signal transduction proteins.

P43565	RIM15_YEAST	Serine/threonine-protein kinase RIM15	9111339	Stimulation of yeast meiotic gene expression by the glucose- repressible protein kinase Rim15p.

Q7TNH6	NPHP3_MOUSE	Nephrocystin-3	12872122	Mutations in a novel gene, NPHP3, cause adolescent nephronophthisis, tapeto-retinal degeneration and hepatic fibrosis.

Q14444	CAPR1_HUMAN	Caprin-1	7657653	Identification and characterization of a novel protein (p137) which transcytoses bidirectionally in Caco-2 cells.

P97479	MYO7A_MOUSE	Myosin-VIIa	7870172	A type VII myosin encoded by the mouse deafness gene shaker-1.

O42659	APC14_SCHPO	Anaphase-promoting complex subunit 14	12477395	Proteomics analysis identifies new components of the fission and budding yeast anaphase-promoting complexes.

P41499	PTN11_RAT	Tyrosine-protein phosphatase non-receptor type 11	7512964	RNA splicing regulates the activity of a SH2 domain-containing protein tyrosine phosphatase.

P28061	PSB_THEAC	Proteasome subunit beta	7725107	Proteasome from Thermoplasma acidophilum: a threonine protease.

P53668	LIMK1_MOUSE	LIM domain kinase 1	16204183	The ubiquitin ligase Rnf6 regulates local LIM kinase 1 levels in axonal growth cones.

P49407	ARRB1_HUMAN	Beta-arrestin-1	9924018	Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes.

Q99638	RAD9A_HUMAN	Cell cycle checkpoint control protein RAD9A	14500360	Expression of mammalian paralogues of HRAD9 and Mrad9 checkpoint control genes in normal and cancerous testicular tissue.

Q7TSA3	BTLA_MOUSE	B- and T-lymphocyte attenuator	12796776	BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1.

Q9FLW0	Y5241_ARATH	Probable receptor-like protein kinase At5g24010	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q06135	GAS2_YEAST	1,3-beta-glucanosyltransferase GAS2	17189486	GAS2 and GAS4, a pair of developmentally regulated genes required for spore wall assembly in Saccharomyces cerevisiae.

Q39219	AOX1A_ARATH	Alternative oxidase 1a, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q93009	UBP7_HUMAN	Ubiquitin carboxyl-terminal hydrolase 7	16474402	Molecular recognition of p53 and MDM2 by USP7/HAUSP.

P26992	CNTFR_HUMAN	Ciliary neurotrophic factor receptor subunit alpha	12707266	Solution structure of the C-terminal domain of the ciliary neurotrophic factor (CNTF) receptor and ligand free associations among components of the CNTF receptor complex.

Q9NZL4	HPBP1_HUMAN	Hsp70-binding protein 1	9830037	Inhibition of Hsp70 ATPase activity and protein renaturation by a novel Hsp70-binding protein.

P40959	MVP1_YEAST	Sorting nexin MVP1	7862158	The Saccharomyces cerevisiae MVP1 gene interacts with VPS1 and is required for vacuolar protein sorting.

P01233	CGHB_HUMAN	Choriogonadotropin subunit beta	6690982	Evolution of the genes for the beta subunits of human chorionic gonadotropin and luteinizing hormone.

Q13950	RUNX2_HUMAN	Runt-related transcription factor 2	11965546	MOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2.

P42167	LAP2B_HUMAN	Lamina-associated polypeptide 2, isoforms beta/gamma	8530026	Structure and mapping of the human thymopoietin (TMPO) gene and relationship of human TMPO beta to rat lamin-associated polypeptide 2.

P39053	DYN1_MOUSE	Dynamin-1	11956154	The endocytosis-linked protein dynamin associates with caveolin-1 and is tyrosine phosphorylated in response to the activation of a noninternalizing epidermal growth factor receptor mutant.

Q96EL2	RT24_HUMAN	28S ribosomal protein S24, mitochondrial	10938081	A proteomics approach to the identification of mammalian mitochondrial small subunit ribosomal proteins.

P29547	EF1G1_YEAST	Elongation factor 1-gamma 1	12824466	A homologue of elongation factor 1 gamma regulates methionine sulfoxide reductase A gene expression in Saccharomyces cerevisiae.

P14242	PMS1_YEAST	DNA mismatch repair protein PMS1	11717305	Differential ATP binding and intrinsic ATP hydrolysis by amino- terminal domains of the yeast Mlh1 and Pms1 proteins.

B7ZSG3	WT1A_XENLA	Wilms tumor protein homolog A	16818449	The Notch-effector HRT1 gene plays a role in glomerular development and patterning of the Xenopus pronephros anlagen.

P15303	SEC23_YEAST	Protein transport protein SEC23	8451644	Requirement for a GTPase-activating protein in vesicle budding from the endoplasmic reticulum.

O13788	SSR1_SCHPO	SWI/SNF and RSC complexes subunit ssr1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P07654	PSTA_ECOLI	Phosphate transport system permease protein pstA	11867724	Rapid topology mapping of Escherichia coli inner-membrane proteins by prediction and PhoA/GFP fusion analysis.

Q64368	DAZL_MOUSE	Deleted in azoospermia-like	9288969	The mouse Dazla gene encodes a cytoplasmic protein essential for gametogenesis.

Q39162	TGA4_ARATH	Transcription factor TGA4	9159183	Arabidopsis thaliana ethylene-responsive element binding protein (AtEBP), an ethylene-inducible, GCC box DNA-binding protein interacts with an ocs element binding protein.

P53168	DUO1_YEAST	DASH complex subunit DUO1	9817759	Saccharomyces cerevisiae Duo1p and Dam1p, novel proteins involved in mitotic spindle function.

Q9SUS5	RHA1B_ARATH	E3 ubiquitin-protein ligase RHA1B	15644464	Functional analysis of the RING-type ubiquitin ligase family of Arabidopsis.

P20594	ANPRB_HUMAN	Atrial natriuretic peptide receptor 2	1672777	Selective activation of the B natriuretic peptide receptor by C-type natriuretic peptide (CNP).

P36224	JNM1_YEAST	Nuclear migration protein JNM1	16291862	Arp10p is a pointed-end-associated component of yeast dynactin.

Q12230	LSP1_YEAST	Sphingolipid long chain base-responsive protein LSP1	14562095	Global analysis of protein localization in budding yeast.

Q9C0Y5	PDR1_SCHPO	ATP-binding cassette transporter pdr1	16849797	A survey of all 11 ABC transporters in fission yeast: two novel ABC transporters are required for red pigment accumulation in a Schizosaccharomyces pombe adenine biosynthetic mutant.

Q01214	MTF1_RHIRA	Putative transcription factor MTF1	8728109	Cloning and sequence analysis of a putative transcription factor (MTF1) gene from Mucor circinelloides.

P15923	TFE2_HUMAN	Transcription factor E2-alpha	15044608	Increased expression of the FIGLA transcription factor is associated with primordial follicle formation in the human fetal ovary.

Q9JKT9	TR107_RAT	Taste receptor type 2 member 107	10761934	A novel family of mammalian taste receptors.

O43083	HPC2_SCHPO	Histone promoter control protein 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q13190	STX5_HUMAN	Syntaxin-5	9188044	Cloning and identification of human syntaxin 5 as a synaptobrevin/VAMP binding protein.

P55055	NR1H2_HUMAN	Oxysterols receptor LXR-beta	7926814	NER, a new member of the gene family encoding the human steroid hormone nuclear receptor.

Q80Y84	KDM5B_MOUSE	Lysine-specific demethylase 5B	17320160	The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases.

Q9C0W5	YHLE_SCHPO	Uncharacterized mitochondrial membrane protein C800.14c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9XFD1	NCBP2_ARATH	Nuclear cap-binding protein subunit 2	11525733	An mRNA cap binding protein, ABH1, modulates early abscisic acid signal transduction in Arabidopsis.

Q9UNS2	CSN3_HUMAN	COP9 signalosome complex subunit 3	11418127	CSN3 interacts with IKKgamma and inhibits TNF- but not IL-1-induced NF-kappaB activation.

Q9S7Z3	PCS1_ARATH	Glutathione gamma-glutamylcysteinyltransferase 1	17253989	Function of phytochelatin synthase in catabolism of glutathione- conjugates.

P99026	PSB4_MOUSE	Proteasome subunit beta type-4	12874245	The proteasome as a lipopolysaccharide-binding protein in macrophages: differential effects of proteasome inhibition on lipopolysaccharide-induced signaling events.

O15228	GNPAT_HUMAN	Dihydroxyacetone phosphate acyltransferase	9459311	Ether lipid biosynthesis: isolation and molecular characterization of human dihydroxyacetonephosphate acyltransferase.

Q9JHI7	EXOS9_MOUSE	Exosome complex exonuclease RRP45	10708524	Structure and localization of mouse Pmscl1 and Pmscl2 genes.

Q8BVN9	MAEL_MOUSE	Protein maelstrom homolog	16787967	Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway?

Q9UHI7	S23A1_HUMAN	Solute carrier family 23 member 1	10631088	Human vitamin C (L-ascorbic acid) transporter SVCT1.

Q54QT8	CBPG_DICDI	Calcium-binding protein G	14706075	Identification and characterization of novel calcium-binding proteins of Dictyostelium and their spatial expression patterns during development.

Q09847	NU146_SCHPO	Nucleoporin nup146	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P59016	VP33B_MOUSE	Vacuolar protein sorting-associated protein 33B	20190753	Mutations in VIPAR cause an arthrogryposis, renal dysfunction and cholestasis syndrome phenotype with defects in epithelial polarization.

P0AGL7	RSME_ECOLI	Ribosomal RNA small subunit methyltransferase E	16431987	Identification and characterization of RsmE, the founding member of a new RNA base methyltransferase family.

P78549	NTHL1_HUMAN	Endonuclease III-like protein 1	12531031	Differential intracellular localization of the human and mouse endonuclease III homologs and analysis of the sorting signals.

O60264	SMCA5_HUMAN	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5	15543136	The Williams syndrome transcription factor interacts with PCNA to target chromatin remodelling by ISWI to replication foci.

O73689	ZIC1_XENLA	Zinc finger protein ZIC 1	17409353	The activity of Pax3 and Zic1 regulates three distinct cell fates at the neural plate border.

Q9VTN0	GR68A_DROME	Gustatory receptor 68a	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

P32487	LYP1_YEAST	Lysine-specific permease	10654085	Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae.

Q9W698	1A1L1_TAKRU	1-aminocyclopropane-1-carboxylate synthase-like protein 1	11470512	The human cDNA for a homologue of the plant enzyme 1- aminocyclopropane-1-carboxylate synthase encodes a protein lacking that activity.

Q10243	VPS26_SCHPO	Vacuolar protein sorting-associated protein 26	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q99615	DNJC7_HUMAN	DnaJ homolog subfamily C member 7	12853476	Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system.

O43559	FRS3_HUMAN	Fibroblast growth factor receptor substrate 3	9660748	Novel recognition motif on fibroblast growth factor receptor mediates direct association and activation of SNT adapter proteins.

P92948	CDC5L_ARATH	Cell division cycle 5-like protein	19629177	Two Prp19-like U-box proteins in the MOS4-associated complex play redundant roles in plant innate immunity.

P76038	PUUD_ECOLI	Gamma-glutamyl-gamma-aminobutyrate hydrolase	15590624	A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.

Q8CJF7	ELYS_MOUSE	Protein ELYS	11952839	Identification of a novel transcription factor, ELYS, expressed predominantly in mouse foetal haematopoietic tissues.

P53734	DBP6_YEAST	ATP-dependent RNA helicase DBP6	15126390	The putative RNA helicase Dbp6p functionally interacts with Rpl3p, Nop8p and the novel trans-acting Factor Rsa3p during biogenesis of 60S ribosomal subunits in Saccharomyces cerevisiae.

Q9P7Z8	YOUD_SCHPO	Uncharacterized protein C26H8.13c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q15555	MARE2_HUMAN	Microtubule-associated protein RP/EB family member 2	9233623	RP1, a new member of the adenomatous polyposis coli-binding EB1-like gene family, is differentially expressed in activated T cells.

Q9UH92	MLX_HUMAN	Max-like protein X	10918583	Mlx, a new Max-like bHLHZip family member: the center stage of a novel transcription factors regulatory pathway?

O43781	DYRK3_HUMAN	Dual specificity tyrosine-phosphorylation-regulated kinase 3	9748265	Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases.

P42286	THR_DROME	Protein three rows	11581162	Drosophila separase is required for sister chromatid separation and binds to PIM and THR.

P25332	RBSK_YEAST	Probable ribokinase	14562095	Global analysis of protein localization in budding yeast.

P82933	RT09_HUMAN	28S ribosomal protein S9, mitochondrial	11279123	The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present.

Q6B516	SPHKB_DICDI	Sphingosine kinase B	15643073	Sphingosine kinase regulates the sensitivity of Dictyostelium discoideum cells to the anticancer drug cisplatin.

Q680Q4	SIZ1_ARATH	E3 SUMO-protein ligase SIZ1	18502747	The PHD domain of plant PIAS proteins mediates sumoylation of bromodomain GTE proteins.

Q91713	CHRD_XENLA	Chordin	8001117	Xenopus chordin: a novel dorsalizing factor activated by organizer- specific homeobox genes.

Q8N6Y0	USBP1_HUMAN	Usher syndrome type-1C protein-binding protein 1	11311560	Interaction of MCC2, a novel homologue of MCC tumor suppressor, with PDZ-domain protein AIE-75.

Q9UBV4	WNT16_HUMAN	Protein Wnt-16	10500199	Oncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WNT gene in pre-B acute lymphoblastoid leukemia.

O95070	YIF1A_HUMAN	Protein YIF1A	15308636	Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46.

P35900	K1C20_HUMAN	Keratin, type I cytoskeletal 20	10973561	An immunohistological study of cytokeratin 20 in human and mammalian oral epithelium.

Q7Y0W3	EHD1_ORYSI	Two-component response regulator EHD1	15078816	Ehd1, a B-type response regulator in rice, confers short-day promotion of flowering and controls FT-like gene expression independently of Hd1.

Q9JHS1	EPAS1_RAT	Endothelial PAS domain-containing protein 1	11237857	Perivenous expression of the mRNA of the three hypoxia-inducible factor a-subunits HIF-1a, HIF2a and HIF3a in rat liver.

P10398	ARAF_HUMAN	Serine/threonine-protein kinase A-Raf	3029685	The complete coding sequence of the human A-raf-1 oncogene and transforming activity of a human A-raf carrying retrovirus.

Q9JM95	SIA7F_MOUSE	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6	10702226	Molecular cloning and expression of mouse GD1alpha/GT1aalpha/GQ1balpha synthase (ST6GalNAc VI) gene.

Q969H0	FBXW7_HUMAN	F-box/WD repeat-containing protein 7	12354302	SEL-10 interacts with presenilin 1, facilitates its ubiquitination, and alters A-beta peptide production.

Q9Y815	RSV2_SCHPO	Zinc finger protein rsv2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9R0B7	ZN346_MOUSE	Zinc finger protein 346	10488071	JAZ requires the double-stranded RNA-binding zinc finger motifs for nuclear localization.

Q9Z0H4	CELF2_MOUSE	CUGBP Elav-like family member 2	15830352	Dynamic balance between activation and repression regulates pre-mRNA alternative splicing during heart development.

O08901	BUB1_MOUSE	Mitotic checkpoint serine/threonine-protein kinase BUB1	17925231	Bub1 maintains centromeric cohesion by activation of the spindle checkpoint.

Q9UM54	MYO6_HUMAN	Myosin-VI	9259267	Characterization of unconventional MYO6, the human homologue of the gene responsible for deafness in Snell's waltzer mice.

O13023	HHEX_XENLA	Hematopoietically-expressed homeobox protein hhex	12464432	Xhex-expressing endodermal tissues are essential for anterior patterning in Xenopus.

P02599	CALM_DICDI	Calmodulin	6243626	Isolation and properties of calmodulin from Dictyostelium discoideum.

Q8K4V4	SNX27_RAT	Sorting nexin-27	12740601	A developmentally regulated and psychostimulant-inducible novel rat gene mrt1 encoding PDZ-PX proteins isolated in the neocortex.

P53969	SAM50_YEAST	Sorting assembly machinery 50 kDa subunit	14570913	An essential role of Sam50 in the protein sorting and assembly machinery of the mitochondrial outer membrane.

P53140	RMD9_YEAST	Protein RMD9, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

O74865	YQ9F_SCHPO	Uncharacterized WD repeat-containing protein C18.15	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8N5M1	ATPF2_HUMAN	ATP synthase mitochondrial F1 complex assembly factor 2	14757859	Respiratory chain complex V deficiency due to a mutation in the assembly gene ATP12.

P41229	KDM5C_HUMAN	Lysine-specific demethylase 5C	17320160	The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases.

Q9C9C9	SOT18_ARATH	Sulfotransferase 18	15358770	Desulfoglucosinolate sulfotransferases from Arabidopsis thaliana catalyze the final step in the biosynthesis of the glucosinolate core structure.

P50991	TCPD_HUMAN	T-complex protein 1 subunit delta	9819444	Maturation of human cyclin E requires the function of eukaryotic chaperonin CCT.

Q09892	HOG1_SCHPO	Mitogen-activated protein kinase sty1	7501024	Cell-cycle control linked to extracellular environment by MAP kinase pathway in fission yeast.

Q9JLN9	MTOR_MOUSE	Serine/threonine-protein kinase mTOR	15467718	Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive.

P47041	BIT61_YEAST	Target of rapamycin complex 2 subunit BIT61	14736892	TOR complex 1 includes a novel component, Tco89p (YPL180w), and cooperates with Ssd1p to maintain cellular integrity in Saccharomyces cerevisiae.

P53146	USE1_YEAST	Protein transport protein USE1	12853481	Use1p is a yeast SNARE protein required for retrograde traffic to the ER.

Q9SRK7	AZG1_ARATH	Adenine/guanine permease AZG1	19121308	AtAzg1 and AtAzg2 comprise a novel family of purine transporters in Arabidopsis.

Q93WD2	CB29_CHLRE	Chlorophyll a-b binding protein CP29	15094049	The transit peptide of CP29 thylakoid protein in Chlamydomonas reinhardtii is not removed but undergoes acetylation and phosphorylation.

Q62193	RFA2_MOUSE	Replication protein A 32 kDa subunit	17141802	Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factors.

Q91ZY6	HOP2_RAT	Homologous-pairing protein 2 homolog	11739747	Identification and characterization of a tissue-specific coactivator, GT198, that interacts with the DNA-binding domains of nuclear receptors.

P20425	KCY_DICDI	Cytidylate kinase	8703943	Crystal structure of the complex of UMP/CMP kinase from Dictyostelium discoideum and the bisubstrate inhibitor P1-(5'-adenosyl) P5-(5'- uridyl) pentaphosphate (UP5A) and Mg2+ at 2.2-A: implications for water-mediated specificity.

Q9XTQ5	GOB1_CAEEL	Trehalose-phosphatase	16197937	The C. elegans lethal gut-obstructed gob-1 gene is trehalose-6- phosphate phosphatase.

Q8BLA8	TRPA1_MOUSE	Transient receptor potential cation channel subfamily A member 1	15843607	Nociceptor and hair cell transducer properties of TRPA1, a channel for pain and hearing.

P04437	TVA2_HUMAN	T-cell receptor alpha chain V region CTL-L17	2426193	The complete primary structure of the T-cell receptor genes from an alloreactive cytotoxic human T-lymphocyte clone.

Q9UUG0	FAS1_SCHPO	Fatty acid synthase subunit beta	9693066	Cloning of the fatty acid synthetase beta subunit from fission yeast, coexpression with the alpha subunit, and purification of the intact multifunctional enzyme complex.

P11709	BIK1_YEAST	Nuclear fusion protein BIK1	2277073	BIK1, a protein required for microtubule function during mating and mitosis in Saccharomyces cerevisiae, colocalizes with tubulin.

O00221	IKBE_HUMAN	NF-kappa-B inhibitor epsilon	9135156	IkappaB epsilon, a novel member of the IkappaB family, controls RelA and cRel NF-kappaB activity.

P81450	ATP18_YEAST	ATP synthase subunit J, mitochondrial	9867807	ATP synthase of yeast mitochondria. Isolation of subunit j and disruption of the ATP18 gene.

P38250	IST2_YEAST	Increased sodium tolerance protein 2	15701790	Interaction among Btn1p, Btn2p, and Ist2p reveals potential interplay among the vacuole, amino acid levels, and ion homeostasis in the yeast Saccharomyces cerevisiae.

Q8K4V2	B3A4_RAT	Anion exchange protein 4	12225984	AE4 is a DIDS-sensitive Cl(-)/HCO(-)(3) exchanger in the basolateral membrane of the renal CCD and the SMG duct.

Q9PVX8	STA31_XENLA	Signal transducer and activator of transcription 3.1	10642787	Activation of Stat3 by cytokine receptor gp130 ventralizes Xenopus embryos independent of BMP-4.

P22083	FUT4_HUMAN	Alpha-(1,3)-fucosyltransferase	1716630	Molecular cloning of a human fucosyltransferase gene that determines expression of the Lewis x and VIM-2 epitopes but not ELAM-1-dependent cell adhesion.

Q99JD4	CLAP2_RAT	CLIP-associating protein 2	11290329	Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts.

O75379	VAMP4_HUMAN	Vesicle-associated membrane protein 4	9553086	Seven novel mammalian SNARE proteins localize to distinct membrane compartments.

P60752	MSBA_ECOLI	Lipid A export ATP-binding/permease protein msbA	11278265	An Escherichia coli mutant defective in lipid export.

Q76LX8	ATS13_HUMAN	A disintegrin and metalloproteinase with thrombospondin motifs 13	11535495	Purification of human von Willebrand factor-cleaving protease and its identification as a new member of the metalloproteinase family.

P36941	TNR3_HUMAN	Tumor necrosis factor receptor superfamily member 3	8171323	A lymphotoxin-beta-specific receptor.

P28646	SSR1_RAT	Somatostatin receptor type 1	1400442	Cloning and expression of a rat somatostatin receptor enriched in brain.

O13790	CUL1_SCHPO	Cullin-1	9990507	Two F-box/WD-repeat proteins Pop1 and Pop2 form hetero- and homo- complexes together with cullin-1 in fission yeast SCF (Skip-cullin-1- F-box) ubiquitin ligase.

Q9UTH1	TRM13_SCHPO	tRNA guanosine-2'-O-methyltransferase trm13	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P51610	HCFC1_HUMAN	Host cell factor 1	15705566	Zhangfei is a potent and specific inhibitor of the host cell factor- binding transcription factor Luman.

Q9BW30	TPPP3_HUMAN	Tubulin polymerization-promoting protein family member 3	17105200	Tubulin polymerization promoting proteins (TPPPs): members of a new family with distinct structures and functions.

O60504	VINEX_HUMAN	Vinexin	12660241	SAFB2, a new scaffold attachment factor homolog and estrogen receptor corepressor.

Q9Y259	CHKB_HUMAN	Choline/ethanolamine kinase	19915674	Differential role of human choline kinase alpha and beta enzymes in lipid metabolism: implications in cancer onset and treatment.

Q9VIS1	CDGAP_DROME	GTPase-activating protein CdGAPr	17360775	Focal adhesion kinase controls morphogenesis of the Drosophila optic stalk.

Q9HDC9	APMAP_HUMAN	Adipocyte plasma membrane-associated protein	18513186	Localization and characterization of the novel protein encoded by C20orf3.

Q4WQY4	M2DH_ASPFU	Mannitol 2-dehydrogenase	18983992	Polyol-specific long-chain dehydrogenases/reductases of mannitol metabolism in Aspergillus fumigatus: biochemical characterization and pH studies of mannitol 2-dehydrogenase and mannitol-1-phosphate 5- dehydrogenase.

Q54RR8	RDEA_DICDI	Phosphorelay intermediate protein rdeA	17659086	High-throughput analysis of spatio-temporal dynamics in Dictyostelium.

A5YM72	CRNS1_HUMAN	Carnosine synthase 1	20097752	Molecular identification of carnosine synthase as ATP-grasp domain- containing protein 1 (ATPGD1).

O95255	MRP6_HUMAN	Multidrug resistance-associated protein 6	10835642	Mutations in a gene encoding an ABC transporter cause pseudoxanthoma elasticum.

P03180	IL10H_EBVB9	Viral interleukin-10 homolog	15837194	Same structure, different function crystal structure of the Epstein- Barr virus IL-10 bound to the soluble IL-10R1 chain.

Q99MA9	NKX61_MOUSE	Homeobox protein Nkx-6.1	10830170	A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube.

Q9Z0U4	GABR1_RAT	Gamma-aminobutyric acid type B receptor subunit 1	9069281	Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors.

Q9LX93	ATL55_ARATH	E3 ubiquitin-protein ligase RING1	17722694	Identification of 118 Arabidopsis transcription factor and 30 ubiquitin-ligase genes responding to chitin, a plant-defense elicitor.

Q8HZK2	DUOX2_PIG	Dual oxidase 2	10601291	Purification of a novel flavoprotein involved in the thyroid NADPH oxidase. Cloning of the porcine and human cDNAs.

O43688	LPP2_HUMAN	Lipid phosphate phosphohydrolase 2	9607309	Identification of a novel human phosphatidic acid phosphatase type 2 isoform.

Q60974	NCOR1_MOUSE	Nuclear receptor corepressor 1	7566114	Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor.

Q06033	ITIH3_HUMAN	Inter-alpha-trypsin inhibitor heavy chain H3	2465147	Human plasma inter-alpha-trypsin inhibitor is encoded by four genes on three chromosomes.

P32745	SSR3_HUMAN	Somatostatin receptor type 3	1337145	Somatostatin receptors, an expanding gene family: cloning and functional characterization of human SSTR3, a protein coupled to adenylyl cyclase.

P11233	RALA_HUMAN	Ras-related protein Ral-A	19306925	Dual regulation of lysophosphatidic acid (LPA1) receptor signalling by Ral and GRK.

Q9C878	BRN1_ARATH	Protein BEARSKIN1	20197506	SOMBRERO, BEARSKIN1, and BEARSKIN2 regulate root cap maturation in Arabidopsis.

Q86V86	PIM3_HUMAN	Serine/threonine-protein kinase pim-3	17270021	Proto-oncogene, Pim-3 with serine/threonine kinase activity, is aberrantly expressed in human colon cancer cells and can prevent Bad- mediated apoptosis.

Q9UGV2	NDRG3_HUMAN	Protein NDRG3	11936845	Characterization and expression of three novel differentiation- related genes belong to the human NDRG gene family.

P36037	DOA1_YEAST	Protein DOA1	14562095	Global analysis of protein localization in budding yeast.

P39682	PRP39_YEAST	Pre-mRNA-processing factor 39	8196608	Commitment of yeast pre-mRNA to the splicing pathway requires a novel U1 small nuclear ribonucleoprotein polypeptide, Prp39p.

Q9LTS3	CKX3_ARATH	Cytokinin dehydrogenase 3	11154345	Molecular and biochemical characterization of a cytokinin oxidase from maize.

Q9LPS1	HXK3_ARATH	Hexokinase-3	12953116	Enzymes of glycolysis are functionally associated with the mitochondrion in Arabidopsis cells.

P36411	RAB7A_DICDI	Ras-related protein Rab-7A	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P05453	ERF3_YEAST	Eukaryotic peptide chain release factor GTP-binding subunit	7556078	The products of the SUP45 (eRF1) and SUP35 genes interact to mediate translation termination in Saccharomyces cerevisiae.

Q9UIG0	BAZ1B_HUMAN	Tyrosine-protein kinase BAZ1B	16252006	Ligand-induced transrepression by VDR through association of WSTF with acetylated histones.

P07949	RET_HUMAN	Proto-oncogene tyrosine-protein kinase receptor Ret	8114939	Mutations of the RET proto-oncogene in Hirschsprung's disease.

P21957	OPI1_YEAST	Transcriptional repressor OPI1	15192221	Phospholipid metabolism regulated by a transcription factor sensing phosphatidic acid.

Q13023	AKAP6_HUMAN	A-kinase anchor protein 6	10413680	mAKAP: an A-kinase anchoring protein targeted to the nuclear membrane of differentiated myocytes.

Q46925	CSDA_ECOLI	Cysteine sulfinate desulfinase	9278392	Cysteine sulfinate desulfinase, a NIFS-like protein of Escherichia coli with selenocysteine lyase and cysteine desulfurase activities. Gene cloning, purification, and characterization of a novel pyridoxal enzyme.

P54826	GAS1_HUMAN	Growth arrest-specific protein 1	8127893	Structure, function, and chromosome mapping of the growth-suppressing human homologue of the murine gas1 gene.

Q9FUP0	OPR3_ARATH	12-oxophytodienoate reductase 3	11094980	An Arabidopsis gene induced by wounding functionally homologous to flavoprotein oxidoreductases.

Q9P7P1	RPA14_SCHPO	DNA-directed RNA polymerase I subunit rpa14	15647272	The fission yeast protein Ker1p is an ortholog of RNA polymerase I subunit A14 in Saccharomyces cerevisiae and is required for stable association of Rrn3p and RPA21 in RNA polymerase I.

Q6VNB8	WDFY3_MOUSE	WD repeat and FYVE domain-containing protein 3	15342963	Expression profile of mouse BWF1, a protein with a BEACH domain, WD40 domain and FYVE domain.

Q6DUW8	IDL5_ARATH	Protein IDA-LIKE 5	18660431	The EPIP peptide of INFLORESCENCE DEFICIENT IN ABSCISSION is sufficient to induce abscission in arabidopsis through the receptor- like kinases HAESA and HAESA-LIKE2.

P70428	EXT2_MOUSE	Exostosin-2	10639137	The putative tumor suppressors EXT1 and EXT2 form a stable complex that accumulates in the Golgi apparatus and catalyzes the synthesis of heparan sulfate.

Q8RXN0	AB11G_ARATH	ABC transporter G family member 11	17951461	The Arabidopsis DESPERADO/AtWBC11 transporter is required for cutin and wax secretion.

P35582	FOXA1_MOUSE	Hepatocyte nuclear factor 3-alpha	15668254	Compensatory roles of Foxa1 and Foxa2 during lung morphogenesis.

P49454	CENPF_HUMAN	Centromere protein F	7651420	Characterization of a novel 350-kilodalton nuclear phosphoprotein that is specifically involved in mitotic-phase progression.

Q15366	PCBP2_HUMAN	Poly(rC)-binding protein 2	19029303	Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs.

P13468	K10_DROME	DNA-binding protein K10	12553295	Role of the oocyte nucleus in determination of the dorsoventral polarity of Drosophila as revealed by molecular analysis of the K10 gene.

O94454	CSN5_SCHPO	COP9 signalosome complex subunit 5	11854407	Deletion mutants in COP9/signalosome subunits in fission yeast Schizosaccharomyces pombe display distinct phenotypes.

Q9Z2A0	PDPK1_MOUSE	3-phosphoinositide-dependent protein kinase 1	10075713	Primary structure, tissue distribution, and expression of mouse phosphoinositide-dependent protein kinase-1, a protein kinase that phosphorylates and activates protein kinase C zeta.

P97769	CITE1_MOUSE	Cbp/p300-interacting transactivator 1	8901575	msg1, a novel melanocyte-specific gene, encodes a nuclear protein and is associated with pigmentation.

Q9LUD9	GGPP3_ARATH	Geranylgeranyl pyrophosphate synthase 3, chloroplastic	10759500	Five geranylgeranyl diphosphate synthases expressed in different organs are localized into three subcellular compartments in Arabidopsis.

P08709	FA7_HUMAN	Coagulation factor VII	3037537	Nucleotide sequence of the gene coding for human factor VII, a vitamin K-dependent protein participating in blood coagulation.

P37355	MENH_ECOLI	2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase	18284213	Identification and characterization of (1R,6R)-2-succinyl-6-hydroxy- 2,4-cyclohexadiene-1-carboxylate synthase in the menaquinone Biosynthesis of Escherichia coli.

P50895	BCAM_HUMAN	Basal cell adhesion molecule	7777537	The Lutheran blood group glycoprotein, another member of the immunoglobulin superfamily, is widely expressed in human tissues and is developmentally regulated in human liver.

Q5SUE7	ADAD1_MOUSE	Adenosine deaminase domain-containing protein 1	7543294	Distribution of Tenr, an RNA-binding protein, in a lattice-like network within the spermatid nucleus in the mouse.

O43264	ZW10_HUMAN	Centromere/kinetochore protein zw10 homolog	9298984	Conservation of the centromere/kinetochore protein ZW10.

Q9UBC3	DNM3B_HUMAN	DNA (cytosine-5)-methyltransferase 3B	11102980	Genetic variation in ICF syndrome: evidence for genetic heterogeneity.

P08138	TNR16_HUMAN	Tumor necrosis factor receptor superfamily member 16	11244088	The atypical protein kinase C-interacting protein p62 is a scaffold for NF-kappaB activation by nerve growth factor.

P41948	MEP2_YEAST	Ammonium transporter MEP2	9482721	The MEP2 ammonium permease regulates pseudohyphal differentiation in Saccharomyces cerevisiae.

O43062	YGT9_SCHPO	Uncharacterized protein C4C3.09	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P05546	HEP2_HUMAN	Heparin cofactor 2	2647747	Heparin cofactor IIOslo. Mutation of Arg-189 to His decreases the affinity for dermatan sulfate.

Q9NQB0	TF7L2_HUMAN	Transcription factor 7-like 2	9065401	Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma.

P32915	SC61A_YEAST	Protein transport protein SEC61	15831493	Subunits of the translocon interact with components of the oligosaccharyl transferase complex.

Q8TE23	TS1R2_HUMAN	Taste receptor type 1 member 2	11917125	Human receptors for sweet and umami taste.

P25846	MSH1_YEAST	DNA mismatch repair protein MSH1, mitochondrial	7961999	The effect of DNA mismatches on the ATPase activity of MSH1, a protein in yeast mitochondria that recognizes DNA mismatches.

Q16655	MAR1_HUMAN	Melanoma antigen recognized by T-cells 1	15695812	MART-1 is required for the function of the melanosomal matrix protein PMEL17/GP100 and the maturation of melanosomes.

Q12093	MTU1_YEAST	Mitochondrial tRNA-specific 2-thiouridylase 1	15944150	Mutations in MTO2 related to tRNA modification impair mitochondrial gene expression and protein synthesis in the presence of a paromomycin resistance mutation in mitochondrial 15 S rRNA.

P40956	GTS1_YEAST	Protein GTS1	8035831	The GTS1 gene, which contains a Gly-Thr repeat, affects the timing of budding and cell size of the yeast Saccharomyces cerevisiae.

P28290	SSFA2_HUMAN	Sperm-specific antigen 2	1555770	Human cleavage signal-1 protein; cDNA cloning, transcription and immunological analysis.

Q9LY87	RGLG2_ARATH	E3 ubiquitin-protein ligase RGLG2	17586653	Ubiquitin lysine 63 chain forming ligases regulate apical dominance in Arabidopsis.

P50753	TNNT2_RAT	Troponin T, cardiac muscle	2760070	Isolation and characterization of cDNA clones encoding embryonic and adult isoforms of rat cardiac troponin T.

P53974	ARK1_YEAST	Actin-regulating kinase 1	10087264	Novel protein kinases Ark1p and Prk1p associate with and regulate the cortical actin cytoskeleton in budding yeast.

Q6IB77	GLYAT_HUMAN	Glycine N-acyltransferase	7802672	Purification to homogeneity of mitochondrial acyl CoA:glycine N- acyltransferase from human liver.

Q12018	CDC53_YEAST	Cell division control protein 53	8943317	Cdc53p acts in concert with Cdc4p and Cdc34p to control the G1-to-S- phase transition and identifies a conserved family of proteins.

P06730	IF4E_HUMAN	Eukaryotic translation initiation factor 4E	3469651	Amino acid sequence of the mRNA cap-binding protein from human tissues.

Q3E842	YM122_YEAST	Uncharacterized endoplamic reticulum membrane protein YMR122W-A	14562095	Global analysis of protein localization in budding yeast.

Q20618	SRA13_CAEEL	Serpentine receptor class alpha-13	12736202	The C. elegans G-protein-coupled receptor SRA-13 inhibits RAS/MAPK signalling during olfaction and vulval development.

Q9M353	CHX20_ARATH	Cation/H(+) antiporter 20	17337534	Participation of endomembrane cation/H+ exchanger AtCHX20 in osmoregulation of guard cells.

Q06504	NAT3_YEAST	N-terminal acetyltransferase B complex catalytic subunit NAT3	12808144	Mdm20 protein functions with Nat3 protein to acetylate Tpm1 protein and regulate tropomyosin-actin interactions in budding yeast.

P48740	MASP1_HUMAN	Mannan-binding lectin serine protease 1	18596036	Crystal structure of the CUB1-EGF-CUB2 domain of human MASP-1/3 and identification of its interaction sites with mannan-binding lectin and ficolins.

Q12106	YO228_YEAST	Uncharacterized protein YOR228C	16407407	Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins.

Q7XKV4	BGL12_ORYSJ	Beta-glucosidase 12	17196101	Analysis of rice glycosyl hydrolase family 1 and expression of Os4bglu12 beta-glucosidase.

P08581	MET_HUMAN	Hepatocyte growth factor receptor	2819873	Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors.

O65782	C83B1_ARATH	Cytochrome P450 83B1	12970475	CYP83A1 and CYP83B1, two nonredundant cytochrome P450 enzymes metabolizing oximes in the biosynthesis of glucosinolates in Arabidopsis.

Q84M92	ARP4_ARATH	Actin-related protein 4	12609034	Cell cycle-dependent association of Arabidopsis actin-related proteins AtARP4 and AtARP7 with the nucleus.

Q68FI1	L14BA_XENLA	Protein LSM14 homolog B-A	17942399	CPEB interacts with an ovary-specific eIF4E and 4E-T in early Xenopus oocytes.

Q9Y0V6	TIM10_CAEEL	Mitochondrial import inner membrane translocase subunit Tim10	15485840	Defective mitochondrial protein translocation precludes normal Caenorhabditis elegans development.

P12367	KAP2_MOUSE	cAMP-dependent protein kinase type II-alpha regulatory subunit	9852104	Identification of tethering domains for protein kinase A type Ialpha regulatory subunits on sperm fibrous sheath protein FSC1.

P20490	FCERB_MOUSE	High affinity immunoglobulin epsilon receptor subunit beta	2527850	Complete structure of the mouse mast cell receptor for IgE (Fc epsilon RI) and surface expression of chimeric receptors (rat-mouse- human) on transfected cells.

Q95XP4	SEM2A_CAEEL	Semaphorin-2A	12679110	The roles of an ephrin and a semaphorin in patterning cell-cell contacts in C. elegans sensory organ development.

P53088	CTU1_YEAST	Cytoplasmic tRNA 2-thiolation protein 1	17592039	A conserved modified wobble nucleoside (mcm5s2U) in lysyl-tRNA is required for viability in yeast.

Q9H9G7	AGO3_HUMAN	Protein argonaute-3	19167051	Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs.

Q12121	YD211_YEAST	Uncharacterized protein YDL211C	14562095	Global analysis of protein localization in budding yeast.

P41832	BNI1_YEAST	Protein BNI1	10085293	Control of mitotic spindle position by the Saccharomyces cerevisiae formin Bni1p.

A9CPT4	TDRD1_ORYLA	Tudor domain-containing protein 1	18224712	Temporal and spatial localization of three germline-specific proteins in medaka.

Q9UBX8	B4GT6_HUMAN	Beta-1,4-galactosyltransferase 6	9597550	The expanding beta 4-galactosyltransferase gene family: messages from the databanks.

P14854	CX6B1_HUMAN	Cytochrome c oxidase subunit 6B1	2172092	Isolation of cDNAs encoding subunit VIb of cytochrome c oxidase and steady-state levels of coxVIb mRNA in different tissues.

P34697	SODC_CAEEL	Superoxide dismutase [Cu-Zn]	8415630	Aging and resistance to oxidative damage in Caenorhabditis elegans.

Q9LU86	PRXQ_ARATH	Peroxiredoxin Q, chloroplastic	16414959	Tocopherol cyclase (VTE1) localization and vitamin E accumulation in chloroplast plastoglobule lipoprotein particles.

Q8BQP9	R7BP_MOUSE	Regulator of G-protein signaling 7-binding protein	15897264	Palmitoylation regulates plasma membrane-nuclear shuttling of R7BP, a novel membrane anchor for the RGS7 family.

O42839	APC4_SCHPO	Anaphase-promoting complex subunit 4	12477395	Proteomics analysis identifies new components of the fission and budding yeast anaphase-promoting complexes.

Q03818	ATG16_YEAST	Autophagy protein 16	8224160	Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae.

Q99MY0	SPZ1_MOUSE	Spermatogenic leucine zipper protein 1	11165476	Spz1, a novel bHLH-Zip protein, is specifically expressed in testis.

Q7Y0W5	EHD1_ORYSJ	Two-component response regulator EHD1	15078816	Ehd1, a B-type response regulator in rice, confers short-day promotion of flowering and controls FT-like gene expression independently of Hd1.

Q9Y7Y5	RT109_SCHPO	Histone acetyltransferase rtt109	17369611	Regulation of histone H3 lysine 56 acetylation in Schizosaccharomyces pombe.

Q8L649	BB_ARATH	E3 ubiquitin ligase BIG BROTHER	16461280	The E3 ubiquitin ligase BIG BROTHER controls arabidopsis organ size in a dosage-dependent manner.

Q9P7J7	ADA2_SCHPO	Transcriptional adapter 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P39112	DSS1_YEAST	Exoribonuclease II, mitochondrial	9829834	The yeast nuclear gene DSS1, which codes for a putative RNase II, is necessary for the function of the mitochondrial degradosome in processing and turnover of RNA.

P51580	TPMT_HUMAN	Thiopurine S-methyltransferase	8316220	Human thiopurine methyltransferase: molecular cloning and expression of T84 colon carcinoma cell cDNA.

Q13002	GRIK2_HUMAN	Glutamate receptor, ionotropic kainate 2	7536611	Functional expression and pharmacological characterization of the human EAA4 (GluR6) glutamate receptor: a kainate selective channel subunit.

Q9H3D4	P63_HUMAN	Tumor protein 63	10373484	p73 and p63 are homotetramers capable of weak heterotypic interactions with each other but not with p53.

Q93V99	PDF2_ARATH	Homeobox-leucine zipper protein PROTODERMAL FACTOR 2	16778018	Characterization of the class IV homeodomain-leucine zipper gene family in Arabidopsis.

O14757	CHK1_HUMAN	Serine/threonine-protein kinase Chk1	19716789	The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress.

P0C6B3	PTCRA_RAT	Pre T-cell antigen receptor alpha	11169403	Early T cell development can be traced in rat fetal liver.

Q9Y337	KLK5_HUMAN	Kallikrein-5	11054574	Sequencing and expression analysis of the serine protease gene cluster located in chromosome 19q13 region.

P32241	VIPR1_HUMAN	Vasoactive intestinal polypeptide receptor 1	8390245	Cloning and functional expression of a human neuroendocrine vasoactive intestinal peptide receptor.

Q9UPN7	PP6R1_HUMAN	Serine/threonine-protein phosphatase 6 regulatory subunit 1	16769727	Protein phosphatase 6 subunit with conserved Sit4-associated protein domain targets IkappaBepsilon.

P43554	SWP82_YEAST	SWI/SNF global transcription activator complex subunit SWP82	12524530	Structural analysis of the yeast SWI/SNF chromatin remodeling complex.

P75817	RUMB_ECOLI	23S rRNA (uracil-5-)-methyltransferase rumB	12907714	Identifying the methyltransferases for m(5)U747 and m(5)U1939 in 23S rRNA using MALDI mass spectrometry.

Q8WXF0	SRS12_HUMAN	Serine/arginine-rich splicing factor 12	11684676	Serine-arginine (SR) protein-like factors that antagonize authentic SR proteins and regulate alternative splicing.

Q948Y1	C719A_COPJA	(S)-canadine synthase	12732624	Molecular cloning and characterization of CYP719, a methylenedioxy bridge-forming enzyme that belongs to a novel P450 family, from cultured Coptis japonica cells.

Q9V730	EXT1_DROME	Exostosin-1	14645127	Three Drosophila EXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans.

Q91848	SIAM_XENLA	Homeobox protein siamois	11578862	Siamois functions in the early blastula to induce Spemann's organiser.

P62979	RS27A_HUMAN	Ubiquitin-40S ribosomal protein S27a	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

P17454	LBP_RABIT	Lipopolysaccharide-binding protein	2402637	Structure and function of lipopolysaccharide binding protein.

P32121	ARRB2_HUMAN	Beta-arrestin-2	12582207	Desensitization, internalization, and signaling functions of beta- arrestins demonstrated by RNA interference.

P53349	M3K1_MOUSE	Mitogen-activated protein kinase kinase kinase 1	14500727	Subdomain VIII is a specificity-determining region in MEKK1.

Q9VET0	NPF_DROME	Neuropeptide F	12848939	Developmental control of foraging and social behavior by the Drosophila neuropeptide Y-like system.

P76273	RSMF_ECOLI	Ribosomal RNA small subunit methyltransferase F	16678201	YebU is a m5C methyltransferase specific for 16 S rRNA nucleotide 1407.

O65874	MTF1_PEA	MADS-box transcription factor 1	9869431	A MADS box transcription factor of the AP1/AGL9 subfamily is also expressed in the seed coat of pea (Pisum sativum) during development.

P22143	CYAH_MYRVE	Cyanamide hydratase	2034671	Isolation and properties of a nitrile hydratase from the soil fungus Myrothecium verrucaria that is highly specific for the fertilizer cyanamide and cloning of its gene.

Q06187	BTK_HUMAN	Tyrosine-protein kinase BTK	11577348	Direct inhibition of Bruton's tyrosine kinase by IBtk, a Btk-binding protein.

P63146	UBE2B_HUMAN	Ubiquitin-conjugating enzyme E2 B	10908344	The human RAD18 gene product interacts with HHR6A and HHR6B.

P09529	INHBB_HUMAN	Inhibin beta B chain	2575216	Activin B: precursor sequences, genomic structure and in vitro activities.

Q8TE69	CX04A_HUMAN	Protein CXorf40A	15541360	Identification and characterization of a novel gene EOLA1 stimulating ECV304 cell proliferation.

Q9LF50	MEX1_ARATH	Maltose excess protein 1, chloroplastic	12766230	Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.

Q8IZP0	ABI1_HUMAN	Abl interactor 1	9010225	Isolation and characterization of e3B1, an eps8 binding protein that regulates cell growth.

Q5W7F2	AGD3_ARATH	ADP-ribosylation factor GTPase-activating protein AGD3	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

Q6FHJ7	SFRP4_HUMAN	Secreted frizzled-related protein 4	12952927	Secreted frizzled-related protein 4 is a potent tumor-derived phosphaturic agent.

Q12368	SNU23_YEAST	23 kDa U4/U6.U5 small nuclear ribonucleoprotein component	10377396	Purification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins.

P31539	HS104_YEAST	Heat shock protein 104	2188365	HSP104 required for induced thermotolerance.

Q20636	GBB2_CAEEL	Guanine nucleotide-binding protein subunit beta-2	11333232	The G protein beta subunit gpb-2 in Caenorhabditis elegans regulates the G(o)alpha-G(q)alpha signaling network through interactions with the regulator of G protein signaling proteins egl-10 and eat-16.

P39517	DHH1_YEAST	ATP-dependent RNA helicase DHH1	12730603	Decapping and decay of messenger RNA occur in cytoplasmic processing bodies.

Q6PCX7	RGMA_MOUSE	Repulsive guidance molecule A	14749425	Repulsive guidance molecule (RGM) gene function is required for neural tube closure but not retinal topography in the mouse visual system.

Q9UP83	COG5_HUMAN	Conserved oligomeric Golgi complex subunit 5	9792665	Purification and characterization of a novel 13 S hetero-oligomeric protein complex that stimulates in vitro Golgi transport.

Q9Z1J1	TF7L1_MOUSE	Transcription factor 7-like 1	9488439	Two members of the Tcf family implicated in Wnt/b-catenin signaling during embryogenesis in the mouse.

O49629	PAP2_ARATH	Probable plastid-lipid-associated protein 2, chloroplastic	16414959	Tocopherol cyclase (VTE1) localization and vitamin E accumulation in chloroplast plastoglobule lipoprotein particles.

O08785	CLOCK_MOUSE	Circadian locomoter output cycles protein kaput	12897057	BMAL1-dependent circadian oscillation of nuclear CLOCK: posttranslational events induced by dimerization of transcriptional activators of the mammalian clock system.

P53068	APC10_YEAST	Anaphase-promoting complex subunit DOC1	12402045	The Doc1 subunit is a processivity factor for the anaphase-promoting complex.

Q9EPK5	WWTR1_MOUSE	WW domain-containing transcription regulator protein 1	11118213	TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins.

P47147	YMR1_YEAST	Phosphoinositide 3-phosphatase	14562095	Global analysis of protein localization in budding yeast.

P06400	RB_HUMAN	Retinoblastoma-associated protein	11571652	The de-ubiquitinating enzyme Unp interacts with the retinoblastoma protein.

P83254	DISB_VIPLE	Disintegrin lebein-1-beta	11343790	Amino acid structure and characterization of a heterodimeric disintegrin from Vipera lebetina venom.

P51589	CP2J2_HUMAN	Cytochrome P450 2J2	11901223	Cloning of CYP2J2 gene and identification of functional polymorphisms.

Q08961	RKM1_YEAST	Ribosomal N-lysine methyltransferase 1	16096273	A novel SET domain methyltransferase modifies ribosomal protein Rpl23ab in yeast.

Q99PG0	AAAD_MOUSE	Arylacetamide deacetylase	19654421	Arylacetamide deacetylase attenuates fatty-acid-induced triacylglycerol accumulation in rat hepatoma cells.

P0A9A6	FTSZ_ECOLI	Cell division protein ftsZ	1528268	The essential bacterial cell-division protein FtsZ is a GTPase.

Q9P6K6	ERV14_SCHPO	ER-derived vesicles protein erv14	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9ZR72	AB1B_ARATH	ABC transporter B family member 1	15908594	Two homologous ATP-binding cassette transporter proteins, AtMDR1 and AtPGP1, regulate Arabidopsis photomorphogenesis and root development by mediating polar auxin transport.

Q9M0X8	BH114_ARATH	Transcription factor bHLH114	16581911	Transcriptional and posttranscriptional regulation of transcription factor expression in Arabidopsis roots.

O54912	KCNK3_RAT	Potassium channel subfamily K member 3	9437008	An open rectifier potassium channel with two pore domains in tandem cloned from rat cerebellum.

Q62862	MP2K5_RAT	Dual specificity mitogen-activated protein kinase kinase 5	7499418	Isolation of MEK5 and differential expression of alternatively spliced forms.

P31939	PUR9_HUMAN	Bifunctional purine biosynthesis protein PURH	14756553	Structural insights into the human and avian IMP cyclohydrolase mechanism via crystal structures with the bound XMP inhibitor.

Q07782	S13A1_RAT	Solute carrier family 13 member 1	7690140	Expression cloning of rat renal Na+/SO4(2-) cotransport.

Q92968	PEX13_HUMAN	Peroxisomal membrane protein PEX13	10704444	PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis.

P21583	SCF_HUMAN	Kit ligand	2208279	Primary structure and functional expression of rat and human stem cell factor DNAs.

Q54S38	RCL1_DICDI	Probable RNA 3'-terminal phosphate cyclase-like protein	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q03571	CPB1_CAEEL	Cytoplasmic polyadenylation element-binding protein 1	11040214	CPEB proteins control two key steps in spermatogenesis in C. elegans.

Q9LME4	P2C09_ARATH	Probable protein phosphatase 2C 9	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

P54623	CNN_DROME	Centrosomin	8582295	The Drosophila homeotic target gene centrosomin (cnn) encodes a novel centrosomal protein with leucine zippers and maps to a genomic region required for midgut morphogenesis.

O81312	GAE3_ARATH	UDP-glucuronate 4-epimerase 3	15247385	The biosynthesis of D-galacturonate in plants. Functional cloning and characterization of a membrane-anchored UDP-D-glucuronate 4-epimerase from Arabidopsis.

P84683	SC40_TITCA	Toxin Tc40	15025998	Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

Q91616	NDF1_XENLA	Neurogenic differentiation factor 1	17008450	Characterization and function of the bHLH-O protein XHes2: insight into the mechanisms controlling retinal cell fate decision.

Q9GN62	PAR4_CAEEL	Serine/threonine-protein kinase par-4	18408008	The Caenorhabditis elegans AMP-activated protein kinase AAK-2 is phosphorylated by LKB1 and is required for resistance to oxidative stress and for normal motility and foraging behavior.

P05165	PCCA_HUMAN	Propionyl-CoA carboxylase alpha chain, mitochondrial	3460076	Isolation of cDNA clones coding for the alpha and beta chains of human propionyl-CoA carboxylase: chromosomal assignments and DNA polymorphisms associated with PCCA and PCCB genes.

P83093	STIM2_MOUSE	Stromal interaction molecule 2	11463338	Identification and characterization of the STIM (stromal interaction molecule) gene family: coding for a novel class of transmembrane proteins.

Q4V8G5	SEP12_RAT	Septin-12	17685441	Sept12 is a component of the mammalian sperm tail annulus.

P34253	KTI12_YEAST	Protein KTI12	15772087	Physical and functional interaction between Elongator and the chromatin-associated Kti12 protein.

Q14240	IF4A2_HUMAN	Eukaryotic initiation factor 4A-II	8521730	Isolation and mapping of the human EIF4A2 gene homologous to the murine protein synthesis initiation factor 4A-II gene Eif4a2.

P36552	HEM6_MOUSE	Coproporphyrinogen-III oxidase, mitochondrial	15482256	Examination of mitochondrial protein targeting of haem synthetic enzymes: in vivo identification of three functional haem-responsive motifs in 5-aminolaevulinate synthase.

Q9UJW2	TINAG_HUMAN	Tubulointerstitial nephritis antigen	10652240	Molecular cloning, expression, and chromosomal localization of a human tubulointerstitial nephritis antigen.

Q8LG50	LPAT2_ARATH	1-acyl-sn-glycerol-3-phosphate acyltransferase 2	15772283	Ubiquitous and endoplasmic reticulum-located lysophosphatidyl acyltransferase, LPAT2, is essential for female but not male gametophyte development in Arabidopsis.

P07251	ATPA_YEAST	ATP synthase subunit alpha, mitochondrial	2876995	Nuclear genes encoding the yeast mitochondrial ATPase complex. Analysis of ATP1 coding the F1-ATPase alpha-subunit and its assembly.

P07866	LTE1_YEAST	Guanine nucleotide exchange factor LTE1	12782684	Ras recruits mitotic exit regulator Lte1 to the bud cortex in budding yeast.

P23894	HTPX_ECOLI	Protease HtpX	1826904	Isolation, characterization, and sequence of an Escherichia coli heat shock gene, htpX.

Q60948	MAD4_MOUSE	Max dimerization protein 4	8521822	Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation.

Q53080	PSA1_RHOER	Proteasome subunit alpha 1	14659753	Crystal structures of the Rhodococcus proteasome with and without its pro-peptides: implications for the role of the pro-peptide in proteasome assembly.

Q9P802	MIS18_SCHPO	Kinetochore protein mis18	15369671	Mis16 and Mis18 are required for CENP-A loading and histone deacetylation at centromeres.

O74984	HSP15_SCHPO	Heat shock protein homolog C338.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P01583	IL1A_HUMAN	Interleukin-1 alpha	3493774	cDNA cloning of IL-1 alpha and IL-1 beta from mRNA of U937 cell line.

Q9Y7N1	YCK3_SCHPO	Uncharacterized protein C1450.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q17TI5	BRX_ARATH	Protein BREVIS RADIX	19037657	BREVIS RADIX is involved in cytokinin-mediated inhibition of lateral root initiation in Arabidopsis.

P62316	SMD2_HUMAN	Small nuclear ribonucleoprotein Sm D2	7527560	cDNA cloning of the Sm proteins D2 and D3 from human small nuclear ribonucleoproteins: evidence for a direct D1-D2 interaction.

Q01460	DIAC_RAT	Di-N-acetylchitobiase	1527079	Cloning and expression of the cDNA sequence encoding the lysosomal glycosidase di-N-acetylchitobiase.

O60678	ANM3_HUMAN	Protein arginine N-methyltransferase 3	9642256	PRMT 3, a type I protein arginine N-methyltransferase that differs from PRMT1 in its oligomerization, subcellular localization, substrate specificity, and regulation.

P84640	CYVD_LEOCM	Cycloviolin-D	10813905	Cycloviolins A-D, anti-HIV macrocyclic peptides from Leonia cymosa.

P62861	RS30_HUMAN	40S ribosomal protein S30	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

P36141	FMP46_YEAST	Putative redox protein FMP46, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q62599	MTA1_RAT	Metastasis-associated protein MTA1	10933808	SH3 binding sites of ZG29p mediate an interaction with amylase and are involved in condensation-sorting in the exocrine rat pancreas.

P29131	FTSN_ECOLI	Cell division protein ftsN	8509333	Cloning and characterization of ftsN, an essential cell division gene in Escherichia coli isolated as a multicopy suppressor of ftsA12(Ts).

O75916	RGS9_HUMAN	Regulator of G-protein signaling 9	9765512	Molecular characterization of human and rat RGS9L, a novel splice variant enriched in dopamine target regions, and chromosomal localization of the RGS9 gene.

Q8NFH3	NUP43_HUMAN	Nucleoporin Nup43	17360435	Cell-cycle-dependent phosphorylation of the nuclear pore Nup107-160 subcomplex.

Q9WVR3	SHIP2_RAT	Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2	10648902	Localization of mRNA for SHIP2, SH2 domain-containing inositol polyphosphate 5-phosphatase, in the brain of developing and mature rats.

P68511	1433F_RAT	14-3-3 protein eta	1649368	Molecular cloning of cDNA to rat 14-3-3 eta chain polypeptide and the neuronal expression of the mRNA in the central nervous system.

Q01532	BLH1_YEAST	Cysteine proteinase 1, mitochondrial	9374524	The cysteine-peptidase bleomycin hydrolase is a member of the galactose regulon in yeast.

Q8L7S9	TRXY2_ARATH	Thioredoxin Y2, chloroplastic	15531707	Characterization of plastidial thioredoxins from Arabidopsis belonging to the new y-type.

Q91813	OTX2A_XENLA	Homeobox protein OTX2-A	12710967	Molecular link in the sequential induction of the Spemann organizer: direct activation of the cerberus gene by Xlim-1, Xotx2, Mix.1, and Siamois, immediately downstream from Nodal and Wnt signaling.

Q9V3Y3	DFP_DROME	Defense protein l(2)34Fc	12032070	The Toll and Imd pathways are the major regulators of the immune response in Drosophila.

Q9LN50	PMTS_ARATH	Probable methyltransferase PMT28	16618929	Mapping the Arabidopsis organelle proteome.

Q60793	KLF4_MOUSE	Krueppel-like factor 4	10431239	Klf4 is a transcription factor required for establishing the barrier function of the skin.

P83322	FAR7_PENMO	FMRFamide-like neuropeptide FLP7	11959015	Seven novel FMRFamide-like neuropeptide sequences from the eyestalk of the giant tiger prawn Penaeus monodon.

P08953	TOLL_DROME	Protein toll	8808632	The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults.

P36955	PEDF_HUMAN	Pigment epithelium-derived factor	11562499	Crystal structure of human PEDF, a potent anti-angiogenic and neurite growth-promoting factor.

O75380	NDUS6_HUMAN	NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

Q9XYT4	ORCH_ORCCA	Orchestin	15099573	Orchestin, a calcium-binding phosphoprotein, is a matrix component of two successive transitory calcified biomineralizations cyclically elaborated by a terrestrial crustacean.

Q04121	NHX1_YEAST	Endosomal/prevacuolar sodium/hydrogen exchanger	9694857	Novel localization of a Na+/H+ exchanger in a late endosomal compartment of yeast. Implications for vacuole biogenesis.

P56546	CTBP2_MOUSE	C-terminal-binding protein 2	14736873	Characterization of four autonomous repression domains in the corepressor receptor interacting protein 140.

P20023	CR2_HUMAN	Complement receptor type 2	2827171	Molecular cloning of the cDNA encoding the Epstein-Barr virus.C3d receptor (complement receptor type 2) of human b lymphocytes.

Q1PFR7	LEC2_ARATH	B3 domain-containing transcription factor LEC2	12244265	Leafy cotyledon mutants of Arabidopsis.

Q9R257	HEBP1_MOUSE	Heme-binding protein 1	10640688	Discovery of a putative heme-binding protein family (SOUL/HBP) by two-tissue suppression subtractive hybridization and database searches.

P48439	OST3_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3	10677492	Studies on the role of the hydrophobic domain of Ost4p in interactions with other subunits of yeast oligosaccharyl transferase.

Q8CG64	FKRP_MOUSE	Fukutin-related protein	12471058	Functional requirements for fukutin-related protein in the Golgi apparatus.

P30777	GPI10_YEAST	GPI mannosyltransferase 3	9576863	Saccharomyces cerevisiae GPI10, the functional homologue of human PIG-B, is required for glycosylphosphatidylinositol-anchor synthesis.

P43246	MSH2_HUMAN	DNA mismatch repair protein Msh2	11429708	HNPCC mutations in the human DNA mismatch repair gene hMLH1 influence assembly of hMutLalpha and hMLH1-hEXO1 complexes.

Q62985	SH2B1_RAT	SH2B adapter protein 1	9343427	Identification of SH2-Bbeta as a substrate of the tyrosine kinase JAK2 involved in growth hormone signaling.

Q39099	XTH4_ARATH	Xyloglucan endotransglucosylase/hydrolase protein 4	8696366	The Arabidopsis XET-related gene family: environmental and hormonal regulation of expression.

P41996	CPG2_CAEEL	Chondroitin proteoglycan-2	17913784	Cortical granule exocytosis in C. elegans is regulated by cell cycle components including separase.

Q9VAY3	MFRN_DROME	Mitoferrin	19453295	Overexpression of Drosophila mitoferrin in l(2)mbn cells results in dysregulation of Fer1HCH expression.

P63041	CPLX1_RAT	Complexin-1	11751907	Rapid and selective binding to the synaptic SNARE complex suggests a modulatory role of complexins in neuroexocytosis.

Q8IN42	TOTZ_DROME	Protein Turandot Z	11409894	A family of Turandot-related genes in the humoral stress response of Drosophila.

Q9YGV1	DERR_XENLA	Derriere protein	12361977	Direct and indirect regulation of derriere, a Xenopus mesoderm- inducing factor, by VegT.

Q9UTK1	COX16_SCHPO	Cytochrome c oxidase assembly protein cox16, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UEU0	VTI1B_HUMAN	Vesicle transport through interaction with t-SNAREs homolog 1B	9446565	A human homolog can functionally replace the yeast vesicle-associated SNARE Vti1p in two vesicle transport pathways.

P23528	COF1_HUMAN	Cofilin-1	16548883	Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection.

Q03154	ACY1_HUMAN	Aminoacylase-1	8394326	Human aminoacylase-1. Cloning, sequence, and expression analysis of a chromosome 3p21 gene inactivated in small cell lung cancer.

Q9P6N2	YKBE_SCHPO	Uncharacterized phosphatase C823.14	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P53923	CTU2_YEAST	Cytoplasmic tRNA 2-thiolation protein 2	18755837	A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae.

Q03426	KIME_HUMAN	Mevalonate kinase	10369261	Mutations in MVK, encoding mevalonate kinase, cause hyperimmunoglobulinaemia D and periodic fever syndrome.

Q06625	GDE_YEAST	Glycogen debranching enzyme	14562095	Global analysis of protein localization in budding yeast.

P41236	IPP2_HUMAN	Protein phosphatase inhibitor 2	8119416	Cloning of the complete coding region for human protein phosphatase inhibitor 2 using the two hybrid system and expression of inhibitor 2 in E. coli.

Q14643	ITPR1_HUMAN	Inositol 1,4,5-trisphosphate receptor type 1	8648241	Induction of inositol 1,4,5 trisphosphate receptor genes by ionizing radiation.

Q7L9L4	MOL1A_HUMAN	Mps one binder kinase activator-like 1A	15067004	Human Mob proteins regulate the NDR1 and NDR2 serine-threonine kinases.

Q9P4R5	CREC_EMENI	Catabolite repression protein creC	11442830	Carbon catabolite repression in Aspergillus nidulans involves deubiquitination.

O15392	BIRC5_HUMAN	Baculoviral IAP repeat-containing protein 5	17956729	Structure of a Survivin-Borealin-INCENP core complex reveals how chromosomal passengers travel together.

P40059	DOT6_YEAST	Transcriptional regulatory protein DOT6	19158363	High-resolution DNA-binding specificity analysis of yeast transcription factors.

P36590	KTHY_SCHPO	Thymidylate kinase	1327149	Functional and structural conservation of Schizosaccharomyces pombe dTMP kinase gene.

P36683	ACON2_ECOLI	Aconitate hydratase 2	10585860	Biochemical and spectroscopic characterization of Escherichia coli aconitases (AcnA and AcnB).

Q9FKA7	ORTH1_ARATH	E3 ubiquitin-protein ligase ORTHRUS 1	18643997	ORTH/VIM proteins that regulate DNA methylation are functional ubiquitin E3 ligases.

Q9HGL5	EFTS_SCHPO	Elongation factor Ts, mitochondrial	15695360	Mitochondrial translation: elongation factor tu is essential in fission yeast and depends on an exchange factor conserved in humans but not in budding yeast.

P62826	RAN_HUMAN	GTP-binding nuclear protein Ran	10400640	The linkage of Kennedy's neuron disease to ARA24, the first identified androgen receptor polyglutamine region-associated coactivator.

A6X8Z5	RHG31_MOUSE	Rho GTPase-activating protein 31	11744688	The activity of the GTPase-activating protein CdGAP is regulated by the endocytic protein intersectin.

O14072	ATC4_SCHPO	Cation-transporting ATPase 4	12058018	The endoplasmic reticulum cation P-type ATPase Cta4p is required for control of cell shape and microtubule dynamics.

Q14964	RB39A_HUMAN	Ras-related protein Rab-39A	9119394	Construction of a transcription map around the gene for ataxia telangiectasia; identification of at least four novel genes.

P97470	PP4C_MOUSE	Serine/threonine-protein phosphatase 4 catalytic subunit	9837938	Protein phosphatase X interacts with c-Rel and stimulates c- Rel/nuclear factor kappaB activity.

Q9WTW1	GRIP2_RAT	Glutamate receptor-interacting protein 2	9768844	Novel anchorage of GluR2/3 to the postsynaptic density by the AMPA receptor-binding protein ABP.

P05067	A4_HUMAN	Amyloid beta A4 protein	8626687	APP-BP1, a novel protein that binds to the carboxyl-terminal region of the amyloid precursor protein.

Q9VN14	CONT_DROME	Contactin	15459097	Drosophila contactin, a homolog of vertebrate contactin, is required for septate junction organization and paracellular barrier function.

P54107	CRIS1_HUMAN	Cysteine-rich secretory protein 1	8838800	Characterization of a human glycoprotein with a potential role in sperm-egg fusion: cDNA cloning, immunohistochemical localization, and chromosomal assignment of the gene (AEGL1).

P24864	CCNE1_HUMAN	G1/S-specific cyclin-E1	9840943	Cyclin E2, a novel human G1 cyclin and activating partner of CDK2 and CDK3, is induced by viral oncoproteins.

Q9SKK0	EBF1_ARATH	EIN3-binding F-box protein 1	14675533	EIN3-dependent regulation of plant ethylene hormone signaling by two Arabidopsis F box proteins: EBF1 and EBF2.

P35446	SPON1_RAT	Spondin-1	14983046	Binding of F-spondin to amyloid-beta precursor protein: a candidate amyloid-beta precursor protein ligand that modulates amyloid-beta precursor protein cleavage.

Q9SKT0	THF1_ARATH	Protein THYLAKOID FORMATION 1, chloroplastic	16582010	The plastid protein THYLAKOID FORMATION1 and the plasma membrane G- protein GPA1 interact in a novel sugar-signaling mechanism in Arabidopsis.

P18203	FKB1A_BOVIN	Peptidyl-prolyl cis-trans isomerase FKBP1A	1701173	The cytosolic-binding protein for the immunosuppressant FK-506 is both a ubiquitous and highly conserved peptidyl-prolyl cis-trans isomerase.

Q8CFN5	MEF2C_MOUSE	Myocyte-specific enhancer factor 2C	9778514	Requirement of the MADS-box transcription factor MEF2C for vascular development.

C0LGW6	ERL1_ARATH	LRR receptor-like serine/threonine-protein kinase ERL1	17652352	Haploinsufficiency after successive loss of signaling reveals a role for ERECTA-family genes in Arabidopsis ovule development.

O43280	TREA_HUMAN	Trehalase	9427547	Molecular cloning, sequencing and expression of cDNA encoding human trehalase.

O43504	HBXIP_HUMAN	Hepatitis B virus X-interacting protein	12773388	HBXIP functions as a cofactor of survivin in apoptosis suppression.

Q86TP1	PRUNE_HUMAN	Protein prune homolog	10602478	Evidence for interaction between human PRUNE and nm23-H1 NDPKinase.

O59811	YJVF_SCHPO	Zinc finger protein C550.15c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

B2GV87	PTPRE_RAT	Receptor-type tyrosine-protein phosphatase epsilon	8579581	Molecular cloning of a novel cytoplasmic protein tyrosine phosphatase PTP epsilon.

Q92879	CELF1_HUMAN	CUGBP Elav-like family member 1	16946708	Interaction of muscleblind, CUG-BP1 and hnRNP H proteins in DM1- associated aberrant IR splicing.

O95750	FGF19_HUMAN	Fibroblast growth factor 19	18829467	C-terminal tail of FGF19 determines its specificity toward Klotho co- receptors.

Q9YHV4	FSTA_DANRE	Follistatin-A	9882485	Follistatin and noggin are excluded from the zebrafish organizer.

P32657	CHD1_YEAST	Chromo domain-containing protein 1	10811623	The chromo domain protein chd1p from budding yeast is an ATP- dependent chromatin-modifying factor.

P32471	EF1B_YEAST	Elongation factor 1-beta	8420802	Cloning and characterization of the elongation factor EF-1 beta homologue of Saccharomyces cerevisiae. EF-1 beta is essential for growth.

Q39258	VATE1_ARATH	V-type proton ATPase subunit E1	15610355	Arabidopsis vacuolar H(+)-ATPase subunit E isoform 1 is required for Golgi organization and vacuole function in embryogenesis.

Q9JLH5	CK5P2_RAT	CDK5 regulatory subunit-associated protein 2	10721722	Cloning of three novel neuronal Cdk5 activator binding proteins.

P29476	NOS1_RAT	Nitric oxide synthase, brain	11867766	Neuronal nitric-oxide synthase localization mediated by a ternary complex with synapsin and CAPON.

Q9Y276	BCS1_HUMAN	Mitochondrial chaperone BCS1	18628306	Characterization of the mitochondrial protein LETM1, which maintains the mitochondrial tubular shapes and interacts with the AAA-ATPase BCS1L.

P36531	RM36_YEAST	54S ribosomal protein L36, mitochondrial	12392552	Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components.

Q9NTG7	SIRT3_HUMAN	NAD-dependent deacetylase sirtuin-3, mitochondrial	16079181	Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins.

P54887	P5CS1_ARATH	Delta-1-pyrroline-5-carboxylate synthase A	7773306	Correlation between the induction of a gene for delta 1-pyrroline-5- carboxylate synthetase and the accumulation of proline in Arabidopsis thaliana under osmotic stress.

Q13330	MTA1_HUMAN	Metastasis-associated protein MTA1	8083195	A novel candidate metastasis-associated gene, mta1, differentially expressed in highly metastatic mammary adenocarcinoma cell lines. cDNA cloning, expression, and protein analyses.

Q94361	GEI17_CAEEL	E3 SUMO-protein ligase gei-17	11922622	Isolation of the interacting molecules with GEX-3 by a novel functional screening.

P40384	REC12_SCHPO	Meiotic recombination protein rec12	12437782	Distinct functions of S. pombe Rec12 (Spo11) protein and Rec12- dependent crossover recombination (chiasmata) in meiosis I; and a requirement for Rec12 in meiosis II.

Q8I659	YPF11_PLAF7	Uncharacterized protein PFB0765w	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

Q91848	SIAM_XENLA	Homeobox protein siamois	9371792	Siamois is required for formation of Spemann's organizer.

P30954	O10J1_HUMAN	Olfactory receptor 10J1	1370859	Expression of members of the putative olfactory receptor gene family in mammalian germ cells.

P49893	WN11B_XENLA	Protein Wnt-11b	10862746	Role of frizzled 7 in the regulation of convergent extension movements during gastrulation in Xenopus laevis.

Q9EP80	PICK1_RAT	PRKCA-binding protein	10027300	Clustering of AMPA receptors by the synaptic PDZ domain-containing protein PICK1.

O15357	SHIP2_HUMAN	Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2	15668240	SH2-containing 5'-inositol phosphatase, SHIP2, regulates cytoskeleton organization and ligand-dependent down-regulation of the epidermal growth factor receptor.

Q80ZD7	AMGO1_RAT	Amphoterin-induced protein 1	12629050	AMIGO, a transmembrane protein implicated in axon tract development, defines a novel protein family with leucine-rich repeats.

P18105	NOD_DROME	Kinesin-like protein Nod	2144792	A kinesin-like protein required for distributive chromosome segregation in Drosophila.

Q02974	KHK_RAT	Ketohexokinase	8471037	Expression of rat liver ketohexokinase in yeast results in fructose intolerance.

Q9Y691	KCMB2_HUMAN	Calcium-activated potassium channel subunit beta-2	10692449	Cloning and functional characterization of novel large conductance calcium-activated potassium channel beta subunits, hKCNMB3 and hKCNMB4.

P06780	RHO1_YEAST	GTP-binding protein RHO1	8195291	Growth site localization of Rho1 small GTP-binding protein and its involvement in bud formation in Saccharomyces cerevisiae.

Q9NZU7	CABP1_HUMAN	Calcium-binding protein 1	11865310	Differential modulation of Ca(v)2.1 channels by calmodulin and Ca2+- binding protein 1.

P01562	IFNA1_HUMAN	Interferon alpha-1/13	4057246	Structural relationship of human interferon alpha genes and pseudogenes.

P56180	TPTE_HUMAN	Putative tyrosine-protein phosphatase TPTE	10598804	A testis-specific gene, TPTE, encodes a putative transmembrane tyrosine phosphatase and maps to the pericentromeric region of human chromosomes 21 and 13, and to chromosomes 15, 22, and Y.

Q9JJK4	PEX3_RAT	Peroxisomal biogenesis factor 3	10848631	The peroxin pex3p initiates membrane assembly in peroxisome biogenesis.

Q64364	CD2A2_MOUSE	Cyclin-dependent kinase inhibitor 2A, isoform 3	12154087	CARF is a novel protein that cooperates with mouse p19ARF (human p14ARF) in activating p53.

C0LGH2	Y1561_ARATH	Probable LRR receptor-like serine/threonine-protein kinase At1g56130	17644812	A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome.

P70396	DLX5_MOUSE	Homeobox protein DLX-5	9415433	Dlx genes encode DNA-binding proteins that are expressed in an overlapping and sequential pattern during basal ganglia differentiation.

Q7XJT7	SSP_ARATH	Probable inactive receptor-like kinase SSP	19286558	Paternal control of embryonic patterning in Arabidopsis thaliana.

P25522	MNME_ECOLI	tRNA modification GTPase mnmE	12730230	The GTPase activity and C-terminal cysteine of the Escherichia coli MnmE protein are essential for its tRNA modifying function.

Q9UPT9	UBP22_HUMAN	Ubiquitin carboxyl-terminal hydrolase 22	16378762	The expression patterns of deubiquitinating enzymes, USP22 and Usp22.

Q9P246	STIM2_HUMAN	Stromal interaction molecule 2	18160041	STIM2 is a feedback regulator that stabilizes basal cytosolic and endoplasmic reticulum Ca2+ levels.

P41410	RAD54_SCHPO	DNA repair protein rhp54	8834792	Isolation of the Schizosaccharomyces pombe RAD54 homologue, rhp54+, a gene involved in the repair of radiation damage and replication fidelity.

Q04429	HLR1_YEAST	Protein HLR1	14562095	Global analysis of protein localization in budding yeast.

P08539	GPA1_YEAST	Guanine nucleotide-binding protein alpha-1 subunit	11394869	Biochemical analysis of yeast G(alpha) mutants that enhance adaptation to pheromone.

Q9P378	GAS1_SCHPO	1,3-beta-glucanosyltransferase gas1	17230583	Mass spectrometric identification of covalently bound cell wall proteins from the fission yeast Schizosaccharomyces pombe.

Q93ZB2	KO1_ARATH	Ent-kaurene oxidase, chloroplastic	9671797	Cloning of the Arabidopsis ent-kaurene oxidase gene GA3.

P13686	PPA5_HUMAN	Tartrate-resistant acid phosphatase type 5	15993892	Crystal structures of recombinant human purple acid phosphatase with and without an inhibitory conformation of the repression loop.

Q5PYH6	DLG1_DANRE	Disks large homolog 1	15660367	Characterization of zebrafish PSD-95 gene family members.

Q13683	ITA7_HUMAN	Integrin alpha-7	9590299	Mutations in the integrin alpha7 gene cause congenital myopathy.

Q16553	LY6E_HUMAN	Lymphocyte antigen 6E	8650192	RIG-E, a human homolog of the murine Ly-6 family, is induced by retinoic acid during the differentiation of acute promyelocytic leukemia cell.

Q16630	CPSF6_HUMAN	Cleavage and polyadenylation specificity factor subunit 6	15169763	Distinct sequence motifs within the 68-kDa subunit of cleavage factor Im mediate RNA binding, protein-protein interactions, and subcellular localization.

P53271	COG2_YEAST	Conserved oligomeric Golgi complex subunit 2	11703943	The Sec34/35 Golgi transport complex is related to the exocyst, defining a family of complexes involved in multiple steps of membrane traffic.

Q9BR01	ST4A1_HUMAN	Sulfotransferase 4A1	10698717	Molecular cloning and expression of novel sulphotransferase-like cDNAs from human and rat brain.

Q99943	PLCA_HUMAN	1-acyl-sn-glycerol-3-phosphate acyltransferase alpha	9212163	Cloning and expression of two human lysophosphatidic acid acyltransferase cDNAs that enhance cytokine-induced signaling responses in cells.

P36060	MCR1_YEAST	NADH-cytochrome b5 reductase 2	16407407	Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins.

P11911	CD79A_MOUSE	B-cell antigen receptor complex-associated protein alpha chain	11514602	Interference with immunoglobulin (Ig)alpha immunoreceptor tyrosine- based activation motif (ITAM) phosphorylation modulates or blocks B cell development, depending on the availability of an Igbeta cytoplasmic tail.

P19018	TRA2_DROME	Transformer-2 sex-determining protein	3144434	The sex-determining gene tra-2 of Drosophila encodes a putative RNA binding protein.

Q9HCK8	CHD8_HUMAN	Chromodomain-helicase-DNA-binding protein 8	16949368	CTCF-dependent chromatin insulator is linked to epigenetic remodeling.

O35817	AKA14_RAT	A-kinase anchor protein 14	9208934	Cloning and characterization of a testis-specific, developmentally regulated A-kinase anchoring protein (TAKAP-80) present on the fibrous sheath of rat sperm.

Q03214	ECM5_YEAST	Protein ECM5	14562095	Global analysis of protein localization in budding yeast.

P16228	CATE_RAT	Cathepsin E	8157122	Age-related changes in activities and localizations of cathepsins D, E, B, and L in the rat brain tissues.

Q9C168	CAT1_NEUCR	Catalase-1	11728803	Molecular and kinetic study of catalase-1, a durable large catalase of Neurospora crassa.

Q9CY34	UB2FA_MOUSE	NEDD8-conjugating enzyme UBE2F	19250909	E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification.

Q86VF7	NRAP_HUMAN	Nebulin-related-anchoring protein	9339382	Mapping of the gene (NRAP) encoding N-RAP in the mouse and human genomes.

P33755	NPL4_YEAST	Nuclear protein localization protein 4	11598205	The conserved npl4 protein complex mediates proteasome-dependent membrane-bound transcription factor activation.

Q12429	YL143_YEAST	Putative ribonuclease YLR143W	14562095	Global analysis of protein localization in budding yeast.

P40554	URM1_YEAST	Ubiquitin-related modifier 1	18260097	Crystal structure of the dimeric Urm1 from the yeast Saccharomyces cerevisiae.

Q9M548	DRM2_ARATH	DNA (cytosine-5)-methyltransferase DRM2	12151602	Locus-specific control of asymmetric and CpNpG methylation by the DRM and CMT3 methyltransferase genes.

P10760	SAHH_RAT	Adenosylhomocysteinase	11741948	Inhibition of S-adenosylhomocysteine hydrolase by acyclic sugar adenosine analogue D-eritadenine. Crystal structure of S- adenosylhomocysteine hydrolase complexed with D-eritadenine.

Q9H254	SPTN4_HUMAN	Spectrin beta chain, brain 3	11294830	A new spectrin, beta-IV, has a major truncated isoform that associates with promyelocytic leukemia protein nuclear bodies and the nuclear matrix.

P21730	C5AR_HUMAN	C5a anaphylatoxin chemotactic receptor	2007135	Expression cloning of a receptor for C5a anaphylatoxin on differentiated HL-60 cells.

Q7SXL3	TBP_DANRE	TATA-box-binding protein	17703193	The TATA-binding protein regulates maternal mRNA degradation and differential zygotic transcription in zebrafish.

P62993	GRB2_HUMAN	Growth factor receptor-bound protein 2	1322798	The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling.

Q9UBV8	PEF1_HUMAN	Peflin	11278427	Peflin and ALG-2, members of the penta-EF-hand protein family, form a heterodimer that dissociates in a Ca2+-dependent manner.

Q9VIE6	MCM10_DROME	Protein MCM10 homolog	12808023	Drosophila MCM10 interacts with members of the prereplication complex and is required for proper chromosome condensation.

P97500	MYT1L_MOUSE	Myelin transcription factor 1-like protein	9373037	Myelin transcription factor 1 (Myt1) of the oligodendrocyte lineage, along with a closely related CCHC zinc finger, is expressed in developing neurons in the mammalian central nervous system.

Q94AV5	WIP3_ARATH	WPP domain-interacting protein 3	17600715	Anchorage of plant RanGAP to the nuclear envelope involves novel nuclear-pore-associated proteins.

Q2PS26	ULP1D_ARATH	Ubiquitin-like-specific protease 1D	18849491	Small ubiquitin-like modifier proteases OVERLY TOLERANT TO SALT1 and -2 regulate salt stress responses in Arabidopsis.

O70576	STAG3_MOUSE	Cohesin subunit SA-3	10698974	STAG3, a novel gene encoding a protein involved in meiotic chromosome pairing and location of STAG3-related genes flanking the Williams- Beuren syndrome deletion.

Q9U298	ACH8_CAEEL	Neuronal acetylcholine receptor subunit eat-2	15141086	Measurements of age-related changes of physiological processes that predict lifespan of Caenorhabditis elegans.

O81900	DYT1_ARATH	Transcription factor DYSFUNCTIONAL TAPETUM 1	16831835	Regulation of Arabidopsis tapetum development and function by DYSFUNCTIONAL TAPETUM1 (DYT1) encoding a putative bHLH transcription factor.

Q7RTN6	STRAA_HUMAN	STE20-related kinase adapter protein alpha	12805220	Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD.

P32297	ACHA3_HUMAN	Neuronal acetylcholine receptor subunit alpha-3	11450844	Characterization of the human beta4 nAChR gene and polymorphisms in CHRNA3 and CHRNB4.

Q95RW8	OPTIX_DROME	Protein Optix	9724757	The optx2 homeobox gene is expressed in early precursors of the eye and activates retina-specific genes.

P38297	FZO1_YEAST	Transmembrane GTPase FZO1	11266460	Connection of the mitochondrial outer and inner membranes by Fzo1 is critical for organellar fusion.

Q9Y237	PIN4_HUMAN	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4	19369196	Parvulin (Par14), a peptidyl-prolyl cis-trans isomerase, is a novel rRNA processing factor that evolved in the metazoan lineage.

Q9WVI9	JIP1_MOUSE	C-Jun-amino-terminal kinase-interacting protein 1	11562351	Requirement of the JIP1 scaffold protein for stress-induced JNK activation.

P32354	MCM10_YEAST	Minichromosome maintenance protein 10	9154825	A lesion in the DNA replication initiation factor Mcm10 induces pausing of elongation forks through chromosomal replication origins in Saccharomyces cerevisiae.

Q8WTY4	CPIN1_MOUSE	Anamorsin	14970183	Identification of a cytokine-induced antiapoptotic molecule anamorsin essential for definitive hematopoiesis.

Q60736	ZP3R_MOUSE	Zona pellucida sperm-binding protein 3 receptor	7604284	Tissue- and species-specific expression of sp56, a mouse sperm fertilization protein.

Q8R317	UBQL1_MOUSE	Ubiquilin-1	10549293	Ubiquitin-related proteins regulate interaction of vimentin intermediate filaments with the plasma membrane.

P84275	PA1B_RANPA	Palustrin-1b	11087945	Multiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris.

Q06674	HIM1_YEAST	Protein HIM1	15885712	HIM1, a new yeast Saccharomyces cerevisiae gene playing a role in control of spontaneous and induced mutagenesis.

Q07936	ANXA2_RAT	Annexin A2	8092993	Molecular cloning of a novel N-terminal variant of annexin II from rat basophilic leukaemia cells.

P32839	BCS1_YEAST	Mitochondrial chaperone BCS1	8599931	Internal targeting signal of the BCS1 protein: a novel mechanism of import into mitochondria.

P53705	BUD4_CANAL	Bud site selection protein BUD4	10847632	The Candida albicans INT1 gene facilitates cecal colonization in endotoxin-treated mice.

Q8WUX9	CHMP7_HUMAN	Charged multivesicular body protein 7	16856878	CHMP7, a novel ESCRT-III-related protein, associates with CHMP4b and functions in the endosomal sorting pathway.

Q8JGN5	BI51A_XENLA	Baculoviral IAP repeat-containing protein 5.1-A	16888809	Functional analysis of Survivin in spindle assembly in Xenopus egg extracts.

Q99719	SEPT5_HUMAN	Septin-5	9611266	Structure and expression of the human septin gene HCDCREL-1.

Q7Z3K3	POGZ_HUMAN	Pogo transposable element with ZNF domain	10976766	A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening.

Q9N3Z3	CHK1_CAEEL	Serine/threonine-protein kinase chk-1	15326393	chk-1 is an essential gene and is required for an S-M checkpoint during early embryogenesis.

Q9NZJ7	MTCH1_HUMAN	Mitochondrial carrier homolog 1	10551805	Identification of a novel PSD-95/Dlg/ZO-1 (PDZ)-like protein interacting with the C terminus of presenilin-1.

Q23972	SMG_DROME	Protein Smaug	14685270	Drosophila Cup is an eIF4E-binding protein that functions in Smaug- mediated translational repression.

P48164	RS7B_YEAST	40S ribosomal protein S7-B	15590835	The small-subunit processome is a ribosome assembly intermediate.

Q6A332	ALY3_ARATH	Protein ALWAYS EARLY 3	19962994	PAH-domain-specific interactions of the Arabidopsis transcription coregulator SIN3-LIKE1 (SNL1) with telomere-binding protein 1 and ALWAYS EARLY2 Myb-DNA binding factors.

Q38967	AAP2_ARATH	Amino acid permease 2	7608199	Substrate specificity and expression profile of amino acid transporters (AAPs) in Arabidopsis.

P48593	E631_DROME	Calcium-binding protein E63-1	7671827	The Drosophila 63F early puff contains E63-1, an ecdysone-inducible gene that encodes a novel Ca(2+)-binding protein.

Q9ES45	DUOX2_RAT	Dual oxidase 2	12538618	Identification of a truncated dual oxidase 2 (DUOX2) messenger ribonucleic acid (mRNA) in two rat thyroid cell lines. Insulin and forskolin regulation of DUOX2 mRNA levels in FRTL-5 cells and porcine thyrocytes.

Q9DAT5	MTU1_MOUSE	Mitochondrial tRNA-specific 2-thiouridylase 1	14746906	Identification and characterization of mouse TRMU gene encoding the mitochondrial 5-methylaminomethyl-2-thiouridylate-methyltransferase.

Q9Y705	ALP4_SCHPO	Spindle pole body component alp4	11952833	The gamma-tubulin complex protein Alp4 provides a link between the metaphase checkpoint and cytokinesis in fission yeast.

Q99288	DET1_YEAST	Putative phosphoglycerate mutase DET1	14562095	Global analysis of protein localization in budding yeast.

P37996	ARL3_RAT	ADP-ribosylation factor-like protein 3	8034651	ADP-ribosylation factor (ARF)-like 3, a new member of the ARF family of GTP-binding proteins cloned from human and rat tissues.

P09052	VASA1_DROME	ATP-dependent RNA helicase vasa, isoform A	8026330	Localization of vasa protein to the Drosophila pole plasm is independent of its RNA-binding and helicase activities.

Q91XR9	GPX42_MOUSE	Phospholipid hydroperoxide glutathione peroxidase, nuclear	11344099	Identification of a specific sperm nuclei selenoenzyme necessary for protamine thiol cross-linking during sperm maturation.

Q9SNN0	SPE1_ORYSJ	Arginine decarboxylase 1	16769152	Molecular cloning and characterization of an arginine decarboxylase gene up-regulated by chilling stress in rice seedlings.

Q9VAN6	SLBP_DROME	Histone RNA hairpin-binding protein	11157774	Drosophila stem loop binding protein coordinates accumulation of mature histone mRNA with cell cycle progression.

Q06340	ESC2_YEAST	Protein ESC2	11090616	A histone variant, Htz1p, and a Sir1p-like protein, Esc2p, mediate silencing at HMR.

P50942	INP52_YEAST	Inositol-1,4,5-trisphosphate 5-phosphatase 2	11094088	The yeast inositol polyphosphate 5-phosphatases inp52p and inp53p translocate to actin patches following hyperosmotic stress: mechanism for regulating phosphatidylinositol 4,5-bisphosphate at plasma membrane invaginations.

Q00972	BCKD_RAT	[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial	1377677	Branched-chain alpha-ketoacid dehydrogenase kinase. Molecular cloning, expression, and sequence similarity with histidine protein kinases.

Q42384	PRL1_ARATH	Protein pleiotropic regulatory locus 1	9765207	Pleiotropic control of glucose and hormone responses by PRL1, a nuclear WD protein, in Arabidopsis.

O04379	AGO1_ARATH	Protein argonaute	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

P11844	CRGA_HUMAN	Gamma-crystallin A	3670288	Gamma-crystallins of the human eye lens: expression analysis of five members of the gene family.

Q12374	NCA2_YEAST	Nuclear control of ATPase protein 2	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q39023	MPK3_ARATH	Mitogen-activated protein kinase 3	12506203	NDP kinase 2 interacts with two oxidative stress-activated MAPKs to regulate cellular redox state and enhances multiple stress tolerance in transgenic plants.

Q99N93	RM16_MOUSE	39S ribosomal protein L16, mitochondrial	11279069	Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria.

Q9C103	EME1_SCHPO	Crossover junction endonuclease eme1	12084712	Mus81-Eme1 and Rqh1 involvement in processing stalled and collapsed replication forks.

P27105	STOM_HUMAN	Erythrocyte band 7 integral membrane protein	1547348	Isolation of cDNA coding for an ubiquitous membrane protein deficient in high Na+, low K+ stomatocytic erythrocytes.

Q54I36	PYK3_DICDI	Dual specificity protein kinase pyk3	8898113	Classification of tyrosine kinases from Dictyostelium discoideum with two distinct, complete or incomplete catalytic domains.

Q15796	SMAD2_HUMAN	Mothers against decapentaplegic homolog 2	17099224	Potentiation of Smad-mediated transcriptional activation by the RNA- binding protein RBPMS.

P78871	RST2_SCHPO	Zinc finger protein rst2	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

P30185	DHR18_ARATH	Dehydrin Rab18	1463831	The expression of a rab-related gene, rab18, is induced by abscisic acid during the cold acclimation process of Arabidopsis thaliana (L.) Heynh.

Q9ES67	ARHGB_RAT	Rho guanine nucleotide exchange factor 11	11242047	Modulation of the neuronal glutamate transporter EAAT4 by two interacting proteins.

Q9C8K2	AB12G_ARATH	ABC transporter G family member 12	17951461	The Arabidopsis DESPERADO/AtWBC11 transporter is required for cutin and wax secretion.

Q9FUR2	IP5P2_ARATH	Type I inositol-1,4,5-trisphosphate 5-phosphatase 2	11340187	Arabidopsis PLC1 is required for secondary responses to abscisic acid signals.

P54704	SP85_DICDI	Spore coat protein SP85	17416892	Role of SP65 in assembly of the Dictyostelium discoideum spore coat.

P34243	HCS1_YEAST	DNA polymerase alpha-associated DNA helicase A	9341218	Yeast DNA helicase A: cloning, expression, purification, and enzymatic characterization.

P53838	BOR1_YEAST	Boron transporter 1	17459946	Transport and regulatory characteristics of the yeast bicarbonate transporter homolog Bor1p.

Q9VDW6	DMDA_DROME	Dystrophin, isoforms A/C/F/G/H	17355978	A putative Src homology 3 domain binding motif but not the C-terminal dystrophin WW domain binding motif is required for dystroglycan function in cellular polarity in Drosophila.

Q9SYM4	TPS1_ARATH	Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 1	15667326	The role of trehalose-6-phosphate synthase in Arabidopsis embryo development.

P29459	IL12A_HUMAN	Interleukin-12 subunit alpha	10899108	Charged residues dominate a unique interlocking topography in the heterodimeric cytokine interleukin-12.

Q8MVR1	GBPC_DICDI	Cyclic GMP-binding protein C	15827084	RasGEF-containing proteins GbpC and GbpD have differential effects on cell polarity and chemotaxis in Dictyostelium.

Q9Y4L1	HYOU1_HUMAN	Hypoxia up-regulated protein 1	9020069	Cloning and expression of cDNA encoding the human 150 kDa oxygen- regulated protein, ORP150.

Q9SL79	CAF1P_ARATH	CRS2-associated factor 1, chloroplastic	17071648	Arabidopsis orthologs of maize chloroplast splicing factors promote splicing of orthologous and species-specific group II introns.

Q9US52	BQT2_SCHPO	Telomere bouquet protein 2	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

Q15599	NHRF2_HUMAN	Na(+)/H(+) exchange regulatory cofactor NHE-RF2	9054412	The human testis determining factor SRY binds a nuclear factor containing PDZ protein interaction domains.

P41823	SY65_APLCA	Synaptotagmin-1	15056279	Identification and characterization of a novel C2B splice variant of synaptotagmin I.

P63241	IF5A1_HUMAN	Eukaryotic translation initiation factor 5A-1	17213197	Specificity of the deoxyhypusine hydroxylase-eukaryotic translation initiation factor (eIF5A) interaction: identification of amino acid residues of the enzyme required for binding of its substrate, deoxyhypusine-containing eIF5A.

O54853	KCNH6_RAT	Potassium voltage-gated channel subfamily H member 6	9390998	Identification of two nervous system-specific members of the erg potassium channel gene family.

Q9H6Q4	NARFL_HUMAN	Cytosolic Fe-S cluster assembly factor NARFL	16956324	IOP1, a novel hydrogenase-like protein that modulates hypoxia- inducible factor-1alpha activity.

Q12132	USV1_YEAST	Nutrient and stress factor 1	12740579	Module networks: identifying regulatory modules and their condition- specific regulators from gene expression data.

P48025	KSYK_MOUSE	Tyrosine-protein kinase SYK	19124738	RhoH plays critical roles in Fc epsilon RI-dependent signal transduction in mast cells.

O43143	DHX15_HUMAN	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15	9388478	Cloning and characterization of a putative human RNA helicase gene of the DEAH-box protein family.

Q16610	ECM1_HUMAN	Extracellular matrix protein 1	16512877	Extracellular matrix protein 1 inhibits the activity of matrix metalloproteinase 9 through high-affinity protein/protein interactions.

Q94FY7	TOCC_ARATH	Tocopherol cyclase, chloroplastic	16461379	Protein profiling of plastoglobules in chloroplasts and chromoplasts. A surprising site for differential accumulation of metabolic enzymes.

Q92754	AP2C_HUMAN	Transcription factor AP-2 gamma	12072434	Transcription factor AP-2 interacts with the SUMO-conjugating enzyme UBC9 and is sumolated in vivo.

Q9QWH1	PHC2_MOUSE	Polyhomeotic-like protein 2	12034499	The mouse Edr2 (Mph2) gene has two forms of mRNA encoding 90- and 36- kDa polypeptides.

Q9UTA9	YL89_SCHPO	Uncharacterized methyltransferase C25B8.09	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9BTM9	URM1_HUMAN	Ubiquitin-related modifier 1 homolog	19017811	A functional proteomics approach links the ubiquitin-related modifier Urm1 to a tRNA modification pathway.

P52074	GLCF_ECOLI	Glycolate oxidase iron-sulfur subunit	8606183	glc locus of Escherichia coli: characterization of genes encoding the subunits of glycolate oxidase and the glc regulator protein.

P46971	PMT4_YEAST	Dolichyl-phosphate-mannose--protein mannosyltransferase 4	8918452	The PMT gene family: protein O-glycosylation in Saccharomyces cerevisiae is vital.

P12004	PCNA_HUMAN	Proliferating cell nuclear antigen	15543136	The Williams syndrome transcription factor interacts with PCNA to target chromatin remodelling by ISWI to replication foci.

Q9SX99	OSB1_ARATH	Protein OSB1, mitochondrial	17189341	The plant-specific ssDNA binding protein OSB1 is involved in the stoichiometric transmission of mitochondrial DNA in Arabidopsis.

P36152	DRE2_YEAST	Fe-S cluster assembly protein DRE2	19194512	A newly identified essential complex, Dre2-Tah18, controls mitochondria integrity and cell death after oxidative stress in yeast.

P38785	GIC1_YEAST	GTPase-interacting component 1	9367980	Novel Cdc42-binding proteins Gic1 and Gic2 control cell polarity in yeast.

P41778	PBX1_MOUSE	Pre-B-cell leukemia transcription factor 1	9315626	Meis proteins are major in vivo DNA binding partners for wild-type but not chimeric Pbx proteins.

Q9P6R8	CWC24_SCHPO	Pre-mRNA-splicing factor cwc24	11884590	Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

P62882	GBB5_RAT	Guanine nucleotide-binding protein subunit beta-5	9622245	Distribution of heterotrimeric G-protein beta and gamma subunits in the rat brain.

Q92993	KAT5_HUMAN	Histone acetyltransferase KAT5	16387653	ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.

Q8TCU6	PREX1_HUMAN	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein	11955434	P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine- nucleotide exchange factor for Rac.

Q9FRV1	CHIA_SECCE	Basic endochitinase A	11826968	Localization, accumulation, and antifungal activity of chitinases in rye (Secale cereale) seed.

Q9FRV4	NAC54_ARATH	Protein CUP-SHAPED COTYLEDON 1	9212461	Genes involved in organ separation in Arabidopsis: an analysis of the cup-shaped cotyledon mutant.

Q9UF02	CCG5_HUMAN	Voltage-dependent calcium channel gamma-5 subunit	10613843	Identification of three novel Ca(2+) channel gamma subunit genes reveals molecular diversification by tandem and chromosome duplication.

Q9XYF4	ICENC_DROME	Caspase Nc	10675329	The Drosophila caspase DRONC is regulated by DIAP1.

Q9UBY8	CLN8_HUMAN	Protein CLN8	10508524	The neuronal ceroid lipofuscinoses in human EPMR and mnd mutant mice are associated with mutations in CLN8.

Q12030	TAF10_YEAST	Transcription initiation factor TFIID subunit 10	12446794	The novel SLIK histone acetyltransferase complex functions in the yeast retrograde response pathway.

P51797	CLCN6_HUMAN	Chloride transport protein 6	9224655	Alternative splicing of ClC-6 (a member of the ClC chloride-channel family) transcripts generates three truncated isoforms one of which, ClC-6c, is kidney-specific.

P27658	CO8A1_HUMAN	Collagen alpha-1(VIII) chain	2029894	The complete primary structure of the human alpha 1 (VIII) chain and assignment of its gene (COL8A1) to chromosome 3.

Q8TDR0	MIPT3_HUMAN	TRAF3-interacting protein 1	10791955	MIP-T3, a novel protein linking tumor necrosis factor receptor- associated factor 3 to the microtubule network.

Q9Y672	ALG6_HUMAN	Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase	11106564	Reduced heparan sulfate accumulation in enterocytes contributes to protein-losing enteropathy in a congenital disorder of glycosylation.

Q9USZ3	RUXE_SCHPO	Small nuclear ribonucleoprotein E	17264129	Proteomic analysis of the U1 snRNP of Schizosaccharomyces pombe reveals three essential organism-specific proteins.

Q9M268	NGA2_ARATH	B3 domain-containing transcription factor NGA2	16603651	Endogenous and synthetic microRNAs stimulate simultaneous, efficient, and localized regulation of multiple targets in diverse species.

P60983	GMFB_HUMAN	Glia maturation factor beta	7598724	Phorbol ester stimulates rapid intracellular phosphorylation of glia maturation factor.

O14777	NDC80_HUMAN	Kinetochore protein NDC80 homolog	16732327	Hec1 sequentially recruits Zwint-1 and ZW10 to kinetochores for faithful chromosome segregation and spindle checkpoint control.

P17839	AG_ARATH	Floral homeotic protein AGAMOUS	1973265	The protein encoded by the Arabidopsis homeotic gene agamous resembles transcription factors.

Q09892	HOG1_SCHPO	Mitogen-activated protein kinase sty1	12861001	Identification of cdc37 as a novel regulator of the stress-responsive mitogen-activated protein kinase.

Q91XT6	TAC2N_MOUSE	Tandem C2 domains nuclear protein	11526914	Tac2-N, an atypical C-type tandem C2 protein localized in the nucleus.

Q8T390	SH3G3_DROME	Endophilin-A	11955450	Endophilin mutations block clathrin-mediated endocytosis but not neurotransmitter release.

P62136	PP1A_HUMAN	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit	8392016	Cloning and characterization of a human protein phosphatase 1- encoding cDNA.

P78859	ISA1_SCHPO	Iron-sulfur assembly protein 1	11941510	Iron-sulfur cluster biosynthesis: characterization of Schizosaccharomyces pombe Isa1.

Q8RX88	FACE1_ARATH	CAAX prenyl protease 1 homolog	12039957	The Arabidopsis AtSTE24 is a CAAX protease with broad substrate specificity.

O60341	KDM1A_HUMAN	Lysine-specific histone demethylase 1A	15620353	Histone demethylation mediated by the nuclear amine oxidase homolog LSD1.

P82999	GSTE1_PSEUO	Glutathione S-transferase	11900268	Occurence and properties of glutathione S-transferases in phenol- degrading Pseudomonas strains.

Q27J49	BNP_LACMU	Bradykinin-potentiating and C-type natriuretic peptides	15876444	Identification of novel bradykinin-potentiating peptides and C-type natriuretic peptide from Lachesis muta venom.

Q96KB5	TOPK_HUMAN	Lymphokine-activated killer T-cell-originated protein kinase	17482142	Attenuation of DNA damage checkpoint by PBK, a novel mitotic kinase, involves protein-protein interaction with tumor suppressor p53.

Q6VH22	IF172_MOUSE	Intraflagellar transport protein 172 homolog	16061793	Cilia and Hedgehog responsiveness in the mouse.

Q9QYL7	ABT1_MOUSE	Activator of basal transcription 1	10648625	A novel TATA-binding protein-binding protein, ABT1, activates basal transcription and has a yeast homolog that is essential for growth.

P16284	PECA1_HUMAN	Platelet endothelial cell adhesion molecule	19342684	A novel and critical role for tyrosine 663 in platelet endothelial cell adhesion molecule-1 trafficking and transendothelial migration.

Q8WVK7	SKA2_HUMAN	Spindle and kinetochore-associated protein 2	17093495	Timely anaphase onset requires a novel spindle and kinetochore complex comprising Ska1 and Ska2.

Q61107	GBP4_MOUSE	Guanylate-binding protein 4	9659399	Cloning, expression, and characterization of a novel guanylate- binding protein, GBP3 in murine erythroid progenitor cells.

P36022	DYHC_YEAST	Dynein heavy chain, cytoplasmic	15642746	The offloading model for dynein function: differential function of motor subunits.

O00716	E2F3_HUMAN	Transcription factor E2F3	8246996	The retinoblastoma protein binds to a family of E2F transcription factors.

P53104	ATG1_YEAST	Serine/threonine-protein kinase ATG1	12589048	Chemical genetic analysis of Apg1 reveals a non-kinase role in the induction of autophagy.

Q7Z7C8	TAF8_HUMAN	Transcription initiation factor TFIID subunit 8	14580349	The TBN protein, which is essential for early embryonic mouse development, is an inducible TAFII implicated in adipogenesis.

O60260	PRKN2_HUMAN	E3 ubiquitin-protein ligase parkin	10888878	Familial Parkinson disease gene product, parkin, is a ubiquitin- protein ligase.

O45952	CSC1_CAEEL	Chromosome segregation and cytokinesis defective protein 1	12707312	CSC-1: a subunit of the Aurora B kinase complex that binds to the survivin-like protein BIR-1 and the incenp-like protein ICP-1.

P34271	CUP4_CAEEL	Acetylcholine receptor-like protein cup-4	15936276	Endocytosis function of a ligand-gated ion channel homolog in Caenorhabditis elegans.

P24903	CP2F1_HUMAN	Cytochrome P450 2F1	1974816	The human CYP2F gene subfamily: identification of a cDNA encoding a new cytochrome P450, cDNA-directed expression, and chromosome mapping.

Q7TQ33	RGMB_MOUSE	RGM domain family member B	14749425	Repulsive guidance molecule (RGM) gene function is required for neural tube closure but not retinal topography in the mouse visual system.

P24468	COT2_HUMAN	COUP transcription factor 2	1899293	Regulation of the apolipoprotein AI gene by ARP-1, a novel member of the steroid receptor superfamily.

Q9UT10	YLW5_SCHPO	Uncharacterized GTP-binding protein P8A3.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9LX66	HERK_ARATH	Receptor-like protein kinase HERK 1	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P20081	FKBP_YEAST	FK506-binding protein 1	10049913	Hmo1p, a high mobility group 1/2 homolog, genetically and physically interacts with the yeast FKBP12 prolyl isomerase.

P29478	SEC65_YEAST	Signal recognition particle subunit SEC65	1313948	The S. cerevisiae SEC65 gene encodes a component of yeast signal recognition particle with homology to human SRP19.

Q9Z330	DNMT1_RAT	DNA (cytosine-5)-methyltransferase 1	8667030	Molecular cloning and characterization of annexin V-binding proteins with highly hydrophilic peptide structure.

Q8VYR7	BOR1_ARATH	Boron transporter 1	16103374	Endocytosis and degradation of BOR1, a boron transporter of Arabidopsis thaliana, regulated by boron availability.

O13370	DED1_SCHPO	ATP-dependent RNA helicase ded1	9832516	Suppressors of cdc25p overexpression identify two pathways that influence the G2/M checkpoint in fission yeast.

P39905	GDNF_HUMAN	Glial cell line-derived neurotrophic factor	9811930	Analysis of the human GDNF gene reveals an inducible promoter, three exons, a triplet repeat within the 3'-UTR and alternative splice products.

P20095	PRP2_YEAST	Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2	2251118	Interactions of PRP2 protein with pre-mRNA splicing complexes in Saccharomyces cerevisiae.

O13754	CNS1_SCHPO	Hsp70/Hsp90 co-chaperone cns1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9XGN1	TTG1_ARATH	Protein TRANSPARENT TESTA GLABRA 1	14561633	A contradictory GLABRA3 allele helps define gene interactions controlling trichome development in Arabidopsis.

Q15075	EEA1_HUMAN	Early endosome antigen 1	11870209	The small GTPase Rab22 interacts with EEA1 and controls endosomal membrane trafficking.

O43011	SYH_SCHPO	Histidyl-tRNA synthetase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9U6L5	PEB1_DROME	Ejaculatory bulb-specific protein 1	11267893	Identification and characterization of the major Drosophila melanogaster mating plug protein.

Q09146	HBA1_SCHPO	Brefeldin A resistance protein	8621569	Characterization of a nuclear protein conferring brefeldin A resistance in Schizosaccharomyces pombe.

P97849	S27A1_RAT	Long-chain fatty acid transport protein 1	9375787	Molecular cloning of fatty acid-transport protein cDNA from rat.

O81283	TC159_ARATH	Translocase of chloroplast 159, chloroplastic	12938931	Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis.

Q8TGM6	TAR1_YEAST	Protein TAR1	12414727	A novel mitochondrial protein, Tar1p, is encoded on the antisense strand of the nuclear 25S rDNA.

Q9UPN3	MACF1_HUMAN	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5	10529403	Molecular cloning of macrophin, a human homologue of Drosophila kakapo with a close structural similarity to plectin and dystrophin.

Q5SMG8	MGTE_THET8	Magnesium transporter mgtE	17700703	Crystal structure of the MgtE Mg(2+) transporter.

P00813	ADA_HUMAN	Adenosine deaminase	8101391	Direct association of adenosine deaminase with a T cell activation antigen, CD26.

Q80W66	HS3S2_RAT	Heparan sulfate glucosamine 3-O-sulfotransferase 2	12601002	Diurnal pineal 3-O-sulphotransferase 2 expression controlled by beta- adrenergic repression.

P17488	HM13_CAEEL	Homeobox protein ceh-13	10068646	Anterior organization of the Caenorhabditis elegans embryo by the labial-like Hox gene ceh-13.

O43653	PSCA_HUMAN	Prostate stem cell antigen	9465086	Prostate stem cell antigen: a cell surface marker overexpressed in prostate cancer.

P00480	OTC_HUMAN	Ornithine carbamoyltransferase, mitochondrial	6372096	Structure and expression of a complementary DNA for the nuclear coded precursor of human mitochondrial ornithine transcarbamylase.

Q03100	CYAA_DICDI	Adenylate cyclase, aggregation specific	16267269	Phosphoinositide 3-kinase activity controls the chemoattractant- mediated activation and adaptation of adenylyl cyclase.

P35570	IRS1_RAT	Insulin receptor substrate 1	8491186	The SH2/SH3 domain-containing protein GRB2 interacts with tyrosine- phosphorylated IRS1 and Shc: implications for insulin control of ras signalling.

P10916	MLRV_HUMAN	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform	8673105	Mutations in either the essential or regulatory light chains of myosin are associated with a rare myopathy in human heart and skeletal muscle.

Q64573	EST4_RAT	Liver carboxylesterase 4	7961958	Rat kidney carboxylesterase. Cloning, sequencing, cellular localization, and relationship to rat liver hydrolase.

P32335	MSS51_YEAST	Protein MSS51, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

P09884	DPOLA_HUMAN	DNA polymerase alpha catalytic subunit	3359994	Human DNA polymerase alpha gene expression is cell proliferation dependent and its primary structure is similar to both prokaryotic and eukaryotic replicative DNA polymerases.

O14187	SPP42_SCHPO	Pre-mRNA-splicing factor spp42	16133344	Multiple genetic and biochemical interactions of Brr2, Prp8, Prp31, Prp1 and Prp4 kinase suggest a function in the control of the activation of spliceosomes in Schizosaccharomyces pombe.

Q96BT7	ALKB8_HUMAN	Alkylated DNA repair protein alkB homolog 8	20308323	Human AlkB homolog ABH8 is a tRNA methyltransferase required for wobble uridine modification and DNA damage survival.

Q27954	COPA_BOVIN	Coatomer subunit alpha	8858162	Architecture of coatomer: molecular characterization of delta-COP and protein interactions within the complex.

Q9V464	ASF1_DROME	Histone chaperone asf1	11533245	Interaction between the Drosophila CAF-1 and ASF1 chromatin assembly factors.

Q96WW2	MUG93_SCHPO	Meiotically up-regulated gene 93 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P04433	KV309_HUMAN	Ig kappa chain V-III region VG	6440122	Immunoglobulin genes of different subgroups are interdigitated within the VK locus.

O74857	RPC4_SCHPO	DNA-directed RNA polymerase III subunit rpc4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P11655	SEC12_YEAST	Guanine nucleotide-exchange factor SEC12	8583945	Expression, purification, and assay of Sec12p: a Sar1p-specific GDP dissociation stimulator.

P35558	PCKGC_HUMAN	Phosphoenolpyruvate carboxykinase, cytosolic [GTP]	11851336	Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site.

Q8WYB5	MYST4_HUMAN	Histone acetyltransferase MYST4	11965546	MOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2.

Q10168	NSP1_SCHPO	Nucleoporin nsp1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8IZE3	PACE1_HUMAN	Protein-associating with the carboxyl-terminal domain of ezrin	12651155	PACE-1, a novel protein that interacts with the C-terminal domain of ezrin.

Q12913	PTPRJ_HUMAN	Receptor-type tyrosine-protein phosphatase eta	7937872	Expression of DEP-1, a receptor-like protein-tyrosine-phosphatase, is enhanced with increasing cell density.

P48200	IREB2_HUMAN	Iron-responsive element-binding protein 2	19762596	Control of iron homeostasis by an iron-regulated ubiquitin ligase.

Q9P2Y4	ZN219_HUMAN	Zinc finger protein 219	10819330	Isolation and characterization of a novel zinc finger gene, ZNF219, and mapping to the human chromosome 14q11 region.

P32238	CCKAR_HUMAN	Cholecystokinin receptor type A	8503909	Molecular cloning and functional expression of the human gallbladder cholecystokinin A receptor.

P05230	FGF1_HUMAN	Heparin-binding growth factor 1	10618369	Structural interactions of fibroblast growth factor receptor with its ligands.

Q00218	AROG_ARATH	Phospho-2-dehydro-3-deoxyheptonate aldolase 2, chloroplastic	1681544	Differential induction of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase genes in Arabidopsis thaliana by wounding and pathogenic attack.

P40460	NDC80_YEAST	Kinetochore protein NDC80	9585415	Analysis of the Saccharomyces spindle pole by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry.

P43246	MSH2_HUMAN	DNA mismatch repair protein Msh2	14657349	MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation.

P21581	SCF_RAT	Kit ligand	2208279	Primary structure and functional expression of rat and human stem cell factor DNAs.

P0C7L2	PAAJ_ECOLI	Beta-ketoadipyl-CoA thiolase	17259607	Characterization of the last step of the aerobic phenylacetic acid degradation pathway.

Q8AY29	CEGTA_XENLA	Ceramide glucosyltransferase-A	18095347	Cloning and functional characterization of two key enzymes of glycosphingolipid biosynthesis in the amphibian Xenopus laevis.

O94561	PRX_SCHPO	Peroxiredoxin C1773.02c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O94769	ECM2_HUMAN	Extracellular matrix protein 2	9790758	Identification of a novel gene (ECM2) encoding a putative extracellular matrix protein expressed predominantly in adipose and female-specific tissues and its chromosomal localization to 9q22.3.

P34239	LST4_YEAST	Protein LST4	9409822	Control of amino acid permease sorting in the late secretory pathway of Saccharomyces cerevisiae by SEC13, LST4, LST7 and LST8.

Q16676	FOXD1_HUMAN	Forkhead box protein D1	8702877	Characterization of the human forkhead gene FREAC-4. Evidence for regulation by Wilms' tumor suppressor gene (WT-1) and p53.

Q99393	IZH4_YEAST	ADIPOR-like receptor IZH4	15060275	Metalloregulation of yeast membrane steroid receptor homologs.

P05177	CP1A2_HUMAN	Cytochrome P450 1A2	17311915	Adaptations for the oxidation of polycyclic aromatic hydrocarbons exhibited by the structure of human P450 1A2.

P43573	BUD27_YEAST	Bud site selection protein 27	14562095	Global analysis of protein localization in budding yeast.

P33643	RLUD_ECOLI	Ribosomal large subunit pseudouridine synthase D	9814761	A pseudouridine synthase required for the formation of two universally conserved pseudouridines in ribosomal RNA is essential for normal growth of Escherichia coli.

Q95017	UBC9_CAEEL	SUMO-conjugating enzyme UBC9	15107848	SUMO modification is required for in vivo Hox gene regulation by the Caenorhabditis elegans Polycomb group protein SOP-2.

A2A935	PRD16_MOUSE	PR domain zinc finger protein 16	17618855	Transcriptional control of brown fat determination by PRDM16.

Q14439	GP176_HUMAN	Probable G-protein coupled receptor 176	7893747	cDNA cloning of a putative G protein-coupled receptor from brain.

O94903	PROSC_HUMAN	Proline synthase co-transcribed bacterial homolog protein	10496079	Cloning and characterization of human and mouse PROSC (proline synthetase co-transcribed) genes.

Q7T019	DZIP1_DANRE	Zinc finger protein Dzip1	15115751	The zebrafish iguana locus encodes Dzip1, a novel zinc-finger protein required for proper regulation of Hedgehog signaling.

O13746	YDRI_SCHPO	Uncharacterized protein C16E8.18	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NSN8	SNTG1_HUMAN	Gamma-1-syntrophin	10747910	Gamma1- and gamma2-syntrophins, two novel dystrophin-binding proteins localized in neuronal cells.

Q92540	SMG7_HUMAN	Protein SMG7	15721257	SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway.

P32643	TMT1_YEAST	Trans-aconitate 3-methyltransferase	11695919	Identification of the gene and characterization of the activity of the trans-aconitate methyltransferase from Saccharomyces cerevisiae.

Q9LDC0	FKB42_ARATH	42 kDa peptidyl-prolyl isomerase	12410806	Characterization of Arabidopsis thaliana AtFKBP42 that is membrane- bound and interacts with Hsp90.

P33176	KINH_HUMAN	Kinesin-1 heavy chain	8606779	Crystal structure of the kinesin motor domain reveals a structural similarity to myosin.

Q13129	RLF_HUMAN	Zinc finger protein Rlf	8545128	The rearranged L-myc fusion gene (RLF) encodes a Zn-15 related zinc finger protein.

B2ZZS9	WDR55_ORYLA	WD repeat-containing protein 55	18769712	WDR55 is a nucleolar modulator of ribosomal RNA synthesis, cell cycle progression, and teleost organ development.

Q9NV58	RN19A_HUMAN	E3 ubiquitin-protein ligase RNF19A	10976766	A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening.

P33400	PACC_YEAST	pH-response transcription factor pacC/RIM101	8367297	Molecular characterization of the yeast meiotic regulatory gene RIM1.

Q9R1X4	TIM_MOUSE	Protein timeless homolog	9856465	Mammalian circadian autoregulatory loop: a timeless ortholog and mPer1 interact and negatively regulate CLOCK-BMAL1-induced transcription.

P97541	HSPB6_RAT	Heat shock protein beta-6	19646995	Crystal structures of alpha-crystallin domain dimers of alphaB- crystallin and Hsp20.

P54577	SYYC_HUMAN	Tyrosyl-tRNA synthetase, cytoplasmic	9162081	Human tyrosyl-tRNA synthetase shares amino acid sequence homology with a putative cytokine.

Q61086	FZD3_MOUSE	Frizzled-3	11407985	Characterization of mouse frizzled-3 expression in hair follicle development and identification of the human homolog in keratinocytes.

P10107	ANXA1_MOUSE	Annexin A1	14506282	Dysferlin interacts with annexins A1 and A2 and mediates sarcolemmal wound-healing.

O13765	DBR1_SCHPO	Lariat debranching enzyme	9001235	Severe growth defect in a Schizosaccharomyces pombe mutant defective in intron lariat degradation.

Q9LE82	RAGP1_ARATH	RAN GTPase-activating protein 1	17600715	Anchorage of plant RanGAP to the nuclear envelope involves novel nuclear-pore-associated proteins.

P13796	PLSL_HUMAN	Plastin-2	2111166	Characterization of interleukin 2 stimulated 65-kilodalton phosphoprotein in human T cells.

Q9UQ84	EXO1_HUMAN	Exonuclease 1	10856833	Identification of factors interacting with hMSH2 in the fetal liver utilizing the yeast two-hybrid system. In vivo interaction through the C-terminal domains of hEXO1 and hMSH2 and comparative expression analysis.

Q20347	MKK4_CAEEL	MAP kinase kinase mkk-4	15707898	Regulation of a DLK-1 and p38 MAP kinase pathway by the ubiquitin ligase RPM-1 is required for presynaptic development.

P0ACI6	ASNC_ECOLI	Regulatory protein AsnC	2864330	AsnC: an autogenously regulated activator of asparagine synthetase A transcription in Escherichia coli.

Q8NHM4	TRY6_HUMAN	Putative trypsin-6	15313892	S100 family members and trypsinogens are predictors of distant metastasis and survival in early-stage non-small cell lung cancer.

P53762	ARNT_MOUSE	Aryl hydrocarbon receptor nuclear translocator	11025203	Isolation and characterization of AINT: a novel ARNT interacting protein expressed during murine embryonic development.

Q92903	CDS1_HUMAN	Phosphatidate cytidylyltransferase 1	8863531	Cloning of CDP-diacylglycerol synthase from a human neuronal cell line.

P04629	NTRK1_HUMAN	High affinity nerve growth factor receptor	9290260	Structure and organization of the human TRKA gene encoding a high affinity receptor for nerve growth factor.

P01148	GON1_HUMAN	Progonadoliberin-1	2867548	Isolation of the gene and hypothalamic cDNA for the common precursor of gonadotropin-releasing hormone and prolactin release-inhibiting factor in human and rat.

O13529	ECM12_YEAST	Protein ECM12	9335584	Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae.

Q8WW12	PCNP_HUMAN	PEST proteolytic signal-containing nuclear protein	14741369	NIRF is a ubiquitin ligase that is capable of ubiquitinating PCNP, a PEST-containing nuclear protein.

B9V5F5	CE63A_XENLA	Centrosomal protein of 63 kDa-A	19182792	An ATM- and ATR-dependent checkpoint inactivates spindle assembly by targeting CEP63.

P60174	TPIS_HUMAN	Triosephosphate isomerase	2579079	Human triosephosphate isomerase cDNA and protein structure. Studies of triosephosphate isomerase deficiency in man.

P01123	YPT1_YEAST	GTP-binding protein YPT1	11943201	Identification of the novel proteins Yip4p and Yip5p as Rab GTPase interacting factors.

P46013	KI67_HUMAN	Antigen KI-67	8227122	The cell proliferation-associated antigen of antibody Ki-67: a very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins.

Q9WUN2	TBK1_MOUSE	Serine/threonine-protein kinase TBK1	15661922	Immune activation of type I IFNs by Listeria monocytogenes occurs independently of TLR4, TLR2, and receptor interacting protein 2 but involves TNFR-associated NF kappa B kinase-binding kinase 1.

Q96GD4	AURKB_HUMAN	Serine/threonine-protein kinase 12	12689593	Phosphorylation by aurora B converts MgcRacGAP to a RhoGAP during cytokinesis.

Q03162	MUB1_YEAST	MYND-type zinc finger protein MUB1	18070918	Genome-wide analysis identifies MYND-domain protein Mub1 as an essential factor for Rpn4 ubiquitylation.

P23443	KS6B1_HUMAN	Ribosomal protein S6 kinase beta-1	1922062	Cloning and expression of two human p70 S6 kinase polypeptides differing only at their amino termini.

P08195	4F2_HUMAN	4F2 cell-surface antigen heavy chain	3476959	Molecular cloning of complementary DNAs encoding the heavy chain of the human 4F2 cell-surface antigen: a type II membrane glycoprotein involved in normal and neoplastic cell growth.

Q9Z1Y0	RHOV_RAT	Rho-related GTP-binding protein RhoV	9778532	Chp, a homologue of the GTPase Cdc42Hs, activates the JNK pathway and is implicated in reorganizing the actin cytoskeleton.

Q04748	SOV1_YEAST	Protein SOV1, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q8TCJ2	STT3B_HUMAN	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B	12887896	Oligosaccharyltransferase isoforms that contain different catalytic STT3 subunits have distinct enzymatic properties.

Q7Z628	ARHG8_HUMAN	Neuroepithelial cell-transforming gene 1 protein	8649828	Isolation of a novel oncogene, NET1, from neuroepithelioma cells by expression cDNA cloning.

O70220	FOXQ1_MOUSE	Forkhead box protein Q1	11309849	The winged helix/forkhead transcription factor Foxq1 regulates differentiation of hair in satin mice.

P52569	CTR2_HUMAN	Low affinity cationic amino acid transporter 2	8954799	Molecular cloning, tissue distribution, and chromosomal localization of human cationic amino acid transporter 2 (HCAT2).

Q12033	PALA_YEAST	pH-response regulator protein palA/RIM20	14562095	Global analysis of protein localization in budding yeast.

Q99784	NOE1_HUMAN	Noelin	9039501	Identification and cloning of neuroblastoma-specific and nerve tissue-specific genes through compiled expression profiles.

P0ACY1	YDJA_ECOLI	Putative NAD(P)H nitroreductase ydjA	18241886	Crystal structure of a minimal nitroreductase, ydjA, from Escherichia coli K12 with and without FMN cofactor.

Q8IUH5	ZDH17_HUMAN	Palmitoyltransferase ZDHHC17	15603740	Huntingtin-interacting protein HIP14 is a palmitoyl transferase involved in palmitoylation and trafficking of multiple neuronal proteins.

Q9Z1N4	BPNT1_RAT	3'(2'),5'-bisphosphate nucleotidase 1	10347153	A novel mammalian lithium-sensitive enzyme with a dual enzymatic activity, 3'-phosphoadenosine 5'-phosphate phosphatase and inositol- polyphosphate 1-phosphatase.

Q95PZ0	CSN6_CAEEL	COP9 signalosome complex subunit 6	12781129	Neddylation and deneddylation of CUL-3 is required to target MEI- 1/katanin for degradation at the meiosis-to-mitosis transition in C. elegans.

Q96GN5	CDA7L_HUMAN	Cell division cycle-associated 7-like protein	15994933	Identification of a novel c-Myc protein interactor, JPO2, with transforming activity in medulloblastoma cells.

O14777	NDC80_HUMAN	Kinetochore protein NDC80 homolog	15961401	Architecture of the human Ndc80-Hec1 complex, a critical constituent of the outer kinetochore.

P48000	KNAT3_ARATH	Homeobox protein knotted-1-like 3	9161040	Localization of expression of KNAT3, a class 2 knotted1-like gene.

P40857	PHS1_YEAST	3-hydroxyacyl-CoA dehydratase PHS1	18272525	Membrane topology and essential amino acid residues of Phs1, a 3- hydroxyacyl-CoA dehydratase involved in very long-chain fatty acid elongation.

P39987	HSP7E_YEAST	Heat shock protein SSC3, mitochondrial	11150530	Ecm10, a novel hsp70 homolog in the mitochondrial matrix of the yeast Saccharomyces cerevisiae.

Q9UK80	UBP21_HUMAN	Ubiquitin carboxyl-terminal hydrolase 21	10786635	Sequencing, tissue distribution and chromosomal assignment of a novel ubiquitin-specific protease USP23.

Q54NP6	SNAA_DICDI	Alpha-soluble NSF attachment protein	10727946	Functional and molecular identification of novel members of the ubiquitous membrane fusion proteins alpha- and gamma-SNAP (soluble N- ethylmaleimide-sensitive factor-attachment proteins) families in Dictyostelium discoideum.

Q8K385	FRRS1_MOUSE	Ferric-chelate reductase 1	14499595	Stromal cell-derived receptor 2 and cytochrome b561 are functional ferric reductases.

Q38859	RPB11_ARATH	DNA-directed RNA polymerase II subunit RPB11	8617787	Association between 36- and 13.6-kDa alpha-like subunits of Arabidopsis thaliana RNA polymerase II.

Q6RYS9	DOPR3_CAEEL	Dopamine receptor 3	15378064	Mechanism of extrasynaptic dopamine signaling in Caenorhabditis elegans.

O60841	IF2P_HUMAN	Eukaryotic translation initiation factor 5B	10432305	Cloning and characterization of hIF2, a human homologue of bacterial translation initiation factor 2 and its interaction with HIV-1 matrix.

Q9Y7U7	SND1_SCHPO	Staphylococcal nuclease domain-containing protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8WXI4	ACO11_HUMAN	Acyl-coenzyme A thioesterase 11	11696000	BFIT, a unique acyl-CoA thioesterase induced in thermogenic brown adipose tissue: cloning, organization of the human gene and assessment of a potential link to obesity.

P53692	SMC6_SCHPO	Structural maintenance of chromosomes protein 6	15331764	Nse1, Nse2, and a novel subunit of the Smc5-Smc6 complex, Nse3, play a crucial role in meiosis.

Q13895	BYST_HUMAN	Bystin	9560222	A cytoplasmic protein, bystin, interacts with trophinin, tastin, and cytokeratin and may be involved in trophinin-mediated cell adhesion between trophoblast and endometrial epithelial cells.

Q8TAT5	NEIL3_HUMAN	Endonuclease 8-like 3	19170771	Human Nei-like protein NEIL3 has AP lyase activity specific for single-stranded DNA and confers oxidative stress resistance in Escherichia coli mutant.

O74969	GHT2_SCHPO	High-affinity glucose transporter ght2	10735857	Multiple hexose transporters of Schizosaccharomyces pombe.

Q9UUQ6	LCPS_RHIRA	Bifunctional enzyme CarRP	10951210	A bifunctional enzyme with lycopene cyclase and phytoene synthase activities is encoded by the carRP gene of Mucor circinelloides.

Q9P0K8	FOXJ2_HUMAN	Forkhead box protein J2	10777590	FHX, a novel fork head factor with a dual DNA binding specificity.

Q922I5	FOXI1_MOUSE	Forkhead box protein I1	12642503	Lack of pendrin expression leads to deafness and expansion of the endolymphatic compartment in inner ears of Foxi1 null mutant mice.

P08254	MMP3_HUMAN	Stromelysin-1	3360803	The complete primary structure of human matrix metalloproteinase-3. Identity with stromelysin.

Q07457	BRE1_YEAST	E3 ubiquitin-protein ligase BRE1	15632065	Histone H2B ubiquitylation is associated with elongating RNA polymerase II.

P05928	VPR_HV1BR	Protein Vpr	10620603	The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore.

P60756	MDGA2_RAT	MAM domain-containing glycosylphosphatidylinositol anchor protein 2	15019943	Identification and characterization of two novel brain-derived immunoglobulin superfamily members with a unique structural organization.

D3YN49	GEMC1_XENLA	Geminin coiled-coil domain-containing protein 1	20383140	GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication.

Q9UJW2	TINAG_HUMAN	Tubulointerstitial nephritis antigen	8770961	Receptors in proximal tubular epithelial cells for tubulointerstitial nephritis antigen.

P35134	UBC11_ARATH	Ubiquitin-conjugating enzyme E2 11	16339806	Genome analysis and functional characterization of the E2 and RING- type E3 ligase ubiquitination enzymes of Arabidopsis.

P20783	NTF3_HUMAN	Neurotrophin-3	7703225	Structure of the brain-derived neurotrophic factor/neurotrophin 3 heterodimer.

P14126	RL3_YEAST	60S ribosomal protein L3	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q941R4	GONS1_ARATH	GDP-mannose transporter	11595802	Identification and characterization of GONST1, a Golgi-localized GDP- mannose transporter in Arabidopsis.

P48961	CCND3_RAT	G1/S-specific cyclin-D3	7926809	Induction of D2 and D3 cyclin-encoding genes during promotion of the G1/S transition by prolactin in rat Nb2 cells.

Q86VB7	C163A_HUMAN	Scavenger receptor cysteine-rich type 1 protein M130	8370408	A new macrophage differentiation antigen which is a member of the scavenger receptor superfamily.

Q9DCP2	S38A3_MOUSE	Sodium-coupled neutral amino acid transporter 3	10716701	Identification and characterization of an amino acid transporter expressed differentially in liver.

A3KGV1	ODFP2_MOUSE	Outer dense fiber protein 2	9740324	Mouse Odf2 cDNAs consist of evolutionary conserved as well as highly variable sequences and encode outer dense fiber proteins of the sperm tail.

Q8LD49	TRXX_ARATH	Thioredoxin X, chloroplastic	19259774	A novel extended family of stromal thioredoxins.

P17050	NAGAB_HUMAN	Alpha-N-acetylgalactosaminidase	2174888	Human alpha-N-acetylgalactosaminidase-molecular cloning, nucleotide sequence, and expression of a full-length cDNA. Homology with human alpha-galactosidase A suggests evolution from a common ancestral gene.

Q16595	FRDA_HUMAN	Frataxin, mitochondrial	17468497	In vivo maturation of human frataxin.

P29353	SHC1_HUMAN	SHC-transforming protein 1	19172738	Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein.

Q9WVL5	MORC1_MOUSE	MORC family CW-type zinc finger protein 1	10369865	New gene family defined by MORC, a nuclear protein required for mouse spermatogenesis.

Q9P3U4	YKX2_SCHPO	Uncharacterized RING finger protein C328.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q61759	K1B21_MOUSE	Kallikrein 1-related peptidase b21	11606460	Mouse testicular Leydig cells express Klk21, a tissue kallikrein that cleaves fibronectin and IGF-binding protein-3.

Q9P7W5	RIO2_SCHPO	Serine/threonine-protein kinase rio2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P55042	RAD_HUMAN	GTP-binding protein RAD	18056528	Rad GTPase deficiency leads to cardiac hypertrophy.

P35439	NMDZ1_RAT	Glutamate [NMDA] receptor subunit zeta-1	16495444	A novel family of adhesion-like molecules that interacts with the NMDA receptor.

Q9JJ25	MEFV_RAT	Pyrin	10818206	Isolation, genomic organization, and expression analysis of the mouse and rat homologs of MEFV, the gene for familial Mediterranean fever.

Q05027	TAF9_YEAST	Transcription initiation factor TFIID subunit 9	10788514	Identification of two novel TAF subunits of the yeast Saccharomyces cerevisiae TFIID complex.

Q9UGP8	SEC63_HUMAN	Translocation protein SEC63 homolog	10799540	Mammalian Sec61 is associated with Sec62 and Sec63.

O22043	GGPP6_ARATH	Geranylgeranyl pyrophosphate synthase 6, mitochondrial	10759500	Five geranylgeranyl diphosphate synthases expressed in different organs are localized into three subcellular compartments in Arabidopsis.

Q04412	AGE1_YEAST	ADP-ribosylation factor GTPase-activating protein effector protein 1	14562095	Global analysis of protein localization in budding yeast.

Q06327	LOX1_ARATH	Lipoxygenase 1	7506426	An Arabidopsis thaliana lipoxygenase gene can be induced by pathogens, abscisic acid, and methyl jasmonate.

P33893	GATB_YEAST	Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial	8082172	PET112, a Saccharomyces cerevisiae nuclear gene required to maintain rho+ mitochondrial DNA.

O17403	CPSF2_CAEEL	Probable cleavage and polyadenylation specificity factor subunit 2	15790806	Functional genomic analysis of RNA interference in C. elegans.

P25847	MSH2_YEAST	DNA mismatch repair protein MSH2	9819445	Saccharomyces cerevisiae Msh2p and Msh6p ATPase activities are both required during mismatch repair.

P84387	XT1_XENTR	Antimicrobial peptide 1	11738090	Antimicrobial peptides isolated from skin secretions of the diploid frog, Xenopus tropicalis (Pipidae).

P30099	C11B2_RAT	Cytochrome P450 11B2, mitochondrial	8333830	Cloning and expression of a rat cytochrome P-450 11 beta- hydroxylase/aldosterone synthase (CYP11B2) cDNA variant.

P08937	OBP_RAT	Odorant-binding protein	3388043	Molecular cloning of odorant-binding protein: member of a ligand carrier family.

Q04080	GPI17_YEAST	GPI transamidase component GPI17	11483512	PIG-S and PIG-T, essential for GPI anchor attachment to proteins, form a complex with GAA1 and GPI8.

Q804H7	BI52B_XENLA	Baculoviral IAP repeat-containing protein 5.2-B	12535669	Molecular cloning and characterization of a novel inhibitor of apoptosis protein from Xenopus laevis.

Q12089	AEP3_YEAST	ATPase expression protein 3	14742425	Aep3p stabilizes the mitochondrial bicistronic mRNA encoding subunits 6 and 8 of the H+-translocating ATP synthase of Saccharomyces cerevisiae.

P31317	OTC_SCHPO	Ornithine carbamoyltransferase, mitochondrial	1313366	Cloning and sequencing of arg3 and arg11 genes of Schizosaccharomyces pombe on a 10-kb DNA fragment. Heterologous expression and mitochondrial targeting of their translation products.

P28370	SMCA1_HUMAN	Probable global transcription activator SNF2L1	1408766	Cloning of human and bovine homologs of SNF2/SWI2: a global activator of transcription in yeast S. cerevisiae.

P24886	NU4LM_CAEEL	NADH-ubiquinone oxidoreductase chain 4L	1551572	The mitochondrial genomes of two nematodes, Caenorhabditis elegans and Ascaris suum.

Q9Y7U4	NSE3_SCHPO	Non-structural maintenance of chromosome element 3	15601840	Composition and architecture of the Schizosaccharomyces pombe Rad18 (Smc5-6) complex.

P54783	ALO_YEAST	D-arabinono-1,4-lactone oxidase	10094636	D-erythroascorbic acid is an important antioxidant molecule in Saccharomyces cerevisiae.

P41831	KPR1_SCHPO	Ribose-phosphate pyrophosphokinase 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12461	PTPA2_YEAST	Serine/threonine-protein phosphatase 2A activator 2	16380387	The protein phosphatase 2A phosphatase activator is a novel peptidyl- prolyl cis/trans-isomerase.

P38993	FET3_YEAST	Iron transport multicopper oxidase FET3	8293473	The FET3 gene of S. cerevisiae encodes a multicopper oxidase required for ferrous iron uptake.

P39404	BGLJ_ECOLI	Transcriptional activator protein BglJ	8725214	A mutation in a new gene, bglJ, activates the bgl operon in Escherichia coli K-12.

Q06324	MMR1_YEAST	Mitochondrial MYO2 receptor-related protein 1	13679573	Widespread cytoplasmic mRNA transport in yeast: identification of 22 bud-localized transcripts using DNA microarray analysis.

O14201	MUG86_SCHPO	Meiotically up-regulated gene 86 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q6DGD3	SV91A_DANRE	Histone-lysine N-methyltransferase SUV39H1-A	16980612	Zebra fish Dnmt1 and Suv39h1 regulate organ-specific terminal differentiation during development.

Q03713	AIM31_YEAST	Altered inheritance of mitochondria protein 31, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

Q12009	TRMB_YEAST	tRNA (guanine-N(7)-)-methyltransferase	14562095	Global analysis of protein localization in budding yeast.

Q08012	DRK_DROME	Protein enhancer of sevenless 2B	12128212	SH3 domain-mediated binding of the Drk protein to Dos is an important step in signaling of Drosophila receptor tyrosine kinases.

Q9VT52	INSL3_DROME	Probable insulin-like peptide 3	11250149	An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control.

O14641	DVL2_HUMAN	Segment polarity protein dishevelled homolog DVL-2	9192851	Human dishevelled genes constitute a DHR-containing multigene family.

P09758	TACD2_HUMAN	Tumor-associated calcium signal transducer 2	8382772	Retroposition in a family of carcinoma-associated antigen genes.

Q54PV8	IPYR_DICDI	Inorganic pyrophosphatase	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P29349	CSW_DROME	Tyrosine-protein phosphatase corkscrew	8948575	The nonreceptor protein tyrosine phosphatase corkscrew functions in multiple receptor tyrosine kinase pathways in Drosophila.

Q9UPT5	EXOC7_HUMAN	Exocyst complex component 7	16148947	Rab11-FIP3 and FIP4 interact with Arf6 and the exocyst to control membrane traffic in cytokinesis.

Q9Y265	RUVB1_HUMAN	RuvB-like 1	14966270	Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans.

Q9QZH6	ECSIT_MOUSE	Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial	10465784	ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway.

A0AVT1	UBA6_HUMAN	Ubiquitin-like modifier-activating enzyme 6	17889673	E1-L2 activates both ubiquitin and FAT10.

O00571	DDX3X_HUMAN	ATP-dependent RNA helicase DDX3X	9381176	Functional coherence of the human Y chromosome.

Q9NYJ8	TAB2_HUMAN	TGF-beta-activated kinase 1 and MAP3K7-binding protein 2	11460167	TAK1 is a ubiquitin-dependent kinase of MKK and IKK.

P32634	PMD1_YEAST	Negative regulator of sporulation PMD1	9383076	Identification of a new class of negative regulators affecting sporulation-specific gene expression in yeast.

Q92769	HDAC2_HUMAN	Histone deacetylase 2	19182791	Chfr is linked to tumour metastasis through the downregulation of HDAC1.

P21128	ENDOU_HUMAN	Poly(U)-specific endoribonuclease	18936097	The tumor marker human placental protein 11 is an endoribonuclease.

P86097	NXS3_MICSU	Short neurotoxin MS3	18384102	Proteomic analysis of the venom from the fish eating coral snake Micrurus surinamensis: novel toxins, their function and phylogeny.

Q9NQR1	SETD8_HUMAN	Histone-lysine N-methyltransferase SETD8	15933069	Specificity and mechanism of the histone methyltransferase Pr-Set7.

P33754	SEC66_YEAST	Translocation protein SEC66	7758110	Posttranslational protein transport in yeast reconstituted with a purified complex of Sec proteins and Kar2p.

P38919	IF4A3_HUMAN	Eukaryotic initiation factor 4A-III	18423201	SKAR links pre-mRNA splicing to mTOR/S6K1-mediated enhanced translation efficiency of spliced mRNAs.

P13611	CSPG2_HUMAN	Versican core protein	7528742	Characterization of the complete genomic structure of the human versican gene and functional analysis of its promoter.

Q9CR95	NECP1_MOUSE	Adaptin ear-binding coat-associated protein 1	14555962	Identification of a family of endocytic proteins that define a new alpha-adaptin ear-binding motif.

P05219	TBB_SCHPO	Tubulin beta chain	6094012	The NDA3 gene of fission yeast encodes beta-tubulin: a cold-sensitive nda3 mutation reversibly blocks spindle formation and chromosome movement in mitosis.

P20795	VPS33_YEAST	Vacuolar protein sorting-associated protein 33	12553664	A novel phospholipid-binding protein from the yeast Saccharomyces cerevisiae with dual binding specificities for the transport GTPase Ypt7p and the Sec1-related Vps33p.

O13764	PEX6_SCHPO	Peroxisomal ATPase pex6	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q04739	GAL83_YEAST	SNF1 protein kinase subunit beta-3	10990457	beta-subunits of Snf1 kinase are required for kinase function and substrate definition.

Q6NUQ1	RINT1_HUMAN	RAD50-interacting protein 1	11096100	RINT-1, a novel Rad50-interacting protein, participates in radiation- induced G2/M checkpoint control.

P67965	VEGFA_COTJA	Vascular endothelial growth factor A	7556923	Overexpression of vascular endothelial growth factor in the avian embryo induces hypervascularization and increased vascular permeability without alterations of embryonic pattern formation.

P11309	PIM1_HUMAN	Proto-oncogene serine/threonine-protein kinase pim-1	1825810	The pim-1 oncogene encodes two related protein-serine/threonine kinases by alternative initiation at AUG and CUG.

P27008	PARP1_RAT	Poly [ADP-ribose] polymerase 1	9385436	Isolation of cDNA encoding full-length rat (Rattus norvegicus) poly (ADP-ribose) polymerase.

Q9FJH6	AB1F_ARATH	ABC transporter F family member 1	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P43080	GUC1A_HUMAN	Guanylyl cyclase-activating protein 1	7983048	Molecular characterization of human and mouse photoreceptor guanylate cyclase-activating protein (GCAP) and chromosomal localization of the human gene.

P97927	LAMA4_MOUSE	Laminin subunit alpha-4	9346933	Primary structure, developmental expression, and immunolocalization of the murine laminin alpha4 chain.

Q4WZ11	IELA_ASPFU	Elastase inhibitor AFUEI	18566136	Biochemical properties and primary structure of elastase inhibitor AFUEI from Aspergillus fumigatus.

Q02785	PDR12_YEAST	ATP-dependent permease PDR12	10419965	The Saccharomyces cerevisiae weak-acid-inducible ABC transporter Pdr12 transports fluorescein and preservative anions from the cytosol by an energy-dependent mechanism.

Q9UTG8	DAD2_SCHPO	DASH complex subunit dad2	16079914	Molecular analysis of kinetochore architecture in fission yeast.

Q9XTT4	ANI1_CAEEL	Anillin-like protein 1	15930113	Distinct roles for two C. elegans anillins in the gonad and early embryo.

P84777	KA156_TITDI	Potassium channel toxin alpha-KTx 15.6	15369825	Discrepin, a new peptide of the sub-family alpha-ktx15, isolated from the scorpion Tityus discrepans irreversibly blocks K+ -channels (IA currents) of cerebellum granular cells.

Q86Y01	DTX1_HUMAN	Protein deltex-1	11564735	Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor.

Q94CD8	E134_ARATH	Glucan endo-1,3-beta-glucosidase 4	12805588	Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis.

Q9UL03	INT6_HUMAN	Integrator complex subunit 6	10467397	Isolation of DICE1: a gene frequently affected by LOH and downregulated in lung carcinomas.

P97536	CAND1_RAT	Cullin-associated NEDD8-dissociated protein 1	8954946	Molecular cloning of a novel 120-kDa TBP-interacting protein.

Q9M246	TIF3A_ARATH	Protein TIFY 3A	20360743	NINJA connects the co-repressor TOPLESS to jasmonate signalling.

P38812	GEP4_YEAST	Phosphatidylglycerophosphatase GEP4, mitochondrial	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

P48802	FGF3_DANRE	Fibroblast growth factor 3	8622866	Secretion and mitogenic activity of zebrafish FGF3 reveal intermediate properties relative to mouse and Xenopus homologues.

Q9Y3V2	RWDD3_HUMAN	RWD domain-containing protein 3	17956732	RSUME, a small RWD-containing protein, enhances SUMO conjugation and stabilizes HIF-1alpha during hypoxia.

P29674	LHX1_XENLA	LIM/homeobox protein Lhx1	10491256	Synergism between Pax-8 and lim-1 in embryonic kidney development.

O94827	PKHG5_HUMAN	Pleckstrin homology domain-containing family G member 5	12761501	Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.

P28861	FENR_ECOLI	Ferredoxin--NADP reductase	2834327	Isolation and characterization of methyl viologen-sensitive mutants of Escherichia coli K-12.

Q9LXV2	MYB46_ARATH	Transcription factor MYB46	17890373	The MYB46 transcription factor is a direct target of SND1 and regulates secondary wall biosynthesis in Arabidopsis.

Q03954	SPC19_YEAST	DASH complex subunit SPC19	11799062	The mitotic spindle is required for loading of the DASH complex onto the kinetochore.

Q6BDR8	NSE4_SCHPO	Non-structural maintenance of chromosome element 4	16478984	The Nse5-Nse6 dimer mediates DNA repair roles of the Smc5-Smc6 complex.

P26587	TIP31_ARATH	Aquaporin TIP3-1	16668923	Vegetative and seed-specific forms of tonoplast intrinsic protein in the vacuolar membrane of Arabidopsis thaliana.

P32336	NUD1_YEAST	Protein NUD1	11742972	Prospore membrane formation linked to the leading edge protein (LEP) coat assembly.

Q9GZS9	CHST5_HUMAN	Carbohydrate sulfotransferase 5	12218059	Enzymatic synthesis in vitro of the disulfated disaccharide unit of corneal keratan sulfate.

Q02936	HH_DROME	Protein hedgehog	1280560	Molecular organization and embryonic expression of the hedgehog gene involved in cell-cell communication in segmental patterning of Drosophila.

Q8N6T7	SIRT6_HUMAN	NAD-dependent deacetylase sirtuin-6	16079181	Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins.

P53070	MTO1_YEAST	Mitochondrial translation optimization protein 1	9774408	MTO1 codes for a mitochondrial protein required for respiration in paromomycin-resistant mutants of Saccharomyces cerevisiae.

P92937	CIPKF_ARATH	CBL-interacting serine/threonine-protein kinase 15	12194854	A calcium sensor and its interacting protein kinase are global regulators of abscisic acid signaling in Arabidopsis.

Q9UT82	RT06_SCHPO	37S ribosomal protein MRP17, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O14122	CUL4_SCHPO	Cullin-4	16024659	A Rik1-associated, cullin-dependent E3 ubiquitin ligase is essential for heterochromatin formation.

Q9BXM0	PRAX_HUMAN	Periaxin	11133365	Periaxin mutations cause recessive Dejerine-Sottas neuropathy.

Q04658	SMA2_YEAST	Spore membrane assembly protein 2	17298976	Erv14 family cargo receptors are necessary for ER exit during sporulation in Saccharomyces cerevisiae.

P20023	CR2_HUMAN	Complement receptor type 2	2563370	Genomic organization and polymorphisms of the human C3d/Epstein-Barr virus receptor.

P51151	RAB9A_HUMAN	Ras-related protein Rab-9A	18243103	Rab and Arl GTPase family members cooperate in the localization of the golgin GCC185.

Q26365	ADT_DROME	ADP,ATP carrier protein	7520869	Molecular analysis of a candidate gene for the reproductive isolation between sibling species of Drosophila.

P49146	NPY2R_HUMAN	Neuropeptide Y receptor type 2	7559383	Cloning and functional expression of a cDNA encoding a human type 2 neuropeptide Y receptor.

Q9UUF3	YNF3_SCHPO	Probable tyrosine-protein phosphatase C17A3.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UNG2	TNF18_HUMAN	Tumor necrosis factor ligand superfamily member 18	10074428	Identification of a new member of the tumor necrosis factor family and its receptor, a human ortholog of mouse GITR.

P51161	FABP6_HUMAN	Gastrotropin	7588781	Molecular cloning, expression, and characterization of a human intestinal 15-kDa protein.

P56202	CATW_HUMAN	Cathepsin W	9823953	Lymphopain, a cytotoxic T and natural killer cell-associated cysteine proteinase.

P27882	ERV1_YEAST	Mitochondrial FAD-linked sulfhydryl oxidase ERV1	16181637	The essential mitochondrial protein Erv1 cooperates with Mia40 in biogenesis of intermembrane space proteins.

Q39057	CONS_ARATH	Zinc finger protein CONSTANS	11323677	CONSTANS mediates between the circadian clock and the control of flowering in Arabidopsis.

P47064	AP3S_YEAST	AP-3 complex subunit sigma	9335339	The AP-3 adaptor complex is essential for cargo-selective transport to the yeast vacuole.

O15130	NPFF_HUMAN	FMRFamide-related peptides	9224703	A human gene encoding morphine modulating peptides related to NPFF and FMRFamide.

P48582	BRO1_YEAST	Vacuolar-sorting protein BRO1	14523026	Permease recycling and ubiquitination status reveal a particular role for Bro1 in the multivesicular body pathway.

Q9WVB1	RAB6A_RAT	Ras-related protein Rab-6A	11062069	Identification of Rab6 as an N-ethylmaleimide-sensitive fusion protein-binding protein.

Q9Y7Z8	MYO1_SCHPO	Myosin-1	11076964	Fission yeast myosin-I, Myo1p, stimulates actin assembly by Arp2/3 complex and shares functions with WASp.

Q15198	PGFRL_HUMAN	Platelet-derived growth factor receptor-like protein	7898930	Isolation of a candidate tumor suppressor gene on chromosome 8p21.3- p22 that is homologous to an extracellular domain of the PDGF receptor beta gene.

Q9LHS7	GPAT7_ARATH	Glycerol-3-phosphate acyltransferase 7	12897259	Arabidopsis AtGPAT1, a member of the membrane-bound glycerol-3- phosphate acyltransferase gene family, is essential for tapetum differentiation and male fertility.

Q78EG7	TP4A1_RAT	Protein tyrosine phosphatase type IVA 1	8196618	PRL-1, a unique nuclear protein tyrosine phosphatase, affects cell growth.

Q5AX45	RGLA_EMENI	Rhamnogalacturonate lyase A	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

Q9PSM4	LECG_LACST	Galactose-specific lectin	3671807	Purification and some properties of hemagglutinating protein mutina from bushmaster Lachesis muta snake venom.

Q9VGH1	CP315_DROME	Cytochrome P450 315a1, mitochondrial	12177427	Molecular and biochemical characterization of two P450 enzymes in the ecdysteroidogenic pathway of Drosophila melanogaster.

Q925T6	GRIP1_MOUSE	Glutamate receptor-interacting protein 1	9883737	PDZ proteins bind, cluster, and synaptically colocalize with Eph receptors and their ephrin ligands.

P07262	DHE4_YEAST	NADP-specific glutamate dehydrogenase 1	2989290	Nucleotide sequence of yeast GDH1 encoding nicotinamide adenine dinucleotide phosphate-dependent glutamate dehydrogenase.

Q96QU8	XPO6_HUMAN	Exportin-6	14592989	Exportin 6: a novel nuclear export receptor that is specific for profilin.actin complexes.

Q06162	NKP2_YEAST	Central kinetochore subunit NKP2	12408861	Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase Ipl1p.

Q13618	CUL3_HUMAN	Cullin-3	9733711	Cloning and expression analysis of a novel salicylate suppressible gene, Hs-CUL-3, a member of cullin/Cdc53 family.

Q8BMQ3	BNC2_MOUSE	Zinc finger protein basonuclin-2	15081112	Identification of Basonuclin2, a DNA-binding zinc-finger protein expressed in germ tissues and skin keratinocytes.

Q8K3X6	ANS4B_MOUSE	Ankyrin repeat and SAM domain-containing protein 4B	15461667	Harp (harmonin-interacting, ankyrin repeat-containing protein), a novel protein that interacts with harmonin in epithelial tissues.

Q07533	CYK3_YEAST	Cytokinesis protein 3	14562095	Global analysis of protein localization in budding yeast.

Q09925	LCB2_SCHPO	Serine palmitoyltransferase 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q54LX0	CBPM_DICDI	Calcium-binding protein M	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P0ABG4	FTSW_ECOLI	Cell division protein ftsW	9006034	Two polypeptide products of the Escherichia coli cell division gene ftsW and a possible role for FtsW in FtsZ function.

Q7DNA1	CHI2_ORYSJ	Chitinase 2	18323646	Purification and characterization of a rice class I chitinase, OsChia1b, produced in Esherichia coli.

O15945	ARNT_DROME	Aryl hydrocarbon receptor nuclear translocator homolog	9409674	The Drosophila tango gene encodes a bHLH-PAS protein that is orthologous to mammalian Arnt and controls CNS midline and tracheal development.

Q9D1T0	LIGO1_MOUSE	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1	17726113	Inhibition of the leucine-rich repeat protein LINGO-1 enhances survival, structure, and function of dopaminergic neurons in Parkinson's disease models.

P61077	UB2D3_HUMAN	Ubiquitin-conjugating enzyme E2 D3	20347421	Priming and extending: a UbcH5/Cdc34 E2 handoff mechanism for polyubiquitination on a SCF substrate.

Q13478	IL18R_HUMAN	Interleukin-18 receptor 1	9325300	Purification and characterization of the human interleukin-18 receptor.

O55137	ACOT1_MOUSE	Acyl-coenzyme A thioesterase 1	11694534	The peroxisome proliferator-induced cytosolic type I acyl-CoA thioesterase (CTE-I) is a serine-histidine-aspartic acid alpha /beta hydrolase.

P48483	PP13_ARATH	Serine/threonine-protein phosphatase PP1 isozyme 3	7678768	Expression of multiple type 1 phosphoprotein phosphatases in Arabidopsis thaliana.

O00291	HIP1_HUMAN	Huntingtin-interacting protein 1	11889126	HIP1 and HIP12 display differential binding to F-actin, AP2, and clathrin. Identification of a novel interaction with clathrin light chain.

P48974	V1BR_RAT	Vasopressin V1b receptor	7624319	Extrapituitary expression of the rat V1b vasopressin receptor gene.

P67775	PP2AA_HUMAN	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform	17245430	A specific PP2A regulatory subunit, B56gamma, mediates DNA damage- induced dephosphorylation of p53 at Thr55.

Q08972	NEW1_YEAST	[NU+] prion formation protein 1	14562095	Global analysis of protein localization in budding yeast.

Q9UIS9	MBD1_HUMAN	Methyl-CpG-binding domain protein 1	19666599	Human BAHD1 promotes heterochromatic gene silencing.

Q61810	LTBP3_MOUSE	Latent-transforming growth factor beta-binding protein 3	7730318	Isolation of a novel latent transforming growth factor-beta binding protein gene (LTBP-3).

Q11203	SIAT6_HUMAN	CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase	8333853	Cloning and expression of human Gal beta 1,3(4)GlcNAc alpha 2,3- sialyltransferase.

Q8IUK5	PXDC1_HUMAN	Plexin domain-containing protein 1	10947988	Genes expressed in human tumor endothelium.

Q9XFI1	TRL12_ARATH	Thioredoxin-like 1-2, chloroplastic	19109414	A small family of chloroplast atypical thioredoxins.

Q8TD57	DYH3_HUMAN	Dynein heavy chain 3, axonemal	9256245	Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.

P20491	FCERG_MOUSE	High affinity immunoglobulin epsilon receptor subunit gamma	2527850	Complete structure of the mouse mast cell receptor for IgE (Fc epsilon RI) and surface expression of chimeric receptors (rat-mouse- human) on transfected cells.

Q86Y38	XYLT1_HUMAN	Xylosyltransferase 1	11099377	Molecular cloning and expression of human UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase and its first isoform XT-II.

Q06505	IWS1_YEAST	Transcription factor IWS1	12242279	RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach.

P32467	HXT4_YEAST	Low-affinity glucose transporter HXT4	17180689	Xylose transport studies with xylose-utilizing Saccharomyces cerevisiae strains expressing heterologous and homologous permeases.

Q91903	ELAV2_XENLA	ELAV-like protein 2	19458392	Participation of Xenopus Elr-type proteins in vegetal mRNA localization during oogenesis.

O13747	EPT1_SCHPO	RING finger protein ETP1 homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P30793	GCH1_HUMAN	GTP cyclohydrolase 1	14717702	GTP cyclohydrolase I utilizes metal-free GTP as its substrate.

P14902	I23O1_HUMAN	Indoleamine 2,3-dioxygenase 1	16477023	Crystal structure of human indoleamine 2,3-dioxygenase: catalytic mechanism of O2 incorporation by a heme-containing dioxygenase.

Q9ERH6	MOAP1_MOUSE	Modulator of apoptosis 1	17404571	RASSF6 is a novel member of the RASSF family of tumor suppressors.

P53725	MPP6_YEAST	M-phase phosphoprotein 6 homolog	14562095	Global analysis of protein localization in budding yeast.

P15529	MCP_HUMAN	Membrane cofactor protein	8402913	The human CD46 molecule is a receptor for measles virus (Edmonston strain).

Q96P70	IPO9_HUMAN	Importin-9	11823430	Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains.

P40161	RT106_YEAST	Histone chaperone RTT106	14562095	Global analysis of protein localization in budding yeast.

O60248	SOX15_HUMAN	Protein SOX-15	9540826	Isolation and expression of a human SRY-related cDNA hSOX20.

Q9H239	MMP28_HUMAN	Matrix metalloproteinase-28	11255011	MMP-28, a new human matrix metalloproteinase with an unusual cysteine-switch sequence is widely expressed in tumors.

Q3KQ35	S17AA_XENLA	Transcription factor Sox-17-alpha-A	12798301	VegT induces endoderm by a self-limiting mechanism and by changing the competence of cells to respond to TGF-beta signals.

Q920G9	GMCL1_MOUSE	Germ cell-less protein-like 1	11591818	Nuclear membrane protein LAP2beta mediates transcriptional repression alone and together with its binding partner GCL (germ-cell-less).

Q8CF82	ABCA5_RAT	ATP-binding cassette sub-family A member 5	16162093	Subcellular localization of rat Abca5, a rat ATP-binding-cassette transporter expressed in Leydig cells, and characterization of its splice variant apparently encoding a half-transporter.

O77059	CRY1_DROME	Cryptochrome-1	9845369	CRY, a Drosophila clock and light-regulated cryptochrome, is a major contributor to circadian rhythm resetting and photosensitivity.

O18209	PMY13_CAEEL	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase wee-1.3	16466390	Cell cycle control by daf-21/Hsp90 at the first meiotic prophase/metaphase boundary during oogenesis in Caenorhabditis elegans.

Q15166	PON3_HUMAN	Serum paraoxonase/lactonase 3	8661009	The human serum paraoxonase/arylesterase gene (PON1) is one member of a multigene family.

Q9GM70	ST17A_RABIT	Serine/threonine-protein kinase 17A	11279167	rDRAK1, a novel kinase related to apoptosis, is strongly expressed in active osteoclasts and induces apoptosis.

P08155	KRUH_DROME	Krueppel homologous protein 1	10772791	Kruppel-homolog, a stage-specific modulator of the prepupal ecdysone response, is essential for Drosophila metamorphosis.

P41968	MC3R_HUMAN	Melanocortin receptor 3	8463333	Molecular cloning of a novel melanocortin receptor.

P25189	MYP0_HUMAN	Myelin protein P0	7693129	Charcot-Marie-Tooth neuropathy type 1B is associated with mutations of the myelin P0 gene.

Q14393	GAS6_HUMAN	Growth arrest-specific protein 6	8336730	The protein encoded by a growth arrest-specific gene (gas6) is a new member of the vitamin K-dependent proteins related to protein S, a negative coregulator in the blood coagulation cascade.

Q10099	SEH1_SCHPO	Nucleoporin seh1	15226438	The fission yeast Nup107-120 complex functionally interacts with the small GTPase Ran/Spi1 and is required for mRNA export, nuclear pore distribution, and proper cell division.

Q91713	CHRD_XENLA	Chordin	18775317	Robust stability of the embryonic axial pattern requires a secreted scaffold for chordin degradation.

P47011	GLG2_YEAST	Glycogenin-2	14562095	Global analysis of protein localization in budding yeast.

Q14966	ZN638_HUMAN	Zinc finger protein 638	8647861	A large DNA-binding nuclear protein with RNA recognition motif and serine/arginine-rich domain.

O81283	TC159_ARATH	Translocase of chloroplast 159, chloroplastic	10646606	The major protein import receptor of plastids is essential for chloroplast biogenesis.

Q92851	CASPA_HUMAN	Caspase-10	8755496	In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains.

Q13542	4EBP2_HUMAN	Eukaryotic translation initiation factor 4E-binding protein 2	7935836	Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function.

Q5UE94	TBPL2_XENLA	TATA box-binding protein-like protein 2	15345743	Specialized and redundant roles of TBP and a vertebrate-specific TBP paralog in embryonic gene regulation in Xenopus.

Q54ES9	TCPB_DICDI	T-complex protein 1 subunit beta	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q13671	RIN1_HUMAN	Ras and Rab interactor 1	7862125	A human protein selected for interference with Ras function interacts directly with Ras and competes with Raf1.

P11632	NHP6A_YEAST	Non-histone chromosomal protein 6A	9468494	Determinants of DNA binding and bending by the Saccharomyces cerevisiae high mobility group protein NHP6A that are important for its biological activities. Role of the unique N terminus and putative intercalating methionine.

Q07930	PML1_YEAST	Pre-mRNA leakage protein 1	14562095	Global analysis of protein localization in budding yeast.

Q9SE97	FH1_ARATH	Formin-like protein 1	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

O74499	LSM7_SCHPO	U6 snRNA-associated Sm-like protein LSm7	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9C5J8	OEP80_ARATH	Outer envelope protein of 80 kDa, chloroplastic	16618929	Mapping the Arabidopsis organelle proteome.

P31644	GBRA5_HUMAN	Gamma-aminobutyric acid receptor subunit alpha-5	1321750	Cloning and expression of a cDNA encoding the human GABA-A receptor alpha 5 subunit.

Q86H13	PDE4_DICDI	cAMP-specific 3',5'-cAMP phosphodiesterase 4	16644729	DdPDE4, a novel cAMP-specific phosphodiesterase at the surface of dictyostelium cells.

Q9Y2T6	GPR55_HUMAN	G-protein coupled receptor 55	19723626	Atypical responsiveness of the orphan receptor GPR55 to cannabinoid ligands.

O18158	OGT1_CAEEL	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase	9083068	O-linked GlcNAc transferase is a conserved nucleocytoplasmic protein containing tetratricopeptide repeats.

P22466	GALA_HUMAN	Galanin	1370155	Sequence of human galanin and its inhibition of glucose-stimulated insulin secretion from RIN cells.

Q9H6D7	HAUS4_HUMAN	HAUS augmin-like complex subunit 4	19427217	HAUS, the 8-subunit human augmin complex, regulates centrosome and spindle integrity.

P25369	LSB5_YEAST	LAS seventeen-binding protein 5	10512884	The Saccharomyces cerevisiae homologue of human Wiskott-Aldrich syndrome protein Las17p interacts with the Arp2/3 complex.

Q9P6J8	YHD2_SCHPO	Uncharacterized deaminase C1683.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NR71	ASAH2_HUMAN	Neutral ceramidase	10781606	Molecular cloning and characterization of a human mitochondrial ceramidase.

Q9BZD6	TMG4_HUMAN	Transmembrane gamma-carboxyglutamic acid protein 4	11171957	Identification of two novel transmembrane gamma-carboxyglutamic acid proteins expressed broadly in fetal and adult tissues.

Q9JI51	VTI1A_RAT	Vesicle transport through interaction with t-SNAREs homolog 1A	10908612	The SNARE Vti1a-beta is localized to small synaptic vesicles and participates in a novel SNARE complex.

Q9LMM0	GPAT4_ARATH	Glycerol-3-phosphate acyltransferase 4	12897259	Arabidopsis AtGPAT1, a member of the membrane-bound glycerol-3- phosphate acyltransferase gene family, is essential for tapetum differentiation and male fertility.

Q9Y2B2	PIGL_HUMAN	N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase	10085243	Mammalian PIG-L and its yeast homologue Gpi12p are N- acetylglucosaminylphosphatidylinositol de-N-acetylases essential in glycosylphosphatidylinositol biosynthesis.

Q12104	SWT1_YEAST	Transcriptional protein SWT1	17030511	Swt1, a novel yeast protein, functions in transcription.

O24407	IAA16_ARATH	Auxin-responsive protein IAA16	12036262	Genetics of Aux/IAA and ARF action in plant growth and development.

Q9SU29	UPL5_ARATH	E3 ubiquitin-protein ligase UPL5	20409006	A HECT E3 ubiquitin ligase negatively regulates Arabidopsis leaf senescence through degradation of the transcription factor WRKY53.

O08957	NRN1_RAT	Neuritin	9122250	Neuritin: a gene induced by neural activity and neurotrophins that promotes neuritogenesis.

P53226	BUD9_YEAST	Bud site selection protein 9	8657162	Genetic analysis of the bipolar pattern of bud site selection in the yeast Saccharomyces cerevisiae.

Q8R191	SNG3_MOUSE	Synaptogyrin-3	14755516	Characterization of synaptogyrin 3 as a new synaptic vesicle protein.

O14788	TNF11_HUMAN	Tumor necrosis factor ligand superfamily member 11	10708588	Cancer cells responsible for humoral hypercalcemia express mRNA encoding a secreted form of ODF/TRANCE that induces osteoclast formation.

P69781	GAT12_ARATH	GATA transcription factor 12	17208962	Conservation, convergence, and divergence of light-responsive, circadian-regulated, and tissue-specific expression patterns during evolution of the Arabidopsis GATA gene family.

Q800K6	TOB1A_XENLA	DNA topoisomerase 2-binding protein 1-A	20383140	GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication.

O42173	PV1_XENLA	Homeobox protein pv.1	10191050	Opposite effects of FGF and BMP-4 on embryonic blood formation: roles of PV.1 and GATA-2.

P54259	ATN1_HUMAN	Atrophin-1	10814707	Protein binding of a DRPLA family through arginine-glutamic acid dipeptide repeats is enhanced by extended polyglutamine.

Q92915	FGF14_HUMAN	Fibroblast growth factor 14	8790420	Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development.

Q7L523	RRAGA_HUMAN	Ras-related GTP-binding protein A	14660641	A novel human nucleolar protein, Nop132, binds to the G proteins, RRAG A/C/D.

Q6QI06	RICTR_MOUSE	Rapamycin-insensitive companion of mTOR	16962653	SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity.

O13898	PMT1_SCHPO	Dolichyl-phosphate-mannose--protein mannosyltransferase 1	15948957	Protein O-mannosylation is crucial for cell wall integrity, septation and viability in fission yeast.

Q9H668	STN1_HUMAN	CST complex subunit STN1	19648609	OB fold-containing protein 1 (OBFC1), a human homolog of yeast Stn1, associates with TPP1 and is implicated in telomere length regulation.

P57082	TBX4_HUMAN	T-box transcription factor TBX4	15106123	Mutations in the human TBX4 gene cause small patella syndrome.

Q96T58	MINT_HUMAN	Msx2-interacting protein	16129689	Interaction of the Epstein-Barr virus mRNA export factor EB2 with human Spen proteins SHARP, OTT1, and a novel member of the family, OTT3, links Spen proteins with splicing regulation and mRNA export.

P33311	MDL2_YEAST	ATP-dependent permease MDL2, mitochondrial	11251115	Role of the ABC transporter Mdl1 in peptide export from mitochondria.

P30839	AL3A2_RAT	Fatty aldehyde dehydrogenase	1717467	Molecular cloning, sequencing, and expression of cDNA for rat liver microsomal aldehyde dehydrogenase.

P56388	CART_MOUSE	Cocaine- and amphetamine-regulated transcript protein	10612705	CART: from gene to function.

Q92781	RDH1_HUMAN	11-cis retinol dehydrogenase	10369264	Mutations in the gene encoding 11-cis retinol dehydrogenase cause delayed dark adaptation and fundus albipunctatus.

Q9M7Q4	AI5L5_ARATH	ABSCISIC ACID-INSENSITIVE 5-like protein 5	16284313	AREB1 is a transcription activator of novel ABRE-dependent ABA signaling that enhances drought stress tolerance in Arabidopsis.

P75906	PGAB_ECOLI	Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase	18359807	Roles of pgaABCD genes in synthesis, modification, and export of the Escherichia coli biofilm adhesin poly-beta-1,6-N-acetyl-D- glucosamine.

Q8BMW7	NIPA3_MOUSE	Magnesium transporter NIPA3	18667602	Functional characterization of NIPA2, a selective Mg2+ transporter.

Q76MJ5	ERN2_HUMAN	Serine/threonine-protein kinase/endoribonuclease IRE2	11175748	Tranlational control by the ER transmembrane kinase/ribonuclease IRE1 under ER stress.

P53289	YG3S_YEAST	Uncharacterized protein RTS3	14562095	Global analysis of protein localization in budding yeast.

P11672	NGAL_MOUSE	Neutrophil gelatinase-associated lipocalin	2542864	SV40-induced expression of mouse gene 24p3 involves a post- transcriptional mechanism.

P84997	MYG_BUBBU	Myoglobin	16959515	Characterization and kinetics studies of water buffalo (Bubalus bubalis) myoglobin.

Q16849	PTPRN_HUMAN	Receptor-type tyrosine-protein phosphatase-like N	18048354	Structure of the mature ectodomain of the human receptor-type protein-tyrosine phosphatase IA-2.

P90859	HRDL1_CAEEL	E3 ubiquitin-protein ligase hrd-like protein 1	17825049	ER E3 ubiquitin ligase HRD-1 and its specific partner chaperone BiP play important roles in ERAD and developmental growth in Caenorhabditis elegans.

O13998	YEI3_SCHPO	Uncharacterized GTP-binding protein C27E2.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P32497	EIF3C_YEAST	Eukaryotic translation initiation factor 3 subunit C	9671501	Identification of a translation initiation factor 3 (eIF3) core complex, conserved in yeast and mammals, that interacts with eIF5.

P30624	LCF1_YEAST	Long-chain-fatty-acid--CoA ligase 1	8206942	Biochemical studies of three Saccharomyces cerevisiae acyl-CoA synthetases, Faa1p, Faa2p, and Faa3p.

Q92212	STE20_CANAL	Serine/threonine-protein kinase CST20	8917572	Candida albicans strains heterozygous and homozygous for mutations in mitogen-activated protein kinase signaling components have defects in hyphal development.

P14906	SEC63_YEAST	Protein translocation protein SEC63	11226176	Sec63p and Kar2p are required for the translocation of SRP-dependent precursors into the yeast endoplasmic reticulum in vivo.

P36163	OMA1_YEAST	Mitochondrial metalloendopeptidase OMA1	14562095	Global analysis of protein localization in budding yeast.

P69822	ULAB_ECOLI	Ascorbate-specific phosphotransferase enzyme IIB component	12644495	The ascorbate transporter of Escherichia coli.

P51149	RAB7A_HUMAN	Ras-related protein Rab-7a	8954989	Molecular cloning and expression analysis of the human Rab7 GTP-ase complementary deoxyribonucleic acid.

P06601	PRD_DROME	Segmentation protein paired	2877746	Structure of the segmentation gene paired and the Drosophila PRD gene set as part of a gene network.

P70587	LRRC7_RAT	Leucine-rich repeat-containing protein 7	8824323	Characterization of densin-180, a new brain-specific synaptic protein of the O-sialoglycoprotein family.

P0ABQ0	COABC_ECOLI	Coenzyme A biosynthesis bifunctional protein CoaBC	11278255	Phosphopantothenoylcysteine synthetase from Escherichia coli. Identification and characterization of the last unidentified coenzyme A biosynthetic enzyme in bacteria.

P40522	VHR1_YEAST	Transcription factor VHR1	14562095	Global analysis of protein localization in budding yeast.

O94532	FOR3_SCHPO	Formin-3	12415007	The small GTPase Rho3 and the diaphanous/formin For3 function in polarized cell growth in fission yeast.

Q9BZG8	DPH1_HUMAN	Diphthamide biosynthesis protein 1	8603384	A cDNA from the ovarian cancer critical region of deletion on chromosome 17p13.3.

Q08708	CLM6_HUMAN	CMRF35-like molecule 6	1349532	Molecular cloning of a novel member of the immunoglobulin gene superfamily homologous to the polymeric immunoglobulin receptor.

P25063	CD24_HUMAN	Signal transducer CD24	8753773	Association of CD24 with the kinase c-fgr in a small cell lung cancer cell line and with the kinase lyn in an erythroleukemia cell line.

Q09725	MIS4_SCHPO	Sister chromatid cohesion protein mis4	11882285	Requirement of chromatid cohesion proteins rad21/scc1 and mis4/scc2 for normal spindle-kinetochore interaction in fission yeast.

Q9SLH3	RGA_ARATH	DELLA protein RGA	15161962	The Arabidopsis mutant sleepy1gar2-1 protein promotes plant growth by increasing the affinity of the SCFSLY1 E3 ubiquitin ligase for DELLA protein substrates.

Q91WZ8	DTBP1_MOUSE	Dysbindin	1936982	Sandy: a new mouse model for platelet storage pool deficiency.

Q00013	EM55_HUMAN	55 kDa erythrocyte membrane protein	1713685	Molecular identification of a major palmitoylated erythrocyte membrane protein containing the src homology 3 motif.

P26393	RMLA_SALTY	Glucose-1-phosphate thymidylyltransferase	11373625	Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization.

P53176	MST27_YEAST	Multicopy suppressor of SEC21 protein 27	12101299	Functional analysis of the Saccharomyces cerevisiae DUP240 multigene family reveals membrane-associated proteins that are not essential for cell viability.

O60016	CLR4_SCHPO	Histone-lysine N-methyltransferase, H3 lysine-9 specific	9620780	The chromo and SET domains of the Clr4 protein are essential for silencing in fission yeast.

O95259	KCNH1_HUMAN	Potassium voltage-gated channel subfamily H member 1	9738473	Cloning of a human ether-a-go-go potassium channel expressed in myoblasts at the onset of fusion.

Q15796	SMAD2_HUMAN	Mothers against decapentaplegic homolog 2	18568018	TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal.

O42917	ESO1_SCHPO	N-acetyltransferase eso1	11598020	Establishment and maintenance of sister chromatid cohesion in fission yeast by a unique mechanism.

Q03562	BRE3_CAEEL	Beta-1,4-mannosyltransferase bre-3	12944392	Resistance to a bacterial toxin is mediated by removal of a conserved glycosylation pathway required for toxin-host interactions.

P15918	RAG1_HUMAN	V(D)J recombination-activating protein 1	9630231	Partial V(D)J recombination activity leads to Omenn syndrome.

Q8N9L9	ACOT4_HUMAN	Acyl-coenzyme A thioesterase 4	16940157	Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs.

Q3U962	CO5A2_MOUSE	Collagen alpha-2(V) chain	15199158	Development of a functional skin matrix requires deposition of collagen V heterotrimers.

P09208	INSR_DROME	Insulin-like receptor	11292875	A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function.

Q8TAD8	SNIP1_HUMAN	Smad nuclear-interacting protein 1	18632581	The FHA domain proteins DAWDLE in Arabidopsis and SNIP1 in humans act in small RNA biogenesis.

Q03920	MTQ2_YEAST	eRF1 methyltransferase catalytic subunit MTQ2	15509572	The glutamine residue of the conserved GGQ motif in Saccharomyces cerevisiae release factor eRF1 is methylated by the product of the YDR140w gene.

Q12979	ABR_HUMAN	Active breakpoint cluster region-related protein	8262969	The human active breakpoint cluster region-related gene encodes a brain protein with homology to guanine nucleotide exchange proteins and GTPase-activating proteins.

Q7ZX03	FOXK2_XENLA	Forkhead box protein K2	15656969	Of fox and frogs: fox (fork head/winged helix) transcription factors in Xenopus development.

Q9TZD0	LST2_CAEEL	Lateral signaling target protein 2	14752159	Crosstalk between the EGFR and LIN-12/Notch pathways in C. elegans vulval development.

Q9H422	HIPK3_HUMAN	Homeodomain-interacting protein kinase 3	14766760	JNK regulates HIPK3 expression and promotes resistance to Fas- mediated apoptosis in DU 145 prostate carcinoma cells.

P07919	QCR6_HUMAN	Cytochrome b-c1 complex subunit 6, mitochondrial	2826252	An extremely acidic amino-terminal presequence of the precursor for the human mitochondrial hinge protein.

P21263	NEST_RAT	Nestin	1689217	CNS stem cells express a new class of intermediate filament protein.

Q06672	TSR2_YEAST	Pre-rRNA-processing protein TSR2	14562095	Global analysis of protein localization in budding yeast.

P10966	CD8B_HUMAN	T-cell surface glycoprotein CD8 beta chain	3145195	A second subunit of CD8 is expressed in human T cells.

Q9VN41	SLX1_DROME	Structure-specific endonuclease subunit SLX1 homolog	19596236	Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases.

Q5W1J5	FOXP1_XENLA	Forkhead box protein P1	16609867	The FoxP subclass in Xenopus laevis development.

O75973	C1QRF_HUMAN	C1q-related factor	9878755	Cloning and characterization of CRF, a novel C1q-related factor, expressed in areas of the brain involved in motor function.

P03485	M1_I34A1	Matrix protein 1	11222100	In vitro dissection of the membrane and RNP binding activities of influenza virus M1 protein.

Q9M086	DCAF1_ARATH	DDB1- and CUL4-associated factor homolog 1	18552200	Arabidopsis DDB1-CUL4 ASSOCIATED FACTOR1 forms a nuclear E3 ubiquitin ligase with DDB1 and CUL4 that is involved in multiple plant developmental processes.

P35527	K1C9_HUMAN	Keratin, type I cytoskeletal 9	7507869	Molecular characterization of the body site-specific human epidermal cytokeratin 9: cDNA cloning, amino acid sequence, and tissue specificity of gene expression.

P40376	KAPB_SCHPO	cAMP-dependent protein kinase catalytic subunit	8144551	Cloning of the pka1 gene encoding the catalytic subunit of the cAMP- dependent protein kinase in Schizosaccharomyces pombe.

Q04472	MGR3_YEAST	Mitochondrial inner membrane i-AAA protease supercomplex subunit MGR3	14562095	Global analysis of protein localization in budding yeast.

Q9C005	DPY30_HUMAN	Protein dpy-30 homolog	19556245	On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex.

Q55GF9	ICPA_DICDI	Inner centromere protein A	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

P48742	LHX1_HUMAN	LIM/homeobox protein Lhx1	9212161	Cloning, expression, and chromosomal localization to 11p12-13 of a human LIM/homeobox gene, hLim-1.

O60999	CUL1_DICDI	Cullin-1	11390363	Regulated protein degradation controls PKA function and cell-type differentiation in Dictyostelium.

P31645	SC6A4_HUMAN	Sodium-dependent serotonin transporter	17506858	Plasma serotonin levels and the platelet serotonin transporter.

Q04692	SMRCD_MOUSE	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1	8219362	The Etl-1 gene encodes a nuclear protein differentially expressed during early mouse development.

Q9XV66	UNC80_CAEEL	Protein unc-80	18336069	A putative cation channel, NCA-1, and a novel protein, UNC-80, transmit neuronal activity in C. elegans.

Q9VVT2	INDY1_DROME	Protein I'm not dead yet	11118146	Extended life-span conferred by cotransporter gene mutations in Drosophila.

Q6GN29	ATLA2_XENLA	Atlastin-2	19665976	A class of dynamin-like GTPases involved in the generation of the tubular ER network.

P24869	CG22_YEAST	G2/mitotic-specific cyclin-2	7622566	Members of the NAP/SET family of proteins interact specifically with B-type cyclins.

Q24298	CADE_DROME	DE-cadherin	7958432	A Drosophila homolog of cadherin associated with armadillo and essential for embryonic cell-cell adhesion.

P84807	CR25A_NAJHH	Cysteine-rich venom protein 25-A	15670767	Cobra venom contains a pool of cysteine-rich secretory proteins.

O54803	P2RX6_MOUSE	P2X purinoceptor 6	9852680	Cloning and characterization of the murine P2XM receptor gene.

P42641	OBG_ECOLI	GTPase ObgE/CgtA	17578452	Chromosome segregation control by Escherichia coli ObgE GTPase.

P04147	PABP_YEAST	Polyadenylate-binding protein, cytoplasmic and nuclear	16809762	Tpa1p is part of an mRNP complex that influences translation termination, mRNA deadenylation, and mRNA turnover in Saccharomyces cerevisiae.

Q96PH1	NOX5_HUMAN	NADPH oxidase 5	11483596	A Ca(2+)-activated NADPH oxidase in testis, spleen, and lymph nodes.

O76071	CIAO1_HUMAN	Probable cytosolic iron-sulfur protein assembly protein CIAO1	17937914	Structure of the yeast WD40 domain protein Cia1, a component acting late in iron-sulfur protein biogenesis.

O15259	NPHP1_HUMAN	Nephrocystin-1	9361039	A novel gene that encodes a protein with a putative src homology 3 domain is a candidate gene for familial juvenile nephronophthisis.

Q03720	SLO_DROME	Calcium-activated potassium channel slowpoke	9502797	dSLo interacting protein 1, a novel protein that interacts with large-conductance calcium-activated potassium channels.

Q8N6T7	SIRT6_HUMAN	NAD-dependent deacetylase sirtuin-6	19135889	SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span.

P52655	TF2AA_HUMAN	Transcription initiation factor IIA subunit 1	8224850	Isolation of a cDNA encoding the largest subunit of TFIIA reveals functions important for activated transcription.

Q8K0H5	TAF10_MOUSE	Transcription initiation factor TFIID subunit 10	10469660	Mammalian TAFII30 is required for cell cycle progression and specific differentiation programmes.

Q63415	PCSK6_RAT	Proprotein convertase subtilisin/kexin type 6	8070361	PACE4: a subtilisin-like endoprotease prevalent in the anterior pituitary and regulated by thyroid status.

P17094	RL31_ARATH	60S ribosomal protein L3-1	2227432	Two evolutionarily divergent genes encode a cytoplasmic ribosomal protein of Arabidopsis thaliana.

P84884	AFP1_PASED	Antifungal protein 1	16766236	An antifungal peptide from passion fruit (Passiflora edulis) seeds with similarities to 2S albumin proteins.

O76460	RAD54_DROME	DNA repair and recombination protein RAD54-like	9732269	okra and spindle-B encode components of the RAD52 DNA repair pathway and affect meiosis and patterning in Drosophila oogenesis.

P38251	RFC5_YEAST	Replication factor C subunit 5	12912927	Elg1 forms an alternative RFC complex important for DNA replication and genome integrity.

Q07921	TEN1_YEAST	Telomere length regulation protein TEN1	11230140	Ten1 functions in telomere end protection and length regulation in association with Stn1 and Cdc13.

Q9M4A2	SPO11_ARATH	Meiotic recombination protein SPO11-1	17965269	The catalytically active tyrosine residues of both SPO11-1 and SPO11- 2 are required for meiotic double-strand break induction in Arabidopsis.

P27487	DPP4_HUMAN	Dipeptidyl peptidase 4	10900005	Internalization of CD26 by mannose 6-phosphate/insulin-like growth factor II receptr contributes to T cell activation.

Q8WWT9	S13A3_HUMAN	Solute carrier family 13 member 3	10794676	Structure, function, and genomic organization of human Na(+)- dependent high-affinity dicarboxylate transporter.

P37302	APE3_YEAST	Aminopeptidase Y	8175800	Molecular cloning of the aminopeptidase Y gene of Saccharomyces cerevisiae. Sequence analysis and gene disruption of a new aminopeptidase.

Q94AI7	TPL_ARATH	Protein TOPLESS	16763149	TOPLESS regulates apical embryonic fate in Arabidopsis.

Q12487	RM23_YEAST	54S ribosomal protein L23, mitochondrial	12392552	Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components.

Q9M2P7	PAP9_ARATH	Probable plastid-lipid-associated protein 9, chloroplastic	16414959	Tocopherol cyclase (VTE1) localization and vitamin E accumulation in chloroplast plastoglobule lipoprotein particles.

Q02354	UTP6_YEAST	U3 small nucleolar RNA-associated protein 6	17515605	The 90S preribosome is a multimodular structure that is assembled through a hierarchical mechanism.

Q99715	COCA1_HUMAN	Collagen alpha-1(XII) chain	1427837	The mouse alpha 1(XII) and human alpha 1(XII)-like collagen genes are localized on mouse chromosome 9 and human chromosome 6.

Q9QUH0	GLRX1_MOUSE	Glutaredoxin-1	10647820	Cloning and sequencing of mouse glutaredoxin (grx) cDNA.

P01123	YPT1_YEAST	GTP-binding protein YPT1	11785952	Saccharomyces cerevisiae Pra1p/Yip3p interacts with Yip1p and Rab proteins.

Q99MB1	TLR3_MOUSE	Toll-like receptor 3	17452530	The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling.

Q8R182	TMG2_MOUSE	Transmembrane gamma-carboxyglutamic acid protein 2	11042109	Identification of multiple proteins expressed in murine embryos as binding partners for the WW domains of the ubiquitin-protein ligase Nedd4.

P51878	CASP5_HUMAN	Caspase-5	7797592	Molecular cloning and pro-apoptotic activity of ICErelII and ICErelIII, members of the ICE/CED-3 family of cysteine proteases.

O95999	BCL10_HUMAN	B-cell lymphoma/leukemia 10	11466612	Interchangeable binding of Bcl10 to TRAF2 and cIAPs regulates apoptosis signaling.

P47045	TIM54_YEAST	Mitochondrial import inner membrane translocase subunit TIM54	10648604	Tim18p, a new subunit of the TIM22 complex that mediates insertion of imported proteins into the yeast mitochondrial inner membrane.

P51810	GP143_HUMAN	G-protein coupled receptor 143	19717472	The ocular albinism type 1 (OA1) G-protein-coupled receptor functions with MART-1 at early stages of melanogenesis to control melanosome identity and composition.

P38848	PEX28_YEAST	Peroxisomal membrane protein PEX28	12707309	YHR150w and YDR479c encode peroxisomal integral membrane proteins involved in the regulation of peroxisome number, size, and distribution in Saccharomyces cerevisiae.

P40480	HOS4_YEAST	Protein HOS4	11711434	The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program.

P48553	TPC10_HUMAN	Trafficking protein particle complex subunit 10	9196060	Genomic organization and complete nucleotide sequence of the TMEM1 gene on human chromosome 21q22.3.

O74375	TVP18_SCHPO	Golgi apparatus membrane protein tvp18	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q7G8V2	ARR15_ARATH	Two-component response regulator ARR15	12354925	Characterization of the ARR15 and ARR16 response regulators with special reference to the cytokinin signaling pathway mediated by the AHK4 histidine kinase in roots of Arabidopsis thaliana.

Q21955	MED15_CAEEL	Mediator of RNA polymerase II transcription subunit 15	16651656	A Mediator subunit, MDT-15, integrates regulation of fatty acid metabolism by NHR-49-dependent and -independent pathways in C. elegans.

O00762	UBE2C_HUMAN	Ubiquitin-conjugating enzyme E2 C	9122200	Dominant-negative cyclin-selective ubiquitin carrier protein E2- C/UbcH10 blocks cells in metaphase.

O43683	BUB1_HUMAN	Mitotic checkpoint serine/threonine-protein kinase BUB1	9521327	Mutations of mitotic checkpoint genes in human cancers.

O75437	ZN254_HUMAN	Zinc finger protein 254	10585455	Molecular cloning of six novel Kruppel-like zinc finger genes from hematopoietic cells and identification of a novel transregulatory domain KRNB.

P53266	SHY1_YEAST	Cytochrome oxidase assembly protein SHY1	17882259	Shy1 couples Cox1 translational regulation to cytochrome c oxidase assembly.

O35164	MCPT9_MOUSE	Mast cell protease 9	9360993	Mouse mast cell protease 9, a novel member of the chromosome 14 family of serine proteases that is selectively expressed in uterine mast cells.

P47712	PA24A_HUMAN	Cytosolic phospholipase A2	8381049	cPLA2 is phosphorylated and activated by MAP kinase.

P54144	AMT11_ARATH	Ammonium transporter 1 member 1	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P85078	3CP2_STRSQ	Tricyclic peptide MS-271	8689231	MS-271, a novel inhibitor of calmodulin-activated myosin light chain kinase from Streptomyces sp. -- I. Isolation, structural determination and biological properties of MS-271.

P21182	DCAM_YEAST	S-adenosylmethionine decarboxylase proenzyme	2266128	Spermidine biosynthesis in Saccharomyces cerevisiae. Biosynthesis and processing of a proenzyme form of S-adenosylmethionine decarboxylase.

P07101	TY3H_HUMAN	Tyrosine 3-monooxygenase	2896667	Expression of human tyrosine hydroxylase cDNA in invertebrate cells using a baculovirus vector.

Q9WTZ2	MBTP1_MOUSE	Membrane-bound transcription factor site-1 protease	9990022	Mammalian subtilisin/kexin isozyme SKI-1: a widely expressed proprotein convertase with a unique cleavage specificity and cellular localization.

Q9UQ84	EXO1_HUMAN	Exonuclease 1	15225546	A defined human system that supports bidirectional mismatch-provoked excision.

Q09161	NCBP1_HUMAN	Nuclear cap-binding protein subunit 1	9111328	Interaction between the human nuclear cap-binding protein complex and hnRNP F.

P41237	CTXN1_RAT	Cortexin-1	8336151	Identification of cortexin: a novel, neuron-specific, 82-residue membrane protein enriched in rodent cerebral cortex.

P16444	DPEP1_HUMAN	Dipeptidase 1	2303490	Primary structure of human microsomal dipeptidase deduced from molecular cloning.

Q12129	NMD4_YEAST	Nonsense-mediated decay protein 4	7883168	Identification of a novel component of the nonsense-mediated mRNA decay pathway by use of an interacting protein screen.

Q9Z335	SBK1_RAT	Serine/threonine-protein kinase SBK1	11322885	Cloning and characterization of a novel serine/threonine protein kinase gene expressed predominantly in developing brain.

Q8WTC1	RT15_DROME	28S ribosomal protein S15, mitochondrial	14651932	Bonsai, a ribosomal protein S15 homolog, involved in gut mitochondrial activity and systemic growth.

Q04373	PUF6_YEAST	Pumilio homology domain family member 6	15198983	A new yeast PUF family protein, Puf6p, represses ASH1 mRNA translation and is required for its localization.

P24941	CDK2_HUMAN	Cell division protein kinase 2	8601310	Crystal structure and mutational analysis of the human CDK2 kinase complex with cell cycle-regulatory protein CksHs1.

Q43725	CYSKM_ARATH	Cysteine synthase, mitochondrial	10940562	Genomic and functional characterization of the oas gene family encoding O-acetylserine (thiol) lyases, enzymes catalyzing the final step in cysteine biosynthesis in Arabidopsis thaliana.

Q7KZI7	MARK2_HUMAN	Serine/threonine-protein kinase MARK2	9730619	Human serine/threonine protein kinase EMK1: genome structure and cDNA cloning of isoforms produced by alternative splicing.

Q06418	TYRO3_HUMAN	Tyrosine-protein kinase receptor TYRO3	7511603	RSE, a novel receptor-type tyrosine kinase with homology to Axl/Ufo, is expressed at high levels in the brain.

Q99N80	SYTL1_MOUSE	Synaptotagmin-like protein 1	11243866	Synaptotagmin-like protein 1-3: a novel family of C-terminal-type tandem C2 proteins.

P52480	KPYM_MOUSE	Pyruvate kinase isozymes M1/M2	18191611	Pyruvate kinase isozyme type M2 (PKM2) interacts and cooperates with Oct-4 in regulating transcription.

Q15784	NDF2_HUMAN	Neurogenic differentiation factor 2	8816493	NeuroD2 and neuroD3: distinct expression patterns and transcriptional activation potentials within the neuroD gene family.

P37238	PPARG_MOUSE	Peroxisome proliferator-activated receptor gamma	8041794	Differential expression and activation of a family of murine peroxisome proliferator-activated receptors.

Q10953	WRM1_CAEEL	Armadillo repeat-containing protein wrm-1	16890160	Crosstalk between a nuclear receptor and beta-catenin signaling decides cell fates in the C. elegans somatic gonad.

Q9ZQ99	COGT1_ARATH	Cytokinin-O-glucosyltransferase 1	15342621	N-glucosylation of cytokinins by glycosyltransferases of Arabidopsis thaliana.

P31430	DPEP1_RAT	Dipeptidase 1	1420313	Primary structure of rat renal dipeptidase and expression of its mRNA in rat tissues and COS-1 cells.

O23463	CMTA5_ARATH	Calmodulin-binding transcription activator 5	12218065	A calmodulin-binding/CGCG box DNA-binding protein family involved in multiple signaling pathways in plants.

O61735	CLOCK_DROME	Circadian locomoter output cycles protein kaput	9630223	A mutant Drosophila homolog of mammalian Clock disrupts circadian rhythms and transcription of period and timeless.

Q9WUB0	UB7I3_MOUSE	RanBP-type and C3HC4-type zinc finger-containing protein 1	19136968	Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation.

P62701	RS4X_HUMAN	40S ribosomal protein S4, X isoform	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

Q02575	HEN1_HUMAN	Helix-loop-helix protein 1	1328219	A comparative structural characterization of the human NSCL-1 and NSCL-2 genes. Two basic helix-loop-helix genes expressed in the developing nervous system.

P07308	ACOD1_RAT	Acyl-CoA desaturase 1	12419843	Stearoyl-CoA desaturase 1 (Scd1) gene overexpression is associated with genetic predisposition to hepatocarcinogenesis in mice and rats.

Q5U4X3	MEI3A_XENLA	Homeobox protein meis3-A	11566848	XMeis3 protein activity is required for proper hindbrain patterning in Xenopus laevis embryos.

Q9TW65	DMD_CAEEL	Dystrophin-1	10369883	Dystrobrevin- and dystrophin-like mutants display similar phenotypes in the nematode Caenorhabditis elegans.

Q9ASX5	Y5520_ARATH	Uncharacterized aarF domain-containing protein kinase At5g05200, chloroplastic	16414959	Tocopherol cyclase (VTE1) localization and vitamin E accumulation in chloroplast plastoglobule lipoprotein particles.

Q90ZH7	SX18B_XENLA	Transcription factor Sox-18B	16193513	SOX7 and SOX18 are essential for cardiogenesis in Xenopus.

Q08369	GATA4_MOUSE	Transcription factor GATA-4	15542826	Jumonji represses atrial natriuretic factor gene expression by inhibiting transcriptional activities of cardiac transcription factors.

P84249	H33_DROME	Histone H3.3	1748304	A Drosophila melanogaster H3.3 cDNA encodes a histone variant identical with the vertebrate H3.3.

Q8JZM4	DNER_MOUSE	Delta and Notch-like epidermal growth factor-related receptor	15965470	DNER acts as a neuron-specific Notch ligand during Bergmann glial development.

Q08280	BSC6_YEAST	Bypass of stop codon protein 6	14562095	Global analysis of protein localization in budding yeast.

P23639	PSA2_YEAST	Proteasome component Y7	9087403	Structure of 20S proteasome from yeast at 2.4-A resolution.

O14275	YET6_SCHPO	Pentatricopeptide repeat-containing protein C8C9.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9FLB1	PYL5_ARATH	Abscisic acid receptor PYL5	19874541	PYR/PYL/RCAR family members are major in-vivo ABI1 protein phosphatase 2C-interacting proteins in Arabidopsis.

Q8IW35	CEP97_HUMAN	Centrosomal protein of 97 kDa	17719545	Cep97 and CP110 suppress a cilia assembly program.

P36144	RL1D1_YEAST	Ribosome biogenesis protein UTP30	14562095	Global analysis of protein localization in budding yeast.

Q19289	IFB1_CAEEL	Intermediate filament protein ifb-1	11427699	Essential roles for four cytoplasmic intermediate filament proteins in Caenorhabditis elegans development.

P39721	AIM2_YEAST	Protein AIM2	14562095	Global analysis of protein localization in budding yeast.

P13601	AL1A7_RAT	Aldehyde dehydrogenase, cytosolic 1	2753900	Phenobarbital-inducible aldehyde dehydrogenase in the rat. cDNA sequence and regulation of the mRNA by phenobarbital in responsive rats.

P08697	A2AP_HUMAN	Alpha-2-antiplasmin	2830248	Structure of human alpha 2-plasmin inhibitor deduced from the cDNA sequence.

Q9ES40	PRAF3_RAT	PRA1 family protein 3	11242046	Modulation of the neuronal glutamate transporter EAAC1 by the interacting protein GTRAP3-18.

O70152	DPM1_MOUSE	Dolichol-phosphate mannosyltransferase	9535917	A homologue of Saccharomyces cerevisiae Dpm1p is not sufficient for synthesis of dolichol-phosphate-mannose in mammalian cells.

Q8CG64	FKRP_MOUSE	Fukutin-related protein	17452335	Fukutin-related protein associates with the sarcolemmal dystrophin- glycoprotein complex.

P02283	H2B_DROME	Histone H2B	117830	Sequence of histone 2B of Drosophila melanogaster.

O65469	CRK9_ARATH	Putative cysteine-rich receptor-like protein kinase 9	16307367	Identification of NPR1-dependent and independent genes early induced by salicylic acid treatment in Arabidopsis.

P06700	SIR2_YEAST	NAD-dependent histone deacetylase SIR2	10693811	Transcriptional silencing and longevity protein Sir2 is an NAD- dependent histone deacetylase.

Q6NS38	ALKB2_HUMAN	Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2	18432238	Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA.

P46531	NOTC1_HUMAN	Neurogenic locus notch homolog protein 1	16025100	Mutations in NOTCH1 cause aortic valve disease.

P22561	WT1_MOUSE	Wilms tumor protein homolog	9784496	WT1 interacts with the splicing factor U2AF65 in an isoform-dependent manner and can be incorporated into spliceosomes.

P0A9K9	SLYD_ECOLI	FKBP-type peptidyl-prolyl cis-trans isomerase slyD	19947632	The Ni(II)-binding properties of the metallochaperone SlyD.

Q6P4F1	FUT10_HUMAN	Alpha-(1,3)-fucosyltransferase 10	11698403	Composition of Drosophila melanogaster proteome involved in fucosylated glycan metabolism.

P61024	CKS1_HUMAN	Cyclin-dependent kinases regulatory subunit 1	8601310	Crystal structure and mutational analysis of the human CDK2 kinase complex with cell cycle-regulatory protein CksHs1.

Q03419	IZH1_YEAST	ADIPOR-like receptor IZH1	15060275	Metalloregulation of yeast membrane steroid receptor homologs.

P49768	PSN1_HUMAN	Presenilin-1	10551805	Identification of a novel PSD-95/Dlg/ZO-1 (PDZ)-like protein interacting with the C terminus of presenilin-1.

Q07878	VPS13_YEAST	Vacuolar protein sorting-associated protein 13	9314526	SOI1 encodes a novel, conserved protein that promotes TGN-endosomal cycling of Kex2p and other membrane proteins by modulating the function of two TGN localization signals.

Q8I5P7	SYSC_PLAF7	Seryl-tRNA synthetase, cytoplasmic	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

O14657	TOR1B_HUMAN	Torsin-1B	9288096	The early-onset torsion dystonia gene (DYT1) encodes an ATP-binding protein.

P39748	FEN1_HUMAN	Flap endonuclease 1	7961795	Structural and functional homology between mammalian DNase IV and the 5'-nuclease domain of Escherichia coli DNA polymerase I.

P84679	SC33_TITCA	Toxin Tc33	15025998	Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

P41273	TNFL9_HUMAN	Tumor necrosis factor ligand superfamily member 9	8088337	Molecular and biological characterization of human 4-1BB and its ligand.

Q61955	KLK8_MOUSE	Kallikrein-8	16308352	Neuropsin is essential for early processes of memory acquisition and Schaffer collateral long-term potentiation in adult mouse hippocampus in vivo.

P38170	CND2_YEAST	Condensin complex subunit 2	10749931	Chromosome condensation factor Brn1p is required for chromatid separation in mitosis.

O70585	DTNB_MOUSE	Dystrobrevin beta	11316798	Dysbindin, a novel coiled-coil-containing protein that interacts with the dystrobrevins in muscle and brain.

Q9Y7Y7	GAS4_SCHPO	1,3-beta-glucanosyltransferase gas4	18410286	The beta-1,3-glucanosyltransferase gas4p is essential for ascospore wall maturation and spore viability in Schizosaccharomyces pombe.

P35568	IRS1_HUMAN	Insulin receptor substrate 1	7541045	Non-SH2 domains within insulin receptor substrate-1 and SHC mediate their phosphotyrosine-dependent interaction with the NPEY motif of the insulin-like growth factor I receptor.

P81919	OR46A_DROME	Odorant receptor 46a, isoform A	10069338	A novel family of divergent seven-transmembrane proteins: candidate odorant receptors in Drosophila.

P53992	SC24C_HUMAN	Protein transport protein Sec24C	10329445	A family of mammalian proteins homologous to yeast Sec24p.

Q54ET0	GRLE_DICDI	Metabotropic glutamate receptor-like protein E	16527814	A metabotropic glutamate receptor family gene in Dictyostelium discoideum.

Q9NL89	BGBP_BOMMO	Beta-1,3-glucan-binding protein	10671539	A pattern-recognition protein for beta-1,3-glucan. The binding domain and the cDNA cloning of beta-1,3-glucan recognition protein from the silkworm, Bombyx mori.

Q9BTX1	NDC1_HUMAN	Nucleoporin NDC1	16600873	The conserved transmembrane nucleoporin NDC1 is required for nuclear pore complex assembly in vertebrate cells.

P53193	JAC1_YEAST	J-type co-chaperone JAC1, mitochondrial	12756240	Ssq1, a mitochondrial Hsp70 involved in iron-sulfur (Fe/S) center biogenesis. Similarities to and differences from its bacterial counterpart.

Q04658	SMA2_YEAST	Spore membrane assembly protein 2	11470404	A screen for genes required for meiosis and spore formation based on whole-genome expression.

P40963	SAS2_YEAST	Histone acetyltransferase SAS2	12626510	Sas4 and Sas5 are required for the histone acetyltransferase activity of Sas2 in the SAS complex.

Q93646	SNT1_CAEEL	Syntrophin-1	12234669	Genetic evidence for a dystrophin-glycoprotein complex (DGC) in Caenorhabditis elegans.

Q9Z2Z7	PGPS1_CRIGR	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial	9880566	Isolation of a chinese hamster ovary (CHO) cDNA encoding phosphatidylglycerophosphate (PGP) synthase, expression of which corrects the mitochondrial abnormalities of a PGP synthase-defective mutant of CHO-K1 cells.

Q01726	MSHR_HUMAN	Melanocyte-stimulating hormone receptor	9571181	Human pigmentation phenotype: a point mutation generates nonfunctional MSH receptor.

Q8TEY7	UBP33_HUMAN	Ubiquitin carboxyl-terminal hydrolase 33	19363159	Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2.

P07773	CATA_ACIAD	Catechol 1,2-dioxygenase	10801478	The 1.8 A crystal structure of catechol 1,2-dioxygenase reveals a novel hydrophobic helical zipper as a subunit linker.

P38344	REI1_YEAST	Pre-60S factor REI1	16648468	Nuclear recycling of the pre-60S ribosomal subunit-associated factor Arx1 depends on Rei1 in Saccharomyces cerevisiae.

O97237	YGCC1_PLAF7	GRIP and coiled-coil domain-containing protein PFC0235w	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

Q03063	DIG1_YEAST	Down-regulator of invasive growth 1	8918885	Two novel targets of the MAP kinase Kss1 are negative regulators of invasive growth in the yeast Saccharomyces cerevisiae.

O00469	PLOD2_HUMAN	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2	9054364	Cloning and characterization of a novel human lysyl hydroxylase isoform highly expressed in pancreas and muscle.

P25579	LRE1_YEAST	Laminarase-resistance protein LRE1	11532139	Hyperosmotic stress response and regulation of cell wall integrity in Saccharomyces cerevisiae share common functional aspects.

Q9NX02	NALP2_HUMAN	NACHT, LRR and PYD domains-containing protein 2	15030775	NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder.

Q16875	F263_HUMAN	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	8830046	Cloning of cDNA encoding for a novel isozyme of fructose 6-phosphate, 2-kinase/fructose 2,6-bisphosphatase from human placenta.

P03536	NSP3_ROTS1	Non-structural protein 3	12086624	Recognition of eIF4G by rotavirus NSP3 reveals a basis for mRNA circularization.

P13746	1A11_HUMAN	HLA class I histocompatibility antigen, A-11 alpha chain	2437024	DNA sequence of HLA-A11: remarkable homology with HLA-A3 allows identification of residues involved in epitopes recognized by antibodies and T cells.

P58952	GR22C_DROME	Putative gustatory receptor 22c	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

Q17353	PAR3_CAEEL	Partitioning defective protein 3	8521491	Asymmetrically distributed PAR-3 protein contributes to cell polarity and spindle alignment in early C. elegans embryos.

Q91904	FXI1A_XENLA	Forkhead box protein I1-A	7739038	DNA recognition site analysis of Xenopus winged helix proteins.

P77211	CUSC_ECOLI	Cation efflux system protein cusC	11283292	The product of the ybdE gene of the Escherichia coli chromosome is involved in detoxification of silver ions.

Q9UK45	LSM7_HUMAN	U6 snRNA-associated Sm-like protein LSm7	10523320	A doughnut-shaped heteromer of human Sm-like proteins binds to the 3'-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro.

P27843	YIGG_ECOLI	Inner membrane protein yigG	11867724	Rapid topology mapping of Escherichia coli inner-membrane proteins by prediction and PhoA/GFP fusion analysis.

Q16651	PRSS8_HUMAN	Prostasin	7768952	Molecular cloning, tissue-specific expression, and cellular localization of human prostasin mRNA.

Q01656	RSP4_CHLRE	Flagellar radial spoke protein 4	1508197	Sequence analysis reveals homology between two proteins of the flagellar radial spoke.

P29467	MEI4_YEAST	Meiosis-specific protein MEI4	16783010	Saccharomyces cerevisiae Mer2, Mei4 and Rec114 form a complex required for meiotic double-strand break formation.

P61073	CXCR4_HUMAN	C-X-C chemokine receptor type 4	9468539	Genomic organization and functional characterization of the chemokine receptor CXCR4, a major entry co-receptor for human immunodeficiency virus type 1.

Q14032	BAAT_HUMAN	Bile acid-CoA:amino acid N-acyltransferase	8034703	Glycine and taurine conjugation of bile acids by a single enzyme. Molecular cloning and expression of human liver bile acid CoA:amino acid N-acyltransferase.

P47104	RAV1_YEAST	Regulator of V-ATPase in vacuolar membrane protein 1	15090613	Soi3p/Rav1p functions at the early endosome to regulate endocytic trafficking to the vacuole and localization of trans-Golgi network transmembrane proteins.

Q9Z118	ROD1_RAT	Regulator of differentiation 1	10207106	Isolation of a mammalian homologue of a fission yeast differentiation regulator.

Q9GCB9	RT02_ARATH	Ribosomal protein S2, mitochondrial	12369627	Plant mitochondrial rps2 genes code for proteins with a C-terminal extension that is processed.

P53260	GATF_YEAST	Glutamyl-tRNA(Gln) amidotransferase subunit F, mitochondrial	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Q9NQB0	TF7L2_HUMAN	Transcription factor 7-like 2	12408868	The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells.

Q8CEE0	CEP57_MOUSE	Centrosomal protein of 57 kDa	12954732	Tsp57: a novel gene induced during a specific stage of spermatogenesis.

Q9USQ1	CTF18_SCHPO	Chromosome transmission fidelity protein 18	15226378	Sister-chromatid cohesion mediated by the alternative RF- CCtf18/Dcc1/Ctf8, the helicase Chl1 and the polymerase-alpha- associated protein Ctf4 is essential for chromatid disjunction during meiosis II.

Q00874	DR100_ARATH	DNA-damage-repair/toleration protein DRT100	1518832	A plant cDNA that partially complements Escherichia coli recA mutations predicts a polypeptide not strongly homologous to RecA proteins.

Q95121	PEDF_BOVIN	Pigment epithelium-derived factor	7592790	Pigment epithelium-derived factor behaves like a noninhibitory serpin. Neurotrophic activity does not require the serpin reactive loop.

P11308	ERG_HUMAN	Transcriptional regulator ERG	3476934	The erg gene: a human gene related to the ets oncogene.

P84791	HBAD_AYTFU	Hemoglobin subunit alpha-D	15567161	Molecular mechanism of high altitude respiration: primary structure of a minor hemoglobin component from Tufted duck (Aythya fuligula, Anseriformes).

P15848	ARSB_HUMAN	Arylsulfatase B	1718978	Mucopolysaccharidosis VI (Maroteaux-Lamy syndrome). An intermediate clinical phenotype caused by substitution of valine for glycine at position 137 of arylsulfatase B.

P22147	XRN1_YEAST	5'-3' exoribonuclease 1	2076815	kem mutations affect nuclear fusion in Saccharomyces cerevisiae.

Q940X7	RBX1A_ARATH	RING-box protein 1a	12381738	The AtRbx1 protein is part of plant SCF complexes, and its down- regulation causes severe growth and developmental defects.

Q9P7D3	YOFG_SCHPO	WHI2-like protein P4H10.16c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q04272	VPS20_YEAST	Vacuolar protein sorting-associated protein 20	12953057	Vps20p and Vta1p interact with Vps4p and function in multivesicular body sorting and endosomal transport in Saccharomyces cerevisiae.

Q04049	POLH_YEAST	DNA polymerase eta	12110599	Lesion bypass in yeast cells: Pol eta participates in a multi-DNA polymerase process.

Q9H2X3	CLC4M_HUMAN	C-type lectin domain family 4 member M	10072769	Selection of cDNAs encoding putative type II membrane proteins on the cell surface from a human full-length cDNA bank.

Q02648	TRM44_YEAST	tRNA (uracil-O(2)-)-methyltransferase	14562095	Global analysis of protein localization in budding yeast.

Q9ESQ4	NMUR2_RAT	Neuromedin-U receptor 2	10894543	Identification of receptors for neuromedin U and its role in feeding.

Q7L0Y3	MRRP1_HUMAN	Mitochondrial ribonuclease P protein 1	18984158	RNase P without RNA: identification and functional reconstitution of the human mitochondrial tRNA processing enzyme.

Q9GZT4	SRR_HUMAN	Serine racemase	11054547	Human serine racemase: molecular cloning, genomic organization and functional expression.

O00507	USP9Y_HUMAN	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y	8922996	The Drosophila developmental gene fat facets has a human homologue in Xp11.4 which escapes X-inactivation and has related sequences on Yq11.2.

P53923	CTU2_YEAST	Cytoplasmic tRNA 2-thiolation protein 2	18664566	Thio-modification of yeast cytosolic tRNA requires a ubiquitin- related system that resembles bacterial sulfur transfer systems.

P19878	NCF2_HUMAN	Neutrophil cytosol factor 2	11090627	Structure of the TPR domain of p67phox in complex with Rac.GTP.

Q02724	ULP1_YEAST	Ubiquitin-like-specific protease 1	10094048	A new protease required for cell-cycle progression in yeast.

Q8I2A6	CBPZ1_PLAF7	Putative zinc carboxypeptidase PFA0170c	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

Q940X7	RBX1A_ARATH	RING-box protein 1a	12215511	Role of the Arabidopsis RING-H2 protein RBX1 in RUB modification and SCF function.

O15305	PMM2_HUMAN	Phosphomannomutase 2	9140401	Mutations in PMM2, a phosphomannomutase gene on chromosome 16p13, in carbohydrate-deficient glycoprotein type I syndrome (Jaeken syndrome).

Q8BX90	FND3A_MOUSE	Fibronectin type-III domain-containing protein 3A	16904100	FNDC3A is required for adhesion between spermatids and Sertoli cells.

P35556	FBN2_HUMAN	Fibrillin-2	8120105	Structure and expression of fibrillin-2, a novel microfibrillar component preferentially located in elastic matrices.

Q08760	RAX1_YEAST	Bud site selection protein RAX1	14980713	Rax1, a protein required for the establishment of the bipolar budding pattern in yeast.

P50442	GATM_RAT	Glycine amidinotransferase, mitochondrial	8021264	Cloning and sequencing of rat kidney L-arginine:glycine amidinotransferase. Studies on the mechanism of regulation by growth hormone and creatine.

P53746	FRE4_YEAST	Ferric reductase transmembrane component 4	11120744	The role of the FRE family of plasma membrane reductases in the uptake of siderophore-iron in Saccharomyces cerevisiae.

Q10469	MGAT2_HUMAN	Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	7635144	The human UDP-N-acetylglucosamine: alpha-6-D-mannoside-beta-1,2-N- acetylglucosaminyltransferase II gene (MGAT2). Cloning of genomic DNA, localization to chromosome 14q21, expression in insect cells and purification of the recombinant protein.

Q9BRX9	WDR83_HUMAN	WD repeat domain-containing protein 83	11991638	Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.

Q8R1B5	CPLX3_MOUSE	Complexin-3	15911881	Structurally and functionally unique complexins at retinal ribbon synapses.

Q08438	VHS3_YEAST	Protein VHS3	15192104	Functional characterization of the Saccharomyces cerevisiae VHS3 gene. A regulatory subunit of the Ppz1 protein phosphatase with novel, phosphatase-unrelated functions.

P53930	AF9_YEAST	Protein AF-9 homolog	14562095	Global analysis of protein localization in budding yeast.

Q9H2R5	KLK15_HUMAN	Kallikrein-15	8018728	A novel serine proteinase-like sequence from human brain.

P08729	K2C7_HUMAN	Keratin, type II cytoskeletal 7	2415537	Sequence and expression of a human type II mesothelial keratin.

O00291	HIP1_HUMAN	Huntingtin-interacting protein 1	11577110	Clathrin- and AP-2-binding sites in HIP1 uncover a general assembly role for endocytic accessory proteins.

P13712	MSI1_YEAST	Chromatin assembly factor 1 subunit p50	9030687	Ultraviolet radiation sensitivity and reduction of telomeric silencing in Saccharomyces cerevisiae cells lacking chromatin assembly factor-I.

P0AA89	DOSC_ECOLI	Diguanylate cyclase DosC	17010156	Cyclic-di-GMP-mediated signalling within the sigma network of Escherichia coli.

P28799	GRN_HUMAN	Granulins	1542665	Isolation and sequence of the granulin precursor cDNA from human bone marrow reveals tandem cysteine-rich granulin domains.

A7LFZ6	DCL4_ORYSJ	Endoribonuclease Dicer homolog 4	17804793	The small interfering RNA production pathway is required for shoot meristem initiation in rice.

Q84J50	HS177_ORYSJ	17.7 kDa class I heat shock protein	19703271	Rice sHsp genes: genomic organization and expression profiling under stress and development.

Q06135	GAS2_YEAST	1,3-beta-glucanosyltransferase GAS2	17397106	The Gas family of proteins of Saccharomyces cerevisiae: characterization and evolutionary analysis.

P51654	GPC3_HUMAN	Glypican-3	8589713	Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome.

Q75GK0	IAA11_ORYSJ	Auxin-responsive protein IAA11	16200395	Structure and expression analysis of early auxin-responsive Aux/IAA gene family in rice (Oryza sativa).

Q9UW13	PALF_CANAL	pH-response regulator protein palF/RIM8	10601209	PRR1, a homolog of Aspergillus nidulans palF, controls pH-dependent gene expression and filamentation in Candida albicans.

P35427	RL13A_RAT	60S ribosomal protein L13a	8119894	A leucine zipper-like motif and a basic region-leucine zipper-like element in rat ribosomal protein L13a. Identification of the tum- transplantation antigen P198.

P77425	ALLC_ECOLI	Allantoate amidohydrolase	17362992	Structural analysis of a ternary complex of allantoate amidohydrolase from Escherichia coli reveals its mechanics.

P07207	NOTCH_DROME	Neurogenic locus Notch protein	15620649	Drosophila Nedd4 regulates endocytosis of notch and suppresses its ligand-independent activation.

O14843	FFAR3_HUMAN	Free fatty acid receptor 3	9344866	A cluster of four novel human G protein-coupled receptor genes occurring in close proximity to CD22 gene on chromosome 19q13.1.

Q06554	IRC20_YEAST	Uncharacterized ATP-dependent helicase IRC20	14562095	Global analysis of protein localization in budding yeast.

P80428	ARP4_YEAST	Actin-related protein 4	12353039	Acetylation of histone H4 by Esa1 is required for DNA double-strand break repair.

P51541	KARG_LIMPO	Arginine kinase	7819288	Isolation and sequence analysis of the gene for arginine kinase from the chelicerate arthropod, Limulus polyphemus: insights into catalytically important residues.

O60663	LMX1B_HUMAN	LIM homeobox transcription factor 1-beta	9590287	Mutations in LMX1B cause abnormal skeletal patterning and renal dysplasia in nail patella syndrome.

P38398	BRCA1_HUMAN	Breast cancer type 1 susceptibility protein	17525340	Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response.

P41595	5HT2B_HUMAN	5-hydroxytryptamine receptor 2B	8143856	Cloning and functional characterization of the human 5-HT2B serotonin receptor.

Q9USM9	COQ10_SCHPO	Coenzyme Q-binding protein coq10, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P16649	TUP1_YEAST	General transcriptional corepressor TUP1	14525981	Tup1-Ssn6 interacts with multiple class I histone deacetylases in vivo.

P42774	GBF1_ARATH	G-box-binding factor 1	1373374	Heterodimerization between light-regulated and ubiquitously expressed Arabidopsis GBF bZIP proteins.

Q12983	BNIP3_HUMAN	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3	10381623	A novel adenovirus E1B19K-binding protein B5 inhibits apoptosis induced by Nip3 by forming a heterodimer through the C-terminal hydrophobic region.

Q9QZM2	DPOG2_MOUSE	DNA polymerase subunit gamma-2, mitochondrial	11172710	Crystal structure and deletion analysis show that the accessory subunit of mammalian DNA polymerase gamma, Pol gamma B, functions as a homodimer.

Q9D415	DLGP1_MOUSE	Disks large-associated protein 1	15024750	Differential mRNA expression and protein localization of the SAP90/PSD-95-associated proteins (SAPAPs) in the nervous system of the mouse.

O00148	DDX39_HUMAN	ATP-dependent RNA helicase DDX39	15047853	Growth-regulated expression and G0-specific turnover of the mRNA that encodes URH49, a mammalian DExH/D box protein that is highly related to the mRNA export protein UAP56.

P48607	SPZ_DROME	Protein spaetzle	8808632	The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults.

P40063	RT105_YEAST	Regulator of Ty1 transposition protein 105	14562095	Global analysis of protein localization in budding yeast.

Q9UUB5	MIS13_SCHPO	Kinetochore protein mis13	17035632	Reconstruction of the kinetochore during meiosis in fission yeast Schizosaccharomyces pombe.

O75340	PDCD6_HUMAN	Programmed cell death protein 6	18256029	Identification of Alix-type and non-Alix-type ALG-2-binding sites in human phospholipid scramblase 3: differential binding to an alternatively spliced isoform and amino acid-substituted mutants.

O94703	RPA12_SCHPO	DNA-directed RNA polymerase I subunit RPA12	11254133	Isolation and characterization of the fission yeast gene Sprpa12+ reveals that the conserved C-terminal zinc-finger region is dispensable for the function of its product.

O59790	ARK1_SCHPO	Serine/threonine-protein kinase ark1	11950927	The Schizosaccharomyces pombe aurora-related kinase Ark1 interacts with the inner centromere protein Pic1 and mediates chromosome segregation and cytokinesis.

O95251	MYST2_HUMAN	Histone acetyltransferase MYST2	10930412	Androgen receptor interacts with a novel MYST protein, HBO1.

Q9PTD7	CING_XENLA	Cingulin	12023291	Evidence for a functional interaction between cingulin and ZO-1 in cultured cells.

O35956	S22A6_RAT	Solute carrier family 22 member 6	9228014	Expression cloning and characterization of a novel multispecific organic anion transporter.

P38783	FYV4_YEAST	Protein FYV4, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

Q03251	GRP8_ARATH	Glycine-rich RNA-binding protein 8	7513083	Genes encoding glycine-rich Arabidopsis thaliana proteins with RNA- binding motifs are influenced by cold treatment and an endogenous circadian rhythm.

Q99102	MUC4_HUMAN	Mucin-4	10024507	Complete sequence of the human mucin MUC4: a putative cell membrane- associated mucin.

Q07303	EPOR_RAT	Erythropoietin receptor	7684373	Functional erythropoietin receptor of the cells with neural characteristics. Comparison with receptor properties of erythroid cells.

P24528	MGMT_RAT	Methylated-DNA--protein-cysteine methyltransferase	1945835	Cloning and expresion of cDNA for rat O6-methylguanine-DNA methyltransferase.

P83869	IM14_DROME	Immune-induced peptide 14	9736738	Differential display of peptides induced during the immune response of Drosophila: a matrix-assisted laser desorption ionization time-of- flight mass spectrometry study.

P35555	FBN1_HUMAN	Fibrillin-1	15165854	Molecular structure and interaction of recombinant human type XVI collagen.

P52566	GDIR2_HUMAN	Rho GDP-dissociation inhibitor 2	8262133	Identification of two human Rho GDP dissociation inhibitor proteins whose overexpression leads to disruption of the actin cytoskeleton.

P02675	FIBB_HUMAN	Fibrinogen beta chain	6688356	Characterization of complementary deoxyribonucleic acid and genomic deoxyribonucleic acid for the beta chain of human fibrinogen.

Q78PB6	NDEL1_RAT	Nuclear distribution protein nudE-like 1	15728732	Inhibition of NUDEL (nuclear distribution element-like)- oligopeptidase activity by disrupted-in-schizophrenia 1.

P38274	HSL7_YEAST	Protein arginine N-methyltransferase HSL7	10490648	Hsl7 localizes to a septin ring and serves as an adapter in a regulatory pathway that relieves tyrosine phosphorylation of Cdc28 protein kinase in Saccharomyces cerevisiae.

O04931	AGLU_BETVU	Alpha-glucosidase	7766184	Chemical modification and amino acid sequence of active site in sugar beet alpha-glucosidase.

Q12690	RL13A_YEAST	60S ribosomal protein L13-A	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q9HCX4	TRPC7_HUMAN	Short transient receptor potential channel 7	15757897	MxA, a member of the dynamin superfamily, interacts with the ankyrin- like repeat domain of TRPC.

Q9UU83	PAL1_SCHPO	Protein pal1	15975911	The novel fission yeast protein Pal1p interacts with Hip1-related Sla2p/End4p and is involved in cellular morphogenesis.

Q08641	AB140_YEAST	Uncharacterized methyltransferase ABP140	9467951	Isolation and characterization of a novel actin filament-binding protein from Saccharomyces cerevisiae.

P40554	URM1_YEAST	Ubiquitin-related modifier 1	10713047	A protein conjugation system in yeast with homology to biosynthetic enzyme reaction of prokaryotes.

Q9JM59	KCIP2_RAT	Kv channel-interacting protein 2	12006572	Palmitoylation of KChIP splicing variants is required for efficient cell surface expression of Kv4.3 channels.

P13186	KIN2_YEAST	Serine/threonine-protein kinase KIN2	15563607	The yeast par-1 homologs kin1 and kin2 show genetic and physical interactions with components of the exocytic machinery.

P19474	RO52_HUMAN	E3 ubiquitin-protein ligase TRIM21	16316627	Oncogenic protein UnpEL/Usp4 deubiquitinates Ro52 by its isopeptidase activity.

P22354	RM20_YEAST	54S ribosomal protein L20, mitochondrial	12392552	Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components.

O00294	TULP1_HUMAN	Tubby-related protein 1	9462750	Recessive mutations in the gene encoding the tubby-like protein TULP1 in patients with retinitis pigmentosa.

Q8WXG9	GPR98_HUMAN	G-protein coupled receptor 98	10976914	Sequence similarities between a novel putative G protein-coupled receptor and Na+/Ca2+ exchangers define a cation binding domain.

Q9LHF1	LRX4_ARATH	Leucine-rich repeat extensin-like protein 4	16287169	Arabidopsis cell wall proteome defined using multidimensional protein identification technology.

O23403	PPD1_ARATH	PsbP domain-containing protein 1, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q08960	TYW1_YEAST	tRNA wybutosine-synthesizing protein 1	16162496	Discovery of a gene family critical to wyosine base formation in a subset of phenylalanine-specific transfer RNAs.

Q09892	HOG1_SCHPO	Mitogen-activated protein kinase sty1	15840944	Hsp16p is required for thermotolerance in nuclear mRNA export in fission yeast Schizosaccharomyces pombe.

Q8LC95	ENL3_ARATH	Early nodulin-like protein 3	12805588	Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis.

Q12361	GPR1_YEAST	G protein-coupled receptor GPR1	9524122	GPR1 encodes a putative G protein-coupled receptor that associates with the Gpa2p Galpha subunit and functions in a Ras-independent pathway.

Q9V8G0	IM03_DROME	Immune-induced peptide 3	9736738	Differential display of peptides induced during the immune response of Drosophila: a matrix-assisted laser desorption ionization time-of- flight mass spectrometry study.

Q04206	TF65_HUMAN	Transcription factor p65	1493333	I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding.

Q92793	CBP_HUMAN	CREB-binding protein	14716005	Dendrite development regulated by CREST, a calcium-regulated transcriptional activator.

Q9S7D1	DGDG1_ARATH	Digalactosyldiacylglycerol synthase 1, chloroplastic	11429410	The digalactosyldiacylglycerol (DGDG) synthase DGD1 is inserted into the outer envelope membrane of chloroplasts in a manner independent of the general import pathway and does not depend on direct interaction with monogalactosyldiacylglycerol synthase for DGDG biosynthesis.

Q8R2Z5	VWA1_MOUSE	von Willebrand factor A domain-containing protein 1	18757743	Transcriptome-based systematic identification of extracellular matrix proteins.

O54943	PER2_MOUSE	Period circadian protein homolog 2	9856465	Mammalian circadian autoregulatory loop: a timeless ortholog and mPer1 interact and negatively regulate CLOCK-BMAL1-induced transcription.

P23501	DS1P2_YEAST	Dihydrosphingosine 1-phosphate phosphatase YSR3	10477278	The dihydrosphingosine-1-phosphate phosphatases of Saccharomyces cerevisiae are important regulators of cell proliferation and heat stress responses.

P09052	VASA1_DROME	ATP-dependent RNA helicase vasa, isoform A	12479811	VASA localization requires the SPRY-domain and SOCS-box containing protein, GUSTAVUS.

P20965	PABPA_XENLA	Polyadenylate-binding protein 1-A	12489691	Characterization of the poly(A) binding proteins expressed during oogenesis and early development of Xenopus laevis.

Q9NQC3	RTN4_HUMAN	Reticulon-4	10667797	Identification of the Nogo inhibitor of axon regeneration as a Reticulon protein.

Q15528	MED22_HUMAN	Mediator of RNA polymerase II transcription subunit 22	8586415	Surf5: a gene in the tightly clustered mouse surfeit locus is highly conserved and transcribed divergently from the rpL7A (Surf3) gene.

Q9P246	STIM2_HUMAN	Stromal interaction molecule 2	18166150	Biophysical characterization of the EF-hand and SAM domain containing Ca2+ sensory region of STIM1 and STIM2.

Q9USM3	SFH1_SCHPO	Chromatin structure-remodeling complex subunit sfh1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9WTJ2	OVOL1_MOUSE	Putative transcription factor Ovo-like 1	9808631	The ovo gene required for cuticle formation and oogenesis in flies is involved in hair formation and spermatogenesis in mice.

P26368	U2AF2_HUMAN	Splicing factor U2AF 65 kDa subunit	1538748	Cloning and domain structure of the mammalian splicing factor U2AF.

Q9Y5Z0	BACE2_HUMAN	Beta-secretase 2	10591213	Membrane-anchored aspartyl protease with Alzheimer's disease beta- secretase activity.

P17980	PRS6A_HUMAN	26S protease regulatory subunit 6A	8419915	The type 1 human immunodeficiency virus Tat binding protein is a transcriptional activator belonging to an additional family of evolutionarily conserved genes.

Q923K9	A1CF_RAT	APOBEC1 complementation factor	10781591	Purification and molecular cloning of a novel essential component of the apolipoprotein B mRNA editing enzyme-complex.

P25445	TNR6_HUMAN	Tumor necrosis factor receptor superfamily member 6	1375228	Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen.

Q44337	FLIE_AGRT5	Flagellar hook-basal body complex protein fliE	9161424	Isolation and characterisation of a linked cluster of genes from Agrobacterium tumefaciens encoding proteins involved in flagellar basal-body structure.

Q9JKY5	HIP1R_MOUSE	Huntingtin-interacting protein 1-related protein	10613908	An actin-binding protein of the Sla2/Huntingtin interacting protein 1 family is a novel component of clathrin-coated pits and vesicles.

P01019	ANGT_HUMAN	Angiotensinogen	6089875	Primary structure of human preangiotensinogen deduced from the cloned cDNA sequence.

Q6NSN2	AOF_DANRE	Amine oxidase [flavin-containing]	16917825	Distinct structure and activity of monoamine oxidase in the brain of zebrafish (Danio rerio).

P04150	GCR_HUMAN	Glucocorticoid receptor	9590696	Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex.

Q99385	VCX1_YEAST	Vacuolar calcium ion transporter	8628289	Calcineurin inhibits VCX1-dependent H+/Ca2+ exchange and induces Ca2+ ATPases in Saccharomyces cerevisiae.

P0A9K9	SLYD_ECOLI	FKBP-type peptidyl-prolyl cis-trans isomerase slyD	19356587	NMR solution structure of SlyD from Escherichia coli: spatial separation of prolyl isomerase and chaperone function.

Q99873	ANM1_HUMAN	Protein arginine N-methyltransferase 1	10749851	Protein-arginine methyltransferase I, the predominant protein- arginine methyltransferase in cells, interacts with and is regulated by interleukin enhancer-binding factor 3.

Q11130	FUT7_HUMAN	Alpha-(1,3)-fucosyltransferase	8207002	Molecular cloning of a cDNA encoding a novel human leukocyte alpha- 1,3-fucosyltransferase capable of synthesizing the sialyl Lewis x determinant.

P03995	GFAP_MOUSE	Glial fibrillary acidic protein	17356066	Synemin is expressed in reactive astrocytes in neurotrauma and interacts differentially with vimentin and GFAP intermediate filament networks.

Q45FX5	VAV_CAEEL	Protein vav-1	16213217	The Rho/Rac family guanine nucleotide exchange factor VAV-1 regulates rhythmic behaviors in Caenorhabditis elegans.

Q968Y9	INSR_CAEEL	Insulin-like receptor	9252323	daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans.

Q7SZP9	APJA_DANRE	Apelin receptor A	17336906	The G protein-coupled receptor Agtrl1b regulates early development of myocardial progenitors.

O74553	DUS4_SCHPO	tRNA-dihydrouridine synthase 4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P84738	PAL1F_EUGGR	Photoactivated adenylate cyclase subunit alpha-like protein 1224-5/1F	16121285	Photoactivated adenylyl cyclase (PAC) genes in the flagellate Euglena gracilis mutant strains.

Q06520	ST2A1_HUMAN	Bile salt sulfotransferase	2268288	Human liver steroid sulphotransferase sulphates bile acids.

P61956	SUMO2_HUMAN	Small ubiquitin-related modifier 2	18408734	RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation.

O43159	RRP8_HUMAN	Ribosomal RNA-processing protein 8	18485871	Epigenetic control of rDNA loci in response to intracellular energy status.

Q00947	STP1_YEAST	Transcription factor STP1	1588961	STP1, a gene involved in pre-tRNA processing, encodes a nuclear protein containing zinc finger motifs.

P07510	ACHG_HUMAN	Acetylcholine receptor subunit gamma	3967651	Cloning and sequence analysis of human genomic DNA encoding gamma subunit precursor of muscle acetylcholine receptor.

Q9PU13	SPD1A_XENLA	Speedy protein 1-A	11730327	RINGO efficiently triggers meiosis resumption in mouse oocytes and induces cell cycle arrest in embryos.

Q9S7H8	ICS1_ARATH	Isochorismate synthase 1, chloroplastic	11734859	Isochorismate synthase is required to synthesize salicylic acid for plant defence.

P43378	PTN9_HUMAN	Tyrosine-protein phosphatase non-receptor type 9	19167335	Large-scale structural analysis of the classical human protein tyrosine phosphatome.

Q8GXR9	DHNA_ARATH	Probable NADH dehydrogenase, chloroplastic/mitochondrial	16258072	Characterization of mitochondrial alternative NAD(P)H dehydrogenases in Arabidopsis: intraorganelle location and expression.

P39551	PRM9_YEAST	Pheromone-regulated membrane protein 9	12925749	Suppression of coatomer mutants by a new protein family with COPI and COPII binding motifs in Saccharomyces cerevisiae.

P53040	TAF6_YEAST	Transcription initiation factor TFIID subunit 6	12446794	The novel SLIK histone acetyltransferase complex functions in the yeast retrograde response pathway.

Q8SX83	SPEN_DROME	Protein split ends	10704397	split ends encodes large nuclear proteins that regulate neuronal cell fate and axon extension in the Drosophila embryo.

Q94IG7	PPOCM_SPIOL	Protoporphyrinogen oxidase, chloroplastic/mitochondrial	11274159	Dual targeting of spinach protoporphyrinogen oxidase II to mitochondria and chloroplasts by alternative use of two in-frame initiation codons.

Q10294	PAC2_SCHPO	cAMP-independent regulatory protein pac2	8536311	Schizosaccharomyces pombe pac2+ controls the onset of sexual development via a pathway independent of the cAMP cascade.

Q94518	NACA_DROME	Nascent polypeptide-associated complex subunit alpha	15239960	Localization-dependent oskar protein accumulation; control after the initiation of translation.

Q9JMK2	KC1E_MOUSE	Casein kinase I isoform epsilon	19414593	Casein kinase 1 delta regulates the pace of the mammalian circadian clock.

Q03018	ESP1_YEAST	Separin	11149918	A novel role of the budding yeast separin Esp1 in anaphase spindle elongation: evidence that proper spindle association of Esp1 is regulated by Pds1.

Q9Y7U6	RGF1_SCHPO	Rho1 guanine nucleotide exchange factor 1	16421249	Rgf1p is a specific Rho1-GEF that coordinates cell polarization with cell wall biogenesis in fission yeast.

Q53079	PSB1_RHOER	Proteasome subunit beta 1	7583123	The first characterization of a eubacterial proteasome: the 20S complex of Rhodococcus.

P09605	KCRS_RAT	Creatine kinase S-type, mitochondrial	1859839	Structural characterization and tissue-specific expression of the mRNAs encoding isoenzymes from two rat mitochondrial creatine kinase genes.

P28321	YJU3_YEAST	Serine hydrolase YJU3	10515935	Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiae.

Q12948	FOXC1_HUMAN	Forkhead box protein C1	8499623	Drosophila forkhead homologues are expressed in a lineage-restricted manner in human hematopoietic cells.

Q9Y613	FHOD1_HUMAN	FH1/FH2 domain-containing protein 1	10352228	Identification and characterization of a protein containing formin homology (FH1/FH2) domains.

P15428	PGDH_HUMAN	15-hydroxyprostaglandin dehydrogenase [NAD+]	15574495	15-Hydroxyprostaglandin dehydrogenase, a COX-2 oncogene antagonist, is a TGF-beta-induced suppressor of human gastrointestinal cancers.

A8MQY1	NAC68_ARATH	NAC domain-containing protein 68	17098812	A membrane-bound NAC transcription factor regulates cell division in Arabidopsis.

P29295	HRR25_YEAST	Casein kinase I homolog HRR25	1495994	The budding yeast HRR25 gene product is a casein kinase I isoform.

Q60V73	GLYC_CAEBR	Serine hydroxymethyltransferase	10216251	Identification and characterization of a serine hydroxymethyltransferase isoform in Caenorhabditis briggsae.

Q92777	SYN2_HUMAN	Synapsin-2	8964517	Cloning and sequencing analysis of a human synapsin IIb-encoding brain cDNA.

Q9JMB1	THEG_MOUSE	Testicular haploid expressed gene protein	10747865	Insertional mutation of the murine kisimo locus caused a defect in spermatogenesis.

P01704	LV201_HUMAN	Ig lambda chain V-II region TOG	500108	Primary structure of cryo Bence-Jones protein (Tog) from the urine of a patient with IgD myeloma.

Q16236	NF2L2_HUMAN	Nuclear factor erythroid 2-related factor 2	7937919	Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF- E2/AP1 repeat of the beta-globin locus control region.

P51136	GSK3_DICDI	Glycogen synthase kinase-3	15342480	GSK3 is a multifunctional regulator of Dictyostelium development.

Q90Z80	FBX5A_XENLA	F-box only protein 5-A	11389834	EMI1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase-promoting complex.

P19524	MYO2_YEAST	Myosin-2	8188749	Immunofluorescence localization of the unconventional myosin, Myo2p, and the putative kinesin-related protein, Smy1p, to the same regions of polarized growth in Saccharomyces cerevisiae.

Q8R480	NUP85_MOUSE	Nuclear pore complex protein Nup85	15995708	Pivotal function for cytoplasmic protein FROUNT in CCR2-mediated monocyte chemotaxis.

P40072	SLX8_YEAST	E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX8	16325482	Suppression of genomic instability by SLX5 and SLX8 in Saccharomyces cerevisiae.

P15108	HSC82_YEAST	ATP-dependent molecular chaperone HSC82	14562095	Global analysis of protein localization in budding yeast.

Q04969	SPC2_YEAST	Signal peptidase complex subunit SPC2	8910564	Structurally related Spc1p and Spc2p of yeast signal peptidase complex are functionally distinct.

O88987	AKAP3_MOUSE	A-kinase anchor protein 3	10319321	Isolation and molecular characterization of AKAP110, a novel, sperm- specific protein kinase A-anchoring protein.

P32626	ENOPH_YEAST	Enolase-phosphatase E1	14562095	Global analysis of protein localization in budding yeast.

O14239	RAX2_SCHPO	Polarized growth protein rax2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q04600	TMA64_YEAST	Translation machinery-associated protein 64	16702403	Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes.

Q76IQ7	TOX2_RAT	TOX high mobility group box family member 2	14764631	Cloning and characterization of granulosa cell high-mobility group (HMG)-box protein-1, a novel HMG-box transcriptional regulator strongly expressed in rat ovarian granulosa cells.

Q91616	NDF1_XENLA	Neurogenic differentiation factor 1	15531363	Sequences downstream of the bHLH domain of the Xenopus hairy-related transcription factor-1 act as an extended dimerization domain that contributes to the selection of the partners.

P27637	BUD14_YEAST	Bud site selection protein 14	11452010	A genomic study of the bipolar bud site selection pattern in Saccharomyces cerevisiae.

Q9Y813	RPR2_SCHPO	Ribonuclease P protein subunit rpr2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O15265	ATX7_HUMAN	Ataxin-7	10441328	Nuclear localization of the spinocerebellar ataxia type 7 protein, ataxin-7.

Q9U2M7	AP4A_CAEEL	Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]	11738085	Cloning, characterisation and crystallisation of a diadenosine 5',5''-P(1),P(4)-tetraphosphate pyrophosphohydrolase from Caenorhabditis elegans.

Q92328	MDM12_YEAST	Mitochondrial distribution and morphology protein 12	13679517	A protein complex containing Mdm10p, Mdm12p, and Mmm1p links mitochondrial membranes and DNA to the cytoskeleton-based segregation machinery.

P42284	LOLA2_DROME	Longitudinals lacking protein, isoforms H/M/V	8050351	Lola encodes a putative transcription factor required for axon growth and guidance in Drosophila.

Q92796	DLG3_HUMAN	Disks large homolog 3	19118189	Preso, a novel PSD-95-interacting FERM and PDZ domain protein that regulates dendritic spine morphogenesis.

Q96HZ4	HES6_HUMAN	Transcription cofactor HES-6	10851137	The bHLH gene Hes6, an inhibitor of Hes1, promotes neuronal differentiation.

Q8N1H7	S6OS1_HUMAN	Protein SIX6OS1	15703187	Natural antisense transcripts associated with genes involved in eye development.

Q3E790	TSC3_YEAST	Serine palmitoyltransferase-regulating protein TSC3	10713067	Tsc3p is an 80-amino acid protein associated with serine palmitoyltransferase and required for optimal enzyme activity.

Q08209	PP2BA_HUMAN	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	11114196	Calsarcins, a novel family of sarcomeric calcineurin-binding proteins.

P62834	RAP1A_HUMAN	Ras-related protein Rap-1A	11022048	Regulation of a novel human phospholipase C, PLCepsilon, through membrane targeting by Ras.

Q7Z460	CLAP1_HUMAN	CLIP-associating protein 1	15631994	CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex.

O60356	NUPR1_HUMAN	Nuclear protein 1	10092851	Cloning and expression of the human p8, a nuclear protein with mitogenic activity.

P10633	CP2D1_RAT	Cytochrome P450 2D1	9434752	Expression of four rat CYP2D isoforms in Saccharomyces cerevisiae and their catalytic specificity.

Q61010	DTX1_MOUSE	Protein deltex-1	11226752	Murine homologs of deltex define a novel gene family involved in vertebrate Notch signaling and neurogenesis.

Q86Z14	KLOTB_HUMAN	Beta-klotho	18829467	C-terminal tail of FGF19 determines its specificity toward Klotho co- receptors.

P26188	MGMT_YEAST	Methylated-DNA--protein-cysteine methyltransferase	2065659	Primary sequence and biological functions of a Saccharomyces cerevisiae O6-methylguanine/O4-methylthymine DNA repair methyltransferase gene.

P56968	PYRK_LACLM	Dihydroorotate dehydrogenase electron transfer subunit	11188687	Structure of dihydroorotate dehydrogenase B: electron transfer between two flavin groups bridged by an iron-sulphur cluster.

Q13546	RIPK1_HUMAN	Receptor-interacting serine/threonine-protein kinase 1	10521396	Cleavage of the death domain kinase RIP by caspase-8 prompts TNF- induced apoptosis.

Q96DC9	OTUB2_HUMAN	Ubiquitin thioesterase OTUB2	15258613	Crystal structure of human otubain 2.

Q38912	RAC3_ARATH	Rac-like GTP-binding protein ARAC3	10798620	Localization of AtROP4 and AtROP6 and interaction with the guanine nucleotide dissociation inhibitor AtRhoGDI1 from Arabidopsis.

P17157	PHO85_YEAST	Cyclin-dependent protein kinase PHO85	7973731	The PCL2 (ORFD)-PHO85 cyclin-dependent kinase complex: a cell cycle regulator in yeast.

P22082	SNF2_YEAST	Transcription regulatory protein SNF2	1901413	Functional interdependence of the yeast SNF2, SNF5, and SNF6 proteins in transcriptional activation.

P25799	NFKB1_MOUSE	Nuclear factor NF-kappa-B p105 subunit	11931770	Peptide-induced negative selection of thymocytes activates transcription of an NF-kappa B inhibitor.

Q9LY14	MSRA3_ARATH	Peptide methionine sulfoxide reductase A3	17031545	Plant methionine sulfoxide reductase A and B multigenic families.

O60755	GALR3_HUMAN	Galanin receptor type 3	9722565	Cloned human and rat galanin GALR3 receptors: pharmacology and activation of G-protein inwardly rectifying K+ channels.

Q9UJ83	HACL1_HUMAN	2-hydroxyacyl-CoA lyase 1	10468558	Purification, molecular cloning, and expression of 2- hydroxyphytanoyl-CoA lyase, a peroxisomal thiamine hydrophosphate- dependent enzyme that catalyzes the carbon-carbon bond cleavage during alpha-oxidation of 3-methyl-branched fatty acids.

P58962	GR58A_DROME	Putative gustatory receptor 58a	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

Q15649	ZNHI3_HUMAN	Zinc finger HIT domain-containing protein 3	7776974	Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor.

Q12933	TRAF2_HUMAN	TNF receptor-associated factor 2	8069916	A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor.

O00748	EST2_HUMAN	Carboxylesterase 2	9144407	Molecular cloning and characterization of a novel putative carboxylesterase, present in human intestine and liver.

P0AE06	ACRA_ECOLI	Acriflavine resistance protein A	8407802	Molecular cloning and characterization of acrA and acrE genes of Escherichia coli.

P39429	TRAF2_MOUSE	TNF receptor-associated factor 2	18849341	FLN29 deficiency reveals its negative regulatory role in the Toll- like receptor (TLR) and retinoic acid-inducible gene I (RIG-I)-like helicase signaling pathway.

Q08004	BUD20_YEAST	Bud site selection protein 20	11452010	A genomic study of the bipolar bud site selection pattern in Saccharomyces cerevisiae.

Q9UI47	CTNA3_HUMAN	Catenin alpha-3	11590244	AlphaT-catenin: a novel tissue-specific beta-catenin-binding protein mediating strong cell-cell adhesion.

Q80W94	MOGT2_MOUSE	2-acylglycerol O-acyltransferase 2	12576479	Cloning and functional characterization of a mouse intestinal acyl- CoA:monoacylglycerol acyltransferase, MGAT2.

O94513	EIF3E_SCHPO	Eukaryotic translation initiation factor 3 subunit E	15904532	PCI proteins eIF3e and eIF3m define distinct translation initiation factor 3 complexes.

P24783	DBP2_YEAST	ATP-dependent RNA helicase DBP2	7883168	Identification of a novel component of the nonsense-mediated mRNA decay pathway by use of an interacting protein screen.

Q12464	RUVB2_YEAST	RuvB-like protein 2	14690608	A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1.

P41814	TRM6_YEAST	tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6	10779558	The Gcd10p/Gcd14p complex is the essential two-subunit tRNA(1- methyladenosine) methyltransferase of Saccharomyces cerevisiae.

Q9V3G3	PPIE_DROME	Peptidyl-prolyl cis-trans isomerase E	11976948	A new family of cyclophilins with an RNA recognition motif that interact with members of the trx/MLL protein family in Drosophila and human cells.

P36655	DSBD_ECOLI	Thiol:disulfide interchange protein dsbD	7957865	Specific thiol compounds complement deficiency in c-type cytochrome biogenesis in Escherichia coli carrying a mutation in a membrane-bound disulphide isomerase-like protein.

Q9Y7U5	RGF3_SCHPO	Rho1 guanine nucleotide exchange factor 3	16291723	Cell wall remodeling at the fission yeast cell division site requires the Rho-GEF Rgf3p.

Q9HDY1	ASE1_SCHPO	Anaphase spindle elongation protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q13423	NNTM_HUMAN	NAD(P) transhydrogenase, mitochondrial	9524818	Cloning and deduced amino acid sequence of human nicotinamide nucleotide transhydrogenase.

P04637	P53_HUMAN	Cellular tumor antigen p53	11672523	hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase.

Q96TL7	RAP1_SCHPO	DNA-binding protein rap1	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

P54136	SYRC_HUMAN	Arginyl-tRNA synthetase, cytoplasmic	16055448	The C-terminal appended domain of human cytosolic leucyl-tRNA synthetase is indispensable in its interaction with arginyl-tRNA synthetase in the multi-tRNA synthetase complex.

P53727	BUD17_YEAST	Putative pyridoxal kinase BUD17	11452010	A genomic study of the bipolar bud site selection pattern in Saccharomyces cerevisiae.

Q00961	NMDE3_RAT	Glutamate [NMDA] receptor subunit epsilon-3	8428958	Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits.

P28519	RAD14_YEAST	DNA repair protein RAD14	8621533	Nucleotide excision repair in yeast is mediated by sequential assembly of repair factors and not by a pre-assembled repairosome.

O96099	FAD5B_DICDI	Delta(5) fatty acid desaturase B	10712614	A second functional Delta5 fatty acid desaturase in the cellular slime mould Dictyostelium discoideum.

Q55DM1	LVSA_DICDI	BEACH domain-containing protein lvsA	15086784	Structure-function analysis of the BEACH protein LvsA.

Q18775	DOPR4_CAEEL	Dopamine receptor 4	16001968	Characterization of a novel D2-like dopamine receptor with a truncated splice variant and a D1-like dopamine receptor unique to invertebrates from Caenorhabditis elegans.

O94441	YPP1_SCHPO	Putative cargo-transport protein ypp1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8IY92	SLX4_HUMAN	Structure-specific endonuclease subunit SLX4	19596235	Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair.

Q8N5M1	ATPF2_HUMAN	ATP synthase mitochondrial F1 complex assembly factor 2	11410595	Atp11p and Atp12p are assembly factors for the F(1)-ATPase in human mitochondria.

Q6QZN6	DACT1_DANRE	Dapper homolog 1	15539487	Zebrafish Dapper1 and Dapper2 play distinct roles in Wnt-mediated developmental processes.

Q9VS97	PGPSD_DROME	Peptidoglycan-recognition protein SD	11106397	A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster.

P85045	LYS_BUFAN	Lysozyme C	16309969	Purification of a lysozyme from skin secretions of Bufo andrewsi.

P82873	TO202_ARATH	Mitochondrial import receptor subunit TOM20-2	11161051	Purification and characterization of the preprotein translocase of the outer mitochondrial membrane from Arabidopsis. Identification of multiple forms of TOM20.

Q99ME6	AT1B4_MOUSE	Protein ATP1B4	14656723	Accumulation of beta (m), a structural member of X,K-ATPase beta- subunit family, in nuclear envelopes of perinatal myocytes.

O95396	MOCS3_HUMAN	Adenylyltransferase and sulfurtransferase MOCS3	19017811	A functional proteomics approach links the ubiquitin-related modifier Urm1 to a tRNA modification pathway.

P42262	GRIA2_HUMAN	Glutamate receptor 2	8003671	Primary structure and functional expression of the AMPA/kainate receptor subunit 2 from human brain.

Q8IR79	LIMK1_DROME	LIM domain kinase 1	15220930	LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1.

Q9VQM4	TYDP1_DROME	Probable tyrosyl-DNA phosphodiesterase	15556867	glaikit is essential for the formation of epithelial polarity and neuronal development.

Q8VYZ0	ORTH2_ARATH	E3 ubiquitin-protein ligase ORTHRUS 2	17239600	The SRA methyl-cytosine-binding domain links DNA and histone methylation.

Q5ABD0	SNF7_CANAL	Vacuolar-sorting protein SNF7	15590834	Snf7p, a component of the ESCRT-III protein complex, is an upstream member of the RIM101 pathway in Candida albicans.

Q86VP1	TAXB1_HUMAN	Tax1-binding protein 1	10435631	The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases.

O14641	DVL2_HUMAN	Segment polarity protein dishevelled homolog DVL-2	11742073	beta-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins.

P40855	PEX19_HUMAN	Peroxisomal biogenesis factor 19	11883941	Two splice variants of human PEX19 exhibit distinct functions in peroxisomal assembly.

Q9ERS2	NDUAD_MOUSE	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	10924506	Identification of GRIM-19, a novel cell death-regulatory gene induced by the interferon-beta and retinoic acid combination, using a genetic approach.

Q01722	GCR2_YEAST	Glycolytic genes transcriptional activator GCR2	1508187	Role of GCR2 in transcriptional activation of yeast glycolytic genes.

Q9VW47	MED12_DROME	Mediator of RNA polymerase II transcription subunit 12	17290221	Distinct roles for Mediator Cdk8 module subunits in Drosophila development.

P12268	IMDH2_HUMAN	Inosine-5'-monophosphate dehydrogenase 2	1969416	Two distinct cDNAs for human IMP dehydrogenase.

Q9R1T5	ACY2_RAT	Aspartoacylase	16935940	Aspartoacylase is a regulated nuclear-cytoplasmic enzyme.

Q07953	SDO1_YEAST	Ribosome maturation protein SDO1	14690591	Assigning function to yeast proteins by integration of technologies.

O60086	ILV6_SCHPO	Probable acetolactate synthase small subunit	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O14737	PDCD5_HUMAN	Programmed cell death protein 5	9920759	TFAR19, a novel apoptosis-related gene cloned from human leukemia cell line TF-1, could enhance apoptosis of some tumor cells induced by growth factor withdrawal.

P53220	TIM21_YEAST	Mitochondrial import inner membrane translocase subunit TIM21	14562095	Global analysis of protein localization in budding yeast.

P38836	ECM14_YEAST	Protein ECM14	14562095	Global analysis of protein localization in budding yeast.

Q9U8W7	TL5B_TACTR	Techylectin-5B	10468566	Horseshoe crab acetyl group-recognizing lectins involved in innate immunity are structurally related to fibrinogen.

O75643	U520_HUMAN	U5 small nuclear ribonucleoprotein 200 kDa helicase	8670905	The HeLa 200 kDa U5 snRNP-specific protein and its homologue in Saccharomyces cerevisiae are members of the DEXH-box protein family of putative RNA helicases.

Q61839	ANFC_MOUSE	C-type natriuretic peptide	8897953	Isolation, mapping, and regulated expression of the gene encoding mouse C-type natriuretic peptide.

Q99ME7	TBX19_MOUSE	T-box transcription factor TBX19	11447259	Tbx19, a tissue-selective regulator of POMC gene expression.

Q9Y6W8	ICOS_HUMAN	Inducible T-cell costimulator	9930702	ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28.

O14296	VPS24_SCHPO	Vacuolar protein sorting-associated protein 24	17660439	Essential roles of class E Vps proteins for sorting into multivesicular bodies in Schizosaccharomyces pombe.

Q9UBS8	RNF14_HUMAN	E3 ubiquitin-protein ligase RNF14	19345326	Regulation of androgen receptor transcriptional activity and specificity by RNF6-induced ubiquitination.

Q15303	ERBB4_HUMAN	Receptor tyrosine-protein kinase erbB-4	19561640	WW domain containing E3 ubiquitin protein ligase 1 targets the full- length ErbB4 for ubiquitin-mediated degradation in breast cancer.

P25635	PWP2_YEAST	Periodic tryptophan protein 2	12068309	A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis.

P33018	SFGH2_ECOLI	S-formylglutathione hydrolase yeiG	16567800	Molecular basis of formaldehyde detoxification. Characterization of two S-formylglutathione hydrolases from Escherichia coli, FrmB and YeiG.

Q9FKG3	K6PF4_ARATH	6-phosphofructokinase 4, chloroplastic	17485088	Characterisation of the ATP-dependent phosphofructokinase gene family from Arabidopsis thaliana.

P21675	TAF1_HUMAN	Transcription initiation factor TFIID subunit 1	7680771	Cloning and expression of human TAFII250: a TBP-associated factor implicated in cell-cycle regulation.

Q9P6Q6	CET1_SCHPO	mRNA-capping enzyme subunit beta	12788946	Homodimeric quaternary structure is required for the in vivo function and thermal stability of Saccharomyces cerevisiae and Schizosaccharomyces pombe RNA triphosphatases.

Q0QWG9	GRD2I_MOUSE	Delphilin	16168524	Identification and characterization of a novel Delphilin variant with an alternative N-terminus.

P62623	ISPH_ECOLI	4-hydroxy-3-methylbut-2-enyl diphosphate reductase	12571359	The deoxyxylulose phosphate pathway of isoprenoid biosynthesis: studies on the mechanisms of the reactions catalyzed by IspG and IspH protein.

Q96KS0	EGLN2_HUMAN	Egl nine homolog 2	11595184	C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation.

O88413	TULP3_MOUSE	Tubby-related protein 3	19286674	Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling.

Q9JLI7	SPAG6_MOUSE	Sperm-associated antigen 6	15827353	Dissecting the axoneme interactome: the mammalian orthologue of Chlamydomonas PF6 interacts with sperm-associated antigen 6, the mammalian orthologue of Chlamydomonas PF16.

P52420	PUR2_ARATH	Phosphoribosylamine--glycine ligase, chloroplastic	7920700	Molecular characterization of Arabidopsis thaliana cDNAs encoding three purine biosynthetic enzymes.

P53632	PAP2_YEAST	Poly(A) RNA polymerase protein 2	15935759	Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase.

P32263	P5CR_YEAST	Pyrroline-5-carboxylate reductase	1508147	ore2, a mutation affecting proline biosynthesis in the yeast Saccharomyces cerevisiae, leads to a cdc phenotype.

P92953	ATHB4_ARATH	Homeobox-leucine zipper protein ATHB-4	8106086	The Arabidopsis Athb-2 and -4 genes are strongly induced by far-red- rich light.

Q9ZVD0	SRRT_ARATH	Serrate RNA effector molecule	16222298	SERRATE coordinates shoot meristem function and leaf axial patterning in Arabidopsis.

Q13112	CAF1B_HUMAN	Chromatin assembly factor 1 subunit B	9614144	Nucleosome assembly activity and intracellular localization of human CAF-1 changes during the cell division cycle.

Q15311	RBP1_HUMAN	RalA-binding protein 1	11437348	RLIP76 is the major ATP-dependent transporter of glutathione- conjugates and doxorubicin in human erythrocytes.

Q01638	ILRL1_HUMAN	Interleukin-1 receptor-like 1	1482686	Nucleotide sequence of a complementary DNA for human ST2.

Q5GIT4	VGFR2_DANRE	Vascular endothelial growth factor receptor 2	17698971	Duplicate VegfA genes and orthologues of the KDR receptor tyrosine kinase family mediate vascular development in the zebrafish.

Q6IMN8	ALRA_DICDI	Aldose reductase A	14551196	Disruption of aldehyde reductase increases group size in dictyostelium.

P08243	ASNS_HUMAN	Asparagine synthetase [glutamine-hydrolyzing]	2573597	The N-terminal cysteine of human asparagine synthetase is essential for glutamine-dependent activity.

Q12142	ATG9_YEAST	Autophagy-related protein 9	10662773	Apg9p/Cvt7p is an integral membrane protein required for transport vesicle formation in the Cvt and autophagy pathways.

O74426	PPK33_SCHPO	Serine/threonine-protein kinase ppk33	15821139	Systematic deletion analysis of fission yeast protein kinases.

O04197	COI1_ARATH	Coronatine-insensitive protein 1	12445118	COI1 links jasmonate signalling and fertility to the SCF ubiquitin- ligase complex in Arabidopsis.

P07283	PMM_YEAST	Phosphomannomutase	3288631	The yeast SEC53 gene encodes phosphomannomutase.

Q9CRB3	HIUH_MOUSE	5-hydroxyisourate hydrolase	16462750	Completing the uric acid degradation pathway through phylogenetic comparison of whole genomes.

P08069	IGF1R_HUMAN	Insulin-like growth factor 1 receptor	15878855	{beta}-Arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth factor-1 receptor by acting as adaptor for the MDM2 E3 ligase.

Q9Y048	DTN1_CAEEL	Dystrobrevin-1	12062255	Overexpression of dystrobrevin delays locomotion defects and muscle degeneration in a dystrophin-deficient Caenorhabditis elegans.

O95793	STAU1_HUMAN	Double-stranded RNA-binding protein Staufen homolog 1	10022909	Mammalian Staufen is a double-stranded-RNA- and tubulin-binding protein which localizes to the rough endoplasmic reticulum.

Q12344	GYP5_YEAST	GTPase-activating protein GYP5	15802519	Interaction of the Saccharomyces cerevisiae cortical actin patch protein Rvs167p with proteins involved in ER to Golgi vesicle trafficking.

P02870	LEC_LENCU	Lectin	7592736	NMR, molecular modeling, and crystallographic studies of lentil lectin-sucrose interaction.

Q03957	CTK1_YEAST	CTD kinase subunit alpha	17545469	The RNA polymerase II CTD kinase Ctk1 functions in translation elongation.

Q9ZR03	UCRIA_ARATH	Cytochrome b6-f complex iron-sulfur subunit, chloroplastic	12040099	Tissue-specific, light-regulated and plastid-regulated expression of the single-copy nuclear gene encoding the chloroplast Rieske FeS protein of Arabidopsis thaliana.

Q9P3B1	YIL2_SCHPO	Putative Rho GTPase-activating protein C1565.02c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9FYL3	ALB31_ARATH	ALBINO3-like protein 1, chloroplastic	16595657	A second thylakoid membrane-localized Alb3/OxaI/YidC homologue is involved in proper chloroplast biogenesis in Arabidopsis thaliana.

Q62083	PICK1_MOUSE	PRKCA-binding protein	9405395	Specific interaction of the PDZ domain protein PICK1 with the COOH terminus of protein kinase C-alpha.

P34043	GPA5_DICDI	Guanine nucleotide-binding protein alpha-5 subunit	8620848	Mutations in the Dictyostelium heterotrimeric G protein alpha subunit G alpha5 alter the kinetics of tip morphogenesis.

Q07688	YPD1_YEAST	Phosphorelay intermediate protein YPD1	14656441	The yeast YPD1/SLN1 complex: insights into molecular recognition in two-component signaling systems.

O81123	ZIP1_ARATH	Zinc transporter 1	9618566	Identification of a family of zinc transporter genes from Arabidopsis that respond to zinc deficiency.

P10721	KIT_HUMAN	Mast/stem cell growth factor receptor	1717985	Mutation of the KIT (mast/stem cell growth factor receptor) protooncogene in human piebaldism.

P40484	MOB1_YEAST	DBF2 kinase activator protein MOB1	11404483	Protein kinase Cdc15 activates the Dbf2-Mob1 kinase complex.

Q9Y6N7	ROBO1_HUMAN	Roundabout homolog 1	9608531	The DUTT1 gene, a novel NCAM family member is expressed in developing murine neural tissues and has an unusually broad pattern of expression.

P13010	XRCC5_HUMAN	X-ray repair cross-complementing protein 5	7957065	Human DNA helicase II: a novel DNA unwinding enzyme identified as the Ku autoantigen.

P27169	PON1_HUMAN	Serum paraoxonase/arylesterase 1	1657140	Characterization of cDNA clones encoding rabbit and human serum paraoxonase: the mature protein retains its signal sequence.

O14802	RPC1_HUMAN	DNA-directed RNA polymerase III subunit RPC1	9331371	The largest subunit of human RNA polymerase III is closely related to the largest subunit of yeast and trypanosome RNA polymerase III.

Q06510	TAZ1_YEAST	Lysophosphatidylcholine acyltransferase	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q8I480	ZNRF2_PLAF7	RING finger protein PFE0100w	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

Q42404	RU17_ARATH	U1 small nuclear ribonucleoprotein 70 kDa	8776903	Structure and expression of a plant U1 snRNP 70K gene: alternative splicing of U1 snRNP 70K pre-mRNAs produces two different transcripts.

Q80Z25	OFD1_MOUSE	Oral-facial-digital syndrome 1 protein homolog	20230748	Ofd1, a human disease gene, regulates the length and distal structure of centrioles.

O88310	ITL1A_MOUSE	Intelectin-1a	16866365	Intelectin: a novel lipid raft-associated protein in the enterocyte brush border.

Q9W3W5	WIF1_DROME	Protein shifted	15691765	The Drosophila ortholog of the human wnt inhibitor factor shifted controls the diffusion of lipid-modified hedgehog.

Q15853	USF2_HUMAN	Upstream stimulatory factor 2	1589769	Interaction cloning: identification of a helix-loop-helix zipper protein that interacts with c-Fos.

Q9WVF9	CLC2I_MOUSE	C-type lectin domain family 2 member I	15963483	C-type lectin OCILRP2/Clr-g and its ligand NKRP1f costimulate T cell proliferation and IL-2 production.

Q3URD3	SLMAP_MOUSE	Sarcolemmal membrane-associated protein	10986292	Alternative splicing, expression, and genomic structure of the 3' region of the gene encoding the sarcolemmal-associated proteins (SLAPs) defines a novel class of coiled-coil tail-anchored membrane proteins.

P98192	GNPAT_MOUSE	Dihydroxyacetone phosphate acyltransferase	10456321	Synthesis of plasmalogens in eye lens epithelial cells.

P55347	PKNX1_HUMAN	Homeobox protein PKNOX1	9479508	PKNOX1, a gene encoding PREP1, a new regulator of Pbx activity, maps on human chromosome 21q22.3 and murine chromosome 17B/C.

P47025	MDV1_YEAST	Mitochondrial division protein 1	11038180	Gag3p, an outer membrane protein required for fission of mitochondrial tubules.

Q9BZC7	ABCA2_HUMAN	ATP-binding cassette sub-family A member 2	11178988	Complete coding sequence, promoter region, and genomic structure of the human ABCA2 gene and evidence for sterol-dependent regulation in macrophages.

Q80VL0	ICEF1_RAT	Interactor protein for cytohesin exchange factors 1	12920129	Interaction protein for cytohesin exchange factors 1 (IPCEF1) binds cytohesin 2 and modifies its activity.

O15047	SET1A_HUMAN	Histone-lysine N-methyltransferase SETD1A	17355966	Identification and characterization of the human Set1B histone H3- Lys4 methyltransferase complex.

Q92793	CBP_HUMAN	CREB-binding protein	15075319	Positive and negative modulation of the transcriptional activity of the ETS factor ESE-1 through interaction with p300, CREB-binding protein, and Ku 70/86.

Q75JR3	IDHC_DICDI	Isocitrate dehydrogenase [NADP] cytoplasmic	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q08465	YNG1_YEAST	Protein YNG1	12077334	Yng1p modulates the activity of Sas3p as a component of the yeast NuA3 Hhistone acetyltransferase complex.

P17654	AMY1_ORYSJ	Alpha-amylase	2102847	Classification and characterization of the rice alpha-amylase multigene family.

Q12463	TRM11_YEAST	tRNA guanosine-2'-O-methyltransferase TRM11	15899842	Trm11p and Trm112p are both required for the formation of 2- methylguanosine at position 10 in yeast tRNA.

Q86L04	TRAP1_DICDI	TNF receptor-associated protein 1 homolog, mitochondrial	15507488	Translocation of the Dictyostelium TRAP1 homologue to mitochondria induces a novel prestarvation response.

O94916	NFAT5_HUMAN	Nuclear factor of activated T-cells 5	10377394	NFAT5, a constitutively nuclear NFAT protein that does not cooperate with Fos and Jun.

Q9P2I0	CPSF2_HUMAN	Cleavage and polyadenylation specificity factor subunit 2	18688255	Conserved motifs in both CPSF73 and CPSF100 are required to assemble the active endonuclease for histone mRNA 3'-end maturation.

Q28068	CALI_BOVIN	Calicin	7641791	Molecular nature of calicin, a major basic protein of the mammalian sperm head cytoskeleton.

Q12493	NKP1_YEAST	Central kinetochore subunit NKP1	12408861	Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase Ipl1p.

O13600	SWS1_SCHPO	Zinc finger SWIM domain-containing protein sws1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NR56	MBNL1_HUMAN	Muscleblind-like protein 1	16946708	Interaction of muscleblind, CUG-BP1 and hnRNP H proteins in DM1- associated aberrant IR splicing.

O82390	ANTR1_ARATH	Sodium-dependent phosphate transport protein 1, chloroplastic	18086223	Functional analysis of the Arabidopsis PHT4 family of intracellular phosphate transporters.

P0AC16	FOLB_ECOLI	Dihydroneopterin aldolase	9651328	Biosynthesis of pteridines in Escherichia coli. Structural and mechanistic similarity of dihydroneopterin-triphosphate epimerase and dihydroneopterin aldolase.

P90901	IFA1_CAEEL	Intermediate filament protein ifa-1	14529618	In vivo and in vitro evidence that the four essential intermediate filament (IF) proteins A1, A2, A3 and B1 of the nematode Caenorhabditis elegans form an obligate heteropolymeric IF system.

Q15172	2A5A_HUMAN	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform	16541025	Shugoshin collaborates with protein phosphatase 2A to protect cohesin.

Q09161	NCBP1_HUMAN	Nuclear cap-binding protein subunit 1	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

Q24573	DRI_DROME	Protein dead ringer	11867548	The structure of the Dead ringer-DNA complex reveals how AT-rich interaction domains (ARIDs) recognize DNA.

Q9WVL0	MAAI_MOUSE	Maleylacetoacetate isomerase	10373324	Gene structure, chromosomal location, and expression pattern of maleylacetoacetate isomerase.

Q9ZWS9	ARR3_ARATH	Two-component response regulator ARR3	9662428	Expression of Arabidopsis response regulator homologs is induced by cytokinins and nitrate.

P22219	VPS15_YEAST	Serine/threonine-protein kinase VPS15	11157979	Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae.

O75146	HIP1R_HUMAN	Huntingtin-interacting protein 1-related protein	14732715	HIP1 and HIP1r stabilize receptor tyrosine kinases and bind 3- phosphoinositides via epsin N-terminal homology domains.

O74563	BRL2_SCHPO	E3 ubiquitin-protein ligase brl2	17374714	Ubiquitylation of histone H2B controls RNA polymerase II transcription elongation independently of histone H3 methylation.

P39001	UME6_YEAST	Transcriptional regulatory protein UME6	16314178	Stable incorporation of sequence specific repressors Ash1 and Ume6 into the Rpd3L complex.

Q24040	BGB_DROME	Protein big brother	8622696	Drosophila homologs of the proto-oncogene product PEBP2/CBF beta regulate the DNA-binding properties of Runt.

Q8STE5	CED12_CAEEL	Cell death abnormality protein 12	11703940	C. elegans CED-12 acts in the conserved crkII/DOCK180/Rac pathway to control cell migration and cell corpse engulfment.

P51451	BLK_HUMAN	Tyrosine-protein kinase Blk	7845672	Molecular cloning and chromosomal localization of the human homologue of a B-lymphocyte specific protein tyrosine kinase (blk).

P29353	SHC1_HUMAN	SHC-transforming protein 1	7559478	Distinct modes of interaction of SHC and insulin receptor substrate-1 with the insulin receptor NPEY region via non-SH2 domains.

Q12951	FOXI1_HUMAN	Forkhead box protein I1	7957066	Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending.

Q969J5	I22R2_HUMAN	Interleukin-22 receptor subunit alpha-2	11390453	Cloning and characterization of IL-22 binding protein, a natural antagonist of IL-10-related T cell-derived inducible factor/IL-22.

Q9FI23	DEF16_ARATH	Defensin-like protein 16	9001391	ESTs reveal a multigene family for plant defensins in Arabidopsis thaliana.

Q9UUC7	CTU2_SCHPO	Cytoplasmic tRNA 2-thiolation protein 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8LGH4	CUL4_ARATH	Cullin-4	20061554	Arabidopsis CULLIN4-damaged DNA binding protein 1 interacts with CONSTITUTIVELY PHOTOMORPHOGENIC1-SUPPRESSOR OF PHYA complexes to regulate photomorphogenesis and flowering time.

P32605	RU1A_YEAST	U1 small nuclear ribonucleoprotein A	8449403	An enhancer screen identifies a gene that encodes the yeast U1 snRNP A protein: implications for snRNP protein function in pre-mRNA splicing.

Q8IZP9	GPR64_HUMAN	G-protein coupled receptor 64	12420295	HE6, a two-subunit heptahelical receptor associated with apical membranes of efferent and epididymal duct epithelia.

P39938	RS26A_YEAST	40S ribosomal protein S26-A	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

P25641	ATG15_YEAST	Putative lipase ATG15	12499386	Intravacuolar membrane lysis in Saccharomyces cerevisiae. Does vacuolar targeting of Cvt17/Aut5p affect its function?

Q86IV5	CTNA_DICDI	Countin-1	12912898	CF45-1, a secreted protein which participates in Dictyostelium group size regulation.

Q683C9	AUR2_ARATH	Serine/threonine-protein kinase Aurora-2	15722465	Identification and dynamics of two classes of aurora-like kinases in Arabidopsis and other plants.

Q99551	MTERF_HUMAN	Transcription termination factor, mitochondrial	9118945	The human mitochondrial transcription termination factor (mTERF) is a multizipper protein but binds to DNA as a monomer, with evidence pointing to intramolecular leucine zipper interactions.

Q6SIF1	CRED_EMENI	HECT-type ubiquitin ligase-interacting protein creD	15255903	A role for creD, a carbon catabolite repression gene from Aspergillus nidulans, in ubiquitination.

O94289	LUB1_SCHPO	Ubiquitin homeostasis protein lub1	14993272	Lub1 participates in ubiquitin homeostasis and stress response via maintenance of cellular ubiquitin contents in fission yeast.

P41933	ODR7_CAEEL	Nuclear hormone receptor family member odr-7	11546744	The lin-11 LIM homeobox gene specifies olfactory and chemosensory neuron fates in C. elegans.

Q9NPB3	CABP2_HUMAN	Calcium-binding protein 2	10625670	Five members of a novel Ca(2+)-binding protein (CABP) subfamily with similarity to calmodulin.

Q9R244	TRPC2_MOUSE	Short transient receptor potential channel 2	10998353	Cloning, expression and subcellular localization of two novel splice variants of mouse transient receptor potential channel 2.

Q08954	YP199_YEAST	Smr domain-containing protein YPL199C	14562095	Global analysis of protein localization in budding yeast.

Q61686	CBX5_MOUSE	Chromobox protein homolog 5	10562550	Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family.

P23643	VPS3_YEAST	Vacuolar protein sorting-associated protein 3	2202738	Molecular analysis of the yeast VPS3 gene and the role of its product in vacuolar protein sorting and vacuolar segregation during the cell cycle.

O08697	ARL2_RAT	ADP-ribosylation factor-like protein 2	9208929	An ADP-ribosylation-factor(ARF)-like protein involved in regulated secretion.

Q9M8Y0	SEC_ARATH	Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SEC	12136030	Two O-linked N-acetylglucosamine transferase genes of Arabidopsis thaliana L. Heynh. have overlapping functions necessary for gamete and seed development.

P56206	SYG_THET8	Glycyl-tRNA synthetase	10064708	Glycyl-tRNA synthetase uses a negatively charged pit for specific recognition and activation of glycine.

Q00664	NUDF_EMENI	Nuclear distribution protein nudF	10931877	The LIS1-related NUDF protein of Aspergillus nidulans interacts with the coiled-coil domain of the NUDE/RO11 protein.

Q63262	PO3F3_RAT	POU domain, class 3, transcription factor 3	9405434	Redundancy of class III POU proteins in the oligodendrocyte lineage.

P43246	MSH2_HUMAN	DNA mismatch repair protein Msh2	11427529	The interaction of DNA mismatch repair proteins with human exonuclease I.

P20226	TBP_HUMAN	TATA-box-binding protein	11438666	The TFIID components human TAFII140 and Drosophila BIP2 (TAFII155) are novel metazoan homologues of yeast TAFII47 containing a histone fold and a PHD finger.

O22476	BRI1_ARATH	Protein BRASSINOSTEROID INSENSITIVE 1	19124768	Tyrosine phosphorylation of the BRI1 receptor kinase emerges as a component of brassinosteroid signaling in Arabidopsis.

Q54U75	CRLA_DICDI	Cyclic AMP receptor-like protein A	14732403	A cAMP receptor-like G protein-coupled receptor with roles in growth regulation and development.

Q9VGH1	CP315_DROME	Cytochrome P450 315a1, mitochondrial	14610274	Shade is the Drosophila P450 enzyme that mediates the hydroxylation of ecdysone to the steroid insect molting hormone 20- hydroxyecdysone.

Q9NSC2	SALL1_HUMAN	Sal-like protein 1	9425907	Mutations in the SALL1 putative transcription factor gene cause Townes-Brocks syndrome.

Q54H38	ABHD_DICDI	Abhydrolase domain-containing protein	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P11586	C1TC_HUMAN	C-1-tetrahydrofolate synthase, cytoplasmic	3053686	Primary structure of a human trifunctional enzyme. Isolation of a cDNA encoding methylenetetrahydrofolate dehydrogenase- methenyltetrahydrofolate cyclohydrolase-formyltetrahydrofolate synthetase.

Q8LQ74	IAA6_ORYSJ	Auxin-responsive protein IAA6	16200395	Structure and expression analysis of early auxin-responsive Aux/IAA gene family in rice (Oryza sativa).

Q17353	PAR3_CAEEL	Partitioning defective protein 3	15151982	PAR-3 is required for epithelial cell polarity in the distal spermatheca of C. elegans.

Q9Z1S8	GAB2_MOUSE	GRB2-associated-binding protein 2	15750601	The molecular scaffold Gab2 is a crucial component of RANK signaling and osteoclastogenesis.

Q9ES66	CAN10_RAT	Calpain-10	11375982	Characterization and expression of calpain 10. A novel ubiquitous calpain with nuclear localization.

Q9Y672	ALG6_HUMAN	Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase	10924277	Analysis of multiple mutations in the hALG6 gene in a patient with congenital disorder of glycosylation Ic.

P35918	VGFR2_MOUSE	Vascular endothelial growth factor receptor 2	7681362	High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis.

Q92878	RAD50_HUMAN	DNA repair protein RAD50	8756642	Human Rad50 is physically associated with human Mre11: identification of a conserved multiprotein complex implicated in recombinational DNA repair.

Q8TD84	DSCL1_HUMAN	Down syndrome cell adhesion molecule-like protein 1	11453658	Cloning and functional characterization of DSCAML1, a novel DSCAM- like cell adhesion molecule that mediates homophilic intercellular adhesion.

O60603	TLR2_HUMAN	Toll-like receptor 2	10426996	Cell activation and apoptosis by bacterial lipoproteins through Toll- like receptor-2.

P31463	YIDZ_ECOLI	HTH-type transcriptional regulator yidZ	15546870	New genes implicated in the protection of anaerobically grown Escherichia coli against nitric oxide.

P27133	COROA_DICDI	Coronin-A	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q2PPJ7	RGPA2_HUMAN	Ral GTPase-activating protein subunit alpha-2	16490346	Adipocytes contain a novel complex similar to the tuberous sclerosis complex.

Q8K3M6	ERC2_RAT	ERC protein 2	12163476	Cast: a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and Munc13-1.

Q9Y6R0	NUMBL_HUMAN	Numb-like protein	18299187	NUMBL interacts with TAB2 and inhibits TNFalpha and IL-1beta-induced NF-kappaB activation.

Q12233	ATPN_YEAST	ATP synthase subunit g, mitochondrial	9857174	Yeast mitochondrial F1F0-ATPase exists as a dimer: identification of three dimer-specific subunits.

P45880	VDAC2_HUMAN	Voltage-dependent anion-selective channel protein 2	8420959	Cloning and functional expression in yeast of two human isoforms of the outer mitochondrial membrane channel, the voltage-dependent anion channel.

P40388	UVI15_SCHPO	UV-induced protein uvi15	7898433	Characterization of uvi15+, a stress-inducible gene from Schizosaccharomyces pombe.

P31361	PO3F3_MOUSE	POU domain, class 3, transcription factor 3	12130536	Brn-1 and Brn-2 share crucial roles in the production and positioning of mouse neocortical neurons.

P0A9P6	DEAD_ECOLI	Cold-shock DEAD box protein A	15148362	CsdA, a cold-shock RNA helicase from Escherichia coli, is involved in the biogenesis of 50S ribosomal subunit.

O35779	BHE41_RAT	Class E basic helix-loop-helix protein 41	9532582	SHARPs: mammalian enhancer-of-split- and hairy-related proteins coupled to neuronal stimulation.

P19099	C11B2_HUMAN	Cytochrome P450 11B2, mitochondrial	2256920	Cloning and expression of a cDNA for human cytochrome P-450aldo as related to primary aldosteronism.

P42677	RS27_HUMAN	40S ribosomal protein S27	8908372	Primary structures and sequence analysis of human ribosomal proteins L39 and S27.

Q9LFD2	LAC8_ARATH	Laccase-8	16804053	Mutant identification and characterization of the laccase gene family in Arabidopsis.

O94251	YOR1_SCHPO	Uncharacterized protein P8B7.01c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8TBE9	NANP_HUMAN	N-acylneuraminate-9-phosphatase	16237198	Identification of the sequence encoding N-acetylneuraminate-9- phosphate phosphatase.

Q9Y577	TRI17_HUMAN	E3 ubiquitin-protein ligase TRIM17	19358823	TRIM44 interacts with and stabilizes terf, a TRIM ubiquitin E3 ligase.

Q9EST4	PSMG2_MOUSE	Proteasome assembly chaperone 2	12147697	Growth retardation, polyploidy, and multinucleation induced by Clast3, a novel cell cycle-regulated protein.

Q8N726	CD2A2_HUMAN	Cyclin-dependent kinase inhibitor 2A, isoform 4	17110379	A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability.

O60806	TBX19_HUMAN	T-box transcription factor TBX19	9888994	Identification, mapping and phylogenomic analysis of four new human members of the T-box gene family: EOMES, TBX6, TBX18, and TBX19.

P38071	ETR1_YEAST	Enoyl-[acyl-carrier protein] reductase [NADPH, B-specific], mitochondrial	11509667	Candida tropicalis Etr1p and Saccharomyces cerevisiae Ybr026p (Mrf1'p), 2-enoyl thioester reductases essential for mitochondrial respiratory competence.

P38889	SKN7_YEAST	Transcription factor SKN7	10888672	The Skn7 response regulator of Saccharomyces cerevisiae interacts with Hsf1 in vivo and is required for the induction of heat shock genes by oxidative stress.

Q9Y884	SKH1_SCHPO	MAP kinase kinase skh1/pek1	10365961	The MAPK kinase Pek1 acts as a phosphorylation-dependent molecular switch.

P23293	BUR1_YEAST	Serine/threonine-protein kinase BUR1	16040246	BUR kinase selectively regulates H3 K4 trimethylation and H2B ubiquitylation through recruitment of the PAF elongation complex.

P01174	WAP_RAT	Whey acidic protein	6955785	Complete sequence analysis of cDNA clones encoding rat whey phosphoprotein: homology to a protease inhibitor.

P63345	ARC_MYCTU	Proteasome-associated ATPase	17082771	Identification of substrates of the Mycobacterium tuberculosis proteasome.

Q24174	ABRU_DROME	Protein abrupt	15363392	Development of morphological diversity of dendrites in Drosophila by the BTB-zinc finger protein abrupt.

Q9S784	HA22C_ARATH	HVA22-like protein c	12081371	AtHVA22 gene family in Arabidopsis: phylogenetic relationship, ABA and stress regulation, and tissue-specific expression.

P97546	NPTN_RAT	Neuroplastin	19952283	Neuroplastin-55 binds to and signals through the fibroblast growth factor receptor.

O43294	TGFI1_HUMAN	Transforming growth factor beta-1-induced transcript 1 protein	9422762	Cell adhesion kinase beta forms a complex with a new member, Hic-5, of proteins localized at focal adhesions.

P37677	LYXK_ECOLI	L-xylulose/3-keto-L-gulonate kinase	7961955	Activation of a cryptic gene encoding a kinase for L-xylulose opens a new pathway for the utilization of L-lyxose by Escherichia coli.

Q9UUI6	RTF_SCHPO	Replication termination factor 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P01129	CDC10_SCHPO	Start control protein cdc10	16816948	Pol5p, a novel binding partner to Cdc10p in fission yeast involved in rRNA production.

P98073	ENTK_HUMAN	Enteropeptidase	8052624	Enterokinase, the initiator of intestinal digestion, is a mosaic protease composed of a distinctive assortment of domains.

Q92851	CASPA_HUMAN	Caspase-10	11717445	Caspase-10 is an initiator caspase in death receptor signaling.

Q61301	CTNA2_MOUSE	Catenin alpha-2	12123610	Cadherin regulates dendritic spine morphogenesis.

Q673G8	DACT2_DANRE	Dapper homolog 2	15459392	Zebrafish Dpr2 inhibits mesoderm induction by promoting degradation of nodal receptors.

Q06327	LOX1_ARATH	Lipoxygenase 1	18949503	Diversity of the enzymatic activity in the lipoxygenase gene family of Arabidopsis thaliana.

P93022	ARFG_ARATH	Auxin response factor 7	16461383	A role for auxin response factor 19 in auxin and ethylene signaling in Arabidopsis.

P91660	L259_DROME	Probable multidrug resistance-associated protein lethal(2)03659	8985246	The Drosophila protein Wunen repels migrating germ cells.

P53065	TAD1_YEAST	tRNA-specific adenosine deaminase 1	9707437	Tad1p, a yeast tRNA-specific adenosine deaminase, is related to the mammalian pre-mRNA editing enzymes ADAR1 and ADAR2.

P39038	CADH4_MOUSE	Cadherin-4	8270638	Cell binding specificity of mouse R-cadherin and chromosomal mapping of the gene.

P24592	IBP6_HUMAN	Insulin-like growth factor-binding protein 6	10087296	Characterization and chromosomal localization of the human insulin- like growth factor-binding protein 6 gene.

P51843	NR0B1_HUMAN	Nuclear receptor subfamily 0 group B member 1	10848616	Orphan receptor DAX-1 is a shuttling RNA binding protein associated with polyribosomes via mRNA.

Q09022	XEN1_XENLA	Xenoxin-1	8393864	Xenoxins, a family of peptides from dorsal gland secretion of Xenopus laevis related to snake venom cytotoxins and neurotoxins.

Q03395	ROM1_HUMAN	Rod outer segment membrane protein 1	1610568	Cloning of the cDNA for a novel photoreceptor membrane protein (rom- 1) identifies a disk rim protein family implicated in human retinopathies.

Q9VU68	WDR1_DROME	Actin-interacting protein 1	17565945	The flare gene, which encodes the AIP1 protein of Drosophila, functions to regulate F-actin disassembly in pupal epidermal cells.

Q06156	CND1_YEAST	Condensin complex subunit 1	10811823	The condensin complex governs chromosome condensation and mitotic transmission of rDNA.

P20459	IF2A_YEAST	Eukaryotic translation initiation factor 2 subunit alpha	2649894	Yeast translation initiation suppressor sui2 encodes the alpha subunit of eukaryotic initiation factor 2 and shares sequence identity with the human alpha subunit.

P12694	ODBA_HUMAN	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial	7883996	Molecular and biochemical basis of intermediate maple syrup urine disease: occurrence of homozygous G245R and F364C mutations at the E1- alpha locus of Hispanic-Mexican patients.

Q01629	IFM2_HUMAN	Interferon-induced transmembrane protein 2	1906403	Molecular analysis of a human interferon-inducible gene family.

P62746	RHOB_MOUSE	Rho-related GTP-binding protein RhoB	14597666	RhoB controls Akt trafficking and stage-specific survival of endothelial cells during vascular development.

P22579	SIN3_YEAST	Transcriptional regulatory protein SIN3	9234741	A large protein complex containing the yeast Sin3p and Rpd3p transcriptional regulators.

Q7KSD8	TAD2A_DROME	Transcriptional adapter 2A	12482983	Two different Drosophila ADA2 homologues are present in distinct GCN5 histone acetyltransferase-containing complexes.

P05230	FGF1_HUMAN	Heparin-binding growth factor 1	1693186	Alternative splicing generates two forms of mRNA coding for human heparin-binding growth factor 1.

P05408	7B2_HUMAN	Neuroendocrine protein 7B2	3134253	Cloning and sequence analysis of human pituitary cDNA encoding the novel polypeptide 7B2.

P40554	URM1_YEAST	Ubiquitin-related modifier 1	14555475	Attachment of the ubiquitin-related protein Urm1p to the antioxidant protein Ahp1p.

Q9FYG2	CMTA4_ARATH	Calmodulin-binding transcription activator 4	12218065	A calmodulin-binding/CGCG box DNA-binding protein family involved in multiple signaling pathways in plants.

P40077	DSE1_YEAST	Protein DSE1	14562095	Global analysis of protein localization in budding yeast.

Q03771	YD161_YEAST	UPF0661 TPR repeat-containing protein YDR161W	14562095	Global analysis of protein localization in budding yeast.

Q10290	MAL2_SCHPO	Chromosome segregation protein mal2	16079914	Molecular analysis of kinetochore architecture in fission yeast.

Q9T2L1	CB2C_SPIOL	Chlorophyll a-b binding protein	1894641	Tandem mass spectrometry identifies sites of three post-translational modifications of spinach light-harvesting chlorophyll protein II. Proteolytic cleavage, acetylation, and phosphorylation.

Q9UKJ8	ADA21_HUMAN	Disintegrin and metalloproteinase domain-containing protein 21	9469942	ADAM 20 and 21; two novel human testis-specific membrane metalloproteases with similarity to fertilin-alpha.

O60733	PA2G6_HUMAN	85 kDa calcium-independent phospholipase A2	9417066	Multiple splice variants of the human calcium-independent phospholipase A2 and their effect on enzyme activity.

P24004	PEX1_YEAST	Peroxisomal ATPase PEX1	14562095	Global analysis of protein localization in budding yeast.

O74331	RLP1_SCHPO	DNA repair protein rlp1	15336631	Identification and characterization of the rlp1+, the novel Rad51 paralog in the fission yeast Schizosaccharomyces pombe.

P80957	BDEF_TACTR	Big defensin	9165083	cDNA cloning, tissue distribution, and subcellular localization of horseshoe crab big defensin.

P53824	SNZ2_YEAST	Probable pyridoxine biosynthesis protein SNZ2	12271461	Functional analysis of yeast gene families involved in metabolism of vitamins B1 and B6.

Q9ZR07	FRDA_ARATH	Frataxin, mitochondrial	17092311	Deficiency of Arabidopsis thaliana frataxin alters activity of mitochondrial Fe-S proteins and induces oxidative stress.

P26263	PDC6_YEAST	Pyruvate decarboxylase isozyme 3	1744053	Characterization of PDC6, a third structural gene for pyruvate decarboxylase in Saccharomyces cerevisiae.

Q9ZES5	SLAP_BACTF	S-layer protein	12549017	Cloning of parasporal body protein gene resembling to S-layer protein genes from Bacillus thuringiensis CTC strain.

Q25QX6	BOWL_XENLA	Protein bowline	16586348	Bowline, a novel protein localized to the presomitic mesoderm, interacts with Groucho/TLE in Xenopus.

P35189	TAF14_YEAST	Transcription initiation factor TFIID subunit 14	12887900	Involvement of actin-related proteins in ATP-dependent chromatin remodeling.

Q13033	STRN3_HUMAN	Striatin-3	10748158	Zinedin, SG2NA, and striatin are calmodulin-binding, WD repeat proteins principally expressed in the brain.

Q9U6M3	JBP1_TRYBB	Thymine dioxygenase JBP1	15694344	Regulation of trypanosome DNA glycosylation by a SWI2/SNF2-like protein.

O70456	1433S_MOUSE	14-3-3 protein sigma	16710422	A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth.

Q8K450	SPG16_MOUSE	Sperm-associated antigen 16 protein	12391165	A sperm-associated WD repeat protein orthologous to Chlamydomonas PF20 associates with Spag6, the mammalian orthologue of Chlamydomonas PF16.

Q9W420	SPT6H_DROME	Transcription elongation factor SPT6	11040216	Spt5 and spt6 are associated with active transcription and have characteristics of general elongation factors in D. melanogaster.

P09874	PARP1_HUMAN	Poly [ADP-ribose] polymerase 1	2513174	Human nuclear NAD+ ADP-ribosyltransferase(polymerizing): organization of the gene.

P00782	SUBT_BACAM	Subtilisin BPN'	12524032	Purification and characterization of a fibrinolytic enzyme produced by Bacillus amyloliquefaciens DC-4 screened from douchi, a traditional Chinese soybean food.

Q99816	TS101_HUMAN	Tumor susceptibility gene 101 protein	10888872	DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci.

Q02563	SV2A_RAT	Synaptic vesicle glycoprotein 2A	1519064	SV2, a brain synaptic vesicle protein homologous to bacterial transporters.

P41759	PGK_SCHMA	Phosphoglycerate kinase	7477104	Cloning of the gene for phosphoglycerate kinase from Schistosoma mansoni and characterization of its gene product.

Q11193	SOR3_CAEEL	Sop-2-related protein 3	17215367	Polycomb-like genes are necessary for specification of dopaminergic and serotonergic neurons in Caenorhabditis elegans.

Q03388	VPS72_YEAST	Vacuolar protein sorting-associated protein 72	14562095	Global analysis of protein localization in budding yeast.

Q9V727	ASX_DROME	Polycomb protein Asx	11397012	Tantalus, a novel ASX-interacting protein with tissue-specific functions.

O60123	KEX1_SCHPO	Carboxypeptidase kex1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q54J33	P2XD_DICDI	P2X receptor D	19833731	Functional characterization of intracellular Dictyostelium discoideum P2X receptors.

P40994	ARF3_YEAST	ADP-ribosylation factor 3	15504911	The GTPase Arf1p and the ER to Golgi cargo receptor Erv14p cooperate to recruit the golgin Rud3p to the cis-Golgi.

O88667	RAD_MOUSE	GTP-binding protein RAD	17525370	Dominant negative suppression of Rad leads to QT prolongation and causes ventricular arrhythmias via modulation of L-type Ca2+ channels in the heart.

Q84WU4	GOGC3_ARATH	Golgin candidate 3	17307898	Multiple roles of ADP-ribosylation factor 1 in plant cells include spatially regulated recruitment of coatomer and elements of the Golgi matrix.

Q03151	MTG1_YEAST	Mitochondrial GTPase 1	12808030	MTG1 codes for a conserved protein required for mitochondrial translation.

Q03071	ELOC_YEAST	Elongin-C	10753924	Elongin from Saccharomyces cerevisiae.

Q99952	PTN18_HUMAN	Tyrosine-protein phosphatase non-receptor type 18	8950995	Characterization of the PEST family protein tyrosine phosphatase BDP1.

Q8R3H7	HS2ST_MOUSE	Heparan sulfate 2-O-sulfotransferase 1	9637690	Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase.

Q9LRZ0	TPR2_ARATH	Topless-related protein 2	20360743	NINJA connects the co-repressor TOPLESS to jasmonate signalling.

P38182	ATG8_YEAST	Autophagy-related protein 8	10525546	Formation process of autophagosome is traced with Apg8/Aut7p in yeast.

Q9LG26	PARN_ARATH	Poly(A)-specific ribonuclease PARN	16359390	Analysis of ABA hypersensitive germination2 revealed the pivotal functions of PARN in stress response in Arabidopsis.

P63272	SPT4H_HUMAN	Transcription elongation factor SPT4	10075709	Structure and function of the human transcription elongation factor DSIF.

Q08967	FLC1_YEAST	Flavin carrier protein 1	16717099	A screen for genes of heme uptake identifies the FLC family required for import of FAD into the endoplasmic reticulum.

Q9VTI8	CHRB_DROME	Protein charybde	15545626	The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila.

P52877	SERC_SPIOL	Phosphoserine aminotransferase, chloroplastic	9037153	Molecular cloning, characterization and expression of cDNA encoding phosphoserine aminotransferase involved in phosphorylated pathway of serine biosynthesis from spinach.

Q9VZL7	GR63A_DROME	Gustatory and odorant receptor 63a	17167414	Two chemosensory receptors together mediate carbon dioxide detection in Drosophila.

P47169	ECM17_YEAST	Sulfite reductase [NADPH] subunit beta	14562095	Global analysis of protein localization in budding yeast.

O48963	PHOT1_ARATH	Phototropin-1	16777956	PHYTOCHROME KINASE SUBSTRATE 1 is a phototropin 1 binding protein required for phototropism.

P43006	EAA2_MOUSE	Excitatory amino acid transporter 2	7698742	Mouse excitatory amino acid transporter EAAT2: isolation, characterization, and proximity to neuroexcitability loci on mouse chromosome 2.

P47069	MPS3_YEAST	Spindle pole body assembly component MPS3	17495028	MPS3 mediates meiotic bouquet formation in Saccharomyces cerevisiae.

Q9Y2G2	CARD8_HUMAN	Caspase recruitment domain-containing protein 8	15030775	NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder.

Q64591	DECR_RAT	2,4-dienoyl-CoA reductase, mitochondrial	2383590	cDNA cloning of rat liver 2,4-dienoyl-CoA reductase.

B0F0H3	MKRN2_XENLA	Probable E3 ubiquitin-protein ligase makorin-2	18198183	Makorin-2 is a neurogenesis inhibitor downstream of phosphatidylinositol 3-kinase/Akt (PI3K/Akt) signal.

P09651	ROA1_HUMAN	Heterogeneous nuclear ribonucleoprotein A1	8521471	A nuclear export signal in hnRNP A1: a signal-mediated, temperature- dependent nuclear protein export pathway.

P63279	UBC9_HUMAN	SUMO-conjugating enzyme UBC9	12072434	Transcription factor AP-2 interacts with the SUMO-conjugating enzyme UBC9 and is sumolated in vivo.

P04147	PABP_YEAST	Polyadenylate-binding protein, cytoplasmic and nuclear	10357826	The yeast poly(A)-binding protein Pab1p stimulates in vitro poly(A)- dependent and cap-dependent translation by distinct mechanisms.

P28231	CXB3_MOUSE	Gap junction beta-3 protein	19864490	Consortin, a trans-Golgi network cargo receptor for the plasma membrane targeting and recycling of connexins.

P84386	XT6_XENTR	Antimicrobial peptide 6	11738090	Antimicrobial peptides isolated from skin secretions of the diploid frog, Xenopus tropicalis (Pipidae).

P0AG30	RHO_ECOLI	Transcription termination factor Rho	2423505	Autogenous regulation of the gene for transcription termination factor rho in Escherichia coli: localization and function of its attenuators.

Q9TW67	NGLY1_CAEEL	Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	17509531	Dual enzymatic properties of the cytoplasmic peptide: N-glycanase in C. elegans.

O16850	FOXO_CAEEL	Forkhead box protein O	18245330	DAF-16-dependent suppression of immunity during reproduction in Caenorhabditis elegans.

O13904	MUG84_SCHPO	Meiotically up-regulated gene 84 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q92206	ERG1_CANAL	Squalene monooxygenase	9161422	Cloning and expression of squalene epoxidase from the pathogenic yeast Candida albicans.

P39010	AKR1_YEAST	Palmitoyltransferase AKR1	12370247	The yeast DHHC cysteine-rich domain protein Akr1p is a palmitoyl transferase.

P49643	PRI2_HUMAN	DNA primase large subunit	8026492	DNA replication in vitro by recombinant DNA-polymerase-alpha- primase.

Q9QYN8	HRH3_RAT	Histamine H3 receptor	10869375	Cloning of rat histamine H3 receptor reveals distinct species pharmacological profiles.

Q12324	YVC1_YEAST	Calcium channel YVC1	11781332	Internal Ca(2+) release in yeast is triggered by hypertonic shock and mediated by a TRP channel homologue.

O48788	Y2267_ARATH	Probable inactive receptor kinase At2g26730	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

O75360	PROP1_HUMAN	Homeobox protein prophet of Pit-1	9462743	Mutations in PROP1 cause familial combined pituitary hormone deficiency.

O75398	DEAF1_HUMAN	Deformed epidermal autoregulatory factor 1 homolog	9773984	Characterization of a nuclear deformed epidermal autoregulatory factor-1 (DEAF-1)-related (NUDR) transcriptional regulator protein.

Q63644	ROCK1_RAT	Rho-associated protein kinase 1	8816443	The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton.

Q8K3W2	LRC10_MOUSE	Leucine-rich repeat-containing protein 10	14751244	Molecular cloning and expression of HRLRRP, a novel heart-restricted leucine-rich repeat protein.

O57311	ZIC3_XENLA	Zinc finger protein ZIC 3	9342348	Xenopus Zic3, a primary regulator both in neural and neural crest development.

P32234	128UP_DROME	GTP-binding protein 128up	8121394	The gene upstream of DmRP128 codes for a novel GTP-binding protein of Drosophila melanogaster.

Q9UPY3	DICER_HUMAN	Endoribonuclease Dicer	16142218	TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing.

Q9VEA5	RPB4_DROME	DNA-directed RNA polymerase II 16 kDa polypeptide	12697829	Two Drosophila Ada2 homologues function in different multiprotein complexes.

Q9UMF0	ICAM5_HUMAN	Intercellular adhesion molecule 5	8995416	cDNA cloning and chromosomal localization of the human telencephalin and its distinctive interaction with lymphocyte function-associated antigen-1.

Q03060	CREM_HUMAN	cAMP-responsive element modulator	8206879	Novel isoforms of human cyclic AMP-responsive element modulator (hCREM) mRNA.

P38876	PTH_YEAST	Peptidyl-tRNA hydrolase	12799450	Peptidyl-tRNA hydrolase from Sulfolobus solfataricus.

Q04411	URC2_YEAST	Uracil catabolism protein 2	14562095	Global analysis of protein localization in budding yeast.

O94818	NOL4_HUMAN	Nucleolar protein 4	9813152	NOLP: identification of a novel human nucleolar protein and determination of sequence requirements for its nucleolar localization.

Q50H32	GRCR1_MOUSE	Glutaredoxin domain-containing cysteine-rich protein 1	11276175	Hair cells in the inner ear of the pirouette and shaker 2 mutant mice.

Q02040	SF17A_HUMAN	Splicing factor, arginine/serine-rich 17A	1438229	Cloning and sequencing of a trophoblast-endothelial-activated lymphocyte surface protein: cDNA sequence and genomic structure.

Q9D0J4	ARL2_MOUSE	ADP-ribosylation factor-like protein 2	11980706	The complex of Arl2-GTP and PDE delta: from structure to function.

Q54HL6	CSN2_DICDI	COP9 signalosome complex subunit 2	16781008	The COP9 signalosome regulates cell proliferation of Dictyostelium discoideum.

Q9Y048	DTN1_CAEEL	Dystrobrevin-1	14499607	The stn-1 syntrophin gene of C.elegans is functionally related to dystrophin and dystrobrevin.

O95810	SDPR_HUMAN	Serum deprivation-response protein	10191091	The human serum deprivation response gene (SDPR) maps to 2q32-q33 and codes for a phosphatidylserine-binding protein.

P37765	RLUB_ECOLI	Ribosomal large subunit pseudouridine synthase B	11720289	Identification and site of action of the remaining four putative pseudouridine synthases in Escherichia coli.

Q9USR2	UBP10_SCHPO	Probable mRNA-splicing protein ubp10	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P30430	FUR1C_DROME	Furin-like protease 1, isoform 1-CRR	1545235	A unique Kex2-like endoprotease from Drosophila melanogaster is expressed in the central nervous system during early embryogenesis.

P84638	CYVB_LEOCM	Cycloviolin-B	10813905	Cycloviolins A-D, anti-HIV macrocyclic peptides from Leonia cymosa.

O60667	FAIM3_HUMAN	Fas apoptotic inhibitory molecule 3	9586636	Toso, a cell surface, specific regulator of Fas-induced apoptosis in T cells.

P31270	HXA11_HUMAN	Homeobox protein Hox-A11	9745033	Evolutionary conservation and tissue-specific processing of hoxa 11 antisense transcripts.

Q22830	OSM1_CAEEL	Intraflagellar transport protein osm-1	10545497	Role of a class DHC1b dynein in retrograde transport of IFT motors and IFT raft particles along cilia, but not dendrites, in chemosensory neurons of living Caenorhabditis elegans.

O74757	HRD1_SCHPO	ERAD-associated E3 ubiquitin-protein ligase hrd1	19520858	Degradation of sterol regulatory element-binding protein precursor requires the endoplasmic reticulum-associated degradation components Ubc7 and Hrd1 in fission yeast.

P47175	HMS2_YEAST	Probable transcription factor HMS2	14562095	Global analysis of protein localization in budding yeast.

Q9BY76	ANGL4_HUMAN	Angiopoietin-related protein 4	11953136	Cloning of a novel gene, ANGPTL4 and the functional study in angiogenesis.

Q8K4Z6	GPC6A_MOUSE	G-protein coupled receptor family C group 6 member A	16199532	Identification of a novel extracellular cation-sensing G-protein- coupled receptor.

P50440	GATM_HUMAN	Glycine amidinotransferase, mitochondrial	9218780	Crystal structure and mechanism of human L-arginine:glycine amidinotransferase: a mitochondrial enzyme involved in creatine biosynthesis.

Q98TW1	NCOA2_DANRE	Nuclear receptor coactivator 2	18248177	Cloning, genomic organization, and expression analysis of zebrafish nuclear receptor coactivator, TIF2.

Q8CJ70	IL19_MOUSE	Interleukin-19	12370360	IL-19 induces production of IL-6 and TNF-alpha and results in cell apoptosis through TNF-alpha.

Q8IN81	FRU_DROME	Sex determination protein fruitless	10934470	Formation of the male-specific muscle in female Drosophila by ectopic fruitless expression.

P80723	BASP1_HUMAN	Brain acid soluble protein 1	9749536	Characterization of bovine and human cDNAs encoding NAP-22 (22 kDa neuronal tissue-enriched acidic protein) homologs.

Q96D96	HVCN1_HUMAN	Voltage-gated hydrogen channel 1	16554753	A voltage-gated proton-selective channel lacking the pore domain.

Q8NEJ0	DUS18_HUMAN	Dual specificity protein phosphatase 18	12408986	Identification and characterization of two novel low-molecular-weight dual specificity phosphatases.

P14713	PHYB_ARATH	Phytochrome B	11260718	An Arabidopsis circadian clock component interacts with both CRY1 and phyB.

O74824	GTR1_SCHPO	GTP-binding protein gtr1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O94318	VPS20_SCHPO	Vacuolar protein sorting-associated protein 20	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P07270	PHO4_YEAST	Phosphate system positive regulatory protein PHO4	10320381	Roles of phosphorylation sites in regulating activity of the transcription factor Pho4.

O94236	EIF3D_SCHPO	Eukaryotic translation initiation factor 3 subunit D	11705997	Moe1 and spInt6, the fission yeast homologues of mammalian translation initiation factor 3 subunits p66 (eIF3d) and p48 (eIF3e), respectively, are required for stable association of eIF3 subunits.

O13889	E2AK1_SCHPO	Eukaryotic translation initiation factor 2-alpha kinase 1	12242291	Phosphorylation of eukaryotic initiation factor 2 by heme-regulated inhibitor kinase-related protein kinases in Schizosaccharomyces pombe is important for resistance to environmental stresses.

O00472	ELL2_HUMAN	RNA polymerase II elongation factor ELL2	9108030	ELL2, a new member of an ELL family of RNA polymerase II elongation factors.

P22133	MDHC_YEAST	Malate dehydrogenase, cytoplasmic	1986231	Isolation, nucleotide sequence analysis, and disruption of the MDH2 gene from Saccharomyces cerevisiae: evidence for three isozymes of yeast malate dehydrogenase.

P12729	PSA_DICDI	Prespore-specific protein A	2850494	Structural characterization of Dictyostelium discoideum prespore- specific gene D19 and of its product, cell surface glycoprotein PsA.

P51140	DSH_DROME	Segment polarity protein dishevelled	16849595	An unconventional nuclear localization motif is crucial for function of the Drosophila Wnt/wingless antagonist Naked cuticle.

P36894	BMR1A_HUMAN	Bone morphogenetic protein receptor type-1A	8397373	Activin receptor-like kinases: a novel subclass of cell-surface receptors with predicted serine/threonine kinase activity.

Q9LPW7	AFB3_ARATH	Protein AUXIN SIGNALING F-BOX 3	16627744	A plant miRNA contributes to antibacterial resistance by repressing auxin signaling.

P16092	FGFR1_MOUSE	Basic fibroblast growth factor receptor 1	17086194	Klotho converts canonical FGF receptor into a specific receptor for FGF23.

Q9FUY2	LEUNG_ARATH	Transcriptional corepressor LEUNIG	16679456	AGL24, SHORT VEGETATIVE PHASE, and APETALA1 redundantly control AGAMOUS during early stages of flower development in Arabidopsis.

Q94F47	UBC28_ARATH	Ubiquitin-conjugating enzyme E2 28	16339806	Genome analysis and functional characterization of the E2 and RING- type E3 ligase ubiquitination enzymes of Arabidopsis.

P30664	MCM4B_XENLA	DNA replication licensing factor mcm4-B	16369567	The ATPase activity of MCM2-7 is dispensable for pre-RC assembly but is required for DNA unwinding.

Q13572	ITPK1_HUMAN	Inositol-tetrakisphosphate 1-kinase	8662638	Isolation of inositol 1,3,4-trisphosphate 5/6-kinase, cDNA cloning and expression of the recombinant enzyme.

Q8NF91	SYNE1_HUMAN	Nesprin-1	18396275	Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness.

Q08826	SNX3_YEAST	Sorting nexin-3	9456318	Retrieval of resident late-Golgi membrane proteins from the prevacuolar compartment of Saccharomyces cerevisiae is dependent on the function of Grd19p.

P34697	SODC_CAEEL	Superoxide dismutase [Cu-Zn]	16234242	Activation of CuZn superoxide dismutases from Caenorhabditis elegans does not require the copper chaperone CCS.

P53088	CTU1_YEAST	Cytoplasmic tRNA 2-thiolation protein 1	14551258	Urmylation: a ubiquitin-like pathway that functions during invasive growth and budding in yeast.

P84383	XT3_XENTR	Antimicrobial peptide 3	11738090	Antimicrobial peptides isolated from skin secretions of the diploid frog, Xenopus tropicalis (Pipidae).

Q63517	CENPI_RAT	Centromere protein I	7758824	Regulation of gene expression in Sertoli cells by follicle- stimulating hormone (FSH): cloning and characterization of LRPR1, a primary response gene encoding a leucine-rich protein.

Q9UT54	YI95_SCHPO	UPF0593 mitochondrial protein C806.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P23258	TBG1_HUMAN	Tubulin gamma-1 chain	1904010	Gamma-tubulin is present in Drosophila melanogaster and Homo sapiens and is associated with the centrosome.

Q9LKW9	NHX7_ARATH	Sodium/hydrogen exchanger 7	12239394	SOS1, a genetic locus essential for salt tolerance and potassium acquisition.

P12866	STE6_YEAST	Alpha-factor-transporting ATPase	2569166	The yeast STE6 gene encodes a homologue of the mammalian multidrug resistance P-glycoprotein.

Q1PEF6	ASK6_ARATH	SKP1-like protein 6	12970487	Members of the Arabidopsis-SKP1-like gene family exhibit a variety of expression patterns and may play diverse roles in Arabidopsis.

P35169	TOR1_YEAST	Serine/threonine-protein kinase TOR1	12631735	Tor kinases are in distinct membrane-associated protein complexes in Saccharomyces cerevisiae.

P17947	SPI1_HUMAN	Transcription factor PU.1	10207087	Functional and physical interactions between AML1 proteins and an ETS protein, MEF: implications for the pathogenesis of t(8;21)-positive leukemias.

P24889	NU2M_CAEEL	NADH-ubiquinone oxidoreductase chain 2	1551572	The mitochondrial genomes of two nematodes, Caenorhabditis elegans and Ascaris suum.

Q9LMA8	TI10A_ARATH	Protein TIFY 10A	17637677	JAZ repressor proteins are targets of the SCF(COI1) complex during jasmonate signalling.

Q9Z2C8	YBOX2_MOUSE	Y-box-binding protein 2	12648488	Requirement for RNA-binding activity of MSY2 for cytoplasmic localization and retention in mouse oocytes.

Q3E8E5	BGL39_ARATH	Putative myrosinase 3	12010464	The third myrosinase gene TGG3 in Arabidopsis thaliana is a pseudogene specifically expressed in stamen and petal.

P70041	CER1_XENLA	Cerberus	10067895	The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals.

P63092	GNAS2_HUMAN	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	9159128	Conditional activation defect of a human Gsalpha mutant.

P25039	EFGM_YEAST	Elongation factor G, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P20594	ANPRB_HUMAN	Atrial natriuretic peptide receptor 2	1660465	Extracellular domain-IgG fusion proteins for three human natriuretic peptide receptors. Hormone pharmacology and application to solid phase screening of synthetic peptide antisera.

Q9H9Y2	RPF1_HUMAN	Ribosome production factor 1	11864606	The sigma(70)-like motif: a eukaryotic RNA binding domain unique to a superfamily of proteins required for ribosome biogenesis.

Q9M4A2	SPO11_ARATH	Meiotic recombination protein SPO11-1	11157765	AtSPO11-1 is necessary for efficient meiotic recombination in plants.

P42701	I12R1_HUMAN	Interleukin-12 receptor subunit beta-1	8943050	A functional interleukin 12 receptor complex is composed of two beta- type cytokine receptor subunits.

P31268	HXA7_HUMAN	Homeobox protein Hox-A7	11435435	Human homeobox HOXA7 regulates keratinocyte transglutaminase type 1 and inhibits differentiation.

Q9SJ12	ATP7_ARATH	Probable ATP synthase 24 kDa subunit, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

O45657	PLX2_CAEEL	Plexin-2	15030761	Integration of semaphorin-2A/MAB-20, ephrin-4, and UNC-129 TGF-beta signaling pathways regulates sorting of distinct sensory rays in C. elegans.

Q07980	MLH2_YEAST	DNA mismatch repair protein MLH2	15467363	A role for the MutL homologue MLH2 in controlling heteroduplex formation and in regulating between two different crossover pathways in budding yeast.

O00755	WNT7A_HUMAN	Protein Wnt-7a	8893824	Isolation, characterization and chromosomal assignment of the human WNT7A gene.

P42523	TGRC1_DICDI	Tiger protein C1	14651934	A cell-adhesion pathway regulates intercellular communication during Dictyostelium development.

P35414	APJ_HUMAN	Apelin receptor	8294032	A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11.

Q9Y215	COLQ_HUMAN	Acetylcholinesterase collagenic tail peptide	9689136	Human endplate acetylcholinesterase deficiency caused by mutations in the collagen-like tail subunit (ColQ) of the asymmetric enzyme.

O46107	LIP1_DROME	Lipase 1	9566193	The Drosophila melanogaster lipase homologs: a gene family with tissue and developmental specific expression.

Q93561	DERL1_CAEEL	Derlin-1	11560892	Genetic analysis of endocytosis in Caenorhabditis elegans: coelomocyte uptake defective mutants.

Q16560	U1SBP_HUMAN	U11/U12 small nuclear ribonucleoprotein 35 kDa protein	15146077	The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome.

P42939	MVB12_YEAST	Multivesicular body sorting factor 12	17135292	Efficient cargo sorting by ESCRT-I and the subsequent release of ESCRT-I from multivesicular bodies requires the subunit Mvb12.

O14216	SLD2_SCHPO	DNA replication regulator sld2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q3KQ35	S17AA_XENLA	Transcription factor Sox-17-alpha-A	10549281	Regulation of Wnt signaling by Sox proteins: XSox17 alpha/beta and XSox3 physically interact with beta-catenin.

Q7TSY8	SGOL2_MOUSE	Shugoshin-like 2	18084284	Unified mode of centromeric protection by shugoshin in mammalian oocytes and somatic cells.

P10911	MCF2_HUMAN	Proto-oncogene DBL	3281159	The predicted DBL oncogene product defines a distinct class of transforming proteins.

Q9Y2T1	AXN2_HUMAN	Axin-2	15042511	Mutations in AXIN2 cause familial tooth agenesis and predispose to colorectal cancer.

O94319	SEC13_SCHPO	Protein transport protein sec13	11821054	A DMSO-sensitive conditional mutant of the fission yeast orthologue of the Saccharomyces cerevisiae SEC13 gene is defective in septation.

Q99542	MMP19_HUMAN	Matrix metalloproteinase-19	10809722	Biochemical characterization of the catalytic domain of human matrix metalloproteinase 19. Evidence for a role as a potent basement membrane degrading enzyme.

Q03957	CTK1_YEAST	CTD kinase subunit alpha	15520468	CTD kinase I is involved in RNA polymerase I transcription.

Q38998	AKT1_ARATH	Potassium channel AKT1	16895985	A Ca(2)+ signaling pathway regulates a K(+) channel for low-K response in Arabidopsis.

O74700	TIM9_YEAST	Mitochondrial import inner membrane translocase subunit TIM9	12138093	Assembly of Tim9 and Tim10 into a functional chaperone.

O43019	SRE2_SCHPO	Putative transcription factor sre2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P34446	PAT2_CAEEL	Integrin alpha pat-2	17606640	Control of C. elegans hermaphrodite gonad size and shape by vab- 3/Pax6-mediated regulation of integrin receptors.

P27815	PDE4A_HUMAN	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	11306681	Molecular cloning, genomic positioning, promoter identification, and characterization of the novel cyclic AMP-specific phosphodiesterase PDE4A10.

P35177	SPT7_YEAST	Transcriptional activator SPT7	7713415	The Saccharomyces cerevisiae SPT7 gene encodes a very acidic protein important for transcription in vivo.

O43028	VAC8_SCHPO	Vacuolar protein 8	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P51888	PRELP_HUMAN	Prolargin	7592739	The primary structure of a basic leucine-rich repeat protein, PRELP, found in connective tissues.

Q9ES07	S15A2_MOUSE	Solute carrier family 15 member 2	11027540	Cloning and characterization of the gene encoding the mouse peptide transporter PEPT2.

P06101	CDC37_YEAST	Hsp90 co-chaperone Cdc37	7753858	Cdc37 is required for association of the protein kinase Cdc28 with G1 and mitotic cyclins.

Q9P7Z9	YCGK_SCHPO	Uncharacterized protein C16C4.20c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q63191	AEGP_RAT	Apical endosomal glycoprotein	7829488	Molecular characterization of an apical early endosomal glycoprotein from developing rat intestinal epithelial cells.

Q9WTL3	SEM6C_RAT	Semaphorin-6C	10049528	Cloning and characterization of a novel class VI semaphorin, semaphorin Y.

Q06091	SN309_YEAST	Pre-mRNA-splicing factor SNT309	9528791	Snt309p, a component of the Prp19p-associated complex that interacts with Prp19p and associates with the spliceosome simultaneously with or immediately after dissociation of U4 in the same manner as Prp19p.

Q9C9L0	CUL3B_ARATH	Cullin-3B	16045478	Arabidopsis CUL3A and CUL3B genes are essential for normal embryogenesis.

P01571	IFN17_HUMAN	Interferon alpha-17	3891272	Efficient expression in Escherichia coli of two species of human interferon-alpha and their hybrid molecules.

Q9WVC3	CAV2_MOUSE	Caveolin-2	10373486	The membrane-spanning domains of caveolins-1 and -2 mediate the formation of caveolin hetero-oligomers. Implications for the assembly of caveolae membranes in vivo.

Q9ZT63	MTP1_ARATH	Metal tolerance protein 1	15215502	Isolation of intact vacuoles and proteomic analysis of tonoplast from suspension-cultured cells of Arabidopsis thaliana.

Q9H1J5	WNT8A_HUMAN	Protein Wnt-8a	11408932	Molecular cloning and characterization of human WNT8A.

Q26366	VG_DROME	Protein vestigial	14526388	The Drosophila wing differentiation factor vestigial-scalloped is required for cell proliferation and cell survival at the dorso-ventral boundary of the wing imaginal disc.

O49686	PYR1_ARATH	Abscisic acid receptor PYR1	19874541	PYR/PYL/RCAR family members are major in-vivo ABI1 protein phosphatase 2C-interacting proteins in Arabidopsis.

P92199	ROCK_CAEEL	Rho-associated protein kinase let-502	11687661	A RHO GTPase-mediated pathway is required during P cell migration in Caenorhabditis elegans.

C4NZN9	HYAST_HYAAR	Hyastatin	19487032	Hyastatin, a glycine-rich multi-domain antimicrobial peptide isolated from the spider crab (Hyas araneus) hemocytes.

Q15722	LT4R1_HUMAN	Leukotriene B4 receptor 1	8702478	Molecular cloning of a novel P2 purinoceptor from human erythroleukemia cells.

Q55DM1	LVSA_DICDI	BEACH domain-containing protein lvsA	10588668	LvsA, a protein related to the mouse beige protein, is required for cytokinesis in Dictyostelium.

Q90ZH9	S17AB_XENLA	Transcription factor Sox-17-alpha-B	16651540	Global analysis of the transcriptional network controlling Xenopus endoderm formation.

Q96M11	HYLS1_HUMAN	Hydrolethalus syndrome protein 1	15843405	Hydrolethalus syndrome is caused by a missense mutation in a novel gene HYLS1.

P32769	HBS1_YEAST	Elongation factor 1 alpha-like protein	16554824	Endonucleolytic cleavage of eukaryotic mRNAs with stalls in translation elongation.

P80313	TCPH_MOUSE	T-complex protein 1 subunit eta	7953530	Identification of six Tcp-1-related genes encoding divergent subunits of the TCP-1-containing chaperonin.

P06775	HIP1_YEAST	Histidine permease	3905514	The histidine permease gene (HIP1) of Saccharomyces cerevisiae.

P17036	ZNF3_HUMAN	Zinc finger protein 3	2288909	Multiple genes encoding zinc finger domains are expressed in human T cells.

Q15758	AAAT_HUMAN	Neutral amino acid transporter B(0)	8702519	Cloning of the sodium-dependent, broad-scope, neutral amino acid transporter Bo from a human placental choriocarcinoma cell line.

Q8X229	FCR3_CANAL	Fluconazole resistance protein 3	11561289	Functional isolation of the Candida albicans FCR3 gene encoding a bZip transcription factor homologous to Saccharomyces cerevisiae Yap3p.

P05164	PERM_HUMAN	Myeloperoxidase	8621627	Effect of the R569W missense mutation on the biosynthesis of myeloperoxidase.

Q05062	CDC42_CAEEL	Cell division control protein 42 homolog	8514766	The CDC42 homologue from Caenorhabditis elegans. Complementation of yeast mutation.

Q80WF4	T132A_RAT	Transmembrane protein 132A	12514190	Cloning and characterization of a novel GRP78-binding protein in the rat brain.

Q09140	UGGG_SCHPO	UDP-glucose:glycoprotein glucosyltransferase	8631292	A new stress protein: synthesis of Schizosaccharomyces pombe UDP-- Glc:glycoprotein glucosyltransferase mRNA is induced by stress conditions but the enzyme is not essential for cell viability.

Q9CQJ4	RING2_MOUSE	E3 ubiquitin-protein ligase RING2	15525528	Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation.

A0JNT9	BICR1_MOUSE	Bicaudal D-related protein 1	20360680	Pericentrosomal targeting of Rab6 secretory vesicles by Bicaudal-D- related protein 1 (BICDR-1) regulates neuritogenesis.

Q12874	SF3A3_HUMAN	Splicing factor 3A subunit 3	8022796	Specific protein-protein interactions between the essential mammalian spliceosome-associated proteins SAP 61 and SAP 114.

O94353	YHO4_SCHPO	Uncharacterized membrane protein C428.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O14910	LIN7A_HUMAN	Protein lin-7 homolog A	9753324	A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain.

P75864	RLML_ECOLI	Ribosomal RNA large subunit methyltransferase L	17010378	Identification of Escherichia coli m2G methyltransferases: I. the ycbY gene encodes a methyltransferase specific for G2445 of the 23 S rRNA.

P12843	IBP2_RAT	Insulin-like growth factor-binding protein 2	2974285	Isolation of a biologically active fragment from the carboxy terminus of the fetal rat binding protein for insulin-like growth factors.

Q02199	NUP49_YEAST	Nucleoporin NUP49/NSP49	9971735	A novel in vivo assay reveals inhibition of ribosomal nuclear export in ran-cycle and nucleoporin mutants.

Q9V853	SMUF1_DROME	E3 ubiquitin-protein ligase Smurf1	12754252	DSmurf selectively degrades decapentaplegic-activated MAD, and its overexpression disrupts imaginal disc development.

P36012	CENPA_YEAST	Histone H3-like centromeric protein CSE4	16966420	The centromere-specific histone variant Cse4p (CENP-A) is essential for functional chromatin architecture at the yeast 2-micrometer circle partitioning locus and promotes equal plasmid segregation.

Q8VHN7	GPR98_MOUSE	G-protein coupled receptor 98	11606593	Very large G protein-coupled receptor-1, the largest known cell surface protein, is highly expressed in the developing central nervous system.

Q10981	FUT2_HUMAN	Galactoside 2-alpha-L-fucosyltransferase 2	7876235	Sequence and expression of a candidate for the human Secretor blood group alpha(1,2)fucosyltransferase gene (FUT2). Homozygosity for an enzyme-inactivating nonsense mutation commonly correlates with the non-secretor phenotype.

Q16581	C3AR_HUMAN	C3a anaphylatoxin chemotactic receptor	8765043	Expression cloning of the human C3a anaphylatoxin receptor (C3aR) from differentiated U-937 cells.

O14003	RFC3_SCHPO	Replication factor C subunit 3	10588638	Replication factor C3 of Schizosaccharomyces pombe, a small subunit of replication factor C complex, plays a role in both replication and damage checkpoints.

Q96J02	ITCH_HUMAN	E3 ubiquitin-protein ligase Itchy homolog	19881509	PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4.

Q8NFU7	TET1_HUMAN	Methylcytosine dioxygenase TET1	19372391	Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by the MLL fusion partner TET1.

Q9LSY0	ASK7_ARATH	SKP1-like protein 7	12970487	Members of the Arabidopsis-SKP1-like gene family exhibit a variety of expression patterns and may play diverse roles in Arabidopsis.

O60220	TIM8A_HUMAN	Mitochondrial import inner membrane translocase subunit Tim8 A	8841189	A novel X-linked gene, DDP, shows mutations in families with deafness (DFN-1), dystonia, mental deficiency and blindness.

P00520	ABL1_MOUSE	Tyrosine-protein kinase ABL1	9109492	Functional interaction between DNA-PK and c-Abl in response to DNA damage.

Q9UM82	SPAT2_HUMAN	Spermatogenesis-associated protein 2	10222154	cDNA cloning and characterization of PD1: a novel human testicular protein with different expressions in various testiculopathies.

O94528	CAF5_SCHPO	Caffeine resistance protein 5	14758541	The transcription factor Pap1/Caf3 plays a central role in the determination of caffeine resistance in Schizosaccharomyces pombe.

Q71WH7	CBIO2_LISMF	Cobalt import ATP-binding protein CbiO 2	15115801	Whole genome comparisons of serotype 4b and 1/2a strains of the food- borne pathogen Listeria monocytogenes reveal new insights into the core genome components of this species.

Q9D6K9	LASS5_MOUSE	LAG1 longevity assurance homolog 5	12912983	Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors.

Q14746	COG2_HUMAN	Conserved oligomeric Golgi complex subunit 2	7962052	LDLC encodes a brefeldin A-sensitive, peripheral Golgi protein required for normal Golgi function.

P57073	SOX8_HUMAN	Transcription factor SOX-8	10662550	The SOX8 gene is located within 700 kb of the tip of chromosome 16p and is deleted in a patient with ATR-16 syndrome.

P47160	ENT3_YEAST	Epsin-3	12483220	Yeast epsin-related proteins required for Golgi-endosome traffic define a gamma-adaptin ear-binding motif.

Q9ZT50	RHA2A_ARATH	E3 ubiquitin-protein ligase RHA2A	12646039	Interactions between plant RING-H2 and plant-specific NAC (NAM/ATAF1/2/CUC2) proteins: RING-H2 molecular specificity and cellular localization.

P25774	CATS_HUMAN	Cathepsin S	1373132	Molecular cloning and expression of human alveolar macrophage cathepsin S, an elastinolytic cysteine protease.

Q16665	HIF1A_HUMAN	Hypoxia-inducible factor 1-alpha	7539918	Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.

P38313	AME1_YEAST	Central kinetochore subunit AME1	14633972	Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes.

P40558	CFD1_YEAST	Cytosolic Fe-S cluster assembly factor CFD1	17401378	The Cfd1-Nbp35 complex acts as a scaffold for iron-sulfur protein assembly in the yeast cytosol.

O00591	GBRP_HUMAN	Gamma-aminobutyric acid receptor subunit pi	9182563	A novel class of GABAA receptor subunit in tissues of the reproductive system.

P53301	CRH1_YEAST	Probable glycosidase CRH1	15781460	Comprehensive proteomic analysis of Saccharomyces cerevisiae cell walls: identification of proteins covalently attached via glycosylphosphatidylinositol remnants or mild alkali-sensitive linkages.

P52020	ERG1_RAT	Squalene monooxygenase	7814369	Molecular cloning and expression of rat squalene epoxidase.

Q9LPS1	HXK3_ARATH	Hexokinase-3	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q9UBX5	FBLN5_HUMAN	Fibulin-5	10428823	DANCE, a novel secreted RGD protein expressed in developing, atherosclerotic, and balloon-injured arteries.

P09061	ODBB_PSEPU	2-oxoisovalerate dehydrogenase subunit beta	10426958	Crystal structure of 2-oxoisovalerate and dehydrogenase and the architecture of 2-oxo acid dehydrogenase multienzyme complexes.

Q9FRK5	Y1514_ARATH	Uncharacterized membrane protein At1g75140	16618929	Mapping the Arabidopsis organelle proteome.

Q63881	KCND2_RAT	Potassium voltage-gated channel subfamily D member 2	15356203	KChIPs and Kv4 alpha subunits as integral components of A-type potassium channels in mammalian brain.

Q03206	RAC1_CAEEL	Ras-related protein ced-10	8824291	The Caenorhabditis elegans p21-activated kinase (CePAK) colocalizes with CeRac1 and CDC42Ce at hypodermal cell boundaries during embryo elongation.

Q969H0	FBXW7_HUMAN	F-box/WD repeat-containing protein 7	15103331	Phosphorylation-dependent degradation of c-Myc is mediated by the F- box protein Fbw7.

P23566	UBC2_SCHPO	Ubiquitin-conjugating enzyme E2 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q10487	MFS1_SCHPO	Transporter mfs1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O94600	TTI1_SCHPO	TEL2-interacting protein 1	18076573	Rapamycin sensitivity of the Schizosaccharomyces pombe tor2 mutant and organization of two highly phosphorylated TOR complexes by specific and common subunits.

P36024	SIS2_YEAST	Protein SIS2	7705654	Overexpression of SIS2, which contains an extremely acidic region, increases the expression of SWI4, CLN1 and CLN2 in sit4 mutants.

Q8H1Z0	WAX2_ARATH	Protein WAX2	14756310	A novel male-sterile mutant of Arabidopsis thaliana, faceless pollen- 1, produces pollen with a smooth surface and an acetolysis-sensitive exine.

P83189	PS2_PSEPD	Pseudin-2	11689009	Pseudin-2: an antimicrobial peptide with low hemolytic activity from the skin of the paradoxical frog.

Q06697	CDC73_YEAST	Cell division control protein 73	9032243	Cdc73p and Paf1p are found in a novel RNA polymerase II-containing complex distinct from the Srbp-containing holoenzyme.

Q92841	DDX17_HUMAN	Probable ATP-dependent RNA helicase DDX17	8871553	p72: a human nuclear DEAD box protein highly related to p68.

P49711	CTCF_HUMAN	Transcriptional repressor CTCF	9591631	A widely expressed transcription factor with multiple DNA sequence specificity, CTCF, is localized at chromosome segment 16q22.1 within one of the smallest regions of overlap for common deletions in breast and prostate cancers.

P19022	CADH2_HUMAN	Cadherin-2	2384753	N-cadherin gene maps to human chromosome 18 and is not linked to the E-cadherin gene.

A8JR14	APLF_DROME	Aprataxin and PNK-like factor	17396150	A novel human AP endonuclease with conserved zinc-finger-like motifs involved in DNA strand break responses.

P45376	ALDR_MOUSE	Aldose reductase	7851421	Presence of a closely related subgroup in the aldo-ketoreductase family of the mouse.

P62839	UB2D2_RAT	Ubiquitin-conjugating enzyme E2 D2	18359941	Members of the E2D (UbcH5) family mediate the ubiquitination of the conserved cysteine of Pex5p, the peroxisomal import receptor.

P60228	EIF3E_HUMAN	Eukaryotic translation initiation factor 3 subunit E	17322308	Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry.

Q6SJ96	TBPL2_HUMAN	TATA box-binding protein-like protein 2	14634207	TRF3, a TATA-box-binding protein-related factor, is vertebrate- specific and widely expressed.

P33416	HSP78_YEAST	Heat shock protein 78, mitochondrial	8413229	HSP78 encodes a yeast mitochondrial heat shock protein in the Clp family of ATP-dependent proteases.

P33533	OPRD_RAT	Delta-type opioid receptor	7519274	Molecular cloning and expression of a delta-opioid receptor from rat brain.

Q64305	PTF1A_RAT	Pancreas transcription factor 1 subunit alpha	8861960	The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein.

Q8IVI9	NOSTN_HUMAN	Nostrin	12446846	NOSTRIN: a protein modulating nitric oxide release and subcellular distribution of endothelial nitric oxide synthase.

Q54YU6	CRTF_DICDI	CAR1 transcription factor	11493573	CRTF is a novel transcription factor that regulates multiple stages of Dictyostelium development.

Q04609	FOLH1_HUMAN	Glutamate carboxypeptidase 2	8417812	Molecular cloning of a complementary DNA encoding a prostate-specific membrane antigen.

Q05787	HRD3_YEAST	ERAD-associated E3 ubiquitin-protein ligase component HRD3	16619026	The Hrd1p ligase complex forms a linchpin between ER-lumenal substrate selection and Cdc48p recruitment.

P93002	NPR1_ARATH	Regulatory protein NPR1	9019406	The Arabidopsis NPR1 gene that controls systemic acquired resistance encodes a novel protein containing ankyrin repeats.

P08539	GPA1_YEAST	Guanine nucleotide-binding protein alpha-1 subunit	12556475	Effect of the pheromone-responsive G(alpha) and phosphatase proteins of Saccharomyces cerevisiae on the subcellular localization of the Fus3 mitogen-activated protein kinase.

Q16082	HSPB2_HUMAN	Heat shock protein beta-2	9490724	MKBP, a novel member of the small heat shock protein family, binds and activates the myotonic dystrophy protein kinase.

P38760	MIP6_YEAST	RNA-binding protein MIP6	9214641	Mex67p, a novel factor for nuclear mRNA export, binds to both poly(A)+ RNA and nuclear pores.

Q9C9Q8	PMTT_ARATH	Probable pectin methyltransferase QUA2	17461780	The TUMOROUS SHOOT DEVELOPMENT2 gene of Arabidopsis encoding a putative methyltransferase is required for cell adhesion and co- ordinated plant development.

Q16589	CCNG2_HUMAN	Cyclin-G2	8626390	Cyclin G1 and cyclin G2 comprise a new family of cyclins with contrasting tissue-specific and cell cycle-regulated expression.

Q9GNK5	PGPLC_DROME	Peptidoglycan-recognition protein LC	11872802	Requirement for a peptidoglycan recognition protein (PGRP) in Relish activation and antibacterial immune responses in Drosophila.

Q9UNP4	SIAT9_HUMAN	Lactosylceramide alpha-2,3-sialyltransferase	9822625	Expression cloning and functional characterization of human cDNA for ganglioside GM3 synthase.

Q6P179	ERAP2_HUMAN	Endoplasmic reticulum aminopeptidase 2	15691326	Regulation of the human leukocyte-derived arginine aminopeptidase/endoplasmic reticulum-aminopeptidase 2 gene by interferon-gamma.

P38920	MLH1_YEAST	DNA mismatch repair protein MLH1	14562095	Global analysis of protein localization in budding yeast.

Q9UGJ0	AAKG2_HUMAN	5'-AMP-activated protein kinase subunit gamma-2	15877279	Fatal congenital heart glycogenosis caused by a recurrent activating R531Q mutation in the gamma 2-subunit of AMP-activated protein kinase (PRKAG2), not by phosphorylase kinase deficiency.

P19999	MBL1_RAT	Mannose-binding protein A	10903744	Impaired secretion of rat mannose-binding protein resulting from mutations in the collagen-like domain.

Q9NZC7	WWOX_HUMAN	WW domain-containing oxidoreductase	15064722	WWOX binds the specific proline-rich ligand PPXY: identification of candidate interacting proteins.

P93788	REMO_SOLTU	Remorin	8989883	Cloning of a cDNA encoding a plasma membrane-associated, uronide binding phosphoprotein with physical properties similar to viral movement proteins.

Q93VQ9	TRXO2_ARATH	Thioredoxin O2, mitochondrial	11717467	Identification and characterization of a mitochondrial thioredoxin system in plants.

O95163	ELP1_HUMAN	Elongator complex protein 1	11818576	Human Elongator facilitates RNA polymerase II transcription through chromatin.

Q99574	NEUS_HUMAN	Neuroserpin	9070919	Human neuroserpin (PI12): cDNA cloning and chromosomal localization to 3q26.

P34078	LTV1_YEAST	Protein LTV1	16738661	Hrr25-dependent phosphorylation state regulates organization of the pre-40S subunit.

P97363	SPTC2_MOUSE	Serine palmitoyltransferase 2	9363775	Human and murine serine-palmitoyl-CoA transferase. Cloning, expression and characterization of the key enzyme in sphingolipid synthesis.

Q9BQA5	HINFP_HUMAN	Histone H4 transcription factor	15988025	HiNF-P directly links the cyclin E/CDK2/p220NPAT pathway to histone H4 gene regulation at the G1/S phase cell cycle transition.

Q04178	HPRT_YEAST	Hypoxanthine-guanine phosphoribosyltransferase	9335580	The isolation and characterization of Saccharomyces cerevisiae mutants that constitutively express purine biosynthetic genes.

P0ADV7	MLAC_ECOLI	Probable phospholipid-binding protein mlaC	19383799	An ABC transport system that maintains lipid asymmetry in the gram- negative outer membrane.

O34814	FTSE_BACSU	Cell division ATP-binding protein ftsE	18573177	The FtsEX ABC transporter directs cellular differentiation in Bacillus subtilis.

O95968	SG1D1_HUMAN	Secretoglobin family 1D member 1	10066439	Lipophilins: human peptides homologous to rat prostatein.

Q804H7	BI52B_XENLA	Baculoviral IAP repeat-containing protein 5.2-B	17199039	Chromosomal enrichment and activation of the aurora B pathway are coupled to spatially regulate spindle assembly.

Q9BQI0	AIF1L_HUMAN	Allograft inflammatory factor 1-like	18699778	Structural and functional characterization of human Iba proteins.

P12954	SRS2_YEAST	ATP-dependent DNA helicase SRS2	8419328	Purification and characterization of the SRS2 DNA helicase of the yeast Saccharomyces cerevisiae.

O74832	PT127_SCHPO	mRNA degradation protein pet127, mitochondrial	17292401	RNA degradation in fission yeast mitochondria is stimulated by a member of a new family of proteins that are conserved in lower eukaryotes.

O94587	COX18_SCHPO	Mitochondrial inner membrane protein cox18	16911509	The COX18 gene, involved in mitochondrial biogenesis, is functionally conserved and tightly regulated in humans and fission yeast.

P04179	SODM_HUMAN	Superoxide dismutase [Mn], mitochondrial	19265433	Contribution of human manganese superoxide dismutase tyrosine 34 to structure and catalysis.

Q8IFW4	THIOT_DROME	Thioredoxin-T	14579129	The ThioredoxinT and deadhead gene pair encode testis- and ovary- specific thioredoxins in Drosophila melanogaster.

P63208	SKP1_HUMAN	S-phase kinase-associated protein 1	18203720	Diversity in tissue expression, substrate binding, and SCF complex formation for a lectin family of ubiquitin ligases.

Q8I589	PPR1_PLAF7	Pentatricopeptide repeat-containing protein PFL1605w	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

Q9W6Z2	TBPL1_XENLA	TATA box-binding protein-like protein 1	17703192	TBP paralogs accommodate metazoan- and vertebrate-specific developmental gene regulation.

Q9BYV6	TRI55_HUMAN	Tripartite motif-containing protein 55	11243782	Identification of muscle specific ring finger proteins as potential regulators of the titin kinase domain.

O45962	RLE1_CAEEL	Regulation of longevity by E3 ubiquitin-protein ligase	17276341	RLE-1, an E3 ubiquitin ligase, regulates C. elegans aging by catalyzing DAF-16 polyubiquitination.

Q99735	MGST2_HUMAN	Microsomal glutathione S-transferase 2	8703034	Identification and characterization of a novel human microsomal glutathione S-transferase with leukotriene C4 synthase activity and significant sequence identity to 5-lipoxygenase-activating protein and leukotriene C4 synthase.

P47084	YJX3_YEAST	Uncharacterized protein YJR003C, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

O74331	RLP1_SCHPO	DNA repair protein rlp1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q04431	YD532_YEAST	Spindle pole body component YDR532C	14562095	Global analysis of protein localization in budding yeast.

Q03530	RCE1_YEAST	CAAX prenyl protease 2	10825201	The CaaX proteases, Afc1p and Rce1p, have overlapping but distinct substrate specificities.

D0QMC3	MNDAL_MOUSE	Myeloid cell nuclear differentiation antigen-like protein	19654412	Mndal, a new interferon-inducible family member, is highly polymorphic, suppresses cell growth, and may modify plasmacytoma susceptibility.

Q39255	SKP1A_ARATH	SKP1-like protein 1A	14749489	Expression and interaction analysis of Arabidopsis Skp1-related genes.

Q9NWW5	CLN6_HUMAN	Ceroid-lipofuscinosis neuronal protein 6	11727201	The gene mutated in variant late-infantile neuronal ceroid lipofuscinosis (CLN6) and in nclf mutant mice encodes a novel predicted transmembrane protein.

P04434	KV310_HUMAN	Ig kappa chain V-III region VH	6440122	Immunoglobulin genes of different subgroups are interdigitated within the VK locus.

Q9GRX6	AIFM1_DICDI	Apoptosis-inducing factor 1, mitochondrial	11598188	On the evolutionary conservation of the cell death pathway: mitochondrial release of an apoptosis-inducing factor during Dictyostelium discoideum cell death.

P30531	SC6A1_HUMAN	Sodium- and chloride-dependent GABA transporter 1	2387399	Cloning of the human brain GABA transporter.

P09217	KPCZ_RAT	Protein kinase C zeta type	12813044	Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins.

P33595	SGRR_ECOLI	HTH-type transcriptional regulator sgrR	15522088	Involvement of a novel transcriptional activator and small RNA in post-transcriptional regulation of the glucose phosphoenolpyruvate phosphotransferase system.

P39726	GCSH_YEAST	Glycine cleavage system H protein, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q8ST83	PHO_DROME	Polycomb protein PHO	10433918	The DNA-binding Polycomb group protein pleiohomeotic mediates silencing of a Drosophila homeotic gene.

Q9Y5P4	C43BP_HUMAN	Collagen type IV alpha-3-binding protein	11007769	Goodpasture antigen-binding protein, the kinase that phosphorylates the Goodpasture antigen, is an alternatively spliced variant implicated in autoimmune pathogenesis.

Q9V3N2	OR46B_DROME	Odorant receptor 46a, isoform B	10089887	A spatial map of olfactory receptor expression in the Drosophila antenna.

Q14106	TOB2_HUMAN	Protein Tob2	10602502	Tob2, a novel anti-proliferative Tob/BTG1 family member, associates with a component of the CCR4 transcriptional regulatory complex capable of binding cyclin-dependent kinases.

P06536	GCR_RAT	Glucocorticoid receptor	12917342	BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation.

P48995	TRPC1_HUMAN	Short transient receptor potential channel 1	15757897	MxA, a member of the dynamin superfamily, interacts with the ankyrin- like repeat domain of TRPC.

O64903	NDK2_ARATH	Nucleoside diphosphate kinase II, chloroplastic	15465053	Structural analysis of Arabidopsis thaliana nucleoside diphosphate kinase-2 for phytochrome-mediated light signaling.

Q9VFS5	PP4R3_DROME	Serine/threonine-protein phosphatase 4 regulatory subunit 3	19204120	Protein phosphatase 4 mediates localization of the Miranda complex during Drosophila neuroblast asymmetric divisions.

P49762	DOA_DROME	Serine/threonine-protein kinase Doa	11014821	The LAMMER protein kinase encoded by the Doa locus of Drosophila is required in both somatic and germline cells and is expressed as both nuclear and cytoplasmic isoforms throughout development.

Q14973	NTCP_HUMAN	Sodium/bile acid cotransporter	8132774	Molecular cloning, chromosomal localization, and functional characterization of a human liver Na+/bile acid cotransporter.

O59829	YCU9_SCHPO	Probable nitrilase C965.09	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q03557	GATH_YEAST	Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial	11914276	Subcellular localization of the yeast proteome.

Q9UBQ7	GRHPR_HUMAN	Glyoxylate reductase/hydroxypyruvate reductase	10484776	The gene encoding hydroxypyruvate reductase (GRHPR) is mutated in patients with primary hyperoxaluria type II.

Q9Y2X9	ZN281_HUMAN	Zinc finger protein 281	10448078	ZBP-99 defines a conserved family of transcription factors and regulates ornithine decarboxylase gene expression.

P87227	MIS6_SCHPO	Inner centromere protein mis6	12719471	Sim4: a novel fission yeast kinetochore protein required for centromeric silencing and chromosome segregation.

P85213	DEF1_GALME	Defensin	14728668	Purification, cDNA cloning and expression of an insect defensin from the great wax moth, Galleria mellonella.

Q94527	NFKB1_DROME	Nuclear factor NF-kappa-B p110 subunit	11269502	The Drosophila caspase Dredd is required to resist Gram-negative bacterial infection.

Q9V3I5	JIL1_DROME	Chromosomal serine/threonine-protein kinase JIL-1	10831604	JIL-1, a chromosomal kinase implicated in regulation of chromatin structure, associates with the male specific lethal (MSL) dosage compensation complex.

O35260	NACC1_RAT	Nucleus accumbens-associated protein 1	17254023	NAC1, a cocaine-regulated POZ/BTB protein interacts with CoREST.

Q9XJ35	CLPR1_ARATH	ATP-dependent Clp protease proteolytic subunit-related protein 1, chloroplastic	10427773	Identification of clp genes expressed in senescing Arabidopsis leaves.

Q03614	NTDO_CAEEL	Sodium-dependent dopamine transporter	9765501	The Caenorhabditis elegans gene T23G5.5 encodes an antidepressant- and cocaine-sensitive dopamine transporter.

Q6IFV1	K1C14_RAT	Keratin, type I cytoskeletal 14	8950218	Identification of cytokeratin subspecies altered in rat experimental esophageal tumors by subtractive cloning.

P51142	DVL2_XENLA	Segment polarity protein dishevelled homolog DVL-2	12699625	The prickle-related gene in vertebrates is essential for gastrulation cell movements.

Q9BRK5	CAB45_HUMAN	45 kDa calcium-binding protein	17442889	A cytosolic splice variant of Cab45 interacts with Munc18b and impacts on amylase secretion by pancreatic acini.

Q9JJT0	RCL1_MOUSE	RNA 3'-terminal phosphate cyclase-like protein	10790377	Rcl1p, the yeast protein similar to the RNA 3'-phosphate cyclase, associates with U3 snoRNP and is required for 18S rRNA biogenesis.

O97148	MTH_DROME	G-protein coupled receptor Mth	10995474	Adaptive evolution of a candidate gene for aging in Drosophila.

P55863	SOX3A_XENLA	Transcription factor Sox-3-A	17608734	The Sox axis, Nodal signaling, and germ layer specification.

O43251	RBM9_HUMAN	RNA-binding protein 9	11875103	A negative coregulator for the human ER.

P53379	MKC7_YEAST	Aspartic proteinase MKC7	7479877	Shared functions in vivo of a glycosyl-phosphatidylinositol-linked aspartyl protease, Mkc7, and the proprotein processing protease Kex2 in yeast.

Q90259	ASL1A_DANRE	Achaete-scute homolog 1a	12702659	Ash1a and neurogenin1 function downstream of floating head to regulate epiphysial neurogenesis.

Q9NSC5	HOME3_HUMAN	Homer protein homolog 3	10653696	Molecular characterisation of two structurally distinct groups of human homers, generated by extensive alternative splicing.

Q39233	SYP21_ARATH	Syntaxin-21	10504581	The pre-vacuolar t-SNARE AtPEP12p forms a 20S complex that dissociates in the presence of ATP.

Q12207	NCE2_YEAST	Non-classical export protein 2	8655575	A new pathway for protein export in Saccharomyces cerevisiae.

Q9P6M3	MIS14_SCHPO	Kinetochore protein mis14	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q64244	CD38_RAT	ADP-ribosyl cyclase 1	10477767	CD38/ADP-ribosyl cyclase: a new role in the regulation of osteoclastic bone resorption.

Q9H4L4	SENP3_HUMAN	Sentrin-specific protease 3	15960975	Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

P39905	GDNF_HUMAN	Glial cell line-derived neurotrophic factor	8493557	GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons.

P28902	GUC2A_RAT	Guanylin	1346555	Guanylin: an endogenous activator of intestinal guanylate cyclase.

P32447	ASF1_YEAST	Histone chaperone ASF1	15840725	Structural basis for the interaction of Asf1 with histone H3 and its functional implications.

P51513	NOVA1_HUMAN	RNA-binding protein Nova-1	8398153	Nova, the paraneoplastic Ri antigen, is homologous to an RNA-binding protein and is specifically expressed in the developing motor system.

O80340	ERF78_ARATH	Ethylene-responsive transcription factor 4	16429262	AtSAP18, an orthologue of human SAP18, is involved in the regulation of salt stress and mediates transcriptional repression in Arabidopsis.

Q12092	ATG29_YEAST	Autophagy-related protein 29	14562095	Global analysis of protein localization in budding yeast.

P61798	APTX_CHICK	Aprataxin	16964241	The neurodegenerative disease protein aprataxin resolves abortive DNA ligation intermediates.

Q7YW31	CTR1_OCTVU	Cephalotocin receptor 1	15504101	Novel evolutionary lineages of the invertebrate oxytocin/vasopressin superfamily peptides and their receptors in the common octopus (Octopus vulgaris).

P22579	SIN3_YEAST	Transcriptional regulatory protein SIN3	10388812	A general requirement for the Sin3-Rpd3 histone deacetylase complex in regulating silencing in Saccharomyces cerevisiae.

Q9UIK5	TEFF2_HUMAN	Tomoregulin-2	10903839	Identification and characterization of TMEFF2, a novel survival factor for hippocampal and mesencephalic neurons.

Q3E757	RL11B_YEAST	60S ribosomal protein L11-B	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

P37291	GLYC_YEAST	Serine hydroxymethyltransferase, cytosolic	8132653	Cloning and molecular characterization of three genes, including two genes encoding serine hydroxymethyltransferases, whose inactivation is required to render yeast auxotrophic for glycine.

P18869	LEU3_SCHPO	3-isopropylmalate dehydrogenase	3063400	The primary structure of the leu1+ gene of Schizosaccharomyces pombe.

Q96BH1	RNF25_HUMAN	E3 ubiquitin-protein ligase RNF25	12748188	RING finger protein AO7 supports NF-kappaB-mediated transcription by interacting with the transactivation domain of the p65 subunit.

P40529	AGE2_YEAST	ADP-ribosylation factor GTPase-activating protein effector protein 2	14562095	Global analysis of protein localization in budding yeast.

P82932	RT06_HUMAN	28S ribosomal protein S6, mitochondrial	11279123	The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present.

O14064	BIR1_SCHPO	Protein bir1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8R4K8	PAPP1_MOUSE	Pappalysin-1	11985604	Expression of recombinant murine pregnancy-associated plasma protein- A (PAPP-A) and a novel variant (PAPP-Ai) with differential proteolytic activity.

Q04748	SOV1_YEAST	Protein SOV1, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

Q9VHN9	HPS5_DROME	Hermansky-Pudlak syndrome 5 protein homolog	17632576	The pink gene encodes the Drosophila orthologue of the human Hermansky-Pudlak syndrome 5 (HPS5) gene.

P38620	KPR2_YEAST	Ribose-phosphate pyrophosphokinase 2	15280369	Heterooligomeric phosphoribosyl diphosphate synthase of Saccharomyces cerevisiae: combinatorial expression of the five PRS genes in Escherichia coli.

Q24572	CAF1_DROME	Probable histone-binding protein Caf1	11124122	The Drosophila polycomb group proteins ESC and E(Z) are present in a complex containing the histone-binding protein p55 and the histone deacetylase RPD3.

P43246	MSH2_HUMAN	DNA mismatch repair protein Msh2	11555625	Functional analysis of human MLH1 and MSH2 missense variants and hybrid human-yeast MLH1 proteins in Saccharomyces cerevisiae.

Q03701	CEBPZ_HUMAN	CCAAT/enhancer-binding protein zeta	2247079	A cloned human CCAAT-box-binding factor stimulates transcription from the human hsp70 promoter.

P84773	BRK_AMICA	[Trp5]-bradykinin	7651903	Isolation and biological activity of [Trp5]bradykinin from the plasma of the phylogenetically ancient fish, the bowfin and the longnosed gar.

Q02248	CTNB1_MOUSE	Catenin beta-1	19458197	Scribble interacts with beta-catenin to localize synaptic vesicles to synapses.

P82271	RTD1B_MACMU	Rhesus theta defensin-1/2 subunit B	10521339	A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alpha-defensins.

Q9P6P0	TAF3_SCHPO	Transcription initiation factor TFIID subunit 3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P25439	BRM_DROME	ATP-dependent helicase brm	12381660	Histone chaperone ASF1 cooperates with the Brahma chromatin- remodelling machinery.

Q9P6M0	SLX4_SCHPO	Structure-specific endonuclease subunit slx4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P38935	SMBP2_HUMAN	DNA-binding protein SMUBP-2	19158098	IGHMBP2 is a ribosome-associated helicase inactive in the neuromuscular disorder distal SMA type 1 (DSMA1).

Q16539	MK14_HUMAN	Mitogen-activated protein kinase 14	16751104	p38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation.

P21291	CSRP1_HUMAN	Cysteine and glycine-rich protein 1	1374386	Human cysteine-rich protein. A member of the LIM/double-finger family displaying coordinate serum induction with c-myc.

Q93V78	TMT1_BRAOL	Thiocyanate methyltransferase 1	12369626	Cloning and functional expression of two plant thiol methyltransferases: a new class of enzymes involved in the biosynthesis of sulfur volatiles.

P31107	DMS2_PHYBI	Adenoregulin	15766883	Expression and purification of antimicrobial peptide adenoregulin with C-amidated terminus in Escherichia coli.

Q6UFS5	ZN503_DANRE	Zinc finger protein 503	14709556	Isolation of nlz2 and characterization of essential domains in Nlz family proteins.

Q9H9T3	ELP3_HUMAN	Elongator complex protein 3	11714725	Purification and characterization of the human elongator complex.

Q7LFX5	CHSTF_HUMAN	Carbohydrate sulfotransferase 15	11572857	Human N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase cDNA is related to human B cell recombination activating gene-associated gene.

Q07824	TPO1_YEAST	Polyamine transporter 1	12562762	Localization and function of the yeast multidrug transporter Tpo1p.

Q9VE00	C12A4_DROME	Probable cytochrome P450 12a4, mitochondrial	16120680	Cyp12a4 confers lufenuron resistance in a natural population of Drosophila melanogaster.

P32597	STH1_YEAST	Nuclear protein STH1/NPS1	12697820	The yeast RSC chromatin-remodeling complex is required for kinetochore function in chromosome segregation.

P34446	PAT2_CAEEL	Integrin alpha pat-2	12915588	Talin loss-of-function uncovers roles in cell contractility and migration in C. elegans.

Q9H320	VCX1_HUMAN	Variable charge X-linked protein 1	10607842	A human sex-chromosomal gene family expressed in male germ cells and encoding variably charged proteins.

Q19706	EIF3G_CAEEL	Eukaryotic translation initiation factor 3 subunit G	12529635	Systematic functional analysis of the Caenorhabditis elegans genome using RNAi.

P21672	RIR3_YEAST	Ribonucleoside-diphosphate reductase large chain 2	12732713	Subcellular localization of yeast ribonucleotide reductase regulated by the DNA replication and damage checkpoint pathways.

O57437	DAZLA_XENLA	Deleted in azoospermia-like-A	11784096	Three-dimensional ultrastructural analysis of RNA distribution within germinal granules of Xenopus.

P54144	AMT11_ARATH	Ammonium transporter 1 member 1	16917981	Role of AMT1;1 in NH4+ acquisition in Arabidopsis thaliana.

O15297	PPM1D_HUMAN	Protein phosphatase 1D	9177166	Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner.

O75935	DCTN3_HUMAN	Dynactin subunit 3	9722614	Characterization of the p22 subunit of dynactin reveals the localization of cytoplasmic dynein and dynactin to the midbody of dividing cells.

Q9QZS3	NUMB_MOUSE	Protein numb homolog	11782429	LNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradation.

O94637	KAE1_SCHPO	Putative glycoprotein endopeptidase kae1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q07879	ATG10_YEAST	Ubiquitin-like-conjugating enzyme ATG10	10508157	Apg10p, a novel protein-conjugating enzyme essential for autophagy in yeast.

P30290	MIK1_SCHPO	Mitosis inhibitor protein kinase mik1	1706223	mik1 and wee1 cooperate in the inhibitory tyrosine phosphorylation of cdc2.

Q9FFN1	PP363_ARATH	Pentatricopeptide repeat-containing protein At5g03800	15647901	Arabidopsis emb175 and other ppr knockout mutants reveal essential roles for pentatricopeptide repeat (PPR) proteins in plant embryogenesis.

P77214	CUSF_ECOLI	Cation efflux system protein cusF	12813074	Molecular analysis of the copper-transporting efflux system CusCFBA of Escherichia coli.

Q9UKG9	OCTC_HUMAN	Peroxisomal carnitine O-octanoyltransferase	10486279	Molecular cloning and expression of human carnitine octanoyltransferase: evidence for its role in the peroxisomal beta- oxidation of branched-chain fatty acids.

P31652	SC6A4_RAT	Sodium-dependent serotonin transporter	16870614	Subcellular redistribution of the serotonin transporter by secretory carrier membrane protein 2.

P20425	KCY_DICDI	Cytidylate kinase	2156849	cDNA-derived sequence of UMP-CMP kinase from Dictyostelium discoideum and expression of the enzyme in Escherichia coli.

P70604	KCNN2_RAT	Small conductance calcium-activated potassium channel protein 2	11323678	Structure of the gating domain of a Ca2+-activated K+ channel complexed with Ca2+/calmodulin.

P63005	LIS1_MOUSE	Platelet-activating factor acetylhydrolase IB subunit alpha	14507966	Disregulated RhoGTPases and actin cytoskeleton contribute to the migration defect in Lis1-deficient neurons.

Q94F88	CMT3_ARATH	DNA (cytosine-5)-methyltransferase CMT3	11349138	Requirement of CHROMOMETHYLASE3 for maintenance of CpXpG methylation.

P77690	ARNB_ECOLI	UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase	12704196	Origin of lipid A species modified with 4-amino-4-deoxy-L-arabinose in polymyxin-resistant mutants of Escherichia coli. An aminotransferase (ArnB) that generates UDP-4-deoxyl-L-arabinose.

Q06151	DCPS_YEAST	Scavenger mRNA-decapping enzyme DcpS	14562095	Global analysis of protein localization in budding yeast.

P38811	TRA1_YEAST	Transcription-associated protein 1	12446794	The novel SLIK histone acetyltransferase complex functions in the yeast retrograde response pathway.

Q92643	GPI8_HUMAN	GPI-anchor transamidase	11483512	PIG-S and PIG-T, essential for GPI anchor attachment to proteins, form a complex with GAA1 and GPI8.

P50747	BPL1_HUMAN	Biotin--protein ligase	7842009	Isolation and characterization of mutations in the human holocarboxylase synthetase cDNA.

P22980	MYOD1_CAEEL	Myoblast determination protein 1 homolog	2175254	CeMyoD accumulation defines the body wall muscle cell fate during C. elegans embryogenesis.

P11353	HEM6_YEAST	Coproporphyrinogen-III oxidase	2838478	Isolation, sequence, and regulation by oxygen of the yeast HEM13 gene coding for coproporphyrinogen oxidase.

Q63487	RRAGB_RAT	Ras-related GTP-binding protein B	7499430	Cloning of a novel family of mammalian GTP-binding proteins (RagA, RagBs, RagBl) with remote similarity to the Ras-related GTPases.

P61353	RL27_HUMAN	60S ribosomal protein L27	8148381	Cloning and nucleotide sequence of a full length cDNA encoding ribosomal protein L27 from human fetal kidney.

Q13232	NDK3_HUMAN	Nucleoside diphosphate kinase 3	7638209	Overexpression of DR-nm23, a protein encoded by a member of the nm23 gene family, inhibits granulocyte differentiation and induces apoptosis in 32Dc13 myeloid cells.

Q10586	DBP_HUMAN	D site-binding protein	8786133	Genomic structure of the human D-site binding protein (DBP) gene.

P43637	TOS3_YEAST	Serine/threonine-protein kinase TOS3	12847291	Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases.

Q5RKZ7	MOCS1_MOUSE	Molybdenum cofactor biosynthesis protein 1	17236133	Long-term rescue of a lethal inherited disease by adeno-associated virus-mediated gene transfer in a mouse model of molybdenum-cofactor deficiency.

Q9C8Y3	RGL1_ARATH	DELLA protein RGL1	11826301	Arabidopsis RGL1 encodes a negative regulator of gibberellin responses.

P40026	KRE29_YEAST	DNA repair protein KRE29	15738391	A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization.

Q02206	RSC4_YEAST	Chromatin structure-remodeling complex subunit RSC4	12183366	Chromatin remodeling by RSC involves ATP-dependent DNA translocation.

Q12959	DLG1_HUMAN	Disks large homolog 1	15302935	Large-scale characterization of HeLa cell nuclear phosphoproteins.

Q80U87	UBP8_MOUSE	Ubiquitin carboxyl-terminal hydrolase 8	16120644	Regulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomes.

Q9NS00	C1GLT_HUMAN	Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1	11677243	Cloning and expression of human core 1 beta1,3- galactosyltransferase.

O75426	FBX24_HUMAN	F-box only protein 24	10531035	Identification of a family of human F-box proteins.

Q38FA5	RLGM1_TRYBB	RNA-editing ligase 1, mitochondrial	11251122	An RNA ligase essential for RNA editing and survival of the bloodstream form of Trypanosoma brucei.

Q03414	MEF2A_XENLA	Myocyte-specific enhancer factor 2A homolog	7813786	Activation of Xenopus MyoD transcription by members of the MEF2 protein family.

P84510	TX3_PARSR	Beta-theraphotoxin-Ps1a	16267209	Four novel tarantula toxins as selective modulators of voltage-gated sodium channel subtypes.

Q8CBD1	NRIP1_MOUSE	Nuclear receptor-interacting protein 1	15879431	Post-translational modification of nuclear co-repressor receptor- interacting protein 140 by acetylation.

Q9BT22	ALG1_HUMAN	Chitobiosyldiphosphodolichol beta-mannosyltransferase	10704531	Cloning of the human cDNA which can complement the defect of the yeast mannosyltransferase I-deficient mutant alg 1.

P40259	CD79B_HUMAN	B-cell antigen receptor complex-associated protein beta chain	8486355	Isolation and chromosomal mapping of the human immunoglobulin- associated B29 gene (IGB).

P48552	NRIP1_HUMAN	Nuclear receptor-interacting protein 1	14736873	Characterization of four autonomous repression domains in the corepressor receptor interacting protein 140.

Q6Q560	ISD11_YEAST	Protein ISD11	16341090	The Nfs1 interacting protein Isd11 has an essential role in Fe/S cluster biogenesis in mitochondria.

Q9Y2X0	MED16_HUMAN	Mediator of RNA polymerase II transcription subunit 16	10235266	Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex.

Q6Y1H2	HACD2_HUMAN	3-hydroxyacyl-CoA dehydratase 2	15024066	The yeast split-ubiquitin membrane protein two-hybrid screen identifies BAP31 as a regulator of the turnover of endoplasmic reticulum-associated protein tyrosine phosphatase-like B.

P28288	ABCD3_HUMAN	ATP-binding cassette sub-family D member 3	10551832	Homo- and heterodimerization of peroxisomal ATP-binding cassette half-transporters.

Q8CG09	MRP1_RAT	Multidrug resistance-associated protein 1	12423064	Cloning and characterization of the rat multidrug resistance- associated protein 1.

O95678	K2C75_HUMAN	Keratin, type II cytoskeletal 75	9856802	A novel human type II cytokeratin, K6hf, specifically expressed in the companion layer of the hair follicle.

P40343	VPS27_YEAST	Vacuolar protein sorting-associated protein 27	9702203	Phosphatidylinositol(3)-phosphate signaling mediated by specific binding to RING FYVE domains.

P12643	BMP2_HUMAN	Bone morphogenetic protein 2	3201241	Novel regulators of bone formation: molecular clones and activities.

O89026	ROBO1_MOUSE	Roundabout homolog 1	15091338	Conserved roles for slit and robo proteins in midline commissural axon guidance.

P38636	ATX1_YEAST	Metal homeostasis factor ATX1	7731983	The ATX1 gene of Saccharomyces cerevisiae encodes a small metal homeostasis factor that protects cells against reactive oxygen toxicity.

P46153	GATA6_RAT	Transcription factor GATA-6	8248184	Gastric DNA-binding proteins recognize upstream sequence motifs of parietal cell-specific genes.

Q16719	KYNU_HUMAN	Kynureninase	9180257	Cloning and recombinant expression of rat and human kynureninase.

Q7KQZ4	LOLA3_DROME	Longitudinals lacking protein, isoforms A/B/D/L	8050351	Lola encodes a putative transcription factor required for axon growth and guidance in Drosophila.

Q8VDL9	GLIS2_MOUSE	Zinc finger protein GLIS2	11262234	Identification of NKL, a novel Gli-Kruppel zinc-finger protein that promotes neuronal differentiation.

Q8TFH5	YIK9_SCHPO	Meiotically up-regulated protein PB17E12.09	12161753	The transcriptional program of meiosis and sporulation in fission yeast.

P42127	ASIP_HUMAN	Agouti-signaling protein	7757071	Structure and function of ASP, the human homolog of the mouse agouti gene.

P04803	SYWM_YEAST	Tryptophanyl-tRNA synthetase, mitochondrial	2999114	MSW, a yeast gene coding for mitochondrial tryptophanyl-tRNA synthetase.

O00241	SIRB1_HUMAN	Signal-regulatory protein beta-1	10940905	Association of signal-regulatory proteins beta with KARAP/DAP-12.

Q04721	NOTC2_HUMAN	Neurogenic locus notch homolog protein 2	9244302	Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane.

P04406	G3P_HUMAN	Glyceraldehyde-3-phosphate dehydrogenase	3170585	Isolation and complete sequence of a functional human glyceraldehyde- 3-phosphate dehydrogenase gene.

O42973	YGZ3_SCHPO	Uncharacterized protein C20F10.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O43000	LIZ1_SCHPO	Pantothenate transporter liz1	9950674	Liz1p, a novel fission yeast membrane protein, is required for normal cell division when ribonucleotide reductase is inhibited.

P84271	DAH55_LITDA	Dahlein-5.5	11555873	Bioactive dahlein peptides from the skin secretions of the Australian aquatic frog Litoria dahlii: sequence determination by electrospray mass spectrometry.

Q12805	FBLN3_HUMAN	EGF-containing fibulin-like extracellular matrix protein 1	19275936	ECM1 interacts with fibulin-3 and the beta 3 chain of laminin 332 through its serum albumin subdomain-like 2 domain.

Q9SEI2	PS6AA_ARATH	26S protease regulatory subunit 6A homolog A	19223514	The Arabidopsis proteasome RPT5 subunits are essential for gametophyte development and show accession-dependent redundancy.

Q09161	NCBP1_HUMAN	Nuclear cap-binding protein subunit 1	17873884	Failsafe nonsense-mediated mRNA decay does not detectably target eIF4E-bound mRNA.

Q9H7L9	SDS3_HUMAN	Sin3 histone deacetylase corepressor complex component SDS3	12670868	Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell- proliferation factor HCF-1.

P38715	GRE3_YEAST	NADPH-dependent aldose reductase GRE3	11525399	The Saccharomyces cerevisiae aldose reductase is implied in the metabolism of methylglyoxal in response to stress conditions.

Q9W0G1	PTP61_DROME	Tyrosine-protein phosphatase non-receptor type 61F	8663600	A Drosophila protein-tyrosine phosphatase associates with an adapter protein required for axonal guidance.

Q3KQ35	S17AA_XENLA	Transcription factor Sox-17-alpha-A	15163629	Sox17 and beta-catenin cooperate to regulate the transcription of endodermal genes.

P32834	SXA1_SCHPO	Aspartic proteinase sxa1	1549128	Schizosaccharomyces pombe sxa1+ and sxa2+ encode putative proteases involved in the mating response.

Q12150	CSF1_YEAST	Protein CSF1	10781556	Cloning and characterization of the CSF1 gene of Saccharomyces cerevisiae, which is required for nutrient uptake at low temperature.

P75905	PGAC_ECOLI	Poly-beta-1,6-N-acetyl-D-glucosamine synthase	18359807	Roles of pgaABCD genes in synthesis, modification, and export of the Escherichia coli biofilm adhesin poly-beta-1,6-N-acetyl-D- glucosamine.

P63220	RS21_HUMAN	40S ribosomal protein S21	8332502	Primary structure of human ribosomal protein S21.

Q12208	YL132_YEAST	Uncharacterized protein YLR132C	14562095	Global analysis of protein localization in budding yeast.

O45818	DKF2_CAEEL	Serine/threonine-protein kinase dkf-2	19371715	Protein kinase D is an essential regulator of C. elegans innate immunity.

Q9SLF3	TC132_ARATH	Translocase of chloroplast 132, chloroplastic	10646606	The major protein import receptor of plastids is essential for chloroplast biogenesis.

P49333	ETR1_ARATH	Ethylene receptor 1	15703053	Ethylene-binding activity, gene expression levels, and receptor system output for ethylene receptor family members from Arabidopsis and tomato.

O74323	SEC11_SCHPO	Signal peptidase complex catalytic subunit sec11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P60571	PANX2_RAT	Pannexin-2	14597722	Pannexins, a family of gap junction proteins expressed in brain.

Q2QCI8	MED12_DANRE	Mediator of RNA polymerase II transcription subunit 12	16344459	The zebrafish kohtalo/trap230 gene is required for the development of the brain, neural crest, and pronephric kidney.

Q94F62	BAK1_ARATH	BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1	17583510	The BRI1-associated kinase 1, BAK1, has a brassinolide-independent role in plant cell-death control.

P35240	MERL_HUMAN	Merlin	19144871	Identification of erythrocyte p55/MPP1 as a binding partner of NF2 tumor suppressor protein/Merlin.

P96206	DRRB_MYCTU	Doxorubicin resistance ABC transporter permease protein drrB	12057006	Overexpression and functional characterization of an ABC (ATP-binding cassette) transporter encoded by the genes drrA and drrB of Mycobacterium tuberculosis.

Q9VD74	GR93C_DROME	Putative gustatory receptor 93c	10710312	Candidate taste receptors in Drosophila.

Q12167	YD065_YEAST	Uncharacterized protein YDR065W	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Q96I23	PREY_HUMAN	Protein preY, mitochondrial	16162815	The initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-Y, a seventh component.

O74783	POF2_SCHPO	SCF E3 ubiquitin ligase complex F-box protein pof2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P78926	MAP1_SCHPO	Pheromone receptor transcription activator	8668157	Schizosaccharomyces pombe map1+ encodes a MADS-box-family protein required for cell-type-specific gene expression.

P22810	HMOC_DROME	Homeotic protein ocelliless	8575625	orthodenticle is required for photoreceptor cell development in the Drosophila eye.

Q9C0V1	AMT1_SCHPO	Ammonium transporter 1	16999738	Ammonium transporter genes in the fission yeast Schizosaccharomyces pombe: role in ammonium uptake and a morphological transition.

P22219	VPS15_YEAST	Serine/threonine-protein kinase VPS15	7989323	Vps34p required for yeast vacuolar protein sorting is a multiple specificity kinase that exhibits both protein kinase and phosphatidylinositol-specific PI 3-kinase activities.

Q9Y091	FL2D_DROME	Pre-mRNA-splicing regulator female-lethal(2)D	10790389	The Drosophila fl(2)d gene, required for female-specific splicing of Sxl and tra pre-mRNAs, encodes a novel nuclear protein with a HQ-rich domain.

P24890	CYB_CAEEL	Cytochrome b	1551572	The mitochondrial genomes of two nematodes, Caenorhabditis elegans and Ascaris suum.

Q16610	ECM1_HUMAN	Extracellular matrix protein 1	19275936	ECM1 interacts with fibulin-3 and the beta 3 chain of laminin 332 through its serum albumin subdomain-like 2 domain.

Q94901	LARK_DROME	RNA-binding protein lark	15452872	The Drosophila RNA-binding protein Lark is required for the organization of the actin cytoskeleton and Hu-li tai shao localization during oogenesis.

Q8NHZ8	CDC26_HUMAN	Anaphase-promoting complex subunit CDC26	10922056	The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex.

Q9CWU2	ZDH13_MOUSE	Palmitoyltransferase ZDHHC13	18794299	Huntingtin-interacting proteins, HIP14 and HIP14L, mediate dual functions, palmitoyl acyltransferase and Mg2+ transport.

Q9VA12	PSA4L_DROME	Proteasome subunit alpha type-4-like	12421421	Expression of proteasome subunit isoforms during spermatogenesis in Drosophila melanogaster.

P49753	ACOT2_HUMAN	Acyl-coenzyme A thioesterase 2, mitochondrial	10944470	Identification of PTE2, a human peroxisomal long-chain acyl-CoA thioesterase.

Q9HC29	NOD2_HUMAN	Nucleotide-binding oligomerization domain-containing protein 2	11087742	Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB.

P52496	DNLI4_CANAL	DNA ligase 4	11119499	Phenotypic analysis and virulence of Candida albicans LIG4 mutants.

P53350	PLK1_HUMAN	Serine/threonine-protein kinase PLK1	19596235	Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair.

Q14190	SIM2_HUMAN	Single-minded homolog 2	9199934	Cloning of two human homologs of the Drosophila single-minded gene SIM1 on chromosome 6q and SIM2 on 21q within the Down syndrome chromosomal region.

Q8J0I9	GUN16_TRIHA	Endo-1,6-beta-D-glucanase BGN16.3	15982190	BGN16.3, a novel acidic beta-1,6-glucanase from mycoparasitic fungus Trichoderma harzianum CECT 2413.

Q9EQ09	OLR1_MOUSE	Oxidized low-density lipoprotein receptor 1	9588202	High affinity binding of oxidized LDL to mouse lectin-like oxidized LDL receptor (LOX-1).

P43572	EPL1_YEAST	Enhancer of polycomb-like protein 1	12782659	Yeast enhancer of polycomb defines global Esa1-dependent acetylation of chromatin.

P38797	PP2C7_YEAST	Protein phosphatase 2C homolog 7, mitochondrial	11327310	Molecular analysis of the Saccharomyces cerevisiae YHR076w gene.

Q9VW97	LSDA_DROME	Possible lysine-specific histone demethylase 1	17434130	Heterochromatin formation in Drosophila is initiated through active removal of H3K4 methylation by the LSD1 homolog SU(VAR)3-3.

P49959	MRE11_HUMAN	Double-strand break repair protein MRE11A	9651580	The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks.

Q3TI53	SCHI1_MOUSE	Schwannomin-interacting protein 1	10669747	Cloning and characterization of SCHIP-1, a novel protein interacting specifically with spliced isoforms and naturally occurring mutant NF2 proteins.

P19938	DAAA_BACYM	D-alanine aminotransferase	2914916	Thermostable D-amino acid aminotransferase from a thermophilic Bacillus species. Purification, characterization, and active site sequence determination.

Q01939	PRS8_YEAST	26S protease regulatory subunit 8 homolog	10688918	Physical association of ubiquitin ligases and the 26S proteasome.

Q42510	EMB30_ARATH	Pattern formation protein EMB30	8020095	EMB30 is essential for normal cell division, cell expansion, and cell adhesion in Arabidopsis and encodes a protein that has similarity to Sec7.

P02829	HSP82_YEAST	ATP-dependent molecular chaperone HSP82	14718169	The Mechanism of Hsp90 regulation by the protein kinase-specific cochaperone p50(cdc37).

Q9Z2A6	MK15_RAT	Mitogen-activated protein kinase 15	9891064	Extracellular signal-regulated kinase 7 (ERK7), a novel ERK with a C- terminal domain that regulates its activity, its cellular localization, and cell growth.

Q62668	UT2_RAT	Urea transporter 2	17702749	The UT-A1 urea transporter interacts with snapin, a SNARE-associated protein.

P52286	SKP1_YEAST	Suppressor of kinetochore protein 1	8706131	SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box.

Q9USY4	ABP2_SCHPO	ARS-binding protein 2	9488484	Isolation, characterization, and molecular cloning of a protein (Abp2) that binds to a Schizosaccharomyces pombe origin of replication (ars3002).

Q54NP6	SNAA_DICDI	Alpha-soluble NSF attachment protein	12175335	Syntaxin 7, syntaxin 8, Vti1 and VAMP7 (vesicle-associated membrane protein 7) form an active SNARE complex for early macropinocytic compartment fusion in Dictyostelium discoideum.

Q61171	PRDX2_MOUSE	Peroxiredoxin-2	9115640	Murine thioredoxin peroxidase delays neuronal apoptosis and is expressed in areas of the brain most susceptible to hypoxic and ischemic injury.

P30876	RPB2_HUMAN	DNA-directed RNA polymerase II subunit RPB2	9852112	Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.

P48566	GYP3_YEAST	GTPase-activating protein GYP3	10679030	Identification of novel, evolutionarily conserved Cdc42p-interacting proteins and of redundant pathways linking Cdc24p and Cdc42p to actin polarization in yeast.

P07687	HYEP_RAT	Epoxide hydrolase 1	3032949	Structure and organization of the microsomal xenobiotic epoxide hydrolase gene.

Q9NBD7	CLASP_DROME	CLIP-associating protein	15240569	Mutations in orbit/mast reveal that the central spindle is comprised of two microtubule populations, those that initiate cleavage and those that propagate furrow ingression.

P53082	YGX0_YEAST	Uncharacterized bolA-like protein YGL220W	14562095	Global analysis of protein localization in budding yeast.

P11940	PABP1_HUMAN	Polyadenylate-binding protein 1	2885805	Human mRNA polyadenylate binding protein: evolutionary conservation of a nucleic acid binding motif.

P84774	BRK_LEPOS	[Trp5]-bradykinin	7651903	Isolation and biological activity of [Trp5]bradykinin from the plasma of the phylogenetically ancient fish, the bowfin and the longnosed gar.

Q8LHH9	SHL2_ORYSJ	Probable RNA-dependent RNA polymerase SHL2	17804793	The small interfering RNA production pathway is required for shoot meristem initiation in rice.

Q07555	YD129_YEAST	Uncharacterized protein YDL129W	14562095	Global analysis of protein localization in budding yeast.

O13688	NSE6_SCHPO	Non-structural maintenance of chromosome element 6	16478984	The Nse5-Nse6 dimer mediates DNA repair roles of the Smc5-Smc6 complex.

P32115	PAX4_MOUSE	Paired box protein Pax-4	10567552	Paired-homeodomain transcription factor PAX4 acts as a transcriptional repressor in early pancreatic development.

Q16540	RM23_HUMAN	39S ribosomal protein L23, mitochondrial	8541832	A novel L23-related gene 40 kb downstream of the imprinted H19 gene is biallelically expressed in mid-fetal and adult human tissues.

Q08830	FGL1_HUMAN	Fibrinogen-like protein 1	8390249	Molecular cloning and initial characterization of a novel fibrinogen- related gene, HFREP-1.

Q9LJD7	COP10_ARATH	Constitutive photomorphogenesis protein 10	11877375	Arabidopsis COP10 is a ubiquitin-conjugating enzyme variant that acts together with COP1 and the COP9 signalosome in repressing photomorphogenesis.

P84785	DEF_PHACN	Defensin-like protein	15572193	Coccinin, an antifungal peptide with antiproliferative and HIV-1 reverse transcriptase inhibitory activities from large scarlet runner beans.

Q9NPJ6	MED4_HUMAN	Mediator of RNA polymerase II transcription subunit 4	10882111	The USA-derived transcriptional coactivator PC2 is a submodule of TRAP/SMCC and acts synergistically with other PCs.

P02400	RLA4_YEAST	60S acidic ribosomal protein P2-beta	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q9VH07	RUVB1_DROME	RuvB-like helicase 1	16087886	Myc interacts genetically with Tip48/Reptin and Tip49/Pontin to control growth and proliferation during Drosophila development.

Q08201	MDR2_RAT	Multidrug resistance protein 2	15159385	Identification of HAX-1 as a protein that binds bile salt export protein and regulates its abundance in the apical membrane of Madin- Darby canine kidney cells.

P43605	ECO1_YEAST	N-acetyltransferase ECO1	18614053	Acetylation of Smc3 by Eco1 is required for S phase sister chromatid cohesion in both human and yeast.

Q96HJ5	MS4A3_HUMAN	Membrane-spanning 4-domains subfamily A member 3	15671017	Binding of HTm4 to cyclin-dependent kinase (Cdk)-associated phosphatase (KAP).Cdk2.cyclin A complex enhances the phosphatase activity of KAP, dissociates cyclin A, and facilitates KAP dephosphorylation of Cdk2.

Q13614	MTMR2_HUMAN	Myotubularin-related protein 2	15998640	The phosphoinositide-3-phosphatase MTMR2 associates with MTMR13, a membrane-associated pseudophosphatase also mutated in type 4B Charcot- Marie-Tooth disease.

P38931	SSN2_YEAST	Mediator of RNA polymerase II transcription subunit 13	15601835	The Saccharomyces cerevisiae Srb8-Srb11 complex functions with the SAGA complex during Gal4-activated transcription.

Q9CQY1	ATG12_MOUSE	Ubiquitin-like protein ATG12	11266458	Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells.

P40071	TMN3_YEAST	Transmembrane 9 superfamily member 3	14562095	Global analysis of protein localization in budding yeast.

P14832	CYPH_YEAST	Peptidyl-prolyl cis-trans isomerase	11711434	The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program.

Q08AH1	ACSM1_HUMAN	Acyl-coenzyme A synthetase ACSM1, mitochondrial	11470804	Molecular identification and characterization of two medium-chain acyl-CoA synthetases, MACS1 and the Sa gene product.

Q9W0G1	PTP61_DROME	Tyrosine-protein phosphatase non-receptor type 61F	9256342	Differential accumulation of DPTP61F alternative transcripts: regulation of a protein tyrosine phosphatase by segmentation genes.

P32802	TMN1_YEAST	Transmembrane 9 superfamily member 1	18178563	Control of cellular physiology by TM9 proteins in yeast and Dictyostelium.

O15553	MEFV_HUMAN	Pyrin	11468188	The familial Mediterranean fever protein, pyrin, associates with microtubules and colocalizes with actin filaments.

O23240	D2HDH_ARATH	D-2-hydroxyglutarate dehydrogenase, mitochondrial	19586914	Two D-2-hydroxy-acid dehydrogenases in Arabidopsis thaliana with catalytic capacities to participate in the last reactions of the methylglyoxal and beta-oxidation pathways.

Q9WTN0	GGPPS_MOUSE	Geranylgeranyl pyrophosphate synthase	10101267	Identification of the GGPS1 genes encoding geranylgeranyl diphosphate synthases from mouse and human.

Q92845	KIFA3_HUMAN	Kinesin-associated protein 3	8900189	SMAP, an Smg GDS-associating protein having arm repeats and phosphorylated by src tyrosine kinase.

P50105	TAF4_YEAST	Transcription initiation factor TFIID subunit 4	12138208	Molecular characterization of Saccharomyces cerevisiae TFIID.

P85974	AGA34_AGAAL	Beta-agarase AgaA34	18071641	Purification and characterization of a novel beta-agarase, AgaA34, from Agarivorans albus YKW-34.

Q66I67	IFT20_DANRE	Intraflagellar transport protein 20 homolog	15182712	Intraflagellar transport genes are essential for differentiation and survival of vertebrate sensory neurons.

P39938	RS26A_YEAST	40S ribosomal protein S26-A	12837249	A panoramic view of yeast noncoding RNA processing.

P16474	GRP78_YEAST	78 kDa glucose-regulated protein homolog	2661018	KAR2, a karyogamy gene, is the yeast homolog of the mammalian BiP/GRP78 gene.

O08934	UNC4_MOUSE	Homeobox protein unc-4 homolog	10804169	The paired homeobox gene Uncx4.1 specifies pedicles, transverse processes and proximal ribs of the vertebral column.

Q62011	PDPN_MOUSE	Podoplanin	10574709	Identification of PA2.26 antigen as a novel cell-surface mucin-type glycoprotein that induces plasma membrane extensions and increased motility in keratinocytes.

P40306	PSB10_HUMAN	Proteasome subunit beta type-10	9551082	Constitutive and interferon-gamma-induced expression of the human proteasome subunit multicatalytic endopeptidase complex-like 1.

Q5AU62	NMRA_EMENI	Nitrogen metabolite repression protein nmrA	15537757	Modulation of the ligand binding properties of the transcription repressor NmrA by GATA-containing DNA and site-directed mutagenesis.

Q9Y7U5	RGF3_SCHPO	Rho1 guanine nucleotide exchange factor 3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O00566	MPP10_HUMAN	U3 small nucleolar ribonucleoprotein protein MPP10	9450966	M phase phosphoprotein 10 is a human U3 small nucleolar ribonucleoprotein component.

Q99PU5	ACBG1_MOUSE	Long-chain-fatty-acid--CoA ligase ACSBG1	14516277	Murine bubblegum orthologue is a microsomal very long-chain acyl-CoA synthetase.

O54960	CAPON_RAT	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein	11867766	Neuronal nitric-oxide synthase localization mediated by a ternary complex with synapsin and CAPON.

P39524	ATC3_YEAST	Probable phospholipid-transporting ATPase DRS2	8247005	DRS1 to DRS7, novel genes required for ribosome assembly and function in Saccharomyces cerevisiae.

Q02457	TBF1_YEAST	Protein TBF1	12200417	General regulatory factors (GRFs) as genome partitioners.

Q96Q83	ALKB3_HUMAN	Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3	16858410	Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage.

P60752	MSBA_ECOLI	Lipid A export ATP-binding/permease protein msbA	12119303	ATPase activity of the MsbA lipid flippase of Escherichia coli.

P0AE06	ACRA_ECOLI	Acriflavine resistance protein A	10920254	Molecular construction of a multidrug exporter system, AcrAB: molecular interaction between AcrA and AcrB, and cleavage of the N- terminal signal sequence of AcrA.

P20788	UCRI_RAT	Cytochrome b-c1 complex subunit Rieske, mitochondrial	2538119	Cloning and sequence analysis of a cDNA encoding the Rieske iron- sulfur protein of rat mitochondrial cytochrome bc1 complex.

Q06810	OPY2_YEAST	Protein OPY2	9383053	Human CPR (cell cycle progression restoration) genes impart a Far- phenotype on yeast cells.

O94334	POF13_SCHPO	F-box protein pof13	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P38703	LAG1_YEAST	Sphingosine N-acyltransferase LAG1	11694577	Lag1p and Lac1p are essential for the acyl-CoA-dependent ceramide synthase reaction in Saccharomyces cerevisae.

Q9H6L5	F134B_HUMAN	Protein FAM134B	19838196	Mutations in FAM134B, encoding a newly identified Golgi protein, cause severe sensory and autonomic neuropathy.

Q9NFU0	FMR1_DROME	Fragile X mental retardation syndrome-related protein 1	12368261	A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins.

Q61136	PRP4B_MOUSE	Serine/threonine-protein kinase PRP4 homolog	9701556	Capturing novel mouse genes encoding chromosomal and other nuclear proteins.

P34288	PAC1_CAEEL	GTPase-activating protein pac-1	8288633	Characterization of a promiscuous GTPase-activating protein that has a bcr-related domain from Caenorhabditis elegans.

Q9P6K4	YLF7_SCHPO	Uncharacterized protein C30C2.07	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P02405	RL44_YEAST	60S ribosomal protein L42	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q62931	GOSR1_RAT	Golgi SNAP receptor complex member 1	8638159	GS28, a 28-kilodalton Golgi SNARE that participates in ER-Golgi transport.

P35372	OPRM_HUMAN	Mu-type opioid receptor	9689128	Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction.

Q12043	TGL5_YEAST	Lipase 5	16135509	Tgl4p and Tgl5p, two triacylglycerol lipases of the yeast Saccharomyces cerevisiae are localized to lipid particles.

O43508	TNF12_HUMAN	Tumor necrosis factor ligand superfamily member 12	9560343	Identification of a ligand for the death-domain-containing receptor Apo3.

O75795	UDB17_HUMAN	UDP-glucuronosyltransferase 2B17	8798464	Isolation and characterization of a novel cDNA encoding a human UDP- glucuronosyltransferase active on C19 steroids.

Q8VCW4	UN93B_MOUSE	Protein unc-93 homolog B1	17452530	The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling.

O75603	GCM2_HUMAN	Chorion-specific transcription factor GCMb	10343099	GCMB, a second human homolog of the fly glide/gcm gene.

O74700	TIM9_YEAST	Mitochondrial import inner membrane translocase subunit TIM9	9889188	Tim9, a new component of the TIM22.54 translocase in mitochondria.

P04430	KV122_HUMAN	Ig kappa chain V-I region BAN	3083240	Polymorphism in a kappa I primary (AL) amyloid protein (BAN).

Q9UT35	GDA1_SCHPO	Guanosine-diphosphatase	14612233	Characterization of gdp1+ as encoding a GDPase in the fission yeast Schizosaccharomyces pombe.

Q8IWQ3	BRSK2_HUMAN	BR serine/threonine-protein kinase 2	14976552	LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1.

P61202	CSN2_MOUSE	COP9 signalosome complex subunit 2	12972599	Disruption of the COP9 signalosome Csn2 subunit in mice causes deficient cell proliferation, accumulation of p53 and cyclin E, and early embryonic death.

Q9NSA1	FGF21_HUMAN	Fibroblast growth factor 21	18829467	C-terminal tail of FGF19 determines its specificity toward Klotho co- receptors.

Q99NH2	PARD3_MOUSE	Partitioning defective 3 homolog	15766746	PAR-3 defines a central subdomain of the cortical actin cap in mouse eggs.

Q9C8G9	AB1C_ARATH	ABC transporter C family member 1	14760709	Large-scale characterization of integral proteins from Arabidopsis vacuolar membrane by two-dimensional liquid chromatography.

Q969P0	IGSF8_HUMAN	Immunoglobulin superfamily member 8	11504738	EWI-2 is a major CD9 and CD81 partner and member of a novel Ig protein subfamily.

Q9UIA9	XPO7_HUMAN	Exportin-7	11071879	Identification of a novel putative Ran-binding protein and its close homologue.

P36051	MCD4_YEAST	GPI ethanolamine phosphate transferase 1	10069808	MCD4 encodes a conserved endoplasmic reticulum membrane protein essential for glycosylphosphatidylinositol anchor synthesis in yeast.

Q0WRC9	SKI17_ARATH	F-box protein SKIP17	12795696	Protein interaction analysis of SCF ubiquitin E3 ligase subunits from Arabidopsis.

Q8RY95	SPL14_ARATH	Squamosa promoter-binding-like protein 14	15703061	Arabidopsis AtSPL14, a plant-specific SBP-domain transcription factor, participates in plant development and sensitivity to fumonisin B1.

Q969Z0	TBRG4_HUMAN	Protein TBRG4	9383053	Human CPR (cell cycle progression restoration) genes impart a Far- phenotype on yeast cells.

O15534	PER1_HUMAN	Period circadian protein homolog 1	9323128	Rigui, a putative mammalian ortholog of the Drosophila period gene.

Q9H3R5	CENPH_HUMAN	Centromere protein H	15713649	The functional region of CENP-H interacts with the Nuf2 complex that localizes to centromere during mitosis.

O94261	FTA3_SCHPO	Kinetochore protein fta3	16079914	Molecular analysis of kinetochore architecture in fission yeast.

P36860	RALB_RAT	Ras-related protein Ral-B	7687439	Isolation of cDNA clones and tissue expression of rat ral A and ral B GTP-binding proteins.

Q9HBU9	POPD2_HUMAN	Popeye domain-containing protein 2	10882522	Isolation and characterization of the novel popeye gene family expressed in skeletal muscle and heart.

O43172	PRP4_HUMAN	U4/U6 small nuclear ribonucleoprotein Prp4	9328476	Identification and characterization of human genes encoding Hprp3p and Hprp4p, interacting components of the spliceosome.

O14230	FPPS_SCHPO	Farnesyl pyrophosphate synthase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UKI8	TLK1_HUMAN	Serine/threonine-protein kinase tousled-like 1	10523312	Mammalian homologues of the plant tousled gene code for cell-cycle- regulated kinases with maximal activities linked to ongoing DNA replication.

P32010	DRRA_STRPE	Daunorubicin/doxorubicin resistance ATP-binding protein drrA	9006006	Expression and characterization of DrrA and DrrB proteins of Streptomyces peucetius in Escherichia coli: DrrA is an ATP binding protein.

O43070	NBS1_SCHPO	DNA repair and telomere maintenance protein nbs1	12944482	The fission yeast Rad32 (Mre11)-Rad50-Nbs1 complex is required for the S-phase DNA damage checkpoint.

P14091	CATE_HUMAN	Cathepsin E	7983070	Subcellular localization and targeting of cathepsin E.

Q16566	KCC4_HUMAN	Calcium/calmodulin-dependent protein kinase type IV	8089075	cDNA cloning and expression of human calmodulin-dependent protein kinase IV.

Q6F2E7	SOX9_XENTR	Transcription factor Sox-9	18692165	Skeletogenesis in Xenopus tropicalis: characteristic bone development in an anuran amphibian.

Q39102	FTSH1_ARATH	ATP-dependent zinc metalloprotease FTSH 1, chloroplastic	14630971	Coordinated regulation and complex formation of yellow variegated1 and yellow variegated2, chloroplastic FtsH metalloproteases involved in the repair cycle of photosystem II in Arabidopsis thylakoid membranes.

Q68KI4	NHX1_ARATH	Sodium/hydrogen exchanger 1	10455050	Salt tolerance conferred by overexpression of a vacuolar Na(+)/H(+) antiport in Arabidopsis.

Q59E55	NAB_DROME	NGFI-A-binding protein homolog	17428824	Nab controls the activity of the zinc-finger transcription factors Squeeze and Rotund in Drosophila development.

P52868	CWC23_YEAST	Pre-mRNA-splicing factor CWC23	11884590	Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

Q9Y6V0	PCLO_HUMAN	Protein piccolo	10508862	Aczonin, a 550-kd putative scaffolding protein of presynaptic active zones, shares homology regions with rim and bassoon and binds profilin.

Q02159	UBC7_YEAST	Ubiquitin-conjugating enzyme E2 7	9388185	Role of Cue1p in ubiquitination and degradation at the ER surface.

Q921W0	CHM1A_MOUSE	Charged multivesicular body protein 1a	11559747	CHMP1 is a novel nuclear matrix protein affecting chromatin structure and cell-cycle progression.

Q42371	ERECT_ARATH	LRR receptor-like serine/threonine-protein kinase ERECTA	12874130	Novel as1 and as2 defects in leaf adaxial-abaxial polarity reveal the requirement for ASYMMETRIC LEAVES1 and 2 and ERECTA functions in specifying leaf adaxial identity.

Q86A97	TSSC1_DICDI	Protein tssc1 homolog	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q7JW27	WASH1_DROME	WAS protein family homolog 1	18159949	Human subtelomeric WASH genes encode a new subclass of the WASP family.

Q08749	TIM18_YEAST	Mitochondrial import inner membrane translocase subunit TIM18	10648604	Tim18p, a new subunit of the TIM22 complex that mediates insertion of imported proteins into the yeast mitochondrial inner membrane.

P35569	IRS1_MOUSE	Insulin receptor substrate 1	11018022	Cloning and characterization of PHIP, a novel insulin receptor substrate-1 pleckstrin homology domain interacting protein.

Q9UKB1	FBW1B_HUMAN	F-box/WD repeat-containing protein 11	10531035	Identification of a family of human F-box proteins.

Q96E93	KLRG1_HUMAN	Killer cell lectin-like receptor subfamily G member 1	9842918	MAFA-L, an ITIM-containing receptor encoded by the human NK cell gene complex and expressed by basophils and NK cells.

Q9WU38	SCNNB_MOUSE	Amiloride-sensitive sodium channel subunit beta	10409305	Cloning and functional expression of the mouse epithelial sodium channel.

P97334	NKX23_MOUSE	Homeobox protein Nkx-2.3	10790368	NKX2.3 is required for MAdCAM-1 expression and homing of lymphocytes in spleen and mucosa-associated lymphoid tissue.

O22768	UNE12_ARATH	Transcription factor UNE12	15634699	Genetic and molecular identification of genes required for female gametophyte development and function in Arabidopsis.

Q8WUD6	CHPT1_HUMAN	Cholinephosphotransferase 1	10893425	Cloning, genomic organization, and characterization of a human cholinephosphotransferase.

P34218	SAS3_YEAST	Histone acetyltransferase SAS3	17157260	Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs.

P12504	VIF_HV1N5	Virion infectivity factor	14528301	HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation.

Q92796	DLG3_HUMAN	Disks large homolog 3	9188857	Cloning and characterization of NE-dlg: a novel human homolog of the Drosophila discs large (dlg) tumor suppressor protein interacts with the APC protein.

O14828	SCAM3_HUMAN	Secretory carrier-associated membrane protein 3	9378760	Three mammalian SCAMPs (secretory carrier membrane proteins) are highly related products of distinct genes having similar subcellular distributions.

P12945	NAT1_YEAST	N-terminal acetyltransferase A complex subunit NAT1	14517307	The yeast N(alpha)-acetyltransferase NatA is quantitatively anchored to the ribosome and interacts with nascent polypeptides.

P47987	PLLP_RAT	Plasmolipin	7929173	Molecular cloning of plasmolipin. Characterization of a novel proteolipid restricted to brain and kidney.

Q9BSQ5	CCM2_HUMAN	Malcavernin	14740320	Mutations within the MGC4607 gene cause cerebral cavernous malformations.

O74742	FOLE_SCHPO	Probable folylpolyglutamate synthase	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

Q16773	KAT1_HUMAN	Kynurenine--oxoglutarate transaminase 1	19338303	Structural insight into the inhibition of human kynurenine aminotransferase I/glutamine transaminase K.

Q96FV9	THOC1_HUMAN	THO complex subunit 1	15833825	Linking transcriptional elongation and messenger RNA export to metastatic breast cancers.

P43320	CRBB2_HUMAN	Beta-crystallin B2	8224918	Sequence of the human lens beta B2-crystallin-encoding cDNA.

P16621	LAR_DROME	Tyrosine-protein phosphatase Lar	8598047	The transmembrane tyrosine phosphatase DLAR controls motor axon guidance in Drosophila.

Q9FH02	FTSH5_ARATH	ATP-dependent zinc metalloprotease FTSH 5, chloroplastic	14630971	Coordinated regulation and complex formation of yellow variegated1 and yellow variegated2, chloroplastic FtsH metalloproteases involved in the repair cycle of photosystem II in Arabidopsis thylakoid membranes.

P30987	TA2R_MOUSE	Thromboxane A2 receptor	1375456	Mouse thromboxane A2 receptor: cDNA cloning, expression and northern blot analysis.

Q16186	ADRM1_HUMAN	Proteasomal ubiquitin receptor ADRM1	8033103	Molecular cloning and characterization of the complementary DNA of an M(r) 110,000 antigen expressed by human gastric carcinoma cells and upregulated by gamma-interferon.

O15131	IMA5_HUMAN	Importin subunit alpha-6	9395085	Cloning of two novel human importin-alpha subunits and analysis of the expression pattern of the importin-alpha protein family.

P49621	DGKB_RAT	Diacylglycerol kinase beta	7689223	Molecular cloning and expression of a 90-kDa diacylglycerol kinase that predominantly localizes in neurons.

P24871	CG24_YEAST	G2/mitotic-specific cyclin-4	1387566	Characterization of four B-type cyclin genes of the budding yeast Saccharomyces cerevisiae.

Q61521	EREG_MOUSE	Proepiregulin	7706296	Epiregulin, a novel epidermal growth factor with mitogenic activity for rat primary hepatocytes.

Q8I7F8	ODR4_CAEEL	Odorant response abnormal protein 4	9590179	Odorant receptor localization to olfactory cilia is mediated by ODR- 4, a novel membrane-associated protein.

Q84UV8	NEC3_NICLS	Bifunctional monodehydroascorbate reductase and carbonic anhydrase nectarin-3	15284496	Tobacco nectarin III is a bifunctional enzyme with monodehydroascorbate reductase and carbonic anhydrase activities.

P24347	MMP11_HUMAN	Stromelysin-3	7746327	Furin-dependent intracellular activation of the human stromelysin-3 zymogen.

Q12701	KSG1_SCHPO	Serine/threonine-protein kinase ksg1	10071224	A Schizosaccharomyces pombe gene, ksg1, that shows structural homology to the human phosphoinositide-dependent protein kinase PDK1, is essential for growth, mating and sporulation.

O43464	HTRA2_HUMAN	Serine protease HTRA2, mitochondrial	10971580	Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress response.

Q9UU85	PPK38_SCHPO	Protein kinase domain-containing protein ppk38	15821139	Systematic deletion analysis of fission yeast protein kinases.

Q01802	AATM_YEAST	Aspartate aminotransferase, mitochondrial	1482685	AAT1, a gene encoding a mitochondrial aspartate aminotransferase in Saccharomyces cerevisiae.

Q14790	CASP8_HUMAN	Caspase-8	11917123	The procaspase-8 isoform, procaspase-8L, recruited to the BAP31 complex at the endoplasmic reticulum.

P36394	SRY_RAT	Sex-determining region Y protein	16488877	Direct regulation of adult brain function by the male-specific factor SRY.

P0C2B7	RM52_BOVIN	39S ribosomal protein L52, mitochondrial	11551941	The large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present.

Q6Q783	SV422_MOUSE	Histone-lysine N-methyltransferase SUV420H2	15145825	A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin.

P46520	EMP1_ORYSJ	Embryonic abundant protein 1	7599651	Regulation of the Osem gene by abscisic acid and the transcriptional activator VP1: analysis of cis-acting promoter elements required for regulation by abscisic acid and VP1.

Q9NRR6	INP5E_HUMAN	72 kDa inositol polyphosphate 5-phosphatase	10764818	The isolation and characterization of a cDNA encoding phospholipid- specific inositol polyphosphate 5-phosphatase.

P25357	SNT1_YEAST	Probable DNA-binding protein SNT1	11711434	The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program.

Q9C100	PMT2_SCHPO	Dolichyl-phosphate-mannose--protein mannosyltransferase 2	15809069	Characterization of O-mannosyltransferase family in Schizosaccharomyces pombe.

Q9ULT8	HECD1_HUMAN	E3 ubiquitin-protein ligase HECTD1	12421765	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

Q58G47	TIF6A_ARATH	Protein TIFY 6A	20360743	NINJA connects the co-repressor TOPLESS to jasmonate signalling.

P34167	IF4B_YEAST	Eukaryotic translation initiation factor 4B	8404866	A new yeast translation initiation factor suppresses a mutation in the eIF-4A RNA helicase.

Q9FJP9	DHSB3_ARATH	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit 3, mitochondrial	11442063	Three different genes encode the iron-sulphur subunit of succinate dehydrogenase in Arabidopsis thaliana.

Q64121	PRLHR_RAT	Prolactin-releasing peptide receptor	7733930	Sequence and tissue distribution of a candidate G-coupled receptor cloned from rat hypothalamus.

P42229	STA5A_HUMAN	Signal transducer and activator of transcription 5A	7719937	Identification and purification of human Stat proteins activated in response to interleukin-2.

Q15700	DLG2_HUMAN	Disks large homolog 2	15304517	An alternatively spliced isoform of PSD-93/chapsyn 110 binds to the inwardly rectifying potassium channel, Kir2.1.

P16234	PGFRA_HUMAN	Alpha-type platelet-derived growth factor receptor	2536956	Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes.

P02730	B3AT_HUMAN	Band 3 anion transport protein	1527044	A structural study of the membrane domain of band 3 by tryptic digestion. Conformational change of band 3 in situ induced by alkali treatment.

Q78E65	JDP2_RAT	Jun dimerization protein 2	9154808	Isolation of an AP-1 repressor by a novel method for detecting protein-protein interactions.

P42892	ECE1_HUMAN	Endothelin-converting enzyme 1	7864876	Cloning and functional expression of human endothelin-converting enzyme cDNA.

Q9SXE1	GSOX3_ARATH	Flavin-containing monooxygenase FMO GS-OX3	18799661	Subclade of flavin-monooxygenases involved in aliphatic glucosinolate biosynthesis.

P78504	JAG1_HUMAN	Protein jagged-1	10329626	Rel/NF-kappaB can trigger the Notch signaling pathway by inducing the expression of Jagged1, a ligand for Notch receptors.

O95232	LC7L3_HUMAN	Luc7-like protein 3	18663000	Novel splicing factor RBM25 modulates Bcl-x pre-mRNA 5' splice site selection.

Q9VVR2	BORA_DROME	Protein aurora borealis	16890155	Mitotic activation of the kinase Aurora-A requires its binding partner Bora.

O46084	PGAM5_DROME	Serine/threonine-protein phosphatase Pgam5, mitochondrial	19590015	Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1.

O74822	YBJB_SCHPO	Zinc-type alcohol dehydrogenase-like protein C337.11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q80WB5	NTAQ1_MOUSE	Protein N-terminal glutamine amidohydrolase	19560421	Glutamine-specific N-terminal amidase, a component of the N-end rule pathway.

Q9V3K3	RUVB2_DROME	RuvB-like helicase 2	16618800	A Polycomb group protein complex with sequence-specific DNA-binding and selective methyl-lysine-binding activities.

Q62120	JAK2_MOUSE	Tyrosine-protein kinase JAK2	9590173	Jak2 is essential for signaling through a variety of cytokine receptors.

O89110	CASP8_MOUSE	Caspase-8	18455983	TIPE2, a negative regulator of innate and adaptive immunity that maintains immune homeostasis.

P70040	FEN1A_XENLA	Flap endonuclease 1-A	9535864	Involvement of flap endonuclease 1 in base excision DNA repair.

Q3EDG5	TPST_ARATH	Protein-tyrosine sulfotransferase	19666544	Identification of tyrosylprotein sulfotransferase in Arabidopsis.

P52741	ZN134_HUMAN	Zinc finger protein 134	7557990	Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders.

O94370	YG04_SCHPO	Uncharacterized mitochondrial carrier C1604.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q0WML0	AB27B_ARATH	ABC transporter B family member 27	16618929	Mapping the Arabidopsis organelle proteome.

O14514	BAI1_HUMAN	Brain-specific angiogenesis inhibitor 1	9647739	Cloning and characterization of BAI-associated protein 1: a PDZ domain-containing protein that interacts with BAI1.

Q8R1W2	GSG1_MOUSE	Germ cell-specific gene 1 protein	18325338	Germ cell-specific gene 1 targets testis-specific poly(A) polymerase to the endoplasmic reticulum through protein-protein interactions.

Q05827	HOR7_YEAST	Protein HOR7	7500933	Cloning and characterization of seven cDNAs for hyperosmolarity- responsive (HOR) genes of Saccharomyces cerevisiae.

Q9ESC1	ELTD1_RAT	EGF, latrophilin and seven transmembrane domain-containing protein 1	11050079	ETL, a novel seven-transmembrane receptor that is developmentally regulated in the heart.

P40240	CD9_MOUSE	CD9 antigen	14715942	Tetraspanin protein CD9 is a novel paranodal component regulating paranodal junctional formation.

P36523	RM15_YEAST	54S ribosomal protein L15, mitochondrial	12392552	Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components.

Q5U4X3	MEI3A_XENLA	Homeobox protein meis3-A	15196951	The Meis3 protein and retinoid signaling interact to pattern the Xenopus hindbrain.

Q9NRM6	I17RB_HUMAN	Interleukin-17 receptor B	10815801	Evi27 encodes a novel membrane protein with homology to the IL17 receptor.

P04201	MAS_HUMAN	Proto-oncogene Mas	3419518	The mas oncogene encodes an angiotensin receptor.

Q9UU88	KAD6_SCHPO	Putative adenylate kinase fap7	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O43597	SPY2_HUMAN	Protein sprouty homolog 2	9458049	Sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways.

Q9SV87	BRN2_ARATH	Protein BEARSKIN1	20197506	SOMBRERO, BEARSKIN1, and BEARSKIN2 regulate root cap maturation in Arabidopsis.

Q6J163	5NG4_PINTA	Auxin-induced protein 5NG4	14722770	An auxin-inducible gene from loblolly pine (Pinus taeda L.) is differentially expressed in mature and juvenile-phase shoots and encodes a putative transmembrane protein.

Q9UTL9	YIV5_SCHPO	Uncharacterized ATP-dependent helicase C144.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P36080	RRP14_YEAST	Ribosomal RNA-processing protein 14	17272295	Yeast Rrp14p is required for ribosomal subunit synthesis and for correct positioning of the mitotic spindle during mitosis.

P02768	ALBU_HUMAN	Serum albumin	9731778	Crystal structure of human serum albumin complexed with fatty acid reveals an asymmetric distribution of binding sites.

Q15013	MD2BP_HUMAN	MAD2L1-binding protein	12456649	Identification of a MAD2-binding protein, CMT2, and its role in mitosis.

Q968Y9	INSR_CAEEL	Insulin-like receptor	9790527	Cell nonautonomy of C. elegans daf-2 function in the regulation of diapause and life span.

P53215	THG1_YEAST	tRNA(His) guanylyltransferase	14633974	tRNAHis maturation: an essential yeast protein catalyzes addition of a guanine nucleotide to the 5' end of tRNAHis.

O95716	RAB3D_HUMAN	Ras-related protein Rab-3D	10023084	Molecular cloning of cDNA encoding human Rab3D whose expression is upregulated with myeloid differentiation.

Q5I0E9	S47A1_RAT	Multidrug and toxin extrusion protein 1	17047166	Oppositely directed H+ gradient functions as a driving force of rat H+/organic cation antiporter MATE1.

P22791	HMCS2_RAT	Hydroxymethylglutaryl-CoA synthase, mitochondrial	8097464	The rat mitochondrial 3-hydroxy-3-methylglutaryl-coenzyme-A-synthase gene contains elements that mediate its multihormonal regulation and tissue specificity.

Q92973	TNPO1_HUMAN	Transportin-1	9144189	Karyopherin beta2 mediates nuclear import of a mRNA binding protein.

Q86Z02	HIPK1_HUMAN	Homeodomain-interacting protein kinase 1	12529400	Homeodomain-interacting protein kinase 1 modulates Daxx localization, phosphorylation, and transcriptional activity.

Q9H251	CAD23_HUMAN	Cadherin-23	11138009	Mutation of CDH23, encoding a new member of the cadherin gene family, causes Usher syndrome type 1D.

P02533	K1C14_HUMAN	Keratin, type I cytoskeletal 14	11684708	Keratin attenuates tumor necrosis factor-induced cytotoxicity through association with TRADD.

Q9JLV5	CUL3_MOUSE	Cullin-3	10500095	Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells.

Q9M0V3	DDB1A_ARATH	DNA damage-binding protein 1a	18223036	Characterization of Arabidopsis and rice DWD proteins and their roles as substrate receptors for CUL4-RING E3 ubiquitin ligases.

Q9CA40	NUDT1_ARATH	Nudix hydrolase 1	15611104	A nudix enzyme removes pyrophosphate from dihydroneopterin triphosphate in the folate synthesis pathway of bacteria and plants.

B9DFG3	ISE2_ARATH	DEAD-box ATP-dependent RNA helicase ISE2, chloroplastic	17601829	INCREASED SIZE EXCLUSION LIMIT 2 encodes a putative DEVH box RNA helicase involved in plasmodesmata function during Arabidopsis embryogenesis.

P08195	4F2_HUMAN	4F2 cell-surface antigen heavy chain	10903140	The heterodimeric amino acid transporter 4F2hc/y+LAT2 mediates arginine efflux in exchange with glutamine.

P06169	PDC1_YEAST	Pyruvate decarboxylase isozyme 1	12499363	The catabolism of amino acids to long chain and complex alcohols in Saccharomyces cerevisiae.

P43254	COP1_ARATH	E3 ubiquitin-protein ligase COP1	11461903	The phytochrome A-specific signaling intermediate SPA1 interacts directly with COP1, a constitutive repressor of light signaling in Arabidopsis.

Q9CR25	DPH2_MOUSE	Diphthamide biosynthesis protein 2	15485916	Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2.

P40169	YNT4_YEAST	Uncharacterized plasma membrane protein YNL194C	11784867	The Sur7p family defines novel cortical domains in Saccharomyces cerevisiae, affects sphingolipid metabolism, and is involved in sporulation.

Q99278	MED11_YEAST	Mediator of RNA polymerase II transcription subunit 11	16885025	Head module control of mediator interactions.

Q93WC9	IPT3_ARATH	Adenylate isopentenyltransferase 3, chloroplastic	18184738	Farnesylation directs AtIPT3 subcellular localization and modulates cytokinin biosynthesis in Arabidopsis.

Q9XZL8	SRA_DROME	Protein sarah	16860743	The calcineurin regulator sra plays an essential role in female meiosis in Drosophila.

P12385	ERF1_YEAST	Eukaryotic peptide chain release factor subunit 1	16809762	Tpa1p is part of an mRNP complex that influences translation termination, mRNA deadenylation, and mRNA turnover in Saccharomyces cerevisiae.

P00492	HPRT_HUMAN	Hypoxanthine-guanine phosphoribosyltransferase	10360366	The 2.0 A structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with a transition-state analog inhibitor.

O60093	SRR1L_SCHPO	SRR1-like protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UUK4	YLO2_SCHPO	Uncharacterized protein C1952.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q98SP8	EPABA_XENLA	Embryonic polyadenylate-binding protein A	15713657	Embryonic poly(A)-binding protein stimulates translation in germ cells.

P32746	PYRD_ARATH	Dihydroorotate dehydrogenase, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q9URY5	FHP_SCHPO	Flavohemoprotein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P15407	FOSL1_HUMAN	Fos-related antigen 1	2107490	Isolation of human fos-related genes and their expression during monocyte-macrophage differentiation.

P54763	EPHB2_MOUSE	Ephrin type-B receptor 2	15107857	Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling.

Q91ZD4	VANG2_MOUSE	Vang-like protein 2	11709546	Severe neural tube defects in the loop-tail mouse result from mutation of Lpp1, a novel gene involved in floor plate specification.

P79960	APJA_XENLA	Apelin receptor A	16876154	Xapelin and Xmsr are required for cardiovascular development in Xenopus laevis.

P31382	PMT2_YEAST	Dolichyl-phosphate-mannose--protein mannosyltransferase 2	7852348	Protein O-glycosylation in yeast. The PMT2 gene specifies a second protein O-mannosyltransferase that functions in addition to the PMT1- encoded activity.

Q9S7Z8	PIN3_ARATH	Auxin efflux carrier component 3	11845211	Lateral relocation of auxin efflux regulator PIN3 mediates tropism in Arabidopsis.

P23083	HV103_HUMAN	Ig heavy chain V-I region V35	2841108	Dispersed localization of D segments in the human immunoglobulin heavy-chain locus.

P35208	SPT10_YEAST	Protein SPT10	8264536	Isolation and characterization of the SUD1 gene, which encodes a global repressor of core promoter activity in Saccharomyces cerevisiae.

P47160	ENT3_YEAST	Epsin-3	15107463	Ent5p is required with Ent3p and Vps27p for ubiquitin-dependent protein sorting into the multivesicular body.

Q9Y6M4	KC1G3_HUMAN	Casein kinase I isoform gamma-3	9925945	Cloning and chromosome mapping of the human casein kinase I gamma3 gene (CSNK1G3).

Q9P324	YI78_SCHPO	Uncharacterized oxidoreductase C977.08/C1348.09	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O13637	SEC31_SCHPO	Protein transport protein sec31	11839792	Three proteins required for early steps in the protein secretory pathway also affect nuclear envelope structure and cell cycle progression in fission yeast.

P06242	KIN28_YEAST	Serine/threonine-protein kinase KIN28	11839796	Kin28 is found within TFIIH and a Kin28-Ccl1-Tfb3 trimer complex with differential sensitivities to T-loop phosphorylation.

P51572	BAP31_HUMAN	B-cell receptor-associated protein 31	11917123	The procaspase-8 isoform, procaspase-8L, recruited to the BAP31 complex at the endoplasmic reticulum.

P32786	RRN6_YEAST	RNA polymerase I-specific transcription initiation factor RRN6	7958901	RRN6 and RRN7 encode subunits of a multiprotein complex essential for the initiation of rDNA transcription by RNA polymerase I in Saccharomyces cerevisiae.

Q9QZA2	PDC6I_RAT	Programmed cell death 6-interacting protein	10858458	The glioma-associated protein SETA interacts with AIP1/Alix and ALG-2 and modulates apoptosis in astrocytes.

Q23023	UNC51_CAEEL	Serine/threonine-protein kinase unc-51	7958904	Caenorhabditis elegans unc-51 gene required for axonal elongation encodes a novel serine/threonine kinase.

O04921	HEMH2_ARATH	Ferrochelatase-2, chloroplastic	9753778	Two different genes encode ferrochelatase in Arabidopsis: mapping, expression and subcellular targeting of the precursor proteins.

Q6AYE8	ARTN_RAT	Artemin	10719212	Expression of the GDNF family members and their receptors in the mature rat cochlea.

O75325	LRRN2_HUMAN	Leucine-rich repeat neuronal protein 2	9662332	GAC1, a new member of the leucine-rich repeat superfamily on chromosome band 1q32.1, is amplified and overexpressed in malignant gliomas.

Q9ER62	TNR22_MOUSE	Tumor necrosis factor receptor superfamily member 22	12466268	Identification of a new murine tumor necrosis factor receptor locus that contains two novel murine receptors for tumor necrosis factor- related apoptosis-inducing ligand (TRAIL).

O13938	YEP4_SCHPO	UPF0658 Golgi apparatus membrane protein C23H3.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P52505	ACPM_BOVIN	Acyl carrier protein, mitochondrial	1907568	Presence of an acyl carrier protein in NADH:ubiquinone oxidoreductase from bovine heart mitochondria.

P62330	ARF6_HUMAN	ADP-ribosylation factor 6	16148947	Rab11-FIP3 and FIP4 interact with Arf6 and the exocyst to control membrane traffic in cytokinesis.

P83483	ATPBM_ARATH	ATP synthase subunit beta-1, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P32837	UGA4_YEAST	GABA-specific permease	14985124	Uptake of GABA and putrescine by UGA4 on the vacuolar membrane in Saccharomyces cerevisiae.

Q43127	GLNA2_ARATH	Glutamine synthetase, chloroplastic/mitochondrial	10482686	Carbon and amino acids reciprocally modulate the expression of glutamine synthetase in Arabidopsis.

P53665	ACPM_ARATH	Acyl carrier protein, mitochondrial	8016262	The characterization of a mitochondrial acyl carrier protein isoform isolated from Arabidopsis thaliana.

Q9NKX1	ENPL_DICDI	Endoplasmin homolog	15652353	Changes in spatial and temporal localization of Dictyostelium homologues of TRAP1 and GRP94 revealed by immunoelectron microscopy.

O09110	MP2K3_MOUSE	Dual specificity mitogen-activated protein kinase kinase 3	8900184	Purification and identification of a major activator for p38 from osmotically shocked cells: activation of mitogen-activated protein kinase kinase 6 by osmotic shock, tumor necrosis factor-alpha, and H2O2.

Q60974	NCOR1_MOUSE	Nuclear receptor corepressor 1	8961273	Two receptor interacting domains in the nuclear hormone receptor corepressor RIP13/N-CoR.

Q9P2D1	CHD7_HUMAN	Chromodomain-helicase-DNA-binding protein 7	15300250	Mutations in a new member of the chromodomain gene family cause CHARGE syndrome.

P54709	AT1B3_HUMAN	Sodium/potassium-transporting ATPase subunit beta-3	8798450	Identification of the mammalian Na,K-ATPase 3 subunit.

O14757	CHK1_HUMAN	Serine/threonine-protein kinase Chk1	9382850	Atm-dependent interactions of a mammalian chk1 homolog with meiotic chromosomes.

P36877	2ABB_RAT	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform	15923182	Unfolding-resistant translocase targeting: a novel mechanism for outer mitochondrial membrane localization exemplified by the Bbeta2 regulatory subunit of protein phosphatase 2A.

P78556	CCL20_HUMAN	C-C motif chemokine 20	9038201	Molecular cloning of a novel human CC chemokine liver and activation- regulated chemokine (LARC) expressed in liver. Chemotactic activity for lymphocytes and gene localization on chromosome 2.

O13298	PHD1_SCHPO	Histone deacetylase phd1	9628926	Genetic characterisation of hda1+, a putative fission yeast histone deacetylase gene.

P93050	RKF3_ARATH	Probable LRR receptor-like serine/threonine-protein kinase RKF3	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q9EP79	V1R52_MOUSE	Vomeronasal type-1 receptor 52	11116090	Sequence diversity and genomic organization of vomeronasal receptor genes in the mouse.

Q99988	GDF15_HUMAN	Growth/differentiation factor 15	9348093	Human cDNA encoding a novel TGF-beta superfamily protein highly expressed in placenta.

Q15014	MO4L2_HUMAN	Mortality factor 4-like protein 2	14506250	MRGX is a novel transcriptional regulator that exhibits activation or repression of the B-myb promoter in a cell type-dependent manner.

P32944	SWE1_YEAST	Mitosis inhibitor protein kinase SWE1	8253069	Properties of Saccharomyces cerevisiae wee1 and its differential regulation of p34CDC28 in response to G1 and G2 cyclins.

P43699	NKX21_HUMAN	Homeobox protein Nkx-2.1	7713914	Gene structure and expression of human thyroid transcription factor-1 in respiratory epithelial cells.

Q04891	SOX13_MOUSE	Transcription factor SOX-13	9421502	High expression of the HMG box factor sox-13 in arterial walls during embryonic development.

Q9ERS5	PKHA2_MOUSE	Pleckstrin homology domain-containing family A member 2	14516276	Interaction of the protein tyrosine phosphatase PTPL1 with the PtdIns(3,4)P2-binding adaptor protein TAPP1.

Q9US26	FTA2_SCHPO	Kinetochore protein fta2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9BY44	EIF2A_HUMAN	Eukaryotic translation initiation factor 2A	12133843	Characterization of mammalian eIF2A and identification of the yeast homolog.

O61613	NMT_DROME	Glycylpeptide N-tetradecanoyltransferase	9044045	Sequence and expression of Drosophila myristoyl-CoA: protein N- myristoyl transferase: evidence for proteolytic processing and membrane localisation.

O95299	NDUAA_HUMAN	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial	9878551	cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed.

P49247	RPIA_HUMAN	Ribose-5-phosphate isomerase	7758956	The ribose 5-phosphate isomerase-encoding gene is located immediately downstream from that encoding murine immunoglobulin kappa.

O65258	BAM2_ARATH	Beta-amylase 2, chloroplastic	18390594	Beta-AMYLASE4, a noncatalytic protein required for starch breakdown, acts upstream of three active beta-amylases in Arabidopsis chloroplasts.

O60882	MMP20_HUMAN	Matrix metalloproteinase-20	9398237	Identification and structural and functional characterization of human enamelysin (MMP-20).

P51812	KS6A3_HUMAN	Ribosomal protein S6 kinase alpha-3	8955270	Mutations in the kinase Rsk-2 associated with Coffin-Lowry syndrome.

P0AC47	FRDB_ECOLI	Fumarate reductase iron-sulfur subunit	10373108	Structure of the Escherichia coli fumarate reductase respiratory complex.

Q09123	SCRK_FUSMR	Fructokinase	1533618	Sucrose fermentation by Fusobacterium mortiferum ATCC 25557: transport, catabolism, and products.

O96033	MOC2A_HUMAN	Molybdopterin synthase sulfur carrier subunit	10053004	Human molybdopterin synthase gene: genomic structure and mutations in molybdenum cofactor deficiency type B.

Q99NH3	R3GEF_RAT	Guanine nucleotide exchange factor for Rab-3A	11516400	GRAB: a physiologic guanine nucleotide exchange factor for Rab3A, which interacts with inositol hexakisphosphate kinase.

Q6VVW9	CP2R1_MOUSE	Vitamin D 25-hydroxylase	12867411	De-orphanization of cytochrome P450 2R1: a microsomal vitamin D 25- hydroxylase.

P0A8H8	YACG_ECOLI	UPF0243 zinc-binding protein yacG	12211008	NMR structure of the Escherichia coli protein YacG: a novel sequence motif in the zinc-finger family of proteins.

Q8BLE7	VGLU2_MOUSE	Vesicular glutamate transporter 2	11432869	Molecular and functional analysis of a novel neuronal vesicular glutamate transporter.

P17480	UBF1_HUMAN	Nucleolar transcription factor 1	2330041	Nucleolar transcription factor hUBF contains a DNA-binding motif with homology to HMG proteins.

Q93646	SNT1_CAEEL	Syntrophin-1	14499607	The stn-1 syntrophin gene of C.elegans is functionally related to dystrophin and dystrobrevin.

Q15750	TAB1_HUMAN	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1	11460167	TAK1 is a ubiquitin-dependent kinase of MKK and IKK.

Q63623	RBM16_RAT	Putative RNA-binding protein 16	8692929	The C-terminal domain of the largest subunit of RNA polymerase II interacts with a novel set of serine/arginine-rich proteins.

Q9M651	RAGP2_ARATH	RAN GTPase-activating protein 2	12061901	Plant RanGAPs are localized at the nuclear envelope in interphase and associated with microtubules in mitotic cells.

Q99252	ECM3_YEAST	Protein ECM3	9335584	Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae.

Q801X7	AJL1_ANGJA	Galactose-binding lectin l-1	14698218	Characteristics and primary structure of a galectin in the skin mucus of the Japanese eel, Anguilla japonica.

P25940	CO5A3_HUMAN	Collagen alpha-3(V) chain	1571108	Isolation of the alpha 3-chain of human type V collagen and characterization by partial sequencing.

Q12906	ILF3_HUMAN	Interleukin enhancer-binding factor 3	7519613	Cloning and expression of cyclosporin A- and FK506-sensitive nuclear factor of activated T-cells: NF45 and NF90.

Q3URR7	ZSC10_MOUSE	Zinc finger and SCAN domain-containing protein 10	19740739	Zfp206, Oct4, and Sox2 are integrated components of a transcriptional regulatory network in embryonic stem cells.

Q9USJ8	CTK3_SCHPO	CTD kinase subunit gamma	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12024	YTM1_YEAST	Ribosome biogenesis protein YTM1	16287855	Ytm1, Nop7, and Erb1 form a complex necessary for maturation of yeast 66S preribosomes.

Q3MKQ1	BEX2_RAT	Protein BEX2	15958283	Characterization of the Bex gene family in humans, mice, and rats.

P21333	FLNA_HUMAN	Filamin-A	18322202	Filamin A stabilizes FcgammaRI surface expression and prevents its lysosomal routing.

P35548	MSX2_HUMAN	Homeobox protein MSX-2	12145306	Regulation of osteocalcin gene expression by a novel Ku antigen transcription factor complex.

P25604	STP22_YEAST	Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease	15044434	Structural insights into endosomal sorting complex required for transport (ESCRT-I) recognition of ubiquitinated proteins.

Q9SRX9	BAH1_ARATH	E3 ubiquitin-protein ligase BAH1	18753285	BAH1/NLA, a RING-type ubiquitin E3 ligase, regulates the accumulation of salicylic acid and immune responses to pseudomonas syringae DC3000.

Q76EJ0	YABDL_ORYSJ	Protein DROOPING LEAF	12506001	SUPERWOMAN1 and DROOPING LEAF genes control floral organ identity in rice.

Q9VWE0	DOME_DROME	Cytokine receptor	12403714	The Drosophila cytokine receptor Domeless controls border cell migration and epithelial polarization during oogenesis.

P23743	DGKA_HUMAN	Diacylglycerol kinase alpha	2175712	Purification, cDNA-cloning and expression of human diacylglycerol kinase.

Q21952	NUF2_CAEEL	Kinetochore protein Nuf2 homolog	14522947	KNL-1 directs assembly of the microtubule-binding interface of the kinetochore in C. elegans.

Q9NRH3	TBG2_HUMAN	Tubulin gamma-2 chain	10903841	The gamma-tubulin gene family in humans.

P14682	UBC3_YEAST	Ubiquitin-conjugating enzyme E2-34 kDa	9499404	Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box protein complexes that regulate cell division and methionine biosynthesis in yeast.

Q9R237	JIP1_RAT	C-Jun-amino-terminal kinase-interacting protein 1	10098834	Molecular cloning of multiple splicing variants of JIP-1 preferentially expressed in brain.

Q12443	RTN2_YEAST	Reticulon-like protein 2	14562095	Global analysis of protein localization in budding yeast.

P16619	CL3L1_HUMAN	C-C motif chemokine 3-like 1	1694014	Structures of human genes coding for cytokine LD78 and their expression.

Q92833	JARD2_HUMAN	Protein Jumonji	20075857	JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells.

P59055	CSRN3_MOUSE	Cysteine/serine-rich nuclear protein 3	17726538	Characterization of a family of novel cysteine- serine-rich nuclear proteins (CSRNP).

Q60848	HELLS_MOUSE	Lymphocyte-specific helicase	15647320	Lsh controls silencing of the imprinted Cdkn1c gene.

P50518	VATE1_MOUSE	V-type proton ATPase subunit E 1	11872743	A proton pump ATPase with testis-specific E1-subunit isoform required for acrosome acidification.

P83583	FER_SOLLY	Ferredoxin	12620316	Large differences in amino acid sequences among ferredoxins from several species of genus Solanum.

O15375	MOT6_HUMAN	Monocarboxylate transporter 6	9425115	Cloning and sequencing of four new mammalian monocarboxylate transporter (MCT) homologues confirms the existence of a transporter family with an ancient past.

P32942	ICAM3_HUMAN	Intercellular adhesion molecule 3	1448174	Cloning and characterization of a new intercellular adhesion molecule ICAM-R.

Q09472	EP300_HUMAN	Histone acetyltransferase p300	11430825	Regulation of human flap endonuclease-1 activity by acetylation through the transcriptional coactivator p300.

Q08886	GPB1_YEAST	Guanine nucleotide-binding protein subunit beta 1	12150916	The Galpha protein Gpa2 controls yeast differentiation by interacting with kelch repeat proteins that mimic Gbeta subunits.

Q9N428	TCL2_CAEEL	T-cell defective protein 2	12679102	tcl-2 encodes a novel protein that acts synergistically with Wnt signaling pathways in C. elegans.

O42858	SWD1_SCHPO	Set1 complex component swd1	12488447	High conservation of the Set1/Rad6 axis of histone 3 lysine 4 methylation in budding and fission yeasts.

P15384	KCNA3_RAT	Potassium voltage-gated channel subfamily A member 3	2351830	Characterization and functional expression of a rat genomic DNA clone encoding a lymphocyte potassium channel.

Q95NH6	ATTC_DROME	Attacin-C	9736738	Differential display of peptides induced during the immune response of Drosophila: a matrix-assisted laser desorption ionization time-of- flight mass spectrometry study.

P78968	PPZ_SCHPO	Serine/threonine-protein phosphatase PP-Z	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

P07213	TOM70_YEAST	Mitochondrial import receptor subunit TOM70	9774667	Preprotein translocase of the outer mitochondrial membrane: molecular dissection and assembly of the general import pore complex.

Q99607	ELF4_HUMAN	ETS-related transcription factor Elf-4	8895518	MEF, a novel transcription factor with an Elf-1 like DNA binding domain but distinct transcriptional activating properties.

Q9SSL9	PEPR1_ARATH	Leucine-rich repeat receptor-like protein kinase PEPR1	17644812	A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome.

P35125	UBP6_HUMAN	Ubiquitin carboxyl-terminal hydrolase 6	16127172	Calcium/calmodulin regulates ubiquitination of the ubiquitin-specific protease TRE17/USP6.

O14227	RDR1_SCHPO	RNA-dependent RNA polymerase 1	15615848	RNA-dependent RNA polymerase is an essential component of a self- enforcing loop coupling heterochromatin assembly to siRNA production.

P22725	WNT5A_MOUSE	Protein Wnt-5a	12952940	Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3- independent beta-catenin degradation.

P28627	IMP1_YEAST	Mitochondrial inner membrane protease subunit 1	8132591	Purified inner membrane protease I of yeast mitochondria is a heterodimer.

Q9BJZ5	FUSIL_DROME	RNA-binding protein fusilli	11133153	fusilli, an essential gene with a maternal role in Drosophila embryonic dorsal-ventral patterning.

O75582	KS6A5_HUMAN	Ribosomal protein S6 kinase alpha-5	9873047	Cloning and characterization of RLPK, a novel RSK-related protein kinase.

Q54WZ2	VACB_DICDI	Vacuolin-B	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

O43639	NCK2_HUMAN	Cytoplasmic protein NCK2	9737977	Identification of Nck family genes, chromosomal localization, expression, and signaling specificity.

P19524	MYO2_YEAST	Myosin-2	12456647	Mlc1p promotes septum closure during cytokinesis via the IQ motifs of the vesicle motor Myo2p.

Q13043	STK4_HUMAN	Serine/threonine-protein kinase 4	16751106	A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span.

Q8BQS5	ADR2_MOUSE	Adiponectin receptor protein 2	12802337	Cloning of adiponectin receptors that mediate antidiabetic metabolic effects.

O14367	GTI1_SCHPO	Gluconate transport inducer 1	9372449	Onset of gluconate-H+ symport in Schizosaccharomyces pombe is regulated by the kinases Wis1 and Pka1, and requires the gti1+ gene product.

Q27249	TPM3_CAEEL	Tropomyosin isoforms c/e	11901171	Tropomyosin inhibits ADF/cofilin-dependent actin filament dynamics.

O35764	NPTXR_RAT	Neuronal pentraxin receptor	9261167	Neuronal pentraxin receptor, a novel putative integral membrane pentraxin that interacts with neuronal pentraxin 1 and 2 and taipoxin- associated calcium-binding protein 49.

Q9CPR8	MAGG1_MOUSE	Melanoma-associated antigen G1	14593116	Necdin-related MAGE proteins differentially interact with the E2F1 transcription factor and the p75 neurotrophin receptor.

P40573	MET28_YEAST	Transcriptional activator of sulfur metabolism MET28	8665859	A heteromeric complex containing the centromere binding factor 1 and two basic leucine zipper factors, Met4 and Met28, mediates the transcription activation of yeast sulfur metabolism.

O95759	TBCD8_HUMAN	TBC1 domain family member 8	10373574	Antisense display -- a method for functional gene screening: evaluation in a cell-free system and isolation of angiogenesis-related genes.

P31997	CEAM8_HUMAN	Carcinoembryonic antigen-related cell adhesion molecule 8	2306228	Characterization of a cDNA clone encoding a new species of the nonspecific cross-reacting antigen (NCA), a member of the CEA gene family.

Q14B02	RN133_MOUSE	E3 ubiquitin-protein ligase RNF133	18574499	Mouse RING finger protein Rnf133 is a testis-specific endoplasmic reticulum-associated E3 ubiquitin ligase.

P38631	FKS1_YEAST	1,3-beta-glucan synthase component FKS1	8602515	Identification of yeast Rho1p GTPase as a regulatory subunit of 1,3- beta-glucan synthase.

O13898	PMT1_SCHPO	Dolichyl-phosphate-mannose--protein mannosyltransferase 1	15809069	Characterization of O-mannosyltransferase family in Schizosaccharomyces pombe.

Q41932	PSBQ2_ARATH	Oxygen-evolving enhancer protein 3-2, chloroplastic	11826309	Central functions of the lumenal and peripheral thylakoid proteome of Arabidopsis determined by experimentation and genome-wide prediction.

Q9Y4W2	LAS1L_HUMAN	Protein LAS1 homolog	15960975	Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

P32478	HS150_YEAST	Cell wall mannoprotein HSP150	10407261	Role of NaOH-extractable cell wall proteins Ccw5p, Ccw6p, Ccw7p and Ccw8p (members of the Pir protein family) in stability of the Saccharomyces cerevisiae cell wall.

Q9Z2K0	DEDD_RAT	Death effector domain-containing protein	9832420	DEFT, a novel death effector domain-containing molecule predominantly expressed in testicular germ cells.

Q9HBM6	TAF9B_HUMAN	Transcription initiation factor TFIID subunit 9B	15899866	TAF9b (formerly TAF9L) is a bona fide TAF that has unique and overlapping roles with TAF9.

Q93VY3	NAC72_ARATH	NAC domain-containing protein 72	15319476	Isolation and functional analysis of Arabidopsis stress-inducible NAC transcription factors that bind to a drought-responsive cis-element in the early responsive to dehydration stress 1 promoter.

P53867	ATG4_YEAST	Cysteine protease ATG4	8224160	Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae.

P11829	ACP1_ARATH	Acyl carrier protein 1, chloroplastic	2922299	DNA sequence of a genomic clone encoding an Arabidopsis acyl carrier protein (ACP).

Q9FI37	PEN4_ARATH	Thalianol synthase	18356490	Metabolic diversification -- independent assembly of operon-like gene clusters in different plants.

Q9VBW9	DANR_DROME	Protein distal antenna-related	17493605	distal antenna and distal antenna-related function in the retinal determination network during eye development in Drosophila.

Q9EPW1	BMAL1_RAT	Aryl hydrocarbon receptor nuclear translocator-like protein 1	9735336	Circadian oscillation of BMAL1, a partner of a mammalian clock gene clock, in rat suprachiasmatic nucleus.

Q8AW52	ATOH7_DANRE	Protein atonal homolog 7	11430806	Retinal ganglion cell genesis requires lakritz, a zebrafish atonal homolog.

Q9SUI4	PSAL_ARATH	Photosystem I reaction center subunit XI, chloroplastic	12766230	Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.

Q9UN19	DAPP1_HUMAN	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide	10432293	DAPP1: a dual adaptor for phosphotyrosine and 3-phosphoinositides.

P40023	EDC2_YEAST	Enhancer of mRNA-decapping protein 2	11139489	Two related proteins, Edc1p and Edc2p, stimulate mRNA decapping in Saccharomyces cerevisiae.

Q9DBL7	COASY_MOUSE	Bifunctional coenzyme A synthase	11980892	Molecular cloning of CoA synthase. The missing link in CoA biosynthesis.

Q0WRJ7	FKBP6_ARATH	FKBP-type peptidyl-prolyl cis-trans isomerase 6, chloroplastic	16894144	A redox-active FKBP-type immunophilin functions in accumulation of the photosystem II supercomplex in Arabidopsis thaliana.

Q91VH1	ADR1_MOUSE	Adiponectin receptor protein 1	12802337	Cloning of adiponectin receptors that mediate antidiabetic metabolic effects.

P48561	TRF5_YEAST	Poly(A) RNA polymerase protein 1	16373491	Contributions of Trf4p- and Trf5p-dependent polyadenylation to the processing and degradative functions of the yeast nuclear exosome.

Q9Y6X2	PIAS3_HUMAN	E3 SUMO-protein ligase PIAS3	14715251	ATBF1 enhances the suppression of STAT3 signaling by interaction with PIAS3.

P06866	HPT_RAT	Haptoglobin	6863267	Biosynthesis and processing of rat haptoglobin.

Q9LIE5	FHY3_ARATH	Protein FAR-RED ELONGATED HYPOCOTYL 3	18033885	Transposase-derived transcription factors regulate light signaling in Arabidopsis.

P83523	FER_LYCCN	Ferredoxin	12392097	Amino acid sequences of ferredoxins from Scopolia japonica and Lycium chinense: their similarities to that of Datura arborea.

Q96A58	RERG_HUMAN	Ras-related and estrogen-regulated growth inhibitor	11533059	RERG is a novel ras-related, estrogen-regulated and growth-inhibitory gene in breast cancer.

P38820	UBA4_YEAST	Adenylyltransferase and sulfurtransferase UBA4	18755837	A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae.

P29674	LHX1_XENLA	LIM/homeobox protein Lhx1	9468533	Interactions between LIM domains and the LIM domain-binding protein Ldb1.

Q9I7F7	PR2_DROME	Tyrosine-protein kinase PR2	9731193	Sampling the genomic pool of protein tyrosine kinase genes using the polymerase chain reaction with genomic DNA.

P40126	TYRP2_HUMAN	L-dopachrome tautomerase	8206391	Sequence of the human dopachrome tautomerase-encoding TRP-2 cDNA.

Q96RP9	EFGM_HUMAN	Elongation factor G, mitochondrial	19716793	EF-G2mt is an exclusive recycling factor in mammalian mitochondrial protein synthesis.

Q20168	COPB2_CAEEL	Probable coatomer subunit beta'	10588660	Receptor-mediated endocytosis in the Caenorhabditis elegans oocyte.

Q9V3B4	BG4_DROME	Death domain-containing adapter protein BG4	12433364	The Drosophila immune defense against Gram-negative infection requires the death protein dFADD.

Q9URW7	VPS17_SCHPO	Vacuolar protein sorting-associated protein 17	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q32SG3	LBD6_MAIZE	LOB domain-containing protein 6	16243907	Maize rough sheath2 and its Arabidopsis orthologue ASYMMETRIC LEAVES1 interact with HIRA, a predicted histone chaperone, to maintain knox gene silencing and determinacy during organogenesis.

Q8BGQ7	SYAC_MOUSE	Alanyl-tRNA synthetase, cytoplasmic	20010690	Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.

P04147	PABP_YEAST	Polyadenylate-binding protein, cytoplasmic and nuclear	9193001	Differential effects of aromatic and charged residue substitutions in the RNA binding domains of the yeast poly(A)-binding protein.

P22303	ACES_HUMAN	Acetylcholinesterase	1517212	Mutagenesis of human acetylcholinesterase. Identification of residues involved in catalytic activity and in polypeptide folding.

Q92993	KAT5_HUMAN	Histone acetyltransferase KAT5	14966270	Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans.

O75473	LGR5_HUMAN	Leucine-rich repeat-containing G-protein coupled receptor 5	9642114	Identification and cloning of an orphan G protein-coupled receptor of the glycoprotein hormone receptor subfamily.

Q99176	SRN2_YEAST	Protein SRN2	17442384	Molecular architecture and functional model of the complete yeast ESCRT-I heterotetramer.

Q7TN84	SYT14_MOUSE	Synaptotagmin-14	12801916	Molecular cloning, expression, and characterization of a novel class of synaptotagmin (Syt XIV) conserved from Drosophila to humans.

Q9SEX2	KTNA1_ARATH	Katanin p60 ATPase-containing subunit	12571277	The Arabidopsis lue1 mutant defines a katanin p60 ortholog involved in hormonal control of microtubule orientation during cell growth.

Q8RWC9	CIPK1_ARATH	CBL-interacting serine/threonine-protein kinase 1	10590166	Novel protein kinases associated with calcineurin B-like calcium sensors in Arabidopsis.

Q9SM23	ACBP1_ARATH	Acyl-CoA-binding domain-containing protein 1	9862500	Arabidopsis cDNA encoding a membrane-associated protein with an acyl- CoA binding domain.

Q9Y4C5	CHST2_HUMAN	Carbohydrate sulfotransferase 2	9722682	Human N-acetylglucosamine-6-O-sulfotransferase involved in the biosynthesis of 6-sulfo sialyl Lewis X: molecular cloning, chromosomal mapping, and expression in various organs and tumor cells.

Q9USU7	YHHB_SCHPO	HMG box-containing protein C28F2.11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9LK35	THE1_ARATH	Receptor-like protein kinase THESEUS 1	17644812	A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome.

O13766	MDE10_SCHPO	Zinc metalloprotease mde10	14871934	ADAM family protein Mde10 is essential for development of spore envelopes in the fission yeast Schizosaccharomyces pombe.

Q8CHN8	MASP1_RAT	Mannan-binding lectin serine protease 1	15060079	Two mechanisms for mannose-binding protein modulation of the activity of its associated serine proteases.

P02751	FINC_HUMAN	Fibronectin	1423622	The three-dimensional structure of the tenth type III module of fibronectin: an insight into RGD-mediated interactions.

P33151	CADH5_HUMAN	Cadherin-5	19996314	Cell-cell contact formation governs Ca2+ signaling by TRPC4 in the vascular endothelium: evidence for a regulatory TRPC4-beta-catenin interaction.

Q15311	RBP1_HUMAN	RalA-binding protein 1	7673236	Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity.

P38874	ELP5_YEAST	Elongator complex protein 5	11689709	Characterization of a six-subunit holo-elongator complex required for the regulated expression of a group of genes in Saccharomyces cerevisiae.

Q38914	ANT_ARATH	AP2-like ethylene-responsive transcription factor ANT	10639184	Plant organ size control: AINTEGUMENTA regulates growth and cell numbers during organogenesis.

Q9Y6H5	SNCAP_HUMAN	Synphilin-1	14506261	Siah-1 facilitates ubiquitination and degradation of synphilin-1.

Q9HCU8	DPOD4_HUMAN	DNA polymerase delta subunit 4	10751307	Identification of a fourth subunit of mammalian DNA polymerase delta.

P43634	CHA4_YEAST	Activatory protein CHA4	8889513	Cha4p of Saccharomyces cerevisiae activates transcription via serine/threonine response elements.

Q13342	LY10_HUMAN	Nuclear body protein SP140	8910577	Identification and characterization of a leukocyte-specific component of the nuclear body.

Q336R9	MSRA4_ORYSJ	Peptide methionine sulfoxide reductase A4, chloroplastic	19415325	OsMSRA4.1 and OsMSRB1.1, two rice plastidial methionine sulfoxide reductases, are involved in abiotic stress responses.

O94704	YC54_SCHPO	Uncharacterized protein C1259.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q53HL2	BOREA_HUMAN	Borealin	16291752	Molecular analysis of survivin isoforms: evidence that alternatively spliced variants do not play a role in mitosis.

Q99717	SMAD5_HUMAN	Mothers against decapentaplegic homolog 5	8673135	Mad-related genes in the human.

Q9JKS6	PCLO_RAT	Protein piccolo	11285225	An unusual C(2)-domain in the active-zone protein piccolo: implications for Ca(2+) regulation of neurotransmitter release.

Q68E01	INT3_HUMAN	Integrator complex subunit 3	16239144	Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.

Q949U1	C79F1_ARATH	Dihomomethionine N-hydroxylase	11226190	Bus, a bushy Arabidopsis CYP79F1 knockout mutant with abolished synthesis of short-chain aliphatic glucosinolates.

O14894	T4S5_HUMAN	Transmembrane 4 L6 family member 5	9479038	Identification of a new tumour-associated antigen TM4SF5 and its expression in human cancer.

P55210	CASP7_HUMAN	Caspase-7	8576161	ICE-LAP3, a novel mammalian homologue of the Caenorhabditis elegans cell death protein Ced-3 is activated during Fas- and tumor necrosis factor-induced apoptosis.

Q9UHI5	LAT2_HUMAN	Large neutral amino acids transporter small subunit 2	12117417	Transport of a neurotoxicant by molecular mimicry: the methylmercury- L-cysteine complex is a substrate for human L-type large neutral amino acid transporter (LAT) 1 and LAT2.

P04197	MYB_DROME	Myb protein	15479636	Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes.

Q61831	MK10_MOUSE	Mitogen-activated protein kinase 10	9349820	Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene.

O95297	MPZL1_HUMAN	Myelin protein zero-like protein 1	9792637	Purification and cloning of PZR, a binding protein and putative physiological substrate of tyrosine phosphatase SHP-2.

P19447	ERCC3_HUMAN	TFIIH basal transcription factor complex helicase XPB subunit	9852112	Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.

P53868	ALG9_YEAST	Probable mannosyltransferase ALG9	8692962	Stepwise assembly of the lipid-linked oligosaccharide in the endoplasmic reticulum of Saccharomyces cerevisiae: identification of the ALG9 gene encoding a putative mannosyl transferase.

Q06547	GABP1_HUMAN	GA-binding protein subunit beta-1	8441384	cDNA cloning of transcription factor E4TF1 subunits with Ets and notch motifs.

Q9V4P1	ANLN_DROME	Actin-binding protein anillin	14736750	src64 and tec29 are required for microfilament contraction during Drosophila cellularization.

P0AGA2	SECY_ECOLI	Preprotein translocase subunit SecY	2254269	Characterization of cold-sensitive secY mutants of Escherichia coli.

O54783	CHKB_RAT	Choline/ethanolamine kinase	9487136	Complementary DNA sequence for a 42 kDa rat kidney choline/ethanolamine kinase.

Q9VR82	INX6_DROME	Innexin inx6	11960713	Gap junctions in Drosophila: developmental expression of the entire innexin gene family.

Q5SW96	ARH_HUMAN	Low density lipoprotein receptor adapter protein 1	12221107	ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2.

Q9P7T4	MRC1_SCHPO	Mediator of replication checkpoint protein 1	14585996	Replication checkpoint protein Mrc1 is regulated by Rad3 and Tel1 in fission yeast.

Q70EX6	SOAT_RAT	Solute carrier family 10 member 6	15020217	Identification of a sodium-dependent organic anion transporter from rat adrenal gland.

P04253	HCY2_LIMPO	Hemocyanin II	3525550	Structure of hemocyanin II from the horseshoe crab, Limulus polyphemus. Sequences of the overlapping peptides, ordering the CNBr fragments, and the complete amino acid sequence.

Q8IXI2	MIRO1_HUMAN	Mitochondrial Rho GTPase 1	16630562	The atypical Rho GTPases Miro-1 and Miro-2 have essential roles in mitochondrial trafficking.

Q86B87	MMD4_DROME	Modifier of mdg4	15574329	The centrosomal protein CP190 is a component of the gypsy chromatin insulator.

Q06839	YP097_YEAST	PX domain-containing protein YPR097W	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P51855	GSHB_MOUSE	Glutathione synthetase	8660701	A single mouse glutathione synthetase gene encodes six mRNAs with different 5' ends.

O95243	MBD4_HUMAN	Methyl-CpG-binding domain protein 4	9774669	Identification and characterization of a family of mammalian methyl- CpG binding proteins.

P04220	MUCB_HUMAN	Ig mu heavy chain disease protein	6425189	The primary structure of mu-chain-disease protein BOT. Peculiar amino-acid sequence of the N-terminal 42 positions.

P23635	PP2A1_SCHPO	Minor serine/threonine-protein phosphatase PP2A-1 catalytic subunit	2170029	Distinct, essential roles of type 1 and 2A protein phosphatases in the control of the fission yeast cell division cycle.

Q09260	LAG3_CAEEL	Protein lag-3	10830967	LAG-3 is a putative transcriptional activator in the C. elegans Notch pathway.

P38250	IST2_YEAST	Increased sodium tolerance protein 2	11030653	Plasma membrane compartmentalization in yeast by messenger RNA transport and a septin diffusion barrier.

P25591	VAC17_YEAST	vacuole-related protein 17	12642614	Identification of an organelle-specific myosin V receptor.

O95835	LATS1_HUMAN	Serine/threonine-protein kinase LATS1	10831611	Zyxin, a regulator of actin filament assembly, targets the mitotic apparatus by interacting with h-warts/LATS1 tumor suppressor.

Q9UJY5	GGA1_HUMAN	ADP-ribosylation factor-binding protein GGA1	12505986	Divalent interaction of the GGAs with the Rabaptin-5-Rabex-5 complex.

P32461	DPH2_YEAST	Diphthamide biosynthesis protein 2	14562095	Global analysis of protein localization in budding yeast.

P43593	UBP6_YEAST	Ubiquitin carboxyl-terminal hydrolase 6	12408819	Multiple associated proteins regulate proteasome structure and function.

P38251	RFC5_YEAST	Replication factor C subunit 5	11389843	Identification of RFC(Ctf18p, Ctf8p, Dcc1p): an alternative RFC complex required for sister chromatid cohesion in S. cerevisiae.

Q8WWW0	RASF5_HUMAN	Ras association domain-containing protein 5	12845325	RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1.

Q9BXA6	TSSK6_HUMAN	Testis-specific serine/threonine-protein kinase 6	15870294	Identification and characterization of SSTK, a serine/threonine protein kinase essential for male fertility.

O00303	EIF3F_HUMAN	Eukaryotic translation initiation factor 3 subunit F	17581632	Reconstitution reveals the functional core of mammalian eIF3.

Q63488	S20A2_RAT	Sodium-dependent phosphate transporter 2	8278411	Cloning of the cellular receptor for amphotropic murine retroviruses reveals homology to that for gibbon ape leukemia virus.

Q9H305	LITFL_HUMAN	LITAF-like protein	10570909	C16orf5, a novel proline-rich gene at 16p13.3, is highly expressed in the brain.

Q15546	PAQRB_HUMAN	Monocyte to macrophage differentiation protein	7503749	Molecular cloning of a novel macrophage maturation-associated transcript encoding a protein with several potential transmembrane domains.

P21145	MAL_HUMAN	Myelin and lymphocyte protein	8132541	Genomic structure and subcellular localization of MAL, a human T- cell-specific proteolipid protein.

O95416	SOX14_HUMAN	Transcription factor SOX-14	9925951	Characterisation and mapping of the human SOX14 gene.

O94679	CND1_SCHPO	Condensin complex subunit 1	10485849	Fission yeast condensin complex: essential roles of non-SMC subunits for condensation and Cdc2 phosphorylation of Cut3/SMC4.

Q8R5M8	CADM1_MOUSE	Cell adhesion molecule 1	15811952	The tumor suppressor TSLC1/NECL-2 triggers NK-cell and CD8+ T-cell responses through the cell-surface receptor CRTAM.

Q9UJ96	KCNG2_HUMAN	Potassium voltage-gated channel subfamily G member 2	10551266	Structural and functional characterization of Kv6.2, a new gamma- subunit of voltage-gated potassium channel.

O88879	APAF_MOUSE	Apoptotic protease-activating factor 1	9753320	Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development.

Q16520	BATF_HUMAN	Basic leucine zipper transcriptional factor ATF-like	8954125	IFP 35 forms complexes with B-ATF, a member of the AP1 family of transcription factors.

Q9HBG4	VPP4_HUMAN	V-type proton ATPase 116 kDa subunit a isoform 4	10973252	Mutations in ATP6N1B, encoding a new kidney vacuolar proton pump 116- kD subunit, cause recessive distal renal tubular acidosis with preserved hearing.

Q8I8V0	TAD2B_DROME	Transcriptional adapter 2B	12482983	Two different Drosophila ADA2 homologues are present in distinct GCN5 histone acetyltransferase-containing complexes.

O60542	PSPN_HUMAN	Persephin	9491986	Persephin, a novel neurotrophic factor related to GDNF and neurturin.

Q9R1I1	CHST4_MOUSE	Carbohydrate sulfotransferase 4	14597732	Lymphocyte-HEV interactions in lymph nodes of a sulfotransferase- deficient mouse.

O14512	SOCS7_HUMAN	Suppressor of cytokine signaling 7	9344857	A novel ligand for an SH3 domain of the adaptor protein Nck bears an SH2 domain and nuclear signaling motifs.

O14681	EI24_HUMAN	Etoposide-induced protein 2.4 homolog	9305847	A model for p53-induced apoptosis.

Q8CG64	FKRP_MOUSE	Fukutin-related protein	19900540	Mutations alter secretion of fukutin-related protein.

P97686	NRCAM_RAT	Neuronal cell adhesion molecule	8947556	Molecular composition of the node of Ranvier: identification of ankyrin-binding cell adhesion molecules neurofascin (mucin+/third FNIII domain-) and NrCAM at nodal axon segments.

O24646	HY5_ARATH	Transcription factor HY5	12028569	Biochemical evidence for ubiquitin ligase activity of the Arabidopsis COP1 interacting protein 8 (CIP8).

Q9Z252	LIN7B_RAT	Protein lin-7 homolog B	14960569	A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels.

P32314	FOXN2_HUMAN	Forkhead box protein N2	1639393	Characterization and chromosomal mapping of the gene encoding the cellular DNA binding protein HTLF.

O14656	TOR1A_HUMAN	Torsin-1A	15767459	The AAA+ protein torsinA interacts with a conserved domain present in LAP1 and a novel ER protein.

Q9SEE5	GALK1_ARATH	Galactokinase	10344205	The arabinose kinase, ARA1, gene of Arabidopsis is a novel member of the galactose kinase gene family.

P12504	VIF_HV1N5	Virion infectivity factor	15367624	Ring finger protein ZIN interacts with human immunodeficiency virus type 1 Vif.

P82600	PERC_AEDAE	Chorion peroxidase	10871050	Purification and characterization of chorion peroxidase from Aedes aegypti eggs.

O00311	CDC7_HUMAN	Cell division cycle 7-related protein kinase	9405610	Identification and characterization of a human protein kinase related to budding yeast Cdc7p.

O94505	DPNP_SCHPO	3'(2'),5'-bisphosphate nucleotidase	10850973	Tol1, a fission yeast phosphomonoesterase, is an in vivo target of lithium, and its deletion leads to sulfite auxotrophy.

Q9BRP8	WIBG_HUMAN	Partner of Y14 and mago	18026120	PYM binds the cytoplasmic exon-junction complex and ribosomes to enhance translation of spliced mRNAs.

O14867	BACH1_HUMAN	Transcription regulator protein BACH1	9479503	Characterization of a human homolog (BACH1) of the mouse Bach1 gene encoding a BTB-basic leucine zipper transcription factor and its mapping to chromosome 21q22.1.

Q13485	SMAD4_HUMAN	Mothers against decapentaplegic homolog 4	19135894	FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination.

P14770	GPIX_HUMAN	Platelet glycoprotein IX	2771955	Human platelet glycoprotein IX: an adhesive prototype of leucine-rich glycoproteins with flank-center-flank structures.

Q9USQ6	SYJ2_SCHPO	Inositol-1,4,5-trisphosphate 5-phosphatase 2	12529438	Global transcriptional responses of fission yeast to environmental stress.

P0A830	DCTA_ECOLI	Aerobic C4-dicarboxylate transport protein	10482502	Inactivation and regulation of the aerobic C(4)-dicarboxylate transport (dctA) gene of Escherichia coli.

P39011	BEM4_YEAST	Bud emergence protein 4	8754839	Identification of the bud emergence gene BEM4 and its interactions with rho-type GTPases in Saccharomyces cerevisiae.

Q08891	FACR2_ARATH	Fatty acyl-CoA reductase 2	19062129	Functional expression of five Arabidopsis fatty acyl-CoA reductase genes in Escherichia coli.

Q54QT7	CBPC_DICDI	Calcium-binding protein C	9883904	Cloning of a cDNA encoding a new calcium-binding protein from Dictyostelium discoideum and its developmental regulation.

P55316	FOXG1_HUMAN	Forkhead box protein G1	7599184	The genes for human brain factor 1 and 2, members of the fork head gene family, are clustered on chromosome 14q.

Q9M088	E135_ARATH	Glucan endo-1,3-beta-glucosidase 5	12805588	Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis.

P28473	GBRG3_RAT	Gamma-aminobutyric acid receptor subunit gamma-3	1311098	The third gamma subunit of the gamma-aminobutyric acid type A receptor family.

O82302	P2C29_ARATH	Protein phosphatase 2C 29	17079273	POL and PLL1 phosphatases are CLAVATA1 signaling intermediates required for Arabidopsis shoot and floral stem cells.

Q9LFT8	CDKC1_ARATH	Cyclin-dependent kinase C-1	12678503	Novel complexes of cyclin-dependent kinases and a cyclin-like protein from Arabidopsis thaliana with a function unrelated to cell division.

Q03029	SPO19_YEAST	Sporulation-specific protein 19	10383953	Amino acid residues in the omega-minus region participate in cellular localization of yeast glycosylphosphatidylinositol-attached proteins.

P30153	2AAA_HUMAN	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform	17245430	A specific PP2A regulatory subunit, B56gamma, mediates DNA damage- induced dephosphorylation of p53 at Thr55.

P09960	LKHA4_HUMAN	Leukotriene A-4 hydrolase	1881903	Leukotriene A4 hydrolase: determination of the three zinc-binding ligands by site-directed mutagenesis and zinc analysis.

P47124	HOC1_YEAST	Putative glycosyltransferase HOC1	9434768	Novel membrane protein complexes for protein glycosylation in the yeast Golgi apparatus.

P51786	ZN157_HUMAN	Zinc finger protein 157	8586441	Cloning and characterization of a novel zinc finger gene in Xp11.2.

O96790	DPGN_DIPMA	Serine protease inhibitor dipetalogastin	10702701	Biochemical characterization of a thrombin inhibitor from the bloodsucking bug Dipetalogaster maximus.

Q54E04	VATM_DICDI	Vacuolar proton translocating ATPase 100 kDa subunit	12082150	Dynamics of the vacuolar H(+)-ATPase in the contractile vacuole complex and the endosomal pathway of Dictyostelium cells.

P40308	TGL3_YEAST	Lipase 3	10515935	Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiae.

Q9BZM5	N2DL2_HUMAN	NKG2D ligand 2	11239445	ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor.

Q8VI67	SP7_MOUSE	Transcription factor Sp7	19927124	Regulation of the osteoblast-specific transcription factor Osterix by NO66, a Jumonji family histone demethylase.

Q9ZRF9	RPK1_ARATH	Probable LRR receptor-like serine/threonine-protein kinase RPK1	9112773	Identification of a receptor-like protein kinase gene rapidly induced by abscisic acid, dehydration, high salt, and cold treatments in Arabidopsis thaliana.

Q07266	DREB_RAT	Drebrin	1611026	Cloning of drebrin A and induction of neurite-like processes in drebrin-transfected cells.

P42684	ABL2_HUMAN	Tyrosine-protein kinase ABL2	2198571	The complete coding sequence of arg defines the Abelson subfamily of cytoplasmic tyrosine kinases.

Q9I8W5	CMLO_XENLA	Probable N-acetyltransferase camello	11397015	Overexpression of camello, a member of a novel protein family, reduces blastomere adhesion and inhibits gastrulation in Xenopus laevis.

P25867	UBCD1_DROME	Ubiquitin-conjugating enzyme E2-17 kDa	9106658	UbcD1, a Drosophila ubiquitin-conjugating enzyme required for proper telomere behavior.

P31539	HS104_YEAST	Heat shock protein 104	10467108	Direct evidence for the intracellular localization of Hsp104 in Saccharomyces cerevisiae by immunoelectron microscopy.

P36088	FRMSR_YEAST	Free methionine-R-sulfoxide reductase	19049972	Functional analysis of free methionine-R-sulfoxide reductase from Saccharomyces cerevisiae.

Q9P6N9	PER1_SCHPO	Protein PER1 homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P78310	CXAR_HUMAN	Coxsackievirus and adenovirus receptor	9096397	HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses.

Q9WTI7	MYO1C_MOUSE	Myosin-Ic	15976448	PHR1, an integral membrane protein of the inner ear sensory cells, directly interacts with myosin 1c and myosin VIIa.

O13842	CDA1_SCHPO	Chitin deacetylase 1	15862318	cda1+, encoding chitin deacetylase is required for proper spore formation in Schizosaccharomyces pombe.

Q9P6L5	SLA2_SCHPO	Endocytosis protein end4	15300681	Characterization of end4+, a gene required for endocytosis in Schizosaccharomyces pombe.

Q505F1	NR2C1_MOUSE	Nuclear receptor subfamily 2 group C member 1	8858600	Molecular cloning and characterization of a mouse nuclear orphan receptor expressed in embryos and testes.

Q16656	NRF1_HUMAN	Nuclear respiratory factor 1	7629110	Structure, expression, and chromosomal assignment of the human gene encoding nuclear respiratory factor 1.

Q13114	TRAF3_HUMAN	TNF receptor-associated factor 3	7530216	A novel member of the TRAF family of putative signal transducing proteins binds to the cytosolic domain of CD40.

Q9SY65	ASK18_ARATH	SKP1-like protein 18	18036202	SKP2A, an F-box protein that regulates cell division, is degraded via the ubiquitin pathway.

Q02874	H2AY_RAT	Core histone macro-H2A.1	1529340	MacroH2A, a core histone containing a large nonhistone region.

Q06179	FMP27_YEAST	Protein FMP27, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q5FWY4	MCM6M_XENLA	Maternal DNA replication licensing factor mcm6	9214646	The RLF-M component of the replication licensing system forms complexes containing all six MCM/P1 polypeptides.

Q04844	ACHE_HUMAN	Acetylcholine receptor subunit epsilon	8872460	New mutations in acetylcholine receptor subunit genes reveal heterogeneity in the slow-channel congenital myasthenic syndrome.

Q13547	HDAC1_HUMAN	Histone deacetylase 1	18093978	Nuclear tumor necrosis factor receptor-associated factor 6 in lymphoid cells negatively regulates c-Myb-mediated transactivation through small ubiquitin-related modifier-1 modification.

O60085	AMPM2_SCHPO	Methionine aminopeptidase 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P04279	SEMG1_HUMAN	Semenogelin-1	1517240	Gene structure of semenogelin I and II. The predominant proteins in human semen are encoded by two homologous genes on chromosome 20.

P48732	DET1_ARATH	Light-mediated development protein DET1	8033202	DET1, a negative regulator of light-mediated development and gene expression in Arabidopsis, encodes a novel nuclear-localized protein.

Q23924	COPB_DICDI	Coatomer subunit beta	10887966	Cloning and characterization of beta-COP from Dictyostelium discoideum.

P05108	CP11A_HUMAN	Cholesterol side-chain cleavage enzyme, mitochondrial	11502818	Heterozygous mutation in the cholesterol side chain cleavage enzyme (P450scc) gene in a patient with 46,XY sex reversal and adrenal insufficiency.

P53224	ORM1_YEAST	Protein ORM1	14562095	Global analysis of protein localization in budding yeast.

Q9JIX5	CHD8_RAT	Chromodomain-helicase-DNA-binding protein 8	10921920	A novel beta-catenin-binding protein inhibits beta-catenin-dependent Tcf activation and axis formation.

Q13526	PIN1_HUMAN	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	11470801	Identification of a novel kinesin-related protein, KRMP1, as a target for mitotic peptidyl-prolyl isomerase Pin1.

P21784	RAG2_MOUSE	V(D)J recombination-activating protein 2	15964836	A PHD finger motif in the C terminus of RAG2 modulates recombination activity.

Q96G01	BICD1_HUMAN	Protein bicaudal D homolog 1	9367685	A human homologue (BICD1) of the Drosophila bicaudal-D gene.

Q93ZB2	KO1_ARATH	Ent-kaurene oxidase, chloroplastic	9952446	Arabidopsis ent-kaurene oxidase catalyzes three steps of gibberellin biosynthesis.

P67809	YBOX1_HUMAN	Nuclease-sensitive element-binding protein 1	19029303	Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs.

P54322	PYRDB_LACLM	Dihydroorotate dehydrogenase B, catalytic subunit	11188687	Structure of dihydroorotate dehydrogenase B: electron transfer between two flavin groups bridged by an iron-sulphur cluster.

Q6K9G3	AMT13_ORYSJ	Ammonium transporter 1 member 3	12610225	Constitutive expression of a novel-type ammonium transporter OsAMT2 in rice plants.

P82972	VNP_PSEPC	Natriuretic peptide PNP	14741349	Functional and structural characterization of a novel member of the natriuretic family of peptides from the venom of Pseudocerastes persicus.

O82660	P2SAF_ARATH	Photosystem II stability/assembly factor HCF136, chloroplastic	9736608	A nuclear-encoded protein of prokaryotic origin is essential for the stability of photosystem II in Arabidopsis thaliana.

P05062	ALDOB_HUMAN	Fructose-bisphosphate aldolase B	3383242	Catalytic deficiency of human aldolase B in hereditary fructose intolerance caused by a common missense mutation.

Q8NBT2	SPC24_HUMAN	Kinetochore protein Spc24	14699129	Identification of two novel components of the human NDC80 kinetochore complex.

Q8NJJ1	MTLD_ASPNG	Mannitol-1-phosphate 5-dehydrogenase	7030216	Purification and kinetic characterization of mannitol-1-phosphate dehydrogenase from Aspergillus niger.

Q10124	PQE1_CAEEL	Putative RNA exonuclease pqe-1	12486229	Glutamine/proline-rich PQE-1 proteins protect Caenorhabditis elegans neurons from huntingtin polyglutamine neurotoxicity.

Q8VCT4	CES3_MOUSE	Carboxylesterase 3	10518925	cDNA cloning, characterization and stable expression of novel human brain carboxylesterase.

P30926	ACHB4_HUMAN	Neuronal acetylcholine receptor subunit beta-4	8906617	Comparative structure of human neuronal alpha 2-alpha 7 and beta 2- beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits.

Q15269	PWP2_HUMAN	Periodic tryptophan protein 2 homolog	8893822	A periodic tryptophan protein 2 gene homologue (PWP2H) in the candidate region of progressive myoclonus epilepsy on 21q22.3.

P08311	CATG_HUMAN	Cathepsin G	1861080	Proteolysis of C3 on U937 cell plasma membranes. Purification of cathepsin G.

O42917	ESO1_SCHPO	N-acetyltransferase eso1	10779336	Fission yeast eso1p is required for establishing sister chromatid cohesion during S phase.

Q810C1	SLIK1_MOUSE	SLIT and NTRK-like protein 1	14550773	Identification and characterization of Slitrk, a novel neuronal transmembrane protein family controlling neurite outgrowth.

Q91Y80	3BP5_RAT	SH3 domain-binding protein 5	15158451	Phosphorylation of the mitochondrial protein Sab by stress-activated protein kinase 3.

O14063	IMA1_SCHPO	Importin subunit alpha-1	9740803	Mutations in fission yeast Cut15, an importin alpha homolog, lead to mitotic progression without chromosome condensation.

P59996	PCSK9_RAT	Proprotein convertase subtilisin/kexin type 9	14622975	Functional characterization of Narc 1, a novel proteinase related to proteinase K.

Q99805	TM9S2_HUMAN	Transmembrane 9 superfamily member 2	9729438	Characterization of a 76 kDa endosomal, multispanning membrane protein that is highly conserved throughout evolution.

Q3TDK6	ROGDI_MOUSE	Protein rogdi homolog	11740862	Genetic approach and phenotype-based complementation screening for identification of stroma cell-derived proteins involved in cell proliferation.

Q9YGC3	CXR4A_XENLA	C-X-C chemokine receptor type 4-A	15740585	The mode and molecular mechanisms of the migration of presumptive PGC in the endoderm cell mass of Xenopus embryos.

P39019	RS19_HUMAN	40S ribosomal protein S19	9988267	The gene encoding ribosomal protein S19 is mutated in Diamond- Blackfan anaemia.

Q96533	ADHX_ARATH	Alcohol dehydrogenase class-3	8944774	Arabidopsis formaldehyde dehydrogenase. Molecular properties of plant class III alcohol dehydrogenase provide further insights into the origins, structure and function of plant class P and liver class I alcohol dehydrogenases.

Q9UBK2	PRGC1_HUMAN	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha	10585775	Human peroxisome proliferator activated receptor gamma coactivator 1 (PPARGC1) gene: cDNA sequence, genomic organization, chromosomal localization, and tissue expression.

P51815	ZN75D_HUMAN	Zinc finger protein 75D	8288223	ZNF75: isolation of a cDNA clone of the KRAB zinc finger gene subfamily mapped in YACs 1 Mb telomeric of HPRT.

O94627	RNH2B_SCHPO	Ribonuclease H2 subunit B	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P24723	KPCL_HUMAN	Protein kinase C eta type	1986216	Isolation and characterization of PKC-L, a new member of the protein kinase C-related gene family specifically expressed in lung, skin, and heart.

Q5AUM3	ABNC_EMENI	Arabinan endo-1,5-alpha-L-arabinosidase C	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

Q12830	BPTF_HUMAN	Nucleosome-remodeling factor subunit BPTF	10403843	DNA binding activity of the fetal Alz-50 clone 1 (FAC1) protein is enhanced by phosphorylation.

P07333	CSF1R_HUMAN	Macrophage colony-stimulating factor 1 receptor	2421165	Structural alteration of viral homologue of receptor proto-oncogene fms at carboxyl terminus.

P63057	NOE3_RAT	Noelin-3	12019210	Optimedin: a novel olfactomedin-related protein that interacts with myocilin.

P49107	PSAN_ARATH	Photosystem I reaction center subunit N, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

P25189	MYP0_HUMAN	Myelin protein P0	7506095	De novo mutation of the myelin P0 gene in Dejerine-Sottas disease (hereditary motor and sensory neuropathy type III).

Q9SU40	SKU5_ARATH	Monocopper oxidase-like protein SKU5	12119380	The Arabidopsis SKU5 gene encodes an extracellular glycosyl phosphatidylinositol-anchored glycoprotein involved in directional root growth.

Q99MB7	RN141_MOUSE	RING finger protein 141	12804569	Molecular cloning and characterization of a mouse spermatogenesis- related ring finger gene znf230.

P0A6U5	RSMG_ECOLI	Ribosomal RNA small subunit methyltransferase G	17238915	Loss of a conserved 7-methylguanosine modification in 16S rRNA confers low-level streptomycin resistance in bacteria.

P29016	CD1B_HUMAN	T-cell surface glycoprotein CD1b	2701945	Expression of cDNA clones encoding the thymocyte antigens CD1a, b, c demonstrates a hierarchy of exclusion in fibroblasts.

O88621	FOXH1_MOUSE	Forkhead box protein H1	9702197	Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2.

P84277	PA1D_RANPA	Palustrin-1d	11087945	Multiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris.

Q9BZR6	RTN4R_HUMAN	Reticulon-4 receptor	14966521	LINGO-1 is a component of the Nogo-66 receptor/p75 signaling complex.

Q8IZP0	ABI1_HUMAN	Abl interactor 1	12681507	Induction of colonic epithelial cell apoptosis by p47-dependent oxidants(1).

P17658	KCNA6_HUMAN	Potassium voltage-gated channel subfamily A member 6	2347305	Cloning and expression of a human voltage-gated potassium channel. A novel member of the RCK potassium channel family.

P13185	KIN1_YEAST	Serine/threonine protein kinase KIN1	15563607	The yeast par-1 homologs kin1 and kin2 show genetic and physical interactions with components of the exocytic machinery.

Q9YGV1	DERR_XENLA	Derriere protein	11256621	The TGF-beta family member derriere is involved in regulation of the establishment of left-right asymmetry.

P78549	NTHL1_HUMAN	Endonuclease III-like protein 1	10882850	Cell-cycle regulation, intracellular sorting and induced overexpression of the human NTH1 DNA glycosylase involved in removal of formamidopyrimidine residues from DNA.

Q2VPK5	CTU2_HUMAN	Cytoplasmic tRNA 2-thiolation protein 2	19017811	A functional proteomics approach links the ubiquitin-related modifier Urm1 to a tRNA modification pathway.

P47052	DHSX_YEAST	Succinate dehydrogenase [ubiquinone] flavoprotein subunit 2, mitochondrial	9730279	Suppression of sdh1 mutations by the SDH1b gene of Saccharomyces cerevisiae.

O81283	TC159_ARATH	Translocase of chloroplast 159, chloroplastic	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

Q96LT9	RBM40_HUMAN	RNA-binding protein 40	15146077	The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome.

P24310	CX7A1_HUMAN	Cytochrome c oxidase subunit 7A1, mitochondrial	1327965	Tissue-specific expression and chromosome assignment of genes specifying two isoforms of subunit VIIa of human cytochrome c oxidase.

P84389	PLYB2_POLPI	Polybine-2	15572194	Structural and functional characterization of N-terminally blocked peptides isolated from the venom of the social wasp Polybia paulista.

P01730	CD4_HUMAN	T-cell surface glycoprotein CD4	8124721	Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain.

P05735	RL19_YEAST	60S ribosomal protein L19	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

P87160	RHGA_ASPNG	Rhamnogalacturonase A	9212401	Cloning and characterization of two rhamnogalacturonan hydrolase genes from Aspergillus niger.

P0ABZ6	SURA_ECOLI	Chaperone surA	2165476	surA, an Escherichia coli gene essential for survival in stationary phase.

Q99P84	PLCE1_RAT	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon-1	11179219	Phospholipase C(epsilon): a novel Ras effector.

O75382	TRIM3_HUMAN	Tripartite motif-containing protein 3	19460345	Monoubiquitinylation regulates endosomal localization of Lst2, a negative regulator of EGF receptor signaling.

O74733	CFT1_SCHPO	Protein cft1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q39026	MPK6_ARATH	Mitogen-activated protein kinase 6	15225555	The MKK2 pathway mediates cold and salt stress signaling in Arabidopsis.

Q9VNJ5	DISP_DROME	Protein dispatched	10619433	Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells.

P40890	VTH2_YEAST	Protein VTH2	8662642	Multiple pathways for vacuolar sorting of yeast proteinase A.

P35122	UCHL_DROME	Ubiquitin carboxyl-terminal hydrolase	7683284	Cloning and analysis of expression of a ubiquitin carboxyl terminal hydrolase expressed during oogenesis in Drosophila melanogaster.

O64645	SOC1_ARATH	MADS-box protein SOC1	10995392	The AGAMOUS-LIKE 20 MADS domain protein integrates floral inductive pathways in Arabidopsis.

P92994	TCMO_ARATH	Trans-cinnamate 4-monooxygenase	9085571	Isolation of a cDNA and a genomic clone encoding cinnamate 4- hydroxylase from Arabidopsis and its expression manner in planta.

Q9NY59	NSMA2_HUMAN	Sphingomyelin phosphodiesterase 3	10823942	Cloning and characterization of the mammalian brain-specific, Mg2+- dependent neutral sphingomyelinase.

Q9Z1M7	LARGE_MOUSE	Glycosyltransferase-like protein LARGE1	11381262	Mutant glycosyltransferase and altered glycosylation of alpha- dystroglycan in the myodystrophy mouse.

P47083	MPP10_YEAST	U3 small nucleolar RNA-associated protein MPP10	15590835	The small-subunit processome is a ribosome assembly intermediate.

Q9D0M5	DYL2_MOUSE	Dynein light chain 2, cytoplasmic	11546872	Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis.

Q91Y57	SIG12_MOUSE	Sialic acid-binding Ig-like lectin 12	11171044	mSiglec-E, a novel mouse CD33-related siglec (sialic acid-binding immunoglobulin-like lectin) that recruits Src homology 2 (SH2)-domain- containing protein tyrosine phosphatases SHP-1 and SHP-2.

Q08125	IL5_RAT	Interleukin-5	1653053	The rat interleukin-5 gene: characterization and expression by retroviral gene transfer and polymerase chain reaction.

Q04659	CSM3_YEAST	Chromosome segregation in meiosis protein 3	14562095	Global analysis of protein localization in budding yeast.

Q6Z2T3	NIP21_ORYSJ	Aquaporin NIP2-1	16572174	A silicon transporter in rice.

P61964	WDR5_HUMAN	WD repeat-containing protein 5	15960975	Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

Q9M274	NAC66_ARATH	NAC domain-containing protein 66	16214898	The NAC transcription factors NST1 and NST2 of Arabidopsis regulate secondary wall thickenings and are required for anther dehiscence.

Q75JI3	NSF_DICDI	Vesicle-fusing ATPase	12183371	Cell polarity and locomotion, as well as endocytosis, depend on NSF.

O35889	AFAD_RAT	Afadin	9334353	Afadin: a novel actin filament-binding protein with one PDZ domain localized at cadherin-based cell-to-cell adherens junction.

Q9MZ03	CD38_RABIT	ADP-ribosyl cyclase 1	10891341	Molecular cloning, expression, and functional characterization of a novel member of the CD38 family of ADP-ribosyl cyclases.

Q00987	MDM2_HUMAN	E3 ubiquitin-protein ligase Mdm2	15878855	{beta}-Arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth factor-1 receptor by acting as adaptor for the MDM2 E3 ligase.

P52554	PFD6_CAEEL	Probable prefoldin subunit 6	11099033	Functional genomic analysis of C. elegans chromosome I by systematic RNA interference.

Q9UHV7	MED13_HUMAN	Mediator of RNA polymerase II transcription subunit 13	10198638	Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators.

P50395	GDIB_HUMAN	Rab GDP dissociation inhibitor beta	7543319	Expression patterns of two human genes coding for different rab GDP- dissociation inhibitors (GDIs), extremely conserved proteins involved in cellular transport.

Q7KHG2	JING_DROME	Zinc finger protein jing	11152631	Jing: a downstream target of slbo required for developmental control of border cell migration.

Q8IC19	YPF13_PLAF7	Uncharacterized protein PF07_0021	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

P23819	GRIA2_MOUSE	Glutamate receptor 2	14687553	Glutamatergic plasticity by synaptic delivery of GluR-B(long)- containing AMPA receptors.

Q9P2M7	CING_HUMAN	Cingulin	12023291	Evidence for a functional interaction between cingulin and ZO-1 in cultured cells.

P15648	HSL33_DICDI	HssA/B-like protein 33	2161991	Developmental regulation of cell-type-enriched mRNAs in Dictyostelium discoideum.

Q6J756	CAN11_MOUSE	Calpain-11	16541461	Calpain 11 is unique to mouse spermatogenic cells.

Q9Z183	PADI4_MOUSE	Protein-arginine deiminase type-4	10092850	Molecular cloning of cDNAs of mouse peptidylarginine deiminase type I, type III and type IV, and the expression pattern of type I in mouse.

P10152	ANG1_BOVIN	Angiogenin-1	3064806	Isolation of bovine angiogenin using a placental ribonuclease inhibitor binding assay.

Q9Y6J3	SMA5O_HUMAN	SMAD5 opposite strand protein	10049768	An antisense transcript to SMAD5 expressed in fetal and tumor tissues.

Q16853	AOC3_HUMAN	Membrane primary amine oxidase	8972912	Cloning and sequencing of a copper-containing, topaquinone-containing monoamine oxidase from human placenta.

Q8AV66	TBX6_XENLA	T-box transcription factor TBX6	16953215	Xenopus Tbx6 mediates posterior patterning via activation of Wnt and FGF signalling.

Q63270	ACOC_RAT	Cytoplasmic aconitate hydratase	1527027	The iron-responsive element binding protein. Purification, cloning, and regulation in rat liver.

P40568	DSN1_YEAST	Kinetochore-associated protein DSN1	12455957	Nnf1p, Dsn1p, Mtw1p, and Nsl1p: a new group of proteins important for chromosome segregation in Saccharomyces cerevisiae.

P46867	KLP68_DROME	Kinesin-like protein Klp68D	7525600	Characterization of the KLP68D kinesin-like protein in Drosophila: possible roles in axonal transport.

P41743	KPCI_HUMAN	Protein kinase C iota type	11257119	Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures.

Q9URY9	YI06_SCHPO	Uncharacterized hemerythrin-like protein C869.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q00960	NMDE2_RAT	Glutamate [NMDA] receptor subunit epsilon-2	7569905	Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95.

P25632	RSC6_YEAST	Chromatin structure-remodeling complex protein RSC6	8980231	RSC, an essential, abundant chromatin-remodeling complex.

P07279	RL18_YEAST	60S ribosomal protein L18	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q8CI11	GNL3_MOUSE	Guanine nucleotide-binding protein-like 3	12464630	A nucleolar mechanism controlling cell proliferation in stem and cancer cells.

Q9LLR7	NLTP3_ARATH	Non-specific lipid-transfer protein 3	10940464	Lipid transfer proteins are encoded by a small multigene family in Arabidopsis thaliana.

Q12254	SVS1_YEAST	Protein SVS1	7489911	Cloning and characterization of the Saccharomyces cerevisiae SVS1 gene which encodes a serine- and threonine-rich protein required for vanadate resistance.

Q9P382	NUP82_SCHPO	Nucleoporin nup82	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P38063	KPR4_YEAST	Ribose-phosphate pyrophosphokinase 4	15280369	Heterooligomeric phosphoribosyl diphosphate synthase of Saccharomyces cerevisiae: combinatorial expression of the five PRS genes in Escherichia coli.

P21760	EXFAB_CHICK	Extracellular fatty acid-binding protein	8702740	The developmentally regulated avian Ch21 lipocalin is an extracellular fatty acid-binding protein.

Q8LAW2	AFR_ARATH	F-box protein AFR	12795696	Protein interaction analysis of SCF ubiquitin E3 ligase subunits from Arabidopsis.

P91428	COQ4_CAEEL	Ubiquinone biosynthesis protein coq-4, mitochondrial	12709403	Silencing of ubiquinone biosynthesis genes extends life span in Caenorhabditis elegans.

Q12834	CDC20_HUMAN	Cell division cycle protein 20 homolog	17443180	Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities.

Q9NPB6	PAR6A_HUMAN	Partitioning defective 6 homolog alpha	10954424	The mammalian homologue of the Caenorhabditis elegans polarity protein PAR-6 is a binding partner for the Rho GTPases Cdc42 and Rac1.

Q99JB7	AMNLS_MOUSE	Protein amnionless	15342463	Mouse amnionless, which is required for primitive streak assembly, mediates cell-surface localization and endocytic function of cubilin on visceral endoderm and kidney proximal tubules.

Q9HDZ3	MUG82_SCHPO	Meiotically up-regulated gene 82 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UQF2	JIP1_HUMAN	C-Jun-amino-terminal kinase-interacting protein 1	10574993	Interaction of c-Jun amino-terminal kinase interacting protein-1 with p190 rhoGEF and its localization in differentiated neurons.

P05432	ERRFI_RAT	ERBB receptor feedback inhibitor 1	17599051	The evolutionarily conserved EBR module of RALT/MIG6 mediates suppression of the EGFR catalytic activity.

P0A759	NAGB_ECOLI	Glucosamine-6-phosphate deaminase	1734962	Identification of two cysteine residues forming a pair of vicinal thiols in glucosamine-6-phosphate deaminase from Escherichia coli and a study of their functional role by site-directed mutagenesis.

Q53084	PSA2_RHOER	Proteasome subunit alpha 2	7583123	The first characterization of a eubacterial proteasome: the 20S complex of Rhodococcus.

Q03012	SPP1_YEAST	COMPASS component SPP1	11805083	COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression.

Q5SMQ9	PIN1_ORYSJ	Auxin efflux carrier component 1	16085936	A PIN1 family gene, OsPIN1, involved in auxin-dependent adventitious root emergence and tillering in rice.

P0C1R0	PROTO_POLPI	Polybia-CP	16129513	Structural and functional characterization of two novel peptide toxins isolated from the venom of the social wasp Polybia paulista.

P49711	CTCF_HUMAN	Transcriptional repressor CTCF	19322193	Architectural roles of multiple chromatin insulators at the human apolipoprotein gene cluster.

Q08231	THP1_YEAST	Nuclear mRNA export protein THP1	12411502	The mRNA export machinery requires the novel Sac3p-Thp1p complex to dock at the nucleoplasmic entrance of the nuclear pores.

O44342	WBL_DROME	Protein windbeutel	12941941	Crystal structure and functional analysis of Drosophila Wind, a protein-disulfide isomerase-related protein.

Q8MXI4	PMK2_CAEEL	Mitogen-activated protein kinase pmk-2	11703092	Isolation and characterization of pmk-(1-3): three p38 homologs in Caenorhabditis elegans.

P31977	EZRI_RAT	Ezrin	7640303	Transcriptional regulation of the ezrin gene during rat intestinal development and epithelial differentiation.

P0C152	MKS3_RAT	Meckelin	19515853	Ciliary and centrosomal defects associated with mutation and depletion of the Meckel syndrome genes MKS1 and MKS3.

P48994	TRPL_DROME	Transient-receptor-potential-like protein	8670063	Identification and characterization of two distinct calmodulin- binding sites in the Trpl ion-channel protein of Drosophila melanogaster.

P14480	FIBB_RAT	Fibrinogen beta chain	7841303	Cloning of the complete coding sequence of rat fibrinogen B beta chain cDNA: interspecies conservation of fibrin beta 15-42 primary structure.

Q8R0I0	ACE2_MOUSE	Angiotensin-converting enzyme 2	12075344	Angiotensin-converting enzyme 2 is an essential regulator of heart function.

O95278	EPM2A_HUMAN	Laforin	9931343	A novel protein tyrosine phosphatase gene is mutated in progressive myoclonus epilepsy of the Lafora type (EPM2).

Q96EG1	ARSG_HUMAN	Arylsulfatase G	12461688	Molecular and biochemical characterisation of a novel sulphatase gene: arylsulfatase G (ARSG).

Q9SGW3	RP12A_ARATH	26S proteasome non-ATPase regulatory subunit RPN12A	17971041	26S proteasome regulatory particle mutants have increased oxidative stress tolerance.

P46844	BIEA_RAT	Biliverdin reductase A	1371282	Expression and characterization of a cDNA for rat kidney biliverdin reductase. Evidence suggesting the liver and kidney enzymes are the same transcript product.

Q99NH0	ANR17_MOUSE	Ankyrin repeat domain-containing protein 17	11165478	A gene trap integration provides an early in situ marker for hepatic specification of the foregut endoderm.

Q08673	SRL1_YEAST	Cell wall protein SRL1	14562095	Global analysis of protein localization in budding yeast.

Q9P7M0	YOS3_SCHPO	ABC1 family protein C21C3.03, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q5AU62	NMRA_EMENI	Nitrogen metabolite repression protein nmrA	11726498	The structure of the negative transcriptional regulator NmrA reveals a structural superfamily which includes the short-chain dehydrogenase/reductases.

P05771	KPCB_HUMAN	Protein kinase C beta type	20228790	Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4.

O59732	CHR1_SCHPO	Chitin synthase regulatory factor 1	15449309	Chr4, a Schizosaccharomyces pombe homologue of the Saccharomyces cerevisiae Chs4p/Skt5p protein, is related to septum formation and is required for the proper localization of Chs2.

O22476	BRI1_ARATH	Protein BRASSINOSTEROID INSENSITIVE 1	15319482	The Arabidopsis transthyretin-like protein is a potential substrate of BRASSINOSTEROID-INSENSITIVE 1.

P49620	DGKG_RAT	Diacylglycerol kinase gamma	7809169	Cloning and expression of a cytoskeleton-associated diacylglycerol kinase that is dominantly expressed in cerebellum.

P08754	GNAI3_HUMAN	Guanine nucleotide-binding protein G(k) subunit alpha	3109953	Molecular cloning of a new human G protein. Evidence for two Gi alpha-like protein families.

P24310	CX7A1_HUMAN	Cytochrome c oxidase subunit 7A1, mitochondrial	9344674	Genomic sequence and organization of the human gene for cytochrome c oxidase subunit (COX7A1) VIIa-M.

Q9D666	SUN1_MOUSE	SUN domain-containing protein 1	12036294	Identification and characterization of cDNAs encoding four novel proteins that interact with translin associated factor-X.

Q27913	GBP_PSESE	Growth-blocking peptide, long form	12182821	Expression and purification of a small cytokine growth-blocking peptide from armyworm Pseudaletia separata by an optimized fermentation method using the methylotrophic yeast Pichia pastoris.

Q9XWD6	CED1_CAEEL	Cell death abnormality protein 1	6857247	Mutations affecting programmed cell deaths in the nematode Caenorhabditis elegans.

P47709	RP3A_RAT	Rabphilin-3A	7946335	Synaptic targeting of rabphilin-3A, a synaptic vesicle Ca2+/phospholipid-binding protein, depends on rab3A/3C.

Q9XHE7	C71DD_MENPI	Cytochrome P450 71D13	10415126	Regiospecific cytochrome P450 limonene hydroxylases from mint (Mentha) species: cDNA isolation, characterization, and functional expression of (-)-4S-limonene-3-hydroxylase and (-)-4S-limonene-6- hydroxylase.

O75474	FRAT2_HUMAN	GSK-3-binding protein FRAT2	9635432	GBP, an inhibitor of GSK-3, is implicated in Xenopus development and oncogenesis.

P48059	LIMS1_HUMAN	LIM and senescent cell antigen-like-containing domain protein 1	7517666	A new LIM protein containing an autoepitope homologous to 'senescent cell antigen'.

P39551	PRM9_YEAST	Pheromone-regulated membrane protein 9	12101299	Functional analysis of the Saccharomyces cerevisiae DUP240 multigene family reveals membrane-associated proteins that are not essential for cell viability.

P38827	SET1_YEAST	Histone-lysine N-methyltransferase, H3 lysine-4 specific	11752412	A trithorax-group complex purified from Saccharomyces cerevisiae is required for methylation of histone H3.

Q04264	PDS5_YEAST	Sister chromatid cohesion protein PDS5	11062262	Pds5p is an essential chromosomal protein required for both sister chromatid cohesion and condensation in Saccharomyces cerevisiae.

Q9Y6K1	DNM3A_HUMAN	DNA (cytosine-5)-methyltransferase 3A	17713477	Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation.

Q13188	STK3_HUMAN	Serine/threonine-protein kinase 3	8566796	Cloning and characterization of a member of the MST subfamily of Ste20-like kinases.

P36775	LONM_YEAST	Lon protease homolog, mitochondrial	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Q9FI23	DEF16_ARATH	Defensin-like protein 16	8989885	Pathogen-induced systemic activation of a plant defensin gene in Arabidopsis follows a salicylic acid-independent pathway.

Q64467	G3PT_MOUSE	Glyceraldehyde-3-phosphate dehydrogenase, testis-specific	15546993	Glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme, is required for sperm motility and male fertility.

O59676	PDP1_SCHPO	PWWP domain-containing protein 1	19250904	Regulation of Set9-mediated H4K20 methylation by a PWWP domain protein.

Q93ZG7	RH38_ARATH	DEAD-box ATP-dependent RNA helicase 38	12165572	RNA helicase-like protein as an early regulator of transcription factors for plant chilling and freezing tolerance.

P06730	IF4E_HUMAN	Eukaryotic translation initiation factor 4E	10856257	A novel shuttling protein, 4E-T, mediates the nuclear import of the mRNA 5' cap-binding protein, eIF4E.

P57094	AXN1_DANRE	Axin-1	10704853	Cooperative roles of Bozozok/Dharma and Nodal-related proteins in the formation of the dorsal organizer in zebrafish.

Q9FMF4	SAC51_ARATH	Transcription factor SAC51	16936072	The dwarf phenotype of the Arabidopsis acl5 mutant is suppressed by a mutation in an upstream ORF of a bHLH gene.

Q9UHD2	TBK1_HUMAN	Serine/threonine-protein kinase TBK1	14530355	Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3, in the Toll-like receptor signaling.

P43558	OTU1_YEAST	Ubiquitin thioesterase OTU1	15755922	Genomic analysis of PIS1 gene expression.

O59668	YB83_SCHPO	LisH domain-containing protein C29A3.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P19338	NUCL_HUMAN	Nucleolin	2737305	Cloning and sequencing of the human nucleolin cDNA.

Q96RT7	GCP6_HUMAN	Gamma-tubulin complex component 6	11694571	GCP5 and GCP6: two new members of the human gamma-tubulin complex.

Q9IB89	ZIC5_XENLA	Zinc finger protein ZIC 5	11091076	A novel member of the Xenopus Zic family, Zic5, mediates neural crest development.

Q14031	CO4A6_HUMAN	Collagen alpha-6(IV) chain	8125972	Identification of a new collagen IV chain, alpha 6(IV), by cDNA isolation and assignment of the gene to chromosome Xq22, which is the same locus for COL4A5.

P41595	5HT2B_HUMAN	5-hydroxytryptamine receptor 2B	7926008	The human serotonin 5-HT2B receptor: pharmacological link between 5- HT2 and 5-HT1D receptors.

P53935	NST1_YEAST	Stress response protein NST1	14562095	Global analysis of protein localization in budding yeast.

P40559	INP51_YEAST	Inositol-1,4,5-trisphosphate 5-phosphatase 1	15265867	Negative regulation of phosphatidylinositol 4,5-bisphosphate levels by the INP51-associated proteins TAX4 and IRS4.

P92983	PROD1_ARATH	Proline dehydrogenase 1, mitochondrial	8776899	A nuclear gene encoding mitochondrial proline dehydrogenase, an enzyme involved in proline metabolism, is upregulated by proline but downregulated by dehydration in Arabidopsis.

P0AEH1	RSEP_ECOLI	Regulator of sigma E protease	11867724	Rapid topology mapping of Escherichia coli inner-membrane proteins by prediction and PhoA/GFP fusion analysis.

P21741	MK_HUMAN	Midkine	9384573	Solution structure of midkine, a new heparin-binding growth factor.

Q9UM54	MYO6_HUMAN	Myosin-VI	10519557	Myosin VI is an actin-based motor that moves backwards.

Q9C107	MCL1_SCHPO	Minichromosome loss protein 1	15915339	Genetic and physical interactions between Schizosaccharomyces pombe Mcl1 and Rad2, Dna2 and DNA polymerase alpha: evidence for a multifunctional role of Mcl1 in DNA replication and repair.

O02100	HOP1_CAEEL	Presenilin hop-1	10051671	Reverse genetic analysis of Caenorhabditis elegans presenilins reveals redundant but unequal roles for sel-12 and hop-1 in Notch- pathway signaling.

P30822	XPO1_YEAST	Exportin-1	9323132	Exportin 1 (Crm1p) is an essential nuclear export factor.

O14756	H17B6_HUMAN	17-beta-hydroxysteroid dehydrogenase type 6	11513953	Gene structure, chromosomal localization and analysis of 3- ketosteroid reductase activity of the human 3(alpha-->beta)- hydroxysteroid epimerase.

Q05793	PGBM_MOUSE	Basement membrane-specific heparan sulfate proteoglycan core protein	10545953	Perlecan is essential for cartilage and cephalic development.

Q5I0E9	S47A1_RAT	Multidrug and toxin extrusion protein 1	16928787	Molecular identification and functional characterization of rat multidrug and toxin extrusion type transporter 1 as an organic cation/H+ antiporter in the kidney.

P25024	CXCR1_HUMAN	C-X-C chemokine receptor type 1	1840701	Structure and functional expression of a human interleukin-8 receptor.

P09564	CD7_HUMAN	T-cell antigen CD7	3501369	Molecular cloning of two CD7 (T-cell leukemia antigen) cDNAs by a COS cell expression system.

Q91V82	DEFB8_MOUSE	Beta-defensin 8	12226710	Identification and characterisation a novel murine beta defensin related gene.

Q53GA4	PHLA2_HUMAN	Pleckstrin homology-like domain family A member 2	9328465	The IPL gene on chromosome 11p15.5 is imprinted in humans and mice and is similar to TDAG51, implicated in Fas expression and apoptosis.

Q54WN5	UTP6_DICDI	U3 small nucleolar RNA-associated protein 6 homolog	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

Q9Z1Z2	STRAP_MOUSE	Serine-threonine kinase receptor-associated protein	9856985	Identification of STRAP, a novel WD domain protein in transforming growth factor-beta signaling.

Q14576	ELAV3_HUMAN	ELAV-like protein 3	10710437	RNA-binding analyses of HuC and HuD with the VEGF and c-myc 3'- untranslated regions using a novel ELISA-based assay.

O00541	PESC_HUMAN	Pescadillo homolog	17353269	Interdependence of Pes1, Bop1, and WDR12 controls nucleolar localization and assembly of the PeBoW complex required for maturation of the 60S ribosomal subunit.

P25364	HCM1_YEAST	Forkhead transcription factor HCM1	9920414	The fork head transcription factor Hcm1p participates in the regulation of SPC110, which encodes the calmodulin-binding protein in the yeast spindle pole body.

O00308	WWP2_HUMAN	NEDD4-like E3 ubiquitin-protein ligase WWP2	19651900	The HECT-type E3 ubiquitin ligase AIP2 inhibits activation-induced T- cell death by catalyzing EGR2 ubiquitination.

P53875	RM19_YEAST	54S ribosomal protein L19, mitochondrial	9151978	Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae.

Q01887	RYK_MOUSE	Tyrosine-protein kinase RYK	1334548	RYK, a receptor tyrosine kinase-related molecule with unusual kinase domain motifs.

O22609	DEGP1_ARATH	Protease Do-like 1, chloroplastic	11719511	Proteome map of the chloroplast lumen of Arabidopsis thaliana.

P63144	KCAB1_RAT	Voltage-gated potassium channel subunit beta-1	16504945	The epilepsy-linked Lgi1 protein assembles into presynaptic Kv1 channels and inhibits inactivation by Kvbeta1.

Q7TNZ6	STRAA_RAT	STE20-related kinase adapter protein alpha	14511394	Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade.

Q3E7B7	YD85C_YEAST	SERF-like protein YDL085C-A	14562095	Global analysis of protein localization in budding yeast.

P36412	RB11A_DICDI	Ras-related protein Rab-11A	11686306	Rab11-like GTPase associates with and regulates the structure and function of the contractile vacuole system in dictyostelium.

Q8NB46	ANR52_HUMAN	Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C	18186651	Protein phosphatase 6 regulatory subunits composed of ankyrin repeat domains.

P29460	IL12B_HUMAN	Interleukin-12 subunit beta	1673147	Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells.

Q9NRV9	HEBP1_HUMAN	Heme-binding protein 1	10640688	Discovery of a putative heme-binding protein family (SOUL/HBP) by two-tissue suppression subtractive hybridization and database searches.

P08476	INHBA_HUMAN	Inhibin beta A chain	12697670	Differential binding and neutralization of activins A and B by follistatin and follistatin like-3 (FSTL-3/FSRP/FLRG).

P84214	BOMB_BOMBO	Bombesin	4537042	Isolation and amino acid sequences of alytesin and bombesin, two analogous active tetradecapeptides from the skin of European discoglossid frogs.

O48646	GPX6_ARATH	Probable phospholipid hydroperoxide glutathione peroxidase 6, mitochondrial	14617062	Glutathione peroxidase genes in Arabidopsis are ubiquitous and regulated by abiotic stresses through diverse signaling pathways.

Q9NPI1	BRD7_HUMAN	Bromodomain-containing protein 7	11025449	Molecular characterization of celtix-1, a bromodomain protein interacting with the transcription factor interferon regulatory factor 2.

Q9QZE2	CLNK_MOUSE	Cytokine-dependent hematopoietic cell linker	10562326	Clnk, a novel SLP-76-related adaptor molecule expressed in cytokine- stimulated hemopoietic cells.

P19957	ELAF_HUMAN	Elafin	2394696	Elafin: an elastase-specific inhibitor of human skin. Purification, characterization, and complete amino acid sequence.

P38629	RFC3_YEAST	Replication factor C subunit 3	7651383	Characterization of the five replication factor C genes of Saccharomyces cerevisiae.

Q9M7Q2	AI5L7_ARATH	ABSCISIC ACID-INSENSITIVE 5-like protein 7	10636868	ABFs, a family of ABA-responsive element binding factors.

P39516	RS14B_YEAST	40S ribosomal protein S14-B	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

P10067	CRGD_RAT	Gamma-crystallin D	7849105	High level expression of rat gamma-D-crystallin in Escherichia coli.

Q9UHI5	LAT2_HUMAN	Large neutral amino acids transporter small subunit 2	10574970	LAT2, a new basolateral 4F2hc/CD98-associated amino acid transporter of kidney and intestine.

Q05215	EGR4_HUMAN	Early growth response protein 4	1658795	Clone pAT133 identifies a gene that encodes another human member of a class of growth factor-induced genes with almost identical zinc-finger domains.

O57686	SMO1A_XENLA	Small ubiquitin-related modifier 1-A	16256735	SoxE factors function equivalently during neural crest and inner ear development and their activity is regulated by SUMOylation.

Q9UBQ6	EXTL2_HUMAN	Exostosin-like 2	10318803	The tumor suppressor EXT-like gene EXTL2 encodes an alpha1, 4-N- acetylhexosaminyltransferase that transfers N-acetylgalactosamine and N-acetylglucosamine to the common glycosaminoglycan-protein linkage region. The key enzyme for the chain initiation of heparan sulfate.

O88664	TAOK1_RAT	Serine/threonine-protein kinase TAO1	9786855	Isolation of TAO1, a protein kinase that activates MEKs in stress- activated protein kinase cascades.

P53619	COPD_BOVIN	Coatomer subunit delta	8858162	Architecture of coatomer: molecular characterization of delta-COP and protein interactions within the complex.

P15442	GCN2_YEAST	Serine/threonine-protein kinase GCN2	2038314	Ribosome association of GCN2 protein kinase, a translational activator of the GCN4 gene of Saccharomyces cerevisiae.

P49893	WN11B_XENLA	Protein Wnt-11b	10769246	Xwnt11 is a target of Xenopus Brachyury: regulation of gastrulation movements via Dishevelled, but not through the canonical Wnt pathway.

P18564	ITB6_HUMAN	Integrin beta-6	2365683	Complete amino acid sequence of a novel integrin beta subunit (beta 6) identified in epithelial cells using the polymerase chain reaction.

Q96DC9	OTUB2_HUMAN	Ubiquitin thioesterase OTUB2	12704427	Otubains: a new family of cysteine proteases in the ubiquitin pathway.

P38319	TYDP1_YEAST	Tyrosyl-DNA phosphodiesterase 1	16751265	Tyrosyl-DNA phosphodiesterase (Tdp1) participates in the repair of Top2-mediated DNA damage.

Q9NZI8	IF2B1_HUMAN	Insulin-like growth factor 2 mRNA-binding protein 1	9891060	A family of insulin-like growth factor II mRNA-binding proteins represses translation in late development.

P48421	C83A1_ARATH	Cytochrome P450 83A1	12970475	CYP83A1 and CYP83B1, two nonredundant cytochrome P450 enzymes metabolizing oximes in the biosynthesis of glucosinolates in Arabidopsis.

P35348	ADA1A_HUMAN	Alpha-1A adrenergic receptor	8183249	The alpha 1-adrenergic receptor that mediates smooth muscle contraction in human prostate has the pharmacological properties of the cloned human alpha 1c subtype.

P0ABQ0	COABC_ECOLI	Coenzyme A biosynthesis bifunctional protein CoaBC	10922366	Molecular characterization of lantibiotic-synthesizing enzyme EpiD reveals a function for bacterial Dfp proteins in coenzyme A biosynthesis.

Q13686	ALKB1_HUMAN	Alkylated DNA repair protein alkB homolog 1	19959401	Human AlkB homologue 1 (ABH1) exhibits DNA lyase activity at abasic sites.

P25153	UBCD6_DROME	Ubiquitin-conjugating enzyme E2-17 kDa	1902572	Dhr6, a Drosophila homolog of the yeast DNA-repair gene RAD6.

P00374	DYR_HUMAN	Dihydrofolate reductase	6687716	The nucleotide sequence of the cDNA coding for the human dihydrofolic acid reductase.

O00300	TR11B_HUMAN	Tumor necrosis factor receptor superfamily member 11B	9168977	Isolation of a novel cytokine from human fibroblasts that specifically inhibits osteoclastogenesis.

P54661	SMLA_DICDI	Small aggregate formation protein	8787732	A Dictystelium mutant with defective aggregate size determination.

P34259	SDZ1_CAEEL	Skn-1 dependent zygotic transcript 1 protein	15737937	The noncanonical binding site of the MED-1 GATA factor defines differentially regulated target genes in the C. elegans mesendoderm.

Q6P2E9	EDC4_HUMAN	Enhancer of mRNA-decapping protein 4	16364915	Multiple processing body factors and the ARE binding protein TTP activate mRNA decapping.

P38418	LOX2_ARATH	Lipoxygenase 2, chloroplastic	11117257	Plant lipoxygenase 2 is a translation initiation factor-4E-binding protein.

P62266	RS23_HUMAN	40S ribosomal protein S23	8415000	A cDNA sequence of human ribosomal protein, homologue of yeast S28.

Q54HC6	ARKA_DICDI	Ankyrin repeat-containing protein kinase A	14597204	The novel ankyrin-repeat containing kinase ARCK-1 acts as a suppressor of the Spalten signaling pathway during Dictyostelium development.

Q04636	POB3_YEAST	FACT complex subunit POB3	15987999	The yeast FACT complex has a role in transcriptional initiation.

Q8S9K3	VAR3_ARATH	Zinc finger protein VAR3, chloroplastic	15340011	Arabidopsis VARIEGATED 3 encodes a chloroplast-targeted, zinc-finger protein required for chloroplast and palisade cell development.

Q9C5Y2	KAO2_ARATH	Ent-kaurenoic acid oxidase 2	11722763	A plastid envelope location of Arabidopsis ent-kaurene oxidase links the plastid and endoplasmic reticulum steps of the gibberellin biosynthesis pathway.

P31554	LPTD_ECOLI	LPS-assembly protein lptD	12207697	Imp/OstA is required for cell envelope biogenesis in Escherichia coli.

Q9JKT7	T2R13_RAT	Taste receptor type 2 member 13	10761934	A novel family of mammalian taste receptors.

O59808	BADH_SCHPO	Probable betaine aldehyde dehydrogenase	11376151	Comprehensive isolation of meiosis-specific genes identifies novel proteins and unusual non-coding transcripts in Schizosaccharomyces pombe.

Q39649	2SS_CUCMA	2S albumin	8275099	Vesicle transport and processing of the precursor to 2S albumin in pumpkin.

P33667	SELU_ECOLI	tRNA 2-selenouridine synthase	14594807	Functional diversity of the rhodanese homology domain: the Escherichia coli ybbB gene encodes a selenophosphate-dependent tRNA 2- selenouridine synthase.

Q680Q4	SIZ1_ARATH	E3 SUMO-protein ligase SIZ1	17163880	Salicylic acid-mediated innate immunity in Arabidopsis is regulated by SIZ1 SUMO E3 ligase.

Q9UMS0	NFU1_HUMAN	NFU1 iron-sulfur cluster scaffold homolog, mitochondrial	12915448	The Lafora disease gene product laforin interacts with HIRIP5, a phylogenetically conserved protein containing a NifU-like domain.

Q5K4E3	POLS2_HUMAN	Polyserase-2	15536082	Human polyserase-2, a novel enzyme with three tandem serine protease domains in a single polypeptide chain.

P04207	KV308_HUMAN	Ig kappa chain V-III region CLL	3083417	Cloning and sequence determination of a human rheumatoid factor light-chain gene.

Q06143	DIC1_YEAST	Mitochondrial dicarboxylate transporter	15591051	The carboxyl-terminal third of the dicarboxylate carrier is crucial for productive association with the inner membrane twin-pore translocase.

A0MZ67	SHOT1_RAT	Shootin-1	17439943	Singar1, a novel RUN domain-containing protein, suppresses formation of surplus axons for neuronal polarity.

P38856	AP18A_YEAST	Clathrin coat assembly protein AP180A	9531549	Pan1p, yeast eps15, functions as a multivalent adaptor that coordinates protein-protein interactions essential for endocytosis.

Q53HL2	BOREA_HUMAN	Borealin	18591255	A survivin-ran complex regulates spindle formation in tumor cells.

Q04721	NOTC2_HUMAN	Neurogenic locus notch homolog protein 2	1303260	Human homologs of a Drosophila enhancer of split gene product define a novel family of nuclear proteins.

P87139	YDM9_SCHPO	Uncharacterized RING finger protein C57A7.09	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q07500	NDH2_YEAST	External NADH-ubiquinone oxidoreductase 2, mitochondrial	12032156	Kinetic regulation of the mitochondrial glycerol-3-phosphate dehydrogenase by the external NADH dehydrogenase in Saccharomyces cerevisiae.

Q17551	RPM1_CAEEL	E3 ubiquitin-protein ligase rpm-1	10839353	Regulation of presynaptic terminal organization by C. elegans RPM-1, a putative guanine nucleotide exchanger with a RING-H2 finger domain.

O08579	EMD_MOUSE	Emerin	19933576	Mammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processes.

Q16563	SYPL1_HUMAN	Synaptophysin-like protein 1	8034131	Expression of the synaptophysin gene family is not restricted to neuronal and neuroendocrine differentiation in rat and human.

P18163	ACSL1_RAT	Long-chain-fatty-acid--CoA ligase 1	2341402	Structure and regulation of rat long-chain acyl-CoA synthetase.

P41376	IF4A1_ARATH	Eukaryotic initiation factor 4A-1	14706832	In vivo interaction between CDKA and eIF4A: a possible mechanism linking translation and cell proliferation.

Q9XUS2	MED29_CAEEL	Mediator of RNA polymerase II transcription subunit 29	15020414	sel-7, a positive regulator of lin-12 activity, encodes a novel nuclear protein in Caenorhabditis elegans.

Q63673	SHH_RAT	Sonic hedgehog protein	8124714	Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord.

Q6T393	SPT20_RAT	Spermatogenesis-associated protein 20	15223837	Cloning and characterization of rat spermatid protein SSP411: a thioredoxin-like protein.

P32897	TIM23_YEAST	Mitochondrial import inner membrane translocase subunit TIM23	15797382	Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17.

Q9ULZ1	APEL_HUMAN	Apelin	9792798	Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor.

Q9U539	OCT1_CAEEL	Organic cation transporter 1	10209228	Identity of the F52F12.1 gene product in Caenorhabditis elegans as an organic cation transporter.

O74786	SEC9_SCHPO	Protein transport protein sec9	16272747	A fission yeast SNAP-25 homologue, SpSec9, is essential for cytokinesis and sporulation.

Q08985	SAM4_YEAST	Homocysteine S-methyltransferase 2	14562095	Global analysis of protein localization in budding yeast.

P70196	TRAF6_MOUSE	TNF receptor-associated factor 6	8910514	Identification of TRAF6, a novel tumor necrosis factor receptor- associated factor protein that mediates signaling from an amino- terminal domain of the CD40 cytoplasmic region.

O14910	LIN7A_HUMAN	Protein lin-7 homolog A	11311936	VAM-1: a new member of the MAGUK family binds to human Veli-1 through a conserved domain.

Q8N4Y2	EFC4A_HUMAN	EF-hand calcium-binding domain-containing protein 4A	20418871	A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cells.

Q52K88	NUD13_ARATH	Nudix hydrolase 13, mitochondrial	18815383	Molecular characterization of organelle-type Nudix hydrolases in Arabidopsis.

P35401	CRAC_DICDI	Protein CRAC	8089184	CRAC, a cytosolic protein containing a pleckstrin homology domain, is required for receptor and G protein-mediated activation of adenylyl cyclase in Dictyostelium.

Q9P332	YLZ4_SCHPO	UPF0742 protein C750.04c/C977.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O60132	TEA4_SCHPO	Tip elongation aberrant protein Tea4	15809031	Tea4p links microtubule plus ends with the formin for3p in the establishment of cell polarity.

P53953	SFB2_YEAST	SED5-binding protein 2	10712514	Sec24p and Iss1p function interchangeably in transport vesicle formation from the endoplasmic reticulum in Saccharomyces cerevisiae.

Q9UNE7	CHIP_HUMAN	E3 ubiquitin-protein ligase CHIP	18042044	Two different classes of E2 ubiquitin-conjugating enzymes are required for the mono-ubiquitination of proteins and elongation by polyubiquitin chains with a specific topology.

P49888	ST1E1_HUMAN	Estrogen sulfotransferase	7779757	Bacterial expression and characterization of a cDNA for human liver estrogen sulfotransferase.

Q24423	NOC_DROME	Zinc finger protein Noc	14757638	Proximodistal subdivision of Drosophila legs and wings: the elbow-no ocelli gene complex.

B2RX14	TUT4_MOUSE	Terminal uridylyltransferase 4	19701194	Zcchc11-dependent uridylation of microRNA directs cytokine expression.

Q63664	IRK8_RAT	ATP-sensitive inward rectifier potassium channel 8	7890693	Cloning and functional characterization of a novel ATP-sensitive potassium channel ubiquitously expressed in rat tissues, including pancreatic islets, pituitary, skeletal muscle, and heart.

P51142	DVL2_XENLA	Segment polarity protein dishevelled homolog DVL-2	10811222	Dishevelled controls cell polarity during Xenopus gastrulation.

Q13424	SNTA1_HUMAN	Alpha-1-syntrophin	8576247	The three human syntrophin genes are expressed in diverse tissues, have distinct chromosomal locations, and each bind to dystrophin and its relatives.

Q9PVZ3	FXC1A_XENLA	Forkhead box protein C1-A	9767159	Expression pattern of the winged helix factor XFD-11 during Xenopus embryogenesis.

P06756	ITAV_HUMAN	Integrin alpha-V	17925226	Rab25 associates with alpha5beta1 integrin to promote invasive migration in 3D microenvironments.

Q8CGB3	UACA_MOUSE	Uveal autoantigen with coiled-coil domains and ankyrin repeats	15271982	Nucling recruits Apaf-1/pro-caspase-9 complex for the induction of stress-induced apoptosis.

Q9GSX9	RIC8_CAEEL	Synembryn	15498497	Control of embryonic spindle positioning and Galpha activity by C. elegans RIC-8.

Q14183	DOC2A_HUMAN	Double C2-like domain-containing protein alpha	7826360	Doc2, a novel synaptic vesicle protein with two repeated C2-like domains.

P30557	PE2R3_MOUSE	Prostaglandin E2 receptor EP3 subtype	8381413	Two isoforms of the EP3 receptor with different carboxyl-terminal domains. Identical ligand binding properties and different coupling properties with Gi proteins.

Q9JM52	MINK1_MOUSE	Misshapen-like kinase 1	10708748	Molecular cloning of MINK, a novel member of mammalian GCK family kinases, which is up-regulated during postnatal mouse cerebral development.

Q9CAV6	WNK1_ARATH	Serine/threonine-protein kinase WNK1	12091722	The APRR3 component of the clock-associated APRR1/TOC1 quintet is phosphorylated by a novel protein kinase belonging to the WNK family, the gene for which is also transcribed rhythmically in Arabidopsis thaliana.

Q3UW12	CNGA4_MOUSE	Cyclic nucleotide-gated cation channel alpha-4	11739959	Central role of the CNGA4 channel subunit in Ca2+-calmodulin- dependent odor adaptation.

O74689	NDE1_EMENI	Nuclear distribution protein nudE	10931877	The LIS1-related NUDF protein of Aspergillus nidulans interacts with the coiled-coil domain of the NUDE/RO11 protein.

O95294	RASL1_HUMAN	RasGAP-activating-like protein 1	9751798	Restricted tissue expression pattern of a novel human rasGAP-related gene and its murine ortholog.

Q9S1E5	NRFA_WOLSU	Cytochrome c-552	10672190	A NapC/NirT-type cytochrome c (NrfH) is the mediator between the quinone pool and the cytochrome c nitrite reductase of Wolinella succinogenes.

O14348	NC2B_SCHPO	Negative cofactor 2 complex subunit beta	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q42525	HXK1_ARATH	Hexokinase-1	16920781	Mitochondria-associated hexokinases play a role in the control of programmed cell death in Nicotiana benthamiana.

Q10432	CCQ1_SCHPO	Coiled-coil quantitatively-enriched protein 1	15546621	An SMC-domain protein in fission yeast links telomeres to the meiotic centrosome.

O14646	CHD1_HUMAN	Chromodomain-helicase-DNA-binding protein 1	9326634	Characterization of the CHD family of proteins.

P50526	SSP1_SCHPO	Serine/threonine-protein kinase ssp1	7628434	A novel protein kinase gene ssp1+ is required for alteration of growth polarity and actin localization in fission yeast.

O59672	YB89_SCHPO	Uncharacterized ABC transporter ATP-binding protein C29A3.09c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q86B61	TBH1_DROME	Tyramine beta-hydroxylase	8656284	Characterization of Drosophila tyramine beta-hydroxylase gene and isolation of mutant flies lacking octopamine.

Q969L4	LSM10_HUMAN	U7 snRNA-associated Sm-like protein LSm10	11574479	Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein.

Q9C5X3	KEULE_ARATH	SNARE-interacting protein KEULE	11157980	The cytokinesis gene KEULE encodes a Sec1 protein that binds the syntaxin KNOLLE.

P38333	ENP1_YEAST	Essential nuclear protein 1	9034325	ENP1, an essential gene encoding a nuclear protein that is highly conserved from yeast to humans.

P84645	PALIC_PALCO	Palicourein	11430013	A novel anti-HIV macrocyclic peptide from Palicourea condensata.

Q8BVM4	ADC_MOUSE	Antizyme inhibitor 2	16916800	Mouse ornithine decarboxylase-like gene encodes an antizyme inhibitor devoid of ornithine and arginine decarboxylating activity.

Q8CGR3	CS2LB_RAT	Alpha-S2-casein-like B	13679022	Multispecies comparative analysis of a mammalian-specific genomic domain encoding secretory proteins.

Q00869	ESYN_FUSEQ	Enniatin synthase	10887181	Mutational analysis of the N-methyltransferase domain of the multifunctional enzyme enniatin synthetase.

P60519	GBRL2_BOVIN	Gamma-aminobutyric acid receptor-associated protein-like 2	10747018	GATE-16, a membrane transport modulator, interacts with NSF and the Golgi v-SNARE GOS-28.

Q13561	DCTN2_HUMAN	Dynactin subunit 2	10226031	The APC-associated protein EB1 associates with components of the dynactin complex and cytoplasmic dynein intermediate chain.

A2APF3	CTCFL_MOUSE	Transcriptional repressor CTCFL	12011441	BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma.

Q91876	MCM7A_XENLA	DNA replication licensing factor mcm7-A	9851868	Evidence for different MCM subcomplexes with differential binding to chromatin in Xenopus.

Q9AYP9	LECC_PHYAM	Lectin-C	7772833	Purification and characterization of three mitogenic lectins from the roots of pokeweed (Phytolacca americana).

P22812	TUBE_DROME	Protein Tube	10512628	Formation and biochemical characterization of tube/pelle death domain complexes: critical regulators of postreceptor signaling by the Drosophila toll receptor.

Q10336	MCP6_SCHPO	Meiotic coiled-coil protein 6	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8MSS1	LVA_DROME	Protein lava lamp	11076973	Lava lamp, a novel peripheral Golgi protein, is required for Drosophila melanogaster cellularization.

Q9P2M1	LR2BP_HUMAN	LRP2-binding protein	12508107	Functional interaction of megalin with the megalin-binding protein (MegBP), a novel tetratrico peptide repeat-containing adaptor molecule.

O74986	COM1_SCHPO	DNA endonuclease ctp1	18378696	Molecular characterization of the role of the Schizosaccharomyces pombe nip1+/ctp1+ gene in DNA double-strand break repair in association with the Mre11-Rad50-Nbs1 complex.

Q38846	ERS1_ARATH	Ethylene response sensor 1	7569898	Ethylene insensitivity conferred by Arabidopsis ERS gene.

Q12082	YD157_YEAST	Uncharacterized protein YDL157C, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q9P790	VPS72_SCHPO	SWR complex protein 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P82176	IMPI_GALME	Inducible metalloproteinase inhibitor protein	9738891	Purification and characterization of an inducible metalloprotease inhibitor from the hemolymph of greater wax moth larvae, Galleria mellonella.

O88397	SO1A5_RAT	Solute carrier organic anion transporter family member 1A5	11093941	Expression, transport properties, and chromosomal location of organic anion transporter subtype 3.

Q96S44	PRPK_HUMAN	TP53-regulating kinase	12659830	Identification of CGI-121, a novel PRPK (p53-related protein kinase)- binding protein.

Q62083	PICK1_MOUSE	PRKCA-binding protein	9883737	PDZ proteins bind, cluster, and synaptically colocalize with Eph receptors and their ephrin ligands.

Q99683	M3K5_HUMAN	Mitogen-activated protein kinase kinase kinase 5	11920685	Activation of apoptosis signal-regulating kinase 1 by the stress- induced activating phosphorylation of pre-formed oligomer.

Q91W90	TXND5_MOUSE	Thioredoxin domain-containing protein 5	12930873	ERp19 and ERp46, new members of the thioredoxin family of endoplasmic reticulum proteins.

Q8MSU3	FRRS1_DROME	Putative ferric-chelate reductase 1 homolog	14499595	Stromal cell-derived receptor 2 and cytochrome b561 are functional ferric reductases.

P40535	ACA2_YEAST	ATF/CREB activator 2	10454593	New yeast genes important for chromosome integrity and segregation identified by dosage effects on genome stability.

Q9Z0P7	SUFU_MOUSE	Suppressor of fused homolog	10531011	Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1.

P15086	CBPB1_HUMAN	Carboxypeptidase B	1370825	Isolation of a cDNA encoding a human serum marker for acute pancreatitis. Identification of pancreas-specific protein as pancreatic procarboxypeptidase B.

Q9UKL3	C8AP2_HUMAN	CASP8-associated protein 2	15698540	FLASH interacts with p160 coactivator subtypes and differentially suppresses transcriptional activity of steroid hormone receptors.

Q64151	SEM4C_MOUSE	Semaphorin-4C	17498836	Sema4C participates in myogenic differentiation in vivo and in vitro through the p38 MAPK pathway.

Q9NZ08	ERAP1_HUMAN	Endoplasmic reticulum aminopeptidase 1	10220586	Molecular cloning of adipocyte-derived leucine aminopeptidase highly related to placental leucine aminopeptidase/oxytocinase.

O94724	YCFC_SCHPO	Uncharacterized protein C1393.12	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Z282	GP132_MOUSE	Probable G-protein coupled receptor 132	9770487	A DNA damage and stress inducible G protein-coupled receptor blocks cells in G2/M.

Q01518	CAP1_HUMAN	Adenylyl cyclase-associated protein 1	1406678	Identification of a human cDNA encoding a protein that is structurally and functionally related to the yeast adenylyl cyclase- associated CAP proteins.

Q9H0D6	XRN2_HUMAN	5'-3' exoribonuclease 2	10409438	Cloning and mapping of the XRN2 gene to human chromosome 20p11.1- p11.2.

Q9LI74	CHUP1_ARATH	Protein CHUP1, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q92258	GRISA_PODAN	Protein GRISEA	12200031	Copper homeostasis and aging in the fungal model system Podospora anserina: differential expression of PaCtr3 encoding a copper transporter.

P36040	POC2_YEAST	Proteasome assembly chaperone 2	17634286	ADD66, a gene involved in the endoplasmic reticulum-associated degradation of alpha-1-antitrypsin-Z in yeast, facilitates proteasome activity and assembly.

P53860	PDR16_YEAST	Phosphatidylinositol transfer protein PDR16	9890948	PDR16 and PDR17, two homologous genes of Saccharomyces cerevisiae, affect lipid biosynthesis and resistance to multiple drugs.

O75690	KRA58_HUMAN	Keratin-associated protein 5-8	10023043	Genomic organization and promoter characterization of two human UHS keratin genes.

Q08729	DSE3_YEAST	Protein DSE3	14562095	Global analysis of protein localization in budding yeast.

O42650	RIO1_SCHPO	Serine/threonine-protein kinase rio1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P17157	PHO85_YEAST	Cyclin-dependent protein kinase PHO85	12407105	Pho85 phosphorylates the Glc7 protein phosphatase regulator Glc8 in vivo.

P35523	CLCN1_HUMAN	Chloride channel protein 1	1379744	The skeletal muscle chloride channel in dominant and recessive human myotonia.

Q02574	MEC3_YEAST	DNA damage checkpoint control protein MEC3	9988274	Interaction between Set1p and checkpoint protein Mec3p in DNA repair and telomere functions.

P35192	MAC1_YEAST	Metal-binding activator 1	12011036	Copper ion-sensing transcription factor Mac1p post-translationally controls the degradation of its target gene product Ctr1p.

P32354	MCM10_YEAST	Minichromosome maintenance protein 10	16675460	A conserved Hsp10-like domain in Mcm10 is required to stabilize the catalytic subunit of DNA polymerase-alpha in budding yeast.

P06401	PRGR_HUMAN	Progesterone receptor	17347654	CUE domain containing 2 regulates degradation of progesterone receptor by ubiquitin-proteasome.

Q960Z0	KI10A_DROME	Kinesin-like protein Klp10A	14681690	Two mitotic kinesins cooperate to drive sister chromatid separation during anaphase.

P01233	CGHB_HUMAN	Choriogonadotropin subunit beta	6194155	The beta subunit of human chorionic gonadotropin is encoded by multiple genes.

P48378	RFX2_HUMAN	DNA-binding protein RFX2	8289803	RFX1, a transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins.

Q9ZWD1	PR1G1_ARATH	PRA1 family protein G1	18583532	The PRA1 gene family in Arabidopsis.

Q7SIC0	HIS5_THET8	Imidazole glycerol phosphate synthase subunit hisH	12417026	Structure of imidazole glycerol phosphate synthase from Thermus thermophilus HB8: open-closed conformational change and ammonia tunneling.

P54132	BLM_HUMAN	Bloom syndrome protein	9388193	The Bloom's syndrome gene product is a 3'-5' DNA helicase.

P51028	WNT8A_DANRE	Protein Wnt-8a	11703928	Zebrafish wnt8 encodes two wnt8 proteins on a bicistronic transcript and is required for mesoderm and neurectoderm patterning.

P52657	T2AG_HUMAN	Transcription initiation factor IIA subunit 2	7724559	Human general transcription factor TFIIA: characterization of a cDNA encoding the small subunit and requirement for basal and activated transcription.

P63098	CANB1_HUMAN	Calcineurin subunit B type 1	8524402	Crystal structures of human calcineurin and the human FKBP12-FK506- calcineurin complex.

Q9UKT4	FBX5_HUMAN	F-box only protein 5	16921029	Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor.

Q03323	SDC1_YEAST	COMPASS component SDC1	11687631	COMPASS: a complex of proteins associated with a trithorax-related SET domain protein.

Q9BV57	MTND_HUMAN	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase	15938715	Membrane-type 1 matrix metalloproteinase cytoplasmic tail binding protein-1 (MTCBP-1) acts as an eukaryotic aci-reductone dioxygenase (ARD) in the methionine salvage pathway.

Q99677	LPAR4_HUMAN	Lysophosphatidic acid receptor 4	9073069	Cloning and chromosomal mapping of four putative novel human G- protein-coupled receptor genes.

Q13324	CRFR2_HUMAN	Corticotropin-releasing factor receptor 2	9717834	Molecular identification and analysis of a novel human corticotropin- releasing factor (CRF) receptor: the CRF2gamma receptor.

P33895	NUF2_YEAST	Kinetochore protein NUF2	8188751	Nuf2, a spindle pole body-associated protein required for nuclear division in yeast.

Q9Y7U6	RGF1_SCHPO	Rho1 guanine nucleotide exchange factor 1	16324155	Rho1-GEFs Rgf1 and Rgf2 are involved in formation of cell wall and septum, while Rgf3 is involved in cytokinesis in fission yeast.

P61604	CH10_HUMAN	10 kDa heat shock protein, mitochondrial	12483302	Genomic structure of the human mitochondrial chaperonin genes: HSP60 and HSP10 are localised head to head on chromosome 2 separated by a bidirectional promoter.

P49167	RL38_YEAST	60S ribosomal protein L38	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

O14019	HAL4_SCHPO	Serine/threonine-protein kinase hal4	15870269	Response of fission yeast to toxic cations involves cooperative action of the stress-activated protein kinase Spc1/Sty1 and the Hal4 protein kinase.

Q9P7V5	SEC7B_SCHPO	Protein transport protein sec72	18257517	Phosphoproteome analysis of fission yeast.

Q96G91	P2Y11_HUMAN	P2Y purinoceptor 11	9405388	Cloning of a human purinergic P2Y receptor coupled to phospholipase C and adenylyl cyclase.

O82200	MIOX2_ARATH	Inositol oxygenase 2	15660207	The inositol oxygenase gene family of Arabidopsis is involved in the biosynthesis of nucleotide sugar precursors for cell-wall matrix polysaccharides.

P38237	UBP14_YEAST	Ubiquitin carboxyl-terminal hydrolase 14	12686616	Catabolite degradation of fructose-1,6-bisphosphatase in the yeast Saccharomyces cerevisiae: a genome-wide screen identifies eight novel GID genes and indicates the existence of two degradation pathways.

Q06136	KDSR_HUMAN	3-ketodihydrosphingosine reductase	15328338	FVT-1 is a mammalian 3-ketodihydrosphingosine reductase with an active site that faces the cytosolic side of the endoplasmic reticulum membrane.

Q9UL17	TBX21_HUMAN	T-box transcription factor TBX21	10761931	A novel transcription factor, T-bet, directs Th1 lineage commitment.

Q94CG2	BET12_ARATH	Bet1-like SNARE 1-2	11445081	AtBS14a and AtBS14b, two Bet1/Sft1-like SNAREs from Arabidopsis thaliana that complement mutations in the yeast SFT1 gene.

Q9NZR1	TMOD2_HUMAN	Tropomodulin-2	10662549	Sequencing, expression analysis, and mapping of three unique human tropomodulin genes and their mouse orthologs.

P11655	SEC12_YEAST	Guanine nucleotide-exchange factor SEC12	3047151	A membrane glycoprotein, Sec12p, required for protein transport from the endoplasmic reticulum to the Golgi apparatus in yeast.

Q645N4	PAX3A_XENLA	Paired box protein Pax-3-A	17409353	The activity of Pax3 and Zic1 regulates three distinct cell fates at the neural plate border.

O00268	TAF4_HUMAN	Transcription initiation factor TFIID subunit 4	10373431	Identification of TATA-binding protein-free TAFII-containing complex subunits suggests a role in nucleosome acetylation and signal transduction.

O94730	YG0I_SCHPO	Uncharacterized protein C1604.18c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NSA1	FGF21_HUMAN	Fibroblast growth factor 21	17623664	Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21.

Q9BYN0	SRXN1_HUMAN	Sulfiredoxin-1	15448164	Characterization of mammalian sulfiredoxin and its reactivation of hyperoxidized peroxiredoxin through reduction of cysteine sulfinic acid in the active site to cysteine.

Q99717	SMAD5_HUMAN	Mothers against decapentaplegic homolog 5	9759503	TGF-beta signal transduction.

P85510	CBG29_UNIPI	Calcium-binding shell glycoprotein P29	18810748	Nacre calcification in the freshwater mussel Unio pictorum: carbonic anhydrase activity and purification of a 95 kDa calcium-binding glycoprotein.

P41222	PTGDS_HUMAN	Prostaglandin-H2 D-isomerase	1902577	Human brain prostaglandin D synthase has been evolutionarily differentiated from lipophilic-ligand carrier proteins.

P20809	IL11_HUMAN	Interleukin-11	2145578	Molecular cloning of a cDNA encoding interleukin 11, a stromal cell- derived lymphopoietic and hematopoietic cytokine.

Q12447	PAA1_YEAST	Polyamine N-acetyltransferase 1	11559708	Characterization of the Saccharomyces cerevisiae homolog of the melatonin rhythm enzyme arylalkylamine N-acetyltransferase (EC 2.3.1.87).

Q99884	SC6A7_HUMAN	Sodium-dependent proline transporter	7651355	Human brain-specific L-proline transporter: molecular cloning, functional expression, and chromosomal localization of the gene in human and mouse genomes.

O94328	MU118_SCHPO	Meiotically up-regulated gene 118 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q6AYL6	SPT18_RAT	Spermatogenesis-associated protein 18	15236321	Complementary DNA cloning of rat spetex-1, a spermatid-expressing gene-1, encoding a 63 kDa cytoplasmic protein of elongate spermatids.

Q17381	PHA4_CAEEL	Defective pharyngeal development protein 4	17250823	PHA-4/FoxA cooperates with TAM-1/TRIM to regulate cell fate restriction in the C. elegans foregut.

P34160	NCBP1_YEAST	Nuclear cap-binding protein complex subunit 1	8811086	A yeast cap binding protein complex (yCBC) acts at an early step in pre-mRNA splicing.

P25490	TYY1_HUMAN	Transcriptional repressor protein YY1	9016636	Yeast two-hybrid cloning of a novel zinc finger protein that interacts with the multifunctional transcription factor YY1.

Q84JG2	SWI3B_ARATH	SWI/SNF complex subunit SWI3B	12140326	AtSWI3B, an Arabidopsis homolog of SWI3, a core subunit of yeast Swi/Snf chromatin remodeling complex, interacts with FCA, a regulator of flowering time.

P28358	HXD10_HUMAN	Homeobox protein Hox-D10	1756725	HOX4 genes encode transcription factors with potential auto- and cross-regulatory capacities.

P06883	GLUC_RAT	Glucagon	6548696	Pre-proglucagon messenger ribonucleic acid: nucleotide and encoded amino acid sequences of the rat pancreatic complementary deoxyribonucleic acid.

P23246	SFPQ_HUMAN	Splicing factor, proline- and glutamine-rich	10653975	Differential nuclear localization and nuclear matrix association of the splicing factors PSF and PTB.

P31645	SC6A4_HUMAN	Sodium-dependent serotonin transporter	19270731	The cellular distribution of serotonin transporter is impeded on serotonin-altered vimentin network.

Q9BYG0	B3GN5_HUMAN	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5	11384981	Cloning of a mouse beta 1,3 N-acetylglucosaminyltransferase GlcNAc(beta 1,3)Gal(beta 1,4)Glc-ceramide synthase gene encoding the key regulator of lacto-series glycolipid biosynthesis.

P53041	PPP5_HUMAN	Serine/threonine-protein phosphatase 5	7925273	A novel human protein serine/threonine phosphatase, which possesses four tetratricopeptide repeat motifs and localizes to the nucleus.

Q8VDD9	PHIP_MOUSE	PH-interacting protein	11018022	Cloning and characterization of PHIP, a novel insulin receptor substrate-1 pleckstrin homology domain interacting protein.

P41043	GST1_DROME	Glutathione S-transferase S1	1445191	Isolation of a Drosophila gene encoding glutathione S-transferase.

Q39011	KSG7_ARATH	Shaggy-related protein kinase eta	12114546	The GSK3-like kinase BIN2 phosphorylates and destabilizes BZR1, a positive regulator of the brassinosteroid signaling pathway in Arabidopsis.

P30902	ATP7_YEAST	ATP synthase subunit d, mitochondrial	1832157	ATP synthase of yeast mitochondria. Characterization of subunit d and sequence analysis of the structural gene ATP7.

Q01726	MSHR_HUMAN	Melanocyte-stimulating hormone receptor	7581459	Variants of the melanocyte-stimulating hormone receptor gene are associated with red hair and fair skin in humans.

P25344	STE50_YEAST	Protein STE50	16337230	Saccharomyces cerevisiae Ste50 binds the MAPKKK Ste11 through a head- to-tail SAM domain interaction.

Q62231	SIX1_MOUSE	Homeobox protein SIX1	9826681	Expression of myogenin during embryogenesis is controlled by Six/sine oculis homeoproteins through a conserved MEF3 binding site.

P40923	YHZD_SCHPO	Uncharacterized homeobox protein C21B10.13c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O13982	YEC8_SCHPO	Uncharacterized WD repeat-containing protein C25H1.08c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8BMC1	VATG3_MOUSE	V-type proton ATPase subunit G 3	12527205	Diversity of mouse proton-translocating ATPase: presence of multiple isoforms of the C, d and G subunits.

P17752	TPH1_HUMAN	Tryptophan 5-hydroxylase 1	12379098	Three-dimensional structure of human tryptophan hydroxylase and its implications for the biosynthesis of the neurotransmitters serotonin and melatonin.

P31376	SWC3_YEAST	SWR1-complex protein 3	14645854	ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex.

P08684	CP3A4_HUMAN	Cytochrome P450 3A4	15256616	Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone.

O94513	EIF3E_SCHPO	Eukaryotic translation initiation factor 3 subunit E	11705997	Moe1 and spInt6, the fission yeast homologues of mammalian translation initiation factor 3 subunits p66 (eIF3d) and p48 (eIF3e), respectively, are required for stable association of eIF3 subunits.

Q92398	SPM1_SCHPO	Mitogen-activated protein kinase spm1	8943330	The fission yeast pmk1+ gene encodes a novel mitogen-activated protein kinase homolog which regulates cell integrity and functions coordinately with the protein kinase C pathway.

O75351	VPS4B_HUMAN	Vacuolar protein sorting-associated protein 4B	11563910	Mammalian cells express two VPS4 proteins both of which are involved in intracellular protein trafficking.

Q9Y6X8	ZHX2_HUMAN	Zinc fingers and homeoboxes protein 2	12741956	Zinc-fingers and homeoboxes (ZHX) 2, a novel member of the ZHX family, functions as a transcriptional repressor.

Q924N9	PRS28_MOUSE	Serine protease 28	11425330	A novel murine tryptase involved in blastocyst hatching and outgrowth.

Q08199	SIL1_YEAST	Nucleotide exchange factor SIL1	11101517	LHS1 and SIL1 provide a lumenal function that is essential for protein translocation into the endoplasmic reticulum.

P40970	LCB2_YEAST	Serine palmitoyltransferase 2	10713067	Tsc3p is an 80-amino acid protein associated with serine palmitoyltransferase and required for optimal enzyme activity.

Q9VF87	CYFIP_DROME	Cytoplasmic FMR1-interacting protein	15269173	Sra-1 interacts with Kette and Wasp and is required for neuronal and bristle development in Drosophila.

P31647	S6A11_RAT	Sodium- and chloride-dependent GABA transporter 3	1400419	Molecular heterogeneity of the gamma-aminobutyric acid (GABA) transport system. Cloning of two novel high affinity GABA transporters from rat brain.

Q9UGJ0	AAKG2_HUMAN	5'-AMP-activated protein kinase subunit gamma-2	11371514	Mutations in the gamma(2) subunit of AMP-activated protein kinase cause familial hypertrophic cardiomyopathy: evidence for the central role of energy compromise in disease pathogenesis.

Q5A0L9	SMP3_CANAL	GPI mannosyltransferase 4	15470093	Deficiencies in the essential Smp3 mannosyltransferase block glycosylphosphatidylinositol assembly and lead to defects in growth and cell wall biogenesis in Candida albicans.

Q8CFA7	KLF17_MOUSE	Krueppel-like factor 17	19801974	KLF17 is a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer.

Q9LJR3	SPA3_ARATH	Protein SPA1-RELATED 3	12887588	The SPA1-like proteins SPA3 and SPA4 repress photomorphogenesis in the light.

Q9NSD9	SYFB_HUMAN	Phenylalanyl-tRNA synthetase beta chain	10049785	Human phenylalanyl-tRNA synthetase: cloning, characterization of the deduced amino acid sequences in terms of the structural domains and coordinately regulated expression of the alpha and beta subunits in chronic myeloid leukemia cells.

Q9H0R8	GBRL1_HUMAN	Gamma-aminobutyric acid receptor-associated protein-like 1	16431922	GEC1 interacts with the kappa opioid receptor and enhances expression of the receptor.

Q0WVL7	GOGC5_ARATH	Golgin candidate 5	18182439	Localization and domain characterization of Arabidopsis golgin candidates.

O09106	HDAC1_MOUSE	Histone deacetylase 1	16085498	The PHD finger/bromodomain of NoRC interacts with acetylated histone H4K16 and is sufficient for rDNA silencing.

P29457	SERPH_RAT	Serpin H1	1654327	A collagen-binding protein in the endoplasmic reticulum of myoblasts exhibits relationship with serine protease inhibitors.

P23786	CPT2_HUMAN	Carnitine O-palmitoyltransferase 2, mitochondrial	7711730	Carnitine palmitoyltransferase II deficiency: structure of the gene and characterization of two novel disease-causing mutations.

Q9MBA1	CAO_ARATH	Chlorophyllide a oxygenase, chloroplastic	10758481	Cloning and functional expression of the gene encoding the key enzyme for chlorophyll b biosynthesis (CAO) from Arabidopsis thaliana.

P0A9K9	SLYD_ECOLI	FKBP-type peptidyl-prolyl cis-trans isomerase slyD	17720786	The peptidyl-prolyl isomerase activity of SlyD is not required for maturation of Escherichia coli hydrogenase.

P49789	FHIT_HUMAN	Bis(5'-adenosyl)-triphosphatase	15007172	Fhit is a physiological target of the protein kinase Src.

Q9UT98	YL41_SCHPO	Uncharacterized kinase C323.01c, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O74525	YJ44_SCHPO	Uncharacterized membrane protein C70.04c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9C0U7	VPS5_SCHPO	Vacuolar protein sorting-associated protein vps5	15189449	Sorting nexin homologues are targets of phosphatidylinositol 3- phosphate in sporulation of Schizosaccharomyces pombe.

Q9QXT3	NAT8_RAT	N-acetyltransferase 8	11397015	Overexpression of camello, a member of a novel protein family, reduces blastomere adhesion and inhibits gastrulation in Xenopus laevis.

Q67YU0	CKX5_ARATH	Cytokinin dehydrogenase 5	14555694	Cytokinin-deficient transgenic Arabidopsis plants show multiple developmental alterations indicating opposite functions of cytokinins in the regulation of shoot and root meristem activity.

P38013	AHP1_YEAST	Peroxiredoxin type-2	10681558	Distinct physiological functions of thiol peroxidase isoenzymes in Saccharomyces cerevisiae.

Q9QWS8	KCNH8_RAT	Potassium voltage-gated channel subfamily H member 8	9714851	Cloning of a mammalian elk potassium channel gene and EAG mRNA distribution in rat sympathetic ganglia.

Q6VRB0	ANM1B_XENLA	Protein arginine N-methyltransferase 1-B	16214893	The Ca2+-induced methyltransferase xPRMT1b controls neural fate in amphibian embryo.

Q95ZG4	SPC98_DICDI	Spindle pole body component 98	12018385	Molecular analysis of the cytosolic Dictyostelium gamma-tubulin complex.

Q9NDJ2	DOM_DROME	Helicase domino	15528408	Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions.

O88813	ACSL5_RAT	Long-chain-fatty-acid--CoA ligase 5	9722683	A novel acyl-CoA synthetase, ACS5, expressed in intestinal epithelial cells and proliferating preadipocytes.

Q7T103	P5F11_XENLA	POU domain, class 5, transcription factor 1.1	1732736	Sequential expression of multiple POU proteins during amphibian early development.

Q9UUD0	YNQA_SCHPO	Uncharacterized protein C19C2.10	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q05764	ADDB_RAT	Beta-adducin	2059221	Molecular cloning of an adducin-like protein: evidence of a polymorphism in the normotensive and hypertensive rats of the Milan strain.

A2AMM0	MURC_MOUSE	Muscle-related coiled-coil protein	18332105	MURC, a muscle-restricted coiled-coil protein that modulates the Rho/ROCK pathway, induces cardiac dysfunction and conduction disturbance.

Q9M7T0	PRX2F_ARATH	Peroxiredoxin-2F, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

O94921	CDK14_HUMAN	Cell division protein kinase 14	16775625	A Cdc2-related protein kinase hPFTAIRE1 from human brain interacting with 14-3-3 proteins.

Q04636	POB3_YEAST	FACT complex subunit POB3	10413469	Spt16 and Pob3 of Saccharomyces cerevisiae form an essential, abundant heterodimer that is nuclear, chromatin-associated, and copurifies with DNA polymerase alpha.

Q6P2Q9	PRP8_HUMAN	Pre-mRNA-processing-splicing factor 8	9774689	The human U5-220kD protein (hPrp8) forms a stable RNA-free complex with several U5-specific proteins, including an RNA unwindase, a homologue of ribosomal elongation factor EF-2, and a novel WD-40 protein.

Q55FT4	TSUA_DICDI	Probable serine/threonine-protein kinase tsuA	18708585	tsunami, the Dictyostelium homolog of the Fused kinase, is required for polarization and chemotaxis.

Q9FYG2	CMTA4_ARATH	Calmodulin-binding transcription activator 4	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

P42528	ARP3_DICDI	Actin-related protein 3	17296313	Vectors for expression of proteins with single or combinatorial fluorescent protein and tandem affinity purification tags in Dictyostelium.

Q53083	PSB2_RHOER	Proteasome subunit beta 2	9000518	Subunit topology of the Rhodococcus proteasome.

P06280	AGAL_HUMAN	Alpha-galactosidase A	7911050	Molecular basis of Fabry disease: mutations and polymorphisms in the human alpha-galactosidase A gene.

P13236	CCL4_HUMAN	C-C motif chemokine 4	2462251	Identification, cloning, and characterization of an immune activation gene.

P92186	LIN28_CAEEL	Protein lin-28	12871707	The time of appearance of the C. elegans let-7 microRNA is transcriptionally controlled utilizing a temporal regulatory element in its promoter.

Q9BMN8	LAR_CAEEL	Tyrosine-protein phosphatase Lar-like	11959824	The C. elegans LAR-like receptor tyrosine phosphatase PTP-3 and the VAB-1 Eph receptor tyrosine kinase have partly redundant functions in morphogenesis.

Q08722	CD47_HUMAN	Leukocyte surface antigen CD47	15383453	Adhesion of human T cells to antigen-presenting cells through SIRPbeta2-CD47 interaction costimulates T-cell proliferation.

Q924C1	XPO5_MOUSE	Exportin-5	12426392	Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm.

P54849	EMP1_HUMAN	Epithelial membrane protein 1	8996089	Characterization of a tumor-associated gene, a member of a novel family of genes encoding membrane glycoproteins.

O74968	RU1A_SCHPO	U1 small nuclear ribonucleoprotein usp102	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9M384	SCR_ARATH	Protein SCARECROW	17785527	Arabidopsis JACKDAW and MAGPIE zinc finger proteins delimit asymmetric cell division and stabilize tissue boundaries by restricting SHORT-ROOT action.

P49077	PYRB_ARATH	Aspartate carbamoyltransferase, chloroplastic	8041358	Heterospecific cloning of Arabidopsis thaliana cDNAs by direct complementation of pyrimidine auxotrophic mutants of Saccharomyces cerevisiae. I. Cloning and sequence analysis of two cDNAs catalysing the second, fifth and sixth steps of the de novo pyrimidine biosynthesis pathway.

P11715	CP17A_RAT	Steroid 17-alpha-hydroxylase/17,20 lyase	2786990	Rat P450(17 alpha) from testis: characterization of a full-length cDNA encoding a unique steroid hydroxylase capable of catalyzing both delta 4- and delta 5-steroid-17,20-lyase reactions.

Q11120	OFD1_SCHPO	PKHD-type hydroxylase ofd1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P40056	GET2_YEAST	Golgi to ER traffic protein 2	14562095	Global analysis of protein localization in budding yeast.

O00341	EAA5_HUMAN	Excitatory amino acid transporter 5	9108121	Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance.

Q7TMB3	PPR3C_MOUSE	Protein phosphatase 1 regulatory subunit 3C	10683377	Activation of direct and indirect pathways of glycogen synthesis by hepatic overexpression of protein targeting to glycogen.

O94647	PPK24_SCHPO	Serine/threonine-protein kinase ppk24, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9URY1	PPK16_SCHPO	Serine/threonine-protein kinase ppk16	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9WTX2	PRKRA_MOUSE	Interferon-inducible double stranded RNA-dependent protein kinase activator A	10336432	RAX, a cellular activator for double-stranded RNA-dependent protein kinase during stress signaling.

Q9BZZ2	SN_HUMAN	Sialoadhesin	11133773	Characterization of human sialoadhesin, a sialic acid binding receptor expressed by resident and inflammatory macrophage populations.

O55012	PICA_RAT	Phosphatidylinositol-binding clathrin assembly protein	11161218	Simultaneous binding of PtdIns(4,5)P2 and clathrin by AP180 in the nucleation of clathrin lattices on membranes.

Q9Y231	FUT9_HUMAN	Alpha-(1,3)-fucosyltransferase	10386598	Alpha-1,3-fucosyltransferase IX (Fuc-TIX) is very highly conserved between human and mouse; molecular cloning, characterization and tissue distribution of human Fuc-TIX.

Q96T76	MMS19_HUMAN	MMS19 nucleotide excision repair protein homolog	11279242	The human homologue of the yeast DNA repair and TFIIH regulator MMS19 is an AF-1-specific coactivator of estrogen receptor.

Q5XM24	APRA_DICDI	Autocrine proliferation repressor protein A	16176950	A secreted factor represses cell proliferation in Dictyostelium.

O14268	YFPD_SCHPO	Uncharacterized protein C7D4.13c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8AV13	ANM1A_XENLA	Protein arginine N-methyltransferase 1-A	19047371	Novel functions of protein arginine methyltransferase 1 in thyroid hormone receptor-mediated transcription and in the regulation of metamorphic rate in Xenopus laevis.

Q5SF96	AAAP_ANAMM	Appendage-associated protein	15557651	Identification of a novel Anaplasma marginale appendage-associated protein that localizes with actin filaments during intraerythrocytic infection.

P92996	GL120_ARATH	Germin-like protein subfamily 1 member 20	10987552	Arabidopsis thaliana germin-like proteins: common and specific features point to a variety of functions.

P49848	TAF6_HUMAN	Transcription initiation factor TFIID subunit 6	7667268	Evolutionary conservation of human TATA-binding-polypeptide- associated factors TAFII31 and TAFII80 and interactions of TAFII80 with other TAFs and with general transcription factors.

P36775	LONM_YEAST	Lon protease homolog, mitochondrial	8810243	Promotion of mitochondrial membrane complex assembly by a proteolytically inactive yeast Lon.

Q9R1M5	NALP5_MOUSE	NACHT, LRR and PYD domains-containing protein 5	10754103	Mater encodes a maternal protein in mice with a leucine-rich repeat domain homologous to porcine ribonuclease inhibitor.

O43924	PDE6D_HUMAN	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	11980706	The complex of Arl2-GTP and PDE delta: from structure to function.

Q13797	ITA9_HUMAN	Integrin alpha-9	8245132	Sequence and tissue distribution of the integrin alpha 9 subunit, a novel partner of beta 1 that is widely distributed in epithelia and muscle.

Q8TGH6	GDA1_CANAL	Guanosine-diphosphatase	12455990	The Golgi GDPase of the fungal pathogen Candida albicans affects morphogenesis, glycosylation, and cell wall properties.

O95379	TFIP8_HUMAN	Tumor necrosis factor alpha-induced protein 8	14724590	Expression of SCC-S2, an antiapoptotic molecule, correlates with enhanced proliferation and tumorigenicity of MDA-MB 435 cells.

Q9V6L9	FBSP1_DROME	F-box/SPRY domain-containing protein 1	17697379	DFsn collaborates with Highwire to down-regulate the Wallenda/DLK kinase and restrain synaptic terminal growth.

Q9Y5S8	NOX1_HUMAN	NADPH oxidase 1	10485709	Cell transformation by the superoxide-generating oxidase Mox1.

Q13418	ILK_HUMAN	Integrin-linked protein kinase	10871859	Cloning of an isoform of integrin-linked kinase (ILK) that is upregulated in HT-144 melanoma cells following TGF-beta1 stimulation.

P62330	ARF6_HUMAN	ADP-ribosylation factor 6	15509780	The TBC (Tre-2/Bub2/Cdc16) domain protein TRE17 regulates plasma membrane-endosomal trafficking through activation of Arf6.

Q96RN5	MED15_HUMAN	Mediator of RNA polymerase II transcription subunit 15	16799563	An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis.

O81439	PAP1_ARATH	Probable plastid-lipid-associated protein 1, chloroplastic	16414959	Tocopherol cyclase (VTE1) localization and vitamin E accumulation in chloroplast plastoglobule lipoprotein particles.

Q8LG88	TDT_ARATH	Tonoplast dicarboxylate transporter	15728336	Impaired pH homeostasis in Arabidopsis lacking the vacuolar dicarboxylate transporter and analysis of carboxylic acid transport across the tonoplast.

Q8IWU2	LMTK2_HUMAN	Serine/threonine-protein kinase LMTK2	12393858	A novel transmembrane Ser/Thr kinase complexes with protein phosphatase-1 and inhibitor-2.

P19881	PNPP_YEAST	4-nitrophenylphosphatase	2558283	Molecular characterization of a specific p-nitrophenylphosphatase gene, PHO13, and its mapping by chromosome fragmentation in Saccharomyces cerevisiae.

Q9STX3	GID2_ARATH	F-box protein GID2	15155881	The Arabidopsis F-box protein SLEEPY1 targets gibberellin signaling repressors for gibberellin-induced degradation.

P53297	PBP1_YEAST	PAB1-binding protein 1	14562095	Global analysis of protein localization in budding yeast.

O60168	YHC4_SCHPO	Uncharacterized endonuclease C19F8.04c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9C6B8	PINI_ARATH	Auxin efflux carrier component 1	9856939	Regulation of polar auxin transport by AtPIN1 in Arabidopsis vascular tissue.

Q9Y5Z0	BACE2_HUMAN	Beta-secretase 2	11423558	BACE2 functions as an alternative alpha-secretase in cells.

Q8RWZ1	SUB_ARATH	Protein STRUBBELIG	15951420	STRUBBELIG defines a receptor kinase-mediated signaling pathway regulating organ development in Arabidopsis.

Q9M3G7	ATM_ARATH	Serine/threonine-protein kinase ATM	16166376	ATM and ATR make distinct contributions to chromosome end protection and the maintenance of telomeric DNA in Arabidopsis.

P38273	CCZ1_YEAST	Vacuolar fusion protein CCZ1	11590240	The Ccz1 protein interacts with Ypt7 GTPase during fusion of multiple transport intermediates with the vacuole in S. cerevisiae.

P93033	FUM1_ARATH	Fumarate hydratase 1, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q03497	STE20_YEAST	Serine/threonine-protein kinase STE20	1464311	The protein kinase homologue Ste20p is required to link the yeast pheromone response G-protein beta gamma subunits to downstream signalling components.

O14744	ANM5_HUMAN	Protein arginine N-methyltransferase 5	16087681	Toward an assembly line for U7 snRNPs: interactions of U7-specific Lsm proteins with PRMT5 and SMN complexes.

Q9LU91	SKI14_ARATH	F-box protein SKIP14	12795696	Protein interaction analysis of SCF ubiquitin E3 ligase subunits from Arabidopsis.

Q9UKM7	MA1B1_HUMAN	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase	10409699	Identification, expression, and characterization of a cDNA encoding human endoplasmic reticulum mannosidase I, the enzyme that catalyzes the first mannose trimming step in mammalian Asn-linked oligosaccharide biosynthesis.

Q62975	ZPI_RAT	Protein Z-dependent protease inhibitor	8670294	cDNA cloning of rasp-1, a novel gene encoding a plasma protein associated with liver regeneration.

Q8RUW5	SCP8_ARATH	Serine carboxypeptidase-like 8	10948250	Cloning of the SNG1 gene of Arabidopsis reveals a role for a serine carboxypeptidase-like protein as an acyltransferase in secondary metabolism.

Q3V3I2	GNAT3_MOUSE	Guanine nucleotide-binding protein G(t) subunit alpha-3	10570481	Ggamma13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium.

Q9S777	4CL3_ARATH	4-coumarate--CoA ligase 3	10417722	Three 4-coumarate:coenzyme A ligases in Arabidopsis thaliana represent two evolutionarily divergent classes in angiosperms.

Q9UU80	CWF18_SCHPO	Cell cycle control protein cwf18	11884590	Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

Q54S83	MIDA_DICDI	Protein midA, mitochondrial	16507593	Functional genomics in Dictyostelium: midA, a new conserved protein, is required for mitochondrial function and development.

P42893	ECE1_RAT	Endothelin-converting enzyme 1	8034569	Cloning and functional expression of endothelin-converting enzyme from rat endothelial cells.

Q9BWW9	APOL5_HUMAN	Apolipoprotein L5	11374903	The human apolipoprotein L gene cluster: identification, classification, and sites of distribution.

Q9M9Y8	CRTSO_ARATH	Carotenoid isomerase, chloroplastic	11884677	Identification of the carotenoid isomerase provides insight into carotenoid biosynthesis, prolamellar body formation, and photomorphogenesis.

P24462	CP3A7_HUMAN	Cytochrome P450 3A7	2722762	Molecular cloning and sequence analysis of cDNA containing the entire coding region for human fetal liver cytochrome P-450.

P54313	GBB2_RAT	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2	10970423	Differential modulation of N-type 1B and P/Q-type 1A calcium channels by different G protein subunit isoforms.

Q38937	RAC5_ARATH	Rac-like GTP-binding protein ARAC5	10798620	Localization of AtROP4 and AtROP6 and interaction with the guanine nucleotide dissociation inhibitor AtRhoGDI1 from Arabidopsis.

P06331	HV209_HUMAN	Ig heavy chain V-II region ARH-77	3922855	A cloned human immunoglobulin heavy chain gene with a novel direct- repeat sequence in 5' flanking region.

Q00177	XYNC_EMENI	Endo-1,4-beta-xylanase C	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

Q8K4Q6	NEIL1_MOUSE	Endonuclease 8-like 1	12200441	A back-up glycosylase in Nth1 knock-out mice is a functional Nei (endonuclease VIII) homologue.

P11035	NIA2_ARATH	Nitrate reductase [NADH] 2	8510658	Identification and characterization of a chlorate-resistant mutant of Arabidopsis thaliana with mutations in both nitrate reductase structural genes NIA1 and NIA2.

Q9UUG5	MLR1_SCHPO	Myosin regulatory light chain 1	11069761	The S. pombe rlc1 gene encodes a putative myosin regulatory light chain that binds the type II myosins myo3p and myo2p.

Q10135	LSD2_SCHPO	Lysine-specific histone demethylase 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O43294	TGFI1_HUMAN	Transforming growth factor beta-1-induced transcript 1 protein	12177201	The multiple LIM domain-containing adaptor protein Hic-5 synaptically colocalizes and interacts with the dopamine transporter.

Q8WZK3	IBP1_SCHPO	Dual specificity phosphatase ibp1	14508607	Ibp1p, a novel Cdc25-related phosphatase, suppresses Schizosaccharomyces pombe hsk1 (cdc7).

Q07478	SUB2_YEAST	ATP-dependent RNA helicase SUB2	11979277	TREX is a conserved complex coupling transcription with messenger RNA export.

P14174	MIF_HUMAN	Macrophage migration inhibitory factor	17526494	Alternative chemical modifications reverse the binding orientation of a pharmacophore scaffold in the active site of macrophage migration inhibitory factor.

Q2XPP4	ATG4B_ORYSI	Cysteine protease ATG4B	17082902	Identification and characterization of two rice autophagy associated genes, OsAtg8 and OsAtg4.

P45568	DXR_ECOLI	1-deoxy-D-xylulose 5-phosphate reductoisomerase	10787409	Characterization of 1-deoxy-D-xylulose 5-phosphate reductoisomerase, an enzyme involved in isopentenyl diphosphate biosynthesis, and identification of its catalytic amino acid residues.

P02406	RL28_YEAST	60S ribosomal protein L28	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q8IZL8	PELP1_HUMAN	Proline-, glutamic acid- and leucine-rich protein 1	15960975	Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

Q01989	MYS9_DROME	Myosin heavy chain 95F	9472041	A class VI unconventional myosin is associated with a homologue of a microtubule-binding protein, cytoplasmic linker protein-170, in neurons and at the posterior pole of Drosophila embryos.

Q6P9Z1	SMRD3_MOUSE	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3	17640523	An essential switch in subunit composition of a chromatin remodeling complex during neural development.

Q07912	ACK1_HUMAN	Activated CDC42 kinase 1	10587647	Melanoma chondroitin sulphate proteoglycan regulates cell spreading through Cdc42, Ack-1 and p130cas.

P40992	RRN7_YEAST	RNA polymerase I-specific transcription initiation factor RRN7	8887672	A novel 66-kilodalton protein complexes with Rrn6, Rrn7, and TATA- binding protein to promote polymerase I transcription initiation in Saccharomyces cerevisiae.

P48011	RPAB4_SCHPO	DNA-directed RNA polymerases I, II, and III subunit RPABC4	9290054	Molecular cloning and characterization of cDNA of the rpc10+ gene encoding the smallest subunit of nuclear RNA polymerases of Schizosaccharomyces pombe.

Q8VZK9	CSLE1_ARATH	Cellulose synthase-like protein E1	16618929	Mapping the Arabidopsis organelle proteome.

Q16537	2A5E_HUMAN	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform	8703017	The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm.

P04904	GSTA3_RAT	Glutathione S-transferase alpha-3	10215608	Genomic cloning and characterization of the rat glutathione S- transferase-A3-subunit gene.

Q9EQD0	FZD5_MOUSE	Frizzled-5	11092808	Mouse Wnt receptor gene Fzd5 is essential for yolk sac and placental angiogenesis.

Q08490	SGO1_YEAST	Shugoshin	15062096	Maintenance of cohesin at centromeres after meiosis I in budding yeast requires a kinetochore-associated protein related to MEI-S332.

O60880	SH21A_HUMAN	SH2 domain-containing protein 1A	9774102	The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM.

P0ACR0	ALLS_ECOLI	HTH-type transcriptional activator AllS	12460564	Regulation of the Escherichia coli allantoin regulon: coordinated function of the repressor AllR and the activator AllS.

P53350	PLK1_HUMAN	Serine/threonine-protein kinase PLK1	18615013	Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery.

Q8NEM7	FA48A_HUMAN	Protein FAM48A	16751104	p38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation.

P70169	DOC2B_MOUSE	Double C2-like domain-containing protein beta	19033398	DOC2B: a novel syntaxin-4 binding protein mediating insulin-regulated GLUT4 vesicle fusion in adipocytes.

P29375	KDM5A_HUMAN	Lysine-specific demethylase 5A	8414517	Characterization of the retinoblastoma binding proteins RBP1 and RBP2.

Q9NRJ7	PCDBG_HUMAN	Protocadherin beta-16	11322959	The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number.

Q8VXX5	SKS1_ARATH	Monocopper oxidase-like protein SKS1	12805588	Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis.

P35402	ERD2_ARATH	ER lumen protein retaining receptor	8248265	The Arabidopsis endoplasmic reticulum retention receptor functions in yeast.

O75636	FCN3_HUMAN	Ficolin-3	11907111	Activation of the lectin complement pathway by H-ficolin (Hakata antigen).

P32722	PORD_PSEAE	Porin D	8843159	Protein D2 porin of the Pseudomonas aeruginosa outer membrane bears the protease activity.

P37263	YC16_YEAST	UPF0743 protein YCR087C-A	14562095	Global analysis of protein localization in budding yeast.

Q8VYE2	TIM50_ARATH	Mitochondrial import inner membrane translocase subunit TIM50	14730085	A transcriptomic and proteomic characterization of the Arabidopsis mitochondrial protein import apparatus and its response to mitochondrial dysfunction.

Q16543	CDC37_HUMAN	Hsp90 co-chaperone Cdc37	11036079	Hsp90 regulates p50(cdc37) function during the biogenesis of the active conformation of the heme-regulated eIF2 alpha kinase.

Q8JZS0	LIN7A_MOUSE	Protein lin-7 homolog A	14622577	Role of beta-catenin in synaptic vesicle localization and presynaptic assembly.

P11142	HSP7C_HUMAN	Heat shock cognate 71 kDa protein	9305631	BAG-1 modulates the chaperone activity of Hsp70/Hsc70.

Q9VZU2	HHAT_DROME	Protein-cysteine N-palmitoyltransferase Rasp	11509241	Sightless has homology to transmembrane acyltransferases and is required to generate active Hedgehog protein.

Q8NEB9	PK3C3_HUMAN	Phosphatidylinositol 3-kinase catalytic subunit type 3	19270696	Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages.

Q41560	HS16B_WHEAT	16.9 kDa class I heat shock protein 2	11702068	Crystal structure and assembly of a eukaryotic small heat shock protein.

P15108	HSC82_YEAST	ATP-dependent molecular chaperone HSC82	2674684	hsp82 is an essential protein that is required in higher concentrations for growth of cells at higher temperatures.

Q04396	LPP1_YEAST	Lipid phosphate phosphatase 1	10685032	Enzymological properties of the LPP1-encoded lipid phosphatase from Saccharomyces cerevisiae.

O70300	PSPN_MOUSE	Persephin	9491986	Persephin, a novel neurotrophic factor related to GDNF and neurturin.

Q79V62	KAIA_THEEB	Circadian clock protein kaiA	15256595	Structure of the C-terminal domain of the clock protein KaiA in complex with a KaiC-derived peptide: implications for KaiC regulation.

Q9Y264	ANGP4_HUMAN	Angiopoietin-4	10051567	Angiopoietins 3 and 4: diverging gene counterparts in mice and humans.

Q9LTR2	TGD2_ARATH	Protein TRIGALACTOSYLDIACYLGLYCEROL 2, chloroplastic	12766230	Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.

Q12948	FOXC1_HUMAN	Forkhead box protein C1	12614756	A family with Axenfeld-Rieger syndrome and Peters Anomaly caused by a point mutation (Phe112Ser) in the FOXC1 gene.

P75823	LTAE_ECOLI	Low specificity L-threonine aldolase	9692922	Gene cloning, biochemical characterization and physiological role of a thermostable low-specificity L-threonine aldolase from Escherichia coli.

A0T2N3	APJB_DANRE	Apelin receptor B	17336906	The G protein-coupled receptor Agtrl1b regulates early development of myocardial progenitors.

Q6S000	KIF12_DICDI	Kinesin-related protein 12	15546981	A mitotic kinesin-like protein required for normal karyokinesis, myosin localization to the furrow, and cytokinesis in Dictyostelium.

Q54KD9	RANG_DICDI	Ran-specific GTPase-activating protein homolog	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P22696	ESS1_YEAST	Peptidyl-prolyl cis-trans isomerase ESS1	10531363	Phospho-carboxyl-terminal domain binding and the role of a prolyl isomerase in pre-mRNA 3'-End formation.

Q06815	MRL1_YEAST	Mannose 6-phosphate receptor-like protein 1	11470415	A yeast homolog of the mammalian mannose 6-phosphate receptors contributes to the sorting of vacuolar hydrolases.

Q13043	STK4_HUMAN	Serine/threonine-protein kinase 4	8816758	Newly identified stress-responsive protein kinases, Krs-1 and Krs- 2.

Q10984	FUT2_RAT	Galactoside 2-alpha-L-fucosyltransferase 2	11179967	Comparison of the three rat GDP-L-fucose:beta-D-galactoside 2-alpha- L-fucosyltransferases FTA, FTB and FTC.

Q9N2P6	VEPD_DROME	Ventrally expressed gene D protein	8816799	Identification of novel genes in Drosophila reveals the complex regulation of early gene activity in the mesoderm.

Q96I99	SUCB2_HUMAN	Succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial	9765291	Genetic evidence for the expression of ATP- and GTP-specific succinyl-CoA synthetases in multicellular eucaryotes.

O45551	IF4E1_CAEEL	Eukaryotic translation initiation factor 4E-1	11641215	An isoform of eIF4E is a component of germ granules and is required for spermatogenesis in C. elegans.

Q01726	MSHR_HUMAN	Melanocyte-stimulating hormone receptor	19737927	Mahogunin ring finger-1 (MGRN1) E3 ubiquitin ligase inhibits signaling from melanocortin receptor by competition with Galphas.

Q05022	RRP5_YEAST	rRNA biogenesis protein RRP5	8896463	RRP5 is required for formation of both 18S and 5.8S rRNA in yeast.

P19658	EXO70_YEAST	Exocyst complex component EXO70	8978675	The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae.

Q9S7I0	TADA_ARATH	tRNA-specific adenosine deaminase, chloroplastic	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P0CAZ0	TTL3B_TETTH	Tubulin glycylase 3B	19531357	TTLL3 Is a tubulin glycine ligase that regulates the assembly of cilia.

Q86W42	THOC6_HUMAN	THO complex subunit 6 homolog	15833825	Linking transcriptional elongation and messenger RNA export to metastatic breast cancers.

Q13972	RGRF1_HUMAN	Ras-specific guanine nucleotide-releasing factor 1	1379731	Identification of a mammalian gene structurally and functionally related to the CDC25 gene of Saccharomyces cerevisiae.

P57789	KCNKA_HUMAN	Potassium channel subfamily K member 10	10880510	Human TREK2, a 2P domain mechano-sensitive K+ channel with multiple regulations by polyunsaturated fatty acids, lysophospholipids and Gs, Gi, and Gq protein-coupled receptors.

Q9R803	SSED_SALTY	Secreted effector protein sseD	15256549	The SPI2-encoded SseA chaperone has discrete domains required for SseB stabilization and export, and binds within the C-terminus of SseB and SseD.

Q9P2N4	ATS9_HUMAN	A disintegrin and metalloproteinase with thrombospondin motifs 9	10936055	ADAMTS 9, a novel member of the ADAM-TS/Metallospondin gene family.

O14920	IKKB_HUMAN	Inhibitor of nuclear factor kappa-B kinase subunit beta	9346484	IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF- kappaB activation.

Q55356	PSB28_SYNY3	Photosystem II reaction center Psb28 protein	12069591	Proteomic analysis of a highly active photosystem II preparation from the cyanobacterium Synechocystis sp. PCC 6803 reveals the presence of novel polypeptides.

O74846	SEC6_SCHPO	Exocyst complex component sec6	11854409	The multiprotein exocyst complex is essential for cell separation in Schizosaccharomyces pombe.

P20231	TRYB2_HUMAN	Tryptase beta-2	2203827	Cloning and characterization of a second complementary DNA for human tryptase.

Q95V55	FOXO_DROME	Forkhead box protein O	12908874	The Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling.

P38483	ABEC1_RAT	C->U-editing enzyme APOBEC-1	8511591	Molecular cloning of an apolipoprotein B messenger RNA editing protein.

P53961	GPI15_YEAST	Phosphatidylinositol N-acetylglucosaminyltransferase subunit GPI15	11746600	Ynl038wp (Gpi15p) is the Saccharomyces cerevisiae homologue of human Pig-Hp and participates in the first step in glycosylphosphatidylinositol assembly.

Q14315	FLNC_HUMAN	Filamin-C	16076904	The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins.

P22579	SIN3_YEAST	Transcriptional regulatory protein SIN3	14711989	Saccharomyces cerevisiae Sin3p facilitates DNA double-strand break repair.

Q9HGL9	WHI5_SCHPO	Cell cycle transcriptional repressor whi5	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q60591	NFAC2_MOUSE	Nuclear factor of activated T-cells, cytoplasmic 2	11278367	Identification and characterization of a novel nuclear factor of activated T-cells-1 isoform expressed in mouse brain.

P07895	SODM_RAT	Superoxide dismutase [Mn], mitochondrial	2001291	Molecular structure of a functional rat gene for manganese-containing superoxide dismutase.

P38989	SMC2_YEAST	Structural maintenance of chromosomes protein 2	10811823	The condensin complex governs chromosome condensation and mitotic transmission of rDNA.

P36010	NDK_YEAST	Nucleoside diphosphate kinase	18983998	YNK1, the yeast homolog of human metastasis suppressor NM23, is required for repair of UV radiation- and etoposide-induced DNA damage.

Q13216	ERCC8_HUMAN	DNA excision repair protein ERCC-8	7664335	The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH.

O00762	UBE2C_HUMAN	Ubiquitin-conjugating enzyme E2 C	18485873	Mechanism of ubiquitin-chain formation by the human anaphase- promoting complex.

O75558	STX11_HUMAN	Syntaxin-11	9553086	Seven novel mammalian SNARE proteins localize to distinct membrane compartments.

Q9HE18	FAEB_PENFN	Feruloyl esterase B	11082184	A modular esterase from Penicillium funiculosum which releases ferulic acid from plant cell walls and binds crystalline cellulose contains a carbohydrate binding module.

Q9P7D7	LCF2_SCHPO	Long-chain-fatty-acid--CoA ligase 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9LJL4	IPT8_ARATH	Adenylate isopentenyltransferase 8, chloroplastic	11313355	Identification of genes encoding adenylate isopentenyltransferase, a cytokinin biosynthesis enzyme, in Arabidopsis thaliana.

Q12400	TRM10_YEAST	tRNA (guanine-N(1)-)-methyltransferase TRM10	12702816	Identification of the yeast gene encoding the tRNA m1G methyltransferase responsible for modification at position 9.

Q14194	DPYL1_HUMAN	Dihydropyrimidinase-related protein 1	8973361	A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution.

P51532	SMCA4_HUMAN	Transcription activator BRG1	17582821	Structural ramification for acetyl-lysine recognition by the bromodomain of human BRG1 protein, a central ATPase of the SWI/SNF remodeling complex.

Q9DED4	CIRBB_XENLA	Cold-inducible RNA-binding protein B	11095679	CIRP2, a major cytoplasmic RNA-binding protein in Xenopus oocytes.

Q04279	YMX6_YEAST	Uncharacterized protein YMR086W	11914276	Subcellular localization of the yeast proteome.

P61088	UBE2N_HUMAN	Ubiquitin-conjugating enzyme E2 N	11473255	Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13.

O43516	WIPF1_HUMAN	WAS/WASL-interacting protein family member 1	10202051	Mutations that cause the Wiskott-Aldrich syndrome impair the interaction of Wiskott-Aldrich syndrome protein (WASP) with WASP interacting protein.

Q99PE6	NID67_RAT	Putative small membrane protein NID67	11288140	NID67, a small putative membrane protein, is preferentially induced by NGF in PC12 pheochromocytoma cells.

P79958	WT1B_XENLA	Wilms tumor protein homolog B	16818449	The Notch-effector HRT1 gene plays a role in glomerular development and patterning of the Xenopus pronephros anlagen.

Q9M9M4	CSLD3_ARATH	Cellulose synthase-like protein D3	16618929	Mapping the Arabidopsis organelle proteome.

P38907	CHL4_YEAST	Central kinetochore subunit CHL4	8243998	Identification and cloning of the CHL4 gene controlling chromosome segregation in yeast.

Q9HD26	GOPC_HUMAN	Golgi-associated PDZ and coiled-coil motif-containing protein	11707463	A Golgi-associated PDZ domain protein modulates cystic fibrosis transmembrane regulator plasma membrane expression.

P43243	MATR3_HUMAN	Matrin-3	2033075	Molecular cloning of matrin 3. A 125-kilodalton protein of the nuclear matrix contains an extensive acidic domain.

Q9MAH1	TTL1_ARATH	TPR repeat-containing thioredoxin TTL1	16998088	The Arabidopsis tetratricopeptide repeat-containing protein TTL1 is required for osmotic stress responses and abscisic acid sensitivity.

O88600	HSP74_RAT	Heat shock 70 kDa protein 4	10098860	Molecular cloning of a novel member of the HSP110 family of genes, ischemia-responsive protein 94 kDa (irp94), expressed in rat brain after transient forebrain ischemia.

Q9LUW0	LOX5_ARATH	Lipoxygenase 5, chloroplastic	15028209	The Arabidopsis thaliana chloroplast proteome reveals pathway abundance and novel protein functions.

Q9P7S7	NOP58_SCHPO	Nucleolar protein 58	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

A2VD23	STM_DANRE	Protein starmaker	14551434	Control of crystal size and lattice formation by starmaker in otolith biomineralization.

Q8IZP0	ABI1_HUMAN	Abl interactor 1	9593709	Identification of a candidate human spectrin Src homology 3 domain- binding protein suggests a general mechanism of association of tyrosine kinases with the spectrin-based membrane skeleton.

P53322	TNA1_YEAST	High-affinity nicotinic acid transporter	10869563	Transcriptional regulation of the Saccharomyces cerevisiae DAL5 gene family and identification of the high affinity nicotinic acid permease TNA1 (YGR260w).

Q04924	GLU2B_YEAST	Glucosidase 2 subunit beta	14562095	Global analysis of protein localization in budding yeast.

Q9R0M5	TPK1_MOUSE	Thiamin pyrophosphokinase 1	10567383	Molecular cloning and expression of a mouse thiamin pyrophosphokinase cDNA.

Q92570	NR4A3_HUMAN	Nuclear receptor subfamily 4 group A member 3	9573341	Alternative splicing generates isoforms of human neuron-derived orphan receptor-1 (NOR-1) mRNA.

Q9M591	CRD1_ARATH	Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase, chloroplastic	14673103	Arabidopsis CHL27, located in both envelope and thylakoid membranes, is required for the synthesis of protochlorophyllide.

Q9NNZ3	DNJC4_HUMAN	DnaJ homolog subfamily C member 4	9473517	Characterisation of a new human and murine member of the DnaJ family of proteins.

P11880	MURF_ECOLI	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase	2186811	Purification and characterization of the D-alanyl-D-alanine-adding enzyme from Escherichia coli.

Q9UKP5	ATS6_HUMAN	A disintegrin and metalloproteinase with thrombospondin motifs 6	10464288	ADAM-TS5, ADAM-TS6, and ADAM-TS7, novel members of a new family of zinc metalloproteases.

O35973	PER1_MOUSE	Period circadian protein homolog 1	9856465	Mammalian circadian autoregulatory loop: a timeless ortholog and mPer1 interact and negatively regulate CLOCK-BMAL1-induced transcription.

Q02589	ADPRH_RAT	[Protein ADP-ribosylarginine] hydrolase	1375222	Molecular and immunological characterization of ADP-ribosylarginine hydrolases.

P20073	ANXA7_HUMAN	Annexin A7	18256029	Identification of Alix-type and non-Alix-type ALG-2-binding sites in human phospholipid scramblase 3: differential binding to an alternatively spliced isoform and amino acid-substituted mutants.

O96033	MOC2A_HUMAN	Molybdopterin synthase sulfur carrier subunit	12732628	Mechanistic studies of human molybdopterin synthase reaction and characterization of mutants identified in group B patients of molybdenum cofactor deficiency.

P54360	FOJO_DROME	Protein four-jointed	7555705	four-jointed is required for intermediate growth in the proximal- distal axis in Drosophila.

P47074	MAD3_YEAST	Spindle assembly checkpoint component MAD3	11726501	Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores.

P07245	C1TC_YEAST	C-1-tetrahydrofolate synthase, cytoplasmic	14562095	Global analysis of protein localization in budding yeast.

Q02574	MEC3_YEAST	DNA damage checkpoint control protein MEC3	12604797	Yeast Rad17/Mec3/Ddc1: a sliding clamp for the DNA damage checkpoint.

P38326	SWC5_YEAST	SWR1-complex protein 5	14562095	Global analysis of protein localization in budding yeast.

Q9U1H9	NXF1_DROME	Nuclear RNA export factor 1	11780634	Small bristles, the Drosophila ortholog of NXF-1, is essential for mRNA export throughout development.

P53861	ELOA1_YEAST	Elongin-A	10753924	Elongin from Saccharomyces cerevisiae.

Q9S775	PKL_ARATH	CHD3-type chromatin-remodeling factor PICKLE	10570159	PICKLE is a CHD3 chromatin-remodeling factor that regulates the transition from embryonic to vegetative development in Arabidopsis.

P25039	EFGM_YEAST	Elongation factor G, mitochondrial	1935960	Mitochondrial translational-initiation and elongation factors in Saccharomyces cerevisiae.

P20337	RAB3B_HUMAN	Ras-related protein Rab-3B	2501306	The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion.

Q00723	PRP38_YEAST	Pre-mRNA-splicing factor 38	10377396	Purification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins.

Q9UI36	DACH1_HUMAN	Dachshund homolog 1	14525983	DACH1 inhibits transforming growth factor-beta signaling through binding Smad4.

Q96AZ6	ISG20_HUMAN	Interferon-stimulated gene 20 kDa protein	9235947	Molecular cloning of a new interferon-inductible PML nuclear bodies- associated protein.

Q8GUM3	AAP5_ARATH	Amino acid permease 5	18681934	Root uptake of cationic amino acids by Arabidopsis depends on functional expression of amino acid permease 5.

O13807	DDB1_SCHPO	DNA damage-binding protein 1	12857752	Schizosaccharomyces pombe Ddb1 is functionally linked to the replication checkpoint pathway.

Q24338	ESC_DROME	Polycomb protein esc	12697833	A 1-megadalton ESC/E(Z) complex from Drosophila that contains polycomblike and RPD3.

Q0D840	TRXH1_ORYSJ	Thioredoxin H1	19665023	A cold-induced thioredoxin h of rice, OsTrx23, negatively regulates kinase activities of OsMPK3 and OsMPK6 in vitro.

P37059	DHB2_HUMAN	Estradiol 17-beta-dehydrogenase 2	8099587	Expression cloning and characterization of human 17 beta- hydroxysteroid dehydrogenase type 2, a microsomal enzyme possessing 20 alpha-hydroxysteroid dehydrogenase activity.

P21525	FOSLA_DROME	Transcription factor kayak, isoforms A/B/F	2116361	The Drosophila Fos-related AP-1 protein is a developmentally regulated transcription factor.

P21268	FAR1_YEAST	Cyclin-dependent kinase inhibitor FAR1	8066461	Direct inhibition of the yeast cyclin-dependent kinase Cdc28-Cln by Far1.

P13761	2B17_HUMAN	HLA class II histocompatibility antigen, DRB1-7 beta chain	11144299	Molecular, serological and genetic studies on two new HLA-DRB1 alleles -- HLA-DRB1*0704 and HLA-DRB1*1507.

P18613	RAPA_DICDI	Ras-related protein rapA	12186953	Evidence for a role for the Dictyostelium Rap1 in cell viability and the response to osmotic stress.

Q7KTX8	MED13_DROME	Mediator of RNA polymerase II transcription subunit 13	12835386	Two subunits of the Drosophila mediator complex act together to control cell affinity.

P31554	LPTD_ECOLI	LPS-assembly protein lptD	16861298	Identification of a protein complex that assembles lipopolysaccharide in the outer membrane of Escherichia coli.

P0A9M0	LON_ECOLI	Lon protease	8995294	Bacterial protease Lon is a site-specific DNA-binding protein.

Q17667	LNP1_CAEEL	Protein lunapark-1	18279315	The evolutionarily conserved gene LNP-1 is required for synaptic vesicle trafficking and synaptic transmission.

Q02505	MUC3A_HUMAN	Mucin-3A	10512748	Genomic organization and structure of the 3' region of human MUC3: alternative splicing predicts membrane-bound and soluble forms of the mucin.

O44662	NLP31_CAEEL	Neuropeptide-like protein 31	15048112	TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM.

P09895	RL5_RAT	60S ribosomal protein L5	3624282	The primary structure of rat ribosomal protein L5. A comparison of the sequence of amino acids in the proteins that interact with 5 S rRNA.

P38359	SUL1_YEAST	Sulfate permease 1	7616962	Isolation of a cDNA from Saccharomyces cerevisiae that encodes a high affinity sulphate transporter at the plasma membrane.

P35187	SGS1_YEAST	ATP-dependent helicase SGS1	15889139	RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex.

Q8WTS6	SETD7_HUMAN	Histone-lysine N-methyltransferase SETD7	12514135	Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet.

Q94KI8	TPC1_ARATH	Two pore calcium channel protein 1	15539469	The vegetative vacuole proteome of Arabidopsis thaliana reveals predicted and unexpected proteins.

P32793	YSC84_YEAST	Protein YSC84	10512884	The Saccharomyces cerevisiae homologue of human Wiskott-Aldrich syndrome protein Las17p interacts with the Arp2/3 complex.

P32353	ERG3_YEAST	C-5 sterol desaturase	1864507	Cloning, disruption and sequence of the gene encoding yeast C-5 sterol desaturase.

Q9QXV8	SPY2_MOUSE	Protein sprouty homolog 2	10074434	Conserved function of mSpry-2, a murine homolog of Drosophila sprouty, which negatively modulates respiratory organogenesis.

Q91Z79	LIPA3_RAT	Liprin-alpha-3	11797009	RIM1alpha forms a protein scaffold for regulating neurotransmitter release at the active zone.

P43619	NADC_YEAST	Nicotinate-nucleotide pyrophosphorylase [carboxylating]	12062417	Aerobic and anaerobic NAD+ metabolism in Saccharomyces cerevisiae.

Q9V727	ASX_DROME	Polycomb protein Asx	20436459	Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB.

P0AEJ2	ENTC_ECOLI	Isochorismate synthase entC	2139795	Overexpression, purification, and characterization of isochorismate synthase (EntC), the first enzyme involved in the biosynthesis of enterobactin from chorismate.

Q01649	CIK1_YEAST	Spindle pole body-associated protein CIK1	11729143	The Kar3-interacting protein Cik1p plays a critical role in passage through meiosis I in Saccharomyces cerevisiae.

O96553	C1TC_DROME	C-1-tetrahydrofolate synthase, cytoplasmic	9832531	Dominant defects in Drosophila eye pigmentation resulting from a euchromatin-heterochromatin fusion gene.

P58195	PLS1_RAT	Phospholipid scramblase 1	11259432	IgE receptor type I-dependent tyrosine phosphorylation of phospholipid scramblase.

Q9USV2	YHH5_SCHPO	Uncharacterized oxidoreductase C28F2.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P53330	RT102_YEAST	Regulator of Ty1 transposition protein 102	15506919	Proteomic analysis of chromatin-modifying complexes in Saccharomyces cerevisiae identifies novel subunits.

P11441	UBL4A_HUMAN	Ubiquitin-like protein 4A	2829204	A 'housekeeping' gene on the X chromosome encodes a protein similar to ubiquitin.

P32383	PLC1_YEAST	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase 1	12073033	Phospholipase C interacts with Sgd1p and is required for expression of GPD1 and osmoresistance in Saccharomyces cerevisiae.

Q10198	NDC80_SCHPO	Kinetochore protein ndc80	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P53036	SAP4_YEAST	SIT4-associating protein SAP4	8649382	The SAPs, a new family of proteins, associate and function positively with the SIT4 phosphatase.

Q9NS00	C1GLT_HUMAN	Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1	17228361	Variants of C1GALT1 gene are associated with the genetic susceptibility to IgA nephropathy.

Q63248	FOXI2_RAT	Forkhead box protein I2	7683413	Identification of nine tissue-specific transcription factors of the hepatocyte nuclear factor 3/forkhead DNA-binding-domain family.

Q99220	OS9_YEAST	Protein OS-9 homolog	16168372	Yos9 protein is essential for degradation of misfolded glycoproteins and may function as lectin in ERAD.

Q9LRB7	EL5_ORYSJ	E3 ubiquitin-protein ligase EL5	12028574	EL5, a rice N-acetylchitooligosaccharide elicitor-responsive RING-H2 finger protein, is a ubiquitin ligase which functions in vitro in co- operation with an elicitor-responsive ubiquitin-conjugating enzyme, OsUBC5b.

P06727	APOA4_HUMAN	Apolipoprotein A-IV	3080432	The nucleotide and derived amino acid sequence of human apolipoprotein A-IV mRNA and the close linkage of its gene to the genes of apolipoproteins A-I and C-III.

P31946	1433B_HUMAN	14-3-3 protein beta/alpha	19172738	Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein.

P41996	CPG2_CAEEL	Chondroitin proteoglycan-2	17042944	The eggshell is required for meiotic fidelity, polar-body extrusion and polarization of the C. elegans embryo.

P22748	CAH4_HUMAN	Carbonic anhydrase 4	1311094	Human carbonic anhydrase IV: cDNA cloning, sequence comparison, and expression in COS cell membranes.

Q9UBD6	RHCG_HUMAN	Ammonium transporter Rh type C	15929723	Human Rhesus B and Rhesus C glycoproteins: properties of facilitated ammonium transport in recombinant kidney cells.

O74309	SLM9_SCHPO	Histone transcription regulator slm9	15121850	The Schizosaccharomyces pombe HIRA-like protein Hip1 is required for the periodic expression of histone genes and contributes to the function of complex centromeres.

P36269	GGT5_HUMAN	Gamma-glutamyltransferase 5	1676842	Identification of a human gamma-glutamyl cleaving enzyme related to, but distinct from, gamma-glutamyl transpeptidase.

P16220	CREB1_HUMAN	Cyclic AMP-responsive element-binding protein 1	14506290	Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells.

Q08605	GAGA_DROME	Transcription factor GAGA	15020425	The Drosophila GAGA factor is required for dosage compensation in males and for the formation of the male-specific-lethal complex chromatin entry site at 12DE.

Q90WY5	ADA2B_DANRE	Alpha-2B adrenergic receptor	15655522	Conserved structural, pharmacological and functional properties among the three human and five zebrafish alpha2-adrenoceptors.

Q9C9E3	TI11B_ARATH	Protein TIFY 11B	17637677	JAZ repressor proteins are targets of the SCF(COI1) complex during jasmonate signalling.

P51858	HDGF_HUMAN	Hepatoma-derived growth factor	7929202	Molecular cloning of complementary DNA for a novel human hepatoma- derived growth factor. Its homology with high mobility group-1 protein.

P97756	KKCC1_RAT	Calcium/calmodulin-dependent protein kinase kinase 1	7642608	Characterization of a Ca2+/calmodulin-dependent protein kinase cascade. Molecular cloning and expression of calcium/calmodulin- dependent protein kinase kinase.

Q99996	AKAP9_HUMAN	A-kinase anchor protein 9	9482789	Yotiao, a novel protein of neuromuscular junction and brain that interacts with specific splice variants of NMDA receptor subunit NR1.

Q92973	TNPO1_HUMAN	Transportin-1	10353245	Structure of the nuclear transport complex karyopherin-beta2-Ran x GppNHp.

O01971	EMR1_CAEEL	Emerin homolog 1	12684533	MAN1 and emerin have overlapping function(s) essential for chromosome segregation and cell division in Caenorhabditis elegans.

Q9NRX1	PNO1_HUMAN	RNA-binding protein PNO1	15497447	Cloning and characterization of a novel human RNA binding protein gene PNO1.

Q99933	BAG1_HUMAN	BAG family molecular chaperone regulator 1	11222862	Structure of a Bag/Hsc70 complex: convergent functional evolution of Hsp70 nucleotide exchange factors.

P50591	TNF10_HUMAN	Tumor necrosis factor ligand superfamily member 10	8663110	Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family.

Q9FLT4	AB10A_ARATH	ABC transporter A family member 10	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P32461	DPH2_YEAST	Diphthamide biosynthesis protein 2	8406038	Diphthamide synthesis in Saccharomyces cerevisiae: structure of the DPH2 gene.

P60484	PTEN_HUMAN	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	9811831	The lipid phosphatase activity of PTEN is critical for its tumor supressor function.

P21374	ISY1_YEAST	Pre-mRNA-splicing factor ISY1	11018040	Identification and characterization of two novel components of the Prp19p-associated complex, Ntc30p and Ntc20p.

Q9US49	SGT1_SCHPO	Protein sgt1	16408318	Spsgt1, a new essential gene of Schizosaccharomyces pombe, is involved in carbohydrate metabolism.

Q96KB5	TOPK_HUMAN	Lymphokine-activated killer T-cell-originated protein kinase	10779557	Characterization of PDZ-binding kinase, a mitotic kinase.

O13793	FSF1_SCHPO	Probable mitochondrial transport protein fsf1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9LF53	RGL3_ARATH	DELLA protein RGL3	11826301	Arabidopsis RGL1 encodes a negative regulator of gibberellin responses.

O60053	POF12_SCHPO	F-box protein pof12	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q02796	LGE1_YEAST	Transcriptional regulatory protein LGE1	15528187	Transcriptional regulation by Lge1p requires a function independent of its role in histone H2B ubiquitination.

Q9UK53	ING1_HUMAN	Inhibitor of growth protein 1	8944021	Suppression of the novel growth inhibitor p33ING1 promotes neoplastic transformation.

Q12246	LCB4_YEAST	Sphingoid long chain base kinase 4	9677363	The LCB4 (YOR171c) and LCB5 (YLR260w) genes of Saccharomyces encode sphingoid long chain base kinases.

Q9HCS2	CP4FC_HUMAN	Cytochrome P450 4F12	11162607	cDNA cloning and expression of CYP4F12, a novel human cytochrome P450.

Q9EQW6	OLIG2_MOUSE	Oligodendrocyte transcription factor 2	11955448	Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection.

Q9NRM0	GTR9_HUMAN	Solute carrier family 2, facilitated glucose transporter member 9	10860667	Cloning and expression analysis of a novel member of the facilitative glucose transporter family, SLC2A9 (GLUT9).

Q8TAD4	ZNT5_HUMAN	Zinc transporter 5	11904301	Cloning and characterization of a novel mammalian zinc transporter, zinc transporter 5, abundantly expressed in pancreatic beta cells.

Q12494	KCS1_YEAST	Inositol hexakisphosphate kinase 1	10827188	The inositol hexakisphosphate kinase family. Catalytic flexibility and function in yeast vacuole biogenesis.

Q9LFH5	RL122_ARATH	60S ribosomal protein L12-2	19874541	PYR/PYL/RCAR family members are major in-vivo ABI1 protein phosphatase 2C-interacting proteins in Arabidopsis.

Q03206	RAC1_CAEEL	Ras-related protein ced-10	7677998	A new member of the ras superfamily, the rac1 homologue from Caenorhabditis elegans. Cloning and sequence analysis of cDNA, pattern of developmental expression, and biochemical characterization of the protein.

O14497	ARI1A_HUMAN	AT-rich interactive domain-containing protein 1A	11988099	Cloning and characterization of hELD/OSA1, a novel BRG1 interacting protein.

Q92737	RSLAA_HUMAN	Ras-like protein family member 10A	8975699	Identification of new members of the Gas2 and Ras families in the 22q12 chromosome region.

Q10077	SNT2_SCHPO	Lid2 complex component snt2	12488447	High conservation of the Set1/Rad6 axis of histone 3 lysine 4 methylation in budding and fission yeasts.

Q27451	PRP1_BOMMO	Phenoloxidase subunit 1	7644494	Molecular cloning of insect pro-phenol oxidase: a copper-containing protein homologous to arthropod hemocyanin.

O35841	API5_MOUSE	Apoptosis inhibitor 5	9307294	AAC-11, a novel cDNA that inhibits apoptosis after growth factor withdrawal.

Q8WWR8	NEUR4_HUMAN	Sialidase-4	15213228	Neu4, a novel human lysosomal lumen sialidase, confers normal phenotype to sialidosis and galactosialidosis cells.

Q62172	RBP1_MOUSE	RalA-binding protein 1	8570186	A putative effector of Ral has homology to Rho/Rac GTPase activating proteins.

Q99879	H2B1M_HUMAN	Histone H2B type 1-M	9439656	The human histone gene cluster at the D6S105 locus.

Q9C952	CPSF3_ARATH	Cleavage and polyadenylation specificity factor subunit 3-I	16897494	The 73 kD subunit of the cleavage and polyadenylation specificity factor (CPSF) complex affects reproductive development in Arabidopsis.

Q86W42	THOC6_HUMAN	THO complex subunit 6 homolog	17190602	Human mRNA export machinery recruited to the 5' end of mRNA.

Q9ZVJ3	MA655_ARATH	65-kDa microtubule-associated protein 5	15469496	Molecular dissection of plant cytokinesis and phragmoplast structure: a survey of GFP-tagged proteins.

Q52T38	ZDH22_ARATH	S-acyltransferase TIP1	16100337	The TIP GROWTH DEFECTIVE1 S-acyltransferase regulates plant cell growth in Arabidopsis.

Q96J77	TPD55_HUMAN	Tumor protein D55	16631610	A testis-specific and testis developmentally regulated tumor protein D52 (TPD52)-like protein TPD52L3/hD55 interacts with TPD52 family proteins.

P38935	SMBP2_HUMAN	DNA-binding protein SMUBP-2	8349627	The human S mu bp-2, a DNA-binding protein specific to the single- stranded guanine-rich sequence related to the immunoglobulin mu chain switch region.

P21734	UBC1_YEAST	Ubiquitin-conjugating enzyme E2 1	2265617	UBC1 encodes a novel member of an essential subfamily of yeast ubiquitin-conjugating enzymes involved in protein degradation.

Q9JIY8	CMLO3_MOUSE	Probable N-acetyltransferase CML3	11397015	Overexpression of camello, a member of a novel protein family, reduces blastomere adhesion and inhibits gastrulation in Xenopus laevis.

Q00873	CYT2_YEAST	Cytochrome c1 heme lyase	1499554	Molecular cloning and characterization of the Saccharomyces cerevisiae CYT2 gene encoding cytochrome-c1-heme lyase.

Q8R104	SIRT3_MOUSE	NAD-dependent deacetylase sirtuin-3	11056054	Cloning and characterization of two mouse genes with homology to the yeast sir2 gene.

O49203	NDK3_ARATH	Nucleoside diphosphate kinase III, chloroplastic/mitochondrial	11743114	Proteomic approach to identify novel mitochondrial proteins in Arabidopsis.

Q94131	PIE1_CAEEL	Pharynx and intestine in excess protein 1	8751441	Repression of gene expression in the embryonic germ lineage of C. elegans.

P33759	RT05_YEAST	37S ribosomal protein S5, mitochondrial	11278769	Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues.

O59924	SODC_CANAL	Superoxide dismutase [Cu-Zn]	10216241	Copper- and zinc-containing superoxide dismutase and its gene from Candida albicans.

Q9ZZW7	MBI3_YEAST	Cytochrome b mRNA maturase bI3	11773622	Recruitment of intron-encoded and co-opted proteins in splicing of the bI3 group I intron RNA.

Q5VRY1	HSP18_ORYSJ	18.0 kDa class II heat shock protein	19703271	Rice sHsp genes: genomic organization and expression profiling under stress and development.

O14019	HAL4_SCHPO	Serine/threonine-protein kinase hal4	15821139	Systematic deletion analysis of fission yeast protein kinases.

Q9NZP5	O5AC2_HUMAN	Olfactory receptor 5AC2	10706615	The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates.

Q60I26	AL2CL_MOUSE	ALS2 C-terminal-like protein	15388334	ALS2CL, the novel protein highly homologous to the carboxy-terminal half of ALS2, binds to Rab5 and modulates endosome dynamics.

Q86UW2	OSTB_HUMAN	Organic solute transporter subunit beta	12719432	Functional complementation between a novel mammalian polygenic transport complex and an evolutionarily ancient organic solute transporter, OSTalpha-OSTbeta.

P01137	TGFB1_HUMAN	Transforming growth factor beta-1	17827158	Mechanisms for asporin function and regulation in articular cartilage.

Q8H124	Y2446_ARATH	Uncharacterized protein At2g34460, chloroplastic	16414959	Tocopherol cyclase (VTE1) localization and vitamin E accumulation in chloroplast plastoglobule lipoprotein particles.

O14030	YEM8_SCHPO	Uncharacterized protein C29B12.08	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q05431	APX1_ARATH	L-ascorbate peroxidase 1, cytosolic	15608336	Cytosolic ascorbate peroxidase 1 is a central component of the reactive oxygen gene network of Arabidopsis.

O54949	NLK_MOUSE	Serine/threonine-protein kinase NLK	9448268	Nlk is a murine protein kinase related to Erk/MAP kinases and localized in the nucleus.

P19734	DMPP_PSEUF	Phenol hydroxylase P5 protein	2254258	Complete nucleotide sequence and polypeptide analysis of multicomponent phenol hydroxylase from Pseudomonas sp. strain CF600.

Q9Y5Q5	CORIN_HUMAN	Atrial natriuretic peptide-converting enzyme	10880574	Corin, a transmembrane cardiac serine protease, acts as a pro-atrial natriuretic peptide-converting enzyme.

O42222	GDF8_DANRE	Growth/differentiation factor 8	14555747	Analysis of myostatin gene structure, expression and function in zebrafish.

P69776	LPP_ECOLI	Major outer membrane lipoprotein Lpp	322142	Amino acid sequence for the peptide extension on the prolipoprotein of the Escherichia coli outer membrane.

Q03305	RMT2_YEAST	Arginine N-methyltransferase 2	9873020	S-adenosylmethionine-dependent methylation in Saccharomyces cerevisiae. Identification of a novel protein arginine methyltransferase.

Q63008	SC5A5_RAT	Sodium/iodide cotransporter	8559252	Cloning and characterization of the thyroid iodide transporter.

Q9UJY4	GGA2_HUMAN	ADP-ribosylation factor-binding protein GGA2	10749927	A family of ADP-ribosylation factor effectors that can alter transport through the trans-Golgi.

O14355	YB49_SCHPO	Uncharacterized membrane protein C30D10.09c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9JIY6	CMLO6_RAT	Probable N-acetyltransferase CML6	11397015	Overexpression of camello, a member of a novel protein family, reduces blastomere adhesion and inhibits gastrulation in Xenopus laevis.

Q06109	YP116_YEAST	Uncharacterized protein YPR116W, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

P45895	CHSS2_CAEEL	Chondroitin sulfate synthase 2	15485872	Nematode chondroitin polymerizing factor showing cell-/organ-specific expression is indispensable for chondroitin synthesis and embryonic cell division.

Q12161	PSH1_YEAST	RING finger protein PSH1	14562095	Global analysis of protein localization in budding yeast.

Q9FL28	FLS2_ARATH	LRR receptor-like serine/threonine-protein kinase FLS2	18158241	Pseudomonas syringae effector AvrPto blocks innate immunity by targeting receptor kinases.

O75807	PR15A_HUMAN	Protein phosphatase 1 regulatory subunit 15A	11564868	Growth arrest and DNA damage-inducible protein GADD34 assembles a novel signaling complex containing protein phosphatase 1 and inhibitor 1.

P43681	ACHA4_HUMAN	Neuronal acetylcholine receptor subunit alpha-4	8906617	Comparative structure of human neuronal alpha 2-alpha 7 and beta 2- beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits.

A2BH40	ARI1A_MOUSE	AT-rich interactive domain-containing protein 1A	11318604	Characterization of mammalian orthologues of the Drosophila osa gene: cDNA cloning, expression, chromosomal localization, and direct physical interaction with Brahma chromatin-remodeling complex.

P53314	CPD1_YEAST	2',3'-cyclic-nucleotide 3'-phosphodiesterase	14562095	Global analysis of protein localization in budding yeast.

Q9URV8	YBL3_SCHPO	UPF0744 protein C106.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12060	HFI1_YEAST	Transcriptional coactivator HFI1/ADA1	9674426	A subset of TAF(II)s are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulation.

P58962	GR58A_DROME	Putative gustatory receptor 58a	10710312	Candidate taste receptors in Drosophila.

Q9NEL2	SSL1_CAEEL	Helicase ssl-1	17009877	Temporal regulation of foregut development by HTZ-1/H2A.Z and PHA- 4/FoxA.

Q24342	FNG_DROME	Fringe glycosyltransferase	7954826	Fringe, a boundary-specific signaling molecule, mediates interactions between dorsal and ventral cells during Drosophila wing development.

Q12962	TAF10_HUMAN	Transcription initiation factor TFIID subunit 10	9674425	Histone-like TAFs within the PCAF histone acetylase complex.

Q5BG78	XGEA_EMENI	Xyloglucan-specific endo-beta-1,4-glucanase A	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

P01776	HV315_HUMAN	Ig heavy chain V-III region WAS	4522793	Variable region sequences of five human immunoglobulin heavy chains of the VH3 subgroup: definitive identification of four heavy chain hypervariable regions.

P53267	DAM1_YEAST	DASH complex subunit DAM1	11724818	Functional cooperation of Dam1, Ipl1, and the inner centromere protein (INCENP)-related protein Sli15 during chromosome segregation.

Q8LPK5	CESA8_ARATH	Cellulose synthase A catalytic subunit 8 [UDP-forming]	9165747	Collapsed xylem phenotype of Arabidopsis identifies mutants deficient in cellulose deposition in the secondary cell wall.

P21541	ZYG11_CAEEL	Early embryogenesis protein zyg-11	2325632	Molecular analysis of zyg-11, a maternal-effect gene required for early embryogenesis of Caenorhabditis elegans.

Q12020	SRL2_YEAST	Protein SRL2	14562095	Global analysis of protein localization in budding yeast.

Q8GTR4	PULA1_ARATH	Pullulanase 1, chloroplastic	15849301	Mutants of Arabidopsis lacking a chloroplastic isoamylase accumulate phytoglycogen and an abnormal form of amylopectin.

Q12524	PCD1_YEAST	Peroxisomal coenzyme A diphosphatase 1, peroxisomal	10922370	The Saccharomyces cerevisiae PCD1 gene encodes a peroxisomal nudix hydrolase active toward coenzyme A and its derivatives.

Q9VS48	SLX4_DROME	Structure-specific endonuclease subunit SLX4	19596236	Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases.

Q9UHY1	NRBP_HUMAN	Nuclear receptor-binding protein	11956649	Interaction of the small GTPase Rac3 with NRBP, a protein with a kinase-homology domain.

O43561	LAT_HUMAN	Linker for activation of T-cells family member 1	9489702	LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation.

P35189	TAF14_YEAST	Transcription initiation factor TFIID subunit 14	10817755	The something about silencing protein, Sas3, is the catalytic subunit of NuA3, a yTAF(II)30-containing HAT complex that interacts with the Spt16 subunit of the yeast CP (Cdc68/Pob3)-FACT complex.

Q811T9	DISC1_MOUSE	Disrupted in schizophrenia 1 homolog	19502360	Disc1 regulates granule cell migration in the developing hippocampus.

O15294	OGT1_HUMAN	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit	19377461	GlcNAcylation of a histone methyltransferase in retinoic-acid-induced granulopoiesis.

O13790	CUL1_SCHPO	Cullin-1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P36027	MID2_YEAST	Cell wall integrity sensor MID2	10330137	Mid2 is a putative sensor for cell integrity signaling in Saccharomyces cerevisiae.

Q9JM04	IPO13_RAT	Importin-13	10745026	A novel karyopherin-beta homolog is developmentally and hormonally regulated in fetal lung.

Q9NR34	MA1C1_HUMAN	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC	10915796	Characterization of a cDNA encoding a novel human Golgi alpha 1,2- mannosidase involved in N-glycan biosynthesis.

Q9PUK8	FZD7A_XENLA	Frizzled-7-A	10906785	Interaction of Frizzled 7 and Dishevelled in Xenopus.

P38351	PAF1_YEAST	RNA polymerase II-associated protein 1	15643076	Separation of the Saccharomyces cerevisiae Paf1 complex from RNA polymerase II results in changes in its subnuclear localization.

Q9Z270	VAPA_RAT	Vesicle-associated membrane protein-associated protein A	9920726	Molecular cloning and characterization of mammalian homologues of vesicle-associated membrane protein-associated (VAMP-associated) proteins.

Q9VT57	CDK8_DROME	Cell division protein kinase 8	8730095	Drosophila Cdk8, a kinase partner of cyclin C that interacts with the large subunit of RNA polymerase II.

Q9CXD9	LRC17_MOUSE	Leucine-rich repeat-containing protein 17	19336404	Identification of LRRc17 as a negative regulator of receptor activator of NF-kappaB ligand (RANKL)-induced osteoclast differentiation.

O97178	ESMA_DROME	Enhancer of split malpha protein	10603347	Antagonism of Notch signaling activity by members of a novel protein family encoded by the Bearded and Enhancer of split gene complexes.

P23141	EST1_HUMAN	Liver carboxylesterase 1	8218228	Glycosylation-dependent activity of baculovirus-expressed human liver carboxylesterases: cDNA cloning and characterization of two highly similar enzyme forms.

O74779	MU164_SCHPO	Microtubule-associated protein mug164	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Y6K1	DNM3A_HUMAN	DNA (cytosine-5)-methyltransferase 3A	12138111	A novel Dnmt3a isoform produced from an alternative promoter localizes to euchromatin and its expression correlates with active de novo methylation.

O13612	NEP2_SCHPO	NEDD8-specific protease 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q18409	RSP6_CAEEL	Probable splicing factor, arginine/serine-rich 6	10747030	Functional characterization of SR and SR-related genes in Caenorhabditis elegans.

Q9NS86	LANC2_HUMAN	LanC-like protein 2	16979580	Myristoylation of human LanC-like protein 2 (LANCL2) is essential for the interaction with the plasma membrane and the increase in cellular sensitivity to adriamycin.

P62193	PRS4_RAT	26S protease regulatory subunit 4	8607789	Structures of the rat proteasomal ATPases: determination of highly conserved structural motifs and rules for their spacing.

Q96BM9	ARL8A_HUMAN	ADP-ribosylation factor-like protein 8A	15331635	Novel small GTPase subfamily capable of associating with tubulin is required for chromosome segregation.

Q9QX74	SHAN2_RAT	SH3 and multiple ankyrin repeat domains protein 2	10958799	The G protein-coupled receptor CL1 interacts directly with proteins of the Shank family.

P53114	MED5_YEAST	Mediator of RNA polymerase II transcription subunit 5	9671481	Nuclear proteins Nut1p and Nut2p cooperate to negatively regulate a Swi4p-dependent lacZ reporter gene in Saccharomyces cerevisiae.

Q8IVW6	ARI3B_HUMAN	AT-rich interactive domain-containing protein 3B	10446990	Bdp, a new member of a family of DNA-binding proteins, associates with the retinoblastoma gene product.

O74429	VIP1_SCHPO	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase	10388810	Identification and characterization of Schizosaccharomyces pombe asp1(+), a gene that interacts with mutations in the Arp2/3 complex and actin.

Q9SAR5	AKR2_ARATH	Ankyrin repeat domain-containing protein 2	11862948	An ankyrin repeat-containing protein plays a role in both disease resistance and antioxidation metabolism.

Q8BPU7	ELMO1_MOUSE	Engulfment and cell motility protein 1	11595183	CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration.

P58428	ABCG8_RAT	ATP-binding cassette sub-family G member 8	11452359	Two genes that map to the STSL locus cause sitosterolemia: genomic structure and spectrum of mutations involving sterolin-1 and sterolin- 2, encoded by ABCG5 and ABCG8, respectively.

P51592	HYD_DROME	E3 ubiquitin-protein ligase hyd	7958417	Genetic and molecular analysis of hyperplastic discs, a gene whose product is required for regulation of cell proliferation in Drosophila melanogaster imaginal discs and germ cells.

Q800K6	TOB1A_XENLA	DNA topoisomerase 2-binding protein 1-A	16530042	TopBP1 activates the ATR-ATRIP complex.

P38851	YSP1_YEAST	Protein YSP1	14562095	Global analysis of protein localization in budding yeast.

P67809	YBOX1_HUMAN	Nuclease-sensitive element-binding protein 1	8188694	A human protein containing a 'cold shock' domain binds specifically to H-DNA upstream from the human gamma-globin genes.

Q13585	MTR1L_HUMAN	Melatonin-related receptor	8647286	Cloning of a melatonin-related receptor from human pituitary.

A2ARP9	CTSR2_MOUSE	Cation channel sperm-associated protein 2	14657366	Hyperactivated sperm motility driven by CatSper2 is required for fertilization.

P40339	RFC4_YEAST	Replication factor C subunit 4	11486023	Chl12 (Ctf18) forms a novel replication factor C-related complex and functions redundantly with Rad24 in the DNA replication checkpoint pathway.

P38682	GLO3_YEAST	ADP-ribosylation factor GTPase-activating protein GLO3	9927415	Retrograde transport from the yeast Golgi is mediated by two ARF GAP proteins with overlapping function.

Q04341	MIC14_YEAST	Mitochondrial intermembrane space cysteine motif-containing protein MIC14	17095012	Novel mitochondrial intermembrane space proteins as substrates of the MIA import pathway.

Q06587	RING1_HUMAN	E3 ubiquitin-protein ligase RING1	9199346	RING1 is associated with the polycomb group protein complex and acts as a transcriptional repressor.

Q9JMI0	ECEL1_MOUSE	Endothelin-converting enzyme-like 1	10759559	Damage-induced neuronal endopeptidase (DINE) is a unique metallopeptidase expressed in response to neuronal damage and activates superoxide scavengers.

P38803	IPI1_YEAST	Pre-rRNA-processing protein IPI1	14690591	Assigning function to yeast proteins by integration of technologies.

Q22560	IMA1_CAEEL	Importin subunit alpha-1	11311162	Germline and developmental roles of the nuclear transport factor importin alpha3 in C. elegans.

Q9UT53	NMAH_SCHPO	Putative nicotinamide-nucleotide adenylyltransferase C806.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q07990	YL042_YEAST	Cell wall protein YLR042C	10383953	Amino acid residues in the omega-minus region participate in cellular localization of yeast glycosylphosphatidylinositol-attached proteins.

Q02770	CWC27_YEAST	Peptidyl-prolyl isomerase CWC27	11884590	Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

Q9C6L5	KCS5_ARATH	3-ketoacyl-CoA synthase 5	15277688	Specific and differential inhibition of very-long-chain fatty acid elongases from Arabidopsis thaliana by different herbicides.

Q38906	TOC34_ARATH	Translocase of chloroplast 34, chloroplastic	12766230	Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.

P32389	MET4_YEAST	Transcriptional activator of sulfur metabolism MET4	10637232	Feedback-regulated degradation of the transcriptional activator Met4 is triggered by the SCF(Met30) complex.

Q07750	ADF1_CAEEL	Actin-depolymerizing factor 1, isoforms a/b	8107682	The Caenorhabditis elegans unc-60 gene encodes proteins homologous to a family of actin-binding proteins.

P40492	FYV10_YEAST	Protein FYV10	14562095	Global analysis of protein localization in budding yeast.

Q03173	ENAH_MOUSE	Protein enabled homolog	12672821	Abl interactor 1 promotes tyrosine 296 phosphorylation of mammalian enabled (Mena) by c-Abl kinase.

Q6ZMZ0	RN19B_HUMAN	E3 ubiquitin-protein ligase RNF19B	16709802	NK lytic-associated molecule, involved in NK cytotoxic function, is an E3 ligase.

Q24368	ISWI_DROME	Chromatin-remodeling complex ATPase chain Iswi	12502740	Biological functions of the ISWI chromatin remodeling complex NURF.

Q9P0K1	ADA22_HUMAN	Disintegrin and metalloproteinase domain-containing protein 22	9693107	Metalloproteinase-like, disintegrin-like, cysteine-rich proteins MDC2 and MDC3: novel human cellular disintegrins highly expressed in the brain.

P53955	SLM2_YEAST	Phosphatidylinositol 4,5-bisphosphate-binding protein SLM2	15372071	Genome-wide lethality screen identifies new PI4,5P2 effectors that regulate the actin cytoskeleton.

Q9NYL2	MLTK_HUMAN	Mitogen-activated protein kinase kinase kinase MLT	11836244	MRK, a mixed lineage kinase-related molecule that plays a role in gamma-radiation-induced cell cycle arrest.

P27048	RSMB_MOUSE	Small nuclear ribonucleoprotein-associated protein B	19470752	Three proteins of the U7-specific Sm ring function as the molecular ruler to determine the site of 3'-end processing in mammalian histone pre-mRNA.

P52793	EFNA1_MOUSE	Ephrin-A1	16782872	Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis.

P14921	ETS1_HUMAN	Protein C-ets-1	10698492	EAP1/Daxx interacts with ETS1 and represses transcriptional activation of ETS1 target genes.

Q9NVC6	MED17_HUMAN	Mediator of RNA polymerase II transcription subunit 17	9989412	The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1.

Q9NUT2	ABCB8_HUMAN	ATP-binding cassette sub-family B member 8, mitochondrial	9878413	Identification and characterization of a mammalian mitochondrial ATP- binding cassette membrane protein.

Q9C0H2	TTYH3_HUMAN	Protein tweety homolog 3	15010458	A novel human Cl(-) channel family related to Drosophila flightless locus.

O61443	MK14B_DROME	Mitogen-activated protein kinase 14B	10022918	p38 mitogen-activated protein kinase can be involved in transforming growth factor beta superfamily signal transduction in Drosophila wing morphogenesis.

Q9CWR0	ARHGP_MOUSE	Rho guanine nucleotide exchange factor 25	18541910	Bves directly interacts with GEFT, and controls cell shape and movement through regulation of Rac1/Cdc42 activity.

P14046	A1I3_RAT	Alpha-1-inhibitor 3	2831216	Sequence and acute phase regulation of rat alpha 1-inhibitor III messenger RNA.

P32074	COPG_YEAST	Coatomer subunit gamma	1461285	SEC21 is a gene required for ER to Golgi protein transport that encodes a subunit of a yeast coatomer.

P41133	ID3_MOUSE	DNA-binding protein inhibitor ID-3	2000388	An Id-related helix-loop-helix protein encoded by a growth factor- inducible gene.

Q04980	LTI65_ARATH	Low-temperature-induced 65 kDa protein	8448363	Differential expression of two related, low-temperature-induced genes in Arabidopsis thaliana (L.) Heynh.

Q24572	CAF1_DROME	Probable histone-binding protein Caf1	12490953	Role for a Drosophila Myb-containing protein complex in site-specific DNA replication.

Q9Y2Q0	AT8A1_HUMAN	Probable phospholipid-transporting ATPase IA	10198212	Cloning, expression, and chromosomal mapping of a human ATPase II gene, member of the third subfamily of P-type ATPases and orthologous to the presumed bovine and murine aminophospholipid translocase.

Q32P28	P3H1_HUMAN	Prolyl 3-hydroxylase 1	10951563	Gros1, a potential growth suppressor on chromosome 1: its identity to basement membrane-associated proteoglycan, leprecan.

P10275	ANDR_HUMAN	Androgen receptor	10075738	Cloning and characterization of androgen receptor coactivator, ARA55, in human prostate.

Q63340	DUS7_RAT	Dual specificity protein phosphatase 7	8626780	MKP-3, a novel cytosolic protein-tyrosine phosphatase that exemplifies a new class of mitogen-activated protein kinase phosphatase.

Q9NP98	MYOZ1_HUMAN	Myozenin-1	11114196	Calsarcins, a novel family of sarcomeric calcineurin-binding proteins.

Q03346	MPPB_RAT	Mitochondrial-processing peptidase subunit beta	8506385	The beta subunit of the mitochondrial processing peptidase from rat liver: cloning and sequencing of a cDNA and comparison with a proposed family of metallopeptidases.

Q9V4P1	ANLN_DROME	Actin-binding protein anillin	12134082	Molecular dissection of cytokinesis by RNA interference in Drosophila cultured cells.

Q13352	CENPR_HUMAN	Centromere protein R	10490654	NRIF3 is a novel coactivator mediating functional specificity of nuclear hormone receptors.

O80982	HSFA2_ARATH	Heat stress transcription factor A-2	20521085	Sumoylation of Arabidopsis heat shock factor A2 (HsfA2) modifies its activity during acquired thermotholerance.

Q9UT63	YKJ2_SCHPO	Probable phosphoglycerate mutase C513.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P67775	PP2AA_HUMAN	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform	16541025	Shugoshin collaborates with protein phosphatase 2A to protect cohesin.

P41250	SYG_HUMAN	Glycyl-tRNA synthetase	7961834	Primary structure and functional expression of human glycyl-tRNA synthetase, an autoantigen in myositis.

Q8CGN5	PLIN1_MOUSE	Perilipin-1	15292255	Perilipin A mediates the reversible binding of CGI-58 to lipid droplets in 3T3-L1 adipocytes.

P86095	NXS1_MICSU	Short neurotoxin MS1	18384102	Proteomic analysis of the venom from the fish eating coral snake Micrurus surinamensis: novel toxins, their function and phylogeny.

O89000	DPYD_RAT	Dihydropyrimidine dehydrogenase [NADP+]	9819714	Cloning of rat dihydropyrimidine dehydrogenase and correlation of its mRNA increase in the rat liver with age.

Q9U2Q9	GSK3_CAEEL	Glycogen synthase kinase-3	17601533	Two functionally distinct axin-like proteins regulate canonical Wnt signaling in C. elegans.

Q80Y17	L2GL1_MOUSE	Lethal(2) giant larvae protein homolog 1	15037549	Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice.

Q9QXU9	PCSK1_RAT	ProSAAS	11742530	Processing of proSAAS in neuroendocrine cell lines.

P85870	DCRLN_OREDC	Decoralin	17981364	Decoralin, a novel linear cationic alpha-helical peptide from the venom of the solitary eumenine wasp Oreumenes decoratus.

Q63285	UHMK1_RAT	Serine/threonine-protein kinase Kist	8910496	Novel proteins that interact with the COOH-terminal cytosolic routing determinants of an integral membrane peptide-processing enzyme.

Q9Z261	CLD7_MOUSE	Claudin-7	9892664	Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands.

P33767	OSTB_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1	16297388	Yeast oligosaccharyltransferase consists of two functionally distinct sub-complexes, specified by either the Ost3p or Ost6p subunit.

Q70IV5	SYNEM_MOUSE	Synemin	15265691	The mouse synemin gene encodes three intermediate filament proteins generated by alternative exon usage and different open reading frames.

O95178	NDUB2_HUMAN	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

P13765	DOB_HUMAN	HLA class II histocompatibility antigen, DO beta chain	2998758	DO beta: a new beta chain gene in HLA-D with a distinct regulation of expression.

P47140	AIM25_YEAST	Altered inheritance rate of mitochondria protein 25	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

P11632	NHP6A_YEAST	Non-histone chromosomal protein 6A	8946917	Yeast HMG proteins NHP6A/B potentiate promoter-specific transcriptional activation in vivo and assembly of preinitiation complexes in vitro.

Q8CJ40	CROCC_MOUSE	Rootletin	12427867	Rootletin, a novel coiled-coil protein, is a structural component of the ciliary rootlet.

P16104	H2AX_HUMAN	Histone H2A.x	12607005	MDC1 is a mediator of the mammalian DNA damage checkpoint.

Q16558	KCMB1_HUMAN	Calcium-activated potassium channel subunit beta-1	8799178	Cloning, expression, and distribution of a Ca(2+)-activated K+ channel beta-subunit from human brain.

Q8VWG7	TDX_ARATH	TPR repeat-containing thioredoxin TDX	19293385	Heat-shock dependent oligomeric status alters the function of a plant-specific thioredoxin-like protein, AtTDX.

P23614	BASP1_CHICK	Brain acid soluble protein 1 homolog	2148567	Identification, localization, and primary structure of CAP-23, a particle-bound cytosolic protein of early development.

Q00P32	HES2_XENLA	Transcription factor HES-2	15531363	Sequences downstream of the bHLH domain of the Xenopus hairy-related transcription factor-1 act as an extended dimerization domain that contributes to the selection of the partners.

Q15849	UT2_HUMAN	Urea transporter 2	17702749	The UT-A1 urea transporter interacts with snapin, a SNARE-associated protein.

O35437	TCF21_MOUSE	Transcription factor 21	10572052	The basic-helix-loop-helix protein pod1 is critically important for kidney and lung organogenesis.

Q99NA9	PCGF6_MOUSE	Polycomb group RING finger protein 6	12167161	MBLR, a new RING finger protein resembling mammalian Polycomb gene products, is regulated by cell cycle-dependent phosphorylation.

P61978	HNRPK_HUMAN	Heterogeneous nuclear ribonucleoprotein K	8107114	Identification, molecular cloning, expression and chromosome mapping of a family of transformation upregulated hnRNP-K proteins derived by alternative splicing.

O00533	CHL1_HUMAN	Neural cell adhesion molecule L1-like protein	9799093	In silico-initiated cloning and molecular characterization of a novel human member of the L1 gene family of neural cell adhesion molecules.

P25335	ALLC_YEAST	Allantoicase	1916277	Sequences of two adjacent genes, one (DAL2) encoding allantoicase and another (DCG1) sensitive to nitrogen-catabolite repression in Saccharomyces cerevisiae.

P38273	CCZ1_YEAST	Vacuolar fusion protein CCZ1	11069774	The novel protein Ccz1p required for vacuolar assembly in Saccharomyces cerevisiae functions in the same transport pathway as Ypt7p.

P32597	STH1_YEAST	Nuclear protein STH1/NPS1	9154831	Sfh1p, a component of a novel chromatin-remodeling complex, is required for cell cycle progression.

P50519	HSP9_SCHPO	Heat shock protein hsp9	8654972	Isolation of an HSP12-homologous gene of Schizosaccharomyces pombe suppressing a temperature-sensitive mutant allele of cdc4.

P23250	RPI1_YEAST	Negative RAS protein regulator protein	1649384	Overexpression of RPI1, a novel inhibitor of the yeast Ras-cyclic AMP pathway, down-regulates normal but not mutationally activated ras function.

Q9M9S2	PLY3_ARATH	Probable pectate lyase 3	9278171	Identification of the tobacco and Arabidopsis homologues of the pollen-expressed LAT59 gene of tomato.

Q944Q0	WNK8_ARATH	Serine/threonine-protein kinase WNK8	12506983	Compilation and characterization of a novel WNK family of protein kinases in Arabiodpsis thaliana with reference to circadian rhythms.

P20339	RAB5A_HUMAN	Ras-related protein Rab-5A	15378032	Structural basis of Rab5-Rabaptin5 interaction in endocytosis.

Q9C5C8	MSRB2_ARATH	Peptide methionine sulfoxide reductase B2, chloroplastic	15923321	The Arabidopsis plastidic methionine sulfoxide reductase B proteins. Sequence and activity characteristics, comparison of the expression with plastidic methionine sulfoxide reductase A, and induction by photooxidative stress.

Q10482	STM1_SCHPO	Seven transmembrane protein 1	11461899	Isolation of a novel gene from Schizosaccharomyces pombe: stm1+ encoding a seven-transmembrane loop protein that may couple with the heterotrimeric Galpha 2 protein, Gpa2.

P56975	NRG3_HUMAN	Pro-neuregulin-3, membrane-bound isoform	9275162	Neuregulin-3 (NRG3): a novel neural tissue-enriched protein that binds and activates ErbB4.

O00592	PODXL_HUMAN	Podocalyxin	9188463	Molecular cloning and characterization of human podocalyxin-like protein. Orthologous relationship to rabbit PCLP1 and rat podocalyxin.

O88491	NSD1_MOUSE	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific	15169884	Nizp1, a novel multitype zinc finger protein that interacts with the NSD1 histone lysine methyltransferase through a unique C2HR motif.

P47940	RES18_RAT	Regulated endocrine-specific protein 18	8132649	RESP18, a novel endocrine secretory protein transcript, and four other transcripts are regulated in parallel with pro-opiomelanocortin in melanotropes.

O43038	VPS36_SCHPO	Vacuolar protein-sorting-associated protein 36	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P17512	MT2_CAEEL	Metallothionein-2	8428932	The novel metallothionein genes of Caenorhabditis elegans. Structural organization and inducible, cell-specific expression.

Q96WN6	ACE2_TRIRE	Transcription factor ACEII	11304525	ACEII, a novel transcriptional activator involved in regulation of cellulase and xylanase genes of Trichoderma reesei.

Q9YH09	RALBA_XENLA	Ras-related protein ralB-A	9753634	Identification and characterization in Xenopus of XsmgGDS, a RalB- binding protein.

P39083	RGA1_YEAST	Rho-type GTPase-activating protein 1	8657111	The LIM domain-containing Dbm1 GTPase-activating protein is required for normal cellular morphogenesis in Saccharomyces cerevisiae.

P42582	NKX25_MOUSE	Homeobox protein Nkx-2.5	9748262	Homeodomain-interacting protein kinases, a novel family of co- repressors for homeodomain transcription factors.

P53259	PCP1_YEAST	Rhomboid protein 1, mitochondrial	11907266	Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae.

P12504	VIF_HV1N5	Virion infectivity factor	11278465	The tyrosine kinase Hck is an inhibitor of HIV-1 replication counteracted by the viral vif protein.

P25579	LRE1_YEAST	Laminarase-resistance protein LRE1	11580836	Lre1 affects chitinase expression, trehalose accumulation and heat resistance through inhibition of the Cbk1 protein kinase in Saccharomyces cerevisiae.

Q9NYQ2	HAOX2_MOUSE	Hydroxyacid oxidase 2	10777549	Identification and characterization of HAOX1, HAOX2, and HAOX3, three human peroxisomal 2-hydroxy acid oxidases.

O95671	ASML_HUMAN	N-acetylserotonin O-methyltransferase-like protein	9736779	Gene duplications as a recurrent theme in the evolution of the human pseudoautosomal region 1: isolation of the gene ASMTL.

P38310	FTH1_YEAST	Iron transporter FTH1	10608875	The iron transporter Fth1p forms a complex with the Fet5 iron oxidase and resides on the vacuolar membrane.

Q6ZU15	SEP14_HUMAN	Septin-14	17922164	Characterization of a SEPT9 interacting protein, SEPT14, a novel testis-specific septin.

O14008	CAM2_SCHPO	Myosin 1 light chain cam2	17202724	Localization of type I myosin and F-actin to the leading edge region of the forespore membrane in Schizosaccharomyces pombe.

A2AQ25	SKT_MOUSE	Sickle tail protein	16204209	A novel murine gene, Sickle tail, linked to the Danforth's short tail locus, is required for normal development of the intervertebral disc.

Q08773	ISW2_YEAST	ISWI chromatin-remodeling complex ATPase ISW2	14673157	Noncompetitive counteractions of DNA polymerase epsilon and ISW2/yCHRAC for epigenetic inheritance of telomere position effect in Saccharomyces cerevisiae.

A2ARP9	CTSR2_MOUSE	Cation channel sperm-associated protein 2	11675491	A voltage-gated ion channel expressed specifically in spermatozoa.

P06309	KV205_HUMAN	Ig kappa chain V-II region GM607	6325927	Contribution of human V kappa II germ-line genes to light-chain diversity.

P24298	ALAT1_HUMAN	Alanine aminotransferase 1	1931970	Complete amino acid sequence of human liver cytosolic alanine aminotransferase (GPT) determined by a combination of conventional and mass spectral methods.

Q06287	EMG1_YEAST	Essential for mitotic growth 1	11935223	Nep1p (Emg1p), a novel protein conserved in eukaryotes and archaea, is involved in ribosome biogenesis.

Q8K558	TRML1_MOUSE	Trem-like transcript 1 protein	12393607	Initial characterization of TREM-like transcript (TLT)-1: a putative inhibitory receptor within the TREM cluster.

P31749	AKT1_HUMAN	RAC-alpha serine/threonine-protein kinase	8978681	Mechanism of activation of protein kinase B by insulin and IGF-1.

Q8BFW3	PR15B_MOUSE	Protein phosphatase 1 regulatory subunit 15B	14638860	Inhibition of a constitutive translation initiation factor 2alpha phosphatase, CReP, promotes survival of stressed cells.

Q9C5X4	ATX1_ARATH	Histone-lysine N-methyltransferase ATX1	12699618	ATX-1, an Arabidopsis homolog of trithorax, activates flower homeotic genes.

Q9ZVH4	CUL3A_ARATH	Cullin-3A	15659098	Molecular and functional characterization of Arabidopsis Cullin 3A.

Q8L770	CLPR3_ARATH	ATP-dependent Clp protease proteolytic subunit-related protein 3, chloroplastic	14593120	Clp protease complexes from photosynthetic and non-photosynthetic plastids and mitochondria of plants, their predicted three-dimensional structures, and functional implications.

Q92934	BAD_HUMAN	Bcl2 antagonist of cell death	9388232	Dimerization properties of human BAD. Identification of a BH-3 domain and analysis of its binding to mutant BCL-2 and BCL-XL proteins.

P10242	MYB_HUMAN	Transcriptional activator Myb	2189102	Transcriptional activation by human c-myb and v-myb genes.

P47083	MPP10_YEAST	U3 small nucleolar RNA-associated protein MPP10	12068309	A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis.

Q9FYK5	ESR2_ARATH	Ethylene-responsive transcription factor ESR2	17376809	The AP2 transcription factors DORNROSCHEN and DORNROSCHEN-LIKE redundantly control Arabidopsis embryo patterning via interaction with PHAVOLUTA.

Q12018	CDC53_YEAST	Cell division control protein 53	9736614	The Cdc42p effector Gic2p is targeted for ubiquitin-dependent degradation by the SCFGrr1 complex.

Q9RY80	DDRB_DEIRA	Single-stranded DNA-binding protein DdrB	19515845	DdrB protein, an alternative Deinococcus radiodurans SSB induced by ionizing radiation.

Q7XA73	TIF4A_ARATH	Protein TIFY 4A	16916932	PEAPOD regulates lamina size and curvature in Arabidopsis.

P40547	VID28_YEAST	Vacuolar import and degradation protein 28	12686616	Catabolite degradation of fructose-1,6-bisphosphatase in the yeast Saccharomyces cerevisiae: a genome-wide screen identifies eight novel GID genes and indicates the existence of two degradation pathways.

Q02790	FKBP4_HUMAN	Peptidyl-prolyl cis-trans isomerase FKBP4	1279700	Expression and characterization of human FKBP52, an immunophilin that associates with the 90-kDa heat shock protein and is a component of steroid receptor complexes.

Q54PQ4	GEFA_DICDI	Ras guanine nucleotide exchange factor A	17380187	Cyclic AMP signalling in Dictyostelium: G-proteins activate separate Ras pathways using specific RasGEFs.

P27133	COROA_DICDI	Coronin-A	1661669	Coronin, an actin binding protein of Dictyostelium discoideum localized to cell surface projections, has sequence similarities to G protein beta subunits.

Q96LW7	BINCA_HUMAN	Bcl10-interacting CARD protein	15637807	Inhibition of Bcl10-mediated activation of NF-kappa B by BinCARD, a Bcl10-interacting CARD protein.

Q9V3A4	CSUP_DROME	Protein catecholamines up	10471719	The catecholamines up (Catsup) protein of Drosophila melanogaster functions as a negative regulator of tyrosine hydroxylase activity.

P50108	MNN10_YEAST	Probable alpha-1,6-mannosyltransferase MNN10	10037752	The Saccharomyces cerevisiae protein Mnn10p/Bed1p is a subunit of a Golgi mannosyltransferase complex.

Q9FKS8	LHT1_ARATH	Lysine histidine transporter 1	16816136	Arabidopsis LHT1 is a high-affinity transporter for cellular amino acid uptake in both root epidermis and leaf mesophyll.

P38967	TAT2_YEAST	Tryptophan permease	10654085	Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae.

P43652	AFAM_HUMAN	Afamin	7517938	Afamin is a new member of the albumin, alpha-fetoprotein, and vitamin D-binding protein gene family.

P64797	Y1284_MYCTU	Putative carbonate dehydratase-like protein Rv1284	15753099	Structure and function of carbonic anhydrases from Mycobacterium tuberculosis.

P05090	APOD_HUMAN	Apolipoprotein D	3453108	Cloning and expression of human apolipoprotein D cDNA.

P26431	SL9A1_RAT	Sodium/hydrogen exchanger 1	18321853	Calcineurin B homologous protein 3 promotes the biosynthetic maturation, cell surface stability, and optimal transport of the Na+/H+ exchanger NHE1 isoform.

P13501	CCL5_HUMAN	C-C motif chemokine 5	1380064	Cytokine RANTES released by thrombin-stimulated platelets is a potent attractant for human eosinophils.

P19541	RDS2_YEAST	Regulator of drug sensitivity 2	17875938	Regulation of gluconeogenesis in Saccharomyces cerevisiae is mediated by activator and repressor functions of Rds2.

Q8JZQ0	CSF1_RAT	Macrophage colony-stimulating factor 1	12074592	Mutation of macrophage colony stimulating factor (Csf1) causes osteopetrosis in the tl rat.

P16871	IL7RA_HUMAN	Interleukin-7 receptor subunit alpha	9843216	Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency.

P28004	PRP45_YEAST	Pre-mRNA-processing protein 45	12554883	Identification and characterization of Prp45p and Prp46p, essential pre-mRNA splicing factors.

Q62786	FPRP_RAT	Prostaglandin F2 receptor negative regulator	8804121	Negative regulatory activity of a prostaglandin F2 alpha receptor associated protein (FPRP).

Q9R229	BMP10_MOUSE	Bone morphogenetic protein 10	10072785	Heart specific expression of mouse BMP-10 a novel member of the TGF- beta superfamily.

Q7TT49	MRCKB_RAT	Serine/threonine-protein kinase MRCK beta	9418861	Myotonic dystrophy kinase-related Cdc42-binding kinase acts as a Cdc42 effector in promoting cytoskeletal reorganization.

Q9EQG6	KDIS_RAT	Kinase D-interacting substrate of 220 kDa	15167895	A unique pathway for sustained neurotrophin signaling through an ankyrin-rich membrane-spanning protein.

Q9ES30	C1QT3_MOUSE	Complement C1q tumor necrosis factor-related protein 3	11071891	Molecular cloning and characterization of a novel gene, CORS26, encoding a putative secretory protein and its possible involvement in skeletal development.

P02751	FINC_HUMAN	Fibronectin	3024962	Mapping the collagen-binding site of human fibronectin by expression in Escherichia coli.

Q61762	KCNA5_MOUSE	Potassium voltage-gated channel subfamily A member 5	8226976	Multiple mRNA isoforms encoding the mouse cardiac Kv1-5 delayed rectifier K+ channel.

O13657	YBCC_SCHPO	Putative metal ion transporter C27B12.12c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9BXW9	FACD2_HUMAN	Fanconi anemia group D2 protein	12874027	Menin associates with FANCD2, a protein involved in repair of DNA damage.

P34278	KNL1_CAEEL	Kinetochore null protein 1	15767665	HCP-4/CENP-C promotes the prophase timing of centromere resolution by enabling the centromere association of HCP-6 in Caenorhabditis elegans.

P78406	RAE1L_HUMAN	mRNA export factor	9256445	mRNA binding protein mrnp 41 localizes to both nucleus and cytoplasm.

Q86YS3	RFIP4_HUMAN	Rab11 family-interacting protein 4	16148947	Rab11-FIP3 and FIP4 interact with Arf6 and the exocyst to control membrane traffic in cytokinesis.

Q9FRL8	DHAR2_ARATH	Glutathione S-transferase DHAR2	15159623	Proteomic analysis of glutathione S -transferases of Arabidopsis thaliana reveals differential salicylic acid-induced expression of the plant-specific phi and tau classes.

O94751	BUB1_SCHPO	Checkpoint serine/threonine-protein kinase bub1	15525673	The A78V mutation in the Mad3-like domain of Schizosaccharomyces pombe Bub1p perturbs nuclear accumulation and kinetochore targeting of Bub1p, Bub3p, and Mad3p and spindle assembly checkpoint function.

P75990	YCGF_ECOLI	Blue light- and temperature-regulated antirepressor YcgF	19240136	The BLUF-EAL protein YcgF acts as a direct anti-repressor in a blue- light response of Escherichia coli.

Q8VHK6	I13R2_RAT	Interleukin-13 receptor subunit alpha-2	12241113	Molecular cloning of the rat IL-13 alpha 2 receptor cDNA and its expression in rat tissues.

Q0QWG9	GRD2I_MOUSE	Delphilin	11826110	Delphilin: a novel PDZ and formin homology domain-containing protein that synaptically colocalizes and interacts with glutamate receptor delta 2 subunit.

Q5VRD1	IAA1_ORYSJ	Auxin-responsive protein IAA1	16200395	Structure and expression analysis of early auxin-responsive Aux/IAA gene family in rice (Oryza sativa).

O75223	GGCT_HUMAN	Gamma-glutamylcyclotransferase	16765912	A novel 21-kDa cytochrome c-releasing factor is generated upon treatment of human leukemia U937 cells with geranylgeraniol.

Q1JQ73	ELV1A_XENLA	ELAV-like protein 1-A	9343402	The 36-kilodalton embryonic-type cytoplasmic polyadenylation element- binding protein in Xenopus laevis is ElrA, a member of the ELAV family of RNA-binding proteins.

Q9LPL4	SKP2A_ARATH	F-box protein SKP2A	12468727	Arabidopsis E2Fc functions in cell division and is degraded by the ubiquitin-SCF(AtSKP2) pathway in response to light.

Q13608	PEX6_HUMAN	Peroxisome assembly factor 2	8940266	Human peroxisome assembly factor-2 (PAF-2): a gene responsible for group C peroxisome biogenesis disorder in humans.

P61225	RAP2B_HUMAN	Ras-related protein Rap-2b	2118648	RAP2B: a RAS-related GTP-binding protein from platelets.

Q27368	E2F_DROME	Transcription factor E2f	9271122	Mutations in Drosophila DP and E2F distinguish G1-S progression from an associated transcriptional program.

O80689	BGL45_ARATH	Beta-glucosidase 45	16814332	Arabidopsis thaliana beta-glucosidases BGLU45 and BGLU46 hydrolyse monolignol glucosides.

Q8WYN0	ATG4A_HUMAN	Cysteine protease ATG4A	12473658	The COOH terminus of GATE-16, an intra-Golgi transport modulator, is cleaved by the human cysteine protease HsApg4A.

Q15785	TOM34_HUMAN	Mitochondrial import receptor subunit TOM34	9660753	Specific binding of tetratricopeptide repeat proteins to the C- terminal 12-kDa domain of hsp90.

Q38872	CDPK6_ARATH	Calcium-dependent protein kinase 6	17032064	CDPKs CPK6 and CPK3 function in ABA regulation of guard cell S-type anion-and Ca(2+)-permeable channels and stomatal closure.

P01762	HV301_HUMAN	Ig heavy chain V-III region TRO	809331	The primary structure of a monoclonal IgA-immunoglobulin (IgA Tro.), II. The amino acid sequence of the H-chain, alpha-type, subgroup III; structure of the complete IgA-molecule.

P36116	VPS51_YEAST	Vacuolar protein sorting-associated protein 51	12134085	Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae.

P70662	LDB1_MOUSE	LIM domain-binding protein 1	10393337	A brain region-specific gene product Lhx6.1 interacts with Ldb1 through tandem LIM-domains.

Q02796	LGE1_YEAST	Transcriptional regulatory protein LGE1	12089449	Systematic identification of pathways that couple cell growth and division in yeast.

P02751	FINC_HUMAN	Fibronectin	7989369	Further characterization of the NH2-terminal fibrin-binding site on fibronectin.

O35552	F263_RAT	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	9202288	Novel isoforms of rat brain fructose 6-phosphate 2-kinase/fructose 2,6-bisphosphatase are generated by tissue-specific alternative splicing.

Q9Y2U8	MAN1_HUMAN	Inner nuclear membrane protein Man1	15647271	The integral inner nuclear membrane protein MAN1 physically interacts with the R-Smad proteins to repress signaling by the transforming growth factor-{beta} superfamily of cytokines.

P84815	PTYA_RANSV	Peptide tyrosine arginine	15808903	Peptide tyrosine arginine, a potent immunomodulatory peptide isolated and structurally characterized from the skin secretions of the dusky gopher frog, Rana sevosa.

Q01389	BCK1_YEAST	Serine/threonine-protein kinase BCK1/SLK1/SSP31	1545797	A synthetic lethal screen identifies SLK1, a novel protein kinase homolog implicated in yeast cell morphogenesis and cell growth.

P78963	SKB1_SCHPO	Protein arginine N-methyltransferase skb1	11278267	The highly conserved protein methyltransferase, Skb1, is a mediator of hyperosmotic stress response in the fission yeast Schizosaccharomyces pombe.

P17608	RYH1_SCHPO	GTP-binding protein ryh1	2112088	The ryh1 gene in the fission yeast Schizosaccharomyces pombe encoding a GTP-binding protein related to ras, rho and ypt: structure, expression and identification of its human homologue.

Q6WNK7	SUS1_YEAST	Protein SUS1	16855026	The mRNA export factor Sus1 is involved in Spt/Ada/Gcn5 acetyltransferase-mediated H2B deubiquitinylation through its interaction with Ubp8 and Sgf11.

O84947	SSEC_SALTY	Secreted effector protein sseC	11567004	SseBCD proteins are secreted by the type III secretion system of Salmonella pathogenicity island 2 and function as a translocon.

O15287	FANCG_HUMAN	Fanconi anemia group G protein	9256465	The human XRCC9 gene corrects chromosomal instability and mutagen sensitivities in CHO UV40 cells.

O93464	CCKN_CARAU	Cholecystokinin	8262360	CCK/gastrin-like immunoreactivity in the goldfish pituitary: regulation of pituitary hormone secretion by CCK-like peptides in vitro.

P50520	VPS34_SCHPO	Phosphatidylinositol 3-kinase vps34	8719881	Schizosaccharomyces pombe Vps34p, a phosphatidylinositol-specific PI 3-kinase essential for normal cell growth and vacuole morphology.

P51610	HCFC1_HUMAN	Host cell factor 1	14532282	HCF-1 functions as a coactivator for the zinc finger protein Krox20.

O43189	PHF1_HUMAN	PHD finger protein 1	9545646	The identification and localization of a human gene with sequence similarity to Polycomblike of Drosophila melanogaster.

P53933	APP1_YEAST	Actin patch protein 1	11489916	A protein interaction map for cell polarity development.

Q54F46	WARA_DICDI	Homeobox protein Wariai	9486804	The homeobox-containing gene Wariai regulates anterior-posterior patterning and cell-type homeostasis in Dictyostelium.

P53223	CAX4_YEAST	Dolichyldiphosphatase	10024662	The Saccharomyces cerevisiae CWH8 gene is required for full levels of dolichol-linked oligosaccharides in the endoplasmic reticulum and for efficient N-glycosylation.

Q15532	SSXT_HUMAN	Protein SSXT	15919756	Synovial sarcoma translocation (SYT) encodes a nuclear receptor coactivator.

P54115	ALDH6_YEAST	Magnesium-activated aldehyde dehydrogenase, cytosolic	9473035	Molecular cloning, characterization, and potential roles of cytosolic and mitochondrial aldehyde dehydrogenases in ethanol metabolism in Saccharomyces cerevisiae.

Q5ZC82	LOG_ORYSJ	Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG	17287810	Direct control of shoot meristem activity by a cytokinin-activating enzyme.

Q9UPQ8	DOLK_HUMAN	Dolichol kinase	16923818	Human dolichol kinase, a polytopic endoplasmic reticulum membrane protein with a cytoplasmically oriented CTP-binding site.

Q9P7V2	ABC4_SCHPO	ATP-binding cassette transporter abc4	16849797	A survey of all 11 ABC transporters in fission yeast: two novel ABC transporters are required for red pigment accumulation in a Schizosaccharomyces pombe adenine biosynthetic mutant.

O88618	FTCD_RAT	Formimidoyltransferase-cyclodeaminase	9837973	Molecular cloning, characterization, and dynamics of rat formiminotransferase cyclodeaminase, a Golgi-associated 58-kDa protein.

Q9EPH8	PABP1_RAT	Polyadenylate-binding protein 1	11416190	Vasopressin mRNA localization in nerve cells: characterization of cis-acting elements and trans-acting factors.

Q13148	TADBP_HUMAN	TAR DNA-binding protein 43	11285240	Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping.

P05755	RS9B_YEAST	40S ribosomal protein S9-B	6814480	Isolation of seventeen proteins and amino-terminal amino acid sequences of eight proteins from cytoplasmic ribosomes of yeast.

Q9UBH6	XPR1_HUMAN	Xenotropic and polytropic retrovirus receptor 1	9990033	A human cell-surface receptor for xenotropic and polytropic murine leukemia viruses: possible role in G protein-coupled signal transduction.

Q8IUD6	RN135_HUMAN	E3 ubiquitin-protein ligase RNF135	19484123	REUL is a novel E3 ubiquitin ligase and stimulator of retinoic-acid- inducible gene-I.

P60720	LIPB_ECOLI	Octanoyltransferase	8444795	Lipoic acid metabolism in Escherichia coli: sequencing and functional characterization of the lipA and lipB genes.

P58960	GR39B_DROME	Putative gustatory receptor 39b	10710312	Candidate taste receptors in Drosophila.

Q13470	TNK1_HUMAN	Non-receptor tyrosine-protein kinase TNK1	10873601	Characterization of the tyrosine kinase Tnk1 and its binding with phospholipase C-gamma1.

P45984	MK09_HUMAN	Mitogen-activated protein kinase 9	8654373	Selective interaction of JNK protein kinase isoforms with transcription factors.

Q15389	ANGP1_HUMAN	Angiopoietin-1	8980223	Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning.

Q8K2C9	HACD3_MOUSE	3-hydroxyacyl-CoA dehydratase 3	10747961	B-ind1, a novel mediator of Rac1 signaling cloned from sodium butyrate-treated fibroblasts.

P11348	DHPR_RAT	Dihydropteridine reductase	1898002	Role of aspartate-37 in determining cofactor specificity and binding in rat liver dihydropteridine reductase.

O35495	CDK14_MOUSE	Cell division protein kinase 14	9202329	A novel cdc2-related protein kinase expressed in the nervous system.

O15118	NPC1_HUMAN	Niemann-Pick C1 protein	9211849	Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis.

Q99661	KIF2C_HUMAN	Kinesin-like protein KIF2C	9434124	Cloning and expression of human mitotic centromere-associated kinesin gene.

Q13554	KCC2B_HUMAN	Calcium/calmodulin-dependent protein kinase type II subunit beta	9060999	Identification of novel human tumor cell-specific CaMK-II variants.

P05523	FPG_ECOLI	Formamidopyrimidine-DNA glycosylase	8473347	Fpg protein of Escherichia coli is a zinc finger protein whose cysteine residues have a structural and/or functional role.

Q8RXD6	BRE1A_ARATH	E3 ubiquitin-protein ligase BRE1-like 1	19286969	HISTONE MONOUBIQUITINATION1 interacts with a subunit of the mediator complex and regulates defense against necrotrophic fungal pathogens in Arabidopsis.

Q09161	NCBP1_HUMAN	Nuclear cap-binding protein subunit 1	7937105	Cloning of a complementary DNA encoding an 80 kilodalton nuclear cap binding protein.

Q02283	HAT5_ARATH	Homeobox-leucine zipper protein HAT5	8535134	Ectopic expression of the Arabidopsis transcriptional activator Athb- 1 alters leaf cell fate in tobacco.

Q9XWJ1	SMG9_CAEEL	Protein smg-9	19417104	SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay.

Q13402	MYO7A_HUMAN	Myosin-VIIa	8842737	Human Usher 1B/mouse shaker-1: the retinal phenotype discrepancy explained by the presence/absence of myosin VIIA in the photoreceptor cells.

P46674	SAC3_YEAST	Nuclear mRNA export protein SAC3	15311284	Yeast centrin Cdc31 is linked to the nuclear mRNA export machinery.

Q96291	BAS1A_ARATH	2-Cys peroxiredoxin BAS1, chloroplastic	12084836	The plastidic 2-cysteine peroxiredoxin is a target for a thioredoxin involved in the protection of the photosynthetic apparatus against oxidative damage.

P53634	CATC_HUMAN	Dipeptidyl peptidase 1	7665576	Oligomeric structure and substrate induced inhibition of human cathepsin C.

P38149	DUG2_YEAST	Probable di- and tripeptidase DUG2	17179087	The alternative pathway of glutathione degradation is mediated by a novel protein complex involving three new genes in Saccharomyces cerevisiae.

Q8L910	GPX4_ARATH	Probable glutathione peroxidase 4	14617062	Glutathione peroxidase genes in Arabidopsis are ubiquitous and regulated by abiotic stresses through diverse signaling pathways.

Q92994	TF3B_HUMAN	Transcription factor IIIB 90 kDa subunit	8943358	RNA polymerase III transcription from the human U6 and adenovirus type 2 VAI promoters has different requirements for human BRF, a subunit of human TFIIIB.

Q14562	DHX8_HUMAN	ATP-dependent RNA helicase DHX8	7935475	Identification of a putative RNA helicase (HRH1), a human homolog of yeast Prp22.

P81715	LIE1_STREX	Leupeptin-inactivating enzyme 1	9531495	Characterization of the leupeptin-inactivating enzyme from Streptomyces exfoliatus SMF13 which produces leupeptin.

Q12390	GST2_YEAST	Glutathione S-transferase 2	9792709	A novel membrane-bound glutathione S-transferase functions in the stationary phase of the yeast Saccharomyces cerevisiae.

O00764	PDXK_HUMAN	Pyridoxal kinase	9099727	Human pyridoxal kinase. cDNA cloning, expression, and modulation by ligands of the benzodiazepine receptor.

P34234	LOT5_YEAST	Protein LOT5	14562095	Global analysis of protein localization in budding yeast.

P25303	SCJ1_YEAST	DnaJ-related protein SCJ1	9817751	A role for the DnaJ homologue Scj1p in protein folding in the yeast endoplasmic reticulum.

O81796	IDH3_ARATH	Isocitrate dehydrogenase [NAD] regulatory subunit 3, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

O94657	XDJ1_SCHPO	DnaJ protein homolog xdj1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P23457	DIDH_RAT	3-alpha-hydroxysteroid dehydrogenase	1922097	Molecular cloning and expression of rat liver 3 alpha-hydroxysteroid dehydrogenase.

Q9Z2B5	E2AK3_MOUSE	Eukaryotic translation initiation factor 2-alpha kinase 3	9930704	Protein translation and folding are coupled by an endoplasmic- reticulum-resident kinase.

Q8VHZ8	DSCAM_RAT	Down syndrome cell adhesion molecule homolog	18585357	DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1.

Q0WPT7	Y2104_ARATH	Uncharacterized methyltransferase At2g41040, chloroplastic	16414959	Tocopherol cyclase (VTE1) localization and vitamin E accumulation in chloroplast plastoglobule lipoprotein particles.

Q13627	DYR1A_HUMAN	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	14593110	Phosphorylation of Ser640 in muscle glycogen synthase by DYRK family protein kinases.

P24752	THIL_HUMAN	Acetyl-CoA acetyltransferase, mitochondrial	17371050	Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase: the importance of potassium and chloride ions for its structure and function.

P21156	CYSD_ECOLI	Sulfate adenylyltransferase subunit 2	2828368	The sulfate activation locus of Escherichia coli K12: cloning, genetic, and enzymatic characterization.

Q95203	CAH11_SHEEP	Carbonic anhydrase-related protein 11	9878252	Evolutionarily conserved, 'acatalytic' carbonic anhydrase-related protein XI contains a sequence motif present in the neuropeptide sauvagine: the human CA-RP XI gene (CA11) is embedded between the secretor gene cluster and the DBP gene at 19q13.3.

Q12142	ATG9_YEAST	Autophagy-related protein 9	8224160	Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae.

O60894	RAMP1_HUMAN	Receptor activity-modifying protein 1	9620797	RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor.

Q8N474	SFRP1_HUMAN	Secreted frizzled-related protein 1	10347172	Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signaling.

P17213	BPI_HUMAN	Bactericidal permeability-increasing protein	2722846	Cloning of the cDNA of a human neutrophil bactericidal protein. Structural and functional correlations.

Q96DZ1	ERLEC_HUMAN	Endoplasmic reticulum lectin 1	16531414	The MRH protein Erlectin is a member of the endoplasmic reticulum synexpression group and functions in N-glycan recognition.

P38418	LOX2_ARATH	Lipoxygenase 2, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

O60318	MCM3A_HUMAN	80 kDa MCM3-associated protein	9712829	Identification of a novel MCM3-associated protein that facilitates MCM3 nuclear localization.

P30301	MIP_HUMAN	Lens fiber major intrinsic protein	1840563	Genomic cloning, complete nucleotide sequence, and structure of the human gene encoding the major intrinsic protein (MIP) of the lens.

Q8GXH3	OSB2_ARATH	Protein OSB2, chloroplastic	16326926	pTAC2, -6, and -12 are components of the transcriptionally active plastid chromosome that are required for plastid gene expression.

Q9NZI8	IF2B1_HUMAN	Insulin-like growth factor 2 mRNA-binding protein 1	20080952	ZBP1 recognition of beta-actin zipcode induces RNA looping.

P49410	EFTU_BOVIN	Elongation factor Tu, mitochondrial	15557323	Crystal structure of the bovine mitochondrial elongation factor Tu.Ts complex.

P33314	BUD2_YEAST	Inhibitory regulator protein BUD2/CLA2	8371782	BUD2 encodes a GTPase-activating protein for Bud1/Rsr1 necessary for proper bud-site selection in yeast.

P25105	PTAFR_HUMAN	Platelet-activating factor receptor	1322356	The human platelet-activating factor receptor gene (PTAFR) contains no introns and maps to chromosome 1.

P04762	CATA_RAT	Catalase	2792765	Isolation and characterization of the rat catalase-encoding gene.

Q96QZ7	MAGI1_HUMAN	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1	9647739	Cloning and characterization of BAI-associated protein 1: a PDZ domain-containing protein that interacts with BAI1.

Q04323	UBXN1_HUMAN	UBX domain-containing protein 1	15362974	A novel UBA and UBX domain protein that binds polyubiquitin and VCP and is a substrate for SAPKs.

O76082	S22A5_HUMAN	Solute carrier family 22 member 5	9685390	Molecular and functional identification of sodium ion-dependent, high affinity human carnitine transporter OCTN2.

Q12387	NAA25_YEAST	N-terminal acetyltransferase B complex subunit MDM20	9105043	The yeast gene, MDM20, is necessary for mitochondrial inheritance and organization of the actin cytoskeleton.

Q16401	PSMD5_HUMAN	26S proteasome non-ATPase regulatory subunit 5	19412159	Chaperone-mediated pathway of proteasome regulatory particle assembly.

O70161	PI51C_MOUSE	Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma	14741049	A novel neuronal-specific splice variant of Type I phosphatidylinositol 4-phosphate 5-kinase isoform gamma.

Q05027	TAF9_YEAST	Transcription initiation factor TFIID subunit 9	12138208	Molecular characterization of Saccharomyces cerevisiae TFIID.

Q07066	PXMP2_RAT	Peroxisomal membrane protein 2	8422909	Membrane topology of the 22 kDa integral peroxisomal membrane protein.

Q9LU77	PIN2_ARATH	Auxin efflux carrier component 2	9679062	EIR1, a root-specific protein involved in auxin transport, is required for gravitropism in Arabidopsis thaliana.

Q13627	DYR1A_HUMAN	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	8975710	Isolation of human and murine homologues of the Drosophila minibrain gene: human homologue maps to 21q22.2 in the Down syndrome 'critical region'.

Q8BXK9	CLIC5_MOUSE	Chloride intracellular channel protein 5	17021174	The chloride intracellular channel protein CLIC5 is expressed at high levels in hair cell stereocilia and is essential for normal inner ear function.

Q8K3Y3	LN28A_MOUSE	Protein lin-28 homolog A	12798299	Conservation of the heterochronic regulator Lin-28, its developmental expression and microRNA complementary sites.

P02724	GLPA_HUMAN	Glycophorin-A	3456608	Isolation and characterization of human glycophorin A cDNA clones by a synthetic oligonucleotide approach: nucleotide sequence and mRNA structure.

P70399	TP53B_MOUSE	Tumor suppressor p53-binding protein 1	8910340	p202, an interferon-inducible modulator of transcription, inhibits transcriptional activation by the p53 tumor suppressor protein, and a segment from the p53-binding protein 1 that binds to p202 overcomes this inhibition.

P52895	AK1C2_HUMAN	Aldo-keto reductase family 1 member C2	8573067	Relationship of human liver dihydrodiol dehydrogenases to hepatic bile-acid-binding protein and an oxidoreductase of human colon cells.

P23443	KS6B1_HUMAN	Ribosomal protein S6 kinase beta-1	14673156	mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E.

Q9V7U0	RESIL_DROME	Pro-resilin	11483432	Tentative identification of a resilin gene in Drosophila melanogaster.

Q9UQB8	BAIP2_HUMAN	Brain-specific angiogenesis inhibitor 1-associated protein 2	15289329	IRSp53/Eps8 complex is important for positive regulation of Rac and cancer cell motility/invasiveness.

Q8WWH4	ASZ1_HUMAN	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1	12040005	Identification of Gasz, an evolutionarily conserved gene expressed exclusively in germ cells and encoding a protein with four ankyrin repeats, a sterile-alpha motif, and a basic leucine zipper.

Q9UBK7	RBL2A_HUMAN	Rab-like protein 2A	10444334	Two novel human RAB genes with near identical sequence each map to a telomere-associated region: the subtelomeric region of 22q13.3 and the ancestral telomere band 2q13.

P53192	GET1_YEAST	Golgi to ER traffic protein 1	14562095	Global analysis of protein localization in budding yeast.

Q84Q77	HS17A_ORYSJ	17.9 kDa class I heat shock protein	15803416	Characterization of the genomic structures and selective expression profiles of nine class I small heat shock protein genes clustered on two chromosomes in rice (Oryza sativa L.).

Q27268	UAP56_DROME	ATP-dependent RNA helicase WM6	11696332	The DExH/D box protein HEL/UAP56 is essential for mRNA nuclear export in Drosophila.

Q86A17	DHPR_DICDI	Dihydropteridine reductase	18997329	Crystallization and preliminary characterization of dihydropteridine reductase from Dictyostelium discoideum.

Q9MA41	CTL1_ARATH	Chitinase-like protein 1	7743935	Conditional root expansion mutants of Arabidopsis.

P25578	PGPS1_YEAST	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	9545322	The PEL1 gene (renamed PGS1) encodes the phosphatidylglycero- phosphate synthase of Saccharomyces cerevisiae.

Q91ZW1	TFAM_RAT	Transcription factor A, mitochondrial	12198131	Mitochondrial transcription factor A and its downstream targets are up-regulated in a rat hepatoma.

P41935	HM10_CAEEL	Homeobox protein ceh-10	7789259	The C. elegans neuronally expressed homeobox gene ceh-10 is closely related to genes expressed in the vertebrate eye.

Q2V0W1	PPD_RAPSA	Pheophorbidase	16384908	Characterization and cloning of the chlorophyll-degrading enzyme pheophorbidase from cotyledons of radish.

P46940	IQGA1_HUMAN	Ras GTPase-activating-like protein IQGAP1	8051149	Identification of a human rasGAP-related protein containing calmodulin-binding motifs.

Q9FLP6	SUMO2_ARATH	Small ubiquitin-related modifier 2	17644626	Genetic analysis of SUMOylation in Arabidopsis: conjugation of SUMO1 and SUMO2 to nuclear proteins is essential.

O14519	CDKA1_HUMAN	Cyclin-dependent kinase 2-associated protein 1	9506968	Cloning, mapping, expression, function, and mutation analyses of the human ortholog of the hamster putative tumor suppressor gene Doc-1.

P10586	PTPRF_HUMAN	Receptor-type tyrosine-protein phosphatase F	2972792	A new member of the immunoglobulin superfamily that has a cytoplasmic region homologous to the leukocyte common antigen.

Q9Y5F1	PCDBC_HUMAN	Protocadherin beta-12	10380929	A striking organization of a large family of human neural cadherin- like cell adhesion genes.

P25641	ATG15_YEAST	Putative lipase ATG15	11566994	Aut5/Cvt17p, a putative lipase essential for disintegration of autophagic bodies inside the vacuole.

Q08490	SGO1_YEAST	Shugoshin	14562095	Global analysis of protein localization in budding yeast.

P01848	TCA_HUMAN	T-cell receptor alpha chain C region	12429093	The 1.5 A crystal structure of a highly selected antiviral T cell receptor provides evidence for a structural basis of immunodominance.

Q10357	CCS1_SCHPO	Superoxide dismutase 1 copper chaperone	15107426	The Schizosaccharomyces pombe Pccs protein functions in both copper trafficking and metal detoxification pathways.

P83525	FER_SCOJA	Ferredoxin	12392097	Amino acid sequences of ferredoxins from Scopolia japonica and Lycium chinense: their similarities to that of Datura arborea.

Q9USL7	RSM18_SCHPO	37S ribosomal protein rsm18, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q86XP3	DDX42_HUMAN	ATP-dependent RNA helicase DDX42	19377511	The DEAD box protein Ddx42p modulates the function of ASPP2, a stimulator of apoptosis.

Q03562	BRE3_CAEEL	Beta-1,4-mannosyltransferase bre-3	10924467	Bacillus thuringiensis (Bt) toxin susceptibility and isolation of resistance mutants in the nematode Caenorhabditis elegans.

P01816	HV203_HUMAN	Ig heavy chain V-II region DAW	5449120	The amino acid sequences of the Fd fragments of two human gamma-1 heavy chains.

P04843	RPN1_HUMAN	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1	15835887	Proteomic analysis of mammalian oligosaccharyltransferase reveals multiple subcomplexes that contain Sec61, TRAP, and two potential new subunits.

Q00722	PLCB2_HUMAN	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2	1644792	Cloning, sequencing, expression, and Gq-independent activation of phospholipase C-beta 2.

Q8K299	SCAR5_MOUSE	Scavenger receptor class A member 5	19154717	Scara5 is a ferritin receptor mediating non-transferrin iron delivery.

Q06629	HDA2_YEAST	HDA1 complex subunit 2	11287668	HDA2 and HDA3 are related proteins that interact with and are essential for the activity of the yeast histone deacetylase HDA1.

Q15797	SMAD1_HUMAN	Mothers against decapentaplegic homolog 1	9759503	TGF-beta signal transduction.

P19969	GBRA5_RAT	Gamma-aminobutyric acid receptor subunit alpha-5	2153588	Functional expression and sites of gene transcription of a novel alpha subunit of the GABAA receptor in rat brain.

O42709	MCM10_SCHPO	DNA replication licensing factor mcm10	17112379	The CENP-B homolog, Abp1, interacts with the initiation protein Cdc23 (MCM10) and is required for efficient DNA replication in fission yeast.

P42566	EPS15_HUMAN	Epidermal growth factor receptor substrate 15	8183552	The human eps15 gene, encoding a tyrosine kinase substrate, is conserved in evolution and maps to 1p31-p32.

Q92630	DYRK2_HUMAN	Dual specificity tyrosine-phosphorylation-regulated kinase 2	11311121	The kinase DYRK phosphorylates protein-synthesis initiation factor eIF2Bepsilon at Ser539 and the microtubule-associated protein tau at Thr212: potential role for DYRK as a glycogen synthase kinase 3- priming kinase.

Q9H5J8	TAF1D_HUMAN	TATA box-binding protein-associated factor RNA polymerase I subunit D	15520167	A novel nuclear protein, MGC5306 interacts with DNA polymerase beta and has a potential role in cellular phenotype.

Q8TAM2	TTC8_HUMAN	Tetratricopeptide repeat protein 8	17574030	A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis.

Q9M4B5	PFD4_ARATH	Probable prefoldin subunit 4	10743655	Interactions of the developmental regulator ABI3 with proteins identified from developing Arabidopsis seeds.

Q9Y618	NCOR2_HUMAN	Nuclear receptor corepressor 2	10809664	A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40- repeat protein linked to deafness.

O81223	CNBL4_ARATH	Calcineurin B-like protein 4	10725350	The Arabidopsis SOS2 protein kinase physically interacts with and is activated by the calcium-binding protein SOS3.

P60572	PANX3_RAT	Pannexin-3	14597722	Pannexins, a family of gap junction proteins expressed in brain.

Q9NZJ0	DTL_HUMAN	Denticleless protein homolog	17085480	DTL/CDT2 is essential for both CDT1 regulation and the early G2/M checkpoint.

P39305	ULAE_ECOLI	L-ribulose-5-phosphate 3-epimerase ulaE	14996803	Regulation of expression of the divergent ulaG and ulaABCDEF operons involved in L-ascorbate dissimilation in Escherichia coli.

Q9SAF1	ARP3_ARATH	Actin-related protein 3	12906796	Requirements for Arabidopsis ATARP2 and ATARP3 during epidermal development.

Q9WV76	AP4B1_MOUSE	AP-4 complex subunit beta-1	10436028	Characterization of a fourth adaptor-related protein complex.

P02920	LACY_ECOLI	Lactose permease	12893935	Structure and mechanism of the lactose permease of Escherichia coli.

Q9LFV6	RPOT2_ARATH	DNA-directed RNA polymerase 2, chloroplastic/mitochondrial	18567673	Intraplastidial trafficking of a phage-type RNA polymerase is mediated by a thylakoid RING-H2 protein.

Q9JK00	SCN3B_RAT	Sodium channel subunit beta-3	10688874	Beta3: an additional auxiliary subunit of the voltage-sensitive sodium channel that modulates channel gating with distinct kinetics.

P07263	SYH_YEAST	Histidyl-tRNA synthetase, mitochondrial	3521891	The HTS1 gene encodes both the cytoplasmic and mitochondrial histidine tRNA synthetases of S. cerevisiae.

P69850	DAD3_YEAST	DASH complex subunit DAD3	15640796	The yeast DASH complex forms closed rings on microtubules.

P01601	KV109_HUMAN	Ig kappa chain V-I region HK101	6779204	Human immunoglobulin variable region genes -- DNA sequences of two V kappa genes and a pseudogene.

Q9D309	FAM3B_MOUSE	Protein FAM3B	12160727	Cloning, expression, and initial characterization of a novel cytokine-like gene family.

Q16674	MIA_HUMAN	Melanoma-derived growth regulatory protein	7923218	Cloning of a novel malignant melanoma-derived growth-regulatory protein, MIA.

Q4W815	EPOR_XENLA	Erythropoietin receptor	16378761	Cloning and expression pattern of the Xenopus erythropoietin receptor.

Q8VHD6	GTR10_MOUSE	Solute carrier family 2, facilitated glucose transporter member 10	11592815	Sequence and functional analysis of GLUT10: a glucose transporter in the Type 2 diabetes-linked region of chromosome 20q12-13.1.

O76011	KRT34_HUMAN	Keratin, type I cuticular Ha4	9756910	Characterization of a 190-kilobase pair domain of human type I hair keratin genes.

P0C152	MKS3_RAT	Meckelin	19815549	Meckel-Gruber syndrome protein MKS3 is required for endoplasmic reticulum-associated degradation of surfactant protein C.

O82171	AGD10_ARATH	ADP-ribosylation factor GTPase-activating protein AGD10	15634699	Genetic and molecular identification of genes required for female gametophyte development and function in Arabidopsis.

Q08AM6	VAC14_HUMAN	Protein VAC14 homolog	17556371	Core protein machinery for mammalian phosphatidylinositol 3,5- bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complex.

Q9LVI8	GLN13_ARATH	Glutamine synthetase cytosolic isozyme 1-3	16338958	Gln49 and Ser174 residues play critical roles in determining the catalytic efficiencies of plant glutamine synthetase.

B7ZR65	SOX9A_XENLA	Transcription factor Sox-9-A	16256735	SoxE factors function equivalently during neural crest and inner ear development and their activity is regulated by SUMOylation.

O15260	SURF4_HUMAN	Surfeit locus protein 4	15308636	Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46.

Q9UK80	UBP21_HUMAN	Ubiquitin carboxyl-terminal hydrolase 21	10799498	Identification of a novel isopeptidase with dual specificity for ubiquitin- and NEDD8-conjugated proteins.

Q12117	MRH1_YEAST	Protein MRH1	12469340	Subproteomics: identification of plasma membrane proteins from the yeast Saccharomyces cerevisiae.

O94623	REV1_SCHPO	DNA repair protein rev1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8VED2	CNO_MOUSE	Protein cappuccino	11110696	Defects in the cappuccino (cno) gene on mouse chromosome 5 and human 4p cause Hermansky-Pudlak syndrome by an AP-3-independent mechanism.

Q6PGB6	NAA50_MOUSE	N-alpha-acetyltransferase 50, NatE catalytic subunit	16484612	Embryonic growth-associated protein is one subunit of a novel N- terminal acetyltransferase complex essential for embryonic vascular development.

P30043	BLVRB_HUMAN	Flavin reductase	11224564	Structure of human biliverdin IXbeta reductase, an early fetal bilirubin IXbeta producing enzyme.

P15280	GLGS_ORYSJ	Glucose-1-phosphate adenylyltransferase small subunit, chloroplastic/amyloplastic	1847888	Molecular characterization of the gene encoding a rice endosperm- specific ADPglucose pyrophosphorylase subunit and its developmental pattern of transcription.

Q9VFP2	RDX_DROME	Protein roadkill	16651542	Roadkill attenuates Hedgehog responses through degradation of Cubitus interruptus.

O74534	SLY1_SCHPO	Protein sly1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9MA17	SMB_ARATH	Protein SOMBRERO	20197506	SOMBRERO, BEARSKIN1, and BEARSKIN2 regulate root cap maturation in Arabidopsis.

P33886	WIS1_SCHPO	Protein kinase wis1	1756736	The wis1 protein kinase is a dosage-dependent regulator of mitosis in Schizosaccharomyces pombe.

Q5XG87	PAPD7_HUMAN	DNA polymerase sigma	10066793	The topoisomerase-related function gene TRF4 affects cellular sensitivity to the antitumor agent camptothecin.

P26442	AMFR1_HUMAN	Autocrine motility factor receptor, isoform 1	1649192	Purification of human tumor cell autocrine motility factor and molecular cloning of its receptor.

Q8WZJ9	HUT1_SCHPO	UDP-galactose transporter homolog 1	11284010	Hut1 proteins identified in Saccharomyces cerevisiae and Schizosaccharomyces pombe are functional homologues involved in the protein-folding process at the endoplasmic reticulum.

P54136	SYRC_HUMAN	Arginyl-tRNA synthetase, cytoplasmic	7590355	Cloning and characterization of cDNA encoding a human arginyl-tRNA synthetase.

Q9HC62	SENP2_HUMAN	Sentrin-specific protease 2	12192048	Enzymes of the SUMO modification pathway localize to filaments of the nuclear pore complex.

Q9XYP7	GCP2_DROME	Gamma-tubulin complex component 2 homolog	10037793	Characterization of two related Drosophila gamma-tubulin complexes that differ in their ability to nucleate microtubules.

P07306	ASGR1_HUMAN	Asialoglycoprotein receptor 1	11543633	Cloning, mapping, and characterization of a human homologue of the yeast longevity assurance gene LAG1.

P92934	AAP6_ARATH	Amino acid permease 6	12148530	Low and high affinity amino acid H+-cotransporters for cellular import of neutral and charged amino acids.

O15392	BIRC5_HUMAN	Baculoviral IAP repeat-containing protein 5	10876248	Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement.

P18859	ATP5J_HUMAN	ATP synthase-coupling factor 6, mitochondrial	1830479	Molecular cloning of cDNA for the import precursor of human coupling factor 6 of H(+)-ATP synthase in mitochondria.

P80668	FEAB_ECOLI	Phenylacetaldehyde dehydrogenase	9043126	2-phenylethylamine catabolism by Escherichia coli K-12: gene organization and expression.

P05106	ITB3_HUMAN	Integrin beta-3	1438206	Ser-752-->Pro mutation in the cytoplasmic domain of integrin beta 3 subunit and defective activation of platelet integrin alpha IIb beta 3 (glycoprotein IIb-IIIa) in a variant of Glanzmann thrombasthenia.

Q810H6	DISC1_RAT	Disrupted in schizophrenia 1 homolog	12506198	Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth.

P06576	ATPB_HUMAN	ATP synthase subunit beta, mitochondrial	2870059	Human F1-ATPase: molecular cloning of cDNA for the beta subunit.

Q8MR31	SLIP1_DROME	Slo-interacting protein 1	9502797	dSLo interacting protein 1, a novel protein that interacts with large-conductance calcium-activated potassium channels.

P50151	GBG10_HUMAN	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10	7665596	Isolation of cDNA clones encoding eight different human G protein gamma subunits, including three novel forms designated the gamma 4, gamma 10, and gamma 11 subunits.

Q9FWR4	DHAR1_ARATH	Glutathione S-transferase DHAR1, mitochondrial	12077129	Functional divergence in the glutathione transferase superfamily in plants. Identification of two classes with putative functions in redox homeostasis in Arabidopsis thaliana.

P25378	RHEB_YEAST	Rheb-like protein RHB1	12456008	Interaction with Btn2p is required for localization of Rsglp: Btn2p- mediated changes in arginine uptake in Saccharomyces cerevisiae.

P16520	GBB3_HUMAN	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3	2107550	Molecular cloning of beta 3 subunit, a third form of the G protein beta-subunit polypeptide.

P52485	UBCD2_DROME	Ubiquitin-conjugating enzyme E2-24 kDa	8576256	Identification of a novel family of ubiquitin-conjugating enzymes with distinct amino-terminal extensions.

O14933	UB2L6_HUMAN	Ubiquitin/ISG15-conjugating enzyme E2 L6	9153201	Physical interaction between specific E2 and Hect E3 enzymes determines functional cooperativity.

P41227	NAA10_HUMAN	N-alpha-acetyltransferase 10, NatA catalytic subunit	16507339	Cloning and characterization of hNAT5/hSAN: an evolutionarily conserved component of the NatA protein N-alpha-acetyltransferase complex.

Q64573	EST4_RAT	Liver carboxylesterase 4	8611161	Cloning and sequencing of rat liver carboxylesterase ES-4 (microsomal palmitoyl-CoA hydrolase).

Q4VC33	MAEA_MOUSE	Macrophage erythroblast attacher	16707498	Absence of erythroblast macrophage protein (Emp) leads to failure of erythroblast nuclear extrusion.

O14170	POP2_SCHPO	WD repeat-containing protein pop2	14970237	Requirement of the SCFPop1/Pop2 ubiquitin ligase for degradation of the fission yeast S phase cyclin Cig2.

P26801	CEBPG_RAT	CCAAT/enhancer-binding protein gamma	1377818	Molecular cloning of two C/EBP-related proteins that bind to the promoter and the enhancer of the alpha 1-fetoprotein gene. Further analysis of C/EBP beta and C/EBP gamma.

Q39090	UFO_ARATH	Protein UNUSUAL FLORAL ORGANS	10607296	The UNUSUAL FLORAL ORGANS gene of Arabidopsis thaliana is an F-box protein required for normal patterning and growth in the floral meristem.

Q9M7Q3	AI5L6_ARATH	ABSCISIC ACID-INSENSITIVE 5-like protein 6	11884679	Arabidopsis basic leucine zipper proteins that mediate stress- responsive abscisic acid signaling.

P38858	SOL3_YEAST	6-phosphogluconolactonase 3	14562095	Global analysis of protein localization in budding yeast.

Q9EP93	V1R53_MOUSE	Vomeronasal type-1 receptor 53	11116090	Sequence diversity and genomic organization of vomeronasal receptor genes in the mouse.

Q02948	VPS30_YEAST	Vacuolar protein sorting-associated protein 30	9105038	Endosome to Golgi retrieval of the vacuolar protein sorting receptor, Vps10p, requires the function of the VPS29, VPS30, and VPS35 gene products.

P32351	IMPX_YEAST	Sugar utilization regulatory protein IMP2	1561839	IMP2, a nuclear gene controlling the mitochondrial dependence of galactose, maltose and raffinose utilization in Saccharomyces cerevisiae.

P22148	MSN1_YEAST	Protein MSN1	2263457	Increased dosage of the MSN1 gene restores invertase expression in yeast mutants defective in the SNF1 protein kinase.

Q02771	PT117_YEAST	Protein PET117, mitochondrial	8381337	Sequence and chromosomal localization of two PET genes required for cytochrome c oxidase assembly in Saccharomyces cerevisiae.

P53238	PEF1_YEAST	Peflin	17640275	The yeast penta-EF protein Pef1p is involved in cation-dependent budding and cell polarization.

Q95V25	SLO1_CAEEL	Calcium-activated potassium channel slo-1	14675531	A central role of the BK potassium channel in behavioral responses to ethanol in C. elegans.

Q9XZ58	CSN5_DROME	COP9 signalosome complex subunit 5	12397113	CSN5/Jab1 mutations affect axis formation in the Drosophila oocyte by activating a meiotic checkpoint.

P06104	UBC2_YEAST	Ubiquitin-conjugating enzyme E2 2	1651502	The N-end rule is mediated by the UBC2(RAD6) ubiquitin-conjugating enzyme.

P36589	CDC14_SCHPO	Cell division control protein 14	10775265	The role of the sid1p kinase and cdc14p in regulating the onset of cytokinesis in fission yeast.

Q99542	MMP19_HUMAN	Matrix metalloproteinase-19	9020145	Identification and characterization of a novel human matrix metalloproteinase with unique structural characteristics, chromosomal location and tissue distribution.

O14522	PTPRT_HUMAN	Receptor-type tyrosine-protein phosphatase T	9602027	Identification and characterization of RPTP rho, a novel RPTP mu/kappa-like receptor protein tyrosine phosphatase whose expression is restricted to the central nervous system.

P36164	TVP38_YEAST	Golgi apparatus membrane protein TVP38	14562095	Global analysis of protein localization in budding yeast.

P51142	DVL2_XENLA	Segment polarity protein dishevelled homolog DVL-2	10698942	Dishevelled phosphorylation, subcellular localization and multimerization regulate its role in early embryogenesis.

Q9US47	SSDH1_SCHPO	Putative succinate-semialdehyde dehydrogenase C1002.12c [NADP+]	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q62036	AZI1_MOUSE	5-azacytidine-induced protein 1	9070930	Genomic organization of the mouse AZ1 gene that encodes the protein localized to preacrosomes of spermatids.

P52893	ALAM_YEAST	Probable alanine aminotransferase, mitochondrial	11502169	Yeast mitochondrial dehydrogenases are associated in a supramolecular complex.

O13852	POZ1_SCHPO	Protection of telomeres protein poz1	18535244	Fission yeast Pot1-Tpp1 protects telomeres and regulates telomere length.

Q9Y5A7	NUB1_HUMAN	NEDD8 ultimate buster 1	16707496	The UBA domains of NUB1L are required for binding but not for accelerated degradation of the ubiquitin-like modifier FAT10.

P48239	GTO1_YEAST	Glutathione S-transferase omega-like 1	16936141	A peroxisomal glutathione transferase of Saccharomyces cerevisiae is functionally related to sulfur amino acid metabolism.

Q5K2P6	K1C11_PROAT	Keratin, type 1 cytoskeletal 11	15819414	Evolution of tissue-specific keratins as deduced from novel cDNA sequences of the lungfish Protopterus aethiopicus.

P12398	HSP77_YEAST	Heat shock protein SSC1, mitochondrial	14517234	Tim14, a novel key component of the import motor of the TIM23 protein translocase of mitochondria.

P54274	TERF1_HUMAN	Telomeric repeat-binding factor 1	15608617	How the human telomeric proteins TRF1 and TRF2 recognize telomeric DNA: a view from high-resolution crystal structures.

O14248	TEA3_SCHPO	Tip elongation aberrant protein 3	12007420	Tea3p is a cell end marker activating polarized growth in Schizosaccharomyces pombe.

P34118	MVPA_DICDI	Major vault protein alpha	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P98161	PKD1_HUMAN	Polycystin-1	7663510	The polycystic kidney disease 1 (PKD1) gene encodes a novel protein with multiple cell recognition domains.

P49683	PRLHR_HUMAN	Prolactin-releasing peptide receptor	9607765	A prolactin-releasing peptide in the brain.

O88370	PI42C_RAT	Phosphatidylinositol-5-phosphate 4-kinase type-2 gamma	9685379	A novel phosphatidylinositol-5-phosphate 4-kinase (phosphatidylinositol-phosphate kinase IIgamma) is phosphorylated in the endoplasmic reticulum in response to mitogenic signals.

Q6DE08	AUKBA_XENLA	Serine/threonine-protein kinase 12-A	12919681	An inner centromere protein that stimulates the microtubule depolymerizing activity of a KinI kinesin.

P25857	G3PB_ARATH	Glyceraldehyde-3-phosphate dehydrogenase B, chloroplastic	12766230	Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.

P09497	CLCB_HUMAN	Clathrin light chain B	15533940	Huntingtin-interacting protein 1 (Hip1) and Hip1-related protein (Hip1R) bind the conserved sequence of clathrin light chains and thereby influence clathrin assembly in vitro and actin distribution in vivo.

P19387	RPB3_HUMAN	DNA-directed RNA polymerase II subunit RPB3	9852112	Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.

Q920A1	CLTR2_MOUSE	Cysteinyl leukotriene receptor 2	11591709	The murine cysteinyl leukotriene 2 (CysLT2) receptor. cDNA and genomic cloning, alternative splicing, and in vitro characterization.

O75792	RNH2A_HUMAN	Ribonuclease H2 subunit A	9789007	Cloning of the cDNA encoding the large subunit of human RNase HI, a homologue of the prokaryotic RNase HII.

Q21773	DHP1_CAEEL	Dihydropyrimidinase 1	11167013	Cloning and characterization of the Caenorhabditis elegans CeCRMP/DHP-1 and -2; common ancestors of CRMP and dihydropyrimidinase?

Q9ULZ3	ASC_HUMAN	Apoptosis-associated speck-like protein containing a CARD	10567338	ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells.

Q9FHW7	SKP1B_ARATH	SKP1-like protein 1B	10607296	The UNUSUAL FLORAL ORGANS gene of Arabidopsis thaliana is an F-box protein required for normal patterning and growth in the floral meristem.

P0A720	KTHY_ECOLI	Thymidylate kinase	8631667	Escherichia coli thymidylate kinase: molecular cloning, nucleotide sequence, and genetic organization of the corresponding tmk locus.

Q92889	XPF_HUMAN	DNA repair endonuclease XPF	19595722	Drosophila MUS312 and the vertebrate ortholog BTBD12 interact with DNA structure-specific endonucleases in DNA repair and recombination.

Q9C1X2	YN53_SCHPO	Putative D-lactate dehydrogenase C713.03, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

A6NDV4	TMM8B_HUMAN	Transmembrane protein 8B	15498789	Role of a novel EGF-like domain-containing gene NGX6 in cell adhesion modulation in nasopharyngeal carcinoma cells.

P35711	SOX5_HUMAN	Transcription factor SOX-5	8812465	Cloning and characterization of SOX5, a new member of the human SOX gene family.

P32849	RAD5_YEAST	DNA repair protein RAD5	16224103	The RING finger ATPase Rad5p of Saccharomyces cerevisiae contributes to DNA double-strand break repair in a ubiquitin-independent manner.

O94921	CDK14_HUMAN	Cell division protein kinase 14	20059949	Cell cycle control of wnt receptor activation.

Q06697	CDC73_YEAST	Cell division control protein 73	12242279	RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach.

P15278	FAS3_DROME	Fasciclin-3	2509076	Fasciclin III: a novel homophilic adhesion molecule in Drosophila.

Q9C103	EME1_SCHPO	Crossover junction endonuclease eme1	14704204	Fission yeast Mus81.Eme1 Holliday junction resolvase is required for meiotic crossing over but not for gene conversion.

Q56UJ5	H6S1A_DANRE	Heparan-sulfate 6-O-sulfotransferase 1-A	16009360	A unique role for 6-O sulfation modification in zebrafish vascular development.

Q12459	PRM7_YEAST	Pheromone-regulated protein PRM7	11062271	Prm1p, a pheromone-regulated multispanning membrane protein, facilitates plasma membrane fusion during yeast mating.

P46527	CDN1B_HUMAN	Cyclin-dependent kinase inhibitor 1B	18593906	Pim kinases promote cell cycle progression by phosphorylating and down-regulating p27Kip1 at the transcriptional and posttranscriptional levels.

P15703	BGL2_YEAST	Glucan 1,3-beta-glucosidase	2509432	Molecular cloning of a cell wall exo-beta-1,3-glucanase from Saccharomyces cerevisiae.

P42838	LEM3_YEAST	Alkylphosphocholine resistance protein LEM3	12133835	A novel membrane protein, Ros3p, is required for phospholipid translocation across the plasma membrane in Saccharomyces cerevisiae.

P50088	SPG1_YEAST	Stationary phase gene 1 protein	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P11679	K2C8_MOUSE	Keratin, type II cytoskeletal 8	2467842	Complete sequence of the mouse type-II keratin EndoA: its amino- terminal region resembles mitochondrial signal peptides.

Q9AT00	AB13I_ARATH	Protein TRIGALACTOSYLDIACYLGLYCEROL 3, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q8VH46	AFAP1_RAT	Actin filament-associated protein 1	12114187	Molecular cloning of actin filament-associated protein: a putative adaptor in stretch-induced Src activation.

Q8MV48	GALT7_DROME	N-acetylgalactosaminyltransferase 7	12829714	Functional characterization and expression analysis of members of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family from Drosophila melanogaster.

O75448	MED24_HUMAN	Mediator of RNA polymerase II transcription subunit 24	10235266	Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex.

Q02818	NUCB1_HUMAN	Nucleobindin-1	1520323	Molecular cloning of nucleobindin, a novel DNA-binding protein that contains both a signal peptide and a leucine zipper structure.

P53257	TPC1_YEAST	Mitochondrial thiamine pyrophosphate carrier 1	12411483	Identification and reconstitution of the yeast mitochondrial transporter for thiamine pyrophosphate.

O01829	SSP19_CAEEL	Sperm-specific class P protein 19	15388931	Structure of sperm-specific protein SSP-19 from Caenorhabditis elegans.

P57088	TMM33_HUMAN	Transmembrane protein 33	17081065	Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.

Q9UHN1	DPOG2_HUMAN	DNA polymerase subunit gamma-2, mitochondrial	10608893	The mitochondrial p55 accessory subunit of human DNA polymerase gamma enhances DNA binding, promotes processive DNA synthesis, and confers N-ethylmaleimide resistance.

Q07343	PDE4B_HUMAN	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	9371714	Molecular cloning and transient expression in COS7 cells of a novel human PDE4B cAMP-specific phosphodiesterase, HSPDE4B3.

P61962	DCAF7_HUMAN	DDB1- and CUL4-associated factor 7	9192870	The an11 locus controlling flower pigmentation in petunia encodes a novel WD-repeat protein conserved in yeast, plants, and animals.

Q08460	KCMA1_MOUSE	Calcium-activated potassium channel subunit alpha-1	7687074	mSlo, a complex mouse gene encoding 'maxi' calcium-activated potassium channels.

O95171	SCEL_HUMAN	Sciellin	9813070	cDNA cloning and characterization of sciellin, a LIM domain protein of the keratinocyte cornified envelope.

Q12032	AIM41_YEAST	Altered inheritance of mitochondria protein 41, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q54WK1	Y9609_DICDI	Putative actin-fragmin kinase DDB_G0279609	15817229	Reverse genetic analyses of gamete-enriched genes revealed a novel regulator of the cAMP signaling pathway in Dictyostelium discoideum.

Q15223	PVRL1_HUMAN	Poliovirus receptor-related protein 1	11544254	Nectin4/PRR4, a new afadin-associated member of the nectin family that trans-interacts with nectin1/PRR1 through V domain interaction.

P84828	SKSP3_ASCTR	Skin secreted peptide 3	15922344	Bradykinin-related peptides and tryptophyllins in the skin secretions of the most primitive extant frog, Ascaphus truei.

O13850	COQ9_SCHPO	Ubiquinone biosynthesis protein coq9, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P38242	ALG14_YEAST	UDP-N-acetylglucosamine transferase subunit ALG14	16100110	Alg14 recruits Alg13 to the cytoplasmic face of the endoplasmic reticulum to form a novel bipartite UDP-N-acetylglucosamine transferase required for the second step of N-linked glycosylation.

P30793	GCH1_HUMAN	GTP cyclohydrolase 1	16778797	GTP cyclohydrolase feedback regulatory protein controls cofactor 6- tetrahydrobiopterin synthesis in the cytosol and in the nucleus of epidermal keratinocytes and melanocytes.

P98177	FOXO4_HUMAN	Forkhead box protein O4	16114898	14-3-3 protein interacts with nuclear localization sequence of forkhead transcription factor FoxO4.

Q9U298	ACH8_CAEEL	Neuronal acetylcholine receptor subunit eat-2	9789046	The genetics of caloric restriction in Caenorhabditis elegans.

P67870	CSK2B_HUMAN	Casein kinase II subunit beta	2666134	Human phosvitin/casein kinase type II. Molecular cloning and sequencing of full-length cDNA encoding subunit beta.

P97799	NRSN1_MOUSE	Neurensin-1	12445626	Developmentally regulated expression of Neuro-p24 and its possible function in neurite extension.

P05067	A4_HUMAN	Amyloid beta A4 protein	8855266	Association of a novel human FE65-like protein with the cytoplasmic domain of the beta-amyloid precursor protein.

Q9UUC9	MDM34_SCHPO	Mitochondrial distribution and morphology protein 34	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UUG6	YFT2_SCHPO	UPF0656 protein C926.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O65155	KELP_ARATH	RNA polymerase II transcriptional coactivator KELP	9681033	Isolation of putative plant transcriptional coactivators using a modified two-hybrid system incorporating a GFP reporter gene.

O15072	ATS3_HUMAN	A disintegrin and metalloproteinase with thrombospondin motifs 3	11408482	Procollagen II amino propeptide processing by ADAMTS-3. Insights on dermatosparaxis.

P98106	LYAM3_RAT	P-selectin	7520013	Cloning, sequence comparison and in vivo expression of the gene encoding rat P-selectin.

Q08817	SOG2_YEAST	Leucine-rich repeat-containing protein SOG2	12972564	RAM: a conserved signaling network that regulates Ace2p transcriptional activity and polarized morphogenesis.

P70054	FEN1B_XENLA	Flap endonuclease 1-B	9852084	Characterization of FEN-1 from Xenopus laevis. cDNA cloning and role in DNA metabolism.

Q08647	PUS7_YEAST	Multisubstrate pseudouridine synthase 7	14561887	The Saccharomyces cerevisiae U2 snRNA:pseudouridine-synthase Pus7p is a novel multisite-multisubstrate RNA:Psi-synthase also acting on tRNAs.

O43776	SYNC_HUMAN	Asparaginyl-tRNA synthetase, cytoplasmic	9421509	Human cytosolic asparaginyl-tRNA synthetase: cDNA sequence, functional expression in Escherichia coli and characterization as human autoantigen.

P53867	ATG4_YEAST	Cysteine protease ATG4	11038174	The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway.

Q06698	YL419_YEAST	Putative ATP-dependent RNA helicase YLR419W	14562095	Global analysis of protein localization in budding yeast.

P40215	NDH1_YEAST	External NADH-ubiquinone oxidoreductase 1, mitochondrial	12032156	Kinetic regulation of the mitochondrial glycerol-3-phosphate dehydrogenase by the external NADH dehydrogenase in Saccharomyces cerevisiae.

P29534	VCAM1_RAT	Vascular cell adhesion protein 1	1377031	Nucleotide sequence of rat vascular cell adhesion molecule-1 cDNA.

Q9EQG5	BEAN_MOUSE	Protein BEAN	11042109	Identification of multiple proteins expressed in murine embryos as binding partners for the WW domains of the ubiquitin-protein ligase Nedd4.

Q9UKB1	FBW1B_HUMAN	F-box/WD repeat-containing protein 11	20347421	Priming and extending: a UbcH5/Cdc34 E2 handoff mechanism for polyubiquitination on a SCF substrate.

Q14565	DMC1_HUMAN	Meiotic recombination protein DMC1/LIM15 homolog	8590282	Expression profiles of a human gene identified as a structural homologue of meiosis-specific recA-like genes.

Q9NS25	SPNXB_HUMAN	Sperm protein associated with the nucleus on the X chromosome B/F	10906052	Spermatid-specific expression of the novel X-linked gene product SPAN-X localized to the nucleus of human spermatozoa.

P23381	SYWC_HUMAN	Tryptophanyl-tRNA synthetase, cytoplasmic	11773626	A human aminoacyl-tRNA synthetase as a regulator of angiogenesis.

Q29980	MICB_HUMAN	MHC class I polypeptide-related sequence B	12569559	Expression and role of MICA and MICB in human hepatocellular carcinomas and their regulation by retinoic acid.

Q16558	KCMB1_HUMAN	Calcium-activated potassium channel subunit beta-1	8612769	A calcium switch for the functional coupling between alpha (hslo) and beta subunits (KV,Ca beta) of maxi K channels.

Q9JMB7	PIWL1_MOUSE	Piwi-like protein 1	11578866	Two mouse piwi-related genes: miwi and mili.

Q12455	SPSY_YEAST	Spermine synthase	9573363	Spermine is not essential for growth of Saccharomyces cerevisiae: identification of the SPE4 gene (spermine synthase) and characterization of a spe4 deletion mutant.

Q92830	KAT2A_HUMAN	Histone acetyltransferase KAT2A	8552087	Identification of human proteins functionally conserved with the yeast putative adaptors ADA2 and GCN5.

P63092	GNAS2_HUMAN	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	9727013	A novel mutation in the switch 3 region of Gs-alpha in a patient with Albright hereditary osteodystrophy impairs GDP binding and receptor activation.

P16278	BGAL_HUMAN	Beta-galactosidase	3143362	Cloning, sequencing, and expression of cDNA for human beta- galactosidase.

Q9NRK6	ABCBA_HUMAN	ATP-binding cassette sub-family B member 10, mitochondrial	10922475	M-ABC2, a new human mitochondrial ATP-binding cassette membrane protein.

Q8LBB7	LOG5_ARATH	Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG5	19837870	Functional analyses of LONELY GUY cytokinin-activating enzymes reveal the importance of the direct activation pathway in Arabidopsis.

O00841	CUDA_DICDI	Putative transcriptional regulator cudA	9226443	CudA: a Dictyostelium gene with pleiotropic effects on cellular differentiation and slug behaviour.

P14242	PMS1_YEAST	DNA mismatch repair protein PMS1	10570173	Functional specificity of MutL homologs in yeast: evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction.

Q05028	PDGFB_RAT	Platelet-derived growth factor subunit B	7758166	A subpopulation of smooth muscle cells in injured rat arteries expresses platelet-derived growth factor-B chain mRNA.

Q9NA13	IPLA_DICDI	Inositol 1,4,5-trisphosphate receptor-like protein A	17077123	Influx of extracellular Ca2+ is necessary for electrotaxis in Dictyostelium.

O00116	ADAS_HUMAN	Alkyldihydroxyacetonephosphate synthase, peroxisomal	9187299	Nucleotide sequence of human alkyl-dihydroxyacetonephosphate synthase cDNA reveals the presence of a peroxisomal targeting signal 2.

Q03435	NHP10_YEAST	Non-histone protein 10	12887900	Involvement of actin-related proteins in ATP-dependent chromatin remodeling.

Q61817	CREB3_MOUSE	Cyclic AMP-responsive element-binding protein 3	8112612	LZIP-1 and LZIP-2: two novel members of the bZIP family.

O35800	HIF1A_RAT	Hypoxia-inducible factor 1-alpha	11237857	Perivenous expression of the mRNA of the three hypoxia-inducible factor a-subunits HIF-1a, HIF2a and HIF3a in rat liver.

Q9UTE4	YFM8_SCHPO	Uncharacterized glutamine amidotransferase C222.08c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P20226	TBP_HUMAN	TATA-box-binding protein	2363050	Functional domains and upstream activation properties of cloned human TATA binding protein.

O60890	OPHN1_HUMAN	Oligophrenin-1	9582072	Oligophrenin-1 encodes a rhoGAP protein involved in X-linked mental retardation.

P05787	K2C8_HUMAN	Keratin, type II cytoskeletal 8	15731013	Identification of trichoplein, a novel keratin filament-binding protein.

P02654	APOC1_HUMAN	Apolipoprotein C-I	2897845	Exact localization of the familial dysbetalipoproteinemia associated HpaI restriction site in the promoter region of the APOC1 gene.

Q9QZD8	DIC_MOUSE	Mitochondrial dicarboxylate carrier	10567211	Predominant expression of the mitochondrial dicarboxylate carrier in white adipose tissue.

Q9V8F5	IM23_DROME	Immune-induced peptide 23	9736738	Differential display of peptides induced during the immune response of Drosophila: a matrix-assisted laser desorption ionization time-of- flight mass spectrometry study.

O15706	VACA_DICDI	Vacuolin-A	16750281	Vacuolin, a flotillin/reggie-related protein from Dictyostelium oligomerizes for endosome association.

A6H687	SAC31_MOUSE	SAC3 domain-containing protein 1	15322101	The Sac3 homologue shd1 is involved in mitotic progression in mammalian cells.

Q9HGN4	MUG20_SCHPO	Meiotically up-regulated gene 20 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9WTX6	CUL1_MOUSE	Cullin-1	10508527	Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E.

Q12311	NTO1_YEAST	NuA3 HAT complex component NTO1	17157260	Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs.

Q15782	CH3L2_HUMAN	Chitinase-3-like protein 2	8702629	Isolation and sequence of a novel human chondrocyte protein related to mammalian members of the chitinase protein family.

P04925	PRIO_MOUSE	Major prion protein	11571277	PrPC directly interacts with proteins involved in signaling pathways.

P38181	NU170_YEAST	Nucleoporin NUP170	11290711	Novel role for a Saccharomyces cerevisiae nucleoporin, Nup170p, in chromosome segregation.

Q6NT76	HMBX1_HUMAN	Homeobox-containing protein 1	19757162	Characterization of a novel human HMBOX1 splicing variant lacking the homeodomain and with attenuated transcription repressor activity.

P06803	PIM1_MOUSE	Proto-oncogene serine/threonine-protein kinase pim-1	1825810	The pim-1 oncogene encodes two related protein-serine/threonine kinases by alternative initiation at AUG and CUG.

P41543	OST1_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1	16297388	Yeast oligosaccharyltransferase consists of two functionally distinct sub-complexes, specified by either the Ost3p or Ost6p subunit.

Q3URR7	ZSC10_MOUSE	Zinc finger and SCAN domain-containing protein 10	17628018	Zfp206 is a transcription factor that controls pluripotency of embryonic stem cells.

P81802	FIBR_EISFO	Fibrinolytic enzyme large subunit	9467874	Purification and characterization of an SDS-activated fibrinolytic enzyme from Eisenia fetida.

Q9SQK3	EM506_ARATH	Ankyrin repeat domain-containing protein EMB506, chloroplastic	17092312	AKRP and EMB506 are two ankyrin repeat proteins essential for plastid differentiation and plant development in Arabidopsis.

Q92506	DHB8_HUMAN	Estradiol 17-beta-dehydrogenase 8	19571038	17beta-Hydroxysteroid dehydrogenase type 8 and carbonyl reductase type 4 assemble as a ketoacyl reductase of human mitochondrial FAS.

Q9XTB5	LEM2_CAEEL	LEM protein 2	12684533	MAN1 and emerin have overlapping function(s) essential for chromosome segregation and cell division in Caenorhabditis elegans.

Q9UBU9	NXF1_HUMAN	Nuclear RNA export factor 1	19165146	Adaptor Aly and co-adaptor Thoc5 function in the Tap-p15-mediated nuclear export of HSP70 mRNA.

P21807	PERI_RAT	Peripherin	8575457	Translation initiation and assembly of peripherin in cultured cells.

Q9WVQ0	PMFBP_MOUSE	Polyamine-modulated factor 1-binding protein 1	11468771	Characterization of a novel gene, sperm-tail-associated protein (Stap), in mouse post-meiotic testicular germ cells.

P36614	PPE1_SCHPO	Serine/threonine-protein phosphatase ppe1	12773390	The role of Ppe1/PP6 phosphatase for equal chromosome segregation in fission yeast kinetochore.

P84845	CT5A_CONSP	T-conotoxin sr5a	16297502	A biologically active hydrophobic T-1-conotoxin from the venom of Conus spurius.

Q03435	NHP10_YEAST	Non-histone protein 10	14562095	Global analysis of protein localization in budding yeast.

P28040	DPOA_SCHPO	DNA polymerase alpha catalytic subunit	15643072	Mcl1p is a polymerase alpha replication accessory factor important for S-phase DNA damage survival.

Q9H2K2	TNKS2_HUMAN	Tankyrase-2	11454873	TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpression.

Q9D1C2	CBY1_MOUSE	Protein chibby homolog 1	17403895	Chibby promotes adipocyte differentiation through inhibition of beta- catenin signaling.

Q8CF98	COL10_MOUSE	Collectin-10	12450124	Molecular cloning of mouse collectin liver 1.

Q9Y4G8	RPGF2_HUMAN	Rap guanine nucleotide exchange factor 2	10934204	Identification of guanine nucleotide exchange factors (GEFs) for the Rap1 GTPase. Regulation of MR-GEF by M-Ras-GTP interaction.

P23188	FURIN_MOUSE	Furin	9412467	Cytoskeletal protein ABP-280 directs the intracellular trafficking of furin and modulates proprotein processing in the endocytic pathway.

O96623	ARPC2_DICDI	Actin-related protein 2/3 complex subunit 2	17553489	Mutants in the Dictyostelium Arp2/3 complex and chemoattractant- induced actin polymerization.

Q63716	PRDX1_RAT	Peroxiredoxin-1	10535922	Crystal structure of a multifunctional 2-Cys peroxiredoxin heme- binding protein 23 kDa/proliferation-associated gene product.

O60266	ADCY3_HUMAN	Adenylate cyclase type 3	9920776	Molecular cloning of a full-length cDNA for human type 3 adenylyl cyclase and its expression in human islets.

Q9UPV9	TRAK1_HUMAN	Trafficking kinesin-binding protein 1	16630562	The atypical Rho GTPases Miro-1 and Miro-2 have essential roles in mitochondrial trafficking.

Q04679	ATNG_RAT	Sodium/potassium-transporting ATPase subunit gamma	11832419	Distribution and oligomeric association of splice forms of Na(+)- K(+)-ATPase regulatory gamma-subunit in rat kidney.

O95674	CDS2_HUMAN	Phosphatidate cytidylyltransferase 2	9806839	Isolation and chromosomal localization of two human CDP- diacylglycerol synthase (CDS) genes.

Q12262	MCM16_YEAST	Central kinetochore subunit MCM16	11782448	Ctf3p, the Mis6 budding yeast homolog, interacts with Mcm22p and Mcm16p at the yeast outer kinetochore.

P36620	ILVB_SCHPO	Acetolactate synthase, mitochondrial	8299177	Isolation and structure of an acetolactate synthase gene from Schizosaccharomyces pombe and complementation of the ilv2 mutation in Saccharomyces cerevisiae.

O43474	KLF4_HUMAN	Krueppel-like factor 4	9422764	Human EZF, a Kruppel-like zinc finger protein, is expressed in vascular endothelial cells and contains transcriptional activation and repression domains.

P08074	CBR2_MOUSE	Carbonyl reductase [NADPH] 2	8805511	Crystal structure of the ternary complex of mouse lung carbonyl reductase at 1.8-A resolution: the structural origin of coenzyme specificity in the short-chain dehydrogenase/reductase family.

Q24342	FNG_DROME	Fringe glycosyltransferase	10899003	The notch signalling regulator fringe acts in the Golgi apparatus and requires the glycosyltransferase signature motif DXD.

P70694	DHB5_MOUSE	Estradiol 17 beta-dehydrogenase 5	7737980	Molecular cloning and characterization of mouse estradiol 17 beta- dehydrogenase (A-specific), a member of the aldoketoreductase family.

P46940	IQGA1_HUMAN	Ras GTPase-activating-like protein IQGAP1	8670801	IQGAP1, a calmodulin-binding protein with a rasGAP-related domain, is a potential effector for cdc42Hs.

O15151	MDM4_HUMAN	Protein Mdm4	9226370	Isolation and identification of the human homolog of a new p53- binding protein, Mdmx.

P24522	GA45A_HUMAN	Growth arrest and DNA damage-inducible protein GADD45 alpha	12716909	CR6-interacting factor 1 interacts with Gadd45 family proteins and modulates the cell cycle.

Q12280	IQG1_YEAST	Ras GTPase-activating-like protein IQG1	9950677	The multiple roles of Cyk1p in the assembly and function of the actomyosin ring in budding yeast.

Q64028	PHC1_MOUSE	Polyhomeotic-like protein 1	10653359	A novel member of murine polycomb-group proteins, Sex comb on midleg homolog protein, is highly conserved, and interacts with RAE28/mph1 in vitro.

P38860	MTG2_YEAST	GTPase MTG2, mitochondrial	15591131	The yeast GTPase Mtg2p is required for mitochondrial translation and partially suppresses an rRNA methyltransferase mutant, mrm2.

Q1MTQ1	TEA2_SCHPO	Kinesin-like protein tea2	15177031	Tea2p kinesin is involved in spatial microtubule organization by transporting tip1p on microtubules.

Q80U72	SCRIB_MOUSE	Protein scribble homolog	16611247	Human scribble, a novel tumor suppressor identified as a target of high-risk HPV E6 for ubiquitin-mediated degradation, interacts with adenomatous polyposis coli.

Q03786	GNTK_YEAST	Probable gluconokinase	14562095	Global analysis of protein localization in budding yeast.

Q9Y6D9	MD1L1_HUMAN	Mitotic spindle assembly checkpoint protein MAD1	12006501	Crystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpoint.

A0AQW4	TCP12_ARATH	Transcription factor TCP12	17307924	Arabidopsis BRANCHED1 acts as an integrator of branching signals within axillary buds.

P02458	CO2A1_HUMAN	Collagen alpha-1(II) chain	7550321	Dominant mutations in the type II collagen gene, COL2A1, produce spondyloepimetaphyseal dysplasia, Strudwick type.

Q8IZH2	XRN1_HUMAN	5'-3' exoribonuclease 1	18172165	Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'.

P04775	SCN2A_RAT	Sodium channel protein type 2 subunit alpha	3754035	Existence of distinct sodium channel messenger RNAs in rat brain.

Q5SUE7	ADAD1_MOUSE	Adenosine deaminase domain-containing protein 1	15649457	Disruption of murine Tenr results in teratospermia and male infertility.

P37672	DLGD_ECOLI	2,3-diketo-L-gulonate reductase	14718529	A novel NAD-binding protein revealed by the crystal structure of 2,3- diketo-L-gulonate reductase (YiaK).

P81002	GVP17_DACSA	17 kDa gas vesicle protein C	1527496	The homologies of gas vesicle proteins.

P21926	CD9_HUMAN	CD9 antigen	14575715	Structural requirements for the inhibitory action of the CD9 large extracellular domain in sperm/oocyte binding and fusion.

Q62762	KC1G2_RAT	Casein kinase I isoform gamma-2	7759525	Casein kinase I gamma subfamily. Molecular cloning, expression, and characterization of three mammalian isoforms and complementation of defects in the Saccharomyces cerevisiae YCK genes.

O13988	POT1_SCHPO	Protection of telomeres protein 1	12463756	Cooperative binding of single-stranded telomeric DNA by the Pot1 protein of Schizosaccharomyces pombe.

Q9Y5Z6	B3GT1_HUMAN	Beta-1,3-galactosyltransferase 1	9582303	A family of human beta3-galactosyltransferases. Characterization of four members of a UDP-galactose:beta-N-acetyl-glucosamine/beta- nacetyl-galactosamine beta-1,3-galactosyltransferase family.

P43557	FMP32_YEAST	Protein FMP32, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q9NR77	PXMP2_HUMAN	Peroxisomal membrane protein 2	16683188	The zinc containing pro-apoptotic protein siva interacts with the peroxisomal membrane protein pmp22.

Q8NEY3	SPAT4_HUMAN	Spermatogenesis-associated protein 4	12019456	Rapid identification of human testis spermatocyte apoptosis-related gene, TSARG2, by nested PCR and draft human genome searching.

P23895	EMRE_ECOLI	Multidrug transporter emrE	9688273	NMR investigation of the multidrug transporter EmrE, an integral membrane protein.

P40749	SYT4_MOUSE	Synaptotagmin-4	8058779	A third synaptotagmin gene, Syt3, in the mouse.

Q9PTH3	IBP2A_DANRE	Insulin-like growth factor-binding protein 2-A	10611375	Insulin-like growth factor binding protein 2 is a growth inhibitory protein conserved in zebrafish.

Q8L4D8	IQD31_ARATH	Protein IQ-DOMAIN 31	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

P93834	HXK2_ARATH	Hexokinase-2	9014361	Hexokinase as a sugar sensor in higher plants.

P54920	SNAA_HUMAN	Alpha-soluble NSF attachment protein	15029241	Implication of ZW10 in membrane trafficking between the endoplasmic reticulum and Golgi.

O74434	MU174_SCHPO	Meiotically up-regulated gene 174 protein	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

O13716	AGN1_SCHPO	Glucan endo-1,3-alpha-glucosidase agn1	15194814	Role of the alpha-glucanase Agn1p in fission-yeast cell separation.

Q14CW9	AT7L3_HUMAN	Ataxin-7-like protein 3	18206972	A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing.

P36999	RLMA_ECOLI	Ribosomal RNA large subunit methyltransferase A	9440525	Identification of the rrmA gene encoding the 23S rRNA m1G745 methyltransferase in Escherichia coli and characterization of an m1G745-deficient mutant.

P53267	DAM1_YEAST	DASH complex subunit DAM1	12925767	Kinetochore protein interactions and their regulation by the Aurora kinase Ipl1p.

P29034	S10A2_HUMAN	Protein S100-A2	9481475	Repression of the candidate tumor suppressor gene S100A2 in breast cancer is mediated by site-specific hypermethylation.

P15723	DGTP_ECOLI	Deoxyguanosinetriphosphate triphosphohydrolase	2826481	The purification and properties of deoxyguanosine triphosphate triphosphohydrolase from Escherichia coli.

P15090	FABP4_HUMAN	Fatty acid-binding protein, adipocyte	2481498	Human adipocyte lipid-binding protein: purification of the protein and cloning of its complementary DNA.

P43004	EAA2_HUMAN	Excitatory amino acid transporter 2	7521911	Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex.

Q7Z434	MAVS_HUMAN	Mitochondrial antiviral-signaling protein	16177806	Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus.

Q9Z2Q6	SEPT5_MOUSE	Septin-5	11739749	The septin CDCrel-1 is dispensable for normal development and neurotransmitter release.

Q15427	SF3B4_HUMAN	Splicing factor 3B subunit 4	7958871	The prespliceosome components SAP 49 and SAP 145 interact in a complex implicated in tethering U2 snRNP to the branch site.

Q08818	MSC6_YEAST	Meiotic sister-chromatid recombination protein 6, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

O75340	PDCD6_HUMAN	Programmed cell death protein 6	11883899	Both ALG-2 and peflin, penta-EF-hand (PEF) proteins, are stabilized by dimerization through their fifth EF-hand regions.

P34221	PP2C3_YEAST	Protein phosphatase 2C homolog 3	10580002	Dephosphorylation of cyclin-dependent kinases by type 2C protein phosphatases.

Q12016	VPS68_YEAST	Vacuolar protein sorting-associated protein 68	12134085	Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae.

P34241	URB1_YEAST	Nucleolar pre-ribosomal-associated protein 1	14562095	Global analysis of protein localization in budding yeast.

P51690	ARSE_HUMAN	Arylsulfatase E	7720070	A cluster of sulfatase genes on Xp22.3: mutations in chondrodysplasia punctata (CDPX) and implications for warfarin embryopathy.

Q9HDC5	JPH1_HUMAN	Junctophilin-1	10891348	Characterization of human junctophilin subtype genes.

Q6P1M0	S27A4_HUMAN	Long-chain fatty acid transport protein 4	9878842	Tissue distribution and cDNA cloning of a human fatty acid transport protein (hsFATP4).

Q9D424	CABYR_MOUSE	Calcium-binding tyrosine phosphorylation-regulated protein	17855365	FSCB, a novel protein kinase A-phosphorylated calcium-binding protein, is a CABYR-binding partner involved in late steps of fibrous sheath biogenesis.

Q91989	P5F13_XENLA	POU domain, class 5, transcription factor 1.3	17541407	POU-V factors antagonize maternal VegT activity and beta-Catenin signaling in Xenopus embryos.

Q9FHK4	Y5519_ARATH	Uncharacterized protein At5g05190	15618630	Identification of three clones which commonly interact with the kinase domains of highly homologous two receptor-like kinases, RLK902 and RKL1.

Q9UGJ0	AAKG2_HUMAN	5'-AMP-activated protein kinase subunit gamma-2	11827995	Constitutively active AMP kinase mutations cause glycogen storage disease mimicking hypertrophic cardiomyopathy.

Q15699	ALX1_HUMAN	ALX homeobox protein 1	8756334	Human Cart-1: structural organization, chromosomal localization, and functional analysis of a cartilage-specific homeodomain cDNA.

Q63065	PDK1_RAT	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial	8253790	Primary structure of pyruvate dehydrogenase kinase establishes a new family of eukaryotic protein kinases.

Q50755	HDRB_METTM	CoB--CoM heterodisulfide reductase subunit B	2121478	Purification and properties of heterodisulfide reductase from Methanobacterium thermoautotrophicum (strain Marburg).

Q42588	SAT1_ARATH	Serine acetyltransferase 1, chloroplastic	9830017	Isoform-dependent differences in feedback regulation and subcellular localization of serine acetyltransferase involved in cysteine biosynthesis from Arabidopsis thaliana.

P01160	ANF_HUMAN	Atrial natriuretic factor	1672777	Selective activation of the B natriuretic peptide receptor by C-type natriuretic peptide (CNP).

P40030	ERG28_YEAST	Ergosterol biosynthetic protein 28	11160377	A novel gene conserved from yeast to humans is involved in sterol biosynthesis.

Q90ZH8	SX18A_XENLA	Transcription factor Sox-18A	12062811	Expression and characterization of Xenopus laevis SRY-related cDNAs, xSox17alpha1, xSox17alpha2, xSox18alpha and xSox18beta.

Q9UST6	SPC24_SCHPO	Kinetochore protein spc24	16079914	Molecular analysis of kinetochore architecture in fission yeast.

P09565	IG2R_HUMAN	Putative insulin-like growth factor 2-associated protein	3167054	Differential expression of the human insulin-like growth factor II gene. Characterization of the IGF-II mRNAs and an mRNA encoding a putative IGF-II-associated protein.

Q9P7R5	GFH1_SCHPO	Gamma-tubulin complex component gfh1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8WX93	PALLD_HUMAN	Palladin	16125169	Involvement of palladin and alpha-actinin in targeting of the Abl/Arg kinase adaptor ArgBP2 to the actin cytoskeleton.

P25846	MSH1_YEAST	DNA mismatch repair protein MSH1, mitochondrial	7961998	Purification and characterization of MSH1, a yeast mitochondrial protein that binds to DNA mismatches.

Q64537	CPNS1_RAT	Calpain small subunit 1	15476820	Activation of calpain by Ca2+: roles of the large subunit N-terminal and domain III-IV linker peptides.

P02365	RS6_YEAST	40S ribosomal protein S6	6814480	Isolation of seventeen proteins and amino-terminal amino acid sequences of eight proteins from cytoplasmic ribosomes of yeast.

B7ZS96	TTHY_XENLA	Transthyretin	15590892	In vitro and in vivo analysis of the thyroid disrupting activities of phenolic and phenol compounds in Xenopus laevis.

O60729	CC14B_HUMAN	Dual specificity protein phosphatase CDC14B	18662541	The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint.

Q9FN52	MAM3_ARATH	Methylthioalkylmalate synthase 3, chloroplastic	15155874	Glucosinolate and amino acid biosynthesis in Arabidopsis.

Q39214	RPM1_ARATH	Disease resistance protein RPM1	11955429	RIN4 interacts with Pseudomonas syringae type III effector molecules and is required for RPM1-mediated resistance in Arabidopsis.

P12904	SNF4_YEAST	Nuclear protein SNF4	2481228	Molecular analysis of the SNF4 gene of Saccharomyces cerevisiae: evidence for physical association of the SNF4 protein with the SNF1 protein kinase.

Q9Y6K8	KAD5_HUMAN	Adenylate kinase isoenzyme 5	10215863	Identification of a novel human adenylate kinase. cDNA cloning, expression analysis, chromosome localization and characterization of the recombinant protein.

Q60575	KIF1B_MOUSE	Kinesin-like protein KIF1B	10571041	A novel kinesin of the UNC-104/KIF1 subfamily encoded by the Kif1b gene.

P30533	AMRP_HUMAN	Alpha-2-macroglobulin receptor-associated protein	1712782	Primary structure of alpha 2-macroglobulin receptor-associated protein. Human homologue of a Heymann nephritis antigen.

Q9H3N1	TMX1_HUMAN	Thioredoxin-related transmembrane protein 1	11152479	Identification of a novel thioredoxin-related transmembrane protein.

P32387	RM41_YEAST	54S ribosomal protein L41, mitochondrial	9151978	Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae.

O08617	PTPRR_RAT	Receptor-type tyrosine-protein phosphatase R	7814416	A neuronal protein tyrosine phosphatase induced by nerve growth factor.

P37398	VIV_ORYSJ	B3 domain-containing protein VP1	8193305	Sequence and functional analyses of the rice gene homologous to the maize Vp1.

P38929	ATC2_YEAST	Calcium-transporting ATPase 2	7507493	Calcineurin-dependent growth control in Saccharomyces cerevisiae mutants lacking PMC1, a homolog of plasma membrane Ca2+ ATPases.

Q9U8Q4	PRSN_PIERA	Pierisin	11592983	Mono(ADP-ribosyl)ation of 2'-deoxyguanosine residue in DNA by an apoptosis-inducing protein, pierisin-1, from cabbage butterfly.

P16112	PGCA_HUMAN	Aggrecan core protein	17588949	Interaction of cartilage oligomeric matrix protein/thrombospondin 5 with aggrecan.

O80501	RBH1B_ARATH	Ras-related protein RABH1B	8159788	A small GTP-binding protein from Arabidopsis thaliana functionally complements the yeast YPT6 null mutant.

Q9JIM0	MRE11_RAT	Double-strand break repair protein MRE11A	10908350	The MRE11-NBS1-RAD50 pathway is perturbed in SV40 large T antigen- immortalized AT-1, AT-2 and HL-1 cardiomyocytes.

P38741	RIM4_YEAST	Meiotic activator RIM4	10806425	An RNA-binding protein homologue that promotes sporulation-specific gene expression in Saccharomyces cerevisiae.

Q9BZJ0	CRNL1_HUMAN	Crooked neck-like protein 1	11991638	Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.

Q99JZ7	ERRFI_MOUSE	ERBB receptor feedback inhibitor 1	16648858	Mig6 is a negative regulator of EGF receptor-mediated skin morphogenesis and tumor formation.

Q9P7C8	SLD5_SCHPO	DNA replication complex GINS protein sld5	16199877	Suppressors of Bir1p (Survivin) identify roles for the chromosomal passenger protein Pic1p (INCENP) and the replication initiation factor Psf2p in chromosome segregation.

Q5VMP0	MAX2_ORYSJ	F-box/LRR-repeat MAX2 homolog	15659436	Suppression of tiller bud activity in tillering dwarf mutants of rice.

P36017	VPS21_YEAST	Vacuolar protein sorting-associated protein 21	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q922J9	FACR1_MOUSE	Fatty acyl-CoA reductase 1	15220349	Mammalian wax biosynthesis. II. Expression cloning of wax synthase cDNAs encoding a member of the acyltransferase enzyme family.

P35996	RM38_YEAST	54S ribosomal protein L38, mitochondrial	9151978	Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae.

O15524	SOCS1_HUMAN	Suppressor of cytokine signaling 1	9202126	A new protein containing an SH2 domain that inhibits JAK kinases.

P53725	MPP6_YEAST	M-phase phosphoprotein 6 homolog	16702403	Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes.

P39722	GEM1_YEAST	Mitochondrial Rho GTPase 1	10220001	The open reading frame YAL048c affects the secretion of proteinase A in S. cerevisiae.

P33418	XPOT_YEAST	Exportin-T	8366091	The Saccharomyces cerevisiae LOS1 gene involved in pre-tRNA splicing encodes a nuclear protein that behaves as a component of the nuclear matrix.

Q9Y450	HBS1L_HUMAN	HBS1-like protein	9872408	The product of the mammalian orthologue of the Saccharomyces cerevisiae HBS1 gene is phylogenetically related to eukaryotic release factor 3 (eRF3) but does not carry eRF3-like activity.

Q6PHH3	PD10A_DANRE	Programmed cell death protein 10-A	19370760	Functional analyses of human and zebrafish 18-amino acid in-frame deletion pave the way for domain mapping of the cerebral cavernous malformation 3 protein.

Q61345	FOXD1_MOUSE	Forkhead box protein D1	15634693	Foxd1-dependent signals control cellularity in the renal capsule, a structure required for normal renal development.

Q03266	PABC_YEAST	Aminodeoxychorismate lyase	14562095	Global analysis of protein localization in budding yeast.

A2A935	PRD16_MOUSE	PR domain zinc finger protein 16	17467076	PRDM16/MEL1: a novel Smad binding protein expressed in murine embryonic orofacial tissue.

Q8GYB8	OPR2_ARATH	12-oxophytodienoate reductase 2	10872231	12-Oxophytodienoate reductase 3 (OPR3) is the isoenzyme involved in jasmonate biosynthesis.

Q79PF4	KAIC_SYNE7	Circadian clock protein kinase kaiC	10786837	A kaiC-interacting sensory histidine kinase, SasA, necessary to sustain robust circadian oscillation in cyanobacteria.

Q9P3U8	YJ95_SCHPO	Uncharacterized RING finger protein C548.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P23437	CDK2_XENLA	Cell division protein kinase 2	10202150	Speedy: a novel cell cycle regulator of the G2/M transition.

P24057	ARLY1_ANAPL	Delta-1 crystallin	11258884	Structural studies of duck delta 1 and delta 2 crystallin suggest conformational changes occur during catalysis.

Q8AXX8	SOX10_XENLA	Transcription factor Sox-10	12885557	Sox10 is required for the early development of the prospective neural crest in Xenopus embryos.

P14209	CD99_HUMAN	CD99 antigen	2479542	The E2 antigen, a 32 kd glycoprotein involved in T-cell adhesion processes, is the MIC2 gene product.

Q01196	RUNX1_HUMAN	Runt-related transcription factor 1	10856244	Structural basis for the heterodimeric interaction between the acute leukaemia-associated transcription factors AML1 and CBFbeta.

P40160	RIO2_YEAST	Serine/threonine-protein kinase RIO2	12690111	Rio2p, an evolutionarily conserved, low abundant protein kinase essential for processing of 20 S pre-rRNA in Saccharomyces cerevisiae.

Q21227	APR1_CAEEL	Adenomatous polyposis coli protein-related protein 1	12023307	The axin-like protein PRY-1 is a negative regulator of a canonical Wnt pathway in C. elegans.

Q9NZM1	MYOF_HUMAN	Myoferlin	10607832	Myoferlin, a candidate gene and potential modifier of muscular dystrophy.

P36605	HIS8_SCHPO	Histidinol-phosphate aminotransferase	8159167	Molecular cloning and characterization of the Schizosaccharomyces pombe his3 gene for use as a selectable marker.

P70503	NR0B1_RAT	Nuclear receptor subfamily 0 group B member 1	8754790	Differential patterns of expression of DAX-1 and steroidogenic factor-1 (SF-1) in the fetal rat testis.

Q9FMW9	ICMTA_ARATH	Protein-S-isoprenylcysteine O-methyltransferase A	11352465	Identification and functional expression in yeast of a prenylcysteine alpha-carboxyl methyltransferase gene from Arabidopsis thaliana.

Q9HB58	SP110_HUMAN	Sp110 nuclear body protein	7693701	Molecular cloning of two new interferon-induced, highly related nuclear phosphoproteins.

O14907	TX1B3_HUMAN	Tax1-binding protein 3	10940294	The PDZ protein TIP-1 interacts with the Rho effector rhotekin and is involved in Rho signaling to the serum response element.

P49792	RBP2_HUMAN	E3 SUMO-protein ligase RanBP2	16332688	Parkin ubiquitinates and promotes the degradation of RanBP2.

Q505F1	NR2C1_MOUSE	Nuclear receptor subfamily 2 group C member 1	9369481	The orphan nuclear receptor TR2 suppresses a DR4 hormone response element of the mouse CRABP-I gene promoter.

Q9YHC5	FOXG1_XENLA	Forkhead box protein G1	15656969	Of fox and frogs: fox (fork head/winged helix) transcription factors in Xenopus development.

Q9ZVH4	CUL3A_ARATH	Cullin-3A	15772280	Arabidopsis has two redundant Cullin3 proteins that are essential for embryo development and that interact with RBX1 and BTB proteins to form multisubunit E3 ubiquitin ligase complexes in vivo.

Q8BUZ1	ABRA_MOUSE	Actin-binding Rho-activating protein	17194709	Two novel members of the ABLIM protein family, ABLIM-2 and -3, associate with STARS and directly bind F-actin.

P17157	PHO85_YEAST	Cyclin-dependent protein kinase PHO85	8108735	Phosphorylation of the transcription factor PHO4 by a cyclin-CDK complex, PHO80-PHO85.

Q09752	FNX1_SCHPO	Multidrug resistance protein fnx1	9710608	The role of fnx1, a fission yeast multidrug resistance protein, in the transition of cells to a quiescent G0 state.

Q9LE59	GAUT1_ARATH	Alpha-1,4-galacturonosyltransferase 1	16540543	Functional identification of an Arabidopsis pectin biosynthetic homogalacturonan galacturonosyltransferase.

P70061	NKX32_XENLA	Homeobox protein Nkx-3.2	9013932	Xbap, a vertebrate gene related to bagpipe, is expressed in developing craniofacial structures and in anterior gut muscle.

Q8VI88	ODFP4_MOUSE	Outer dense fiber protein 4	12079992	Molecular cloning and characterization of Oppo 1: a haploid germ cell-specific complementary DNA encoding sperm tail protein.

Q9YGV1	DERR_XENLA	Derriere protein	10068640	derriere: a TGF-beta family member required for posterior development in Xenopus.

O43405	COCH_HUMAN	Cochlin	9806553	Mutations in a novel cochlear gene cause DFNA9, a human nonsyndromic deafness with vestibular dysfunction.

P11412	G6PD_YEAST	Glucose-6-phosphate 1-dehydrogenase	2269430	Isolation and characterization of the ZWF1 gene of Saccharomyces cerevisiae, encoding glucose-6-phosphate dehydrogenase.

Q9Y4K3	TRAF6_HUMAN	TNF receptor-associated factor 6	17135271	Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation.

P49445	PTN7_RAT	Tyrosine-protein phosphatase non-receptor type 7	7545170	Aggregation of IgE receptors in rat basophilic leukemia 2H3 cells induces tyrosine phosphorylation of the cytosolic protein-tyrosine phosphatase HePTP.

P62380	TBPL1_HUMAN	TATA box-binding protein-like protein 1	10220372	TATA box-binding protein (TBP)-related factor 2 (TRF2), a third member of the TBP family.

P24033	CDK1B_XENLA	Cell division protein kinase 1-B	15611625	Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins.

Q91689	ZIC2A_XENLA	Zinc finger protein ZIC 2-A	9634234	Gli/Zic factors pattern the neural plate by defining domains of cell differentiation.

Q1K9C4	YFK7_SCHPO	Probable E3 ubiquitin protein ligase C167.07c	12529438	Global transcriptional responses of fission yeast to environmental stress.

Q9YGG9	MMHA_AGKHA	Mamushigin subunit alpha	9657448	The cDNA cloning and molecular characterization of a snake venom platelet glycoprotein Ib-binding protein, mamushigin, from Agkistrodon halys blomhoffii venom.

Q9WVH8	FBLN5_RAT	Fibulin-5	10428823	DANCE, a novel secreted RGD protein expressed in developing, atherosclerotic, and balloon-injured arteries.

Q06449	PIN3_YEAST	[PSI+] inducibility protein 3	14562095	Global analysis of protein localization in budding yeast.

O43524	FOXO3_HUMAN	Forkhead box protein O3	16751106	A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span.

Q04767	TVP18_YEAST	Golgi apparatus membrane protein TVP18	16107716	Immunoisolaton of the yeast Golgi subcompartments and characterization of a novel membrane protein, Svp26, discovered in the Sed5-containing compartments.

Q9NPJ4	PNRC2_HUMAN	Proline-rich nuclear receptor coactivator 2	19150429	Human proline-rich nuclear receptor coregulatory protein 2 mediates an interaction between mRNA surveillance machinery and decapping complex.

Q9P6K3	YLF8_SCHPO	UPF0662 protein C30C2.08	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q13094	LCP2_HUMAN	Lymphocyte cytosolic protein 2	7706237	Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells.

Q86B87	MMD4_DROME	Modifier of mdg4	16209949	The ubiquitin ligase dTopors directs the nuclear organization of a chromatin insulator.

P04156	PRIO_HUMAN	Major prion protein	11900542	Molecular features of the copper binding sites in the octarepeat domain of the prion protein.

Q9UBN4	TRPC4_HUMAN	Short transient receptor potential channel 4	8646775	trp, a novel mammalian gene family essential for agonist-activated capacitative Ca2+ entry.

Q15121	PEA15_HUMAN	Astrocytic phosphoprotein PEA-15	10442631	PED/PEA-15: an anti-apoptotic molecule that regulates FAS/TNFR1- induced apoptosis.

Q8LG77	IDH6_ARATH	Isocitrate dehydrogenase [NAD] catalytic subunit 6, mitochondrial	16527867	Expression analysis of Arabidopsis thaliana NAD-dependent isocitrate dehydrogenase genes shows the presence of a functional subunit that is mainly expressed in the pollen and absent from vegetative organs.

Q9C500	WPP2_ARATH	WPP domain-containing protein 2	15548735	Arabidopsis WPP-domain proteins are developmentally associated with the nuclear envelope and promote cell division.

Q8GV05	TRY_ARATH	Transcription factor TRY	14561633	A contradictory GLABRA3 allele helps define gene interactions controlling trichome development in Arabidopsis.

Q9M1S8	GCP2_ARATH	Probable glutamate carboxypeptidase 2	17553903	AMP1 and MP antagonistically regulate embryo and meristem development in Arabidopsis.

Q08886	GPB1_YEAST	Guanine nucleotide-binding protein subunit beta 1	14562095	Global analysis of protein localization in budding yeast.

P84639	CYVC_LEOCM	Cycloviolin-C	10813905	Cycloviolins A-D, anti-HIV macrocyclic peptides from Leonia cymosa.

P40344	ATG3_YEAST	Autophagy-related protein 3	15277523	In vivo and in vitro reconstitution of atg8 conjugation essential for autophagy.

O35412	SI1L1_RAT	Signal-induced proliferation-associated 1-like protein 1	16522626	ProSAP-interacting protein 1 (ProSAPiP1), a novel protein of the postsynaptic density that links the spine-associated Rap-Gap (SPAR) to the scaffolding protein ProSAP2/Shank3.

P21707	SYT1_RAT	Synaptotagmin-1	2333096	Phospholipid binding by a synaptic vesicle protein homologous to the regulatory region of protein kinase C.

P47074	MAD3_YEAST	Spindle assembly checkpoint component MAD3	10704439	MAD3 encodes a novel component of the spindle checkpoint which interacts with Bub3p, Cdc20p, and Mad2p.

Q92879	CELF1_HUMAN	CUGBP Elav-like family member 1	14726956	Competition of CUGBP1 and calreticulin for the regulation of p21 translation determines cell fate.

Q92207	HOG1_CANAL	Mitogen-activated protein kinase HOG1	16079350	The MAP kinase Mkc1p is activated under different stress conditions in Candida albicans.

Q03414	MEF2A_XENLA	Myocyte-specific enhancer factor 2A homolog	17785444	Nemo-like kinase-myocyte enhancer factor 2A signaling regulates anterior formation in Xenopus development.

P47047	MTR4_YEAST	ATP-dependent RNA helicase DOB1	15828860	A new yeast poly(A) polymerase complex involved in RNA quality control.

P61312	ADM2_RAT	ADM2	14615490	Intermedin is a calcitonin/calcitonin gene-related peptide family peptide acting through the calcitonin receptor-like receptor/receptor activity-modifying protein receptor complexes.

P15260	INGR1_HUMAN	Interferon gamma receptor 1	2971451	Molecular cloning and expression of the human interferon-gamma receptor.

Q14410	GLPK2_HUMAN	Glycerol kinase 2	7987308	The glycerol kinase gene family: structure of the Xp gene, and related intronless retroposons.

O95749	GGPPS_HUMAN	Geranylgeranyl pyrophosphate synthase	9741684	Human geranylgeranyl diphosphate synthase: isolation of the cDNA, chromosomal mapping and tissue expression.

Q90WP7	PLR_RANPI	Peptide leucine arginine	11099505	Peptide leucine arginine, a potent immunomodulatory peptide, isolated and structurally characterized from the skin of the Northern Leopard frog, Rana pipiens.

Q9R0X4	ACOT9_MOUSE	Acyl-coenzyme A thioesterase 9, mitochondrial	10383425	Molecular cloning and characterization of MT-ACT48, a novel mitochondrial acyl-CoA thioesterase.

P41738	AHR_RAT	Aryl hydrocarbon receptor	7812217	Dioxin-dependent, DNA sequence-specific binding of a multiprotein complex containing the Ah receptor.

P40227	TCPZ_HUMAN	T-complex protein 1 subunit zeta	8034610	Tcp20, a subunit of the eukaryotic TRiC chaperonin from humans and yeast.

O94519	SPF30_SCHPO	Splicing factor spf30	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12172	YRR1_YEAST	Zinc finger transcription factor YRR1	9767597	Yeast gene YRR1, which is required for resistance to 4-nitroquinoline N-oxide, mediates transcriptional activation of the multidrug resistance transporter gene SNQ2.

Q9C0V1	AMT1_SCHPO	Ammonium transporter 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P38144	ISW1_YEAST	ISWI chromatin-remodeling complex ATPase ISW1	12482963	Yeast Isw1p forms two separable complexes in vivo.

Q95SX7	RTBS_DROME	Probable RNA-directed DNA polymerase from transposon BS	7753626	BS a novel LINE-like element in Drosophila melanogaster.

Q68A21	PURB_RAT	Transcriptional activator protein Pur-beta	12933792	Single-stranded DNA-binding proteins PURalpha and PURbeta bind to a purine-rich negative regulatory element of the alpha-myosin heavy chain gene and control transcriptional and translational regulation of the gene expression. Implications in the repression of alpha-myosin heavy chain during heart failure.

Q9NP58	ABCB6_HUMAN	ATP-binding cassette sub-family B member 6, mitochondrial	10837493	MTABC3, a novel mitochondrial ATP-binding cassette protein involved in iron homeostasis.

Q13352	CENPR_HUMAN	Centromere protein R	7593198	Beta 3-endonexin, a novel polypeptide that interacts specifically with the cytoplasmic tail of the integrin beta 3 subunit.

Q96QV1	HHIP_HUMAN	Hedgehog-interacting protein	19561609	The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling.

Q9WUS4	CXA10_MOUSE	Gap junction alpha-10 protein	10329667	Molecular cloning and functional expression of the mouse gap junction gene connexin-57 in human HeLa cells.

Q8W191	HYH_ARATH	Transcription factor HY5-like	12023303	Two interacting bZIP proteins are direct targets of COP1-mediated control of light-dependent gene expression in Arabidopsis.

Q03280	TOM1_YEAST	E3 ubiquitin-protein ligase TOM1	10395901	Yeast tom1 mutant exhibits pleiotropic defects in nuclear division, maintenance of nuclear structure and nucleocytoplasmic transport at high temperatures.

Q6ZDF3	TRAB1_ORYSJ	bZIP transcription factor TRAB1	10611387	A bZIP factor, TRAB1, interacts with VP1 and mediates abscisic acid- induced transcription.

P53327	SLH1_YEAST	Antiviral helicase SLH1	14562095	Global analysis of protein localization in budding yeast.

Q06216	PIG1_YEAST	Serine/threonine-protein phosphatase 1 regulatory subunit PIG1	9046081	Yeast PIG genes: PIG1 encodes a putative type 1 phosphatase subunit that interacts with the yeast glycogen synthase Gsy2p.

Q04835	YM87_YEAST	Uncharacterized membrane protein YMR253C	14562095	Global analysis of protein localization in budding yeast.

Q53HL2	BOREA_HUMAN	Borealin	17956729	Structure of a Survivin-Borealin-INCENP core complex reveals how chromosomal passengers travel together.

O75369	FLNB_HUMAN	Filamin-B	8327473	Cloning from the thyroid of a protein related to actin binding protein that is recognized by Graves disease immunoglobulins.

P19474	RO52_HUMAN	E3 ubiquitin-protein ligase TRIM21	19675099	Ro52-mediated monoubiquitination of IKK{beta} down-regulates NF-{kappa}B signalling.

Q8IN44	TOTA_DROME	Protein Turandot A	12967563	Signaling role of hemocytes in Drosophila JAK/STAT-dependent response to septic injury.

O43707	ACTN4_HUMAN	Alpha-actinin-4	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

Q9P107	GMIP_HUMAN	GEM-interacting protein	12093360	A novel Rho GTPase-activating-protein interacts with Gem, a member of the Ras superfamily of GTPases.

Q95UN8	M3KSL_DROME	Mitogen-activated protein kinase kinase kinase	11825878	Activation of the JNK pathway during dorsal closure in Drosophila requires the mixed lineage kinase, slipper.

P30825	CTR1_HUMAN	High affinity cationic amino acid transporter 1	1718082	Molecular cloning and characterization of a novel human gene homologous to the murine ecotropic retroviral receptor.

P22265	TSH_DROME	Protein teashirt	15936749	A critical role of teashirt for patterning the ventral epidermis is masked by ectopic expression of tiptop, a paralog of teashirt in Drosophila.

Q96D31	CRCM1_HUMAN	Calcium release-activated calcium channel protein 1	16766533	Orai1 and STIM reconstitute store-operated calcium channel function.

Q62803	HYALP_RAT	Hyaluronidase PH-20	8914077	Molecular cloning and characterization of rat sperm surface antigen 2B1, a glycoprotein implicated in sperm-zona binding.

P49573	CTR1_YEAST	Copper transport protein CTR1	7929270	The Saccharomyces cerevisiae copper transport protein (Ctr1p). Biochemical characterization, regulation by copper, and physiologic role in copper uptake.

Q12366	NDJ1_YEAST	Non-disjunction protein 1	16648465	Ndj1, a telomere-associated protein, promotes meiotic recombination in budding yeast.

P19429	TNNI3_HUMAN	Troponin I, cardiac muscle	11815426	Sarcomere protein gene mutations in hypertrophic cardiomyopathy of the elderly.

Q00653	NFKB2_HUMAN	Nuclear factor NF-kappa-B p100 subunit	8360178	Purification of the major histocompatibility complex class I transcription factor H2TF1. The full-length product of the nfkb2 gene.

P09798	CDC16_YEAST	Anaphase-promoting complex subunit CDC16	11114178	Ama1p is a meiosis-specific regulator of the anaphase promoting complex/cyclosome in yeast.

Q09761	SLD3_SCHPO	DNA replication regulator sld3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NZJ0	DTL_HUMAN	Denticleless protein homolog	17106265	Role of L2DTL, cell cycle-regulated nuclear and centrosome protein, in aggressive hepatocellular carcinoma.

Q9JHZ9	S38A3_RAT	Sodium-coupled neutral amino acid transporter 3	10619430	Molecular analysis of system N suggests novel physiological roles in nitrogen metabolism and synaptic transmission.

Q15650	TRIP4_HUMAN	Activating signal cointegrator 1	7776974	Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor.

P14653	HXB1_HUMAN	Homeobox protein Hox-B1	10052460	Structure of a HoxB1-Pbx1 heterodimer bound to DNA: role of the hexapeptide and a fourth homeodomain helix in complex formation.

Q39227	SMT2_ARATH	24-methylenesterol C-methyltransferase 2	12215504	The identification of CVP1 reveals a role for sterols in vascular patterning.

Q9USK3	YJ2D_SCHPO	Uncharacterized transporter C4B3.13	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9EQC9	CXXC4_RAT	CXXC-type zinc finger protein 4	15313210	Interaction between the internal motif KTXXXI of Idax and mDvl PDZ domain.

Q9VW15	ASH1_DROME	Histone-lysine N-methyltransferase ash1	16497925	Noncoding RNAs of trithorax response elements recruit Drosophila Ash1 to Ultrabithorax.

P17553	WNT3_MOUSE	Proto-oncogene Wnt-3	19841259	Reciprocal regulation of Wnt and Gpr177/mouse Wntless is required for embryonic axis formation.

O55232	OREX_RAT	Orexin	9419374	The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity.

Q9FX01	HSDD1_ARATH	3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 1	16835224	Molecular and enzymatic characterizations of novel bifunctional 3beta-hydroxysteroid dehydrogenases/C-4 decarboxylases from Arabidopsis thaliana.

O74508	SPP1_SCHPO	Set1 complex component spp1	12488447	High conservation of the Set1/Rad6 axis of histone 3 lysine 4 methylation in budding and fission yeasts.

Q15796	SMAD2_HUMAN	Mothers against decapentaplegic homolog 2	9389648	Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes.

P36131	SPC34_YEAST	DASH complex subunit SPC34	15664196	Formation of a dynamic kinetochore-microtubule interface through assembly of the Dam1 ring complex.

Q03002	YP141_YEAST	Putative serine/threonine-protein kinase YPL141C	14562095	Global analysis of protein localization in budding yeast.

Q10113	MAL3_SCHPO	Microtubule integrity protein mal3	15665379	The EB1 homolog Mal3 stimulates the ATPase of the kinesin Tea2 by recruiting it to the microtubule.

Q09191	RPAB1_SCHPO	DNA-directed RNA polymerases I, II, and III subunit RPABC1	9499374	Molecular cloning of rpb5+, rpb7+ and rpb11+ genes of the fission yeast Schizosaccharomyces pombe: completing primary structure of all indispensable subunits of its RNA polymerase II.

P0CG76	UBIQA_DICDI	Polyubiquitin-A	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

Q04002	SCC2_YEAST	Sister chromatid cohesion protein 2	9990856	Yeast cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication.

P53900	PFD4_YEAST	Prefoldin subunit 4	9463374	A novel protein complex promoting formation of functional alpha- and gamma-tubulin.

P55345	ANM2_HUMAN	Protein arginine N-methyltransferase 2	12039952	Identification of protein arginine methyltransferase 2 as a coactivator for estrogen receptor alpha.

P43896	EFTS_BOVIN	Elongation factor Ts, mitochondrial	15557323	Crystal structure of the bovine mitochondrial elongation factor Tu.Ts complex.

Q06709	REH1_YEAST	Zinc finger protein REH1	14562095	Global analysis of protein localization in budding yeast.

O60469	DSCAM_HUMAN	Down syndrome cell adhesion molecule	19196994	DSCAM functions as a netrin receptor in commissural axon pathfinding.

Q6P0J3	SP8_DANRE	Transcription factor Sp8	15358670	Sp8 and Sp9, two closely related buttonhead-like transcription factors, regulate Fgf8 expression and limb outgrowth in vertebrate embryos.

P32479	HIR1_YEAST	Protein HIR1	11782447	Chromatin assembly factor I and Hir proteins contribute to building functional kinetochores in S. cerevisiae.

Q9NKV0	MLF_DROME	Myeloid leukemia factor	11137299	Characterization of a Drosophila homologue of the human myelodysplasia/myeloid leukemia factor (MLF).

O70212	5HT3A_CAVPO	5-hydroxytryptamine receptor 3A	9463477	Molecular cloning, functional expression, and pharmacological characterization of 5-hydroxytryptamine3 receptor cDNA and its splice variants from guinea pig.

Q8BTM8	FLNA_MOUSE	Filamin-A	9412467	Cytoskeletal protein ABP-280 directs the intracellular trafficking of furin and modulates proprotein processing in the endocytic pathway.

P17796	VIRB6_AGRT5	Protein virB6	2233252	Characterization of the virB operon of an Agrobacterium tumefaciens Ti plasmid: nucleotide sequence and protein analysis.

P63386	MLAF_ECOLI	Probable phospholipid import ATP-binding protein mlaF	19383799	An ABC transport system that maintains lipid asymmetry in the gram- negative outer membrane.

Q9Y6F6	MRVI1_HUMAN	Protein MRVI1	10321731	Mrvi1, a common MRV integration site in BXH2 myeloid leukemias, encodes a protein with homology to a lymphoid-restricted membrane protein Jaw1.

Q8BSP2	CNDH2_MOUSE	Condensin-2 complex subunit H2	17640884	A mutation in a chromosome condensin II subunit, kleisin beta, specifically disrupts T cell development.

Q05521	DPP1_YEAST	Diacylglycerol pyrophosphate phosphatase 1	8567632	Purification and characterization of diacylglycerol pyrophosphate phosphatase from Saccharomyces cerevisiae.

Q8RWN7	P2C32_ARATH	Protein phosphatase 2C 32	12573213	POLTERGEIST encodes a protein phosphatase 2C that regulates CLAVATA pathways controlling stem cell identity at Arabidopsis shoot and flower meristems.

P46367	ALDH4_YEAST	Potassium-activated aldehyde dehydrogenase, mitochondrial	9675847	Identification and disruption of the gene encoding the K(+)-activated acetaldehyde dehydrogenase of Saccharomyces cerevisiae.

Q7TNB2	TNNT1_RAT	Troponin T, slow skeletal muscle	15788488	Expression and functional properties of four slow skeletal troponin T isoforms in rat muscles.

Q54IL5	UGT52_DICDI	UDP-sugar-dependent glycosyltransferase 52	10224056	Cloning and functional expression of UGT genes encoding sterol glucosyltransferases from Saccharomyces cerevisiae, Candida albicans, Pichia pastoris, and Dictyostelium discoideum.

Q9BVC4	LST8_HUMAN	Target of rapamycin complex subunit LST8	12408816	Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control.

Q9UM11	FZR_HUMAN	Fizzy-related protein homolog	18662541	The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint.

Q9UT49	CID13_SCHPO	Poly(A) RNA polymerase cid13	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q06510	TAZ1_YEAST	Lysophosphatidylcholine acyltransferase	16135531	Taz1, an outer mitochondrial membrane protein, affects stability and assembly of inner membrane protein complexes: implications for Barth Syndrome.

Q5UKY4	MO2R3_MOUSE	Cell surface glycoprotein CD200 receptor 3	15274657	Structural and functional heterogeneity in the CD200R family of immunoregulatory molecules and their expression at the feto-maternal interface.

O80963	ACCR2_ARATH	Serine/threonine-protein kinase-like protein CCR2	15549374	Molecular analysis of the CRINKLY4 gene family in Arabidopsis thaliana.

O64973	RPS5_ARATH	Disease resistance protein RPS5	9724691	A mutation within the leucine-rich repeat domain of the Arabidopsis disease resistance gene RPS5 partially suppresses multiple bacterial and downy mildew resistance genes.

Q05779	COQ9_YEAST	Ubiquinone biosynthesis protein COQ9, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

P53039	YIP1_YEAST	Protein transport protein YIP1	9724632	Specific binding to a novel and essential Golgi membrane protein (Yip1p) functionally links the transport GTPases Ypt1p and Ypt31p.

P43341	LPXH_ECOLI	UDP-2,3-diacylglucosamine hydrolase	12000770	The Escherichia coli gene encoding the UDP-2,3-diacylglucosamine pyrophosphatase of lipid A biosynthesis.

Q9NQT4	EXOS5_HUMAN	Exosome complex exonuclease RRP46	11812149	Protein-protein interactions of hCsl4p with other human exosome subunits.

Q9Y573	IPP_HUMAN	Actin-binding protein IPP	10072760	Isolation and characterization of IPP, a novel human gene encoding an actin-binding, kelch-like protein.

Q99527	GPER_HUMAN	G-protein coupled estrogen receptor 1	15539556	Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells.

P31414	AVP1_ARATH	Pyrophosphate-energized vacuolar membrane proton pump 1	11572991	Drought- and salt-tolerant plants result from overexpression of the AVP1 H(+)-pump.

P50942	INP52_YEAST	Inositol-1,4,5-trisphosphate 5-phosphatase 2	15798181	The phosphoinositide phosphatase Sjl2 is recruited to cortical actin patches in the control of vesicle formation and fission during endocytosis.

P38710	INM1_YEAST	Inositol monophosphatase 1	10096091	The yeast inositol monophosphatase is a lithium- and sodium-sensitive enzyme encoded by a non-essential gene pair.

Q21227	APR1_CAEEL	Adenomatous polyposis coli protein-related protein 1	9288750	Wnt signaling and an APC-related gene specify endoderm in early C. elegans embryos.

Q9NS68	TNR19_HUMAN	Tumor necrosis factor receptor superfamily member 19	10809768	TAJ, a novel member of the tumor necrosis factor receptor family, activates the c-Jun N-terminal kinase pathway and mediates caspase- independent cell death.

Q9QZN3	FBX8_MOUSE	F-box only protein 8	10531037	A family of mammalian F-box proteins.

P51651	GPR6_RAT	G-protein coupled receptor 6	11169503	Temporally and spatially regulated expression of a candidate G- protein-coupled receptor during cerebral cortical development.

Q15392	DHC24_HUMAN	24-dehydrocholesterol reductase	11519011	Mutations in the 3beta-hydroxysterol delta24-reductase gene cause desmosterolosis, an autosomal recessive disorder of cholesterol biosynthesis.

Q9BPV8	P2Y13_HUMAN	P2Y purinoceptor 13	11546776	Identification of a novel human ADP receptor coupled to Gi.

P25701	ACP2_ARATH	Acyl carrier protein 2, chloroplastic	16668615	Expression of constitutive and tissue-specific acyl carrier protein isoforms in Arabidopsis.

P86093	BRKRN_RANNV	Ranakinin-N	17994619	A novel bradykinin-like peptide from skin secretions of the frog, Rana nigrovittata.

Q07381	TSR1_YEAST	Ribosome biogenesis protein TSR1	11565749	Bms1p, a novel GTP-binding protein, and the related Tsr1p are required for distinct steps of 40S ribosome biogenesis in yeast.

P53045	ERG25_YEAST	C-4 methylsterol oxidase	12119386	Protein-protein interactions among C-4 demethylation enzymes involved in yeast sterol biosynthesis.

P21145	MAL_HUMAN	Myelin and lymphocyte protein	3494249	cDNA cloning and sequence of MAL, a hydrophobic protein associated with human T-cell differentiation.

Q13620	CUL4B_HUMAN	Cullin-4B	8681378	cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family.

P04637	P53_HUMAN	Cellular tumor antigen p53	16415881	Structural basis for the methylation site specificity of SET7/9.

Q12233	ATPN_YEAST	ATP synthase subunit g, mitochondrial	17761666	Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase.

P47902	CDX1_HUMAN	Homeobox protein CDX-1	8530027	Isolation, characterization, and precise physical localization of human CDX1, a caudal-type homeobox gene.

P23572	CDK1_DROME	Cell division protein kinase 1	2120045	Drosophila cdc2 homologs: a functional homolog is coexpressed with a cognate variant.

Q06629	HDA2_YEAST	HDA1 complex subunit 2	14562095	Global analysis of protein localization in budding yeast.

Q9NSE2	CISH_HUMAN	Cytokine-inducible SH2-containing protein	10902923	Cloning and characterization of CIS 1b (cytokine inducible SH2- containing protein 1b), an alternative splicing form of CIS 1 gene.

Q8NCM8	DYHC2_HUMAN	Cytoplasmic dynein 2 heavy chain 1	8666668	Mammalian cells express three distinct dynein heavy chains that are localized to different cytoplasmic organelles.

Q8LGF7	UBC21_ARATH	Probable ubiquitin-conjugating enzyme E2 21	16272432	Identification and functional characterization of Arabidopsis PEROXIN4 and the interacting protein PEROXIN22.

P01612	KV120_HUMAN	Ig kappa chain V-I region Mev	6816713	Primary structure of the variable part of an amyloidogenic Bence- Jones protein (Mev). An unusual insertion in the third hypervariable region of a human kappa-immunoglobulin light chain.

P21242	PSA3_YEAST	Proteasome component C1	9087403	Structure of 20S proteasome from yeast at 2.4-A resolution.

Q96IZ0	PAWR_HUMAN	PRKC apoptosis WT1 regulator protein	11755531	p62 forms a ternary complex with PKCzeta and PAR-4 and antagonizes PAR-4-induced PKCzeta inhibition.

P0AGD1	SODC_ECOLI	Superoxide dismutase [Cu-Zn]	7929223	Escherichia coli expresses a copper- and zinc-containing superoxide dismutase.

P33416	HSP78_YEAST	Heat shock protein 78, mitochondrial	7628444	Hsp78, a Clp homologue within mitochondria, can substitute for chaperone functions of mt-hsp70.

Q9GZV5	WWTR1_HUMAN	WW domain-containing transcription regulator protein 1	11118213	TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins.

Q96RL1	UIMC1_HUMAN	BRCA1-A complex subunit RAP80	19261749	NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control.

Q9PVX8	STA31_XENLA	Signal transducer and activator of transcription 3.1	18710660	Hairy2 functions through both DNA-binding and non DNA-binding mechanisms at the neural plate border in Xenopus.

P40019	CHZ1_YEAST	Histone H2A.Z-specific chaperone CHZ1	17289584	Chz1, a nuclear chaperone for histone H2AZ.

O15446	RPA34_HUMAN	DNA-directed RNA polymerase I subunit RPA34	9426281	ASE-1: a novel protein of the fibrillar centres of the nucleolus and nucleolus organizer region of mitotic chromosomes.

Q9SEX2	KTNA1_ARATH	Katanin p60 ATPase-containing subunit	11169190	BOTERO1 is required for normal orientation of cortical microtubules and anisotropic cell expansion in Arabidopsis.

P37231	PPARG_HUMAN	Peroxisome proliferator-activated receptor gamma	10622252	Dominant negative mutations in human PPAR-gamma associated with severe insulin resistance, diabetes mellitus and hypertension.

Q13564	ULA1_HUMAN	NEDD8-activating enzyme E1 regulatory subunit	8626687	APP-BP1, a novel protein that binds to the carboxyl-terminal region of the amyloid precursor protein.

P01622	KV304_HUMAN	Ig kappa chain V-III region Ti	5027703	Rule of antibody structure. The primary structure of a monoclonal immunoglobulin L-chain of kappa-type, subgroup 3 (Bence-Jones protein Ti). IV. The complete amino acid sequence and its significance for the mechanism of antibody production.

Q9VGP2	NINAG_DROME	Neither inactivation nor afterpotential protein G	16464863	The role of Drosophila ninaG oxidoreductase in visual pigment chromophore biogenesis.

P62324	BTG1_HUMAN	Protein BTG1	1373383	BTG1, a member of a new family of antiproliferative genes.

P0ABU5	ELBB_ECOLI	Enhancing lycopene biosynthesis protein 2	9603997	Identification of genes affecting lycopene formation in Escherichia coli transformed with carotenoid biosynthetic genes: candidates for early genes in isoprenoid biosynthesis.

Q55G81	ERCC2_DICDI	TFIIH basal transcription factor complex helicase repD subunit	9649625	Rapid changes of nucleotide excision repair gene expression following UV-irradiation and cisplatin treatment of Dictyostelium discoideum.

Q9Z1K6	ARI2_MOUSE	E3 ubiquitin-protein ligase ARIH2	10431818	A family of structurally related RING finger proteins interacts specifically with the ubiquitin-conjugating enzyme UbcM4.

O14291	YF15_SCHPO	Uncharacterized protein C9E9.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q03181	PPARD_HUMAN	Peroxisome proliferator-activated receptor delta	1333051	Identification of a new member of the steroid hormone receptor superfamily that is activated by a peroxisome proliferator and fatty acids.

P52790	HXK3_HUMAN	Hexokinase-3	8717435	Purification and characterization of the carboxyl-domain of human hexokinase type III expressed as fusion protein.

Q41951	TIP21_ARATH	Aquaporin TIP2-1	15665250	Tonoplast intrinsic proteins AtTIP2;1 and AtTIP2;3 facilitate NH3 transport into the vacuole.

Q9NYM4	GPR83_HUMAN	Probable G-protein coupled receptor 83	10760605	Y-receptor-like genes GPR72 and GPR73: molecular cloning, genomic organisation and assignment to human chromosome 11q21.1 and 2p14 and mouse chromosome 9 and 6.

P38843	CHS7_YEAST	Chitin synthase export chaperone	15623581	Specialized membrane-localized chaperones prevent aggregation of polytopic proteins in the ER.

O49436	PP327_ARATH	Pentatricopeptide repeat-containing protein At4g20090	15647901	Arabidopsis emb175 and other ppr knockout mutants reveal essential roles for pentatricopeptide repeat (PPR) proteins in plant embryogenesis.

P50530	SCK1_SCHPO	Serine/threonine-protein kinase sck1	7498728	sck1, a high copy number suppressor of defects in the cAMP-dependent protein kinase pathway in fission yeast, encodes a protein homologous to the Saccharomyces cerevisiae SCH9 kinase.

O43091	DPS1_SCHPO	Decaprenyl-diphosphate synthase subunit 1	14519123	Fission yeast decaprenyl diphosphate synthase consists of Dps1 and the newly characterized Dlp1 protein in a novel heterotetrameric structure.

O23249	CKS1_ARATH	Cyclin-dependent kinases regulatory subunit 1	11319029	CKS1At overexpression in Arabidopsis thaliana inhibits growth by reducing meristem size and inhibiting cell-cycle progression.

Q01780	EXOSX_HUMAN	Exosome component 10	1383382	Cloning and characterization of the cDNA coding for a polymyositis- scleroderma overlap syndrome-related nucleolar 100-kD protein.

O13722	TAF12_SCHPO	Transcription initiation factor TFIID subunit 12	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O15165	CR001_HUMAN	Uncharacterized protein C18orf1	9479497	Multiple transcriptional variants and RNA editing in C18orf1, a novel gene with LDLRA and transmembrane domains on 18p11.2.

Q8VHI5	VITRN_MOUSE	Vitrin	18757743	Transcriptome-based systematic identification of extracellular matrix proteins.

Q9VG55	HUGIN_DROME	Protein hugin	12171930	Peptidomics of the larval Drosophila melanogaster central nervous system.

Q16281	CNGA3_HUMAN	Cyclic nucleotide-gated cation channel alpha-3	9517456	Cloning, chromosomal localization and functional expression of the gene encoding the alpha-subunit of the cGMP-gated channel in human cone photoreceptors.

Q9NY30	BTG4_HUMAN	Protein BTG4	10995567	Cloning of PC3B, a novel member of the PC3/BTG/TOB family of growth inhibitory genes, highly expressed in the olfactory epithelium.

O60160	YHYC_SCHPO	Uncharacterized mannosyltransferase C19C7.12c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q15906	VPS72_HUMAN	Vacuolar protein sorting-associated protein 72 homolog	14966270	Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans.

Q8WVK2	SNR27_HUMAN	U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein	7931148	Altered expression of the novel cellular gene as a consequence of integration of human T cell lymphotropic virus type 1.

O13710	SMC5_SCHPO	Structural maintenance of chromosomes protein 5	10747036	A novel SMC protein complex in Schizosaccharomyces pombe contains the Rad18 DNA repair protein.

Q39218	SAT3_ARATH	Serine acetyltransferase 3, mitochondrial	9830017	Isoform-dependent differences in feedback regulation and subcellular localization of serine acetyltransferase involved in cysteine biosynthesis from Arabidopsis thaliana.

Q05024	TRI1_YEAST	Protein TRI1	14562095	Global analysis of protein localization in budding yeast.

Q16385	SSX2_HUMAN	Protein SSX2	12007189	The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP.

P08235	MCR_HUMAN	Mineralocorticoid receptor	11518808	A new human MR splice variant is a ligand-independent transactivator modulating corticosteroid action.

Q9QZK7	DOK3_MOUSE	Docking protein 3	10567556	Characterization of a novel member of the DOK family that binds and modulates Abl signaling.

Q12972	PP1R8_HUMAN	Nuclear inhibitor of protein phosphatase 1	11739654	Dynamic targeting of protein phosphatase 1 within the nuclei of living mammalian cells.

P32480	HIR2_YEAST	Protein HIR2	16264190	The HIR corepressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF.

P64606	MLAE_ECOLI	Probable phospholipid ABC transporter permease protein mlaE	19383799	An ABC transport system that maintains lipid asymmetry in the gram- negative outer membrane.

Q9ZQC5	ICR2_ARATH	Interactor of constitutive active ROPs 2, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q5AZ53	MANC_EMENI	Mannan endo-1,4-beta-mannosidase C	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

P0A9X9	CSPA_ECOLI	Cold shock protein cspA	1961761	Identification of a cold shock transcriptional enhancer of the Escherichia coli gene encoding nucleoid protein H-NS.

P38225	FAT1_YEAST	Very long-chain fatty acid transport protein	9079682	Disruption of the Saccharomyces cerevisiae homologue to the murine fatty acid transport protein impairs uptake and growth on long-chain fatty acids.

Q9UI17	M2GD_HUMAN	Dimethylglycine dehydrogenase, mitochondrial	10767172	Structure and analysis of the human dimethylglycine dehydrogenase gene.

O88846	RNF4_RAT	E3 ubiquitin ligase RNF4	14987998	Transcriptional coregulator SNURF (RNF4) possesses ubiquitin E3 ligase activity.

P20340	RAB6A_HUMAN	Ras-related protein Rab-6A	19141279	Structural basis for recruitment of Rab6-interacting protein 1 to Golgi via a RUN domain.

O94813	SLIT2_HUMAN	Slit homolog 2 protein	10102268	Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance.

O88983	STX8_MOUSE	Syntaxin-8	18821010	Interaction between syntaxin 8 and HECTd3, a HECT domain ligase.

Q13351	KLF1_HUMAN	Krueppel-like factor 1	8924208	Isolation, genomic structure, and expression of human erythroid Kruppel-like factor (EKLF).

P11171	41_HUMAN	Protein 4.1	10692436	Ca(2+)-dependent and Ca(2+)-independent calmodulin binding sites in erythrocyte protein 4.1. Implications for regulation of protein 4.1 interactions with transmembrane proteins.

Q91VB2	KCC1G_MOUSE	Calcium/calmodulin-dependent protein kinase type 1G	12637513	Molecular cloning and characterization of CLICK-III/CaMKIgamma, a novel membrane-anchored neuronal Ca2+/calmodulin-dependent protein kinase (CaMK).

P32323	AGA1_YEAST	A-agglutinin anchorage subunit	7957044	Mating type-specific cell-cell recognition of Saccharomyces cerevisiae: cell wall attachment and active sites of a- and alpha- agglutinin.

Q24174	ABRU_DROME	Protein abrupt	7498790	The Drosophila abrupt gene encodes a BTB-zinc finger regulatory protein that controls the specificity of neuromuscular connections.

Q9ZU90	SKI28_ARATH	F-box protein SKIP28	12795696	Protein interaction analysis of SCF ubiquitin E3 ligase subunits from Arabidopsis.

Q05776	UPS1_YEAST	Protein UPS1	16754953	Ups1p, a conserved intermembrane space protein, regulates mitochondrial shape and alternative topogenesis of Mgm1p.

Q8LST2	WNK7_ARATH	Probable serine/threonine-protein kinase WNK7	12506983	Compilation and characterization of a novel WNK family of protein kinases in Arabiodpsis thaliana with reference to circadian rhythms.

Q03770	SSY1_YEAST	SPS-sensor component SSY1	10409731	Ssy1p and Ptr3p are plasma membrane components of a yeast system that senses extracellular amino acids.

P08842	STS_HUMAN	Steryl-sulfatase	2668275	Cloning and expression of human steroid-sulfatase. Membrane topology, glycosylation, and subcellular distribution in BHK-21 cells.

Q9C0W4	YG1J_SCHPO	Uncharacterized protein C83.19c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q99685	MGLL_HUMAN	Monoglyceride lipase	9495531	A novel poxvirus gene and its human homolog are similar to an E. coli lysophospholipase.

P61086	UBE2K_HUMAN	Ubiquitin-conjugating enzyme E2 K	17873885	E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages.

Q15700	DLG2_HUMAN	Disks large homolog 2	8755482	Heteromultimerization and NMDA receptor-clustering activity of Chapsyn-110, a member of the PSD-95 family of proteins.

P83188	PS1_PSEPD	Pseudin-1	11689009	Pseudin-2: an antimicrobial peptide with low hemolytic activity from the skin of the paradoxical frog.

Q7T019	DZIP1_DANRE	Zinc finger protein Dzip1	15198976	Iguana encodes a novel zinc-finger protein with coiled-coil domains essential for Hedgehog signal transduction in the zebrafish embryo.

Q8VI04	ASGL1_RAT	L-asparaginase	12753071	Gliap -- a novel untypical L-asparaginase localized to rat brain astrocytes.

Q9UGP4	LIMD1_HUMAN	LIM domain-containing protein 1	10647888	A novel gene containing LIM domains (LIMD1) is located within the common eliminated region 1 (C3CER1) in 3p21.3.

Q8BGG0	ZNT8_MOUSE	Zinc transporter 8	19095428	Diabetes-linked zinc transporter ZnT8 is a homodimeric protein expressed by distinct rodent endocrine cell types in the pancreas and other glands.

Q924P3	LCN8_MOUSE	Epididymal-specific lipocalin-8	11181548	Gene duplication gives rise to a new 17-kilodalton lipocalin that shows epididymal region-specific expression and testicular factor(s) regulation.

O23404	PPDK1_ARATH	Pyruvate, phosphate dikinase 1, chloroplastic	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

P20292	AL5AP_HUMAN	Arachidonate 5-lipoxygenase-activating protein	17600184	Crystal structure of inhibitor-bound human 5-lipoxygenase-activating protein.

Q9WV54	ASAH1_MOUSE	Acid ceramidase	9653654	Cloning and characterization of the full-length cDNA and genomic sequences encoding murine acid ceramidase.

Q62878	3BHS4_RAT	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 4	7690038	Structure and tissue-specific expression of a novel member of the rat 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase (3 beta- HSD) family. The exclusive 3 beta-HSD gene expression in the skin.

Q15075	EEA1_HUMAN	Early endosome antigen 1	7768953	EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine 'fingers' and contains a calmodulin-binding IQ motif.

P25092	GUC2C_HUMAN	Heat-stable enterotoxin receptor	11950846	A novel PDZ protein regulates the activity of guanylyl cyclase C, the heat-stable enterotoxin receptor.

Q07794	RT109_YEAST	Histone acetyltransferase RTT109	17272723	Rtt109 acetylates histone H3 lysine 56 and functions in DNA replication.

Q91W27	TIP39_MOUSE	Tuberoinfundibular peptide of 39 residues	11818570	Anatomical and physiological evidence for involvement of tuberoinfundibular peptide of 39 residues in nociception.

P17260	KRE1_YEAST	Protein KRE1	11853673	Kre1p, the plasma membrane receptor for the yeast K1 viral toxin.

O74358	APC13_SCHPO	Anaphase-promoting complex subunit 13	12477395	Proteomics analysis identifies new components of the fission and budding yeast anaphase-promoting complexes.

Q8CFG6	CA2D2_RAT	Voltage-dependent calcium channel subunit alpha-2/delta-2	12606261	Molecular cloning of calcium channel alpha(2)delta-subunits from rat atria and the differential regulation of their expression by IGF-1.

O15205	UBD_HUMAN	Ubiquitin D	19959714	The ubiquitin-like protein FAT10 mediates NF-kappa-B activation.

Q62231	SIX1_MOUSE	Homeobox protein SIX1	12783782	Six1 is required for the early organogenesis of mammalian kidney.

Q8K1E6	ALKB3_MOUSE	Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3	16174769	Repair of methylation damage in DNA and RNA by mammalian AlkB homologues.

Q24185	HOOK_DROME	Protein hook	8682859	Mutations in the Drosophila hook gene inhibit endocytosis of the boss transmembrane ligand into multivesicular bodies.

Q9S7E4	FDH_ARATH	Formate dehydrogenase, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P58137	ACOT8_MOUSE	Acyl-coenzyme A thioesterase 8	11673457	Characterization of an acyl-CoA thioesterase that functions as a major regulator of peroxisomal lipid metabolism.

P20772	PUR2_SCHPO	Bifunctional purine biosynthetic protein ADE1	3502942	Sequence of the bifunctional ade1 gene in the purine biosynthetic pathway of the fission yeast Schizosaccharomyces pombe.

P32602	SEC17_YEAST	Alpha-soluble NSF attachment protein	8670830	Homotypic vacuole fusion requires Sec17p (yeast alpha-SNAP) and Sec18p (yeast NSF).

O95936	EOMES_HUMAN	Eomesodermin homolog	17353897	Homozygous silencing of T-box transcription factor EOMES leads to microcephaly with polymicrogyria and corpus callosum agenesis.

Q96HA7	IKBL2_HUMAN	NF-kappa-B inhibitor-like protein 2	7738005	Cloning of a differentially expressed I kappa B-related protein.

O80448	PDX11_ARATH	Pyridoxal biosynthesis protein PDX1.1	16157873	Vitamin B6 biosynthesis in higher plants.

P20052	PHO80_YEAST	PHO85 cyclin PHO80	8108735	Phosphorylation of the transcription factor PHO4 by a cyclin-CDK complex, PHO80-PHO85.

O43173	SIA8C_HUMAN	Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase	10766765	Differential biosynthesis of polysialic acid on neural cell adhesion molecule (NCAM) and oligosaccharide acceptors by three distinct alpha2,8-Sialyltransferases, ST8Sia IV (PST), ST8Sia II (STX), and ST8Sia III.

P07271	PIF1_YEAST	DNA repair and recombination protein PIF1	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P23394	PRP28_YEAST	Pre-mRNA-splicing ATP-dependent RNA helicase PRP28	11720284	Biochemical and genetic analyses of the U5, U6, and U4/U6 x U5 small nuclear ribonucleoproteins from Saccharomyces cerevisiae.

Q810B3	BSH_MOUSE	Brain-specific homeobox protein homolog	17485440	A brain-specific homeobox gene, bsx, is essential for proper postnatal growth and nursing.

P19382	SNAI1_XENLA	Protein snail homolog Sna	12490555	Snail precedes slug in the genetic cascade required for the specification and migration of the Xenopus neural crest.

Q54UL8	MPS1_DICDI	Probable serine/threonine-protein kinase mps1	15548420	Molecular and functional analysis of the dictyostelium centrosome.

Q96AC1	FERM2_HUMAN	Fermitin family homolog 2	12679033	Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation.

Q8VE91	F134B_MOUSE	Protein FAM134B	19838196	Mutations in FAM134B, encoding a newly identified Golgi protein, cause severe sensory and autonomic neuropathy.

P62750	RL23A_HUMAN	60S ribosomal protein L23a	9417910	Cloning, sequencing, gene organization, and localization of the human ribosomal protein RPL23A gene.

Q8UVJ6	VANG2_DANRE	Vang-like protein 2	9007230	Mutations affecting cell fates and cellular rearrangements during gastrulation in zebrafish.

O95258	UCP5_HUMAN	Brain mitochondrial carrier protein 1	9852133	BMCP1, a novel mitochondrial carrier with high expression in the central nervous system of humans and rodents, and respiration uncoupling activity in recombinant yeast.

P01605	KV113_HUMAN	Ig kappa chain V-I region Lay	824717	Complete amino acid sequence of the variable domains of two human IgM anti-gamma globulins (Lay/Pom) with shared idiotypic specificities.

Q969G3	SMCE1_HUMAN	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1	16051670	hZimp7, a novel PIAS-like protein, enhances androgen receptor- mediated transcription and interacts with SWI/SNF-like BAF complexes.

Q7Z7K6	CENPV_HUMAN	Centromere protein V	12196509	Proteomic analysis of the mammalian nuclear pore complex.

P29349	CSW_DROME	Tyrosine-protein phosphatase corkscrew	1638629	Corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso.

P39744	NOC2_YEAST	Nucleolar complex protein 2	11371346	Maturation and intranuclear transport of pre-ribosomes requires Noc proteins.

Q13884	SNTB1_HUMAN	Beta-1-syntrophin	8183929	Cloning of human basic A1, a distinct 59-kDa dystrophin-associated protein encoded on chromosome 8q23-24.

P51521	OVO_DROME	Protein ovo	2116356	Genetic evidence that the ovo locus is involved in Drosophila germ line sex determination.

Q8T1G4	LYSA_DICDI	Lysozyme A	15640146	A Dictyostelium mutant with reduced lysozyme levels compensates by increased phagocytic activity.

Q09472	EP300_HUMAN	Histone acetyltransferase p300	11349124	A novel zinc finger protein TReP-132 interacts with CBP/p300 to regulate human CYP11A1 gene expression.

Q03941	CAB5_YEAST	Dephospho-CoA kinase CAB5	14690591	Assigning function to yeast proteins by integration of technologies.

A9LNK9	CPSF_ARATH	Cleavage and polyadenylation specificity factor CPSF30	16500995	Calmodulin interacts with and regulates the RNA-binding activity of an Arabidopsis polyadenylation factor subunit.

Q9GZN2	TGIF2_HUMAN	Homeobox protein TGIF2	11006116	Amplification and overexpression of TGIF2, a novel homeobox gene of the TALE superclass, in ovarian cancer cell lines.

Q12912	LRMP_HUMAN	Lymphoid-restricted membrane protein	8021504	Jaw1, a lymphoid-restricted membrane protein localized to the endoplasmic reticulum.

P36775	LONM_YEAST	Lon protease homolog, mitochondrial	8276800	PIM1 encodes a mitochondrial ATP-dependent protease that is required for mitochondrial function in the yeast Saccharomyces cerevisiae.

Q9WV89	STXB4_MOUSE	Syntaxin-binding protein 4	10394363	Synip: a novel insulin-regulated syntaxin 4-binding protein mediating GLUT4 translocation in adipocytes.

Q9US20	YLD2_SCHPO	Uncharacterized acyltransferase C1851.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O88200	CLC11_MOUSE	C-type lectin domain family 11 member A	9705843	Isolation and characterization of a cDNA for human, mouse, and rat full-length stem cell growth factor, a new member of C-type lectin superfamily.

P83320	FAR5_PENMO	FMRFamide-like neuropeptide FLP5	11959015	Seven novel FMRFamide-like neuropeptide sequences from the eyestalk of the giant tiger prawn Penaeus monodon.

Q80W68	KIRR1_MOUSE	Kin of IRRE-like protein 1	11416156	Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN.

Q96AH0	SOSB2_HUMAN	SOSS complex subunit B2	19683501	SOSS complexes participate in the maintenance of genomic stability.

O74560	RAF2_SCHPO	Rik1-associated factor 2	16040243	Two novel proteins, dos1 and dos2, interact with rik1 to regulate heterochromatic RNA interference and histone modification.

Q9R1U9	RFNG_RAT	Beta-1,3-N-acetylglucosaminyltransferase radical fringe	11165380	Radical fringe negatively modulates Notch signaling in postmitotic neurons of the rat brain.

O42645	YF94_SCHPO	RCC1 repeat-containing protein C10F6.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O96024	B3GT4_HUMAN	Beta-1,3-galactosyltransferase 4	9582303	A family of human beta3-galactosyltransferases. Characterization of four members of a UDP-galactose:beta-N-acetyl-glucosamine/beta- nacetyl-galactosamine beta-1,3-galactosyltransferase family.

Q9Y6R1	S4A4_HUMAN	Electrogenic sodium bicarbonate cotransporter 1	9235899	Cloning and functional expression of a human kidney Na+:HCO3- cotransporter.

Q9VCU9	DCR1_DROME	Endoribonuclease Dcr-1	11498593	Argonaute2, a link between genetic and biochemical analyses of RNAi.

O70405	ULK1_MOUSE	Serine/threonine-protein kinase ULK1	9600096	Identification of mouse ULK1, a novel protein kinase structurally related to C. elegans UNC-51.

Q12965	MYO1E_HUMAN	Myosin-Ie	7932763	Cloning and mRNA expression of human unconventional myosin-IC. A homologue of amoeboid myosins-I with a single IQ motif and an SH3 domain.

P48613	TIPE_DROME	Protein tipE	7553842	Cloning and functional analysis of TipE, a novel membrane protein that enhances Drosophila para sodium channel function.

Q9BUI4	RPC3_HUMAN	DNA-directed RNA polymerase III subunit RPC3	9171375	Three human RNA polymerase III-specific subunits form a subcomplex with a selective function in specific transcription initiation.

Q4U0Y4	NPL1A_XENLA	Nucleosome assembly protein 1-like 1-A	15811954	Zygotic nucleosome assembly protein-like 1 has a specific, non-cell autonomous role in hematopoiesis.

O44326	HMP2_CAEEL	Protein humpback-2	9531567	A putative catenin-cadherin system mediates morphogenesis of the Caenorhabditis elegans embryo.

Q9FNJ8	AROD5_ARATH	Arogenate dehydratase 5, chloroplastic	19136569	Tyrosine and phenylalanine are synthesized within the plastids in Arabidopsis.

Q12972	PP1R8_HUMAN	Nuclear inhibitor of protein phosphatase 1	9153239	ARD-1 cDNA from human cells encodes a site-specific single-strand endoribonuclease that functionally resembles Escherichia coli RNase E.

Q58WW2	DCAF6_HUMAN	DDB1- and CUL4-associated factor 6	15784617	NRIP, a novel nuclear receptor interaction protein, enhances the transcriptional activity of nuclear receptors.

Q9CR51	VATG1_MOUSE	V-type proton ATPase subunit G 1	12527205	Diversity of mouse proton-translocating ATPase: presence of multiple isoforms of the C, d and G subunits.

P36224	JNM1_YEAST	Nuclear migration protein JNM1	8138567	The JNM1 gene in the yeast Saccharomyces cerevisiae is required for nuclear migration and spindle orientation during the mitotic cell cycle.

O43264	ZW10_HUMAN	Centromere/kinetochore protein zw10 homolog	15272311	Involvement of BNIP1 in apoptosis and endoplasmic reticulum membrane fusion.

Q42596	THN21_ARATH	Thionin-2.1	9144959	Overexpression of an endogenous thionin enhances resistance of Arabidopsis against Fusarium oxysporum.

Q12749	SMC6_YEAST	Structural maintenance of chromosomes protein 6	15738391	A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization.

P35202	THI80_YEAST	Thiamine pyrophosphokinase	8394343	Isolation and characterization of a thiamin pyrophosphokinase gene, THI80, from Saccharomyces cerevisiae.

Q29983	MICA_HUMAN	MHC class I polypeptide-related sequence A	8901601	Cell stress-regulated human major histocompatibility complex class I gene expressed in gastrointestinal epithelium.

O13710	SMC5_SCHPO	Structural maintenance of chromosomes protein 5	12897162	Replication checkpoint kinase Cds1 regulates recombinational repair protein Rad60.

Q95017	UBC9_CAEEL	SUMO-conjugating enzyme UBC9	15990876	Chromatin regulation and sumoylation in the inhibition of Ras-induced vulval development in Caenorhabditis elegans.

Q8R003	MBNL3_MOUSE	Muscleblind-like protein 3	12297108	Inhibition of muscle differentiation by the novel muscleblind-related protein CHCR.

P41000	CPS3_SCHPO	Protein cps3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UJS0	CMC2_HUMAN	Calcium-binding mitochondrial carrier protein Aralar2	10642534	Characterization of a second member of the subfamily of calcium- binding mitochondrial carriers expressed in human non-excitable tissues.

O77059	CRY1_DROME	Cryptochrome-1	18641630	Cryptochrome mediates light-dependent magnetosensitivity in Drosophila.

Q9LDI3	CIPKO_ARATH	CBL-interacting serine/threonine-protein kinase 24	14730064	Calcium sensors and their interacting protein kinases: genomics of the Arabidopsis and rice CBL-CIPK signaling networks.

O59852	INV1_SCHPO	Invertase	9535817	Isolation and characterization of an invertase and its repressor genes from Schizosaccharomyces pombe.

P12797	BRK_MEGFL	Megascoliakinin	3617088	Two kinins isolated from an extract of the venom reservoirs of the solitary wasp Megascolia flavifrons.

P11353	HEM6_YEAST	Coproporphyrinogen-III oxidase	3516695	Purification and properties of coproporphyrinogen oxidase from the yeast Saccharomyces cerevisiae.

P70274	SEPP1_MOUSE	Selenoprotein P	9288402	cDNA and deduced polypeptide sequence of a mouse selenoprotein P.

O74384	ERFB_SCHPO	Palmitoyltransferase erf2	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

Q9VTU1	APG12_DROME	Autophagy protein 12-like	15296714	Role and regulation of starvation-induced autophagy in the Drosophila fat body.

Q9QUR2	DCTN4_RAT	Dynactin subunit 4	10525537	Analysis of dynactin subcomplexes reveals a novel actin-related protein associated with the Arp1 minifilament pointed end.

P87108	TIM10_YEAST	Mitochondrial import inner membrane translocase subunit TIM10	9822593	Tim9p, an essential partner subunit of Tim10p for the import of mitochondrial carrier proteins.

P61020	RAB5B_HUMAN	Ras-related protein Rab-5B	10491193	Direct interaction of EEA1 with Rab5b.

P14693	SAM35_YEAST	Sorting assembly machinery 35 kDa subunit	15326197	Two novel proteins in the mitochondrial outer membrane mediate beta- barrel protein assembly.

Q01453	PMP22_HUMAN	Peripheral myelin protein 22	8275092	Dejerine-Sottas syndrome associated with point mutation in the peripheral myelin protein 22 (PMP22) gene.

P18125	CP7A1_RAT	Cholesterol 7-alpha-monooxygenase	1694852	Regulation of cholesterol 7 alpha-hydroxylase in the liver. Cloning, sequencing, and regulation of cholesterol 7 alpha-hydroxylase mRNA.

Q9LSD6	ARP2_ARATH	Actin-related protein 2	10561069	The Arabidopsis ACTIN-RELATED PROTEIN 2 (AtARP2) promoter directs expression in xylem precursor cells and pollen.

O13023	HHEX_XENLA	Hematopoietically-expressed homeobox protein hhex	10508583	An anterior signalling centre in Xenopus revealed by the homeobox gene XHex.

O15145	ARPC3_HUMAN	Actin-related protein 2/3 complex subunit 3	9230079	The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly.

P36156	GTO2_YEAST	Glutathione S-transferase omega-like 2	16936141	A peroxisomal glutathione transferase of Saccharomyces cerevisiae is functionally related to sulfur amino acid metabolism.

P06844	SPT3_YEAST	Protein SPT3	12446794	The novel SLIK histone acetyltransferase complex functions in the yeast retrograde response pathway.

O94420	YQGD_SCHPO	Probable phosphoglycerate mutase C1620.13	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NY26	S39A1_HUMAN	Zinc transporter ZIP1	10610721	Isolation and characterization of human and mouse ZIRTL, a member of the IRT1 family of transporters, mapping within the epidermal differentiation complex.

Q04477	SPC24_YEAST	Kinetochore protein SPC24	11179222	The budding yeast proteins Spc24p and Spc25p interact with Ndc80p and Nuf2p at the kinetochore and are important for kinetochore clustering and checkpoint control.

Q60780	GAS7_MOUSE	Growth arrest-specific protein 7	9736752	Gas7: a gene expressed preferentially in growth-arrested fibroblasts and terminally differentiated Purkinje neurons affects neurite formation.

Q7TT18	MCAF1_MOUSE	Activating transcription factor 7-interacting protein 1	10777215	A murine ATFa-associated factor with transcriptional repressing activity.

Q8RXD3	AIP2_ARATH	E3 ubiquitin-protein ligase AIP2	15644464	Functional analysis of the RING-type ubiquitin ligase family of Arabidopsis.

O43684	BUB3_HUMAN	Mitotic checkpoint protein BUB3	9660858	The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase.

A2AH22	AMRA1_MOUSE	Activating molecule in BECN1-regulated autophagy protein 1	17589504	Ambra1 regulates autophagy and development of the nervous system.

Q9Y6P5	SESN1_HUMAN	Sestrin-1	9926927	PA26, a novel target of the p53 tumor suppressor and member of the GADD family of DNA damage and growth arrest inducible genes.

P63241	IF5A1_HUMAN	Eukaryotic translation initiation factor 5A-1	15303967	Identification of mRNA that binds to eukaryotic initiation factor 5A by affinity co-purification and differential display.

P16658	SEN2_YEAST	tRNA-splicing endonuclease subunit SEN2	12925762	Possibility of cytoplasmic pre-tRNA splicing: the yeast tRNA splicing endonuclease mainly localizes on the mitochondria.

P05549	AP2A_HUMAN	Transcription factor AP-2-alpha	12072434	Transcription factor AP-2 interacts with the SUMO-conjugating enzyme UBC9 and is sumolated in vivo.

Q07549	SNA4_YEAST	Protein SNA4	11566881	Sorting of proteins into multivesicular bodies: ubiquitin-dependent and -independent targeting.

P40303	PSA7_YEAST	Proteasome component PRE6	11500370	Cic1, an adaptor protein specifically linking the 26S proteasome to its substrate, the SCF component Cdc4.

O13766	MDE10_SCHPO	Zinc metalloprotease mde10	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

Q14185	DOCK1_HUMAN	Dedicator of cytokinesis protein 1	9808620	Activation of Rac1 by a Crk SH3-binding protein, DOCK180.

Q10182	ERFD_SCHPO	Ras modification protein erf4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q90240	CBPD_ANAPL	Carboxypeptidase D	10506132	Characterization of the enzymatic properties of the first and second domains of metallocarboxypeptidase D.

O76039	CDKL5_HUMAN	Cyclin-dependent kinase-like 5	9721213	Identification and characterization of a novel serine-threonine kinase gene from the Xp22 region.

Q9XTG7	AKT2_CAEEL	Serine/threonine-protein kinase akt-2	18358814	Direct inhibition of the longevity-promoting factor SKN-1 by insulin- like signaling in C. elegans.

Q9UKF5	ADA29_HUMAN	Disintegrin and metalloproteinase domain-containing protein 29	10512762	Isolation of two novel metalloproteinase-disintegrin (ADAM) cDNAs that show testis-specific gene expression.

Q86UT5	NHRF4_HUMAN	Na(+)/H(+) exchange regulatory cofactor NHE-RF4	11950846	A novel PDZ protein regulates the activity of guanylyl cyclase C, the heat-stable enterotoxin receptor.

Q8IUQ4	SIAH1_HUMAN	E3 ubiquitin-protein ligase SIAH1	9403064	Characterization of human homologs of the Drosophila seven in absentia (sina) gene.

P11473	VDR_HUMAN	Vitamin D3 receptor	10866662	A new family of nuclear receptor coregulators that integrates nuclear receptor signaling through CBP.

P0AD70	AMPH_ECOLI	Penicillin-binding protein AmpH	9324260	AmpC and AmpH, proteins related to the class C beta-lactamases, bind penicillin and contribute to the normal morphology of Escherichia coli.

P36562	COBT_ECOLI	Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase	7592411	The cobalamin (coenzyme B12) biosynthetic genes of Escherichia coli.

P32790	SLA1_YEAST	Actin cytoskeleton-regulatory complex protein SLA1	11950888	Sla1p couples the yeast endocytic machinery to proteins regulating actin dynamics.

Q86VW0	SESD1_HUMAN	SEC14 domain and spectrin repeat-containing protein 1	20164195	The phospholipid-binding protein SESTD1 is a novel regulator of the transient receptor potential channels TRPC4 and TRPC5.

O60896	RAMP3_HUMAN	Receptor activity-modifying protein 3	9620797	RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor.

O88387	FGD4_RAT	FYVE, RhoGEF and PH domain-containing protein 4	9668039	Frabin, a novel FGD1-related actin filament-binding protein capable of changing cell shape and activating c-Jun N-terminal kinase.

P18124	RL7_HUMAN	60S ribosomal protein L7	8441630	Structural and functional properties of ribosomal protein L7 from humans and rodents.

Q91WZ8	DTBP1_MOUSE	Dysbindin	11316798	Dysbindin, a novel coiled-coil-containing protein that interacts with the dystrobrevins in muscle and brain.

Q9N587	ACH6_CAEEL	Acetylcholine receptor subunit alpha-type unc-63	15280391	The Caenorhabditis elegans unc-63 gene encodes a levamisole-sensitive nicotinic acetylcholine receptor alpha subunit.

Q55FT9	ABIA_DICDI	Abl interactor homolog	18261908	Abi mutants in Dictyostelium reveal specific roles for the SCAR/WAVE complex in cytokinesis.

Q14451	GRB7_HUMAN	Growth factor receptor-bound protein 7	9710451	A novel variant of human Grb7 is associated with invasive esophageal carcinoma.

Q9QZ11	EXO1_MOUSE	Exonuclease 1	14716311	Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice.

P42025	ACTY_HUMAN	Beta-centractin	7696711	Beta-centractin: characterization and distribution of a new member of the centractin family of actin-related proteins.

O13849	CBPY_SCHPO	Carboxypeptidase Y	9209031	Vacuolar protein sorting in fission yeast: cloning, biosynthesis, transport, and processing of carboxypeptidase Y from Schizosaccharomyces pombe.

Q9Y258	CCL26_HUMAN	C-C motif chemokine 26	10373330	Molecular cloning and characterization of a novel human CC chemokine, SCYA26.

Q9P7P2	HOP1_SCHPO	Meiosis-specific protein hop1	16532353	Meiotic recombination proteins localize to linear elements in Schizosaccharomyces pombe.

Q8IYW5	RN168_HUMAN	E3 ubiquitin-protein ligase RNF168	19203579	RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins.

Q93646	SNT1_CAEEL	Syntrophin-1	15318222	SNF-6 is an acetylcholine transporter interacting with the dystrophin complex in Caenorhabditis elegans.

P42582	NKX25_MOUSE	Homeobox protein Nkx-2.5	15542826	Jumonji represses atrial natriuretic factor gene expression by inhibiting transcriptional activities of cardiac transcription factors.

Q9C8N5	STOP1_ARATH	Protein SENSITIVE TO PROTON RHIZOTOXICITY 1	19321711	STOP1 regulates multiple genes that protect Arabidopsis from proton and aluminum toxicities.

O14188	RNG2_SCHPO	Ras GTPase-activating-like protein rng2	9635188	Rng2p, a protein required for cytokinesis in fission yeast, is a component of the actomyosin ring and the spindle pole body.

Q14999	CUL7_HUMAN	Cullin-7	12481031	CUL7: a DOC domain-containing cullin selectively binds Skp1.Fbx29 to form an SCF-like complex.

P63000	RAC1_HUMAN	Ras-related C3 botulinum toxin substrate 1	12612085	The TRE17 oncogene encodes a component of a novel effector pathway for Rho GTPases Cdc42 and Rac1 and stimulates actin remodeling.

Q99612	KLF6_HUMAN	Krueppel-like factor 6	9000136	Identification of Bcd, a novel proto-oncogene expressed in B-cells.

Q43125	CRY1_ARATH	Cryptochrome-1	8953250	Arabidopsis cryptochrome 1 is a soluble protein mediating blue light- dependent regulation of plant growth and development.

Q9H2K8	TAOK3_HUMAN	Serine/threonine-protein kinase TAO3	10924369	Cloning of DPK, a novel dendritic cell-derived protein kinase activating the ERK1/ERK2 and JNK/SAPK pathways.

Q9QXK2	RAD18_MOUSE	E3 ubiquitin-protein ligase RAD18	11013078	Characterization of mRAD18Sc, a mouse homolog of the yeast postreplication repair gene RAD18.

Q9JHI8	NOX4_MOUSE	NADPH oxidase 4	11098048	A new superoxide-generating oxidase in murine osteoclasts.

Q04756	HGFA_HUMAN	Hepatocyte growth factor activator	7683665	Molecular cloning and sequence analysis of the cDNA for a human serine protease reponsible for activation of hepatocyte growth factor. Structural similarity of the protease precursor to blood coagulation factor XII.

P35154	SCPA_BACSU	Segregation and condensation protein A	12065423	Cell cycle-dependent localization of two novel prokaryotic chromosome segregation and condensation proteins in Bacillus subtilis that interact with SMC protein.

P28336	NMBR_HUMAN	Neuromedin-B receptor	1655761	Two distinct bombesin receptor subtypes are expressed and functional in human lung carcinoma cells.

P36334	SPIKE_CVHOC	Spike glycoprotein	8317096	Structural and functional analysis of the surface protein of human coronavirus OC43.

Q7KZI7	MARK2_HUMAN	Serine/threonine-protein kinase MARK2	15324659	aPKC acts upstream of PAR-1b in both the establishment and maintenance of mammalian epithelial polarity.

Q08162	RRP44_YEAST	Exosome complex exonuclease DIS3	10465791	The yeast exosome and human PM-Scl are related complexes of 3'-->5' exonucleases.

O70469	DOK2_MOUSE	Docking protein 2	9697832	FRIP, a hematopoietic cell-specific rasGAP-interacting protein phosphorylated in response to cytokine stimulation.

Q9T065	1A18_ARATH	1-aminocyclopropane-1-carboxylate synthase 8	12968022	Biochemical diversity among the 1-amino-cyclopropane-1-carboxylate synthase isozymes encoded by the Arabidopsis gene family.

Q9Y217	MTMR6_HUMAN	Myotubularin-related protein 6	15831468	The phosphatidylinositol 3-phosphate phosphatase myotubularin-related protein 6 (MTMR6) is a negative regulator of the Ca2+-activated K+ channel KCa3.1.

P98081	DAB_DROME	Protein disabled	7680635	Dosage-sensitive modifiers of Drosophila abl tyrosine kinase function: prospero, a regulator of axonal outgrowth, and disabled, a novel tyrosine kinase substrate.

Q9UT84	YIP6_SCHPO	Phospholipid scramblase family protein C343.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9EST8	IKBZ_MOUSE	NF-kappa-B inhibitor zeta	11086164	MAIL, a novel nuclear I kappa B protein that potentiates LPS-induced IL-6 production.

P97587	CGRF1_RAT	Cell growth regulator with RING finger domain protein 1	8968090	Induction of cell growth regulatory genes by p53.

O94614	CHR4_SCHPO	Chitin synthase regulatory factor 4	15449309	Chr4, a Schizosaccharomyces pombe homologue of the Saccharomyces cerevisiae Chs4p/Skt5p protein, is related to septum formation and is required for the proper localization of Chs2.

P40722	SOPD_SALTY	Secreted effector protein sopD	17696999	SopD acts cooperatively with SopB during Salmonella enterica serovar Typhimurium invasion.

Q8GBB2	TRMI_THET2	tRNA (adenine-N(1)-)-methyltransferase	12682365	Cloning and characterization of tRNA (m1A58) methyltransferase (TrmI) from Thermus thermophilus HB27, a protein required for cell growth at extreme temperatures.

Q9CZR2	NALD2_MOUSE	N-acetylated-alpha-linked acidic dipeptidase 2	15086519	The cloning and characterization of a second brain enzyme with NAAG peptidase activity.

P40939	ECHA_HUMAN	Trifunctional enzyme subunit alpha, mitochondrial	8135828	Structural analysis of cDNAs for subunits of human mitochondrial fatty acid beta-oxidation trifunctional protein.

Q498K9	L14BB_XENLA	Protein LSM14 homolog B-B	19458392	Participation of Xenopus Elr-type proteins in vegetal mRNA localization during oogenesis.

Q765A7	PGAP1_RAT	GPI inositol-deacylase	14734546	Inositol deacylation of glycosylphosphatidylinositol-anchored proteins is mediated by mammalian PGAP1 and yeast Bst1p.

P53350	PLK1_HUMAN	Serine/threonine-protein kinase PLK1	16760428	Phosphorylation- and polo-box-dependent binding of Plk1 to Bub1 is required for the kinetochore localization of Plk1.

P25119	TNR1B_MOUSE	Tumor necrosis factor receptor superfamily member 1B	1645445	Molecular cloning and expression of the type 1 and type 2 murine receptors for tumor necrosis factor.

P22579	SIN3_YEAST	Transcriptional regulatory protein SIN3	16314178	Stable incorporation of sequence specific repressors Ash1 and Ume6 into the Rpd3L complex.

P40857	PHS1_YEAST	3-hydroxyacyl-CoA dehydratase PHS1	14562095	Global analysis of protein localization in budding yeast.

P37610	TAUD_ECOLI	Alpha-ketoglutarate-dependent taurine dioxygenase	8808933	Identification of sulfate starvation-regulated genes in Escherichia coli: a gene cluster involved in the utilization of taurine as a sulfur source.

Q8IZQ8	MYCD_HUMAN	Myocardin	12640126	Myocardin is a critical serum response factor cofactor in the transcriptional program regulating smooth muscle cell differentiation.

Q62814	E2F5_RAT	Transcription factor E2F5	8589754	Structural characterization and specificity of expression of E2F-5: a new member of the E2F family of transcription factors.

P51829	ADCY7_MOUSE	Adenylate cyclase type 7	7961850	Molecular cloning and characterization of the type VII isoform of mammalian adenylyl cyclase expressed widely in mouse tissues and in S49 mouse lymphoma cells.

Q39241	TRXH5_ARATH	Thioredoxin H5	17322408	Thioredoxin h5 is required for victorin sensitivity mediated by a CC- NBS-LRR gene in Arabidopsis.

Q9UGK8	SRGEF_HUMAN	Secretion-regulating guanine nucleotide exchange factor	12459492	DelGEF, a homologue of the Ran guanine nucleotide exchange factor RanGEF, binds to the exocyst component Sec5 and modulates secretion.

Q12959	DLG1_HUMAN	Disks large homolog 1	19118189	Preso, a novel PSD-95-interacting FERM and PDZ domain protein that regulates dendritic spine morphogenesis.

Q8K4D3	S36A1_MOUSE	Proton-coupled amino acid transporter 1	11959859	Functional characterization of two novel mammalian electrogenic proton-dependent amino acid cotransporters.

P82701	IM18_DROME	Immune-induced peptide 18	9736738	Differential display of peptides induced during the immune response of Drosophila: a matrix-assisted laser desorption ionization time-of- flight mass spectrometry study.

P32500	NDC1_YEAST	Nucleoporin NDC1	9864355	Saccharomyces cerevisiae Ndc1p is a shared component of nuclear pore complexes and spindle pole bodies.

Q9QUS4	HEY2_MOUSE	Hairy/enhancer-of-split related with YRPW motif protein 2	15107403	The Notch target genes Hey1 and Hey2 are required for embryonic vascular development.

P04551	CDK1_SCHPO	Cell division control protein 2	2682257	Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis.

Q5UE94	TBPL2_XENLA	TATA box-binding protein-like protein 2	17703192	TBP paralogs accommodate metazoan- and vertebrate-specific developmental gene regulation.

P17813	EGLN_HUMAN	Endoglin	1692830	Primary structure of endoglin, an RGD-containing glycoprotein of human endothelial cells.

Q54TY7	SRFA_DICDI	Serum response factor homolog A	11437439	The MADS-box gene srfA is expressed in a complex pattern under the control of alternative promoters and is essential for different aspects of Dictyostelium development.

Q07551	KAR_YEAST	NADPH-dependent alpha-keto amide reductase	15564669	Purification and characterization of alpha-keto amide reductase from Saccharomyces cerevisiae.

P52732	KIF11_HUMAN	Kinesin-like protein KIF11	8548803	Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo.

Q9ULZ1	APEL_HUMAN	Apelin	10525157	Apelin, the natural ligand of the orphan receptor APJ, is abundantly secreted in the colostrum.

Q6PV61	H2A_LITVA	Histone H2A	15606770	Antimicrobial activity of histones from hemocytes of the Pacific white shrimp.

P21802	FGFR2_HUMAN	Fibroblast growth factor receptor 2	10830168	Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity.

P48608	DIA_DROME	Protein diaphanous	10751177	Functional analysis of the Drosophila diaphanous FH protein in early embryonic development.

P13393	TBP_YEAST	TATA-box-binding protein	12138208	Molecular characterization of Saccharomyces cerevisiae TFIID.

P46109	CRKL_HUMAN	Crk-like protein	8361759	Isolation and chromosomal localization of CRKL, a human crk-like gene.

Q04049	POLH_YEAST	DNA polymerase eta	11545742	Interaction with PCNA is essential for yeast DNA polymerase eta function.

P43034	LIS1_HUMAN	Platelet-activating factor acetylhydrolase IB subunit alpha	11163258	LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome.

Q9JKA9	HCN2_RAT	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2	10488052	Thyroid hormone regulates hyperpolarization-activated cyclic nucleotide-gated channel (HCN2) mRNA in the rat heart.

P51813	BMX_HUMAN	Cytoplasmic tyrosine-protein kinase BMX	7970727	BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2.

Q06418	TYRO3_HUMAN	Tyrosine-protein kinase receptor TYRO3	8108112	Cloning of the cDNA for a novel receptor tyrosine kinase, Sky, predominantly expressed in brain.

P34216	EDE1_YEAST	EH domain-containing and endocytosis protein 1	10954428	A novel EH domain protein of Saccharomyces cerevisiae, Ede1p, involved in endocytosis.

Q08491	SKI7_YEAST	Superkiller protein 7	12769863	An NMD pathway in yeast involving accelerated deadenylation and exosome-mediated 3'-->5' degradation.

P18459	TY3H_DROME	Tyrosine 3-monooxygenase	2483109	Isolation and characterization of the gene for Drosophila tyrosine hydroxylase.

P32238	CCKAR_HUMAN	Cholecystokinin receptor type A	8343165	Molecular cloning, functional expression and chromosomal localization of the human cholecystokinin type A receptor.

Q920R6	VPP4_MOUSE	V-type proton ATPase 116 kDa subunit a isoform 4	11495928	Molecular cloning and characterization of Atp6n1b: a novel fourth murine vacuolar H+-ATPase a-subunit gene.

Q15796	SMAD2_HUMAN	Mothers against decapentaplegic homolog 2	8752209	MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma.

P54762	EPHB1_HUMAN	Ephrin type-B receptor 1	8798570	Ligand activation of ELK receptor tyrosine kinase promotes its association with Grb10 and Grb2 in vascular endothelial cells.

Q9NZT1	CALL5_HUMAN	Calmodulin-like protein 5	10777582	Identification and cloning of a new calmodulin-like protein from human epidermis.

O00482	NR5A2_HUMAN	Nuclear receptor subfamily 5 group A member 2	9786908	Cloning and characterization of a novel human hepatocyte transcription factor, hB1F, which binds and activates enhancer II of hepatitis B virus.

Q9P1W8	SIRPG_HUMAN	Signal-regulatory protein gamma	15383453	Adhesion of human T cells to antigen-presenting cells through SIRPbeta2-CD47 interaction costimulates T-cell proliferation.

P32944	SWE1_YEAST	Mitosis inhibitor protein kinase SWE1	12773812	The Saccharomyces cerevisiae bud-neck proteins Kcc4 and Gin4 have distinct but partially-overlapping cellular functions.

P32608	RTG2_YEAST	Retrograde regulation protein 2	8422683	RTG1 and RTG2: two yeast genes required for a novel path of communication from mitochondria to the nucleus.

O96923	GNRA_DICDI	Gelsolin-related protein of 125 kDa	9880334	Phototactic migration of Dictyostelium cells is linked to a new type of gelsolin-related protein.

Q8T9B6	MESD_DROME	LDLR chaperone boca	12581524	Boca, an endoplasmic reticulum protein required for wingless signaling and trafficking of LDL receptor family members in Drosophila.

P10815	CG23_SCHPO	G2/mitotic-specific cyclin cdc13	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O22040	ANP1_ARATH	Mitogen-activated protein kinase kinase kinase ANP1	12034900	An Arabidopsis mitogen-activated protein kinase kinase kinase gene family encodes essential positive regulators of cytokinesis.

O95153	RIMB1_HUMAN	Peripheral-type benzodiazepine receptor-associated protein 1	9915832	Cloning and characterization of PRAX-1. A new protein that specifically interacts with the peripheral benzodiazepine receptor.

Q76LT8	UBP48_RAT	Ubiquitin carboxyl-terminal hydrolase 48	14535949	A novel ubiquitin-specific protease, synUSP, is localized at the post-synaptic density and post-synaptic lipid raft.

P06787	CALM_YEAST	Calmodulin	3533275	Isolation of the yeast calmodulin gene: calmodulin is an essential protein.

P53838	BOR1_YEAST	Boron transporter 1	11401825	Expression and characterization of the anion transporter homologue YNL275w in Saccharomyces cerevisiae.

P22301	IL10_HUMAN	Interleukin-10	1847510	Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI.

Q9JKC9	SYNRG_RAT	Synergin gamma	10477754	Gamma-synergin: an EH domain-containing protein that interacts with gamma-adaptin.

O14792	HS3S1_HUMAN	Heparan sulfate glucosamine 3-O-sulfotransferase 1	9988767	Multiple isoforms of heparan sulfate D-glucosaminyl 3-O- sulfotransferase. Isolation, characterization, and expression of human cDNAs and identification of distinct genomic loci.

P23803	ODD_DROME	Protein odd-skipped	14597202	The odd-skipped family of zinc finger genes promotes Drosophila leg segmentation.

O00743	PPP6_HUMAN	Serine/threonine-protein phosphatase 6 catalytic subunit	18186651	Protein phosphatase 6 regulatory subunits composed of ankyrin repeat domains.

P62942	FKB1A_HUMAN	Peptidyl-prolyl cis-trans isomerase FKBP1A	1701173	The cytosolic-binding protein for the immunosuppressant FK-506 is both a ubiquitous and highly conserved peptidyl-prolyl cis-trans isomerase.

P32586	PYP2_SCHPO	Tyrosine-protein phosphatase 2	1668885	Protein phosphatases in cell division: how vital are they?

O43933	PEX1_HUMAN	Peroxisome biogenesis factor 1	9398847	Mutations in PEX1 are the most common cause of peroxisome biogenesis disorders.

Q9H5F2	CK001_HUMAN	UPF0686 protein C11orf1	10873569	Characterization of five novel human genes in the 11q13-q22 region.

O08601	MTP_MOUSE	Microsomal triglyceride transfer protein large subunit	17635917	Identification of a novel isoform of microsomal triglyceride transfer protein.

O60110	OCA3_SCHPO	TPR repeat protein oca3	12237855	Genome-wide search of Schizosaccharomyces pombe genes causing overexpression-mediated cell cycle defects.

Q9NRF9	DPOE3_HUMAN	DNA polymerase epsilon subunit 3	10801849	Identification and cloning of two histone fold motif-containing subunits of HeLa DNA polymerase epsilon.

P94102	RAD51_ARATH	DNA repair protein RAD51 homolog 1	9520262	Isolation and characterisation of the RAD51 and DMC1 homologs from Arabidopsis thaliana.

P40362	UTP18_YEAST	U3 small nucleolar RNA-associated protein 18	14562095	Global analysis of protein localization in budding yeast.

P13596	NCAM1_RAT	Neural cell adhesion molecule 1	3680385	Identification of a cDNA clone that contains the complete coding sequence for a 140-kD rat NCAM polypeptide.

Q8R4H7	NAGS_MOUSE	N-acetylglutamate synthase, mitochondrial	12049647	Identification, cloning and expression of the mouse N-acetylglutamate synthase gene.

Q9V6H2	OR49B_DROME	Odorant receptor 49b	10458908	Identification of candidate Drosophila olfactory receptors from genomic DNA sequence.

Q9VNJ5	DISP_DROME	Protein dispatched	12372301	Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched.

Q9BZJ0	CRNL1_HUMAN	Crooked neck-like protein 1	12084575	Crooked neck is a component of the human spliceosome and implicated in the splicing process.

O95391	SLU7_HUMAN	Pre-mRNA-splicing factor SLU7	10197984	Human step II splicing factor hSlu7 functions in restructuring the spliceosome between the catalytic steps of splicing.

P22804	BET1_YEAST	Protein transport protein BET1	1396561	Bos1p, a membrane protein required for ER to Golgi transport in yeast, co-purifies with the carrier vesicles and with Bet1p and the ER membrane.

P36630	CG22_SCHPO	G2/mitotic-specific cyclin cig2	7909513	A B-type cyclin negatively regulates conjugation via interacting with cell cycle 'start' genes in fission yeast.

Q12080	NOP53_YEAST	Ribosome biogenesis protein NOP53	16043506	Nop53p is required for late 60S ribosome subunit maturation and nuclear export in yeast.

Q9LJZ5	UBC19_ARATH	Ubiquitin-conjugating enzyme E2 19	12427990	Molecular characterization of plant ubiquitin-conjugating enzymes belonging to the UbcP4/E2-C/UBCx/UbcH10 gene family.

Q29980	MICB_HUMAN	MHC class I polypeptide-related sequence B	11239445	ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor.

P53140	RMD9_YEAST	Protein RMD9, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

Q9FGM0	FTSHB_ARATH	ATP-dependent zinc metalloprotease FTSH 11, chloroplastic/mitochondrial	16972866	FtsH11 protease plays a critical role in Arabidopsis thermotolerance.

Q07979	RSC58_YEAST	Chromatin structure-remodeling complex protein RSC58	10025404	Histone octamer transfer by a chromatin-remodeling complex.

Q2IBC5	CAV2_RAT	Caveolin-2	11883949	ATP dependence of the SNARE/caveolin 1 interaction in the hippocampus.

P52198	RND2_HUMAN	Rho-related GTP-binding protein RhoN	8938427	Complete genomic sequence and analysis of 117 kb of human DNA containing the gene BRCA1.

O70156	OLR1_RAT	Oxidized low-density lipoprotein receptor 1	9494115	Unique repetitive sequence and unexpected regulation of expression of rat endothelial receptor for oxidized low-density lipoprotein (LOX- 1).

Q9P7J7	ADA2_SCHPO	Transcriptional adapter 2	18199689	Distinct chromatin modulators regulate the formation of accessible and repressive chromatin at the fission yeast recombination hotspot ade6-M26.

Q9JIS5	SV2A_MOUSE	Synaptic vesicle glycoprotein 2A	10624962	SV2A and SV2B function as redundant Ca2+ regulators in neurotransmitter release.

Q03391	NMDE4_MOUSE	Glutamate [NMDA] receptor subunit epsilon-4	1385220	Cloning and expression of the epsilon 4 subunit of the NMDA receptor channel.

P10674	FAS1_DROME	Fasciclin-1	3370670	Sequence analysis and neuronal expression of fasciclin I in grasshopper and Drosophila.

Q9USR4	REC27_SCHPO	Meiotic recombination protein rec27	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

O00835	ERCC3_DICDI	TFIIH basal transcription factor complex helicase repB subunit	9765592	A mutation in repB, the dictyostelium homolog of the human xeroderma pigmentosum B gene, has increased sensitivity to UV-light but normal morphogenesis.

Q9Y2M5	KLH20_HUMAN	Kelch-like protein 20	20389280	The Cullin 3 substrate adaptor KLHL20 mediates DAPK ubiquitination to control interferon responses.

Q96BS2	TESC_HUMAN	Tescalcin	18321853	Calcineurin B homologous protein 3 promotes the biosynthetic maturation, cell surface stability, and optimal transport of the Na+/H+ exchanger NHE1 isoform.

Q9NQS7	INCE_HUMAN	Inner centromere protein	16760428	Phosphorylation- and polo-box-dependent binding of Plk1 to Bub1 is required for the kinetochore localization of Plk1.

Q9LIR6	BAM1_ARATH	Beta-amylase 1, chloroplastic	18390594	Beta-AMYLASE4, a noncatalytic protein required for starch breakdown, acts upstream of three active beta-amylases in Arabidopsis chloroplasts.

P78334	GBRE_HUMAN	Gamma-aminobutyric acid receptor subunit epsilon	9039914	Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit.

Q99321	DDP1_YEAST	Diphosphoinositol polyphosphate phosphohydrolase DDP1	14562095	Global analysis of protein localization in budding yeast.

P04191	AT2A1_RABIT	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	10551848	Transmembrane helix M6 in sarco(endo)plasmic reticulum Ca(2+)-ATPase forms a functional interaction site with phospholamban. Evidence for physical interactions at other sites.

Q9R1R4	TDRD7_RAT	Tudor domain-containing protein 7	10727952	Identification of tudor repeat associator with PCTAIRE 2 (Trap). A novel protein that interacts with the N-terminal domain of PCTAIRE 2 in rat brain.

Q8WU17	RN139_HUMAN	E3 ubiquitin-protein ligase RNF139	10500182	RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination.

O00165	HAX1_HUMAN	HCLS1-associated protein X-1	10760273	The polycystic kidney disease protein PKD2 interacts with Hax-1, a protein associated with the actin cytoskeleton.

P46675	STU2_YEAST	Protein STU2	9606209	The yeast spindle pole body component Spc72p interacts with Stu2p and is required for proper microtubule assembly.

P35831	PTN12_MOUSE	Tyrosine-protein phosphatase non-receptor type 12	7772023	Murine protein tyrosine phosphatase-PEST, a stable cytosolic protein tyrosine phosphatase.

P70041	CER1_XENLA	Cerberus	12952900	Endogenous Cerberus activity is required for anterior head specification in Xenopus.

Q06148	NEJ1_YEAST	Non-homologous end-joining protein 1	11676923	Nej1p, a cell type-specific regulator of nonhomologous end joining in yeast.

Q08460	KCMA1_MOUSE	Calcium-activated potassium channel subunit alpha-1	10517674	Molecular components of large conductance calcium-activated potassium (BK) channels in mouse pituitary corticotropes.

Q14644	RASA3_HUMAN	Ras GTPase-activating protein 3	7637787	Identification of a specific Ins(1,3,4,5)P4-binding protein as a member of the GAP1 family.

Q06409	YL422_YEAST	DOCK-like protein YLR422W	14562095	Global analysis of protein localization in budding yeast.

O88677	BTG3_RAT	Protein BTG3	10564823	Expression of rat BTG3 gene, Rbtg3, is regulated by redox changes.

P63279	UBC9_HUMAN	SUMO-conjugating enzyme UBC9	16631117	Ubc9 interacts with SOX4 and represses its transcriptional activity.

Q6PB66	LPPRC_MOUSE	Leucine-rich PPR motif-containing protein, mitochondrial	12071956	LRP130, a protein containing nine pentatricopeptide repeat motifs, interacts with a single-stranded cytosine-rich sequence of mouse hypervariable minisatellite Pc-1.

P25580	PBN1_YEAST	Protein PBN1	16418276	Pbn1p: an essential endoplasmic reticulum membrane protein required for protein processing in the endoplasmic reticulum of budding yeast.

O95633	FSTL3_HUMAN	Follistatin-related protein 3	15574124	FLRG, a new ADAM12-associated protein, modulates osteoclast differentiation.

P39943	MIG3_YEAST	Transcription corepressor MIG3	14993292	The protein kinase Snf1 is required for tolerance to the ribonucleotide reductase inhibitor hydroxyurea.

Q92373	RFA2_SCHPO	Replication factor A protein 2	8702843	Purification, gene cloning, and reconstitution of the heterotrimeric single-stranded DNA-binding protein from Schizosaccharomyces pombe.

P40452	COA1_YEAST	Cytochrome oxidase assembly protein 1	14562095	Global analysis of protein localization in budding yeast.

P22830	HEMH_HUMAN	Ferrochelatase, mitochondrial	11175906	The 2.0 A structure of human ferrochelatase, the terminal enzyme of heme biosynthesis.

P36038	CBT1_YEAST	Cytochrome b termination protein 1	14562095	Global analysis of protein localization in budding yeast.

P41695	BUB1_YEAST	Checkpoint serine/threonine-protein kinase BUB1	10837255	Complex formation between Mad1p, Bub1p and Bub3p is crucial for spindle checkpoint function.

P35367	HRH1_HUMAN	Histamine H1 receptor	8280179	Genomic cloning, heterologous expression and pharmacological characterization of a human histamine H1 receptor.

Q6PIU1	KCNV1_HUMAN	Potassium voltage-gated channel subfamily V member 1	8670833	Kv8.1, a new neuronal potassium channel subunit with specific inhibitory properties towards Shab and Shaw channels.

Q6PGB8	SMCA1_MOUSE	Probable global transcription activator SNF2L1	14609955	Isolation of human NURF: a regulator of Engrailed gene expression.

Q9UMN6	MLL4_HUMAN	Histone-lysine N-methyltransferase MLL4	10409430	MLL2: a new mammalian member of the trx/MLL family of genes.

Q9BY07	S4A5_HUMAN	Electrogenic sodium bicarbonate cotransporter 4	10978526	Cloning, characterization and chromosomal assignment of NBC4, a new member of the sodium bicarbonate cotransporter family.

Q04409	EMI2_YEAST	Putative glucokinase-2	12586695	Large-scale functional genomic analysis of sporulation and meiosis in Saccharomyces cerevisiae.

Q92349	MUG79_SCHPO	Meiotically up-regulated gene 79 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P09660	ACHE_RAT	Acetylcholine receptor subunit epsilon	1702709	Primary structure and functional expression of the alpha-, beta-, gamma-, delta- and epsilon-subunits of the acetylcholine receptor from rat muscle.

P18887	XRCC1_HUMAN	DNA repair protein XRCC1	17353262	APLF (C2orf13) is a novel human protein involved in the cellular response to chromosomal DNA strand breaks.

Q8GY55	TIF4B_ARATH	Protein TIFY 4B	16916932	PEAPOD regulates lamina size and curvature in Arabidopsis.

Q08773	ISW2_YEAST	ISWI chromatin-remodeling complex ATPase ISW2	11238381	In vivo chromatin remodeling by yeast ISWI homologs Isw1p and Isw2p.

O93803	CET1_CANAL	mRNA-capping enzyme subunit beta	9755857	Isolation and characterization of the Candida albicans gene for mRNA 5'-triphosphatase: association of mRNA 5'-triphosphatase and mRNA 5'- guanylyltransferase activities is essential for the function of mRNA 5'-capping enzyme in vivo.

Q8R4G0	NTNG1_MOUSE	Netrin-G1	11804778	Complementary expression and neurite outgrowth activity of netrin-G subfamily members.

Q04048	SYF1_YEAST	Pre-mRNA-splicing factor SYF1	11842115	Functional and physical interactions between components of the Prp19p-associated complex.

Q90660	BIR_CHICK	Inhibitor of apoptosis protein	9372964	ch-IAP1, a member of the inhibitor-of-apoptosis protein family, is a mediator of the antiapoptotic activity of the v-Rel oncoprotein.

Q9SEI0	WER_ARATH	Transcription factor WER	14627722	The bHLH genes GLABRA3 (GL3) and ENHANCER OF GLABRA3 (EGL3) specify epidermal cell fate in the Arabidopsis root.

Q8BSM5	GAB3_MOUSE	GRB2-associated-binding protein 3	11739737	Gab3, a new DOS/Gab family member, facilitates macrophage differentiation.

Q9D2Y6	FBX25_MOUSE	F-box only protein 25	16714087	FBXO25, an F-box protein homologue of atrogin-1, is not induced in atrophying muscle.

P70426	RIT1_MOUSE	GTP-binding protein Rit1	8824319	Rin, a neuron-specific and calmodulin-binding small G-protein, and Rit define a novel subfamily of ras proteins.

Q15262	PTPRK_HUMAN	Receptor-type tyrosine-protein phosphatase kappa	8663237	Association of human protein-tyrosine phosphatase kappa with members of the armadillo family.

O13789	YEOB_SCHPO	Uncharacterized beta-glucan synthesis-associated protein C17G6.11c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9P0U3	SENP1_HUMAN	Sentrin-specific protease 1	10652325	Differential regulation of sentrinized proteins by a novel sentrin- specific protease.

P79960	APJA_XENLA	Apelin receptor A	17412318	Paracrine and autocrine mechanisms of apelin signaling govern embryonic and tumor angiogenesis.

P53262	VOA1_YEAST	V0 assembly protein 1	14562095	Global analysis of protein localization in budding yeast.

P15244	CEO2_LACLA	N(5)-(carboxyethyl)ornithine synthase	2498334	N(5)-(L-1-carboxyethyl)-L-ornithine:NADP(+) oxidoreductase from Streptococcus lactis. Purification and partial characterization.

Q9UFF9	CNOT8_HUMAN	CCR4-NOT transcription complex subunit 8	10036195	The human POP2 gene: identification, sequencing, and mapping to the critical region of the 5q- syndrome.

Q9WV74	ASB1_MOUSE	Ankyrin repeat and SOCS box protein 1	11509662	Functional analysis of Asb-1 using genetic modification in mice.

P11883	AL3A1_RAT	Aldehyde dehydrogenase, dimeric NADP-preferring	2831537	Cloning and complete nucleotide sequence of a full-length cDNA encoding a catalytically functional tumor-associated aldehyde dehydrogenase.

P54861	DNM1_YEAST	Dynamin-related protein DNM1	11038182	Mdv1p is a WD repeat protein that interacts with the dynamin-related GTPase, Dnm1p, to trigger mitochondrial division.

Q24564	MERH_DROME	Moesin/ezrin/radixin homolog 2	8666669	Distinct cellular and subcellular patterns of expression imply distinct functions for the Drosophila homologues of moesin and the neurofibromatosis 2 tumor suppressor, merlin.

Q9Y4A5	TRRAP_HUMAN	Transformation/transcription domain-associated protein	14966270	Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans.

P60468	SC61B_HUMAN	Protein transport protein Sec61 subunit beta	8107851	Evolutionary conservation of components of the protein translocation complex.

P55861	MCM2_XENLA	DNA replication licensing factor mcm2	9214646	The RLF-M component of the replication licensing system forms complexes containing all six MCM/P1 polypeptides.

P40482	SEC24_YEAST	Protein transport protein SEC24	14627716	Reconstitution of coat protein complex II (COPII) vesicle formation from cargo-reconstituted proteoliposomes reveals the potential role of GTP hydrolysis by Sar1p in protein sorting.

Q5QJC9	BAG5_RAT	BAG family molecular chaperone regulator 5	15603737	BAG5 inhibits parkin and enhances dopaminergic neuron degeneration.

P37020	GEF1_YEAST	Protein GEF1	16260785	The yeast Arr4p ATPase binds the chloride transporter Gef1p when copper is available in the cytosol.

Q9LSY1	ASK8_ARATH	SKP1-like protein 8	12970487	Members of the Arabidopsis-SKP1-like gene family exhibit a variety of expression patterns and may play diverse roles in Arabidopsis.

P38146	YPT10_YEAST	GTP-binding protein YPT10	10394895	Characterization of the ORF YBR264c in Saccharomyces cerevisiae, which encodes a new yeast Ypt that is degraded by a proteasome- dependent mechanism.

P19961	AMY2B_HUMAN	Alpha-amylase 2B	2401405	Cloning and characterization of a third type of human alpha-amylase gene, AMY2B.

Q93Y06	Y5720_ARATH	Probable inactive receptor kinase At5g67200	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

O94927	HAUS5_HUMAN	HAUS augmin-like complex subunit 5	19427217	HAUS, the 8-subunit human augmin complex, regulates centrosome and spindle integrity.

Q9NTI2	AT8A2_HUMAN	Probable phospholipid-transporting ATPase IB	10551800	Changes in levels of normal ML-1 gene transcripts associated with the conversion of human nontumorigenic to tumorigenic phenotypes.

Q9NPY3	C1QR1_HUMAN	Complement component C1q receptor	11781389	Identification of human CD93 as the phagocytic C1q receptor (C1qRp) by expression cloning.

O59762	GNR1_SCHPO	Guanine nucleotide-binding protein negative regulator 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q24338	ESC_DROME	Polycomb protein esc	12408864	Histone methyltransferase activity of a Drosophila Polycomb group repressor complex.

P33887	IF2G_RABIT	Eukaryotic translation initiation factor 2 subunit 3	3745199	The NH2-terminal sequence of the alpha and gamma subunits of eukaryotic initiation factor 2 and the phosphorylation site for the heme-regulated eIF-2 alpha kinase.

P92941	CLCA_ARATH	Chloride channel protein CLC-a	8969232	A family of putative chloride channels from Arabidopsis and functional complementation of a yeast strain with a CLC gene disruption.

P18125	CP7A1_RAT	Cholesterol 7-alpha-monooxygenase	2335522	Cloning and regulation of cholesterol 7 alpha-hydroxylase, the rate- limiting enzyme in bile acid biosynthesis.

O60124	RRP42_SCHPO	Exosome complex component rrp42	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q21339	NAD3_CAEEL	Sodium-dependent high-affinity dicarboxylate transporter 3	12480943	Structural and functional characteristics of two sodium-coupled dicarboxylate transporters (ceNaDC1 and ceNaDC2) from Caenorhabditis elegans and their relevance to life span.

P34253	KTI12_YEAST	Protein KTI12	12139626	Protein interactions within Saccharomyces cerevisiae Elongator, a complex essential for Kluyveromyces lactis zymocicity.

Q8VE47	UBA5_MOUSE	Ubiquitin-like modifier-activating enzyme 5	20018847	A novel type of E3 ligase for the Ufm1 conjugation system.

Q9LZW4	CIPKE_ARATH	CBL-interacting serine/threonine-protein kinase 14	11230129	The NAF domain defines a novel protein-protein interaction module conserved in Ca(2+)-regulated kinases.

Q06708	VAC14_YEAST	Vacuole morphology and inheritance protein 14	14528018	Vacuole size control: regulation of PtdIns(3,5)P2 levels by the vacuole-associated Vac14-Fig4 complex, a PtdIns(3,5)P2-specific phosphatase.

P35916	VGFR3_HUMAN	Vascular endothelial growth factor receptor 3	8386825	The FLT4 gene encodes a transmembrane tyrosine kinase related to the vascular endothelial growth factor receptor.

P07713	DECA_DROME	Protein decapentaplegic	11231061	Regulation of pattern formation in the Drosophila hindgut by wg, hh, dpp, and en.

Q07326	PIGF_HUMAN	Phosphatidylinositol-glycan biosynthesis class F protein	15632136	GPI7 is the second partner of PIG-F and involved in modification of glycosylphosphatidylinositol.

Q9UHB6	LIMA1_HUMAN	LIM domain and actin-binding protein 1	10618726	EPLIN, epithelial protein lost in neoplasm.

P36516	RM03_YEAST	54S ribosomal protein L3, mitochondrial	12392552	Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components.

Q9XGM8	MGAT1_ARATH	Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	18768906	Comparative analyses of arabidopsis complex glycan1 mutants and genetic interaction with staurosporin and temperature sensitive3a.

P04426	WNT1_MOUSE	Proto-oncogene Wnt-1	16543246	Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression.

O94461	YFFL_SCHPO	Probable phosphoglycerate mutase C1687.21	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P54623	CNN_DROME	Centrosomin	8653793	The homeotic target gene centrosomin encodes an essential centrosomal component.

Q9FI37	PEN4_ARATH	Thalianol synthase	15125655	Genome mining to identify new plant triterpenoids.

Q03860	TVP15_YEAST	Golgi apparatus membrane protein TVP15	17178117	Tvp38, Tvp23, Tvp18 and Tvp15: novel membrane proteins in the Tlg2- containing Golgi/endosome compartments of Saccharomyces cerevisiae.

O13698	FABD_SCHPO	Malonyl CoA-acyl carrier protein transacylase, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8NHJ6	LIRB4_HUMAN	Leukocyte immunoglobulin-like receptor subfamily B member 4	9151699	A novel inhibitory receptor (ILT3) expressed on monocytes, macrophages, and dendritic cells involved in antigen processing.

Q9BXH1	BBC3_HUMAN	Bcl-2-binding component 3	11463392	PUMA, a novel proapoptotic gene, is induced by p53.

O74473	CDC11_SCHPO	Septation initiation network scaffold protein cdc11	12546793	Mitotic hyperphosphorylation of the fission yeast SIN scaffold protein cdc11p is regulated by the protein kinase cdc7p.

P15735	PHKG2_HUMAN	Phosphorylase b kinase gamma catalytic chain, testis/liver isoform	2948189	Homology probing: identification of cDNA clones encoding members of the protein-serine kinase family.

P06780	RHO1_YEAST	GTP-binding protein RHO1	8947028	Bni1p implicated in cytoskeletal control is a putative target of Rho1p small GTP binding protein in Saccharomyces cerevisiae.

P40032	TPA1_YEAST	PKHD-type hydroxylase TPA1	14562095	Global analysis of protein localization in budding yeast.

Q9Y4L5	RN115_HUMAN	E3 ubiquitin-protein ligase RNF115	18819927	Autoubiquitination of BCA2 RING E3 ligase regulates its own stability and affects cell migration.

Q9W420	SPT6H_DROME	Transcription elongation factor SPT6	12490954	The RNA processing exosome is linked to elongating RNA polymerase II in Drosophila.

Q680Q4	SIZ1_ARATH	E3 SUMO-protein ligase SIZ1	19276109	Sumoylation of ABI5 by the Arabidopsis SUMO E3 ligase SIZ1 negatively regulates abscisic acid signaling.

P43633	ALK1_YEAST	Serine/threonine-protein kinase Haspin homolog ALK1	16855400	Alk1 and Alk2 are two new cell cycle-regulated haspin-like proteins in budding yeast.

Q05543	RT103_YEAST	Regulator of Ty1 transposition protein 103	15565157	The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II.

P34969	5HT7R_HUMAN	5-hydroxytryptamine receptor 7	8226867	Cloning of a novel human serotonin receptor (5-HT7) positively linked to adenylate cyclase.

Q7Z992	SST6_SCHPO	ESCRT-I complex subunit vps23	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P87233	PHF1_SCHPO	SWM histone demethylase complex subunit phf1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9XZ08	EXT3_DROME	Exostosin-3	14998928	Distinct and collaborative roles of Drosophila EXT family proteins in morphogen signalling and gradient formation.

O74365	SOL1_SCHPO	SWI/SNF chromatin-remodeling complex subunit sol1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9W6A9	OP1S1_DANRE	Opsin-1, short-wave-sensitive 1	10349976	Cloning and characterization of six zebrafish photoreceptor opsin cDNAs and immunolocalization of their corresponding proteins.

O08678	MARK1_RAT	Serine/threonine-protein kinase MARK1	9108484	MARK - a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption.

P06104	UBC2_YEAST	Ubiquitin-conjugating enzyme E2 2	3306404	The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme.

Q8IXM6	NRM_HUMAN	Nurim	10402458	A visual screen of a GFP-fusion library identifies a new type of nuclear envelope membrane protein.

P53197	CDH1_YEAST	APC/C activator protein CDH1	12456658	Cell cycle-dependent nuclear export of Cdh1p may contribute to the inactivation of APC/C(Cdh1).

P01615	KV202_HUMAN	Ig kappa chain V-II region FR	821524	Variable region sequence of the light chain from a Waldenstroms IgM with specificity for phosphorylcholine.

Q9Z2Y3	HOME1_MOUSE	Homer protein homolog 1	9808458	Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins.

Q10103	CHP1_SCHPO	Chromo domain-containing protein 1	10835380	Four chromo-domain proteins of Schizosaccharomyces pombe differentially repress transcription at various chromosomal locations.

O60137	SWD2_SCHPO	Set1 complex component swd2	12488447	High conservation of the Set1/Rad6 axis of histone 3 lysine 4 methylation in budding and fission yeasts.

P31483	TIA1_HUMAN	Nucleolysin TIA-1 isoform p40	1934064	A polyadenylate binding protein localized to the granules of cytolytic lymphocytes induces DNA fragmentation in target cells.

P51571	SSRD_HUMAN	Translocon-associated protein subunit delta	9286695	Genomic organization of two novel genes on human Xq28: compact head to head arrangement of IDH gamma and TRAP delta is conserved in rat and mouse.

Q8MT06	GNL3_DROME	Guanine nucleotide-binding protein-like 3 homolog	18628395	A nucleostemin family GTPase, NS3, acts in serotonergic neurons to regulate insulin signaling and control body size.

Q12968	NFAC3_HUMAN	Nuclear factor of activated T-cells, cytoplasmic 3	7749981	Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins.

Q06149	PDR8_YEAST	Transcription factor PDR8	12529331	A general strategy to uncover transcription factor properties identifies a new regulator of drug resistance in yeast.

P68036	UB2L3_HUMAN	Ubiquitin-conjugating enzyme E2 L3	20061386	The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.

Q9ER42	BARX1_MOUSE	Homeobox protein BarH-like 1	17855428	Independent functions and mechanisms for homeobox gene Barx1 in patterning mouse stomach and spleen.

P01699	LV101_HUMAN	Ig lambda chain V-I region VOR	809332	Pattern of antibody structure. The amino acid sequence of a monoclonal immunoglobulin L-chain of lambde-type, subgroup I (Bence- Jones-protein Vor.). A contribution to the elucidation of the origin of antibody specificity.

P25114	F264_RAT	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4	1651918	Molecular cloning of the DNA and expression and characterization of rat testes fructose-6-phosphate,2-kinase:fructose-2,6- bisphosphatase.

P27716	INX1_DROME	Innexin inx1	1963867	Molecular cloning and analysis of l(1)ogre, a locus of Drosophila melanogaster with prominent effects on the postembryonic development of the central nervous system.

Q9UBS8	RNF14_HUMAN	E3 ubiquitin-protein ligase RNF14	11322894	N-terminally extended human ubiquitin-conjugating enzymes (E2s) mediate the ubiquitination of RING-finger proteins, ARA54 and RNF8.

Q94K01	DBR1_ARATH	Lariat debranching enzyme	14570879	An Arabidopsis RNA lariat debranching enzyme is essential for embryogenesis.

O16785	PARV_CAEEL	Paralyzed arrest at two-fold protein 6	12781130	C. elegans PAT-6/actopaxin plays a critical role in the assembly of integrin adhesion complexes in vivo.

P43255	CSN8_ARATH	COP9 signalosome complex subunit 8	12615944	Characterization of the last subunit of the Arabidopsis COP9 signalosome: implications for the overall structure and origin of the complex.

P35845	OSH1_YEAST	Oxysterol-binding protein homolog 1	11408574	Dual targeting of Osh1p, a yeast homologue of oxysterol-binding protein, to both the Golgi and the nucleus-vacuole junction.

O95470	SGPL1_HUMAN	Sphingosine-1-phosphate lyase 1	14570870	Sphingosine-phosphate lyase enhances stress-induced ceramide generation and apoptosis.

Q03188	CENPC_HUMAN	Centromere protein C 1	1339310	CENP-C, an autoantigen in scleroderma, is a component of the human inner kinetochore plate.

Q3KQ35	S17AA_XENLA	Transcription factor Sox-17-alpha-A	11091074	Changes in embryonic cell fate produced by expression of an endodermal transcription factor, Xsox17.

Q13561	DCTN2_HUMAN	Dynactin subunit 2	8647893	Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis.

Q13177	PAK2_HUMAN	Serine/threonine-protein kinase PAK 2	7744004	A novel serine kinase activated by rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20.

P60720	LIPB_ECOLI	Octanoyltransferase	12591875	The Escherichia coli lipB gene encodes lipoyl (octanoyl)-acyl carrier protein:protein transferase.

Q6RT24	CENPE_MOUSE	Centromere-associated protein E	12925705	Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss.

Q12063	UPPS_YEAST	Probable undecaprenyl pyrophosphate synthase	14690591	Assigning function to yeast proteins by integration of technologies.

Q9UBS0	KS6B2_HUMAN	Ribosomal protein S6 kinase beta-2	9804755	Molecular cloning and characterization of a novel p70 S6 kinase, p70 S6 kinase beta containing a proline-rich region.

O74184	WAT1_SCHPO	WD repeat-containing protein wat1	11686295	Conserved Wat1/Pop3 WD-repeat protein of fission yeast secures genome stability through microtubule integrity and may be involved in mRNA maturation.

Q06336	GGA1_YEAST	ADP-ribosylation factor-binding protein GGA1	10747088	A family of proteins with gamma-adaptin and VHS domains that facilitate trafficking between the trans-Golgi network and the vacuole/lysosome.

Q9LUH9	EPFL5_ARATH	EPIDERMAL PATTERNING FACTOR-like protein 5	19435754	Epidermal cell density is autoregulated via a secretory peptide, EPIDERMAL PATTERNING FACTOR 2 in Arabidopsis leaves.

P42935	ELP2_YEAST	Elongator complex protein 2	12139626	Protein interactions within Saccharomyces cerevisiae Elongator, a complex essential for Kluyveromyces lactis zymocicity.

Q9UT52	MOD21_SCHPO	Gamma-tubulin complex subunit mod21	17021256	Noncore components of the fission yeast gamma-tubulin complex.

Q16478	GRIK5_HUMAN	Glutamate receptor, ionotropic kainate 5	1321949	Molecular structure and pharmacological characterization of humEAA2, a novel human kainate receptor subunit.

Q8N1V2	WDR16_HUMAN	WD repeat-containing protein 16	15967112	WDRPUH, a novel WD-repeat-containing protein, is highly expressed in human hepatocellular carcinoma and involved in cell proliferation.

O15350	P73_HUMAN	Tumor protein p73	11706030	Differential effect of ik3-1/cables on p53- and p73-induced cell death.

Q93705	UNC3_CAEEL	Transcription factor unc-3	9502737	unc-3, a gene required for axonal guidance in Caenorhabditis elegans, encodes a member of the O/E family of transcription factors.

P40019	CHZ1_YEAST	Histone H2A.Z-specific chaperone CHZ1	14562095	Global analysis of protein localization in budding yeast.

Q02792	XRN2_YEAST	5'-3' exoribonuclease 2	9488433	Processing of the precursors to small nucleolar RNAs and rRNAs requires common components.

Q9CPV5	PMF1_MOUSE	Polyamine-modulated factor 1	11583586	Cloning and characterization of the mouse polyamine-modulated factor- 1 (mPMF-1) gene: an alternatively spliced homologue of the human transcription factor.

Q96C10	DHX58_HUMAN	Probable ATP-dependent RNA helicase DHX58	17190814	Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2.

O74690	SNU13_SCHPO	13 kDa ribonucleoprotein-associated protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q920G8	MFRN1_MOUSE	Mitoferrin-1	16511496	Mitoferrin is essential for erythroid iron assimilation.

P55861	MCM2_XENLA	DNA replication licensing factor mcm2	9851868	Evidence for different MCM subcomplexes with differential binding to chromatin in Xenopus.

Q04338	VTI1_YEAST	t-SNARE VTI1	9398683	Characterization of a novel yeast SNARE protein implicated in Golgi retrograde traffic.

Q8IWV2	CNTN4_HUMAN	Contactin-4	14571131	Cloning and characterization of the human neural cell adhesion molecule, CNTN4 (alias BIG-2).

Q13263	TIF1B_HUMAN	Transcription intermediary factor 1-beta	9016654	Transcriptional repression by RING finger protein TIF1 beta that interacts with the KRAB repressor domain of KOX1.

O00254	PAR3_HUMAN	Proteinase-activated receptor 3	9087410	Protease-activated receptor 3 is a second thrombin receptor in humans.

Q9JKL9	PR2B1_RAT	Prolactin-2B1	10471365	Identification of four members of the rat prolactin/growth hormone gene family.

Q6TL19	GUC2G_MOUSE	Guanylate cyclase 2G	14713286	Identification of an orphan guanylate cyclase receptor selectively expressed in mouse testis.

Q8IWZ6	BBS7_HUMAN	Bardet-Biedl syndrome 7 protein	17574030	A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis.

Q08204	SMC5_YEAST	Structural maintenance of chromosomes protein 5	15738391	A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization.

Q9ES19	ATF4_RAT	Cyclic AMP-dependent transcription factor ATF-4	10924501	The metabotropic GABAB receptor directly interacts with the activating transcription factor 4.

Q9NQ55	SSF1_HUMAN	Suppressor of SWI4 1 homolog	15302935	Large-scale characterization of HeLa cell nuclear phosphoproteins.

P38792	RRP4_YEAST	Exosome complex component RRP4	9390555	The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases.

O76329	ACTNB_DICDI	Interaptin	18266910	Dictyostelium Sun-1 connects the centrosome to chromatin and ensures genome stability.

Q9S7Z3	PCS1_ARATH	Glutathione gamma-glutamylcysteinyltransferase 1	16489135	A reassessment of substrate specificity and activation of phytochelatin synthases from model plants by physiologically relevant metals.

P77671	ALLB_ECOLI	Allantoinase	12486048	Metal ion dependence of recombinant Escherichia coli allantoinase.

P10275	ANDR_HUMAN	Androgen receptor	15563469	The molecular mechanisms of coactivator utilization in ligand- dependent transactivation by the androgen receptor.

Q800Q5	T7L1B_DANRE	Transcription factor 7-like 1-B	15366005	Rhombomere boundaries are Wnt signaling centers that regulate metameric patterning in the zebrafish hindbrain.

O42923	CIP1_SCHPO	RNA-binding post-transcriptional regulator cip1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P39286	RSGA_ECOLI	Putative ribosome biogenesis GTPase RsgA	12220175	YjeQ, an essential, conserved, uncharacterized protein from Escherichia coli, is an unusual GTPase with circularly permuted G- motifs and marked burst kinetics.

Q9UHE8	STEA1_HUMAN	Metalloreductase STEAP1	10588738	STEAP: a prostate-specific cell-surface antigen highly expressed in human prostate tumors.

Q90XF2	KPCI_DANRE	Protein kinase C iota type	11591316	Positional cloning of heart and soul reveals multiple roles for PKC lambda in zebrafish organogenesis.

P53076	VID30_YEAST	Vacuolar import and degradation protein 30	12686616	Catabolite degradation of fructose-1,6-bisphosphatase in the yeast Saccharomyces cerevisiae: a genome-wide screen identifies eight novel GID genes and indicates the existence of two degradation pathways.

Q29983	MICA_HUMAN	MHC class I polypeptide-related sequence A	11830641	Binding of Escherichia coli adhesin AfaE to CD55 triggers cell- surface expression of the MHC class I-related molecule MICA.

P36132	KAE1_YEAST	Putative glycoprotein endopeptidase KAE1	16564010	A genome-wide screen identifies the evolutionarily conserved KEOPS complex as a telomere regulator.

P30536	TSPOA_HUMAN	Translocator protein	16822554	Translocator protein (18kDa): new nomenclature for the peripheral- type benzodiazepine receptor based on its structure and molecular function.

O15265	ATX7_HUMAN	Ataxin-7	15115762	Ataxin-7 is a subunit of GCN5 histone acetyltransferase-containing complexes.

P57059	SIK1_HUMAN	Serine/threonine-protein kinase SIK1	16306228	14-3-3 cooperates with LKB1 to regulate the activity and localization of QSK and SIK.

P01624	KV306_HUMAN	Ig kappa chain V-III region POM	60899	The amino acid sequence of the variable regions of the light chains from two idiotypically cross reactive IgM anti-gamma globulins.

P54003	SUR7_YEAST	Protein SUR7	15536122	Distribution of Can1p into stable domains reflects lateral protein segregation within the plasma membrane of living S. cerevisiae cells.

P25369	LSB5_YEAST	LAS seventeen-binding protein 5	12388763	Novel proteins linking the actin cytoskeleton to the endocytic machinery in Saccharomyces cerevisiae.

Q61083	M3K2_MOUSE	Mitogen-activated protein kinase kinase kinase 2	12912994	PB1 domains of MEKK2 and MEKK3 interact with the MEK5 PB1 domain for activation of the ERK5 pathway.

P40899	ISP3_SCHPO	Sexual differentiation process protein isp3	7954893	Identification and characterization of genes induced during sexual differentiation in Schizosaccharomyces pombe.

O73622	PAT_XENLA	Protein Pat	15744663	Delivery of germinal granules and localized RNAs via the messenger transport organizer pathway to the vegetal cortex of Xenopus oocytes occurs through directional expansion of the mitochondrial cloud.

Q8R409	HEXI1_MOUSE	Protein HEXIM1	12119119	Structure, expression, and functional characterization of the mouse CLP-1 gene.

Q03940	RUVB1_YEAST	RuvB-like protein 1	14690608	A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1.

P48050	IRK4_HUMAN	Inward rectifier potassium channel 4	8051145	Cloning and expression of a novel human brain inward rectifier potassium channel.

Q95RV2	CAV_DROME	Telomere-binding protein cav	19181850	The Drosophila modigliani (moi) gene encodes a HOAP-interacting protein required for telomere protection.

P00352	AL1A1_HUMAN	Retinal dehydrogenase 1	2987944	Cloning of cDNAs for human aldehyde dehydrogenases 1 and 2.

P63012	RAB3A_RAT	Ras-related protein Rab-3A	7532276	Interaction cloning of Rabin3, a novel protein that associates with the Ras-like GTPase Rab3A.

Q9Y7Z6	YP02_SCHPO	Meiotic chromosome segregation protein C1539.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q6P9B9	INT5_HUMAN	Integrator complex subunit 5	16239144	Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.

Q9VTY6	UBE2C_DROME	Ubiquitin-conjugating enzyme E2 C	19822757	Identification of a physiological E2 module for the human anaphase- promoting complex.

P40473	POG1_YEAST	Transcriptional acticator POG1	9927449	POG1, a novel yeast gene, promotes recovery from pheromone arrest via the G1 cyclin CLN2.

O94520	YQ13_SCHPO	Uncharacterized membrane protein C1281.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q6Q4D0	BRU1_ARATH	Protein BRUSHY 1	14966212	MGOUN3, an Arabidopsis gene with tetratricopeptide-repeat-related motifs, regulates meristem cellular organization.

P46964	OST2_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2	7593165	The essential OST2 gene encodes the 16-kD subunit of the yeast oligosaccharyltransferase, a highly conserved protein expressed in diverse eukaryotic organisms.

Q9ER88	RT29_MOUSE	28S ribosomal protein S29, mitochondrial	11017876	The apoptosis mediator mDAP-3 is a novel member of a conserved family of mitochondrial proteins.

Q9NR96	TLR9_HUMAN	Toll-like receptor 9	11130078	A Toll-like receptor recognizes bacterial DNA.

Q8UVX0	PIWL1_DANRE	Piwi-like protein 1	17418787	A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in Zebrafish.

Q60838	DVL2_MOUSE	Segment polarity protein dishevelled homolog DVL-2	15456783	Independent mutations in mouse Vangl2 that cause neural tube defects in looptail mice impair interaction with members of the Dishevelled family.

O43290	SNUT1_HUMAN	U4/U6.U5 tri-snRNP-associated protein 1	9856836	Molecular characterization of an autoallergen, Hom s 1, identified by serum IgE from atopic dermatitis patients.

Q9LD43	ACCA_ARATH	Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, chloroplastic	12938931	Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis.

Q9H160	ING2_HUMAN	Inhibitor of growth protein 2	10072587	Cloning of a novel gene (ING1L) homologous to ING1, a candidate tumor suppressor.

P11712	CP2C9_HUMAN	Cytochrome P450 2C9	3032244	Cloning and sequence determination of a complementary DNA related to human liver microsomal cytochrome P-450 S-mephenytoin 4-hydroxylase.

P58960	GR39B_DROME	Putative gustatory receptor 39b	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

O59821	CSL4_SCHPO	Exosome complex component csl4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O76082	S22A5_HUMAN	Solute carrier family 22 member 5	9618255	cDNA sequence, transport function, and genomic organization of human OCTN2, a new member of the organic cation transporter family.

Q03880	PKR1_YEAST	V-type ATPase assembly factor PKR1	16926153	PKR1 encodes an assembly factor for the yeast V-type ATPase.

P53835	PRM1_YEAST	Plasma membrane fusion protein PRM1	11062271	Prm1p, a pheromone-regulated multispanning membrane protein, facilitates plasma membrane fusion during yeast mating.

P25656	CDC50_YEAST	Cell division control protein 50	12589066	Cdc50p, a conserved endosomal membrane protein, controls polarized growth in Saccharomyces cerevisiae.

P96614	CSHA_BACSU	DEAD-box ATP-dependent RNA helicase cshA	16352840	Cold-induced putative DEAD box RNA helicases CshA and CshB are essential for cold adaptation and interact with cold shock protein B in Bacillus subtilis.

O13370	DED1_SCHPO	ATP-dependent RNA helicase ded1	16273369	Moc3, a novel Zn finger type protein involved in sexual development, ascus formation, and stress response of Schizosaccharomyces pombe.

P82538	PPL1_ARATH	PsbP-like protein 1, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q13363	CTBP1_HUMAN	C-terminal-binding protein 1	11568182	Interaction of EVI1 with cAMP-responsive element-binding protein- binding protein (CBP) and p300/CBP-associated factor (P/CAF) results in reversible acetylation of EVI1 and in co-localization in nuclear speckles.

Q94JY4	BRK1_ARATH	Protein BRICK 1	15534215	Activation of Arp2/3 complex-dependent actin polymerization by plant proteins distantly related to Scar/WAVE.

P34903	GBRA3_HUMAN	Gamma-aminobutyric acid receptor subunit alpha-3	8391122	Cloning of cDNA sequences encoding human alpha 2 and alpha 3 gamma- aminobutyric acidA receptor subunits and characterization of the benzodiazepine pharmacology of recombinant alpha 1-, alpha 2-, alpha 3-, and alpha 5-containing human gamma-aminobutyric acidA receptors.

Q9D1P4	CHRD1_MOUSE	Cysteine and histidine-rich domain-containing protein 1	12965203	Chp-1 and melusin, two CHORD containing proteins in vertebrates.

P32907	ATO2_YEAST	Ammonia transport outward protein 2	12429834	Ammonia pulses and metabolic oscillations guide yeast colony development.

P38572	UPK1A_BOVIN	Uroplakin-1a	12475947	Specific heterodimer formation is a prerequisite for uroplakins to exit from the endoplasmic reticulum.

P38278	YBZ1_YEAST	UPF0657 nucleolar protein YBR141C	14562095	Global analysis of protein localization in budding yeast.

P53184	PNC1_YEAST	Nicotinamidase	12736687	Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae.

Q05892	YL290_YEAST	Uncharacterized protein YLR290C, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

P60953	CDC42_HUMAN	Cell division control protein 42 homolog	10816584	SPECs, small binding proteins for Cdc42.

P00927	THDH_YEAST	Threonine dehydratase, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P27213	PTPS_RAT	6-pyruvoyl tetrahydrobiopterin synthase	1939130	Purification and cDNA cloning of rat 6-pyruvoyl-tetrahydropterin synthase.

P60761	NEUG_MOUSE	Neurogranin	11016969	Involvement of neurogranin in the modulation of calcium/calmodulin- dependent protein kinase II, synaptic plasticity, and spatial learning: a study with knockout mice.

Q8TEW0	PARD3_HUMAN	Partitioning defective 3 homolog	10934474	The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42.

Q9UKT4	FBX5_HUMAN	F-box only protein 5	15148369	Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome.

O75821	EIF3G_HUMAN	Eukaryotic translation initiation factor 3 subunit G	17322308	Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry.

P59941	SIRT6_MOUSE	NAD-dependent deacetylase sirtuin-6	15795229	Mouse Sir2 homolog SIRT6 is a nuclear ADP-ribosyltransferase.

Q9NZJ9	NUDT4_HUMAN	Diphosphoinositol polyphosphate phosphohydrolase 2	10777568	Discovery of molecular and catalytic diversity among human diphosphoinositol-polyphosphate phosphohydrolases. The expanding NUDT family.

Q8L4Y5	ARP7_ARATH	Actin-related protein 7	12609034	Cell cycle-dependent association of Arabidopsis actin-related proteins AtARP4 and AtARP7 with the nucleus.

O35054	CLD4_MOUSE	Claudin-4	9892664	Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands.

Q03213	HOT1_YEAST	High-osmolarity-induced transcription protein 1	10409737	Osmotic stress-induced gene expression in Saccharomyces cerevisiae requires Msn1p and the novel nuclear factor Hot1p.

Q92990	GLMN_HUMAN	Glomulin	11571281	Ligand-regulated binding of FAP68 to the hepatocyte growth factor receptor.

P25714	OXAA_ECOLI	Inner membrane protein oxaA	10675323	YidC, the Escherichia coli homologue of mitochondrial Oxa1p, is a component of the Sec translocase.

P47128	EAF6_YEAST	Chromatin modification-related protein EAF6	14562095	Global analysis of protein localization in budding yeast.

P83624	HBB1_PSEUR	Hemoglobin subunit beta-1	15340169	Structure and function of the Gondwanian hemoglobin of Pseudaphritis urvillii, a primitive notothenioid fish of temperate latitudes.

Q12918	KLRB1_HUMAN	Killer cell lectin-like receptor subfamily B member 1	8077657	Human NKR-P1A: a disulfide-linked homodimer of the C-type lectin superfamily expressed by a subset of NK and T lymphocytes.

Q03180	PIR3_YEAST	Cell wall mannoprotein PIR3	10407261	Role of NaOH-extractable cell wall proteins Ccw5p, Ccw6p, Ccw7p and Ccw8p (members of the Pir protein family) in stability of the Saccharomyces cerevisiae cell wall.

Q80VW5	WHRN_MOUSE	Whirlin	12124769	Elongation of hair cell stereocilia is defective in the mouse mutant whirler.

O42909	YBI2_SCHPO	Zinc-type alcohol dehydrogenase-like protein C16A3.02c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q99MK2	KAT5_RAT	Histone acetyltransferase KAT5	11441186	A transcriptionally active complex of APP with Fe65 and histone acetyltransferase Tip60.

P36169	SKG1_YEAST	Suppressor of lethality of KEX2 GAS1 double null mutant protein 1	14562095	Global analysis of protein localization in budding yeast.

P23642	VAN1_YEAST	Mannan polymerase I complex VAN1 subunit	9434768	Novel membrane protein complexes for protein glycosylation in the yeast Golgi apparatus.

P59266	FITM2_MOUSE	Fat storage-inducing transmembrane protein 2	18160536	Evolutionarily conserved gene family important for fat storage.

Q7FZF1	CNBL5_ARATH	Calcineurin B-like protein 5	11230129	The NAF domain defines a novel protein-protein interaction module conserved in Ca(2+)-regulated kinases.

Q62896	BET1_RAT	BET1 homolog	8621431	Mammalian vesicle trafficking proteins of the endoplasmic reticulum and Golgi apparatus.

P10896	RCA_ARATH	Ribulose bisphosphate carboxylase/oxygenase activase, chloroplastic	12766230	Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.

Q9SNC3	FLA4_ARATH	Fasciclin-like arabinogalactan protein 4	14517339	Proteomic analysis of glycosylphosphatidylinositol-anchored membrane proteins.

Q8INB9	AKT1_DROME	RAC serine/threonine-protein kinase	10962553	The conserved PI3'K/PTEN/Akt signaling pathway regulates both cell size and survival in Drosophila.

Q9Y709	SKP1_SCHPO	Suppressor of kinetochore protein 1	17016471	Repression of ergosterol level during oxidative stress by fission yeast F-box protein Pof14 independently of SCF.

Q921C5	BICD2_MOUSE	Protein bicaudal D homolog 2	11483508	Mammalian Golgi-associated Bicaudal-D2 functions in the dynein- dynactin pathway by interacting with these complexes.

P29595	NEDD8_MOUSE	NEDD8	12215427	Interaction with Nedd8, a ubiquitin-like protein, enhances the transcriptional activity of the aryl hydrocarbon receptor.

P10795	RBS1A_ARATH	Ribulose bisphosphate carboxylase small chain 1A, chloroplastic	12766230	Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.

Q12179	YP245_YEAST	Uncharacterized protein YPL245W	14562095	Global analysis of protein localization in budding yeast.

Q8I8U2	AP1G_DICDI	AP-1 complex subunit gamma	16478785	Acidic clusters target transmembrane proteins to the contractile vacuole in Dictyostelium cells.

Q9NYF8	BCLF1_HUMAN	Bcl-2-associated transcription factor 1	10330179	Btf, a novel death-promoting transcriptional repressor that interacts with Bcl-2-related proteins.

Q62818	EI2BB_RAT	Translation initiation factor eIF-2B subunit beta	8929216	eIF2B, the guanine nucleotide-exchange factor for eukaryotic initiation factor 2. Sequence conservation between the alpha, beta and delta subunits of eIF2B from mammals and yeast.

P53043	PPT1_YEAST	Serine/threonine-protein phosphatase T	12694636	Characterization of Saccharomyces cerevisiae protein Ser/Thr phosphatase T1 and comparison to its mammalian homolog PP5.

Q9USK8	AGS1_SCHPO	Cell wall alpha-1,3-glucan synthase ags1	9689051	Identification of a putative alpha-glucan synthase essential for cell wall construction and morphogenesis in fission yeast.

P09081	BCD_DROME	Homeotic protein bicoid	10717484	Identification of Drosophila bicoid-interacting proteins using a custom two-hybrid selection.

Q2PJ68	SGK1_CAEEL	Serine/threonine-protein kinase sgk-1	19260765	Rictor/TORC2 regulates Caenorhabditis elegans fat storage, body size, and development through sgk-1.

O74113	CDC45_SCHPO	Cell division control protein 45 homolog	12006645	SpSld3 is required for loading and maintenance of SpCdc45 on chromatin in DNA replication in fission yeast.

O74411	MEU10_SCHPO	Meiotic expression up-regulated protein 10	11895484	Meu10 is required for spore wall maturation in Schizosaccharomyces pombe.

Q9UK45	LSM7_HUMAN	U6 snRNA-associated Sm-like protein LSm7	12165861	Carcinogenesis and translational controls: TACC1 is down-regulated in human cancers and associates with mRNA regulators.

P32780	TF2H1_HUMAN	General transcription factor IIH subunit 1	9852112	Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.

Q24498	RY44_DROME	Ryanodine receptor 44F	10811919	The ryanodine receptor is essential for larval development in Drosophila melanogaster.

Q9P6J2	PCL1_SCHPO	Fe(2+)/Mn(2+) transporter pcl1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O61443	MK14B_DROME	Mitogen-activated protein kinase 14B	9584193	A conserved p38 mitogen-activated protein kinase pathway regulates Drosophila immunity gene expression.

Q24256	BARH2_DROME	Homeobox protein B-H2	1350558	Subtype determination of Drosophila embryonic external sensory organs by redundant homeo box genes BarH1 and BarH2.

P51534	SHE4_YEAST	SWI5-dependent HO expression protein 4	8625407	Mother cell-specific HO expression in budding yeast depends on the unconventional myosin myo4p and other cytoplasmic proteins.

O76050	NEU1A_HUMAN	Neuralized-like protein 1A	9519875	Identification of a human homolog of the Drosophila neuralized gene within the 10q25.1 malignant astrocytoma deletion region.

Q0WPQ2	ETR2_ARATH	Ethylene receptor 2	18577522	Heteromeric interactions among ethylene receptors mediate signaling in Arabidopsis.

Q64191	ASPG_MOUSE	N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	8586423	Molecular cloning, chromosomal assignment, and expression of the mouse aspartylglucosaminidase gene.

Q9M667	RPP13_ARATH	Disease resistance protein RPP13	10743658	RPP13 is a simple locus in Arabidopsis thaliana for alleles that specify downy mildew resistance to different avirulence determinants in Peronospora parasitica.

Q9NZB8	MOCS1_HUMAN	Molybdenum cofactor biosynthesis protein 1	15180982	Characterization of MOCS1A, an oxygen-sensitive iron-sulfur protein involved in human molybdenum cofactor biosynthesis.

Q63262	PO3F3_RAT	POU domain, class 3, transcription factor 3	9632656	Cooperative function of POU proteins and SOX proteins in glial cells.

P51571	SSRD_HUMAN	Translocon-associated protein subunit delta	7492314	Translocon-associated protein TRAP delta and a novel TRAP-like protein are coordinately expressed with pro-opiomelanocortin in Xenopus intermediate pituitary.

Q9Y4X5	ARI1_HUMAN	Protein ariadne-1 homolog	10521492	The ubiquitin-conjugating enzymes UbcH7 and UbcH8 interact with RING finger/IBR motif-containing domains of HHARI and H7-AP1.

Q96DT6	ATG4C_HUMAN	Cysteine protease ATG4C	12446702	Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy.

P42586	NKX22_MOUSE	Homeobox protein Nkx-2.2	14573534	Cross-repressive interaction of the Olig2 and Nkx2.2 transcription factors in developing neural tube associated with formation of a specific physical complex.

Q7TSX9	ZAR1_RAT	Zygote arrest protein 1	12773403	Zygote arrest 1 (Zar1) is an evolutionarily conserved gene expressed in vertebrate ovaries.

P42857	NSG1_HUMAN	Neuron-specific protein family member 1	9013775	Variable subcellular localization of a neuron-specific protein during NTera 2 differentiation into post-mitotic human neurons.

Q99N13	HDAC9_MOUSE	Histone deacetylase 9	11390982	The transcriptional corepressor MITR is a signal-responsive inhibitor of myogenesis.

Q9VYB0	BTHD_DROME	Selenoprotein BthD	11493597	In silico identification of novel selenoproteins in the Drosophila melanogaster genome.

Q9LVI6	RLK90_ARATH	Probable inactive receptor kinase RLK902	15388970	Molecular characterization of two highly homologous receptor-like kinase genes, RLK902 and RKL1, in Arabidopsis thaliana.

Q14324	MYPC2_HUMAN	Myosin-binding protein C, fast-type	8375400	Complete sequence of human fast-type and slow-type muscle myosin- binding-protein C (MyBP-C). Differential expression, conserved domain structure and chromosome assignment.

Q9ZNV8	AHP2_ARATH	Histidine-containing phosphotransfer protein 2	12068096	Two-component signal transduction pathways in Arabidopsis.

Q63ZW7	INADL_MOUSE	InaD-like protein	17452640	Physical interaction between the serotonin transporter and neuronal nitric oxide synthase underlies reciprocal modulation of their activity.

Q90623	MYPT1_CHICK	Protein phosphatase 1 regulatory subunit 12A	15164081	Structural basis of protein phosphatase 1 regulation.

Q9JM54	APR_MOUSE	Phorbol-12-myristate-13-acetate-induced protein 1	15694340	Differential targeting of prosurvival Bcl-2 proteins by their BH3- only ligands allows complementary apoptotic function.

Q15813	TBCE_HUMAN	Tubulin-specific chaperone E	8706133	Pathway leading to correctly folded beta-tubulin.

P52891	NUP84_YEAST	Nucleoporin NUP84	8565072	A novel complex of nucleoporins, which includes Sec13p and a Sec13p homolog, is essential for normal nuclear pores.

O75746	CMC1_HUMAN	Calcium-binding mitochondrial carrier protein Aralar1	11566871	Citrin and aralar1 are Ca(2+)-stimulated aspartate/glutamate transporters in mitochondria.

Q9VFK6	SETD8_DROME	Histone-lysine N-methyltransferase pr-set7	17227890	Aberrant monomethylation of histone H4 lysine 20 activates the DNA damage checkpoint in Drosophila melanogaster.

Q8H115	NA102_ARATH	NAC domain-containing protein 102	19176720	The low-oxygen-induced NAC domain transcription factor ANAC102 affects viability of Arabidopsis seeds following low-oxygen treatment.

Q9HDW0	YO53_SCHPO	Uncharacterized protein P18G5.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P54710	ATNG_HUMAN	Sodium/potassium-transporting ATPase subunit gamma	9048881	Cloning and expression of human cDNA encoding Na+, K(+)-ATPase gamma- subunit.

Q96LA5	FCRL2_HUMAN	Fc receptor-like protein 2	11162587	Molecular cloning and characterization of SPAP1, an inhibitory receptor.

Q9UJV3	TRIM1_HUMAN	Probable E3 ubiquitin-protein ligase MID2	10400986	MID2, a homologue of the Opitz syndrome gene MID1: similarities in a sub-cellular localization and differences in expression during development.

P31391	SSR4_HUMAN	Somatostatin receptor type 4	8100352	Cloning and expression of a human somatostatin-14-selective receptor variant (somatostatin receptor 4) located on chromosome 20.

P32354	MCM10_YEAST	Minichromosome maintenance protein 10	16085704	Mcm10 is required for the maintenance of transcriptional silencing in Saccharomyces cerevisiae.

P52488	UBA2_YEAST	Ubiquitin-activating enzyme E1-like	9312010	The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer.

Q99NB1	ACS2L_MOUSE	Acetyl-coenzyme A synthetase 2-like, mitochondrial	11150295	Acetyl-CoA synthetase 2, a mitochondrial matrix enzyme involved in the oxidation of acetate.

Q8BH07	AR6P6_MOUSE	ADP-ribosylation factor-like protein 6-interacting protein 6	10508919	A novel ADP-ribosylation like factor (ARL-6), interacts with the protein-conducting channel SEC61beta subunit.

Q9Z1T5	DEAF1_MOUSE	Deformed epidermal autoregulatory factor 1 homolog	9860983	Mouse deformed epidermal autoregulatory factor 1 recruits a LIM domain factor, LMO-4, and CLIM coregulators.

Q12464	RUVB2_YEAST	RuvB-like protein 2	14645854	ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex.

Q9UIA9	XPO7_HUMAN	Exportin-7	11024021	Identification of two novel RanGTP-binding proteins belonging to the importin beta superfamily.

P40241	CD9_RAT	CD9 antigen	7823164	CD9, a major platelet cell surface glycoprotein, is a ROCA antigen and is expressed in the nervous system.

O74826	COQ7_SCHPO	Ubiquinone biosynthesis protein coq7	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P26687	TWST1_MOUSE	Twist-related protein 1	16502419	Twist1 dimer selection regulates cranial suture patterning and fusion.

P79958	WT1B_XENLA	Wilms tumor protein homolog B	8917094	cDNA cloning and its pronephros-specific expression of the Wilms' tumor suppressor gene, WT1, from Xenopus laevis.

Q08109	HRD1_YEAST	ERAD-associated E3 ubiquitin-protein ligase HRD1	16873066	Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins.

Q9WVI9	JIP1_MOUSE	C-Jun-amino-terminal kinase-interacting protein 1	10098834	Molecular cloning of multiple splicing variants of JIP-1 preferentially expressed in brain.

Q9SSL9	PEPR1_ARATH	Leucine-rich repeat receptor-like protein kinase PEPR1	18824048	Structure-activity studies of AtPep1, a plant peptide signal involved in the innate immune response.

Q9ULX9	MAFF_HUMAN	Transcription factor MafF	10527846	Molecular cloning of a human MafF homologue, which specifically binds to the oxytocin receptor gene in term myometrium.

P34144	RAC1A_DICDI	Rho-related protein rac1A	15908944	The Diaphanous-related formin dDia2 is required for the formation and maintenance of filopodia.

Q9UBH6	XPR1_HUMAN	Xenotropic and polytropic retrovirus receptor 1	9927670	Cloning and characterization of a cell surface receptor for xenotropic and polytropic murine leukemia viruses.

P24639	ANXA7_DICDI	Annexin A7	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P19835	CEL_HUMAN	Bile salt-activated lipase	2265692	Sequence identity between human pancreatic cholesterol esterase and bile salt-stimulated milk lipase.

Q92819	HAS2_HUMAN	Hyaluronan synthase 2	8798477	Molecular identification of a putative human hyaluronan synthase.

Q9HCS4	TF7L1_HUMAN	Transcription factor 7-like 1	1741298	A gene family of HMG-box transcription factors with homology to TCF- 1.

Q5MNZ9	WIPI1_HUMAN	WD repeat domain phosphoinositide-interacting protein 1	15602573	WIPI-1alpha (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy.

P43351	RAD52_HUMAN	DNA repair protein RAD52 homolog	7774919	The human and mouse homologs of the yeast RAD52 gene: cDNA cloning, sequence analysis, assignment to human chromosome 12p12.2-p13, and mRNA expression in mouse tissues.

Q99502	EYA1_HUMAN	Eyes absent homolog 1	9020840	A human homologue of the Drosophila eyes absent gene underlies branchio-oto-renal (BOR) syndrome and identifies a novel gene family.

P80098	CCL7_HUMAN	C-C motif chemokine 7	7916328	The human MCP-3 gene (SCYA7): cloning, sequence analysis, and assignment to the C-C chemokine gene cluster on chromosome 17q11.2- q12.

P42260	GRIK2_RAT	Glutamate receptor, ionotropic kainate 2	17486098	SUMOylation regulates kainate-receptor-mediated synaptic transmission.

Q8CIX1	RIMS4_RAT	Regulating synaptic membrane exocytosis protein 4	12620390	Genomic definition of RIM proteins: evolutionary amplification of a family of synaptic regulatory proteins.

P56564	EAA1_MOUSE	Excitatory amino acid transporter 1	7903437	Cloning and expression of a glutamate transporter from mouse brain.

Q9Y473	ZN175_HUMAN	Zinc finger protein 175	8838321	Isolation and mapping of a novel human gene encoding a protein containing zinc-finger structures.

O16000	STX1A_CAEEL	Syntaxin-1A homolog	9614171	The Caenorhabditis elegans unc-64 locus encodes a syntaxin that interacts genetically with synaptobrevin.

O75881	CP7B1_HUMAN	25-hydroxycholesterol 7-alpha-hydroxylase	10588945	Structure and functions of human oxysterol 7alpha-hydroxylase cDNAs and gene CYP7B1.

Q61846	MELK_MOUSE	Maternal embryonic leucine zipper kinase	9305775	Cloning and expression of a cDNA encoding a novel protein serine/threonine kinase predominantly expressed in hematopoietic cells.

Q9H9G7	AGO3_HUMAN	Protein argonaute-3	18771919	Importance of translation and nonnucleolytic ago proteins for on- target RNA interference.

Q08689	NAT5_YEAST	N-terminal acetyltransferase A complex subunit NAT5	14517307	The yeast N(alpha)-acetyltransferase NatA is quantitatively anchored to the ribosome and interacts with nascent polypeptides.

Q93Y07	SFR2_ARATH	Beta-glucosidase-like SFR2, chloroplastic	15258268	The SENSITIVE TO FREEZING2 gene, required for freezing tolerance in Arabidopsis thaliana, encodes a beta-glucosidase.

Q06677	SWA2_YEAST	Auxilin-like clathrin uncoating factor SWA2	11553703	Aux1p/Swa2p is required for cortical endoplasmic reticulum inheritance in Saccharomyces cerevisiae.

P34244	HSL1_YEAST	Probable serine/threonine-protein kinase HSL1	8647431	A search for proteins that interact genetically with histone H3 and H4 amino termini uncovers novel regulators of the Swe1 kinase in Saccharomyces cerevisiae.

P83683	OX26_RANES	Orexigenic neuropeptide 26RFa	14657341	Identification of 26RFa, a hypothalamic neuropeptide of the RFamide peptide family with orexigenic activity.

P36156	GTO2_YEAST	Glutathione S-transferase omega-like 2	16709151	Saccharomyces cerevisiae cells have three Omega class glutathione S- transferases acting as 1-Cys thiol transferases.

P34271	CUP4_CAEEL	Acetylcholine receptor-like protein cup-4	11560892	Genetic analysis of endocytosis in Caenorhabditis elegans: coelomocyte uptake defective mutants.

Q9UUK1	YLO6_SCHPO	Uncharacterized protein C1952.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q69ZS0	PZRN3_MOUSE	E3 ubiquitin-protein ligase PDZRN3	17576800	Regulation of synaptic growth and maturation by a synapse-associated E3 ubiquitin ligase at the neuromuscular junction.

Q9M7Q3	AI5L6_ARATH	ABSCISIC ACID-INSENSITIVE 5-like protein 6	10636868	ABFs, a family of ABA-responsive element binding factors.

P26188	MGMT_YEAST	Methylated-DNA--protein-cysteine methyltransferase	2403555	Identification and preliminary characterization of an O6- methylguanine DNA repair methyltransferase in the yeast Saccharomyces cerevisiae.

Q27324	RYK1_DROME	Tyrosine-protein kinase Drl	7656987	The Drosophila learning and memory gene linotte encodes a putative receptor tyrosine kinase homologous to the human RYK gene product.

Q96T23	RSF1_HUMAN	Remodeling and spacing factor 1	11788598	Hepatitis B virus pX interacts with HBXAP, a PHD finger protein to coactivate transcription.

Q9Y661	HS3S4_HUMAN	Heparan sulfate glucosamine 3-O-sulfotransferase 4	9988767	Multiple isoforms of heparan sulfate D-glucosaminyl 3-O- sulfotransferase. Isolation, characterization, and expression of human cDNAs and identification of distinct genomic loci.

Q9M2U1	DOF36_ARATH	Dof zinc finger protein DOF3.6	12887587	Target genes for OBP3, a Dof transcription factor, include novel basic helix-loop-helix domain proteins inducible by salicylic acid.

Q02792	XRN2_YEAST	5'-3' exoribonuclease 2	10805743	Saccharomyces cerevisiae RAI1 (YGL246c) is homologous to human DOM3Z and encodes a protein that binds the nuclear exoribonuclease Rat1p.

P29468	PAP_YEAST	Poly(A) polymerase	1840648	Cloning and expression of the essential gene for poly(A) polymerase from S. cerevisiae.

P86013	LANPA_PAEPO	Lantibiotic paenibacillin	17071789	Isolation and identification of a Paenibacillus polymyxa strain that coproduces a novel lantibiotic and polymyxin.

Q9NQW7	XPP1_HUMAN	Xaa-Pro aminopeptidase 1	11106490	Cloning, expression, and characterization of human cytosolic aminopeptidase P: a single manganese(II)-dependent enzyme.

Q61068	UBPW_MOUSE	Ubiquitin carboxyl-terminal hydrolase DUB-1	8622927	DUB-1, a deubiquitinating enzyme with growth-suppressing activity.

Q9NPE2	NGRN_HUMAN	Neugrin	11118320	Two novel genes, human neugrin and mouse m-neugrin, are upregulated with neuronal differentiation in neuroblastoma cells.

P02340	P53_MOUSE	Cellular tumor antigen p53	11672522	Negative control of p53 by Sir2alpha promotes cell survival under stress.

O44386	ITA3_DROME	Integrin alpha-PS3	9461212	Integrin-mediated short-term memory in Drosophila.

P78798	PEX7_SCHPO	Peroxisomal targeting signal 2 receptor	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8G6Z9	PEPD_BIFLO	Dipeptidase	17601807	Characterization of a Bifidobacterium longum BORI dipeptidase belonging to the U34 family.

O74856	CAF1_SCHPO	Poly(A) ribonuclease pop2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9WUI0	MIXL1_MOUSE	Homeobox protein MIXL1	12117810	Mixl1 is required for axial mesendoderm morphogenesis and patterning in the murine embryo.

P48039	MTR1A_HUMAN	Melatonin receptor type 1A	7946354	Cloning and characterization of a mammalian melatonin receptor that mediates reproductive and circadian responses.

O22781	SUVH2_ARATH	Histone-lysine N-methyltransferase, H3 lysine-9, H3 lysine-27, H4 lysine-20 and cytosine specific SUVH2	11691919	The Arabidopsis thaliana genome contains at least 29 active genes encoding SET domain proteins that can be assigned to four evolutionarily conserved classes.

Q29983	MICA_HUMAN	MHC class I polypeptide-related sequence A	11491531	Interactions of human NKG2D with its ligands MICA, MICB, and homologs of the mouse RAE-1 protein family.

P00786	CATH_RAT	Cathepsin H	2276418	Molecular cloning of rat precursor cathepsin H and the expression of five lysosomal cathepsins in normal tissues and in a rat carcinosarcoma.

O74458	SFC4_SCHPO	Transcription factor tau subunit sfc4	10906331	Isolation and cloning of four subunits of a fission yeast TFIIIC complex that includes an ortholog of the human regulatory protein TFIIICbeta.

Q6XP49	GLIS3_MOUSE	Zinc finger protein GLIS3	14500813	GLIS3, a novel member of the GLIS subfamily of Kruppel-like zinc finger proteins with repressor and activation functions.

P32613	TCA17_YEAST	TRAPP-associated protein TCA17	19416478	TRAPPC2L is a novel, highly conserved TRAPP-interacting protein.

Q9P289	MST4_HUMAN	Serine/threonine-protein kinase MST4	11741893	Cloning of MASK, a novel member of the mammalian germinal center kinase III subfamily, with apoptosis-inducing properties.

Q23858	CALR_DICDI	Calreticulin	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

Q39088	DOF34_ARATH	Dof zinc finger protein DOF3.4	8718629	Interactions between distinct types of DNA binding proteins enhance binding to ocs element promoter sequences.

Q02725	VTC3_YEAST	Vacuolar transporter chaperone 3	11823419	The Vtc proteins in vacuole fusion: coupling NSF activity to V(0) trans-complex formation.

Q96HR8	NAF1_HUMAN	H/ACA ribonucleoprotein complex non-core subunit NAF1	16618814	Stepwise RNP assembly at the site of H/ACA RNA transcription in human cells.

P15315	CUP2_YEAST	Transcriptional activator protein CUP2	2674688	The CUP2 gene product, regulator of yeast metallothionein expression, is a copper-activated DNA-binding protein.

Q9Y294	ASF1A_HUMAN	Histone chaperone ASF1A	10759893	A human homologue of yeast anti-silencing factor has histone chaperone activity.

P21951	DPOE_YEAST	DNA polymerase epsilon catalytic subunit A	1537345	DNA polymerase II, the probable homolog of mammalian DNA polymerase epsilon, replicates chromosomal DNA in the yeast Saccharomyces cerevisiae.

P01765	HV304_HUMAN	Ig heavy chain V-III region TIL	409716	Immunoglobulin structure and genetics. Identity between variable regions of a mu and a gamma2 chain.

Q8GZA8	ULT1_ARATH	Protein ULTRAPETALA 1	15673576	ULTRAPETALA1 encodes a SAND domain putative transcriptional regulator that controls shoot and floral meristem activity in Arabidopsis.

P19525	E2AK2_HUMAN	Interferon-induced, double-stranded RNA-activated protein kinase	8576172	The P58 cellular inhibitor complexes with the interferon-induced, double-stranded RNA-dependent protein kinase, PKR, to regulate its autophosphorylation and activity.

P08173	ACM4_HUMAN	Muscarinic acetylcholine receptor M4	3443095	Distinct primary structures, ligand-binding properties and tissue- specific expression of four human muscarinic acetylcholine receptors.

Q95YL5	PEFA_DICDI	Penta-EF hand domain-containing protein 1	11927596	Biochemical characterization of two analogues of the apoptosis-linked gene 2 protein in Dictyostelium discoideum and interaction with a physiological partner in mammals, murine Alix.

Q10198	NDC80_SCHPO	Kinetochore protein ndc80	17035632	Reconstruction of the kinetochore during meiosis in fission yeast Schizosaccharomyces pombe.

A2A935	PRD16_MOUSE	PR domain zinc finger protein 16	19641492	Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-beta transcriptional complex.

P32602	SEC17_YEAST	Alpha-soluble NSF attachment protein	1601878	The yeast SEC17 gene product is functionally equivalent to mammalian alpha-SNAP protein.

Q9LFL0	CSLD2_ARATH	Cellulose synthase-like protein D2	16618929	Mapping the Arabidopsis organelle proteome.

Q02363	ID2_HUMAN	DNA-binding protein inhibitor ID-2	1741406	A human Id-like helix-loop-helix protein expressed during early development.

O80931	AS1_ARATH	Transcription factor AS1	11882937	ASYMMETRIC LEAVES1, an Arabidopsis gene that is involved in the control of cell differentiation in leaves.

P32342	SRP21_YEAST	Signal recognition particle subunit SRP21	7925282	Subunits of the Saccharomyces cerevisiae signal recognition particle required for its functional expression.

P45568	DXR_ECOLI	1-deoxy-D-xylulose 5-phosphate reductoisomerase	9707569	A 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzing the formation of 2-C-methyl-D-erythritol 4-phosphate in an alternative nonmevalonate pathway for terpenoid biosynthesis.

Q8NDT2	RB15B_HUMAN	Putative RNA-binding protein 15B	16129689	Interaction of the Epstein-Barr virus mRNA export factor EB2 with human Spen proteins SHARP, OTT1, and a novel member of the family, OTT3, links Spen proteins with splicing regulation and mRNA export.

P38339	RGD1_YEAST	RHO GTPase-activating protein RGD1	16087742	The Rgd1p Rho GTPase-activating protein and the Mid2p cell wall sensor are required at low pH for protein kinase C pathway activation and cell survival in Saccharomyces cerevisiae.

O74994	RNG3_SCHPO	Ring assembly protein 3	10852821	Fission yeast Rng3p: an UCS-domain protein that mediates myosin II assembly during cytokinesis.

Q03600	INA1_CAEEL	Integrin alpha ina-1	9247263	Neuronal migrations and axon fasciculation are disrupted in ina-1 integrin mutants.

O00463	TRAF5_HUMAN	TNF receptor-associated factor 5	9511754	Cloning and characterization of a cDNA encoding the human homolog of tumor necrosis factor receptor-associated factor 5 (TRAF5).

P53331	REXO1_YEAST	RNA exonuclease 1	10359084	Purification of Saccharomyces cerevisiae RNase H(70) and identification of the corresponding gene.

O94874	UFL1_HUMAN	E3 UFM1-protein ligase 1	20018847	A novel type of E3 ligase for the Ufm1 conjugation system.

O14904	WNT9A_HUMAN	Protein Wnt-9a	9441749	Isolation of two novel WNT genes, WNT14 and WNT15, one of which (WNT15) is closely linked to WNT3 on human chromosome 17q21.

O94545	KA113_SCHPO	Importin beta-like protein kap113	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P30443	1A01_HUMAN	HLA class I histocompatibility antigen, A-1 alpha chain	2715640	Diversity and diversification of HLA-A,B,C alleles.

O60187	SID4_SCHPO	Septation initiation protein sid4	15062098	Sid4p-Cdc11p assembles the septation initiation network and its regulators at the S. pombe SPB.

Q07732	ADY3_YEAST	Accumulates dyads protein 3	11973299	Ady3p links spindle pole body function to spore wall synthesis in Saccharomyces cerevisiae.

Q9Y5E5	PCDB4_HUMAN	Protocadherin beta-4	11322959	The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number.

P64604	MLAD_ECOLI	Probable phospholipid ABC transporter-binding protein mlaD	19383799	An ABC transport system that maintains lipid asymmetry in the gram- negative outer membrane.

Q86VZ5	SMS1_HUMAN	Phosphatidylcholine:ceramide cholinephosphotransferase 1	14685263	Identification of a family of animal sphingomyelin synthases.

P40339	RFC4_YEAST	Replication factor C subunit 4	12604797	Yeast Rad17/Mec3/Ddc1: a sliding clamp for the DNA damage checkpoint.

Q9FFK1	SYP31_ARATH	Syntaxin-31	12427991	Characterization of AtCDC48. Evidence for multiple membrane fusion mechanisms at the plane of cell division in plants.

P32179	HAL2_YEAST	3'(2'),5'-bisphosphate nucleotidase	8393782	Salt tolerance and methionine biosynthesis in Saccharomyces cerevisiae involve a putative phosphatase gene.

P24530	EDNRB_HUMAN	Endothelin B receptor	8001158	A missense mutation of the endothelin-B receptor gene in multigenic Hirschsprung's disease.

P20433	RPB4_YEAST	DNA-directed RNA polymerase II subunit RPB4	11087726	Dissociable Rpb4-Rpb7 subassembly of RNA polymerase II binds to single-strand nucleic acid and mediates a post-recruitment step in transcription initiation.

Q9UBN4	TRPC4_HUMAN	Short transient receptor potential channel 4	19996314	Cell-cell contact formation governs Ca2+ signaling by TRPC4 in the vascular endothelium: evidence for a regulatory TRPC4-beta-catenin interaction.

Q9UQ13	SHOC2_HUMAN	Leucine-rich repeat protein SHOC-2	9674433	SUR-8, a conserved Ras-binding protein with leucine-rich repeats, positively regulates Ras-mediated signaling in C. elegans.

Q14A28	PROK1_MOUSE	Prokineticin-1	12746324	Mouse endocrine gland-derived vascular endothelial growth factor: a distinct expression pattern from its human ortholog suggests different roles as a regulator of organ-specific angiogenesis.

Q9I7K0	JUPIT_DROME	Microtubule-associated protein Jupiter	16518797	Jupiter, a new Drosophila protein associated with microtubules.

P21549	SPYA_HUMAN	Serine--pyruvate aminotransferase	2363689	Human peroxisomal L-alanine: glyoxylate aminotransferase. Evolutionary loss of a mitochondrial targeting signal by point mutation of the initiation codon.

Q9USU3	FBH1_SCHPO	F-box DNA helicase protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O54834	RHG06_MOUSE	Rho GTPase-activating protein 6	10699171	Functional analysis of ARHGAP6, a novel GTPase-activating protein for RhoA.

Q6WNK7	SUS1_YEAST	Protein SUS1	18923079	Sus1 is recruited to coding regions and functions during transcription elongation in association with SAGA and TREX2.

Q96V54	CREB_EMENI	Ubiquitin carboxyl-terminal hydrolase creB	11918805	The WD40-repeat protein CreC interacts with and stabilizes the deubiquitinating enzyme CreB in vivo in Aspergillus nidulans.

Q9H9Y2	RPF1_HUMAN	Ribosome production factor 1	12429849	Functional proteomic analysis of human nucleolus.

P35373	AGTRB_XENLA	Type-1 angiotensin II receptor B	8355665	Isolation and expression of a novel angiotensin II receptor from Xenopus laevis heart.

P32183	FOXA3_RAT	Hepatocyte nuclear factor 3-gamma	9369482	The role of HNF1alpha, HNF3gamma, and cyclic AMP in glucose-6- phosphatase gene activation.

O75881	CP7B1_HUMAN	25-hydroxycholesterol 7-alpha-hydroxylase	9802883	Identification of a new inborn error in bile acid synthesis: mutation of the oxysterol 7-alpha-hydroxylase gene causes severe neonatal liver disease.

P20673	ARLY_RAT	Argininosuccinate lyase	2789519	Structure of the rat argininosuccinate lyase gene: close similarity to chicken delta-crystallin genes.

P37288	V1AR_HUMAN	Vasopressin V1a receptor	8106369	Molecular cloning, sequencing, and functional expression of a cDNA encoding the human V1a vasopressin receptor.

Q9Y3C5	RNF11_HUMAN	RING finger protein 11	14755250	An RNF11: Smurf2 complex mediates ubiquitination of the AMSH protein.

Q9HFE6	YNW6_SCHPO	Uncharacterized RNA-binding protein P16F5.06	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8IUQ0	CLVS1_HUMAN	Clavesin-1	19651769	The clavesin family: neuron-specific lipid- and clathrin-binding Sec14 proteins regulating lysosomal morphology.

P35131	UBC8_ARATH	Ubiquitin-conjugating enzyme E2 8	17355433	A mutation in NLA, which encodes a RING-type ubiquitin ligase, disrupts the adaptability of Arabidopsis to nitrogen limitation.

P78380	OLR1_HUMAN	Oxidized low-density lipoprotein receptor 1	9052782	An endothelial receptor for oxidized low-density lipoprotein.

P32485	HOG1_YEAST	Mitogen-activated protein kinase HOG1	7681220	An osmosensing signal transduction pathway in yeast.

Q9UQC2	GAB2_HUMAN	GRB2-associated-binding protein 2	15750601	The molecular scaffold Gab2 is a crucial component of RANK signaling and osteoclastogenesis.

P24485	CD53_RAT	Leukocyte surface antigen CD53	2017181	The rat leukocyte antigen MRC OX-44 is a member of a new family of cell surface proteins which appear to be involved in growth regulation.

O65572	CCD1_ARATH	Carotenoid 9,10(9',10')-cleavage dioxygenase 1	11316814	Characterization of a novel carotenoid cleavage dioxygenase from plants.

Q9UKV8	AGO2_HUMAN	Protein argonaute-2	14749716	Characterization of the interactions between mammalian PAZ PIWI domain proteins and Dicer.

P03372	ESR1_HUMAN	Estrogen receptor	12917342	BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation.

P13674	P4HA1_HUMAN	Prolyl 4-hydroxylase subunit alpha-1	2543975	Molecular cloning of the alpha-subunit of human prolyl 4-hydroxylase: the complete cDNA-derived amino acid sequence and evidence for alternative splicing of RNA transcripts.

O60054	ARP10_SCHPO	Actin-like protein arp10	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P38555	YPT31_YEAST	GTP-binding protein YPT31/YPT8	11943201	Identification of the novel proteins Yip4p and Yip5p as Rab GTPase interacting factors.

P26992	CNTFR_HUMAN	Ciliary neurotrophic factor receptor subunit alpha	1648265	The receptor for ciliary neurotrophic factor.

P16157	ANK1_HUMAN	Ankyrin-1	12527750	Binding of an ankyrin-1 isoform to obscurin suggests a molecular link between the sarcoplasmic reticulum and myofibrils in striated muscles.

Q9NZR4	VSX1_HUMAN	Visual system homeobox 1	10673340	Isolation and characterization of a novel human paired-like homeodomain-containing transcription factor gene, VSX1, expressed in ocular tissues.

Q9NSA1	FGF21_HUMAN	Fibroblast growth factor 21	19117008	Different roles of N- and C- termini in the functional activity of FGF21.

Q9Z0S9	PRAF1_MOUSE	Prenylated Rab acceptor protein 1	11335720	Prenylated Rab acceptor protein is a receptor for prenylated small GTPases.

Q61039	HAND2_MOUSE	Heart- and neural crest derivatives-expressed protein 2	9171826	Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND.

Q05502	HHEX_CHICK	Hematopoietically-expressed homeobox protein HHEX	1360645	Identification of a novel vertebrate homeobox gene expressed in haematopoietic cells.

P20689	MYLK2_RAT	Myosin light chain kinase 2, skeletal/cardiac muscle	2839493	Isolation of the cDNA encoding rat skeletal muscle myosin light chain kinase. Sequence and tissue distribution.

O60907	TBL1X_HUMAN	F-box-like/WD repeat-containing protein TBL1X	12628926	Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1.

Q9LXV5	NFYA1_ARATH	Nuclear transcription factor Y subunit A-1	9662544	Multiple genes encoding the conserved CCAAT-box transcription factor complex are expressed in Arabidopsis.

O95456	PSMG1_HUMAN	Proteasome assembly chaperone 1	16251969	A heterodimeric complex that promotes the assembly of mammalian 20S proteasomes.

P28472	GBRB3_HUMAN	Gamma-aminobutyric acid receptor subunit beta-3	1664410	The GABAA receptor beta 3 subunit gene: characterization of a human cDNA from chromosome 15q11q13 and mapping to a region of conserved synteny on mouse chromosome 7.

Q6A2H4	IL10_CHICK	Interleukin-10	16996141	Analysis of chicken cytokine and chemokine gene expression following Eimeria acervulina and Eimeria tenella infections.

Q9P1Y5	CAMP3_HUMAN	Calmodulin-regulated spectrin-associated protein 3	19041755	Anchorage of microtubule minus ends to adherens junctions regulates epithelial cell-cell contacts.

P54103	DNJC2_MOUSE	DnaJ homolog subfamily C member 2	7559602	MIDA1, a protein associated with Id, regulates cell growth.

P51136	GSK3_DICDI	Glycogen synthase kinase-3	7813009	Glycogen synthase kinase 3 regulates cell fate in Dictyostelium.

P25103	NK1R_HUMAN	Substance-P receptor	1657150	Human substance P receptor (NK-1): organization of the gene, chromosome localization, and functional expression of cDNA clones.

Q16649	NFIL3_HUMAN	Nuclear factor interleukin-3-regulated protein	1620116	Transcriptional repression by a novel member of the bZIP family of transcription factors.

Q9URQ5	HTL1_YEAST	High temperature lethal protein 1	12684875	Dissecting the pet18 mutation in Saccharomyces cerevisiae: HTL1 encodes a 7-kDa polypeptide that interacts with components of the RSC complex.

P54253	ATX1_HUMAN	Ataxin-1	12093161	USP7, a ubiquitin-specific protease, interacts with ataxin-1, the SCA1 gene product.

O94584	YQ7C_SCHPO	Uncharacterized CDP-alcohol phosphatidyltransferase class-I family protein C1442.12	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P51610	HCFC1_HUMAN	Host cell factor 1	10871379	Zhangfei: a second cellular protein interacts with herpes simplex virus accessory factor HCF in a manner similar to Luman and VP16.

Q9SHJ5	GPAT1_ARATH	Glycerol-3-phosphate acyltransferase 1	12897259	Arabidopsis AtGPAT1, a member of the membrane-bound glycerol-3- phosphate acyltransferase gene family, is essential for tapetum differentiation and male fertility.

P08458	SPS1_YEAST	Sporulation-specific protein 1	14562095	Global analysis of protein localization in budding yeast.

P05205	HP1_DROME	Heterochromatin protein 1	12808023	Drosophila MCM10 interacts with members of the prereplication complex and is required for proper chromosome condensation.

P32563	VPH1_YEAST	V-type proton ATPase subunit a, vacuolar isoform	1385813	The VPH1 gene encodes a 95-kDa integral membrane polypeptide required for in vivo assembly and activity of the yeast vacuolar H(+)-ATPase.

Q9UYD1	TRM56_PYRAB	tRNA ribose 2'-O-methyltransferase aTrm56	15987815	The Cm56 tRNA modification in archaea is catalyzed either by a specific 2'-O-methylase, or a C/D sRNP.

Q9YHY9	OTC_CHICK	Ornithine carbamoyltransferase, mitochondrial	9792920	Chicken ornithine transcarbamylase gene, structure, regulation, and chromosomal assignment: repetitive sequence motif in intron 3 regulates this enzyme activity.

Q9D9V4	RSPH9_MOUSE	Radial spoke head protein 9 homolog	19200523	Mutations in radial spoke head protein genes RSPH9 and RSPH4A cause primary ciliary dyskinesia with central-microtubular-pair abnormalities.

Q15651	HMGN3_HUMAN	High mobility group nucleosome-binding domain-containing protein 3	7776974	Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor.

P97433	RGNEF_MOUSE	Rho-guanine nucleotide exchange factor	15378065	Control of axonal branching and synapse formation by focal adhesion kinase.

P13804	ETFA_HUMAN	Electron transfer flavoprotein subunit alpha, mitochondrial	3170610	Molecular cloning and nucleotide sequence of cDNAs encoding the alpha-subunit of human electron transfer flavoprotein.

Q9V8P9	TOPRS_DROME	E3 ubiquitin-protein ligase Topors	14871887	Drosophila Topors is a RING finger-containing protein that functions as a ubiquitin-protein isopeptide ligase for the hairy basic helix- loop-helix repressor protein.

Q9SW80	BLH2_ARATH	BEL1-like homeodomain protein 2	17873098	The Arabidopsis BEL1-LIKE HOMEODOMAIN proteins SAW1 and SAW2 act redundantly to regulate KNOX expression spatially in leaf margins.

Q9Y5R2	MMP24_HUMAN	Matrix metalloproteinase-24	10363975	Identification and characterization of human MT5-MMP, a new membrane- bound activator of progelatinase a overexpressed in brain tumors.

Q8TF76	HASP_HUMAN	Serine/threonine-protein kinase haspin	11228240	Cloning and characterization of human haspin gene encoding haploid germ cell-specific nuclear protein kinase.

P63345	ARC_MYCTU	Proteasome-associated ATPase	20203624	The mycobacterial Mpa-proteasome unfolds and degrades pupylated substrates by engaging Pup's N-terminus.

Q08050	FOXM1_HUMAN	Forkhead box protein M1	9032290	Hepatocyte nuclear factor 3/fork head homolog 11 is expressed in proliferating epithelial and mesenchymal cells of embryonic and adult tissues.

P33013	DACD_ECOLI	D-alanyl-D-alanine carboxypeptidase dacD	8955390	dacD, an Escherichia coli gene encoding a novel penicillin-binding protein (PBP6b) with DD-carboxypeptidase activity.

Q03774	TRM82_YEAST	tRNA (guanine-N(7)-)-methyltransferase subunit TRM82	12403464	Two proteins that form a complex are required for 7-methylguanosine modification of yeast tRNA.

B7ZS96	TTHY_XENLA	Transthyretin	12553426	The effects of endocrine-disrupting chemicals on thyroid hormone binding to Xenopus laevis transthyretin and thyroid hormone receptor.

P46639	KNAT1_ARATH	Homeobox protein knotted-1-like 1	7866029	A knotted1-like homeobox gene in Arabidopsis is expressed in the vegetative meristem and dramatically alters leaf morphology when overexpressed in transgenic plants.

Q91ZU9	NMD3B_MOUSE	Glutamate [NMDA] receptor subunit 3B	11717388	Motoneuron-specific expression of NR3B, a novel NMDA-type glutamate receptor subunit that works in a dominant-negative manner.

P62714	PP2AB_HUMAN	Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	2849765	The nucleotide sequence of the cDNA encoding the human lung protein phosphatase 2A beta catalytic subunit.

Q9Y2T6	GPR55_HUMAN	G-protein coupled receptor 55	19805329	The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo.

P51693	APLP1_HUMAN	Amyloid-like protein 1	9521588	Structure of the human amyloid-precursor-like protein gene APLP1 at 19q13.1.

P36033	FRE2_YEAST	Ferric/cupric reductase transmembrane component 2	9153234	The yeast Fre1p/Fre2p cupric reductases facilitate copper uptake and are regulated by the copper-modulated Mac1p activator.

O43491	E41L2_HUMAN	Band 4.1-like protein 2	9598318	Cloning and characterization of 4.1G (EPB41L2), a new member of the skeletal protein 4.1 (EPB41) gene family.

O95633	FSTL3_HUMAN	Follistatin-related protein 3	17878677	Characterization of follistatin-related gene as a negative regulatory factor for activin family members during mouse heart development.

P30678	GNA15_MOUSE	Guanine nucleotide-binding protein subunit alpha-15	8838318	Gene structure of murine Gna11 and Gna15: tandemly duplicated Gq class G protein alpha subunit genes.

P29590	PML_HUMAN	Probable transcription factor PML	12773567	PML colocalizes with and stabilizes the DNA damage response protein TopBP1.

Q12962	TAF10_HUMAN	Transcription initiation factor TFIID subunit 10	11564863	Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage- binding factors in vivo.

Q9I928	FUCL4_ANGJA	Fucolectin-4	10924498	Multiplicity, structures, and endocrine and exocrine natures of eel fucose-binding lectins.

Q9FL28	FLS2_ARATH	LRR receptor-like serine/threonine-protein kinase FLS2	19062288	Plant pattern-recognition receptor FLS2 is directed for degradation by the bacterial ubiquitin ligase AvrPtoB.

Q24168	ORC2_DROME	Origin recognition complex subunit 2	12808023	Drosophila MCM10 interacts with members of the prereplication complex and is required for proper chromosome condensation.

P10253	LYAG_HUMAN	Lysosomal alpha-glucosidase	16917947	Mutation profile of the GAA gene in 40 Italian patients with late onset glycogen storage disease type II.

Q02260	SMD1_YEAST	Small nuclear ribonucleoprotein Sm D1	8430095	Convergent transcripts of the yeast PRP38-SMD1 locus encode two essential splicing factors, including the D1 core polypeptide of small nuclear ribonucleoprotein particles.

Q00526	CDK3_HUMAN	Cell division protein kinase 3	1639063	A family of human cdc2-related protein kinases.

Q8K3Y3	LN28A_MOUSE	Protein lin-28 homolog A	18604195	A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment.

Q9GZQ8	MLP3B_HUMAN	Microtubule-associated proteins 1A/1B light chain 3B	15187094	HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtubule-associated protein light chain 3- and GABAA receptor-associated protein-phospholipid conjugates.

Q84KJ5	CRYD_ARATH	Cryptochrome DASH, chloroplastic/mitochondrial	12834405	An Arabidopsis protein closely related to Synechocystis cryptochrome is targeted to organelles.

Q12824	SNF5_HUMAN	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1	8895581	Purification and biochemical heterogeneity of the mammalian SWI-SNF complex.

Q9P7H9	YIT3_SCHPO	Uncharacterized transcriptional regulatory protein C105.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q50L43	PA24D_MOUSE	Cytosolic phospholipase A2 delta	15866882	Identification of novel cytosolic phospholipase A(2)s, murine cPLA(2)delta, epsilon, and zeta, which form a gene cluster with cPLA(2)beta.

P63000	RAC1_HUMAN	Ras-related C3 botulinum toxin substrate 1	7673236	Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity.

Q9NPH9	IL26_HUMAN	Interleukin-26	18483078	The role of the novel Th17 cytokine IL-26 in intestinal inflammation.

Q96HY6	DDRGK_HUMAN	DDRGK domain-containing protein 1	20018847	A novel type of E3 ligase for the Ufm1 conjugation system.

Q9SRH9	SNL1_ARATH	Paired amphipathic helix protein Sin3-like 1	19962994	PAH-domain-specific interactions of the Arabidopsis transcription coregulator SIN3-LIKE1 (SNL1) with telomere-binding protein 1 and ALWAYS EARLY2 Myb-DNA binding factors.

O22476	BRI1_ARATH	Protein BRASSINOSTEROID INSENSITIVE 1	12150929	BAK1, an Arabidopsis LRR receptor-like protein kinase, interacts with BRI1 and modulates brassinosteroid signaling.

Q92560	BAP1_HUMAN	Ubiquitin carboxyl-terminal hydrolase BAP1	19815555	The deubiquitinating enzyme BAP1 regulates cell growth via interaction with HCF-1.

O80992	PYL2_ARATH	Abscisic acid receptor PYL2	19898420	A gate-latch-lock mechanism for hormone signalling by abscisic acid receptors.

P05923	VPU_HV1BR	Protein Vpu	9660940	A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif.

Q9M5A9	GPT1_ARATH	Glucose-6-phosphate/phosphate translocator 1, chloroplastic	15722468	The Arabidopsis plastidic glucose 6-phosphate/phosphate translocator GPT1 is essential for pollen maturation and embryo sac development.

Q9GZC8	SID1_CAEEL	Systemic RNA interference defective protein 1	11834782	Systemic RNAi in C. elegans requires the putative transmembrane protein SID-1.

P35123	UBP4_MOUSE	Ubiquitin carboxyl-terminal hydrolase 4	11571651	Association of UNP, a ubiquitin-specific protease, with the pocket proteins pRb, p107 and p130.

Q11002	CANA_DROME	Calpain-A	10446155	Characterization of two recombinant Drosophila calpains. CALPA and a novel homolog, CALPB.

P81133	SIM1_HUMAN	Single-minded homolog 1	9199934	Cloning of two human homologs of the Drosophila single-minded gene SIM1 on chromosome 6q and SIM2 on 21q within the Down syndrome chromosomal region.

Q9CWU6	UQCC_MOUSE	Ubiquinol-cytochrome c reductase complex chaperone CBP3 homolog	11118897	Expression of a novel mouse gene 'mbFZb' in distinct regions of the developing nervous system and the adult brain.

Q8RWD9	ACBP5_ARATH	Acyl-CoA-binding domain-containing protein 5	18773301	Arabidopsis acyl-CoA-binding proteins ACBP4 and ACBP5 are subcellularly localized to the cytosol and ACBP4 depletion affects membrane lipid composition.

O43895	XPP2_HUMAN	Xaa-Pro aminopeptidase 2	9375790	Cloning and tissue distribution of human membrane-bound aminopeptidase P.

Q86B87	MMD4_DROME	Modifier of mdg4	7664338	A Drosophila protein that imparts directionality on a chromatin insulator is an enhancer of position-effect variegation.

Q13137	CACO2_HUMAN	Calcium-binding and coiled-coil domain-containing protein 2	9230084	Cellular localization, expression, and structure of the nuclear dot protein 52.

Q9UHY1	NRBP_HUMAN	Nuclear receptor-binding protein	15084397	The non-structural 3 (NS3) protein of dengue virus type 2 interacts with human nuclear receptor binding protein and is associated with alterations in membrane structure.

O94565	YGD8_SCHPO	Uncharacterized mannosyltransferase C1773.08c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9XEE2	ANXD2_ARATH	Annexin D2	16531057	Expression profiling of the Arabidopsis annexin gene family during germination, de-etiolation and abiotic stress.

Q93ZB9	FACR3_ARATH	Fatty acyl-CoA reductase 3	19062129	Functional expression of five Arabidopsis fatty acyl-CoA reductase genes in Escherichia coli.

Q9UIQ6	LCAP_HUMAN	Leucyl-cystinyl aminopeptidase	9177475	The complete amino acid sequence of human placental oxytocinase.

Q9Y3Q0	NALD2_HUMAN	N-acetylated-alpha-linked acidic dipeptidase 2	10085079	Isolation and expression of novel human glutamate carboxypeptidases with N-acetylated alpha-linked acidic dipeptidase and dipeptidyl peptidase IV activity.

P48509	CD151_HUMAN	CD151 antigen	8627808	SFA-1, a novel cellular gene induced by human T-cell leukemia virus type 1, is a member of the transmembrane 4 superfamily.

P40474	QDR2_YEAST	Quinidine resistance protein 2	17189489	Saccharomyces cerevisiae multidrug resistance transporter Qdr2 is implicated in potassium uptake, providing a physiological advantage to quinidine-stressed cells.

Q8LEK4	TRL21_ARATH	Thioredoxin-like 2-1, chloroplastic	19109414	A small family of chloroplast atypical thioredoxins.

Q06164	MMS22_YEAST	Methyl methanesulfonate-sensitivity protein 22	15718301	Mms22p protects Saccharomyces cerevisiae from DNA damage induced by topoisomerase II.

Q8L7J2	BGL06_ORYSJ	Beta-glucosidase 6	19587102	Structural and enzymatic characterization of Os3BGlu6, a rice beta- glucosidase hydrolyzing hydrophobic glycosides and (1->3)- and (1->2)- linked disaccharides.

P56932	2ABD_RAT	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform	10556517	Cloning and characterization of B delta, a novel regulatory subunit of protein phosphatase 2A.

P40517	YRB2_YEAST	Ran-specific GTPase-activating protein 2	9636166	A member of the Ran-binding protein family, Yrb2p, is involved in nuclear protein export.

Q9Y4B6	VPRBP_HUMAN	Protein VPRBP	20178741	Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4(DCAF1) in the nucleus.

Q8TAT5	NEIL3_HUMAN	Endonuclease 8-like 3	19121397	Expression and purification of NEIL3, a human DNA glycosylase homolog.

Q9UT81	UBX3_SCHPO	UBX domain-containing protein 3	15120077	The Ubx2 and Ubx3 cofactors direct Cdc48 activity to proteolytic and nonproteolytic ubiquitin-dependent processes.

Q8BJM5	ZNT6_MOUSE	Zinc transporter 6	11997387	Functional characterization of a novel mammalian zinc transporter, ZnT6.

Q9SSL9	PEPR1_ARATH	Leucine-rich repeat receptor-like protein kinase PEPR1	16785433	The cell surface leucine-rich repeat receptor for AtPep1, an endogenous peptide elicitor in Arabidopsis, is functional in transgenic tobacco cells.

P36406	TRI23_HUMAN	E3 ubiquitin-protein ligase TRIM23	8473324	ARD 1, a 64-kDa guanine nucleotide-binding protein with a carboxyl- terminal ADP-ribosylation factor domain.

Q9UN37	VPS4A_HUMAN	Vacuolar protein sorting-associated protein 4A	11559748	CHMP1 functions as a member of a newly defined family of vesicle trafficking proteins.

P63321	RALA_MOUSE	Ras-related protein Ral-A	8570186	A putative effector of Ral has homology to Rho/Rac GTPase activating proteins.

P01700	LV102_HUMAN	Ig lambda chain V-I region HA	5532227	Amino acid sequence of human lambda chains. II. Chymotryptic peptides and sequence of protein Ha.

Q04003	SAS4_YEAST	Something about silencing protein 4	11731479	The yeast SAS (something about silencing) protein complex contains a MYST-type putative acetyltransferase and functions with chromatin assembly factor ASF1.

Q9PT60	RBP1A_XENLA	RalA-binding protein 1-A	9753634	Identification and characterization in Xenopus of XsmgGDS, a RalB- binding protein.

P49107	PSAN_ARATH	Photosystem I reaction center subunit N, chloroplastic	11826309	Central functions of the lumenal and peripheral thylakoid proteome of Arabidopsis determined by experimentation and genome-wide prediction.

P07347	ARD1_YEAST	N-terminal acetyltransferase A complex catalytic subunit ARD1	2551674	Identification and characterization of genes and mutants for an N- terminal acetyltransferase from yeast.

Q9XH48	TIM13_ARATH	Mitochondrial import inner membrane translocase subunit Tim13	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P63000	RAC1_HUMAN	Ras-related C3 botulinum toxin substrate 1	11163217	Modulation of host signaling by a bacterial mimic: structure of the Salmonella effector SptP bound to Rac1.

P42345	MTOR_HUMAN	Serine/threonine-protein kinase mTOR	18497260	The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1.

O08699	PGDH_RAT	15-hydroxyprostaglandin dehydrogenase [NAD+]	9099857	Cloning and expression of the cDNA for rat NAD+-dependent 15- hydroxyprostaglandin dehydrogenase.

Q9FMD7	Y5659_ARATH	Probable inactive receptor kinase At5g16590	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

P83917	CBX1_MOUSE	Chromobox protein homolog 1	10747027	The structure of mouse HP1 suggests a unique mode of single peptide recognition by the shadow chromo domain dimer.

Q7Z7M8	B3GN8_HUMAN	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8	15620693	A novel beta1,3-N-acetylglucosaminyltransferase (beta3Gn-T8), which synthesizes poly-N-acetyllactosamine, is dramatically upregulated in colon cancer.

P30630	LIN9_CAEEL	Protein lin-9	17075059	Some C. elegans class B synthetic multivulva proteins encode a conserved LIN-35 Rb-containing complex distinct from a NuRD-like complex.

O88735	MAP7_MOUSE	Ensconsin	14517216	Microtubule-associated protein 7 increases the membrane expression of transient receptor potential vanilloid 4 (TRPV4).

P32246	CCR1_HUMAN	C-C chemokine receptor type 1	7505609	Molecular cloning of cDNAs encoding a LD78 receptor and putative leukocyte chemotactic peptide receptors.

P39104	PIK1_YEAST	Phosphatidylinositol 4-kinase PIK1	8194527	PIK1, an essential phosphatidylinositol 4-kinase associated with the yeast nucleus.

Q9US34	YFZ7_SCHPO	Uncharacterized aminotransferase C1039.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q99640	PMYT1_HUMAN	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	10373560	Overproduction of human Myt1 kinase induces a G2 cell cycle delay by interfering with the intracellular trafficking of Cdc2-cyclin B1 complexes.

Q8UUG8	5HT2B_TETFL	5-hydroxytryptamine receptor 2B	11744166	The serotonin 5-HT2B receptor from the puffer fish Tetraodon fluviatilis: cDNA cloning, genomic organization and alternatively spliced variants.

P84634	DCL4_ARATH	Dicer-like protein 4	15821876	Specific interactions between Dicer-like proteins and HYL1/DRB-family dsRNA-binding proteins in Arabidopsis thaliana.

Q9UKI8	TLK1_HUMAN	Serine/threonine-protein kinase tousled-like 1	12660173	Human tousled like kinases are targeted by an ATM- and Chk1-dependent DNA damage checkpoint.

P25963	IKBA_HUMAN	NF-kappa-B inhibitor alpha	9865694	The crystal structure of the IkappaBalpha/NF-kappaB complex reveals mechanisms of NF-kappaB inactivation.

Q54IP0	DNJC7_DICDI	DnaJ homolog subfamily C member 7 homolog	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P29803	ODPAT_HUMAN	Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial	2249846	A testis-specific form of the human pyruvate dehydrogenase E1 alpha subunit is coded for by an intronless gene on chromosome 4.

P39722	GEM1_YEAST	Mitochondrial Rho GTPase 1	15479738	Yeast Miro GTPase, Gem1p, regulates mitochondrial morphology via a novel pathway.

Q6NZI2	PTRF_HUMAN	Polymerase I and transcript release factor	9582279	Cloning and functional characterization of PTRF, a novel protein which induces dissociation of paused ternary transcription complexes.

Q9UK73	FEM1B_HUMAN	Protein fem-1 homolog B	10542291	F1Aalpha, a death receptor-binding protein homologous to the Caenorhabditis elegans sex-determining protein, FEM-1, is a caspase substrate that mediates apoptosis.

P25870	CLH_DICDI	Clathrin heavy chain	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

Q96GW9	SYMM_HUMAN	Methionyl-tRNA synthetase, mitochondrial	15274629	Characterization of the human mitochondrial methionyl-tRNA synthetase.

Q9C0Z1	YKM1_SCHPO	Uncharacterized transcriptional regulatory protein PB24D3.01	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P0AEI4	RIMO_ECOLI	Ribosomal protein S12 methylthiotransferase rimO	18252828	RimO, a MiaB-like enzyme, methylthiolates the universally conserved Asp88 residue of ribosomal protein S12 in Escherichia coli.

Q9NQT8	KI13B_HUMAN	Kinesin-like protein KIF13B	10859302	GAKIN, a novel kinesin-like protein associates with the human homologue of the Drosophila discs large tumor suppressor in T lymphocytes.

P35492	HUTH_MOUSE	Histidine ammonia-lyase	8486363	Identification of the mutation in murine histidinemia (his) and genetic mapping of the murine histidase locus (Hal) on chromosome 10.

Q8WQG9	JNK1_CAEEL	Stress-activated protein kinase jnk-1	10393177	A Caenorhabditis elegans JNK signal transduction pathway regulates coordinated movement via type-D GABAergic motor neurons.

Q12132	USV1_YEAST	Nutrient and stress factor 1	18667581	Nsf1/Ypl230w participates in transcriptional activation during non- fermentative growth and in response to salt stress in Saccharomyces cerevisiae.

Q09892	HOG1_SCHPO	Mitogen-activated protein kinase sty1	8649397	Activation and regulation of the Spc1 stress-activated protein kinase in Schizosaccharomyces pombe.

Q9UT31	MU130_SCHPO	Meiotically up-regulated gene 130 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P30775	RF1M_YEAST	Peptide chain release factor 1, mitochondrial	1475194	The yeast nuclear gene MRF1 encodes a mitochondrial peptide chain release factor and cures several mitochondrial RNA splicing defects.

P40056	GET2_YEAST	Golgi to ER traffic protein 2	10929718	Functional discovery via a compendium of expression profiles.

Q9FYE2	PKS4_ARATH	Protein PHYTOCHROME KINASE SUBSTRATE 4	18390804	PHYTOCHROME KINASE SUBSTRATE4 modulates phytochrome-mediated control of hypocotyl growth orientation.

Q9Y222	DMTF1_HUMAN	Cyclin-D-binding Myb-like transcription factor 1	10095122	Cloning and chromosomal localization of the gene encoding human cyclin D-binding Myb-like protein (hDMP1).

P35700	PRDX1_MOUSE	Peroxiredoxin-1	8360158	Cloning and characterization of a 23-kDa stress-induced mouse peritoneal macrophage protein.

P42286	THR_DROME	Protein three rows	12231632	Proteolytic cleavage of the THR subunit during anaphase limits Drosophila separase function.

P40554	URM1_YEAST	Ubiquitin-related modifier 1	14562095	Global analysis of protein localization in budding yeast.

Q9ZNR6	PDX12_ARATH	Probable pyridoxal biosynthesis protein PDX1.2	16157873	Vitamin B6 biosynthesis in higher plants.

O35303	DNM1L_RAT	Dynamin-1-like protein	12499366	Dynamin-like protein 1 is involved in peroxisomal fission.

Q99988	GDF15_HUMAN	Growth/differentiation factor 15	9326641	MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily.

Q03954	SPC19_YEAST	DASH complex subunit SPC19	15664196	Formation of a dynamic kinetochore-microtubule interface through assembly of the Dam1 ring complex.

P14314	GLU2B_HUMAN	Glucosidase 2 subunit beta	2793184	Isolation of cDNAs encoding a substrate for protein kinase C: nucleotide sequence and chromosomal mapping of the gene for a human 80K protein.

Q96S52	PIGS_HUMAN	GPI transamidase component PIG-S	11483512	PIG-S and PIG-T, essential for GPI anchor attachment to proteins, form a complex with GAA1 and GPI8.

Q96I15	SCLY_HUMAN	Selenocysteine lyase	10692412	cDNA cloning, purification, and characterization of mouse liver selenocysteine lyase. Candidate for selenium delivery protein in selenoprotein synthesis.

Q9WV48	SHAN1_RAT	SH3 and multiple ankyrin repeat domains protein 1	10551867	Somatostatin receptor interacting protein defines a novel family of multidomain proteins present in human and rodent brain.

Q86UE4	LYRIC_HUMAN	Protein LYRIC	16452207	Activation of the nuclear factor kappaB pathway by astrocyte elevated gene-1: implications for tumor progression and metastasis.

P51884	LUM_HUMAN	Lumican	7665616	The human lumican gene. Organization, chromosomal location, and expression in articular cartilage.

Q91903	ELAV2_XENLA	ELAV-like protein 2	10470646	Misexpression of the RNA-binding protein ELRB in Xenopus presumptive neurectoderm induces proliferation arrest and programmed cell death.

Q12248	DAD1_YEAST	DASH complex subunit DAD1	15640796	The yeast DASH complex forms closed rings on microtubules.

Q9LMK7	RBP1A_ARATH	Ran-binding protein 1 homolog a	9025305	Characterization of proteins that interact with the GTP-bound form of the regulatory GTPase Ran in Arabidopsis.

Q9UBZ9	REV1_HUMAN	DNA repair protein REV1	10536157	The human REV1 gene codes for a DNA template-dependent dCMP transferase.

Q9FM79	PME62_ARATH	Pectinesterase QRT1	9744097	Tetrad pollen formation in quartet mutants of Arabidopsis thaliana is associated with persistence of pectic polysaccharides of the pollen mother cell wall.

O02372	OB76A_DROME	General odorant-binding protein lush	15664171	Drosophila OBP LUSH is required for activity of pheromone-sensitive neurons.

Q54WR9	GLNA3_DICDI	Type-3 glutamine synthetase	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P04797	G3P_RAT	Glyceraldehyde-3-phosphate dehydrogenase	10424669	Over-expression of GAPDH induces apoptosis in COS-7 cells transfected with cloned GAPDH cDNAs.

P62263	RS14_HUMAN	40S ribosomal protein S14	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

Q93009	UBP7_HUMAN	Ubiquitin carboxyl-terminal hydrolase 7	11923872	Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization.

P35568	IRS1_HUMAN	Insulin receptor substrate 1	7537849	Phosphotyrosine-dependent interaction of SHC and insulin receptor substrate 1 with the NPEY motif of the insulin receptor via a novel non-SH2 domain.

Q9P805	DCP1_SCHPO	mRNA-decapping enzyme subunit 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q06328	YD352_YEAST	Vacuolar integral membrane protein YDR352W	14562095	Global analysis of protein localization in budding yeast.

Q9USP3	YQ24_SCHPO	Uncharacterized protein C11E10.04, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P01702	LV104_HUMAN	Ig lambda chain V-I region NIG-64	6404900	Comparative studies on the structure of the light chains of human immunoglobulins. IV. Assignment of a subsubgroup.

P35169	TOR1_YEAST	Serine/threonine-protein kinase TOR1	10973982	HEAT repeats mediate plasma membrane localization of Tor2p in yeast.

Q99NB8	UBQL4_MOUSE	Ubiquilin-4	11162551	Molecular cloning of a novel ubiquitin-like protein, UBIN, that binds to ER targeting signal sequences.

Q8LAD0	PDX2_ARATH	Pyridoxal biosynthesis protein PDX2	16766694	Analysis of the Arabidopsis rsr4-1/pdx1-3 mutant reveals the critical function of the PDX1 protein family in metabolism, development, and vitamin B6 biosynthesis.

O74854	POF6_SCHPO	F-box protein pof6	12511573	Skp1 and the F-box protein Pof6 are essential for cell separation in fission yeast.

Q14999	CUL7_HUMAN	Cullin-7	17298945	The conserved CPH domains of Cul7 and PARC are protein-protein interaction modules that bind the tetramerization domain of p53.

Q63120	MRP2_RAT	Canalicular multispecific organic anion transporter 1	8599091	Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene.

Q03323	SDC1_YEAST	COMPASS component SDC1	11805083	COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression.

Q9W157	BRCA2_DROME	Breast cancer type 2 susceptibility protein homolog	17822964	Functional analysis of Drosophila melanogaster BRCA2 in DNA repair.

P69434	PGAA_ECOLI	Poly-beta-1,6-N-acetyl-D-glucosamine export protein	18359807	Roles of pgaABCD genes in synthesis, modification, and export of the Escherichia coli biofilm adhesin poly-beta-1,6-N-acetyl-D- glucosamine.

Q9NZW5	MPP6_HUMAN	MAGUK p55 subfamily member 6	11311936	VAM-1: a new member of the MAGUK family binds to human Veli-1 through a conserved domain.

Q54RV9	SGPL_DICDI	Sphingosine-1-phosphate lyase	15476260	Sphingosine-1-phosphate plays a role in the suppression of lateral pseudopod formation during Dictyostelium discoideum cell migration and chemotaxis.

Q8K0T0	RTN1_MOUSE	Reticulon-1	12036513	Mosaic development of the olfactory cortex with Pax6-dependent and -independent components.

P11055	MYH3_HUMAN	Myosin-3	2771643	Expression and DNA sequence analysis of a human embryonic skeletal muscle myosin heavy chain gene.

P08551	NFL_MOUSE	Neurofilament light polypeptide	16236762	RNA-binding protein is involved in aggregation of light neurofilament protein and is implicated in the pathogenesis of motor neuron degeneration.

Q63028	ADDA_RAT	Alpha-adducin	8624703	Spatial and sub-cellular localization of the membrane cytoskeleton- associated protein alpha-adducin in the rat brain.

Q9Y336	SIGL9_HUMAN	Sialic acid-binding Ig-like lectin 9	10801860	Cloning, characterization, and phylogenetic analysis of siglec-9, a new member of the CD33-related group of siglecs. Evidence for co- evolution with sialic acid synthesis pathways.

Q86UW1	OSTA_HUMAN	Organic solute transporter subunit alpha	12719432	Functional complementation between a novel mammalian polygenic transport complex and an evolutionarily ancient organic solute transporter, OSTalpha-OSTbeta.

Q9PUK8	FZD7A_XENLA	Frizzled-7-A	15272309	Xenopus paraxial protocadherin has signaling functions and is involved in tissue separation.

Q75JL2	RECAM_DICDI	Mitochondrial DNA repair protein recA homolog	15084313	A homolog of Escherichia coli RecA in mitochondria of the cellular slime mold Dictyostelium discoideum.

P33203	PRP40_YEAST	Pre-mRNA-processing protein PRP40	8622699	Identification of Prp40, a novel essential yeast splicing factor associated with the U1 small nuclear ribonucleoprotein particle.

P14324	FPPS_HUMAN	Farnesyl pyrophosphate synthase	2690933	Cloning, analysis, and bacterial expression of human farnesyl pyrophosphate synthetase and its regulation in Hep G2 cells.

Q8LAH7	OPR1_ARATH	12-oxophytodienoate reductase 1	10872231	12-Oxophytodienoate reductase 3 (OPR3) is the isoenzyme involved in jasmonate biosynthesis.

Q9GZU1	MCLN1_HUMAN	Mucolipin-1	11030752	Mucolipidosis type IV is caused by mutations in a gene encoding a novel transient receptor potential channel.

P21711	MIX1_XENLA	Homeobox protein Mix.1	12710967	Molecular link in the sequential induction of the Spemann organizer: direct activation of the cerberus gene by Xlim-1, Xotx2, Mix.1, and Siamois, immediately downstream from Nodal and Wnt signaling.

P25644	PAT1_YEAST	DNA topoisomerase 2-associated protein PAT1	8972867	Pat1: a topoisomerase II-associated protein required for faithful chromosome transmission in Saccharomyces cerevisiae.

Q9JLS4	SFRP4_RAT	Secreted frizzled-related protein 4	12960062	Expression and localization of secreted frizzled-related protein-4 in the rodent ovary: evidence for selective up-regulation in luteinized granulosa cells.

P55853	SUMO_CAEEL	Small ubiquitin-related modifier	15689373	Sumoylation of LIN-1 promotes transcriptional repression and inhibition of vulval cell fates.

P50402	EMD_HUMAN	Emerin	15328537	Emerin caps the pointed end of actin filaments: evidence for an actin cortical network at the nuclear inner membrane.

P43583	BLM10_YEAST	Proteasome activator BLM10	12973301	Blm3 is part of nascent proteasomes and is involved in a late stage of nuclear proteasome assembly.

P15151	PVR_HUMAN	Poliovirus receptor	19011627	The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.

Q9Z1W6	LYRIC_RAT	Protein LYRIC	15383321	Identification of a novel protein, LYRIC, localized to tight junctions of polarized epithelial cells.

P32068	TRPE_ARATH	Anthranilate synthase component I-1, chloroplastic	1392592	Two anthranilate synthase genes in Arabidopsis: defense-related regulation of the tryptophan pathway.

Q08923	CTI6_YEAST	Histone deacetylase complex subunit CTI6	16314178	Stable incorporation of sequence specific repressors Ash1 and Ume6 into the Rpd3L complex.

Q9SE45	ANXD3_ARATH	Annexin D3	16531057	Expression profiling of the Arabidopsis annexin gene family during germination, de-etiolation and abiotic stress.

Q61234	SNTA1_MOUSE	Alpha-1-syntrophin	9214383	Differential association of syntrophin pairs with the dystrophin complex.

O74529	YJ48_SCHPO	Uncharacterized methyltransferase C70.08c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P05434	CATR_CHLRE	Caltractin	16317001	Structure of the N-terminal calcium sensor domain of centrin reveals the biochemical basis for domain-specific function.

Q9FKA5	Y5957_ARATH	Uncharacterized protein At5g39570	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

Q8CBD1	NRIP1_MOUSE	Nuclear receptor-interacting protein 1	15919748	Multiple signaling defects in the absence of RIP140 impair both cumulus expansion and follicle rupture.

Q99PP2	ZN318_MOUSE	Zinc finger protein 318	12589823	Molecular cloning and characteristics of a novel zinc finger protein and its splice variant whose transcripts are expressed during spermatogenesis.

P32333	MOT1_YEAST	TATA-binding protein-associated factor MOT1	11880621	Mot1 activates and represses transcription by direct, ATPase- dependent mechanisms.

Q9UHC3	ACCN3_HUMAN	Amiloride-sensitive cation channel 3	9744806	Identification, functional expression and chromosomal localisation of a sustained human proton-gated cation channel.

Q39233	SYP21_ARATH	Syntaxin-21	7638178	An Arabidopsis syntaxin homologue isolated by functional complementation of a yeast pep12 mutant.

Q9WVA3	BUB3_MOUSE	Mitotic checkpoint protein BUB3	19888327	Bub3 is a spindle assembly checkpoint protein regulating chromosome segregation during mouse oocyte meiosis.

O00139	KIF2A_HUMAN	Kinesin-like protein KIF2A	9177777	Identification of a novel human kinesin-related gene (HK2) by the cDNA differential display technique.

P03886	NU1M_HUMAN	NADH-ubiquinone oxidoreductase chain 1	3921850	Six unidentified reading frames of human mitochondrial DNA encode components of the respiratory-chain NADH dehydrogenase.

P36007	SRY1_YEAST	Threo-3-hydroxyaspartate ammonia-lyase	12951240	Serine racemase homologue of Saccharomyces cerevisiae has L-threo-3- hydroxyaspartate dehydratase activity.

Q09154	UCRI_SCHPO	Cytochrome b-c1 complex subunit Rieske, mitochondrial	8663290	Heterologous complementation of a Rieske iron-sulfur protein- deficient Saccharomyces cerevisiae by the Rip1 gene of Schizosaccharomyces pombe.

O43916	CHST1_HUMAN	Carbohydrate sulfotransferase 1	9405439	Molecular cloning and characterization of human keratan sulfate Gal- 6-sulfotransferase.

P56178	DLX5_HUMAN	Homeobox protein DLX-5	7907794	Cloning and characterization of two members of the vertebrate Dlx gene family.

Q9Y6J9	TAF6L_HUMAN	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L	11564863	Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage- binding factors in vivo.

Q16515	ACCN1_HUMAN	Amiloride-sensitive cation channel 1, neuronal	8626462	Cloning and expression of a novel human brain Na+ channel.

Q8CFA7	KLF17_MOUSE	Krueppel-like factor 17	12351194	Identification of Zfp393, a germ cell-specific gene encoding a novel zinc finger protein.

P03915	NU5M_HUMAN	NADH-ubiquinone oxidoreductase chain 5	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

Q58576	PAN_METJA	Proteasome-activating nucleotidase	19481528	Mechanism of substrate unfolding and translocation by the regulatory particle of the proteasome from Methanocaldococcus jannaschii.

Q1ECF1	PYL7_ARATH	Abscisic acid receptor PYL7	19874541	PYR/PYL/RCAR family members are major in-vivo ABI1 protein phosphatase 2C-interacting proteins in Arabidopsis.

Q5YDB6	CPL1_ARATH	RNA polymerase II C-terminal domain phosphatase-like 1	18541146	The C-terminal region (640-967) of Arabidopsis CPL1 interacts with the abiotic stress- and ABA-responsive transcription factors.

O42882	YFQ5_SCHPO	Uncharacterized protein C8E11.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q7DNA1	CHI2_ORYSJ	Chitinase 2	18211919	Role of the loop structure of the catalytic domain in rice class I chitinase.

P97346	NXN_MOUSE	Nucleoredoxin	9119370	Cloning and characterization of the nucleoredoxin gene that encodes a novel nuclear protein related to thioredoxin.

P98083	SHC1_MOUSE	SHC-transforming protein 1	10068665	A novel spliced form of SH2-containing inositol phosphatase is expressed during myeloid development.

Q10045	UNC50_CAEEL	Protein unc-50	17853888	Regulation of nicotinic receptor trafficking by the transmembrane Golgi protein UNC-50.

P46100	ATRX_HUMAN	Transcriptional regulator ATRX	10570185	Localization of a putative transcriptional regulator (ATRX) at pericentromeric heterochromatin and the short arms of acrocentric chromosomes.

Q8WTD4	DEF_GLOMM	Defensin-A	11592981	Tsetse immune responses and trypanosome transmission: implications for the development of tsetse-based strategies to reduce trypanosomiasis.

P47061	VPS53_YEAST	Vacuolar protein sorting-associated protein 53	12686613	Vps51p mediates the association of the GARP (Vps52/53/54) complex with the late Golgi t-SNARE Tlg1p.

P25342	CDC10_YEAST	Cell division control protein 10	12665577	Molecular dissection of a yeast septin: distinct domains are required for septin interaction, localization, and function.

Q12083	MLH3_YEAST	DNA mismatch repair protein MLH3	10570173	Functional specificity of MutL homologs in yeast: evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction.

P34233	ASH1_YEAST	Transcriptional regulatory protein ASH1	16314178	Stable incorporation of sequence specific repressors Ash1 and Ume6 into the Rpd3L complex.

Q6PEM8	PCFT_MOUSE	Proton-coupled folate transporter	16143108	Identification of an intestinal heme transporter.

O15151	MDM4_HUMAN	Protein Mdm4	19838211	MdmX is a substrate for the deubiquitinating enzyme USP2a.

Q8NE71	ABCF1_HUMAN	ATP-binding cassette sub-family F member 1	9790762	ABC50, a novel human ATP-binding cassette protein found in tumor necrosis factor-alpha-stimulated synoviocytes.

P77202	DSBG_ECOLI	Thiol:disulfide interchange protein DsbG	9383195	A new Escherichia coli gene, dsbG, encodes a periplasmic protein involved in disulphide bond formation, required for recycling DsbA/DsbB and DsbC redox proteins.

Q15622	OR7A5_HUMAN	Olfactory receptor 7A5	9119360	Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species.

Q10070	MDM31_SCHPO	Mitochondrial distribution and morphology protein 31	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9ZUH4	MYRS1_ARATH	Myrcene/ocimene synthase 1, chloroplastic	16021335	Expression profiling reveals COI1 to be a key regulator of genes involved in wound- and methyl jasmonate-induced secondary metabolism, defence, and hormone interactions.

Q10337	BRC1_SCHPO	BRCT-containing protein 1	10473635	Rad18 is required for DNA repair and checkpoint responses in fission yeast.

Q9FH76	ABAH3_ARATH	Abscisic acid 8'-hydroxylase 3	16623881	CYP707A3, a major ABA 8'-hydroxylase involved in dehydration and rehydration response in Arabidopsis thaliana.

Q03519	TAP2_HUMAN	Antigen peptide transporter 2	8955196	Multiple regions of the transporter associated with antigen processing (TAP) contribute to its peptide binding site.

O08665	SEM3A_MOUSE	Semaphorin-3A	7748561	Murine semaphorin D/collapsin is a member of a diverse gene family and creates domains inhibitory for axonal extension.

Q9USJ9	MNP1_SCHPO	60 ribosomal protein L12, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P63142	KCNA2_RAT	Potassium voltage-gated channel subfamily A member 2	7477295	Clustering of Shaker-type K+ channels by interaction with a family of membrane-associated guanylate kinases.

Q9UK55	ZPI_HUMAN	Protein Z-dependent protease inhibitor	10460162	The protein Z-dependent protease inhibitor is a serpin.

Q811T9	DISC1_MOUSE	Disrupted in schizophrenia 1 homolog	17825401	Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain.

O13941	YEPB_SCHPO	Uncharacterized beta-glucan synthesis-associated protein C23H3.11c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q0WV12	ANL2_ARATH	Homeobox-leucine zipper protein ANTHOCYANINLESS 2	10402424	ANTHOCYANINLESS2, a homeobox gene affecting anthocyanin distribution and root development in Arabidopsis.

Q8W1X2	PDXK_ARATH	Pyridoxal kinase	12068103	SOS4, a pyridoxal kinase gene, is required for root hair development in Arabidopsis.

Q12882	DPYD_HUMAN	Dihydropyrimidine dehydrogenase [NADP+]	1512248	Purification and characterization of dihydropyrimidine dehydrogenase from human liver.

Q09909	CWF19_SCHPO	Pre-mRNA-splicing factor cwf19	11884590	Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

P42088	LEC_BOWMI	Lectin	2925660	Bowringia milbraedii agglutinin. Specificity of binding to early processing intermediates of asparagine-linked oligosaccharide and use as a marker of endoplasmic reticulum glycoproteins.

P10823	GPA2_YEAST	Guanine nucleotide-binding protein alpha-2 subunit	2830616	Isolation of a second yeast Saccharomyces cerevisiae gene (GPA2) coding for guanine nucleotide-binding regulatory protein: studies on its structure and possible functions.

P46654	RSSA2_YEAST	40S ribosomal protein S0-B	8626693	Yeast proteins related to the p40/laminin receptor precursor are essential components of the 40 S ribosomal subunit.

Q10103	CHP1_SCHPO	Chromo domain-containing protein 1	9722643	The fission yeast chromo domain encoding gene chp1(+) is required for chromosome segregation and shows a genetic interaction with alpha- tubulin.

O94365	UTP15_SCHPO	U3 small nucleolar RNA-associated protein 15	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P37268	FDFT_HUMAN	Squalene synthase	8474436	Conservation between human and fungal squalene synthetases: similarities in structure, function, and regulation.

Q8UW74	HE71A_XENLA	Transcription factor HES-7.1-A	11731236	Early patterning of the prospective midbrain-hindbrain boundary by the HES-related gene XHR1 in Xenopus embryos.

Q54XG7	DIMA_DICDI	Basic-leucine zipper transcription factor A	14729573	A bZIP/bRLZ transcription factor required for DIF signaling in Dictyostelium.

Q02085	SNAI1_MOUSE	Zinc finger protein SNAI1	12832491	Phosphorylation regulates the subcellular location and activity of the snail transcriptional repressor.

Q969U7	PSMG2_HUMAN	Proteasome assembly chaperone 2	16251969	A heterodimeric complex that promotes the assembly of mammalian 20S proteasomes.

Q9NR64	KLHL1_HUMAN	Kelch-like protein 1	10888605	The SCA8 transcript is an antisense RNA to a brain-specific transcript encoding a novel actin-binding protein (KLHL1).

Q07830	GPI13_YEAST	GPI ethanolamine phosphate transferase 3	12441642	Genetic characterization of genes encoding enzymes catalyzing addition of phospho-ethanolamine to the glycosylphosphatidylinositol anchor in Saccharomyces cerevisiae.

P55868	AG1_XENLA	Anterior gradient protein 1	9533957	Anterior specification of embryonic ectoderm: the role of the Xenopus cement gland-specific gene XAG-2.

Q93243	NAS37_CAEEL	Zinc metalloproteinase nas-37	15539494	A conserved metalloprotease mediates ecdysis in Caenorhabditis elegans.

Q12341	HAT1_YEAST	Histone acetyltransferase type B catalytic subunit	7559580	Identification of a gene encoding a yeast histone H4 acetyltransferase.

Q00195	CNGA2_RAT	Cyclic nucleotide-gated olfactory channel	1697649	Primary structure and functional expression of a cyclic nucleotide- activated channel from olfactory neurons.

P25445	TNR6_HUMAN	Tumor necrosis factor receptor superfamily member 6	7538908	RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death.

O00255	MEN1_HUMAN	Menin	15199122	Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression.

P46995	SET2_YEAST	Histone-lysine N-methyltransferase, H3 lysine-36 specific	12736296	The histone 3 lysine 36 methyltransferase, SET2, is involved in transcriptional elongation.

Q9FGR0	CPSF1_ARATH	Cleavage and polyadenylation specificity factor subunit 1	16897494	The 73 kD subunit of the cleavage and polyadenylation specificity factor (CPSF) complex affects reproductive development in Arabidopsis.

Q9NIW4	TRA2_CAERE	Sex-determining transformer protein 2	12477393	Rapid coevolution of the nematode sex-determining genes fem-3 and tra-2.

Q13227	GPS2_HUMAN	G protein pathway suppressor 2	11931768	The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2.

Q8K3Y3	LN28A_MOUSE	Protein lin-28 homolog A	18292307	Selective blockade of microRNA processing by Lin28.

Q80WD1	R4RL2_RAT	Reticulon-4 receptor-like 2	12694398	Characterization of two novel proteins, NgRH1 and NgRH2, structurally and biochemically homologous to the Nogo-66 receptor.

Q9UTD7	RRP15_SCHPO	Ribosomal RNA-processing protein 15	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P27348	1433T_HUMAN	14-3-3 protein theta	19172738	Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein.

Q03407	PKH1_YEAST	Serine/threonine-protein kinase PKH1	10074427	Functional counterparts of mammalian protein kinases PDK1 and SGK in budding yeast.

Q23976	KU70_DROME	ATP-dependent DNA helicase 2 subunit 1	7809101	A Drosophila protein homologous to the human p70 Ku autoimmune antigen interacts with the P transposable element inverted repeats.

P45202	YBAK_HAEIN	Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase ybaK	14530268	An isolated class II aminoacyl-tRNA synthetase insertion domain is functional in amino acid editing.

P42951	LSB6_YEAST	Phosphatidylinositol 4-kinase LSB6	12361950	The Saccharomyces cerevisiae LSB6 gene encodes phosphatidylinositol 4-kinase activity.

P23293	BUR1_YEAST	Serine/threonine-protein kinase BUR1	10982824	BUR1 and BUR2 encode a divergent cyclin-dependent kinase-cyclin complex important for transcription in vivo.

O54949	NLK_MOUSE	Serine/threonine-protein kinase NLK	14720327	Nemo-like kinase suppresses a wide range of transcription factors, including nuclear factor-kappaB.

P54003	SUR7_YEAST	Protein SUR7	11784867	The Sur7p family defines novel cortical domains in Saccharomyces cerevisiae, affects sphingolipid metabolism, and is involved in sporulation.

P53313	SDA1_YEAST	Protein SDA1	10704371	The Saccharomyces cerevisiae SDA1 gene is required for actin cytoskeleton organization and cell cycle progression.

O95996	APC2_HUMAN	Adenomatous polyposis coli protein 2	9823329	Identification of a brain-specific APC homologue, APCL, and its interaction with beta-catenin.

O13641	YGWG_SCHPO	Uncharacterized protein C8D2.16c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P56937	DHB7_HUMAN	3-keto-steroid reductase	10544267	Determination of cDNA, gene structure and chromosomal localization of the novel human 17beta-hydroxysteroid dehydrogenase type 7.

P43120	HHEX_MOUSE	Hematopoietically-expressed homeobox protein Hhex	16936074	Hex acts with beta-catenin to regulate anteroposterior patterning via a Groucho-related co-repressor and Nodal.

Q9I8N6	CSF1R_DANRE	Macrophage colony-stimulating factor 1 receptor	10862741	An orthologue of the kit-related gene fms is required for development of neural crest-derived xanthophores and a subpopulation of adult melanocytes in the zebrafish, Danio rerio.

Q9QYM8	CENPH_MOUSE	Centromere protein H	10488063	Characterization of a novel kinetochore protein, CENP-H.

Q10362	SET3_SCHPO	SET domain-containing protein 3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P25847	MSH2_YEAST	DNA mismatch repair protein MSH2	9256462	Role of Saccharomyces cerevisiae Msh2 and Msh3 repair proteins in double-strand break-induced recombination.

Q8MVS5	GLT35_DROME	Polypeptide N-acetylgalactosaminyltransferase 35A	11925450	Functional conservation of subfamilies of putative UDP-N- acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferases in Drosophila, Caenorhabditis elegans, and mammals. One subfamily composed of l(2)35Aa is essential in Drosophila.

O80983	FTSH4_ARATH	ATP-dependent zinc metalloprotease FTSH 4, mitochondrial	14630971	Coordinated regulation and complex formation of yellow variegated1 and yellow variegated2, chloroplastic FtsH metalloproteases involved in the repair cycle of photosystem II in Arabidopsis thylakoid membranes.

Q8JGN5	BI51A_XENLA	Baculoviral IAP repeat-containing protein 5.1-A	15260989	The chromosomal passenger complex is required for chromatin-induced microtubule stabilization and spindle assembly.

Q9LZU4	CRK4_ARATH	Cysteine-rich receptor-like protein kinase 4	15604743	Activation of hypersensitive cell death by pathogen-induced receptor- like protein kinases from Arabidopsis.

O14286	ATM1_SCHPO	Iron-sulfur clusters transporter atm1, mitochondrial	16306692	Mitochondrial ABC transporter Atm1p is required for protection against oxidative stress and vacuolar functions in Schizosaccharomyces pombe.

Q91X05	PODO_MOUSE	Podocin	11733557	Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin.

Q10953	WRM1_CAEEL	Armadillo repeat-containing protein wrm-1	15066285	Phosphorylation by the beta-catenin/MAPK complex promotes 14-3-3- mediated nuclear export of TCF/POP-1 in signal-responsive cells in C. elegans.

Q39191	WAK1_ARATH	Wall-associated receptor kinase 1	11335717	Interaction of the Arabidopsis receptor protein kinase Wak1 with a glycine-rich protein, AtGRP-3.

Q9UBL3	ASH2L_HUMAN	Set1/Ash2 histone methyltransferase complex subunit ASH2	10393421	Cloning and characterization of ASH2L and ash2l, human and mouse homologs of the Drosophila ash2 gene.

Q9UN71	PCDGG_HUMAN	Protocadherin gamma-B4	9199196	Multiple cadherins are expressed in human fibroblasts.

Q9HCG7	GBA2_HUMAN	Non-lysosomal glucosylceramidase	17105727	Identification of the non-lysosomal glucosylceramidase as beta- glucosidase 2.

Q9P7R5	GFH1_SCHPO	Gamma-tubulin complex component gfh1	15004232	Identification and characterization of two novel proteins affecting fission yeast gamma-tubulin complex function.

P94040	GL31_ARATH	Germin-like protein subfamily 3 member 1	10987552	Arabidopsis thaliana germin-like proteins: common and specific features point to a variety of functions.

Q24008	INAD_DROME	Inactivation-no-after-potential D protein	11342563	The second PDZ domain of INAD is a type I domain involved in binding to eye protein kinase C. Mutational analysis and naturally occurring variants.

P54609	CD48A_ARATH	Cell division control protein 48 homolog A	17693538	In vivo hexamerization and characterization of the Arabidopsis AAA ATPase CDC48A complex using forster resonance energy transfer- fluorescence lifetime imaging microscopy and fluorescence correlation spectroscopy.

O54829	RGS7_MOUSE	Regulator of G-protein signaling 7	15897264	Palmitoylation regulates plasma membrane-nuclear shuttling of R7BP, a novel membrane anchor for the RGS7 family.

O09106	HDAC1_MOUSE	Histone deacetylase 1	14645126	Atrophin 2 recruits histone deacetylase and is required for the function of multiple signaling centers during mouse embryogenesis.

O95476	DULRD_HUMAN	Serine/threonine-protein phosphatase dullard	17420445	A conserved phosphatase cascade that regulates nuclear membrane biogenesis.

O75396	SC22B_HUMAN	Vesicle-trafficking protein SEC22b	15272311	Involvement of BNIP1 in apoptosis and endoplasmic reticulum membrane fusion.

O80725	AB4B_ARATH	ABC transporter B family member 4	16243904	PGP4, an ATP binding cassette P-glycoprotein, catalyzes auxin transport in Arabidopsis thaliana roots.

Q2L4W6	SPO5_SCHPO	Sporulation-specific protein 5	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UKJ1	PILRA_HUMAN	Paired immunoglobulin-like type 2 receptor alpha	18358807	PILRalpha is a herpes simplex virus-1 entry coreceptor that associates with glycoprotein B.

Q9PVX8	STA31_XENLA	Signal transducer and activator of transcription 3.1	15004007	Role of the TAK1-NLK-STAT3 pathway in TGF-beta-mediated mesoderm induction.

P24887	NU1M_CAEEL	NADH-ubiquinone oxidoreductase chain 1	1551572	The mitochondrial genomes of two nematodes, Caenorhabditis elegans and Ascaris suum.

Q9VQ89	MIO_DROME	WD repeat-containing protein mio	14973288	missing oocyte encodes a highly conserved nuclear protein required for the maintenance of the meiotic cycle and oocyte identity in Drosophila.

P47979	ZFS1_SCHPO	Zinc finger protein zfs1	8534915	Schizosaccharomyces pombe zfs1+ encoding a zinc-finger protein functions in the mating pheromone recognition pathway.

P49739	MCM3M_XENLA	Maternal DNA replication licensing factor mcm3	9214646	The RLF-M component of the replication licensing system forms complexes containing all six MCM/P1 polypeptides.

P40087	DDI1_YEAST	DNA damage-inducible protein 1	12051757	Ubiquitin-like proteins and Rpn10 play cooperative roles in ubiquitin-dependent proteolysis.

Q7TNJ4	AMGO2_RAT	Amphoterin-induced protein 2	12843293	Alivin 1, a novel neuronal activity-dependent gene, inhibits apoptosis and promotes survival of cerebellar granule neurons.

O70552	BTG4_MOUSE	Protein BTG4	10995567	Cloning of PC3B, a novel member of the PC3/BTG/TOB family of growth inhibitory genes, highly expressed in the olfactory epithelium.

O75626	PRDM1_HUMAN	PR domain zinc finger protein 1	1851123	Identification and characterization of a novel repressor of beta- interferon gene expression.

Q16630	CPSF6_HUMAN	Cleavage and polyadenylation specificity factor subunit 6	14561889	Association of polyadenylation cleavage factor I with U1 snRNP.

P32336	NUD1_YEAST	Protein NUD1	11973299	Ady3p links spindle pole body function to spore wall synthesis in Saccharomyces cerevisiae.

Q7KVA1	XYLT_DROME	Xylosyltransferase oxt	11929872	Functional expression of Drosophila melanogaster peptide O- xylosyltransferase, the key enzyme for proteoglycan chain initiation and member of the core 2/I N-acetylglucosaminyltransferase family.

P54987	IRG1_MOUSE	Immune-responsive gene 1 protein	7721348	Cloning and analysis of gene regulation of a novel LPS-inducible cDNA.

P01599	KV107_HUMAN	Ig kappa chain V-I region Gal	4215718	The primary structure of a monoclonal IgM-immunoglobulin (macroglobulin Gal.), I. The amino acid sequence of the L-chain of kappa-type, subgroup I.

P53008	CWH41_YEAST	Mannosyl-oligosaccharide glucosidase	9363442	The yeast CWH41 gene encodes glucosidase I.

Q9NNW7	TRXR2_HUMAN	Thioredoxin reductase 2, mitochondrial	10215850	Human mitochondrial thioredoxin reductase: cDNA cloning, expression and genomic organization.

Q7M6Y3	PICA_MOUSE	Phosphatidylinositol-binding clathrin assembly protein	12832620	Mutations in the clathrin-assembly gene Picalm are responsible for the hematopoietic and iron metabolism abnormalities in fit1 mice.

P85109	VSP1_AGKHB	Thrombin-like enzyme kangshuanmei	11491462	Characterization of a thrombin-like serine protease, Kangshuanmei, isolated from the venom of a Chinese snake, Agkistrodon halys brevicaudus stejneger.

Q94527	NFKB1_DROME	Nuclear factor NF-kappa-B p110 subunit	8816802	Origins of immunity: Relish, a compound Rel-like gene in the antibacterial defense of Drosophila.

P46955	NCA3_YEAST	Protein NCA3, mitochondrial	7586026	NCA3, a nuclear gene involved in the mitochondrial expression of subunits 6 and 8 of the Fo-F1 ATP synthase of S. cerevisiae.

P49333	ETR1_ARATH	Ethylene receptor 1	18577522	Heteromeric interactions among ethylene receptors mediate signaling in Arabidopsis.

A0QZ48	PUP_MYCS2	Prokaryotic ubiquitin-like protein Pup	19028679	Proteasomal protein degradation in mycobacteria is dependent upon a prokaryotic ubiquitin-like protein.

Q8BGN3	ENPP6_MOUSE	Ectonucleotide pyrophosphatase/phosphodiesterase family member 6	15788404	Biochemical and molecular characterization of a novel choline- specific glycerophosphodiester phosphodiesterase belonging to the nucleotide pyrophosphatase/phosphodiesterase family.

P53909	ADA_YEAST	Adenosine deaminase	14562095	Global analysis of protein localization in budding yeast.

Q9NVV9	THAP1_HUMAN	THAP domain-containing protein 1	15863623	The THAP domain of THAP1 is a large C2CH module with zinc-dependent sequence-specific DNA-binding activity.

Q9NR28	DBLOH_HUMAN	Diablo homolog, mitochondrial	10972280	Structural and biochemical basis of apoptotic activation by Smac/DIABLO.

Q62315	JARD2_MOUSE	Protein Jumonji	12890668	JUMONJI, a critical factor for cardiac development, functions as a transcriptional repressor.

Q8CG09	MRP1_RAT	Multidrug resistance-associated protein 1	11208926	The multidrug resistance protein MRP1 mediates the release of glutathione disulfide from rat astrocytes during oxidative stress.

P15976	GATA1_HUMAN	Erythroid transcription factor	2104960	Structure and evolution of a human erythroid transcription factor.

Q0VBL6	HIF3A_MOUSE	Hypoxia-inducible factor 3-alpha	9840812	Molecular characterization and chromosomal localization of a third alpha-class hypoxia inducible factor subunit, HIF3alpha.

Q86AS5	PPCE_DICDI	Prolyl endopeptidase	10329620	Loss of a prolyl oligopeptidase confers resistance to lithium by elevation of inositol (1,4,5) trisphosphate.

Q99732	LITAF_HUMAN	Lipopolysaccharide-induced tumor necrosis factor-alpha factor	10200294	A novel lipopolysaccharide-induced transcription factor regulating tumor necrosis factor alpha gene expression: molecular cloning, sequencing, characterization, and chromosomal assignment.

P0A908	MIPA_ECOLI	MltA-interacting protein	10037771	Demonstration of molecular interactions between the murein polymerase PBP1B, the lytic transglycosylase MltA, and the scaffolding protein MipA of Escherichia coli.

Q9FUT3	AB23B_ARATH	ABC transporter B family member 23, mitochondrial	11158531	A mutation of the mitochondrial ABC transporter Sta1 leads to dwarfism and chlorosis in the Arabidopsis mutant starik.

Q9D0P7	PSRC1_MOUSE	Proline/serine-rich coiled-coil protein 1	10618717	Identification of a novel mouse p53 target gene DDA3.

P39008	POP2_YEAST	Poly(A) ribonuclease POP2	10490603	The CCR4 and CAF1 proteins of the CCR4-NOT complex are physically and functionally separated from NOT2, NOT4, and NOT5.

O13907	ACL2_SCHPO	Probable ATP-citrate synthase subunit 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O43283	M3K13_HUMAN	Mitogen-activated protein kinase kinase kinase 13	11163770	Identification and characterization of functional domains in a mixed lineage kinase LZK.

P32454	APE2_YEAST	Aminopeptidase 2, mitochondrial	383482	External and internal forms of yeast aminopeptidase II.

P77258	NEMA_ECOLI	N-ethylmaleimide reductase	9013822	Molecular cloning of the nemA gene encoding N-ethylmaleimide reductase from Escherichia coli.

Q64112	IFIT2_MOUSE	Interferon-induced protein with tetratricopeptide repeats 2	7896268	Structure, chromosome localization, and regulation of expression of the interferon-regulated mouse Ifi54/Ifi56 gene family.

O75969	AKAP3_HUMAN	A-kinase anchor protein 3	10334916	Cloning and characterization of SOB1, a new testis-specific cDNA encoding a human sperm protein probably involved in oocyte recognition.

Q5W7F2	AGD3_ARATH	ADP-ribosylation factor GTPase-activating protein AGD3	10887076	A series of novel mutants of Arabidopsis thaliana that are defective in the formation of continuous vascular network: calling the auxin signal flow canalization hypothesis into question.

P70327	TBX6_MOUSE	T-box transcription factor TBX6	9490412	Three neural tubes in mouse embryos with mutations in the T-box gene Tbx6.

O74809	YGNJ_SCHPO	Uncharacterized protein C2D10.19c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P13601	AL1A7_RAT	Aldehyde dehydrogenase, cytosolic 1	10998257	Rat liver constitutive and phenobarbital-inducible cytosolic aldehyde dehydrogenases are highly homologous proteins that function as distinct isozymes.

Q9P6I6	YHG3_SCHPO	Uncharacterized protein C1198.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8NI51	CTCFL_HUMAN	Transcriptional repressor CTCFL	18765639	BAT3 and SET1A form a complex with CTCFL/BORIS to modulate H3K4 histone dimethylation and gene expression.

P38748	ETP1_YEAST	RING finger protein ETP1	19416103	ETP1/YHL010c is a novel gene needed for the adaptation of Saccharomyces cerevisiae to ethanol.

O74630	ATM_SCHPO	Serine/threonine-protein kinase tel1	15964794	ATM activation and its recruitment to damaged DNA require binding to the C-terminus of Nbs1.

Q9ES52	SHIP1_MOUSE	Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1	11031258	SHIP1, an SH2 domain containing polyinositol-5-phosphatase, regulates migration through two critical tyrosine residues and forms a novel signaling complex with DOK1 and CRKL.

Q9NWB7	IFT57_HUMAN	Intraflagellar transport protein 57 homolog	11788820	Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi.

Q9EQ61	PESC_MOUSE	Pescadillo homolog	11112348	The murine Pes1 gene encodes a nuclear protein containing a BRCT domain.

Q965H3	SOP2_CAEEL	Polycomb protein sop-2	15200961	The C. elegans Polycomb gene sop-2 encodes an RNA binding protein.

P0C7A3	MBOA4_MOUSE	Ghrelin O-acyltransferase	18443287	Ghrelin octanoylation mediated by an orphan lipid transferase.

Q9QZN9	CNR2_RAT	Cannabinoid receptor 2	12084572	Cloning and molecular characterization of the rat CB2 cannabinoid receptor.

O14662	STX16_HUMAN	Syntaxin-16	9587053	Syntaxin-16, a putative Golgi t-SNARE.

Q9FQ04	XRN4_ARATH	5'-3' exoribonuclease 4	16920797	ETHYLENE-INSENSITIVE5 encodes a 5'-->3' exoribonuclease required for regulation of the EIN3-targeting F-box proteins EBF1/2.

Q42403	TRXH3_ARATH	Thioredoxin H3	7777559	Evidence for five divergent thioredoxin h sequences in Arabidopsis thaliana.

O13339	TERT_SCHPO	Telomerase reverse transcriptase	12676088	Telomere maintenance in fission yeast requires an Est1 ortholog.

P49638	TTPA_HUMAN	Alpha-tocopherol transfer protein	7887897	Human alpha-tocopherol transfer protein: cDNA cloning, expression and chromosomal localization.

P32462	ERG24_YEAST	Delta(14)-sterol reductase	1418625	Cloning, sequencing, and disruption of the gene encoding sterol C-14 reductase in Saccharomyces cerevisiae.

Q8VYR7	BOR1_ARATH	Boron transporter 1	20194745	Polar localization and degradation of Arabidopsis boron transporters through distinct trafficking pathways.

P21707	SYT1_RAT	Synaptotagmin-1	8910372	Isoform-specific, calcium-regulated interaction of the synaptic vesicle proteins SV2 and synaptotagmin.

P42845	STB1_YEAST	Protein STB1	14562095	Global analysis of protein localization in budding yeast.

Q12344	GYP5_YEAST	GTPase-activating protein GYP5	12189143	Significance of GTP hydrolysis in Ypt1p-regulated endoplasmic reticulum to Golgi transport revealed by the analysis of two novel Ypt1-GAPs.

Q3ZK22	VEZA_MOUSE	Vezatin	16199027	Vezatin, an ubiquitous adherens junction protein, is required for mouse blastocyst morphogenesis.

P23497	SP100_HUMAN	Nuclear autoantigen Sp-100	2258622	Isolation and characterization of cDNA encoding a human nuclear antigen predominantly recognized by autoantibodies from patients with primary biliary cirrhosis.

Q96FT7	ACCN4_HUMAN	Amiloride-sensitive cation channel 4	10852210	A new member of acid-sensing ion channels from pituitary gland.

P53721	AIM38_YEAST	Altered inheritance rate of mitochondria protein 38	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q9C0J9	BHE41_HUMAN	Class E basic helix-loop-helix protein 41	11162494	Molecular cloning and characterization of DEC2, a new member of basic helix-loop-helix proteins.

P01123	YPT1_YEAST	GTP-binding protein YPT1	14576435	Structure of Rab GDP-dissociation inhibitor in complex with prenylated YPT1 GTPase.

B1AY10	NFX1_MOUSE	Transcriptional repressor NF-X1	12047746	Murine NFX.1: isolation and characterization of its messenger RNA, mapping of its chromosomal location and assessment of its developmental expression.

Q8N5U6	RNF10_HUMAN	RING finger protein 10	16335786	Characterization of Mesenchyme Homeobox 2 (MEOX2) transcription factor binding to RING finger protein 10.

P38907	CHL4_YEAST	Central kinetochore subunit CHL4	12589047	Chl4p and Iml3p are two new members of the budding yeast outer kinetochore.

Q9P6N4	PEP5_SCHPO	Vacuolar membrane protein pep5	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P81917	OR43A_DROME	Odorant receptor 43a	10089887	A spatial map of olfactory receptor expression in the Drosophila antenna.

P05943	S10AA_RAT	Protein S100-A10	12050667	Annexin II light chain regulates sensory neuron-specific sodium channel expression.

Q800K6	TOB1A_XENLA	DNA topoisomerase 2-binding protein 1-A	14525986	Cut5 is required for the binding of Atr and DNA polymerase alpha to genotoxin-damaged chromatin.

P33085	SHAKB_DROME	Innexin shaking-B	9552170	The shaking B gene in Drosophila regulates the number of gap junctions between photoreceptor terminals in the lamina.

Q9C895	BRE1B_ARATH	E3 ubiquitin-protein ligase BRE1-like 2	17329563	The absence of histone H2B monoubiquitination in the Arabidopsis hub1 (rdo4) mutant reveals a role for chromatin remodeling in seed dormancy.

Q62318	TIF1B_MOUSE	Transcription intermediary factor 1-beta	11331580	The tripartite motif family identifies cell compartments.

Q9LRR7	NCED3_ARATH	9-cis-epoxycarotenoid dioxygenase NCED3, chloroplastic	15466233	Uncoupling the effects of abscisic acid on plant growth and water relations. Analysis of sto1/nced3, an abscisic acid-deficient but salt stress-tolerant mutant in Arabidopsis.

Q12494	KCS1_YEAST	Inositol hexakisphosphate kinase 1	11956213	In Saccharomyces cerevisiae, the inositol polyphosphate kinase activity of Kcs1p is required for resistance to salt stress, cell wall integrity, and vacuolar morphogenesis.

Q9SL65	ASK17_ARATH	SKP1-like protein 17	19682297	An F-box gene, CPR30, functions as a negative regulator of the defense response in Arabidopsis.

Q9FXI5	IQD32_ARATH	Protein IQ-DOMAIN 32	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q54WZ2	VACB_DICDI	Vacuolin-B	16750281	Vacuolin, a flotillin/reggie-related protein from Dictyostelium oligomerizes for endosome association.

Q9FE22	HFR1_ARATH	Transcription factor HFR1	10995393	HFR1 encodes an atypical bHLH protein that acts in phytochrome A signal transduction.

P02825	HSP71_DROME	Major heat shock 70 kDa protein Ab	6804941	Drosophila gene related to the major heat shock-induced gene is transcribed at normal temperatures and not induced by heat shock.

Q12425	ISA2_YEAST	Iron-sulfur assembly protein 2	10913600	Mitochondrial Isa2p plays a crucial role in the maturation of cellular iron-sulfur proteins.

P23787	TERA_XENLA	Transitional endoplasmic reticulum ATPase	2140770	An abundant and ubiquitous homo-oligomeric ring-shaped ATPase particle related to the putative vesicle fusion proteins Sec18p and NSF.

Q8K406	LGI3_MOUSE	Leucine-rich repeat LGI family member 3	18760330	Leucine-rich glioma inactivated 3 associates with syntaxin 1.

P16639	ATE1_YEAST	Arginyl-tRNA--protein transferase 1	2185248	Cloning and functional analysis of the arginyl-tRNA-protein transferase gene ATE1 of Saccharomyces cerevisiae.

Q8T0D4	TAN_DROME	Protein tantalus	11397012	Tantalus, a novel ASX-interacting protein with tissue-specific functions.

P47104	RAV1_YEAST	Regulator of V-ATPase in vacuolar membrane protein 1	11283612	Skp1 forms multiple protein complexes, including RAVE, a regulator of V-ATPase assembly.

P34219	TOD6_YEAST	Transcriptional regulatory protein TOD6	19158363	High-resolution DNA-binding specificity analysis of yeast transcription factors.

P60604	UB2G2_HUMAN	Ubiquitin-conjugating enzyme E2 G2	9693041	Identification, expression, and chromosomal localization of ubiquitin conjugating enzyme 7 (UBE2G2), a human homologue of the Saccharomyces cerevisiae UBC7 gene.

Q95RA8	MOB1_DROME	Mps one binder kinase activator-like 1	19913529	Mob as tumor suppressor is activated at the cell membrane to control tissue growth and organ size in Drosophila.

Q44456	MOTA_AGRT5	Motility protein A	9161425	The Agrobacterium tumefaciens motor gene, motA, is in a linked cluster with the flagellar switch protein genes, fliG, fliM and fliN.

P55965	BYN_DROME	T-related protein	7958884	Homologs of the mouse Brachyury gene are involved in the specification of posterior terminal structures in Drosophila, Tribolium, and Locusta.

Q92901	RL3L_HUMAN	60S ribosomal protein L3-like	8921388	A novel ribosomal protein L3-like gene (RPL3L) maps to the autosomal dominant polycystic kidney disease gene region.

Q10258	MTHR1_SCHPO	Methylenetetrahydrofolate reductase 1	12112238	Two non-complementing genes encoding enzymatically active methylenetetrahydrofolate reductases control methionine requirement in fission yeast Schizosaccharomyces pombe.

Q9M7Q4	AI5L5_ARATH	ABSCISIC ACID-INSENSITIVE 5-like protein 5	15361142	ABF2, an ABRE-binding bZIP factor, is an essential component of glucose signaling and its overexpression affects multiple stress tolerance.

P25932	ESCA_DROME	Protein escargot	9012491	Cadherin-mediated cell adhesion and cell motility in Drosophila trachea regulated by the transcription factor Escargot.

Q9R0K7	AT2B2_MOUSE	Plasma membrane calcium-transporting ATPase 2	9697703	Mutations in a plasma membrane Ca2+-ATPase gene cause deafness in deafwaddler mice.

Q8LGE3	ARP6_ARATH	Actin-related protein 6	16495307	EARLY IN SHORT DAYS 1 (ESD1) encodes ACTIN-RELATED PROTEIN 6 (AtARP6), a putative component of chromatin remodelling complexes that positively regulates FLC accumulation in Arabidopsis.

P15880	RS2_HUMAN	40S ribosomal protein S2	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

Q9Y5E4	PCDB5_HUMAN	Protocadherin beta-5	11322959	The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number.

Q38869	CDPK4_ARATH	Calcium-dependent protein kinase 4	17921317	Two calcium-dependent protein kinases, CPK4 and CPK11, regulate abscisic acid signal transduction in Arabidopsis.

B9DFG3	ISE2_ARATH	DEAD-box ATP-dependent RNA helicase ISE2, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q9P0L0	VAPA_HUMAN	Vesicle-associated membrane protein-associated protein A	9920726	Molecular cloning and characterization of mammalian homologues of vesicle-associated membrane protein-associated (VAMP-associated) proteins.

Q2UIM2	ABFB_ASPOR	Alpha-N-arabinofuranosidase B	16233386	Synergistic degradation of arabinoxylan with alpha-L- arabinofuranosidase, xylanase and beta-xylosidase from soy sauce koji mold, Aspergillus oryzae, in high salt condition.

P26321	RL5_YEAST	60S ribosomal protein L5	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

O43462	MBTP2_HUMAN	Membrane-bound transcription factor site-2 protease	19361614	IFAP syndrome is caused by deficiency in MBTPS2, an intramembrane zinc metalloprotease essential for cholesterol homeostasis and ER stress response.

Q9CX97	WDR55_MOUSE	WD repeat-containing protein 55	18769712	WDR55 is a nucleolar modulator of ribosomal RNA synthesis, cell cycle progression, and teleost organ development.

Q08416	IRC23_YEAST	Increased recombination centers protein 23	14562095	Global analysis of protein localization in budding yeast.

Q29983	MICA_HUMAN	MHC class I polypeptide-related sequence A	10426993	Activation of NK cells and T cells by NKG2D, a receptor for stress- inducible MICA.

Q9NZ52	GGA3_HUMAN	ADP-ribosylation factor-binding protein GGA3	10749927	A family of ADP-ribosylation factor effectors that can alter transport through the trans-Golgi.

P20333	TNR1B_HUMAN	Tumor necrosis factor receptor superfamily member 1B	8069916	A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor.

O15438	MRP3_HUMAN	Canalicular multispecific organic anion transporter 2	9738950	cDNA cloning and inducible expression of human multidrug resistance associated protein 3 (MRP3).

Q08957	AFT2_YEAST	Iron-regulated transcriptional activator AFT2	11734641	A second iron-regulatory system in yeast independent of Aft1p.

P00915	CAH1_HUMAN	Carbonic anhydrase 1	2121614	Structure and methylation patterns of the gene encoding human carbonic anhydrase I.

Q9CZQ6	RAE1E_MOUSE	Retinoic acid early-inducible protein 1-epsilon	11567106	Regulation of cutaneous malignancy by gammadelta T cells.

O22048	AOX1C_ARATH	Alternative oxidase 1c, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q04081	LCMT1_YEAST	Leucine carboxyl methyltransferase 1	11060018	Carboxyl methylation of the phosphoprotein phosphatase 2A catalytic subunit promotes its functional association with regulatory subunits in vivo.

P13099	TOP3_YEAST	DNA topoisomerase 3	15889139	RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex.

Q64127	TIF1A_MOUSE	Transcription intermediary factor 1-alpha	8978696	A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors.

Q61584	FXR1_MOUSE	Fragile X mental retardation syndrome-related protein 1	11438699	A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P.

Q7SXW4	TM111_DANRE	Transmembrane protein 111	15716502	The zebrafish pob gene encodes a novel protein required for survival of red cone photoreceptor cells.

Q09228	EGL27_CAEEL	Egg-laying defective protein 27	9927605	EGL-27 is similar to a metastasis-associated factor and controls cell polarity and cell migration in C. elegans.

Q9UTG3	YKEE_SCHPO	Uncharacterized protein C1805.14	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P25336	MSH3_YEAST	DNA mismatch repair protein MSH3	17636021	Saccharomyces cerevisiae Msh2-Msh3 acts in repair of base-base mispairs.

P18754	RCC1_HUMAN	Regulator of chromosome condensation	3678831	Isolation and characterization of the active cDNA of the human cell cycle gene (RCC1) involved in the regulation of onset of chromosome condensation.

B0FRH7	LLPH_APLKU	Protein LLP	16504946	A nucleolar protein ApLLP induces ApC/EBP expression required for long-term synaptic facilitation in aplysia neurons.

Q22830	OSM1_CAEEL	Intraflagellar transport protein osm-1	16648645	The molecular identities of the Caenorhabditis elegans intraflagellar transport genes dyf-6, daf-10 and osm-1.

Q13480	GAB1_HUMAN	GRB2-associated-binding protein 1	8596638	A Grb2-associated docking protein in EGF- and insulin-receptor signalling.

P32754	HPPD_HUMAN	4-hydroxyphenylpyruvate dioxygenase	7851880	Structure of the human 4-hydroxyphenylpyruvic acid dioxygenase gene (HPD).

Q13685	AAMP_HUMAN	Angio-associated migratory cell protein	18634987	Blockade of angio-associated migratory cell protein inhibits smooth muscle cell migration and neointima formation in accelerated atherosclerosis.

Q07973	CP24A_HUMAN	1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	8506296	Isolation and expression of human 1,25-dihydroxyvitamin D3 24- hydroxylase cDNA.

O43683	BUB1_HUMAN	Mitotic checkpoint serine/threonine-protein kinase BUB1	15525512	Phosphorylation of Cdc20 by Bub1 provides a catalytic mechanism for APC/C inhibition by the spindle checkpoint.

P33316	DUT_HUMAN	Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial	1325640	Human dUTP pyrophosphatase: cDNA sequence and potential biological importance of the enzyme.

Q54JA3	SIBE_DICDI	Integrin beta-like protein E	16699495	An adhesion molecule in free-living Dictyostelium amoebae with integrin beta features.

P32601	DSS4_YEAST	Protein DSS4	8429886	DSS4-1 is a dominant suppressor of sec4-8 that encodes a nucleotide exchange protein that aids Sec4p function.

Q9UJX5	APC4_HUMAN	Anaphase-promoting complex subunit 4	9469815	Identification of a cullin homology region in a subunit of the anaphase-promoting complex.

Q9Y4C8	RBM19_HUMAN	Probable RNA-binding protein 19	16027046	Rbm19 is a nucleolar protein expressed in crypt/progenitor cells of the intestinal epithelium.

P38838	WSS1_YEAST	DNA damage response protein WSS1	11606770	A genome-wide screen in Saccharomyces cerevisiae for genes affecting UV radiation sensitivity.

Q12959	DLG1_HUMAN	Disks large homolog 1	8922391	Two independent domains of hDlg are sufficient for subcellular targeting: the PDZ1-2 conformational unit and an alternatively spliced domain.

Q14982	OPCM_HUMAN	Opioid-binding protein/cell adhesion molecule	7721093	Cloning, sequencing and localization to chromosome 11 of a cDNA encoding a human opioid-binding cell adhesion molecule (OBCAM).

Q9NRY7	PLS2_HUMAN	Phospholipid scramblase 2	10930526	Identification of three new members of the phospholipid scramblase gene family.

Q9D6K9	LASS5_MOUSE	LAG1 longevity assurance homolog 5	15823095	Mammalian Lass6 and its related family members regulate synthesis of specific ceramides.

P78536	ADA17_HUMAN	Disintegrin and metalloproteinase domain-containing protein 17	9574564	TNF-alpha convertase enzyme from human arthritis-affected cartilage: isolation of cDNA by differential display, expression of the active enzyme, and regulation of TNF-alpha.

O13289	CATA_CANAL	Peroxisomal catalase	9573075	Cloning and sequencing of a Candida albicans catalase gene and effects of disruption of this gene.

P15153	RAC2_HUMAN	Ras-related C3 botulinum toxin substrate 2	2674130	Rac, a novel ras-related family of proteins that are botulinum toxin substrates.

P31942	HNRH3_HUMAN	Heterogeneous nuclear ribonucleoprotein H3	8999868	Cloning of human 2H9 heterogeneous nuclear ribonucleoproteins. Relation with splicing and early heat shock-induced splicing arrest.

Q95US5	BRE5_CAEEL	Beta-1,3-galactosyltransferase bre-5	10924467	Bacillus thuringiensis (Bt) toxin susceptibility and isolation of resistance mutants in the nematode Caenorhabditis elegans.

O17583	LIN10_CAEEL	Protein lin-10	10359617	Basolateral localization of the Caenorhabditis elegans epidermal growth factor receptor in epithelial cells by the PDZ protein lin- 10.

Q7Z2Z1	TICRR_HUMAN	Treslin	20080954	A vertebrate gene, ticrr, is an essential checkpoint and replication regulator.

P54851	EMP2_HUMAN	Epithelial membrane protein 2	8996089	Characterization of a tumor-associated gene, a member of a novel family of genes encoding membrane glycoproteins.

P46781	RS9_HUMAN	40S ribosomal protein S9	7772601	Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs.

P87060	POP1_SCHPO	WD repeat-containing protein pop1	9990507	Two F-box/WD-repeat proteins Pop1 and Pop2 form hetero- and homo- complexes together with cullin-1 in fission yeast SCF (Skip-cullin-1- F-box) ubiquitin ligase.

Q9UTK4	NU189_SCHPO	Nucleoporin nup189	12376568	An evolutionarily conserved fission yeast protein, Ned1, implicated in normal nuclear morphology and chromosome stability, interacts with Dis3, Pim1/RCC1 and an essential nucleoporin.

Q96252	ATP4_ARATH	ATP synthase subunit delta', mitochondrial	11743114	Proteomic approach to identify novel mitochondrial proteins in Arabidopsis.

Q99572	P2RX7_HUMAN	P2X purinoceptor 7	9038151	The permeabilizing ATP receptor, P2X7. Cloning and expression of a human cDNA.

Q9H2G9	GO45_HUMAN	Golgin-45	11056056	Genomic organization of the JEM-1 (BLZF1) gene on human chromosome 1q24: molecular cloning and analysis of its promoter region.

Q14112	NID2_HUMAN	Nidogen-2	9733643	Nidogen-2: a new basement membrane protein with diverse binding properties.

A8K7I4	CLCA1_HUMAN	Calcium-activated chloride channel regulator 1	9828122	Genomic cloning, molecular characterization, and functional analysis of human CLCA1, the first human member of the family of Ca2+-activated Cl- channel proteins.

O08562	SCN9A_RAT	Sodium channel protein type 9 subunit alpha	9037087	Identification of PN1, a predominant voltage-dependent sodium channel expressed principally in peripheral neurons.

Q06504	NAT3_YEAST	N-terminal acetyltransferase B complex catalytic subunit NAT3	12783868	Nat3p and Mdm20p are required for function of yeast NatB Nalpha- terminal acetyltransferase and of actin and tropomyosin.

P38570	ITAE_HUMAN	Integrin alpha-E	8119947	Molecular cloning of the human mucosal lymphocyte integrin alpha E subunit. Unusual structure and restricted RNA distribution.

Q08949	DDC1_YEAST	DNA damage checkpoint protein 1	11825877	A role for Ddc1 in signaling meiotic double-strand breaks at the pachytene checkpoint.

P23443	KS6B1_HUMAN	Ribosomal protein S6 kinase beta-1	17936702	S6K1-mediated disassembly of mitochondrial URI/PP1gamma complexes activates a negative feedback program that counters S6K1 survival signaling.

Q9UTN6	SNF21_SCHPO	Chromatin structure-remodeling complex subunit snf21	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q56WN1	GLN11_ARATH	Glutamine synthetase cytosolic isozyme 1-1	16472779	Arabidopsis cytosolic glutamine synthetase AtGLN1;1 is a potential substrate of AtCRK3 involved in leaf senescence.

P30876	RPB2_HUMAN	DNA-directed RNA polymerase II subunit RPB2	1518060	Primary structure of the second largest subunit of human RNA polymerase II (or B).

Q9SIB4	WOX3_ARATH	WUSCHEL-related homeobox 3	11751640	A homeobox gene, PRESSED FLOWER, regulates lateral axis-dependent development of Arabidopsis flowers.

P51800	CLCKA_HUMAN	Chloride channel protein ClC-Ka	8041726	Two highly homologous members of the ClC chloride channel family in both rat and human kidney.

P29355	SEM5_CAEEL	Sex muscle abnormal protein 5	1372395	C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 domains.

P38287	CSH1_YEAST	Mannosyl phosphorylinositol ceramide synthase CSH1	14562095	Global analysis of protein localization in budding yeast.

P36198	LHX2_RAT	LIM/homeobox protein Lhx2	7678338	LH-2: a LIM/homeodomain gene expressed in developing lymphocytes and neural cells.

Q9Y7R5	INS1_SCHPO	INSIG family protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O18373	SPS1_DROME	Selenide, water dikinase	11258485	The class 2 selenophosphate synthetase gene of Drosophila contains a functional mammalian-type SECIS.

P11230	ACHB_HUMAN	Acetylcholine receptor subunit beta	8872460	New mutations in acetylcholine receptor subunit genes reveal heterogeneity in the slow-channel congenital myasthenic syndrome.

O00481	BT3A1_HUMAN	Butyrophilin subfamily 3 member A1	9149941	A 1.1-Mb transcript map of the hereditary hemochromatosis locus.

Q9Z100	CPXM1_MOUSE	Probable carboxypeptidase X1	10073577	Identification of mouse CPX-1, a novel member of the metallocarboxypeptidase gene family with highest similarity to CPX- 2.

Q8RXX9	ATL6_ARATH	E3 ubiquitin-protein ligase ATL6	17722694	Identification of 118 Arabidopsis transcription factor and 30 ubiquitin-ligase genes responding to chitin, a plant-defense elicitor.

O75159	SOCS5_HUMAN	Suppressor of cytokine signaling 5	10773671	Cloning and expression of CIS6, chromosomal assignment to 3p22 and 2p21 by in situ hybridization.

O49484	ASK11_ARATH	SKP1-like protein 11	12169662	The F-box subunit of the SCF E3 complex is encoded by a diverse superfamily of genes in Arabidopsis.

P28178	PK2_DICDI	Protein kinase 2	18635356	PIP3-independent activation of TorC2 and PKB at the cell's leading edge mediates chemotaxis.

P21147	ACO1_YEAST	Acyl-CoA desaturase 1	1978720	The OLE1 gene of Saccharomyces cerevisiae encodes the delta 9 fatty acid desaturase and can be functionally replaced by the rat stearoyl- CoA desaturase gene.

P87245	KMS1_SCHPO	Karyogamy meiotic segregation protein 1	10899136	Telomere-led bouquet formation facilitates homologous chromosome pairing and restricts ectopic interaction in fission yeast meiosis.

O42873	PDC4_SCHPO	Putative pyruvate decarboxylase C3G9.11c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9WVM1	RGAP1_MOUSE	Rac GTPase-activating protein 1	10493933	Structure and expression of murine mgcRacGAP: its developmental regulation suggests a role for the Rac/MgcRacGAP signalling pathway in neurogenesis.

P41208	CETN2_HUMAN	Centrin-2	16760425	CP110 cooperates with two calcium-binding proteins to regulate cytokinesis and genome stability.

P51688	SPHM_HUMAN	N-sulphoglucosamine sulphohydrolase	7493035	Cloning of the sulphamidase gene and identification of mutations in Sanfilippo A syndrome.

Q9D1J1	NECP2_MOUSE	Adaptin ear-binding coat-associated protein 2	14555962	Identification of a family of endocytic proteins that define a new alpha-adaptin ear-binding motif.

Q9UTJ8	RAD50_SCHPO	DNA repair protein rad50	12944482	The fission yeast Rad32 (Mre11)-Rad50-Nbs1 complex is required for the S-phase DNA damage checkpoint.

P04911	H2A1_YEAST	Histone H2A.1	15781691	Saccharomyces cerevisiae histone H2A Ser122 facilitates DNA repair.

P20241	NRG_DROME	Neuroglian	1693086	Differential splicing generates a nervous system-specific form of Drosophila neuroglian.

Q15418	KS6A1_HUMAN	Ribosomal protein S6 kinase alpha-1	8141249	Human rsk isoforms: cloning and characterization of tissue-specific expression.

Q14C86	GAPD1_HUMAN	GTPase-activating protein and VPS9 domain-containing protein 1	16410077	Rab5-activating protein 6, a novel endosomal protein with a role in endocytosis.

P40358	JEM1_YEAST	DnaJ-like chaperone JEM1	12493774	Nep98p is a component of the yeast spindle pole body and essential for nuclear division and fusion.

Q8L840	RQL4A_ARATH	ATP-dependent DNA helicase Q-like 4A	16146519	Arabidopsis RecQI4A suppresses homologous recombination and modulates DNA damage responses.

Q9FH18	WIP2_ARATH	WPP domain-interacting protein 2	18591351	Two distinct interacting classes of nuclear envelope-associated coiled-coil proteins are required for the tissue-specific nuclear envelope targeting of Arabidopsis RanGAP.

Q6LFN2	ZNRF1_PLAF7	RING finger protein PFF0165c	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

A7UDM9	IXOSB_IXOSI	Ixosin-B	18295522	Purification and cloning of a novel antimicrobial peptide from salivary glands of the hard tick, Ixodes sinensis.

P0A6T5	GCH1_ECOLI	GTP cyclohydrolase 1	12559918	Biosynthesis of pteridines. Reaction mechanism of GTP cyclohydrolase I.

P49740	NDK_SCHPO	Nucleoside diphosphate kinase	7499258	Cloning and functional analysis of the ndk1 gene encoding nucleoside- diphosphate kinase in Schizosaccharomyces pombe.

Q8WUA7	TB22A_HUMAN	TBC1 domain family member 22A	18186464	First crystallographic models of human TBC domains in the context of a family-wide structural analysis.

O64629	AUR3_ARATH	Serine/threonine-protein kinase Aurora-3	16028112	Characterization of plant Aurora kinases during mitosis.

Q8BRM2	GORAB_MOUSE	RAB6-interacting golgin	12783284	Cloning and characterization of a novel gene which encodes a protein interacting with the mitosis-associated kinase-like protein NTKL.

Q8UW72	HE71B_XENLA	Transcription factor HES-7.1-B	15935340	Identification of target genes for the Xenopus Hes-related protein XHR1, a prepattern factor specifying the midbrain-hindbrain boundary.

O35806	LTBP2_RAT	Latent-transforming growth factor beta-binding protein 2	10028916	TGF-beta1-dependent differential expression of a rat homolog for latent TGF-beta binding protein in astrocytes and C6 glioma cells.

P43299	PROL_ARATH	Protein PROLIFERA	10751170	The essential Mcm7 protein PROLIFERA is localized to the nucleus of dividing cells during the G(1) phase and is required maternally for early Arabidopsis development.

P47158	CAF17_YEAST	Putative transferase CAF17, mitochondrial	18086897	Mitochondrial Iba57p is required for Fe/S cluster formation on aconitase and activation of radical SAM enzymes.

P46095	GPR6_HUMAN	G-protein coupled receptor 6	7832990	Isolation of three novel human genes encoding G protein-coupled receptors.

Q38871	CDPK5_ARATH	Calcium-dependent protein kinase 5	12068094	Calcium signaling through protein kinases. The Arabidopsis calcium- dependent protein kinase gene family.

Q12466	TCB1_YEAST	Tricalbin-1	15049706	The tricalbin C2 domains: lipid-binding properties of a novel, synaptotagmin-like yeast protein family.

Q9WU22	PTN4_MOUSE	Tyrosine-protein phosphatase non-receptor type 4	11054567	Molecular cloning and characterization of a protein tyrosine phosphatase enriched in testis, a putative murine homologue of human PTPMEG.

Q96Q42	ALS2_HUMAN	Alsin	11586298	A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2.

Q9FNJ8	AROD5_ARATH	Arogenate dehydratase 5, chloroplastic	17726025	Phenylalanine biosynthesis in Arabidopsis thaliana. Identification and characterization of arogenate dehydratases.

Q02354	UTP6_YEAST	U3 small nucleolar RNA-associated protein 6	12150911	90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors.

O13807	DDB1_SCHPO	DNA damage-binding protein 1	12181326	Characterization of a Schizosaccharomyces pombe strain deleted for a sequence homologue of the human damaged DNA binding 1 (DDB1) gene.

P08575	PTPRC_HUMAN	Receptor-type tyrosine-protein phosphatase C	2845400	The leukocyte common antigen (CD45): a putative receptor-linked protein tyrosine phosphatase.

P19957	ELAF_HUMAN	Elafin	8476637	Characterization and gene sequence of the precursor of elafin, an elastase-specific inhibitor in bronchial secretions.

P75780	FIU_ECOLI	Catecholate siderophore receptor fiu	10806384	Proteomic analysis of the Escherichia coli outer membrane.

P63096	GNAI1_HUMAN	Guanine nucleotide-binding protein G(i) subunit alpha-1	2834384	Presence of three distinct molecular species of Gi protein alpha subunit. Structure of rat cDNAs and human genomic DNAs.

P51151	RAB9A_HUMAN	Ras-related protein Rab-9A	15263003	High resolution crystal structure of human Rab9 GTPase: a novel antiviral drug target.

Q9BQA1	MEP50_HUMAN	Methylosome protein 50	12972618	Purification and identification of a novel complex which is involved in androgen receptor-dependent transcription.

P46676	SUM1_YEAST	Suppressor of mar1-1 protein	12612074	Rfm1, a novel tethering factor required to recruit the hst1 histone deacetylase for repression of middle sporulation genes.

Q9ZU91	E133_ARATH	Glucan endo-1,3-beta-glucosidase 3	12805588	Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis.

Q8CHN8	MASP1_RAT	Mannan-binding lectin serine protease 1	12847554	Murine serine proteases MASP-1 and MASP-3, components of the lectin pathway activation complex of complement, are encoded by a single structural gene.

Q12406	ARP7_YEAST	Actin-related protein 7	16204215	The RSC chromatin remodeling complex bears an essential fungal- specific protein module with broad functional roles.

P38789	SSF1_YEAST	Ribosome biogenesis protein SSF1	7748491	An essential gene pair in Saccharomyces cerevisiae with a potential role in mating.

Q9C0X0	YB8L_SCHPO	Uncharacterized protein C29A3.21	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P43292	SRK2G_ARATH	Serine/threonine-protein kinase SRK2G	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

Q9V4M2	WECH_DROME	Protein wech	18327251	The NHL-domain protein Wech is crucial for the integrin-cytoskeleton link.

P29466	CASP1_HUMAN	Caspase-1	15030775	NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder.

O13601	RSP1_SCHPO	DnaJ-related protein rsp1	15068790	Rsp1p, a J domain protein required for disassembly and assembly of microtubule organizing centers during the fission yeast cell cycle.

P49407	ARRB1_HUMAN	Beta-arrestin-1	16378096	Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling.

O55135	IF6_MOUSE	Eukaryotic translation initiation factor 6	9374518	Isolation of a novel beta4 integrin-binding protein (p27(BBP)) highly expressed in epithelial cells.

P59780	AP3S2_HUMAN	AP-3 complex subunit sigma-2	9118953	AP-3: an adaptor-like protein complex with ubiquitous expression.

Q01112	CDC42_SCHPO	Cell division control protein 42 homolog	8289788	Cdc42p GTPase is involved in controlling polarized cell growth in Schizosaccharomyces pombe.

P97489	GATA5_MOUSE	Transcription factor GATA-5	9119112	GATA-5: a transcriptional activator expressed in a novel temporally and spatially-restricted pattern during embryonic development.

Q8CC35	SYNPO_MOUSE	Synaptopodin	9314539	Synaptopodin: an actin-associated protein in telencephalic dendrites and renal podocytes.

O80982	HSFA2_ARATH	Heat stress transcription factor A-2	17059409	Arabidopsis heat shock transcription factor A2 as a key regulator in response to several types of environmental stress.

Q949S9	SPF27_ARATH	Pre-mRNA-splicing factor SPF27 homolog	17575050	Regulation of plant innate immunity by three proteins in a complex conserved across the plant and animal kingdoms.

P01877	IGHA2_HUMAN	Ig alpha-2 chain C region	6421489	Mechanisms of divergence and convergence of the human immunoglobulin alpha 1 and alpha 2 constant region gene sequences.

O75610	LFTY1_HUMAN	Left-right determination factor 1	10053005	Characterization and mutation analysis of human LEFTY A and LEFTY B, homologues of murine genes implicated in left-right axis development.

Q96B97	SH3K1_HUMAN	SH3 domain-containing kinase-binding protein 1	15962011	Sprouty2 acts at the Cbl/CIN85 interface to inhibit epidermal growth factor receptor downregulation.

Q8BPP1	MB212_MOUSE	Protein mab-21-like 2	10556287	Two murine and human homologs of mab-21, a cell fate determination gene involved in Caenorhabditis elegans neural development.

Q9C550	LEU12_ARATH	2-isopropylmalate synthase 2, chloroplastic	17189332	Two Arabidopsis genes (IPMS1 and IPMS2) encode isopropylmalate synthase, the branchpoint step in the biosynthesis of leucine.

O88846	RNF4_RAT	E3 ubiquitin ligase RNF4	11319220	The RING finger protein SNURF is a bifunctional protein possessing DNA binding activity.

P07213	TOM70_YEAST	Mitochondrial import receptor subunit TOM70	11502169	Yeast mitochondrial dehydrogenases are associated in a supramolecular complex.

Q62758	5HT4R_RAT	5-hydroxytryptamine receptor 4	10220570	Novel brain-specific 5-HT4 receptor splice variants show marked constitutive activity: role of the C-terminal intracellular domain.

P84053	H2A_DROHY	Histone H2A	2109309	Isolation and characterization of a Drosophila hydei histone DNA repeat unit.

Q24535	SRF_DROME	Serum response factor homolog	8787734	The Drosophila serum response factor gene is required for the formation of intervein tissue of the wing and is allelic to blistered.

Q6NPM8	IMPL2_ARATH	Phosphatase IMPL2, chloroplastic	19339506	VTC4 is a bifunctional enzyme that affects myoinositol and ascorbate biosynthesis in plants.

Q96T60	PNKP_HUMAN	Bifunctional polynucleotide phosphatase/kinase	10446192	Molecular cloning of the human gene, PNKP, encoding a polynucleotide kinase 3'-phosphatase and evidence for its role in repair of DNA strand breaks caused by oxidative damage.

Q07830	GPI13_YEAST	GPI ethanolamine phosphate transferase 3	10793139	Glycosylphosphatidylinositol biosynthesis defects in Gpi11p- and Gpi13p-deficient yeast suggest a branched pathway and implicate gpi13p in phosphoethanolamine transfer to the third mannose.

P47196	AKT1_RAT	RAC-alpha serine/threonine-protein kinase	9632753	Requirement for activation of the serine-threonine kinase Akt (protein kinase B) in insulin stimulation of protein synthesis but not of glucose transport.

P30793	GCH1_HUMAN	GTP cyclohydrolase 1	7730309	Characterization of mouse and human GTP cyclohydrolase I genes. Mutations in patients with GTP cyclohydrolase I deficiency.

P48448	AL3B2_HUMAN	Aldehyde dehydrogenase family 3 member B2	8890755	Sequencing and expression of the human ALDH8 encoding a new member of the aldehyde dehydrogenase family.

O60909	B4GT2_HUMAN	Beta-1,4-galactosyltransferase 2	9405390	A family of human beta4-galactosyltransferases. Cloning and expression of two novel UDP-galactose:beta-n-acetylglucosamine beta1, 4-galactosyltransferases, beta4Gal-T2 and beta4Gal-T3.

P38419	LOXC1_ORYSJ	Lipoxygenase 7, chloroplastic	7508918	A novel lipoxygenase from rice. Primary structure and specific expression upon incompatible infection with rice blast fungus.

P0ACF0	DBHA_ECOLI	DNA-binding protein HU-alpha	227733	Native Escherichia coli HU protein is a heterotypic dimer.

P52950	DBX1_MOUSE	Homeobox protein DBX1	11239429	Control of interneuron fate in the developing spinal cord by the progenitor homeodomain protein Dbx1.

P08905	LYZ2_MOUSE	Lysozyme C-2	12411294	Increased inflammation in lysozyme M-deficient mice in response to Micrococcus luteus and its peptidoglycan.

Q53EU6	GPAT3_HUMAN	Glycerol-3-phosphate acyltransferase 3	17002884	Identification of a novel human lysophosphatidic acid acyltransferase, LPAAT-theta, which activates mTOR pathway.

P32469	DPH5_YEAST	Diphthine synthase	14562095	Global analysis of protein localization in budding yeast.

Q9Y738	MIS12_SCHPO	Centromere protein mis12	10398680	Proper metaphase spindle length is determined by centromere proteins Mis12 and Mis6 required for faithful chromosome segregation.

Q04601	APC4_YEAST	Anaphase-promoting complex subunit 4	9469814	Mass spectrometric analysis of the anaphase-promoting complex from yeast: identification of a subunit related to cullins.

P32597	STH1_YEAST	Nuclear protein STH1/NPS1	16204215	The RSC chromatin remodeling complex bears an essential fungal- specific protein module with broad functional roles.

Q24572	CAF1_DROME	Probable histone-binding protein Caf1	12408864	Histone methyltransferase activity of a Drosophila Polycomb group repressor complex.

Q16799	RTN1_HUMAN	Reticulon-1	8833145	Genomic organization of the human NSP gene, prototype of a novel gene family encoding reticulons.

P32131	HEMN_ECOLI	Oxygen-independent coproporphyrinogen-III oxidase	12114526	Oxygen-independent coproporphyrinogen-III oxidase HemN from Escherichia coli.

Q10156	LKH1_SCHPO	Dual specificity protein kinase lkh1	12565823	The kic1 kinase of schizosaccharomyces pombe is a CLK/STY orthologue that regulates cell-cell separation.

Q9CSN1	SNW1_MOUSE	SNW domain-containing protein 1	17592128	Evolution of Na,K-ATPase betam-subunit into a coregulator of transcription in placental mammals.

Q9JK83	PAR6B_MOUSE	Partitioning defective 6 homolog beta	10934474	The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42.

O74465	HRR1_SCHPO	Helicase required for RNAi-mediated heterochromatin assembly 1	15607976	Two RNAi complexes, RITS and RDRC, physically interact and localize to noncoding centromeric RNAs.

Q62520	ZIC2_MOUSE	Zinc finger protein ZIC 2	11756505	Zic2 controls cerebellar development in cooperation with Zic1.

Q0H293	BDEF_AEQIR	Big defensin	16597463	Molecular cloning, expression of a big defensin gene from bay scallop Argopecten irradians and the antimicrobial activity of its recombinant protein.

Q12483	SNF8_YEAST	Vacuolar-sorting protein SNF8	7785322	Molecular analysis of the SNF8 gene of Saccharomyces cerevisiae.

P42677	RS27_HUMAN	40S ribosomal protein S27	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

Q94AI7	TPL_ARATH	Protein TOPLESS	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

Q15544	TAF11_HUMAN	Transcription initiation factor TFIID subunit 11	9695952	Human TAF(II)28 and TAF(II)18 interact through a histone fold encoded by atypical evolutionary conserved motifs also found in the SPT3 family.

O14905	WNT9B_HUMAN	Protein Wnt-9b	9441749	Isolation of two novel WNT genes, WNT14 and WNT15, one of which (WNT15) is closely linked to WNT3 on human chromosome 17q21.

P37297	STT4_YEAST	Phosphatidylinositol 4-kinase STT4	8288577	A novel gene, STT4, encodes a phosphatidylinositol 4-kinase in the PKC1 protein kinase pathway of Saccharomyces cerevisiae.

P07276	RAD2_YEAST	DNA repair protein RAD2	8247134	Yeast excision repair gene RAD2 encodes a single-stranded DNA endonuclease.

Q02959	HOS3_YEAST	Histone deacetylase HOS3	10535926	Yeast HOS3 forms a novel trichostatin A-insensitive homodimer with intrinsic histone deacetylase activity.

P41279	M3K8_HUMAN	Mitogen-activated protein kinase kinase kinase 8	2072910	Structure and transforming potential of the human cot oncogene encoding a putative protein kinase.

Q99816	TS101_HUMAN	Tumor susceptibility gene 101 protein	19520058	Penta-EF-hand protein ALG-2 functions as a Ca2+-dependent adaptor that bridges Alix and TSG101.

O00203	AP3B1_HUMAN	AP-3 complex subunit beta-1	9151686	Characterization of the adaptor-related protein complex, AP-3.

Q84J50	HS177_ORYSJ	17.7 kDa class I heat shock protein	15803416	Characterization of the genomic structures and selective expression profiles of nine class I small heat shock protein genes clustered on two chromosomes in rice (Oryza sativa L.).

Q9Z1P8	ANGL4_MOUSE	Angiopoietin-related protein 4	10866690	Peroxisome proliferator-activated receptor gamma target gene encoding a novel angiopoietin-related protein associated with adipose differentiation.

P56371	RAB4A_MOUSE	Ras-related protein Rab-4A	11172003	A FYVE-finger-containing protein, Rabip4, is a Rab4 effector involved in early endosomal traffic.

Q9FQ09	KU80_ARATH	ATP-dependent DNA helicase 2 subunit KU80	12148535	Identification of Ku70 and Ku80 homologues in Arabidopsis thaliana: evidence for a role in the repair of DNA double-strand breaks.

O14064	BIR1_SCHPO	Protein bir1	11861551	Schizosaccharomyces pombe Bir1p, a nuclear protein that localizes to kinetochores and the spindle midzone, is essential for chromosome condensation and spindle elongation during mitosis.

Q9P6K0	YLA3_SCHPO	Uncharacterized HTH La-type RNA-binding protein C1527.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P70352	NAR5_MOUSE	Ecto-ADP-ribosyltransferase 5	11587854	Structure, chromosomal localization, and expression of the gene for mouse ecto-mono(ADP-ribosyl)transferase ART5.

Q9EPL8	IPO7_MOUSE	Importin-7	11493596	Multiple pathways contribute to nuclear import of core histones.

P39707	SEN34_YEAST	tRNA-splicing endonuclease subunit SEN34	9200603	The yeast tRNA splicing endonuclease: a tetrameric enzyme with two active site subunits homologous to the archaeal tRNA endonucleases.

P22812	TUBE_DROME	Protein Tube	7635064	Interaction of the pelle kinase with the membrane-associated protein tube is required for transduction of the dorsoventral signal in Drosophila embryos.

O00505	IMA3_HUMAN	Importin subunit alpha-3	9435235	Cloning and characterization of hSRP1 gamma, a tissue-specific nuclear transport factor.

O00584	RNT2_HUMAN	Ribonuclease T2	9192857	Mammalian Rh/T2/S-glycoprotein ribonuclease family genes: cloning of a human member located in a region of chromosome 6 (6q27) frequently deleted in human malignancies.

P62701	RS4X_HUMAN	40S ribosomal protein S4, X isoform	1795030	Molecular cloning of the human gene, CCG2, that complements the BHK- derived temperature-sensitive cell cycle mutant tsBN63: identity of CCG2 with the human X chromosomal SCAR/RPS4X gene.

O74427	URK1_SCHPO	Uridine kinase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P52591	PO121_RAT	Nuclear envelope pore membrane protein POM 121	8335683	An integral membrane protein of the pore membrane domain of the nuclear envelope contains a nucleoporin-like region.

Q86VP6	CAND1_HUMAN	Cullin-associated NEDD8-dissociated protein 1	12504025	NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases.

O43889	CREB3_HUMAN	Cyclic AMP-responsive element-binding protein 3	9271389	Luman, a new member of the CREB/ATF family, binds to herpes simplex virus VP16-associated host cellular factor.

O60779	S19A2_HUMAN	Thiamine transporter 1	10542220	Cloning of the human thiamine transporter, a member of the folate transporter family.

Q9BLG0	TNNC_TODPA	Troponin C	11435133	Amino acid sequence of squid troponin C.

P97466	NOGG_MOUSE	Noggin	9585504	Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite.

P17612	KAPCA_HUMAN	cAMP-dependent protein kinase catalytic subunit alpha	2843813	A cDNA clone encoding human cAMP-dependent protein kinase catalytic subunit C alpha.

Q08923	CTI6_YEAST	Histone deacetylase complex subunit CTI6	12086626	Cti6, a PHD domain protein, bridges the Cyc8-Tup1 corepressor and the SAGA coactivator to overcome repression at GAL1.

Q24472	RBF_DROME	Retinoblastoma family protein	15545624	Identification of a Drosophila Myb-E2F2/RBF transcriptional repressor complex.

P97836	DLGP1_RAT	Disks large-associated protein 1	9115257	SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density.

Q13285	STF1_HUMAN	Steroidogenic factor 1	10369247	A mutation in the gene encoding steroidogenic factor-1 causes XY sex reversal and adrenal failure in humans.

O35144	TERF2_MOUSE	Telomeric repeat-binding factor 2	9326950	Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2.

O14032	YEMB_SCHPO	UPF0664 stress-induced protein C29B12.11c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q5EGZ1	ACE2_RAT	Angiotensin-converting enzyme 2	15671045	Myocardial infarction increases ACE2 expression in rat and humans.

Q96J02	ITCH_HUMAN	E3 ubiquitin-protein ligase Itchy homolog	19116316	The E3 ubiquitin ligase atrophin interacting protein 4 binds directly to the chemokine receptor CXCR4 via a novel WW domain-mediated interaction.

Q8K2J0	PLCD3_MOUSE	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3	16314520	Phospholipase C-delta1 and -delta3 are essential in the trophoblast for placental development.

Q04629	SWF1_YEAST	Palmitoyltransferase SWF1	15973437	Swf1-dependent palmitoylation of the SNARE Tlg1 prevents its ubiquitination and degradation.

Q9NWQ8	PAG1_HUMAN	Phosphoprotein associated with glycosphingolipid-enriched microdomains 1	10790433	Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation.

Q08960	TYW1_YEAST	tRNA wybutosine-synthesizing protein 1	14562095	Global analysis of protein localization in budding yeast.

Q13868	EXOS2_HUMAN	Exosome complex exonuclease RRP4	8600032	The 3' end of yeast 5.8S rRNA is generated by an exonuclease processing mechanism.

P50052	AGTR2_HUMAN	Type-2 angiotensin II receptor	7945336	Human type 2 angiotensin II receptor gene: cloned, mapped to the X chromosome, and its mRNA is expressed in the human lung.

Q9Z248	AEBP2_MOUSE	Zinc finger protein AEBP2	10329662	Cloning and characterization of a novel zinc finger transcriptional repressor. A direct role of the zinc finger motif in repression.

Q04299	YMX7_YEAST	Probable ADP-ribose 1''-phosphate phosphatase YML087W	15722447	Structure and mechanism of ADP-ribose-1''-monophosphatase (Appr-1''- pase), a ubiquitous cellular processing enzyme.

Q19791	GON1_CAEEL	A disintegrin and metalloproteinase with thrombospondin motifs gon-1	10376599	Control of organ shape by a secreted metalloprotease in the nematode Caenorhabditis elegans.

P52286	SKP1_YEAST	Suppressor of kinetochore protein 1	8706132	Budding yeast SKP1 encodes an evolutionarily conserved kinetochore protein required for cell cycle progression.

Q8N2W9	PIAS4_HUMAN	E3 SUMO-protein ligase PIAS4	11248056	A transcriptional corepressor of Stat1 with an essential LXXLL signature motif.

Q02804	ARL3_YEAST	ADP-ribosylation factor-like protein 3	15077113	Targeting of the Arf-like GTPase Arl3p to the Golgi requires N- terminal acetylation and the membrane protein Sys1p.

Q9SR37	BGL23_ARATH	Beta-glucosidase 23	12581307	A novel ER-derived compartment, the ER body, selectively accumulates a beta-glucosidase with an ER-retention signal in Arabidopsis.

Q02763	TIE2_HUMAN	Angiopoietin-1 receptor	8980225	Vascular dysmorphogenesis caused by an activating mutation in the receptor tyrosine kinase TIE2.

O43529	CHSTA_HUMAN	Carbohydrate sulfotransferase 10	9478973	Expression cloning of a human sulfotransferase that directs the synthesis of the HNK-1 glycan on the neural cell adhesion molecule and glycolipids.

P00944	XYLA_ECOLI	Xylose isomerase	2405386	Identification of essential histidine residues in the active site of Escherichia coli xylose (glucose) isomerase.

O75578	ITA10_HUMAN	Integrin alpha-10	9685391	Isolation, cloning, and sequence analysis of the integrin subunit alpha10, a beta1-associated collagen binding integrin expressed on chondrocytes.

P24242	ASCG_ECOLI	HTH-type transcriptional regulator AscG	1630307	Nucleotide sequence, function, activation, and evolution of the cryptic asc operon of Escherichia coli K12.

Q0GA42	CNNM1_MOUSE	Metal transporter CNNM1	14723793	Molecular cloning and characterization of the mouse Acdp gene family.

P46993	ASG7_YEAST	Protein ASG7	11073983	Localization and signaling of G(beta) subunit Ste4p are controlled by a-factor receptor and the a-specific protein Asg7p.

P12645	BMP3_HUMAN	Bone morphogenetic protein 3	3201241	Novel regulators of bone formation: molecular clones and activities.

Q8VHR0	PCD18_MOUSE	Protocadherin 18	11716507	Disabled-1 interacts with a novel developmentally regulated protocadherin.

Q9C9D0	SOT16_ARATH	Sulfotransferase 16	15358770	Desulfoglucosinolate sulfotransferases from Arabidopsis thaliana catalyze the final step in the biosynthesis of the glucosinolate core structure.

Q8CFA1	IRAK2_MOUSE	Interleukin-1 receptor-associated kinase-like 2	15082713	The murine IRAK2 gene encodes four alternatively spliced isoforms, two of which are inhibitory.

P16221	COX8B_RAT	Cytochrome c oxidase subunit 8B, mitochondrial	8939982	The role of an E box binding basic helix loop helix protein in the cardiac muscle-specific expression of the rat cytochrome oxidase subunit VIII gene.

Q12071	VPS54_YEAST	Vacuolar protein sorting-associated protein 54	12686613	Vps51p mediates the association of the GARP (Vps52/53/54) complex with the late Golgi t-SNARE Tlg1p.

P26639	SYTC_HUMAN	Threonyl-tRNA synthetase, cytoplasmic	2033077	Nucleotide and deduced amino acid sequence of human threonyl-tRNA synthetase reveals extensive homology to the Escherichia coli and yeast enzymes.

P40231	CSK2A_SCHPO	Casein kinase II subunit alpha	8187760	Genetic analysis of cell morphogenesis in fission yeast -- a role for casein kinase II in the establishment of polarized growth.

Q6PDU5	BEX3_RAT	Protein BEX3	15958283	Characterization of the Bex gene family in humans, mice, and rats.

P36051	MCD4_YEAST	GPI ethanolamine phosphate transferase 1	10514566	A novel vacuolar protein encoded by SSU21 / MCD4 is involved in cell wall integrity in yeast.

P97445	CAC1A_MOUSE	Voltage-dependent P/Q-type calcium channel subunit alpha-1A	8929530	Absence epilepsy in tottering mutant mice is associated with calcium channel defects.

P93015	SPL3_ARATH	Squamosa promoter-binding-like protein 3	16914499	Temporal regulation of shoot development in Arabidopsis thaliana by miR156 and its target SPL3.

P10080	SSBP1_YEAST	Single-stranded nucleic acid-binding protein	2121740	SSB-1 of the yeast Saccharomyces cerevisiae is a nucleolar-specific, silver-binding protein that is associated with the snR10 and snR11 small nuclear RNAs.

A1Z9R4	ZN423_DROME	Zinc finger protein 423 homolog	17323106	DmOAZ, the unique Drosophila melanogaster OAZ homologue is involved in posterior spiracle development.

Q08495	DEMA_HUMAN	Dematin	7615546	Isoform cloning, actin binding, and chromosomal localization of human erythroid dematin, a member of the villin superfamily.

Q7KU24	CHD1_DROME	Chromodomain-helicase-DNA-binding protein 1	8692958	CHD1 is concentrated in interbands and puffed regions of Drosophila polytene chromosomes.

O60478	G137B_HUMAN	Integral membrane protein GPR137B	9521871	Cloning and characterization of a novel gene (TM7SF1) encoding a putative seven-pass transmembrane protein that is upregulated during kidney development.

Q5EAK6	ATM_DROME	Serine/threonine-protein kinase ATM	15296750	ATM is required for telomere maintenance and chromosome stability during Drosophila development.

Q8R5M8	CADM1_MOUSE	Cell adhesion molecule 1	12202822	SynCAM, a synaptic adhesion molecule that drives synapse assembly.

Q9PSN0	LECG_BITAR	Galactose-specific lectin	8593494	Primary structure of the lectin from the venom of Bitis arietans (puff-adder).

Q93VD3	CIPKN_ARATH	CBL-interacting serine/threonine-protein kinase 23	16814720	A protein kinase, interacting with two calcineurin B-like proteins, regulates K+ transporter AKT1 in Arabidopsis.

P20062	TCO2_HUMAN	Transcobalamin-2	3782074	Purification and molecular characterization of human transcobalamin II.

P53953	SFB2_YEAST	SED5-binding protein 2	10749860	Sfb2p, a yeast protein related to Sec24p, can function as a constituent of COPII coats required for vesicle budding from the endoplasmic reticulum.

P45379	TNNT2_HUMAN	Troponin T, cardiac muscle	8205619	Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere.

P38691	KSP1_YEAST	Serine/threonine-protein kinase KSP1	8676864	Allele-specific suppression of a Saccharomyces cerevisiae prp20 mutation by overexpression of a nuclear serine/threonine protein kinase.

Q8BG67	EFR3A_MOUSE	Protein EFR3 homolog A	15363888	Mouse homolog of KIAA0143 protein: hearing deficit induces specific changes of expression in auditory brainstem neurons.

P84029	CYC2_DROME	Cytochrome c-2	2987802	Characterization of two Drosophila melanogaster cytochrome c genes and their transcripts.

P35858	ALS_HUMAN	Insulin-like growth factor-binding protein complex acid labile subunit	1379671	Structure and functional expression of the acid-labile subunit of the insulin-like growth factor-binding protein complex.

O43290	SNUT1_HUMAN	U4/U6.U5 tri-snRNP-associated protein 1	9449708	A gene encoding antigenic peptides of human squamous cell carcinoma recognized cytotoxic T lymphocytes.

Q5TIS6	NOTO_MOUSE	Homeobox protein notochord	15231714	The mouse homeobox gene Not is required for caudal notochord development and affected by the truncate mutation.

P67809	YBOX1_HUMAN	Nuclease-sensitive element-binding protein 1	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

P40465	CSM2_YEAST	Chromosome segregation in meiosis protein 2	15654096	A genetic screen for top3 suppressors in Saccharomyces cerevisiae identifies SHU1, SHU2, PSY3 and CSM2: four genes involved in error- free DNA repair.

Q53EU6	GPAT3_HUMAN	Glycerol-3-phosphate acyltransferase 3	17170135	Molecular identification of microsomal acyl-CoA:glycerol-3-phosphate acyltransferase, a key enzyme in de novo triacylglycerol synthesis.

O00560	SDCB1_HUMAN	Syntenin-1	11179419	Characterization of syntenin, a syndecan-binding PDZ protein, as a component of cell adhesion sites and microfilaments.

Q38874	STM_ARATH	Homeobox protein SHOOT MERISTEMLESS	11701881	The Arabidopsis BELL1 and KNOX TALE homeodomain proteins interact through a domain conserved between plants and animals.

Q9GZL7	WDR12_HUMAN	Ribosome biogenesis protein WDR12	17353269	Interdependence of Pes1, Bop1, and WDR12 controls nucleolar localization and assembly of the PeBoW complex required for maturation of the 60S ribosomal subunit.

Q9PUK8	FZD7A_XENLA	Frizzled-7-A	11477687	Xenopus frizzled-7 morphant displays defects in dorsoventral patterning and convergent extension movements during gastrulation.

Q08647	PUS7_YEAST	Multisubstrate pseudouridine synthase 7	18332121	Different mechanisms for pseudouridine formation in yeast 5S and 5.8S rRNAs.

P35817	BDF1_YEAST	Bromodomain-containing factor 1	10783167	Bromodomain factor 1 corresponds to a missing piece of yeast TFIID.

Q9NVW2	RNF12_HUMAN	E3 ubiquitin-protein ligase RLIM	11013082	Functional characterization of the gene encoding RLIM, the corepressor of LIM homeodomain transcription factors.

Q9NYA1	SPHK1_HUMAN	Sphingosine kinase 1	12080051	Cloning and characterization of a protein kinase A anchoring protein (AKAP)-related protein that interacts with and regulates sphingosine kinase 1 activity.

Q12981	SEC20_HUMAN	Vesicle transport protein SEC20	7954800	Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins.

P26785	RL16B_YEAST	60S ribosomal protein L16-B	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q04116	YHP1_YEAST	Homeobox protein YHP1	12464632	Complex transcriptional circuitry at the G1/S transition in Saccharomyces cerevisiae.

P09529	INHBB_HUMAN	Inhibin beta B chain	3754442	Structure of two human ovarian inhibins.

Q7TN37	TRPM4_MOUSE	Transient receptor potential cation channel subfamily M member 4	12893253	Identification and characterization of the murine TRPM4 channel.

P11881	ITPR1_MOUSE	Inositol 1,4,5-trisphosphate receptor type 1	15652484	Subtype-specific and ER lumenal environment-dependent regulation of inositol 1,4,5-trisphosphate receptor type 1 by ERp44.

P42568	AF9_HUMAN	Protein AF-9	8506309	Genes on chromosomes 4, 9, and 19 involved in 11q23 abnormalities in acute leukemia share sequence homology and/or common motifs.

O13952	CNL2_SCHPO	Centromere-localized protein 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P0A9P6	DEAD_ECOLI	Cold-shock DEAD box protein A	15196029	Studies on three E. coli DEAD-box helicases point to an unwinding mechanism different from that of model DNA helicases.

P07307	ASGR2_HUMAN	Asialoglycoprotein receptor 2	3863106	Sequence of a second human asialoglycoprotein receptor: conservation of two receptor genes during evolution.

Q6NPD7	NUD10_ARATH	Nudix hydrolase 10	15878881	Comprehensive analysis of cytosolic nudix hydrolases in Arabidopsis thaliana.

Q15024	EXOS7_HUMAN	Exosome complex exonuclease RRP42	11719186	AU binding proteins recruit the exosome to degrade ARE-containing mRNAs.

Q62918	NELL2_RAT	Protein kinase C-binding protein NELL2	10548494	Biochemical characterization and expression analysis of neural thrombospondin-1-like proteins NELL1 and NELL2.

Q9Y738	MIS12_SCHPO	Centromere protein mis12	12773390	The role of Ppe1/PP6 phosphatase for equal chromosome segregation in fission yeast kinetochore.

P85004	AMML_ASTMO	Antifungal lectin AMML	16140255	A novel homodimeric lectin from Astragalus mongholicus with antifungal activity.

P08263	GSTA1_HUMAN	Glutathione S-transferase A1	1731620	Isolation and characterization of a human glutathione S-transferase Ha1 subunit gene.

A7MCT6	EKI2_MOUSE	Ethanolamine kinase 2	16861741	Placental thrombosis and spontaneous fetal death in mice deficient in ethanolamine kinase 2.

P84843	VASOT_HYBBI	Vasotab	16391356	Vasotab, a vasoactive peptide from horse fly Hybomitra bimaculata (Diptera, Tabanidae) salivary glands.

Q04344	HNT1_YEAST	Hit family protein 1	11805111	Adenosine monophosphoramidase activity of Hint and Hnt1 supports function of Kin28, Ccl1, and Tfb3.

O54715	VAS1_RAT	V-type proton ATPase subunit S1	10686355	Age-dependent increase in C7-1 gene expression in rat frontal cortex.

Q96T88	UHRF1_HUMAN	E3 ubiquitin-protein ligase UHRF1	10646863	ICBP90, a novel human CCAAT binding protein, involved in the regulation of topoisomerase IIa expression.

P0AC41	DHSA_ECOLI	Succinate dehydrogenase flavoprotein subunit	16079137	Protein complexes of the Escherichia coli cell envelope.

Q9UBD6	RHCG_HUMAN	Ammonium transporter Rh type C	12204676	RhCG is downregulated in oesophageal squamous cell carcinomas, but expressed in multiple squamous epithelia.

Q80T11	USH1G_MOUSE	Usher syndrome type-1G protein homolog	12588793	Mutations in a new scaffold protein Sans cause deafness in Jackson shaker mice.

O95633	FSTL3_HUMAN	Follistatin-related protein 3	16336961	A novel role for fibronectin type I domain in the regulation of human hematopoietic cell adhesiveness through binding to follistatin domains of FLRG and follistatin.

Q868T3	CCAPR_DROME	Cardioacceleratory peptide receptor	12177421	Identification of G protein-coupled receptors for Drosophila PRXamide peptides, CCAP, corazonin, and AKH supports a theory of ligand- receptor coevolution.

O60921	HUS1_HUMAN	Checkpoint protein HUS1	10884395	The human checkpoint protein hRad17 interacts with the PCNA-like proteins hRad1, hHus1, and hRad9.

Q9JKN5	OLIG1_MOUSE	Oligodendrocyte transcription factor 1	11955448	Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection.

Q9SEI0	WER_ARATH	Transcription factor WER	15361138	Comprehensive identification of Arabidopsis thaliana MYB transcription factors interacting with R/B-like BHLH proteins.

P17797	VIRB7_AGRT5	Outer membrane lipoprotein virB7	2233252	Characterization of the virB operon of an Agrobacterium tumefaciens Ti plasmid: nucleotide sequence and protein analysis.

O74354	DNT1_SCHPO	Nucleolar protein dnt1	17538026	The nucleolar net1/cfi1-related protein dnt1 antagonizes the septation initiation network in fission yeast.

Q15303	ERBB4_HUMAN	Receptor tyrosine-protein kinase erbB-4	10725395	The neuregulin receptor ErbB-4 interacts with PDZ-containing proteins at neuronal synapses.

P46948	RRP41_YEAST	Exosome complex component SKI6	10465791	The yeast exosome and human PM-Scl are related complexes of 3'-->5' exonucleases.

Q9SSA5	CYP38_ARATH	Peptidyl-prolyl cis-trans isomerase CYP38, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q9ERD7	TBB3_MOUSE	Tubulin beta-3 chain	20074521	Human TUBB3 mutations perturb microtubule dynamics, kinesin interactions, and axon guidance.

P52919	NBP1_YEAST	NAP1-binding protein	16436507	The Saccharomyces cerevisiae spindle pole body (SPB) component Nbp1p is required for SPB membrane insertion and interacts with the integral membrane proteins Ndc1p and Mps2p.

Q54JH6	CMT1_DICDI	DNA (cytosine-5)-methyltransferase	16400165	Developmentally regulated DNA methylation in Dictyostelium discoideum.

O35952	GLO2_RAT	Hydroxyacylglutathione hydrolase, mitochondrial	9434774	cDNA cloning and characterization of a rat spermatogenesis-associated protein RSP29.

Q10189	SPO12_SCHPO	Mitosis-specific protein spo12	11085271	spo12 is a multicopy suppressor of mcs3 that is periodically expressed in fission yeast mitosis.

P38207	APN2_YEAST	DNA-(apurinic or apyrimidinic site) lyase 2	9765213	Identification of APN2, the Saccharomyces cerevisiae homolog of the major human AP endonuclease HAP1, and its role in the repair of abasic sites.

Q92871	PMM1_HUMAN	Phosphomannomutase 1	9070917	PMM (PMM1), the human homologue of SEC53 or yeast phosphomannomutase, is localized on chromosome 22q13.

P85259	CTX18_LACTA	M-zodatoxin-Lt8g	18215128	Cyto-insectotoxins, a novel class of cytolytic and insecticidal peptides from spider venom.

O95407	TNF6B_HUMAN	Tumor necrosis factor receptor superfamily member 6B	9872321	Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer.

Q0IH87	PAX3B_XENLA	Paired box protein Pax-3-B	17409353	The activity of Pax3 and Zic1 regulates three distinct cell fates at the neural plate border.

P47901	V1BR_HUMAN	Vasopressin V1b receptor	7929452	Molecular cloning and functional expression of a cDNA encoding the human V1b vasopressin receptor.

Q08673	SRL1_YEAST	Cell wall protein SRL1	15972461	A role for the Saccharomyces cerevisiae regulation of Ace2 and polarized morphogenesis signaling network in cell integrity.

Q9P7L2	YOSB_SCHPO	Uncharacterized protein C21C3.11	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

O60870	KIN17_HUMAN	DNA/RNA-binding protein KIN17	17045609	A tandem of SH3-like domains participates in RNA binding in KIN17, a human protein activated in response to genotoxics.

P25445	TNR6_HUMAN	Tumor necrosis factor receptor superfamily member 6	7533181	Three functional soluble forms of the human apoptosis-inducing Fas molecule are produced by alternative splicing.

P35497	DHSO1_YEAST	Sorbitol dehydrogenase 1	8125328	Cloning and sequence determination of the gene encoding sorbitol dehydrogenase from Saccharomyces cerevisiae.

P32339	HMX1_YEAST	Heme-binding protein HMX1	12840010	Regulation of intracellular heme levels by HMX1, a homologue of heme oxygenase, in Saccharomyces cerevisiae.

Q9PUB4	CP26A_CHICK	Cytochrome P450 26A1	10588879	Complementary domains of retinoic acid production and degradation in the early chick embryo.

O61122	SVKA_DICDI	Serine/threonine-protein kinase svkA	18042625	The Ste20-like kinase SvkA of Dictyostelium discoideum is essential for late stages of cytokinesis.

Q8R5I7	MYCD_RAT	Myocardin	12392995	Myocardin: a component of a molecular switch for smooth muscle differentiation.

P50875	SPT20_YEAST	Transcription factor SPT20	12446794	The novel SLIK histone acetyltransferase complex functions in the yeast retrograde response pathway.

P46964	OST2_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2	9405463	The highly conserved Stt3 protein is a subunit of the yeast oligosaccharyltransferase and forms a subcomplex with Ost3p and Ost4p.

P32746	PYRD_ARATH	Dihydroorotate dehydrogenase, mitochondrial	12372626	Plant dihydroorotate dehydrogenase differs significantly in substrate specificity and inhibition from the animal enzymes.

O14770	MEIS2_HUMAN	Homeobox protein Meis2	10764806	Three-amino acid extension loop homeodomain proteins Meis2 and TGIF differentially regulate transcription.

O74974	YQL1_SCHPO	Uncharacterized protein C1827.01c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O88498	B2L11_RAT	Bcl-2-like protein 11	9731710	BOD (Bcl-2-related ovarian death gene) is an ovarian BH3 domain- containing proapoptotic Bcl-2 protein capable of dimerization with diverse antiapoptotic Bcl-2 members.

Q9UBU2	DKK2_HUMAN	Dickkopf-related protein 2	10570958	Functional and structural diversity of the human Dickkopf gene family.

Q8WT59	FAR1_ONCGU	Fatty-acid and retinol-binding protein 1	12106870	The FAR proteins of filarial nematodes: secretion, glycosylation and lipid binding characteristics.

Q07532	IWR1_YEAST	Putative transcription factor IWR1	16554755	Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.

P23615	SPT6_YEAST	Transcription elongation factor SPT6	12934008	Transcription elongation factors repress transcription initiation from cryptic sites.

P62993	GRB2_HUMAN	Growth factor receptor-bound protein 2	8388384	Insulin stimulates association of insulin receptor substrate-1 with the protein abundant Src homology/growth factor receptor-bound protein 2.

Q9Y2X0	MED16_HUMAN	Mediator of RNA polymerase II transcription subunit 16	10198638	Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators.

O60178	NTA1_SCHPO	Protein N-terminal amidase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9ZR07	FRDA_ARATH	Frataxin, mitochondrial	15474026	Functional and molecular characterization of the frataxin homolog from Arabidopsis thaliana.

P54764	EPHA4_HUMAN	Ephrin type-A receptor 4	7898931	cDNA cloning and tissue distribution of five human EPH-like receptor protein-tyrosine kinases.

Q5FBB7	SGOL1_HUMAN	Shugoshin-like 1	16582621	Differential subcellular localizations of two human Sgo1 isoforms: implications in regulation of sister chromatid cohesion and microtubule dynamics.

Q9VU87	VPS36_DROME	Vacuolar protein-sorting-associated protein 36	17268469	bicoid RNA localization requires specific binding of an endosomal sorting complex.

P63027	VAMP2_HUMAN	Vesicle-associated membrane protein 2	1976629	Structures and chromosomal localizations of two human genes encoding synaptobrevins 1 and 2.

Q61164	CTCF_MOUSE	Transcriptional repressor CTCF	16949368	CTCF-dependent chromatin insulator is linked to epigenetic remodeling.

Q07993	XYL2_YEAST	D-xylulose reductase	10486580	Evidence that the gene YLR070c of Saccharomyces cerevisiae encodes a xylitol dehydrogenase.

P82141	DLP3_ORNAN	Defensin-like peptide 3	10417345	Solution structure of a defensin-like peptide from platypus venom.

P84264	DAH41_LITDA	Dahlein-4.1	11555873	Bioactive dahlein peptides from the skin secretions of the Australian aquatic frog Litoria dahlii: sequence determination by electrospray mass spectrometry.

P13682	ZNF35_HUMAN	Zinc finger protein 35	1572646	Structural and functional organization of the HF.10 human zinc finger gene (ZNF35) located on chromosome 3p21-p22.

Q9SRE7	CML39_ARATH	Calcium-binding protein CML39	17579812	Developmental and stimulus-induced expression patterns of Arabidopsis calmodulin-like genes CML37, CML38 and CML39.

Q92990	GLMN_HUMAN	Glomulin	11164950	Mutation of FKBP associated protein 48 (FAP48) at proline 219 disrupts the interaction with FKBP12 and FKBP52.

P32904	RM06_YEAST	54S ribosomal protein L6, mitochondrial	9151978	Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae.

Q9UBK9	UXT_HUMAN	Protein UXT	17620405	UXT is a novel and essential cofactor in the NF-kappaB transcriptional enhanceosome.

P78347	GTF2I_HUMAN	General transcription factor II-I	9334314	A multifunctional DNA-binding protein that promotes the formation of serum response factor/homeodomain complexes: identity to TFII-I.

P38969	PNT1_YEAST	Pentamidine resistance factor, mitochondrial	10490599	Mutations affecting a yeast mitochondrial inner membrane protein, pnt1p, block export of a mitochondrially synthesized fusion protein from the matrix.

P46736	BRCC3_HUMAN	Lys-63-specific deubiquitinase BRCC36	19202061	The Rap80-BRCC36 de-ubiquitinating enzyme complex antagonizes RNF8- Ubc13-dependent ubiquitination events at DNA double strand breaks.

Q12454	OCA6_YEAST	Putative tyrosine-protein phosphatase OCA6	14562095	Global analysis of protein localization in budding yeast.

Q07804	YEH1_YEAST	Sterol esterase 1	14562095	Global analysis of protein localization in budding yeast.

Q01826	SATB1_HUMAN	DNA-binding protein SATB1	1505028	A tissue-specific MAR/SAR DNA-binding protein with unusual binding site recognition.

Q02931	UTP17_YEAST	NET1-associated nuclear protein 1	12068309	A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis.

P92199	ROCK_CAEEL	Rho-associated protein kinase let-502	9042856	Caenorhabditis elegans LET-502 is related to Rho-binding kinases and human myotonic dystrophy kinase and interacts genetically with a homolog of the regulatory subunit of smooth muscle myosin phosphatase to affect cell shape.

O13837	GATA_SCHPO	4-aminobutyrate aminotransferase	17355287	A gene duplication led to specialized gamma-aminobutyrate and beta- alanine aminotransferase in yeast.

Q5EPH2	TCI1_RHIBU	Carboxypeptidase inhibitor	15561703	A carboxypeptidase inhibitor from the tick Rhipicephalus bursa. Isolation, cDNA cloning, recombinant expression, and characterization.

P28750	EXU_DROME	Maternal protein exuperantia	1752438	Protein encoded by the exuperantia gene is concentrated at sites of bicoid mRNA accumulation in Drosophila nurse cells but not in oocytes or embryos.

Q9GV36	PRSN_PIEBR	Pierisin	10971585	Purification and cloning of pierisin-2, an apoptosis-inducing protein from the cabbage butterfly, Pieris brassicae.

P97464	EXT1_MOUSE	Exostosin-1	9620772	The putative tumour suppressor EXT1 alters the expression of cell- surface heparan sulfate.

Q14296	FASTK_HUMAN	Fas-activated serine/threonine kinase	7544399	Fas-activated serine/threonine kinase (FAST) phosphorylates TIA-1 during Fas-mediated apoptosis.

P27540	ARNT_HUMAN	Aryl hydrocarbon receptor nuclear translocator	7539918	Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.

P30475	1B39_HUMAN	HLA class I histocompatibility antigen, B-39 alpha chain	8420828	Molecular analysis of HLA-B39 subtypes.

Q9ULW0	TPX2_HUMAN	Targeting protein for Xklp2	10512675	Identification of genes (SPON2 and C20orf2) differentially expressed between cancerous and noncancerous lung cells by mRNA differential display.

Q5AUX2	AXHA2_EMENI	Alpha-L-arabinofuranosidase axhA-2	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

P32836	GSP2_YEAST	GTP-binding nuclear protein GSP2/CNR2	8455603	GSP1 and GSP2, genetic suppressors of the prp20-1 mutant in Saccharomyces cerevisiae: GTP-binding proteins involved in the maintenance of nuclear organization.

P12235	ADT1_HUMAN	ADP/ATP translocase 1	10926541	Role of adenine nucleotide translocator 1 in mtDNA maintenance.

P39952	OXA1_YEAST	Mitochondrial inner membrane protein OXA1	9171337	Insertion into the mitochondrial inner membrane of a polytopic protein, the nuclear-encoded Oxa1p.

P29268	CTGF_MOUSE	Connective tissue growth factor	10082563	Fisp12/mouse connective tissue growth factor mediates endothelial cell adhesion and migration through integrin alphavbeta3, promotes endothelial cell survival, and induces angiogenesis in vivo.

Q9NRF8	PYRG2_HUMAN	CTP synthase 2	10899599	Identification of a cDNA encoding an isoform of human CTP synthetase.

O13986	YEG4_SCHPO	Uncharacterized protein C26H5.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8IZV5	RDH10_HUMAN	Retinol dehydrogenase 10	12407145	Cloning and characterization of a novel all-trans retinol short-chain dehydrogenase/reductase from the RPE.

Q86JF2	LVSB_DICDI	BEACH domain-containing protein lvsB	17488289	The BEACH protein LvsB is localized on lysosomes and postlysosomes and limits their fusion with early endosomes.

P28660	NCKP1_MOUSE	Nck-associated protein 1	14765121	Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation.

Q9CR75	TNR12_MOUSE	Tumor necrosis factor receptor superfamily member 12A	10551889	The mitogen-inducible Fn14 gene encodes a type I transmembrane protein that modulates fibroblast adhesion and migration.

Q12851	M4K2_HUMAN	Mitogen-activated protein kinase kinase kinase kinase 2	7515885	Differential expression of a novel protein kinase in human B lymphocytes. Preferential localization in the germinal center.

P38090	AGP2_YEAST	General amino acid permease AGP2	12132580	Carnitine uptake by AGP2 in yeast Saccharomyces cerevisiae is dependent on Hog1 MAP kinase pathway.

Q9UGK8	SRGEF_HUMAN	Secretion-regulating guanine nucleotide exchange factor	10571079	DelGEF, an RCC1-related protein encoded by a gene on chromosome 11p14 critical for two forms of hereditary deafness.

P42581	HMX3_MOUSE	Homeobox protein HMX3	10206974	Transcriptional antagonism between Hmx1 and Nkx2.5 for a shared DNA- binding site.

P70352	NAR5_MOUSE	Ecto-ADP-ribosyltransferase 5	8703012	Cloning and characterization of a novel membrane-associated lymphocyte NAD:arginine ADP-ribosyltransferase.

P09884	DPOLA_HUMAN	DNA polymerase alpha catalytic subunit	9518481	Functional association of poly(ADP-ribose) polymerase with DNA polymerase alpha-primase complex: a link between DNA strand break detection and DNA replication.

P53350	PLK1_HUMAN	Serine/threonine-protein kinase PLK1	18331714	sSgo1, a major splice variant of Sgo1, functions in centriole cohesion where it is regulated by Plk1.

Q09116	SPN2_SCHPO	Septin homolog spn2	15385632	Requirements of fission yeast septins for complex formation, localization, and function.

P34111	TFC3_YEAST	Transcription factor tau 138 kDa subunit	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Q9UIW2	PLXA1_HUMAN	Plexin-A1	8570614	A family of transmembrane proteins with homology to the MET- hepatocyte growth factor receptor.

P38827	SET1_YEAST	Histone-lysine N-methyltransferase, H3 lysine-4 specific	11805083	COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression.

Q2M1K9	ZN423_HUMAN	Zinc finger protein 423	10660046	OAZ uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathways.

O00231	PSD11_HUMAN	26S proteasome non-ATPase regulatory subunit 11	9119060	Molecular cloning and expression of subunit 9 of the 26S proteasome.

O74424	NU211_SCHPO	Nucleoporin nup211	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9WVB9	DVL1_RAT	Segment polarity protein dishevelled homolog DVL-1	11354832	Mapping and sequencing rat dishevelled-1: a candidate gene for cerebral ischaemic insult in a rat model of stroke.

P08861	CEL3B_HUMAN	Chymotrypsin-like elastase family member 3B	2737288	Localization and characterization of the glycosylation site of human pancreatic elastase 1.

P40540	EMC5_YEAST	ER membrane protein complex subunit 5	19325107	Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum.

O35093	TIM23_RAT	Mitochondrial import inner membrane translocase subunit Tim23	9538267	Identification of the protein import components of the rat mitochondrial inner membrane, rTIM17, rTIM23, and rTIM44.

P47875	CSRP1_RAT	Cysteine and glycine-rich protein 1	7816640	Isolation and developmental expression of a rat cDNA encoding a cysteine-rich zinc finger protein.

Q9Y7U5	RGF3_SCHPO	Rho1 guanine nucleotide exchange factor 3	16324155	Rho1-GEFs Rgf1 and Rgf2 are involved in formation of cell wall and septum, while Rgf3 is involved in cytokinesis in fission yeast.

P35429	HES2_RAT	Transcription factor HES-2	8354270	Molecular characterization of HES-2, a mammalian helix-loop-helix factor structurally related to Drosophila hairy and Enhancer of split.

O14494	LPP1_HUMAN	Lipid phosphate phosphohydrolase 1	9570154	Molecular cloning of two alternatively spliced forms of human phosphatidic acid phosphatase cDNAs that are differentially expressed in normal and tumor cells.

Q94KI8	TPC1_ARATH	Two pore calcium channel protein 1	15772667	The vacuolar Ca(2+)-activated channel TPC1 regulates germination and stomatal movement.

P53197	CDH1_YEAST	APC/C activator protein CDH1	11566880	Yeast Hct1 recognizes the mitotic cyclin Clb2 and other substrates of the ubiquitin ligase APC.

Q9QZA1	PHLA1_RAT	Pleckstrin homology-like domain family A member 1	10428057	A proline- and glutamine-rich protein promotes apoptosis in neuronal cells.

Q62639	RHEB_RAT	GTP-binding protein Rheb	8206940	Rheb, a growth factor- and synaptic activity-regulated gene, encodes a novel Ras-related protein.

Q96J02	ITCH_HUMAN	E3 ubiquitin-protein ligase Itchy homolog	14602072	The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4.

Q9QXF8	GNMT_MOUSE	Glycine N-methyltransferase	15340920	Glycine N-methyltransferases: a comparison of the crystal structures and kinetic properties of recombinant human, mouse and rat enzymes.

Q08289	CACB2_HUMAN	Voltage-dependent L-type calcium channel subunit beta-2	8494331	Cloning and characterization of a Lambert-Eaton myasthenic syndrome antigen.

Q9VHA0	SCM_DROME	Polycomb protein Scm	15280237	Requirement for sex comb on midleg protein interactions in Drosophila polycomb group repression.

P15700	UMPK_YEAST	Uridylate kinase	1655742	Molecular characterization of Saccharomyces cerevisiae URA6 gene. DNA sequence, mutagenesis analysis, and cell cycle regulation relevant to its suppression mechanism to cdc8 mutation.

O23052	Y1515_ARATH	Uncharacterized TPR repeat-containing protein At1g05150	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q9D7H4	AVPI1_MOUSE	Arginine vasopressin-induced protein 1	12356727	A novel vasopressin-induced transcript promotes MAP kinase activation and ENaC downregulation.

Q54AX5	LRRA_DICDI	Leucine-rich repeat protein lrrA	16051212	LrrA, a novel leucine-rich repeat protein involved in cytoskeleton remodeling, is required for multicellular morphogenesis in Dictyostelium discoideum.

Q16594	TAF9_HUMAN	Transcription initiation factor TFIID subunit 9	15601843	Core promoter binding by histone-like TAF complexes.

P49956	CTF18_YEAST	Chromosome transmission fidelity protein 18	11389843	Identification of RFC(Ctf18p, Ctf8p, Dcc1p): an alternative RFC complex required for sister chromatid cohesion in S. cerevisiae.

Q9LPW7	AFB3_ARATH	Protein AUXIN SIGNALING F-BOX 3	15992545	Plant development is regulated by a family of auxin receptor F box proteins.

Q16774	KGUA_HUMAN	Guanylate kinase	8663313	Cloning, characterization, and modeling of mouse and human guanylate kinases.

P46637	ARGI1_ARATH	Arginase	7770544	Nucleotide sequence of Arabidopsis thaliana arginase expressed in yeast.

P83870	PHF5A_MOUSE	PHD finger-like domain-containing protein 5A	12054543	Identification and characterization of a novel murine multigene family containing a PHD-finger-like motif.

P04439	1A03_HUMAN	HLA class I histocompatibility antigen, A-3 alpha chain	6609814	Complete nucleotide sequence of a functional class I HLA gene, HLA- A3: implications for the evolution of HLA genes.

Q9H410	DSN1_HUMAN	Kinetochore-associated protein DSN1 homolog	17981135	Human Blinkin/AF15q14 is required for chromosome alignment and the mitotic checkpoint through direct interaction with Bub1 and BubR1.

O89026	ROBO1_MOUSE	Roundabout homolog 1	19706539	Deubiquitinating enzyme USP33/VDU1 is required for Slit signaling in inhibiting breast cancer cell migration.

Q43866	INV1_ARATH	Beta-fructofuranosidase, insoluble isoenzyme CWINV1	16339783	Imaging photosynthesis in wounded leaves of Arabidopsis thaliana.

O95361	TRI16_HUMAN	Tripartite motif-containing protein 16	9817599	The novel estrogen-responsive B box protein (EBBP) gene is tamoxifen regulated in cells expressing an estrogen receptor DNA-binding domain mutant.

Q9SJT1	SAE2_ARATH	SUMO-activating enzyme subunit 2	17644626	Genetic analysis of SUMOylation in Arabidopsis: conjugation of SUMO1 and SUMO2 to nuclear proteins is essential.

Q9V464	ASF1_DROME	Histone chaperone asf1	14561777	Tousled-like kinase functions with the chromatin assembly pathway regulating nuclear divisions.

Q05466	HAT4_ARATH	Homeobox-leucine zipper protein HAT4	10477292	Shade avoidance responses are mediated by the ATHB-2 HD-zip protein, a negative regulator of gene expression.

Q15349	KS6A2_HUMAN	Ribosomal protein S6 kinase alpha-2	8141249	Human rsk isoforms: cloning and characterization of tissue-specific expression.

P53061	ZIP2_YEAST	Protein ZIP2	9590170	Zip2, a meiosis-specific protein required for the initiation of chromosome synapsis.

P36064	COXAM_YEAST	COX assembly mitochondrial protein	18443040	Cmc1p is a conserved mitochondrial twin CX(9)C protein involved in cytochrome c oxidase biogenesis.

Q8CFD1	RBM45_RAT	RNA-binding protein 45	12220514	cDNA cloning and characterization of Drb1, a new member of RRM-type neural RNA-binding protein.

P23059	NAA38_YEAST	N-alpha-acetyltransferase 38, NatC auxiliary subunit	11274203	NatC Nalpha-terminal acetyltransferase of yeast contains three subunits, Mak3p, Mak10p, and Mak31p.

P56817	BACE1_HUMAN	Beta-secretase 1	10591214	Purification and cloning of amyloid precursor protein beta-secretase from human brain.

Q13574	DGKZ_HUMAN	Diacylglycerol kinase zeta	8626588	Molecular cloning and characterization of a novel human diacylglycerol kinase zeta.

O75344	FKBP6_HUMAN	Peptidyl-prolyl cis-trans isomerase FKBP6	9782077	A novel human gene FKBP6 is deleted in Williams syndrome.

P49597	P2C56_ARATH	Protein phosphatase 2C 56	19407142	Abscisic acid inhibits type 2C protein phosphatases via the PYR/PYL family of START proteins.

Q04164	SAS_DROME	Putative epidermal cell surface receptor	1339334	The Drosophila melanogaster stranded at second (sas) gene encodes a putative epidermal cell surface receptor required for larval development.

Q9UBK9	UXT_HUMAN	Protein UXT	17635584	UXT interacts with the transcriptional repressor protein EVI1 and suppresses cell transformation.

O42601	S17B1_XENLA	Transcription factor Sox-17-beta.1	15163629	Sox17 and beta-catenin cooperate to regulate the transcription of endodermal genes.

P32769	HBS1_YEAST	Elongation factor 1 alpha-like protein	14562095	Global analysis of protein localization in budding yeast.

P46690	GASA4_ARATH	Gibberellin-regulated protein 4	9520278	Expression patterns of GASA genes in Arabidopsis thaliana: the GASA4 gene is up-regulated by gibberellins in meristematic regions.

Q84JW1	PX11E_ARATH	Peroxisomal membrane protein 11E	17220199	The PEROXIN11 protein family controls peroxisome proliferation in Arabidopsis.

B9DFG3	ISE2_ARATH	DEAD-box ATP-dependent RNA helicase ISE2, chloroplastic	11874921	Identification of a developmental transition in plasmodesmatal function during embryogenesis in Arabidopsis thaliana.

Q8RXL8	Y1689_ARATH	Uncharacterized membrane protein At1g06890	16618929	Mapping the Arabidopsis organelle proteome.

O94314	YH5A_SCHPO	Uncharacterized hydrolase C215.10	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P49756	RBM25_HUMAN	RNA-binding protein 25	18663000	Novel splicing factor RBM25 modulates Bcl-x pre-mRNA 5' splice site selection.

Q9VYB7	TPST_DROME	Protein-tyrosine sulfotransferase	16452979	Functional genomics reveals genes involved in protein secretion and Golgi organization.

Q8AXQ4	SOX12_XENLA	Transcription factor Sox-12	12890561	A novel Xenopus laevis SRY-related gene, xSox33.

Q9UST6	SPC24_SCHPO	Kinetochore protein spc24	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q99JE6	PLCB3_RAT	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3	15632121	The interaction of phospholipase C-beta3 with Shank2 regulates mGluR- mediated calcium signal.

P49677	IAA1_ARATH	Auxin-responsive protein IAA1	9342315	Protein-protein interactions among the Aux/IAA proteins.

Q32MZ4	LRRF1_HUMAN	Leucine-rich repeat flightless-interacting protein 1	9671805	TRIP: a novel double stranded RNA binding protein which interacts with the leucine rich repeat of flightless I.

O14744	ANM5_HUMAN	Protein arginine N-methyltransferase 5	9843966	Negative regulation of mitosis in fission yeast by the shk1 interacting protein skb1 and its human homolog, Skb1Hs.

Q63623	RBM16_RAT	Putative RNA-binding protein 16	9528809	A nuclear matrix protein interacts with the phosphorylated C-terminal domain of RNA polymerase II.

Q9WTP9	VAX2_MOUSE	Ventral anterior homeobox 2	11830578	The homeodomain protein Vax2 patterns the dorsoventral and nasotemporal axes of the eye.

Q9BZ72	PITM2_HUMAN	Membrane-associated phosphatidylinositol transfer protein 2	10022914	Identification of a novel family of targets of PYK2 related to Drosophila retinal degeneration B (rdgB) protein.

P25373	GLRX1_YEAST	Glutaredoxin-1	9571241	The yeast Saccharomyces cerevisiae contains two glutaredoxin genes that are required for protection against reactive oxygen species.

Q7SI97	LDH_PLABA	L-lactate dehydrogenase	12967707	Crystal structure of Plasmodium berghei lactate dehydrogenase indicates the unique structural differences of these enzymes are shared across the Plasmodium genus.

O81235	SODM_ARATH	Superoxide dismutase [Mn], mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q8GXW1	RGL2_ARATH	DELLA protein RGL2	11877383	Gibberellin regulates Arabidopsis seed germination via RGL2, a GAI/RGA-like gene whose expression is up-regulated following imbibition.

P06889	LV405_HUMAN	Ig lambda chain V-IV region MOL	3103603	Structural studies of a carbohydrate-containing immunoglobulin- lambda-light-chain amyloid-fibril protein (AL) of variable subgroup III.

Q9V4P1	ANLN_DROME	Actin-binding protein anillin	15930114	Characterization of anillin mutants reveals essential roles in septin localization and plasma membrane integrity.

Q92506	DHB8_HUMAN	Estradiol 17-beta-dehydrogenase 8	17978863	Expression in E. coli and tissue distribution of the human homologue of the mouse Ke 6 gene, 17beta-hydroxysteroid dehydrogenase type 8.

P78352	DLG4_HUMAN	Disks large homolog 4	10859302	GAKIN, a novel kinesin-like protein associates with the human homologue of the Drosophila discs large tumor suppressor in T lymphocytes.

Q03405	UPAR_HUMAN	Urokinase plasminogen activator surface receptor	8392005	An alternatively spliced variant of mRNA for the human receptor for urokinase plasminogen activator.

P54844	MAF_RAT	Transcription factor Maf	9038383	Rat maf related genes: specific expression in chondrocytes, lens and spinal cord.

P27637	BUD14_YEAST	Bud site selection protein 14	12477789	The Glc7p-interacting protein Bud14p attenuates polarized growth, pheromone response, and filamentous growth in Saccharomyces cerevisiae.

P83579	IKP2_PHYSA	Proteinase inhibitor PSKP-2	15153102	A Kazal prolyl endopeptidase inhibitor isolated from the skin of Phyllomedusa sauvagii.

P08099	OPS2_DROME	Opsin Rh2	2455230	Targeted misexpression of a Drosophila opsin gene leads to altered visual function.

O74967	VPS25_SCHPO	Vacuolar protein-sorting-associated protein 25	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P97691	FOXM1_RAT	Forkhead box protein M1	9242644	Molecular analysis of a novel winged helix protein, WIN. Expression pattern, DNA binding property, and alternative splicing within the DNA binding domain.

O08795	GLU2B_MOUSE	Glucosidase 2 subunit beta	9148925	Identification of the CD45-associated 116-kDa and 80-kDa proteins as the alpha- and beta-subunits of alpha-glucosidase II.

Q8LC03	ATB13_ARATH	Homeobox-leucine zipper protein ATHB-13	11292072	Sugar-dependent alterations in cotyledon and leaf development in transgenic plants expressing the HDZhdip gene ATHB13.

P55010	IF5_HUMAN	Eukaryotic translation initiation factor 5	8663286	Characterization of multiple mRNAs that encode mammalian translation initiation factor 5 (eIF-5).

P56559	ARL4C_HUMAN	ADP-ribosylation factor-like protein 4C	10462049	ADP-ribosylation factor (ARF)-like 4, 6, and 7 represent a subgroup of the ARF family characterization by rapid nucleotide exchange and a nuclear localization signal.

Q9US26	FTA2_SCHPO	Kinetochore protein fta2	16079914	Molecular analysis of kinetochore architecture in fission yeast.

P07237	PDIA1_HUMAN	Protein disulfide-isomerase	2846539	Characterization of the human gene for a polypeptide that acts both as the beta subunit of prolyl 4-hydroxylase and as protein disulfide isomerase.

P53541	SPO1_YEAST	Putative meiotic phospholipase SPO1	10855497	Spo1, a phospholipase B homolog, is required for spindle pole body duplication during meiosis in Saccharomyces cerevisiae.

P01355	CCKN_RAT	Cholecystokinin	8208365	Inhibition of pro-cholecystokinin (CCK) sulfation by treatment with sodium chlorate alters its processing and decreases cellular content and secretion of CCK 8.

Q63722	JAG1_RAT	Protein jagged-1	7697721	Jagged: a mammalian ligand that activates Notch1.

Q02280	KCNAE_DROME	Potassium voltage-gated channel protein eag	11517334	Control of Drosophila perineurial glial growth by interacting neurotransmitter-mediated signaling pathways.

Q8LGU6	CD27B_ARATH	Cell division cycle protein 27 homolog B	17944809	Specialization of CDC27 function in the Arabidopsis thaliana anaphase-promoting complex (APC/C).

P04818	TYSY_HUMAN	Thymidylate synthase	2987839	Nucleotide sequence of a functional cDNA for human thymidylate synthase.

P23771	GATA3_HUMAN	Trans-acting T-cell-specific transcription factor GATA-3	1871134	The human enhancer-binding protein Gata3 binds to several T-cell receptor regulatory elements.

Q9Y5S9	RBM8A_HUMAN	RNA-binding protein 8A	18026120	PYM binds the cytoplasmic exon-junction complex and ribosomes to enhance translation of spliced mRNAs.

Q84TE6	NAC22_ARATH	NAC domain-containing protein 21/22	11114891	Arabidopsis NAC1 transduces auxin signal downstream of TIR1 to promote lateral root development.

Q94KT8	COBRA_ARATH	Protein COBRA	11331607	COBRA encodes a putative GPI-anchored protein, which is polarly localized and necessary for oriented cell expansion in Arabidopsis.

O14329	YB7E_SCHPO	Uncharacterized metal transporter C16E9.14c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P11484	HSP75_YEAST	Heat shock protein SSB1	1394434	The translation machinery and 70 kd heat shock protein cooperate in protein synthesis.

O74309	SLM9_SCHPO	Histone transcription regulator slm9	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Y243	AKT3_HUMAN	RAC-gamma serine/threonine-protein kinase	19713527	The E3 ligase TRAF6 regulates Akt ubiquitination and activation.

Q9SJL7	RAX2_ARATH	Transcription factor RAX2	16463103	The MYB transcription factor superfamily of Arabidopsis: expression analysis and phylogenetic comparison with the rice MYB family.

P83255	VMFIB_VIPLE	Zinc metalloproteinase fibrolase	1926182	Purification and characterization of a fibrinogenase from Vipera lebetina (desert adder) venom.

P48059	LIMS1_HUMAN	LIM and senescent cell antigen-like-containing domain protein 1	19117955	Structural basis of focal adhesion localization of LIM-only adaptor PINCH by integrin-linked kinase.

P13942	COBA2_HUMAN	Collagen alpha-2(XI) chain	10677296	Autosomal recessive disorder otospondylomegaepiphyseal dysplasia is associated with loss-of-function mutations in the COL11A2 gene.

Q04199	CAC2_YEAST	Chromatin assembly factor 1 subunit p60	9030687	Ultraviolet radiation sensitivity and reduction of telomeric silencing in Saccharomyces cerevisiae cells lacking chromatin assembly factor-I.

Q13838	UAP56_HUMAN	Spliceosome RNA helicase BAT1	17562711	Biochemical characterization of the ATPase and helicase activity of UAP56, an essential pre-mRNA splicing and mRNA export factor.

O74476	IMB3_SCHPO	Importin subunit beta-3	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

P25573	MGR1_YEAST	Mitochondrial inner membrane i-AAA protease supercomplex subunit MGR1	16267274	A genomewide screen for petite-negative yeast strains yields a new subunit of the i-AAA protease complex.

O35324	SH21B_MOUSE	SH2 domain-containing protein 1B	9000139	EAT-2 is a novel SH2 domain containing protein that is up regulated by Ewing's sarcoma EWS/FLI1 fusion gene.

O65554	CIPK6_ARATH	CBL-interacting serine/threonine-protein kinase 6	17898163	A protein phosphorylation/dephosphorylation network regulates a plant potassium channel.

Q9V4C8	HCF_DROME	Host cell factor	12609738	Primary structure and compartmentalization of Drosophila melanogaster host cell factor.

P02836	HMEN_DROME	Segmentation polarity homeobox protein engrailed	3935318	Development of embryonic pattern in D. melanogaster as revealed by accumulation of the nuclear engrailed protein.

P23900	FPS1_YEAST	Glycerol uptake/efflux facilitator protein	7729414	Fps1, a yeast member of the MIP family of channel proteins, is a facilitator for glycerol uptake and efflux and is inactive under osmotic stress.

Q06451	TPO3_YEAST	Polyamine transporter 3	11171066	Multiple polyamine transport systems on the vacuolar membrane in yeast.

P40483	YIK8_YEAST	Putative zinc metalloproteinase YIL108W	14562095	Global analysis of protein localization in budding yeast.

Q10751	ACE_CHICK	Angiotensin-converting enzyme	7811282	Chicken lacks the testis specific isozyme of angiotensin converting enzyme found in mammals.

Q0WNX9	KRP6_ARATH	Cyclin-dependent kinase inhibitor 6	16376885	Arabidopsis KRPs have distinct inhibitory activity toward cyclin D2- associated kinases, including plant-specific B-type cyclin-dependent kinase.

P13368	7LESS_DROME	Protein sevenless	9671493	Disabled is a putative adaptor protein that functions during signaling by the sevenless receptor tyrosine kinase.

O54864	SUV91_MOUSE	Histone-lysine N-methyltransferase SUV39H1	11094092	Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression.

P42950	GSM1_YEAST	Glucose starvation modulator protein 1	16785442	Linking DNA-binding proteins to their recognition sequences by using protein microarrays.

Q13586	STIM1_HUMAN	Stromal interaction molecule 1	16208375	STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane.

Q9R0L9	MUC24_MOUSE	Sialomucin core protein 24	18227060	Regulation of myoblast motility and fusion by the CXCR4-associated sialomucin, CD164.

Q9ERP3	TRI54_MOUSE	Tripartite motif-containing protein 54	10953002	Regulation of microtubule dynamics and myogenic differentiation by MURF, a striated muscle RING-finger protein.

Q8N122	RPTOR_HUMAN	Regulatory-associated protein of mTOR	19211835	Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy.

Q55GK8	KIL1_DICDI	Membrane-associated sulfotransferase kil1	16367873	Specific host genes required for the killing of Klebsiella bacteria by phagocytes.

Q14831	GRM7_HUMAN	Metabotropic glutamate receptor 7	12052533	Characterization of three novel isoforms of the metabotropic glutamate receptor 7 (GRM7).

P25114	F264_RAT	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4	8805587	The crystal structure of the bifunctional enzyme 6-phosphofructo-2- kinase/fructose-2,6-bisphosphatase reveals distinct domain homologies.

P38970	HAL5_YEAST	Serine/threonine-protein kinase HAL5	10207057	A novel mechanism of ion homeostasis and salt tolerance in yeast: the Hal4 and Hal5 protein kinases modulate the Trk1-Trk2 potassium transporter.

Q04562	TMN2_YEAST	Transmembrane 9 superfamily member 2	18178563	Control of cellular physiology by TM9 proteins in yeast and Dictyostelium.

Q07960	RHG01_HUMAN	Rho GTPase-activating protein 1	8253717	Cloning and expression of a human CDC42 GTPase-activating protein reveals a functional SH3-binding domain.

P20273	CD22_HUMAN	B-cell receptor CD22	8627166	CD22 associates with protein tyrosine phosphatase 1C, Syk, and phospholipase C-gamma(1) upon B cell activation.

P0A9K9	SLYD_ECOLI	FKBP-type peptidyl-prolyl cis-trans isomerase slyD	19645725	The interaction of the Escherichia coli protein SlyD with nickel ions illuminates the mechanism of regulation of its peptidyl-prolyl isomerase activity.

P97836	DLGP1_RAT	Disks large-associated protein 1	10488079	Synamon, a novel neuronal protein interacting with synapse-associated protein 90/postsynaptic density-95-associated protein.

Q10725	FSDH_BURPI	Phenylserine dehydratase	12596884	Cloning, sequencing, and overexpression in Escherichia coli of a phenylserine dehydratase gene from Ralstonia pickettii PS22.

P33748	MSN2_YEAST	Zinc finger protein MSN2	8641288	The Saccharomyces cerevisiae zinc finger proteins Msn2p and Msn4p are required for transcriptional induction through the stress response element (STRE).

O74815	PPK27_SCHPO	Serine/threonine-protein kinase ppk27	15821139	Systematic deletion analysis of fission yeast protein kinases.

Q9Y4K0	LOXL2_HUMAN	Lysyl oxidase homolog 2	9079631	Regulation of a novel gene encoding a lysyl oxidase-related protein in cellular adhesion and senescence.

Q9NEU2	SDA1_CAEEL	Protein SDA1 homolog	16876152	Alterations in ribosome biogenesis cause specific defects in C. elegans hermaphrodite gonadogenesis.

Q01448	HPC2_YEAST	Histone promoter control protein 2	12524332	Defects in SPT16 or POB3 (yFACT) in Saccharomyces cerevisiae cause dependence on the Hir/Hpc pathway: polymerase passage may degrade chromatin structure.

P30099	C11B2_RAT	Cytochrome P450 11B2, mitochondrial	2350348	Molecular cloning and expression of cDNAS encoding rat aldosterone synthase: variants of cytochrome P-450(11 beta).

Q91399	ID3A_XENLA	DNA-binding protein inhibitor ID-3-A	15772131	Xenopus Id3 is required downstream of Myc for the formation of multipotent neural crest progenitor cells.

Q7RTX0	TS1R3_HUMAN	Taste receptor type 1 member 3	12892531	Taste receptor T1R3 is an essential molecule for the cellular recognition of the disaccharide trehalose.

Q9LPL4	SKP2A_ARATH	F-box protein SKP2A	18036202	SKP2A, an F-box protein that regulates cell division, is degraded via the ubiquitin pathway.

P01033	TIMP1_HUMAN	Metalloproteinase inhibitor 1	3839290	Molecular characterization and expression of the gene encoding human erythroid-potentiating activity.

Q9Y5Z9	UBIA1_HUMAN	UbiA prenyltransferase domain-containing protein 1	11314041	Isolation and characterization of the TERE1 gene, a gene down- regulated in transitional cell carcinoma of the bladder.

P11229	ACM1_HUMAN	Muscarinic acetylcholine receptor M1	3443095	Distinct primary structures, ligand-binding properties and tissue- specific expression of four human muscarinic acetylcholine receptors.

P25605	ILV6_YEAST	Acetolactate synthase small subunit, mitochondrial	8972574	Functional analysis of YCL09C: evidence for a role as the regulatory subunit of acetolactate synthase.

Q81HT3	QOX2_BACCR	Quinol oxidase subunit 2	12805383	A novel double heme substitution produces a functional bo3 variant of the quinol oxidase aa3 of Bacillus cereus. Purification and partial characterization.

Q91V37	VATO_MOUSE	V-type proton ATPase 21 kDa proteolipid subunit	11675001	Mouse Atp6f, the gene encoding the 23-kDa proteolipid of vacuolar proton translocating ATPase.

Q9WV93	HEY1_MOUSE	Hairy/enhancer-of-split related with YRPW motif protein 1	15107403	The Notch target genes Hey1 and Hey2 are required for embryonic vascular development.

P47114	YJ24_YEAST	Uncharacterized vacuolar membrane protein YJR054W	14562095	Global analysis of protein localization in budding yeast.

Q9P7G8	YLKC_SCHPO	UPF0382 membrane protein C1782.12c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O88992	C1QRF_MOUSE	C1q-related factor	9878755	Cloning and characterization of CRF, a novel C1q-related factor, expressed in areas of the brain involved in motor function.

Q9UBC9	SPRR3_HUMAN	Small proline-rich protein 3	8325635	Molecular characterization and evolution of the SPRR family of keratinocyte differentiation markers encoding small proline-rich proteins.

Q9HBA0	TRPV4_HUMAN	Transient receptor potential cation channel subfamily V member 4	11025659	OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity.

Q2PJ68	SGK1_CAEEL	Serine/threonine-protein kinase sgk-1	15068796	C. elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span.

O13809	YE0C_SCHPO	Uncharacterized FAD-binding protein C17H9.12c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9VKB9	RBGPR_DROME	Rab3 GTPase-activating protein regulatory subunit	10798391	A genome-wide search for synaptic vesicle cycle proteins in Drosophila.

P97610	SYT12_RAT	Synaptotagmin-12	8987811	Thyroid hormone-responsive genes in developing cerebellum include a novel synaptotagmin and a hairless homolog.

Q02223	TNR17_HUMAN	Tumor necrosis factor receptor superfamily member 17	8165126	The BCMA gene, preferentially expressed during B lymphoid maturation, is bidirectionally transcribed.

O43610	SPY3_HUMAN	Protein sprouty homolog 3	9458049	Sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways.

P97525	TNR8_RAT	Tumor necrosis factor receptor superfamily member 8	8982082	Cloning and characterization of a cDNA for rat CD30 homolog and chromosomal assignment of the genomic gene.

P62310	LSM3_HUMAN	U6 snRNA-associated Sm-like protein LSm3	10369684	Sm and Sm-like proteins assemble in two related complexes of deep evolutionary origin.

Q9I929	FUCL3_ANGJA	Fucolectin-3	10924498	Multiplicity, structures, and endocrine and exocrine natures of eel fucose-binding lectins.

P41544	SYS1_YEAST	Protein SYS1	15077113	Targeting of the Arf-like GTPase Arl3p to the Golgi requires N- terminal acetylation and the membrane protein Sys1p.

Q63187	ELOA1_RAT	Transcription elongation factor B polypeptide 3	8896449	The inducible elongin A elongation activation domain: structure, function and interaction with the elongin BC complex.

Q4V5A3	UNPG_DROME	Homeobox protein unplugged	8582298	Control of Drosophila tracheal branching by the novel homeodomain gene unplugged, a regulatory target for genes of the bithorax complex.

P54964	ORN_YEAST	Oligoribonuclease, mitochondrial	9933355	YNT20, a bypass suppressor of yme1 yme2, encodes a putative 3'-5' exonuclease localized in mitochondria of Saccharomyces cerevisiae.

P43026	GDF5_HUMAN	Growth/differentiation factor 5	7961761	Cartilage-derived morphogenetic proteins. New members of the transforming growth factor-beta superfamily predominantly expressed in long bones during human embryonic development.

Q13563	PKD2_HUMAN	Polycystin-2	8650545	PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein.

Q15738	NSDHL_HUMAN	Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating	10710235	Mutations in the NSDHL gene, encoding a 3beta-hydroxysteroid dehydrogenase, cause CHILD syndrome.

Q75JI3	NSF_DICDI	Vesicle-fusing ATPase	10978342	A syntaxin 7 homologue is present in Dictyostelium discoideum endosomes and controls their homotypic fusion.

Q42533	BCCP1_ARATH	Biotin carboxyl carrier protein of acetyl-CoA carboxylase 1, chloroplastic	7480350	Molecular cloning and characterization of the cDNA coding for the biotin-containing subunit of the chloroplastic acetyl-coenzyme A carboxylase.

P53254	UTP22_YEAST	U3 small nucleolar RNA-associated protein 22	14562095	Global analysis of protein localization in budding yeast.

O75190	DNJB6_HUMAN	DnaJ homolog subfamily B member 6	10954706	Identification of Mrj, a DnaJ/Hsp40 family protein, as a keratin 8/18 filament regulatory protein.

Q9DBC7	KAP0_MOUSE	cAMP-dependent protein kinase type I-alpha regulatory subunit	9852104	Identification of tethering domains for protein kinase A type Ialpha regulatory subunits on sperm fibrous sheath protein FSC1.

P08779	K1C16_HUMAN	Keratin, type I cytoskeletal 16	8595410	Novel mutations in keratin 16 gene underly focal nonepidermolytic palmoplantar keratoderma (NEPPK) in two families.

Q04958	NTE1_YEAST	Lysophospholipase NTE1	14562095	Global analysis of protein localization in budding yeast.

O15432	COPT2_HUMAN	Probable low affinity copper uptake protein 2	9207117	hCTR1: a human gene for copper uptake identified by complementation in yeast.

Q3UMB9	WAHS7_MOUSE	WASH complex subunit 7	19922875	The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex.

Q15746	MYLK_HUMAN	Myosin light chain kinase, smooth muscle	8575746	The human myosin light chain kinase (MLCK) from hippocampus: cloning, sequencing, expression, and localization to 3qcen-q21.

P83324	RIP_FLAVE	Ribosome-inactivating protein velutin	11324720	Isolation and characterization of velutin, a novel low-molecular- weight ribosome-inactivating protein from winter mushroom (Flammulina velutipes) fruiting bodies.

Q9QX74	SHAN2_RAT	SH3 and multiple ankyrin repeat domains protein 2	10964907	The calcium-independent receptor for alpha-latrotoxin from human and rodent brains interacts with members of the ProSAP/SSTRIP/Shank family of multidomain proteins.

Q99929	ASCL2_HUMAN	Achaete-scute homolog 2	8751384	Genomic cloning and localization to chromosome 11p15.5 of the human achaete-scute homolog 2 (ASCL2).

P20701	ITAL_HUMAN	Integrin alpha-L	8103515	Characterization of the CD11a (alpha L, LFA-1 alpha) integrin gene promoter.

P53834	HCH1_YEAST	Hsp90 co-chaperone HCH1	9990037	Identification of SSF1, CNS1, and HCH1 as multicopy suppressors of a Saccharomyces cerevisiae Hsp90 loss-of-function mutation.

Q9Y7R1	YCX4_SCHPO	Uncharacterized protein C2H8.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P25340	ERG4_YEAST	Delta(24(24(1)))-sterol reductase	8125337	The identification of a gene family in the Saccharomyces cerevisiae ergosterol biosynthesis pathway.

Q15714	T22D1_HUMAN	TSC22 domain family protein 1	9022669	Molecular cloning and characterization of a transcription factor for the C-type natriuretic peptide gene promoter.

O94433	YHKH_SCHPO	Uncharacterized membrane protein C660.17c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O42707	YOC5_SCHPO	L-type lectin-like domain-containing protein C4F6.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q64HY3	SP9_MOUSE	Transcription factor Sp9	15358670	Sp8 and Sp9, two closely related buttonhead-like transcription factors, regulate Fgf8 expression and limb outgrowth in vertebrate embryos.

O00264	PGRC1_HUMAN	Membrane-associated progesterone receptor component 1	9705155	Cloning and tissue expression of two putative steroid membrane receptors.

Q06820	MDM36_YEAST	Mitochondrial distribution and morphology protein 36	11907266	Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae.

Q9H0H5	RGAP1_HUMAN	Rac GTPase-activating protein 1	14744859	Human mitotic spindle-associated protein PRC1 inhibits MgcRacGAP activity toward Cdc42 during the metaphase.

Q9NPI8	FANCF_HUMAN	Fanconi anemia group F protein	11063725	The Fanconi anemia protein FANCF forms a nuclear complex with FANCA, FANCC and FANCG.

Q8BGY9	SC5A7_MOUSE	High affinity choline transporter 1	15173594	Lethal impairment of cholinergic neurotransmission in hemicholinium- 3-sensitive choline transporter knockout mice.

Q08174	PCDH1_HUMAN	Protocadherin-1	8508762	Protocadherins: a large family of cadherin-related molecules in central nervous system.

P29376	LTK_HUMAN	Leukocyte tyrosine kinase receptor	7685902	Differently spliced cDNAs of human leukocyte tyrosine kinase receptor tyrosine kinase predict receptor proteins with and without a tyrosine kinase domain and a soluble receptor protein.

Q851R2	MEL1_ORYSJ	Protein argonaute MEL1	17675402	A germ cell specific gene of the ARGONAUTE family is essential for the progression of premeiotic mitosis and meiosis during sporogenesis in rice.

Q9LSD0	RIR2C_ARATH	Ribonucleoside-diphosphate reductase small chain C	16399800	Arabidopsis ribonucleotide reductases are critical for cell cycle progression, DNA damage repair, and plant development.

Q9SS90	RGLG1_ARATH	E3 ubiquitin-protein ligase RGLG1	17586653	Ubiquitin lysine 63 chain forming ligases regulate apical dominance in Arabidopsis.

P94072	GL33_ARATH	Germin-like protein subfamily 3 member 3	10987552	Arabidopsis thaliana germin-like proteins: common and specific features point to a variety of functions.

Q60611	SATB1_MOUSE	DNA-binding protein SATB1	10716941	The MAR-binding protein SATB1 orchestrates temporal and spatial expression of multiple genes during T-cell development.

P53919	NAF1_YEAST	H/ACA ribonucleoprotein complex non-core subunit NAF1	12515383	Naf1 p is a box H/ACA snoRNP assembly factor.

P05453	ERF3_YEAST	Eukaryotic peptide chain release factor GTP-binding subunit	16809762	Tpa1p is part of an mRNP complex that influences translation termination, mRNA deadenylation, and mRNA turnover in Saccharomyces cerevisiae.

P0AEY1	MARC_ECOLI	UPF0056 inner membrane protein marC	11867724	Rapid topology mapping of Escherichia coli inner-membrane proteins by prediction and PhoA/GFP fusion analysis.

Q9VF36	ACYP2_DROME	Acylphosphatase-2	12560098	Characterization of a novel Drosophila melanogaster acylphosphatase.

Q9NEL2	SSL1_CAEEL	Helicase ssl-1	15068795	A new class of C. elegans synMuv genes implicates a Tip60/NuA4-like HAT complex as a negative regulator of Ras signaling.

P53335	PXR1_YEAST	Protein PXR1	14977919	Nucleolar protein PinX1p regulates telomerase by sequestering its protein catalytic subunit in an inactive complex lacking telomerase RNA.

P25865	UBC1_ARATH	Ubiquitin-conjugating enzyme E2 1	16339806	Genome analysis and functional characterization of the E2 and RING- type E3 ligase ubiquitination enzymes of Arabidopsis.

P35749	MYH11_HUMAN	Myosin-11	16444274	Mutations in myosin heavy chain 11 cause a syndrome associating thoracic aortic aneurysm/aortic dissection and patent ductus arteriosus.

O14276	FYV7_SCHPO	rRNA-processing protein fyv7	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P29320	EPHA3_HUMAN	Ephrin type-A receptor 3	1737782	Isolation and characterization of a novel receptor-type protein tyrosine kinase (hek) from a human pre-B cell line.

P62138	PP1A_RAT	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit	17890166	The nuclear PP1 interacting protein ZAP3 (ZAP) is a putative nucleoside kinase that complexes with SAM68, CIA, NF110/45, and HNRNP- G.

Q9P6M0	SLX4_SCHPO	Structure-specific endonuclease subunit slx4	14528010	Slx1-Slx4 are subunits of a structure-specific endonuclease that maintains ribosomal DNA in fission yeast.

Q9UQF2	JIP1_HUMAN	C-Jun-amino-terminal kinase-interacting protein 1	9933567	Genomic organization, fine-mapping, and expression of the human islet-brain 1 (IB1)/C-jun-amino-terminal kinase interacting protein-1 (JIP-1) gene.

Q9Z311	MECR_RAT	Trans-2-enoyl-CoA reductase, mitochondrial	12654921	Characterization of 2-enoyl thioester reductase from mammals: an ortholog of Ybr026p/Mrf1'p of the yeast mitochondrial fatty acid synthesis type II.

Q90Z06	PRI1A_XENLA	Prickle-like protein 1-A	12699625	The prickle-related gene in vertebrates is essential for gastrulation cell movements.

Q13547	HDAC1_HUMAN	Histone deacetylase 1	10846170	HDAC1, a histone deacetylase, forms a complex with Hus1 and Rad9, two G2/M checkpoint Rad proteins.

Q9LXV2	MYB46_ARATH	Transcription factor MYB46	16581911	Transcriptional and posttranscriptional regulation of transcription factor expression in Arabidopsis roots.

Q9UGR2	Z3H7B_HUMAN	Zinc finger CCCH domain-containing protein 7B	15047801	RoXaN, a novel cellular protein containing TPR, LD, and zinc finger motifs, forms a ternary complex with eukaryotic initiation factor 4G and rotavirus NSP3.

Q13520	AQP6_HUMAN	Aquaporin-6	8812490	cDNA cloning and gene structure of a novel water channel expressed exclusively in human kidney: evidence for a gene cluster of aquaporins at chromosome locus 12q13.

Q8LFH5	RPG1_ARATH	Protein RUPTURED POLLEN GRAIN 1	18434608	RUPTURED POLLEN GRAIN1, a member of the MtN3/saliva Gene family, is crucial for exine pattern formation and cell integrity of microspores in Arabidopsis.

Q42403	TRXH3_ARATH	Thioredoxin H3	19339505	Heat-shock and redox-dependent functional switching of an h-type Arabidopsis thioredoxin from a disulfide reductase to a molecular chaperone.

P63005	LIS1_MOUSE	Platelet-activating factor acetylhydrolase IB subunit alpha	12551946	Targeted disruption of intracellular type I platelet activating factor-acetylhydrolase catalytic subunits causes severe impairment in spermatogenesis.

Q94CC0	Y5994_ARATH	Uncharacterized protein At5g49945	16618929	Mapping the Arabidopsis organelle proteome.

P38879	NACA_YEAST	Nascent polypeptide-associated complex subunit alpha	9482879	The yeast nascent polypeptide-associated complex initiates protein targeting to mitochondria in vivo.

O70469	DOK2_MOUSE	Docking protein 2	11470823	Novel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation.

Q12049	YP045_YEAST	UPF0666 protein YPR045C	14562095	Global analysis of protein localization in budding yeast.

P52870	SC6B1_YEAST	Protein transport protein SBH1	15831493	Subunits of the translocon interact with components of the oligosaccharyl transferase complex.

Q9C5X9	HAC1_ARATH	Histone acetyltransferase HAC1	11160878	Plant orthologs of p300/CBP: conservation of a core domain in metazoan p300/CBP acetyltransferase-related proteins.

O15315	RA51B_HUMAN	DNA repair protein RAD51 homolog 2	9441753	Identification of a novel human RAD51 homolog, RAD51B.

Q91619	NODAL_XENLA	Nodal homolog	12885561	Coordination of BMP-3b and cerberus is required for head formation of Xenopus embryos.

O82352	RTNLE_ARATH	Reticulon-like protein B5	16618929	Mapping the Arabidopsis organelle proteome.

P10253	LYAG_HUMAN	Lysosomal alpha-glucosidase	7717400	Leaky splicing mutation in the acid maltase gene is associated with delayed onset of glycogenosis type II.

P30561	AHR_MOUSE	Aryl hydrocarbon receptor	12215427	Interaction with Nedd8, a ubiquitin-like protein, enhances the transcriptional activity of the aryl hydrocarbon receptor.

O14234	CCH1_SCHPO	Calcium-channel protein cch1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9FVR6	Y1222_ARATH	Uncharacterized protein At1g32220, chloroplastic	16414959	Tocopherol cyclase (VTE1) localization and vitamin E accumulation in chloroplast plastoglobule lipoprotein particles.

P47061	VPS53_YEAST	Vacuolar protein sorting-associated protein 53	10637310	Vps52p, Vps53p, and Vps54p form a novel multisubunit complex required for protein sorting at the yeast late Golgi.

Q8C208	IKZF4_MOUSE	Zinc finger protein Eos	12444977	The Ikaros family protein Eos associates with C-terminal-binding protein corepressors.

P10276	RARA_HUMAN	Retinoic acid receptor alpha	19377461	GlcNAcylation of a histone methyltransferase in retinoic-acid-induced granulopoiesis.

P46963	CTK3_YEAST	CTD kinase subunit gamma	11118453	Activation of the cyclin-dependent kinase CTDK-I requires the heterodimerization of two unstable subunits.

P21275	BMP4_MOUSE	Bone morphogenetic protein 4	14623234	Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot.

Q9P7C6	CWC23_SCHPO	Pre-mRNA-splicing factor cwc23	11884590	Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

O88269	MRP6_RAT	Multidrug resistance-associated protein 6	10692506	Transport function and hepatocellular localization of mrp6 in rat liver.

P07665	SRYB_DROME	Serendipity locus protein beta	2081456	The closely related Drosophila sry beta and sry delta zinc finger proteins show differential embryonic expression and distinct patterns of binding sites on polytene chromosomes.

O43490	PROM1_HUMAN	Prominin-1	9389720	AC133, a novel marker for human hematopoietic stem and progenitor cells.

Q9LR47	IP5P3_ARATH	Type I inositol-1,4,5-trisphosphate 5-phosphatase CVP2	10559439	Genetic regulation of vascular tissue patterning in Arabidopsis.

Q84MB2	TIF8_ARATH	Protein TIFY 8	20360743	NINJA connects the co-repressor TOPLESS to jasmonate signalling.

Q9Y2A0	T53G1_HUMAN	TP53-target gene 1 protein	9713990	Isolation of a novel TP53 target gene from a colon cancer cell line carrying a highly regulated wild-type TP53 expression system.

P34609	JIP_CAEEL	JNK-interacting protein	11738026	UNC-16, a JNK-signaling scaffold protein, regulates vesicle transport in C. elegans.

Q54QC8	SEC1_DICDI	Protein transport protein sec1	17684569	Using single loxP sites to enhance homologous recombination: ts mutants in Sec1 of Dictyostelium discoideum.

Q8SXY6	TMEDA_DROME	Transmembrane emp24 domain-containing protein bai	15327786	Drosophila p24 homologues eclair and baiser are necessary for the activity of the maternally expressed Tkv receptor during early embryogenesis.

Q60997	DMBT1_MOUSE	Deleted in malignant brain tumors 1 protein	9247472	Muclin expression in the cystic fibrosis transmembrane conductance regulator knockout mouse.

P05095	ACTNA_DICDI	Alpha-actinin A	6746725	Properties of the 120,000- and 95,000-dalton actin-binding proteins from Dictyostelium discoideum and their possible functions in assembling the cytoplasmic matrix.

O00267	SPT5H_HUMAN	Transcription elongation factor SPT5	9450929	DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs.

P54578	UBP14_HUMAN	Ubiquitin carboxyl-terminal hydrolase 14	18162577	Relative structural and functional roles of multiple deubiquitylating proteins associated with mammalian 26S proteasome.

Q9W4Y2	PDFR_DROME	PDF receptor	16242402	PDF receptor signaling in Drosophila contributes to both circadian and geotactic behaviors.

Q13625	ASPP2_HUMAN	Apoptosis-stimulating of p53 protein 2	8668206	The p53-binding protein 53BP2 also interacts with Bcl2 and impedes cell cycle progression at G2/M.

Q9Z0G0	GIPC1_MOUSE	PDZ domain-containing protein GIPC1	10318831	A PDZ protein regulates the distribution of the transmembrane semaphorin, M-SemF.

Q12189	RPIA_YEAST	Ribose-5-phosphate isomerase	8929392	Cloning and characterization of the first two genes of the non- oxidative part of the Saccharomyces cerevisiae pentose-phosphate pathway.

Q9VFS5	PP4R3_DROME	Serine/threonine-protein phosphatase 4 regulatory subunit 3	16085932	A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity.

Q4G148	GXLT1_HUMAN	Glucoside xylosyltransferase 1	19940119	Identification of glycosyltransferase 8 family members as xylosyltransferases acting on o-glucosylated notch epidermal growth factor repeats.

Q15118	PDK1_HUMAN	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial	7499431	Diversity of the pyruvate dehydrogenase kinase gene family in humans.

Q62847	ADDG_RAT	Gamma-adducin	7592723	35H, a sequence isolated as a protein kinase C binding protein, is a novel member of the adducin family.

Q80XB4	NRAP_MOUSE	Nebulin-related-anchoring protein	10320340	Molecular interactions of N-RAP, a nebulin-related protein of striated muscle myotendon junctions and intercalated disks.

P15533	TRI30_MOUSE	Tripartite motif-containing protein 30	11331580	The tripartite motif family identifies cell compartments.

Q9V730	EXT1_DROME	Exostosin-1	12586063	Cholesterol modification of hedgehog is required for trafficking and movement, revealing an asymmetric cellular response to hedgehog.

Q9UU84	MU170_SCHPO	Meiotically up-regulated gene 170 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P85171	MDGA1_RAT	MAM domain-containing glycosylphosphatidylinositol anchor protein 1	15019943	Identification and characterization of two novel brain-derived immunoglobulin superfamily members with a unique structural organization.

Q65YR8	CYTA1_DICDI	Cystatin-A1	15255188	Identification of cysteine protease inhibitors that belong to cystatin family 1 in the cellular slime mold Dictyostelium discoideum.

P09603	CSF1_HUMAN	Macrophage colony-stimulating factor 1	1791839	Expression of colony-stimulating factor-1 (CSF-1) messenger RNA in human endometrial glands during the menstrual cycle: molecular cloning of a novel transcript that predicts a cell surface form of CSF-1.

Q86T24	KAISO_HUMAN	Transcriptional regulator Kaiso	10207085	The catenin p120(ctn) interacts with Kaiso, a novel BTB/POZ domain zinc finger transcription factor.

Q9Y620	RA54B_HUMAN	DNA repair and recombination protein RAD54B	10362364	Mutations of a novel human RAD54 homologue, RAD54B, in primary cancer.

P38352	SAF1_YEAST	SCF-associated factor 1	17517885	Skp1-Cullin-F-box-dependent degradation of Aah1p requires its interaction with the F-box protein Saf1p.

Q8K443	RGS13_MOUSE	Regulator of G-protein signaling 13	12193720	RGS13 regulates germinal center B lymphocytes responsiveness to CXC chemokine ligand (CXCL)12 and CXCL13.

O94283	ERV41_SCHPO	ER-derived vesicles protein 41	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9HE10	YK92_SCHPO	UPF0645 membrane protein C20H4.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9HGP0	PVG4_SCHPO	MADS-box transcription factor pvg4	15173185	Five genes involved in biosynthesis of the pyruvylated Galbeta1,3- epitope in Schizosaccharomyces pombe N-linked glycans.

P83507	MUP_CAVPO	Major urinary protein	11972481	Purification and partial characterization of the major allergen, Cav p 1, from guinea pig Cavia porcellus.

O60840	CAC1F_HUMAN	Voltage-dependent L-type calcium channel subunit alpha-1F	16505158	X linked cone-rod dystrophy, CORDX3, is caused by a mutation in the CACNA1F gene.

Q5T447	HECD3_HUMAN	E3 ubiquitin-protein ligase HECTD3	18194665	The E3 ubiquitin ligase HECTD3 regulates ubiquitination and degradation of Tara.

P56222	PO3F2_RAT	POU domain, class 3, transcription factor 2	8276233	Spacing and orientation of bipartite DNA-binding motifs as potential functional determinants for POU domain factors.

Q9LSW8	ETFB_ARATH	Electron transfer flavoprotein subunit beta, mitochondrial	16923016	The mitochondrial electron transfer flavoprotein complex is essential for survival of Arabidopsis in extended darkness.

P43378	PTN9_HUMAN	Tyrosine-protein phosphatase non-receptor type 9	1557404	Cloning and expression of a cytosolic megakaryocyte protein-tyrosine- phosphatase with sequence homology to retinaldehyde-binding protein and yeast SEC14p.

Q9EQT6	SYT13_MOUSE	Synaptotagmin-13	11171101	Characterization of KIAA1427 protein as an atypical synaptotagmin (Syt XIII).

P18963	IRA1_YEAST	Inhibitory regulator protein IRA1	2540426	IRA1, an inhibitory regulator of the RAS-cyclic AMP pathway in Saccharomyces cerevisiae.

Q92870	APBB2_HUMAN	Amyloid beta A4 precursor protein-binding family B member 2	8855266	Association of a novel human FE65-like protein with the cytoplasmic domain of the beta-amyloid precursor protein.

P38573	UPK1B_BOVIN	Uroplakin-1b	12446744	Uroplakin IIIb, a urothelial differentiation marker, dimerizes with uroplakin Ib as an early step of urothelial plaque assembly.

Q9JJ74	RAMP1_RAT	Receptor activity-modifying protein 1	11556887	Cloning, characterization and central nervous system distribution of receptor activity modifying proteins in the rat.

Q8N4T8	CBR4_HUMAN	Carbonyl reductase family member 4	19571038	17beta-Hydroxysteroid dehydrogenase type 8 and carbonyl reductase type 4 assemble as a ketoacyl reductase of human mitochondrial FAS.

P01903	DRA_HUMAN	HLA class II histocompatibility antigen, DR alpha chain	6304715	Structure and nucleotide sequence of the heavy chain gene of HLA- DR.

P28319	CWP1_YEAST	Cell wall protein CWP1	15781460	Comprehensive proteomic analysis of Saccharomyces cerevisiae cell walls: identification of proteins covalently attached via glycosylphosphatidylinositol remnants or mild alkali-sensitive linkages.

Q6F4C6	PMN14_PINFU	Prismalin-14	15132736	Characterization of Prismalin-14, a novel matrix protein from the prismatic layer of the Japanese pearl oyster (Pinctada fucata).

P47013	DS1P1_YEAST	Dihydrosphingosine 1-phosphate phosphatase LCB3	10477278	The dihydrosphingosine-1-phosphate phosphatases of Saccharomyces cerevisiae are important regulators of cell proliferation and heat stress responses.

P11488	GNAT1_HUMAN	Guanine nucleotide-binding protein G(t) subunit alpha-1	8673138	Missense mutation in the gene encoding the alpha subunit of rod transducin in the Nougaret form of congenital stationary night blindness.

Q04493	PFD5_YEAST	Prefoldin subunit 5	9463374	A novel protein complex promoting formation of functional alpha- and gamma-tubulin.

Q8L7G0	ARFA_ARATH	Auxin response factor 1	9188533	ARF1, a transcription factor that binds to auxin response elements.

Q9P013	CWC15_HUMAN	Protein CWC15 homolog	10873569	Characterization of five novel human genes in the 11q13-q22 region.

P08425	SYFM_YEAST	Phenylalanyl-tRNA synthetase, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

O55233	CER1_MOUSE	Cerberus	9501024	Murine cerberus homologue mCer-1: a candidate anterior patterning molecule.

P35575	G6PC_HUMAN	Glucose-6-phosphatase	12093795	The catalytic center of glucose-6-phosphatase. HIS176 is the nucleophile forming the phosphohistidine-enzyme intermediate during catalysis.

P45818	ROK1_YEAST	ATP-dependent RNA helicase ROK1	12054531	Two-hybrid cloning and characterization of OSH3, a yeast oxysterol- binding protein homolog.

P11157	RIR2_MOUSE	Ribonucleoside-diphosphate reductase subunit M2	2684652	Molecular cloning and expression of the functional gene encoding the M2 subunit of mouse ribonucleotide reductase: a new dominant marker gene.

Q8I8U7	TRA1_DROME	Transcription-associated protein 1	15528408	Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions.

P21926	CD9_HUMAN	CD9 antigen	1840589	Molecular cloning of the CD9 antigen. A new family of cell surface proteins.

Q9VDZ3	SQZ_DROME	Zinc finger protein squeeze	17428824	Nab controls the activity of the zinc-finger transcription factors Squeeze and Rotund in Drosophila development.

Q9UPR3	SMG5_HUMAN	Protein SMG5	12699629	Functional conservation of the telomerase protein Est1p in humans.

Q4AE70	CARM1_RAT	Histone-arginine methyltransferase CARM1	16508003	CARM1 regulates proliferation of PC12 cells by methylating HuD.

P61810	CD5R1_RAT	Cyclin-dependent kinase 5 activator 1	8662984	Phosphorylation of the high molecular weight neurofilament protein (NF-H) by Cdk5 and p35.

Q9V931	OB57C_DROME	General odorant-binding protein 57c	12213773	Genome-wide analysis of the odorant-binding protein gene family in Drosophila melanogaster.

Q62714	DEF4_RAT	Neutrophil antibiotic peptide NP-4	7594610	Rat neutrophil defensins. Precursor structures and expression during neutrophilic myelopoiesis.

Q09189	AZR1_SCHPO	5-azacytidine resistance protein azr1	9153756	Isolation of a Schizosaccharomyces pombe gene which in high copy confers resistance to the nucleoside analogue 5-azacytidine.

Q62696	DLG1_RAT	Disks large homolog 1	15951562	Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases.

P59645	FXYD3_RAT	FXYD domain-containing ion transport regulator 3	10950925	The FXYD gene family of small ion transport regulators or channels: cDNA sequence, protein signature sequence, and expression.

Q9Y2X3	NOP58_HUMAN	Nucleolar protein 58	10925205	Isolation and characterization of a novel PDGF-induced human gene.

Q15942	ZYX_HUMAN	Zyxin	18297730	The LIM-domain protein zyxin binds the homeodomain factor Xanf1/Hesx1 and modulates its activity in the anterior neural plate of Xenopus laevis embryo.

O15321	TM9S1_HUMAN	Transmembrane 9 superfamily member 1	9332367	Cloning of a human multispanning membrane protein cDNA: evidence for a new protein family.

Q9BVK2	ALG8_HUMAN	Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase	12480927	A deficiency in dolichyl-P-glucose:Glc1Man9GlcNAc2-PP-dolichyl alpha3-glucosyltransferase defines a new subtype of congenital disorders of glycosylation.

Q14207	NPAT_HUMAN	Protein NPAT	14585971	Identification of HiNF-P, a key activator of cell cycle-controlled histone H4 genes at the onset of S phase.

P54632	1433_DICDI	14-3-3-like protein	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

Q9GZV5	WWTR1_HUMAN	WW domain-containing transcription regulator protein 1	19010321	TAZ is a coactivator for Pax8 and TTF-1, two transcription factors involved in thyroid differentiation.

O74890	SYYM_SCHPO	Tyrosyl-tRNA synthetase, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8BHK3	S36A2_MOUSE	Proton-coupled amino acid transporter 2	11959859	Functional characterization of two novel mammalian electrogenic proton-dependent amino acid cotransporters.

Q7XJ98	KATAM_ARATH	Xyloglucan galactosyltransferase KATAMARI1	12837954	The MUR3 gene of Arabidopsis encodes a xyloglucan galactosyltransferase that is evolutionarily related to animal exostosins.

Q13636	RAB31_HUMAN	Ras-related protein Rab-31	8863739	Molecular cloning of two novel rab genes from human melanocytes.

Q44340	FLGI_AGRT5	Flagellar P-ring protein	9161424	Isolation and characterisation of a linked cluster of genes from Agrobacterium tumefaciens encoding proteins involved in flagellar basal-body structure.

Q9M9E1	AB40G_ARATH	ABC transporter G family member 40	15923333	AtPDR12 contributes to lead resistance in Arabidopsis.

Q9USR9	CENPC_SCHPO	Centromere protein 3	15791413	Comparison of Dam tagging and chromatin immunoprecipitation as tools for the identification of the binding sites for S. pombe CENP-C.

Q9VV28	NPLP3_DROME	Neuropeptide-like 3	12171930	Peptidomics of the larval Drosophila melanogaster central nervous system.

Q9V3Q6	M3K7_DROME	Mitogen-activated protein kinase kinase kinase 7	14519762	Immune activation of NF-kappaB and JNK requires Drosophila TAK1.

P90648	MHCKB_DICDI	Myosin heavy chain kinase B	9115238	Identification of a protein kinase from Dictyostelium with homology to the novel catalytic domain of myosin heavy chain kinase A.

Q98SV1	SELPA_DANRE	Selenoprotein Pa	11168591	Selenium metabolism in zebrafish: multiplicity of selenoprotein genes and expression of a protein containing 17 selenocysteine residues.

Q8WVM0	TFB1M_HUMAN	Dimethyladenosine transferase 1, mitochondrial	12897151	Human mitochondrial transcription factor B1 interacts with the C- terminal activation region of h-mtTFA and stimulates transcription independently of its RNA methyltransferase activity.

O13370	DED1_SCHPO	ATP-dependent RNA helicase ded1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P34909	NOT4_YEAST	General negative regulator of transcription subunit 4	10490603	The CCR4 and CAF1 proteins of the CCR4-NOT complex are physically and functionally separated from NOT2, NOT4, and NOT5.

Q9LJX0	AB19B_ARATH	ABC transporter B family member 19	11701880	Multidrug resistance-like genes of Arabidopsis required for auxin transport and auxin-mediated development.

Q61041	NPY4R_MOUSE	Neuropeptide Y receptor type 4	8641440	Cloning and characterization of a novel receptor to pancreatic polypeptide, a member of the neuropeptide Y receptor family.

Q54IY3	CETNA_DICDI	Centrin-A	11713866	Dictyostelium centrin-related protein (DdCrp), the most divergent member of the centrin family, possesses only two EF hands and dissociates from the centrosome during mitosis.

O08583	THOC4_MOUSE	THO complex subunit 4	10786854	REF, an evolutionarily conserved family of hnRNP-like proteins, interacts with TAP/Mex67p and participates in mRNA nuclear export.

O49250	CYCLD_ANTMA	Transcription factor CYCLOIDEA	8893002	Origin of floral asymmetry in Antirrhinum.

P53283	TPO2_YEAST	Polyamine transporter 2	11171066	Multiple polyamine transport systems on the vacuolar membrane in yeast.

Q96242	CP74A_ARATH	Allene oxide synthase, chloroplastic	12766230	Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.

P31382	PMT2_YEAST	Dolichyl-phosphate-mannose--protein mannosyltransferase 2	8918452	The PMT gene family: protein O-glycosylation in Saccharomyces cerevisiae is vital.

P54274	TERF1_HUMAN	Telomeric repeat-binding factor 1	20159592	Structural basis of selective ubiquitination of TRF1 by SCFFbx4.

O75251	NDUS7_HUMAN	NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial	8938450	Assignment of the PSST subunit gene of human mitochondrial complex I to chromosome 19p13.

Q80TR4	SLIT1_MOUSE	Slit homolog 1 protein	11804571	Slit proteins prevent midline crossing and determine the dorsoventral position of major axonal pathways in the mammalian forebrain.

P28061	PSB_THEAC	Proteasome subunit beta	20019667	Interactions of PAN's C-termini with archaeal 20S proteasome and implications for the eukaryotic proteasome-ATPase interactions.

Q9HAS3	S28A3_HUMAN	Solute carrier family 28 member 3	11032837	Molecular identification and characterization of novel human and mouse concentrative Na+-nucleoside cotransporter proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib).

P77671	ALLB_ECOLI	Allantoinase	11092864	Functional expression and characterization of the two cyclic amidohydrolase enzymes, allantoinase and a novel phenylhydantoinase, from Escherichia coli.

Q28GQ2	MECR_XENTR	Trans-2-enoyl-CoA reductase, mitochondrial	18472403	A functional screen for genes involved in Xenopus pronephros development.

Q09624	LOV1_CAEEL	Location of vulva defective 1	11553327	The Caenorhabditis elegans autosomal dominant polycystic kidney disease gene homologs lov-1 and pkd-2 act in the same pathway.

Q9JL21	CCR10_MOUSE	C-C chemokine receptor type 10	10725696	Identification of the orphan receptor G-protein-coupled receptor 2 as CCR10, a specific receptor for the chemokine ESkine.

Q02936	HH_DROME	Protein hedgehog	7885476	The product of hedgehog autoproteolytic cleavage active in local and long-range signalling.

Q9VWW0	CREBB_DROME	Cyclic AMP response element-binding protein B	7651429	A Drosophila CREB/CREM homolog encodes multiple isoforms, including a cyclic AMP-dependent protein kinase-responsive transcriptional activator and antagonist.

Q80V91	DTX3_MOUSE	Protein deltex-3	11226752	Murine homologs of deltex define a novel gene family involved in vertebrate Notch signaling and neurogenesis.

Q86UE4	LYRIC_HUMAN	Protein LYRIC	15927426	Cloning and characterization of HIV-1-inducible astrocyte elevated gene-1, AEG-1.

P16188	1A30_HUMAN	HLA class I histocompatibility antigen, A-30 alpha chain	2478623	Molecular analysis of the serologically defined HLA-Aw19 antigens. A genetically distinct family of HLA-A antigens comprising A29, A31, A32, and Aw33, but probably not A30.

P17948	VGFR1_HUMAN	Vascular endothelial growth factor receptor 1	8248162	Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor.

O59707	YN4A_SCHPO	PRELI/MSF1 domain-containing protein C36.10	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P09937	SPS4_YEAST	Sporulation-specific protein 4	3540611	The SPS4 gene of Saccharomyces cerevisiae encodes a major sporulation-specific mRNA.

Q9NZB8	MOCS1_HUMAN	Molybdenum cofactor biosynthesis protein 1	9921896	Genomic structure and mutational spectrum of the bicistronic MOCS1 gene defective in molybdenum cofactor deficiency type A.

O13737	YDR2_SCHPO	Uncharacterized endoplasmic reticulum membrane protein C16E8.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q96QR8	PURB_HUMAN	Transcriptional activator protein Pur-beta	11417483	Deletions of PURA, at 5q31, and PURB, at 7p13, in myelodysplastic syndrome and progression to acute myelogenous leukemia.

O14981	BTAF1_HUMAN	TATA-binding protein-associated factor 172	9342322	Cloning of the cDNA for the TATA-binding protein-associated factorII170 subunit of transcription factor B-TFIID reveals homology to global transcription regulators in yeast and Drosophila.

Q9P2W9	STX18_HUMAN	Syntaxin-18	10788491	Syntaxin 18, a SNAP receptor that functions in the endoplasmic reticulum, intermediate compartment, and cis-Golgi vesicle trafficking.

Q03465	RPN4_YEAST	Protein RPN4	11248031	RPN4 is a ligand, substrate, and transcriptional regulator of the 26S proteasome: a negative feedback circuit.

Q9XGM8	MGAT1_ARATH	Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	8278542	Isolation of a mutant Arabidopsis plant that lacks N-acetyl glucosaminyl transferase I and is unable to synthesize Golgi-modified complex N-linked glycans.

Q80W99	CTSR3_MOUSE	Cation channel sperm-associated protein 3	16107607	Catsper3 and catsper4 encode two cation channel-like proteins exclusively expressed in the testis.

Q5VZM2	RRAGB_HUMAN	Ras-related GTP-binding protein B	7499430	Cloning of a novel family of mammalian GTP-binding proteins (RagA, RagBs, RagBl) with remote similarity to the Ras-related GTPases.

Q9NVC6	MED17_HUMAN	Mediator of RNA polymerase II transcription subunit 17	10235267	Composite co-activator ARC mediates chromatin-directed transcriptional activation.

Q15848	ADIPO_HUMAN	Adiponectin	10961870	Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages.

P40031	SPO73_YEAST	Sporulation-specific protein 73	11470404	A screen for genes required for meiosis and spore formation based on whole-genome expression.

P15157	TRYA1_HUMAN	Tryptase alpha-1	2677049	Cloning and characterization of complementary DNA for human tryptase.

P38263	VID24_YEAST	Vacuolar import and degradation protein 24	12686616	Catabolite degradation of fructose-1,6-bisphosphatase in the yeast Saccharomyces cerevisiae: a genome-wide screen identifies eight novel GID genes and indicates the existence of two degradation pathways.

Q8MLZ3	PDE5_DICDI	cGMP-dependent 3',5'-cGMP phosphodiesterase A	12429832	Identification and characterization of two unusual cGMP-stimulated phoshodiesterases in dictyostelium.

O13797	SGT2_SCHPO	Small glutamine-rich tetratricopeptide repeat-containing protein 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P0AFI5	PBP7_ECOLI	D-alanyl-D-alanine endopeptidase	7925376	Penicillin-binding protein 7/8 of Escherichia coli is a DD- endopeptidase.

Q9Z0Z3	SKP2_MOUSE	S-phase kinase-associated protein 2	10790373	Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication.

P32247	BRS3_HUMAN	Bombesin receptor subtype-3	8383682	BRS-3: a novel bombesin receptor subtype selectively expressed in testis and lung carcinoma cells.

Q9V4K2	GR43A_DROME	Putative gustatory receptor 43a	10710312	Candidate taste receptors in Drosophila.

Q920Q6	MSI2H_MOUSE	RNA-binding protein Musashi homolog 2	11588182	RNA-binding protein Musashi2: developmentally regulated expression in neural precursor cells and subpopulations of neurons in mammalian CNS.

Q04609	FOLH1_HUMAN	Glutamate carboxypeptidase 2	9375657	Molecular cloning of a peptidase against N-acetylaspartylglutamate from a rat hippocampal cDNA library.

O15355	PPM1G_HUMAN	Protein phosphatase 1G	9276438	PP2C gamma: a human protein phosphatase with a unique acidic domain.

Q8WWA0	ITLN1_HUMAN	Intelectin-1	16531507	Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action.

P26359	MSH3_SCHPO	DNA mismatch repair protein msh3	11333219	Control of GT repeat stability in Schizosaccharomyces pombe by mismatch repair factors.

Q99075	HBEGF_HUMAN	Proheparin-binding EGF-like growth factor	1840698	A heparin-binding growth factor secreted by macrophage-like cells that is related to EGF.

Q9UKU7	ACAD8_HUMAN	Isobutyryl-CoA dehydrogenase, mitochondrial	10524212	Isolation and characterisation of a cDNA encoding the precursor for a novel member of the acyl-CoA dehydrogenase gene family.

P36130	CAF4_YEAST	CCR4-associated factor 4	11113136	Characterization of CAF4 and CAF16 reveals a functional connection between the CCR4-NOT complex and a subset of SRB proteins of the RNA polymerase II holoenzyme.

Q7LDG7	GRP2_HUMAN	RAS guanyl-releasing protein 2	10918068	Characterization of RasGRP2, a plasma membrane-targeted, dual specificity Ras/Rap exchange factor.

P62263	RS14_HUMAN	40S ribosomal protein S14	3785212	Primary structure of human ribosomal protein S14 and the gene that encodes it.

P28902	GUC2A_RAT	Guanylin	1378267	Rat guanylin cDNA: characterization of the precursor of an endogenous activator of intestinal guanylate cyclase.

P20138	CD33_HUMAN	Myeloid cell surface antigen CD33	3139766	Isolation of a cDNA encoding CD33, a differentiation antigen of myeloid progenitor cells.

P55318	FOXA3_HUMAN	Hepatocyte nuclear factor 3-gamma	12695546	Transcriptional regulation of human CYP3A4 basal expression by CCAAT enhancer-binding protein alpha and hepatocyte nuclear factor-3 gamma.

Q13362	2A5G_HUMAN	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform	8617797	Identification of a novel protein phosphatase 2A regulatory subunit highly expressed in muscle.

P53176	MST27_YEAST	Multicopy suppressor of SEC21 protein 27	12925749	Suppression of coatomer mutants by a new protein family with COPI and COPII binding motifs in Saccharomyces cerevisiae.

O60064	YBB2_SCHPO	Probable mannose-1-phosphate guanyltransferase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UL01	DSE_HUMAN	Dermatan-sulfate epimerase	10679095	Identification of a gene coding for a new squamous cell carcinoma antigen recognized by the CTL.

P29512	TBB2_ARATH	Tubulin beta-2/beta-3 chain	1498609	The small genome of Arabidopsis contains at least nine expressed beta-tubulin genes.

P43132	BRE2_YEAST	COMPASS component BRE2	11805083	COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression.

Q8VZU2	SY132_ARATH	Syntaxin-132	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q9LY87	RGLG2_ARATH	E3 ubiquitin-protein ligase RGLG2	15644464	Functional analysis of the RING-type ubiquitin ligase family of Arabidopsis.

P40059	DOT6_YEAST	Transcriptional regulatory protein DOT6	19111667	A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters.

Q9JHF7	HPGDS_MOUSE	Hematopoietic prostaglandin D synthase	10824118	Structure and chromosomal localization of human and mouse genes for hematopoietic prostaglandin D synthase.

P04551	CDK1_SCHPO	Cell division control protein 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q6PHS9	CA2D2_MOUSE	Voltage-dependent calcium channel subunit alpha-2/delta-2	11487633	Ducky mouse phenotype of epilepsy and ataxia is associated with mutations in the Cacna2d2 gene and decreased calcium channel current in cerebellar Purkinje cells.

Q8N608	DPP10_HUMAN	Inactive dipeptidyl peptidase 10	12662155	Cloning and characterization of dipeptidyl peptidase 10, a new member of an emerging subgroup of serine proteases.

O14160	SYVM_SCHPO	Valyl-tRNA synthetase, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9QYR7	ACOT3_MOUSE	Acyl-coenzyme A thioesterase 3	10567408	Peroxisome proliferator-induced long chain acyl-CoA thioesterases comprise a highly conserved novel multi-gene family involved in lipid metabolism.

P36135	UTH1_YEAST	Protein UTH1	11958935	Dual cell wall/mitochondria localization of the 'SUN' family proteins.

P31384	CCR4_YEAST	Glucose-repressible alcohol dehydrogenase transcriptional effector	11889048	Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae.

O15078	CE290_HUMAN	Centrosomal protein of 290 kDa	14654843	Proteomic characterization of the human centrosome by protein correlation profiling.

Q920R4	GASP1_RAT	G-protein coupled receptor-associated sorting protein 1	11597585	A novel protein interacts with a clock-related protein, rPer1.

O14125	YEZB_SCHPO	Uncharacterized oxidoreductase C3A11.11c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P63079	GBRB3_RAT	Gamma-aminobutyric acid receptor subunit beta-3	2548852	GABAA receptor beta subunit heterogeneity: functional expression of cloned cDNAs.

O54839	EOMES_MOUSE	Eomesodermin homolog	18171685	Pivotal roles for eomesodermin during axis formation, epithelium-to- mesenchyme transition and endoderm specification in the mouse.

Q75Q41	TOM22_RAT	Mitochondrial import receptor subunit TOM22 homolog	15923182	Unfolding-resistant translocase targeting: a novel mechanism for outer mitochondrial membrane localization exemplified by the Bbeta2 regulatory subunit of protein phosphatase 2A.

Q39088	DOF34_ARATH	Dof zinc finger protein DOF3.4	10758484	Characterization of salicylic acid-responsive, Arabidopsis Dof domain proteins: overexpression of OBP3 leads to growth defects.

P33760	PEX6_YEAST	Peroxisomal ATPase PEX6	16007078	Functional role of the AAA peroxins in dislocation of the cycling PTS1 receptor back to the cytosol.

Q8SSQ0	GEFR_DICDI	Ras guanine nucleotide exchange factor R	17380187	Cyclic AMP signalling in Dictyostelium: G-proteins activate separate Ras pathways using specific RasGEFs.

P54265	DMPK_MOUSE	Myotonin-protein kinase	15598648	Myotonic dystrophy protein kinase phosphorylates phospholamban and regulates calcium uptake in cardiomyocyte sarcoplasmic reticulum.

P85070	GRAH2_RANGR	Grahamin-2	16487561	Two antimicrobial peptides from skin secretions of Rana grahami.

Q9Y5J3	HEY1_HUMAN	Hairy/enhancer-of-split related with YRPW motif protein 1	10415358	Hey genes: a novel subfamily of hairy- and enhancer of split related genes specifically expressed during mouse embryogenesis.

Q61143	TRPC6_MOUSE	Short transient receptor potential channel 6	8646775	trp, a novel mammalian gene family essential for agonist-activated capacitative Ca2+ entry.

P22057	PTGDS_RAT	Prostaglandin-H2 D-isomerase	11058225	Cellular localization of lipocalin-type prostaglandin D synthase (beta-trace) in the central nervous system of the adult rat.

Q9BUP3	HTAI2_HUMAN	Oxidoreductase HTATIP2	9482853	A cofactor, TIP30, specifically enhances HIV-1 Tat-activated transcription.

Q9Y8H5	FAD12_MORAP	Delta(12) fatty acid desaturase	10215899	Identification of delta12-fatty acid desaturase from arachidonic acid-producing Mortierella fungus by heterologous expression in the yeast Saccharomyces cerevisiae and the fungus Aspergillus oryzae.

Q7JVI3	EIF3M_DROME	Eukaryotic translation initiation factor 3 subunit M	16452979	Functional genomics reveals genes involved in protein secretion and Golgi organization.

Q14916	NPT1_HUMAN	Sodium-dependent phosphate transport protein 1	8288239	Molecular cloning of the cDNA encoding a human renal sodium phosphate transport protein and its assignment to chromosome 6p21.3-p23.

P32597	STH1_YEAST	Nuclear protein STH1/NPS1	10025404	Histone octamer transfer by a chromatin-remodeling complex.

Q5YDB6	CPL1_ARATH	RNA polymerase II C-terminal domain phosphatase-like 1	15388846	Arabidopsis C-terminal domain phosphatase-like 1 and 2 are essential Ser-5-specific C-terminal domain phosphatases.

Q06100	CGL1_COPCI	Galectin-1	8999822	Fungal galectins, sequence and specificity of two isolectins from Coprinus cinereus.

Q9H6P5	TASP1_HUMAN	Threonine aspartase 1	14636557	Taspase1: a threonine aspartase required for cleavage of MLL and proper HOX gene expression.

Q15418	KS6A1_HUMAN	Ribosomal protein S6 kinase alpha-1	12832467	Phosphorylation of p90 ribosomal S6 kinase (RSK) regulates extracellular signal-regulated kinase docking and RSK activity.

O60167	YHC3_SCHPO	ENTH domain-containing protein C19F8.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NS61	KCIP2_HUMAN	Kv channel-interacting protein 2	15358149	Protein-protein interactions of KChIP proteins and Kv4.2.

P34760	TSA1_YEAST	Peroxiredoxin TSA1	10681558	Distinct physiological functions of thiol peroxidase isoenzymes in Saccharomyces cerevisiae.

Q8GYN5	RIN4_ARATH	RPM1-interacting protein 4	11955429	RIN4 interacts with Pseudomonas syringae type III effector molecules and is required for RPM1-mediated resistance in Arabidopsis.

Q9UHY8	FEZ2_HUMAN	Fasciculation and elongation protein zeta-2	9096408	The Caenorhabditis elegans gene unc-76 and its human homologs define a new gene family involved in axonal outgrowth and fasciculation.

Q06100	CGL1_COPCI	Galectin-1	10931889	Fruiting body development in Coprinus cinereus: regulated expression of two galectins secreted by a non-classical pathway.

P53747	YN8Z_YEAST	Uncharacterized vacuolar membrane protein YNR061C	14562095	Global analysis of protein localization in budding yeast.

P35570	IRS1_RAT	Insulin receptor substrate 1	1380456	Phosphatidylinositol 3'-kinase is activated by association with IRS-1 during insulin stimulation.

P48973	CXL10_RAT	C-X-C motif chemokine 10	8798675	Interferon-inducible protein-10 involves vascular smooth muscle cell migration, proliferation, and inflammatory response.

Q06632	CFT1_YEAST	Protein CFT1	12145212	Yhh1p/Cft1p directly links poly(A) site recognition and RNA polymerase II transcription termination.

P45352	TYSY_RAT	Thymidylate synthase	9894005	Crystal structures of rat thymidylate synthase inhibited by Tomudex, a potent anticancer drug.

Q53084	PSA2_RHOER	Proteasome subunit alpha 2	9000518	Subunit topology of the Rhodococcus proteasome.

P48527	SYYM_YEAST	Tyrosyl-tRNA synthetase, mitochondrial	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

P48994	TRPL_DROME	Transient-receptor-potential-like protein	11931743	Light-regulated subcellular translocation of Drosophila TRPL channels induces long-term adaptation and modifies the light-induced current.

O00253	AGRP_HUMAN	Agouti-related protein	9311920	Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein.

Q17770	PDI2_CAEEL	Protein disulfide-isomerase 2	8760355	Baculovirus expression of two protein disulphide isomerase isoforms from Caenorhabditis elegans and characterization of prolyl 4- hydroxylases containing one of these polypeptides as their beta subunit.

Q9R1X4	TIM_MOUSE	Protein timeless homolog	10231394	A mammalian ortholog of Drosophila timeless, highly expressed in SCN and retina, forms a complex with mPER1.

Q05683	DCE2_RAT	Glutamate decarboxylase 2	8999827	Phosphorylation of serine residues 3, 6, 10, and 13 distinguishes membrane anchored from soluble glutamic acid decarboxylase 65 and is restricted to glutamic acid decarboxylase 65alpha.

Q8N3R9	MPP5_HUMAN	MAGUK p55 subfamily member 5	17584769	MPP1 links the Usher protein network and the Crumbs protein complex in the retina.

P32902	RT04_YEAST	37S ribosomal protein MRP4, mitochondrial	11278769	Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues.

Q8K5C0	GRHL2_MOUSE	Grainyhead-like protein 2 homolog	12175488	A highly conserved novel family of mammalian developmental transcription factors related to Drosophila grainyhead.

P13647	K2C5_HUMAN	Keratin, type II cytoskeletal 5	7520042	Mutations in the non-helical linker segment L1-2 of keratin 5 in patients with Weber-Cockayne epidermolysis bullosa simplex.

Q9H467	CUED2_HUMAN	CUE domain-containing protein 2	17347654	CUE domain containing 2 regulates degradation of progesterone receptor by ubiquitin-proteasome.

Q99755	PI51A_HUMAN	Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha	8955136	Type I phosphatidylinositol-4-phosphate 5-kinases are distinct members of this novel lipid kinase family.

Q9SR37	BGL23_ARATH	Beta-glucosidase 23	15919674	Activation of an ER-body-localized beta-glucosidase via a cytosolic binding partner in damaged tissues of Arabidopsis thaliana.

P32479	HIR1_YEAST	Protein HIR1	11404324	Yeast ASF1 protein is required for cell cycle regulation of histone gene transcription.

Q99N95	RM03_MOUSE	39S ribosomal protein L3, mitochondrial	11279069	Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria.

O80339	ERF82_ARATH	Ethylene-responsive transcription factor 3	10715325	Arabidopsis ethylene responsive element binding factors act as transcriptional activators or repressors of GCC box mediated gene expression.

Q9W0T5	PYX_DROME	Transient receptor potential channel pyrexia	15731759	Pyrexia is a new thermal transient receptor potential channel endowing tolerance to high temperatures in Drosophila melanogaster.

Q9UT83	MUG28_SCHPO	Meiotically up-regulated gene 28 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9FL28	FLS2_ARATH	LRR receptor-like serine/threonine-protein kinase FLS2	10911994	FLS2: an LRR receptor-like kinase involved in the perception of the bacterial elicitor flagellin in Arabidopsis.

P60164	KA111_PARVI	Potassium channel toxin alpha-KTx 11.1	10542442	A unified nomenclature for short-chain peptides isolated from scorpion venoms: alpha-KTx molecular subfamilies.

Q9UQB9	AURKC_HUMAN	Serine/threonine-protein kinase 13	10066797	Cell cycle-dependent expression and centrosome localization of a third human Aurora/Ipl1-related protein kinase, AIK3.

Q18825	BAR1_CAEEL	Beta-catenin/armadillo-related protein 1	11063687	Protruding vulva mutants identify novel loci and Wnt signaling factors that function during Caenorhabditis elegans vulva development.

P27692	SPT5_YEAST	Transcription elongation factor SPT5	1840633	SPT5, an essential gene important for normal transcription in Saccharomyces cerevisiae, encodes an acidic nuclear protein with a carboxy-terminal repeat.

Q943Q3	HS166_ORYSJ	16.6 kDa heat shock protein	15803416	Characterization of the genomic structures and selective expression profiles of nine class I small heat shock protein genes clustered on two chromosomes in rice (Oryza sativa L.).

Q86B87	MMD4_DROME	Modifier of mdg4	16286005	Identification of two proteins required for conjunction and regular segregation of achiasmate homologs in Drosophila male meiosis.

Q95RV2	CAV_DROME	Telomere-binding protein cav	12826664	Novel Drosophila heterochromatin protein 1 (HP1)/origin recognition complex-associated protein (HOAP) repeat motif in HP1/HOAP interactions and chromocenter associations.

Q8C5D8	PIAS2_MOUSE	E3 SUMO-protein ligase PIAS2	9256341	Miz1, a novel zinc finger transcription factor that interacts with Msx2 and enhances its affinity for DNA.

Q676U5	A16L1_HUMAN	Autophagy-related protein 16-1	15620219	Cloning and analysis of human Apg16L.

Q06705	CSR1_YEAST	Phosphatidylinositol transfer protein CSR1	10848624	Identification of a novel family of nonclassic yeast phosphatidylinositol transfer proteins whose function modulates phospholipase D activity and Sec14p-independent cell growth.

Q12383	TRM13_YEAST	tRNA guanosine-2'-O-methyltransferase TRM13	14562095	Global analysis of protein localization in budding yeast.

Q00897	A1AT4_MOUSE	Alpha-1-antitrypsin 1-4	11961105	Functional diversification during evolution of the murine alpha(1)- proteinase inhibitor family: role of the hypervariable reactive center loop.

Q07381	TSR1_YEAST	Ribosome biogenesis protein TSR1	15167894	The ribosomal protein Rps15p is required for nuclear exit of the 40S subunit precursors in yeast.

P18859	ATP5J_HUMAN	ATP synthase-coupling factor 6, mitochondrial	1825642	Human mitochondrial ATP synthase: cloning cDNA for the nuclear- encoded precursor of coupling factor 6.

Q8GZM7	PIF1_ARATH	Transcription factor PIF1	18591656	PIF1 directly and indirectly regulates chlorophyll biosynthesis to optimize the greening process in Arabidopsis.

P37366	CCL1_YEAST	Cyclin CCL1	11839796	Kin28 is found within TFIIH and a Kin28-Ccl1-Tfb3 trimer complex with differential sensitivities to T-loop phosphorylation.

P42844	ZIM17_YEAST	Mitochondrial protein import protein ZIM17	15383543	Zim17, a novel zinc finger protein essential for protein import into mitochondria.

Q8NFT2	STEA2_HUMAN	Metalloreductase STEAP2	12095985	Molecular cloning and characterization of STAMP1, a highly prostate specific six-trans-membrane protein that is overexpressed in prostate cancer.

P48383	SAK1_SCHPO	Protein sak1	7862141	The sak1+ gene of Schizosaccharomyces pombe encodes an RFX family DNA-binding protein that positively regulates cyclic AMP-dependent protein kinase-mediated exit from the mitotic cell cycle.

P52871	SC6B2_YEAST	Protein transport protein SEB2	8612571	A second trimeric complex containing homologs of the Sec61p complex functions in protein transport across the ER membrane of S. cerevisiae.

Q8GUM3	AAP5_ARATH	Amino acid permease 5	12148530	Low and high affinity amino acid H+-cotransporters for cellular import of neutral and charged amino acids.

Q92629	SGCD_HUMAN	Delta-sarcoglycan	8842738	Identification of a novel sarcoglycan gene at 5q33 encoding a sarcolemmal 35kDa glycoprotein.

Q08995	YP204_YEAST	Y' element ATP-dependent helicase YPR204W	9837911	Y'-Help1, a DNA helicase encoded by the yeast subtelomeric Y' element, is induced in survivors defective for telomerase.

Q8BKT7	THOC5_MOUSE	THO complex subunit 5 homolog	10597251	FMIP, a novel Fms-interacting protein, affects granulocyte/macrophage differentiation.

Q8LGE3	ARP6_ARATH	Actin-related protein 6	16141450	The nuclear actin-related protein ARP6 is a pleiotropic developmental regulator required for the maintenance of FLOWERING LOCUS C expression and repression of flowering in Arabidopsis.

Q05637	PHM6_YEAST	Phosphate metabolism protein 6	14562095	Global analysis of protein localization in budding yeast.

Q96NY9	MUS81_HUMAN	Crossover junction endonuclease MUS81	19596235	Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair.

P41889	CUT9_SCHPO	Anaphase-promoting complex subunit cut9	12477395	Proteomics analysis identifies new components of the fission and budding yeast anaphase-promoting complexes.

P34756	FAB1_YEAST	1-phosphatidylinositol-3-phosphate 5-kinase FAB1	9811604	The stress-activated phosphatidylinositol 3-phosphate 5-kinase Fab1p is essential for vacuole function in S. cerevisiae.

Q16543	CDC37_HUMAN	Hsp90 co-chaperone Cdc37	8666233	Mammalian p50Cdc37 is a protein kinase-targeting subunit of Hsp90 that binds and stabilizes Cdk4.

Q13705	AVR2B_HUMAN	Activin receptor type-2B	8161782	Expression of type II activin receptor genes during differentiation of human K562 cells and cDNA cloning of the human type IIB activin receptor.

Q62806	ZN148_RAT	Zinc finger protein 148	8943318	ZBP-89, a Kruppel-like zinc finger protein, inhibits epidermal growth factor induction of the gastrin promoter.

Q07988	YL040_YEAST	Cell wall protein YLR040C	10383953	Amino acid residues in the omega-minus region participate in cellular localization of yeast glycosylphosphatidylinositol-attached proteins.

Q07187	EM1_ARATH	Em-like protein GEA1	8492809	Two different Em-like genes are expressed in Arabidopsis thaliana seeds during maturation.

Q2TJ95	RSPO3_MOUSE	R-spondin-3	16543246	Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression.

Q99332	HPH1_YEAST	Protein HPH1	15189990	Hph1p and Hph2p, novel components of calcineurin-mediated stress responses in Saccharomyces cerevisiae.

P78413	IRX4_HUMAN	Iroquois-class homeodomain protein IRX-4	10625552	Cardiac expression of the ventricle-specific homeobox gene Irx4 is modulated by Nkx2-5 and dHand.

P69852	HSK3_YEAST	DASH complex subunit HSK3	15640796	The yeast DASH complex forms closed rings on microtubules.

Q05212	DR102_ARATH	DNA-damage-repair/toleration protein DRT102	8329681	Selection of Arabidopsis cDNAs that partially correct phenotypes of Escherichia coli DNA-damage-sensitive mutants and analysis of two plant cDNAs that appear to express UV-specific dark repair activities.

A4Q9F3	TTL10_MOUSE	Protein polyglycylase TTLL10	19524510	Evolutionary divergence of enzymatic mechanisms for posttranslational polyglycylation.

Q90Z06	PRI1A_XENLA	Prickle-like protein 1-A	16554046	Tes regulates neural crest migration and axial elongation in Xenopus.

P61088	UBE2N_HUMAN	Ubiquitin-conjugating enzyme E2 N	20061386	The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.

Q8AXB3	VGFR4_DANRE	Vascular endothelial growth factor receptor kdr-like	16617120	Distinct genetic interactions between multiple Vegf receptors are required for development of different blood vessel types in zebrafish.

O02853	PTGDS_BOVIN	Prostaglandin-H2 D-isomerase	9510973	Identification of a fertility-associated protein in bull seminal plasma as lipocalin-type prostaglandin D synthase.

Q0JA75	CADH7_ORYSJ	Cinnamyl alcohol dehydrogenase 7	19116760	FLEXIBLE CULM 1 encoding a cinnamyl-alcohol dehydrogenase controls culm mechanical strength in rice.

Q12675	ATC4_YEAST	Probable phospholipid-transporting ATPase DNF2	12221123	An essential subfamily of Drs2p-related P-type ATPases is required for protein trafficking between Golgi complex and endosomal/vacuolar system.

P33203	PRP40_YEAST	Pre-mRNA-processing protein PRP40	15020406	The yeast splicing factor Prp40p contains functional leucine-rich nuclear export signals that are essential for splicing.

Q15797	SMAD1_HUMAN	Mothers against decapentaplegic homolog 1	15647271	The integral inner nuclear membrane protein MAN1 physically interacts with the R-Smad proteins to repress signaling by the transforming growth factor-{beta} superfamily of cytokines.

Q68CP9	ARID2_HUMAN	AT-rich interactive domain-containing protein 2	15985610	PBAF chromatin-remodeling complex requires a novel specificity subunit, BAF200, to regulate expression of selective interferon- responsive genes.

Q9DEN4	FXD3A_XENLA	Forkhead box protein D3-A	11335115	Overexpression of the transcriptional repressor FoxD3 prevents neural crest formation in Xenopus embryos.

P43614	KEG1_YEAST	Beta-1,6-glucan synthesis-associated protein KEG1	18439903	Toward a comprehensive temperature-sensitive mutant repository of the essential genes of Saccharomyces cerevisiae.

Q8R107	PRLD1_MOUSE	PRELI domain-containing protein 1, mitochondrial	14640972	PRELI (protein of relevant evolutionary and lymphoid interest) is located within an evolutionarily conserved gene cluster on chromosome 5q34-q35 and encodes a novel mitochondrial protein.

P55050	FABPI_MOUSE	Fatty acid-binding protein, intestinal	1739433	The mouse intestinal fatty acid binding protein gene: nucleotide sequence, pattern of developmental and regional expression, and proposed structure of its protein product.

P60322	NANO2_MOUSE	Nanos homolog 2	12947200	Conserved role of nanos proteins in germ cell development.

P35817	BDF1_YEAST	Bromodomain-containing factor 1	7791775	Bdf1, a yeast chromosomal protein required for sporulation.

O00291	HIP1_HUMAN	Huntingtin-interacting protein 1	9147654	HIP-I: a huntingtin interacting protein isolated by the yeast two- hybrid system.

Q8MZJ8	FAR1_ACAVI	Fatty-acid and retinol-binding protein 1	12106870	The FAR proteins of filarial nematodes: secretion, glycosylation and lipid binding characteristics.

O95400	CD2B2_HUMAN	CD2 antigen cytoplasmic tail-binding protein 2	9843987	Identification of a proline-binding motif regulating CD2-triggered T lymphocyte activation.

Q14653	IRF3_HUMAN	Interferon regulatory factor 3	8524823	Identification of a member of the interferon regulatory factor family that binds to the interferon-stimulated response element and activates expression of interferon-induced genes.

Q9D3A9	TTYH1_MOUSE	Protein tweety homolog 1	17116230	Expression and evolution of the mammalian brain gene Ttyh1.

O94256	SET6_SCHPO	SET domain and MYND-type zinc finger protein 6	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q5BJ56	FXR1_XENTR	Fragile X mental retardation syndrome-related protein 1 homolog	15968590	Two members of the Fxr gene family, Fmr1 and Fxr1, are differentially expressed in Xenopus tropicalis.

Q9GZR2	REXO4_HUMAN	RNA exonuclease 4	10908561	Identification and characterization of a novel factor that regulates quinone reductase gene transcriptional activity.

Q8LDU4	RCCR_ARATH	Red chlorophyll catabolite reductase, chloroplastic	10743659	Molecular cloning, functional expression and characterization of RCC reductase, involved in chlorophyll catabolism.

Q8INB9	AKT1_DROME	RAC serine/threonine-protein kinase	9601646	Genetic analysis of protein kinase B (AKT) in Drosophila.

Q9V579	PREL_DROME	Protein preli-like	15700158	A novel family of mitochondrial proteins is represented by the Drosophila genes slmo, preli-like and real-time.

Q07157	ZO1_HUMAN	Tight junction protein ZO-1	12023291	Evidence for a functional interaction between cingulin and ZO-1 in cultured cells.

P06748	NPM_HUMAN	Nucleophosmin	12058066	The RNA binding activity of a ribosome biogenesis factor, nucleophosmin/B23, is modulated by phosphorylation with a cell cycle- dependent kinase and by association with its subtype.

P84686	SC46_TITCA	Toxin Tc46	15025998	Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

Q12460	NOP56_YEAST	Nucleolar protein 56	12068309	A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis.

P62598	ARR12_ARATH	Two-component response regulator ARR12	15173562	Type-B response regulators display overlapping expression patterns in Arabidopsis.

Q8TD23	ZN675_HUMAN	Zinc finger protein 675	11751921	A novel zinc finger protein that inhibits osteoclastogenesis and the function of tumor necrosis factor receptor-associated factor 6.

Q9VQI9	AFF4_DROME	AF4/FMR2 family member 4	8978055	Zygotic lethal mutations with maternal effect phenotypes in Drosophila melanogaster. II. Loci on the second and third chromosomes identified by P-element-induced mutations.

Q06430	GNT2B_HUMAN	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform B	8449405	Expression of the developmental I antigen by a cloned human cDNA encoding a member of a beta-1,6-N-acetylglucosaminyltransferase gene family.

Q9EPL6	MMP1B_MOUSE	Interstitial collagenase B	11113146	Identification and enzymatic characterization of two diverging murine counterparts of human interstitial collagenase (MMP-1) expressed at sites of embryo implantation.

O60229	KALRN_HUMAN	Kalirin	10023074	Duet is a novel serine/threonine kinase with Dbl-homology (DH) and pleckstrin-homology (PH) domains.

P43144	ACHA9_RAT	Neuronal acetylcholine receptor subunit alpha-9	12401316	Coexpression of alpha 9 and alpha 10 nicotinic acetylcholine receptors in rat dorsal root ganglion neurons.

P20048	SEC59_YEAST	Dolichol kinase	2657387	Sec59 encodes a membrane protein required for core glycosylation in Saccharomyces cerevisiae.

O13648	ANM3_SCHPO	Ribosomal protein arginine N-methytransferase rmt3	15175657	PRMT3 is a ribosomal protein methyltransferase that affects the cellular levels of ribosomal subunits.

O15160	RPAC1_HUMAN	DNA-directed RNA polymerases I and III subunit RPAC1	9540830	Cloning and characterization of the human RNA polymerase I subunit hRPA40.

Q14767	LTBP2_HUMAN	Latent-transforming growth factor beta-binding protein 2	8697098	Analysis of the human gene encoding latent transforming growth factor-beta-binding protein-2.

P02994	EF1A_YEAST	Elongation factor 1-alpha	9125210	Association of elongation factor 1 alpha and ribosomal protein L3 with the proline-rich region of yeast adenylyl cyclase-associated protein CAP.

P50084	BNS1_YEAST	Protein BNS1	10564265	Genetic and biochemical characterization of the yeast spo12 protein.

P48582	BRO1_YEAST	Vacuolar-sorting protein BRO1	12062418	Yeast Npi3/Bro1 is involved in ubiquitin-dependent control of permease trafficking.

Q9C9E3	TI11B_ARATH	Protein TIFY 11B	20360743	NINJA connects the co-repressor TOPLESS to jasmonate signalling.

P34164	SIP2_YEAST	SNF1 protein kinase subunit beta-2	9121458	The Snf1 protein kinase and its activating subunit, Snf4, interact with distinct domains of the Sip1/Sip2/Gal83 component in the kinase complex.

Q68KI4	NHX1_ARATH	Sodium/hydrogen exchanger 1	9990049	The Arabidopsis thaliana proton transporters, AtNhx1 and Avp1, can function in cation detoxification in yeast.

P41958	CED9_CAEEL	Apoptosis regulator ced-9	9027313	Interaction and regulation of subcellular localization of CED-4 by CED-9.

Q05123	ARP9_YEAST	Actin-like protein ARP9	10619019	Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains.

P28715	ERCC5_HUMAN	DNA repair protein complementing XP-G cells	8090225	XPG endonuclease makes the 3' incision in human DNA nucleotide excision repair.

Q8K560	OTOSP_RAT	Otospiralin	11880501	Down regulation of otospiralin, a novel inner ear protein, causes hair cell degeneration and deafness.

O15294	OGT1_HUMAN	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit	12670868	Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell- proliferation factor HCF-1.

O59747	PDF1_SCHPO	Palmitoyl-protein thioesterase-dolichyl pyrophosphate phosphatase fusion 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q4PIR3	NSE2_SCHPO	E3 SUMO-protein ligase nse2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P37198	NUP62_HUMAN	Nuclear pore glycoprotein p62	1915414	Human nucleoporin p62 and the essential yeast nuclear pore protein NSP1 show sequence homology and a similar domain organization.

P82841	BR1PA_RANPI	Brevinin-1Pa	10651828	Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens.

P70708	PADI3_RAT	Protein-arginine deiminase type-3	9192727	Isolation and molecular cloning of epidermal- and hair follicle- specific peptidylarginine deiminase (type III) from rat.

P30926	ACHB4_HUMAN	Neuronal acetylcholine receptor subunit beta-4	11450844	Characterization of the human beta4 nAChR gene and polymorphisms in CHRNA3 and CHRNB4.

P40350	ALG5_YEAST	Dolichyl-phosphate beta-glucosyltransferase	8076653	Isolation of the ALG5 locus encoding the UDP-glucose:dolichyl- phosphate glucosyltransferase from Saccharomyces cerevisiae.

Q9SMQ4	SRK2F_ARATH	Serine/threonine-protein kinase SRK2F	15292193	Identification of nine sucrose nonfermenting 1-related protein kinases 2 activated by hyperosmotic and saline stresses in Arabidopsis thaliana.

Q9C8M2	MSRB1_ARATH	Peptide methionine sulfoxide reductase B1, chloroplastic	17031545	Plant methionine sulfoxide reductase A and B multigenic families.

P83686	NB5R3_PIG	NADH-cytochrome b5 reductase 3	3967486	Gastric microsomal NADH-cytochrome b5 reductase: characterization and solubilization.

P35568	IRS1_HUMAN	Insulin receptor substrate 1	7559478	Distinct modes of interaction of SHC and insulin receptor substrate-1 with the insulin receptor NPEY region via non-SH2 domains.

Q9DCR4	EID1_MOUSE	EP300-interacting inhibitor of differentiation 1	11964378	A transcriptional inhibitor targeted by the atypical orphan nuclear receptor SHP.

P60484	PTEN_HUMAN	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	9256433	P-TEN, the tumor suppressor from human chromosome 10q23, is a dual- specificity phosphatase.

O43704	ST1B1_HUMAN	Sulfotransferase family cytosolic 1B member 1	9463486	Expression and characterization of a novel thyroid hormone-sulfating form of cytosolic sulfotransferase from human liver.

O60568	PLOD3_HUMAN	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3	9724729	Cloning and characterization of a third human lysyl hydroxylase isoform.

P02599	CALM_DICDI	Calmodulin	6087882	Structural and functional properties of calmodulin from the eukaryotic microorganism Dictyostelium discoideum.

Q69CM7	MYBPP_RAT	MYCBP-associated protein	15607946	Cod106, a novel synaptic protein expressed in sensory hair cells of the inner ear and in CNS neurons.

Q8VIM5	MYCD_MOUSE	Myocardin	12640126	Myocardin is a critical serum response factor cofactor in the transcriptional program regulating smooth muscle cell differentiation.

Q08220	GSHB_YEAST	Glutathione synthetase	9512666	Molecular identification of glutathione synthetase (GSH2) gene from Saccharomyces cerevisiae.

P26359	MSH3_SCHPO	DNA mismatch repair protein msh3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P94217	SLAP2_BACAN	S-layer protein EA1	9106206	Molecular characterization of the Bacillus anthracis main S-layer component: evidence that it is the major cell-associated antigen.

Q9LPR4	LEU11_ARATH	2-isopropylmalate synthase 1, chloroplastic	17189332	Two Arabidopsis genes (IPMS1 and IPMS2) encode isopropylmalate synthase, the branchpoint step in the biosynthesis of leucine.

Q9UUI2	YIYC_SCHPO	Uncharacterized protein C22F8.12c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NXV2	KCTD5_HUMAN	BTB/POZ domain-containing protein KCTD5	18573101	KCTD5, a putative substrate adaptor for cullin3 ubiquitin ligases.

Q63425	PRAX_RAT	Periaxin	8155317	Periaxin, a novel protein of myelinating Schwann cells with a possible role in axonal ensheathment.

Q9UD71	PPR1B_HUMAN	Protein phosphatase 1 regulatory subunit 1B	10604473	Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons.

Q923S6	NEU1A_MOUSE	Neuralized-like protein 1A	11481456	Ethanol hypersensitivity and olfactory discrimination defect in mice lacking a homolog of Drosophila neuralized.

Q54Z13	VATG_DICDI	V-type proton ATPase subunit G	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q24211	STNA_DROME	Protein stoned-A	11160392	Interaction of stoned and synaptotagmin in synaptic vesicle endocytosis.

Q9JM96	BORG4_MOUSE	Cdc42 effector protein 4	10490598	The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins.

Q9W4Q9	INSL7_DROME	Probable insulin-like peptide 7	11250149	An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control.

O75154	RFIP3_HUMAN	Rab11 family-interacting protein 3	17007872	Structural basis for Rab11-mediated recruitment of FIP3 to recycling endosomes.

Q5Y808	ROP4_TOXGO	Rhoptry protein 4	15470260	The Toxoplasma gondii rhoptry protein rop4 is secreted into the parasitophorous vacuole and becomes phosphorylated in infected cells.

Q9UT29	YKGC_SCHPO	Uncharacterized protein C8F11.08c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q18688	HSP90_CAEEL	Heat shock protein 90	10790386	A transmembrane guanylyl cyclase (DAF-11) and Hsp90 (DAF-21) regulate a common set of chemosensory behaviors in Caenorhabditis elegans.

Q9JKE8	TR110_RAT	Taste receptor type 2 member 110	10761934	A novel family of mammalian taste receptors.

Q05549	HRQ1_YEAST	Putative ATP-dependent helicase HRQ1	14562095	Global analysis of protein localization in budding yeast.

Q6IUP1	SOLH1_MOUSE	Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1	16690745	Oogenesis requires germ cell-specific transcriptional regulators Sohlh1 and Lhx8.

Q9ZT17	AGP3_ARATH	Classical arabinogalactan protein 3	12177459	Using genomic resources to guide research directions. The arabinogalactan protein gene family as a test case.

O94261	FTA3_SCHPO	Kinetochore protein fta3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P38983	RSSA_RAT	40S ribosomal protein SA	8119397	Structural determination and characterization of a 40 kDa protein isolated from rat 40 S ribosomal subunit.

P17516	AK1C4_HUMAN	Aldo-keto reductase family 1 member C4	8172617	Molecular cloning of two human liver 3 alpha- hydroxysteroid/dihydrodiol dehydrogenase isoenzymes that are identical with chlordecone reductase and bile-acid binder.

Q946J8	LHP1_ARATH	Chromo domain-containing protein LHP1	16549797	LHP1, the Arabidopsis homologue of HETEROCHROMATIN PROTEIN1, is required for epigenetic silencing of FLC.

P50221	MEOX1_HUMAN	Homeobox protein MOX-1	7987315	Isolation of a diverged homeobox gene, MOX1, from the BRCA1 region on 17q21 by solution hybrid capture.

Q9Y7V0	MU117_SCHPO	Meiotically up-regulated gene 117 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P53844	PDR17_YEAST	Phosphatidylinositol transfer protein PDR17	9890948	PDR16 and PDR17, two homologous genes of Saccharomyces cerevisiae, affect lipid biosynthesis and resistance to multiple drugs.

P19807	HNM1_YEAST	Choline transport protein	2203793	Primary structure of the yeast choline transport gene and regulation of its expression.

Q12926	ELAV2_HUMAN	ELAV-like protein 2	8158249	Mammalian homologs of Drosophila ELAV localized to a neuronal subset can bind in vitro to the 3' UTR of mRNA encoding the Id transcriptional repressor.

Q03016	GIP3_YEAST	GLC7-interacting protein 3	14562095	Global analysis of protein localization in budding yeast.

O76090	BEST1_HUMAN	Bestrophin-1	9662395	Identification of the gene responsible for Best macular dystrophy.

Q8QZY1	EIF3L_MOUSE	Eukaryotic translation initiation factor 3 subunit L	17581632	Reconstitution reveals the functional core of mammalian eIF3.

O08774	RGS12_RAT	Regulator of G-protein signaling 12	9651375	GTPase activating specificity of RGS12 and binding specificity of an alternatively spliced PDZ (PSD-95/Dlg/ZO-1) domain.

Q8IMX7	MIRO_DROME	Mitochondrial Rho GTPase	16717129	Axonal transport of mitochondria requires milton to recruit kinesin heavy chain and is light chain independent.

Q13972	RGRF1_HUMAN	Ras-specific guanine nucleotide-releasing factor 1	10373510	Ras-specific exchange factor GRF: oligomerization through its Dbl homology domain and calcium-dependent activation of Raf.

Q76PC7	IF3M_SCHPO	Probable translation initiation factor, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q7JXV9	VPS25_DROME	Vacuolar protein-sorting-associated protein 25	16256743	The Drosophila tumor suppressor vps25 prevents nonautonomous overproliferation by regulating notch trafficking.

Q99683	M3K5_HUMAN	Mitogen-activated protein kinase kinase kinase 5	11298454	HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell.

Q64268	HEP2_RAT	Heparin cofactor 2	8286422	Secondary thrombin-binding site, glycosaminoglycan binding domain and reactive center region of leuserpin-2 are strongly conserved in mammalian species.

Q84JU6	HOS1_ARATH	E3 ubiquitin-protein ligase HOS1	16702557	The negative regulator of plant cold responses, HOS1, is a RING E3 ligase that mediates the ubiquitination and degradation of ICE1.

P27810	KTR1_YEAST	Alpha-1,2 mannosyltransferase KTR1	9020857	Ktr1p is an alpha-1,2-mannosyltransferase of Saccharomyces cerevisiae. Comparison of the enzymic properties of soluble recombinant Ktr1p and Kre2p/Mnt1p produced in Pichia pastoris.

P08630	BTKL_DROME	Tyrosine-protein kinase Btk29A	9660966	SRC64 regulates the localization of a Tec-family kinase required for Drosophila ring canal growth.

Q38827	IAA9_ARATH	Auxin-responsive protein IAA9	11115889	Aux/IAA proteins are phosphorylated by phytochrome in vitro.

O46106	NOI_DROME	Splicing factor 3A subunit 3	9528755	Multiple developmental requirements of noisette, the Drosophila homolog of the U2 snRNP-associated polypeptide SP3a60.

Q9Z0M4	MCP_RAT	Membrane cofactor protein	15215199	Rat membrane cofactor protein (MCP; CD46) is expressed only in the acrosome of developing and mature spermatozoa and mediates binding to immobilized activated C3.

Q8S8I4	EPF1_ARATH	Protein EPIDERMAL PATTERNING FACTOR 1	17639078	The secretory peptide gene EPF1 enforces the stomatal one-cell- spacing rule.

Q9UHW9	S12A6_HUMAN	Solute carrier family 12 member 6	10187864	Cloning, characterization, and chromosomal location of a novel human K+-Cl- cotransporter.

P58434	CYO2_VIOOD	Cycloviolacin-O2	12477048	Cyclotides: a novel type of cytotoxic agents.

Q09815	PPK5_SCHPO	Serine/threonine-protein kinase ppk5	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P41940	MPG1_YEAST	Mannose-1-phosphate guanyltransferase	11055399	Defect in cell wall integrity of the yeast Saccharomyces cerevisiae caused by a mutation of the GDP-mannose pyrophosphorylase gene VIG9.

Q9H3H5	GPT_HUMAN	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	12872255	Deficiency of UDP-GlcNAc:dolichol phosphate N-acetylglucosamine-1 phosphate transferase (DPAGT1) causes a novel congenital disorder of glycosylation type Ij.

Q7K5N4	CALYP_DROME	Ubiquitin carboxyl-terminal hydrolase calypso	20436459	Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB.

Q13794	APR_HUMAN	Phorbol-12-myristate-13-acetate-induced protein 1	15705586	Involvement of Noxa in cellular apoptotic responses to interferon, double-stranded RNA, and virus infection.

Q04749	AVO2_YEAST	Target of rapamycin complex 2 subunit AVO2	12408816	Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control.

Q9FN37	PSKR2_ARATH	Phytosulfokine receptor 2	17989228	Tyrosine-sulfated glycopeptide involved in cellular proliferation and expansion in Arabidopsis.

Q06648	GIC2_YEAST	GTPase-interacting component 2	9367980	Novel Cdc42-binding proteins Gic1 and Gic2 control cell polarity in yeast.

P54707	AT12A_HUMAN	Potassium-transporting ATPase alpha chain 2	8838794	Genomic organization of the human ATP1AL1 gene encoding a ouabain- sensitive H,K-ATPase.

Q08227	INP54_YEAST	Inositol-1,4,5-trisphosphate 5-phosphatase 4	10660045	Phosphatidylinositol 4,5-bisphosphate functions as a second messenger that regulates cytoskeleton-plasma membrane adhesion.

P11884	ALDH2_RAT	Aldehyde dehydrogenase, mitochondrial	1898068	Purification and characterization of catalytically active precursor of rat liver mitochondrial aldehyde dehydrogenase expressed in Escherichia coli.

P00742	FA10_HUMAN	Coagulation factor X	6587384	Characterization of a cDNA coding for human factor X.

P84886	CURVA_LACCU	Bacteriocin curvaticin	16244793	Purification and characterization of curvaticin L442, a bacteriocin produced by Lactobacillus curvatus L442.

P15619	SRYC_DROME	Serendipity locus protein H-1	3141791	sry h-1, a new Drosophila melanogaster multifingered protein gene showing maternal and zygotic expression.

O55137	ACOT1_MOUSE	Acyl-coenzyme A thioesterase 1	10567408	Peroxisome proliferator-induced long chain acyl-CoA thioesterases comprise a highly conserved novel multi-gene family involved in lipid metabolism.

P17105	IP3KA_RAT	Inositol-trisphosphate 3-kinase A	2176078	Cloning and expression in Escherichia coli of a rat brain cDNA encoding a Ca2+/calmodulin-sensitive inositol 1,4,5-trisphosphate 3- kinase.

P36122	BCH2_YEAST	Protein BCH2	14562095	Global analysis of protein localization in budding yeast.

Q03898	FIN1_YEAST	Filament protein FIN1	11929974	The Saccharomyces cerevisiae Fin1 protein forms cell cycle-specific filaments between spindle pole bodies.

Q9NS85	CAH10_HUMAN	Carbonic anhydrase-related protein 10	11311946	cDNA sequence of human carbonic anhydrase-related protein, CA-RP X: mRNA expressions of CA-RP X and XI in human brain.

Q8K1P8	MOT8_RAT	Monocarboxylate transporter 8	12871948	Identification of monocarboxylate transporter 8 as a specific thyroid hormone transporter.

Q9NZ71	RTEL1_HUMAN	Regulator of telomere elongation helicase 1	18957201	RTEL1 maintains genomic stability by suppressing homologous recombination.

Q9FZ80	SOT17_ARATH	Sulfotransferase 17	15358770	Desulfoglucosinolate sulfotransferases from Arabidopsis thaliana catalyze the final step in the biosynthesis of the glucosinolate core structure.

Q9CAJ0	P2C16_ARATH	Protein phosphatase 2C 16	19898420	A gate-latch-lock mechanism for hormone signalling by abscisic acid receptors.

P0A6L0	DEOC_ECOLI	Deoxyribose-phosphate aldolase	6749498	The primary structure of Escherichia coli K12 2-deoxyribose 5- phosphate aldolase. Nucleotide sequence of the deoC gene and the amino acid sequence of the enzyme.

P32458	CDC11_YEAST	Cell division control protein 11	9813094	Polymerization of purified yeast septins: evidence that organized filament arrays may not be required for septin function.

P39877	PA2G5_HUMAN	Calcium-dependent phospholipase A2	8300559	Cloning and recombinant expression of a novel human low molecular weight Ca(2+)-dependent phospholipase A2.

P40037	HMF1_YEAST	Protein HMF1	11442631	A member of the YER057c/yjgf/Uk114 family links isoleucine biosynthesis and intact mitochondria maintenance in Saccharomyces cerevisiae.

O14417	MAD2_SCHPO	Mitotic spindle checkpoint component mad2	9223296	The Schizosaccharomyces pombe spindle checkpoint protein mad2p blocks anaphase and genetically interacts with the anaphase-promoting complex.

P41212	ETV6_HUMAN	Transcription factor ETV6	12588862	The human L(3)MBT Polycomb group protein is a transcriptional repressor and interacts physically and functionally with TEL (ETV6).

Q9JKM5	S1PR5_RAT	Sphingosine 1-phosphate receptor 5	10799507	Characterization of a novel sphingosine 1-phosphate receptor, Edg- 8.

Q9M8S6	SKOR_ARATH	Potassium channel SKOR	9741629	Identification and disruption of a plant shaker-like outward channel involved in K+ release into the xylem sap.

Q9LKW9	NHX7_ARATH	Sodium/hydrogen exchanger 7	10823923	The Arabidopsis thaliana salt tolerance gene SOS1 encodes a putative Na(+)/H(+) antiporter.

Q5DX34	RPGRH_CAEEL	X-linked retinitis pigmentosa GTPase regulator homolog	15843430	Genetic analysis of lysosomal trafficking in Caenorhabditis elegans.

Q17P71	T23O_AEDAE	Tryptophan 2,3-dioxygenase	17212352	Biochemical mechanisms leading to tryptophan 2,3-dioxygenase activation.

P62879	GBB2_HUMAN	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2	16498633	Ataxin 10 induces neuritogenesis via interaction with G-protein beta2 subunit.

Q3E846	YM244_YEAST	Uncharacterized protein YMR244C-A	14562095	Global analysis of protein localization in budding yeast.

Q9EP80	PICK1_RAT	PRKCA-binding protein	10340301	The protein kinase C alpha binding protein PICK1 interacts with short but not long form alternative splice variants of AMPA receptor subunits.

P97570	PA2G6_RAT	85 kDa calcium-independent phospholipase A2	9111008	Pancreatic islets express a Ca2+-independent phospholipase A2 enzyme that contains a repeated structural homologous to the integral membrane protein binding domain of ankyrin.

Q16825	PTN21_HUMAN	Tyrosine-protein phosphatase non-receptor type 21	7519780	Src kinase associates with a member of a distinct subfamily of protein-tyrosine phosphatases containing an ezrin-like domain.

Q810B3	BSH_MOUSE	Brain-specific homeobox protein homolog	17353277	Cloning and functional analysis of hypothalamic homeobox gene Bsx1a and its isoform, Bsx1b.

Q12153	SSF2_YEAST	Ribosome biogenesis protein SSF2	7748491	An essential gene pair in Saccharomyces cerevisiae with a potential role in mating.

Q9C0Z9	RPC9_SCHPO	DNA-directed RNA polymerase III subunit rpc9	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q92328	MDM12_YEAST	Mitochondrial distribution and morphology protein 12	17410204	The morphology proteins Mdm12/Mmm1 function in the major beta-barrel assembly pathway of mitochondria.

Q9NS64	RPRM_HUMAN	Protein reprimo	10930422	Reprimo, a new candidate mediator of the p53-mediated cell cycle arrest at the G2 phase.

O44249	PRP1_MANSE	Phenoloxidase subunit 1	10436935	Immulectin, an inducible C-type lectin from an insect, Manduca sexta, stimulates activation of plasma prophenol oxidase.

Q12400	TRM10_YEAST	tRNA (guanine-N(1)-)-methyltransferase TRM10	14562095	Global analysis of protein localization in budding yeast.

Q9UGM6	SYWM_HUMAN	Tryptophanyl-tRNA synthetase, mitochondrial	10828066	Identification and characterization of human mitochondrial tryptophanyl-tRNA synthetase.

Q9SY65	ASK18_ARATH	SKP1-like protein 18	14749489	Expression and interaction analysis of Arabidopsis Skp1-related genes.

Q92750	TAF4B_HUMAN	Transcription initiation factor TFIID subunit 4B	10849440	Interaction of TAFII105 with selected p65/RelA dimers is associated with activation of subset of NF-kappa B genes.

P48145	NPBW1_HUMAN	Neuropeptides B/W receptor type 1	12401809	Identification of natural ligands for the orphan G protein-coupled receptors GPR7 and GPR8.

Q9UIG0	BAZ1B_HUMAN	Tyrosine-protein kinase BAZ1B	11124022	Structure of the PHD zinc finger from human Williams-Beuren syndrome transcription factor.

P22681	CBL_HUMAN	E3 ubiquitin-protein ligase CBL	7657591	Tyrosine phosphorylation of the c-cbl proto-oncogene protein product and association with epidermal growth factor (EGF) receptor upon EGF stimulation.

Q9I8A3	HEY1_XENLA	Hairy/enhancer-of-split related with YRPW motif protein 1	16818449	The Notch-effector HRT1 gene plays a role in glomerular development and patterning of the Xenopus pronephros anlagen.

P54107	CRIS1_HUMAN	Cysteine-rich secretory protein 1	8543280	Analysis of the human acidic epididymal glycoprotein-like molecule: isolation of cDNA and tissue localization.

Q9NY64	GTR8_HUMAN	Solute carrier family 2, facilitated glucose transporter member 8	10671487	GLUTX1, a novel mammalian glucose transporter expressed in the central nervous system and insulin-sensitive tissues.

Q9W5P1	MED21_DROME	Mediator of RNA polymerase II transcription subunit 21	15477388	A high resolution protein interaction map of the yeast Mediator complex.

Q8VI82	FGF23_RAT	Fibroblast growth factor 23	17992255	The parathyroid is a target organ for FGF23 in rats.

Q92626	PXDN_HUMAN	Peroxidasin homolog	11103812	A novel melanoma gene (MG50) encoding the interleukin 1 receptor antagonist and six epitopes recognized by human cytolytic T lymphocytes.

Q9H239	MMP28_HUMAN	Matrix metalloproteinase-28	11121398	Epilysin, a novel human matrix metalloproteinase (MMP-28) expressed in testis and keratinocytes and in response to injury.

P01854	IGHE_HUMAN	Ig epsilon chain C region	6300763	Molecular cloning and nucleotide sequencing of human immunoglobulin epsilon chain cDNA.

O95833	CLIC3_HUMAN	Chloride intracellular channel protein 3	9880541	Molecular cloning and characterization of a mitogen-activated protein kinase-associated intracellular chloride channel.

Q06497	ANT1_YEAST	Peroxisomal adenine nucleotide transporter 1	11566870	Identification and functional reconstitution of the yeast peroxisomal adenine nucleotide transporter.

O00429	DNM1L_HUMAN	Dynamin-1-like protein	9570752	Identification and functional characterization of a novel human protein highly related to the yeast dynamin-like GTPase Vps1p.

P68036	UB2L3_HUMAN	Ubiquitin-conjugating enzyme E2 L3	8563171	A human ubiquitin conjugating enzyme, L-UBC, maps in the Alzheimer's disease locus on chromosome 14q24.3.

Q5VT25	MRCKA_HUMAN	Serine/threonine-protein kinase MRCK alpha	11283256	Intermolecular and intramolecular interactions regulate catalytic activity of myotonic dystrophy kinase-related Cdc42-binding kinase alpha.

O42844	KCC2_SCHPO	Calcium/calmodulin-dependent protein kinase type II	12135745	Cmk2, a novel serine/threonine kinase in fission yeast.

P53079	COG1_YEAST	Conserved oligomeric Golgi complex subunit 1	11703943	The Sec34/35 Golgi transport complex is related to the exocyst, defining a family of complexes involved in multiple steps of membrane traffic.

P31995	FCG2C_HUMAN	Low affinity immunoglobulin gamma Fc region receptor II-c	2531080	Human IgG Fc receptor (hFcRII; CD32) exists as multiple isoforms in macrophages, lymphocytes and IgG-transporting placental epithelium.

P77213	CAAL_ECOLI	Carboxylate-amine ligase ybdK	15211520	YbdK is a carboxylate-amine ligase with a gamma-glutamyl:cysteine ligase activity: crystal structure and enzymatic assays.

Q14210	LY6D_HUMAN	Lymphocyte antigen 6D	7790363	The human E48 antigen, highly homologous to the murine Ly-6 antigen ThB, is a GPI-anchored molecule apparently involved in keratinocyte cell-cell adhesion.

P53107	YRB30_YEAST	Ran-specific GTPase-activating protein 30	12578832	Identification and characterization of a novel RanGTP-binding protein in the yeast Saccharomyces cerevisiae.

O75943	RAD17_HUMAN	Cell cycle checkpoint protein RAD17	10884395	The human checkpoint protein hRad17 interacts with the PCNA-like proteins hRad1, hHus1, and hRad9.

O18209	PMY13_CAEEL	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase wee-1.3	16421191	The C. elegans Myt1 ortholog is required for the proper timing of oocyte maturation.

Q6L545	GID1_ORYSJ	Gibberellin receptor GID1	16193045	GIBBERELLIN INSENSITIVE DWARF1 encodes a soluble receptor for gibberellin.

P46195	KGUA_BOVIN	Guanylate kinase	7911663	Guanylate kinase from bovine retina: isolation, primary structure, and expression in E. coli.

Q15848	ADIPO_HUMAN	Adiponectin	10982546	Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway.

Q8CJ69	BMPER_MOUSE	BMP-binding endothelial regulator protein	12897139	BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiation.

P29474	NOS3_HUMAN	Nitric oxide synthase, endothelial	1378832	Cloning and expression of a cDNA encoding human endothelium-derived relaxing factor/nitric oxide synthase.

Q8MSX2	MED6_DROME	Mediator of RNA polymerase II transcription subunit 6	11259581	Drosophila Mediator complex is broadly utilized by diverse gene- specific transcription factors at different types of core promoters.

Q9ZNV8	AHP2_ARATH	Histidine-containing phosphotransfer protein 2	9804162	Characterization of genes for two-component phosphorelay mediators with a single HPt domain in Arabidopsis thaliana.

P23287	PP2B1_YEAST	Serine/threonine-protein phosphatase 2B catalytic subunit A1	1651503	Yeast has homologs (CNA1 and CNA2 gene products) of mammalian calcineurin, a calmodulin-regulated phosphoprotein phosphatase.

Q54P04	RPB7_DICDI	DNA-directed RNA polymerase II subunit rpb7	14704357	Domainal organization of the lower eukaryotic homologs of the yeast RNA polymerase II core subunit Rpb7 reflects functional conservation.

Q84Q72	HS181_ORYSJ	18.1 kDa class I heat shock protein	15803416	Characterization of the genomic structures and selective expression profiles of nine class I small heat shock protein genes clustered on two chromosomes in rice (Oryza sativa L.).

Q9NP56	PDE7B_HUMAN	cAMP-specific 3',5'-cyclic phosphodiesterase 7B	10814504	Identification of human PDE7B, a cAMP-specific phosphodiesterase.

Q86YS3	RFIP4_HUMAN	Rab11 family-interacting protein 4	12470645	Rab11-FIP4 interacts with Rab11 in a GTP-dependent manner and its overexpression condenses the Rab11 positive compartment in HeLa cells.

P68400	CSK21_HUMAN	Casein kinase II subunit alpha	2174700	Isolation and characterization of human cDNA clones encoding the alpha and the alpha' subunits of casein kinase II.

P46993	ASG7_YEAST	Protein ASG7	10568744	Identification of target sites of the alpha2-Mcm1 repressor complex in the yeast genome.

O94258	XPOT_SCHPO	Exportin-T	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9DB34	CHM2A_MOUSE	Charged multivesicular body protein 2a	15173323	Mammalian class E Vps proteins, SBP1 and mVps2/CHMP2A, interact with and regulate the function of an AAA-ATPase SKD1/Vps4B.

P49711	CTCF_HUMAN	Transcriptional repressor CTCF	9407128	The zinc finger protein CTCF binds to the APBbeta domain of the amyloid beta-protein precursor promoter. Evidence for a role in transcriptional activation.

Q8R3B1	PLCD1_MOUSE	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1	16314520	Phospholipase C-delta1 and -delta3 are essential in the trophoblast for placental development.

Q9UJZ1	STML2_HUMAN	Stomatin-like protein 2	10713127	Identification and characterization of human SLP-2, a novel homologue of stomatin (band 7.2b) present in erythrocytes and other tissues.

Q15109	RAGE_HUMAN	Advanced glycosylation end product-specific receptor	1378843	Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins.

O75398	DEAF1_HUMAN	Deformed epidermal autoregulatory factor 1 homolog	19668219	Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes.

P40562	MPH1_YEAST	ATP-dependent DNA helicase MPH1	10880470	MPH1, a yeast gene encoding a DEAH protein, plays a role in protection of the genome from spontaneous and chemically induced damage.

Q9FW44	ADR1_ARATH	Disease resistance protein ADR1	12906111	Targeted activation tagging of the Arabidopsis NBS-LRR gene, ADR1, conveys resistance to virulent pathogens.

Q8BGD7	NPAS4_MOUSE	Neuronal PAS domain-containing protein 4	14701734	Identification of a novel basic helix-loop-helix-PAS factor, NXF, reveals a Sim2 competitive, positive regulatory role in dendritic- cytoskeleton modulator drebrin gene expression.

P20152	VIME_MOUSE	Vimentin	17356066	Synemin is expressed in reactive astrocytes in neurotrauma and interacts differentially with vimentin and GFAP intermediate filament networks.

O43310	CTIF_HUMAN	CBP80/20-dependent translation initiation factor	19648179	A new MIF4G domain-containing protein, CTIF, directs nuclear cap- binding protein CBP80/20-dependent translation.

P38840	ARO9_YEAST	Aromatic amino acid aminotransferase 2	14562095	Global analysis of protein localization in budding yeast.

Q02629	NU100_YEAST	Nucleoporin NUP100/NSP100	11104765	The GLFG regions of Nup116p and Nup100p serve as binding sites for both Kap95p and Mex67p at the nuclear pore complex.

Q570C0	TIR1_ARATH	Protein TRANSPORT INHIBITOR RESPONSE 1	16627744	A plant miRNA contributes to antibacterial resistance by repressing auxin signaling.

O94810	RGS11_HUMAN	Regulator of G-protein signaling 11	9789084	A G protein gamma subunit-like domain shared between RGS11 and other RGS proteins specifies binding to Gbeta5 subunits.

Q29RQ3	DC1I1_BOVIN	Cytoplasmic dynein 1 intermediate chain 1	11967380	Subunit organization in cytoplasmic dynein subcomplexes.

P38231	FMP23_YEAST	Protein FMP23, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

O94548	YCD9_SCHPO	UPF0615 protein C1322.09	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P79065	TIP1_SCHPO	Tip elongation protein 1	15809031	Tea4p links microtubule plus ends with the formin for3p in the establishment of cell polarity.

Q09728	CUF1_SCHPO	Metal-binding regulatory protein cuf1	16467469	Copper induces cytoplasmic retention of fission yeast transcription factor cuf1.

P21825	SEC62_YEAST	Translocation protein SEC62	2000150	Assembly of yeast Sec proteins involved in translocation into the endoplasmic reticulum into a membrane-bound multisubunit complex.

Q14807	KIF22_HUMAN	Kinesin-like protein KIF22	8599929	Kid, a novel kinesin-like DNA binding protein, is localized to chromosomes and the mitotic spindle.

Q00994	BEX3_HUMAN	Protein BEX3	10764727	NADE, a p75NTR-associated cell death executor, is involved in signal transduction mediated by the common neurotrophin receptor p75NTR.

Q06697	CDC73_YEAST	Cell division control protein 73	15643076	Separation of the Saccharomyces cerevisiae Paf1 complex from RNA polymerase II results in changes in its subnuclear localization.

Q8INB9	AKT1_DROME	RAC serine/threonine-protein kinase	12893776	Control of cell number by Drosophila FOXO: downstream and feedback regulation of the insulin receptor pathway.

P0AC78	WECA_ECOLI	Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase	11700352	Conserved amino acid residues found in a predicted cytosolic domain of the lipopolysaccharide biosynthetic protein WecA are implicated in the recognition of UDP-N-acetylglucosamine.

P43033	LIS1_BOVIN	Platelet-activating factor acetylhydrolase IB subunit alpha	8028668	Miller-Dieker lissencephaly gene encodes a subunit of brain platelet- activating factor acetylhydrolase.

Q8WUM0	NU133_HUMAN	Nuclear pore complex protein Nup133	11564755	An evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cells.

Q12857	NFIA_HUMAN	Nuclear factor 1 A-type	7590749	Chromosomal localization of the four genes (NFIA, B, C, and X) for the human transcription factor nuclear factor I by FISH.

O14843	FFAR3_HUMAN	Free fatty acid receptor 3	12496283	The orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.

Q9P2M7	CING_HUMAN	Cingulin	11042084	Human and Xenopus cingulin share a modular organization of the coiled-coil rod domain: predictions for intra- and intermolecular assembly.

Q96FS4	SIPA1_HUMAN	Signal-induced proliferation-associated protein 1	9346962	Human SPA-1 product selectively expressed in lymphoid tissues is a specific GTPase-activating protein for Rap1 and Rap2.

P13010	XRCC5_HUMAN	X-ray repair cross-complementing protein 5	17396150	A novel human AP endonuclease with conserved zinc-finger-like motifs involved in DNA strand break responses.

P06340	DOA_HUMAN	HLA class II histocompatibility antigen, DO alpha chain	3000765	The human HLA class II alpha chain gene DZ alpha is distinct from genes in the DP, DQ and DR subregions.

Q05635	RNH2B_YEAST	Ribonuclease H2 subunit B	14562095	Global analysis of protein localization in budding yeast.

Q9UTN9	ATL1_SCHPO	Alkyltransferase-like protein 1	16679453	A novel DNA damage recognition protein in Schizosaccharomyces pombe.

O75477	ERLN1_HUMAN	Erlin-1	19240031	An endoplasmic reticulum (ER) membrane complex composed of SPFH1 and SPFH2 mediates the ER-associated degradation of inositol 1,4,5- trisphosphate receptors.

Q00449	MDR49_DROME	Multidrug resistance protein homolog 49	2072901	Isolation and characterization of Drosophila multidrug resistance gene homologs.

P97878	EXOC5_RAT	Exocyst complex component 5	9073068	Characterization of a cDNA encoding a subunit of the rat brain rsec6/8 complex.

Q91WW5	MRGA1_MOUSE	Mas-related G-protein coupled receptor member A1	11551509	A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons.

O13713	NAB2_SCHPO	Nuclear polyadenylated RNA-binding protein nab2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9EQZ6	RPGF4_MOUSE	Rap guanine nucleotide exchange factor 4	11056535	cAMP-GEFII is a direct target of cAMP in regulated exocytosis.

Q96RT1	LAP2_HUMAN	Protein LAP2	11375975	The hemidesmosomal protein bullous pemphigoid antigen 1 and the integrin beta 4 subunit bind to ERBIN. Molecular cloning of multiple alternative splice variants of ERBIN and analysis of their tissue expression.

P04259	K2C6B_HUMAN	Keratin, type II cytoskeletal 6B	9618173	A mutation in human keratin K6b produces a phenocopy of the K17 disorder pachyonychia congenita type 2.

Q12416	WHI5_YEAST	G1-specific transcriptional repressor WHI5	14562095	Global analysis of protein localization in budding yeast.

P51589	CP2J2_HUMAN	Cytochrome P450 2J2	8631948	Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart.

Q9FJ62	GLPQ1_ARATH	Probable glycerophosphoryl diester phosphodiesterase 1	12805588	Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis.

Q9BIS2	HSP73_DROME	Major heat shock 70 kDa protein Bb	6777045	Sequence of three copies of the gene for the major Drosophila heat shock induced protein and their flanking regions.

P27797	CALR_HUMAN	Calreticulin	8666824	Calreticulin binds hYRNA and the 52-kDa polypeptide component of the Ro/SS-A ribonucleoprotein autoantigen.

Q9WU63	HEBP2_MOUSE	Heme-binding protein 2	10640688	Discovery of a putative heme-binding protein family (SOUL/HBP) by two-tissue suppression subtractive hybridization and database searches.

P84076	HPCA_RAT	Neuron-specific calcium-binding protein hippocalcin	1280427	Molecular cloning of hippocalcin, a novel calcium-binding protein of the recoverin family exclusively expressed in hippocampus.

Q13547	HDAC1_HUMAN	Histone deacetylase 1	19049980	SKI and MEL1 cooperate to inhibit transforming growth factor-beta signal in gastric cancer cells.

P25298	RNA14_YEAST	mRNA 3'-end-processing protein RNA14	11344258	Five subunits are required for reconstitution of the cleavage and polyadenylation activities of Saccharomyces cerevisiae cleavage factor I.

Q63862	MYH11_RAT	Myosin-11	7684561	Identification of a novel smooth muscle myosin heavy chain cDNA: isoform diversity in the S1 head region.

P10912	GHR_HUMAN	Growth hormone receptor	1549776	Human growth hormone and extracellular domain of its receptor: crystal structure of the complex.

Q5YGP8	PLET1_ARATH	AP2-like ethylene-responsive transcription factor PLT1	15454085	The PLETHORA genes mediate patterning of the Arabidopsis root stem cell niche.

P31016	DLG4_RAT	Disks large homolog 4	9786987	Localization of postsynaptic density-93 to dendritic microtubules and interaction with microtubule-associated protein 1A.

Q04489	ASND1_YEAST	Asparagine synthetase domain-containing protein YML096W	14562095	Global analysis of protein localization in budding yeast.

P29147	BDH_RAT	D-beta-hydroxybutyrate dehydrogenase, mitochondrial	1567834	Primary structure of rat liver D-beta-hydroxybutyrate dehydrogenase from cDNA and protein analyses: a short-chain alcohol dehydrogenase.

Q5H8A4	PIGG_HUMAN	GPI ethanolamine phosphate transferase 2	15632136	GPI7 is the second partner of PIG-F and involved in modification of glycosylphosphatidylinositol.

P56223	PO6F1_RAT	POU domain, class 6, transcription factor 1	7901208	Brn-5 is a divergent POU domain factor highly expressed in layer IV of the neocortex.

Q8C7M3	TRIM9_MOUSE	E3 ubiquitin-protein ligase TRIM9	11331580	The tripartite motif family identifies cell compartments.

P23301	IF5A1_YEAST	Eukaryotic translation initiation factor 5A-1	19338753	eIF5A has a function in the elongation step of translation in yeast.

Q5DTL9	S4A10_MOUSE	Sodium-driven chloride bicarbonate exchanger	14592810	A SCL4A10 gene product maps selectively to the basolateral plasma membrane of choroid plexus epithelial cells.

O35412	SI1L1_RAT	Signal-induced proliferation-associated 1-like protein 1	19900557	Postsynaptic PDLIM5/Enigma homolog binds SPAR and causes dendritic spine shrinkage.

Q05086	UBE3A_HUMAN	Ubiquitin-protein ligase E3A	8988171	UBE3A/E6-AP mutations cause Angelman syndrome.

Q9VS60	SMSR1_DROME	Sphingomyelin synthase-related 1	14685263	Identification of a family of animal sphingomyelin synthases.

Q8BH60	GOPC_MOUSE	Golgi-associated PDZ and coiled-coil motif-containing protein	11520064	Identification of a PDZ domain containing Golgi protein, GOPC, as an interaction partner of frizzled.

P48363	PFD3_YEAST	Prefoldin subunit 3	9463374	A novel protein complex promoting formation of functional alpha- and gamma-tubulin.

P32354	MCM10_YEAST	Minichromosome maintenance protein 10	10783164	Mcm10 and the MCM2-7 complex interact to initiate DNA synthesis and to release replication factors from origins.

P53942	RNH2A_YEAST	Ribonuclease H2 subunit A	14734815	RNase H2 of Saccharomyces cerevisiae is a complex of three proteins.

P32082	GHRHR_MOUSE	Growth hormone-releasing hormone receptor	1334535	Pit-1-dependent expression of the receptor for growth hormone releasing factor mediates pituitary cell growth.

Q91V79	FITM1_MOUSE	Fat storage-inducing transmembrane protein 1	18160536	Evolutionarily conserved gene family important for fat storage.

P23470	PTPRG_HUMAN	Receptor-type tyrosine-protein phosphatase gamma	8382771	Identification of a carbonic anhydrase-like domain in the extracellular region of RPTP gamma defines a new subfamily of receptor tyrosine phosphatases.

Q71A39	PHLP1_DICDI	Phosducin-like protein 1	14517243	Phosducin-like proteins in Dictyostelium discoideum: implications for the phosducin family of proteins.

P50226	ST1A2_HUMAN	Sulfotransferase 1A2	9119390	Cloning, structural organization, and chromosomal mapping of the human phenol sulfotransferase STP2 gene.

Q96LB8	PGRP4_HUMAN	Peptidoglycan recognition protein 4	11461926	Peptidoglycan recognition proteins: a novel family of four human innate immunity pattern recognition molecules.

P31947	1433S_HUMAN	14-3-3 protein sigma	19172738	Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein.

Q12366	NDJ1_YEAST	Non-disjunction protein 1	9157883	Ndj1p, a meiotic telomere protein required for normal chromosome synapsis and segregation in yeast.

P30176	YBIA_ECOLI	Swarming motility protein ybiA	17122336	Genome-wide screening of genes required for swarming motility in Escherichia coli K-12.

P29350	PTN6_HUMAN	Tyrosine-protein phosphatase non-receptor type 6	7781604	Tyrosine phosphorylation of an SH2-containing protein tyrosine phosphatase is coupled to platelet thrombin receptor via a pertussis toxin-sensitive heterotrimeric G-protein.

Q12039	HMI1_YEAST	ATP-dependent DNA helicase HMI1, mitochondrial	10409639	The DNA helicase, Hmi1p, is transported into mitochondria by a C- terminal cleavable targeting signal.

Q9UKJ1	PILRA_HUMAN	Paired immunoglobulin-like type 2 receptor alpha	10660620	PILRalpha, a novel immunoreceptor tyrosine-based inhibitory motif- bearing protein, recruits SHP-1 upon tyrosine phosphorylation and is paired with the truncated counterpart PILRbeta.

Q9UMS0	NFU1_HUMAN	NFU1 iron-sulfur cluster scaffold homolog, mitochondrial	11342215	Identification of human and mouse HIRA-interacting protein-5 (HIRIP5), two mammalian representatives in a family of phylogenetically conserved proteins with a role in the biogenesis of Fe/S proteins.

Q9URW9	YLX7_SCHPO	Putative aldehyde dehydrogenase-like protein C922.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q92565	RPGF5_HUMAN	Rap guanine nucleotide exchange factor 5	10486569	Characterization of GFR, a novel guanine nucleotide exchange factor for Rap1.

Q9Y6M0	TEST_HUMAN	Testisin	9826525	Cloning and tissue distribution of a novel serine protease esp-1 from human eosinophils.

P25847	MSH2_YEAST	DNA mismatch repair protein MSH2	10523644	Separation-of-function mutations in Saccharomyces cerevisiae MSH2 that confer mismatch repair defects but do not affect nonhomologous- tail removal during recombination.

O60177	YG42_SCHPO	Uncharacterized ATP-dependent helicase C23E6.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P51865	TDGF1_MOUSE	Teratocarcinoma-derived growth factor	10640699	Membrane-anchorage of Cripto protein by glycosylphosphatidylinositol and its distribution during early mouse development.

O35048	3BHS7_RAT	3 beta-hydroxysteroid dehydrogenase type 7	9199244	Isolation of a novel cDNA whose corresponding mRNA is accumulated in growth-arrested confluent but not in growing sub-confluent rat 3Y1 cells.

P77432	LSRK_ECOLI	Autoinducer 2 kinase lsrK	15601708	Regulation of uptake and processing of the quorum-sensing autoinducer AI-2 in Escherichia coli.

P20849	CO9A1_HUMAN	Collagen alpha-1(IX) chain	9707347	Human COL9A1 and COL9A2 genes. Two genes of 90 and 15 kb code for similar polypeptides of the same collagen molecule.

Q80W88	HOMEZ_MOUSE	Homeobox and leucine zipper protein Homez	12925734	Homez, a homeobox leucine zipper gene specific to the vertebrate lineage.

Q9P376	FCP1_SCHPO	RNA polymerase II subunit A C-terminal domain phosphatase	11934898	Characterization of the CTD phosphatase Fcp1 from fission yeast. Preferential dephosphorylation of serine 2 versus serine 5.

Q92823	NRCAM_HUMAN	Neuronal cell adhesion molecule	8812479	Characterization of a highly conserved human homolog to the chicken neural cell surface protein Bravo/Nr-CAM that maps to chromosome band 7q31.

Q12417	PRP46_YEAST	Pre-mRNA-splicing factor PRP46	12554883	Identification and characterization of Prp45p and Prp46p, essential pre-mRNA splicing factors.

Q80Z34	NP311_RAT	Neuronal protein 3.1	15485502	P311 accelerates nerve regeneration of the axotomized facial nerve.

P32573	SPS19_YEAST	Peroxisomal 2,4-dienoyl-CoA reductase SPS19	9268358	The Saccharomyces cerevisiae peroxisomal 2,4-dienoyl-CoA reductase is encoded by the oleate-inducible gene SPS19.

Q66KI8	APCD1_XENLA	Protein APCDD1	20393562	APCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplex.

P36163	OMA1_YEAST	Mitochondrial metalloendopeptidase OMA1	12963738	Oma1, a novel membrane-bound metallopeptidase in mitochondria with activities overlapping with the m-AAA protease.

Q01098	NMDE3_MOUSE	Glutamate [NMDA] receptor subunit epsilon-3	1377365	Molecular diversity of the NMDA receptor channel.

Q02747	GUC2A_HUMAN	Guanylin	8095028	The circulating bioactive form of human guanylin is a high molecular weight peptide (10.3 kDa).

Q07471	THI3_YEAST	Thiamine metabolism regulatory protein THI3	14562095	Global analysis of protein localization in budding yeast.

P45695	COF1A_XENLA	Cofilin-1-A	8603919	Xenopus laevis actin-depolymerizing factor/cofilin: a phosphorylation-regulated protein essential for development.

O60610	DIAP1_HUMAN	Protein diaphanous homolog 1	9360932	Nonsyndromic deafness DFNA1 associated with mutation of a human homolog of the Drosophila gene diaphanous.

P62805	H4_HUMAN	Histone H4	3035717	Protein-DNA interactions in vivo upstream of a cell cycle-regulated human H4 histone gene.

Q9I9K7	TBX20_DANRE	T-box transcription factor TBX20	10906473	tbx20, a new vertebrate T-box gene expressed in the cranial motor neurons and developing cardiovascular structures in zebrafish.

P21741	MK_HUMAN	Midkine	1639750	Genomic structure of human midkine (MK), a retinoic acid-responsive growth/differentiation factor.

Q14137	BOP1_HUMAN	Ribosome biogenesis protein BOP1	16043514	Mammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferation.

Q9FNA2	PAO1_ARATH	Polyamine oxidase 1	16778015	Heterologous expression and biochemical characterization of a polyamine oxidase from Arabidopsis involved in polyamine back conversion.

O14048	UBX2_SCHPO	UBX domain-containing protein 2	15120077	The Ubx2 and Ubx3 cofactors direct Cdc48 activity to proteolytic and nonproteolytic ubiquitin-dependent processes.

P46821	MAP1B_HUMAN	Microtubule-associated protein 1B	12147674	Microtubule-associated protein 1B: a neuronal binding partner for gigaxonin.

Q949T8	ASHR3_ARATH	Histone-lysine N-methyltransferase ASHR3	17978851	The Arabidopsis SET-domain protein ASHR3 is involved in stamen development and interacts with the bHLH transcription factor ABORTED MICROSPORES (AMS).

Q6SJP8	FG17_DANRE	Fibroblast growth factor 17	15196956	fgf17b, a novel member of Fgf family, helps patterning zebrafish embryos.

Q9XIJ5	PUB18_ARATH	U-box domain-containing protein 18	14657406	A large complement of the predicted Arabidopsis ARM repeat proteins are members of the U-box E3 ubiquitin ligase family.

Q9WVL4	RK_MOUSE	Rhodopsin kinase	10097103	Abnormal photoresponses and light-induced apoptosis in rods lacking rhodopsin kinase.

Q9LNV3	STP2_ARATH	Sugar transport protein 2	10074716	A male gametophyte-specific monosaccharide transporter in Arabidopsis.

P16989	DBPA_HUMAN	DNA-binding protein A	7628487	Characterization of the gene for dbpA, a family member of the nucleic-acid-binding proteins containing a cold-shock domain.

Q9JII1	INP5E_MOUSE	72 kDa inositol polyphosphate 5-phosphatase	19668215	INPP5E mutations cause primary cilium signaling defects, ciliary instability and ciliopathies in human and mouse.

P83009	PLMS_LAMNA	Phospholemman-like protein	11676495	N-terminal sequences of small ion channels in rectal glands of sharks: a biochemical hallmark for classification and phylogeny?

P12524	MYCL1_HUMAN	Protein L-Myc-1	3322939	The human myc gene family: structure and activity of L-myc and an L- myc pseudogene.

P42939	MVB12_YEAST	Multivesicular body sorting factor 12	17442384	Molecular architecture and functional model of the complete yeast ESCRT-I heterotetramer.

O88531	PPT1_MOUSE	Palmitoyl-protein thioesterase 1	9685319	Mouse palmitoyl protein thioesterase: gene structure and expression of cDNA.

O02482	UNC37_CAEEL	Transcription factor unc-37	9165118	The Groucho-like transcription factor UNC-37 functions with the neural specificity gene unc-4 to govern motor neuron identity in C. elegans.

P58950	GR10A_DROME	Gustatory receptor 10a	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

O60942	MCE1_HUMAN	mRNA-capping enzyme	9512541	Isolation and characterization of a human cDNA for mRNA 5'-capping enzyme.

Q9NPB6	PAR6A_HUMAN	Partitioning defective 6 homolog alpha	15590654	Structure of a cell polarity regulator, a complex between atypical PKC and Par6 PB1 domains.

P38063	KPR4_YEAST	Ribose-phosphate pyrophosphokinase 4	10212224	Genetic analysis and enzyme activity suggest the existence of more than one minimal functional unit capable of synthesizing phosphoribosyl pyrophosphate in Saccharomyces cerevisiae.

Q06053	DUS3_YEAST	tRNA-dihydrouridine synthase 3	14970222	The specificities of four yeast dihydrouridine synthases for cytoplasmic tRNAs.

Q8K4S7	CBLB_RAT	E3 ubiquitin-protein ligase CBL-B	12118252	Cblb is a major susceptibility gene for rat type 1 diabetes mellitus.

O75324	SNN_HUMAN	Stannin	9657854	Chromosomal localization and characterization of the stannin (Snn) gene.

P42124	EZ_DROME	Histone-lysine N-methyltransferase E(z)	12771214	The Drosophila Corto protein interacts with Polycomb-group proteins and the GAGA factor.

Q9VT53	INSL4_DROME	Probable insulin-like peptide 4	11250149	An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control.

P54824	DDX6_XENLA	ATP-dependent RNA helicase ddx6	9023105	Xp54, the Xenopus homologue of human RNA helicase p54, is an integral component of stored mRNP particles in oocytes.

P12081	SYHC_HUMAN	Histidyl-tRNA synthetase, cytoplasmic	1549469	Human histidyl-tRNA synthetase: recognition of amino acid signature regions in class 2a aminoacyl-tRNA synthetases.

P41182	BCL6_HUMAN	B-cell lymphoma 6 protein	12590135	The histone deacetylase 9 gene encodes multiple protein isoforms.

P40581	GPX3_YEAST	Peroxiredoxin HYR1	12743123	Ybp1 is required for the hydrogen peroxide-induced oxidation of the Yap1 transcription factor.

O97143	PLK4_DROME	Serine/threonine-protein kinase PLK4	16326102	SAK/PLK4 is required for centriole duplication and flagella development.

P62745	RHOB_HUMAN	Rho-related GTP-binding protein RhoB	1400319	Post-translational modifications of p21rho proteins.

P35222	CTNB1_HUMAN	Catenin beta-1	11751639	Chromatin-specific regulation of LEF-1-beta-catenin transcription activation and inhibition in vitro.

Q08949	DDC1_YEAST	DNA damage checkpoint protein 1	9311982	The novel DNA damage checkpoint protein ddc1p is phosphorylated periodically during the cell cycle and in response to DNA damage in budding yeast.

P12019	PDE1_DICDI	cAMP/cGMP-dependent 3',5'-cAMP/cGMP phosphodiesterase A	17040207	Seven Dictyostelium discoideum phosphodiesterases degrade three pools of cAMP and cGMP.

P53292	RT35_YEAST	37S ribosomal protein S35, mitochondrial	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Q14674	ESPL1_HUMAN	Separin	12194817	Regulation of human separase by securin binding and autocleavage.

Q10P60	HS26P_ORYSJ	26.7 kDa heat shock protein, chloroplastic	19703271	Rice sHsp genes: genomic organization and expression profiling under stress and development.

Q9LNR3	LOX3_ARATH	Lipoxygenase 3, chloroplastic	18216250	Mapping methyl jasmonate-mediated transcriptional reprogramming of metabolism and cell cycle progression in cultured Arabidopsis cells.

P43688	NKX26_MOUSE	Homeobox protein Nkx-2.6	11390666	Nkx2.5 and Nkx2.6, homologs of Drosophila tinman, are required for development of the pharynx.

O46635	5HT2A_CANFA	5-hydroxytryptamine receptor 2A	15862800	Molecular and pharmacological characterization of serotonin 5-HT(2A) and 5-HT(2B) receptor subtypes in dog.

P49893	WN11B_XENLA	Protein Wnt-11b	8306880	Xwnt-11: a maternally expressed Xenopus wnt gene.

O60359	CCG3_HUMAN	Voltage-dependent calcium channel gamma-3 subunit	10221464	Identification and cloning of putative human neuronal voltage-gated calcium channel gamma-2 and gamma-3 subunits: neurologic implications.

Q9D906	ATG7_MOUSE	Ubiquitin-like modifier-activating enzyme ATG7	11890701	Murine Apg12p has a substrate preference for murine Apg7p over three Apg8p homologs.

P52564	MP2K6_HUMAN	Dual specificity mitogen-activated protein kinase kinase 6	8621675	Characterization of the structure and function of a novel MAP kinase kinase (MKK6).

Q9S7R4	PP125_ARATH	Pentatricopeptide repeat-containing protein At1g74900, mitochondrial	17965268	The pentatricopeptide repeat gene OTP43 is required for trans- splicing of the mitochondrial nad1 intron 1 in Arabidopsis thaliana.

O44081	DKC1_DROME	H/ACA ribonucleoprotein complex subunit 4	12645924	Mutations in Nop60B, the Drosophila homolog of human dyskeratosis congenita 1, affect the maintenance of the germ-line stem cell lineage during spermatogenesis.

Q6PDZ2	TAF1C_MOUSE	TATA box-binding protein-associated factor RNA polymerase I subunit C	9050847	Cloning of murine RNA polymerase I-specific TAF factors: conserved interactions between the subunits of the species-specific transcription initiation factor TIF-IB/SL1.

Q7KNS3	LIS1_DROME	Lissencephaly-1 homolog	10559989	Drosophila Lissencephaly-1 functions with Bic-D and dynein in oocyte determination and nuclear positioning.

O13757	YF27_SCHPO	Meiotic chromosome segregation protein C17A2.07c	16169489	Novel genes required for meiotic chromosome segregation are identified by a high-throughput knockout screen in fission yeast.

O94766	B3GA3_HUMAN	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3	10842173	Structure/function of the human Ga1beta1,3-glucuronosyltransferase. Dimerization and functional activity are mediated by two crucial cysteine residues.

Q9P2J3	KLHL9_HUMAN	Kelch-like protein 9	19995937	The Cul3-KLHL21 E3 ubiquitin ligase targets aurora B to midzone microtubules in anaphase and is required for cytokinesis.

Q9M077	AUR1_ARATH	Serine/threonine-protein kinase Aurora-1	15469496	Molecular dissection of plant cytokinesis and phragmoplast structure: a survey of GFP-tagged proteins.

Q8L4R0	TGD1_ARATH	Protein TRIGALACTOSYLDIACYLGLYCEROL 1, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

O94570	AATR2_SCHPO	Aromatic amino acid aminotransferase C1773.13	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P52298	NCBP2_HUMAN	Nuclear cap-binding protein subunit 2	8601613	A nuclear cap-binding complex binds Balbiani ring pre-mRNA cotranscriptionally and accompanies the ribonucleoprotein particle during nuclear export.

O74381	POF9_SCHPO	F-box protein pof9	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q62226	SHH_MOUSE	Sonic hedgehog protein	15075292	Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and long-range signaling in vertebrates.

Q03445	GLK1_DROME	Glutamate receptor 1	1359540	Glutamate receptors of Drosophila melanogaster: cloning of a kainate- selective subunit expressed in the central nervous system.

P07098	LIPG_HUMAN	Gastric triacylglycerol lipase	2753032	Human gastric lipase. The N-terminal tetrapeptide is essential for lipid binding and lipase activity.

Q23997	CH47_DROME	Chitinase-like protein DS47	7875581	An abundantly secreted glycoprotein from Drosophila melanogaster is related to mammalian secretory proteins produced in rheumatoid tissues and by activated macrophages.

Q12517	DCP1_YEAST	mRNA-decapping enzyme subunit 1	11780629	The DEAD box helicase, Dhh1p, functions in mRNA decapping and interacts with both the decapping and deadenylase complexes.

P49095	GCSP_YEAST	Glycine dehydrogenase [decarboxylating], mitochondrial	8830251	Specific induction by glycine of the gene for the P-subunit of glycine decarboxylase from Saccharomyces cerevisiae.

Q49SH1	NCKX5_DANRE	Sodium/potassium/calcium exchanger 5	16357253	SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans.

P63036	DNJA1_RAT	DnaJ homolog subfamily A member 1	9605323	Isolation and characterization of a DnaJ-like protein in rats: the C- terminal 10-kDa domain of hsc70 is not essential for stimulating the ATP-hydrolytic activity of hsc70 by a DnaJ-like protein.

P84830	SKSP5_ASCTR	Skin secreted peptide 5	15922344	Bradykinin-related peptides and tryptophyllins in the skin secretions of the most primitive extant frog, Ascaphus truei.

O54888	RPA2_RAT	DNA-directed RNA polymerase I subunit RPA2	9422795	Affinity purification of mammalian RNA polymerase I. Identification of an associated kinase.

Q8VY26	CCD8_ARATH	Carotenoid cleavage dioxygenase 8, chloroplastic	16507088	Characterization of three members of the Arabidopsis carotenoid cleavage dioxygenase family demonstrates the divergent roles of this multifunctional enzyme family.

Q9EPQ2	RPGR1_MOUSE	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1	12651948	The retinitis pigmentosa GTPase regulator (RPGR)-interacting protein: subserving RPGR function and participating in disk morphogenesis.

P07093	GDN_HUMAN	Glia-derived nexin	2877744	A glia-derived neurite promoting factor with protease inhibitory activity belongs to the protease nexins.

Q9LZJ6	ATL5_ARATH	RING-H2 finger protein ATL5	10480382	Early elicitor induction in members of a novel multigene family coding for highly related RING-H2 proteins in Arabidopsis thaliana.

P80317	TCPZ_MOUSE	T-complex protein 1 subunit zeta	7953530	Identification of six Tcp-1-related genes encoding divergent subunits of the TCP-1-containing chaperonin.

Q9JIS5	SV2A_MOUSE	Synaptic vesicle glycoprotein 2A	12687700	Differential distribution and developmental expression of synaptic vesicle protein 2 isoforms in the mouse retina.

P02829	HSP82_YEAST	ATP-dependent molecular chaperone HSP82	2674684	hsp82 is an essential protein that is required in higher concentrations for growth of cells at higher temperatures.

P18851	GBB_YEAST	Guanine nucleotide-binding protein subunit beta	10749875	Functional analysis of Plp1 and Plp2, two homologues of phosducin in yeast.

P38090	AGP2_YEAST	General amino acid permease AGP2	10545096	Molecular characterization of carnitine-dependent transport of acetyl-CoA from peroxisomes to mitochondria in Saccharomyces cerevisiae and identification of a plasma membrane carnitine transporter, Agp2p.

Q9V460	SPT5H_DROME	Transcription elongation factor SPT5	12782658	NELF and DSIF cause promoter proximal pausing on the hsp70 promoter in Drosophila.

Q3UYV9	NCBP1_MOUSE	Nuclear cap-binding protein subunit 1	19632182	Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation.

Q09142	ORC2_SCHPO	Origin recognition complex subunit 2	11850415	Purification and characterization of the Schizosaccharomyces pombe origin recognition complex: interaction with origin DNA and Cdc18 protein.

O94925	GLSK_HUMAN	Glutaminase kidney isoform, mitochondrial	11015561	Cloning and analysis of unique human glutaminase isoforms generated by tissue-specific alternative splicing.

Q6R5N8	TLR13_MOUSE	Toll-like receptor 13	17452530	The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling.

Q9PTX2	CIRBP_RANCA	Cold-inducible RNA-binding protein	10817911	Cloning and characterization of amphibian cold inducible RNA-binding protein.

Q96S55	WRIP1_HUMAN	ATPase WRNIP1	15670210	Human Werner helicase interacting protein 1 (WRNIP1) functions as a novel modulator for DNA polymerase delta.

P29460	IL12B_HUMAN	Interleukin-12 subunit beta	1674604	Coexpression of two distinct genes is required to generate secreted bioactive cytotoxic lymphocyte maturation factor.

P38844	DSE2_YEAST	Protein DSE2	11309124	Overlapping and distinct roles of the duplicated yeast transcription factors Ace2p and Swi5p.

Q9P0M9	RM27_HUMAN	39S ribosomal protein L27, mitochondrial	11279069	Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria.

P35233	PTN2_RAT	Tyrosine-protein phosphatase non-receptor type 2	1849097	Molecular cloning and expression of a protein-tyrosine phosphatase showing homology with transcription factors Fos and Jun.

Q9DBL2	GDAP2_MOUSE	Ganglioside-induced differentiation-associated protein 2	10217254	Isolation of 10 differentially expressed cDNAs in differentiated Neuro2a cells induced through controlled expression of the GD3 synthase gene.

Q8LAD2	SUCA2_ARATH	Succinyl-CoA ligase [GDP-forming] subunit alpha-2, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P79255	IL8_BOVIN	Interleukin-8	8737490	Molecular cloning and expression of bovine interleukin-8.

Q9UMR5	PPT2_HUMAN	Lysosomal thioesterase PPT2	9341199	Molecular cloning and expression of palmitoyl-protein thioesterase 2 (PPT2), a homolog of lysosomal palmitoyl-protein thioesterase with a distinct substrate specificity.

Q9UTN0	YII3_SCHPO	Uncharacterized transcriptional regulatory protein C139.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9ZR12	GRH1_ARATH	GRR1-like protein 1	15917797	The F-box protein TIR1 is an auxin receptor.

Q9BZC1	CELF4_HUMAN	CUGBP Elav-like family member 4	10893231	A family of human RNA-binding proteins related to the Drosophila Bruno translational regulator.

Q9NQC7	CYLD_HUMAN	Ubiquitin carboxyl-terminal hydrolase CYLD	18313383	The structure of the CYLD USP domain explains its specificity for Lys63-linked polyubiquitin and reveals a B box module.

Q86P48	ATBP_DROME	AT-rich binding protein	11841500	Identification and characterization of a Drosophila homologue of ATBP.

Q6E2N3	TRI33_DANRE	E3 ubiquitin-protein ligase TRIM33	15314655	The zebrafish moonshine gene encodes transcriptional intermediary factor 1 gamma, an essential regulator of hematopoiesis.

Q8W4D8	DDL_ARATH	FHA domain-containing protein DDL	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

Q02975	Z354A_RAT	Zinc finger protein 354A	8382778	Kid-1, a putative renal transcription factor: regulation during ontogeny and in response to ischemia and toxic injury.

Q60760	GRB10_MOUSE	Growth factor receptor-bound protein 10	15722337	Phosphorylation of grb10 regulates its interaction with 14-3-3.

P51156	RAB26_RAT	Ras-related protein Rab-26	7864900	Molecular cloning of a new member of the Rab protein family, Rab 26, from rat pancreas.

Q54Z26	GLYC1_DICDI	Serine hydroxymethyltransferase 1	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q9Y561	LRP12_HUMAN	Low-density lipoprotein receptor-related protein 12	12809483	ST7 is a novel low-density lipoprotein receptor-related protein (LRP) with a cytoplasmic tail that interacts with proteins related to signal transduction pathways.

Q9Z0G8	WIPF3_RAT	WAS/WASL-interacting protein family member 3	8906616	CR16, a novel proline-rich protein expressed in rat brain neurons, binds to SH3 domains and is a MAP kinase substrate.

P25451	PSB3_YEAST	Proteasome component PUP3	9087403	Structure of 20S proteasome from yeast at 2.4-A resolution.

P10867	GGLO_RAT	L-gulonolactone oxidase	3338984	Isolation and sequence analysis of a complementary DNA encoding rat liver L-gulono-gamma-lactone oxidase, a key enzyme for L-ascorbic acid biosynthesis.

P23897	GUC2C_RAT	Heat-stable enterotoxin receptor	1701694	Guanylyl cyclase is a heat-stable enterotoxin receptor.

Q6AYJ4	REC8_RAT	Meiotic recombination protein REC8 homolog	12615909	Meiotic cohesin REC8 marks the axial elements of rat synaptonemal complexes before cohesins SMC1beta and SMC3.

Q76L34	PCYAA_ASTLO	Photoactivated adenylate cyclase subunit alpha	14630964	Photoactivated adenylyl cyclase controls phototaxis in the flagellate Euglena gracilis.

Q06892	POS5_YEAST	NADH kinase POS5, mitochondrial	12727869	A novel NADH kinase is the mitochondrial source of NADPH in Saccharomyces cerevisiae.

Q07794	RT109_YEAST	Histone acetyltransferase RTT109	15282802	Localization of proteins that are coordinately expressed with Cln2 during the cell cycle.

Q61088	FZD4_MOUSE	Frizzled-4	15035989	Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair.

Q9ERA6	TFP11_MOUSE	Tuftelin-interacting protein 11	10806191	A tuftelin-interacting protein (TIP39) localizes to the apical secretory pole of mouse ameloblasts.

Q63186	EI2BD_RAT	Translation initiation factor eIF-2B subunit delta	8929216	eIF2B, the guanine nucleotide-exchange factor for eukaryotic initiation factor 2. Sequence conservation between the alpha, beta and delta subunits of eIF2B from mammals and yeast.

P24623	CRYAA_RAT	Alpha-crystallin A chain	1429679	Alpha A-crystallin is expressed in non-ocular tissues.

Q14114	LRP8_HUMAN	Low-density lipoprotein receptor-related protein 8	8626535	Human apolipoprotein E receptor 2. A novel lipoprotein receptor of the low density lipoprotein receptor family predominantly expressed in brain.

O59706	SAP61_SCHPO	CWF complex protein sap61	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P38398	BRCA1_HUMAN	Breast cancer type 1 susceptibility protein	9528852	BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression.

Q9UHD8	SEPT9_HUMAN	Septin-9	16007136	Possible role of Rho/Rhotekin signaling in mammalian septin organization.

Q9QZR5	HIPK2_MOUSE	Homeodomain-interacting protein kinase 2	15526030	Axin stimulates p53 functions by activation of HIPK2 kinase through multimeric complex formation.

Q550U9	PLBLA_DICDI	Phospholipase B-like protein A	15193148	Identification of phospholipase B from Dictyostelium discoideum reveals a new lipase family present in mammals, flies and nematodes, but not yeast.

O95391	SLU7_HUMAN	Pre-mRNA-splicing factor SLU7	15728250	Stress alters the subcellular distribution of hSlu7 and thus modulates alternative splicing.

P63081	VATL_RAT	V-type proton ATPase 16 kDa proteolipid subunit	1400263	Molecular cloning of a rat liver cDNA encoding the 16 kDa subunit of vacuolar H(+)-ATPases: organellar and tissue distribution of 16 kDa proteolipids.

Q12271	INP53_YEAST	Inositol-1,4,5-trisphosphate 5-phosphatase 3	11094088	The yeast inositol polyphosphate 5-phosphatases inp52p and inp53p translocate to actin patches following hyperosmotic stress: mechanism for regulating phosphatidylinositol 4,5-bisphosphate at plasma membrane invaginations.

P51116	FXR2_HUMAN	Fragile X mental retardation syndrome-related protein 2	7489725	The fragile X mental retardation syndrome protein interacts with novel homologs FXR1 and FXR2.

Q6EVK6	BRM_ARATH	ATP-dependent helicase BRM	18508955	The Arabidopsis BRAHMA chromatin-remodeling ATPase is involved in repression of seed maturation genes in leaves.

P0CD99	MPH2_YEAST	Alpha-glucosides permease MPH2	12210897	Characterization of the putative maltose transporters encoded by YDL247w and YJR160c.

Q9JJN5	CBPN_MOUSE	Carboxypeptidase N catalytic chain	10878383	Pro-carboxypeptidase R is an acute phase protein in the mouse, whereas carboxypeptidase N is not.

P22897	MRC1_HUMAN	Macrophage mannose receptor 1	2373685	Primary structure of the mannose receptor contains multiple motifs resembling carbohydrate-recognition domains.

P12961	7B2_MOUSE	Neuroendocrine protein 7B2	10089884	The neuroendocrine protein 7B2 is required for peptide hormone processing in vivo and provides a novel mechanism for pituitary Cushing's disease.

O48963	PHOT1_ARATH	Phototropin-1	10542152	Arabidopsis NPH3: a NPH1 photoreceptor-interacting protein essential for phototropism.

Q5PNU3	AMSH3_ARATH	AMSH-like ubiquitin thiolesterase 3	20543027	The deubiquitinating enzyme AMSH3 is required for intracellular trafficking and vacuole biogenesis in Arabidopsis thaliana.

P0ADA1	TESA_ECOLI	Acyl-CoA thioesterase I	8432696	Molecular cloning, sequencing, and mapping of the gene encoding protease I and characterization of proteinase and proteinase-defective Escherichia coli mutants.

Q10656	EGL15_CAEEL	Myoblast growth factor receptor egl-15	11689700	The Caenorhabditis elegans EGL-15 signaling pathway implicates a DOS- like multisubstrate adaptor protein in fibroblast growth factor signal transduction.

Q13501	SQSTM_HUMAN	Sequestosome-1	8702753	p62, a phosphotyrosine-independent ligand of the SH2 domain of p56lck, belongs to a new class of ubiquitin-binding proteins.

P34078	LTV1_YEAST	Protein LTV1	16888326	Ltv1 is required for efficient nuclear export of the ribosomal small subunit in Saccharomyces cerevisiae.

Q04900	MUC24_HUMAN	Sialomucin core protein 24	11027692	Relationship between novel isoforms, functionally important domains, and subcellular distribution of CD164/endolyn.

P39447	ZO1_MOUSE	Tight junction protein ZO-1	16188940	Bves modulates epithelial integrity through an interaction at the tight junction.

P47977	CTH2_YEAST	mRNA decay factor CTH2	15652485	Coordinated remodeling of cellular metabolism during iron deficiency through targeted mRNA degradation.

C0LGL9	FEI2_ARATH	LRR receptor-like serine/threonine-protein kinase FEI 2	19017745	Two leucine-rich repeat receptor kinases mediate signaling, linking cell wall biosynthesis and ACC synthase in Arabidopsis.

P32562	CDC5_YEAST	Cell cycle serine/threonine-protein kinase CDC5/MSD2	8321244	A multicopy suppressor gene of the Saccharomyces cerevisiae G1 cell cycle mutant gene dbf4 encodes a protein kinase and is identified as CDC5.

P51784	UBP11_HUMAN	Ubiquitin carboxyl-terminal hydrolase 11	18408009	USP11 stabilizes HPV-16E7 and further modulates the E7 biological activity.

Q16667	CDKN3_HUMAN	Cyclin-dependent kinase inhibitor 3	10669749	Overexpression of kinase-associated phosphatase (KAP) in breast and prostate cancer and inhibition of the transformed phenotype by antisense KAP expression.

O13870	NOT3_SCHPO	General negative regulator of transcription subunit 3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8N6P7	I22R1_HUMAN	Interleukin-22 receptor subunit alpha-1	10875937	Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R.

Q9P2E9	RRBP1_HUMAN	Ribosome-binding protein 1	9628588	Identification of multiple forms of 180-kDa ribosome receptor in human cells.

P47942	DPYL2_RAT	Dihydropyrimidinase-related protein 2	9375656	Brain CRMP forms heterotetramers similar to liver dihydropyrimidinase.

P47946	TRK1_SCHPO	Potassium transport protein 1	7642145	Isolation and characterization of SpTRK, a gene from Schizosaccharomyces pombe predicted to encode a K+ transporter protein.

Q96KS0	EGLN2_HUMAN	Egl nine homolog 2	11850811	Novel estrogen and tamoxifen induced genes identified by SAGE (Serial Analysis of Gene Expression).

Q8NKC1	COMT2_SCHPO	Probable catechol O-methyltransferase 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O14323	MCP4_SCHPO	Meiotic coiled-coil protein 4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8NFD5	ARI1B_HUMAN	AT-rich interactive domain-containing protein 1B	15170388	Two related ARID family proteins are alternative subunits of human SWI/SNF complexes.

O94513	EIF3E_SCHPO	Eukaryotic translation initiation factor 3 subunit E	12553909	Schizosaccharomyces pombe Int6 and Ras homologs regulate cell division and mitotic fidelity via the proteasome.

O35280	CHK1_MOUSE	Serine/threonine-protein kinase Chk1	10859164	Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint.

Q13164	MK07_HUMAN	Mitogen-activated protein kinase 7	7759517	Components of a new human protein kinase signal transduction pathway.

Q23490	MLT7_CAEEL	Peroxidase mlt-7	19406744	Combined extracellular matrix cross-linking activity of the peroxidase MLT-7 and the dual oxidase BLI-3 is critical for post- embryonic viability in Caenorhabditis elegans.

O15273	TELT_HUMAN	Telethonin	10984498	FATZ, a filamin-, actinin-, and telethonin-binding protein of the Z- disc of skeletal muscle.

Q3E7A6	YM007_YEAST	Uncharacterized protein YML007C-A, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

Q9NNW5	WDR6_HUMAN	WD repeat-containing protein 6	17216128	Association of LKB1 with a WD-repeat protein WDR6 is implicated in cell growth arrest and p27(Kip1) induction.

P53072	TAN1_YEAST	tRNA acetyltransferase TAN1	15037780	The Saccharomyces cerevisiae TAN1 gene is required for N4- acetylcytidine formation in tRNA.

O14795	UN13B_HUMAN	Protein unc-13 homolog B	10233166	Human munc13 is a diacylglycerol receptor that induces apoptosis and may contribute to renal cell injury in hyperglycemia.

Q06810	OPY2_YEAST	Protein OPY2	16543225	Adaptor protein Ste50p links the Ste11p MEKK to the HOG pathway through plasma membrane association.

P40236	HHP2_SCHPO	Casein kinase I homolog hhp2	8026462	Characterization of two protein kinases from Schizosaccharomyces pombe involved in the regulation of DNA repair.

P15567	PUR6_SCHPO	Phosphoribosylaminoimidazole carboxylase	3221399	DNA sequence analysis of the ade6 gene of Schizosaccharomyces pombe. Wild-type and mutant alleles including the recombination host spot allele ade6-M26.

Q13901	C1D_HUMAN	Nuclear nucleic acid-binding protein C1D	9469821	cDNA cloning, recombinant expression and characterization of polypetides with exceptional DNA affinity.

Q61060	FOXD3_MOUSE	Forkhead box protein D3	12381664	Requirement for Foxd3 in maintaining pluripotent cells of the early mouse embryo.

Q99N50	SYTL2_MOUSE	Synaptotagmin-like protein 2	11773082	The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain.

Q9UPN4	AZI1_HUMAN	5-azacytidine-induced protein 1	14654843	Proteomic characterization of the human centrosome by protein correlation profiling.

P53080	EDC1_YEAST	Enhancer of mRNA-decapping protein 1	11139489	Two related proteins, Edc1p and Edc2p, stimulate mRNA decapping in Saccharomyces cerevisiae.

P84833	TY3_ASCTR	Tryptophyllin-3	15922344	Bradykinin-related peptides and tryptophyllins in the skin secretions of the most primitive extant frog, Ascaphus truei.

P02458	CO2A1_HUMAN	Collagen alpha-1(II) chain	1429602	An amino acid substitution (Gly853-->Glu) in the collagen alpha 1(II) chain produces hypochondrogenesis.

Q15631	TSN_HUMAN	Translin	7663511	A novel gene, Translin, encodes a recombination hotspot binding protein associated with chromosomal translocations.

Q9NS84	CHST7_HUMAN	Carbohydrate sulfotransferase 7	10913333	Diversity of N-acetylglucosamine-6-O-sulfotransferases: molecular cloning of a novel enzyme with different distribution and specificities.

O14669	TMG2_HUMAN	Transmembrane gamma-carboxyglutamic acid protein 2	9256434	Primary structure and tissue distribution of two novel proline-rich gamma-carboxyglutamic acid proteins.

Q00325	MPCP_HUMAN	Phosphate carrier protein, mitochondrial	1777677	Nucleotide sequence of a human heart cDNA encoding the mitochondrial phosphate carrier.

B8ZXI1	QTRD1_MOUSE	Queuine tRNA-ribosyltransferase subunit QTRTD1	19414587	Queuosine formation in eukaryotic tRNA occurs via a mitochondria- localized heteromeric transglycosylase.

Q03173	ENAH_MOUSE	Protein enabled homolog	8861907	Mena, a relative of VASP and Drosophila Enabled, is implicated in the control of microfilament dynamics.

Q9Y248	PSF2_HUMAN	DNA replication complex GINS protein PSF2	17525332	ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

P91001	CSN5_CAEEL	COP9 signalosome complex subunit 5	12435362	The GLH proteins, Caenorhabditis elegans P granule components, associate with CSN-5 and KGB-1, proteins necessary for fertility, and with ZYX-1, a predicted cytoskeletal protein.

Q03818	ATG16_YEAST	Autophagy protein 16	10406794	Apg16p is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.

Q811U3	RB6I2_RAT	ELKS/Rab6-interacting/CAST family member 1	12391317	A family of RIM-binding proteins regulated by alternative splicing: Implications for the genesis of synaptic active zones.

Q8VI36	PAXI_MOUSE	Paxillin	11825902	Linkage of caspase-mediated degradation of paxillin to apoptosis in Ba/F3 murine pro-B lymphocytes.

P22265	TSH_DROME	Protein teashirt	9707400	Trunk-specific modulation of wingless signalling in Drosophila by teashirt binding to armadillo.

O65719	HSP73_ARATH	Heat shock cognate 70 kDa protein 3	20543027	The deubiquitinating enzyme AMSH3 is required for intracellular trafficking and vacuole biogenesis in Arabidopsis thaliana.

Q92786	PROX1_HUMAN	Prospero homeobox protein 1	8812486	Structure and chromosomal localization of the human homeobox gene Prox 1.

Q86AV6	CISYC_DICDI	Citrate synthase	15225305	Disruption of the peroxisomal citrate synthase CshA affects cell growth and multicellular development in Dictyostelium discoideum.

Q9Y1W0	FAD5A_DICDI	Delta(5) fatty acid desaturase A	10504413	Identification of Delta5-fatty acid desaturase from the cellular slime mold Dictyostelium discoideum.

Q07688	YPD1_YEAST	Phosphorelay intermediate protein YPD1	8808622	Yeast HOG1 MAP kinase cascade is regulated by a multistep phosphorelay mechanism in the SLN1-YPD1-SSK1 two-component osmosensor.

Q96EZ8	MCRS1_HUMAN	Microspherule protein 1	15960975	Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

P19516	COX11_YEAST	Cytochrome c oxidase assembly protein COX11, mitochondrial	2167832	Cytochrome oxidase assembly in yeast requires the product of COX11, a homolog of the P. denitrificans protein encoded by ORF3.

A4GSN8	NUA_ARATH	Nuclear-pore anchor	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

O96019	ACL6A_HUMAN	Actin-like protein 6A	9845365	Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling.

Q9FYC2	PAO_ARATH	Pheophorbide a oxygenase, chloroplastic	14657372	Chlorophyll breakdown: pheophorbide a oxygenase is a Rieske-type iron-sulfur protein, encoded by the accelerated cell death 1 gene.

O60869	EDF1_HUMAN	Endothelial differentiation-related factor 1	10567391	The role of human MBF1 as a transcriptional coactivator.

Q96BI1	S22AI_HUMAN	Solute carrier family 22 member 18	9499412	IMPT1, an imprinted gene similar to polyspecific transporter and multi-drug resistance genes.

Q08746	RRS1_YEAST	Regulator of ribosome biosynthesis	10688653	RRS1, a conserved essential gene, encodes a novel regulatory protein required for ribosome biogenesis in Saccharomyces cerevisiae.

P57735	RAB25_HUMAN	Ras-related protein Rab-25	15502842	The RAB25 small GTPase determines aggressiveness of ovarian and breast cancers.

Q9NSA3	CNBP1_HUMAN	Beta-catenin-interacting protein 1	12408824	The crystal structure of the beta-catenin/ICAT complex reveals the inhibitory mechanism of ICAT.

P29084	T2EB_HUMAN	Transcription initiation factor IIE subunit beta	1956398	Structure and functional properties of human general transcription factor IIE.

P24394	IL4RA_HUMAN	Interleukin-4 receptor subunit alpha	2307934	Human interleukin 4 receptor confers biological responsiveness and defines a novel receptor superfamily.

Q0WMY5	PP365_ARATH	Pentatricopeptide repeat-containing protein At5g04810, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q5W7F1	ASAH2_DANRE	Neutral ceramidase	15271994	Molecular cloning and functional analysis of zebrafish neutral ceramidase.

Q3TTA7	CBLB_MOUSE	E3 ubiquitin-protein ligase CBL-B	11070165	Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells.

P53507	TOM7_YEAST	Mitochondrial import receptor subunit TOM7	9774667	Preprotein translocase of the outer mitochondrial membrane: molecular dissection and assembly of the general import pore complex.

P62487	RPB7_HUMAN	DNA-directed RNA polymerase II subunit RPB7	9852112	Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.

P62651	ERI1_YEAST	Phosphatidylinositol N-acetylglucosaminyltransferase ERI1 subunit	12832483	A novel Ras inhibitor, Eri1, engages yeast Ras at the endoplasmic reticulum.

P43596	IOC3_YEAST	ISWI one complex protein 3	12482963	Yeast Isw1p forms two separable complexes in vivo.

Q6IVW0	IFT57_DANRE	Intraflagellar transport protein 57 homolog	15182712	Intraflagellar transport genes are essential for differentiation and survival of vertebrate sensory neurons.

Q03233	ADD37_YEAST	Alpha1-proteinase inhibitor-degradation deficient protein 37	12711700	Differential requirements of novel A1PiZ degradation deficient (ADD) genes in ER-associated protein degradation.

Q9LW29	AFB2_ARATH	Protein AUXIN SIGNALING F-BOX 2	15992545	Plant development is regulated by a family of auxin receptor F box proteins.

Q04751	NAT4_YEAST	Histone-specific N-acetyltransferase NAT4	14562095	Global analysis of protein localization in budding yeast.

P38159	HNRPG_HUMAN	Heterogeneous nuclear ribonucleoprotein G	7692398	hnRNP G: sequence and characterization of a glycosylated RNA-binding protein.

Q02455	MLP1_YEAST	Protein MLP1	14718167	Nuclear retention of unspliced mRNAs in yeast is mediated by perinuclear Mlp1.

Q6RT24	CENPE_MOUSE	Centromere-associated protein E	12361599	Unstable kinetochore-microtubule capture and chromosomal instability following deletion of CENP-E.

Q9SU13	FLA2_ARATH	Fasciclin-like arabinogalactan protein 2	14517339	Proteomic analysis of glycosylphosphatidylinositol-anchored membrane proteins.

O94286	MTND_SCHPO	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P83280	FAR7_MACRS	FMRFamide-like neuropeptide FLP7	11179812	Three more novel FMRFamide-like neuropeptide sequences from the eyestalk of the giant freshwater prawn Macrobrachium rosenbergii.

Q9C469	GRT1_SCHPO	Zinc finger protein grt1	11058086	High dosage expression of a zinc finger protein, Grt1, suppresses a mutant of fission yeast slp1(+), a homolog of CDC20/p55CDC/Fizzy.

O15061	SYNEM_HUMAN	Synemin	14552890	Synemin expression in developing normal and pathological human retina and lens.

P56270	MAZ_HUMAN	Myc-associated zinc finger protein	1502157	MAZ, a zinc finger protein, binds to c-MYC and C2 gene sequences regulating transcriptional initiation and termination.

P54939	TLN1_CHICK	Talin-1	12535520	Structural determinants of integrin recognition by talin.

Q76FK4	NOL8_HUMAN	Nucleolar protein 8	14660641	A novel human nucleolar protein, Nop132, binds to the G proteins, RRAG A/C/D.

Q24342	FNG_DROME	Fringe glycosyltransferase	10935626	Fringe is a glycosyltransferase that modifies Notch.

Q9NHE5	CAPS_DROME	Calcium-dependent secretion activator	11516399	Drosophila CAPS is an essential gene that regulates dense-core vesicle release and synaptic vesicle fusion.

O96007	MOC2B_HUMAN	Molybdopterin synthase catalytic subunit	12732628	Mechanistic studies of human molybdopterin synthase reaction and characterization of mutants identified in group B patients of molybdenum cofactor deficiency.

Q9Y4Z0	LSM4_HUMAN	U6 snRNA-associated Sm-like protein LSm4	10523320	A doughnut-shaped heteromer of human Sm-like proteins binds to the 3'-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro.

P29703	FNTA_YEAST	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	1763050	RAM2, an essential gene of yeast, and RAM1 encode the two polypeptide components of the farnesyltransferase that prenylates a-factor and Ras proteins.

Q93794	SEL10_CAEEL	F-box/WD repeat-containing protein sel-10	9389650	sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins.

Q92905	CSN5_HUMAN	COP9 signalosome complex subunit 5	9341143	Structure of cDNAs encoding human eukaryotic initiation factor 3 subunits. Possible roles in RNA binding and macromolecular assembly.

Q9FLB1	PYL5_ARATH	Abscisic acid receptor PYL5	19898420	A gate-latch-lock mechanism for hormone signalling by abscisic acid receptors.

P36118	NTR2_YEAST	Pre-mRNA-splicing factor NTR2	16357217	Spliceosome disassembly catalyzed by Prp43 and its associated components Ntr1 and Ntr2.

Q13829	BACD2_HUMAN	BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2	19637314	RhoB induces apoptosis via direct interaction with TNFAIP1 in HeLa cells.

Q86UX7	URP2_HUMAN	Fermitin family homolog 3	19234460	A point mutation in KINDLIN3 ablates activation of three integrin subfamilies in humans.

Q9UID3	FFR_HUMAN	Protein fat-free homolog	9615229	Identification and molecular characterization of TM7SF2 in the FAUNA gene cluster on human chromosome 11q13.

Q99MD9	NASP_MOUSE	Nuclear autoantigenic sperm protein	12509435	Overexpression of the linker histone-binding protein tNASP affects progression through the cell cycle.

P04553	HSP1_HUMAN	Sperm protamine P1	2081589	Genomic sequences of human protamines whose genes, PRM1 and PRM2, are clustered.

Q99MV1	TDRD1_MOUSE	Tudor domain-containing protein 1	19465913	Loss of the Mili-interacting Tudor domain-containing protein-1 activates transposons and alters the Mili-associated small RNA profile.

P17677	NEUM_HUMAN	Neuromodulin	3272162	Human GAP-43: its deduced amino acid sequence and chromosomal localization in mouse and human.

Q14160	SCRIB_HUMAN	Protein scribble homolog	15182672	Mammalian Scribble forms a tight complex with the betaPIX exchange factor.

Q10424	ZIP1_SCHPO	Transcription factor zip1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9V6K3	ROR2_DROME	Tyrosine-protein kinase transmembrane receptor Ror2	9115253	A novel Drosophila receptor tyrosine kinase expressed specifically in the nervous system. Unique structural features and implication in developmental signaling.

P61073	CXCR4_HUMAN	C-X-C chemokine receptor type 4	8276799	Cloning of a human seven-transmembrane domain receptor, LESTR, that is highly expressed in leukocytes.

P53379	MKC7_YEAST	Aspartic proteinase MKC7	10446224	Purification and characterization of the yeast glycosylphosphatidylinositol-anchored, monobasic-specific aspartyl protease yapsin 2 (Mkc7p).

C6KI89	CTSRG_MOUSE	Cation channel sperm-associated protein subunit gamma	19516020	A novel, single, transmembrane protein CATSPERG is associated with CATSPER1 channel protein.

P02452	CO1A1_HUMAN	Collagen alpha-1(I) chain	17211858	Three arginine to cysteine substitutions in the pro-alpha (I)- collagen chain cause Ehlers-Danlos syndrome with a propensity to arterial rupture in early adulthood.

O77059	CRY1_DROME	Cryptochrome-1	9845370	The cryb mutation identifies cryptochrome as a circadian photoreceptor in Drosophila.

Q8R413	PROK2_RAT	Prokineticin-2	12054613	Isolation and identification of EG-VEGF/prokineticins as cognate ligands for two orphan G-protein-coupled receptors.

P10181	ROUGH_DROME	Homeobox protein rough	1974228	The homeo domain protein rough is expressed in a subset of cells in the developing Drosophila eye where it can specify photoreceptor cell subtype.

O43819	SCO2_HUMAN	Protein SCO2 homolog, mitochondrial	10545952	Fatal infantile cardioencephalomyopathy with COX deficiency and mutations in SCO2, a COX assembly gene.

Q05166	NUP59_YEAST	Nucleoporin ASM4	9864357	Specific binding of the karyopherin Kap121p to a subunit of the nuclear pore complex containing Nup53p, Nup59p, and Nup170p.

Q9V674	CP6G1_DROME	Cytochrome P450 6g1	12351787	A single P450 allele associated with insecticide resistance in Drosophila.

Q03036	IRC4_YEAST	Uncharacterized protein IRC4	14562095	Global analysis of protein localization in budding yeast.

P06211	ESR1_RAT	Estrogen receptor	11818503	The activating enzyme of NEDD8 inhibits steroid receptor function.

Q15257	PTPA_HUMAN	Serine/threonine-protein phosphatase 2A activator	17333320	Overexpression of the cis/trans isomerase PTPA triggers caspase 3- dependent apoptosis.

Q03070	CHIO_RAT	Beta-chimaerin	8440677	Germ cell beta-chimaerin, a new GTPase-activating protein for p21rac, is specifically expressed during the acrosomal assembly stage in rat testis.

Q55BZ4	PCY2_DICDI	Ethanolamine-phosphate cytidylyltransferase	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P14127	RS17B_YEAST	40S ribosomal protein S17-B	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q7ZY81	NPL1B_XENLA	Nucleosome assembly protein 1-like 1-B	15928086	Nucleosome assembly protein-1 is a linker histone chaperone in Xenopus eggs.

Q9US25	HRP1_SCHPO	Chromodomain helicase hrp1	10756203	Fission yeast hrp1, a chromodomain ATPase, is required for proper chromosome segregation and its overexpression interferes with chromatin condensation.

Q03981	CSN9_YEAST	COP9 signalosome complex subunit 9	12186635	Conservation of the COP9/signalosome in budding yeast.

Q09T02	MICA_CLAMM	Lantibiotic michiganin-A	16957199	Purification, characterization, and gene sequence of michiganin A, an actagardine-like lantibiotic produced by the tomato pathogen Clavibacter michiganensis subsp. michiganensis.

Q9ZTX8	ARFF_ARATH	Auxin response factor 6	16107481	Auxin response factors ARF6 and ARF8 promote jasmonic acid production and flower maturation.

P38298	YPC1_YEAST	Alkaline ceramidase YPC1	10702247	Cloning of an alkaline ceramidase from Saccharomyces cerevisiae. An enzyme with reverse (CoA-independent) ceramide synthase activity.

Q5BMR2	PLD_PHYIN	Phospholipase D	15826868	A transmembrane phospholipase D in Phytophthora; a novel PLD subfamily.

Q00005	2ABB_HUMAN	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform	1849734	Structure of the 55-kDa regulatory subunit of protein phosphatase 2A: evidence for a neuronal-specific isoform.

P38928	AXL2_YEAST	Protein AXL2	11313501	A GDP/GTP exchange factor involved in linking a spatial landmark to cell polarity.

Q8NFA0	UBP32_HUMAN	Ubiquitin carboxyl-terminal hydrolase 32	20549504	USP32 is an active, membrane-bound ubiquitin protease overexpressed in breast cancers.

Q9NRR4	RNC_HUMAN	Ribonuclease 3	18632581	The FHA domain proteins DAWDLE in Arabidopsis and SNIP1 in humans act in small RNA biogenesis.

Q9NR50	EI2BG_HUMAN	Translation initiation factor eIF-2B subunit gamma	10900014	Identification of eIF2B gamma and eIF2 gamma as cofactors of hepatitis C virus internal ribosome entry site-mediated translation using a functional genomics approach.

Q93249	CAB1_CAEEL	Protein cab-1	10970871	The rab3 GDP/GTP exchange factor homolog AEX-3 has a dual function in synaptic transmission.

Q9HC77	CENPJ_HUMAN	Centromere protein J	17681131	Plk4-induced centriole biogenesis in human cells.

Q8IRY7	CASP8_DROME	Caspase-8	11269502	The Drosophila caspase Dredd is required to resist Gram-negative bacterial infection.

P26022	PTX3_HUMAN	Pentraxin-related protein PTX3	1429570	Interleukin-1-inducible genes in endothelial cells. Cloning of a new gene related to C-reactive protein and serum amyloid P component.

P47149	NNF1_YEAST	Kinetochore-associated protein NNF1	14633972	Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes.

Q9EQU3	TLR9_MOUSE	Toll-like receptor 9	18305481	UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes.

Q24119	TRH_DROME	Protein trachealess	8557198	Trachealess encodes a bHLH-PAS protein that is an inducer of tracheal cell fates in Drosophila.

P32600	TOR2_YEAST	Serine/threonine-protein kinase TOR2	10973982	HEAT repeats mediate plasma membrane localization of Tor2p in yeast.

Q9USS0	PNC1_SCHPO	Nicotinamidase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NJG9	SUZ12_DROME	Polycomb protein Su(z)12	12408863	Drosophila Enhancer of zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites.

Q9LDI3	CIPKO_ARATH	CBL-interacting serine/threonine-protein kinase 24	14504388	A novel domain in the protein kinase SOS2 mediates interaction with the protein phosphatase 2C ABI2.

Q16543	CDC37_HUMAN	Hsp90 co-chaperone Cdc37	9150368	Interaction between Cdc37 and Cdk4 in human cells.

P02794	FRIH_HUMAN	Ferritin heavy chain	6589621	Isolation and characterization of a cDNA clone for human ferritin heavy chain.

P25539	RIBD_ECOLI	Riboflavin biosynthesis protein ribD	9068650	Biosynthesis of riboflavin: characterization of the bifunctional deaminase-reductase of Escherichia coli and Bacillus subtilis.

P00338	LDHA_HUMAN	L-lactate dehydrogenase A chain	1953713	Analysis of genetic mutations in human lactate dehydrogenase-A(M) deficiency using DNA conformation polymorphism in combination with polyacrylamide gradient gel and silver staining.

P43569	CAF16_YEAST	CCR4-associated factor 16	11113136	Characterization of CAF4 and CAF16 reveals a functional connection between the CCR4-NOT complex and a subset of SRB proteins of the RNA polymerase II holoenzyme.

Q90336	MK14A_CYPCA	Mitogen-activated protein kinase 14A	10880959	Identification of a nuclear export signal in MKK6, an activator of the carp p38 mitogen-activated protein kinases.

Q6R0H1	LHY_ARATH	Protein LHY	19286557	A functional genomics approach reveals CHE as a component of the Arabidopsis circadian clock.

O14253	NCBP1_SCHPO	Nuclear cap-binding protein subunit 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P36013	MAOM_YEAST	NAD-dependent malic enzyme, mitochondrial	9603875	Identification and characterization of MAE1, the Saccharomyces cerevisiae structural gene encoding mitochondrial malic enzyme.

P46087	NOP2_HUMAN	Putative ribosomal RNA methyltransferase NOP2	1394192	A region of antisense RNA from human p120 cDNA with high homology to mouse p120 cDNA inhibits NIH 3T3 proliferation.

Q9QYH1	MPP4_RAT	MAGUK p55 subfamily member 4	10558890	rDLG6: a novel homolog of Drosophila DLG expressed in rat brain.

P22265	TSH_DROME	Protein teashirt	10842058	Proximal distal axis formation in the Drosophila leg: distinct functions of teashirt and homothorax in the proximal leg.

O08843	LST1_MOUSE	Leukocyte-specific transcript 1 protein	11478849	Functional analysis of B144/LST1: a gene in the tumor necrosis factor cluster that induces formation of long filopodia in eukaryotic cells.

P53350	PLK1_HUMAN	Serine/threonine-protein kinase PLK1	17495026	The tumor suppressor CYLD regulates entry into mitosis.

Q9Z173	LPHN3_RAT	Latrophilin-3	10026162	A novel ubiquitously expressed alpha-latrotoxin receptor is a member of the CIRL family of G-protein-coupled receptors.

P30052	SCAL_DROME	Protein scalloped	12782275	Further developmental roles of the vestigial/scalloped transcription complex during wing development in Drosophila melanogaster.

O43181	NDUS4_HUMAN	NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

Q9BZM6	N2DL1_HUMAN	NKG2D ligand 1	11239445	ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor.

P39731	MTW1_YEAST	Kinetochore-associated protein MTW1	12455957	Nnf1p, Dsn1p, Mtw1p, and Nsl1p: a new group of proteins important for chromosome segregation in Saccharomyces cerevisiae.

Q12246	LCB4_YEAST	Sphingoid long chain base kinase 4	12459470	Lcb4p sphingoid base kinase localizes to the Golgi and late endosomes.

Q05931	HSP7Q_YEAST	Heat shock protein SSQ1, mitochondrial	12756240	Ssq1, a mitochondrial Hsp70 involved in iron-sulfur (Fe/S) center biogenesis. Similarities to and differences from its bacterial counterpart.

O00910	STATA_DICDI	Signal transducer and activator of transcription A	15053873	Structure of an activated Dictyostelium STAT in its DNA-unbound form.

Q9BW91	NUDT9_HUMAN	ADP-ribose pyrophosphatase, mitochondrial	11385575	ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology.

P53202	CUL3_YEAST	Cullin-3	12676951	A role for Saccharomyces cerevisiae Cul8 ubiquitin ligase in proper anaphase progression.

Q645N4	PAX3A_XENLA	Paired box protein Pax-3-A	15691759	Msx1 and Pax3 cooperate to mediate FGF8 and WNT signals during Xenopus neural crest induction.

P60879	SNP25_MOUSE	Synaptosomal-associated protein 25	17055430	Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse.

P47727	CBR1_RAT	Carbonyl reductase [NADPH] 1	7705364	Cloning and expression of carbonyl reductase from rat testis.

Q9LSD5	TCP20_ARATH	Transcription factor TCP20	12631321	Internal telomeric repeats and 'TCP domain' protein-binding sites co- operate to regulate gene expression in Arabidopsis thaliana cycling cells.

P43487	RANG_HUMAN	Ran-specific GTPase-activating protein	7616957	RanBP1, a Ras-like nuclear G protein binding to Ran/TC4, inhibits RCC1 via Ran/TC4.

Q9UBX0	HESX1_HUMAN	Homeobox expressed in ES cells 1	9620767	Mutations in the homeobox gene HESX1/Hesx1 associated with septo- optic dysplasia in human and mouse.

Q03532	HAS1_YEAST	ATP-dependent RNA helicase HAS1	15049817	Has1p, a member of the DEAD-box family, is required for 40S ribosomal subunit biogenesis in Saccharomyces cerevisiae.

P42571	PO2F3_RAT	POU domain, class 2, transcription factor 3	7682011	Skn-1a and Skn-1i: two functionally distinct Oct-2-related factors expressed in epidermis.

P50542	PEX5_HUMAN	Peroxisomal targeting signal 1 receptor	10562279	PEX12 interacts with PEX5 and PEX10 and acts downstream of receptor docking in peroxisomal matrix protein import.

P36041	EAP1_YEAST	Protein EAP1	10848587	Eap1p, a novel eukaryotic translation initiation factor 4E-associated protein in Saccharomyces cerevisiae.

Q54JH4	P2XE_DICDI	P2X receptor E	19833731	Functional characterization of intracellular Dictyostelium discoideum P2X receptors.

Q9UJU6	DBNL_HUMAN	Drebrin-like protein	10567356	A novel src homology 3 domain-containing adaptor protein, HIP-55, that interacts with hematopoietic progenitor kinase 1.

P53927	NOP15_YEAST	Ribosome biogenesis protein 15	10953080	Gene disruption and basic phenotypic analysis of nine novel yeast genes from chromosome XIV.

P53323	BUD32_YEAST	Serine/threonine-protein kinase BUD32	16874308	Yeast homolog of a cancer-testis antigen defines a new transcription complex.

P34223	UBX1_YEAST	UBX domain-containing protein 1	7891699	The Saccharomyces SHP1 gene, which encodes a regulator of phosphoprotein phosphatase 1 with differential effects on glycogen metabolism, meiotic differentiation, and mitotic cell cycle progression.

Q03212	EAR1_YEAST	Protein EAR1	14562095	Global analysis of protein localization in budding yeast.

O88741	GDAP1_MOUSE	Ganglioside-induced differentiation-associated protein 1	10217254	Isolation of 10 differentially expressed cDNAs in differentiated Neuro2a cells induced through controlled expression of the GD3 synthase gene.

O04508	PUP16_ARATH	Probable purine permease 16	10662864	A new family of high-affinity transporters for adenine, cytosine, and purine derivatives in Arabidopsis.

P19541	RDS2_YEAST	Regulator of drug sensitivity 2	14562095	Global analysis of protein localization in budding yeast.

P18075	BMP7_HUMAN	Bone morphogenetic protein 7	2357959	OP-1 cDNA encodes an osteogenic protein in the TGF-beta family.

P54868	HMCS2_HUMAN	Hydroxymethylglutaryl-CoA synthase, mitochondrial	11479731	Genetic basis of mitochondrial HMG-CoA synthase deficiency.

Q9JMC1	PI5PA_RAT	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A	10593988	Novel inositol polyphosphate 5-phosphatase localizes at membrane ruffles.

P06239	LCK_HUMAN	Tyrosine-protein kinase Lck	8618896	Phosphotyrosine-independent binding of a 62-kDa protein to the src homology 2 (SH2) domain of p56lck and its regulation by phosphorylation of Ser-59 in the lck unique N-terminal region.

P30101	PDIA3_HUMAN	Protein disulfide-isomerase A3	9399589	Functions of characteristic Cys-Gly-His-Cys (CGHC) and Gln-Glu-Asp- Leu (QEDL) motifs of microsomal ER-60 protease.

Q9M2Z4	MSBP2_ARATH	Membrane steroid-binding protein 2	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

O61125	STK4_DICDI	Serine/threonine-protein kinase 4 homolog A	17362909	A stress response kinase, KrsA, controls cAMP relay during the early development of Dictyostelium discoideum.

P37012	PGM2_YEAST	Phosphoglucomutase-2	8119301	A family of hexosephosphate mutases in Saccharomyces cerevisiae.

Q08649	ESA1_YEAST	Histone acetyltransferase ESA1	15949446	Dynamic lysine methylation on histone H3 defines the regulatory phase of gene transcription.

P85871	COSR2_CONSP	Conorfamide-Sr2	18201803	Conorfamide-Sr2, a gamma-carboxyglutamate-containing FMRFamide- related peptide from the venom of Conus spurius with activity in mice and mollusks.

Q9UUF1	YNF8_SCHPO	Deoxyribonuclease Tat-D	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P06700	SIR2_YEAST	NAD-dependent histone deacetylase SIR2	9122169	Silent information regulator protein complexes in Saccharomyces cerevisiae: a SIR2/SIR4 complex and evidence for a regulatory domain in SIR4 that inhibits its interaction with SIR3.

Q9NX09	DDIT4_HUMAN	DNA damage-inducible transcript 4 protein	12453409	REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species.

P42641	OBG_ECOLI	GTPase ObgE/CgtA	11555285	Deficiency of essential GTP-binding protein ObgE in Escherichia coli inhibits chromosome partition.

Q8R2F2	DEGS2_MOUSE	Sphingolipid delta(4)-desaturase/C4-hydroxylase DES2	15474011	Identification of an essential sequence for dihydroceramide C-4 hydroxylase activity of mouse DES2.

P53303	ZPR1_YEAST	Zinc finger protein ZPR1	9852145	Interaction of ZPR1 with translation elongation factor-1alpha in proliferating cells.

Q60631	GRB2_MOUSE	Growth factor receptor-bound protein 2	19597498	Themis, a T cell-specific protein important for late thymocyte development.

P43626	KI2L1_HUMAN	Killer cell immunoglobulin-like receptor 2DL1	7749980	Molecular clones of the p58 NK cell receptor reveal immunoglobulin- related molecules with diversity in both the extra- and intracellular domains.

Q15075	EEA1_HUMAN	Early endosome antigen 1	9697774	EEA1 links PI(3)K function to Rab5 regulation of endosome fusion.

Q07817	B2CL1_HUMAN	Bcl-2-like protein 1	11463391	PUMA induces the rapid apoptosis of colorectal cancer cells.

Q7PIR5	TRET1_ANOGA	Facilitated trehalose transporter Tret1	20035867	The trehalose transporter 1 gene sequence is conserved in insects and encodes proteins with different kinetic properties involved in trehalose import into peripheral tissues.

P38315	YBP1_YEAST	YAP1-binding protein 1	11283351	A comprehensive two-hybrid analysis to explore the yeast protein interactome.

Q9Y466	NR2E1_HUMAN	Nuclear receptor subfamily 2 group E member 1	9628820	The human homologue of the Drosophila tailless gene (TLX): characterization and mapping to a region of common deletion in human lymphoid leukemia on chromosome 6q21.

Q99871	HAUS7_HUMAN	HAUS augmin-like complex subunit 7	19369198	The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells.

Q15796	SMAD2_HUMAN	Mothers against decapentaplegic homolog 2	15647271	The integral inner nuclear membrane protein MAN1 physically interacts with the R-Smad proteins to repress signaling by the transforming growth factor-{beta} superfamily of cytokines.

Q8NG08	HELB_HUMAN	DNA helicase B	12181327	A dominant-negative mutant of human DNA helicase B blocks the onset of chromosomal DNA replication.

Q12952	FOXL1_HUMAN	Forkhead box protein L1	7957066	Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending.

Q6DE08	AUKBA_XENLA	Serine/threonine-protein kinase 12-A	11350965	Chromatin-associated protein phosphatase 1 regulates aurora-B and histone H3 phosphorylation.

O42857	NPR2_SCHPO	Nitrogen permease regulator 2 homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P83259	TXDP4_PIRLC	Delta-amaurobitoxin-Pl1d	10971590	Isolation, synthesis and pharmacological characterization of delta- palutoxins IT, novel insecticidal toxins from the spider Paracoelotes luctuosus (Amaurobiidae).

Q03860	TVP15_YEAST	Golgi apparatus membrane protein TVP15	14562095	Global analysis of protein localization in budding yeast.

Q12888	TP53B_HUMAN	Tumor suppressor p53-binding protein 1	9748285	Stimulation of p53-mediated transcriptional activation by the p53- binding proteins, 53BP1 and 53BP2.

P32333	MOT1_YEAST	TATA-binding protein-associated factor MOT1	12805227	High-affinity DNA binding by a Mot1p-TBP complex: implications for TAF-independent transcription.

P21333	FLNA_HUMAN	Filamin-A	16862148	FilGAP, a Rho- and ROCK-regulated GAP for Rac binds filamin A to control actin remodelling.

Q8CG09	MRP1_RAT	Multidrug resistance-associated protein 1	12867490	Molecular cloning and pharmacological characterization of rat multidrug resistance protein 1 (mrp1).

Q8TAC9	SCAM5_HUMAN	Secretory carrier-associated membrane protein 5	15840657	Secretory carrier membrane proteins interact and regulate trafficking of the organellar (Na+,K+)/H+ exchanger NHE7.

Q9FKW0	RNG1A_ARATH	Putative E3 ubiquitin-protein ligase RING1a	19097900	Polycomb silencing of KNOX genes confines shoot stem cell niches in Arabidopsis.

Q9HC98	NEK6_HUMAN	Serine/threonine-protein kinase Nek6	14563848	The serine/threonine kinase Nek6 is required for cell cycle progression through mitosis.

P03182	EAR_EBVB9	Apoptosis regulator BHRF1	16963744	Human cellular protein VRK2 interacts specifically with Epstein-Barr virus BHRF1, a homologue of Bcl-2, and enhances cell survival.

P41964	DMYC_DROME	Drosomycin	7806546	Insect immunity. Septic injury of Drosophila induces the synthesis of a potent antifungal peptide with sequence homology to plant antifungal peptides.

P20009	DLL_DROME	Homeotic protein distal-less	9303541	The homeobox gene Distal-less induces ventral appendage development in Drosophila.

Q10714	ACE_DROME	Angiotensin-converting enzyme	7775412	Cloning and expression of an evolutionary conserved single-domain angiotensin converting enzyme from Drosophila melanogaster.

Q6VY05	DND1_MOUSE	Dead end protein homolog 1	15902260	The Ter mutation in the dead end gene causes germ cell loss and testicular germ cell tumours.

Q9QXW4	FSCN3_MOUSE	Fascin-3	11925108	Testis fascin (FSCN3): a novel paralog of the actin-bundling protein fascin expressed specifically in the elongate spermatid head.

Q9UI30	TR112_HUMAN	tRNA methyltransferase 112 homolog	18539146	HemK2 protein, encoded on human chromosome 21, methylates translation termination factor eRF1.

Q06488	RSC2_YEAST	Chromatin structure-remodeling complex subunit RSC2	12024034	RSC2, encoding a component of the RSC nucleosome remodeling complex, is essential for 2 micrometer plasmid maintenance in Saccharomyces cerevisiae.

P85509	CBG50_UNIPI	Calcium-binding shell glycoprotein P50	18810748	Nacre calcification in the freshwater mussel Unio pictorum: carbonic anhydrase activity and purification of a 95 kDa calcium-binding glycoprotein.

Q94B74	NUDT2_ARATH	Nudix hydrolase 2	18798872	Overexpression of an ADP-ribose pyrophosphatase, AtNUDX2, confers enhanced tolerance to oxidative stress in Arabidopsis plants.

Q12500	AVL9_YEAST	Late secretory pathway protein AVL9	17229886	Avl9p, a member of a novel protein superfamily, functions in the late secretory pathway.

P01009	A1AT_HUMAN	Alpha-1-antitrypsin	12860985	Canonical inhibitor-like interactions explain reactivity of alpha1- proteinase inhibitor Pittsburgh and antithrombin with proteinases.

P40228	CSK2B_ARATH	Casein kinase II subunit beta	8061317	Isolation of an Arabidopsis thaliana casein kinase II beta subunit by complementation in Saccharomyces cerevisiae.

O00499	BIN1_HUMAN	Myc box-dependent-interacting protein 1	9182667	Amphiphysin II (SH3P9; BIN1), a member of the amphiphysin/Rvs family, is concentrated in the cortical cytomatrix of axon initial segments and nodes of Ranvier in brain and around T tubules in skeletal muscle.

O00160	MYO1F_HUMAN	Myosin-If	9119401	Cloning of the genes encoding two murine and human cochlear unconventional type I myosins.

O95847	UCP4_HUMAN	Mitochondrial uncoupling protein 4	10025957	UCP4, a novel brain-specific mitochondrial protein that reduces membrane potential in mammalian cells.

Q9SY59	NFXL1_ARATH	NF-X1-type zinc finger protein NFXL1	16905136	The AtNFXL1 gene encodes a NF-X1 type zinc finger protein required for growth under salt stress.

O14782	KIF3C_HUMAN	Kinesin-like protein KIF3C	9480755	KIF3C, a novel member of the kinesin superfamily: sequence, expression, and mapping to human chromosome 2 at 2p23.

Q12158	SCC1_YEAST	Sister chromatid cohesion protein 1	11983169	Molecular architecture of SMC proteins and the yeast cohesin complex.

Q9H204	MED28_HUMAN	Mediator of RNA polymerase II transcription subunit 28	15467741	Magicin, a novel cytoskeletal protein associates with the NF2 tumor suppressor merlin and Grb2.

P48539	PCP4_HUMAN	Purkinje cell protein 4	8914602	Molecular genetic characterization and comparative mapping of the human PCP4 gene.

Q9GZV9	FGF23_HUMAN	Fibroblast growth factor 23	11062477	Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23.

Q92905	CSN5_HUMAN	COP9 signalosome complex subunit 5	8837781	A new group of conserved coactivators that increase the specificity of AP-1 transcription factors.

Q16762	THTR_HUMAN	Thiosulfate sulfurtransferase	9070219	Cloning and expression of human liver rhodanese cDNA.

P36617	RAD16_SCHPO	DNA repair protein rad16	8114734	The rad16 gene of Schizosaccharomyces pombe: a homolog of the RAD1 gene of Saccharomyces cerevisiae.

Q62771	STA5A_RAT	Signal transducer and activator of transcription 5A	8584036	Regulation of mammary gland factor/Stat5a during mammary gland development.

Q07798	SPO75_YEAST	Sporulation-specific protein 75	11470404	A screen for genes required for meiosis and spore formation based on whole-genome expression.

Q80WQ9	ZBED4_MOUSE	Zinc finger BED domain-containing protein 4	19369242	ZBED4, a BED-type zinc-finger protein in the cones of the human retina.

P50113	LYS5_YEAST	L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase	10320345	Lysine biosynthesis in Saccharomyces cerevisiae: mechanism of alpha- aminoadipate reductase (Lys2) involves posttranslational phosphopantetheinylation by Lys5.

Q01718	ACTHR_HUMAN	Adrenocorticotropic hormone receptor	1325670	The cloning of a family of genes that encode the melanocortin receptors.

Q9HCJ1	ANKH_HUMAN	Progressive ankylosis protein homolog	11326272	Heterozygous mutations in ANKH, the human ortholog of the mouse progressive ankylosis gene, result in craniometaphyseal dysplasia.

O23680	TOC33_ARATH	Translocase of chloroplast 33, chloroplastic	12766230	Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.

Q14114	LRP8_HUMAN	Low-density lipoprotein receptor-related protein 8	12950167	Domains of apoE required for binding to apoE receptor 2 and to phospholipids: implications for the functions of apoE in the brain.

P0ABM5	CCMD_ECOLI	Heme exporter protein D	7635817	Escherichia coli genes required for cytochrome c maturation.

P54968	ILR1_ARATH	IAA-amino acid hydrolase ILR1	7792599	ILR1, an amidohydrolase that releases active indole-3-acetic acid from conjugates.

P06634	DED1_YEAST	ATP-dependent RNA helicase DED1	9045610	Requirement of the DEAD-Box protein ded1p for messenger RNA translation.

P14598	NCF1_HUMAN	Neutrophil cytosol factor 1	2547247	Recombinant 47-kilodalton cytosol factor restores NADPH oxidase in chronic granulomatous disease.

P04436	TVA1_HUMAN	T-cell receptor alpha chain V region HPB-MLT	6440030	Primary structure of human T-cell receptor alpha-chain.

P53845	YIF1_YEAST	Protein transport protein YIF1	15263065	The phox homology (PX) domain protein interaction network in yeast.

O15318	RPC7_HUMAN	DNA-directed RNA polymerase III subunit RPC7	19631370	RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway.

O61661	CHK1_DROME	Serine/threonine-protein kinase grp	12919679	Control of cleavage cycles in Drosophila embryos by fruhstart.

Q9FQ09	KU80_ARATH	ATP-dependent DNA helicase 2 subunit KU80	12182708	Disruption of the Arabidopsis AtKu80 gene demonstrates an essential role for AtKu80 protein in efficient repair of DNA double-strand breaks in vivo.

P55198	AF17_HUMAN	Protein AF-17	8058765	Leucine-zipper dimerization motif encoded by the AF17 gene fused to ALL-1 (MLL) in acute leukemia.

P32119	PRDX2_HUMAN	Peroxiredoxin-2	11904290	Proteomics analysis of cellular response to oxidative stress. Evidence for in vivo overoxidation of peroxiredoxins at their active site.

P62845	RS15_RAT	40S ribosomal protein S15	2044758	Rig encodes ribosomal protein S15. The primary structure of mammalian ribosomal protein S15.

Q8WTP8	AEN_HUMAN	Apoptosis-enhancing nuclease	18264133	p53 target gene AEN is a nuclear exonuclease required for p53- dependent apoptosis.

Q55DH8	CATB_DICDI	Catalase-B	15075287	Identification of genes dependent on the MADS box transcription factor SrfA in Dictyostelium discoideum development.

Q9NR45	SIAS_HUMAN	Sialic acid synthase	10749855	Cloning and expression of the human N-acetylneuraminic acid phosphate synthase gene with 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid biosynthetic ability.

Q9I7U4	TITIN_DROME	Titin	10669599	Sequence and expression of the kettin gene in Drosophila melanogaster and Caenorhabditis elegans.

Q9Y7J1	SPO6_SCHPO	Sporulation-specific protein 6	10886372	The Schizosaccharomyces pombe spo6+ gene encoding a nuclear protein with sequence similarity to budding yeast Dbf4 is required for meiotic second division and sporulation.

Q03144	SNO1_YEAST	Probable glutamine amidotransferase SNO1	12271461	Functional analysis of yeast gene families involved in metabolism of vitamins B1 and B6.

P33240	CSTF2_HUMAN	Cleavage stimulation factor subunit 2	18688255	Conserved motifs in both CPSF73 and CPSF100 are required to assemble the active endonuclease for histone mRNA 3'-end maturation.

P40380	RUM1_SCHPO	Cyclin-dependent kinase inhibitor rum1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P14906	SEC63_YEAST	Protein translocation protein SEC63	15671059	Protein kinase CK2 phosphorylates Sec63p to stimulate the assembly of the endoplasmic reticulum protein translocation apparatus.

O95696	BRD1_HUMAN	Bromodomain-containing protein 1	16387653	ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.

P69850	DAD3_YEAST	DASH complex subunit DAD3	15664196	Formation of a dynamic kinetochore-microtubule interface through assembly of the Dam1 ring complex.

Q8I5R7	SYP_PLAF7	Prolyl-tRNA synthetase	14663147	Trans-editing of mischarged tRNAs.

P01019	ANGT_HUMAN	Angiotensinogen	8513325	A molecular variant of angiotensinogen associated with preeclampsia.

P41800	MMM1_YEAST	Maintenance of mitochondrial morphology protein 1	17410204	The morphology proteins Mdm12/Mmm1 function in the major beta-barrel assembly pathway of mitochondria.

Q86CZ2	DHKK_DICDI	Hybrid signal transduction histidine kinase K	16473345	The histidine kinase homologue DhkK/Sombrero controls morphogenesis in Dictyostelium.

Q8VHZ7	IMP4_MOUSE	U3 small nucleolar ribonucleoprotein protein IMP4	12655004	The human Imp3 and Imp4 proteins form a ternary complex with hMpp10, which only interacts with the U3 snoRNA in 60-80S ribonucleoprotein complexes.

P53236	RSC1_YEAST	Chromatin structure-remodeling complex subunit RSC1	10619019	Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains.

O94812	BAIP3_HUMAN	BAI1-associated protein 3	9790924	Cloning and characterization of BAP3 (BAI-associated protein 3), a C2 domain-containing protein that interacts with BAI1.

Q8CJ00	NOXA1_MOUSE	NADPH oxidase activator 1	12473664	Two novel proteins activate superoxide generation by the NADPH oxidase NOX1.

P39950	CCNG1_RAT	Cyclin-G1	9464250	CyclinG contributes to G2/M arrest of cells in response to DNA damage.

Q13268	DHRS2_HUMAN	Dehydrogenase/reductase SDR family member 2	1847869	Identification of a novel nuclear protein synthesized in growth- arrested human hepatoblastoma HepG2 cells.

Q90X64	VNG2A_XENLA	Vang-like protein 2-A	12941693	Prickle and Strabismus form a functional complex to generate a correct axis during planar cell polarity signaling.

Q99828	CIB1_HUMAN	Calcium and integrin-binding protein 1	10366599	A myristoylated calcium-binding protein that preferentially interacts with the Alzheimer's disease presenilin 2 protein.

Q8R4B8	NALP3_MOUSE	NACHT, LRR and PYD domains-containing protein 3	17008311	Critical role for cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA.

P54284	CACB3_HUMAN	Voltage-dependent L-type calcium channel subunit beta-3	8119293	Cloning, chromosomal location and functional expression of the human voltage-dependent calcium-channel beta 3 subunit.

P41800	MMM1_YEAST	Maintenance of mitochondrial morphology protein 1	13679517	A protein complex containing Mdm10p, Mdm12p, and Mmm1p links mitochondrial membranes and DNA to the cytoskeleton-based segregation machinery.

P49447	CY561_HUMAN	Cytochrome b561	7559396	Genomic structure and expression of the human gene encoding cytochrome b561, an integral protein of the chromaffin granule membrane.

O80920	PYL4_ARATH	Abscisic acid receptor PYL4	19624469	Modulation of drought resistance by the abscisic acid receptor PYL5 through inhibition of clade A PP2Cs.

P00257	ADX_BOVIN	Adrenodoxin, mitochondrial	12069587	A new electron transport mechanism in mitochondrial steroid hydroxylase systems based on structural changes upon the reduction of adrenodoxin.

Q5ADX5	MCES_CANAL	mRNA cap guanine-N7 methyltransferase	10347220	Characterization of human, Schizosaccharomyces pombe, and Candida albicans mRNA cap methyltransferases and complete replacement of the yeast capping apparatus by mammalian enzymes.

Q5SYC1	CLVS2_HUMAN	Clavesin-2	19651769	The clavesin family: neuron-specific lipid- and clathrin-binding Sec14 proteins regulating lysosomal morphology.

P17812	PYRG1_HUMAN	CTP synthase 1	16179339	Expression of human CTP synthetase in Saccharomyces cerevisiae reveals phosphorylation by protein kinase A.

O13821	VPS27_SCHPO	Vacuolar protein sorting-associated protein 27	17660439	Essential roles of class E Vps proteins for sorting into multivesicular bodies in Schizosaccharomyces pombe.

Q9H3Q1	BORG4_HUMAN	Cdc42 effector protein 4	11035016	A new family of Cdc42 effector proteins, CEPs, function in fibroblast and epithelial cell shape changes.

Q6Q788	APOA5_HUMAN	Apolipoprotein A-V	11588264	An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing.

O75602	SPAG6_HUMAN	Sperm-associated antigen 6	10493827	cDNA cloning and characterization of a human sperm antigen (SPAG6) with homology to the product of the Chlamydomonas PF16 locus.

P31688	TPS2_YEAST	Trehalose-phosphatase	8444170	Disruption of TPS2, the gene encoding the 100-kDa subunit of the trehalose-6-phosphate synthase/phosphatase complex in Saccharomyces cerevisiae, causes accumulation of trehalose-6-phosphate and loss of trehalose-6-phosphate phosphatase activity.

Q7T2V3	M3K10_XENLA	Mitogen-activated protein kinase kinase kinase 10	12591241	A tissue restricted role for the Xenopus Jun N-terminal kinase kinase kinase MLK2 in cement gland and pronephric tubule differentiation.

Q92481	AP2B_HUMAN	Transcription factor AP-2-beta	8661133	Chromosomal mapping of the human and mouse homologues of two new members of the AP-2 family of transcription factors.

Q95RU0	CUE_DROME	Protein cueball	8244010	Toward a molecular genetic analysis of spermatogenesis in Drosophila melanogaster: characterization of male-sterile mutants generated by single P element mutagenesis.

P34881	DNMT1_ARATH	DNA (cytosine-5)-methyltransferase 1	16531498	DNA methylation is critical for Arabidopsis embryogenesis and seed viability.

P61320	LOLB_ECOLI	Outer-membrane lipoprotein lolB	9384574	A novel outer membrane lipoprotein, LolB (HemM), involved in the LolA (p20)-dependent localization of lipoproteins to the outer membrane of Escherichia coli.

P00374	DYR_HUMAN	Dihydrofolate reductase	15039552	Structure determination of tetrahydroquinazoline antifolates in complex with human and Pneumocystis carinii dihydrofolate reductase: correlations between enzyme selectivity and stereochemistry.

Q9Y6M9	NDUB9_HUMAN	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

Q92903	CDS1_HUMAN	Phosphatidate cytidylyltransferase 1	9806839	Isolation and chromosomal localization of two human CDP- diacylglycerol synthase (CDS) genes.

Q24572	CAF1_DROME	Probable histone-binding protein Caf1	11533245	Interaction between the Drosophila CAF-1 and ASF1 chromatin assembly factors.

Q9QZH6	ECSIT_MOUSE	Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial	14633973	Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis.

O94643	MIS17_SCHPO	Kinetochore protein mis17	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O88637	PCY2_RAT	Ethanolamine-phosphate cytidylyltransferase	10493918	Cloning and expression of CTP:phosphoethanolamine cytidylyltransferase cDNA from rat liver.

Q9XIE2	AB36G_ARATH	ABC transporter G family member 36	16473969	Arabidopsis PEN3/PDR8, an ATP binding cassette transporter, contributes to nonhost resistance to inappropriate pathogens that enter by direct penetration.

O13744	RT07_SCHPO	37S ribosomal protein S7, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P0A8M3	SYT_ECOLI	Threonyl-tRNA synthetase	10319817	The structure of threonyl-tRNA synthetase-tRNA(Thr) complex enlightens its repressor activity and reveals an essential zinc ion in the active site.

Q6QNY1	BL1S2_HUMAN	Biogenesis of lysosome-related organelles complex 1 subunit 2	15102850	Identification of snapin and three novel proteins (BLOS1, BLOS2, and BLOS3/reduced pigmentation) as subunits of biogenesis of lysosome- related organelles complex-1 (BLOC-1).

Q86WJ1	CHD1L_HUMAN	Chromodomain-helicase-DNA-binding protein 1-like	19661379	Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1.

Q00764	TPS1_YEAST	Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit	9194697	Structural analysis of the subunits of the trehalose-6-phosphate synthase/phosphatase complex in Saccharomyces cerevisiae and their function during heat shock.

Q12374	NCA2_YEAST	Nuclear control of ATPase protein 2	14562095	Global analysis of protein localization in budding yeast.

O88867	KMO_RAT	Kynurenine 3-monooxygenase	1332540	A radiometric assay for kynurenine 3-hydroxylase based on the release of 3H2O during hydroxylation of L-[3,5-3H]kynurenine.

Q05344	SSRP1_DROME	FACT complex subunit Ssrp1	12815073	Drosophila FACT contributes to Hox gene expression through physical and functional interactions with GAGA factor.

P10275	ANDR_HUMAN	Androgen receptor	16051670	hZimp7, a novel PIAS-like protein, enhances androgen receptor- mediated transcription and interacts with SWI/SNF-like BAF complexes.

P0AF12	MTNN_ECOLI	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase	9524204	Cloning and expression of Escherichia coli 5'-methylthioadenosine/S- adenosylhomocysteine nucleosidase: identification of the pfs gene product.

P42776	GBF3_ARATH	G-box-binding factor 3	1373374	Heterodimerization between light-regulated and ubiquitously expressed Arabidopsis GBF bZIP proteins.

Q9QYB1	CLIC4_MOUSE	Chloride intracellular channel protein 4	10593946	p53 and tumor necrosis factor alpha regulate the expression of a mitochondrial chloride channel protein.

P38823	DMA1_YEAST	E3 ubiquitin-protein ligase DMA1	15146058	Functional characterization of Dma1 and Dma2, the budding yeast homologues of Schizosaccharomyces pombe Dma1 and human Chfr.

Q9H1K0	RBNS5_HUMAN	Rabenosyn-5	11062261	Rabenosyn-5, a novel Rab5 effector, is complexed with hVPS45 and recruited to endosomes through a FYVE finger domain.

P20484	MAK11_YEAST	Protein MAK11	2826479	The MAK11 protein is essential for cell growth and replication of M double-stranded RNA and is apparently a membrane-associated protein.

P15428	PGDH_HUMAN	15-hydroxyprostaglandin dehydrogenase [NAD+]	2025296	Site-directed mutagenesis of the conserved tyrosine 151 of human placental NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase yields a catalytically inactive enzyme.

P85216	AP2_GALME	Anionic antimicrobial peptide 2	17194500	Purification and characterization of eight peptides from Galleria mellonella immune hemolymph.

Q9UDV6	ZN212_HUMAN	Zinc finger protein 212	7633419	Rapid isolation and characterization of 118 novel C2H2-type zinc finger cDNAs expressed in human brain.

P41218	MNDA_HUMAN	Myeloid cell nuclear differentiation antigen	1644857	Cloning and expression of the human myeloid cell nuclear differentiation antigen: regulation by interferon alpha.

P84803	CRV24_NAJKA	Cysteine-rich venom protein 24	15670767	Cobra venom contains a pool of cysteine-rich secretory proteins.

Q9BZP6	CHIA_HUMAN	Acidic mammalian chitinase	19435888	Differential enzymatic activity of common haplotypic versions of the human acidic mammalian chitinase protein.

Q42384	PRL1_ARATH	Protein pleiotropic regulatory locus 1	10220464	Regulatory interaction of PRL1 WD protein with Arabidopsis SNF1-like protein kinases.

Q96DB9	FXYD5_HUMAN	FXYD domain-containing ion transport regulator 5	11756660	Dysadherin, a cancer-associated cell membrane glycoprotein, down- regulates E-cadherin and promotes metastasis.

P56179	DLX6_HUMAN	Homeobox protein DLX-6	7907794	Cloning and characterization of two members of the vertebrate Dlx gene family.

P17980	PRS6A_HUMAN	26S protease regulatory subunit 6A	2194290	A cDNA for a protein that interacts with the human immunodeficiency virus Tat transactivator.

Q8LDU4	RCCR_ARATH	Red chlorophyll catabolite reductase, chloroplastic	11149948	The Arabidopsis accelerated cell death gene ACD2 encodes red chlorophyll catabolite reductase and suppresses the spread of disease symptoms.

Q9UQW6	THIL_SCHPO	Acetyl-CoA acetyltransferase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q06667	IPK1_YEAST	Inositol-pentakisphosphate 2-kinase	10960485	Biochemical and functional characterization of inositol 1,3,4,5, 6- pentakisphosphate 2-kinases.

Q9FXD6	ARR11_ARATH	Two-component response regulator ARR11	12610214	In vivo and in vitro characterization of the ARR11 response regulator implicated in the His-to-Asp phosphorelay signal transduction in Arabidopsis thaliana.

Q91ZW3	SMCA5_MOUSE	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5	19092802	WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity.

Q02061	RPB2_SCHPO	DNA-directed RNA polymerase II subunit RPB2	8441660	Cloning and sequence determination of the Schizosaccharomyces pombe rpb2 gene encoding the subunit 2 of RNA polymerase II.

P43572	EPL1_YEAST	Enhancer of polycomb-like protein 1	15485911	The Yaf9 component of the SWR1 and NuA4 complexes is required for proper gene expression, histone H4 acetylation, and Htz1 replacement near telomeres.

P27305	GLUQ_ECOLI	Glutamyl-Q tRNA(Asp) synthetase	15096612	A truncated aminoacyl-tRNA synthetase modifies RNA.

Q8IXJ6	SIRT2_HUMAN	NAD-dependent deacetylase sirtuin-2	16079181	Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins.

P58958	G39AC_DROME	Putative gustatory receptor 39a, isoform D	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

P38304	MED8_YEAST	Mediator of RNA polymerase II transcription subunit 8	9420330	The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain.

Q9UTA0	YEIB_SCHPO	Uncharacterized protein C27E2.11c, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P23883	PUUC_ECOLI	Gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase	15590624	A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.

Q8WTS6	SETD7_HUMAN	Histone-lysine N-methyltransferase SETD7	15525938	Regulation of p53 activity through lysine methylation.

Q12341	HAT1_YEAST	Histone acetyltransferase type B catalytic subunit	15099519	The nuclear Hat1p/Hat2p complex: a molecular link between type B histone acetyltransferases and chromatin assembly.

Q9DBY1	SYVN1_MOUSE	E3 ubiquitin-protein ligase synoviolin	15611074	Essential role of synoviolin in embryogenesis.

Q8WXE9	STON2_HUMAN	Stonin-2	11454741	Human stoned B interacts with AP-2 and synaptotagmin and facilitates clathrin-coated vesicle uncoating.

Q13114	TRAF3_HUMAN	TNF receptor-associated factor 3	10791955	MIP-T3, a novel protein linking tumor necrosis factor receptor- associated factor 3 to the microtubule network.

Q9SS48	SDP6_ARATH	Glycerol-3-phosphate dehydrogenase SDP6, mitochondrial	12586344	Identification of a mitochondrial glycerol-3-phosphate dehydrogenase from Arabidopsis thaliana: evidence for a mitochondrial glycerol-3- phosphate shuttle in plants.

Q12473	FRE6_YEAST	Ferric reductase transmembrane component 6	17553781	Identification of a vacuole-associated metalloreductase and its role in Ctr2-mediated intracellular copper mobilization.

P21369	PNCA_ECOLI	Pyrazinamidase/nicotinamidase	8726014	Identification, cloning, and expression of the Escherichia coli pyrazinamidase and nicotinamidase gene, pncA.

P33570	TKT2_ECOLI	Transketolase 2	8396116	Identification and characterization of the tktB gene encoding a second transketolase in Escherichia coli K-12.

P62253	UB2G1_HUMAN	Ubiquitin-conjugating enzyme E2 G1	20061386	The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.

O13911	PNK1_SCHPO	Bifunctional polynucleotide phosphatase/kinase	11729194	Pnk1, a DNA kinase/phosphatase required for normal response to DNA damage by gamma-radiation or camptothecin in Schizosaccharomyces pombe.

O35413	SRBS2_RAT	Sorbin and SH3 domain-containing protein 2	10521485	nArgBP2, a novel neural member of ponsin/ArgBP2/vinexin family that interacts with synapse-associated protein 90/postsynaptic density-95- associated protein (SAPAP).

Q9M0V3	DDB1A_ARATH	DNA damage-binding protein 1a	16792691	CUL4 associates with DDB1 and DET1 and its downregulation affects diverse aspects of development in Arabidopsis thaliana.

O35789	B3GA1_RAT	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1	9804790	Purification and characterization of a glucuronyltransferase involved in the biosynthesis of the HNK-1 epitope on glycoproteins from rat brain.

Q9NWK9	BCD1_HUMAN	Box C/D snoRNA protein 1	17636026	A dynamic scaffold of pre-snoRNP factors facilitates human box C/D snoRNP assembly.

Q7Z3T8	ZFY16_HUMAN	Zinc finger FYVE domain-containing protein 16	11546807	Endofin, an endosomal FYVE domain protein.

Q8IN81	FRU_DROME	Sex determination protein fruitless	7938017	The BTB domain, found primarily in zinc finger proteins, defines an evolutionarily conserved family that includes several developmentally regulated genes in Drosophila.

P53633	PRA1_YEAST	Prenylated Rab acceptor 1	11785952	Saccharomyces cerevisiae Pra1p/Yip3p interacts with Yip1p and Rab proteins.

Q8LPK5	CESA8_ARATH	Cellulose synthase A catalytic subunit 8 [UDP-forming]	15998313	Disruption of the cellulose synthase gene, AtCesA8/IRX1, enhances drought and osmotic stress tolerance in Arabidopsis.

Q96J01	THOC3_HUMAN	THO complex subunit 3	15833825	Linking transcriptional elongation and messenger RNA export to metastatic breast cancers.

Q15124	PGM5_HUMAN	Phosphoglucomutase-like protein 5	8175905	A novel phosphoglucomutase-related protein is concentrated in adherens junctions of muscle and nonmuscle cells.

Q91Y86	MK08_MOUSE	Mitogen-activated protein kinase 8	11562351	Requirement of the JIP1 scaffold protein for stress-induced JNK activation.

Q9UKX3	MYH13_HUMAN	Myosin-13	10388558	Comparative sequence analysis of the complete human sarcomeric myosin heavy chain family: implications for functional diversity.

Q13616	CUL1_HUMAN	Cullin-1	12504026	CAND1 binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex.

P53350	PLK1_HUMAN	Serine/threonine-protein kinase PLK1	18662541	The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint.

O74943	YJB6_SCHPO	Uncharacterized protein C553.06	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O42916	ALE1_SCHPO	Lysophospholipid acyltransferase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9SU40	SKU5_ARATH	Monocopper oxidase-like protein SKU5	12805588	Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis.

P43593	UBP6_YEAST	Ubiquitin carboxyl-terminal hydrolase 6	11029046	Proteasomal proteomics: identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes.

Q96SW2	CRBN_HUMAN	Protein cereblon	20223979	Identification of a primary target of thalidomide teratogenicity.

P49957	TRM9_YEAST	tRNA (uracil-5-)-methyltransferase TRM9	14645538	Novel methyltransferase for modified uridine residues at the wobble position of tRNA.

P40530	PDK_YEAST	[Pyruvate dehydrogenase [lipoamide]] kinase, mitochondrial	16643908	YIL042c and YOR090c encode the kinase and phosphatase of the Saccharomyces cerevisiae pyruvate dehydrogenase complex.

Q15306	IRF4_HUMAN	Interferon regulatory factor 4	8921401	Cloning of human lymphocyte-specific interferon regulatory factor (hLSIRF/hIRF4) and mapping of the gene to 6p23-p25.

P53958	BOP3_YEAST	Protein BOP3	14562095	Global analysis of protein localization in budding yeast.

Q9D0C1	RN115_MOUSE	E3 ubiquitin-protein ligase RNF115	12972561	Rabring7, a novel Rab7 target protein with a RING finger motif.

Q9SRS9	CHIP_ARATH	E3 ubiquitin-protein ligase CHIP	12805616	AtCHIP, a U-box-containing E3 ubiquitin ligase, plays a critical role in temperature stress tolerance in Arabidopsis.

P01584	IL1B_HUMAN	Interleukin-1 beta	9062193	Crystal structure of the type-I interleukin-1 receptor complexed with interleukin-1beta.

P40075	SCS2_YEAST	Vesicle-associated membrane protein-associated protein SCS2	8537323	Cloning and sequence of the SCS2 gene, which can suppress the defect of INO1 expression in an inositol auxotrophic mutant of Saccharomyces cerevisiae.

O00743	PPP6_HUMAN	Serine/threonine-protein phosphatase 6 catalytic subunit	9013334	The novel human protein serine/threonine phosphatase 6 is a functional homologue of budding yeast Sit4p and fission yeast ppe1, which are involved in cell cycle regulation.

Q9ES70	NEK6_MOUSE	Serine/threonine-protein kinase Nek6	10964517	Isolation and characterization of two evolutionarily conserved murine kinases (Nek6 and Nek7) related to the fungal mitotic regulator, NIMA.

Q06563	SYM1_YEAST	Protein SYM1	15189984	SYM1 is the stress-induced Saccharomyces cerevisiae ortholog of the mammalian kidney disease gene Mpv17 and is required for ethanol metabolism and tolerance during heat shock.

Q12330	RUXE_YEAST	Small nuclear ribonucleoprotein E	9012791	Identification of the proteins of the yeast U1 small nuclear ribonucleoprotein complex by mass spectrometry.

Q9BYE9	CDHR2_HUMAN	Cadherin-related family member 2	12117771	Protocadherin LKC, a new candidate for a tumor suppressor of colon and liver cancers, its association with contact inhibition of cell proliferation.

Q9XI23	BOR4_ARATH	Boron transporter 4	18048682	Plants tolerant of high boron levels.

Q8R316	HBP1_MOUSE	HMG box-containing protein 1	9178770	The HMG-box transcription factor HBP1 is targeted by the pocket proteins and E1A.

Q93594	NCBP2_CAEEL	Nuclear cap-binding protein subunit 2	16207815	Caenorhabditis elegans decapping proteins: localization and functional analysis of Dcp1, Dcp2, and DcpS during embryogenesis.

Q96BI1	S22AI_HUMAN	Solute carrier family 22 member 18	9751628	Somatic mutation of TSSC5, a novel imprinted gene from human chromosome 11p15.5.

P64602	MLAB_ECOLI	Probable phospholipid ABC transporter-binding protein mlaB	19383799	An ABC transport system that maintains lipid asymmetry in the gram- negative outer membrane.

P25615	DPO4_YEAST	DNA polymerase IV	10438542	Efficient processing of DNA ends during yeast nonhomologous end joining. Evidence for a DNA polymerase beta (Pol4)-dependent pathway.

Q558U1	IFKA_DICDI	Probable serine/threonine-protein kinase ifkA	17177855	Disruption of the ifkA and ifkB genes results in altered cell adhesion, morphological defects and a propensity to form pre-stalk O cells during development of Dictyostelium.

Q15828	CYTM_HUMAN	Cystatin-M	9099741	Cystatin E is a novel human cysteine proteinase inhibitor with structural resemblance to family 2 cystatins.

Q800Y1	OSTCN_ARGRE	Osteocalcin	12568402	Purification of matrix Gla protein from a marine teleost fish, Argyrosomus regius: calcified cartilage and not bone as the primary site of MGP accumulation in fish.

Q6QNY0	BL1S3_HUMAN	Biogenesis of lysosome-related organelles complex 1 subunit 3	15102850	Identification of snapin and three novel proteins (BLOS1, BLOS2, and BLOS3/reduced pigmentation) as subunits of biogenesis of lysosome- related organelles complex-1 (BLOC-1).

Q99808	S29A1_HUMAN	Equilibrative nucleoside transporter 1	8986748	Cloning of a human nucleoside transporter implicated in the cellular uptake of adenosine and chemotherapeutic drugs.

O13674	MUG24_SCHPO	Meiotically up-regulated gene 24 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Y275	TN13B_HUMAN	Tumor necrosis factor ligand superfamily member 13B	10359578	BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth.

P47008	SFH5_YEAST	Phosphatidylinositol transfer protein SFH5	10848624	Identification of a novel family of nonclassic yeast phosphatidylinositol transfer proteins whose function modulates phospholipase D activity and Sec14p-independent cell growth.

Q09094	REC15_SCHPO	Meiotic recombination protein rec15	8559063	An intron-containing meiosis-induced recombination gene, rec15, of Schizosaccharomyces pombe.

O02100	HOP1_CAEEL	Presenilin hop-1	9342387	HOP-1, a Caenorhabditis elegans presenilin, appears to be functionally redundant with SEL-12 presenilin and to facilitate LIN-12 and GLP-1 signaling.

P0C1Q4	MASTI_POLPI	Mastoparan-1	16129513	Structural and functional characterization of two novel peptide toxins isolated from the venom of the social wasp Polybia paulista.

Q9UUH7	GYP7_SCHPO	GTPase-activating protein gyp7	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9FT74	RQL1_ARATH	ATP-dependent DNA helicase Q-like 1	12856935	Arabidopsis RecQsim, a plant-specific member of the RecQ helicase family, can suppress the MMS hypersensitivity of the yeast sgs1 mutant.

P83405	SCBT1_BUTJU	Neurotoxin Tx-1	15067003	Activation of skeletal ryanodine receptors by two novel scorpion toxins from Buthotus judaicus.

Q09793	NUP45_SCHPO	Nucleoporin nup45	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O70377	SNP23_RAT	Synaptosomal-associated protein 23	10051443	SNAP-23 participates in SNARE complex assembly in rat adipose cells.

Q7YXU4	CPNA_DICDI	Copine-A	17259548	Copine A is required for cytokinesis, contractile vacuole function, and development in Dictyostelium.

Q5XIC0	PECI_RAT	Peroxisomal 3,2-trans-enoyl-CoA isomerase	11781327	Functional characterization of delta3,delta2-enoyl-CoA isomerases from rat liver.

P11233	RALA_HUMAN	Ras-related protein Ral-A	15809419	Molecular recognition of an ADP-ribosylating Clostridium botulinum C3 exoenzyme by RalA GTPase.

P06318	LV604_HUMAN	Ig lambda chain V-VI region WLT	4089539	Amino acid sequence of a lambda VI primary (AL) amyloid protein (WLT).

P38918	ARK73_RAT	Aflatoxin B1 aldehyde reductase member 3	12727802	Characterization of the rat aflatoxin B1 aldehyde reductase gene, AKR7A1. Structure and chromosomal localization of AKR7A1 as well as identification of antioxidant response elements in the gene promoter.

P20268	HM06_CAEEL	Homeobox protein ceh-6	11171402	Regulation of ectodermal and excretory function by the C. elegans POU homeobox gene ceh-6.

P38817	GGA2_YEAST	ADP-ribosylation factor-binding protein GGA2	10747088	A family of proteins with gamma-adaptin and VHS domains that facilitate trafficking between the trans-Golgi network and the vacuole/lysosome.

Q9Y278	HS3S2_HUMAN	Heparan sulfate glucosamine 3-O-sulfotransferase 2	9988767	Multiple isoforms of heparan sulfate D-glucosaminyl 3-O- sulfotransferase. Isolation, characterization, and expression of human cDNAs and identification of distinct genomic loci.

Q9JHJ1	RAMP2_RAT	Receptor activity-modifying protein 2	11556887	Cloning, characterization and central nervous system distribution of receptor activity modifying proteins in the rat.

Q07889	SOS1_HUMAN	Son of sevenless homolog 1	9790532	Crystal structure of the Dbl and pleckstrin homology domains from the human Son of sevenless protein.

P32904	RM06_YEAST	54S ribosomal protein L6, mitochondrial	12392552	Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components.

Q9ZVH0	FEZ_ARATH	Protein FEZ	19081078	The NAC domain transcription factors FEZ and SOMBRERO control the orientation of cell division plane in Arabidopsis root stem cells.

P38153	AP3M_YEAST	AP-3 complex subunit mu	9335339	The AP-3 adaptor complex is essential for cargo-selective transport to the yeast vacuole.

Q9BPX3	CND3_HUMAN	Condensin complex subunit 3	11136719	Chromosome condensation by a human condensin complex in Xenopus egg extracts.

O94740	CDC37_SCHPO	Hsp90 co-chaperone Cdc37	14652737	Fission yeast Cdc37 is required for multiple cell cycle functions.

Q9C508	PUP18_ARATH	Probable purine permease 18	10662864	A new family of high-affinity transporters for adenine, cytosine, and purine derivatives in Arabidopsis.

P04041	GPX1_RAT	Glutathione peroxidase 1	3408482	Determination of nucleotide sequence of cDNA coding rat glutathione peroxidase and diminished expression of the mRNA in selenium deficient rat liver.

Q99PQ1	TRI12_MOUSE	Tripartite motif-containing protein 12	11331580	The tripartite motif family identifies cell compartments.

O75683	SURF6_HUMAN	Surfeit locus protein 6	10675619	Isolation and genomic analysis of the human surf-6 gene: a member of the Surfeit locus.

O75486	SUPT3_HUMAN	Transcription initiation protein SPT3 homolog	18206972	A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing.

Q12180	HAL9_YEAST	Halotolerance protein 9	9559673	Yeast putative transcription factors involved in salt tolerance.

Q969S0	S35B4_HUMAN	UDP-xylose and UDP-N-acetylglucosamine transporter	15911612	The human solute carrier gene SLC35B4 encodes a bifunctional nucleotide sugar transporter with specificity for UDP-xylose and UDP- N-acetylglucosamine.

O81643	VILI1_ARATH	Villin-1	10631247	Villin-like actin-binding proteins are expressed ubiquitously in Arabidopsis.

Q8IXL7	MSRB3_HUMAN	Methionine-R-sulfoxide reductase B3, mitochondrial	14699060	Methionine sulfoxide reduction in mammals: characterization of methionine-R-sulfoxide reductases.

P93834	HXK2_ARATH	Hexokinase-2	12953116	Enzymes of glycolysis are functionally associated with the mitochondrion in Arabidopsis cells.

P81914	OR33A_DROME	Odorant receptor 33a	10089887	A spatial map of olfactory receptor expression in the Drosophila antenna.

Q9Y6Q9	NCOA3_HUMAN	Nuclear receptor coactivator 3	12917342	BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation.

Q12229	UBX3_YEAST	UBX domain-containing protein 3	14562095	Global analysis of protein localization in budding yeast.

Q07141	TLE4_RAT	Transducin-like enhancer protein 4	8245004	A rat homolog of the Drosophila enhancer of split (groucho) locus lacking WD-40 repeats.

P46439	GSTM5_HUMAN	Glutathione S-transferase Mu 5	8473333	A basis for differentiating among the multiple human Mu-glutathione S-transferases and molecular cloning of brain GSTM5.

P05067	A4_HUMAN	Amyloid beta A4 protein	19225519	APP binds DR6 to trigger axon pruning and neuron death via distinct caspases.

O14653	GOSR2_HUMAN	Golgi SNAP receptor complex member 2	9349823	A SNARE involved in protein transport through the Golgi apparatus.

Q6EBV9	ATG9B_MOUSE	Autophagy-related protein 9B	15755735	Endothelial nitric-oxide synthase antisense (NOS3AS) gene encodes an autophagy-related protein (APG9-like2) highly expressed in trophoblast.

O13971	SGD1_SCHPO	Suppressor of glycerol defect protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P50521	HXK2_SCHPO	Hexokinase-2	8549830	Schizosaccharomyces pombe possesses an unusual and a conventional hexokinase: biochemical and molecular characterization of both hexokinases.

Q86YN6	PRGC2_HUMAN	Peroxisome proliferator-activated receptor gamma coactivator 1-beta	11854298	The PGC-1-related protein PERC is a selective coactivator of estrogen receptor alpha.

Q09898	SID2_SCHPO	Serine/threonine-protein kinase sid2	15062098	Sid4p-Cdc11p assembles the septation initiation network and its regulators at the S. pombe SPB.

Q15907	RB11B_HUMAN	Ras-related protein Rab-11B	7811277	Molecular cloning of two small GTP-binding proteins from human skeletal muscle.

P92189	STIL_DROME	Protein stand still	10101125	The Drosophila gene stand still encodes a germline chromatin- associated protein that controls the transcription of the ovarian tumor gene.

O54695	SPTC1_CRIGR	Serine palmitoyltransferase 1	9405408	A mammalian homolog of the yeast LCB1 encodes a component of serine palmitoyltransferase, the enzyme catalyzing the first step in sphingolipid synthesis.

P40351	ALG8_YEAST	Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase	8016100	New phenotype of mutations deficient in glucosylation of the lipid- linked oligosaccharide: cloning of the ALG8 locus.

Q9SZT9	GH32_ARATH	Indole-3-acetic acid-amido synthetase GH3.2	15659623	Characterization of an Arabidopsis enzyme family that conjugates amino acids to indole-3-acetic acid.

P29558	RBMS1_HUMAN	RNA-binding motif, single-stranded-interacting protein 1	8041632	SCR: novel human suppresors of cdc2/cdc13 mutants of Schizosaccharomyces pombe harbour motifs for RNA binding proteins.

P92965	RSP40_ARATH	Arginine/serine-rich-splicing factor RSP40	16807317	Phosphoproteomics reveals extensive in vivo phosphorylation of Arabidopsis proteins involved in RNA metabolism.

Q66JF8	OSR1_XENTR	Protein odd-skipped-related 1	17011543	Odd-skipped genes encode repressors that control kidney development.

P13671	CO6_HUMAN	Complement component C6	2808363	Complete primary structure and functional characterization of the sixth component of the human complement system. Identification of the C5b-binding domain in complement C6.

O13862	RDP1_SCHPO	Transcriptional activator protein rdp1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q6WV16	GALT6_DROME	N-acetylgalactosaminyltransferase 6	12829714	Functional characterization and expression analysis of members of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family from Drosophila melanogaster.

Q99638	RAD9A_HUMAN	Cell cycle checkpoint control protein RAD9A	15897895	Interaction and colocalization of Rad9/Rad1/Hus1 checkpoint complex with replication protein A in human cells.

Q15223	PVRL1_HUMAN	Poliovirus receptor-related protein 1	10932188	Mutations of PVRL1, encoding a cell-cell adhesion molecule/herpesvirus receptor, in cleft lip/palate-ectodermal dysplasia.

P20449	DBP5_YEAST	ATP-dependent RNA helicase DBP5	15619606	Physical and genetic interactions link the yeast protein Zds1p with mRNA nuclear export.

Q9NR56	MBNL1_HUMAN	Muscleblind-like protein 1	15257297	Muscleblind proteins regulate alternative splicing.

P04217	A1BG_HUMAN	Alpha-1B-glycoprotein	3458201	Amino acid sequence of human plasma alpha 1B-glycoprotein: homology to the immunoglobulin supergene family.

P12525	MYCL2_HUMAN	Protein L-Myc-2	2541066	Mapping and characterization of an X-linked processed gene related to MYCL1.

Q969Q1	TRI63_HUMAN	E3 ubiquitin-protein ligase TRIM63	11243782	Identification of muscle specific ring finger proteins as potential regulators of the titin kinase domain.

Q09566	LON1_CAEEL	Protein lon-1	12051826	lon-1 regulates Caenorhabditis elegans body size downstream of the dbl-1 TGF beta signaling pathway.

Q12888	TP53B_HUMAN	Tumor suppressor p53-binding protein 1	12607005	MDC1 is a mediator of the mammalian DNA damage checkpoint.

P0ABF1	PCNB_ECOLI	Poly(A) polymerase	10361280	Poly(A) polymerase I of Escherichia coli: characterization of the catalytic domain, an RNA binding site and regions for the interaction with proteins involved in mRNA degradation.

Q8IQ72	GR65A_DROME	Putative chemosensory receptor 65a	10710312	Candidate taste receptors in Drosophila.

Q9R1Z8	VINEX_MOUSE	Vinexin	9885244	Vinexin: a novel vinculin-binding protein with multiple SH3 domains enhances actin cytoskeletal organization.

Q5PP26	PII2_ARATH	Piriformospora indica-insensitive protein 2	17397506	A leucine-rich repeat protein is required for growth promotion and enhanced seed production mediated by the endophytic fungus Piriformospora indica in Arabidopsis thaliana.

P22001	KCNA3_HUMAN	Potassium voltage-gated channel subfamily A member 3	1986382	Sequence and functional expression in Xenopus oocytes of a human insulinoma and islet potassium channel.

P04264	K2C1_HUMAN	Keratin, type II cytoskeletal 1	1381288	A leucine-->proline mutation in the H1 subdomain of keratin 1 causes epidermolytic hyperkeratosis.

Q7YU81	CHN_DROME	Protein charlatan	15703278	Charlatan, a Zn-finger transcription factor, establishes a novel level of regulation of the proneural achaete/scute genes of Drosophila.

P68510	1433F_MOUSE	14-3-3 protein eta	9738002	Association of the TLX-2 homeodomain and 14-3-3eta signaling proteins.

P47096	3HAO_YEAST	3-hydroxyanthranilate 3,4-dioxygenase	9539135	The yeast gene YJR025c encodes a 3-hydroxyanthranilic acid dioxygenase and is involved in nicotinic acid biosynthesis.

P38285	AMN1_YEAST	Antagonist of mitotic exit network protein 1	12628189	Exit from exit: resetting the cell cycle through Amn1 inhibition of G protein signaling.

P36560	ASR_ECOLI	Acid shock protein	10094685	The acid-inducible asr gene in Escherichia coli: transcriptional control by the phoBR operon.

Q8BUZ1	ABRA_MOUSE	Actin-binding Rho-activating protein	15798203	Muscle-specific signaling mechanism that links actin dynamics to serum response factor.

Q8TB24	RIN3_HUMAN	Ras and Rab interactor 3	11733506	A novel binding protein composed of homophilic tetramer exhibits unique properties for the small GTPase Rab5.

P46782	RS5_HUMAN	40S ribosomal protein S5	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

P11620	YPT1_SCHPO	GTP-binding protein ypt1	2328721	Identification of ras-related, YPT family genes in Schizosaccharomyces pombe.

P41003	SMC2_SCHPO	Structural maintenance of chromosomes protein 2	10485849	Fission yeast condensin complex: essential roles of non-SMC subunits for condensation and Cdc2 phosphorylation of Cut3/SMC4.

Q91V33	KHDR1_RAT	KH domain-containing, RNA-binding, signal transduction-associated protein 1	10437794	p68 Sam is a substrate of the insulin receptor and associates with the SH2 domains of p85 PI3K.

Q9Z2D8	MBD3_MOUSE	Methyl-CpG-binding domain protein 3	9774669	Identification and characterization of a family of mammalian methyl- CpG binding proteins.

Q7Y1I7	DNM1A_ORYSJ	DNA (cytosine-5)-methyltransferase 1A	14513380	Characterization of two rice DNA methyltransferase genes and RNAi- mediated reactivation of a silenced transgene in rice callus.

Q670P5	WNT11_XENLA	Protein Wnt-11	19582868	Xenopus Wnt11b is identified as a potential pronephric inducer.

Q99N20	BRMS1_MOUSE	Breast cancer metastasis-suppressor 1 homolog	11774238	Identification and characterization of the murine ortholog (brms1) of breast-cancer metastasis suppressor 1 (BRMS1).

O42912	TAD1_SCHPO	tRNA-specific adenosine deaminase 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O00230	CORT_HUMAN	Cortistatin	9125122	Identification and characterization of a novel human cortistatin-like peptide.

Q04458	HFD1_YEAST	Putative fatty aldehyde dehydrogenase HFD1	16407407	Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins.

Q9VTU3	RG68F_DROME	Rho GTPase-activating protein 68F	16609869	Drosophila RhoGAP68F is a putative GTPase activating protein for RhoA participating in gastrulation.

P47196	AKT1_RAT	RAC-alpha serine/threonine-protein kinase	10400692	Requirement for Akt (protein kinase B) in insulin-induced activation of glycogen synthase and phosphorylation of 4E-BP1 (PHAS-1).

Q9W157	BRCA2_DROME	Breast cancer type 2 susceptibility protein homolog	18266476	Drosophila brca2 is required for mitotic and meiotic DNA repair and efficient activation of the meiotic recombination checkpoint.

Q9NYQ3	HAOX2_HUMAN	Hydroxyacid oxidase 2	10777549	Identification and characterization of HAOX1, HAOX2, and HAOX3, three human peroxisomal 2-hydroxy acid oxidases.

Q9UTB8	INI1_SCHPO	Pre-mRNA-splicing factor ini1	14762117	A novel RING-finger-like protein Ini1 is essential for cell cycle progression in fission yeast.

Q8C1Q4	METRN_MOUSE	Meteorin	15085178	Meteorin: a secreted protein that regulates glial cell differentiation and promotes axonal extension.

Q8IVG9	HUNIN_HUMAN	Humanin	14561895	Interaction between the Alzheimer's survival peptide humanin and insulin-like growth factor-binding protein 3 regulates cell survival and apoptosis.

O74839	YC1B_SCHPO	Uncharacterized mscS family protein C1183.11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9USX3	RAD60_SCHPO	DNA repair protein rad60	11971984	The Schizosaccharomyces pombe rad60 gene is essential for repairing double-strand DNA breaks spontaneously occurring during replication and induced by DNA damaging agents.

P00812	ARGI_YEAST	Arginase	1939179	Roles of metal ions in the maintenance of the tertiary and quaternary structure of arginase from Saccharomyces cerevisiae.

Q9RC23	MRSD_BACSY	Mersacidin decarboxylase	11844751	The flavoprotein MrsD catalyzes the oxidative decarboxylation reaction involved in formation of the peptidoglycan biosynthesis inhibitor mersacidin.

Q2TV84	TRPM1_MOUSE	Transient receptor potential cation channel subfamily M member 1	19861548	TRPM1 is required for the depolarizing light response in retinal ON- bipolar cells.

P49207	RL34_HUMAN	60S ribosomal protein L34	7490091	Generation of a transcription map at the HSD17B locus centromeric to BRCA1 at 17q21.

P19334	TRP_DROME	Transient receptor potential protein	10995445	TRP and the PDZ protein, INAD, form the core complex required for retention of the signalplex in Drosophila photoreceptor cells.

O14810	CPLX1_HUMAN	Complexin-1	7553862	Complexins: cytosolic proteins that regulate SNAP receptor function.

Q01118	SCN7A_HUMAN	Sodium channel protein type 7 subunit alpha	1317577	Molecular cloning of an atypical voltage-gated sodium channel expressed in human heart and uterus: evidence for a distinct gene family.

P55072	TERA_HUMAN	Transitional endoplasmic reticulum ATPase	15215856	A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol.

Q63028	ADDA_RAT	Alpha-adducin	8543181	Characterisation and chromosomal localisation of the rat alpha- and beta-adducin-encoding genes.

Q60714	S27A1_MOUSE	Long-chain fatty acid transport protein 1	9671728	A family of fatty acid transporters conserved from mycobacterium to man.

Q9Y3B8	ORN_HUMAN	Oligoribonuclease, mitochondrial	10851236	The human homolog of Escherichia coli Orn degrades small single- stranded RNA and DNA oligomers.

P32479	HIR1_YEAST	Protein HIR1	16449659	Evidence that Spt2/Sin1, an HMG-like factor, plays roles in transcription elongation, chromatin structure, and genome stability in Saccharomyces cerevisiae.

A5GZW8	DHSD_PIG	Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial	15989954	Crystal structure of mitochondrial respiratory membrane protein complex II.

Q6PGN9	PSRC1_HUMAN	Proline/serine-rich coiled-coil protein 1	18411309	DDA3 recruits microtubule depolymerase Kif2a to spindle poles and controls spindle dynamics and mitotic chromosome movement.

P05067	A4_HUMAN	Amyloid beta A4 protein	9338779	An intracellular protein that binds amyloid-beta peptide and mediates neurotoxicity in Alzheimer's disease.

P60932	UPPP_ECOLI	Undecaprenyl-diphosphatase	8389741	Amplification of the bacA gene confers bacitracin resistance to Escherichia coli.

Q9URZ1	PIMT_SCHPO	Probable protein-L-isoaspartate O-methyltransferase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P00350	6PGD_ECOLI	6-phosphogluconate dehydrogenase, decarboxylating	19686854	Conformational changes associated with cofactor/substrate binding of 6-phosphogluconate dehydrogenase from Escherichia coli and Klebsiella pneumoniae: Implications for enzyme mechanism.

Q99788	CML1_HUMAN	Chemokine-like receptor 1	9603476	ChemR23, a putative chemoattractant receptor, is expressed in monocyte-derived dendritic cells and macrophages and is a coreceptor for SIV and some primary HIV-1 strains.

P15919	RAG1_MOUSE	V(D)J recombination-activating protein 1	14671314	Autoubiquitylation of the V(D)J recombinase protein RAG1.

P12004	PCNA_HUMAN	Proliferating cell nuclear antigen	2565339	Structure of the human gene for the proliferating cell nuclear antigen.

P97459	NPAS1_MOUSE	Neuronal PAS domain-containing protein 1	15635607	Novel function of neuronal PAS domain protein 1 in erythropoietin expression in neuronal cells.

Q99LI8	HGS_MOUSE	Hepatocyte growth factor-regulated tyrosine kinase substrate	7565774	Growth factor-induced tyrosine phosphorylation of Hrs, a novel 115- kilodalton protein with a structurally-conserved putative zinc finger domain.

Q06494	PLR1_YEAST	Putative pyridoxal reductase	14562095	Global analysis of protein localization in budding yeast.

O65036	C3H54_ARATH	Zinc finger CCCH domain-containing protein 54	9501112	PEI1, an embryo-specific zinc finger protein gene required for heart- stage embryo formation in Arabidopsis.

O94564	YGD6_SCHPO	Zinc-type alcohol dehydrogenase-like protein C1773.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P00367	DHE3_HUMAN	Glutamate dehydrogenase 1, mitochondrial	11903050	Expression, purification and characterization of human glutamate dehydrogenase (GDH) allosteric regulatory mutations.

O65351	SUBL_ARATH	Subtilisin-like protease	12413398	Ara12 subtilisin-like protease from Arabidopsis thaliana: purification, substrate specificity and tissue localization.

P15389	SCN5A_RAT	Sodium channel protein type 5 subunit alpha	2554302	Molecular cloning of a putative tetrodotoxin-resistant rat heart Na+ channel isoform.

Q12482	AGC1_YEAST	Mitochondrial aspartate-glutamate transporter AGC1	14622413	Identification and metabolic role of the mitochondrial aspartate- glutamate transporter in Saccharomyces cerevisiae.

P07197	NFM_HUMAN	Neurofilament medium polypeptide	3608989	The human mid-size neurofilament subunit: a repeated protein sequence and the relationship of its gene to the intermediate filament gene family.

Q794F9	4F2_RAT	4F2 cell-surface antigen heavy chain	9726963	Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98).

P53201	SWC4_YEAST	SWR1-complex protein 4	15485911	The Yaf9 component of the SWR1 and NuA4 complexes is required for proper gene expression, histone H4 acetylation, and Htz1 replacement near telomeres.

O15503	INSI1_HUMAN	Insulin-induced gene 1 protein	12202038	Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER.

P53334	SCW4_YEAST	Probable family 17 glucosidase SCW4	9748433	New potential cell wall glucanases of Saccharomyces cerevisiae and their involvement in mating.

P62826	RAN_HUMAN	GTP-binding nuclear protein Ran	9837918	The specificity of the CRM1-Rev nuclear export signal interaction is mediated by RanGTP.

Q96RL1	UIMC1_HUMAN	BRCA1-A complex subunit RAP80	17643121	CCDC98 targets BRCA1 to DNA damage sites.

P26391	RMLB_SALTY	dTDP-glucose 4,6-dehydratase	11796113	Toward a structural understanding of the dehydratase mechanism.

Q4U0Y4	NPL1A_XENLA	Nucleosome assembly protein 1-like 1-A	15928086	Nucleosome assembly protein-1 is a linker histone chaperone in Xenopus eggs.

P10912	GHR_HUMAN	Growth hormone receptor	8137822	A single amino acid substitution in the exoplasmic domain of the human growth hormone (GH) receptor confers familial GH resistance (Laron syndrome) with positive GH-binding activity by abolishing receptor homodimerization.

O95989	NUDT3_HUMAN	Diphosphoinositol polyphosphate phosphohydrolase 1	19585659	Crystal structure of human diphosphoinositol phosphatase 1.

O42659	APC14_SCHPO	Anaphase-promoting complex subunit 14	12786945	Overlapping omt1+ and omt2+ genes are required for spore wall maturation in Schizosaccharomyces pombe.

Q9ZWM9	RAV1_ARATH	AP2/ERF and B3 domain-containing transcription factor RAV1	15548737	Solution structure of the B3 DNA binding domain of the Arabidopsis cold-responsive transcription factor RAV1.

Q8K4H1	AFMID_MOUSE	Probable arylformamidase	12411446	Alternate activation of two divergently transcribed mouse genes from a bidirectional promoter is linked to changes in histone modification.

O13838	NUP40_SCHPO	Nucleoporin nup40	15116432	Identification of genes encoding putative nucleoporins and transport factors in the fission yeast Schizosaccharomyces pombe: a deletion analysis.

Q9P370	BUD20_SCHPO	Zinc finger protein bud20	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NV88	INT9_HUMAN	Integrator complex subunit 9	16239144	Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.

P22682	CBL_MOUSE	E3 ubiquitin-protein ligase CBL	9447983	A novel, multifunctional c-Cbl binding protein in insulin receptor signaling in 3T3-L1 adipocytes.

P79051	RHP16_SCHPO	ATP-dependent helicase rhp16	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12507	SFG1_YEAST	Superficial pseudohyphal growth protein 1	14562095	Global analysis of protein localization in budding yeast.

Q9YGK8	IRX1A_XENLA	Iroquois-class homeodomain protein irx-1-A	15242793	Role of BMP signaling and the homeoprotein Iroquois in the specification of the cranial placodal field.

Q96RT8	GCP5_HUMAN	Gamma-tubulin complex component 5	11694571	GCP5 and GCP6: two new members of the human gamma-tubulin complex.

Q96WV9	CDK9_SCHPO	Serine/threonine-protein kinase cdk9	12475973	Interactions between fission yeast Cdk9, its cyclin partner Pch1, and mRNA capping enzyme Pct1 suggest an elongation checkpoint for mRNA quality control.

P86099	NXL5_MICSU	Long neurotoxin MS5	18384102	Proteomic analysis of the venom from the fish eating coral snake Micrurus surinamensis: novel toxins, their function and phylogeny.

P47040	BTN1_YEAST	Protein BTN1	10319861	Action of BTN1, the yeast orthologue of the gene mutated in Batten disease.

Q9NZW4	DSPP_HUMAN	Dentin sialophosphoprotein	9879917	Human dentin phosphophoryn nucleotide and amino acid sequence.

P42818	KPK1_ARATH	Serine/threonine-protein kinase AtPK1/AtPK6	8021267	Atpk1, a novel ribosomal protein kinase gene from Arabidopsis. II. Functional and biochemical analysis of the encoded protein.

O15496	PA2GX_HUMAN	Group 10 secretory phospholipase A2	9188469	Cloning, chromosomal mapping, and expression of a novel human secretory phospholipase A2.

Q42605	GALE1_ARATH	UDP-glucose 4-epimerase 1	8615692	Functional expression of uridine 5'-diphospho-glucose 4-epimerase (EC 5.1.3.2) from Arabidopsis thaliana in Saccharomyces cerevisiae and Escherichia coli.

P48015	GCST_YEAST	Aminomethyltransferase, mitochondrial	9047339	Cloning, and molecular characterization of the GCV1 gene encoding the glycine cleavage T-protein from Saccharomyces cerevisiae.

Q86UL8	MAGI2_HUMAN	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2	10760291	Evidence for regulation of the PTEN tumor suppressor by a membrane- localized multi-PDZ domain containing scaffold protein MAGI-2.

Q09553	GAS1_CAEEL	Growth arrest-specific protein 1 homolog	11955608	Cloning and characterization of the C. elegans gas1 homolog: phas- 1.

Q60974	NCOR1_MOUSE	Nuclear receptor corepressor 1	7760852	Isolation of proteins that interact specifically with the retinoid X receptor: two novel orphan receptors.

Q9EPT8	CLIC5_RAT	Chloride intracellular channel protein 5	17021174	The chloride intracellular channel protein CLIC5 is expressed at high levels in hair cell stereocilia and is essential for normal inner ear function.

P32600	TOR2_YEAST	Serine/threonine-protein kinase TOR2	10329624	Tor proteins and protein phosphatase 2A reciprocally regulate Tap42 in controlling cell growth in yeast.

Q60631	GRB2_MOUSE	Growth factor receptor-bound protein 2	7689150	Molecular cloning of the mouse grb2 gene: differential interaction of the Grb2 adaptor protein with epidermal growth factor and nerve growth factor receptors.

Q16820	MEP1B_HUMAN	Meprin A subunit beta	9288916	Polarised expression of human intestinal N-benzoyl-L-tyrosyl-p- aminobenzoic acid hydrolase (human meprin) alpha and beta subunits in Madin-Darby canine kidney cells.

Q63269	ITPR3_RAT	Inositol 1,4,5-trisphosphate receptor type 3	8388391	Sequence and functional characterization of a third inositol trisphosphate receptor subtype, IP3R-3, expressed in pancreatic islets, kidney, gastrointestinal tract, and other tissues.

Q7KYR7	BT2A1_HUMAN	Butyrophilin subfamily 2 member A1	9382921	Cloning, localization, and structure of new members of the butyrophilin gene family in the juxta-telomeric region of the major histocompatibility complex.

Q9SJN0	ABI5_ARATH	Protein ABSCISIC ACID-INSENSITIVE 5	17194765	KEEP ON GOING, a RING E3 ligase essential for Arabidopsis growth and development, is involved in abscisic acid signaling.

Q9WTW1	GRIP2_RAT	Glutamate receptor-interacting protein 2	10414981	Association of AMPA receptors with a subset of glutamate receptor- interacting protein in vivo.

Q5IBH7	SPDYA_MOUSE	Speedy protein A	15611625	Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins.

Q06708	VAC14_YEAST	Vacuole morphology and inheritance protein 14	11889142	Osmotic stress-induced increase of phosphatidylinositol 3,5- bisphosphate requires Vac14p, an activator of the lipid kinase Fab1p.

Q8LC53	EPF2_ARATH	Protein EPIDERMAL PATTERNING FACTOR 2	19398336	The signaling peptide EPF2 controls asymmetric cell divisions during stomatal development.

P0C5E4	PTPRQ_MOUSE	Phosphotidylinositol phosphatase PTPRQ	14534255	A receptor-like inositol lipid phosphatase is required for the maturation of developing cochlear hair bundles.

Q9WTP9	VAX2_MOUSE	Ventral anterior homeobox 2	10595508	Misexpression of the Emx-related homeobox genes cVax and mVax2 ventralizes the retina and perturbs the retinotectal map.

P01112	RASH_HUMAN	GTPase HRas	11022048	Regulation of a novel human phospholipase C, PLCepsilon, through membrane targeting by Ras.

P11717	MPRI_HUMAN	Cation-independent mannose-6-phosphate receptor	10900005	Internalization of CD26 by mannose 6-phosphate/insulin-like growth factor II receptr contributes to T cell activation.

Q92673	SORL_HUMAN	Sortilin-related receptor	9157966	A novel mosaic protein containing LDL receptor elements is highly conserved in humans and chickens.

Q62187	TTF1_MOUSE	Transcription termination factor 1	9049305	RNA polymerase I transcription on nucleosomal templates: the transcription termination factor TTF-I induces chromatin remodeling and relieves transcriptional repression.

Q93088	BHMT1_HUMAN	Betaine--homocysteine S-methyltransferase 1	10075673	Interaction between dietary methionine and methyl donor intake on rat liver betaine-homocysteine methyltransferase gene expression and organization of the human gene.

Q9V730	EXT1_DROME	Exostosin-1	16303756	Heparan sulfate polymerization in Drosophila.

P13609	SRGN_MOUSE	Serglycin	16807245	Serglycin is the major secreted proteoglycan in macrophages and has a role in the regulation of macrophage tumor necrosis factor-alpha secretion in response to lipopolysaccharide.

Q96L91	EP400_HUMAN	E1A-binding protein p400	14966270	Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans.

Q5EAF2	IP5PB_ARATH	Type I inositol-1,4,5-trisphosphate 5-phosphatase 11	15181205	Molecular characterization of an Arabidopsis gene encoding a phospholipid-specific inositol polyphosphate 5-phosphatase.

Q15208	STK38_HUMAN	Serine/threonine-protein kinase 38	12493777	Mechanism of Ca2+-mediated regulation of NDR protein kinase through autophosphorylation and phosphorylation by an upstream kinase.

Q7KRY6	NHK1_DROME	Nucleosomal histone kinase 1	15078818	Nucleosomal histone kinase-1 phosphorylates H2A Thr 119 during mitosis in the early Drosophila embryo.

Q8JGW0	TSP4B_DANRE	Thrombospondin-4-B	12592708	The zebrafish thrombospondin 3 and 4 genes (thbs3 and thbs4): cDNA and protein structure.

Q5W7F2	AGD3_ARATH	ADP-ribosylation factor GTPase-activating protein AGD3	15923323	DRP1A is responsible for vascular continuity synergistically working with VAN3 in Arabidopsis.

P41996	CPG2_CAEEL	Chondroitin proteoglycan-2	11562350	Identification of in vivo mRNA targets of GLD-1, a maxi-KH motif containing protein required for C. elegans germ cell development.

Q6Q788	APOA5_HUMAN	Apolipoprotein A-V	15528295	The novel apolipoprotein A5 is present in human serum, is associated with VLDL, HDL, and chylomicrons, and circulates at very low concentrations compared with other apolipoproteins.

Q9VVI3	NEDD4_DROME	E3 ubiquitin-protein ligase Nedd-4	12165468	Drosophila Nedd4, a ubiquitin ligase, is recruited by Commissureless to control cell surface levels of the roundabout receptor.

P54678	ATC1_DICDI	Calcium-transporting ATPase PAT1	9885293	Involvement of the Ca2+-ATPase PAT1 and the contractile vacuole in calcium regulation in Dictyostelium discoideum.

Q54DD0	AMPD_DICDI	AMP deaminase	11784104	Altered cell-type proportioning in Dictyostelium lacking adenosine monophosphate deaminase.

Q9NS23	RASF1_HUMAN	Ras association domain-containing protein 1	15109305	Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras.

Q9Y5E6	PCDB3_HUMAN	Protocadherin beta-3	10380929	A striking organization of a large family of human neural cadherin- like cell adhesion genes.

O14085	SEC72_SCHPO	Translocation protein sec72	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Z0J5	TRXR2_RAT	Thioredoxin reductase 2, mitochondrial	9988709	Molecular cloning and characterization of a mitochondrial selenocysteine-containing thioredoxin reductase from rat liver.

Q9P212	PLCE1_HUMAN	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon-1	11022048	Regulation of a novel human phospholipase C, PLCepsilon, through membrane targeting by Ras.

Q12449	AHA1_YEAST	Hsp90 co-chaperone AHA1	12604615	Aha1 binds to the middle domain of Hsp90, contributes to client protein activation, and stimulates the ATPase activity of the molecular chaperone.

P09916	SLIB_RAT	Somatoliberin	1924334	Expression of the rat growth hormone-releasing hormone gene in placenta is directed by an alternative promoter.

P55000	SLUR1_HUMAN	Secreted Ly-6/uPAR-related protein 1	14721776	ARS component B: structural characterization, tissue expression and regulation of the gene and protein (SLURP-1) associated with Mal de Meleda.

Q9LYQ8	CIPK2_ARATH	CBL-interacting serine/threonine-protein kinase 2	11230129	The NAF domain defines a novel protein-protein interaction module conserved in Ca(2+)-regulated kinases.

Q01064	PDE1B_HUMAN	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	8855339	Inhibition of calmodulin-dependent phosphodiesterase induces apoptosis in human leukemic cells.

Q9LZY0	MA654_ARATH	65-kDa microtubule-associated protein 4	15469496	Molecular dissection of plant cytokinesis and phragmoplast structure: a survey of GFP-tagged proteins.

B7ZS96	TTHY_XENLA	Transthyretin	16627555	In vitro and in vivo analysis of the thyroid system-disrupting activities of brominated phenolic and phenol compounds in Xenopus laevis.

Q91YE5	BAZ2A_MOUSE	Bromodomain adjacent to zinc finger domain protein 2A	18600236	The structure of NoRC-associated RNA is crucial for targeting the chromatin remodelling complex NoRC to the nucleolus.

Q8WUM0	NU133_HUMAN	Nuclear pore complex protein Nup133	11684705	Novel vertebrate nucleoporins Nup133 and Nup160 play a role in mRNA export.

Q06137	YL345_YEAST	Putative 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase YLR345W	14562095	Global analysis of protein localization in budding yeast.

P51160	PDE6C_HUMAN	Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	8641425	Human cone-specific cGMP phosphodiesterase alpha' subunit: complete cDNA sequence and gene arrangement.

P43601	ATG18_YEAST	Autophagy-related protein 18	11707261	Autophagy and the cytoplasm to vacuole targeting pathway both require Aut10p.

P19835	CEL_HUMAN	Bile salt-activated lipase	7578248	Bile salt-dependent lipase transcripts in human fetal tissues.

Q9HAU4	SMUF2_HUMAN	E3 ubiquitin-protein ligase SMURF2	17719543	Autoinhibition of the HECT-type ubiquitin ligase Smurf2 through its C2 domain.

Q99216	PNO1_YEAST	Pre-rRNA-processing protein PNO1	12502737	Nob1p is required for biogenesis of the 26S proteasome and degraded upon its maturation in Saccharomyces cerevisiae.

O14756	H17B6_HUMAN	17-beta-hydroxysteroid dehydrogenase type 6	9188497	Expression cloning and characterization of oxidative 17beta- and 3alpha-hydroxysteroid dehydrogenases from rat and human prostate.

P35999	PMIP_YEAST	Mitochondrial intermediate peptidase	8035833	MIP1, a new yeast gene homologous to the rat mitochondrial intermediate peptidase gene, is required for oxidative metabolism in Saccharomyces cerevisiae.

P17028	ZNF24_HUMAN	Zinc finger protein 24	2288909	Multiple genes encoding zinc finger domains are expressed in human T cells.

P38398	BRCA1_HUMAN	Breast cancer type 1 susceptibility protein	12890688	The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitin.

Q17390	CUL2_CAEEL	Cullin-2	17609115	A CUL-2 ubiquitin ligase containing three FEM proteins degrades TRA-1 to regulate C. elegans sex determination.

Q75JI3	NSF_DICDI	Vesicle-fusing ATPase	17606987	Possible roles of the endocytic cycle in cell motility.

O95926	SYF2_HUMAN	Pre-mRNA-splicing factor SYF2	11118353	p29, a novel GCIP-interacting protein, localizes in the nucleus.

Q8BP74	PSTK_MOUSE	L-seryl-tRNA(Sec) kinase	15317934	Identification and characterization of phosphoseryl-tRNA[Ser]Sec kinase.

Q27355	LIN26_CAEEL	Transcription factor lin-26	7956818	The Caenorhabditis elegans gene lin-26 is required to specify the fates of hypodermal cells and encodes a presumptive zinc-finger transcription factor.

Q27365	LI15A_CAEEL	Protein lin-15A	8054684	The lin-15 locus encodes two negative regulators of Caenorhabditis elegans vulval development.

P54775	PRS6B_MOUSE	26S protease regulatory subunit 6B	10945464	Mouse proteasomal ATPases Psmc3 and Psmc4: genomic organization and gene targeting.

Q9P6I0	SYNM_SCHPO	Asparaginyl-tRNA synthetase, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P21574	YBX2A_XENLA	Y-box-binding protein 2-A	2247479	Xenopus Y-box transcription factors: molecular cloning, functional analysis and developmental regulation.

Q9JKN1	ZNT7_MOUSE	Zinc transporter 7	12446736	ZnT7, a novel mammalian zinc transporter, accumulates zinc in the Golgi apparatus.

Q9PTH3	IBP2A_DANRE	Insulin-like growth factor-binding protein 2-A	19081843	Duplication of the IGFBP-2 gene in teleost fish: protein structure and functionality conservation and gene expression divergence.

O14026	SET2_SCHPO	Histone-lysine N-methyltransferase, H3 lysine-36 specific	16087749	Histone H3 K36 methylation is associated with transcription elongation in Schizosaccharomyces pombe.

O55143	AT2A2_MOUSE	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	14749390	TRAM2 protein interacts with endoplasmic reticulum Ca2+ pump Serca2b and is necessary for collagen type I synthesis.

P04114	APOB_HUMAN	Apolipoprotein B-100	2563166	Association between a specific apolipoprotein B mutation and familial defective apolipoprotein B-100.

Q39123	ATHB8_ARATH	Homeobox-leucine zipper protein ATHB-8	8575317	The expression of the Athb-8 homeobox gene is restricted to provascular cells in Arabidopsis thaliana.

Q15018	F175B_HUMAN	BRISC complex subunit Abro1	19261749	NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control.

P50539	MXI1_HUMAN	Max-interacting protein 1	8425219	Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites.

Q9CQ39	MED21_MOUSE	Mediator of RNA polymerase II transcription subunit 21	10500093	Ubiquitous expression and embryonic requirement for RNA polymerase II coactivator subunit Srb7 in mice.

Q9Z260	CLD8_MOUSE	Claudin-8	9892664	Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands.

Q9VEX9	SAP18_DROME	Histone deacetylase complex subunit SAP18	11455422	Drosophila SAP18, a member of the Sin3/Rpd3 histone deacetylase complex, interacts with Bicoid and inhibits its activity.

P40553	DOT5_YEAST	Peroxiredoxin DOT5	10681558	Distinct physiological functions of thiol peroxidase isoenzymes in Saccharomyces cerevisiae.

P36159	RNZ_YEAST	Ribonuclease Z	14562095	Global analysis of protein localization in budding yeast.

P32787	MG101_YEAST	Mitochondrial genome maintenance protein MGM101	10209025	Mgm101p is a novel component of the mitochondrial nucleoid that binds DNA and is required for the repair of oxidatively damaged mitochondrial DNA.

Q62737	CY24A_RAT	Cytochrome b-245 light chain	10938010	Molecular characterization and localization of the NAD(P)H oxidase components gp91-phox and p22-phox in endothelial cells.

Q9LN68	GATL1_ARATH	Probable galacturonosyltransferase-like 1	17991630	The PARVUS gene is expressed in cells undergoing secondary wall thickening and is essential for glucuronoxylan biosynthesis.

Q9C0Y7	YKM7_SCHPO	Uncharacterized protein PB24D3.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q03327	UGO1_YEAST	Mitochondrial fusion and transport protein UGO1	12808034	Mgm1p, a dynamin-related GTPase, is essential for fusion of the mitochondrial outer membrane.

Q8K3K8	OPTN_MOUSE	Optineurin	15607428	Molecular cloning, genomic structure, and protein characterization of mouse optineurin.

Q940H6	SRK2E_ARATH	Serine/threonine-protein kinase SRK2E	12468729	Arabidopsis OST1 protein kinase mediates the regulation of stomatal aperture by abscisic acid and acts upstream of reactive oxygen species production.

O13772	HUA1_SCHPO	Proline/serine-rich protein C17A5.10	12529438	Global transcriptional responses of fission yeast to environmental stress.

Q93PP8	RUBR2_DESDA	Rubredoxin-2	9662435	Characterisation of a new rubredoxin isolated from Desulfovibrio desulfuricans 27774: definition of a new family of rubredoxins.

Q9UJV9	DDX41_HUMAN	Probable ATP-dependent RNA helicase DDX41	10607561	Developmental and cell biological functions of the Drosophila DEAD- box protein abstrakt.

P19332	TAU_RAT	Microtubule-associated protein tau	20133804	A role for FKBP52 in Tau protein function.

O88700	BLM_MOUSE	Bloom syndrome protein homolog	9840919	Point mutations causing Bloom's syndrome abolish ATPase and DNA helicase activities of the BLM protein.

P39939	RS26B_YEAST	40S ribosomal protein S26-B	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

P40366	DLS1_YEAST	Protein DLS1	14562095	Global analysis of protein localization in budding yeast.

P38242	ALG14_YEAST	UDP-N-acetylglucosamine transferase subunit ALG14	15282802	Localization of proteins that are coordinately expressed with Cln2 during the cell cycle.

P49674	KC1E_HUMAN	Casein kinase I isoform epsilon	7797465	Isolation and characterization of human casein kinase I epsilon (CKI), a novel member of the CKI gene family.

Q9V2V5	PSA2_HALVD	Proteasome subunit alpha 2	10482525	Halophilic 20S proteasomes of the archaeon Haloferax volcanii: purification, characterization, and gene sequence analysis.

O75190	DNJB6_HUMAN	DnaJ homolog subfamily B member 6	11896048	Characterization of a brain-enriched chaperone, MRJ, that inhibits Huntingtin aggregation and toxicity independently.

Q6P1M3	L2GL2_HUMAN	Lethal(2) giant larvae protein homolog 2	12725730	Mammalian Lgl forms a protein complex with PAR-6 and aPKC independently of PAR-3 to regulate epithelial cell polarity.

P63146	UBE2B_HUMAN	Ubiquitin-conjugating enzyme E2 B	1717990	Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6.

P10252	CD48_RAT	CD48 antigen	3181129	The MRC OX-45 antigen of rat leukocytes and endothelium is in a subset of the immunoglobulin superfamily with CD2, LFA-3 and carcinoembryonic antigens.

Q9Z2A6	MK15_RAT	Mitogen-activated protein kinase 15	11287416	ERK7 is an autoactivated member of the MAPK family.

P35735	SFK1_YEAST	Protein SFK1	12015967	Stt4 PI 4-kinase localizes to the plasma membrane and functions in the Pkc1-mediated MAP kinase cascade.

O65479	CRK20_ARATH	Putative cysteine-rich receptor-like protein kinase 20	15604743	Activation of hypersensitive cell death by pathogen-induced receptor- like protein kinases from Arabidopsis.

Q8LCE1	GLN12_ARATH	Glutamine synthetase cytosolic isozyme 1-2	10482686	Carbon and amino acids reciprocally modulate the expression of glutamine synthetase in Arabidopsis.

O97936	MSPA_SAGOE	Beta-microseminoprotein A1	10491085	New world, but not old world, monkeys carry several genes encoding beta-microseminoprotein.

Q04673	SSL1_YEAST	Suppressor of stem-loop protein 1	14500720	Revised subunit structure of yeast transcription factor IIH (TFIIH) and reconciliation with human TFIIH.

Q6KC79	NIPBL_HUMAN	Nipped-B-like protein	15882967	The mammalian heterochromatin protein 1 binds diverse nuclear proteins through a common motif that targets the chromoshadow domain.

P32156	RHAM_ECOLI	L-rhamnose mutarotase	15876375	Structural insights into the monosaccharide specificity of Escherichia coli rhamnose mutarotase.

Q15011	HERP1_HUMAN	Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein	10922362	Herp, a new ubiquitin-like membrane protein induced by endoplasmic reticulum stress.

Q94JS4	SMT3B_ARATH	24-methylenesterol C-methyltransferase 3	9208946	Identification of cDNAs encoding sterol methyl-transferases involved in the second methylation step of plant sterol biosynthesis.

P37806	UNC87_CAEEL	Protein unc-87	7929573	The Caenorhabditis elegans muscle-affecting gene unc-87 encodes a novel thin filament-associated protein.

Q8TD84	DSCL1_HUMAN	Down syndrome cell adhesion molecule-like protein 1	12051741	Mammalian DSCAMs: roles in the development of the spinal cord, cortex, and cerebellum?

P01602	KV110_HUMAN	Ig kappa chain V-I region HK102	6779204	Human immunoglobulin variable region genes -- DNA sequences of two V kappa genes and a pseudogene.

Q01475	SAR1_SCHPO	Small COPII coat GTPase sar1	1396601	Fission yeast and a plant have functional homologues of the Sar1 and Sec12 proteins involved in ER to Golgi traffic in budding yeast.

O35615	FOG1_MOUSE	Zinc finger protein ZFPM1	14614148	Endothelial lineage-mediated loss of the GATA cofactor Friend of GATA 1 impairs cardiac development.

P79832	ARNT_ONCMY	Aryl hydrocarbon receptor nuclear translocator	11230806	Functional analysis of activation and repression domains of the rainbow trout aryl hydrocarbon receptor nuclear translocator (rtARNT) protein isoforms.

P11035	NIA2_ARATH	Nitrate reductase [NADH] 2	1840922	Identification of the Arabidopsis CHL3 gene as the nitrate reductase structural gene NIA2.

P26231	CTNA1_MOUSE	Catenin alpha-1	10882138	Structure of the dimerization and beta-catenin-binding region of alpha-catenin.

O75385	ULK1_HUMAN	Serine/threonine-protein kinase ULK1	19211835	Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy.

P46601	HAT2_ARATH	Homeobox-leucine zipper protein HAT2	12492842	The HAT2 gene, a member of the HD-Zip gene family, isolated as an auxin inducible gene by DNA microarray screening, affects auxin response in Arabidopsis.

Q22708	SYM2_CAEEL	RNA-binding protein sym-2	15579686	The identities of sym-2, sym-3 and sym-4, three genes that are synthetically lethal with mec-8 in Caenorhabditis elegans.

Q9JLB4	CUBN_MOUSE	Cubilin	11856751	Cubilin, a binding partner for galectin-3 in the murine utero- placental complex.

Q9W1A4	TAMO_DROME	Protein tamozhennic	12653959	Tamo selectively modulates nuclear import in Drosophila.

Q92621	NU205_HUMAN	Nuclear pore complex protein Nup205	9348540	Nup93, a vertebrate homologue of yeast Nic96p, forms a complex with a novel 205-kDa protein and is required for correct nuclear pore assembly.

P69718	REV_HV1H3	Protein Rev	2015625	HIV-1 structural gene expression requires the binding of multiple Rev monomers to the viral RRE: implications for HIV-1 latency.

P09085	CAD_DROME	Homeotic protein caudal	2433048	Expression of the caudal gene in the germ line of Drosophila: formation of an RNA and protein gradient during early embryogenesis.

Q13231	CHIT1_HUMAN	Chitotriosidase-1	19725875	Common G102S polymorphism in chitotriosidase differentially affects activity towards 4-methylumbelliferyl substrates.

P61247	RS3A_HUMAN	40S ribosomal protein S3a	11823430	Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains.

Q9VHY5	TAF7_DROME	Transcription initiation factor TFIID subunit 7	9601978	Repetitive arrays containing a housekeeping gene promoter have altered polytene chromosome morphology in Drosophila.

Q9H2G9	GO45_HUMAN	Golgin-45	9129147	JEM-1, a novel gene encoding a leucine-zipper nuclear factor upregulated during retinoid-induced maturation of NB4 promyelocytic leukaemia.

Q7XA73	TIF4A_ARATH	Protein TIFY 4A	20360743	NINJA connects the co-repressor TOPLESS to jasmonate signalling.

P36618	CDC16_SCHPO	Cell division control protein 16	15062098	Sid4p-Cdc11p assembles the septation initiation network and its regulators at the S. pombe SPB.

P24844	MYL9_HUMAN	Myosin regulatory light polypeptide 9	2526655	Characterization and differential expression of human vascular smooth muscle myosin light chain 2 isoform in nonmuscle cells.

Q5EAK6	ATM_DROME	Serine/threonine-protein kinase ATM	15256487	Drosophila atm/telomere fusion is required for telomeric localization of HP1 and telomere position effect.

P31675	SETA_ECOLI	Sugar efflux transporter A	10438463	Functional and biochemical characterization of Escherichia coli sugar efflux transporters.

P40505	SDS3_YEAST	Transcriptional regulatory protein SDS3	16314178	Stable incorporation of sequence specific repressors Ash1 and Ume6 into the Rpd3L complex.

P97924	KALRN_RAT	Kalirin	9285789	Huntingtin-associated protein 1 (HAP1) binds to a Trio-like polypeptide, with a rac1 guanine nucleotide exchange factor domain.

P29322	EPHA8_HUMAN	Ephrin type-A receptor 8	1648701	eek and erk, new members of the eph subclass of receptor protein- tyrosine kinases.

P32375	ALN_YEAST	Allantoinase	1803816	The allantoinase (DAL1) gene of Saccharomyces cerevisiae.

O18412	FZO_DROME	Transmembrane GTPase fzo	9230308	Developmentally regulated mitochondrial fusion mediated by a conserved, novel, predicted GTPase.

Q8LE52	DHAR3_ARATH	Glutathione S-transferase DHAR3, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q02978	M2OM_HUMAN	Mitochondrial 2-oxoglutarate/malate carrier protein	1457818	Sequences of the human and bovine genes for the mitochondrial 2- oxoglutarate carrier.

P30560	V1AR_RAT	Vasopressin V1a receptor	12887422	Viral vector-mediated gene transfer of the vole V1a vasopressin receptor in the rat septum: improved social discrimination and active social behaviour.

P69856	NANC_ECOLI	Probable N-acetylneuraminic acid outer membrane channel protein nanC	15743943	Function and expression of an N-acetylneuraminic acid-inducible outer membrane channel in Escherichia coli.

Q4FZC9	SYNE3_MOUSE	Nesprin-3	18396275	Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness.

Q9UN73	PCDA6_HUMAN	Protocadherin alpha-6	10380929	A striking organization of a large family of human neural cadherin- like cell adhesion genes.

P10746	HEM4_HUMAN	Uroporphyrinogen-III synthase	3174619	Human uroporphyrinogen III synthase: molecular cloning, nucleotide sequence, and expression of a full-length cDNA.

O00358	FOXE1_HUMAN	Forkhead box protein E1	9697705	Mutation of the gene encoding human TTF-2 associated with thyroid agenesis, cleft palate and choanal atresia.

Q91904	FXI1A_XENLA	Forkhead box protein I1-A	8735935	A fork head related multigene family is transcribed in Xenopus laevis embryos.

Q96SB4	SRPK1_HUMAN	Serine/threonine-protein kinase SRPK1	8208298	A serine kinase regulates intracellular localization of splicing factors in the cell cycle.

Q39243	TRXB1_ARATH	Thioredoxin reductase 1	15642341	AtNTRB is the major mitochondrial thioredoxin reductase in Arabidopsis thaliana.

Q91Y63	S13A3_MOUSE	Solute carrier family 13 member 3	11287335	Cloning and functional characterization of a high-affinity Na(+)/dicarboxylate cotransporter from mouse brain.

Q9UNM6	PSD13_HUMAN	26S proteasome non-ATPase regulatory subunit 13	9714768	cDNA cloning and functional analysis of p28 (Nas6p) and p40.5 (Nas7p), two novel regulatory subunits of the 26S proteasome.

P35364	5HT5A_RAT	5-hydroxytryptamine receptor 5A	7682702	Two members of a distinct subfamily of 5-hydroxytryptamine receptors differentially expressed in rat brain.

Q4KWH5	PLCH1_MOUSE	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta-1	15702972	Molecular cloning and characterization of a novel phospholipase C, PLC-eta.

P53741	BRE5_YEAST	UBP3-associated protein BRE5	12778054	Ubp3 requires a cofactor, Bre5, to specifically de-ubiquitinate the COPII protein, Sec23.

Q7Z5L7	PODN_HUMAN	Podocan	15063725	Functional characterization of podocan, a member of a new class in the small leucine-rich repeat protein family.

P60709	ACTB_HUMAN	Actin, cytoplasmic 1	15328537	Emerin caps the pointed end of actin filaments: evidence for an actin cortical network at the nuclear inner membrane.

Q9NPJ6	MED4_HUMAN	Mediator of RNA polymerase II transcription subunit 4	10235267	Composite co-activator ARC mediates chromatin-directed transcriptional activation.

Q91V88	NPNT_MOUSE	Nephronectin	11470831	Identification and characterization of a novel extracellular matrix protein nephronectin that is associated with integrin alpha8beta1 in the embryonic kidney.

P50232	SYT4_RAT	Synaptotagmin-4	7892240	Synaptotagmin IV is an immediate early gene induced by depolarization in PC12 cells and in brain.

P08266	RPB2_DROME	DNA-directed RNA polymerase II subunit RPB2	3116266	RNA polymerase II of Drosophila. Relation of its 140,000 Mr subunit to the beta subunit of Escherichia coli RNA polymerase.

P53201	SWC4_YEAST	SWR1-complex protein 4	14562095	Global analysis of protein localization in budding yeast.

Q08182	YAP7_YEAST	AP-1-like transcription factor YAP7	9372930	Yap, a novel family of eight bZIP proteins in Saccharomyces cerevisiae with distinct biological functions.

P25322	CCND1_MOUSE	G1/S-specific cyclin-D1	19767775	Lysine 269 is essential for cyclin D1 ubiquitylation by the SCF(Fbx4/alphaB-crystallin) ligase and subsequent proteasome-dependent degradation.

Q4R1I4	OPN4_BRABE	Melanopsin	15936279	Cephalochordate melanopsin: evolutionary linkage between invertebrate visual cells and vertebrate photosensitive retinal ganglion cells.

P0A6K3	DEF_ECOLI	Peptide deformylase	9610360	Isolation and crystallization of functionally competent Escherichia coli peptide deformylase forms containing either iron or nickel in the active site.

Q9U7C9	NUCMR_DICDI	Nucleomorphin	11919178	Nucleomorphin. A novel, acidic, nuclear calmodulin-binding protein from Dictyostelium that regulates nuclear number.

P61326	MGN_HUMAN	Protein mago nashi homolog	10662555	MAGOH interacts with a novel RNA-binding protein.

O00634	NET3_HUMAN	Netrin-3	9143507	The NTN2L gene encoding a novel human netrin maps to the autosomal dominant polycystic kidney disease region on chromosome 16p13.3.

Q14651	PLSI_HUMAN	Plastin-1	8139549	Identification of I-plastin, a human fimbrin isoform expressed in intestine and kidney.

Q9BXT2	CCG6_HUMAN	Voltage-dependent calcium channel gamma-6 subunit	11170751	A cluster of three novel Ca(2+) channel gamma subunit genes on chromosome 19q13.4: evolution and expression profile of the gamma subunit gene family.

Q16385	SSX2_HUMAN	Protein SSX2	7539744	Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppel-associated box in human synovial sarcoma.

Q8CBD1	NRIP1_MOUSE	Nuclear receptor-interacting protein 1	9774688	Cloning and characterization of mouse RIP140, a corepressor for nuclear orphan receptor TR2.

Q9HBI0	PARVG_HUMAN	Gamma-parvin	11171322	Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily.

O74999	RAD7_SCHPO	DNA repair protein rhp7	10446227	Characterization of the rhp7(+) and rhp16(+) genes in Schizosaccharomyces pombe.

Q91848	SIAM_XENLA	Homeobox protein siamois	12710967	Molecular link in the sequential induction of the Spemann organizer: direct activation of the cerberus gene by Xlim-1, Xotx2, Mix.1, and Siamois, immediately downstream from Nodal and Wnt signaling.

O76071	CIAO1_HUMAN	Probable cytosolic iron-sulfur protein assembly protein CIAO1	9556563	Ciao 1 is a novel WD40 protein that interacts with the tumor suppressor protein WT1.

P34109	MYOD_DICDI	Myosin ID heavy chain	8325874	Sequence, expression pattern, intracellular localization, and targeted disruption of the Dictyostelium myosin ID heavy chain isoform.

O14490	DLGP1_HUMAN	Disks large-associated protein 1	9024696	GKAP, a novel synaptic protein that interacts with the guanylate kinase-like domain of the PSD-95/SAP90 family of channel clustering molecules.

P52032	GPX1_ARATH	Phospholipid hydroperoxide glutathione peroxidase 1, chloroplastic	12766230	Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.

P43553	ALR2_YEAST	Magnesium transporter ALR2	9430719	Overexpression of the Saccharomyces cerevisiae magnesium transport system confers resistance to aluminum ion.

Q3TCN2	PLBL2_MOUSE	Putative phospholipase B-like 2	17105447	Biochemical characterization and lysosomal localization of the mannose-6-phosphate protein p76 (hypothetical protein LOC196463).

P21541	ZYG11_CAEEL	Early embryogenesis protein zyg-11	15215209	CUL-2 and ZYG-11 promote meiotic anaphase II and the proper placement of the anterior-posterior axis in C. elegans.

P25632	RSC6_YEAST	Chromatin structure-remodeling complex protein RSC6	10025404	Histone octamer transfer by a chromatin-remodeling complex.

Q8JHF2	LFNG_DANRE	Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe	14518000	Lunatic fringe regulates Delta-Notch induction of hypochord in zebrafish.

O43196	MSH5_HUMAN	MutS protein homolog 5	9740671	Cloning, structural characterization, and chromosomal localization of the human orthologue of Saccharomyces cerevisiae MSH5 gene.

Q92876	KLK6_HUMAN	Kallikrein-6	11668196	The spectrum of human kallikrein 6 (zyme/protease M/neurosin) expression in human tissues as assessed by immunohistochemistry.

O14015	MU108_SCHPO	Meiotically up-regulated gene 108 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P63220	RS21_HUMAN	40S ribosomal protein S21	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

Q12901	ZN155_HUMAN	Zinc finger protein 155	7557990	Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders.

Q9C115	REC25_SCHPO	Meiotic recombination protein rec25	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

Q61080	FOXF1_MOUSE	Forkhead box protein F1	8626802	Differential activation of lung-specific genes by two forkhead proteins, FREAC-1 and FREAC-2.

O95169	NDUB8_HUMAN	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial	9878551	cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed.

P22516	CHL1_YEAST	ATP-dependent RNA helicase CHL1	10931920	CHL1 is a nuclear protein with an essential ATP binding site that exhibits a size-dependent effect on chromosome segregation.

O73798	IGF1R_XENLA	Insulin-like growth factor 1 receptor	1847619	Insulin and insulin-like-growth-factor-I (IGF-I) receptors in Xenopus laevis oocytes. Comparison with insulin receptors from liver and muscle.

P23895	EMRE_ECOLI	Multidrug transporter emrE	1320256	Cloning and characterization of the mvrC gene of Escherichia coli K- 12 which confers resistance against methyl viologen toxicity.

P0AD01	DCUR_ECOLI	Transcriptional regulatory protein dcuR	9765574	Fumarate regulation of gene expression in Escherichia coli by the DcuSR (dcuSR genes) two-component regulatory system.

Q9H1E1	RNAS7_HUMAN	Ribonuclease 7	12244054	RNase 7, a novel innate immune defense antimicrobial protein of healthy human skin.

Q9UBU9	NXF1_HUMAN	Nuclear RNA export factor 1	9175835	Tap: a novel cellular protein that interacts with tip of herpesvirus saimiri and induces lymphocyte aggregation.

P23327	SRCH_HUMAN	Sarcoplasmic reticulum histidine-rich calcium-binding protein	2037293	cDNA and genomic cloning of HRC, a human sarcoplasmic reticulum protein, and localization of the gene to human chromosome 19 and mouse chromosome 7.

Q9JIB0	MOG1_MOUSE	Ran guanine nucleotide release factor	10811801	The mammalian Mog1 protein is a guanine nucleotide release factor for Ran.

O60077	ARZ1_SCHPO	Armadillo repeat-containing zfs1 target protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O94708	YC58_SCHPO	Uncharacterized protein C1259.08	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9EPQ8	TCF20_MOUSE	Transcription factor 20	7760812	Molecular characterization of a novel transcription factor that controls stromelysin expression.

Q54F93	MPPA2_DICDI	Mitochondrial-processing peptidase subunit alpha-2	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P10912	GHR_HUMAN	Growth hormone receptor	9360546	A membrane-fixed, truncated isoform of the human growth hormone receptor.

O74750	YEA4_SCHPO	UDP-N-acetylglucosamine transporter yea4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12245	POC4_YEAST	Proteasome chaperone 4	14562095	Global analysis of protein localization in budding yeast.

Q9SL02	RAD50_ARATH	DNA repair protein RAD50	11172016	RAD50 function is essential for telomere maintenance in Arabidopsis.

Q9NRA2	S17A5_HUMAN	Sialin	10581036	A new gene, encoding an anion transporter, is mutated in sialic acid storage diseases.

P53688	HST4_YEAST	NAD-dependent histone deacetylase HST4	16815704	The sirtuins Hst3 and Hst4p preserve genome integrity by controlling histone H3 lysine 56 deacetylation.

Q9UKC9	FBXL2_HUMAN	F-box/LRR-repeat protein 2	10531037	A family of mammalian F-box proteins.

Q12802	AKP13_HUMAN	A-kinase anchor protein 13	8290273	Novel human oncogene lbc detected by transfection with distinct homology regions to signal transduction products.

Q9W701	CLCKB_XENLA	Chloride channel protein ClC-Kb	10359659	Expression and targeting to the plasma membrane of xClC-K, a chloride channel specifically expressed in distinct tubule segments of Xenopus laevis kidney.

P01123	YPT1_YEAST	GTP-binding protein YPT1	12802060	Dual prenylation is required for Rab protein localization and function.

Q8MQJ9	BRAT_DROME	Brain tumor protein	11274060	Drosophila Brain tumor is a translational repressor.

Q6IVW0	IFT57_DANRE	Intraflagellar transport protein 57 homolog	15790966	Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis.

A2A935	PRD16_MOUSE	PR domain zinc finger protein 16	18483224	Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex.

Q9NSU2	TREX1_HUMAN	Three prime repair exonuclease 1	10393201	A human DNA editing enzyme homologous to the Escherichia coli DnaQ/MutD protein.

Q7TMB3	PPR3C_MOUSE	Protein phosphatase 1 regulatory subunit 3C	9045612	PTG, a protein phosphatase 1-binding protein with a role in glycogen metabolism.

Q07845	GRC3_YEAST	Protein GRC3	12837249	A panoramic view of yeast noncoding RNA processing.

P21810	PGS1_HUMAN	Biglycan	1860845	Human biglycan gene. Putative promoter, intron-exon junctions, and chromosomal localization.

Q92900	RENT1_HUMAN	Regulator of nonsense transcripts 1	14636577	Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7.

Q9FH36	GAUTC_ARATH	Probable galacturonosyltransferase 12	17237350	The Arabidopsis irregular xylem8 mutant is deficient in glucuronoxylan and homogalacturonan, which are essential for secondary cell wall integrity.

O94955	RHBT3_HUMAN	Rho-related BTB domain-containing protein 3	19490898	RhoBTB3: a Rho GTPase-family ATPase required for endosome to Golgi transport.

Q6AYH3	RNF34_RAT	E3 ubiquitin-protein ligase RNF34	12859687	A palmitoylated RING finger ubiquitin ligase and its homologue in the brain membranes.

Q03730	YMB8_YEAST	Uncharacterized vacuolar membrane protein YML018C	14562095	Global analysis of protein localization in budding yeast.

Q9R224	BEX1_MOUSE	Protein BEX1	12911636	Identification of members of the Bex gene family as olfactory marker protein (OMP) binding partners.

Q8C9B9	DIDO1_MOUSE	Death-inducer obliterator 1	10393935	DIO-1 is a novel gene involved in onset of apoptosis in vitro, whose misexpression disrupts limb development.

P36041	EAP1_YEAST	Protein EAP1	16120600	GYF domain proteomics reveals interaction sites in known and novel target proteins.

Q99109	REP1_USTMA	Repellent protein 1	8861956	A novel class of small amphipathic peptides affect aerial hyphal growth and surface hydrophobicity in Ustilago maydis.

Q9Y809	NAA25_SCHPO	N-terminal acetyltransferase B complex subunit arm1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9ZNS6	RCI2B_ARATH	Hydrophobic protein RCI2B	9342870	Two homologous low-temperature-inducible genes from Arabidopsis encode highly hydrophobic proteins.

O94358	YHOA_SCHPO	Uncharacterized protein C428.10	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P28329	CLAT_HUMAN	Choline O-acetyltransferase	1339386	Human choline acetyltransferase (CHAT): partial gene sequence and potential control regions.

Q9GZV9	FGF23_HUMAN	Fibroblast growth factor 23	18282132	Overexpression of fibroblast growth factor 23 suppresses osteoblast differentiation and matrix mineralization in vitro.

Q92947	GCDH_HUMAN	Glutaryl-CoA dehydrogenase, mitochondrial	8541831	Cloning of glutaryl-CoA dehydrogenase cDNA, and expression of wild type and mutant enzymes in Escherichia coli.

Q8WUM9	S20A1_HUMAN	Sodium-dependent phosphate transporter 1	8041748	Cell-surface receptors for gibbon ape leukemia virus and amphotropic murine retrovirus are inducible sodium-dependent phosphate symporters.

Q38FA5	RLGM1_TRYBB	RNA-editing ligase 1, mitochondrial	11134327	Association of two novel proteins TbMP52 and TbMP48 with the Trypanosoma brucei RNA editing complex.

Q60714	S27A1_MOUSE	Long-chain fatty acid transport protein 1	12533547	Oligomerization of the murine fatty acid transport protein 1.

P32747	PYRD_SCHPO	Dihydroorotate dehydrogenase, mitochondrial	1409592	Divergent evolution of pyrimidine biosynthesis between anaerobic and aerobic yeasts.

Q8IR79	LIMK1_DROME	LIM domain kinase 1	15572110	Rho GTPases regulate axon growth through convergent and divergent signaling pathways.

Q9VTK2	POMT1_DROME	Protein O-mannosyltransferase 1	16219785	The twisted gene encodes Drosophila protein O-mannosyltransferase 2 and genetically interacts with the rotated abdomen gene encoding Drosophila protein O-mannosyltransferase 1.

P22146	GAS1_YEAST	1,3-beta-glucanosyltransferase GAS1	15781460	Comprehensive proteomic analysis of Saccharomyces cerevisiae cell walls: identification of proteins covalently attached via glycosylphosphatidylinositol remnants or mild alkali-sensitive linkages.

Q10223	POF14_SCHPO	F-box protein pof14	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P99999	CYC_HUMAN	Cytochrome c	9515723	Cytochrome c in the apoptotic and antioxidant cascades.

Q9NQ25	SLAF7_HUMAN	SLAM family member 7	11802771	A novel immunoglobulin superfamily receptor (19A) related to CD2 is expressed on activated lymphocytes and promotes homotypic B-cell adhesion.

Q94ID1	IPT7_ARATH	Adenylate isopentenyltransferase 7, mitochondrial	17062755	Roles of Arabidopsis ATP/ADP isopentenyltransferases and tRNA isopentenyltransferases in cytokinin biosynthesis.

Q9UBW7	ZMYM2_HUMAN	Zinc finger MYM-type protein 2	9576949	Fibroblast growth factor receptor 1 is fused to FIM in stem-cell myeloproliferative disorder with t(8;13)(p12;q12).

Q96JB3	HIC2_HUMAN	Hypermethylated in cancer 2 protein	11554746	Characterization of HRG22, a human homologue of the putative tumor suppressor gene HIC1.

P38839	SPL2_YEAST	Putative cyclin-dependent kinase inhibitor SPL2	14562095	Global analysis of protein localization in budding yeast.

P16152	CBR1_HUMAN	Carbonyl reductase [NADPH] 1	9740676	Mapping of a novel human carbonyl reductase, CBR3, and ribosomal pseudogenes to human chromosome 21q22.2.

Q6QI06	RICTR_MOUSE	Rapamycin-insensitive companion of mTOR	16962829	Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability.

P02679	FIBG_HUMAN	Fibrinogen gamma chain	8470043	Paris I dysfibrinogenemia: a point mutation in intron 8 results in insertion of a 15 amino acid sequence in the fibrinogen gamma-chain.

Q08117	AES_HUMAN	Amino-terminal enhancer of split	11390640	Pf1, a novel PHD zinc finger protein that links the TLE corepressor to the mSin3A-histone deacetylase complex.

P78348	ACCN2_HUMAN	Amiloride-sensitive cation channel 2, neuronal	11802773	Interaction of the synaptic protein PICK1 (protein interacting with C kinase 1) with the non-voltage gated sodium channels BNC1 (brain Na+ channel 1) and ASIC (acid-sensing ion channel).

P27352	IF_HUMAN	Gastric intrinsic factor	14695536	A genetic polymorphism in the coding region of the gastric intrinsic factor gene (GIF) is associated with congenital intrinsic factor deficiency.

Q9NII1	ADAR_DROME	Double-stranded RNA-specific editase Adar	10917596	dADAR, a Drosophila double-stranded RNA-specific adenosine deaminase is highly developmentally regulated and is itself a target for RNA editing.

Q9C8N5	STOP1_ARATH	Protein SENSITIVE TO PROTON RHIZOTOXICITY 1	17535918	Zinc finger protein STOP1 is critical for proton tolerance in Arabidopsis and coregulates a key gene in aluminum tolerance.

P53971	FAP1_YEAST	FKBP12-associated protein 1	10998178	FAP1, a homologue of human transcription factor NF-X1, competes with rapamycin for binding to FKBP12 in yeast.

Q12146	PSF3_YEAST	DNA replication complex GINS protein PSF3	12730134	GINS, a novel multiprotein complex required for chromosomal DNA replication in budding yeast.

P06400	RB_HUMAN	Retinoblastoma-associated protein	15542589	LIM domains-containing protein 1 (LIMD1), a tumor suppressor encoded at chromosome 3p21.3, binds pRB and represses E2F-driven transcription.

O13759	CSX1_SCHPO	RNA-binding post-transcriptional regulator csx1	14633985	RNA-binding protein Csx1 mediates global control of gene expression in response to oxidative stress.

Q9PU29	CCKN_STRCA	Cholecystokinin	11072120	Identification of ostrich and chicken cholecystokinin cDNA and intestinal peptides.

P49863	GRAK_HUMAN	Granzyme K	8656064	Cloning and expression of a second human natural killer cell granule tryptase, HNK-Tryp-2/granzyme 3.

Q562F6	SGOL2_HUMAN	Shugoshin-like 2	17485487	Tripin/hSgo2 recruits MCAK to the inner centromere to correct defective kinetochore attachments.

Q15319	PO4F3_HUMAN	POU domain, class 4, transcription factor 3	7623109	The Brn-3 family of POU-domain factors: primary structure, binding specificity, and expression in subsets of retinal ganglion cells and somatosensory neurons.

O88917	LPHN1_RAT	Latrophilin-1	9261169	Alpha-latrotoxin receptor, latrophilin, is a novel member of the secretin family of G protein-coupled receptors.

P83369	LSM11_HUMAN	U7 snRNA-associated Sm-like protein LSm11	16914750	ZFP100, a component of the active U7 snRNP limiting for histone pre- mRNA processing, is required for entry into S phase.

P23615	SPT6_YEAST	Transcription elongation factor SPT6	16455495	Transcriptional activators are dispensable for transcription in the absence of Spt6-mediated chromatin reassembly of promoter regions.

O80437	GPAT6_ARATH	Glycerol-3-phosphate acyltransferase 6	12897259	Arabidopsis AtGPAT1, a member of the membrane-bound glycerol-3- phosphate acyltransferase gene family, is essential for tapetum differentiation and male fertility.

Q5YD48	A1CF_MOUSE	APOBEC1 complementation factor	16055734	Targeted deletion of the murine apobec-1 complementation factor (acf) gene results in embryonic lethality.

Q9UH92	MLX_HUMAN	Max-like protein X	10593926	Mlx, a novel Max-like bHLHZip protein that interacts with the Max network of transcription factors.

P42839	VNX1_YEAST	Low affinity vacuolar monovalent cation/H(+) antiporter	17588950	Identification and characterization of Vnx1p, a novel type of vacuolar monovalent cation/H+ antiporter of Saccharomyces cerevisiae.

P84074	HPCA_HUMAN	Neuron-specific calcium-binding protein hippocalcin	9931466	Genomic structure and chromosomal mapping of the human and mouse hippocalcin genes.

Q5AK25	PALB_CANAL	Calpain-like protease palB/RIM13	15189995	Candida albicans Rim13p, a protease required for Rim101p processing at acidic and alkaline pHs.

P43586	LOC1_YEAST	60S ribosomal subunit assembly/export protein LOC1	16871394	Loc1p is required for efficient assembly and nuclear export of the 60S ribosomal subunit.

Q96B02	UBE2W_HUMAN	Probable ubiquitin-conjugating enzyme E2 W	20061386	The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.

Q8IWV2	CNTN4_HUMAN	Contactin-4	15106122	Disruption of contactin 4 (CNTN4) results in developmental delay and other features of 3p deletion syndrome.

Q92956	TNR14_HUMAN	Tumor necrosis factor receptor superfamily member 14	9162022	Herpesvirus entry mediator, a member of the tumor necrosis factor receptor (TNFR) family, interacts with members of the TNFR-associated factor family and activates the transcription factors NF-kappaB and AP-1.

O48809	LRX2_ARATH	Leucine-rich repeat extensin-like protein 2	16287169	Arabidopsis cell wall proteome defined using multidimensional protein identification technology.

Q9VZL7	GR63A_DROME	Gustatory and odorant receptor 63a	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

Q6NSQ9	G6PC3_MOUSE	Glucose-6-phosphatase 3	15661744	Brain contains a functional glucose-6-phosphatase complex capable of endogenous glucose production.

Q9VJF2	GR36B_DROME	Putative gustatory receptor 36b	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

P20395	FSHR_RAT	Follicle-stimulating hormone receptor	2126341	The testicular receptor for follicle stimulating hormone: structure and functional expression of cloned cDNA.

Q90Z12	HES4A_XENLA	Transcription factor HES-4-A	19253409	Xhairy2 functions in Xenopus lens development by regulating p27(xic1) expression.

Q9ULW0	TPX2_HUMAN	Targeting protein for Xklp2	9207457	p100: a novel proliferation-associated nuclear protein specifically restricted to cell cycle phases S, G2, and M.

Q10422	YDC1_SCHPO	Uncharacterized RNA-binding protein C25G10.01	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O35973	PER1_MOUSE	Period circadian protein homolog 1	11591712	Nuclear export of mammalian PERIOD proteins.

Q60843	KLF2_MOUSE	Krueppel-like factor 2	7565748	Isolation of a gene encoding a functional zinc finger protein homologous to erythroid Kruppel-like factor: identification of a new multigene family.

P12956	XRCC6_HUMAN	X-ray repair cross-complementing protein 6	12145306	Regulation of osteocalcin gene expression by a novel Ku antigen transcription factor complex.

Q811Q2	CLIC6_RAT	Chloride intracellular channel protein 6	14499480	CLIC6, a member of the intracellular chloride channel family, interacts with dopamine D(2)-like receptors.

Q61696	HS71A_MOUSE	Heat shock 70 kDa protein 1A	19052621	Ktu/PF13 is required for cytoplasmic pre-assembly of axonemal dyneins.

Q9P1W9	PIM2_HUMAN	Serine/threonine-protein kinase pim-2	9804974	The human Pim-2 proto-oncogene and its testicular expression.

P11914	MPPA_YEAST	Mitochondrial-processing peptidase subunit alpha	3061808	Import of proteins into yeast mitochondria: the nuclear MAS2 gene encodes a component of the processing protease that is homologous to the MAS1-encoded subunit.

P46639	KNAT1_ARATH	Homeobox protein knotted-1-like 1	11701881	The Arabidopsis BELL1 and KNOX TALE homeodomain proteins interact through a domain conserved between plants and animals.

Q9M2E2	SDR1_ARATH	(+)-neomenthol dehydrogenase	18599651	A role for a menthone reductase in resistance against microbial pathogens in plants.

Q18825	BAR1_CAEEL	Beta-catenin/armadillo-related protein 1	17601533	Two functionally distinct axin-like proteins regulate canonical Wnt signaling in C. elegans.

Q15506	SP17_HUMAN	Sperm surface protein Sp17	8688458	Cloning and sequencing of cDNAs encoding the human sperm protein, Sp17.

O14154	MDE5_SCHPO	Alpha-amylase mde5	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P49354	FNTA_HUMAN	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	8494894	Characterization of recombinant human farnesyl-protein transferase: cloning, expression, farnesyl diphosphate binding, and functional homology with yeast prenyl-protein transferases.

P40007	NOP16_YEAST	Nucleolar protein 16	11583614	Composition and functional characterization of yeast 66S ribosome assembly intermediates.

Q99P30	NUDT7_MOUSE	Peroxisomal coenzyme A diphosphatase NUDT7	11415433	The mouse Nudt7 gene encodes a peroxisomal nudix hydrolase specific for coenzyme A and its derivatives.

P80644	SSUE_ECOLI	FMN reductase	10506196	The Escherichia coli ssuEADCB gene cluster is required for the utilization of sulfur from aliphatic sulfonates and is regulated by the transcriptional activator Cbl.

O77059	CRY1_DROME	Cryptochrome-1	16527739	Drosophila CRYPTOCHROME is a circadian transcriptional repressor.

P14099	PDE2A_BOVIN	cGMP-dependent 3',5'-cyclic phosphodiesterase	1654333	Molecular cloning of a cyclic GMP-stimulated cyclic nucleotide phosphodiesterase cDNA. Identification and distribution of isozyme variants.

Q8TD07	N2DL4_HUMAN	NKG2D ligand 4	15240696	Two human ULBP/RAET1 molecules with transmembrane regions are ligands for NKG2D.

P32891	DLD1_YEAST	D-lactate dehydrogenase [cytochrome] 1, mitochondrial	11502169	Yeast mitochondrial dehydrogenases are associated in a supramolecular complex.

Q02574	MEC3_YEAST	DNA damage checkpoint control protein MEC3	9670034	Mec1p is essential for phosphorylation of the yeast DNA damage checkpoint protein Ddc1p, which physically interacts with Mec3p.

P15877	DHG_ECOLI	Quinoprotein glucose dehydrogenase	2228962	Cloning, mapping, and sequencing of the gene encoding Escherichia coli quinoprotein glucose dehydrogenase.

P85875	WPPM3_POLMJ	Venom peptide PPM3	17559065	Identification of three novel peptides isolated from the venom of the neotropical social wasp Polistes major major.

Q13562	NDF1_HUMAN	Neurogenic differentiation factor 1	8786144	The NEUROD gene maps to human chromosome 2q32 and mouse chromosome 2.

P17096	HMGA1_HUMAN	High mobility group protein HMG-I/HMG-Y	16157300	Protein arginine methyltransferase 6 specifically methylates the nonhistone chromatin protein HMGA1a.

Q66GN2	LRKA3_ARATH	Lectin-domain containing receptor kinase A4.3	18987212	The Arabidopsis a4 subfamily of lectin receptor kinases negatively regulates abscisic acid response in seed germination.

O42869	YF75_SCHPO	Uncharacterized protein C3G9.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q99801	NKX31_HUMAN	Homeobox protein Nkx-3.1	11137288	Full-length cDNA sequence and genomic organization of human NKX3A -- alternative mRNA forms and regulation by both androgens and estrogens.

Q03525	TMA23_YEAST	Protein TMA23	14562095	Global analysis of protein localization in budding yeast.

Q9JMB0	GKAP1_MOUSE	G kinase-anchoring protein 1	10671526	Binding and phosphorylation of a novel male germ cell-specific cGMP- dependent protein kinase-anchoring protein by cGMP-dependent protein kinase Ialpha.

Q9ASS4	Y5838_ARATH	Probably inactive leucine-rich repeat receptor-like protein kinase At5g48380	17644812	A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome.

P20800	EDN2_HUMAN	Endothelin-2	2649896	The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes.

P20449	DBP5_YEAST	ATP-dependent RNA helicase DBP5	15280434	Stress response in yeast mRNA export factor: reversible changes in Rat8p localization are caused by ethanol stress but not heat shock.

Q96Q11	TRNT1_HUMAN	tRNA-nucleotidyltransferase 1, mitochondrial	11256614	Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.

Q96V54	CREB_EMENI	Ubiquitin carboxyl-terminal hydrolase creB	11442830	Carbon catabolite repression in Aspergillus nidulans involves deubiquitination.

Q9H211	CDT1_HUMAN	DNA replication factor Cdt1	11125146	Inhibition of eukaryotic DNA replication by geminin binding to Cdt1.

P52285	SKP1A_DICDI	SCF ubiquitin ligase complex protein SKP1a	9660787	The cytoplasmic F-box binding protein SKP1 contains a novel pentasaccharide linked to hydroxyproline in Dictyostelium.

O14772	FPGT_HUMAN	Fucose-1-phosphate guanylyltransferase	9804772	GDP-L-fucose pyrophosphorylase: purification, cDNA cloning, and properties of the enzyme.

O55100	SNG1_MOUSE	Synaptogyrin-1	10595519	Essential roles in synaptic plasticity for synaptogyrin I and synaptophysin I.

P43883	PLIN2_MOUSE	Perilipin-2	8325636	Structure of the gene encoding mouse adipose differentiation-related protein (ADRP).

P19474	RO52_HUMAN	E3 ubiquitin-protein ligase TRIM21	8666824	Calreticulin binds hYRNA and the 52-kDa polypeptide component of the Ro/SS-A ribonucleoprotein autoantigen.

Q9C0H9	SRCN1_HUMAN	SRC kinase signaling inhibitor 1	17525734	p140Cap protein suppresses tumour cell properties, regulating Csk and Src kinase activity.

Q9ZR03	UCRIA_ARATH	Cytochrome b6-f complex iron-sulfur subunit, chloroplastic	11722777	Cytochrome b6/f mutation specifically affects thermal dissipation of absorbed light energy in Arabidopsis.

P34791	CP20C_ARATH	Peptidyl-prolyl cis-trans isomerase CYP20-3, chloroplastic	15322131	New functions of the thylakoid membrane proteome of Arabidopsis thaliana revealed by a simple, fast, and versatile fractionation strategy.

P48994	TRPL_DROME	Transient-receptor-potential-like protein	9215637	Coassembly of TRP and TRPL produces a distinct store-operated conductance.

Q02223	TNR17_HUMAN	Tumor necrosis factor receptor superfamily member 17	1396583	A new gene, BCM, on chromosome 16 is fused to the interleukin 2 gene by a t(4;16)(q26;p13) translocation in a malignant T cell lymphoma.

O60058	AFG2_SCHPO	ATPase family gene 2 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Y1W0	FAD5A_DICDI	Delta(5) fatty acid desaturase A	15632431	Temperature adaptation in Dictyostelium: role of Delta5 fatty acid desaturase.

P11161	EGR2_HUMAN	Early growth response protein 2	19651900	The HECT-type E3 ubiquitin ligase AIP2 inhibits activation-induced T- cell death by catalyzing EGR2 ubiquitination.

Q9C932	NAC19_ARATH	NAC domain-containing protein 19	12646039	Interactions between plant RING-H2 and plant-specific NAC (NAM/ATAF1/2/CUC2) proteins: RING-H2 molecular specificity and cellular localization.

Q12310	PRR2_YEAST	Serine/threonine-protein kinase PRR2	11337509	Identification of novel pheromone-response regulators through systematic overexpression of 120 protein kinases in yeast.

Q8NI27	THOC2_HUMAN	THO complex subunit 2	17190602	Human mRNA export machinery recruited to the 5' end of mRNA.

Q9NY93	DDX56_HUMAN	Probable ATP-dependent RNA helicase DDX56	10749921	A novel helicase-type protein in the nucleolus: protein NOH61.

Q12873	CHD3_HUMAN	Chromodomain-helicase-DNA-binding protein 3	12505151	Characterization of a new family of proteins that interact with the C-terminal region of the chromatin-remodeling factor CHD-3.

Q18502	FLP09_CAEEL	FMRFamide-like neuropeptides 9	9920762	Isolation, pharmacology and gene organization of KPSFVRFamide: a neuropeptide from Caenorhabditis elegans.

Q9NPA0	CO024_HUMAN	UPF0480 protein C15orf24	12975309	The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

Q6UWV6	ENPP7_HUMAN	Ectonucleotide pyrophosphatase/phosphodiesterase family member 7	12671034	Purification, localization, and expression of human intestinal alkaline sphingomyelinase.

Q02784	GLRX5_YEAST	Monothiol glutaredoxin-5, mitochondrial	11950925	Grx5 is a mitochondrial glutaredoxin required for the activity of iron/sulfur enzymes.

Q24276	CDC37_DROME	Hsp90 co-chaperone Cdc37	8020093	Mutations in Hsp83 and cdc37 impair signaling by the sevenless receptor tyrosine kinase in Drosophila.

Q3V6T2	GRDN_HUMAN	Girdin	15749703	Identification and characterization of GIV, a novel Galpha i/s- interacting protein found on COPI, endoplasmic reticulum-Golgi transport vesicles.

Q3V1G4	OLM2B_MOUSE	Olfactomedin-like protein 2B	15836428	Identification and characterization of photomedins: novel olfactomedin-domain-containing proteins with chondroitin sulphate-E- binding activity.

P11279	LAMP1_HUMAN	Lysosome-associated membrane glycoprotein 1	3131762	Molecular cloning of cDNAs encoding lamp A, a human lysosomal membrane glycoprotein with apparent Mr approximately equal to 120,000.

Q08977	YP260_YEAST	UPF0662 protein YPL260W	14562095	Global analysis of protein localization in budding yeast.

P36776	LONM_HUMAN	Lon protease homolog, mitochondrial	9485316	The human LON protease binds to mitochondrial promoters in a single- stranded, site-specific, strand-specific manner.

P29268	CTGF_MOUSE	Connective tissue growth factor	9184077	Cyr61 and Fisp12 are both ECM-associated signaling molecules: activities, metabolism, and localization during development.

Q91WZ8	DTBP1_MOUSE	Dysbindin	16980328	Dysbindin-1 is a synaptic and microtubular protein that binds brain snapin.

P61023	CHP1_RAT	Calcium-binding protein p22	8626580	A novel Ca2+-binding protein, p22, is required for constitutive membrane traffic.

Q8NI08	NCOA7_HUMAN	Nuclear receptor coactivator 7	10395741	Interactions of nuclear receptor coactivator/corepressor proteins with the aryl hydrocarbon receptor complex.

O75821	EIF3G_HUMAN	Eukaryotic translation initiation factor 3 subunit G	18599441	Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3.

P26270	PSD7_DROME	26S proteasome non-ATPase regulatory subunit 7	10893261	The regulatory complex of Drosophila melanogaster 26S proteasomes. Subunit composition and localization of a deubiquitylating enzyme.

P62168	NCS1_RAT	Neuronal calcium sensor 1	7488079	Regulation of rhodopsin phosphorylation by a family of neuronal calcium sensors.

P51654	GPC3_HUMAN	Glypican-3	17549790	The Simpson-Golabi-Behmel syndrome causative glypican-3, binds to and inhibits the dipeptidyl peptidase activity of CD26.

P50105	TAF4_YEAST	Transcription initiation factor TFIID subunit 4	10788514	Identification of two novel TAF subunits of the yeast Saccharomyces cerevisiae TFIID complex.

P17813	EGLN_HUMAN	Endoglin	7894484	Endoglin, a TGF-beta binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1.

Q9W594	GR02A_DROME	Putative gustatory receptor 2a	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

O94562	YGD3_SCHPO	Uncharacterized aminotransferase C1771.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8WXI7	MUC16_HUMAN	Mucin-16	14676194	Binding of ovarian cancer antigen CA125/MUC16 to mesothelin mediates cell adhesion.

O14098	CTK1_SCHPO	CTD kinase subunit alpha	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

B0ZTE2	SOX14_XENLA	Transcription factor Sox-14	18956331	Cloning and developmental expression of the soxB2 genes, sox14 and sox21, during Xenopus laevis embryogenesis.

Q9ZSJ6	GRP3S_ARATH	Glycine-rich protein 3 short isoform	11335717	Interaction of the Arabidopsis receptor protein kinase Wak1 with a glycine-rich protein, AtGRP-3.

Q641K1	CBPC1_MOUSE	Cytosolic carboxypeptidase 1	11083920	Regenerating motor neurons express Nna1, a novel ATP/GTP-binding protein related to zinc carboxypeptidases.

Q9VZU2	HHAT_DROME	Protein-cysteine N-palmitoyltransferase Rasp	11748147	Distinct roles of Central missing and Dispatched in sending the Hedgehog signal.

P87050	CDR2_SCHPO	Mitosis inducer protein kinase cdr2	9843577	The cdr2(+) gene encodes a regulator of G2/M progression and cytokinesis in Schizosaccharomyces pombe.

P51142	DVL2_XENLA	Segment polarity protein dishevelled homolog DVL-2	8939601	Analysis of Dishevelled signalling pathways during Xenopus development.

Q8C006	TRI35_MOUSE	Tripartite motif-containing protein 35	14662771	HLS5, a novel RBCC (ring finger, B box, coiled-coil) family member isolated from a hemopoietic lineage switch, is a candidate tumor suppressor.

Q9ER24	ATX10_RAT	Ataxin-10	16714295	Ataxin-10 interacts with O-linked beta-N-acetylglucosamine transferase in the brain.

P62775	MTPN_RAT	Myotrophin	8576259	Cardiac myotrophin exhibits rel/NF-kappa B interacting activity in vitro.

Q3UCQ1	FOXK2_MOUSE	Forkhead box protein K2	16376864	Identification of forkhead transcription factors in cortical and dopaminergic areas of the adult murine brain.

Q9NRD5	PICK1_HUMAN	PRKCA-binding protein	11802773	Interaction of the synaptic protein PICK1 (protein interacting with C kinase 1) with the non-voltage gated sodium channels BNC1 (brain Na+ channel 1) and ASIC (acid-sensing ion channel).

Q08648	SG11B_HUMAN	Sperm-associated antigen 11B	8167223	Molecular cloning and characterization of a novel human sperm antigen (HE2) specifically expressed in the proximal epididymis.

Q9LTW0	ALIS1_ARATH	ALA-interacting subunit 1	18344284	The Arabidopsis P4-ATPase ALA3 localizes to the golgi and requires a beta-subunit to function in lipid translocation and secretory vesicle formation.

Q03652	DML1_YEAST	Protein DML1	12702300	Preliminary characterisation of DML1, an essential Saccharomyces cerevisiae gene related to misato of Drosophila melanogaster.

Q9Y4K3	TRAF6_HUMAN	TNF receptor-associated factor 6	12874243	Pellino3, a novel member of the Pellino protein family, promotes activation of c-Jun and Elk-1 and may act as a scaffolding protein.

P29993	ITPR_DROME	Inositol 1,4,5-trisphosphate receptor	1322910	Molecular cloning and characterization of the inositol 1,4,5- trisphosphate receptor in Drosophila melanogaster.

P40946	ARF3_DROME	ADP-ribosylation factor 3	8063793	Characterization of class II and class III ADP-ribosylation factor genes and proteins in Drosophila melanogaster.

P53981	YNB0_YEAST	Uncharacterized phosphatase YNL010W	14562095	Global analysis of protein localization in budding yeast.

O75943	RAD17_HUMAN	Cell cycle checkpoint protein RAD17	9660800	Identification of a human homologue of the Schizosaccharomyces pombe rad17+ checkpoint gene.

Q12416	WHI5_YEAST	G1-specific transcriptional repressor WHI5	15210111	CDK activity antagonizes Whi5, an inhibitor of G1/S transcription in yeast.

P17065	SEC2_YEAST	Rab guanine nucleotide exchange factor SEC2	12045183	Ypt32 recruits the Sec4p guanine nucleotide exchange factor, Sec2p, to secretory vesicles; evidence for a Rab cascade in yeast.

Q96AP0	ACD_HUMAN	Adrenocortical dysplasia protein homolog	17237768	The POT1-TPP1 telomere complex is a telomerase processivity factor.

Q14542	S29A2_HUMAN	Equilibrative nucleoside transporter 2	9478986	Cloning of the human equilibrative, nitrobenzylmercaptopurine riboside (NBMPR)-insensitive nucleoside transporter ei by functional expression in a transport-deficient cell line.

Q70HW3	SAMC_HUMAN	S-adenosylmethionine mitochondrial carrier protein	14674884	Identification of the human mitochondrial S-adenosylmethionine transporter: bacterial expression, reconstitution, functional characterization and tissue distribution.

Q9BWT7	CAR10_HUMAN	Caspase recruitment domain-containing protein 10	11259443	CARD10 is a novel caspase recruitment domain/membrane-associated guanylate kinase family member that interacts with Bcl10 and activates NF-kappa B.

P22256	GABT_ECOLI	4-aminobutyrate aminotransferase	2178550	Stereospecific production of the herbicide phosphinothricin (glufosinate) by transamination: isolation and characterization of a phosphinothricin-specific transaminase from Escherichia coli.

P42794	RL112_ARATH	60S ribosomal protein L11-2	7655508	Developmental regulation of ribosomal protein L16 genes in Arabidopsis thaliana.

O64764	TRXO1_ARATH	Thioredoxin O1, mitochondrial	11717467	Identification and characterization of a mitochondrial thioredoxin system in plants.

P23467	PTPRB_HUMAN	Receptor-type tyrosine-protein phosphatase beta	19451274	VE-PTP controls blood vessel development by balancing Tie-2 activity.

P48165	CXA8_HUMAN	Gap junction alpha-8 protein	9497259	A missense mutation in the human connexin50 gene (GJA8) underlies autosomal dominant 'zonular pulverulent' cataract, on chromosome 1q.

P47158	CAF17_YEAST	Putative transferase CAF17, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

O88382	MAGI2_RAT	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2	10644767	Three isoforms of synaptic scaffolding molecule and their characterization: multimerization between the isoforms and their interaction with N-methyl-D-aspartate receptors and SAP90/PSD-95- associated protein.

Q99719	SEPT5_HUMAN	Septin-5	9385360	A human gene similar to Drosophila melanogaster peanut maps to the DiGeorge syndrome region of 22q11.

P61077	UB2D3_HUMAN	Ubiquitin-conjugating enzyme E2 D3	8530467	Identification of a family of closely related human ubiquitin conjugating enzymes.

Q9US36	YFZ5_SCHPO	Zinc finger protein C1039.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P84826	SKSP1_ASCTR	Skin secreted peptide 1	15922344	Bradykinin-related peptides and tryptophyllins in the skin secretions of the most primitive extant frog, Ascaphus truei.

Q8R455	TRPM8_RAT	Transient receptor potential cation channel subfamily M member 8	11882888	Identification of a cold receptor reveals a general role for TRP channels in thermosensation.

Q9NYB0	TE2IP_HUMAN	Telomeric repeat-binding factor 2-interacting protein 1	19596235	Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair.

Q60631	GRB2_MOUSE	Growth factor receptor-bound protein 2	11571277	PrPC directly interacts with proteins involved in signaling pathways.

Q62011	PDPN_MOUSE	Podoplanin	12654292	T1alpha, a lung type I cell differentiation gene, is required for normal lung cell proliferation and alveolus formation at birth.

P38345	FMP21_YEAST	Protein FMP21, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

P37137	LHX5_XENLA	LIM/homeobox protein Lhx5	12874135	Selective degradation of excess Ldb1 by Rnf12/RLIM confers proper Ldb1 expression levels and Xlim-1/Ldb1 stoichiometry in Xenopus organizer functions.

Q9UQB3	CTND2_HUMAN	Catenin delta-2	9223106	Presenilin 1 interaction in the brain with a novel member of the Armadillo family.

Q9UTH0	NU132_SCHPO	Nucleoporin nup132	15226438	The fission yeast Nup107-120 complex functionally interacts with the small GTPase Ran/Spi1 and is required for mRNA export, nuclear pore distribution, and proper cell division.

Q13158	FADD_HUMAN	Protein FADD	12702765	Fas-associated death domain protein interacts with methyl-CpG binding domain protein 4: a potential link between genome surveillance and apoptosis.

Q8BG93	NUD15_MOUSE	Probable 7,8-dihydro-8-oxoguanine triphosphatase NUDT15	12767940	Mouse MTH2 protein which prevents mutations caused by 8-oxoguanine nucleotides.

P43587	YPI1_YEAST	Type 1 phosphatases regulator YPI1	14506263	Molecular characterization of Ypi1, a novel Saccharomyces cerevisiae type 1 protein phosphatase inhibitor.

P23928	CRYAB_RAT	Alpha-crystallin B chain	2912453	Alpha-B subunit of lens-specific protein alpha-crystallin is present in other ocular and non-ocular tissues.

O15372	EIF3H_HUMAN	Eukaryotic translation initiation factor 3 subunit H	17581632	Reconstitution reveals the functional core of mammalian eIF3.

Q07488	BCB1_ARATH	Blue copper protein	12805588	Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis.

Q07684	YD233_YEAST	Uncharacterized protein YDL233W	14562095	Global analysis of protein localization in budding yeast.

Q5EBM0	CMPK2_HUMAN	UMP-CMP kinase 2, mitochondrial	17999954	Human UMP-CMP kinase 2, a novel nucleoside monophosphate kinase localized in mitochondria.

Q06146	YL257_YEAST	Uncharacterized protein YLR257W	14562095	Global analysis of protein localization in budding yeast.

P29016	CD1B_HUMAN	T-cell surface glycoprotein CD1b	12118248	Structure of human CD1b with bound ligands at 2.3 A, a maze for alkyl chains.

P25439	BRM_DROME	ATP-dependent helicase brm	10809665	The Drosophila brahma complex is an essential coactivator for the trithorax group protein zeste.

P51512	MMP16_HUMAN	Matrix metalloproteinase-16	7559440	Identification of the second membrane-type matrix metalloproteinase (MT-MMP-2) gene from a human placenta cDNA library. MT-MMPs form a unique membrane-type subclass in the MMP family.

P46935	NEDD4_MOUSE	E3 ubiquitin-protein ligase NEDD4	9182527	Subcellular localization and ubiquitin-conjugating enzyme (E2) interactions of mammalian HECT family ubiquitin protein ligases.

P31232	TAGL_RAT	Transgelin	7954852	Cloning and sequencing of cDNAs encoding the actin cross-linking protein transgelin defines a new family of actin-associated proteins.

O15018	PDZD2_HUMAN	PDZ domain-containing protein 2	11289102	Activated in prostate cancer: a PDZ domain-containing protein highly expressed in human primary prostate tumors.

O42913	NRM1_SCHPO	Transcription factor nrm1	16916637	Constraining G1-specific transcription to late G1 phase: the MBF- associated corepressor Nrm1 acts via negative feedback.

Q8JHI3	AR13B_DANRE	ADP-ribosylation factor-like protein 13B	15269167	A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney.

Q9XWD6	CED1_CAEEL	Cell death abnormality protein 1	18351800	Phagocytic receptor CED-1 initiates a signaling pathway for degrading engulfed apoptotic cells.

P37195	DCTR_ECOLI	HTH-type transcriptional regulator dctR	9811641	atp mutants of Escherichia coli fail to grow on succinate due to a transport deficiency.

P13761	2B17_HUMAN	HLA class II histocompatibility antigen, DRB1-7 beta chain	10609818	Influence of MHC class II genotype on outcome of infection with hepatitis C virus.

Q9C0J8	WDR33_HUMAN	WD repeat-containing protein 33	11162572	A novel WD40 repeat protein, WDC146, highly expressed during spermatogenesis in a stage-specific manner.

Q10425	EIF3B_SCHPO	Eukaryotic translation initiation factor 3 subunit B	15904532	PCI proteins eIF3e and eIF3m define distinct translation initiation factor 3 complexes.

Q13535	ATR_HUMAN	Serine/threonine-protein kinase ATR	14657349	MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation.

Q22866	TPM1_CAEEL	Tropomyosin isoforms a/b/d/f	11901171	Tropomyosin inhibits ADF/cofilin-dependent actin filament dynamics.

Q9P7S3	SSR3_SCHPO	SWI/SNF and RSC complexes subunit ssr3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9HC16	ABC3G_HUMAN	DNA dC->dU-editing enzyme APOBEC-3G	12859895	Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif.

Q86B87	MMD4_DROME	Modifier of mdg4	10790390	Genetic and molecular complexity of the position effect variegation modifier mod(mdg4) in Drosophila.

Q13564	ULA1_HUMAN	NEDD8-activating enzyme E1 regulatory subunit	14557245	APP-BP1 mediates APP-induced apoptosis and DNA synthesis and is increased in Alzheimer's disease brain.

O76061	STC2_HUMAN	Stanniocalcin-2	9723890	Identification of a second stanniocalcin cDNA in mouse and human: stanniocalcin 2.

Q7TNN9	RHCG_RAT	Ammonium transporter Rh type C	16434569	Changes in subcellular distribution of the ammonia transporter, Rhcg, in response to chronic metabolic acidosis.

Q9I9C3	AT233_ANGAN	Sodium/potassium-transporting ATPase subunit beta-233	10896885	Expression of a duplicate Na,K-ATPase beta(1)-isoform in the European eel (Anguilla anguilla).

O14145	TPS2_SCHPO	Trehalose-phosphatase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O14319	CUE5_SCHPO	CUE domain-containing protein 5	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P22518	CLK1_MOUSE	Dual specificity protein kinase CLK1	1825055	A mammalian protein kinase with potential for serine/threonine and tyrosine phosphorylation is related to cell cycle regulators.

P86012	CUTI2_COLKA	Cutinase 2	17043825	Purification and identification of cutinases from Colletotrichum kahawae and Colletotrichum gloeosporioides.

Q9NSA1	FGF21_HUMAN	Fibroblast growth factor 21	10858549	Identification of a novel FGF, FGF-21, preferentially expressed in the liver.

Q8NEB9	PK3C3_HUMAN	Phosphatidylinositol 3-kinase catalytic subunit type 3	7628435	A human phosphatidylinositol 3-kinase complex related to the yeast Vps34p-Vps15p protein sorting system.

Q99437	VATO_HUMAN	V-type proton ATPase 21 kDa proteolipid subunit	9653649	Identification and characterization of the gene encoding a second proteolipid subunit of human vacuolar H(+)-ATPase (ATP6F).

P40206	JLP2_YEAST	Protein JLP2	14562095	Global analysis of protein localization in budding yeast.

P54845	NRL_HUMAN	Neural retina-specific leucine zipper protein	1729696	A conserved retina-specific gene encodes a basic motif/leucine zipper domain.

Q9Z0U0	XPR1_MOUSE	Xenotropic and polytropic retrovirus receptor 1	9988277	Receptors for polytropic and xenotropic mouse leukaemia viruses encoded by a single gene at Rmc1.

O75022	LIRB3_HUMAN	Leukocyte immunoglobulin-like receptor subfamily B member 3	9278324	Molecular identification of a novel family of human Ig superfamily members that possess immunoreceptor tyrosine-based inhibition motifs and homology to the mouse gp49B1 inhibitory receptor.

Q9LVN2	Y5815_ARATH	Probably inactive leucine-rich repeat receptor-like protein kinase At5g58150	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q5HYA8	MKS3_HUMAN	Meckelin	19515853	Ciliary and centrosomal defects associated with mutation and depletion of the Meckel syndrome genes MKS1 and MKS3.

Q9UQC9	CLCA2_HUMAN	Calcium-activated chloride channel regulator 2	10362588	Molecular cloning and transmembrane structure of hCLCA2 from human lung, trachea, and mammary gland.

P78527	PRKDC_HUMAN	DNA-dependent protein kinase catalytic subunit	7671312	DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product.

Q9H7Z7	PGES2_HUMAN	Prostaglandin E synthase 2	15231747	A protein interaction framework for human mRNA degradation.

Q20646	CEP1_CAEEL	Transcription factor cep-1	17186023	Regulation of developmental rate and germ cell proliferation in Caenorhabditis elegans by the p53 gene network.

Q13555	KCC2G_HUMAN	Calcium/calmodulin-dependent protein kinase type II subunit gamma	9060999	Identification of novel human tumor cell-specific CaMK-II variants.

Q03169	TNAP2_HUMAN	Tumor necrosis factor alpha-induced protein 2	1374453	Cloning of a novel tumor necrosis factor-alpha-inducible primary response gene that is differentially expressed in development and capillary tube-like formation in vitro.

Q64666	SNAT_RAT	Serotonin N-acetyltransferase	8770929	Melatonin synthesis: analysis of the more than 150-fold nocturnal increase in serotonin N-acetyltransferase messenger ribonucleic acid in the rat pineal gland.

Q99972	MYOC_HUMAN	Myocilin	9169133	A novel myosin-like protein (myocilin) expressed in the connecting cilium of the photoreceptor: molecular cloning, tissue expression, and chromosomal mapping.

P41958	CED9_CAEEL	Apoptosis regulator ced-9	9604928	The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9.

P38086	RDH54_YEAST	DNA repair and recombination protein RDH54	10970884	Promotion of Rad51-dependent D-loop formation by yeast recombination factor Rdh54/Tid1.

Q8VI75	IPO4_MOUSE	Importin-4	11823430	Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains.

O42853	RPAP2_SCHPO	Putative RNA polymerase II subunit B1 CTD phosphatase rtr1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P10676	NINAC_DROME	Neither inactivation nor afterpotential protein C	2449973	The Drosophila ninaC locus encodes two photoreceptor cell specific proteins with domains homologous to protein kinases and the myosin heavy chain head.

P21127	CD11B_HUMAN	Cell division protein kinase 11B	1639388	Structure and expression of the human p58clk-1 protein kinase chromosomal gene.

O43688	LPP2_HUMAN	Lipid phosphate phosphohydrolase 2	9705349	Human type 2 phosphatidic acid phosphohydrolases. Substrate specificity of the type 2a, 2b, and 2c enzymes and cell surface activity of the 2a isoform.

O94345	RM08_SCHPO	60S ribosomal protein L8, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q21441	KI26L_CAEEL	Kinesin-like protein vab-8	9581759	vab-8 is a key regulator of posteriorly directed migrations in C. elegans and encodes a novel protein with kinesin motor similarity.

Q14919	NC2A_HUMAN	Dr1-associated corepressor	8670811	A mechanism for repression of class II gene transcription through specific binding of NC2 to TBP-promoter complexes via heterodimeric histone fold domains.

P78332	RBM6_HUMAN	RNA-binding protein 6	10352938	A comparison of genomic structures and expression patterns of two closely related flanking genes in a critical lung cancer region at 3p21.3.

Q8GT95	PGIP1_ORYSJ	Polygalacturonase inhibitor 1	14750524	The OsFOR1 gene encodes a polygalacturonase-inhibiting protein (PGIP) that regulates floral organ number in rice.

P37617	ATZN_ECOLI	Lead, cadmium, zinc and mercury-transporting ATPase	9405611	The zntA gene of Escherichia coli encodes a Zn(II)-translocating P- type ATPase.

O13612	NEP2_SCHPO	NEDD8-specific protease 2	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

Q9UNW9	NOVA2_HUMAN	RNA-binding protein Nova-2	10735272	ANOVA, a putative astrocytic RNA binding protein gene that maps to chromosome 19q13.3.

Q9LHA8	HSP74_ARATH	Heat shock cognate 70 kDa protein 4	20028838	Heat shock protein cognate 70-4 and an E3 ubiquitin ligase, CHIP, mediate plastid-destined precursor degradation through the ubiquitin- 26S proteasome system in Arabidopsis.

P60763	RAC3_HUMAN	Ras-related C3 botulinum toxin substrate 3	11956649	Interaction of the small GTPase Rac3 with NRBP, a protein with a kinase-homology domain.

Q91903	ELAV2_XENLA	ELAV-like protein 2	11780632	A 250-nucleotide UA-rich element in the 3' untranslated region of Xenopus laevis Vg1 mRNA represses translation both in vivo and in vitro.

Q5VTR2	BRE1A_HUMAN	E3 ubiquitin-protein ligase BRE1A	16307923	Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation.

Q67ES7	TR134_RAT	Taste receptor type 2 member 134	15886333	Genomic organization, expression, and function of bitter taste receptors (T2R) in mouse and rat.

Q9NRD8	DUOX2_HUMAN	Dual oxidase 2	10601291	Purification of a novel flavoprotein involved in the thyroid NADPH oxidase. Cloning of the porcine and human cDNAs.

Q9HDW7	ATC2_SCHPO	Calcium-transporting ATPase 2	15470240	Schizosaccharomyces pombe Pmr1p is essential for cell wall integrity and is required for polarized cell growth and cytokinesis.

Q9HBJ0	PLAC1_HUMAN	Placenta-specific protein 1	10995572	PLAC1, an Xq26 gene with placenta-specific expression.

P12294	ENS2_YEAST	Endonuclease SceI small subunit	10464305	Stable association of 70-kDa heat shock protein induces latent multisite specificity of a unisite-specific endonuclease in yeast mitochondria.

P53039	YIP1_YEAST	Protein transport protein YIP1	12657649	The Yip1p.Yif1p complex is required for the fusion competence of endoplasmic reticulum-derived vesicles.

O00204	ST2B1_HUMAN	Sulfotransferase family cytosolic 2B member 1	9799594	Human hydroxysteroid sulfotransferase SULT2B1: two enzymes encoded by a single chromosome 19 gene.

Q96Q35	AL2SB_HUMAN	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein	11586298	A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2.

Q54WR4	PLDB_DICDI	Phospholipase D B	18164290	Screening of genes involved in cell migration in Dictyostelium.

P20908	CO5A1_HUMAN	Collagen alpha-1(V) chain	2203476	Primary structure of the heparin-binding site of type V collagen.

Q9C5J8	OEP80_ARATH	Outer envelope protein of 80 kDa, chloroplastic	15255865	The chloroplastic protein translocation channel Toc75 and its paralog OEP80 represent two distinct protein families and are targeted to the chloroplastic outer envelope by different mechanisms.

Q9FN52	MAM3_ARATH	Methylthioalkylmalate synthase 3, chloroplastic	17369439	MAM3 catalyzes the formation of all aliphatic glucosinolate chain lengths in Arabidopsis.

P16284	PECA1_HUMAN	Platelet endothelial cell adhesion molecule	1690453	PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily.

P49771	FLT3L_HUMAN	SL cytokine	8180375	Cloning of the human homologue of the murine flt3 ligand: a growth factor for early hematopoietic progenitor cells.

O96008	TOM40_HUMAN	Mitochondrial import receptor subunit TOM40 homolog	11745481	Genetic identity and differential expression of p38.5 (Haymaker) in human malignant and non-malignant cells.

P23895	EMRE_ECOLI	Multidrug transporter emrE	7896833	EmrE, an Escherichia coli 12-kDa multidrug transporter, exchanges toxic cations and H+ and is soluble in organic solvents.

P63228	GMHB_ECOLI	D,D-heptose 1,7-bisphosphate phosphatase	11751812	Biosynthesis pathway of ADP-L-glycero-beta-D-manno-heptose in Escherichia coli.

Q9Y5E7	PCDB2_HUMAN	Protocadherin beta-2	10380929	A striking organization of a large family of human neural cadherin- like cell adhesion genes.

Q0DY72	HS178_ORYSJ	17.8 kDa heat shock protein	19703271	Rice sHsp genes: genomic organization and expression profiling under stress and development.

P05183	CP3A2_RAT	Cytochrome P450 3A2	7979376	Structure of a gene and cDNA of a major constitutive form of testosterone 6 beta-hydroxylase (P450/6 beta A) encoding CYP3A2: comparison of the cDNA with P450PCN2.

Q15413	RYR3_HUMAN	Ryanodine receptor 3	9395096	Molecular cloning and characterization of a human brain ryanodine receptor.

P24100	CDKA1_ARATH	Cyclin-dependent kinase A-1	10420643	A new D-type cyclin of Arabidopsis thaliana expressed during lateral root primordia formation.

O93507	TAL1_DANRE	T-cell acute lymphocytic leukemia protein 1 homolog	9499398	SCL/Tal-1 transcription factor acts downstream of cloche to specify hematopoietic and vascular progenitors in zebrafish.

Q15257	PTPA_HUMAN	Serine/threonine-protein phosphatase 2A activator	16916641	Structure and mechanism of the phosphotyrosyl phosphatase activator.

P31415	CASQ1_HUMAN	Calsequestrin-1	7945294	Molecular cloning of human calmitine, a mitochondrial calcium binding protein, reveals identity with calsequestrine.

Q9US07	ARP8_SCHPO	Probable actin-related protein 8	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

P42830	CXCL5_HUMAN	C-X-C motif chemokine 5	7929219	Cloning and characterization of the human neutrophil-activating peptide (ENA-78) gene.

Q54TN2	MYBC_DICDI	Myb-like protein C	10331990	A myb-related protein required for culmination in Dictyostelium.

Q9H0A6	RNF32_HUMAN	RING finger protein 32	11890671	A double RING-H2 domain in RNF32, a gene expressed during sperm formation.

O60094	DPO5_SCHPO	DNA polymerase V	16816948	Pol5p, a novel binding partner to Cdc10p in fission yeast involved in rRNA production.

Q9NZJ6	COQ3_HUMAN	Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial	10777520	Isolation and functional expression of human COQ3, a gene encoding a methyltransferase required for ubiquinone biosynthesis.

Q9PU41	CCKN_CHICK	Cholecystokinin	11072120	Identification of ostrich and chicken cholecystokinin cDNA and intestinal peptides.

O94556	APC8_SCHPO	Anaphase-promoting complex subunit 8	10526233	Fission yeast APC/cyclosome subunits, Cut20/Apc4 and Cut23/Apc8, in regulating metaphase-anaphase progression and cellular stress responses.

Q09892	HOG1_SCHPO	Mitogen-activated protein kinase sty1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P53090	ARO8_YEAST	Aromatic amino acid aminotransferase 1	9491083	Characterisation of Saccharomyces cerevisiae ARO8 and ARO9 genes encoding aromatic aminotransferases I and II reveals a new aminotransferase subfamily.

P38779	CIC1_YEAST	Proteasome-interacting protein CIC1	11583614	Composition and functional characterization of yeast 66S ribosome assembly intermediates.

Q8N142	PURA1_HUMAN	Adenylosuccinate synthetase isozyme 1	15786719	Molecular cloning and characterization of a novel muscle adenylosuccinate synthetase, AdSSL1, from human bone marrow stromal cells.

Q9US28	YKA1_SCHPO	Uncharacterized FAD-binding protein C1783.01	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O75832	PSD10_HUMAN	26S proteasome non-ATPase regulatory subunit 10	9714768	cDNA cloning and functional analysis of p28 (Nas6p) and p40.5 (Nas7p), two novel regulatory subunits of the 26S proteasome.

Q9C0H9	SRCN1_HUMAN	SRC kinase signaling inhibitor 1	19146815	Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity.

P56544	ACYP1_DROME	Acylphosphatase-1	9744795	Drosophila melanogaster acylphosphatase: a common ancestor for acylphosphatase isoenzymes of vertebrate species.

P36095	VPS24_YEAST	Vacuolar protein-sorting-associated protein 24	12194857	Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting.

P63102	1433Z_RAT	14-3-3 protein zeta/delta	7822263	cDNA cloning and characterization of mitochondrial import stimulation factor (MSF) purified from rat liver cytosol.

P36115	IRS4_YEAST	Increased rDNA silencing protein 4	10082585	A genetic screen for ribosomal DNA silencing defects identifies multiple DNA replication and chromatin-modulating factors.

Q8LEA8	EID1_ARATH	Phytochrome A-associated F-box protein	10760243	eid1: a new Arabidopsis mutant hypersensitive in phytochrome A- dependent high-irradiance responses.

Q03048	COFI_YEAST	Cofilin	8421056	Cofilin is an essential component of the yeast cortical cytoskeleton.

Q04377	LCD1_YEAST	DNA damage checkpoint protein LCD1	11060031	LCD1: an essential gene involved in checkpoint control and regulation of the MEC1 signalling pathway in Saccharomyces cerevisiae.

P39543	SOP4_YEAST	Protein SOP4	12230471	An ER membrane protein, Sop4, facilitates ER export of the yeast plasma membrane [H+]ATPase, Pma1.

Q9BPW9	DHRS9_HUMAN	Dehydrogenase/reductase SDR family member 9	11294878	Characterization of a novel type of human microsomal 3alpha- hydroxysteroid dehydrogenase. Unique tissue distribution and catalytic properties.

Q07979	RSC58_YEAST	Chromatin structure-remodeling complex protein RSC58	12052880	Proteomics of the eukaryotic transcription machinery: identification of proteins associated with components of yeast TFIID by multidimensional mass spectrometry.

P93026	VSR1_ARATH	Vacuolar-sorting receptor 1	10561538	A family of Arabidopsis plasma membrane receptors presenting animal beta-integrin domains.

P58012	FOXL2_HUMAN	Forkhead box protein L2	19744555	Sumoylation of forkhead L2 by Ubc9 is required for its activity as a transcriptional repressor of the Steroidogenic Acute Regulatory gene.

Q5NCQ5	DPH1_MOUSE	Diphthamide biosynthesis protein 1	15485916	Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2.

P41145	OPRK_HUMAN	Kappa-type opioid receptor	16431922	GEC1 interacts with the kappa opioid receptor and enhances expression of the receptor.

O75528	TADA3_HUMAN	Transcriptional adapter 3	11564863	Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage- binding factors in vivo.

Q4PIR3	NSE2_SCHPO	E3 SUMO-protein ligase nse2	12966087	Novel essential DNA repair proteins Nse1 and Nse2 are subunits of the fission yeast Smc5-Smc6 complex.

Q96TL7	RAP1_SCHPO	DNA-binding protein rap1	11676924	Telomere binding of the Rap1 protein is required for meiosis in fission yeast.

Q9BGI0	GABT_BOVIN	4-aminobutyrate aminotransferase, mitochondrial	11561735	Molecular cloning and functional expression of bovine brain GABA transaminase.

Q8WZA2	RPGF4_HUMAN	Rap guanine nucleotide exchange factor 4	9856955	A family of cAMP-binding proteins that directly activate rap1.

P52016	CYP8_CAEEL	Peptidyl-prolyl cis-trans isomerase 8	8694762	Cloning and biochemical characterization of the cyclophilin homologues from the free-living nematode Caenorhabditis elegans.

Q9H2S1	KCNN2_HUMAN	Small conductance calcium-activated potassium channel protein 2	10991935	Ca2+-activated K+ channels in human leukemic Jurkat T cells. Molecular cloning, biochemical and functional characterization.

P43428	G6PC_RAT	Glucose-6-phosphatase	8865366	Expression and distribution of glucose-6-phosphatase catalytic subunit messenger RNA and its changes in the diabetic state.

P12956	XRCC6_HUMAN	X-ray repair cross-complementing protein 6	7957065	Human DNA helicase II: a novel DNA unwinding enzyme identified as the Ku autoantigen.

Q9UM54	MYO6_HUMAN	Myosin-VI	16507995	Myosin VI is a mediator of the p53-dependent cell survival pathway.

P10771	H11_CAEEL	Histone H1.1	11245572	A single histone H1 isoform (H1.1) is essential for chromatin silencing and germline development in Caenorhabditis elegans.

P30285	CDK4_MOUSE	Cell division protein kinase 4	19767775	Lysine 269 is essential for cyclin D1 ubiquitylation by the SCF(Fbx4/alphaB-crystallin) ligase and subsequent proteasome-dependent degradation.

P63330	PP2AA_MOUSE	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform	9920888	Identification of a domain of Axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domain.

P38205	NCL1_YEAST	tRNA (cytosine-5-)-methyltransferase NCL1	9767141	NCL1, a novel gene for a non-essential nuclear protein in Saccharomyces cerevisiae.

Q09831	PPK14_SCHPO	Serine/threonine-protein kinase ppk14	15821139	Systematic deletion analysis of fission yeast protein kinases.

Q14002	CEAM7_HUMAN	Carcinoembryonic antigen-related cell adhesion molecule 7	7806520	CGM2, a member of the carcinoembryonic antigen gene family is down- regulated in colorectal carcinomas.

P49805	RGS9_RAT	Regulator of G-protein signaling 9	9765512	Molecular characterization of human and rat RGS9L, a novel splice variant enriched in dopamine target regions, and chromosomal localization of the RGS9 gene.

Q800H9	H6ST2_DANRE	Heparan-sulfate 6-O-sulfotransferase 2	16009360	A unique role for 6-O sulfation modification in zebrafish vascular development.

Q12482	AGC1_YEAST	Mitochondrial aspartate-glutamate transporter AGC1	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P34893	CH10_ARATH	10 kDa chaperonin	9011092	Isolation and characterization of a cDNA encoding mitochondrial chaperonin 10 from Arabidopsis thaliana by functional complementation of an Escherichia coli groES mutant.

O75880	SCO1_HUMAN	Protein SCO1 homolog, mitochondrial	9878253	Identification and characterization of human cDNAs specific to BCS1, PET112, SCO1, COX15, and COX11, five genes involved in the formation and function of the mitochondrial respiratory chain.

P36107	AUR1_YEAST	Inositol phosphorylceramide synthase	19047657	Inhibition of inositol phosphorylceramide synthase by the cyclic peptide aureobasidin A.

Q07843	IRC19_YEAST	Increased recombination centers protein 19	12432101	Parallel phenotypic analysis of sporulation and postgermination growth in Saccharomyces cerevisiae.

Q16667	CDKN3_HUMAN	Cyclin-dependent kinase inhibitor 3	8127873	KAP: a dual specificity phosphatase that interacts with cyclin- dependent kinases.

Q9C1W6	YN59_SCHPO	Uncharacterized protein C713.09	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P87053	POF1_SCHPO	F-box/WD repeat-containing protein pof1	15147268	Molecular interactions of fission yeast Skp1 and its role in the DNA damage checkpoint.

O94645	YBV3_SCHPO	Uncharacterized protein C21.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P31645	SC6A4_HUMAN	Sodium-dependent serotonin transporter	18227069	Serotonin transamidates Rab4 and facilitates its binding to the C terminus of serotonin transporter.

Q06402	1A12_ARATH	1-aminocyclopropane-1-carboxylate synthase 2	12968022	Biochemical diversity among the 1-amino-cyclopropane-1-carboxylate synthase isozymes encoded by the Arabidopsis gene family.

Q704Y3	TRPV1_MOUSE	Transient receptor potential cation channel subfamily V member 1	15194687	2-aminoethoxydiphenyl borate is a common activator of TRPV1, TRPV2, and TRPV3.

P35187	SGS1_YEAST	ATP-dependent helicase SGS1	12200140	Supercomplex formation between Mlh1-Mlh3 and Sgs1-Top3 heterocomplexes in meiotic yeast cells.

Q6SJQ0	CLM8_MOUSE	CMRF35-like molecule 8	12893283	Identification and characterization of a new pair of immunoglobulin- like receptors LMIR1 and 2 derived from murine bone marrow-derived mast cells.

Q42400	AAP1_ARATH	Amino acid permease 1	19392706	AAP1 regulates import of amino acids into developing Arabidopsis embryos.

P46011	NRL4_ARATH	Bifunctional nitrilase/nitrile hydratase NIT4	11060302	The Arabidopsis thaliana isogene NIT4 and its orthologs in tobacco encode beta-cyano-L-alanine hydratase/nitrilase.

Q7SXL3	TBP_DANRE	TATA-box-binding protein	18046332	Initiation of zebrafish haematopoiesis by the TATA-box-binding protein-related factor Trf3.

Q9GYU8	NUP88_DROME	Nuclear pore complex protein Nup88	12653959	Tamo selectively modulates nuclear import in Drosophila.

O94716	FTA4_SCHPO	Kinetochore protein fta4	16079914	Molecular analysis of kinetochore architecture in fission yeast.

P46939	UTRO_HUMAN	Utrophin	8576247	The three human syntrophin genes are expressed in diverse tissues, have distinct chromosomal locations, and each bind to dystrophin and its relatives.

Q6W4X9	MUC6_HUMAN	Mucin-6	7680650	Human gastric mucin. Identification of a unique species by expression cloning.

Q9QXY2	SRCN1_RAT	SRC kinase signaling inhibitor 1	10625663	SNIP, a novel SNAP-25-interacting protein implicated in regulated exocytosis.

O15111	IKKA_HUMAN	Inhibitor of nuclear factor kappa-B kinase subunit alpha	10485710	NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase.

Q86VX2	COMD7_HUMAN	COMM domain-containing protein 7	15799966	COMMD proteins, a novel family of structural and functional homologs of MURR1.

P48546	GIPR_HUMAN	Gastric inhibitory polypeptide receptor	7589426	Molecular cloning, functional expression, and signal transduction of the GIP-receptor cloned from a human insulinoma.

Q21554	DDB1_CAEEL	DNA damage-binding protein 1	17145765	The Caenorhabditis elegans replication licensing factor CDT-1 is targeted for degradation by the CUL-4/DDB-1 complex.

O95163	ELP1_HUMAN	Elongator complex protein 1	9751059	IKAP is a scaffold protein of the IkappaB kinase complex.

Q12830	BPTF_HUMAN	Nucleosome-remodeling factor subunit BPTF	10727212	Fetal Alz-50 clone 1 (FAC1) protein interacts with the Myc-associated zinc finger protein (ZF87/MAZ) and alters its transcriptional activity.

O14926	FSCN2_HUMAN	Fascin-2	10783262	Characterization of human retinal fascin gene (FSCN2) at 17q25: close physical linkage of fascin and cytoplasmic actin genes.

Q99549	MPP8_HUMAN	M-phase phosphoprotein 8	8885239	Identification of novel M phase phosphoproteins by expression cloning.

Q9V3V7	SPC25_DROME	Kinetochore protein Spc25	17412918	Genes required for mitotic spindle assembly in Drosophila S2 cells.

P00508	AATM_CHICK	Aspartate aminotransferase, mitochondrial	8665890	Crystal structures and solution studies of oxime adducts of mitochondrial aspartate aminotransferase.

Q9TVY6	SPE9_CAEEL	Sperm transmembrane protein 9	9546393	The C. elegans spe-9 gene encodes a sperm transmembrane protein that contains EGF-like repeats and is required for fertilization.

P55862	MCM5A_XENLA	DNA replication licensing factor mcm5-A	16369567	The ATPase activity of MCM2-7 is dispensable for pre-RC assembly but is required for DNA unwinding.

Q9PUK8	FZD7A_XENLA	Frizzled-7-A	10862746	Role of frizzled 7 in the regulation of convergent extension movements during gastrulation in Xenopus laevis.

Q9BY84	DUS16_HUMAN	Dual specificity protein phosphatase 16	11489891	MKP-7, a novel mitogen-activated protein kinase phosphatase, functions as a shuttle protein.

Q06481	APLP2_HUMAN	Amyloid-like protein 2	8485127	Molecular cloning of the cDNA for a human amyloid precursor protein homolog: evidence for a multigene family.

O70579	PM34_MOUSE	Peroxisomal membrane protein PMP34	9874197	Identification and characterization of human PMP34, a protein closely related to the peroxisomal integral membrane protein PMP47 of Candida boidinii.

Q54NW7	VAM7A_DICDI	Vesicle-associated membrane protein 7A	12175335	Syntaxin 7, syntaxin 8, Vti1 and VAMP7 (vesicle-associated membrane protein 7) form an active SNARE complex for early macropinocytic compartment fusion in Dictyostelium discoideum.

Q12499	NOP58_YEAST	Nucleolar protein 58	9372940	Nucleolar KKE/D repeat proteins Nop56p and Nop58p interact with Nop1p and are required for ribosome biogenesis.

P63151	2ABA_HUMAN	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform	17245430	A specific PP2A regulatory subunit, B56gamma, mediates DNA damage- induced dephosphorylation of p53 at Thr55.

P39990	SNU13_YEAST	13 kDa ribonucleoprotein-associated protein	14730029	Analysis of Snu13p mutations reveals differential interactions with the U4 snRNA and U3 snoRNA.

P70232	CHL1_MOUSE	Neural cell adhesion molecule L1-like protein	10103075	The close homologue of the neural adhesion molecule L1 (CHL1): patterns of expression and promotion of neurite outgrowth by heterophilic interactions.

O44081	DKC1_DROME	H/ACA ribonucleoprotein complex subunit 4	10087258	minifly, a Drosophila gene required for ribosome biogenesis.

Q38831	IAA13_ARATH	Auxin-responsive protein IAA13	12036262	Genetics of Aux/IAA and ARF action in plant growth and development.

Q05029	BCH1_YEAST	Protein BCH1	17000877	Exomer: a coat complex for transport of select membrane proteins from the trans-Golgi network to the plasma membrane in yeast.

Q8BJ37	TYDP1_MOUSE	Tyrosyl-DNA phosphodiesterase 1	17948061	Spinocerebellar ataxia with axonal neuropathy: consequence of a Tdp1 recessive neomorphic mutation?

Q23121	RSP1_CAEEL	Probable splicing factor, arginine/serine-rich 1	10747030	Functional characterization of SR and SR-related genes in Caenorhabditis elegans.

Q99PW8	KIF17_MOUSE	Kinesin-like protein KIF17	10846156	Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor- containing vesicle transport.

Q9ZUH3	PUP5_ARATH	Probable purine permease 5	10662864	A new family of high-affinity transporters for adenine, cytosine, and purine derivatives in Arabidopsis.

O95684	FR1OP_HUMAN	FGFR1 oncogene partner	16690081	Structure of the N-terminal domain of the FOP (FGFR1OP) protein and implications for its dimerization and centrosomal localization.

Q00403	TF2B_HUMAN	Transcription initiation factor IIB	7671313	Solution structure of the C-terminal core domain of human TFIIB: similarity to cyclin A and interaction with TATA-binding protein.

Q9LUV1	PMEI2_ARATH	Pectinesterase inhibitor 2	17971035	Elaborate spatial patterning of cell-wall PME and PMEI at the pollen tube tip involves PMEI endocytosis, and reflects the distribution of esterified and de-esterified pectins.

P25069	CALM2_ARATH	Calmodulin-2/3/5	1627778	Structure and expression of the Arabidopsis CaM-3 calmodulin gene.

O59764	YJMB_SCHPO	Uncharacterized membrane protein C1020.11c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9DAD6	PROF3_MOUSE	Profilin-3	11867228	Genomic organization of profilin-III and evidence for a transcript expressed exclusively in testis.

Q90VV1	HES4B_XENLA	Transcription factor HES-4-B	18710660	Hairy2 functions through both DNA-binding and non DNA-binding mechanisms at the neural plate border in Xenopus.

Q06735	ATPAM_BETVU	ATP synthase subunit alpha, mitochondrial	8358823	The sugar beet mitochondrial gene for the ATPase alpha-subunit: sequence, transcription and rearrangements in cytoplasmic male-sterile plants.

P81912	OR23A_DROME	Odorant receptor 23a	10089887	A spatial map of olfactory receptor expression in the Drosophila antenna.

Q6IRB2	HES1A_XENLA	Transcription factor HES-1-A	11677053	Repression of XMyoD expression and myogenesis by Xhairy-1 in Xenopus early embryo.

O43505	B3GN1_HUMAN	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase	9405606	Expression cloning of cDNA encoding a human beta-1,3-N- acetylglucosaminyltransferase that is essential for poly-N- acetyllactosamine synthesis.

Q96JK2	DCAF5_HUMAN	DDB1- and CUL4-associated factor 5	16949367	A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1.

P49427	UB2R1_HUMAN	Ubiquitin-conjugating enzyme E2 R1	10373550	Human Cdc34 and Rad6B ubiquitin-conjugating enzymes target repressors of cyclic AMP-induced transcription for proteolysis.

Q9V3U9	SLMO_DROME	Protein slowmo	14673704	Mutation in slowmo causes defects in Drosophila larval locomotor behaviour.

P01880	IGHD_HUMAN	Ig delta chain C region	6787589	Primary structure of the Fc region of human immunoglobulin D: implications for evolutionary origin and biological function.

Q9BW27	NUP85_HUMAN	Nuclear pore complex protein Nup85	15146057	The entire Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis.

Q08179	MDM38_YEAST	Mitochondrial distribution and morphology protein 38	11907266	Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae.

P42734	CADH9_ARATH	Probable cinnamyl alcohol dehydrogenase 9	16832689	Evidence for a role of AtCAD 1 in lignification of elongating stems of Arabidopsis thaliana.

P06839	RAD3_YEAST	DNA repair helicase RAD3	14500720	Revised subunit structure of yeast transcription factor IIH (TFIIH) and reconciliation with human TFIIH.

Q20646	CEP1_CAEEL	Transcription factor cep-1	15707894	Translational repression of C. elegans p53 by GLD-1 regulates DNA damage-induced apoptosis.

Q9UW81	NOP1_NEUCR	Opsin-1	10571987	A eukaryotic protein, NOP-1, binds retinal to form an archaeal rhodopsin-like photochemically reactive pigment.

Q3KQ35	S17AA_XENLA	Transcription factor Sox-17-alpha-A	12591603	Redundant early and overlapping larval roles of Xsox17 subgroup genes in Xenopus endoderm development.

Q9UUE7	CDC73_SCHPO	Cell division control protein 73	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

C0LGT6	EFR_ARATH	LRR receptor-like serine/threonine-protein kinase EFR	18158241	Pseudomonas syringae effector AvrPto blocks innate immunity by targeting receptor kinases.

Q26366	VG_DROME	Protein vestigial	9869635	Molecular interactions between Vestigial and Scalloped promote wing formation in Drosophila.

Q56X52	AOX4_ARATH	Alternative oxidase 4, chloroplastic/chromoplastic	9878632	Mutations in the Arabidopsis gene IMMUTANS cause a variegated phenotype by inactivating a chloroplast terminal oxidase associated with phytoene desaturation.

Q9U6B8	CRCM1_DROME	Calcium release-activated calcium channel protein 1	16582901	A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function.

O97159	CHDM_DROME	Chromodomain-helicase-DNA-binding protein Mi-2 homolog	9836641	dMi-2, a hunchback-interacting protein that functions in Polycomb repression.

Q64319	SLC31_RAT	Neutral and basic amino acid transport protein rBAT	1376924	Cloning of a rat kidney cDNA that stimulates dibasic and neutral amino acid transport and has sequence similarity to glucosidases.

Q12983	BNIP3_HUMAN	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3	7954800	Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins.

P84381	XT7_XENTR	Antimicrobial peptide 7	11738090	Antimicrobial peptides isolated from skin secretions of the diploid frog, Xenopus tropicalis (Pipidae).

Q99ME6	AT1B4_MOUSE	Protein ATP1B4	17592128	Evolution of Na,K-ATPase betam-subunit into a coregulator of transcription in placental mammals.

P25653	FIG2_YEAST	Factor-induced gene 2 protein	11027318	A Saccharomyces gene family involved in invasive growth, cell-cell adhesion, and mating.

P05783	K1C18_HUMAN	Keratin, type I cytoskeletal 18	16424149	Rescue of DeltaF508-CFTR (cystic fibrosis transmembrane conductance regulator) by curcumin: involvement of the keratin 18 network.

P42949	TIM16_YEAST	Mitochondrial import inner membrane translocase subunit TIM16	16105940	Role of Pam16's degenerate J domain in protein import across the mitochondrial inner membrane.

Q08285	RRP40_YEAST	Exosome complex component RRP40	10465791	The yeast exosome and human PM-Scl are related complexes of 3'-->5' exonucleases.

P82650	RT22_HUMAN	28S ribosomal protein S22, mitochondrial	10938081	A proteomics approach to the identification of mammalian mitochondrial small subunit ribosomal proteins.

Q13011	ECH1_HUMAN	Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial	7558027	Isolation and characterization of rat and human cDNAs encoding a novel putative peroxisomal enoyl-CoA hydratase.

O60502	NCOAT_HUMAN	Bifunctional protein NCOAT	9811929	Novel immunogenic antigen homologous to hyaluronidase in meningioma.

Q8WTE7	OR1_ANOGA	Odorant receptor Or1	14724626	Olfaction: mosquito receptor for human-sweat odorant.

P09208	INSR_DROME	Insulin-like receptor	12702880	Axons guided by insulin receptor in Drosophila visual system.

Q8N693	ESX1_HUMAN	Homeobox protein ESX1	15897875	Paired-like homeoprotein ESXR1 acts as a sequence-specific transcriptional repressor of the human K-ras gene.

P31167	ADT1_ARATH	ADP,ATP carrier protein 1, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q8NFZ5	TNIP2_HUMAN	TNFAIP3-interacting protein 2	15169888	ABIN-2 forms a ternary complex with TPL-2 and NF-kappa B1 p105 and is essential for TPL-2 protein stability.

Q9Y7M3	YNT3_SCHPO	FYVE-type zinc finger-containing protein C9B6.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O00421	CCRL2_HUMAN	C-C chemokine receptor-like 2	9473515	Cloning and characterization of a novel human chemokine receptor.

P84832	BRK10_ASCTR	Bradykinin-like peptide AR-10	15922344	Bradykinin-related peptides and tryptophyllins in the skin secretions of the most primitive extant frog, Ascaphus truei.

P38344	REI1_YEAST	Pre-60S factor REI1	14562095	Global analysis of protein localization in budding yeast.

P49017	COQ5_YEAST	Ubiquinone biosynthesis methyltransferase COQ5, mitochondrial	9083049	Characterization of the COQ5 gene from Saccharomyces cerevisiae. Evidence for a C-methyltransferase in ubiquinone biosynthesis.

Q9HC16	ABC3G_HUMAN	DNA dC->dU-editing enzyme APOBEC-3G	14528301	HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation.

Q9U6M3	JBP1_TRYBB	Thymine dioxygenase JBP1	19136460	JBP1 and JBP2 are two distinct thymidine hydroxylases involved in J biosynthesis in genomic DNA of African trypanosomes.

Q9HFR0	CSN2_SCHPO	COP9 signalosome complex subunit 2	11854407	Deletion mutants in COP9/signalosome subunits in fission yeast Schizosaccharomyces pombe display distinct phenotypes.

Q92729	PTPRU_HUMAN	Receptor-type tyrosine-protein phosphatase U	12501215	Physical and functional interaction between receptor-like protein tyrosine phosphatase PCP-2 and beta-catenin.

Q06628	ATG13_YEAST	Autophagy-related protein 13	8224160	Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae.

P70290	EM55_MOUSE	55 kDa erythrocyte membrane protein	19897731	Erythrocyte scaffolding protein p55/MPP1 functions as an essential regulator of neutrophil polarity.

P01610	KV118_HUMAN	Ig kappa chain V-I region WEA	6410398	Amino acid sequence of the Fv region of a human monoclonal IgM (protein WEA) with antibody activity against 3,4-pyruvylated galactose in Klebsiella polysaccharides K30 and K33.

P84637	CYVA_LEOCM	Cycloviolin-A	10813905	Cycloviolins A-D, anti-HIV macrocyclic peptides from Leonia cymosa.

Q9V3N2	OR46B_DROME	Odorant receptor 46a, isoform B	10069338	A novel family of divergent seven-transmembrane proteins: candidate odorant receptors in Drosophila.

Q02246	CNTN2_HUMAN	Contactin-2	8425542	cDNA cloning, structural features, and eucaryotic expression of human TAG-1/axonin-1.

P53080	EDC1_YEAST	Enhancer of mRNA-decapping protein 1	14562095	Global analysis of protein localization in budding yeast.

P32971	TNFL8_HUMAN	Tumor necrosis factor ligand superfamily member 8	8391931	CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF.

Q9Y5N5	HEMK2_HUMAN	HemK methyltransferase family member 2	18539146	HemK2 protein, encoded on human chromosome 21, methylates translation termination factor eRF1.

O94495	ELP5_SCHPO	Elongator complex protein 5	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P51793	CLCN4_HUMAN	H(+)/Cl(-) exchange transporter 4	10564087	Identification of an acid-activated Cl- channel from human skeletal muscles.

Q9BQ70	TCF25_HUMAN	Transcription factor 25	16574069	hnulp1, a basic helix-loop-helix protein with a novel transcriptional repressive domain, inhibits transcriptional activity of serum response factor.

Q9XW79	PP4C1_CAEEL	Serine/threonine-protein phosphatase 4 catalytic subunit 1	11896188	Protein phosphatase 4 is required for centrosome maturation in mitosis and sperm meiosis in C. elegans.

Q9UI43	RRMJ2_HUMAN	Putative ribosomal RNA methyltransferase 2	11827451	Identification and characterization of FTSJ2, a novel human nucleolar protein homologous to bacterial ribosomal RNA methyltransferase.

P08574	CY1_HUMAN	Cytochrome c1, heme protein, mitochondrial	2536365	Structural organization of the human mitochondrial cytochrome c1 gene.

P10155	RO60_HUMAN	60 kDa SS-A/Ro ribonucleoprotein	3200833	Molecular analysis of the 60-kDa human Ro ribonucleoprotein.

O17645	HST2_CAEEL	Heparan sulfate 2-O-sulfotransferase hst-2	15671174	Heparan 2-O-sulfotransferase, hst-2, is essential for normal cell migration in Caenorhabditis elegans.

Q9US54	TAF11_SCHPO	Transcription initiation factor TFIID subunit 11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8K203	NEIL3_MOUSE	Endonuclease 8-like 3	20185759	The mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo.

O14792	HS3S1_HUMAN	Heparan sulfate glucosamine 3-O-sulfotransferase 1	9346953	Molecular cloning and expression of mouse and human cDNAs encoding heparan sulfate D-glucosaminyl 3-O-sulfotransferase.

Q1ECV4	TTLL3_DANRE	Tubulin monoglycylase TTLL3	19531357	TTLL3 Is a tubulin glycine ligase that regulates the assembly of cilia.

Q9C5P0	SUVH8_ARATH	Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH8	11691919	The Arabidopsis thaliana genome contains at least 29 active genes encoding SET domain proteins that can be assigned to four evolutionarily conserved classes.

Q9UDT6	CLIP2_HUMAN	CAP-Gly domain-containing linker protein 2	9799601	The murine CYLN2 gene: genomic organization, chromosome localization, and comparison to the human gene that is located within the 7q11.23 Williams syndrome critical region.

Q61345	FOXD1_MOUSE	Forkhead box protein D1	15509772	Foxd1 is required for proper formation of the optic chiasm.

P46460	NSF_MOUSE	Vesicle-fusing ATPase	8082782	Identification of a novel mammalian member of the NSF/CDC48p/Pas1p/TBP-1 family through heterologous expression in yeast.

Q9UHD2	TBK1_HUMAN	Serine/threonine-protein kinase TBK1	16281057	SIKE is an IKK epsilon/TBK1-associated suppressor of TLR3- and virus- triggered IRF-3 activation pathways.

Q42029	PSBP1_ARATH	Oxygen-evolving enhancer protein 2-1, chloroplastic	9039496	Nucleotide sequence of the psbP gene encoding precursor of 23-kDa polypeptide of oxygen-evolving complex in Arabidopsis thaliana and its expression in the wild-type and a constitutively photomorphogenic mutant.

Q92922	SMRC1_HUMAN	SWI/SNF complex subunit SMARCC1	10078207	Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits.

Q91848	SIAM_XENLA	Homeobox protein siamois	7720076	Expression cloning of siamois, a novel Xenopus homeobox gene expressed in dorsal-vegetal cells of blastulae and capable of inducing a complete secondary axis.

P39531	RCY1_YEAST	Recyclin-1	11287615	Skp1p and the F-box protein Rcy1p form a non-SCF complex involved in recycling of the SNARE Snc1p in yeast.

P69054	DHSC_ECOLI	Succinate dehydrogenase cytochrome b556 subunit	9521736	Localization of histidine residues responsible for heme axial ligation in cytochrome b556 of complex II (succinate:ubiquinone oxidoreductase) in Escherichia coli.

O14717	TRDMT_HUMAN	tRNA (cytosine-5-)-methyltransferase	9425235	A candidate mammalian DNA methyltransferase related to pmt1p of fission yeast.

P46531	NOTC1_HUMAN	Neurogenic locus notch homolog protein 1	16530044	Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes.

P62807	H2B1C_HUMAN	Histone H2B type 1-C/E/F/G/I	9119399	Human histone gene organization: nonregular arrangement within a large cluster.

Q9I8D1	MYO6_CHICK	Myosin-VI	11447109	Myosin VI isoform localized to clathrin-coated vesicles with a role in clathrin-mediated endocytosis.

Q9JLB5	ACH10_RAT	Neuronal acetylcholine receptor subunit alpha-10	12401316	Coexpression of alpha 9 and alpha 10 nicotinic acetylcholine receptors in rat dorsal root ganglion neurons.

Q09815	PPK5_SCHPO	Serine/threonine-protein kinase ppk5	15821139	Systematic deletion analysis of fission yeast protein kinases.

Q9QXY2	SRCN1_RAT	SRC kinase signaling inhibitor 1	19146815	Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity.

Q4LB35	FOL1_SCHPO	Folic acid synthesis protein fol1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9M7Q2	AI5L7_ARATH	ABSCISIC ACID-INSENSITIVE 5-like protein 7	16299177	Arabidopsis calcium-dependent protein kinase AtCPK32 interacts with ABF4, a transcriptional regulator of abscisic acid-responsive gene expression, and modulates its activity.

Q14050	CO9A3_HUMAN	Collagen alpha-3(IX) chain	8586434	Molecular cloning of the alpha 3 chain of human type IX collagen: linkage of the gene COL9A3 to chromosome 20q13.3.

O15357	SHIP2_HUMAN	Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2	12504111	The c-Cbl-associated protein and c-Cbl are two new partners of the SH2-containing inositol polyphosphate 5-phosphatase SHIP2.

P43601	ATG18_YEAST	Autophagy-related protein 18	15103325	Svp1p defines a family of phosphatidylinositol 3,5-bisphosphate effectors.

Q8N5H7	SH2D3_HUMAN	SH2 domain-containing protein 3C	10187783	NSP1 defines a novel family of adaptor proteins linking integrin and tyrosine kinase receptors to the c-Jun N-terminal kinase/stress- activated protein kinase signaling pathway.

Q03465	RPN4_YEAST	Protein RPN4	10350051	Rpn4p acts as a transcription factor by binding to PACE, a nonamer box found upstream of 26S proteasomal and other genes in yeast.

O95388	WISP1_HUMAN	WNT1-inducible-signaling pathway protein 1	9843955	WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors.

Q9FU27	C3H2_ORYSJ	Zinc finger CCCH domain-containing protein 2	16778011	A novel nuclear-localized CCCH-type zinc finger protein, OsDOS, is involved in delaying leaf senescence in rice.

P30542	AA1R_HUMAN	Adenosine receptor A1	1530647	Cloning and functional characterization of a human A1 adenosine receptor.

Q9Z0W3	NU160_MOUSE	Nuclear pore complex protein Nup160	11564755	An evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cells.

P32854	PEP12_YEAST	Syntaxin PEP12	8730101	Novel syntaxin homologue, Pep12p, required for the sorting of lumenal hydrolases to the lysosome-like vacuole in yeast.

O13563	RPN13_YEAST	26S proteasome regulatory subunit RPN13	11029046	Proteasomal proteomics: identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes.

Q64430	ATP7A_MOUSE	Copper-transporting ATPase 1	9215672	Molecular basis of the brindled mouse mutant (Mo(br)): a murine model of Menkes disease.

Q92838	EDA_HUMAN	Ectodysplasin-A	11039935	Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors.

P09184	VSR_ECOLI	Very short patch repair protein	10612397	Recognition of a TG mismatch: the crystal structure of very short patch repair endonuclease in complex with a DNA duplex.

P55861	MCM2_XENLA	DNA replication licensing factor mcm2	8917078	Identification of two Xenopus laevis genes, xMCM2 and xCDC46, with sequence homology to MCM genes involved in DNA replication.

Q10107	MRA1_SCHPO	Multicopy suppressor of ras1	9133664	The Schizosaccharomyces pombe mra1 gene, which is required for cell growth and mating, can suppress the mating inefficiency caused by a deficit in the Ras1 activity.

P47756	CAPZB_HUMAN	F-actin-capping protein subunit beta	19922875	The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex.

Q9SZD4	PRS4A_ARATH	26S proteasome regulatory subunit 4 homolog A	15073153	The HALTED ROOT gene encoding the 26S proteasome subunit RPT2a is essential for the maintenance of Arabidopsis meristems.

Q20745	UNC84_CAEEL	Nuclear migration and anchoring protein unc-84	10375507	UNC-84 localizes to the nuclear envelope and is required for nuclear migration and anchoring during C. elegans development.

Q9UHH9	IP6K2_HUMAN	Inositol hexakisphosphate kinase 2	11502751	Identification and characterization of a novel inositol hexakisphosphate kinase.

Q9VT28	FRY_DROME	Protein furry	11526084	The furry gene of Drosophila is important for maintaining the integrity of cellular extensions during morphogenesis.

Q9H4P4	RNF41_HUMAN	E3 ubiquitin-protein ligase NRDP1	18541373	Parkin is ubiquitinated by Nrdp1 and abrogates Nrdp1-induced oxidative stress.

Q06730	ZN33A_HUMAN	Zinc finger protein 33A	8464732	Duplicated KOX zinc finger gene clusters flank the centromere of human chromosome 10: evidence for a pericentric inversion during primate evolution.

Q94AG2	SERK1_ARATH	Somatic embryogenesis receptor kinase 1	11397085	Subcellular localization and oligomerization of the Arabidopsis thaliana somatic embryogenesis receptor kinase 1 protein.

Q64695	EPCR_MOUSE	Endothelial protein C receptor	7890676	Molecular cloning and expression of murine and bovine endothelial cell protein C/activated protein C receptor (EPCR). The structural and functional conservation in human, bovine, and murine EPCR.

O00161	SNP23_HUMAN	Synaptosomal-associated protein 23	8663154	Identification of a novel syntaxin- and synaptobrevin/VAMP-binding protein, SNAP-23, expressed in non-neuronal tissues.

Q9WVE9	ITSN1_RAT	Intersectin-1	10373452	EHSH1/intersectin, a protein that contains EH and SH3 domains and binds to dynamin and SNAP-25. A protein connection between exocytosis and endocytosis?

P15280	GLGS_ORYSJ	Glucose-1-phosphate adenylyltransferase small subunit, chloroplastic/amyloplastic	2545704	The encoded primary sequence of a rice seed ADP-glucose pyrophosphorylase subunit and its homology to the bacterial enzyme.

O75970	MPDZ_HUMAN	Multiple PDZ domain protein	11802782	Evidence that the tandem-pleckstrin-homology-domain-containing protein TAPP1 interacts with Ptd(3,4)P2 and the multi-PDZ-domain- containing protein MUPP1 in vivo.

P25787	PSA2_HUMAN	Proteasome subunit alpha type-2	16548883	Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection.

Q86SC0	SCAB_ORYRH	Scarabaecin	12859949	Scarabaecin, a novel cysteine-containing antifungal peptide from the rhinoceros beetle, Oryctes rhinoceros.

Q9SHE8	PSAF_ARATH	Photosystem I reaction center subunit III, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

P61169	DRD2_RAT	D(2) dopamine receptor	14499480	CLIC6, a member of the intracellular chloride channel family, interacts with dopamine D(2)-like receptors.

Q8MNV0	SPAST_CAEEL	Probable spastin homolog spas-1	17531954	The C. elegans homologue of the spastic paraplegia protein, spastin, disassembles microtubules.

P10505	APC3_SCHPO	Anaphase-promoting complex subunit 3	3283148	A temperature-sensitive mutation of the Schizosaccharomyces pombe gene nuc2+ that encodes a nuclear scaffold-like protein blocks spindle elongation in mitotic anaphase.

Q6PXP0	PHLIP_ANUPH	Phaiodactylipin	15066171	Phaiodactylipin, a glycosylated heterodimeric phospholipase A from the venom of the scorpion Anuroctonus phaiodactylus.

Q9JM63	IRK10_MOUSE	ATP-sensitive inward rectifier potassium channel 10	9647694	CIPP, a novel multivalent PDZ domain protein, selectively interacts with Kir4.0 family members, NMDA receptor subunits, neurexins, and neuroligins.

Q08601	MCA1_YEAST	Metacaspase-1	16301538	Knockout of caspase-like gene, YCA1, abrogates apoptosis and elevates oxidized proteins in Saccharomyces cerevisiae.

Q8R4S0	PP14C_MOUSE	Protein phosphatase 1 regulatory subunit 14C	11812771	KEPI, a PKC-dependent protein phosphatase 1 inhibitor regulated by morphine.

Q9Y794	ORC4_SCHPO	Origin recognition complex subunit 4	10077566	The fission yeast homologue of Orc4p binds to replication origin DNA via multiple AT-hooks.

O88866	HUNK_MOUSE	Hormonally up-regulated neu tumor-associated kinase	10662544	Cloning and characterization of Hunk, a novel mammalian SNF1-related protein kinase.

Q04301	VBA1_YEAST	Vacuolar basic amino acid transporter 1	15572352	A family of basic amino acid transporters of the vacuolar membrane from Saccharomyces cerevisiae.

Q80WK2	OSTB_MOUSE	Organic solute transporter subunit beta	12719432	Functional complementation between a novel mammalian polygenic transport complex and an evolutionarily ancient organic solute transporter, OSTalpha-OSTbeta.

O95267	GRP1_HUMAN	RAS guanyl-releasing protein 1	9789079	A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia.

Q15399	TLR1_HUMAN	Toll-like receptor 1	17889651	Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide.

Q6WKZ7	NOSTN_MOUSE	Nostrin	15596140	Cloning and characterization of mouse disabled 2-interacting protein 2, a mouse orthologue of human NOSTRIN.

Q91YE6	IPO9_MOUSE	Importin-9	11493596	Multiple pathways contribute to nuclear import of core histones.

P18581	CTR2_MOUSE	Low affinity cationic amino acid transporter 2	16670299	Arginine transport via cationic amino acid transporter 2 plays a critical regulatory role in classical or alternative activation of macrophages.

Q90WJ7	SXT1_TAKPA	Saxitoxin and tetrodotoxin-binding protein 1	11722582	Purification, characterization, and cDNA cloning of a novel soluble saxitoxin and tetrodotoxin binding protein from plasma of the puffer fish, Fugu pardalis.

P07858	CATB_HUMAN	Cathepsin B	3463996	Nucleotide and predicted amino acid sequences of cloned human and mouse preprocathepsin B cDNAs.

P51683	CCR2_MOUSE	C-C chemokine receptor type 2	8631787	Molecular cloning and functional expression of murine JE (monocyte chemoattractant protein 1) and murine macrophage inflammatory protein 1alpha receptors: evidence for two closely linked C-C chemokine receptors on chromosome 9.

Q14152	EIF3A_HUMAN	Eukaryotic translation initiation factor 3 subunit A	9150439	The human p167 gene encodes a unique structural protein that contains centrosomin A homology and associates with a multicomponent complex.

Q12487	RM23_YEAST	54S ribosomal protein L23, mitochondrial	9151978	Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae.

P30875	SSR2_MOUSE	Somatostatin receptor type 2	1346068	Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney.

Q9V359	VPS28_DROME	Vacuolar protein sorting-associated protein 28 homolog	15728719	A mutation in dVps28 reveals a link between a subunit of the endosomal sorting complex required for transport-I complex and the actin cytoskeleton in Drosophila.

P53843	IST1_YEAST	Vacuolar protein sorting-associated protein IST1	18032584	Novel Ist1-Did2 complex functions at a late step in multivesicular body sorting.

Q9W747	DRL_DANRE	Zinc finger protein draculin	10433904	Ontogeny and behaviour of early macrophages in the zebrafish embryo.

P32479	HIR1_YEAST	Protein HIR1	9504914	Functional dissection of yeast Hir1p, a WD repeat-containing transcriptional corepressor.

Q9WVH6	ANGP4_MOUSE	Angiopoietin-4	10051567	Angiopoietins 3 and 4: diverging gene counterparts in mice and humans.

Q9Y804	FAN1_SCHPO	Fanconi-associated nuclease 1 homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P19334	TRP_DROME	Transient receptor potential protein	11707492	Phototransduction in Drosophila melanogaster.

P14747	PP2B2_YEAST	Serine/threonine-protein phosphatase 2B catalytic subunit A2	1651503	Yeast has homologs (CNA1 and CNA2 gene products) of mammalian calcineurin, a calmodulin-regulated phosphoprotein phosphatase.

Q9SCR2	KRP2_ARATH	Cyclin-dependent kinase inhibitor 2	15863515	The cyclin-dependent kinase inhibitor KRP2 controls the onset of the endoreduplication cycle during Arabidopsis leaf development through inhibition of mitotic CDKA;1 kinase complexes.

Q12052	TGS1_YEAST	Trimethylguanosine synthase	18840651	Hypermethylation of yeast telomerase RNA by the snRNA and snoRNA methyltransferase Tgs1.

O00483	NDUA4_HUMAN	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

Q9UUM2	SWI1_SCHPO	Mating-type switching protein swi1	15367656	Swi1 and swi3 are components of a replication fork protection complex in fission yeast.

P92979	APR1_ARATH	5'-adenylylsulfate reductase 1, chloroplastic	9653199	Glutaredoxin function for the carboxyl-terminal domain of the plant- type 5'-adenylylsulfate reductase.

P25045	LCB1_YEAST	Serine palmitoyltransferase 1	8058731	The LCB2 gene of Saccharomyces and the related LCB1 gene encode subunits of serine palmitoyltransferase, the initial enzyme in sphingolipid synthesis.

P53671	LIMK2_HUMAN	LIM domain kinase 2	8954941	Subcellular localization and protein interaction of the human LIMK2 gene expressing alternative transcripts with tissue-specific regulation.

O75808	CAN15_HUMAN	Calpain-15	9722942	SOLH, a human homologue of the Drosophila melanogaster small optic lobes gene is a member of the calpain and zinc-finger gene families and maps to human chromosome 16p13.3 near CATM (cataract with microphthalmia).

Q4VBD2	TAPT1_MOUSE	Transmembrane anterior posterior transformation protein 1	17151244	Mutation of a ubiquitously expressed mouse transmembrane protein (Tapt1) causes specific skeletal homeotic transformations.

Q7TSG1	CE120_MOUSE	Centrosomal protein of 120 kDa	17920017	Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool.

Q9C0D3	ZY11B_HUMAN	Protein zyg-11 homolog B	17304241	The Caenorhabditis elegans cell-cycle regulator ZYG-11 defines a conserved family of CUL-2 complex components.

Q9UI95	MD2L2_HUMAN	Mitotic spindle assembly checkpoint protein MAD2B	10527948	Evidence for an interaction of the metalloprotease-disintegrin tumour necrosis factor alpha convertase (TACE) with mitotic arrest deficient 2 (MAD2), and of the metalloprotease-disintegrin MDC9 with a novel MAD2-related protein, MAD2-beta.

O95786	DDX58_HUMAN	Probable ATP-dependent RNA helicase DDX58	19017631	Riplet/RNF135, a RING finger protein, ubiquitinates RIG-I to promote interferon-beta induction during the early phase of viral infection.

P08493	MGP_HUMAN	Matrix Gla protein	9916809	Mutations in the gene encoding the human matrix Gla protein cause Keutel syndrome.

Q9HCC0	MCCB_HUMAN	Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial	11181649	The molecular basis of human 3-methylcrotonyl-CoA carboxylase deficiency.

P84829	SKSP4_ASCTR	Skin secreted peptide 4	15922344	Bradykinin-related peptides and tryptophyllins in the skin secretions of the most primitive extant frog, Ascaphus truei.

P49816	TSC2_RAT	Tuberin	7651821	cDNA structure, alternative splicing and exon-intron organization of the predisposing tuberous sclerosis (Tsc2) gene of the Eker rat model.

Q08417	RSB1_YEAST	Sphingoid long-chain base transporter RSB1	15342785	Cross talk between sphingolipids and glycerophospholipids in the establishment of plasma membrane asymmetry.

P08970	SUHW_DROME	Protein suppressor of hairy wing	7664338	A Drosophila protein that imparts directionality on a chromatin insulator is an enhancer of position-effect variegation.

Q9Z0R4	ITSN1_MOUSE	Intersectin-1	11744688	The activity of the GTPase-activating protein CdGAP is regulated by the endocytic protein intersectin.

Q01105	SET_HUMAN	Protein SET	1630450	Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes: characterization of the set gene.

Q04638	ITT1_YEAST	Translation termination inhibitor protein ITT1	11570975	Itt1p, a novel protein inhibiting translation termination in Saccharomyces cerevisiae.

P83917	CBX1_MOUSE	Chromobox protein homolog 1	8978696	A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors.

O60447	EVI5_HUMAN	Ecotropic viral integration site 5 protein homolog	16439210	The evi5 oncogene regulates cyclin accumulation by stabilizing the anaphase-promoting complex inhibitor emi1.

Q9HC21	TPC_HUMAN	Mitochondrial thiamine pyrophosphate carrier	11226231	The human mitochondrial deoxynucleotide carrier and its role in the toxicity of nucleoside antivirals.

O14147	CHL1_SCHPO	ATP-dependent RNA helicase chl1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O00909	ARF1_DICDI	ADP-ribosylation factor 1	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q99383	HRP1_YEAST	Nuclear polyadenylated RNA-binding protein 4	11344258	Five subunits are required for reconstitution of the cleavage and polyadenylation activities of Saccharomyces cerevisiae cleavage factor I.

Q62151	RAGE_MOUSE	Advanced glycosylation end product-specific receptor	19901339	RAGE-mediated signaling contributes to intraneuronal transport of amyloid-{beta} and neuronal dysfunction.

O94298	YOOF_SCHPO	Uncharacterized hydroxylase C887.15c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q62417	SRBS1_MOUSE	Sorbin and SH3 domain-containing protein 1	11001060	CAP defines a second signalling pathway required for insulin- stimulated glucose transport.

P53905	LSM7_YEAST	U6 snRNA-associated Sm-like protein LSm7	10449419	Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6.U5] tri-snRNP.

O94285	RPC8_SCHPO	DNA-directed RNA polymerase III subunit rpc8	15612920	Rpc25, a conserved RNA polymerase III subunit, is critical for transcription initiation.

P10515	ODP2_HUMAN	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial	3191998	Nucleotide sequence of a cDNA for the dihydrolipoamide acetyltransferase component of human pyruvate dehydrogenase complex.

P10040	CRB_DROME	Protein crumbs	2344615	Crumbs encodes an EGF-like protein expressed on apical membranes of Drosophila epithelial cells and required for organization of epithelia.

Q07980	MLH2_YEAST	DNA mismatch repair protein MLH2	10679328	Discrete in vivo roles for the MutL homologs Mlh2p and Mlh3p in the removal of frameshift intermediates in budding yeast.

P01712	LV209_HUMAN	Ig lambda chain V-II region WIN	102365	Amino acid sequence of the human myeloma lambda chain Win.

Q9MBD8	BI1_ORYSJ	Bax inhibitor 1	10618494	Evolutionally conserved plant homologue of the Bax inhibitor-1 (BI-1) gene capable of suppressing Bax-induced cell death in yeast.

Q923V8	SEP15_RAT	15 kDa selenoprotein	15659830	Prevention against oxidative stress of eukaryotic cell membranes by selenium compounds of the rat.

Q8CG45	ARK72_RAT	Aflatoxin B1 aldehyde reductase member 2	12071861	Novel homodimeric and heterodimeric rat gamma-hydroxybutyrate synthases that associate with the Golgi apparatus define a distinct subclass of aldo-keto reductase 7 family proteins.

P20700	LMNB1_HUMAN	Lamin-B1	7557986	Structural organization of the human gene (LMNB1) encoding nuclear lamin B1.

O94339	MUG96_SCHPO	Meiotically up-regulated gene 96 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q59KZ1	APE2_CANAL	Aminopeptidase 2	18637841	Identification and characterization of CaApe2 -- a neutral arginine/alanine/leucine-specific metallo-aminopeptidase from Candida albicans.

O96005	CLPT1_HUMAN	Cleft lip and palate transmembrane protein 1	9828125	Characterization of a novel gene disrupted by a balanced chromosomal translocation t(2;19)(q11.2;q13.3) in a family with cleft lip and palate.

P35688	LRG1_YEAST	Rho-GTPase-activating protein LRG1	11591390	Functional characterization of the Bag7, Lrg1 and Rgd2 RhoGAP proteins from Saccharomyces cerevisiae.

Q9UNK0	STX8_HUMAN	Syntaxin-8	10198254	Molecular cloning, expression analysis, and chromosomal localization of human syntaxin 8 (STX8).

O74482	YQJ9_SCHPO	Uncharacterized protein C1840.09	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O75369	FLNB_HUMAN	Filamin-B	9694715	A novel human actin-binding protein homologue that binds to platelet glycoprotein Ibalpha.

O81242	RHL1_ARATH	DNA-binding protein RHL1	9649505	The ROOT HAIRLESS 1 gene encodes a nuclear protein required for root hair initiation in Arabidopsis.

Q62915	CSKP_RAT	Peripheral plasma membrane protein CASK	14627983	Carom: a novel membrane-associated guanylate kinase-interacting protein with two SH3 domains.

Q9UEY8	ADDG_HUMAN	Gamma-adducin	8893809	Cloning, expression and chromosome mapping of adducin-like 70 (ADDL), a human cDNA highly homologous to human erythrocyte adducin.

P97583	BKRB1_RAT	B1 bradykinin receptor	10422787	Molecular characterisation of cloned bradykinin B1 receptors from rat and human.

Q15717	ELAV1_HUMAN	ELAV-like protein 1	19029303	Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs.

Q9Y3M2	CBY1_HUMAN	Protein chibby homolog 1	12712206	Chibby, a nuclear beta-catenin-associated antagonist of the Wnt/Wingless pathway.

Q9FDX1	SKIP1_ARATH	F-box protein SKIP1	12795696	Protein interaction analysis of SCF ubiquitin E3 ligase subunits from Arabidopsis.

O94992	HEXI1_HUMAN	Protein HEXIM1	14580347	Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA.

P40471	AYR1_YEAST	NADPH-dependent 1-acyldihydroxyacetone phosphate reductase	10617610	1-acyldihydroxyacetone-phosphate reductase (Ayr1p) of the yeast Saccharomyces cerevisiae encoded by the open reading frame YIL124w is a major component of lipid particles.

P18428	LBP_HUMAN	Lipopolysaccharide-binding protein	2402637	Structure and function of lipopolysaccharide binding protein.

P36607	RAD5_SCHPO	DNA repair protein rad5	8290359	Cloning and characterisation of the Schizosaccharomyces pombe rad8 gene, a member of the SNF2 helicase family.

Q9P7B8	ARB1_SCHPO	Argonaute-binding protein 1	17310250	Two different Argonaute complexes are required for siRNA generation and heterochromatin assembly in fission yeast.

Q7Z465	BNIPL_HUMAN	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein	11741952	The BNIP-2 and Cdc42GAP homology/Sec14p-like domain of BNIP-Salpha is a novel apoptosis-inducing sequence.

O35980	NTHL1_MOUSE	Endonuclease III-like protein 1	9743625	Cloning and characterization of a mouse homologue (mNthl1) of Escherichia coli endonuclease III.

P97836	DLGP1_RAT	Disks large-associated protein 1	9024696	GKAP, a novel synaptic protein that interacts with the guanylate kinase-like domain of the PSD-95/SAP90 family of channel clustering molecules.

O14544	SOCS6_HUMAN	Suppressor of cytokine signaling 6	9344848	Cloning and characterization of novel CIS family genes.

Q9BXS0	COPA1_HUMAN	Collagen alpha-1(XXV) chain	15215182	Mostly separate distributions of CLAC- versus Abeta40- or thioflavin S-reactivities in senile plaques reveal two distinct subpopulations of beta-amyloid deposits.

Q9GZV5	WWTR1_HUMAN	WW domain-containing transcription regulator protein 1	18227151	TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway.

P42862	G6PIA_ORYSJ	Glucose-6-phosphate isomerase, cytosolic A	8722567	Characterization of cDNA encoding for phosphoglucose isomerase of rice (Oryza sativa L.).

Q05547	PP13_DROME	Serine/threonine-protein phosphatase alpha-3 isoform	8383037	Cloning of the fourth functional gene for protein phosphatase 1 in Drosophila melanogaster from its chromosomal location.

P54198	HIRA_HUMAN	Protein HIRA	9710638	Core histones and HIRIP3, a novel histone-binding protein, directly interact with WD repeat protein HIRA.

Q15648	MED1_HUMAN	Mediator of RNA polymerase II transcription subunit 1	10235267	Composite co-activator ARC mediates chromatin-directed transcriptional activation.

Q5B7W2	MANBB_EMENI	Beta-mannosidase B	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

P34619	SOR1_CAEEL	Sop-2-related protein 1	16501168	RNA-binding proteins SOP-2 and SOR-1 form a novel PcG-like complex in C. elegans.

Q03322	TLG1_YEAST	T-SNARE affecting a late Golgi compartment protein 1	12686613	Vps51p mediates the association of the GARP (Vps52/53/54) complex with the late Golgi t-SNARE Tlg1p.

Q12030	TAF10_YEAST	Transcription initiation factor TFIID subunit 10	12138208	Molecular characterization of Saccharomyces cerevisiae TFIID.

Q04637	IF4G1_HUMAN	Eukaryotic translation initiation factor 4 gamma 1	9372926	Human eukaryotic translation initiation factor 4G (eIF4G) possesses two separate and independent binding sites for eIF4A.

Q9P383	NCBP2_SCHPO	Nuclear cap-binding protein subunit 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P89114	SAE3_YEAST	Pachytene arrest protein SAE3	15579681	The budding yeast mei5 and sae3 proteins act together with dmc1 during meiotic recombination.

Q6F2E7	SOX9_XENTR	Transcription factor Sox-9	18816826	Sex-specific expression of SOX9 during gonadogenesis in the amphibian Xenopus tropicalis.

Q9BZJ3	TRYD_HUMAN	Tryptase delta	9920877	Characterization of genes encoding known and novel human mast cell tryptases on chromosome 16p13.3.

Q9NDJ2	DOM_DROME	Helicase domino	17517653	A genome-wide RNA interference screen identifies putative chromatin regulators essential for E2F repression.

Q5FBB7	SGOL1_HUMAN	Shugoshin-like 1	16541025	Shugoshin collaborates with protein phosphatase 2A to protect cohesin.

Q8CE23	OX26_MOUSE	Orexigenic neuropeptide QRFP	16648250	A neuropeptide ligand of the G protein-coupled receptor GPR103 regulates feeding, behavioral arousal, and blood pressure in mice.

Q9NZH7	IL1F8_HUMAN	Interleukin-1 family member 8	10625660	Four new members expand the IL-1 superfamily.

O42958	PAT1_SCHPO	DNA topoisomerase 2-associated protein pat1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q2YFS3	PILRA_MOUSE	Paired immunoglobulin-like type 2 receptor alpha	14970179	Activation of natural killer cells and dendritic cells upon recognition of a novel CD99-like ligand by paired immunoglobulin-like type 2 receptor.

Q62812	MYH9_RAT	Myosin-9	12944413	Glycosyl modification facilitates homo- and hetero-oligomerization of the serotonin transporter. A specific role for sialic acid residues.

O19010	CRIS3_HORSE	Cysteine-rich secretory protein 3	12459257	Molecular characterization of the equine testis-specific protein 1 (TPX1) and acidic epididymal glycoprotein 2 (AEG2) genes encoding members of the cysteine-rich secretory protein (CRISP) family.

Q39238	TSL_ARATH	Serine/threonine-protein kinase TOUSLED	15047893	TOUSLED kinase activity oscillates during the cell cycle and interacts with chromatin regulators.

Q95YI5	US74C_DROME	UDP-sugar transporter UST74c	11533661	UDP-sugar transporter implicated in glycosylation and processing of Notch.

Q9NR46	SHLB2_HUMAN	Endophilin-B2	11161816	SH3GLB, a new endophilin-related protein family featuring an SH3 domain.

Q9V439	MED22_DROME	Mediator of RNA polymerase II transcription subunit 22	12021283	Novel Mediator proteins of the small Mediator complex in Drosophila SL2 cells.

P09446	HSP7A_CAEEL	Heat shock 70 kDa protein A	2841196	The Caenorhabditis elegans hsp70 gene family: a molecular genetic characterization.

P05386	RLA1_HUMAN	60S acidic ribosomal protein P1	3323886	Human acidic ribosomal phosphoproteins P0, P1, and P2: analysis of cDNA clones, in vitro synthesis, and assembly.

Q708W2	FXJ1A_XENLA	Forkhead box protein J1-A	14986136	Isolation and developmental expression of Xenopus FoxJ1 and FoxK1.

O70326	GREM1_MOUSE	Gremlin-1	12808456	Gremlin is the BMP antagonist required for maintenance of Shh and Fgf signals during limb patterning.

P31358	CD52_HUMAN	CAMPATH-1 antigen	1711975	Characterization of the CAMPATH-1 (CDw52) antigen: biochemical analysis and cDNA cloning reveal an unusually small peptide backbone.

O95156	NXPH2_HUMAN	Neurexophilin-2	9570794	Neurexophilins form a conserved family of neuropeptide-like glycoproteins.

P12998	BIOF_ECOLI	8-amino-7-oxononanoate synthase	10642176	Mechanism of 8-amino-7-oxononanoate synthase: spectroscopic, kinetic, and crystallographic studies.

Q9UTS8	YI7B_SCHPO	UPF0695 membrane protein C977.11/PB8B6.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q96B36	AKTS1_HUMAN	Proline-rich AKT1 substrate 1	17386266	PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase.

Q96ST3	SIN3A_HUMAN	Paired amphipathic helix protein Sin3a	17803295	TOPORS functions as a SUMO-1 E3 ligase for chromatin-modifying proteins.

Q04660	ERB1_YEAST	Ribosome biogenesis protein ERB1	11522832	ERB1, the yeast homolog of mammalian Bop1, is an essential gene required for maturation of the 25S and 5.8S ribosomal RNAs.

Q9HC97	GPR35_HUMAN	G-protein coupled receptor 35	9479505	Discovery of three novel G-protein-coupled receptor genes.

Q8K1M5	NPW_RAT	Neuropeptide W	12130646	Identification of neuropeptide W as the endogenous ligand for orphan G-protein-coupled receptors GPR7 and GPR8.

Q9Y709	SKP1_SCHPO	Suppressor of kinetochore protein 1	15147872	Fission yeast Skp1 is required for spindle morphology and nuclear membrane segregation at anaphase.

Q9USQ2	ALP6_SCHPO	Spindle pole body component alp6	11080156	The fission yeast gamma-tubulin complex is required in G(1) phase and is a component of the spindle assembly checkpoint.

P32190	GLPK_YEAST	Glycerol kinase	8358828	The glycerol kinase (GUT1) gene of Saccharomyces cerevisiae: cloning and characterization.

Q9FQ08	KU70_ARATH	ATP-dependent DNA helicase 2 subunit KU70	12148535	Identification of Ku70 and Ku80 homologues in Arabidopsis thaliana: evidence for a role in the repair of DNA double-strand breaks.

Q39024	MPK4_ARATH	Mitogen-activated protein kinase 4	15990873	The MAP kinase substrate MKS1 is a regulator of plant defense responses.

Q8LDP4	CP19D_ARATH	Peptidyl-prolyl cis-trans isomerase CYP19-4	10715321	A conserved domain of the Arabidopsis GNOM protein mediates subunit interaction and cyclophilin 5 binding.

Q56AP7	CRBN_RAT	Protein cereblon	16045448	Identification and functional characterization of cereblon as a binding protein for large-conductance calcium-activated potassium channel in rat brain.

Q42371	ERECT_ARATH	LRR receptor-like serine/threonine-protein kinase ERECTA	16007076	The ERECTA gene regulates plant transpiration efficiency in Arabidopsis.

Q14654	IRK11_HUMAN	ATP-sensitive inward rectifier potassium channel 11	15583126	Molecular basis of Kir6.2 mutations associated with neonatal diabetes or neonatal diabetes plus neurological features.

Q9P7B8	ARB1_SCHPO	Argonaute-binding protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q02159	UBC7_YEAST	Ubiquitin-conjugating enzyme E2 7	9172777	Bacterial expression of the Saccharomyces cerevisiae ubiquitin- conjugating enzyme Ubc7.

Q6ZMJ4	IL34_HUMAN	Interleukin-34	18467591	Discovery of a cytokine and its receptor by functional screening of the extracellular proteome.

P32529	RPA12_YEAST	DNA-directed RNA polymerase I subunit RPA12	8417319	Gene RRN4 in Saccharomyces cerevisiae encodes the A12.2 subunit of RNA polymerase I and is essential only at high temperatures.

Q9Y6M1	IF2B2_HUMAN	Insulin-like growth factor 2 mRNA-binding protein 2	12674497	Identification and characterization of proteins that selectively interact with isoforms of the mRNA binding protein AUF1 (hnRNP D).

P40984	UBC9_SCHPO	SUMO-conjugating enzyme ubc9	12597774	Characterization of SUMO-conjugating enzyme mutants in Schizosaccharomyces pombe identifies a dominant-negative allele that severely reduces SUMO conjugation.

O88597	BECN1_MOUSE	Beclin-1	14657337	Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor.

P42750	UBC6_ARATH	Ubiquitin-conjugating enzyme E2 6	16339806	Genome analysis and functional characterization of the E2 and RING- type E3 ligase ubiquitination enzymes of Arabidopsis.

Q92581	SL9A6_HUMAN	Sodium/hydrogen exchanger 6	11940519	Human Na(+)/H(+) exchanger isoform 6 is found in recycling endosomes of cells, not in mitochondria.

P33552	CKS2_HUMAN	Cyclin-dependent kinases regulatory subunit 2	8211159	Human CksHs2 atomic structure: a role for its hexameric assembly in cell cycle control.

O74205	TOXE_COCCA	Transcription factor TOXE	11698648	Regulation of cyclic peptide biosynthesis in a plant pathogenic fungus by a novel transcription factor.

O43741	AAKB2_HUMAN	5'-AMP-activated protein kinase subunit beta-2	9575201	Identification of a novel AMP-activated protein kinase beta subunit isoform that is highly expressed in skeletal muscle.

Q9WTV7	RNF12_MOUSE	E3 ubiquitin-protein ligase RLIM	16204183	The ubiquitin ligase Rnf6 regulates local LIM kinase 1 levels in axonal growth cones.

Q12285	MDY2_YEAST	Ubiquitin-like protein MDY2	14562095	Global analysis of protein localization in budding yeast.

Q9Z0G0	GIPC1_MOUSE	PDZ domain-containing protein GIPC1	9770488	GIPC, a PDZ domain containing protein, interacts specifically with the C-terminus of RGS-GAIP.

Q03195	RLI1_YEAST	Translation initiation factor RLI1	15660134	Biogenesis of cytosolic ribosomes requires the essential iron-sulphur protein Rli1p and mitochondria.

P0A1E9	CSGB_SALEN	Minor curlin subunit	17379722	AgfC and AgfE facilitate extracellular thin aggregative fimbriae synthesis in Salmonella enteritidis.

Q16718	NDUA5_HUMAN	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

Q5EBH1	RASF5_MOUSE	Ras association domain-containing protein 5	12845325	RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1.

Q62203	SF3A2_MOUSE	Splicing factor 3A subunit 2	11602354	An expressed GNRP-like gene shares a bi-directional promoter with SF3A2 (SAP62) immediately upstream of AMH.

Q9FQ19	SCC13_ARATH	Sister chromatid cohesion 1 protein 3	11410371	Cloning and characterization of two Arabidopsis genes that belong to the RAD21/REC8 family of chromosome cohesin proteins.

Q99MQ4	ASPN_MOUSE	Asporin	11152692	Identification and characterization of asporin. A novel member of the leucine-rich repeat protein family closely related to decorin and biglycan.

Q8WUH2	TGFA1_HUMAN	Transforming growth factor-beta receptor-associated protein 1	9545258	A novel protein distinguishes between quiescent and activated forms of the type I transforming growth factor beta receptor.

Q9SE50	BGL18_ARATH	Beta-glucosidase 18	19147648	Constitutive and inducible ER bodies of Arabidopsis thaliana accumulate distinct beta-glucosidases.

Q14213	IL27B_HUMAN	Interleukin-27 subunit beta	8551575	A novel interleukin-12 p40-related protein induced by latent Epstein- Barr virus infection in B lymphocytes.

Q41951	TIP21_ARATH	Aquaporin TIP2-1	8624437	Characterization of a new vacuolar membrane aquaporin sensitive to mercury at a unique site.

P19623	SPEE_HUMAN	Spermidine synthase	2069720	Human spermidine synthase gene: structure and chromosomal localization.

Q02771	PT117_YEAST	Protein PET117, mitochondrial	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

O15085	ARHGB_HUMAN	Rho guanine nucleotide exchange factor 11	10026210	A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho.

P46951	YPP1_YEAST	Cargo-transport protein YPP1	14690591	Assigning function to yeast proteins by integration of technologies.

O81077	ABAH2_ARATH	Abscisic acid 8'-hydroxylase 2	15044947	The Arabidopsis cytochrome P450 CYP707A encodes ABA 8'-hydroxylases: key enzymes in ABA catabolism.

O14494	LPP1_HUMAN	Lipid phosphate phosphohydrolase 1	9705349	Human type 2 phosphatidic acid phosphohydrolases. Substrate specificity of the type 2a, 2b, and 2c enzymes and cell surface activity of the 2a isoform.

P31539	HS104_YEAST	Heat shock protein 104	16135516	Substrate binding to the molecular chaperone Hsp104 and its regulation by nucleotides.

P28233	CXA6_RAT	Gap junction alpha-6 protein	1370487	Four novel members of the connexin family of gap junction proteins. Molecular cloning, expression, and chromosome mapping.

P50527	STE20_SCHPO	Serine/threonine-protein kinase shk1/pak1	10567532	Direct binding and In vivo regulation of the fission yeast p21- activated kinase shk1 by the SH3 domain protein scd2.

Q9SK27	ENL1_ARATH	Early nodulin-like protein 1	12805588	Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis.

Q9Y232	CDYL1_HUMAN	Chromodomain Y-like protein	10192397	Retroposition of autosomal mRNA yielded testis-specific gene family on human Y chromosome.

Q9Y4E8	UBP15_HUMAN	Ubiquitin carboxyl-terminal hydrolase 15	16005295	The zinc finger of the CSN-associated deubiquitinating enzyme USP15 is essential to rescue the E3 ligase Rbx1.

P40303	PSA7_YEAST	Proteasome component PRE6	9087403	Structure of 20S proteasome from yeast at 2.4-A resolution.

Q07065	CKAP4_HUMAN	Cytoskeleton-associated protein 4	8314870	A reversibly palmitoylated resident protein(p63) of an ER-Golgi intermediate compartment is related to a circulatory shock resuscitation protein.

Q92879	CELF1_HUMAN	CUGBP Elav-like family member 1	10893231	A family of human RNA-binding proteins related to the Drosophila Bruno translational regulator.

Q10315	DPB3_SCHPO	DNA polymerase epsilon subunit C	15388803	Identification and cloning of two putative subunits of DNA polymerase epsilon in fission yeast.

Q23925	YELA_DICDI	Yellow mounds protein A	9254905	Precocious sporulation and developmental lethality in yelA null mutants of Dictyostelium.

Q9V6K1	TPP2_DROME	Tripeptidyl-peptidase 2	9668104	Characterization and cloning of tripeptidyl peptidase II from the fruit fly, Drosophila melanogaster.

Q02038	NEUL_PIG	Neurolysin, mitochondrial	9182559	Targeting of endopeptidase 24.16 to different subcellular compartments by alternative promoter usage.

P38779	CIC1_YEAST	Proteasome-interacting protein CIC1	11500370	Cic1, an adaptor protein specifically linking the 26S proteasome to its substrate, the SCF component Cdc4.

Q9URQ3	TAD3_YEAST	tRNA-specific adenosine deaminase subunit TAD3	10550050	An adenosine deaminase that generates inosine at the wobble position of transfer RNAs.

Q02858	TIE2_MOUSE	Angiopoietin-1 receptor	10557082	Functional interaction of vascular endothelial-protein-tyrosine phosphatase with the angiopoietin receptor Tie-2.

Q63035	NALP6_RAT	NACHT, LRR and PYD domains-containing protein 6	7489366	Identification of a novel dual angiotensin II/vasopressin receptor on the basis of molecular recognition theory.

Q09175	KRP1_SCHPO	Dibasic-processing endoprotease	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P40318	DOA10_YEAST	ERAD-associated E3 ubiquitin-protein ligase DOA10	17051211	Spatially regulated ubiquitin ligation by an ER/nuclear membrane ligase.

P32198	CPT1A_RAT	Carnitine O-palmitoyltransferase 1, liver isoform	14711372	Structural model of carnitine palmitoyltransferase I based on the carnitine acetyltransferase crystal.

O95810	SDPR_HUMAN	Serum deprivation-response protein	2390065	Purification and characterization of a major phosphatidylserine- binding phosphoprotein from human platelets.

Q07970	ATK1_ARATH	Kinesin-1	12112142	Arabidopsis thaliana protein, ATK1, is a minus-end directed kinesin that exhibits non-processive movement.

P25376	AGP1_YEAST	General amino acid permease AGP1	10654085	Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae.

P40645	SOX6_MOUSE	Transcription factor SOX-6	9755172	A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene.

Q96BS2	TESC_HUMAN	Tescalcin	11696366	Human homolog of mouse tescalcin associates with Na(+)/H(+) exchanger type-1.

Q95ZG3	SPC97_DICDI	Spindle pole body component 97	12018385	Molecular analysis of the cytosolic Dictyostelium gamma-tubulin complex.

Q15797	SMAD1_HUMAN	Mothers against decapentaplegic homolog 1	10647776	Remarkable versatility of Smad proteins in the nucleus of transforming growth factor-beta activated cells.

Q6Y5D8	RHG10_MOUSE	Rho GTPase-activating protein 10	11238453	Regulation of CDC42 GTPase by proline-rich tyrosine kinase 2 interacting with PSGAP, a novel pleckstrin homology and Src homology 3 domain containing rhoGAP protein.

P42892	ECE1_HUMAN	Endothelin-converting enzyme 1	7805846	Molecular characterization of human and bovine endothelin converting enzyme (ECE-1).

Q8C255	DPEP2_MOUSE	Dipeptidase 2	12738806	Identification of two additional members of the membrane-bound dipeptidase family.

Q9V3L6	NCBP2_DROME	Nuclear cap-binding protein subunit 2	19632183	Ars2 regulates both miRNA- and siRNA- dependent silencing and suppresses RNA virus infection in Drosophila.

Q9NYW4	TA2R5_HUMAN	Taste receptor type 2 member 5	10761935	T2Rs function as bitter taste receptors.

P36953	AFAM_RAT	Afamin	7509788	New albumin gene 3' adjacent to the alpha 1-fetoprotein locus.

O74461	MU123_SCHPO	Meiotically up-regulated gene 123 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NZU0	FLRT3_HUMAN	Leucine-rich repeat transmembrane protein FLRT3	10644439	Identification of FLRT1, FLRT2, and FLRT3: a novel family of transmembrane leucine-rich repeat proteins.

P49190	PTH2R_HUMAN	Parathyroid hormone 2 receptor	7797535	Identification and functional expression of a receptor selectively recognizing parathyroid hormone, the PTH2 receptor.

P34998	CRFR1_HUMAN	Corticotropin-releasing factor receptor 1	7692441	Expression cloning of a human corticotropin-releasing-factor receptor.

Q99N50	SYTL2_MOUSE	Synaptotagmin-like protein 2	17182843	Exophilin4/Slp2-a targets glucagon granules to the plasma membrane through unique Ca2+-inhibitory phospholipid-binding activity of the C2A domain.

Q8K2X1	AT10D_MOUSE	Probable phospholipid-transporting ATPase VD	12532265	Characterization of a putative type IV aminophospholipid transporter P-type ATPase.

P38255	RXT2_YEAST	Transcriptional regulatory protein RXT2	14562095	Global analysis of protein localization in budding yeast.

Q9WUF1	V1R49_MOUSE	Vomeronasal type-1 receptor 49	11116090	Sequence diversity and genomic organization of vomeronasal receptor genes in the mouse.

P16615	AT2A2_HUMAN	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	10080178	Mutations in ATP2A2, encoding a Ca2+ pump, cause Darier disease.

Q9P7A0	SGO1_SCHPO	Shugoshin-1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12968	NFAC3_HUMAN	Nuclear factor of activated T-cells, cytoplasmic 3	7739550	NFATx, a novel member of the nuclear factor of activated T cells family that is expressed predominantly in the thymus.

P68431	H31_HUMAN	Histone H3.1	11242053	Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins.

P56471	IDH3A_PIG	Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial	2252888	Subunit location and sequences of the cysteinyl peptides of pig heart NAD-dependent isocitrate dehydrogenase.

Q8ND90	PNMA1_HUMAN	Paraneoplastic antigen Ma1	10050892	Ma1, a novel neuron- and testis-specific protein, is recognized by the serum of patients with paraneoplastic neurological disorders.

Q9Y7U8	RM37_SCHPO	60S ribosomal protein L37, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8MSX2	MED6_DROME	Mediator of RNA polymerase II transcription subunit 6	12021283	Novel Mediator proteins of the small Mediator complex in Drosophila SL2 cells.

P29323	EPHB2_HUMAN	Ephrin type-B receptor 2	8589679	Molecular characterization and chromosomal localization of DRT (EPHT3): a developmentally regulated human protein-tyrosine kinase gene of the EPH family.

Q54J35	EXPL7_DICDI	Expansin-like protein 7	19207182	Role of an expansin-like molecule in Dictyostelium morphogenesis and regulation of its gene expression by the signal transducer and activator of transcription protein Dd-STATa.

O74991	POF3_SCHPO	F-box/TPR repeat protein pof3	15147268	Molecular interactions of fission yeast Skp1 and its role in the DNA damage checkpoint.

A0MES8	ABI4_ARATH	Ethylene-responsive transcription factor ABI4	9634591	The Arabidopsis abscisic acid response locus ABI4 encodes an APETALA 2 domain protein.

P40571	RPR2_YEAST	Ribonuclease P protein subunit RPR2	9620854	Purification and characterization of the nuclear RNase P holoenzyme complex reveals extensive subunit overlap with RNase MRP.

P33416	HSP78_YEAST	Heat shock protein 78, mitochondrial	11734006	Importance of two ATP-binding sites for oligomerization, ATPase activity and chaperone function of mitochondrial Hsp78 protein.

Q8K415	S36A2_RAT	Proton-coupled amino acid transporter 2	12727219	Structure, tissue expression pattern, and function of the amino acid transporter rat PAT2.

Q8MIP2	FOXL2_CAPHI	Forkhead box protein L2	16720712	FOXL2 activates P450 aromatase gene transcription: towards a better characterization of the early steps of mammalian ovarian development.

Q670P5	WNT11_XENLA	Protein Wnt-11	18942153	Wnt11r is required for cranial neural crest migration.

Q10432	CCQ1_SCHPO	Coiled-coil quantitatively-enriched protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P81914	OR33A_DROME	Odorant receptor 33a	10069338	A novel family of divergent seven-transmembrane proteins: candidate odorant receptors in Drosophila.

Q9ZUY3	AROD3_ARATH	Arogenate dehydratase 3, chloroplastic	16415218	G-protein-coupled receptor 1, G-protein Galpha-subunit 1, and prephenate dehydratase 1 are required for blue light-induced production of phenylalanine in etiolated Arabidopsis.

Q80W57	ABCG2_RAT	ATP-binding cassette sub-family G member 2	15255930	Functional expression of rat ABCG2 on the luminal side of brain capillaries and its enhancement by astrocyte-derived soluble factor(s).

Q43157	RPE_SPIOL	Ribulose-phosphate 3-epimerase, chloroplastic	8616224	Cloning of the amphibolic Calvin cycle/OPPP enzyme D-ribulose-5- phosphate 3-epimerase (EC 5.1.3.1) from spinach chloroplasts: functional and evolutionary aspects.

Q9DAJ5	DLRB2_MOUSE	Dynein light chain roadblock-type 2	14752807	The Roadblock light chains are ubiquitous components of cytoplasmic dynein that form homo- and heterodimers.

O75925	PIAS1_HUMAN	E3 SUMO-protein ligase PIAS1	15133049	NMR structure of the N-terminal domain of SUMO ligase PIAS1 and its interaction with tumor suppressor p53 and A/T-rich DNA oligomers.

Q9NL98	PRDX_ASCSU	Peroxiredoxin	10704594	Cloning and characterisation of a peroxiredoxin from the swine roundworm Ascaris suum.

Q9Z2V5	HDAC6_MOUSE	Histone deacetylase 6	19893491	CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin.

P34691	FEM3_CAEEL	Sex-determination protein fem-3	12477393	Rapid coevolution of the nematode sex-determining genes fem-3 and tra-2.

Q92831	KAT2B_HUMAN	Histone acetyltransferase KAT2B	10365964	Structure and ligand of a histone acetyltransferase bromodomain.

P15365	DAL5_YEAST	Allantoate permease	3275614	Structure and transcription of the allantoate permease gene (DAL5) from Saccharomyces cerevisiae.

Q04174	SMP3_YEAST	GPI mannosyltransferase 4	11356840	The essential Smp3 protein is required for addition of the side- branching fourth mannose during assembly of yeast glycosylphosphatidylinositols.

P45976	FIP1_YEAST	Pre-mRNA polyadenylation factor FIP1	12819204	Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-ends.

Q09624	LOV1_CAEEL	Location of vulva defective 1	17581863	STAM and Hrs down-regulate ciliary TRP receptors.

Q8R550	SH3K1_MOUSE	SH3 domain-containing kinase-binding protein 1	11152963	SETA is a multifunctional adapter protein with three SH3 domains that binds Grb2, Cbl, and the novel SB1 proteins.

Q9C0U6	XKS1_SCHPO	Xylulose kinase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P36629	U2AF2_SCHPO	Splicing factor U2AF 59 kDa subunit	11686295	Conserved Wat1/Pop3 WD-repeat protein of fission yeast secures genome stability through microtubule integrity and may be involved in mRNA maturation.

P83509	GRLF1_CANFA	Glucocorticoid receptor DNA-binding factor 1	12234678	Molecular cloning, characterization and mapping of the canine glucocorticoid receptor DNA binding factor 1 (GRLF1).

P38260	FES1_YEAST	Hsp70 nucleotide exchange factor FES1	12052876	Nucleotide exchange factor for the yeast Hsp70 molecular chaperone Ssa1p.

Q8QGR0	NXM11_DENAN	Muscarinic m1-toxin1	11562434	Site-directed mutagenesis of m1-toxin1: two amino acids responsible for stable toxin binding to m1 muscarinic receptors.

Q9HAZ2	PRD16_HUMAN	PR domain zinc finger protein 16	14656887	Aberrant expression of the MEL1S gene identified in association with hypomethylation in adult T-cell leukemia cells.

Q6VVB1	NHLC1_HUMAN	E3 ubiquitin-protein ligase NHLRC1	17908927	A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease.

O44342	WBL_DROME	Protein windbeutel	9420336	windbeutel, a gene required for dorsoventral patterning in Drosophila, encodes a protein that has homologies to vertebrate proteins of the endoplasmic reticulum.

P50402	EMD_HUMAN	Emerin	15009215	Emerin binding to Btf, a death-promoting transcriptional repressor, is disrupted by a missense mutation that causes Emery-Dreifuss muscular dystrophy.

P38918	ARK73_RAT	Aflatoxin B1 aldehyde reductase member 3	8234296	An ethoxyquin-inducible aldehyde reductase from rat liver that metabolizes aflatoxin B1 defines a subfamily of aldo-keto reductases.

O49675	CCD4_ARATH	Probable carotenoid cleavage dioxygenase 4, chloroplastic	16414959	Tocopherol cyclase (VTE1) localization and vitamin E accumulation in chloroplast plastoglobule lipoprotein particles.

P27825	CALX_YEAST	Calnexin homolog	7814381	Saccharomyces cerevisiae CNE1 encodes an endoplasmic reticulum (ER) membrane protein with sequence similarity to calnexin and calreticulin and functions as a constituent of the ER quality control apparatus.

P15064	RASG_DICDI	Ras-like protein rasG	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q9P7X2	ELL1_SCHPO	RNA polymerase II elongation factor ell1	17150956	Identification and characterization of a Schizosaccharomyces pombe RNA polymerase II elongation factor with similarity to the metazoan transcription factor ELL.

O95409	ZIC2_HUMAN	Zinc finger protein ZIC 2	9771712	Holoprosencephaly due to mutations in ZIC2, a homologue of Drosophila odd-paired.

P06888	LV109_HUMAN	Ig lambda chain V-I region EPS	3929803	The amino-acid sequence of the variable region of a carbohydrate- containing amyloid fibril protein EPS (immunoglobulin light chain, type lambda).

Q03020	ISU1_YEAST	Iron sulfur cluster assembly protein 1, mitochondrial	10468587	Evidence for a conserved system for iron metabolism in the mitochondria of Saccharomyces cerevisiae.

P09668	CATH_HUMAN	Cathepsin H	2849458	Molecular cloning and sequencing of a cDNA coding for mature human kidney cathepsin H.

P18280	NTF3_RAT	Neurotrophin-3	2164684	Molecular cloning and neurotrophic activities of a protein with structural similarities to nerve growth factor: developmental and topographical expression in the brain.

Q9JHD1	KAT2B_MOUSE	Histone acetyltransferase KAT2B	9742083	Mammalian GCN5 and P/CAF acetyltransferases have homologous amino- terminal domains important for recognition of nucleosomal substrates.

P51668	UB2D1_HUMAN	Ubiquitin-conjugating enzyme E2 D1	8090726	Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53.

Q92613	JADE3_HUMAN	Protein Jade-3	16387653	ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.

O59702	CLR6_SCHPO	Histone deacetylase clr6	12773392	Alp13, an MRG family protein, is a component of fission yeast Clr6 histone deacetylase required for genomic integrity.

Q1PEI6	FACR8_ARATH	Fatty acyl-CoA reductase 8	19062129	Functional expression of five Arabidopsis fatty acyl-CoA reductase genes in Escherichia coli.

Q61039	HAND2_MOUSE	Heart- and neural crest derivatives-expressed protein 2	10924525	The basic helix-loop-helix transcription factors dHAND and eHAND exhibit dimerization characteristics that suggest complex regulation of function.

P28159	SUH_DROME	Suppressor of hairless protein	12642500	A Notch-independent function of Suppressor of Hairless during the development of the bristle sensory organ precursor cell of Drosophila.

O96559	APY_CIMLE	Apyrase	9804829	Purification, cloning, and expression of an apyrase from the bed bug Cimex lectularius. A new type of nucleotide-binding enzyme.

Q9V345	CSN4_DROME	COP9 signalosome complex subunit 4	12737805	The COP9 signalosome promotes degradation of Cyclin E during early Drosophila oogenesis.

P25655	NOT1_YEAST	General negative regulator of transcription subunit 1	7926748	NOT1(CDC39), NOT2(CDC36), NOT3, and NOT4 encode a global-negative regulator of transcription that differentially affects TATA-element utilization.

Q16630	CPSF6_HUMAN	Cleavage and polyadenylation specificity factor subunit 6	9659921	Human pre-mRNA cleavage factor Im is related to spliceosomal SR proteins and can be reconstituted in vitro from recombinant subunits.

Q6FI81	CPIN1_HUMAN	Anamorsin	16957168	Subcellular localization of CIAPIN1.

P32336	NUD1_YEAST	Protein NUD1	10899120	Role of the spindle pole body of yeast in mediating assembly of the prospore membrane during meiosis.

P24392	PEX2_RAT	Peroxisome biogenesis factor 2	8035823	Peroxisome assembly factor 1: nonsense mutation in a peroxisome- deficient Chinese hamster ovary cell mutant and deletion analysis.

Q14562	DHX8_HUMAN	ATP-dependent RNA helicase DHX8	16820410	Novel function of beta-arrestin2 in the nucleus of mature spermatozoa.

Q75JI3	NSF_DICDI	Vesicle-fusing ATPase	10727946	Functional and molecular identification of novel members of the ubiquitous membrane fusion proteins alpha- and gamma-SNAP (soluble N- ethylmaleimide-sensitive factor-attachment proteins) families in Dictyostelium discoideum.

P02511	CRYAB_HUMAN	Alpha-crystallin B chain	19646995	Crystal structures of alpha-crystallin domain dimers of alphaB- crystallin and Hsp20.

P62491	RB11A_HUMAN	Ras-related protein Rab-11A	16148947	Rab11-FIP3 and FIP4 interact with Arf6 and the exocyst to control membrane traffic in cytokinesis.

Q13951	PEBB_HUMAN	Core-binding factor subunit beta	8351518	Fusion between transcription factor CBF beta/PEBP2 beta and a myosin heavy chain in acute myeloid leukemia.

Q9P6P6	RM09_SCHPO	60S ribosomal protein L9, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O64645	SOC1_ARATH	MADS-box protein SOC1	11123798	A MADS domain gene involved in the transition to flowering in Arabidopsis.

Q03936	ZNF92_HUMAN	Zinc finger protein 92	2023909	The evolutionarily conserved Kruppel-associated box domain defines a subfamily of eukaryotic multifingered proteins.

Q13257	MD2L1_HUMAN	Mitotic spindle assembly checkpoint protein MAD2A	18022367	The Mad2 conformational dimer: structure and implications for the spindle assembly checkpoint.

P15380	PUT4_YEAST	Proline-specific permease	10654085	Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae.

Q19967	SC61G_CAEEL	Protein transport protein Sec61 subunit gamma	8707849	emo-1, a Caenorhabditis elegans Sec61p gamma homologue, is required for oocyte development and ovulation.

Q9VGP2	NINAG_DROME	Neither inactivation nor afterpotential protein G	15640158	The Drosophila ninaG oxidoreductase acts in visual pigment chromophore production.

Q25C79	AKIR2_RAT	Akirin-2	18460465	A novel binding factor of 14-3-3beta functions as a transcriptional repressor and promotes anchorage-independent growth, tumorigenicity, and metastasis.

Q9XHE8	C71DI_MENSP	Cytochrome P450 71D18	10415126	Regiospecific cytochrome P450 limonene hydroxylases from mint (Mentha) species: cDNA isolation, characterization, and functional expression of (-)-4S-limonene-3-hydroxylase and (-)-4S-limonene-6- hydroxylase.

Q12431	EMC6_YEAST	Uncharacterized protein YLL014W	19325107	Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum.

Q8L8B8	LOG3_ARATH	Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG3	19837870	Functional analyses of LONELY GUY cytokinin-activating enzymes reveal the importance of the direct activation pathway in Arabidopsis.

Q810F0	PRIMA_MOUSE	Proline-rich membrane anchor 1	11804574	PRiMA: the membrane anchor of acetylcholinesterase in the brain.

Q9P6N1	ATG21_SCHPO	Autophagy-related protein 21	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

Q9UKN8	TF3C4_HUMAN	General transcription factor 3C polypeptide 4	17409385	Identification, molecular cloning, and characterization of the sixth subunit of human transcription factor TFIIIC.

Q39085	DIM_ARATH	Cell elongation protein DIMINUTO	7828854	The DIMINUTO gene of Arabidopsis is involved in regulating cell elongation.

Q9SSE7	AROD2_ARATH	Arogenate dehydratase/prephenate dehydratase 2, chloroplastic	17726025	Phenylalanine biosynthesis in Arabidopsis thaliana. Identification and characterization of arogenate dehydratases.

O64687	TIF5B_ARATH	Protein TIFY 5B	17637677	JAZ repressor proteins are targets of the SCF(COI1) complex during jasmonate signalling.

Q39081	CAL_ARATH	Transcription factor CAULIFLOWER	7824951	Molecular basis of the cauliflower phenotype in Arabidopsis.

P12385	ERF1_YEAST	Eukaryotic peptide chain release factor subunit 1	7556078	The products of the SUP45 (eRF1) and SUP35 genes interact to mediate translation termination in Saccharomyces cerevisiae.

Q8VYR7	BOR1_ARATH	Boron transporter 1	12447444	Arabidopsis boron transporter for xylem loading.

O95998	I18BP_HUMAN	Interleukin-18-binding protein	10023777	Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response.

P32832	RSC7_YEAST	Chromatin structure-remodeling complex subunit RSC7	14562095	Global analysis of protein localization in budding yeast.

Q940M2	AGT21_ARATH	Alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial	12529529	Alanine aminotransferase homologs catalyze the glutamate:glyoxylate aminotransferase reaction in peroxisomes of Arabidopsis.

Q9Y5T5	UBP16_HUMAN	Ubiquitin carboxyl-terminal hydrolase 16	10077596	A mutant deubiquitinating enzyme (Ubp-M) associates with mitotic chromosomes and blocks cell division.

Q9W7F2	WDR1A_XENLA	WD repeat-containing protein 1-A	12055192	Xenopus actin-interacting protein 1 (XAip1) enhances cofilin fragmentation of filaments by capping filament ends.

P46947	CWC26_YEAST	Pre-mRNA-splicing factor CWC26	11452010	A genomic study of the bipolar bud site selection pattern in Saccharomyces cerevisiae.

P39965	SYPM_YEAST	Probable prolyl-tRNA synthetase, mitochondrial	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Q38954	PHT21_ARATH	Inorganic phosphate transporter 2-1, chloroplastic	12766230	Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.

P50123	AMPE_RAT	Glutamyl aminopeptidase	10978538	Molecular cloning and expression of aminopeptidase A isoforms from rat hippocampus.

P70539	ACV1C_RAT	Activin receptor type-1C	8875430	Molecular cloning of a novel type I receptor serine/threonine kinase for the TGF beta superfamily from rat brain.

Q9BQ15	SOSB1_HUMAN	SOSS complex subunit B1	19605351	hSSB1 and hSSB2 form similar multiprotein complexes that participate in DNA damage response.

P53196	RPN14_YEAST	26S proteasome regulatory subunit RPN14	19412159	Chaperone-mediated pathway of proteasome regulatory particle assembly.

P21399	ACOC_HUMAN	Cytoplasmic aconitate hydratase	16407072	Crystal structure of human iron regulatory protein 1 as cytosolic aconitase.

Q08969	GRE1_YEAST	Protein GRE1	14562095	Global analysis of protein localization in budding yeast.

O42928	YBD4_SCHPO	Uncharacterized protein C16C6.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9ZNV9	AHP1_ARATH	Histidine-containing phosphotransfer protein 1	10050311	Histidine-containing phosphotransfer (HPt) signal transducers implicated in His-to-Asp phosphorelay in Arabidopsis.

Q9SCZ4	FERON_ARATH	Receptor-like protein kinase FERONIA	17673660	The FERONIA receptor-like kinase mediates male-female interactions during pollen tube reception.

P35354	PGH2_HUMAN	Prostaglandin G/H synthase 2	1380156	Human cyclooxygenase-2 cDNA.

P38182	ATG8_YEAST	Autophagy-related protein 8	10837468	Aut7p, a soluble autophagic factor, participates in multiple membrane trafficking processes.

P22265	TSH_DROME	Protein teashirt	7607071	Role of the teashirt gene in Drosophila midgut morphogenesis: secreted proteins mediate the action of homeotic genes.

Q9BW71	HIRP3_HUMAN	HIRA-interacting protein 3	17391060	HIRIP3 is a nuclear phosphoprotein interacting with and phosphorylated by the serine-threonine kinase CK2.

P27590	UROM_RAT	Uromodulin	1531535	GP-2/THP gene family encodes self-binding glycosylphosphatidylinositol-anchored proteins in apical secretory compartments of pancreas and kidney.

P32899	IMP3_YEAST	U3 small nucleolar ribonucleoprotein protein IMP3	12068309	A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis.

P21217	FUT3_HUMAN	Galactoside 3(4)-L-fucosyltransferase	1977660	A cloned human cDNA determines expression of a mouse stage-specific embryonic antigen and the Lewis blood group alpha(1,3/1,4)fucosyltransferase.

Q08904	RDR1_YEAST	Protein RDR1	11882665	Zinc cluster protein Rdr1p is a transcriptional repressor of the PDR5 gene encoding a multidrug transporter.

P07713	DECA_DROME	Protein decapentaplegic	15867930	Dpp gets in shape.

P22355	PSPB_RAT	Pulmonary surfactant-associated protein B	2920185	cDNA and deduced amino acid sequence for the rat hydrophobic pulmonary surfactant-associated protein, SP-B.

P21461	SINA_DROME	E3 ubiquitin-protein ligase sina	2146028	Seven in absentia, a gene required for specification of R7 cell fate in the Drosophila eye.

Q93XK2	STSYN_PEA	Stachyose synthase	11675396	Chain elongation of raffinose in pea seeds. Isolation, characterization, and molecular cloning of a multifunctional enzyme catalyzing the synthesis of stachyose and verbascose.

Q14353	GAMT_HUMAN	Guanidinoacetate N-methyltransferase	8651275	Guanidinoacetate methyltransferase deficiency: the first inborn error of creatine metabolism in man.

P01714	LV301_HUMAN	Ig lambda chain V-III region SH	4909564	The amino acid sequence of a lambda type Bence-Jones protein. 3. The complete amino acid sequence and the location of the disulfide bridges.

Q9SFC6	GDIR_ARATH	Rho GDP-dissociation inhibitor 1	10798620	Localization of AtROP4 and AtROP6 and interaction with the guanine nucleotide dissociation inhibitor AtRhoGDI1 from Arabidopsis.

Q14204	DYHC1_HUMAN	Cytoplasmic dynein 1 heavy chain 1	8666668	Mammalian cells express three distinct dynein heavy chains that are localized to different cytoplasmic organelles.

Q6R1L1	TAF7_CRIGR	Transcription initiation factor TFIID subunit 7	15078871	TATA-binding protein-associated factor 7 regulates polyamine transport activity and polyamine analog-induced apoptosis.

Q9Y5S8	NOX1_HUMAN	NADPH oxidase 1	16636067	Nox1-dependent reactive oxygen generation is regulated by Rac1.

P08582	TRFM_HUMAN	Melanotransferrin	2419904	Primary structure of the human melanoma-associated antigen p97 (melanotransferrin) deduced from the mRNA sequence.

P53294	PUS6_YEAST	Pseudouridylate synthase 6	11406626	Identification and characterization of the tRNA:Psi 31-synthase (Pus6p) of Saccharomyces cerevisiae.

Q12083	MLH3_YEAST	DNA mismatch repair protein MLH3	10679328	Discrete in vivo roles for the MutL homologs Mlh2p and Mlh3p in the removal of frameshift intermediates in budding yeast.

Q12092	ATG29_YEAST	Autophagy-related protein 29	16289106	Characterization of a novel autophagy-specific gene, ATG29.

P15328	FOLR1_HUMAN	Folate receptor alpha	2768245	Molecular cloning and characterization of the human folate-binding protein cDNA from placenta and malignant tissue culture (KB) cells.

P28492	GLSL_RAT	Glutaminase liver isoform, mitochondrial	9164856	Rat hepatic glutaminase: identification of the full coding sequence and characterization of a functional promoter.

Q9V3I5	JIL1_DROME	Chromosomal serine/threonine-protein kinase JIL-1	11371341	The JIL-1 tandem kinase mediates histone H3 phosphorylation and is required for maintenance of chromatin structure in Drosophila.

Q8NBP7	PCSK9_HUMAN	Proprotein convertase subtilisin/kexin type 9	12552133	The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation.

P15941	MUC1_HUMAN	Mucin-1	1697589	Molecular cloning and expression of human tumor-associated polymorphic epithelial mucin.

P29317	EPHA2_HUMAN	Ephrin type-A receptor 2	18339848	EphA2 is an essential mediator of UV radiation-induced apoptosis.

P87053	POF1_SCHPO	F-box/WD repeat-containing protein pof1	15660136	SCF(Pof1)-ubiquitin and its target Zip1 transcription factor mediate cadmium response in fission yeast.

P21269	CCA1_YEAST	tRNA nucleotidyltransferase, mitochondrial	8175766	Interplay of heterogeneous transcriptional start sites and translational selection of AUGs dictate the production of mitochondrial and cytosolic/nuclear tRNA nucleotidyltransferase from the same gene in yeast.

P61966	AP1S1_HUMAN	AP-1 complex subunit sigma-1A	16548883	Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection.

Q9BRB3	PIGQ_HUMAN	Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q	9729469	Human and mouse Gpi1p homologues restore glycosylphosphatidylinositol membrane anchor biosynthesis in yeast mutants.

P43080	GUC1A_HUMAN	Guanylyl cyclase-activating protein 1	9425234	A mutation in guanylate cyclase activator 1A (GUCA1A) in an autosomal dominant cone dystrophy pedigree mapping to a new locus on chromosome 6p21.1.

Q9JIF0	ANM1_MOUSE	Protein arginine N-methyltransferase 1	10848611	Arginine N-methyltransferase 1 is required for early postimplantation mouse development, but cells deficient in the enzyme are viable.

P12815	PDCD6_MOUSE	Programmed cell death protein 6	10200558	Alix, a novel mouse protein undergoing calcium-dependent interaction with the apoptotsis-linked-gene 2 (ALG-2) protein.

Q13936	CAC1C_HUMAN	Voltage-dependent L-type calcium channel subunit alpha-1C	15140941	Ca2+-binding protein-1 facilitates and forms a postsynaptic complex with Cav1.2 (L-type) Ca2+ channels.

P91870	SPD2_CAEEL	Spindle-defective protein 2	15186742	The Caenorhabditis elegans centrosomal protein SPD-2 is required for both pericentriolar material recruitment and centriole duplication.

P38851	YSP1_YEAST	Protein YSP1	15657396	Role of mitochondria in the pheromone- and amiodarone-induced programmed death of yeast.

P61457	PHS_HUMAN	Pterin-4-alpha-carbinolamine dehydratase	1763325	Characterization of a cofactor that regulates dimerization of a mammalian homeodomain protein.

Q9P1U0	RPA12_HUMAN	DNA-directed RNA polymerase I subunit RPA12	10662553	A new zinc ribbon gene (ZNRD1) is cloned from the human MHC class I region.

Q9P4X3	UTP7_SCHPO	Probable U3 small nucleolar RNA-associated protein 7	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9QYE3	BC11A_MOUSE	B-cell lymphoma/leukemia 11A	12717432	Bcl11a is essential for normal lymphoid development.

Q06143	DIC1_YEAST	Mitochondrial dicarboxylate transporter	9559855	Bacterial overexpression of putative yeast mitochondrial transport proteins.

Q8LGH4	CUL4_ARATH	Cullin-4	18552200	Arabidopsis DDB1-CUL4 ASSOCIATED FACTOR1 forms a nuclear E3 ubiquitin ligase with DDB1 and CUL4 that is involved in multiple plant developmental processes.

Q9ZUX7	IPT2_ARATH	tRNA dimethylallyltransferase 2	11313355	Identification of genes encoding adenylate isopentenyltransferase, a cytokinin biosynthesis enzyme, in Arabidopsis thaliana.

Q96Q15	SMG1_HUMAN	Serine/threonine-protein kinase SMG1	19417104	SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay.

Q9SP32	DICER_ARATH	Endoribonuclease Dicer homolog	10556049	Disruption of an RNA helicase/RNase III gene in Arabidopsis causes unregulated cell division in floral meristems.

P27351	AP2B_YEAST	AP-2 complex subunit beta	10564262	Adaptor complex-independent clathrin function in yeast.

Q8TB72	PUM2_HUMAN	Pumilio homolog 2	12511597	Human Pumilio-2 is expressed in embryonic stem cells and germ cells and interacts with DAZ (Deleted in AZoospermia) and DAZ-like proteins.

Q5T6F0	DCA12_HUMAN	DDB1- and CUL4-associated factor 12	16949367	A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1.

Q03161	YMY9_YEAST	Glucose-6-phosphate 1-epimerase	16857670	Structure-based functional annotation: yeast ymr099c codes for a D- hexose-6-phosphate mutarotase.

Q9Y4J8	DTNA_HUMAN	Dystrobrevin alpha	8845841	Cloning and characterization of the human homologue of a dystrophin related phosphoprotein found at the Torpedo electric organ post- synaptic membrane.

P14922	CYC8_YEAST	General transcriptional corepressor CYC8	10722672	Hrs1/Med3 is a Cyc8-Tup1 corepressor target in the RNA polymerase II holoenzyme.

P32861	UGPA1_YEAST	UTP--glucose-1-phosphate uridylyltransferase	7588797	Genetic and biochemical characterization of the UGP1 gene encoding the UDP-glucose pyrophosphorylase from Saccharomyces cerevisiae.

Q8JIT6	FOXB2_XENLA	Forkhead box protein B2	15656969	Of fox and frogs: fox (fork head/winged helix) transcription factors in Xenopus development.

O59704	ELP1_SCHPO	Elongator complex protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P49893	WN11B_XENLA	Protein Wnt-11b	19747829	Wnt11/5a complex formation caused by tyrosine sulfation increases canonical signaling activity.

Q7T3Y0	NARPA_DANRE	Notch-regulated ankyrin repeat-containing protein A	16228014	Nrarp functions to modulate neural-crest-cell differentiation by regulating LEF1 protein stability.

O43683	BUB1_HUMAN	Mitotic checkpoint serine/threonine-protein kinase BUB1	15020684	Bub1 is required for kinetochore localization of BubR1, Cenp-E, Cenp- F and Mad2, and chromosome congression.

P35193	ATG19_YEAST	Autophagy-related protein 19	12479808	Mechanism of cargo selection in the cytoplasm to vacuole targeting pathway.

Q99N48	SYTL3_MOUSE	Synaptotagmin-like protein 3	11243866	Synaptotagmin-like protein 1-3: a novel family of C-terminal-type tandem C2 proteins.

Q78P75	DYL2_RAT	Dynein light chain 2, cytoplasmic	12097491	Gephyrin interacts with dynein light chains 1 and 2, components of motor protein complexes.

Q13043	STK4_HUMAN	Serine/threonine-protein kinase 4	8702870	The Ste20-like protein kinase, Mst1, dimerizes and contains an inhibitory domain.

Q9BW19	KIFC1_HUMAN	Kinesin-like protein KIFC1	8276466	Cloning of a new kinesin-related gene located at the centromeric end of the human MHC region.

P13349	MYF5_HUMAN	Myogenic factor 5	2721498	A novel human muscle factor related to but distinct from MyoD1 induces myogenic conversion in 10T1/2 fibroblasts.

P15531	NDKA_HUMAN	Nucleoside diphosphate kinase A	12972261	Nucleotide binding to nucleoside diphosphate kinases: X-ray structure of human NDPK-A in complex with ADP and comparison to protein kinases.

O42261	IRX3_XENLA	Iroquois-class homeodomain protein irx-3	12385755	Xiro homeoproteins coordinate cell cycle exit and primary neuron formation by upregulating neuronal-fate repressors and downregulating the cell-cycle inhibitor XGadd45-gamma.

P69850	DAD3_YEAST	DASH complex subunit DAD3	12408861	Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase Ipl1p.

P30793	GCH1_HUMAN	GTP cyclohydrolase 1	9445252	Cytokines stimulate GTP cyclohydrolase I gene expression in cultured human umbilical vein endothelial cells.

P48239	GTO1_YEAST	Glutathione S-transferase omega-like 1	16709151	Saccharomyces cerevisiae cells have three Omega class glutathione S- transferases acting as 1-Cys thiol transferases.

Q62755	NR1H2_RAT	Oxysterols receptor LXR-beta	7892230	OR-1, a member of the nuclear receptor superfamily that interacts with the 9-cis-retinoic acid receptor.

O13981	YEK7_SCHPO	UFP0650 endoplasmic reticulum membrane protein C25H1.07	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O55145	X3CL1_RAT	Fractalkine	9724801	Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia.

P50406	5HT6R_HUMAN	5-hydroxytryptamine receptor 6	8522988	Cloning, characterization, and chromosomal localization of a human 5- HT6 serotonin receptor.

P31785	IL2RG_HUMAN	Cytokine receptor common subunit gamma	8266078	Interleukin-2 receptor gamma chain: a functional component of the interleukin-4 receptor.

Q6P9R2	OXSR1_MOUSE	Serine/threonine-protein kinase OSR1	12386165	Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1).

Q9BQA1	MEP50_HUMAN	Methylosome protein 50	16087681	Toward an assembly line for U7 snRNPs: interactions of U7-specific Lsm proteins with PRMT5 and SMN complexes.

Q12287	COX17_YEAST	Cytochrome c oxidase copper chaperone	9585572	Characterization of the copper chaperone Cox17 of Saccharomyces cerevisiae.

Q9ET47	ESPN_MOUSE	Espin	10975527	The deaf jerker mouse has a mutation in the gene encoding the espin actin-bundling proteins of hair cell stereocilia and lacks espins.

Q05030	PGFRB_RAT	Beta-type platelet-derived growth factor receptor	8318539	Conservation in sequence and affinity of human and rodent PDGF ligands and receptors.

O75909	CCNK_HUMAN	Cyclin-K	9632813	Human cyclin K, a novel RNA polymerase II-associated cyclin possessing both carboxy-terminal domain kinase and Cdk-activating kinase activity.

Q96PU4	UHRF2_HUMAN	E3 ubiquitin-protein ligase UHRF2	12176013	NIRF, a novel RING finger protein, is involved in cell-cycle regulation.

Q805F7	DISA_AGKCO	Disintegrin acostatin-alpha	12450389	A new gene structure of the disintegrin family: a subunit of dimeric disintegrin has a short coding region.

O60187	SID4_SCHPO	Septation initiation protein sid4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q5BCC6	BGLC_EMENI	Beta-glucosidase C	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

P76577	PBPC_ECOLI	Penicillin-binding protein 1C	10542235	Cloning and characterization of PBP 1C, a third member of the multimodular class A penicillin-binding proteins of Escherichia coli.

O15392	BIRC5_HUMAN	Baculoviral IAP repeat-containing protein 5	9859993	Control of apoptosis and mitotic spindle checkpoint by survivin.

Q9BVI0	PHF20_HUMAN	PHD finger protein 20	15960975	Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

Q05958	ECM22_YEAST	Sterol regulatory element-binding protein ECM22	11533229	Upc2p and Ecm22p, dual regulators of sterol biosynthesis in Saccharomyces cerevisiae.

Q16667	CDKN3_HUMAN	Cyclin-dependent kinase inhibitor 3	8242750	Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2.

P76129	DOSP_ECOLI	Oxygen sensor protein DosP	14551206	Relationships between heme incorporation, tetramer formation, and catalysis of a heme-regulated phosphodiesterase from Escherichia coli: a study of deletion and site-directed mutants.

Q9UTM9	FAP2_SCHPO	L-saccharopine oxidase	16233628	Characterization of two fructosyl-amino acid oxidase homologs of Schizosaccharomyces pombe.

Q9NRT5	SMG64_HUMAN	Putative smooth muscle cell-expressed and macrophage conditioned medium-induced protein 64	10823842	Differential display identification of 40 genes with altered expression in activated human smooth muscle cells. Local expression in atherosclerotic lesions of smags, smooth muscle activation-specific genes.

Q8VZS8	PYL1_ARATH	Abscisic acid receptor PYL1	19407142	Abscisic acid inhibits type 2C protein phosphatases via the PYR/PYL family of START proteins.

Q92317	NCB2_YEAST	Negative cofactor 2 complex subunit beta	9096360	Functional antagonism between RNA polymerase II holoenzyme and global negative regulator NC2 in vivo.

Q96WW3	YNH5_SCHPO	UPF0642 protein C32H8.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P06804	TNFA_MOUSE	Tumor necrosis factor	3898078	Cloning and expression in Escherichia coli of the cDNA for murine tumor necrosis factor.

P87170	DGK1_SCHPO	CTP-dependent diacylglycerol kinase 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8R173	ZDHC3_MOUSE	Palmitoyltransferase ZDHHC3	12163046	Isolation and characterization of Golgi apparatus-specific GODZ with the DHHC zinc finger domain.

Q8IRY7	CASP8_DROME	Caspase-8	10934188	dFADD, a novel death domain-containing adapter protein for the Drosophila caspase DREDD.

Q9U297	KDM4_CAEEL	Lysine-specific demethylase 4	16603238	Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases.

Q9FJU9	E1313_ARATH	Glucan endo-1,3-beta-glucosidase 13	14517339	Proteomic analysis of glycosylphosphatidylinositol-anchored membrane proteins.

P63165	SUMO1_HUMAN	Small ubiquitin-related modifier 1	8812453	UBL1, a human ubiquitin-like protein associating with human RAD51/RAD52 proteins.

O75486	SUPT3_HUMAN	Transcription initiation protein SPT3 homolog	9787080	Characterization of a human homologue of the Saccharomyces cerevisiae transcription factor Spt3 (SUPT3H).

Q9Y6H5	SNCAP_HUMAN	Synphilin-1	11590439	Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease.

Q8IBB8	YPF15_PLAF7	Uncharacterized protein MAL8P1.12	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

Q14676	MDC1_HUMAN	Mediator of DNA damage checkpoint protein 1	12607003	MDC1 is required for the intra-S-phase DNA damage checkpoint.

P39904	VPS52_YEAST	Vacuolar protein sorting-associated protein 52	12377769	Vps51p links the VFT complex to the SNARE Tlg1p.

P81274	GPSM2_HUMAN	G-protein-signaling modulator 2	8973305	Identification and cDNA cloning of a novel human mosaic protein, LGN, based on interaction with G alpha i2.

P05230	FGF1_HUMAN	Heparin-binding growth factor 1	10830168	Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity.

O02372	OB76A_DROME	General odorant-binding protein lush	11238251	The invertebrate odorant-binding protein LUSH is required for normal olfactory behavior in Drosophila.

O77459	KEN_DROME	Transcription factor Ken	16401426	Ken & barbie selectively regulates the expression of a subset of Jak/STAT pathway target genes.

P62491	RB11A_HUMAN	Ras-related protein Rab-11A	17030804	Structural basis for Rab11-dependent membrane recruitment of a family of Rab11-interacting protein 3 (FIP3)/Arfophilin-1.

O43663	PRC1_HUMAN	Protein regulator of cytokinesis 1	14744859	Human mitotic spindle-associated protein PRC1 inhibits MgcRacGAP activity toward Cdc42 during the metaphase.

P32598	PP12_YEAST	Serine/threonine-protein phosphatase PP1-2	1660885	The yeast GLC7 gene required for glycogen accumulation encodes a type 1 protein phosphatase.

P22492	H1T_HUMAN	Histone H1t	1889752	Structure and expression of the human gene encoding testicular H1 histone (H1t).

P18509	PACA_HUMAN	Pituitary adenylate cyclase-activating polypeptide	2302217	A novel peptide which stimulates adenylate cyclase: molecular cloning and characterization of the ovine and human cDNAs.

Q9WUS4	CXA10_MOUSE	Gap junction alpha-10 protein	16820008	Horizontal cell receptive fields are reduced in connexin57-deficient mice.

P17200	ACM4_CHICK	Muscarinic acetylcholine receptor M4	2154460	Cloning and functional analysis of a gene encoding a novel muscarinic acetylcholine receptor expressed in chick heart and brain.

Q14511	CASL_HUMAN	Enhancer of filamentation 1	11827972	MICAL, a novel CasL interacting molecule, associates with vimentin.

Q9NZI7	UBIP1_HUMAN	Upstream-binding protein 1	8114710	Characterization of a family of related cellular transcription factors which can modulate human immunodeficiency virus type 1 transcription in vitro.

P10243	MYBA_HUMAN	Myb-related protein A	8058310	The human A-myb protein is a strong activator of transcription.

Q96291	BAS1A_ARATH	2-Cys peroxiredoxin BAS1, chloroplastic	12529539	Divergent light-, ascorbate-, and oxidative stress-dependent regulation of expression of the peroxiredoxin gene family in Arabidopsis.

Q71S46	AT5G3_RAT	ATP synthase lipid-binding protein, mitochondrial	11459924	Rat mitochondrial ATP synthase ATP5G3: cloning and upregulation in pancreas after chronic ethanol feeding.

P36382	CXA5_HUMAN	Gap junction alpha-5 protein	7966354	Molecular cloning of two human cardiac gap junction proteins, connexin40 and connexin45.

O95997	PTTG1_HUMAN	Securin	9811450	hPTTG, a human homologue of rat PTTG, is overexpressed in hematopoietic neoplasms. Evidence for a transcriptional activation function of hPTTG.

Q925D8	TS1R3_MOUSE	Taste receptor type 1 member 3	11555487	Positional cloning of the mouse saccharin preference (Sac) locus.

Q03956	RAV2_YEAST	Regulator of V-ATPase in vacuolar membrane protein 2	11844802	The RAVE complex is essential for stable assembly of the yeast V- ATPase.

Q9JLB0	MPP6_MOUSE	MAGUK p55 subfamily member 6	10753959	Molecular cloning and characterization of Pals, proteins associated with mLin-7.

O43114	ORC5_SCHPO	Origin recognition complex subunit 5	11850415	Purification and characterization of the Schizosaccharomyces pombe origin recognition complex: interaction with origin DNA and Cdc18 protein.

P07199	CENPB_HUMAN	Major centromere autoantigen B	1893793	CENP-B is a highly conserved mammalian centromere protein with homology to the helix-loop-helix family of proteins.

Q03921	DOP1_YEAST	Protein dopey	16301316	Mon2, a relative of large Arf exchange factors, recruits Dop1 to the Golgi apparatus.

P06870	KLK1_HUMAN	Kallikrein-1	7749372	Molecular cloning and characterization of a novel kallikrein transcript in colon and its distribution in human tissues.

Q04930	CRF1_YEAST	Transcription factor CRF1	15620355	TOR regulates ribosomal protein gene expression via PKA and the forkhead transcription factor FHL1.

Q3UDK1	TRAD1_MOUSE	TRAF-type zinc finger domain-containing protein 1	18849341	FLN29 deficiency reveals its negative regulatory role in the Toll- like receptor (TLR) and retinoic acid-inducible gene I (RIG-I)-like helicase signaling pathway.

Q03834	MSH6_YEAST	DNA mismatch repair protein MSH6	9545323	ATP-dependent assembly of a ternary complex consisting of a DNA mismatch and the yeast MSH2-MSH6 and MLH1-PMS1 protein complexes.

Q9LTB8	CNBL9_ARATH	Calcineurin B-like protein 9	17898163	A protein phosphorylation/dephosphorylation network regulates a plant potassium channel.

Q9UHN6	TMEM2_HUMAN	Transmembrane protein 2	10767548	Refining the DFNB7-DFNB11 deafness locus using intragenic polymorphisms in a novel gene, TMEM2.

Q06278	ADO_HUMAN	Aldehyde oxidase	8248161	cDNA cloning, characterization, and tissue-specific expression of human xanthine dehydrogenase/xanthine oxidase.

Q9P6K8	YLF3_SCHPO	Uncharacterized protein C30C2.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12018	CDC53_YEAST	Cell division control protein 53	10385629	Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34.

P28908	TNR8_HUMAN	Tumor necrosis factor receptor superfamily member 8	8627180	T cell receptor-dependent cell death of T cell hybridomas mediated by the CD30 cytoplasmic domain in association with tumor necrosis factor receptor-associated factors.

Q9FJ54	CIPKK_ARATH	CBL-interacting serine/threonine-protein kinase 20	12198122	Constitutive activation and transgenic evaluation of the function of an arabidopsis PKS protein kinase.

O16850	FOXO_CAEEL	Forkhead box protein O	11747821	Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway.

P97884	CCL20_RAT	C-C motif chemokine 20	9916893	A novel rat CC chemokine, identified by targeted differential display, is upregulated in brain inflammation.

Q9VXG1	HANG_DROME	Zinc finger protein hangover	16094367	The hangover gene defines a stress pathway required for ethanol tolerance development.

O00559	RCAS1_HUMAN	Receptor-binding cancer antigen expressed on SiSo cells	10426319	Inhibition of cell growth and induction of apoptotic cell death by the human tumor-associated antigen RCAS1.

B0F9L4	GOGC6_ARATH	Golgin candidate 6	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

Q09702	NRD1_SCHPO	Negative regulator of differentiation 1	9671458	An RNA binding protein negatively controlling differentiation in fission yeast.

Q5FWP4	CHFR_XENLA	E3 ubiquitin-protein ligase CHFR	15467728	PML bodies control the nuclear dynamics and function of the CHFR mitotic checkpoint protein.

Q16666	IF16_HUMAN	Gamma-interferon-inducible protein 16	9766636	The IFN-inducible nucleoprotein IFI 16 is expressed in cells of the monocyte lineage, but is rapidly and markedly down-regulated in other myeloid precursor populations.

O95340	PAPS2_HUMAN	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2	9771708	Mutations in orthologous genes in human spondyloepimetaphyseal dysplasia and the brachymorphic mouse.

P84554	TIQ2_RHISA	Kunitz-type serine protease inhibitor RsTIQ2	12941299	Rhipicephalus sanguineus trypsin inhibitors present in the tick larvae: isolation, characterization, and partial primary structure determination.

Q9HAU5	RENT2_HUMAN	Regulator of nonsense transcripts 2	11544179	Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay.

Q9ERI2	RB27A_MOUSE	Ras-related protein Rab-27A	18266782	Slp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapse.

Q924K8	MTA3_MOUSE	Metastasis-associated protein MTA3	11483358	Differential expression and subcellular distribution of the mouse metastasis-associated proteins Mta1 and Mta3.

O81108	ACA2_ARATH	Calcium-transporting ATPase 2, plasma membrane-type	10823962	A calcium-dependent protein kinase can inhibit a calmodulin- stimulated Ca2+ pump (ACA2) located in the endoplasmic reticulum of Arabidopsis.

P32561	RPD3_YEAST	Histone deacetylase RPD3	11069890	Ssn6-Tup1 interacts with class I histone deacetylases required for repression.

Q07817	B2CL1_HUMAN	Bcl-2-like protein 1	8358789	bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death.

P28037	FTHFD_RAT	10-formyltetrahydrofolate dehydrogenase	1848231	Isolation and characterization of cDNA clones for rat liver 10- formyltetrahydrofolate dehydrogenase.

Q00341	VIGLN_HUMAN	Vigilin	1318310	Cloning and expression of a cellular high density lipoprotein-binding protein that is up-regulated by cholesterol loading of cells.

Q6R327	RICTR_HUMAN	Rapamycin-insensitive companion of mTOR	15467718	Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive.

Q61301	CTNA2_MOUSE	Catenin alpha-2	16457793	Differential expression of alpha-E-catenin and alpha-N-catenin in the developing cerebral cortex.

P31230	AIMP1_MOUSE	Aminoacyl tRNA synthase complex-interacting multifunctional protein 1	11306575	The EMAPII cytokine is released from the mammalian multisynthetase complex after cleavage of its p43/proEMAPII component.

P0AA43	RSUA_ECOLI	Ribosomal small subunit pseudouridine synthase A	7612632	Purification, cloning, and properties of the 16S RNA pseudouridine 516 synthase from Escherichia coli.

Q24139	COMM_DROME	Protein commissureless	8785048	Commissureless controls growth cone guidance across the CNS midline in Drosophila and encodes a novel membrane protein.

P57679	EVC_HUMAN	Ellis-van Creveld syndrome protein	10700184	Mutations in a new gene in Ellis-van Creveld syndrome and Weyers acrodental dysostosis.

O14077	MU138_SCHPO	Putative zinc protease mug138	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q0WNX9	KRP6_ARATH	Cyclin-dependent kinase inhibitor 6	18552199	Targeted degradation of the cyclin-dependent kinase inhibitor ICK4/KRP6 by RING-type E3 ligases is essential for mitotic cell cycle progression during Arabidopsis gametogenesis.

Q08229	NBA1_YEAST	Protein NBA1	16702403	Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes.

Q03162	MUB1_YEAST	MYND-type zinc finger protein MUB1	9427754	Integrity of a Zn finger-like domain in SamB is crucial for morphogenesis in ascomycetous fungi.

Q05201	EYA_DROME	Developmental protein eyes absent	8431945	The eyes absent gene: genetic control of cell survival and differentiation in the developing Drosophila eye.

P39690	KHS1_YEAST	Killer toxin KHS	1368726	Cloning and nucleotide sequence of the KHS killer gene of Saccharomyces cerevisiae.

P84853	RIPL1_PHYDI	Ribosome-inactivating protein PD-L1/PD-L2	10213004	Isolation and characterization of four type-1 ribosome-inactivating proteins, with polynucleotide:adenosine glycosidase activity, from leaves of Phytolacca dioica L.

Q9VQU9	BOWEL_DROME	Protein bowel	11784087	Drumstick, bowl, and lines are required for patterning and cell rearrangement in the Drosophila embryonic hindgut.

Q23973	MTRM_DROME	Protein matrimony	14573476	A deficiency screen of the major autosomes identifies a gene (matrimony) that is haplo-insufficient for achiasmate segregation in Drosophila oocytes.

P28340	DPOD1_HUMAN	DNA polymerase delta catalytic subunit	16510448	Functional roles of p12, the fourth subunit of human DNA polymerase delta.

Q15386	UBE3C_HUMAN	Ubiquitin-protein ligase E3C	11278995	A HECT domain E3 enzyme assembles novel polyubiquitin chains.

P21730	C5AR_HUMAN	C5a anaphylatoxin chemotactic receptor	1847994	The chemotactic receptor for human C5a anaphylatoxin.

P49731	MCM6_SCHPO	DNA replication licensing factor mcm6	12006645	SpSld3 is required for loading and maintenance of SpCdc45 on chromatin in DNA replication in fission yeast.

Q9UBC5	MYO1A_HUMAN	Myosin-Ia	9858156	Human brush border myosin-I and myosin-Ic expression in human intestine and Caco-2BBe cells.

Q10953	WRM1_CAEEL	Armadillo repeat-containing protein wrm-1	10380924	WRM-1 activates the LIT-1 protein kinase to transduce anterior/posterior polarity signals in C. elegans.

O48721	HEM4_ARATH	Uroporphyrinogen-III synthase, chloroplastic	18042043	Identification and characterization of the Arabidopsis gene encoding the tetrapyrrole biosynthesis enzyme uroporphyrinogen III synthase.

Q9FZ33	AXR4_ARATH	Protein AUXIN RESPONSE 4	16690816	AXR4 is required for localization of the auxin influx facilitator AUX1.

Q17941	AKT1_CAEEL	Serine/threonine-protein kinase akt-1	15068796	C. elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span.

P50237	ST1C1_RAT	Sulfotransferase 1C1	8227031	Isolation and expression of a cDNA encoding a male-specific rat sulfotransferase that catalyzes activation of N-hydroxy-2- acetylaminofluorene.

P02751	FINC_HUMAN	Fibronectin	11956183	The type XIII collagen ectodomain is a 150-nm rod and capable of binding to fibronectin, nidogen-2, perlecan, and heparin.

Q07953	SDO1_YEAST	Ribosome maturation protein SDO1	14562095	Global analysis of protein localization in budding yeast.

P30429	CED4_CAEEL	Cell death protein 4	9027313	Interaction and regulation of subcellular localization of CED-4 by CED-9.

P18852	GBG_YEAST	Guanine nucleotide-binding protein subunit gamma	10749875	Functional analysis of Plp1 and Plp2, two homologues of phosducin in yeast.

C0LGQ5	GSO1_ARATH	LRR receptor-like serine/threonine-protein kinase GSO1	18088309	GASSHO1 and GASSHO2 encoding a putative leucine-rich repeat transmembrane-type receptor kinase are essential for the normal development of the epidermal surface in Arabidopsis embryos.

Q13541	4EBP1_HUMAN	Eukaryotic translation initiation factor 4E-binding protein 1	12150926	Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action.

P28064	PSB8_RAT	Proteasome subunit beta type-8	1451788	cDNA cloning of rat proteasome subunit RC1, a homologue of RING10 located in the human MHC class II region.

O88393	TGBR3_MOUSE	Transforming growth factor beta receptor type 3	9659379	Murine betaglycan primary structure, expression and glycosaminoglycan attachment sites.

Q9VZF4	FBXW7_DROME	F-box/WD repeat-containing protein 7	15182669	The Drosophila F box protein archipelago regulates dMyc protein levels in vivo.

O00499	BIN1_HUMAN	Myc box-dependent-interacting protein 1	8782822	BIN1 is a novel Myc-interacting protein with features of a tumour suppressor.

P97523	MET_RAT	Hepatocyte growth factor receptor	8853431	Primary structure of rat HGF receptor and induced expression in glomerular mesangial cells.

Q13523	PRP4B_HUMAN	Serine/threonine-protein kinase PRP4 homolog	9102632	Functional analysis of the fission yeast Prp4 protein kinase involved in pre-mRNA splicing and isolation of a putative mammalian homologue.

P84692	SC64_TITCA	Toxin Tc64	15025998	Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

Q8S8Y9	WNK2_ARATH	Serine/threonine-protein kinase WNK2	18761494	The plant WNK gene family and regulation of flowering time in Arabidopsis.

Q54HT1	TIRA_DICDI	Protein tirA	17673666	Immune-like phagocyte activity in the social amoeba.

Q84JK2	FD_ARATH	Protein FD	16099980	Integration of spatial and temporal information during floral induction in Arabidopsis.

P55196	AFAD_HUMAN	Afadin	8242616	Cloning of the ALL-1 fusion partner, the AF-6 gene, involved in acute myeloid leukemias with the t(6;11) chromosome translocation.

P61626	LYSC_HUMAN	Lysozyme C	2829884	Human lysozyme: sequencing of a cDNA, and expression and secretion by Saccharomyces cerevisiae.

Q8WZA2	RPGF4_HUMAN	Rap guanine nucleotide exchange factor 4	10777494	Mechanism of regulation of the Epac family of cAMP-dependent RapGEFs.

P38692	KIC1_YEAST	Serine/threonine-protein kinase KIC1	9813095	The yeast centrin, cdc31p, and the interacting protein kinase, Kic1p, are required for cell integrity.

P07236	SYTM_YEAST	Threonyl-tRNA synthetase, mitochondrial	2999113	Characterization of a yeast nuclear gene (MST1) coding for the mitochondrial threonyl-tRNA1 synthetase.

Q9Y7V0	MU117_SCHPO	Meiotically up-regulated gene 117 protein	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

P83627	VIH_ARMVU	Vitellogenesis-inhibiting hormone	10480992	Isolation and amino acid sequence of a peptide with vitellogenesis inhibiting activity from the terrestrial isopod Armadillidium vulgare (Crustacea).

O14192	AATR1_SCHPO	Aromatic amino acid aminotransferase C56E4.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P29317	EPHA2_HUMAN	Ephrin type-A receptor 2	18794797	Soluble monomeric EphrinA1 is released from tumor cells and is a functional ligand for the EphA2 receptor.

O97581	LHX3_PIG	LIM/homeobox protein Lhx3	10195693	Characterization of the porcine Lhx3/LIM-3/P-Lim LIM homeodomain transcription factor.

Q6ZRS2	SRCAP_HUMAN	Helicase SRCAP	14966270	Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans.

Q23FE2	TTL3C_TETTH	Tubulin glycylase 3C	19531357	TTLL3 Is a tubulin glycine ligase that regulates the assembly of cilia.

Q60932	VDAC1_MOUSE	Voltage-dependent anion-selective channel protein 1	18988731	The crystal structure of mouse VDAC1 at 2.3 A resolution reveals mechanistic insights into metabolite gating.

Q7TN44	MRGB5_RAT	Mas-related G-protein coupled receptor member B5	12909716	Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family.

O43809	CPSF5_HUMAN	Cleavage and polyadenylation specificity factor subunit 5	14561889	Association of polyadenylation cleavage factor I with U1 snRNP.

O15318	RPC7_HUMAN	DNA-directed RNA polymerase III subunit RPC7	19609254	RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate.

Q08457	YO060_YEAST	Mitochondrial morphogenesis protein YOR060C	16135527	Role of essential genes in mitochondrial morphogenesis in Saccharomyces cerevisiae.

Q55BV5	PRS4_DICDI	26S protease regulatory subunit 4 homolog	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

O55164	MPDZ_RAT	Multiple PDZ domain protein	9537516	Cloning and characterization of MUPP1, a novel PDZ domain protein.

Q9JKM7	RAB37_MOUSE	Ras-related protein Rab-37	10722846	Rab37 is a novel mast cell specific GTPase localized to secretory granules.

Q9FRI0	MEE8_ARATH	Transcription factor MEE8	15634699	Genetic and molecular identification of genes required for female gametophyte development and function in Arabidopsis.

O22190	GH33_ARATH	Indole-3-acetic acid-amido synthetase GH3.3	15659623	Characterization of an Arabidopsis enzyme family that conjugates amino acids to indole-3-acetic acid.

P23378	GCSP_HUMAN	Glycine dehydrogenase [decarboxylating], mitochondrial	1996985	Structural and expression analyses of normal and mutant mRNA encoding glycine decarboxylase: three-base deletion in mRNA causes nonketotic hyperglycinemia.

Q3V6T2	GRDN_HUMAN	Girdin	15882442	A novel hook-related protein family and the characterization of hook- related protein 1.

Q8CFH6	SIK2_MOUSE	Serine/threonine-protein kinase SIK2	12624099	Adipose-specific expression, phosphorylation of Ser794 in insulin receptor substrate-1, and activation in diabetic animals of salt- inducible kinase-2.

Q17335	ADHX_CAEEL	Alcohol dehydrogenase class-3	7608988	Caenorhabditis elegans contains genes encoding two new members of the Zn-containing alcohol dehydrogenase family.

Q9NDC9	LIS1_CAEEL	Lissencephaly-1 homolog	15331665	lis-1 is required for dynein-dependent cell division processes in C. elegans embryos.

P38234	RFS1_YEAST	Protein RFS1	14562095	Global analysis of protein localization in budding yeast.

Q9JK95	PERP_MOUSE	p53 apoptosis effector related to PMP-22	10733530	PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family.

Q9C9Y6	TRXH9_ARATH	Thioredoxin H9	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

P16104	H2AX_HUMAN	Histone H2A.x	16820410	Novel function of beta-arrestin2 in the nucleus of mature spermatozoa.

Q9UN67	PCDBA_HUMAN	Protocadherin beta-10	11322959	The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number.

P08646	RAS1_DROME	Ras-like protein 1	18503409	Regulation of a Drosophila melanogaster cGMP-specific phosphodiesterase by prenylation and interaction with a prenyl-binding protein.

P60900	PSA6_HUMAN	Proteasome subunit alpha type-6	1888762	The primary structures of four subunits of the human, high-molecular- weight proteinase, macropain (proteasome), are distinct but homologous.

P43246	MSH2_HUMAN	DNA mismatch repair protein Msh2	7923193	Purified human MSH2 protein binds to DNA containing mismatched nucleotides.

Q06667	IPK1_YEAST	Inositol-pentakisphosphate 2-kinase	10390371	A phospholipase C-dependent inositol polyphosphate kinase pathway required for efficient messenger RNA export.

P78362	SRPK2_HUMAN	Serine/threonine-protein kinase SRPK2	9472028	SRPK2: a differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells.

P06525	ADH1_ARATH	Alcohol dehydrogenase class-P	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

Q66K74	MAP1S_HUMAN	Microtubule-associated protein 1S	14627543	Identification and characterization of a VCY2 interacting protein-1; VCY2IP-1, a MAP-like protein.

Q1MTQ5	MUG89_SCHPO	Meiotically up-regulated gene 89 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q92953	KCNB2_HUMAN	Potassium voltage-gated channel subfamily B member 2	9612272	Molecular identification of a component of delayed rectifier current in gastrointestinal smooth muscles.

Q99260	YPT6_YEAST	GTP-binding protein YPT6	11943201	Identification of the novel proteins Yip4p and Yip5p as Rab GTPase interacting factors.

Q13469	NFAC2_HUMAN	Nuclear factor of activated T-cells, cytoplasmic 2	8668213	Recombinant NFAT1 (NFATp) is regulated by calcineurin in T cells and mediates transcription of several cytokine genes.

O13963	MVD1_SCHPO	Diphosphomevalonate decarboxylase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q5RJI4	PKDCC_MOUSE	Protein kinase domain-containing protein, cytoplasmic	19465597	The novel protein kinase Vlk is essential for stromal function of mesenchymal cells.

Q570C0	TIR1_ARATH	Protein TRANSPORT INHIBITOR RESPONSE 1	14617065	Regulation of Arabidopsis SHY2/IAA3 protein turnover.

Q54JE1	SIBB_DICDI	Integrin beta-like protein B	16699495	An adhesion molecule in free-living Dictyostelium amoebae with integrin beta features.

Q9NS61	KCIP2_HUMAN	Kv channel-interacting protein 2	11287421	Conserved Kv4 N-terminal domain critical for effects of Kv channel- interacting protein 2.2 on channel expression and gating.

O60840	CAC1F_HUMAN	Voltage-dependent L-type calcium channel subunit alpha-1F	15897456	A CACNA1F mutation identified in an X-linked retinal disorder shifts the voltage dependence of Cav1.4 channel activation.

P63033	RHES_RAT	GTP-binding protein Rhes	14724584	The small GTP-binding protein, Rhes, regulates signal transduction from G protein-coupled receptors.

P54873	HMCS_ARATH	Hydroxymethylglutaryl-CoA synthase	8566777	Isolation and characterization of a cDNA encoding Arabidopsis thaliana 3-hydroxy-3-methylglutaryl-coenzyme A synthase.

Q05812	MSC3_YEAST	Meiotic sister-chromatid recombination protein 3	10511544	Genetic control of recombination partner preference in yeast meiosis. Isolation and characterization of mutants elevated for meiotic unequal sister-chromatid recombination.

P42124	EZ_DROME	Histone-lysine N-methyltransferase E(z)	12697833	A 1-megadalton ESC/E(Z) complex from Drosophila that contains polycomblike and RPD3.

P40240	CD9_MOUSE	CD9 antigen	11805154	Murine CD9 is the receptor for pregnancy-specific glycoprotein 17.

P56159	GFRA1_HUMAN	GDNF family receptor alpha-1	8674117	GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF.

P53038	TEL2_YEAST	Telomere length regulation protein TEL2	8649421	TEL2, an essential gene required for telomere length regulation and telomere position effect in Saccharomyces cerevisiae.

O43353	RIPK2_HUMAN	Receptor-interacting serine/threonine-protein kinase 2	9705938	Identification of CARDIAK, a RIP-like kinase that associates with caspase-1.

O35386	PAHX_MOUSE	Phytanoyl-CoA dioxygenase, peroxisomal	9326939	Identification of PAHX, a Refsum disease gene.

P31150	GDIA_HUMAN	Rab GDP dissociation inhibitor alpha	11809807	The hematopoiesis-specific GTP-binding protein RhoH is GTPase deficient and modulates activities of other Rho GTPases by an inhibitory function.

Q8INB9	AKT1_DROME	RAC serine/threonine-protein kinase	12172554	Akt regulates growth by directly phosphorylating Tsc2.

Q00597	FANCC_HUMAN	Fanconi anemia group C protein	1574115	Cloning of cDNAs for Fanconi's anaemia by functional complementation.

P51647	AL1A1_RAT	Retinal dehydrogenase 1	8543180	Cloning of a cDNA encoding rat aldehyde dehydrogenase with high activity for retinal oxidation.

Q8GXL3	SPL8_ARATH	Squamosa promoter-binding-like protein 8	12671094	SPL8, an SBP-box gene that affects pollen sac development in Arabidopsis.

Q9VFK6	SETD8_DROME	Histone-lysine N-methyltransferase pr-set7	15681608	PR-Set7-dependent methylation of histone H4 Lys 20 functions in repression of gene expression and is essential for mitosis.

P10499	KCNA1_RAT	Potassium voltage-gated channel subfamily A member 1	7477295	Clustering of Shaker-type K+ channels by interaction with a family of membrane-associated guanylate kinases.

Q15465	SHH_HUMAN	Sonic hedgehog protein	8896572	Mutations in the human Sonic hedgehog gene cause holoprosencephaly.

Q9VTN0	GR68A_DROME	Gustatory receptor 68a	12971900	A putative Drosophila pheromone receptor expressed in male-specific taste neurons is required for efficient courtship.

Q6AZ28	PIAS2_RAT	E3 SUMO-protein ligase PIAS2	11117529	ARIP3 (androgen receptor-interacting protein 3) and other PIAS (protein inhibitor of activated STAT) proteins differ in their ability to modulate steroid receptor-dependent transcriptional activation.

Q99665	I12R2_HUMAN	Interleukin-12 receptor subunit beta-2	8943050	A functional interleukin 12 receptor complex is composed of two beta- type cytokine receptor subunits.

O04719	P2C77_ARATH	Protein phosphatase 2C 77	19407142	Abscisic acid inhibits type 2C protein phosphatases via the PYR/PYL family of START proteins.

P91679	PEPT1_DROME	Peptide transporter family 1	9730971	The opt1 gene of Drosophila melanogaster encodes a proton-dependent dipeptide transporter.

P60903	S10AA_HUMAN	Protein S100-A10	1831433	Primary structure of human, chicken, and Xenopus laevis p11, a cellular ligand of the Src-kinase substrate, annexin II.

P41004	SMC4_SCHPO	Structural maintenance of chromosomes protein 4	10485849	Fission yeast condensin complex: essential roles of non-SMC subunits for condensation and Cdc2 phosphorylation of Cut3/SMC4.

P17787	ACHB2_HUMAN	Neuronal acetylcholine receptor subunit beta-2	8906617	Comparative structure of human neuronal alpha 2-alpha 7 and beta 2- beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits.

Q9R269	PEPL_MOUSE	Periplakin	12244133	Binding of protein kinase B to the plakin family member periplakin.

Q8R4F1	NTNG2_MOUSE	Netrin-G2	11804778	Complementary expression and neurite outgrowth activity of netrin-G subfamily members.

P34078	LTV1_YEAST	Protein LTV1	14562095	Global analysis of protein localization in budding yeast.

Q96S53	TESK2_HUMAN	Dual specificity testis-specific protein kinase 2	10512679	Identification and characterization of TESK2, a novel member of the LIMK/TESK family of protein kinases, predominantly expressed in testis.

O42872	RRP41_SCHPO	Exosome complex component ski6	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q09142	ORC2_SCHPO	Origin recognition complex subunit 2	8552194	Interaction of Cdc2 and Cdc18 with a fission yeast ORC2-like protein.

P20933	ASPG_HUMAN	N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	1904874	Characterization of the mutation responsible for aspartylglucosaminuria in three Finnish patients. Amino acid substitution Cys163-->Ser abolishes the activity of lysosomal glycosylasparaginase and its conversion into subunits.

P01830	THY1_RAT	Thy-1 membrane glycoprotein	2857477	Structural organization of the rat thy-1 gene.

P93009	CUTA_ARATH	Protein CutA, chloroplastic	12795705	The Arabidopsis thaliana CUTA gene encodes an evolutionarily conserved copper binding chloroplast protein.

P63040	CPLX1_MOUSE	Complexin-1	15126625	Complexin I regulates glucose-induced secretion in pancreatic beta- cells.

P47083	MPP10_YEAST	U3 small nucleolar RNA-associated protein MPP10	9315638	Mpp10p, a U3 small nucleolar ribonucleoprotein component required for pre-18S rRNA processing in yeast.

O15379	HDAC3_HUMAN	Histone deacetylase 3	10898795	BCoR, a novel corepressor involved in BCL-6 repression.

P04906	GSTP1_RAT	Glutathione S-transferase P	3029128	The structure of the rat glutathione S-transferase P gene and related pseudogenes.

O13688	NSE6_SCHPO	Non-structural maintenance of chromosome element 6	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q99PE2	ANRA2_MOUSE	Ankyrin repeat family A protein 2	11095640	Characterization of ANKRA, a novel ankyrin repeat protein that interacts with the cytoplasmic domain of megalin.

P97678	KCMB1_RAT	Calcium-activated potassium channel subunit beta-1	9105668	Differential expression of the alpha and beta subunits of the large- conductance calcium-activated potassium channel: implication for channel diversity.

P0A898	YBEY_ECOLI	Putative metalloprotease ybeY	16511207	The ybeY protein from Escherichia coli is a metalloprotein.

O74331	RLP1_SCHPO	DNA repair protein rlp1	14668362	Five RecA-like proteins of Schizosaccharomyces pombe are involved in meiotic recombination.

Q874I4	PYRD_CANAL	Dihydroorotate dehydrogenase, mitochondrial	16774642	Biochemical characterization of recombinant dihydroorotate dehydrogenase from the opportunistic pathogenic yeast Candida albicans.

Q03833	GIS1_YEAST	Transcriptional activator/repressor GIS1	10523651	RPH1 and GIS1 are damage-responsive repressors of PHR1.

Q05919	VPS38_YEAST	Vacuolar protein sorting-associated protein 38	11157979	Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae.

Q9DED4	CIRBB_XENLA	Cold-inducible RNA-binding protein B	13679363	Xenopus cold-inducible RNA-binding protein 2 interacts with ElrA, the Xenopus homolog of HuR, and inhibits deadenylation of specific mRNAs.

Q9VRJ0	GEN_DROME	Flap endonuclease GEN	17614965	DmGEN shows a flap endonuclease activity, cleaving the blocked-flap structure and model replication fork.

O22920	CHX13_ARATH	Cation/H(+) symporter 13	18676662	AtCHX13 is a plasma membrane K+ transporter.

P35763	PERF_RAT	Perforin-1	2809217	Molecular cloning of rat cytolysin.

Q91903	ELAV2_XENLA	ELAV-like protein 2	16930598	Xenopus ElrB, but not ElrA, binds RNA as an oligomer: possible role of the linker.

P81637	LECA_DIOGU	Lectin alpha chain	10082964	Molecular characterization and crystallization of Diocleinae lectins.

P53007	TXTP_HUMAN	Tricarboxylate transport protein, mitochondrial	8666394	Localization of the human mitochondrial citrate transporter protein gene to chromosome 22q11 in the DiGeorge syndrome critical region.

Q9Y253	POLH_HUMAN	DNA polymerase eta	10385124	The XPV (Xeroderma pigmentosum variant) gene encodes human DNA polymerase eta.

P77425	ALLC_ECOLI	Allantoate amidohydrolase	10601204	Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.

P0A746	MSRB_ECOLI	Peptide methionine sulfoxide reductase msrB	16251365	Insights into the role of the metal binding site in methionine-R- sulfoxide reductases B.

P61169	DRD2_RAT	D(2) dopamine receptor	10391935	Association of the D2 dopamine receptor third cytoplasmic loop with spinophilin, a protein phosphatase-1-interacting protein.

Q9BUN8	DERL1_HUMAN	Derlin-1	19818707	The otubain YOD1 is a deubiquitinating enzyme that associates with p97 to facilitate protein dislocation from the ER.

P61247	RS3A_HUMAN	40S ribosomal protein S3a	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

Q9NSB8	HOME2_HUMAN	Homer protein homolog 2	9808458	Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins.

P84085	ARF5_HUMAN	ADP-ribosylation factor 5	17030804	Structural basis for Rab11-dependent membrane recruitment of a family of Rab11-interacting protein 3 (FIP3)/Arfophilin-1.

Q13319	CD5R2_HUMAN	Cyclin-dependent kinase 5 activator 2	7592934	An isoform of the neuronal cyclin-dependent kinase 5 (Cdk5) activator.

P38891	BCA1_YEAST	Branched-chain-amino-acid aminotransferase, mitochondrial	8798704	Mitochondrial and cytosolic branched-chain amino acid transaminases from yeast, homologs of the myc oncogene-regulated Eca39 protein.

O60832	DKC1_HUMAN	H/ACA ribonucleoprotein complex subunit 4	9590285	X-linked dyskeratosis congenita is caused by mutations in a highly conserved gene with putative nucleolar functions.

Q9Y227	ENTP4_HUMAN	Ectonucleoside triphosphate diphosphohydrolase 4	9556635	Golgi localization and functional expression of human uridine diphosphatase.

P35318	ADML_HUMAN	ADM	8074714	Genomic structure of human adrenomedullin gene.

P23606	TGM1_RAT	Protein-glutamine gamma-glutamyltransferase K	1979171	Primary structure of keratinocyte transglutaminase.

A0AVX7	TESC_CHICK	Tescalcin	19345287	Expression and evolutionary conservation of the tescalcin gene during development.

P48050	IRK4_HUMAN	Inward rectifier potassium channel 4	8016146	Primary structure and characterization of a small-conductance inwardly rectifying potassium channel from human hippocampus.

Q8BL65	ABLM2_MOUSE	Actin-binding LIM protein 2	17194709	Two novel members of the ABLIM protein family, ABLIM-2 and -3, associate with STARS and directly bind F-actin.

O89019	INVS_MOUSE	Inversin	9771707	Inversin, a novel gene in the vertebrate left-right axis pathway, is partially deleted in the inv mouse.

Q9Z2Z8	DHCR7_RAT	7-dehydrocholesterol reductase	10329655	Cholesterol biosynthesis from lanosterol. Molecular cloning, tissue distribution, expression, chromosomal localization, and regulation of rat 7-dehydrocholesterol reductase, a Smith-Lemli-Opitz syndrome- related protein.

O70280	WFDC1_RAT	WAP four-disulfide core domain protein 1	9468514	Molecular cloning and expression of ps20 growth inhibitor. A novel WAP-type 'four-disulfide core' domain protein expressed in smooth muscle.

P53695	EXO1_SCHPO	Exodeoxyribonuclease 1	7855597	A role for exonuclease I from S. pombe in mutation avoidance and mismatch correction.

Q12870	TCF15_HUMAN	Transcription factor 15	8041747	Cloning and characterization of a basic helix-loop-helix protein expressed in early mesoderm and the developing somites.

Q9NHC3	CED2_CAEEL	Cell death abnormality protein 2	10707082	CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans.

Q9DGP9	DDX25_XENLA	ATP-dependent RNA helicase DDX25	11784096	Three-dimensional ultrastructural analysis of RNA distribution within germinal granules of Xenopus.

P24864	CCNE1_HUMAN	G1/S-specific cyclin-E1	17525332	ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

O76337	CED6_CAEEL	Cell death protein 6	11729193	Interaction of CED-6/GULP, an adapter protein involved in engulfment of apoptotic cells with CED-1 and CD91/low density lipoprotein receptor-related protein (LRP).

Q9LU68	CIA2_ARATH	Protein CHLOROPLAST IMPORT APPARATUS 2	11549763	Leaf-specific upregulation of chloroplast translocon genes by a CCT motif-containing protein, CIA2.

Q9Y6Y0	NS1BP_HUMAN	Influenza virus NS1A-binding protein	9696811	NS1-Binding protein (NS1-BP): a novel human protein that interacts with the influenza A virus nonstructural NS1 protein is relocalized in the nuclei of infected cells.

Q93356	HM37_CAEEL	Homeobox protein ceh-37	12711598	Sequence-specific binding to telomeric DNA by CEH-37, a homeodomain protein in the nematode Caenorhabditis elegans.

Q9FDW1	MYB44_ARATH	Transcription factor MYB44	18162593	Overexpression of AtMYB44 enhances stomatal closure to confer abiotic stress tolerance in transgenic Arabidopsis.

Q9EPQ8	TCF20_MOUSE	Transcription factor 20	10995766	The nuclear factor SPBP contains different functional domains and stimulates the activity of various transcriptional activators.

Q86BJ3	PIPE_DROME	Heparan sulfate 2-O-sulfotransferase pipe	15252019	Mapping of a substrate binding site in the protein disulfide isomerase-related chaperone wind based on protein function and crystal structure.

Q6ZPQ6	PITM2_MOUSE	Membrane-associated phosphatidylinositol transfer protein 2	10460238	A neuronal-specific mammalian homolog of the Drosophila retinal degeneration B gene with expression restricted to the retina and dentate gyrus.

P51681	CCR5_HUMAN	C-C chemokine receptor type 5	8663314	Molecular cloning and functional characterization of a novel human CC chemokine receptor (CCR5) for RANTES, MIP-1beta, and MIP-1alpha.

O44740	MEI2_CAEEL	Meiotic spindle formation protein 2	10809666	MEI-1/MEI-2 katanin-like microtubule severing activity is required for Caenorhabditis elegans meiosis.

Q92968	PEX13_HUMAN	Peroxisomal membrane protein PEX13	9653144	Identification of a human PTS1 receptor docking protein directly required for peroxisomal protein import.

P11362	FGFR1_HUMAN	Basic fibroblast growth factor receptor 1	10830168	Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity.

Q9WTW5	S22A3_MOUSE	Solute carrier family 22 member 3	10966924	Structure, function, and regional distribution of the organic cation transporter OCT3 in the kidney.

P36406	TRI23_HUMAN	E3 ubiquitin-protein ligase TRIM23	9671726	Localization of ADP-ribosylation factor domain protein 1 (ARD1) in lysosomes and Golgi apparatus.

P49281	NRAM2_HUMAN	Natural resistance-associated macrophage protein 2	18776082	Regulation of the divalent metal ion transporter DMT1 and iron homeostasis by a ubiquitin-dependent mechanism involving Ndfips and WWP2.

Q9C0U9	YQD3_SCHPO	Uncharacterized transporter PB1C11.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q08334	I10R2_HUMAN	Interleukin-10 receptor subunit beta	9312047	Identification and functional characterization of a second chain of the interleukin-10 receptor complex.

P0ABF6	CDD_ECOLI	Cytidine deaminase	8289286	Cytidine deaminase. The 2.3 A crystal structure of an enzyme: transition-state analog complex.

P12883	MYH7_HUMAN	Myosin-7	8514894	Skeletal muscle expression and abnormal function of beta-myosin in hypertrophic cardiomyopathy.

Q9VVV9	NKD_DROME	Protein naked cuticle	16849595	An unconventional nuclear localization motif is crucial for function of the Drosophila Wnt/wingless antagonist Naked cuticle.

Q9VT65	CANB_DROME	Calpain-B	10446155	Characterization of two recombinant Drosophila calpains. CALPA and a novel homolog, CALPB.

P22415	USF1_HUMAN	Upstream stimulatory factor 1	2249772	The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer.

Q9SVM8	GRP2_ARATH	Glycine-rich RNA-binding protein 2, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P23116	EIF3A_MOUSE	Eukaryotic translation initiation factor 3 subunit A	19114715	MILI, a PIWI-interacting RNA-binding protein, is required for germ Line stem cell self-renewal and appears to positively regulate translation.

Q9NV31	IMP3_HUMAN	U3 small nucleolar ribonucleoprotein protein IMP3	12655004	The human Imp3 and Imp4 proteins form a ternary complex with hMpp10, which only interacts with the U3 snoRNA in 60-80S ribonucleoprotein complexes.

Q9NZC2	TREM2_HUMAN	Triggering receptor expressed on myeloid cells 2	10799849	Inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes.

P38128	SMP1_YEAST	Transcription factor SMP1	12482976	Targeting the MEF2-like transcription factor Smp1 by the stress- activated Hog1 mitogen-activated protein kinase.

P53622	COPA_YEAST	Coatomer subunit alpha	8001155	Coatomer is essential for retrieval of dilysine-tagged proteins to the endoplasmic reticulum.

P31660	PRPC_ECOLI	2-methylcitrate synthase	9325432	Propionate oxidation in Escherichia coli: evidence for operation of a methylcitrate cycle in bacteria.

P20231	TRYB2_HUMAN	Tryptase beta-2	9920877	Characterization of genes encoding known and novel human mast cell tryptases on chromosome 16p13.3.

P32362	DCUP_RAT	Uroporphyrinogen decarboxylase	3658690	Rat uroporphyrinogen decarboxylase cDNA: nucleotide sequence and comparison to human uroporphyrinogen decarboxylase.

O94445	SUV3_SCHPO	ATP-dependent RNA helicase suv3, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9H0A8	COMD4_HUMAN	COMM domain-containing protein 4	15799966	COMMD proteins, a novel family of structural and functional homologs of MURR1.

Q8IPH9	SLOB_DROME	Slowpoke-binding protein	10230800	A dynamically regulated 14-3-3, Slob, and Slowpoke potassium channel complex in Drosophila presynaptic nerve terminals.

P55062	BI1_RAT	Bax inhibitor 1	8012111	A novel, conserved gene of the rat that is developmentally regulated in the testis.

Q02253	MMSA_RAT	Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial	2768248	Purification and characterization of methylmalonate-semialdehyde dehydrogenase from rat liver. Identity to malonate-semialdehyde dehydrogenase.

P83140	AFP1S_MALPA	Antifungal protein 1 small subunit	11118343	Potent heterologous antifungal proteins from cheeseweed (Malva parviflora).

P29506	UNC4_CAEEL	Homeobox protein unc-4	9165118	The Groucho-like transcription factor UNC-37 functions with the neural specificity gene unc-4 to govern motor neuron identity in C. elegans.

P12004	PCNA_HUMAN	Proliferating cell nuclear antigen	20129063	CRL4(Cdt2) E3 ubiquitin ligase monoubiquitinates PCNA to promote translesion DNA synthesis.

Q9VC45	ASP_DROME	Protein abnormal spindle	10073938	Abnormal spindle protein, Asp, and the integrity of mitotic centrosomal microtubule organizing centers.

P55201	BRPF1_HUMAN	Peregrin	18794358	Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexes.

P15385	KCNA4_RAT	Potassium voltage-gated channel subfamily A member 4	7477295	Clustering of Shaker-type K+ channels by interaction with a family of membrane-associated guanylate kinases.

O55233	CER1_MOUSE	Cerberus	9431803	Cerberus-like is a secreted factor with neutralizing activity expressed in the anterior primitive endoderm of the mouse gastrula.

Q39054	CNX1_ARATH	Molybdopterin biosynthesis protein CNX1	9341109	Molybdenum cofactor biosynthesis. The plant protein Cnx1 binds molybdopterin with high affinity.

P40549	MNT3_YEAST	Alpha-1,3-mannosyltransferase MNT3	10521541	Mnt2p and Mnt3p of Saccharomyces cerevisiae are members of the Mnn1p family of alpha-1,3-mannosyltransferases responsible for adding the terminal mannose residues of O-linked oligosaccharides.

Q9UIA0	CYH4_HUMAN	Cytohesin-4	10652308	Similarities in function and gene structure of cytohesin-4 and cytohesin-1, guanine nucleotide-exchange proteins for ADP-ribosylation factors.

P35331	NRCAM_CHICK	Neuronal cell adhesion molecule	2045418	Structure of a new nervous system glycoprotein, Nr-CAM, and its relationship to subgroups of neural cell adhesion molecules.

Q01827	VMAT2_RAT	Synaptic vesicular amine transporter	1505023	A cDNA that suppresses MPP+ toxicity encodes a vesicular amine transporter.

Q9QZR5	HIPK2_MOUSE	Homeodomain-interacting protein kinase 2	11078605	Identification and cloning of a CD43-associated serine/threonine kinase.

P25591	VAC17_YEAST	vacuole-related protein 17	12594460	Regulated degradation of a class V myosin receptor directs movement of the yeast vacuole.

O60869	EDF1_HUMAN	Endothelial differentiation-related factor 1	12040021	Multiprotein bridging factor-1 (MBF-1) is a cofactor for nuclear receptors that regulate lipid metabolism.

P14314	GLU2B_HUMAN	Glucosidase 2 subunit beta	9043864	A 3-Mb region for the familial hemiplegic migraine locus on 19p13.1- p13.2: exclusion of PRKCSH as a candidate gene.

Q9UQL6	HDAC5_HUMAN	Histone deacetylase 5	10220385	Three proteins define a class of human histone deacetylases related to yeast Hda1p.

P34926	MAP1A_RAT	Microtubule-associated protein 1A	9786987	Localization of postsynaptic density-93 to dendritic microtubules and interaction with microtubule-associated protein 1A.

O13762	YF2C_SCHPO	Uncharacterized ATP-dependent helicase C17A2.12	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q02932	KA120_YEAST	Importin beta-like protein KAP120	16581791	Kap120 functions as a nuclear import receptor for ribosome assembly factor Rpf1 in yeast.

Q12522	IF6_YEAST	Eukaryotic translation initiation factor 6	10206977	Cloning of murine translation initiation factor 6 and functional analysis of the homologous sequence YPR016c in Saccharomyces cerevisiae.

Q09177	RPAC2_SCHPO	DNA-directed RNA polymerases I and III subunit RPAC2	10079952	Molecular cloning and characteristics of rpc19+ and rpc40+ Schizosaccharomyces pombe genes, coding for common subunits of nuclear RNA polymerase I and III.

Q39659	MFPA_CUCSA	Glyoxysomal fatty acid beta-oxidation multifunctional protein MFP-a	8051146	Domains of the tetrafunctional protein acting in glyoxysomal fatty acid beta oxidation. Demonstration of epimerase and isomerase activities on a peptide lacking hydratase activity.

Q39101	FRI1_ARATH	Ferritin-1, chloroplastic	11672431	Structure and differential expression of the four members of the Arabidopsis thaliana ferritin gene family.

P78317	RNF4_HUMAN	E3 ubiquitin ligase RNF4	12885770	The RING finger protein RNF4, a co-regulator of transcription, interacts with the TRPS1 transcription factor.

Q53EK2	NSE1_SCHPO	Non-structural maintenance of chromosomes element 1	16478984	The Nse5-Nse6 dimer mediates DNA repair roles of the Smc5-Smc6 complex.

Q9USN7	HST2_SCHPO	NAD-dependent deacetylase hst2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O95295	SNAPN_HUMAN	SNARE-associated protein Snapin	15102850	Identification of snapin and three novel proteins (BLOS1, BLOS2, and BLOS3/reduced pigmentation) as subunits of biogenesis of lysosome- related organelles complex-1 (BLOC-1).

Q7GB25	AB5C_ARATH	ABC transporter C family member 5	14684837	Binding of sulfonylurea by AtMRP5, an Arabidopsis multidrug resistance-related protein that functions in salt tolerance.

Q9HDY2	YK18_SCHPO	Meiotically up-regulated protein PB1A10.08	12161753	The transcriptional program of meiosis and sporulation in fission yeast.

Q24117	DYL1_DROME	Dynein light chain 1, cytoplasmic	8628263	Cytoplasmic dynein (ddlc1) mutations cause morphogenetic defects and apoptotic cell death in Drosophila melanogaster.

P84715	ANF39_ORNAN	C-type natriuretic peptide	9663691	The natriuretic peptide (ovCNP-39) from platypus (Ornithorhynchus anatinus) venom relaxes the isolated rat uterus and promotes oedema and mast cell histamine release.

O23390	BARS1_ARATH	Baruol synthase	17705488	An oxidosqualene cyclase makes numerous products by diverse mechanisms: a challenge to prevailing concepts of triterpene biosynthesis.

P01609	KV117_HUMAN	Ig kappa chain V-I region Scw	4435756	The primary structure of a human immunoglobulin L-chain of kappa-type (Bence-Jones protein Scw.), II: the chymotryptic peptides and the complete amino acid sequence.

P36144	RL1D1_YEAST	Ribosome biogenesis protein UTP30	12150911	90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors.

Q9FNV9	MY113_ARATH	Transcription factor MYB113	16463103	The MYB transcription factor superfamily of Arabidopsis: expression analysis and phylogenetic comparison with the rice MYB family.

Q63481	RAB7L_RAT	Ras-related protein Rab-7L1	9177482	Cloning of two splicing variants of the novel Ras-related GTPase Rab29 which is predominately expressed in kidney.

Q5AU62	NMRA_EMENI	Nitrogen metabolite repression protein nmrA	9537404	Characterization of the Aspergillus nidulans nmrA gene involved in nitrogen metabolite repression.

P42641	OBG_ECOLI	GTPase ObgE/CgtA	16980477	The Escherichia coli GTPase CgtAE is involved in late steps of large ribosome assembly.

Q9LPC6	ARK2_ARATH	Armadillo repeat-containing kinesin-like protein 2	17971038	Armadillo repeat-containing kinesins and a NIMA-related kinase are required for epidermal-cell morphogenesis in Arabidopsis.

O00102	UBC7_SCHPO	Ubiquitin-conjugating enzyme E2-18 kDa	12456009	The fission yeast ubiquitin-conjugating enzymes UbcP3, Ubc15, and Rhp6 affect transcriptional silencing of the mating-type region.

O95278	EPM2A_HUMAN	Laforin	18070875	Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG).

O95750	FGF19_HUMAN	Fibroblast growth factor 19	9931477	Structure and expression of a novel human FGF, FGF-19, expressed in the fetal brain.

P70060	LDB1_XENLA	LIM domain-binding protein 1	12874135	Selective degradation of excess Ldb1 by Rnf12/RLIM confers proper Ldb1 expression levels and Xlim-1/Ldb1 stoichiometry in Xenopus organizer functions.

Q15003	CND2_HUMAN	Condensin complex subunit 2	11694586	Cell cycle-dependent expression and nucleolar localization of hCAP- H.

Q9NYW8	RBAK_HUMAN	RB-associated KRAB zinc finger protein	10702291	Cloning and characterization of a novel Kruppel-associated box family transcriptional repressor that interacts with the retinoblastoma gene product, RB.

Q9WU40	MAN1_MOUSE	Inner nuclear membrane protein Man1	10671519	MAN1, an inner nuclear membrane protein that shares the LEM domain with lamina-associated polypeptide 2 and emerin.

Q9VRX6	INX4_DROME	Innexin inx4	11973283	A germline-specific gap junction protein required for survival of differentiating early germ cells.

P21802	FGFR2_HUMAN	Fibroblast growth factor receptor 2	12591959	Structural basis by which alternative splicing confers specificity in fibroblast growth factor receptors.

Q7XAK4	GID2_ORYSJ	F-box protein GID2	14756772	GID2, an F-box subunit of the SCF E3 complex, specifically interacts with phosphorylated SLR1 protein and regulates the gibberellin- dependent degradation of SLR1 in rice.

Q04226	TAF11_YEAST	Transcription initiation factor TFIID subunit 11	10788514	Identification of two novel TAF subunits of the yeast Saccharomyces cerevisiae TFIID complex.

P48559	YPT11_YEAST	GTP-binding protein YPT11	11943201	Identification of the novel proteins Yip4p and Yip5p as Rab GTPase interacting factors.

O59779	YCY1_SCHPO	Uncharacterized protein C1235.01	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P13747	HLAE_HUMAN	HLA class I histocompatibility antigen, alpha chain E	3260916	HLA-E. A novel HLA class I gene expressed in resting T lymphocytes.

Q9XZ58	CSN5_DROME	COP9 signalosome complex subunit 5	12737805	The COP9 signalosome promotes degradation of Cyclin E during early Drosophila oogenesis.

Q9D0S4	NEUL2_MOUSE	Neuralized-like protein 2	14960280	Ozz-E3, a muscle-specific ubiquitin ligase, regulates beta-catenin degradation during myogenesis.

Q12046	CWC2_YEAST	Pre-mRNA-splicing factor CWC2	12088152	Characterization of interactions among the Cef1p-Prp19p-associated splicing complex.

Q9VJ33	NEDD8_DROME	NEDD8	12231629	Distinct protein degradation mechanisms mediated by Cul1 and Cul3 controlling Ci stability in Drosophila eye development.

Q99418	CYH2_HUMAN	Cytohesin-2	14654833	Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor.

Q8IN44	TOTA_DROME	Protein Turandot A	16611243	The MAPKKK Mekk1 regulates the expression of Turandot stress genes in response to septic injury in Drosophila.

Q09274	UN105_CAEEL	Degenerin-like protein unc-105	3744028	Mutations with dominant effects on the behavior and morphology of the nematode Caenorhabditis elegans.

P09021	HXA5_MOUSE	Homeobox protein Hox-A5	2890554	Expression of a homeo domain protein in noncontact-inhibited cultured cells and postmitotic neurons.

Q99584	S10AD_HUMAN	Protein S100-A13	19284995	S100A13-C2A binary complex structure-a key component in the acidic fibroblast growth factor for the non-classical pathway.

Q9LQT8	GAI_ARATH	DELLA protein GAI	15161962	The Arabidopsis mutant sleepy1gar2-1 protein promotes plant growth by increasing the affinity of the SCFSLY1 E3 ubiquitin ligase for DELLA protein substrates.

P00491	PNPH_HUMAN	Purine nucleoside phosphorylase	3029074	A human purine nucleoside phosphorylase deficiency caused by a single base change.

O35973	PER1_MOUSE	Period circadian protein homolog 1	19414593	Casein kinase 1 delta regulates the pace of the mammalian circadian clock.

Q01603	PERO_DROME	Peroxidase	15979004	The enzymatic component of Drosophila melanogaster chorion is the Pxd peroxidase.

Q15475	SIX1_HUMAN	Homeobox protein SIX1	15141091	SIX1 mutations cause branchio-oto-renal syndrome by disruption of EYA1-SIX1-DNA complexes.

P15498	VAV_HUMAN	Proto-oncogene vav	2477241	vav, a novel human oncogene derived from a locus ubiquitously expressed in hematopoietic cells.

Q9SV55	NINJA_ARATH	AFP homolog 2	20360743	NINJA connects the co-repressor TOPLESS to jasmonate signalling.

O14088	YER5_SCHPO	Uncharacterized oxidoreductase C2F3.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O75794	CD123_HUMAN	Cell division cycle protein 123 homolog	8601400	An amino acid change in novel protein D123 is responsible for temperature-sensitive G1-phase arrest in a mutant of rat fibroblast line 3Y1.

Q8IE51	Y13P1_PLAF7	Uncharacterized protein MAL13P1.147	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

O35964	SH3G1_RAT	Endophilin-A2	9238017	The SH3p4/Sh3p8/SH3p13 protein family: binding partners for synaptojanin and dynamin via a Grb2-like Src homology 3 domain.

Q9Z2U4	ELF4_MOUSE	ETS-related transcription factor Elf-4	12387738	The ETS protein MEF plays a critical role in perforin gene expression and the development of natural killer and NK-T cells.

Q92988	DLX4_HUMAN	Homeobox protein DLX-4	8975708	Genomic analysis of a new mammalian distal-less gene: Dlx7.

P31979	NUOF_ECOLI	NADH-quinone oxidoreductase subunit F	7607227	Isolation and characterization of the proton-translocating NADH: ubiquinone oxidoreductase from Escherichia coli.

P22217	TRX1_YEAST	Thioredoxin-1	9657146	LMA1 binds to vacuoles at Sec18p (NSF), transfers upon ATP hydrolysis to a t-SNARE (Vam3p) complex, and is released during fusion.

Q94F00	IMPL1_ARATH	Phosphatase IMPL1, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q86VP1	TAXB1_HUMAN	Tax1-binding protein 1	10920205	T6BP, a TRAF6-interacting protein involved in IL-1 signaling.

Q9WUH5	TRI10_MOUSE	Tripartite motif-containing protein 10	10207104	HERF1, a novel hematopoiesis-specific RING finger protein, is required for terminal differentiation of erythroid cells.

P53112	PEX14_YEAST	Peroxisomal membrane protein PEX14	9094717	Pex14p, a peroxisomal membrane protein binding both receptors of the two PTS-dependent import pathways.

Q13367	AP3B2_HUMAN	AP-3 complex subunit beta-2	7671305	Beta-NAP, a cerebellar degeneration antigen, is a neuron-specific vesicle coat protein.

P53150	LIF1_YEAST	Ligase-interacting factor 1	11711435	NHEJ regulation by mating type is exercised through a novel protein, Lif2p, essential to the ligase IV pathway.

Q15118	PDK1_HUMAN	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial	17683942	Distinct structural mechanisms for inhibition of pyruvate dehydrogenase kinase isoforms by AZD7545, dichloroacetate, and radicicol.

Q8VYZ0	ORTH2_ARATH	E3 ubiquitin-protein ligase ORTHRUS 2	18643997	ORTH/VIM proteins that regulate DNA methylation are functional ubiquitin E3 ligases.

O74845	YCY9_SCHPO	Uncharacterized WD repeat-containing protein C1235.09	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9V3V7	SPC25_DROME	Kinetochore protein Spc25	17333235	Spatial organization of a ubiquitous eukaryotic kinetochore protein network in Drosophila chromosomes.

P11466	OCTC_RAT	Peroxisomal carnitine O-octanoyltransferase	7495866	Molecular cloning and sequence analysis of the rat liver carnitine octanoyltransferase cDNA, its natural gene and the gene promoter.

P11362	FGFR1_HUMAN	Basic fibroblast growth factor receptor 1	9139660	Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors.

Q80W54	FACE1_MOUSE	CAAX prenyl protease 1 homolog	11399759	Biochemical studies of Zmpste24-deficient mice.

Q9HCU8	DPOD4_HUMAN	DNA polymerase delta subunit 4	16510448	Functional roles of p12, the fourth subunit of human DNA polymerase delta.

Q06147	LCB5_YEAST	Sphingoid long chain base kinase 5	9677363	The LCB4 (YOR171c) and LCB5 (YLR260w) genes of Saccharomyces encode sphingoid long chain base kinases.

Q9VX32	RG190_DROME	Rho GTPase-activating protein 190	11672527	Regulating axon branch stability: the role of p190 RhoGAP in repressing a retraction signaling pathway.

Q6ZS10	CL17A_HUMAN	C-type lectin domain family 17, member A	19419970	Prolectin, a glycan-binding receptor on dividing B cells in germinal centers.

P93834	HXK2_ARATH	Hexokinase-2	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q96BI1	S22AI_HUMAN	Solute carrier family 22 member 18	9744804	Functional characterization of ORCTL2 -- an organic cation transporter expressed in the renal proximal tubules.

P48668	K2C6C_HUMAN	Keratin, type II cytoskeletal 6C	9054461	Phosphorylation of human keratin 8 in vivo at conserved head domain serine 23 and at epidermal growth factor-stimulated tail domain serine 431.

Q99M76	STAG3_RAT	Cohesin subunit SA-3	11599053	Evaluation of the Stag3 gene and the synaptonemal complex in a rat model (as/as) for male infertility.

P54278	PMS2_HUMAN	Mismatch repair endonuclease PMS2	11793469	Polymorphisms and HNPCC: PMS2-MLH1 protein interactions diminished by single nucleotide polymorphisms.

P23804	MDM2_MOUSE	E3 ubiquitin-protein ligase Mdm2	10906133	A novel cellular protein (MTBP) binds to MDM2 and induces a G1 arrest that is suppressed by MDM2.

Q6AWX6	SCAR1_ARATH	Protein SCAR1	15534215	Activation of Arp2/3 complex-dependent actin polymerization by plant proteins distantly related to Scar/WAVE.

P01777	HV316_HUMAN	Ig heavy chain V-III region TEI	4522793	Variable region sequences of five human immunoglobulin heavy chains of the VH3 subgroup: definitive identification of four heavy chain hypervariable regions.

P48542	IRK6_MOUSE	G protein-activated inward rectifier potassium channel 2	7926018	Cloning provides evidence for a family of inward rectifier and G- protein coupled K+ channels in the brain.

Q9WVG6	CARM1_MOUSE	Histone-arginine methyltransferase CARM1	10381882	Regulation of transcription by a protein methyltransferase.

Q53H76	PLA1A_HUMAN	Phospholipase A1 member A	10196188	An alternative splicing form of phosphatidylserine-specific phospholipase A1 that exhibits lysophosphatidylserine-specific lysophospholipase activity in humans.

O42825	RHO1_CANAL	GTP-binding protein RHO1	9401032	Cloning of the RHO1 gene from Candida albicans and its regulation of beta-1,3-glucan synthesis.

Q29983	MICA_HUMAN	MHC class I polypeptide-related sequence A	11485740	MICA engagement by human Vgamma2Vdelta2 T cells enhances their antigen-dependent effector function.

Q9LJR3	SPA3_ARATH	Protein SPA1-RELATED 3	16854975	Arabidopsis SPA proteins regulate photoperiodic flowering and interact with the floral inducer CONSTANS to regulate its stability.

P63322	RALA_RAT	Ras-related protein Ral-A	7687439	Isolation of cDNA clones and tissue expression of rat ral A and ral B GTP-binding proteins.

Q13501	SQSTM_HUMAN	Sequestosome-1	8650207	Molecular cloning of a phosphotyrosine-independent ligand of the p56lck SH2 wdomain.

Q5RHD1	KDM7A_DANRE	Lysine-specific demethylase 7A	20194436	KDM7 is a dual demethylase for histone H3 Lys 9 and Lys 27 and functions in brain development.

Q96NT5	PCFT_HUMAN	Proton-coupled folate transporter	17129779	Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption.

P53141	MLC1_YEAST	Myosin light chain 1	15210731	Identification and functional analysis of the essential and regulatory light chains of the only type II myosin Myo1p in Saccharomyces cerevisiae.

Q9STP8	ACBP2_ARATH	Acyl-CoA-binding domain-containing protein 2	18182029	Overexpression of membrane-associated acyl-CoA-binding protein ACBP1 enhances lead tolerance in Arabidopsis.

Q8W4J9	RPP8_ARATH	Disease resistance protein RPP8	9811794	Intragenic recombination and diversifying selection contribute to the evolution of downy mildew resistance at the RPP8 locus of Arabidopsis.

Q08218	YO047_YEAST	Uncharacterized protein YOL047C	14562095	Global analysis of protein localization in budding yeast.

O80345	CDKF1_ARATH	Cyclin-dependent kinase F-1	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

Q9Y2Y9	KLF13_HUMAN	Krueppel-like factor 13	10023774	RFLAT-1: a new zinc finger transcription factor that activates RANTES gene expression in T lymphocytes.

P0A6U3	MNMG_ECOLI	tRNA uridine 5-carboxymethylaminomethyl modification enzyme mnmG	17062623	Further insights into the tRNA modification process controlled by proteins MnmE and GidA of Escherichia coli.

Q9Z2I4	ROBO3_MOUSE	Roundabout homolog 3	15084255	The divergent Robo family protein rig-1/Robo3 is a negative regulator of slit responsiveness required for midline crossing by commissural axons.

Q8NFG4	FLCN_HUMAN	Folliculin	18403135	Identification and characterization of a novel folliculin-interacting protein FNIP2.

Q63092	CAMKV_RAT	CaM kinase-like vesicle-associated protein	8283228	1G5: a calmodulin-binding, vesicle-associated, protein kinase-like protein enriched in forebrain neurites.

P13231	HATA_DICDI	Hisactophilin-1	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q99811	PRRX2_HUMAN	Paired mesoderm homeobox protein 2	11063257	Human PRRX1 and PRRX2 genes: cloning, expression, genomic localization, and exclusion as disease genes for Nager syndrome.

O35394	PRAF1_RAT	Prenylated Rab acceptor protein 1	10707984	Piccolo, a presynaptic zinc finger protein structurally related to bassoon.

Q9CQE1	NPS3A_MOUSE	Protein NipSnap homolog 3A	14651853	Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.

Q09892	HOG1_SCHPO	Mitogen-activated protein kinase sty1	9585505	Regulation of the fission yeast transcription factor Pap1 by oxidative stress: requirement for the nuclear export factor Crm1 (Exportin) and the stress-activated MAP kinase Sty1/Spc1.

Q6DE08	AUKBA_XENLA	Serine/threonine-protein kinase 12-A	12464631	Cohesin release is required for sister chromatid resolution, but not for condensin-mediated compaction, at the onset of mitosis.

Q94AG2	SERK1_ARATH	Somatic embryogenesis receptor kinase 1	16284306	Arabidopsis SOMATIC EMBRYOGENESIS RECEPTOR KINASES1 and 2 are essential for tapetum development and microspore maturation.

Q9SMN1	UMP8_ARATH	Uncharacterized protein At3g48680, mitochondrial	11743114	Proteomic approach to identify novel mitochondrial proteins in Arabidopsis.

P41948	MEP2_YEAST	Ammonium transporter MEP2	11069679	In vivo N-glycosylation of the mep2 high-affinity ammonium transporter of Saccharomyces cerevisiae reveals an extracytosolic N- terminus.

O54924	EXOC8_RAT	Exocyst complex component 8	9405631	Subunit structure of the mammalian exocyst complex.

Q60739	BAG1_MOUSE	BAG family molecular chaperone regulator 1	7834747	Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity.

P19538	CI_DROME	Protein cubitus interruptus	2166702	Cloning and characterization of the segment polarity gene cubitus interruptus Dominant of Drosophila.

O14495	LPP3_HUMAN	Lipid phosphate phosphohydrolase 3	9705349	Human type 2 phosphatidic acid phosphohydrolases. Substrate specificity of the type 2a, 2b, and 2c enzymes and cell surface activity of the 2a isoform.

P51136	GSK3_DICDI	Glycogen synthase kinase-3	10571182	The novel tyrosine kinase ZAK1 activates GSK3 to direct cell fate specification.

P60891	PRPS1_HUMAN	Ribose-phosphate pyrophosphokinase 1	17701900	Mutations in PRPS1, which encodes the phosphoribosyl pyrophosphate synthetase enzyme critical for nucleotide biosynthesis, cause hereditary peripheral neuropathy with hearing loss and optic neuropathy (cmtx5).

P38315	YBP1_YEAST	YAP1-binding protein 1	12743123	Ybp1 is required for the hydrogen peroxide-induced oxidation of the Yap1 transcription factor.

Q07897	CMS1_YEAST	Protein CMS1	14562095	Global analysis of protein localization in budding yeast.

O60934	NBN_HUMAN	Nibrin	9590180	Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome.

P30043	BLVRB_HUMAN	Flavin reductase	8117274	Cloning and nucleotide sequence of a cDNA of the human erythrocyte NADPH-flavin reductase.

P48549	IRK3_HUMAN	G protein-activated inward rectifier potassium channel 1	8804710	Cloning of a G protein-activated inwardly rectifying potassium channel from human cerebellum.

Q12411	MPC70_YEAST	Sporulation-specific protein 21	11973299	Ady3p links spindle pole body function to spore wall synthesis in Saccharomyces cerevisiae.

Q9JMH2	LRIT1_RAT	Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1	10777785	Molecular cloning of a novel membrane glycoprotein, Pal, specifically expressed in photoreceptor cells of the retina and containing leucine- rich repeat.

Q9LX66	HERK_ARATH	Receptor-like protein kinase HERK 1	19383785	Three related receptor-like kinases are required for optimal cell elongation in Arabidopsis thaliana.

P38328	ARPC1_YEAST	Actin-related protein 2/3 complex subunit 1	10377407	Genetic dissection of the budding yeast Arp2/3 complex: a comparison of the in vivo and structural roles of individual subunits.

Q9UQ13	SHOC2_HUMAN	Leucine-rich repeat protein SHOC-2	19684605	Mutation of SHOC2 promotes aberrant protein N-myristoylation and causes Noonan-like syndrome with loose anagen hair.

Q9Y4K3	TRAF6_HUMAN	TNF receptor-associated factor 6	10920205	T6BP, a TRAF6-interacting protein involved in IL-1 signaling.

Q944Q0	WNK8_ARATH	Serine/threonine-protein kinase WNK8	18761494	The plant WNK gene family and regulation of flowering time in Arabidopsis.

Q9Z2Y0	KEG1_RAT	Glycine N-acyltransferase-like protein Keg1	10470852	Structure of rat gamma-tubulin and its binding to HP33.

Q8K4Y5	LGI1_RAT	Leucine-rich glioma-inactivated protein 1	16504945	The epilepsy-linked Lgi1 protein assembles into presynaptic Kv1 channels and inhibits inactivation by Kvbeta1.

P48506	GSH1_HUMAN	Glutamate--cysteine ligase catalytic subunit	9675072	Expression and purification of human gamma-glutamylcysteine synthetase.

P22314	UBA1_HUMAN	Ubiquitin-like modifier-activating enzyme 1	16227972	Gigaxonin-controlled degradation of MAP1B light chain is critical to neuronal survival.

Q9NZA1	CLIC5_HUMAN	Chloride intracellular channel protein 5	12163479	AKAP350 at the Golgi apparatus. II. Association of AKAP350 with a novel chloride intracellular channel (CLIC) family member.

Q8ZQC8	SOPD2_SALTY	Secreted effector protein sopD2	12535274	SopD2 is a novel type III secreted effector of Salmonella typhimurium that targets late endocytic compartments upon delivery into host cells.

Q9CAY3	GPAT5_ARATH	Glycerol-3-phosphate acyltransferase 5	12897259	Arabidopsis AtGPAT1, a member of the membrane-bound glycerol-3- phosphate acyltransferase gene family, is essential for tapetum differentiation and male fertility.

Q9FXA3	BH095_ARATH	Transcription factor bHLH95	18567831	RETARDED GROWTH OF EMBRYO1, a new basic helix-loop-helix protein, expresses in endosperm to control embryo growth.

Q9LR44	IABG1_ARATH	Indole-3-acetate beta-glucosyltransferase 1	11283335	A novel UDP-glucose transferase is part of the callose synthase complex and interacts with phragmoplastin at the forming cell plate.

Q9BYX4	IFIH1_HUMAN	Interferon-induced helicase C domain-containing protein 1	19380577	Solution structures of cytosolic RNA sensor MDA5 and LGP2 C-terminal domains: identification of the RNA recognition loop in RIG-I-like receptors.

Q5PYH5	DLG1L_DANRE	Discs large homolog 1-like protein	15660367	Characterization of zebrafish PSD-95 gene family members.

P38774	DOG1_YEAST	2-deoxyglucose-6-phosphate phosphatase 1	8553694	DOGR1 and DOGR2: two genes from Saccharomyces cerevisiae that confer 2-deoxyglucose resistance when overexpressed.

P43631	KI2S2_HUMAN	Killer cell immunoglobulin-like receptor 2DS2	8627176	The human leukocyte antigen (HLA)-C-specific 'activatory' or 'inhibitory' natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions.

P87176	SLX8_SCHPO	E3 ubiquitin-protein ligase complex slx8-rfp subunit slx8	17762865	SUMO-targeted ubiquitin ligases in genome stability.

Q12525	MHT1_YEAST	Homocysteine S-methyltransferase 1	11013242	Reverse methionine biosynthesis from S-adenosylmethionine in eukaryotic cells.

P51842	GUC2F_RAT	Retinal guanylyl cyclase 2	7831337	Two membrane forms of guanylyl cyclase found in the eye.

P55869	AG2_XENLA	Anterior gradient protein 2	9533957	Anterior specification of embryonic ectoderm: the role of the Xenopus cement gland-specific gene XAG-2.

P46467	VPS4B_MOUSE	Vacuolar protein sorting-associated protein 4B	15173323	Mammalian class E Vps proteins, SBP1 and mVps2/CHMP2A, interact with and regulate the function of an AAA-ATPase SKD1/Vps4B.

P36334	SPIKE_CVHOC	Spike glycoprotein	11162792	Coronavirus spike proteins in viral entry and pathogenesis.

P08572	CO4A2_HUMAN	Collagen alpha-2(IV) chain	2846280	The genes for the alpha 1(IV) and alpha 2(IV) chains of human basement membrane collagen type IV are arranged head-to-head and separated by a bidirectional promoter of unique structure.

Q7Z614	SNX20_HUMAN	Sorting nexin-20	18196517	SLIC-1/sorting nexin 20: a novel sorting nexin that directs subcellular distribution of PSGL-1.

P55316	FOXG1_HUMAN	Forkhead box protein G1	7959731	Human brain factor 1, a new member of the fork head gene family.

Q7TNJ7	KCC1G_RAT	Calcium/calmodulin-dependent protein kinase type 1G	12753081	Cloning, characterization and expression of two alternatively splicing isoforms of Ca2+/calmodulin-dependent protein kinase I gamma in the rat brain.

Q9QZP2	PRDM4_RAT	PR domain zinc finger protein 4	10485890	Identification of a zinc finger protein whose subcellular distribution is regulated by serum and nerve growth factor.

Q8BGQ2	CSRN2_MOUSE	Cysteine/serine-rich nuclear protein 2	17726538	Characterization of a family of novel cysteine- serine-rich nuclear proteins (CSRNP).

Q5XF85	ATL42_ARATH	E3 ubiquitin-protein ligase ATL42	15644464	Functional analysis of the RING-type ubiquitin ligase family of Arabidopsis.

Q01105	SET_HUMAN	Protein SET	11909973	HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A.

Q86HN7	PLK_DICDI	Probable serine/threonine-protein kinase PLK	15548420	Molecular and functional analysis of the dictyostelium centrosome.

O43463	SUV91_HUMAN	Histone-lysine N-methyltransferase SUV39H1	10202156	Functional mammalian homologues of the Drosophila PEV-modifier Su(var)3-9 encode centromere-associated proteins which complex with the heterochromatin component M31.

O70591	PFD2_MOUSE	Prefoldin subunit 2	9630229	Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin.

Q99593	TBX5_HUMAN	T-box transcription factor TBX5	8988164	Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family.

P56273	MDM2_XENLA	E3 ubiquitin-protein ligase Mdm2	8875929	Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain.

Q9LH89	Y3885_ARATH	Uncharacterized protein At3g28850	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q9V521	PRPA3_DROME	Phenoloxidase subunit A3	12834045	Prophenol oxidase A3 in Drosophila melanogaster: activation and the PCR-based cDNA sequence.

Q8LEM7	CNBL3_ARATH	Calcineurin B-like protein 3	11230129	The NAF domain defines a novel protein-protein interaction module conserved in Ca(2+)-regulated kinases.

Q8VDF2	UHRF1_MOUSE	E3 ubiquitin-protein ligase UHRF1	9880673	Cloning and mapping of Np95 gene which encodes a novel nuclear protein associated with cell proliferation.

P84282	LECA_PHYAM	Lectin-A	7772833	Purification and characterization of three mitogenic lectins from the roots of pokeweed (Phytolacca americana).

Q8LGA1	CCD41_ARATH	Cyclin-D4-1	12857813	Arabidopsis D-type cyclin CYCD4;1 is a novel cyclin partner of B2- type cyclin-dependent kinase.

P30605	ITR1_YEAST	Myo-inositol transporter 1	2040626	Isolation and characterization of two distinct myo-inositol transporter genes of Saccharomyces cerevisiae.

P0C7Q2	ARMS2_HUMAN	Age-related maculopathy susceptibility protein 2	18511946	Age-related macular degeneration is associated with an unstable ARMS2 (LOC387715) mRNA.

Q9P7C8	SLD5_SCHPO	DNA replication complex GINS protein sld5	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8LGH4	CUL4_ARATH	Cullin-4	16792691	CUL4 associates with DDB1 and DET1 and its downregulation affects diverse aspects of development in Arabidopsis thaliana.

P52757	CHIO_HUMAN	Beta-chimaerin	7614486	Identification and characterization of human beta 2-chimaerin: association with malignant transformation in astrocytoma.

P42863	G6PIB_ORYSJ	Glucose-6-phosphate isomerase, cytosolic B	8722567	Characterization of cDNA encoding for phosphoglucose isomerase of rice (Oryza sativa L.).

Q10303	ALP21_SCHPO	Cell polarity protein alp21	10473641	Functional dissection and hierarchy of tubulin-folding cofactor homologues in fission yeast.

P34709	TRA2_CAEEL	Sex-determining transformer protein 2	10783162	Proteolysis in Caenorhabditis elegans sex determination: cleavage of TRA-2A by TRA-3.

P14291	RED1_YEAST	Protein RED1	2550770	Expression and DNA sequence of RED1, a gene required for meiosis I chromosome segregation in yeast.

Q12405	LPX1_YEAST	Peroxisomal membrane protein LPX1	12135984	Transcriptome profiling to identify genes involved in peroxisome assembly and function.

O04196	ISOA1_ARATH	Isoamylase 1, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q2PJ68	SGK1_CAEEL	Serine/threonine-protein kinase sgk-1	19240135	Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans.

O60656	UD19_HUMAN	UDP-glucuronosyltransferase 1-9	1910331	Cloning and stable expression of a new member of the human liver phenol/bilirubin: UDP-glucuronosyltransferase cDNA family.

Q99MR0	ACL6B_MOUSE	Actin-like protein 6B	17920018	Regulation of dendritic development by neuron-specific chromatin remodeling complexes.

O60462	NRP2_HUMAN	Neuropilin-2	9331348	Neuropilin-2, a novel member of the neuropilin family, is a high affinity receptor for the semaphorins Sema E and Sema IV but not Sema III.

Q8R4T9	UT2_MOUSE	Urea transporter 2	11029290	Molecular characterization of a novel UT-A urea transporter isoform (UT-A5) in testis.

P42699	PLAS2_ARATH	Plastocyanin major isoform, chloroplastic	8479917	Two cDNAs from the plant Arabidopsis thaliana that partially restore recombination proficiency and DNA-damage resistance to E. coli mutants lacking recombination-intermediate-resolution activities.

Q45VV3	YORKI_DROME	Protein yorkie	18313299	SCALLOPED interacts with YORKIE, the nuclear effector of the hippo tumor-suppressor pathway in Drosophila.

Q6IFY7	RTN1A_XENLA	Reticulon-1-A	17969151	Identification and expression of XRTN1-A and XRTN1-C in Xenopus laevis.

Q1ZXQ8	MTAA_DICDI	Centrosomal protein 224	15186508	The XMAP215-family protein DdCP224 is required for cortical interactions of microtubules.

O13822	YEE6_SCHPO	Uncharacterized oxidoreductase C19A8.06	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P81067	IRX3_MOUSE	Iroquois-class homeodomain protein IRX-3	10830170	A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube.

Q8QGV6	NLK2_XENLA	Serine/threonine-protein kinase NLK2	12047350	Involvement of NLK and Sox11 in neural induction in Xenopus development.

P31943	HNRH1_HUMAN	Heterogeneous nuclear ribonucleoprotein H	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

Q8R3P0	ACY2_MOUSE	Aspartoacylase	10837925	Murine aspartoacylase: cloning, expression and comparison with the human enzyme.

Q54YW1	ELMOA_DICDI	ELMO domain-containing protein A	18854143	An Elmo-like protein associated with myosin II restricts spurious F- actin events to coordinate phagocytosis and chemotaxis.

Q9HCN2	TPIP1_HUMAN	p53-regulated apoptosis-inducing protein 1	11030628	p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53.

Q9UQ84	EXO1_HUMAN	Exonuclease 1	10608837	The RAD2 domain of human exonuclease 1 exhibits 5' to 3' exonuclease and flap structure-specific endonuclease activities.

P50402	EMD_HUMAN	Emerin	7894480	Identification of a novel X-linked gene responsible for Emery- Dreifuss muscular dystrophy.

Q80T69	RSBN1_MOUSE	Round spermatid basic protein 1	14724137	Rosbin: a novel homeobox-like protein gene expressed exclusively in round spermatids.

P00918	CAH2_HUMAN	Carbonic anhydrase 2	1928091	Carbonic anhydrase II deficiency syndrome in a Belgian family is caused by a point mutation at an invariant histidine residue (107 His-->Tyr): complete structure of the normal human CA II gene.

Q12324	YVC1_YEAST	Calcium channel YVC1	11427713	A TRP homolog in Saccharomyces cerevisiae forms an intracellular Ca(2+)-permeable channel in the yeast vacuolar membrane.

O76074	PDE5A_HUMAN	cGMP-specific 3',5'-cyclic phosphodiesterase	9714779	Isolation and characterization of cDNAs encoding PDE5A, a human cGMP- binding, cGMP-specific 3',5'-cyclic nucleotide phosphodiesterase.

Q7Y1H8	IAA14_ORYSJ	Auxin-responsive protein IAA14	16200395	Structure and expression analysis of early auxin-responsive Aux/IAA gene family in rice (Oryza sativa).

O00233	PSMD9_HUMAN	26S proteasome non-ATPase regulatory subunit 9	9653651	cDNA cloning and characterization of a human proteasomal modulator subunit, p27 (PSMD9).

P21274	BMP2_MOUSE	Bone morphogenetic protein 2	14623234	Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot.

P04449	RL24A_YEAST	60S ribosomal protein L24-A	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q04964	SML1_YEAST	Ribonucleotide reductase inhibitor protein SML1	10593972	Yeast Sml1, a protein inhibitor of ribonucleotide reductase.

Q15414	RBY1A_HUMAN	RNA-binding motif protein, Y chromosome, family 1 member A1/C	8269511	A Y chromosome gene family with RNA-binding protein homology: candidates for the azoospermia factor AZF controlling human spermatogenesis.

P14681	KSS1_YEAST	Mitogen-activated protein kinase KSS1	9393860	MAP kinases with distinct inhibitory functions impart signaling specificity during yeast differentiation.

P13090	ATR1_YEAST	Aminotriazole resistance protein	2123132	Allelism of SNQ1 and ATR1, genes of the yeast Saccharomyces cerevisiae required for controlling sensitivity to 4-nitroquinoline-N- oxide and aminotriazole.

Q9Z0E8	S22A5_MOUSE	Solute carrier family 22 member 5	9916797	Primary systemic carnitine deficiency is caused by mutations in a gene encoding sodium ion-dependent carnitine transporter.

Q08237	REXO4_YEAST	RNA exonuclease 4	12364601	Deletions in the S1 domain of Rrp5p cause processing at a novel site in ITS1 of yeast pre-rRNA that depends on Rex4p.

Q9SIU2	NCBP1_ARATH	Nuclear cap-binding protein subunit 1	18550839	Dual roles of the nuclear cap-binding complex and SERRATE in pre-mRNA splicing and microRNA processing in Arabidopsis thaliana.

Q9ERI5	JMJD6_MOUSE	Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6	14715629	Defective fetal liver erythropoiesis and T lymphopoiesis in mice lacking the phosphatidylserine receptor.

Q8WVN6	SCTM1_HUMAN	Secreted and transmembrane protein 1	9480746	Identification and characterization of K12 (SECTM1), a novel human gene that encodes a Golgi-associated protein with transmembrane and secreted isoforms.

P35900	K1C20_HUMAN	Keratin, type I cytoskeletal 20	12857878	Keratin 20 helps maintain intermediate filament organization in intestinal epithelia.

Q63159	COQ3_RAT	Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial	8125303	Cloning of a rat cDNA encoding dihydroxypolyprenylbenzoate methyltransferase by functional complementation of a Saccharomyces cerevisiae mutant deficient in ubiquinone biosynthesis.

Q09781	RS3A1_SCHPO	40S ribosomal protein S1-A	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q924W6	TRI66_MOUSE	Tripartite motif-containing protein 66	15322135	TIF1delta, a novel HP1-interacting member of the transcriptional intermediary factor 1 (TIF1) family expressed by elongating spermatids.

Q8VWH2	HD3B_ORYSJ	Protein HEADING DATE 3B	19762423	A gene network for long-day flowering activates RFT1 encoding a mobile flowering signal in rice.

P40509	COPE_YEAST	Coatomer subunit epsilon	17101773	Involvement of specific COPI subunits in protein sorting from the late endosome to the vacuole in yeast.

Q94900	GLUCL_DROME	Glutamate-gated chloride channel	8702744	Identification of a Drosophila melanogaster glutamate-gated chloride channel sensitive to the antiparasitic agent avermectin.

P97290	IC1_MOUSE	Plasma protease C1 inhibitor	9652403	Molecular cloning, gene structure and expression profile of mouse C1 inhibitor.

P41990	APX1_CAEEL	Anterior pharynx in excess protein 1	8156602	The maternal genes apx-1 and glp-1 and establishment of dorsal- ventral polarity in the early C. elegans embryo.

Q9EQC7	FSTL3_MOUSE	Follistatin-related protein 3	11010968	Identification and characterization of a novel follistatin-like protein as a binding protein for the TGF-beta family.

P43497	CWP2_YEAST	Cell wall protein CWP2	7768807	Identification of three mannoproteins in the cell wall of Saccharomyces cerevisiae.

Q9Y5L2	HIG2_HUMAN	Hypoxia-inducible gene 2 protein	10690527	Epigenetic regulation of gene expression in cervical cancer cells by the tumor microenvironment.

O94632	MU158_SCHPO	Meiotically up-regulated gene 158 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P33750	DCA13_YEAST	Protein SOF1	12068309	A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis.

Q9FNX8	LOX4_ARATH	Lipoxygenase 4, chloroplastic	18949503	Diversity of the enzymatic activity in the lipoxygenase gene family of Arabidopsis thaliana.

Q9Y7U0	YCJE_SCHPO	Uncharacterized protein C63.14	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P10415	BCL2_HUMAN	Apoptosis regulator Bcl-2	9305631	BAG-1 modulates the chaperone activity of Hsp70/Hsc70.

Q6R327	RICTR_HUMAN	Rapamycin-insensitive companion of mTOR	15268862	Rictor, a novel binding partner of mTOR, defines a rapamycin- insensitive and raptor-independent pathway that regulates the cytoskeleton.

Q925J9	MED1_MOUSE	Mediator of RNA polymerase II transcription subunit 1	10882104	Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action.

P50391	NPY4R_HUMAN	Neuropeptide Y receptor type 4	8643460	Cloning and functional expression of cDNAs encoding human and rat pancreatic polypeptide receptors.

Q03400	SANT_PLAF7	S-antigen protein	1474992	A fourth family of the Plasmodium falciparum S-antigen.

Q9SJN0	ABI5_ARATH	Protein ABSCISIC ACID-INSENSITIVE 5	10760247	The Arabidopsis abscisic acid response gene ABI5 encodes a basic leucine zipper transcription factor.

P22985	XDH_RAT	Xanthine dehydrogenase/oxidase	15878860	Mechanism of the conversion of xanthine dehydrogenase to xanthine oxidase: identification of the two cysteine disulfide bonds and crystal structure of a non-convertible rat liver xanthine dehydrogenase mutant.

Q05029	BCH1_YEAST	Protein BCH1	14562095	Global analysis of protein localization in budding yeast.

Q03466	EBS1_YEAST	Protein EBS1	10688642	The Est1 subunit of yeast telomerase binds the Tlc1 telomerase RNA.

Q9NYV7	T2R16_HUMAN	Taste receptor type 2 member 16	10761934	A novel family of mammalian taste receptors.

Q9HCN6	GPVI_HUMAN	Platelet glycoprotein VI	11027634	Molecular cloning, genomic structure, chromosomal localization, and alternative splice forms of the platelet collagen receptor glycoprotein VI.

P09172	DOPO_HUMAN	Dopamine beta-hydroxylase	3443096	The primary structure of human dopamine-beta-hydroxylase: insights into the relationship between the soluble and the membrane-bound forms of the enzyme.

P53927	NOP15_YEAST	Ribosome biogenesis protein 15	14657029	Yeast Nop15p is an RNA-binding protein required for pre-rRNA processing and cytokinesis.

Q00973	B4GN1_HUMAN	Beta-1,4 N-acetylgalactosaminyltransferase 1	1601877	Expression cloning of beta 1,4 N-acetylgalactosaminyltransferase cDNAs that determine the expression of GM2 and GD2 gangliosides.

Q9VDW6	DMDA_DROME	Dystrophin, isoforms A/C/F/G/H	16399704	Dystrophin is required for appropriate retrograde control of neurotransmitter release at the Drosophila neuromuscular junction.

P83241	IP23_CAPAN	Proteinase inhibitor PSI-1.2	11604534	Proteins of circularly permuted sequence present within the same organism: the major serine proteinase inhibitor from Capsicum annuum seeds.

P38086	RDH54_YEAST	DNA repair and recombination protein RDH54	9409819	RDH54, a RAD54 homologue in Saccharomyces cerevisiae, is required for mitotic diploid-specific recombination and repair and for meiosis.

Q15291	RBBP5_HUMAN	Retinoblastoma-binding protein 5	19556245	On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex.

Q08119	ESC8_YEAST	Protein ESC8	12399377	Restoration of silencing in Saccharomyces cerevisiae by tethering of a novel Sir2-interacting protein, Esc8.

Q03899	YD131_YEAST	F-box protein YDR131C	10582239	SCF ubiquitin protein ligases and phosphorylation-dependent proteolysis.

Q8NER5	ACV1C_HUMAN	Activin receptor type-1C	12063393	cDNA cloning, expression studies and chromosome mapping of human type I serine/threonine kinase receptor ALK7 (ACVR1C).

Q6Y5D8	RHG10_MOUSE	Rho GTPase-activating protein 10	15471851	Identification and characterization of PS-GAP as a novel regulator of caspase-activated PAK-2.

O95630	STABP_HUMAN	STAM-binding protein	10383417	Possible involvement of a novel STAM-associated molecule 'AMSH' in intracellular signal transduction mediated by cytokines.

P13533	MYH6_HUMAN	Myosin-6	11815426	Sarcomere protein gene mutations in hypertrophic cardiomyopathy of the elderly.

Q8NFH3	NUP43_HUMAN	Nucleoporin Nup43	15146057	The entire Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis.

P35499	SCN4A_HUMAN	Sodium channel protein type 4 subunit alpha	1659948	Identification of a mutation in the gene causing hyperkalemic periodic paralysis.

O43508	TNF12_HUMAN	Tumor necrosis factor ligand superfamily member 12	14961121	Identification of an angiogenic factor that when mutated causes susceptibility to Klippel-Trenaunay syndrome.

Q9U8Q1	TGRD1_DICDI	Tiger protein D1	14651934	A cell-adhesion pathway regulates intercellular communication during Dictyostelium development.

Q769J6	ATS13_MOUSE	A disintegrin and metalloproteinase with thrombospondin motifs 13	15136581	Identification of strain-specific variants of mouse Adamts13 gene encoding von Willebrand factor-cleaving protease.

P19438	TNR1A_HUMAN	Tumor necrosis factor receptor superfamily member 1A	2158863	Molecular cloning and expression of a receptor for human tumor necrosis factor.

Q9R0C0	PLDN_MOUSE	Pallidin	12923531	Hermansky-Pudlak syndrome type 7 (HPS-7) results from mutant dysbindin, a member of the biogenesis of lysosome-related organelles complex 1 (BLOC-1).

P40499	ICE2_YEAST	Protein ICE2	14562095	Global analysis of protein localization in budding yeast.

Q22516	CHD3_CAEEL	Chromodomain-helicase-DNA-binding protein 3 homolog	11076750	The C. elegans Mi-2 chromatin-remodelling proteins function in vulval cell fate determination.

Q8L7G0	ARFA_ARATH	Auxin response factor 1	16176952	AUXIN RESPONSE FACTOR1 and AUXIN RESPONSE FACTOR2 regulate senescence and floral organ abscission in Arabidopsis thaliana.

P15646	FBRL_YEAST	rRNA 2'-O-methyltransferase fibrillarin	12068309	A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis.

P0A9H5	BTUR_ECOLI	Cob(I)yrinic acid a,c-diamide adenosyltransferase	2644187	Altered cobalamin metabolism in Escherichia coli btuR mutants affects btuB gene regulation.

P05421	DEM2_PHYSA	Dermorphin-2	7287299	Amino acid composition and sequence of dermorphin, a novel opiate- like peptide from the skin of Phyllomedusa sauvagei.

Q7M3S9	RNGB_DICDI	RING finger protein B	8647262	RNGB: a Dictyostelium RING finger protein that is specifically located in maturing spore cells.

P20936	RASA1_HUMAN	Ras GTPase-activating protein 1	9219684	The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants.

P38429	SAP30_YEAST	Transcriptional regulatory protein SAP30	16286008	Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex.

P35499	SCN4A_HUMAN	Sodium channel protein type 4 subunit alpha	1338909	Novel mutations in families with unusual and variable disorders of the skeletal muscle sodium channel.

Q9SYM1	Y1861_ARATH	Uncharacterized mscS family protein At1g78610	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q5FBC4	TMCC_DICDI	Tiny macrocysts protein C	15817229	Reverse genetic analyses of gamete-enriched genes revealed a novel regulator of the cAMP signaling pathway in Dictyostelium discoideum.

Q9SSF8	CDPKU_ARATH	Calcium-dependent protein kinase 30	8943201	Ca2+-dependent protein kinases and stress signal transduction in plants.

O74887	TSA1_SCHPO	Peroxiredoxin tpx1	15824112	Oxidation of a eukaryotic 2-Cys peroxiredoxin is a molecular switch controlling the transcriptional response to increasing levels of hydrogen peroxide.

P39958	GDI1_YEAST	Rab GDP-dissociation inhibitor	14576435	Structure of Rab GDP-dissociation inhibitor in complex with prenylated YPT1 GTPase.

Q09161	NCBP1_HUMAN	Nuclear cap-binding protein subunit 1	18423201	SKAR links pre-mRNA splicing to mTOR/S6K1-mediated enhanced translation efficiency of spliced mRNAs.

Q9JHC6	WISP2_RAT	WNT1-inducible-signaling pathway protein 2	9742130	Identification of rCop-1, a new member of the CCN protein family, as a negative regulator for cell transformation.

P08622	DNAJ_ECOLI	Chaperone protein dnaJ	12941935	The roles of the two zinc binding sites in DnaJ.

Q8L3Z8	FZR2_ARATH	Protein FIZZY-RELATED 2	19074624	FZR2/CCS52A1 expression is a determinant of endoreduplication and cell expansion in Arabidopsis.

Q9S814	EIN2_ARATH	Ethylene-insensitive protein 2	10381874	EIN2, a bifunctional transducer of ethylene and stress responses in Arabidopsis.

Q39254	CAX2_ARATH	Vacuolar cation/proton exchanger 2	15862304	Evidence of differential pH regulation of the Arabidopsis vacuolar Ca2+/H+ antiporters CAX1 and CAX2.

O14732	IMPA2_HUMAN	Inositol monophosphatase 2	17068342	Spatial expression patterns and biochemical properties distinguish a second myo-inositol monophosphatase IMPA2 from IMPA1.

O75976	CBPD_HUMAN	Carboxypeptidase D	9064476	Identification of a membrane-bound carboxypeptidase as the mammalian homolog of duck gp180, a hepatitis B virus-binding protein.

Q9P0G3	KLK14_HUMAN	Kallikrein-14	10969073	Tissue-specific expression patterns and fine mapping of the human kallikrein (KLK) locus on proximal 19q13.4.

Q9UJX2	CDC23_HUMAN	Cell division cycle protein 23 homolog	16364912	Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C.

Q96J02	ITCH_HUMAN	E3 ubiquitin-protein ligase Itchy homolog	20068034	The ubiquitin ligase itch regulates apoptosis by targeting thioredoxin-interacting protein for ubiquitin-dependent degradation.

Q08269	ALR1_YEAST	Magnesium transporter ALR1	9430719	Overexpression of the Saccharomyces cerevisiae magnesium transport system confers resistance to aluminum ion.

P40260	MEP1_YEAST	Ammonium transporter MEP1	11486013	Evidence that fungal MEP proteins mediate diffusion of the uncharged species NH(3) across the cytoplasmic membrane.

P83238	OSTCN_DANRE	Osteocalcin	14668966	Characterization of osteocalcin (BGP) and matrix Gla protein (MGP) fish specific antibodies: validation for immunodetection studies in lower vertebrates.

Q93PP9	BFR_DESDA	Bacterioferritin	11454214	The genetic organization of Desulfovibrio desulphuricans ATCC 27774 bacterioferritin and rubredoxin-2 genes: involvement of rubredoxin in iron metabolism.

P14585	LIN12_CAEEL	Protein lin-12	9389650	sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins.

Q99541	PLIN2_HUMAN	Perilipin-2	9003395	Adipocyte differentiation-related protein is secreted into milk as a constituent of milk lipid globule membrane.

Q92536	YLAT2_HUMAN	Y+L amino acid transporter 2	10903140	The heterodimeric amino acid transporter 4F2hc/y+LAT2 mediates arginine efflux in exchange with glutamine.

Q9HAY6	BCDO1_HUMAN	Beta,beta-carotene 15,15'-monooxygenase	11401432	Cloning and characterization of a human beta,beta-carotene-15,15- prime dioxygenase that is highly expressed in the retinal pigment epithelium.

P21926	CD9_HUMAN	CD9 antigen	11278880	The major CD9 and CD81 molecular partner. Identification and characterization of the complexes.

P38117	ETFB_HUMAN	Electron transfer flavoprotein subunit beta	8504797	cDNA cloning and mitochondrial import of the beta-subunit of the human electron-transfer flavoprotein.

Q08817	SOG2_YEAST	Leucine-rich repeat-containing protein SOG2	14562095	Global analysis of protein localization in budding yeast.

Q9HC10	OTOF_HUMAN	Otoferlin	10192385	A mutation in OTOF, encoding otoferlin, a FER-1-like protein, causes DFNB9, a nonsyndromic form of deafness.

Q9UJX2	CDC23_HUMAN	Cell division cycle protein 23 homolog	18485873	Mechanism of ubiquitin-chain formation by the human anaphase- promoting complex.

Q9Y693	LHFP_HUMAN	Lipoma HMGIC fusion partner	10329012	LHFP, a novel translocation partner gene of HMGIC in a lipoma, is a member of a new family of LHFP-like genes.

O74800	IMP1_SCHPO	Mitochondrial inner membrane protease subunit 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P77580	ACDH_ECOLI	Acetaldehyde dehydrogenase	16782065	Coupled expression of MhpE aldolase and MhpF dehydrogenase in Escherichia coli.

Q5FBC3	TMCB_DICDI	Tiny macrocysts protein B	15817229	Reverse genetic analyses of gamete-enriched genes revealed a novel regulator of the cAMP signaling pathway in Dictyostelium discoideum.

Q9UBR4	LHX3_HUMAN	LIM/homeobox protein Lhx3	10598593	Differential activation of pituitary hormone genes by human Lhx3 isoforms with distinct DNA binding properties.

O95373	IPO7_HUMAN	Importin-7	9214382	A novel class of RanGTP binding proteins.

P10040	CRB_DROME	Protein crumbs	11076972	Apical, lateral, and basal polarization cues contribute to the development of the follicular epithelium during Drosophila oogenesis.

Q12445	POM34_YEAST	Nucleoporin POM34	10684247	The yeast nuclear pore complex: composition, architecture, and transport mechanism.

Q9W1X8	FCL_DROME	Probable GDP-L-fucose synthase	16650000	Reconstitution in vitro of the GDP-fucose biosynthetic pathways of Caenorhabditis elegans and Drosophila melanogaster.

P42124	EZ_DROME	Histone-lysine N-methyltransferase E(z)	12408864	Histone methyltransferase activity of a Drosophila Polycomb group repressor complex.

Q08444	NOB1_YEAST	20S-pre-rRNA D-site endonuclease NOB1	12588997	Nob1p is required for cleavage of the 3' end of 18S rRNA.

Q13541	4EBP1_HUMAN	Eukaryotic translation initiation factor 4E-binding protein 1	16271312	Structural basis for mRNA cap-binding regulation of eukaryotic initiation factor 4E by 4E-binding protein, studied by spectroscopic, X-ray crystal structural, and molecular dynamics simulation methods.

Q9Y4E8	UBP15_HUMAN	Ubiquitin carboxyl-terminal hydrolase 15	10444327	Identification, functional characterization, and chromosomal localization of USP15, a novel human ubiquitin-specific protease related to the UNP oncoprotein, and a systematic nomenclature for human ubiquitin-specific proteases.

Q9SJN0	ABI5_ARATH	Protein ABSCISIC ACID-INSENSITIVE 5	18484180	A small plant-specific protein family of ABI five binding proteins (AFPs) regulates stress response in germinating Arabidopsis seeds and seedlings.

Q80XF5	I22R2_MOUSE	Interleukin-22 receptor subunit alpha-2	12700595	Cloning and characterization of mouse IL-22 binding protein.

A8E0R9	GRIP2_XENLA	Glutamate receptor-interacting protein 2	17320814	The mRNA coding for Xenopus glutamate receptor interacting protein 2 (XGRIP2) is maternally transcribed, transported through the late pathway and localized to the germ plasm.

Q80U28	MADD_MOUSE	MAP kinase-activating death domain protein	14735464	Antisense abrogation of DENN expression induces apoptosis of leukemia cells in vitro, causes tumor regression in vivo and alters the transcription of genes involved in apoptosis and the cell cycle.

Q6DJT9	PLAG1_HUMAN	Zinc finger protein PLAG1	9722527	Transcriptional activation capacity of the novel PLAG family of zinc finger proteins.

Q15080	NCF4_HUMAN	Neutrophil cytosol factor 4	8280052	p40phox, a third cytosolic component of the activation complex of the NADPH oxidase to contain src homology 3 domains.

O59801	YJV3_SCHPO	Uncharacterized helicase C550.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q6P1K2	PMF1_HUMAN	Polyamine-modulated factor 1	15502821	A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1.

O22932	CIPKB_ARATH	CBL-interacting serine/threonine-protein kinase 11	11230129	The NAF domain defines a novel protein-protein interaction module conserved in Ca(2+)-regulated kinases.

P40940	ARF3_ARATH	ADP-ribosylation factor 3	16236155	An Arabidopsis GRIP domain protein locates to the trans-Golgi and binds the small GTPase ARL1.

Q9QXK9	SH22A_MOUSE	SH2 domain-containing protein 2A	10587356	RIBP, a novel Rlk/Txk- and Itk-binding adaptor protein that regulates T cell activation.

P38435	VKGC_HUMAN	Vitamin K-dependent gamma-carboxylase	9845520	A missense mutation in gamma-glutamyl carboxylase gene causes combined deficiency of all vitamin K-dependent blood coagulation factors.

Q9DCV3	DGAT2_MOUSE	Diacylglycerol O-acyltransferase 2	11481335	Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members.

Q07532	IWR1_YEAST	Putative transcription factor IWR1	14562095	Global analysis of protein localization in budding yeast.

P0ACU5	FABR_ECOLI	HTH-type transcriptional repressor fabR	11160901	Phylogenetic footprinting of transcription factor binding sites in proteobacterial genomes.

O55245	TTHY_CROPO	Transthyretin	12228058	Crocodile transthyretin: structure, function, and evolution.

Q21065	IFA3_CAEEL	Intermediate filament protein ifa-3	14975728	Intermediate filaments are required for C. elegans epidermal elongation.

Q09882	PRP45_SCHPO	Pre-mRNA-processing protein 45	11884590	Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

O88588	PACS1_RAT	Phosphofurin acidic cluster sorting protein 1	9695949	PACS-1 defines a novel gene family of cytosolic sorting proteins required for trans-Golgi network localization.

Q920F6	SMC1B_MOUSE	Structural maintenance of chromosomes protein 1B	11564881	Novel meiosis-specific isoform of mammalian SMC1.

P19334	TRP_DROME	Transient receptor potential protein	10632594	Novel mechanism of massive photoreceptor degeneration caused by mutations in the trp gene of Drosophila.

Q8UUW7	KHDR1_CHICK	KH domain-containing, RNA-binding, signal transduction-associated protein 1	12163178	Retardation of the G2-M phase progression on gene disruption of RNA binding protein Sam68 in the DT40 cell line.

P24928	RPB1_HUMAN	DNA-directed RNA polymerase II subunit RPB1	9852112	Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.

Q9S7Z2	AFP4_ARATH	Ninja-family protein AFP4	18484180	A small plant-specific protein family of ABI five binding proteins (AFPs) regulates stress response in germinating Arabidopsis seeds and seedlings.

O23044	PER3_ARATH	Peroxidase 3	12366797	A novel cold-inducible gene from Arabidopsis, RCI3, encodes a peroxidase that constitutes a component for stress tolerance.

P62906	RL10A_HUMAN	60S ribosomal protein L10a	7609734	Identification of genes downregulated in the thymus by cyclosporin-A: preliminary characterization of clone CSA-19.

Q08214	NTG2_YEAST	DNA base excision repair N-glycosylase 2	10471279	Saccharomyces cerevisiae Ntg1p and Ntg2p: broad specificity N- glycosylases for the repair of oxidative DNA damage in the nucleus and mitochondria.

Q0IH87	PAX3B_XENLA	Paired box protein Pax-3-B	15843410	Neural crest determination by co-activation of Pax3 and Zic1 genes in Xenopus ectoderm.

O94677	COG6_SCHPO	Conserved oligomeric Golgi complex subunit 6	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P28300	LYOX_HUMAN	Protein-lysine 6-oxidase	1685472	Molecular cloning of human lysyl oxidase and assignment of the gene to chromosome 5q23.3-31.2.

P32131	HEMN_ECOLI	Oxygen-independent coproporphyrinogen-III oxidase	7768836	Cloning and characterization of the Escherichia coli hemN gene encoding the oxygen-independent coproporphyrinogen III oxidase.

Q9P793	MIT1_SCHPO	Chromatin remodeling factor mit1	17289569	SHREC, an effector complex for heterochromatic transcriptional silencing.

P83318	FAR3_PENMO	FMRFamide-like neuropeptide FLP3	11959015	Seven novel FMRFamide-like neuropeptide sequences from the eyestalk of the giant tiger prawn Penaeus monodon.

O00574	CXCR6_HUMAN	C-X-C chemokine receptor type 6	9166430	STRL33, A novel chemokine receptor-like protein, functions as a fusion cofactor for both macrophage-tropic and T cell line-tropic HIV- 1.

Q9R0R3	APEL_RAT	Apelin	10617103	Characterization of apelin, the ligand for the APJ receptor.

P16522	CDC23_YEAST	Anaphase-promoting complex subunit CDC23	12609981	Mnd2 and Swm1 are core subunits of the Saccharomyces cerevisiae anaphase-promoting complex.

P39723	SPC72_YEAST	Spindle pole component SPC72	9670012	Receptors determine the cellular localization of a gamma-tubulin complex and thereby the site of microtubule formation.

Q10198	NDC80_SCHPO	Kinetochore protein ndc80	16079914	Molecular analysis of kinetochore architecture in fission yeast.

Q06639	RSC3_YEAST	Chromatin structure-remodeling complex protein RSC3	10619019	Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains.

Q9Y615	ACL7A_HUMAN	Actin-like protein 7A	10373328	Cloning, mapping, and expression of two novel actin genes, actin- like-7A (ACTL7A) and actin-like-7B (ACTL7B), from the familial dysautonomia candidate region on 9q31.

P43235	CATK_HUMAN	Cathepsin K	7818555	Molecular cloning of human cDNA for cathepsin K: novel cysteine proteinase predominantly expressed in bone.

Q55FB8	PSLA_DICDI	Presporeless protein A	9636072	Identification and analysis of a gene that is essential for morphogenesis and prespore cell differentiation in Dictyostelium.

Q06682	UBX5_YEAST	UBX domain-containing protein 5	14562095	Global analysis of protein localization in budding yeast.

Q16254	E2F4_HUMAN	Transcription factor E2F4	14532282	HCF-1 functions as a coactivator for the zinc finger protein Krox20.

Q04969	SPC2_YEAST	Signal peptidase complex subunit SPC2	10921929	Interactions between Spc2p and other components of the endoplasmic reticulum translocation sites of the yeast Saccharomyces cerevisiae.

Q6NW58	SPAST_DANRE	Spastin	16893913	The microtubule-severing protein spastin is essential for axon outgrowth in the zebrafish embryo.

Q03790	NUP53_YEAST	Nucleoporin NUP53	11283351	A comprehensive two-hybrid analysis to explore the yeast protein interactome.

O34748	RECQ_BACSU	Probable ATP-dependent DNA helicase recQ	16385024	Recruitment of Bacillus subtilis RecN to DNA double-strand breaks in the absence of DNA end processing.

P02523	CRBB1_RAT	Beta-crystallin B1	11773034	Lens proteomics: analysis of rat crystallin sequences and two- dimensional electrophoresis map.

P77334	GMR_ECOLI	Cyclic di-GMP phosphodiesterase Gmr	17010156	Cyclic-di-GMP-mediated signalling within the sigma network of Escherichia coli.

Q9UBS5	GABR1_HUMAN	Gamma-aminobutyric acid type B receptor subunit 1	9753614	GABA (gamma-amino-butyric acid) neurotransmission: identification and fine mapping of the human GABAB receptor gene.

P28791	SEC20_YEAST	Protein transport protein SEC20	1537327	The Saccharomyces cerevisiae SEC20 gene encodes a membrane glycoprotein which is sorted by the HDEL retrieval system.

Q8N1N5	CRPAK_HUMAN	Cysteine-rich PAK1 inhibitor	16278681	CRIPak, a novel endogenous Pak1 inhibitor.

P53337	ERV29_YEAST	ER-derived vesicles protein ERV29	11157978	Erv41p and Erv46p: new components of COPII vesicles involved in transport between the ER and Golgi complex.

O13959	RBX1_SCHPO	RING-box protein pip1	16024659	A Rik1-associated, cullin-dependent E3 ubiquitin ligase is essential for heterochromatin formation.

Q6VMN6	PRLHR_MOUSE	Prolactin-releasing peptide receptor	14742914	The prolactin-releasing peptide receptor (GPR10) regulates body weight homeostasis in mice.

Q9UHD8	SEPT9_HUMAN	Septin-9	17922164	Characterization of a SEPT9 interacting protein, SEPT14, a novel testis-specific septin.

Q8C0Q2	ZHX3_MOUSE	Zinc fingers and homeoboxes protein 3	14659886	The mouse zinc-fingers and homeoboxes (ZHX) family: ZHX2 forms a heterodimer with ZHX3.

Q56YN3	NADK1_ARATH	NAD(H) kinase 1	15711971	Stress induces the expression of AtNADK-1, a gene encoding a NAD(H) kinase in Arabidopsis thaliana.

Q9ZP20	TRXM5_ORYSJ	Thioredoxin M5, chloroplastic	18723667	Abnormal chloroplast development and growth inhibition in rice thioredoxin m knock-down plants.

O43303	CE110_HUMAN	Centrosomal protein of 110 kDa	12361598	CP110, a cell cycle-dependent CDK substrate, regulates centrosome duplication in human cells.

Q02445	TFPI1_RAT	Tissue factor pathway inhibitor	1639767	cDNA cloning and expression of rat tissue factor pathway inhibitor (TFPI).

Q04359	SPO20_YEAST	Sporulation-specific protein 20	9425151	Prospore membrane formation defines a developmentally regulated branch of the secretory pathway in yeast.

P43567	AGX1_YEAST	Alanine--glyoxylate aminotransferase 1	14745783	Alanine:glyoxylate aminotransferase of Saccharomyces cerevisiae- encoding gene AGX1 and metabolic significance.

D0ZVG2	SSPH1_SALT1	E3 ubiquitin-protein ligase sspH1	16611232	A Salmonella type III secretion effector interacts with the mammalian serine/threonine protein kinase PKN1.

O75381	PEX14_HUMAN	Peroxisomal membrane protein PEX14	15146459	Identification of a new complementation group of the peroxisome biogenesis disorders and PEX14 as the mutated gene.

P78417	GSTO1_HUMAN	Glutathione S-transferase omega-1	10783391	Identification, characterization, and crystal structure of the Omega class glutathione transferases.

O60583	CCNT2_HUMAN	Cyclin-T2	9499409	Identification of multiple cyclin subunits of human P-TEFb.

O76014	KRT37_HUMAN	Keratin, type I cuticular Ha7	9756910	Characterization of a 190-kilobase pair domain of human type I hair keratin genes.

O89094	CASPE_MOUSE	Caspase-14	9823333	Identification and characterization of murine caspase-14, a new member of the caspase family.

Q16880	CGT_HUMAN	2-hydroxyacylsphingosine 1-beta-galactosyltransferase	8661025	The human gene CGT encoding the UDP-galactose ceramide galactosyl transferase (cerebroside synthase): cloning, characterization, and assignment to human chromosome 4, band q26.

P36148	GPT2_YEAST	Glycerol-3-phosphate O-acyltransferase 2	11544256	The initial step of the glycerolipid pathway: identification of glycerol-3-phosphate / dihydroxyacetone phosphate dual substrate acyltransferases in Saccharomyces cerevisiae.

P14404	EVI1_MOUSE	MDS1 and EVI1 complex locus protein EVI1	15889140	Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA-2 expression.

Q00839	HNRPU_HUMAN	Heterogeneous nuclear ribonucleoprotein U	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

Q9FKA7	ORTH1_ARATH	E3 ubiquitin-protein ligase ORTHRUS 1	17239600	The SRA methyl-cytosine-binding domain links DNA and histone methylation.

Q9QZS2	RNF4_MOUSE	E3 ubiquitin ligase RNF4	10822263	Rnf4, a RING protein expressed in the developing nervous and reproductive systems, interacts with Gscl, a gene within the DiGeorge critical region.

P61970	NTF2_HUMAN	Nuclear transport factor 2	7744965	Identification of NTF2, a cytosolic factor for nuclear import that interacts with nuclear pore complex protein p62.

O14976	GAK_HUMAN	Cyclin-G-associated kinase	9299234	Structure, expression, and chromosomal localization of human GAK.

P38883	RIX1_YEAST	Pre-rRNA-processing protein RIX1	14690591	Assigning function to yeast proteins by integration of technologies.

O09106	HDAC1_MOUSE	Histone deacetylase 1	12198165	The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription.

Q9VJS7	PBURS_DROME	Partner of bursicon	15811337	Drosophila molting neurohormone bursicon is a heterodimer and the natural agonist of the orphan receptor DLGR2.

Q9NNX6	CD209_HUMAN	CD209 antigen	11337487	Extensive repertoire of membrane-bound and soluble dendritic cell- specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts.

Q92585	MAML1_HUMAN	Mastermind-like protein 1	16530044	Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes.

Q15582	BGH3_HUMAN	Transforming growth factor-beta-induced protein ig-h3	9463327	Mutation hot spots in 5q31-linked corneal dystrophies.

Q9NZJ4	SACS_HUMAN	Sacsin	10655055	ARSACS, a spastic ataxia common in northeastern Quebec, is caused by mutations in a new gene encoding an 11.5-kb ORF.

P53207	SNU71_YEAST	U1 small nuclear ribonucleoprotein component SNU71	9630245	A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins.

Q7ZTU9	TBX2_DANRE	T-box transcription factor TBX2b	10331981	Zebrafish tbx-c functions during formation of midline structures.

Q9WVQ5	MTNB_MOUSE	Probable methylthioribulose-1-phosphate dehydratase	15262985	Induced inhibition of ischemic/hypoxic injury by APIP, a novel Apaf- 1-interacting protein.

P87377	VEGTA_XENLA	T-box protein VegT-A	9012537	The Xenopus T-box gene, Antipodean, encodes a vegetally localised maternal mRNA and can trigger mesoderm formation.

Q8K4Q8	COL12_MOUSE	Collectin-12	11564734	The membrane-type collectin CL-P1 is a scavenger receptor on vascular endothelial cells.

P0AB40	BHSA_ECOLI	Multiple stress resistance protein BhsA	17293424	YcfR (BhsA) influences Escherichia coli biofilm formation through stress response and surface hydrophobicity.

P14270	PDE4D_RAT	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	12834813	Cloning and characterization of novel PDE4D isoforms PDE4D6 and PDE4D7.

Q9EQ44	V1R41_MOUSE	Vomeronasal type-1 receptor 41	11116090	Sequence diversity and genomic organization of vomeronasal receptor genes in the mouse.

P36421	SYYC_YEAST	Tyrosyl-tRNA synthetase, cytoplasmic	8509419	Saccharomyces cerevisiae cytoplasmic tyrosyl-tRNA synthetase gene. Isolation by complementation of a mutant Escherichia coli suppressor tRNA defective in aminoacylation and sequence analysis.

P51168	SCNNB_HUMAN	Amiloride-sensitive sodium channel subunit beta	11244092	The Nedd4-like protein KIAA0439 is a potential regulator of the epithelial sodium channel.

Q9H8N7	ZN395_HUMAN	Zinc finger protein 395	14625278	Novel nuclear shuttle proteins, HDBP1 and HDBP2, bind to neuronal cell-specific cis-regulatory element in the promoter for the human Huntington's disease gene.

Q12464	RUVB2_YEAST	RuvB-like protein 2	12576485	Impairment of the DNA binding activity of the TATA-binding protein renders the transcriptional function of Rvb2p/Tih2p, the yeast RuvB- like protein, essential for cell growth.

Q9C101	YKT8_SCHPO	Uncharacterized MFS-type transporter PB1E7.08c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P36525	RM24_YEAST	54S ribosomal protein L24, mitochondrial	9151978	Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae.

P17609	YPT2_SCHPO	GTP-binding protein ypt2	2112089	Structural and functional analysis of ypt2, an essential ras-related gene in the fission yeast Schizosaccharomyces pombe encoding a Sec4 protein homologue.

P36955	PEDF_HUMAN	Pigment epithelium-derived factor	12737624	Pigment-epithelium-derived factor (PEDF) occurs at a physiologically relevant concentration in human blood: purification and characterization.

P61078	UB2D3_RAT	Ubiquitin-conjugating enzyme E2 D3	7826319	Molecular cloning, expression and characterization of a ubiquitin conjugation enzyme (E2(17)kB) highly expressed in rat testis.

O14645	IDLC_HUMAN	Axonemal dynein light intermediate polypeptide 1	9284741	Complementary deoxyribonucleic acid cloning and characterization of a putative human axonemal dynein light chain gene.

Q8QGV6	NLK2_XENLA	Serine/threonine-protein kinase NLK2	17785444	Nemo-like kinase-myocyte enhancer factor 2A signaling regulates anterior formation in Xenopus development.

P62628	DLRB1_RAT	Dynein light chain roadblock-type 1	10816553	Light-induced down-regulation of the rat class 1 dynein-associated protein robl/LC7-like gene in visual cortex.

P09874	PARP1_HUMAN	Poly [ADP-ribose] polymerase 1	9518481	Functional association of poly(ADP-ribose) polymerase with DNA polymerase alpha-primase complex: a link between DNA strand break detection and DNA replication.

P32320	CDD_HUMAN	Cytidine deaminase	9596658	Growth inhibition of granulocyte-macrophage colony forming cells by human cytidine deaminase requires the catalytic function of the protein.

Q920G9	GMCL1_MOUSE	Germ cell-less protein-like 1	12927808	Enhanced degradation of MDM2 by a nuclear envelope component, mouse germ cell-less.

Q14674	ESPL1_HUMAN	Separin	11509732	Cohesin cleavage by separase required for anaphase and cytokinesis in human cells.

P0A7X6	RIMM_ECOLI	Ribosome maturation factor rimM	9422595	RimM and RbfA are essential for efficient processing of 16S rRNA in Escherichia coli.

Q09170	CDS1_SCHPO	Serine/threonine-protein kinase cds1	7723827	A kinase from fission yeast responsible for blocking mitosis in S phase.

Q9ASS4	Y5838_ARATH	Probably inactive leucine-rich repeat receptor-like protein kinase At5g48380	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q15124	PGM5_HUMAN	Phosphoglucomutase-like protein 5	8631316	A novel dystrophin/utrophin-associated protein is an enzymatically inactive member of the phosphoglucomutase superfamily.

P52746	ZN142_HUMAN	Zinc finger protein 142	7557990	Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders.

Q9NQT5	EXOS3_HUMAN	Exosome complex exonuclease RRP40	11110791	Three novel components of the human exosome.

Q4W6B5	MPPB_DICDI	Mitochondrial-processing peptidase subunit beta	18603769	Antisense RNA inhibition of the beta subunit of the Dictyostelium discoideum mitochondrial processing peptidase induces the expression of mitochondrial proteins.

P40460	NDC80_YEAST	Kinetochore protein NDC80	11179222	The budding yeast proteins Spc24p and Spc25p interact with Ndc80p and Nuf2p at the kinetochore and are important for kinetochore clustering and checkpoint control.

P42522	MYOC_DICDI	Myosin IC heavy chain	8609164	Dictyostelium mutants lacking multiple classic myosin I isoforms reveal combinations of shared and distinct functions.

Q5Z749	IAA21_ORYSJ	Auxin-responsive protein IAA21	16200395	Structure and expression analysis of early auxin-responsive Aux/IAA gene family in rice (Oryza sativa).

P05067	A4_HUMAN	Amyloid beta A4 protein	10806211	Phosphorylation of the beta-amyloid precursor protein at the cell surface by ectocasein kinases 1 and 2.

P42643	14331_ARATH	14-3-3-like protein GF14 chi	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

Q9Y250	LZTS1_HUMAN	Leucine zipper putative tumor suppressor 1	10097140	The FEZ1 gene at chromosome 8p22 encodes a leucine-zipper protein, and its expression is altered in multiple human tumors.

Q08444	NOB1_YEAST	20S-pre-rRNA D-site endonuclease NOB1	12502737	Nob1p is required for biogenesis of the 26S proteasome and degraded upon its maturation in Saccharomyces cerevisiae.

O60830	TI17B_HUMAN	Mitochondrial import inner membrane translocase subunit Tim17-B	10339406	Genetic and structural characterization of the human mitochondrial inner membrane translocase.

Q9LR64	Y1360_ARATH	Thylakoid lumenal protein At1g03610, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q8JHW2	TSP3A_DANRE	Thrombospondin-3a	12592708	The zebrafish thrombospondin 3 and 4 genes (thbs3 and thbs4): cDNA and protein structure.

Q95ZG8	GBG_DICDI	Guanine nucleotide-binding protein subunit gamma	16135826	The phosducin-like protein PhLP1 is essential for Gbetagamma dimer formation in Dictyostelium discoideum.

P61169	DRD2_RAT	D(2) dopamine receptor	2974511	Cloning and expression of a rat D2 dopamine receptor cDNA.

P06241	FYN_HUMAN	Tyrosine-protein kinase Fyn	7822789	Human p59fyn(T) regulates OKT3-induced calcium influx by a mechanism distinct from PIP2 hydrolysis in Jurkat T cells.

O80340	ERF78_ARATH	Ethylene-responsive transcription factor 4	10715325	Arabidopsis ethylene responsive element binding factors act as transcriptional activators or repressors of GCC box mediated gene expression.

P07713	DECA_DROME	Protein decapentaplegic	15797386	Facilitated transport of a Dpp/Scw heterodimer by Sog/Tsg leads to robust patterning of the Drosophila blastoderm embryo.

Q9M0S5	ISOA3_ARATH	Isoamylase 3, chloroplastic	16495218	Evidence for distinct mechanisms of starch granule breakdown in plants.

P15877	DHG_ECOLI	Quinoprotein glucose dehydrogenase	8509415	Topological analysis of quinoprotein glucose dehydrogenase in Escherichia coli and its ubiquinone-binding site.

P54352	EAS_DROME	Ethanolamine kinase	7923374	The Drosophila easily shocked gene: a mutation in a phospholipid synthetic pathway causes seizure, neuronal failure, and paralysis.

Q9W517	WAPL_DROME	Protein wings apart-like	10747063	Genetic and molecular analysis of wings apart-like (wapl), a gene controlling heterochromatin organization in Drosophila melanogaster.

Q16775	GLO2_HUMAN	Hydroxyacylglutathione hydrolase, mitochondrial	15117945	The human hydroxyacylglutathione hydrolase (HAGH) gene encodes both cytosolic and mitochondrial forms of glyoxalase II.

Q9Y4A5	TRRAP_HUMAN	Transformation/transcription domain-associated protein	10966108	Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis.

Q04660	ERB1_YEAST	Ribosome biogenesis protein ERB1	16287855	Ytm1, Nop7, and Erb1 form a complex necessary for maturation of yeast 66S preribosomes.

Q92995	UBP13_HUMAN	Ubiquitin carboxyl-terminal hydrolase 13	9841226	The genomic organization of Isopeptidase T-3 (ISOT-3), a new member of the ubiquitin specific protease family (UBP).

P54277	PMS1_HUMAN	PMS1 protein homolog 1	8072530	Mutations of two PMS homologues in hereditary nonpolyposis colon cancer.

O17972	NPHP1_CAEEL	Nephrocystin-1-like protein	15659564	Expression and phenotype analysis of the nephrocystin-1 and nephrocystin-4 homologs in Caenorhabditis elegans.

P51957	NEK4_HUMAN	Serine/threonine-protein kinase Nek4	8208544	Two novel human serine/threonine kinases with homologies to the cell cycle regulating Xenopus MO15, and NIMA kinases: cloning and characterization of their expression pattern.

O35094	TIM44_RAT	Mitochondrial import inner membrane translocase subunit TIM44	9538267	Identification of the protein import components of the rat mitochondrial inner membrane, rTIM17, rTIM23, and rTIM44.

P29197	CH60A_ARATH	Chaperonin CPN60, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P61967	AP1S1_MOUSE	AP-1 complex subunit sigma-1A	2040623	AP17 and AP19, the mammalian small chains of the clathrin-associated protein complexes show homology to Yap17p, their putative homolog in yeast.

P40145	ADCY8_HUMAN	Adenylate cyclase type 8	8076676	Molecular cloning of the human type VIII adenylyl cyclase.

P38182	ATG8_YEAST	Autophagy-related protein 8	11149920	Membrane recruitment of Aut7p in the autophagy and cytoplasm to vacuole targeting pathways requires Aut1p, Aut2p, and the autophagy conjugation complex.

Q80UF7	TCAM1_MOUSE	TIR domain-containing adapter molecule 1	18849341	FLN29 deficiency reveals its negative regulatory role in the Toll- like receptor (TLR) and retinoic acid-inducible gene I (RIG-I)-like helicase signaling pathway.

Q15723	ELF2_HUMAN	ETS-related transcription factor Elf-2	8756667	Characterization of NERF, a novel transcription factor related to the Ets factor ELF-1.

Q05196	PABP5_ARATH	Polyadenylate-binding protein 5	8341686	Differential organ-specific expression of three poly(A)-binding- protein genes from Arabidopsis thaliana.

P22694	KAPCB_HUMAN	cAMP-dependent protein kinase catalytic subunit beta	2342480	Molecular cloning of a tissue-specific protein kinase (C gamma) from human testis -- representing a third isoform for the catalytic subunit of cAMP-dependent protein kinase.

P36212	RK123_ARATH	50S ribosomal protein L12-3, chloroplastic	8125949	Multicopy GTPase center protein L12 of Arabidopsis chloroplast ribosome is encoded by a clustered nuclear gene family with the expressed members closely linked to tRNA(Pro) genes.

Q556N5	ADRM1_DICDI	Proteasomal ubiquitin receptor ADRM1 homolog	16987957	A Phg2-Adrm1 pathway participates in the nutrient-controlled developmental response in Dictyostelium.

Q9H9Q4	NHEJ1_HUMAN	Non-homologous end-joining factor 1	16439204	Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly.

Q5AZC8	ABNB_EMENI	Arabinan endo-1,5-alpha-L-arabinosidase B	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

Q9LX20	ASPL1_ARATH	Aspartic proteinase-like protein 1	14517339	Proteomic analysis of glycosylphosphatidylinositol-anchored membrane proteins.

Q24297	RUXF_DROME	Small nuclear ribonucleoprotein F	1694092	Sequence and expression of two regulated transcription units during Drosophila melanogaster development: Deb-A and Deb-B.

P36630	CG22_SCHPO	G2/mitotic-specific cyclin cig2	11163211	The spike of S phase cyclin Cig2 expression at the G1-S border in fission yeast requires both APC and SCF ubiquitin ligases.

P81923	OR59A_DROME	Odorant receptor 59a	10069338	A novel family of divergent seven-transmembrane proteins: candidate odorant receptors in Drosophila.

O57682	PAX2B_XENLA	Paired box protein Pax-2-B	10491256	Synergism between Pax-8 and lim-1 in embryonic kidney development.

Q92185	SIA8A_HUMAN	Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase	8195250	Expression cloning of a GM3-specific alpha-2,8-sialyltransferase (GD3 synthase).

Q9P797	NU131_SCHPO	Nucleoporin nup131	15226438	The fission yeast Nup107-120 complex functionally interacts with the small GTPase Ran/Spi1 and is required for mRNA export, nuclear pore distribution, and proper cell division.

Q00987	MDM2_HUMAN	E3 ubiquitin-protein ligase Mdm2	10722742	Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53.

Q9EPK7	XPO7_MOUSE	Exportin-7	11071879	Identification of a novel putative Ran-binding protein and its close homologue.

P83306	JAP2_RANJA	Japonicin-2	11835990	Antimicrobial peptides with atypical structural features from the skin of the Japanese brown frog Rana japonica.

P04601	NEF_HV1H2	Nef protein	15569716	HIV-1 Nef disrupts MHC-I trafficking by recruiting AP-1 to the MHC-I cytoplasmic tail.

P01775	HV314_HUMAN	Ig heavy chain V-III region LAY	4139708	Structure of antibodies with shared idiotypy: the complete sequence of the heavy chain variable regions of two immunoglobulin M anti-gamma globulins.

Q7YQK3	4F2_RABIT	4F2 cell-surface antigen heavy chain	16125134	Site-directed mutagenesis of cysteine residues of large neutral amino acid transporter LAT1.

Q9NZB8	MOCS1_HUMAN	Molybdenum cofactor biosynthesis protein 1	9731530	Mutations in a polycistronic nuclear gene associated with molybdenum cofactor deficiency.

O15146	MUSK_HUMAN	Muscle, skeletal receptor tyrosine-protein kinase	7546737	Receptor tyrosine kinase specific for the skeletal muscle lineage: expression in embryonic muscle, at the neuromuscular junction, and after injury.

P87074	RHP9_SCHPO	DNA repair protein rhp9	9407031	Damage and replication checkpoint control in fission yeast is ensured by interactions of Crb2, a protein with BRCT motif, with Cut5 and Chk1.

Q8BR86	KIRR3_MOUSE	Kin of IRRE-like protein 3	12665856	A stromal cell-derived membrane protein that supports hematopoietic stem cells.

P69723	VIF_HV1H2	Virion infectivity factor	14564014	Induction of APOBEC3G ubiquitination and degradation by an HIV-1 Vif- Cul5-SCF complex.

Q9Y238	DLEC1_HUMAN	Deleted in lung and esophageal cancer protein 1	10213508	Molecular cloning of a candidate tumor suppressor gene, DLC1, from chromosome 3p21.3.

Q9JKL5	TESC_MOUSE	Tescalcin	19345287	Expression and evolutionary conservation of the tescalcin gene during development.

P53104	ATG1_YEAST	Serine/threonine-protein kinase ATG1	11689437	The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation.

P11161	EGR2_HUMAN	Early growth response protein 2	14532282	HCF-1 functions as a coactivator for the zinc finger protein Krox20.

P55199	ELL_HUMAN	RNA polymerase II elongation factor ELL	8596958	An RNA polymerase II elongation factor encoded by the human ELL gene.

P11245	ARY2_HUMAN	Arylamine N-acetyltransferase 2	2340091	Human arylamine N-acetyltransferase genes: isolation, chromosomal localization, and functional expression.

P38804	SDO1L_YEAST	SDO1-like protein YHR087W	14562095	Global analysis of protein localization in budding yeast.

Q9PVZ4	INSR_XENLA	Insulin receptor	1847619	Insulin and insulin-like-growth-factor-I (IGF-I) receptors in Xenopus laevis oocytes. Comparison with insulin receptors from liver and muscle.

P37388	XYLG_ECOLI	Xylose import ATP-binding protein XylG	9673030	Utilization of D-ribose through D-xylose transporter.

Q11107	LIN13_CAEEL	Zinc finger protein lin-13	10880475	Caenorhabditis elegans lin-13, a member of the LIN-35 Rb class of genes involved in vulval development, encodes a protein with zinc fingers and an LXCXE motif.

Q06625	GDE_YEAST	Glycogen debranching enzyme	11094287	The Saccharomyces cerevisiae YPR184w gene encodes the glycogen debranching enzyme.

O74910	RAF1_SCHPO	Rik1-associated factor 1	16157682	The Clr7 and Clr8 directionality factors and the Pcu4 cullin mediate heterochromatin formation in the fission yeast Schizosaccharomyces pombe.

Q9GZT6	CC90B_HUMAN	Coiled-coil domain-containing protein 90B, mitochondrial	11256614	Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.

O88551	CLD1_MOUSE	Claudin-1	10508613	Ca(2+)-independent cell-adhesion activity of claudins, a family of integral membrane proteins localized at tight junctions.

C0LGR3	Y4265_ARATH	Probable LRR receptor-like serine/threonine-protein kinase At4g26540	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P10586	PTPRF_HUMAN	Receptor-type tyrosine-protein phosphatase F	10338209	Crystal structure of the tandem phosphatase domains of RPTP LAR.

Q12905	ILF2_HUMAN	Interleukin enhancer-binding factor 2	11790298	Directed proteomic analysis of the human nucleolus.

P35820	PSC_DROME	Polycomb group protein Psc	11583617	Reconstitution of a functional core polycomb repressive complex.

P16143	PO2F1_XENLA	POU domain, class 2, transcription factor 1	1406629	Histone H2B gene transcription during Xenopus early development requires functional cooperation between proteins bound to the CCAAT and octamer motifs.

P04620	REV_HV1BR	Protein Rev	9405152	Interactions between HIV Rev and nuclear import and export factors: the Rev nuclear localisation signal mediates specific binding to human importin-beta.

Q8N4T8	CBR4_HUMAN	Carbonyl reductase family member 4	19000905	Human carbonyl reductase 4 is a mitochondrial NADPH-dependent quinone reductase.

P40858	RN49_YEAST	54S ribosomal protein L49, mitochondrial	9151978	Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae.

Q92830	KAT2A_HUMAN	Histone acetyltransferase KAT2A	10373431	Identification of TATA-binding protein-free TAFII-containing complex subunits suggests a role in nucleosome acetylation and signal transduction.

Q9NZ08	ERAP1_HUMAN	Endoplasmic reticulum aminopeptidase 1	11056387	Characterization of recombinant human adipocyte-derived leucine aminopeptidase expressed in Chinese hamster ovary cells.

Q9Y605	MOFA1_HUMAN	MORF4 family-associated protein 1	11500496	MRG15 activates the B-myb promoter through formation of a nuclear complex with the retinoblastoma protein and the novel protein PAM14.

P47019	ALB1_YEAST	Ribosome biogenesis protein ALB1	14562095	Global analysis of protein localization in budding yeast.

O60264	SMCA5_HUMAN	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5	9730600	Cloning and mapping of SMARCA5 encoding hSNF2H, a novel human homologue of Drosophila ISWI.

P78972	SLP1_SCHPO	WD repeat-containing protein slp1	15791259	Fission yeast Mes1p ensures the onset of meiosis II by blocking degradation of cyclin Cdc13p.

Q8RWV3	CCL11_ARATH	Cyclin-L1-1	12047626	Expression of Arabidopsis SR-like splicing proteins confers salt tolerance to yeast and transgenic plants.

P00724	INV2_YEAST	Invertase 2	6341817	The secreted form of invertase in Saccharomyces cerevisiae is synthesized from mRNA encoding a signal sequence.

Q9FHD5	CRR57_ARATH	Cysteine-rich repeat secretory protein 57	12805588	Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis.

O95178	NDUB2_HUMAN	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial	9878551	cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed.

O75841	UPK1B_HUMAN	Uroplakin-1b	9935153	Cloning of the human uroplakin 1B cDNA and analysis of its expression in urothelial-tumor cell lines and bladder-carcinoma tissue.

P20273	CD22_HUMAN	B-cell receptor CD22	8647200	Involvement of p72syk kinase, p53/56lyn kinase and phosphatidyl inositol-3 kinase in signal transduction via the human B lymphocyte antigen CD22.

P53685	HST1_YEAST	NAD-dependent deacetylase HST1	11711434	The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program.

Q91550	ILF3A_XENLA	Interleukin enhancer-binding factor 3-A	7922339	Binding properties of newly identified Xenopus proteins containing dsRNA-binding motifs.

P32942	ICAM3_HUMAN	Intercellular adhesion molecule 3	1448173	Molecular cloning of ICAM-3, a third ligand for LFA-1, constitutively expressed on resting leukocytes.

P17890	RPC7_YEAST	DNA-directed RNA polymerase III subunit RPC7	2201900	The RPC31 gene of Saccharomyces cerevisiae encodes a subunit of RNA polymerase C (III) with an acidic tail.

Q9ULH7	MKL2_HUMAN	MKL/myocardin-like protein 2	14565952	Megakaryoblastic leukemia-1/2, a transcriptional co-activator of serum response factor, is required for skeletal myogenic differentiation.

Q6TMJ3	SIGJ_DICDI	SrfA-induced gene J protein	17517120	STATc is a key regulator of the transcriptional response to hyperosmotic shock.

Q8VHJ7	PRGC2_MOUSE	Peroxisome proliferator-activated receptor gamma coactivator 1-beta	18483224	Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex.

Q00059	TFAM_HUMAN	Transcription factor A, mitochondrial	12897151	Human mitochondrial transcription factor B1 interacts with the C- terminal activation region of h-mtTFA and stimulates transcription independently of its RNA methyltransferase activity.

P82094	TMF1_HUMAN	TATA element modulatory factor	1409643	Cloning and chromosomal mapping of a human immunodeficiency virus 1 'TATA' element modulatory factor.

P43637	TOS3_YEAST	Serine/threonine-protein kinase TOS3	16201971	Purification and characterization of the three Snf1-activating kinases of Saccharomyces cerevisiae.

P14693	SAM35_YEAST	Sorting assembly machinery 35 kDa subunit	15067005	Sam35 of the mitochondrial protein sorting and assembly machinery is a peripheral outer membrane protein essential for cell viability.

P54227	STMN1_MOUSE	Stathmin	7724523	Stathmin interaction with a putative kinase and coiled-coil-forming protein domains.

Q9SRE6	CML38_ARATH	Calcium-binding protein CML38	17579812	Developmental and stimulus-induced expression patterns of Arabidopsis calmodulin-like genes CML37, CML38 and CML39.

Q9XZ08	EXT3_DROME	Exostosin-3	14645127	Three Drosophila EXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans.

P0ACC7	GLMU_ECOLI	Bifunctional protein glmU	8555230	Acetyltransfer precedes uridylyltransfer in the formation of UDP-N- acetylglucosamine in separable active sites of the bifunctional GlmU protein of Escherichia coli.

P38882	UTP9_YEAST	U3 small nucleolar RNA-associated protein 9	12068309	A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis.

P0AF63	NSRR_ECOLI	HTH-type transcriptional repressor nsrR	16428390	The yjeB (nsrR) gene of Escherichia coli encodes a nitric oxide- sensitive transcriptional regulator.

Q62768	UN13A_RAT	Protein unc-13 homolog A	7559667	Mammalian homologues of Caenorhabditis elegans unc-13 gene define novel family of C2-domain proteins.

O80840	PMM_ARATH	Phosphomannomutase	17217471	Molecular and functional analysis of phosphomannomutase (PMM) from higher plants and genetic evidence for the involvement of PMM in ascorbic acid biosynthesis in Arabidopsis and Nicotiana benthamiana.

Q01973	ROR1_HUMAN	Tyrosine-protein kinase transmembrane receptor ROR1	1334494	A novel family of cell surface receptors with tyrosine kinase-like domain.

O75820	ZN189_HUMAN	Zinc finger protein 189	9653648	Cloning and characterization of ZNF189, a novel human Kruppel-like zinc finger gene localized to chromosome 9q22-q31.

Q14512	FGFP1_HUMAN	Fibroblast growth factor-binding protein 1	16257968	Identification of the fibroblast growth factor (FGF)-interacting domain in a secreted FGF-binding protein by phage display.

P83177	HCY2_CARMA	Hemocyanin subunit 2	2620501	The relationship between N-terminal sequences and immunological characterization of crustacean hemocyanins.

P36116	VPS51_YEAST	Vacuolar protein sorting-associated protein 51	11957109	Large-scale identification of genes important for apical growth in Saccharomyces cerevisiae by directed allele replacement technology (DART) screening.

Q9Y605	MOFA1_HUMAN	MORF4 family-associated protein 1	14506250	MRGX is a novel transcriptional regulator that exhibits activation or repression of the B-myb promoter in a cell type-dependent manner.

Q6UXE8	BTNL3_HUMAN	Butyrophilin-like protein 3	10429365	Cloning, expression analysis, and chromosomal localization of a novel butyrophilin-like receptor.

P46951	YPP1_YEAST	Cargo-transport protein YPP1	14562095	Global analysis of protein localization in budding yeast.

Q94490	UBCB_DICDI	Ubiquitin conjugating enzyme E2 B	9832508	A novel, putative MEK kinase controls developmental timing and spatial patterning in Dictyostelium and is regulated by ubiquitin- mediated protein degradation.

P62877	RBX1_HUMAN	E3 ubiquitin-protein ligase RBX1	19250909	E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification.

P31431	SDC4_HUMAN	Syndecan-4	1500433	Molecular cloning of amphiglycan, a novel integral membrane heparan sulfate proteoglycan expressed by epithelial and fibroblastic cells.

P09683	SECR_HUMAN	Secretin	11060443	Human secretin (SCT): gene structure, chromosome location, and distribution of mRNA.

Q8N6T7	SIRT6_HUMAN	NAD-dependent deacetylase sirtuin-6	18337721	SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin.

Q06346	YD367_YEAST	UPF0596 Golgi apparatus membrane protein YDR367W	14562095	Global analysis of protein localization in budding yeast.

P35189	TAF14_YEAST	Transcription initiation factor TFIID subunit 14	12138208	Molecular characterization of Saccharomyces cerevisiae TFIID.

Q9N2M8	HDC_DROME	Headcase protein	8575315	Headcase, an imaginal specific gene required for adult morphogenesis in Drosophila melanogaster.

Q9UJX5	APC4_HUMAN	Anaphase-promoting complex subunit 4	18485873	Mechanism of ubiquitin-chain formation by the human anaphase- promoting complex.

Q99986	VRK1_HUMAN	Serine/threonine-protein kinase VRK1	10951572	The human vaccinia-related kinase 1 (VRK1) phosphorylates threonine- 18 within the mdm-2 binding site of the p53 tumour suppressor protein.

Q9BXF3	CECR2_HUMAN	Cat eye syndrome critical region protein 2	11827465	Sequence analysis of LRPPRC and its SEC1 domain interaction partners suggests roles in cytoskeletal organization, vesicular trafficking, nucleocytosolic shuttling, and chromosome activity.

P50582	HSK1_SCHPO	Cell cycle serine/threonine-protein kinase hsk1	9705352	Purification of Hsk1, a minichromosome maintenance protein kinase from fission yeast.

Q03351	NTRK3_RAT	NT-3 growth factor receptor	15167895	A unique pathway for sustained neurotrophin signaling through an ankyrin-rich membrane-spanning protein.

Q8K458	PKR2_MOUSE	Prokineticin receptor 2	12024206	Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus.

Q9PUQ1	ETV4_DANRE	ETS translocation variant 4	9671318	Molecular characterization of the zebrafish PEA3 ETS-domain transcription factor.

O82663	DHSA1_ARATH	Succinate dehydrogenase [ubiquinone] flavoprotein subunit 1, mitochondrial	12374303	The four subunits of mitochondrial respiratory complex II are encoded by multiple nuclear genes and targeted to mitochondria in Arabidopsis thaliana.

O73715	LDB1A_DANRE	LIM domain-binding protein 1-A	16815859	Spliced isoforms of LIM-domain-binding protein (CLIM/NLI/Ldb) lacking the LIM-interaction domain.

P43687	HMX2_MOUSE	Homeobox protein HMX2	15363417	Hmx2 and Hmx3 homeobox genes direct development of the murine inner ear and hypothalamus and can be functionally replaced by Drosophila Hmx.

P22392	NDKB_HUMAN	Nucleoside diphosphate kinase B	8392752	Human c-myc transcription factor PuF identified as nm23-H2 nucleoside diphosphate kinase, a candidate suppressor of tumor metastasis.

Q64604	PTPRF_RAT	Receptor-type tyrosine-protein phosphatase F	8068021	Molecular cloning and expression of a unique receptor-like protein- tyrosine-phosphatase in the leucocyte-common-antigen-related phosphate family.

Q13526	PIN1_HUMAN	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	8606777	A human peptidyl-prolyl isomerase essential for regulation of mitosis.

Q05397	FAK1_HUMAN	Focal adhesion kinase 1	9756887	Interaction of Hic-5, A senescence-related protein, with focal adhesion kinase.

Q9H410	DSN1_HUMAN	Kinetochore-associated protein DSN1 homolog	16585270	The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation.

Q91YR1	TWF1_MOUSE	Twinfilin-1	9249064	Cloning and characterization of the mouse homolog of the human A6 gene.

P18124	RL7_HUMAN	60S ribosomal protein L7	8360149	Identification of a transcript that is down-regulated in senescent human fibroblasts. Cloning, sequence analysis, and regulation of the human L7 ribosomal protein gene.

Q92783	STAM1_HUMAN	Signal transducing adapter molecule 1	10383417	Possible involvement of a novel STAM-associated molecule 'AMSH' in intracellular signal transduction mediated by cytokines.

P18117	THBA_XENLA	Thyroid hormone receptor beta-A	15590892	In vitro and in vivo analysis of the thyroid disrupting activities of phenolic and phenol compounds in Xenopus laevis.

P53959	COG6_YEAST	Conserved oligomeric Golgi complex subunit 6	11703943	The Sec34/35 Golgi transport complex is related to the exocyst, defining a family of complexes involved in multiple steps of membrane traffic.

Q923B6	STEA4_MOUSE	Metalloreductase STEAP4	14988015	Interleukin-6 is a positive regulator of tumor necrosis factor alpha- induced adipose-related protein in 3T3-L1 adipocytes.

P18119	THBB_XENLA	Thyroid hormone receptor beta-B	2402492	Xenopus laevis alpha and beta thyroid hormone receptors.

P43115	PE2R3_HUMAN	Prostaglandin E2 receptor EP3 subtype	8307176	Cloning and expression of three isoforms of the human EP3 prostanoid receptor.

P38289	DEM1_YEAST	Defects in morphology protein 1, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

P49598	P2C37_ARATH	Protein phosphatase 2C 37	11181729	The AKT3 potassium channel protein interacts with the AtPP2CA protein phosphatase 2C.

P63170	DYL1_RAT	Dynein light chain 1, cytoplasmic	8702622	Brain cytoplasmic and flagellar outer arm dyneins share a highly conserved Mr 8,000 light chain.

Q9USQ0	SPO7_SCHPO	Sporulation-specific protein spo7	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UMX2	OAZ3_HUMAN	Ornithine decarboxylase antizyme 3	10781085	Discovery of a spermatogenesis stage-specific ornithine decarboxylase antizyme: antizyme 3.

Q9Y5E5	PCDB4_HUMAN	Protocadherin beta-4	10380929	A striking organization of a large family of human neural cadherin- like cell adhesion genes.

O15547	P2RX6_HUMAN	P2X purinoceptor 6	9242461	Cloning of P2XM, a novel human P2X receptor gene regulated by p53.

Q9H0Z9	RBM38_HUMAN	RNA-binding protein 38	19285943	ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing.

P33520	RES1_SCHPO	Cell division cycle-related protein res1/sct1	7916653	Sct1 functions in partnership with Cdc10 in a transcription complex that activates cell cycle START and inhibits differentiation.

Q02223	TNR17_HUMAN	Tumor necrosis factor receptor superfamily member 17	10908663	B cell maturation protein is a receptor for the tumor necrosis factor family member TALL-1.

Q9VMA3	CUP_DROME	Protein cup	14723848	Drosophila Cup is an eIF4E binding protein that associates with Bruno and regulates oskar mRNA translation in oogenesis.

Q9Y5S9	RBM8A_HUMAN	RNA-binding protein 8A	19410547	Disassembly of exon junction complexes by PYM.

Q9NXR7	BRE_HUMAN	BRCA1-A complex subunit BRE	11676476	Expression of human BRE in multiple isoforms.

Q9URY3	YLOH_SCHPO	TBC domain-containing protein C1952.17c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P97838	DLGP3_RAT	Disks large-associated protein 3	9115257	SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density.

P22792	CPN2_HUMAN	Carboxypeptidase N subunit 2	2378615	The deduced protein sequence of the human carboxypeptidase N high molecular weight subunit reveals the presence of leucine-rich tandem repeats.

Q1G1A4	LAS1_ARATH	Lanosterol synthase	16445886	Lanosterol biosynthesis in plants.

Q9FG87	KCS19_ARATH	3-ketoacyl-CoA synthase 19	15277688	Specific and differential inhibition of very-long-chain fatty acid elongases from Arabidopsis thaliana by different herbicides.

P48995	TRPC1_HUMAN	Short transient receptor potential channel 1	8663995	Cloning and functional expression of a human Ca2+-permeable cation channel activated by calcium store depletion.

Q9M0U9	SKI19_ARATH	F-box protein SKIP19	12795696	Protein interaction analysis of SCF ubiquitin E3 ligase subunits from Arabidopsis.

Q9H4A6	GOLP3_HUMAN	Golgi phosphoprotein 3	16263763	MIDAS/GPP34, a nuclear gene product, regulates total mitochondrial mass in response to mitochondrial dysfunction.

P47006	RPA34_YEAST	DNA-directed RNA polymerase I subunit RPA34	9121426	A34.5, a nonessential component of yeast RNA polymerase I, cooperates with subunit A14 and DNA topoisomerase I to produce a functional rRNA synthesis machine.

Q66GP9	NOS1_ARATH	Nitric oxide synthase 1	14526079	Identification of a plant nitric oxide synthase gene involved in hormonal signaling.

Q06688	SRR1L_YEAST	SRR1-like protein BER1	14562095	Global analysis of protein localization in budding yeast.

Q96EG1	ARSG_HUMAN	Arylsulfatase G	18283100	Arylsulfatase G, a novel lysosomal sulfatase.

Q07020	RL18_HUMAN	60S ribosomal protein L18	8218404	Nucleotide and deduced amino acid sequence of human ribosomal protein L18.

P41240	CSK_HUMAN	Tyrosine-protein kinase CSK	10790433	Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation.

Q9LRR7	NCED3_ARATH	9-cis-epoxycarotenoid dioxygenase NCED3, chloroplastic	12834401	Molecular characterization of the Arabidopsis 9-cis epoxycarotenoid dioxygenase gene family.

P38838	WSS1_YEAST	DNA damage response protein WSS1	15598824	Coordinated functions of WSS1, PSY2 and TOF1 in the DNA damage response.

Q9ZU25	MPPA1_ARATH	Probable mitochondrial-processing peptidase subunit alpha-1	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q8VIM4	BSND_MOUSE	Barttin	11734858	Barttin is a Cl- channel beta-subunit crucial for renal Cl- reabsorption and inner ear K+ secretion.

Q9NRM7	LATS2_HUMAN	Serine/threonine-protein kinase LATS2	18158288	Tumor suppressor LATS1 is a negative regulator of oncogene YAP.

Q09733	GEF2_SCHPO	Rho guanine nucleotide exchange factor gef2	14637153	Role of guanine nucleotide exchange factors for Rho family GTPases in the regulation of cell morphology and actin cytoskeleton in fission yeast.

P38340	NTM1_YEAST	Alpha N-terminal protein methyltransferase 1	14562095	Global analysis of protein localization in budding yeast.

O80338	EF101_ARATH	Ethylene-responsive transcription factor 2	10715325	Arabidopsis ethylene responsive element binding factors act as transcriptional activators or repressors of GCC box mediated gene expression.

P32572	SPS18_YEAST	Sporulation protein SPS18	7969036	Identification of a sporulation-specific promoter regulating divergent transcription of two novel sporulation genes in Saccharomyces cerevisiae.

P35613	BASI_HUMAN	Basigin	9767135	Characterization of the gene for human EMMPRIN, a tumor cell surface inducer of matrix metalloproteinases.

O94979	SC31A_HUMAN	Protein transport protein Sec31A	10788476	Mammalian homologues of yeast sec31p. An ubiquitously expressed form is localized to endoplasmic reticulum (ER) exit sites and is essential for ER-Golgi transport.

Q9UKK9	NUDT5_HUMAN	ADP-sugar pyrophosphatase	18462755	Molecular mechanism of ADP-ribose hydrolysis by human NUDT5 from structural and kinetic studies.

P91938	TRXR1_DROME	Thioredoxin reductase 1, mitochondrial	11158675	Substitution of the thioredoxin system for glutathione reductase in Drosophila melanogaster.

Q24338	ESC_DROME	Polycomb protein esc	10757791	A Drosophila ESC-E(Z) protein complex is distinct from other polycomb group complexes and contains covalently modified ESC.

Q64264	5HT1A_MOUSE	5-hydroxytryptamine receptor 1A	8254366	Cloning and differentiation-induced expression of a murine serotonin 1A receptor in a septal cell line.

O70127	ABCBB_RAT	Bile salt export pump	9545351	The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver.

Q969J5	I22R2_HUMAN	Interleukin-22 receptor subunit alpha-2	11390454	Identification, cloning, and characterization of a novel soluble receptor that binds IL-22 and neutralizes its activity.

P69423	TATC_ECOLI	Sec-independent protein translocase protein tatC	11867724	Rapid topology mapping of Escherichia coli inner-membrane proteins by prediction and PhoA/GFP fusion analysis.

Q9V3L1	NDST_DROME	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase	10433902	Heparan sulfate proteoglycans are essential for FGF receptor signaling during Drosophila embryonic development.

Q9P7V6	VPS33_SCHPO	Vacuolar protein sorting-associated protein 33	12868054	Characterization of vps33+, a gene required for vacuolar biogenesis and protein sorting in Schizosaccharomyces pombe.

Q08647	PUS7_YEAST	Multisubstrate pseudouridine synthase 7	12682021	Pseudouridylation (Psi) of U2 snRNA in S. cerevisiae is catalyzed by an RNA-independent mechanism.

Q9NJ98	BGBP1_MANSE	Beta-1,3-glucan-binding protein 1	10713054	A beta1,3-glucan recognition protein from an insect, Manduca sexta, agglutinates microorganisms and activates the phenoloxidase cascade.

Q9BYU1	PBX4_HUMAN	Pre-B-cell leukemia transcription factor 4	11335119	Pbx4, a new Pbx family member on mouse chromosome 8 is expressed during spermatogenesis.

Q9Y471	CMAH_HUMAN	Putative cytidine monophosphate-N-acetylneuraminic acid hydroxylase-like protein	9751737	A mutation in human CMP-sialic acid hydroxylase occurred after the Homo-Pan divergence.

Q9QYE9	PKHB1_MOUSE	Pleckstrin homology domain-containing family B member 1	15976448	PHR1, an integral membrane protein of the inner ear sensory cells, directly interacts with myosin 1c and myosin VIIa.

Q9JJW1	TSN2_RAT	Tetraspanin-2	10582623	A novel rat tetraspan protein in cells of the oligodendrocyte lineage.

Q99801	NKX31_HUMAN	Homeobox protein Nkx-3.1	9537602	Isolation and androgen regulation of the human homeobox cDNA, NKX3.1.

P40348	RFC2_YEAST	Replication factor C subunit 2	8202350	The RFC2 gene encoding a subunit of replication factor C of Saccharomyces cerevisiae.

Q9VF89	RM09_DROME	39S ribosomal protein L9, mitochondrial	11279069	Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria.

Q9BZV3	IMPG2_HUMAN	Interphotoreceptor matrix proteoglycan 2	10702256	SPACRCAN, a novel human interphotoreceptor matrix hyaluronan-binding proteoglycan synthesized by photoreceptors and pinealocytes.

Q99344	UBA3_YEAST	NEDD8-activating enzyme E1 catalytic subunit	9545234	A novel protein modification pathway related to the ubiquitin system.

Q14209	E2F2_HUMAN	Transcription factor E2F2	16360038	Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release.

Q9SIU2	NCBP1_ARATH	Nuclear cap-binding protein subunit 1	11525733	An mRNA cap binding protein, ABH1, modulates early abscisic acid signal transduction in Arabidopsis.

Q9NV92	NFIP2_HUMAN	NEDD4 family-interacting protein 2	12796489	Cloning and characterization of N4WBP5A, an inducible, cyclosporine- sensitive, Nedd4-binding protein in human T lymphocytes.

Q9LVG4	APRR3_ARATH	Two-component response regulator-like APRR3	18055606	PRR3 Is a vascular regulator of TOC1 stability in the Arabidopsis circadian clock.

P02461	CO3A1_HUMAN	Collagen alpha-1(III) chain	9036918	Mutations in the COL3A1 gene result in the Ehlers-Danlos syndrome type IV and alterations in the size and distribution of the major collagen fibrils of the dermis.

P78406	RAE1L_HUMAN	mRNA export factor	9370289	The human RAE1 gene is a functional homologue of Schizosaccharomyces pombe rae1 gene involved in nuclear export of poly(A)+ RNA.

P46776	RL27A_HUMAN	60S ribosomal protein L27a	7772601	Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs.

P01033	TIMP1_HUMAN	Metalloproteinase inhibitor 1	1653055	The cytokine-protease connection: identification of a 96-kD THP-1 gelatinase and regulation by interleukin-1 and cytokine inducers.

P23871	HEMH_ECOLI	Ferrochelatase	8458858	The Escherichia coli visA gene encodes ferrochelatase, the final enzyme of the heme biosynthetic pathway.

Q9EQH2	ERAP1_MOUSE	Endoplasmic reticulum aminopeptidase 1	11964289	A mouse orthologue of puromycin-insensitive leucyl-specific aminopeptidase is expressed in endothelial cells and plays an important role in angiogenesis.

P04040	CATA_HUMAN	Catalase	10656833	Active and inhibited human catalase structures: ligand and NADPH binding and catalytic mechanism.

P27487	DPP4_HUMAN	Dipeptidyl peptidase 4	11772392	Regulation of epithelial and lymphocyte cell adhesion by adenosine deaminase-CD26 interaction.

Q8BWD2	IP6K3_MOUSE	Inositol hexakisphosphate kinase 3	11502751	Identification and characterization of a novel inositol hexakisphosphate kinase.

O60264	SMCA5_HUMAN	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5	12972596	Functional analysis of the subunits of the chromatin assembly factor RSF.

P47054	NU192_YEAST	Nucleoporin NUP192	10428845	Nup192p is a conserved nucleoporin with a preferential location at the inner site of the nuclear membrane.

Q8CBD1	NRIP1_MOUSE	Nuclear receptor-interacting protein 1	11100122	The nuclear receptor co-repressor Nrip1 (RIP140) is essential for female fertility.

P22768	ASSY_YEAST	Argininosuccinate synthase	2897249	Arginine repression of the Saccharomyces cerevisiae ARG1 gene. Comparison of the ARG1 and ARG3 control regions.

P97480	EYA3_MOUSE	Eyes absent homolog 3	14628042	Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis.

Q8GYD9	SDE3_ARATH	Probable RNA helicase SDE3	11296239	SDE3 encodes an RNA helicase required for post-transcriptional gene silencing in Arabidopsis.

P43616	DUG1_YEAST	Cys-Gly metallodipeptidase DUG1	14562095	Global analysis of protein localization in budding yeast.

Q38961	SNM1_ARATH	DNA cross-link repair protein SNM1	15448639	SNM-dependent recombinational repair of oxidatively induced DNA damage in Arabidopsis thaliana.

P39923	NPR2_YEAST	Nitrogen permease regulator 2	7867803	A second nitrogen permease regulator in Saccharomyces cerevisiae.

O81242	RHL1_ARATH	DNA-binding protein RHL1	17951446	MIDGET unravels functions of the Arabidopsis topoisomerase VI complex in DNA endoreduplication, chromatin condensation, and transcriptional silencing.

P05708	HXK1_RAT	Hexokinase-1	9665168	The structure of mammalian hexokinase-1.

Q06214	JIP5_YEAST	WD repeat-containing protein JIP5	14562095	Global analysis of protein localization in budding yeast.

Q8BUZ1	ABRA_MOUSE	Actin-binding Rho-activating protein	11983702	STARS, a striated muscle activator of Rho signaling and serum response factor-dependent transcription.

P25604	STP22_YEAST	Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease	17442384	Molecular architecture and functional model of the complete yeast ESCRT-I heterotetramer.

Q01083	SPITZ_DROME	Protein spitz	11672524	Regulated intracellular ligand transport and proteolysis control EGF signal activation in Drosophila.

Q683C9	AUR2_ARATH	Serine/threonine-protein kinase Aurora-2	16028112	Characterization of plant Aurora kinases during mitosis.

Q9GYV9	MED7_DROME	Mediator of RNA polymerase II transcription subunit 7	16751183	Coactivator cross-talk specifies transcriptional output.

Q9UTG2	PUB2_SCHPO	E3 ubiquitin-protein ligase pub2	11956316	The novel HECT-type ubiquitin-protein ligase Pub2p shares partially overlapping function with Pub1p in Schizosaccharomyces pombe.

Q8WZ42	TITIN_HUMAN	Titin	11846417	Titin mutations as the molecular basis for dilated cardiomyopathy.

P13053	VDR_RAT	Vitamin D3 receptor	2829212	Isolation and expression of rat 1,25-dihydroxyvitamin D3 receptor cDNA.

P22057	PTGDS_RAT	Prostaglandin-H2 D-isomerase	7836410	Structural and functional significance of cysteine residues of glutathione-independent prostaglandin D synthase. Identification of Cys65 as an essential thiol.

Q03691	ROT1_YEAST	Protein ROT1	16567426	Saccharomyces cerevisiae Rot1p is an ER-localized membrane protein that may function with BiP/Kar2p in protein folding.

Q91XE0	GLYAT_MOUSE	Glycine N-acyltransferase	14651853	Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.

Q9ESN6	TRIM2_MOUSE	Tripartite motif-containing protein 2	11432975	Molecular cloning and characterization of neural activity-related RING finger protein (NARF): a new member of the RBCC family is a candidate for the partner of myosin V.

Q15822	ACHA2_HUMAN	Neuronal acetylcholine receptor subunit alpha-2	8906617	Comparative structure of human neuronal alpha 2-alpha 7 and beta 2- beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits.

P47033	PRY3_YEAST	Cell wall protein PRY3	15781460	Comprehensive proteomic analysis of Saccharomyces cerevisiae cell walls: identification of proteins covalently attached via glycosylphosphatidylinositol remnants or mild alkali-sensitive linkages.

O74563	BRL2_SCHPO	E3 ubiquitin-protein ligase brl2	17363370	HULC, a histone H2B ubiquitinating complex, modulates heterochromatin independent of histone methylation in fission yeast.

A4Q9F1	TTLL8_MOUSE	Protein monoglycylase TTLL8	19524510	Evolutionary divergence of enzymatic mechanisms for posttranslational polyglycylation.

Q9NRY2	SOSSC_HUMAN	SOSS complex subunit C	19605351	hSSB1 and hSSB2 form similar multiprotein complexes that participate in DNA damage response.

O95965	ITGBL_HUMAN	Integrin beta-like protein 1	10051402	Cloning and characterization of a novel beta integrin-related cDNA coding for the protein TIED ('ten beta integrin EGF-like repeat domains') that maps to chromosome band 13q33: a divergent stand-alone integrin stalk structure.

O35664	INAR2_MOUSE	Interferon alpha/beta receptor 2	9295335	Cloning and characterization of soluble and transmembrane isoforms of a novel component of the murine type I interferon receptor, IFNAR 2.

P84263	DAH12_LITDA	Dahlein-1.2	11555873	Bioactive dahlein peptides from the skin secretions of the Australian aquatic frog Litoria dahlii: sequence determination by electrospray mass spectrometry.

Q9UTK2	RM19_SCHPO	60S ribosomal protein L19, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P40065	MAM1_YEAST	Monopolin complex subunit MAM1	12689592	Kinetochore recruitment of two nucleolar proteins is required for homolog segregation in meiosis I.

Q15392	DHC24_HUMAN	24-dehydrocholesterol reductase	11007892	The human DIMINUTO/DWARF1 homolog seladin-1 confers resistance to Alzheimer's disease-associated neurodegeneration and oxidative stress.

Q06338	BCP1_YEAST	Protein BCP1	14562095	Global analysis of protein localization in budding yeast.

Q9BWW7	SCRT1_HUMAN	Transcriptional repressor scratch 1	11274425	Mammalian scratch: a neural-specific snail family transcriptional repressor.

P97477	STK6_MOUSE	Serine/threonine-protein kinase 6	15793587	Chfr is required for tumor suppression and Aurora A regulation.

Q21227	APR1_CAEEL	Adenomatous polyposis coli protein-related protein 1	11560894	The divergent Caenorhabditis elegans beta-catenin proteins BAR-1, WRM-1 and HMP-2 make distinct protein interactions but retain functional redundancy in vivo.

P25772	LIGB_ECOLI	DNA ligase B	11812821	A second NAD(+)-dependent DNA ligase (LigB) in Escherichia coli.

Q10322	DMA1_SCHPO	Probable E3 ubiquitin-protein ligase dma1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q6PVZ1	K1C14_CHICK	Keratin, type I cytoskeletal 14	15157236	Serial cultivation of chicken keratinocytes, a composite cell type that accumulates lipids and synthesizes a novel beta-keratin.

Q8WYL5	SSH1_HUMAN	Protein phosphatase Slingshot homolog 1	11832213	Control of actin reorganization by Slingshot, a family of phosphatases that dephosphorylate ADF/cofilin.

P23642	VAN1_YEAST	Mannan polymerase I complex VAN1 subunit	9430634	Multi-protein complexes in the cis Golgi of Saccharomyces cerevisiae with alpha-1,6-mannosyltransferase activity.

Q96253	ATP5E_ARATH	ATP synthase subunit epsilon, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q96SN7	ORAI2_HUMAN	Protein orai-2	20418871	A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cells.

Q9ERU3	ZNF22_MOUSE	Zinc finger protein 22	12489153	Krox-26 is a novel C2H2 zinc finger transcription factor expressed in developing dental and osteogenic tissues.

P97431	IRF6_MOUSE	Interferon regulatory factor 6	18212048	Interferon regulatory factor 6 promotes cell cycle arrest and is regulated by the proteasome in a cell cycle-dependent manner.

Q9P4U6	TCSB_EMENI	Two-component system protein B	12406718	Isolation and functional analysis of a gene, tcsB, encoding a transmembrane hybrid-type histidine kinase from Aspergillus nidulans.

Q9VQU9	BOWEL_DROME	Protein bowel	14597202	The odd-skipped family of zinc finger genes promotes Drosophila leg segmentation.

Q9H3D4	P63_HUMAN	Tumor protein 63	11641404	The p53 family member genes are involved in the Notch signal pathway.

O93827	MPG1_CANAL	Mannose-1-phosphate guanyltransferase	10913825	The VIG9 gene products from the human pathogenic fungi Candida albicans and Candida glabrata encode GDP-mannose pyrophosphorylase.

Q2WG80	RIPP1_DANRE	Protein ripply1	16326386	Groucho-associated transcriptional repressor ripply1 is required for proper transition from the presomitic mesoderm to somites.

P38925	SMF1_YEAST	Manganese transporter SMF1	10930410	The family of SMF metal ion transporters in yeast cells.

P53365	ARFP2_HUMAN	Arfaptin-2	8670882	Identification of a novel Rac1-interacting protein involved in membrane ruffling.

Q99942	RNF5_HUMAN	E3 ubiquitin-protein ligase RNF5	19269966	Regulation of endoplasmic reticulum-associated degradation by RNF5- dependent ubiquitination of JNK-associated membrane protein (JAMP).

O88470	FOXL2_MOUSE	Forkhead box protein L2	16153597	Transcriptional factor FOXL2 interacts with DP103 and induces apoptosis.

Q92973	TNPO1_HUMAN	Transportin-1	8808633	A novel receptor-mediated nuclear protein import pathway.

Q8R1H0	HOP_MOUSE	Homeodomain-only protein	12297045	Hop is an unusual homeobox gene that modulates cardiac development.

Q6NSN2	AOF_DANRE	Amine oxidase [flavin-containing]	15621520	Molecular characterization of monoamine oxidase in zebrafish (Danio rerio).

Q9FN69	GL3_ARATH	Transcription factor GLABRA 3	12917293	A network of redundant bHLH proteins functions in all TTG1-dependent pathways of Arabidopsis.

P53251	SLX9_YEAST	Ribosome biogenesis protein SLX9	17018574	Slx9p facilitates efficient ITS1 processing of pre-rRNA in Saccharomyces cerevisiae.

P45593	COF1B_XENLA	Cofilin-1-B	8603919	Xenopus laevis actin-depolymerizing factor/cofilin: a phosphorylation-regulated protein essential for development.

P54848	EMP1_RAT	Epithelial membrane protein 1	7499407	Epithelial membrane protein-1, peripheral myelin protein 22, and lens membrane protein 20 define a novel gene family.

Q8GX78	ANTR2_ARATH	Probable anion transporter 2, chloroplastic	18086223	Functional analysis of the Arabidopsis PHT4 family of intracellular phosphate transporters.

Q94AZ2	STP13_ARATH	Sugar transport protein 13	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q99PU7	BAP1_MOUSE	Ubiquitin carboxyl-terminal hydrolase BAP1	9528852	BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression.

P32489	MEI5_YEAST	Meiosis protein 5	15620352	A protein complex containing Mei5 and Sae3 promotes the assembly of the meiosis-specific RecA homolog Dmc1.

Q8GSA7	CMTA3_ARATH	Calmodulin-binding transcription activator 3	12218065	A calmodulin-binding/CGCG box DNA-binding protein family involved in multiple signaling pathways in plants.

Q9P775	YBEG_SCHPO	Uncharacterized WD repeat-containing protein C17D11.16	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P54900	SCN2B_RAT	Sodium channel subunit beta-2	8521473	Structure and function of the beta 2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM motif.

O42658	PHS_SCHPO	Pterin-4-alpha-carbinolamine dehydratase	12786945	Overlapping omt1+ and omt2+ genes are required for spore wall maturation in Schizosaccharomyces pombe.

Q9Y5F2	PCDBB_HUMAN	Protocadherin beta-11	10380929	A striking organization of a large family of human neural cadherin- like cell adhesion genes.

P49911	AN32A_RAT	Acidic leucine-rich nuclear phosphoprotein 32 family member A	15895553	The Anp32 family of proteins containing leucine-rich repeats.

P10415	BCL2_HUMAN	Apoptosis regulator Bcl-2	11463391	PUMA induces the rapid apoptosis of colorectal cancer cells.

P35557	HXK4_HUMAN	Glucokinase	8446612	Glucokinase mutations associated with non-insulin-dependent (type 2) diabetes mellitus have decreased enzymatic activity: implications for structure/function relationships.

P38615	RIM11_YEAST	Serine/threonine-protein kinase RIM11/MSD1	10679022	Essential functions of protein tyrosine phosphatases PTP2 and PTP3 and RIM11 tyrosine phosphorylation in Saccharomyces cerevisiae meiosis and sporulation.

Q9ES38	S27A5_RAT	Bile acyl-CoA synthetase	12454267	Molecular cloning and expression of rat liver bile acid CoA ligase.

P28749	RBL1_HUMAN	Retinoblastoma-like protein 1	16360038	Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release.

O94599	YC8B_SCHPO	LIMR family protein C622.11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q19691	TBX2_CAEEL	T-box protein 2	16701625	The T-box factor TBX-2 and the SUMO conjugating enzyme UBC-9 are required for ABa-derived pharyngeal muscle in C. elegans.

P58462	FOXP1_MOUSE	Forkhead box protein P1	14701752	Transcriptional and DNA binding activity of the Foxp1/2/4 family is modulated by heterotypic and homotypic protein interactions.

Q9Y3D5	RT18C_HUMAN	28S ribosomal protein S18c, mitochondrial	11279123	The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present.

P40897	OPT1_YEAST	Oligopeptide transporter 1	10652283	Enkephalins are transported by a novel eukaryotic peptide uptake system.

P31323	KAP3_HUMAN	cAMP-dependent protein kinase type II-beta regulatory subunit	2851102	Molecular cloning, complementary deoxyribonucleic acid structure and predicted full-length amino acid sequence of the hormone-inducible regulatory subunit of 3'-5'-cyclic adenosine monophosphate-dependent protein kinase from human testis.

Q9SZF7	SHR_ARATH	Protein SHORT-ROOT	11565032	Intercellular movement of the putative transcription factor SHR in root patterning.

O74465	HRR1_SCHPO	Helicase required for RNAi-mediated heterochromatin assembly 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P58215	LOXL3_HUMAN	Lysyl oxidase homolog 3	11284725	Cloning and characterization of a fourth human lysyl oxidase isoenzyme.

Q03497	STE20_YEAST	Serine/threonine-protein kinase STE20	9003780	Functional analysis of the interaction between the small GTP binding protein Cdc42 and the Ste20 protein kinase in yeast.

Q04049	POLH_YEAST	DNA polymerase eta	9974380	Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Poleta.

Q24210	CAKI_DROME	Calcium/calmodulin-dependent protein kinase	8617233	A new Drosophila Ca2+/calmodulin-dependent protein kinase (Caki) is localized in the central nervous system and implicated in walking speed.

P40356	MED3_YEAST	Mediator of RNA polymerase II transcription subunit 3	10722672	Hrs1/Med3 is a Cyc8-Tup1 corepressor target in the RNA polymerase II holoenzyme.

Q60954	MEIS1_MOUSE	Homeobox protein Meis1	9315626	Meis proteins are major in vivo DNA binding partners for wild-type but not chimeric Pbx proteins.

P53123	MRM2_YEAST	Ribosomal RNA methyltransferase MRM2, mitochondrial	11867542	MRM2 encodes a novel yeast mitochondrial 21S rRNA methyltransferase.

P40581	GPX3_YEAST	Peroxiredoxin HYR1	11445588	Saccharomyces cerevisiae expresses three phospholipid hydroperoxide glutathione peroxidases.

Q9NP80	PLPL8_HUMAN	Calcium-independent phospholipase A2-gamma	10744668	The genomic organization, complete mRNA sequence, cloning, and expression of a novel human intracellular membrane-associated calcium- independent phospholipase A(2).

P28482	MK01_HUMAN	Mitogen-activated protein kinase 1	1540184	Extracellular signal-regulated kinases in T cells: characterization of human ERK1 and ERK2 cDNAs.

P31210	AK1D1_RAT	3-oxo-5-beta-steroid 4-dehydrogenase	1789929	Delta 4-3-Oxosteroid 5 beta-reductase. Structure and function.

Q12446	LAS17_YEAST	Proline-rich protein LAS17	10512884	The Saccharomyces cerevisiae homologue of human Wiskott-Aldrich syndrome protein Las17p interacts with the Arp2/3 complex.

O73798	IGF1R_XENLA	Insulin-like growth factor 1 receptor	9492024	Molecular cloning and characterization of Xenopus insulin-like growth factor-1 receptor: its role in mediating insulin-induced Xenopus oocyte maturation and expression during embryogenesis.

O88554	PARP2_MOUSE	Poly [ADP-ribose] polymerase 2	11948190	Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1.

P13726	TF_HUMAN	Tissue factor	8598903	The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor.

P63272	SPT4H_HUMAN	Transcription elongation factor SPT4	8649394	Identification and analysis of a functional human homolog of the SPT4 gene of Saccharomyces cerevisiae.

Q92905	CSN5_HUMAN	COP9 signalosome complex subunit 5	19214193	K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC- associated Brcc36 and proteasomal Poh1.

O14246	TPZ1_SCHPO	Protection of telomeres protein tpz1	18535244	Fission yeast Pot1-Tpp1 protects telomeres and regulates telomere length.

Q06668	OMS1_YEAST	Methyltransferase OMS1, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

P31321	KAP1_HUMAN	cAMP-dependent protein kinase type I-beta regulatory subunit	1708242	Molecular cloning, cDNA structure and tissue-specific expression of the human regulatory subunit RI beta of cAMP-dependent protein kinases.

P19525	E2AK2_HUMAN	Interferon-induced, double-stranded RNA-activated protein kinase	1695551	Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon.

P25625	PER1_YEAST	Protein PER1	17021251	PER1 is required for GPI-phospholipase A2 activity and involved in lipid remodeling of GPI-anchored proteins.

Q02248	CTNB1_MOUSE	Catenin beta-1	12874278	The PDZ protein tax-interacting protein-1 inhibits beta-catenin transcriptional activity and growth of colorectal cancer cells.

Q5SV77	GGNB2_MOUSE	Gametogenetin-binding protein 2	15642376	Yeast two-hybrid screens imply that GGNBP1, GGNBP2 and OAZ3 are potential interaction partners of testicular germ cell-specific protein GGN1.

Q8WVK7	SKA2_HUMAN	Spindle and kinetochore-associated protein 2	19289083	The human kinetochore Ska1 complex facilitates microtubule depolymerization-coupled motility.

P35250	RFC2_HUMAN	Replication factor C subunit 2	15655353	The second subunit of the replication factor C complex (RFC40) and the regulatory subunit (RIalpha) of protein kinase A form a protein complex promoting cell survival.

P85069	OJP3_SEPOF	Ovarian jelly-peptide 3	16434122	Ovarian jelly-peptides (OJPs), a new family of regulatory peptides identified in the cephalopod Sepia officinalis.

P33151	CADH5_HUMAN	Cadherin-5	9219219	Vascular endothelial cadherin (VE-cadherin): cloning and role in endothelial cell-cell adhesion.

P39109	YCFI_YEAST	Metal resistance protein YCF1	10790694	The products of YCF1 and YLL015w (BPT1) cooperate for the ATP- dependent vacuolar transport of unconjugated bilirubin in Saccharomyces cerevisiae.

Q92988	DLX4_HUMAN	Homeobox protein DLX-4	11069021	BP1, a new homeobox gene, is frequently expressed in acute leukemias.

Q03530	RCE1_YEAST	CAAX prenyl protease 2	9736709	Endoplasmic reticulum membrane localization of Rce1p and Ste24p, yeast proteases involved in carboxyl-terminal CAAX protein processing and amino-terminal a-factor cleavage.

P17719	DYR_DROME	Dihydrofolate reductase	2116172	The purification of dihydrofolate reductase from Drosophila melanogaster.

Q9UTH8	SFP1_SCHPO	Zinc finger protein sfp1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9XIW0	CIPK7_ARATH	CBL-interacting serine/threonine-protein kinase 7	11230129	The NAF domain defines a novel protein-protein interaction module conserved in Ca(2+)-regulated kinases.

P17405	ASM_HUMAN	Sphingomyelin phosphodiesterase	1718266	Molecular basis of acid sphingomyelinase deficiency in a patient with Niemann-Pick disease type A.

Q8INM9	GR85A_DROME	Putative gustatory receptor 85a	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

O42665	YF8B_SCHPO	Uncharacterized but2-like protein C27D7.11c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O14343	KLP5_SCHPO	Kinesin-like protein 5	11967147	Two kinesin-like Kin I family proteins in fission yeast regulate the establishment of metaphase and the onset of anaphase A.

Q75GK1	IAA12_ORYSJ	Auxin-responsive protein IAA12	16200395	Structure and expression analysis of early auxin-responsive Aux/IAA gene family in rice (Oryza sativa).

Q63180	ADAM7_RAT	Disintegrin and metalloproteinase domain-containing protein 7	1417724	A mammalian epididymal protein with remarkable sequence similarity to snake venom haemorrhagic peptides.

P53865	CNM67_YEAST	Chaotic nuclear migration protein 67	14515169	YOR129c, a new element interacting with Cnm67p, a component of the spindle pole body of Saccharomyces cerevisiae.

O43315	AQP9_HUMAN	Aquaporin-9	9514918	Cloning and functional expression of a new aquaporin (AQP9) abundantly expressed in the peripheral leukocytes permeable to water and urea, but not to glycerol.

Q9C0U7	VPS5_SCHPO	Vacuolar protein sorting-associated protein vps5	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P14550	AK1A1_HUMAN	Alcohol dehydrogenase [NADP+]	2498333	The aldo-keto reductase superfamily. cDNAs and deduced amino acid sequences of human aldehyde and aldose reductases.

Q9UUH3	MUG58_SCHPO	Uncharacterized kinase mug58	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9VQI9	AFF4_DROME	AF4/FMR2 family member 4	11171403	Lilliputian: an AF4/FMR2-related protein that controls cell identity and cell growth.

Q90X64	VNG2A_XENLA	Vang-like protein 2-A	11867525	The planar polarity gene strabismus regulates convergent extension movements in Xenopus.

Q16514	TAF12_HUMAN	Transcription initiation factor TFIID subunit 12	9674425	Histone-like TAFs within the PCAF histone acetylase complex.

Q99569	PKP4_HUMAN	Plakophilin-4	19706687	PDZ-domain-directed basolateral targeting of the peripheral membrane protein FRMPD2 in epithelial cells.

Q86TM6	SYVN1_HUMAN	E3 ubiquitin-protein ligase synoviolin	18264092	OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD.

P49454	CENPF_HUMAN	Centromere protein F	9763420	Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1.

Q03233	ADD37_YEAST	Alpha1-proteinase inhibitor-degradation deficient protein 37	14562095	Global analysis of protein localization in budding yeast.

O96935	AMP1_PLAFQ	M1 family aminopeptidase	9879894	A Plasmodium falciparum aminopeptidase gene belonging to the M1 family of zinc-metallopeptidases is expressed in erythrocytic stages.

Q9NZ53	PDXL2_HUMAN	Podocalyxin-like protein 2	10722749	Identification of endoglycan, a member of the CD34/podocalyxin family of sialomucins.

Q5DU02	UBP22_MOUSE	Ubiquitin carboxyl-terminal hydrolase 22	16378762	The expression patterns of deubiquitinating enzymes, USP22 and Usp22.

Q8TBC4	UBA3_HUMAN	NEDD8-activating enzyme E1 catalytic subunit	12740388	Conservation in the mechanism of Nedd8 activation by the human AppBp1-Uba3 heterodimer.

P39297	BSMA_ECOLI	Lipoprotein BsmA	19833773	A previously uncharacterized gene, yjfO (bsmA), influences Escherichia coli biofilm formation and stress response.

Q9ULW3	ABT1_HUMAN	Activator of basal transcription 1	10648625	A novel TATA-binding protein-binding protein, ABT1, activates basal transcription and has a yeast homolog that is essential for growth.

O35052	CDS1_RAT	Phosphatidate cytidylyltransferase 1	9083091	Gene cloning and characterization of CDP-diacylglycerol synthase from rat brain.

O94250	GLO22_SCHPO	Probable hydroxyacylglutathione hydrolase C13B11.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P22214	SEC22_YEAST	Protein transport protein SEC22	12853481	Use1p is a yeast SNARE protein required for retrograde traffic to the ER.

Q9S7V4	HA22A_ARATH	HVA22-like protein a	12081371	AtHVA22 gene family in Arabidopsis: phylogenetic relationship, ABA and stress regulation, and tissue-specific expression.

P49723	RIR4_YEAST	Ribonucleoside-diphosphate reductase small chain 2	10716984	Yeast ribonucleotide reductase has a heterodimeric iron-radical- containing subunit.

P53743	ESF2_YEAST	Pre-rRNA-processing protein ESF2	15964808	Esf2p, a U3-associated factor required for small-subunit processome assembly and compaction.

Q12906	ILF3_HUMAN	Interleukin enhancer-binding factor 3	10574923	Autoantibodies define a family of proteins with conserved double- stranded RNA-binding domains as well as DNA binding activity.

P15428	PGDH_HUMAN	15-hydroxyprostaglandin dehydrogenase [NAD+]	16828555	Role of glutamine 148 of human 15-hydroxyprostaglandin dehydrogenase in catalytic oxidation of prostaglandin E2.

P62318	SMD3_HUMAN	Small nuclear ribonucleoprotein Sm D3	17709427	Two distinct arginine methyltransferases are required for biogenesis of Sm-class ribonucleoproteins.

P30052	SCAL_DROME	Protein scalloped	18313299	SCALLOPED interacts with YORKIE, the nuclear effector of the hippo tumor-suppressor pathway in Drosophila.

O13782	FNTB_SCHPO	Protein farnesyltransferase subunit beta	10617635	Protein farnesylation is critical for maintaining normal cell morphology and canavanine resistance in Schizosaccharomyces pombe.

Q9BWF3	RBM4_HUMAN	RNA-binding protein 4	9169144	A novel zinc finger-containing RNA-binding protein conserved from fruitflies to humans.

Q9HB21	PKHA1_HUMAN	Pleckstrin homology domain-containing family A member 1	12101241	TAPP1 and TAPP2 are targets of phosphatidylinositol 3-kinase signaling in B cells: sustained plasma membrane recruitment triggered by the B-cell antigen receptor.

P36101	YKC7_YEAST	Uncharacterized protein YKL027W	16407407	Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins.

Q9Y4E1	FA21C_HUMAN	WASH complex subunit FAM21C	19922874	A FAM21-containing WASH complex regulates retromer-dependent sorting.

Q9UDY2	ZO2_HUMAN	Tight junction protein ZO-2	15975580	hScrib interacts with ZO-2 at the cell-cell junctions of epithelial cells.

P55853	SUMO_CAEEL	Small ubiquitin-related modifier	15107848	SUMO modification is required for in vivo Hox gene regulation by the Caenorhabditis elegans Polycomb group protein SOP-2.

P46309	GSH1_ARATH	Glutamate--cysteine ligase, chloroplastic	8090752	Isolation of phytoalexin-deficient mutants of Arabidopsis thaliana and characterization of their interactions with bacterial pathogens.

O94421	SNF22_SCHPO	SWI/SNF chromatin-remodeling complex subunit snf22	18622392	Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast.

Q96301	SPY_ARATH	Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY	12068105	SPINDLY is a nuclear-localized repressor of gibberellin signal transduction expressed throughout the plant.

Q9FNL7	PTR3_ARATH	Peptide transporter PTR3-A	15889294	Structural and functional characterization of AtPTR3, a stress- induced peptide transporter of Arabidopsis.

Q8W4M7	ERCC2_ARATH	DNA repair helicase UVH6	9414549	Evidence that heat and ultraviolet radiation activate a common stress-response program in plants that is altered in the uvh6 mutant of Arabidopsis thaliana.

Q9U405	GRAU_DROME	Transcription factor grauzone	10924478	The only function of Grauzone required for Drosophila oocyte meiosis is transcriptional activation of the cortex gene.

Q8CIV8	TBCE_MOUSE	Tubulin-specific chaperone E	12389029	A missense mutation in Tbce causes progressive motor neuronopathy in mice.

Q9BQ83	SLX1_HUMAN	Structure-specific endonuclease subunit SLX1	19596236	Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases.

Q9GZZ1	NAA50_HUMAN	N-alpha-acetyltransferase 50, NatE catalytic subunit	16507339	Cloning and characterization of hNAT5/hSAN: an evolutionarily conserved component of the NatA protein N-alpha-acetyltransferase complex.

P34216	EDE1_YEAST	EH domain-containing and endocytosis protein 1	11452010	A genomic study of the bipolar bud site selection pattern in Saccharomyces cerevisiae.

O95980	RECK_HUMAN	Reversion-inducing cysteine-rich protein with Kazal motifs	9789069	Regulation of matrix metalloproteinase-9 and inhibition of tumor invasion by the membrane-anchored glycoprotein RECK.

P01722	LV602_HUMAN	Ig lambda chain V-VI region NIG-48	118171	Comparative study on the structure of the light chains of human immunoglobulins. II. Assignment of a new subgroup.

Q9D256	ISK12_MOUSE	Serine protease inhibitor Kazal-type 12	16930550	Novel epididymal protease inhibitors with Kazal or WAP family domain.

O70343	PRGC1_MOUSE	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha	16950137	Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway.

Q03503	NAA30_YEAST	N-alpha-acetyltransferase 30, NatC catalytic subunit	11274203	NatC Nalpha-terminal acetyltransferase of yeast contains three subunits, Mak3p, Mak10p, and Mak31p.

Q498J7	MC6ZA_XENLA	Zygotic DNA replication licensing factor mcm6-A	9512418	Developmental regulation of MCM replication factors in Xenopus laevis.

O60637	TSN3_HUMAN	Tetraspanin-3	9714763	Sequences and expression of six new members of the tetraspanin/TM4SF family.

Q9UHJ9	PGAP2_HUMAN	Post-GPI attachment to proteins factor 2	10585768	Human FRAG1 encodes a novel membrane-spanning protein that localizes to chromosome 11p15.5, a region of frequent loss of heterozygosity in cancer.

P08096	TOP2_SCHPO	DNA topoisomerase 2	3023070	The nucleotide sequence of the fission yeast DNA topoisomerase II gene: structural and functional relationships to other DNA topoisomerases.

P24894	COX2_CAEEL	Cytochrome c oxidase subunit 2	1551572	The mitochondrial genomes of two nematodes, Caenorhabditis elegans and Ascaris suum.

Q03920	MTQ2_YEAST	eRF1 methyltransferase catalytic subunit MTQ2	17008308	The zinc finger protein Ynr046w is plurifunctional and a component of the eRF1 methyltransferase in yeast.

Q9BUN8	DERL1_HUMAN	Derlin-1	18675248	Ubiquitin ligase Kf-1 is involved in the endoplasmic reticulum- associated degradation pathway.

O76337	CED6_CAEEL	Cell death protein 6	9635426	Candidate adaptor protein CED-6 promotes the engulfment of apoptotic cells in C. elegans.

Q05901	ACHB3_HUMAN	Neuronal acetylcholine receptor subunit beta-3	7690916	Molecular cloning of a human neuronal nicotinic acetylcholine receptor beta 3-like subunit.

P32191	GPDM_YEAST	Glycerol-3-phosphate dehydrogenase, mitochondrial	11502169	Yeast mitochondrial dehydrogenases are associated in a supramolecular complex.

Q9Y4K3	TRAF6_HUMAN	TNF receptor-associated factor 6	14530355	Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3, in the Toll-like receptor signaling.

Q61045	SIM1_MOUSE	Single-minded homolog 1	9020169	Two murine homologs of the Drosophila single-minded protein that interact with the mouse aryl hydrocarbon receptor nuclear translocator protein.

Q92172	TEF_CHICK	Transcription factor VBP	1922023	Chicken vitellogenin gene-binding protein, a leucine zipper transcription factor that binds to an important control element in the chicken vitellogenin II promoter, is related to rat DBP.

Q9BXF6	RFIP5_HUMAN	Rab11 family-interacting protein 5	11278501	Gaf-1, a gamma-SNAP-binding protein associated with the mitochondria.

Q54GL7	MLCB_DICDI	Myosin-IB light chain	16415352	Identification and characterization of an 8-kDa light chain associated with Dictyostelium discoideum MyoB, a class I myosin.

P29965	CD40L_HUMAN	CD40 ligand	7678552	Human CD40-ligand: molecular cloning, cellular distribution and regulation of expression by factors controlling IgE production.

Q16512	PKN1_HUMAN	Serine/threonine-protein kinase N1	10619026	The structural basis of Rho effector recognition revealed by the crystal structure of human RhoA complexed with the effector domain of PKN/PRK1.

P16443	DBP_RAT	D site-binding protein	2331750	DBP, a liver-enriched transcriptional activator, is expressed late in ontogeny and its tissue specificity is determined posttranscriptionally.

Q9EST9	FGF20_RAT	Fibroblast growth factor 20	11032730	FGF-20, a novel neurotrophic factor, preferentially expressed in the substantia nigra pars compacta of rat brain.

O94697	RFC5_SCHPO	Replication factor C subunit 5	16040599	Contrasting effects of Elg1-RFC and Ctf18-RFC inactivation in the absence of fully functional RFC in fission yeast.

P0AG63	RS17_ECOLI	30S ribosomal protein S17	765484	Alteration of ribosomal protein S17 by mutation linked to neamine resistance in Escherichia coli. I. General properties of neaA mutants.

P97452	BOP1_MOUSE	Ribosome biogenesis protein BOP1	10891491	Bop1 is a mouse WD40 repeat nucleolar protein involved in 28S and 5. 8S rRNA processing and 60S ribosome biogenesis.

Q6VVX0	CP2R1_HUMAN	Vitamin D 25-hydroxylase	15465040	Metabolism of vitamin D by human microsomal CYP2R1.

P50552	VASP_HUMAN	Vasodilator-stimulated phosphoprotein	17914456	Structural basis for the recruitment of profilin-actin complexes during filament elongation by Ena/VASP.

O95477	ABCA1_HUMAN	ATP-binding cassette sub-family A member 1	10431236	Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency.

P38182	ATG8_YEAST	Autophagy-related protein 8	11689437	The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation.

Q9ZWJ9	ARR2_ARATH	Two-component response regulator ARR2	11370868	The response regulator ARR2: a pollen-specific transcription factor involved in the expression of nuclear genes for components of mitochondrial complex I in Arabidopsis.

P42286	THR_DROME	Protein three rows	9927461	Identification of genes controlling malpighian tubule and other epithelial morphogenesis in Drosophila melanogaster.

Q16763	UBE2S_HUMAN	Ubiquitin-conjugating enzyme E2 S	19820702	UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exit.

Q12246	LCB4_YEAST	Sphingoid long chain base kinase 4	11278643	Calcium influx and signaling in yeast stimulated by intracellular sphingosine 1-phosphate accumulation.

Q9ULB4	CADH9_HUMAN	Cadherin-9	10861224	Identification of three human type-II classic cadherins and frequent heterophilic interactions between different subclasses of type-II classic cadherins.

P48442	CASR_RAT	Extracellular calcium-sensing receptor	7816802	Cloning and functional expression of a rat kidney extracellular calcium/polyvalent cation-sensing receptor.

Q75HC2	AGO7_ORYSJ	Protein argonaute 7	17804793	The small interfering RNA production pathway is required for shoot meristem initiation in rice.

Q7RTV0	PHF5A_HUMAN	PHD finger-like domain-containing protein 5A	12234937	Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein.

P33303	SFC1_YEAST	Succinate/fumarate mitochondrial transporter	9395087	Identification of the yeast ACR1 gene product as a succinate-fumarate transporter essential for growth on ethanol or acetate.

Q8K1S5	KLF11_MOUSE	Krueppel-like factor 11	14697507	Gene structure and evolution of Tieg3, a new member of the Tieg family of proteins.

P25655	NOT1_YEAST	General negative regulator of transcription subunit 1	11889048	Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae.

P39000	SHC1_YEAST	Protein SHC1	15755916	Saccharomyces cerevisiae Sps1p regulates trafficking of enzymes required for spore wall synthesis.

O94663	SNF8_SCHPO	Vacuolar-sorting protein dot2	17660439	Essential roles of class E Vps proteins for sorting into multivesicular bodies in Schizosaccharomyces pombe.

Q9LUV1	PMEI2_ARATH	Pectinesterase inhibitor 2	14675772	Identification of pollen-expressed pectin methylesterase inhibitors in Arabidopsis.

P15807	MET8_YEAST	Siroheme biosynthesis protein MET8	10051442	The role of Saccharomyces cerevisiae Met1p and Met8p in sirohaem and cobalamin biosynthesis.

Q10428	2AD1_SCHPO	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta 1 isoform	10757751	Isolation and characterization of par1(+) and par2(+): two Schizosaccharomyces pombe genes encoding B' subunits of protein phosphatase 2A.

Q9H0E7	UBP44_HUMAN	Ubiquitin carboxyl-terminal hydrolase 44	20402667	K48- and K63-linked polyubiquitination of deubiquitinating enzyme USP44.

P40957	MAD1_YEAST	Spindle assembly checkpoint component MAD1	7593191	Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast.

Q8CDG1	PIWL2_MOUSE	Piwi-like protein 2	18404146	Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes.

Q9US10	YK68_SCHPO	Uncharacterized membrane protein C6F6.13c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9XJ36	CLPR2_ARATH	ATP-dependent Clp protease proteolytic subunit-related protein 2, chloroplastic	11278690	Identification of a 350-kDa ClpP protease complex with 10 different Clp isoforms in chloroplasts of Arabidopsis thaliana.

Q9C826	ABA2_ARATH	Xanthoxin dehydrogenase	9159947	Biochemical characterization of the aba2 and aba3 mutants in Arabidopsis thaliana.

Q8JGN5	BI51A_XENLA	Baculoviral IAP repeat-containing protein 5.1-A	18591255	A survivin-ran complex regulates spindle formation in tumor cells.

P49247	RPIA_HUMAN	Ribose-5-phosphate isomerase	14988808	Ribose-5-phosphate isomerase deficiency: new inborn error in the pentose phosphate pathway associated with a slowly progressive leukoencephalopathy.

Q16637	SMN_HUMAN	Survival motor neuron protein	8670859	A novel nuclear structure containing the survival of motor neurons protein.

P78337	PITX1_HUMAN	Pituitary homeobox 1	9070926	Backfoot, a novel homeobox gene, maps to human chromosome 5 (BFT) and mouse chromosome 13 (Bft).

P49917	DNLI4_HUMAN	DNA ligase 4	9809069	DNA ligase IV is essential for V(D)J recombination and DNA double- strand break repair in human precursor lymphocytes.

P41797	HSP71_CANAL	Heat shock protein SSA1	12761219	Candida albicans Ssa1/2p is the cell envelope binding protein for human salivary histatin 5.

P53323	BUD32_YEAST	Serine/threonine-protein kinase BUD32	16564010	A genome-wide screen identifies the evolutionarily conserved KEOPS complex as a telomere regulator.

Q00056	HXA4_HUMAN	Homeobox protein Hox-A4	1675427	Alteration of homeobox gene expression by N-ras transformation of PA- 1 human teratocarcinoma cells.

P46681	DLD2_YEAST	D-lactate dehydrogenase [cytochrome] 2, mitochondrial	10509019	Signalling between mitochondria and the nucleus regulates the expression of a new D-lactate dehydrogenase activity in yeast.

Q9XZT6	DNK_DROME	Deoxynucleoside kinase	9461577	Four deoxynucleoside kinase activities from Drosophila melanogaster are contained within a single monomeric enzyme, a new multifunctional deoxynucleoside kinase.

P32891	DLD1_YEAST	D-lactate dehydrogenase [cytochrome] 1, mitochondrial	8492799	Isolation of the DLD gene of Saccharomyces cerevisiae encoding the mitochondrial enzyme D-lactate ferricytochrome c oxidoreductase.

P25366	OCA4_YEAST	Protein OCA4	14562095	Global analysis of protein localization in budding yeast.

P06733	ENOA_HUMAN	Alpha-enolase	2005901	Cloning and characterization of a human c-myc promoter-binding protein.

Q9UQL6	HDAC5_HUMAN	Histone deacetylase 5	19666599	Human BAHD1 promotes heterochromatic gene silencing.

Q9Y7T6	YCJA_SCHPO	Uncharacterized membrane protein C63.10c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P46014	P2C70_ARATH	Protein phosphatase 2C 70	7973632	Interaction of a protein phosphatase with an Arabidopsis serine- threonine receptor kinase.

Q01860	PO5F1_HUMAN	POU domain, class 5, transcription factor 1	18191611	Pyruvate kinase isozyme type M2 (PKM2) interacts and cooperates with Oct-4 in regulating transcription.

Q16621	NFE2_HUMAN	Transcription factor NF-E2 45 kDa subunit	8355703	Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner.

P40151	WRIP1_YEAST	DNA-dependent ATPase MGS1	11459965	A yeast gene, MGS1, encoding a DNA-dependent AAA(+) ATPase is required to maintain genome stability.

Q9HBW0	LPAR2_HUMAN	Lysophosphatidic acid receptor 2	9525886	Characterization of a novel subtype of human G protein-coupled receptor for lysophosphatidic acid.

O44342	WBL_DROME	Protein windbeutel	11076773	Windbeutel is required for function and correct subcellular localization of the Drosophila patterning protein Pipe.

P62745	RHOB_HUMAN	Rho-related GTP-binding protein RhoB	3888408	A novel ras-related gene family.

P13423	PAG_BACAN	Protective antigen	14507921	Binding of anthrax toxin to its receptor is similar to alpha integrin-ligand interactions.

P36038	CBT1_YEAST	Cytochrome b termination protein 1	9339340	A novel nuclear gene, CBT1, essential for mitochondrial cytochrome b formation: terminal processing of mRNA and intron dependence.

Q9CQS7	DPA5A_MOUSE	Developmental pluripotency-associated protein 5A	16872451	Esg1, expressed exclusively in preimplantation embryos, germline, and embryonic stem cells, is a putative RNA-binding protein with broad RNA targets.

Q12511	PP2C5_YEAST	Protein phosphatase 2C homolog 5	16643908	YIL042c and YOR090c encode the kinase and phosphatase of the Saccharomyces cerevisiae pyruvate dehydrogenase complex.

O88551	CLD1_MOUSE	Claudin-1	9647647	Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin.

P40046	VTC1_YEAST	Vacuolar transporter chaperone 1	11102525	New components of a system for phosphate accumulation and polyphosphate metabolism in Saccharomyces cerevisiae revealed by genomic expression analysis.

O15061	SYNEM_HUMAN	Synemin	18342854	Identification of a repeated domain within mammalian alpha-synemin that interacts directly with talin.

Q1MTR2	RNPS1_SCHPO	RNA-binding protein with serine-rich domain 1 homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P02814	SMR3B_HUMAN	Submaxillary gland androgen-regulated protein 3B	7982889	Molecular cloning and sequence analysis of cDNA coding for the precursor of the human salivary proline-rich peptide P-B.

Q9Y458	TBX22_HUMAN	T-box transcription factor TBX22	11024289	Molecular characterization of a new human T-box gene (TBX22) located in Xq21.1 encoding a protein containing a truncated T-domain.

P32495	NHP2_YEAST	H/ACA ribonucleoprotein complex subunit 2	11433018	Accumulation of H/ACA snoRNPs depends on the integrity of the conserved central domain of the RNA-binding protein Nhp2p.

Q12815	TROAP_HUMAN	Tastin	7758945	Trophinin and tastin, a novel cell adhesion molecule complex with potential involvement in embryo implantation.

Q02202	ECM9_YEAST	Protein ECM9	9335584	Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae.

P01595	KV103_HUMAN	Ig kappa chain V-I region Bi	4563064	Principle of antibody structure. The primary structure of a monoclonal kappa I-type immunoglobulin L-chain (Bence Jones protein Bi). 3. The complete amino acid sequence and the genetic significance of the variability principles for the mechanism of antibody formation.

P63242	IF5A1_MOUSE	Eukaryotic translation initiation factor 5A-1	17707773	The N-terminal region of eukaryotic translation initiation factor 5A signals to nuclear localization of the protein.

P84272	DAH56_LITDA	Dahlein-5.6	11555873	Bioactive dahlein peptides from the skin secretions of the Australian aquatic frog Litoria dahlii: sequence determination by electrospray mass spectrometry.

Q63073	BTG1_RAT	Protein BTG1	7588335	Stage-specific expression of B cell translocation gene 1 in rat testis.

P40454	PTPA1_YEAST	Serine/threonine-protein phosphatase 2A activator 1	11134337	The phosphotyrosyl phosphatase activator, Ncs1p (Rrd1p), functions with Cla4p to regulate the G(2)/M transition in Saccharomyces cerevisiae.

Q9I7S8	PUR6_DROME	Multifunctional protein ADE2	10757766	The Drosophila melanogaster ade5 gene encodes a bifunctional enzyme for two steps in the de novo purine synthesis pathway.

Q9BV73	CP250_HUMAN	Centrosome-associated protein CEP250	10880350	NIMA-related kinase 2 (Nek2), a cell-cycle-regulated protein kinase localized to centrosomes, is complexed to protein phosphatase 1.

Q9V730	EXT1_DROME	Exostosin-1	10549295	Hedgehog movement is regulated through tout velu-dependent synthesis of a heparan sulfate proteoglycan.

Q868T3	CCAPR_DROME	Cardioacceleratory peptide receptor	12646179	Molecular identification of a Drosophila G protein-coupled receptor specific for crustacean cardioactive peptide.

O00206	TLR4_HUMAN	Toll-like receptor 4	10835634	TLR4 mutations are associated with endotoxin hyporesponsiveness in humans.

Q90240	CBPD_ANAPL	Carboxypeptidase D	8138993	A cell surface protein that binds avian hepatitis B virus particles.

O43236	SEPT4_HUMAN	Septin-4	11146656	A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif.

P07742	RIR1_MOUSE	Ribonucleoside-diphosphate reductase large subunit	19176520	Molecular mechanisms of thioredoxin and glutaredoxin as hydrogen donors for mammalian S phase ribonucleotide reductase.

Q9SAA2	CLPP6_ARATH	ATP-dependent Clp protease proteolytic subunit 6, chloroplastic	14593120	Clp protease complexes from photosynthetic and non-photosynthetic plastids and mitochondria of plants, their predicted three-dimensional structures, and functional implications.

Q9HDZ5	YKP9_SCHPO	CRAL-TRIO domain-containing protein C589.09, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q05652	KPEL_DROME	Serine/threonine-protein kinase pelle	10589682	Three-dimensional structure of a complex between the death domains of Pelle and Tube.

P27816	MAP4_HUMAN	Microtubule-associated protein 4	1905296	Non-neuronal 210 x 10(3) Mr microtubule-associated protein (MAP4) contains a domain homologous to the microtubule-binding domains of neuronal MAP2 and tau.

Q90Z00	FGR1A_DANRE	Basic fibroblast growth factor receptor 1-A	15221377	Zebrafish fgfr1 is a member of the fgf8 synexpression group and is required for fgf8 signalling at the midbrain-hindbrain boundary.

O14139	HRP3_SCHPO	Chromodomain helicase hrp3	12127990	Hrp3, a chromodomain helicase/ATPase DNA binding protein, is required for heterochromatin silencing in fission yeast.

P30189	TOP1_DROME	DNA topoisomerase 1	14871887	Drosophila Topors is a RING finger-containing protein that functions as a ubiquitin-protein isopeptide ligase for the hairy basic helix- loop-helix repressor protein.

P82172	DLP1_ORNAN	Defensin-like peptide 1	10417345	Solution structure of a defensin-like peptide from platypus venom.

P47144	ECM27_YEAST	Protein ECM27	9335584	Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae.

Q9ZT91	EFTM_ARATH	Elongation factor Tu, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

O88627	S28A2_MOUSE	Sodium/nucleoside cotransporter 2	10721696	Cloning, genomic organization and chromosomal localization of the gene encoding the murine sodium-dependent, purine-selective, concentrative nucleoside transporter (CNT2).

P21266	GSTM3_HUMAN	Glutathione S-transferase Mu 3	2345169	A distinct human testis and brain mu-class glutathione S-transferase. Molecular cloning and characterization of a form present even in individuals lacking hepatic type mu isoenzymes.

Q99502	EYA1_HUMAN	Eyes absent homolog 1	19234442	Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions.

P34164	SIP2_YEAST	SNF1 protein kinase subunit beta-2	11331606	Subcellular localization of the Snf1 kinase is regulated by specific beta subunits and a novel glucose signaling mechanism.

Q86I44	LIMF_DICDI	LIM domain-containing protein F	15962002	A Rab21/LIM-only/CH-LIM complex regulates phagocytosis via both activating and inhibitory mechanisms.

Q96CG3	TIFA_HUMAN	TRAF-interacting protein with FHA domain-containing protein A	16643855	A novel Zinc finger protein, ZCCHC11, interacts with TIFA and modulates TLR signaling.

Q13972	RGRF1_HUMAN	Ras-specific guanine nucleotide-releasing factor 1	7684828	Identification of a human guanine nucleotide-releasing factor (H- GRF55) specific for Ras proteins.

Q9LFG2	DAPF_ARATH	Diaminopimelate epimerase, chloroplastic	15652176	Biosynthesis of lysine in plants: evidence for a variant of the known bacterial pathways.

O94777	DPM2_HUMAN	Dolichol phosphate-mannose biosynthesis regulatory protein	10835346	Human dolichol-phosphate-mannose synthase consists of three subunits, DPM1, DPM2 and DPM3.

P01833	PIGR_HUMAN	Polymeric immunoglobulin receptor	2920039	Molecular cloning of the human transmembrane secretory component (poly-Ig receptor) and its mRNA expression in human tissues.

B6ZI38	DRAXI_CHICK	Draxin	19150847	Draxin, a repulsive guidance protein for spinal cord and forebrain commissures.

Q96LA8	ANM6_HUMAN	Protein arginine N-methyltransferase 6	16600869	Arginine methylation regulates DNA polymerase beta.

Q60520	SIN3A_MOUSE	Paired amphipathic helix protein Sin3a	7889570	Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3.

P36532	RM37_YEAST	54S ribosomal protein L37, mitochondrial	2060626	Extended N-terminal sequencing of proteins of the large ribosomal subunit from yeast mitochondria.

Q05521	DPP1_YEAST	Diacylglycerol pyrophosphate phosphatase 1	10545184	Mutagenesis of the phosphatase sequence motif in diacylglycerol pyrophosphate phosphatase from Saccharomyces cerevisiae.

P77375	YDHX_ECOLI	Uncharacterized ferredoxin-like protein ydhX	17218314	Export pathway selectivity of Escherichia coli twin arginine translocation signal peptides.

Q96J02	ITCH_HUMAN	E3 ubiquitin-protein ligase Itchy homolog	17028573	Itch/AIP4 mediates Deltex degradation through the formation of K29- linked polyubiquitin chains.

P00533	EGFR_HUMAN	Epidermal growth factor receptor	7657591	Tyrosine phosphorylation of the c-cbl proto-oncogene protein product and association with epidermal growth factor (EGF) receptor upon EGF stimulation.

P54318	LIPR2_RAT	Pancreatic lipase-related protein 2	8486693	Identification and cloning of GP-3 from rat pancreatic acinar zymogen granules as a glycosylated membrane-associated lipase.

P87231	MUS81_SCHPO	Crossover junction endonuclease mus81	14704204	Fission yeast Mus81.Eme1 Holliday junction resolvase is required for meiotic crossing over but not for gene conversion.

Q99J82	ILK_RAT	Integrin-linked protein kinase	11304546	Integrin-linked kinase (ILK) binding to paxillin LD1 motif regulates ILK localization to focal adhesions.

P39748	FEN1_HUMAN	Flap endonuclease 1	11430825	Regulation of human flap endonuclease-1 activity by acetylation through the transcriptional coactivator p300.

P03989	1B27_HUMAN	HLA class I histocompatibility antigen, B-27 alpha chain	3011411	Gene conversion-like mechanisms may generate polymorphism in human class I genes.

Q8TET4	GANC_HUMAN	Neutral alpha-glucosidase C	12370436	Computer assisted cloning of human neutral alpha glucosidase C (GANC): a new paralog in the glycosyl hydrolase gene family 31.

Q8W2F3	PIF4_ARATH	Transcription factor PIF4	12897250	The Arabidopsis basic/helix-loop-helix transcription factor family.

Q96S37	S22AC_HUMAN	Solute carrier family 22 member 12	15304510	The multivalent PDZ domain-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus.

Q9CXF4	TBC15_MOUSE	TBC1 domain family member 15	16055087	TBC domain family, member 15 is a novel mammalian Rab GTPase- activating protein with substrate preference for Rab7.

Q12355	PST1_YEAST	Cell wall mannoprotein PST1	10234784	Two-dimensional analysis of proteins secreted by Saccharomyces cerevisiae regenerating protoplasts: a novel approach to study the cell wall.

O59710	ADRO_SCHPO	Probable NADPH:adrenodoxin oxidoreductase, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8N6C5	IGSF1_HUMAN	Immunoglobulin superfamily member 1	11266516	Modulation of activin signal transduction by inhibin B and inhibin- binding protein (INhBP).

P40386	THI4_SCHPO	Probable thiamine biosynthetic bifunctional enzyme	7961415	Cloning, nucleotide sequence, and regulation of Schizosaccharomyces pombe thi4, a thiamine biosynthetic gene.

Q9UBF9	MYOTI_HUMAN	Myotilin	10369880	Myotilin, a novel sarcomeric protein with two Ig-like domains, is encoded by a candidate gene for limb-girdle muscular dystrophy.

Q01954	BNC1_HUMAN	Zinc finger protein basonuclin-1	9099851	The human basonuclin gene.

O60138	YNS7_SCHPO	Uncharacterized protein C18H10.07	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P13864	DNMT1_MOUSE	DNA (cytosine-5)-methyltransferase 1	10615135	DNA methyltransferase Dnmt1 associates with histone deacetylase activity.

P78968	PPZ_SCHPO	Serine/threonine-protein phosphatase PP-Z	9428701	Regulation of salt tolerance in fission yeast by a protein- phosphatase-Z-like Ser/Thr protein phosphatase.

P42841	PFS2_YEAST	Polyadenylation factor subunit 2	10619842	The WD-repeat protein pfs2p bridges two essential factors within the yeast pre-mRNA 3'-end-processing complex.

P14672	GTR4_HUMAN	Solute carrier family 2, facilitated glucose transporter member 4	11842083	The insulin-sensitive glucose transporter, GLUT4, interacts physically with Daxx. Two proteins with capacity to bind Ubc9 and conjugated to SUMO1.

P34160	NCBP1_YEAST	Nuclear cap-binding protein complex subunit 1	15753296	Cap-binding protein 1-mediated and eukaryotic translation initiation factor 4E-mediated pioneer rounds of translation in yeast.

Q9VW15	ASH1_DROME	Histone-lysine N-methyltransferase ash1	7982557	Molecular genetic analysis of the Drosophila melanogaster gene absent, small or homeotic discs1 (ash1).

Q96GM5	SMRD1_HUMAN	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1	8804307	Diversity and specialization of mammalian SWI/SNF complexes.

P15429	ENOB_RAT	Beta-enolase	8594891	Differential expression of alpha- and beta-enolase genes during rat heart development and hypertrophy.

Q96PQ0	SORC2_HUMAN	VPS10 domain-containing receptor SorCS2	11499680	The genes for the human VPS10 domain-containing receptors are large and contain many small exons.

Q9JHH6	CBPB2_MOUSE	Carboxypeptidase B2	10739389	Characterization of mouse thrombin-activatable fibrinolysis inhibitor.

Q14686	NCOA6_HUMAN	Nuclear receptor coactivator 6	10567404	A nuclear factor ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo.

O95396	MOCS3_HUMAN	Adenylyltransferase and sulfurtransferase MOCS3	18650437	A novel role for human Nfs1 in the cytoplasm: Nfs1 acts as a sulfur donor for MOCS3, a protein involved in molybdenum cofactor biosynthesis.

P24100	CDKA1_ARATH	Cyclin-dependent kinase A-1	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

P03958	ADA_MOUSE	Adenosine deaminase	2387582	Structural and functional analysis of the murine adenosine deaminase gene.

Q9UP52	TFR2_HUMAN	Transferrin receptor protein 2	10409623	Molecular cloning of transferrin receptor 2: a new member of the transferrin receptor-like family.

Q9UVI4	THYD_CLAFS	Trihydrophobin	10336622	Identification and characterization of a tri-partite hydrophobin from Claviceps fusiformis: a novel type of class II hydrophobin.

Q12967	GNDS_HUMAN	Ral guanine nucleotide dissociation stimulator	7972015	Activated Ras interacts with the Ral guanine nucleotide dissociation stimulator.

P87051	PPIL1_SCHPO	Peptidyl-prolyl cis-trans isomerase ppi1	11690648	Cyclophilins of a novel subfamily interact with SNW/SKIP coregulator in Dictyostelium discoideum and Schizosaccharomyces pombe.

Q9FYA6	BCAT5_ARATH	Branched-chain-amino-acid aminotransferase 5, chloroplastic	12068099	The branched-chain amino acid transaminase gene family in Arabidopsis encodes plastid and mitochondrial proteins.

Q9XTC6	MOM4_CAEEL	Mitogen-activated protein kinase kinase kinase mom-4	10391246	MAP kinase and Wnt pathways converge to downregulate an HMG-domain repressor in Caenorhabditis elegans.

O42649	SMC3_SCHPO	Structural maintenance of chromosomes protein 3	11069892	Characterization of fission yeast cohesin: essential anaphase proteolysis of Rad21 phosphorylated in the S phase.

O15372	EIF3H_HUMAN	Eukaryotic translation initiation factor 3 subunit H	9341143	Structure of cDNAs encoding human eukaryotic initiation factor 3 subunits. Possible roles in RNA binding and macromolecular assembly.

P01893	HLAH_HUMAN	Putative HLA class I histocompatibility antigen, alpha chain H	6461010	Exon/intron organization and complete nucleotide sequence of an HLA gene.

Q8K0S0	PHYIP_MOUSE	Phytanoyl-CoA hydroxylase-interacting protein	10686344	Identification of a brain specific protein that associates with a Refsum disease gene product, phytanoyl-CoA alpha-hydroxylase.

P46422	GSTF4_ARATH	Glutathione S-transferase PM24	8290582	Photoaffinity labeling of Arabidopsis thaliana plasma membrane vesicles by 5-azido-[7-3H]indole-3-acetic acid: identification of a glutathione S-transferase.

O08557	DDAH1_RAT	N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	9003431	Cloning and sequencing of cDNA encoding NG,NG-dimethylarginine dimethylaminohydrolase from rat kidney.

Q42546	DPNP1_ARATH	SAL1 phosphatase	17993620	Arabidopsis FIERY1, XRN2, and XRN3 are endogenous RNA silencing suppressors.

Q9NH13	RP43_RIFPA	Exoskeleton protein RP43	10947956	Characterization of a cDNA encoding RP43, a CUB-domain-containing protein from the tube of Riftia pachyptila (Vestimentifera), and distribution of its transcript.

Q8BUV6	LSM11_MOUSE	U7 snRNA-associated Sm-like protein LSm11	12975319	Unique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processing.

P50748	KNTC1_HUMAN	Kinetochore-associated protein 1	12686595	Zwilch, a new component of the ZW10/ROD complex required for kinetochore functions.

P25359	RRP43_YEAST	Exosome complex component RRP43	10465791	The yeast exosome and human PM-Scl are related complexes of 3'-->5' exonucleases.

Q9UDY8	MALT1_HUMAN	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	15125833	The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes.

Q86L14	PUR9_DICDI	Bifunctional purine biosynthesis protein purH	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q17850	PAK1_CAEEL	Serine/threonine-protein kinase pak-1	9535804	Expression pattern of the C. elegans p21-activated protein kinase, CePAK.

P25071	CML12_ARATH	Calmodulin-like protein 12	8564305	Touch-inducible genes for calmodulin and a calmodulin-related protein are located in tandem on a chromosome of Arabidopsis thaliana.

P92208	JNK_DROME	Stress-activated protein kinase JNK	11784101	JNK signaling pathway is required for efficient wound healing in Drosophila.

P15454	KGUA_YEAST	Guanylate kinase	1334480	Cloning and expression of the essential gene for guanylate kinase from yeast.

Q9R0K7	AT2B2_MOUSE	Plasma membrane calcium-transporting ATPase 2	11985881	A mouse with a point mutation in plasma membrane Ca2+-ATPase isoform 2 gene showed the reduced Ca2+ influx in cerebellar neurons.

Q9Y6Q9	NCOA3_HUMAN	Nuclear receptor coactivator 3	9267036	Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300.

Q63276	BAAT_RAT	Bile acid-CoA:amino acid N-acyltransferase	7575455	Reduced expression of kan-1 (encoding putative bile acid-CoA-amino acid N-acyltransferase) mRNA in livers of rats after partial hepatectomy and during sepsis.

O14129	RAD55_SCHPO	DNA repair protein rhp55	10430583	A new recombinational DNA repair gene from Schizosaccharomyces pombe with homology to Escherichia coli RecA.

P41970	ELK3_HUMAN	ETS domain-containing protein Elk-3	7958835	Net, a new ets transcription factor that is activated by Ras.

Q07527	TRM3_YEAST	tRNA guanosine-2'-O-methyltransferase TRM3	9917067	The yeast Saccharomyces cerevisiae YDL112w ORF encodes the putative 2'-O-ribose methyltransferase catalyzing the formation of Gm18 in tRNAs.

Q8R2H5	PHLD_RAT	Phosphatidylinositol-glycan-specific phospholipase D	11855934	Insulin reduces serum glycosylphosphatidylinositol phospholipase D levels in human type I diabetic patients and streptozotocin diabetic rats.

Q3KPK4	BORE1_XENLA	Borealin	15260989	The chromosomal passenger complex is required for chromatin-induced microtubule stabilization and spindle assembly.

P13009	METH_ECOLI	Methionine synthase	2668277	Cloning and sequence analysis of the Escherichia coli metH gene encoding cobalamin-dependent methionine synthase and isolation of a tryptic fragment containing the cobalamin-binding domain.

Q5B430	BTGC_EMENI	Glucan endo-1,3-beta-glucosidase btgC	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

Q01658	NC2B_HUMAN	Protein Dr1	8670811	A mechanism for repression of class II gene transcription through specific binding of NC2 to TBP-promoter complexes via heterodimeric histone fold domains.

Q9LVN2	Y5815_ARATH	Probably inactive leucine-rich repeat receptor-like protein kinase At5g58150	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P32598	PP12_YEAST	Serine/threonine-protein phosphatase PP1-2	12819204	Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-ends.

Q09161	NCBP1_HUMAN	Nuclear cap-binding protein subunit 1	12434151	Structural basis of m7GpppG binding to the nuclear cap-binding protein complex.

Q9FE38	POT3_ARATH	Potassium transporter 3	11158535	TRH1 encodes a potassium transporter required for tip growth in Arabidopsis root hairs.

P54678	ATC1_DICDI	Calcium-transporting ATPase PAT1	7499325	Molecular cloning of an intracellular P-type ATPase from Dictyostelium that is up-regulated in calcium-adapted cells.

Q9GZV3	SC5A7_HUMAN	High affinity choline transporter 1	11068039	Functional characterization of the human high-affinity choline transporter.

Q42029	PSBP1_ARATH	Oxygen-evolving enhancer protein 2-1, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q39008	M3K1_ARATH	Mitogen-activated protein kinase kinase kinase 1	10556579	Functional characterization of ARAKIN (ATMEKK1): a possible mediator in an osmotic stress response pathway in higher plants.

O60921	HUS1_HUMAN	Checkpoint protein HUS1	10359610	The human G2 checkpoint control protein hRAD9 is a nuclear phosphoprotein that forms complexes with hRAD1 and hHUS1.

P03485	M1_I34A1	Matrix protein 1	11531417	Effect of influenza virus matrix protein and viral RNA on ribonucleoprotein formation and nuclear export.

Q924V1	NOX4_RAT	NADPH oxidase 4	15322091	Direct interaction of the novel Nox proteins with p22phox is required for the formation of a functionally active NADPH oxidase.

P29348	GNAT3_RAT	Guanine nucleotide-binding protein G(t) subunit alpha-3	7626029	Functional expression of the taste specific G-protein, alpha- gustducin.

Q966Q9	CBPH_DICDI	Calcium-binding protein H	14706075	Identification and characterization of novel calcium-binding proteins of Dictyostelium and their spatial expression patterns during development.

Q8N8Q8	COX18_HUMAN	Mitochondrial inner membrane protein COX18	16911509	The COX18 gene, involved in mitochondrial biogenesis, is functionally conserved and tightly regulated in humans and fission yeast.

P40507	AIR1_YEAST	Protein AIR1	15828860	A new yeast poly(A) polymerase complex involved in RNA quality control.

Q84UV0	LINS_ARATH	Linalool synthase, chloroplastic	12566586	Biosynthesis and emission of terpenoid volatiles from Arabidopsis flowers.

P62495	ERF1_HUMAN	Eukaryotic peptide chain release factor subunit 1	7990965	A highly conserved eukaryotic protein family possessing properties of polypeptide chain release factor.

Q9VBW6	DAN_DROME	Protein distal antenna	17493605	distal antenna and distal antenna-related function in the retinal determination network during eye development in Drosophila.

Q18221	SET2_CAEEL	Probable histone-lysine N-methyltransferase set-2	11729150	Depletion of a novel SET-domain protein enhances the sterility of mes-3 and mes-4 mutants of Caenorhabditis elegans.

P39306	ULAF_ECOLI	L-ribulose-5-phosphate 4-epimerase ulaF	11741871	Utilization of L-ascorbate by Escherichia coli K-12: assignments of functions to products of the yjf-sga and yia-sgb operons.

P28325	CYTD_HUMAN	Cystatin-D	8083219	Structural and functional characterization of two allelic variants of human cystatin D sharing a characteristic inhibition spectrum against mammalian cysteine proteinases.

P40079	LCP5_YEAST	U3 small nucleolar ribonucleoprotein protein LCP5	9814757	Synthetic lethal interactions with conditional poly(A) polymerase alleles identify LCP5, a gene involved in 18S rRNA maturation.

Q90VV1	HES4B_XENLA	Transcription factor HES-4-B	16586347	Two modes of action by which Xenopus hairy2b establishes tissue demarcation in the Spemann-Mangold organizer.

Q8C6P8	ZFP57_MOUSE	Zinc finger protein 57	15070898	Identification and characterization of ZFP-57, a novel zinc finger transcription factor in the mammalian peripheral nervous system.

P25765	CHI12_ORYSJ	Chitinase 12	12885168	Co-expression of a modified maize ribosome-inactivating protein and a rice basic chitinase gene in transgenic rice plants confers enhanced resistance to sheath blight.

P38629	RFC3_YEAST	Replication factor C subunit 3	12604797	Yeast Rad17/Mec3/Ddc1: a sliding clamp for the DNA damage checkpoint.

P36551	HEM6_HUMAN	Coproporphyrinogen-III oxidase, mitochondrial	9888388	Systematic analysis of coproporphyrinogen oxidase gene defects in hereditary coproporphyria and mutation update.

Q9UHI8	ATS1_HUMAN	A disintegrin and metalloproteinase with thrombospondin motifs 1	10438512	METH-1, a human ortholog of ADAMTS-1, and METH-2 are members of a new family of proteins with angio-inhibitory activity.

O75691	UTP20_HUMAN	Small subunit processome component 20 homolog	9673349	Differential gene expression in mammary carcinoma cell lines: identification of DRIM, a new gene down-regulated in metastasis.

P32578	SIP1_YEAST	SNF1 protein kinase subunit beta-1	1496382	A protein kinase substrate identified by the two-hybrid system.

Q12705	PP2B_SCHPO	Serine/threonine-protein phosphatase 2B catalytic subunit	7983142	A calcineurin-like gene ppb1+ in fission yeast: mutant defects in cytokinesis, cell polarity, mating and spindle pole body positioning.

P41812	POP1_YEAST	Ribonucleases P/MRP protein subunit POP1	7926742	The POP1 gene encodes a protein component common to the RNase MRP and RNase P ribonucleoproteins.

P37047	CDAR_ECOLI	Carbohydrate diacid regulator	10762278	A common regulator for the operons encoding the enzymes involved in D-galactarate, D-glucarate, and D-glycerate utilization in Escherichia coli.

Q92358	BQT1_SCHPO	Telomere bouquet protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O42904	PRP31_SCHPO	Pre-mRNA-processing factor 31	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P13385	TDGF1_HUMAN	Teratocarcinoma-derived growth factor 1	12919325	The CRIPTO/FRL-1/CRYPTIC (CFC) domain of human Cripto.

Q924W9	RBTN1_MOUSE	Rhombotin-1	1703797	T-cell translocation gene 1 (Ttg-1) encodes a nuclear protein normally expressed in neural lineage cells.

O35129	PHB2_MOUSE	Prohibitin-2	15140878	Transcriptional regulation by the repressor of estrogen receptor activity via recruitment of histone deacetylases.

P46944	TRS85_YEAST	Transport protein particle 85 kDa subunit	10727015	Identification and characterization of five new subunits of TRAPP.

Q7L804	RFIP2_HUMAN	Rab11 family-interacting protein 2	16905101	Crystal structure of rab11 in complex with rab11 family interacting protein 2.

P32873	BEM3_YEAST	GTPase-activating protein BEM3	8227021	Biochemical comparisons of the Saccharomyces cerevisiae Bem2 and Bem3 proteins. Delineation of a limit Cdc42 GTPase-activating protein domain.

Q9V4Z9	LINES_DROME	Protein lines	8620835	The roles of hedgehog, wingless and lines in patterning the dorsal epidermis in Drosophila.

P38778	SMF2_YEAST	Manganese transporter SMF2	11027260	Saccharomyces cerevisiae expresses three functionally distinct homologues of the nramp family of metal transporters.

Q80VW5	WHRN_MOUSE	Whirlin	12833159	Defects in whirlin, a PDZ domain molecule involved in stereocilia elongation, cause deafness in the whirler mouse and families with DFNB31.

P49704	PRP31_YEAST	Pre-mRNA-processing factor 31	9199293	Prp31p promotes the association of the U4/U6.U5 tri-snRNP with prespliceosomes to form spliceosomes in Saccharomyces cerevisiae.

P19524	MYO2_YEAST	Myosin-2	11381095	The yeast class V myosins, Myo2p and Myo4p, are nonprocessive actin- based motors.

Q10180	MU113_SCHPO	Meiotically up-regulated gene 113 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q05899	YL297_YEAST	Uncharacterized vacuolar protein YLR297W	14562095	Global analysis of protein localization in budding yeast.

Q99747	SNAG_HUMAN	Gamma-soluble NSF attachment protein	11278501	Gaf-1, a gamma-SNAP-binding protein associated with the mitochondria.

Q9UP95	S12A4_HUMAN	Solute carrier family 12 member 4	8663127	Molecular cloning and functional expression of the K-Cl cotransporter from rabbit, rat, and human. A new member of the cation-chloride cotransporter family.

P24280	SEC14_YEAST	SEC14 cytosolic factor	2215682	An essential role for a phospholipid transfer protein in yeast Golgi function.

Q6NZI2	PTRF_HUMAN	Polymerase I and transcript release factor	15242332	Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes.

O15533	TPSN_HUMAN	Tapasin	9271576	A critical role for tapasin in the assembly and function of multimeric MHC class I-TAP complexes.

A2APB8	TPX2_MOUSE	Targeting protein for Xklp2	18663142	Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A.

P02833	ANTP_DROME	Homeotic protein antennapedia	3821869	Redesigning the body plan of Drosophila by ectopic expression of the homoeotic gene Antennapedia.

Q8TD08	MK15_HUMAN	Mitogen-activated protein kinase 15	11875070	ERK8, a new member of the mitogen-activated protein kinase family.

Q8C0J2	A16L1_MOUSE	Autophagy-related protein 16-1	12665549	Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate.

Q17TI5	BRX_ARATH	Protein BREVIS RADIX	15031265	Natural genetic variation in Arabidopsis identifies BREVIS RADIX, a novel regulator of cell proliferation and elongation in the root.

Q06406	LSM6_YEAST	U6 snRNA-associated Sm-like protein LSm6	10369684	Sm and Sm-like proteins assemble in two related complexes of deep evolutionary origin.

P59046	NAL12_HUMAN	NACHT, LRR and PYD domains-containing protein 12	12019269	PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing.

Q06623	HDA3_YEAST	HDA1 complex subunit 3	14562095	Global analysis of protein localization in budding yeast.

Q9FKK2	AGL62_ARATH	Agamous-like MADS-box protein AGL62	18334668	The AGL62 MADS domain protein regulates cellularization during endosperm development in Arabidopsis.

Q01649	CIK1_YEAST	Spindle pole body-associated protein CIK1	1644287	CIK1: a developmentally regulated spindle pole body-associated protein important for microtubule functions in Saccharomyces cerevisiae.

Q9ZV53	ATL49_ARATH	Putative RING-H2 finger protein ATL49	15634699	Genetic and molecular identification of genes required for female gametophyte development and function in Arabidopsis.

P48744	NDP_MOUSE	Norrin	15035989	Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair.

Q10452	GSK3_SCHPO	Protein kinase gsk3	12773390	The role of Ppe1/PP6 phosphatase for equal chromosome segregation in fission yeast kinetochore.

Q9SSM7	PYL3_ARATH	Abscisic acid receptor PYL3	19898420	A gate-latch-lock mechanism for hormone signalling by abscisic acid receptors.

Q91V27	MELPH_MOUSE	Melanophilin	11887186	Identification of an organelle receptor for myosin-Va.

P15258	RAL2_SCHPO	Protein ral2	2586528	Characterization of the Schizosaccharomyces pombe ral2 gene implicated in activation of the ras1 gene product.

P34326	HM16_CAEEL	Homeobox protein engrailed-like ceh-16	15659483	ceh-16/engrailed patterns the embryonic epidermis of Caenorhabditis elegans.

Q02792	XRN2_YEAST	5'-3' exoribonuclease 2	9315672	Rat1p and Xrn1p are functionally interchangeable exoribonucleases that are restricted to and required in the nucleus and cytoplasm, respectively.

P09758	TACD2_HUMAN	Tumor-associated calcium signal transducer 2	7665234	Cloning of the gene encoding Trop-2, a cell-surface glycoprotein expressed by human carcinomas.

Q969F2	NKD2_HUMAN	Protein naked cuticle homolog 2	18757723	EGF receptor-independent action of TGF-alpha protects Naked2 from AO7-mediated ubiquitylation and proteasomal degradation.

Q10666	POP1_CAEEL	Protein pop-1	11742996	A POP-1 repressor complex restricts inappropriate cell type-specific gene transcription during Caenorhabditis elegans embryogenesis.

P05181	CP2E1_HUMAN	Cytochrome P450 2E1	3233219	Human ethanol-inducible P450IIE1: complete gene sequence, promoter characterization, chromosome mapping, and cDNA-directed expression.

O70461	MOT3_RAT	Monocarboxylate transporter 3	9841555	Monocarboxylate transporter MCT1 is located in the apical membrane and MCT3 in the basal membrane of rat RPE.

P00973	OAS1_HUMAN	2'-5'-oligoadenylate synthase 1	3754863	Structure and expression of a cloned cDNA for human (2'- 5')oligoadenylate synthetase.

P40858	RN49_YEAST	54S ribosomal protein L49, mitochondrial	12392552	Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components.

Q08687	TMA16_YEAST	Translation machinery-associated protein 16	14562095	Global analysis of protein localization in budding yeast.

Q9VF30	MCMR_DROME	DNA replication licensing factor REC	14676427	REC, a new member of the MCM-related protein family, is required for meiotic recombination in Drosophila.

P08018	PBS2_YEAST	MAP kinase kinase PBS2	7624781	Activation of yeast PBS2 MAPKK by MAPKKKs or by binding of an SH3- containing osmosensor.

P82911	RT11_BOVIN	28S ribosomal protein S11, mitochondrial	11279123	The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present.

Q9W6A7	OPSR1_DANRE	Red-sensitive opsin-1	10349976	Cloning and characterization of six zebrafish photoreceptor opsin cDNAs and immunolocalization of their corresponding proteins.

P92973	CCA1_ARATH	Protein CCA1	9657153	Constitutive expression of the CIRCADIAN CLOCK ASSOCIATED 1 (CCA1) gene disrupts circadian rhythms and suppresses its own expression.

Q9EQ61	PESC_MOUSE	Pescadillo homolog	12237316	Pescadillo is essential for nucleolar assembly, ribosome biogenesis, and mammalian cell proliferation.

P10916	MLRV_HUMAN	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform	8287067	Interaction of a conserved peptide domain in recombinant human ventricular myosin light chain-2 with myosin heavy chain.

P31387	5HT5B_MOUSE	5-hydroxytryptamine receptor 5B	8450829	Mouse 5-hydroxytryptamine5A and 5-hydroxytryptamine5B receptors define a new family of serotonin receptors: cloning, functional expression, and chromosomal localization.

Q12884	SEPR_HUMAN	Seprase	9065413	Identification of the 170-kDa melanoma membrane-bound gelatinase (seprase) as a serine integral membrane protease.

P63094	GNAS2_MOUSE	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	3092218	Inhibitory and stimulatory G proteins of adenylate cyclase: cDNA and amino acid sequences of the alpha chains.

Q9R0M8	S35A2_MOUSE	UDP-galactose translocator	10578063	Indispensability of transmembrane domains of Golgi UDP-galactose transporter as revealed by analysis of genetic defects in UDP- galactose transporter-deficient murine had-1 mutant cell lines and construction of deletion mutants.

O55176	PJA1_MOUSE	E3 ubiquitin-protein ligase Praja-1	11959851	A RING finger protein Praja1 regulates Dlx5-dependent transcription through its ubiquitin ligase activity for the Dlx/Msx-interacting MAGE/Necdin family protein, Dlxin-1.

P51689	ARSD_HUMAN	Arylsulfatase D	7720070	A cluster of sulfatase genes on Xp22.3: mutations in chondrodysplasia punctata (CDPX) and implications for warfarin embryopathy.

Q12196	RIO1_YEAST	Serine/threonine-protein kinase RIO1	11483523	Processing of 20S pre-rRNA to 18S ribosomal RNA in yeast requires Rrp10p, an essential non-ribosomal cytoplasmic protein.

Q9Y6N8	CAD10_HUMAN	Cadherin-10	10861224	Identification of three human type-II classic cadherins and frequent heterophilic interactions between different subclasses of type-II classic cadherins.

Q9LXC9	IPYR1_ARATH	Soluble inorganic pyrophosphatase 1, chloroplastic	15135060	Identification of an Arabidopsis inorganic pyrophosphatase capable of being imported into chloroplasts.

Q99496	RING2_HUMAN	E3 ubiquitin-protein ligase RING2	15960975	Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

P15725	TNR4_RAT	Tumor necrosis factor receptor superfamily member 4	2157591	Characterization of the MRC OX40 antigen of activated CD4 positive T lymphocytes -- a molecule related to nerve growth factor receptor.

Q91VE0	S27A4_MOUSE	Long-chain fatty acid transport protein 4	11404000	Mouse fatty acid transport protein 4 (FATP4): characterization of the gene and functional assessment as a very long chain acyl-CoA synthetase.

O95197	RTN3_HUMAN	Reticulon-3	10331947	Cloning of a novel member of the reticulon gene family (RTN3): gene structure and chromosomal localization to 11q13.

Q9UER7	DAXX_HUMAN	Death domain-associated protein 6	11842083	The insulin-sensitive glucose transporter, GLUT4, interacts physically with Daxx. Two proteins with capacity to bind Ubc9 and conjugated to SUMO1.

P55072	TERA_HUMAN	Transitional endoplasmic reticulum ATPase	19818707	The otubain YOD1 is a deubiquitinating enzyme that associates with p97 to facilitate protein dislocation from the ER.

Q10177	PDT1_SCHPO	Manganese transporter pdt1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P36105	RL14A_YEAST	60S ribosomal protein L14-A	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

O75011	NAK1_SCHPO	Serine/threonine-protein kinase nak1	12427731	Nak1, an essential GC kinase regulates cell morphology and growth in Schizosaccharomyces pombe.

O74547	BIT61_SCHPO	Target of rapamycin complex 2 subunit bit61	18076573	Rapamycin sensitivity of the Schizosaccharomyces pombe tor2 mutant and organization of two highly phosphorylated TOR complexes by specific and common subunits.

P32662	GPH_ECOLI	Phosphoglycolate phosphatase	13129953	Role of 2-phosphoglycolate phosphatase of Escherichia coli in metabolism of the 2-phosphoglycolate formed in DNA repair.

P43637	TOS3_YEAST	Serine/threonine-protein kinase TOS3	15340085	Pak1 protein kinase regulates activation and nuclear localization of Snf1-Gal83 protein kinase.

Q96301	SPY_ARATH	Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY	15155885	SPINDLY and GIGANTEA interact and act in Arabidopsis thaliana pathways involved in light responses, flowering, and rhythms in cotyledon movements.

P14220	GLPA_MOUSE	Glycophorin-A	12940824	Glycophorin A requirement for expression of O-linked antigens on the erythrocyte membrane.

Q8K4H1	AFMID_MOUSE	Probable arylformamidase	15866519	Effect of arylformamidase (kynurenine formamidase) gene inactivation in mice on enzymatic activity, kynurenine pathway metabolites and phenotype.

Q80WG7	TRI36_MOUSE	E3 ubiquitin-protein ligase Trim36	12917430	Haprin, a novel haploid germ cell-specific RING finger protein involved in the acrosome reaction.

Q12381	PRP1_SCHPO	Pre-mRNA-splicing factor prp1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NP55	PLUNC_HUMAN	Protein Plunc	11425234	Identification of a new potential airway irritation marker, palate lung nasal epithelial clone protein, in human nasal lavage fluid with two-dimensional electrophoresis and matrix-assisted laser desorption/ionization-time of flight.

P15207	ANDR_RAT	Androgen receptor	12350225	A novel steroid receptor co-activator protein (SRAP) as an alternative form of steroid receptor RNA-activator gene: expression in prostate cancer cells and enhancement of androgen receptor activity.

Q5VT25	MRCKA_HUMAN	Serine/threonine-protein kinase MRCK alpha	9418861	Myotonic dystrophy kinase-related Cdc42-binding kinase acts as a Cdc42 effector in promoting cytoskeletal reorganization.

Q04726	TLE3_HUMAN	Transducin-like enhancer protein 3	1303260	Human homologs of a Drosophila enhancer of split gene product define a novel family of nuclear proteins.

P30793	GCH1_HUMAN	GTP cyclohydrolase 1	15604419	Cytokine-stimulated GTP cyclohydrolase I expression in endothelial cells requires coordinated activation of nuclear factor-kappaB and Stat1/Stat3.

Q805B2	FGF8B_DANRE	Fibroblast growth factor 8b	11091072	Overlapping and distinct functions provided by fgf17, a new zebrafish member of the Fgf8/17/18 subgroup of Fgfs.

Q61171	PRDX2_MOUSE	Peroxiredoxin-2	9714804	The type II peroxiredoxin gene family of the mouse: molecular structure, expression and evolution.

Q9HDV8	YOE2_SCHPO	Uncharacterized protein P19A11.02c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9US08	SPO3_SCHPO	Sporulation-specific protein 3	11739793	The Schizosaccharomyces pombe spo3+ gene is required for assembly of the forespore membrane and genetically interacts with psy1(+)-encoding syntaxin-like protein.

Q9MAN1	NGA3_ARATH	B3 domain-containing transcription factor NGA3	16603651	Endogenous and synthetic microRNAs stimulate simultaneous, efficient, and localized regulation of multiple targets in diverse species.

P20263	PO5F1_MOUSE	POU domain, class 5, transcription factor 1	1967980	A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells.

P22516	CHL1_YEAST	ATP-dependent RNA helicase CHL1	15020404	Chl1p, a DNA helicase-like protein in budding yeast, functions in sister-chromatid cohesion.

Q9XGM8	MGAT1_ARATH	Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	18408158	Salt tolerance of Arabidopsis thaliana requires maturation of N- glycosylated proteins in the Golgi apparatus.

P29704	FDFT_YEAST	Squalene synthase	1807826	Isolation and primary structure of the ERG9 gene of Saccharomyces cerevisiae encoding squalene synthetase.

Q05787	HRD3_YEAST	ERAD-associated E3 ubiquitin-protein ligase component HRD3	11390656	In vivo action of the HRD ubiquitin ligase complex: mechanisms of endoplasmic reticulum quality control and sterol regulation.

Q12797	ASPH_HUMAN	Aspartyl/asparaginyl beta-hydroxylase	7821814	Cloning and characterization of the human gene encoding aspartyl beta-hydroxylase.

P23141	EST1_HUMAN	Liver carboxylesterase 1	1918003	A serine esterase released by human alveolar macrophages is closely related to liver microsomal carboxylesterases.

O94244	HAT2_SCHPO	Histone acetyltransferase type B subunit 2	15369671	Mis16 and Mis18 are required for CENP-A loading and histone deacetylation at centromeres.

O36029	YEKH_SCHPO	Uncharacterized protein C4F10.17	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UQ84	EXO1_HUMAN	Exonuclease 1	11427529	The interaction of DNA mismatch repair proteins with human exonuclease I.

P37023	ACVL1_HUMAN	Serine/threonine-protein kinase receptor R3	14684682	Molecular and functional analysis identifies ALK-1 as the predominant cause of pulmonary hypertension related to hereditary haemorrhagic telangiectasia.

Q14586	ZN267_HUMAN	Zinc finger protein 267	7865130	Isolation of cDNA clones for 42 different Kruppel-related zinc finger proteins expressed in the human monoblast cell line U-937.

P06537	GCR_MOUSE	Glucocorticoid receptor	11751894	A new first step in activation of steroid receptors: hormone-induced switching of FKBP51 and FKBP52 immunophilins.

Q9SP02	CP20A_ARATH	Peptidyl-prolyl cis-trans isomerase CYP20-1	10628867	Mutations in a new Arabidopsis cyclophilin disrupt its interaction with protein phosphatase 2A.

P48145	NPBW1_HUMAN	Neuropeptides B/W receptor type 1	7590751	The cloning and chromosomal mapping of two novel human opioid- somatostatin-like receptor genes, GPR7 and GPR8, expressed in discrete areas of the brain.

O95139	NDUB6_HUMAN	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6	9760212	Molecular characterization and mutational analysis of the human B17 subunit of the mitochondrial respiratory chain complex I.

P84022	SMAD3_HUMAN	Mothers against decapentaplegic homolog 3	18568018	TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal.

P19456	PMA2_ARATH	ATPase 2, plasma membrane-type	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q07157	ZO1_HUMAN	Tight junction protein ZO-1	12154091	Molecular cloning, functional expression, and tissue distribution of a novel human gap junction-forming protein, connexin-31.9. Interaction with zona occludens protein-1.

O14777	NDC80_HUMAN	Kinetochore protein NDC80 homolog	14699129	Identification of two novel components of the human NDC80 kinetochore complex.

Q9UL59	ZN214_HUMAN	Zinc finger protein 214	10762538	Disruption of a novel imprinted zinc-finger gene, ZNF215, in Beckwith-Wiedemann syndrome.

Q9C5Q2	AI5L3_ARATH	ABSCISIC ACID-INSENSITIVE 5-like protein 3	15642716	Characterization of three homologous basic leucine zipper transcription factors (bZIP) of the ABI5 family during Arabidopsis thaliana embryo maturation.

Q8VZ80	PLT5_ARATH	Polyol transporter 5	15525644	Analysis of transport activity of Arabidopsis sugar alcohol permease homolog AtPLT5.

Q6NPF9	TRXY1_ARATH	Thioredoxin Y1, chloroplastic	19259774	A novel extended family of stromal thioredoxins.

Q13505	MTX1_HUMAN	Metaxin-1	8660965	Structure and organization of the human metaxin gene (MTX) and pseudogene.

Q944Q0	WNK8_ARATH	Serine/threonine-protein kinase WNK8	16427632	A WNK kinase binds and phosphorylates V-ATPase subunit C.

Q9LX82	MYB48_ARATH	Transcription factor MYB48	16531467	A subgroup of MYB transcription factor genes undergoes highly conserved alternative splicing in Arabidopsis and rice.

O59759	YJM5_SCHPO	Uncharacterized protein C1020.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9LFB8	PTR5_ARATH	Peptide transporter PTR5	18753286	AtPTR1 and AtPTR5 transport dipeptides in planta.

P09875	UD2B1_RAT	UDP-glucuronosyltransferase 2B1	3084479	Rat liver UDP-glucuronosyltransferase. Sequence and expression of a cDNA encoding a phenobarbital-inducible form.

P49411	EFTU_HUMAN	Elongation factor Tu, mitochondrial	9332382	The human mitochondrial elongation factor Tu (EF-Tu) gene: cDNA sequence, genomic localization, genomic structure, and identification of a pseudogene.

Q28685	DAG1_RABIT	Dystroglycan	1741056	Primary structure of dystrophin-associated glycoproteins linking dystrophin to the extracellular matrix.

Q9HGL2	YHLA_SCHPO	Uncharacterized calcium-binding protein C800.10c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P46527	CDN1B_HUMAN	Cyclin-dependent kinase inhibitor 1B	12093740	A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression.

P09525	ANXA4_HUMAN	Annexin A4	2970257	Isolation and expression of cDNA coding for a new member of the phospholipase A2 inhibitor family.

Q06168	SFH1_YEAST	Chromatin structure-remodeling complex subunit SFH1	12697820	The yeast RSC chromatin-remodeling complex is required for kinetochore function in chromosome segregation.

Q9NSA0	S22AB_HUMAN	Solute carrier family 22 member 11	10660625	Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta.

Q03164	MLL1_HUMAN	Histone-lysine N-methyltransferase MLL	15199122	Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression.

P61247	RS3A_HUMAN	40S ribosomal protein S3a	1398113	Human ribosomal protein S3a: cloning of the cDNA and primary structure of the protein.

P04551	CDK1_SCHPO	Cell division control protein 2	8855663	A quantitative model for the cdc2 control of S phase and mitosis in fission yeast.

P0AD89	LPTN_ECOLI	Tryptophanase leader peptide	3902796	Evidence for transcription antitermination control of tryptophanase operon expression in Escherichia coli K-12.

Q63342	M2GD_RAT	Dimethylglycine dehydrogenase, mitochondrial	1710985	Rat liver dimethylglycine dehydrogenase. Flavinylation of the enzyme in hepatocytes in primary culture and characterization of a cDNA clone.

P00127	QCR6_YEAST	Cytochrome b-c1 complex subunit 6	10873857	Structure at 2.3 A resolution of the cytochrome bc1 complex from the yeast Saccharomyces cerevisiae co-crystallized with an antibody Fv fragment.

P40065	MAM1_YEAST	Monopolin complex subunit MAM1	12663816	Role of Polo-like kinase CDC5 in programming meiosis I chromosome segregation.

Q9Y5U4	INSI2_HUMAN	Insulin-induced gene 2 protein	12242332	Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins.

Q9NHD5	SAN_DROME	Probable N-acetyltransferase san	14653991	Two putative acetyltransferases, san and deco, are required for establishing sister chromatid cohesion in Drosophila.

P53904	TBCB_YEAST	Tubulin-specific chaperone B	9885248	Alf1p, a CLIP-170 domain-containing protein, is functionally and physically associated with alpha-tubulin.

Q7XQ12	AMT11_ORYSJ	Ammonium transporter 1 member 1	12610225	Constitutive expression of a novel-type ammonium transporter OsAMT2 in rice plants.

Q9UHD8	SEPT9_HUMAN	Septin-9	10339604	MSF (MLL septin-like fusion), a fusion partner gene of MLL, in a therapy-related acute myeloid leukemia with a t(11;17)(q23;q25).

Q9FLL4	PUP12_ARATH	Putative purine permease 12	10662864	A new family of high-affinity transporters for adenine, cytosine, and purine derivatives in Arabidopsis.

Q9BVP2	GNL3_HUMAN	Guanine nucleotide-binding protein-like 3	12464630	A nucleolar mechanism controlling cell proliferation in stem and cancer cells.

P11350	NARI_ECOLI	Respiratory nitrate reductase 1 gamma chain	3053688	Roles of the narJ and narI gene products in the expression of nitrate reductase in Escherichia coli.

Q94JQ6	CESA6_ARATH	Cellulose synthase A catalytic subunit 6 [UDP-forming]	16627697	Visualization of cellulose synthase demonstrates functional association with microtubules.

Q8IVB4	SL9A9_HUMAN	Sodium/hydrogen exchanger 9	15522866	Four Na+/H+ exchanger isoforms are distributed to Golgi and post- Golgi Compartments and are involved in organelle pH regulation.

Q9BZZ5	API5_HUMAN	Apoptosis inhibitor 5	11075807	FIF [fibroblast growth factor-2 (FGF-2)-interacting-factor], a nuclear putatively antiapoptotic factor, interacts specifically with FGF-2.

Q8CGU1	CACO1_MOUSE	Calcium-binding and coiled-coil domain-containing protein 1	14690606	CoCoA, a nuclear receptor coactivator which acts through an N- terminal activation domain of p160 coactivators.

P35169	TOR1_YEAST	Serine/threonine-protein kinase TOR1	8186460	TOR1 and TOR2 are structurally and functionally similar but not identical phosphatidylinositol kinase homologues in yeast.

O00294	TULP1_HUMAN	Tubby-related protein 1	16303976	Tubby-like protein 1 (TULP1) interacts with F-actin in photoreceptor cells.

Q9LKL2	APRR1_ARATH	Two-component response regulator-like APRR1	19286557	A functional genomics approach reveals CHE as a component of the Arabidopsis circadian clock.

Q99PD6	TGFI1_RAT	Transforming growth factor beta-1-induced transcript 1 protein	11546764	Identification and characterization of hic-5/ARA55 as an hsp27 binding protein.

P46644	AAT3_ARATH	Aspartate aminotransferase, chloroplastic	7894512	The aspartate aminotransferase gene family of Arabidopsis encodes isoenzymes localized to three distinct subcellular compartments.

P13085	PTHR_RAT	Parathyroid hormone-related protein	3175653	Expression of a calcium-mobilizing parathyroid hormone-like peptide in lactating mammary tissue.

O60763	USO1_HUMAN	General vesicular transport factor p115	9478999	Phosphorylation of the vesicle docking protein p115 regulates its association with the Golgi membrane.

Q8CE90	MP2K7_MOUSE	Dual specificity mitogen-activated protein kinase kinase 7	9891090	The MKK7 gene encodes a group of c-Jun NH2-terminal kinase kinases.

Q8STE5	CED12_CAEEL	Cell death abnormality protein 12	15620647	Phagocytosis of apoptotic cells is regulated by a UNC-73/TRIO-MIG- 2/RhoG signaling module and armadillo repeats of CED-12/ELMO.

Q14872	MTF1_HUMAN	Metal regulatory transcription factor 1	8065932	Cloning, chromosomal mapping and characterization of the human metal- regulatory transcription factor MTF-1.

Q9SA96	AROD1_ARATH	Arogenate dehydratase/prephenate dehydratase 1, chloroplastic	19136569	Tyrosine and phenylalanine are synthesized within the plastids in Arabidopsis.

Q9VSL7	FOI_DROME	Zinc transporter foi	15509557	Drosophila fear of intimacy encodes a Zrt/IRT-like protein (ZIP) family zinc transporter functionally related to mammalian ZIP proteins.

Q495A1	TIGIT_HUMAN	T cell immunoreceptor with Ig and ITIM domains	19011627	The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.

Q92769	HDAC2_HUMAN	Histone deacetylase 2	11739383	Isolation and characterization of a novel class II histone deacetylase, HDAC10.

Q9SYM4	TPS1_ARATH	Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 1	15667325	Trehalose metabolism and glucose sensing in plants.

B5A5T4	QVR_DROME	Protein quiver	18635795	Identification of SLEEPLESS, a sleep-promoting factor.

Q04839	GFD1_YEAST	mRNA transport factor GFD1	15619606	Physical and genetic interactions link the yeast protein Zds1p with mRNA nuclear export.

Q9NSU2	TREX1_HUMAN	Three prime repair exonuclease 1	11278605	Structure and expression of the TREX1 and TREX2 3'-->5' exonuclease genes.

P47924	RIBBA_ARATH	Riboflavin biosynthesis protein ribBA, chloroplastic	7642114	Isolation of cDNAs encoding GTP cyclohydrolase II from Arabidopsis thaliana.

P0AFC7	NUOB_ECOLI	NADH-quinone oxidoreductase subunit B	7607227	Isolation and characterization of the proton-translocating NADH: ubiquinone oxidoreductase from Escherichia coli.

P21674	FST_RAT	Follistatin	2725528	Follistatin gene expression in the ovary and extragonadal tissues.

Q9USU3	FBH1_SCHPO	F-box DNA helicase protein 1	9228070	A DNA helicase from Schizosaccharomyces pombe stimulated by single- stranded DNA-binding protein at low ATP concentration.

Q5RKH6	OS9_RAT	Protein OS-9	19084021	Mammalian OS-9 is upregulated in response to endoplasmic reticulum stress and facilitates ubiquitination of misfolded glycoproteins.

P92981	APR2_ARATH	5'-adenylylsulfate reductase 2, chloroplastic	8917600	Sulfate reduction in higher plants: molecular evidence for a novel 5'-adenylylsulfate reductase.

P0AGF6	THD2_ECOLI	Threonine dehydratase catabolic	6751404	Chemical characterization of biodegradative threonine dehydratases from two enteric bacteria.

O75452	RDH16_HUMAN	Retinol dehydrogenase 16	9677409	cDNA cloning and characterization of a new human microsomal NAD+- dependent dehydrogenase that oxidizes all-trans-retinol and 3alpha- hydroxysteroids.

Q04082	GPI19_YEAST	Phosphatidylinositol N-acetylglucosaminyltransferase subunit GPI19	16278447	Gpi19, the Saccharomyces cerevisiae homologue of mammalian PIG-P, is a subunit of the initial enzyme for glycosylphosphatidylinositol anchor biosynthesis.

O04089	ZIP4_ARATH	Zinc transporter 4, chloroplastic	13129917	Expression profiles of Arabidopsis thaliana in mineral deficiencies reveal novel transporters involved in metal homeostasis.

P15731	UBC4_YEAST	Ubiquitin-conjugating enzyme E2 4	17550898	A conserved cysteine is essential for Pex4p-dependent ubiquitination of the peroxisomal import receptor Pex5p.

P14284	DPOZ_YEAST	DNA polymerase zeta catalytic subunit	8658138	Thymine-thymine dimer bypass by yeast DNA polymerase zeta.

Q9P0M6	H2AW_HUMAN	Core histone macro-H2A.2	11331621	Histone H2A variants and the inactive X chromosome: identification of a second macroH2A variant.

Q9Y272	RASD1_HUMAN	Dexamethasone-induced Ras-related protein 1	10471929	Genetic screens in yeast to identify mammalian nonreceptor modulators of G-protein signaling.

Q03782	SNU56_YEAST	56 kDa U1 small nuclear ribonucleoprotein component	10072386	Identification of eight proteins that cross-link to pre-mRNA in the yeast commitment complex.

Q8W115	PR1A3_ARATH	PRA1 family protein A3	18583532	The PRA1 gene family in Arabidopsis.

Q9HGP8	YM04_SCHPO	UPF0494 membrane protein C212.04c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P33157	E13A_ARATH	Glucan endo-1,3-beta-glucosidase, acidic isoform	1392589	Acquired resistance in Arabidopsis.

Q60575	KIF1B_MOUSE	Kinesin-like protein KIF1B	7528108	KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondria.

Q13952	NFYC_HUMAN	Nuclear transcription factor Y subunit gamma	12401788	The NF-YB/NF-YC structure gives insight into DNA binding and transcription regulation by CCAAT factor NF-Y.

P83519	LECG_BOTJR	Galactose-specific lectin	11478954	Effect of BJcuL (a lectin from the venom of the snake Bothrops jararacussu) on adhesion and growth of tumor and endothelial cells.

P39206	CAIE_ECOLI	Carnitine operon protein CaiE	7815937	Molecular characterization of the cai operon necessary for carnitine metabolism in Escherichia coli.

Q54PF3	CSN5_DICDI	COP9 signalosome complex subunit 5	16781008	The COP9 signalosome regulates cell proliferation of Dictyostelium discoideum.

Q9WUH5	TRI10_MOUSE	Tripartite motif-containing protein 10	11331580	The tripartite motif family identifies cell compartments.

P48163	MAOX_HUMAN	NADP-dependent malic enzyme	8187880	Characterization of cytosolic malic enzyme in human tumor cells.

P25390	SSK22_YEAST	Serine/threonine-protein kinase SSK22	7624781	Activation of yeast PBS2 MAPKK by MAPKKKs or by binding of an SH3- containing osmosensor.

Q06266	TOS4_YEAST	Protein TOS4	12464632	Complex transcriptional circuitry at the G1/S transition in Saccharomyces cerevisiae.

O35276	NRP2_RAT	Neuropilin-2	9288754	Neuropilin is a semaphorin III receptor.

Q12339	UTP23_YEAST	rRNA-processing protein UTP23	14690591	Assigning function to yeast proteins by integration of technologies.

P33416	HSP78_YEAST	Heat shock protein 78, mitochondrial	8830768	The molecular chaperone Hsp78 confers compartment-specific thermotolerance to mitochondria.

P62873	GBB1_HUMAN	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	3095147	Beta-subunits of the human liver Gs/Gi signal-transducing proteins and those of bovine retinal rod cell transducin are identical.

P01718	LV404_HUMAN	Ig lambda chain V-IV region Kern	5549568	Structural rule of antibodies. Primary structure of a monoclonal immunoglobulin-L-chain of the lambda type, subgroup IV (Bence-Jones- protein Kern). V. The complete amino acid sequence and its genetic interpretation.

Q8WXH0	SYNE2_HUMAN	Nesprin-2	19933576	Mammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processes.

Q08108	PLB3_YEAST	Lysophospholipase 3	10497163	Characterization and function in vivo of two novel phospholipases B/lysophospholipases from Saccharomyces cerevisiae.

Q9I234	KYNB_PSEAE	Kynurenine formamidase	14592712	Aerobic tryptophan degradation pathway in bacteria: novel kynurenine formamidase.

Q9WV93	HEY1_MOUSE	Hairy/enhancer-of-split related with YRPW motif protein 1	14648848	Identification of BOIP, a novel cDNA highly expressed during spermatogenesis that encodes a protein interacting with the orange domain of the hairy-related transcription factor HRT1/Hey1 in Xenopus and mouse.

P35637	FUS_HUMAN	RNA-binding protein FUS	8510758	Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma.

Q8C1B2	PARPT_MOUSE	TCDD-inducible poly [ADP-ribose] polymerase	11716501	TCDD-inducible poly(ADP-ribose) polymerase: a novel response to 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Q09175	KRP1_SCHPO	Dibasic-processing endoprotease	7813430	Isolation and characterization of krp, a dibasic endopeptidase required for cell viability in the fission yeast Schizosaccharomyces pombe.

Q8T940	UBX_JUNCO	Homeotic protein ultrabithorax	7840822	Evolution of homeotic gene regulation and function in flies and butterflies.

Q19564	OXDD1_CAEEL	D-aspartate oxidase 1	17140416	Caenorhabditis elegans has two genes encoding functional D-aspartate oxidases.

Q9M1X5	ASK13_ARATH	SKP1-like protein 13	14749489	Expression and interaction analysis of Arabidopsis Skp1-related genes.

Q99615	DNJC7_HUMAN	DnaJ homolog subfamily C member 7	18620420	Role of the cochaperone Tpr2 in Hsp90 chaperoning.

Q9NRS4	TMPS4_HUMAN	Transmembrane protease serine 4	10825129	A novel transmembrane serine protease (TMPRSS3) overexpressed in pancreatic cancer.

Q9NXR7	BRE_HUMAN	BRCA1-A complex subunit BRE	19261748	MERIT40 facilitates BRCA1 localization and DNA damage repair.

P32523	PRP19_YEAST	Pre-mRNA-splicing factor 19	8194532	Functional association of essential splicing factor(s) with PRP19 in a protein complex.

P18886	CPT2_RAT	Carnitine O-palmitoyltransferase 2, mitochondrial	16781677	Crystal structure of rat carnitine palmitoyltransferase II (CPT- II).

P19493	GRIA4_RAT	Glutamate receptor 4	2166337	A family of AMPA-selective glutamate receptors.

P91938	TRXR1_DROME	Thioredoxin reductase 1, mitochondrial	11877442	Thioredoxin-2 but not thioredoxin-1 is a substrate of thioredoxin peroxidase-1 from Drosophila melanogaster: isolation and characterization of a second thioredoxin in D.melanogaster and evidence for distinct biological functions of Trx-1 and Trx-2.

P0A742	MSCL_ECOLI	Large-conductance mechanosensitive channel	7511799	A large-conductance mechanosensitive channel in E. coli encoded by mscL alone.

Q9WUU6	HNF4G_MOUSE	Hepatocyte nuclear factor 4-gamma	10786614	Primary structure, chromosomal mapping, expression and transcriptional activity of murine hepatocyte nuclear factor 4gamma.

Q9UPX8	SHAN2_HUMAN	SH3 and multiple ankyrin repeat domains protein 2	10506216	Characterization of the shank family of synaptic proteins. Multiple genes, alternative splicing, and differential expression in brain and development.

P31751	AKT2_HUMAN	RAC-beta serine/threonine-protein kinase	1409633	AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas.

Q15078	CD5R1_HUMAN	Cyclin-dependent kinase 5 activator 1	8090221	p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5.

P19020	DRD3_RAT	D(3) dopamine receptor	14499480	CLIC6, a member of the intracellular chloride channel family, interacts with dopamine D(2)-like receptors.

P18418	CALR_RAT	Calreticulin	12782144	Calreticulin -- an endoplasmic reticulum protein with calcium-binding activity is also found in the extracellular matrix.

Q9Y6I4	UBP3_HUMAN	Ubiquitin carboxyl-terminal hydrolase 3	17980597	Human USP3 is a chromatin modifier required for S phase progression and genome stability.

Q99P25	TXIP1_MOUSE	Translin-associated factor X-interacting protein 1	12036294	Identification and characterization of cDNAs encoding four novel proteins that interact with translin associated factor-X.

Q8I7Z8	HAM_DROME	Transcription factor hamlet	12193790	Hamlet, a binary genetic switch between single- and multiple-dendrite neuron morphology.

Q03818	ATG16_YEAST	Autophagy protein 16	11897782	Formation of the approximately 350-kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast.

P56381	ATP5E_HUMAN	ATP synthase subunit epsilon, mitochondrial	10727396	Cloning, characterization and mapping of the human ATP5E gene, identification of pseudogene ATP5EP1, and definition of the ATP5E motif.

O15393	TMPS2_HUMAN	Transmembrane protease serine 2	9325052	Cloning of the TMPRSS2 gene, which encodes a novel serine protease with transmembrane, LDLRA, and SRCR domains and maps to 21q22.3.

P36154	AIM29_YEAST	Altered inheritance rate of mitochondria protein 29	11914276	Subcellular localization of the yeast proteome.

P35527	K1C9_HUMAN	Keratin, type I cytoskeletal 9	8647270	Keratin 9 point mutation in the pedigree of epidermolytic hereditary palmoplantar keratoderma perturbs keratin intermediate filament network formation.

P36575	ARRC_HUMAN	Arrestin-C	8224247	X-arrestin: a new retinal arrestin mapping to the X chromosome.

Q9QXV0	PCSK1_MOUSE	ProSAAS	16631141	Quantification of VGF- and pro-SAAS-derived peptides in endocrine tissues and the brain, and their regulation by diet and cold stress.

P46676	SUM1_YEAST	Suppressor of mar1-1 protein	10562556	Sum1 and Hst1 repress middle sporulation-specific gene expression during mitosis in Saccharomyces cerevisiae.

Q682S0	RPT2_ARATH	Root phototropism protein 2	10662859	RPT2: a signal transducer of the phototropic response in Arabidopsis.

Q04049	POLH_YEAST	DNA polymerase eta	11027270	Replication past O(6)-methylguanine by yeast and human DNA polymerase eta.

Q9UQ49	NEUR3_HUMAN	Sialidase-3	10405317	Cloning, expression, and chromosomal mapping of a human ganglioside sialidase.

Q06003	GOLI_DROME	Protein goliath	8462875	The Drosophila melanogaster developmental gene g1 encodes a variant zinc-finger-motif protein.

Q62770	UN13C_RAT	Protein unc-13 homolog C	7559667	Mammalian homologues of Caenorhabditis elegans unc-13 gene define novel family of C2-domain proteins.

P07253	CBP6_YEAST	Cytochrome B pre-mRNA-processing protein 6	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P54681	RTOA_DICDI	Protein rtoA	10747962	A protein containing a serine-rich domain with vesicle fusing properties mediates cell cycle-dependent cytosolic pH regulation.

P02545	LMNA_HUMAN	Prelamin-A/C	10514485	Prenylated prelamin A interacts with Narf, a novel nuclear protein.

Q9UKD1	GMEB2_HUMAN	Glucocorticoid modulatory element-binding protein 2	10523663	Two new members of the emerging KDWK family of combinatorial transcription modulators bind as a heterodimer to flexibly spaced PuCGPy half-sites.

P31362	PO2F3_MOUSE	POU domain, class 2, transcription factor 3	8224904	Epoc-1: a POU-domain gene expressed in murine epidermal basal cells and thymic stromal cells.

Q02933	RNY1_YEAST	Ribonuclease T2-like	19332891	The RNase Rny1p cleaves tRNAs and promotes cell death during oxidative stress in Saccharomyces cerevisiae.

Q9ULX3	NOB1_HUMAN	RNA-binding protein NOB1	15231747	A protein interaction framework for human mRNA degradation.

P53778	MK12_HUMAN	Mitogen-activated protein kinase 12	10508788	The structure of phosphorylated p38gamma is monomeric and reveals a conserved activation-loop conformation.

Q42484	RPS2_ARATH	Disease resistance protein RPS2	8091210	RPS2 of Arabidopsis thaliana: a leucine-rich repeat class of plant disease resistance genes.

Q9HG09	PEX14_PICPA	Peroxisomal membrane protein PEX14	11329173	Pichia pastoris Pex14p, a phosphorylated peroxisomal membrane protein, is part of a PTS-receptor docking complex and interacts with many peroxins.

Q8TDD1	DDX54_HUMAN	ATP-dependent RNA helicase DDX54	12466272	Regulation of nuclear receptor transcriptional activity by a novel DEAD box RNA helicase (DP97).

Q63617	HYOU1_RAT	Hypoxia up-regulated protein 1	8617779	Purification and characterization of a novel stress protein, the 150- kDa oxygen-regulated protein (ORP150), from cultured rat astrocytes and its expression in ischemic mouse brain.

P53881	RM22_YEAST	54S ribosomal protein L22, mitochondrial	12392552	Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components.

Q8QGV6	NLK2_XENLA	Serine/threonine-protein kinase NLK2	15004007	Role of the TAK1-NLK-STAT3 pathway in TGF-beta-mediated mesoderm induction.

Q9VFI9	PDE6_DROME	cGMP-specific 3',5'-cyclic phosphodiesterase	16232123	A novel role for a Drosophila homologue of cGMP-specific phosphodiesterase in the active transport of cGMP.

P32629	ANP1_YEAST	Mannan polymerase II complex ANP1 subunit	9434768	Novel membrane protein complexes for protein glycosylation in the yeast Golgi apparatus.

P47061	VPS53_YEAST	Vacuolar protein sorting-associated protein 53	12377769	Vps51p links the VFT complex to the SNARE Tlg1p.

Q12212	SIA1_YEAST	Protein SIA1	9450541	Yeast gene YOR137c is involved in the activation of the yeast plasma membrane H+-ATPase by glucose.

Q9N2I8	TRXR2_BOVIN	Thioredoxin reductase 2, mitochondrial	10447675	Mitochondrial thioredoxin reductase in bovine adrenal cortex. Its purification, properties, nucleotide/amino acid sequences, and identification of selenocysteine.

P40474	QDR2_YEAST	Quinidine resistance protein 2	15215105	Saccharomyces cerevisiae multidrug transporter Qdr2p (Yil121wp): localization and function as a quinidine resistance determinant.

O14893	GEMI2_HUMAN	Survival of motor neuron protein-interacting protein 1	11714716	Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins.

P53866	SQS1_YEAST	Protein SQS1	14562095	Global analysis of protein localization in budding yeast.

P11030	ACBP_RAT	Acyl-CoA-binding protein	7690962	Cloning and tissue-specific functional characterization of the promoter of the rat diazepam binding inhibitor, a peptide with multiple biological actions.

P07256	QCR1_YEAST	Cytochrome b-c1 complex subunit 1, mitochondrial	11502169	Yeast mitochondrial dehydrogenases are associated in a supramolecular complex.

Q8S307	BZR1_ARATH	Protein BRASSINAZOLE-RESISTANT 1	11970900	Nuclear-localized BZR1 mediates brassinosteroid-induced growth and feedback suppression of brassinosteroid biosynthesis.

Q8RVQ9	HTR12_ARATH	Histone H3-like centromeric protein HTR12	12034896	Centromeric localization and adaptive evolution of an Arabidopsis histone H3 variant.

Q21227	APR1_CAEEL	Adenomatous polyposis coli protein-related protein 1	12023306	Activation of Wnt signaling bypasses the requirement for RTK/Ras signaling during C. elegans vulval induction.

Q9W032	SGT1_DROME	Protein SGT1 homolog ecdysoneless	15128659	Cell-autonomous roles of the ecdysoneless gene in Drosophila development and oogenesis.

Q86PM2	KMO_AEDAE	Kynurenine 3-monooxygenase	12974953	Analysis of the wild-type and mutant genes encoding the enzyme kynurenine monooxygenase of the yellow fever mosquito, Aedes aegypti.

P21579	SYT1_HUMAN	Synaptotagmin-1	1840599	Structural and functional conservation of synaptotagmin (p65) in Drosophila and humans.

O15269	SPTC1_HUMAN	Serine palmitoyltransferase 1	20182505	Orm family proteins mediate sphingolipid homeostasis.

O60506	HNRPQ_HUMAN	Heterogeneous nuclear ribonucleoprotein Q	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

Q8WYP3	RIN2_HUMAN	Ras and Rab interactor 2	11733506	A novel binding protein composed of homophilic tetramer exhibits unique properties for the small GTPase Rab5.

Q0GGX2	ZN541_MOUSE	Zinc finger protein 541	17662146	Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.

Q90240	CBPD_ANAPL	Carboxypeptidase D	9525948	gp180, a protein that binds duck hepatitis B virus particles, has metallocarboxypeptidase D-like enzymatic activity.

P61803	DAD1_HUMAN	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1	8413235	Molecular cloning of a human cDNA encoding a novel protein, DAD1, whose defect causes apoptotic cell death in hamster BHK21 cells.

Q8BFU8	VGLU3_MOUSE	Vesicular glutamate transporter 3	12384506	Molecular cloning and functional identification of mouse vesicular glutamate transporter 3 and its expression in subsets of novel excitatory neurons.

P43124	NSE4_YEAST	Non-structural maintenance of chromosome element 4	15752197	Qri2/Nse4, a component of the essential Smc5/6 DNA repair complex.

Q9VFJ3	HTRA2_DROME	Serine protease HTRA2, mitochondrial	17557079	Drosophila Omi, a mitochondrial-localized IAP antagonist and proapoptotic serine protease.

Q6PUA2	TAF1B_ARATH	Transcription initiation factor TFIID subunit 1-B	15525647	Arabidopsis HAF2 gene encoding TATA-binding protein (TBP)-associated factor TAF1, is required to integrate light signals to regulate gene expression and growth.

P43699	NKX21_HUMAN	Homeobox protein Nkx-2.1	11971878	Mutations in TITF-1 are associated with benign hereditary chorea.

Q8W2B8	SAT4_ARATH	Serine acetyltransferase 4	15579666	Characterization and expression analysis of a serine acetyltransferase gene family involved in a key step of the sulfur assimilation pathway in Arabidopsis.

Q9LUT2	METK4_ARATH	S-adenosylmethionine synthase 4	16574749	Proteome analysis of cold stress response in Arabidopsis thaliana using DIGE-technology.

Q9C005	DPY30_HUMAN	Protein dpy-30 homolog	19651892	A role of histone H3 lysine 4 methyltransferase components in endosomal trafficking.

P23638	PSA4_YEAST	Proteasome component Y13	9087403	Structure of 20S proteasome from yeast at 2.4-A resolution.

Q9H0E9	BRD8_HUMAN	Bromodomain-containing protein 8	8611617	Cloning and sequencing of a human cDNA encoding a putative transcription factor containing a bromodomain.

O43157	PLXB1_HUMAN	Plexin-B1	8570614	A family of transmembrane proteins with homology to the MET- hepatocyte growth factor receptor.

Q9LNR3	LOX3_ARATH	Lipoxygenase 3, chloroplastic	17786451	Identification and characterization of COI1-dependent transcription factor genes involved in JA-mediated response to wounding in Arabidopsis plants.

Q5TC12	ATPF1_HUMAN	ATP synthase mitochondrial F1 complex assembly factor 1	11410595	Atp11p and Atp12p are assembly factors for the F(1)-ATPase in human mitochondria.

Q17784	TFP11_CAEEL	Septin and tuftelin-interacting protein 1 homolog	17289020	Characterization of STIP, a multi-domain nuclear protein, highly conserved in metazoans, and essential for embryogenesis in Caenorhabditis elegans.

Q84WU4	GOGC3_ARATH	Golgin candidate 3	18182439	Localization and domain characterization of Arabidopsis golgin candidates.

Q21067	IFC2_CAEEL	Intermediate filament protein ifc-2	12204276	Expression profiles of the essential intermediate filament (IF) protein A2 and the IF protein C2 in the nematode Caenorhabditis elegans.

P56693	SOX10_HUMAN	Transcription factor SOX-10	9722528	Functional analysis of Sox10 mutations found in human Waardenburg- Hirschsprung patients.

P10242	MYB_HUMAN	Transcriptional activator Myb	3014652	Studies of the human c-myb gene and its product in human acute leukemias.

Q02887	ATG21_YEAST	Autophagy-related protein 21	11852075	Mai1p is essential for maturation of proaminopeptidase I but not for autophagy.

Q93074	MED12_HUMAN	Mediator of RNA polymerase II transcription subunit 12	10235267	Composite co-activator ARC mediates chromatin-directed transcriptional activation.

P49459	UBE2A_HUMAN	Ubiquitin-conjugating enzyme E2 A	1717990	Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6.

Q6PIY7	GLD2_HUMAN	Poly(A) RNA polymerase GLD2	18172165	Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'.

Q9URQ5	HTL1_YEAST	High temperature lethal protein 1	12417720	HTL1 encodes a novel factor that interacts with the RSC chromatin remodeling complex in Saccharomyces cerevisiae.

Q9LY15	MSRA2_ARATH	Peptide methionine sulfoxide reductase A2	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

P23363	BDNF_RAT	Brain-derived neurotrophic factor	1889806	Human and rat brain-derived neurotrophic factor and neurotrophin-3: gene structures, distributions, and chromosomal localizations.

P11609	CD1D1_MOUSE	Antigen-presenting glycoprotein CD1d1	11754812	CD1d endosomal trafficking is independently regulated by an intrinsic CD1d-encoded tyrosine motif and by the invariant chain.

P36405	ARL3_HUMAN	ADP-ribosylation factor-like protein 3	8034651	ADP-ribosylation factor (ARF)-like 3, a new member of the ARF family of GTP-binding proteins cloned from human and rat tissues.

P31434	XYLS_ECOLI	Alpha-xylosidase	15294295	Overexpression and characterization of two unknown proteins, YicI and YihQ, originated from Escherichia coli.

Q64512	PTN13_MOUSE	Tyrosine-protein phosphatase non-receptor type 13	10526152	Identification and molecular characterization of BP75, a novel bromodomain-containing protein.

Q6IMI6	ST1C3_HUMAN	Sulfotransferase 1C3	17936463	SULT1C3, an orphan sequence of the human genome, encodes an enzyme activating various promutagens.

P00505	AATM_HUMAN	Aspartate aminotransferase, mitochondrial	4052435	The primary structure of mitochondrial aspartate aminotransferase from human heart.

Q06671	ATG23_YEAST	Autophagy-related protein 23	14734026	ATG23, a novel gene required for maturation of proaminopeptidase I, but not for autophagy.

P07649	TRUA_ECOLI	tRNA pseudouridine synthase A	3276686	Purification, structure, and properties of Escherichia coli tRNA pseudouridine synthase I.

P23467	PTPRB_HUMAN	Receptor-type tyrosine-protein phosphatase beta	19167335	Large-scale structural analysis of the classical human protein tyrosine phosphatome.

Q1MTR4	CTI6_SCHPO	Putative histone deacetylase complex subunit cti6	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

Q9H492	MLP3A_HUMAN	Microtubule-associated proteins 1A/1B light chain 3A	15187094	HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtubule-associated protein light chain 3- and GABAA receptor-associated protein-phospholipid conjugates.

Q9ESG5	HS3S1_RAT	Heparan sulfate glucosamine 3-O-sulfotransferase 1	10926552	Expression of N-deacetylase/sulfotransferase and 3-O-sulfotransferase in rat alveolar type II cells.

Q6NZI2	PTRF_HUMAN	Polymerase I and transcript release factor	17026959	Association and insulin regulated translocation of hormone-sensitive lipase with PTRF.

Q8H0W1	PLSP1_ARATH	Chloroplast processing peptidase	16275749	Complete maturation of the plastid protein translocation channel requires a type I signal peptidase.

Q8IWX8	CHERP_HUMAN	Calcium homeostasis endoplasmic reticulum protein	8896557	Cloning of the gene for spinocerebellar ataxia 2 reveals a locus with high sensitivity to expanded CAG/glutamine repeats.

Q9JLB5	ACH10_RAT	Neuronal acetylcholine receptor subunit alpha-10	12117536	The alpha9alpha10 nicotinic acetylcholine receptor is permeable to and is modulated by divalent cations.

Q96RU7	TRIB3_HUMAN	Tribbles homolog 3	15299019	Human tribbles, a protein family controlling mitogen-activated protein kinase cascades.

Q07896	NOC3_YEAST	Nucleolar complex-associated protein 3	12110182	Noc3p, a bHLH protein, plays an integral role in the initiation of DNA replication in budding yeast.

P97473	TRBP2_MOUSE	RISC-loading complex subunit TARBP2	17452327	Human TRBP and PACT directly interact with each other and associate with dicer to facilitate the production of small interfering RNA.

Q9H0H5	RGAP1_HUMAN	Rac GTPase-activating protein 1	12689593	Phosphorylation by aurora B converts MgcRacGAP to a RhoGAP during cytokinesis.

Q92922	SMRC1_HUMAN	SWI/SNF complex subunit SMARCC1	11238380	Purification and characterization of mSin3A-containing Brg1 and hBrm chromatin remodeling complexes.

P17735	ATTY_HUMAN	Tyrosine aminotransferase	7999802	Cloning and expression of human tyrosine aminotransferase cDNA.

O95136	S1PR2_HUMAN	Sphingosine 1-phosphate receptor 2	10617617	Sphingosine 1-phosphate-induced cell proliferation, survival, and related signaling events mediated by G protein-coupled receptors Edg3 and Edg5.

O60921	HUS1_HUMAN	Checkpoint protein HUS1	9878245	cDNA cloning and gene mapping of human homologs for Schizosaccharomyces pombe rad17, rad1, and hus1 and cloning of homologs from mouse, Caenorhabditis elegans, and Drosophila melanogaster.

Q9Z2Y9	KLOT_RAT	Klotho	9791011	Molecular cloning of rat klotho cDNA: markedly decreased expression of klotho by acute inflammatory stress.

Q9Y7R7	RL1DA_SCHPO	Putative ribosome biogenesis protein C306.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O75940	SPF30_HUMAN	Survival of motor neuron-related-splicing factor 30	9817934	Characterization of a gene encoding survival motor neuron (SMN)- related protein, a constituent of the spliceosome complex.

P56545	CTBP2_HUMAN	C-terminal-binding protein 2	9479502	A novel C-terminal binding protein (CTBP2) is closely related to CTBP1, an adenovirus E1A-binding protein, and maps to human chromosome 21q21.3.

Q9NUN7	ACER3_HUMAN	Alkaline ceramidase 3	11356846	Cloning and characterization of a novel human alkaline ceramidase. A mammalian enzyme that hydrolyzes phytoceramide.

Q9H257	CARD9_HUMAN	Caspase recruitment domain-containing protein 9	11053425	CARD9 is a novel caspase recruitment domain-containing protein that interacts with Bcl10/CLAP and activates NF-kappa B.

P28224	MLIC_ECOLI	Membrane-bound lysozyme inhibitor of C-type lysozyme	18369469	A new family of lysozyme inhibitors contributing to lysozyme tolerance in Gram-negative bacteria.

O13755	FRDS_SCHPO	Putative fumarate reductase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P38629	RFC3_YEAST	Replication factor C subunit 3	11389843	Identification of RFC(Ctf18p, Ctf8p, Dcc1p): an alternative RFC complex required for sister chromatid cohesion in S. cerevisiae.

Q6ZNE5	BAKOR_HUMAN	Beclin 1-associated autophagy-related key regulator	19270696	Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages.

Q9FVW3	Y1399_ARATH	Probable esterase At1g33990	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P27487	DPP4_HUMAN	Dipeptidyl peptidase 4	17287217	Caveolin-1 triggers T-cell activation via CD26 in association with CARMA1.

Q9D8Y7	TP8L2_MOUSE	Tumor necrosis factor alpha-induced protein 8-like protein 2	18455983	TIPE2, a negative regulator of innate and adaptive immunity that maintains immune homeostasis.

Q12272	TPT1_YEAST	tRNA 2'-phosphotransferase	9148937	A 2'-phosphotransferase implicated in tRNA splicing is essential in Saccharomyces cerevisiae.

P04920	B3A2_HUMAN	Anion exchange protein 2	3015590	Cloning and structural characterization of a human non-erythroid band 3-like protein.

Q19203	UNC98_CAEEL	Zinc finger protein unc-98	12808046	Caenorhabditis elegans UNC-98, a C2H2 Zn finger protein, is a novel partner of UNC-97/PINCH in muscle adhesion complexes.

Q7TQA6	T2R38_MOUSE	Taste receptor type 2 member 38	12734386	Evolutionary relationships of the Tas2r receptor gene families in mouse and human.

Q8MKJ4	OB57B_DROME	General odorant-binding protein 57b	12213773	Genome-wide analysis of the odorant-binding protein gene family in Drosophila melanogaster.

Q8IWE5	PKHM2_HUMAN	Pleckstrin homology domain-containing family M member 2	15905402	The intracellular fate of Salmonella depends on the recruitment of kinesin.

Q9SJU4	ALFC1_ARATH	Probable fructose-bisphosphate aldolase 1, chloroplastic	16461379	Protein profiling of plastoglobules in chloroplasts and chromoplasts. A surprising site for differential accumulation of metabolic enzymes.

O94388	VPS92_SCHPO	Vacuolar protein sorting-associated protein 9b	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9QWL7	K1C17_MOUSE	Keratin, type I cytoskeletal 17	16702408	Keratin 17 modulates hair follicle cycling in a TNFalpha-dependent fashion.

O23116	EIL3_ARATH	ETHYLENE INSENSITIVE 3-like 3 protein	15811366	Solution structure of the major DNA-binding domain of Arabidopsis thaliana ethylene-insensitive3-like3.

Q03776	PRP42_YEAST	U1 small nuclear ribonucleoprotein component PRP42	9630245	A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins.

Q9QYC3	BHA15_MOUSE	Class A basic helix-loop-helix protein 15	9073453	Mist1: a novel basic helix-loop-helix transcription factor exhibits a developmentally regulated expression pattern.

P0A8I8	RLMH_ECOLI	Ribosomal RNA large subunit methyltransferase H	18755835	YbeA is the m3Psi methyltransferase RlmH that targets nucleotide 1915 in 23S rRNA.

P38418	LOX2_ARATH	Lipoxygenase 2, chloroplastic	15028209	The Arabidopsis thaliana chloroplast proteome reveals pathway abundance and novel protein functions.

P62755	RS6_RAT	40S ribosomal protein S6	3277962	The primary structure of rat ribosomal protein S6.

O14417	MAD2_SCHPO	Mitotic spindle checkpoint component mad2	11909965	Fission yeast Mad3p is required for Mad2p to inhibit the anaphase- promoting complex and localizes to kinetochores in a Bub1p-, Bub3p-, and Mph1p-dependent manner.

P01149	MFAL1_YEAST	Mating factor alpha-1	6754095	Structure of a yeast pheromone gene (MF alpha): a putative alpha- factor precursor contains four tandem copies of mature alpha-factor.

P0A8L1	SYS_ECOLI	Seryl-tRNA synthetase	7537870	Seryl-tRNA synthetase from Escherichia coli: functional evidence for cross-dimer tRNA binding during aminoacylation.

Q9Y6A1	POMT1_HUMAN	Protein O-mannosyl-transferase 1	10366449	Identification of a human homolog of the Drosophila rotated abdomen gene (POMT1) encoding a putative protein O-mannosyl-transferase, and assignment to human chromosome 9q34.1.

Q8QZY3	DPPA3_MOUSE	Developmental pluripotency-associated protein 3	11900980	Identification of PGC7, a new gene expressed specifically in preimplantation embryos and germ cells.

P41743	KPCI_HUMAN	Protein kinase C iota type	8226978	Molecular cloning and characterization of PKC iota, an atypical isoform of protein kinase C derived from insulin-secreting cells.

Q9JI39	ABCBA_MOUSE	ATP-binding cassette sub-family B member 10, mitochondrial	10835348	ABC-me: a novel mitochondrial transporter induced by GATA-1 during erythroid differentiation.

P28700	RXRA_MOUSE	Retinoic acid receptor RXR-alpha	1312497	Characterization of three RXR genes that mediate the action of 9-cis retinoic acid.

Q9JJQ0	PIGB_MOUSE	GPI mannosyltransferase 3	8861954	PIG-B, a membrane protein of the endoplasmic reticulum with a large lumenal domain, is involved in transferring the third mannose of the GPI anchor.

P09759	EPHB1_RAT	Ephrin type-B receptor 1	2017163	Characterization of elk, a brain-specific receptor tyrosine kinase.

P40070	LSM4_YEAST	U6 snRNA-associated Sm-like protein LSm4	10369684	Sm and Sm-like proteins assemble in two related complexes of deep evolutionary origin.

Q9UKF7	PITC1_HUMAN	Cytoplasmic phosphatidylinositol transfer protein 1	10531358	Cloning and characterization of a novel human phosphatidylinositol transfer protein, rdgBbeta.

P56719	OX2R_RAT	Orexin receptor type 2	9491897	Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior.

P39060	COIA1_HUMAN	Collagen alpha-1(XVIII) chain	10942434	Collagen XVIII, containing an endogenous inhibitor of angiogenesis and tumor growth, plays a critical role in the maintenance of retinal structure and in neural tube closure.

P33997	ALPA_ECOLI	Prophage CP4-57 regulatory protein AlpA	7511582	Alp suppression of Lon: dependence on the slpA gene.

Q86Y01	DTX1_HUMAN	Protein deltex-1	17028573	Itch/AIP4 mediates Deltex degradation through the formation of K29- linked polyubiquitin chains.

O08792	COE2_MOUSE	Transcription factor COE2	9211912	Mmot1, a new helix-loop-helix transcription factor gene displaying a sharp expression boundary in the embryonic mouse brain.

Q12486	YOR31_YEAST	Putative uncharacterized hydrolase YOR131C	14562095	Global analysis of protein localization in budding yeast.

Q84LH8	PIF5_ARATH	Transcription factor PIF5	15486100	A novel molecular recognition motif necessary for targeting photoactivated phytochrome signaling to specific basic helix-loop- helix transcription factors.

Q05636	RRP45_YEAST	Exosome complex component RRP45	10465791	The yeast exosome and human PM-Scl are related complexes of 3'-->5' exonucleases.

Q8T0S6	HIPPO_DROME	Serine/threonine-protein kinase hippo	20159598	Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded.

Q866N2	MYOC_RABIT	Myocilin	12697062	Characterization of rabbit myocilin: implications for human myocilin glycosylation and signal peptide usage.

Q9PUK5	PAX8_XENLA	Paired box protein Pax-8	10491256	Synergism between Pax-8 and lim-1 in embryonic kidney development.

Q9P7F3	AMT3_SCHPO	Ammonium transporter 3	16999738	Ammonium transporter genes in the fission yeast Schizosaccharomyces pombe: role in ammonium uptake and a morphological transition.

P38427	TSL1_YEAST	Trehalose synthase complex regulatory subunit TSL1	9837904	Composition and functional analysis of the Saccharomyces cerevisiae trehalose synthase complex.

P90520	TOP2M_DICDI	DNA topoisomerase 2, mitochondrial	9177484	Cloning and characterization of the gene encoding a mitochondrially localized DNA topoisomerase II in Dictyostelium discoideum. Western blot analysis.

Q96PM5	ZN363_HUMAN	RING finger and CHY zinc finger domain-containing protein 1	15781263	A new human gene hNTKL-BP1 interacts with hPirh2.

O77459	KEN_DROME	Transcription factor Ken	14518006	The ken and barbie gene encoding a putative transcription factor with a BTB domain and three zinc finger motifs functions in terminalia development of Drosophila.

O94534	ALP14_SCHPO	Spindle pole body component alp14	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9FE25	MYB75_ARATH	Transcription factor MYB75	16463103	The MYB transcription factor superfamily of Arabidopsis: expression analysis and phylogenetic comparison with the rice MYB family.

O95936	EOMES_HUMAN	Eomesodermin homolog	17566017	The T-box transcription factor eomesodermin controls CD8 T cell activity and lymph node metastasis in human colorectal cancer.

Q03029	SPO19_YEAST	Sporulation-specific protein 19	11101837	The core meiotic transcriptome in budding yeasts.

P40146	ADCY8_RAT	Adenylate cyclase type 8	8163524	Type VIII adenylyl cyclase. A Ca2+/calmodulin-stimulated enzyme expressed in discrete regions of rat brain.

P0ADE8	YGFZ_ECOLI	tRNA-modifying protein ygfZ	15489424	Crystal structure of the YgfZ protein from Escherichia coli suggests a folate-dependent regulatory role in one-carbon metabolism.

P28356	HXD9_HUMAN	Homeobox protein Hox-D9	1756725	HOX4 genes encode transcription factors with potential auto- and cross-regulatory capacities.

Q9BZQ4	NMNA2_HUMAN	Nicotinamide mononucleotide adenylyltransferase 2	16118205	Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms.

Q8BJS4	SUN2_MOUSE	SUN domain-containing protein 2	19933576	Mammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processes.

Q9ZSD4	SY121_ARATH	Syntaxin-121	9915701	A tobacco syntaxin with a role in hormonal control of guard cell ion channels.

Q9NRL2	BAZ1A_HUMAN	Bromodomain adjacent to zinc finger domain protein 1A	10662543	A novel family of bromodomain genes.

P12683	HMDH1_YEAST	3-hydroxy-3-methylglutaryl-coenzyme A reductase 1	3526336	Saccharomyces cerevisiae contains two functional genes encoding 3- hydroxy-3-methylglutaryl-coenzyme A reductase.

Q05996	ZP2_HUMAN	Zona pellucida sperm-binding protein 2	8385033	Conservation of mammalian secondary sperm receptor genes enables the promoter of the human gene to function in mouse oocytes.

Q96MH2	HEXI2_HUMAN	Protein HEXIM2	15713661	Compensatory contributions of HEXIM1 and HEXIM2 in maintaining the balance of active and inactive positive transcription elongation factor b complexes for control of transcription.

Q9UR24	RHP26_SCHPO	DNA repair protein rhp26	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q06506	RRP9_YEAST	Ribosomal RNA-processing protein 9	11105764	Yeast Rrp9p is an evolutionarily conserved U3 snoRNP protein essential for early pre-rRNA processing cleavages and requires box C for its association.

O59708	YN4B_SCHPO	Uncharacterized protein C36.11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q91WF7	FIG4_MOUSE	Polyphosphoinositide phosphatase	17572665	Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J.

Q08920	NCBP2_YEAST	Nuclear cap-binding protein subunit 2	8811086	A yeast cap binding protein complex (yCBC) acts at an early step in pre-mRNA splicing.

Q9UIS9	MBD1_HUMAN	Methyl-CpG-binding domain protein 1	12665582	MCAF mediates MBD1-dependent transcriptional repression.

P39769	PHP_DROME	Polyhomeotic-proximal chromatin protein	12834867	Trl-GAGA directly interacts with lola like and both are part of the repressive complex of Polycomb group of genes.

O14548	COX7R_HUMAN	Cytochrome c oxidase subunit 7A-related protein, mitochondrial	9418891	Isolation of estrogen-responsive genes with a CpG island library.

Q08496	DIA2_YEAST	Protein DIA2	15620357	Pheromone-dependent destruction of the Tec1 transcription factor is required for MAP kinase signaling specificity in yeast.

P12956	XRCC6_HUMAN	X-ray repair cross-complementing protein 6	11493912	Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair.

P48381	RFX3_MOUSE	Transcription factor RFX3	19671664	RFX3 governs growth and beating efficiency of motile cilia in mouse and controls the expression of genes involved in human ciliopathies.

Q8R0W6	NFIP1_MOUSE	NEDD4 family-interacting protein 1	11042109	Identification of multiple proteins expressed in murine embryos as binding partners for the WW domains of the ubiquitin-protein ligase Nedd4.

O01840	PEPT3_CAEEL	Peptide transporter 3	10734106	A novel H(+)-coupled oligopeptide transporter (OPT3) from Caenorhabditis elegans with a predominant function as a H(+) channel and an exclusive expression in neurons.

Q12199	TIP41_YEAST	Type 2A phosphatase activator TIP41	14562095	Global analysis of protein localization in budding yeast.

Q9BV10	ALG12_HUMAN	Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase	11983712	Congenital disorders of glycosylation type Ig is defined by a deficiency in dolichyl-P-mannose:Man7GlcNAc2-PP-dolichyl mannosyltransferase.

P47927	AP2_ARATH	Floral homeotic protein APETALA 2	7919989	Control of Arabidopsis flower and seed development by the homeotic gene APETALA2.

P06983	HEM3_ECOLI	Porphobilinogen deaminase	3052434	Purification, crystallization and properties of porphobilinogen deaminase from a recombinant strain of Escherichia coli K12.

P39105	PLB1_YEAST	Lysophospholipase 1	10383953	Amino acid residues in the omega-minus region participate in cellular localization of yeast glycosylphosphatidylinositol-attached proteins.

P15364	AMAL_DROME	Protein amalgam	3141062	Characterization of amalgam: a member of the immunoglobulin superfamily from Drosophila.

Q8VCM2	NOXO1_MOUSE	NADPH oxidase organizer 1	12473664	Two novel proteins activate superoxide generation by the NADPH oxidase NOX1.

P55075	FGF8_HUMAN	Fibroblast growth factor 8	18596921	Decreased FGF8 signaling causes deficiency of gonadotropin-releasing hormone in humans and mice.

Q6NVF4	HELB_MOUSE	DNA helicase B	11557815	Molecular cloning of a cDNA encoding mouse DNA helicase B, which has homology to Escherichia coli RecD protein, and identification of a mutation in the DNA helicase B from tsFT848 temperature-sensitive DNA replication mutant cells.

Q91876	MCM7A_XENLA	DNA replication licensing factor mcm7-A	9214647	Licensing of DNA replication by a multi-protein complex of MCM/P1 proteins in Xenopus eggs.

Q9USP4	MUG1_SCHPO	Meiotically up-regulated gene 1 protein	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

O43805	SSNA1_HUMAN	Sjoegren syndrome nuclear autoantigen 1	9430706	NA14 is a novel nuclear autoantigen with a coiled-coil domain.

B6ZK77	IRL1B_DANRE	Interleukin-1 receptor accessory protein-like 1-B	18657618	Zebrafish orthologue of mental retardation protein IL1RAPL1 regulates presynaptic differentiation.

Q9Y237	PIN4_HUMAN	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4	12144781	The N-terminal basic domain of human parvulin hPar14 is responsible for the entry to the nucleus and high-affinity DNA-binding.

Q9GYF1	TNNI2_CAEEL	Troponin I 2	15743415	Tissue expression of four troponin I genes and their molecular interactions with two troponin C isoforms in Caenorhabditis elegans.

Q9BVA0	KTNB1_HUMAN	Katanin p80 WD40-containing subunit B1	9568719	Katanin, a microtubule-severing protein, is a novel AAA ATPase that targets to the centrosome using a WD40-containing subunit.

P84388	PLYB1_POLPI	Polybine-1	15572194	Structural and functional characterization of N-terminally blocked peptides isolated from the venom of the social wasp Polybia paulista.

Q9BDK6	AT1B4_PIG	Protein ATP1B4	14656723	Accumulation of beta (m), a structural member of X,K-ATPase beta- subunit family, in nuclear envelopes of perinatal myocytes.

O60307	MAST3_HUMAN	Microtubule-associated serine/threonine-protein kinase 3	15951562	Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases.

Q13426	XRCC4_HUMAN	DNA repair protein XRCC4	9242410	Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells.

P22336	RFA1_YEAST	Replication factor A protein 1	16678108	The structure of the yFACT Pob3-M domain, its interaction with the DNA replication factor RPA, and a potential role in nucleosome deposition.

Q05437	PRRX1_CHICK	Paired mesoderm homeobox protein 1	11036080	A set of Hox proteins interact with the Maf oncoprotein to inhibit its DNA binding, transactivation, and transforming activities.

P25559	DCC1_YEAST	Sister chromatid cohesion protein DCC1	11389843	Identification of RFC(Ctf18p, Ctf8p, Dcc1p): an alternative RFC complex required for sister chromatid cohesion in S. cerevisiae.

Q4JL84	MYB59_ARATH	Transcription factor MYB59	16531467	A subgroup of MYB transcription factor genes undergoes highly conserved alternative splicing in Arabidopsis and rice.

Q9PUK8	FZD7A_XENLA	Frizzled-7-A	16604063	Syndecan-4 regulates non-canonical Wnt signalling and is essential for convergent and extension movements in Xenopus embryos.

Q16653	MOG_HUMAN	Myelin-oligodendrocyte glycoprotein	8530032	The human myelin oligodendrocyte glycoprotein (MOG) gene: complete nucleotide sequence and structural characterization.

P97633	KC1A_RAT	Casein kinase I isoform alpha	8973207	Casein kinase I alpha and alpha L: alternative splicing-generated kinases exhibit different catalytic properties.

Q9NUB1	ACS2L_HUMAN	Acetyl-coenzyme A synthetase 2-like, mitochondrial	19535340	Crystal structures of human SIRT3 displaying substrate-induced conformational changes.

P37172	ACVR1_MOUSE	Activin receptor type-1	8388127	Cloning of a type I TGF-beta receptor and its effect on TGF-beta binding to the type II receptor.

Q10252	COQ2_SCHPO	Para-hydroxybenzoate--polyprenyltransferase, mitochondrial	11092853	Phenotypes of fission yeast defective in ubiquinone production due to disruption of the gene for p-hydroxybenzoate polyprenyl diphosphate transferase.

Q02733	IRC15_YEAST	Increased recombination centers protein 15	14562095	Global analysis of protein localization in budding yeast.

P01706	LV203_HUMAN	Ig lambda chain V-II region BOH	804002	The primary structure of a human lambda II chain.

O95183	VAMP5_HUMAN	Vesicle-associated membrane protein 5	9725904	A novel synaptobrevin/VAMP homologous protein (VAMP5) is increased during in vitro myogenesis and present in the plasma membrane.

Q5AX00	CUTI3_EMENI	Cutinase 3	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

Q07307	UAPA_EMENI	Uric acid-xanthine permease	20002879	Transport-dependent endocytosis and turnover of a uric acid-xanthine permease.

Q9LJN2	MRS23_ARATH	Magnesium transporter MRS2-3	19966073	A root-expressed magnesium transporter of the MRS2/MGT gene family in Arabidopsis thaliana allows for growth in low-Mg2+ environments.

O95045	UPP2_HUMAN	Uridine phosphorylase 2	12849978	Identification of a novel human uridine phosphorylase.

O09209	BXRA_AGRCO	Bombyxin-related peptide A	8673077	Bombyxin-related peptides: cDNA structure and expression in the brain of the hornworm Agrius convolvuli.

P58955	GR36A_DROME	Putative gustatory receptor 36a	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

O04532	FH8_ARATH	Formin-like protein 8	15923338	Cloning and functional characterization of a formin-like protein (AtFH8) from Arabidopsis.

P32451	BIOB_YEAST	Biotin synthase, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

Q14739	LBR_HUMAN	Lamin-B receptor	15882967	The mammalian heterochromatin protein 1 binds diverse nuclear proteins through a common motif that targets the chromoshadow domain.

O43293	DAPK3_HUMAN	Death-associated protein kinase 3	10356987	ZIP kinase identified as a novel myosin regulatory light chain kinase in HeLa cells.

P0C5Y7	TEN1_SCHPO	Protein ten1	17715303	Protection of telomeres by a conserved Stn1-Ten1 complex.

P07256	QCR1_YEAST	Cytochrome b-c1 complex subunit 1, mitochondrial	10873857	Structure at 2.3 A resolution of the cytochrome bc1 complex from the yeast Saccharomyces cerevisiae co-crystallized with an antibody Fv fragment.

P51652	AKC1H_RAT	Aldo-keto reductase family 1 member C18	8172618	Molecular cloning of cDNA for rat ovarian 20 alpha-hydroxysteroid dehydrogenase (HSD1).

P20348	JANA_DROME	Sex-regulated protein janus-A	2503707	Transcriptional and posttranscriptional regulation contributes to the sex-regulated expression of two sequence-related genes at the janus locus of Drosophila melanogaster.

Q9Y4K3	TRAF6_HUMAN	TNF receptor-associated factor 6	9915784	Association of the p75 neurotrophin receptor with TRAF6.

Q645N4	PAX3A_XENLA	Paired box protein Pax-3-A	15843410	Neural crest determination by co-activation of Pax3 and Zic1 genes in Xenopus ectoderm.

O22779	TRL13_ARATH	Thioredoxin-like 1-3, chloroplastic	19109414	A small family of chloroplast atypical thioredoxins.

Q08271	GAS4_YEAST	1,3-beta-glucanosyltransferase GAS4	17189486	GAS2 and GAS4, a pair of developmentally regulated genes required for spore wall assembly in Saccharomyces cerevisiae.

P09880	TRNL_YEAST	tRNA ligase	3277966	Structure and function of the yeast tRNA ligase gene.

Q9BUJ2	HNRL1_HUMAN	Heterogeneous nuclear ribonucleoprotein U-like protein 1	9733834	E1B-55kilodalton-associated protein: a cellular protein with RNA- binding activity implicated in nucleocytoplasmic transport of adenovirus and cellular mRNAs.

O00899	GAPA_DICDI	Ras GTPase-activating-like protein gapA	17517120	STATc is a key regulator of the transcriptional response to hyperosmotic shock.

Q03157	APLP1_MOUSE	Amyloid-like protein 1	1279693	Identification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid beta protein precursor.

Q9XXU9	VATC_CAEEL	V-type proton ATPase subunit C	9712884	Multiple genes for vacuolar-type ATPase proteolipids in Caenorhabditis elegans: a new gene, vha-3, has a distinct cell- specific distribution.

P25522	MNME_ECOLI	tRNA modification GTPase mnmE	1917835	Molecular cloning and sequence of the thdF gene, which is involved in thiophene and furan oxidation by Escherichia coli.

O04348	TPP1_ARATH	Thylakoidal processing peptidase 1, chloroplastic	9422718	Characterization of a cDNA encoding the thylakoidal processing peptidase from Arabidopsis thaliana. Implications for the origin and catalytic mechanism of the enzyme.

P51802	CLCKB_RAT	Chloride channel protein ClC-Kb	8021279	Two isoforms of a chloride channel predominantly expressed in thick ascending limb of Henle's loop and collecting ducts of rat kidney.

Q92520	FAM3C_HUMAN	Protein FAM3C	12160727	Cloning, expression, and initial characterization of a novel cytokine-like gene family.

Q8TDX9	PK1L1_HUMAN	Polycystic kidney disease protein 1-like 1	11863367	The sequence, expression, and chromosomal localization of a novel polycystic kidney disease 1-like gene, PKD1L1, in human.

Q12255	NYV1_YEAST	Vacuolar v-SNARE NYV1	11823419	The Vtc proteins in vacuole fusion: coupling NSF activity to V(0) trans-complex formation.

O14097	YERE_SCHPO	WW domain-containing protein C2F3.14c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P47181	YJ9S_YEAST	Uncharacterized protein YJR154W	14562095	Global analysis of protein localization in budding yeast.

P42844	ZIM17_YEAST	Mitochondrial protein import protein ZIM17	15719019	Maintenance of structure and function of mitochondrial Hsp70 chaperones requires the chaperone Hep1.

O43808	PM34_HUMAN	Peroxisomal membrane protein PMP34	10704444	PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis.

Q9FMF5	RPT3_ARATH	Root phototropism protein 3	10542152	Arabidopsis NPH3: a NPH1 photoreceptor-interacting protein essential for phototropism.

Q9VWV9	PORCN_DROME	Protein-cysteine N-palmitoyltransferase porcupine	11821428	Drosophila segment polarity gene product porcupine stimulates the posttranslational N-glycosylation of wingless in the endoplasmic reticulum.

Q86WG5	MTMRD_HUMAN	Myotubularin-related protein 13	15998640	The phosphoinositide-3-phosphatase MTMR2 associates with MTMR13, a membrane-associated pseudophosphatase also mutated in type 4B Charcot- Marie-Tooth disease.

Q09013	DMPK_HUMAN	Myotonin-protein kinase	10913253	Myotonic dystrophy protein kinase domains mediate localization, oligomerization, novel catalytic activity, and autoinhibition.

Q80UA9	INSI2_RAT	Insulin-induced gene 2 protein	12624180	Liver-specific mRNA for Insig-2 down-regulated by insulin: implications for fatty acid synthesis.

Q16581	C3AR_HUMAN	C3a anaphylatoxin chemotactic receptor	8702752	Molecular cloning and characterization of the human anaphylatoxin C3a receptor.

P0AFL6	PPX_ECOLI	Exopolyphosphatase	8380170	An exopolyphosphatase of Escherichia coli. The enzyme and its ppx gene in a polyphosphate operon.

P40343	VPS27_YEAST	Vacuolar protein sorting-associated protein 27	8649377	The newly identified yeast GRD genes are required for retention of late-Golgi membrane proteins.

Q96PN7	TREF1_HUMAN	Transcriptional-regulating factor 1	11349124	A novel zinc finger protein TReP-132 interacts with CBP/p300 to regulate human CYP11A1 gene expression.

Q5W7F2	AGD3_ARATH	ADP-ribosylation factor GTPase-activating protein AGD3	15743878	VAN3 ARF-GAP-mediated vesicle transport is involved in leaf vascular network formation.

O01427	AIR2_CAEEL	Aurora/IPL1-related protein kinase 2	11940606	The aurora kinase AIR-2 functions in the release of chromosome cohesion in Caenorhabditis elegans meiosis.

Q9W7E7	SMAD5_DANRE	Mothers against decapentaplegic homolog 5	10207140	The smad5 mutation somitabun blocks Bmp2b signaling during early dorsoventral patterning of the zebrafish embryo.

P43605	ECO1_YEAST	N-acetyltransferase ECO1	15020404	Chl1p, a DNA helicase-like protein in budding yeast, functions in sister-chromatid cohesion.

Q8VHE6	DYH5_MOUSE	Dynein heavy chain 5, axonemal	11912187	Loss of function of axonemal dynein Mdnah5 causes primary ciliary dyskinesia and hydrocephalus.

Q9ES39	NDE1_RAT	Nuclear distribution protein nudE homolog 1	10940388	Direct association of LIS1, the lissencephaly gene product, with a mammalian homologue of a fungal nuclear distribution protein, rNUDE.

P75876	RLMI_ECOLI	Ribosomal RNA large subunit methyltransferase I	18786544	YccW is the m5C methyltransferase specific for 23S rRNA nucleotide 1962.

P47165	XPT1_YEAST	Xanthine phosphoribosyltransferase 1	14562095	Global analysis of protein localization in budding yeast.

P29419	ATP5I_RAT	ATP synthase subunit e, mitochondrial	1463732	Complete amino acid sequence of subunit e of rat liver mitochondrial H(+)-ATP synthase.

Q8STE5	CED12_CAEEL	Cell death abnormality protein 12	11595183	CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration.

Q8K4J0	DCR1C_MOUSE	Protein artemis	12615897	Defective DNA repair and increased genomic instability in Artemis- deficient murine cells.

O35116	CTND2_RAT	Catenin delta-2	10896674	A novel multiple PSD-95/Dlg-A/ZO-1 protein interacting with neural plakophilin-related armadillo repeat protein/delta-catenin and p0071.

Q9SXZ2	FT_ARATH	Protein FLOWERING LOCUS T	10583961	Activation tagging of the floral inducer FT.

P32783	MCES_YEAST	mRNA cap guanine-N7 methyltransferase	7623811	Yeast mRNA cap methyltransferase is a 50-kilodalton protein encoded by an essential gene.

O13652	SFI1_SCHPO	Protein sfi1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P39981	AVT2_YEAST	Vacuolar amino acid transporter 2	11274162	A family of yeast proteins mediating bidirectional vacuolar amino acid transport.

Q9UQ80	PA2G4_HUMAN	Proliferation-associated protein 2G4	11325528	Regulation of the ErbB3 binding protein Ebp1 by protein kinase C.

O54905	B3GT2_MOUSE	Beta-1,3-galactosyltransferase 2	9417047	Genomic cloning and expression of three murine UDP-galactose: beta-N- acetylglucosamine beta1,3-galactosyltransferase genes.

O80860	FTSH2_ARATH	ATP-dependent zinc metalloprotease FTSH 2, chloroplastic	11717304	A critical role for the Var2 FtsH homologue of Arabidopsis thaliana in the photosystem II repair cycle in vivo.

Q8NEC5	CTSR1_HUMAN	Cation channel sperm-associated protein 1	16740636	Association of Catsper1 or -2 with Ca(v)3.3 leads to suppression of T-type calcium channel activity.

P15385	KCNA4_RAT	Potassium voltage-gated channel subfamily A member 4	2384173	Molecular cloning and functional expression of a potassium channel cDNA isolated from a rat cardiac library.

Q8UVQ4	KAISO_XENLA	Transcriptional regulator Kaiso	15543138	Non-canonical Wnt signals are modulated by the Kaiso transcriptional repressor and p120-catenin.

P29401	TKT_HUMAN	Transketolase	8419340	Cloning of human transketolase cDNAs and comparison of the nucleotide sequence of the coding region in Wernicke-Korsakoff and non-Wernicke- Korsakoff individuals.

Q2M3C7	SPKAP_HUMAN	A-kinase anchor protein SPHKAP	12080051	Cloning and characterization of a protein kinase A anchoring protein (AKAP)-related protein that interacts with and regulates sphingosine kinase 1 activity.

Q24039	BRO_DROME	Protein brother	8622696	Drosophila homologs of the proto-oncogene product PEBP2/CBF beta regulate the DNA-binding properties of Runt.

O96160	YPF14_PLAF7	Uncharacterized protein PFB0315w	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

Q969V5	MUL1_HUMAN	Mitochondrial ubiquitin ligase activator of NFKB 1	18213395	Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling.

Q9P7V3	TSN1_SCHPO	Translin-1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9LXC9	IPYR1_ARATH	Soluble inorganic pyrophosphatase 1, chloroplastic	16313235	A novel subfamily of monomeric inorganic pyrophosphatases in photosynthetic eukaryotes.

Q37001	1A15_ARATH	1-aminocyclopropane-1-carboxylate synthase 5	15118728	Regulation of ethylene gas biosynthesis by the Arabidopsis ETO1 protein.

Q04637	IF4G1_HUMAN	Eukaryotic translation initiation factor 4 gamma 1	10970864	Multiple portions of poly(A)-binding protein stimulate translation in vivo.

Q9VVN4	ATRIP_DROME	ATR-interacting protein mus304	10733527	mus304 encodes a novel DNA damage checkpoint protein required during Drosophila development.

Q9R141	S22A4_RAT	Solute carrier family 22 member 4	10825452	Structural and functional characteristics and tissue distribution pattern of OCTN1, an organic cation transporter, cloned from placenta.

Q9UKY3	EST4_HUMAN	Putative inactive carboxylesterase 4	10452915	Human carboxylesterases in term placentae: enzymatic characterization, molecular cloning and evidence for the existence of multiple forms.

P16083	NQO2_HUMAN	Ribosyldihydronicotinamide dehydrogenase [quinone]	1691923	Nucleotide and deduced amino acid sequence of a human cDNA (NQO2) corresponding to a second member of the NAD(P)H:quinone oxidoreductase gene family. Extensive polymorphism at the NQO2 gene locus on chromosome 6.

Q04724	TLE1_HUMAN	Transducin-like enhancer protein 1	1303260	Human homologs of a Drosophila enhancer of split gene product define a novel family of nuclear proteins.

P87061	TEA1_SCHPO	Tip elongation aberrant protein 1	15936270	Wsh3/Tea4 is a novel cell-end factor essential for bipolar distribution of Tea1 and protects cell polarity under environmental stress in S. pombe.

Q9Y274	SIA10_HUMAN	Type 2 lactosamine alpha-2,3-sialyltransferase	10206952	Molecular cloning of a novel alpha2,3-sialyltransferase (ST3Gal VI) that sialylates type II lactosamine structures on glycoproteins and glycolipids.

P13945	ADRB3_HUMAN	Beta-3 adrenergic receptor	2570461	Molecular characterization of the human beta 3-adrenergic receptor.

P46784	RS10B_YEAST	40S ribosomal protein S10-B	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

O75446	SAP30_HUMAN	Histone deacetylase complex subunit SAP30	9651585	SAP30, a novel protein conserved between human and yeast, is a component of a histone deacetylase complex.

O74779	MU164_SCHPO	Microtubule-associated protein mug164	15797925	The nuclear rim protein Amo1 is required for proper microtubule cytoskeleton organisation in fission yeast.

Q9QZQ5	NOV_RAT	Protein NOV homolog	10570975	Nephroblastoma overexpressed gene (NOV) codes for a growth factor that induces protein tyrosine phosphorylation.

Q91876	MCM7A_XENLA	DNA replication licensing factor mcm7-A	9512418	Developmental regulation of MCM replication factors in Xenopus laevis.

Q941L0	CESA3_ARATH	Cellulose synthase A catalytic subunit 3 [UDP-forming]	12068120	Functional analysis of the cellulose synthase genes CesA1, CesA2, and CesA3 in Arabidopsis.

O94307	PFD5_SCHPO	Probable prefoldin subunit 5	11683500	Bob1, a Gim5/MM-1/Pfd5 homolog, interacts with the MAP kinase kinase byr1 to regulate sexual differentiation in the fission yeast, Schizosaccharomyces pombe.

O00327	BMAL1_HUMAN	Aryl hydrocarbon receptor nuclear translocator-like protein 1	9616112	Role of the CLOCK protein in the mammalian circadian mechanism.

Q9P6M3	MIS14_SCHPO	Kinetochore protein mis14	15369671	Mis16 and Mis18 are required for CENP-A loading and histone deacetylation at centromeres.

O94620	CWF17_SCHPO	Cell cycle control protein cwf17	11884590	Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

P23246	SFPQ_HUMAN	Splicing factor, proline- and glutamine-rich	9848648	The snRNP-free U1A (SF-A) complex(es): identification of the largest subunit as PSF, the polypyrimidine-tract binding protein-associated splicing factor.

P51830	ADCY9_MOUSE	Adenylate cyclase type 9	8662814	Identification and characterization of a widely expressed form of adenylyl cyclase.

Q80W22	THNS2_MOUSE	Threonine synthase-like 2	17034760	A threonine synthase homolog from a mammalian genome.

O14990	IPP4_HUMAN	Putative type-1 protein phosphatase inhibitor 4	11076525	Identification and characterization of a novel protein inhibitor of type 1 protein phosphatase.

P53228	TAL2_YEAST	Transaldolase NQM1	18831051	The crystal structure and identification of NQM1/YGR043C, a transaldolase from Saccharomyces cerevisiae.

O22264	MYB12_ARATH	Transcription factor MYB12	15923334	The Arabidopsis transcription factor MYB12 is a flavonol-specific regulator of phenylpropanoid biosynthesis.

P0AEC5	BARA_ECOLI	Signal transduction histidine-protein kinase BarA	11022030	Identification of UvrY as the cognate response regulator for the BarA sensor kinase in Escherichia coli.

Q62915	CSKP_RAT	Peripheral plasma membrane protein CASK	12040031	CASK participates in alternative tripartite complexes in which Mint 1 competes for binding with Caskin 1, a novel CASK-binding protein.

Q8BUX5	RHBG_MOUSE	Ammonium transporter Rh type B	12388412	Localization of the ammonium transporter proteins RhBG and RhCG in mouse kidney.

Q9UQ84	EXO1_HUMAN	Exonuclease 1	10364235	Human exonuclease 1 functionally complements its yeast homologues in DNA recombination, RNA primer removal, and mutation avoidance.

O00294	TULP1_HUMAN	Tubby-related protein 1	19837063	Identification of tubby and tubby-like protein 1 as eat-me signals by phage display.

Q9LF50	MEX1_ARATH	Maltose excess protein 1, chloroplastic	14704427	A previously unknown maltose transporter essential for starch degradation in leaves.

Q9JM05	PIAS4_MOUSE	E3 SUMO-protein ligase PIAS4	10854042	Cloning and analysis of a murine Pias family member, Pias-gamma, in developing skin and neurons.

Q949Y3	PPA26_ARATH	Bifunctional purple acid phosphatase 26	15215502	Isolation of intact vacuoles and proteomic analysis of tonoplast from suspension-cultured cells of Arabidopsis thaliana.

Q93ZR6	WSD1_ARATH	O-acyltransferase WSD1	18621978	Identification of the wax ester synthase/acyl-coenzyme A: diacylglycerol acyltransferase WSD1 required for stem wax ester biosynthesis in Arabidopsis.

Q60520	SIN3A_MOUSE	Paired amphipathic helix protein Sin3a	11390640	Pf1, a novel PHD zinc finger protein that links the TLE corepressor to the mSin3A-histone deacetylase complex.

P58743	S26A5_HUMAN	Prestin	12719379	Prestin, a cochlear motor protein, is defective in non-syndromic hearing loss.

P34219	TOD6_YEAST	Transcriptional regulatory protein TOD6	14562095	Global analysis of protein localization in budding yeast.

Q13183	S13A2_HUMAN	Solute carrier family 13 member 2	8967342	Molecular cloning and functional expression of a sodium-dicarboxylate cotransporter from human kidney.

Q0QF01	DHSA_PIG	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	15989954	Crystal structure of mitochondrial respiratory membrane protein complex II.

P50464	UNC97_CAEEL	LIM domain-containing protein unc-97	9885243	A conserved LIM protein that affects muscular adherens junction integrity and mechanosensory function in Caenorhabditis elegans.

Q94A82	NUD19_ARATH	Nudix hydrolase 19, chloroplastic	18815383	Molecular characterization of organelle-type Nudix hydrolases in Arabidopsis.

O95754	SEM4F_HUMAN	Semaphorin-4F	10051670	Cloning, expression, and genetic mapping of Sema W, a member of the semaphorin family.

P10644	KAP0_HUMAN	cAMP-dependent protein kinase type I-alpha regulatory subunit	15655353	The second subunit of the replication factor C complex (RFC40) and the regulatory subunit (RIalpha) of protein kinase A form a protein complex promoting cell survival.

Q99704	DOK1_HUMAN	Docking protein 1	9008160	p62(dok): a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells.

Q08379	GOGA2_HUMAN	Golgin subfamily A member 2	8315394	Molecular characterization of two human autoantigens: unique cDNAs encoding 95- and 160-kD proteins of a putative family in the Golgi complex.

P54100	VAV_RAT	Proto-oncogene vav	10395673	Tyrosine phosphorylation of Vav stimulates IL-6 production in mast cells by a Rac/c-Jun N-terminal kinase-dependent pathway.

P83582	FER_SOLNI	Ferredoxin	12620316	Large differences in amino acid sequences among ferredoxins from several species of genus Solanum.

P19524	MYO2_YEAST	Myosin-2	11285273	A role for actin, Cdc1p, and Myo2p in the inheritance of late Golgi elements in Saccharomyces cerevisiae.

Q8C7E9	CSTFT_MOUSE	Cleavage stimulation factor subunit 2 tau variant	11113135	The gene for a variant form of the polyadenylation protein CstF-64 is on chromosome 19 and is expressed in pachytene spermatocytes in mice.

P21589	5NTD_HUMAN	5'-nucleotidase	2129526	Primary structure of human placental 5'-nucleotidase and identification of the glycolipid anchor in the mature form.

Q03833	GIS1_YEAST	Transcriptional activator/repressor GIS1	10628841	Yeast genes GIS1-4: multicopy suppressors of the Gal- phenotype of snf1 mig1 srb8/10/11 cells.

Q14BB9	MA6D1_MOUSE	MAP6 domain-containing protein 1	16837464	STOP-like protein 21 is a novel member of the STOP family, revealing a Golgi localization of STOP proteins.

P07360	CO8G_HUMAN	Complement component C8 gamma chain	8172891	Genomic structure of the human complement protein C8 gamma: homology to the lipocalin gene family.

P13609	SRGN_MOUSE	Serglycin	15231821	Serglycin is essential for maturation of mast cell secretory granule.

Q9JHZ9	S38A3_RAT	Sodium-coupled neutral amino acid transporter 3	10823827	Primary structure, genomic organization, and functional and electrogenic characteristics of human system N 1, a Na+- and H+- coupled glutamine transporter.

Q9M9T4	PKS2_ARATH	Protein PHYTOCHROME KINASE SUBSTRATE 2	16777956	PHYTOCHROME KINASE SUBSTRATE 1 is a phototropin 1 binding protein required for phototropism.

O75223	GGCT_HUMAN	Gamma-glutamylcyclotransferase	18515354	The identification and structural characterization of C7orf24 as gamma-glutamyl cyclotransferase: an essential enzyme in the gamma- glutamyl cycle.

Q7G8V2	ARR15_ARATH	Two-component response regulator ARR15	11115887	Characterization of the response of the Arabidopsis response regulator gene family to cytokinin.

P19524	MYO2_YEAST	Myosin-2	10984058	Myosin V orientates the mitotic spindle in yeast.

P01574	IFNB_HUMAN	Interferon beta	2414376	On the relationship between human interferon alpha 1 and beta 1 genes.

P35590	TIE1_HUMAN	Tyrosine-protein kinase receptor Tie-1	1312667	A novel endothelial cell surface receptor tyrosine kinase with extracellular epidermal growth factor homology domains.

P84821	LEC_LITSE	Lectin 80 kDa subunit	15919156	Purification and characterization of a lectin from the white shrimp Litopenaeus setiferus (Crustacea decapoda) hemolymph.

Q9NYW6	TA2R3_HUMAN	Taste receptor type 2 member 3	10761934	A novel family of mammalian taste receptors.

Q94BR4	PR19A_ARATH	Pre-mRNA-processing factor 19 homolog 1	19629177	Two Prp19-like U-box proteins in the MOS4-associated complex play redundant roles in plant innate immunity.

P53865	CNM67_YEAST	Chaotic nuclear migration protein 67	9571234	Saccharomyces cerevisiae cells with defective spindle pole body outer plaques accomplish nuclear migration via half-bridge-organized microtubules.

Q86L04	TRAP1_DICDI	TNF receptor-associated protein 1 homolog, mitochondrial	15652353	Changes in spatial and temporal localization of Dictyostelium homologues of TRAP1 and GRP94 revealed by immunoelectron microscopy.

Q99NF1	BCDO2_MOUSE	Beta,beta-carotene 9',10'-oxygenase	11278918	Identification and characterization of a mammalian enzyme catalyzing the asymmetric oxidative cleavage of provitamin A.

P23767	GAT1A_XENLA	GATA-binding factor 1-A	11493549	Primitive erythropoiesis in the Xenopus embryo: the synergistic role of LMO-2, SCL and GATA-binding proteins.

P47120	DOHH_YEAST	Deoxyhypusine hydroxylase	16371467	Molecular cloning, expression, and structural prediction of deoxyhypusine hydroxylase: a HEAT-repeat-containing metalloenzyme.

Q9LU36	4CL4_ARATH	4-coumarate--CoA ligase 4	14769935	The 4-coumarate:CoA ligase gene family in Arabidopsis thaliana comprises one rare, sinapate-activating and three commonly occurring isoenzymes.

P20591	MX1_HUMAN	Interferon-induced GTP-binding protein Mx1	2154602	Cloning and sequence analyses of cDNAs for interferon- and virus- induced human Mx proteins reveal that they contain putative guanine nucleotide-binding sites: functional study of the corresponding gene promoter.

Q15139	KPCD1_HUMAN	Serine/threonine-protein kinase D1	12893243	Centaurin-alpha(1) associates with and is phosphorylated by isoforms of protein kinase C.

P59267	ZDHC2_MOUSE	Palmitoyltransferase ZDHHC2	15603741	Identification of PSD-95 palmitoylating enzymes.

Q9NRM7	LATS2_HUMAN	Serine/threonine-protein kinase LATS2	15131260	The LATS2/KPM tumor suppressor is a negative regulator of the androgen receptor.

P38919	IF4A3_HUMAN	Eukaryotic initiation factor 4A-III	14730019	eIF4A3 is a novel component of the exon junction complex.

Q9NYU2	UGGG1_HUMAN	UDP-glucose:glycoprotein glucosyltransferase 1	10694380	Two homologues encoding human UDP-glucose:glycoprotein glucosyltransferase differ in mRNA expression and enzymatic activity.

Q8N130	NPT2C_HUMAN	Sodium-dependent phosphate transport protein 2C	16358214	SLC34A3 mutations in patients with hereditary hypophosphatemic rickets with hypercalciuria predict a key role for the sodium- phosphate cotransporter NaPi-IIc in maintaining phosphate homeostasis.

Q9CXK4	R1AP1_MOUSE	RAG1-activating protein 1	8630032	Molecular cloning and characterization of a novel stromal cell- derived cDNA encoding a protein that facilitates gene activation of recombination activating gene (RAG)-1 in human lymphoid progenitors.

Q9BUI4	RPC3_HUMAN	DNA-directed RNA polymerase III subunit RPC3	19609254	RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate.

P40583	YPS6_YEAST	Aspartic proteinase yapsin-6	16087741	Yapsins are a family of aspartyl proteases required for cell wall integrity in Saccharomyces cerevisiae.

P36046	MIA40_YEAST	Mitochondrial intermembrane space import and assembly protein 40	15364952	Identification of Tim40 that mediates protein sorting to the mitochondrial intermembrane space.

Q9UW14	PACC_CANAL	pH-response transcription factor pacC/RIM101	10629054	RIM101-dependent and -independent pathways govern pH responses in Candida albicans.

Q969F8	KISSR_HUMAN	KiSS-1 receptor	11387329	AXOR12, a novel human G protein-coupled receptor, activated by the peptide KiSS-1.

P29590	PML_HUMAN	Probable transcription factor PML	12006491	Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence.

Q9SUE3	CRF4_ARATH	Ethylene-responsive transcription factor CRF4	16832061	A subset of Arabidopsis AP2 transcription factors mediates cytokinin responses in concert with a two-component pathway.

Q9EQU3	TLR9_MOUSE	Toll-like receptor 9	17452530	The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling.

Q03063	DIG1_YEAST	Down-regulator of invasive growth 1	10825185	Two regulators of Ste12p inhibit pheromone-responsive transcription by separate mechanisms.

Q8AXB3	VGFR4_DANRE	Vascular endothelial growth factor receptor kdr-like	12194822	Analysis of a zebrafish VEGF receptor mutant reveals specific disruption of angiogenesis.

P09208	INSR_DROME	Insulin-like receptor	7628438	The Drosophila insulin receptor homolog: a gene essential for embryonic development encodes two receptor isoforms with different signaling potential.

Q93052	LPP_HUMAN	Lipoma-preferred partner	15649318	The tumor suppressor Scrib interacts with the zyxin-related protein LPP, which shuttles between cell adhesion sites and the nucleus.

Q07011	TNR9_HUMAN	Tumor necrosis factor receptor superfamily member 9	8262389	A receptor induced by lymphocyte activation (ILA): a new member of the human nerve-growth-factor/tumor-necrosis-factor receptor family.

Q9US52	BQT2_SCHPO	Telomere bouquet protein 2	16615890	Meiotic proteins bqt1 and bqt2 tether telomeres to form the bouquet arrangement of chromosomes.

Q6IEG0	SNR48_HUMAN	U11/U12 small nuclear ribonucleoprotein 48 kDa protein	15146077	The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome.

P22059	OSBP1_HUMAN	Oxysterol-binding protein 1	1970801	cDNA cloning of human oxysterol-binding protein and localization of the gene to human chromosome 11 and mouse chromosome 19.

Q9UTI5	VPS29_SCHPO	Vacuolar protein sorting-associated protein 29	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q99873	ANM1_HUMAN	Protein arginine N-methyltransferase 1	9545638	Identification and characterization of two putative human arginine methyltransferases (HRMT1L1 and HRMT1L2).

Q10078	PPK13_SCHPO	Serine/threonine-protein kinase ppk13	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P53239	COX18_YEAST	Mitochondrial inner membrane protein COX18	11950926	Cox18p is required for export of the mitochondrially encoded Saccharomyces cerevisiae Cox2p C-tail and interacts with Pnt1p and Mss2p in the inner membrane.

P33412	ECT1_YEAST	Ethanolamine-phosphate cytidylyltransferase	8982874	Isolation and characterization of ECT1 gene encoding CTP: phosphoethanolamine cytidylyltransferase of Saccharomyces cerevisiae.

Q9LD28	H2A6_ARATH	Histone H2A.6	16751347	Constitutive expression exposes functional redundancy between the Arabidopsis histone H2A gene HTA1 and other H2A gene family members.

P39976	DLD3_YEAST	D-lactate dehydrogenase [cytochrome] 3	10509019	Signalling between mitochondria and the nucleus regulates the expression of a new D-lactate dehydrogenase activity in yeast.

Q01766	HAL1_YEAST	Halotolerance protein HAL1	1505513	A novel and conserved salt-induced protein is an important determinant of salt tolerance in yeast.

P50528	PLO1_SCHPO	Serine/threonine-protein kinase plo1	12615979	Polo boxes form a single functional domain that mediates interactions with multiple proteins in fission yeast polo kinase.

O15211	RGL2_HUMAN	Ral guanine nucleotide dissociation stimulator-like 2	8976381	Isolation and mapping of RAB2L, a human cDNA that encodes a protein homologous to RalGDS.

P33775	PMT1_YEAST	Dolichyl-phosphate-mannose--protein mannosyltransferase 1	8367478	PMT1, the gene for a key enzyme of protein O-glycosylation in Saccharomyces cerevisiae.

P40559	INP51_YEAST	Inositol-1,4,5-trisphosphate 5-phosphatase 1	17452534	PtdIns(4,5)P2 turnover is required for multiple stages during clathrin-and actin-dependent endocytic internalization.

O60068	ISD11_SCHPO	Protein isd11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P32486	KRE6_YEAST	Beta-glucan synthesis-associated protein KRE6	17893149	KEG1/YFR042w encodes a novel Kre6-binding endoplasmic reticulum membrane protein responsible for beta-1,6-glucan synthesis in Saccharomyces cerevisiae.

P18409	MDM10_YEAST	Mitochondrial distribution and morphology protein 10	17410204	The morphology proteins Mdm12/Mmm1 function in the major beta-barrel assembly pathway of mitochondria.

P07280	RS19A_YEAST	40S ribosomal protein S19-A	6814480	Isolation of seventeen proteins and amino-terminal amino acid sequences of eight proteins from cytoplasmic ribosomes of yeast.

P61587	RND3_HUMAN	Rho-related GTP-binding protein RhoE	8649376	Identification of a novel human Rho protein with unusual properties: GTPase deficiency and in vivo farnesylation.

P53150	LIF1_YEAST	Ligase-interacting factor 1	9670033	Saccharomyces cerevisiae LIF1: a function involved in DNA double- strand break repair related to mammalian XRCC4.

P33204	ARPC4_YEAST	Actin-related protein 2/3 complex subunit 4	9210376	The complex containing actin-related proteins Arp2 and Arp3 is required for the motility and integrity of yeast actin patches.

Q61625	GRID2_MOUSE	Glutamate receptor delta-2 subunit	12372286	A novel protein complex linking the delta 2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice.

Q9SMR4	RBH1C_ARATH	Ras-related protein RABH1C	18182439	Localization and domain characterization of Arabidopsis golgin candidates.

P07237	PDIA1_HUMAN	Protein disulfide-isomerase	3034602	Molecular cloning of the beta-subunit of human prolyl 4-hydroxylase. This subunit and protein disulphide isomerase are products of the same gene.

P39933	TF3A_YEAST	Transcription factor IIIA	1570325	Genes encoding transcription factor IIIA and the RNA polymerase common subunit RPB6 are divergently transcribed in Saccharomyces cerevisiae.

P32909	SMY2_YEAST	Protein SMY2	14562095	Global analysis of protein localization in budding yeast.

O94532	FOR3_SCHPO	Formin-3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P55852	SUMO1_ARATH	Small ubiquitin-related modifier 1	12482876	The small ubiquitin-like modifier (SUMO) protein modification system in Arabidopsis. Accumulation of SUMO1 and -2 conjugates is increased by stress.

P74873	SPTP_SALTY	Secreted effector protein sptP	11163217	Modulation of host signaling by a bacterial mimic: structure of the Salmonella effector SptP bound to Rac1.

P09923	PPBI_HUMAN	Intestinal-type alkaline phosphatase	2841341	Sequence and characterization of the human intestinal alkaline phosphatase gene.

Q61955	KLK8_MOUSE	Kallikrein-8	10421059	Effect of 12-O-tetradecanoyl-phorbol ester and incisional wounding on neuropsin mRNA and its protein expression in murine skin.

Q9UTN3	CID14_SCHPO	Poly(A) RNA polymerase cid14	17512405	RNAi-dependent and -independent RNA turnover mechanisms contribute to heterochromatic gene silencing.

O14960	LECT2_HUMAN	Leukocyte cell-derived chemotaxin-2	8877413	Purification and primary amino acid sequence of a novel neutrophil chemotactic factor LECT2.

O95613	PCNT_HUMAN	Pericentrin	18955030	DISC1-kendrin interaction is involved in centrosomal microtubule network formation.

Q23405	HIM14_CAEEL	MutS protein homolog him-14	10545458	Crossing over during Caenorhabditis elegans meiosis requires a conserved MutS-based pathway that is partially dispensable in budding yeast.

Q9V969	GR57A_DROME	Putative gustatory receptor 57a	10710312	Candidate taste receptors in Drosophila.

O43854	EDIL3_HUMAN	EGF-like repeat and discoidin I-like domain-containing protein 3	9420328	Cloning and characterization of developmental endothelial locus-1: an embryonic endothelial cell protein that binds the alphavbeta3 integrin receptor.

Q9FIZ7	OPLA_ARATH	5-oxoprolinase	18768907	A gamma-glutamyl transpeptidase-independent pathway of glutathione catabolism to glutamate via 5-oxoproline in Arabidopsis.

Q9JL35	HMGN5_MOUSE	High mobility group nucleosome-binding domain-containing protein 5	10692437	NBP-45, a novel nucleosomal binding protein with a tissue-specific and developmentally regulated expression.

P83335	TLP2_PRUPE	Thaumatin-like protein 2	11847241	Ethylene-responsive genes are differentially regulated during abscission, organ senescence and wounding in peach (Prunus persica).

Q9SK92	ATL15_ARATH	E3 ubiquitin-protein ligase ATL15	15644464	Functional analysis of the RING-type ubiquitin ligase family of Arabidopsis.

O94901	SUN1_HUMAN	SUN domain-containing protein 1	18396275	Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness.

P09238	MMP10_HUMAN	Stromelysin-2	2844164	The collagenase gene family in humans consists of at least four members.

P17794	VIRB4_AGRT5	Protein virB4	2233252	Characterization of the virB operon of an Agrobacterium tumefaciens Ti plasmid: nucleotide sequence and protein analysis.

P87305	CHAC_SCHPO	Cation transport regulator-like protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O42954	MBX1_SCHPO	MADS-box transcription factor 1	15509866	Fkh2p and Sep1p regulate mitotic gene transcription in fission yeast.

Q8IYB3	SRRM1_HUMAN	Serine/arginine repetitive matrix protein 1	9531537	A coactivator of pre-mRNA splicing.

Q9GZS9	CHST5_HUMAN	Carbohydrate sulfotransferase 5	12855678	Golgi localization of carbohydrate sulfotransferases is a determinant of L-selectin ligand biosynthesis.

P09557	DICB_ECOLI	Division inhibition protein dicB	3041373	Identification and sequence of gene dicB: translation of the division inhibitor from an in-phase internal start.

O60566	BUB1B_HUMAN	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta	9660858	The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase.

Q9FLB6	PR1B3_ARATH	PRA1 family protein B3	18583532	The PRA1 gene family in Arabidopsis.

P28159	SUH_DROME	Suppressor of hairless protein	8674407	Subcellular localization of Suppressor of Hairless in Drosophila sense organ cells during Notch signalling.

Q10475	IF4G_SCHPO	Eukaryotic translation initiation factor 4 gamma	12581158	Overproduction of a conserved domain of fission yeast and mammalian translation initiation factor eIF4G causes aberrant cell morphology and results in disruption of the localization of F-actin and the organization of microtubules.

Q8VHK2	CSKI1_RAT	Caskin-1	12040031	CASK participates in alternative tripartite complexes in which Mint 1 competes for binding with Caskin 1, a novel CASK-binding protein.

Q9NP81	SYSM_HUMAN	Seryl-tRNA synthetase, mitochondrial	10764807	Characterization and tRNA recognition of mammalian mitochondrial seryl-tRNA synthetase.

P01771	HV310_HUMAN	Ig heavy chain V-III region HIL	420800	Amino acid sequence of the VH region of human myeloma cryoimmunoglobulin IgG Hil.

Q01844	EWS_HUMAN	RNA-binding protein EWS	18320585	Identification of proteins interacting with protein arginine methyltransferase 8: the Ewing sarcoma (EWS) protein binds independent of its methylation state.

P82279	CRUM1_HUMAN	Crumbs homolog 1	10508521	Mutations in a human homologue of Drosophila crumbs cause retinitis pigmentosa (RP12).

P53618	COPB_HUMAN	Coatomer subunit beta	18556652	Scyl1, mutated in a recessive form of spinocerebellar neurodegeneration, regulates COPI-mediated retrograde traffic.

Q9UQC2	GAB2_HUMAN	GRB2-associated-binding protein 2	19172738	Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein.

Q9FRV1	CHIA_SECCE	Basic endochitinase A	14981295	Molecular cloning, functional expression, and mutagenesis of cDNA encoding class I chitinase from rye (Secale cereale) seeds.

Q96S59	RANB9_HUMAN	Ran-binding protein 9	12421467	RanBPM interacts with psoriasin in vitro and their expression correlates with specific clinical features in vivo in breast cancer.

P27777	HS16A_ORYSJ	16.9 kDa class I heat shock protein 1	15803416	Characterization of the genomic structures and selective expression profiles of nine class I small heat shock protein genes clustered on two chromosomes in rice (Oryza sativa L.).

O35696	SIA8B_MOUSE	Alpha-2,8-sialyltransferase 8B	7875291	Enzymatic activity of a developmentally regulated member of the sialyltransferase family (STX): evidence for alpha 2,8- sialyltransferase activity toward N-linked oligosaccharides.

P83317	FAR2_PENMO	FMRFamide-like neuropeptide FLP2	11959015	Seven novel FMRFamide-like neuropeptide sequences from the eyestalk of the giant tiger prawn Penaeus monodon.

P87122	YDL6_SCHPO	Putative cation exchanger C3A12.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P04637	P53_HUMAN	Cellular tumor antigen p53	17317671	The notch regulator MAML1 interacts with p53 and functions as a coactivator.

Q84TI7	HKT1_ARATH	Sodium transporter HKT1	12727868	Functional analysis of AtHKT1 in Arabidopsis shows that Na(+) recirculation by the phloem is crucial for salt tolerance.

Q9U6Z1	KM11_TRYCR	Kinetoplastid membrane protein 11	10668791	Molecular characterization of KMP11 from Trypanosoma cruzi: a cytoskeleton-associated protein regulated at the translational level.

P15085	CBPA1_HUMAN	Carboxypeptidase A1	2920728	Purification and properties of five different forms of human procarboxypeptidases.

Q96AP0	ACD_HUMAN	Adrenocortical dysplasia protein homolog	16880378	A critical role for TPP1 and TIN2 interaction in high-order telomeric complex assembly.

P36091	DCW1_YEAST	Mannan endo-1,6-alpha-mannosidase DCW1	12421307	Two homologous genes, DCW1 (YKL046c) and DFG5, are essential for cell growth and encode glycosylphosphatidylinositol (GPI)-anchored membrane proteins required for cell wall biogenesis in Saccharomyces cerevisiae.

Q04377	LCD1_YEAST	DNA damage checkpoint protein LCD1	11983176	Lcd1p recruits Mec1p to DNA lesions in vitro and in vivo.

P50527	STE20_SCHPO	Serine/threonine-protein kinase shk1/pak1	11972773	The p21-activated kinase, Shk1, is required for proper regulation of microtubule dynamics in the fission yeast, Schizosaccharomyces pombe.

Q9ESJ1	CABL1_MOUSE	CDK5 and ABL1 enzyme substrate 1	10873625	Molecular cloning of a cyclin-like protein associated with cyclin- dependent kinase 3 (cdk 3) in vivo.

Q16663	CCL15_HUMAN	C-C motif chemokine 15	9548457	Molecular cloning of leukotactin-1: a novel human beta-chemokine, a chemoattractant for neutrophils, monocytes, and lymphocytes, and a potent agonist at CC chemokine receptors 1 and 3.

P26599	PTBP1_HUMAN	Polypyrimidine tract-binding protein 1	10653975	Differential nuclear localization and nuclear matrix association of the splicing factors PSF and PTB.

O60149	YNSJ_SCHPO	Uncharacterized protein C18H10.19	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P68767	AMPA_ECOLI	Cytosol aminopeptidase	7616564	carP, involved in pyrimidine regulation of the Escherichia coli carbamoylphosphate synthetase operon encodes a sequence-specific DNA- binding protein identical to XerB and PepA, also required for resolution of ColEI multimers.

Q04675	SEN15_YEAST	tRNA-splicing endonuclease subunit SEN15	9200603	The yeast tRNA splicing endonuclease: a tetrameric enzyme with two active site subunits homologous to the archaeal tRNA endonucleases.

Q92734	TFG_HUMAN	Protein TFG	7565764	The DNA rearrangement that generates the TRK-T3 oncogene involves a novel gene on chromosome 3 whose product has a potential coiled-coil domain.

P18101	RL40_DROME	Ubiquitin-60S ribosomal protein L40	2165256	Sequence of a Drosophila cDNA encoding a ubiquitin gene fusion to a 52-aa ribosomal protein tail.

P39927	PTI1_YEAST	Protein PTI1	12773397	Pti1p and Ref2p found in association with the mRNA 3' end formation complex direct snoRNA maturation.

P40010	NUG1_YEAST	Nuclear GTP-binding protein NUG1	11583615	Identification of a 60S preribosomal particle that is closely linked to nuclear export.

Q9JJ73	RAMP3_RAT	Receptor activity-modifying protein 3	11556887	Cloning, characterization and central nervous system distribution of receptor activity modifying proteins in the rat.

Q8BGW1	FTO_MOUSE	Alpha-ketoglutarate-dependent dioxygenase FTO	19234441	Inactivation of the Fto gene protects from obesity.

P12107	COBA1_HUMAN	Collagen alpha-1(XI) chain	3182841	Cloning and sequencing of pro-alpha 1 (XI) collagen cDNA demonstrates that type XI belongs to the fibrillar class of collagens and reveals that the expression of the gene is not restricted to cartilagenous tissue.

O43747	AP1G1_HUMAN	AP-1 complex subunit gamma-1	9733768	Identification and characterization of novel clathrin adaptor-related proteins.

Q94K43	GSOX2_ARATH	Flavin-containing monooxygenase FMO GS-OX2	18799661	Subclade of flavin-monooxygenases involved in aliphatic glucosinolate biosynthesis.

P81172	HEPC_HUMAN	Hepcidin	11034317	LEAP-1, a novel highly disulfide-bonded human peptide exhibits antimicrobial activity.

P21918	DRD5_HUMAN	D(1B) dopamine receptor	1826762	Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1.

Q9M7T0	PRX2F_ARATH	Peroxiredoxin-2F, mitochondrial	12492832	The impact of oxidative stress on Arabidopsis mitochondria.

O14104	LYS12_SCHPO	Probable homoisocitrate dehydrogenase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q09792	PPK8_SCHPO	Serine/threonine-protein kinase ppk8	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q15743	OGR1_HUMAN	Ovarian cancer G-protein coupled receptor 1	8661159	Identification of human OGR1, a novel G protein-coupled receptor that maps to chromosome 14.

Q9VHV5	ARL8_DROME	ADP-ribosylation factor-like protein 8	16537643	An N-terminally acetylated Arf-like GTPase is localised to lysosomes and affects their motility.

Q8BG17	NOL12_MOUSE	Nucleolar protein 12	16430885	Molecular cloning and characterization of Nop25, a novel nucleolar RNA binding protein, highly conserved in vertebrate species.

Q7TNK0	SERC1_RAT	Serine incorporator 1	16120614	Serinc, an activity-regulated protein family, incorporates serine into membrane lipid synthesis.

Q68CJ9	CR3L3_HUMAN	Cyclic AMP-responsive element-binding protein 3-like protein 3	16469704	Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response.

P25655	NOT1_YEAST	General negative regulator of transcription subunit 1	10490603	The CCR4 and CAF1 proteins of the CCR4-NOT complex are physically and functionally separated from NOT2, NOT4, and NOT5.

P11234	RALB_HUMAN	Ras-related protein Ral-B	2120779	Chromosomal localization and cDNA sequence of human ralB, a GTP binding protein.

P10815	CG23_SCHPO	G2/mitotic-specific cyclin cdc13	2534559	Fission yeast cyclin: subcellular localisation and cell cycle regulation.

P36630	CG22_SCHPO	G2/mitotic-specific cyclin cig2	9614176	Cyclin B proteolysis and the cyclin-dependent kinase inhibitor rum1p are required for pheromone-induced G1 arrest in fission yeast.

P32073	GUAA_DICDI	GMP synthase [glutamine-hydrolyzing]	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P16620	PTP69_DROME	Tyrosine-protein phosphatase 69D	2554325	A family of receptor-linked protein tyrosine phosphatases in humans and Drosophila.

Q86UK0	ABCAC_HUMAN	ATP-binding cassette sub-family A member 12	12697999	Identification and characterization of a novel ABCA subfamily member, ABCA12, located in the lamellar ichthyosis region on 2q34.

P00740	FA9_HUMAN	Coagulation factor IX	2472424	Three point mutations in the factor IX genes of five hemophilia B patients. Identification strategy using localization by altered epitopes in their hemophilic proteins.

Q42112	RLA02_ARATH	60S acidic ribosomal protein P0-2	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

P25641	ATG15_YEAST	Putative lipase ATG15	11085977	Degradation of lipid vesicles in the yeast vacuole requires function of Cvt17, a putative lipase.

P83176	HCY1_CARMA	Hemocyanin subunit 1	2620501	The relationship between N-terminal sequences and immunological characterization of crustacean hemocyanins.

P47863	AQP4_RAT	Aquaporin-4	7528931	Molecular characterization of an aquaporin cDNA from brain: candidate osmoreceptor and regulator of water balance.

Q9S1E6	NRFH_WOLSU	Cytochrome c-type protein nrfH	10672190	A NapC/NirT-type cytochrome c (NrfH) is the mediator between the quinone pool and the cytochrome c nitrite reductase of Wolinella succinogenes.

P97814	PPIP1_MOUSE	Proline-serine-threonine phosphatase-interacting protein 1	9265651	PSTPIP: a tyrosine phosphorylated cleavage furrow-associated protein that is a substrate for a PEST tyrosine phosphatase.

P32480	HIR2_YEAST	Protein HIR2	8417331	Characterization of HIR1 and HIR2, two genes required for regulation of histone gene transcription in Saccharomyces cerevisiae.

P41180	CASR_HUMAN	Extracellular calcium-sensing receptor	7759551	Molecular cloning and functional expression of human parathyroid calcium receptor cDNAs.

P28263	UBC8_YEAST	Ubiquitin-conjugating enzyme E2-24 kDa	12686616	Catabolite degradation of fructose-1,6-bisphosphatase in the yeast Saccharomyces cerevisiae: a genome-wide screen identifies eight novel GID genes and indicates the existence of two degradation pathways.

P53819	YRF16_YEAST	Y' element ATP-dependent helicase protein 1 copy 6	9837911	Y'-Help1, a DNA helicase encoded by the yeast subtelomeric Y' element, is induced in survivors defective for telomerase.

Q00582	GTR1_YEAST	GTP-binding protein GTR1	1620108	Putative GTP-binding protein, Gtr1, associated with the function of the Pho84 inorganic phosphate transporter in Saccharomyces cerevisiae.

P53141	MLC1_YEAST	Myosin light chain 1	12456647	Mlc1p promotes septum closure during cytokinesis via the IQ motifs of the vesicle motor Myo2p.

Q14938	NFIX_HUMAN	Nuclear factor 1 X-type	7590749	Chromosomal localization of the four genes (NFIA, B, C, and X) for the human transcription factor nuclear factor I by FISH.

Q6P9X9	PARM1_RAT	Prostate androgen-regulated mucin-like protein 1 homolog	10499539	A novel gene overexpressed in the prostate of castrated rats: hormonal regulation, relationship to apoptosis and to acquired prostatic cell androgen independence.

Q06263	VTA1_YEAST	Vacuolar protein sorting-associated protein VTA1	14562095	Global analysis of protein localization in budding yeast.

Q9S7J8	AHM5_ARATH	Copper-transporting ATPase RAN1	10319818	Responsive-to-antagonist 1, a Menkes/Wilson disease-related copper transporter, is required for ethylene signaling in Arabidopsis.

Q9JK30	ORC3_MOUSE	Origin recognition complex subunit 3	10702681	Identification and chromosomal localization of murine ORC3, a new member of the mouse origin recognition complex.

Q9P7D0	YOFJ_SCHPO	Uncharacterized protein P4H10.19c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q39026	MPK6_ARATH	Mitogen-activated protein kinase 6	10713056	Microbial elicitors induce activation and dual phosphorylation of the Arabidopsis thaliana MAPK 6.

Q86YH6	DLP1_HUMAN	Decaprenyl-diphosphate synthase subunit 2	16262699	Characterization of solanesyl and decaprenyl diphosphate synthases in mice and humans.

Q1PFJ4	PUP17_ARATH	Probable purine permease 17	10662864	A new family of high-affinity transporters for adenine, cytosine, and purine derivatives in Arabidopsis.

P36004	KKQ8_YEAST	Probable serine/threonine-protein kinase KKQ8	14562095	Global analysis of protein localization in budding yeast.

O09046	OXLA_MOUSE	L-amino-acid oxidase	15383589	IL-4-induced gene-1 is a leukocyte L-amino acid oxidase with an unusual acidic pH preference and lysosomal localization.

Q9U9Y8	NLK_CAEEL	Serine/threonine kinase NLK	10380924	WRM-1 activates the LIT-1 protein kinase to transduce anterior/posterior polarity signals in C. elegans.

P60709	ACTB_HUMAN	Actin, cytoplasmic 1	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

Q96JB5	CK5P3_HUMAN	CDK5 regulatory subunit-associated protein 3	10721722	Cloning of three novel neuronal Cdk5 activator binding proteins.

P25108	ACHA_RAT	Acetylcholine receptor subunit alpha	1702709	Primary structure and functional expression of the alpha-, beta-, gamma-, delta- and epsilon-subunits of the acetylcholine receptor from rat muscle.

Q04952	FKS3_YEAST	1,3-beta-glucan synthase component FKS3	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Q90ZF9	CENPH_CHICK	Centromere protein H	15713649	The functional region of CENP-H interacts with the Nuf2 complex that localizes to centromere during mitosis.

Q920Q6	MSI2H_MOUSE	RNA-binding protein Musashi homolog 2	12407178	RNA-binding protein Musashi family: roles for CNS stem cells and a subpopulation of ependymal cells revealed by targeted disruption and antisense ablation.

Q54SF9	MHCKD_DICDI	Myosin heavy chain kinase D	15987738	Multiple myosin II heavy chain kinases: roles in filament assembly control and proper cytokinesis in Dictyostelium.

Q8C7G5	APOA5_MOUSE	Apolipoprotein A-V	11588264	An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing.

Q05932	FOLC_HUMAN	Folylpolyglutamate synthase, mitochondrial	7721888	Upstream organization of and multiple transcripts from the human folylpoly-gamma-glutamate synthetase gene.

O60162	YG23_SCHPO	Uncharacterized protein C19F5.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O08638	MYH11_MOUSE	Myosin-11	8593698	Preferential differentiation of P19 mouse embryonal carcinoma cells into smooth muscle cells. Use of retinoic acid and antisense against the central nervous system-specific POU transcription factor Brn-2.

Q13829	BACD2_HUMAN	BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2	19782033	Cullin mediates degradation of RhoA through evolutionarily conserved BTB adaptors to control actin cytoskeleton structure and cell movement.

P51531	SMCA2_HUMAN	Probable global transcription activator SNF2L2	8223438	A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor.

Q07923	LOT6_YEAST	NAD(P)H-dependent FMN reductase LOT6	14562095	Global analysis of protein localization in budding yeast.

O14817	TSN4_HUMAN	Tetraspanin-4	9360996	NAG-2, a novel transmembrane-4 superfamily (TM4SF) protein that complexes with integrins and other TM4SF proteins.

Q8K4S7	CBLB_RAT	E3 ubiquitin-protein ligase CBL-B	14604964	Negative regulation of FcepsilonRI-mediated mast cell activation by a ubiquitin-protein ligase Cbl-b.

P05059	CMGA_BOVIN	Chromogranin-A	2756155	Isolation and characterization of bovine pancreastatin.

Q9VLJ6	ACER_DROME	Angiotensin-converting enzyme-related protein	9839949	The Drosophila melanogaster-related angiotensin-I-converting enzymes Acer and Ance -- distinct enzymic characteristics and alternative expression during pupal development.

P29692	EF1D_HUMAN	Elongation factor 1-delta	8334168	The human leucine zipper-containing guanine-nucleotide exchange protein elongation factor-1 delta.

Q9PW28	IF4EB_DANRE	Eukaryotic translation initiation factor 4E-1B	14701818	Two zebrafish eIF4E family members are differentially expressed and functionally divergent.

Q6URK4	ROA3_RAT	Heterogeneous nuclear ribonucleoprotein A3	11886857	Heterogeneous nuclear ribonucleoprotein A3, a novel RNA trafficking response element-binding protein.

Q9D7E3	OVCA2_MOUSE	Ovarian cancer-associated gene 2 protein homolog	11527402	Cloning, structure, and expression of the mouse Ovca1 gene.

P51142	DVL2_XENLA	Segment polarity protein dishevelled homolog DVL-2	7600981	Dorsalizing and neuralizing properties of Xdsh, a maternally expressed Xenopus homolog of dishevelled.

O88813	ACSL5_RAT	Long-chain-fatty-acid--CoA ligase 5	16263710	Rat long chain acyl-CoA synthetase 5 increases fatty acid uptake and partitioning to cellular triacylglycerol in McArdle-RH7777 cells.

Q19705	ARL2_CAEEL	ADP-ribosylation factor-like protein 2	15576487	Functional genomic analysis of the ADP-ribosylation factor family of GTPases: phylogeny among diverse eukaryotes and function in C. elegans.

Q9UBL3	ASH2L_HUMAN	Set1/Ash2 histone methyltransferase complex subunit ASH2	12670868	Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell- proliferation factor HCF-1.

O13858	YEX7_SCHPO	Uncharacterized protein C1A6.07	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

P26371	KRA59_HUMAN	Keratin-associated protein 5-9	1703541	Structure and expression of genes for a class of cysteine-rich proteins of the cuticle layers of differentiating wool and hair follicles.

Q24106	HID_DROME	Cell death protein W	7622034	The head involution defective gene of Drosophila melanogaster functions in programmed cell death.

P39081	PCF11_YEAST	Protein PCF11	11344258	Five subunits are required for reconstitution of the cleavage and polyadenylation activities of Saccharomyces cerevisiae cleavage factor I.

Q9LN63	BZR2_ARATH	Protein BRASSINAZOLE-RESISTANT 2	12007405	BES1 accumulates in the nucleus in response to brassinosteroids to regulate gene expression and promote stem elongation.

Q9Y6Q6	TNR11_HUMAN	Tumor necrosis factor receptor superfamily member 11A	18606301	Human osteoclast-poor osteopetrosis with hypogammaglobulinemia due to TNFRSF11A (RANK) mutations.

Q9VKM1	PIWI_DROME	Protein piwi	9851978	A novel class of evolutionarily conserved genes defined by piwi are essential for stem cell self-renewal.

O35594	IFT81_MOUSE	Intraflagellar transport protein 81 homolog	12549821	Identification of human CDV-1R and mouse Cdv-1R, two novel proteins with putative signal peptides, especially highly expressed in testis and increased with the male sex maturation.

Q9US46	ITT1_SCHPO	E3 ubiquitin-protein ligase itt1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O75339	CILP1_HUMAN	Cartilage intermediate layer protein 1	9722584	Cloning and deduced amino acid sequence of a novel cartilage protein (CILP) identifies a proform including a nucleotide pyrophosphohydrolase.

P13681	PP11_SCHPO	Serine/threonine-protein phosphatase PP1-1	2544298	The fission yeast dis2+ gene required for chromosome disjoining encodes one of two putative type 1 protein phosphatases.

Q9EPA7	NMNA1_MOUSE	Nicotinamide mononucleotide adenylyltransferase 1	15381699	The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells.

P43220	GLP1R_HUMAN	Glucagon-like peptide 1 receptor	8405712	Cloning and functional expression of the human islet GLP-1 receptor. Demonstration that exendin-4 is an agonist and exendin-(9-39) an antagonist of the receptor.

Q8W420	ADO2_ARATH	Adagio protein 2	11752379	A role for LKP2 in the circadian clock of Arabidopsis.

Q10269	AREH1_SCHPO	Probable sterol O-acyltransferase 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P05455	LA_HUMAN	Lupus La protein	3192525	Genomic structure and amino acid sequence domains of the human La autoantigen.

P01215	GLHA_HUMAN	Glycoprotein hormones alpha chain	6774759	Studies on the disulfide bonds in human pituitary follicle- stimulating hormone.

Q7SXW0	S2539_DANRE	Solute carrier family 25 member 39	19656490	Discovery of genes essential for heme biosynthesis through large- scale gene expression analysis.

Q9NZM3	ITSN2_HUMAN	Intersectin-2	9630982	Cloning of ligand targets: systematic isolation of SH3 domain- containing proteins.

P43092	CARP3_CANAL	Candidapepsin-3	9043112	Analysis of secreted aspartic proteinases from Candida albicans: purification and characterization of individual Sap1, Sap2 and Sap3 isoenzymes.

Q61161	M4K2_MOUSE	Mitogen-activated protein kinase kinase kinase kinase 2	8643544	In its active form, the GTP-binding protein rab8 interacts with a stress-activated protein kinase.

O60825	F262_HUMAN	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2	9652401	Sequence and structure of the human 6-phosphofructo-2- kinase/fructose-2,6-bisphosphatase heart isoform gene (PFKFB2).

Q9NQW7	XPP1_HUMAN	Xaa-Pro aminopeptidase 1	9465902	Isolation and sequence analysis of a human cDNA clone (XPNPEPL) homologous to X-prolyl aminopeptidase (aminopeptidase P).

Q76KJ5	RPA34_MOUSE	DNA-directed RNA polymerase I subunit RPA34	15226435	Multiple protein-protein interactions by RNA polymerase I-associated factor PAF49 and role of PAF49 in rRNA transcription.

P22147	XRN1_YEAST	5'-3' exoribonuclease 1	16240118	A role for KEM1 at the START of the cell cycle in Saccharomyces cerevisiae.

Q9NUV7	SPTC3_HUMAN	Serine palmitoyltransferase 3	19416851	Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities.

P42949	TIM16_YEAST	Mitochondrial import inner membrane translocase subunit TIM16	14981507	Pam16 has an essential role in the mitochondrial protein import motor.

P34331	PLK1_CAEEL	Serine/threonine-protein kinase plk-1	10660671	The polo-like kinase PLK-1 is required for nuclear envelope breakdown and the completion of meiosis in Caenorhabditis elegans.

Q92570	NR4A3_HUMAN	Nuclear receptor subfamily 4 group A member 3	8634690	Oncogenic conversion of a novel orphan nuclear receptor by chromosome translocation.

Q0VGM9	RTEL1_MOUSE	Regulator of telomere elongation helicase 1	15210109	Regulation of murine telomere length by Rtel: an essential gene encoding a helicase-like protein.

P70662	LDB1_MOUSE	LIM domain-binding protein 1	11882901	Ubiquitination-dependent cofactor exchange on LIM homeodomain transcription factors.

Q8CHZ9	MTERF_MOUSE	Transcription termination factor, mitochondrial	15582606	Cloning and characterization of mouse mTERF encoding a mitochondrial transcriptional termination factor.

Q8LRK8	HDA18_ARATH	Histone deacetylase 18	16176989	Histone acetylation affects expression of cellular patterning genes in the Arabidopsis root epidermis.

P34216	EDE1_YEAST	EH domain-containing and endocytosis protein 1	16563434	Structural basis for monoubiquitin recognition by the Ede1 UBA domain.

P02768	ALBU_HUMAN	Serum albumin	10940303	Binding of the general anesthetics propofol and halothane to human serum albumin. High resolution crystal structures.

O60158	YHYA_SCHPO	HTH APSES-type DNA-binding domain-containing protein C19C7.10	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P49459	UBE2A_HUMAN	Ubiquitin-conjugating enzyme E2 A	20061386	The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.

O13924	HASP_SCHPO	Serine/threonine-protein kinase haspin homolog C23C4.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P25296	CANB_YEAST	Calcineurin subunit B	1321337	Regulatory subunit (CNB1 gene product) of yeast Ca2+/calmodulin- dependent phosphoprotein phosphatases is required for adaptation to pheromone.

P17121	SAC7_YEAST	GTPase-activating protein SAC7	9038344	The yeast phosphatidylinositol kinase homolog TOR2 activates RHO1 and RHO2 via the exchange factor ROM2.

P35269	T2FA_HUMAN	General transcription factor IIF subunit 1	16548883	Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection.

P34147	RACA_DICDI	Rho-related protein racA	15509655	Cellular distribution and functions of wild-type and constitutively activated Dictyostelium PakB.

Q62818	EI2BB_RAT	Translation initiation factor eIF-2B subunit beta	9139680	Subunit assembly and guanine nucleotide exchange activity of eukaryotic initiation factor-2B expressed in Sf9 cells.

P46415	ADHX_DROME	Alcohol dehydrogenase class-3	8197167	Fundamental molecular differences between alcohol dehydrogenase classes.

Q9US27	VPS66_SCHPO	Uncharacterized acyltransferase vps66	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9JID9	SH2B2_MOUSE	SH2B adapter protein 2	10872802	Molecular cloning of the mouse APS as a member of the Lnk family adaptor proteins.

Q07824	TPO1_YEAST	Polyamine transporter 1	11171066	Multiple polyamine transport systems on the vacuolar membrane in yeast.

P32004	L1CAM_HUMAN	Neural cell adhesion molecule L1	7920659	X-linked spastic paraplegia (SPG1), MASA syndrome and X-linked hydrocephalus result from mutations in the L1 gene.

Q9NRR5	UBQL4_HUMAN	Ubiquilin-4	11001934	Identification and characterization of an ataxin-1-interacting protein: A1Up, a ubiquitin-like nuclear protein.

D3ZDK2	UB2D1_RAT	Ubiquitin-conjugating enzyme E2 D1	18359941	Members of the E2D (UbcH5) family mediate the ubiquitination of the conserved cysteine of Pex5p, the peroxisomal import receptor.

O75154	RFIP3_HUMAN	Rab11 family-interacting protein 3	15601896	The FIP3-Rab11 protein complex regulates recycling endosome targeting to the cleavage furrow during late cytokinesis.

Q13064	MKRN3_HUMAN	Probable E3 ubiquitin-protein ligase makorin-3	10196367	A novel imprinted gene, encoding a RING zinc-finger protein, and overlapping antisense transcript in the Prader-Willi syndrome critical region.

P33887	IF2G_RABIT	Eukaryotic translation initiation factor 2 subunit 3	3592677	The purification and characterization of subunits alpha, beta, and gamma from the rabbit reticulocyte eukaryotic initiation factor 2.

Q9Y7T4	ATG1_SCHPO	Serine/threonine-protein kinase atg1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q27J81	INF2_HUMAN	Inverted formin-2	20023659	Mutations in the formin gene INF2 cause focal segmental glomerulosclerosis.

P53327	SLH1_YEAST	Antiviral helicase SLH1	10922069	3' poly(A) is dispensable for translation.

Q99190	TSC13_YEAST	Enoyl reductase TSC13	11113186	Tsc13p is required for fatty acid elongation and localizes to a novel structure at the nuclear-vacuolar interface in Saccharomyces cerevisiae.

P07256	QCR1_YEAST	Cytochrome b-c1 complex subunit 1, mitochondrial	3023384	Assembly of the mitochondrial membrane system. Characterization of COR1, the structural gene for the 44-kilodalton core protein of yeast coenzyme QH2-cytochrome c reductase.

Q12045	VIK1_YEAST	Spindle pole body-associated protein VIK1	11729143	The Kar3-interacting protein Cik1p plays a critical role in passage through meiosis I in Saccharomyces cerevisiae.

Q9HD15	SRA1_HUMAN	Steroid receptor RNA activator 1	10199399	A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex.

P01766	HV305_HUMAN	Ig heavy chain V-III region BRO	65324	Comparative studies on monotypic IgM lambda and IgG kappa from an individual patient. III. The complete amino acid sequence of the VH region of the IgM paraprotein.

P40879	S26A3_HUMAN	Chloride anion exchanger	8896562	Mutations of the Down-regulated in adenoma (DRA) gene cause congenital chloride diarrhoea.

Q8SAS8	TBSYN_HYPAN	Trihydroxybenzophenone synthase	12795704	Benzophenone synthase and chalcone synthase from Hypericum androsaemum cell cultures: cDNA cloning, functional expression, and site-directed mutagenesis of two polyketide synthases.

Q39016	CDPKB_ARATH	Calcium-dependent protein kinase 11	17921317	Two calcium-dependent protein kinases, CPK4 and CPK11, regulate abscisic acid signal transduction in Arabidopsis.

P61019	RAB2A_HUMAN	Ras-related protein Rab-2A	2501306	The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion.

A2ARA8	ITA8_MOUSE	Integrin alpha-8	10742111	Stereocilia defects in the sensory hair cells of the inner ear in mice deficient in integrin alpha8beta1.

O60870	KIN17_HUMAN	DNA/RNA-binding protein KIN17	12359749	Human kin17 protein directly interacts with the simian virus 40 large T antigen and inhibits DNA replication.

Q15208	STK38_HUMAN	Serine/threonine-protein kinase 38	19377461	GlcNAcylation of a histone methyltransferase in retinoic-acid-induced granulopoiesis.

P08172	ACM2_HUMAN	Muscarinic acetylcholine receptor M2	16548883	Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection.

A5HZ59	CEO_CLOBH	N(5)-(carboxyethyl)ornithine synthase	19933367	The gene CBO0515 from Clostridium botulinum strain Hall A encodes the rare enzyme N5-(carboxyethyl) ornithine synthase, EC 1.5.1.24.

Q969G3	SMCE1_HUMAN	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1	9435219	Architectural DNA binding by a high-mobility-group/kinesin-like subunit in mammalian SWI/SNF-related complexes.

Q04623	ECM18_YEAST	Protein ECM18	14562095	Global analysis of protein localization in budding yeast.

Q9Y3M8	STA13_HUMAN	StAR-related lipid transfer protein 13	14697242	Chromosome 13q12 encoded Rho GTPase activating protein suppresses growth of breast carcinoma cells, and yeast two-hybrid screen shows its interaction with several proteins.

Q9JHD2	KAT2A_MOUSE	Histone acetyltransferase KAT2A	9742083	Mammalian GCN5 and P/CAF acetyltransferases have homologous amino- terminal domains important for recognition of nucleosomal substrates.

Q15772	SPEG_HUMAN	Striated muscle preferentially expressed protein kinase	8663449	APEG-1, a novel gene preferentially expressed in aortic smooth muscle cells, is down-regulated by vascular injury.

Q9P0G3	KLK14_HUMAN	Kallikrein-14	18482984	Major role of human KLK14 in seminal clot liquefaction.

Q9Z214	HOME1_RAT	Homer protein homolog 1	9069287	Homer: a protein that selectively binds metabotropic glutamate receptors.

P32324	EF2_YEAST	Elongation factor 2	12410829	Characterization of interaction sites in the Saccharomyces cerevisiae ribosomal stalk components.

O49397	ARR10_ARATH	Two-component response regulator ARR10	12215502	Molecular structure of the GARP family of plant Myb-related DNA binding motifs of the Arabidopsis response regulators.

P40504	KTR7_YEAST	Probable mannosyltransferase KTR7	9090056	Completion of the Saccharomyces cerevisiae genome sequence allows identification of KTR5, KTR6 and KTR7 and definition of the nine- membered KRE2/MNT1 mannosyltransferase gene family in this organism.

P23796	RIT1_YEAST	tRNA A64-2'-O-ribosylphosphate transferase	7954819	Rit1, a tRNA backbone-modifying enzyme that mediates initiator and elongator tRNA discrimination.

P16257	TSPO_RAT	Translocator protein	2555358	Molecular cloning and expression of cDNA encoding a peripheral-type benzodiazepine receptor.

Q9Y7P6	MUG72_SCHPO	Meiotically up-regulated gene 72 protein	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

Q99PV8	BC11B_MOUSE	B-cell lymphoma/leukemia 11B	12565905	Homozygous deletions and point mutations of the Rit1/Bcl11b gene in gamma-ray induced mouse thymic lymphomas.

Q9Y5E8	PCDBF_HUMAN	Protocadherin beta-15	10380929	A striking organization of a large family of human neural cadherin- like cell adhesion genes.

P04053	TDT_HUMAN	DNA nucleotidylexotransferase	2863268	Expression of human terminal deoxynucleotidyl transferase in Escherichia coli.

O22152	YAB1_ARATH	Axial regulator YABBY 1	10323860	FILAMENTOUS FLOWER, a meristem and organ identity gene of Arabidopsis, encodes a protein with a zinc finger and HMG-related domains.

P54398	FBP2_DROME	Fat body protein 2	1920455	Drosophila fat body protein P6 and alcohol dehydrogenase are derived from a common ancestral protein.

P45383	RECA_VIBCH	Protein recA	8058040	Gene sequence of recA+ and construction of recA mutants of Vibrio cholerae.

Q6PCP7	GP156_MOUSE	Probable G-protein coupled receptor 156	12591167	Molecular cloning and characterization of a novel GABA(B)-related G- protein coupled receptor.

Q9FZ59	PEPR2_ARATH	Leucine-rich repeat receptor-like protein kinase PEPR2	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q21952	NUF2_CAEEL	Kinetochore protein Nuf2 homolog	11402066	HIM-10 is required for kinetochore structure and function on Caenorhabditis elegans holocentric chromosomes.

Q9UBL3	ASH2L_HUMAN	Set1/Ash2 histone methyltransferase complex subunit ASH2	19556245	On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex.

P38811	TRA1_YEAST	Transcription-associated protein 1	10487762	NuA4, an essential transcription adaptor/histone H4 acetyltransferase complex containing Esa1p and the ATM-related cofactor Tra1p.

Q15399	TLR1_HUMAN	Toll-like receptor 1	9435236	A family of human receptors structurally related to Drosophila Toll.

P19938	DAAA_BACYM	D-alanine aminotransferase	9538014	Crystallographic study of steps along the reaction pathway of D-amino acid aminotransferase.

P77161	GLXR_ECOLI	2-hydroxy-3-oxopropionate reductase	10601204	Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.

Q9ZQX6	ETOL1_ARATH	ETO1-like protein 1	15118728	Regulation of ethylene gas biosynthesis by the Arabidopsis ETO1 protein.

Q12530	RMP1_YEAST	Ribonuclease MRP protein subunit RMP1	15637077	Characterization and purification of Saccharomyces cerevisiae RNase MRP reveals a new unique protein component.

Q38845	2AAA_ARATH	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform	8641277	A mutation in protein phosphatase 2A regulatory subunit A affects auxin transport in Arabidopsis.

Q07657	SHS1_YEAST	Seventh homolog of septin 1	12058072	Cell cycle-dependent assembly of a Gin4-septin complex.

Q08649	ESA1_YEAST	Histone acetyltransferase ESA1	10487762	NuA4, an essential transcription adaptor/histone H4 acetyltransferase complex containing Esa1p and the ATM-related cofactor Tra1p.

P53178	ALG13_YEAST	UDP-N-acetylglucosamine transferase subunit ALG13	16100110	Alg14 recruits Alg13 to the cytoplasmic face of the endoplasmic reticulum to form a novel bipartite UDP-N-acetylglucosamine transferase required for the second step of N-linked glycosylation.

O94464	YBR6_SCHPO	Uncharacterized protein C23G7.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q700D2	JKD_ARATH	Zinc finger protein JACKDAW	17785527	Arabidopsis JACKDAW and MAGPIE zinc finger proteins delimit asymmetric cell division and stabilize tissue boundaries by restricting SHORT-ROOT action.

P98177	FOXO4_HUMAN	Forkhead box protein O4	16272144	Regulation of intracellular localization and transcriptional activity of FOXO4 by protein kinase B through phosphorylation at the motif sites conserved among the FOXO family.

Q9P329	YI48_SCHPO	Putative cell agglutination protein C1348.08c/C977.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P15311	EZRI_HUMAN	Ezrin	15498789	Role of a novel EGF-like domain-containing gene NGX6 in cell adhesion modulation in nasopharyngeal carcinoma cells.

O13290	DYHC_SCHPO	Dynein heavy chain, cytoplasmic	10366596	A cytoplasmic dynein heavy chain is required for oscillatory nuclear movement of meiotic prophase and efficient meiotic recombination in fission yeast.

P38962	TVP23_YEAST	Golgi apparatus membrane protein TVP23	16107716	Immunoisolaton of the yeast Golgi subcompartments and characterization of a novel membrane protein, Svp26, discovered in the Sed5-containing compartments.

Q9Y3C8	UFC1_HUMAN	Ubiquitin-fold modifier-conjugating enzyme 1	20018847	A novel type of E3 ligase for the Ufm1 conjugation system.

Q9UHP7	CLC2D_HUMAN	C-type lectin domain family 2 member D	10541800	Cloning of a new lectin-like receptor expressed on human NK cells.

Q53079	PSB1_RHOER	Proteasome subunit beta 1	9000518	Subunit topology of the Rhodococcus proteasome.

O43709	WBS22_HUMAN	Uncharacterized methyltransferase WBSCR22	11124703	Characterization of 16 novel human genes showing high similarity to yeast sequences.

Q9VEC1	MED17_DROME	Mediator of RNA polymerase II transcription subunit 17	11259581	Drosophila Mediator complex is broadly utilized by diverse gene- specific transcription factors at different types of core promoters.

P51592	HYD_DROME	E3 ubiquitin-protein ligase hyd	12421709	The ubiquitin ligase Hyperplastic discs negatively regulates hedgehog and decapentaplegic expression by independent mechanisms.

Q9Y7J9	MCP5_SCHPO	Meiotic coiled-coil protein 5	16624923	Fission yeast Num1p is a cortical factor anchoring dynein and is essential for the horse-tail nuclear movement during meiotic prophase.

Q9HDY9	MAM3_SCHPO	M cell-type agglutination protein mam3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P39940	RSP5_YEAST	E3 ubiquitin-protein ligase RSP5	15247235	NPR1 kinase and RSP5-BUL1/2 ubiquitin ligase control GLN3-dependent transcription in Saccharomyces cerevisiae.

P93050	RKF3_ARATH	Probable LRR receptor-like serine/threonine-protein kinase RKF3	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q9LDY8	NAC55_ARATH	NAC domain-containing protein 55	15319476	Isolation and functional analysis of Arabidopsis stress-inducible NAC transcription factors that bind to a drought-responsive cis-element in the early responsive to dehydration stress 1 promoter.

Q9GSX9	RIC8_CAEEL	Synembryn	15479639	RIC-8 is required for GPR-1/2-dependent Galpha function during asymmetric division of C. elegans embryos.

Q47KB1	DYP_THEFY	Peroxidase Tfu_3078	19967355	A robust and extracellular heme-containing peroxidase from Thermobifida fusca as prototype of a bacterial peroxidase superfamily.

Q9AR19	GCN5_ARATH	Histone acetyltransferase GCN5	16763149	TOPLESS regulates apical embryonic fate in Arabidopsis.

O14649	KCNK3_HUMAN	Potassium channel subfamily K member 3	9312005	TASK, a human background K+ channel to sense external pH variations near physiological pH.

P18508	GBRG2_RAT	Gamma-aminobutyric acid receptor subunit gamma-2	2561970	Two novel GABAA receptor subunits exist in distinct neuronal subpopulations.

Q16576	RBBP7_HUMAN	Histone-binding protein RBBP7	7503932	Dual retinoblastoma-binding proteins with properties related to a negative regulator of ras in yeast.

O75604	UBP2_HUMAN	Ubiquitin carboxyl-terminal hydrolase 2	17290220	The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2.

O82333	GH31_ARATH	Probable indole-3-acetic acid-amido synthetase GH3.1	15659623	Characterization of an Arabidopsis enzyme family that conjugates amino acids to indole-3-acetic acid.

P34161	YOX1_YEAST	Homeobox protein YOX1	8096171	In vitro binding to the leucine tRNA gene identifies a novel yeast homeobox gene.

Q03214	ECM5_YEAST	Protein ECM5	9335584	Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae.

P37702	BGL38_ARATH	Myrosinase 1	16640593	Arabidopsis myrosinases TGG1 and TGG2 have redundant function in glucosinolate breakdown and insect defense.

P40796	LA_DROME	La protein homolog	8035818	La proteins from Drosophila melanogaster and Saccharomyces cerevisiae: a yeast homolog of the La autoantigen is dispensable for growth.

Q96BQ1	FAM3D_HUMAN	Protein FAM3D	12160727	Cloning, expression, and initial characterization of a novel cytokine-like gene family.

P18009	IPA4_SHIFL	Probable E3 ubiquitin-protein ligase ipaH4.5	11418613	Shigella protein IpaH(9.8) is secreted from bacteria within mammalian cells and transported to the nucleus.

Q9ES54	NPL4_RAT	Nuclear protein localization protein 4 homolog	10811609	A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways.

Q9GZU5	NYX_HUMAN	Nyctalopin	11062471	Mutations in NYX, encoding the leucine-rich proteoglycan nyctalopin, cause X-linked complete congenital stationary night blindness.

P10599	THIO_HUMAN	Thioredoxin	3170595	Cloning and expression of a cDNA for human thioredoxin.

P53271	COG2_YEAST	Conserved oligomeric Golgi complex subunit 2	12011112	The Sec34/Sec35p complex, a Ypt1p effector required for retrograde intra-Golgi trafficking, interacts with Golgi SNAREs and COPI vesicle coat proteins.

P40358	JEM1_YEAST	DnaJ-like chaperone JEM1	9148890	The yeast JEM1p is a DnaJ-like protein of the endoplasmic reticulum membrane required for nuclear fusion.

P80310	S10AC_PIG	Protein S100-A12	7961855	Primary structure and binding properties of calgranulin C, a novel S100-like calcium-binding protein from pig granulocytes.

O95696	BRD1_HUMAN	Bromodomain-containing protein 1	10602503	The cloning, mapping and expression of a novel gene, BRL, related to the AF10 leukaemia gene.

Q9UUG8	TUP12_SCHPO	Transcriptional repressor tup12	10567571	Conservation of histone binding and transcriptional repressor functions in a Schizosaccharomyces pombe Tup1p homolog.

Q76PC4	YQ72_SCHPO	UPF0649 protein C1442.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q64732	FOXB1_MOUSE	Forkhead box protein B1	8306889	The formation and maintenance of the definitive endoderm lineage in the mouse: involvement of HNF3/forkhead proteins.

P38806	YNG2_YEAST	Chromatin modification-related protein YNG2	15485911	The Yaf9 component of the SWR1 and NuA4 complexes is required for proper gene expression, histone H4 acetylation, and Htz1 replacement near telomeres.

Q811P8	RHG32_MOUSE	Rho GTPase-activating protein 32	12454018	Characterization of a brain-specific Rho GTPase-activating protein, p200RhoGAP.

P50572	GBRR1_RAT	Gamma-aminobutyric acid receptor subunit rho-1	8905713	The rho 1 GABA receptor cloned from rat retina is down-modulated by protons.

P18850	ATF6A_HUMAN	Cyclic AMP-dependent transcription factor ATF-6 alpha	9271374	Interaction of ATF6 and serum response factor.

P35718	RPC8_YEAST	DNA-directed RNA polymerase III subunit RPC8	8065349	C25, an essential RNA polymerase III subunit related to the RNA polymerase II subunit RPB7.

Q17307	TRA2_CAEBR	Sex-determining transformer protein 2	11250902	The TRA-1 transcription factor binds TRA-2 to regulate sexual fates in Caenorhabditis elegans.

Q9BU89	DOHH_HUMAN	Deoxyhypusine hydroxylase	16371467	Molecular cloning, expression, and structural prediction of deoxyhypusine hydroxylase: a HEAT-repeat-containing metalloenzyme.

P06536	GCR_RAT	Glucocorticoid receptor	8618925	Steroid receptor heterodimerization demonstrated in vitro and in vivo.

Q6X7K1	WOX2_ARATH	WUSCHEL-related homeobox 2	14711878	Expression dynamics of WOX genes mark cell fate decisions during early embryonic patterning in Arabidopsis thaliana.

Q9LN63	BZR2_ARATH	Protein BRASSINAZOLE-RESISTANT 2	15680330	A new class of transcription factors mediates brassinosteroid- regulated gene expression in Arabidopsis.

Q99816	TS101_HUMAN	Tumor susceptibility gene 101 protein	18256029	Identification of Alix-type and non-Alix-type ALG-2-binding sites in human phospholipid scramblase 3: differential binding to an alternatively spliced isoform and amino acid-substituted mutants.

Q99MQ5	COPA1_MOUSE	Collagen alpha-1(XXV) chain	11927537	CLAC: a novel Alzheimer amyloid plaque component derived from a transmembrane precursor, CLAC-P/collagen type XXV.

P84281	PA3A_RANPA	Palustrin-3a	11087945	Multiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris.

P35236	PTN7_HUMAN	Tyrosine-protein phosphatase non-receptor type 7	1530918	Cloning and expression of an inducible lymphoid-specific, protein tyrosine phosphatase (HePTPase).

Q01454	CTF4_YEAST	DNA polymerase alpha-binding protein	1341195	CTF4 (CHL15) mutants exhibit defective DNA metabolism in the yeast Saccharomyces cerevisiae.

P39962	KC13_YEAST	Casein kinase I homolog 3	8816449	Prenylated isoforms of yeast casein kinase I, including the novel Yck3p, suppress the gcs1 blockage of cell proliferation from stationary phase.

Q9Y257	KCNK6_HUMAN	Potassium channel subfamily K member 6	10075682	TWIK-2, a new weak inward rectifying member of the tandem pore domain potassium channel family.

P0AFA7	NHAB_ECOLI	Na(+)/H(+) antiporter nhaB	7822245	The NhaB Na+/H+ antiporter is essential for intracellular pH regulation under alkaline conditions in Escherichia coli.

P01119	RAS1_YEAST	Ras-like protein 1	3513173	Processing and fatty acid acylation of RAS1 and RAS2 proteins in Saccharomyces cerevisiae.

P09201	F16P_YEAST	Fructose-1,6-bisphosphatase	2841162	Isolation and primary structure of the gene encoding fructose-1,6- bisphosphatase from Saccharomyces cerevisiae.

P40021	ZRG8_YEAST	Zinc-regulated protein 8	14562095	Global analysis of protein localization in budding yeast.

Q9SHD3	CCU21_ARATH	Cyclin-U2-1	15197472	Molecular characterization of Arabidopsis PHO80-like proteins, a novel class of CDKA;1-interacting cyclins.

Q04724	TLE1_HUMAN	Transducin-like enhancer protein 1	8687460	Molecular interaction between TLE1 and the carboxyl-terminal domain of HES-1 containing the WRPW motif.

P29459	IL12A_HUMAN	Interleukin-12 subunit alpha	2204066	Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells.

Q9P2R7	SUCB1_HUMAN	Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial	9765291	Genetic evidence for the expression of ATP- and GTP-specific succinyl-CoA synthetases in multicellular eucaryotes.

P35555	FBN1_HUMAN	Fibrillin-1	1860873	Purification and partial characterization of fibrillin, a cysteine- rich structural component of connective tissue microfibrils.

Q05670	FUS2_YEAST	Nuclear fusion protein FUS2	7559752	Fus2 localizes near the site of cell fusion and is required for both cell fusion and nuclear alignment during zygote formation.

P18825	ADA2C_HUMAN	Alpha-2C adrenergic receptor	9371698	Molecular cloning, sequencing and functional study of the promoter region of the human alpha2C4-adrenergic receptor gene.

Q63175	SERC5_RAT	Serine incorporator 5	9326262	TPO1, a member of a novel protein family, is developmentally regulated in cultured oligodendrocytes.

O88572	LRP6_MOUSE	Low-density lipoprotein receptor-related protein 6	15142971	The Wnt co-receptors Lrp5 and Lrp6 are essential for gastrulation in mice.

O43614	OX2R_HUMAN	Orexin receptor type 2	9491897	Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior.

Q7Z1I0	CUPF_DICDI	Calcium up-regulated protein F	14871937	The Ca2+/calcineurin-regulated cup gene family in Dictyostelium discoideum and its possible involvement in development.

Q9ERQ6	CSPG5_RAT	Chondroitin sulfate proteoglycan 5	11069908	CALEB binds via its acidic stretch to the fibrinogen-like domain of tenascin-C or tenascin-R and its expression is dynamically regulated after optic nerve lesion.

P46779	RL28_HUMAN	60S ribosomal protein L28	7772601	Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs.

P25437	FRMA_ECOLI	S-(hydroxymethyl)glutathione dehydrogenase	1731906	Purification, characterization, and partial sequence of the glutathione-dependent formaldehyde dehydrogenase from Escherichia coli: a class III alcohol dehydrogenase.

Q9DBY0	FOXP4_MOUSE	Forkhead box protein P4	14701752	Transcriptional and DNA binding activity of the Foxp1/2/4 family is modulated by heterotypic and homotypic protein interactions.

Q9SJM0	CALSA_ARATH	Callose synthase 10	18315544	Dual function of Arabidopsis glucan synthase-like genes GSL8 and GSL10 in male gametophyte development and plant growth.

Q10336	MCP6_SCHPO	Meiotic coiled-coil protein 6	16111942	Hrs1p/Mcp6p on the meiotic SPB organizes astral microtubule arrays for oscillatory nuclear movement.

Q15493	RGN_HUMAN	Regucalcin	7548213	Isolation of cDNA clone encoding human homologue of senescence marker protein-30 (SMP30) and its location on the X chromosome.

Q9P3V3	YI47_SCHPO	UPF0494 membrane protein C1348.07	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P78774	ARPC1_SCHPO	Actin-related protein 2/3 complex subunit 1	8978670	Fission yeast Sop2p: a novel and evolutionarily conserved protein that interacts with Arp3p and modulates profilin function.

Q9VMW9	GMDS_DROME	GDP-mannose 4,6 dehydratase	16650000	Reconstitution in vitro of the GDP-fucose biosynthetic pathways of Caenorhabditis elegans and Drosophila melanogaster.

P07311	ACYP1_HUMAN	Acylphosphatase-1	7796909	Cloning and expression of the cDNA coding for the erythrocyte isoenzyme of human acylphosphatase.

Q07471	THI3_YEAST	Thiamine metabolism regulatory protein THI3	10753893	An investigation of the metabolism of isoleucine to active Amyl alcohol in Saccharomyces cerevisiae.

Q9Y5F2	PCDBB_HUMAN	Protocadherin beta-11	11322959	The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number.

Q6UX15	LAYN_HUMAN	Layilin	11294894	Layilin, a novel integral membrane protein, is a hyaluronan receptor.

Q8INB9	AKT1_DROME	RAC serine/threonine-protein kinase	7876156	Developmental regulation of expression and activity of multiple forms of the Drosophila RAC protein kinase.

Q5U385	TBPL1_DANRE	TATA box-binding protein-like protein 1	11250159	TBP is not universally required for zygotic RNA polymerase II transcription in zebrafish.

P48731	ATH1_ARATH	Homeobox protein ATH1	7696878	The homeobox gene ATH1 of Arabidopsis is derepressed in the photomorphogenic mutants cop1 and det1.

Q42563	APT2_ARATH	Adenine phosphoribosyltransferase 2	8696367	A second form of adenine phosphoribosyltransferase in Arabidopsis thaliana with relative specificity towards cytokinins.

Q8TDR0	MIPT3_HUMAN	TRAF3-interacting protein 1	12935900	MIP-T3 associates with IL-13Ralpha1 and suppresses STAT6 activation in response to IL-13 stimulation.

Q05924	DCR2_YEAST	Phosphatase DCR2	15590836	Gid8p (Dcr1p) and Dcr2p function in a common pathway to promote START completion in Saccharomyces cerevisiae.

Q16342	PDCD2_HUMAN	Programmed cell death protein 2	7606924	Isolation and mapping of a human gene (PDCD2) that is highly homologous to Rp8, a rat gene associated with programmed cell death.

P28519	RAD14_YEAST	DNA repair protein RAD14	8516285	Yeast DNA-repair gene RAD14 encodes a zinc metalloprotein with affinity for ultraviolet-damaged DNA.

P40037	HMF1_YEAST	Protein HMF1	11003673	Mmf1p, a novel yeast mitochondrial protein conserved throughout evolution and involved in maintenance of the mitochondrial genome.

P38992	SUR2_YEAST	Sphingolipid C4-hydroxylase SUR2	8868422	SYR2, a gene necessary for syringomycin growth inhibition of Saccharomyces cerevisiae.

Q70GP4	STATB_DICDI	Signal transducer and activator of transcription B	14701681	Dd-STATb, a Dictyostelium STAT protein with a highly aberrant SH2 domain, functions as a regulator of gene expression during growth and early development.

Q9VHA0	SCM_DROME	Polycomb protein Scm	9343432	A domain shared by the polycomb group proteins Scm and ph mediates heterotypic and homotypic interactions.

Q99PI5	LPIN2_MOUSE	Phosphatidate phosphatase LPIN2	17158099	Three mammalian lipins act as phosphatidate phosphatases with distinct tissue expression patterns.

O88846	RNF4_RAT	E3 ubiquitin ligase RNF4	9710597	Identification of a novel RING finger protein as a coregulator in steroid receptor-mediated gene transcription.

Q3KPK4	BORE1_XENLA	Borealin	17199039	Chromosomal enrichment and activation of the aurora B pathway are coupled to spatially regulate spindle assembly.

P24390	ERD21_HUMAN	ER lumen protein retaining receptor 1	2172835	A human homologue of the yeast HDEL receptor.

P42003	MAD_DROME	Protein mothers against dpp	11703946	The DSmurf ubiquitin-protein ligase restricts BMP signaling spatially and temporally during Drosophila embryogenesis.

P53552	THO2_YEAST	THO complex subunit 2	11060033	A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae.

P06780	RHO1_YEAST	GTP-binding protein RHO1	11283608	Spatial regulation of the exocyst complex by Rho1 GTPase.

P49662	CASP4_HUMAN	Caspase-4	7743998	A novel human protease similar to the interleukin-1 beta converting enzyme induces apoptosis in transfected cells.

Q9BQT8	ODC_HUMAN	Mitochondrial 2-oxodicarboxylate carrier	11083877	Identification of the human mitochondrial oxodicarboxylate carrier. Bacterial expression, reconstitution, functional characterization, tissue distribution and chromosomal location.

Q94GB1	PUP2_ARATH	Purine permease 2	10662864	A new family of high-affinity transporters for adenine, cytosine, and purine derivatives in Arabidopsis.

O13878	UTP17_SCHPO	U3 small nucleolar RNA-associated protein 17	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O95140	MFN2_HUMAN	Mitofusin-2	15322553	Dysregulation of HSG triggers vascular proliferative disorders.

P38696	ARP1_YEAST	Centractin	16291862	Arp10p is a pointed-end-associated component of yeast dynactin.

O15120	PLCB_HUMAN	1-acyl-sn-glycerol-3-phosphate acyltransferase beta	9212163	Cloning and expression of two human lysophosphatidic acid acyltransferase cDNAs that enhance cytokine-induced signaling responses in cells.

Q9JKS5	HABP4_MOUSE	Intracellular hyaluronan-binding protein 4	10887182	Molecular characterization of a novel intracellular hyaluronan- binding protein.

Q8WWQ0	PHIP_HUMAN	PH-interacting protein	11018022	Cloning and characterization of PHIP, a novel insulin receptor substrate-1 pleckstrin homology domain interacting protein.

Q03718	NSE5_YEAST	Non-structural maintenance of chromosome element 5	15738391	A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization.

Q50KB1	SEP2_EMIHU	Protein disulfide-isomerase-like protein EhSep2	15743763	A novel eukaryotic selenoprotein in the haptophyte alga Emiliania huxleyi.

Q01201	RELB_HUMAN	Transcription factor RelB	1577270	I-Rel: a novel rel-related protein that inhibits NF-kappa B transcriptional activity.

O14320	COA1_SCHPO	Cytochrome oxidase assembly protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P29375	KDM5A_HUMAN	Lysine-specific demethylase 5A	11358960	Retinoblastoma-binding protein 2 (Rbp2) potentiates nuclear hormone receptor-mediated transcription.

Q6ZNA4	RN111_HUMAN	E3 ubiquitin-protein ligase Arkadia	16601693	Axin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia.

Q01094	E2F1_HUMAN	Transcription factor E2F1	11418595	E2F transcriptional activation requires TRRAP and GCN5 cofactors.

Q9NP98	MYOZ1_HUMAN	Myozenin-1	16076904	The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins.

P08393	ICP0_HHV11	E3 ubiquitin-protein ligase ICP0	15247261	A RING finger ubiquitin ligase is protected from autocatalyzed ubiquitination and degradation by binding to ubiquitin-specific protease USP7.

Q14511	CASL_HUMAN	Enhancer of filamentation 1	9584194	Cell cycle-regulated processing of HEF1 to multiple protein forms differentially targeted to multiple subcellular compartments.

P07315	CRGC_HUMAN	Gamma-crystallin C	12507494	Homology models of human gamma-crystallins: structural study of the extensive charge network in gamma-crystallins.

P67775	PP2AA_HUMAN	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform	16580887	PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation.

O75469	NR1I2_HUMAN	Nuclear receptor subfamily 1 group I member 2	12578355	2.1 A crystal structure of human PXR in complex with the St. John's wort compound hyperforin.

P62617	ISPF_ECOLI	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	10694574	Biosynthesis of terpenoids: YgbB protein converts 4-diphosphocytidyl- 2C-methyl-D-erythritol 2-phosphate to 2C-methyl-D-erythritol 2,4- cyclodiphosphate.

Q07837	SLC31_HUMAN	Neutral and basic amino acid transport protein rBAT	11318953	Human cystinuria-related transporter: localization and functional characterization.

P53267	DAM1_YEAST	DASH complex subunit DAM1	15664196	Formation of a dynamic kinetochore-microtubule interface through assembly of the Dam1 ring complex.

P68036	UB2L3_HUMAN	Ubiquitin-conjugating enzyme E2 L3	10888878	Familial Parkinson disease gene product, parkin, is a ubiquitin- protein ligase.

Q9SUA4	OPT5_ARATH	Oligopeptide transporter 5	11788749	An oligopeptide transporter gene family in Arabidopsis.

P50528	PLO1_SCHPO	Serine/threonine-protein kinase plo1	12815070	Physical and functional interactions between polo kinase and the spindle pole component Cut12 regulate mitotic commitment in S. pombe.

P42736	RAP23_ARATH	Ethylene-responsive transcription factor RAP2-3	9192694	The AP2 domain of APETALA2 defines a large new family of DNA binding proteins in Arabidopsis.

P0AA89	DOSC_ECOLI	Diguanylate cyclase DosC	16418169	Genome-wide transcriptional profile of Escherichia coli in response to high levels of the second messenger 3',5'-cyclic diguanylic acid.

Q8WUY8	NAT14_HUMAN	N-acetyltransferase 14	10873651	Cloning of a coproporphyrinogen oxidase promoter regulatory element binding protein.

Q91848	SIAM_XENLA	Homeobox protein siamois	11291853	Siamois cooperates with TGFbeta signals to induce the complete function of the Spemann-Mangold organizer.

Q99519	NEUR1_HUMAN	Sialidase-1	8985184	Characterization of human lysosomal neuraminidase defines the molecular basis of the metabolic storage disorder sialidosis.

O74850	DGA1_SCHPO	Diacylglycerol O-acyltransferase 1	12963726	Schizosaccharomyces pombe cells deficient in triacylglycerols synthesis undergo apoptosis upon entry into the stationary phase.

P25092	GUC2C_HUMAN	Heat-stable enterotoxin receptor	1680854	Primary structure and functional expression of the human receptor for Escherichia coli heat-stable enterotoxin.

P87306	MED17_SCHPO	Mediator of RNA polymerase II transcription subunit 17	10625684	Purification and characterization of RNA polymerase II holoenzyme from Schizosaccharomyces pombe.

P30040	ERP29_HUMAN	Endoplasmic reticulum resident protein 29	9738895	ERp28, a human endoplasmic-reticulum-lumenal protein, is a member of the protein disulfide isomerase family but lacks a CXXC thioredoxin- box motif.

Q06836	SYT1_YEAST	Arf guanine nucleotide exchange factor SYT1	10430582	Genetic interactions in yeast between Ypt GTPases and Arf guanine nucleotide exchangers.

P05375	PEM2_YEAST	Methylene-fatty-acyl-phospholipid synthase	2445736	Yeast phosphatidylethanolamine methylation pathway. Cloning and characterization of two distinct methyltransferase genes.

Q70UZ7	VWA2_MOUSE	von Willebrand factor A domain-containing protein 2	14506275	Identification and characterization of AMACO, a new member of the von Willebrand factor A-like domain protein superfamily with a regulated expression in the kidney.

P17010	ZFX_HUMAN	Zinc finger X-chromosomal protein	2500252	ZFX has a gene structure similar to ZFY, the putative human sex determinant, and escapes X inactivation.

O00764	PDXK_HUMAN	Pyridoxal kinase	10987144	Human pyridoxal kinase: overexpression and properties of the recombinant enzyme.

P31335	PUR9_CHICK	Bifunctional purine biosynthesis protein PURH	11323713	Crystal structure of a bifunctional transformylase and cyclohydrolase enzyme in purine biosynthesis.

Q9NYX4	CALY_HUMAN	Neuron-specific vesicular protein calcyon	14534309	Elevated intracellular calcium triggers recruitment of the receptor cross-talk accessory protein calcyon to the plasma membrane.

P13395	SPTCA_DROME	Spectrin alpha chain	11076973	Lava lamp, a novel peripheral Golgi protein, is required for Drosophila melanogaster cellularization.

O43683	BUB1_HUMAN	Mitotic checkpoint serine/threonine-protein kinase BUB1	16760428	Phosphorylation- and polo-box-dependent binding of Plk1 to Bub1 is required for the kinetochore localization of Plk1.

Q5M834	DTBP1_RAT	Dysbindin	19428785	Direct interaction of dysbindin with the AP-3 complex via its mu subunit.

P63235	GADC_ECOLI	Probable glutamate/gamma-aminobutyrate antiporter	8682809	A glutamate-dependent acid resistance gene in Escherichia coli.

P36102	PAN3_YEAST	PAB-dependent poly(A)-specific ribonuclease subunit PAN3	14562095	Global analysis of protein localization in budding yeast.

Q13573	SNW1_HUMAN	SNW domain-containing protein 1	9632709	Isolation and characterization of a novel coactivator protein, NCoA- 62, involved in vitamin D-mediated transcription.

Q92504	S39A7_HUMAN	Zinc transporter SLC39A7	8812499	cDNA cloning of the human homologues of the mouse Ke4 and Ke6 genes at the centromeric end of the human MHC region.

Q06609	RAD51_HUMAN	DNA repair protein RAD51 homolog 1	8358431	Cloning of human, mouse and fission yeast recombination genes homologous to RAD51 and recA.

P51918	GON1_HAPBU	Progonadoliberin-1	9843638	Ontogeny of gonadotropin-releasing hormone (GnRH) gene expression reveals a distinct origin for GnRH-containing neurons in the midbrain.

Q9HGN8	SVF2_SCHPO	Survival factor 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P98193	DMP1_RAT	Dentin matrix acidic phosphoprotein 1	8509401	Characterization of a novel dentin matrix acidic phosphoprotein. Implications for induction of biomineralization.

Q9Z2B2	UCP5_MOUSE	Brain mitochondrial carrier protein 1	9852133	BMCP1, a novel mitochondrial carrier with high expression in the central nervous system of humans and rodents, and respiration uncoupling activity in recombinant yeast.

P58012	FOXL2_HUMAN	Forkhead box protein L2	11175783	The putative forkhead transcription factor FOXL2 is mutated in blepharophimosis/ptosis/epicanthus inversus syndrome.

Q06106	MRD1_YEAST	Multiple RNA-binding domain-containing protein 1	11884397	Mrd1p is required for processing of pre-rRNA and for maintenance of steady-state levels of 40 S ribosomal subunits in yeast.

Q9EPQ0	NCKX3_RAT	Sodium/potassium/calcium exchanger 3	11294880	Molecular cloning of a third member of the potassium-dependent sodium-calcium exchanger gene family, NCKX3.

Q63433	PKN1_RAT	Serine/threonine-protein kinase N1	8943281	Phosphorylation events associated with different states of activation of a hepatic cardiolipin/protease-activated protein kinase. Structural identity to the protein kinase N-type protein kinases.

Q9P5M9	MUG14_SCHPO	Meiotically up-regulated gene 14 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O75563	SKAP2_HUMAN	Src kinase-associated phosphoprotein 2	9671755	FYB (FYN binding protein) serves as a binding partner for lymphoid protein and FYN kinase substrate SKAP55 and a SKAP55-related protein in T cells.

Q9N658	GFI1_DROME	Zinc finger protein sens	11709152	senseless repression of rough is required for R8 photoreceptor differentiation in the developing Drosophila eye.

Q05513	KPCZ_HUMAN	Protein kinase C zeta type	18190796	KIBRA interacts with discoidin domain receptor 1 to modulate collagen-induced signalling.

Q9VUU5	KLHDB_DROME	Kelch-like protein diablo	16408305	Genome-wide P-element screen for Drosophila synaptogenesis mutants.

Q9WTX7	FHL5_MOUSE	Four and a half LIM domains protein 5	10086359	CBP-independent activation of CREM and CREB by the LIM-only protein ACT.

Q5QSK2	DESC4_RAT	Serine protease DESC4	15558215	Molecular cloning and characterisation of DESC4, a new transmembrane serine protease.

Q54QQ1	PHG2_DICDI	Serine/threonine-protein kinase phg2	16325504	A novel phosphatidylinositol 4,5-bisphosphate-binding domain targeting the Phg2 kinase to the membrane in Dictyostelium cells.

P11233	RALA_HUMAN	Ras-related protein Ral-A	2550440	Identification of the ral and rac1 gene products, low molecular mass GTP-binding proteins from human platelets.

Q8NHL6	LIRB1_HUMAN	Leukocyte immunoglobulin-like receptor subfamily B member 1	9285411	A novel immunoglobulin superfamily receptor for cellular and viral MHC class I molecules.

P43120	HHEX_MOUSE	Hematopoietically-expressed homeobox protein Hhex	10804173	Hex is a transcriptional repressor that contributes to anterior identity and suppresses Spemann organiser function.

Q9NPJ6	MED4_HUMAN	Mediator of RNA polymerase II transcription subunit 4	10235266	Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex.

Q8L925	CRC_ARATH	Protein CRABS CLAW	10225998	CRABS CLAW, a gene that regulates carpel and nectary development in Arabidopsis, encodes a novel protein with zinc finger and helix-loop- helix domains.

P36423	THAS_MOUSE	Thromboxane-A synthase	7688225	Molecular cloning and expression of murine thromboxane synthase.

Q03834	MSH6_YEAST	DNA mismatch repair protein MSH6	11237611	MSH-MLH complexes formed at a DNA mismatch are disrupted by the PCNA sliding clamp.

O94661	GYP10_SCHPO	GTPase-activating protein gyp10	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q27324	RYK1_DROME	Tyrosine-protein kinase Drl	7603568	Control of neuronal pathway selection by a Drosophila receptor protein-tyrosine kinase family member.

Q42191	OXA1_ARATH	Mitochondrial inner membrane protein OXA1	11148275	Mitochondrial localization of AtOXA1, an Arabidopsis homologue of yeast Oxa1p involved in the insertion and assembly of protein complexes in mitochondrial inner membrane.

Q8QHJ9	I17RD_DANRE	Interleukin-17 receptor D	11802165	Sef is a feedback-induced antagonist of Ras/MAPK-mediated FGF signalling.

P38632	NSE2_YEAST	E3 SUMO-protein ligase MMS21	14562095	Global analysis of protein localization in budding yeast.

O14462	SEC4_CANAL	Ras-related protein SEC4	10572126	Overexpression of a dominant-negative allele of SEC4 inhibits growth and protein secretion in Candida albicans.

Q92351	PCP1_SCHPO	Spindle pole body protein pcp1	15546621	An SMC-domain protein in fission yeast links telomeres to the meiotic centrosome.

Q9M9E1	AB40G_ARATH	ABC transporter G family member 40	16506311	Organization and function of the plant pleiotropic drug resistance ABC transporter family.

Q05979	KYNU_YEAST	Kynureninase	14562095	Global analysis of protein localization in budding yeast.

Q03323	SDC1_YEAST	COMPASS component SDC1	11742990	The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4.

O35820	RCL_RAT	Deoxyribonucleoside 5'-monophosphate N-glycosidase	17234634	The c-Myc target gene Rcl (C6orf108) encodes a novel enzyme, deoxynucleoside 5'-monophosphate N-glycosidase.

Q62418	DBNL_MOUSE	Drebrin-like protein	12913069	Fgd1, the Cdc42 GEF responsible for faciogenital dysplasia, directly interacts with cortactin and mAbp1 to modulate cell shape.

Q92563	TICN2_HUMAN	Testican-2	10386950	Molecular cloning of testican-2: defining a novel calcium-binding proteoglycan family expressed in brain.

Q96524	CRY2_ARATH	Cryptochrome-2	17470059	Light-regulated large-scale reorganization of chromatin during the floral transition in Arabidopsis.

P32771	FADH_YEAST	S-(hydroxymethyl)glutathione dehydrogenase	8483449	Molecular structure and genetic regulation of SFA, a gene responsible for resistance to formaldehyde in Saccharomyces cerevisiae, and characterization of its protein product.

P34164	SIP2_YEAST	SNF1 protein kinase subunit beta-2	12562756	Sip2, an N-myristoylated beta subunit of Snf1 kinase, regulates aging in Saccharomyces cerevisiae by affecting cellular histone kinase activity, recombination at rDNA loci, and silencing.

Q9VTI8	CHRB_DROME	Protein charybde	16423342	scylla and charybde, homologues of the human apoptotic gene RTP801, are required for head involution in Drosophila.

Q8IRW8	TRR_DROME	Histone-lysine N-methyltransferase trr	14603321	Methylation at lysine 4 of histone H3 in ecdysone-dependent development of Drosophila.

P51807	DYLT1_MOUSE	Dynein light chain Tctex-type 1	19448628	Lfc and Tctex-1 regulate the genesis of neurons from cortical precursor cells.

P18065	IBP2_HUMAN	Insulin-like growth factor-binding protein 2	19081843	Duplication of the IGFBP-2 gene in teleost fish: protein structure and functionality conservation and gene expression divergence.

P27105	STOM_HUMAN	Erythrocyte band 7 integral membrane protein	12130500	Stomatin is a major lipid-raft component of platelet alpha granules.

Q80VJ6	ZSC4C_MOUSE	Zinc finger and SCAN domain containing protein 4C	20336070	Zscan4 regulates telomere elongation and genomic stability in ES cells.

Q13616	CUL1_HUMAN	Cullin-1	16880511	Regulation of p27 degradation and S-phase progression by Ro52 RING finger protein.

P28005	POP5_YEAST	Ribonucleases P/MRP protein subunit POP5	9620854	Purification and characterization of the nuclear RNase P holoenzyme complex reveals extensive subunit overlap with RNase MRP.

P43554	SWP82_YEAST	SWI/SNF global transcription activator complex subunit SWP82	16204215	The RSC chromatin remodeling complex bears an essential fungal- specific protein module with broad functional roles.

Q9US00	AMT2_SCHPO	Ammonium transporter 2	16999738	Ammonium transporter genes in the fission yeast Schizosaccharomyces pombe: role in ammonium uptake and a morphological transition.

P23721	SERC_ECOLI	Phosphoserine aminotransferase	2121717	Metabolic relationships between pyridoxine (vitamin B6) and serine biosynthesis in Escherichia coli K-12.

P0C869	PA24B_HUMAN	Cytosolic phospholipase A2 beta	10085124	Molecular cloning of two new human paralogs of 85-kDa cytosolic phospholipase A2.

Q63618	ESPN_RAT	Espin	12598619	Novel espin actin-bundling proteins are localized to Purkinje cell dendritic spines and bind the Src homology 3 adapter protein insulin receptor substrate p53.

O60186	RT10_SCHPO	40S ribosomal protein S10, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O43427	FIBP_HUMAN	Acidic fibroblast growth factor intracellular-binding protein	9806903	Cloning of an intracellular protein that binds selectively to mitogenic acidic fibroblast growth factor.

Q9Y272	RASD1_HUMAN	Dexamethasone-induced Ras-related protein 1	10673050	Cloning, expression and characterization of a novel human Ras-related protein that is regulated by glucocorticoid hormone.

Q9QXX0	JAG1_MOUSE	Protein jagged-1	10551863	Mouse Jagged1 physically interacts with Notch2 and other Notch receptors: assessment by quantitative methods.

Q42524	4CL1_ARATH	4-coumarate--CoA ligase 1	10417722	Three 4-coumarate:coenzyme A ligases in Arabidopsis thaliana represent two evolutionarily divergent classes in angiosperms.

P40487	DPH1_YEAST	Diphthamide biosynthesis protein 1	15485916	Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2.

O14310	NP106_SCHPO	Nucleoporin npp106	9372936	Npp106p, a Schizosaccharomyces pombe homologue of Saccharomyces cerevisiae Nic96p, functionally interacts with Rae1p in mRNA export.

Q9BV79	MECR_HUMAN	Trans-2-enoyl-CoA reductase, mitochondrial	12654921	Characterization of 2-enoyl thioester reductase from mammals: an ortholog of Ybr026p/Mrf1'p of the yeast mitochondrial fatty acid synthesis type II.

Q08921	TCO89_YEAST	Target of rapamycin complex 1 subunit TCO89	14562095	Global analysis of protein localization in budding yeast.

P22289	QCR9_YEAST	Cytochrome b-c1 complex subunit 9	10873857	Structure at 2.3 A resolution of the cytochrome bc1 complex from the yeast Saccharomyces cerevisiae co-crystallized with an antibody Fv fragment.

P32639	BRR2_YEAST	Pre-mRNA-splicing helicase BRR2	8670905	The HeLa 200 kDa U5 snRNP-specific protein and its homologue in Saccharomyces cerevisiae are members of the DEXH-box protein family of putative RNA helicases.

P53259	PCP1_YEAST	Rhomboid protein 1, mitochondrial	12417197	A novel two-step mechanism for removal of a mitochondrial signal sequence involves the mAAA complex and the putative rhomboid protease Pcp1.

P25023	BKRB2_RAT	B2 bradykinin receptor	1715575	Expression cloning of a rat B2 bradykinin receptor.

Q9MAG8	PPR79_ARATH	Putative pentatricopeptide repeat-containing protein At1g53330	17028967	Isolation and characterization of a novel semi-lethal Arabidopsis thaliana mutant of gene for pentatricopeptide (PPR) repeat-containing protein.

P12969	IAPP_RAT	Islet amyloid polypeptide	2668946	Conservation of the sequence of islet amyloid polypeptide in five mammals is consistent with its putative role as an islet hormone.

O15381	NVL_HUMAN	Nuclear valosin-containing protein-like	9286697	NVL: a new member of the AAA family of ATPases localized to the nucleus.

Q9JHC9	ELF2_MOUSE	ETS-related transcription factor Elf-2	9001422	Elf-2, a rhombotin-2 binding ets transcription factor: discovery and potential role in T cell leukemia.

Q9H6Z4	RANB3_HUMAN	Ran-binding protein 3	9637251	Human RanBP3, a group of nuclear RanGTP binding proteins.

Q7KZN9	COX15_HUMAN	Cytochrome c oxidase assembly protein COX15 homolog	12474143	Mutations in COX15 produce a defect in the mitochondrial heme biosynthetic pathway, causing early-onset fatal hypertrophic cardiomyopathy.

Q8VEJ9	VPS4A_MOUSE	Vacuolar protein sorting-associated protein 4A	12594041	Comparative sequence and expression analyses of four mammalian VPS4 genes.

Q9SLG2	GGPP4_ARATH	Geranylgeranyl pyrophosphate synthase 4	10759500	Five geranylgeranyl diphosphate synthases expressed in different organs are localized into three subcellular compartments in Arabidopsis.

Q9Y576	ASB1_HUMAN	Ankyrin repeat and SOCS box protein 1	11111040	Cloning and characterization of the genes encoding the ankyrin repeat and SOCS box-containing proteins Asb-1, Asb-2, Asb-3 and Asb-4.

O15061	SYNEM_HUMAN	Synemin	11737198	Human synemin gene generates splice variants encoding two distinct intermediate filament proteins.

P17038	ZNF43_HUMAN	Zinc finger protein 43	1711675	A gene encoding 22 highly related zinc fingers is expressed in lymphoid cell lines.

P43292	SRK2G_ARATH	Serine/threonine-protein kinase SRK2G	8393717	Two putative protein kinases from Arabidopsis thaliana contain highly acidic domains.

O17528	TMED2_CAEEL	Suppressor/enhancer of lin-12 protein 9	10366590	p24 proteins and quality control of LIN-12 and GLP-1 trafficking in Caenorhabditis elegans.

Q4KMM3	OXR1_MOUSE	Oxidation resistance protein 1	11237729	C7, a novel nucleolar protein, is the mouse homologue of the Drosophila late puff product L82 and an isoform of human OXR1.

P03406	NEF_HV1BR	Protein Nef	11298454	HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell.

Q91WS0	CISD1_MOUSE	CDGSH iron-sulfur domain-containing protein 1	17376863	MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity.

P51681	CCR5_HUMAN	C-C chemokine receptor type 5	8639485	Molecular cloning and functional expression of a new human CC- chemokine receptor gene.

P28272	PYRD_YEAST	Dihydroorotate dehydrogenase	1511880	Nucleotide sequence of the URA1 gene of Saccharomyces cerevisiae.

P00966	ASSY_HUMAN	Argininosuccinate synthase	6194510	Sequence for human argininosuccinate synthetase cDNA.

Q9JMB7	PIWL1_MOUSE	Piwi-like protein 1	16751776	A germline-specific class of small RNAs binds mammalian Piwi proteins.

Q9K5J6	RPSB_BACAN	RNA polymerase sigma-B factor	10960085	Characterization of the operon encoding the alternative sigma(B) factor from Bacillus anthracis and its role in virulence.

O09210	BXRB_AGRCO	Bombyxin-related peptide B	8673077	Bombyxin-related peptides: cDNA structure and expression in the brain of the hornworm Agrius convolvuli.

Q0Z8B6	HJM79_ENTHR	Bacteriocin hiracin-JM79	17326750	Amino acid and nucleotide sequence, adjacent genes, and heterologous expression of hiracin JM79, a sec-dependent bacteriocin produced by Enterococcus hirae DCH5, isolated from Mallard ducks (Anas platyrhynchos).

Q67YU0	CKX5_ARATH	Cytokinin dehydrogenase 5	12721786	Structure and function of cytokinin oxidase/dehydrogenase genes of maize, rice, Arabidopsis and other species.

P15382	KCNE1_HUMAN	Potassium voltage-gated channel subfamily E member 1	9445165	Mutation of the gene for IsK associated with both Jervell and Lange- Nielsen and Romano-Ward forms of Long-QT syndrome.

P38398	BRCA1_HUMAN	Breast cancer type 1 susceptibility protein	19261748	MERIT40 facilitates BRCA1 localization and DNA damage repair.

O60500	NPHN_HUMAN	Nephrin	9660941	Positionally cloned gene for a novel glomerular protein -- nephrin -- is mutated in congenital nephrotic syndrome.

Q9LKI5	XPF_ARATH	DNA repair endonuclease UVH1	11826311	Repair of damaged DNA by Arabidopsis cell extract.

Q04087	LRS4_YEAST	Monopolin complex subunit LRS4	10082585	A genetic screen for ribosomal DNA silencing defects identifies multiple DNA replication and chromatin-modulating factors.

Q1JQ73	ELV1A_XENLA	ELAV-like protein 1-A	17355986	ElrA binding to the 3'UTR of cyclin E1 mRNA requires polyadenylation elements.

P31652	SC6A4_RAT	Sodium-dependent serotonin transporter	11709063	Regulation of the serotonin transporter by interacting proteins.

Q9HB71	CYBP_HUMAN	Calcyclin-binding protein	16085652	Structural analysis of Siah1-Siah-interacting protein interactions and insights into the assembly of an E3 ligase multiprotein complex.

Q96EB1	ELP4_HUMAN	Elongator complex protein 4	11714725	Purification and characterization of the human elongator complex.

Q9LKZ3	RBR1_ARATH	Retinoblastoma-related protein 1	18064404	Arabidopsis RETINOBLASTOMA-RELATED PROTEIN 1 is involved in G1 phase cell cycle arrest caused by sucrose starvation.

Q9JJZ8	CNGA3_MOUSE	Cyclic nucleotide-gated cation channel alpha-3	10662822	Molecular cloning and functional characterization of a new modulatory cyclic nucleotide-gated channel subunit from mouse retina.

Q8C5W0	CLMN_MOUSE	Calmin	11386753	Calmin, a protein with calponin homology and transmembrane domains expressed in maturing spermatogenic cells.

Q13428	TCOF_HUMAN	Treacle protein	9096354	TCOF1 gene encodes a putative nucleolar phosphoprotein that exhibits mutations in Treacher Collins syndrome throughout its coding region.

P10674	FAS1_DROME	Fasciclin-1	2394715	Drosophila fasciclin I, a neural cell adhesion molecule, has a phosphatidylinositol lipid membrane anchor that is developmentally regulated.

Q9JKT4	TR105_MOUSE	Taste receptor type 2 member 105	10761934	A novel family of mammalian taste receptors.

P54115	ALDH6_YEAST	Magnesium-activated aldehyde dehydrogenase, cytosolic	9392076	The ALD6 gene of Saccharomyces cerevisiae encodes a cytosolic, Mg(2+)-activated acetaldehyde dehydrogenase.

Q9Y2D8	ADIP_HUMAN	Afadin- and alpha-actinin-binding protein	12007189	The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP.

P84087	CPLX2_RAT	Complexin-2	11751907	Rapid and selective binding to the synaptic SNARE complex suggests a modulatory role of complexins in neuroexocytosis.

Q12385	ICT1_YEAST	1-acylglycerol-3-phosphate O-acyltransferase ICT1	18252723	YLR099C (ICT1) encodes a soluble Acyl-CoA-dependent lysophosphatidic acid acyltransferase responsible for enhanced phospholipid synthesis on organic solvent stress in Saccharomyces cerevisiae.

Q9Y297	FBW1A_HUMAN	F-box/WD repeat-containing protein 1A	9859996	Identification of the receptor component of the IkappaBalpha- ubiquitin ligase.

Q8C767	PPR3B_MOUSE	Protein phosphatase 1 regulatory subunit 3B	11872655	Human skeletal muscle expresses a glycogen-targeting subunit of PP1 that is identical to the insulin-sensitive glycogen-targeting subunit G(L) of liver.

Q9UTS6	DYLT_SCHPO	Dynein light chain Tctex-type	11907273	The 14-kDa dynein light chain-family protein Dlc1 is required for regular oscillatory nuclear movement and efficient recombination during meiotic prophase in fission yeast.

Q08683	APC5_YEAST	Anaphase-promoting complex subunit 5	9469814	Mass spectrometric analysis of the anaphase-promoting complex from yeast: identification of a subunit related to cullins.

O14556	G3PT_HUMAN	Glyceraldehyde-3-phosphate dehydrogenase, testis-specific	10714828	Human glyceraldehyde 3-phosphate dehydrogenase-2 gene is expressed specifically in spermatogenic cells.

Q9QZE9	T150A_RAT	Transmembrane protein 150A	10858565	Identification of a new gene (rat TM6P1) encoding a fasting- inducible, integral membrane protein with six transmembrane domains.

Q9ES00	UBE4B_MOUSE	Ubiquitin conjugation factor E4 B	12504083	Characterization of the mouse gene for the U-box-type ubiquitin ligase UFD2a.

Q99816	TS101_HUMAN	Tumor susceptibility gene 101 protein	17229889	Spongiform neurodegeneration-associated E3 ligase Mahogunin ubiquitylates TSG101 and regulates endosomal trafficking.

P80299	HYES_RAT	Epoxide hydrolase 2	8349641	Isolation and characterization of a cDNA encoding rat liver cytosolic epoxide hydrolase and its functional expression in Escherichia coli.

Q940X7	RBX1A_ARATH	RING-box protein 1a	12682009	The RUB/Nedd8 conjugation pathway is required for early development in Arabidopsis.

Q42479	CDPK3_ARATH	Calcium-dependent protein kinase 3	17032064	CDPKs CPK6 and CPK3 function in ABA regulation of guard cell S-type anion-and Ca(2+)-permeable channels and stomatal closure.

P38915	SPT8_YEAST	Transcription factor SPT8	9674426	A subset of TAF(II)s are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulation.

P22897	MRC1_HUMAN	Macrophage mannose receptor 1	1294118	Organization of the gene encoding the human macrophage mannose receptor (MRC1).

P32870	CYA1_DROME	Ca(2+)/calmodulin-responsive adenylate cyclase	1739965	The Drosophila learning and memory gene rutabaga encodes a Ca2+/Calmodulin-responsive adenylyl cyclase.

P0AEC8	DCUS_ECOLI	Sensor protein dcuS	12167640	Function of DcuS from Escherichia coli as a fumarate-stimulated histidine protein kinase in vitro.

Q6PI98	IN80C_HUMAN	INO80 complex subunit C	15960975	Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

Q12906	ILF3_HUMAN	Interleukin enhancer-binding factor 3	9442054	DNA-dependent protein kinase interacts with antigen receptor response element binding proteins NF90 and NF45.

Q7TQB0	TR134_MOUSE	Taste receptor type 2 member 134	12734386	Evolutionary relationships of the Tas2r receptor gene families in mouse and human.

P22626	ROA2_HUMAN	Heterogeneous nuclear ribonucleoproteins A2/B1	7789969	Structure and expression of the gene (HNRPA2B1) encoding the human hnRNP protein A2/B1.

P38169	KMO_YEAST	Kynurenine 3-monooxygenase	12062417	Aerobic and anaerobic NAD+ metabolism in Saccharomyces cerevisiae.

Q6NY15	TSG10_MOUSE	Testis-specific gene 10 protein	16643851	Expression of Tsga10 sperm tail protein in embryogenesis and neural development: from cilium to cell division.

P48552	NRIP1_HUMAN	Nuclear receptor-interacting protein 1	7641693	Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor.

Q9YGK8	IRX1A_XENLA	Iroquois-class homeodomain protein irx-1-A	11747072	Xiro-1 controls mesoderm patterning by repressing bmp-4 expression in the Spemann organizer.

O22161	ADLO1_ARATH	Protein ARABIDILLO 1	19962994	PAH-domain-specific interactions of the Arabidopsis transcription coregulator SIN3-LIKE1 (SNL1) with telomere-binding protein 1 and ALWAYS EARLY2 Myb-DNA binding factors.

P18014	IPA7_SHIFL	Probable E3 ubiquitin-protein ligase ipaH7.8	11418613	Shigella protein IpaH(9.8) is secreted from bacteria within mammalian cells and transported to the nucleus.

P39984	HAT2_YEAST	Histone acetyltransferase type B subunit 2	9575221	HAT1 and HAT2 proteins are components of a yeast nuclear histone acetyltransferase enzyme specific for free histone H4.

Q9UTA4	POPI_SCHPO	Ribonucleases P/MRP protein subunit pop1	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

Q12412	PNS1_YEAST	Protein PNS1	15002745	Reexamining the role of choline transporter-like (Ctlp) proteins in choline transport.

O74472	MUG33_SCHPO	Meiotically up-regulated gene 33 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P43403	ZAP70_HUMAN	Tyrosine-protein kinase ZAP-70	1423621	ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain.

O14322	MU100_SCHPO	Meiotically up-regulated gene 100 protein, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P84840	ES1_RANSA	Esculentin-1	16394170	Skin secretions of Rana saharica frogs reveal antimicrobial peptides esculentins-1 and -1B and brevinins-1E and -2EC with novel insulin releasing activity.

Q04934	IVY1_YEAST	Protein IVY1	12553664	A novel phospholipid-binding protein from the yeast Saccharomyces cerevisiae with dual binding specificities for the transport GTPase Ypt7p and the Sec1-related Vps33p.

P41991	PES10_CAEEL	Patterned expression site protein 10	7607073	Soma-germline asymmetry in the distributions of embryonic RNAs in Caenorhabditis elegans.

Q03013	GSTM4_HUMAN	Glutathione S-transferase Mu 4	8349586	Isolation and analysis of the gene and cDNA for a human Mu class glutathione S-transferase, GSTM4.

Q96LR5	UB2E2_HUMAN	Ubiquitin-conjugating enzyme E2 E2	20061386	The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.

Q99867	TBB4Q_HUMAN	Putative tubulin beta-4q chain	10828619	Identification of a novel beta-tubulin subfamily with one member (TUBB4Q) located near the telomere of chromosome region 4q35.

P25705	ATPA_HUMAN	ATP synthase subunit alpha, mitochondrial	11410595	Atp11p and Atp12p are assembly factors for the F(1)-ATPase in human mitochondria.

Q92902	HPS1_HUMAN	Hermansky-Pudlak syndrome 1 protein	8896559	Positional cloning of a gene for Hermansky-Pudlak syndrome, a disorder of cytoplasmic organelles.

P46019	KPB2_HUMAN	Phosphorylase b kinase regulatory subunit alpha, liver isoform	7549948	Isolation of cDNA encoding the human liver phosphorylase kinase alpha subunit (PHKA2) and identification of a missense mutation of the PHKA2 gene in a family with liver phosphorylase kinase deficiency.

Q24940	CATLL_FASHE	Cathepsin L-like proteinase	8192668	The secreted cathepsin L-like proteinases of the trematode Fasciola hepatica, contain 3-hydroxyproline residues.

P38700	APM2_YEAST	Adaptin medium chain homolog APM2	10564262	Adaptor complex-independent clathrin function in yeast.

Q04206	TF65_HUMAN	Transcription factor p65	11931769	The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1.

Q8VBV7	CSN8_MOUSE	COP9 signalosome complex subunit 8	9707402	The COP9 complex is conserved between plants and mammals and is related to the 26S proteasome regulatory complex.

Q9USM1	ADRM1_SCHPO	Probable proteasomal ubiquitin receptor ADRM1 homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q54I36	PYK3_DICDI	Dual specificity protein kinase pyk3	18657170	Dictyostelium kinase DPYK3 negatively regulates STATc signaling in cell fate decision.

P53956	YNE6_YEAST	Uncharacterized endoplasmic reticulum membrane protein YNL046W	14562095	Global analysis of protein localization in budding yeast.

Q6DE08	AUKBA_XENLA	Serine/threonine-protein kinase 12-A	15260989	The chromosomal passenger complex is required for chromatin-induced microtubule stabilization and spindle assembly.

P83434	NLTP1_PHAAU	Non-specific lipid-transfer protein 1	15823028	Characterization and structural analyses of nonspecific lipid transfer protein 1 from mung bean.

P32504	CBF3A_YEAST	Centromere DNA-binding protein complex CBF3 subunit A	8486732	NDC10: a gene involved in chromosome segregation in Saccharomyces cerevisiae.

Q8QZX5	LSM10_MOUSE	U7 snRNA-associated Sm-like protein LSm10	19470752	Three proteins of the U7-specific Sm ring function as the molecular ruler to determine the site of 3'-end processing in mammalian histone pre-mRNA.

Q7Z6Z7	HUWE1_HUMAN	E3 ubiquitin-protein ligase HUWE1	15989957	Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis.

Q13886	KLF9_HUMAN	Krueppel-like factor 9	8051167	Cell-specific translational control of transcription factor BTEB expression. The role of an upstream AUG in the 5'-untranslated region.

Q9ESK9	RBCC1_MOUSE	RB1-inducible coiled-coil protein 1	19258318	ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy.

A1YKT1	TCP18_ARATH	Transcription factor TCP18	17307924	Arabidopsis BRANCHED1 acts as an integrator of branching signals within axillary buds.

Q9V9K7	SRRT_DROME	Serrate RNA effector molecule homolog	19632183	Ars2 regulates both miRNA- and siRNA- dependent silencing and suppresses RNA virus infection in Drosophila.

Q9UN76	S6A14_HUMAN	Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)	10446133	Cloning and functional expression of a human Na(+) and Cl(-)- dependent neutral and cationic amino acid transporter B(0+).

O22476	BRI1_ARATH	Protein BRASSINOSTEROID INSENSITIVE 1	9298904	A putative leucine-rich repeat receptor kinase involved in brassinosteroid signal transduction.

Q6P1X5	TAF2_HUMAN	Transcription initiation factor TFIID subunit 2	9774672	Novel cofactors and TFIIA mediate functional core promoter selectivity by the human TAFII150-containing TFIID complex.

O94566	MU184_SCHPO	Meiotically up-regulated gene 184 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P00937	TRPG_YEAST	Anthranilate synthase component 2	6323449	Nucleotide sequence of Saccharomyces cerevisiae genes TRP2 and TRP3 encoding bifunctional anthranilate synthase: indole-3-glycerol phosphate synthase.

P13134	KEX2_YEAST	Kexin	2646633	Yeast prohormone processing enzyme (KEX2 gene product) is a Ca2+- dependent serine protease.

Q9NXV6	CARF_HUMAN	CDKN2A-interacting protein	15109303	Alternative reading frame protein (ARF)-independent function of CARF (collaborator of ARF) involves its interactions with p53: evidence for a novel p53-activation pathway and its negative feedback control.

Q9GZP8	IMUP_HUMAN	Immortalization up-regulated protein	11606055	Identification of hepatocyte growth factor activator inhibitor type 2 (HAI-2)-related small peptide (H2RSP): its nuclear localization and generation of chimeric mRNA transcribed from both HAI-2 and H2RSP genes.

A3E7Z6	DLYKI_COHLA	D-lyxose ketol-isomerase	17189362	Characterization of a novel D-lyxose isomerase from Cohnella laevoribosii RI-39 sp. nov.

Q9JI93	A4GAT_RAT	Lactosylceramide 4-alpha-galactosyltransferase	10854428	Cloning of Gb3 synthase, the key enzyme in globo-series glycosphingolipid synthesis, predicts a family of alpha1,4- glycosyltransferases conserved in plants, insects and mammals.

P04785	PDIA1_RAT	Protein disulfide-isomerase	2841089	Enzyme binding-inhibiting assay for iodothyronine 5'-monodeiodinase (5'-MD) and its application to isolation of complementary deoxyribonucleic acid clones for the 5'-MD in rat liver.

Q9NRA0	SPHK2_HUMAN	Sphingosine kinase 2	10751414	Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform.

P51659	DHB4_HUMAN	Peroxisomal multifunctional enzyme type 2	7487879	Molecular cloning of a novel widely expressed human 80 kDa 17 beta- hydroxysteroid dehydrogenase IV.

P0ADC6	LPTG_ECOLI	Lipopolysaccharide export system permease protein lptG	18375759	Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.

O13787	SEC62_SCHPO	Translocation protein sec62	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P13497	BMP1_HUMAN	Bone morphogenetic protein 1	7798260	Bone morphogenetic protein-1 and a mammalian tolloid homologue (mTld) are encoded by alternatively spliced transcripts which are differentially expressed in some tissues.

Q9Y3M2	CBY1_HUMAN	Protein chibby homolog 1	15194699	PIGEA-14, a novel coiled-coil protein affecting the intracellular distribution of polycystin-2.

P97930	KTHY_MOUSE	Thymidylate kinase	8845311	Molecular characterization of the murine thymidylate kinase gene.

Q2NKI2	VAX1_MOUSE	Ventral anterior homeobox 1	10601035	The homeodomain protein vax1 is required for axon guidance and major tract formation in the developing forebrain.

O15205	UBD_HUMAN	Ubiquitin D	15831455	FAT10, a ubiquitin-independent signal for proteasomal degradation.

P43609	RSC8_YEAST	Chromatin structure-remodeling complex protein RSC8	12183366	Chromatin remodeling by RSC involves ATP-dependent DNA translocation.

O00213	APBB1_HUMAN	Amyloid beta A4 precursor protein-binding family B member 1	18468999	Regulation of FE65 nuclear translocation and function by amyloid beta-protein precursor in osmotically stressed cells.

P13350	CCNB1_XENLA	G2/mitotic-specific cyclin-B1	10465793	A novel p34cdc2 binding and activating protein that is necessary and sufficient to trigger G2/M progression in Xenopus oocytes.

Q04725	TLE2_HUMAN	Transducin-like enhancer protein 2	1303260	Human homologs of a Drosophila enhancer of split gene product define a novel family of nuclear proteins.

Q946J8	LHP1_ARATH	Chromo domain-containing protein LHP1	16682972	Epigenetic maintenance of the vernalized state in Arabidopsis thaliana requires LIKE HETEROCHROMATIN PROTEIN 1.

P53140	RMD9_YEAST	Protein RMD9, mitochondrial	17194786	Translation initiation in Saccharomyces cerevisiae mitochondria: functional interactions among mitochondrial ribosomal protein Rsm28p, initiation factor 2, methionyl-tRNA-formyltransferase and novel protein Rmd9p.

Q3UZ09	C1RL_MOUSE	Complement C1r subcomponent-like protein	12686506	A novel murine complement-related gene encoding a C1r-like serum protein.

Q9SWI1	PKS1_ARATH	Protein PHYTOCHROME KINASE SUBSTRATE 1	18024556	PHYTOCHROME KINASE SUBSTRATE1 regulates root phototropism and gravitropism.

P33274	CP4F1_RAT	Cytochrome P450 4F1	11980497	Covalent attachment of the heme prosthetic group in the CYP4F cytochrome P450 family.

Q5EBJ4	ERMIN_MOUSE	Ermin	16421295	Ermin, a myelinating oligodendrocyte-specific protein that regulates cell morphology.

Q9LJ45	CCU11_ARATH	Cyclin-U1-1	15197472	Molecular characterization of Arabidopsis PHO80-like proteins, a novel class of CDKA;1-interacting cyclins.

Q9JKN6	NOVA1_MOUSE	RNA-binding protein Nova-1	10719891	Nova-1 regulates neuron-specific alternative splicing and is essential for neuronal viability.

O15304	SIVA_HUMAN	Apoptosis regulatory protein Siva	12011449	Siva-1 binds to and inhibits BCL-X(L)-mediated protection against UV radiation-induced apoptosis.

Q76NV5	HPPD_DICDI	4-hydroxyphenylpyruvate dioxygenase	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

Q95ST2	WLS_DROME	Protein wntless	18193032	Wingless secretion promotes and requires retromer-dependent cycling of Wntless.

Q9H329	E41LB_HUMAN	Band 4.1-like protein 4B	10783258	Molecular cloning of a novel NF2/ERM/4.1 superfamily gene, Ehm2, that is expressed in high-metastatic K1735 murine melanoma cells.

O14757	CHK1_HUMAN	Serine/threonine-protein kinase Chk1	15798197	Coupling of human circadian and cell cycles by the timeless protein.

Q9Z238	CCNE2_MOUSE	G1/S-specific cyclin-E2	9840927	Cyclin E2: a novel CDK2 partner in the late G1 and S phases of the mammalian cell cycle.

Q9P6R2	YOH8_SCHPO	Uncharacterized protein C13E7.08c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P03891	NU2M_HUMAN	NADH-ubiquinone oxidoreductase chain 2	3921850	Six unidentified reading frames of human mitochondrial DNA encode components of the respiratory-chain NADH dehydrogenase.

Q3E790	TSC3_YEAST	Serine palmitoyltransferase-regulating protein TSC3	20182505	Orm family proteins mediate sphingolipid homeostasis.

P20936	RASA1_HUMAN	Ras GTPase-activating protein 1	8618896	Phosphotyrosine-independent binding of a 62-kDa protein to the src homology 2 (SH2) domain of p56lck and its regulation by phosphorylation of Ser-59 in the lck unique N-terminal region.

Q13541	4EBP1_HUMAN	Eukaryotic translation initiation factor 4E-binding protein 1	17368478	Structures of the human eIF4E homologous protein, h4EHP, in its m7GTP-bound and unliganded forms.

Q9UNL4	ING4_HUMAN	Inhibitor of growth protein 4	15251430	ING4 induces G2/M cell cycle arrest and enhances the chemosensitivity to DNA-damage agents in HepG2 cells.

O00418	EF2K_HUMAN	Eukaryotic elongation factor 2 kinase	9144159	Identification of a new class of protein kinases represented by eukaryotic elongation factor-2 kinase.

P75987	IRAM_ECOLI	Anti-adapter protein iraM	18383615	Multiple pathways for regulation of sigmaS (RpoS) stability in Escherichia coli via the action of multiple anti-adaptors.

Q9JHE4	G3ST1_MOUSE	Galactosylceramide sulfotransferase	10727929	cDNA cloning, genomic cloning, and tissue-specific regulation of mouse cerebroside sulfotransferase.

P04046	PUR1_YEAST	Amidophosphoribosyltransferase	6376509	Glutamine nucleotide sequence of Saccharomyces cerevisiae ADE4 encoding phosphoribosylpyrophosphate amidotransferase.

Q9CQL7	MOFA1_MOUSE	MORF4 family-associated protein 1	15367658	PAM14, a novel MRG- and Rb-associated protein, is not required for development and T-cell function in mice.

Q9D7Z6	CLCA1_MOUSE	Calcium-activated chloride channel regulator 1	12019299	The murine mCLCA3 (alias gob-5) protein is located in the mucin granule membranes of intestinal, respiratory, and uterine goblet cells.

P62273	RS29_HUMAN	40S ribosomal protein S29	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

Q9WV48	SHAN1_RAT	SH3 and multiple ankyrin repeat domains protein 1	10958799	The G protein-coupled receptor CL1 interacts directly with proteins of the Shank family.

P17141	ZFP37_MOUSE	Zinc finger protein 37	8660973	Zfp-37 is a member of the KRAB zinc finger gene family and is expressed in neurons of the developing and adult CNS.

Q9SU14	NUDT7_ARATH	Nudix hydrolase 7	16531493	Salicylic acid-independent ENHANCED DISEASE SUSCEPTIBILITY1 signaling in Arabidopsis immunity and cell death is regulated by the monooxygenase FMO1 and the Nudix hydrolase NUDT7.

Q810B7	SLIK5_MOUSE	SLIT and NTRK-like protein 5	14550773	Identification and characterization of Slitrk, a novel neuronal transmembrane protein family controlling neurite outgrowth.

Q24478	CP190_DROME	Centrosome-associated zinc finger protein CP190	8586650	The 190 kDa centrosome-associated protein of Drosophila melanogaster contains four zinc finger motifs and binds to specific sites on polytene chromosomes.

P55926	ACCN2_RAT	Amiloride-sensitive cation channel 2, neuronal	9707631	A sensory neuron-specific, proton-gated ion channel.

P07205	PGK2_HUMAN	Phosphoglycerate kinase 2	3453121	Human testis-specific PGK gene lacks introns and possesses characteristics of a processed gene.

Q8INB9	AKT1_DROME	RAC serine/threonine-protein kinase	11740943	Regulation of Drosophila tracheal system development by protein kinase B.

P53196	RPN14_YEAST	26S proteasome regulatory subunit RPN14	19446322	Multiple assembly chaperones govern biogenesis of the proteasome regulatory particle base.

P27169	PON1_HUMAN	Serum paraoxonase/arylesterase 1	1673382	Purification of human serum paraoxonase/arylesterase. Evidence for one esterase catalyzing both activities.

P78314	3BP2_HUMAN	SH3 domain-binding protein 2	9299232	Identification and characterization of the human homologue of SH3BP2, an SH3 binding domain protein within a common region of deletion at 4p16.3 involved in bladder cancer.

Q02878	RL6_HUMAN	60S ribosomal protein L6	8457378	Isolation of a cDNA clone encoding DNA-binding protein (TAXREB107) that binds specifically to domain C of the tax-responsive enhancer element in the long terminal repeat of human T-cell leukemia virus type I.

P38719	DBP8_YEAST	ATP-dependent RNA helicase DBP8	11222764	Characterization and mutational analysis of yeast Dbp8p, a putative RNA helicase involved in ribosome biogenesis.

Q60520	SIN3A_MOUSE	Paired amphipathic helix protein Sin3a	11909966	Identification of mammalian Sds3 as an integral component of the Sin3/histone deacetylase corepressor complex.

P38873	KOG1_YEAST	Target of rapamycin complex 1 subunit KOG1	14562095	Global analysis of protein localization in budding yeast.

O95816	BAG2_HUMAN	BAG family molecular chaperone regulator 2	9873016	An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators.

P50170	RDH2_RAT	Retinol dehydrogenase 2	7499345	Cloning of a cDNA for a second retinol dehydrogenase type II. Expression of its mRNA relative to type I.

Q99PZ6	OSPG_SHIFL	Protein kinase OspG	11115111	The virulence plasmid pWR100 and the repertoire of proteins secreted by the type III secretion apparatus of Shigella flexneri.

Q06263	VTA1_YEAST	Vacuolar protein sorting-associated protein VTA1	12953057	Vps20p and Vta1p interact with Vps4p and function in multivesicular body sorting and endosomal transport in Saccharomyces cerevisiae.

Q62192	CD180_MOUSE	CD180 antigen	9686597	Mouse MD-1, a molecule that is physically associated with RP105 and positively regulates its expression.

Q9ZS34	CHLP_TOBAC	Geranylgeranyl diphosphate reductase, chloroplastic	10398704	Reduced activity of geranylgeranyl reductase leads to loss of chlorophyll and tocopherol and to partially geranylgeranylated chlorophyll in transgenic tobacco plants expressing antisense RNA for geranylgeranyl reductase.

Q21065	IFA3_CAEEL	Intermediate filament protein ifa-3	11427699	Essential roles for four cytoplasmic intermediate filament proteins in Caenorhabditis elegans development.

P56959	FUS_MOUSE	RNA-binding protein FUS	12950080	Mouse pigpen encodes a nuclear protein whose expression is developmentally regulated during craniofacial morphogenesis.

O48917	SQD1_ARATH	UDP-sulfoquinovose synthase, chloroplastic	11073956	Recombinant Arabidopsis SQD1 converts UDP-glucose and sulfite to the sulfolipid head group precursor UDP-sulfoquinovose in vitro.

Q9NYV4	CDK12_HUMAN	Cell division protein kinase 12	11683387	CrkRS: a novel conserved Cdc2-related protein kinase that colocalises with SC35 speckles.

Q13087	PDIA2_HUMAN	Protein disulfide-isomerase A2	8561901	Characterization and chromosomal localization of a new protein disulfide isomerase, PDIp, highly expressed in human pancreas.

Q22006	PRO1_CAEEL	Pre-rRNA-processing protein pro-1	14973273	C. elegans pro-1 activity is required for soma/germline interactions that influence proliferation and differentiation in the germ line.

Q8C145	S39A6_MOUSE	Zinc transporter ZIP6	11891044	Ermelin, an endoplasmic reticulum transmembrane protein, contains the novel HELP domain conserved in eukaryotes.

P10860	DHE3_RAT	Glutamate dehydrogenase 1, mitochondrial	9275181	Late memory-related genes in the hippocampus revealed by RNA fingerprinting.

Q09849	ARP42_SCHPO	SWI/SNF and RSC complexes subunit arp42	18622392	Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast.

Q04195	SIZ1_YEAST	E3 SUMO-protein ligase SIZ1	11577116	Yeast Ull1/Siz1 is a novel SUMO1/Smt3 ligase for septin components and functions as an adaptor between conjugating enzyme and substrates.

B0ZTE1	SOX21_XENLA	Transcription factor Sox-21	18956331	Cloning and developmental expression of the soxB2 genes, sox14 and sox21, during Xenopus laevis embryogenesis.

P35207	SKI2_YEAST	Antiviral helicase SKI2	10611222	Yeast exosome mutants accumulate 3'-extended polyadenylated forms of U4 small nuclear RNA and small nucleolar RNAs.

P87121	TAF2_SCHPO	Transcription initiation factor TFIID subunit 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9ES90	GPR35_MOUSE	G-protein coupled receptor 35	16754668	Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35.

O13559	YRF14_YEAST	Y' element ATP-dependent helicase protein 1 copy 4	9837911	Y'-Help1, a DNA helicase encoded by the yeast subtelomeric Y' element, is induced in survivors defective for telomerase.

Q8WZK1	RT21_SCHPO	40S ribosomal protein mrp21, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O00217	NDUS8_HUMAN	NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial	9666055	Genomic structure of the human NDUFS8 gene coding for the iron-sulfur TYKY subunit of the mitochondrial NADH:ubiquinone oxidoreductase.

O94534	ALP14_SCHPO	Spindle pole body component alp14	11432827	Fission yeast ch-TOG/XMAP215 homologue Alp14 connects mitotic spindles with the kinetochore and is a component of the Mad2-dependent spindle checkpoint.

P09007	SRD1_YEAST	Pre-rRNA-processing protein SRD1	14562095	Global analysis of protein localization in budding yeast.

P55862	MCM5A_XENLA	DNA replication licensing factor mcm5-A	9214647	Licensing of DNA replication by a multi-protein complex of MCM/P1 proteins in Xenopus eggs.

Q03660	TR130_YEAST	Transport protein particle 130 kDa subunit	10727015	Identification and characterization of five new subunits of TRAPP.

P57082	TBX4_HUMAN	T-box transcription factor TBX4	10945475	Virtual cloning and physical mapping of a human T-box gene, TBX4.

P91657	OPS5_DROME	Opsin Rh5	8982159	Identification of a novel Drosophila opsin reveals specific patterning of the R7 and R8 photoreceptor cells.

P32571	UBP4_YEAST	Ubiquitin carboxyl-terminal hydrolase 4	10069815	Interaction of the Doa4 deubiquitinating enzyme with the yeast 26S proteasome.

P48730	KC1D_HUMAN	Casein kinase I isoform delta	16618118	Dysbindin structural homologue CK1BP is an isoform-selective binding partner of human casein kinase-1.

P42684	ABL2_HUMAN	Tyrosine-protein kinase ABL2	15886098	RIN1 is an ABL tyrosine kinase activator and a regulator of epithelial-cell adhesion and migration.

Q9LN63	BZR2_ARATH	Protein BRASSINAZOLE-RESISTANT 2	12427989	Two putative BIN2 substrates are nuclear components of brassinosteroid signaling.

Q15361	TTF1_HUMAN	Transcription termination factor 1	7597036	Molecular evolution of mammalian ribosomal gene terminator sequences and the transcription termination factor TTF-1.

P38353	SSH1_YEAST	Sec sixty-one protein homolog	8612571	A second trimeric complex containing homologs of the Sec61p complex functions in protein transport across the ER membrane of S. cerevisiae.

P26232	CTNA2_HUMAN	Catenin alpha-2	8432524	Characterization and chromosomal assignment of a human cDNA encoding a protein related to the murine 102-kDa cadherin-associated protein (alpha-catenin).

O74348	YO88_SCHPO	Uncharacterized protein C21D10.08c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q07528	ATG20_YEAST	Autophagy-related protein 20	12048214	Cooperative binding of the cytoplasm to vacuole targeting pathway proteins, Cvt13 and Cvt20, to phosphatidylinositol 3-phosphate at the pre-autophagosomal structure is required for selective autophagy.

P39722	GEM1_YEAST	Mitochondrial Rho GTPase 1	16407407	Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins.

P39517	DHH1_YEAST	ATP-dependent RNA helicase DHH1	15166134	An essential role for the Saccharomyces cerevisiae DEAD-box helicase DHH1 in G1/S DNA-damage checkpoint recovery.

P27812	KRBBA_MOUSE	Killer cell lectin-like receptor subfamily B member 1B allele A	10229823	The NKR-P1B gene product is an inhibitory receptor on SJL/J NK cells.

P18427	FSHB_RAT	Follitropin subunit beta	2504572	Isolation and characterization of the gene encoding the beta-subunit of rat follicle-stimulating hormone.

Q9Y7Y1	SGM1_SCHPO	Protein sgm1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P83503	NYX_MOUSE	Nyctalopin	12506099	Identification of the gene and the mutation responsible for the mouse nob phenotype.

P17800	VIRBA_AGRT5	Protein virB10	2233252	Characterization of the virB operon of an Agrobacterium tumefaciens Ti plasmid: nucleotide sequence and protein analysis.

O95835	LATS1_HUMAN	Serine/threonine-protein kinase LATS1	18158288	Tumor suppressor LATS1 is a negative regulator of oncogene YAP.

Q6SJQ7	CLM1_MOUSE	CMRF35-like molecule 1	14662855	CMRF-35-like molecule-1, a novel mouse myeloid receptor, can inhibit osteoclast formation.

Q1JQ73	ELV1A_XENLA	ELAV-like protein 1-A	16199879	The Xenopus ELAV protein ElrB represses Vg1 mRNA translation during oogenesis.

Q01896	ATN2_YEAST	Sodium transport ATPase 2	7664728	The PMR2 gene cluster encodes functionally distinct isoforms of a putative Na+ pump in the yeast plasma membrane.

P51970	NDUA8_HUMAN	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8	9860297	The nuclear-encoded human NADH:ubiquinone oxidoreductase NDUFA8 subunit: cDNA cloning, chromosomal localization, tissue distribution, and mutation detection in complex-I-deficient patients.

Q1MTN7	RPM1_SCHPO	Exoribonuclease II, mitochondrial	18304578	The 3' ends of mature transcripts are generated by a processosome complex in fission yeast mitochondria.

P38910	CH10_YEAST	10 kDa heat shock protein, mitochondrial	7902576	Identification and functional analysis of chaperonin 10, the groES homolog from yeast mitochondria.

Q9SX77	UMP6_ARATH	Uncharacterized protein At1g47420, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P38406	GNAL_RAT	Guanine nucleotide-binding protein G(olf) subunit alpha	7494450	Molecular analysis of the multiple Golf alpha subunit mRNAs in the rat brain.

Q91926	VENT1_XENLA	Homeobox protein vent1	12050139	A study of mesoderm patterning through the analysis of the regulation of Xmyf-5 expression.

Q6A078	CE290_MOUSE	Centrosomal protein of 290 kDa	16632484	In-frame deletion in a novel centrosomal/ciliary protein CEP290/NPHP6 perturbs its interaction with RPGR and results in early-onset retinal degeneration in the rd16 mouse.

O95342	ABCBB_HUMAN	Bile salt export pump	9806540	A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis.

P31725	S10A9_MOUSE	Protein S100-A9	12529407	Loss of S100A9 (MRP14) results in reduced interleukin-8-induced CD11b surface expression, a polarized microfilament system, and diminished responsiveness to chemoattractants in vitro.

O42709	MCM10_SCHPO	DNA replication licensing factor mcm10	16720577	Fission yeast Mcm10p contains primase activity.

Q9ULD4	BRPF3_HUMAN	Bromodomain and PHD finger-containing protein 3	18794358	Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexes.

P97607	JAG2_RAT	Protein jagged-2	8948600	Jagged2: a serrate-like gene expressed during rat embryogenesis.

P54824	DDX6_XENLA	ATP-dependent RNA helicase ddx6	17074753	RAP55, a cytoplasmic mRNP component, represses translation in Xenopus oocytes.

Q1MTR5	YG66_SCHPO	Uncharacterized RING finger membrane protein C15C4.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q08960	TYW1_YEAST	tRNA wybutosine-synthesizing protein 1	16642040	Biosynthesis of wybutosine, a hyper-modified nucleoside in eukaryotic phenylalanine tRNA.

Q8N474	SFRP1_HUMAN	Secreted frizzled-related protein 1	9391078	SARPs: a family of secreted apoptosis-related proteins.

Q92990	GLMN_HUMAN	Glomulin	11845407	Mutations in a novel factor, glomulin, are responsible for glomuvenous malformations ('glomangiomas').

Q96RL7	VP13A_HUMAN	Vacuolar protein sorting-associated protein 13A	11381254	The gene encoding a newly discovered protein, chorein, is mutated in chorea-acanthocytosis.

P62745	RHOB_HUMAN	Rho-related GTP-binding protein RhoB	10508588	Regulation of epidermal growth factor receptor traffic by the small GTPase rhoB.

Q9V3Z6	MYO7A_DROME	Myosin-VIIa	16585515	Dimerized Drosophila myosin VIIa: a processive motor.

P61602	NCALD_BOVIN	Neurocalcin-delta	8387172	Neurocalcin family: a novel calcium-binding protein abundant in bovine central nervous system.

Q9UBD5	ORC3_HUMAN	Origin recognition complex subunit 3	10402192	Latheo encodes a subunit of the origin recognition complex and disrupts neuronal proliferation and adult olfactory memory when mutant.

O60243	H6ST1_HUMAN	Heparan-sulfate 6-O-sulfotransferase 1	9535912	Molecular characterization and expression of heparan-sulfate 6- sulfotransferase.

P53188	CGR1_YEAST	rRNA-processing protein CGR1	11932453	Identification of a role for Saccharomyces cerevisiae Cgr1p in pre- rRNA processing and 60S ribosome subunit synthesis.

Q13485	SMAD4_HUMAN	Mothers against decapentaplegic homolog 4	18568018	TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal.

Q9Y490	TLN1_HUMAN	Talin-1	15070891	Structural basis for amplifying vinculin activation by talin.

Q9JIA1	LGI1_MOUSE	Leucine-rich glioma-inactivated protein 1	15857855	ADPEAF mutations reduce levels of secreted LGI1, a putative tumor suppressor protein linked to epilepsy.

Q9W092	CHIT2_DROME	Probable chitinase 2	9662472	Chitinases are a multi-gene family in Aedes, Anopheles and Drosophila.

Q04235	TYW2_YEAST	tRNA wybutosine-synthesizing protein 2	14562095	Global analysis of protein localization in budding yeast.

O75807	PR15A_HUMAN	Protein phosphatase 1 regulatory subunit 15A	9153226	Mammalian GADD34, an apoptosis- and DNA damage-inducible gene.

Q6TY21	EPA2B_XENLA	Embryonic polyadenylate-binding protein 2-B	15083517	Xenopus embryonic poly(A) binding protein 2 (ePABP2) defines a new family of cytoplasmic poly(A) binding proteins expressed during the early stages of vertebrate development.

Q38860	KCS18_ARATH	3-ketoacyl-CoA synthase 18	11341960	Active-site residues of a plant membrane-bound fatty acid elongase beta-ketoacyl-CoA synthase, FAE1 KCS.

Q02156	KPCE_HUMAN	Protein kinase C epsilon type	15632189	Translocation of diacylglycerol kinase theta from cytosol to plasma membrane in response to activation of G protein-coupled receptors and protein kinase C.

Q6YFQ2	CX6B2_HUMAN	Cytochrome c oxidase subunit 6B2	12874793	Cytochrome c oxidase of mammals contains a testes-specific isoform of subunit VIb -- the counterpart to testes-specific cytochrome c?

Q91XM9	DLG2_MOUSE	Disks large homolog 2	19243221	Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning.

Q63850	NUP62_MOUSE	Nuclear pore glycoprotein p62	1915419	Nuclear pore complex glycoprotein p62 of Xenopus laevis and mouse: cDNA cloning and identification of its glycosylated region.

P43587	YPI1_YEAST	Type 1 phosphatases regulator YPI1	17142459	YPI1 and SDS22 proteins regulate the nuclear localization and function of yeast type 1 phosphatase Glc7.

Q54PR9	CF60_DICDI	Counting factor 60	16963635	A 60-kilodalton protein component of the counting factor complex regulates group size in Dictyostelium discoideum.

P70041	CER1_XENLA	Cerberus	17123501	Multiple functions of Cerberus cooperate to induce heart downstream of Nodal.

Q03532	HAS1_YEAST	ATP-dependent RNA helicase HAS1	15718299	Characterization of the ATPase and unwinding activities of the yeast DEAD-box protein Has1p and the analysis of the roles of the conserved motifs.

Q6E1M8	AWAT2_MOUSE	Acyl-CoA wax alcohol acyltransferase 2	15220349	Mammalian wax biosynthesis. II. Expression cloning of wax synthase cDNAs encoding a member of the acyltransferase enzyme family.

Q84UT5	BLE3_ORYSJ	UPF0497 membrane protein BLE3	16808934	OsBLE3, a brassinolide-enhanced gene, is involved in the growth of rice.

O88788	AG10B_RAT	Putative alpha-1,2-glucosyltransferase ALG10-B	9722534	KCR1, a membrane protein that facilitates functional expression of non-inactivating K+ currents associates with rat EAG voltage-dependent K+ channels.

O49608	MYB32_ARATH	Transcription factor MYB32	16463103	The MYB transcription factor superfamily of Arabidopsis: expression analysis and phylogenetic comparison with the rice MYB family.

Q8H112	PGL1A_ARATH	PGR5-like protein 1A, chloroplastic	18243102	A complex containing PGRL1 and PGR5 is involved in the switch between linear and cyclic electron flow in Arabidopsis.

O95198	KLHL2_HUMAN	Kelch-like protein 2	10397770	Characterization of Mayven, a novel actin-binding protein predominantly expressed in brain.

Q9HDU4	YHEB_SCHPO	Uncharacterized protein PB2B2.11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NPA8	ENY2_HUMAN	Enhancer of yellow 2 transcription factor homolog	18206972	A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing.

Q14314	FGL2_HUMAN	Fibroleukin	7642106	Sequence of a human transcript expressed in T-lymphocytes and encoding a fibrinogen-like protein.

Q9TY03	FRDA_CAEEL	Frataxin, mitochondrial	16293572	Reduction of Caenorhabditis elegans frataxin increases sensitivity to oxidative stress, reduces lifespan, and causes lethality in a mitochondrial complex II mutant.

P19018	TRA2_DROME	Transformer-2 sex-determining protein	2493992	The sex determination locus transformer-2 of Drosophila encodes a polypeptide with similarity to RNA binding proteins.

P61224	RAP1B_HUMAN	Ras-related protein Rap-1b	18660803	Structure of Epac2 in complex with a cyclic AMP analogue and RAP1B.

Q9UHA7	IL1F6_HUMAN	Interleukin-1 family member 6	10625660	Four new members expand the IL-1 superfamily.

Q9C0X8	RRP12_SCHPO	Putative ribosomal RNA-processing protein 12	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q62880	TAF9B_RAT	Transcription initiation factor TFIID subunit 9B	9168994	Rat TAFII31 gene is induced upon programmed cell death in differentiated PC12 cells deprived of NGF.

O74493	YCR5_SCHPO	Uncharacterized protein C285.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O13752	YF22_SCHPO	Uncharacterized TLC domain-containing protein C17A2.02c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P07451	CAH3_HUMAN	Carbonic anhydrase 3	3086182	Nucleotide sequence and derived amino acid sequence of a cDNA encoding human muscle carbonic anhydrase.

P36776	LONM_HUMAN	Lon protease homolog, mitochondrial	8248235	A human mitochondrial ATP-dependent protease that is highly homologous to bacterial Lon protease.

O94537	PPK4_SCHPO	Serine/threonine-protein kinase ppk4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q03433	VPS71_YEAST	Vacuolar protein sorting-associated protein 71	14562095	Global analysis of protein localization in budding yeast.

O43374	RASL2_HUMAN	Ras GTPase-activating protein 4	11448776	CAPRI regulates Ca(2+)-dependent inactivation of the Ras-MAPK pathway.

O70161	PI51C_MOUSE	Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma	9535851	Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase family.

O00750	P3C2B_HUMAN	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit beta	9830063	Human phosphoinositide 3-kinase C2beta, the role of calcium and the C2 domain in enzyme activity.

Q5Y5T2	ZDH18_MOUSE	Palmitoyltransferase ZDHHC18	15603741	Identification of PSD-95 palmitoylating enzymes.

Q14728	MFS10_HUMAN	Major facilitator superfamily domain-containing protein 10	8353488	A gene from chromosome 4p16.3 with similarity to a superfamily of transporter proteins.

P92939	ECA1_ARATH	Calcium-transporting ATPase 1, endoplasmic reticulum-type	12226493	An endoplasmic reticulum-bound Ca(2+)/Mn(2+) pump, ECA1, supports plant growth and confers tolerance to Mn(2+) stress.

Q9UU87	PPK34_SCHPO	Serine/threonine-protein kinase ppk34	15821139	Systematic deletion analysis of fission yeast protein kinases.

P08686	CP21A_HUMAN	Steroid 21-hydroxylase	1406709	R339H and P453S: CYP21 mutations associated with nonclassic steroid 21-hydroxylase deficiency that are not apparent gene conversions.

O59945	FIMB_SCHPO	Fimbrin	11294907	Roles of a fimbrin and an alpha-actinin-like protein in fission yeast cell polarization and cytokinesis.

Q9Y2Q9	RT28_HUMAN	28S ribosomal protein S28, mitochondrial	10938081	A proteomics approach to the identification of mammalian mitochondrial small subunit ribosomal proteins.

Q9NRD9	DUOX1_HUMAN	Dual oxidase 1	16111680	Differential regulation of dual NADPH oxidases/peroxidases, Duox1 and Duox2, by Th1 and Th2 cytokines in respiratory tract epithelium.

P46667	ATHB5_ARATH	Homeobox-leucine zipper protein ATHB-5	12678559	The Arabidopsis thaliana homeobox gene ATHB5 is a potential regulator of abscisic acid responsiveness in developing seedlings.

Q9P7A1	YN82_SCHPO	UPF0424 protein P35G2.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P87219	SOU1_CANAL	Sorbose reductase SOU1	16134116	Candida albicans SOU1 encodes a sorbose reductase required for L- sorbose utilization.

Q14766	LTBP1_HUMAN	Latent-transforming growth factor beta-binding protein 1	8537398	Efficient association of an amino-terminally extended form of human latent transforming growth factor-beta binding protein with the extracellular matrix.

Q8W4L5	VAL1_ARATH	B3 domain-containing transcription repressor VAL1	19962994	PAH-domain-specific interactions of the Arabidopsis transcription coregulator SIN3-LIKE1 (SNL1) with telomere-binding protein 1 and ALWAYS EARLY2 Myb-DNA binding factors.

Q9LX31	GUN4C_ARATH	Tetrapyrrole-binding protein, chloroplastic	12574634	GUN4, a regulator of chlorophyll synthesis and intracellular signaling.

Q99720	SGMR1_HUMAN	Sigma non-opioid intracellular receptor 1	8954936	Cloning and functional expression of the human type 1 sigma receptor (hSigmaR1).

P35349	GRM6_RAT	Metabotropic glutamate receptor 6	8389366	Molecular characterization of a novel retinal metabotropic glutamate receptor mGluR6 with a high agonist selectivity for L-2-amino-4- phosphonobutyrate.

Q39021	MPK1_ARATH	Mitogen-activated protein kinase 1	8130795	Characterization of two cDNAs that encode MAP kinase homologues in Arabidopsis thaliana and analysis of the possible role of auxin in activating such kinase activities in cultured cells.

P49597	P2C56_ARATH	Protein phosphatase 2C 56	19874541	PYR/PYL/RCAR family members are major in-vivo ABI1 protein phosphatase 2C-interacting proteins in Arabidopsis.

P62241	RS8_HUMAN	40S ribosomal protein S8	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

Q9LY50	ACCR3_ARATH	Putative serine/threonine-protein kinase-like protein CCR3	18539132	Dimerization properties of the transmembrane domains of Arabidopsis CRINKLY4 receptor-like kinase and homologs.

P40454	PTPA1_YEAST	Serine/threonine-protein phosphatase 2A activator 1	15150670	The yeast phosphotyrosyl phosphatase activator protein, yPtpa1/Rrd1, interacts with Sit4 phosphatase to mediate resistance to 4- nitroquinoline-1-oxide and UVA.

P13405	RB_MOUSE	Retinoblastoma-associated protein	15983387	Frag1, a homolog of alternative replication factor C subunits, links replication stress surveillance with apoptosis.

Q09433	THIO1_CAEEL	Thioredoxin-1	16387300	Lifespan decrease in a Caenorhabditis elegans mutant lacking TRX-1, a thioredoxin expressed in ASJ sensory neurons.

O43318	M3K7_HUMAN	Mitogen-activated protein kinase kinase kinase 7	17449468	RBCK1 negatively regulates tumor necrosis factor- and interleukin-1- triggered NF-kappaB activation by targeting TAB2/3 for degradation.

Q9NZV8	KCND2_HUMAN	Potassium voltage-gated channel subfamily D member 2	15358149	Protein-protein interactions of KChIP proteins and Kv4.2.

P14210	HGF_HUMAN	Hepatocyte growth factor	2531289	Molecular cloning and expression of human hepatocyte growth factor.

Q38828	IAA10_ARATH	Auxin-responsive protein IAA10	12036262	Genetics of Aux/IAA and ARF action in plant growth and development.

P92189	STIL_DROME	Protein stand still	9093851	stand still, a Drosophila gene involved in the female germline for proper survival, sex determination and differentiation.

Q9SVM8	GRP2_ARATH	Glycine-rich RNA-binding protein 2, mitochondrial	11743114	Proteomic approach to identify novel mitochondrial proteins in Arabidopsis.

Q99ML2	TNK1_MOUSE	Non-receptor tyrosine-protein kinase TNK1	12789265	Kos1, a nonreceptor tyrosine kinase that suppresses Ras signaling.

Q92963	RIT1_HUMAN	GTP-binding protein Rit1	8824319	Rin, a neuron-specific and calmodulin-binding small G-protein, and Rit define a novel subfamily of ras proteins.

P50077	CCH1_YEAST	Calcium-channel protein CCH1	10958666	A homolog of voltage-gated Ca(2+) channels stimulated by depletion of secretory Ca(2+) in yeast.

Q9ZPH9	PMTF_ARATH	Probable methyltransferase PMT15	16618929	Mapping the Arabidopsis organelle proteome.

Q9ZWS6	ARR6_ARATH	Two-component response regulator ARR6	11115887	Characterization of the response of the Arabidopsis response regulator gene family to cytokinin.

Q92462	PUB1_SCHPO	E3 ubiquitin-protein ligase pub1	9197411	Tolerance of low pH in Schizosaccharomyces pombe requires a functioning pub1 ubiquitin ligase.

O74747	RAD18_SCHPO	Postreplication repair E3 ubiquitin-protein ligase rad18	11523791	A homologue of the Rad18 postreplication repair gene is required for DNA damage responses throughout the fission yeast cell cycle.

P70196	TRAF6_MOUSE	TNF receptor-associated factor 6	18849341	FLN29 deficiency reveals its negative regulatory role in the Toll- like receptor (TLR) and retinoic acid-inducible gene I (RIG-I)-like helicase signaling pathway.

Q7KN62	TERA_DROME	Transitional endoplasmic reticulum ATPase TER94	10564274	Identification of TER94, an AAA ATPase protein, as a Bam-dependent component of the Drosophila fusome.

Q9LQ73	PX11C_ARATH	Peroxisomal membrane protein 11C	17220199	The PEROXIN11 protein family controls peroxisome proliferation in Arabidopsis.

Q99523	SORT_HUMAN	Sortilin	10085125	Sortilin/neurotensin receptor-3 binds and mediates degradation of lipoprotein lipase.

P33205	FXA4A_XENLA	Forkhead box protein A4-A	1483397	Pintallavis, a gene expressed in the organizer and midline cells of frog embryos: involvement in the development of the neural axis.

Q8MIR4	COASY_PIG	Bifunctional coenzyme A synthase	11994049	Identification and characterization of the gene encoding the human phosphopantetheine adenylyltransferase and dephospho-CoA kinase bifunctional enzyme (CoA synthase).

Q505F1	NR2C1_MOUSE	Nuclear receptor subfamily 2 group C member 1	9071982	Distinct expression patterns and biological activities of two isoforms of the mouse orphan receptor TR2.

Q91Y55	CLD16_RAT	Claudin-16	11729235	Primary gene structure and expression studies of rodent paracellin- 1.

P46199	IF2M_HUMAN	Translation initiation factor IF-2, mitochondrial	7829522	Cloning and sequence analysis of the human mitochondrial translational initiation factor 2 cDNA.

Q12373	HIF1_YEAST	HAT1-interacting factor 1	14562095	Global analysis of protein localization in budding yeast.

Q9NR82	KCNQ5_HUMAN	Potassium voltage-gated channel subfamily KQT member 5	10787416	Molecular cloning and functional expression of KCNQ5, a potassium channel subunit that may contribute to neuronal M-current diversity.

Q9LUS2	TC120_ARATH	Translocase of chloroplast 120, chloroplastic	10646606	The major protein import receptor of plastids is essential for chloroplast biogenesis.

O75899	GABR2_HUMAN	Gamma-aminobutyric acid type B receptor subunit 2	9872316	Heterodimerization is required for the formation of a functional GABA(B) receptor.

Q9XF04	CLV3_ARATH	Protein CLAVATA 3	16902141	A plant peptide encoded by CLV3 identified by in situ MALDI-TOF MS analysis.

P04637	P53_HUMAN	Cellular tumor antigen p53	12750254	p29ING4 and p28ING5 bind to p53 and p300, and enhance p53 activity.

Q9Z0W3	NU160_MOUSE	Nuclear pore complex protein Nup160	11684705	Novel vertebrate nucleoporins Nup133 and Nup160 play a role in mRNA export.

Q9JI71	DLL4_MOUSE	Delta-like protein 4	10837024	Dll4, a novel Notch ligand expressed in arterial endothelium.

Q18120	TWK18_CAEEL	TWiK family of potassium channels protein 18	11027209	Mutants of a temperature-sensitive two-P domain potassium channel.

Q8IN94	OSA_DROME	Trithorax group protein osa	9895321	The trithorax group gene osa encodes an ARID-domain protein that genetically interacts with the brahma chromatin-remodeling factor to regulate transcription.

O94521	PLR2_SCHPO	Probable pyridoxal reductase 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9USR1	TXL1_SCHPO	Thioredoxin-like protein 1	17476701	The txl1+ gene from Schizosaccharomyces pombe encodes a new thioredoxin-like 1 protein that participates in the antioxidant defence against tert-butyl hydroperoxide.

Q15853	USF2_HUMAN	Upstream stimulatory factor 2	8954795	Structure, sequence, and chromosome 19 localization of human USF2 and its rearrangement in a patient with multicystic renal dysplasia.

P55000	SLUR1_HUMAN	Secreted Ly-6/uPAR-related protein 1	11285253	Mutations in the gene encoding SLURP-1 in Mal de Meleda.

Q39255	SKP1A_ARATH	SKP1-like protein 1A	12169662	The F-box subunit of the SCF E3 complex is encoded by a diverse superfamily of genes in Arabidopsis.

Q5S2C4	NCKP1_ARATH	Protein NAP1	15294869	Interchangeable functions of Arabidopsis PIROGI and the human WAVE complex subunit SRA1 during leaf epidermal development.

P26392	RMLD_SALTY	dTDP-4-dehydrorhamnose reductase	12057193	Variation on a theme of SDR. dTDP-6-deoxy-L- lyxo-4-hexulose reductase (RmlD) shows a new Mg2+-dependent dimerization mode.

Q92772	CDKL2_HUMAN	Cyclin-dependent kinase-like 2	9000130	Molecular cloning of the epidermal growth factor-stimulated protein kinase p56 KKIAMRE.

Q92535	PIGC_HUMAN	Phosphatidylinositol N-acetylglucosaminyltransferase subunit C	8806613	PIG-C, one of the three human genes involved in the first step of glycosylphosphatidylinositol biosynthesis is a homologue of Saccharomyces cerevisiae GPI2.

P36021	MOT8_HUMAN	Monocarboxylate transporter 8	7981683	A novel transmembrane transporter encoded by the XPCT gene in Xq13.2.

P04637	P53_HUMAN	Cellular tumor antigen p53	11706030	Differential effect of ik3-1/cables on p53- and p73-induced cell death.

P53145	LSG1_YEAST	Large subunit GTPase 1	12773575	The putative GTPases Nog1p and Lsg1p are required for 60S ribosomal subunit biogenesis and are localized to the nucleus and cytoplasm, respectively.

Q9VH19	LMLN_DROME	Leishmanolysin-like peptidase	15557119	Invadolysin: a novel, conserved metalloprotease links mitotic structural rearrangements with cell migration.

P49893	WN11B_XENLA	Protein Wnt-11b	12167861	Wnt-11 activation of a non-canonical Wnt signalling pathway is required for cardiogenesis.

P42763	ERD14_ARATH	Dehydrin ERD14	8069491	Characterization of two cDNAs (ERD10 and ERD14) corresponding to genes that respond rapidly to dehydration stress in Arabidopsis thaliana.

O42667	SSM4_SCHPO	Microtubule-associated protein ssm4	9167972	Microtubule-associated coiled-coil protein Ssm4 is involved in the meiotic development in fission yeast.

O95405	ZFYV9_HUMAN	Zinc finger FYVE domain-containing protein 9	9582421	Identification of a novel serine protease-like molecule in human brain.

Q9UNU6	CP8B1_HUMAN	7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase	10051404	Structure and chromosomal assignment of the sterol 12alpha- hydroxylase gene (CYP8B1) in human and mouse: eukaryotic cytochrome P- 450 gene devoid of introns.

P53939	NIS1_YEAST	Protein NIS1	11817649	Nis1 encoded by YNL078W: a new neck protein of Saccharomyces cerevisiae.

Q9M390	PTR1_ARATH	Peptide transporter PTR1	18753286	AtPTR1 and AtPTR5 transport dipeptides in planta.

Q9Y251	HPSE_HUMAN	Heparanase	10446189	Human heparanase. Purification, characterization, cloning, and expression.

Q9H2G9	GO45_HUMAN	Golgin-45	11739401	A GRASP55-rab2 effector complex linking Golgi structure to membrane traffic.

Q9SLE4	UBC29_ARATH	Ubiquitin-conjugating enzyme E2 29	16339806	Genome analysis and functional characterization of the E2 and RING- type E3 ligase ubiquitination enzymes of Arabidopsis.

P39706	SWD1_YEAST	COMPASS component SWD1	11742990	The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4.

O74359	MUG60_SCHPO	Meiotically up-regulated gene 60 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9U9R7	SNAG_DICDI	Gamma-soluble NSF attachment protein	10727946	Functional and molecular identification of novel members of the ubiquitous membrane fusion proteins alpha- and gamma-SNAP (soluble N- ethylmaleimide-sensitive factor-attachment proteins) families in Dictyostelium discoideum.

Q9UK23	NAGPA_HUMAN	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase	10551838	Molecular cloning and functional expression of two splice forms of human N-acetylglucosamine-1-phosphodiester alpha-N- acetylglucosaminidase.

P39946	NUDF_YEAST	Nuclear distribution protein PAC1	15965467	NudEL targets dynein to microtubule ends through LIS1.

P39112	DSS1_YEAST	Exoribonuclease II, mitochondrial	12426313	The yeast mitochondrial degradosome. Its composition, interplay between RNA helicase and RNase activities and the role in mitochondrial RNA metabolism.

P54263	SYN_THET8	Asparaginyl-tRNA synthetase	8706760	Asparaginyl-tRNA synthetase from Thermus thermophilus HB8. Sequence of the gene and crystallization of the enzyme expressed in Escherichia coli.

Q7T103	P5F11_XENLA	POU domain, class 5, transcription factor 1.1	16860542	Xenopus POU factors of subclass V inhibit activin/nodal signaling during gastrulation.

P87227	MIS6_SCHPO	Inner centromere protein mis6	15369671	Mis16 and Mis18 are required for CENP-A loading and histone deacetylation at centromeres.

P39001	UME6_YEAST	Transcriptional regulatory protein UME6	9150136	Repression by Ume6 involves recruitment of a complex containing Sin3 corepressor and Rpd3 histone deacetylase to target promoters.

P46933	APBB1_RAT	Amyloid beta A4 precursor protein-binding family B member 1	18922798	Dexras1 interacts with FE65 to regulate FE65-amyloid precursor protein-dependent transcription.

Q9UGM3	DMBT1_HUMAN	Deleted in malignant brain tumors 1 protein	10485905	Cloning of gp-340, a putative opsonin receptor for lung surfactant protein D.

P54750	PDE1A_HUMAN	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	8557689	Isolation and characterization of cDNAs corresponding to two human calcium, calmodulin-regulated, 3',5'-cyclic nucleotide phosphodiesterases.

O23661	ARFC_ARATH	Auxin response factor 3	10476078	Dimerization and DNA binding of auxin response factors.

P32343	SSH4_YEAST	Protein SSH4	17287526	Ssh4, Rcr2 and Rcr1 affect plasma membrane transporter activity in Saccharomyces cerevisiae.

O59743	YN27_SCHPO	Uncharacterized protein C530.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P42519	STAR_DROME	Protein Star	11672524	Regulated intracellular ligand transport and proteolysis control EGF signal activation in Drosophila.

P52948	NUP98_HUMAN	Nuclear pore complex protein Nup98-Nup96	10087256	A conserved biogenesis pathway for nucleoporins: proteolytic processing of a 186-kilodalton precursor generates Nup98 and the novel nucleoporin, Nup96.

Q02248	CTNB1_MOUSE	Catenin beta-1	10882138	Structure of the dimerization and beta-catenin-binding region of alpha-catenin.

Q9D304	RN128_MOUSE	E3 ubiquitin-protein ligase RNF128	12435366	The E3 ubiquitin ligase GREUL1 anteriorizes ectoderm during Xenopus development.

P0CF52	KDM7B_DANRE	Lysine-specific demethylase 7B	20194436	KDM7 is a dual demethylase for histone H3 Lys 9 and Lys 27 and functions in brain development.

P16912	KDC2_DROME	Protein kinase DC2	8601490	Activity, expression and function of a second Drosophila protein kinase A catalytic subunit gene.

Q16775	GLO2_HUMAN	Hydroxyacylglutathione hydrolase, mitochondrial	8550579	Molecular cloning, heterologous expression, and characterization of human glyoxalase II.

Q8C208	IKZF4_MOUSE	Zinc finger protein Eos	10218586	Eos: a novel member of the Ikaros gene family expressed predominantly in the developing nervous system.

Q5XJA0	TYDP2_DANRE	Tyrosyl-DNA phosphodiesterase 2	18039968	Ttrap is an essential modulator of Smad3-dependent Nodal signaling during zebrafish gastrulation and left-right axis determination.

O14264	YFP9_SCHPO	Uncharacterized protein C7D4.09c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UBD6	RHCG_HUMAN	Ammonium transporter Rh type C	14761968	NH3 is involved in the NH4+ transport induced by the functional expression of the human Rh C glycoprotein.

Q99N91	RM34_MOUSE	39S ribosomal protein L34, mitochondrial	11279069	Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria.

Q8W4J8	TIF7_ARATH	Protein TIFY 7	20360743	NINJA connects the co-repressor TOPLESS to jasmonate signalling.

P21900	PURA_DICDI	Adenylosuccinate synthetase	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q62799	ERBB3_RAT	Receptor tyrosine-protein kinase erbB-3	9030624	Expression of neuregulins and their putative receptors, ErbB2 and ErbB3, is induced during Wallerian degeneration.

Q9ZPY8	AIB_ARATH	Transcription factor ABA-INDUCIBLE bHLH-TYPE	17828375	The bHLH-type transcription factor AtAIB positively regulates ABA response in Arabidopsis.

P27701	CD82_HUMAN	CD82 antigen	7754374	KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2.

O88869	RASF9_RAT	Ras association domain-containing protein 9	9837933	P-CIP1, a novel protein that interacts with the cytosolic domain of peptidylglycine alpha-amidating monooxygenase, is associated with endosomes.

Q9HCN4	GPN1_HUMAN	GPN-loop GTPase 1	11058119	A novel cytoplasmic GTPase XAB1 interacts with DNA repair protein XPA.

Q06451	TPO3_YEAST	Polyamine transporter 3	12562762	Localization and function of the yeast multidrug transporter Tpo1p.

P14151	LYAM1_HUMAN	L-selectin	1692315	Structure of the gene encoding the human leukocyte adhesion molecule- 1 (TQ1, Leu-8) of lymphocytes and neutrophils.

Q9ZVL6	U603_ARATH	UPF0603 protein At1g54780, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q99ML9	RN111_MOUSE	E3 ubiquitin-protein ligase Arkadia	11298452	Induction of the mammalian node requires Arkadia function in the extraembryonic lineages.

P47146	ABM1_YEAST	Aberrant microtubules protein 1	10628851	Functional analysis of 150 deletion mutants in Saccharomyces cerevisiae by a systematic approach.

P21595	CP56_YEAST	Cytochrome P450-DIT2	8183942	The sporulation-specific enzymes encoded by the DIT1 and DIT2 genes catalyze a two-step reaction leading to a soluble LL-dityrosine- containing precursor of the yeast spore wall.

P54253	ATX1_HUMAN	Ataxin-1	11136710	The spinocerebellar ataxia type 1 protein, ataxin-1, has RNA-binding activity that is inversely affected by the length of its polyglutamine tract.

P15151	PVR_HUMAN	Poliovirus receptor	15039383	Functional characterization of DNAM-1 (CD226) interaction with its ligands PVR (CD155) and nectin-2 (PRR-2/CD112).

Q8JG69	AA2DB_DANRE	Alpha-2Db adrenergic receptor	15655522	Conserved structural, pharmacological and functional properties among the three human and five zebrafish alpha2-adrenoceptors.

P38181	NU170_YEAST	Nucleoporin NUP170	9864357	Specific binding of the karyopherin Kap121p to a subunit of the nuclear pore complex containing Nup53p, Nup59p, and Nup170p.

Q8VZI8	FTSHA_ARATH	ATP-dependent zinc metalloprotease FTSH 10, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q12060	HFI1_YEAST	Transcriptional coactivator HFI1/ADA1	9154821	ADA1, a novel component of the ADA/GCN5 complex, has broader effects than GCN5, ADA2, or ADA3.

Q39024	MPK4_ARATH	Mitogen-activated protein kinase 4	15225555	The MKK2 pathway mediates cold and salt stress signaling in Arabidopsis.

Q12802	AKP13_HUMAN	A-kinase anchor protein 13	9891067	Activation of the Lbc Rho exchange factor proto-oncogene by truncation of an extended C terminus that regulates transformation and targeting.

P49334	TOM22_YEAST	Mitochondrial import receptor subunit TOM22	10519552	Tom22 is a multifunctional organizer of the mitochondrial preprotein translocase.

P43429	GATA1_RAT	Erythroid transcription factor	7957872	Expression of GATA-binding transcription factors in rat hepatocytes.

Q0V7X4	FIT_ARATH	Transcription factor FER-LIKE IRON DEFICIENCY-INDUCED TRANSCRIPTION FACTOR	15539473	The essential basic helix-loop-helix protein FIT1 is required for the iron deficiency response.

P48740	MASP1_HUMAN	Mannan-binding lectin serine protease 1	10946292	Proteolytic activities of two types of mannose-binding lectin- associated serine protease.

Q14155	ARHG7_HUMAN	Rho guanine nucleotide exchange factor 7	19118189	Preso, a novel PSD-95-interacting FERM and PDZ domain protein that regulates dendritic spine morphogenesis.

Q10073	YAN8_SCHPO	Uncharacterized CCDC90 family protein C3H1.08c, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P05451	REG1A_HUMAN	Lithostathine-1-alpha	2332435	Complete nucleotide sequence of human reg gene and its expression in normal and tumoral tissues. The reg protein, pancreatic stone protein, and pancreatic thread protein are one and the same product of the gene.

Q550L8	IFKB_DICDI	Probable serine/threonine-protein kinase ifkB	12697064	IfkA, a presumptive eIF2 alpha kinase of Dictyostelium, is required for proper timing of aggregation and regulation of mound size.

Q9USK1	YJ2B_SCHPO	Uncharacterized bolA-like protein C4B3.11c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9JKF8	RASD1_RAT	Dexamethasone-induced Ras-related protein 1	11086993	Dexras1: a G protein specifically coupled to neuronal nitric oxide synthase via CAPON.

P23301	IF5A1_YEAST	Eukaryotic translation initiation factor 5A-1	16215987	Tandem affinity purification revealed the hypusine-dependent binding of eukaryotic initiation factor 5A to the translating 80S ribosomal complex.

Q11002	CANA_DROME	Calpain-A	7823949	CalpA, a Drosophila calpain homolog specifically expressed in a small set of nerve, midgut, and blood cells.

Q12211	PUS1_YEAST	tRNA pseudouridine synthase 1	8641292	Nuclear pore proteins are involved in the biogenesis of functional tRNA.

P86098	NXL4_MICSU	Long neurotoxin MS4	18384102	Proteomic analysis of the venom from the fish eating coral snake Micrurus surinamensis: novel toxins, their function and phylogeny.

Q8NCG5	CHST4_HUMAN	Carbohydrate sulfotransferase 4	10330415	Sulfotransferases of two specificities function in the reconstitution of high endothelial cell ligands for L-selectin.

Q9UU96	GRC3_SCHPO	Protein grc3	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

O43818	U3IP2_HUMAN	U3 small nucleolar RNA-interacting protein 2	9418896	cDNA cloning and characterization of the human U3 small nucleolar ribonucleoprotein complex-associated 55-kilodalton protein.

P96205	DRRA_MYCTU	Doxorubicin resistance ATP-binding protein drrA	12057006	Overexpression and functional characterization of an ABC (ATP-binding cassette) transporter encoded by the genes drrA and drrB of Mycobacterium tuberculosis.

P36152	DRE2_YEAST	Fe-S cluster assembly protein DRE2	14562095	Global analysis of protein localization in budding yeast.

Q9NRD9	DUOX1_HUMAN	Dual oxidase 1	11514595	Tyrosine cross-linking of extracellular matrix is catalyzed by Duox, a multidomain oxidase/peroxidase with homology to the phagocyte oxidase subunit gp91phox.

Q9NQC1	JADE2_HUMAN	Protein Jade-2	16387653	ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.

Q9P6S5	ASK1_SCHPO	DASH complex subunit ask1	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

Q96B97	SH3K1_HUMAN	SH3 domain-containing kinase-binding protein 1	12218189	Cbl-directed monoubiquitination of CIN85 is involved in regulation of ligand-induced degradation of EGF receptors.

Q86YL7	PDPN_HUMAN	Podoplanin	10393083	Cloning and characterization of gp36, a human mucin-type glycoprotein preferentially expressed in vascular endothelium.

P35723	YET1_YEAST	Endoplasmic reticulum transmembrane protein 1	14562095	Global analysis of protein localization in budding yeast.

P55108	BMP3B_RAT	Bone morphogenetic protein 3B	8605043	Identification of rat bone morphogenetic protein-3b (BMP-3b), a new member of BMP-3.

P07902	GALT_HUMAN	Galactose-1-phosphate uridylyltransferase	1897530	Molecular characterization of two galactosemia mutations: correlation of mutations with highly conserved domains in galactose-1-phosphate uridyl transferase.

Q8N122	RPTOR_HUMAN	Regulatory-associated protein of mTOR	12408816	Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control.

Q61194	P3C2A_MOUSE	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit alpha	8663140	Mouse p170 is a novel phosphatidylinositol 3-kinase containing a C2 domain.

O95278	EPM2A_HUMAN	Laforin	11001928	Laforin, defective in the progressive myoclonus epilepsy of Lafora type, is a dual-specificity phosphatase associated with polyribosomes.

P38820	UBA4_YEAST	Adenylyltransferase and sulfurtransferase UBA4	10713047	A protein conjugation system in yeast with homology to biosynthetic enzyme reaction of prokaryotes.

O15209	ZBT22_HUMAN	Zinc finger and BTB domain-containing protein 22	9545376	TAPASIN, DAXX, RGL2, HKE2 and four new genes (BING 1, 3 to 5) form a dense cluster at the centromeric end of the MHC.

O70594	S22A5_RAT	Solute carrier family 22 member 5	9792817	Molecular cloning and characterization of high-affinity carnitine transporter from rat intestine.

P60983	GMFB_HUMAN	Glia maturation factor beta	1712830	Molecular cloning and expression of biologically active human glia maturation factor-beta.

Q92562	FIG4_HUMAN	Polyphosphoinositide phosphatase	17556371	Core protein machinery for mammalian phosphatidylinositol 3,5- bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complex.

P17844	DDX5_HUMAN	Probable ATP-dependent RNA helicase DDX5	2451786	Nuclear protein with sequence homology to translation initiation factor eIF-4A.

P62277	RS13_HUMAN	40S ribosomal protein S13	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

Q92765	SFRP3_HUMAN	Secreted frizzled-related protein 3	8824257	Primary structure and tissue distribution of FRZB, a novel protein related to Drosophila frizzled, suggest a role in skeletal morphogenesis.

Q93142	FAR1_BRUMA	Fatty-acid and retinol-binding protein 1	12106870	The FAR proteins of filarial nematodes: secretion, glycosylation and lipid binding characteristics.

Q9V3P0	PRDX1_DROME	Peroxiredoxin 1	10632718	Polypeptides differentially expressed in imaginal discs define the peroxiredoxin family of genes in Drosophila.

Q00839	HNRPU_HUMAN	Heterogeneous nuclear ribonucleoprotein U	19029303	Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs.

Q800K6	TOB1A_XENLA	DNA topoisomerase 2-binding protein 1-A	20116089	Treslin collaborates with TopBP1 in triggering the initiation of DNA replication.

O17645	HST2_CAEEL	Heparan sulfate 2-O-sulfotransferase hst-2	15003172	Differential sulfations and epimerization define heparan sulfate specificity in nervous system development.

P83268	IF2A_RABIT	Eukaryotic translation initiation factor 2 subunit 1	3592677	The purification and characterization of subunits alpha, beta, and gamma from the rabbit reticulocyte eukaryotic initiation factor 2.

Q9Y7J6	PPK21_SCHPO	Serine/threonine-protein kinase ppk21	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q6A028	SWP70_MOUSE	Switch-associated protein 70	9642267	A B-cell-specific DNA recombination complex.

P36583	PCK2_SCHPO	Protein kinase C-like 2	8491190	Two novel protein kinase C-related genes of fission yeast are essential for cell viability and implicated in cell shape control.

Q60749	KHDR1_MOUSE	KH domain-containing, RNA-binding, signal transduction-associated protein 1	12529443	Sam68 RNA binding protein is an in vivo substrate for protein arginine N-methyltransferase 1.

O95257	GA45G_HUMAN	Growth arrest and DNA damage-inducible protein GADD45 gamma	12716909	CR6-interacting factor 1 interacts with Gadd45 family proteins and modulates the cell cycle.

O43704	ST1B1_HUMAN	Sulfotransferase family cytosolic 1B member 1	9443824	Molecular cloning and characterization of rat ST1B1 and human ST1B2 cDNAs, encoding thyroid hormone sulfotransferases.

P14735	IDE_HUMAN	Insulin-degrading enzyme	2293021	Insulin-degrading enzyme: stable expression of the human complementary DNA, characterization of its protein product, and chromosomal mapping of the human and mouse genes.

Q9ULG1	INO80_HUMAN	Putative DNA helicase INO80 complex homolog 1	16298340	Characterization of a human SWI2/SNF2 like protein hINO80: demonstration of catalytic and DNA binding activity.

O16519	GAD1_CAEEL	Gastrulation defective protein 1	9659931	Gastrulation initiation in Caenorhabditis elegans requires the function of gad-1, which encodes a protein with WD repeats.

Q9U5W9	TAF10_DROME	Transcription initiation factor TFIID subunit 10	10669741	Two novel Drosophila TAFIIs have homology with human TAFII30 and are differentially regulated during development.

O94694	YG1A_SCHPO	UPF0620 protein C83.10	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9P2Y5	UVRAG_HUMAN	UV radiation resistance-associated gene protein	9169138	Molecular cloning of a novel human gene encoding a 63-kDa protein and its sublocalization within the 11q13 locus.

Q93ZH0	LYM1_ARATH	LysM domain-containing GPI-anchored protein 1	12805588	Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis.

Q94AA4	K6PF3_ARATH	6-phosphofructokinase 3	17485088	Characterisation of the ATP-dependent phosphofructokinase gene family from Arabidopsis thaliana.

P10983	ACT1_CAEEL	Actin-1/3	12732734	The structure of nonvertebrate actin: implications for the ATP hydrolytic mechanism.

P98170	XIAP_HUMAN	Baculoviral IAP repeat-containing protein 4	9230442	X-linked IAP is a direct inhibitor of cell-death proteases.

P10636	TAU_HUMAN	Microtubule-associated protein tau	15953362	Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation.

Q14789	GOGB1_HUMAN	Golgin subfamily B member 1	8198703	Macrogolgin -- a new 376 kD Golgi complex outer membrane protein as target of antibodies in patients with rheumatic diseases and HIV infections.

Q4PIR3	NSE2_SCHPO	E3 SUMO-protein ligase nse2	15601841	Nse2, a component of the Smc5-6 complex, is a SUMO ligase required for the response to DNA damage.

P52952	NKX25_HUMAN	Homeobox protein Nkx-2.5	16418214	Missense mutation in the transcription factor NKX2-5: a novel molecular event in the pathogenesis of thyroid dysgenesis.

Q9ULB5	CADH7_HUMAN	Cadherin-7	10861224	Identification of three human type-II classic cadherins and frequent heterophilic interactions between different subclasses of type-II classic cadherins.

O13958	SSN3_SCHPO	Serine/threonine-protein kinase prk1	12738880	TRAP230/ARC240 and TRAP240/ARC250 Mediator subunits are functionally conserved through evolution.

P97636	IL18_RAT	Interleukin-18	8999896	Induction of interferon-gamma inducing factor in the adrenal cortex.

P54219	VMAT1_HUMAN	Chromaffin granule amine transporter	8643547	Distinct pharmacological properties and distribution in neurons and endocrine cells of two isoforms of the human vesicular monoamine transporter.

Q9CRB9	CHCH3_MOUSE	Coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial	14651853	Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.

P11142	HSP7C_HUMAN	Heat shock cognate 71 kDa protein	11093761	Molecular and functional characterization of HSC54, a novel variant of human heat shock cognate protein 70.

P08138	TNR16_HUMAN	Tumor necrosis factor receptor superfamily member 16	14966521	LINGO-1 is a component of the Nogo-66 receptor/p75 signaling complex.

Q7Z3B3	K1267_HUMAN	MLL1/MLL complex subunit KIAA1267	15960975	Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

Q10953	WRM1_CAEEL	Armadillo repeat-containing protein wrm-1	16077003	Asymmetric cortical and nuclear localizations of WRM-1/beta-catenin during asymmetric cell division in C. elegans.

P78953	DMF1_SCHPO	Division mal foutue 1 protein	8946912	The dmf1/mid1 gene is essential for correct positioning of the division septum in fission yeast.

Q9ET78	JPH2_MOUSE	Junctophilin-2	10949023	Junctophilins: a novel family of junctional membrane complex proteins.

P54886	P5CS_HUMAN	Delta-1-pyrroline-5-carboxylate synthase	10037775	Molecular enzymology of mammalian delta1-pyrroline-5-carboxylate synthase. Alternative splice donor utilization generates isoforms with different sensitivity to ornithine inhibition.

P83294	GR64B_DROME	Putative gustatory receptor 64b	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

Q6EJB6	UT14B_MOUSE	U3 small nucleolar RNA-associated protein 14 homolog B	15258580	An X-to-autosome retrogene is required for spermatogenesis in mice.

Q55DM1	LVSA_DICDI	BEACH domain-containing protein lvsA	11865029	Two members of the beige/CHS (BEACH) family are involved at different stages in the organization of the endocytic pathway in Dictyostelium.

Q9U1N0	HRP65_CHITE	Hrp65 protein	11262185	Molecular characterization of Ct-hrp65: identification of two novel isoforms originated by alternative splicing.

P93834	HXK2_ARATH	Hexokinase-2	16920781	Mitochondria-associated hexokinases play a role in the control of programmed cell death in Nicotiana benthamiana.

Q9LU85	PAP4_ARATH	Probable plastid-lipid-associated protein 4, chloroplastic	16414959	Tocopherol cyclase (VTE1) localization and vitamin E accumulation in chloroplast plastoglobule lipoprotein particles.

O43847	NRDC_HUMAN	Nardilysin	9581555	Human and rat testis express two mRNA species encoding variants of NRD convertase, a metalloendopeptidase of the insulinase family.

P83687	PSBP_EUGGR	Oxygen-evolving enhancer protein 2	12837550	Cytochrome f and subunit IV, two essential components of the photosynthetic bf complex typically encoded in the chloroplast genome, are nucleus-encoded in Euglena gracilis.

P58953	GR22E_DROME	Putative gustatory receptor 22e	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

O95551	TYDP2_HUMAN	Tyrosyl-DNA phosphodiesterase 2	10764746	TTRAP, a novel protein that associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor-associated factors (TRAFs), and that inhibits nuclear factor-kappa B activation.

Q9WTN3	SRBP1_MOUSE	Sterol regulatory element-binding protein 1	9329978	Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene.

O60662	KBTBA_HUMAN	Kelch repeat and BTB domain-containing protein 10	9655184	DNA sequence and muscle-specific expression of human sarcosin transcripts.

O15342	VA0E1_HUMAN	V-type proton ATPase subunit e 1	9556572	Identification and characterization of a novel 9.2-kDa membrane sector-associated protein of vacuolar proton-ATPase from chromaffin granules.

P08588	ADRB1_HUMAN	Beta-1 adrenergic receptor	10212248	A gain-of-function polymorphism in a G-protein coupling domain of the human beta1-adrenergic receptor.

Q7Z2C4	SELG_DROME	Glycine-rich selenoprotein	11493597	In silico identification of novel selenoproteins in the Drosophila melanogaster genome.

Q04429	HLR1_YEAST	Protein HLR1	11532139	Hyperosmotic stress response and regulation of cell wall integrity in Saccharomyces cerevisiae share common functional aspects.

P59759	MKL2_MOUSE	MKL/myocardin-like protein 2	12397177	Potentiation of serum response factor activity by a family of myocardin-related transcription factors.

P36417	GBF_DICDI	G-box-binding factor	8125261	Cloning and characterization of the G-box binding factor, an essential component of the developmental switch between early and late development in Dictyostelium.

Q9SZ11	GLPQ2_ARATH	Probable glycerophosphoryl diester phosphodiesterase 2	12805588	Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis.

Q8VIJ5	NCOAT_RAT	Bifunctional protein NCOAT	15485860	Characterization of the histone acetyltransferase (HAT) domain of a bifunctional protein with activable O-GlcNAcase and HAT activities.

Q09094	REC15_SCHPO	Meiotic recombination protein rec15	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9D9J7	IZUM1_MOUSE	Izumo sperm-egg fusion protein 1	15759005	The immunoglobulin superfamily protein Izumo is required for sperm to fuse with eggs.

Q9XTN2	IRS1_DROME	Insulin receptor substrate 1	11292874	Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein.

B5BUZ8	PF13_CHLRE	Protein kintoun	19052621	Ktu/PF13 is required for cytoplasmic pre-assembly of axonemal dyneins.

Q8NFH4	NUP37_HUMAN	Nucleoporin Nup37	15146057	The entire Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis.

Q60809	CNOT7_MOUSE	CCR4-NOT transcription complex subunit 7	7791755	Identification of a mouse protein whose homolog in Saccharomyces cerevisiae is a component of the CCR4 transcriptional regulatory complex.

P23572	CDK1_DROME	Cell division protein kinase 1	8223248	Genetic analysis of the Drosophila cdc2 homolog.

Q94901	LARK_DROME	RNA-binding protein lark	9491990	A molecular rhythm mediating circadian clock output in Drosophila.

P97303	BACH2_MOUSE	Transcription regulator protein BACH2	8887638	Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site.

P51610	HCFC1_HUMAN	Host cell factor 1	10675337	The novel coactivator C1 (HCF) coordinates multiprotein enhancer formation and mediates transcription activation by GABP.

Q5H8C4	VP13A_MOUSE	Vacuolar protein sorting-associated protein 13A	15686477	A gene-targeted mouse model for chorea-acanthocytosis.

Q24188	LBM_DROME	Protein late bloomer	8596956	A neural tetraspanin, encoded by late bloomer, that facilitates synapse formation.

P0CG30	GSTT2_HUMAN	Glutathione S-transferase theta-2B	7789971	Molecular cloning of a cDNA and chromosomal localization of a human theta-class glutathione S-transferase gene (GSTT2) to chromosome 22.

P13231	HATA_DICDI	Hisactophilin-1	7822284	The pH-sensitive actin-binding protein hisactophilin of Dictyostelium exists in two isoforms which both are myristoylated and distributed between plasma membrane and cytoplasm.

O74478	PGM2_SCHPO	Phosphoglucomutase-2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P80217	IN35_HUMAN	Interferon-induced 35 kDa protein	8954125	IFP 35 forms complexes with B-ATF, a member of the AP1 family of transcription factors.

Q03530	RCE1_YEAST	CAAX prenyl protease 2	9065405	Modulation of Ras and a-factor function by carboxyl-terminal proteolysis.

O14832	PAHX_HUMAN	Phytanoyl-CoA dioxygenase, peroxisomal	9326939	Identification of PAHX, a Refsum disease gene.

O80963	ACCR2_ARATH	Serine/threonine-protein kinase-like protein CCR2	18539132	Dimerization properties of the transmembrane domains of Arabidopsis CRINKLY4 receptor-like kinase and homologs.

Q9W590	LSG1_DROME	Large subunit GTPase 1 homolog	18628395	A nucleostemin family GTPase, NS3, acts in serotonergic neurons to regulate insulin signaling and control body size.

P53950	VAC7_YEAST	Vacuolar segregation protein 7	9372916	Vac7p, a novel vacuolar protein, is required for normal vacuole inheritance and morphology.

Q63081	PDIA6_RAT	Protein disulfide-isomerase A6	7876340	CaBP1, a calcium binding protein of the thioredoxin family, is a resident KDEL protein of the ER and not of the intermediate compartment.

P42704	LPPRC_HUMAN	Leucine-rich PPR motif-containing protein, mitochondrial	12832482	LRP130, a pentatricopeptide motif protein with a noncanonical RNA- binding domain, is bound in vivo to mitochondrial and nuclear RNAs.

Q95P08	HCYA_SCUCO	Hemocyanin subunit A	12823556	Complete subunit sequences, structure and evolution of the 6 x 6-mer hemocyanin from the common house centipede, Scutigera coleoptrata.

O15344	TRI18_HUMAN	Midline-1	9354791	Opitz G/BBB syndrome, a defect of midline development, is due to mutations in a new RING finger gene on Xp22.

P57744	TIM8_YEAST	Mitochondrial import inner membrane translocase subunit TIM8	10469659	Different import pathways through the mitochondrial intermembrane space for inner membrane proteins.

P62314	SMD1_HUMAN	Small nuclear ribonucleoprotein Sm D1	3260384	Molecular cloning of a cDNA encoding the human Sm-D autoantigen.

Q9QXS8	CMLO5_MOUSE	Probable N-acetyltransferase CML5	11397015	Overexpression of camello, a member of a novel protein family, reduces blastomere adhesion and inhibits gastrulation in Xenopus laevis.

P03871	REP1_YEAST	Partitioning protein REP1	9393716	The 2 micrometer-plasmid-encoded Rep1 and Rep2 proteins interact with each other and colocalize to the Saccharomyces cerevisiae nucleus.

P28576	PDGFA_RAT	Platelet-derived growth factor subunit A	8447423	Increased expression of PDGF A- and B-chain genes in rat lungs with hypoxic pulmonary hypertension.

Q9GZM8	NDEL1_HUMAN	Nuclear distribution protein nudE-like 1	17600710	Cenp-F links kinetochores to Ndel1/Nde1/Lis1/dynein microtubule motor complexes.

Q08496	DIA2_YEAST	Protein DIA2	11063681	Genetic analysis reveals that FLO11 upregulation and cell polarization independently regulate invasive growth in Saccharomyces cerevisiae.

Q9SLG3	ZIP3_ARATH	Zinc transporter 3	9618566	Identification of a family of zinc transporter genes from Arabidopsis that respond to zinc deficiency.

Q99895	CTRC_HUMAN	Chymotrypsin-C	8635596	Molecular cloning and expression of human caldecrin.

Q96QR1	SG3A1_HUMAN	Secretoglobin family 3A member 1	11481438	HIN-1, a putative cytokine highly expressed in normal but not cancerous mammary epithelial cells.

Q9TVM2	XPO1_DROME	Exportin-1	10924475	The Drosophila embargoed gene is required for larval progression and encodes the functional homolog of Schizosaccharomyces Crm1.

Q9H8S9	MOL1B_HUMAN	Mps one binder kinase activator-like 1B	19739119	Molecular characterization of human homologs of yeast MOB1.

Q9FFH6	FLA13_ARATH	Fasciclin-like arabinogalactan protein 13	14517339	Proteomic analysis of glycosylphosphatidylinositol-anchored membrane proteins.

Q8BP00	IQCB1_MOUSE	IQ calmodulin-binding motif-containing protein 1	15723066	Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior- Loken syndrome and interacts with RPGR and calmodulin.

Q24248	ARA_DROME	Homeobox protein araucan	8620542	Araucan and caupolican, two members of the novel iroquois complex, encode homeoproteins that control proneural and vein-forming genes.

O93529	FOXB1_XENLA	Forkhead box protein B1	11404077	Early anteroposterior division of the presumptive neurectoderm in Xenopus.

Q9Y239	NOD1_HUMAN	Nucleotide-binding oligomerization domain-containing protein 1	10329646	Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor- kappaB.

P48559	YPT11_YEAST	GTP-binding protein YPT11	11785952	Saccharomyces cerevisiae Pra1p/Yip3p interacts with Yip1p and Rab proteins.

P36053	ELF1_YEAST	Transcription elongation factor 1	14562095	Global analysis of protein localization in budding yeast.

P48643	TCPE_HUMAN	T-complex protein 1 subunit epsilon	16548883	Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection.

P08631	HCK_HUMAN	Tyrosine-protein kinase HCK	11278465	The tyrosine kinase Hck is an inhibitor of HIV-1 replication counteracted by the viral vif protein.

Q55DR6	FCSA_DICDI	Fatty acyl-CoA synthetase A	14629118	A Dictyostelium long chain fatty acyl coenzyme A-synthetase mediates fatty acid retrieval from endosomes.

P00564	KCRM_RAT	Creatine kinase M-type	6209281	Isolation and sequence analysis of cDNA clones coding for rat skeletal muscle creatine kinase.

O94462	PUF3_SCHPO	mRNA-binding protein puf3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P49893	WN11B_XENLA	Protein Wnt-11b	18809723	Ryk cooperates with Frizzled 7 to promote Wnt11-mediated endocytosis and is essential for Xenopus laevis convergent extension movements.

Q02388	CO7A1_HUMAN	Collagen alpha-1(VII) chain	19269366	TANGO1 facilitates cargo loading at endoplasmic reticulum exit sites.

P04181	OAT_HUMAN	Ornithine aminotransferase, mitochondrial	2793865	Point mutation affecting processing of the ornithine aminotransferase precursor protein in gyrate atrophy.

Q92911	SC5A5_HUMAN	Sodium/iodide cotransporter	8806637	Cloning of the human sodium iodide symporter.

Q01955	CO4A3_HUMAN	Collagen alpha-3(IV) chain	10212244	Characterization of a novel type of serine/threonine kinase that specifically phosphorylates the human goodpasture antigen.

O14508	SOCS2_HUMAN	Suppressor of cytokine signaling 2	9727029	Interaction of human suppressor of cytokine signaling (SOCS)-2 with the insulin-like growth factor-I receptor.

P36775	LONM_YEAST	Lon protease homolog, mitochondrial	8146662	Requirement for the yeast gene LON in intramitochondrial proteolysis and maintenance of respiration.

Q15596	NCOA2_HUMAN	Nuclear receptor coactivator 2	9430642	The coactivator TIF2 contains three nuclear receptor-binding motifs and mediates transactivation through CBP binding-dependent and -independent pathways.

O75150	BRE1B_HUMAN	E3 ubiquitin-protein ligase BRE1B	10944455	RBP95, a novel leucine zipper protein, binds to the retinoblastoma protein.

Q9Y5H7	PCDA5_HUMAN	Protocadherin alpha-5	10380929	A striking organization of a large family of human neural cadherin- like cell adhesion genes.

Q8C8R3	ANK2_MOUSE	Ankyrin-2	19007774	Ankyrin-B is required for coordinated expression of beta-2-spectrin, the Na/K-ATPase and the Na/Ca exchanger in the inner segment of rod photoreceptors.

Q86UR1	NOXA1_HUMAN	NADPH oxidase activator 1	16636067	Nox1-dependent reactive oxygen generation is regulated by Rac1.

P26786	RS7A_YEAST	40S ribosomal protein S7-A	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q9Z1D1	EIF3G_MOUSE	Eukaryotic translation initiation factor 3 subunit G	17581632	Reconstitution reveals the functional core of mammalian eIF3.

Q99KS2	NGRN_MOUSE	Neugrin	11118320	Two novel genes, human neugrin and mouse m-neugrin, are upregulated with neuronal differentiation in neuroblastoma cells.

Q04431	YD532_YEAST	Spindle pole body component YDR532C	14565975	Interactions between centromere complexes in Saccharomyces cerevisiae.

P19338	NUCL_HUMAN	Nucleolin	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

Q9JKS4	LDB3_MOUSE	LIM domain-binding protein 3	10391924	Cypher, a striated muscle-restricted PDZ and LIM domain-containing protein, binds to alpha-actinin-2 and protein kinase C.

P31643	SC6A6_RAT	Sodium- and chloride-dependent taurine transporter	1435737	Cloning and expression of a high affinity taurine transporter from rat brain.

Q5XXP2	OPN4_PHOSU	Melanopsin	15698924	Predicted 3D-structure of melanopsin, the non-rod, non-cone photopigment of the mammalian circadian clock, from Djungarian hamsters (Phodopus sungorus).

Q9FLW0	Y5241_ARATH	Probable receptor-like protein kinase At5g24010	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q9CR14	FANCL_MOUSE	E3 ubiquitin-protein ligase FANCL	12574169	Mouse GGN1 and GGN3, two germ cell-specific proteins from the single gene Ggn, interact with mouse POG and play a role in spermatogenesis.

P34021	ECR_DROME	Ecdysone receptor	8324824	Drosophila tissues with different metamorphic responses to ecdysone express different ecdysone receptor isoforms.

Q9H0M0	WWP1_HUMAN	NEDD4-like E3 ubiquitin-protein ligase WWP1	19580544	Endogenous spartin (SPG20) is recruited to endosomes and lipid droplets and interacts with the ubiquitin E3 ligases AIP4 and AIP5.

Q9ZWC5	SCL18_ARATH	Scarecrow-like protein 18	12730136	Molecular analysis of the LATERAL SUPPRESSOR gene in Arabidopsis reveals a conserved control mechanism for axillary meristem formation.

Q9FYE1	MCA9_ARATH	Metacaspase-9	15326173	Type II metacaspases Atmc4 and Atmc9 of Arabidopsis thaliana cleave substrates after arginine and lysine.

Q9W0Y8	SCN60_DROME	Sodium channel protein 60E	12196396	The DSC1 channel, encoded by the smi60E locus, contributes to odor- guided behavior in Drosophila melanogaster.

Q9UBT3	DKK4_HUMAN	Dickkopf-related protein 4	10570958	Functional and structural diversity of the human Dickkopf gene family.

P12687	RM02_YEAST	54S ribosomal protein L2, mitochondrial	12392552	Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components.

P12272	PTHR_HUMAN	Parathyroid hormone-related protein	2708388	Characterization of the human parathyroid hormone-like peptide gene. Functional and evolutionary aspects.

Q9UTM2	CO111_SCHPO	Rsm22-cox11 tandem protein 1, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P11274	BCR_HUMAN	Breakpoint cluster region protein	1657398	The BCR gene encodes a novel serine/threonine kinase activity within a single exon.

P25100	ADA1D_HUMAN	Alpha-1D adrenergic receptor	1656955	Molecular cloning and sequencing of a cDNA encoding a human alpha 1A adrenergic receptor.

Q06485	ATG33_YEAST	Autophagy-related protein 33	14562095	Global analysis of protein localization in budding yeast.

Q58F21	BRDT_HUMAN	Bromodomain testis-specific protein	9367677	Identification and characterization of BRDT: a testis-specific gene related to the bromodomain genes RING3 and Drosophila fsh.

Q923Z4	FER3L_MOUSE	Fer3-like protein	12217327	N-twist, an evolutionarily conserved bHLH protein expressed in the developing CNS, functions as a transcriptional inhibitor.

Q9HCR9	PDE11_HUMAN	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	10725373	Molecular cloning and characterization of a distinct human phosphodiesterase gene family: PDE11A.

Q812A3	ANR23_MOUSE	Ankyrin repeat domain-containing protein 23	12456686	Molecular identification and characterization of a novel nuclear protein whose expression is up-regulated in insulin-resistant animals.

Q63881	KCND2_RAT	Potassium voltage-gated channel subfamily D member 2	14980206	Structural insights into the functional interaction of KChIP1 with Shal-type K(+) channels.

O94762	RECQ5_HUMAN	ATP-dependent DNA helicase Q5	10710432	Human RecQ5-beta, a large isomer of RecQ5 DNA helicase, localizes in the nucleoplasm and interacts with topoisomerases 3-alpha and 3- beta.

P42658	DPP6_HUMAN	Dipeptidyl aminopeptidase-like protein 6	8103397	Non-conservation of a catalytic residue in a dipeptidyl aminopeptidase IV-related protein encoded by a gene on human chromosome 7.

P06401	PRGR_HUMAN	Progesterone receptor	12917342	BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation.

P25724	NANOS_DROME	Protein nanos	11274060	Drosophila Brain tumor is a translational repressor.

Q9Y103	TFP11_DROME	Septin-interacting protein 1	11884525	Identification of septin-interacting proteins and characterization of the Smt3/SUMO-conjugation system in Drosophila.

O95786	DDX58_HUMAN	Probable ATP-dependent RNA helicase DDX58	17190814	Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2.

Q03694	INP1_YEAST	Inheritance of peroxisomes protein 1	14562095	Global analysis of protein localization in budding yeast.

Q24572	CAF1_DROME	Probable histone-binding protein Caf1	8887645	The p55 subunit of Drosophila chromatin assembly factor 1 is homologous to a histone deacetylase-associated protein.

P30084	ECHM_HUMAN	Enoyl-CoA hydratase, mitochondrial	9073515	Human mitochondrial enoyl-CoA hydratase gene (ECHS1): structural organization and assignment to chromosome 10q26.2-q26.3.

Q14BU0	UCMA_MOUSE	Unique cartilage matrix-associated protein	18156182	Ucma, a novel secreted cartilage-specific protein with implications in osteogenesis.

Q08905	FRE3_YEAST	Ferric reductase transmembrane component 3	9726978	Metalloregulation of FRE1 and FRE2 homologs in Saccharomyces cerevisiae.

P69851	DAD4_YEAST	DASH complex subunit DAD4	15664196	Formation of a dynamic kinetochore-microtubule interface through assembly of the Dam1 ring complex.

P93022	ARFG_ARATH	Auxin response factor 7	15659631	Functional genomic analysis of the AUXIN RESPONSE FACTOR gene family members in Arabidopsis thaliana: unique and overlapping functions of ARF7 and ARF19.

Q05610	DON1_YEAST	Donuts protein 1	11973299	Ady3p links spindle pole body function to spore wall synthesis in Saccharomyces cerevisiae.

Q8K3B1	FBSP1_MOUSE	F-box/SPRY domain-containing protein 1	19996097	Fbxo45, a novel ubiquitin ligase, regulates synaptic activity.

P29066	ARRB1_RAT	Beta-arrestin-1	11742073	beta-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins.

Q8IVT5	KSR1_HUMAN	Kinase suppressor of Ras 1	8521512	KSR, a novel protein kinase required for RAS signal transduction.

Q03001	BPA1_HUMAN	Bullous pemphigoid antigen 1	11751855	Novel alternative splicings of BPAG1 (bullous pemphigoid antigen 1) including the domain structure closely related to MACF (microtubule actin cross-linking factor).

Q13114	TRAF3_HUMAN	TNF receptor-associated factor 3	12005438	Downstream regulator TANK binds to the CD40 recognition site on TRAF3.

P0C1G9	SOX11_RAT	Transcription factor SOX-11	9632656	Cooperative function of POU proteins and SOX proteins in glial cells.

Q8UVJ6	VANG2_DANRE	Vang-like protein 2	11780127	The planar cell-polarity gene stbm regulates cell behaviour and cell fate in vertebrate embryos.

P46971	PMT4_YEAST	Dolichyl-phosphate-mannose--protein mannosyltransferase 4	8585318	PMT3 and PMT4, two new members of the protein-O-mannosyltransferase gene family of Saccharomyces cerevisiae.

Q15910	EZH2_HUMAN	Histone-lysine N-methyltransferase EZH2	15385962	Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity.

P08536	MET3_YEAST	Sulfate adenylyltransferase	14562095	Global analysis of protein localization in budding yeast.

Q8IY92	SLX4_HUMAN	Structure-specific endonuclease subunit SLX4	19595721	Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair.

Q9NRX2	RM17_HUMAN	39S ribosomal protein L17, mitochondrial	11984006	The Chediak-Higashi protein interacts with SNARE complex and signal transduction proteins.

Q12167	YD065_YEAST	Uncharacterized protein YDR065W	14562095	Global analysis of protein localization in budding yeast.

O75388	GPR32_HUMAN	Probable G-protein coupled receptor 32	9653656	Cloning genes encoding receptors related to chemoattractant receptors.

Q96BR1	SGK3_HUMAN	Serine/threonine-protein kinase Sgk3	10585774	Cloning and mapping of a novel human Serum/Glucocorticoid regulated kinase-like gene, SGKL, to chromosome 8q12.3-q13.1.

O43318	M3K7_HUMAN	Mitogen-activated protein kinase kinase kinase 7	12874243	Pellino3, a novel member of the Pellino protein family, promotes activation of c-Jun and Elk-1 and may act as a scaffolding protein.

P31369	PDM2A_DROME	POU domain protein 2, isoform A	1496003	dOct2, a Drosophila Oct transcription factor that functions in yeast.

O49484	ASK11_ARATH	SKP1-like protein 11	19682297	An F-box gene, CPR30, functions as a negative regulator of the defense response in Arabidopsis.

Q9BXJ9	NAA15_HUMAN	N-alpha-acetyltransferase 15, NatA auxiliary subunit	12140756	NATH, a novel gene overexpressed in papillary thyroid carcinomas.

P07263	SYH_YEAST	Histidyl-tRNA synthetase, mitochondrial	1459448	HTS1 encodes both the cytoplasmic and mitochondrial histidyl-tRNA synthetase of Saccharomyces cerevisiae: mutations alter the specificity of compartmentation.

Q04659	CSM3_YEAST	Chromosome segregation in meiosis protein 3	16418273	The Tof1p-Csm3p protein complex counteracts the Rrm3p helicase to control replication termination of Saccharomyces cerevisiae.

Q5MFV8	PME5_ARATH	Pectinesterase 5	15659637	VANGUARD1 encodes a pectin methylesterase that enhances pollen tube growth in the Arabidopsis style and transmitting tract.

P69451	LCFA_ECOLI	Long-chain-fatty-acid--CoA ligase	12034706	Functional role of fatty acyl-coenzyme A synthetase in the transmembrane movement and activation of exogenous long-chain fatty acids. Amino acid residues within the ATP/AMP signature motif of Escherichia coli FadD are required for enzyme activity and fatty acid transport.

P35438	NMDZ1_MOUSE	Glutamate [NMDA] receptor subunit zeta-1	1532151	Cloning, expression and modulation of a mouse NMDA receptor subunit.

Q9PUN2	SMUF1_XENLA	E3 ubiquitin-protein ligase SMURF1	10458166	A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation.

Q91372	DDX4_XENLA	Probable ATP-dependent RNA helicase DDX4	10830432	Spatio-temporal expression of Xenopus vasa homolog, XVLG1, in oocytes and embryos: the presence of XVLG1 RNA in somatic cells as well as germline cells.

Q12864	CAD17_HUMAN	Cadherin-17	8153632	Association of intestinal peptide transport with a protein related to the cadherin superfamily.

P25008	CCNC_DROME	Cyclin-C	17290221	Distinct roles for Mediator Cdk8 module subunits in Drosophila development.

P80192	M3K9_HUMAN	Mitogen-activated protein kinase kinase kinase 9	15610029	Phosphoregulation of mixed-lineage kinase 1 activity by multiple phosphorylation in the activation loop.

P52743	ZN137_HUMAN	Zinc finger protein 137	7557990	Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders.

O94911	ABCA8_HUMAN	ATP-binding cassette sub-family A member 8	12379217	Functional analysis of ABCA8, a new drug transporter.

Q39214	RPM1_ARATH	Disease resistance protein RPM1	9861059	The Arabidopsis thaliana RPM1 disease resistance gene product is a peripheral plasma membrane protein that is degraded coincident with the hypersensitive response.

P49441	INPP_HUMAN	Inositol polyphosphate 1-phosphatase	8390685	Cloning, heterologous expression, and chromosomal localization of human inositol polyphosphate 1-phosphatase.

Q09470	KCNA1_HUMAN	Potassium voltage-gated channel subfamily A member 1	8845167	Episodic ataxia results from voltage-dependent potassium channels with altered functions.

Q6WKZ8	UBR2_MOUSE	E3 ubiquitin-protein ligase UBR2	14585983	Female lethality and apoptosis of spermatocytes in mice lacking the UBR2 ubiquitin ligase of the N-end rule pathway.

Q99188	RGS2_YEAST	Regulator of G-protein signaling 2	14562095	Global analysis of protein localization in budding yeast.

Q3L8U1	CHD9_HUMAN	Chromodomain-helicase-DNA-binding protein 9	16554032	PRIC320, a transcription coactivator, isolated from peroxisome proliferator-binding protein complex.

P52643	LDHD_ECOLI	D-lactate dehydrogenase	8349564	Characterization of twenty-six new heat shock genes of Escherichia coli.

Q94464	DYNA_DICDI	Dynamin-A	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P10912	GHR_HUMAN	Growth hormone receptor	2825030	Growth hormone receptor and serum binding protein: purification, cloning and expression.

P98187	CP4F8_HUMAN	Cytochrome P450 4F8	10405341	Gene expression of a novel cytochrome P450 of the CYP4F subfamily in human seminal vesicles.

Q9ET77	JPH3_MOUSE	Junctophilin-3	11906164	Motor discoordination in mutant mice lacking junctophilin type 3.

Q08157	YOL19_YEAST	Uncharacterized membrane protein YOL019W	14562095	Global analysis of protein localization in budding yeast.

Q04779	RCO1_YEAST	Transcriptional regulatory protein RCO1	14562095	Global analysis of protein localization in budding yeast.

Q9PU13	SPD1A_XENLA	Speedy protein 1-A	10465793	A novel p34cdc2 binding and activating protein that is necessary and sufficient to trigger G2/M progression in Xenopus oocytes.

Q8LGA5	ATL31_ARATH	E3 ubiquitin-protein ligase ATL31	19702666	CNI1/ATL31, a RING-type ubiquitin ligase that functions in the carbon/nitrogen response for growth phase transition in Arabidopsis seedlings.

P42529	CBPA_DICDI	Calcium-binding protein A	7729526	Cloning and expression in Escherichia coli of a cDNA encoding a developmentally regulated Ca(2+)-binding protein from Dictyostelium discoideum.

O70299	MB211_MOUSE	Protein mab-21-like 1	10556287	Two murine and human homologs of mab-21, a cell fate determination gene involved in Caenorhabditis elegans neural development.

P38791	DHYS_YEAST	Deoxyhypusine synthase	7629166	Identification of YHR068w in Saccharomyces cerevisiae chromosome VIII as a gene for deoxyhypusine synthase. Expression and characterization of the enzyme.

Q9CZL5	PHS2_MOUSE	Pterin-4-alpha-carbinolamine dehydratase 2	15182178	Biochemical and structural basis for partially redundant enzymatic and transcriptional functions of DCoH and DCoH2.

P25569	GID7_YEAST	Glucose-induced degradation protein 7	14562095	Global analysis of protein localization in budding yeast.

Q9SCX8	PPA17_ARATH	Purple acid phosphatase 17	10504579	A type 5 acid phosphatase gene from Arabidopsis thaliana is induced by phosphate starvation and by some other types of phosphate mobilising/oxidative stress conditions.

O42953	YGM4_SCHPO	HMG box-containing protein C19G7.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9SD84	E13L3_ARATH	Glucan endo-1,3-beta-glucosidase-like protein 3	14517339	Proteomic analysis of glycosylphosphatidylinositol-anchored membrane proteins.

P46467	VPS4B_MOUSE	Vacuolar protein sorting-associated protein 4B	12594041	Comparative sequence and expression analyses of four mammalian VPS4 genes.

Q09353	SENP_CAEEL	Sentrin-specific protease	15107848	SUMO modification is required for in vivo Hox gene regulation by the Caenorhabditis elegans Polycomb group protein SOP-2.

Q92572	AP3S1_HUMAN	AP-3 complex subunit sigma-1	9118953	AP-3: an adaptor-like protein complex with ubiquitous expression.

O70260	PIAS3_RAT	E3 SUMO-protein ligase PIAS3	9565597	Cloning and expression of a novel K+ channel regulatory protein, KChAP.

P82872	TO201_ARATH	Mitochondrial import receptor subunit TOM20-1	11161051	Purification and characterization of the preprotein translocase of the outer mitochondrial membrane from Arabidopsis. Identification of multiple forms of TOM20.

P10636	TAU_HUMAN	Microtubule-associated protein tau	10747907	Interaction of tau with the neural membrane cortex is regulated by phosphorylation at sites that are modified in paired helical filaments.

Q76I89	NDC80_CHICK	Kinetochore protein NDC80 homolog	12829748	Dynamic behavior of Nuf2-Hec1 complex that localizes to the centrosome and centromere and is essential for mitotic progression in vertebrate cells.

P29506	UNC4_CAEEL	Homeobox protein unc-4	11245684	Regulation of neurotransmitter vesicles by the homeodomain protein UNC-4 and its transcriptional corepressor UNC-37/groucho in Caenorhabditis elegans cholinergic motor neurons.

Q9ZU90	SKI28_ARATH	F-box protein SKIP28	15634699	Genetic and molecular identification of genes required for female gametophyte development and function in Arabidopsis.

Q7M725	TR107_MOUSE	Taste receptor type 2 member 107	11854532	Expression of bitter taste receptors of the T2R family in the gastrointestinal tract and enteroendocrine STC-1 cells.

Q9FQ09	KU80_ARATH	ATP-dependent DNA helicase 2 subunit KU80	18515112	Regulation of Arabidopsis thaliana Ku genes at different developmental stages under heat stress.

Q9Y5I7	CLD16_HUMAN	Claudin-16	10390358	Paracellin-1, a renal tight junction protein required for paracellular Mg2+ resorption.

P49711	CTCF_HUMAN	Transcriptional repressor CTCF	16949368	CTCF-dependent chromatin insulator is linked to epigenetic remodeling.

P84022	SMAD3_HUMAN	Mothers against decapentaplegic homolog 3	17099224	Potentiation of Smad-mediated transcriptional activation by the RNA- binding protein RBPMS.

Q9YHC5	FOXG1_XENLA	Forkhead box protein G1	10683182	Distinct effects of XBF-1 in regulating the cell cycle inhibitor p27(XIC1) and imparting a neural fate.

Q925H0	ACCN1_MOUSE	Amiloride-sensitive cation channel 1, neuronal	11306621	Transport and localization of the DEG/ENaC ion channel BNaC1alpha to peripheral mechanosensory terminals of dorsal root ganglia neurons.

P51784	UBP11_HUMAN	Ubiquitin carboxyl-terminal hydrolase 11	15314155	BRCA2 is ubiquitinated in vivo and interacts with USP11, a deubiquitinating enzyme that exhibits prosurvival function in the cellular response to DNA damage.

P09668	CATH_HUMAN	Cathepsin H	2587265	Nucleotide sequence of human preprocathepsin H, a lysosomal cysteine proteinase.

P30681	HMGB2_MOUSE	High mobility group protein B2	7720710	High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors.

Q22720	GAP1_CAEEL	Ras GTPase-activating protein gap-1	9334333	Inhibition of Caenorhabditis elegans vulval induction by gap-1 and by let-23 receptor tyrosine kinase.

P14242	PMS1_YEAST	DNA mismatch repair protein PMS1	14562095	Global analysis of protein localization in budding yeast.

O14981	BTAF1_HUMAN	TATA-binding protein-associated factor 172	9488487	Cloning and biochemical characterization of TAF-172, a human homolog of yeast Mot1.

P11632	NHP6A_YEAST	Non-histone chromosomal protein 6A	11432837	Spt16-Pob3 and the HMG protein Nhp6 combine to form the nucleosome- binding factor SPN.

Q6UUV9	CRTC1_HUMAN	CREB-regulated transcription coactivator 1	14506290	Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells.

P50086	PSD10_YEAST	Probable 26S proteasome regulatory subunit p28	19446322	Multiple assembly chaperones govern biogenesis of the proteasome regulatory particle base.

Q8JZQ0	CSF1_RAT	Macrophage colony-stimulating factor 1	12379742	The osteopetrotic mutation toothless (tl) is a loss-of-function frameshift mutation in the rat Csf1 gene: evidence of a crucial role for CSF-1 in osteoclastogenesis and endochondral ossification.

O74758	YBE3_SCHPO	Uncharacterized protein C17D11.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q62318	TIF1B_MOUSE	Transcription intermediary factor 1-beta	8986806	A novel member of the RING finger family, KRIP-1, associates with the KRAB-A transcriptional repressor domain of zinc finger proteins.

P32597	STH1_YEAST	Nuclear protein STH1/NPS1	8980231	RSC, an essential, abundant chromatin-remodeling complex.

Q9QZ15	CLC4A_MOUSE	C-type lectin domain family 4 member A	10438934	APCs express DCIR, a novel C-type lectin surface receptor containing an immunoreceptor tyrosine-based inhibitory motif.

Q6P1K2	PMF1_HUMAN	Polyamine-modulated factor 1	10419538	Cloning and characterization of human polyamine-modulated factor-1, a transcriptional cofactor that regulates the transcription of the spermidine/spermine N(1)-acetyltransferase gene.

P27801	PEP3_YEAST	Vacuolar membrane protein PEP3	10978279	Pep3p/Pep5p complex: a putative docking factor at multiple steps of vesicular transport to the vacuole of Saccharomyces cerevisiae.

Q75NR7	RECQ4_MOUSE	ATP-dependent DNA helicase Q4	15703196	Defective sister-chromatid cohesion, aneuploidy and cancer predisposition in a mouse model of type II Rothmund-Thomson syndrome.

P38523	GRPE_YEAST	GrpE protein homolog, mitochondrial	8022808	A role for a eukaryotic GrpE-related protein, Mge1p, in protein translocation.

Q01344	IL5RA_HUMAN	Interleukin-5 receptor subunit alpha	1732409	Molecular cloning and expression of the human interleukin 5 receptor.

Q9VFI9	PDE6_DROME	cGMP-specific 3',5'-cyclic phosphodiesterase	18503409	Regulation of a Drosophila melanogaster cGMP-specific phosphodiesterase by prenylation and interaction with a prenyl-binding protein.

Q0WVW7	RQL5_ARATH	ATP-dependent DNA helicase Q-like 5	12856935	Arabidopsis RecQsim, a plant-specific member of the RecQ helicase family, can suppress the MMS hypersensitivity of the yeast sgs1 mutant.

P38193	PP4R2_YEAST	Serine/threonine-protein phosphatase 4 regulatory subunit 2	14562095	Global analysis of protein localization in budding yeast.

Q9UU77	YQMA_SCHPO	Ankyrin repeat-containing protein P1E11.10	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q7TMB8	CYFP1_MOUSE	Cytoplasmic FMR1-interacting protein 1	11438699	A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P.

O42911	RT25_SCHPO	37S ribosomal protein S25, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9P0G3	KLK14_HUMAN	Kallikrein-14	16885167	Proteinase-activated receptors, targets for kallikrein signaling.

Q95ST2	WLS_DROME	Protein wntless	19837038	Trans-synaptic transmission of vesicular Wnt signals through Evi/Wntless.

Q9W252	RAD50_DROME	DNA repair protein RAD50	15135728	Disruption of Drosophila Rad50 causes pupal lethality, the accumulation of DNA double-strand breaks and the induction of apoptosis in third instar larvae.

P22626	ROA2_HUMAN	Heterogeneous nuclear ribonucleoproteins A2/B1	2557628	Primary structures of the heterogeneous nuclear ribonucleoprotein A2, B1, and C2 proteins: a diversity of RNA binding proteins is generated by small peptide inserts.

P42753	CCD31_ARATH	Cyclin-D3-1	11096103	The Arabidopsis D-type cyclins CycD2 and CycD3 both interact in vivo with the PSTAIRE cyclin-dependent kinase Cdc2a but are differentially controlled.

Q9BSI4	TINF2_HUMAN	TERF1-interacting nuclear factor 2	12768206	POT1 as a terminal transducer of TRF1 telomere length control.

P80075	CCL8_HUMAN	C-C motif chemokine 8	9119400	The human MCP-2 gene (SCYA8): cloning, sequence analysis, tissue expression, and assignment to the CC chemokine gene contig on chromosome 17q11.2.

P02489	CRYAA_HUMAN	Alpha-crystallin A chain	18407550	A novel mutation in AlphaA-crystallin (CRYAA) caused autosomal dominant congenital cataract in a large Chinese family.

P33075	KAD1_SCHPO	Adenylate kinase 1	8496185	Molecular analysis of the essential gene for adenylate kinase from the fission yeast Schizosaccharomyces pombe.

Q9UKV3	ACINU_HUMAN	Apoptotic chromatin condensation inducer in the nucleus	10490026	Acinus is a caspase-3-activated protein required for apoptotic chromatin condensation.

P84994	ABP41_LILDA	Villin-like protein ABP41	15557101	Identification and characterization of a Ca2+-dependent actin filament-severing protein from lily pollen.

Q15797	SMAD1_HUMAN	Mothers against decapentaplegic homolog 1	8653785	MADR1, a MAD-related protein that functions in BMP2 signaling pathways.

Q9Z180	SETBP_MOUSE	SET-binding protein	11231286	Identification and characterization of SEB, a novel protein that binds to the acute undifferentiated leukemia-associated protein SET.

P30047	GFRP_HUMAN	GTP cyclohydrolase 1 feedback regulatory protein	16778797	GTP cyclohydrolase feedback regulatory protein controls cofactor 6- tetrahydrobiopterin synthesis in the cytosol and in the nucleus of epidermal keratinocytes and melanocytes.

O95633	FSTL3_HUMAN	Follistatin-related protein 3	11948405	Transcription activation of FLRG and follistatin by activin A, through Smad proteins, participates in a negative feedback loop to modulate activin A function.

P97334	NKX23_MOUSE	Homeobox protein Nkx-2.3	10926756	Homeodomain factor Nkx2-3 controls regional expression of leukocyte homing coreceptor MAdCAM-1 in specialized endothelial cells of the viscera.

O14039	YEY6_SCHPO	Putative methyltransferase C2C4.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P20263	PO5F1_MOUSE	POU domain, class 5, transcription factor 1	19740739	Zfp206, Oct4, and Sox2 are integrated components of a transcriptional regulatory network in embryonic stem cells.

Q3U962	CO5A2_MOUSE	Collagen alpha-2(V) chain	7704020	Targeted mutation in the col5a2 gene reveals a regulatory role for type V collagen during matrix assembly.

Q04739	GAL83_YEAST	SNF1 protein kinase subunit beta-3	12393914	Purification and characterization of Snf1 kinase complexes containing a defined beta subunit composition.

Q9M336	UPP_ARATH	Uracil phosphoribosyltransferase, chloroplastic	19563437	Uracil salvage is necessary for early Arabidopsis development.

Q80X44	ZBT24_MOUSE	Zinc finger and BTB domain-containing protein 24	15526281	Bone morphogenetic protein-2 induces expression of murine zinc finger transcription factor ZNF450.

P32329	YPS1_YEAST	Aspartic proteinase 3	8389368	Purification and characterization of a paired basic residue-specific yeast aspartic protease encoded by the YAP3 gene. Similarity to the mammalian pro-opiomelanocortin-converting enzyme.

P53388	DIP5_YEAST	Dicarboxylic amino acid permease	10654085	Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae.

Q38882	PLDA1_ARATH	Phospholipase D alpha 1	10198096	Subcellular distribution and tissue expression of phospholipase Dalpha, Dbeta, and Dgamma in Arabidopsis.

Q15424	SAFB1_HUMAN	Scaffold attachment factor B1	12660241	SAFB2, a new scaffold attachment factor homolog and estrogen receptor corepressor.

P13264	GLSK_RAT	Glutaminase kidney isoform, mitochondrial	1918000	Isolation, characterization, and in vitro expression of a cDNA that encodes the kidney isoenzyme of the mitochondrial glutaminase.

Q9M6E9	AGGL_ABRPR	Agglutinin-1	16772301	Structure-function analysis and insights into the reduced toxicity of Abrus precatorius agglutinin I in relation to abrin.

Q1JQ73	ELV1A_XENLA	ELAV-like protein 1-A	19458392	Participation of Xenopus Elr-type proteins in vegetal mRNA localization during oogenesis.

Q99829	CPNE1_HUMAN	Copine-1	9430674	The copines, a novel class of C2 domain-containing, calcium- dependent, phospholipid-binding proteins conserved from Paramecium to humans.

P38352	SAF1_YEAST	SCF-associated factor 1	11283612	Skp1 forms multiple protein complexes, including RAVE, a regulator of V-ATPase assembly.

P35729	NU120_YEAST	Nucleoporin NUP120	11823431	Modular self-assembly of a Y-shaped multiprotein complex from seven nucleoporins.

Q9SN27	ATL59_ARATH	E3 ubiquitin-protein ligase ATL59	16339806	Genome analysis and functional characterization of the E2 and RING- type E3 ligase ubiquitination enzymes of Arabidopsis.

Q08230	SDHF2_YEAST	Succinate dehydrogenase assembly factor 2, mitochondrial	19628817	SDH5, a gene required for flavination of succinate dehydrogenase, is mutated in paraganglioma.

P19634	SL9A1_HUMAN	Sodium/hydrogen exchanger 1	2536298	Molecular cloning, primary structure, and expression of the human growth factor-activatable Na+/H+ antiporter.

P93030	RMA2_ARATH	E3 ubiquitin-protein ligase RMA2	19224217	Characterization of three Arabidopsis homologs of human RING membrane anchor E3 ubiquitin ligase.

P46089	GPR3_HUMAN	G-protein coupled receptor 3	7639700	Molecular cloning of an orphan G-protein-coupled receptor that constitutively activates adenylate cyclase.

Q9NRY2	SOSSC_HUMAN	SOSS complex subunit C	19683501	SOSS complexes participate in the maintenance of genomic stability.

P18292	THRB_RAT	Prothrombin	1557383	Partial characterization of vertebrate prothrombin cDNAs: amplification and sequence analysis of the B chain of thrombin from nine different species.

Q9LW29	AFB2_ARATH	Protein AUXIN SIGNALING F-BOX 2	15917797	The F-box protein TIR1 is an auxin receptor.

Q9CZ91	SRFB1_MOUSE	Serum response factor-binding protein 1	15492011	Identification of a novel serum response factor cofactor in cardiac gene regulation.

Q15517	CDSN_HUMAN	Corneodesmosin	9395522	Characterization and purification of human corneodesmosin, an epidermal basic glycoprotein associated with corneocyte-specific modified desmosomes.

Q9SAA2	CLPP6_ARATH	ATP-dependent Clp protease proteolytic subunit 6, chloroplastic	16980539	Structural and functional insights into the chloroplast ATP-dependent Clp protease in Arabidopsis.

Q9TW28	MYOM_DICDI	Myosin-M heavy chain	10828443	Novel Dictyostelium unconventional myosin, MyoM, has a putative RhoGEF domain.

P70270	RAD54_MOUSE	DNA repair and recombination protein RAD54-like	15175260	Rad54 and DNA ligase IV cooperate to maintain mammalian chromatid stability.

O76024	WFS1_HUMAN	Wolframin	16989814	WFS1 protein modulates the free Ca(2+) concentration in the endoplasmic reticulum.

P08579	RU2B_HUMAN	U2 small nuclear ribonucleoprotein B''	2951739	Analysis of a cDNA clone expressing a human autoimmune antigen: full- length sequence of the U2 small nuclear RNA-associated B' antigen.

Q9UKI9	PO2F3_HUMAN	POU domain, class 2, transcription factor 3	10473598	Characterization of the regulatory domains of the human skn-1a/Epoc- 1/Oct-11 POU transcription factor.

Q13111	CAF1A_HUMAN	Chromatin assembly factor 1 subunit A	7600578	The p150 and p60 subunits of chromatin assembly factor I: a molecular link between newly synthesized histones and DNA replication.

Q642F4	SC22A_RAT	Vesicle-trafficking protein SEC22a	8621431	Mammalian vesicle trafficking proteins of the endoplasmic reticulum and Golgi apparatus.

P22987	KIN1_SCHPO	Protein kinase kin1	14596912	The protein kinase kin1, the fission yeast orthologue of mammalian MARK/PAR-1, localises to new cell ends after mitosis and is important for bipolar growth.

O22229	TRXB3_ARATH	NADPH-dependent thioredoxin reductase 3	19470473	NTRC links built-in thioredoxin to light and sucrose in regulating starch synthesis in chloroplasts and amyloplasts.

Q24368	ISWI_DROME	Chromatin-remodeling complex ATPase chain Iswi	16264191	The Drosophila nucleosome remodeling factor NURF is required for Ecdysteroid signaling and metamorphosis.

P42697	DRP1A_ARATH	Dynamin-related protein 1A	15923323	DRP1A is responsible for vascular continuity synergistically working with VAN3 in Arabidopsis.

Q6UPR8	ERMP1_RAT	Endoplasmic reticulum metallopeptidase 1	17267443	Fxna, a novel gene differentially expressed in the rat ovary at the time of folliculogenesis, is required for normal ovarian histogenesis.

P26718	NKG2D_HUMAN	NKG2-D type II integral membrane protein	9683661	The genomic organization of NKG2C, E, F, and D receptor genes in the human natural killer gene complex.

P54003	SUR7_YEAST	Protein SUR7	12469340	Subproteomics: identification of plasma membrane proteins from the yeast Saccharomyces cerevisiae.

Q13617	CUL2_HUMAN	Cullin-2	17304241	The Caenorhabditis elegans cell-cycle regulator ZYG-11 defines a conserved family of CUL-2 complex components.

Q61080	FOXF1_MOUSE	Forkhead box protein F1	7958446	Members of the HNF-3/forkhead family of transcription factors exhibit distinct cellular expression patterns in lung and regulate the surfactant protein B promoter.

P34470	HCP3_CAEEL	Histone H3-like centromeric protein hcp-3	10524621	A histone-H3-like protein in C. elegans.

P62166	NCS1_HUMAN	Neuronal calcium sensor 1	12783849	IL1 receptor accessory protein like, a protein involved in X-linked mental retardation, interacts with Neuronal Calcium Sensor-1 and regulates exocytosis.

Q9R190	MTA2_MOUSE	Metastasis-associated protein MTA2	10444591	Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation.

Q92854	SEM4D_HUMAN	Semaphorin-4D	8876214	Human CD100, a novel leukocyte semaphorin that promotes B-cell aggregation and differentiation.

Q9UNA1	RHG26_HUMAN	Rho GTPase-activating protein 26	10908648	The human GRAF gene is fused to MLL in a unique t(5;11)(q31;q23) and both alleles are disrupted in three cases of myelodysplastic syndrome/acute myeloid leukemia with a deletion 5q.

P36118	NTR2_YEAST	Pre-mRNA-splicing factor NTR2	16880513	Yeast ntr1/spp382 mediates prp43 function in postspliceosomes.

P83941	ELOC_RAT	Transcription elongation factor B polypeptide 1	10213691	Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase.

O43187	IRAK2_HUMAN	Interleukin-1 receptor-associated kinase-like 2	10383454	IRAK-M is a novel member of the Pelle/interleukin-1 receptor- associated kinase (IRAK) family.

Q8BUN5	SMAD3_MOUSE	Mothers against decapentaplegic homolog 3	18039968	Ttrap is an essential modulator of Smad3-dependent Nodal signaling during zebrafish gastrulation and left-right axis determination.

Q99683	M3K5_HUMAN	Mitogen-activated protein kinase kinase kinase 5	17210579	Apoptosis signal-regulating kinase (ASK) 2 functions as a mitogen- activated protein kinase kinase kinase in a heteromeric complex with ASK1.

O54916	REPS1_MOUSE	RalBP1-associated Eps domain-containing protein 1	9395447	An eps homology (EH) domain protein that binds to the ral-GTPase target, RalBP1.

Q92974	ARHG2_HUMAN	Rho guanine nucleotide exchange factor 2	19043560	GEF-H1 mediated control of NOD1 dependent NF-kappaB activation by Shigella effectors.

Q99N14	TKN4_MOUSE	Tachykinin-4	11062498	Hemokinin is a hematopoietic-specific tachykinin that regulates B lymphopoiesis.

P38753	HSE1_YEAST	Class E vacuolar protein-sorting machinery protein HSE1	12055639	The Vps27p-Hse1p complex binds ubiquitin and mediates endosomal protein sorting.

Q7KHG2	JING_DROME	Zinc finger protein jing	12015288	The jing Zn-finger transcription factor is a mediator of cellular differentiation in the Drosophila CNS midline and trachea.

Q9UKV8	AGO2_HUMAN	Protein argonaute-2	18771919	Importance of translation and nonnucleolytic ago proteins for on- target RNA interference.

Q9BXW9	FACD2_HUMAN	Fanconi anemia group D2 protein	17460694	FANCI is a second monoubiquitinated member of the Fanconi anemia pathway.

P89886	TMA20_YEAST	Translation machinery-associated protein 20	14562095	Global analysis of protein localization in budding yeast.

P14891	HMDH1_ARATH	3-hydroxy-3-methylglutaryl-coenzyme A reductase 1	2649893	3-hydroxy-3-methylglutaryl-coenzyme A reductase from Arabidopsis thaliana is structurally distinct from the yeast and animal enzymes.

P82874	TO203_ARATH	Mitochondrial import receptor subunit TOM20-3	16461275	Convergent evolution of receptors for protein import into mitochondria.

P43686	PRS6B_HUMAN	26S protease regulatory subunit 6B	8603043	A component of the 26S proteasome binds on orphan member of the nuclear hormone receptor superfamily.

Q08491	SKI7_YEAST	Superkiller protein 7	16043509	Domain interactions within the Ski2/3/8 complex and between the Ski complex and Ski7p.

P09880	TRNL_YEAST	tRNA ligase	2207062	Domain structure in yeast tRNA ligase.

P01782	HV321_HUMAN	Ig heavy chain V-III region DOB	114209	Amino acid sequence of the heavy-chain variable region of the crystallizable human myeloma protein Dob.

Q9Y6Y9	LY96_HUMAN	Lymphocyte antigen 96	10359581	MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4.

Q9US11	YK67_SCHPO	Uncharacterized protein C607.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Y7U4	NSE3_SCHPO	Non-structural maintenance of chromosome element 3	16478984	The Nse5-Nse6 dimer mediates DNA repair roles of the Smc5-Smc6 complex.

Q14596	NBR1_HUMAN	Next to BRCA1 gene 1 protein	19250911	A role for NBR1 in autophagosomal degradation of ubiquitinated substrates.

P34348	RFS1_CAEEL	RAD51-like protein 1	11778048	Combined functional genomic maps of the C. elegans DNA damage response.

Q3E7B6	VA0E_YEAST	V-type proton ATPase subunit e	14970230	The yeast vacuolar proton-translocating ATPase contains a subunit homologous to the Manduca sexta and bovine e subunits that is essential for function.

Q1JPY4	TBPL2_DANRE	TATA box-binding protein-like protein 2	15062100	TBP2, a vertebrate-specific member of the TBP family, is required in embryonic development of zebrafish.

Q86YP4	P66A_HUMAN	Transcriptional repressor p66-alpha	12183469	Two highly related p66 proteins comprise a new family of potent transcriptional repressors interacting with MBD2 and MBD3.

Q16651	PRSS8_HUMAN	Prostasin	8034638	Prostasin is a novel human serine proteinase from seminal fluid. Purification, tissue distribution, and localization in prostate gland.

Q80ZG1	RIC8A_RAT	Synembryn-A	12509430	Mammalian Ric-8A (synembryn) is a heterotrimeric Galpha protein guanine nucleotide exchange factor.

P50443	S26A2_HUMAN	Sulfate transporter	7923357	The diastrophic dysplasia gene encodes a novel sulfate transporter: positional cloning by fine-structure linkage disequilibrium mapping.

O43603	GALR2_HUMAN	Galanin receptor type 2	9832121	Molecular characterization and expression of cloned human galanin receptors GALR2 and GALR3.

Q9D8M7	PHF10_MOUSE	PHD finger protein 10	17640523	An essential switch in subunit composition of a chromatin remodeling complex during neural development.

P0AA37	RLUA_ECOLI	Ribosomal large subunit pseudouridine synthase A	10383384	Functional effect of deletion and mutation of the Escherichia coli ribosomal RNA and tRNA pseudouridine synthase RluA.

Q06967	14336_ORYSJ	14-3-3-like protein GF14-F	8405471	Molecular structure of ras-related small GTP-binding protein genes of rice plants and GTPase activities of gene products in Escherichia coli.

P02652	APOA2_HUMAN	Apolipoprotein A-II	11991719	Cloning and characterization of a novel apolipoprotein A-I-binding protein, AI-BP, secreted by cells of the kidney proximal tubules in response to HDL or ApoA-I.

O95125	ZN202_HUMAN	Zinc finger protein 202	9790754	Molecular cloning and characterization of ZNF202: a new gene at 11q23.3 encoding testis-specific zinc finger proteins.

Q8R431	MGLL_RAT	Monoglyceride lipase	12136125	Brain monoglyceride lipase participating in endocannabinoid inactivation.

O02350	CBPA1_ANOGA	Zinc carboxypeptidase A 1	9569647	Rapid induction by a blood meal of a carboxypeptidase gene in the gut of the mosquito Anopheles gambiae.

O95782	AP2A1_HUMAN	AP-2 complex subunit alpha-1	12036598	Cloning, physical mapping and structural characterization of the human alpha(A)-adaptin gene.

P60752	MSBA_ECOLI	Lipid A export ATP-binding/permease protein msbA	8809774	Mutational analysis and properties of the msbA gene of Escherichia coli, coding for an essential ABC family transporter.

Q9UHB4	NDOR1_HUMAN	NADPH-dependent diflavin oxidoreductase 1	10625700	Cloning and characterization of a novel human dual flavin reductase.

P15204	THAA_XENLA	Thyroid hormone receptor alpha-A	8969201	Functional characterization of a mutant thyroid hormone receptor in Xenopus laevis.

P40348	RFC2_YEAST	Replication factor C subunit 2	12604797	Yeast Rad17/Mec3/Ddc1: a sliding clamp for the DNA damage checkpoint.

Q99527	GPER_HUMAN	G-protein coupled estrogen receptor 1	8920907	Cloning of human cDNA encoding a novel heptahelix receptor expressed in Burkitt's lymphoma and widely distributed in brain and peripheral tissues.

Q9NDC9	LIS1_CAEEL	Lissencephaly-1 homolog	11685578	Evolutionarily conserved nuclear migration genes required for early embryonic development in Caenorhabditis elegans.

Q9Y709	SKP1_SCHPO	Suppressor of kinetochore protein 1	12167173	Combinatorial diversity of fission yeast SCF ubiquitin ligases by homo- and heterooligomeric assemblies of the F-box proteins Pop1p and Pop2p.

Q93149	ACR3_CAEEL	Acetylcholine receptor subunit beta-type acr-3	9606719	ACR-3, a Caenorhabditis elegans nicotinic acetylcholine receptor subunit. Molecular cloning and functional expression.

P0C1T0	MMEL1_RAT	Membrane metallo-endopeptidase-like 1	15294904	A three-dimensional model of the neprilysin 2 active site based on the X-ray structure of neprilysin. Identification of residues involved in substrate hydrolysis and inhibitor binding of neprilysin 2.

Q9Z2N8	ACL6A_MOUSE	Actin-like protein 6A	17640523	An essential switch in subunit composition of a chromatin remodeling complex during neural development.

P32305	5HT7R_RAT	5-hydroxytryptamine receptor 7	8397408	Molecular cloning, characterization, and localization of a high- affinity serotonin receptor (5-HT7) activating cAMP formation.

Q9FZ96	PUP1_ARATH	Purine permease 1	12662305	Transport of cytokinins mediated by purine transporters of the PUP family expressed in phloem, hydathodes, and pollen of Arabidopsis.

Q6E434	TRF1_SCHPO	Telomeric DNA-binding factor trf1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9HD43	PTPRH_HUMAN	Receptor-type tyrosine-protein phosphatase H	8294459	Molecular cloning of a human transmembrane-type protein tyrosine phosphatase and its expression in gastrointestinal cancers.

P87175	APN2_SCHPO	DNA-(apurinic or apyrimidinic site) lyase 2	14599746	Fission yeast Uve1 and Apn2 function in distinct oxidative damage repair pathways in vivo.

Q62318	TIF1B_MOUSE	Transcription intermediary factor 1-beta	10562550	Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family.

P00568	KAD1_HUMAN	Adenylate kinase isoenzyme 1	2542324	Human adenylate kinase deficiency associated with hemolytic anemia. A single base substitution affecting solubility and catalytic activity of the cytosolic adenylate kinase.

P70512	HNF6_RAT	Hepatocyte nuclear factor 6	9593691	Isoforms of hepatocyte nuclear factor-6 differ in DNA-binding properties, contain a bifunctional homeodomain, and define the new ONECUT class of homeodomain proteins.

P60896	DSS1_HUMAN	26S proteasome complex subunit DSS1	12228710	BRCA2 function in DNA binding and recombination from a BRCA2-DSS1- ssDNA structure.

Q8TDX6	CGAT1_HUMAN	Chondroitin sulfate N-acetylgalactosaminyltransferase 1	12163485	Enzymatic synthesis of chondroitin with a novel chondroitin sulfate N-acetylgalactosaminyltransferase that transfers N-acetylgalactosamine to glucuronic acid in initiation and elongation of chondroitin sulfate synthesis.

Q9BQL6	FERM1_HUMAN	Fermitin family homolog 1	17012746	Kindlin-1 is a phosphoprotein involved in regulation of polarity, proliferation, and motility of epidermal keratinocytes.

O74476	IMB3_SCHPO	Importin subunit beta-3	12399381	The sal3(+) gene encodes an importin-beta implicated in the nuclear import of cdc25 in Schizosaccharomyces pombe.

Q8AV13	ANM1A_XENLA	Protein arginine N-methyltransferase 1-A	12466543	Methylation of Xenopus CIRP2 regulates its arginine- and glycine-rich region-mediated nucleocytoplasmic distribution.

Q92945	FUBP2_HUMAN	Far upstream element-binding protein 2	9136930	A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer.

Q9QY10	FGFP1_RAT	Fibroblast growth factor-binding protein 1	10831072	Tissue distribution and retinoid-mediated downregulation of an FGF- binding protein (FGF-BP) in the rat.

Q9D030	TWST2_MOUSE	Twist-related protein 2	7589808	Dermo-1: a novel twist-related bHLH protein expressed in the developing dermis.

Q6IMG9	TEPP_RAT	Testis, prostate and placenta-expressed protein	14652002	TEPP, a new gene specifically expressed in testis, prostate, and placenta and well conserved in chordates.

P32456	GBP2_HUMAN	Interferon-induced guanylate-binding protein 2	1715024	Interferon-induced guanylate-binding proteins lack an N(T)KXD consensus motif and bind GMP in addition to GDP and GTP.

Q9JKB3	DBPA_MOUSE	DNA-binding protein A	12117816	Translational repression by MSY4 inhibits spermatid differentiation in mice.

O15503	INSI1_HUMAN	Insulin-induced gene 1 protein	9268630	Cloning, human chromosomal assignment, and adipose and hepatic expression of the CL-6/INSIG1 gene.

P51433	PA2G5_RAT	Calcium-dependent phospholipase A2	7947992	Cloning, expression and partial characterization of a novel rat phospholipase A2.

Q9M2J7	LBD29_ARATH	LOB domain-containing protein 29	17259263	ARF7 and ARF19 regulate lateral root formation via direct activation of LBD/ASL genes in Arabidopsis.

Q9QY15	DDX25_MOUSE	ATP-dependent RNA helicase DDX25	10608860	A novel gonadotropin-regulated testicular RNA helicase: a new member of the DEAD-box family.

Q9U9Y8	NLK_CAEEL	Serine/threonine kinase NLK	9384382	Binary specification of the embryonic lineage in Caenorhabditis elegans.

P52298	NCBP2_HUMAN	Nuclear cap-binding protein subunit 2	17873884	Failsafe nonsense-mediated mRNA decay does not detectably target eIF4E-bound mRNA.

P80299	HYES_RAT	Epoxide hydrolase 2	12574508	The N-terminal domain of mammalian soluble epoxide hydrolase is a phosphatase.

P32350	KNS1_YEAST	Dual specificity protein kinase KNS1	8910305	Activity and autophosphorylation of LAMMER protein kinases.

Q8VIL3	ZWINT_RAT	ZW10 interactor	12068081	Identification of a novel SNAP25 interacting protein (SIP30).

O00213	APBB1_HUMAN	Amyloid beta A4 precursor protein-binding family B member 1	19234442	Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions.

O36027	WSP1_SCHPO	Wiskott-Aldrich syndrome protein homolog 1	12939254	The PCH family protein, Cdc15p, recruits two F-actin nucleation pathways to coordinate cytokinetic actin ring formation in Schizosaccharomyces pombe.

P38324	SLX1_YEAST	Structure-specific endonuclease subunit SLX1	11139495	Requirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiae.

O74923	YJ7D_SCHPO	Uncharacterized transporter C757.13	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P05755	RS9B_YEAST	40S ribosomal protein S9-B	15590835	The small-subunit processome is a ribosome assembly intermediate.

Q9W769	VEX1_XENLA	Homeobox protein vex1	10585564	The Xvex-1 antimorph reveals the temporal competence for organizer formation and an early role for ventral homeobox genes.

Q91V14	S12A5_MOUSE	Solute carrier family 12 member 5	11395011	Disruption of KCC2 reveals an essential role of K-Cl cotransport already in early synaptic inhibition.

Q08193	GAS5_YEAST	1,3-beta-glucanosyltransferase GAS5	17397106	The Gas family of proteins of Saccharomyces cerevisiae: characterization and evolutionary analysis.

P00995	ISK1_HUMAN	Pancreatic secretory trypsin inhibitor	7142173	Purification and characterization of a tumor-associated trypsin inhibitor from the urine of a patient with ovarian cancer.

P56558	OGT1_RAT	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit	9083067	Dynamic glycosylation of nuclear and cytosolic proteins. Cloning and characterization of a unique O-GlcNAc transferase with multiple tetratricopeptide repeats.

Q9UBK2	PRGC1_HUMAN	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha	10713165	A tissue-specific coactivator of steroid receptors, identified in a functional genetic screen.

Q14956	GPNMB_HUMAN	Transmembrane glycoprotein NMB	7814155	NMB, a novel gene, is expressed in low-metastatic human melanoma cell lines and xenografts.

Q9Y803	YN98_SCHPO	S1-like domain-containing protein C146.08c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O75312	ZPR1_HUMAN	Zinc finger protein ZPR1	9763455	The cytoplasmic zinc finger protein ZPR1 accumulates in the nucleolus of proliferating cells.

Q9Y2V2	CHSP1_HUMAN	Calcium-regulated heat stable protein 1	9712905	Purification and characterization of a novel physiological substrate for calcineurin in mammalian cells.

Q86TM6	SYVN1_HUMAN	E3 ubiquitin-protein ligase synoviolin	18502753	Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiP.

P14902	I23O1_HUMAN	Indoleamine 2,3-dioxygenase 1	2109605	Molecular cloning, sequencing and expression of human interferon- gamma-inducible indoleamine 2,3-dioxygenase cDNA.

P52566	GDIR2_HUMAN	Rho GDP-dissociation inhibitor 2	8434008	cDNA cloning of a human mRNA preferentially expressed in hematopoietic cells and with homology to a GDP-dissociation inhibitor for the rho GTP-binding proteins.

P38251	RFC5_YEAST	Replication factor C subunit 5	7651383	Characterization of the five replication factor C genes of Saccharomyces cerevisiae.

P49282	NRAM2_MOUSE	Natural resistance-associated macrophage protein 2	11739192	Characterization of the iron transporter DMT1 (NRAMP2/DCT1) in red blood cells of normal and anemic mk/mk mice.

P43341	LPXH_ECOLI	UDP-2,3-diacylglucosamine hydrolase	12000771	Accumulation of the lipid A precursor UDP-2,3-diacylglucosamine in an Escherichia coli mutant lacking the lpxH gene.

O13844	YFG5_SCHPO	Uncharacterized mitochondrial carrier C19G12.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O24409	IAA19_ARATH	Auxin-responsive protein IAA19	14729917	MASSUGU2 encodes Aux/IAA19, an auxin-regulated protein that functions together with the transcriptional activator NPH4/ARF7 to regulate differential growth responses of hypocotyl and formation of lateral roots in Arabidopsis thaliana.

Q12024	YTM1_YEAST	Ribosome biogenesis protein YTM1	18448671	Interactions among Ytm1, Erb1, and Nop7 required for assembly of the Nop7-subcomplex in yeast preribosomes.

P40505	SDS3_YEAST	Transcriptional regulatory protein SDS3	11024051	Sds3 (suppressor of defective silencing 3) is an integral component of the yeast Sin3[middle dot]Rpd3 histone deacetylase complex and is required for histone deacetylase activity.

P32828	SLX5_YEAST	E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5	17848550	The yeast Hex3.Slx8 heterodimer is a ubiquitin ligase stimulated by substrate sumoylation.

P35658	NU214_HUMAN	Nuclear pore complex protein Nup214	8108440	The human CAN protein, a putative oncogene product associated with myeloid leukemogenesis, is a nuclear pore complex protein that faces the cytoplasm.

Q5ZRQ0	LUBX_LEGPH	E3 ubiquitin-protein ligase LubX	18284575	Legionella translocates an E3 ubiquitin ligase that has multiple U- boxes with distinct functions.

P30532	ACHA5_HUMAN	Neuronal acetylcholine receptor subunit alpha-5	9009220	Cloning and sequence of full-length cDNAs encoding the human neuronal nicotinic acetylcholine receptor (nAChR) subunits beta3 and beta4 and expression of seven nAChR subunits in the human neuroblastoma cell line SH-SY5Y and/or IMR-32.

P49735	MCM2_DROME	DNA replication licensing factor Mcm2	12808023	Drosophila MCM10 interacts with members of the prereplication complex and is required for proper chromosome condensation.

Q9JMF3	GBG13_MOUSE	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13	10679242	Growth suppression of Escherichia coli by induction of expression of mammalian genes with transmembrane or ATPase domains.

O14818	PSA7_HUMAN	Proteasome subunit alpha type-7	16251969	A heterodimeric complex that promotes the assembly of mammalian 20S proteasomes.

Q8MN58	CLC_DICDI	Clathrin light chain	9425628	Purification of clathrin heavy and light chain from Dictyostelium discoideum.

O36023	SPN1_SCHPO	Septin homolog spn1	15385632	Requirements of fission yeast septins for complex formation, localization, and function.

Q99424	ACOX2_HUMAN	Peroxisomal acyl-coenzyme A oxidase 2	8943006	Molecular characterization of the human peroxisomal branched-chain acyl-CoA oxidase: cDNA cloning, chromosomal assignment, tissue distribution, and evidence for the absence of the protein in Zellweger's syndrome.

Q92536	YLAT2_HUMAN	Y+L amino acid transporter 2	9829974	Identification and characterization of a membrane protein (y+L amino acid transporter-1) that associates with 4F2hc to encode the amino acid transport activity y+L. A candidate gene for lysinuric protein intolerance.

O94502	YBT5_SCHPO	Uncharacterized mitochondrial carrier C12D12.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P54860	UFD2_YEAST	E4 ubiquitin-protein ligase UFD2	14562095	Global analysis of protein localization in budding yeast.

Q39030	KPK2_ARATH	Serine/threonine-protein kinase AtPK2/AtPK19	7828736	Two genes that encode ribosomal-protein S6 kinase homologs are induced by cold or salinity stress in Arabidopsis thaliana.

O60832	DKC1_HUMAN	H/ACA ribonucleoprotein complex subunit 4	10591218	A telomerase component is defective in the human disease dyskeratosis congenita.

Q54T81	DKC1_DICDI	Probable H/ACA ribonucleoprotein complex subunit 4	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

P43638	MHP1_YEAST	MAP-homologous protein 1	8947554	MHP1, an essential gene in Saccharomyces cerevisiae required for microtubule function.

P18615	NELFE_HUMAN	Negative elongation factor E	2119325	The human RD protein is closely related to nuclear RNA-binding proteins and has been highly conserved.

A7UNK4	AGBL_LYODE	Alpha-galactosyl-binding lectin	17904093	A new alpha-galactosyl-binding protein from the mushroom Lyophyllum decastes.

Q06214	JIP5_YEAST	WD repeat-containing protein JIP5	14690591	Assigning function to yeast proteins by integration of technologies.

Q61955	KLK8_MOUSE	Kallikrein-8	11274744	Expression of neuropsin in oligodendrocytes after injury to the CNS.

Q9JLA3	UGGG1_RAT	UDP-glucose:glycoprotein glucosyltransferase 1	10764828	Cloning and characterization of mammalian UDP-glucose glycoprotein:glucosyltransferase and the development of a specific substrate for this enzyme.

P51956	NEK3_HUMAN	Serine/threonine-protein kinase Nek3	7522034	Cell cycle-dependent expression of Nek2, a novel human protein kinase related to the NIMA mitotic regulator of Aspergillus nidulans.

Q9W6H5	UBC9A_DANRE	SUMO-conjugating enzyme UBC9-A	17035631	Ubc9 regulates mitosis and cell survival during Zebrafish development.

P20142	PEPC_HUMAN	Gastricsin	3335549	Primary structure of human pepsinogen C gene.

P63072	UBD_MOUSE	Ubiquitin D	16782901	FAT10/diubiquitin-like protein-deficient mice exhibit minimal phenotypic differences.

Q9Y6D9	MD1L1_HUMAN	Mitotic spindle assembly checkpoint protein MAD1	18981471	Tpr directly binds to Mad1 and Mad2 and is important for the Mad1- Mad2-mediated mitotic spindle checkpoint.

P40004	YEA4_YEAST	UDP-N-acetylglucosamine transporter YEA4	10788474	Characterization of Yeast Yea4p, a uridine diphosphate-N- acetylglucosamine transporter localized in the endoplasmic reticulum and required for chitin synthesis.

Q02080	MEF2B_HUMAN	Myocyte-specific enhancer factor 2B	15567413	Mechanism of recruitment of class II histone deacetylases by myocyte enhancer factor-2.

Q9ZPS9	BRL2_ARATH	Serine/threonine-protein kinase BRI1-like 2	12417696	VH1, a provascular cell-specific receptor kinase that influences leaf cell patterns in Arabidopsis.

P0AES2	GUDH_ECOLI	Glucarate dehydratase	9772162	Evolution of enzymatic activities in the enolase superfamily: characterization of the (D)-glucarate/galactarate catabolic pathway in Escherichia coli.

P06104	UBC2_YEAST	Ubiquitin-conjugating enzyme E2 2	9287349	Yeast DNA repair proteins Rad6 and Rad18 form a heterodimer that has ubiquitin conjugating, DNA binding, and ATP hydrolytic activities.

P10275	ANDR_HUMAN	Androgen receptor	18451177	TRIM68 regulates ligand-dependent transcription of androgen receptor in prostate cancer cells.

Q93009	UBP7_HUMAN	Ubiquitin carboxyl-terminal hydrolase 7	12093161	USP7, a ubiquitin-specific protease, interacts with ataxin-1, the SCA1 gene product.

P10989	ACT_SCHPO	Actin	8774852	An actin point-mutation neighboring the 'hydrophobic plug' causes defects in the maintenance of cell polarity and septum organization in the fission yeast Schizosaccharomyces pombe.

Q6XAT2	ERL2_ARATH	LRR receptor-like serine/threonine-protein kinase ERL2	17652352	Haploinsufficiency after successive loss of signaling reveals a role for ERECTA-family genes in Arabidopsis ovule development.

O74843	SIF1_SCHPO	Sad1-interacting factor 1	14655046	Two-hybrid search for proteins that interact with Sad1 and Kms1, two membrane-bound components of the spindle pole body in fission yeast.

O75822	EIF3J_HUMAN	Eukaryotic translation initiation factor 3 subunit J	18599441	Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3.

Q6DGF8	TMM18_RAT	Transmembrane protein 18	18559506	Transmembrane protein 18 enhances the tropism of neural stem cells for glioma cells.

P52742	ZN135_HUMAN	Zinc finger protein 135	7557990	Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders.

P53950	VAC7_YEAST	Vacuolar segregation protein 7	11950935	Regulation of Fab1 phosphatidylinositol 3-phosphate 5-kinase pathway by Vac7 protein and Fig4, a polyphosphoinositide phosphatase family member.

Q52LW3	RHG29_HUMAN	Rho GTPase-activating protein 29	9305890	A novel GTPase-activating protein for Rho interacts with a PDZ domain of the protein-tyrosine phosphatase PTPL1.

P14778	IL1R1_HUMAN	Interleukin-1 receptor type 1	2530587	Cloning the interleukin 1 receptor from human T cells.

O94400	YQF7_SCHPO	PHD and RING finger domain-containing protein C126.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q03497	STE20_YEAST	Serine/threonine-protein kinase STE20	10970855	Yeast Cdc42 GTPase and Ste20 PAK-like kinase regulate Sho1-dependent activation of the Hog1 MAPK pathway.

Q9SU14	NUDT7_ARATH	Nudix hydrolase 7	15878881	Comprehensive analysis of cytosolic nudix hydrolases in Arabidopsis thaliana.

O95715	CXL14_HUMAN	C-X-C motif chemokine 14	10049774	Cloning of BRAK, a novel divergent CXC chemokine preferentially expressed in normal versus malignant cells.

Q9Y801	YFAS1_SCHPO	FAS1 domain-containing protein mug57	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P38825	TOM71_YEAST	Protein TOM71	16407407	Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins.

Q9Y5T5	UBP16_HUMAN	Ubiquitin carboxyl-terminal hydrolase 16	17512543	Solution structure of the Ubp-M BUZ domain, a highly specific protein module that recognizes the C-terminal tail of free ubiquitin.

P51798	CLCN7_HUMAN	H(+)/Cl(-) exchange transporter 7	8543009	ClC-6 and ClC-7 are two novel broadly expressed members of the CLC chloride channel family.

P08621	RU17_HUMAN	U1 small nuclear ribonucleoprotein 70 kDa	9531537	A coactivator of pre-mRNA splicing.

Q9Y662	HS3SB_HUMAN	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1	9988768	Expression of heparan sulfate D-glucosaminyl 3-O-sulfotransferase isoforms reveals novel substrate specificities.

P20486	CKS1_YEAST	Cyclin-dependent kinases regulatory subunit	2664468	The Saccharomyces cerevisiae CKS1 gene, a homolog of the Schizosaccharomyces pombe suc1+ gene, encodes a subunit of the Cdc28 protein kinase complex.

Q8NCD3	HJURP_HUMAN	Holliday junction recognition protein	19410545	HJURP is a cell-cycle-dependent maintenance and deposition factor of CENP-A at centromeres.

Q99N37	RHG17_RAT	Rho GTPase-activating protein 17	10967100	Nadrin, a novel neuron-specific GTPase-activating protein involved in regulated exocytosis.

P17532	TPH1_MOUSE	Tryptophan 5-hydroxylase 1	2110547	Characterization and chromosomal mapping of a cDNA encoding tryptophan hydroxylase from a mouse mastocytoma cell line.

P48813	GNP1_YEAST	High-affinity glutamine permease	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

C0LGG8	Y5343_ARATH	Probable LRR receptor-like serine/threonine-protein kinase At1g53430	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P32785	FMT_YEAST	Methionyl-tRNA formyltransferase, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q5VZM2	RRAGB_HUMAN	Ras-related GTP-binding protein B	9394008	RagA is a functional homologue of S. cerevisiae Gtr1p involved in the Ran/Gsp1-GTPase pathway.

Q10711	ECE2_BOVIN	Endothelin-converting enzyme 2	7797512	Endothelin-converting enzyme-2 is a membrane-bound, phosphoramidon- sensitive metalloprotease with acidic pH optimum.

Q6DUW6	IDL4_ARATH	Protein IDA-LIKE 4	18660431	The EPIP peptide of INFLORESCENCE DEFICIENT IN ABSCISSION is sufficient to induce abscission in arabidopsis through the receptor- like kinases HAESA and HAESA-LIKE2.

O59790	ARK1_SCHPO	Serine/threonine-protein kinase ark1	16199877	Suppressors of Bir1p (Survivin) identify roles for the chromosomal passenger protein Pic1p (INCENP) and the replication initiation factor Psf2p in chromosome segregation.

P32578	SIP1_YEAST	SNF1 protein kinase subunit beta-1	11331606	Subcellular localization of the Snf1 kinase is regulated by specific beta subunits and a novel glucose signaling mechanism.

Q8N138	ORML3_HUMAN	ORM1-like protein 3	20182505	Orm family proteins mediate sphingolipid homeostasis.

P03905	NU4M_HUMAN	NADH-ubiquinone oxidoreductase chain 4	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

Q9ERC8	DSCAM_MOUSE	Down syndrome cell adhesion molecule homolog	19196994	DSCAM functions as a netrin receptor in commissural axon pathfinding.

Q64689	SIA8C_MOUSE	Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase	7782326	Molecular cloning of Sia alpha 2,3Gal beta 1,4GlcNAc alpha 2,8- sialyltransferase from mouse brain.

Q62928	PE2R2_RAT	Prostaglandin E2 receptor EP2 subtype	9440134	Molecular cloning and expression of a rat prostaglandin E2 receptor of the EP2 subtype.

Q7TMB7	LPPR4_RAT	Lipid phosphate phosphatase-related protein type 4	12730698	A new phospholipid phosphatase, PRG-1, is involved in axon growth and regenerative sprouting.

P83581	HS74L_RAT	Heat shock 70 kDa protein 4L	12423363	Characterization of the 105-kDa molecular chaperone. Identification, biochemical properties, and localization.

Q9NP85	PODO_HUMAN	Podocin	10742096	NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome.

Q39193	SRK2I_ARATH	Serine/threonine-protein kinase SRK2I	15292193	Identification of nine sucrose nonfermenting 1-related protein kinases 2 activated by hyperosmotic and saline stresses in Arabidopsis thaliana.

P18598	ATP4B_RAT	Potassium-transporting ATPase subunit beta	2165052	cDNA cloning of the beta-subunit of the rat gastric H,K-ATPase.

Q9N2M8	HDC_DROME	Headcase protein	9531534	Translational readthrough in the hdc mRNA generates a novel branching inhibitor in the Drosophila trachea.

Q8IWL2	SFTA1_HUMAN	Pulmonary surfactant-associated protein A1	2995821	Isolation and characterization of the human pulmonary surfactant apoprotein gene.

Q9H9T3	ELP3_HUMAN	Elongator complex protein 3	11818576	Human Elongator facilitates RNA polymerase II transcription through chromatin.

Q9BQ08	RETNB_HUMAN	Resistin-like beta	11209052	A family of tissue-specific resistin-like molecules.

Q61382	TRAF4_MOUSE	TNF receptor-associated factor 4	10934170	TRAF4 deficiency leads to tracheal malformation with resulting alterations in air flow to the lungs.

P0A825	GLYA_ECOLI	Serine hydroxymethyltransferase	6190704	Characterization of the Escherichia coli gene for serine hydroxymethyltransferase.

O94317	YH5D_SCHPO	Uncharacterized serine-rich protein C215.13	12845604	Genome-wide identification of fungal GPI proteins.

O94952	FBX21_HUMAN	F-box only protein 21	10531035	Identification of a family of human F-box proteins.

P25853	BAM5_ARATH	Beta-amylase 5	7716246	Sugar-inducible expression of a gene for beta-amylase in Arabidopsis thaliana.

P50115	S10A8_RAT	Protein S100-A8	8343166	Expression and cloning of migration inhibitory factor-related protein (MRP)8 and MRP14 in arthritis-susceptible rats.

P38883	RIX1_YEAST	Pre-rRNA-processing protein RIX1	14759368	High-definition macromolecular composition of yeast RNA-processing complexes.

Q9M276	ATB12_ARATH	Homeobox-leucine zipper protein ATHB-12	9617808	A new homeodomain-leucine zipper gene from Arabidopsis thaliana induced by water stress and abscisic acid treatment.

O88502	PDE8A_MOUSE	High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	9671792	Cloning and characterization of a cAMP-specific cyclic nucleotide phosphodiesterase.

P25618	CWH43_YEAST	Protein CWH43	17761529	Saccharomyces cerevisiae CWH43 is involved in the remodeling of the lipid moiety of GPI anchors to ceramides.

P39406	RSMC_ECOLI	Ribosomal RNA small subunit methyltransferase C	17576679	Functional specialization of domains tandemly duplicated within 16S rRNA methyltransferase RsmC.

P50749	RASF2_HUMAN	Ras association domain-containing protein 2	12732644	RASSF2 is a novel K-Ras-specific effector and potential tumor suppressor.

P39719	FLC2_YEAST	Flavin carrier protein 2	16717099	A screen for genes of heme uptake identifies the FLC family required for import of FAD into the endoplasmic reticulum.

Q9ZNR6	PDX12_ARATH	Probable pyridoxal biosynthesis protein PDX1.2	16766694	Analysis of the Arabidopsis rsr4-1/pdx1-3 mutant reveals the critical function of the PDX1 protein family in metabolism, development, and vitamin B6 biosynthesis.

P36001	FOLC_YEAST	Probable folylpolyglutamate synthase	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q03761	TAF12_YEAST	Transcription initiation factor TFIID subunit 12	9674426	A subset of TAF(II)s are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulation.

Q8CIG3	KDM1B_MOUSE	Lysine-specific histone demethylase 1B	19727073	KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints.

Q9QZ29	IGB1B_MOUSE	Immunoglobulin-binding protein 1b	10491115	A new member of the alpha4-related molecule (alpha4-b) that binds to the protein phosphatase 2A is expressed selectively in the brain and testis.

Q9FH76	ABAH3_ARATH	Abscisic acid 8'-hydroxylase 3	15064374	Arabidopsis CYP707As encode (+)-abscisic acid 8'-hydroxylase, a key enzyme in the oxidative catabolism of abscisic acid.

Q9VFK3	SOTI_DROME	Male-specific protein scotti	18434411	Post-meiotic transcription in Drosophila testes.

P46100	ATRX_HUMAN	Transcriptional regulator ATRX	7697714	Mutations in a putative global transcriptional regulator cause X- linked mental retardation with alpha-thalassemia (ATR-X syndrome).

Q9W7E8	KOZA_XENLA	Homeobox protein koza	12454933	Xenopus bagpipe-related gene, koza, may play a role in regulation of cell proliferation.

Q65XV2	XB3_ORYSJ	E3 ubiquitin-protein ligase XB3	17172358	Rice XA21 binding protein 3 is a ubiquitin ligase required for full Xa21-mediated disease resistance.

O49686	PYR1_ARATH	Abscisic acid receptor PYR1	19898494	The abscisic acid receptor PYR1 in complex with abscisic acid.

O35394	PRAF1_RAT	Prenylated Rab acceptor protein 1	9341137	Isolation and characterization of a dual prenylated Rab and VAMP2 receptor.

Q55C62	CBPJ_DICDI	Calcium-binding protein J	15606490	Disruption of the NCS-1/frequenin-related ncsA gene in Dictyostelium discoideum accelerates development.

Q8CIZ9	NOX1_MOUSE	NADPH oxidase 1	12473664	Two novel proteins activate superoxide generation by the NADPH oxidase NOX1.

P01133	EGF_HUMAN	Pro-epidermal growth factor	3491360	Human epidermal growth factor precursor: cDNA sequence, expression in vitro and gene organization.

Q60997	DMBT1_MOUSE	Deleted in malignant brain tumors 1 protein	7876332	Characterization of the major sulfated protein of mouse pancreatic acinar cells: a high molecular weight peripheral membrane glycoprotein of zymogen granules.

P35269	T2FA_HUMAN	General transcription factor IIF subunit 1	1734284	A cDNA encoding RAP74, a general initiation factor for transcription by RNA polymerase II.

P40574	YAP5_YEAST	AP-1-like transcription factor YAP5	12464632	Complex transcriptional circuitry at the G1/S transition in Saccharomyces cerevisiae.

P53885	MDG1_YEAST	Signal transduction protein MDG1	8914522	Genetic interactions indicate a role for Mdg1p and the SH3 domain protein Bem1p in linking the G-protein mediated yeast pheromone signalling pathway to regulators of cell polarity.

Q07655	WHI4_YEAST	Protein WHI4	14562095	Global analysis of protein localization in budding yeast.

P13535	MYH8_HUMAN	Myosin-8	2373371	Generation of a full-length human perinatal myosin heavy-chain- encoding cDNA.

Q03834	MSH6_YEAST	DNA mismatch repair protein MSH6	8816473	The Saccharomyces cerevisiae Msh2 and Msh6 proteins form a complex that specifically binds to duplex oligonucleotides containing mismatched DNA base pairs.

Q99679	GPR21_HUMAN	Probable G-protein coupled receptor 21	9073069	Cloning and chromosomal mapping of four putative novel human G- protein-coupled receptor genes.

Q9Z0U4	GABR1_RAT	Gamma-aminobutyric acid type B receptor subunit 1	10457184	Alternative splicing generates a novel isoform of the rat metabotropic GABA(B)R1 receptor.

P52738	ZN140_HUMAN	Zinc finger protein 140	7557990	Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders.

O44249	PRP1_MANSE	Phenoloxidase subunit 1	16291091	Prophenoloxidase binds to the surface of hemocytes and is involved in hemocyte melanization in Manduca sexta.

Q06053	DUS3_YEAST	tRNA-dihydrouridine synthase 3	14562095	Global analysis of protein localization in budding yeast.

P55265	DSRAD_HUMAN	Double-stranded RNA-specific adenosine deaminase	9020165	Functionally distinct double-stranded RNA-binding domains associated with alternative splice site variants of the interferon-inducible double-stranded RNA-specific adenosine deaminase.

Q9Z2B3	RGR_MOUSE	RPE-retinal G protein-coupled receptor	9841934	Structure and developmental expression of the mouse RGR opsin gene.

P25336	MSH3_YEAST	DNA mismatch repair protein MSH3	8510668	The yeast gene MSH3 defines a new class of eukaryotic MutS homologues.

O75828	CBR3_HUMAN	Carbonyl reductase [NADPH] 3	9740676	Mapping of a novel human carbonyl reductase, CBR3, and ribosomal pseudogenes to human chromosome 21q22.2.

Q9V4F9	MED26_DROME	Mediator of RNA polymerase II transcription subunit 26	16751183	Coactivator cross-talk specifies transcriptional output.

Q8VBU2	NDRG2_RAT	Protein NDRG2	12072429	Characterization of rat NDRG2 (N-Myc downstream regulated gene 2), a novel early mineralocorticoid-specific induced gene.

P39998	EDC3_YEAST	Enhancer of mRNA-decapping protein 3	15020463	Identification of Edc3p as an enhancer of mRNA decapping in Saccharomyces cerevisiae.

P36059	YKP1_YEAST	Uncharacterized protein YKL151C	14562095	Global analysis of protein localization in budding yeast.

P36046	MIA40_YEAST	Mitochondrial intermembrane space import and assembly protein 40	15620710	Mia40, a novel factor for protein import into the intermembrane space of mitochondria is able to bind metal ions.

Q9XI00	SKI32_ARATH	F-box protein 7	17240087	The evolutionarily conserved Arabidopsis thaliana F-box protein AtFBP7 is required for efficient translation during temperature stress.

P06742	MLC1_DROME	Myosin light chain alkali	3106119	The indirect flight muscle of Drosophila accumulates a unique myosin alkali light chain isoform.

P19812	UBR1_YEAST	E3 ubiquitin-protein ligase UBR1	2209542	The recognition component of the N-end rule pathway.

Q2LKX9	IXOSN_IXOSI	Ixosin	16087274	A novel antimicrobial peptide from salivary glands of the hard tick, Ixodes sinensis.

O94534	ALP14_SCHPO	Spindle pole body component alp14	14742702	Interdependency of fission yeast Alp14/TOG and coiled coil protein Alp7 in microtubule localization and bipolar spindle formation.

P83436	COG7_HUMAN	Conserved oligomeric Golgi complex subunit 7	15107842	Mutation of the COG complex subunit gene COG7 causes a lethal congenital disorder.

P87074	RHP9_SCHPO	DNA repair protein rhp9	9153313	Isolation and characterization of the Schizosaccharomyces pombe rhp9 gene: a gene required for the DNA damage checkpoint but not the replication checkpoint.

P19334	TRP_DROME	Transient receptor potential protein	9215637	Coassembly of TRP and TRPL produces a distinct store-operated conductance.

Q62073	M3K7_MOUSE	Mitogen-activated protein kinase kinase kinase 7	12556533	Regulation of the interleukin-1-induced signaling pathways by a novel member of the protein phosphatase 2C family (PP2Cepsilon).

P32558	SPT16_YEAST	FACT complex subunit SPT16	10413469	Spt16 and Pob3 of Saccharomyces cerevisiae form an essential, abundant heterodimer that is nuclear, chromatin-associated, and copurifies with DNA polymerase alpha.

P39925	AFG3_YEAST	Mitochondrial respiratory chain complexes assembly protein AFG3	8681382	The YTA10-12 complex, an AAA protease with chaperone-like activity in the inner membrane of mitochondria.

P32495	NHP2_YEAST	H/ACA ribonucleoprotein complex subunit 2	9843512	Nhp2p and Nop10p are essential for the function of H/ACA snoRNPs.

P43246	MSH2_HUMAN	DNA mismatch repair protein Msh2	10856833	Identification of factors interacting with hMSH2 in the fetal liver utilizing the yeast two-hybrid system. In vivo interaction through the C-terminal domains of hEXO1 and hMSH2 and comparative expression analysis.

Q9U281	H332_CAEEL	Histone H3.3 type 2	16846252	Histone H3.3 variant dynamics in the germline of Caenorhabditis elegans.

Q12452	ERG27_YEAST	3-keto-steroid reductase	12119386	Protein-protein interactions among C-4 demethylation enzymes involved in yeast sterol biosynthesis.

P18266	GSK3B_RAT	Glycogen synthase kinase-3 beta	2164470	Molecular cloning and expression of glycogen synthase kinase-3/factor A.

Q12887	COX10_HUMAN	Protoheme IX farnesyltransferase, mitochondrial	8078902	Isolation of a human cDNA for heme A:farnesyltransferase by functional complementation of a yeast cox10 mutant.

P37236	FREQ_DROME	Frequenin-1	8101711	Frequenin -- a novel calcium-binding protein that modulates synaptic efficacy in the Drosophila nervous system.

Q61823	PDCD4_MOUSE	Programmed cell death protein 4	12482958	The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translation.

Q62751	IREB2_RAT	Iron-responsive element-binding protein 2	7665579	Iron regulates the intracellular degradation of iron regulatory protein 2 by the proteasome.

Q8BUE7	MUC20_MOUSE	Mucin-20	15314156	MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met.

Q9UBX7	KLK11_HUMAN	Kallikrein-11	9765601	cDNA cloning and expression of a novel serine protease, TLSP.

Q86IA3	PDI1_DICDI	Protein disulfide-isomerase 1	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P36164	TVP38_YEAST	Golgi apparatus membrane protein TVP38	16107716	Immunoisolaton of the yeast Golgi subcompartments and characterization of a novel membrane protein, Svp26, discovered in the Sed5-containing compartments.

P31016	DLG4_RAT	Disks large homolog 4	11134026	Sema4c, a transmembrane semaphorin, interacts with a post-synaptic density protein, PSD-95.

Q7BVH7	SSEB_SALTY	Secreted effector protein sseB	11567004	SseBCD proteins are secreted by the type III secretion system of Salmonella pathogenicity island 2 and function as a translocon.

Q9S756	FRI4_ARATH	Ferritin-4, chloroplastic	11672431	Structure and differential expression of the four members of the Arabidopsis thaliana ferritin gene family.

P46933	APBB1_RAT	Amyloid beta A4 precursor protein-binding family B member 1	19282473	Fe65 is required for Tip60-directed histone H4 acetylation at DNA strand breaks.

Q61955	KLK8_MOUSE	Kallikrein-8	12944500	NMDA-dependent proteolysis of presynaptic adhesion molecule L1 in the hippocampus by neuropsin.

Q9URV9	SRX1_SCHPO	Sulfiredoxin	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9SL02	RAD50_ARATH	DNA repair protein RAD50	11169180	Disruption of the Arabidopsis RAD50 gene leads to plant sterility and MMS sensitivity.

Q12126	CRK1_SCHPO	Serine/threonine-protein kinase crk1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9LSP7	UBC32_ARATH	Ubiquitin-conjugating enzyme E2 32	16339806	Genome analysis and functional characterization of the E2 and RING- type E3 ligase ubiquitination enzymes of Arabidopsis.

Q39255	SKP1A_ARATH	SKP1-like protein 1A	16446454	F-box-like domain in the polerovirus protein P0 is required for silencing suppressor function.

P25605	ILV6_YEAST	Acetolactate synthase small subunit, mitochondrial	10213630	Expression, purification, characterization, and reconstitution of the large and small subunits of yeast acetohydroxyacid synthase.

P38690	YHJ3_YEAST	Uncharacterized protein YHR033W	11914276	Subcellular localization of the yeast proteome.

P32485	HOG1_YEAST	Mitogen-activated protein kinase HOG1	16885417	The MAPK Hog1p modulates Fps1p-dependent arsenite uptake and tolerance in yeast.

Q287T7	MFRN1_DANRE	Mitoferrin-1	16511496	Mitoferrin is essential for erythroid iron assimilation.

O14979	HNRDL_HUMAN	Heterogeneous nuclear ribonucleoprotein D-like	10072754	Two forms of expression and genomic structure of the human heterogeneous nuclear ribonucleoprotein D-like JKTBP gene (HNRPDL).

Q9P6I7	ADA_SCHPO	Adenosine deaminase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q07813	BAX_MOUSE	Apoptosis regulator BAX	8358790	Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death.

Q04170	YD391_YEAST	Uncharacterized protein YDR391C	14562095	Global analysis of protein localization in budding yeast.

Q6NXW6	RAD17_MOUSE	Cell cycle checkpoint protein RAD17	15297881	Mutation of the mouse Rad17 gene leads to embryonic lethality and reveals a role in DNA damage-dependent recombination.

Q24238	APH4_DROME	Alkaline phosphatase 4	10628988	A novel Drosophila alkaline phosphatase specific to the ellipsoid body of the adult brain and the lower Malpighian (renal) tubule.

Q9Z110	P5CS_MOUSE	Delta-1-pyrroline-5-carboxylate synthase	10037775	Molecular enzymology of mammalian delta1-pyrroline-5-carboxylate synthase. Alternative splice donor utilization generates isoforms with different sensitivity to ornithine inhibition.

O42868	SSU72_SCHPO	RNA polymerase II subunit A C-terminal domain phosphatase ssu72	14617822	A comparative analysis of an orthologous proteomic environment in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe.

Q93ZH2	NFYA3_ARATH	Nuclear transcription factor Y subunit A-3	9662544	Multiple genes encoding the conserved CCAAT-box transcription factor complex are expressed in Arabidopsis.

Q63448	ACOX3_RAT	Peroxisomal acyl-coenzyme A oxidase 3	8706733	Rat pristanoyl-CoA oxidase. cDNA cloning and recognition of its C- terminal (SQL) by the peroxisomal-targeting signal 1 receptor.

Q70J99	UN13D_HUMAN	Protein unc-13 homolog D	17237785	Secretory cytotoxic granule maturation and exocytosis require the effector protein hMunc13-4.

P42748	UBC4_ARATH	Ubiquitin-conjugating enzyme E2 4	16339806	Genome analysis and functional characterization of the E2 and RING- type E3 ligase ubiquitination enzymes of Arabidopsis.

P43637	TOS3_YEAST	Serine/threonine-protein kinase TOS3	15879520	Role of Tos3, a Snf1 protein kinase kinase, during growth of Saccharomyces cerevisiae on nonfermentable carbon sources.

P53201	SWC4_YEAST	SWR1-complex protein 4	14690608	A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1.

P47013	DS1P1_YEAST	Dihydrosphingosine 1-phosphate phosphatase LCB3	9353337	Identification and characterization of Saccharomyces cerevisiae dihydrosphingosine-1-phosphate phosphatase.

P31397	MAP3_SCHPO	Pheromone M-factor receptor	8380233	Schizosaccharomyces pombe map3+ encodes the putative M-factor receptor.

Q94ID2	IPT5_ARATH	Adenylate isopentenyltransferase 5, chloroplastic	14726522	Distinct isoprenoid origins of cis- and trans-zeatin biosyntheses in Arabidopsis.

Q9UIF9	BAZ2A_HUMAN	Bromodomain adjacent to zinc finger domain protein 2A	10662543	A novel family of bromodomain genes.

Q08831	VTS1_YEAST	Protein VTS1	12858164	The RNA-binding SAM domain of Smaug defines a new family of post- transcriptional regulators.

Q13838	UAP56_HUMAN	Spliceosome RNA helicase BAT1	14667819	Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region.

P10506	BYR1_SCHPO	Protein kinase byr1	11683500	Bob1, a Gim5/MM-1/Pfd5 homolog, interacts with the MAP kinase kinase byr1 to regulate sexual differentiation in the fission yeast, Schizosaccharomyces pombe.

P28466	WNT5_DROME	Protein Wnt-5	11821428	Drosophila segment polarity gene product porcupine stimulates the posttranslational N-glycosylation of wingless in the endoplasmic reticulum.

Q8N693	ESX1_HUMAN	Homeobox protein ESX1	15235584	Paired-like homeodomain protein ESXR1 possesses a cleavable C- terminal region that inhibits cyclin degradation.

Q39102	FTSH1_ARATH	ATP-dependent zinc metalloprotease FTSH 1, chloroplastic	16040665	Functional redundancy of AtFtsH metalloproteases in thylakoid membrane complexes.

Q9LVI6	RLK90_ARATH	Probable inactive receptor kinase RLK902	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q9BYF1	ACE2_HUMAN	Angiotensin-converting enzyme 2	10969042	A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9.

Q06679	UTP4_YEAST	U3 small nucleolar RNA-associated protein 4	15489292	RNA polymerase I transcription and pre-rRNA processing are linked by specific SSU processome components.

Q12009	TRMB_YEAST	tRNA (guanine-N(7)-)-methyltransferase	12403464	Two proteins that form a complex are required for 7-methylguanosine modification of yeast tRNA.

O43526	KCNQ2_HUMAN	Potassium voltage-gated channel subfamily KQT member 2	9430594	A potassium channel mutation in neonatal human epilepsy.

P49427	UB2R1_HUMAN	Ubiquitin-conjugating enzyme E2 R1	8248134	Cloning of the human homolog of the CDC34 cell cycle gene by complementation in yeast.

P38979	RSSA_DROME	40S ribosomal protein SA	10022917	Down-regulation of RpS21, a putative translation initiation factor interacting with P40, produces viable minute imagos and larval lethality with overgrown hematopoietic organs and imaginal discs.

Q9HCK4	ROBO2_HUMAN	Roundabout homolog 2	9458045	Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors.

Q9FLP0	MA651_ARATH	65-kDa microtubule-associated protein 1	15273298	The Arabidopsis microtubule-associated protein AtMAP65-1: molecular analysis of its microtubule bundling activity.

P19320	VCAM1_HUMAN	Vascular cell adhesion protein 1	2688898	Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes.

Q17TI5	BRX_ARATH	Protein BREVIS RADIX	19201913	The short-rooted phenotype of the brevis radix mutant partly reflects root abscisic acid hypersensitivity.

P11540	BARS_BACAM	Barstar	9757110	Recognition of RNase Sa by the inhibitor barstar: structure of the complex at 1.7 A resolution.

Q9MA98	ERCC1_ARATH	DNA excision repair protein ERCC-1	12554710	Arabidopsis mutants sensitive to gamma radiation include the homologue of the human repair gene ERCC1.

Q13595	TRA2A_HUMAN	Transformer-2 protein homolog alpha	9546399	Human Tra2 proteins are sequence-specific activators of pre-mRNA splicing.

P36560	ASR_ECOLI	Acid shock protein	12670971	Molecular characterization of the acid-inducible asr gene of Escherichia coli and its role in acid stress response.

P02688	MBP_RAT	Myelin basic protein S	14580679	Identification and characterisation of a cDNA encoding a 17-kDa isoform of rat myelin basic protein.

O13790	CUL1_SCHPO	Cullin-1	10880460	Covalent modifier NEDD8 is essential for SCF ubiquitin-ligase in fission yeast.

O74880	MCES_SCHPO	mRNA cap guanine-N7 methyltransferase	10347220	Characterization of human, Schizosaccharomyces pombe, and Candida albicans mRNA cap methyltransferases and complete replacement of the yeast capping apparatus by mammalian enzymes.

P18669	PGAM1_HUMAN	Phosphoglycerate mutase 1	2846554	Sequence of the human erythrocyte phosphoglycerate mutase by microsequencer and mass spectrometry.

Q07794	RT109_YEAST	Histone acetyltransferase RTT109	17272722	Yeast Rtt109 promotes genome stability by acetylating histone H3 on lysine 56.

Q99314	SAS5_YEAST	Something about silencing protein 5	11731480	The silencing complex SAS-I links histone acetylation to the assembly of repressed chromatin by CAF-I and Asf1 in Saccharomyces cerevisiae.

Q63425	PRAX_RAT	Periaxin	12591166	Sensory neuron proteins interact with the intracellular domains of sodium channel NaV1.8.

P54105	ICLN_HUMAN	Methylosome subunit pICln	16087681	Toward an assembly line for U7 snRNPs: interactions of U7-specific Lsm proteins with PRMT5 and SMN complexes.

Q54Q48	Y5844_DICDI	Putative uncharacterized protein DDB_G0284097	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q14376	GALE_HUMAN	UDP-glucose 4-epimerase	16302980	Functional analysis of disease-causing mutations in human UDP- galactose 4-epimerase.

Q8N573	OXR1_HUMAN	Oxidation resistance protein 1	11114193	Functional genomics reveals a family of eukaryotic oxidation protection genes.

Q60760	GRB10_MOUSE	Growth factor receptor-bound protein 10	12771153	Two novel proteins that are linked to insulin-like growth factor (IGF-I) receptors by the Grb10 adapter and modulate IGF-I signaling.

Q91ZR5	CTSR1_MOUSE	Cation channel sperm-associated protein 1	14657352	CatSper1 required for evoked Ca2+ entry and control of flagellar function in sperm.

Q9V422	RYK2_DROME	Tyrosine-protein kinase Dnt	9858720	Embryonic expression and activity of doughnut, a second RYK homolog in Drosophila.

P54274	TERF1_HUMAN	Telomeric repeat-binding factor 1	11375976	Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks.

Q9P7F2	AMOH2_SCHPO	Putative primary amine oxidase 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q5ATH9	BXLB_EMENI	Exo-1,4-beta-xylosidase bxlB	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

O95825	QORL1_HUMAN	Quinone oxidoreductase-like protein 1	10191096	Identification of a zeta-crystallin (quinone reductase)-like 1 gene (CRYZL1) mapped to human chromosome 21q22.1.

Q08949	DDC1_YEAST	DNA damage checkpoint protein 1	9670034	Mec1p is essential for phosphorylation of the yeast DNA damage checkpoint protein Ddc1p, which physically interacts with Mec3p.

P38990	PAK1_YEAST	Serine/threonine-protein kinase PAK1	9341678	Overexpression of the protein kinase Pak1 suppresses yeast DNA polymerase mutations.

Q09790	APS1_SCHPO	Diphosphoinositol polyphosphate phosphohydrolase aps1	10090752	Schizosaccharomyces pombe Aps1, a diadenosine 5',5'''-P1, P6- hexaphosphate hydrolase that is a member of the nudix (MutT) family of hydrolases: cloning of the gene and characterization of the purified enzyme.

Q9W1L5	PAL2_DROME	Peptidyl-alpha-hydroxyglycine alpha-amidating lyase 2	15198673	Drosophila uses two distinct neuropeptide amidating enzymes, dPAL1 and dPAL2.

O43708	MAAI_HUMAN	Maleylacetoacetate isomerase	11327815	Crystal structure of maleylacetoacetate isomerase/glutathione transferase zeta reveals the molecular basis for its remarkable catalytic promiscuity.

P40348	RFC2_YEAST	Replication factor C subunit 2	11486023	Chl12 (Ctf18) forms a novel replication factor C-related complex and functions redundantly with Rad24 in the DNA replication checkpoint pathway.

Q10573	LIN25_CAEEL	Protein lin-25	7867931	lin-25, a gene required for vulval induction in Caenorhabditis elegans.

P10606	COX5B_HUMAN	Cytochrome c oxidase subunit 5B, mitochondrial	1646156	Structure of the human cytochrome c oxidase subunit Vb gene and chromosomal mapping of the coding gene and of seven pseudogenes.

Q8NCW5	AIBP_HUMAN	Apolipoprotein A-I-binding protein	11991719	Cloning and characterization of a novel apolipoprotein A-I-binding protein, AI-BP, secreted by cells of the kidney proximal tubules in response to HDL or ApoA-I.

Q96IV0	NGLY1_HUMAN	Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	15358861	A complex between peptide:N-glycanase and two proteasome-linked proteins suggests a mechanism for the degradation of misfolded glycoproteins.

O00712	NFIB_HUMAN	Nuclear factor 1 B-type	7590749	Chromosomal localization of the four genes (NFIA, B, C, and X) for the human transcription factor nuclear factor I by FISH.

P08630	BTKL_DROME	Tyrosine-protein kinase Btk29A	10330180	The Drosophila Bruton's tyrosine kinase (Btk) homolog is required for adult survival and male genital formation.

Q96533	ADHX_ARATH	Alcohol dehydrogenase class-3	12913179	Enhanced formaldehyde detoxification by overexpression of glutathione-dependent formaldehyde dehydrogenase from Arabidopsis.

Q84TI7	HKT1_ARATH	Sodium transporter HKT1	11698666	AtHKT1 is a salt tolerance determinant that controls Na(+) entry into plant roots.

Q9DCH6	ZFAN6_MOUSE	AN1-type zinc finger protein 6	11054541	Cloning and characterization of AWP1, a novel protein that associates with serine/threonine kinase PRK1 in vivo.

Q04067	EIF3G_YEAST	Eukaryotic translation initiation factor 3 subunit G	9671501	Identification of a translation initiation factor 3 (eIF3) core complex, conserved in yeast and mammals, that interacts with eIF5.

P32835	GSP1_YEAST	GTP-binding nuclear protein GSP1/CNR1	11589573	Overexpression of Bud5p can suppress mutations in the Gsp1p guanine nucleotide exchange factor Prp20p in Saccharomyces cerevisiae.

Q08211	DHX9_HUMAN	ATP-dependent RNA helicase A	9111062	Domain structure of human nuclear DNA helicase II (RNA helicase A).

O74957	AGO1_SCHPO	Protein argonaute	12193640	Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi.

P49023	PAXI_HUMAN	Paxillin	9054445	Monocyte cells and cancer cells express novel paxillin isoforms with different binding properties to focal adhesion proteins.

Q02749	YP068_YEAST	Uncharacterized protein YPL068C	14562095	Global analysis of protein localization in budding yeast.

Q12296	MAM3_YEAST	Protein MAM3	14562095	Global analysis of protein localization in budding yeast.

Q12389	DBP10_YEAST	ATP-dependent RNA helicase DBP10	10871363	Dbp10p, a putative RNA helicase from Saccharomyces cerevisiae, is required for ribosome biogenesis.

P56524	HDAC4_HUMAN	Histone deacetylase 4	10220385	Three proteins define a class of human histone deacetylases related to yeast Hda1p.

P38781	RSC30_YEAST	Chromatin structure-remodeling complex protein RSC30	12183366	Chromatin remodeling by RSC involves ATP-dependent DNA translocation.

P53286	BTN2_YEAST	Protein BTN2	11053386	The yeast model for Batten disease: mutations in BTN1, BTN2, and HSP30 alter pH homeostasis.

Q9UGP5	DPOLL_HUMAN	DNA polymerase lambda	10982892	Two novel human and mouse DNA polymerases of the polX family.

O74405	SET11_SCHPO	Ribosomal N-lysine methyltransferase set11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O60095	TGCE3_SCHPO	Probable lipase C14C8.15	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q62625	MLP3B_RAT	Microtubule-associated proteins 1A/1B light chain 3B	7908909	Molecular characterization of light chain 3. A microtubule binding subunit of MAP1A and MAP1B.

P51566	AFC1_ARATH	Serine/threonine-protein kinase AFC1	7991592	AFC1, a LAMMER kinase from Arabidopsis thaliana, activates STE12- dependent processes in yeast.

P0ACF4	DBHB_ECOLI	DNA-binding protein HU-beta	227733	Native Escherichia coli HU protein is a heterotypic dimer.

Q9FI61	UBC27_ARATH	Ubiquitin-conjugating enzyme E2 27	16339806	Genome analysis and functional characterization of the E2 and RING- type E3 ligase ubiquitination enzymes of Arabidopsis.

P03873	MBI2_YEAST	Cytochrome b mRNA maturase bI2	9872396	The complete sequence of the mitochondrial genome of Saccharomyces cerevisiae.

Q03976	RT24_YEAST	37S ribosomal protein S24, mitochondrial	11278769	Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues.

Q03518	TAP1_HUMAN	Antigen peptide transporter 1	11532960	Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing.

Q14802	FXYD3_HUMAN	FXYD domain-containing ion transport regulator 3	7836447	Mat-8, a novel phospholemman-like protein expressed in human breast tumors, induces a chloride conductance in Xenopus oocytes.

Q9JHL4	DBNL_RAT	Drebrin-like protein	11595038	Molecular cloning and dendritic localization of rat SH3P7.

Q92574	TSC1_HUMAN	Hamartin	9809973	Hamartin, the product of the tuberous sclerosis 1 (TSC1) gene, interacts with tuberin and appears to be localized to cytoplasmic vesicles.

P52907	CAZA1_HUMAN	F-actin-capping protein subunit alpha-1	9331217	Vertebrates have conserved capping protein alpha isoforms with specific expression patterns.

Q9R1T7	ICOS_RAT	Inducible T-cell costimulator	11006126	Identification and characterization of rat AILIM/ICOS, a novel T-cell costimulatory molecule, related to the CD28/CTLA4 family.

P50273	ATP22_YEAST	Mitochondrial translation factor ATP22	17110482	The Saccharomyces cerevisiae ATP22 gene codes for the mitochondrial ATPase subunit 6-specific translation factor.

Q9ERZ0	HEMGN_MOUSE	Hemogen	11404085	Hemogen is a novel nuclear factor specifically expressed in mouse hematopoietic development and its human homologue EDAG maps to chromosome 9q22, a region containing breakpoints of hematological neoplasms.

Q62230	SN_MOUSE	Sialoadhesin	11238599	CD43 functions as a T cell counterreceptor for the macrophage adhesion receptor sialoadhesin (Siglec-1).

O74356	YH16_SCHPO	Putative ATP-dependent RNA helicase C25D12.06	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O35142	COPB2_RAT	Coatomer subunit beta'	9360998	The coatomer protein beta'-COP, a selective binding protein (RACK) for protein kinase Cepsilon.

P53166	MRH4_YEAST	ATP-dependent RNA helicase MRH4, mitochondrial	12702275	A novel mitochondrial DEAD box protein (Mrh4) required for maintenance of mtDNA in Saccharomyces cerevisiae.

P33154	PR1_ARATH	Pathogenesis-related protein 1	1392589	Acquired resistance in Arabidopsis.

Q12031	ACEB_YEAST	Mitochondrial 2-methylisocitrate lyase	11092862	The Saccharomyces cerevisiae ICL2 gene encodes a mitochondrial 2- methylisocitrate lyase involved in propionyl-coenzyme A metabolism.

Q06496	NPT2A_RAT	Sodium-dependent phosphate transport protein 2A	8327470	Expression cloning of human and rat renal cortex Na/Pi cotransport.

Q2PFD7	PSD3_MOUSE	PH and SEC7 domain-containing protein 3	16707115	Distinct spatiotemporal expression of EFA6D, a guanine nucleotide exchange factor for ARF6, among the EFA6 family in mouse brain.

Q10173	NUF2_SCHPO	Kinetochore protein nuf2	11685532	A conserved protein, Nuf2, is implicated in connecting the centromere to the spindle during chromosome segregation: a link between the kinetochore function and the spindle checkpoint.

Q9PUK8	FZD7A_XENLA	Frizzled-7-A	11291855	Functional analysis of the Xenopus frizzled 7 protein domains using chimeric receptors.

O35316	SC6A6_MOUSE	Sodium- and chloride-dependent taurine transporter	9375654	Molecular characterization and in situ localization of a mouse retinal taurine transporter.

O94927	HAUS5_HUMAN	HAUS augmin-like complex subunit 5	19369198	The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells.

P05798	RNSA_STRAU	Guanyl-specific ribonuclease Sa	9757110	Recognition of RNase Sa by the inhibitor barstar: structure of the complex at 1.7 A resolution.

Q96EB6	SIRT1_HUMAN	NAD-dependent deacetylase sirtuin-1	16079181	Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins.

O75362	ZN217_HUMAN	Zinc finger protein 217	18625718	Genome analysis identifies the p15ink4b tumor suppressor as a direct target of the ZNF217/CoREST complex.

P53286	BTN2_YEAST	Protein BTN2	12615067	The yeast model for Batten disease: a role for Btn2p in the trafficking of the Golgi-associated vesicular targeting protein, Yif1p.

Q9Y4K3	TRAF6_HUMAN	TNF receptor-associated factor 6	16378096	Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling.

O65572	CCD1_ARATH	Carotenoid 9,10(9',10')-cleavage dioxygenase 1	16507088	Characterization of three members of the Arabidopsis carotenoid cleavage dioxygenase family demonstrates the divergent roles of this multifunctional enzyme family.

O94763	RMP_HUMAN	Unconventional prefoldin RPB5 interactor	9878255	Molecular cloning of a gene on chromosome 19q12 coding for a novel intracellular protein: analysis of expression in human and mouse tissues and in human tumor cells, particularly Reed-Sternberg cells in Hodgkin disease.

Q9Z2J4	NEXN_RAT	Nexilin	19881492	Nexilin mutations destabilize cardiac Z-disks and lead to dilated cardiomyopathy.

P28066	PSA5_HUMAN	Proteasome subunit alpha type-5	16251969	A heterodimeric complex that promotes the assembly of mammalian 20S proteasomes.

P61011	SRP54_HUMAN	Signal recognition particle 54 kDa protein	9511762	Protein SRP54 of human signal recognition particle: cloning, expression, and comparative analysis of functional sites.

Q13045	FLII_HUMAN	Protein flightless-1 homolog	9671805	TRIP: a novel double stranded RNA binding protein which interacts with the leucine rich repeat of flightless I.

O43044	NU120_SCHPO	Nucleoporin nup120	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P79398	IF4G2_RABIT	Eukaryotic translation initiation factor 4 gamma 2	9030685	A novel translational repressor mRNA is edited extensively in livers containing tumors caused by the transgene expression of the apoB mRNA- editing enzyme.

Q54U87	DHKA_DICDI	Hybrid signal transduction histidine kinase A	15897458	Peptide signaling during terminal differentiation of Dictyostelium.

Q92922	SMRC1_HUMAN	SWI/SNF complex subunit SMARCC1	11018012	Functional selectivity of recombinant mammalian SWI/SNF subunits.

Q14019	COTL1_HUMAN	Coactosin-like protein	11583571	Coactosin-like protein, a human F-actin-binding protein: critical role of lysine-75.

Q13761	RUNX3_HUMAN	Runt-related transcription factor 3	9751710	Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors.

P34972	CNR2_HUMAN	Cannabinoid receptor 2	7556170	Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations.

Q07418	PEX19_YEAST	Peroxisomal membrane protein import receptor PEX19	10637226	Saccharomyces cerevisiae Pex3p and Pex19p are required for proper localization and stability of peroxisomal membrane proteins.

P50993	AT1A2_HUMAN	Sodium/potassium-transporting ATPase subunit alpha-2	12539047	Haploinsufficiency of ATP1A2 encoding the Na+/K+ pump alpha2 subunit associated with familial hemiplegic migraine type 2.

O09106	HDAC1_MOUSE	Histone deacetylase 1	9271381	Identification of mouse histone deacetylase 1 as a growth factor- inducible gene.

P31107	DMS2_PHYBI	Adenoregulin	7842473	Effects of the amphiphilic peptides mastoparan and adenoregulin on receptor binding, G proteins, phosphoinositide breakdown, cyclic AMP generation, and calcium influx.

P19338	NUCL_HUMAN	Nucleolin	8321232	Nuclear proteins that bind the pre-mRNA 3' splice site sequence r(UUAG/G) and the human telomeric DNA sequence d(TTAGGG)n.

Q96DW6	S2538_HUMAN	Solute carrier family 25 member 38	19412178	Mutations in mitochondrial carrier family gene SLC25A38 cause nonsyndromic autosomal recessive congenital sideroblastic anemia.

Q99569	PKP4_HUMAN	Plakophilin-4	8937994	Cloning and characterization of a new armadillo family member, p0071, associated with the junctional plaque: evidence for a subfamily of closely related proteins.

Q9H4I2	ZHX3_HUMAN	Zinc fingers and homeoboxes protein 3	12659632	Analysis of zinc-fingers and homeoboxes (ZHX)-1-interacting proteins: molecular cloning and characterization of a member of the ZHX family, ZHX3.

Q8WZK3	IBP1_SCHPO	Dual specificity phosphatase ibp1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q54KF1	FORC_DICDI	Formin-C	12538772	ForC, a novel type of formin family protein lacking an FH1 domain, is involved in multicellular development in Dictyostelium discoideum.

Q99732	LITAF_HUMAN	Lipopolysaccharide-induced tumor necrosis factor-alpha factor	15064722	WWOX binds the specific proline-rich ligand PPXY: identification of candidate interacting proteins.

Q9V3L1	NDST_DROME	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase	10421372	Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signalling.

P54660	PONA_DICDI	Ponticulin	8089176	Ponticulin is the major high affinity link between the plasma membrane and the cortical actin network in Dictyostelium.

P97698	SMO_RAT	Smoothened homolog	8906787	The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog.

Q6DT37	MRCKG_HUMAN	Serine/threonine-protein kinase MRCK gamma	15194684	Expression of the human myotonic dystrophy kinase-related Cdc42- binding kinase gamma is regulated by promoter DNA methylation and Sp1 binding.

P49747	COMP_HUMAN	Cartilage oligomeric matrix protein	7713493	Characterization of human and mouse cartilage oligomeric matrix protein.

Q9JK45	KCNQ5_MOUSE	Potassium voltage-gated channel subfamily KQT member 5	15963599	The KCNQ5 potassium channel from mouse: a broadly expressed M-current like potassium channel modulated by zinc, pH, and volume changes.

Q945S5	CAX4_ARATH	Vacuolar cation/proton exchanger 4	16244156	Increased calcium levels and prolonged shelf life in tomatoes expressing Arabidopsis H+/Ca2+ transporters.

Q5ARE6	RHGA_EMENI	Rhamnogalacturonase A	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

P07195	LDHB_HUMAN	L-lactate dehydrogenase B chain	8314553	Analysis of a genetic mutation in an electrophoretic variant of the human lactate dehydrogenase-B(H) subunit.

Q9GS00	CSN1_CAEEL	COP9 signalosome complex subunit 1	12781129	Neddylation and deneddylation of CUL-3 is required to target MEI- 1/katanin for degradation at the meiosis-to-mitosis transition in C. elegans.

Q9QUP4	CHST5_MOUSE	Carbohydrate sulfotransferase 5	12218059	Enzymatic synthesis in vitro of the disulfated disaccharide unit of corneal keratan sulfate.

Q9UI95	MD2L2_HUMAN	Mitotic spindle assembly checkpoint protein MAD2B	10366450	Characterization of MAD2B and other mitotic spindle checkpoint genes.

Q53H47	SETMR_HUMAN	Histone-lysine N-methyltransferase SETMAR	9461395	Molecular evolution of an ancient mariner transposon, Hsmar1, in the human genome.

Q92611	EDEM1_HUMAN	ER degradation-enhancing alpha-mannosidase-like 1	19934218	A dual role for EDEM1 in the processing of rod opsin.

O74805	MYO51_SCHPO	Myosin-51	11112691	Two type V myosins with non-overlapping functions in the fission yeast Schizosaccharomyces pombe: Myo52 is concerned with growth polarity and cytokinesis, Myo51 is a component of the cytokinetic actin ring.

Q13751	LAMB3_HUMAN	Laminin subunit beta-3	19275936	ECM1 interacts with fibulin-3 and the beta 3 chain of laminin 332 through its serum albumin subdomain-like 2 domain.

P49798	RGS4_HUMAN	Regulator of G-protein signaling 4	8602223	Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family.

P38704	STP2_YEAST	Transcription factor STP2	10648791	Stp1p, Stp2p and Abf1p are involved in regulation of expression of the amino acid transporter gene BAP3 of Saccharomyces cerevisiae.

Q9GZU7	CTDS1_HUMAN	Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1	10967134	Complete nucleotide sequence and genomic structure of the human NRAMP1 gene region on chromosome region 2q35.

P23471	PTPRZ_HUMAN	Receptor-type tyrosine-protein phosphatase zeta	9653645	Molecular cloning and expression analysis of five novel genes in chromosome 1p36.

P86164	FA321_LITFA	Fallaxidin-3.2.1	18803332	The fallaxidin peptides from the skin secretion of the eastern dwarf tree frog Litoria fallax. Sequence determination by positive and negative ion electrospray mass spectrometry: antimicrobial activity and cDNA cloning of the fallaxidins.

O88280	SLIT3_RAT	Slit homolog 3 protein	11754167	Spatiotemporal expression patterns of slit and robo genes in the rat brain.

Q10585	SPD1_SCHPO	S-phase delaying protein 1	8887552	A novel S phase inhibitor in fission yeast.

P19334	TRP_DROME	Transient receptor potential protein	10896160	TRPgamma, a Drosophila TRP-related subunit, forms a regulated cation channel with TRPL.

P18581	CTR2_MOUSE	Low affinity cationic amino acid transporter 2	8385111	Identification of a low affinity, high capacity transporter of cationic amino acids in mouse liver.

P10244	MYBB_HUMAN	Myb-related protein B	10770937	Direct transactivation of the anti-apoptotic gene apolipoprotein J (clusterin) by B-MYB.

Q15311	RBP1_HUMAN	RalA-binding protein 1	10924126	Novel function of human RLIP76: ATP-dependent transport of glutathione conjugates and doxorubicin.

P83169	PLMN_STRCA	Plasminogen	11435135	Purification and partial characterisation of alpha(2)-antiplasmin and plasmin(ogen) from ostrich plasma.

Q14088	RB33A_HUMAN	Ras-related protein Rab-33A	7688322	Molecular cloning of a cDNA encoding a novel small GTP-binding protein.

P0CAT2	S238B_DANRE	Solute carrier family 25 member 38-B	19412178	Mutations in mitochondrial carrier family gene SLC25A38 cause nonsyndromic autosomal recessive congenital sideroblastic anemia.

Q9P7P0	YOL4_SCHPO	Uncharacterized acyltransferase C1718.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q5B153	GANA_EMENI	Arabinogalactan endo-1,4-beta-galactosidase A	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

Q6IA69	NADE_HUMAN	Glutamine-dependent NAD(+) synthetase	12547821	Molecular identification of human glutamine- and ammonia-dependent NAD synthetases. Carbon-nitrogen hydrolase domain confers glutamine dependency.

Q13315	ATM_HUMAN	Serine-protein kinase ATM	12556884	DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation.

P39304	ULAD_ECOLI	3-keto-L-gulonate-6-phosphate decarboxylase ulaD	14996803	Regulation of expression of the divergent ulaG and ulaABCDEF operons involved in L-ascorbate dissimilation in Escherichia coli.

Q9D8V0	HM13_MOUSE	Minor histocompatibility antigen H13	12972007	Expression of the presenilin-like signal peptide peptidase (SPP) in mouse adult brain and during development.

Q9ZU11	ATB15_ARATH	Homeobox-leucine zipper protein ATHB-15	15773855	microRNA-directed cleavage of ATHB15 mRNA regulates vascular development in Arabidopsis inflorescence stems.

P22680	CP7A1_HUMAN	Cholesterol 7-alpha-monooxygenase	2384150	Molecular cloning and sequence analysis of cDNA encoding human cholesterol 7 alpha-hydroxylase.

Q19266	KPC3_CAEEL	Protein kinase C-like 3	15151982	PAR-3 is required for epithelial cell polarity in the distal spermatheca of C. elegans.

Q9H171	ZBP1_HUMAN	Z-DNA-binding protein 1	11842111	Complex regulation of the human gene for the Z-DNA binding protein DLM-1.

P43254	COP1_ARATH	E3 ubiquitin-protein ligase COP1	12887588	The SPA1-like proteins SPA3 and SPA4 repress photomorphogenesis in the light.

Q38857	XTH22_ARATH	Xyloglucan endotransglucosylase/hydrolase protein 22	9414546	Cellular localization of Arabidopsis xyloglucan endotransglycosylase- related proteins during development and after wind stimulation.

P23721	SERC_ECOLI	Phosphoserine aminotransferase	3518706	The serC-aro A operon of Escherichia coli. A mixed function operon encoding enzymes from two different amino acid biosynthetic pathways.

Q12464	RUVB2_YEAST	RuvB-like protein 2	11278922	Rvb1p and Rvb2p are essential components of a chromatin remodeling complex that regulates transcription of over 5% of yeast genes.

O55156	CLIP2_RAT	CAP-Gly domain-containing linker protein 2	9427243	CLIP-115, a novel brain specific cytoplasmic linker protein, mediates the localisation of dendritic lamellar bodies.

Q53HL2	BOREA_HUMAN	Borealin	16239925	Survivin mediates targeting of the chromosomal passenger complex to the centromere and midbody.

P51163	HEM4_MOUSE	Uroporphyrinogen-III synthase	7607680	Uroporphyrinogen-III synthase: molecular cloning, nucleotide sequence, expression of a mouse full-length cDNA, and its localization on mouse chromosome 7.

Q8K400	STXB5_MOUSE	Syntaxin-binding protein 5	12832401	Tomosyn interacts with the t-SNAREs syntaxin4 and SNAP23 and plays a role in insulin-stimulated GLUT4 translocation.

Q14207	NPAT_HUMAN	Protein NPAT	17163457	HiNF-P is a bifunctional regulator of cell cycle controlled histone H4 gene transcription.

Q4V5A3	UNPG_DROME	Homeobox protein unplugged	12702651	An urbilaterian origin of the tripartite brain: developmental genetic insights from Drosophila.

O74489	QOR_SCHPO	Probable quinone oxidoreductase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O00628	PEX7_HUMAN	Peroxisomal targeting signal 2 receptor	9090381	Human PEX7 encodes the peroxisomal PTS2 receptor and is responsible for rhizomelic chondrodysplasia punctata.

O14443	GPN3_SCHPO	GPN-loop GTPase 3 homolog fet5	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9ERG0	LIMA1_MOUSE	LIM domain and actin-binding protein 1	11179679	Characterization of mouse epithelial protein lost in neoplasm (EPLIN) and comparison of mammalian and zebrafish EPLIN.

P00173	CYB5_RAT	Cytochrome b5	9245704	Identification of two homologous cytochrome b5s in rat brain.

Q925N6	IGSF1_RAT	Immunoglobulin superfamily member 1	11266515	Inhibin binding protein in rats: alternative transcripts and regulation in the pituitary across the estrous cycle.

Q9LT47	FIE_ARATH	Polycomb group protein FERTILIZATION-INDEPENDENT ENDOSPERM	10962025	Expression and parent-of-origin effects for FIS2, MEA, and FIE in the endosperm and embryo of developing Arabidopsis seeds.

P31016	DLG4_RAT	Disks large homolog 4	9756850	BEGAIN (brain-enriched guanylate kinase-associated protein), a novel neuronal PSD-95/SAP90-binding protein.

P15336	ATF2_HUMAN	Cyclic AMP-dependent transcription factor ATF-2	9748258	Characterization of functional domains of an embryonic stem cell coactivator UTF1 which are conserved and essential for potentiation of ATF-2 activity.

Q9NQC3	RTN4_HUMAN	Reticulon-4	19665976	A class of dynamin-like GTPases involved in the generation of the tubular ER network.

P33897	ABCD1_HUMAN	ATP-binding cassette sub-family D member 1	10551832	Homo- and heterodimerization of peroxisomal ATP-binding cassette half-transporters.

P77245	MURR_ECOLI	HTH-type transcriptional regulator murR	18723630	The transcriptional factors MurR and catabolite activator protein regulate N-acetylmuramic acid catabolism in Escherichia coli.

Q9V969	GR57A_DROME	Putative gustatory receptor 57a	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

Q8IXI1	MIRO2_HUMAN	Mitochondrial Rho GTPase 2	16630562	The atypical Rho GTPases Miro-1 and Miro-2 have essential roles in mitochondrial trafficking.

Q9QZR5	HIPK2_MOUSE	Homeodomain-interacting protein kinase 2	15082531	Wnt-1 signal induces phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK.

P15385	KCNA4_RAT	Potassium voltage-gated channel subfamily A member 4	16504945	The epilepsy-linked Lgi1 protein assembles into presynaptic Kv1 channels and inhibits inactivation by Kvbeta1.

P53845	YIF1_YEAST	Protein transport protein YIF1	10970842	A novel Golgi membrane protein is part of a GTPase-binding protein complex involved in vesicle targeting.

Q9BUP3	HTAI2_HUMAN	Oxidoreductase HTATIP2	10611237	Alternatively spliced products CC3 and TC3 have opposing effects on apoptosis.

O74953	YJC7_SCHPO	Uncharacterized protein C736.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q99222	AFI1_YEAST	ARF3-interacting protein 1	14515169	YOR129c, a new element interacting with Cnm67p, a component of the spindle pole body of Saccharomyces cerevisiae.

Q940H6	SRK2E_ARATH	Serine/threonine-protein kinase SRK2E	16959575	Plant stomata function in innate immunity against bacterial invasion.

Q12778	FOXO1_HUMAN	Forkhead box protein O1	11311120	The kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation site.

Q69ZI1	SH3R1_MOUSE	Putative E3 ubiquitin-protein ligase SH3RF1	16230351	Siah1 interacts with the scaffold protein POSH to promote JNK activation and apoptosis.

Q05949	BUR2_YEAST	Protein BUR2	16040246	BUR kinase selectively regulates H3 K4 trimethylation and H2B ubiquitylation through recruitment of the PAF elongation complex.

Q9WTL8	BMAL1_MOUSE	Aryl hydrocarbon receptor nuclear translocator-like protein 1	9704006	Transcriptionally active heterodimer formation of an Arnt-like PAS protein, Arnt3, with HIF-1a, HLF, and clock.

O15392	BIRC5_HUMAN	Baculoviral IAP repeat-containing protein 5	11069302	Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin.

P43574	GAT1_YEAST	Transcriptional regulatory protein GAT1	8622686	Gat1p, a GATA family protein whose production is sensitive to nitrogen catabolite repression, participates in transcriptional activation of nitrogen-catabolic genes in Saccharomyces cerevisiae.

P61328	FGF12_HUMAN	Fibroblast growth factor 12	8790420	Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development.

Q4TU14	RHF1A_ARATH	E3 ubiquitin-protein ligase RHF1A	18552199	Targeted degradation of the cyclin-dependent kinase inhibitor ICK4/KRP6 by RING-type E3 ligases is essential for mitotic cell cycle progression during Arabidopsis gametogenesis.

O14161	CWC21_SCHPO	Pre-mRNA-splicing factor cwc21	11884590	Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

Q9QXU8	DC1L1_RAT	Cytoplasmic dynein 1 light intermediate chain 1	10545494	Direct interaction of pericentrin with cytoplasmic dynein light intermediate chain contributes to mitotic spindle organization.

Q810Y4	CONA1_RAT	Collagen alpha-1(XXIII) chain	12644459	Type XXIII collagen, a new transmembrane collagen identified in metastatic tumor cells.

O59836	HIM1_SCHPO	Hsk1-interacting molecule 1	10409743	A fission yeast gene, him1(+)/dfp1(+), encoding a regulatory subunit for Hsk1 kinase, plays essential roles in S-phase initiation as well as in S-phase checkpoint control and recovery from DNA damage.

Q8WY21	SORC1_HUMAN	VPS10 domain-containing receptor SorCS1	11499680	The genes for the human VPS10 domain-containing receptors are large and contain many small exons.

P84045	H4_TIGCA	Histone H4	1840514	An H3-H4 histone gene pair in the marine copepod Tigriopus californicus, contains an intergenic dyad symmetry element.

Q04082	GPI19_YEAST	Phosphatidylinositol N-acetylglucosaminyltransferase subunit GPI19	14562095	Global analysis of protein localization in budding yeast.

Q9P0M2	AKA7G_HUMAN	A-kinase anchor protein 7 isoform gamma	10613906	Alternative splicing regulates the subcellular localization of A- kinase anchoring protein 18 isoforms.

Q9BVA6	FICD_HUMAN	Adenosine monophosphate-protein transferase FICD	19362538	The fic domain: regulation of cell signaling by adenylylation.

Q16281	CNGA3_HUMAN	Cyclic nucleotide-gated cation channel alpha-3	9662398	Total colourblindness is caused by mutations in the gene encoding the alpha-subunit of the cone photoreceptor cGMP-gated cation channel.

P07998	RNAS1_HUMAN	Ribonuclease pancreatic	8049276	Nucleotide sequence encoding human pancreatic ribonuclease.

P75908	YCDT_ECOLI	Probable diguanylate cyclase YcdT	18713317	The RNA binding protein CsrA controls cyclic di-GMP metabolism by directly regulating the expression of GGDEF proteins.

P25171	RCC1_DROME	Regulator of chromosome condensation	12121620	Ran localizes around the microtubule spindle in vivo during mitosis in Drosophila embryos.

Q8IR79	LIMK1_DROME	LIM domain kinase 1	11027607	A Drosophila homolog of LIM-kinase phosphorylates cofilin and induces actin cytoskeletal reorganization.

Q9W415	WUHO_DROME	tRNA (guanine-N(7)-)-methyltransferase subunit wuho	16762337	A new Drosophila gene wh (wuho) with WD40 repeats is essential for spermatogenesis and has maximal expression in hub cells.

Q53080	PSA1_RHOER	Proteasome subunit alpha 1	9000518	Subunit topology of the Rhodococcus proteasome.

P10619	PPGB_HUMAN	Lysosomal protective protein	3136930	Expression of cDNA encoding the human 'protective protein' associated with lysosomal beta-galactosidase and neuraminidase: homology to yeast proteases.

Q15291	RBBP5_HUMAN	Retinoblastoma-binding protein 5	15199122	Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression.

Q924X6	LRP8_MOUSE	Low-density lipoprotein receptor-related protein 8	11294845	Alternative splicing in the ligand binding domain of mouse ApoE receptor-2 produces receptor variants binding reelin but not alpha2- macroglobulin.

P34222	PTH2_YEAST	Peptidyl-tRNA hydrolase 2	12799450	Peptidyl-tRNA hydrolase from Sulfolobus solfataricus.

P81069	GABP2_MOUSE	GA-binding protein subunit beta-2	7958862	Molecular and genetic characterization of GABP beta.

Q18825	BAR1_CAEEL	Beta-catenin/armadillo-related protein 1	12023307	The axin-like protein PRY-1 is a negative regulator of a canonical Wnt pathway in C. elegans.

P53834	HCH1_YEAST	Hsp90 co-chaperone HCH1	14562095	Global analysis of protein localization in budding yeast.

Q13231	CHIT1_HUMAN	Chitotriosidase-1	7836450	Purification and characterization of human chitotriosidase, a novel member of the chitinase family of proteins.

Q9NZU7	CABP1_HUMAN	Calcium-binding protein 1	15980432	Molecular mechanism for divergent regulation of Cav1.2 Ca2+ channels by calmodulin and Ca2+-binding protein-1.

Q99828	CIB1_HUMAN	Calcium and integrin-binding protein 1	15475008	Calcium binding sequences in calmyrin regulates interaction with presenilin-2.

Q9P7J5	YJNA_SCHPO	Uncharacterized AAA domain-containing protein C24B10.10c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q99570	PI3R4_HUMAN	Phosphoinositide 3-kinase regulatory subunit 4	8999962	Characterization of p150, an adaptor protein for the human phosphatidylinositol (PtdIns) 3-kinase. Substrate presentation by phosphatidylinositol transfer protein to the p150.PtdIns 3-kinase complex.

Q09XV5	CHD8_MOUSE	Chromodomain-helicase-DNA-binding protein 8	16949368	CTCF-dependent chromatin insulator is linked to epigenetic remodeling.

Q8R2G6	CCD80_MOUSE	Coiled-coil domain-containing protein 80	18757743	Transcriptome-based systematic identification of extracellular matrix proteins.

Q8NK90	ABFA_ASPKA	Alpha-N-arabinofuranosidase A	16233515	Role of two alpha-L-arabinofuranosidases in arabinoxylan degradation and characteristics of the encoding genes from shochu koji molds, Aspergillus kawachii and Aspergillus awamori.

P31040	DHSA_HUMAN	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	7550341	Mutation of a nuclear succinate dehydrogenase gene results in mitochondrial respiratory chain deficiency.

Q12908	NTCP2_HUMAN	Ileal sodium/bile acid cotransporter	9109432	Primary bile acid malabsorption caused by mutations in the ileal sodium-dependent bile acid transporter gene (SLC10A2).

P33335	SGE1_YEAST	Protein SGE1	9483795	The Sge1 protein of Saccharomyces cerevisiae is a membrane-associated multidrug transporter.

O70244	CUBN_RAT	Cubilin	15616221	Expression and role of cubilin in the internalization of nutrients during the peri-implantation development of the rodent embryo.

O75689	ADAP1_HUMAN	Arf-GAP with dual PH domain-containing protein 1	10333475	Identification of centaurin-alpha1 as a potential in vivo phosphatidylinositol 3,4,5-trisphosphate-binding protein that is functionally homologous to the yeast ADP-ribosylation factor (ARF) GTPase-activating protein, Gcs1.

Q9GPM4	PGK_DICDI	Phosphoglycerate kinase	15363631	Calmodulin binds to and inhibits the activity of phosphoglycerate kinase.

Q9Y5K5	UCHL5_HUMAN	Ubiquitin carboxyl-terminal hydrolase isozyme L5	18922472	Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex.

Q9UUH5	YKI7_SCHPO	Uncharacterized protein C630.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9BSI4	TINF2_HUMAN	TERF1-interacting nuclear factor 2	15383534	Telosome, a mammalian telomere-associated complex formed by multiple telomeric proteins.

O55096	DPP3_RAT	Dipeptidyl peptidase 3	10387075	The HELLGH motif of rat liver dipeptidyl peptidase III is involved in zinc coordination and the catalytic activity of the enzyme.

P53088	CTU1_YEAST	Cytoplasmic tRNA 2-thiolation protein 1	19151091	Mechanistic characterization of the sulfur-relay system for eukaryotic 2-thiouridine biogenesis at tRNA wobble positions.

Q68EK9	CDC26_DANRE	Anaphase-promoting complex subunit CDC26	17141209	The anaphase-promoting complex is required in both dividing and quiescent cells during zebrafish development.

P40548	SNL1_YEAST	HSP70 co-chaperone SNL1	12105220	Prediction of novel Bag-1 homologs based on structure/function analysis identifies Snl1p as an Hsp70 co-chaperone in Saccharomyces cerevisiae.

Q9Z2F6	BCL3_MOUSE	B-cell lymphoma 3 protein homolog	16713561	Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling.

P53865	CNM67_YEAST	Chaotic nuclear migration protein 67	11742972	Prospore membrane formation linked to the leading edge protein (LEP) coat assembly.

Q8WWR8	NEUR4_HUMAN	Sialidase-4	14962670	Molecular cloning and characterization of NEU4, the fourth member of the human sialidase gene family.

Q9CZN4	SHSA9_MOUSE	Protein shisa-9	20185686	CKAMP44: A brain-specific protein attenuating short-term synaptic plasticity in the dentate gyrus.

P49089	ASNS1_YEAST	Asparagine synthetase [glutamine-hydrolyzing] 1	8951815	Cloning of the ASN1 and ASN2 genes encoding asparagine synthetases in Saccharomyces cerevisiae: differential regulation by the CCAAT-box- binding factor.

Q9LV85	CPR5_ARATH	Protein CPR-5	9338960	The cpr5 mutant of Arabidopsis expresses both NPR1-dependent and NPR1-independent resistance.

P32461	DPH2_YEAST	Diphthamide biosynthesis protein 2	15485916	Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2.

P56403	AQP7_RAT	Aquaporin-7	9252401	Cloning and functional expression of a new water channel abundantly expressed in the testis permeable to water, glycerol, and urea.

P47084	YJX3_YEAST	Uncharacterized protein YJR003C, mitochondrial	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

P32350	KNS1_YEAST	Dual specificity protein kinase KNS1	1910150	The KNS1 gene of Saccharomyces cerevisiae encodes a nonessential protein kinase homologue that is distantly related to members of the CDC28/cdc2 gene family.

Q12030	TAF10_YEAST	Transcription initiation factor TFIID subunit 10	8662725	Isolation and characterization of TAF25, an essential yeast gene that encodes an RNA polymerase II-specific TATA-binding protein-associated factor.

P08928	LAM0_DROME	Lamin Dm0	15054108	The lamin B receptor of Drosophila melanogaster.

Q12071	VPS54_YEAST	Vacuolar protein sorting-associated protein 54	12377769	Vps51p links the VFT complex to the SNARE Tlg1p.

Q9QYF3	MYO5A_RAT	Myosin-Va	10920234	Identification of a novel myosin-Va mutation in an ataxic mutant rat, dilute-opisthotonus.

Q9Y7X8	ARP5_SCHPO	Actin-like protein arp5	19040720	Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment.

P83673	LYS1_CRAVI	Lysozyme 1	15364284	Purification and characterization of lysozyme from plasma of the eastern oyster (Crassostrea virginica).

P46889	FTSK_ECOLI	DNA translocase ftsK	7592387	A new Escherichia coli cell division gene, ftsK.

Q4KL25	TMHS_MOUSE	Tetraspan membrane protein of hair cell stereocilia	15905332	A missense mutation in the previously undescribed gene Tmhs underlies deafness in hurry-scurry (hscy) mice.

P49746	TSP3_HUMAN	Thrombospondin-3	7558000	Structure and organization of the human thrombospondin 3 gene (THBS3).

Q9CAB6	UEV1B_ARATH	Ubiquitin-conjugating enzyme E2 variant 1B	18178771	Arabidopsis UEV1D promotes lysine-63-linked polyubiquitination and is involved in DNA damage response.

P33124	ACSL6_RAT	Long-chain-fatty-acid--CoA ligase 6	1569043	Cloning and functional expression of a novel long-chain acyl-CoA synthetase expressed in brain.

O15551	CLD3_HUMAN	Claudin-3	9441748	Analysis of a human gene homologous to rat ventral prostate.1 protein.

Q8C6A8	BHE22_MOUSE	Class E basic helix-loop-helix protein 22	12213201	Functional and structural characterization of the human gene BHLHB5, encoding a basic helix-loop-helix transcription factor.

Q5RJI5	BRSK1_MOUSE	BR serine/threonine-protein kinase 1	15705853	Mammalian SAD kinases are required for neuronal polarization.

P16143	PO2F1_XENLA	POU domain, class 2, transcription factor 1	7542467	Dynamic and differential Oct-1 expression during early Xenopus embryogenesis: persistence of Oct-1 protein following down-regulation of the RNA.

P35691	TCTP_YEAST	Translationally-controlled tumor protein homolog	16702403	Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes.

P14866	HNRPL_HUMAN	Heterogeneous nuclear ribonucleoprotein L	18669861	Regulation of CD45 alternative splicing by heterogeneous ribonucleoprotein, hnRNPLL.

Q9SKG5	SERK4_ARATH	Somatic embryogenesis receptor kinase 4	18667726	Arabidopsis SOMATIC EMBRYOGENESIS RECEPTOR KINASE proteins serve brassinosteroid-dependent and -independent signaling pathways.

Q99380	OST4_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST4	12810948	Determination of the membrane topology of Ost4p and its subunit interactions in the oligosaccharyltransferase complex in Saccharomyces cerevisiae.

P23469	PTPRE_HUMAN	Receptor-type tyrosine-protein phosphatase epsilon	8618876	Identification of a cytoplasmic, phorbol ester-inducible isoform of protein tyrosine phosphatase epsilon.

P08082	CLCB_RAT	Clathrin light chain B	3563513	Clathrin light chains LCA and LCB are similar, polymorphic, and share repeated heptad motifs.

Q05940	VMAT2_HUMAN	Synaptic vesicular amine transporter	8095030	A human synaptic vesicle monoamine transporter cDNA predicts posttranslational modifications, reveals chromosome 10 gene localization and identifies TaqI RFLPs.

P25118	TNR1A_MOUSE	Tumor necrosis factor receptor superfamily member 1A	1645445	Molecular cloning and expression of the type 1 and type 2 murine receptors for tumor necrosis factor.

Q9VUF8	CP314_DROME	Ecdysone 20-monooxygenase	12676319	Regulation of glial cell number and differentiation by ecdysone and Fos signaling.

Q4VBE4	EGFLA_MOUSE	Pikachurin	18757743	Transcriptome-based systematic identification of extracellular matrix proteins.

Q96BI3	APH1A_HUMAN	Gamma-secretase subunit APH-1A	12297508	Mammalian APH-1 interacts with presenilin and nicastrin and is required for intramembrane proteolysis of amyloid-beta precursor protein and Notch.

O80871	P2C25_ARATH	Probable protein phosphatase 2C 25	17630279	The PP2C-type phosphatase AP2C1, which negatively regulates MPK4 and MPK6, modulates innate immunity, jasmonic acid, and ethylene levels in Arabidopsis.

P01095	IPB2_YEAST	Protease B inhibitors 2 and 1	2015812	The proteinase yscB inhibitor (PB12) gene of yeast and studies on the function of its protein product.

Q03178	PIR1_YEAST	Cell wall mannoprotein PIR1	9192695	Stress proteins on the yeast cell surface determine resistance to osmotin, a plant antifungal protein.

O94450	YFF4_SCHPO	UPF0616 protein C1687.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P84700	CONO_CONGA	Conophan gld-V	15853325	Polypeptide chains containing D-gamma-hydroxyvaline.

Q9Y2H1	ST38L_HUMAN	Serine/threonine-protein kinase 38-like	15037617	Regulation of NDR2 protein kinase by multi-site phosphorylation and the S100B calcium-binding protein.

P43586	LOC1_YEAST	60S ribosomal subunit assembly/export protein LOC1	11309412	An exclusively nuclear RNA-binding protein affects asymmetric localization of ASH1 mRNA and Ash1p in yeast.

Q96AP0	ACD_HUMAN	Adrenocortical dysplasia protein homolog	19648609	OB fold-containing protein 1 (OBFC1), a human homolog of yeast Stn1, associates with TPP1 and is implicated in telomere length regulation.

O94435	MUG35_SCHPO	Meiotically up-regulated gene 35 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9ERH7	HIPK3_MOUSE	Homeodomain-interacting protein kinase 3	11034606	FIST/HIPK3: a Fas/FADD-interacting serine/threonine kinase that induces FADD phosphorylation and inhibits Fas-mediated Jun NH2- terminal kinase activation.

O53573	CYNT_MYCTU	Carbonic anhydrase	16321983	Structural mechanics of the pH-dependent activity of beta-carbonic anhydrase from Mycobacterium tuberculosis.

Q04787	BSH_DROME	Brain-specific homeobox protein	8101170	A new Drosophila homeobox gene, bsh, is expressed in a subset of brain cells during embryogenesis.

P18409	MDM10_YEAST	Mitochondrial distribution and morphology protein 10	16407407	Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins.

Q5TAX3	TUT4_HUMAN	Terminal uridylyltransferase 4	16643855	A novel Zinc finger protein, ZCCHC11, interacts with TIFA and modulates TLR signaling.

P19474	RO52_HUMAN	E3 ubiquitin-protein ligase TRIM21	16297862	Autoantigen Ro52 is an E3 ubiquitin ligase.

P33205	FXA4A_XENLA	Forkhead box protein A4-A	8367492	Ectopic neural expression of a floor plate marker in frog embryos injected with the midline transcription factor Pintallavis.

P09622	DLDH_HUMAN	Dihydrolipoyl dehydrogenase, mitochondrial	8506365	Identification of two missense mutations in a dihydrolipoamide dehydrogenase-deficient patient.

P34222	PTH2_YEAST	Peptidyl-tRNA hydrolase 2	12475929	Orthologs of a novel archaeal and of the bacterial peptidyl-tRNA hydrolase are nonessential in yeast.

Q92478	CLC2B_HUMAN	C-type lectin domain family 2 member B	9038101	AICL, a new activation induced antigen encoded by the human NK gene complex.

Q8BVN9	MAEL_MOUSE	Protein maelstrom homolog	18694567	Mouse maelstrom, a component of nuage, is essential for spermatogenesis and transposon repression in meiosis.

Q8CJ44	S13A5_RAT	Solute carrier family 13 member 5	12177002	Structure, function, and expression pattern of a novel sodium-coupled citrate transporter (NaCT) cloned from mammalian brain.

P60766	CDC42_MOUSE	Cell division control protein 42 homolog	12773384	TCGAP, a multidomain Rho GTPase-activating protein involved in insulin-stimulated glucose transport.

O13024	INCEA_XENLA	Inner centromere protein A	15260989	The chromosomal passenger complex is required for chromatin-induced microtubule stabilization and spindle assembly.

P56563	LMIP_MOUSE	Lens fiber membrane intrinsic protein	9238094	Identification of a mutation in the MP19 gene, Lim2, in the cataractous mouse mutant To3.

P53286	BTN2_YEAST	Protein BTN2	12456008	Interaction with Btn2p is required for localization of Rsglp: Btn2p- mediated changes in arginine uptake in Saccharomyces cerevisiae.

Q9M0F9	K6PF1_ARATH	6-phosphofructokinase 1	17485088	Characterisation of the ATP-dependent phosphofructokinase gene family from Arabidopsis thaliana.

P39300	ULAG_ECOLI	Probable L-ascorbate-6-phosphate lactonase ulaG	12644495	The ascorbate transporter of Escherichia coli.

P62753	RS6_HUMAN	40S ribosomal protein S6	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

P39515	TIM17_YEAST	Mitochondrial import inner membrane translocase subunit TIM17	15797382	Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17.

P0AE58	CAIF_ECOLI	Transcriptional activatory protein CaiF	8631699	Identification and characterization of the caiF gene encoding a potential transcriptional activator of carnitine metabolism in Escherichia coli.

Q8C110	SLIK6_MOUSE	SLIT and NTRK-like protein 6	14550773	Identification and characterization of Slitrk, a novel neuronal transmembrane protein family controlling neurite outgrowth.

O74349	YO89_SCHPO	Uncharacterized RING finger protein C21D10.09c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8CCH7	FOG2_MOUSE	Zinc finger protein ZFPM2	10892744	FOG-2, a cofactor for GATA transcription factors, is essential for heart morphogenesis and development of coronary vessels from epicardium.

Q9D1F4	AKTS1_MOUSE	Proline-rich AKT1 substrate 1	14973226	Neuroprotective role of a proline-rich Akt substrate in apoptotic neuronal cell death after stroke: relationships with nerve growth factor.

P08879	NDKA_DROME	Nucleoside diphosphate kinase	1320004	A Pro/Ser substitution in nucleoside diphosphate kinase of Drosophila melanogaster (mutation killer of prune) affects stability but not catalytic efficiency of the enzyme.

Q9EQ48	VN1A8_MOUSE	Vomeronasal type-1 receptor A8	11116090	Sequence diversity and genomic organization of vomeronasal receptor genes in the mouse.

Q86UE8	TLK2_HUMAN	Serine/threonine-protein kinase tousled-like 2	9427565	cDNA cloning and chromosomal mapping of genes encoding novel protein kinases termed PKU-alpha and PKU-beta, which have nuclear localization signal.

P35269	T2FA_HUMAN	General transcription factor IIF subunit 1	8625415	TAFII250 is a bipartite protein kinase that phosphorylates the base transcription factor RAP74.

P10915	HPLN1_HUMAN	Hyaluronan and proteoglycan link protein 1	2286376	Complete amino acid sequence of human cartilage link protein (CRTL1) deduced from cDNA clones and chromosomal assignment of the gene.

Q946J8	LHP1_ARATH	Chromo domain-containing protein LHP1	16361394	Different domains control the localization and mobility of LIKE HETEROCHROMATIN PROTEIN1 in Arabidopsis nuclei.

O44712	AHR_CAEEL	Aryl hydrocarbon receptor protein 1	14757639	The AHR-1 aryl hydrocarbon receptor and its co-factor the AHA-1 aryl hydrocarbon receptor nuclear translocator specify GABAergic neuron cell fate in C. elegans.

Q9H596	DUS21_HUMAN	Dual specificity protein phosphatase 21	12408986	Identification and characterization of two novel low-molecular-weight dual specificity phosphatases.

O14965	STK6_HUMAN	Serine/threonine-protein kinase 6	14580337	Structural basis of Aurora-A activation by TPX2 at the mitotic spindle.

P61092	SIA1A_MOUSE	E3 ubiquitin-protein ligase SIAH1A	16615911	Elucidation of the substrate binding site of Siah ubiquitin ligase.

O00308	WWP2_HUMAN	NEDD4-like E3 ubiquitin-protein ligase WWP2	19274063	WWP2 promotes degradation of transcription factor OCT4 in human embryonic stem cells.

Q9H4M7	PKHA4_HUMAN	Pleckstrin homology domain-containing family A member 4	11001876	Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities.

P47142	VPS25_YEAST	Vacuolar protein-sorting-associated protein 25	12194858	Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular body.

Q12004	TFB4_YEAST	RNA polymerase II transcription factor B subunit 4	10506223	The TFB4 subunit of yeast TFIIH is required for both nucleotide excision repair and RNA polymerase II transcription.

Q25619	FAR1_ONCVO	Fatty-acid and retinol-binding protein 1	12106870	The FAR proteins of filarial nematodes: secretion, glycosylation and lipid binding characteristics.

Q62651	ECH1_RAT	Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial	9417087	Delta3,5-delta2,4-dienoyl-CoA isomerase from rat liver. Molecular characterization.

Q04228	UBX2_YEAST	UBX domain-containing protein 2	14562095	Global analysis of protein localization in budding yeast.

P43427	GTR5_RAT	Solute carrier family 2, facilitated glucose transporter member 5	8333543	Sequence, tissue distribution, and functional characterization of the rat fructose transporter GLUT5.

O95218	ZRAB2_HUMAN	Zinc finger Ran-binding domain-containing protein 2	9931435	Identification, characterization and mapping of the human ZIS (zinc- finger, splicing) gene.

P17549	CP53_ASPNG	Benzoate 4-monooxygenase	11594739	Purification and characterization of benzoate-para-hydroxylase, a cytochrome P450 (CYP53A1), from Aspergillus niger.

Q9BLG4	AMT1_DICDI	Ammonium transporter 1	17951519	Regulation of ammonia homeostasis by the ammonium transporter AmtA in Dictyostelium discoideum.

O81077	ABAH2_ARATH	Abscisic acid 8'-hydroxylase 2	16543410	CYP707A1 and CYP707A2, which encode abscisic acid 8'-hydroxylases, are indispensable for proper control of seed dormancy and germination in Arabidopsis.

Q9P7Q0	YLY5_SCHPO	UPF0016 membrane protein C186.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P36896	ACV1B_HUMAN	Activin receptor type-1B	18039968	Ttrap is an essential modulator of Smad3-dependent Nodal signaling during zebrafish gastrulation and left-right axis determination.

P08541	UD2B2_RAT	UDP-glucuronosyltransferase 2B2	2429951	Rat liver UDP-glucuronosyltransferase. cDNA sequence and expression of a form glucuronidating 3-hydroxyandrogens.

P06887	LV108_HUMAN	Ig lambda chain V-I region MEM	2410269	The amino acid sequence of a lambda light chain presenting abnormal physicochemical and antigenic features.

P11182	ODB2_HUMAN	Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial	1429740	Structure of the gene encoding dihydrolipoyl transacylase (E2) component of human branched chain alpha-keto acid dehydrogenase complex and characterization of an E2 pseudogene.

Q02896	YDC1_YEAST	Alkaline ceramidase YDC1	10900202	Cloning and characterization of a Saccharomyces cerevisiae alkaline ceramidase with specificity for dihydroceramide.

P35610	SOAT1_HUMAN	Sterol O-acyltransferase 1	8407899	Molecular cloning and functional expression of human acyl-coenzyme A:cholesterol acyltransferase cDNA in mutant Chinese hamster ovary cells.

O60479	DLX3_HUMAN	Homeobox protein DLX-3	9467018	Identification of a mutation in DLX3 associated with tricho-dento- osseous (TDO) syndrome.

O60016	CLR4_SCHPO	Histone-lysine N-methyltransferase, H3 lysine-9 specific	11283354	Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly.

P40970	LCB2_YEAST	Serine palmitoyltransferase 2	8058731	The LCB2 gene of Saccharomyces and the related LCB1 gene encode subunits of serine palmitoyltransferase, the initial enzyme in sphingolipid synthesis.

P55852	SUMO1_ARATH	Small ubiquitin-related modifier 1	17644626	Genetic analysis of SUMOylation in Arabidopsis: conjugation of SUMO1 and SUMO2 to nuclear proteins is essential.

P12866	STE6_YEAST	Alpha-factor-transporting ATPase	8045256	The ABC-transporter Ste6 accumulates in the plasma membrane in a ubiquitinated form in endocytosis mutants.

Q96J01	THOC3_HUMAN	THO complex subunit 3	17190602	Human mRNA export machinery recruited to the 5' end of mRNA.

Q9NHC3	CED2_CAEEL	Cell death abnormality protein 2	1936965	Genes required for the engulfment of cell corpses during programmed cell death in Caenorhabditis elegans.

Q96QZ7	MAGI1_HUMAN	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1	9647693	Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins.

P52296	IMB1_RAT	Importin subunit beta-1	7604027	Mammalian karyopherin alpha 1 beta and alpha 2 beta heterodimers: alpha 1 or alpha 2 subunit binds nuclear localization signal and beta subunit interacts with peptide repeat-containing nucleoporins.

Q9P7N4	TAD3_SCHPO	tRNA-specific adenosine deaminase subunit tad3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8TFG7	TRM5_SCHPO	tRNA (guanine-N(1)-)-methyltransferase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q6EU39	MADS6_ORYSJ	MADS-box transcription factor 6	19820190	MOSAIC FLORAL ORGANS1, an AGL6-like MADS box gene, regulates floral organ identity and meristem fate in rice.

Q61824	ADA12_MOUSE	Disintegrin and metalloproteinase domain-containing protein 12	10788519	Binding of ADAM12, a marker of skeletal muscle regeneration, to the muscle-specific actin-binding protein, alpha-actinin-2, is required for myoblast fusion.

P40650	SX11B_XENLA	Transcription factor Sox-11-B	12047350	Involvement of NLK and Sox11 in neural induction in Xenopus development.

P30049	ATPD_HUMAN	ATP synthase subunit delta, mitochondrial	1531933	Molecular cloning of an import precursor of the delta-subunit of the human mitochondrial ATP synthase complex.

P04909	H2A1_SCHPO	Histone H2A-alpha	15226425	Histone H2A phosphorylation controls Crb2 recruitment at DNA breaks, maintains checkpoint arrest, and influences DNA repair in fission yeast.

O00590	CCBP2_HUMAN	Chemokine-binding protein 2	9364936	Cloning, expression, and chromosomal mapping of a novel human CC- chemokine receptor (CCR10) that displays high-affinity binding for MCP-1 and MCP-3.

P38820	UBA4_YEAST	Adenylyltransferase and sulfurtransferase UBA4	14562095	Global analysis of protein localization in budding yeast.

Q9LFW3	COBL4_ARATH	COBRA-like protein 4	12376623	The COBRA family of putative GPI-anchored proteins in Arabidopsis. A new fellowship in expansion.

P93655	LONM1_ARATH	Lon protease homolog 1, mitochondrial	17478548	Multiple intracellular locations of Lon protease in Arabidopsis: evidence for the localization of AtLon4 to chloroplasts.

P22389	EDN2_MOUSE	Endothelin-2	2768235	A novel peptide, vasoactive intestinal contractor, of a new (endothelin) peptide family. Molecular cloning, expression, and biological activity.

O00592	PODXL_HUMAN	Podocalyxin	18456258	Expression of podocalyxin enhances the adherence, migration, and intercellular communication of cells.

P41885	RBF1_CAEEL	Rabphilin-1	11717359	Rabphilin potentiates soluble N-ethylmaleimide sensitive factor attachment protein receptor function independently of rab3.

Q15311	RBP1_HUMAN	RalA-binding protein 1	9422736	Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of Ral.

P25446	TNR6_MOUSE	Tumor necrosis factor receptor superfamily member 6	9215629	Daxx, a novel Fas-binding protein that activates JNK and apoptosis.

P35222	CTNB1_HUMAN	Catenin beta-1	19996314	Cell-cell contact formation governs Ca2+ signaling by TRPC4 in the vascular endothelium: evidence for a regulatory TRPC4-beta-catenin interaction.

P83265	PRT2_SCOSC	Sperm protamine alpha isoform 2	9530815	Primary structure of scombrine alpha: two different species with an identical protamine.

P36632	RAD26_SCHPO	DNA repair protein rad26	12697061	Fission yeast Rad26 responds to DNA damage independently of Rad3.

P55265	DSRAD_HUMAN	Double-stranded RNA-specific adenosine deaminase	7565688	Expression and regulation by interferon of a double-stranded-RNA- specific adenosine deaminase from human cells: evidence for two forms of the deaminase.

Q64282	IFIT1_MOUSE	Interferon-induced protein with tetratricopeptide repeats 1	7896268	Structure, chromosome localization, and regulation of expression of the interferon-regulated mouse Ifi54/Ifi56 gene family.

P28715	ERCC5_HUMAN	DNA repair protein complementing XP-G cells	9305916	The DNA repair endonuclease XPG binds to proliferating cell nuclear antigen (PCNA) and shares sequence elements with the PCNA-binding regions of FEN-1 and cyclin-dependent kinase inhibitor p21.

P36969	GPX4_HUMAN	Phospholipid hydroperoxide glutathione peroxidase, mitochondrial	9705830	Structural organization of the human selenium-dependent phospholipid hydroperoxide glutathione peroxidase gene (GPX4): chromosomal localization to 19p13.3.

Q38827	IAA9_ARATH	Auxin-responsive protein IAA9	12036262	Genetics of Aux/IAA and ARF action in plant growth and development.

P32302	CXCR5_HUMAN	C-X-C chemokine receptor type 5	1425907	Differentiation-specific expression of a novel G protein-coupled receptor from Burkitt's lymphoma.

P54785	MOT3_YEAST	Transcriptional activator/repressor MOT3	12145211	Mot3 is a transcriptional repressor of ergosterol biosynthetic genes and is required for normal vacuolar function in Saccharomyces cerevisiae.

Q05043	RSF1_YEAST	Respiration factor 1	12734673	Rsf1p, a protein required for respiratory growth of Saccharomyces cerevisiae.

Q70G58	NTRC_ORYSJ	Thioredoxin reductase NTRC	16891402	Rice NTRC is a high-efficiency redox system for chloroplast protection against oxidative damage.

O43781	DYRK3_HUMAN	Dual specificity tyrosine-phosphorylation-regulated kinase 3	10779429	REDK, a novel human regulatory erythroid kinase.

Q9UR39	HST4_SCHPO	NAD-dependent deacetylase hst4	10512858	The Schizosaccharomyces pombe hst4(+) gene is a SIR2 homologue with silencing and centromeric functions.

Q9JLM9	GRB14_MOUSE	Growth factor receptor-bound protein 14	10713090	Association of fibroblast growth factor receptor 1 with the adaptor protein Grb14. Characterization of a new receptor binding partner.

Q9FQ04	XRN4_ARATH	5'-3' exoribonuclease 4	15528448	A link between mRNA turnover and RNA interference in Arabidopsis.

Q7F8U7	BURPD_ORYSJ	BURP domain-containing protein 13	14612572	The classical Ubisch bodies carry a sporophytically produced structural protein (RAFTIN) that is essential for pollen development.

Q00888	PSG4_HUMAN	Pregnancy-specific beta-1-glycoprotein 4	7794280	Characterization of cDNA encoding novel pregnancy-specific glycoprotein variants.

Q3U492	KCP_MOUSE	Kielin/chordin-like protein	15793581	Kielin/chordin-like protein, a novel enhancer of BMP signaling, attenuates renal fibrotic disease.

O01510	SMG1_CAEEL	Serine/threonine-protein kinase smg-1	2583479	A new kind of informational suppression in the nematode Caenorhabditis elegans.

P20649	PMA1_ARATH	ATPase 1, plasma membrane-type	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q22037	ROA1_CAEEL	Heterogeneous nuclear ribonucleoprotein A1	15122256	Long lifespan in worms with long telomeric DNA.

Q42599	NDUS8_ARATH	NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q9JIK1	CDHR5_RAT	Cadherin-related family member 5	10801787	mu-protocadherin, a novel developmentally regulated protocadherin with mucin-like domains.

P07379	PCKGC_RAT	Phosphoenolpyruvate carboxykinase, cytosolic [GTP]	17685635	Structures of rat cytosolic PEPCK: insight into the mechanism of phosphorylation and decarboxylation of oxaloacetic acid.

O94589	YC93_SCHPO	RanBD1 domain-containing protein C584.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Y6K9	NEMO_HUMAN	NF-kappa-B essential modulator	15620648	The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO.

O42975	YGZ5_SCHPO	UPF0614 protein C20F10.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P12839	NFM_RAT	Neurofilament medium polypeptide	1321159	Schwann cells of the myelin-forming phenotype express neurofilament protein NF-M.

Q8VDQ8	SIRT2_MOUSE	NAD-dependent deacetylase sirtuin-2	11056054	Cloning and characterization of two mouse genes with homology to the yeast sir2 gene.

P30411	BKRB2_HUMAN	B2 bradykinin receptor	18672896	Regulation of G protein-coupled receptor activities by the platelet- endothelial cell adhesion molecule, PECAM-1.

Q9VW97	LSDA_DROME	Possible lysine-specific histone demethylase 1	15306652	A conserved role but different partners for the transcriptional corepressor CoREST in fly and mammalian nervous system formation.

Q7TSJ6	LATS2_MOUSE	Serine/threonine-protein kinase LATS2	15343267	Lats2/Kpm is required for embryonic development, proliferation control and genomic integrity.

P42656	RAD24_SCHPO	DNA damage checkpoint protein rad24	12242289	The 14-3-3 proteins Rad24 and Rad25 negatively regulate Byr2 by affecting its localization in Schizosaccharomyces pombe.

Q9NZC4	EHF_HUMAN	ETS homologous factor	10644770	ESE-3, a novel member of an epithelium-specific ets transcription factor subfamily, demonstrates different target gene specificity from ESE-1.

P30086	PEBP1_HUMAN	Phosphatidylethanolamine-binding protein 1	7637590	Sequence homology of rat and human HCNP precursor proteins, bovine phosphatidylethanolamine-binding protein and rat 23-kDa protein associated with the opioid-binding protein.

Q94CD1	HHT1_ARATH	Omega-hydroxypalmitate O-feruloyl transferase	19846769	A hydroxycinnamoyltransferase responsible for synthesizing suberin aromatics in Arabidopsis.

O22151	GOS12_ARATH	Golgi SNARE 12 protein	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

Q9QZ25	VNN3_MOUSE	Vascular non-inflammatory molecule 3	11491533	Vanin genes are clustered (human 6q22-24 and mouse 10A2B1) and encode isoforms of pantetheinase ectoenzymes.

O75112	LDB3_HUMAN	LIM domain-binding protein 3	10427098	ZASP: a new Z-band alternatively spliced PDZ-motif protein.

P10834	PET54_YEAST	Protein PET54	8389363	COX3 mRNA-specific translational activator proteins are associated with the inner mitochondrial membrane in Saccharomyces cerevisiae.

Q9HBF4	ZFYV1_HUMAN	Zinc finger FYVE domain-containing protein 1	11739631	FENS-1 and DFCP1 are FYVE domain-containing proteins with distinct functions in the endosomal and Golgi compartments.

Q8VI84	NOC3L_MOUSE	Nucleolar complex protein 3 homolog	15564382	Fad24, a mammalian homolog of Noc3p, is a positive regulator in adipocyte differentiation.

P34314	TLK1_CAEEL	Serine/threonine-protein kinase tousled-like 1	15916946	The C. elegans Tousled-like kinase contributes to chromosome segregation as a substrate and regulator of the Aurora B kinase.

Q9HDV2	YHE1_SCHPO	Uncharacterized amino-acid permease PB2B2.01	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P41909	PXA1_YEAST	Peroxisomal long-chain fatty acid import protein 2	8670886	The ABC transporter proteins Pat1 and Pat2 are required for import of long-chain fatty acids into peroxisomes of Saccharomyces cerevisiae.

O13859	MU125_SCHPO	Meiotically up-regulated gene 125 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q99MD9	NASP_MOUSE	Nuclear autoantigenic sperm protein	16728391	Nuclear autoantigenic sperm protein (NASP), a linker histone chaperone that is required for cell proliferation.

P09874	PARP1_HUMAN	Poly [ADP-ribose] polymerase 1	19661379	Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1.

Q9PU13	SPD1A_XENLA	Speedy protein 1-A	16418484	Regulated Pumilio-2 binding controls RINGO/Spy mRNA translation and CPEB activation.

P53783	SOX1_MOUSE	Transcription factor SOX-1	8625802	A comparison of the properties of Sox-3 with Sry and two related genes, Sox-1 and Sox-2.

Q94KT8	COBRA_ARATH	Protein COBRA	12376623	The COBRA family of putative GPI-anchored proteins in Arabidopsis. A new fellowship in expansion.

Q9HGN6	DUS1_SCHPO	tRNA-dihydrouridine synthase 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q03735	NAB6_YEAST	RNA-binding protein NAB6	14562095	Global analysis of protein localization in budding yeast.

Q8C119	CD031_MOUSE	Fibronectin type-III domain-containing protein C4orf31 homolog	18757743	Transcriptome-based systematic identification of extracellular matrix proteins.

P43034	LIS1_HUMAN	Platelet-activating factor acetylhydrolase IB subunit alpha	9063735	Point mutations and an intragenic deletion in LIS1, the lissencephaly causative gene in isolated lissencephaly sequence and Miller-Dieker syndrome.

Q8K3F4	PP14D_RAT	Protein phosphatase 1 regulatory subunit 14D	12974676	GBPI, a novel gastrointestinal- and brain-specific PP1-inhibitory protein, is activated by PKC and inactivated by PKA.

Q91620	NOD2A_XENLA	Nodal homolog 2-A	12070085	Effects of heterodimerization and proteolytic processing on Derriere and Nodal activity: implications for mesoderm induction in Xenopus.

Q9LDF2	LAG11_ARATH	LAG1 longevity assurance homolog 1	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q9HAF1	EAF6_HUMAN	Chromatin modification-related protein MEAF6	18794358	Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexes.

Q10951	BYR4_SCHPO	Protein byr4	8682866	A novel suppressor of ras1 in fission yeast, byr4, is a dosage- dependent inhibitor of cytokinesis.

Q9P7C1	YKU3_SCHPO	Uncharacterized J domain-containing protein C2E1P5.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q26635	ATBP_SARPE	AT-rich binding protein	8307011	Purification and characterization of ATBP, a novel protein that binds to A/T stretches in three segments of the Sarcophaga lectin gene.

Q9VCR6	SAV_DROME	Scaffold protein salvador	20159598	Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded.

P30968	GNRHR_HUMAN	Gonadotropin-releasing hormone receptor	9259321	Inhibition of gonadotropin-releasing hormone receptor signaling by expression of a splice variant of the human receptor.

Q9USS2	PPK29_SCHPO	Serine/threonine-protein kinase ppk29	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P06729	CD2_HUMAN	T-cell surface antigen CD2	7544493	Conformation and function of the N-linked glycan in the adhesion domain of human CD2.

P23471	PTPRZ_HUMAN	Receptor-type tyrosine-protein phosphatase zeta	8387522	The cloning of a receptor-type protein tyrosine phosphatase expressed in the central nervous system.

Q8IYX4	DND1_HUMAN	Dead end protein homolog 1	18155131	RNA-binding protein Dnd1 inhibits microRNA access to target mRNA.

O14012	RRP17_SCHPO	Ribosomal RNA-processing protein 17	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P62168	NCS1_RAT	Neuronal calcium sensor 1	17502602	IL1-receptor accessory protein-like 1 (IL1RAPL1), a protein involved in cognitive functions, regulates N-type Ca2+-channel and neurite elongation.

Q8R5M3	LRC15_RAT	Leucine-rich repeat-containing protein 15	11785964	A novel member of the leucine-rich repeat superfamily induced in rat astrocytes by beta-amyloid.

Q99714	HCD2_HUMAN	3-hydroxyacyl-CoA dehydrogenase type-2	18984158	RNase P without RNA: identification and functional reconstitution of the human mitochondrial tRNA processing enzyme.

O22126	FLA8_ARATH	Fasciclin-like arabinogalactan protein 8	12805588	Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis.

Q90YM8	CYFP1_DANRE	Cytoplasmic FMR1-interacting protein 1 homolog	11438699	A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P.

Q8N5K1	CISD2_HUMAN	CDGSH iron-sulfur domain-containing protein 2	20010695	Antagonism of Beclin 1-dependent autophagy by BCL-2 at the endoplasmic reticulum requires NAF-1.

P36016	LHS1_YEAST	Heat shock protein 70 homolog LHS1	8654361	A novel Hsp70 of the yeast ER lumen is required for the efficient translocation of a number of protein precursors.

P53814	SMTN_HUMAN	Smoothelin	8707825	Smoothelin, a novel cytoskeletal protein specific for smooth muscle cells.

Q9QZZ6	DERM_MOUSE	Dermatopontin	12230512	Targeted disruption of dermatopontin causes abnormal collagen fibrillogenesis.

Q19849	EGL44_CAEEL	Transcription enhancer factor-like protein egl-44	11274062	Inhibition of touch cell fate by egl-44 and egl-46 in C. elegans.

O54904	B3GT1_MOUSE	Beta-1,3-galactosyltransferase 1	9417047	Genomic cloning and expression of three murine UDP-galactose: beta-N- acetylglucosamine beta1,3-galactosyltransferase genes.

P05362	ICAM1_HUMAN	Intercellular adhesion molecule 1	3349522	Primary structure of ICAM-1 demonstrates interaction between members of the immunoglobulin and integrin supergene families.

Q03305	RMT2_YEAST	Arginine N-methyltransferase 2	14562095	Global analysis of protein localization in budding yeast.

P35240	MERL_HUMAN	Merlin	9430655	NHE-RF, a regulatory cofactor for Na(+)-H+ exchange, is a common interactor for merlin and ERM (MERM) proteins.

Q02642	NACB1_YEAST	Nascent polypeptide-associated complex subunit beta-1	10219998	Initial characterization of the nascent polypeptide-associated complex in yeast.

Q29983	MICA_HUMAN	MHC class I polypeptide-related sequence A	16750166	Down-regulation of the NKG2D ligand MICA by the human cytomegalovirus glycoprotein UL142.

Q8NHJ6	LIRB4_HUMAN	Leukocyte immunoglobulin-like receptor subfamily B member 4	9548455	A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules.

Q792I0	LIN7C_RAT	Protein lin-7 homolog C	15024025	Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins.

Q16531	DDB1_HUMAN	DNA damage-binding protein 1	11673459	UV-damaged DNA-binding proteins are targets of CUL-4A-mediated ubiquitination and degradation.

P83939	SCRN1_BOVIN	Secernin-1	12221138	Purification and identification of secernin, a novel cytosolic protein that regulates exocytosis in mast cells.

Q05040	FAR8_YEAST	Factor arrest protein 8	12588993	Far3 and five interacting proteins prevent premature recovery from pheromone arrest in the budding yeast Saccharomyces cerevisiae.

P56705	WNT4_HUMAN	Protein Wnt-4	16959810	WNT4 deficiency-a clinical phenotype distinct from the classic Mayer- Rokitansky-Kuster-Hauser syndrome: a case report.

Q14643	ITPR1_HUMAN	Inositol 1,4,5-trisphosphate receptor type 1	7500840	Molecular cloning of a cDNA for the human inositol 1,4,5- trisphosphate receptor type 1, and the identification of a third alternatively spliced variant.

O82660	P2SAF_ARATH	Photosystem II stability/assembly factor HCF136, chloroplastic	12459468	The HCF136 protein is essential for assembly of the photosystem II reaction center in Arabidopsis thaliana.

O00237	RN103_HUMAN	E3 ubiquitin-protein ligase RNF103	9070305	Cloning of human and mouse cDNAs encoding novel zinc finger proteins expressed in cerebellum and hippocampus.

Q9FN42	CLPP2_ARATH	ATP-dependent Clp protease proteolytic subunit 2, mitochondrial	11278690	Identification of a 350-kDa ClpP protease complex with 10 different Clp isoforms in chloroplasts of Arabidopsis thaliana.

P47069	MPS3_YEAST	Spindle pole body assembly component MPS3	15355977	The spindle pole body assembly component Mps3p/Nep98p functions in sister chromatid cohesion.

Q9VI75	PICA_DROME	Phosphatidylinositol-binding clathrin assembly protein LAP	9883738	Synaptic vesicle size and number are regulated by a clathrin adaptor protein required for endocytosis.

Q9Y6M1	IF2B2_HUMAN	Insulin-like growth factor 2 mRNA-binding protein 2	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

Q43127	GLNA2_ARATH	Glutamine synthetase, chloroplastic/mitochondrial	15273293	Arabidopsis thaliana GLN2-encoded glutamine synthetase is dual targeted to leaf mitochondria and chloroplasts.

P15514	AREG_HUMAN	Amphiregulin	2466334	Structure and function of human amphiregulin: a member of the epidermal growth factor family.

Q09517	LE767_CAEEL	Putative steroid dehydrogenase let-767	12905072	The sterol modifying enzyme LET-767 is essential for growth, reproduction and development in Caenorhabditis elegans.

Q39204	RAP1_ARATH	Transcription factor MYC2	9368419	Role of Arabidopsis MYC and MYB homologs in drought- and abscisic acid-regulated gene expression.

P53241	VHT1_YEAST	Vitamin H transporter	10373489	Identification of the plasma membrane H+-biotin symporter of Saccharomyces cerevisiae by rescue of a fatty acid-auxotrophic mutant.

P78344	IF4G2_HUMAN	Eukaryotic translation initiation factor 4 gamma 2	9049310	A new translational regulator with homology to eukaryotic translation initiation factor 4G.

Q07258	TGFB3_RAT	Transforming growth factor beta-3	7852342	Cloning and expression of glucocorticoid-induced genes in fetal rat lung fibroblasts. Transforming growth factor-beta 3.

Q94IN5	PNO_EUGGR	Pyruvate dehydrogenase [NADP+], mitochondrial	12623066	Pyruvate:NADP(+) oxidoreductase is stabilized by its cofactor, thiamin pyrophosphate, in mitochondria of Euglena gracilis.

P77398	ARNA_ECOLI	Bifunctional polymyxin resistance protein ArnA	15491143	Crystal structure of Escherichia coli ArnA (PmrI) decarboxylase domain. A key enzyme for lipid A modification with 4-amino-4-deoxy-L- arabinose and polymyxin resistance.

P32457	CDC3_YEAST	Cell division control protein 3	12665577	Molecular dissection of a yeast septin: distinct domains are required for septin interaction, localization, and function.

Q8VDD8	WASH1_MOUSE	WAS protein family homolog 1	19922875	The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex.

Q9VAW5	LARP_DROME	La-related protein	14668392	Green fluorescent protein tagging Drosophila proteins at their native genomic loci with small P elements.

Q13017	RHG05_HUMAN	Rho GTPase-activating protein 5	8537347	p190-B, a new member of the Rho GAP family, and Rho are induced to cluster after integrin cross-linking.

O59697	PPK25_SCHPO	Serine/threonine-protein kinase ppk25	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P32897	TIM23_YEAST	Mitochondrial import inner membrane translocase subunit TIM23	10830167	Tim23 links the inner and outer mitochondrial membranes.

P47002	SSY5_YEAST	SPS-sensor serine protease component SSY5	16524914	Mapping of an internal protease cleavage site in the Ssy5p component of the amino acid sensor of Saccharomyces cerevisiae and functional characterization of the resulting pro- and protease domains by gain- of-function genetics.

P97943	SCRB1_RAT	Scavenger receptor class B member 1	12016218	Phosphatidylserine binding of class B scavenger receptor type I, a phagocytosis receptor of testicular Sertoli cells.

P47974	TISD_HUMAN	Zinc finger protein 36, C3H1 type-like 2	7835719	ERF-2, the human homologue of the murine Tis11d early response gene.

Q13387	JIP2_HUMAN	C-Jun-amino-terminal kinase-interacting protein 2	10490659	The JIP group of mitogen-activated protein kinase scaffold proteins.

Q9FG67	MAM1_ARATH	Methylthioalkylmalate synthase 1, chloroplastic	14740211	Biosynthesis of methionine-derived glucosinolates in Arabidopsis thaliana: recombinant expression and characterization of methylthioalkylmalate synthase, the condensing enzyme of the chain- elongation cycle.

Q09690	POM1_SCHPO	Dual specificity protein kinase pom1	9573052	Pom1p, a fission yeast protein kinase that provides positional information for both polarized growth and cytokinesis.

P14681	KSS1_YEAST	Mitogen-activated protein kinase KSS1	9744865	Repression of yeast Ste12 transcription factor by direct binding of unphosphorylated Kss1 MAPK and its regulation by the Ste7 MEK.

A2AAY5	SPD2B_MOUSE	SH3 and PX domain-containing protein 2B	18959745	A novel gene, fad49, plays a crucial role in the immediate early stage of adipocyte differentiation via involvement in mitotic clonal expansion.

Q9V431	API5_DROME	Apoptosis inhibitor 5 homolog	17112319	Functional identification of Api5 as a suppressor of E2F-dependent apoptosis in vivo.

Q99958	FOXC2_HUMAN	Forkhead box protein C2	9169153	Isolation of the mouse (MFH-1) and human (FKHL 14) mesenchyme fork head-1 genes reveals conservation of their gene and protein structures.

Q38874	STM_ARATH	Homeobox protein SHOOT MERISTEMLESS	16513846	Nuclear import of the transcription factor SHOOT MERISTEMLESS depends on heterodimerization with BLH proteins expressed in discrete sub- domains of the shoot apical meristem of Arabidopsis thaliana.

Q9VT51	INSL2_DROME	Probable insulin-like peptide 2	11250149	An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control.

Q9H2M9	RBGPR_HUMAN	Rab3 GTPase-activating protein non-catalytic subunit	9733780	Molecular cloning and characterization of the noncatalytic subunit of the Rab3 subfamily-specific GTPase-activating protein.

P53276	UTP8_YEAST	U3 small nucleolar RNA-associated protein 8	12794079	Utp8p is an essential intranuclear component of the nuclear tRNA export machinery of Saccharomyces cerevisiae.

Q8LB02	DHSB2_ARATH	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit 2, mitochondrial	11442063	Three different genes encode the iron-sulphur subunit of succinate dehydrogenase in Arabidopsis thaliana.

Q15628	TRADD_HUMAN	Tumor necrosis factor receptor type 1-associated DEATH domain protein	11684708	Keratin attenuates tumor necrosis factor-induced cytotoxicity through association with TRADD.

Q9SKT0	THF1_ARATH	Protein THYLAKOID FORMATION 1, chloroplastic	15516501	Deletion of the chloroplast-localized thylakoid formation1 gene product in Arabidopsis leads to deficient thylakoid formation and variegated leaves.

P70610	DOC2B_RAT	Double C2-like domain-containing protein beta	18596155	DOC2B acts as a calcium switch and enhances vesicle fusion.

Q9Y672	ALG6_HUMAN	Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase	10359825	A mutation in the human ortholog of the Saccharomyces cerevisiae ALG6 gene causes carbohydrate-deficient glycoprotein syndrome type-Ic.

O94486	CHR2_SCHPO	Chitin synthase regulatory factor 2	15449309	Chr4, a Schizosaccharomyces pombe homologue of the Saccharomyces cerevisiae Chs4p/Skt5p protein, is related to septum formation and is required for the proper localization of Chs2.

P32266	MGM1_YEAST	Dynamin-like GTPase MGM1, mitochondrial	1532158	Mitochondrial DNA maintenance in yeast requires a protein containing a region related to the GTP-binding domain of dynamin.

O49048	VPS45_ARATH	Vacuolar protein sorting-associated protein 45 homolog	9625693	An Arabidopsis VPS45p homolog implicated in protein transport to the vacuole.

Q15428	SF3A2_HUMAN	Splicing factor 3A subunit 2	8211113	Correspondence between a mammalian spliceosome component and an essential yeast splicing factor.

Q9UER7	DAXX_HUMAN	Death domain-associated protein 6	10669754	Sequestration and inhibition of Daxx-mediated transcriptional repression by PML.

Q9NYV6	RRN3_HUMAN	RNA polymerase I-specific transcription initiation factor RRN3	12393749	Multiple interactions between RNA polymerase I, TIF-IA and TAF(I) subunits regulate preinitiation complex assembly at the ribosomal gene promoter.

Q9Y2C3	B3GT5_HUMAN	Beta-1,3-galactosyltransferase 5	10212226	Cloning, expression, and characterization of a novel UDP- galactose:beta-N-acetylglucosamine beta1,3-galactosyltransferase (beta3Gal-T5) responsible for synthesis of type 1 chain in colorectal and pancreatic epithelia and tumor cells derived therefrom.

Q99K67	AASS_MOUSE	Alpha-aminoadipic semialdehyde synthase, mitochondrial	10567240	Lysine degradation through the saccharopine pathway in mammals: involvement of both bifunctional and monofunctional lysine-degrading enzymes in mouse.

P53566	CEBPA_MOUSE	CCAAT/enhancer-binding protein alpha	19641492	Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-beta transcriptional complex.

P25651	CSM1_YEAST	Monopolin complex subunit CSM1	11470404	A screen for genes required for meiosis and spore formation based on whole-genome expression.

P10896	RCA_ARATH	Ribulose bisphosphate carboxylase/oxygenase activase, chloroplastic	16461379	Protein profiling of plastoglobules in chloroplasts and chromoplasts. A surprising site for differential accumulation of metabolic enzymes.

P23467	PTPRB_HUMAN	Receptor-type tyrosine-protein phosphatase beta	19136612	Transcriptional profiling reveals a critical role for tyrosine phosphatase VE-PTP in regulation of VEGFR2 activity and endothelial cell morphogenesis.

O74791	GRN1_SCHPO	GTPase grn1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P83222	NUC34_STRAT	34 kDa extracellular nuclease	10400660	Purification, characterization, and role of nucleases and serine proteases in Streptomyces differentiation. Analogies with the biochemical processes described in late steps of eukaryotic apoptosis.

P80428	ARP4_YEAST	Actin-related protein 4	14690608	A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1.

P61981	1433G_HUMAN	14-3-3 protein gamma	10433554	14-3-3gamma interacts with and is phosphorylated by multiple protein kinase C isoforms in PDGF-stimulated human vascular smooth muscle cells.

B1AXD8	AKIR2_MOUSE	Akirin-2	18066067	Akirins are highly conserved nuclear proteins required for NF-kappaB- dependent gene expression in Drosophila and mice.

Q99594	TEAD3_HUMAN	Transcriptional enhancer factor TEF-5	18579750	TEAD mediates YAP-dependent gene induction and growth control.

Q12468	CSN5_YEAST	COP9 signalosome complex subunit 5	12183637	Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1.

Q9ZVJ6	ANXD4_ARATH	Annexin D4	15161963	Proteomic identification of annexins, calcium-dependent membrane binding proteins that mediate osmotic stress and abscisic acid signal transduction in Arabidopsis.

P40426	PBX3_HUMAN	Pre-B-cell leukemia transcription factor 3	1682799	PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1.

Q24434	ORD_DROME	Protein ORD	14669021	A proposed role for the Polycomb group protein dRING in meiotic sister-chromatid cohesion.

P84194	GUNA_GLOTR	Endoglucanase Cel5A	15870328	Processive endoglucanase active in crystalline cellulose hydrolysis by the brown rot basidiomycete Gloeophyllum trabeum.

P25870	CLH_DICDI	Clathrin heavy chain	9425628	Purification of clathrin heavy and light chain from Dictyostelium discoideum.

Q27934	PHYL_DROME	Protein phyllopod	7859287	Control of Drosophila photoreceptor cell fates by phyllopod, a novel nuclear protein acting downstream of the Raf kinase.

P49765	VEGFB_HUMAN	Vascular endothelial growth factor B	8637916	Vascular endothelial growth factor B, a novel growth factor for endothelial cells.

Q2A865	S6A19_RAT	Sodium-dependent neutral amino acid transporter B(0)AT1	17264310	High-salt intake and the renal expression of amino acid transporters in spontaneously hypertensive rats.

P0ACU2	RUTR_ECOLI	HTH-type transcriptional regulator rutR	16540542	A previously undescribed pathway for pyrimidine catabolism.

O54937	PDK4_RAT	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial	9405293	Evidence for existence of tissue-specific regulation of the mammalian pyruvate dehydrogenase complex.

Q9NZD8	SPG21_HUMAN	Maspardin	11113139	Cloning of ACP33 as a novel intracellular ligand of CD4.

Q05471	SWR1_YEAST	Helicase SWR1	14645854	ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex.

Q92325	LAG2_YEAST	Longevity-assurance protein 2	8760941	LAG2, a gene that determines yeast longevity.

P51553	IDH3G_HUMAN	Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial	11256614	Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.

O60663	LMX1B_HUMAN	LIM homeobox transcription factor 1-beta	9618165	Loss-of-function mutations in the LIM-homeodomain gene, LMX1B, in nail-patella syndrome.

Q7F1M0	KU70_ORYSJ	ATP-dependent DNA helicase 2 subunit KU70	19923234	OsKu70 is associated with developmental growth and genome stability in rice.

P50895	BCAM_HUMAN	Basal cell adhesion molecule	9166867	Use of domain-deletion mutants to locate Lutheran blood group antigens to each of the five immunoglobulin superfamily domains of the Lutheran glycoprotein: elucidation of the molecular basis of the Lu(a)/Lu(b) and the Au(a)/Au(b) polymorphisms.

Q7SYN5	RXRBA_DANRE	Retinoic acid receptor RXR-beta-A	7565671	New retinoid X receptor subtypes in zebra fish (Danio rerio) differentially modulate transcription and do not bind 9-cis retinoic acid.

Q16568	CART_HUMAN	Cocaine- and amphetamine-regulated transcript protein	11478874	Solution structure of the satiety factor, CART, reveals new functionality of a well-known fold.

Q8CEE0	CEP57_MOUSE	Centrosomal protein of 57 kDa	18294141	Cep57, a multidomain protein with unique microtubule and centrosomal localization domains.

P28817	HIBCH_YEAST	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Q93070	NAR4_HUMAN	Ecto-ADP-ribosyltransferase 4	11001920	Identification of the Dombrock blood group glycoprotein as a polymorphic member of the ADP-ribosyltransferase gene family.

Q7TNF0	DOC2A_MOUSE	Double C2-like domain-containing protein alpha	18354201	Doc2 alpha and Munc13-4 regulate Ca(2+) -dependent secretory lysosome exocytosis in mast cells.

Q9W1N5	GR59F_DROME	Putative gustatory receptor 59f	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

P38696	ARP1_YEAST	Centractin	9658168	The yeast dynactin complex is involved in partitioning the mitotic spindle between mother and daughter cells during anaphase B.

Q96RK4	BBS4_HUMAN	Bardet-Biedl syndrome 4 protein	15107855	The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression.

Q20497	MED12_CAEEL	Mediator of RNA polymerase II transcription subunit 12	12441291	A component of the transcriptional mediator complex inhibits RAS- dependent vulval fate specification in C. elegans.

P12109	CO6A1_HUMAN	Collagen alpha-1(VI) chain	2551668	Sequence analysis of alpha 1(VI) and alpha 2(VI) chains of human type VI collagen reveals internal triplication of globular domains similar to the A domains of von Willebrand factor and two alpha 2(VI) chain variants that differ in the carboxy terminus.

Q16531	DDB1_HUMAN	DNA damage-binding protein 1	18593899	The cullin 4B-based UV-damaged DNA-binding protein ligase binds to UV-damaged chromatin and ubiquitinates histone H2A.

Q9C2Z0	PLYA_ASPNG	Pectate lyase A	11112543	Characterization of Aspergillus niger pectate lyase A.

Q14469	HES1_HUMAN	Transcription factor HES-1	8020957	Genomic cloning and chromosomal localization of HRY, the human homolog to the Drosophila segmentation gene, hairy.

Q09994	ANI2_CAEEL	Anillin-like protein 2	15930113	Distinct roles for two C. elegans anillins in the gonad and early embryo.

Q9HCH5	SYTL2_HUMAN	Synaptotagmin-like protein 2	18812475	A newly identified isoform of Slp2a associates with Rab27a in cytotoxic T cells and participates to cytotoxic granule secretion.

Q7ZYQ0	FXI1E_XENLA	Forkhead box protein I1-ema	15901660	Xema, a foxi-class gene expressed in the gastrula stage Xenopus ectoderm, is required for the suppression of mesendoderm.

P30575	ENO1_CANAL	Enolase 1	1400228	Molecular cloning of cDNA and analysis of protein secondary structure of Candida albicans enolase, an abundant, immunodominant glycolytic enzyme.

P11632	NHP6A_YEAST	Non-histone chromosomal protein 6A	11239460	Nhp6, an HMG1 protein, functions in SNR6 transcription by RNA polymerase III in S. cerevisiae.

P53129	MON1_YEAST	Vacuolar fusion protein MON1	12387888	Yeast Mon1p/Aut12p functions in vacuolar fusion of autophagosomes and cvt-vesicles.

P26321	RL5_YEAST	60S ribosomal protein L5	8474444	Yeast ribosomal protein L1 is required for the stability of newly synthesized 5S rRNA and the assembly of 60S ribosomal subunits.

Q9NTI5	PDS5B_HUMAN	Sister chromatid cohesion protein PDS5 homolog B	10963680	Androgen-induced proliferative quiescence in prostate cancer cells: the role of AS3 as its mediator.

Q9VUN3	RANL_DROME	GTP-binding nuclear protein Ran-like	12653959	Tamo selectively modulates nuclear import in Drosophila.

O14813	PHX2A_HUMAN	Paired mesoderm homeobox protein 2A	8661014	Mapping of the ARIX homeodomain gene to mouse chromosome 7 and human chromosome 11q13.

Q7Z7M9	GALT5_HUMAN	Polypeptide N-acetylgalactosaminyltransferase 5	10545594	A direct interaction between EXT proteins and glycosyltransferases is defective in hereditary multiple exostoses.

Q9Y2L8	ZKSC5_HUMAN	Zinc finger protein with KRAB and SCAN domains 5	10585779	Isolation, characterization, and mapping of a zinc finger gene, ZFP95, containing both a SCAN box and an alternatively spliced KRAB A domain.

Q23356	MIG15_CAEEL	Serine/threonine-protein kinase mig-15	11967148	A conserved interaction between beta1 integrin/PAT-3 and Nck- interacting kinase/MIG-15 that mediates commissural axon navigation in C. elegans.

Q8N4A0	GALT4_HUMAN	Polypeptide N-acetylgalactosaminyltransferase 4	9804815	Cloning of a human UDP-N-acetyl-alpha-D-Galactosamine:polypeptide N- acetylgalactosaminyltransferase that complements other GalNAc- transferases in complete O-glycosylation of the MUC1 tandem repeat.

Q54NP6	SNAA_DICDI	Alpha-soluble NSF attachment protein	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q5FYB0	ARSJ_HUMAN	Arylsulfatase J	16174644	Sulfatases and sulfatase modifying factors: an exclusive and promiscuous relationship.

Q9W4Y2	PDFR_DROME	PDF receptor	16242403	A G protein-coupled receptor, groom-of-PDF, is required for PDF neuron action in circadian behavior.

P17302	CXA1_HUMAN	Gap junction alpha-1 protein	7715640	Mutations of the connexin43 gap-junction gene in patients with heart malformations and defects of laterality.

Q9HE02	SSN2_SCHPO	Mediator of RNA polymerase II transcription subunit 13	12738880	TRAP230/ARC240 and TRAP240/ARC250 Mediator subunits are functionally conserved through evolution.

P41821	MID1_YEAST	Stretch-activated cation channel MID1	10958666	A homolog of voltage-gated Ca(2+) channels stimulated by depletion of secretory Ca(2+) in yeast.

Q54E04	VATM_DICDI	Vacuolar proton translocating ATPase 100 kDa subunit	8743951	The vacuolar proton pump of Dictyostelium discoideum: molecular cloning and analysis of the 100 kDa subunit.

O13633	YNF5_SCHPO	Uncharacterized J domain-containing protein C17A3.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9D6J4	NECA3_MOUSE	N-terminal EF-hand calcium-binding protein 3	10833507	Regulation of X11L-dependent amyloid precursor protein metabolism by XB51, a novel X11L-binding protein.

Q6UWZ7	F175A_HUMAN	BRCA1-A complex subunit Abraxas	19261746	MERIT40 controls BRCA1-Rap80 complex integrity and recruitment to DNA double-strand breaks.

Q7RTV3	ZN367_HUMAN	Zinc finger protein 367	15344908	Molecular cloning and characterization of ZFF29: a protein containing a unique Cys2His2 zinc-finger motif.

P35669	GSHB_SCHPO	Glutathione synthetase large chain	10219997	Biosynthesis of phytochelatins in the fission yeast. Phytochelatin synthesis: a second role for the glutathione synthetase gene of Schizosaccharomyces pombe.

P97479	MYO7A_MOUSE	Myosin-VIIa	15590698	Myosin XVa and whirlin, two deafness gene products required for hair bundle growth, are located at the stereocilia tips and interact directly.

Q9H2F5	EPC1_HUMAN	Enhancer of polycomb homolog 1	10976108	RET finger protein is a transcriptional repressor and interacts with enhancer of polycomb that has dual transcriptional functions.

P57752	ACBP6_ARATH	Acyl-CoA-binding domain-containing protein 6	18621979	Overexpression of the Arabidopsis 10-kilodalton acyl-coenzyme A- binding protein ACBP6 enhances freezing tolerance.

O22870	FKBP2_ARATH	Probable FKBP-type peptidyl-prolyl cis-trans isomerase 2, chloroplastic	11719511	Proteome map of the chloroplast lumen of Arabidopsis thaliana.

P09007	SRD1_YEAST	Pre-rRNA-processing protein SRD1	2179050	SRD1, a Saccharomyces cerevisiae suppressor of the temperature- sensitive pre-rRNA processing defect of rrp1-1.

P17655	CAN2_HUMAN	Calpain-2 catalytic subunit	10639123	The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium.

Q12373	HIF1_YEAST	HAT1-interacting factor 1	15099519	The nuclear Hat1p/Hat2p complex: a molecular link between type B histone acetyltransferases and chromatin assembly.

Q15544	TAF11_HUMAN	Transcription initiation factor TFIID subunit 11	7729427	Cloning and characterization of hTAFII18, hTAFII20 and hTAFII28: three subunits of the human transcription factor TFIID.

Q8LBA6	PIS1_ARATH	CDP-diacylglycerol--inositol 3-phosphatidyltransferase 1	10411624	Identification of AtPIS, a phosphatidylinositol synthase from Arabidopsis.

P40514	YIG7_YEAST	Uncharacterized protein YIL067C	14562095	Global analysis of protein localization in budding yeast.

P49862	KLK7_HUMAN	Kallikrein-7	8034709	Cloning, expression, and characterization of stratum corneum chymotryptic enzyme. A skin-specific human serine proteinase.

Q15349	KS6A2_HUMAN	Ribosomal protein S6 kinase alpha-2	7623830	RSK3 encodes a novel pp90rsk isoform with a unique N-terminal sequence: growth factor-stimulated kinase function and nuclear translocation.

Q61335	BAP31_MOUSE	B-cell receptor-associated protein 31	8612576	The specificity of association of the IgD molecule with the accessory proteins BAP31/BAP29 lies in the IgD transmembrane sequence.

P32738	CLAT_RAT	Choline O-acetyltransferase	15477102	Structural insights and functional implications of choline acetyltransferase.

P89102	SEC5_YEAST	Exocyst complex component SEC5	8978675	The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae.

O14763	TR10B_HUMAN	Tumor necrosis factor receptor superfamily member 10B	9430227	Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway.

Q99828	CIB1_HUMAN	Calcium and integrin-binding protein 1	15685448	G1P3, an interferon inducible gene 6-16, is expressed in gastric cancers and inhibits mitochondrial-mediated apoptosis in gastric cancer cell line TMK-1 cell.

Q6VYH9	HSH2D_MOUSE	Hematopoietic SH2 domain-containing protein	12960172	Cloning and characterization of ALX, an adaptor downstream of CD28.

Q99KJ8	DCTN2_MOUSE	Dynactin subunit 2	11483508	Mammalian Golgi-associated Bicaudal-D2 functions in the dynein- dynactin pathway by interacting with these complexes.

Q03924	ZN117_HUMAN	Zinc finger protein 117	2023909	The evolutionarily conserved Kruppel-associated box domain defines a subfamily of eukaryotic multifingered proteins.

Q9BWT1	CDCA7_HUMAN	Cell division cycle-associated protein 7	11598121	A novel c-Myc-responsive gene, JPO1, participates in neoplastic transformation.

O95155	UBE4B_HUMAN	Ubiquitin conjugation factor E4 B	11802788	The human homologue of the yeast polyubiquitination factor Ufd2p is cleaved by caspase 6 and granzyme B during apoptosis.

O95977	S1PR4_HUMAN	Sphingosine 1-phosphate receptor 4	9790765	EDG6, a novel G protein-coupled receptor related to receptors for bioactive lysophospholipids, is specifically expressed in lymphoid tissue.

Q9FUJ2	CKX4_ARATH	Cytokinin dehydrogenase 4	14555694	Cytokinin-deficient transgenic Arabidopsis plants show multiple developmental alterations indicating opposite functions of cytokinins in the regulation of shoot and root meristem activity.

Q99KV1	DJB11_MOUSE	DnaJ homolog subfamily B member 11	11584023	A DnaJ protein, apobec-1-binding protein-2, modulates apolipoprotein B mRNA editing.

O14467	MBF1_YEAST	Multiprotein-bridging factor 1	9710580	Yeast coactivator MBF1 mediates GCN4-dependent transcriptional activation.

P41800	MMM1_YEAST	Maintenance of mitochondrial morphology protein 1	8089172	MMM1 encodes a mitochondrial outer membrane protein essential for establishing and maintaining the structure of yeast mitochondria.

Q8NI77	KI18A_HUMAN	Kinesin-like protein KIF18A	17006958	MS-KIF18A, a kinesin, is associated with estrogen receptor.

O88553	ZFP37_RAT	Zinc finger protein 37	9772206	Identification of a novel peroxisome proliferator responsive cDNA isolated from rat hepatocytes as the zinc-finger protein ZFP-37.

P63005	LIS1_MOUSE	Platelet-activating factor acetylhydrolase IB subunit alpha	12796778	14-3-3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome.

Q80UG2	PLXA4_MOUSE	Plexin-A4	12591607	Identification and characterization of a novel mouse plexin, plexin- A4.

Q13362	2A5G_HUMAN	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform	16580887	PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation.

Q39026	MPK6_ARATH	Mitogen-activated protein kinase 6	11577197	Oxidative stress activates ATMPK6, an Arabidopsis homologue of MAP kinase.

Q13618	CUL3_HUMAN	Cullin-3	8681378	cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family.

P07884	MOD5_YEAST	tRNA dimethylallyltransferase, mitochondrial	18852462	Crystallographic snapshots of eukaryotic dimethylallyltransferase acting on tRNA: insight into tRNA recognition and reaction mechanism.

Q8L8Q7	COBL2_ARATH	COBRA-like protein 2	14517339	Proteomic analysis of glycosylphosphatidylinositol-anchored membrane proteins.

Q09892	HOG1_SCHPO	Mitogen-activated protein kinase sty1	15870269	Response of fission yeast to toxic cations involves cooperative action of the stress-activated protein kinase Spc1/Sty1 and the Hal4 protein kinase.

Q00839	HNRPU_HUMAN	Heterogeneous nuclear ribonucleoprotein U	1628625	Primary structure and binding activity of the hnRNP U protein: binding RNA through RGG box.

Q14587	ZN268_HUMAN	Zinc finger protein 268	11311945	Cloning and characterization of a novel Kruppel-like zinc finger gene, ZNF268, expressed in early human embryo.

O95273	CCDB1_HUMAN	Cyclin-D1-binding protein 1	10915743	Human homologue of maid: a dominant inhibitory helix-loop-helix protein associated with liver-specific gene expression.

Q9R0M4	PODXL_MOUSE	Podocalyxin	17311105	The CD34-related molecule podocalyxin is a potent inducer of microvillus formation.

O43292	GPAA1_HUMAN	Glycosylphosphatidylinositol anchor attachment 1 protein	11483512	PIG-S and PIG-T, essential for GPI anchor attachment to proteins, form a complex with GAA1 and GPI8.

Q95YE9	CLK2_CAEEL	Telomere length regulation protein clk-2	11696330	C. elegans clk-2, a gene that limits life span, encodes a telomere length regulator similar to yeast telomere binding protein Tel2p.

Q9Y2R5	RT17_HUMAN	28S ribosomal protein S17, mitochondrial	11279123	The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present.

P18899	DDR48_YEAST	Stress protein DDR48	2111448	Structure of the DNA damage-inducible gene DDR48 and evidence for its role in mutagenesis in Saccharomyces cerevisiae.

Q63625	PHRF1_RAT	PHD and RING finger domain-containing protein 1	8692929	The C-terminal domain of the largest subunit of RNA polymerase II interacts with a novel set of serine/arginine-rich proteins.

Q08649	ESA1_YEAST	Histone acetyltransferase ESA1	12353039	Acetylation of histone H4 by Esa1 is required for DNA double-strand break repair.

Q9SND4	HEC2_ARATH	Transcription factor HEC2	17855426	The HECATE genes regulate female reproductive tract development in Arabidopsis thaliana.

Q17551	RPM1_CAEEL	E3 ubiquitin-protein ligase rpm-1	15707898	Regulation of a DLK-1 and p38 MAP kinase pathway by the ubiquitin ligase RPM-1 is required for presynaptic development.

P35355	PGH2_RAT	Prostaglandin G/H synthase 2	8203528	Cloning and characterization of a growth factor-inducible cyclooxygenase gene from rat intestinal epithelial cells.

Q9V4S8	CSN7_DROME	COP9 signalosome complex subunit 7	12737805	The COP9 signalosome promotes degradation of Cyclin E during early Drosophila oogenesis.

Q01081	U2AF1_HUMAN	Splicing factor U2AF 35 kDa subunit	11551507	A novel peptide recognition mode revealed by the X-ray structure of a core U2AF35/U2AF65 heterodimer.

Q05546	TENR_RAT	Tenascin-R	15296743	Structural basis for interactions between tenascins and lectican C- type lectin domains: evidence for a crosslinking role for tenascins.

P30153	2AAA_HUMAN	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform	16580887	PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation.

P0A6N4	EFP_ECOLI	Elongation factor P	18201202	Interactions of elongation factor EF-P with the Escherichia coli ribosome.

P27918	PROP_HUMAN	Properdin	8530058	Sequence-based analysis of properdin deficiency: identification of point mutations in two phenotypic forms of an X-linked immunodeficiency.

Q07824	TPO1_YEAST	Polyamine transporter 1	15637075	Characteristics of the polyamine transporter TPO1 and regulation of its activity and cellular localization by phosphorylation.

P83564	GPX1_CHLRE	Glutathione peroxidase 1, mitochondrial	11973339	A selenoprotein in the plant kingdom. Mass spectrometry confirms that an opal codon (UGA) encodes selenocysteine in Chlamydomonas reinhardtii glutathione peroxidase.

P04637	P53_HUMAN	Cellular tumor antigen p53	17245430	A specific PP2A regulatory subunit, B56gamma, mediates DNA damage- induced dephosphorylation of p53 at Thr55.

P20965	PABPA_XENLA	Polyadenylate-binding protein 1-A	2209558	The Xenopus laevis poly(A) binding protein is composed of multiple functionally independent RNA binding domains.

P0AEC3	ARCB_ECOLI	Aerobic respiration control sensor protein ArcB	2201868	The arcB gene of Escherichia coli encodes a sensor-regulator protein for anaerobic repression of the arc modulon.

P70347	TANK_MOUSE	TRAF family member-associated NF-kappa-B activator	8710854	I-TRAF is a novel TRAF-interacting protein that regulates TRAF- mediated signal transduction.

P24814	GRR1_YEAST	SCF E3 ubiquitin ligase complex F-box protein GRR1	10213692	Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1.

Q9US59	SKB5_SCHPO	Shk1 kinase-binding protein 5	10593886	Direct activation of the fission yeast PAK Shk1 by the novel SH3 domain protein, Skb5.

Q9P6M3	MIS14_SCHPO	Kinetochore protein mis14	17035632	Reconstruction of the kinetochore during meiosis in fission yeast Schizosaccharomyces pombe.

Q07794	RT109_YEAST	Histone acetyltransferase RTT109	17046836	Rtt109 is required for proper H3K56 acetylation: a chromatin mark associated with the elongating RNA polymerase II.

P23458	JAK1_HUMAN	Tyrosine-protein kinase JAK1	1848670	Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase.

O95376	ARI2_HUMAN	E3 ubiquitin-protein ligase ARIH2	19340006	The ubiquitin ligase Triad1 inhibits myelopoiesis through UbcH7 and Ubc13 interacting domains.

B2RUP2	UN13D_MOUSE	Protein unc-13 homolog D	17420270	Jinx, an MCMV susceptibility phenotype caused by disruption of Unc13d: a mouse model of type 3 familial hemophagocytic lymphohistiocytosis.

Q94AI7	TPL_ARATH	Protein TOPLESS	18258861	TOPLESS mediates auxin-dependent transcriptional repression during Arabidopsis embryogenesis.

Q99PI4	LPIN3_MOUSE	Phosphatidate phosphatase LPIN3	17158099	Three mammalian lipins act as phosphatidate phosphatases with distinct tissue expression patterns.

Q6BDR8	NSE4_SCHPO	Non-structural maintenance of chromosome element 4	15331764	Nse1, Nse2, and a novel subunit of the Smc5-Smc6 complex, Nse3, play a crucial role in meiosis.

Q9BQE4	SELS_HUMAN	Selenoprotein S	15215856	A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol.

Q14865	ARI5B_HUMAN	AT-rich interactive domain-containing protein 5B	15640446	DNA-binding properties of ARID family proteins.

Q38967	AAP2_ARATH	Amino acid permease 2	8281191	Differential expression of two related amino acid transporters with differing substrate specificity in Arabidopsis thaliana.

Q9XZT6	DNK_DROME	Deoxynucleoside kinase	10692477	Functional expression of a multisubstrate deoxyribonucleoside kinase from Drosophila melanogaster and its C-terminal deletion mutants.

Q9JKQ4	IRX5_MOUSE	Iroquois-class homeodomain protein IRX-5	16182275	The Iroquois homeobox gene, Irx5, is required for retinal cone bipolar cell development.

Q7Z2Z1	TICRR_HUMAN	Treslin	20116089	Treslin collaborates with TopBP1 in triggering the initiation of DNA replication.

Q9WTK7	STK11_MOUSE	Serine/threonine-protein kinase 11	10400995	The mouse Peutz-Jeghers syndrome gene Lkb1 encodes a nuclear protein kinase.

Q43157	RPE_SPIOL	Ribulose-phosphate 3-epimerase, chloroplastic	9523694	Purification, properties and in situ localization of the amphibolic enzymes D-ribulose 5-phosphate 3-epimerase and transketolase from spinach chloroplasts.

O60129	FKH2_SCHPO	Fork head protein homolog 2	15302827	The forkhead transcription factor Fkh2 regulates the cell division cycle of Schizosaccharomyces pombe.

P38274	HSL7_YEAST	Protein arginine N-methyltransferase HSL7	10903903	Hsl7p, the yeast homologue of human JBP1, is a protein methyltransferase.

Q06678	RM35_YEAST	54S ribosomal protein L35, mitochondrial	9151978	Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae.

Q13214	SEM3B_HUMAN	Semaphorin-3B	8633026	Human semaphorins A(V) and IV reside in the 3p21.3 small cell lung cancer deletion region and demonstrate distinct expression patterns.

Q15075	EEA1_HUMAN	Early endosome antigen 1	10506127	The Rab5 effector EEA1 interacts directly with syntaxin-6.

P13852	PRIO_RAT	Major prion protein	10373359	Analysis of 27 mammalian and 9 avian PrPs reveals high conservation of flexible regions of the prion protein.

O75821	EIF3G_HUMAN	Eukaryotic translation initiation factor 3 subunit G	17581632	Reconstitution reveals the functional core of mammalian eIF3.

P24587	AKAP5_RAT	A-kinase anchor protein 5	2538452	High affinity binding protein for the regulatory subunit of cAMP- dependent protein kinase II-B. Cloning, characterization, and expression of cDNAs for rat brain P150.

Q01196	RUNX1_HUMAN	Runt-related transcription factor 1	9199349	A novel transcript encoding an N-terminally truncated AML1/PEBP2 alphaB protein interferes with transactivation and blocks granulocytic differentiation of 32Dcl3 myeloid cells.

Q02721	RE102_YEAST	Meiotic recombination protein REC102	1732169	The rec102 mutant of yeast is defective in meiotic recombination and chromosome synapsis.

P25491	MAS5_YEAST	Mitochondrial protein import protein MAS5	1729605	MAS5, a yeast homolog of DnaJ involved in mitochondrial protein import.

Q9C801	MOS2_ARATH	Protein MOS2	16271871	MOS2, a protein containing G-patch and KOW motifs, is essential for innate immunity in Arabidopsis thaliana.

Q6P179	ERAP2_HUMAN	Endoplasmic reticulum aminopeptidase 2	12799365	Human leukocyte-derived arginine aminopeptidase. The third member of the oxytocinase subfamily of aminopeptidases.

O70600	RSAD2_RAT	Radical S-adenosyl methionine domain-containing protein 2	10698968	Best5: a novel interferon-inducible gene expressed during bone formation.

P59761	LGEN_BOVIN	Lactogenin	11105990	First demonstration of an inhibitory activity of milk proteins against human immunodeficiency virus-1 reverse transcriptase and the effect of succinylation.

Q9UQ13	SHOC2_HUMAN	Leucine-rich repeat protein SHOC-2	16630891	A phosphatase holoenzyme comprised of Shoc2/Sur8 and the catalytic subunit of PP1 functions as an M-Ras effector to modulate Raf activity.

Q16635	TAZ_HUMAN	Tafazzin	12930833	Only one splice variant of the human TAZ gene encodes a functional protein with a role in cardiolipin metabolism.

O35158	CDON_RAT	Cell adhesion molecule-related/down-regulated by oncogenes	9214393	CDO: an oncogene-, serum-, and anchorage-regulated member of the Ig/fibronectin type III repeat family.

O88597	BECN1_MOUSE	Beclin-1	12372286	A novel protein complex linking the delta 2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice.

Q9GUM2	BRE4_CAEEL	Beta-1,4-N-acetylgalactosaminyltransferase bre-4	10924467	Bacillus thuringiensis (Bt) toxin susceptibility and isolation of resistance mutants in the nematode Caenorhabditis elegans.

O82796	SERB_ARATH	Phosphoserine phosphatase, chloroplastic	10196182	Plastidic pathway of serine biosynthesis. Molecular cloning and expression of 3-phosphoserine phosphatase from Arabidopsis thaliana.

P35612	ADDB_HUMAN	Beta-adducin	1840603	Primary structure and domain organization of human alpha and beta adducin.

P23497	SP100_HUMAN	Nuclear autoantigen Sp-100	16177824	Mediation of Epstein-Barr virus EBNA-LP transcriptional coactivation by Sp100.

P50273	ATP22_YEAST	Mitochondrial translation factor ATP22	12646576	ATP22, a nuclear gene required for expression of the F0 sector of mitochondrial ATPase in Saccharomyces cerevisiae.

Q3SYG4	PTHB1_HUMAN	Protein PTHB1	17574030	A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis.

O14008	CAM2_SCHPO	Myosin 1 light chain cam2	15504913	UCS protein Rng3p activates actin filament gliding by fission yeast myosin-II.

P51854	TKTL1_HUMAN	Transketolase-like protein 1	8838793	Molecular cloning of tissue-specific transcripts of a transketolase- related gene: implications for the evolution of new vertebrate genes.

P11473	VDR_HUMAN	Vitamin D3 receptor	2849209	Point mutations in the human vitamin D receptor gene associated with hypocalcemic rickets.

O44712	AHR_CAEEL	Aryl hydrocarbon receptor protein 1	9501178	Caenorhabditis elegans orthologs of the aryl hydrocarbon receptor and its heterodimerization partner the aryl hydrocarbon receptor nuclear translocator.

O94300	YOOH_SCHPO	Putative xanthine/uracil permease C887.17	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q80T02	GPBAR_RAT	G-protein coupled bile acid receptor 1	12524422	A G protein-coupled receptor responsive to bile acids.

Q8W207	CSN2_ARATH	COP9 signalosome complex subunit 2	12615944	Characterization of the last subunit of the Arabidopsis COP9 signalosome: implications for the overall structure and origin of the complex.

P31057	PANB_ECOLI	3-methyl-2-oxobutanoate hydroxymethyltransferase	6463	Ketopantoate hydroxymethyltransferase. II. Physical, catalytic, and regulatory properties.

P0C8M2	CBP_MESMA	Serine proteinase-like BMK-CBP	18625260	Purification and N-terminal sequence of a serine proteinase-like protein (BMK-CBP) from the venom of the Chinese scorpion (Buthus martensii Karsch).

Q9Y6C2	EMIL1_HUMAN	EMILIN-1	10358019	EMILIN, a component of the elastic fiber and a new member of the C1q/tumor necrosis factor superfamily of proteins.

Q5YD76	B1HA_LOXBO	Sphingomyelin phosphodiesterase D LbSicTox-betaIA1a	15450925	Genetic and enzymatic characterization of sphingomyelinase D isoforms from the North American fiddleback spiders Loxosceles boneti and Loxosceles reclusa.

P50552	VASP_HUMAN	Vasodilator-stimulated phosphoprotein	7828592	Molecular cloning, structural analysis and functional expression of the proline-rich focal adhesion and microfilament-associated protein VASP.

Q9D5V2	KLH10_MOUSE	Kelch-like protein 10	15136734	Haploinsufficiency of kelch-like protein homolog 10 causes infertility in male mice.

P38428	CUE1_YEAST	Coupling of ubiquitin conjugation to ER degradation protein 1	12628920	A ubiquitin-binding motif required for intramolecular monoubiquitylation, the CUE domain.

P83186	BRA_BASAL	Alpha-basrubrin	11688973	Novel antifungal peptides from ceylon spinach seeds.

P43003	EAA1_HUMAN	Excitatory amino acid transporter 1	7521911	Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex.

Q9H227	GBA3_HUMAN	Cytosolic beta-glucosidase	17595169	Klotho-related protein is a novel cytosolic neutral beta- glycosylceramidase.

Q08345	DDR1_HUMAN	Epithelial discoidin domain-containing receptor 1	18190796	KIBRA interacts with discoidin domain receptor 1 to modulate collagen-induced signalling.

O62479	SAS6_CAEEL	Spindle assembly abnormal protein 6	15665853	SAS-6 defines a protein family required for centrosome duplication in C. elegans and in human cells.

Q14204	DYHC1_HUMAN	Cytoplasmic dynein 1 heavy chain 1	8227145	Cytoplasmic dynein plays a role in mammalian mitotic spindle formation.

Q2R3B4	GH313_ORYSJ	Probable indole-3-acetic acid-amido synthetase GH3.13	16488558	The GH3 family in plants: genome wide analysis in rice and evolutionary history based on EST analysis.

Q9NII1	ADAR_DROME	Double-stranded RNA-specific editase Adar	10966106	A-to-I pre-mRNA editing in Drosophila is primarily involved in adult nervous system function and integrity.

Q7TMD7	DSG4_MOUSE	Desmoglein-4	12705872	Desmoglein 4 in hair follicle differentiation and epidermal adhesion. Evidence from inherited hypotrichosis and acquired pemphigus vulgaris.

P25553	ALDA_ECOLI	Lactaldehyde dehydrogenase	3308886	Involvement of lactaldehyde dehydrogenase in several metabolic pathways of Escherichia coli K12.

Q96DT0	LEG12_HUMAN	Galectin-12	11435439	Galectin-12, an adipose-expressed galectin-like molecule possessing apoptosis-inducing activity.

Q9NVC6	MED17_HUMAN	Mediator of RNA polymerase II transcription subunit 17	10198638	Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators.

Q10156	LKH1_SCHPO	Dual specificity protein kinase lkh1	11741326	Negative regulation of filamentous growth and flocculation by Lkh1, a fission yeast LAMMER kinase homolog.

P04637	P53_HUMAN	Cellular tumor antigen p53	12702766	Characterization of cells and gene-targeted mice deficient for the p53-binding kinase homeodomain-interacting protein kinase 1 (HIPK1).

Q9T020	Y4391_ARATH	Probable receptor-like protein kinase At4g39110	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q90Z12	HES4A_XENLA	Transcription factor HES-4-A	14681193	Interplay between Notch signaling and the homeoprotein Xiro1 is required for neural crest induction in Xenopus embryos.

O14089	IMB2_SCHPO	Importin subunit beta-2	15116432	Identification of genes encoding putative nucleoporins and transport factors in the fission yeast Schizosaccharomyces pombe: a deletion analysis.

Q96H20	SNF8_HUMAN	Vacuolar-sorting protein SNF8	10419521	Cloning and characterization of the EAP30 subunit of the ELL complex that confers derepression of transcription by RNA polymerase II.

Q62715	DEF2_RAT	Neutrophil antibiotic peptide NP-2	7594610	Rat neutrophil defensins. Precursor structures and expression during neutrophilic myelopoiesis.

P97875	JDP2_MOUSE	Jun dimerization protein 2	11231009	Identification of mouse Jun dimerization protein 2 as a novel repressor of ATF-2.

O15111	IKKA_HUMAN	Inhibitor of nuclear factor kappa-B kinase subunit alpha	9520446	NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176.

P19544	WT1_HUMAN	Wilms tumor protein	8393820	The WT1 Wilms tumor gene product: a developmentally regulated transcription factor in the kidney that functions as a tumor suppressor.

P05231	IL6_HUMAN	Interleukin-6	3023045	Structure and expression of cDNA and genes for human interferon-beta- 2, a distinct species inducible by growth-stimulatory cytokines.

P40501	AVT7_YEAST	Vacuolar amino acid transporter 7	11274162	A family of yeast proteins mediating bidirectional vacuolar amino acid transport.

P46098	5HT3A_HUMAN	5-hydroxytryptamine receptor 3A	7565620	Molecular cloning of human 5-hydroxytryptamine3 receptor: heterogeneity in distribution and function among species.

Q08282	LCMT2_YEAST	Leucine carboxyl methyltransferase 2	16642040	Biosynthesis of wybutosine, a hyper-modified nucleoside in eukaryotic phenylalanine tRNA.

Q6IFW3	K1C39_RAT	Keratin, type I cytoskeletal 39	15085952	Comprehensive analysis of keratin gene clusters in humans and rodents.

Q8TEU7	RPGF6_HUMAN	Rap guanine nucleotide exchange factor 6	11524421	Identification and characterization of RA-GEF-2, a Rap guanine nucleotide exchange factor that serves as a downstream target of M- Ras.

O15127	SCAM2_HUMAN	Secretory carrier-associated membrane protein 2	9378760	Three mammalian SCAMPs (secretory carrier membrane proteins) are highly related products of distinct genes having similar subcellular distributions.

Q12284	ERV2_YEAST	FAD-linked sulfhydryl oxidase ERV2	11313344	Yeast ERV2p is the first microsomal FAD-linked sulfhydryl oxidase of the Erv1p/Alrp protein family.

Q8VZT6	TRL32_ARATH	Thioredoxin-like 3-2, chloroplastic	19259774	A novel extended family of stromal thioredoxins.

Q13217	DNJC3_HUMAN	DnaJ homolog subfamily C member 3	8666242	Cloning, expression, and cellular localization of the oncogenic 58- kDa inhibitor of the RNA-activated human and mouse protein kinase.

Q9UBJ2	ABCD2_HUMAN	ATP-binding cassette sub-family D member 2	10704444	PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis.

P53840	TOF1_YEAST	Topoisomerase 1-associated factor 1	16219777	Genetic analysis of Saccharomyces cerevisiae H2A serine 129 mutant suggests a functional relationship between H2A and the sister- chromatid cohesion partners Csm3-Tof1 for the repair of topoisomerase I-induced DNA damage.

Q8IUD6	RN135_HUMAN	E3 ubiquitin-protein ligase RNF135	19881509	PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4.

Q9NPE3	NOP10_HUMAN	H/ACA ribonucleoprotein complex subunit 3	16601202	hNaf1 is required for accumulation of human box H/ACA snoRNPs, scaRNPs, and telomerase.

Q9UBG3	CRNN_HUMAN	Cornulin	11056050	Novel human esophagus-specific gene c1orf10: cDNA cloning, gene structure, and frequent loss of expression in esophageal cancer.

P38325	OM14_YEAST	Mitochondrial outer membrane protein OM14	16689936	Integral membrane proteins in the mitochondrial outer membrane of Saccharomyces cerevisiae.

O88509	DNM3B_MOUSE	DNA (cytosine-5)-methyltransferase 3B	18567530	DNA methyltransferase 3B acts as a co-repressor of the human polycomb protein hPc2 to repress fibroblast growth factor receptor 3 transcription.

Q9XS63	CMGA_HORSE	Chromogranin-A	11039590	Molecular cloning of equine chromogranin A and its expression in endocrine and exocrine tissues.

Q9NFU0	FMR1_DROME	Fragile X mental retardation syndrome-related protein 1	15183715	The Drosophila fragile X-related gene regulates axoneme differentiation during spermatogenesis.

Q5DT21	ISK9_HUMAN	Serine protease inhibitor Kazal-type 9	19194479	SPINK9: a selective, skin-specific Kazal-type serine protease inhibitor.

P02458	CO2A1_HUMAN	Collagen alpha-1(II) chain	8660302	Collagen type IX from human cartilage: a structural profile of intermolecular cross-linking sites.

O14089	IMB2_SCHPO	Importin subunit beta-2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O59782	SULH3_SCHPO	Probable sulfate permease C320.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9JKB3	DBPA_MOUSE	DNA-binding protein A	10772793	A sequence-specific RNA binding complex expressed in murine germ cells contains MSY2 and MSY4.

O74434	MU174_SCHPO	Meiotically up-regulated gene 174 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P49711	CTCF_HUMAN	Transcriptional repressor CTCF	18347100	The insulator factor CTCF controls MHC class II gene expression and is required for the formation of long-distance chromatin interactions.

Q925P2	CEAM2_MOUSE	Carcinoembryonic antigen-related cell adhesion molecule 2	8207827	Bgp2, a new member of the carcinoembryonic antigen-related gene family, encodes an alternative receptor for mouse hepatitis viruses.

Q9Y4Y9	LSM5_HUMAN	U6 snRNA-associated Sm-like protein LSm5	10369684	Sm and Sm-like proteins assemble in two related complexes of deep evolutionary origin.

P04799	CP1A2_RAT	Cytochrome P450 1A2	2985574	Complete nucleotide sequence of a methylcholanthrene-inducible cytochrome P-450 (P-450d) gene in the rat.

P38827	SET1_YEAST	Histone-lysine N-methyltransferase, H3 lysine-4 specific	9398665	SET1, a yeast member of the Trithorax family, functions in transcriptional silencing and diverse cellular processes.

Q13310	PABP4_HUMAN	Polyadenylate-binding protein 4	8524242	iPABP, an inducible poly(A)-binding protein detected in activated human T cells.

Q9NRY4	GRLF1_HUMAN	Glucocorticoid receptor DNA-binding factor 1	1894621	Molecular cloning and characterization of a factor that binds the human glucocorticoid receptor gene and represses its expression.

O14299	WIS4_SCHPO	MAP kinase kinase kinase wis4	9188094	Mcs4 mitotic catastrophe suppressor regulates the fission yeast cell cycle through the Wik1-Wis1-Spc1 kinase cascade.

Q09826	SDS23_SCHPO	Protein sds23/moc1	9242669	A novel protein, Psp1, essential for cell cycle progression of Schizosaccharomyces pombe is phosphorylated by Cdc2-Cdc13 upon entry into G0-like stationary phase of cell growth.

Q9NQZ3	DAZ1_HUMAN	Deleted in azoospermia protein 1	12511597	Human Pumilio-2 is expressed in embryonic stem cells and germ cells and interacts with DAZ (Deleted in AZoospermia) and DAZ-like proteins.

P55884	EIF3B_HUMAN	Eukaryotic translation initiation factor 3 subunit B	8995410	The human homologue of the yeast Prt1 protein is an integral part of the eukaryotic initiation factor 3 complex and interacts with p170.

Q9NPF2	CHSTB_HUMAN	Carbohydrate sulfotransferase 11	11056388	Molecular cloning, expression, and chromosomal mapping of human chondroitin 4-sulfotransferase, whose expression pattern in human tissues is different from that of chondroitin 6-sulfotransferase.

P0ADE8	YGFZ_ECOLI	tRNA-modifying protein ygfZ	16359333	Involvement of the Escherichia coli folate-binding protein YgfZ in RNA modification and regulation of chromosomal replication initiation.

P31390	HRH1_RAT	Histamine H1 receptor	7678492	Genomic cloning of the rat histamine H1 receptor.

Q9BVA1	TBB2B_HUMAN	Tubulin beta-2B chain	19465910	Mutations in the beta-tubulin gene TUBB2B result in asymmetrical polymicrogyria.

Q86BY9	RIG_DROME	Protein rigor mortis	14645129	rigor mortis encodes a novel nuclear receptor interacting protein required for ecdysone signaling during Drosophila larval development.

Q8RVQ9	HTR12_ARATH	Histone H3-like centromeric protein HTR12	17242155	VIM1, a methylcytosine-binding protein required for centromeric heterochromatinization.

P48728	GCST_HUMAN	Aminomethyltransferase, mitochondrial	9600239	A missense mutation (His42Arg) in the T-protein gene from a large Israeli-Arab kindred with nonketotic hyperglycinemia.

Q01484	ANK2_HUMAN	Ankyrin-2	15262991	Ankyrin-B targets beta2-spectrin to an intracellular compartment in neonatal cardiomyocytes.

Q6NLQ6	CDPKW_ARATH	Calcium-dependent protein kinase 32	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q8INB9	AKT1_DROME	RAC serine/threonine-protein kinase	14525946	Coordinated functions of Akt/PKB and ETS1 in tubule formation.

P08018	PBS2_YEAST	MAP kinase kinase PBS2	7681220	An osmosensing signal transduction pathway in yeast.

O60187	SID4_SCHPO	Septation initiation protein sid4	11676915	S. pombe cdc11p, together with sid4p, provides an anchor for septation initiation network proteins on the spindle pole body.

Q13905	RPGF1_HUMAN	Rap guanine nucleotide exchange factor 1	7512734	C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins.

Q95Q95	TOR_CAEEL	Target of rapamycin homolog	12225660	TOR deficiency in C. elegans causes developmental arrest and intestinal atrophy by inhibition of mRNA translation.

Q06628	ATG13_YEAST	Autophagy-related protein 13	10995454	Tor-mediated induction of autophagy via an Apg1 protein kinase complex.

O96019	ACL6A_HUMAN	Actin-like protein 6A	14966270	Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans.

P83526	FER_TOBAC	Ferredoxin	9989672	Protein chemotaxonomy of the solanaceae. VI. Amino acid sequence of ferredoxin from Nicotian tabacum.

Q9M384	SCR_ARATH	Protein SCARECROW	15314023	Mosaic analyses using marked activation and deletion clones dissect Arabidopsis SCARECROW action in asymmetric cell division.

Q3E840	DPH3_YEAST	Diphthamide biosynthesis protein 3	15485916	Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2.

Q14117	DPYS_HUMAN	Dihydropyrimidinase	9718352	Dihydropyrimidinase deficiency: structural organization, chromosomal localization, and mutation analysis of the human dihydropyrimidinase gene.

P27797	CALR_HUMAN	Calreticulin	1911778	In vitro interaction of a polypeptide homologous to human Ro/SS-A antigen (calreticulin) with a highly conserved amino acid sequence in the cytoplasmic domain of integrin alpha subunits.

Q9UK28	TM59L_HUMAN	Transmembrane protein 59-like	10527841	BSMAP, a novel protein expressed specifically in the brain whose gene is localized on chromosome 19p12.

P13444	METK1_RAT	S-adenosylmethionine synthase isoform type-1	12888348	Crystal structures of methionine adenosyltransferase complexed with substrates and products reveal the methionine-ATP recognition and give insights into the catalytic mechanism.

Q9P6R4	MU172_SCHPO	Meiotically up-regulated gene 172 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12186	BBP_YEAST	Branchpoint-bridging protein	9150140	Cross-intron bridging interactions in the yeast commitment complex are conserved in mammals.

P0A6D5	YDIB_ECOLI	Quinate/shikimate dehydrogenase	15596430	Site-directed mutagenesis of the active site region in the quinate/shikimate 5-dehydrogenase YdiB of Escherichia coli.

Q91VB4	HPS3_MOUSE	Hermansky-Pudlak syndrome 3 protein homolog	11707070	The gene mutated in cocoa mice, carrying a defect of organelle biogenesis, is a homologue of the human Hermansky-Pudlak syndrome-3 gene.

Q09739	MCP7_SCHPO	Meiotic coiled-coil protein 7	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

Q39232	SUC1_ARATH	Sucrose transport protein SUC1	15215502	Isolation of intact vacuoles and proteomic analysis of tonoplast from suspension-cultured cells of Arabidopsis thaliana.

Q62763	KC1G3_RAT	Casein kinase I isoform gamma-3	7759525	Casein kinase I gamma subfamily. Molecular cloning, expression, and characterization of three mammalian isoforms and complementation of defects in the Saccharomyces cerevisiae YCK genes.

P32414	ES1_RANES	Esculentin-1	8508915	Novel antimicrobial peptides from skin secretion of the European frog Rana esculenta.

Q9QZS2	RNF4_MOUSE	E3 ubiquitin ligase RNF4	12885770	The RING finger protein RNF4, a co-regulator of transcription, interacts with the TRPS1 transcription factor.

Q2PJ68	SGK1_CAEEL	Serine/threonine-protein kinase sgk-1	18358814	Direct inhibition of the longevity-promoting factor SKN-1 by insulin- like signaling in C. elegans.

O13899	YF38_SCHPO	Uncharacterized CDP-alcohol phosphatidyltransferase class-I family protein C22A12.08c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8AWF4	NUF2A_XENLA	Kinetochore protein Nuf2-A	12514103	The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity.

P62249	RS16_HUMAN	40S ribosomal protein S16	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

P54642	VATL_DICDI	V-type proton ATPase proteolipid subunit	8838672	Antisense RNA inhibition of the putative vacuolar H(+)-ATPase proteolipid of Dictyostelium reduces intracellular Ca2+ transport and cell viability.

P33232	LLDD_ECOLI	L-lactate dehydrogenase [cytochrome]	8407843	Three overlapping lct genes involved in L-lactate utilization by Escherichia coli.

P05651	RECF_BACSU	DNA replication and repair protein recF	15186413	Visualization of DNA double-strand break repair in live bacteria reveals dynamic recruitment of Bacillus subtilis RecF, RecO and RecN proteins to distinct sites on the nucleoids.

Q54GT9	ATG5_DICDI	Autophagy protein 5	12626495	Macroautophagy is required for multicellular development of the social amoeba Dictyostelium discoideum.

Q62141	SIN3B_MOUSE	Paired amphipathic helix protein Sin3b	11909966	Identification of mammalian Sds3 as an integral component of the Sin3/histone deacetylase corepressor complex.

P38203	LSM2_YEAST	U6 snRNA-associated Sm-like protein LSm2	10369684	Sm and Sm-like proteins assemble in two related complexes of deep evolutionary origin.

P52890	ATF1_SCHPO	Transcription factor atf1	7958849	A heteromeric protein that binds to a meiotic homologous recombination hot spot: correlation of binding and hot spot activity.

P51142	DVL2_XENLA	Segment polarity protein dishevelled homolog DVL-2	10688669	Interaction of dishevelled and Xenopus axin-related protein is required for wnt signal transduction.

Q15973	ZN124_HUMAN	Zinc finger protein 124	7916577	A novel zinc finger gene on human chromosome 1qter that is alternatively spliced in human tissues and cell lines.

Q1AGV6	SDC4B_XENLA	Syndecan 4-B	17041718	xSyndecan-4 regulates gastrulation and neural tube closure in Xenopus embryos.

P22217	TRX1_YEAST	Thioredoxin-1	11169096	Role of the glutathione/glutaredoxin and thioredoxin systems in yeast growth and response to stress conditions.

P48411	IL10_CANFA	Interleukin-10	8746793	Cloning and expression of canine interleukin-10.

P07806	SYV_YEAST	Valyl-tRNA synthetase, mitochondrial	3275649	The yeast VAS1 gene encodes both mitochondrial and cytoplasmic valyl- tRNA synthetases.

O15111	IKKA_HUMAN	Inhibitor of nuclear factor kappa-B kinase subunit alpha	9346484	IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF- kappaB activation.

O22218	ACA4_ARATH	Calcium-transporting ATPase 4, plasma membrane-type	11115896	The ACA4 gene of Arabidopsis encodes a vacuolar membrane calcium pump that improves salt tolerance in yeast.

P40210	SIP5_YEAST	Protein SIP5	10628972	Sip5 interacts with both the Reg1/Glc7 protein phosphatase and the Snf1 protein kinase of Saccharomyces cerevisiae.

Q9LSX8	ASK10_ARATH	SKP1-like protein 10	12970487	Members of the Arabidopsis-SKP1-like gene family exhibit a variety of expression patterns and may play diverse roles in Arabidopsis.

O00213	APBB1_HUMAN	Amyloid beta A4 precursor protein-binding family B member 1	17686488	Structural basis for polyproline recognition by the FE65 WW domain.

P0C2S1	CELK_CLOTM	Cellulose 1,4-beta-cellobiosidase	8664281	Dissociation of the cellulosome of Clostridium thermocellum in the presence of ethylenediaminetetraacetic acid occurs with the formation of trucated polypeptides.

Q6PHU5	SORT_MOUSE	Sortilin	15992544	Sortilin is essential and sufficient for the formation of Glut4 storage vesicles in 3T3-L1 adipocytes.

Q5H9R7	PP6R3_HUMAN	Serine/threonine-protein phosphatase 6 regulatory subunit 3	18186651	Protein phosphatase 6 regulatory subunits composed of ankyrin repeat domains.

P34948	MPI_CANAL	Mannose-6-phosphate isomerase	8180205	Arginine 304 is an active site residue in phosphomannose isomerase from Candida albicans.

Q9NZD4	AHSP_HUMAN	Alpha-hemoglobin-stabilizing protein	12066189	An abundant erythroid protein that stabilizes free alpha- haemoglobin.

Q3MKP9	BEX4_RAT	Protein BEX4	15958283	Characterization of the Bex gene family in humans, mice, and rats.

P48995	TRPC1_HUMAN	Short transient receptor potential channel 1	7568191	TRPC1, a human homolog of a Drosophila store-operated channel.

Q9V3C1	VHL_DROME	Protein Vhl	11006129	Drosophila von Hippel-Lindau tumor suppressor complex possesses E3 ubiquitin ligase activity.

Q6INX3	MLECA_XENLA	Malectin-A	18524852	Malectin: a novel carbohydrate-binding protein of the endoplasmic reticulum and a candidate player in the early steps of protein N- glycosylation.

P53367	ARFP1_HUMAN	Arfaptin-1	9038142	Arfaptin 1, a putative cytosolic target protein of ADP-ribosylation factor, is recruited to Golgi membranes.

P63331	PP2AA_RAT	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform	2461222	Molecular cloning of cDNA for the catalytic subunit of rat liver type 2A protein phosphatase, and detection of high levels of expression of the gene in normal and cancer cells.

O14497	ARI1A_HUMAN	AT-rich interactive domain-containing protein 1A	10757798	The human SWI-SNF complex protein p270 is an ARID family member with non-sequence-specific DNA binding activity.

Q9M1K3	SIP21_ARATH	Probable aquaporin SIP2-1	16223486	Novel type aquaporin SIPs are mainly localized to the ER membrane and show cell-specific expression in Arabidopsis thaliana.

Q3UN02	LCLT1_MOUSE	Lysocardiolipin acyltransferase 1	15152008	A novel cardiolipin-remodeling pathway revealed by a gene encoding an endoplasmic reticulum-associated acyl-CoA:lysocardiolipin acyltransferase (ALCAT1) in mouse.

Q04603	DPB4_YEAST	DNA polymerase epsilon subunit D	11024162	Structure and function of the fourth subunit (Dpb4p) of DNA polymerase epsilon in Saccharomyces cerevisiae.

Q96EB6	SIRT1_HUMAN	NAD-dependent deacetylase sirtuin-1	12006491	Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence.

Q7KRI2	LOLAL_DROME	Longitudinals lacking protein-like	12556479	Batman interacts with polycomb and trithorax group genes and encodes a BTB/POZ protein that is included in a complex containing GAGA factor.

Q9UTP4	YLL3_SCHPO	Smr domain-containing protein C11H11.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12098	SLX4_YEAST	Structure-specific endonuclease subunit SLX4	12228808	Role of SGS1 and SLX4 in maintaining rDNA structure in Saccharomyces cerevisiae.

Q16772	GSTA3_HUMAN	Glutathione S-transferase A3	9480897	Identification of cDNAs encoding two human alpha class glutathione transferases (GSTA3 and GSTA4) and the heterologous expression of GSTA4-4.

P04925	PRIO_MOUSE	Major prion protein	9837873	Copper stimulates endocytosis of the prion protein.

P47136	BUD4_YEAST	Bud site selection protein 4	12176366	Subcellular localization of Axl1, the cell type-specific regulator of polarity.

P17050	NAGAB_HUMAN	Alpha-N-acetylgalactosaminidase	9741689	Degradation of blood group A glycolipid A-6-2 by normal and mutant human skin fibroblasts.

Q99MV1	TDRD1_MOUSE	Tudor domain-containing protein 1	14550528	Mouse Tudor Repeat-1 (MTR-1) is a novel component of chromatoid bodies/nuages in male germ cells and forms a complex with snRNPs.

O43772	MCAT_HUMAN	Mitochondrial carnitine/acylcarnitine carrier protein	9399886	Cloning of the human carnitine-acylcarnitine carrier cDNA and identification of the molecular defect in a patient.

P21816	CDO1_RAT	Cysteine dioxygenase type 1	8973325	Structural organization and tissue-specific expression of the gene encoding rat cysteine dioxygenase.

P03891	NU2M_HUMAN	NADH-ubiquinone oxidoreductase chain 2	9475751	Departure from neutrality at the mitochondrial NADH dehydrogenase subunit 2 gene in humans, but not in chimpanzees.

P32320	CDD_HUMAN	Cytidine deaminase	7923172	Human cytidine deaminase: purification of enzyme, cloning, and expression of its complementary DNA.

O00505	IMA3_HUMAN	Importin subunit alpha-3	9154134	Isolation and mapping of karyopherin alpha 3 (KPNA3), a human gene that is highly homologous to genes encoding Xenopus importin, yeast SRP1 and human RCH1.

Q9LZM8	BLH9_ARATH	BEL1-like homeodomain protein 9	12897247	The interaction of two homeobox genes, BREVIPEDICELLUS and PENNYWISE, regulates internode patterning in the Arabidopsis inflorescence.

Q940J9	PMT8_ARATH	Probable methyltransferase PMT8	16618929	Mapping the Arabidopsis organelle proteome.

O14773	TPP1_HUMAN	Tripeptidyl-peptidase 1	9295267	Association of mutations in a lysosomal protein with classical late- infantile neuronal ceroid lipofuscinosis.

Q9BT40	INP5K_HUMAN	Inositol polyphosphate 5-phosphatase K	12536145	Identification of a novel domain in two mammalian inositol- polyphosphate 5-phosphatases that mediates membrane ruffle localization. The inositol 5-phosphatase SKIP localizes to the endoplasmic reticulum and translocates to membrane ruffles following epidermal growth factor stimulation.

O13756	VPS8_SCHPO	Vacuolar protein sorting-associated protein 8	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9LVI6	RLK90_ARATH	Probable inactive receptor kinase RLK902	15618630	Identification of three clones which commonly interact with the kinase domains of highly homologous two receptor-like kinases, RLK902 and RKL1.

P53634	CATC_HUMAN	Dipeptidyl peptidase 1	9092576	Human dipeptidyl-peptidase I. Gene characterization, localization, and expression.

P26358	DNMT1_HUMAN	DNA (cytosine-5)-methyltransferase 1	19450230	SUMOylation enhances DNA methyltransferase 1 activity.

P85005	PROAT_PROSR	Proatherocytin	16112700	Characterization of a novel protein from Proatheris superciliaris venom: proatherocytin, a 34-kDa platelet receptor PAR1 agonist.

Q8WWN8	ARAP3_HUMAN	Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3	15569923	EST-based genome-wide gene inactivation identifies ARAP3 as a host protein affecting cellular susceptibility to anthrax toxin.

P70279	SURF6_MOUSE	Surfeit locus protein 6	8639267	The Surf-6 gene of the mouse surfeit locus encodes a novel nucleolar protein.

Q9FUY2	LEUNG_ARATH	Transcriptional corepressor LEUNIG	11058164	LEUNIG, a putative transcriptional corepressor that regulates AGAMOUS expression during flower development.

Q29RF7	PDS5A_HUMAN	Sister chromatid cohesion protein PDS5 homolog A	15855230	Functional contribution of Pds5 to cohesin-mediated cohesion in human cells and Xenopus egg extracts.

P38112	MAK5_YEAST	ATP-dependent RNA helicase MAK5	13680366	Mak5p, which is required for the maintenance of the M1 dsRNA virus, is encoded by the yeast ORF YBR142w and is involved in the biogenesis of the 60S subunit of the ribosome.

P10127	ADH4_YEAST	Alcohol dehydrogenase 4	3282541	Overexpression, purification and properties of alcohol dehydrogenase IV from Saccharomyces cerevisiae.

Q02789	CAC1S_MOUSE	Voltage-dependent L-type calcium channel subunit alpha-1S	1281468	A single nucleotide deletion in the skeletal muscle-specific calcium channel transcript of muscular dysgenesis (mdg) mice.

P08729	K2C7_HUMAN	Keratin, type II cytoskeletal 7	2459129	Isolation, sequence, and differential expression of a human K7 gene in simple epithelial cells.

Q14571	ITPR2_HUMAN	Inositol 1,4,5-trisphosphate receptor type 2	8081734	Cloning and characterization of human type 2 and type 3 inositol 1,4,5-trisphosphate receptors.

Q8CFZ5	S22AC_MOUSE	Solute carrier family 22 member 12	14747372	Function and localization of urate transporter 1 in mouse kidney.

P24885	NU6M_CAEEL	NADH-ubiquinone oxidoreductase chain 6	1551572	The mitochondrial genomes of two nematodes, Caenorhabditis elegans and Ascaris suum.

P09215	KPCD_RAT	Protein kinase C delta type	1915352	Expression and characterization of protein kinase C-delta.

Q13618	CUL3_HUMAN	Cullin-3	10500095	Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells.

P15407	FOSL1_HUMAN	Fos-related antigen 1	8230424	Human T-cell leukemia virus type 1 Tax activates transcription of the human fra-1 gene through multiple cis elements responsive to transmembrane signals.

P47813	IF1AX_HUMAN	Eukaryotic translation initiation factor 1A, X-chromosomal	8106356	Determination of the amino acid sequence of rabbit, human, and wheat germ protein synthesis factor eIF-4C by cloning and chemical sequencing.

Q96247	AUX1_ARATH	Auxin transporter protein 1	8688077	Arabidopsis AUX1 gene: a permease-like regulator of root gravitropism.

Q9ULX6	AKP8L_HUMAN	A-kinase anchor protein 8-like	18313049	A cancer-associated RING finger protein, RNF43, is a ubiquitin ligase that interacts with a nuclear protein, HAP95.

Q9HFE7	YNW5_SCHPO	Ankyrin repeat-containing protein P16F5.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8AXX2	TBX1_DANRE	T-box transcription factor TBX1	12952905	The zebrafish van gogh mutation disrupts tbx1, which is involved in the DiGeorge deletion syndrome in humans.

P61088	UBE2N_HUMAN	Ubiquitin-conjugating enzyme E2 N	10089880	Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair.

Q9BZW7	TSG10_HUMAN	Testis-specific gene 10 protein	11179690	Identification and characterisation of a novel gene, TSGA10, expressed in testis.

P82706	IM01_DROME	Immune-induced peptide 1	9736738	Differential display of peptides induced during the immune response of Drosophila: a matrix-assisted laser desorption ionization time-of- flight mass spectrometry study.

P51830	ADCY9_MOUSE	Adenylate cyclase type 9	7575502	Control of a novel adenylyl cyclase by calcineurin.

Q9Y261	FOXA2_HUMAN	Hepatocyte nuclear factor 3-beta	15737987	A hepatocyte nuclear factor-3 site in the fibrinogen beta promoter is important for interleukin 6-induced expression, and its activity is influenced by the adjacent -148C/T polymorphism.

O43019	SRE2_SCHPO	Putative transcription factor sre2	11790253	Computational prediction of membrane-tethered transcription factors.

P52740	ZN132_HUMAN	Zinc finger protein 132	7557990	Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders.

Q14457	BECN1_HUMAN	Beclin-1	19270696	Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages.

O08811	ERCC2_MOUSE	TFIIH basal transcription factor complex helicase XPD subunit	9426063	Disruption of the mouse xeroderma pigmentosum group D DNA repair/basal transcription gene results in preimplantation lethality.

Q05BQ1	TUTLA_MOUSE	Protein turtle homolog A	15340157	Control of dendrite arborization by an Ig family member, dendrite arborization and synapse maturation 1 (Dasm1).

O00757	F16P2_HUMAN	Fructose-1,6-bisphosphatase isozyme 2	9678974	Isolation and characterization of an allelic cDNA for human muscle fructose-1,6-bisphosphatase.

P24004	PEX1_YEAST	Peroxisomal ATPase PEX1	15634331	Structural and functional analysis of the interaction of the AAA- peroxins Pex1p and Pex6p.

Q06668	OMS1_YEAST	Methyltransferase OMS1, mitochondrial	15355998	A yeast mitochondrial membrane methyltransferase-like protein can compensate for oxa1 mutations.

O95704	APBB3_HUMAN	Amyloid beta A4 precursor protein-binding family B member 3	10081969	Molecular cloning of human Fe65L2 and its interaction with the Alzheimer's beta-amyloid precursor protein.

Q9C0U3	MU153_SCHPO	Meiotically up-regulated gene 153 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q6UWL6	KIRR2_HUMAN	Kin of IRRE-like protein 2	12837264	Kirrel2, a novel immunoglobulin superfamily gene expressed primarily in beta cells of the pancreatic islets.

Q3MV19	TRF6A_XENLA	TNF receptor-associated factor 6-A	16023795	Identification and characterization of Xenopus laevis homologs of mammalian TRAF6 and its binding protein TIFA.

Q9M2Y6	Y3972_ARATH	Uncharacterized protein At3g49720	16618929	Mapping the Arabidopsis organelle proteome.

Q9QXM1	JMY_MOUSE	Junction-mediating and -regulatory protein	10518217	A novel cofactor for p300 that regulates the p53 response.

Q9BWV1	BOC_HUMAN	Brother of CDO	11782431	BOC, an Ig superfamily member, associates with CDO to positively regulate myogenic differentiation.

Q08484	GYP1_YEAST	GTPase-activating protein GYP1	11359917	Yeast rab GTPase-activating protein Gyp1p localizes to the Golgi apparatus and is a negative regulator of Ypt1p.

P75780	FIU_ECOLI	Catecholate siderophore receptor fiu	2407721	Cir and Fiu proteins in the outer membrane of Escherichia coli catalyze transport of monomeric catechols: study with beta-lactam antibiotics containing catechol and analogous groups.

Q9UNP9	PPIE_HUMAN	Peptidyl-prolyl cis-trans isomerase E	9747881	Co-amplification of a novel cyclophilin-like gene (PPIE) with L-myc in small cell lung cancer cell lines.

Q00055	GPD1_YEAST	Glycerol-3-phosphate dehydrogenase [NAD+] 1	8196651	GPD1, which encodes glycerol-3-phosphate dehydrogenase, is essential for growth under osmotic stress in Saccharomyces cerevisiae, and its expression is regulated by the high-osmolarity glycerol response pathway.

P21663	ANDP_DROME	Andropin	1899226	The andropin gene and its product, a male-specific antibacterial peptide in Drosophila melanogaster.

Q9UKX5	ITA11_HUMAN	Integrin alpha-11	10486209	Cloning, sequence analysis, and chromosomal localization of the novel human integrin alpha11 subunit (ITGA11).

Q96HR8	NAF1_HUMAN	H/ACA ribonucleoprotein complex non-core subunit NAF1	17135485	Dynamic association and localization of human H/ACA RNP proteins.

O04138	CHI4_ORYSJ	Chitinase 4	12834284	Structure, heterologous expression, and properties of rice (Oryza sativa L.) family 19 chitinases.

Q5VSL9	FA40A_HUMAN	Protein FAM40A	15302935	Large-scale characterization of HeLa cell nuclear phosphoproteins.

Q15365	PCBP1_HUMAN	Poly(rC)-binding protein 1	7556077	Identification of two KH domain proteins in the alpha-globin mRNP stability complex.

O74963	NCA2_SCHPO	Nuclear control of ATPase protein 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P40164	PP4R3_YEAST	Serine/threonine-protein phosphatase 4 regulatory subunit 3	14562095	Global analysis of protein localization in budding yeast.

Q1JQ73	ELV1A_XENLA	ELAV-like protein 1-A	16930598	Xenopus ElrB, but not ElrA, binds RNA as an oligomer: possible role of the linker.

P23396	RS3_HUMAN	40S ribosomal protein S3	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

Q12946	FOXF1_HUMAN	Forkhead box protein F1	9769171	FREAC-1 contains a cell-type-specific transcriptional activation domain and is expressed in epithelial-mesenchymal interfaces.

P51175	PPOX_MOUSE	Protoporphyrinogen oxidase	3346226	Organization of the terminal two enzymes of the heme biosynthetic pathway. Orientation of protoporphyrinogen oxidase and evidence for a membrane complex.

Q94547	RGA_DROME	Regulator of gene activity	9475742	Regena (Rga), a Drosophila homolog of the global negative transcriptional regulator CDC36 (NOT2) from yeast, modifies gene expression and suppresses position effect variegation.

Q8N9I0	SYT2_HUMAN	Synaptotagmin-2	19234194	Human SCAMP5, a novel secretory carrier membrane protein, facilitates calcium-triggered cytokine secretion by interaction with SNARE machinery.

O42839	APC4_SCHPO	Anaphase-promoting complex subunit 4	10082519	The Schizosaccharomyces pombe dim1(+) gene interacts with the anaphase-promoting complex or cyclosome (APC/C) component lid1(+) and is required for APC/C function.

Q23175	HM32_CAEEL	Homeobox protein ceh-32	11476572	The Caenorhabditis elegans Six/sine oculis class homeobox gene ceh-32 is required for head morphogenesis.

Q08446	SGT1_YEAST	Protein SGT1	12456005	Sgt1p contributes to cyclic AMP pathway activity and physically interacts with the adenylyl cyclase Cyr1p/Cdc35p in budding yeast.

P16501	IGF1A_XENLA	Insulin-like growth factor I-A	11709186	Neural and head induction by insulin-like growth factor signals.

Q32MG2	SPERT_MOUSE	Spermatid-associated protein	12204287	Nurit, a novel leucine-zipper protein, expressed uniquely in the spermatid flower-like structure.

Q9UKV0	HDAC9_HUMAN	Histone deacetylase 9	12590135	The histone deacetylase 9 gene encodes multiple protein isoforms.

O35786	CML1_RAT	Chemokine-like receptor 1	9425281	Molecular cloning and tissue distribution of cDNA encoding a novel chemoattractant-like receptor.

Q9Y5I1	PCDAB_HUMAN	Protocadherin alpha-11	10380929	A striking organization of a large family of human neural cadherin- like cell adhesion genes.

Q99717	SMAD5_HUMAN	Mothers against decapentaplegic homolog 5	10708948	The Smad pathway.

Q960V3	MILT_DROME	Trafficking kinesin-binding protein milt	16887820	Milton controls the early acquisition of mitochondria by Drosophila oocytes.

Q7T3L1	KNL1A_BOMMX	Kininogen-1a	12668203	Bombinakinin M gene associated peptide, a novel bioactive peptide from skin secretions of the toad Bombina maxima.

Q03569	GPR2_CAEEL	G-protein regulator 2	12730122	A complex of LIN-5 and GPR proteins regulates G protein signaling and spindle function in C elegans.

Q9V7Y2	SGPL_DROME	Sphingosine-1-phosphate lyase	12702658	Sply regulation of sphingolipid signaling molecules is essential for Drosophila development.

P79920	NDF4_XENLA	Neurogenic differentiation factor 4	15531363	Sequences downstream of the bHLH domain of the Xenopus hairy-related transcription factor-1 act as an extended dimerization domain that contributes to the selection of the partners.

Q9NS39	RED2_HUMAN	Double-stranded RNA-specific editase B2	10836796	A third member of the RNA-specific adenosine deaminase gene family, ADAR3, contains both single- and double-stranded RNA binding domains.

Q09137	AAPK2_RAT	5'-AMP-activated protein kinase catalytic subunit alpha-2	14511394	Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade.

P12035	K2C3_HUMAN	Keratin, type II cytoskeletal 3	9171831	Mutations in cornea-specific keratin K3 or K12 genes cause Meesmann's corneal dystrophy.

Q7TMF2	ERI1_MOUSE	3'-5' exoribonuclease 1	18438418	Mouse Eri1 interacts with the ribosome and catalyzes 5.8S rRNA processing.

P45973	CBX5_HUMAN	Chromobox protein homolog 5	19783980	JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatin.

P13073	COX41_HUMAN	Cytochrome c oxidase subunit 4 isoform 1, mitochondrial	2157630	Novel use of a chimpanzee pseudogene for chromosomal mapping of human cytochrome c oxidase subunit IV.

O01367	HOW_DROME	Protein held out wings	9332381	A Drosophila muscle-specific gene related to the mouse quaking locus.

Q8K2C8	GPAT4_MOUSE	Glycerol-3-phosphate acyltransferase 4	18238778	AGPAT6 is a novel microsomal glycerol-3-phosphate acyltransferase.

Q9Y817	RAV1_SCHPO	Putative regulator of V-ATPase in vacuolar membrane protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P50229	CCL3_RAT	C-C motif chemokine 3	7722328	Role of macrophage inflammatory protein-1 alpha (MIP-1 alpha) in acute lung injury in rats.

P38123	SWD3_YEAST	COMPASS component SWD3	11805083	COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression.

Q9FGL2	TIP23_ARATH	Aquaporin TIP2-3	15665250	Tonoplast intrinsic proteins AtTIP2;1 and AtTIP2;3 facilitate NH3 transport into the vacuole.

O74986	COM1_SCHPO	DNA endonuclease ctp1	17936710	Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination.

Q75K24	CSN8_DICDI	COP9 signalosome complex subunit 8	16781008	The COP9 signalosome regulates cell proliferation of Dictyostelium discoideum.

Q04721	NOTC2_HUMAN	Neurogenic locus notch homolog protein 2	11101851	MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors.

Q01955	CO4A3_HUMAN	Collagen alpha-3(IV) chain	10766752	Distinct antitumor properties of a type IV collagen domain derived from basement membrane.

P41222	PTGDS_HUMAN	Prostaglandin-H2 D-isomerase	9065498	Prostaglandin D synthase (beta-trace) in human arachnoid and meningioma cells: roles as a cell marker or in cerebrospinal fluid absorption, tumorigenesis, and calcification process.

Q9UBB5	MBD2_HUMAN	Methyl-CpG-binding domain protein 2	11553631	Involvement of a novel zinc finger protein, MIZF, in transcriptional repression by interacting with a methyl-CpG-binding protein, MBD2.

Q02878	RL6_HUMAN	60S ribosomal protein L6	8479925	Sequence of a cDNA encoding human ribosomal protein L26 and of a cDNA probably encoding human ribosomal protein L6.

Q07998	BRACA_DANRE	Brachyury protein homolog A	17717538	Light-controlled gene silencing in zebrafish embryos.

P48439	OST3_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3	16297388	Yeast oligosaccharyltransferase consists of two functionally distinct sub-complexes, specified by either the Ost3p or Ost6p subunit.

Q01638	ILRL1_HUMAN	Interleukin-1 receptor-like 1	16286016	IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST 2 and induces T helper type 2-associated cytokines.

Q17381	PHA4_CAEEL	Defective pharyngeal development protein 4	7607089	The pha-4 gene is required to generate the pharyngeal primordium of Caenorhabditis elegans.

O15047	SET1A_HUMAN	Histone-lysine N-methyltransferase SETD1A	12670868	Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell- proliferation factor HCF-1.

Q63315	CAD22_RAT	Cadherin-22	8626716	Molecular cloning and characterization of a newly identified member of the cadherin family, PB-cadherin.

P38212	RCR1_YEAST	Protein RCR1	17213653	Peculiar protein-protein interactions of the novel endoplasmic reticulum membrane protein Rcr1 and ubiquitin ligase Rsp5.

P98194	AT2C1_HUMAN	Calcium-transporting ATPase type 2C member 1	12707275	Effect of Hailey-Hailey Disease mutations on the function of a new variant of human secretory pathway Ca2+/Mn2+-ATPase (hSPCA1).

Q16763	UBE2S_HUMAN	Ubiquitin-conjugating enzyme E2 S	1379239	cDNA cloning of a novel human ubiquitin carrier protein. An antigenic domain specifically recognized by endemic pemphigus foliaceus autoantibodies is encoded in a secondary reading frame of this human epidermal transcript.

P32580	SUV3_YEAST	ATP-dependent RNA helicase SUV3, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

O13945	PPK9_SCHPO	Protein kinase domain-containing protein ppk9	15821139	Systematic deletion analysis of fission yeast protein kinases.

Q99217	AMELX_HUMAN	Amelogenin, X isoform	2509010	Human amelogenins: sequences of 'TRAP' molecules.

Q62315	JARD2_MOUSE	Protein Jumonji	15542826	Jumonji represses atrial natriuretic factor gene expression by inhibiting transcriptional activities of cardiac transcription factors.

P0A7E3	PYRE_ECOLI	Orotate phosphoribosyltransferase	8620002	A flexible loop at the dimer interface is a part of the active site of the adjacent monomer of Escherichia coli orotate phosphoribosyltransferase.

Q9NRR1	CYTL1_HUMAN	Cytokine-like protein 1	10857752	Molecular cloning and chromosomal mapping of a candidate cytokine gene selectively expressed in human CD34+ cells.

Q9NYZ3	GTSE1_HUMAN	G2 and S phase-expressed protein 1	10974554	Cloning, chromosome mapping and functional characterization of a human homologue of murine Gtse-1 (B99) gene.

Q7Z419	R144B_HUMAN	E3 ubiquitin-protein ligase RNF144B	12853982	p53RFP, a p53-inducible RING-finger protein, regulates the stability of p21WAF1.

Q15042	RB3GP_HUMAN	Rab3 GTPase-activating protein catalytic subunit	10859313	Biochemical characterization of Rab3-GTPase-activating protein reveals a mechanism similar to that of Ras-GAP.

Q9D0K1	PEX13_MOUSE	Peroxisomal membrane protein PEX13	11829486	Pex13, the mouse ortholog of the human peroxisome biogenesis disorder PEX13 gene: gene structure, tissue expression, and localization of the protein to peroxisomes.

Q9UL45	PLDN_HUMAN	Pallidin	10610180	The pallid gene encodes a novel, syntaxin 13-interacting protein involved in platelet storage pool deficiency.

P0C1X8	AAK1_RAT	AP2-associated protein kinase 1	11877461	Identification of an adaptor-associated kinase, AAK1, as a regulator of clathrin-mediated endocytosis.

Q07439	HSP71_RAT	Heat shock 70 kDa protein 1A/1B	8271311	cDNA cloning and expression of stress-inducible rat hsp70 in normal and injured rat brain.

O43739	CYH3_HUMAN	Cytohesin-3	9707577	ARNO3, a Sec7-domain guanine nucleotide exchange factor for ADP ribosylation factor 1, is involved in the control of Golgi structure and function.

Q95PI2	DHKC_DICDI	Hybrid signal transduction histidine kinase C	9808785	The histidine kinase dhkC regulates the choice between migrating slugs and terminal differentiation in Dictyostelium discoideum.

Q9LSE2	ICE1_ARATH	Transcription factor ICE1	18641265	SCREAM/ICE1 and SCREAM2 specify three cell-state transitional steps leading to arabidopsis stomatal differentiation.

P97465	DOK1_MOUSE	Docking protein 1	9008161	Identification of the Abl- and rasGAP-associated 62 kDa protein as a docking protein, Dok.

Q9UNH7	SNX6_HUMAN	Sorting nexin-6	11279102	Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases.

Q8IU54	IL29_HUMAN	Interleukin-29	12469119	IL-28, IL-29 and their class II cytokine receptor IL-28R.

O15121	DEGS1_HUMAN	Sphingolipid delta(4)-desaturase DES1	9188692	The product of the MLD gene is a member of the membrane fatty acid desaturase family: overexpression of MLD inhibits EGF receptor biosynthesis.

P46734	MP2K3_HUMAN	Dual specificity mitogen-activated protein kinase kinase 3	11980910	Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha.

Q62418	DBNL_MOUSE	Drebrin-like protein	10637315	Association of mouse actin-binding protein 1 (mAbp1/SH3P7), an Src kinase target, with dynamic regions of the cortical actin cytoskeleton in response to Rac1 activation.

P86094	NXS11_MICSU	Short neurotoxin MS11	18384102	Proteomic analysis of the venom from the fish eating coral snake Micrurus surinamensis: novel toxins, their function and phylogeny.

P42837	FIG4_YEAST	Polyphosphoinositide phosphatase	11950935	Regulation of Fab1 phosphatidylinositol 3-phosphate 5-kinase pathway by Vac7 protein and Fig4, a polyphosphoinositide phosphatase family member.

P16591	FER_HUMAN	Tyrosine-protein kinase Fer	2725517	Isolation and sequence analysis of a novel human tyrosine kinase gene.

P38862	ATG7_YEAST	Ubiquitin-like modifier-activating enzyme ATG7	10233150	Apg7p/Cvt2p: a novel protein-activating enzyme essential for autophagy.

P47124	HOC1_YEAST	Putative glycosyltransferase HOC1	9430634	Multi-protein complexes in the cis Golgi of Saccharomyces cerevisiae with alpha-1,6-mannosyltransferase activity.

P23776	EXG1_YEAST	Glucan 1,3-beta-glucosidase I/II	9748433	New potential cell wall glucanases of Saccharomyces cerevisiae and their involvement in mating.

P34127	MYBA_DICDI	Myb-like protein A	1549373	The Myb DNA-binding domain is highly conserved in Dictyostelium discoideum.

O08569	ZP3R_CAVPO	Zona pellucida sperm-binding protein 3 receptor	9139729	AM67, a secretory component of the guinea pig sperm acrosomal matrix, is related to mouse sperm protein sp56 and the complement component 4- binding proteins.

O60447	EVI5_HUMAN	Ecotropic viral integration site 5 protein homolog	9618176	NB4S, a member of the TBC1 domain family of genes, is truncated as a result of a constitutional t(1;10)(p22;q21) chromosome translocation in a patient with stage 4S neuroblastoma.

Q10281	GBLP_SCHPO	Guanine nucleotide-binding protein subunit beta-like protein	11263963	Rkp1/Cpc2, a fission yeast RACK1 homolog, is involved in actin cytoskeleton organization through protein kinase C, Pck2, signaling.

O60258	FGF17_HUMAN	Fibroblast growth factor 17	9514906	Structure and expression of a novel fibroblast growth factor, FGF-17, preferentially expressed in the embryonic brain.

Q4V8B0	OXR1_RAT	Oxidation resistance protein 1	11237729	C7, a novel nucleolar protein, is the mouse homologue of the Drosophila late puff product L82 and an isoform of human OXR1.

P08459	SPS2_YEAST	Sporulation-specific protein 2	3023934	Characterization and mutational analysis of a cluster of three genes expressed preferentially during sporulation of Saccharomyces cerevisiae.

P46668	ATHB6_ARATH	Homeobox-leucine zipper protein ATHB-6	10527431	The HD-Zip gene ATHB6 in Arabidopsis is expressed in developing leaves, roots and carpels and up-regulated by water deficit conditions.

Q8WWN8	ARAP3_HUMAN	Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3	11804589	Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices.

Q1PE39	MRS26_ARATH	Magnesium transporter MRS2-6, mitochondrial	19825572	A mitochondrial magnesium transporter functions in Arabidopsis pollen development.

P0A742	MSCL_ECOLI	Large-conductance mechanosensitive channel	10202137	Protection of Escherichia coli cells against extreme turgor by activation of MscS and MscL mechanosensitive channels: identification of genes required for MscS activity.

Q08850	STX4_RAT	Syntaxin-4	14993220	Identification of SNAREs involved in synaptotagmin VII-regulated lysosomal exocytosis.

Q9Z2C8	YBOX2_MOUSE	Y-box-binding protein 2	12297523	RNA-binding properties and translation repression in vitro by germ cell-specific MSY2 protein.

O43663	PRC1_HUMAN	Protein regulator of cytokinesis 1	9885575	PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis.

Q9NS56	TOPRS_HUMAN	E3 ubiquitin-protein ligase Topors	20188669	SUMOylation-dependent localization of IKKepsilon in PML nuclear bodies is essential for protection against DNA-damage-triggered cell death.

Q64611	CSAD_RAT	Cysteine sulfinic acid decarboxylase	7772604	Cloning and characterization of rat cysteine sulfinic acid decarboxylase.

Q8H1S0	MIOX4_ARATH	Inositol oxygenase 4	14976233	Myo-inositol oxygenase offers a possible entry point into plant ascorbate biosynthesis.

P48415	SEC16_YEAST	COPII coat assembly protein SEC16	12235121	Sec16p potentiates the action of COPII proteins to bud transport vesicles.

Q9V3W6	INX7_DROME	Innexin inx7	10352230	Drosophila has several genes for gap junction proteins.

Q96F07	CYFP2_HUMAN	Cytoplasmic FMR1-interacting protein 2	10449408	Increased apoptosis induction by 121F mutant p53.

Q91ZW2	OFUT1_MOUSE	GDP-fucose protein O-fucosyltransferase 1	11524432	Modification of epidermal growth factor-like repeats with O-fucose: molecular cloning and expression of a novel GDP-fucose protein O- fucosyltransferase.

Q9HC77	CENPJ_HUMAN	Centromere protein J	15047868	Identification of a novel microtubule-destabilizing motif in CPAP that binds to tubulin heterodimers and inhibits microtubule assembly.

P07910	HNRPC_HUMAN	Heterogeneous nuclear ribonucleoproteins C1/C2	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

Q9S3R9	OMP41_PORGI	Outer membrane protein 41	11532011	Identification of a novel heterodimeric outer membrane protein of Porphyromonas gingivalis by two-dimensional gel electrophoresis and peptide mass fingerprinting.

P19524	MYO2_YEAST	Myosin-2	8294515	The unconventional myosin, Myo2p, is a calmodulin target at sites of cell growth in Saccharomyces cerevisiae.

P47881	OR3A1_HUMAN	Olfactory receptor 3A1	8921386	Sequence analysis in the olfactory receptor gene cluster on human chromosome 17: recombinatorial events affecting receptor diversity.

P35131	UBC8_ARATH	Ubiquitin-conjugating enzyme E2 8	12028569	Biochemical evidence for ubiquitin ligase activity of the Arabidopsis COP1 interacting protein 8 (CIP8).

P36077	SRX1_YEAST	Sulfiredoxin	14562095	Global analysis of protein localization in budding yeast.

Q80VW5	WHRN_MOUSE	Whirlin	16829577	Whirlin complexes with p55 at the stereocilia tip during hair cell development.

P14922	CYC8_YEAST	General transcriptional corepressor CYC8	11069890	Ssn6-Tup1 interacts with class I histone deacetylases required for repression.

P14867	GBRA1_HUMAN	Gamma-aminobutyric acid receptor subunit alpha-1	2465923	Sequence and expression of human GABAA receptor alpha 1 and beta 1 subunits.

Q86YF9	DZIP1_HUMAN	Zinc finger protein DZIP1	15081113	Identification of a novel gene, DZIP (DAZ-interacting protein), that encodes a protein that interacts with DAZ (deleted in azoospermia) and is expressed in embryonic stem cells and germ cells.

P53206	CYSK_YEAST	Putative cysteine synthase	9290212	Sequence analysis of 203 kilobases from Saccharomyces cerevisiae chromosome VII.

Q04637	IF4G1_HUMAN	Eukaryotic translation initiation factor 4 gamma 1	8961935	A single amino acid change in protein synthesis initiation factor 4G renders cap-dependent translation resistant to picornaviral 2A proteases.

Q54ER9	DIMB_DICDI	Basic-leucine zipper transcription factor B	16396914	The Dictyostelium bZIP transcription factor DimB regulates prestalk- specific gene expression.

Q14160	SCRIB_HUMAN	Protein scribble homolog	19555689	MCC, a new interacting protein for Scrib, is required for cell migration in epithelial cells.

P0A9Q5	ACCD_ECOLI	Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta	16460018	The structure of the carboxyltransferase component of acetyl-coA carboxylase reveals a zinc-binding motif unique to the bacterial enzyme.

P58959	G39AD_DROME	Putative gustatory receptor 39a, isoform A	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

Q14195	DPYL3_HUMAN	Dihydropyrimidinase-related protein 3	9115293	Identification and characterization of a retinoic acid-regulated human homologue of the unc-33-like phosphoprotein gene (hUlip) from neuroblastoma cells.

P38348	HSM3_YEAST	DNA mismatch repair protein HSM3	10681183	The yeast HSM3 gene is involved in DNA mismatch repair in slowly dividing cells.

Q96JB2	COG3_HUMAN	Conserved oligomeric Golgi complex subunit 3	11929878	Sec34 is implicated in traffic from the endoplasmic reticulum to the Golgi and exists in a complex with GTC-90 and ldlBp.

Q9VN41	SLX1_DROME	Structure-specific endonuclease subunit SLX1 homolog	19595722	Drosophila MUS312 and the vertebrate ortholog BTBD12 interact with DNA structure-specific endonucleases in DNA repair and recombination.

Q9SYM4	TPS1_ARATH	Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 1	11520870	Trehalose metabolism in Arabidopsis: occurrence of trehalose and molecular cloning and characterization of trehalose-6-phosphate synthase homologues.

Q9USV4	MEP33_SCHPO	mRNA export protein 33	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q2TB54	FCAMR_MOUSE	High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor	11062505	Fc alpha/mu receptor mediates endocytosis of IgM-coated microbes.

Q8R173	ZDHC3_MOUSE	Palmitoyltransferase ZDHHC3	15603741	Identification of PSD-95 palmitoylating enzymes.

P05318	RLA1_YEAST	60S acidic ribosomal protein P1-alpha	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

P22738	RL32_ARATH	60S ribosomal protein L3-2	2227432	Two evolutionarily divergent genes encode a cytoplasmic ribosomal protein of Arabidopsis thaliana.

P97586	CGRE1_RAT	Cell growth regulator with EF hand domain protein 1	8968090	Induction of cell growth regulatory genes by p53.

Q9W367	GR08A_DROME	Putative gustatory receptor 8a	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

Q09767	ARL_SCHPO	ADP-ribosylation factor-like protein alp41	10683446	A conserved small GTP-binding protein Alp41 is essential for the cofactor-dependent biogenesis of microtubules in fission yeast.

P42745	UBC2_ARATH	Ubiquitin-conjugating enzyme E2 2	16339806	Genome analysis and functional characterization of the E2 and RING- type E3 ligase ubiquitination enzymes of Arabidopsis.

Q708S4	ACC4A_DANRE	Amiloride-sensitive cation channel 4-A	14970195	A family of acid-sensing ion channels (ASICs) from the zebrafish: widespread e xpression in the central nervous system suggests a conserved role in neuronal communication.

P08631	HCK_HUMAN	Tyrosine-protein kinase HCK	7791757	Myristoylation and differential palmitoylation of the HCK protein- tyrosine kinases govern their attachment to membranes and association with caveolae.

Q9P792	YN8B_SCHPO	ZZ-type zinc finger-containing protein P35G2.11c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P53550	DCP2_YEAST	mRNA-decapping enzyme subunit 2	10508173	The DCP2 protein is required for mRNA decapping in Saccharomyces cerevisiae and contains a functional MutT motif.

P46952	3HAO_HUMAN	3-hydroxyanthranilate 3,4-dioxygenase	7514594	Molecular cloning and functional expression of human 3- hydroxyanthranilic-acid dioxygenase.

Q10295	PAP_SCHPO	Poly(A) polymerase pla1	8692700	The Schizosaccharomyces pombe pla1 gene encodes a poly(A) polymerase and can functionally replace its Saccharomyces cerevisiae homologue.

O13370	DED1_SCHPO	ATP-dependent RNA helicase ded1	10725227	A fission yeast general translation factor reveals links between protein synthesis and cell cycle controls.

Q9VYB0	BTHD_DROME	Selenoprotein BthD	14612395	The Drosophila selenoprotein BthD is required for survival and has a role in salivary gland development.

Q9D2E1	TSSK3_MOUSE	Testis-specific serine/threonine-protein kinase 3	10781952	A novel member of the testis specific serine kinase family, tssk-3, expressed in the Leydig cells of sexually mature mice.

Q5MJ70	SPDYA_HUMAN	Speedy protein A	12839962	Human Spy1 promotes survival of mammalian cells following DNA damage.

Q9UL51	HCN2_HUMAN	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2	10228147	Two pacemaker channels from human heart with profoundly different activation kinetics.

P35201	MIF2_YEAST	Protein MIF2	8408221	MIF2 is required for mitotic spindle integrity during anaphase spindle elongation in Saccharomyces cerevisiae.

Q1AGV7	SDC4A_XENLA	Syndecan 4-A	17041718	xSyndecan-4 regulates gastrulation and neural tube closure in Xenopus embryos.

Q9NI63	PMYT1_DROME	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	11882391	Identification of Drosophila Myt1 kinase and its role in Golgi during mitosis.

Q09888	MU160_SCHPO	Meiotically up-regulated gene 160 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8NI51	CTCFL_HUMAN	Transcriptional repressor CTCFL	18413740	DNA methyltransferase 1 and 3B activate BAG-1 expression via recruitment of CTCFL/BORIS and modulation of promoter histone methylation.

P38828	LSM12_YEAST	Protein LSM12	16702403	Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes.

Q8R3H7	HS2ST_MOUSE	Heparan sulfate 2-O-sulfotransferase 1	11457822	The molecular phenotype of heparan sulfate in the Hs2st-/- mutant mouse.

Q9W7R5	SOX21_CHICK	Transcription factor SOX-21	10473124	Two distinct subgroups of Group B Sox genes for transcriptional activators and repressors: their expression during embryonic organogenesis of the chicken.

P84689	SC56_TITCA	Toxin Tc56	15025998	Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

P63345	ARC_MYCTU	Proteasome-associated ATPase	19448618	Bacterial ubiquitin-like modifier Pup is deamidated and conjugated to substrates by distinct but homologous enzymes.

Q00342	FLT3_MOUSE	FL cytokine receptor	10409713	Fiz1, a novel zinc finger protein interacting with the receptor tyrosine kinase Flt3.

P82252	BAT1_RAT	B(0,+)-type amino acid transporter 1	10506124	Identification of an amino acid transporter associated with the cystinuria-related type II membrane glycoprotein.

Q8BRU6	VMAT2_MOUSE	Synaptic vesicular amine transporter	19357284	Physical and functional interaction between the dopamine transporter and the synaptic vesicle protein synaptogyrin-3.

Q9Y0B7	PP4C_DICDI	Serine/threonine-protein phosphatase 4 catalytic subunit	17353263	MEK1 and protein phosphatase 4 coordinate Dictyostelium development and chemotaxis.

P54727	RD23B_HUMAN	UV excision repair protein RAD23 homolog B	15358861	A complex between peptide:N-glycanase and two proteasome-linked proteins suggests a mechanism for the degradation of misfolded glycoproteins.

Q9LKZ3	RBR1_ARATH	Retinoblastoma-related protein 1	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

O22881	POT2_ARATH	Potassium transporter 2	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q39083	DI191_ARATH	Protein DEHYDRATION-INDUCED 19	16438971	A novel yeast two-hybrid approach to identify CDPK substrates: characterization of the interaction between AtCPK11 and AtDi19, a nuclear zinc finger protein.

O43918	AIRE_HUMAN	Autoimmune regulator	18292755	The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression.

O74517	SAF1_SCHPO	Protein saf1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UL40	ZN346_HUMAN	Zinc finger protein 346	10488071	JAZ requires the double-stranded RNA-binding zinc finger motifs for nuclear localization.

P25208	NFYB_HUMAN	Nuclear transcription factor Y subunit beta	1577736	Intron-exon organization of the NF-Y genes. Tissue-specific splicing modifies an activation domain.

P51572	BAP31_HUMAN	B-cell receptor-associated protein 31	8706661	Molecular cloning and characterization of a transmembrane surface antigen in human cells.

Q8NCL4	GALT6_HUMAN	Polypeptide N-acetylgalactosaminyltransferase 6	10464263	Cloning and characterization of a close homologue of human UDP-N- acetyl--D-galactosamine:polypeptide N-acetylgalactosaminyltransferase- T3, designated GalNAc-T6. Evidence for genetic but not functional redundancy.

Q9SID1	STH_ARATH	Salt tolerance-like protein	11226162	Identification of a structural motif that confers specific interaction with the WD40 repeat domain of Arabidopsis COP1.

Q4KWH8	PLCH1_HUMAN	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta-1	15702972	Molecular cloning and characterization of a novel phospholipase C, PLC-eta.

Q8NEP3	LRC50_HUMAN	Leucine-rich repeat-containing protein 50	19944405	Loss-of-function mutations in the human ortholog of Chlamydomonas reinhardtii ODA7 disrupt dynein arm assembly and cause primary ciliary dyskinesia.

P48553	TPC10_HUMAN	Trafficking protein particle complex subunit 10	7633421	Isolation and characterization of a candidate gene for progressive myoclonus epilepsy on 21q22.3.

P84384	XT4_XENTR	Antimicrobial peptide 4	11738090	Antimicrobial peptides isolated from skin secretions of the diploid frog, Xenopus tropicalis (Pipidae).

Q8C172	LASS6_MOUSE	LAG1 longevity assurance homolog 6	15823095	Mammalian Lass6 and its related family members regulate synthesis of specific ceramides.

Q09028	RBBP4_HUMAN	Histone-binding protein RBBP4	8350924	A retinoblastoma-binding protein related to a negative regulator of Ras in yeast.

Q03308	VPS16_YEAST	Vacuolar protein sorting-associated protein 16	16601699	Purification of active HOPS complex reveals its affinities for phosphoinositides and the SNARE Vam7p.

O35437	TCF21_MOUSE	Transcription factor 21	10944221	The basic helix-loop-helix transcription factor capsulin controls spleen organogenesis.

P07900	HS90A_HUMAN	Heat shock protein HSP 90-alpha	9660753	Specific binding of tetratricopeptide repeat proteins to the C- terminal 12-kDa domain of hsp90.

P35206	CSG2_YEAST	Mannosyl phosphorylinositol ceramide synthase regulatory protein CSG2	7854312	The CLS2 gene encodes a protein with multiple membrane-spanning domains that is important Ca2+ tolerance in yeast.

P35187	SGS1_YEAST	ATP-dependent helicase SGS1	7736577	Sgs1: a eukaryotic homolog of E. coli RecQ that interacts with topoisomerase II in vivo and is required for faithful chromosome segregation.

Q08750	MUM3_YEAST	Protein MUM3	15590821	Morphogenetic pathway of spore wall assembly in Saccharomyces cerevisiae.

P55072	TERA_HUMAN	Transitional endoplasmic reticulum ATPase	16449189	Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation.

Q9UKI3	VPRE3_HUMAN	Pre-B lymphocyte protein 3	10702669	VPREB3: cDNA characterization and expression in human and chromosome mapping in human and mouse.

O35153	BET1L_MOUSE	BET1-like protein	9242691	GS15, a 15-kilodalton Golgi soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) homologous to rbet1.

Q9Z2A9	GGT5_MOUSE	Gamma-glutamyltransferase 5	9774450	Gamma-glutamyl leukotrienase, a gamma-glutamyl transpeptidase gene family member, is expressed primarily in spleen.

O48917	SQD1_ARATH	UDP-sulfoquinovose synthase, chloroplastic	9465123	Phosphate availability affects the thylakoid lipid composition and the expression of SQD1, a gene required for sulfolipid biosynthesis in Arabidopsis thaliana.

P48565	PALH_YEAST	pH-response regulator protein palH/RIM21	10821185	Ambient pH signalling in ascomycetous yeasts involves homologues of the Aspergillus nidulans genes palF and palH.

Q8VHN7	GPR98_MOUSE	G-protein coupled receptor 98	11545713	A novel gene causing a mendelian audiogenic mouse epilepsy.

Q60770	STXB3_MOUSE	Syntaxin-binding protein 3	17548353	Doc2beta is a novel Munc18c-interacting partner and positive effector of syntaxin 4-mediated exocytosis.

O24646	HY5_ARATH	Transcription factor HY5	9367981	The Arabidopsis HY5 gene encodes a bZIP protein that regulates stimulus-induced development of root and hypocotyl.

Q93W20	NIFU2_ARATH	NifU-like protein 2, chloroplastic	15031412	The Arabidopsis chloroplastic NifU-like protein CnfU, which can act as an iron-sulfur cluster scaffold protein, is required for biogenesis of ferredoxin and photosystem I.

P32119	PRDX2_HUMAN	Peroxiredoxin-2	8144038	The thiol-specific antioxidant protein from human brain: gene cloning and analysis of conserved cysteine regions.

O43090	NDH2_SCHPO	Probable NADH-ubiquinone oxidoreductase C947.15c, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8K4I4	PLUNC_RAT	Protein Plunc	11821380	Plunc, a member of the secretory gland protein family, is up- regulated in nasal respiratory epithelium after olfactory bulbectomy.

P11868	TDCD_ECOLI	Propionate kinase	9484901	Novel keto acid formate-lyase and propionate kinase enzymes are components of an anaerobic pathway in Escherichia coli that degrades L-threonine to propionate.

O88466	ZF106_MOUSE	Zinc finger protein 106	9507006	Identification of sirm, a novel insulin-regulated SH3 binding protein that associates with Grb-2 and FYN.

P35734	ASK1_YEAST	DASH complex subunit ASK1	11799062	The mitotic spindle is required for loading of the DASH complex onto the kinetochore.

Q9NRR2	TRYG1_HUMAN	Tryptase gamma	10521469	Identification of a new member of the tryptase family of mouse and human mast cell proteases which possesses a novel COOH-terminal hydrophobic extension.

Q9QXU9	PCSK1_RAT	ProSAAS	10632593	Identification and characterization of proSAAS, a granin-like neuroendocrine peptide precursor that inhibits prohormone processing.

P53124	PCL10_YEAST	PHO85 cyclin-10	9584169	Cyclin partners determine Pho85 protein kinase substrate specificity in vitro and in vivo: control of glycogen biosynthesis by Pcl8 and Pcl10.

Q39255	SKP1A_ARATH	SKP1-like protein 1A	19682297	An F-box gene, CPR30, functions as a negative regulator of the defense response in Arabidopsis.

O15270	SPTC2_HUMAN	Serine palmitoyltransferase 2	9363775	Human and murine serine-palmitoyl-CoA transferase. Cloning, expression and characterization of the key enzyme in sphingolipid synthesis.

P61978	HNRPK_HUMAN	Heterogeneous nuclear ribonucleoprotein K	1729596	Characterization and primary structure of the poly(C)-binding heterogeneous nuclear ribonucleoprotein complex K protein.

P53125	ITC1_YEAST	Imitation switch two complex protein 1	12624196	Cell-type-dependent repression of yeast a-specific genes requires Itc1p, a subunit of the Isw2p-Itc1p chromatin remodelling complex.

Q9C6M5	RAVL1_ARATH	AP2/ERF and B3 domain-containing transcription repressor TEM1	18718758	The balance between CONSTANS and TEMPRANILLO activities determines FT expression to trigger flowering.

P00559	PGK1_HORSE	Phosphoglycerate kinase 1	450128	Sequence, structure and activity of phosphoglycerate kinase: a possible hinge-bending enzyme.

P25859	CKB11_ARATH	Cyclin-dependent kinase B1-1	10521519	An Arabidopsis cell cycle-dependent kinase-related gene, CDC2b, plays a role in regulating seedling growth in darkness.

P10862	RAD18_YEAST	Postreplication repair E3 ubiquitin-protein ligase RAD18	9287349	Yeast DNA repair proteins Rad6 and Rad18 form a heterodimer that has ubiquitin conjugating, DNA binding, and ATP hydrolytic activities.

Q53EK2	NSE1_SCHPO	Non-structural maintenance of chromosomes element 1	12966087	Novel essential DNA repair proteins Nse1 and Nse2 are subunits of the fission yeast Smc5-Smc6 complex.

O42913	NRM1_SCHPO	Transcription factor nrm1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P40957	MAD1_YEAST	Spindle assembly checkpoint component MAD1	10837255	Complex formation between Mad1p, Bub1p and Bub3p is crucial for spindle checkpoint function.

Q8W1L6	MFP_ORYSJ	Peroxisomal fatty acid beta-oxidation multifunctional protein	11706039	Identification of a rice RNA- and microtubule-binding protein as the multifunctional protein, a peroxisomal enzyme involved in the beta- oxidation of fatty acids.

Q9TXD9	CUF1_TENMO	Larval cuticle protein F1	7795523	Isoforms of a cuticular protein from larvae of the meal beetle, Tenebrio molitor, studied by mass spectrometry in combination with Edman degradation and two-dimensional polyacrylamide gel electrophoresis.

Q9DBU5	RNF6_MOUSE	E3 ubiquitin-protein ligase RNF6	11971979	Gene control in germinal differentiation: RNF6, a transcription regulatory protein in the mouse sertoli cell.

Q76EJ3	S35D2_HUMAN	UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter	9927678	Three proteins involved in Caenorhabditis elegans vulval invagination are similar to components of a glycosylation pathway.

P11498	PYC_HUMAN	Pyruvate carboxylase, mitochondrial	7918683	Primary amino acid sequence and structure of human pyruvate carboxylase.

Q9W3C7	PPT1_DROME	Palmitoyl-protein thioesterase 1	16452138	Palmitoyl-protein thioesterase 1 deficiency in Drosophila melanogaster causes accumulation of abnormal storage material and reduced life span.

O43913	ORC5_HUMAN	Origin recognition complex subunit 5	9765232	ORC5L, a new member of the human origin recognition complex, is deleted in uterine leiomyomas and malignant myeloid diseases.

Q7Z2E3	APTX_HUMAN	Aprataxin	16964241	The neurodegenerative disease protein aprataxin resolves abortive DNA ligation intermediates.

Q13445	TMED1_HUMAN	Transmembrane emp24 domain-containing protein 1	8621446	Cloning of a putative ligand for the T1/ST2 receptor.

Q10135	LSD2_SCHPO	Lysine-specific histone demethylase 2	16990277	Fission yeast homologs of human histone H3 lysine 4 demethylase regulate a common set of genes with diverse functions.

Q9H8P0	PORED_HUMAN	Probable polyprenol reductase	17986282	Novel 5 alpha-steroid reductase (SRD5A3, type-3) is overexpressed in hormone-refractory prostate cancer.

Q63147	HEM0_RAT	5-aminolevulinate synthase, erythroid-specific, mitochondrial	8407861	Purification and structure of rat erythroid-specific delta- aminolevulinate synthase.

O00462	MANBA_HUMAN	Beta-mannosidase	9384606	Human beta-mannosidase cDNA characterization and first identification of a mutation associated with human beta-mannosidosis.

P04921	GLPC_HUMAN	Glycophorin-C	8219208	A point mutation in the GYPC gene results in the expression of the blood group Ana antigen on glycophorin D but not on glycophorin C: further evidence that glycophorin D is a product of the GYPC gene.

Q10746	CXCL3_RAT	C-X-C motif chemokine 3	8043001	Identification of cytokine-induced neutrophil chemoattractants (CINC), rat GRO/CINC-2 alpha and CINC-2 beta, produced by granulation tissue in culture: purification, complete amino acid sequences and characterization.

Q5BDU5	EGLA_EMENI	Endo-beta-1,4-glucanase A	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

Q61301	CTNA2_MOUSE	Catenin alpha-2	16691566	Alpha N-catenin deficiency causes defects in axon migration and nuclear organization in restricted regions of the mouse brain.

Q9P7P2	HOP1_SCHPO	Meiosis-specific protein hop1	15226405	S. pombe meiotic linear elements contain proteins related to synaptonemal complex components.

O80536	PIF3_ARATH	Transcription factor PIF3	12897250	The Arabidopsis basic/helix-loop-helix transcription factor family.

P32914	SPT4_YEAST	Transcription elongation factor SPT4	8649393	Faithful chromosome transmission requires Spt4p, a putative regulator of chromatin structure in Saccharomyces cerevisiae.

O75093	SLIT1_HUMAN	Slit homolog 1 protein	9813312	Cloning and expressions of three mammalian homologues of Drosophila slit suggest possible roles for Slit in the formation and maintenance of the nervous system.

Q9ZT82	CALSC_ARATH	Callose synthase 12	16021399	Two callose synthases, GSL1 and GSL5, play an essential and redundant role in plant and pollen development and in fertility.

Q923D5	WBP11_MOUSE	WW domain-binding protein 11	14640981	SIPP1, a novel pre-mRNA splicing factor and interactor of protein phosphatase-1.

Q9I8A3	HEY1_XENLA	Hairy/enhancer-of-split related with YRPW motif protein 1	15451171	Transcriptional repression by the bHLH-Orange factor XHRT1 does not involve the C-terminal YRPW motif.

Q9UT77	GATB_SCHPO	Probable glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q148W0	AT8B1_MOUSE	Probable phospholipid-transporting ATPase IC	14976163	A mouse genetic model for familial cholestasis caused by ATP8B1 mutations reveals perturbed bile salt homeostasis but no impairment in bile secretion.

Q9UT49	CID13_SCHPO	Poly(A) RNA polymerase cid13	12062100	Cid13 is a cytoplasmic poly(A) polymerase that regulates ribonucleotide reductase mRNA.

O43283	M3K13_HUMAN	Mitogen-activated protein kinase kinase kinase 13	12492477	Mixed lineage kinase LZK and antioxidant protein-1 activate NF-kappaB synergistically.

Q9Y468	LMBL1_HUMAN	Lethal(3)malignant brain tumor-like protein	10445843	A human homolog of Drosophila lethal(3)malignant brain tumor (l(3)mbt) protein associates with condensed mitotic chromosomes.

P19091	ANDR_MOUSE	Androgen receptor	15199138	Dyrk1A potentiates steroid hormone-induced transcription via the chromatin remodeling factor Arip4.

P78395	PRAME_HUMAN	Melanoma antigen preferentially expressed in tumors	16179254	The human tumor antigen PRAME is a dominant repressor of retinoic acid receptor signaling.

Q941Q3	C3H37_ARATH	Zinc finger CCCH domain-containing protein 37	12530963	Two RNA binding proteins, HEN4 and HUA1, act in the processing of AGAMOUS pre-mRNA in Arabidopsis thaliana.

Q09969	BNIP3_CAEEL	NIP3 homolog	9824163	Regulation of apoptosis by a Caenorhabditis elegans BNIP3 homolog.

A5D8Q0	XIAP_XENLA	Baculoviral IAP repeat-containing protein 4	15853809	Apoptosis-inhibiting activities of BIR family proteins in Xenopus egg extracts.

P41318	LST8_YEAST	Target of rapamycin complex subunit LST8	9409822	Control of amino acid permease sorting in the late secretory pathway of Saccharomyces cerevisiae by SEC13, LST4, LST7 and LST8.

Q86WV1	SKAP1_HUMAN	Src kinase-associated phosphoprotein 1	9195899	Molecular cloning of SKAP55, a novel protein that associates with p59fyn in human T-lymphocytes.

P53803	RPAB4_HUMAN	DNA-directed RNA polymerases I, II, and III subunit RPABC4	7651387	Four subunits that are shared by the three classes of RNA polymerase are functionally interchangeable between Homo sapiens and Saccharomyces cerevisiae.

O60271	JIP4_HUMAN	C-Jun-amino-terminal kinase-interacting protein 4	14743216	A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.

P38732	EFM1_YEAST	N-lysine methyltransferase EFM1	14562095	Global analysis of protein localization in budding yeast.

O60182	RFC1_SCHPO	Replication factor C subunit 1	16040599	Contrasting effects of Elg1-RFC and Ctf18-RFC inactivation in the absence of fully functional RFC in fission yeast.

Q9WTQ2	PODXL_RAT	Podocalyxin	11457882	Loss of glomerular foot processes is associated with uncoupling of podocalyxin from the actin cytoskeleton.

O95425	SVIL_HUMAN	Supervillin	12711699	Archvillin, a muscle-specific isoform of supervillin, is an early expressed component of the costameric membrane skeleton.

P57083	GD_HHV1P	Envelope glycoprotein D	11511370	Herpes simplex virus glycoprotein D bound to the human receptor HveA.

Q99314	SAS5_YEAST	Something about silencing protein 5	12626510	Sas4 and Sas5 are required for the histone acetyltransferase activity of Sas2 in the SAS complex.

P34711	UNC17_CAEEL	Vesicular acetylcholine transporter unc-17	8342028	The Caenorhabditis elegans unc-17 gene: a putative vesicular acetylcholine transporter.

O14593	RFXK_HUMAN	DNA-binding protein RFXANK	10072068	RFX-B is the gene responsible for the most common cause of the bare lymphocyte syndrome, an MHC class II immunodeficiency.

P96240	PHEA_MYCTU	Prephenate dehydratase	15753077	pheA (Rv3838c) of Mycobacterium tuberculosis encodes an allosterically regulated monofunctional prephenate dehydratase that requires both catalytic and regulatory domains for optimum activity.

P36060	MCR1_YEAST	NADH-cytochrome b5 reductase 2	8001120	Incomplete arrest in the outer membrane sorts NADH-cytochrome b5 reductase to two different submitochondrial compartments.

Q23120	RSP2_CAEEL	Probable splicing factor, arginine/serine-rich 2	10747030	Functional characterization of SR and SR-related genes in Caenorhabditis elegans.

Q03792	RIM13_YEAST	Calpain-like protease 1	11283351	A comprehensive two-hybrid analysis to explore the yeast protein interactome.

Q6DYE4	Y1609_ARATH	Uncharacterized protein At1g26090, chloroplastic	16461379	Protein profiling of plastoglobules in chloroplasts and chromoplasts. A surprising site for differential accumulation of metabolic enzymes.

Q9UT61	MAN1_SCHPO	Alpha-mannosidase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P53177	TYW3_YEAST	tRNA wybutosine-synthesizing protein 3	16642040	Biosynthesis of wybutosine, a hyper-modified nucleoside in eukaryotic phenylalanine tRNA.

Q7Z4T9	AAT1_HUMAN	AMY-1-associating protein expressed in testis 1	12223483	AAT-1, a novel testis-specific AMY-1-binding protein, forms a quaternary complex between AMY-1, A-kinase anchor protein 84 and a regulatory subunit of cAMP-dependent protein kinase and is phosphorylated by its kinase.

P30561	AHR_MOUSE	Aryl hydrocarbon receptor	1314586	cDNA cloning and structure of mouse putative Ah receptor.

Q4WG11	XYNA_ASPFU	Endo-1,4-beta-xylanase xynf11a	19577187	Cloning and expression of GH11 xylanase gene from Aspergillus fumigatus MKU1 in Pichia pastoris.

P38274	HSL7_YEAST	Protein arginine N-methyltransferase HSL7	10490630	The morphogenesis checkpoint in Saccharomyces cerevisiae: cell cycle control of Swe1p degradation by Hsl1p and Hsl7p.

Q9ZSY8	IAA27_ARATH	Auxin-responsive protein IAA27	12036262	Genetics of Aux/IAA and ARF action in plant growth and development.

P70196	TRAF6_MOUSE	TNF receptor-associated factor 6	14499111	TRAF6 is a critical factor for dendritic cell maturation and development.

O76013	KRT36_HUMAN	Keratin, type I cuticular Ha6	9756910	Characterization of a 190-kilobase pair domain of human type I hair keratin genes.

P36018	YPT52_YEAST	GTP-binding protein YPT52	11785952	Saccharomyces cerevisiae Pra1p/Yip3p interacts with Yip1p and Rab proteins.

P32558	SPT16_YEAST	FACT complex subunit SPT16	9199353	The Saccharomyces cerevisiae DNA polymerase alpha catalytic subunit interacts with Cdc68/Spt16 and with Pob3, a protein similar to an HMG1-like protein.

P87114	FFT1_SCHPO	Uncharacterized ATP-dependent helicase fft1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P51572	BAP31_HUMAN	B-cell receptor-associated protein 31	9334338	p28 Bap31, a Bcl-2/Bcl-XL- and procaspase-8-associated protein in the endoplasmic reticulum.

O60658	PDE8A_HUMAN	High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	9618252	Isolation and characterization of PDE8A, a novel human cAMP-specific phosphodiesterase.

Q9FM79	PME62_ARATH	Pectinesterase QRT1	16980565	Separation of Arabidopsis pollen tetrads is regulated by QUARTET1, a pectin methylesterase gene.

Q9UK39	NOCT_HUMAN	Nocturnin	10521507	Characterization of a mammalian gene related to the yeast CCR4 general transcription factor and revealed by transposon insertion.

Q9Z0S9	PRAF1_MOUSE	Prenylated Rab acceptor protein 1	11535589	Membrane topography and topogenesis of prenylated Rab acceptor (PRA1).

Q08188	TGM3_HUMAN	Protein-glutamine gamma-glutamyltransferase E	8099584	The deduced sequence of the novel protransglutaminase E (TGase3) of human and mouse.

O59751	KLP6_SCHPO	Kinesin-like protein 6	11967147	Two kinesin-like Kin I family proteins in fission yeast regulate the establishment of metaphase and the onset of anaphase A.

P32361	IRE1_YEAST	Serine/threonine-protein kinase/endoribonuclease IRE1	8663458	The unfolded protein response pathway in Saccharomyces cerevisiae. Oligomerization and trans-phosphorylation of Ire1p (Ern1p) are required for kinase activation.

Q07794	RT109_YEAST	Histone acetyltransferase RTT109	11779788	Multiple regulators of Ty1 transposition in Saccharomyces cerevisiae have conserved roles in genome maintenance.

P49333	ETR1_ARATH	Ethylene receptor 1	8211181	Arabidopsis ethylene-response gene ETR1: similarity of product to two-component regulators.

Q54HS9	AP1M_DICDI	AP-1 complex subunit mu	12802059	The AP-1 clathrin-adaptor is required for lysosomal enzymes sorting and biogenesis of the contractile vacuole complex in Dictyostelium cells.

Q62599	MTA1_RAT	Metastasis-associated protein MTA1	10393810	A novel zymogen granule protein (ZG29p) and the nuclear protein MTA1p are differentially expressed by alternative transcription initiation in pancreatic acinar cells of the rat.

Q9XIE2	AB36G_ARATH	ABC transporter G family member 36	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

O49686	PYR1_ARATH	Abscisic acid receptor PYR1	19407142	Abscisic acid inhibits type 2C protein phosphatases via the PYR/PYL family of START proteins.

Q06178	NMA1_YEAST	Nicotinamide-nucleotide adenylyltransferase 1	10428462	Identification and characterization of YLR328W, the Saccharomyces cerevisiae structural gene encoding NMN adenylyltransferase. Expression and characterization of the recombinant enzyme.

Q03790	NUP53_YEAST	Nucleoporin NUP53	9864357	Specific binding of the karyopherin Kap121p to a subunit of the nuclear pore complex containing Nup53p, Nup59p, and Nup170p.

Q9NPY3	C1QR1_HUMAN	Complement component C1q receptor	9047234	cDNA cloning and primary structure analysis of C1qR(P), the human C1q/MBL/SPA receptor that mediates enhanced phagocytosis in vitro.

P05496	AT5G1_HUMAN	ATP synthase lipid-binding protein, mitochondrial	8328972	Sequences of members of the human gene family for the c subunit of mitochondrial ATP synthase.

P50745	SH2B3_RAT	SH2B adapter protein 3	8524815	Cloning and characterization of Lnk, a signal transduction protein that links T-cell receptor activation signal to phospholipase C gamma 1, Grb2, and phosphatidylinositol 3-kinase.

O15075	DCLK1_HUMAN	Serine/threonine-protein kinase DCLK1	10051403	Genomic structure, chromosomal mapping, and expression pattern of human DCAMKL1 (KIAA0369), a homologue of DCX (XLIS).

P61296	HAND2_HUMAN	Heart- and neural crest derivatives-expressed protein 2	9878849	Molecular cloning of the human HAND2 gene.

Q9NRC6	SPTN5_HUMAN	Spectrin beta chain, brain 4	10764729	Identification and characterization of beta V spectrin, a mammalian ortholog of Drosophila beta H spectrin.

P37595	IAAA_ECOLI	Isoaspartyl peptidase	15265041	Expression, purification and catalytic activity of Lupinus luteus asparagine beta-amidohydrolase and its Escherichia coli homolog.

Q04636	POB3_YEAST	FACT complex subunit POB3	10924459	POB3 is required for both transcription and replication in the yeast Saccharomyces cerevisiae.

P85057	RN2SA_RANSV	Ranatuerin-2SEa	16386333	Histamine-releasing and antimicrobial peptides from the skin secretions of the dusky gopher frog, Rana sevosa.

O00303	EIF3F_HUMAN	Eukaryotic translation initiation factor 3 subunit F	17322308	Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry.

Q8LDI5	CXXS1_ARATH	Thioredoxin-like protein CXXS1	18384502	AtCXXS: atypical members of the Arabidopsis thaliana thioredoxin h family with a remarkably high disulfide isomerase activity.

Q9Y337	KLK5_HUMAN	Kallikrein-5	19194479	SPINK9: a selective, skin-specific Kazal-type serine protease inhibitor.

O95405	ZFYV9_HUMAN	Zinc finger FYVE domain-containing protein 9	12154125	Smad3 allostery links TGF-beta receptor kinase activation to transcriptional control.

Q9UT06	YLWB_SCHPO	Uncharacterized GTP-binding protein P8A3.11c, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O35987	NSF1C_RAT	NSFL1 cofactor p47	9214505	p47 is a cofactor for p97-mediated membrane fusion.

P01818	HV205_HUMAN	Ig heavy chain V-II region HE	5264153	Subgroups of amino acid sequences in the variable regions of immunoglobulin heavy chains.

P27933	AMY3D_ORYSJ	Alpha-amylase isozyme 3D	2370848	The alpha-amylase genes in Oryza sativa: characterization of cDNA clones and mRNA expression during seed germination.

Q6BCY4	NB5R2_HUMAN	NADH-cytochrome b5 reductase 2	10611283	Identification of a cytochrome b-type NAD(P)H oxidoreductase ubiquitously expressed in human cells.

Q16206	ENOX2_HUMAN	Ecto-NOX disulfide-thiol exchanger 2	11488599	Surface NADH oxidase of HeLa cells lacks intrinsic membrane binding motifs.

P47176	BCA2_YEAST	Branched-chain-amino-acid aminotransferase, cytosolic	8702755	Two yeast homologs of ECA39, a target for c-Myc regulation, code for cytosolic and mitochondrial branched-chain amino acid aminotransferases.

Q9NSB4	KRT82_HUMAN	Keratin, type II cuticular Hb2	10692104	Characterization of a 300 kbp region of human DNA containing the type II hair keratin.

Q2TXS4	PELD_ASPOR	Pectin lyase 2	16233008	A second pectin lyase gene (pel2) from Aspergillus oryzae KBN616: its sequence analysis and overexpression, and characterization of the gene products.

O14470	SSR2_SCHPO	SWI/SNF and RSC complexes subunit ssr2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q91620	NOD2A_XENLA	Nodal homolog 2-A	8582278	Nodal-related signals induce axial mesoderm and dorsalize mesoderm during gastrulation.

P48240	MTR3_YEAST	Exosome complex component MTR3	8534909	Mutations in nucleolar proteins lead to nucleolar accumulation of polyA+ RNA in Saccharomyces cerevisiae.

Q15029	U5S1_HUMAN	116 kDa U5 small nuclear ribonucleoprotein component	9233818	An evolutionarily conserved U5 snRNP-specific protein is a GTP- binding factor closely related to the ribosomal translocase EF-2.

Q96FX7	TRM61_HUMAN	tRNA (adenine-N(1)-)-methyltransferase catalytic subunit TRMT61A	16043508	The bipartite structure of the tRNA m1A58 methyltransferase from S. cerevisiae is conserved in humans.

Q9P6L9	YKQ7_SCHPO	Uncharacterized protein C688.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P22626	ROA2_HUMAN	Heterogeneous nuclear ribonucleoproteins A2/B1	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

P29674	LHX1_XENLA	LIM/homeobox protein Lhx1	10913356	RNA interference for the organizer-specific gene Xlim-1 in Xenopus embryos.

P61213	ARL4A_MOUSE	ADP-ribosylation factor-like protein 4A	9761722	The mouse ADP-ribosylation factor-like 4 gene: two separate promoters direct specific transcription in tissues and testicular germ cell.

P43609	RSC8_YEAST	Chromatin structure-remodeling complex protein RSC8	12684875	Dissecting the pet18 mutation in Saccharomyces cerevisiae: HTL1 encodes a 7-kDa polypeptide that interacts with components of the RSC complex.

Q19127	NPC1_CAEEL	Niemann-Pick C1 protein homolog 1	10801441	A model for Niemann-Pick type C disease in the nematode Caenorhabditis elegans.

Q9P6M7	MUG99_SCHPO	Meiotically up-regulated gene 99 protein, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12375	ORT1_YEAST	Mitochondrial ornithine carrier protein	8798783	The ARG11 gene of Saccharomyces cerevisiae encodes a mitochondrial integral membrane protein required for arginine biosynthesis.

O00213	APBB1_HUMAN	Amyloid beta A4 precursor protein-binding family B member 1	8894693	cDNA cloning and chromosome mapping of the human Fe65 gene: interaction of the conserved cytoplasmic domains of the human beta- amyloid precursor protein and its homologues with the mouse Fe65 protein.

Q9PUK8	FZD7A_XENLA	Frizzled-7-A	10727861	Xenopus frizzled 7 can act in canonical and non-canonical Wnt signaling pathways: implications on early patterning and morphogenesis.

O57311	ZIC3_XENLA	Zinc finger protein ZIC 3	11044394	Zic3 is involved in the left-right specification of the Xenopus embryo.

Q02388	CO7A1_HUMAN	Collagen alpha-1(VII) chain	9375848	Molecular basis of dystrophic epidermolysis bullosa: mutations in the type VII collagen gene (COL7A1).

O60174	SFC6_SCHPO	Transcription factor tau subunit sfc6	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q6U7H8	PI5L1_MOUSE	Phosphatidylinositol-4-phosphate 5-kinase-like protein 1	14701839	Identification and characterization of a phosphoinositide phosphate kinase homolog.

Q03824	INP2_YEAST	Inheritance of peroxisomes protein 2	16678774	The peroxisomal membrane protein Inp2p is the peroxisome-specific receptor for the myosin V motor Myo2p of Saccharomyces cerevisiae.

Q12405	LPX1_YEAST	Peroxisomal membrane protein LPX1	18199283	Lpx1p is a peroxisomal lipase required for normal peroxisome morphology.

O75116	ROCK2_HUMAN	Rho-associated protein kinase 2	9933571	Localization of the gene coding for ROCK II/Rho kinase on human chromosome 2p24.

Q95RJ9	EBI_DROME	F-box-like/WD repeat-containing protein ebi	11032805	A role for Ebi in neuronal cell cycle control.

O95631	NET1_HUMAN	Netrin-1	19196994	DSCAM functions as a netrin receptor in commissural axon pathfinding.

Q8N5Z0	AADAT_HUMAN	Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial	18620547	Substrate specificity and structure of human aminoadipate aminotransferase/kynurenine aminotransferase II.

Q04836	ROC3_ARATH	31 kDa ribonucleoprotein, chloroplastic	7894017	Three types of nuclear genes encoding chloroplast RNA-binding proteins (cp29, cp31 and cp33) are present in Arabidopsis thaliana: presence of cp31 in chloroplasts and its homologue in nuclei/cytoplasms.

Q7Z460	CLAP1_HUMAN	CLIP-associating protein 1	11290329	Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts.

P55884	EIF3B_HUMAN	Eukaryotic translation initiation factor 3 subunit B	11169732	Molecular interaction between human tumor marker protein p150, the largest subunit of eIF3, and intermediate filament protein K7.

Q09884	DCR1_SCHPO	Protein Dicer	14699070	ago1 and dcr1, two core components of the RNA interference pathway, functionally diverge from rdp1 in regulating cell cycle events in Schizosaccharomyces pombe.

Q8LMR2	DCL1_ORYSJ	Endoribonuclease Dicer homolog 1	16126864	Loss of function of OsDCL1 affects microRNA accumulation and causes developmental defects in rice.

O70362	PHLD_MOUSE	Phosphatidylinositol-glycan-specific phospholipase D	9716655	Mouse glycosylphosphatidylinositol-specific phospholipase D (Gpld1) characterization.

Q92667	AKAP1_HUMAN	A-kinase anchor protein 1, mitochondrial	8769136	Molecular characterization of AKAP149, a novel A kinase anchor protein with a KH domain.

P87241	RIB2_SCHPO	Diaminohydroxyphosphoribosylamino-pyrimidine deaminase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O88496	VKGC_RAT	Vitamin K-dependent gamma-carboxylase	9743593	Cloning of rat vitamin K-dependent gamma-glutamyl carboxylase and developmentally regulated gene expression in post-implantation embryos.

Q03405	UPAR_HUMAN	Urokinase plasminogen activator surface receptor	18718938	Epileptic and developmental disorders of the speech cortex: ligand/receptor interaction of wild-type and mutant SRPX2 with the plasminogen activator receptor uPAR.

Q55DR6	FCSA_DICDI	Fatty acyl-CoA synthetase A	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q8L7B5	CH60B_ARATH	Chaperonin CPN60-like 1, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P19524	MYO2_YEAST	Myosin-2	15201867	Mmr1p is a mitochondrial factor for Myo2p-dependent inheritance of mitochondria in the budding yeast.

Q64612	PTPRV_RAT	Receptor-type tyrosine-protein phosphatase V	7527035	Identification of a hormonally regulated protein tyrosine phosphatase associated with bone and testicular differentiation.

Q9NPG4	PCD12_HUMAN	Protocadherin-12	10716726	Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.

Q60631	GRB2_MOUSE	Growth factor receptor-bound protein 2	19597497	Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection.

Q6P4R8	NFRKB_HUMAN	Nuclear factor related to kappa-B-binding protein	18922472	Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex.

P58499	FAM3B_HUMAN	Protein FAM3B	12160727	Cloning, expression, and initial characterization of a novel cytokine-like gene family.

P49446	PTPRE_MOUSE	Receptor-type tyrosine-protein phosphatase epsilon	12861030	Dimerization in vivo and inhibition of the nonreceptor form of protein tyrosine phosphatase epsilon.

Q16352	AINX_HUMAN	Alpha-internexin	7769995	Cloning and developmental expression of human 66 kd neurofilament protein.

Q39112	GAOX3_ARATH	Gibberellin 20 oxidase 3	7630935	Isolation and expression of three gibberellin 20-oxidase cDNA clones from Arabidopsis.

P36010	NDK_YEAST	Nucleoside diphosphate kinase	1659321	Saccharomyces cerevisiae nucleoside-diphosphate kinase: purification, characterization, and substrate specificity.

P64530	RCNR_ECOLI	Transcriptional repressor rcnR	17120142	The RcnRA (YohLM) system of Escherichia coli: a connection between nickel, cobalt and iron homeostasis.

P84276	PA1C_RANPA	Palustrin-1c	11087945	Multiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris.

P23803	ODD_DROME	Protein odd-skipped	7750646	Establishing parasegments in Drosophila embryos: roles of the odd- skipped and naked genes.

Q7YSW8	PP2BA_DICDI	Calcineurin subunit A	9765812	Overexpression, purification and characterization of Dictyostelium calcineurin A.

Q05123	ARP9_YEAST	Actin-like protein ARP9	16204215	The RSC chromatin remodeling complex bears an essential fungal- specific protein module with broad functional roles.

Q08970	MMT2_YEAST	Mitochondrial metal transporter 2	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q8IVS2	FABD_HUMAN	Malonyl-CoA-acyl carrier protein transacylase, mitochondrial	12882974	Cloning, expression, characterization, and interaction of two components of a human mitochondrial fatty acid synthase. Malonyltransferase and acyl carrier protein.

Q8K4G1	LTBP4_MOUSE	Latent-transforming growth factor beta-binding protein 4	12208849	Disruption of the gene encoding the latent transforming growth factor-beta binding protein 4 (LTBP-4) causes abnormal lung development, cardiomyopathy, and colorectal cancer.

P25038	IF2M_YEAST	Translation initiation factor IF-2, mitochondrial	1935960	Mitochondrial translational-initiation and elongation factors in Saccharomyces cerevisiae.

Q12050	ELG1_YEAST	Telomere length regulation protein ELG1	13678589	Elg1 forms an alternative PCNA-interacting RFC complex required to maintain genome stability.

Q8CG85	MAMC2_MOUSE	MAM domain-containing protein 2	18757743	Transcriptome-based systematic identification of extracellular matrix proteins.

Q8R500	MFN2_RAT	Mitofusin-2	14561718	Two mitofusin proteins, mammalian homologues of FZO, with distinct functions are both required for mitochondrial fusion.

Q9FT72	RQL3_ARATH	ATP-dependent DNA helicase Q-like 3	19755539	Biochemical characterization of AtRECQ3 reveals significant differences relative to other RecQ helicases.

P38911	FKBP3_YEAST	FK506-binding nuclear protein	7525596	A novel FK506- and rapamycin-binding protein (FPR3 gene product) in the yeast Saccharomyces cerevisiae is a proline rotamase localized to the nucleolus.

P02747	C1QC_HUMAN	Complement C1q subcomponent subunit C	9777412	Molecular basis of hereditary C1q deficiency.

O64883	BGL26_ARATH	Beta-glucosidase 26, peroxisomal	16293760	Pre- and postinvasion defenses both contribute to nonhost resistance in Arabidopsis.

P0A7T3	RS16_ECOLI	30S ribosomal protein S16	8730873	The Escherichia coli ribosomal protein S16 is an endonuclease.

P09624	DLDH_YEAST	Dihydrolipoyl dehydrogenase, mitochondrial	7498764	Genetics of the synthesis of serine from glycine and the utilization of glycine as sole nitrogen source by Saccharomyces cerevisiae.

P12107	COBA1_HUMAN	Collagen alpha-1(XI) chain	8872475	A family with Stickler syndrome type 2 has a mutation in the COL11A1 gene resulting in the substitution of glycine 97 by valine in alpha- 1(XI) collagen.

Q08211	DHX9_HUMAN	ATP-dependent RNA helicase A	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

P13130	SS100_YEAST	Sporulation-specific wall maturation protein	3280971	The SPS100 gene of Saccharomyces cerevisiae is activated late in the sporulation process and contributes to spore wall maturation.

Q96I24	FUBP3_HUMAN	Far upstream element-binding protein 3	8940189	The far upstream element-binding proteins comprise an ancient family of single-strand DNA-binding transactivators.

Q9Y117	GALT3_DROME	Polypeptide N-acetylgalactosaminyltransferase 3	12829714	Functional characterization and expression analysis of members of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family from Drosophila melanogaster.

Q8IRC7	AWH_DROME	LIM/homeobox protein Awh	9331336	Arrowhead encodes a LIM homeodomain protein that distinguishes subsets of Drosophila imaginal cells.

Q16557	PSG3_HUMAN	Pregnancy-specific beta-1-glycoprotein 3	2341148	Structure, evolution and chromosomal localization of the human pregnancy-specific beta 1 glycoprotein gene family.

P0A6P9	ENO_ECOLI	Enolase	16516921	Recognition of enolase in the Escherichia coli RNA degradosome.

Q12209	FRE8_YEAST	Probable ferric reductase transmembrane component 8	14534306	Exploratory and confirmatory gene expression profiling of mac1Delta.

P48758	CBR1_MOUSE	Carbonyl reductase [NADPH] 1	8661038	Cloning a cDNA for carbonyl reductase (Cbr) from mouse cerebellum: murine genes that express cbr map to chromosomes 16 and 11.

P11509	CP2A6_HUMAN	Cytochrome P450 2A6	16086027	Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen.

Q60614	AA2BR_MOUSE	Adenosine receptor A2b	8157966	Cloning of two adenosine receptor subtypes from mouse bone marrow- derived mast cells.

O13702	GLD1_SCHPO	Glycerol dehydrogenase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9V5M6	LOLA5_DROME	Longitudinals lacking protein, isoforms J/P/Q/S/Z	12538650	A developmentally regulated splice variant from the complex lola locus encoding multiple different zinc finger domain proteins interacts with the chromosomal kinase JIL-1.

Q42993	CHI1_ORYSJ	Chitinase 1	8605293	Regulation, expression and function of a new basic chitinase gene in rice (Oryza sativa L.).

Q92608	DOCK2_HUMAN	Dedicator of cytokinesis protein 2	10559471	Non-adherent cell-specific expression of DOCK2, a member of the human CDM-family proteins.

P25359	RRP43_YEAST	Exosome complex component RRP43	9390555	The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases.

P18414	ERD2_YEAST	ER lumen protein retaining receptor	2194670	ERD2, a yeast gene required for the receptor-mediated retrieval of luminal ER proteins from the secretory pathway.

P25846	MSH1_YEAST	DNA mismatch repair protein MSH1, mitochondrial	1334021	Characterization of insertion mutations in the Saccharomyces cerevisiae MSH1 and MSH2 genes: evidence for separate mitochondrial and nuclear functions.

P42261	GRIA1_HUMAN	Glutamate receptor 1	1311100	Molecular cloning, chromosomal mapping, and functional expression of human brain glutamate receptors.

Q9EQC5	NTKL_MOUSE	N-terminal kinase-like protein	18556652	Scyl1, mutated in a recessive form of spinocerebellar neurodegeneration, regulates COPI-mediated retrograde traffic.

Q9FN69	GL3_ARATH	Transcription factor GLABRA 3	11063707	GL3 encodes a bHLH protein that regulates trichome development in arabidopsis through interaction with GL1 and TTG1.

P60214	SC49B_TITCA	Toxin Tc49b	15025998	Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

P40367	GPI7_YEAST	GPI ethanolamine phosphate transferase 2	10329735	Deletion of GPI7, a yeast gene required for addition of a side chain to the glycosylphosphatidylinositol (GPI) core structure, affects GPI protein transport, remodeling, and cell wall integrity.

Q9Z2R9	E2AK1_MOUSE	Eukaryotic translation initiation factor 2-alpha kinase 1	11560503	Multiple autophosphorylation is essential for the formation of the active and stable homodimer of heme-regulated eIF2alpha kinase.

Q9S841	PSBO2_ARATH	Oxygen-evolving enhancer protein 1-2, chloroplastic	11826309	Central functions of the lumenal and peripheral thylakoid proteome of Arabidopsis determined by experimentation and genome-wide prediction.

Q12096	GNT1_YEAST	Glucose N-acetyltransferase 1	12651885	An N-acetylglucosaminyltransferase of the Golgi apparatus of the yeast Saccharomyces cerevisiae that can modify N-linked glycans.

P76141	LSRR_ECOLI	Transcriptional regulator lsrR	15743955	Cyclic AMP (cAMP) and cAMP receptor protein influence both synthesis and uptake of extracellular autoinducer 2 in Escherichia coli.

Q8VWF8	RPOT2_NICSY	DNA-directed RNA polymerase 2, chloroplastic/mitochondrial	11741306	Dual targeting of phage-type RNA polymerase to both mitochondria and plastids is due to alternative translation initiation in single transcripts.

Q9FNX8	LOX4_ARATH	Lipoxygenase 4, chloroplastic	19054359	Nitric oxide modulates ozone-induced cell death, hormone biosynthesis and gene expression in Arabidopsis thaliana.

Q9P7N0	MUG11_SCHPO	Meiotically up-regulated gene 11 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q00472	PNPP_SCHPO	4-nitrophenylphosphatase	1645660	Characterisation of the specific p-nitrophenylphosphatase gene and protein of Schizosaccharomyces pombe.

P36159	RNZ_YEAST	Ribonuclease Z	12711671	A candidate prostate cancer susceptibility gene encodes tRNA 3' processing endoribonuclease.

P33240	CSTF2_HUMAN	Cleavage stimulation factor subunit 2	11389848	Evolutionarily conserved interaction between CstF-64 and PC4 links transcription, polyadenylation, and termination.

Q23917	PDE2_DICDI	3',5'-cyclic-nucleotide phosphodiesterase regA	10974109	Molecular basis for resistance to the anticancer drug cisplatin in Dictyostelium.

P52061	RDGB_ECOLI	Nucleoside-triphosphatase rdgB	12297000	Identification of the dITP- and XTP-hydrolyzing protein from Escherichia coli.

Q9H8S9	MOL1B_HUMAN	Mps one binder kinase activator-like 1B	15197186	Mechanism of activation of NDR (nuclear Dbf2-related) protein kinase by the hMOB1 protein.

O60934	NBN_HUMAN	Nibrin	10888888	Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres.

P38167	ECM21_YEAST	Protein ECM21	9335584	Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae.

Q91ZS3	CAB45_RAT	45 kDa calcium-binding protein	17442889	A cytosolic splice variant of Cab45 interacts with Munc18b and impacts on amylase secretion by pancreatic acini.

Q9NZT2	OGFR_HUMAN	Opioid growth factor receptor	10677613	Cloning, sequencing, chromosomal location, and function of cDNAs encoding an opioid growth factor receptor (OGFr) in humans.

O75907	DGAT1_HUMAN	Diacylglycerol O-acyltransferase 1	9756920	Characterization of two human genes encoding acyl coenzyme A:cholesterol acyltransferase-related enzymes.

Q6MG49	BAT3_RAT	Large proline-rich protein BAT3	10390159	Cloning and characterization of rat BAT3 cDNA.

Q04511	UFO1_YEAST	Ubiquitin ligase complex F-box protein UFO1	10963670	Functions of the DNA damage response pathway target Ho endonuclease of yeast for degradation via the ubiquitin-26S proteasome system.

Q9QUK6	TLR4_MOUSE	Toll-like receptor 4	17803912	Crystal structure of the TLR4-MD-2 complex with bound endotoxin antagonist Eritoran.

P31645	SC6A4_HUMAN	Sodium-dependent serotonin transporter	16870614	Subcellular redistribution of the serotonin transporter by secretory carrier membrane protein 2.

Q8GSQ1	C85A1_ORYSJ	Cytochrome P450 85A1	12445121	Loss-of-function of a rice brassinosteroid biosynthetic enzyme, C-6 oxidase, prevents the organized arrangement and polar elongation of cells in the leaves and stem.

Q8BG39	SV2B_MOUSE	Synaptic vesicle glycoprotein 2B	12687700	Differential distribution and developmental expression of synaptic vesicle protein 2 isoforms in the mouse retina.

O22781	SUVH2_ARATH	Histone-lysine N-methyltransferase, H3 lysine-9, H3 lysine-27, H4 lysine-20 and cytosine specific SUVH2	15775980	Pivotal role of AtSUVH2 in heterochromatic histone methylation and gene silencing in Arabidopsis.

O13864	IMB1_SCHPO	Importin subunit beta-1	15116432	Identification of genes encoding putative nucleoporins and transport factors in the fission yeast Schizosaccharomyces pombe: a deletion analysis.

Q9NRA1	PDGFC_HUMAN	Platelet-derived growth factor C	10806482	PDGF-C is a new protease-activated ligand for the PDGF alpha- receptor.

P30153	2AAA_HUMAN	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform	9989501	The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs.

Q12476	AIR2_YEAST	Protein AIR2	15935758	RNA degradation by the exosome is promoted by a nuclear polyadenylation complex.

O23512	PPD_ARATH	Probable pheophorbidase	18467465	Inactive methyl indole-3-acetic acid ester can be hydrolyzed and activated by several esterases belonging to the AtMES esterase family of Arabidopsis.

Q9NRI5	DISC1_HUMAN	Disrupted in schizophrenia 1 protein	12812986	DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation.

Q9C035	TRIM5_HUMAN	Tripartite motif-containing protein 5	11331580	The tripartite motif family identifies cell compartments.

O76054	S14L2_HUMAN	SEC14-like protein 2	10829015	A novel human tocopherol-associated protein: cloning, in vitro expression, and characterization.

Q01881	RA05_ORYSJ	Seed allergenic protein RA5	7669811	Classification of rice allergenic protein cDNAs belonging to the alpha-amylase/trypsin inhibitor gene family.

Q9STK6	WNK3_ARATH	Probable serine/threonine-protein kinase WNK3	12506983	Compilation and characterization of a novel WNK family of protein kinases in Arabiodpsis thaliana with reference to circadian rhythms.

O15061	SYNEM_HUMAN	Synemin	11353857	Desmuslin, an intermediate filament protein that interacts with alpha-dystrobrevin and desmin.

Q6GNW0	LRRF2_XENLA	Leucine-rich repeat flightless-interacting protein 2	15677333	Identification of the Wnt signaling activator leucine-rich repeat in Flightless interaction protein 2 by a genome-wide functional analysis.

Q9NZQ7	PD1L1_HUMAN	Programmed cell death 1 ligand 1	10581077	B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion.

Q96276	MYB23_ARATH	Transcription factor MYB23	15728674	Functional diversification of MYB23 and GL1 genes in trichome morphogenesis and initiation.

P23586	STP1_ARATH	Sugar transport protein 1	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

Q06551	ERFB_YEAST	Palmitoyltransferase ERF2	12193598	Identification of a Ras palmitoyltransferase in Saccharomyces cerevisiae.

Q9C026	TRIM9_HUMAN	E3 ubiquitin-protein ligase TRIM9	20085810	TRIM9, a novel brain-specific E3 ubiquitin ligase, is repressed in the brain of Parkinson's disease and dementia with Lewy bodies.

Q08202	OPI10_YEAST	Protein OPI10	14562095	Global analysis of protein localization in budding yeast.

O94656	YGF5_SCHPO	Meiotic chromosome segregation protein C405.05	16169489	Novel genes required for meiotic chromosome segregation are identified by a high-throughput knockout screen in fission yeast.

P83284	IBB1_AMBAC	Bowman-birk type proteinase inhibitor	8895102	Sequence of a new Bowman-Birk inhibitor from Torresea acreana seeds and comparison with Torresea cearensis trypsin inhibitor (TcTI2).

O88513	GEMI_MOUSE	Geminin	12192004	Mouse geminin inhibits not only Cdt1-MCM6 interactions but also a novel intrinsic Cdt1 DNA binding activity.

Q0QF01	DHSA_PIG	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	17480203	Preliminary molecular characterization and crystallization of mitochondrial respiratory complex II from porcine heart.

Q8BQB4	FJX1_MOUSE	Four-jointed box protein 1	16145673	Fjx1: a notch-inducible secreted ligand with specific binding sites in developing mouse embryos and adult brain.

P55018	S12A3_RAT	Solute carrier family 12 member 3	8021284	Molecular cloning, primary structure, and characterization of two members of the mammalian electroneutral sodium-(potassium)-chloride cotransporter family expressed in kidney.

P42575	CASP2_HUMAN	Caspase-2	11156409	Identification of a caspase-2 isoform that behaves as an endogenous inhibitor of the caspase cascade.

O60258	FGF17_HUMAN	Fibroblast growth factor 17	12975309	The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

P46891	COF_ECOLI	HMP-PP phosphatase	15292217	A genetic screen for the identification of thiamin metabolic genes.

O22446	HDA19_ARATH	Histone deacetylase 19	16429262	AtSAP18, an orthologue of human SAP18, is involved in the regulation of salt stress and mediates transcriptional repression in Arabidopsis.

Q8BH64	EHD2_MOUSE	EH domain-containing protein 2	14676205	EHD2 and the novel EH domain binding protein EHBP1 couple endocytosis to the actin cytoskeleton.

O75908	SOAT2_HUMAN	Sterol O-acyltransferase 2	11401500	Organization of human ACAT-2 gene and its cell-type-specific promoter activity.

P54968	ILR1_ARATH	IAA-amino acid hydrolase ILR1	11923288	Characterization of a family of IAA-amino acid conjugate hydrolases from Arabidopsis.

P28908	TNR8_HUMAN	Tumor necrosis factor receptor superfamily member 8	1310894	Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin's disease.

Q9UPT9	UBP22_HUMAN	Ubiquitin carboxyl-terminal hydrolase 22	18206972	A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing.

Q9Y7P6	MUG72_SCHPO	Meiotically up-regulated gene 72 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O74798	ALY2_SCHPO	Putative arrestin-related trafficking adapter C2D10.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q00916	RU17_YEAST	U1 small nuclear ribonucleoprotein 70 kDa homolog	1387202	The yeast homolog of the U1 snRNP protein 70K is encoded by the SNP1 gene.

Q3T1J1	IF5A1_RAT	Eukaryotic translation initiation factor 5A-1	18606156	Insights on eukaryotic translation initiation factor 5A (eIF5A) in the brain and aging.

Q95VF0	PBP2_EPIPO	Pheromone-binding protein 2	12530222	Pheromone binding proteins of Epiphyas postvittana (Lepidoptera: Tortricidae) are encoded at a single locus.

Q9AYP9	LECC_PHYAM	Lectin-C	7670205	The complete amino acid sequence of lectin-C from the roots of pokeweed (Phytolacca americana).

P10733	SEVE_DICDI	Severin	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q9Z221	PMFBP_RAT	Polyamine-modulated factor 1-binding protein 1	11774381	Molecular cloning of Odf3 encoding a novel coiled-coil protein of sperm tail outer dense fibers.

Q8WTR7	ZN473_HUMAN	Zinc finger protein 473	16714279	Conserved zinc fingers mediate multiple functions of ZFP100, a U7snRNP associated protein.

Q9GNK5	PGPLC_DROME	Peptidoglycan-recognition protein LC	12777387	Functional diversity of the Drosophila PGRP-LC gene cluster in the response to lipopolysaccharide and peptidoglycan.

Q9ET20	SCAM4_RAT	Secretory carrier-associated membrane protein 4	11295240	Expression of the SCAMP-4 gene, a new member of the secretory carrier membrane protein family, is repressed by progesterone in brain regions associated with female sexual behavior.

Q8MXY0	AMT3_DICDI	Ammonium transporter 3	14686953	Temporal and spatial expression of ammonium transporter genes during growth and development of Dictyostelium discoideum.

O54960	CAPON_RAT	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein	9459447	CAPON: a protein associated with neuronal nitric oxide synthase that regulates its interactions with PSD95.

Q9VJ79	PDE11_DROME	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11	15673286	Cyclic nucleotide phosphodiesterases in Drosophila melanogaster.

Q769K2	NAPEP_RAT	N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D	14634025	Molecular characterization of a phospholipase D generating anandamide and its congeners.

P63312	TYB10_RAT	Thymosin beta-10	1744129	Cloning and characterization of a testis-specific thymosin beta 10 cDNA. Expression in post-meiotic male germ cells.

P24348	LET23_CAEEL	Receptor tyrosine-protein kinase let-23	10359617	Basolateral localization of the Caenorhabditis elegans epidermal growth factor receptor in epithelial cells by the PDZ protein lin- 10.

Q8K1M8	FAM5B_RAT	Protein FAM5B	15193423	Identification and characterization of novel developmentally regulated neural-specific proteins, BRINP family.

O60516	4EBP3_HUMAN	Eukaryotic translation initiation factor 4E-binding protein 3	9593750	4E-BP3, a new member of the eukaryotic initiation factor 4E-binding protein family.

O13587	YP096_YEAST	Uncharacterized protein YPR096C	16702403	Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes.

P24612	MEC4_CAEEL	Degenerin mec-4	12478294	The mechanosensory protein MEC-6 is a subunit of the C. elegans touch-cell degenerin channel.

Q9SPL2	CIP8_ARATH	E3 ubiquitin-protein ligase CIP8	12028569	Biochemical evidence for ubiquitin ligase activity of the Arabidopsis COP1 interacting protein 8 (CIP8).

Q9USZ0	YNA2_SCHPO	Uncharacterized WD repeat-containing protein C1306.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P15919	RAG1_MOUSE	V(D)J recombination-activating protein 1	1547488	RAG-1-deficient mice have no mature B and T lymphocytes.

P35180	TOM20_YEAST	Mitochondrial import receptor subunit TOM20	9774667	Preprotein translocase of the outer mitochondrial membrane: molecular dissection and assembly of the general import pore complex.

Q3HS82	AMTN_RAT	Amelotin	16787391	Cloning of rat amelotin and localization of the protein to the basal lamina of maturation stage ameloblasts and junctional epithelium.

Q9QZ81	AGO2_RAT	Protein argonaute-2	10512872	GERp95, a membrane-associated protein that belongs to a family of proteins involved in stem cell differentiation.

Q18801	GMD1_CAEEL	GDP-mannose 4,6 dehydratase 1	16650000	Reconstitution in vitro of the GDP-fucose biosynthetic pathways of Caenorhabditis elegans and Drosophila melanogaster.

P39706	SWD1_YEAST	COMPASS component SWD1	11805083	COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression.

Q9UJY4	GGA2_HUMAN	ADP-ribosylation factor-binding protein GGA2	12505986	Divalent interaction of the GGAs with the Rabaptin-5-Rabex-5 complex.

O13854	ADG2_SCHPO	Serine/threonine-rich protein adg2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P70429	EVL_MOUSE	Ena/VASP-like protein	10993894	The orthologous human and murine semaphorin 6A-1 proteins (SEMA6A- 1/Sema6A-1) bind to the enabled/vasodilator-stimulated phosphoprotein- like protein (EVL) via a novel carboxyl-terminal zyxin-like domain.

Q9S851	NAC31_ARATH	Protein CUP-SHAPED COTYLEDON 3	12837947	The CUP-SHAPED COTYLEDON3 gene is required for boundary and shoot meristem formation in Arabidopsis.

Q9DBU5	RNF6_MOUSE	E3 ubiquitin-protein ligase RNF6	16204183	The ubiquitin ligase Rnf6 regulates local LIM kinase 1 levels in axonal growth cones.

Q86IA3	PDI1_DICDI	Protein disulfide-isomerase 1	9428745	Dictyostelium discoideum protein disulfide isomerase, an endoplasmic reticulum resident enzyme lacking a KDEL-type retrieval signal.

Q9FUY2	LEUNG_ARATH	Transcriptional corepressor LEUNIG	11782418	SEUSS, a member of a novel family of plant regulatory proteins, represses floral homeotic gene expression with LEUNIG.

P25554	SGF29_YEAST	SAGA-associated factor 29	12052880	Proteomics of the eukaryotic transcription machinery: identification of proteins associated with components of yeast TFIID by multidimensional mass spectrometry.

Q9C037	TRIM4_HUMAN	Tripartite motif-containing protein 4	11331580	The tripartite motif family identifies cell compartments.

Q9Y651	SOX21_HUMAN	Transcription factor SOX-21	10441749	The isolation and high-resolution chromosomal mapping of human SOX14 and SOX21; two members of the SOX gene family related to SOX1, SOX2, and SOX3.

O75533	SF3B1_HUMAN	Splicing factor 3B subunit 1	9585501	Phosphorylation of spliceosomal protein SAP 155 coupled with splicing catalysis.

Q9NWB1	FOX1A_HUMAN	Fox-1 homolog A	10814712	A novel protein with RNA-binding motifs interacts with ataxin-2.

Q80Z19	MUC2_MOUSE	Mucin-2	19432394	Proteomic analyses of the two mucus layers of the colon barrier reveal that their main component, the Muc2 mucin, is strongly bound to the Fcgbp protein.

Q9YH71	VNT1B_XENLA	Homeobox protein vent1B	10330491	Transcriptional regulation of Xvent homeobox genes.

O74774	HBS1_SCHPO	Elongation factor 1 alpha-like protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O75925	PIAS1_HUMAN	E3 SUMO-protein ligase PIAS1	9724754	Inhibition of Stat1-mediated gene activation by PIAS1.

Q9WTJ5	RAMP1_MOUSE	Receptor activity-modifying protein 1	10854696	Mouse receptor-activity-modifying proteins 1, -2 and -3: amino acid sequence, expression and function.

Q01892	SPIB_HUMAN	Transcription factor Spi-B	8670269	An alternatively spliced isoform of the Spi-B transcription factor.

P21397	AOFA_HUMAN	Amine oxidase [flavin-containing] A	8211186	Abnormal behavior associated with a point mutation in the structural gene for monoamine oxidase A.

P21731	TA2R_HUMAN	Thromboxane A2 receptor	1825698	Cloning and expression of cDNA for a human thromboxane A2 receptor.

P61964	WDR5_HUMAN	WD repeat-containing protein 5	19556245	On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex.

P38169	KMO_YEAST	Kynurenine 3-monooxygenase	15806102	A genomic screen in yeast implicates kynurenine 3-monooxygenase as a therapeutic target for Huntington disease.

P14373	TRI27_HUMAN	Zinc finger protein RFP	3380101	Developmentally regulated expression of a human 'finger'-containing gene encoded by the 5' half of the ret transforming gene.

P23588	IF4B_HUMAN	Eukaryotic translation initiation factor 4B	2390971	Cloning and expression of eukaryotic initiation factor 4B cDNA: sequence determination identifies a common RNA recognition motif.

Q93YP0	UEV1A_ARATH	Ubiquitin-conjugating enzyme E2 variant 1A	18178771	Arabidopsis UEV1D promotes lysine-63-linked polyubiquitination and is involved in DNA damage response.

Q08465	YNG1_YEAST	Protein YNG1	17157260	Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs.

O35465	FKBP8_MOUSE	Peptidyl-prolyl cis-trans isomerase FKBP8	15105374	FKBP8 is a negative regulator of mouse sonic hedgehog signaling in neural tissues.

P46963	CTK3_YEAST	CTD kinase subunit gamma	15520468	CTD kinase I is involved in RNA polymerase I transcription.

Q62962	ACCN1_RAT	Amiloride-sensitive cation channel 1, neuronal	9368048	A modulatory subunit of acid sensing ion channels in brain and dorsal root ganglion cells.

Q99M87	DNJA3_MOUSE	DnaJ homolog subfamily A member 3, mitochondrial	11116152	A mouse homologue of the Drosophila tumor suppressor l(2)tid gene defines a novel Ras GTPase-activating protein (RasGAP)-binding protein.

Q56ZN6	AVP2_ARATH	Pyrophosphate-energized membrane proton pump 2	11163790	Novel type Arabidopsis thaliana H(+)-PPase is localized to the Golgi apparatus.

O14242	YELB_SCHPO	Putative pyridoxal kinase C6F6.11c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9CR14	FANCL_MOUSE	E3 ubiquitin-protein ligase FANCL	12417526	A novel gene, Pog, is necessary for primordial germ cell proliferation in the mouse and underlies the germ cell deficient mutation, gcd.

O95644	NFAC1_HUMAN	Nuclear factor of activated T-cells, cytoplasmic 1	9506523	Solution structure of the core NFATC1/DNA complex.

Q96EV8	DTBP1_HUMAN	Dysbindin	16980328	Dysbindin-1 is a synaptic and microtubular protein that binds brain snapin.

P53812	PIPNB_RAT	Phosphatidylinositol transfer protein beta isoform	7961615	Cloning of a cDNA encoding a second phosphatidylinositol transfer protein of rat brain by complementation of the yeast sec14 mutation.

O13862	RDP1_SCHPO	Transcriptional activator protein rdp1	11073995	Rdp1, a novel zinc finger protein, regulates the DNA damage response of rhp51(+) from Schizosaccharomyces pombe.

O35142	COPB2_RAT	Coatomer subunit beta'	18556652	Scyl1, mutated in a recessive form of spinocerebellar neurodegeneration, regulates COPI-mediated retrograde traffic.

Q24563	DOPR2_DROME	Dopamine receptor 2	8656286	Cloning and functional characterization of a novel dopamine receptor from Drosophila melanogaster.

Q96J02	ITCH_HUMAN	E3 ubiquitin-protein ligase Itchy homolog	19580544	Endogenous spartin (SPG20) is recruited to endosomes and lipid droplets and interacts with the ubiquitin E3 ligases AIP4 and AIP5.

Q1MTR8	SVP26_SCHPO	Protein svp26	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

Q8CGV2	TPH2_MOUSE	Tryptophan 5-hydroxylase 2	12511643	Synthesis of serotonin by a second tryptophan hydroxylase isoform.

Q13952	NFYC_HUMAN	Nuclear transcription factor Y subunit gamma	9332362	Isolation and sequence analysis of the cDNA encoding subunit C of human CCAAT-binding transcription factor.

Q5FYA8	ARSH_HUMAN	Arylsulfatase H	16174644	Sulfatases and sulfatase modifying factors: an exclusive and promiscuous relationship.

Q7T103	P5F11_XENLA	POU domain, class 5, transcription factor 1.1	18922797	Oct25 represses transcription of nodal/activin target genes by interaction with signal transducers during Xenopus gastrulation.

P53148	SP105_YEAST	Spindle pole body component SPC105	9585415	Analysis of the Saccharomyces spindle pole by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry.

Q06819	DIB1_YEAST	Spliceosomal protein DIB1	10449419	Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6.U5] tri-snRNP.

P36613	CGM2_SCHPO	Cyclin mcs2	8557036	Schizosaccharomyces pombe Mop1-Mcs2 is related to mammalian CAK.

P84308	MOSA_AZOVD	Molybdenum storage protein subunit alpha	15651045	A new type of metalloprotein: the Mo storage protein from Azotobacter vinelandii contains a polynuclear molybdenum-oxide cluster.

P49747	COMP_HUMAN	Cartilage oligomeric matrix protein	11084047	Mutations in cartilage oligomeric matrix protein causing pseudoachondroplasia and multiple epiphyseal dysplasia affect binding of calcium and collagen I, II, and IX.

Q9LXS1	MTPA2_ARATH	Metal tolerance protein A2	16709200	The Arabidopsis metal tolerance protein AtMTP3 maintains metal homeostasis by mediating Zn exclusion from the shoot under Fe deficiency and Zn oversupply.

P16232	DHI1_RAT	Corticosteroid 11-beta-dehydrogenase isozyme 1	2808402	Cloning and expression of rat cDNA encoding corticosteroid 11 beta- dehydrogenase.

P48444	COPD_HUMAN	Coatomer subunit delta	7782067	The human archain gene, ARCN1, has highly conserved homologs in rice and Drosophila.

Q12476	AIR2_YEAST	Protein AIR2	15828860	A new yeast poly(A) polymerase complex involved in RNA quality control.

P51553	IDH3G_HUMAN	Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial	9286695	Genomic organization of two novel genes on human Xq28: compact head to head arrangement of IDH gamma and TRAP delta is conserved in rat and mouse.

Q06141	REG3A_HUMAN	Regenerating islet-derived protein 3-alpha	1325291	A novel gene (HIP) activated in human primary liver cancer.

Q90WJ8	AJL2_ANGJA	Lactose-binding lectin l-2	11959866	Primary structure and characteristics of a lectin from skin mucus of the Japanese eel Anguilla japonica.

Q11182	VPS16_CAEEL	Vacuolar protein sorting-associated protein 16 homolog	15843430	Genetic analysis of lysosomal trafficking in Caenorhabditis elegans.

Q9Y286	SIGL7_HUMAN	Sialic acid-binding Ig-like lectin 7	10499918	Identification and molecular cloning of p75/AIRM1, a novel member of the sialoadhesin family that functions as an inhibitory receptor in human natural killer cells.

P00739	HPTR_HUMAN	Haptoglobin-related protein	2987228	Nucleotide sequence of the haptoglobin and haptoglobin-related gene pair. The haptoglobin-related gene contains a retrovirus-like element.

Q6NUQ1	RINT1_HUMAN	RAD50-interacting protein 1	15272311	Involvement of BNIP1 in apoptosis and endoplasmic reticulum membrane fusion.

Q13261	I15RA_HUMAN	Interleukin-15 receptor subunit alpha	8530383	Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes.

P63177	RLMB_ECOLI	23S rRNA (guanosine-2'-O-)-methyltransferase rlmB	11698387	The rlmB gene is essential for formation of Gm2251 in 23S rRNA but not for ribosome maturation in Escherichia coli.

Q8R456	OPN4_RAT	Melanopsin	11834834	Melanopsin-containing retinal ganglion cells: architecture, projections, and intrinsic photosensitivity.

Q9P1U1	ARP3B_HUMAN	Actin-related protein 3B	17353931	Large-scale mapping of human protein-protein interactions by mass spectrometry.

Q91ZP3	LPIN1_MOUSE	Phosphatidate phosphatase LPIN1	16950137	Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway.

Q9UBS8	RNF14_HUMAN	E3 ubiquitin-protein ligase RNF14	10085091	Cloning and characterization of human prostate coactivator ARA54, a novel protein that associates with the androgen receptor.

Q9BYM8	UB7I3_HUMAN	RanBP-type and C3HC4-type zinc finger-containing protein 1	12629548	Identification of the ubiquitin-protein ligase that recognizes oxidized IRP2.

Q9WTR2	M3K6_MOUSE	Mitogen-activated protein kinase kinase kinase 6	17210579	Apoptosis signal-regulating kinase (ASK) 2 functions as a mitogen- activated protein kinase kinase kinase in a heteromeric complex with ASK1.

P32191	GPDM_YEAST	Glycerol-3-phosphate dehydrogenase, mitochondrial	8256521	GUT2, a gene for mitochondrial glycerol 3-phosphate dehydrogenase of Saccharomyces cerevisiae.

P11715	CP17A_RAT	Steroid 17-alpha-hydroxylase/17,20 lyase	7702752	Transcriptional regulation of rat cytochrome P450c17 expression in mouse Leydig MA-10 and adrenal Y-1 cells: identification of a single protein that mediates both basal and cAMP-induced activities.

P13861	KAP2_HUMAN	cAMP-dependent protein kinase type II-alpha regulatory subunit	9003463	Molecular cloning, upstream sequence and promoter studies of the human gene for the regulatory subunit RII alpha of cAMP-dependent protein kinase.

Q9Y7S2	YQO3_SCHPO	UPF0612 protein C569.003	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q91ZK4	DMBX1_MOUSE	Diencephalon/mesencephalon homeobox protein 1	12055180	Identification, tissue expression, and functional characterization of Otx3, a novel member of the Otx family.

Q9BV73	CP250_HUMAN	Centrosome-associated protein CEP250	12140259	The mechanism regulating the dissociation of the centrosomal protein C-Nap1 from mitotic spindle poles.

P41212	ETV6_HUMAN	Transcription factor ETV6	7761424	Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia.

O36019	ATG13_SCHPO	Autophagy protein 13	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

P83961	BNCB_BENHI	Beta-benincasin	12576080	Purification and characterization of alpha- and beta-benincasins, arginine/glutamate-rich peptides with translation-inhibiting activity from wax gourd seeds.

Q0VDD7	CS057_HUMAN	Uncharacterized protein C19orf57	8228263	Identification of human pre-T/NK cell-associated genes.

Q84JK2	FD_ARATH	Protein FD	16099979	FD, a bZIP protein mediating signals from the floral pathway integrator FT at the shoot apex.

P31224	ACRB_ECOLI	Acriflavine resistance protein B	10920254	Molecular construction of a multidrug exporter system, AcrAB: molecular interaction between AcrA and AcrB, and cleavage of the N- terminal signal sequence of AcrA.

Q13576	IQGA2_HUMAN	Ras GTPase-activating-like protein IQGAP2	8756646	The Ras GTPase-activating-protein-related human protein IQGAP2 harbors a potential actin binding domain and interacts with calmodulin and Rho family GTPases.

Q9S851	NAC31_ARATH	Protein CUP-SHAPED COTYLEDON 3	17122068	Arabidopsis CUP-SHAPED COTYLEDON3 regulates postembryonic shoot meristem and organ boundary formation.

O88470	FOXL2_MOUSE	Forkhead box protein L2	9620855	Multistep signaling requirements for pituitary organogenesis in vivo.

O74473	CDC11_SCHPO	Septation initiation network scaffold protein cdc11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8IN44	TOTA_DROME	Protein Turandot A	11409894	A family of Turandot-related genes in the humoral stress response of Drosophila.

P55197	AF10_HUMAN	Protein AF-10	17868029	AF10-dependent transcription is enhanced by its interaction with FLRG.

Q9FPN7	AGL31_ARATH	Agamous-like MADS-box protein AGL31	12724541	Analysis of the Arabidopsis MADS AFFECTING FLOWERING gene family: MAF2 prevents vernalization by short periods of cold.

P51094	UFOG_VITVI	Anthocyanidin 3-O-glucosyltransferase 2	16482224	Structure of a flavonoid glucosyltransferase reveals the basis for plant natural product modification.

P0A9Q5	ACCD_ECOLI	Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta	19965770	A tale of two functions: enzymatic activity and translational repression by carboxyltransferase.

Q9SX77	UMP6_ARATH	Uncharacterized protein At1g47420, mitochondrial	11743114	Proteomic approach to identify novel mitochondrial proteins in Arabidopsis.

P18850	ATF6A_HUMAN	Cyclic AMP-dependent transcription factor ATF-6 alpha	9837962	Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins; involvement of basic-leucine zipper transcription factors.

Q9M8K6	MUTE_ARATH	Transcription factor MUTE	17183267	Termination of asymmetric cell division and differentiation of stomata.

Q9Y5X1	SNX9_HUMAN	Sorting nexin-9	20491914	The E3 ubiquitin ligase Itch regulates sorting nexin 9 through an unconventional substrate recognition domain.

Q20745	UNC84_CAEEL	Nuclear migration and anchoring protein unc-84	11748140	unc-83 encodes a novel component of the nuclear envelope and is essential for proper nuclear migration.

Q9Z329	ITPR2_MOUSE	Inositol 1,4,5-trisphosphate receptor type 2	8063813	Determination of relative amounts of inositol trisphosphate receptor mRNA isoforms by ratio polymerase chain reaction.

P70658	CXCR4_MOUSE	C-X-C chemokine receptor type 4	9634238	Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development.

Q9BYF1	ACE2_HUMAN	Angiotensin-converting enzyme 2	10924499	A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase.

P42127	ASIP_HUMAN	Agouti-signaling protein	7937887	Molecular structure and chromosomal mapping of the human homolog of the agouti gene.

Q9P1T7	MDFIC_HUMAN	MyoD family inhibitor domain-containing protein	12192039	I-mfa domain proteins interact with Axin and affect its regulation of the Wnt and c-Jun N-terminal kinase signaling pathways.

P47047	MTR4_YEAST	ATP-dependent RNA helicase DOB1	9463390	Dob1p (Mtr4p) is a putative ATP-dependent RNA helicase required for the 3' end formation of 5.8S rRNA in Saccharomyces cerevisiae.

P30620	PSO2_YEAST	DNA cross-link repair protein PSO2/SNM1	1736091	Molecular structure of the DNA cross-link repair gene SNM1 (PSO2) of the yeast Saccharomyces cerevisiae.

A2AUU0	METL8_MOUSE	Methyltransferase-like protein 8	15992539	TIPs are tension-responsive proteins involved in myogenic versus adipogenic differentiation.

Q91619	NODAL_XENLA	Nodal homolog	16281170	Xenopus nodal related-1 is indispensable only for left-right axis determination.

Q9JHW5	VAMP7_RAT	Vesicle-associated membrane protein 7	15133481	Combinatorial SNARE complexes with VAMP7 or VAMP8 define different late endocytic fusion events.

O14745	NHRF1_HUMAN	Na(+)/H(+) exchange regulatory cofactor NHE-RF1	9430655	NHE-RF, a regulatory cofactor for Na(+)-H+ exchange, is a common interactor for merlin and ERM (MERM) proteins.

P24723	KPCL_HUMAN	Protein kinase C eta type	15632189	Translocation of diacylglycerol kinase theta from cytosol to plasma membrane in response to activation of G protein-coupled receptors and protein kinase C.

Q6TEM9	MYLIA_DANRE	E3 ubiquitin-protein ligase MYLIP-A	18248225	Zebrafish Mir antagonizes Frizzled 7-induced gastrulation defects.

P0A9F1	MNTR_ECOLI	Transcriptional regulator mntR	11466284	Dual repression by Fe(2+)-Fur and Mn(2+)-MntR of the mntH gene, encoding an NRAMP-like Mn(2+) transporter in Escherichia coli.

Q9W5U2	CHIT3_DROME	Probable chitinase 3	9662472	Chitinases are a multi-gene family in Aedes, Anopheles and Drosophila.

P34218	SAS3_YEAST	Histone acetyltransferase SAS3	10817755	The something about silencing protein, Sas3, is the catalytic subunit of NuA3, a yTAF(II)30-containing HAT complex that interacts with the Spt16 subunit of the yeast CP (Cdc68/Pob3)-FACT complex.

Q96EB6	SIRT1_HUMAN	NAD-dependent deacetylase sirtuin-1	18485871	Epigenetic control of rDNA loci in response to intracellular energy status.

P43561	FET5_YEAST	Iron transport multicopper oxidase FET5	10608875	The iron transporter Fth1p forms a complex with the Fet5 iron oxidase and resides on the vacuolar membrane.

Q07084	SSK1_YEAST	Osomolarity two-component system protein SSK1	8183345	A two-component system that regulates an osmosensing MAP kinase cascade in yeast.

Q8BYH0	DRGX_MOUSE	Dorsal root ganglia homeobox protein	14985445	DRAGON: a member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties.

P51142	DVL2_XENLA	Segment polarity protein dishevelled homolog DVL-2	11970895	Dapper, a Dishevelled-associated antagonist of beta-catenin and JNK signaling, is required for notochord formation.

Q13643	FHL3_HUMAN	Four and a half LIM domains protein 3	10049693	The LIM proteins FHL1 and FHL3 are expressed differently in skeletal muscle.

P82869	CYP37_ARATH	Peptidyl-prolyl cis-trans isomerase CYP37, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q09733	GEF2_SCHPO	Rho guanine nucleotide exchange factor gef2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O74957	AGO1_SCHPO	Protein argonaute	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q09898	SID2_SCHPO	Serine/threonine-protein kinase sid2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O14098	CTK1_SCHPO	CTD kinase subunit alpha	15537703	The nuclear kinase Lsk1p positively regulates the septation initiation network and promotes the successful completion of cytokinesis in response to perturbation of the actomyosin ring in Schizosaccharomyces pombe.

P38326	SWC5_YEAST	SWR1-complex protein 5	14645854	ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex.

Q08732	HRK1_YEAST	Serine/threonine-protein kinase HRK1	11003661	Regulation of yeast H(+)-ATPase by protein kinases belonging to a family dedicated to activation of plasma membrane transporters.

Q8C7U7	GALT6_MOUSE	Polypeptide N-acetylgalactosaminyltransferase 6	10464263	Cloning and characterization of a close homologue of human UDP-N- acetyl--D-galactosamine:polypeptide N-acetylgalactosaminyltransferase- T3, designated GalNAc-T6. Evidence for genetic but not functional redundancy.

P32419	MDHP_YEAST	Malate dehydrogenase, peroxisomal	1447211	Isolation and characterization of the yeast gene encoding the MDH3 isozyme of malate dehydrogenase.

Q9QYB1	CLIC4_MOUSE	Chloride intracellular channel protein 4	17636002	CLIC4 mediates and is required for Ca2+-induced keratinocyte differentiation.

Q9DBH0	WWP2_MOUSE	NEDD4-like E3 ubiquitin-protein ligase WWP2	19997087	Wwp2 mediates Oct4 ubiquitination and its own auto-ubiquitination in a dosage-dependent manner.

P38352	SAF1_YEAST	SCF-associated factor 1	19882662	Remodeling of the SCF complex-mediated ubiquitination system by compositional alteration of incorporated F-box proteins.

Q16584	M3K11_HUMAN	Mitogen-activated protein kinase kinase kinase 11	8195146	Identification and characterization of SPRK, a novel src-homology 3 domain-containing proline-rich kinase with serine/threonine kinase activity.

Q9ESX5	DKC1_MOUSE	H/ACA ribonucleoprotein complex subunit 4	10903840	Gene structure and expression of the mouse dyskeratosis congenita gene, dkc1.

P38418	LOX2_ARATH	Lipoxygenase 2, chloroplastic	16207701	The oligomeric stromal proteome of Arabidopsis thaliana chloroplasts.

O59697	PPK25_SCHPO	Serine/threonine-protein kinase ppk25	15821139	Systematic deletion analysis of fission yeast protein kinases.

O15245	S22A1_HUMAN	Solute carrier family 22 member 1	9187257	Cloning and functional expression of a human liver organic cation transporter.

Q04952	FKS3_YEAST	1,3-beta-glucan synthase component FKS3	17158736	Homologous subunits of 1,3-beta-glucan synthase are important for spore wall assembly in Saccharomyces cerevisiae.

Q96Q15	SMG1_HUMAN	Serine/threonine-protein kinase SMG1	14636577	Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7.

P24053	NMBR_RAT	Neuromedin-B receptor	1848080	cDNA cloning, characterization, and brain region-specific expression of a neuromedin-B-preferring bombesin receptor.

P55260	ANXA4_RAT	Annexin A4	12020832	Cloning and characterization of ZAP36, an annexin-like, zymogen granule membrane associated protein, in exocrine pancreas.

Q63430	CSDC2_RAT	Cold shock domain-containing protein C2	8573167	PIPPin, a putative RNA-binding protein specifically expressed in the rat brain.

Q9UTK4	NU189_SCHPO	Nucleoporin nup189	15116432	Identification of genes encoding putative nucleoporins and transport factors in the fission yeast Schizosaccharomyces pombe: a deletion analysis.

P15516	HIS3_HUMAN	Histatin-3	3286634	Histatins, a novel family of histidine-rich proteins in human parotid secretion. Isolation, characterization, primary structure, and fungistatic effects on Candida albicans.

Q9Y2T6	GPR55_HUMAN	G-protein coupled receptor 55	9931487	Identification and cloning of three novel human G protein-coupled receptor genes GPR52, PsiGPR53 and GPR55: GPR55 is extensively expressed in human brain.

Q01064	PDE1B_HUMAN	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	9419816	Identification and characterisation of a human calmodulin-stimulated phosphodiesterase PDE1B1.

P35900	K1C20_HUMAN	Keratin, type I cytoskeletal 20	8359595	The human gene encoding cytokeratin 20 and its expression during fetal development and in gastrointestinal carcinomas.

Q12086	DIN7_YEAST	DNA damage-inducible protein DIN7	9079876	Characterization of a novel DNA damage-inducible gene of Saccharomyces cerevisiae, DIN7, which is a structural homolog of the RAD2 and RAD27 DNA repair genes.

Q9SFD8	NFYB9_ARATH	Nuclear transcription factor Y subunit B-9	9657152	Arabidopsis LEAFY COTYLEDON1 is sufficient to induce embryo development in vegetative cells.

Q9QYS9	QKI_MOUSE	Protein quaking	14706070	Defective smooth muscle development in qkI-deficient mice.

P43568	CAK1_YEAST	Serine/threonine-protein kinase CAK1	8752210	The Cdk-activating kinase (CAK) from budding yeast.

Q12178	FCY1_YEAST	Cytosine deaminase	9000374	Characterization of the Saccharomyces cerevisiae FCY1 gene encoding cytosine deaminase and its homologue FCA1 of Candida albicans.

Q8N5P1	ZC3H8_HUMAN	Zinc finger CCCH domain-containing protein 8	12153508	Regulation of thymocyte homeostasis by Fliz1.

Q94BM7	SPA4_ARATH	Protein SPA1-RELATED 4	16854975	Arabidopsis SPA proteins regulate photoperiodic flowering and interact with the floral inducer CONSTANS to regulate its stability.

Q9C7S7	ERO1_ARATH	Endoplasmic oxidoreductin-1	13678526	Cloning and initial characterization of the Arabidopsis thaliana endoplasmic reticulum oxidoreductins.

P08650	CO5_RAT	Complement C5	7987212	Primary structure and functional characterization of rat C5a: an anaphylatoxin with unusually high potency.

Q9Y5Y2	NUBP2_HUMAN	Cytosolic Fe-S cluster assembly factor NUBP2	10486206	Two novel mouse genes -- Nubp2, mapped to the T-complex on chromosome 17, and Nubp1, mapped to chromosome 16 -- establish a new gene family of nucleotide-binding proteins in eukaryotes.

Q8NFR3	SSPTB_HUMAN	Small subunit of serine palmitoyltransferase B	19416851	Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities.

P48813	GNP1_YEAST	High-affinity glutamine permease	10654085	Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae.

Q7KZ85	SPT6H_HUMAN	Transcription elongation factor SPT6	8786132	Identification and analysis of the human and murine putative chromatin structure regulator SUPT6H and Supt6h.

P35289	RAB15_RAT	Ras-related protein Rab-15	1313420	Rab15, a novel low molecular weight GTP-binding protein specifically expressed in rat brain.

P38435	VKGC_HUMAN	Vitamin K-dependent gamma-carboxylase	1749935	Cloning and expression of the cDNA for human gamma-glutamyl carboxylase.

P28037	FTHFD_RAT	10-formyltetrahydrofolate dehydrogenase	14729668	The crystal structure of the hydrolase domain of 10- formyltetrahydrofolate dehydrogenase: mechanism of hydrolysis and its interplay with the dehydrogenase domain.

Q12805	FBLN3_HUMAN	EGF-containing fibulin-like extracellular matrix protein 1	10369267	A single EFEMP1 mutation associated with both malattia Leventinese and Doyne honeycomb retinal dystrophy.

Q03655	GAS3_YEAST	Probable 1,3-beta-glucanosyltransferase GAS3	15781460	Comprehensive proteomic analysis of Saccharomyces cerevisiae cell walls: identification of proteins covalently attached via glycosylphosphatidylinositol remnants or mild alkali-sensitive linkages.

Q95RV2	CAV_DROME	Telomere-binding protein cav	11408576	Drosophila heterochromatin protein 1 (HP1)/origin recognition complex (ORC) protein is associated with HP1 and ORC and functions in heterochromatin-induced silencing.

Q9USK4	CWF20_SCHPO	Cell cycle control protein cwf20	11884590	Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

Q15486	GUSP1_HUMAN	Putative beta-glucuronidase-like protein SMA3	7977382	Complex repetitive arrangements of gene sequence in the candidate region of the spinal musculuar atropy gene in 5q13.

P32121	ARRB2_HUMAN	Beta-arrestin-2	18604210	An essential function for beta-arrestin 2 in the inhibitory signaling of natural killer cells.

P49817	CAV1_MOUSE	Caveolin-1	10816572	Caveolin-1 expression inhibits Wnt/beta-catenin/Lef-1 signaling by recruiting beta-catenin to caveolae membrane domains.

Q7X9V3	NSI_ARATH	Acetyltransferase NSI	12837950	A novel Arabidopsis acetyltransferase interacts with the geminivirus movement protein NSP.

Q5N800	NYC1_ORYSJ	Probable chlorophyll(ide) b reductase NYC1, chloroplastic	17416733	Rice NON-YELLOW COLORING1 is involved in light-harvesting complex II and grana degradation during leaf senescence.

Q1JQ73	ELV1A_XENLA	ELAV-like protein 1-A	7969126	Further analysis of cytoplasmic polyadenylation in Xenopus embryos and identification of embryonic cytoplasmic polyadenylation element- binding proteins.

P75966	RLUE_ECOLI	Ribosomal large subunit pseudouridine synthase E	11720289	Identification and site of action of the remaining four putative pseudouridine synthases in Escherichia coli.

P53871	DUG3_YEAST	Probable glutamine amidotransferase DUG3	14562095	Global analysis of protein localization in budding yeast.

O14786	NRP1_HUMAN	Neuropilin-1	9529250	Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor.

O15111	IKKA_HUMAN	Inhibitor of nuclear factor kappa-B kinase subunit alpha	16177806	Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus.

Q12962	TAF10_HUMAN	Transcription initiation factor TFIID subunit 10	18206972	A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing.

O15105	SMAD7_HUMAN	Mothers against decapentaplegic homolog 7	16601693	Axin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia.

O94308	CSN1_SCHPO	COP9 signalosome complex subunit 1	11854407	Deletion mutants in COP9/signalosome subunits in fission yeast Schizosaccharomyces pombe display distinct phenotypes.

Q9VI93	RN_DROME	Zinc finger protein rotund	17428824	Nab controls the activity of the zinc-finger transcription factors Squeeze and Rotund in Drosophila development.

Q9W4C5	NAAT1_DROME	Sodium-dependent nutrient amino acid transporter 1	18718864	The invertebrate B(0) system transporter, D. melanogaster NAT1, has unique d-amino acid affinity and mediates gut and brain functions.

P79051	RHP16_SCHPO	ATP-dependent helicase rhp16	10446227	Characterization of the rhp7(+) and rhp16(+) genes in Schizosaccharomyces pombe.

Q8VZG8	Y4885_ARATH	Probable LRR receptor-like serine/threonine-protein kinase At4g08850	17644812	A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome.

Q9TZM3	LRK1_CAEEL	Leucine-rich repeat serine/threonine-protein kinase 1	19251702	Caenorhabditits elegans LRK-1 and PINK-1 Act Antagonistically in Stress Response and Neurite Outgrowth.

P49368	TCPG_HUMAN	T-complex protein 1 subunit gamma	8573069	Cloning, structure and mRNA expression of human Cctg, which encodes the chaperonin subunit CCT gamma.

P36075	CUE2_YEAST	Ubiquitin-binding protein CUE2	12787503	Solution structure of a CUE-ubiquitin complex reveals a conserved mode of ubiquitin binding.

Q12884	SEPR_HUMAN	Seprase	9247085	Molecular cloning of seprase: a serine integral membrane protease from human melanoma.

P47887	OR1E2_HUMAN	Olfactory receptor 1E2	8004088	Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire.

Q9DBL9	ABHD5_MOUSE	1-acylglycerol-3-phosphate O-acyltransferase ABHD5	16679289	Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome.

Q9SAK4	SSDH_ARATH	Succinate-semialdehyde dehydrogenase, mitochondrial	12740438	Mitochondrial succinic-semialdehyde dehydrogenase of the gamma- aminobutyrate shunt is required to restrict levels of reactive oxygen intermediates in plants.

Q9D2N4	DTNA_MOUSE	Dystrobrevin alpha	11316798	Dysbindin, a novel coiled-coil-containing protein that interacts with the dystrobrevins in muscle and brain.

Q9Y646	PGCP_HUMAN	Plasma glutamate carboxypeptidase	10206990	Purification, cDNA cloning, and expression of a new human blood plasma glutamate carboxypeptidase homologous to N-acetyl-aspartyl- alpha-glutamate carboxypeptidase/prostate-specific membrane antigen.

P20839	IMDH1_HUMAN	Inosine-5'-monophosphate dehydrogenase 1	1969416	Two distinct cDNAs for human IMP dehydrogenase.

P52298	NCBP2_HUMAN	Nuclear cap-binding protein subunit 2	7478990	Identification of the factors that interact with NCBP, an 80 kDa nuclear cap binding protein.

P55863	SOX3A_XENLA	Transcription factor Sox-3-A	14522872	The beta-catenin/VegT-regulated early zygotic gene Xnr5 is a direct target of SOX3 regulation.

O42889	YBN5_SCHPO	Uncharacterized protein C8E4.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P15920	VPP2_MOUSE	V-type proton ATPase 116 kDa subunit a isoform 2	16415858	V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway.

O16000	STX1A_CAEEL	Syntaxin-1A homolog	9442061	Functional properties of the unc-64 gene encoding a Caenorhabditis elegans syntaxin.

Q9U6M1	JBP1_LEITA	Thymine dioxygenase JBP1	17389644	The protein that binds to DNA base J in trypanosomatids has features of a thymidine hydroxylase.

Q9CQF0	RM11_MOUSE	39S ribosomal protein L11, mitochondrial	11279069	Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria.

P53838	BOR1_YEAST	Boron transporter 1	16923078	Roles of BOR1, DUR3, and FPS1 in boron transport and tolerance in Saccharomyces cerevisiae.

P62837	UB2D2_HUMAN	Ubiquitin-conjugating enzyme E2 D2	20061386	The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.

P40465	CSM2_YEAST	Chromosome segregation in meiosis protein 2	11470404	A screen for genes required for meiosis and spore formation based on whole-genome expression.

Q9LVM5	TTHL_ARATH	Uric acid degradation bifunctional protein TTL	15319482	The Arabidopsis transthyretin-like protein is a potential substrate of BRASSINOSTEROID-INSENSITIVE 1.

Q91ZV4	MOGT1_MOUSE	2-acylglycerol O-acyltransferase 1	12077311	Identification of a gene encoding MGAT1, a monoacylglycerol acyltransferase.

O60145	PPK23_SCHPO	Serine/threonine-protein kinase ppk23	15821139	Systematic deletion analysis of fission yeast protein kinases.

Q8N5Y2	MS3L1_HUMAN	Male-specific lethal 3 homolog	10395802	Characterization of a novel chromo domain gene in Xp22.3 with homology to Drosophila msl-3.

Q9FHW7	SKP1B_ARATH	SKP1-like protein 1B	19962994	PAH-domain-specific interactions of the Arabidopsis transcription coregulator SIN3-LIKE1 (SNL1) with telomere-binding protein 1 and ALWAYS EARLY2 Myb-DNA binding factors.

P21784	RAG2_MOUSE	V(D)J recombination-activating protein 2	18025461	The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2.

Q9Y603	ETV7_HUMAN	Transcription factor ETV7	10828014	Identification and characterization of a new human ETS-family transcription factor, TEL2, that is expressed in hematopoietic tissues and can associate with TEL1/ETV6.

Q9VEU5	GCYDB_DROME	Soluble guanylate cyclase 89Db	15159437	Preliminary characterization of two atypical soluble guanylyl cyclases in the central and peripheral nervous system of Drosophila melanogaster.

O94359	YHOC_SCHPO	Uncharacterized RNA-binding protein C428.12c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q2QCI8	MED12_DANRE	Mediator of RNA polymerase II transcription subunit 12	16712834	Zebrafish Trap230/Med12 is required as a coactivator for Sox9- dependent neural crest, cartilage and ear development.

Q7XKC5	IDEFH_ORYSJ	B3 domain-containing protein Os04g0676600	18025467	The transcription factor IDEF1 regulates the response to and tolerance of iron deficiency in plants.

Q12387	NAA25_YEAST	N-terminal acetyltransferase B complex subunit MDM20	12783868	Nat3p and Mdm20p are required for function of yeast NatB Nalpha- terminal acetyltransferase and of actin and tropomyosin.

P83332	TLP1_PRUPE	Thaumatin-like protein 1	11847241	Ethylene-responsive genes are differentially regulated during abscission, organ senescence and wounding in peach (Prunus persica).

Q64602	AADAT_RAT	Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial	7493966	Cloning and functional expression of a soluble form of kynurenine/alpha-aminoadipate aminotransferase from rat kidney.

Q8IN43	TOTC_DROME	Protein Turandot C	11409894	A family of Turandot-related genes in the humoral stress response of Drosophila.

Q12462	PEX11_YEAST	Peroxisomal membrane protein PMP27	7721939	Pmp27 promotes peroxisomal proliferation.

Q9FMV1	UMP7_ARATH	Uncharacterized protein At5g63510, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

O75586	MED6_HUMAN	Mediator of RNA polymerase II transcription subunit 6	10024883	A novel human SRB/MED-containing cofactor complex, SMCC, involved in transcription regulation.

P0A6B7	ISCS_ECOLI	Cysteine desulfurase	10600118	IscS is a sulfurtransferase for the in vitro biosynthesis of 4- thiouridine in Escherichia coli tRNA.

P35128	UBE2N_DROME	Ubiquitin-conjugating enzyme E2 N	8182464	Bendless, a Drosophila gene affecting neuronal connectivity, encodes a ubiquitin-conjugating enzyme homolog.

Q9QZN4	FBX6_MOUSE	F-box only protein 6	12939278	Fbs2 is a new member of the E3 ubiquitin ligase family that recognizes sugar chains.

Q9FNH4	NUD27_ARATH	Nudix hydrolase 27, chloroplastic	18815383	Molecular characterization of organelle-type Nudix hydrolases in Arabidopsis.

Q29016	ACRBP_PIG	Acrosin-binding protein	15955892	The proacrosin binding protein, sp32, is tyrosine phosphorylated during capacitation of pig sperm.

P62993	GRB2_HUMAN	Growth factor receptor-bound protein 2	12359715	Molecular cloning of a novel gene encoding a membrane-associated adaptor protein (LAX) in lymphocyte signaling.

Q9N1R6	BAT1_RABIT	B(0,+)-type amino acid transporter 1	10506149	Cloning and expression of a b(0,+)-like amino acid transporter functioning as a heterodimer with 4F2hc instead of rBAT. A new candidate gene for cystinuria.

P31133	POTF_ECOLI	Putrescine-binding periplasmic protein	8416922	Characteristics of the operon for a putrescine transport system that maps at 19 minutes on the Escherichia coli chromosome.

P01920	DQB1_HUMAN	HLA class II histocompatibility antigen, DQ beta 1 chain	2998758	DO beta: a new beta chain gene in HLA-D with a distinct regulation of expression.

P87131	CYSK2_SCHPO	Cysteine synthase 2	14981292	Characterization of two genes encoding putative cysteine synthase required for cysteine biosynthesis in Schizosaccharomyces pombe.

P54318	LIPR2_RAT	Pancreatic lipase-related protein 2	9822688	Structure and activity of rat pancreatic lipase-related protein 2.

Q9SEI0	WER_ARATH	Transcription factor WER	16207757	The WEREWOLF MYB protein directly regulates CAPRICE transcription during cell fate specification in the Arabidopsis root epidermis.

Q8SYG2	CSN3_DROME	COP9 signalosome complex subunit 3	12737805	The COP9 signalosome promotes degradation of Cyclin E during early Drosophila oogenesis.

Q8X1T0	HAG1_SCHPO	UPF0326 protein hag1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P0A6V5	GLPE_ECOLI	Thiosulfate sulfurtransferase glpE	10735872	Characterization of a 12-kilodalton rhodanese encoded by glpE of Escherichia coli and its interaction with thioredoxin.

P77510	DPIB_ECOLI	Sensor histidine kinase DpiB	19202292	Characterization of CitA-CitB signal transduction activating genes involved in anaerobic citrate catabolism in Escherichia coli.

P84808	CRV23_NAJKA	Cysteine-rich venom protein 23	15670767	Cobra venom contains a pool of cysteine-rich secretory proteins.

O00291	HIP1_HUMAN	Huntingtin-interacting protein 1	15533940	Huntingtin-interacting protein 1 (Hip1) and Hip1-related protein (Hip1R) bind the conserved sequence of clathrin light chains and thereby influence clathrin assembly in vitro and actin distribution in vivo.

P04551	CDK1_SCHPO	Cell division control protein 2	11163211	The spike of S phase cyclin Cig2 expression at the G1-S border in fission yeast requires both APC and SCF ubiquitin ligases.

Q91WL8	WWOX_MOUSE	WW domain-containing oxidoreductase	11058590	Hyaluronidase induction of a WW domain-containing oxidoreductase that enhances tumor necrosis factor cytotoxicity.

O88923	LPHN2_RAT	Latrophilin-2	10026162	A novel ubiquitously expressed alpha-latrotoxin receptor is a member of the CIRL family of G-protein-coupled receptors.

Q05753	AKRP_ARATH	Ankyrin repeat domain-containing protein, chloroplastic	17092312	AKRP and EMB506 are two ankyrin repeat proteins essential for plastid differentiation and plant development in Arabidopsis.

Q23SI8	TTLL1_TETTH	Probable alpha-tubulin polyglutamylase Ttll1	15890843	Tubulin polyglutamylase enzymes are members of the TTL domain protein family.

Q13618	CUL3_HUMAN	Cullin-3	12609982	TIP120A associates with cullins and modulates ubiquitin ligase activity.

Q55AR3	TBG_DICDI	Tubulin gamma chain	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

Q91WK2	EIF3H_MOUSE	Eukaryotic translation initiation factor 3 subunit H	17581632	Reconstitution reveals the functional core of mammalian eIF3.

O54784	DAPK3_MOUSE	Death-associated protein kinase 3	9488481	ZIP kinase, a novel serine/threonine kinase which mediates apoptosis.

Q9XWD6	CED1_CAEEL	Cell death abnormality protein 1	11163239	CED-1 is a transmembrane receptor that mediates cell corpse engulfment in C. elegans.

Q86DA5	SARM1_CAEEL	Sterile alpha and TIR motif-containing protein tir-1	15048112	TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM.

Q64337	SQSTM_MOUSE	Sequestosome-1	10458914	Cloning, expression profile, and genomic organization of the mouse STAP/A170 gene.

P16521	EF3A_YEAST	Elongation factor 3A	9553076	The N-terminus of eukaryotic translation elongation factor 3 interacts with 18 S rRNA and 80 S ribosomes.

Q9NPH5	NOX4_HUMAN	NADPH oxidase 4	10869423	Identification of renox, an NAD(P)H oxidase in kidney.

Q8BZZ3	WWP1_MOUSE	NEDD4-like E3 ubiquitin-protein ligase WWP1	11375995	Lung Krueppel-like factor contains an autoinhibitory domain that regulates its transcriptional activation by binding WWP1, an E3 ubiquitin ligase.

Q8IXJ6	SIRT2_HUMAN	NAD-dependent deacetylase sirtuin-2	12697818	Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle.

P42081	CD86_HUMAN	T-lymphocyte activation antigen CD86	7694363	Cloning of B7-2: a CTLA-4 counter-receptor that costimulates human T cell proliferation.

O60477	DBC1_HUMAN	Deleted in bladder cancer protein 1	11420708	Negative regulation of G(1)/S transition by the candidate bladder tumour suppressor gene DBCCR1.

O13629	LPLA_SCHPO	Putative lipoate-protein ligase A	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P13647	K2C5_HUMAN	Keratin, type II cytoskeletal 5	15731013	Identification of trichoplein, a novel keratin filament-binding protein.

Q9LZR8	Y5370_ARATH	PAN domain-containing protein At5g03700	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P38398	BRCA1_HUMAN	Breast cancer type 1 susceptibility protein	14976165	BRCA1:BARD1 induces the formation of conjugated ubiquitin structures, dependent on K6 of ubiquitin, in cells during DNA replication and repair.

P34358	CED7_CAEEL	ABC transporter ced-7	9635425	The C. elegans cell corpse engulfment gene ced-7 encodes a protein similar to ABC transporters.

P53906	YNO6_YEAST	Uncharacterized protein YNL146W	14562095	Global analysis of protein localization in budding yeast.

Q80TV8	CLAP1_MOUSE	CLIP-associating protein 1	11290329	Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts.

Q8R511	FNBP1_RAT	Formin-binding protein 1	14732713	Identification of splicing variants of Rapostlin, a novel RND2 effector that interacts with neural Wiskott-Aldrich syndrome protein and induces neurite branching.

O75923	DYSF_HUMAN	Dysferlin	11959863	Calcium-sensitive phospholipid binding properties of normal and mutant ferlin C2 domains.

P17178	CP27A_RAT	Sterol 26-hydroxylase, mitochondrial	2175615	A cDNA encoding a rat mitochondrial cytochrome P450 catalyzing both the 26-hydroxylation of cholesterol and 25-hydroxylation of vitamin D3: gonadotropic regulation of the cognate mRNA in ovaries.

P52917	VPS4_YEAST	Vacuolar protein sorting-associated protein 4	16505166	Recycling of ESCRTs by the AAA-ATPase Vps4 is regulated by a conserved VSL region in Vta1.

Q9H267	VP33B_HUMAN	Vacuolar protein sorting-associated protein 33B	15052268	Mutations in VPS33B, encoding a regulator of SNARE-dependent membrane fusion, cause arthrogryposis-renal dysfunction-cholestasis (ARC) syndrome.

P08425	SYFM_YEAST	Phenylalanyl-tRNA synthetase, mitochondrial	1924298	Evolution of aminoacyl-tRNA synthetase quaternary structure and activity: Saccharomyces cerevisiae mitochondrial phenylalanyl-tRNA synthetase.

P47081	COX16_YEAST	Cytochrome c oxidase assembly protein COX16, mitochondrial	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Q10160	RMI1_SCHPO	RecQ-mediated genome instability protein 1	15889139	RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex.

P34508	CRN6_CAEEL	Cell death-related nuclease 6	12718884	Functional genomic analysis of apoptotic DNA degradation in C. elegans.

P93836	HPPD_ARATH	4-hydroxyphenylpyruvate dioxygenase	15084729	The crystal structures of Zea mays and Arabidopsis 4- hydroxyphenylpyruvate dioxygenase.

O13856	YEX2_SCHPO	Uncharacterized WD repeat-containing protein C1A6.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P49704	PRP31_YEAST	Pre-mRNA-processing factor 31	10377396	Purification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins.

Q3TDN0	DISP1_MOUSE	Protein dispatched homolog 1	12372301	Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched.

P20674	COX5A_HUMAN	Cytochrome c oxidase subunit 5A, mitochondrial	2853101	Subunit Va of human and bovine cytochrome c oxidase is highly conserved.

O13826	RFP1_SCHPO	E3 ubiquitin-protein ligase complex slx8-rfp subunit rfp1	17762865	SUMO-targeted ubiquitin ligases in genome stability.

Q90260	ASL1B_DANRE	Achaete-scute homolog 1b	15659486	Wnt1 regulates neurogenesis and mediates lateral inhibition of boundary cell specification in the zebrafish hindbrain.

P15791	KCC2D_RAT	Calcium/calmodulin-dependent protein kinase type II subunit delta	18056528	Rad GTPase deficiency leads to cardiac hypertrophy.

Q10573	LIN25_CAEEL	Protein lin-25	9806929	Caenorhabditis elegans lin-25: cellular focus, protein expression and requirement for sur-2 during induction of vulval fates.

Q9HAF1	EAF6_HUMAN	Chromatin modification-related protein MEAF6	14966270	Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans.

P53063	DOM3Z_YEAST	RAT1-interacting protein	10805743	Saccharomyces cerevisiae RAI1 (YGL246c) is homologous to human DOM3Z and encodes a protein that binds the nuclear exoribonuclease Rat1p.

Q09624	LOV1_CAEEL	Location of vulva defective 1	16481400	Casein kinase II and calcineurin modulate TRPP function and ciliary localization.

Q93079	H2B1H_HUMAN	Histone H2B type 1-H	9119399	Human histone gene organization: nonregular arrangement within a large cluster.

Q53T94	TAF1B_HUMAN	TATA box-binding protein-associated factor RNA polymerase I subunit B	7801123	Reconstitution of transcription factor SL1: exclusive binding of TBP by SL1 or TFIID subunits.

P38179	ALG3_YEAST	Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase	8842708	Cloning and characterization of the ALG3 gene of Saccharomyces cerevisiae.

Q08334	I10R2_HUMAN	Interleukin-10 receptor subunit beta	8314576	A new member of the cytokine receptor gene family maps on chromosome 21 at less than 35 kb from IFNAR.

O14350	SWI3_SCHPO	Swi1-interacting protein swi3	15367656	Swi1 and swi3 are components of a replication fork protection complex in fission yeast.

P49761	CLK3_HUMAN	Dual specificity protein kinase CLK3	7990150	Characterization by cDNA cloning of two new human protein kinases. Evidence by sequence comparison of a new family of mammalian protein kinases.

Q9UM19	HPCL4_HUMAN	Hippocalcin-like protein 4	10520747	Isolation of two human cDNAs, HLP3 and HLP4, homologous to the neuron-specific calcium-binding protein genes.

P24000	RL24B_YEAST	60S ribosomal protein L24-B	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q99314	SAS5_YEAST	Something about silencing protein 5	11731479	The yeast SAS (something about silencing) protein complex contains a MYST-type putative acetyltransferase and functions with chromatin assembly factor ASF1.

O13956	TSR1_SCHPO	Ribosome biogenesis protein tsr1 homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q06682	UBX5_YEAST	UBX domain-containing protein 5	15258615	Shp1 and Ubx2 are adaptors of Cdc48 involved in ubiquitin-dependent protein degradation.

Q13509	TBB3_HUMAN	Tubulin beta-3 chain	20074521	Human TUBB3 mutations perturb microtubule dynamics, kinesin interactions, and axon guidance.

P69210	MDTI_ECOLI	Spermidine export protein mdtI	11867724	Rapid topology mapping of Escherichia coli inner-membrane proteins by prediction and PhoA/GFP fusion analysis.

Q14524	SCN5A_HUMAN	Sodium channel protein type 5 subunit alpha	9521325	Genetic basis and molecular mechanism for idiopathic ventricular fibrillation.

Q9SVC6	PUB22_ARATH	E3 ubiquitin-protein ligase PUB22	18771922	Negative regulation of PAMP-triggered immunity by an E3 ubiquitin ligase triplet in Arabidopsis.

P91793	DEFA_AEDAE	Defensin-A	7633471	Insect immunity: isolation of three novel inducible antibacterial defensins from the vector mosquito, Aedes aegypti.

O74326	CID11_SCHPO	Poly(A) RNA polymerase cid11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8BVN3	CTSR4_MOUSE	Cation channel sperm-associated protein 4	16107607	Catsper3 and catsper4 encode two cation channel-like proteins exclusively expressed in the testis.

Q75K18	SRP54_DICDI	Signal recognition particle 54 kDa protein	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q9URY2	ALP7_SCHPO	Microtubule protein alp7	14742702	Interdependency of fission yeast Alp14/TOG and coiled coil protein Alp7 in microtubule localization and bipolar spindle formation.

Q9P4X2	YKV4_SCHPO	Uncharacterized mannosyltransferase C959.04c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8W5S1	CCH11_ARATH	Cyclin-H1-1	16856985	Diverse phosphoregulatory mechanisms controlling cyclin-dependent kinase-activating kinases in Arabidopsis.

O15499	GSC2_HUMAN	Homeobox protein goosecoid-2	9441739	Characterization and mutation analysis of goosecoid-like (GSCL), a homeodomain-containing gene that maps to the critical region for VCFS/DGS on 22q11.

P56589	PEX3_HUMAN	Peroxisomal biogenesis factor 3	10958759	Defective peroxisome membrane synthesis due to mutations in human PEX3 causes Zellweger syndrome, complementation group G.

P61714	RISB_ECOLI	6,7-dimethyl-8-ribityllumazine synthase	8969176	Biosynthesis of riboflavin. Lumazine synthase of Escherichia coli.

Q9VVR1	NOT_DROME	Ubiquitin carboxyl-terminal hydrolase nonstop	11182084	Glial cells mediate target layer selection of retinal axons in the developing visual system of Drosophila.

Q10021	RSP5_CAEEL	Probable splicing factor, arginine/serine-rich 5	10747030	Functional characterization of SR and SR-related genes in Caenorhabditis elegans.

P29371	NK3R_HUMAN	Neuromedin-K receptor	1374246	cDNA sequence and heterologous expression of the human neurokinin-3 receptor.

Q8GTR4	PULA1_ARATH	Pullulanase 1, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

P57775	FBXW4_HUMAN	F-box/WD repeat-containing protein 4	10945468	cDNA cloning and expression analysis of new members of the mammalian F-box protein family.

Q9UBV7	B4GT7_HUMAN	Beta-1,4-galactosyltransferase 7	10506123	Molecular basis for the progeroid variant of Ehlers-Danlos syndrome. Identification and characterization of two mutations in galactosyltransferase I gene.

P40189	IL6RB_HUMAN	Interleukin-6 receptor subunit beta	12829785	Hexameric structure and assembly of the interleukin-6/IL-6 alpha- receptor/gp130 complex.

Q92922	SMRC1_HUMAN	SWI/SNF complex subunit SMARCC1	9891079	Cyclin E associates with BAF155 and BRG1, components of the mammalian SWI-SNF complex, and alters the ability of BRG1 to induce growth arrest.

Q9QYH7	GHRL_RAT	Appetite-regulating hormone	10604470	Ghrelin is a growth-hormone-releasing acylated peptide from stomach.

P06101	CDC37_YEAST	Hsp90 co-chaperone Cdc37	17220467	Cdc37p is required for stress-induced high-osmolarity glycerol and protein kinase C mitogen-activated protein kinase pathway functionality by interaction with Hog1p and Slt2p (Mpk1p).

Q9P212	PLCE1_HUMAN	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon-1	11022047	A novel bifunctional phospholipase C that is regulated by Galpha 12 and stimulates the Ras/mitogen-activated protein kinase pathway.

P70033	NR6A1_XENLA	Nuclear receptor subfamily 6 group A member 1	12729562	The function of Xenopus germ cell nuclear factor (xGCNF) in morphogenetic movements during neurulation.

Q9NRR4	RNC_HUMAN	Ribonuclease 3	15574589	The Drosha-DGCR8 complex in primary microRNA processing.

P53705	BUD4_CANAL	Bud site selection protein BUD4	8552638	Cloning and expression of a gene encoding an integrin-like protein in Candida albicans.

Q12933	TRAF2_HUMAN	TNF receptor-associated factor 2	9153189	ATAR, a novel tumor necrosis factor receptor family member, signals through TRAF2 and TRAF5.

P11233	RALA_HUMAN	Ras-related protein Ral-A	18756269	Distinct roles of RalA and RalB in the progression of cytokinesis are supported by distinct RalGEFs.

Q9ERI5	JMJD6_MOUSE	Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6	14645847	Phosphatidylserine receptor is required for clearance of apoptotic cells.

Q9VEI3	S35B2_DROME	Adenosine 3'-phospho 5'-phosphosulfate transporter 1	12716889	Molecular cloning and identification of 3'-phosphoadenosine 5'- phosphosulfate transporter.

P38064	RM16_YEAST	54S ribosomal protein L16, mitochondrial	9151978	Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae.

P60844	AQPZ_ECOLI	Aquaporin Z	10400575	Visualization of AqpZ-mediated water permeability in Escherichia coli by cryoelectron microscopy.

O80341	EF102_ARATH	Ethylene-responsive transcription factor 5	10715325	Arabidopsis ethylene responsive element binding factors act as transcriptional activators or repressors of GCC box mediated gene expression.

Q43309	1A14_ARATH	1-aminocyclopropane-1-carboxylate synthase 4	20511490	Arabidopsis RING E3 ligase XBAT32 regulates lateral root production through its role in ethylene biosynthesis.

P32354	MCM10_YEAST	Minichromosome maintenance protein 10	11168584	Interactions between Mcm10p and other replication factors are required for proper initiation and elongation of chromosomal DNA replication in Saccharomyces cerevisiae.

Q32SG6	HIRA_MAIZE	Protein HIRA	16243907	Maize rough sheath2 and its Arabidopsis orthologue ASYMMETRIC LEAVES1 interact with HIRA, a predicted histone chaperone, to maintain knox gene silencing and determinacy during organogenesis.

Q12393	GEP5_YEAST	Genetic interactor of prohibitin 5, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

Q9LXV2	MYB46_ARATH	Transcription factor MYB46	16463103	The MYB transcription factor superfamily of Arabidopsis: expression analysis and phylogenetic comparison with the rice MYB family.

O94586	HNT1_SCHPO	Hit family protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P39346	IDND_ECOLI	L-idonate 5-dehydrogenase	9658018	Sequence analysis of the GntII (subsidiary) system for gluconate metabolism reveals a novel pathway for L-idonic acid catabolism in Escherichia coli.

Q02891	MCFS1_YEAST	Medium-chain fatty acid ethyl ester synthase/esterase 1	16361250	The Saccharomyces cerevisiae EHT1 and EEB1 genes encode novel enzymes with medium-chain fatty acid ethyl ester synthesis and hydrolysis capacity.

P68036	UB2L3_HUMAN	Ubiquitin-conjugating enzyme E2 L3	8576257	Cloning of human ubiquitin-conjugating enzymes UbcH6 and UbcH7 (E2- F1) and characterization of their interaction with E6-AP and RSP5.

Q9JKF8	RASD1_RAT	Dexamethasone-induced Ras-related protein 1	18922798	Dexras1 interacts with FE65 to regulate FE65-amyloid precursor protein-dependent transcription.

P25425	PO2F1_MOUSE	POU domain, class 2, transcription factor 1	14729276	Cloning, genomic organization, expression, and effect on beta-casein promoter activity of a novel isoform of the mouse Oct-1 transcription factor.

P22518	CLK1_MOUSE	Dual specificity protein kinase CLK1	1986248	STY, a tyrosine-phosphorylating enzyme with sequence homology to serine/threonine kinases.

Q96UP3	RIF1_SCHPO	Telomere length regulator protein rif1	11676925	spRap1 and spRif1, recruited to telomeres by Taz1, are essential for telomere function in fission yeast.

Q9BUB5	MKNK1_HUMAN	MAP kinase-interacting serine/threonine-protein kinase 1	9155018	MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates.

Q6AT10	IAA15_ORYSJ	Auxin-responsive protein IAA15	16200395	Structure and expression analysis of early auxin-responsive Aux/IAA gene family in rice (Oryza sativa).

P55327	TPD52_HUMAN	Tumor protein D52	8632896	Isolation and characterization of a novel gene expressed in multiple cancers.

Q62172	RBP1_MOUSE	RalA-binding protein 1	9395447	An eps homology (EH) domain protein that binds to the ral-GTPase target, RalBP1.

Q9Y3Q4	HCN4_HUMAN	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4	10228147	Two pacemaker channels from human heart with profoundly different activation kinetics.

P09936	UCHL1_HUMAN	Ubiquitin carboxyl-terminal hydrolase isozyme L1	8639624	Substrate binding and catalysis by ubiquitin C-terminal hydrolases: identification of two active site residues.

Q05123	ARP9_YEAST	Actin-like protein ARP9	12183366	Chromatin remodeling by RSC involves ATP-dependent DNA translocation.

Q9UMR5	PPT2_HUMAN	Lysosomal thioesterase PPT2	10417332	Characterization of a human MHC class III region gene product with S- thioesterase activity.

P18475	TORSO_DROME	Tyrosine-protein kinase receptor torso	2927509	The Drosophila gene torso encodes a putative receptor tyrosine kinase.

Q75Q40	TOM40_RAT	Mitochondrial import receptor subunit TOM40 homolog	10980201	Characterization of rat TOM40, a central component of the preprotein translocase of the mitochondrial outer membrane.

Q7TPB1	TCPD_RAT	T-complex protein 1 subunit delta	12874111	Hereditary sensory neuropathy is caused by a mutation in the delta subunit of the cytosolic chaperonin-containing T-complex peptide-1 (Cct4) gene.

P37639	GADX_ECOLI	HTH-type transcriptional regulator gadX	12446650	Collaborative regulation of Escherichia coli glutamate-dependent acid resistance by two AraC-like regulators, GadX and GadW (YhiW).

O15529	GPR42_HUMAN	G-protein coupled receptor 42	9344866	A cluster of four novel human G protein-coupled receptor genes occurring in close proximity to CD22 gene on chromosome 19q13.1.

Q06143	DIC1_YEAST	Mitochondrial dicarboxylate transporter	9020177	Identification of a novel gene encoding the yeast mitochondrial dicarboxylate transport protein via overexpression, purification, and characterization of its protein product.

A2ALU4	SHRM2_MOUSE	Protein Shroom2	16684770	Differential actin-dependent localization modulates the evolutionarily conserved activity of Shroom family proteins.

P17813	EGLN_HUMAN	Endoglin	8370410	Identification and expression of two forms of the human transforming growth factor-beta-binding protein endoglin with distinct cytoplasmic regions.

P40120	OPGD_ECOLI	Glucans biosynthesis protein D	15175282	Identification of mdoD, an mdoG paralog which encodes a twin- arginine-dependent periplasmic protein that controls osmoregulated periplasmic glucan backbone structures.

Q64346	DUS6_RAT	Dual specificity protein phosphatase 6	8626780	MKP-3, a novel cytosolic protein-tyrosine phosphatase that exemplifies a new class of mitogen-activated protein kinase phosphatase.

P60213	SC49A_TITCA	Toxin Tc48b/Tc49a	15025998	Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

Q96HR8	NAF1_HUMAN	H/ACA ribonucleoprotein complex non-core subunit NAF1	16601202	hNaf1 is required for accumulation of human box H/ACA snoRNPs, scaRNPs, and telomerase.

P38790	HTD2_YEAST	Hydroxyacyl-thioester dehydratase type 2, mitochondrial	15387819	Htd2p/Yhr067p is a yeast 3-hydroxyacyl-ACP dehydratase essential for mitochondrial function and morphology.

Q02455	MLP1_YEAST	Protein MLP1	10085285	Proteins connecting the nuclear pore complex with the nuclear interior.

Q550D5	GTAA_DICDI	Transcription factor stalky	8898200	Identification of the cell fate gene stalky in Dictyostelium.

P25043	PSB7_YEAST	Proteasome component PUP1	9087403	Structure of 20S proteasome from yeast at 2.4-A resolution.

Q9NBX4	RTXE_DROME	Probable RNA-directed DNA polymerase from transposon X-element	11405632	The X element, a novel LINE transposable element from Drosophila melanogaster.

Q8RXX9	ATL6_ARATH	E3 ubiquitin-protein ligase ATL6	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P38830	NDT80_YEAST	Meiosis-specific transcription factor NDT80	8524222	NDT80, a meiosis-specific gene required for exit from pachytene in Saccharomyces cerevisiae.

Q8VDB9	S620A_MOUSE	Sodium- and chloride-dependent transporter XTRP3A	16174864	Luminal kidney and intestine SLC6 amino acid transporters of B0AT- cluster and their tissue distribution in Mus musculus.

Q9VMA3	CUP_DROME	Protein cup	14685270	Drosophila Cup is an eIF4E-binding protein that functions in Smaug- mediated translational repression.

Q9Y7M8	YNTB_SCHPO	Probable RNA exonuclease C9B6.11c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P50995	ANX11_HUMAN	Annexin A11	7508441	The 56K autoantigen is identical to human annexin XI.

Q9VLA2	GCM2_DROME	Transcription factor glial cells missing 2	12167411	gcm2 promotes glial cell differentiation and is required with glial cells missing for macrophage development in Drosophila.

P93829	PRA1D_ARATH	PRA1 family protein D	11725951	Identification of arabidopsis proteins that interact with the cauliflower mosaic virus (CaMV) movement protein.

Q8R5J9	PRAF3_MOUSE	PRA1 family protein 3	12119102	Molecular cloning, gene structure, expression profile and functional characterization of the mouse glutamate transporter (EAAT3) interacting protein GTRAP3-18.

Q08580	PEX27_YEAST	Peroxisomal membrane protein PEX27	14517321	Pex11-related proteins in peroxisome dynamics: a role for the novel peroxin Pex27p in controlling peroxisome size and number in Saccharomyces cerevisiae.

O60729	CC14B_HUMAN	Dual specificity protein phosphatase CDC14B	9367992	A family of putative tumor suppressors is structurally and functionally conserved in humans and yeast.

Q63285	UHMK1_RAT	Serine/threonine-protein kinase Kist	9287318	KIS is a protein kinase with an RNA recognition motif.

Q9NVM4	ANM7_HUMAN	Protein arginine N-methyltransferase 7	15044439	PRMT7 is a member of the protein arginine methyltransferase family with a distinct substrate specificity.

Q9VYX7	PGPSA_DROME	Peptidoglycan-recognition protein SA	11742401	Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein.

Q9P7K5	GIT1_SCHPO	Adenylate cyclase activation protein git1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8IY57	YAF2_HUMAN	YY1-associated factor 2	11593398	Functional interaction of Yaf2 with the central region of MycN.

Q8GSP8	ZYS3_CHLRE	Zygote-specific protein 3	10069826	Characterization of Chlamydomonas reinhardtii zygote-specific cDNAs that encode novel proteins containing ankyrin repeats and WW domains.

Q9Y0V2	TIM9B_CAEEL	Mitochondrial import inner membrane translocase subunit Tim9B	15485840	Defective mitochondrial protein translocation precludes normal Caenorhabditis elegans development.

P39013	END3_YEAST	Actin cytoskeleton-regulatory complex protein END3	8380177	END3 and END4: two mutants defective in receptor-mediated and fluid- phase endocytosis in Saccharomyces cerevisiae.

Q99PG4	RGS18_MOUSE	Regulator of G-protein signaling 18	11042171	Molecular cloning and characterization of a novel regulator of G- protein signaling from mouse hematopoietic stem cells.

Q96DI7	SNR40_HUMAN	U5 small nuclear ribonucleoprotein 40 kDa protein	9774689	The human U5-220kD protein (hPrp8) forms a stable RNA-free complex with several U5-specific proteins, including an RNA unwindase, a homologue of ribosomal elongation factor EF-2, and a novel WD-40 protein.

P35520	CBS_HUMAN	Cystathionine beta-synthase	17087506	Human cystathionine beta-synthase is a target for sumoylation.

P41208	CETN2_HUMAN	Centrin-2	12176356	Centrin-2 is required for centriole duplication in mammalian cells.

Q12016	VPS68_YEAST	Vacuolar protein sorting-associated protein 68	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q62940	NEDD4_RAT	E3 ubiquitin-protein ligase NEDD4	8665844	WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome.

Q2V419	CKB12_ARATH	Cyclin-dependent kinase B1-2	11432958	Identification of novel cyclin-dependent kinases interacting with the CKS1 protein of Arabidopsis.

Q967F4	HMR1_CAEEL	Cadherin-related hmr-1	10952315	Distinct beta-catenins mediate adhesion and signalling functions in C. elegans.

P19388	RPAB1_HUMAN	DNA-directed RNA polymerases I, II, and III subunit RPABC1	9852112	Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.

P63172	DYLT1_HUMAN	Dynein light chain Tctex-type 1	17965411	Interaction of the DYNLT (TCTEX1/RP3) light chains and the intermediate chains reveals novel intersubunit regulation during assembly of the dynein complex.

Q9DA19	CIR1_MOUSE	Corepressor interacting with RBPJ 1	15652350	CIR, a corepressor of CBF1, binds to PAP-1 and effects alternative splicing.

Q9Y230	RUVB2_HUMAN	RuvB-like 2	15960975	Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

P38827	SET1_YEAST	Histone-lysine N-methyltransferase, H3 lysine-4 specific	9988274	Interaction between Set1p and checkpoint protein Mec3p in DNA repair and telomere functions.

P41913	GDS1_YEAST	Protein GDS1	8750239	Nucleotide sequence of the GDS1 gene of Saccharomyces cerevisiae.

Q08477	CP4F3_HUMAN	Leukotriene-B(4) omega-hydroxylase 2	9539102	Human leukotriene B4 omega-hydroxylase (CYP4F3) gene: molecular cloning and chromosomal localization.

O43426	SYNJ1_HUMAN	Synaptojanin-1	9428629	Synaptojanin 1: localization on coated endocytic intermediates in nerve terminals and interaction of its 170 kDa isoform with Eps15.

Q46865	MQSR_ECOLI	Motility quorum-sensing regulator mqsR	16352847	Autoinducer 2 controls biofilm formation in Escherichia coli through a novel motility quorum-sensing regulator (MqsR, B3022).

P51686	CCR9_HUMAN	C-C chemokine receptor type 9	10229797	Identification of the orphan chemokine receptor GPR-9-6 as CCR9, the receptor for the chemokine TECK.

P0A9K9	SLYD_ECOLI	FKBP-type peptidyl-prolyl cis-trans isomerase slyD	9188461	The Escherichia coli SlyD is a metal ion-regulated peptidyl-prolyl cis/trans-isomerase.

Q8IZU9	KIRR3_HUMAN	Kin of IRRE-like protein 3	12424224	NEPH1 defines a novel family of podocin interacting proteins.

Q59EK9	RUN3A_HUMAN	RUN domain-containing protein 3A	9523700	Identification of a specific effector of the small GTP-binding protein Rap2.

P53283	TPO2_YEAST	Polyamine transporter 2	12562762	Localization and function of the yeast multidrug transporter Tpo1p.

Q02804	ARL3_YEAST	ADP-ribosylation factor-like protein 3	15077114	Golgi targeting of ARF-like GTPase Arl3p requires its Nalpha- acetylation and the integral membrane protein Sys1p.

P48740	MASP1_HUMAN	Mannan-binding lectin serine protease 1	11485744	MASP-3 and its association with distinct complexes of the mannan- binding lectin complement activation pathway.

O55203	LDB2_MOUSE	LIM domain-binding protein 2	11882901	Ubiquitination-dependent cofactor exchange on LIM homeodomain transcription factors.

P83852	CBPD_LOPSP	Carboxypeptidase D	10545093	Crystal structure of avian carboxypeptidase D domain II: a prototype for the regulatory metallocarboxypeptidase subfamily.

P32478	HS150_YEAST	Cell wall mannoprotein HSP150	15781460	Comprehensive proteomic analysis of Saccharomyces cerevisiae cell walls: identification of proteins covalently attached via glycosylphosphatidylinositol remnants or mild alkali-sensitive linkages.

Q9P7N6	YIO2_SCHPO	TPR repeat-containing protein P27G11.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P11075	SEC7_YEAST	Protein transport protein SEC7	3042778	SEC7 encodes an unusual, high molecular weight protein required for membrane traffic from the yeast Golgi apparatus.

P21272	CEBPB_RAT	CCAAT/enhancer-binding protein beta	1377818	Molecular cloning of two C/EBP-related proteins that bind to the promoter and the enhancer of the alpha 1-fetoprotein gene. Further analysis of C/EBP beta and C/EBP gamma.

P83279	FAR6_MACRS	FMRFamide-like neuropeptide FLP6	11179812	Three more novel FMRFamide-like neuropeptide sequences from the eyestalk of the giant freshwater prawn Macrobrachium rosenbergii.

P01770	HV309_HUMAN	Ig heavy chain V-III region NIE	826475	The rule of antibody structure. The primary structure of a monoclonal IgG1 immunoglobulin (myeloma protein Nie). III. The chymotryptic peptides of the H-chain, alignment of the tryptic peptides and discussion of the complete structure.

P19013	K2C4_HUMAN	Keratin, type II cytoskeletal 4	2452170	Molecular characterization and expression of the stratification- related cytokeratins 4 and 15.

O43246	CTR4_HUMAN	Cationic amino acid transporter 4	9598310	The gene encoding a cationic amino acid transporter (SLC7A4) maps to the region deleted in the velocardiofacial syndrome.

P43146	DCC_HUMAN	Netrin receptor DCC	8861902	Deleted in Colorectal Cancer (DCC) encodes a netrin receptor.

Q9H9S5	FKRP_HUMAN	Fukutin-related protein	19900540	Mutations alter secretion of fukutin-related protein.

Q9VR07	INE_DROME	Sodium- and chloride-dependent GABA transporter ine	11880499	In vivo properties of the Drosophila inebriated-encoded neurotransmitter transporter.

Q08231	THP1_YEAST	Nuclear mRNA export protein THP1	14718168	Sus1, a functional component of the SAGA histone acetylase complex and the nuclear pore-associated mRNA export machinery.

P80957	BDEF_TACTR	Big defensin	8586631	A novel big defensin identified in horseshoe crab hemocytes: isolation, amino acid sequence, and antibacterial activity.

Q96EP1	CHFR_HUMAN	E3 ubiquitin-protein ligase CHFR	15467728	PML bodies control the nuclear dynamics and function of the CHFR mitotic checkpoint protein.

Q9SUP6	WRK53_ARATH	Probable WRKY transcription factor 53	17369373	The antagonist function of Arabidopsis WRKY53 and ESR/ESP in leaf senescence is modulated by the jasmonic and salicylic acid equilibrium.

Q04549	ARP10_YEAST	Actin-like protein ARP10	16291862	Arp10p is a pointed-end-associated component of yeast dynactin.

P25359	RRP43_YEAST	Exosome complex component RRP43	12364597	Temperature-sensitive mutants of the exosome subunit Rrp43p show a deficiency in mRNA degradation and no longer interact with the exosome.

P34708	TRA1_CAEEL	Sex-determining transformer protein 1	11703944	RNA-Regulated TRA-1 nuclear export controls sexual fate.

O75131	CPNE3_HUMAN	Copine-3	11041869	Characterization of human copine III as a phosphoprotein with associated kinase activity.

P39013	END3_YEAST	Actin cytoskeleton-regulatory complex protein END3	10594004	Pan1p, End3p, and Sla1p, three yeast proteins required for normal cortical actin cytoskeleton organization, associate with each other and play essential roles in cell wall morphogenesis.

Q9Y4X1	UD2A1_HUMAN	UDP-glucuronosyltransferase 2A1	19858781	Human UDP-glucuronosyltransferase UGT2A2: cDNA construction, expression, and functional characterization in comparison with UGT2A1 and UGT2A3.

Q92793	CBP_HUMAN	CREB-binding protein	18316612	Molecular basis of nuclear factor-kappaB activation by astrocyte elevated gene-1.

Q8K3R3	PLCD4_MOUSE	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-4	11340203	Requirement of phospholipase Cdelta4 for the zona pellucida-induced acrosome reaction.

P38302	NTC20_YEAST	Pre-mRNA-splicing factor NTC20	11018040	Identification and characterization of two novel components of the Prp19p-associated complex, Ntc30p and Ntc20p.

P18583	SON_HUMAN	Protein SON	10509013	A selection system for human apoptosis inhibitors using yeast.

Q9VS50	ECO_DROME	N-acetyltransferase eco	14653991	Two putative acetyltransferases, san and deco, are required for establishing sister chromatid cohesion in Drosophila.

P33078	IAA5_ARATH	Auxin-responsive protein IAA5	2102379	Structure and expression of two auxin-inducible genes from Arabidopsis.

P38111	ATR_YEAST	Serine/threonine-protein kinase MEC1	11095737	Protein kinase activity of Tel1p and Mec1p, two Saccharomyces cerevisiae proteins related to the human ATM protein kinase.

O88712	CTBP1_MOUSE	C-terminal-binding protein 1	14701752	Transcriptional and DNA binding activity of the Foxp1/2/4 family is modulated by heterotypic and homotypic protein interactions.

P49366	DHYS_HUMAN	Deoxyhypusine synthase	7673224	Cloning and expression of human deoxyhypusine synthase cDNA. Structure-function studies with the recombinant enzyme and mutant proteins.

Q9W4E2	NBEA_DROME	Neurobeachin	9334242	Molecular characterization of a novel A kinase anchor protein from Drosophila melanogaster.

O95490	LPHN2_HUMAN	Latrophilin-2	10030676	Isolation and characterisation of a human homologue of the latrophilin gene from a region of 1p31.1 implicated in breast cancer.

Q9H3D4	P63_HUMAN	Tumor protein 63	9662378	Cloning and functional analysis of human p51, which structurally and functionally resembles p53.

Q9P6L5	SLA2_SCHPO	Endocytosis protein end4	15827087	End4/Sla2 is involved in establishment of a new growth zone in Schizosaccharomyces pombe.

Q9SAC6	GWD1_ARATH	Alpha-glucan water dikinase 1, chloroplastic	11487701	The Arabidopsis sex1 mutant is defective in the R1 protein, a general regulator of starch degradation in plants, and not in the chloroplast hexose transporter.

P46783	RS10_HUMAN	40S ribosomal protein S10	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

P60228	EIF3E_HUMAN	Eukaryotic translation initiation factor 3 subunit E	17324924	Mammalian tumor suppressor Int6 specifically targets hypoxia inducible factor 2 alpha for degradation by hypoxia- and pVHL- independent regulation.

P25573	MGR1_YEAST	Mitochondrial inner membrane i-AAA protease supercomplex subunit MGR1	14562095	Global analysis of protein localization in budding yeast.

P38314	SDS24_YEAST	Protein SDS24	14562095	Global analysis of protein localization in budding yeast.

Q15029	U5S1_HUMAN	116 kDa U5 small nuclear ribonucleoprotein component	9774689	The human U5-220kD protein (hPrp8) forms a stable RNA-free complex with several U5-specific proteins, including an RNA unwindase, a homologue of ribosomal elongation factor EF-2, and a novel WD-40 protein.

O22229	TRXB3_ARATH	NADPH-dependent thioredoxin reductase 3	16884685	The C-type Arabidopsis thioredoxin reductase ANTR-C acts as an electron donor to 2-Cys peroxiredoxins in chloroplasts.

Q9EQV9	CBPB2_RAT	Carboxypeptidase B2	11021404	Molecular cloning and partial characterization of rat procarboxypeptidase R and carboxypeptidase N.

O60112	YG63_SCHPO	Uncharacterized Rab geranylgeranyltransferase C15C4.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q1HQF8	KTAP2_AEDAE	Protein KRTCAP2 homolog	17204158	An annotated catalogue of salivary gland transcripts in the adult female mosquito, Aedes aegypti.

P36162	DAD2_YEAST	DASH complex subunit DAD2	15640796	The yeast DASH complex forms closed rings on microtubules.

P49747	COMP_HUMAN	Cartilage oligomeric matrix protein	15075323	Interactions between the cartilage oligomeric matrix protein and matrilins. Implications for matrix assembly and the pathogenesis of chondrodysplasias.

O15231	ZN185_HUMAN	Zinc finger protein 185	9268636	Genomic structure of a novel LIM domain gene (ZNF185) in Xq28 and comparisons with the orthologous murine transcript.

Q9UBP6	TRMB_HUMAN	tRNA (guanine-N(7)-)-methyltransferase	12403464	Two proteins that form a complex are required for 7-methylguanosine modification of yeast tRNA.

Q9PVV4	PCM1_XENLA	Pericentriolar material 1 protein	10579718	Centriolar satellites: molecular characterization, ATP-dependent movement toward centrioles and possible involvement in ciliogenesis.

Q03001	BPA1_HUMAN	Bullous pemphigoid antigen 1	19632184	An EB1-binding motif acts as a microtubule tip localization signal.

P05166	PCCB_HUMAN	Propionyl-CoA carboxylase beta chain, mitochondrial	8188292	Correction of the metabolic defect in propionic acidemia fibroblasts by microinjection of a full-length cDNA or RNA transcript encoding the propionyl-CoA carboxylase beta subunit.

Q9VR94	OB19A_DROME	General odorant-binding protein 19a	11729153	A large family of divergent Drosophila odorant-binding proteins expressed in gustatory and olfactory sensilla.

Q91572	CPE1A_XENLA	Cytoplasmic polyadenylation element-binding protein 1-A	17942399	CPEB interacts with an ovary-specific eIF4E and 4E-T in early Xenopus oocytes.

O02626	MADD_CAEEL	MAP kinase-activating death domain protein	9136770	aex-3 encodes a novel regulator of presynaptic activity in C. elegans.

Q62141	SIN3B_MOUSE	Paired amphipathic helix protein Sin3b	10620510	The winged-helix/forkhead protein myocyte nuclear factor beta (MNF- beta) forms a co-repressor complex with mammalian Sin3B.

Q9NQB0	TF7L2_HUMAN	Transcription factor 7-like 2	9727977	Identification of c-MYC as a target of the APC pathway.

O42881	APTH1_SCHPO	Acyl-protein thioesterase 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q08116	RGS1_HUMAN	Regulator of G-protein signaling 1	8241276	A B cell specific immediate early human gene is located on chromosome band 1q31 and encodes an alpha helical basic phosphoprotein.

Q9UPY3	DICER_HUMAN	Endoribonuclease Dicer	15973356	TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing.

Q8IVG9	HUNIN_HUMAN	Humanin	11371646	A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Abeta.

Q02642	NACB1_YEAST	Nascent polypeptide-associated complex subunit beta-1	16926149	The yeast Ccr4-Not complex controls ubiquitination of the nascent- associated polypeptide (NAC-EGD) complex.

P0A6P7	ENGB_ECOLI	Probable GTP-binding protein engB	10572302	A new essential gene of the 'minimal genome' affecting cell division.

P25516	ACON1_ECOLI	Aconitate hydratase 1	1838390	The aconitase of Escherichia coli: purification of the enzyme and molecular cloning and map location of the gene (acn).

O42906	NPA3_SCHPO	GTPase npa3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P17152	TMM11_HUMAN	Transmembrane protein 11	2110658	Nucleotide sequence of a cDNA encoding a protein with primary structural similarity to G-protein coupled receptors.

Q9Y2D1	ATF5_HUMAN	Cyclic AMP-dependent transcription factor ATF-5	10373550	Human Cdc34 and Rad6B ubiquitin-conjugating enzymes target repressors of cyclic AMP-induced transcription for proteolysis.

Q2PW47	MED24_DANRE	Mediator of RNA polymerase II transcription subunit 24	16582438	Differential roles of transcriptional mediator complex subunits Crsp34/Med27, Crsp150/Med14 and Trap100/Med24 during zebrafish retinal development.

O00308	WWP2_HUMAN	NEDD4-like E3 ubiquitin-protein ligase WWP2	9647693	Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins.

P53615	CAN_YEAST	Carbonic anhydrase	14562095	Global analysis of protein localization in budding yeast.

O80860	FTSH2_ARATH	ATP-dependent zinc metalloprotease FTSH 2, chloroplastic	10849347	Mutations in the Arabidopsis VAR2 locus cause leaf variegation due to the loss of a chloroplast FtsH protease.

P42685	FRK_HUMAN	Tyrosine-protein kinase FRK	7510261	Cloning of FRK, a novel human intracellular SRC-like tyrosine kinase- encoding gene.

Q09868	CIP2_SCHPO	RNA-binding post-transcriptional regulator cip2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P08590	MYL3_HUMAN	Myosin light chain 3	2789520	Human ventricular/slow twitch myosin alkali light chain gene characterization, sequence, and chromosomal location.

Q12271	INP53_YEAST	Inositol-1,4,5-trisphosphate 5-phosphatase 3	10224048	SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatases.

P09972	ALDOC_HUMAN	Fructose-bisphosphate aldolase C	3105602	The complete amino acid sequence of the human aldolase C isozyme derived from genomic clones.

Q924V1	NOX4_RAT	NADPH oxidase 4	11348997	Novel gp91(phox) homologues in vascular smooth muscle cells: nox1 mediates angiotensin II-induced superoxide formation and redox- sensitive signaling pathways.

O82782	HIS4_ARATH	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, chloroplastic	9747713	Molecular cloning and characterization of the gene encoding N'-[(5'- phosphoribosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide (BBM II) isomerase from Arabidopsis thaliana.

P32339	HMX1_YEAST	Heme-binding protein HMX1	11112771	Mitochondrial control of iron homeostasis. A genome wide analysis of gene expression in a yeast frataxin-deficient strain.

P0AB77	KBL_ECOLI	2-amino-3-ketobutyrate coenzyme A ligase	11318637	Three-dimensional structure of 2-amino-3-ketobutyrate CoA ligase from Escherichia coli complexed with a PLP-substrate intermediate: inferred reaction mechanism.

P49893	WN11B_XENLA	Protein Wnt-11b	11159911	Wnt antagonism initiates cardiogenesis in Xenopus laevis.

P29101	SYT2_RAT	Synaptotagmin-2	1856191	Synaptotagmin II. A novel differentially distributed form of synaptotagmin.

Q04458	HFD1_YEAST	Putative fatty aldehyde dehydrogenase HFD1	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q71M36	CSPG5_MOUSE	Chondroitin sulfate proteoglycan 5	15848802	Impaired synapse function during postnatal development in the absence of CALEB, an EGF-like protein processed by neuronal activity.

P0C079	RELB_ECOLI	Antitoxin RelB	9767574	The Escherichia coli relBE genes belong to a new toxin-antitoxin gene family.

Q12317	MSB4_YEAST	GTPase-activating protein MSB4	10679030	Identification of novel, evolutionarily conserved Cdc42p-interacting proteins and of redundant pathways linking Cdc24p and Cdc42p to actin polarization in yeast.

Q27889	PP2B2_DROME	Serine/threonine-protein phosphatase 2B catalytic subunit 2	8313960	Identification of a cDNA encoding a Drosophila calcium/calmodulin regulated protein phosphatase, which has its most abundant expression in the early embryo.

O36028	ATCZ_SCHPO	Putative phospholipid-transporting ATPase C4F10.16c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9XXU9	VATC_CAEEL	V-type proton ATPase subunit C	10846178	Requirement of V-ATPase for ovulation and embryogenesis in Caenorhabditis elegans.

Q9ULV1	FZD4_HUMAN	Frizzled-4	15035989	Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair.

Q9P785	YNY5_SCHPO	LisH domain-containing protein C1711.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q86VZ1	P2RY8_HUMAN	P2Y purinoceptor 8	11004484	Expression of purinergic receptors (ionotropic P2X1-7 and metabotropic P2Y1-11) during myeloid differentiation of HL60 cells.

Q801F7	WN10B_DANRE	Protein Wnt-10b	12591239	Wnt1 and wnt10b function redundantly at the zebrafish midbrain- hindbrain boundary.

Q00P32	HES2_XENLA	Transcription factor HES-2	17008450	Characterization and function of the bHLH-O protein XHes2: insight into the mechanisms controlling retinal cell fate decision.

O76024	WFS1_HUMAN	Wolframin	9771706	A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram Syndrome).

P41891	GAR2_SCHPO	Protein gar2	7596817	gar2 is a nucleolar protein from Schizosaccharomyces pombe required for 18S rRNA and 40S ribosomal subunit accumulation.

Q7M3M8	CAS_DROME	Transcription factor castor	11335107	The Drosophila castor gene is involved in postembryonic brain development.

P27653	C1TC_RAT	C-1-tetrahydrofolate synthase, cytoplasmic	2186031	Rat C1-tetrahydrofolate synthase. cDNA isolation, tissue-specific levels of the mRNA, and expression of the protein in yeast.

Q15165	PON2_HUMAN	Serum paraoxonase/arylesterase 2	8661009	The human serum paraoxonase/arylesterase gene (PON1) is one member of a multigene family.

P36613	CGM2_SCHPO	Cyclin mcs2	15555586	Mcs2 and a novel CAK subunit Pmh1 associate with Skp1 in fission yeast.

Q9S834	CLPP5_ARATH	ATP-dependent Clp protease proteolytic subunit 5, chloroplastic	11278690	Identification of a 350-kDa ClpP protease complex with 10 different Clp isoforms in chloroplasts of Arabidopsis thaliana.

P51610	HCFC1_HUMAN	Host cell factor 1	8392914	The VP16 accessory protein HCF is a family of polypeptides processed from a large precursor protein.

P23686	METK1_ARATH	S-adenosylmethionine synthase 1	16365035	Differential inhibition of Arabidopsis methionine adenosyltransferases by protein S-nitrosylation.

Q9Y446	PKP3_HUMAN	Plakophilin-3	10374265	Plakophilin 3 -- a novel cell-type-specific desmosomal plaque protein.

Q05860	FMN1_MOUSE	Formin-1	14647292	Mammalian formin-1 participates in adherens junctions and polymerization of linear actin cables.

O75503	CLN5_HUMAN	Ceroid-lipofuscinosis neuronal protein 5	11971870	Lysosomal localization of the neuronal ceroid lipofuscinosis CLN5 protein.

O95992	CH25H_HUMAN	Cholesterol 25-hydroxylase	9852097	cDNA cloning of mouse and human cholesterol 25-hydroxylases, polytopic membrane proteins that synthesize a potent oxysterol regulator of lipid metabolism.

P25693	PCL2_YEAST	PHO85 cyclin-2	7973731	The PCL2 (ORFD)-PHO85 cyclin-dependent kinase complex: a cell cycle regulator in yeast.

Q14596	NBR1_HUMAN	Next to BRCA1 gene 1 protein	19427866	Interactions with LC3 and polyubiquitin chains link nbr1 to autophagic protein turnover.

Q12080	NOP53_YEAST	Ribosome biogenesis protein NOP53	15686447	Nop53p is a novel nucleolar 60S ribosomal subunit biogenesis protein.

Q1L721	RN138_XENLA	E3 ubiquitin-protein ligase RNF138	16714285	NARF, an nemo-like kinase (NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF).

Q15382	RHEB_HUMAN	GTP-binding protein Rheb	8543055	A novel approach for expression cloning of small GTPases: identification, tissue distribution and chromosome mapping of the human homolog of rheb.

Q15554	TERF2_HUMAN	Telomeric repeat-binding factor 2	9326950	Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2.

P40552	TIR3_YEAST	Cell wall protein TIR3	10383953	Amino acid residues in the omega-minus region participate in cellular localization of yeast glycosylphosphatidylinositol-attached proteins.

Q9UKM9	RALY_HUMAN	RNA-binding protein Raly	9376072	The p542 gene encodes an autoantigen that cross-reacts with EBNA-1 of the Epstein Barr virus and which may be a heterogeneous nuclear ribonucleoprotein.

P21333	FLNA_HUMAN	Filamin-A	12393796	Filamin A and filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact.

P17791	VIRB1_AGRT5	Protein virB1	2233252	Characterization of the virB operon of an Agrobacterium tumefaciens Ti plasmid: nucleotide sequence and protein analysis.

Q16666	IF16_HUMAN	Gamma-interferon-inducible protein 16	9642285	The human interferon-inducible protein, IFI 16, is a repressor of transcription.

O76064	RNF8_HUMAN	E3 ubiquitin-protein ligase RNF8	18948756	PCNA is ubiquitinated by RNF8.

Q9HAZ2	PRD16_HUMAN	PR domain zinc finger protein 16	12816872	A novel EVI1 gene family, MEL1, lacking a PR domain (MEL1S) is expressed mainly in t(1;3)(p36;q21)-positive AML and blocks G-CSF- induced myeloid differentiation.

Q8L940	PDX13_ARATH	Pyridoxal biosynthesis protein PDX1.3	16236150	Pyridoxine is required for post-embryonic root development and tolerance to osmotic and oxidative stresses.

O59793	BIS1_SCHPO	Stress response protein bis1	11751918	The fission yeast ES2 homologue, Bis1, interacts with the Ish1 stress-responsive nuclear envelope protein.

P14724	CDC26_YEAST	Anaphase-promoting complex subunit CDC26	8895471	Identification of subunits of the anaphase-promoting complex of Saccharomyces cerevisiae.

Q99JG7	TNIP2_MOUSE	TNFAIP3-interacting protein 2	11390377	Identification of a novel A20-binding inhibitor of nuclear factor- kappaB activation termed ABIN-2.

P14083	TKR_DROME	Protein TKR	16631157	Single-cell mapping of neural and glial gene expression in the developing Drosophila CNS midline cells.

O49722	PUP6_ARATH	Probable purine permease 6	10662864	A new family of high-affinity transporters for adenine, cytosine, and purine derivatives in Arabidopsis.

Q9AR19	GCN5_ARATH	Histone acetyltransferase GCN5	11266554	Transcriptional adaptor and histone acetyltransferase proteins in Arabidopsis and their interactions with CBF1, a transcriptional activator involved in cold-regulated gene expression.

O42977	YGZ8_SCHPO	Uncharacterized protein C20F10.08c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q64537	CPNS1_RAT	Calpain small subunit 1	7982961	Active recombinant rat calpain II. Bacterially produced large and small subunits associate both in vivo and in vitro.

O94510	AGN2_SCHPO	Glucan endo-1,3-alpha-glucosidase agn2	15194814	Role of the alpha-glucanase Agn1p in fission-yeast cell separation.

P38862	ATG7_YEAST	Ubiquitin-like modifier-activating enzyme ATG7	15277523	In vivo and in vitro reconstitution of atg8 conjugation essential for autophagy.

P28648	CD63_RAT	CD63 antigen	1634775	The rat mast cell antigen AD1 (homologue to human CD63 or melanoma antigen ME491) is expressed in other cells in culture.

P40159	YNU8_YEAST	Uncharacterized protein YNL208W	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P0AEA5	CYOE_ECOLI	Protoheme IX farnesyltransferase	8253713	In vitro heme O synthesis by the cyoE gene product from Escherichia coli.

Q99463	NPY6R_HUMAN	Putative neuropeptide Y receptor type 6	9013614	Molecular genetic analysis of a human neuropeptide Y receptor. The human homolog of the murine 'Y5' receptor may be a pseudogene.

O88566	AXN2_MOUSE	Axin-2	9554852	Functional interaction of an axin homolog, conductin, with beta- catenin, APC, and GSK3beta.

Q9UNE7	CHIP_HUMAN	E3 ubiquitin-protein ligase CHIP	15466472	Ubiquitylation of neuronal nitric-oxide synthase by CHIP, a chaperone-dependent E3 ligase.

P58012	FOXL2_HUMAN	Forkhead box protein L2	12161610	FOXL2 mutation screening in a large panel of POF patients and XX males.

P07948	LYN_HUMAN	Tyrosine-protein kinase Lyn	3561390	The yes-related cellular gene lyn encodes a possible tyrosine kinase similar to p56lck.

O59748	CTK2_SCHPO	CTD kinase subunit beta	17502918	A cyclin-dependent kinase that promotes cytokinesis through modulating phosphorylation of the carboxy terminal domain of the RNA Pol II Rpb1p sub-unit.

Q6QI06	RICTR_MOUSE	Rapamycin-insensitive companion of mTOR	15467718	Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive.

P32332	OAC1_YEAST	Mitochondrial oxaloacetate transport protein	10428783	Identification of the yeast mitochondrial transporter for oxaloacetate and sulfate.

Q9JI78	NGLY1_MOUSE	Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	15358861	A complex between peptide:N-glycanase and two proteasome-linked proteins suggests a mechanism for the degradation of misfolded glycoproteins.

P25372	TRX3_YEAST	Thioredoxin-3, mitochondrial	10037727	Identification and functional characterization of a novel mitochondrial thioredoxin system in Saccharomyces cerevisiae.

Q02792	XRN2_YEAST	5'-3' exoribonuclease 2	11142370	The final step in the formation of 25S rRNA in Saccharomyces cerevisiae is performed by 5'->3' exonucleases.

Q9VPT1	GR21A_DROME	Gustatory and odorant receptor 21a	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

A7YE96	TT30A_DANRE	Tetratricopeptide repeat protein 30A	17761526	The zebrafish fleer gene encodes an essential regulator of cilia tubulin polyglutamylation.

Q8IMX7	MIRO_DROME	Mitochondrial Rho GTPase	14605208	A protein interaction map of Drosophila melanogaster.

Q9UMX1	SUFU_HUMAN	Suppressor of fused homolog	10806483	Gli regulation by the opposing activities of fused and suppressor of fused.

Q6IFX1	K1C24_RAT	Keratin, type I cytoskeletal 24	15085952	Comprehensive analysis of keratin gene clusters in humans and rodents.

Q04439	MYO5_YEAST	Myosin-5	8614799	Role of type I myosins in receptor-mediated endocytosis in yeast.

P80645	SSUD_ECOLI	Alkanesulfonate monooxygenase	10506196	The Escherichia coli ssuEADCB gene cluster is required for the utilization of sulfur from aliphatic sulfonates and is regulated by the transcriptional activator Cbl.

Q12692	H2AZ_YEAST	Histone H2A.Z	11090616	A histone variant, Htz1p, and a Sir1p-like protein, Esc2p, mediate silencing at HMR.

P85122	SLAP1_BACHK	S-layer protein 1	16404726	Mass spectrometric sequencing of endotoxin proteins of Bacillus thuringiensis ssp. konkukian extracted from polyacrylamide gels.

P36210	RK121_ARATH	50S ribosomal protein L12-1, chloroplastic	8125949	Multicopy GTPase center protein L12 of Arabidopsis chloroplast ribosome is encoded by a clustered nuclear gene family with the expressed members closely linked to tRNA(Pro) genes.

Q9GZV9	FGF23_HUMAN	Fibroblast growth factor 23	16638743	Polypeptide GalNAc-transferase T3 and familial tumoral calcinosis. Secretion of fibroblast growth factor 23 requires O-glycosylation.

O55187	CBX4_MOUSE	E3 SUMO-protein ligase CBX4	9367786	MPc2, a new murine homolog of the Drosophila polycomb protein is a member of the mouse polycomb transcriptional repressor complex.

O60060	CARA_SCHPO	Carbamoyl-phosphate synthase arginine-specific small chain	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9SFB7	QRT2_ARATH	Polygalacturonase QRT2	8197459	Tetrad analysis possible in Arabidopsis with mutation of the QUARTET (QRT) genes.

Q9UBP0	SPAST_HUMAN	Spastin	16026783	Spastin subcellular localization is regulated through usage of different translation start sites and active export from the nucleus.

Q92834	RPGR_HUMAN	X-linked retinitis pigmentosa GTPase regulator	12140192	Species-specific subcellular localization of RPGR and RPGRIP isoforms: implications for the phenotypic variability of congenital retinopathies among species.

Q9NQW7	XPP1_HUMAN	Xaa-Pro aminopeptidase 1	18515364	Structure of human cytosolic X-prolyl aminopeptidase: a double Mn(II)-dependent dimeric enzyme with a novel three-domain subunit.

Q9EQX0	GHRL_MOUSE	Appetite-regulating hormone	10930375	Identification and characterization of a novel gastric peptide hormone: the motilin-related peptide.

Q86YM7	HOME1_HUMAN	Homer protein homolog 1	9808458	Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins.

Q13564	ULA1_HUMAN	NEDD8-activating enzyme E1 regulatory subunit	10207026	Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway.

Q99814	EPAS1_HUMAN	Endothelial PAS domain-containing protein 1	9000051	Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells.

Q8CI59	STEA3_MOUSE	Metalloreductase STEAP3	16227996	Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells.

O04719	P2C77_ARATH	Protein phosphatase 2C 77	19407143	Regulators of PP2C phosphatase activity function as abscisic acid sensors.

Q60611	SATB1_MOUSE	DNA-binding protein SATB1	8114718	A novel DNA-binding motif in the nuclear matrix attachment DNA- binding protein SATB1.

Q9FVC1	SVP_ARATH	MADS-box protein SVP	18694458	AGAMOUS-LIKE24 and SHORT VEGETATIVE PHASE determine floral meristem identity in Arabidopsis.

P53095	DSD1_YEAST	D-serine dehydratase	17869212	Enzymatic assay of D-serine using D-serine dehydratase from Saccharomyces cerevisiae.

O60762	DPM1_HUMAN	Dolichol-phosphate mannosyltransferase	9535917	A homologue of Saccharomyces cerevisiae Dpm1p is not sufficient for synthesis of dolichol-phosphate-mannose in mammalian cells.

Q15620	OR8B8_HUMAN	Olfactory receptor 8B8	9119360	Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species.

Q38898	AKT2_ARATH	Potassium channel AKT2/3	12034902	Physical and functional interaction of the Arabidopsis K(+) channel AKT2 and phosphatase AtPP2CA.

O74941	PEX1_SCHPO	Peroxisomal ATPase pex1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9P2W9	STX18_HUMAN	Syntaxin-18	15029241	Implication of ZW10 in membrane trafficking between the endoplasmic reticulum and Golgi.

Q64436	ATP4A_MOUSE	Potassium-transporting ATPase alpha chain 1	7762614	Primary structure and functional expression of the mouse and frog alpha-subunit of the gastric H(+)-K(+)-ATPase.

P04041	GPX1_RAT	Glutathione peroxidase 1	1451786	Cloning and characterization of the rat glutathione peroxidase gene.

Q9WVR1	INP5E_RAT	72 kDa inositol polyphosphate 5-phosphatase	10405344	Pharbin, a novel inositol polyphosphate 5-phosphatase, induces dendritic appearances in fibroblasts.

P01584	IL1B_HUMAN	Interleukin-1 beta	3493774	cDNA cloning of IL-1 alpha and IL-1 beta from mRNA of U937 cell line.

Q99P77	NOG1_RAT	Nucleolar GTP-binding protein 1	11316846	Identification of a novel nuclear guanosine triphosphate-binding protein differentially expressed in renal disease.

O88470	FOXL2_MOUSE	Forkhead box protein L2	19797124	Foxl2, a forkhead transcription factor, modulates nonclassical activity of the estrogen receptor-alpha.

Q10426	RIK1_SCHPO	Chromatin modification-related protein rik1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q92966	SNPC3_HUMAN	snRNA-activating protein complex subunit 3	9003788	Cloning and characterization of SNAP50, a subunit of the snRNA- activating protein complex SNAPc.

P15938	PRP16_YEAST	Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16	1825134	PRP16 is an RNA-dependent ATPase that interacts transiently with the spliceosome.

P48563	MON2_YEAST	Protein MON2	12134085	Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae.

P27361	MK03_HUMAN	Mitogen-activated protein kinase 3	7687743	Molecular cloning, expression, and characterization of the human mitogen-activated protein kinase p44erk1.

O43927	CXL13_HUMAN	C-X-C motif chemokine 13	9486651	A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1.

O95843	GUC1C_HUMAN	Guanylyl cyclase-activating protein 3	10037746	Molecular characterization of a third member of the guanylyl cyclase- activating protein subfamily.

P23469	PTPRE_HUMAN	Receptor-type tyrosine-protein phosphatase epsilon	19167335	Large-scale structural analysis of the classical human protein tyrosine phosphatome.

P49956	CTF18_YEAST	Chromosome transmission fidelity protein 18	11486023	Chl12 (Ctf18) forms a novel replication factor C-related complex and functions redundantly with Rad24 in the DNA replication checkpoint pathway.

Q9USP2	YND1_SCHPO	Golgi apyrase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P13533	MYH6_HUMAN	Myosin-6	15735645	Mutation in myosin heavy chain 6 causes atrial septal defect.

Q9HGM4	SCS3_SCHPO	FIT family protein scs3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P32929	CGL_HUMAN	Cystathionine gamma-lyase	19019829	Structural basis for the inhibition mechanism of human cystathionine gamma-lyase, an enzyme responsible for the production of H(2)S.

Q03691	ROT1_YEAST	Protein ROT1	17606994	Rot1 plays an antagonistic role to Clb2 in actin cytoskeleton dynamics throughout the cell cycle.

Q7Z3C6	ATG9A_HUMAN	Autophagy-related protein 9A	15755735	Endothelial nitric-oxide synthase antisense (NOS3AS) gene encodes an autophagy-related protein (APG9-like2) highly expressed in trophoblast.

P38805	RPF1_YEAST	Ribosome production factor 1	11864606	The sigma(70)-like motif: a eukaryotic RNA binding domain unique to a superfamily of proteins required for ribosome biogenesis.

Q9NVV4	PAPD1_HUMAN	Poly(A) RNA polymerase, mitochondrial	18172165	Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'.

P35184	SQT1_YEAST	Ribosome assembly protein SQT1	9271392	SQT1, which encodes an essential WD domain protein of Saccharomyces cerevisiae, suppresses dominant-negative mutations of the ribosomal protein gene QSR1.

P23634	AT2B4_HUMAN	Plasma membrane calcium-transporting ATPase 4	2137451	Peptide sequence analysis and molecular cloning reveal two calcium pump isoforms in the human erythrocyte membrane.

P29310	1433Z_DROME	14-3-3 protein zeta	10230800	A dynamically regulated 14-3-3, Slob, and Slowpoke potassium channel complex in Drosophila presynaptic nerve terminals.

Q09732	DCC1_SCHPO	Sister chromatid cohesion protein dcc1	15226378	Sister-chromatid cohesion mediated by the alternative RF- CCtf18/Dcc1/Ctf8, the helicase Chl1 and the polymerase-alpha- associated protein Ctf4 is essential for chromatid disjunction during meiosis II.

Q9N4V0	FLP18_CAEEL	FMRFamide-like neuropeptide 18	11527423	Isolation and preliminary biological assessment of AADGAPLIRFamide and SVPGVLRFamide from Caenorhabditis elegans.

P0ABV6	TOLR_ECOLI	Protein tolR	8331075	Membrane topologies of the TolQ and TolR proteins of Escherichia coli: inactivation of TolQ by a missense mutation in the proposed first transmembrane segment.

P78972	SLP1_SCHPO	WD repeat-containing protein slp1	11909965	Fission yeast Mad3p is required for Mad2p to inhibit the anaphase- promoting complex and localizes to kinetochores in a Bub1p-, Bub3p-, and Mph1p-dependent manner.

Q96S59	RANB9_HUMAN	Ran-binding protein 9	9817760	When overexpressed, a novel centrosomal protein, RanBPM, causes ectopic microtubule nucleation similar to gamma-tubulin.

Q9SYM1	Y1861_ARATH	Uncharacterized mscS family protein At1g78610	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q08926	UIP4_YEAST	ULP1-interacting protein 4	11056382	Yeast Ulp1, an Smt3-specific protease, associates with nucleoporins.

Q05881	YL287_YEAST	Uncharacterized protein YLR287C	14562095	Global analysis of protein localization in budding yeast.

Q9EXP2	SUFS_DICD3	Cysteine desulfurase	12876288	Biogenesis of Fe-S cluster by the bacterial Suf system: SufS and SufE form a new type of cysteine desulfurase.

P10767	FGF6_HUMAN	Fibroblast growth factor 6	2649847	Characterization of the HST-related FGF.6 gene, a new member of the fibroblast growth factor gene family.

P01763	HV302_HUMAN	Ig heavy chain V-III region WEA	6410398	Amino acid sequence of the Fv region of a human monoclonal IgM (protein WEA) with antibody activity against 3,4-pyruvylated galactose in Klebsiella polysaccharides K30 and K33.

Q924A0	TF7L2_MOUSE	Transcription factor 7-like 2	9488439	Two members of the Tcf family implicated in Wnt/b-catenin signaling during embryogenesis in the mouse.

O74991	POF3_SCHPO	F-box/TPR repeat protein pof3	11809834	Fission yeast F-box protein Pof3 is required for genome integrity and telomere function.

P84278	PA2A_RANPA	Palustrin-2a	11087945	Multiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris.

P39516	RS14B_YEAST	40S ribosomal protein S14-B	15590835	The small-subunit processome is a ribosome assembly intermediate.

Q09723	TR112_SCHPO	Multifunctional methyltransferase subunit trm112	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q00577	PURA_HUMAN	Transcriptional activator protein Pur-alpha	1448097	Sequence of cDNA comprising the human pur gene and sequence-specific single-stranded-DNA-binding properties of the encoded protein.

P35691	TCTP_YEAST	Translationally-controlled tumor protein homolog	14562095	Global analysis of protein localization in budding yeast.

Q75QN2	INT8_HUMAN	Integrator complex subunit 8	16239144	Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.

P00634	PPB_ECOLI	Alkaline phosphatase	3910843	Refined structure of alkaline phosphatase from Escherichia coli at 2.8-A resolution.

Q94AG2	SERK1_ARATH	Somatic embryogenesis receptor kinase 1	11706164	The Arabidopsis SOMATIC EMBRYOGENESIS RECEPTOR KINASE 1 gene is expressed in developing ovules and embryos and enhances embryogenic competence in culture.

P60766	CDC42_MOUSE	Cell division control protein 42 homolog	15710388	Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes.

Q9LX29	ACR4_ARATH	Serine/threonine-protein kinase-like protein ACR4	18948541	Receptor-like kinase ACR4 restricts formative cell divisions in the Arabidopsis root.

Q54I18	SMEK_DICDI	Suppressor of Mek1	17353263	MEK1 and protein phosphatase 4 coordinate Dictyostelium development and chemotaxis.

Q9C5Y2	KAO2_ARATH	Ent-kaurenoic acid oxidase 2	11172076	The CYP88A cytochrome P450, ent-kaurenoic acid oxidase, catalyzes three steps of the gibberellin biosynthesis pathway.

P35398	RORA_HUMAN	Nuclear receptor ROR-alpha	7926749	Isoform-specific amino-terminal domains dictate DNA-binding properties of ROR alpha, a novel family of orphan hormone nuclear receptors.

Q9UGI0	ZRAN1_HUMAN	Ubiquitin thioesterase ZRANB1	18281465	Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains.

O04425	FCA_ARATH	Flowering time control protein FCA	9182761	FCA, a gene controlling flowering time in Arabidopsis, encodes a protein containing RNA-binding domains.

P80020	FABP6_RAT	Gastrotropin	8422242	Cloning of a cDNA encoding rat intestinal 15 kDa protein and its tissue distribution.

P32609	PEP7_YEAST	Vacuolar segregation protein PEP7	9168472	Pep7p provides a novel protein that functions in vesicle-mediated transport between the yeast Golgi and endosome.

P33205	FXA4A_XENLA	Forkhead box protein A4-A	1358174	Activin A induced expression of a fork head related gene in posterior chordamesoderm (notochord) of Xenopus laevis embryos.

Q02759	LX12L_RAT	Arachidonate 12-lipoxygenase, leukocyte-type	8444196	Molecular cloning of a 12-lipoxygenase cDNA from rat brain.

P73070	PSBJ_SYNY3	Photosystem II reaction center protein J	12069591	Proteomic analysis of a highly active photosystem II preparation from the cyanobacterium Synechocystis sp. PCC 6803 reveals the presence of novel polypeptides.

Q9ZZX1	SCE4_YEAST	Intron-encoded DNA endonuclease aI5 alpha	1314207	The yeast mitochondrial intron aI5 alpha: associated endonuclease activity and in vivo mobility.

P19357	GTR4_RAT	Solute carrier family 2, facilitated glucose transporter member 4	16396496	Insulin-dependent interactions of proteins with GLUT4 revealed through stable isotope labeling by amino acids in cell culture (SILAC).

Q5HZ36	GAT21_ARATH	GATA transcription factor 21	19962994	PAH-domain-specific interactions of the Arabidopsis transcription coregulator SIN3-LIKE1 (SNL1) with telomere-binding protein 1 and ALWAYS EARLY2 Myb-DNA binding factors.

Q8VZB2	PAS2_ARATH	3-hydroxyacyl-CoA dehydratase PASTICCINO 2	16698944	Arabidopsis PASTICCINO2 is an antiphosphatase involved in regulation of cyclin-dependent kinase A.

P38210	LDB7_YEAST	Chromatin structure-remodeling complex protein RSC14	14587103	Screening for new yeast mutants affected in mannosylphosphorylation of cell wall mannoproteins.

O88696	CLPP_MOUSE	Putative ATP-dependent Clp protease proteolytic subunit, mitochondrial	10754102	Characterization of mouse Clpp protease cDNA, gene, and protein.

Q9UJX3	APC7_HUMAN	Anaphase-promoting complex subunit 7	18485873	Mechanism of ubiquitin-chain formation by the human anaphase- promoting complex.

Q05778	POC1_YEAST	Proteasome chaperone 1	17431397	Beta-subunit appendages promote 20S proteasome assembly by overcoming an Ump1-dependent checkpoint.

P19812	UBR1_YEAST	E3 ubiquitin-protein ligase UBR1	10581257	The E2-E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain.

P20585	MSH3_HUMAN	DNA mismatch repair protein Msh3	8942985	hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6.

Q8CFC1	MINA_RAT	Myc-induced nuclear antigen	12091391	A novel myc target gene, mina53, that is involved in cell proliferation.

P35251	RFC1_HUMAN	Replication factor C subunit 1	8248204	cDNAs encoding the large subunit of human replication factor C.

Q15836	VAMP3_HUMAN	Vesicle-associated membrane protein 3	9885218	Identification of a cellubrevin/vesicle associated membrane protein 3 homologue in human platelets.

Q55E58	PATS1_DICDI	Probable serine/threonine-protein kinase pats1	12529423	The identification of pats1, a novel gene locus required for cytokinesis in Dictyostelium discoideum.

Q9USR1	TXL1_SCHPO	Thioredoxin-like protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P78759	2AD2_SCHPO	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta 2 isoform	10757751	Isolation and characterization of par1(+) and par2(+): two Schizosaccharomyces pombe genes encoding B' subunits of protein phosphatase 2A.

O75874	IDHC_HUMAN	Isocitrate dehydrogenase [NADP] cytoplasmic	10521434	The human PICD gene encodes a cytoplasmic and peroxisomal NADP(+)- dependent isocitrate dehydrogenase.

Q8N138	ORML3_HUMAN	ORM1-like protein 3	12093374	ORMDL proteins are a conserved new family of endoplasmic reticulum membrane proteins.

P01241	SOMA_HUMAN	Somatotropin	8943276	Crystal structure of an antagonist mutant of human growth hormone, G120R, in complex with its receptor at 2.9-A resolution.

Q8RWU4	ATML1_ARATH	Homeobox-leucine zipper protein MERISTEM L1	16778018	Characterization of the class IV homeodomain-leucine zipper gene family in Arabidopsis.

Q5TAT6	CODA1_HUMAN	Collagen alpha-1(XIII) chain	11956183	The type XIII collagen ectodomain is a 150-nm rod and capable of binding to fibronectin, nidogen-2, perlecan, and heparin.

Q7TSE9	HAX1_RAT	HCLS1-associated protein X-1	15159385	Identification of HAX-1 as a protein that binds bile salt export protein and regulates its abundance in the apical membrane of Madin- Darby canine kidney cells.

Q91620	NOD2A_XENLA	Nodal homolog 2-A	16193491	Xnr2 and Xnr5 unprocessed proteins inhibit Wnt signaling upstream of dishevelled.

Q9U298	ACH8_CAEEL	Neuronal acetylcholine receptor subunit eat-2	8462849	The genetics of feeding in Caenorhabditis elegans.

P0A940	YAET_ECOLI	Outer membrane protein assembly factor yaeT	15851030	Identification of a multicomponent complex required for outer membrane biogenesis in Escherichia coli.

P20965	PABPA_XENLA	Polyadenylate-binding protein 1-A	15713657	Embryonic poly(A)-binding protein stimulates translation in germ cells.

Q8CFW1	ANO2_MOUSE	Anoctamin-2	19561302	ANO2 is the cilial calcium-activated chloride channel that may mediate olfactory amplification.

O15205	UBD_HUMAN	Ubiquitin D	14757770	NEDD8 ultimate buster-1L interacts with the ubiquitin-like protein FAT10 and accelerates its degradation.

P45844	ABCG1_HUMAN	ATP-binding cassette sub-family G member 1	11500512	Characterization of the human ABCG1 gene: liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the protein.

O94639	ZRT1_SCHPO	Zinc-regulated transporter 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O95402	MED26_HUMAN	Mediator of RNA polymerase II transcription subunit 26	9989412	The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1.

Q3E705	EFG1P_YEAST	rRNA-processing protein EFG1	16510898	Functional genomics of genes with small open reading frames (sORFs) in S. cerevisiae.

O00631	SARCO_HUMAN	Sarcolipin	9367679	Characterization of the gene encoding human sarcolipin (SLN), a proteolipid associated with SERCA1: absence of structural mutations in five patients with Brody disease.

P46963	CTK3_YEAST	CTD kinase subunit gamma	9110987	Modulation of RNA polymerase II elongation efficiency by C-terminal heptapeptide repeat domain kinase I.

O60315	ZEB2_HUMAN	Zinc finger E-box-binding homeobox 2	9853615	Selection system for genes encoding nuclear-targeted proteins.

Q07699	SCN1B_HUMAN	Sodium channel subunit beta-1	9697698	Febrile seizures and generalized epilepsy associated with a mutation in the Na(+)-channel beta-1 subunit gene SCN1B.

P13360	GLAS_DROME	Protein glass	7604032	Functional domain analysis of glass, a zinc-finger-containing transcription factor in Drosophila.

P11844	CRGA_HUMAN	Gamma-crystallin A	12507494	Homology models of human gamma-crystallins: structural study of the extensive charge network in gamma-crystallins.

Q9P3W5	TEL2_SCHPO	DNA replication checkpoint protein tel2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O74944	POLK_SCHPO	DNA polymerase kappa	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8IUD2	RB6I2_HUMAN	ELKS/Rab6-interacting/CAST family member 1	15218148	Activation of transcription factor NF-kappaB requires ELKS, an IkappaB kinase regulatory subunit.

O00463	TRAF5_HUMAN	TNF receptor-associated factor 5	9153189	ATAR, a novel tumor necrosis factor receptor family member, signals through TRAF2 and TRAF5.

Q9QZS7	NPHN_MOUSE	Nephrin	11733557	Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin.

Q8NFQ8	TOIP2_HUMAN	Torsin-1A-interacting protein 2	15767459	The AAA+ protein torsinA interacts with a conserved domain present in LAP1 and a novel ER protein.

P50942	INP52_YEAST	Inositol-1,4,5-trisphosphate 5-phosphatase 2	16406366	Sjl2p is specifically involved in early steps of endocytosis intimately linked to actin dynamics via the Ark1p/Prk1p kinases.

P50995	ANX11_HUMAN	Annexin A11	12805373	Dissecting the cellular functions of annexin XI using recombinant human annexin XI-specific autoantibodies cloned by phage display.

P38910	CH10_YEAST	10 kDa heat shock protein, mitochondrial	7903252	Cloning and disruption of the gene encoding yeast mitochondrial chaperonin 10, the homolog of E. coli groES.

Q06706	ELP1_YEAST	Elongator complex protein 1	12139626	Protein interactions within Saccharomyces cerevisiae Elongator, a complex essential for Kluyveromyces lactis zymocicity.

P34616	CADH3_CAEEL	Cadherin-3	9012534	cdh-3, a gene encoding a member of the cadherin superfamily, functions in epithelial cell morphogenesis in Caenorhabditis elegans.

Q7YXD4	P80_DICDI	Protein P80	11831389	Membrane sorting in the endocytic and phagocytic pathway of Dictyostelium discoideum.

O43318	M3K7_HUMAN	Mitogen-activated protein kinase kinase kinase 7	10094049	The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway.

O09102	GCM2_MOUSE	Chorion-specific transcription factor GCMb	9770492	Isolation and characterization of mammalian homologs of the Drosophila gene glial cells missing.

P54367	KC1A_DROME	Casein kinase I isoform alpha	8832407	The casein kinase 1 alpha gene of Drosophila melanogaster is developmentally regulated and the kinase activity of the protein induced by DNA damage.

Q8LBI1	RL51_ARATH	60S ribosomal protein L5-1	12711688	Identification and characterization of transcription factor IIIA and ribosomal protein L5 from Arabidopsis thaliana.

O48788	Y2267_ARATH	Probable inactive receptor kinase At2g26730	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q92729	PTPRU_HUMAN	Receptor-type tyrosine-protein phosphatase U	8700514	Characterization of PCP-2, a novel receptor protein tyrosine phosphatase of the MAM domain family.

Q9SLN5	AMP1A_ARATH	Methionine aminopeptidase 1A	11060042	Identification of eukaryotic peptide deformylases reveals universality of N-terminal protein processing mechanisms.

P49242	RS3A_RAT	40S ribosomal protein S3a	925037	Isolation of eukaryotic ribosomal proteins. Purification and characterization of the 40 S ribosomal subunit proteins Sa, Sc, S3a, S3b, S5', S9, S10, S11, S12, S14, S15, S15', S16, S17, S18, S19, S20, S21, S26, S27', and S29.

P38234	RFS1_YEAST	Protein RFS1	19064668	Plasma membrane microdomains regulate turnover of transport proteins in yeast.

Q9P6N3	SHE9_SCHPO	Sensitive to high expression protein 9 homolog, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9FN02	PPP7_ARATH	Serine/threonine-protein phosphatase 7	12724537	PP7 is a positive regulator of blue light signaling in Arabidopsis.

P00854	ATP6_YEAST	ATP synthase subunit a	2894987	NH2-terminal sequence of the isolated yeast ATP synthase subunit 6 reveals post-translational cleavage.

Q09736	CP51_SCHPO	Lanosterol 14-alpha demethylase erg11	17276356	Dap1/PGRMC1 binds and regulates cytochrome P450 enzymes.

P43687	HMX2_MOUSE	Homeobox protein HMX2	11748138	Hmx2 homeobox gene control of murine vestibular morphogenesis.

P38398	BRCA1_HUMAN	Breast cancer type 1 susceptibility protein	17643121	CCDC98 targets BRCA1 to DNA damage sites.

Q9H221	ABCG8_HUMAN	ATP-binding cassette sub-family G member 8	11099417	Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters.

O15551	CLD3_HUMAN	Claudin-3	9334247	Clostridium perfringens enterotoxin utilizes two structurally related membrane proteins as functional receptors in vivo.

P35568	IRS1_HUMAN	Insulin receptor substrate 1	1311924	Cloning and increased expression of an insulin receptor substrate-1- like gene in human hepatocellular carcinoma.

P39905	GDNF_HUMAN	Glial cell line-derived neurotrophic factor	8988018	Glial cell line-derived neurotrophic factor: selective reduction of the intermolecular disulfide linkage and characterization of its disulfide structure.

Q8IVH8	M4K3_HUMAN	Mitogen-activated protein kinase kinase kinase kinase 3	9275185	Activation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinase.

P27777	HS16A_ORYSJ	16.9 kDa class I heat shock protein 1	10548530	Molecular characterization of Oryza sativa 16.9 kDa heat shock protein.

Q6IMB1	RSLBA_MOUSE	Ras-like protein family member 11A	20168301	Chromatin association and regulation of rDNA transcription by the Ras-family protein RasL11a.

Q13829	BACD2_HUMAN	BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2	1370465	Characterization of a novel tumor necrosis factor-alpha-induced endothelial primary response gene.

P53965	SIW14_YEAST	Tyrosine-protein phosphatase SIW14	15020461	A synthetic lethal screen identifies a role for the cortical actin patch/endocytosis complex in the response to nutrient deprivation in Saccharomyces cerevisiae.

Q9SAD4	ESR1_ARATH	Ethylene-responsive transcription factor ESR1	11752375	Overexpression of Arabidopsis ESR1 induces initiation of shoot regeneration.

Q09413	ELOA1_CAEEL	Transcription elongation factor B polypeptide 3	8896449	The inducible elongin A elongation activation domain: structure, function and interaction with the elongin BC complex.

Q5TJ65	VASP_DICDI	Protein VASP homolog	16675552	The bundling activity of vasodilator-stimulated phosphoprotein is required for filopodium formation.

P36193	DROS_DROME	Drosocin	9736738	Differential display of peptides induced during the immune response of Drosophila: a matrix-assisted laser desorption ionization time-of- flight mass spectrometry study.

Q9H1D0	TRPV6_HUMAN	Transient receptor potential cation channel subfamily V member 6	15184369	Ca2+ dependence of the Ca2+-selective TRPV6 channel.

Q9Z0Y7	IRS4_MOUSE	Insulin receptor substrate 4	12052866	SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation.

O75170	PP6R2_HUMAN	Serine/threonine-protein phosphatase 6 regulatory subunit 2	18186651	Protein phosphatase 6 regulatory subunits composed of ankyrin repeat domains.

O95999	BCL10_HUMAN	B-cell lymphoma/leukemia 10	10400625	c-E10 is a caspase-recruiting domain-containing protein that interacts with components of death receptors signaling pathway and activates nuclear factor-kappaB.

P14416	DRD2_HUMAN	D(2) dopamine receptor	2531656	The dopamine D2 receptor: two molecular forms generated by alternative splicing.

P38724	ARN2_YEAST	Siderophore iron transporter ARN2	10816729	Identification of a fungal triacetylfusarinine C siderophore transport gene (TAF1) in Saccharomyces cerevisiae as a member of the major facilitator superfamily.

P51521	OVO_DROME	Protein ovo	11290304	Drosophila OVO regulates ovarian tumor transcription by binding unusually near the transcription start site.

O88447	KLC1_MOUSE	Kinesin light chain 1	9624122	Two kinesin light chain genes in mice. Identification and characterization of the encoded proteins.

Q8RWN9	OPD22_ARATH	Dihydrolipoyllysine-residue acetyltransferase component 2 of pyruvate dehydrogenase complex, mitochondrial	14764908	Lipoic acid-dependent oxidative catabolism of alpha-keto acids in mitochondria provides evidence for branched-chain amino acid catabolism in Arabidopsis.

O94278	THI5_SCHPO	Thiamine repressible genes regulatory protein thi5	16874521	Joint regulation of the nmt1 promoter and sporulation by Thi1 and Thi5 in Schizosaccharomyces pombe.

Q38906	TOC34_ARATH	Translocase of chloroplast 34, chloroplastic	12938931	Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis.

P32598	PP12_YEAST	Serine/threonine-protein phosphatase PP1-2	10975519	Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes.

P62069	UBP46_MOUSE	Ubiquitin carboxyl-terminal hydrolase 46	19465912	Usp46 is a quantitative trait gene regulating mouse immobile behavior in the tail suspension and forced swimming tests.

P36544	ACHA7_HUMAN	Neuronal acetylcholine receptor subunit alpha-7	8145738	Human alpha 7 acetylcholine receptor: cloning of the alpha 7 subunit from the SH-SY5Y cell line and determination of pharmacological properties of native receptors and functional alpha 7 homomers expressed in Xenopus oocytes.

O42173	PV1_XENLA	Homeobox protein pv.1	9405105	The homeobox gene PV.1 mediates specification of the prospective neural ectoderm in Xenopus embryos.

Q8ZNR3	SOPA_SALTY	E3 ubiquitin-protein ligase SopA	17076670	The inflammation-associated Salmonella SopA is a HECT-like E3 ubiquitin ligase.

Q9Y6M1	IF2B2_HUMAN	Insulin-like growth factor 2 mRNA-binding protein 2	20080952	ZBP1 recognition of beta-actin zipcode induces RNA looping.

Q05021	TAF7_YEAST	Transcription initiation factor TFIID subunit 7	10788514	Identification of two novel TAF subunits of the yeast Saccharomyces cerevisiae TFIID complex.

Q96CA5	BIRC7_HUMAN	Baculoviral IAP repeat-containing protein 7	11162435	KIAP, a novel member of the inhibitor of apoptosis protein family.

Q9NBK5	TRC_DROME	Serine/threonine-protein kinase tricorner	15479641	Control of dendritic branching and tiling by the Tricornered- kinase/Furry signaling pathway in Drosophila sensory neurons.

O09117	SYPL1_MOUSE	Synaptophysin-like protein 1	8707851	Pantophysin is a ubiquitously expressed synaptophysin homologue and defines constitutive transport vesicles.

Q8VHT7	TF3A_MOUSE	Transcription factor IIIA	11814676	cDNA cloning, DNA binding, and evolution of mammalian transcription factor IIIA.

Q9NQX7	ITM2C_HUMAN	Integral membrane protein 2C	18452648	BRI3 associates with SCG10 and attenuates NGF-induced neurite outgrowth in PC12 cells.

Q9USL3	SYIM_SCHPO	Isoleucyl-tRNA synthetase, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P19544	WT1_HUMAN	Wilms tumor protein	15520190	SUMO-1 modification of the Wilms' tumor suppressor WT1.

P25642	IMG2_YEAST	54S ribosomal protein IMG2, mitochondrial	12392552	Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components.

P22103	PNEU_HUMAN	Pneumadin	2274681	Pneumadin: a new lung peptide which triggers antidiuresis.

Q38895	SUP_ARATH	Transcriptional regulator SUPERMAN	7477325	Role of SUPERMAN in maintaining Arabidopsis floral whorl boundaries.

P38875	GPI16_YEAST	GPI transamidase component GPI16	11598210	The GPI transamidase complex of Saccharomyces cerevisiae contains Gaa1p, Gpi8p, and Gpi16p.

Q8IWL3	HSC20_HUMAN	Iron-sulfur cluster co-chaperone protein HscB, mitochondrial	12938016	Identification of a novel candidate gene in the iron-sulfur pathway implicated in ataxia-susceptibility: human gene encoding HscB, a J- type co-chaperone.

Q12800	TFCP2_HUMAN	Alpha-globin transcription factor CP2	8157699	Characterization of the genomic structure, chromosomal location, promoter, and development expression of the alpha-globin transcription factor CP2.

P48426	PI42A_HUMAN	Phosphatidylinositol-5-phosphate 4-kinase type-2 alpha	7639683	The cloning and sequence of the C isoform of PtdIns4P 5-kinase.

Q9UQ84	EXO1_HUMAN	Exonuclease 1	15886194	RECQ1 helicase interacts with human mismatch repair factors that regulate genetic recombination.

Q8CJI4	H1FNT_MOUSE	Testis-specific H1 histone	15710904	Polar nuclear localization of H1T2, a histone H1 variant, required for spermatid elongation and DNA condensation during spermiogenesis.

O14727	APAF_HUMAN	Apoptotic protease-activating factor 1	10441496	Three new types of Apaf-1 in mammalian cells.

P46654	RSSA2_YEAST	40S ribosomal protein S0-B	14627813	Ribosomal proteins Rps0 and Rps21 of Saccharomyces cerevisiae have overlapping functions in the maturation of the 3' end of 18S rRNA.

Q9BZF9	UACA_HUMAN	Uveal autoantigen with coiled-coil domains and ankyrin repeats	11162650	Identification of a novel autoantigen UACA in patients with panuveitis.

P43897	EFTS_HUMAN	Elongation factor Ts, mitochondrial	7615523	Cloning and expression of mitochondrial translational elongation factor Ts from bovine and human liver.

Q7L1T6	NB5R4_HUMAN	Cytochrome b5 reductase 4	10611283	Identification of a cytochrome b-type NAD(P)H oxidoreductase ubiquitously expressed in human cells.

Q7YSI9	UNC53_CAEEL	Adapter protein unc-53	12091307	unc-53 controls longitudinal migration in C. elegans.

P12429	ANXA3_HUMAN	Annexin A3	2138632	Purification and characterization of an abundant cytosolic protein from human neutrophils that promotes Ca2(+)-dependent aggregation of isolated specific granules.

O23492	INT4_ARATH	Inositol transporter 4	16603666	Arabidopsis INOSITOL TRANSPORTER4 mediates high-affinity H+ symport of myoinositol across the plasma membrane.

Q9XYZ5	DDB1_DROME	DNA damage-binding protein 1	18381890	WD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1-CUL4-ROC1 ligase.

Q09884	DCR1_SCHPO	Protein Dicer	12482946	Dicer is required for chromosome segregation and gene silencing in fission yeast cells.

P84156	DEFN_ARCDE	Defensin ARD1	14978308	Lead optimization of antifungal peptides with 3D NMR structures analysis.

Q99LX0	PARK7_MOUSE	Protein DJ-1	11223268	Molecular cloning of human and mouse DJ-1 genes and identification of Sp1-dependent activation of the human DJ-1 promoter.

P29268	CTGF_MOUSE	Connective tissue growth factor	1888698	Structure, mapping, and expression of fisp-12, a growth factor- inducible gene encoding a secreted cysteine-rich protein.

Q6PEE3	RIR2B_MOUSE	Ribonucleoside-diphosphate reductase subunit M2 B	12858174	Impaired function of p53R2 in Rrm2b-null mice causes severe renal failure through attenuation of dNTP pools.

Q06630	MHR1_YEAST	Mitochondrial homologous recombination protein 1	12034822	The yeast protein Xtc1 functions as a direct transcriptional repressor.

O88904	HIPK1_MOUSE	Homeodomain-interacting protein kinase 1	12529400	Homeodomain-interacting protein kinase 1 modulates Daxx localization, phosphorylation, and transcriptional activity.

O15195	VILL_HUMAN	Villin-like protein	9179494	Sequence analysis of a 685-kb genomic region on chromosome 3p22-p21.3 that is homozygously deleted in a lung carcinoma cell line.

P79051	RHP16_SCHPO	ATP-dependent helicase rhp16	8879272	Cloning of Schizosaccharomyces pombe rph16+, a gene homologous to the Saccharomyces cerevisiae RAD16 gene.

Q9P032	NDUF4_HUMAN	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4	18179882	C6ORF66 is an assembly factor of mitochondrial complex I.

P97309	MESP1_MOUSE	Mesoderm posterior protein 1	8787751	MesP1: a novel basic helix-loop-helix protein expressed in the nascent mesodermal cells during mouse gastrulation.

Q6NWD4	TIM50_DANRE	Mitochondrial import inner membrane translocase subunit TIM50	15044455	Tim50, a component of the mitochondrial translocator, regulates mitochondrial integrity and cell death.

P25765	CHI12_ORYSJ	Chitinase 12	2034221	Isolation and characterization of a rice gene encoding a basic chitinase.

O95433	AHSA1_HUMAN	Activator of 90 kDa heat shock protein ATPase homolog 1	12604615	Aha1 binds to the middle domain of Hsp90, contributes to client protein activation, and stimulates the ATPase activity of the molecular chaperone.

Q8JIT7	FAST3_XENLA	Forkhead activin signal transducer 3	14729957	Recognition of phosphorylated-Smad2-containing complexes by a novel Smad interaction motif.

Q6TA25	FGOP2_RAT	FGFR1 oncogene partner 2 homolog	14527947	Oral fibroblast expression of wound-inducible transcript 3.0 (wit3.0) accelerates the collagen gel contraction in vitro.

P01106	MYC_HUMAN	Myc proto-oncogene protein	17558397	The ubiquitin-specific protease USP28 is required for MYC stability.

Q9SF85	ADK1_ARATH	Adenosine kinase 1	11115893	Adenosine kinase of Arabidopsis. Kinetic properties and gene expression.

P62775	MTPN_RAT	Myotrophin	8144589	Murine cerebellar neurons express a novel gene encoding a protein related to cell cycle control and cell fate determination proteins.

Q9FHW7	SKP1B_ARATH	SKP1-like protein 1B	12970487	Members of the Arabidopsis-SKP1-like gene family exhibit a variety of expression patterns and may play diverse roles in Arabidopsis.

P29122	PCSK6_HUMAN	Proprotein convertase subtilisin/kexin type 6	8906861	Functional analysis of human PACE4-A and PACE4-C isoforms: identification of a new PACE4-CS isoform.

Q9UBX3	DIC_HUMAN	Mitochondrial dicarboxylate carrier	10585886	Organization and sequence of the gene for the human mitochondrial dicarboxylate carrier: evolution of the carrier family.

P39006	PSD1_YEAST	Phosphatidylserine decarboxylase proenzyme 1, mitochondrial	8407984	Phosphatidylserine decarboxylase from Saccharomyces cerevisiae. Isolation of mutants, cloning of the gene, and creation of a null allele.

P33438	GLT_DROME	Glutactin	2108864	Glutactin, a novel Drosophila basement membrane-related glycoprotein with sequence similarity to serine esterases.

Q54WX4	AURK_DICDI	Probable serine/threonine-protein kinase aurK	16339076	Contractile ring-independent localization of DdINCENP, a protein important for spindle stability and cytokinesis.

Q9D074	MGRN1_MOUSE	E3 ubiquitin-protein ligase MGRN1	12560552	Spongiform degeneration in mahoganoid mutant mice.

O94436	TAF14_SCHPO	Transcription initiation factor TFIID subunit 14	18622392	Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast.

P40357	SEC9_YEAST	Protein transport protein SEC9	7954793	Sec9 is a SNAP-25-like component of a yeast SNARE complex that may be the effector of Sec4 function in exocytosis.

Q9Y5Y4	GPR44_HUMAN	Putative G-protein coupled receptor 44	10036181	Discovery of three novel orphan G-protein-coupled receptors.

O74971	ATG5_SCHPO	Autophagy protein 5	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

Q92823	NRCAM_HUMAN	Neuronal cell adhesion molecule	11483367	The complete sequence of the human locus for NgCAM-related cell adhesion molecule reveals a novel alternative exon in chick and man and conserved genomic organization for the L1 subfamily.

Q12226	AYT1_YEAST	Trichothecene 3-O-acetyltransferase	12478589	The identification of the Saccharomyces cerevisiae gene AYT1(ORF- YLL063c) encoding an acetyltransferase.

Q8WX92	NELFB_HUMAN	Negative elongation factor B	11739404	BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations.

Q9Z136	TSC1_RAT	Hamartin	9809973	Hamartin, the product of the tuberous sclerosis 1 (TSC1) gene, interacts with tuberin and appears to be localized to cytoplasmic vesicles.

P53799	FDFT_ARATH	Squalene synthase	7892265	Cloning, expression, and characterization of cDNAs encoding Arabidopsis thaliana squalene synthase.

O77741	NRAM1_PIG	Natural resistance-associated macrophage protein 1	10678911	Cloning of porcine NRAMP1 and its induction by lipopolysaccharide, tumor necrosis factor alpha, and interleukin-1beta: role of CD14 and mitogen-activated protein kinases.

O60883	ETBR2_HUMAN	Endothelin B receptor-like protein 2	9539149	A new family of orphan G protein-coupled receptors predominantly expressed in the brain.

P17098	ZNF8_HUMAN	Zinc finger protein 8	2106481	cDNA isolation, expression analysis, and chromosomal localization of two human zinc finger genes.

P36626	REC8_SCHPO	Meiotic recombination protein rec8	16325576	The kinetochore protein moa1 enables cohesion-mediated monopolar attachment at meiosis I.

Q01780	EXOSX_HUMAN	Exosome component 10	15231747	A protein interaction framework for human mRNA degradation.

P16219	ACADS_HUMAN	Short-chain specific acyl-CoA dehydrogenase, mitochondrial	2565344	Molecular cloning and nucleotide sequence of complementary DNAs encoding human short chain acyl-coenzyme A dehydrogenase and the study of the molecular basis of human short chain acyl-coenzyme A dehydrogenase deficiency.

P58908	LECA_DIORO	Lectin alpha chain	10082964	Molecular characterization and crystallization of Diocleinae lectins.

P06839	RAD3_YEAST	DNA repair helicase RAD3	8631896	Reconstitution of TFIIH and requirement of its DNA helicase subunits, Rad3 and Rad25, in the incision step of nucleotide excision repair.

Q99102	MUC4_HUMAN	Mucin-4	10920259	Human MUC4 mucin cDNA and its variants in pancreatic carcinoma.

Q54ES8	YKT6_DICDI	Putative synaptobrevin homolog YKT6	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q9LVM1	AB25B_ARATH	ABC transporter B family member 25, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q12117	MRH1_YEAST	Protein MRH1	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q8C180	FRS2_MOUSE	Fibroblast growth factor receptor substrate 2	9182757	A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway.

Q9VEZ5	IKKB_DROME	Inhibitor of nuclear factor kappa-B kinase subunit beta	11156609	The antibacterial arm of the Drosophila innate immune response requires an IkappaB kinase.

Q15654	TRIP6_HUMAN	Thyroid receptor-interacting protein 6	14688263	TRIP6 enhances lysophosphatidic acid-induced cell migration by interacting with the lysophosphatidic acid 2 receptor.

P16884	NFH_RAT	Neurofilament heavy polypeptide	2230956	Transfected rat high-molecular-weight neurofilament (NF-H) coassembles with vimentin in a predominantly nonphosphorylated form.

Q27571	NOS_DROME	Nitric oxide synthase	7568075	Molecular and biochemical characterization of dNOS: a Drosophila Ca2+/calmodulin-dependent nitric oxide synthase.

Q9LV58	MBF1C_ARATH	Multiprotein-bridging factor 1c	14988493	Three Arabidopsis MBF1 homologs with distinct expression profiles play roles as transcriptional co-activators.

Q9QYV0	ADA15_RAT	Disintegrin and metalloproteinase domain-containing protein 15	11102971	Cellular localization of the disintegrin CRII-7/rMDC15 mRNA in rat PNS and CNS and regulated expression in postnatal development and after nerve injury.

Q14197	ICT1_HUMAN	Peptidyl-tRNA hydrolase ICT1, mitochondrial	20186120	A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome.

Q39234	TGA3_ARATH	Transcription factor TGA3	8003690	TGA3 is a distinct member of the TGA family of bZIP transcription factors in Arabidopsis thaliana.

P83941	ELOC_RAT	Transcription elongation factor B polypeptide 1	8202474	Molecular cloning of an essential subunit of RNA polymerase II elongation factor SIII.

P42892	ECE1_HUMAN	Endothelin-converting enzyme 1	9915973	A loss-of-function mutation in the endothelin-converting enzyme 1 (ECE-1) associated with Hirschsprung disease, cardiac defects, and autonomic dysfunction.

P55072	TERA_HUMAN	Transitional endoplasmic reticulum ATPase	17314412	The RBCC gene RFP2 (Leu5) encodes a novel transmembrane E3 ubiquitin ligase involved in ERAD.

P42844	ZIM17_YEAST	Mitochondrial protein import protein ZIM17	14562095	Global analysis of protein localization in budding yeast.

P46989	ATG27_YEAST	Autophagy-related protein 27	12186856	Novel PtdIns(3)P-binding protein Etf1 functions as an effector of the Vps34 PtdIns 3-kinase in autophagy.

Q96QF0	RAB3I_HUMAN	Rab-3A-interacting protein	12007189	The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP.

P53622	COPA_YEAST	Coatomer subunit alpha	17101773	Involvement of specific COPI subunits in protein sorting from the late endosome to the vacuole in yeast.

Q9NHC3	CED2_CAEEL	Cell death abnormality protein 2	6857247	Mutations affecting programmed cell deaths in the nematode Caenorhabditis elegans.

Q05048	CSTF1_HUMAN	Cleavage stimulation factor subunit 1	10477523	Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50.

O35425	BOK_MOUSE	Bcl-2-related ovarian killer protein	9535847	Mtd, a novel Bcl-2 family member activates apoptosis in the absence of heterodimerization with Bcl-2 and Bcl-XL.

O75339	CILP1_HUMAN	Cartilage intermediate layer protein 1	12746903	One of two chondrocyte-expressed isoforms of cartilage intermediate- layer protein functions as an insulin-like growth factor 1 antagonist.

Q3E705	EFG1P_YEAST	rRNA-processing protein EFG1	14562095	Global analysis of protein localization in budding yeast.

O43674	NDUB5_HUMAN	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

Q23K29	TTL3D_TETTH	Tubulin glycylase 3D	19531357	TTLL3 Is a tubulin glycine ligase that regulates the assembly of cilia.

P36616	DSK1_SCHPO	Protein kinase dsk1	8485317	A mitotic role for a novel fission yeast protein kinase dsk1 with cell cycle stage dependent phosphorylation and localization.

Q58576	PAN_METJA	Proteasome-activating nucleotidase	10692374	Biochemical and physical properties of the Methanococcus jannaschii 20S proteasome and PAN, a homolog of the ATPase (Rpt) subunits of the eucaryal 26S proteasome.

Q05586	NMDZ1_HUMAN	Glutamate [NMDA] receptor subunit zeta-1	7685113	Molecular cloning, functional expression, and pharmacological characterization of an N-methyl-D-aspartate receptor subunit from human brain.

P51587	BRCA2_HUMAN	Breast cancer type 2 susceptibility protein	15967112	WDRPUH, a novel WD-repeat-containing protein, is highly expressed in human hepatocellular carcinoma and involved in cell proliferation.

Q06705	CSR1_YEAST	Phosphatidylinositol transfer protein CSR1	10679005	Sbe2p and sbe22p, two homologous Golgi proteins involved in yeast cell wall formation.

Q9UBI1	COMD3_HUMAN	COMM domain-containing protein 3	15799966	COMMD proteins, a novel family of structural and functional homologs of MURR1.

Q9VNA8	DONS_DROME	Protein downstream neighbor of son homolog	15854909	humpty dumpty is required for developmental DNA amplification and cell proliferation in Drosophila.

Q9Y618	NCOR2_HUMAN	Nuclear receptor corepressor 2	11739383	Isolation and characterization of a novel class II histone deacetylase, HDAC10.

Q09330	MLO3_SCHPO	mRNA export protein mlo3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q95017	UBC9_CAEEL	SUMO-conjugating enzyme UBC9	15689373	Sumoylation of LIN-1 promotes transcriptional repression and inhibition of vulval cell fates.

P84550	SKOR1_HUMAN	SKI family transcriptional corepressor 1	17292623	Fussel-15, a novel Ski/Sno homolog protein, antagonizes BMP signaling.

Q94B60	CLPP4_ARATH	ATP-dependent Clp protease proteolytic subunit 4, chloroplastic	17241447	The chloroplast protease subunit ClpP4 is a substrate of the E3 ligase AtCHIP and plays an important role in chloroplast function.

Q9Z320	K1C27_MOUSE	Keratin, type I cytoskeletal 27	17920809	Mutations in the helix termination motif of mouse type I IRS keratin genes impair the assembly of keratin intermediate filament.

Q63537	SYN2_RAT	Synapsin-2	11867766	Neuronal nitric-oxide synthase localization mediated by a ternary complex with synapsin and CAPON.

P53552	THO2_YEAST	THO complex subunit 2	12093753	The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability.

Q1JQ73	ELV1A_XENLA	ELAV-like protein 1-A	18930026	ElrA and AUF1 differentially bind cyclin B2 mRNA.

Q9LKL2	APRR1_ARATH	Two-component response regulator-like APRR1	18055606	PRR3 Is a vascular regulator of TOC1 stability in the Arabidopsis circadian clock.

Q9UBH6	XPR1_HUMAN	Xenotropic and polytropic retrovirus receptor 1	9988277	Receptors for polytropic and xenotropic mouse leukaemia viruses encoded by a single gene at Rmc1.

P32558	SPT16_YEAST	FACT complex subunit SPT16	12952948	Multiple Nhp6 molecules are required to recruit Spt16-Pob3 to form yFACT complexes and to reorganize nucleosomes.

P42453	RUBR_ACIAD	Rubredoxin	10400587	The genes rubA and rubB for alkane degradation in Acinetobacter sp. strain ADP1 are in an operon with estB, encoding an esterase, and oxyR.

Q68G30	KLC3_RAT	Kinesin light chain 3	11319135	Kinesin light-chain KLC3 expression in testis is restricted to spermatids.

O58307	ALAXS_PYRHO	Alanyl-tRNA editing protein AlaX-S	16087889	Molecular basis of alanine discrimination in editing site.

P37173	TGFR2_HUMAN	TGF-beta receptor type-2	11850637	Crystal structure of the human TbetaR2 ectodomain--TGF-beta3 complex.

P41091	IF2G_HUMAN	Eukaryotic translation initiation factor 2 subunit 3	8106381	Translation initiation factor eIF-2. Cloning and expression of the human cDNA encoding the gamma-subunit.

P28659	CELF1_MOUSE	CUGBP Elav-like family member 1	16931514	Age-specific CUGBP1-eIF2 complex increases translation of CCAAT/enhancer-binding protein beta in old liver.

P56703	WNT3_HUMAN	Proto-oncogene Wnt-3	14872406	Homozygous WNT3 mutation causes tetra-amelia in a large consanguineous family.

Q24572	CAF1_DROME	Probable histone-binding protein Caf1	15545624	Identification of a Drosophila Myb-E2F2/RBF transcriptional repressor complex.

Q23064	UNC83_CAEEL	Nuclear migration protein unc-83	11748140	unc-83 encodes a novel component of the nuclear envelope and is essential for proper nuclear migration.

Q55E26	GXCB_DICDI	Rac guanine nucleotide exchange factor B	16781009	Trix, a novel Rac guanine-nucleotide exchange factor from Dictyostelium discoideum is an actin-binding protein and accumulates at endosomes.

Q8W4J8	TIF7_ARATH	Protein TIFY 7	17637677	JAZ repressor proteins are targets of the SCF(COI1) complex during jasmonate signalling.

Q09892	HOG1_SCHPO	Mitogen-activated protein kinase sty1	16278445	Stress-activated protein kinase pathway functions to support protein synthesis and translational adaptation in response to environmental stress in fission yeast.

Q62315	JARD2_MOUSE	Protein Jumonji	15870077	Jumonji regulates cardiomyocyte proliferation via interaction with retinoblastoma protein.

P23919	KTHY_HUMAN	Thymidylate kinase	8024690	Human dTMP kinase: gene expression and enzymatic activity coinciding with cell cycle progression and cell growth.

Q7XUN2	MAD17_ORYSJ	MADS-box transcription factor 17	19820190	MOSAIC FLORAL ORGANS1, an AGL6-like MADS box gene, regulates floral organ identity and meristem fate in rice.

Q8TCC7	S22A8_HUMAN	Solute carrier family 22 member 8	10049739	Molecular cloning and characterization of two novel human renal organic anion transporters (hOAT1 and hOAT3).

Q7SZS1	SX21A_DANRE	Transcription factor Sox-21-A	15037315	Ectopic expression and knockdown of a zebrafish sox21 reveal its role as a transcriptional repressor in early development.

Q90VV1	HES4B_XENLA	Transcription factor HES-4-B	19253409	Xhairy2 functions in Xenopus lens development by regulating p27(xic1) expression.

Q08634	YO238_YEAST	Uncharacterized protein YOR238W	14562095	Global analysis of protein localization in budding yeast.

P50520	VPS34_SCHPO	Phosphatidylinositol 3-kinase vps34	7772832	Phosphatidylinositol-3 kinase in fission yeast: a possible role in stress responses.

Q96RU2	UBP28_HUMAN	Ubiquitin carboxyl-terminal hydrolase 28	17558397	The ubiquitin-specific protease USP28 is required for MYC stability.

O15492	RGS16_HUMAN	Regulator of G-protein signaling 16	9469939	Cloning of a retinally abundant regulator of G-protein signaling (RGS-r/RGS16): genomic structure and chromosomal localization of the human gene.

P53743	ESF2_YEAST	Pre-rRNA-processing protein ESF2	16772403	The nucleolar protein Esf2 interacts directly with the DExD/H box RNA helicase, Dbp8, to stimulate ATP hydrolysis.

O70200	AIF1_MOUSE	Allograft inflammatory factor 1	14756805	Microglia/macrophage-specific protein Iba1 binds to fimbrin and enhances its actin-bundling activity.

Q9Y709	SKP1_SCHPO	Suppressor of kinetochore protein 1	12511573	Skp1 and the F-box protein Pof6 are essential for cell separation in fission yeast.

P54275	MSH2_RAT	DNA mismatch repair protein Msh2	9034308	Cloning of the cDNA encoding rat homologue of the mismatch repair gene MSH2 and its expression during spermatogenesis.

Q9ULW0	TPX2_HUMAN	Targeting protein for Xklp2	14580337	Structural basis of Aurora-A activation by TPX2 at the mitotic spindle.

P49888	ST1E1_HUMAN	Estrogen sulfotransferase	8185618	Human liver estrogen sulfotransferase: identification by cDNA cloning and expression.

Q8W4P1	CDKC2_ARATH	Cyclin-dependent kinase C-2	12678503	Novel complexes of cyclin-dependent kinases and a cyclin-like protein from Arabidopsis thaliana with a function unrelated to cell division.

Q8Q0A4	ALAXM_METMA	Alanyl-tRNA editing protein AlaX-M	18723508	Natural homolog of tRNA synthetase editing domain rescues conditional lethality caused by mistranslation.

P23798	PCGF2_MOUSE	Polycomb group RING finger protein 2	8625838	A role for mel-18, a Polycomb group-related vertebrate gene, during the anteroposterior specification of the axial skeleton.

Q09826	SDS23_SCHPO	Protein sds23/moc1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P07257	QCR2_YEAST	Cytochrome b-c1 complex subunit 2, mitochondrial	10873857	Structure at 2.3 A resolution of the cytochrome bc1 complex from the yeast Saccharomyces cerevisiae co-crystallized with an antibody Fv fragment.

P47979	ZFS1_SCHPO	Zinc finger protein zfs1	18042546	Characterization of zfs1 as an mRNA-binding and -destabilizing protein in Schizosaccharomyces pombe.

P92958	KIN11_ARATH	SNF1-related protein kinase catalytic subunit alpha KIN11	10220464	Regulatory interaction of PRL1 WD protein with Arabidopsis SNF1-like protein kinases.

P34808	MEI1_CAEEL	Meiotic spindle formation protein mei-1	8027178	Localization of the mei-1 gene product of Caenorhaditis elegans, a meiotic-specific spindle component.

Q9Y4X3	CCL27_HUMAN	C-C motif chemokine 27	10588729	CTACK, a skin-associated chemokine that preferentially attracts skin- homing memory T cells.

P43246	MSH2_HUMAN	DNA mismatch repair protein Msh2	9788596	Human exonuclease I interacts with the mismatch repair protein hMSH2.

Q9VVV9	NKD_DROME	Protein naked cuticle	12354775	Zinc-dependent interaction between dishevelled and the Drosophila Wnt antagonist naked cuticle.

P39102	XDJ1_YEAST	DnaJ protein homolog XDJ1	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

P62277	RS13_HUMAN	40S ribosomal protein S13	8332508	Cloning and analysis of the human S13 ribosomal protein cDNA.

P08964	MYO1_YEAST	Myosin-1	3322809	The yeast MYO1 gene encoding a myosin-like protein required for cell division.

Q12511	PP2C5_YEAST	Protein phosphatase 2C homolog 5	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P35207	SKI2_YEAST	Antiviral helicase SKI2	9482746	The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex.

Q13489	BIRC3_HUMAN	Baculoviral IAP repeat-containing protein 3	8548810	The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins.

P87231	MUS81_SCHPO	Crossover junction endonuclease mus81	14527419	The endogenous Mus81-Eme1 complex resolves Holliday junctions by a nick and counternick mechanism.

P40240	CD9_MOUSE	CD9 antigen	10700183	The gamete fusion process is defective in eggs of Cd9-deficient mice.

Q9UER7	DAXX_HUMAN	Death domain-associated protein 6	11003656	Inhibition of Daxx-mediated apoptosis by heat shock protein 27.

Q9YGL1	SPD1B_XENLA	Speedy protein 1-B	16418484	Regulated Pumilio-2 binding controls RINGO/Spy mRNA translation and CPEB activation.

P26043	RADI_MOUSE	Radixin	12554651	Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex.

P30777	GPI10_YEAST	GPI mannosyltransferase 3	9639537	GPI anchor biosynthesis in yeast: phosphoethanolamine is attached to the alpha1,4-linked mannose of the complete precursor glycophospholipid.

Q8RWU4	ATML1_ARATH	Homeobox-leucine zipper protein MERISTEM L1	12505995	Regulation of shoot epidermal cell differentiation by a pair of homeodomain proteins in Arabidopsis.

O15392	BIRC5_HUMAN	Baculoviral IAP repeat-containing protein 5	18591255	A survivin-ran complex regulates spindle formation in tumor cells.

Q5AVY9	CUTI2_EMENI	Cutinase 2	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

P08659	LUCI_PHOPY	Luciferin 4-monooxygenase	3554235	Firefly luciferase is targeted to peroxisomes in mammalian cells.

Q27368	E2F_DROME	Transcription factor E2f	8114698	Functional properties of a Drosophila homolog of the E2F1 gene.

A5H447	ZYX_XENLA	Zyxin	18297730	The LIM-domain protein zyxin binds the homeodomain factor Xanf1/Hesx1 and modulates its activity in the anterior neural plate of Xenopus laevis embryo.

P03129	VE7_HPV16	Protein E7	12072504	Translational regulation of human papillomavirus type 16 E7 mRNA by the peptide SEQIKA, shared by rabbit alpha(1)-globin and human cytokeratin 7.

P28870	FKBP_CANAL	FK506-binding protein 1	1563628	Cloning and sequence analysis of a rapamycin-binding protein-encoding gene (RBP1) from Candida albicans.

O74736	ING2_SCHPO	Chromatin modification-related protein png2	17450151	Distinct roles of HDAC complexes in promoter silencing, antisense suppression and DNA damage protection.

P23566	UBC2_SCHPO	Ubiquitin-conjugating enzyme E2 2	2184030	The rhp6+ gene of Schizosaccharomyces pombe: a structural and functional homolog of the RAD6 gene from the distantly related yeast Saccharomyces cerevisiae.

O74954	YJC8_SCHPO	Uncharacterized protein C736.08	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q92954	PRG4_HUMAN	Proteoglycan 4	10545950	CACP, encoding a secreted proteoglycan, is mutated in camptodactyly- arthropathy-coxa vara-pericarditis syndrome.

Q9JKX3	TFR2_MOUSE	Transferrin receptor protein 2	10681454	Transferrin receptor 2: continued expression in mouse liver in the face of iron overload and in hereditary hemochromatosis.

Q96T55	KCNKG_HUMAN	Potassium channel subfamily K member 16	11263999	Genomic and functional characteristics of novel human pancreatic 2P domain K(+) channels.

Q0E940	EIF3B_DROME	Eukaryotic translation initiation factor 3 subunit B	17392269	The essential Drosophila ATP-binding cassette domain protein, pixie, binds the 40 S ribosome in an ATP-dependent manner and is required for translation initiation.

Q8RYC8	ARFS_ARATH	Auxin response factor 19	17259263	ARF7 and ARF19 regulate lateral root formation via direct activation of LBD/ASL genes in Arabidopsis.

O64425	RMA1_ARATH	E3 ubiquitin-protein ligase RMA1	11329381	Rma1, a novel type of RING finger protein conserved from Arabidopsis to human, is a membrane-bound ubiquitin ligase.

O74821	DRE2_SCHPO	Fe-S cluster assembly protein dre2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P98095	FBLN2_HUMAN	Fibulin-2	7806230	Fibulin-2 (FBLN2): human cDNA sequence, mRNA expression, and mapping of the gene on human and mouse chromosomes.

Q9Y6I8	PXMP4_HUMAN	Peroxisomal membrane protein 4	10366717	Identification of a 24 kDa intrinsic membrane protein from mammalian peroxisomes.

Q9UBU8	MO4L1_HUMAN	Mortality factor 4-like protein 1	14966270	Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans.

O02372	OB76A_DROME	General odorant-binding protein lush	9755202	LUSH odorant-binding protein mediates chemosensory responses to alcohols in Drosophila melanogaster.

Q6PAL1	DRAXI_MOUSE	Draxin	19150847	Draxin, a repulsive guidance protein for spinal cord and forebrain commissures.

Q6NPM8	IMPL2_ARATH	Phosphatase IMPL2, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q7TNG8	LDHD_MOUSE	Probable D-lactate dehydrogenase, mitochondrial	12127981	Identification of putative mammalian D-lactate dehydrogenase enzymes.

A8K0Z3	WASH1_HUMAN	WAS protein family homolog 1	19922874	A FAM21-containing WASH complex regulates retromer-dependent sorting.

P83732	RL24_RAT	60S ribosomal protein L24	8048931	The primary structure of rat ribosomal protein L24.

O13800	RDL1_SCHPO	DNA repair protein rdl1	16710300	Sws1 is a conserved regulator of homologous recombination in eukaryotic cells.

O94720	YCF8_SCHPO	GATA zinc finger domain-containing protein C1393.08	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NYL5	CP39A_HUMAN	24-hydroxycholesterol 7-alpha-hydroxylase	10748047	Expression cloning of an oxysterol 7alpha-hydroxylase selective for 24-hydroxycholesterol.

P41004	SMC4_SCHPO	Structural maintenance of chromosomes protein 4	7957061	Fission yeast cut3 and cut14, members of a ubiquitous protein family, are required for chromosome condensation and segregation in mitosis.

P39526	LAA1_YEAST	AP-1 accessory protein LAA1	16687571	Laa1p, a conserved AP-1 accessory protein important for AP-1 localization in yeast.

P29590	PML_HUMAN	Probable transcription factor PML	14976184	Myeloid Elf-1-like factor, an ETS transcription factor, up-regulates lysozyme transcription in epithelial cells through interaction with promyelocytic leukemia protein.

P07204	TRBM_HUMAN	Thrombomodulin	2822087	Human thrombomodulin: complete cDNA sequence and chromosome localization of the gene.

Q9QXJ1	APBB1_MOUSE	Amyloid beta A4 precursor protein-binding family B member 1	8894693	cDNA cloning and chromosome mapping of the human Fe65 gene: interaction of the conserved cytoplasmic domains of the human beta- amyloid precursor protein and its homologues with the mouse Fe65 protein.

Q9UKT5	FBX4_HUMAN	F-box only protein 4	10531035	Identification of a family of human F-box proteins.

Q08749	TIM18_YEAST	Mitochondrial import inner membrane translocase subunit TIM18	10637294	Tim18p is a new component of the Tim54p-Tim22p translocon in the mitochondrial inner membrane.

Q14833	GRM4_HUMAN	Metabotropic glutamate receptor 4	9473604	Group III human metabotropic glutamate receptors 4, 7 and 8: molecular cloning, functional expression, and comparison of pharmacological properties in RGT cells.

Q9H2A9	CHST8_HUMAN	Carbohydrate sulfotransferase 8	11445554	Molecular cloning and expression of two distinct human N- acetylgalactosamine 4-O-sulfotransferases that transfer sulfate to GalNAc beta 1->4GlcNAc beta 1->R in both N- and O-glycans.

Q01883	RAG1_ORYSJ	Seed allergenic protein RAG1	7678765	Gene structure and expression of rice seed allergenic proteins belonging to the alpha-amylase/trypsin inhibitor family.

P25110	ACHD_RAT	Acetylcholine receptor subunit delta	1702709	Primary structure and functional expression of the alpha-, beta-, gamma-, delta- and epsilon-subunits of the acetylcholine receptor from rat muscle.

Q9GZX5	ZN350_HUMAN	Zinc finger protein 350	11090615	Sequence-specific transcriptional corepressor function for BRCA1 through a novel zinc finger protein, ZBRK1.

O54735	PDE5A_RAT	cGMP-specific 3',5'-cyclic phosphodiesterase	9370351	Expression of rat cGMP-binding cGMP-specific phosphodiesterase mRNA in Purkinje cell layers during postnatal neuronal development.

Q99638	RAD9A_HUMAN	Cell cycle checkpoint control protein RAD9A	10359610	The human G2 checkpoint control protein hRAD9 is a nuclear phosphoprotein that forms complexes with hRAD1 and hHUS1.

O95970	LGI1_HUMAN	Leucine-rich glioma-inactivated protein 1	9879993	A novel gene, LGI1, from 10q24 is rearranged and downregulated in malignant brain tumors.

O60907	TBL1X_HUMAN	F-box-like/WD repeat-containing protein TBL1X	11931768	The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2.

P87233	PHF1_SCHPO	SWM histone demethylase complex subunit phf1	17434129	S. pombe LSD1 homologs regulate heterochromatin propagation and euchromatic gene transcription.

Q7T2V2	ST1S3_DANRE	Cytosolic sulfotransferase 3	12745256	cDNA cloning, expression, and functional characterization of a zebrafish SULT1 cytosolic sulfotransferase.

Q09843	RFC2_SCHPO	Replication factor C subunit 2	9862966	A key role for replication factor C in DNA replication checkpoint function in fission yeast.

P40068	FLO8_YEAST	Transcriptional activator FLO8	8913742	Saccharomyces cerevisiae S288C has a mutation in FLO8, a gene required for filamentous growth.

P0A9C3	GALM_ECOLI	Aldose 1-epimerase	7966338	Dependence of lactose metabolism upon mutarotase encoded in the gal operon in Escherichia coli.

Q91YE5	BAZ2A_MOUSE	Bromodomain adjacent to zinc finger domain protein 2A	16085498	The PHD finger/bromodomain of NoRC interacts with acetylated histone H4K16 and is sufficient for rDNA silencing.

Q9LW31	FUS3_ARATH	B3 domain-containing transcription factor FUS3	15363412	The transcription factor FUSCA3 controls developmental timing in Arabidopsis through the hormones gibberellin and abscisic acid.

P40318	DOA10_YEAST	ERAD-associated E3 ubiquitin-protein ligase DOA10	16179953	Ubx2 links the Cdc48 complex to ER-associated protein degradation.

P08218	CEL2B_HUMAN	Chymotrypsin-like elastase family member 2B	3646943	Characterization of pancreatic elastase II cDNAs: two elastase II mRNAs are expressed in human pancreas.

P53080	EDC1_YEAST	Enhancer of mRNA-decapping protein 1	12554867	The enhancer of decapping proteins, Edc1p and Edc2p, bind RNA and stimulate the activity of the decapping enzyme.

Q63563	ABCC9_RAT	ATP-binding cassette sub-family C member 9	8630239	A family of sulfonylurea receptors determines the pharmacological properties of ATP-sensitive K+ channels.

O75570	RF1M_HUMAN	Peptide chain release factor 1, mitochondrial	9838146	Identification and cloning of human mitochondrial translational release factor 1 and the ribosome recycling factor.

P47928	ID4_HUMAN	DNA-binding protein inhibitor ID-4	7665172	Molecular cloning of ID4, a novel dominant negative helix-loop-helix human gene on chromosome 6p21.3-p22.

Q0ZLH2	PJVK_MOUSE	Pejvakin	16804542	Mutations in the gene encoding pejvakin, a newly identified protein of the afferent auditory pathway, cause DFNB59 auditory neuropathy.

Q06608	PDXH_YEAST	Pyridoxamine 5'-phosphate oxidase homolog	14562095	Global analysis of protein localization in budding yeast.

Q2V3I3	EPFL4_ARATH	EPIDERMAL PATTERNING FACTOR-like protein 4	19435754	Epidermal cell density is autoregulated via a secretory peptide, EPIDERMAL PATTERNING FACTOR 2 in Arabidopsis leaves.

Q04341	MIC14_YEAST	Mitochondrial intermembrane space cysteine motif-containing protein MIC14	14562095	Global analysis of protein localization in budding yeast.

O43918	AIRE_HUMAN	Autoimmune regulator	9398839	Positional cloning of the APECED gene.

Q9M7Q4	AI5L5_ARATH	ABSCISIC ACID-INSENSITIVE 5-like protein 5	11005831	Arabidopsis basic leucine zipper transcription factors involved in an abscisic acid-dependent signal transduction pathway under drought and high-salinity conditions.

Q8N163	K1967_HUMAN	Protein KIAA1967	19218236	Inhibition of SUV39H1 methyltransferase activity by DBC1.

O42971	APC10_SCHPO	Anaphase-promoting complex subunit 10	9736616	Apc10 and Ste9/Srw1, two regulators of the APC-cyclosome, as well as the CDK inhibitor Rum1 are required for G1 cell-cycle arrest in fission yeast.

Q9Y662	HS3SB_HUMAN	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1	9988767	Multiple isoforms of heparan sulfate D-glucosaminyl 3-O- sulfotransferase. Isolation, characterization, and expression of human cDNAs and identification of distinct genomic loci.

Q9S834	CLPP5_ARATH	ATP-dependent Clp protease proteolytic subunit 5, chloroplastic	14593120	Clp protease complexes from photosynthetic and non-photosynthetic plastids and mitochondria of plants, their predicted three-dimensional structures, and functional implications.

Q9UQ84	EXO1_HUMAN	Exonuclease 1	12414623	Functional alterations of human exonuclease 1 mutants identified in atypical hereditary nonpolyposis colorectal cancer syndrome.

O95201	ZN205_HUMAN	Zinc finger protein 205	9787081	Identification of two Kruppel-related zinc finger genes (ZNF200 and ZNF210) from human chromosome 16p13.3.

Q9UT67	YQA4_SCHPO	Uncharacterized glycosyltransferase C4F11.04c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q91XA9	CHIA_MOUSE	Acidic mammalian chitinase	18824549	Acidic mammalian chitinase is secreted via an ADAM17/epidermal growth factor receptor-dependent pathway and stimulates chemokine production by pulmonary epithelial cells.

Q08474	VAM10_YEAST	Vacuolar morphogenesis protein 10	12748377	Vam10p defines a Sec18p-independent step of priming that allows yeast vacuole tethering.

P75905	PGAC_ECOLI	Poly-beta-1,6-N-acetyl-D-glucosamine synthase	15090514	The pgaABCD locus of Escherichia coli promotes the synthesis of a polysaccharide adhesin required for biofilm formation.

Q86TG7	PEG10_HUMAN	Retrotransposon-derived protein PEG10	15611116	Human retroviral gag- and gag-pol-like proteins interact with the transforming growth factor-beta receptor activin receptor-like kinase 1.

Q9P7X5	PPK32_SCHPO	Protein kinase domain-containing protein ppk32	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NXA8	SIRT5_HUMAN	NAD-dependent deacetylase sirtuin-5	10381378	Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity.

O14040	DIS3L_SCHPO	Dis3-like exonuclease C2C4.07c	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

P30307	MPIP3_HUMAN	M-phase inducer phosphatase 3	2195549	Human homolog of fission yeast cdc25 mitotic inducer is predominantly expressed in G2.

Q8JZL0	ZN467_MOUSE	Zinc finger protein 467	12426389	A novel nuclear zinc finger protein EZI enhances nuclear retention and transactivation of STAT3.

P25818	TIP11_ARATH	Aquaporin TIP1-1	8508761	The vacuolar membrane protein gamma-TIP creates water specific channels in Xenopus oocytes.

O95376	ARI2_HUMAN	E3 ubiquitin-protein ligase ARIH2	10422847	TRIADs: a new class of proteins with a novel cysteine-rich signature.

Q9EQ25	S38A4_RAT	Sodium-coupled neutral amino acid transporter 4	11118514	Structure and function of ATA3, a new subtype of amino acid transport system A, primarily expressed in the liver and skeletal muscle.

Q12471	6P22_YEAST	6-phosphofructo-2-kinase 2	8861205	Cloning of a second gene encoding 5-phosphofructo-2-kinase in yeast, and characterization of mutant strains without fructose-2,6- bisphosphate.

P08640	MUC1_YEAST	Flocculation protein FLO11	8710886	Muc1, a mucin-like protein that is regulated by Mss10, is critical for pseudohyphal differentiation in yeast.

Q9R1K2	TEN2_RAT	Teneurin-2	10419693	Neurestin: putative transmembrane molecule implicated in neuronal development.

P84245	H33_RAT	Histone H3.3	7877725	H1(0) and H3.3B mRNA levels in developing rat brain.

Q9Y169	EXT2_DROME	Exostosin-2	14998928	Distinct and collaborative roles of Drosophila EXT family proteins in morphogen signalling and gradient formation.

P41695	BUB1_YEAST	Checkpoint serine/threonine-protein kinase BUB1	7969164	The Saccharomyces cerevisiae checkpoint gene BUB1 encodes a novel protein kinase.

P09237	MMP7_HUMAN	Matrilysin	1497627	Molecular characterization of a low-molecular-mass matrix metalloproteinase secreted by glomerular mesangial cells as PUMP-1.

P47008	SFH5_YEAST	Phosphatidylinositol transfer protein SFH5	12869188	Subcellular localization of yeast Sec14 homologues and their involvement in regulation of phospholipid turnover.

P55863	SOX3A_XENLA	Transcription factor Sox-3-A	9328277	Isolation and Characterization of Xenopus laevis xSox-B1 cDNA.

P05198	IF2A_HUMAN	Eukaryotic translation initiation factor 2 subunit 1	2948954	Cloning and sequencing of complementary DNAs encoding the alpha- subunit of translational initiation factor eIF-2. Characterization of the protein and its messenger RNA.

Q9VVR1	NOT_DROME	Ubiquitin carboxyl-terminal hydrolase nonstop	18206972	A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing.

Q9UBP0	SPAST_HUMAN	Spastin	19000169	Spastin couples microtubule severing to membrane traffic in completion of cytokinesis and secretion.

Q9GZM7	TINAL_HUMAN	Tubulointerstitial nephritis antigen-like	10799322	Cloning, characterization, and expression of the human TIN-ag-RP gene encoding a novel putative extracellular matrix protein.

Q8WTS1	ABHD5_HUMAN	1-acylglycerol-3-phosphate O-acyltransferase ABHD5	16679289	Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome.

P81299	CDC14_CAEEL	Probable tyrosine-protein phosphatase cdc-14	12213836	The CeCDC-14 phosphatase is required for cytokinesis in the Caenorhabditis elegans embryo.

P48681	NEST_HUMAN	Nestin	9917366	Heterogeneity of neural progenitor cells revealed by enhancers in the nestin gene.

Q92317	NCB2_YEAST	Negative cofactor 2 complex subunit beta	12237409	Direct stimulation of transcription by negative cofactor 2 (NC2) through TATA-binding protein (TBP).

O94494	SIM4_SCHPO	Centromere protein sim4	12719471	Sim4: a novel fission yeast kinetochore protein required for centromeric silencing and chromosome segregation.

Q13201	MMRN1_HUMAN	Multimerin-1	8514871	Multimerin is found in the alpha-granules of resting platelets and is synthesized by a megakaryocytic cell line.

P36608	NCS1_CAEEL	Neuronal calcium sensor 1	11343658	Calcium-signalling via the neuron calcium sensor-1 regulates associative learning and memory in C.elegans.

Q9WUD1	CHIP_MOUSE	STIP1 homology and U box-containing protein 1	16307917	Chaperoned ubiquitylation -- crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex.

P43557	FMP32_YEAST	Protein FMP32, mitochondrial	12514182	Bipartite signals mediate subcellular targeting of tail-anchored membrane proteins in Saccharomyces cerevisiae.

Q8NI17	IL31R_HUMAN	Interleukin-31 receptor subunit alpha	11877449	A novel type I cytokine receptor is expressed on monocytes, signals proliferation, and activates STAT-3 and STAT-5.

Q6VY05	DND1_MOUSE	Dead end protein homolog 1	18509452	Mouse apolipoprotein B editing complex 3 (APOBEC3) is expressed in germ cells and interacts with dead-end (DND1).

P38814	SBE22_YEAST	Protein SBE22	14562095	Global analysis of protein localization in budding yeast.

P32566	SMI1_YEAST	Cell wall assembly regulator SMI1	10206705	KNR4, a suppressor of Saccharomyces cerevisiae cwh mutants, is involved in the transcriptional control of chitin synthase genes.

P81911	OR22C_DROME	Putative odorant receptor 22c	10069338	A novel family of divergent seven-transmembrane proteins: candidate odorant receptors in Drosophila.

Q9SRX3	GUN1_ARATH	Endoglucanase 1	10074717	Identification of genes expressed during early Arabidopsis carpel development by mRNA differential display: characterisation of ATCEL2, a novel endo-1,4-beta-D-glucanase gene.

P70281	SYCP3_MOUSE	Synaptonemal complex protein 3	10678170	The murine SCP3 gene is required for synaptonemal complex assembly, chromosome synapsis, and male fertility.

P46937	YAP1_HUMAN	Yorkie homolog	18158288	Tumor suppressor LATS1 is a negative regulator of oncogene YAP.

P20292	AL5AP_HUMAN	Arachidonate 5-lipoxygenase-activating protein	19233132	Distinct parts of leukotriene C(4) synthase interact with 5- lipoxygenase and 5-lipoxygenase activating protein.

P35611	ADDA_HUMAN	Alpha-adducin	1840603	Primary structure and domain organization of human alpha and beta adducin.

Q9V576	WUN_DROME	Putative phosphatidate phosphatase	8985246	The Drosophila protein Wunen repels migrating germ cells.

P53129	MON1_YEAST	Vacuolar fusion protein MON1	14662743	Yeast homotypic vacuole fusion requires the Ccz1-Mon1 complex during the tethering/docking stage.

Q9S7U9	M2K2_ARATH	Mitogen-activated protein kinase kinase 2	9878570	Isolation of ATMEKK1 (a MAP kinase kinase kinase)-interacting proteins and analysis of a MAP kinase cascade in Arabidopsis.

Q9FLP5	SUMO3_ARATH	Small ubiquitin-related modifier 3	12482876	The small ubiquitin-like modifier (SUMO) protein modification system in Arabidopsis. Accumulation of SUMO1 and -2 conjugates is increased by stress.

P49897	IOD3_RAT	Type III iodothyronine deiodinase	7622463	Cloning and expression of a cDNA for a mammalian type III iodothyronine deiodinase.

Q9NRD5	PICK1_HUMAN	PRKCA-binding protein	11343649	Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1.

Q8IUH4	ZDH13_HUMAN	Palmitoyltransferase ZDHHC13	12761501	Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.

Q9VYS4	GLD2B_DROME	Poly(A) RNA polymerase gld-2 homolog B	10747060	The Drosophila wispy gene is required for RNA localization and other microtubule-based events of meiosis and early embryogenesis.

O16850	FOXO_CAEEL	Forkhead box protein O	11381260	Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling.

P49773	HINT1_HUMAN	Histidine triad nucleotide-binding protein 1	8812426	Cloning, mapping, and in vivo localization of a human member of the PKCI-1 protein family (PRKCNH1).

Q64535	ATP7B_RAT	Copper-transporting ATPase 2	9920665	A novel pineal night-specific ATPase encoded by the Wilson disease gene.

P69054	DHSC_ECOLI	Succinate dehydrogenase cytochrome b556 subunit	9822661	The quinone-binding site in succinate-ubiquinone reductase from Escherichia coli. Quinone-binding domain and amino acid residues involved in quinone binding.

P25651	CSM1_YEAST	Monopolin complex subunit CSM1	15023545	Saccharomyces cerevisiae CSM1 gene encoding a protein influencing chromosome segregation in meiosis I interacts with elements of the DNA replication complex.

Q9Z0P7	SUFU_MOUSE	Suppressor of fused homolog	11252182	Suppressor of fused gene involved in hedgehog signal transduction in Drosophila melanogaster is conserved in mammals.

P59910	DJB13_HUMAN	DnaJ homolog subfamily B member 13	12673577	Molecular cloning of TSARG3 gene related to apoptosis in human spermatogenic cells.

Q13616	CUL1_HUMAN	Cullin-1	12609982	TIP120A associates with cullins and modulates ubiquitin ligase activity.

Q9BZW2	S13A1_HUMAN	Solute carrier family 13 member 1	11161786	The human renal sodium sulfate cotransporter (SLC13A1; hNaSi-1) cDNA and gene: organization, chromosomal localization, and functional characterization.

Q02207	FOX2_YEAST	Peroxisomal hydratase-dehydrogenase-epimerase	1551874	Peroxisomal multifunctional beta-oxidation protein of Saccharomyces cerevisiae. Molecular analysis of the fox2 gene and gene product.

Q4V7C7	ARP3_RAT	Actin-related protein 3	18064521	Actin-related protein 3 (Arp3) is mutated in proteinuric BUF/Mna rats.

Q05543	RT103_YEAST	Regulator of Ty1 transposition protein 103	11779788	Multiple regulators of Ty1 transposition in Saccharomyces cerevisiae have conserved roles in genome maintenance.

P15891	ABP1_YEAST	Actin-binding protein	11668184	Unusual binding properties of the SH3 domain of the yeast actin- binding protein Abp1: structural and functional analysis.

Q9JIX5	CHD8_RAT	Chromodomain-helicase-DNA-binding protein 8	11744694	Nuclear localization of Duplin, a beta-catenin-binding protein, is essential for its inhibitory activity on the Wnt signaling pathway.

Q7KSD8	TAD2A_DROME	Transcriptional adapter 2A	12697829	Two Drosophila Ada2 homologues function in different multiprotein complexes.

O14229	SFC1_SCHPO	Transcription factor tau subunit sfc1	16751097	A role for TFIIIC transcription factor complex in genome organization.

O15400	STX7_HUMAN	Syntaxin-7	9358037	Human syntaxin 7: a Pep12p/Vps6p homologue implicated in vesicle trafficking to lysosomes.

Q13216	ERCC8_HUMAN	DNA excision repair protein ERCC-8	16751180	CSA-dependent degradation of CSB by the ubiquitin-proteasome pathway establishes a link between complementation factors of the Cockayne syndrome.

Q8TAD4	ZNT5_HUMAN	Zinc transporter 5	11937503	A novel zinc-regulated human zinc transporter, hZTL1, is localized to the enterocyte apical membrane.

P11117	PPAL_HUMAN	Lysosomal acid phosphatase	3191910	Human lysosomal acid phosphatase: cloning, expression and chromosomal assignment.

O17468	HIRA_DROME	Protein HIRA homolog	11735001	The Drosophila maternal gene sesame is required for sperm chromatin remodeling at fertilization.

Q8N122	RPTOR_HUMAN	Regulatory-associated protein of mTOR	17386266	PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase.

Q00987	MDM2_HUMAN	E3 ubiquitin-protein ligase Mdm2	8875929	Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain.

O55193	CCR2_RAT	C-C chemokine receptor type 2	9655467	Chemokine receptor expression in cultured glia and rat experimental allergic encephalomyelitis.

P38146	YPT10_YEAST	GTP-binding protein YPT10	11785952	Saccharomyces cerevisiae Pra1p/Yip3p interacts with Yip1p and Rab proteins.

P22413	ENPP1_HUMAN	Ectonucleotide pyrophosphatase/phosphodiesterase family member 1	8001561	Biochemical characterization of human PC-1, an enzyme possessing alkaline phosphodiesterase I and nucleotide pyrophosphatase activities.

P53073	EMC4_YEAST	ER membrane protein complex subunit 4	19325107	Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum.

Q9SYN1	PEN6_ARATH	Pentacyclic triterpene synthase 6	11247608	Molecular cloning and expression in yeast of 2,3-oxidosqualene- triterpenoid cyclases from Arabidopsis thaliana.

O60936	NOL3_HUMAN	Nucleolar protein 3	10196175	Alternative splicing determines the intracellular localization of the novel nuclear protein Nop30 and its interaction with the splicing factor SRp30c.

P31539	HS104_YEAST	Heat shock protein 104	9674429	Hsp104, Hsp70, and Hsp40: a novel chaperone system that rescues previously aggregated proteins.

Q03631	WAR1_YEAST	Weak acid resistance protein 1	12588995	War1p, a novel transcription factor controlling weak acid stress response in yeast.

P53923	CTU2_YEAST	Cytoplasmic tRNA 2-thiolation protein 2	14551258	Urmylation: a ubiquitin-like pathway that functions during invasive growth and budding in yeast.

Q05789	YL211_YEAST	Uncharacterized protein YLR211C	14562095	Global analysis of protein localization in budding yeast.

Q9FGM1	PYL8_ARATH	Abscisic acid receptor PYL8	19874541	PYR/PYL/RCAR family members are major in-vivo ABI1 protein phosphatase 2C-interacting proteins in Arabidopsis.

P14618	KPYM_HUMAN	Pyruvate kinase isozymes M1/M2	2040271	Isolation and characterization of the human pyruvate kinase M gene.

Q9P2J3	KLHL9_HUMAN	Kelch-like protein 9	17543862	A Cul3-based E3 ligase removes Aurora B from mitotic chromosomes, regulating mitotic progression and completion of cytokinesis in human cells.

P25724	NANOS_DROME	Protein nanos	11700288	Translational regulation and RNA localization in Drosophila oocytes and embryos.

P53187	HOP2_YEAST	Homologous-pairing protein 2	9708739	The meiosis-specific Hop2 protein of S. cerevisiae ensures synapsis between homologous chromosomes.

Q9LNT9	ASK4_ARATH	SKP1-like protein 4	12970487	Members of the Arabidopsis-SKP1-like gene family exhibit a variety of expression patterns and may play diverse roles in Arabidopsis.

Q05466	HAT4_ARATH	Homeobox-leucine zipper protein HAT4	8253077	The Athb-1 and -2 HD-Zip domains homodimerize forming complexes of different DNA binding specificities.

P92973	CCA1_ARATH	Protein CCA1	9144958	A Myb-related transcription factor is involved in the phytochrome regulation of an Arabidopsis Lhcb gene.

Q9UBM7	DHCR7_HUMAN	7-dehydrocholesterol reductase	9878250	The human lamin B receptor/sterol reductase multigene family.

Q9URV2	APC1_SCHPO	Anaphase-promoting complex subunit 1	8918880	20S cyclosome complex formation and proteolytic activity inhibited by the cAMP/PKA pathway.

P35922	FMR1_MOUSE	Fragile X mental retardation protein 1 homolog	11438699	A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P.

Q9SH59	RTNLC_ARATH	Reticulon-like protein B3	16618929	Mapping the Arabidopsis organelle proteome.

Q9CYH5	GFOD2_MOUSE	Glucose-fructose oxidoreductase domain-containing protein 2	18757743	Transcriptome-based systematic identification of extracellular matrix proteins.

Q9Y6R1	S4A4_HUMAN	Electrogenic sodium bicarbonate cotransporter 1	9651366	Molecular cloning, chromosomal localization, tissue distribution, and functional expression of the human pancreatic sodium bicarbonate cotransporter.

Q696W0	SPEG_DANRE	Striated muscle preferentially expressed protein kinase	15185077	Orthologous relationship of obscurin and Unc-89: phylogeny of a novel family of tandem myosin light chain kinases.

P24522	GA45A_HUMAN	Growth arrest and DNA damage-inducible protein GADD45 alpha	7973727	Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen.

Q00764	TPS1_YEAST	Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit	9837904	Composition and functional analysis of the Saccharomyces cerevisiae trehalose synthase complex.

Q02972	CADH8_ARATH	Cinnamyl alcohol dehydrogenase 8	1464303	Rapid activation of a novel plant defense gene is strictly dependent on the Arabidopsis RPM1 disease resistance locus.

P32085	TBP_CAEEL	TATA-box-binding protein	8415761	Cloning and properties of the Caenorhabditis elegans TATA-box-binding protein.

Q9XF91	PSBS_ARATH	Photosystem II 22 kDa protein, chloroplastic	10667783	A pigment-binding protein essential for regulation of photosynthetic light harvesting.

Q06945	SOX4_HUMAN	Transcription factor SOX-4	16631117	Ubc9 interacts with SOX4 and represses its transcriptional activity.

Q9R066	CXAR_RAT	Coxsackievirus and adenovirus receptor homolog	10490761	Expression of Coxsackie-adenovirus-receptor and alpha v-integrin does not correlate with adenovector targeting in vivo indicating anatomical vector barriers.

B7ZS96	TTHY_XENLA	Transthyretin	11017780	Effect of diethylstilbestrol on thyroid hormone binding to amphibian transthyretins.

O15379	HDAC3_HUMAN	Histone deacetylase 3	12628926	Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1.

Q945S5	CAX4_ARATH	Vacuolar cation/proton exchanger 4	11950973	Characterization of CAX4, an Arabidopsis H(+)/cation antiporter.

B6F1W5	KTU_ORYLA	Protein kintoun	19052621	Ktu/PF13 is required for cytoplasmic pre-assembly of axonemal dyneins.

Q9Y242	TCF19_HUMAN	Transcription factor 19	1868030	A new growth-regulated complementary DNA with the sequence of a putative trans-activating factor.

Q9VNB5	OR83B_DROME	Odorant receptor 83b	16402857	Atypical membrane topology and heteromeric function of Drosophila odorant receptors in vivo.

Q9ULD8	KCNH3_HUMAN	Potassium voltage-gated channel subfamily H member 3	10455180	New ether-a-go-go K+ channel family members localized in human telencephalon.

Q13444	ADA15_HUMAN	Disintegrin and metalloproteinase domain-containing protein 15	9516430	Specific interaction of the recombinant disintegrin-like domain of MDC-15 (metargidin, ADAM-15) with integrin alphavbeta3.

Q8TEY7	UBP33_HUMAN	Ubiquitin carboxyl-terminal hydrolase 33	11739384	Ubiquitination of a novel deubiquitinating enzyme requires direct binding to von Hippel-Lindau tumor suppressor protein.

Q8NF91	SYNE1_HUMAN	Nesprin-1	11792814	Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.

O74509	VAM7_SCHPO	Vacuolar morphogenesis protein 7 homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P32288	GLNA_YEAST	Glutamine synthetase	1347768	Sequence of the GLN1 gene of Saccharomyces cerevisiae: role of the upstream region in regulation of glutamine synthetase expression.

P39987	HSP7E_YEAST	Heat shock protein SSC3, mitochondrial	12943685	Ecm10p localizes in yeast mitochondrial nucleoids and its overexpression induces extensive mitochondrial DNA aggregations.

Q9UPA5	BSN_HUMAN	Protein bassoon	9806829	Cloning and mapping of ZNF231, a novel brain-specific gene encoding neuronal double zinc finger protein whose expression is enhanced in a neurodegenerative disorder, multiple system atrophy.

P04075	ALDOA_HUMAN	Fructose-bisphosphate aldolase A	14615364	Hemolytic anemia and severe rhabdomyolysis caused by compound heterozygous mutations of the gene for erythrocyte/muscle isozyme of aldolase, ALDOA(Arg303X/Cys338Tyr).

Q681I0	ORTHL_ARATH	E3 ubiquitin-protein ligase ORTHRUS-LIKE 1	18643997	ORTH/VIM proteins that regulate DNA methylation are functional ubiquitin E3 ligases.

P53968	CRZ1_YEAST	Transcriptional regulator CRZ1	10197980	Yeast calcineurin regulates nuclear localization of the Crz1p transcription factor through dephosphorylation.

P14404	EVI1_MOUSE	MDS1 and EVI1 complex locus protein EVI1	2106070	Identification, nuclear localization, and DNA-binding activity of the zinc finger protein encoded by the Evi-1 myeloid transforming gene.

Q12473	FRE6_YEAST	Ferric reductase transmembrane component 6	14562095	Global analysis of protein localization in budding yeast.

P33399	LAH1_YEAST	La protein homolog	7799435	A yeast RNA binding protein that resembles the human autoantigen La.

Q14831	GRM7_HUMAN	Metabotropic glutamate receptor 7	9473604	Group III human metabotropic glutamate receptors 4, 7 and 8: molecular cloning, functional expression, and comparison of pharmacological properties in RGT cells.

Q8K3V4	PADI6_MOUSE	Protein-arginine deiminase type-6	12654293	ePAD, an oocyte and early embryo-abundant peptidylarginine deiminase- like protein that localizes to egg cytoplasmic sheets.

Q02413	DSG1_HUMAN	Desmoglein-1	1711210	Desmosomal glycoprotein DGI, a component of intercellular desmosome junctions, is related to the cadherin family of cell adhesion molecules.

Q99836	MYD88_HUMAN	Myeloid differentiation primary response protein MyD88	9013863	The cloning and characterization of human MyD88: a member of an IL-1 receptor related family.

P38835	YHT1_YEAST	PH domain-containing protein YHR131C	14562095	Global analysis of protein localization in budding yeast.

Q02795	OSTD_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit SWP1	15831493	Subunits of the translocon interact with components of the oligosaccharyl transferase complex.

P85528	KAX6F_HEMLE	Potassium channel toxin alpha-KTx 6.15	18699777	Hemitoxin, the first potassium channel toxin from the venom of the Iranian scorpion Hemiscorpius lepturus.

Q9JI83	PLAC1_MOUSE	Placenta-specific protein 1	10995572	PLAC1, an Xq26 gene with placenta-specific expression.

P47136	BUD4_YEAST	Bud site selection protein 4	12446742	Iqg1p links spatial and secretion landmarks to polarity and cytokinesis.

P03372	ESR1_HUMAN	Estrogen receptor	17006958	MS-KIF18A, a kinesin, is associated with estrogen receptor.

Q18807	ODR10_CAEEL	Serpentine receptor class r-10	8601313	odr-10 encodes a seven transmembrane domain olfactory receptor required for responses to the odorant diacetyl.

Q15172	2A5A_HUMAN	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform	8703017	The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm.

Q9FH36	GAUTC_ARATH	Probable galacturonosyltransferase 12	17322407	Arabidopsis irregular xylem8 and irregular xylem9: implications for the complexity of glucuronoxylan biosynthesis.

P20241	NRG_DROME	Neuroglian	15459097	Drosophila contactin, a homolog of vertebrate contactin, is required for septate junction organization and paracellular barrier function.

P35285	RB22A_MOUSE	Ras-related protein Rab-22A	16034420	Structural basis of family-wide Rab GTPase recognition by rabenosyn- 5.

Q9FL28	FLS2_ARATH	LRR receptor-like serine/threonine-protein kinase FLS2	11564731	Sensitivity of different ecotypes and mutants of Arabidopsis thaliana toward the bacterial elicitor flagellin correlates with the presence of receptor-binding sites.

P39727	ERV46_YEAST	ER-derived vesicles protein ERV46	11157978	Erv41p and Erv46p: new components of COPII vesicles involved in transport between the ER and Golgi complex.

Q5AVZ7	EXGD_EMENI	Glucan 1,3-beta-glucosidase D	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

Q8ZQ59	PIPB_SALTY	Secreted effector protein pipB	11918798	Salmonella effectors within a single pathogenicity island are differentially expressed and translocated by separate type III secretion systems.

P16649	TUP1_YEAST	General transcriptional corepressor TUP1	11172717	TUP1 utilizes histone H3/H2B-specific HDA1 deacetylase to repress gene activity in yeast.

P26449	BUB3_YEAST	Cell cycle arrest protein BUB3	15879521	Two complexes of spindle checkpoint proteins containing Cdc20 and Mad2 assemble during mitosis independently of the kinetochore in Saccharomyces cerevisiae.

O08969	PHLA2_MOUSE	Pleckstrin homology-like domain family A member 2	12032310	Placental overgrowth in mice lacking the imprinted gene Ipl.

P35270	SPRE_HUMAN	Sepiapterin reductase	1883349	Cloning and sequencing of cDNA encoding human sepiapterin reductase -- an enzyme involved in tetrahydrobiopterin biosynthesis.

P36102	PAN3_YEAST	PAB-dependent poly(A)-specific ribonuclease subunit PAN3	11953437	Posttranscriptional regulation of the RAD5 DNA repair gene by the Dun1 kinase and the Pan2-Pan3 poly(A)-nuclease complex contributes to survival of replication blocks.

P20823	HNF1A_HUMAN	Hepatocyte nuclear factor 1-alpha	10333057	Three new mutations in the hepatocyte nuclear factor-1alpha gene in Japanese subjects with diabetes mellitus: clinical features and functional characterization.

Q9Y7U4	NSE3_SCHPO	Non-structural maintenance of chromosome element 3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9W1U5	GR59C_DROME	Putative gustatory receptor 59c	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

Q05583	CIAO1_YEAST	Cytosolic iron-sulfur protein assembly protein 1	14562095	Global analysis of protein localization in budding yeast.

Q8R2N1	AQP3_MOUSE	Aquaporin-3	17429015	The role of aquaporin 3 in the movement of water and cryoprotectants in mouse morulae.

Q9LZG0	ADK2_ARATH	Adenosine kinase 2	11115893	Adenosine kinase of Arabidopsis. Kinetic properties and gene expression.

Q9HAF1	EAF6_HUMAN	Chromatin modification-related protein MEAF6	16387653	ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.

Q7ZXF3	ID4_XENLA	DNA-binding protein inhibitor ID-4	14651922	Cloning and characterization of Xenopus Id4 reveals differing roles for Id genes.

Q63713	RASA2_RAT	Ras GTPase-activating protein 2	7935405	A novel mammalian Ras GTPase-activating protein which has phospholipid-binding and Btk homology regions.

O70126	AURKB_MOUSE	Serine/threonine-protein kinase 12	8647446	Cell-cycle-dependent expression of the STK-1 gene encoding a novel murine putative protein kinase.

Q9M0S4	AGP10_ARATH	Classical arabinogalactan protein 10	11006345	The classical arabinogalactan protein gene family of Arabidopsis.

Q07551	KAR_YEAST	NADPH-dependent alpha-keto amide reductase	14562095	Global analysis of protein localization in budding yeast.

P50651	RIR2A_ARATH	Ribonucleoside-diphosphate reductase small chain A	16399800	Arabidopsis ribonucleotide reductases are critical for cell cycle progression, DNA damage repair, and plant development.

Q9Y7K6	YGI4_SCHPO	Uncharacterized RING finger protein C2A9.04c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O74818	YBJ7_SCHPO	Uncharacterized carboxypeptidase C337.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P80645	SSUD_ECOLI	Alkanesulfonate monooxygenase	10480865	Characterization of a two-component alkanesulfonate monooxygenase from Escherichia coli.

Q9Y6X3	SCC4_HUMAN	Cohesin loading complex subunit SCC4 homolog	16802858	Metazoan Scc4 homologs link sister chromatid cohesion to cell and axon migration guidance.

Q2VWA4	SKOR2_HUMAN	SKI family transcriptional corepressor 2	16200078	Cloning and functional characterization of a new Ski homolog, Fussel- 18, specifically expressed in neuronal tissues.

Q7TSJ2	MAP6_MOUSE	Microtubule-associated protein 6	16837464	STOP-like protein 21 is a novel member of the STOP family, revealing a Golgi localization of STOP proteins.

P34121	COAA_DICDI	Coactosin	8293475	Coactosin, a 17 kDa F-actin binding protein from Dictyostelium discoideum.

O00622	CYR61_HUMAN	Protein CYR61	9135077	The human growth factor-inducible immediate early gene, CYR61, maps to chromosome 1p.

O04197	COI1_ARATH	Coronatine-insensitive protein 1	9582125	COI1: an Arabidopsis gene required for jasmonate-regulated defense and fertility.

P40231	CSK2A_SCHPO	Casein kinase II subunit alpha	8264625	The Schizosaccharomyces pombe casein kinase II alpha and beta subunits: evolutionary conservation and positive role of the beta subunit.

Q9NRG0	CHRC1_HUMAN	Chromatin accessibility complex protein 1	10880450	HuCHRAC, a human ISWI chromatin remodelling complex contains hACF1 and two novel histone-fold proteins.

P01623	KV305_HUMAN	Ig kappa chain V-III region WOL	6794615	Amino acid sequence of the variable regions of light chains from two idiotypically cross-reactive human IgM anti-gamma-globulins of the Wa group.

P55957	BID_HUMAN	BH3-interacting domain death agonist	8918887	BID: a novel BH3 domain-only death agonist.

Q64321	ZBT7B_MOUSE	Zinc finger and BTB domain-containing protein 7B	7937772	c-Krox, a transcriptional regulator of type I collagen gene expression, is preferentially expressed in skin.

Q9BRG2	SH23A_HUMAN	SH2 domain-containing protein 3A	10187783	NSP1 defines a novel family of adaptor proteins linking integrin and tyrosine kinase receptors to the c-Jun N-terminal kinase/stress- activated protein kinase signaling pathway.

P43273	TGA2_ARATH	Transcription factor TGA2	8628224	Binding specificity and tissue-specific expression pattern of the Arabidopsis bZIP transcription factor TGA2.

Q9Z1P8	ANGL4_MOUSE	Angiopoietin-related protein 4	10698685	Hepatic expression, synthesis and secretion of a novel fibrinogen/angiopoietin-related protein that prevents endothelial-cell apoptosis.

P09626	ATP4A_RAT	Potassium-transporting ATPase alpha chain 1	3023364	Molecular cloning of the rat stomach (H+ + K+)-ATPase.

P48740	MASP1_HUMAN	Mannan-binding lectin serine protease 1	11527969	Substrate specificities of recombinant mannan-binding lectin- associated serine proteases-1 and -2.

Q8IHS4	CCD1_PLAF7	Coiled-coil domain-containing protein PF11_0455	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

Q922Y0	DYRK3_MOUSE	Dual specificity tyrosine-phosphorylation-regulated kinase 3	16524748	Erythropoietin-dependent erythropoiesis: new insights and questions.

Q08581	SLK19_YEAST	Kinetochore protein SLK19	11533655	Orchestrating anaphase and mitotic exit: separase cleavage and localization of Slk19.

Q03145	EPHA2_MOUSE	Ephrin type-A receptor 2	16782872	Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis.

P32898	CYM1_YEAST	Mitochondrial presequence protease	15606766	Enhanced peptide secretion by gene disruption of CYM1, a novel protease in Saccharomyces cerevisiae.

P49010	HEXC_BOMMO	Chitooligosaccharidolytic beta-N-acetylglucosaminidase	7766021	Purification of a chitooligosaccharidolytic beta-N- acetylglucosaminidase from Bombyx mori larvae during metamorphosis and the nucleotide sequence of its cDNA.

O60507	TPST1_HUMAN	Protein-tyrosine sulfotransferase 1	9501187	Tyrosylprotein sulfotransferase: purification and molecular cloning of an enzyme that catalyzes tyrosine O-sulfation, a common posttranslational modification of eukaryotic proteins.

P04689	TBA2_SCHPO	Tubulin alpha-2 chain	6327053	Identification of the pleiotropic cell division cycle gene NDA2 as one of two different alpha-tubulin genes in Schizosaccharomyces pombe.

P34208	CHK1_SCHPO	Serine/threonine-protein kinase chk1	9278510	Cdc25 mitotic inducer targeted by chk1 DNA damage checkpoint kinase.

Q9HCS7	SYF1_HUMAN	Pre-mRNA-splicing factor SYF1	10944529	XAB2, a novel tetratricopeptide repeat protein, involved in transcription-coupled DNA repair and transcription.

P20350	RHOM_DROME	Protein rhomboid	11672525	Drosophila Rhomboid-1 defines a family of putative intramembrane serine proteases.

Q9HE07	YK96_SCHPO	Uncharacterized protein C20H4.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8TDX5	ACMSD_HUMAN	2-amino-3-carboxymuconate-6-semialdehyde decarboxylase	12140278	Identification and expression of a cDNA encoding human alpha-amino- beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD). A key enzyme for the tryptophan-niacine pathway and 'quinolinate hypothesis'.

P14735	IDE_HUMAN	Insulin-degrading enzyme	3059494	Human insulin-degrading enzyme shares structural and functional homologies with E. coli protease III.

P32843	YME2_YEAST	Mitochondrial escape protein 2	8514129	Nuclear mutations in Saccharomyces cerevisiae that affect the escape of DNA from mitochondria to the nucleus.

Q01080	RPA49_YEAST	DNA-directed RNA polymerase I subunit RPA49	1409638	Characterization and mutagenesis of the gene encoding the A49 subunit of RNA polymerase A in Saccharomyces cerevisiae.

Q96AP0	ACD_HUMAN	Adrenocortical dysplasia protein homolog	16166375	Shelterin: the protein complex that shapes and safeguards human telomeres.

P46962	CTK2_YEAST	CTD kinase subunit beta	11118453	Activation of the cyclin-dependent kinase CTDK-I requires the heterodimerization of two unstable subunits.

Q9BUL8	PDC10_HUMAN	Programmed cell death protein 10	17360971	PDCD10 interacts with Ste20-related kinase MST4 to promote cell growth and transformation via modulation of the ERK pathway.

P25809	KCRU_RAT	Creatine kinase U-type, mitochondrial	1859839	Structural characterization and tissue-specific expression of the mRNAs encoding isoenzymes from two rat mitochondrial creatine kinase genes.

Q9UUA1	YJX1_SCHPO	Oxysterol-binding protein homolog C23B6.01c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9H267	VP33B_HUMAN	Vacuolar protein sorting-associated protein 33B	20190753	Mutations in VIPAR cause an arthrogryposis, renal dysfunction and cholestasis syndrome phenotype with defects in epithelial polarization.

O74828	ESF1_SCHPO	Pre-rRNA-processing protein esf1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q02413	DSG1_HUMAN	Desmoglein-1	1770008	Structural analysis and expression of human desmoglein: a cadherin- like component of the desmosome.

Q9XEE2	ANXD2_ARATH	Annexin D2	15368128	Immunolocalization and histochemical evidence for the association of two different Arabidopsis annexins with secretion during early seedling growth and development.

P17629	HPR1_YEAST	THO complex subunit HPR1	11979277	TREX is a conserved complex coupling transcription with messenger RNA export.

Q3U8K7	SV421_MOUSE	Histone-lysine N-methyltransferase SUV420H1	15145825	A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin.

Q93ZG7	RH38_ARATH	DEAD-box ATP-dependent RNA helicase 38	15598798	A DEAD box RNA helicase is essential for mRNA export and important for development and stress responses in Arabidopsis.

Q9NYW1	TA2R9_HUMAN	Taste receptor type 2 member 9	10761934	A novel family of mammalian taste receptors.

P47025	MDV1_YEAST	Mitochondrial division protein 1	11038182	Mdv1p is a WD repeat protein that interacts with the dynamin-related GTPase, Dnm1p, to trigger mitochondrial division.

Q9BRP8	WIBG_HUMAN	Partner of Y14 and mago	19410547	Disassembly of exon junction complexes by PYM.

P25490	TYY1_HUMAN	Transcriptional repressor protein YY1	1946405	Isolation of a candidate repressor/activator, NF-E1 (YY-1, delta), that binds to the immunoglobulin kappa 3' enhancer and the immunoglobulin heavy-chain mu E1 site.

Q967U1	PSME_DICDI	Proteasome activator 28	19411624	Characterization of a REG/PA28 proteasome activator homolog in Dictyostelium discoideum indicates that the ubiquitin- and ATP- independent REGgamma proteasome is an ancient nuclear protease.

Q7Z2E3	APTX_HUMAN	Aprataxin	15044383	Aprataxin, a novel protein that protects against genotoxic stress.

P34808	MEI1_CAEEL	Meiotic spindle formation protein mei-1	12781129	Neddylation and deneddylation of CUL-3 is required to target MEI- 1/katanin for degradation at the meiosis-to-mitosis transition in C. elegans.

Q9LY51	PLCD7_ARATH	Phosphoinositide phospholipase C 7	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q96ED9	HOOK2_HUMAN	Protein Hook homolog 2	18799622	An FTS/Hook/p107(FHIP) complex interacts with and promotes endosomal clustering by the homotypic vacuolar protein sorting complex.

Q96P48	ARAP1_HUMAN	Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1	11804590	ARAP1: a point of convergence for Arf and Rho signaling.

Q8C1T8	CLC2H_MOUSE	C-type lectin domain family 2 member H	11398965	Cloning of Clr, a new family of lectin-like genes localized between mouse Nkrp1a and Cd69.

Q8IUD6	RN135_HUMAN	E3 ubiquitin-protein ligase RNF135	19017631	Riplet/RNF135, a RING finger protein, ubiquitinates RIG-I to promote interferon-beta induction during the early phase of viral infection.

Q06568	NDE1_YEAST	Nuclear distribution protein nudE homolog 1	15965467	NudEL targets dynein to microtubule ends through LIS1.

O14757	CHK1_HUMAN	Serine/threonine-protein kinase Chk1	11836499	BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage.

Q9MA55	ACBP4_ARATH	Acyl-CoA-binding domain-containing protein 4	15604682	ACBP4 and ACBP5, novel Arabidopsis acyl-CoA-binding proteins with kelch motifs that bind oleoyl-CoA.

Q9C004	SPY4_HUMAN	Protein sprouty homolog 4	12027893	Human sprouty 4, a new ras antagonist on 5q31, interacts with the dual specificity kinase TESK1.

Q08209	PP2BA_HUMAN	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	11842093	Calsarcin-3, a novel skeletal muscle-specific member of the calsarcin family, interacts with multiple Z-disc proteins.

P47089	DENR_YEAST	Translation machinery-associated protein 22	14562095	Global analysis of protein localization in budding yeast.

P42945	UTP10_YEAST	U3 small nucleolar RNA-associated protein 10	15489292	RNA polymerase I transcription and pre-rRNA processing are linked by specific SSU processome components.

Q9LQ98	AFP1_ARATH	Ninja-family protein AFP1	18484180	A small plant-specific protein family of ABI five binding proteins (AFPs) regulates stress response in germinating Arabidopsis seeds and seedlings.

P42837	FIG4_YEAST	Polyphosphoinositide phosphatase	19037259	VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P(2) in yeast and mouse.

Q23858	CALR_DICDI	Calreticulin	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q86UN2	R4RL1_HUMAN	Reticulon-4 receptor-like 1	12694398	Characterization of two novel proteins, NgRH1 and NgRH2, structurally and biochemically homologous to the Nogo-66 receptor.

Q02260	SMD1_YEAST	Small nuclear ribonucleoprotein Sm D1	9012791	Identification of the proteins of the yeast U1 small nuclear ribonucleoprotein complex by mass spectrometry.

Q91Y86	MK08_MOUSE	Mitogen-activated protein kinase 8	10811224	JNK is required for effector T-cell function but not for T-cell activation.

Q15125	EBP_HUMAN	3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	10391219	Mutations in the gene encoding 3-beta-hydroxysteroid- delta(8),delta(7)-isomerase cause X-linked dominant Conradi-Hunermann syndrome.

Q5TEU4	CT007_HUMAN	Probable methyltransferase C20orf7, mitochondrial	18940309	Mutation of C20orf7 disrupts complex I assembly and causes lethal neonatal mitochondrial disease.

O35913	SO1A4_RAT	Solute carrier organic anion transporter family member 1A4	9294213	Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain.

Q7Y1X1	EST_HEVBR	Esterase	15024009	Isolation and characterization of the early nodule-specific protein homologue (Hev b 13), an allergenic lipolytic esterase from Hevea brasiliensis latex.

P43571	BST1_YEAST	GPI inositol-deacylase	11673477	Distinct retrieval and retention mechanisms are required for the quality control of endoplasmic reticulum protein folding.

P51570	GALK1_HUMAN	Galactokinase	7542884	Comparison of the enzymatic activities of human galactokinase GALK1 and a related human galactokinase protein GK2.

Q8BFU0	RSPO2_MOUSE	R-spondin-2	16543246	Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression.

A0MSJ1	CRA1B_DANRE	Collagen alpha-1(XXVII) chain B	20041163	Critical early roles for col27a1a and col27a1b in zebrafish notochord morphogenesis, vertebral mineralization and post-embryonic axial growth.

P80386	AAKB1_RAT	5'-AMP-activated protein kinase subunit beta-1	8626596	Characterization of AMP-activated protein kinase beta and gamma subunits. Assembly of the heterotrimeric complex in vitro.

Q02880	TOP2B_HUMAN	DNA topoisomerase 2-beta	12837248	The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome.

P38820	UBA4_YEAST	Adenylyltransferase and sulfurtransferase UBA4	18664566	Thio-modification of yeast cytosolic tRNA requires a ubiquitin- related system that resembles bacterial sulfur transfer systems.

P53208	YG19_YEAST	Uncharacterized abhydrolase domain-containing protein YGR015C	14562095	Global analysis of protein localization in budding yeast.

O70244	CUBN_RAT	Cubilin	11805171	Megalin and cubilin are endocytic receptors involved in renal clearance of hemoglobin.

O35083	PLCA_MOUSE	1-acyl-sn-glycerol-3-phosphate acyltransferase alpha	9299423	cDNA cloning and expression of murine 1-acyl-sn-glycerol-3-phosphate acyltransferase.

Q56X52	AOX4_ARATH	Alternative oxidase 4, chloroplastic/chromoplastic	11553735	The Arabidopsis immutans mutation affects plastid differentiation and the morphogenesis of white and green sectors in variegated plants.

Q9UHB4	NDOR1_HUMAN	NADPH-dependent diflavin oxidoreductase 1	16140270	Role of a novel dual flavin reductase (NR1) and an associated histidine triad protein (DCS-1) in menadione-induced cytotoxicity.

Q9FIT8	AGD1_ARATH	ADP-ribosylation factor GTPase-activating protein AGD1	18539780	A class one ADP-ribosylation factor GTPase-activating protein is critical for maintaining directional root hair growth in Arabidopsis thaliana.

Q801G2	MPRAB_DANRE	Membrane progestin receptor alpha-B	16899559	Cell-surface expression, progestin binding, and rapid nongenomic signaling of zebrafish membrane progestin receptors alpha and beta in transfected cells.

Q6H543	IAA7_ORYSJ	Auxin-responsive protein IAA7	16200395	Structure and expression analysis of early auxin-responsive Aux/IAA gene family in rice (Oryza sativa).

P50453	SPB9_HUMAN	Serpin B9	8910377	A cytosolic granzyme B inhibitor related to the viral apoptotic regulator cytokine response modifier A is present in cytotoxic lymphocytes.

P0A7A7	PLSB_ECOLI	Glycerol-3-phosphate acyltransferase	6997313	Membrane phospholipid synthesis in Escherichia coli. Identification of the sn-glycerol-3-phosphate acyltransferase polypeptide as the plsB gene product.

Q7LL22	YF71_SCHPO	Uncharacterized protein C3G9.01	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9H4B4	PLK3_HUMAN	Serine/threonine-protein kinase PLK3	8702627	Prk, a cytokine-inducible human protein serine/threonine kinase whose expression appears to be down-regulated in lung carcinomas.

O15371	EIF3D_HUMAN	Eukaryotic translation initiation factor 3 subunit D	17322308	Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry.

Q9P0M4	IL17C_HUMAN	Interleukin-17C	10639155	Cloning and characterization of IL-17B and IL-17C, two new members of the IL-17 cytokine family.

P40427	EXD_DROME	Homeobox protein extradenticle	9463350	Dorsotonals/homothorax, the Drosophila homologue of meis1, interacts with extradenticle in patterning of the embryonic PNS.

P63000	RAC1_HUMAN	Ras-related C3 botulinum toxin substrate 1	11260256	Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42 to atypical protein kinase C.

P92958	KIN11_ARATH	SNF1-related protein kinase catalytic subunit alpha KIN11	11522840	Detection of in vivo protein interactions between Snf1-related kinase subunits with intron-tagged epitope-labelling in plants cells.

Q708S8	ACC2A_DANRE	Amiloride-sensitive cation channel 2-A, neuronal	14970195	A family of acid-sensing ion channels (ASICs) from the zebrafish: widespread e xpression in the central nervous system suggests a conserved role in neuronal communication.

Q9C107	MCL1_SCHPO	Minichromosome loss protein 1	15643072	Mcl1p is a polymerase alpha replication accessory factor important for S-phase DNA damage survival.

Q925J9	MED1_MOUSE	Mediator of RNA polymerase II transcription subunit 1	12037571	Transcription coactivator TRAP220 is required for PPAR gamma 2- stimulated adipogenesis.

Q6H8Q1	ABLM2_HUMAN	Actin-binding LIM protein 2	17194709	Two novel members of the ABLIM protein family, ABLIM-2 and -3, associate with STARS and directly bind F-actin.

O13908	YF3H_SCHPO	Uncharacterized oxidoreductase C22A12.17c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P46721	SO1A2_HUMAN	Solute carrier organic anion transporter family member 1A2	7557095	Molecular and functional characterization of an organic anion transporting polypeptide cloned from human liver.

P52920	NBP35_YEAST	Cytosolic Fe-S cluster assembly factor NBP35	8921898	NBP35 encodes an essential and evolutionary conserved protein in Saccharomyces cerevisiae with homology to a superfamily of bacterial ATPases.

Q9UQL6	HDAC5_HUMAN	Histone deacetylase 5	20188095	Protein kinase C-related kinase targets nuclear localization signals in a subset of class IIa histone deacetylases.

Q9FM65	FLA1_ARATH	Fasciclin-like arabinogalactan protein 1	12805588	Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis.

Q9UHD4	CIDEB_HUMAN	Cell death activator CIDE-B	12429024	Molecular cloning and characterization of CIDE-3, a novel member of the cell-death-inducing DNA-fragmentation-factor (DFF45)-like effector family.

Q8LAS7	CNBL2_ARATH	Calcineurin B-like protein 2	17898163	A protein phosphorylation/dephosphorylation network regulates a plant potassium channel.

P33085	SHAKB_DROME	Innexin shaking-B	9428764	Drosophila Shaking-B protein forms gap junctions in paired Xenopus oocytes.

P63077	GBG8_RAT	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8	7896821	A novel GTP-binding protein gamma-subunit, G gamma 8, is expressed during neurogenesis in the olfactory and vomeronasal neuroepithelia.

Q9P7I6	YJNK_SCHPO	Uncharacterized oxidoreductase C24B10.20	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9BVA0	KTNB1_HUMAN	Katanin p80 WD40-containing subunit B1	10751153	Two domains of p80 katanin regulate microtubule severing and spindle pole targeting by p60 katanin.

Q1ZXQ8	MTAA_DICDI	Centrosomal protein 224	10769206	Dictyostelium DdCP224 is a microtubule-associated protein and a permanent centrosomal resident involved in centrosome duplication.

P05413	FABPH_HUMAN	Fatty acid-binding protein, heart	3421901	Characterization and amino acid sequence of a fatty acid-binding protein from human heart.

P48561	TRF5_YEAST	Poly(A) RNA polymerase protein 1	16431988	Nuclear RNA surveillance in Saccharomyces cerevisiae: Trf4p-dependent polyadenylation of nascent hypomethylated tRNA and an aberrant form of 5S rRNA.

Q08745	RS10A_YEAST	40S ribosomal protein S10-A	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q43468	STIP_SOYBN	Heat shock protein STI	7766904	Isolation and characterization of gmsti, a stress-inducible gene from soybean (Glycine max) coding for a protein belonging to the TPR (tetratricopeptide repeats) family.

P30366	PP11_ARATH	Serine/threonine-protein phosphatase PP1 isozyme 1	1314161	Complementation of the cs dis2-11 cell cycle mutant of Schizosaccharomyces pombe by a protein phosphatase from Arabidopsis thaliana.

P21276	SODF_ARATH	Superoxide dismutase [Fe], chloroplastic	12766230	Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.

Q9Y5Y2	NUBP2_HUMAN	Cytosolic Fe-S cluster assembly factor NUBP2	18573874	Human Nbp35 is essential for both cytosolic iron-sulfur protein assembly and iron homeostasis.

Q3UG20	MLL5_MOUSE	Histone-lysine N-methyltransferase MLL5	18854576	Loss of MLL5 results in pleiotropic hematopoietic defects, reduced neutrophil immune function, and extreme sensitivity to DNA demethylation.

Q9Z0P4	PALM_MOUSE	Paralemmin	9813098	Paralemmin, a prenyl-palmitoyl-anchored phosphoprotein abundant in neurons and implicated in plasma membrane dynamics and cell process formation.

O43186	CRX_HUMAN	Cone-rod homeobox protein	9390563	Cone-rod dystrophy due to mutations in a novel photoreceptor-specific homeobox gene (CRX) essential for maintenance of the photoreceptor.

Q20010	SAS5_CAEEL	Spindle assembly abnormal protein 5	15232593	Centriolar SAS-5 is required for centrosome duplication in C. elegans.

Q8JGN5	BI51A_XENLA	Baculoviral IAP repeat-containing protein 5.1-A	15853809	Apoptosis-inhibiting activities of BIR family proteins in Xenopus egg extracts.

Q8WUH2	TGFA1_HUMAN	Transforming growth factor-beta receptor-associated protein 1	11278302	Transforming growth factor-beta receptor-associated protein 1 is a Smad4 chaperone.

Q9QZI9	SERC3_MOUSE	Serine incorporator 3	12486168	Identification of an axotomy-induced glycosylated protein, AIGP1, possibly involved in cell death triggered by endoplasmic reticulum- Golgi stress.

P0AE52	BCP_ECOLI	Putative peroxiredoxin bcp	10644761	Thioredoxin-dependent hydroperoxide peroxidase activity of bacterioferritin comigratory protein (BCP) as a new member of the thiol-specific antioxidant protein (TSA)/Alkyl hydroperoxide peroxidase C (AhpC) family.

O13640	YGWH_SCHPO	Uncharacterized alpha-1,2-galactosyltransferase C8D2.17	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9C035	TRIM5_HUMAN	Tripartite motif-containing protein 5	12878161	BTBD1 and BTBD2 colocalize to cytoplasmic bodies with the RBCC/tripartite motif protein, TRIM5delta.

Q8TEX9	IPO4_HUMAN	Importin-4	11823430	Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains.

P49711	CTCF_HUMAN	Transcriptional repressor CTCF	18550811	CTCF physically links cohesin to chromatin.

Q9S841	PSBO2_ARATH	Oxygen-evolving enhancer protein 1-2, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

P40546	FAF1_YEAST	Protein FAF1	15178413	Functional and physical interactions of Faf1p, a Saccharomyces cerevisiae nucleolar protein.

P20823	HNF1A_HUMAN	Hepatocyte nuclear factor 1-alpha	12453420	Diabetes mutations delineate an atypical POU domain in HNF-1alpha.

Q99680	GPR22_HUMAN	Probable G-protein coupled receptor 22	9073069	Cloning and chromosomal mapping of four putative novel human G- protein-coupled receptor genes.

P23574	GBRG1_RAT	Gamma-aminobutyric acid receptor subunit gamma-1	2170110	Structural and functional characterization of the gamma 1 subunit of GABAA/benzodiazepine receptors.

P34791	CP20C_ARATH	Peptidyl-prolyl cis-trans isomerase CYP20-3, chloroplastic	11719511	Proteome map of the chloroplast lumen of Arabidopsis thaliana.

Q8TBC4	UBA3_HUMAN	NEDD8-activating enzyme E1 catalytic subunit	9694792	A new NEDD8-ligating system for cullin-4A.

Q8TCT0	CERK1_HUMAN	Ceramide kinase	11956206	Ceramide kinase, a novel lipid kinase. Molecular cloning and functional characterization.

O54949	NLK_MOUSE	Serine/threonine-protein kinase NLK	15082531	Wnt-1 signal induces phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK.

P08908	5HT1A_HUMAN	5-hydroxytryptamine receptor 1A	3138543	The genomic clone G-21 which resembles a beta-adrenergic receptor sequence encodes the 5-HT1A receptor.

Q8R5K5	UTP11_RAT	Probable U3 small nucleolar RNA-associated protein 11	11860508	Characterizing CGI-94 (comparative gene identification-94) which is down-regulated in the hippocampus of early stage Alzheimer's disease brain.

Q08702	APTX_YEAST	Aprataxin-like protein	14562095	Global analysis of protein localization in budding yeast.

P22217	TRX1_YEAST	Thioredoxin-1	9015301	A heterodimer of thioredoxin and I(B)2 cooperates with Sec18p (NSF) to promote yeast vacuole inheritance.

Q90Z12	HES4A_XENLA	Transcription factor HES-4-A	15689375	The Notch-target gene hairy2a impedes the involution of notochordal cells by promoting floor plate fates in Xenopus embryos.

Q04667	HES3_RAT	Transcription factor HES-3	1340473	Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split.

P38342	TSC10_YEAST	3-ketodihydrosphingosine reductase TSC10	9804843	The Saccharomyces cerevisiae TSC10/YBR265w gene encoding 3- ketosphinganine reductase is identified in a screen for temperature- sensitive suppressors of the Ca2+-sensitive csg2Delta mutant.

Q9VLT5	POE_DROME	Protein purity of essence	8244010	Toward a molecular genetic analysis of spermatogenesis in Drosophila melanogaster: characterization of male-sterile mutants generated by single P element mutagenesis.

Q9FLT2	IPMKB_ARATH	Inositol polyphosphate multikinase beta	16107538	Generation of phytate-free seeds in Arabidopsis through disruption of inositol polyphosphate kinases.

P38659	PDIA4_RAT	Protein disulfide-isomerase A4	8477750	CaBP2 is a rat homolog of ERp72 with proteindisulfide isomerase activity.

P62241	RS8_HUMAN	40S ribosomal protein S8	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

Q06787	FMR1_HUMAN	Fragile X mental retardation 1 protein	7692601	FMR1 protein: conserved RNP family domains and selective RNA binding.

Q9EP52	TWSG1_MOUSE	Twisted gastrulation protein homolog 1	15843411	Sirenomelia in Bmp7 and Tsg compound mutant mice: requirement for Bmp signaling in the development of ventral posterior mesoderm.

O94602	YC8F_SCHPO	Uncharacterized protein C622.15c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q42484	RPS2_ARATH	Disease resistance protein RPS2	12581526	Initiation of RPS2-specified disease resistance in Arabidopsis is coupled to the AvrRpt2-directed elimination of RIN4.

C0LGF4	FEI1_ARATH	LRR receptor-like serine/threonine-protein kinase FEI 1	19017745	Two leucine-rich repeat receptor kinases mediate signaling, linking cell wall biosynthesis and ACC synthase in Arabidopsis.

P35200	MSF1_YEAST	Protein MSF1	14562095	Global analysis of protein localization in budding yeast.

Q9UBB4	ATX10_HUMAN	Ataxin-10	15201271	Ataxin-10, the spinocerebellar ataxia type 10 neurodegenerative disorder protein, is essential for survival of cerebellar neurons.

Q9W1R5	VIR_DROME	Protein virilizer	12444081	Biochemical function of female-lethal (2)D/Wilms' tumor suppressor-1- associated proteins in alternative pre-mRNA splicing.

P14141	CAH3_RAT	Carbonic anhydrase 3	10900145	Suppression of carbonic anhydrase III in rat liver by a dioxin- related toxic compound, coplanar polychlorinated biphenyl, 3,3',4,4',5-pentachlorobiphenyl.

P38149	DUG2_YEAST	Probable di- and tripeptidase DUG2	14562095	Global analysis of protein localization in budding yeast.

P38872	ADY1_YEAST	Prospore formation at selected spindle poles protein 1	11553705	ADY1, a novel gene required for prospore membrane formation at selected spindle poles in Saccharomyces cerevisiae.

Q42588	SAT1_ARATH	Serine acetyltransferase 1, chloroplastic	8867790	Serine acetyltransferase from Arabidopsis thaliana can functionally complement the cysteine requirement of a cysE mutant strain of Escherichia coli.

Q14108	SCRB2_HUMAN	Lysosome membrane protein 2	1374238	Isolation and sequencing of a cDNA clone encoding the 85 kDa human lysosomal sialoglycoprotein (hLGP85) in human metastatic pancreas islet tumor cells.

Q8GW19	FACE2_ARATH	CAAX prenyl protease 2	18641086	Functional analysis of Arabidopsis postprenylation CaaX processing enzymes and their function in subcellular protein targeting.

P49889	ST1E3_RAT	Estrogen sulfotransferase, isoform 3	7857871	Isolation and expression of an isoform of rat estrogen sulfotransferase.

P29496	MCM5_YEAST	Minichromosome maintenance protein 5	2044962	A group of interacting yeast DNA replication genes.

Q9H346	O52D1_HUMAN	Olfactory receptor 52D1	11121057	Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.

Q8VI24	SATB2_MOUSE	DNA-binding protein SATB2	16751105	SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation.

Q18688	HSP90_CAEEL	Heat shock protein 90	12950278	Caenorhabditis elegans DAF-21 (HSP90) is characteristically and predominantly expressed in germline cells: spatial and temporal analysis.

Q9JKE3	SCAM5_RAT	Secretory carrier-associated membrane protein 5	11050114	Novel SCAMPs lacking NPF repeats: ubiquitous and synaptic vesicle- specific forms implicate SCAMPs in multiple membrane-trafficking functions.

O43707	ACTN4_HUMAN	Alpha-actinin-4	9508771	Actinin-4, a novel actin-bundling protein associated with cell motility and cancer invasion.

O04983	ACCC_ARATH	Biotin carboxylase, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

P22894	MMP8_HUMAN	Neutrophil collagenase	2164002	Human neutrophil collagenase. A distinct gene product with homology to other matrix metalloproteinases.

P78539	SRPX_HUMAN	Sushi repeat-containing protein SRPX	8634708	A gene (SRPX) encoding a sushi-repeat-containing protein is deleted in patients with X-linked retinitis pigmentosa.

Q95LI0	DB118_MACMU	Beta-defensin 118	11564719	Primate epididymis-specific proteins: characterization of ESC42, a novel protein containing a trefoil-like motif in monkey and human.

P38282	SP381_YEAST	Pre-mRNA-splicing factor SPP381	9858581	Elevated levels of a U4/U6.U5 snRNP-associated protein, Spp381p, rescue a mutant defective in spliceosome maturation.

O22213	CKX1_ARATH	Cytokinin dehydrogenase 1	14555694	Cytokinin-deficient transgenic Arabidopsis plants show multiple developmental alterations indicating opposite functions of cytokinins in the regulation of shoot and root meristem activity.

O70342	NPY5R_MOUSE	Neuropeptide Y receptor type 5	9802393	Molecular biology and pharmacology of multiple NPY Y5 receptor species homologs.

P59241	STK6_RAT	Serine/threonine-protein kinase 6	12124350	Centrosome amplification and overexpression of aurora A are early events in rat mammary carcinogenesis.

Q9Y2Y8	PRG3_HUMAN	Proteoglycan 3	10318872	A novel and highly divergent homolog of human eosinophil granule major basic protein.

P98177	FOXO4_HUMAN	Forkhead box protein O4	10217147	Direct control of the forkhead transcription factor AFX by protein kinase B.

P62492	RB11A_MOUSE	Ras-related protein Rab-11A	20190753	Mutations in VIPAR cause an arthrogryposis, renal dysfunction and cholestasis syndrome phenotype with defects in epithelial polarization.

P39306	ULAF_ECOLI	L-ribulose-5-phosphate 4-epimerase ulaF	14996803	Regulation of expression of the divergent ulaG and ulaABCDEF operons involved in L-ascorbate dissimilation in Escherichia coli.

Q84J37	LAC15_ARATH	Laccase-15	16779554	Involvement of AtLAC15 in lignin synthesis in seeds and in root elongation of Arabidopsis.

O43914	TYOBP_HUMAN	TYRO protein tyrosine kinase-binding protein	9490415	Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells.

O83369	SLYD_TREPA	FKBP-type peptidyl-prolyl cis-trans isomerase slyD	16388577	SlyD proteins from different species exhibit high prolyl isomerase and chaperone activities.

Q9QZS8	SH2D3_MOUSE	SH2 domain-containing protein 3C	10542222	A novel signaling intermediate, SHEP1, directly couples Eph receptors to R-Ras and Rap1A.

Q9LPI7	NAC12_ARATH	NAC domain-containing protein 12	17114348	SND1, a NAC domain transcription factor, is a key regulator of secondary wall synthesis in fibers of Arabidopsis.

Q13118	KLF10_HUMAN	Krueppel-like factor 10	8532536	Identification of a novel TGF-beta-regulated gene encoding a putative zinc finger protein in human osteoblasts.

O65674	ASK12_ARATH	SKP1-like protein 12	14749489	Expression and interaction analysis of Arabidopsis Skp1-related genes.

Q9SQI2	GIGAN_ARATH	Protein GIGANTEA	10920210	GIGANTEA is a nuclear protein involved in phytochrome signaling in Arabidopsis.

O60721	NCKX1_HUMAN	Sodium/potassium/calcium exchanger 1	9856482	Chromosomal localization and genomic organization of the human retinal rod Na-Ca+K exchanger.

O95196	CSPG5_HUMAN	Chondroitin sulfate proteoglycan 5	12885772	CALEB/NGC interacts with the Golgi-associated protein PIST.

P49739	MCM3M_XENLA	Maternal DNA replication licensing factor mcm3	16369567	The ATPase activity of MCM2-7 is dispensable for pre-RC assembly but is required for DNA unwinding.

P47999	CYSKP_ARATH	Cysteine synthase, chloroplastic/chromoplastic	10940562	Genomic and functional characterization of the oas gene family encoding O-acetylserine (thiol) lyases, enzymes catalyzing the final step in cysteine biosynthesis in Arabidopsis thaliana.

P51159	RB27A_HUMAN	Ras-related protein Rab-27A	18812475	A newly identified isoform of Slp2a associates with Rab27a in cytotoxic T cells and participates to cytotoxic granule secretion.

P22003	BMP5_HUMAN	Bone morphogenetic protein 5	2263636	Identification of transforming growth factor beta family members present in bone-inductive protein purified from bovine bone.

P40121	CAPG_HUMAN	Macrophage-capping protein	1322908	Molecular cloning of human macrophage capping protein cDNA. A unique member of the gelsolin/villin family expressed primarily in macrophages.

P62306	RUXF_HUMAN	Small nuclear ribonucleoprotein F	7744013	snRNP Sm proteins share two evolutionarily conserved sequence motifs which are involved in Sm protein-protein interactions.

Q92847	GHSR_HUMAN	Growth hormone secretagogue receptor type 1	16511605	Loss of constitutive activity of the growth hormone secretagogue receptor in familial short stature.

Q8GYJ3	KRP4_ARATH	Cyclin-dependent kinase inhibitor 4	16376885	Arabidopsis KRPs have distinct inhibitory activity toward cyclin D2- associated kinases, including plant-specific B-type cyclin-dependent kinase.

Q9NS23	RASF1_HUMAN	Ras association domain-containing protein 1	14729613	Identification of the E1A-regulated transcription factor p120 E4F as an interacting partner of the RASSF1A candidate tumor suppressor gene.

Q9M548	DRM2_ARATH	DNA (cytosine-5)-methyltransferase DRM2	12121623	Role of the arabidopsis DRM methyltransferases in de novo DNA methylation and gene silencing.

Q12331	YFAS1_YEAST	FAS1 domain-containing protein YDR262W	14562095	Global analysis of protein localization in budding yeast.

P53954	ALG11_YEAST	Alpha-1,2-mannosyltransferase ALG11	11278778	The yeast ALG11 gene specifies addition of the terminal alpha 1,2-Man to the Man5GlcNAc2-PP-dolichol N-glycosylation intermediate formed on the cytosolic side of the endoplasmic reticulum.

Q96QU1	PCD15_HUMAN	Protocadherin-15	16369489	Protocadherin 15 (PCDH15): a new secreted isoform and a potential marker for NK/T cell lymphomas.

P79483	DRB3_HUMAN	HLA class II histocompatibility antigen, DR beta 3 chain	6414998	Molecular analysis of the genes for human class II antigens of the major histocompatibility complex.

P42845	STB1_YEAST	Protein STB1	9393435	Identification of the Saccharomyces cerevisiae genes STB1-STB5 encoding Sin3p binding proteins.

Q15797	SMAD1_HUMAN	Mothers against decapentaplegic homolog 1	10708949	TGF-beta signaling by Smad proteins.

Q1G3K7	PRA1C_ARATH	PRA1 family protein C	18583532	The PRA1 gene family in Arabidopsis.

O94751	BUB1_SCHPO	Checkpoint serine/threonine-protein kinase bub1	9864354	Fission yeast Bub1 is a mitotic centromere protein essential for the spindle checkpoint and the preservation of correct ploidy through mitosis.

Q16512	PKN1_HUMAN	Serine/threonine-protein kinase N1	12514133	A novel inducible transactivation domain in the androgen receptor: implications for PRK in prostate cancer.

Q9NPC7	MYNN_HUMAN	Myoneurin	10873615	Myoneurin, a novel member of the BTB/POZ-zinc finger family highly expressed in human muscle.

P49189	AL9A1_HUMAN	4-trimethylaminobutyraldehyde dehydrogenase	2925663	Human aldehyde dehydrogenase. Purification and characterization of a third isozyme with low Km for gamma-aminobutyraldehyde.

Q00723	PRP38_YEAST	Pre-mRNA-splicing factor 38	9582287	Progression through the spliceosome cycle requires Prp38p function for U4/U6 snRNA dissociation.

Q9VH48	CARM1_DROME	Probable histone-arginine methyltransferase CARMER	14976192	An arginine-histone methyltransferase, CARMER, coordinates ecdysone- mediated apoptosis in Drosophila cells.

Q91903	ELAV2_XENLA	ELAV-like protein 2	9174163	Subcellular distribution of Xenopus XEL-1 protein, a member of the neuron-specific ELAV/Hu family, revealed by epitope tagging.

P21565	SRP54_SCHPO	Signal recognition particle 54 kDa protein homolog	7969124	The Srp54 GTPase is essential for protein export in the fission yeast Schizosaccharomyces pombe.

Q04212	ARA2_YEAST	D-arabinose 1-dehydrogenase	17097644	NAD+-specific D-arabinose dehydrogenase and its contribution to erythroascorbic acid production in Saccharomyces cerevisiae.

Q13404	UB2V1_HUMAN	Ubiquitin-conjugating enzyme E2 variant 1	9305758	CROC-1 encodes a protein which mediates transcriptional activation of the human FOS promoter.

P57081	WDR4_HUMAN	tRNA (guanine-N(7)-)-methyltransferase subunit WDR4	12403464	Two proteins that form a complex are required for 7-methylguanosine modification of yeast tRNA.

P51521	OVO_DROME	Protein ovo	10648246	OVO transcription factors function antagonistically in the Drosophila female germline.

Q55BV5	PRS4_DICDI	26S protease regulatory subunit 4 homolog	7862164	Growth and developmental functions of a human immunodeficiency virus Tat-binding protein/26S protease subunit homolog from Dictyostelium discoideum.

Q9W596	FUTSC_DROME	Microtubule-associated protein futsch	11733059	Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function.

P02708	ACHA_HUMAN	Acetylcholine receptor subunit alpha	9221765	Slow-channel myasthenic syndrome caused by enhanced activation, desensitization, and agonist binding affinity attributable to mutation in the M2 domain of the acetylcholine receptor alpha subunit.

Q8CFW1	ANO2_MOUSE	Anoctamin-2	19475416	TMEM16B induces chloride currents activated by calcium in mammalian cells.

P70041	CER1_XENLA	Cerberus	8757128	Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer.

Q9S713	STT7_ARATH	Serine/threonine-protein kinase SNT7, chloroplastic	15729347	State transitions and light adaptation require chloroplast thylakoid protein kinase STN7.

Q62915	CSKP_RAT	Peripheral plasma membrane protein CASK	8786425	CASK: a novel dlg/PSD95 homolog with an N-terminal calmodulin- dependent protein kinase domain identified by interaction with neurexins.

Q8IS21	GEFB_DICDI	Ras guanine nucleotide exchange factor B	11102804	A novel Dictyostelium RasGEF is required for normal endocytosis, cell motility and multicellular development.

O60184	CYC8_SCHPO	General transcriptional corepressor ssn6	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q38937	RAC5_ARATH	Rac-like GTP-binding protein ARAC5	11387211	Arabidopsis thaliana Rop GTPases are localized to tips of root hairs and control polar growth.

P53725	MPP6_YEAST	M-phase phosphoprotein 6 homolog	18591258	A yeast exosome cofactor, Mpp6, functions in RNA surveillance and in the degradation of noncoding RNA transcripts.

P32246	CCR1_HUMAN	C-C chemokine receptor type 1	7683036	Structure and functional expression of the human macrophage inflammatory protein 1 alpha/RANTES receptor.

P42838	LEM3_YEAST	Alkylphosphocholine resistance protein LEM3	12842877	Lem3p is essential for the uptake and potency of alkylphosphocholine drugs, edelfosine and miltefosine.

P21784	RAG2_MOUSE	V(D)J recombination-activating protein 2	19396172	Structure of the RAG1 nonamer binding domain with DNA reveals a dimer that mediates DNA synapsis.

Q9NZK5	CECR1_HUMAN	Adenosine deaminase CECR1	10756095	The human homolog of insect-derived growth factor, CECR1, is a candidate gene for features of cat eye syndrome.

Q8RWN9	OPD22_ARATH	Dihydrolipoyllysine-residue acetyltransferase component 2 of pyruvate dehydrogenase complex, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q9LV87	PEP1_ARATH	Elicitor peptide 1	18824048	Structure-activity studies of AtPep1, a plant peptide signal involved in the innate immune response.

O95971	BY55_HUMAN	CD160 antigen	9973372	MHC class I triggering by a novel cell surface ligand costimulates proliferation of activated human T cells.

Q86XR8	CEP57_HUMAN	Centrosomal protein of 57 kDa	12717444	Translokin is an intracellular mediator of FGF-2 trafficking.

P49893	WN11B_XENLA	Protein Wnt-11b	7739543	Identification of distinct classes and functional domains of Wnts through expression of wild-type and chimeric proteins in Xenopus embryos.

Q38914	ANT_ARATH	AP2-like ethylene-responsive transcription factor ANT	11058102	DNA binding properties of the Arabidopsis floral development protein AINTEGUMENTA.

Q16760	DGKD_HUMAN	Diacylglycerol kinase delta	8626538	Molecular cloning of a novel diacylglycerol kinase isozyme with a pleckstrin homology domain and a C-terminal tail similar to those of the EPH family of protein-tyrosine kinases.

P36046	MIA40_YEAST	Mitochondrial intermembrane space import and assembly protein 40	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q9JHS2	HIF3A_RAT	Hypoxia-inducible factor 3-alpha	11237857	Perivenous expression of the mRNA of the three hypoxia-inducible factor a-subunits HIF-1a, HIF2a and HIF3a in rat liver.

Q9VC57	ATLAS_DROME	Atlastin	19341724	Drosophila Atlastin regulates the stability of muscle microtubules and is required for synapse development.

Q9UBK8	MTRR_HUMAN	Methionine synthase reductase	9501215	Cloning and mapping of a cDNA for methionine synthase reductase, a flavoprotein defective in patients with homocystinuria.

P03965	CARB_YEAST	Carbamoyl-phosphate synthase arginine-specific large chain	6358221	Yeast carbamyl phosphate synthetase. Structure of the yeast gene and homology to Escherichia coli carbamyl phosphate synthetase.

Q99287	SEY1_YEAST	Protein SEY1	14562095	Global analysis of protein localization in budding yeast.

O75716	STK16_HUMAN	Serine/threonine-protein kinase 16	9712705	Cloning, expression analysis, and functional characterization of PKL12, a member of a new subfamily of ser/thr kinases.

Q6X5Y6	WRI1_ARATH	Ethylene-responsive transcription factor WRI1	15753106	ACTIVATOR of Spomin::LUC1/WRINKLED1 of Arabidopsis thaliana transactivates sugar-inducible promoters.

O75461	E2F6_HUMAN	Transcription factor E2F6	9501179	E2F-6, a member of the E2F family that can behave as a transcriptional repressor.

P49803	RGS7_RAT	Regulator of G-protein signaling 7	10092682	RGS7 and RGS8 differentially accelerate G protein-mediated modulation of K+ currents.

Q08117	AES_HUMAN	Amino-terminal enhancer of split	8365415	Molecular cloning and expression of mouse and human cDNA encoding AES and ESG proteins with strong similarity to Drosophila enhancer of split groucho protein.

Q7XJM2	CCD7_ARATH	Carotenoid cleavage dioxygenase 7, chloroplastic	16507088	Characterization of three members of the Arabidopsis carotenoid cleavage dioxygenase family demonstrates the divergent roles of this multifunctional enzyme family.

Q9Y4L5	RN115_HUMAN	E3 ubiquitin-protein ligase RNF115	16925951	Novel RING E3 ubiquitin ligases in breast cancer.

Q13045	FLII_HUMAN	Protein flightless-1 homolog	9177775	Genomic structure, evolution, and expression of human FLII, a gelsolin and leucine-rich-repeat family member: overlap with LLGL.

O43294	TGFI1_HUMAN	Transforming growth factor beta-1-induced transcript 1 protein	9756887	Interaction of Hic-5, A senescence-related protein, with focal adhesion kinase.

Q8RUN2	LOG1_ARATH	Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG1	19837870	Functional analyses of LONELY GUY cytokinin-activating enzymes reveal the importance of the direct activation pathway in Arabidopsis.

P53192	GET1_YEAST	Golgi to ER traffic protein 1	16269340	Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile.

P61106	RAB14_HUMAN	Ras-related protein Rab-14	16034420	Structural basis of family-wide Rab GTPase recognition by rabenosyn- 5.

Q9Z301	PER2_RAT	Period circadian protein homolog 2	11533252	Nuclear entry mechanism of rat PER2 (rPER2): role of rPER2 in nuclear localization of CRY protein.

P0ACG8	HSLR_ECOLI	Heat shock protein 15	9867837	A new heat shock protein that binds nucleic acids.

Q9SEX2	KTNA1_ARATH	Katanin p60 ATPase-containing subunit	11283338	A katanin-like protein regulates normal cell wall biosynthesis and cell elongation.

P51650	SSDH_RAT	Succinate-semialdehyde dehydrogenase, mitochondrial	7814412	Molecular cloning of the mature NAD(+)-dependent succinic semialdehyde dehydrogenase from rat and human. cDNA isolation, evolutionary homology, and tissue expression.

P62826	RAN_HUMAN	GTP-binding nuclear protein Ran	18591255	A survivin-ran complex regulates spindle formation in tumor cells.

Q9ZRT1	GR1_ARATH	Protein gamma response 1	11023598	Molecular cloning and developmental expression of AtGR1, a new growth-related Arabidopsis gene strongly induced by ionizing radiation.

Q9C9X3	ANXD5_ARATH	Annexin D5	16531057	Expression profiling of the Arabidopsis annexin gene family during germination, de-etiolation and abiotic stress.

P19018	TRA2_DROME	Transformer-2 sex-determining protein	8334698	A splicing enhancer complex controls alternative splicing of doublesex pre-mRNA.

Q9H4M3	FBX44_HUMAN	F-box only protein 44	18203720	Diversity in tissue expression, substrate binding, and SCF complex formation for a lectin family of ubiquitin ligases.

Q9FKW6	FNRL1_ARATH	Ferredoxin--NADP reductase, leaf isozyme 1, chloroplastic	17335513	Structural and functional characterization of ferredoxin-NADP+- oxidoreductase using knock-out mutants of Arabidopsis.

O60070	ASH2_SCHPO	Set1 complex component ash2	12488447	High conservation of the Set1/Rad6 axis of histone 3 lysine 4 methylation in budding and fission yeasts.

Q21443	LMN1_CAEEL	Lamin-1	11071918	Essential roles for Caenorhabditis elegans lamin gene in nuclear organization, cell cycle progression, and spatial organization of nuclear pore complexes.

Q9WVI9	JIP1_MOUSE	C-Jun-amino-terminal kinase-interacting protein 1	9235893	A cytoplasmic inhibitor of the JNK signal transduction pathway.

Q16873	LTC4S_HUMAN	Leukotriene C4 synthase	19233132	Distinct parts of leukotriene C(4) synthase interact with 5- lipoxygenase and 5-lipoxygenase activating protein.

O57437	DAZLA_XENLA	Deleted in azoospermia-like-A	15292452	Localization of RNAs to the mitochondrial cloud in Xenopus oocytes through entrapment and association with endoplasmic reticulum.

Q8WZJ7	C1TC_SCHPO	C-1-tetrahydrofolate synthase, cytoplasmic	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q08828	ADCY1_HUMAN	Adenylate cyclase type 1	8314585	Cloning, chromosomal mapping, and expression of human fetal brain type I adenylyl cyclase.

Q63622	DLG2_RAT	Disks large homolog 2	15304517	An alternatively spliced isoform of PSD-93/chapsyn 110 binds to the inwardly rectifying potassium channel, Kir2.1.

O88456	CPNS1_MOUSE	Calpain small subunit 1	10825211	Disruption of the murine calpain small subunit gene, Capn4: calpain is essential for embryonic development but not for cell growth and division.

Q08686	THTR_YEAST	Putative thiosulfate sulfurtransferase	14562095	Global analysis of protein localization in budding yeast.

P52757	CHIO_HUMAN	Beta-chimaerin	8175705	Cerebellar beta 2-chimaerin, a GTPase-activating protein for p21 ras- related rac is specifically expressed in granule cells and has a unique N-terminal SH2 domain.

Q9FMA5	C85A1_ARATH	Cytochrome P450 85A1	11402205	Brassinosteroid-6-oxidases from Arabidopsis and tomato catalyze multiple C-6 oxidations in brassinosteroid biosynthesis.

Q9XFD1	NCBP2_ARATH	Nuclear cap-binding protein subunit 2	11867224	Cloning and characterization of two subunits of Arabidopsis thaliana nuclear cap-binding complex.

Q9GYU8	NUP88_DROME	Nuclear pore complex protein Nup88	14638854	The Drosophila nucleoporin DNup88 localizes DNup214 and CRM1 on the nuclear envelope and attenuates NES-mediated nuclear export.

Q9UBF8	PI4KB_HUMAN	Phosphatidylinositol 4-kinase beta	9020160	Cloning and characterization of a wortmannin-sensitive human phosphatidylinositol 4-kinase.

P43601	ATG18_YEAST	Autophagy-related protein 18	11739783	Cvt18/Gsa12 is required for cytoplasm-to-vacuole transport, pexophagy, and autophagy in Saccharomyces cerevisiae and Pichia pastoris.

Q7Z7A3	CTU1_HUMAN	Cytoplasmic tRNA 2-thiolation protein 1	19017811	A functional proteomics approach links the ubiquitin-related modifier Urm1 to a tRNA modification pathway.

Q92830	KAT2A_HUMAN	Histone acetyltransferase KAT2A	11564863	Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage- binding factors in vivo.

P43404	ZAP70_MOUSE	Tyrosine-protein kinase ZAP-70	8196616	Interactions of p59fyn and ZAP-70 with T-cell receptor activation motifs: defining the nature of a signalling motif.

Q54B10	REDA_DICDI	NADPH oxidoreductase A	18218133	The P450 oxidoreductase, RedA, controls development beyond the mound stage in Dictyostelium discoideum.

P51796	CLCN5_RAT	H(+)/Cl(-) exchange transporter 5	8626585	Identification of a new outwardly rectifying Cl- channel that belongs to a subfamily of the ClC Cl- channels.

Q9UL25	RAB21_HUMAN	Ras-related protein Rab-21	16034420	Structural basis of family-wide Rab GTPase recognition by rabenosyn- 5.

P35329	CD22_MOUSE	B-cell receptor CD22	10748054	CD22 forms a quaternary complex with SHIP, Grb2, and Shc. A pathway for regulation of B lymphocyte antigen receptor-induced calcium flux.

Q13077	TRAF1_HUMAN	TNF receptor-associated factor 1	8069916	A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor.

Q9QYH6	MAGD1_MOUSE	Melanoma-associated antigen D1	11084035	Dlxin-1, a novel protein that binds Dlx5 and regulates its transcriptional function.

Q22006	PRO1_CAEEL	Pre-rRNA-processing protein pro-1	16876152	Alterations in ribosome biogenesis cause specific defects in C. elegans hermaphrodite gonadogenesis.

P34078	LTV1_YEAST	Protein LTV1	15611164	Genetic and biochemical interactions among Yar1, Ltv1 and Rps3 define novel links between environmental stress and ribosome biogenesis in Saccharomyces cerevisiae.

Q16204	CCDC6_HUMAN	Coiled-coil domain-containing protein 6	8058316	Cloning and characterization of H4 (D10S170), a gene involved in RET rearrangements in vivo.

Q39234	TGA3_ARATH	Transcription factor TGA3	10659709	NPR1 differentially interacts with members of the TGA/OBF family of transcription factors that bind an element of the PR-1 gene required for induction by salicylic acid.

Q09772	RDH54_SCHPO	Meiotic recombination protein rdh54	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O00541	PESC_HUMAN	Pescadillo homolog	16043514	Mammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferation.

Q9H1J1	REN3A_HUMAN	Regulator of nonsense transcripts 3A	11163187	Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon.

Q95QD7	LIN54_CAEEL	Protein lin-54	17075059	Some C. elegans class B synthetic multivulva proteins encode a conserved LIN-35 Rb-containing complex distinct from a NuRD-like complex.

P36872	2ABA_DROME	Protein phosphatase PP2A 55 kDa regulatory subunit	8383623	Mutation of twins encoding a regulator of protein phosphatase 2A leads to pattern duplication in Drosophila imaginal discs.

P47883	OR3A4_HUMAN	Olfactory receptor 3A4	8004088	Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire.

Q55EX9	Y8948_DICDI	Putative methyltransferase DDB_G0268948	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

Q9UTI5	VPS29_SCHPO	Vacuolar protein sorting-associated protein 29	16622069	Vacuolar protein sorting receptor in Schizosaccharomyces pombe.

Q9WU60	ATRN_MOUSE	Attractin	10086355	The mahogany protein is a receptor involved in suppression of obesity.

Q9VD83	BURS_DROME	Bursicon	15811337	Drosophila molting neurohormone bursicon is a heterodimer and the natural agonist of the orphan receptor DLGR2.

B5LUR1	FALX9_LITFA	Preprofallaxidin-9	18803332	The fallaxidin peptides from the skin secretion of the eastern dwarf tree frog Litoria fallax. Sequence determination by positive and negative ion electrospray mass spectrometry: antimicrobial activity and cDNA cloning of the fallaxidins.

P78504	JAG1_HUMAN	Protein jagged-1	9207788	Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1.

A0A1F4	EYS_DROME	Protein eyes shut	17011488	The agrin/perlecan-related protein eyes shut is essential for epithelial lumen formation in the Drosophila retina.

P40992	RRN7_YEAST	RNA polymerase I-specific transcription initiation factor RRN7	7958901	RRN6 and RRN7 encode subunits of a multiprotein complex essential for the initiation of rDNA transcription by RNA polymerase I in Saccharomyces cerevisiae.

P45951	ARP_ARATH	Apurinic endonuclease-redox protein	7512729	The Arabidopsis thaliana apurinic endonuclease Arp reduces human transcription factors Fos and Jun.

Q00728	H2A4_RAT	Histone H2A type 4	2011515	Presence of a bi-directional S phase-specific transcription regulatory element in the promoter shared by testis-specific TH2A and TH2B histone genes.

Q08957	AFT2_YEAST	Iron-regulated transcriptional activator AFT2	11448968	Aft2p, a novel iron-regulated transcription activator that modulates, with Aft1p, intracellular iron use and resistance to oxidative stress in yeast.

Q8R2Z5	VWA1_MOUSE	von Willebrand factor A domain-containing protein 1	12062410	WARP is a new member of the von Willebrand factor A-domain superfamily of extracellular matrix proteins.

P28465	WNT2_DROME	Protein Wnt-2	11717401	Seven Wnt homologues in Drosophila: a case study of the developing tracheae.

O43687	AKA7A_HUMAN	A-kinase anchor protein 7 isoforms alpha and beta	10613906	Alternative splicing regulates the subcellular localization of A- kinase anchoring protein 18 isoforms.

Q9ES52	SHIP1_MOUSE	Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1	12161749	SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclasts.

P08641	CADH1_CHICK	Cadherin-1	1638632	Identification of a neural alpha-catenin as a key regulator of cadherin function and multicellular organization.

Q04305	UTP15_YEAST	U3 small nucleolar RNA-associated protein 15	12068309	A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis.

P63165	SUMO1_HUMAN	Small ubiquitin-related modifier 1	18408734	RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation.

Q21049	LIPA_CAEEL	Liprin-alpha	10517634	The liprin protein SYD-2 regulates the differentiation of presynaptic termini in C. elegans.

O54922	EXOC7_RAT	Exocyst complex component 7	9405631	Subunit structure of the mammalian exocyst complex.

Q07844	RIX7_YEAST	Ribosome biogenesis ATPase RIX7	11447111	A nuclear AAA-type ATPase (Rix7p) is required for biogenesis and nuclear export of 60S ribosomal subunits.

Q8TFG6	PPK18_SCHPO	Serine/threonine-protein kinase ppk18	15821139	Systematic deletion analysis of fission yeast protein kinases.

P83916	CBX1_HUMAN	Chromobox protein homolog 1	9169582	Heterochromatin protein HP1Hsbeta (p25beta) and its localization with centromeres in mitosis.

Q5SXI5	ZN496_MOUSE	Zinc finger protein 496	15169884	Nizp1, a novel multitype zinc finger protein that interacts with the NSD1 histone lysine methyltransferase through a unique C2HR motif.

O77059	CRY1_DROME	Cryptochrome-1	10063806	A putative blue-light receptor from Drosophila melanogaster.

Q8CGT6	PIWL4_MOUSE	Piwi-like protein 4	18381894	DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes.

Q9D7K2	TEN1L_MOUSE	CST complex subunit TEN1	19854130	RPA-like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathway.

Q12071	VPS54_YEAST	Vacuolar protein sorting-associated protein 54	9914379	Regulation of tubulin polypeptides and microtubule function: Luv1p interacts with the beta-tubulin binding protein Rbl2p.

P26772	CH10_RAT	10 kDa heat shock protein, mitochondrial	7904573	Isolation of a cDNA clone specifying rat chaperonin 10, a stress- inducible mitochondrial matrix protein synthesised without a cleavable presequence.

Q9R050	SSBP3_RAT	Single-stranded DNA-binding protein 3	10524251	Cloning of a cDNA encoding a sequence-specific single-stranded-DNA- binding protein from Rattus norvegicus.

P42454	RURE_ACIAD	Rubredoxin-NAD(+) reductase	10400587	The genes rubA and rubB for alkane degradation in Acinetobacter sp. strain ADP1 are in an operon with estB, encoding an esterase, and oxyR.

Q9UPU3	SORC3_HUMAN	VPS10 domain-containing receptor SorCS3	11499680	The genes for the human VPS10 domain-containing receptors are large and contain many small exons.

Q559R0	SAR1A_DICDI	GTP-binding protein Sar1A	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q924T3	XRCC4_MOUSE	DNA repair protein XRCC4	9875844	A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis.

Q12175	MSH5_YEAST	MutS protein homolog 5	9374523	Conserved properties between functionally distinct MutS homologs in yeast.

Q9Y664	KPTN_HUMAN	Kaptin	1372044	An actin-associated protein present in the microtubule organizing center and the growth cones of PC-12 cells.

Q15831	STK11_HUMAN	Serine/threonine-protein kinase 11	9428765	A serine/threonine kinase gene defective in Peutz-Jeghers syndrome.

Q8R4T5	GRASP_RAT	General receptor for phosphoinositides 1-associated scaffold protein	11850456	Tamalin, a PDZ domain-containing protein, links a protein complex formation of group 1 metabotropic glutamate receptors and the guanine nucleotide exchange factor cytohesins.

P97639	MCHR1_RAT	Melanin-concentrating hormone receptor 1	10559938	The receptor for the orexigenic peptide melanin-concentrating hormone is a G-protein-coupled receptor.

Q12745	SEC39_YEAST	Protein transport protein SEC39	15942868	Isolation of Saccharomyces cerevisiae RNase T1 hypersensitive (rns) mutants and genetic analysis of the RNS1/DSL1 gene.

O75663	TIPRL_HUMAN	TIP41-like protein	16085932	A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity.

O13696	IDH1_SCHPO	Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial	10975257	Isolation and RNA-binding analysis of NAD+ -isocitrate dehydrogenases from Kluyveromyces lactis and Schizosaccharomyces pombe.

O70441	SYN3_RAT	Synapsin-3	11867766	Neuronal nitric-oxide synthase localization mediated by a ternary complex with synapsin and CAPON.

Q9Y2S2	CRYL1_HUMAN	Lambda-crystallin homolog	15809331	Structural and functional chracterization of rabbit and human L- gulonate 3-dehydrogenase.

Q01475	SAR1_SCHPO	Small COPII coat GTPase sar1	11839792	Three proteins required for early steps in the protein secretory pathway also affect nuclear envelope structure and cell cycle progression in fission yeast.

Q9VDQ7	NAA25_DROME	Phagocyte signaling-impaired protein	17208189	Psidin is required in Drosophila blood cells for both phagocytic degradation and immune activation of the fat body.

P06239	LCK_HUMAN	Tyrosine-protein kinase Lck	8794306	Human immunodeficiency virus type 1 Nef binds directly to LCK and mitogen-activated protein kinase, inhibiting kinase activity.

P47176	BCA2_YEAST	Branched-chain-amino-acid aminotransferase, cytosolic	8798704	Mitochondrial and cytosolic branched-chain amino acid transaminases from yeast, homologs of the myc oncogene-regulated Eca39 protein.

Q3UPW2	ELF3_MOUSE	ETS-related transcription factor Elf-3	11984530	Inactivation of the transcription factor Elf3 in mice results in dysmorphogenesis and altered differentiation of intestinal epithelium.

P53214	MTL1_YEAST	Protein MTL1	15637049	Pkc1 and the upstream elements of the cell integrity pathway in Saccharomyces cerevisiae, Rom2 and Mtl1, are required for cellular responses to oxidative stress.

P34756	FAB1_YEAST	1-phosphatidylinositol-3-phosphate 5-kinase FAB1	11889142	Osmotic stress-induced increase of phosphatidylinositol 3,5- bisphosphate requires Vac14p, an activator of the lipid kinase Fab1p.

P28570	SC6A8_RAT	Sodium- and chloride-dependent creatine transporter 1	1633856	Primary structure and functional expression of a choline transporter expressed in the rat nervous system.

Q9H2A7	CXL16_HUMAN	C-X-C motif chemokine 16	11017100	A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo.

Q12393	GEP5_YEAST	Genetic interactor of prohibitin 5, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q28DH2	TBPL2_XENTR	TATA box-binding protein-like protein 2	17703192	TBP paralogs accommodate metazoan- and vertebrate-specific developmental gene regulation.

Q91V88	NPNT_MOUSE	Nephronectin	17537792	The ECM protein nephronectin promotes kidney development via integrin alpha8beta1-mediated stimulation of Gdnf expression.

Q04087	LRS4_YEAST	Monopolin complex subunit LRS4	12689592	Kinetochore recruitment of two nucleolar proteins is required for homolog segregation in meiosis I.

P61966	AP1S1_HUMAN	AP-1 complex subunit sigma-1A	9733768	Identification and characterization of novel clathrin adaptor-related proteins.

Q06096	COG4_YEAST	Conserved oligomeric Golgi complex subunit 4	11703943	The Sec34/35 Golgi transport complex is related to the exocyst, defining a family of complexes involved in multiple steps of membrane traffic.

O42766	1433_CANAL	14-3-3 protein homolog	11754483	The Candida albicans 14-3-3 gene, BMH1, is essential for growth.

P13382	DPOA_YEAST	DNA polymerase alpha catalytic subunit A	10898792	The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase alpha and the telomerase- associated est1 protein.

P28748	SPI1_SCHPO	GTP-binding nuclear protein spi1	1855255	Premature initiation of mitosis in yeast lacking RCC1 or an interacting GTPase.

P70232	CHL1_MOUSE	Neural cell adhesion molecule L1-like protein	15504324	Close homolog of L1 modulates area-specific neuronal positioning and dendrite orientation in the cerebral cortex.

P10646	TFPI1_HUMAN	Tissue factor pathway inhibitor	2271516	Regulation of coagulation by a multivalent Kunitz-type inhibitor.

Q99504	EYA3_HUMAN	Eyes absent homolog 3	9049631	Cloning and characterization of two vertebrate homologs of the Drosophila eyes absent gene.

O74947	YJBA_SCHPO	Uncharacterized protein C553.10	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O15127	SCAM2_HUMAN	Secretory carrier-associated membrane protein 2	15840657	Secretory carrier membrane proteins interact and regulate trafficking of the organellar (Na+,K+)/H+ exchanger NHE7.

P08708	RS17_HUMAN	40S ribosomal protein S17	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

P87174	DPB4_SCHPO	DNA polymerase epsilon subunit D	15388803	Identification and cloning of two putative subunits of DNA polymerase epsilon in fission yeast.

Q8BYH0	DRGX_MOUSE	Dorsal root ganglia homeobox protein	11498051	The paired homeodomain protein DRG11 is required for the projection of cutaneous sensory afferent fibers to the dorsal spinal cord.

P05067	A4_HUMAN	Amyloid beta A4 protein	19366692	BRI3 inhibits amyloid precursor protein processing in a mechanistically distinct manner from its homologue dementia gene BRI2.

Q9UKX2	MYH2_HUMAN	Myosin-2	10388558	Comparative sequence analysis of the complete human sarcomeric myosin heavy chain family: implications for functional diversity.

Q92583	CCL17_HUMAN	C-C motif chemokine 17	8702936	Molecular cloning of a novel T cell-directed CC chemokine expressed in thymus by signal sequence trap using Epstein-Barr virus vector.

Q61324	ARNT2_MOUSE	Aryl hydrocarbon receptor nuclear translocator 2	8657146	cDNA cloning and tissue-specific expression of a novel basic helix- loop-helix/PAS factor (Arnt2) with close sequence similarity to the aryl hydrocarbon receptor nuclear translocator (Arnt).

P42702	LIFR_HUMAN	Leukemia inhibitory factor receptor	1915266	Leukemia inhibitory factor receptor is structurally related to the IL-6 signal transducer, gp130.

P40491	FMC1_YEAST	ATP synthase assembly factor FMC1, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q9NZP2	OR6C2_HUMAN	Olfactory receptor 6C2	10706615	The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates.

P20020	AT2B1_HUMAN	Plasma membrane calcium-transporting ATPase 1	8396145	Structure of the gene encoding the human plasma membrane calcium pump isoform 1.

Q9ZVD0	SRRT_ARATH	Serrate RNA effector molecule	18550839	Dual roles of the nuclear cap-binding complex and SERRATE in pre-mRNA splicing and microRNA processing in Arabidopsis thaliana.

Q7Z6K1	THAP5_HUMAN	THAP domain-containing protein 5	19502560	THAP5 is a human cardiac-specific inhibitor of cell cycle that is cleaved by the proapoptotic Omi/HtrA2 protease during cell death.

Q13609	DNSL3_HUMAN	Deoxyribonuclease gamma	9205125	Identification, localization, and expression of two novel human genes similar to deoxyribonuclease I.

Q16655	MAR1_HUMAN	Melanoma antigen recognized by T-cells 1	12191019	The melanocytic protein Melan-A/MART-1 has a subcellular localization distinct from typical melanosomal proteins.

Q9Y2X8	UB2D4_HUMAN	Ubiquitin-conjugating enzyme E2 D4	20061386	The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.

Q498L9	KI15B_XENLA	Kinesin-like protein KIF15-B	8548825	Xklp2, a novel Xenopus centrosomal kinesin-like protein required for centrosome separation during mitosis.

A0MS83	ZN148_DANRE	Zinc finger protein 148	16914492	The transcription factor ZBP-89 controls generation of the hematopoietic lineage in zebrafish and mouse embryonic stem cells.

Q9CYB0	TRI13_MOUSE	E3 ubiquitin-protein ligase TRIM13	11331580	The tripartite motif family identifies cell compartments.

P46093	GPR4_HUMAN	G-protein coupled receptor 4	8595909	Isolation of a novel G protein-coupled receptor (GPR4) localized to chromosome 19q13.3.

Q0D840	TRXH1_ORYSJ	Thioredoxin H1	15618434	A novel cis-element that is responsive to oxidative stress regulates three antioxidant defense genes in rice.

Q14246	EMR1_HUMAN	EGF-like module-containing mucin-like hormone receptor-like 1	7601460	EMR1, an unusual member in the family of hormone receptors with seven transmembrane segments.

Q7TNJ2	ABCA7_RAT	ATP-binding cassette sub-family A member 7	12727224	Cloning of rat ABCA7 and its preferential expression in platelets.

O13829	RU17_SCHPO	U1 small nuclear ribonucleoprotein 70 kDa homolog	17264129	Proteomic analysis of the U1 snRNP of Schizosaccharomyces pombe reveals three essential organism-specific proteins.

P18206	VINC_HUMAN	Vinculin	18028034	Human alpha-synemin interacts directly with vinculin and metavinculin.

P49597	P2C56_ARATH	Protein phosphatase 2C 56	1834244	Cold acclimation and cold-regulated gene expression in ABA mutants of Arabidopsis thaliana.

Q76PD2	YJ01_SCHPO	LIM domain and RING finger protein C1223.01	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O94656	YGF5_SCHPO	Meiotic chromosome segregation protein C405.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8GWJ7	CRK19_ARATH	Cysteine-rich receptor-like protein kinase 19	15604743	Activation of hypersensitive cell death by pathogen-induced receptor- like protein kinases from Arabidopsis.

P0AD49	RAIA_ECOLI	Ribosome-associated inhibitor A	10535924	A protein residing at the subunit interface of the bacterial ribosome.

Q86IZ4	IPP2_DICDI	Protein phosphatase inhibitor 2	17336445	Identification and domain mapping of Dictyostelium discoideum type-1 protein phosphatase inhibitor-2.

P42345	MTOR_HUMAN	Serine/threonine-protein kinase mTOR	15467718	Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive.

P13056	NR2C1_HUMAN	Nuclear receptor subfamily 2 group C member 1	2597158	Molecular cloning of new human TR2 receptors: a class of steroid receptor with multiple ligand-binding domains.

P35193	ATG19_YEAST	Autophagy-related protein 19	12479807	Studies of cargo delivery to the vacuole mediated by autophagosomes in Saccharomyces cerevisiae.

Q08480	KAD2_ORYSJ	Adenylate kinase B	1302636	Molecular characterization of cDNA encoding for adenylate kinase of rice (Oryza sativa L.).

P40395	RIC1_YEAST	Protein RIC1	10990452	Ric1p and Rgp1p form a complex that catalyses nucleotide exchange on Ypt6p.

P62943	FKB1A_RABIT	Peptidyl-prolyl cis-trans isomerase FKBP1A	1374404	FK506 binding protein associated with the calcium release channel (ryanodine receptor).

Q05209	PTN12_HUMAN	Tyrosine-protein phosphatase non-receptor type 12	8454633	Cloning and expression of PTP-PEST. A novel, human, nontransmembrane protein tyrosine phosphatase.

Q91ZY8	TRIM9_RAT	E3 ubiquitin-protein ligase TRIM9	11524423	Spring, a novel RING finger protein that regulates synaptic vesicle exocytosis.

Q9EQ52	V1R48_MOUSE	Vomeronasal type-1 receptor 48	11116090	Sequence diversity and genomic organization of vomeronasal receptor genes in the mouse.

P08879	NDKA_DROME	Nucleoside diphosphate kinase	2175255	A Drosophila gene that is homologous to a mammalian gene associated with tumor metastasis codes for a nucleoside diphosphate kinase.

Q10426	RIK1_SCHPO	Chromatin modification-related protein rik1	10766735	Distinct protein interaction domains and protein spreading in a complex centromere.

Q5W670	IAA18_ORYSJ	Auxin-responsive protein IAA18	16200395	Structure and expression analysis of early auxin-responsive Aux/IAA gene family in rice (Oryza sativa).

Q99JB4	KRBBB_MOUSE	Killer cell lectin-like receptor subfamily B member 1B allele B	14990792	Missing self-recognition of Ocil/Clr-b by inhibitory NKR-P1 natural killer cell receptors.

Q9BLJ6	BAGS_BOMMO	BAG domain-containing protein Samui	11422373	Samui, a novel cold-inducible gene, encoding a protein with a BAG domain similar to silencer of death domains (SODD/BAG-4), isolated from Bombyx diapause eggs.

Q07699	SCN1B_HUMAN	Sodium channel subunit beta-1	8394762	The cloning and expression of a sodium channel beta 1-subunit cDNA from human brain.

P83688	CC12_EUGGR	Cytochrome b6/f complex 12.6 kDa peptide	12837550	Cytochrome f and subunit IV, two essential components of the photosynthetic bf complex typically encoded in the chloroplast genome, are nucleus-encoded in Euglena gracilis.

Q9Y2Z0	SUGT1_HUMAN	Suppressor of G2 allele of SKP1 homolog	10445024	SGT1 encodes an essential component of the yeast kinetochore assembly pathway and a novel subunit of the SCF ubiquitin ligase complex.

O14965	STK6_HUMAN	Serine/threonine-protein kinase 6	19801554	A cancer-associated aurora A mutant is mislocalized and misregulated due to loss of interaction with TPX2.

P15088	CBPA3_HUMAN	Mast cell carboxypeptidase A	1629626	Human skin mast cell carboxypeptidase: functional characterization, cDNA cloning, and genealogy.

P0C0V0	DEGP_ECOLI	Protease do	2180903	The HtrA (DegP) protein, essential for Escherichia coli survival at high temperatures, is an endopeptidase.

Q16539	MK14_HUMAN	Mitogen-activated protein kinase 14	10838079	Distinct carboxy-termini confer divergent characteristics to the mitogen-activated protein kinase p38alpha and its splice isoform Mxi2.

Q12872	SFRS8_HUMAN	Splicing factor, arginine/serine-rich 8	8940107	The mammalian homolog of suppressor-of-white-apricot regulates alternative mRNA splicing of CD45 exon 4 and fibronectin IIICS.

Q9U5L1	SRPR_DROME	Signal recognition particle receptor subunit alpha homolog	8360279	Characterization of a putative Drosophila GTP-binding protein.

Q7TQP3	GP119_MOUSE	Glucose-dependent insulinotropic receptor	15607732	Lysophosphatidylcholine enhances glucose-dependent insulin secretion via an orphan G-protein-coupled receptor.

Q9VMJ7	KDM5_DROME	Lysine-specific demethylase lid	17311883	The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth.

P01225	FSHB_HUMAN	Follitropin subunit beta	6774759	Studies on the disulfide bonds in human pituitary follicle- stimulating hormone.

P78972	SLP1_SCHPO	WD repeat-containing protein slp1	9461438	Fission yeast Slp1: an effector of the Mad2-dependent spindle checkpoint.

P84961	FXA2B_XENLA	Forkhead box protein A2-B	15656969	Of fox and frogs: fox (fork head/winged helix) transcription factors in Xenopus development.

P36955	PEDF_HUMAN	Pigment epithelium-derived factor	8226833	Overexpression of fetal human pigment epithelium-derived factor in Escherichia coli. A functionally active neurotrophic factor.

P41180	CASR_HUMAN	Extracellular calcium-sensing receptor	7916660	Mutations in the human Ca(2+)-sensing receptor gene cause familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism.

A7BHQ9	TYRO_PHONA	Tyrosinase	17617709	Purification, characterization, and molecular cloning of tyrosinase from Pholiota nameko.

P46663	BKRB1_HUMAN	B1 bradykinin receptor	8063797	Expression cloning of a human B1 bradykinin receptor.

Q08906	FIT2_YEAST	Facilitator of iron transport 2	10383953	Amino acid residues in the omega-minus region participate in cellular localization of yeast glycosylphosphatidylinositol-attached proteins.

P56589	PEX3_HUMAN	Peroxisomal biogenesis factor 3	15007061	PEX3 functions as a PEX19 docking factor in the import of class I peroxisomal membrane proteins.

P03994	HPLN1_RAT	Hyaluronan and proteoglycan link protein 1	3459153	Link protein cDNA sequence reveals a tandemly repeated protein structure.

Q94B74	NUDT2_ARATH	Nudix hydrolase 2	15878881	Comprehensive analysis of cytosolic nudix hydrolases in Arabidopsis thaliana.

P01625	KV402_HUMAN	Ig kappa chain V-IV region Len	50995	The primary structure of a monoclonic immunoglobulin-L-chain of subgroup IV of the kappa type (Bence-Jones protein Len).

P21399	ACOC_HUMAN	Cytoplasmic aconitate hydratase	1738601	Expression of active iron regulatory factor from a full-length human cDNA by in vitro transcription/translation.

P0A998	FTNA_ECOLI	Ferritin-1	8281950	Overproduction, purification and characterization of the Escherichia coli ferritin.

Q22289	TBX9_CAEEL	T-box transcription factor tbx-9	15066124	Caenorhabditis elegans T-box genes tbx-9 and tbx-8 are required for formation of hypodermis and body-wall muscle in embryogenesis.

Q5GF25	MANEA_RAT	Glycoprotein endo-alpha-1,2-mannosidase	9361017	Molecular cloning and expression of rat liver endo-alpha-mannosidase, an N-linked oligosaccharide processing enzyme.

P63007	LHX1_RAT	LIM/homeobox protein Lhx1	8793615	The LIM homeodomain protein Lim-1 is widely expressed in neural, neural crest and mesoderm derivatives in vertebrate development.

P51157	RAB28_HUMAN	Ras-related protein Rab-28	19026641	Large nucleotide-dependent conformational change in Rab28.

P43681	ACHA4_HUMAN	Neuronal acetylcholine receptor subunit alpha-4	14623738	A Korean kindred with autosomal dominant nocturnal frontal lobe epilepsy and mental retardation.

P0A9J0	RNG_ECOLI	Ribonuclease G	10362534	Escherichia coli cafA gene encodes a novel RNase, designated as RNase G, involved in processing of the 5' end of 16S rRNA.

O46339	HTH_DROME	Homeobox protein homothorax	9463350	Dorsotonals/homothorax, the Drosophila homologue of meis1, interacts with extradenticle in patterning of the embryonic PNS.

Q02928	CP4AB_HUMAN	Cytochrome P450 4A11	7679927	Characterization of a cDNA encoding a human kidney, cytochrome P-450 4A fatty acid omega-hydroxylase and the cognate enzyme expressed in Escherichia coli.

Q9R1A3	NET3_MOUSE	Netrin-3	10366627	Netrin-3, a mouse homolog of human NTN2L, is highly expressed in sensory ganglia and shows differential binding to netrin receptors.

Q27403	GCM_DROME	Transcription factor glial cells missing	7553844	Glial cells missing: a binary switch between neuronal and glial determination in Drosophila.

Q7YU29	DMDE_DROME	Dystrophin, isoform E	17355978	A putative Src homology 3 domain binding motif but not the C-terminal dystrophin WW domain binding motif is required for dystroglycan function in cellular polarity in Drosophila.

P63046	ST4A1_MOUSE	Sulfotransferase 4A1	12039030	Highly conserved mouse and human brain sulfotransferases: molecular cloning, expression, and functional characterization.

Q16401	PSMD5_HUMAN	26S proteasome non-ATPase regulatory subunit 5	19490896	Assembly pathway of the Mammalian proteasome base subcomplex is mediated by multiple specific chaperones.

P75728	UBIF_ECOLI	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase	10802164	Ubiquinone (coenzyme Q) biosynthesis in Escherichia coli: identification of the ubiF gene.

Q00604	NDP_HUMAN	Norrin	10484772	Coats' disease of the retina (unilateral retinal telangiectasis) caused by somatic mutation in the NDP gene: a role for norrin in retinal angiogenesis.

O15144	ARPC2_HUMAN	Actin-related protein 2/3 complex subunit 2	9230079	The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly.

O43422	P52K_HUMAN	52 kDa repressor of the inhibitor of the protein kinase	9447982	Regulation of interferon-induced protein kinase PKR: modulation of P58IPK inhibitory function by a novel protein, P52rIPK.

Q9BUE0	MED18_HUMAN	Mediator of RNA polymerase II transcription subunit 18	12584197	Identification of mammalian Mediator subunits with similarities to yeast Mediator subunits Srb5, Srb6, Med11, and Rox3.

Q08605	GAGA_DROME	Transcription factor GAGA	12771214	The Drosophila Corto protein interacts with Polycomb-group proteins and the GAGA factor.

P29037	TBP_MOUSE	TATA-box-binding protein	9524124	UTF1, a novel transcriptional coactivator expressed in pluripotent embryonic stem cells and extra-embryonic cells.

Q9USQ7	MUG71_SCHPO	Meiotically up-regulated gene 71 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P98088	MUC5A_HUMAN	Mucin-5AC	7513696	Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5).

Q9Z138	ROR2_MOUSE	Tyrosine-protein kinase transmembrane receptor ROR2	10700181	Ror2, encoding a receptor-like tyrosine kinase, is required for cartilage and growth plate development.

Q00657	CSPG4_RAT	Chondroitin sulfate proteoglycan 4	9099729	The membrane-spanning proteoglycan NG2 binds to collagens V and VI through the central nonglobular domain of its core protein.

Q9VZF4	FBXW7_DROME	F-box/WD repeat-containing protein 7	15175253	The mitotic-to-endocycle switch in Drosophila follicle cells is executed by Notch-dependent regulation of G1/S, G2/M and M/G1 cell- cycle transitions.

Q5RH95	RSAD2_DANRE	Radical S-adenosyl methionine domain-containing protein 2	17371995	Identification of the zebrafish IFN receptor: implications for the origin of the vertebrate IFN system.

Q93Y07	SFR2_ARATH	Beta-glucosidase-like SFR2, chloroplastic	18466306	A role for SENSITIVE TO FREEZING2 in protecting chloroplasts against freeze-induced damage in Arabidopsis.

P16581	LYAM2_HUMAN	E-selectin	2466335	Endothelial leukocyte adhesion molecule 1: an inducible receptor for neutrophils related to complement regulatory proteins and lectins.

Q9US04	GGT1_SCHPO	Gamma-glutamyltranspeptidase 1	15765057	The Schizosaccharomyces pombe gene encoding gamma-glutamyl transpeptidase I is regulated by non-fermentable carbon sources and nitrogen starvation.

P49736	MCM2_HUMAN	DNA replication licensing factor MCM2	8175912	A human nuclear protein with sequence homology to a family of early S phase proteins is required for entry into S phase and for cell division.

Q9VZW5	FMAR_DROME	FMRFamide receptor	12438685	Identification in Drosophila melanogaster of the invertebrate G protein-coupled FMRFamide receptor.

Q94KI8	TPC1_ARATH	Two pore calcium channel protein 1	17253984	A gain-of-function allele of TPC1 activates oxylipin biogenesis after leaf wounding in Arabidopsis.

P51582	P2RY4_HUMAN	P2Y purinoceptor 4	8537336	Cloning and functional expression of a human uridine nucleotide receptor.

Q867X6	CY24A_DICDI	Superoxide-generating NADPH oxidase light chain subunit	15950752	NADPH oxidase homologs are required for normal cell differentiation and morphogenesis in Dictyostelium discoideum.

P43561	FET5_YEAST	Iron transport multicopper oxidase FET5	9413439	The yeast FET5 gene encodes a FET3-related multicopper oxidase implicated in iron transport.

P76129	DOSP_ECOLI	Oxygen sensor protein DosP	10704219	Dos, a heme-binding PAS protein from Escherichia coli, is a direct oxygen sensor.

P78386	KRT85_HUMAN	Keratin, type II cuticular Hb5	9084137	Sequences and differential expression of three novel human type-II hair keratins.

P54763	EPHB2_MOUSE	Ephrin type-B receptor 2	9883737	PDZ proteins bind, cluster, and synaptically colocalize with Eph receptors and their ephrin ligands.

P61008	SPCS3_CANFA	Signal peptidase complex subunit 3	3511473	Purification of microsomal signal peptidase as a complex.

Q08822	ETFD_YEAST	Probable electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial	11502169	Yeast mitochondrial dehydrogenases are associated in a supramolecular complex.

Q05791	CD123_YEAST	Cell division cycle protein 123	14562095	Global analysis of protein localization in budding yeast.

Q16851	UGPA_HUMAN	UTP--glucose-1-phosphate uridylyltransferase	8354390	Cloning of a human liver UDP-glucose pyrophosphorylase cDNA by complementation of the bacterial galU mutation.

O75446	SAP30_HUMAN	Histone deacetylase complex subunit SAP30	12670868	Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell- proliferation factor HCF-1.

P38925	SMF1_YEAST	Manganese transporter SMF1	8643535	A yeast manganese transporter related to the macrophage protein involved in conferring resistance to mycobacteria.

P62247	RS8_DANRE	40S ribosomal protein S8	15138505	Many ribosomal protein genes are cancer genes in zebrafish.

P81117	NUCB2_MOUSE	Nucleobindin-2	10915798	The postmitotic growth suppressor necdin interacts with a calcium- binding protein (NEFA) in neuronal cytoplasm.

P46531	NOTC1_HUMAN	Neurogenic locus notch homolog protein 1	1831692	TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms.

P36967	SUCA_DICDI	Succinyl-CoA ligase [GDP-forming] subunit alpha, mitochondrial	8448193	P36, a Dictyostelium discoideum protein whose phosphorylation is stimulated by GDP, is homologous to the alpha-subunit of succinyl-CoA synthetase.

P20156	VGF_RAT	Neurosecretory protein VGF	2017159	Structure of the gene encoding VGF, a nervous system-specific mRNA that is rapidly and selectively induced by nerve growth factor in PC12 cells.

Q8LBW3	LBD12_ARATH	LOB domain-containing protein 12	12787254	Activation tagging, a novel tool to dissect the functions of a gene family.

P91938	TRXR1_DROME	Thioredoxin reductase 1, mitochondrial	11525742	Cooperative action of antioxidant defense systems in Drosophila.

O82794	AGL24_ARATH	MADS-box protein AGL24	14716314	Repression of AGAMOUS-LIKE 24 is a crucial step in promoting flower development.

Q16394	EXT1_HUMAN	Exostosin-1	7550340	Cloning of the putative tumour suppressor gene for hereditary multiple exostoses (EXT1).

Q71F54	SH3R1_RAT	Putative E3 ubiquitin-protein ligase SH3RF1	16230351	Siah1 interacts with the scaffold protein POSH to promote JNK activation and apoptosis.

P87231	MUS81_SCHPO	Crossover junction endonuclease mus81	11073977	Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1.

Q6E3K9	PRONF_PROFF	Propionicin-F	15574930	Molecular and genetic characterization of propionicin F, a bacteriocin from Propionibacterium freudenreichii.

Q9UBC5	MYO1A_HUMAN	Myosin-Ia	12736868	Multiple mutations of MYO1A, a cochlear-expressed gene, in sensorineural hearing loss.

Q96MH2	HEXI2_HUMAN	Protein HEXIM2	15713662	HEXIM2, a HEXIM1-related protein, regulates positive transcription elongation factor b through association with 7SK.

P38605	CAS1_ARATH	Cycloartenol synthase	7505443	Isolation of an Arabidopsis thaliana gene encoding cycloartenol synthase by functional expression in a yeast mutant lacking lanosterol synthase by the use of a chromatographic screen.

P18409	MDM10_YEAST	Mitochondrial distribution and morphology protein 10	13679517	A protein complex containing Mdm10p, Mdm12p, and Mmm1p links mitochondrial membranes and DNA to the cytoskeleton-based segregation machinery.

P09495	TPM4_RAT	Tropomyosin alpha-4 chain	2112608	Structure and complete nucleotide sequence of the gene encoding rat fibroblast tropomyosin 4.

Q8L4M1	DWA1_ARATH	WD repeat-containing protein DWA1	20525848	DWA1 and DWA2, two Arabidopsis DWD protein components of CUL4-based E3 ligases, act together as negative regulators in aba signal transduction.

Q9UUJ4	REC24_SCHPO	Meiotic recombination protein rec24	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

Q15464	SHB_HUMAN	SH2 domain-containing adapter protein B	8302579	Shb is a ubiquitously expressed Src homology 2 protein.

Q9LR64	Y1360_ARATH	Thylakoid lumenal protein At1g03610, chloroplastic	11826309	Central functions of the lumenal and peripheral thylakoid proteome of Arabidopsis determined by experimentation and genome-wide prediction.

P40059	DOT6_YEAST	Transcriptional regulatory protein DOT6	9755194	Identification of high-copy disruptors of telomeric silencing in Saccharomyces cerevisiae.

Q80Z64	NANOG_MOUSE	Homeobox protein NANOG	16518401	The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells.

Q99598	TSNAX_HUMAN	Translin-associated protein X	9013868	Isolation and characterization of a cDNA encoding a translin-like protein, TRAX.

Q01574	ACS1_YEAST	Acetyl-coenzyme A synthetase 1	1363452	Cloning and disruption of a gene required for growth on acetate but not on ethanol: the acetyl-coenzyme A synthetase gene of Saccharomyces cerevisiae.

P34160	NCBP1_YEAST	Nuclear cap-binding protein complex subunit 1	10072386	Identification of eight proteins that cross-link to pre-mRNA in the yeast commitment complex.

P32944	SWE1_YEAST	Mitosis inhibitor protein kinase SWE1	8930890	Cdc28 tyrosine phosphorylation and the morphogenesis checkpoint in budding yeast.

P36871	PGM1_HUMAN	Phosphoglucomutase-1	1530890	Phosphoglucomutase 1: complete human and rabbit mRNA sequences and direct mapping of this highly polymorphic marker on human chromosome 1.

P01825	HV207_HUMAN	Ig heavy chain V-II region NEWM	407927	Amino acid sequence of the VH region of a human myeloma immunoglobulin (IgG New).

Q9FQ08	KU70_ARATH	ATP-dependent DNA helicase 2 subunit KU70	18515112	Regulation of Arabidopsis thaliana Ku genes at different developmental stages under heat stress.

Q9JK79	CKLF_RAT	Chemokine-like factor	12706894	Molecular cloning and characterization of rat chemokine-like factor 1 and 2.

Q4G176	ACSF3_HUMAN	Acyl-CoA synthetase family member 3, mitochondrial	17762044	Evidence for 26 distinct acyl-coenzyme A synthetase genes in the human genome.

Q13363	CTBP1_HUMAN	C-terminal-binding protein 1	16609867	The FoxP subclass in Xenopus laevis development.

Q66K89	E4F1_HUMAN	Transcription factor E4F1	14729613	Identification of the E1A-regulated transcription factor p120 E4F as an interacting partner of the RASSF1A candidate tumor suppressor gene.

Q9YHZ6	CDC45_XENLA	Cell division control protein 45 homolog	12730133	A novel ring-like complex of Xenopus proteins essential for the initiation of DNA replication.

Q9BTU6	P4K2A_HUMAN	Phosphatidylinositol 4-kinase type 2-alpha	11279162	Cloning of a human type II phosphatidylinositol 4-kinase reveals a novel lipid kinase family.

O60232	SSA27_HUMAN	Sjoegren syndrome/scleroderma autoantigen 1	9486406	cDNA cloning of a novel autoantigen targeted by a minor subset of anti-centromere antibodies.

P21965	MCK1_YEAST	Protein kinase MCK1	2010084	A suppressor of a centromere DNA mutation encodes a putative protein kinase (MCK1).

P08697	A2AP_HUMAN	Alpha-2-antiplasmin	2433286	Primary structure of human alpha 2-antiplasmin, a serine protease inhibitor (serpin).

Q11206	SIA4C_HUMAN	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4	8557707	Genomic organization and chromosomal mapping of the Gal beta 1,3GalNAc/Gal beta 1,4GlcNAc alpha 2,3-sialyltransferase.

P52951	GBX2_HUMAN	Homeobox protein GBX-2	8838315	Characterization and sequence analysis of the human homeobox- containing gene GBX2.

O95257	GA45G_HUMAN	Growth arrest and DNA damage-inducible protein GADD45 gamma	9827804	A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK.

Q09188	ADT_SCHPO	ADP,ATP carrier protein	8675018	Cloning of the gene encoding the mitochondrial adenine nucleotide carrier of Schizosaccharomyces pombe by functional complementation in Saccharomyces cerevisiae.

Q9H3D4	P63_HUMAN	Tumor protein 63	9774969	p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities.

Q12149	RRP6_YEAST	Exosome complex exonuclease RRP6	10611239	A nuclear 3'-5' exonuclease involved in mRNA degradation interacts with Poly(A) polymerase and the hnRNA protein Npl3p.

P07476	INVO_HUMAN	Involucrin	1601889	Biophysical characterization of involucrin reveals a molecule ideally suited to function as an intermolecular cross-bridge of the keratinocyte cornified envelope.

P39692	MET10_YEAST	Sulfite reductase [NADPH] flavoprotein component	6751400	Studies on yeast sulfite reductase. IV. Structure and steady-state kinetics.

P05112	IL4_HUMAN	Interleukin-4	3016727	Isolation and characterization of a human interleukin cDNA clone, homologous to mouse B-cell stimulatory factor 1, that expresses B- cell- and T-cell-stimulating activities.

Q9UBE0	SAE1_HUMAN	SUMO-activating enzyme subunit 1	10187858	Identification of the enzyme required for activation of the small ubiquitin-like protein SUMO-1.

Q9FT70	RQL4B_ARATH	ATP-dependent DNA helicase Q-like 4B	12856935	Arabidopsis RecQsim, a plant-specific member of the RecQ helicase family, can suppress the MMS hypersensitivity of the yeast sgs1 mutant.

P35169	TOR1_YEAST	Serine/threonine-protein kinase TOR1	8741837	TOR controls translation initiation and early G1 progression in yeast.

O54836	ZMAT3_MOUSE	Zinc finger matrin-type protein 3	12135743	Identification of functional p53-binding motifs in the mouse wig-1 promoter.

Q95QW4	CDF1_CAEEL	Cation diffusion facilitator family protein 1	12015965	Zinc ions and cation diffusion facilitator proteins regulate Ras- mediated signaling.

Q9V5N8	STAN_DROME	Protocadherin-like wing polarity protein stan	10556066	The Drosophila tissue polarity gene starry night encodes a member of the protocadherin family.

P58200	VTI1B_RAT	Vesicle transport through interaction with t-SNAREs homolog 1B	15133481	Combinatorial SNARE complexes with VAMP7 or VAMP8 define different late endocytic fusion events.

P53187	HOP2_YEAST	Homologous-pairing protein 2	11940665	The Mnd1 protein forms a complex with Hop2 to promote homologous chromosome pairing and meiotic double-strand break repair.

P36600	KAPR_SCHPO	cAMP-dependent protein kinase regulatory subunit	1657594	Interaction between ran1+ protein kinase and cAMP dependent protein kinase as negative regulators of fission yeast meiosis.

P00493	HPRT_MOUSE	Hypoxanthine-guanine phosphoribosyltransferase	6326107	Structure, expression, and mutation of the hypoxanthine phosphoribosyltransferase gene.

P06213	INSR_HUMAN	Insulin receptor	8452530	Purified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinity.

P12980	LYL1_HUMAN	Protein lyl-1	2752424	lyl-1, a novel gene altered by chromosomal translocation in T cell leukemia, codes for a protein with a helix-loop-helix DNA binding motif.

Q9UKT5	FBX4_HUMAN	F-box only protein 4	16275645	The F-box protein FBX4 targets PIN2/TRF1 for ubiquitin-mediated degradation and regulates telomere maintenance.

Q12050	ELG1_YEAST	Telomere length regulation protein ELG1	14562095	Global analysis of protein localization in budding yeast.

P55107	BMP3B_HUMAN	Bone morphogenetic protein 3B	8670277	cDNA cloning and genomic structure of human bone morphogenetic protein-3B (BMP-3b).

Q9GPM4	PGK_DICDI	Phosphoglycerate kinase	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q92989	CLP1_HUMAN	Polyribonucleotide 5'-hydroxyl-kinase Clp1	17495927	The human RNA kinase hClp1 is active on 3' transfer RNA exons and short interfering RNAs.

O95260	ATE1_HUMAN	Arginyl-tRNA--protein transferase 1	9858543	Alternative splicing results in differential expression, activity, and localization of the two forms of arginyl-tRNA-protein transferase, a component of the N-end rule pathway.

Q15262	PTPRK_HUMAN	Receptor-type tyrosine-protein phosphatase kappa	9047348	Molecular cloning and chromosomal localization of a human gene homologous to the murine R-PTP-kappa, a receptor-type protein tyrosine phosphatase.

Q9V3I5	JIL1_DROME	Chromosomal serine/threonine-protein kinase JIL-1	14668387	Genetic and phenotypic analysis of alleles of the Drosophila chromosomal JIL-1 kinase reveals a functional requirement at multiple developmental stages.

Q8T390	SH3G3_DROME	Endophilin-A	11927550	Essential role of endophilin A in synaptic vesicle budding at the Drosophila neuromuscular junction.

Q8BI72	CARF_MOUSE	CDKN2A-interacting protein	12581788	A novel putative collaborator of p19ARF.

P22579	SIN3_YEAST	Transcriptional regulatory protein SIN3	14737171	The MAPK Hog1 recruits Rpd3 histone deacetylase to activate osmoresponsive genes.

P51638	CAV3_RAT	Caveolin-3	8567687	Molecular cloning of caveolin-3, a novel member of the caveolin gene family expressed predominantly in muscle.

Q9QZR8	PDZD2_RAT	PDZ domain-containing protein 2	10896674	A novel multiple PSD-95/Dlg-A/ZO-1 protein interacting with neural plakophilin-related armadillo repeat protein/delta-catenin and p0071.

P52815	RM12_HUMAN	39S ribosomal protein L12, mitochondrial	8626705	A delayed-early response nuclear gene encoding MRPL12, the mitochondrial homologue to the bacterial translational regulator L7/L12 protein.

P08243	ASNS_HUMAN	Asparagine synthetase [glutamine-hydrolyzing]	2564390	Expression of human asparagine synthetase in Escherichia coli.

Q09858	NNF1_SCHPO	Kinetochore protein nnf1	16079914	Molecular analysis of kinetochore architecture in fission yeast.

Q39026	MPK6_ARATH	Mitogen-activated protein kinase 6	12628921	A MAPK pathway mediates ethylene signaling in plants.

Q9BLG4	AMT1_DICDI	Ammonium transporter 1	16835443	Function of ammonium transporter A in the initiation of culmination of development in Dictyostelium discoideum.

Q9NHC3	CED2_CAEEL	Cell death abnormality protein 2	19402756	Abl kinase inhibits the engulfment of apopotic cells in Caenorhabditis elegans.

Q8R5M8	CADM1_MOUSE	Cell adhesion molecule 1	15707673	Distribution of RA175/TSLC1/SynCAM, a member of the immunoglobulin superfamily, in the developing nervous system.

Q7TSF0	DSG1C_MOUSE	Desmoglein-1-gamma	12631243	A novel mouse desmosomal cadherin family member, desmoglein 1 gamma.

P35247	SFTPD_HUMAN	Pulmonary surfactant-associated protein D	1339284	Purification, characterization and cDNA cloning of human lung surfactant protein D.

P51774	EGR2_RAT	Early growth response protein 2	8619872	mRNA differential display reveals Krox-20 as a neural plasticity- regulated gene in the rat hippocampus.

Q9LTB2	MMT1_ARATH	Methionine S-methyltransferase	12692340	Insertional inactivation of the methionine s-methyltransferase gene eliminates the s-methylmethionine cycle and increases the methylation ratio.

Q01292	ILV5_SPIOL	Ketol-acid reductoisomerase, chloroplastic	10739911	Structure of spinach acetohydroxyacid isomeroreductase complexed with its reaction product dihydroxymethylvalerate, manganese and (phospho)- ADP-ribose.

Q03525	TMA23_YEAST	Protein TMA23	17425675	Mutations in the nucleolar proteins Tma23 and Nop6 suppress the malfunction of the Nep1 protein.

Q8WVJ9	TWST2_HUMAN	Twist-related protein 2	11062344	Human Dermo-1 has attributes similar to twist in early bone development.

Q4JIM5	ABL2_MOUSE	Tyrosine-protein kinase ABL2	12748290	Two distinct phosphorylation pathways have additive effects on Abl family kinase activation.

P28829	BYR2_SCHPO	Protein kinase byr2	11709168	The Ras-Byr2RBD complex: structural basis for Ras effector recognition in yeast.

Q13625	ASPP2_HUMAN	Apoptosis-stimulating of p53 protein 2	8875926	Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2.

O42648	YF98_SCHPO	HMG box-containing protein C10F6.08c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8GRX1	BGL34_ARATH	Myrosinase 4	19703694	Myrosinases from root and leaves of Arabidopsis thaliana have different catalytic properties.

Q5AZ85	RGLB_EMENI	Rhamnogalacturonate lyase B	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

Q9FLU1	BIN4_ARATH	DNA-binding protein BIN4	17951446	MIDGET unravels functions of the Arabidopsis topoisomerase VI complex in DNA endoreduplication, chromatin condensation, and transcriptional silencing.

Q61062	DVL3_MOUSE	Segment polarity protein dishevelled homolog DVL-3	15456783	Independent mutations in mouse Vangl2 that cause neural tube defects in looptail mice impair interaction with members of the Dishevelled family.

Q10360	RRN10_SCHPO	RNA polymerase I-specific transcription initiation factor rrn10	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8VZ80	PLT5_ARATH	Polyol transporter 5	15598803	Arabidopsis POLYOL TRANSPORTER5, a new member of the monosaccharide transporter-like superfamily, mediates H+-symport of numerous substrates, including myo-inositol, glycerol, and ribose.

P53805	RCAN1_HUMAN	Calcipressin-1	8595418	A new human gene from the Down syndrome critical region encodes a proline-rich protein highly expressed in fetal brain and heart.

P70331	MDFI_MOUSE	MyoD family inhibitor	12192039	I-mfa domain proteins interact with Axin and affect its regulation of the Wnt and c-Jun N-terminal kinase signaling pathways.

Q8CFI0	NED4L_MOUSE	E3 ubiquitin-protein ligase NEDD4-like	11149908	A novel mouse Nedd4 protein suppresses the activity of the epithelial Na+ channel.

Q8NCD3	HJURP_HUMAN	Holliday junction recognition protein	19410544	Centromere-specific assembly of CENP-A nucleosomes is mediated by HJURP.

P02708	ACHA_HUMAN	Acetylcholine receptor subunit alpha	7619526	Mutation of the acetylcholine receptor alpha subunit causes a slow- channel myasthenic syndrome by enhancing agonist binding affinity.

P19021	AMD_HUMAN	Peptidyl-glycine alpha-amidating monooxygenase	2357221	Human peptidylglycine alpha-amidating monooxygenase: cDNA, cloning and functional expression of a truncated form in COS cells.

Q9P7X6	PSF1_SCHPO	DNA replication complex GINS protein psf1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8VI04	ASGL1_RAT	L-asparaginase	11984834	A novel asparaginase-like protein is a sperm autoantigen in rats.

Q6VV64	KCNKI_MOUSE	Potassium channel subfamily K member 18	14981085	The two-pore domain K+ channel, TRESK, is activated by the cytoplasmic calcium signal through calcineurin.

Q9R0L7	AKP8L_MOUSE	A-kinase anchor protein 8-like	16391387	Interaction of the nuclear matrix protein NAKAP with HypA and huntingtin: implications for nuclear toxicity in Huntington's disease pathogenesis.

Q10953	WRM1_CAEEL	Armadillo repeat-containing protein wrm-1	15572126	Multiple Wnt signaling pathways converge to orient the mitotic spindle in early C. elegans embryos.

Q64105	SPRE_MOUSE	Sepiapterin reductase	9405351	The 1.25-A crystal structure of sepiapterin reductase reveals its binding mode to pterins and brain neurotransmitters.

Q04827	CCND2_RAT	G1/S-specific cyclin-D2	8502486	The Vin-1 gene, identified by provirus insertional mutagenesis, is the cyclin D2.

P01375	TNFA_HUMAN	Tumor necrosis factor	3932069	Molecular cloning and expression of human tumor necrosis factor and comparison with mouse tumor necrosis factor.

P57727	TMPS3_HUMAN	Transmembrane protease serine 3	11068177	Ovarian tumor cells express a novel multi-domain cell surface serine protease.

P19087	GNAT2_HUMAN	Guanine nucleotide-binding protein G(t) subunit alpha-2	1936270	Molecular cloning and sequence analysis of cDNA and genomic DNA for the human cone transducin alpha subunit.

Q09591	MIX1_CAEEL	Mitotic chromosome and X-chromosome-associated protein mix-1	9458050	MIX-1: an essential component of the C. elegans mitotic machinery executes X chromosome dosage compensation.

Q9H0N0	RAB6C_HUMAN	Ras-related protein Rab-6C	11054569	Rab6c, a new member of the Rab gene family, is involved in drug resistance in MCF7/AdrR cells.

O00391	QSOX1_HUMAN	Sulfhydryl oxidase 1	17331072	Intracellular catalysis of disulfide bond formation by the human sulfhydryl oxidase, QSOX1.

Q13535	ATR_HUMAN	Serine/threonine-protein kinase ATR	8610130	cDNA cloning and gene mapping of a candidate human cell cycle checkpoint protein.

P18165	LORI_MOUSE	Loricrin	2190691	Identification of a major keratinocyte cell envelope protein, loricrin.

Q8VH51	RBM39_MOUSE	RNA-binding protein 39	11704680	Molecular cloning and characterization of CAPER, a novel coactivator of activating protein-1 and estrogen receptors.

Q9VTK2	POMT1_DROME	Protein O-mannosyltransferase 1	8650217	Mutations in the rotated abdomen locus affect muscle development and reveal an intrinsic asymmetry in Drosophila.

Q9JM54	APR_MOUSE	Phorbol-12-myristate-13-acetate-induced protein 1	10807576	Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis.

Q8UWJ4	DLLD_DANRE	Delta-like protein D	15013799	Three modules of zebrafish Mind bomb work cooperatively to promote Delta ubiquitination and endocytosis.

P0ABZ6	SURA_ECOLI	Chaperone surA	8626309	SurA assists the folding of Escherichia coli outer membrane proteins.

Q965Q4	SMS3_CAEEL	Putative phosphatidylcholine:ceramide cholinephosphotransferase 3	14685263	Identification of a family of animal sphingomyelin synthases.

Q12702	2ABA_SCHPO	Protein phosphatase PP2A regulatory subunit B	9078365	The regulatory subunits of fission yeast protein phosphatase 2A (PP2A) affect cell morphogenesis, cell wall synthesis and cytokinesis.

P53146	USE1_YEAST	Protein transport protein USE1	12893879	A SNARE required for retrograde transport to the endoplasmic reticulum.

P97953	VEGFC_MOUSE	Vascular endothelial growth factor C	9247316	Characterization of murine Flt4 ligand/VEGF-C.

Q62950	DPYL1_RAT	Dihydropyrimidinase-related protein 1	8815901	A family of rat CRMP genes is differentially expressed in the nervous system.

Q96DE5	APC16_HUMAN	Anaphase-promoting complex subunit 16	20360068	Systematic analysis of human protein complexes identifies chromosome segregation proteins.

Q9NWV8	MRI40_HUMAN	BRCA1-A complex subunit MERIT40	19261749	NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control.

O14368	HSP16_SCHPO	Heat shock protein 16	11452028	Expression of hsp16 in response to nucleotide depletion is regulated via the spc1 MAPK pathway in Schizosaccharomyces pombe.

Q16643	DREB_HUMAN	Drebrin	8216329	Molecular cloning of cDNA encoding human drebrin E and chromosomal mapping of its gene.

P30038	AL4A1_HUMAN	Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial	8621661	Cloning, characterization, and expression of cDNAs encoding human delta 1-pyrroline-5-carboxylate dehydrogenase.

O75340	PDCD6_HUMAN	Programmed cell death protein 6	19520058	Penta-EF-hand protein ALG-2 functions as a Ca2+-dependent adaptor that bridges Alix and TSG101.

P41932	14331_CAEEL	14-3-3-like protein 1	16777605	C. elegans SIR-2.1 interacts with 14-3-3 proteins to activate DAF-16 and extend life span.

P48582	BRO1_YEAST	Vacuolar-sorting protein BRO1	15326198	Bro1 coordinates deubiquitination in the multivesicular body pathway by recruiting Doa4 to endosomes.

Q9UTN7	MUG95_SCHPO	Meiotically up-regulated gene 95 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P54868	HMCS2_HUMAN	Hydroxymethylglutaryl-CoA synthase, mitochondrial	7851882	Human mitochondrial HMG CoA synthase: liver cDNA and partial genomic cloning, chromosome mapping to 1p12-p13, and possible role in vertebrate evolution.

Q9GU68	IF5A_DROME	Eukaryotic translation initiation factor 5A	19546244	The Drosophila deoxyhypusine hydroxylase homologue nero and its target eIF5A are required for cell growth and the regulation of autophagy.

O14222	FSV1_SCHPO	Syntaxin-like protein fsv1	14575697	Identification of a SNARE protein required for vacuolar protein transport in Schizosaccharomyces pombe.

Q99578	RIT2_HUMAN	GTP-binding protein Rit2	8918462	RIC, a calmodulin-binding Ras-like GTPase.

Q03750	TAF8_YEAST	Transcription initiation factor TFIID subunit 8	12138208	Molecular characterization of Saccharomyces cerevisiae TFIID.

O74778	BTB2_SCHPO	BTB/POZ domain-containing protein 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UBB5	MBD2_HUMAN	Methyl-CpG-binding domain protein 2	12183469	Two highly related p66 proteins comprise a new family of potent transcriptional repressors interacting with MBD2 and MBD3.

Q9XIC7	SERK2_ARATH	Somatic embryogenesis receptor kinase 2	16284306	Arabidopsis SOMATIC EMBRYOGENESIS RECEPTOR KINASES1 and 2 are essential for tapetum development and microspore maturation.

P97298	PEDF_MOUSE	Pigment epithelium-derived factor	12632345	Wilms' tumor growth is suppressed by antiangiogenic pigment epithelium-derived factor in a xenograft model.

Q9JIP0	TRPV5_RAT	Transient receptor potential cation channel subfamily V member 5	10875938	A rat kidney-specific calcium transporter in the distal nephron.

O22446	HDA19_ARATH	Histone deacetylase 19	11134508	Blocking histone deacetylation in Arabidopsis induces pleiotropic effects on plant gene regulation and development.

Q55E72	PKS1_DICDI	Probable polyketide synthase 1	16906151	Biosynthesis of Dictyostelium discoideum differentiation-inducing factor by a hybrid type I fatty acid-type III polyketide synthase.

Q9NI62	CYPE_DICDI	Peptidyl-prolyl cis-trans isomerase cypE	11690648	Cyclophilins of a novel subfamily interact with SNW/SKIP coregulator in Dictyostelium discoideum and Schizosaccharomyces pombe.

P35716	SOX11_HUMAN	Transcription factor SOX-11	8666406	The human SOX11 gene: cloning, chromosomal assignment and tissue expression.

Q9Y4K3	TRAF6_HUMAN	TNF receptor-associated factor 6	12721283	TIRP, a novel Toll/interleukin-1 receptor (TIR) domain-containing adapter protein involved in TIR signaling.

P91349	SPD5_CAEEL	Spindle-defective protein 5	12431374	Centrosome maturation and mitotic spindle assembly in C. elegans require SPD-5, a protein with multiple coiled-coil domains.

P26012	ITB8_HUMAN	Integrin beta-8	1918072	Cloning and expression of a divergent integrin subunit beta 8.

O22850	GPX3_ARATH	Probable glutathione peroxidase 3, mitochondrial	16998070	An Arabidopsis glutathione peroxidase functions as both a redox transducer and a scavenger in abscisic acid and drought stress responses.

P32069	TRPX_ARATH	Anthranilate synthase component I-2, chloroplastic	1392592	Two anthranilate synthase genes in Arabidopsis: defense-related regulation of the tryptophan pathway.

Q8H7F6	GRS16_ARATH	Monothiol glutaredoxin-S16, chloroplastic	12480930	Cloning and characterization of CXIP1 A novel PICOT domain-containing Arabidopsis protein that associates with CAX1.

Q15942	ZYX_HUMAN	Zyxin	8940160	Molecular characterization of human zyxin.

Q13107	UBP4_HUMAN	Ubiquitin carboxyl-terminal hydrolase 4	16316627	Oncogenic protein UnpEL/Usp4 deubiquitinates Ro52 by its isopeptidase activity.

Q9UTC4	YIDF_SCHPO	Uncharacterized protein C227.15	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q4KSH7	MP2K7_RAT	Dual specificity mitogen-activated protein kinase kinase 7	10051439	Stress- and cell type-dependent regulation of transfected c-Jun N- terminal kinase and mitogen-activated protein kinase kinase isoforms.

Q9VF87	CYFIP_DROME	Cytoplasmic FMR1-interacting protein	12818175	CYFIP/Sra-1 controls neuronal connectivity in Drosophila and links the Rac1 GTPase pathway to the fragile X protein.

O96690	PDF_DROME	Protein PDF	10619432	A pdf neuropeptide gene mutation and ablation of PDF neurons each cause severe abnormalities of behavioral circadian rhythms in Drosophila.

O95989	NUDT3_HUMAN	Diphosphoinositol polyphosphate phosphohydrolase 1	10419486	The diadenosine hexaphosphate hydrolases from Schizosaccharomyces pombe and Saccharomyces cerevisiae are homologues of the human diphosphoinositol polyphosphate phosphohydrolase. Overlapping substrate specificities in a MutT-type protein.

Q9V4Q0	GR43B_DROME	Putative chemosensory receptor 43b	14608037	Molecular evolution of the insect chemoreceptor gene superfamily in Drosophila melanogaster.

Q9HGL1	YHLB_SCHPO	Uncharacterized protein C800.11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q86UW1	OSTA_HUMAN	Organic solute transporter subunit alpha	16317684	OSTalpha-OSTbeta: a major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia.

Q16665	HIF1A_HUMAN	Hypoxia-inducible factor 1-alpha	12446723	Structure of factor-inhibiting hypoxia-inducible factor (HIF) reveals mechanism of oxidative modification of HIF-1 alpha.

P62841	RS15_HUMAN	40S ribosomal protein S15	2821540	Evolutionary conservation of the insulinoma gene rig and its possible function.

P28321	YJU3_YEAST	Serine hydrolase YJU3	16407407	Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins.

P40314	NACB2_YEAST	Nascent polypeptide-associated complex subunit beta-2	10219998	Initial characterization of the nascent polypeptide-associated complex in yeast.

Q8BGT0	OSTM1_MOUSE	Osteopetrosis-associated transmembrane protein 1	12627228	Grey-lethal mutation induces severe malignant autosomal recessive osteopetrosis in mouse and human.

Q969G3	SMCE1_HUMAN	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1	12917342	BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation.

P53632	PAP2_YEAST	Poly(A) RNA polymerase protein 2	15828860	A new yeast poly(A) polymerase complex involved in RNA quality control.

Q04235	TYW2_YEAST	tRNA wybutosine-synthesizing protein 2	16642040	Biosynthesis of wybutosine, a hyper-modified nucleoside in eukaryotic phenylalanine tRNA.

Q9VXB3	SAP30_DROME	Histone deacetylase complex subunit SAP30 homolog	12077326	The SIN3/RPD3 deacetylase complex is essential for G(2) phase cell cycle progression and regulation of SMRTER corepressor levels.

Q9Y7S5	YQO6_SCHPO	Uncharacterized membrane protein C569.06	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q96FC9	DDX11_HUMAN	Probable ATP-dependent RNA helicase DDX11	9013641	Characterization of putative human homologues of the yeast chromosome transmission fidelity gene, CHL1.

Q9NY72	SCN3B_HUMAN	Sodium channel subunit beta-3	10688874	Beta3: an additional auxiliary subunit of the voltage-sensitive sodium channel that modulates channel gating with distinct kinetics.

O14361	PHA2_SCHPO	Putative prephenate dehydratase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P16035	TIMP2_HUMAN	Metalloproteinase inhibitor 2	8810321	Structure and characterization of the human tissue inhibitor of metalloproteinases-2 gene.

Q13257	MD2L1_HUMAN	Mitotic spindle assembly checkpoint protein MAD2A	8824189	Identification of a human mitotic checkpoint gene: hsMAD2.

O95475	SIX6_HUMAN	Homeobox protein SIX6	10512683	Genomic cloning and characterization of the human homeobox gene SIX6 reveals a cluster of SIX genes in chromosome 14 and associates SIX6 hemizygosity with bilateral anophthalmia and pituitary anomalies.

Q8UVJ6	VANG2_DANRE	Vang-like protein 2	12874125	Prickle 1 regulates cell movements during gastrulation and neuronal migration in zebrafish.

Q8NFH8	REPS2_HUMAN	RalBP1-associated Eps domain-containing protein 2	9422736	Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of Ral.

Q12509	ARP6_YEAST	Actin-like protein ARP6	14690608	A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1.

Q12436	ZRT2_YEAST	Zinc-regulated transporter 2	8798516	The ZRT2 gene encodes the low affinity zinc transporter in Saccharomyces cerevisiae.

Q62431	ARI3A_MOUSE	AT-rich interactive domain-containing protein 3A	15456761	Mutations in the DNA-binding domain of the transcription factor Bright act as dominant negative proteins and interfere with immunoglobulin transactivation.

P08572	CO4A2_HUMAN	Collagen alpha-2(IV) chain	3345760	Human basement membrane collagen (type IV). The amino acid sequence of the alpha 2(IV) chain and its comparison with the alpha 1(IV) chain reveals deletions in the alpha 1(IV) chain.

P25888	RHLE_ECOLI	ATP-dependent RNA helicase rhlE	15196029	Studies on three E. coli DEAD-box helicases point to an unwinding mechanism different from that of model DNA helicases.

Q92922	SMRC1_HUMAN	SWI/SNF complex subunit SMARCC1	12917342	BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation.

Q9UTA8	YL8A_SCHPO	Uncharacterized methyltransferase-like C25B8.10	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q07478	SUB2_YEAST	ATP-dependent RNA helicase SUB2	11675790	Splicing factor Sub2p is required for nuclear mRNA export through its interaction with Yra1p.

P19838	NFKB1_HUMAN	Nuclear factor NF-kappa-B p105 subunit	14743216	A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.

P56522	ADRO_RAT	NADPH:adrenodoxin oxidoreductase, mitochondrial	10525147	cDNA cloning, overproduction and characterization of rat adrenodoxin reductase.

P34707	SKN1_CAEEL	Protein skinhead-1	1547503	skn-1, a maternally expressed gene required to specify the fate of ventral blastomeres in the early C. elegans embryo.

Q9ST27	PHOT2_ORYSJ	Phototropin-2	12068117	Photochemical properties of the flavin mononucleotide-binding domains of the phototropins from Arabidopsis, rice, and Chlamydomonas reinhardtii.

P40416	ATM1_YEAST	Iron-sulfur clusters transporter ATM1, mitochondrial	9428742	The ABC transporter Atm1p is required for mitochondrial iron homeostasis.

P84822	TY4_ASCTR	Tryptophyllin-4	15922344	Bradykinin-related peptides and tryptophyllins in the skin secretions of the most primitive extant frog, Ascaphus truei.

P41597	CCR2_HUMAN	C-C chemokine receptor type 2	8146186	Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tails.

Q42586	PYR5_ARATH	Uridine 5'-monophosphate synthase	8041358	Heterospecific cloning of Arabidopsis thaliana cDNAs by direct complementation of pyrimidine auxotrophic mutants of Saccharomyces cerevisiae. I. Cloning and sequence analysis of two cDNAs catalysing the second, fifth and sixth steps of the de novo pyrimidine biosynthesis pathway.

P63171	DYLT1_BOVIN	Dynein light chain Tctex-type 1	11425878	Cytoplasmic dynein regulation by subunit heterogeneity and its role in apical transport.

Q06187	BTK_HUMAN	Tyrosine-protein kinase BTK	9571151	Identification and characterization of a novel SH3-domain binding protein, Sab, which preferentially associates with Bruton's tyrosine kinase (Btk).

Q93575	RTEL1_CAEEL	Regulator of telomere elongation helicase 1 homolog	18957201	RTEL1 maintains genomic stability by suppressing homologous recombination.

Q9JHI8	NOX4_MOUSE	NADPH oxidase 4	10869423	Identification of renox, an NAD(P)H oxidase in kidney.

P91664	MAX_DROME	Protein max	8929412	Myc and Max homologs in Drosophila.

O00629	IMA4_HUMAN	Importin subunit alpha-4	9395085	Cloning of two novel human importin-alpha subunits and analysis of the expression pattern of the importin-alpha protein family.

P31750	AKT1_MOUSE	RAC-alpha serine/threonine-protein kinase	15722337	Phosphorylation of grb10 regulates its interaction with 14-3-3.

Q9Y6K9	NEMO_HUMAN	NF-kappa-B essential modulator	9751060	IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex.

P52286	SKP1_YEAST	Suppressor of kinetochore protein 1	10637232	Feedback-regulated degradation of the transcriptional activator Met4 is triggered by the SCF(Met30) complex.

P34252	SLD2_YEAST	DNA replication regulator SLD2	10097122	DRC1, DNA replication and checkpoint protein 1, functions with DPB11 to control DNA replication and the S-phase checkpoint in Saccharomyces cerevisiae.

Q9S9M2	WAKLD_ARATH	Wall-associated receptor kinase-like 4	16286448	Involvement of a cell wall-associated kinase, WAKL4, in Arabidopsis mineral responses.

O13792	SUB2_SCHPO	ATP-dependent RNA helicase uap56	11156603	Multiple roles for the yeast SUB2/yUAP56 gene in splicing.

P25854	CALM1_ARATH	Calmodulin-1/4	8507825	Calmodulin isoforms in Arabidopsis encoded by multiple divergent mRNAs.

P32578	SIP1_YEAST	SNF1 protein kinase subunit beta-1	7813428	A family of proteins containing a conserved domain that mediates interaction with the yeast SNF1 protein kinase complex.

Q02685	RMI1_YEAST	RecQ-mediated genome instability protein 1	15899853	Yeast Rmi1/Nce4 controls genome stability as a subunit of the Sgs1- Top3 complex.

Q96P63	SPB12_HUMAN	Serpin B12	11604408	SERPINB12 is a novel member of the human ov-serpin family that is widely expressed and inhibits trypsin-like serine proteinases.

P45954	ACDSB_HUMAN	Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial	7698750	Isolation and expression of a cDNA encoding the precursor for a novel member (ACADSB) of the acyl-CoA dehydrogenase gene family.

P97481	EPAS1_MOUSE	Endothelial PAS domain-containing protein 1	9113979	A novel bHLH-PAS factor with close sequence similarity to hypoxia- inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development.

O94992	HEXI1_HUMAN	Protein HEXIM1	12581153	Suppression of NF-kappaB-dependent gene expression by a hexamethylene bisacetamide-inducible protein HEXIM1 in human vascular smooth muscle cells.

Q38806	HSP22_ARATH	22.0 kDa heat shock protein	7870826	An endomembrane-localized small heat-shock protein from Arabidopsis thaliana.

P60660	MYL6_HUMAN	Myosin light polypeptide 6	2304459	Characterization of human myosin light chains 1sa and 3nm: implications for isoform evolution and function.

Q9UKR8	TSN16_HUMAN	Tetraspanin-16	10500248	The molecular characterisation of a novel tetraspanin protein, TM4- B.

Q8LAZ7	CSN5B_ARATH	COP9 signalosome complex subunit 5b	12615944	Characterization of the last subunit of the Arabidopsis COP9 signalosome: implications for the overall structure and origin of the complex.

Q3MUY2	PIGY_HUMAN	Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y	16162815	The initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-Y, a seventh component.

Q9W1U5	GR59C_DROME	Putative gustatory receptor 59c	10710312	Candidate taste receptors in Drosophila.

Q08931	PRM3_YEAST	Pheromone-regulated membrane protein 3	12514182	Bipartite signals mediate subcellular targeting of tail-anchored membrane proteins in Saccharomyces cerevisiae.

P13656	CHIA_ECOLI	Probable bifunctional chitinase/lysozyme	10760150	The ChiA (YheB) protein of Escherichia coli K-12 is an endochitinase whose gene is negatively controlled by the nucleoid-structuring protein H-NS.

Q9URB4	ALF_CANAL	Fructose-bisphosphate aldolase	11681208	Analysis of the serologic response to systemic Candida albicans infection in a murine model.

P33947	ERD22_HUMAN	ER lumen protein retaining receptor 2	1316805	A brefeldin A-like phenotype is induced by the overexpression of a human ERD-2-like protein, ELP-1.

O08719	EVL_RAT	Ena/VASP-like protein	9268706	Differential display cloning of a novel rat cDNA (RNB6) that shows high expression in the neonatal brain revealed a member of Ena/VASP family.

P83295	GR64C_DROME	Putative gustatory receptor 64c	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

P23291	KC11_YEAST	Casein kinase I homolog 1	1627830	Two genes in Saccharomyces cerevisiae encode a membrane-bound form of casein kinase-1.

P92941	CLCA_ARATH	Chloride channel protein CLC-a	10758477	Disruption of putative anion channel gene AtCLC-a in Arabidopsis suggests a role in the regulation of nitrate content.

Q14011	CIRBP_HUMAN	Cold-inducible RNA-binding protein	11574538	The UV-inducible RNA-binding protein A18 (A18 hnRNP) plays a protective role in the genotoxic stress response.

O94316	SN114_SCHPO	114 kDa U5 small nuclear ribonucleoprotein component homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P43392	MT1A_ARATH	Metallothionein-like protein 1A	7612924	Transcripts of metallothionein genes in Arabidopsis thaliana.

Q9UHI5	LAT2_HUMAN	Large neutral amino acids transporter small subunit 2	10391915	Identification of a membrane protein, LAT-2, that co-expresses with 4F2 heavy chain, an L-type amino acid transport activity with broad specificity for small and large zwitterionic amino acids.

Q9M401	BCAT3_ARATH	Branched-chain-amino-acid aminotransferase 3, chloroplastic	12068099	The branched-chain amino acid transaminase gene family in Arabidopsis encodes plastid and mitochondrial proteins.

Q15760	GPR19_HUMAN	Probable G-protein coupled receptor 19	8830667	A novel gene codes for a putative G protein-coupled receptor with an abundant expression in brain.

Q9V464	ASF1_DROME	Histone chaperone asf1	10591219	The RCAF complex mediates chromatin assembly during DNA replication and repair.

Q9Y6K1	DNM3A_HUMAN	DNA (cytosine-5)-methyltransferase 3A	16682412	The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells.

P63345	ARC_MYCTU	Proteasome-associated ATPase	15659170	Characterization of a Mycobacterium tuberculosis proteasomal ATPase homologue.

Q9WVR3	SHIP2_RAT	Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2	17535963	An essential role for the SHIP2-dependent negative feedback loop in neuritogenesis of nerve growth factor-stimulated PC12 cells.

P40424	PBX1_HUMAN	Pre-B-cell leukemia transcription factor 1	10052460	Structure of a HoxB1-Pbx1 heterodimer bound to DNA: role of the hexapeptide and a fourth homeodomain helix in complex formation.

Q12802	AKP13_HUMAN	A-kinase anchor protein 13	1618839	Association of the type II cAMP-dependent protein kinase with a human thyroid RII-anchoring protein. Cloning and characterization of the RII-binding domain.

P31942	HNRH3_HUMAN	Heterogeneous nuclear ribonucleoprotein H3	10858537	The hnRNP 2H9 gene, which is involved in the splicing reaction, is a multiply spliced gene.

P38869	SVP26_YEAST	Protein SVP26	16107716	Immunoisolaton of the yeast Golgi subcompartments and characterization of a novel membrane protein, Svp26, discovered in the Sed5-containing compartments.

Q9LSE2	ICE1_ARATH	Transcription factor ICE1	17416732	SIZ1-mediated sumoylation of ICE1 controls CBF3/DREB1A expression and freezing tolerance in Arabidopsis.

P02489	CRYAA_HUMAN	Alpha-crystallin A chain	14512969	Cell death triggered by a novel mutation in the alphaA-crystallin gene underlies autosomal dominant cataract linked to chromosome 21q.

Q90655	AKR_CHICK	Homeobox protein AKR	7667102	Isolation and characterization of the chicken homeodomain protein AKR.

P40364	MPM1_YEAST	Mitochondrial peculiar membrane protein 1	11791739	A novel protein, Mpm1, of the mitochondria of the yeast Saccharomyces cerevisiae.

Q15185	TEBP_HUMAN	Prostaglandin E synthase 3	8114727	Characterization of a novel 23-kilodalton protein of unactive progesterone receptor complexes.

Q3ZU82	GOGA5_RAT	Golgin subfamily A member 5	12656988	Golgin-84 is a rab1 binding partner involved in Golgi structure.

O60683	PEX10_HUMAN	Peroxisome biogenesis factor 10	9683594	Identification of PEX10, the gene defective in complementation group 7 of the peroxisome-biogenesis disorders.

P50408	VATF_RAT	V-type proton ATPase subunit F	8621738	Identification of a 14-kDa subunit associated with the catalytic sector of clathrin-coated vesicle H+-ATPase.

O81445	CNBL1_ARATH	Calcineurin B-like protein 1	10590166	Novel protein kinases associated with calcineurin B-like calcium sensors in Arabidopsis.

P97678	KCMB1_RAT	Calcium-activated potassium channel subunit beta-1	9888999	Human and rodent MaxiK channel beta-subunit genes: cloning and characterization.

Q13616	CUL1_HUMAN	Cullin-1	18203720	Diversity in tissue expression, substrate binding, and SCF complex formation for a lectin family of ubiquitin ligases.

Q9VNS0	MAEL_DROME	Protein maelstrom	9409682	maelstrom is required for an early step in the establishment of Drosophila oocyte polarity: posterior localization of grk mRNA.

O43506	ADA20_HUMAN	Disintegrin and metalloproteinase domain-containing protein 20	9469942	ADAM 20 and 21; two novel human testis-specific membrane metalloproteases with similarity to fertilin-alpha.

P53759	DUS1_YEAST	tRNA-dihydrouridine synthase 1	12003496	A conserved family of Saccharomyces cerevisiae synthases effects dihydrouridine modification of tRNA.

P51142	DVL2_XENLA	Segment polarity protein dishevelled homolog DVL-2	15548584	Regional requirements for Dishevelled signaling during Xenopus gastrulation: separable effects on blastopore closure, mesendoderm internalization and archenteron formation.

Q9FI99	CNGT1_ARATH	Cytokinin-N-glucosyltransferase 1	15342621	N-glucosylation of cytokinins by glycosyltransferases of Arabidopsis thaliana.

Q6BER6	MED21_CAEEL	Mediator of RNA polymerase II transcription subunit 21	10611325	Caenorhabditis elegans mediator complexes are required for developmental-specific transcriptional activation.

P26151	FCGR1_MOUSE	High affinity immunoglobulin gamma Fc receptor I	11911824	FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection.

P46889	FTSK_ECOLI	DNA translocase ftsK	10922461	Membrane topology of the N-terminus of the Escherichia coli FtsK division protein.

P06367	RS14A_YEAST	40S ribosomal protein S14-A	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

P53157	FMP37_YEAST	UPF0041 protein FMP37	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P30083	VIPR1_RAT	Vasoactive intestinal polypeptide receptor 1	1314625	Functional expression and tissue distribution of a novel receptor for vasoactive intestinal polypeptide.

Q9CR42	ANKR1_MOUSE	Ankyrin repeat domain-containing protein 1	9043061	CARP, a cardiac ankyrin repeat protein, is downstream in the Nkx2-5 homeobox gene pathway.

P40008	FMP52_YEAST	Protein FMP52, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P38071	ETR1_YEAST	Enoyl-[acyl-carrier protein] reductase [NADPH, B-specific], mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q9M012	PR1B5_ARATH	PRA1 family protein B5	18583532	The PRA1 gene family in Arabidopsis.

Q14168	MPP2_HUMAN	MAGUK p55 subfamily member 2	7590743	A gene (DLG2) located at 17q12-q21 encodes a new homologue of the Drosophila tumor suppressor dlg-A.

P09093	CEL3A_HUMAN	Chymotrypsin-like elastase family member 3A	2826474	Identification of a novel class of elastase isozyme, human pancreatic elastase III, by cDNA and genomic gene cloning.

O14325	YB7A_SCHPO	Uncharacterized AAA domain-containing protein C16E9.10c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P04275	VWF_HUMAN	von Willebrand factor	10887119	A novel von Willebrand disease-causing mutation (Arg273Trp) in the von Willebrand factor propeptide that results in defective multimerization and secretion.

Q99470	SDF2_HUMAN	Stromal cell-derived factor 2	8918255	Isolation and characterization of a novel secretory protein, stromal cell-derived factor-2 (SDF-2) using the signal sequence trap method.

P08195	4F2_HUMAN	4F2 cell-surface antigen heavy chain	9878049	Amino acid transport of y+L-type by heterodimers of 4F2hc/CD98 and members of the glycoprotein-associated amino acid transporter family.

P63272	SPT4H_HUMAN	Transcription elongation factor SPT4	9450929	DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs.

Q04693	RSE1_YEAST	Pre-mRNA-splicing factor RSE1	15565172	Proteomic analysis identifies a new complex required for nuclear pre- mRNA retention and splicing.

Q7XKD0	TRXX_ORYSJ	Thioredoxin X, chloroplastic	16891402	Rice NTRC is a high-efficiency redox system for chloroplast protection against oxidative damage.

O95822	DCMC_HUMAN	Malonyl-CoA decarboxylase, mitochondrial	10417274	The molecular basis of malonyl-CoA decarboxylase deficiency.

Q9BWD1	THIC_HUMAN	Acetyl-CoA acetyltransferase, cytosolic	7911016	Molecular cloning and nucleotide sequence of complementary DNA for human hepatic cytosolic acetoacetyl-coenzyme A thiolase.

Q96DA6	TIM14_HUMAN	Mitochondrial import inner membrane translocase subunit TIM14	12592411	Characterization of the human heart mitochondrial proteome.

P08067	UCRI_YEAST	Cytochrome b-c1 complex subunit Rieske, mitochondrial	3036836	Isolation and characterization of the nuclear gene encoding the Rieske iron-sulfur protein (RIP1) from Saccharomyces cerevisiae.

Q96CS2	HAUS1_HUMAN	HAUS augmin-like complex subunit 1	19369198	The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells.

Q9Y697	NFS1_HUMAN	Cysteine desulfurase, mitochondrial	18650437	A novel role for human Nfs1 in the cytoplasm: Nfs1 acts as a sulfur donor for MOCS3, a protein involved in molybdenum cofactor biosynthesis.

P14091	CATE_HUMAN	Cathepsin E	2674141	Human gastric cathepsin E. Predicted sequence, localization to chromosome 1, and sequence homology with other aspartic proteinases.

C0LGT1	Y5129_ARATH	Probable LRR receptor-like serine/threonine-protein kinase At5g10290	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q9LRB5	LHT2_ARATH	Lysine histidine transporter 2	15361141	Selective expression of a novel high-affinity transport system for acidic and neutral amino acids in the tapetum cells of Arabidopsis flowers.

Q9Y7U6	RGF1_SCHPO	Rho1 guanine nucleotide exchange factor 1	16291723	Cell wall remodeling at the fission yeast cell division site requires the Rho-GEF Rgf3p.

Q91550	ILF3A_XENLA	Interleukin enhancer-binding factor 3-A	9710639	The maternal CCAAT box transcription factor which controls GATA-2 expression is novel and developmentally regulated and contains a double-stranded-RNA-binding subunit.

P26358	DNMT1_HUMAN	DNA (cytosine-5)-methyltransferase 1	16357870	The Polycomb group protein EZH2 directly controls DNA methylation.

O94324	PPK31_SCHPO	Serine/threonine-protein kinase ppk31	15821139	Systematic deletion analysis of fission yeast protein kinases.

Q9JIH7	WNK1_RAT	Serine/threonine-protein kinase WNK1	10828064	WNK1, a novel mammalian serine/threonine protein kinase lacking the catalytic lysine in subdomain II.

Q965H3	SOP2_CAEEL	Polycomb protein sop-2	12791274	Global regulation of Hox gene expression in C. elegans by a SAM domain protein.

P11309	PIM1_HUMAN	Proto-oncogene serine/threonine-protein kinase pim-1	16186805	The 44 kDa Pim-1 kinase directly interacts with tyrosine kinase Etk/BMX and protects human prostate cancer cells from apoptosis induced by chemotherapeutic drugs.

P48607	SPZ_DROME	Protein spaetzle	8124709	The spatzle gene encodes a component of the extracellular signaling pathway establishing the dorsal-ventral pattern of the Drosophila embryo.

Q39253	CAX1_ARATH	Vacuolar cation/proton exchanger 1	15862304	Evidence of differential pH regulation of the Arabidopsis vacuolar Ca2+/H+ antiporters CAX1 and CAX2.

Q76NV5	HPPD_DICDI	4-hydroxyphenylpyruvate dioxygenase	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P50112	KNH1_YEAST	Cell wall synthesis protein KNH1	8810042	The KNH1 gene of Saccharomyces cerevisiae is a functional homolog of KRE9.

Q06504	NAT3_YEAST	N-terminal acetyltransferase B complex catalytic subunit NAT3	10545125	Identification and specificities of N-terminal acetyltransferases from Saccharomyces cerevisiae.

Q4LCS9	TXA22_ANDAU	Beta-toxin KAaH2	15656785	A new type of scorpion Na+-channel-toxin-like polypeptide active on K+ channels.

P40462	TM108_YEAST	Protein TMA108	14562095	Global analysis of protein localization in budding yeast.

Q9VJS7	PBURS_DROME	Partner of bursicon	15703293	Bursicon, the insect cuticle-hardening hormone, is a heterodimeric cystine knot protein that activates G protein-coupled receptor LGR2.

Q6S7F2	E2F7_MOUSE	Transcription factor E2F7	12893818	Identification and characterization of E2F7, a novel mammalian E2F family member capable of blocking cellular proliferation.

Q13946	PDE7A_HUMAN	High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	8389765	Isolation and characterization of a previously undetected human cAMP phosphodiesterase by complementation of cAMP phosphodiesterase- deficient Saccharomyces cerevisiae.

Q9H074	PAIP1_HUMAN	Polyadenylate-binding protein-interacting protein 1	10970864	Multiple portions of poly(A)-binding protein stimulate translation in vivo.

Q07825	XPP_YEAST	Putative Xaa-Pro aminopeptidase	14562095	Global analysis of protein localization in budding yeast.

Q15796	SMAD2_HUMAN	Mothers against decapentaplegic homolog 2	16200078	Cloning and functional characterization of a new Ski homolog, Fussel- 18, specifically expressed in neuronal tissues.

P36096	TUL1_YEAST	Transmembrane E3 ubiquitin-protein ligase 1	11788821	A transmembrane ubiquitin ligase required to sort membrane proteins into multivesicular bodies.

O35430	APBA1_RAT	Amyloid beta A4 precursor protein-binding family A member 1	9395480	Mints, Munc18-interacting proteins in synaptic vesicle exocytosis.

P32501	EI2BE_YEAST	Translation initiation factor eIF-2B subunit epsilon	8506384	A protein complex of translational regulators of GCN4 mRNA is the guanine nucleotide-exchange factor for translation initiation factor 2 in yeast.

Q9R1K9	CETN2_MOUSE	Centrin-2	11250075	Characterization of the X-linked murine centrin Cetn2 gene.

Q9Z2Y1	TIM_RAT	Protein timeless homolog	11112428	Molecular characterization and nuclear localization of rat timeless- like gene product.

Q39163	TGA5_ARATH	Transcription factor TGA5	10659709	NPR1 differentially interacts with members of the TGA/OBF family of transcription factors that bind an element of the PR-1 gene required for induction by salicylic acid.

Q9P7K5	GIT1_SCHPO	Adenylate cyclase activation protein git1	16489217	Schizosaccharomyces pombe Git1 is a C2-domain protein required for glucose activation of adenylate cyclase.

Q9R1R0	LHX6_MOUSE	LIM/homeobox protein Lhx6	10393337	A brain region-specific gene product Lhx6.1 interacts with Ldb1 through tandem LIM-domains.

P54071	IDHP_MOUSE	Isocitrate dehydrogenase [NADP], mitochondrial	8867815	Molecular cloning of the cDNA of mouse mitochondrial NADP-dependent isocitrate dehydrogenase and the expression of the gene during lymphocyte activation.

P63101	1433Z_MOUSE	14-3-3 protein zeta/delta	12176995	MADM, a novel adaptor protein that mediates phosphorylation of the 14-3-3 binding site of myeloid leukemia factor 1.

Q91V27	MELPH_MOUSE	Melanophilin	11504925	Mutations in Mlph, encoding a member of the Rab effector family, cause the melanosome transport defects observed in leaden mice.

P48559	YPT11_YEAST	GTP-binding protein YPT11	16980630	Bioinformatic and comparative localization of Rab proteins reveals functional insights into the uncharacterized GTPases Ypt10p and Ypt11p.

Q9JHJ8	ICOSL_MOUSE	ICOS ligand	10657606	Identification of GL50, a novel B7-like protein that functionally binds to ICOS receptor.

Q940X7	RBX1A_ARATH	RING-box protein 1a	16844902	Arabidopsis CULLIN4 forms an E3 ubiquitin ligase with RBX1 and the CDD complex in mediating light control of development.

P49025	CTRO_MOUSE	Citron Rho-interacting kinase	9792683	Citron Rho-interacting kinase, a novel tissue-specific Ser/Thr kinase encompassing the Rho-Rac-binding protein Citron.

P85411	KTDAP_RAT	Keratinocyte differentiation-associated protein	11054531	Kdap, a novel gene associated with the stratification of the epithelium.

P25534	UBIH_ECOLI	2-octaprenyl-6-methoxyphenol hydroxylase	1339425	Isolation and characterization of a light-sensitive mutant of Escherichia coli K-12 with a mutation in a gene that is required for the biosynthesis of ubiquinone.

O60260	PRKN2_HUMAN	E3 ubiquitin-protein ligase parkin	16332688	Parkin ubiquitinates and promotes the degradation of RanBP2.

Q38857	XTH22_ARATH	Xyloglucan endotransglucosylase/hydrolase protein 22	10406121	In vitro activities of four xyloglucan endotransglycosylases from Arabidopsis.

Q63447	NPY4R_RAT	Neuropeptide Y receptor type 4	8643536	The cloned rat pancreatic polypeptide receptor exhibits profound differences to the orthologous receptor.

P62260	1433E_RAT	14-3-3 protein epsilon	8694795	Association of a 14-3-3 protein with CMP-NeuAc:GM1 alpha 2,3- sialyltransferase.

P46416	GSHB_ARATH	Glutathione synthetase, chloroplastic	8914526	Cloning of the cDNA and genomic clones for glutathione synthetase from Arabidopsis thaliana and complementation of a gsh2 mutant in fission yeast.

P83443	MDO1_PSEMR	Macrodontain-1	10686143	Purification and characterization of macrodontain I, a cysteine peptidase from unripe fruits of Pseudananas macrodontes (Morr.) Harms (Bromeliaceae).

Q9Y230	RUVB2_HUMAN	RuvB-like 2	14966270	Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans.

Q9Z2K1	K1C16_MOUSE	Keratin, type I cytoskeletal 16	16702408	Keratin 17 modulates hair follicle cycling in a TNFalpha-dependent fashion.

P30508	1C12_HUMAN	HLA class I histocompatibility antigen, Cw-12 alpha chain	2843461	Cloning and analysis of HLA class I cDNA encoding a new HLA-C specificity Cx52.

O60907	TBL1X_HUMAN	F-box-like/WD repeat-containing protein TBL1X	10330347	X-linked late-onset sensorineural deafness caused by a deletion involving OA1 and a novel gene containing WD-40 repeats.

P38844	DSE2_YEAST	Protein DSE2	11747810	Yeast Cbk1 and Mob2 activate daughter-specific genetic programs to induce asymmetric cell fates.

Q8NHV9	RHXF1_HUMAN	Rhox homeobox family member 1	11980563	OTEX, an androgen-regulated human member of the paired-like class of homeobox genes.

P08970	SUHW_DROME	Protein suppressor of hairy wing	15574329	The centrosomal protein CP190 is a component of the gypsy chromatin insulator.

Q9UHI5	LAT2_HUMAN	Large neutral amino acids transporter small subunit 2	15918515	Reabsorption of neutral amino acids mediated by amino acid transporter LAT2 and TAT1 in the basolateral membrane of proximal tubule.

Q02647	DYL1_YEAST	Dynein light chain 1, cytoplasmic	8628245	Molecular and genetic characterization of SLC1, a putative Saccharomyces cerevisiae homolog of the metazoan cytoplasmic dynein light chain 1.

Q12772	SRBP2_HUMAN	Sterol regulatory element-binding protein 2	7903453	SREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element.

O94292	RM38_SCHPO	54S ribosomal protein L38, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P23443	KS6B1_HUMAN	Ribosomal protein S6 kinase beta-1	19085255	Regulation and localization of ribosomal protein S6 kinase 1 isoforms.

P0AC44	DHSD_ECOLI	Succinate dehydrogenase hydrophobic membrane anchor subunit	9521736	Localization of histidine residues responsible for heme axial ligation in cytochrome b556 of complex II (succinate:ubiquinone oxidoreductase) in Escherichia coli.

P51906	EAA3_MOUSE	Excitatory amino acid transporter 3	12119102	Molecular cloning, gene structure, expression profile and functional characterization of the mouse glutamate transporter (EAAT3) interacting protein GTRAP3-18.

Q84XU2	PPP5_ARATH	Serine/threonine-protein phosphatase 5	15707897	Phytochrome-specific type 5 phosphatase controls light signal flux by enhancing phytochrome stability and affinity for a signal transducer.

O74759	YBE4_SCHPO	PHD finger protein C17D11.04c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P59054	CSRN1_MOUSE	Cysteine/serine-rich nuclear protein 1	17726538	Characterization of a family of novel cysteine- serine-rich nuclear proteins (CSRNP).

Q8LGG0	FKB12_ARATH	Peptidyl-prolyl isomerase FKBP12	9807817	An Arabidopsis immunophilin, AtFKBP12, binds to AtFIP37 (FKBP interacting protein) in an interaction that is disrupted by FK506.

Q9FNL7	PTR3_ARATH	Peptide transporter PTR3-A	17143616	AtPTR3, a wound-induced peptide transporter needed for defence against virulent bacterial pathogens in Arabidopsis.

Q05707	COEA1_HUMAN	Collagen alpha-1(XIV) chain	9427527	Complete primary structure of human collagen type XIV (undulin).

P13693	TCTP_HUMAN	Translationally-controlled tumor protein	7542803	Molecular identification of an IgE-dependent histamine-releasing factor.

P61202	CSN2_MOUSE	COP9 signalosome complex subunit 2	9707402	The COP9 complex is conserved between plants and mammals and is related to the 26S proteasome regulatory complex.

P22570	ADRO_HUMAN	NADPH:adrenodoxin oxidoreductase, mitochondrial	2845396	Human adrenodoxin reductase: two mRNAs encoded by a single gene on chromosome 17cen-->q25 are expressed in steroidogenic tissues.

Q9T053	PLDG1_ARATH	Phospholipase D gamma 1	9353280	Molecular heterogeneity of phospholipase D (PLD). Cloning of PLDgamma and regulation of plant PLDgamma, -beta, and -alpha by polyphosphoinositides and calcium.

P53941	IMP4_YEAST	U3 small nucleolar ribonucleoprotein protein IMP4	15489263	Imp3p and Imp4p mediate formation of essential U3-precursor rRNA (pre-rRNA) duplexes, possibly to recruit the small subunit processome to the pre-rRNA.

A2AWL7	MGAP_MOUSE	MAX gene-associated protein	10601024	Mga, a dual-specificity transcription factor that interacts with Max and contains a T-domain DNA-binding motif.

O94438	RS3A2_SCHPO	40S ribosomal protein S1-B	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P27692	SPT5_YEAST	Transcription elongation factor SPT5	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q924Z9	NET1_RAT	Netrin-1	11356879	Widespread expression of netrin-1 by neurons and oligodendrocytes in the adult mammalian spinal cord.

P48167	GLRB_HUMAN	Glycine receptor subunit beta	11929858	Hyperekplexia associated with compound heterozygote mutations in the beta-subunit of the human inhibitory glycine receptor (GLRB).

P26374	RAE2_HUMAN	Rab proteins geranylgeranyltransferase component A 2	1301160	An autosomal homologue of the choroideremia gene colocalizes with the Usher syndrome type II locus on the distal part of chromosome 1q.

Q9I9R3	S40A1_DANRE	Solute carrier family 40 member 1	10693807	Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter.

Q9ESJ1	CABL1_MOUSE	CDK5 and ABL1 enzyme substrate 1	10896159	Cables links Cdk5 and c-Abl and facilitates Cdk5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth.

Q96305	GRXC7_ARATH	Glutaredoxin-C7	15728668	ROXY1, a member of the plant glutaredoxin family, is required for petal development in Arabidopsis thaliana.

Q9WVR3	SHIP2_RAT	Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2	10381377	Molecular cloning of rat SH2-containing inositol phosphatase 2 (SHIP2) and its role in the regulation of insulin signaling.

P36888	FLT3_HUMAN	FL cytokine receptor	7507245	STK-1, the human homolog of Flk-2/Flt-3, is selectively expressed in CD34+ human bone marrow cells and is involved in the proliferation of early progenitor/stem cells.

P37202	DIS3_SCHPO	Exosome complex exonuclease dis3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NPC6	MYOZ2_HUMAN	Myozenin-2	11114196	Calsarcins, a novel family of sarcomeric calcineurin-binding proteins.

O08537	ESR2_MOUSE	Estrogen receptor beta	9058381	Cloning, chromosomal localization, and functional analysis of the murine estrogen receptor beta.

P20815	CP3A5_HUMAN	Cytochrome P450 3A5	2732228	Cytochrome P-450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver. cDNA and deduced amino acid sequence and distinct specificities of cDNA- expressed hPCN1 and hPCN3 for the metabolism of steroid hormones and cyclosporine.

O43184	ADA12_HUMAN	Disintegrin and metalloproteinase domain-containing protein 12	15574124	FLRG, a new ADAM12-associated protein, modulates osteoclast differentiation.

Q99445	GML_HUMAN	Glycosyl-phosphatidylinositol-anchored molecule-like protein	8934543	Isolation of a novel GPI-anchored gene specifically regulated by p53; correlation between its expression and anti-cancer drug sensitivity.

P41732	TSN7_HUMAN	Tetraspanin-7	8420826	Isolation of a novel cDNA clone showing marked similarity to ME491/CD63 superfamily.

P0AFZ5	SULA_ECOLI	Cell division inhibitor sulA	6087326	Cell-division control in Escherichia coli: specific induction of the SOS function SfiA protein is sufficient to block septation.

Q9Y5Y5	PEX16_HUMAN	Peroxisomal membrane protein PEX16	16717127	The origin and maintenance of mammalian peroxisomes involves a de novo PEX16-dependent pathway from the ER.

Q8BGW0	THMS1_MOUSE	Protein THEMIS	19597497	Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection.

Q27489	H33L3_CAEEL	Putative histone H3.3-like type 3	14551910	Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions.

P84273	DAH11_LITDA	Dahlein-1.1	11555873	Bioactive dahlein peptides from the skin secretions of the Australian aquatic frog Litoria dahlii: sequence determination by electrospray mass spectrometry.

P38631	FKS1_YEAST	1,3-beta-glucan synthase component FKS1	7528927	The Saccharomyces cerevisiae FKS1 (ETG1) gene encodes an integral membrane protein which is a subunit of 1,3-beta-D-glucan synthase.

Q9VYS4	GLD2B_DROME	Poly(A) RNA polymerase gld-2 homolog B	12871909	Regulation of maternal transcript destabilization during egg activation in Drosophila.

P25859	CKB11_ARATH	Cyclin-dependent kinase B1-1	9276444	The Arabidopsis Cks1At protein binds the cyclin-dependent kinases Cdc2aAt and Cdc2bAt.

P18334	CSK2A_CAEEL	Casein kinase II subunit alpha	16481400	Casein kinase II and calcineurin modulate TRPP function and ciliary localization.

Q5SSZ5	TENS3_MOUSE	Tensin-3	15733665	Inactivation of tensin3 in mice results in growth retardation and postnatal lethality.

Q9HGM3	RCA1_SCHPO	Mitochondrial respiratory chain complexes assembly protein rca1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P21461	SINA_DROME	E3 ubiquitin-protein ligase sina	9267026	PHYL acts to down-regulate TTK88, a transcriptional repressor of neuronal cell fates, by a SINA-dependent mechanism.

Q91WU6	ZDHC7_MOUSE	Palmitoyltransferase ZDHHC7	15603741	Identification of PSD-95 palmitoylating enzymes.

O75364	PITX3_HUMAN	Pituitary homeobox 3	9620774	A novel homeobox gene PITX3 is mutated in families with autosomal- dominant cataracts and ASMD.

Q02889	MGR2_YEAST	Protein MGR2	16267274	A genomewide screen for petite-negative yeast strains yields a new subunit of the i-AAA protease complex.

Q5SW96	ARH_HUMAN	Low density lipoprotein receptor adapter protein 1	12451172	The autosomal recessive hypercholesterolemia (ARH) protein interfaces directly with the clathrin-coat machinery.

O14503	BHE40_HUMAN	Class E basic helix-loop-helix protein 40	9240428	Molecular characterization of the novel basic helix-loop-helix protein DEC1 expressed in differentiated human embryo chondrocytes.

P97443	SMYD1_MOUSE	SET and MYND domain-containing protein 1	11923873	Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis.

Q9D5S1	TX19B_MOUSE	Testis-expressed protein 19.2	18096721	Tex19, a mammalian-specific protein with a restricted expression in pluripotent stem cells and germ line.

Q9FLP0	MA651_ARATH	65-kDa microtubule-associated protein 1	11701884	Role of SH3 domain-containing proteins in clathrin-mediated vesicle trafficking in Arabidopsis.

Q05062	CDC42_CAEEL	Cell division control protein 42 homolog	11412996	CDC-42 regulates PAR protein localization and function to control cellular and embryonic polarity in C. elegans.

Q9NAN2	PAR6_CAEEL	Partitioning defective protein 6	13129846	C. elegans PAR-3 and PAR-6 are required for apicobasal asymmetries associated with cell adhesion and gastrulation.

Q9USR5	THOC5_SCHPO	Uncharacterized THOC5 family protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P83748	PRS30_RAT	Serine protease 30	14669991	Cloning and characterization of a transmembrane-type serine protease from rat kidney, a new sodium channel activator.

P47017	LSM1_YEAST	Sm-like protein LSm1	10747033	A Sm-like protein complex that participates in mRNA degradation.

P83145	UK114_CHICK	Ribonuclease UK114	11163312	Purification, characterization and developmental expression of chick (Gallus domesticus) liver PSP protein.

Q9SIS3	MA656_ARATH	65-kDa microtubule-associated protein 6	15469496	Molecular dissection of plant cytokinesis and phragmoplast structure: a survey of GFP-tagged proteins.

Q99456	K1C12_HUMAN	Keratin, type I cytoskeletal 12	9171831	Mutations in cornea-specific keratin K3 or K12 genes cause Meesmann's corneal dystrophy.

O64629	AUR3_ARATH	Serine/threonine-protein kinase Aurora-3	15469496	Molecular dissection of plant cytokinesis and phragmoplast structure: a survey of GFP-tagged proteins.

P34219	TOD6_YEAST	Transcriptional regulatory protein TOD6	19040720	Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment.

P30793	GCH1_HUMAN	GTP cyclohydrolase 1	11284739	GTP cyclohydrolase I mRNA: novel splice variants in the slime mould Physarum polycephalum and in human monocytes (THP-1) indicate conservation of mRNA processing.

P46414	CDN1B_MOUSE	Cyclin-dependent kinase inhibitor 1B	8033213	p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21.

Q9GK76	PTAFR_CAPHI	Platelet-activating factor receptor	11916258	Comparison of the coding sequence of the platelet-activating factor receptor gene in three species.

Q96JF0	SIAT2_HUMAN	Beta-galactoside alpha-2,6-sialyltransferase 2	12235148	Characterization of the second type of human beta-galactoside alpha2,6-sialyltransferase (ST6Gal II) that sialylates Galbeta1,4GlcNAc structures on oligosaccharides preferentially.

Q8VXV7	LDL1_ARATH	Lysine-specific histone demethylase 1 homolog 1	17921315	Arabidopsis relatives of the human lysine-specific demethylase1 repress the expression of FWA and FLOWERING LOCUS C and thus promote the floral transition.

O09014	S15A4_RAT	Solute carrier family 15 member 4	9092568	Cloning and functional expression of a brain peptide/histidine transporter.

P50591	TNF10_HUMAN	Tumor necrosis factor ligand superfamily member 10	8777713	Identification and characterization of a new member of the TNF family that induces apoptosis.

Q96FV9	THOC1_HUMAN	THO complex subunit 1	7525595	The amino-terminal region of the retinoblastoma gene product binds a novel nuclear matrix protein that co-localizes to centers for RNA processing.

P32490	MKK1_YEAST	MAP kinase kinase MKK1/SSP32	8386320	MKK1 and MKK2, which encode Saccharomyces cerevisiae mitogen- activated protein kinase-kinase homologs, function in the pathway mediated by protein kinase C.

P04406	G3P_HUMAN	Glyceraldehyde-3-phosphate dehydrogenase	7030790	The complete amino acid sequence of human muscle glyceraldehyde 3- phosphate dehydrogenase.

Q8NK92	AORSN_ASPOR	Aorsin	12519073	Aorsin, a novel serine proteinase with trypsin-like specificity at acidic pH.

O94668	NSE5_SCHPO	Non-structural maintenance of chromosome element 5	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O74469	YQC7_SCHPO	Exosome complex protein C1739.07	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O95352	ATG7_HUMAN	Ubiquitin-like modifier-activating enzyme ATG7	10233149	Glucose-induced autophagy of peroxisomes in Pichia pastoris requires a unique E1-like protein.

O59703	GGPPS_SCHPO	Geranylgeranyl pyrophosphate synthase	17596513	Geranylgeranyl diphosphate synthase in fission yeast is a heteromer of farnesyl diphosphate synthase (FPS), Fps1, and an FPS-like protein, Spo9, essential for sporulation.

O49397	ARR10_ARATH	Two-component response regulator ARR10	15173562	Type-B response regulators display overlapping expression patterns in Arabidopsis.

P41821	MID1_YEAST	Stretch-activated cation channel MID1	14729456	Subcellular localization and oligomeric structure of the yeast putative stretch-activated Ca2+ channel component Mid1.

P27515	URK1_YEAST	Uridine kinase	10501935	New insights into the pyrimidine salvage pathway of Saccharomyces cerevisiae: requirement of six genes for cytidine metabolism.

Q91WG4	ELP2_MOUSE	Elongator complex protein 2	10954736	A Stat3-interacting protein (StIP1) regulates cytokine signal transduction.

Q14849	STAR3_HUMAN	StAR-related lipid transfer protein 3	9270027	Isolation of a candidate gene, CAB1, for cholesterol transport to mitochondria from the c-ERBB-2 amplicon by a modified cDNA selection method.

O13329	FOB1_YEAST	DNA replication fork-blocking protein FOB1	9078378	A yeast gene product, Fob1 protein, required for both replication fork blocking and recombinational hotspot activities.

P80318	TCPG_MOUSE	T-complex protein 1 subunit gamma	7953530	Identification of six Tcp-1-related genes encoding divergent subunits of the TCP-1-containing chaperonin.

Q9P2Y5	UVRAG_HUMAN	UV radiation resistance-associated gene protein	19270696	Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages.

Q9JLB2	MPP5_MOUSE	MAGUK p55 subfamily member 5	10753959	Molecular cloning and characterization of Pals, proteins associated with mLin-7.

P51123	TAF1_DROME	Transcription initiation factor TFIID subunit 1	15143281	TAF1 activates transcription by phosphorylation of serine 33 in histone H2B.

Q9FHW7	SKP1B_ARATH	SKP1-like protein 1B	14688296	The ASK1 and ASK2 genes are essential for Arabidopsis early development.

Q99612	KLF6_HUMAN	Krueppel-like factor 6	9689109	Zf9, a Kruppel-like transcription factor up-regulated in vivo during early hepatic fibrosis.

P48730	KC1D_HUMAN	Casein kinase I isoform delta	8786104	Sequence analysis of the cDNA for the human casein kinase I delta (CSNK1D) gene and its chromosomal localization.

Q43125	CRY1_ARATH	Cryptochrome-1	12846824	Novel ATP-binding and autophosphorylation activity associated with Arabidopsis and human cryptochrome-1.

Q02780	NFIA_MOUSE	Nuclear factor 1 A-type	9056636	Expression patterns of the four nuclear factor I genes during mouse embryogenesis indicate a potential role in development.

Q9JLZ3	AUHM_MOUSE	Methylglutaconyl-CoA hydratase, mitochondrial	10072761	Characterisation and mitochondrial localisation of AUH, an AU- specific RNA-binding enoyl-CoA hydratase.

P33893	GATB_YEAST	Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial	19417106	Yeast mitochondrial Gln-tRNA(Gln) is generated by a GatFAB-mediated transamidation pathway involving Arc1p-controlled subcellular sorting of cytosolic GluRS.

P70245	EBP_MOUSE	3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	10391218	Mutations in a delta(8)-delta(7) sterol isomerase in the tattered mouse and X-linked dominant chondrodysplasia punctata.

Q12306	SMT3_YEAST	Ubiquitin-like protein SMT3	10882122	Ulp1-SUMO crystal structure and genetic analysis reveal conserved interactions and a regulatory element essential for cell growth in yeast.

P23678	UN104_CAEEL	Kinesin-like protein unc-104	1846075	The C. elegans unc-104 gene encodes a putative kinesin heavy chain- like protein.

P33206	FXA4B_XENLA	Forkhead box protein A4-B	15656969	Of fox and frogs: fox (fork head/winged helix) transcription factors in Xenopus development.

Q810B3	BSH_MOUSE	Brain-specific homeobox protein homolog	17550780	A role for brain-specific homeobox factor bsx in the control of hyperphagia and locomotory behavior.

P25587	LDB16_YEAST	Protein LDB16	14562095	Global analysis of protein localization in budding yeast.

Q9PUN1	OCLN_XENLA	Occludin	10491082	Xenopus laevis occludin. Identification of in vitro phosphorylation sites by protein kinase CK2 and association with cingulin.

P10908	UGPQ_ECOLI	Glycerophosphoryl diester phosphodiesterase	18083802	Escherichia coli cytosolic glycerophosphodiester phosphodiesterase (UgpQ) requires Mg2+, Co2+, or Mn2+ for its enzyme activity.

Q9FQ08	KU70_ARATH	ATP-dependent DNA helicase 2 subunit KU70	16396834	A conserved and species-specific functional interaction between the Werner syndrome-like exonuclease atWEX and the Ku heterodimer in Arabidopsis.

P33890	TIR2_YEAST	Cold shock-induced protein TIR2	7746155	Cold-shock induction of a family of TIP1-related proteins associated with the membrane in Saccharomyces cerevisiae.

P14693	SAM35_YEAST	Sorting assembly machinery 35 kDa subunit	15205677	Tob38, a novel essential component in the biogenesis of beta-barrel proteins of mitochondria.

Q9W5E1	RBX1A_DROME	RING-box protein 1A	12062088	Drosophila Roc1a encodes a RING-H2 protein with a unique function in processing the Hh signal transducer Ci by the SCF E3 ubiquitin ligase.

P40074	AVT6_YEAST	Vacuolar amino acid transporter 6	11274162	A family of yeast proteins mediating bidirectional vacuolar amino acid transport.

Q9HE16	YI35_SCHPO	Uncharacterized transcriptional regulatory protein C1399.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9W2B2	GR48C_DROME	Putative gustatory receptor 58c	10710312	Candidate taste receptors in Drosophila.

O59767	MAD3_SCHPO	Mitotic spindle checkpoint component mad3	11909965	Fission yeast Mad3p is required for Mad2p to inhibit the anaphase- promoting complex and localizes to kinetochores in a Bub1p-, Bub3p-, and Mph1p-dependent manner.

Q8RXG3	M2K5_ARATH	Mitogen-activated protein kinase kinase 5	11875555	MAP kinase signalling cascade in Arabidopsis innate immunity.

Q9JJ22	ERAP1_RAT	Endoplasmic reticulum aminopeptidase 1	10824104	Molecular characterization of a puromycin-insensitive leucyl-specific aminopeptidase, PILS-AP.

P27139	CAH2_RAT	Carbonic anhydrase 2	9665810	Carbonic anhydrase II plays a major role in osteoclast differentiation and bone resorption by effecting the steady state intracellular pH and Ca2+.

P49189	AL9A1_HUMAN	4-trimethylaminobutyraldehyde dehydrogenase	8645224	Aldehyde dehydrogenase from adult human brain that dehydrogenates gamma-aminobutyraldehyde: purification, characterization, cloning and distribution.

Q12520	HUT1_YEAST	UDP-galactose transporter homolog 1	11284009	Overexpression of HUT1 gene stimulates in vivo galactosylation by enhancing UDP-galactose transport activity in Saccharomyces cerevisiae.

Q86WA9	S2611_HUMAN	Sodium-independent sulfate anion transporter	12626430	Molecular and functional characterization of SLC26A11, a sodium- independent sulfate transporter from high endothelial venules.

Q8C5D8	PIAS2_MOUSE	E3 SUMO-protein ligase PIAS2	11104669	p67 isoform of mouse disabled 2 protein acts as a transcriptional activator during the differentiation of F9 cells.

Q13393	PLD1_HUMAN	Phospholipase D1	8530346	Human ADP-ribosylation factor-activated phosphatidylcholine-specific phospholipase D defines a new and highly conserved gene family.

P25932	ESCA_DROME	Protein escargot	10562554	The mesoderm determinant snail collaborates with related zinc-finger proteins to control Drosophila neurogenesis.

P36408	GBB_DICDI	Guanine nucleotide-binding protein subunit beta	16135826	The phosducin-like protein PhLP1 is essential for Gbetagamma dimer formation in Dictyostelium discoideum.

P40438	VTH1_YEAST	Protein VTH1	8662642	Multiple pathways for vacuolar sorting of yeast proteinase A.

Q8DK70	ISPG_THEEB	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase	15792953	Cyanobacterial non-mevalonate pathway: (E)-4-hydroxy-3-methylbut-2- enyl diphosphate synthase interacts with ferredoxin in Thermosynechococcus elongatus BP-1.

Q8IWA5	CTL2_HUMAN	Choline transporter-like protein 2	10677542	An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteins.

P22108	APA2_YEAST	5',5'''-P-1,P-4-tetraphosphate phosphorylase 2	2174863	Catabolism of bis(5'-nucleosidyl) tetraphosphates in Saccharomyces cerevisiae.

P21461	SINA_DROME	E3 ubiquitin-protein ligase sina	11526076	A dual function of phyllopod in Drosophila external sensory organ development: cell fate specification of sensory organ precursor and its progeny.

P36542	ATPG_HUMAN	ATP synthase subunit gamma, mitochondrial	8227057	Gene structure of human mitochondrial ATP synthase gamma-subunit. Tissue specificity produced by alternative RNA splicing.

Q9NR56	MBNL1_HUMAN	Muscleblind-like protein 1	10970838	Recruitment of human muscleblind proteins to (CUG)(n) expansions associated with myotonic dystrophy.

Q06139	YL346_YEAST	Uncharacterized protein YLR346C, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

P05759	RS27A_YEAST	Ubiquitin-40S ribosomal protein S31	2538753	The tails of ubiquitin precursors are ribosomal proteins whose fusion to ubiquitin facilitates ribosome biogenesis.

Q9Y337	KLK5_HUMAN	Kallikrein-5	10514489	Purification, molecular cloning, and expression of a human stratum corneum trypsin-like serine protease with possible function in desquamation.

Q10264	PSO2_SCHPO	DNA cross-link repair protein pso2/snm1	12808110	Schizosaccharomyces pombe checkpoint response to DNA interstrand cross-links.

Q94129	WRT4_CAEEL	Warthog protein 4	8689684	Hedgehog patterning activity: role of a lipophilic modification mediated by the carboxy-terminal autoprocessing domain.

Q10290	MAL2_SCHPO	Chromosome segregation protein mal2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P63146	UBE2B_HUMAN	Ubiquitin-conjugating enzyme E2 B	20061386	The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.

Q9QZU4	HRSL1_MOUSE	HRAS-like suppressor	10542256	Molecular cloning and biological activity of a novel Ha-Ras suppressor gene predominantly expressed in skeletal muscle, heart, brain, and bone marrow by differential display using clonal mouse EC cells, ATDC5.

P48552	NRIP1_HUMAN	Nuclear receptor-interacting protein 1	11518808	A new human MR splice variant is a ligand-independent transactivator modulating corticosteroid action.

Q60177	PSA_METJA	Proteasome subunit alpha	10692374	Biochemical and physical properties of the Methanococcus jannaschii 20S proteasome and PAN, a homolog of the ATPase (Rpt) subunits of the eucaryal 26S proteasome.

Q16637	SMN_HUMAN	Survival motor neuron protein	16087681	Toward an assembly line for U7 snRNPs: interactions of U7-specific Lsm proteins with PRMT5 and SMN complexes.

O04983	ACCC_ARATH	Biotin carboxylase, chloroplastic	9414551	Biochemical and molecular biological characterization of CAC2, the Arabidopsis thaliana gene coding for the biotin carboxylase subunit of the plastidic acetyl-coenzyme A carboxylase.

P00748	FA12_HUMAN	Coagulation factor XII	2510163	Coagulation factor XII (Hageman factor) Washington D.C.: inactive factor XIIa results from Cys-571-->Ser substitution.

P38169	KMO_YEAST	Kynurenine 3-monooxygenase	14562095	Global analysis of protein localization in budding yeast.

P33300	SUR1_YEAST	Mannosyl phosphorylinositol ceramide synthase SUR1	12954640	Csg1p and newly identified Csh1p function in mannosylinositol phosphorylceramide synthesis by interacting with Csg2p.

O88543	CSN3_MOUSE	COP9 signalosome complex subunit 3	12972600	COP9 signalosome subunit 3 is essential for maintenance of cell proliferation in the mouse embryonic epiblast.

P36582	PCK1_SCHPO	Protein kinase C-like 1	8491190	Two novel protein kinase C-related genes of fission yeast are essential for cell viability and implicated in cell shape control.

Q9SYM4	TPS1_ARATH	Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 1	16553896	Delayed embryo development in the ARABIDOPSIS TREHALOSE-6-PHOSPHATE SYNTHASE 1 mutant is associated with altered cell wall structure, decreased cell division and starch accumulation.

P78854	PLB1_SCHPO	Lysophospholipase 1	12715160	The phospholipase B homolog Plb1 is a mediator of osmotic stress response and of nutrient-dependent repression of sexual differentiation in the fission yeast Schizosaccharomyces pombe.

Q9UGJ1	GCP4_HUMAN	Gamma-tubulin complex component 4	10562286	Human 76p: a new protein member of the gamma-tubulin associated protein family.

Q9SUM5	Y4318_ARATH	Uncharacterized protein At4g30180	12897250	The Arabidopsis basic/helix-loop-helix transcription factor family.

Q96QU1	PCD15_HUMAN	Protocadherin-15	11398101	Mutations of the protocadherin gene PCDH15 cause Usher syndrome type 1F.

P53949	OCA2_YEAST	Tyrosine-protein phosphatase-like protein OCA2	14562095	Global analysis of protein localization in budding yeast.

P17535	JUND_HUMAN	Transcription factor jun-D	1903194	Structure and function of human jun-D.

P32829	MRE11_YEAST	Double-strand break repair protein MRE11	7789757	Interaction of Mre11 and Rad50: two proteins required for DNA repair and meiosis-specific double-strand break formation in Saccharomyces cerevisiae.

Q5EE38	ACD_MOUSE	Adrenocortical dysplasia protein	19648609	OB fold-containing protein 1 (OBFC1), a human homolog of yeast Stn1, associates with TPP1 and is implicated in telomere length regulation.

Q6NVD0	FREM2_MOUSE	FRAS1-related extracellular matrix protein 2	15838507	Identification of a new gene mutated in Fraser syndrome and mouse myelencephalic blebs.

O95433	AHSA1_HUMAN	Activator of 90 kDa heat shock protein ATPase homolog 1	16696853	A yeast 2-hybrid analysis of human GTP cyclohydrolase I protein interactions.

P62762	VISL1_RAT	Visinin-like protein 1	1375457	cDNA cloning of a neural visinin-like Ca(2+)-binding protein.

P53010	PAN2_YEAST	PAB-dependent poly(A)-specific ribonuclease subunit PAN2	8550599	The yeast Pan2 protein is required for poly(A)-binding protein- stimulated poly(A)-nuclease activity.

P37747	GLF_ECOLI	UDP-galactopyranose mutase	8576037	Galactofuranose biosynthesis in Escherichia coli K-12: identification and cloning of UDP-galactopyranose mutase.

Q9EPW0	INP4A_MOUSE	Type I inositol-3,4-bisphosphate 4-phosphatase	11087841	Inositol polyphosphate 4-phosphatase type I regulates cell growth downstream of transcription factor GATA-1.

Q54BX4	HSSA_DICDI	Protein hssA	18204858	GBF-dependent family genes morphologically suppress the partially active Dictyostelium STATa strain.

Q9VCZ3	OCTB1_DROME	Octopamine receptor beta-1R	15998303	Identification and characterization of a novel family of Drosophila beta-adrenergic-like octopamine G-protein coupled receptors.

P43583	BLM10_YEAST	Proteasome activator BLM10	15778719	The HEAT repeat protein Blm10 regulates the yeast proteasome by capping the core particle.

Q15543	TAF13_HUMAN	Transcription initiation factor TFIID subunit 13	9695952	Human TAF(II)28 and TAF(II)18 interact through a histone fold encoded by atypical evolutionary conserved motifs also found in the SPT3 family.

P55039	DRG2_HUMAN	Developmentally-regulated GTP-binding protein 2	7929244	A novel GTP-binding protein which is selectively repressed in SV40 transformed fibroblasts.

Q7TSY6	CELF4_MOUSE	CUGBP Elav-like family member 4	11158314	The CELF family of RNA binding proteins is implicated in cell- specific and developmentally regulated alternative splicing.

P25353	NPP1_YEAST	Ectonucleotide pyrophosphatase/phosphodiesterase 1	16278456	Pho5p and newly identified nucleotide pyrophosphatases/ phosphodiesterases regulate extracellular nucleotide phosphate metabolism in Saccharomyces cerevisiae.

P32634	PMD1_YEAST	Negative regulator of sporulation PMD1	14562095	Global analysis of protein localization in budding yeast.

Q15750	TAB1_HUMAN	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1	8638164	TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction.

Q3TDN0	DISP1_MOUSE	Protein dispatched homolog 1	12421714	Mouse dispatched mutants fail to distribute hedgehog proteins and are defective in hedgehog signaling.

Q6P5Z2	PKN3_HUMAN	Serine/threonine-protein kinase N3	10441506	Identification and characterization of PKNbeta, a novel isoform of protein kinase PKN: expression and arachidonic acid dependency are different from those of PKNalpha.

P50111	ZDS1_YEAST	Protein ZDS1	11134339	Nucleocytoplasmic distribution of budding yeast protein kinase A regulatory subunit Bcy1 requires Zds1 and is regulated by Yak1- dependent phosphorylation of its targeting domain.

Q8NG31	CASC5_HUMAN	Protein CASC5	15579588	The protein encoded by cancer/testis gene D40/AF15q14 is localized in spermatocytes, acrosomes of spermatids and ejaculated spermatozoa.

O08623	SQSTM_RAT	Sequestosome-1	12431995	ZIP3, a new splice variant of the PKC-zeta-interacting protein family, binds to GABAC receptors, PKC-zeta, and Kv beta 2.

O74342	YH2B_SCHPO	Uncharacterized protein C1A4.11c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O75529	TAF5L_HUMAN	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L	9674425	Histone-like TAFs within the PCAF histone acetylase complex.

Q13255	GRM1_HUMAN	Metabotropic glutamate receptor 1	7476890	Cloning and expression of a human metabotropic glutamate receptor 1 alpha: enhanced coupling on co-transfection with a glutamate transporter.

Q9V730	EXT1_DROME	Exostosin-1	10806213	Structural analysis of glycosaminoglycans in animals bearing mutations in sugarless, sulfateless, and tout-velu. Drosophila homologues of vertebrate genes encoding glycosaminoglycan biosynthetic enzymes.

Q06787	FMR1_HUMAN	Fragile X mental retardation 1 protein	12837692	82-FIP, a novel FMRP (fragile X mental retardation protein) interacting protein, shows a cell cycle-dependent intracellular localization.

Q9LPG6	RHM2_ARATH	Probable rhamnose biosynthetic enzyme 2	14671019	RHM2 is involved in mucilage pectin synthesis and is required for the development of the seed coat in Arabidopsis.

Q12748	CTF3_YEAST	Central kinetochore subunit CTF3	11782448	Ctf3p, the Mis6 budding yeast homolog, interacts with Mcm22p and Mcm16p at the yeast outer kinetochore.

O94868	FCSD2_HUMAN	FCH and double SH3 domains protein 2	14627983	Carom: a novel membrane-associated guanylate kinase-interacting protein with two SH3 domains.

Q84Y95	GRS14_ARATH	Monothiol glutaredoxin-S14, chloroplastic	16829529	AtGRXcp, an Arabidopsis chloroplastic glutaredoxin, is critical for protection against protein oxidative damage.

P31414	AVP1_ARATH	Pyrophosphate-energized vacuolar membrane proton pump 1	16210544	Arabidopsis H(+)-PPase AVP1 regulates auxin-mediated organ development.

P39962	KC13_YEAST	Casein kinase I homolog 3	14668479	The yeast casein kinase Yck3p is palmitoylated, then sorted to the vacuolar membrane with AP-3-dependent recognition of a YXXPhi adaptin sorting signal.

Q9EPB8	V1R54_MOUSE	Vomeronasal type-1 receptor 54	11116090	Sequence diversity and genomic organization of vomeronasal receptor genes in the mouse.

P48558	YN45_YEAST	Uncharacterized vacuolar membrane protein YNL305C	14562095	Global analysis of protein localization in budding yeast.

Q9V9W8	PYGO_DROME	Protein pygopus	11955446	Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex.

Q54DF9	DCUP_DICDI	Uroporphyrinogen decarboxylase	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P35580	MYH10_HUMAN	Myosin-10	7499478	Cloning of the cDNA encoding human nonmuscle myosin heavy chain-B and analysis of human tissues with isoform-specific antibodies.

Q08649	ESA1_YEAST	Histone acetyltransferase ESA1	15045029	A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin.

Q9UTE3	SEB1_SCHPO	Rpb7-binding protein seb1	12907709	Rpb7 subunit of RNA polymerase II interacts with an RNA-binding protein involved in processing of transcripts.

P22561	WT1_MOUSE	Wilms tumor protein homolog	16467207	Wilms tumor suppressor, Wt1, is a transcriptional activator of the erythropoietin gene.

P07320	CRGD_HUMAN	Gamma-crystallin D	12676897	Gamma-D crystallin gene (CRYGD) mutation causes autosomal dominant congenital cerulean cataracts.

Q80VM9	OTOP1_MOUSE	Otopetrin-1	12651873	Non-syndromic vestibular disorder with otoconial agenesis in tilted/mergulhador mice caused by mutations in otopetrin 1.

P67809	YBOX1_HUMAN	Nuclease-sensitive element-binding protein 1	2977358	Two human genes isolated by a novel method encode DNA-binding proteins containing a common region of homology.

P09615	WNTG_DROME	Protein wingless	11821428	Drosophila segment polarity gene product porcupine stimulates the posttranslational N-glycosylation of wingless in the endoplasmic reticulum.

O94427	MU167_SCHPO	Meiotically up-regulated gene 167 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O94646	MED8_SCHPO	Mediator of RNA polymerase II transcription subunit 8	11572939	Analysis of Schizosaccharomyces pombe mediator reveals a set of essential subunits conserved between yeast and metazoan cells.

O88491	NSD1_MOUSE	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific	9628876	Two distinct nuclear receptor interaction domains in NSD1, a novel SET protein that exhibits characteristics of both corepressors and coactivators.

P06911	LCN5_RAT	Epididymal-specific lipocalin-5	2125511	An 18-kDa androgen-regulated protein that modifies galactosyltransferase activity is synthesized by the rat caput epididymidis, but has no structural similarity to rat milk alphalactalbumin.

P11927	KAR1_YEAST	Cell division control protein KAR1	10428957	Interaction of the yeast gamma-tubulin complex-binding protein Spc72p with Kar1p is essential for microtubule function during karyogamy.

Q06628	ATG13_YEAST	Autophagy-related protein 13	10837477	Apg13p and Vac8p are part of a complex of phosphoproteins that are required for cytoplasm to vacuole targeting.

P48965	MPIP1_RAT	M-phase inducer phosphatase 1	8156993	Cdc25A is a novel phosphatase functioning early in the cell cycle.

Q9R1B9	SLIT2_MOUSE	Slit homolog 2 protein	12097499	Slit1 and slit2 proteins control the development of the lateral olfactory tract.

P47019	ALB1_YEAST	Ribosome biogenesis protein ALB1	16651379	A functional network involved in the recycling of nucleocytoplasmic pre-60S factors.

Q9Z0X0	BORG3_MOUSE	Cdc42 effector protein 5	11035016	A new family of Cdc42 effector proteins, CEPs, function in fibroblast and epithelial cell shape changes.

O13023	HHEX_XENLA	Hematopoietically-expressed homeobox protein hhex	16936074	Hex acts with beta-catenin to regulate anteroposterior patterning via a Groucho-related co-repressor and Nodal.

Q02763	TIE2_HUMAN	Angiopoietin-1 receptor	8382358	Molecular cloning and characterization of a novel receptor protein tyrosine kinase from human placenta.

P40319	ELO3_YEAST	Elongation of fatty acids protein 3	9211877	ELO2 and ELO3, homologues of the Saccharomyces cerevisiae ELO1 gene, function in fatty acid elongation and are required for sphingolipid formation.

Q9ZR12	GRH1_ARATH	GRR1-like protein 1	12008900	Cloning by pathway activation in yeast: identification of an Arabidopsis thaliana F-box protein that can turn on glucose repression.

Q99996	AKAP9_HUMAN	A-kinase anchor protein 9	10202149	Cloning and characterization of a cDNA encoding an A-kinase anchoring protein located in the centrosome, AKAP450.

Q5D1Z3	NOL12_RAT	Nucleolar protein 12	16430885	Molecular cloning and characterization of Nop25, a novel nucleolar RNA binding protein, highly conserved in vertebrate species.

O74324	YH04_SCHPO	Uncharacterized protein C1685.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q16637	SMN_HUMAN	Survival motor neuron protein	9323129	The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins.

Q9HGK9	YHLD_SCHPO	Uncharacterized protein C800.13	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

Q7Z4N2	TRPM1_HUMAN	Transient receptor potential cation channel subfamily M member 1	19896109	Mutations in TRPM1 are a common cause of complete congenital stationary night blindness.

Q91550	ILF3A_XENLA	Interleukin enhancer-binding factor 3-A	15452137	Intact RNA-binding domains are necessary for structure-specific DNA binding and transcription control by CBTF122 during Xenopus development.

P54843	MAF_MOUSE	Transcription factor Maf	10383433	Regulation of lens fiber cell differentiation by transcription factor c-Maf.

Q16670	ZN187_HUMAN	Zinc finger protein 187	1569959	Expression cloning of a novel zinc finger protein that binds to the c-fos serum response element.

P41930	SSU1_YEAST	Sulfite efflux pump SSU1	10870099	SSU1 mediates sulphite efflux in Saccharomyces cerevisiae.

P25098	ARBK1_HUMAN	Beta-adrenergic receptor kinase 1	1339451	High expression of beta-adrenergic receptor kinase in human peripheral blood leukocytes. Isoproterenol and platelet activating factor can induce kinase translocation.

Q05783	HMGD_DROME	High mobility group protein D	8168480	HMG-D, the Drosophila melanogaster homologue of HMG 1 protein, is associated with early embryonic chromatin in the absence of histone H1.

Q9BSG0	PAP21_HUMAN	Protease-associated domain-containing protein of 21 kDa	15498570	N-glycosylation is required for efficient secretion of a novel human secreted glycoprotein, hPAP21.

P32586	PYP2_SCHPO	Tyrosine-protein phosphatase 2	1464319	Negative regulation of mitosis by two functionally overlapping PTPases in fission yeast.

P49186	MK09_RAT	Mitogen-activated protein kinase 9	10856240	The evi-1 oncoprotein inhibits c-Jun N-terminal kinase and prevents stress-induced cell death.

Q9H3M0	KCNF1_HUMAN	Potassium voltage-gated channel subfamily F member 1	9434767	Isolation, characterization, and mapping of two human potassium channels.

P11747	TAF13_YEAST	Transcription initiation factor TFIID subunit 13	12138208	Molecular characterization of Saccharomyces cerevisiae TFIID.

P46998	FMP33_YEAST	Mitochondrial membrane protein FMP33	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P24813	YAP2_YEAST	AP-1-like transcription activator YAP2	8360174	Yeast bZip proteins mediate pleiotropic drug and metal resistance.

P47075	VTC4_YEAST	Vacuolar transporter chaperone 4	11823419	The Vtc proteins in vacuole fusion: coupling NSF activity to V(0) trans-complex formation.

Q9JM93	AR6P4_MOUSE	ADP-ribosylation factor-like protein 6-interacting protein 4	10508919	A novel ADP-ribosylation like factor (ARL-6), interacts with the protein-conducting channel SEC61beta subunit.

O14179	SDO1_SCHPO	Ribosome maturation protein sdo1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9V6G5	TAZ_DROME	Tafazzin homolog	16855048	A Drosophila model of Barth syndrome.

P53833	POP3_YEAST	Ribonucleases P/MRP protein subunit POP3	9620854	Purification and characterization of the nuclear RNase P holoenzyme complex reveals extensive subunit overlap with RNase MRP.

Q9LQ98	AFP1_ARATH	Ninja-family protein AFP1	12569131	AFP is a novel negative regulator of ABA signaling that promotes ABI5 protein degradation.

P51113	FMR1A_XENLA	Fragile X mental retardation protein 1 homolog A	7781595	FXR1, an autosomal homolog of the fragile X mental retardation gene.

P41279	M3K8_HUMAN	Mitogen-activated protein kinase kinase kinase 8	15169888	ABIN-2 forms a ternary complex with TPL-2 and NF-kappa B1 p105 and is essential for TPL-2 protein stability.

P0A7Q1	RL35_ECOLI	50S ribosomal protein L35	3298224	Primary structures of and genes for new ribosomal proteins A and B in Escherichia coli.

P53148	SP105_YEAST	Spindle pole body component SPC105	14565975	Interactions between centromere complexes in Saccharomyces cerevisiae.

Q10256	MUD1_SCHPO	UBA domain-containing protein mud1	11584278	Proteins containing the UBA domain are able to bind to multi- ubiquitin chains.

Q9NA26	VPS28_CAEEL	Vacuolar protein sorting-associated protein 28 homolog	15998324	CeVPS-27 is an endosomal protein required for the molting and the endocytic trafficking of the low-density lipoprotein receptor-related protein 1 in Caenorhabditis elegans.

Q8NEU8	DP13B_HUMAN	DCC-interacting protein 13-beta	15016378	APPL proteins link Rab5 to nuclear signal transduction via an endosomal compartment.

Q9UGQ3	GTR6_HUMAN	Solute carrier family 2, facilitated glucose transporter member 6	10970791	Activity and genomic organization of human glucose transporter 9 (GLUT9), a novel member of the family of sugar-transport facilitators predominantly expressed in brain and leucocytes.

Q16445	GBRA6_HUMAN	Gamma-aminobutyric acid receptor subunit alpha-6	8632757	Cloning of cDNAs encoding the human gamma-aminobutyric acid type A receptor alpha 6 subunit and characterization of the pharmacology of alpha 6-containing receptors.

Q64096	MCF2L_MOUSE	Guanine nucleotide exchange factor DBS	11889037	A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange.

Q9JKQ4	IRX5_MOUSE	Iroquois-class homeodomain protein IRX-5	18322081	Genetic control of circuit function: Vsx1 and Irx5 transcription factors regulate contrast adaptation in the mouse retina.

P12843	IBP2_RAT	Insulin-like growth factor-binding protein 2	2538475	Nucleotide sequence and expression of a cDNA clone encoding a fetal rat binding protein for insulin-like growth factors.

P05155	IC1_HUMAN	Plasma protease C1 inhibitor	10946292	Proteolytic activities of two types of mannose-binding lectin- associated serine protease.

Q92560	BAP1_HUMAN	Ubiquitin carboxyl-terminal hydrolase BAP1	19188440	Association of C-terminal ubiquitin hydrolase BRCA1-associated protein 1 with cell cycle regulator host cell factor 1.

O42998	YBC8_SCHPO	Uncharacterized protein C27B12.08	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8IBG1	DYHC1_PLAF7	Dynein heavy chain-like protein MAL7P1.162	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

P34217	PIN4_YEAST	RNA-binding protein PIN4	15024067	Mdt1, a novel Rad53 FHA1 domain-interacting protein, modulates DNA damage tolerance and G(2)/M cell cycle progression in Saccharomyces cerevisiae.

Q07488	BCB1_ARATH	Blue copper protein	8294044	A negatively light-regulated gene from Arabidopsis thaliana encodes a protein showing high similarity to blue copper-binding proteins.

P13803	ETFA_RAT	Electron transfer flavoprotein subunit alpha, mitochondrial	3415685	Molecular cloning of a cDNA for alpha-subunit of rat liver electron transfer flavoprotein.

Q01344	IL5RA_HUMAN	Interleukin-5 receptor subunit alpha	1495999	Molecular basis of the membrane-anchored and two soluble isoforms of the human interleukin 5 receptor alpha subunit.

O60231	DHX16_HUMAN	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16	9547260	Cloning and characterization of a human DEAH-box RNA helicase, a functional homolog of fission yeast Cdc28/Prp8.

Q43725	CYSKM_ARATH	Cysteine synthase, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

O46077	OR2A_DROME	Odorant receptor 2a	10069338	A novel family of divergent seven-transmembrane proteins: candidate odorant receptors in Drosophila.

Q27237	TID_DROME	Protein tumorous imaginal discs, mitochondrial	9585178	Mitochondrial localization and temporal expression of the Drosophila melanogaster DnaJ homologous tumor suppressor Tid50.

Q9HC62	SENP2_HUMAN	Sentrin-specific protease 2	11896061	Association of the human SUMO-1 protease SENP2 with the nuclear pore.

Q9P7G6	YK42_SCHPO	Transcription factor P14E8.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q92833	JARD2_HUMAN	Protein Jumonji	8894700	Characterization of the human jumonji gene.

Q9UBV8	PEF1_HUMAN	Peflin	11883899	Both ALG-2 and peflin, penta-EF-hand (PEF) proteins, are stabilized by dimerization through their fifth EF-hand regions.

P84812	MPHES_MICSP	Monoalkyl phthalate esterase	15713880	Purification and characterization of an esterase hydrolyzing monoalkyl phthalates from Micrococcus sp. YGJ1.

O75333	TBX10_HUMAN	T-box transcription factor TBX10	9545502	TBX10, a member of the Tbx1-subfamily of conserved developmental genes, is located at human chromosome 11q13 and proximal mouse chromosome 19.

P12844	MYO3_CAEEL	Myosin-3	2583106	The minor myosin heavy chain, mhcA, of Caenorhabditis elegans is necessary for the initiation of thick filament assembly.

Q54VG4	SGT_DICDI	Small glutamine-rich tetratricopeptide repeat-containing protein	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

O43291	SPIT2_HUMAN	Kunitz-type protease inhibitor 2	9346890	Purification and cloning of hepatocyte growth factor activator inhibitor type 2, a Kunitz-type serine protease inhibitor.

P32336	NUD1_YEAST	Protein NUD1	9585415	Analysis of the Saccharomyces spindle pole by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry.

O75460	ERN1_HUMAN	Serine/threonine-protein kinase/endoribonuclease IRE1	9637683	A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells.

Q93VY3	NAC72_ARATH	NAC domain-containing protein 72	16581911	Transcriptional and posttranscriptional regulation of transcription factor expression in Arabidopsis roots.

Q03921	DOP1_YEAST	Protein dopey	10931277	Morphogenesis in Aspergillus nidulans requires Dopey (DopA), a member of a novel family of leucine zipper-like proteins conserved from yeast to humans.

P98192	GNPAT_MOUSE	Dihydroxyacetone phosphate acyltransferase	10395968	Identification and characterization of the mouse cDNA encoding acyl- CoA:dihydroxyacetone phosphate acyltransferase.

Q9H0M0	WWP1_HUMAN	NEDD4-like E3 ubiquitin-protein ligase WWP1	9647693	Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins.

Q93655	NAD1_CAEEL	Sodium-dependent low-affinity dicarboxylate transporter 1	12480943	Structural and functional characteristics of two sodium-coupled dicarboxylate transporters (ceNaDC1 and ceNaDC2) from Caenorhabditis elegans and their relevance to life span.

P13584	CP4B1_HUMAN	Cytochrome P450 4B1	2574990	Identification of a new P450 expressed in human lung: complete cDNA sequence, cDNA-directed expression, and chromosome mapping.

P39676	FHP_YEAST	Flavohemoprotein	10758168	Protection from nitrosative stress by yeast flavohemoglobin.

Q04806	GTO3_YEAST	Glutathione S-transferase omega-like 3	16709151	Saccharomyces cerevisiae cells have three Omega class glutathione S- transferases acting as 1-Cys thiol transferases.

Q8LE52	DHAR3_ARATH	Glutathione S-transferase DHAR3, chloroplastic	12938931	Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis.

Q9GZV4	IF5A2_HUMAN	Eukaryotic translation initiation factor 5A-2	11161802	Human eIF5A2 on chromosome 3q25-q27 is a phylogenetically conserved vertebrate variant of eukaryotic translation initiation factor 5A with tissue-specific expression.

Q02197	NAA35_YEAST	N-alpha-acetyltransferase, 35 NatC auxiliary subunit	11274203	NatC Nalpha-terminal acetyltransferase of yeast contains three subunits, Mak3p, Mak10p, and Mak31p.

Q9QXU7	PROK2_MOUSE	Prokineticin-2	12024206	Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus.

Q9S758	SPL5_ARATH	Squamosa promoter-binding-like protein 5	16914499	Temporal regulation of shoot development in Arabidopsis thaliana by miR156 and its target SPL3.

Q9BT67	NFIP1_HUMAN	NEDD4 family-interacting protein 1	18776082	Regulation of the divalent metal ion transporter DMT1 and iron homeostasis by a ubiquitin-dependent mechanism involving Ndfips and WWP2.

Q9BS18	APC13_HUMAN	Anaphase-promoting complex subunit 13	16364912	Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C.

P37702	BGL38_ARATH	Myrosinase 1	7766881	The myrosinase gene family in Arabidopsis thaliana: gene organization, expression and evolution.

P25864	RK9_ARATH	50S ribosomal protein L9, chloroplastic	1581570	Characterization of rps17, rp19 and rpl15: three nucleus-encoded plastid ribosomal protein genes.

P53701	CCHL_HUMAN	Cytochrome c-type heme lyase	8661044	Cloning and characterization of a putative human holocytochrome c- type synthetase gene (HCCS) isolated from the critical region for microphthalmia with linear skin defects (MLS).

P42073	REF2_YEAST	RNA end formation protein 2	12773397	Pti1p and Ref2p found in association with the mRNA 3' end formation complex direct snoRNA maturation.

P15382	KCNE1_HUMAN	Potassium voltage-gated channel subfamily E member 1	9354802	Mutations in the hminK gene cause long QT syndrome and suppress IKs function.

Q60674	NR1D2_MOUSE	Nuclear receptor subfamily 1 group D member 2	7838158	Cross-talk among ROR alpha 1 and the Rev-erb family of orphan nuclear receptors.

Q24572	CAF1_DROME	Probable histone-binding protein Caf1	9784495	Inorganic pyrophosphatase is a component of the Drosophila nucleosome remodeling factor complex.

Q9UFH2	DYH17_HUMAN	Dynein heavy chain 17, axonemal	9373155	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

P35226	BMI1_HUMAN	Polycomb complex protein BMI-1	16714294	Structure of a Bmi-1-Ring1B polycomb group ubiquitin ligase complex.

P0A749	MURA_ECOLI	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	1512209	Cloning and sequencing of Escherichia coli murZ and purification of its product, a UDP-N-acetylglucosamine enolpyruvyl transferase.

Q09684	KAR5_SCHPO	Nuclear fusion protein tht1	9442101	A novel fission yeast gene, tht1+, is required for the fusion of nuclear envelopes during karyogamy.

Q15835	RK_HUMAN	Rhodopsin kinase	9147475	Molecular cloning and localization of rhodopsin kinase in the mammalian pineal.

Q09858	NNF1_SCHPO	Kinetochore protein nnf1	17035632	Reconstruction of the kinetochore during meiosis in fission yeast Schizosaccharomyces pombe.

Q9BZV2	S19A3_HUMAN	Thiamine transporter 2	11136550	Identification and characterization of the human and mouse SLC19A3 gene: a novel member of the reduced folate family of micronutrient transporter genes.

Q8CBW3	ABI1_MOUSE	Abl interactor 1	7590237	Abl-interactor-1, a novel SH3 protein binding to the carboxy-terminal portion of the Abl protein, suppresses v-abl transforming activity.

Q94F39	AFP3_ARATH	Ninja-family protein AFP3	18484180	A small plant-specific protein family of ABI five binding proteins (AFPs) regulates stress response in germinating Arabidopsis seeds and seedlings.

Q4LBB6	OCTB3_DROME	Octopamine receptor beta-3R	15998303	Identification and characterization of a novel family of Drosophila beta-adrenergic-like octopamine G-protein coupled receptors.

Q8N6I1	EID2_HUMAN	EP300-interacting inhibitor of differentiation 2	14612439	A novel E1A-like inhibitor of differentiation (EID) family member, EID-2, suppresses transforming growth factor (TGF)-beta signaling by blocking TGF-beta-induced formation of Smad3-Smad4 complexes.

Q86B87	MMD4_DROME	Modifier of mdg4	9111355	Doom, a product of the Drosophila mod(mdg4) gene, induces apoptosis and binds to baculovirus inhibitor-of-apoptosis proteins.

P46482	AAEA_ECOLI	p-hydroxybenzoic acid efflux pump subunit AaeA	15489430	Characterization of the Escherichia coli AaeAB efflux pump: a metabolic relief valve?

Q3LUD4	LZTS2_RAT	Leucine zipper putative tumor suppressor 2	17351128	LAPSER1 is a putative cytokinetic tumor suppressor that shows the same centrosome and midbody subcellular localization pattern as p80 katanin.

P48994	TRPL_DROME	Transient-receptor-potential-like protein	9494079	The role of calmodulin-binding sites in the regulation of the Drosophila TRPL cation channel expressed in Xenopus laevis oocytes by ca2+, inositol 1,4,5-trisphosphate and GTP-binding proteins.

P84995	GANOD_GANLU	Ganodermin	16039755	Ganodermin, an antifungal protein from fruiting bodies of the medicinal mushroom Ganoderma lucidum.

P93030	RMA2_ARATH	E3 ubiquitin-protein ligase RMA2	20152813	In vitro and in vivo interaction of AtRma2 E3 ubiquitin ligase and auxin-binding protein 1.

Q9UUZ3	MANBA_ASPNG	Beta-mannosidase	11358516	Cloning and characterization of Aspergillus niger genes encoding an alpha-galactosidase and a beta-mannosidase involved in galactomannan degradation.

Q01112	CDC42_SCHPO	Cell division control protein 42 homolog	12529446	Gef1p, a new guanine nucleotide exchange factor for Cdc42p, regulates polarity in Schizosaccharomyces pombe.

Q8GTR4	PULA1_ARATH	Pullulanase 1, chloroplastic	18815382	Further evidence for the mandatory nature of polysaccharide debranching for the aggregation of semicrystalline starch and for overlapping functions of debranching enzymes in Arabidopsis leaves.

Q8RWN7	P2C32_ARATH	Protein phosphatase 2C 32	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

P17026	ZNF22_HUMAN	Zinc finger protein 22	1946370	Characterization and mapping of human genes encoding zinc finger proteins.

Q9NSA0	S22AB_HUMAN	Solute carrier family 22 member 11	15102942	The role of glycine residues in the function of human organic anion transporter 4.

O60506	HNRPQ_HUMAN	Heterogeneous nuclear ribonucleoprotein Q	9847309	A novel heterogeneous nuclear ribonucleoprotein-like protein interacts with NS1 of the minute virus of mice.

P15311	EZRI_HUMAN	Ezrin	12651155	PACE-1, a novel protein that interacts with the C-terminal domain of ezrin.

P01011	AACT_HUMAN	Alpha-1-antichymotrypsin	2404007	Cloning, expression, purification, and biological activity of recombinant native and variant human alpha 1-antichymotrypsins.

P20484	MAK11_YEAST	Protein MAK11	7739558	Yeast virus propagation depends critically on free 60S ribosomal subunit concentration.

Q71TY3	RS27_RAT	40S ribosomal protein S27	10820185	Evolutionarily distinct classes of S27 ribosomal proteins with differential mRNA expression in rat hypothalamus.

Q9HB21	PKHA1_HUMAN	Pleckstrin homology domain-containing family A member 1	11001876	Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities.

Q9Z1T5	DEAF1_MOUSE	Deformed epidermal autoregulatory factor 1 homolog	14966286	Defective neural tube closure and anteroposterior patterning in mice lacking the LIM protein LMO4 or its interacting partner Deaf-1.

Q9GZM7	TINAL_HUMAN	Tubulointerstitial nephritis antigen-like	11170462	TIN-ag-RP, a novel catalytically inactive cathepsin B-related protein with EGF domains, is predominantly expressed in vascular smooth muscle cells.

O76076	WISP2_HUMAN	WNT1-inducible-signaling pathway protein 2	9843955	WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors.

Q21921	SIRT1_CAEEL	NAD-dependent deacetylase SIR2 homolog	11242085	Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans.

Q08645	FOLE_YEAST	Folylpolyglutamate synthase	10775416	Disruption of cytoplasmic and mitochondrial folylpolyglutamate synthetase activity in Saccharomyces cerevisiae.

O82132	DRE2A_ARATH	Dehydration-responsive element-binding protein 2A	9707537	Two transcription factors, DREB1 and DREB2, with an EREBP/AP2 DNA binding domain separate two cellular signal transduction pathways in drought- and low-temperature-responsive gene expression, respectively, in Arabidopsis.

P47133	EMC2_YEAST	ER membrane protein complex subunit 2	19325107	Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum.

O94601	YC8E_SCHPO	Uncharacterized protein C622.14	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12010	YO092_YEAST	Uncharacterized membrane protein YOL092W	14562095	Global analysis of protein localization in budding yeast.

O94246	GSH0_SCHPO	Putative glutamate--cysteine ligase regulatory subunit	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q08851	STX5_RAT	Syntaxin-5	9307973	An isoform of the Golgi t-SNARE, syntaxin 5, with an endoplasmic reticulum retrieval signal.

Q9NRD0	FBX8_HUMAN	F-box only protein 8	10945468	cDNA cloning and expression analysis of new members of the mammalian F-box protein family.

O94330	NAGS_SCHPO	Amino-acid acetyltransferase, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P0ABU0	MENB_ECOLI	Naphthoate synthase	1629162	Menaquinone (vitamin K2) biosynthesis: nucleotide sequence and expression of the menB gene from Escherichia coli.

P60210	KAX44_TITCA	Potassium channel toxin alpha-KTx 4.4	12445473	Two novel toxins from the Amazonian scorpion Tityus cambridgei that block Kv1.3 and Shaker B K(+)-channels with distinctly different affinities.

Q03938	ZNF90_HUMAN	Zinc finger protein 90	2023909	The evolutionarily conserved Kruppel-associated box domain defines a subfamily of eukaryotic multifingered proteins.

Q92900	RENT1_HUMAN	Regulator of nonsense transcripts 1	9064659	Cloning and characterization of HUPF1, a human homolog of the Saccharomyces cerevisiae nonsense mRNA-reducing UPF1 protein.

P22061	PIMT_HUMAN	Protein-L-isoaspartate(D-aspartate) O-methyltransferase	1339271	Alternative splicing of the human isoaspartyl protein carboxyl methyltransferase RNA leads to the generation of a C-terminal -RDEL sequence in isozyme II.

P24868	CG21_YEAST	G2/mitotic-specific cyclin-1	1849458	A cyclin B homolog in S. cerevisiae: chronic activation of the Cdc28 protein kinase by cyclin prevents exit from mitosis.

Q27873	PIMT_CAEEL	Protein-L-isoaspartate O-methyltransferase	7662659	Protein L-isoaspartyl methyltransferase from the nematode Caenorhabditis elegans: genomic structure and substrate specificity.

Q8LBC0	CCT13_ARATH	Cyclin-T1-3	12678503	Novel complexes of cyclin-dependent kinases and a cyclin-like protein from Arabidopsis thaliana with a function unrelated to cell division.

P26449	BUB3_YEAST	Cell cycle arrest protein BUB3	10837255	Complex formation between Mad1p, Bub1p and Bub3p is crucial for spindle checkpoint function.

P36596	FDFT_SCHPO	Squalene synthase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P16070	CD44_HUMAN	CD44 antigen	1922057	Expression of CD44 is repressed in neuroblastoma cells.

P49704	PRP31_YEAST	Pre-mRNA-processing factor 31	10449419	Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6.U5] tri-snRNP.

Q9BSB4	ATGA1_HUMAN	Autophagy-related protein 101	19597335	Atg101, a novel mammalian autophagy protein interacting with Atg13.

P51784	UBP11_HUMAN	Ubiquitin carboxyl-terminal hydrolase 11	8845848	A ubiquitin C-terminal hydrolase gene on the proximal short arm of the X chromosome: implications for X-linked retinal disorders.

P18562	UPP_YEAST	Uracil phosphoribosyltransferase	2189783	The FUR1 gene of Saccharomyces cerevisiae: cloning, structure and expression of wild-type and mutant alleles.

P53720	DUS2_YEAST	tRNA-dihydrouridine synthase 2	14970222	The specificities of four yeast dihydrouridine synthases for cytoplasmic tRNAs.

Q8R4Y8	RTTN_MOUSE	Rotatin	11900971	Rotatin is a novel gene required for axial rotation and left-right specification in mouse embryos.

P39697	RT19_ARATH	40S ribosomal protein S19, mitochondrial	8641279	Transfer of rps19 to the nucleus involves the gain of an RNP-binding motif which may functionally replace RPS13 in Arabidopsis mitochondria.

Q8TDS4	G109A_HUMAN	G-protein coupled receptor 109A	12522134	Molecular identification of high and low affinity receptors for nicotinic acid.

O74309	SLM9_SCHPO	Histone transcription regulator slm9	16428807	Hip3 interacts with the HIRA proteins Hip1 and Slm9 and is required for transcriptional silencing and accurate chromosome segregation.

Q62925	M3K1_RAT	Mitogen-activated protein kinase kinase kinase 1	8643568	Cloning of rat MEK kinase 1 cDNA reveals an endogenous membrane- associated 195-kDa protein with a large regulatory domain.

Q9Y297	FBW1A_HUMAN	F-box/WD repeat-containing protein 1A	12791267	Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase.

Q9SXJ6	CLPP3_ARATH	ATP-dependent Clp protease proteolytic subunit 3, chloroplastic	11278690	Identification of a 350-kDa ClpP protease complex with 10 different Clp isoforms in chloroplasts of Arabidopsis thaliana.

Q95V55	FOXO_DROME	Forkhead box protein O	18234213	dFOXO regulates transcription of a Drosophila acid lipase.

Q15614	OR8G2_HUMAN	Olfactory receptor 8G2	9119360	Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species.

Q9UKN5	PRDM4_HUMAN	PR domain zinc finger protein 4	10552934	PFM1 (PRDM4), a new member of the PR-domain family, maps to a tumor suppressor locus on human chromosome 12q23-q24.1.

P21268	FAR1_YEAST	Cyclin-dependent kinase inhibitor FAR1	2147873	Identification of a gene necessary for cell cycle arrest by a negative growth factor of yeast: FAR1 is an inhibitor of a G1 cyclin, CLN2.

P87027	SPG1_SCHPO	Septum-promoting GTP-binding protein 1	9203579	The Spg1p GTPase is an essential, dosage-dependent inducer of septum formation in Schizosaccharomyces pombe.

P84643	CIRE_CHAPA	Circulin-E	10691702	New circulin macrocyclic polypeptides from Chassalia parvifolia.

P38962	TVP23_YEAST	Golgi apparatus membrane protein TVP23	17178117	Tvp38, Tvp23, Tvp18 and Tvp15: novel membrane proteins in the Tlg2- containing Golgi/endosome compartments of Saccharomyces cerevisiae.

Q9UT09	AROG_SCHPO	Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P38830	NDT80_YEAST	Meiosis-specific transcription factor NDT80	9660952	Gametogenesis in yeast is regulated by a transcriptional cascade dependent on Ndt80.

P33336	SKN1_YEAST	Beta-glucan synthesis-associated protein SKN1	7929594	Characterization of the yeast (1-->6)-beta-glucan biosynthetic components, Kre6p and Skn1p, and genetic interactions between the PKC1 pathway and extracellular matrix assembly.

P68036	UB2L3_HUMAN	Ubiquitin-conjugating enzyme E2 L3	15367689	The ubiquitin-conjugating enzyme UBCH7 acts as a coactivator for steroid hormone receptors.

Q12962	TAF10_HUMAN	Transcription initiation factor TFIID subunit 10	11438666	The TFIID components human TAFII140 and Drosophila BIP2 (TAFII155) are novel metazoan homologues of yeast TAFII47 containing a histone fold and a PHD finger.

P40955	CHS6_YEAST	Chitin biosynthesis protein CHS6	16498409	Arf1p, Chs5p and the ChAPs are required for export of specialized cargo from the Golgi.

P28288	ABCD3_HUMAN	ATP-binding cassette sub-family D member 3	1301993	Mutations in the 70K peroxisomal membrane protein gene in Zellweger syndrome.

Q9VVI2	EDC3_DROME	Enhancer of mRNA-decapping protein 3	17923697	A divergent Sm fold in EDC3 proteins mediates DCP1 binding and P-body targeting.

Q16739	CEGT_HUMAN	Ceramide glucosyltransferase	8643456	Expression cloning of a cDNA for human ceramide glucosyltransferase that catalyzes the first glycosylation step of glycosphingolipid synthesis.

P81895	ODO1_SOLTU	2-oxoglutarate dehydrogenase, mitochondrial	10510296	Plant mitochondrial 2-oxoglutarate dehydrogenase complex: purification and characterization in potato.

Q12252	PHM7_YEAST	Phosphate metabolism protein 7	14562095	Global analysis of protein localization in budding yeast.

Q05080	CYK2_YEAST	Cytokinesis protein 2	9864366	Dual function of Cyk2, a cdc15/PSTPIP family protein, in regulating actomyosin ring dynamics and septin distribution.

P46682	AP3B_YEAST	AP-3 complex subunit beta	9335339	The AP-3 adaptor complex is essential for cargo-selective transport to the yeast vacuole.

O15371	EIF3D_HUMAN	Eukaryotic translation initiation factor 3 subunit D	18599441	Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3.

P43034	LIS1_HUMAN	Platelet-activating factor acetylhydrolase IB subunit alpha	11889140	Role of dynein, dynactin, and CLIP-170 interactions in LIS1 kinetochore function.

O88536	FPR2_MOUSE	Formyl peptide receptor 2	12218158	Identification, cloning, and functional characterization of a murine lipoxin A4 receptor homologue gene.

P53823	SNO2_YEAST	Probable glutamine amidotransferase SNO2	12271461	Functional analysis of yeast gene families involved in metabolism of vitamins B1 and B6.

Q96RL1	UIMC1_HUMAN	BRCA1-A complex subunit RAP80	17525342	Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response.

P40387	TPS1_SCHPO	Alpha,alpha-trehalose-phosphate synthase [UDP-forming]	8021171	Trehalose-6-P synthase is dispensable for growth on glucose but not for spore germination in Schizosaccharomyces pombe.

Q9SEU7	TRXM3_ARATH	Thioredoxin M3, chloroplastic	19218459	Control of Arabidopsis meristem development by thioredoxin-dependent regulation of intercellular transport.

Q08431	MFGM_HUMAN	Lactadherin	8639264	Cloning and sequence analysis of human breast epithelial antigen BA46 reveals an RGD cell adhesion sequence presented on an epidermal growth factor-like domain.

Q1PER6	APX2_ARATH	L-ascorbate peroxidase 2, cytosolic	9144965	Photosynthetic electron transport regulates the expression of cytosolic ascorbate peroxidase genes in Arabidopsis during excess light stress.

P46248	AAT5_ARATH	Aspartate aminotransferase, chloroplastic	7766905	Isolation, characterisation and expression of a cDNA clone encoding plastid aspartate aminotransferase from Arabidopsis thaliana.

P03897	NU3M_HUMAN	NADH-ubiquinone oxidoreductase chain 3	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

O60097	SPT8_SCHPO	Transcription factor spt8	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q86IV5	CTNA_DICDI	Countin-1	10444594	A cell-counting factor regulating structure size in Dictyostelium.

P13693	TCTP_HUMAN	Translationally-controlled tumor protein	15319436	TSAP6 facilitates the secretion of translationally controlled tumor protein/histamine-releasing factor via a nonclassical pathway.

O00762	UBE2C_HUMAN	Ubiquitin-conjugating enzyme E2 C	20061386	The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.

P48664	EAA4_HUMAN	Excitatory amino acid transporter 4	7791878	An excitatory amino-acid transporter with properties of a ligand- gated chloride channel.

Q90435	PO4F3_DANRE	POU domain, class 4, transcription factor 3	15042710	Developmental expression of the POU domain transcription factor Brn- 3b (Pou4f2) in the lateral line and visual system of zebrafish.

P35244	RFA3_HUMAN	Replication protein A 14 kDa subunit	8454588	Cloning, overexpression, and genomic mapping of the 14-kDa subunit of human replication protein A.

Q7TMB8	CYFP1_MOUSE	Cytoplasmic FMR1-interacting protein 1	14765121	Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation.

P47149	NNF1_YEAST	Kinetochore-associated protein NNF1	12455957	Nnf1p, Dsn1p, Mtw1p, and Nsl1p: a new group of proteins important for chromosome segregation in Saccharomyces cerevisiae.

Q9STE8	TC753_ARATH	Protein TOC75-3, chloroplastic	12938931	Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis.

P55317	FOXA1_HUMAN	Hepatocyte nuclear factor 3-alpha	19127412	Role of Foxa1 in regulation of bcl2 expression during oxidative- stress-induced apoptosis in A549 type II pneumocytes.

P16143	PO2F1_XENLA	POU domain, class 2, transcription factor 1	10200537	Non-cell autonomous induction of apoptosis and loss of posterior structures by activation domain-specific interactions of Oct-1 in the Xenopus embryo.

P11458	NADA_ECOLI	Quinolinate synthase A	15898769	Escherichia coli quinolinate synthetase does indeed harbor a [4Fe-4S] cluster.

P40072	SLX8_YEAST	E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX8	18032921	The yeast Slx5-Slx8 DNA integrity complex displays ubiquitin ligase activity.

Q969F1	TF3C6_HUMAN	General transcription factor 3C polypeptide 6	17409385	Identification, molecular cloning, and characterization of the sixth subunit of human transcription factor TFIIIC.

P09936	UCHL1_HUMAN	Ubiquitin carboxyl-terminal hydrolase isozyme L1	12082530	Interaction and colocalization of PGP9.5 with JAB1 and p27(Kip1).

Q8W037	NIP21_ARATH	Aquaporin NIP2-1	16954136	Aquaporin NIP2;1 is mainly localized to the ER membrane and shows root-specific accumulation in Arabidopsis thaliana.

B7ZQJ9	GT2D1_XENLA	General transcription factor II-I repeat domain-containing protein 1	18922797	Oct25 represses transcription of nodal/activin target genes by interaction with signal transducers during Xenopus gastrulation.

O54975	XPP1_RAT	Xaa-Pro aminopeptidase 1	10095056	Cloning and functional expression of the cytoplasmic form of rat aminopeptidase P.

Q96EH5	RL39L_HUMAN	60S ribosomal protein L39-like	12490704	Functional second genes generated by retrotransposition of the X- linked ribosomal protein genes.

Q13546	RIPK1_HUMAN	Receptor-interacting serine/threonine-protein kinase 1	7538908	RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death.

Q8H5T6	LTI6A_ORYSJ	Hydrophobic protein LTI6A	15656983	The OsLti6 genes encoding low-molecular-weight membrane proteins are differentially expressed in rice cultivars with contrasting sensitivity to low temperature.

Q9LKL2	APRR1_ARATH	Two-component response regulator-like APRR1	10926537	Cloning of the Arabidopsis clock gene TOC1, an autoregulatory response regulator homolog.

P78324	SHPS1_HUMAN	Tyrosine-protein phosphatase non-receptor type substrate 1	9062191	A family of proteins that inhibit signalling through tyrosine kinase receptors.

Q9D0K2	SCOT1_MOUSE	Succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial	12534938	Differential expression of succinyl CoA transferase (SCOT) genes in somatic and germline cells of the mouse testis.

O60132	TEA4_SCHPO	Tip elongation aberrant protein Tea4	15936270	Wsh3/Tea4 is a novel cell-end factor essential for bipolar distribution of Tea1 and protects cell polarity under environmental stress in S. pombe.

P10301	RRAS_HUMAN	Ras-related protein R-Ras	16773572	Germline missense mutations affecting KRAS Isoform B are associated with a severe Noonan syndrome phenotype.

P46964	OST2_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2	15831493	Subunits of the translocon interact with components of the oligosaccharyl transferase complex.

P33296	UBC6_YEAST	Ubiquitin-conjugating enzyme E2 6	8396728	A protein translocation defect linked to ubiquitin conjugation at the endoplasmic reticulum.

P09650	MCPT1_RAT	Mast cell protease 1	8996238	Secretory granule proteases in rat mast cells. Cloning of 10 different serine proteases and a carboxypeptidase A from various rat mast cell populations.

Q12952	FOXL1_HUMAN	Forkhead box protein L1	11078474	Mutations in FOXC2 (MFH-1), a forkhead family transcription factor, are responsible for the hereditary lymphedema-distichiasis syndrome.

P32895	KPR1_YEAST	Ribose-phosphate pyrophosphokinase 1	10212224	Genetic analysis and enzyme activity suggest the existence of more than one minimal functional unit capable of synthesizing phosphoribosyl pyrophosphate in Saccharomyces cerevisiae.

Q9BQE5	APOL2_HUMAN	Apolipoprotein L2	11374903	The human apolipoprotein L gene cluster: identification, classification, and sites of distribution.

Q0WX00	RNG1B_ARATH	Putative E3 ubiquitin-protein ligase RING1b	19097900	Polycomb silencing of KNOX genes confines shoot stem cell niches in Arabidopsis.

O22241	AROD4_ARATH	Arogenate dehydratase 4, chloroplastic	19136569	Tyrosine and phenylalanine are synthesized within the plastids in Arabidopsis.

Q9P546	RSSA2_SCHPO	40S ribosomal protein S0-B	14623272	Ribosomal proteins S0 and S21 are involved in the stability of 18S rRNA in fission yeast, Schizosaccharomyces pombe.

Q94AH6	CUL1_ARATH	Cullin-1	10398681	Identification of an SCF ubiquitin-ligase complex required for auxin response in Arabidopsis thaliana.

Q06190	P2R3A_HUMAN	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha	8392071	Structure and expression of a 72-kDa regulatory subunit of protein phosphatase 2A. Evidence for different size forms produced by alternative splicing.

Q9Y8G3	MEX67_SCHPO	mRNA export factor mex67	14963046	Conserved nuclear export sequences in Schizosaccharomyces pombe Mex67 and human TAP function in mRNA export by direct nuclear pore interactions.

P87053	POF1_SCHPO	F-box/WD repeat-containing protein pof1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P14669	ANXA3_RAT	Annexin A3	2968983	Five distinct calcium and phospholipid binding proteins share homology with lipocortin I.

Q9NW08	RPC2_HUMAN	DNA-directed RNA polymerase III subunit RPC2	19609254	RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate.

Q9NPC6	MYOZ2_HUMAN	Myozenin-2	11842093	Calsarcin-3, a novel skeletal muscle-specific member of the calsarcin family, interacts with multiple Z-disc proteins.

O15205	UBD_HUMAN	Ubiquitin D	16495380	Role of ubiquitin-like protein FAT10 in epithelial apoptosis in renal disease.

Q9R1E0	FOXO1_MOUSE	Forkhead box protein O1	17050673	Defects in energy homeostasis in Leigh syndrome French Canadian variant through PGC-1alpha/LRP130 complex.

Q9P3E5	YLZ6_SCHPO	UPF0494 membrane protein C750.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O15392	BIRC5_HUMAN	Baculoviral IAP repeat-containing protein 5	9256286	A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma.

P32795	YME1_YEAST	Mitochondrial inner membrane i-AAA protease supercomplex subunit YME1	16267274	A genomewide screen for petite-negative yeast strains yields a new subunit of the i-AAA protease complex.

Q5Y4Y6	GSDA3_MOUSE	Gasdermin-A3	15475261	The dominant alopecia phenotypes Bareskin, Rex-denuded, and Reduced Coat 2 are caused by mutations in gasdermin 3.

O77059	CRY1_DROME	Cryptochrome-1	10233998	An extraretinally expressed insect cryptochrome with similarity to the blue light photoreceptors of mammals and plants.

P92199	ROCK_CAEEL	Rho-associated protein kinase let-502	11102366	Embryonic morphogenesis in Caenorhabditis elegans integrates the activity of LET-502 Rho-binding kinase, MEL-11 myosin phosphatase, DAF-2 insulin receptor and FEM-2 PP2c phosphatase.

Q12087	RS30_YEAST	40S ribosomal protein S30	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

O14328	KSP1_SCHPO	Serine/threonine-protein kinase ksp1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q09773	MUG62_SCHPO	Meiotically up-regulated gene 62 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q6R2K3	SRF3_ARATH	Protein STRUBBELIG-RECEPTOR FAMILY 3	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P50995	ANX11_HUMAN	Annexin A11	11883939	ALG-2 interacts with the amino-terminal domain of annexin XI in a Ca(2+)-dependent manner.

Q8L799	MIOX1_ARATH	Inositol oxygenase 1	15660207	The inositol oxygenase gene family of Arabidopsis is involved in the biosynthesis of nucleotide sugar precursors for cell-wall matrix polysaccharides.

Q9BZD4	NUF2_HUMAN	Kinetochore protein Nuf2	14699129	Identification of two novel components of the human NDC80 kinetochore complex.

O49482	CADH5_ARATH	Cinnamyl alcohol dehydrogenase 5	12805615	Expression pattern of two paralogs encoding cinnamyl alcohol dehydrogenases in Arabidopsis. Isolation and characterization of the corresponding mutants.

O76460	RAD54_DROME	DNA repair and recombination protein RAD54-like	17660539	A genetic screen for DNA double-strand break repair mutations in Drosophila.

Q39192	SRK2D_ARATH	Serine/threonine-protein kinase SRK2D	17307925	Identification of two protein kinases required for abscisic acid regulation of seed germination, root growth, and gene expression in Arabidopsis.

P20160	CAP7_HUMAN	Azurocidin	1919011	Cloning of the cDNA for the serine protease homolog CAP37/azurocidin, a microbicidal and chemotactic protein from human granulocytes.

Q61169	GATA6_MOUSE	Transcription factor GATA-6	8660897	GATA-6: a zinc finger transcription factor that is expressed in multiple cell lineages derived from lateral mesoderm.

Q50754	HDRC_METTM	CoB--CoM heterodisulfide reductase iron-sulfur subunit C	2121478	Purification and properties of heterodisulfide reductase from Methanobacterium thermoautotrophicum (strain Marburg).

O75161	NPHP4_HUMAN	Nephrocystin-4	12244321	The gene mutated in juvenile nephronophthisis type 4 encodes a novel protein that interacts with nephrocystin.

Q9QZK9	DNS2B_RAT	Deoxyribonuclease-2-beta	10558878	Cloning of a cDNA encoding a rat DNase II-like acid DNase.

P34121	COAA_DICDI	Coactosin	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

Q00960	NMDE2_RAT	Glutamate [NMDA] receptor subunit epsilon-2	19910922	Structure of the zinc-bound amino-terminal domain of the NMDA receptor NR2B subunit.

Q62070	PIM2_MOUSE	Serine/threonine-protein kinase pim-2	17476689	PIM-2 is an independent regulator of chondrocyte survival and autophagy in the epiphyseal growth plate.

Q93074	MED12_HUMAN	Mediator of RNA polymerase II transcription subunit 12	10198638	Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators.

P57678	GEMI4_HUMAN	Component of gems 4	10725331	Gemin4: a novel component of the SMN complex that is found in both gems and nucleoli.

O73823	TAL1_XENLA	T-cell acute lymphocytic leukemia protein 1	11493549	Primitive erythropoiesis in the Xenopus embryo: the synergistic role of LMO-2, SCL and GATA-binding proteins.

O15533	TPSN_HUMAN	Tapasin	9238042	Cloning and functional characterization of a subunit of the transporter associated with antigen processing.

P97605	EFNA5_RAT	Ephrin-A5	7748564	Cloning of AL-1, a ligand for an Eph-related tyrosine kinase receptor involved in axon bundle formation.

Q13591	SEM5A_HUMAN	Semaphorin-5A	15218527	Plexin-B3 is a functional receptor for semaphorin 5A.

Q9P0G3	KLK14_HUMAN	Kallikrein-14	15654974	A proteolytic cascade of kallikreins in the stratum corneum.

Q920C4	MS4A3_MOUSE	Membrane-spanning 4-domains subfamily A member 3	11488981	Cloning and characterization of a mouse homologue of the human haematopoietic cell-specific four-transmembrane gene HTm4.

P09629	HXB7_HUMAN	Homeobox protein Hox-B7	1678287	Lymphoid expression and TATAA binding of a human protein containing an Antennapedia homeodomain.

Q12955	ANK3_HUMAN	Ankyrin-3	15611082	The ammonium transporter RhBG: requirement of a tyrosine-based signal and ankyrin-G for basolateral targeting and membrane anchorage in polarized kidney epithelial cells.

Q26377	CORZ_DROME	Pro-corazonin	12171930	Peptidomics of the larval Drosophila melanogaster central nervous system.

Q673G8	DACT2_DANRE	Dapper homolog 2	15539487	Zebrafish Dapper1 and Dapper2 play distinct roles in Wnt-mediated developmental processes.

P52594	AGFG1_HUMAN	Arf-GAP domain and FG repeats-containing protein 1	7637788	A human nucleoporin-like protein that specifically interacts with HIV Rev.

O14977	AZIN1_HUMAN	Antizyme inhibitor 1	9349715	Cloning and sequencing of a human cDNA encoding ornithine decarboxylase antizyme inhibitor.

Q9FGH4	E139_ARATH	Glucan endo-1,3-beta-glucosidase 9	14517339	Proteomic analysis of glycosylphosphatidylinositol-anchored membrane proteins.

Q9UI33	SCNBA_HUMAN	Sodium channel protein type 11 subunit alpha	10623608	Identification of a novel human voltage-gated sodium channel alpha subunit gene, SCN12A.

Q99614	TTC1_HUMAN	Tetratricopeptide repeat protein 1	8836031	Identification and characterization of two novel tetratricopeptide repeat-containing genes.

Q5BDP1	RSP5_EMENI	E3 ubiquitin-protein ligase RSP5	20002879	Transport-dependent endocytosis and turnover of a uric acid-xanthine permease.

Q9LRM7	NCED6_ARATH	9-cis-epoxycarotenoid dioxygenase NCED6, chloroplastic	12834401	Molecular characterization of the Arabidopsis 9-cis epoxycarotenoid dioxygenase gene family.

Q9S7M2	TI10B_ARATH	Protein TIFY 10B	17637677	JAZ repressor proteins are targets of the SCF(COI1) complex during jasmonate signalling.

O35547	ACSL4_RAT	Long-chain-fatty-acid--CoA ligase 4	9096315	A novel arachidonate-preferring acyl-CoA synthetase is present in steroidogenic cells of the rat adrenal, ovary, and testis.

P41936	HM22_CAEEL	Homeobox protein ceh-22	7925019	The Caenorhabditis elegans NK-2 class homeoprotein CEH-22 is involved in combinatorial activation of gene expression in pharyngeal muscle.

Q9US04	GGT1_SCHPO	Gamma-glutamyltranspeptidase 1	15052323	Characterization and regulation of the gamma-glutamyl transpeptidase gene from the fission yeast Schizosaccharomyces pombe.

P34982	OR1D2_HUMAN	Olfactory receptor 1D2	12663925	Identification of a testicular odorant receptor mediating human sperm chemotaxis.

Q7KNS3	LIS1_DROME	Lissencephaly-1 homolog	16107559	Live imaging of Drosophila brain neuroblasts reveals a role for Lis1/dynactin in spindle assembly and mitotic checkpoint control.

Q99JY1	TIRAP_MOUSE	Toll/interleukin-1 receptor domain-containing adapter protein	11526399	TIRAP: an adapter molecule in the Toll signaling pathway.

Q6F4F5	C724B_ORYSJ	Cytochrome P450 724B1	15705958	A novel cytochrome p450 is implicated in brassinosteroid biosynthesis via the characterization of a rice dwarf mutant, dwarf11, with reduced seed length.

P49005	DPOD2_HUMAN	DNA polymerase delta subunit 2	16510448	Functional roles of p12, the fourth subunit of human DNA polymerase delta.

Q9VZ23	RAN_DROME	GTP-binding nuclear protein Ran	12121620	Ran localizes around the microtubule spindle in vivo during mitosis in Drosophila embryos.

P23291	KC11_YEAST	Casein kinase I homolog 1	1729698	Yeast casein kinase I homologues: an essential gene pair.

Q148B6	SPERI_MOUSE	Speriolin	15280373	Speriolin is a novel spermatogenic cell-specific centrosomal protein associated with the seventh WD motif of Cdc20.

Q99584	S10AD_HUMAN	Protein S100-A13	12746488	S100A13 mediates the copper-dependent stress-induced release of IL- 1alpha from both human U937 and murine NIH 3T3 cells.

O17645	HST2_CAEEL	Heparan sulfate 2-O-sulfotransferase hst-2	12653634	Heparan sulphate sulphotransferase expression in mice and Caenorhabditis elegans.

Q961C9	TNG11_DROME	Transport and Golgi organization protein 11	16452979	Functional genomics reveals genes involved in protein secretion and Golgi organization.

Q7KWQ2	SYSC_DICDI	Seryl-tRNA synthetase, cytoplasmic	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q9BYD5	CNFN_HUMAN	Cornifelin	15147942	Identification and characterization of a novel component of the cornified envelope, cornifelin.

Q9VQS6	DRM_DROME	Protein drumstick	11784087	Drumstick, bowl, and lines are required for patterning and cell rearrangement in the Drosophila embryonic hindgut.

Q9P6N7	ASPGX_SCHPO	Putative L-asparaginase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P35250	RFC2_HUMAN	Replication factor C subunit 2	1313560	Sequence and expression in Escherichia coli of the 40-kDa subunit of activator 1 (replication factor C) of HeLa cells.

P53178	ALG13_YEAST	UDP-N-acetylglucosamine transferase subunit ALG13	14562095	Global analysis of protein localization in budding yeast.

Q95YM8	MBLK1_APIME	Mushroom body large-type Kenyon cell-specific protein 1	11881813	Identification of a novel gene, Mblk-1, that encodes a putative transcription factor expressed preferentially in the large-type Kenyon cells of the honeybee brain.

P10815	CG23_SCHPO	G2/mitotic-specific cyclin cdc13	9303310	p25rum1 promotes proteolysis of the mitotic B-cyclin p56cdc13 during G1 of the fission yeast cell cycle.

P54763	EPHB2_MOUSE	Ephrin type-B receptor 2	11780069	Crystal structure of an Eph receptor-ephrin complex.

Q5W9T5	OPR_OCTVU	Octopressin receptor	15504101	Novel evolutionary lineages of the invertebrate oxytocin/vasopressin superfamily peptides and their receptors in the common octopus (Octopus vulgaris).

Q15751	HERC1_HUMAN	Probable E3 ubiquitin-protein ligase HERC1	8861955	p619, a giant protein related to the chromosome condensation regulator RCC1, stimulates guanine nucleotide exchange on ARF1 and Rab proteins.

P22315	HEMH_MOUSE	Ferrochelatase, mitochondrial	8325637	Ferrochelatase structural mutant (Fechm1Pas) in the house mouse.

Q07938	MEU1_YEAST	Multicopy enhancer of UAS2	8807288	Isolation and identification of genes activating UAS2-dependent ADH2 expression in Saccharomyces cerevisiae.

Q07951	POC3_YEAST	Proteasome chaperone 3	17707236	20S proteasome assembly is orchestrated by two distinct pairs of chaperones in yeast and in mammals.

O14182	RT12_SCHPO	Probable 40S ribosomal protein S12, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P25870	CLH_DICDI	Clathrin heavy chain	8034739	Clathrin heavy chain functions in sorting and secretion of lysosomal enzymes in Dictyostelium discoideum.

Q9M7Q2	AI5L7_ARATH	ABSCISIC ACID-INSENSITIVE 5-like protein 7	11884679	Arabidopsis basic leucine zipper proteins that mediate stress- responsive abscisic acid signaling.

P60953	CDC42_HUMAN	Cell division control protein 42 homolog	10587647	Melanoma chondroitin sulphate proteoglycan regulates cell spreading through Cdc42, Ack-1 and p130cas.

O70418	RN112_RAT	RING finger protein 112	9367872	A novel RING finger protein, BFP, predominantly expressed in the brain.

Q8LPR5	TCP4_ARATH	Transcription factor TCP4	15634699	Genetic and molecular identification of genes required for female gametophyte development and function in Arabidopsis.

Q9BZV1	UBXN6_HUMAN	UBX domain-containing protein 6	18656546	Ubxd1 is a novel co-factor of the human p97 ATPase.

Q9LS42	CASP_ARATH	Protein CASP	16028120	Identification and characterization of AtCASP, a plant transmembrane Golgi matrix protein.

Q15573	TAF1A_HUMAN	TATA box-binding protein-associated factor RNA polymerase I subunit A	7801123	Reconstitution of transcription factor SL1: exclusive binding of TBP by SL1 or TFIID subunits.

O60566	BUB1B_HUMAN	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta	9763420	Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1.

P53687	HST3_YEAST	NAD-dependent histone deacetylase HST3	16815704	The sirtuins Hst3 and Hst4p preserve genome integrity by controlling histone H3 lysine 56 deacetylation.

P02844	VIT2_DROME	Vitellogenin-2	3922974	Tyrosine sulfation of yolk proteins 1, 2, and 3 in Drosophila melanogaster.

P05305	EDN1_HUMAN	Endothelin-1	2649896	The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes.

P62745	RHOB_HUMAN	Rho-related GTP-binding protein RhoB	15226397	Farnesyltransferase inhibitors disrupt EGF receptor traffic through modulation of the RhoB GTPase.

P32600	TOR2_YEAST	Serine/threonine-protein kinase TOR2	16055732	Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarization.

Q9Y371	SHLB1_HUMAN	Endophilin-B1	11161816	SH3GLB, a new endophilin-related protein family featuring an SH3 domain.

Q13228	SBP1_HUMAN	Selenium-binding protein 1	19118533	Human selenium binding protein-1 (hSP56) interacts with VDU1 in a selenium-dependent manner.

Q9FMD7	Y5659_ARATH	Probable inactive receptor kinase At5g16590	17397506	A leucine-rich repeat protein is required for growth promotion and enhanced seed production mediated by the endophytic fungus Piriformospora indica in Arabidopsis thaliana.

Q9ERI2	RB27A_MOUSE	Ras-related protein Rab-27A	18940603	Elucidation of Rab27 recruitment by its effectors: structure of Rab27a bound to Exophilin4/Slp2-a.

Q61327	SC6A3_MOUSE	Sodium-dependent dopamine transporter	19357284	Physical and functional interaction between the dopamine transporter and the synaptic vesicle protein synaptogyrin-3.

Q9BZ11	ADA33_HUMAN	Disintegrin and metalloproteinase domain-containing protein 33	11814695	Identification and characterization of novel mouse and human ADAM33s with potential metalloprotease activity.

P32597	STH1_YEAST	Nuclear protein STH1/NPS1	9121424	Interaction of a Swi3 homolog with Sth1 provides evidence for a Swi/Snf-related complex with an essential function in Saccharomyces cerevisiae.

P0AFE8	NUOM_ECOLI	NADH-quinone oxidoreductase subunit M	15919996	Global topology analysis of the Escherichia coli inner membrane proteome.

P15919	RAG1_MOUSE	V(D)J recombination-activating protein 1	12629039	The RAG1 N-terminal domain is an E3 ubiquitin ligase.

O59671	POF4_SCHPO	Elongin-A	15147268	Molecular interactions of fission yeast Skp1 and its role in the DNA damage checkpoint.

Q9UJX0	OSGI1_HUMAN	Oxidative stress-induced growth inhibitor 1	11459809	Cloning and characterization of a novel pregnancy-induced growth inhibitor in mammary gland.

Q99728	BARD1_HUMAN	BRCA1-associated RING domain protein 1	19261749	NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control.

P0A862	TPX_ECOLI	Thiol peroxidase	7499381	Thioredoxin-linked 'thiol peroxidase' from periplasmic space of Escherichia coli.

Q9FRV1	CHIA_SECCE	Basic endochitinase A	7763659	Purification and some properties of three chitinases from the seeds of rye (Secale cereale).

P30530	UFO_HUMAN	Tyrosine-protein kinase receptor UFO	1656220	AXL, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase.

P43618	CNN1_YEAST	Kinetochore-associated protein CNN1	14562095	Global analysis of protein localization in budding yeast.

Q8TAC9	SCAM5_HUMAN	Secretory carrier-associated membrane protein 5	19234194	Human SCAMP5, a novel secretory carrier membrane protein, facilitates calcium-triggered cytokine secretion by interaction with SNARE machinery.

P83716	HAC8_HALAS	Halocin-C8	12811620	Purification and biological characterization of halocin C8, a novel peptide antibiotic from Halobacterium strain AS7092.

P48380	RFX3_HUMAN	Transcription factor RFX3	8289803	RFX1, a transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins.

P01375	TNFA_HUMAN	Tumor necrosis factor	3883195	Cloning and expression in Escherichia coli of the gene for human tumour necrosis factor.

Q9P7V4	KTI12_SCHPO	Protein kti12	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P32497	EIF3C_YEAST	Eukaryotic translation initiation factor 3 subunit C	1332047	NIP1, a gene required for nuclear transport in yeast.

Q91550	ILF3A_XENLA	Interleukin enhancer-binding factor 3-A	18636753	Methylation of Xilf3 by Xprmt1b alters its DNA, but not RNA, binding activity.

P91682	SMO_DROME	Protein smoothened	8700230	smoothened encodes a receptor-like serpentine protein required for hedgehog signalling.

P11310	ACADM_HUMAN	Medium-chain specific acyl-CoA dehydrogenase, mitochondrial	1731887	Structural organization and regulatory regions of the human medium- chain acyl-CoA dehydrogenase gene.

P52285	SKP1A_DICDI	SCF ubiquitin ligase complex protein SKP1a	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

P48415	SEC16_YEAST	COPII coat assembly protein SEC16	7593161	Yeast SEC16 gene encodes a multidomain vesicle coat protein that interacts with Sec23p.

Q9NP62	GCM1_HUMAN	Chorion-specific transcription factor GCMa	8962155	The gcm-motif: a novel DNA binding motif conserved in Drosophila and mammals.

O70405	ULK1_MOUSE	Serine/threonine-protein kinase ULK1	19258318	ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy.

P06105	SC160_YEAST	Protein SCP160	8533468	Scp160p, a new yeast protein associated with the nuclear membrane and the endoplasmic reticulum, is necessary for maintenance of exact ploidy.

P30355	AL5AP_MOUSE	Arachidonate 5-lipoxygenase-activating protein	19075240	The nuclear membrane organization of leukotriene synthesis.

Q9ERR1	NDEL1_MOUSE	Nuclear distribution protein nudE-like 1	11163259	A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system.

Q9Y219	JAG2_HUMAN	Protein jagged-2	9315665	Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor.

Q9VVS4	MED11_DROME	Mediator of RNA polymerase II transcription subunit 11	12021283	Novel Mediator proteins of the small Mediator complex in Drosophila SL2 cells.

Q16831	UPP1_HUMAN	Uridine phosphorylase 1	7488099	Cloning and expression of human uridine phosphorylase.

Q9GPJ1	SKEL_DROME	Protein skeletor	11134070	Skeletor, a novel chromosomal protein that redistributes during mitosis provides evidence for the formation of a spindle matrix.

P57744	TIM8_YEAST	Mitochondrial import inner membrane translocase subunit TIM8	12221072	The role of the Tim8p-Tim13p complex in a conserved import pathway for mitochondrial polytopic inner membrane proteins.

O13516	RS9A_YEAST	40S ribosomal protein S9-A	15590835	The small-subunit processome is a ribosome assembly intermediate.

Q60I27	AL2CL_HUMAN	ALS2 C-terminal-like protein	17239822	ALS2CL, a novel ALS2-interactor, modulates ALS2-mediated endosome dynamics.

Q8WTD3	ATTA_GLOMM	Attacin-A	11592981	Tsetse immune responses and trypanosome transmission: implications for the development of tsetse-based strategies to reduce trypanosomiasis.

Q9XZ58	CSN5_DROME	COP9 signalosome complex subunit 5	11779478	Drosophila JAB1/CSN5 acts in photoreceptor cells to induce glial cells.

P05050	ALKB_ECOLI	Alpha-ketoglutarate-dependent dioxygenase AlkB	12594517	Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA.

P54781	ERG5_YEAST	Cytochrome P450 61	8543054	Purification and reconstitution of activity of Saccharomyces cerevisiae P450 61, a sterol delta 22-desaturase.

P49747	COMP_HUMAN	Cartilage oligomeric matrix protein	17588949	Interaction of cartilage oligomeric matrix protein/thrombospondin 5 with aggrecan.

P36123	SA190_YEAST	SIT4-associating protein SAP190	15367655	TOR controls transcriptional and translational programs via Sap-Sit4 protein phosphatase signaling effectors.

O77203	PIAA_DICDI	Protein pianissimo A	12413895	Temperature-sensitive inhibition of development in Dictyostelium due to a point mutation in the piaA gene.

O95278	EPM2A_HUMAN	Laforin	12915448	The Lafora disease gene product laforin interacts with HIRIP5, a phylogenetically conserved protein containing a NifU-like domain.

Q96NT5	PCFT_HUMAN	Proton-coupled folate transporter	17475902	Functional characterization of human proton-coupled folate transporter/heme carrier protein 1 heterologously expressed in mammalian cells as a folate transporter.

P38257	MMS4_YEAST	Crossover junction endonuclease MMS4	11139495	Requirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiae.

P51575	P2RX1_HUMAN	P2X purinoceptor 1	8834001	Characterization and chromosomal localization of a human P2X receptor from the urinary bladder.

Q7T2H2	FGRL1_CHICK	Fibroblast growth factor receptor-like 1	12813049	Characterization of FGFRL1, a novel fibroblast growth factor (FGF) receptor preferentially expressed in skeletal tissues.

Q8N4C8	MINK1_HUMAN	Misshapen-like kinase 1	10708748	Molecular cloning of MINK, a novel member of mammalian GCK family kinases, which is up-regulated during postnatal mouse cerebral development.

P83343	PR4_PRUPE	Pathogenesis-related protein PR-4	11847241	Ethylene-responsive genes are differentially regulated during abscission, organ senescence and wounding in peach (Prunus persica).

Q9P7Y8	MID2_SCHPO	Septin ring organizing protein mid2	12668659	An anillin homologue, Mid2p, acts during fission yeast cytokinesis to organize the septin ring and promote cell separation.

P06134	ADA_ECOLI	Regulatory protein ada	1581309	Zinc binding by the methylation signaling domain of the Escherichia coli Ada protein.

P13645	K1C10_HUMAN	Keratin, type I cytoskeletal 10	1380725	Mutations in the rod domains of keratins 1 and 10 in epidermolytic hyperkeratosis.

Q12265	KPR5_YEAST	Ribose-phosphate pyrophosphokinase 5	14562095	Global analysis of protein localization in budding yeast.

P12945	NAT1_YEAST	N-terminal acetyltransferase A complex subunit NAT1	2551674	Identification and characterization of genes and mutants for an N- terminal acetyltransferase from yeast.

Q9H2K8	TAOK3_HUMAN	Serine/threonine-protein kinase TAO3	10559204	Human JIK, a novel member of the STE20 kinase family that inhibits JNK and is negatively regulated by epidermal growth factor.

Q9JHW4	SELB_MOUSE	Selenocysteine-specific elongation factor	10970870	Characterization of mSelB, a novel mammalian elongation factor for selenoprotein translation.

Q8BX65	MDFIC_MOUSE	MyoD family inhibitor domain-containing protein	17891141	Nucleolar release of Hand1 acts as a molecular switch to determine cell fate.

Q06124	PTN11_HUMAN	Tyrosine-protein phosphatase non-receptor type 11	7681589	A widely expressed human protein-tyrosine phosphatase containing src homology 2 domains.

Q9WUB6	CLCKB_MOUSE	Chloride channel protein ClC-Kb	11734858	Barttin is a Cl- channel beta-subunit crucial for renal Cl- reabsorption and inner ear K+ secretion.

Q9NRM7	LATS2_HUMAN	Serine/threonine-protein kinase LATS2	10871863	Molecular cloning of a novel human protein kinase, kpm, that is homologous to warts/lats, a Drosophila tumor suppressor.

Q9W4Z4	INSL6_DROME	Probable insulin-like peptide 6	11250149	An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control.

Q9UTJ8	RAD50_SCHPO	DNA repair protein rad50	11726502	Fission yeast Rad50 stimulates sister chromatid recombination and links cohesion with repair.

Q9SN86	MDHP_ARATH	Malate dehydrogenase, chloroplastic	9774405	A novel, non-redox-regulated NAD-dependent malate dehydrogenase from chloroplasts of Arabidopsis thaliana L.

O84876	CDUB1_CHLTR	Deubiquitinase and deneddylase Dub1	16824101	Chlamydia trachomatis-derived deubiquitinating enzymes in mammalian cells during infection.

Q96RP3	UCN2_HUMAN	Urocortin-2	11329063	Human stresscopin and stresscopin-related peptide are selective ligands for the type 2 corticotropin-releasing hormone receptor.

Q924B5	TX101_RAT	Testis-expressed protein 101	11809740	A novel lipid raft-associated glycoprotein, TEC-21, activates rat basophilic leukemia cells independently of the type 1 Fc epsilon receptor.

O95528	GTR10_HUMAN	Solute carrier family 2, facilitated glucose transporter member 10	11247674	Molecular cloning of a novel member of the GLUT family of transporters, SLC2A10 (GLUT10), localized on chromosome 20q13.1: a candidate gene for NIDDM susceptibility.

Q8GYL3	ULP1A_ARATH	Ubiquitin-like-specific protease 1A	16740136	Evolution of a signalling system that incorporates both redundancy and diversity: Arabidopsis SUMOylation.

P47076	RPC9_YEAST	DNA-directed RNA polymerase III subunit RPC9	10611227	A novel subunit of yeast RNA polymerase III interacts with the TFIIB- related domain of TFIIIB70.

O43036	RPA43_SCHPO	DNA-directed RNA polymerase I subunit rpa43	10645483	Characteristics of the cDNA of the Schizosaccharomyces pombe rpa43+ gene: structural similarity of the Rpa43 subunit of RNA-polymerase I with the Rpc25 subunit of RNA-polymerase III.

Q06975	GAR1_SCHPO	H/ACA ribonucleoprotein complex subunit 1	8502556	The SpGAR1 gene of Schizosaccharomyces pombe encodes the functional homologue of the snoRNP protein GAR1 of Saccharomyces cerevisiae.

Q13488	VPP3_HUMAN	V-type proton ATPase 116 kDa subunit a isoform 3	10329006	Genomic organization of the gene coding for TIRC7, a novel membrane protein essential for T cell activation.

Q13418	ILK_HUMAN	Integrin-linked protein kinase	19074270	The structural basis of integrin-linked kinase-PINCH interactions.

P22543	VPS34_YEAST	Phosphatidylinositol 3-kinase VPS34	8385367	Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting.

Q91ZE5	EMR4_MOUSE	EGF-like module-containing mucin-like hormone receptor-like 4	12023293	EMR4, a novel epidermal growth factor (EGF)-TM7 molecule up-regulated in activated mouse macrophages, binds to a putative cellular ligand on B lymphoma cell line A20.

P38794	PCL5_YEAST	PHO85 cyclin-5	9032248	A family of cyclin-like proteins that interact with the Pho85 cyclin- dependent kinase.

Q9ZT49	ATL45_ARATH	RING-H2 finger protein ATL45	17722694	Identification of 118 Arabidopsis transcription factor and 30 ubiquitin-ligase genes responding to chitin, a plant-defense elicitor.

O94487	PPK35_SCHPO	Serine/threonine-protein kinase ppk35	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9I8G4	ASHWN_XENLA	Ashwin	16680723	Novel gene ashwin functions in Xenopus cell survival and anteroposterior patterning.

Q08448	YO059_YEAST	Putative lipase YOR059C	10515935	Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiae.

Q9LXT3	MBF1B_ARATH	Multiprotein-bridging factor 1b	16283071	Transcriptional coactivator MBF1s from Arabidopsis predominantly localize in nucleolus.

Q8WXH0	SYNE2_HUMAN	Nesprin-2	15671068	Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscle.

P0AD49	RAIA_ECOLI	Ribosome-associated inhibitor A	15502846	Structural basis for the control of translation initiation during stress.

Q9EQL5	T4S4_RAT	Transmembrane 4 L6 family member 4	11267677	Molecular cloning of a cDNA for rat TM4SF4, a homolog of human il-TMP (TM4SF4), and enhanced expression of the corresponding gene in regenerating rat liver.

P33121	ACSL1_HUMAN	Long-chain-fatty-acid--CoA ligase 1	10548543	Identification and molecular characterization of acyl-CoA synthetase in human red cells and erythroid precursor.

O55197	C3AR_RAT	C3a anaphylatoxin chemotactic receptor	9464274	Cloning and characterization of rat C3a receptor: differential expression of rat C3a and C5a receptors by LPS stimulation.

O15239	NDUA1_HUMAN	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

Q03721	KCNC4_HUMAN	Potassium voltage-gated channel subfamily C member 4	1381835	Cloning of ShIII (Shaw-like) cDNAs encoding a novel high-voltage- activating, TEA-sensitive, type-A K+ channel.

P53200	AML1_YEAST	N(6)-adenine-specific DNA methyltransferase-like 1	14562095	Global analysis of protein localization in budding yeast.

Q9NYV9	T2R13_HUMAN	Taste receptor type 2 member 13	10761934	A novel family of mammalian taste receptors.

P32589	HSP7F_YEAST	Heat shock protein homolog SSE1	14562095	Global analysis of protein localization in budding yeast.

P38734	MUP3_YEAST	Low-affinity methionine permease	8893857	The study of methionine uptake in Saccharomyces cerevisiae reveals a new family of amino acid permeases.

Q9NS37	ZHANG_HUMAN	CREB/ATF bZIP transcription factor	10871379	Zhangfei: a second cellular protein interacts with herpes simplex virus accessory factor HCF in a manner similar to Luman and VP16.

Q9WUB4	DCTN6_MOUSE	Dynactin subunit 6	10525537	Analysis of dynactin subcomplexes reveals a novel actin-related protein associated with the Arp1 minifilament pointed end.

Q00612	G6PD1_MOUSE	Glucose-6-phosphate 1-dehydrogenase X	9330624	Somatic mutation of the glucose-6-phosphate dehydrogenase (g6pd) gene in colonic stem cells and crypt restricted loss of G6PD activity.

Q9NB04	PATJ_DROME	Patj homolog	11740560	Drosophila Stardust is a partner of Crumbs in the control of epithelial cell polarity.

O54941	SMCE1_MOUSE	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1	17640523	An essential switch in subunit composition of a chromatin remodeling complex during neural development.

P06315	KV501_HUMAN	Ig kappa chain V region EV15	3925437	Aberrant recombination events in B cell lines derived from a kappa- deficient human.

P56079	CDSA_DROME	Phosphatidate cytidylyltransferase, photoreceptor-specific	7816135	Regulation of PLC-mediated signalling in vivo by CDP-diacylglycerol synthase.

Q12395	DCN1_YEAST	Defective in cullin neddylation protein 1	15988528	The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae.

Q9UKV0	HDAC9_HUMAN	Histone deacetylase 9	11535832	Cloning and characterization of a histone deacetylase, HDAC9.

Q9BYE2	TMPSD_HUMAN	Transmembrane protease serine 13	11267681	Cloning and expression of novel mosaic serine proteases with and without a transmembrane domain from human lung.

Q6PDG5	SMRC2_MOUSE	SWI/SNF complex subunit SMARCC2	17640523	An essential switch in subunit composition of a chromatin remodeling complex during neural development.

Q9UKC9	FBXL2_HUMAN	F-box/LRR-repeat protein 2	10531035	Identification of a family of human F-box proteins.

Q91898	HESXB_XENLA	Homeobox expressed in ES cells 1-B	17511981	The homeodomain factor Xanf represses expression of genes in the presumptive rostral forebrain that specify more caudal brain regions.

Q8N2S1	LTBP4_HUMAN	Latent-transforming growth factor beta-binding protein 4	9660815	Identification and characterization of a new latent transforming growth factor-beta-binding protein, LTBP-4.

Q92186	SIA8B_HUMAN	Alpha-2,8-sialyltransferase 8B	9054414	Human STX polysialyltransferase forms the embryonic form of the neural cell adhesion molecule. Tissue-specific expression, neurite outgrowth, and chromosomal localization in comparison with another polysialyltransferase, PST.

Q9NQA5	TRPV5_HUMAN	Transient receptor potential cation channel subfamily V member 5	10945469	Molecular cloning, tissue distribution, and chromosomal mapping of the human epithelial calcium channel (ECAC1).

Q9NZI2	KCIP1_HUMAN	Kv channel-interacting protein 1	15358149	Protein-protein interactions of KChIP proteins and Kv4.2.

Q9LS09	ASF1B_ARATH	Histone chaperone ASF1B	15047893	TOUSLED kinase activity oscillates during the cell cycle and interacts with chromatin regulators.

P34227	PRX1_YEAST	Mitochondrial peroxiredoxin PRX1	10821871	Mitochondria of Saccharomyces cerevisiae contain one-conserved cysteine type peroxiredoxin with thioredoxin peroxidase activity.

Q93VR3	GME_ARATH	GDP-mannose 3,5-epimerase	11752432	Partial purification and identification of GDP-mannose 3',5'- epimerase of Arabidopsis thaliana, a key enzyme of the plant vitamin C pathway.

P53219	YG1L_YEAST	Uncharacterized abhydrolase domain-containing protein YGR031W	14562095	Global analysis of protein localization in budding yeast.

O70302	CIDEA_MOUSE	Cell death activator CIDE-A	9564035	CIDE, a novel family of cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factor.

Q8N9B5	JMY_HUMAN	Junction-mediating and -regulatory protein	19287377	p53-cofactor JMY is a multifunctional actin nucleation factor.

P42749	UBC5_ARATH	Ubiquitin-conjugating enzyme E2 5	16339806	Genome analysis and functional characterization of the E2 and RING- type E3 ligase ubiquitination enzymes of Arabidopsis.

Q9LSE2	ICE1_ARATH	Transcription factor ICE1	12672693	ICE1: a regulator of cold-induced transcriptome and freezing tolerance in Arabidopsis.

O13715	MUG5_SCHPO	Meiotically up-regulated gene 5 protein	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

Q9V3B4	BG4_DROME	Death domain-containing adapter protein BG4	10934188	dFADD, a novel death domain-containing adapter protein for the Drosophila caspase DREDD.

Q9C5K8	TIF3B_ARATH	Protein TIFY 3B	20360743	NINJA connects the co-repressor TOPLESS to jasmonate signalling.

Q24395	MTK_DROME	Metchnikowin	9736738	Differential display of peptides induced during the immune response of Drosophila: a matrix-assisted laser desorption ionization time-of- flight mass spectrometry study.

Q2WG76	RIPP2_MOUSE	Protein ripply2	17531978	Ripply2 is essential for precise somite formation during mouse early development.

Q14032	BAAT_HUMAN	Bile acid-CoA:amino acid N-acyltransferase	12239217	Conserved residues in the putative catalytic triad of human bile acid Coenzyme A:amino acid N-acyltransferase.

O00159	MYO1C_HUMAN	Myosin-Ic	9119401	Cloning of the genes encoding two murine and human cochlear unconventional type I myosins.

O95727	CRTAM_HUMAN	Cytotoxic and regulatory T-cell molecule	15811952	The tumor suppressor TSLC1/NECL-2 triggers NK-cell and CD8+ T-cell responses through the cell-surface receptor CRTAM.

Q8VEA6	CRDL2_MOUSE	Chordin-like protein 2	14660436	A novel chordin-like BMP inhibitor, CHL2, expressed preferentially in chondrocytes of developing cartilage and osteoarthritic joint cartilage.

O96008	TOM40_HUMAN	Mitochondrial import receptor subunit TOM40 homolog	12198123	Insertion and assembly of human tom7 into the preprotein translocase complex of the outer mitochondrial membrane.

Q925B3	TRPM7_RAT	Transient receptor potential cation channel subfamily M member 7	11161216	TRP-PLIK, a bifunctional protein with kinase and ion channel activities.

P53172	SDS23_YEAST	Protein SDS23	14562095	Global analysis of protein localization in budding yeast.

P31939	PUR9_HUMAN	Bifunctional purine biosynthesis protein PURH	8567683	The human purH gene product, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. Cloning, sequencing, expression, purification, kinetic analysis, and domain mapping.

O64763	ATL9_ARATH	E3 ubiquitin-protein ligase ATL9	15923325	Loss-of-function mutations in chitin responsive genes show increased susceptibility to the powdery mildew pathogen Erysiphe cichoracearum.

P0AB87	FUCA_ECOLI	L-fuculose phosphate aldolase	10821675	Catalytic action of fuculose 1-phosphate aldolase (class II) as derived from structure-directed mutagenesis.

Q9JJ26	MEFV_MOUSE	Pyrin	10818206	Isolation, genomic organization, and expression analysis of the mouse and rat homologs of MEFV, the gene for familial Mediterranean fever.

P80421	HV108_HUMAN	Ig heavy chain V-I region DOT	7737190	Characterization of the two unique human anti-flavin monoclonal immunoglobulins.

Q09488	SMA6_CAEEL	Serine/threonine-protein kinase sma-6	9847239	Specificity of TGFbeta signaling is conferred by distinct type I receptors and their associated SMAD proteins in Caenorhabditis elegans.

Q5HZK2	NRSN2_MOUSE	Neurensin-2	16527258	Molecular characterization of a transport vesicle protein Neurensin- 2, a homologue of Neurensin-1, expressed in neural cells.

P36533	RM39_YEAST	54S ribosomal protein L39, mitochondrial	2060626	Extended N-terminal sequencing of proteins of the large ribosomal subunit from yeast mitochondria.

Q8IX03	KIBRA_HUMAN	Protein KIBRA	16684779	Essential role of KIBRA in co-activator function of dynein light chain 1 in mammalian cells.

Q2M2Z5	KIZ_HUMAN	Centrosomal protein kizuna	16980960	The Plk1 target Kizuna stabilizes mitotic centrosomes to ensure spindle bipolarity.

Q05955	ADY4_YEAST	Accumulates dyads protein 4	11470404	A screen for genes required for meiosis and spore formation based on whole-genome expression.

Q05923	DUS2_HUMAN	Dual specificity protein phosphatase 2	7681221	PAC-1: a mitogen-induced nuclear protein tyrosine phosphatase.

P83244	KA132_ORTSC	Potassium channel toxin alpha-KTx 13.2	11527374	OsK2, a new selective inhibitor of Kv1.2 potassium channels purified from the venom of the scorpion Orthochirus scrobiculosus.

O36025	MPD2_SCHPO	GYF domain-containing protein mpd2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P49917	DNLI4_HUMAN	DNA ligase 4	8798671	DNA ligase IV from HeLa cell nuclei.

Q9LV58	MBF1C_ARATH	Multiprotein-bridging factor 1c	15451167	Structure and expression analysis of three subtypes of Arabidopsis MBF1 genes.

P38768	PIH1_YEAST	Protein interacting with Hsp90 1	15670595	Characterization of Saccharomyces cerevisiae Nop17p, a novel Nop58p- interacting protein that is involved in pre-rRNA processing.

Q12118	SGT2_YEAST	Small glutamine-rich tetratricopeptide repeat-containing protein 2	12482202	Small glutamine-rich protein/viral protein U-binding protein is a novel cochaperone that affects heat shock protein 70 activity.

Q9LSA6	PUB29_ARATH	U-box domain-containing protein 29	14657406	A large complement of the predicted Arabidopsis ARM repeat proteins are members of the U-box E3 ubiquitin ligase family.

Q4KMQ1	TPRN_HUMAN	Taperin	20170898	Mutations in TPRN cause a progressive form of autosomal-recessive nonsyndromic hearing loss.

Q9QY15	DDX25_MOUSE	ATP-dependent RNA helicase DDX25	15096601	Gonadotropin-regulated testicular RNA helicase (GRTH/Ddx25) is essential for spermatid development and completion of spermatogenesis.

Q92793	CBP_HUMAN	CREB-binding protein	8684459	A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A.

Q8K2X3	STN1_MOUSE	CST complex subunit STN1	19119139	A DNA polymerase-{alpha}primase cofactor with homology to replication protein A-32 regulates DNA replication in mammalian cells.

P06104	UBC2_YEAST	Ubiquitin-conjugating enzyme E2 2	9343433	The ubiquitin-conjugating enzyme Rad6 (Ubc2) is required for silencing in Saccharomyces cerevisiae.

Q9UJX6	ANC2_HUMAN	Anaphase-promoting complex subunit 2	16364912	Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C.

P38085	TAT1_YEAST	Valine/tyrosine/tryptophan amino-acid permease 1	7523855	Two FK506 resistance-conferring genes in Saccharomyces cerevisiae, TAT1 and TAT2, encode amino acid permeases mediating tyrosine and tryptophan uptake.

P07602	SAP_HUMAN	Proactivator polypeptide	2717620	Saposin A: second cerebrosidase activator protein.

O95382	M3K6_HUMAN	Mitogen-activated protein kinase kinase kinase 6	9875215	MAPKKK6, a novel mitogen-activated protein kinase kinase kinase, that associates with MAPKKK5.

Q16667	CDKN3_HUMAN	Cyclin-dependent kinase inhibitor 3	15671017	Binding of HTm4 to cyclin-dependent kinase (Cdk)-associated phosphatase (KAP).Cdk2.cyclin A complex enhances the phosphatase activity of KAP, dissociates cyclin A, and facilitates KAP dephosphorylation of Cdk2.

Q98SP8	EPABA_XENLA	Embryonic polyadenylate-binding protein A	12489691	Characterization of the poly(A) binding proteins expressed during oogenesis and early development of Xenopus laevis.

Q9M644	LEP_ARATH	Ethylene-responsive transcription factor LEP	16339853	A new role for the Arabidopsis AP2 transcription factor, LEAFY PETIOLE, in gibberellin-induced germination is revealed by the misexpression of a homologous gene, SOB2/DRN-LIKE.

Q9UKZ4	TEN1_HUMAN	Teneurin-1	10341219	Teneurin-1, a vertebrate homologue of the Drosophila pair-rule gene ten-m, is a neuronal protein with a novel type of heparin-binding domain.

Q99J23	GHDC_MOUSE	GH3 domain-containing protein	11735219	The Stat3/5 locus encodes novel endoplasmic reticulum and helicase- like proteins that are preferentially expressed in normal and neoplastic mammary tissue.

P40136	CYAA_BACAN	Calmodulin-sensitive adenylate cyclase	11807546	Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin.

Q02803	OAZ_YEAST	Ornithine decarboxylase antizyme	15538383	Polyamines regulate their synthesis by inducing expression and blocking degradation of ODC antizyme.

Q9S725	4CL2_ARATH	4-coumarate--CoA ligase 2	10417722	Three 4-coumarate:coenzyme A ligases in Arabidopsis thaliana represent two evolutionarily divergent classes in angiosperms.

Q9FY74	CMTA1_ARATH	Calmodulin-binding transcription activator 1	12218065	A calmodulin-binding/CGCG box DNA-binding protein family involved in multiple signaling pathways in plants.

O00476	NPT4_HUMAN	Sodium-dependent phosphate transport protein 4	9149941	A 1.1-Mb transcript map of the hereditary hemochromatosis locus.

Q6PAW2	UBP16_XENLA	Ubiquitin carboxyl-terminal hydrolase 16	17914355	Regulation of cell cycle progression and gene expression by H2A deubiquitination.

Q93ZN9	DAPAT_ARATH	LL-diaminopimelate aminotransferase, chloroplastic	14729919	Divergent roles in Arabidopsis thaliana development and defense of two homologous genes, aberrant growth and death2 and AGD2-LIKE DEFENSE RESPONSE PROTEIN1, encoding novel aminotransferases.

Q9FN04	AAP4_ARATH	Amino acid permease 4	7608199	Substrate specificity and expression profile of amino acid transporters (AAPs) in Arabidopsis.

Q9UBP4	DKK3_HUMAN	Dickkopf-related protein 3	10570958	Functional and structural diversity of the human Dickkopf gene family.

Q9UJU2	LEF1_HUMAN	Lymphoid enhancer-binding factor 1	12192039	I-mfa domain proteins interact with Axin and affect its regulation of the Wnt and c-Jun N-terminal kinase signaling pathways.

Q79V60	KAIC_THEEB	Circadian clock protein kinase kaiC	15256595	Structure of the C-terminal domain of the clock protein KaiA in complex with a KaiC-derived peptide: implications for KaiC regulation.

Q13459	MYO9B_HUMAN	Myosin-IXb	9490638	Human myosin-IXb is a mechanochemically active motor and a GAP for rho.

Q15797	SMAD1_HUMAN	Mothers against decapentaplegic homolog 1	17292623	Fussel-15, a novel Ski/Sno homolog protein, antagonizes BMP signaling.

Q8N8S7	ENAH_HUMAN	Protein enabled homolog	17686488	Structural basis for polyproline recognition by the FE65 WW domain.

O75012	MRP10_YEAST	37S ribosomal protein MRP10, mitochondrial	9065385	Cloning and characterization of MRP10, a yeast gene coding for a mitochondrial ribosomal protein.

Q39242	TRXB2_ARATH	Thioredoxin reductase 2	11717467	Identification and characterization of a mitochondrial thioredoxin system in plants.

Q12176	MAK21_YEAST	Ribosome biogenesis protein MAK21	9786894	Mak21p of Saccharomyces cerevisiae, a homolog of human CAATT-binding protein, is essential for 60 S ribosomal subunit biogenesis.

Q53FV1	ORML2_HUMAN	ORM1-like protein 2	20182505	Orm family proteins mediate sphingolipid homeostasis.

P57743	LSM3_YEAST	U6 snRNA-associated Sm-like protein LSm3	10369684	Sm and Sm-like proteins assemble in two related complexes of deep evolutionary origin.

O80365	ARR8_ARATH	Two-component response regulator ARR8	9607306	Stress-responsive expression of genes for two-component response regulator-like proteins in Arabidopsis thaliana.

Q15147	PLCB4_HUMAN	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4	8530101	cDNA sequence and gene locus of the human retinal phosphoinositide- specific phospholipase-C beta 4 (PLCB4).

P22061	PIMT_HUMAN	Protein-L-isoaspartate(D-aspartate) O-methyltransferase	8074695	Amino acid polymorphisms of the human L-isoaspartyl/D-aspartyl methyltransferase involved in protein repair.

Q00381	AP2S_YEAST	AP-2 complex subunit sigma	10564262	Adaptor complex-independent clathrin function in yeast.

Q9ESB5	NECA1_RAT	N-terminal EF-hand calcium-binding protein 1	12044471	NECABs: a family of neuronal Ca(2+)-binding proteins with an unusual domain structure and a restricted expression pattern.

Q8N5D6	GBGT1_HUMAN	Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1	10506200	Characterization of the human Forssman synthetase gene: an evolving association between glycolipid synthesis and host-microbial interactions.

Q92616	GCN1L_HUMAN	Translational activator GCN1	9234705	Evidence that GCN1 and GCN20, translational regulators of GCN4, function on elongating ribosomes in activation of eIF2alpha kinase GCN2.

Q9USM4	LUC7_SCHPO	U1 snRNP-associated protein usp106	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9FHX5	E1310_ARATH	Glucan endo-1,3-beta-glucosidase 10	14517339	Proteomic analysis of glycosylphosphatidylinositol-anchored membrane proteins.

Q9Y6K1	DNM3A_HUMAN	DNA (cytosine-5)-methyltransferase 3A	16357870	The Polycomb group protein EZH2 directly controls DNA methylation.

Q9NRI5	DISC1_HUMAN	Disrupted in schizophrenia 1 protein	19303846	Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling.

Q9UL16	CCD19_HUMAN	Coiled-coil domain-containing protein 19, mitochondrial	10524255	Molecular cloning of a novel tissue-specific gene from human nasopharyngeal epithelium.

Q96NY9	MUS81_HUMAN	Crossover junction endonuclease MUS81	19595721	Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair.

Q8GUK7	RMA3_ARATH	E3 ubiquitin-protein ligase RMA3	19224217	Characterization of three Arabidopsis homologs of human RING membrane anchor E3 ubiquitin ligase.

Q9Y230	RUVB2_HUMAN	RuvB-like 2	10966108	Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis.

P61088	UBE2N_HUMAN	Ubiquitin-conjugating enzyme E2 N	19340006	The ubiquitin ligase Triad1 inhibits myelopoiesis through UbcH7 and Ubc13 interacting domains.

Q03497	STE20_YEAST	Serine/threonine-protein kinase STE20	15743816	Interaction with the SH3 domain protein Bem1 regulates signaling by the Saccharomyces cerevisiae p21-activated kinase Ste20.

O60341	KDM1A_HUMAN	Lysine-specific histone demethylase 1A	20228790	Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4.

Q24157	BRN_DROME	Beta-1,3-galactosyltransferase brn	9012507	The neurogenic genes egghead and brainiac define a novel signaling pathway essential for epithelial morphogenesis during Drosophila oogenesis.

P63000	RAC1_HUMAN	Ras-related C3 botulinum toxin substrate 1	12134158	Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex.

Q15678	PTN14_HUMAN	Tyrosine-protein phosphatase non-receptor type 14	7733990	Pez: a novel human cDNA encoding protein tyrosine phosphatase- and ezrin-like domains.

P49023	PAXI_HUMAN	Paxillin	7534286	Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL.

O13967	BGS2_SCHPO	1,3-beta-glucan synthase component bgs2	10922478	Bgs2p, a 1,3-beta-glucan synthase subunit, is essential for maturation of ascospore wall in Schizosaccharomyces pombe.

P16368	TIMP2_BOVIN	Metalloproteinase inhibitor 2	9724659	Crystal structure of the complex formed by the membrane type 1-matrix metalloproteinase with the tissue inhibitor of metalloproteinases-2, the soluble progelatinase A receptor.

O60145	PPK23_SCHPO	Serine/threonine-protein kinase ppk23	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9FIJ6	ACCR4_ARATH	Serine/threonine-protein kinase-like protein CCR4	15549374	Molecular analysis of the CRINKLY4 gene family in Arabidopsis thaliana.

Q13421	MSLN_HUMAN	Mesothelin	8552591	Molecular cloning of mesothelin, a differentiation antigen present on mesothelium, mesotheliomas, and ovarian cancers.

P0A8P6	XERC_ECOLI	Tyrosine recombinase xerC	2254268	Recombination at ColE1 cer requires the Escherichia coli xerC gene product, a member of the lambda integrase family of site-specific recombinases.

P40917	YAP4_YEAST	AP-1-like transcription factor YAP4	11179441	Two nuclear proteins, Cin5 and Ydr259c, confer resistance to cisplatin in Saccharomyces cerevisiae.

O35264	PA1B2_RAT	Platelet-activating factor acetylhydrolase IB subunit beta	9459487	Molecular cloning of cDNAs encoding alpha1, alpha2, and beta subunits of rat brain platelet-activating factor acetylhydrolase.

P38142	YB91_YEAST	Probable metabolite transport protein YBR241C	14562095	Global analysis of protein localization in budding yeast.

Q9DED4	CIRBB_XENLA	Cold-inducible RNA-binding protein B	12466543	Methylation of Xenopus CIRP2 regulates its arginine- and glycine-rich region-mediated nucleocytoplasmic distribution.

Q12182	YO342_YEAST	Uncharacterized protein YOR342C	14562095	Global analysis of protein localization in budding yeast.

P83657	CAT1_COMTR	Catalase-1	12094731	Oxidative stress-induced expression of catalases in Comamonas terrigena.

P56523	CLR3_SCHPO	Histone deacetylase clr3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O94925	GLSK_HUMAN	Glutaminase kidney isoform, mitochondrial	10719215	Isolation, characterization and expression of a human brain mitochondrial glutaminase cDNA.

P53632	PAP2_YEAST	Poly(A) RNA polymerase protein 2	16373491	Contributions of Trf4p- and Trf5p-dependent polyadenylation to the processing and degradative functions of the yeast nuclear exosome.

P82270	RTD1A_MACMU	Rhesus theta defensin-1/3 subunit A	10521339	A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alpha-defensins.

P09118	URIC_RAT	Uricase	3182808	Cloning and sequence analysis of cDNA for rat liver uricase.

Q9GZV1	ANKR2_HUMAN	Ankyrin repeat domain-containing protein 2	10873377	Identification of Ankrd2, a novel skeletal muscle gene coding for a stretch-responsive ankyrin-repeat protein.

Q925G2	CYBR1_MOUSE	Cytochrome b reductase 1	11230685	An iron-regulated ferric reductase associated with the absorption of dietary iron.

Q08754	BUD7_YEAST	Bud site selection protein 7	14562095	Global analysis of protein localization in budding yeast.

Q08553	SYC1_YEAST	Protein SYC1	14562095	Global analysis of protein localization in budding yeast.

P38745	YHB7_YEAST	Uncharacterized membrane protein YHL071W	14562095	Global analysis of protein localization in budding yeast.

Q6NQ88	DDB2_ARATH	Protein DAMAGED DNA-BINDING 2	16792691	CUL4 associates with DDB1 and DET1 and its downregulation affects diverse aspects of development in Arabidopsis thaliana.

Q9FIM2	FTSH9_ARATH	ATP-dependent zinc metalloprotease FTSH 9, chloroplastic	14630971	Coordinated regulation and complex formation of yellow variegated1 and yellow variegated2, chloroplastic FtsH metalloproteases involved in the repair cycle of photosystem II in Arabidopsis thylakoid membranes.

O42874	STU1_SCHPO	Protein peg1	16951255	S. pombe CLASP needs dynein, not EB1 or CLIP170, to induce microtubule instability and slows polymerization rates at cell tips in a dynein-dependent manner.

P18171	DEC13_DROME	Defective chorion-1 protein, FC177 isoform	3378704	Cloning and analysis of the dec-1 female-sterile locus, a gene required for proper assembly of the Drosophila eggshell.

P22936	APN1_YEAST	DNA-(apurinic or apyrimidinic site) lyase 1	3056935	Yeast DNA diesterase for 3'-fragments of deoxyribose: purification and physical properties of a repair enzyme for oxidative DNA damage.

P29474	NOS3_HUMAN	Nitric oxide synthase, endothelial	11149895	NOSIP, a novel modulator of endothelial nitric oxide synthase activity.

O94500	NDUV1_SCHPO	NADH-ubiquinone oxidoreductase 51 kDa subunit, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q01705	NOTC1_MOUSE	Neurogenic locus notch homolog protein 1	15965470	DNER acts as a neuron-specific Notch ligand during Bergmann glial development.

P04921	GLPC_HUMAN	Glycophorin-C	2416746	Isolation of cDNA clones and complete amino acid sequence of human erythrocyte glycophorin C.

Q9M7T0	PRX2F_ARATH	Peroxiredoxin-2F, mitochondrial	15632145	The mitochondrial type II peroxiredoxin F is essential for redox homeostasis and root growth of Arabidopsis thaliana under stress.

Q9V6X7	OFUT1_DROME	GDP-fucose protein O-fucosyltransferase 1	11698403	Composition of Drosophila melanogaster proteome involved in fucosylated glycan metabolism.

Q7TNT2	FACR2_MOUSE	Fatty acyl-CoA reductase 2	15220348	Mammalian wax biosynthesis: I. Identification of two fatty acyl- coenzyme A reductases with different substrate specificities and tissue distributions.

Q24423	NOC_DROME	Zinc finger protein Noc	17014842	Growth control in the proliferative region of the Drosophila eye-head primordium: the elbow-noc gene complex.

O00910	STATA_DICDI	Signal transducer and activator of transcription A	9670017	Developmentally and spatially regulated activation of a Dictyostelium STAT protein by a serpentine receptor.

Q99426	TBCB_HUMAN	Tubulin-folding cofactor B	16303566	Gigaxonin interacts with tubulin folding cofactor B and controls its degradation through the ubiquitin-proteasome pathway.

Q12923	PTN13_HUMAN	Tyrosine-protein phosphatase non-receptor type 13	7536343	FAP-1: a protein tyrosine phosphatase that associates with Fas.

Q15283	RASA2_HUMAN	Ras GTPase-activating protein 2	8812506	cDNA cloning and chromosomal mapping of a novel human GAP (GAP1M), a GTPase-activating protein of Ras.

P84684	SC41_TITCA	Toxin Tc41	15025998	Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

P31673	HS174_ORYSJ	17.4 kDa class I heat shock protein	15803416	Characterization of the genomic structures and selective expression profiles of nine class I small heat shock protein genes clustered on two chromosomes in rice (Oryza sativa L.).

P07936	NEUM_RAT	Neuromodulin	2437653	Cloning of complementary DNA for GAP-43, a neuronal growth-related protein.

Q9CQ45	NENF_MOUSE	Neudesin	15605373	Neudesin, a novel secreted protein with a unique primary structure and neurotrophic activity.

P36776	LONM_HUMAN	Lon protease homolog, mitochondrial	17420247	Roles for the human ATP-dependent Lon protease in mitochondrial DNA maintenance.

P38629	RFC3_YEAST	Replication factor C subunit 3	10660302	A novel Rad24 checkpoint protein complex closely related to replication factor C.

P14373	TRI27_HUMAN	Zinc finger protein RFP	10504338	Interaction between the Ret finger protein and the Int-6 gene product and co-localisation into nuclear bodies.

Q8GYD2	MND1_ARATH	Meiotic nuclear division protein 1 homolog	19187040	A novel ATM dependant X-ray inducible gene is essential for both plant meiosis and gametogenesis.

Q9NS18	GLRX2_HUMAN	Glutaredoxin-2, mitochondrial	11297543	Cloning and expression of a novel human glutaredoxin (Grx2) with mitochondrial and nuclear isoforms.

Q15036	SNX17_HUMAN	Sorting nexin-17	11237770	A new member of the sorting nexin family interacts with the C- terminus of P-selectin.

Q9P1T7	MDFIC_HUMAN	MyoD family inhibitor domain-containing protein	10671520	Molecular cloning of a novel human I-mfa domain-containing protein that differently regulates human T-cell leukemia virus type I and HIV- 1 expression.

Q8LAW2	AFR_ARATH	F-box protein AFR	14653999	The F box protein AFR is a positive regulator of phytochrome A- mediated light signaling.

P21926	CD9_HUMAN	CD9 antigen	7511626	CD9-regulated adhesion. Anti-CD9 monoclonal antibody induce pre-B cell adhesion to bone marrow fibroblasts through de novo recognition of fibronectin.

Q9SB04	ARR5_ARATH	Two-component response regulator ARR5	9634588	Two genes with similarity to bacterial response regulators are rapidly and specifically induced by cytokinin in Arabidopsis.

P17542	TAL1_HUMAN	T-cell acute lymphocytic leukemia protein 1	2303035	The tal gene undergoes chromosome translocation in T cell leukemia and potentially encodes a helix-loop-helix protein.

P70040	FEN1A_XENLA	Flap endonuclease 1-A	9852084	Characterization of FEN-1 from Xenopus laevis. cDNA cloning and role in DNA metabolism.

P63208	SKP1_HUMAN	S-phase kinase-associated protein 1	16880511	Regulation of p27 degradation and S-phase progression by Ro52 RING finger protein.

Q7KZI7	MARK2_HUMAN	Serine/threonine-protein kinase MARK2	8274451	Identification of 21 novel human protein kinases, including 3 members of a family related to the cell cycle regulator nimA of Aspergillus nidulans.

P27895	CIN8_YEAST	Kinesin-like protein CIN8	1618897	Two Saccharomyces cerevisiae kinesin-related gene products required for mitotic spindle assembly.

P55263	ADK_HUMAN	Adenosine kinase	9070863	Cloning and expression of the adenosine kinase gene from rat and human tissues.

Q38954	PHT21_ARATH	Inorganic phosphate transporter 2-1, chloroplastic	12938931	Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis.

Q9YHV3	NOGG3_DANRE	Noggin-3	9882485	Follistatin and noggin are excluded from the zebrafish organizer.

P36612	PRS4_SCHPO	26S protease regulatory subunit 4 homolog	8247131	Defective mitosis due to a mutation in the gene for a fission yeast 26S protease subunit.

Q13424	SNTA1_HUMAN	Alpha-1-syntrophin	10212242	Stress-activated protein kinase-3 interacts with the PDZ domain of alpha1-syntrophin. A mechanism for specific substrate recognition.

P36604	GRP78_SCHPO	78 kDa glucose-regulated protein homolog	1373379	Analysis of the BiP gene and identification of an ER retention signal in Schizosaccharomyces pombe.

Q8IN23	GR93B_DROME	Putative gustatory receptor 93b	10710312	Candidate taste receptors in Drosophila.

O14965	STK6_HUMAN	Serine/threonine-protein kinase 6	18615013	Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery.

P06748	NPM_HUMAN	Nucleophosmin	18809582	Nucleophosmin serves as a rate-limiting nuclear export chaperone for the Mammalian ribosome.

P30731	GPR83_MOUSE	Probable G-protein coupled receptor 83	1663214	Identification of a gene induced by glucocorticoids in murine T- cells: a potential G protein-coupled receptor.

Q9UT11	YLW3_SCHPO	Uncharacterized zinc transporter P8A3.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O80845	PX11D_ARATH	Peroxisomal membrane protein 11D	17220199	The PEROXIN11 protein family controls peroxisome proliferation in Arabidopsis.

Q9I7U4	TITIN_DROME	Titin	9917396	Association of kettin with actin in the Z-disc of insect flight muscle.

Q16667	CDKN3_HUMAN	Cyclin-dependent kinase inhibitor 3	11463386	Phosphoprotein-protein interactions revealed by the crystal structure of kinase-associated phosphatase in complex with phosphoCDK2.

B2GV87	PTPRE_RAT	Receptor-type tyrosine-protein phosphatase epsilon	15738637	Receptor-type protein tyrosine phosphatase epsilon (PTPepsilonM) is a negative regulator of insulin signaling in primary hepatocytes and liver.

O00429	DNM1L_HUMAN	Dynamin-1-like protein	9786947	A human dynamin-related protein controls the distribution of mitochondria.

Q08378	GOGA3_HUMAN	Golgin subfamily A member 3	9295333	Molecular characterization of GCP170, a 170-kDa protein associated with the cytoplasmic face of the Golgi membrane.

Q6IFU8	K1C17_RAT	Keratin, type I cytoskeletal 17	15085952	Comprehensive analysis of keratin gene clusters in humans and rodents.

Q02224	CENPE_HUMAN	Centromere-associated protein E	1406971	CENP-E is a putative kinetochore motor that accumulates just before mitosis.

P38620	KPR2_YEAST	Ribose-phosphate pyrophosphokinase 2	14562095	Global analysis of protein localization in budding yeast.

Q9UGP4	LIMD1_HUMAN	LIM domain-containing protein 1	15542589	LIM domains-containing protein 1 (LIMD1), a tumor suppressor encoded at chromosome 3p21.3, binds pRB and represses E2F-driven transcription.

P63279	UBC9_HUMAN	SUMO-conjugating enzyme UBC9	17956732	RSUME, a small RWD-containing protein, enhances SUMO conjugation and stabilizes HIF-1alpha during hypoxia.

Q06616	YP174_YEAST	Nuclear envelope protein YPR174C	15282802	Localization of proteins that are coordinately expressed with Cln2 during the cell cycle.

Q09840	AMY2_SCHPO	Alpha-amylase 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8NFZ4	NLGN2_HUMAN	Neuroligin-2	10892652	Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons.

Q13823	NOG2_HUMAN	Nucleolar GTP-binding protein 2	8822211	Cloning of a novel nucleolar guanosine 5'-triphosphate binding protein autoantigen from a breast tumor.

Q6WV20	GALT1_DROME	Polypeptide N-acetylgalactosaminyltransferase 1	12829714	Functional characterization and expression analysis of members of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family from Drosophila melanogaster.

Q9ERR1	NDEL1_MOUSE	Nuclear distribution protein nudE-like 1	16203747	Recruitment of katanin p60 by phosphorylated NDEL1, an LIS1 interacting protein, is essential for mitotic cell division and neuronal migration.

Q39242	TRXB2_ARATH	Thioredoxin reductase 2	15642341	AtNTRB is the major mitochondrial thioredoxin reductase in Arabidopsis thaliana.

Q6X5Y6	WRI1_ARATH	Ethylene-responsive transcription factor WRI1	9733529	wrinkled1: A novel, low-seed-oil mutant of Arabidopsis with a deficiency in the seed-specific regulation of carbohydrate metabolism.

Q5VZM2	RRAGB_HUMAN	Ras-related GTP-binding protein B	11073942	Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B.

P62714	PP2AB_HUMAN	Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	8206937	The catalytic subunit of protein phosphatase 2A is carboxyl- methylated in vivo.

Q61026	NCOA2_MOUSE	Nuclear receptor coactivator 2	10381882	Regulation of transcription by a protein methyltransferase.

Q03178	PIR1_YEAST	Cell wall mannoprotein PIR1	10407261	Role of NaOH-extractable cell wall proteins Ccw5p, Ccw6p, Ccw7p and Ccw8p (members of the Pir protein family) in stability of the Saccharomyces cerevisiae cell wall.

P27487	DPP4_HUMAN	Dipeptidyl peptidase 4	15448155	One site mutation disrupts dimer formation in human DPP-IV proteins.

Q642G4	PEX14_RAT	Peroxisomal membrane protein PEX14	10212238	The peroxin Pex14p. cDNA cloning by functional complementation on a Chinese hamster ovary cell mutant, characterization, and functional analysis.

Q9H2X3	CLC4M_HUMAN	C-type lectin domain family 4 member M	11257134	A dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN)-related protein is highly expressed on human liver sinusoidal endothelial cells and promotes HIV-1 infection.

P22985	XDH_RAT	Xanthine dehydrogenase/oxidase	2387845	Proteolytic conversion of xanthine dehydrogenase from the NAD- dependent type to the O2-dependent type. Amino acid sequence of rat liver xanthine dehydrogenase and identification of the cleavage sites of the enzyme protein during irreversible conversion by trypsin.

Q9EPQ8	TCF20_MOUSE	Transcription factor 20	10849425	Interaction between the transcription factor SPBP and the positive cofactor RNF4. An interplay between protein binding zinc fingers.

Q13586	STIM1_HUMAN	Stromal interaction molecule 1	11463338	Identification and characterization of the STIM (stromal interaction molecule) gene family: coding for a novel class of transmembrane proteins.

Q9C826	ABA2_ARATH	Xanthoxin dehydrogenase	12417697	A unique short-chain dehydrogenase/reductase in Arabidopsis glucose signaling and abscisic acid biosynthesis and functions.

P61458	PHS_MOUSE	Pterin-4-alpha-carbinolamine dehydratase	1763325	Characterization of a cofactor that regulates dimerization of a mammalian homeodomain protein.

Q93033	IGSF2_HUMAN	Immunoglobulin superfamily member 2	7722300	V7, a novel leukocyte surface protein that participates in T cell activation. II. Molecular cloning and characterization of the V7 gene.

P60390	RSMH_ECOLI	Ribosomal RNA small subunit methyltransferase H	10572301	mraW, an essential gene at the dcw cluster of Escherichia coli codes for a cytoplasmic protein with methyltransferase activity.

P33400	PACC_YEAST	pH-response transcription factor pacC/RIM101	12509465	The transcription factor Rim101p governs ion tolerance and cell differentiation by direct repression of the regulatory genes NRG1 and SMP1 in Saccharomyces cerevisiae.

P32561	RPD3_YEAST	Histone deacetylase RPD3	16314178	Stable incorporation of sequence specific repressors Ash1 and Ume6 into the Rpd3L complex.

P46777	RL5_HUMAN	60S ribosomal protein L5	7772601	Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs.

Q9P109	GCNT4_HUMAN	Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4	10753916	Control of O-glycan branch formation. Molecular cloning and characterization of a novel thymus-associated core 2 beta1, 6-n- acetylglucosaminyltransferase.

Q9LXE5	DRM1_ARATH	DNA (cytosine-5)-methyltransferase DRM1	12121623	Role of the arabidopsis DRM methyltransferases in de novo DNA methylation and gene silencing.

P50289	ASPX_MOUSE	Acrosomal protein SP-10	1591350	Molecular and developmental studies of a sperm acrosome antigen recognized by HS-63 monoclonal antibody.

P20385	CF2_DROME	Chorion transcription factor Cf2	1411512	Multiple zinc finger forms resulting from developmentally regulated alternative splicing of a transcription factor gene.

Q9Y5Z0	BACE2_HUMAN	Beta-secretase 2	10749877	Expression analysis of BACE2 in brain and peripheral tissues.

Q59WG7	BIG1_CANAL	Protein BIG1	16552067	Deletion of the CaBIG1 gene reduces beta-1,6-glucan synthesis, filamentation, adhesion, and virulence in Candida albicans.

O15234	CASC3_HUMAN	Protein CASC3	12080473	Metastatic lymph node 51, a novel nucleo-cytoplasmic protein overexpressed in breast cancer.

P24347	MMP11_HUMAN	Stromelysin-3	1701851	A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas.

P23566	UBC2_SCHPO	Ubiquitin-conjugating enzyme E2 2	12417737	Two ubiquitin-conjugating enzymes, Rhp6 and UbcX, regulate heterochromatin silencing in Schizosaccharomyces pombe.

Q9C0W0	MIS15_SCHPO	Kinetochore protein mis15	15369671	Mis16 and Mis18 are required for CENP-A loading and histone deacetylation at centromeres.

Q9C5Y0	PLDD1_ARATH	Phospholipase D delta	11489173	Involvement of a novel Arabidopsis phospholipase D, AtPLDdelta, in dehydration-inducible accumulation of phosphatidic acid in stress signalling.

Q708W2	FXJ1A_XENLA	Forkhead box protein J1-A	15656969	Of fox and frogs: fox (fork head/winged helix) transcription factors in Xenopus development.

P47868	SCG3_RAT	Secretogranin-3	7917832	Primary structure of mouse secretogranin III and its absence from deficient mice.

Q9UT92	YL47_SCHPO	Uncharacterized transporter C323.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q60813	ADM1A_MOUSE	Disintegrin and metalloproteinase domain-containing protein 1a	12095680	The ADAM1a and ADAM1b genes, instead of the ADAM1 (fertilin alpha) gene, are localized on mouse chromosome 5.

O88448	KLC2_MOUSE	Kinesin light chain 2	9624122	Two kinesin light chain genes in mice. Identification and characterization of the encoded proteins.

P06525	ADH1_ARATH	Alcohol dehydrogenase class-P	2277648	Sequence analysis of two null-mutant alleles of the single Arabidopsis Adh locus.

O74518	CID12_SCHPO	Poly(A) RNA polymerase cid12	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O80860	FTSH2_ARATH	ATP-dependent zinc metalloprotease FTSH 2, chloroplastic	14630971	Coordinated regulation and complex formation of yellow variegated1 and yellow variegated2, chloroplastic FtsH metalloproteases involved in the repair cycle of photosystem II in Arabidopsis thylakoid membranes.

Q8N0X7	SPG20_HUMAN	Spartin	19580544	Endogenous spartin (SPG20) is recruited to endosomes and lipid droplets and interacts with the ubiquitin E3 ligases AIP4 and AIP5.

P67811	SC11A_CANFA	Signal peptidase complex catalytic subunit SEC11A	3511473	Purification of microsomal signal peptidase as a complex.

Q9H0H0	INT2_HUMAN	Integrator complex subunit 2	16239144	Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.

P84783	CABM1_MACCH	Carbamoylase-1	15501292	Purification and characterization of paralytic shellfish toxin transforming enzyme from Mactra chinensis.

Q6QHC5	DEGS2_HUMAN	Sphingolipid delta(4)-desaturase/C4-hydroxylase DES2	15063729	Identification of the human sphingolipid C4-hydroxylase, hDES2, and its up-regulation during keratinocyte differentiation.

Q16572	VACHT_HUMAN	Vesicular acetylcholine transporter	8071310	Functional identification of a vesicular acetylcholine transporter and its expression from a 'cholinergic' gene locus.

O15116	LSM1_HUMAN	U6 snRNA-associated Sm-like protein LSm1	18172165	Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'.

P29590	PML_HUMAN	Probable transcription factor PML	11331580	The tripartite motif family identifies cell compartments.

O74956	RT08_SCHPO	37S ribosomal protein subunit S8, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q96EZ8	MCRS1_HUMAN	Microspherule protein 1	17014843	DIPA, which can localize to the centrosome, associates with p78/MCRS1/MSP58 and acts as a repressor of gene transcription.

Q21502	MEP1_CAEEL	MOG interacting and ectopic P-granules protein 1	12808046	Caenorhabditis elegans UNC-98, a C2H2 Zn finger protein, is a novel partner of UNC-97/PINCH in muscle adhesion complexes.

P34609	JIP_CAEEL	JNK-interacting protein	10393177	A Caenorhabditis elegans JNK signal transduction pathway regulates coordinated movement via type-D GABAergic motor neurons.

Q9FHW7	SKP1B_ARATH	SKP1-like protein 1B	15310821	Identification of ASK and clock-associated proteins as molecular partners of LKP2 (LOV kelch protein 2) in Arabidopsis.

P35583	FOXA2_MOUSE	Hepatocyte nuclear factor 3-beta	17596284	Foxa1 and Foxa2 regulate multiple phases of midbrain dopaminergic neuron development in a dosage-dependent manner.

P78871	RST2_SCHPO	Zinc finger protein rst2	10982411	A zinc-finger protein, Rst2p, regulates transcription of the fission yeast ste11(+) gene, which encodes a pivotal transcription factor for sexual development.

Q9Y810	SHY1_SCHPO	Cytochrome oxidase assembly protein shy1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q7Z6M1	RABEK_HUMAN	Rab9 effector protein with kelch motifs	9230071	A novel Rab9 effector required for endosome-to-TGN transport.

Q9NP71	WBS14_HUMAN	Williams-Beuren syndrome chromosomal region 14 protein	10780788	WBSCR14, a putative transcription factor gene deleted in Williams- Beuren syndrome: complete characterisation of the human gene and the mouse ortholog.

Q9NYR9	KBRS2_HUMAN	NF-kappa-B inhibitor-interacting Ras-like protein 2	10657303	A subclass of Ras proteins that regulate the degradation of IkappaB.

P01215	GLHA_HUMAN	Glycoprotein hormones alpha chain	481597	Isolation, cloning and sequence analysis of the cDNA for the alpha- subunit of human chorionic gonadotropin.

P97690	SMC3_RAT	Structural maintenance of chromosomes protein 3	9015313	cDNA cloning of the basement membrane chondroitin sulfate proteoglycan core protein, bamacan: a five domain structure including coiled-coil motifs.

Q99626	CDX2_HUMAN	Homeobox protein CDX-2	9459001	Cloning and chromosome assignment of the human CDX2 gene.

P50443	S26A2_HUMAN	Sulfate transporter	8528239	Achondrogenesis type IB is caused by mutations in the diastrophic dysplasia sulphate transporter gene.

Q940H6	SRK2E_ARATH	Serine/threonine-protein kinase SRK2E	16365038	The regulatory domain of SRK2E/OST1/SnRK2.6 interacts with ABI1 and integrates abscisic acid (ABA) and osmotic stress signals controlling stomatal closure in Arabidopsis.

Q86H98	CHMP4_DICDI	Charged multivesicular body protein 4	15708561	Dd-Alix, a conserved endosome-associated protein, controls Dictyostelium development.

P35638	DDIT3_HUMAN	DNA damage-inducible transcript 3 protein	7503811	Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma.

Q1MTQ0	BRL1_SCHPO	E3 ubiquitin-protein ligase brl1	17374714	Ubiquitylation of histone H2B controls RNA polymerase II transcription elongation independently of histone H3 methylation.

Q9R0L6	PCM1_MOUSE	Pericentriolar material 1 protein	12571289	Non-membranous granular organelle consisting of PCM-1: subcellular distribution and cell-cycle-dependent assembly/disassembly.

P36507	MP2K2_HUMAN	Dual specificity mitogen-activated protein kinase kinase 2	8388392	Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2.

P33895	NUF2_YEAST	Kinetochore protein NUF2	11266451	The Ndc80p complex from Saccharomyces cerevisiae contains conserved centromere components and has a function in chromosome segregation.

Q27395	LI15B_CAEEL	Protein lin-15B	7982579	The Caenorhabditis elegans locus lin-15, a negative regulator of a tyrosine kinase signaling pathway, encodes two different proteins.

Q8SX83	SPEN_DROME	Protein split ends	12783785	Splits ends is a tissue/promoter specific regulator of Wingless signaling.

Q9Z2F5	CTBP1_RAT	C-terminal-binding protein 1	16940172	Specific recognition of ZNF217 and other zinc finger proteins at a surface groove of C-terminal binding proteins.

Q9PTK2	FOXE4_XENLA	Forkhead box protein E4	15656969	Of fox and frogs: fox (fork head/winged helix) transcription factors in Xenopus development.

Q920M9	SIAH1_RAT	E3 ubiquitin-protein ligase SIAH1	11786535	Regulation of synaptophysin degradation by mammalian homologues of Seven in Absentia.

P07632	SODC_RAT	Superoxide dismutase [Cu-Zn]	2703531	Rat lung Cu,Zn superoxide dismutase. Isolation and sequence of a full-length cDNA and studies of enzyme induction.

P50399	GDIB_RAT	Rab GDP dissociation inhibitor beta	8188702	Molecular cloning and characterization of two rab GDI species from rat brain: brain-specific and ubiquitous types.

O74503	UAF30_SCHPO	Upstream activation factor subunit spp27	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P84077	ARF1_HUMAN	ADP-ribosylation factor 1	1577740	Characterization of the human gene encoding ADP-ribosylation factor 1, a guanine nucleotide-binding activator of cholera toxin.

P0AGD1	SODC_ECOLI	Superoxide dismutase [Cu-Zn]	8626323	Cloning and analysis of sodC, encoding the copper-zinc superoxide dismutase of Escherichia coli.

P20132	SDHL_HUMAN	L-serine dehydratase/L-threonine deaminase	18342636	A catalytic mechanism that explains a low catalytic activity of serine dehydratase like-1 from human cancer cells: crystal structure and site-directed mutagenesis studies.

P08708	RS17_HUMAN	40S ribosomal protein S17	17647292	Ribosomal protein S17 gene (RPS17) is mutated in Diamond-Blackfan anemia.

O95347	SMC2_HUMAN	Structural maintenance of chromosomes protein 2	11136719	Chromosome condensation by a human condensin complex in Xenopus egg extracts.

P48449	ERG7_HUMAN	Lanosterol synthase	7639730	Molecular cloning of the human gene encoding lanosterol synthase from a liver cDNA library.

Q9V7W1	PIGV_DROME	GPI mannosyltransferase 2	11102367	Mutations affecting the development of the peripheral nervous system in Drosophila: a molecular screen for novel proteins.

Q09822	CDC15_SCHPO	Cell division control protein 15	7634333	The S. pombe cdc15 gene is a key element in the reorganization of F- actin at mitosis.

O95273	CCDB1_HUMAN	Cyclin-D1-binding protein 1	15887118	Human homologue of maid is a useful marker protein in hepatocarcinogenesis.

Q60739	BAG1_MOUSE	BAG family molecular chaperone regulator 1	9396724	Mammalian cells express two differently localized Bag-1 isoforms generated by alternative translation initiation.

Q9P0J0	NDUAD_HUMAN	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

Q13362	2A5G_HUMAN	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform	8703017	The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm.

Q9V6Q2	CID_DROME	Histone H3-like centromeric protein cid	10639145	Heterochromatic deposition of centromeric histone H3-like proteins.

Q07895	YL001_YEAST	FAS1 domain-containing protein YLR001C	14562095	Global analysis of protein localization in budding yeast.

P02729	GLUR_HUMAN	Urine glycopeptide	5126885	Identification in urine of a low-molecular-weight highly polar glycopeptide containing cysteinyl-galactose.

Q39026	MPK6_ARATH	Mitogen-activated protein kinase 6	10717008	Functional analysis of oxidative stress-activated mitogen-activated protein kinase cascade in plants.

O55057	PDE6D_MOUSE	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	9781033	Cloning and gene structure of the rod cGMP phosphodiesterase delta subunit gene (PDED) in man and mouse.

Q54R41	GPA9_DICDI	Guanine nucleotide-binding protein alpha-9 subunit	15059962	A G alpha-dependent pathway that antagonizes multiple chemoattractant responses that regulate directional cell movement.

Q06512	NOC4_YEAST	Nucleolar complex protein 4	15590835	The small-subunit processome is a ribosome assembly intermediate.

Q06511	RRP15_YEAST	Ribosomal RNA-processing protein 15	14562095	Global analysis of protein localization in budding yeast.

Q9H0H5	RGAP1_HUMAN	Rac GTPase-activating protein 1	18511905	Sequential Cyk-4 binding to ECT2 and FIP3 regulates cleavage furrow ingression and abscission during cytokinesis.

Q9C1X0	YN55_SCHPO	Uncharacterized WD repeat-containing protein C713.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O13927	THT2_SCHPO	Twin horsetail protein 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9SL02	RAD50_ARATH	DNA repair protein RAD50	11306548	Homologous recombination in planta is stimulated in the absence of Rad50.

O16850	FOXO_CAEEL	Forkhead box protein O	18358814	Direct inhibition of the longevity-promoting factor SKN-1 by insulin- like signaling in C. elegans.

O60603	TLR2_HUMAN	Toll-like receptor 2	17889651	Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide.

P36097	TTI1_YEAST	TEL2-interacting protein 1	19040720	Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment.

P84022	SMAD3_HUMAN	Mothers against decapentaplegic homolog 3	15897867	Oligomerization of Evi-1 regulated by the PR domain contributes to recruitment of corepressor CtBP.

Q09796	KA111_SCHPO	Importin beta-like protein kap111	15116432	Identification of genes encoding putative nucleoporins and transport factors in the fission yeast Schizosaccharomyces pombe: a deletion analysis.

P15848	ARSB_HUMAN	Arylsulfatase B	2303452	Phylogenetic conservation of arylsulfatases. cDNA cloning and expression of human arylsulfatase B.

P25774	CATS_HUMAN	Cathepsin S	8157683	Human cathepsin S: chromosomal localization, gene structure, and tissue distribution.

Q03164	MLL1_HUMAN	Histone-lysine N-methyltransferase MLL	19556245	On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex.

Q9NYS0	KBRS1_HUMAN	NF-kappa-B inhibitor-interacting Ras-like protein 1	10657303	A subclass of Ras proteins that regulate the degradation of IkappaB.

Q86VQ6	TRXR3_HUMAN	Thioredoxin reductase 3	10455115	Redox regulation of cell signaling by selenocysteine in mammalian thioredoxin reductases.

P07834	CDC4_YEAST	Cell division control protein 4	11500370	Cic1, an adaptor protein specifically linking the 26S proteasome to its substrate, the SCF component Cdc4.

P62329	TYB4_RAT	Thymosin beta-4	2325669	Thymosin beta 4 is expressed in ROS 17/2.8 osteosarcoma cells in a regulated manner.

Q61271	ACV1B_MOUSE	Activin receptor type-1B	7577669	Expression of type I and type IB receptors for activin in midgestation mouse embryos suggests distinct functions in organogensis.

Q23529	HOOK_CAEEL	Zygote defective protein 12	14697201	The C. elegans hook protein, ZYG-12, mediates the essential attachment between the centrosome and nucleus.

P31388	5HT6R_RAT	5-hydroxytryptamine receptor 6	7680751	Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs.

P97480	EYA3_MOUSE	Eyes absent homolog 3	14628052	Eyes absent represents a class of protein tyrosine phosphatases.

Q24760	FRIZ_DROVI	Frizzled	8770598	Molecular analysis of EMS-induced frizzled mutations in Drosophila melanogaster.

Q9BXR5	TLR10_HUMAN	Toll-like receptor 10	11267672	Identification of hTLR10: a novel human Toll-like receptor preferentially expressed in immune cells.

P39968	VAC8_YEAST	Vacuolar protein 8	10837477	Apg13p and Vac8p are part of a complex of phosphoproteins that are required for cytoplasm to vacuole targeting.

P16467	PDC5_YEAST	Pyruvate decarboxylase isozyme 2	12499363	The catabolism of amino acids to long chain and complex alcohols in Saccharomyces cerevisiae.

Q96E93	KLRG1_HUMAN	Killer cell lectin-like receptor subfamily G member 1	9765598	Human MAFA has alternatively spliced variants.

P32347	DCUP_YEAST	Uroporphyrinogen decarboxylase	1471989	Identification of amino acid changes affecting yeast uroporphyrinogen decarboxylase activity by sequence analysis of hem12 mutant alleles.

P07171	CALB1_RAT	Calbindin	2792772	Cloning and analysis of calbindin-D28K cDNA and its expression in the central nervous system.

O88618	FTCD_RAT	Formimidoyltransferase-cyclodeaminase	12160147	A novel type of regulation of the vimentin intermediate filament cytoskeleton by a Golgi protein.

O46227	A33A_DROME	Accessory gland peptide Acp33A	9474779	New genes for male accessory gland proteins in Drosophila melanogaster.

Q12117	MRH1_YEAST	Protein MRH1	10675524	Expression and subcellular localization of a membrane protein related to Hsp30p in Saccharomyces cerevisiae.

Q7Z7L7	ZER1_HUMAN	Protein zer-1 homolog	17304241	The Caenorhabditis elegans cell-cycle regulator ZYG-11 defines a conserved family of CUL-2 complex components.

Q96PE3	INP4A_HUMAN	Type I inositol-3,4-bisphosphate 4-phosphatase	7608176	The isolation and characterization of cDNA encoding human and rat brain inositol polyphosphate 4-phosphatase.

Q9BPW9	DHRS9_HUMAN	Dehydrogenase/reductase SDR family member 9	11304534	Characterization of a novel airway epithelial cell-specific short chain alcohol dehydrogenase/reductase gene whose expression is up- regulated by retinoids and is involved in the metabolism of retinol.

Q9Z261	CLD7_MOUSE	Claudin-7	10601346	Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins.

P41888	TNR3_SCHPO	Thiamine pyrophosphokinase	7499352	Schizosaccharomyces pombe thiamine pyrophosphokinase is encoded by gene tnr3 and is a regulator of thiamine metabolism, phosphate metabolism, mating, and growth.

Q8T626	DLT_DROME	Protein disks lost	12454076	Vanaso is a candidate quantitative trait gene for Drosophila olfactory behavior.

P76245	YEAP_ECOLI	Probable diguanylate cyclase YeaP	15716451	Cyclic diguanylate is a ubiquitous signaling molecule in bacteria: insights into biochemistry of the GGDEF protein domain.

P40548	SNL1_YEAST	HSP70 co-chaperone SNL1	9450961	The integral membrane protein snl1p is genetically linked to yeast nuclear pore complex function.

O15525	MAFG_HUMAN	Transcription factor MafG	9286713	Molecular characterization and localization of the human MAFG gene.

Q02086	SP2_HUMAN	Transcription factor Sp2	1341900	Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expression.

Q9Y0I1	EAF3_DROME	NuA4 complex subunit EAF3 homolog	15528408	Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions.

Q6NLQ8	XB32_ARATH	E3 ubiquitin-protein ligase XBAT32	15584963	The ubiquitin ligase XBAT32 regulates lateral root development in Arabidopsis.

P58821	CALY_RAT	Neuron-specific vesicular protein calcyon	11920718	Calcyon in the rat brain: cloning of cDNA and expression of mRNA.

P02778	CXL10_HUMAN	C-X-C motif chemokine 10	3925348	Gamma-interferon transcriptionally regulates an early-response gene containing homology to platelet proteins.

P97521	MCAT_RAT	Mitochondrial carnitine/acylcarnitine carrier protein	9032458	The mitochondrial carnitine carrier protein: cDNA cloning, primary structure and comparison with other mitochondrial transport proteins.

Q9P359	PGLR2_ASPAW	Endopolygalacturonase II	10993142	Cloning and heterologous expression of gene encoding A polygalacturonase from Aspergillus awamori.

Q9QX60	DGUOK_MOUSE	Deoxyguanosine kinase, mitochondrial	10455141	Cloning and characterization of mouse deoxyguanosine kinase. Evidence for a cytoplasmic isoform.

Q9FT69	RQSIM_ARATH	ATP-dependent DNA helicase Q-like SIM	16371241	The RecQ gene family in plants.

Q10198	NDC80_SCHPO	Kinetochore protein ndc80	15728720	Dissociation of the Nuf2-Ndc80 complex releases centromeres from the spindle-pole body during meiotic prophase in fission yeast.

P49711	CTCF_HUMAN	Transcriptional repressor CTCF	16107875	CTCF binding and higher order chromatin structure of the H19 locus are maintained in mitotic chromatin.

Q6EV70	OFUT1_RAT	GDP-fucose protein O-fucosyltransferase 1	15653671	O-fucosylation of notch occurs in the endoplasmic reticulum.

Q14320	FA50A_HUMAN	Protein FAM50A	9339379	Differential expression of XAP5, a candidate disease gene.

Q680Q4	SIZ1_ARATH	E3 SUMO-protein ligase SIZ1	15894620	The Arabidopsis SUMO E3 ligase SIZ1 controls phosphate deficiency responses.

Q12172	YRR1_YEAST	Zinc finger transcription factor YRR1	11909958	New insights into the pleiotropic drug resistance network from genome-wide characterization of the YRR1 transcription factor regulation system.

P84642	CIRD_CHAPA	Circulin-D	10691702	New circulin macrocyclic polypeptides from Chassalia parvifolia.

Q01852	TIM44_YEAST	Mitochondrial import inner membrane translocase subunit TIM44	1396562	MPI1, an essential gene encoding a mitochondrial membrane protein, is possibly involved in protein import into yeast mitochondria.

P15242	TEST2_RAT	Testin-2	7711203	Rat testin is a newly identified component of the junctional complexes in various tissues whose mRNA is predominantly expressed in the testis and ovary.

Q9Y696	CLIC4_HUMAN	Chloride intracellular channel protein 4	14569596	CLIC4 is enriched at cell-cell junctions and colocalizes with AKAP350 at the centrosome and midbody of cultured mammalian cells.

O43826	G6PT1_HUMAN	Glucose-6-phosphate translocase	9428641	Sequence of a putative glucose 6-phosphate translocase, mutated in glycogen storage disease type Ib.

O42666	BUT1_SCHPO	Uba3-binding protein but1	14623327	But1 and But2 proteins bind to Uba3, a catalytic subunit of E1 for neddylation, in fission yeast.

Q09150	REC14_SCHPO	Meiotic recombination protein rec14	9258671	A WD repeat protein, Rec14, essential for meiotic recombination in Schizosaccharomyces pombe.

O60725	ICMT_HUMAN	Protein-S-isoprenylcysteine O-methyltransferase	9614111	Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum.

P48380	RFX3_HUMAN	Transcription factor RFX3	12411430	Role for RFX transcription factors in non-neuronal cell-specific inactivation of the microtubule-associated protein MAP1A promoter.

P40484	MOB1_YEAST	DBF2 kinase activator protein MOB1	11434459	Regulation of the localization of Dbf2 and Mob1 during cell division of Saccharomyces cerevisiae.

Q9Y265	RUVB1_HUMAN	RuvB-like 1	15960975	Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

Q91YI1	ATG13_MOUSE	Autophagy-related protein 13	19258318	ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy.

O74547	BIT61_SCHPO	Target of rapamycin complex 2 subunit bit61	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9P0K8	FOXJ2_HUMAN	Forkhead box protein J2	10966786	FHX.L and FHX.S, two isoforms of the human fork-head factor FHX (FOXJ2) with differential activity.

Q9D3G9	RHOH_MOUSE	Rho-related GTP-binding protein RhoH	17028588	RhoH GTPase recruits and activates Zap70 required for T cell receptor signaling and thymocyte development.

Q969W9	PMEPA_HUMAN	Transmembrane prostate androgen-induced protein	12907594	PMEPA1, an androgen-regulated NEDD4-binding protein, exhibits cell growth inhibitory function and decreased expression during prostate cancer progression.

Q01973	ROR1_HUMAN	Tyrosine-protein kinase transmembrane receptor ROR1	8875995	Human neural tissues express a truncated Ror1 receptor tyrosine kinase, lacking both extracellular and transmembrane domains.

P47811	MK14_MOUSE	Mitogen-activated protein kinase 14	10943842	Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis.

O35763	MOES_RAT	Moesin	10945828	Cloning and cellular localization of the rat mast cell 78-kDa protein phosphorylated in response to the mast cell 'stabilizer' cromolyn.

Q90Z10	RL13_DANRE	60S ribosomal protein L13	15138505	Many ribosomal protein genes are cancer genes in zebrafish.

P38073	EDS1_YEAST	Transcriptional regulatory protein EDS1	19111667	A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters.

Q9QUR6	PPCE_MOUSE	Prolyl endopeptidase	9538240	cDNA cloning of mouse prolyl endopeptidase and its involvement in DNA synthesis by Swiss 3T3 cells.

Q9Y230	RUVB2_HUMAN	RuvB-like 2	10428817	TIP49b, a new RuvB-like DNA helicase, is included in a complex together with another RuvB-like DNA helicase, TIP49a.

P07323	ENOG_RAT	Gamma-enolase	15041191	Localization of enolase in synaptic plasma membrane as an alphagamma heterodimer in rat brain.

Q7TSY4	ZP3R_RAT	Zona pellucida sperm-binding protein 3 receptor	12737520	Cloning of rat sp56, the homologue of mouse sperm ZP3 receptor- sp56.

Q58G59	KIF7_DANRE	Kinesin-like protein kif7	15647323	A homologue of the Drosophila kinesin-like protein Costal2 regulates Hedgehog signal transduction in the vertebrate embryo.

Q13686	ALKB1_HUMAN	Alkylated DNA repair protein alkB homolog 1	8600462	Molecular cloning and functional analysis of a human cDNA encoding an Escherichia coli AlkB homolog, a protein involved in DNA alkylation damage repair.

P35467	S10A1_RAT	Protein S100-A1	19910580	S100B interaction with the receptor for advanced glycation end products (RAGE): a novel receptor-mediated mechanism for myocyte apoptosis postinfarction.

P17629	HPR1_YEAST	THO complex subunit HPR1	12093753	The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability.

P97531	CIP4_RAT	Cdc42-interacting protein 4	8954095	Molecular cloning of a novel rat salt-tolerant protein by functional complementation in yeast.

P40558	CFD1_YEAST	Cytosolic Fe-S cluster assembly factor CFD1	12970194	A novel eukaryotic factor for cytosolic Fe-S cluster assembly.

Q6AZY7	SCAR3_HUMAN	Scavenger receptor class A member 3	9580669	CSR, a scavenger receptor-like protein with a protective role against cellular damage causedby UV irradiation and oxidative stress.

Q92934	BAD_HUMAN	Bcl2 antagonist of cell death	17270021	Proto-oncogene, Pim-3 with serine/threonine kinase activity, is aberrantly expressed in human colon cancer cells and can prevent Bad- mediated apoptosis.

Q1MTR4	CTI6_SCHPO	Putative histone deacetylase complex subunit cti6	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O00180	KCNK1_HUMAN	Potassium channel subfamily K member 1	8605869	TWIK-1, a ubiquitous human weakly inward rectifying K+ channel with a novel structure.

P31276	HXC13_HUMAN	Homeobox protein Hox-C13	10835276	Selection of homeotic proteins for binding to a human DNA replication origin.

Q07490	CD24_RAT	Signal transducer CD24	9004038	CD24 (heat stable antigen, nectadrin), a novel keratinocyte differentiation marker, is preferentially expressed in areas of the hair follicle containing the colony-forming cells.

O64645	SOC1_ARATH	MADS-box protein SOC1	18339670	Direct interaction of AGL24 and SOC1 integrates flowering signals in Arabidopsis.

Q9Y265	RUVB1_HUMAN	RuvB-like 1	9813143	Identification and characterization of the ubiquitously occurring nuclear matrix protein NMP 238.

P30613	KPYR_HUMAN	Pyruvate kinase isozymes R/L	3126495	Human liver type pyruvate kinase: complete amino acid sequence and the expression in mammalian cells.

P25791	RBTN2_HUMAN	Rhombotin-2	1923511	TTG-2, a new gene encoding a cysteine-rich protein with the LIM motif, is overexpressed in acute T-cell leukaemia with the t(11;14)(p13;q11).

P32121	ARRB2_HUMAN	Beta-arrestin-2	16820410	Novel function of beta-arrestin2 in the nucleus of mature spermatozoa.

Q3V1T4	P3H1_MOUSE	Prolyl 3-hydroxylase 1	10951563	Gros1, a potential growth suppressor on chromosome 1: its identity to basement membrane-associated proteoglycan, leprecan.

Q14191	WRN_HUMAN	Werner syndrome ATP-dependent helicase	16673358	The spectrum of WRN mutations in Werner syndrome patients.

Q63175	SERC5_RAT	Serine incorporator 5	16120614	Serinc, an activity-regulated protein family, incorporates serine into membrane lipid synthesis.

P33322	CBF5_YEAST	H/ACA ribonucleoprotein complex subunit 4	9472021	The box H + ACA snoRNAs carry Cbf5p, the putative rRNA pseudouridine synthase.

Q03707	SRC1_YEAST	Inner nuclear membrane protein SRC1	11754482	SRC1: an intron-containing yeast gene involved in sister chromatid segregation.

P46425	GSTP2_MOUSE	Glutathione S-transferase P 2	7982937	Two murine GSTpi genes are arranged in tandem and are differentially expressed.

P55347	PKNX1_HUMAN	Homeobox protein PKNOX1	9143494	Cloning of a novel homeobox-containing gene, PKNOX1, and mapping to human chromosome 21q22.3.

Q9H553	ALG2_HUMAN	Alpha-1,3-mannosyltransferase ALG2	12684507	A new type of congenital disorders of glycosylation (CDG-Ii) provides new insights into the early steps of dolichol-linked oligosaccharide biosynthesis.

P21957	OPI1_YEAST	Transcriptional repressor OPI1	1985968	The OPI1 gene of Saccharomyces cerevisiae, a negative regulator of phospholipid biosynthesis, encodes a protein containing polyglutamine tracts and a leucine zipper.

Q9VIQ0	SNPF_DROME	Short neuropeptide F	15385546	Drosophila short neuropeptide F regulates food intake and body size.

Q91Z69	SRGP1_MOUSE	SLIT-ROBO Rho GTPase-activating protein 1	11672528	Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway.

Q86VQ3	TXND2_HUMAN	Thioredoxin domain-containing protein 2	11399755	Characterization of Sptrx, a novel member of the thioredoxin family specifically expressed in human spermatozoa.

P32607	RTG1_YEAST	Retrograde regulation protein 1	8422683	RTG1 and RTG2: two yeast genes required for a novel path of communication from mitochondria to the nucleus.

P32898	CYM1_YEAST	Mitochondrial presequence protease	14562095	Global analysis of protein localization in budding yeast.

Q15072	OZF_HUMAN	Zinc finger protein OZF	8665923	Identification, nuclear localization, and binding activities of OZF, a human protein solely composed of zinc-finger motifs.

Q60611	SATB1_MOUSE	DNA-binding protein SATB1	15814699	A role for SATB1, a nuclear matrix association region-binding protein, in the development of CD8SP thymocytes and peripheral T lymphocytes.

O08725	GHSR_RAT	Growth hormone secretagogue receptor type 1	9092793	Molecular analysis of rat pituitary and hypothalamic growth hormone secretagogue receptors.

Q7KRY7	LAP4_DROME	Protein lap4	12930751	Scribble is essential for olfactory behavior in Drosophila melanogaster.

Q9VM09	GR28A_DROME	Putative gustatory receptor 28a	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

Q62011	PDPN_MOUSE	Podoplanin	12032185	Cloning and expression of the mouse glomerular podoplanin homologue gp38P.

P69874	POTA_ECOLI	Spermidine/putrescine import ATP-binding protein PotA	7592703	Spermidine-preferential uptake system in Escherichia coli. ATP hydrolysis by PotA protein and its association with membranes.

Q9WUJ3	MYOME_RAT	Myomegalin	11134006	Myomegalin is a novel protein of the Golgi/centrosome that interacts with a cyclic nucleotide phosphodiesterase.

O60508	PRP17_HUMAN	Pre-mRNA-processing factor 17	9524131	Human homologs of yeast prp16 and prp17 reveal conservation of the mechanism for catalytic step II of pre-mRNA splicing.

Q9JIH2	NUP50_MOUSE	Nuclear pore complex protein Nup50	10891500	Characterization and targeted disruption of murine nup50, a p27(Kip1)-interacting component of the nuclear pore complex.

Q07732	ADY3_YEAST	Accumulates dyads protein 3	11742972	Prospore membrane formation linked to the leading edge protein (LEP) coat assembly.

Q3SWS9	JKIP1_RAT	Janus kinase and microtubule-interacting protein 1	17532644	Marlin-1 and conventional kinesin link GABAB receptors to the cytoskeleton and regulate receptor transport.

Q9BYM8	UB7I3_HUMAN	RanBP-type and C3HC4-type zinc finger-containing protein 1	18711448	Negative feedback regulation of cellular antiviral signaling by RBCK1-mediated degradation of IRF3.

Q8C1A5	THOP1_MOUSE	Thimet oligopeptidase	10969067	The neuropeptide processing enzyme EC 3.4.24.15 is modulated by protein kinase A phosphorylation.

Q5JPF3	AN36C_HUMAN	Ankyrin repeat domain-containing protein 36C	8608414	Inhibitors of renal epithelial phosphate transport in tumor-induced osteomalacia and uremia.

O81275	CSK2D_ARATH	Casein kinase II subunit beta-3	10535927	The protein kinase CK2 is involved in regulation of circadian rhythms in Arabidopsis.

Q9LV85	CPR5_ARATH	Protein CPR-5	11846876	Identification of a novel gene HYS1/CPR5 that has a repressive role in the induction of leaf senescence and pathogen-defence responses in Arabidopsis thaliana.

Q9V496	APLP_DROME	Apolipophorins	15875013	Lipoprotein particles are required for Hedgehog and Wingless signalling.

Q23500	ACOC_CAEEL	Probable cytoplasmic aconitate hydratase	12438312	Cytosolic aconitase and ferritin are regulated by iron in Caenorhabditis elegans.

Q9LVI8	GLN13_ARATH	Glutamine synthetase cytosolic isozyme 1-3	10482686	Carbon and amino acids reciprocally modulate the expression of glutamine synthetase in Arabidopsis.

P53099	TPN1_YEAST	Vitamin B6 transporter TPN1	12649274	Tpn1p, the plasma membrane vitamin B6 transporter of Saccharomyces cerevisiae.

P35054	TGBR3_PIG	Transforming growth factor beta receptor type 3	1333192	Molecular cloning and characterization of the human and porcine transforming growth factor-beta type III receptors.

P39745	SUR1_CAEEL	Mitogen-activated protein kinase mpk-1	8299935	Suppression of activated Let-60 ras protein defines a role of Caenorhabditis elegans Sur-1 MAP kinase in vulval differentiation.

Q9LPW7	AFB3_ARATH	Protein AUXIN SIGNALING F-BOX 3	15917797	The F-box protein TIR1 is an auxin receptor.

Q96PD7	DGAT2_HUMAN	Diacylglycerol O-acyltransferase 2	11481335	Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members.

P09630	HXC6_HUMAN	Homeobox protein Hox-C6	8870653	Cloning and expression of a new HOXC6 transcript encoding a repressing protein.

Q14094	CCNI_HUMAN	Cyclin-I	9705831	Expression of a novel isoform of cyclin I in human testis.

Q61301	CTNA2_MOUSE	Catenin alpha-2	15034585	Stability of dendritic spines and synaptic contacts is controlled by alpha N-catenin.

Q9FJW6	PP451_ARATH	Pentatricopeptide repeat-containing protein At5g67570, chloroplastic	18400937	The pentratricopeptide repeat protein DELAYED GREENING1 is involved in the regulation of early chloroplast development and chloroplast gene expression in Arabidopsis.

P13185	KIN1_YEAST	Serine/threonine protein kinase KIN1	8020610	KIN1 and KIN2 protein kinases localize to the cytoplasmic face of the yeast plasma membrane.

O55000	PP1RA_RAT	Serine/threonine-protein phosphatase 1 regulatory subunit 10	9461602	Isolation and characterization of PNUTS, a putative protein phosphatase 1 nuclear targeting subunit.

O70239	AXN1_RAT	Axin-1	9482734	Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta- dependent phosphorylation of beta-catenin.

P08684	CP3A4_HUMAN	Cytochrome P450 3A4	3460094	Complete cDNA sequence of a cytochrome P-450 inducible by glucocorticoids in human liver.

P30859	ARTI_ECOLI	Putative ABC transporter arginine-binding protein 2	8801422	A third periplasmic transport system for L-arginine in Escherichia coli: molecular characterization of the artPIQMJ genes, arginine binding and transport.

Q12256	TPO4_YEAST	Polyamine transporter 4	12562762	Localization and function of the yeast multidrug transporter Tpo1p.

Q07812	BAX_HUMAN	Apoptosis regulator BAX	11912183	The expression of a new variant of the pro-apoptotic molecule Bax, Baxpsi, is correlated with an increased survival of glioblastoma multiforme patients.

Q9UM07	PADI4_HUMAN	Protein-arginine deiminase type-4	10488123	Molecular characterization of peptidylarginine deiminase in HL-60 cells induced by retinoic acid and 1alpha,25-dihydroxyvitamin D(3).

Q9DCH4	EIF3F_MOUSE	Eukaryotic translation initiation factor 3 subunit F	17581632	Reconstitution reveals the functional core of mammalian eIF3.

P51649	SSDH_HUMAN	Succinate-semialdehyde dehydrogenase, mitochondrial	9683595	Two exon-skipping mutations as the molecular basis of succinic semialdehyde dehydrogenase deficiency (4-hydroxybutyric aciduria).

P31016	DLG4_RAT	Disks large homolog 4	9115257	SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density.

P53946	ARP5_YEAST	Actin-related protein 5	12887900	Involvement of actin-related proteins in ATP-dependent chromatin remodeling.

Q8IUC6	TCAM1_HUMAN	TIR domain-containing adapter molecule 1	12761501	Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.

Q32WR5	BL1S2_RAT	Biogenesis of lysosome-related organelles complex-1 subunit 2	16176350	RSEP1 is a novel gene with functional involvement in neuropathic pain behaviour.

P93740	NUD23_ARATH	Nudix hydrolase 23, chloroplastic	18815383	Molecular characterization of organelle-type Nudix hydrolases in Arabidopsis.

Q10426	RIK1_SCHPO	Chromatin modification-related protein rik1	15197176	The fission yeast heterochromatin protein Rik1 is required for telomere clustering during meiosis.

O96904	TBC12_DICDI	Drainin	10369671	Drainin required for membrane fusion of the contractile vacuole in Dictyostelium is the prototype of a protein family also represented in man.

P83323	RIP_SIRGR	Ribosome-inactivating protein momorgrosvin	11205869	Isolation and characterization of a new ribosome inactivating protein, momorgrosvin, from seeds of the monk's fruit Momordica grosvenorii.

P08620	FGF4_HUMAN	Fibroblast growth factor 4	2959959	Genomic sequence of hst, a transforming gene encoding a protein homologous to fibroblast growth factors and the int-2-encoded protein.

P79960	APJA_XENLA	Apelin receptor A	16750822	Apelin, the ligand for the endothelial G-protein-coupled receptor, APJ, is a potent angiogenic factor required for normal vascular development of the frog embryo.

P83059	KNL2_BOMOR	Kininogen-2	12217414	Bradykinins and their precursor cDNAs from the skin of the fire- bellied toad (Bombina orientalis).

O00268	TAF4_HUMAN	Transcription initiation factor TFIID subunit 4	15735663	A functional interaction between ATF7 and TAF12 that is modulated by TAF4.

P41227	NAA10_HUMAN	N-alpha-acetyltransferase 10, NatA catalytic subunit	7981673	Isolation of new genes in distal Xq28: transcriptional map and identification of a human homologue of the ARD1 N-acetyl transferase of Saccharomyces cerevisiae.

P12004	PCNA_HUMAN	Proliferating cell nuclear antigen	15225546	A defined human system that supports bidirectional mismatch-provoked excision.

Q12791	KCMA1_HUMAN	Calcium-activated potassium channel subunit alpha-1	7993625	Cloning, expression, and distribution of functionally distinct Ca(2+)-activated K+ channel isoforms from human brain.

Q65CL1	CTNA3_MOUSE	Catenin alpha-3	11590244	AlphaT-catenin: a novel tissue-specific beta-catenin-binding protein mediating strong cell-cell adhesion.

O43196	MSH5_HUMAN	MutS protein homolog 5	9787078	Cloning and characterization of the human and Caenorhabditis elegans homologs of the Saccharomyces cerevisiae MSH5 gene.

P83256	TXDP1_PIRLC	Delta-amaurobitoxin-Pl1a	10971590	Isolation, synthesis and pharmacological characterization of delta- palutoxins IT, novel insecticidal toxins from the spider Paracoelotes luctuosus (Amaurobiidae).

Q12986	NFX1_HUMAN	Transcriptional repressor NF-X1	7964459	A novel cysteine-rich sequence-specific DNA-binding protein interacts with the conserved X-box motif of the human major histocompatibility complex class II genes via a repeated Cys-His domain and functions as a transcriptional repressor.

Q6DN14	MCTP1_HUMAN	Multiple C2 and transmembrane domain-containing protein 1	15528213	Evolutionarily conserved multiple C2 domain proteins with two transmembrane regions (MCTPs) and unusual Ca2+ binding properties.

Q12796	PNRC1_HUMAN	Proline-rich nuclear receptor coactivator 1	7578250	Cloning a cDNA from human NK/T cells which codes for a protein with high proline content.

Q6WNK7	SUS1_YEAST	Protein SUS1	14718168	Sus1, a functional component of the SAGA histone acetylase complex and the nuclear pore-associated mRNA export machinery.

P04692	TPM1_RAT	Tropomyosin alpha-1 chain	2022655	Four fibroblast tropomyosin isoforms are expressed from the rat alpha-tropomyosin gene via alternative RNA splicing and the use of two promoters.

Q9R0E0	CEGT_RAT	Ceramide glucosyltransferase	10393098	Histidine-193 of rat glucosylceramide synthase resides in a UDP- glucose- and inhibitor (D-threo-1-phenyl-2-decanoylamino-3- morpholinopropan-1-ol)-binding region: a biochemical and mutational study.

P36406	TRI23_HUMAN	E3 ubiquitin-protein ligase TRIM23	15684077	E3 ubiquitin ligase activity of the trifunctional ARD1 (ADP- ribosylation factor domain protein 1).

P08970	SUHW_DROME	Protein suppressor of hairy wing	16209949	The ubiquitin ligase dTopors directs the nuclear organization of a chromatin insulator.

P97554	DNJB9_RAT	DnaJ homolog subfamily B member 9	11525638	Upregulation of the cochaperone mdg1 in endothelial cells is induced by stress and during in vitro angiogenesis.

P43609	RSC8_YEAST	Chromatin structure-remodeling complex protein RSC8	16204215	The RSC chromatin remodeling complex bears an essential fungal- specific protein module with broad functional roles.

Q09014	NCF1_MOUSE	Neutrophil cytosol factor 1	9490028	Functional modules and expression of mouse p40(phox) and p67(phox), SH3-domain-containing proteins involved in the phagocyte NADPH oxidase complex.

P51617	IRAK1_HUMAN	Interleukin-1 receptor-associated kinase 1	8599092	IRAK: a kinase associated with the interleukin-1 receptor.

P32571	UBP4_YEAST	Ubiquitin carboxyl-terminal hydrolase 4	8247125	The yeast DOA4 gene encodes a deubiquitinating enzyme related to a product of the human tre-2 oncogene.

Q9Y6N1	COX11_HUMAN	Cytochrome c oxidase assembly protein COX11, mitochondrial	9878253	Identification and characterization of human cDNAs specific to BCS1, PET112, SCO1, COX15, and COX11, five genes involved in the formation and function of the mitochondrial respiratory chain.

Q9C966	IAA15_ARATH	Auxin-responsive protein IAA15	12036262	Genetics of Aux/IAA and ARF action in plant growth and development.

P77211	CUSC_ECOLI	Cation efflux system protein cusC	12813074	Molecular analysis of the copper-transporting efflux system CusCFBA of Escherichia coli.

Q8VHX6	FLNC_MOUSE	Filamin-C	16914736	Loss of FilaminC (FLNc) results in severe defects in myogenesis and myotube structure.

Q03112	EVI1_HUMAN	MDS1 and EVI1 complex locus protein EVI1	15897867	Oligomerization of Evi-1 regulated by the PR domain contributes to recruitment of corepressor CtBP.

P12611	WHI2_YEAST	Growth regulation protein	12090248	Yeast Whi2 and Psr1-phosphatase form a complex and regulate STRE- mediated gene expression.

Q92481	AP2B_HUMAN	Transcription factor AP-2-beta	12072434	Transcription factor AP-2 interacts with the SUMO-conjugating enzyme UBC9 and is sumolated in vivo.

P84911	CYT1_CAPHI	Cystatin-1	16257555	Isolation, characterization and kinetics of goat cystatins.

P21860	ERBB3_HUMAN	Receptor tyrosine-protein kinase erbB-3	17701904	Lethal congenital contractural syndrome type 2 (LCCS2) is caused by a mutation in ERBB3 (Her3), a modulator of the phosphatidylinositol-3- kinase/Akt pathway.

P0AFW8	ROF_ECOLI	Protein rof	9723924	An Escherichia coli gene (yaeO) suppresses temperature-sensitive mutations in essential genes by modulating Rho-dependent transcription termination.

P62084	RS7_DANRE	40S ribosomal protein S7	15138505	Many ribosomal protein genes are cancer genes in zebrafish.

Q789F3	MAF_CHICK	Transcription factor Maf	11036080	A set of Hox proteins interact with the Maf oncoprotein to inhibit its DNA binding, transactivation, and transforming activities.

P18824	ARM_DROME	Armadillo segment polarity protein	9635189	Roles of Armadillo, a Drosophila catenin, during central nervous system development.

Q9P7A0	SGO1_SCHPO	Shugoshin-1	14730319	The conserved kinetochore protein shugoshin protects centromeric cohesion during meiosis.

P51797	CLCN6_HUMAN	Chloride transport protein 6	8543009	ClC-6 and ClC-7 are two novel broadly expressed members of the CLC chloride channel family.

O95777	NAA38_HUMAN	N-alpha-acetyltransferase 38, NatC auxiliary subunit	10523320	A doughnut-shaped heteromer of human Sm-like proteins binds to the 3'-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro.

Q9I7U4	TITIN_DROME	Titin	10629221	Requirements of Kettin, a giant muscle protein highly conserved in overall structure in evolution, for normal muscle function, viability, and flight activity of Drosophila.

Q12283	FABD_YEAST	Malonyl CoA-acyl carrier protein transacylase, mitochondrial	9388293	Two genes of the putative mitochondrial fatty acid synthase in the genome of Saccharomyces cerevisiae.

Q9ZUT3	ALS3_ARATH	Protein ALUMINUM SENSITIVE 3	15659095	ALS3 encodes a phloem-localized ABC transporter-like protein that is required for aluminum tolerance in Arabidopsis.

O46341	A6_DROME	Protein a6	10546111	Comparison of the molecular and genetic map of the 2B6-2B7-8 of Drosophila melanogaster X-chromosome.

Q9UDY8	MALT1_HUMAN	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	11090634	Identification of paracaspases and metacaspases. Two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma.

P02654	APOC1_HUMAN	Apolipoprotein C-I	17339654	Apolipoprotein C-I binds free fatty acids and reduces their intracellular esterification.

Q12106	YO228_YEAST	Uncharacterized protein YOR228C	14562095	Global analysis of protein localization in budding yeast.

Q9UTI4	MOA1_SCHPO	Monopolar attachment protein 1	16325576	The kinetochore protein moa1 enables cohesion-mediated monopolar attachment at meiosis I.

A1L1N5	HN1BA_DANRE	Hepatocyte nuclear factor 1-beta-A	15302404	Two distinct teleost hepatocyte nuclear factor 1 genes, hnf1alpha/tcf1 and hnf1beta/tcf2, abundantly expressed in liver, pancreas, gut and kidney of zebrafish.

Q54BM2	PAP1A_DICDI	Polyadenylate-binding protein 1-A	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P51570	GALK1_HUMAN	Galactokinase	8908517	Fine structure of the human galactokinase GALK1 gene.

Q99321	DDP1_YEAST	Diphosphoinositol polyphosphate phosphohydrolase DDP1	10085096	The Saccharomyces cerevisiae YOR163w gene encodes a diadenosine 5', 5'''-P1,P6-hexaphosphate (Ap6A) hydrolase member of the MutT motif (Nudix hydrolase) family.

Q62893	AMHR2_RAT	Anti-Muellerian hormone type-2 receptor	8119126	A novel member of the transmembrane serine/threonine kinase receptor family is specifically expressed in the gonads and in mesenchymal cells adjacent to the Muellerian duct.

P37058	DHB3_HUMAN	Testosterone 17-beta-dehydrogenase 3	8075637	Male pseudohermaphroditism caused by mutations of testicular 17 beta- hydroxysteroid dehydrogenase 3.

O15530	PDPK1_HUMAN	3-phosphoinositide-dependent protein kinase 1	9637919	Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B.

Q13619	CUL4A_HUMAN	Cullin-4A	12732143	The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage.

P35176	CYPD_YEAST	Peptidyl-prolyl cis-trans isomerase D	8377189	A Saccharomyces cerevisiae cyclophilin resident in the endoplasmic reticulum.

O42843	YFH5_SCHPO	Uncharacterized membrane protein C23A1.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P60595	HIS5_ECOLI	Imidazole glycerol phosphate synthase subunit hisH	8494895	Imidazole glycerol phosphate synthase: the glutamine amidotransferase in histidine biosynthesis.

P49585	PCY1A_HUMAN	Choline-phosphate cytidylyltransferase A	7918629	Primary structure and expression of a human CTP:phosphocholine cytidylyltransferase.

P15169	CBPN_HUMAN	Carboxypeptidase N catalytic chain	2912725	cDNA cloning and complete primary structure of the small, active subunit of human carboxypeptidase N (kininase 1).

P40482	SEC24_YEAST	Protein transport protein SEC24	12239560	Structure of the Sec23/24-Sar1 pre-budding complex of the COPII vesicle coat.

Q99986	VRK1_HUMAN	Serine/threonine-protein kinase VRK1	9344656	Identification of two novel human putative serine/threonine kinases, VRK1 and VRK2, with structural similarity to Vaccinia virus B1R kinase.

Q8N5K1	CISD2_HUMAN	CDGSH iron-sulfur domain-containing protein 2	19580816	Crystal structure of Miner1: The redox-active 2Fe-2S protein causative in Wolfram Syndrome 2.

P84798	DPOD3_BOVIN	DNA polymerase delta subunit 3	10751307	Identification of a fourth subunit of mammalian DNA polymerase delta.

Q12018	CDC53_YEAST	Cell division control protein 53	9499404	Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box protein complexes that regulate cell division and methionine biosynthesis in yeast.

Q9Y4A5	TRRAP_HUMAN	Transformation/transcription domain-associated protein	11418595	E2F transcriptional activation requires TRRAP and GCN5 cofactors.

Q06673	ECM30_YEAST	Protein ECM30	14562095	Global analysis of protein localization in budding yeast.

Q9JIF3	GTR8_MOUSE	Solute carrier family 2, facilitated glucose transporter member 8	11689004	Mouse GLUT8: genomic organization and regulation of expression in 3T3-L1 adipocytes by glucose.

Q9PT61	OTX5B_XENLA	Homeobox protein otx5-B	16903786	Timing the generation of distinct retinal cells by homeobox proteins.

Q04951	SCW10_YEAST	Probable family 17 glucosidase SCW10	9748433	New potential cell wall glucanases of Saccharomyces cerevisiae and their involvement in mating.

P23566	UBC2_SCHPO	Ubiquitin-conjugating enzyme E2 2	12456009	The fission yeast ubiquitin-conjugating enzymes UbcP3, Ubc15, and Rhp6 affect transcriptional silencing of the mating-type region.

Q20930	MIG17_CAEEL	ADAM family mig-17	10864868	A metalloprotease disintegrin that controls cell migration in Caenorhabditis elegans.

P15228	AEP1_MESMA	Toxin BmKAEP	2930463	Purification and N-terminal partial sequence of anti-epilepsy peptide from venom of the scorpion Buthus martensii Karsch.

Q9Y7X4	YGRG_SCHPO	Uncharacterized membrane protein C365.16	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P97528	CNTN6_RAT	Contactin-6	8945756	Novel neural adhesion molecules in the contactin/F3 subgroup of the immunoglobulin superfamily: isolation and characterization of cDNAs from rat brain.

P87244	ALP16_SCHPO	Spindle pole body component alp16	12134075	A fourth component of the fission yeast gamma-tubulin complex, Alp16, is required for cytoplasmic microtubule integrity and becomes indispensable when gamma-tubulin function is compromised.

P35567	CDK1A_XENLA	Cell division protein kinase 1-A	10465793	A novel p34cdc2 binding and activating protein that is necessary and sufficient to trigger G2/M progression in Xenopus oocytes.

Q14683	SMC1A_HUMAN	Structural maintenance of chromosomes protein 1A	12199140	Localization of human SMC1 protein at kinetochores.

P15702	LEUK_MOUSE	Leukosialin	11238599	CD43 functions as a T cell counterreceptor for the macrophage adhesion receptor sialoadhesin (Siglec-1).

O00170	AIP_HUMAN	AH receptor-interacting protein	8972861	XAP2, a novel hepatitis B virus X-associated protein that inhibits X transactivation.

Q8N130	NPT2C_HUMAN	Sodium-dependent phosphate transport protein 2C	11880379	Growth-related renal type II Na/Pi cotransporter.

Q9Z0G9	CLD3_MOUSE	Claudin-3	10601346	Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins.

Q9Y6J6	KCNE2_HUMAN	Potassium voltage-gated channel subfamily E member 2	10219239	MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia.

Q9Y5H8	PCDA3_HUMAN	Protocadherin alpha-3	10380929	A striking organization of a large family of human neural cadherin- like cell adhesion genes.

Q6NXI8	CXXC4_MOUSE	CXXC-type zinc finger protein 4	11113207	Inhibition of the Wnt signaling pathway by Idax, a novel Dvl-binding protein.

P15303	SEC23_YEAST	Protein transport protein SEC23	7593161	Yeast SEC16 gene encodes a multidomain vesicle coat protein that interacts with Sec23p.

Q6AWJ9	PTK7_DROME	Tyrosine-protein kinase-like otk	11604138	The transmembrane protein Off-track associates with Plexins and functions downstream of Semaphorin signaling during axon guidance.

Q9NY61	AATF_HUMAN	Protein AATF	10783144	Identification of a novel partner of RNA polymerase II subunit 11, Che-1, which interacts with and affects the growth suppression function of Rb.

Q64010	CRK_MOUSE	Adapter molecule crk	10854253	Isolation and characterization of novel presenilin binding protein.

P53034	RFC2_DROME	Replication factor C subunit 2	11438670	Loss of cell cycle checkpoint control in Drosophila Rfc4 mutants.

Q06344	ESF1_YEAST	Pre-rRNA-processing protein ESF1	14562095	Global analysis of protein localization in budding yeast.

O42807	FAEA_ASPNG	Feruloyl esterase A	9406381	The faeA genes from Aspergillus niger and Aspergillus tubingensis encode ferulic acid esterases involved in degradation of complex cell wall polysaccharides.

Q9JHW5	VAMP7_RAT	Vesicle-associated membrane protein 7	10459012	VAMP-7 mediates vesicular transport from endosomes to lysosomes.

P62256	UBE2H_HUMAN	Ubiquitin-conjugating enzyme E2 H	20061386	The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.

P21453	S1PR1_HUMAN	Sphingosine 1-phosphate receptor 1	8626678	The inducible G protein-coupled receptor edg-1 signals via the G(i)/mitogen-activated protein kinase pathway.

Q9UKR0	KLK12_HUMAN	Kallikrein-12	11054574	Sequencing and expression analysis of the serine protease gene cluster located in chromosome 19q13 region.

P06800	PTPRC_MOUSE	Receptor-type tyrosine-protein phosphatase C	9148925	Identification of the CD45-associated 116-kDa and 80-kDa proteins as the alpha- and beta-subunits of alpha-glucosidase II.

Q9FYG7	TCP1_ARATH	Transcription factor TCP1	11470410	Ancient asymmetries in the evolution of flowers.

Q1ZXQ8	MTAA_DICDI	Centrosomal protein 224	12134070	Dictyostelium EB1 is a genuine centrosomal component required for proper spindle formation.

Q91VK4	ITM2C_MOUSE	Integral membrane protein 2C	14592447	bri3, a novel gene, participates in tumor necrosis factor-alpha- induced cell death.

Q91WW2	MRGA4_MOUSE	Mas-related G-protein coupled receptor member A4	11551509	A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons.

Q00975	CAC1B_HUMAN	Voltage-dependent N-type calcium channel subunit alpha-1B	9030575	Isolation and characterization of the 5'-upstream region of the human N-type calcium channel alpha1B subunit gene. Chromosomal localization and promoter analysis.

Q960V3	MILT_DROME	Trafficking kinesin-binding protein milt	16717129	Axonal transport of mitochondria requires milton to recruit kinesin heavy chain and is light chain independent.

P08047	SP1_HUMAN	Transcription factor Sp1	10976766	A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening.

P26232	CTNA2_HUMAN	Catenin alpha-2	16182284	Nuclear translocation of alphaN-catenin by the novel zinc finger transcriptional repressor ZASC1.

P36209	STS1_SCHPO	Delta(24(24(1)))-sterol reductase	1320960	Fission yeast sts1+ gene encodes a protein similar to the chicken lamin B receptor and is implicated in pleiotropic drug-sensitivity, divalent cation-sensitivity, and osmoregulation.

Q92730	RND1_HUMAN	Rho-related GTP-binding protein Rho6	12730235	Direct interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF- mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cells.

Q54AX5	LRRA_DICDI	Leucine-rich repeat protein lrrA	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P33308	MED9_YEAST	Mediator of RNA polymerase II transcription subunit 9	9812975	Identification of new mediator subunits in the RNA polymerase II holoenzyme from Saccharomyces cerevisiae.

P62158	CALM_HUMAN	Calmodulin	16127172	Calcium/calmodulin regulates ubiquitination of the ubiquitin-specific protease TRE17/USP6.

Q14565	DMC1_HUMAN	Meiotic recombination protein DMC1/LIM15 homolog	8602360	The mouse and human homologs of DMC1, the yeast meiosis-specific homologous recombination gene, have a common unique form of exon- skipped transcript in meiosis.

O35569	NRG2_RAT	Pro-neuregulin-2, membrane-bound isoform	9348101	A novel brain-derived member of the epidermal growth factor family that interacts with ErbB3 and ErbB4.

P87314	HIR1_SCHPO	Protein hir1	16428807	Hip3 interacts with the HIRA proteins Hip1 and Slm9 and is required for transcriptional silencing and accurate chromosome segregation.

Q6NVD9	BFSP2_MOUSE	Phakinin	12573667	Knockout of the intermediate filament protein CP49 destabilises the lens fibre cell cytoskeleton and decreases lens optical quality, but does not induce cataract.

O08837	CDC5L_RAT	Cell division cycle 5-related protein	11884640	DAP-like kinase interacts with the rat homolog of Schizosaccharomyces pombe CDC5 protein, a factor involved in pre-mRNA splicing and required for G2/M phase transition.

P23255	TAF2_YEAST	Transcription initiation factor TFIID subunit 2	10788514	Identification of two novel TAF subunits of the yeast Saccharomyces cerevisiae TFIID complex.

P51148	RAB5C_HUMAN	Ras-related protein Rab-5C	8646882	Isolation and mapping of a human gene (RABL) encoding a small GTP- binding protein homologous to the Ras-related RAB gene.

O42654	MU134_SCHPO	Meiotically up-regulated gene 134 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O59809	IMA3_SCHPO	Probable importin c550.11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q7TS99	HELT_MOUSE	Hairy and enhancer of split-related protein HELT	15071116	Identification of a novel basic helix-loop-helix gene, Heslike, and its role in GABAergic neurogenesis.

Q9C1W4	PMP3_SCHPO	Plasma membrane proteolipid 3	16603158	The fission yeast stress MAPK cascade regulates the pmp3+ gene that encodes a highly conserved plasma membrane protein.

P32378	COQ2_YEAST	Para-hydroxybenzoate--polyprenyltransferase, mitochondrial	1740455	COQ2 is a candidate for the structural gene encoding para- hydroxybenzoate:polyprenyltransferase.

Q8BIA3	MKX_MOUSE	Homeobox protein Mohawk	16408284	Mohawk is a novel homeobox gene expressed in the developing mouse embryo.

Q8ST83	PHO_DROME	Polycomb protein PHO	16618800	A Polycomb group protein complex with sequence-specific DNA-binding and selective methyl-lysine-binding activities.

Q12001	ALG6_YEAST	Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase	8877369	Isolation of the ALG6 locus of Saccharomyces cerevisiae required for glucosylation in the N-linked glycosylation pathway.

P43255	CSN8_ARATH	COP9 signalosome complex subunit 8	8689678	The COP9 complex, a novel multisubunit nuclear regulator involved in light control of a plant developmental switch.

P61837	PIP11_ARATH	Aquaporin PIP1-1	7920711	Water channels in the plant plasma membrane cloned by immunoselection from a mammalian expression system.

P33313	CNS1_YEAST	Hsp70/Hsp90 co-chaperone CNS1	9819421	CNS1 encodes an essential p60/Sti1 homolog in Saccharomyces cerevisiae that suppresses cyclophilin 40 mutations and interacts with Hsp90.

Q01501	VDAC_DICDI	Mitochondrial outer membrane protein porin	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q949P1	ABAH1_ARATH	Abscisic acid 8'-hydroxylase 1	16543410	CYP707A1 and CYP707A2, which encode abscisic acid 8'-hydroxylases, are indispensable for proper control of seed dormancy and germination in Arabidopsis.

Q9USX0	PVG3_SCHPO	Beta-1,3-galactosyltransferase pvg3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P41390	PUR1_SCHPO	Amidophosphoribosyltransferase	8082193	The ade4 gene of Schizosaccharomyces pombe: cloning, sequence and regulation.

Q9UBD6	RHCG_HUMAN	Ammonium transporter Rh type C	10852913	Characterization of human RhCG and mouse Rhcg as novel nonerythroid Rh glycoprotein homologues predominantly expressed in kidney and testis.

P70180	ANPRC_MOUSE	Atrial natriuretic peptide receptor 3	10377427	The natriuretic peptide clearance receptor locally modulates the physiological effects of the natriuretic peptide system.

Q8WZI8	FAEB_ASPNG	Feruloyl esterase B	11931668	The Aspergillus niger faeB gene encodes a second feruloyl esterase involved in pectin and xylan degradation and is specifically induced in the presence of aromatic compounds.

P54802	ANAG_HUMAN	Alpha-N-acetylglucosaminidase	8650226	The molecular basis of Sanfilippo syndrome type B.

Q95RA8	MOB1_DROME	Mps one binder kinase activator-like 1	15975907	Drosophila Mob family proteins interact with the related tricornered (Trc) and warts (Wts) kinases.

P0A8D0	NRDR_ECOLI	Transcriptional repressor NrdR	17496099	NrdR controls differential expression of the Escherichia coli ribonucleotide reductase genes.

O88653	MPKS1_MOUSE	Mitogen-activated protein kinase scaffold protein 1	15263099	Crystal structure of the p14/MP1 scaffolding complex: how a twin couple attaches mitogen-activated protein kinase signaling to late endosomes.

Q60821	ZBT17_MOUSE	Zinc finger and BTB domain-containing protein 17	14560010	Miz1 is required for early embryonic development during gastrulation.

Q9Y217	MTMR6_HUMAN	Myotubularin-related protein 6	9736772	Characterization of the myotubularin dual specificity phosphatase gene family from yeast to human.

P87060	POP1_SCHPO	WD repeat-containing protein pop1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8NF64	ZMIZ2_HUMAN	Zinc finger MIZ domain-containing protein 2	16051670	hZimp7, a novel PIAS-like protein, enhances androgen receptor- mediated transcription and interacts with SWI/SNF-like BAF complexes.

P47818	CCC1_YEAST	Protein CCC1	10713071	CCC1 suppresses mitochondrial damage in the yeast model of Friedreich's ataxia by limiting mitochondrial iron accumulation.

P83790	LED2_PHYAM	Lectin-D2	8987560	Amino acid sequence and some properties of lectin-D from the roots of pokeweed (Phytolacca americana).

Q949Y3	PPA26_ARATH	Bifunctional purple acid phosphatase 26	15539469	The vegetative vacuole proteome of Arabidopsis thaliana reveals predicted and unexpected proteins.

P17568	NDUB7_HUMAN	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

Q12109	SYWC_YEAST	Tryptophanyl-tRNA synthetase, cytoplasmic	9046085	Identification and expression of the Saccharomyces cerevisiae cytoplasmic tryptophanyl-tRNA synthetase gene.

P40379	REC16_SCHPO	Transcriptional activator protein rec16	8168486	A zinc finger protein controls the onset of premeiotic DNA synthesis of fission yeast in a Mei2-independent cascade.

P13224	GP1BB_HUMAN	Platelet glycoprotein Ib beta chain	3353370	The alpha and beta chains of human platelet glycoprotein Ib are both transmembrane proteins containing a leucine-rich amino acid sequence.

Q08733	PIP13_ARATH	Aquaporin PIP1-3	7920711	Water channels in the plant plasma membrane cloned by immunoselection from a mammalian expression system.

Q12221	PUF2_YEAST	mRNA-binding protein PUF2	11101532	The Puf3 protein is a transcript-specific regulator of mRNA degradation in yeast.

Q86GF7	CRUST_PANBO	Crustapain	12869537	Molecular cloning and functional characterization of crustapain: a distinct cysteine proteinase with unique substrate specificity from northern shrimp Pandalus borealis.

Q9P299	COPZ2_HUMAN	Coatomer subunit zeta-2	11056392	Identification and characterization of novel isoforms of COP I subunits.

Q9V4Z9	LINES_DROME	Protein lines	11784087	Drumstick, bowl, and lines are required for patterning and cell rearrangement in the Drosophila embryonic hindgut.

Q04307	RPC10_YEAST	DNA-directed RNA polymerase III subunit RPC10	9869639	The RNA cleavage activity of RNA polymerase III is mediated by an essential TFIIS-like subunit and is important for transcription termination.

Q10253	MUG64_SCHPO	Meiotically up-regulated gene 64 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P97612	FAAH1_RAT	Fatty-acid amide hydrolase 1	12734197	Evidence for distinct roles in catalysis for residues of the serine- serine-lysine catalytic triad of fatty acid amide hydrolase.

P38920	MLH1_YEAST	DNA mismatch repair protein MLH1	11717305	Differential ATP binding and intrinsic ATP hydrolysis by amino- terminal domains of the yeast Mlh1 and Pms1 proteins.

P02461	CO3A1_HUMAN	Collagen alpha-1(III) chain	1672129	G to T transversion at position +5 of a splice donor site causes skipping of the preceding exon in the type III procollagen transcripts of a patient with Ehlers-Danlos syndrome type IV.

Q13586	STIM1_HUMAN	Stromal interaction molecule 1	19632184	An EB1-binding motif acts as a microtubule tip localization signal.

P62136	PP1A_HUMAN	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit	17965019	NOM1 targets protein phosphatase I to the nucleolus.

P06843	SPT2_YEAST	Protein SPT2	2072912	A negative regulator of HO transcription, SIN1 (SPT2), is a nonspecific DNA-binding protein related to HMG1.

Q6IA17	SIGIR_HUMAN	Single Ig IL-1-related receptor	12925853	SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling.

Q9VQU9	BOWEL_DROME	Protein bowel	14573519	Bowl is required downstream of Notch for elaboration of distal limb patterning.

P50475	SYAC_RAT	Alanyl-tRNA synthetase, cytoplasmic	2040280	Alanyl-tRNA synthetase from Escherichia coli, Bombyx mori and Ratus ratus. Existence of common structural features.

Q15825	ACHA6_HUMAN	Neuronal acetylcholine receptor subunit alpha-6	8906617	Comparative structure of human neuronal alpha 2-alpha 7 and beta 2- beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits.

P04054	PA21B_HUMAN	Phospholipase A2	7060561	Studies on prophospholipase A2 and its enzyme from human pancreatic juice. Catalytic properties and sequence of the N-terminal region.

Q9VTV1	THOC6_DROME	THO complex subunit 6	15133499	Genome-wide analysis of mRNAs regulated by the THO complex in Drosophila.

Q96524	CRY2_ARATH	Cryptochrome-2	10476076	Nuclear localization of the Arabidopsis blue light receptor cryptochrome 2.

P83406	SCBT2_BUTJU	Neurotoxin Tx-2	15067003	Activation of skeletal ryanodine receptors by two novel scorpion toxins from Buthotus judaicus.

P10870	SNF3_YEAST	High-affinity glucose transporter SNF3	2406560	Mutational analysis of the SNF3 glucose transporter of Saccharomyces cerevisiae.

O74386	YNVB_SCHPO	Uncharacterized methyltransferase C3H7.11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9SYT0	ANXD1_ARATH	Annexin D1	16531057	Expression profiling of the Arabidopsis annexin gene family during germination, de-etiolation and abiotic stress.

Q9UUZ3	MANBA_ASPNG	Beta-mannosidase	10553664	Hydrolytic properties of a beta-mannosidase purified from Aspergillus niger.

Q9NX14	NDUBB_HUMAN	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

Q9NPD8	UBE2T_HUMAN	Ubiquitin-conjugating enzyme E2 T	20061386	The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.

Q8VHQ9	ACO11_MOUSE	Acyl-coenzyme A thioesterase 11	11696000	BFIT, a unique acyl-CoA thioesterase induced in thermogenic brown adipose tissue: cloning, organization of the human gene and assessment of a potential link to obesity.

P92208	JNK_DROME	Stress-activated protein kinase JNK	8946916	The Drosophila Jun-N-terminal kinase is required for cell morphogenesis but not for DJun-dependent cell fate specification in the eye.

P18163	ACSL1_RAT	Long-chain-fatty-acid--CoA ligase 1	17478130	Post-translational modifications of rat liver mitochondrial outer membrane proteins identified by mass spectrometry.

P38879	NACA_YEAST	Nascent polypeptide-associated complex subunit alpha	10219998	Initial characterization of the nascent polypeptide-associated complex in yeast.

Q9Y2G9	SBNO2_HUMAN	Protein strawberry notch homolog 2	18025162	A transcriptional repressor and corepressor induced by the STAT3- regulated anti-inflammatory signaling pathway.

Q8GY23	UPL1_ARATH	E3 ubiquitin-protein ligase UPL1	10571878	UPL1 and 2, two 405 kDa ubiquitin-protein ligases from Arabidopsis thaliana related to the HECT-domain protein family.

P69820	ULAC_ECOLI	Ascorbate-specific phosphotransferase enzyme IIA component	12644495	The ascorbate transporter of Escherichia coli.

Q8VI67	SP7_MOUSE	Transcription factor Sp7	11792318	The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation.

P36131	SPC34_YEAST	DASH complex subunit SPC34	15640796	The yeast DASH complex forms closed rings on microtubules.

Q10916	ASM1_CAEEL	Sphingomyelin phosphodiesterase 1	9603947	Caenorhabditis elegans contains two distinct acid sphingomyelinases.

Q13438	OS9_HUMAN	Protein OS-9	18417469	A dual task for the Xbp1-responsive OS-9 variants in the mammalian endoplasmic reticulum: inhibiting secretion of misfolded protein conformers and enhancing their disposal.

P53101	STR3_YEAST	Cystathionine beta-lyase	10821189	Cysteine is essential for transcriptional regulation of the sulfur assimilation genes in Saccharomyces cerevisiae.

O14041	YEY8_SCHPO	Uncharacterized nucleoloar protein C2C4.08	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P87109	YDK2_SCHPO	Probable phospholipase C20G8.02, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P52286	SKP1_YEAST	Suppressor of kinetochore protein 1	9346239	A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p.

Q24338	ESC_DROME	Polycomb protein esc	12771214	The Drosophila Corto protein interacts with Polycomb-group proteins and the GAGA factor.

O95436	NPT2B_HUMAN	Sodium-dependent phosphate transport protein 2B	10610722	Molecular cloning, functional characterization, tissue distribution, and chromosomal localization of a human, small intestinal sodium- phosphate (Na+-Pi) transporter (SLC34A2).

O42478	TLE4_XENLA	Transducin-like enhancer protein 4	17138566	FoxD3 and Grg4 physically interact to repress transcription and induce mesoderm in Xenopus.

P86011	CUTI2_COLGL	Cutinase 2	17043825	Purification and identification of cutinases from Colletotrichum kahawae and Colletotrichum gloeosporioides.

Q9EQH4	TAF8_MOUSE	Transcription initiation factor TFIID subunit 8	11076765	Taube nuss is a novel gene essential for the survival of pluripotent cells of early mouse embryos.

Q62867	GGH_RAT	Gamma-glutamyl hydrolase	8621474	Identification, cloning, and sequencing of a cDNA coding for rat gamma-glutamyl hydrolase.

P08124	COL1_CAEEL	Cuticle collagen 1	2578467	Expression of the Caenorhabditis elegans collagen genes col-1 and col-2 is developmentally regulated.

P01303	NPY_HUMAN	Neuropeptide Y	2427515	Characterization, sequence, and expression of the cloned human neuropeptide Y gene.

P64943	PAFA_MYCTU	Pup--protein ligase	20355727	Prokaryotic ubiquitin-like protein (Pup) is coupled to substrates via the side chain of its C-terminal glutamate.

P32571	UBP4_YEAST	Ubiquitin carboxyl-terminal hydrolase 4	8657109	Coordinating DNA replication to produce one copy of the genome requires genes that act in ubiquitin metabolism.

P38625	GUAA_YEAST	GMP synthase [glutamine-hydrolyzing]	8112582	Cloning and sequencing of the GMP synthetase-encoding gene of Saccharomyces cerevisiae.

Q12149	RRP6_YEAST	Exosome complex exonuclease RRP6	10465791	The yeast exosome and human PM-Scl are related complexes of 3'-->5' exonucleases.

Q04120	TSA2_YEAST	Peroxiredoxin TSA2	10681558	Distinct physiological functions of thiol peroxidase isoenzymes in Saccharomyces cerevisiae.

Q9Y5B0	CTDP1_HUMAN	RNA polymerase II subunit A C-terminal domain phosphatase	9765293	FCP1, the RAP74-interacting subunit of a human protein phosphatase that dephosphorylates the carboxyl-terminal domain of RNA polymerase IIO.

P53179	PALF_YEAST	pH-response regulator protein palF/RIM8	9017390	Proteolytic activation of Rim1p, a positive regulator of yeast sporulation and invasive growth.

P53117	YGO6_YEAST	Uncharacterized protein YGL146C	9046099	The sequence of a nearly unclonable 22.8 kb segment on the left arm chromosome VII from Saccharomyces cerevisiae reveals ARO2, RPL9A, TIP1, MRF1 genes and six new open reading frames.

O94329	PSF2_SCHPO	DNA replication complex GINS protein psf2	16199877	Suppressors of Bir1p (Survivin) identify roles for the chromosomal passenger protein Pic1p (INCENP) and the replication initiation factor Psf2p in chromosome segregation.

Q8R5K4	NOL6_MOUSE	Nucleolar protein 6	11895476	Isolation and characterization of a new nucleolar protein, Nrap, that is conserved from yeast to humans.

Q94F62	BAK1_ARATH	BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1	16473966	The Arabidopsis SOMATIC EMBRYOGENESIS RECEPTOR-LIKE KINASE1 protein complex includes BRASSINOSTEROID-INSENSITIVE1.

P17950	IER2_MOUSE	Immediate early response gene 2 protein	2247083	Pip92: a short-lived, growth factor-inducible protein in BALB/c 3T3 and PC12 cells.

Q9C9W9	ADO3_ARATH	Adagio protein 3	10847687	FKF1, a clock-controlled gene that regulates the transition to flowering in Arabidopsis.

Q5A950	ATG26_CANAL	Sterol 3-beta-glucosyltransferase	10224056	Cloning and functional expression of UGT genes encoding sterol glucosyltransferases from Saccharomyces cerevisiae, Candida albicans, Pichia pastoris, and Dictyostelium discoideum.

Q29983	MICA_HUMAN	MHC class I polypeptide-related sequence A	11224526	Costimulation of CD8alphabeta T cells by NKG2D via engagement by MIC induced on virus-infected cells.

Q93008	USP9X_HUMAN	Probable ubiquitin carboxyl-terminal hydrolase FAF-X	16322459	Chromosome alignment and segregation regulated by ubiquitination of survivin.

P22361	HNF1A_MOUSE	Hepatocyte nuclear factor 1-alpha	11106484	High-resolution structure of the HNF-1alpha dimerization domain.

O95800	GPR75_HUMAN	Probable G-protein coupled receptor 75	10381362	Cloning and characterization of a novel orphan G-protein-coupled receptor localized to human chromosome 2p16.

Q08397	LOXL1_HUMAN	Lysyl oxidase homolog 1	7689553	A novel human cDNA with a predicted protein similar to lysyl oxidase maps to chromosome 15q24-q25.

Q02979	GDE1_YEAST	Glycerophosphodiester phosphodiesterase GDE1	16141200	Glycerophosphocholine-dependent growth requires Gde1p (YPL110c) and Git1p in Saccharomyces cerevisiae.

Q64428	ECHA_RAT	Trifunctional enzyme subunit alpha, mitochondrial	1730633	Novel fatty acid beta-oxidation enzymes in rat liver mitochondria. II. Purification and properties of enoyl-coenzyme A (CoA) hydratase/3- hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase trifunctional protein.

Q4KUS2	UN13A_MOUSE	Protein unc-13 homolog A	10440375	Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles.

O13733	PPK3_SCHPO	Protein kinase domain-containing protein ppk3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q18685	UN112_CAEEL	Protein unc-112	12781130	C. elegans PAT-6/actopaxin plays a critical role in the assembly of integrin adhesion complexes in vivo.

P49146	NPY2R_HUMAN	Neuropeptide Y receptor type 2	7592910	Expression cloning and pharmacological characterization of a human hippocampal neuropeptide Y/peptide YY Y2 receptor subtype.

O00102	UBC7_SCHPO	Ubiquitin-conjugating enzyme E2-18 kDa	19520858	Degradation of sterol regulatory element-binding protein precursor requires the endoplasmic reticulum-associated degradation components Ubc7 and Hrd1 in fission yeast.

P38702	LEU5_YEAST	Mitochondrial carrier protein LEU5	11158296	The yeast mitochondrial carrier Leu5p and its human homologue Graves' disease protein are required for accumulation of coenzyme A in the matrix.

P20457	PRI2_YEAST	DNA primase large subunit	2023935	Mutations in conserved yeast DNA primase domains impair DNA replication in vivo.

O70325	GPX41_MOUSE	Phospholipid hydroperoxide glutathione peroxidase, mitochondrial	12566075	The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults.

Q9UKQ2	ADA28_HUMAN	Disintegrin and metalloproteinase domain-containing protein 28	10587367	Identification, sequence analysis and expression of transcripts encoding a putative metalloproteinase, eMDC II, in human and macaque epididymis.

O88379	BAZ1A_MOUSE	Bromodomain adjacent to zinc finger domain protein 1A	9701556	Capturing novel mouse genes encoding chromosomal and other nuclear proteins.

Q9BXN1	ASPN_HUMAN	Asporin	17827158	Mechanisms for asporin function and regulation in articular cartilage.

Q9CAE3	LDL3_ARATH	Lysine-specific histone demethylase 1 homolog 3	14593187	Regulation of flowering time by histone acetylation in Arabidopsis.

Q8IVG9	HUNIN_HUMAN	Humanin	15153530	Humanin, a newly identified neuroprotective factor, uses the G protein-coupled formylpeptide receptor-like-1 as a functional receptor.

Q93ZR1	ELP3_ARATH	Elongator complex protein 3	15894610	The elongata mutants identify a functional Elongator complex in plants with a role in cell proliferation during organ growth.

Q54KG1	DDX41_DICDI	Probable ATP-dependent RNA helicase ddx41	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

P01283	VIP_RAT	VIP peptides	3838518	Nucleotide sequence divergence and functional constraint in VIP precursor mRNA evolution between human and rat.

Q9UNW1	MINP1_HUMAN	Multiple inositol polyphosphate phosphatase 1	9923613	The human and rat forms of multiple inositol polyphosphate phosphatase: functional homology with a histidine acid phosphatase up- regulated during endochondral ossification.

Q05779	COQ9_YEAST	Ubiquinone biosynthesis protein COQ9, mitochondrial	16027161	COQ9, a new gene required for the biosynthesis of coenzyme Q in Saccharomyces cerevisiae.

P13497	BMP1_HUMAN	Bone morphogenetic protein 1	3201241	Novel regulators of bone formation: molecular clones and activities.

P08236	BGLR_HUMAN	Beta-glucuronidase	3468507	Cloning, sequencing, and expression of cDNA for human beta- glucuronidase.

Q9FN92	Y5597_ARATH	Probable receptor-like protein kinase At5g59700	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

O14910	LIN7A_HUMAN	Protein lin-7 homolog A	9482110	The C-terminus of the HTLV-1 Tax oncoprotein mediates interaction with the PDZ domain of cellular proteins.

Q14185	DOCK1_HUMAN	Dedicator of cytokinesis protein 1	12134158	Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex.

Q7YQK4	LAT1_RABIT	Large neutral amino acids transporter small subunit 1	16125134	Site-directed mutagenesis of cysteine residues of large neutral amino acid transporter LAT1.

Q9HC57	WFDC1_HUMAN	WAP four-disulfide core domain protein 1	10967136	The WFDC1 gene encoding ps20 localizes to 16q24, a region of LOH in multiple cancers.

P40554	URM1_YEAST	Ubiquitin-related modifier 1	14551258	Urmylation: a ubiquitin-like pathway that functions during invasive growth and budding in yeast.

Q60177	PSA_METJA	Proteasome subunit alpha	19481527	Structural insights into the regulatory particle of the proteasome from Methanocaldococcus jannaschii.

Q03529	SCS7_YEAST	Ceramide very long chain fatty acid hydroxylase SCS7	9368039	Hydroxylation of Saccharomyces cerevisiae ceramides requires Sur2p and Scs7p.

Q54YL2	DAK_DICDI	Deoxyadenosine kinase	17448496	Dictyostelium discoideum salvages purine deoxyribonucleosides by highly specific bacterial-like deoxyribonucleoside kinases.

P55163	GEX3_CAEEL	Membrane-associated protein gex-3	11922622	Isolation of the interacting molecules with GEX-3 by a novel functional screening.

P43034	LIS1_HUMAN	Platelet-activating factor acetylhydrolase IB subunit alpha	11940666	LIS1, CLIP-170's key to the dynein/dynactin pathway.

P0ADC6	LPTG_ECOLI	Lipopolysaccharide export system permease protein lptG	15919996	Global topology analysis of the Escherichia coli inner membrane proteome.

P43601	ATG18_YEAST	Autophagy-related protein 18	17699591	Atg18 regulates organelle morphology and Fab1 kinase activity independent of its membrane recruitment by phosphatidylinositol 3,5- bisphosphate.

P38116	ARL1_YEAST	ADP-ribosylation factor-like protein 1	12620189	The ARF-like GTPases Arl1p and Arl3p act in a pathway that interacts with vesicle-tethering factors at the Golgi apparatus.

Q8LEK4	TRL21_ARATH	Thioredoxin-like 2-1, chloroplastic	19259774	A novel extended family of stromal thioredoxins.

P78789	YC63_SCHPO	Uncharacterized protein C1919.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P40215	NDH1_YEAST	External NADH-ubiquinone oxidoreductase 1, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P32786	RRN6_YEAST	RNA polymerase I-specific transcription initiation factor RRN6	8887672	A novel 66-kilodalton protein complexes with Rrn6, Rrn7, and TATA- binding protein to promote polymerase I transcription initiation in Saccharomyces cerevisiae.

P32494	NGG1_YEAST	Chromatin-remodeling complexes subunit NGG1	10490601	The ADA complex is a distinct histone acetyltransferase complex in Saccharomyces cerevisiae.

Q6ZHS4	CADH2_ORYSJ	Cinnamyl alcohol dehydrogenase 2	15452707	Structure of the cinnamyl-alcohol dehydrogenase gene family in rice and promoter activity of a member associated with lignification.

Q05B81	PCFT_BOVIN	Proton-coupled folate transporter	17335806	Heme carrier protein 1 (HCP1) expression and functional analysis in the retina and retinal pigment epithelium.

Q9P7Y0	SSR4_SCHPO	SWI/SNF and RSC complexes subunit ssr4	18622392	Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast.

Q91XJ0	CREST_RAT	Calcium-responsive transcription coactivator	19081374	A calcium-dependent switch in a CREST-BRG1 complex regulates activity-dependent gene expression.

Q54TY7	SRFA_DICDI	Serum response factor homolog A	14706699	The MADS-box transcription factor SrfA is required for actin cytoskeleton organization and spore coat stability during Dictyostelium sporulation.

P70196	TRAF6_MOUSE	TNF receptor-associated factor 6	17633018	Characteristics and biological functions of TRAF6.

Q93045	STMN2_HUMAN	Stathmin-2	18452648	BRI3 associates with SCG10 and attenuates NGF-induced neurite outgrowth in PC12 cells.

O88509	DNM3B_MOUSE	DNA (cytosine-5)-methyltransferase 3B	18056424	Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing.

P22523	MUKB_ECOLI	Chromosome partition protein mukB	10545099	Complex formation of MukB, MukE and MukF proteins involved in chromosome partitioning in Escherichia coli.

O35793	GREM1_RAT	Gremlin-1	9234736	Identification of drm, a novel gene whose expression is suppressed in transformed cells and which can inhibit growth of normal but not transformed cells in culture.

Q54RQ1	SODC3_DICDI	Extracellular superoxide dismutase [Cu-Zn] 3	12913271	Multinucleation of the sodC-deficient Dictyostelium discoideum.

P38283	SLI15_YEAST	Inner centromere protein-related protein SLI15	11724818	Functional cooperation of Dam1, Ipl1, and the inner centromere protein (INCENP)-related protein Sli15 during chromosome segregation.

Q14847	LASP1_HUMAN	LIM and SH3 domain protein 1	7589475	Lasp-1 (MLN 50) defines a new LIM protein subfamily characterized by the association of LIM and SH3 domains.

Q96251	ATPO_ARATH	ATP synthase subunit O, mitochondrial	11743114	Proteomic approach to identify novel mitochondrial proteins in Arabidopsis.

Q62315	JARD2_MOUSE	Protein Jumonji	20075857	JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells.

Q8K1Z0	COQ9_MOUSE	Ubiquinone biosynthesis protein COQ9, mitochondrial	14651853	Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.

P97299	SFRP2_MOUSE	Secreted frizzled-related protein 2	9391078	SARPs: a family of secreted apoptosis-related proteins.

P87048	RPN1_SCHPO	26S proteasome regulatory subunit rpn1	9325304	Mts4, a non-ATPase subunit of the 26 S protease in fission yeast is essential for mitosis and interacts directly with the ATPase subunit Mts2.

P05059	CMGA_BOVIN	Chromogranin-A	10753865	Antibacterial and antifungal activities of vasostatin-1, the N- terminal fragment of chromogranin A.

O74834	UNG_SCHPO	Uracil-DNA glycosylase	12810074	A fission yeast homologue of the human uracil-DNA-glycosylase and their roles in causing DNA damage after overexpression.

P10040	CRB_DROME	Protein crumbs	11740560	Drosophila Stardust is a partner of Crumbs in the control of epithelial cell polarity.

Q80WJ1	GGN_MOUSE	Gametogenetin	15642376	Yeast two-hybrid screens imply that GGNBP1, GGNBP2 and OAZ3 are potential interaction partners of testicular germ cell-specific protein GGN1.

Q16584	M3K11_HUMAN	Mitogen-activated protein kinase kinase kinase 11	15258589	MLK3 is required for mitogen activation of B-Raf, ERK and cell proliferation.

Q8VI60	SULF1_RAT	Extracellular sulfatase Sulf-1	11895481	Identification of a novel nonlysosomal sulphatase expressed in the floor plate, choroid plexus and cartilage.

Q9Y210	TRPC6_HUMAN	Short transient receptor potential channel 6	15757897	MxA, a member of the dynamin superfamily, interacts with the ankyrin- like repeat domain of TRPC.

Q9Y7Y9	YOD2_SCHPO	Uncharacterized membrane protein C18A7.02c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P78965	GSHR_SCHPO	Glutathione reductase	9287302	Isolation, expression, and regulation of the pgr1(+) gene encoding glutathione reductase absolutely required for the growth of Schizosaccharomyces pombe.

P03956	MMP1_HUMAN	Interstitial collagenase	3027129	Molecular cloning of human synovial cell collagenase and selection of a single gene from genomic DNA.

Q60544	TAF1_MESAU	Transcription initiation factor TFIID subunit 1	8163200	The CCG1/TAFII250 gene is mutated in thermosensitive G1 mutants of the BHK21 cell line derived from golden hamster.

Q9Y4K3	TRAF6_HUMAN	TNF receptor-associated factor 6	18093978	Nuclear tumor necrosis factor receptor-associated factor 6 in lymphoid cells negatively regulates c-Myb-mediated transactivation through small ubiquitin-related modifier-1 modification.

Q07560	CRD1_YEAST	Cardiolipin synthase	9614098	Isolation and characterization of the gene (CLS1) encoding cardiolipin synthase in Saccharomyces cerevisiae.

Q9NS56	TOPRS_HUMAN	E3 ubiquitin-protein ligase Topors	14516784	The DNA topoisomerase I binding protein topors as a novel cellular target for SUMO-1 modification: characterization of domains necessary for subcellular localization and sumolation.

Q91VW5	GOGA4_MOUSE	Golgin subfamily A member 4	12162805	Characterization of mouse tGolgin-1 (golgin-245/trans-Golgi p230/256 kD golgin) and its upregulation during oligodendrocyte development.

O74399	ERB1_SCHPO	Ribosome biogenesis protein erb1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P40478	VDAC2_YEAST	Mitochondrial outer membrane protein porin 2	9315631	Multicopy suppressors of phenotypes resulting from the absence of yeast VDAC encode a VDAC-like protein.

Q6ZY51	PWD_ARATH	Phosphoglucan, water dikinase, chloroplastic	15686522	A novel isoform of glucan, water dikinase phosphorylates pre- phosphorylated alpha-glucans and is involved in starch degradation in Arabidopsis.

Q8BR76	MKS3_MOUSE	Meckelin	19815549	Meckel-Gruber syndrome protein MKS3 is required for endoplasmic reticulum-associated degradation of surfactant protein C.

P25649	AHC2_YEAST	ADA histone acetyltransferase complex component 2	14562095	Global analysis of protein localization in budding yeast.

O75901	RASF9_HUMAN	Ras association domain-containing protein 9	9837933	P-CIP1, a novel protein that interacts with the cytosolic domain of peptidylglycine alpha-amidating monooxygenase, is associated with endosomes.

P61328	FGF12_HUMAN	Fibroblast growth factor 12	10049777	Cloning and characterization of a cDNA encoding a novel fibroblast growth factor preferentially expressed in human heart.

O42933	PMT4_SCHPO	Dolichyl-phosphate-mannose--protein mannosyltransferase 4	15948957	Protein O-mannosylation is crucial for cell wall integrity, septation and viability in fission yeast.

Q03426	KIME_HUMAN	Mevalonate kinase	1377680	Molecular cloning of human mevalonate kinase and identification of a missense mutation in the genetic disease mevalonic aciduria.

Q80UF4	SDCG8_MOUSE	Serologically defined colon cancer antigen 8 homolog	12559564	Identification and characterization of the novel centrosome- associated protein CCCAP.

Q9NSC2	SALL1_HUMAN	Sal-like protein 1	18297069	Mutations in the cyclin family member FAM58A cause an X-linked dominant disorder characterized by syndactyly, telecanthus and anogenital and renal malformations.

Q56YP2	PI5K1_ARATH	Phosphatidylinositol-4-phosphate 5-kinase 1	11672432	AtPIP5K1, an Arabidopsis thaliana phosphatidylinositol phosphate kinase, synthesizes PtdIns(3,4)P(2) and PtdIns(4,5)P(2) in vitro and is inhibited by phosphorylation.

Q9H251	CAD23_HUMAN	Cadherin-23	16679490	Survey of the frequency of USH1 gene mutations in a cohort of Usher patients shows the importance of cadherin 23 and protocadherin 15 genes and establishes a detection rate of above 90%.

Q9JLP1	KHDR3_RAT	KH domain-containing, RNA-binding, signal transduction-associated protein 3	15345239	p59(fyn)-mediated phosphorylation regulates the activity of the tissue-specific splicing factor rSLM-1.

P63321	RALA_MOUSE	Ras-related protein Ral-A	20005108	RalA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling.

Q9JJP6	P63_RAT	Tumor protein 63	11470269	Identification and tissue distribution of novel KET/p63 splice variants.

Q9BUT1	BDH2_HUMAN	3-hydroxybutyrate dehydrogenase type 2	16380372	Characterization of human DHRS6, an orphan short chain dehydrogenase/reductase enzyme: a novel, cytosolic type 2 R-beta- hydroxybutyrate dehydrogenase.

P01781	HV320_HUMAN	Ig heavy chain V-III region GAL	4803843	The primary structure of a monoclonal IgM-immunoglobulin (macroglobulin Gal.), II: the amino acid sequence of the H-chain (mu- type), subgroup H III. Architecture of the complete IgM-molecule.

Q15084	PDIA6_HUMAN	Protein disulfide-isomerase A6	7590364	Cloning and sequencing of the cDNA encoding human P5.

Q9DE14	ATR_XENLA	Serine/threonine-protein kinase atr	16530042	TopBP1 activates the ATR-ATRIP complex.

O94811	TPPP_HUMAN	Tubulin polymerization-promoting protein	18028908	The phosphorylation of p25/TPPP by LIM kinase 1 inhibits its ability to assemble microtubules.

P41391	RNA1_SCHPO	Ran GTPase-activating protein 1	8374168	A functional homologue of the RNA1 gene product in Schizosaccharomyces pombe: purification, biochemical characterization, and identification of a leucine-rich repeat motif.

Q04623	ECM18_YEAST	Protein ECM18	9335584	Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae.

Q03157	APLP1_MOUSE	Amyloid-like protein 1	16314516	Amyloid precursor proteins anchor CPEB to membranes and promote polyadenylation-induced translation.

Q64373	B2CL1_MOUSE	Bcl-2-like protein 1	14499110	The structure of a Bcl-xL/Bim fragment complex: implications for Bim function.

P54280	PMS1_SCHPO	DNA mismatch repair protein pms1	9258673	Mismatch repair in Schizosaccharomyces pombe requires the mutL homologous gene pms1: molecular cloning and functional analysis.

O35567	PUR9_RAT	Bifunctional purine biosynthesis protein PURH	9332377	Molecular cloning and expression of a rat cDNA encoding 5- aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.

P33755	NPL4_YEAST	Nuclear protein localization protein 4	11740563	The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol.

P63005	LIS1_MOUSE	Platelet-activating factor acetylhydrolase IB subunit alpha	11163260	NUDEL is a novel cdk5 substrate that associates with LIS1 and cytoplasmic dynein.

P10622	RLA3_YEAST	60S acidic ribosomal protein P1-beta	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q5TYV4	VIPAR_DANRE	VPS33B-interacting protein	20190753	Mutations in VIPAR cause an arthrogryposis, renal dysfunction and cholestasis syndrome phenotype with defects in epithelial polarization.

Q9JHJ7	TEST_MOUSE	Testisin	11231276	Organization and chromosomal localization of the murine Testisin gene encoding a serine protease temporally expressed during spermatogenesis.

O60187	SID4_SCHPO	Septation initiation protein sid4	10805785	Sid4p is required to localize components of the septation initiation pathway to the spindle pole body in fission yeast.

P40722	SOPD_SALTY	Secreted effector protein sopD	12535274	SopD2 is a novel type III secreted effector of Salmonella typhimurium that targets late endocytic compartments upon delivery into host cells.

P61889	MDH_ECOLI	Malate dehydrogenase	2993232	Isolation and expression of the Escherichia coli gene encoding malate dehydrogenase.

Q02820	NCE1_YEAST	Non-classical export protein 1	8655575	A new pathway for protein export in Saccharomyces cerevisiae.

Q9H340	O51B6_HUMAN	Olfactory receptor 51B5	11121057	Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.

Q3U2S8	HVCN1_MOUSE	Voltage-gated hydrogen channel 1	16556803	A voltage sensor-domain protein is a voltage-gated proton channel.

O43066	PPK30_SCHPO	Serine/threonine-protein kinase ppk30	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O04922	GPX2_ARATH	Probable glutathione peroxidase 2	14617062	Glutathione peroxidase genes in Arabidopsis are ubiquitous and regulated by abiotic stresses through diverse signaling pathways.

Q9LRB0	LCBK1_ARATH	Sphingoid long-chain bases kinase 1	15695468	Phosphorylation of sphingoid long-chain bases in Arabidopsis: functional characterization and expression of the first sphingoid long-chain base Kinase gene in plants.

O15205	UBD_HUMAN	Ubiquitin D	19033385	The ubiquitin-like modifier FAT10 interacts with HDAC6 and localizes to aggresomes under proteasome inhibition.

Q13698	CAC1S_HUMAN	Voltage-dependent L-type calcium channel subunit alpha-1S	17418573	Hypokalaemic periodic paralysis due to the CACNA1S R1239H mutation in a large African family.

P51172	SCNND_HUMAN	Amiloride-sensitive sodium channel subunit delta	7499195	Molecular cloning and functional expression of a novel amiloride- sensitive Na+ channel.

Q9NRR4	RNC_HUMAN	Ribonuclease 3	10976766	A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening.

O88407	FAIM2_RAT	Fas apoptotic inhibitory molecule 2	9698393	Neural membrane protein 35 (NMP35): a novel member of a gene family which is highly expressed in the adult nervous system.

P08069	IGF1R_HUMAN	Insulin-like growth factor 1 receptor	8452530	Purified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinity.

Q8CF97	VCIP1_RAT	Deubiquitinating protein VCIP135	15037600	VCIP135 acts as a deubiquitinating enzyme during p97-p47-mediated reassembly of mitotic Golgi fragments.

P75906	PGAB_ECOLI	Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase	15090514	The pgaABCD locus of Escherichia coli promotes the synthesis of a polysaccharide adhesin required for biofilm formation.

Q9FPQ8	KNAT7_ARATH	Homeobox protein knotted-1-like 7	15980264	Identification of novel genes in Arabidopsis involved in secondary cell wall formation using expression profiling and reverse genetics.

P25109	ACHB_RAT	Acetylcholine receptor subunit beta	1702709	Primary structure and functional expression of the alpha-, beta-, gamma-, delta- and epsilon-subunits of the acetylcholine receptor from rat muscle.

Q39241	TRXH5_ARATH	Thioredoxin H5	7777559	Evidence for five divergent thioredoxin h sequences in Arabidopsis thaliana.

B7ZR65	SOX9A_XENLA	Transcription factor Sox-9-A	15464575	Early requirement of the transcriptional activator Sox9 for neural crest specification in Xenopus.

P53193	JAC1_YEAST	J-type co-chaperone JAC1, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P49677	IAA1_ARATH	Auxin-responsive protein IAA1	8278386	Early auxin-induced genes encode short-lived nuclear proteins.

Q9ZT63	MTP1_ARATH	Metal tolerance protein 1	11882948	Characterization of the ZAT1p zinc transporter from Arabidopsis thaliana in microbial model organisms and reconstituted proteoliposomes.

Q61214	DYR1A_MOUSE	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	15199138	Dyrk1A potentiates steroid hormone-induced transcription via the chromatin remodeling factor Arip4.

O43060	EIF3F_SCHPO	Eukaryotic translation initiation factor 3 subunit F	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P03881	YMRF1_YEAST	Uncharacterized mitochondrial protein RF1	9872396	The complete sequence of the mitochondrial genome of Saccharomyces cerevisiae.

Q02972	CADH8_ARATH	Cinnamyl alcohol dehydrogenase 8	17467016	Expression of cinnamyl alcohol dehydrogenases and their putative homologues during Arabidopsis thaliana growth and development: lessons for database annotations?

Q9Y7V1	YCHC_SCHPO	Uncharacterized protein C645.12c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9HFE1	FET4_SCHPO	Low-affinity iron/zinc ion transport protein fet4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P32961	NRL1_ARATH	Nitrilase 1	8022831	Differential regulation of an auxin-producing nitrilase gene family in Arabidopsis thaliana.

P04746	AMYP_HUMAN	Pancreatic alpha-amylase	6336237	A complementary DNA sequence that predicts a human pancreatic amylase primary structure consistent with the electrophoretic mobility of the common isozyme, Amy2 A.

P08107	HSP71_HUMAN	Heat shock 70 kDa protein 1A/1B	12853476	Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system.

Q14344	GNA13_HUMAN	Guanine nucleotide-binding protein subunit alpha-13	7791744	Expression of GTP-binding protein alpha subunits in human thymocytes.

P23508	CRCM_HUMAN	Colorectal mutant cancer protein	18591935	Mutated in colorectal cancer, a putative tumor suppressor for serrated colorectal cancer, selectively represses beta-catenin- dependent transcription.

P29353	SHC1_HUMAN	SHC-transforming protein 1	7537849	Phosphotyrosine-dependent interaction of SHC and insulin receptor substrate 1 with the NPEY motif of the insulin receptor via a novel non-SH2 domain.

Q9R0M4	PODXL_MOUSE	Podocalyxin	10591182	Identification of podocalyxin-like protein 1 as a novel cell surface marker for hemangioblasts in the murine aorta-gonad-mesonephros region.

P15515	HIS1_HUMAN	Histatin-1	8336540	Nucleotide sequence analysis of the human salivary protein genes HIS1 and HIS2, and evolution of the STATH/HIS gene family.

Q9UUM2	SWI1_SCHPO	Mating-type switching protein swi1	14560029	Swi1 prevents replication fork collapse and controls checkpoint kinase Cds1.

P20433	RPB4_YEAST	DNA-directed RNA polymerase II subunit RPB4	12857861	Rpb4p, a subunit of RNA polymerase II, mediates mRNA export during stress.

Q8VBT6	AB48R_MOUSE	Apolipoprotein B-100 receptor	12177162	The murine macrophage apoB-48 receptor gene (Apob-48r): homology to the human receptor.

P87145	VAC14_SCHPO	Protein VAC14 homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q6Q0C0	TRAF7_HUMAN	E3 ubiquitin-protein ligase TRAF7	14743216	A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.

Q9P7W8	RSC9_SCHPO	Chromatin structure-remodeling complex subunit rsc9	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9SSE7	AROD2_ARATH	Arogenate dehydratase/prephenate dehydratase 2, chloroplastic	19136569	Tyrosine and phenylalanine are synthesized within the plastids in Arabidopsis.

Q15233	NONO_HUMAN	Non-POU domain-containing octamer-binding protein	16148043	P54nrb forms a heterodimer with PSP1 that localizes to paraspeckles in an RNA-dependent manner.

Q12962	TAF10_HUMAN	Transcription initiation factor TFIID subunit 10	15099517	Gene-specific modulation of TAF10 function by SET9-mediated methylation.

Q99576	T22D3_HUMAN	TSC22 domain family protein 3	8982256	hDIP -- a potential transcriptional regulator related to murine TSC- 22 and Drosophila shortsighted (shs) -- is expressed in a large number of human tissues.

P51141	DVL1_MOUSE	Segment polarity protein dishevelled homolog DVL-1	15456783	Independent mutations in mouse Vangl2 that cause neural tube defects in looptail mice impair interaction with members of the Dishevelled family.

Q13541	4EBP1_HUMAN	Eukaryotic translation initiation factor 4E-binding protein 1	7935836	Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function.

P05813	CRBA1_HUMAN	Beta-crystallin A3	8999933	Sequence analysis of betaA3, betaB3, and betaA4 crystallins completes the identification of the major proteins in young human lens.

Q9JI70	MKKS_MOUSE	McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin	15772095	Mkks-null mice have a phenotype resembling Bardet-Biedl syndrome.

P70668	GUC2B_RAT	Guanylate cyclase activator 2B	8977100	Uroguanylin gene expression in the alimentary tract and extra- gastrointestinal tissues.

Q941Q3	C3H37_ARATH	Zinc finger CCCH domain-containing protein 37	11595801	HUA1, a regulator of stamen and carpel identities in Arabidopsis, codes for a nuclear RNA binding protein.

Q24533	DICH_DROME	SOX domain-containing protein dichaete	8951082	The Dichaete gene of Drosophila melanogaster encodes a SOX-domain protein required for embryonic segmentation.

O96006	ZBED1_HUMAN	Zinc finger BED domain-containing protein 1	9887332	A novel pseudoautosomal human gene encodes a putative protein similar to Ac-like transposases.

Q9V4A7	PLXB_DROME	Plexin-B	16672342	Drosophila Plexin B is a Sema-2a receptor required for axon guidance.

Q08726	GPN2_YEAST	GPN-loop GTPase 2 homolog	14562095	Global analysis of protein localization in budding yeast.

Q9Y6G9	DC1L1_HUMAN	Cytoplasmic dynein 1 light intermediate chain 1	19229290	Dynein light intermediate chain 1 is required for progress through the spindle assembly checkpoint.

Q6KFX9	RFNG_DANRE	Beta-1,3-N-acetylglucosaminyltransferase radical fringe	15659486	Wnt1 regulates neurogenesis and mediates lateral inhibition of boundary cell specification in the zebrafish hindbrain.

P17544	ATF7_HUMAN	Cyclic AMP-dependent transcription factor ATF-7	17264123	Sumoylation delays the ATF7 transcription factor subcellular localization and inhibits its transcriptional activity.

Q9C056	NKX62_HUMAN	Homeobox protein Nkx-6.2	11210186	Cloning, expression and chromosomal location of NKX6B to 10q26, a region frequently deleted in brain tumors.

P01160	ANF_HUMAN	Atrial natriuretic factor	6547996	mRNA sequence for human cardiodilatin-atrial natriuretic factor precursor and regulation of precursor mRNA in rat atria.

Q99965	ADAM2_HUMAN	Disintegrin and metalloproteinase domain-containing protein 2	9041139	Human fertilin beta: identification, characterization, and chromosomal mapping of an ADAM gene family member.

Q8TAE8	G45IP_HUMAN	Growth arrest and DNA damage-inducible proteins-interacting protein 1	12716909	CR6-interacting factor 1 interacts with Gadd45 family proteins and modulates the cell cycle.

Q32KD2	SETB1_DROME	Histone-lysine N-methyltransferase eggless	17164421	Histone methylation is required for oogenesis in Drosophila.

P52943	CRIP2_HUMAN	Cysteine-rich protein 2	8824798	Human ESP1/CRP2, a member of the LIM domain protein family: characterization of the cDNA and assignment of the gene locus to chromosome 14q32.3.

P30997	CTNA2_CHICK	Catenin alpha-2	1638632	Identification of a neural alpha-catenin as a key regulator of cadherin function and multicellular organization.

Q23794	HMGA1_CHITE	High mobility group protein I	7806532	Insect proteins homologous to mammalian high mobility group proteins I/Y (HMG I/Y). Characterization and binding to linear and four-way junction DNA.

P16151	ERD1_YEAST	Protein ERD1	2178921	ERD1, a yeast gene required for the retention of luminal endoplasmic reticulum proteins, affects glycoprotein processing in the Golgi apparatus.

Q01955	CO4A3_HUMAN	Collagen alpha-3(IV) chain	12682293	Human tumstatin and human endostatin exhibit distinct antiangiogenic activities mediated by alpha v beta 3 and alpha 5 beta 1 integrins.

Q08ET2	SIG14_HUMAN	Sialic acid-binding Ig-like lectin 14	17012248	Discovery of Siglec-14, a novel sialic acid receptor undergoing concerted evolution with Siglec-5 in primates.

Q54XS3	GDT1_DICDI	Probable inactive serine/threonine-protein kinase gdt1	10793140	gdt1, a new signal transduction component for negative regulation of the growth-differentiation transition.

P06312	KV401_HUMAN	Ig kappa chain V-IV region	2997712	Subgroup IV of human immunoglobulin K light chains is encoded by a single germline gene.

Q9CAF6	GYRA_ARATH	Probable DNA gyrase subunit A, chloroplastic/mitochondrial	15136745	Arabidopsis thaliana DNA gyrase is targeted to chloroplasts and mitochondria.

O42862	YFC2_SCHPO	Uncharacterized membrane protein C25A8.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9VZJ6	GR64D_DROME	Putative gustatory receptor 64d	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

Q9SWE5	HAL3A_ARATH	Phosphopantothenoylcysteine decarboxylase	10652125	Arabidopsis thaliana AtHAL3: a flavoprotein related to salt and osmotic tolerance and plant growth.

P40583	YPS6_YEAST	Aspartic proteinase yapsin-6	10383953	Amino acid residues in the omega-minus region participate in cellular localization of yeast glycosylphosphatidylinositol-attached proteins.

P26309	CDC20_YEAST	APC/C activator protein CDC20	11566880	Yeast Hct1 recognizes the mitotic cyclin Clb2 and other substrates of the ubiquitin ligase APC.

P30554	MAS_MOUSE	Proto-oncogene Mas	12829792	Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas.

Q969S8	HDA10_HUMAN	Histone deacetylase 10	11726666	Molecular cloning and characterization of a novel histone deacetylase HDAC10.

O15111	IKKA_HUMAN	Inhibitor of nuclear factor kappa-B kinase subunit alpha	9252186	A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB.

Q7Z4N2	TRPM1_HUMAN	Transient receptor potential cation channel subfamily M member 1	9806836	Chromosomal localization and genomic characterization of the mouse melastatin gene (Mlsn1).

P38627	URA8_YEAST	CTP synthase 2	9668079	Effect of CTP synthetase regulation by CTP on phospholipid synthesis in Saccharomyces cerevisiae.

P81921	OR47A_DROME	Odorant receptor 47a	10089887	A spatial map of olfactory receptor expression in the Drosophila antenna.

Q9UBM4	OPT_HUMAN	Opticin	10636917	Identification in vitreous and molecular cloning of opticin, a novel member of the family of leucine-rich repeat proteins of the extracellular matrix.

Q07021	C1QBP_HUMAN	Complement component 1 Q subcomponent-binding protein, mitochondrial	8195709	Isolation, cDNA cloning, and overexpression of a 33-kD cell surface glycoprotein that binds to the globular 'heads' of C1q.

Q9C104	GDE1_SCHPO	Glycerophosphodiester phosphodiesterase gde1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O04196	ISOA1_ARATH	Isoamylase 1, chloroplastic	18815382	Further evidence for the mandatory nature of polysaccharide debranching for the aggregation of semicrystalline starch and for overlapping functions of debranching enzymes in Arabidopsis leaves.

P53794	SC5A3_HUMAN	Sodium/myo-inositol cotransporter	7789985	The human osmoregulatory Na+/myo-inositol cotransporter gene (SLC5A3): molecular cloning and localization to chromosome 21.

P0AFU8	RISA_ECOLI	Riboflavin synthase alpha chain	9022701	Cloning, sequencing, mapping and hyperexpression of the ribC gene coding for riboflavin synthase of Escherichia coli.

P28040	DPOA_SCHPO	DNA polymerase alpha catalytic subunit	8423854	DNA polymerase-alpha is essential for mating-type switching in fission yeast.

O95834	EMAL2_HUMAN	Echinoderm microtubule-associated protein-like 2	10521658	Sequence and expression patterns of a human EMAP-related protein-2 (HuEMAP-2).

Q3YBM2	T176B_HUMAN	Transmembrane protein 176B	9922225	Isolation of a gene product expressed by a subpopulation of human lung fibroblasts by differential display.

P46958	IDS2_YEAST	IME2-dependent-signaling protein	7565676	Stimulation of later functions of the yeast meiotic protein kinase Ime2p by the IDS2 gene product.

O14978	ZN263_HUMAN	Zinc finger protein 263	9256059	Isolation of a cDNA encoding a widely expressed novel zinc finger protein with the LeR and KRAB-A domains.

Q9UT20	YFY8_SCHPO	Uncharacterized protein C9.08c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O24606	EIN3_ARATH	Protein ETHYLENE INSENSITIVE 3	9851977	Nuclear events in ethylene signaling: a transcriptional cascade mediated by ETHYLENE-INSENSITIVE3 and ETHYLENE-RESPONSE-FACTOR1.

Q9WVC1	SLIT2_RAT	Slit homolog 2 protein	10364234	Mammalian homologues of the Drosophila slit protein are ligands of the heparan sulfate proteoglycan glypican-1 in brain.

Q53QZ3	RHG15_HUMAN	Rho GTPase-activating protein 15	12650940	ArhGAP15, a novel human RacGAP protein with GTPase binding property.

Q9VA70	NCASE_DROME	Neutral ceramidase	12637747	Modulating sphingolipid biosynthetic pathway rescues photoreceptor degeneration.

A2AP18	PLCH2_MOUSE	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta-2	15899900	A novel phospholipase C, PLC(eta)2, is a neuron-specific isozyme.

P29274	AA2AR_HUMAN	Adenosine receptor A2a	16339847	The ubiquitin-specific protease Usp4 regulates the cell surface level of the A2A receptor.

Q91V98	CD248_MOUSE	Endosialin	11489895	Molecular characterization of the mouse Tem1/endosialin gene regulated by cell density in vitro and expressed in normal tissues in vivo.

Q8CCE9	E4F1_MOUSE	Transcription factor E4F1	15226446	The E4F protein is required for mitotic progression during embryonic cell cycles.

Q14258	TRI25_HUMAN	E3 ubiquitin/ISG15 ligase TRIM25	8248217	Genomic binding-site cloning reveals an estrogen-responsive gene that encodes a RING finger protein.

Q8GT74	NIP2_ARATH	NEP1-interacting protein 2	18567673	Intraplastidial trafficking of a phage-type RNA polymerase is mediated by a thylakoid RING-H2 protein.

Q12338	RNH2C_YEAST	Ribonuclease H2 subunit C	14562095	Global analysis of protein localization in budding yeast.

P35999	PMIP_YEAST	Mitochondrial intermediate peptidase	10332043	Mitochondrial intermediate peptidase and the yeast frataxin homolog together maintain mitochondrial iron homeostasis in Saccharomyces cerevisiae.

Q84VG7	C3H27_ARATH	Zinc finger CCCH domain-containing protein 27	16291783	FRIGIDA-ESSENTIAL 1 interacts genetically with FRIGIDA and FRIGIDA- LIKE 1 to promote the winter-annual habit of Arabidopsis thaliana.

Q61409	PDE3B_MOUSE	cGMP-inhibited 3',5'-cyclic phosphodiesterase B	10454575	Insulin-induced phosphorylation and activation of cyclic nucleotide phosphodiesterase 3B by the serine-threonine kinase Akt.

P03956	MMP1_HUMAN	Interstitial collagenase	2167156	Cloning and characterization of human tumor cell interstitial collagenase.

Q9P2D0	IBTK_HUMAN	Inhibitor of Bruton tyrosine kinase	11577348	Direct inhibition of Bruton's tyrosine kinase by IBtk, a Btk-binding protein.

Q8JGR7	INT7_DANRE	Integrator complex subunit 7	15716491	Identification of zebrafish insertional mutants with defects in visual system development and function.

P38418	LOX2_ARATH	Lipoxygenase 2, chloroplastic	14729914	In-depth analysis of the thylakoid membrane proteome of Arabidopsis thaliana chloroplasts: new proteins, new functions, and a plastid proteome database.

O14744	ANM5_HUMAN	Protein arginine N-methyltransferase 5	18404153	The histone-binding protein COPR5 is required for nuclear functions of the protein arginine methyltransferase PRMT5.

Q13291	SLAF1_HUMAN	Signaling lymphocytic activation molecule	7617038	A novel receptor involved in T-cell activation.

P21675	TAF1_HUMAN	Transcription initiation factor TFIID subunit 1	9660973	Functional analysis of the human TAFII250 N-terminal kinase domain.

Q9NZI8	IF2B1_HUMAN	Insulin-like growth factor 2 mRNA-binding protein 1	17101699	ZBP1 regulates mRNA stability during cellular stress.

P48051	IRK6_HUMAN	G protein-activated inward rectifier potassium channel 2	7796919	Characterization and variation of a human inwardly-rectifying-K- channel gene (KCNJ6): a putative ATP-sensitive K-channel subunit.

P09874	PARP1_HUMAN	Poly [ADP-ribose] polymerase 1	18172500	Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins.

P53849	GIS2_YEAST	Zinc finger protein GIS2	14562095	Global analysis of protein localization in budding yeast.

O35346	FAK1_RAT	Focal adhesion kinase 1	8738136	Cloning of focal adhesion kinase, pp125FAK, from rat brain reveals multiple transcripts with different patterns of expression.

O94387	YGSA_SCHPO	Uncharacterized ATP-dependent helicase C29A10.10c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O33245	PSB_MYCTU	Proteasome subunit beta	16468985	Mycobacterium tuberculosis prcBA genes encode a gated proteasome with broad oligopeptide specificity.

Q14493	SLBP_HUMAN	Histone RNA hairpin-binding protein	16912046	Characterization of 3'hExo, a 3' exonuclease specifically interacting with the 3' end of histone mRNA.

Q9BZP6	CHIA_HUMAN	Acidic mammalian chitinase	18824549	Acidic mammalian chitinase is secreted via an ADAM17/epidermal growth factor receptor-dependent pathway and stimulates chemokine production by pulmonary epithelial cells.

Q38898	AKT2_ARATH	Potassium channel AKT2/3	11181729	The AKT3 potassium channel protein interacts with the AtPP2CA protein phosphatase 2C.

P53913	FYV6_YEAST	Protein FYV6	12399380	A genomics-based screen for yeast mutants with an altered recombination/end-joining repair ratio.

Q92851	CASPA_HUMAN	Caspase-10	10412980	Inherited human caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II.

P38777	FSH1_YEAST	Family of serine hydrolases 1	14562095	Global analysis of protein localization in budding yeast.

P68402	PA1B2_HUMAN	Platelet-activating factor acetylhydrolase IB subunit beta	9144386	Differential tissue distribution of the beta- and gamma-subunits of human cytosolic platelet-activating factor acetylhydrolase (isoform I).

Q7Z7C8	TAF8_HUMAN	Transcription initiation factor TFIID subunit 8	15870280	The nuclear import of TAF10 is regulated by one of its three histone fold domain-containing interaction partners.

P53258	GYP2_YEAST	GTPase-activating protein GYP2	15574876	Synthetic genetic array analysis of the PtdIns 4-kinase Pik1p identifies components in a Golgi-specific Ypt31/rab-GTPase signaling pathway.

Q944G9	ALFC2_ARATH	Probable fructose-bisphosphate aldolase 2, chloroplastic	16461379	Protein profiling of plastoglobules in chloroplasts and chromoplasts. A surprising site for differential accumulation of metabolic enzymes.

Q92766	RREB1_HUMAN	Ras-responsive element-binding protein 1	9305772	A novel zinc finger protein, Finb, is a transcriptional activator and localized in nuclear bodies.

Q92838	EDA_HUMAN	Ectodysplasin-A	9736768	The anhidrotic ectodermal dysplasia gene (EDA) undergoes alternative splicing and encodes ectodysplasin-A with deletion mutations in collagenous repeats.

P04271	S100B_HUMAN	Protein S100-B	9519411	A novel calcium-sensitive switch revealed by the structure of human S100B in the calcium-bound form.

O14617	AP3D1_HUMAN	AP-3 complex subunit delta-1	9151686	Characterization of the adaptor-related protein complex, AP-3.

P48645	NMU_HUMAN	Neuromedin-U	7619205	Cloning and characterization of the cDNA encoding the human neuromedin U (NmU) precursor: NmU expression in the human gastrointestinal tract.

Q09892	HOG1_SCHPO	Mitogen-activated protein kinase sty1	16141205	The glycolytic metabolite methylglyoxal activates Pap1 and Sty1 stress responses in Schizosaccharomyces pombe.

Q923V8	SEP15_RAT	15 kDa selenoprotein	11278576	Association between the 15-kDa selenoprotein and UDP- glucose:glycoprotein glucosyltransferase in the endoplasmic reticulum of mammalian cells.

O75309	CAD16_HUMAN	Cadherin-16	9721215	cDNA cloning and chromosomal localization of the human and mouse isoforms of Ksp-cadherin.

Q9UI32	GLSL_HUMAN	Glutaminase liver isoform, mitochondrial	10620514	Molecular cloning, sequencing and expression studies of the human breast cancer cell glutaminase.

P37202	DIS3_SCHPO	Exosome complex exonuclease dis3	8896453	Dis3, implicated in mitotic control, binds directly to Ran and enhances the GEF activity of RCC1.

P0A794	PDXJ_ECOLI	Pyridoxine 5'-phosphate synthase	1537799	Locating essential Escherichia coli genes by using mini-Tn10 transposons: the pdxJ operon.

Q9QXT8	CSEN_MOUSE	Calsenilin	11161465	Mouse DREAM/calsenilin/KChIP3: gene structure, coding potential and expression.

P14743	NMT_YEAST	Glycylpeptide N-tetradecanoyltransferase	8955162	Biochemical studies of Saccharomyces cerevisiae myristoyl-coenzyme A:protein N-myristoyltransferase mutants.

Q9SXZ2	FT_ARATH	Protein FLOWERING LOCUS T	16099980	Integration of spatial and temporal information during floral induction in Arabidopsis.

Q9UQL6	HDAC5_HUMAN	Histone deacetylase 5	10898795	BCoR, a novel corepressor involved in BCL-6 repression.

P46961	GPI2_YEAST	Phosphatidylinositol N-acetylglucosaminyltransferase GPI2 subunit	7768896	Temperature-sensitive yeast GPI anchoring mutants gpi2 and gpi3 are defective in the synthesis of N-acetylglucosaminyl phosphatidylinositol. Cloning of the GPI2 gene.

P62952	BLCAP_HUMAN	Bladder cancer-associated protein	17031575	Overexpression of BLCAP induces S phase arrest and apoptosis independent of p53 and NF-kappaB in human tongue carcinoma:BLCAP overexpression induces S phase arrest and apoptosis.

Q9UW14	PACC_CANAL	pH-response transcription factor pacC/RIM101	12912891	Diverged binding specificity of Rim101p, the Candida albicans ortholog of PacC.

Q60963	PAFA_MOUSE	Platelet-activating factor acetylhydrolase	7592717	Plasma platelet-activating factor acetylhydrolase is a secreted phospholipase A2 with a catalytic triad.

P49446	PTPRE_MOUSE	Receptor-type tyrosine-protein phosphatase epsilon	19508371	Protein tyrosine phosphatase epsilon is a negative regulator of FcepsilonRI-mediated mast cell responses.

Q16559	TAL2_HUMAN	T-cell acute lymphocytic leukemia protein 2	1763056	TAL2, a helix-loop-helix gene activated by the (7;9)(q34;q32) translocation in human T-cell leukemia.

Q9ES83	POPD1_MOUSE	Blood vessel epicardial substance	10882522	Isolation and characterization of the novel popeye gene family expressed in skeletal muscle and heart.

Q9UBL3	ASH2L_HUMAN	Set1/Ash2 histone methyltransferase complex subunit ASH2	11466562	ASH2L: alternative splicing and downregulation during induced megakaryocytic differentiation of multipotential leukemia cell lines.

P11142	HSP7C_HUMAN	Heat shock cognate 71 kDa protein	8713105	Identification of the 70kD heat shock cognate protein (Hsc70) and alpha-actinin-1 as novel phosphotyrosine-containing proteins in T lymphocytes.

Q32MW3	ACO10_MOUSE	Acyl-coenzyme A thioesterase 10, mitochondrial	10383425	Molecular cloning and characterization of MT-ACT48, a novel mitochondrial acyl-CoA thioesterase.

P32849	RAD5_YEAST	DNA repair protein RAD5	10880451	Two RING finger proteins mediate cooperation between ubiquitin- conjugating enzymes in DNA repair.

P38824	COX23_YEAST	Cytochrome c oxidase-assembly factor COX23, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

Q08683	APC5_YEAST	Anaphase-promoting complex subunit 5	12609981	Mnd2 and Swm1 are core subunits of the Saccharomyces cerevisiae anaphase-promoting complex.

O94392	YLV1_SCHPO	Uncharacterized transcriptional regulatory protein C2H10.01	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P15205	MAP1B_RAT	Microtubule-associated protein 1B	9260743	Differential regulation of microtubule-associated protein 1B (MAP1B) in rat CNS and PNS during development.

Q01196	RUNX1_HUMAN	Runt-related transcription factor 1	12217689	The RUNX1 Runt domain at 1.25A resolution: a structural switch and specifically bound chloride ions modulate DNA binding.

P78794	CWC15_SCHPO	Pre-mRNA-splicing factor cwc15	11884590	Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

Q01082	SPTB2_HUMAN	Spectrin beta chain, brain 1	1527002	Characterization of human brain cDNA encoding the general isoform of beta-spectrin.

Q8TAI7	REBL1_HUMAN	GTPase RhebL1	16328882	Identification and characterization of RHEBL1, a novel member of Ras family, which activates transcriptional activities of NF-kappa B.

Q03468	ERCC6_HUMAN	DNA excision repair protein ERCC-6	16916636	Cockayne syndrome A and B proteins differentially regulate recruitment of chromatin remodeling and repair factors to stalled RNA polymerase II in vivo.

P85071	GRAH1_RANGR	Grahamin-1	16487561	Two antimicrobial peptides from skin secretions of Rana grahami.

Q9DGE2	MK14A_DANRE	Mitogen-activated protein kinase 14A	10995439	Asymmetric p38 activation in zebrafish: its possible role in symmetric and synchronous cleavage.

P36915	GNL1_HUMAN	Guanine nucleotide-binding protein-like 1	17525332	ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

Q08050	FOXM1_HUMAN	Forkhead box protein M1	9242644	Molecular analysis of a novel winged helix protein, WIN. Expression pattern, DNA binding property, and alternative splicing within the DNA binding domain.

Q12789	TF3C1_HUMAN	General transcription factor 3C polypeptide 1	8164661	Cloning and characterization of an evolutionarily divergent DNA- binding subunit of mammalian TFIIIC.

Q86I79	PSCA_DICDI	Penicillin-sensitive carboxypeptidase A	12843630	Identification of a penicillin-sensitive carboxypeptidase in the cellular slime mold Dictyostelium discoideum.

Q99MJ6	NHRF4_MOUSE	Na(+)/H(+) exchange regulatory cofactor NHE-RF4	11099500	Interaction of the type IIa Na/Pi-cotransporter with PDZ proteins.

Q5PYH7	DLG2_DANRE	Disks large homolog 2	15660367	Characterization of zebrafish PSD-95 gene family members.

Q12144	YL064_YEAST	UPF0121 membrane protein YLR064W	14562095	Global analysis of protein localization in budding yeast.

Q6X0I2	VGR_SOLIN	Vitellogenin receptor	15056367	cDNA cloning and transcriptional regulation of the vitellogenin receptor from the imported fire ant, Solenopsis invicta Buren (Hymenoptera: Formicidae).

Q96FV9	THOC1_HUMAN	THO complex subunit 1	15998806	Recruitment of the human TREX complex to mRNA during splicing.

Q9ESF1	OTOF_MOUSE	Otoferlin	17055430	Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse.

Q60736	ZP3R_MOUSE	Zona pellucida sperm-binding protein 3 receptor	11133656	Mouse sperm protein sp56 is a component of the acrosomal matrix.

Q9FML2	HDA6_ARATH	Histone deacetylase 6	16648464	Erasure of histone acetylation by Arabidopsis HDA6 mediates large- scale gene silencing in nucleolar dominance.

Q9SX85	SEC3A_ARATH	Exocyst complex component SEC3A	18492870	An exocyst complex functions in plant cell growth in Arabidopsis and tobacco.

Q9LTB8	CNBL9_ARATH	Calcineurin B-like protein 9	17922773	Two calcineurin B-like calcium sensors, interacting with protein kinase CIPK23, regulate leaf transpiration and root potassium uptake in Arabidopsis.

O94688	APC15_SCHPO	Anaphase-promoting complex subunit 15	12477395	Proteomics analysis identifies new components of the fission and budding yeast anaphase-promoting complexes.

Q04759	KPCT_HUMAN	Protein kinase C theta type	10636891	Inhibition of the c-Jun N-terminal kinase/AP-1 and NF-kappaB pathways by PICOT, a novel protein kinase C-interacting protein with a thioredoxin homology domain.

Q19626	VATB_CAEEL	Probable V-type proton ATPase subunit B	16005300	The vacuolar H+ -ATPase mediates intracellular acidification required for neurodegeneration in C. elegans.

Q9XIE2	AB36G_ARATH	ABC transporter G family member 36	16732289	Conserved requirement for a plant host cell protein in powdery mildew pathogenesis.

Q02241	KIF23_HUMAN	Kinesin-like protein KIF23	1406973	A plus-end-directed motor enzyme that moves antiparallel microtubules in vitro localizes to the interzone of mitotic spindles.

P10634	CP2DQ_RAT	Cytochrome P450 2D26	2107330	The rat P450 IID subfamily: complete sequences of four closely linked genes and evidence that gene conversions maintained sequence homogeneity at the heme-binding region of the cytochrome P450 active site.

O49505	NCED2_ARATH	9-cis-epoxycarotenoid dioxygenase NCED2, chloroplastic	11532178	Regulation of drought tolerance by gene manipulation of 9-cis- epoxycarotenoid dioxygenase, a key enzyme in abscisic acid biosynthesis in Arabidopsis.

Q9GNK5	PGPLC_DROME	Peptidoglycan-recognition protein LC	11106397	A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster.

Q9UJ98	STAG3_HUMAN	Cohesin subunit SA-3	10698974	STAG3, a novel gene encoding a protein involved in meiotic chromosome pairing and location of STAG3-related genes flanking the Williams- Beuren syndrome deletion.

Q8NFJ5	RAI3_HUMAN	Retinoic acid-induced protein 3	9857033	Molecular cloning and characterization of a novel retinoic acid- inducible gene that encodes a putative G protein-coupled receptor.

Q8CJ40	CROCC_MOUSE	Rootletin	16339073	Rootletin interacts with C-Nap1 and may function as a physical linker between the pair of centrioles/basal bodies in cells.

P15509	CSF2R_HUMAN	Granulocyte-macrophage colony-stimulating factor receptor subunit alpha	2555171	Expression cloning of a receptor for human granulocyte-macrophage colony-stimulating factor.

O43889	CREB3_HUMAN	Cyclic AMP-responsive element-binding protein 3	10629049	Mutations in host cell factor 1 separate its role in cell proliferation from recruitment of VP16 and LZIP.

Q9FFI0	HDG9_ARATH	Homeobox-leucine zipper protein HDG9	16778018	Characterization of the class IV homeodomain-leucine zipper gene family in Arabidopsis.

Q08975	THI21_YEAST	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI21	10383756	Genetic redundancy and gene fusion in the genome of the Baker's yeast Saccharomyces cerevisiae: functional characterization of a three- member gene family involved in the thiamine biosynthetic pathway.

Q9NRR3	C42S2_HUMAN	CDC42 small effector protein 2	10816584	SPECs, small binding proteins for Cdc42.

Q9V574	L2K1_DROME	Protein lethal(2)k10201	8985246	The Drosophila protein Wunen repels migrating germ cells.

P25105	PTAFR_HUMAN	Platelet-activating factor receptor	1374385	The human leukocyte platelet-activating factor receptor. cDNA cloning, cell surface expression, and construction of a novel epitope- bearing analog.

P81877	SSBP2_HUMAN	Single-stranded DNA-binding protein 2	12079286	A novel, evolutionarily conserved gene family with putative sequence- specific single-stranded DNA-binding activity.

P60570	PANX1_RAT	Pannexin-1	14597722	Pannexins, a family of gap junction proteins expressed in brain.

Q9BXN1	ASPN_HUMAN	Asporin	19589127	Asporin competes with decorin for collagen binding, binds calcium and promotes osteoblast collagen mineralization.

P16235	LSHR_RAT	Lutropin-choriogonadotropic hormone receptor	2174034	Intronic nature of the rat luteinizing hormone receptor gene defines a soluble receptor subspecies with hormone binding activity.

Q8MJV3	NPBW1_BOVIN	Neuropeptides B/W receptor type 1	12118011	Identification of a neuropeptide modified with bromine as an endogenous ligand for GPR7.

Q13564	ULA1_HUMAN	NEDD8-activating enzyme E1 regulatory subunit	12740388	Conservation in the mechanism of Nedd8 activation by the human AppBp1-Uba3 heterodimer.

Q8ID39	Y13P2_PLAF7	Uncharacterized protein MAL13P1.336	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

Q96H96	COQ2_HUMAN	Para-hydroxybenzoate--polyprenyltransferase, mitochondrial	15153069	Isolation and functional expression of human COQ2, a gene encoding a polyprenyl transferase involved in the synthesis of CoQ2.

O43747	AP1G1_HUMAN	AP-1 complex subunit gamma-1	9653655	Cloning, expression pattern, and chromosomal assignment to 16q23 of the human gamma-adaptin gene (ADTG).

P01814	HV201_HUMAN	Ig heavy chain V-II region OU	4742735	Complete amino acid sequence of the Mu heavy chain of a human IgM immunoglobulin.

Q9NQ50	RM40_HUMAN	39S ribosomal protein L40, mitochondrial	9790763	Isolation and characterization of a human gene containing a nuclear localization signal from the critical region for velo-cardio-facial syndrome on 22q11.

Q8K3K4	SPB10_RAT	Serpin B10	11986314	Identification and characterization of a novel rat ov-serpin family member, trespin.

Q13432	U119A_HUMAN	Protein unc-119 homolog A	10329014	Characterization of the gene for HRG4 (UNC119), a novel photoreceptor synaptic protein homologous to unc-119.

P02751	FINC_HUMAN	Fibronectin	16336961	A novel role for fibronectin type I domain in the regulation of human hematopoietic cell adhesiveness through binding to follistatin domains of FLRG and follistatin.

P40482	SEC24_YEAST	Protein transport protein SEC24	9325247	COPII subunit interactions in the assembly of the vesicle coat.

Q9JIP3	I17RB_MOUSE	Interleukin-17 receptor B	10815801	Evi27 encodes a novel membrane protein with homology to the IL17 receptor.

Q07950	YEH2_YEAST	Sterol esterase 2	15632184	YEH2/YLR020c encodes a novel steryl ester hydrolase of the yeast Saccharomyces cerevisiae.

P32297	ACHA3_HUMAN	Neuronal acetylcholine receptor subunit alpha-3	8906617	Comparative structure of human neuronal alpha 2-alpha 7 and beta 2- beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits.

Q02825	SEN54_YEAST	tRNA-splicing endonuclease subunit SEN54	12925762	Possibility of cytoplasmic pre-tRNA splicing: the yeast tRNA splicing endonuclease mainly localizes on the mitochondria.

P49028	MGN_DROME	Protein mago nashi	12730685	A novel mode of RBD-protein recognition in the Y14-Mago complex.

P38336	POP4_YEAST	RNases MRP/P 32.9 kDa subunit	9620854	Purification and characterization of the nuclear RNase P holoenzyme complex reveals extensive subunit overlap with RNase MRP.

Q91926	VENT1_XENLA	Homeobox protein vent1	9502725	Requirement for Xvent-1 and Xvent-2 gene function in dorsoventral patterning of Xenopus mesoderm.

Q9USV7	CTR6_SCHPO	Copper transport protein ctr6	12244050	Ctr6, a vacuolar membrane copper transporter in Schizosaccharomyces pombe.

O00287	RFXAP_HUMAN	Regulatory factor X-associated protein	9118943	RFXAP, a novel subunit of the RFX DNA binding complex is mutated in MHC class II deficiency.

Q7BVH7	SSEB_SALTY	Secreted effector protein sseB	9786193	Genes encoding putative effector proteins of the type III secretion system of Salmonella pathogenicity island 2 are required for bacterial virulence and proliferation in macrophages.

Q99442	SEC62_HUMAN	Translocation protein SEC62	9020021	Identification of a human cDNA homologue to the Drosophila translocation protein 1 (Dtrp-1).

Q582G4	ANM7_TRYBB	Protein arginine N-methyltransferase 7	19254949	A type III protein arginine methyltransferase from the protozoan parasite Trypanosoma brucei.

Q9TVY6	SPE9_CAEEL	Sperm transmembrane protein 9	15282160	Functional domains and temperature-sensitive mutations in SPE-9, an EGF repeat-containing protein required for fertility in Caenorhabditis elegans.

Q9JK11	RTN4_RAT	Reticulon-4	10667796	Nogo-A is a myelin-associated neurite outgrowth inhibitor and an antigen for monoclonal antibody IN-1.

Q92888	ARHG1_HUMAN	Rho guanine nucleotide exchange factor 1	8810315	Identification of a novel guanine nucleotide exchange factor for the rho GTPase.

Q9UBF9	MYOTI_HUMAN	Myotilin	11038172	Indications for a novel muscular dystrophy pathway: gamma-filamin, the muscle-specific filamin isoform, interacts with myotilin.

P47736	RPGP1_HUMAN	Rap1 GTPase-activating protein 1	1904317	Molecular cloning of a GTPase activating protein specific for the Krev-1 protein p21rap1.

Q15276	RABE1_HUMAN	Rab GTPase-binding effector protein 1	15378032	Structural basis of Rab5-Rabaptin5 interaction in endocytosis.

O43687	AKA7A_HUMAN	A-kinase anchor protein 7 isoforms alpha and beta	9545239	A novel lipid-anchored A-kinase anchoring protein facilitates cAMP- responsive membrane events.

Q95ZN4	NLP33_CAEEL	Neuropeptide-like protein 33	15048112	TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM.

P40123	CAP2_HUMAN	Adenylyl cyclase-associated protein 2	7962207	Comparison of human CAP and CAP2, homologs of the yeast adenylyl cyclase-associated proteins.

P31119	AAS_ECOLI	Bifunctional protein aas	1649829	Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.

Q8N5A5	ZGPAT_HUMAN	Zinc finger CCCH-type with G patch domain-containing protein	19644445	ZIP: a novel transcription repressor, represses EGFR oncogene and suppresses breast carcinogenesis.

P0AEU7	SKP_ECOLI	Chaperone protein skp	12509434	Folding and insertion of the outer membrane protein OmpA is assisted by the chaperone Skp and by lipopolysaccharide.

P62280	RS11_HUMAN	40S ribosomal protein S11	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

Q61699	HS105_MOUSE	Heat shock protein 105 kDa	14644449	Hsp105 but not Hsp70 family proteins suppress the aggregation of heat-denatured protein in the presence of ADP.

Q14353	GAMT_HUMAN	Guanidinoacetate N-methyltransferase	9325156	The human guanidinoacetate methyltransferase (GAMT) gene maps to a syntenic region on 19p13.3, homologous to band C of mouse chromosome 10, but GAMT is not mutated in jittery mice.

Q91ZA3	PCCA_MOUSE	Propionyl-CoA carboxylase alpha chain, mitochondrial	11461925	Fatal propionic acidemia in mice lacking propionyl-CoA carboxylase and its rescue by postnatal, liver-specific supplementation via a transgene.

Q9M099	SCP24_ARATH	Serine carboxypeptidase 24	16123046	Arabidopsis BRS1 is a secreted and active serine carboxypeptidase.

Q658P3	STEA3_HUMAN	Metalloreductase STEAP3	15319436	TSAP6 facilitates the secretion of translationally controlled tumor protein/histamine-releasing factor via a nonclassical pathway.

B1AZP2	DLGP4_MOUSE	Disks large-associated protein 4	15024750	Differential mRNA expression and protein localization of the SAP90/PSD-95-associated proteins (SAPAPs) in the nervous system of the mouse.

P40056	GET2_YEAST	Golgi to ER traffic protein 2	16269340	Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile.

P14540	ALF_YEAST	Fructose-bisphosphate aldolase	2647491	Molecular cloning, primary structure and disruption of the structural gene of aldolase from Saccharomyces cerevisiae.

Q6P2C8	MED27_HUMAN	Mediator of RNA polymerase II transcription subunit 27	10882111	The USA-derived transcriptional coactivator PC2 is a submodule of TRAP/SMCC and acts synergistically with other PCs.

P15328	FOLR1_HUMAN	Folate receptor alpha	1840502	Cloning of a tumor-associated antigen: MOv18 and MOv19 antibodies recognize a folate-binding protein.

P22216	RAD53_YEAST	Serine/threonine-protein kinase RAD53	8355715	SPK1 is an essential S-phase-specific gene of Saccharomyces cerevisiae that encodes a nuclear serine/threonine/tyrosine kinase.

P07670	PYRD_DICDI	Dihydroorotate dehydrogenase	2996629	Sequence analysis of a Dictyostelium discoideum gene coding for an active dihydroorotate dehydrogenase in yeast.

Q5G872	SCUB2_DANRE	Signal peptide, CUB and EGF-like domain-containing protein 2	15753045	The zebrafish-secreted matrix protein You/Scube2 is implicated in long-range regulation of hedgehog signaling.

Q6TEK4	VKOR1_RAT	Vitamin K epoxide reductase complex subunit 1	15640149	Engineering of a recombinant vitamin K-dependent (gamma)- carboxylation system with enhanced (gamma)-carboxyglutamic acid forming capacity: evidence for a functional CxxC redox center in the system.

P08593	MSS18_YEAST	Protein MSS18	2842150	MSS18, a yeast nuclear gene involved in the splicing of intron aI5 beta of the mitochondrial cox1 transcript.

Q9UQF2	JIP1_HUMAN	C-Jun-amino-terminal kinase-interacting protein 1	11238452	Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules.

Q24318	TFDP_DROME	Transcription factor Dp	8022787	DNA-binding and trans-activation properties of Drosophila E2F and DP proteins.

P17157	PHO85_YEAST	Cyclin-dependent protein kinase PHO85	7973730	Cell cycle control by a complex of the cyclin HCS26 (PCL1) and the kinase PHO85.

P17157	PHO85_YEAST	Cyclin-dependent protein kinase PHO85	12101234	Regulation of the transcription factor Gcn4 by Pho85 cyclin PCL5.

O15392	BIRC5_HUMAN	Baculoviral IAP repeat-containing protein 5	16322459	Chromosome alignment and segregation regulated by ubiquitination of survivin.

Q12517	DCP1_YEAST	mRNA-decapping enzyme subunit 1	11139489	Two related proteins, Edc1p and Edc2p, stimulate mRNA decapping in Saccharomyces cerevisiae.

P38590	MSG5_YEAST	Tyrosine-protein phosphatase MSG5	8306972	MSG5, a novel protein phosphatase promotes adaptation to pheromone response in S. cerevisiae.

Q9NZC9	SMAL1_HUMAN	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1	18974355	HARP is an ATP-driven annealing helicase.

P39276	YJDL_ECOLI	Probable dipeptide and tripeptide permease YjdL	19703419	Ligand binding analyses of the putative peptide transporter YjdL from E. coli display a significant selectivity towards dipeptides.

Q54QG0	PGFB_DICDI	Bifunctional glycosyltransferase pgtA	11423539	A non-Golgi alpha 1,2-fucosyltransferase that modifies Skp1 in the cytoplasm of Dictyostelium.

Q9UR17	VTC1_SCHPO	Vacuolar transporter chaperone 1	10628977	Isolation and characterization of Nrf1p, a novel negative regulator of the Cdc42p GTPase in Schizosaccharomyces pombe.

Q10271	ARB2_SCHPO	Argonaute-binding protein 2	17310250	Two different Argonaute complexes are required for siRNA generation and heterochromatin assembly in fission yeast.

P19838	NFKB1_HUMAN	Nuclear factor NF-kappa-B p105 subunit	15169888	ABIN-2 forms a ternary complex with TPL-2 and NF-kappa B1 p105 and is essential for TPL-2 protein stability.

Q16595	FRDA_HUMAN	Frataxin, mitochondrial	16608849	A pool of extramitochondrial frataxin that promotes cell survival.

P00334	ADH_DROME	Alcohol dehydrogenase	15581900	Drosophila alcohol dehydrogenase: acetate-enzyme interactions and novel insights into the effects of electrostatics on catalysis.

P37202	DIS3_SCHPO	Exosome complex exonuclease dis3	1944266	The fission yeast dis3+ gene encodes a 110-kDa essential protein implicated in mitotic control.

Q02950	RT51_YEAST	37S ribosomal protein MRP51, mitochondrial	9528754	Functional interactions between yeast mitochondrial ribosomes and mRNA 5' untranslated leaders.

Q16644	MAPK3_HUMAN	MAP kinase-activated protein kinase 3	8626550	Identification of mitogen-activated protein (MAP) kinase-activated protein kinase-3, a novel substrate of CSBP p38 MAP kinase.

Q86B61	TBH1_DROME	Tyramine beta-hydroxylase	14978721	Tyramine and octopamine have opposite effects on the locomotion of Drosophila larvae.

Q16654	PDK4_HUMAN	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial	8798399	Cloning and characterization of PDK4 on 7q21.3 encoding a fourth pyruvate dehydrogenase kinase isoenzyme in human.

P31291	WNT8B_XENLA	Protein Wnt-8b	7635061	Xwnt-8b: a maternally expressed Xenopus Wnt gene with a potential role in establishing the dorsoventral axis.

O60671	RAD1_HUMAN	Cell cycle checkpoint protein RAD1	9716408	Human and mouse homologs of Schizosaccharomyces pombe rad1(+) and Saccharomyces cerevisiae RAD17: linkage to checkpoint control and mammalian meiosis.

Q9NSA0	S22AB_HUMAN	Solute carrier family 22 member 11	15291761	Mutational analysis of histidine residues in human organic anion transporter 4 (hOAT4).

Q04206	TF65_HUMAN	Transcription factor p65	12748188	RING finger protein AO7 supports NF-kappaB-mediated transcription by interacting with the transactivation domain of the p65 subunit.

Q9FEF8	FBRL1_ARATH	rRNA 2'-O-methyltransferase fibrillarin 1	10806224	Molecular cloning and targeting of a fibrillarin homolog from Arabidopsis.

P83291	NCB5R_ARATH	NADH-cytochrome b5 reductase-like protein	11743114	Proteomic approach to identify novel mitochondrial proteins in Arabidopsis.

Q9P6M8	PABPX_SCHPO	mRNA export factor crp79	12181330	Crp79p, like Mex67p, is an auxiliary mRNA export factor in Schizosaccharomyces pombe.

Q13003	GRIK3_HUMAN	Glutamate receptor, ionotropic kainate 3	8128318	Chromosomal localization of gene for human glutamate receptor subunit-7.

Q13257	MD2L1_HUMAN	Mitotic spindle assembly checkpoint protein MAD2A	10527948	Evidence for an interaction of the metalloprotease-disintegrin tumour necrosis factor alpha convertase (TACE) with mitotic arrest deficient 2 (MAD2), and of the metalloprotease-disintegrin MDC9 with a novel MAD2-related protein, MAD2-beta.

Q9Y4C5	CHST2_HUMAN	Carbohydrate sulfotransferase 2	10049591	CHST1 and CHST2 sulfotransferases expressed by human vascular endothelial cells: cDNA cloning, expression, and chromosomal localization.

P21819	DIUH1_MANSE	Diuretic hormone 1	16594029	Isolation and identification of a diuretic hormone from the tobacco hornworm, Manduca sexta.

Q95P07	HCYD_SCUCO	Hemocyanin subunit D	12823556	Complete subunit sequences, structure and evolution of the 6 x 6-mer hemocyanin from the common house centipede, Scutigera coleoptrata.

P52286	SKP1_YEAST	Suppressor of kinetochore protein 1	11283612	Skp1 forms multiple protein complexes, including RAVE, a regulator of V-ATPase assembly.

Q92878	RAD50_HUMAN	DNA repair protein RAD50	9590181	The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response.

Q15653	IKBB_HUMAN	NF-kappa-B inhibitor beta	7776974	Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor.

Q9LY15	MSRA2_ARATH	Peptide methionine sulfoxide reductase A2	15031406	Arabidopsis peptide methionine sulfoxide reductase2 prevents cellular oxidative damage in long nights.

P40565	IST3_YEAST	U2 snRNP component IST3	15565172	Proteomic analysis identifies a new complex required for nuclear pre- mRNA retention and splicing.

Q17353	PAR3_CAEEL	Partitioning defective protein 3	9834192	PAR-6 is a conserved PDZ domain-containing protein that colocalizes with PAR-3 in Caenorhabditis elegans embryos.

Q9H0D6	XRN2_HUMAN	5'-3' exoribonuclease 2	15565158	Human 5' -> 3' exonuclease Xrn2 promotes transcription termination at co-transcriptional cleavage sites.

O95347	SMC2_HUMAN	Structural maintenance of chromosomes protein 2	9789013	Identification of two distinct human SMC protein complexes involved in mitotic chromosome dynamics.

Q9JM51	PTGES_MOUSE	Prostaglandin E synthase	10869354	Regulation of prostaglandin E2 biosynthesis by inducible membrane- associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2.

Q9SD53	Y3720_ARATH	UPF0481 protein At3g47200	16618929	Mapping the Arabidopsis organelle proteome.

Q62422	OSTF1_MOUSE	Osteoclast-stimulating factor 1	9630982	Cloning of ligand targets: systematic isolation of SH3 domain- containing proteins.

Q68CZ6	HAUS3_HUMAN	HAUS augmin-like complex subunit 3	19369198	The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells.

P16235	LSHR_RAT	Lutropin-choriogonadotropic hormone receptor	2502842	Lutropin-choriogonadotropin receptor: an unusual member of the G protein-coupled receptor family.

P13805	TNNT1_HUMAN	Troponin T, slow skeletal muscle	10952871	A novel nemaline myopathy in the Amish caused by a mutation in troponin T1.

Q6NYC1	JMJD6_HUMAN	Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6	14729065	Nuclear localization of the phosphatidylserine receptor protein via multiple nuclear localization signals.

Q9JIT3	TLE3_RAT	Transducin-like enhancer protein 3	10800926	rTLE3, a newly identified transducin-like enhancer of split, is induced by depolarization in brain.

O14735	CDIPT_HUMAN	CDP-diacylglycerol--inositol 3-phosphatidyltransferase	9407135	The role of CDP-diacylglycerol synthetase and phosphatidylinositol synthase activity levels in the regulation of cellular phosphatidylinositol content.

P22987	KIN1_SCHPO	Protein kinase kin1	2236039	A putative protein kinase gene (kin1+) is important for growth polarity in Schizosaccharomyces pombe.

Q24522	BUN1_DROME	Protein bunched, class 1/class 3/D/E isoforms	7555710	Shortsighted acts in the decapentaplegic pathway in Drosophila eye development and has homology to a mouse TGF-beta-responsive gene.

P38879	NACA_YEAST	Nascent polypeptide-associated complex subunit alpha	16926149	The yeast Ccr4-Not complex controls ubiquitination of the nascent- associated polypeptide (NAC-EGD) complex.

Q9CA40	NUDT1_ARATH	Nudix hydrolase 1	17804481	AtNUDX1, an 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate pyrophosphohydrolase, is responsible for eliminating oxidized nucleotides in Arabidopsis.

Q8INB9	AKT1_DROME	RAC serine/threonine-protein kinase	15712201	dAkt kinase controls follicle cell size during Drosophila oogenesis.

P35196	RER2_YEAST	Dehydrodolichyl diphosphate synthase	9858571	The yeast RER2 gene, identified by endoplasmic reticulum protein localization mutations, encodes cis-prenyltransferase, a key enzyme in dolichol synthesis.

O23255	SAHH1_ARATH	Adenosylhomocysteinase 1	15659630	The Arabidopsis HOMOLOGY-DEPENDENT GENE SILENCING1 gene codes for an S-adenosyl-L-homocysteine hydrolase required for DNA methylation- dependent gene silencing.

P32587	PYP3_SCHPO	Tyrosine-protein phosphatase 3	1464318	Pyp3 PTPase acts as a mitotic inducer in fission yeast.

P38907	CHL4_YEAST	Central kinetochore subunit CHL4	9339342	The mcm17 mutation of yeast shows a size-dependent segregational defect of a mini-chromosome.

P49407	ARRB1_HUMAN	Beta-arrestin-1	15878855	{beta}-Arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth factor-1 receptor by acting as adaptor for the MDM2 E3 ligase.

Q9R0L4	CAND2_RAT	Cullin-associated NEDD8-dissociated protein 2	10441524	TIP120B: a novel TIP120-family protein that is expressed specifically in muscle tissues.

Q99728	BARD1_HUMAN	BRCA1-associated RING domain protein 1	12890688	The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitin.

Q61555	FBN2_MOUSE	Fibrillin-2	7744963	Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils.

Q9LF79	ACA8_ARATH	Calcium-transporting ATPase 8, plasma membrane-type	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q570C0	TIR1_ARATH	Protein TRANSPORT INHIBITOR RESPONSE 1	11713520	Auxin regulates SCF(TIR1)-dependent degradation of AUX/IAA proteins.

O14244	YELD_SCHPO	Uncharacterized membrane protein C6F6.13c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q2L4W6	SPO5_SCHPO	Sporulation-specific protein 5	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

Q9ZSK1	GTOMC_ARATH	Tocopherol O-methyltransferase, chloroplastic	9851934	Elevating the vitamin E content of plants through metabolic engineering.

Q8VY97	Y4213_ARATH	UPF0480 protein At4g32130	16618929	Mapping the Arabidopsis organelle proteome.

Q12849	GRSF1_HUMAN	G-rich sequence factor 1	8036161	GRSF-1: a poly(A)+ mRNA binding protein which interacts with a conserved G-rich element.

Q93Z81	CAX3_ARATH	Vacuolar cation/proton exchanger 3	16055687	Functional association of Arabidopsis CAX1 and CAX3 is required for normal growth and ion homeostasis.

Q99PG0	AAAD_MOUSE	Arylacetamide deacetylase	11481320	Characterization of the rodent genes for arylacetamide deacetylase, a putative microsomal lipase, and evidence for transcriptional regulation.

P24389	IOD1_RAT	Type I iodothyronine deiodinase	1825132	Type I iodothyronine deiodinase is a selenocysteine-containing enzyme.

P36192	DEFI_DROME	Defensin	8168509	Characterization and transcriptional profiles of a Drosophila gene encoding an insect defensin. A study in insect immunity.

P01732	CD8A_HUMAN	T-cell surface glycoprotein CD8 alpha chain	2496167	Alternatively spliced mRNA encodes a secreted form of human CD8 alpha. Characterization of the human CD8 alpha gene.

Q14160	SCRIB_HUMAN	Protein scribble homolog	15649318	The tumor suppressor Scrib interacts with the zyxin-related protein LPP, which shuttles between cell adhesion sites and the nucleus.

P35132	UBC9_ARATH	SUMO-conjugating enzyme UBC9	16339806	Genome analysis and functional characterization of the E2 and RING- type E3 ligase ubiquitination enzymes of Arabidopsis.

Q9JIR0	RIMB1_RAT	Peripheral-type benzodiazepine receptor-associated protein 1	9915832	Cloning and characterization of PRAX-1. A new protein that specifically interacts with the peripheral benzodiazepine receptor.

P53297	PBP1_YEAST	PAB1-binding protein 1	9819425	Pbp1p, a factor interacting with Saccharomyces cerevisiae poly(A)- binding protein, regulates polyadenylation.

Q2PS26	ULP1D_ARATH	Ubiquitin-like-specific protease 1D	16740136	Evolution of a signalling system that incorporates both redundancy and diversity: Arabidopsis SUMOylation.

P49677	IAA1_ARATH	Auxin-responsive protein IAA1	7658471	The PS-IAA4/5-like family of early auxin-inducible mRNAs in Arabidopsis thaliana.

Q60520	SIN3A_MOUSE	Paired amphipathic helix protein Sin3a	8649810	Mouse Sin3A interacts with and can functionally substitute for the amino-terminal repression of the Myc antagonist Mxi1.

Q13422	IKZF1_HUMAN	DNA-binding protein Ikaros	8543809	The Ikaros gene encodes a family of lymphocyte-restricted zinc finger DNA binding proteins, highly conserved in human and mouse.

Q9UKV8	AGO2_HUMAN	Protein argonaute-2	19167051	Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs.

P34138	PTP2_DICDI	Tyrosine-protein phosphatase 2	8226777	Cloning and functional expression of a Dictyostelium discoideum protein tyrosine phosphatase.

Q09499	IRE1_CAEEL	Serine/threonine-protein kinase/endoribonuclease ire-1	11779465	Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development.

Q98SP8	EPABA_XENLA	Embryonic polyadenylate-binding protein A	11274061	A novel embryonic poly(A) binding protein, ePAB, regulates mRNA deadenylation in Xenopus egg extracts.

O15553	MEFV_HUMAN	Pyrin	11115844	Alternative splicing at the MEFV locus involved in familial Mediterranean fever regulates translocation of the marenostrin/pyrin protein to the nucleus.

Q8C7R7	RFX6_MOUSE	DNA-binding protein RFX6	20148032	Rfx6 directs islet formation and insulin production in mice and humans.

P53196	RPN14_YEAST	26S proteasome regulatory subunit RPN14	19446323	Multiple proteasome-interacting proteins assist the assembly of the yeast 19S regulatory particle.

Q9R190	MTA2_MOUSE	Metastasis-associated protein MTA2	11749719	Characterization of mouse metastasis-associated gene 2: genomic structure, nuclear localization signal, and alternative potentials as transcriptional activator and repressor.

P54105	ICLN_HUMAN	Methylosome subunit pICln	7887970	Molecular cloning of the human volume-sensitive chloride conductance regulatory protein, pICln, from ocular ciliary epithelium.

Q20334	TNNI1_CAEEL	Troponin I 1	15743415	Tissue expression of four troponin I genes and their molecular interactions with two troponin C isoforms in Caenorhabditis elegans.

Q84XU2	PPP5_ARATH	Serine/threonine-protein phosphatase 5	12972652	The subcellular localization of plant protein phosphatase 5 isoforms is determined by alternative splicing.

Q9JHL4	DBNL_RAT	Drebrin-like protein	15014124	Linkage of the actin cytoskeleton to the postsynaptic density via direct interactions of Abp1 with the ProSAP/Shank family.

P61221	ABCE1_HUMAN	ATP-binding cassette sub-family E member 1	11585831	The 2-5A/RNase L/RNase L inhibitor (RNI) pathway regulates mitochondrial mRNAs stability in interferon alpha-treated H9 cells.

P11927	KAR1_YEAST	Cell division control protein KAR1	3030557	KAR1, a gene required for function of both intranuclear and extranuclear microtubules in yeast.

Q9I931	FUCL1_ANGJA	Fucolectin-1	10924498	Multiplicity, structures, and endocrine and exocrine natures of eel fucose-binding lectins.

Q7DM58	AB4C_ARATH	ABC transporter C family member 4	15225287	Disruption of AtMRP4, a guard cell plasma membrane ABCC-type ABC transporter, leads to deregulation of stomatal opening and increased drought susceptibility.

Q9UTC7	YIDC_SCHPO	Uncharacterized WD repeat-containing protein C227.12	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q96GG9	DCNL1_HUMAN	DCN1-like protein 1	18826954	SCCRO (DCUN1D1) is an essential component of the E3 complex for neddylation.

Q08096	RCL1_YEAST	RNA 3'-terminal phosphate cyclase-like protein	10790377	Rcl1p, the yeast protein similar to the RNA 3'-phosphate cyclase, associates with U3 snoRNP and is required for 18S rRNA biogenesis.

P14956	CECB_DROME	Cecropin-B	2390977	The immune response in Drosophila: pattern of cecropin expression and biological activity.

O95180	CAC1H_HUMAN	Voltage-dependent T-type calcium channel subunit alpha-1H	9670923	Cloning and characterization of alpha1H from human heart, a member of the T-type Ca2+ channel gene family.

Q96AX1	VP33A_HUMAN	Vacuolar protein sorting-associated protein 33A	19109425	SPE-39 family proteins interact with the HOPS complex and function in lysosomal delivery.

P42758	XERO2_ARATH	Dehydrin Xero 2	7948863	Characterization and differential expression of dhn/lea/rab-like genes during cold acclimation and drought stress in Arabidopsis thaliana.

P77239	CUSB_ECOLI	Cation efflux system protein cusB	12813074	Molecular analysis of the copper-transporting efflux system CusCFBA of Escherichia coli.

P40155	PEX17_YEAST	Peroxisomal membrane protein PEX17	9425153	Pex17p of Saccharomyces cerevisiae is a novel peroxin and component of the peroxisomal protein translocation machinery.

P51788	CLCN2_HUMAN	Chloride channel protein 2	7795595	Cloning of a putative human voltage-gated chloride channel (ClC-2) cDNA widely expressed in human tissues.

Q9FN69	GL3_ARATH	Transcription factor GLABRA 3	14561633	A contradictory GLABRA3 allele helps define gene interactions controlling trichome development in Arabidopsis.

P13259	PCY1_YEAST	Choline-phosphate cytidylyltransferase	2826147	Molecular cloning and characterization of the gene encoding cholinephosphate cytidylyltransferase in Saccharomyces cerevisiae.

Q68CP9	ARID2_HUMAN	AT-rich interactive domain-containing protein 2	15640446	DNA-binding properties of ARID family proteins.

P63004	LIS1_RAT	Platelet-activating factor acetylhydrolase IB subunit alpha	9459487	Molecular cloning of cDNAs encoding alpha1, alpha2, and beta subunits of rat brain platelet-activating factor acetylhydrolase.

O94663	SNF8_SCHPO	Vacuolar-sorting protein dot2	11901107	Fission yeast mutants affecting telomere clustering and meiosis- specific spindle pole body integrity.

P47019	ALB1_YEAST	Ribosome biogenesis protein ALB1	16702403	Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes.

P07741	APT_HUMAN	Adenine phosphoribosyltransferase	15196008	Three-dimensional structure of human adenine phosphoribosyltransferase and its relation to DHA-urolithiasis.

O14684	PTGES_HUMAN	Prostaglandin E synthase	10377395	Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target.

Q62765	NLGN1_RAT	Neuroligin-1	9325340	Binding properties of neuroligin 1 and neurexin 1beta reveal function as heterophilic cell adhesion molecules.

Q8VCW4	UN93B_MOUSE	Protein unc-93 homolog B1	16415873	The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9.

O74439	YJE9_SCHPO	Uncharacterized mitochondrial carrier C1682.09c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P62993	GRB2_HUMAN	Growth factor receptor-bound protein 2	8491186	The SH2/SH3 domain-containing protein GRB2 interacts with tyrosine- phosphorylated IRS1 and Shc: implications for insulin control of ras signalling.

P47001	CIS3_YEAST	Cell wall mannoprotein CIS3	15781460	Comprehensive proteomic analysis of Saccharomyces cerevisiae cell walls: identification of proteins covalently attached via glycosylphosphatidylinositol remnants or mild alkali-sensitive linkages.

P26196	DDX6_HUMAN	Probable ATP-dependent RNA helicase DDX6	16364915	Multiple processing body factors and the ARE binding protein TTP activate mRNA decapping.

O94403	YQFB_SCHPO	Uncharacterized RNA-binding protein C126.11c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9USH1	MED31_SCHPO	Mediator of RNA polymerase II transcription subunit 31	12471453	The Schizosaccharomyces pombe genes sep10 and sep11 encode putative general transcriptional regulators involved in multiple cellular processes.

O95166	GBRAP_HUMAN	Gamma-aminobutyric acid receptor-associated protein	9892355	GABA(A)-receptor-associated protein links GABA(A) receptors and the cytoskeleton.

Q9NP58	ABCB6_HUMAN	ATP-binding cassette sub-family B member 6, mitochondrial	11955620	Isolation of a genomic clone containing the promoter region of the human ATP binding cassette (ABC) transporter, ABCB6.

P36056	RT22_YEAST	37S ribosomal protein S22, mitochondrial	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Q8CIQ7	DOCK3_MOUSE	Dedicator of cytokinesis protein 3	10854253	Isolation and characterization of novel presenilin binding protein.

O43683	BUB1_HUMAN	Mitotic checkpoint serine/threonine-protein kinase BUB1	9660858	The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase.

P17610	YPT3_SCHPO	GTP-binding protein ypt3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P47025	MDV1_YEAST	Mitochondrial division protein 1	11038183	Dnm1p GTPase-mediated mitochondrial fission is a multi-step process requiring the novel integral membrane component Fis1p.

Q96JB1	DYH8_HUMAN	Dynein heavy chain 8, axonemal	9373155	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

Q13287	NMI_HUMAN	N-myc-interactor	9989503	Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgamma-mediated signaling.

O81057	ASK14_ARATH	SKP1-like protein 14	14749489	Expression and interaction analysis of Arabidopsis Skp1-related genes.

Q9USW1	YHZ3_SCHPO	Uncharacterized protein C21B10.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O44252	ROST_DROME	Protein rolling stone	9230076	The mesodermal expression of rolling stone (rost) is essential for myoblast fusion in Drosophila and encodes a potential transmembrane protein.

P55345	ANM2_HUMAN	Protein arginine N-methyltransferase 2	9545638	Identification and characterization of two putative human arginine methyltransferases (HRMT1L1 and HRMT1L2).

P34230	PXA2_YEAST	Peroxisomal long-chain fatty acid import protein 1	8876235	A Saccharomyces cerevisiae homolog of the human adrenoleukodystrophy transporter is a heterodimer of two half ATP-binding cassette transporters.

O75192	PX11A_HUMAN	Peroxisomal membrane protein 11A	9792670	Expression of PEX11beta mediates peroxisome proliferation in the absence of extracellular stimuli.

O14259	YFP2_SCHPO	SH3 domain-containing protein C7D4.02c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Z2V6	HDAC5_MOUSE	Histone deacetylase 5	10640276	Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression.

P35193	ATG19_YEAST	Autophagy-related protein 19	15138258	Cargo proteins facilitate the formation of transport vesicles in the cytoplasm to vacuole targeting pathway.

P32597	STH1_YEAST	Nuclear protein STH1/NPS1	10320476	Nps1/Sth1p, a component of an essential chromatin-remodeling complex of Saccharomyces cerevisiae, is required for the maximal expression of early meiotic genes.

P62744	AP2S1_RAT	AP-2 complex subunit sigma	2040623	AP17 and AP19, the mammalian small chains of the clathrin-associated protein complexes show homology to Yap17p, their putative homolog in yeast.

P40358	JEM1_YEAST	DnaJ-like chaperone JEM1	15282802	Localization of proteins that are coordinately expressed with Cln2 during the cell cycle.

Q9W707	FXF1B_XENLA	Forkhead box protein F1-B	15229177	Function and regulation of FoxF1 during Xenopus gut development.

Q09751	LGUL_SCHPO	Lactoylglutathione lyase	15042280	Identification of thermostable glyoxalase I in the fission yeast Schizosaccharomyces pombe.

Q9UIX4	KCNG1_HUMAN	Potassium voltage-gated channel subfamily G member 1	9434767	Isolation, characterization, and mapping of two human potassium channels.

Q9JIA7	SPHK2_MOUSE	Sphingosine kinase 2	10751414	Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform.

O14795	UN13B_HUMAN	Protein unc-13 homolog B	9607201	Cloning of a novel gene in the human kidney homologous to rat munc13s: its potential role in diabetic nephropathy.

Q9EQ16	CXCR6_MOUSE	C-X-C chemokine receptor type 6	11017100	A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo.

Q9W552	VPS26_DROME	Vacuolar protein sorting-associated protein 26	18193032	Wingless secretion promotes and requires retromer-dependent cycling of Wntless.

Q9FIA9	PEP4_ARATH	Elicitor peptide 4	16785434	An endogenous peptide signal in Arabidopsis activates components of the innate immune response.

P47170	IML1_YEAST	Vacuolar membrane-associated protein IML1	14562095	Global analysis of protein localization in budding yeast.

P54609	CD48A_ARATH	Cell division control protein 48 homolog A	15592873	The Arabidopsis SERK1 protein interacts with the AAA-ATPase AtCDC48, the 14-3-3 protein GF14lambda and the PP2C phosphatase KAPP.

Q9SG80	ASD1_ARATH	Alpha-L-arabinofuranosidase 1	15181203	Purification and characterization of enzymes exhibiting beta-D- xylosidase activities in stem tissues of Arabidopsis.

Q8SX83	SPEN_DROME	Protein split ends	10959845	split ends, a new component of the Drosophila EGF receptor pathway, regulates development of midline glial cells.

Q9XVK5	UBC12_CAEEL	NEDD8-conjugating enzyme ubc-12	10993680	The NED-8 conjugating system in Caenorhabditis elegans is required for embryogenesis and terminal differentiation of the hypodermis.

Q04935	COX20_YEAST	Cytochrome c oxidase protein 20, mitochondrial	10671482	Identification of Cox20p, a novel protein involved in the maturation and assembly of cytochrome oxidase subunit 2.

P37028	BTUF_ECOLI	Vitamin B12-binding protein	11790740	Identification of the periplasmic cobalamin-binding protein BtuF of Escherichia coli.

Q9XZE5	PP2AA_DICDI	Serine/threonine-protein phosphatase 2A catalytic subunit A	10452519	Molecular characterization and immunolocalization of Dictyostelium discoideum protein phosphatase 2A.

Q93WC9	IPT3_ARATH	Adenylate isopentenyltransferase 3, chloroplastic	14726522	Distinct isoprenoid origins of cis- and trans-zeatin biosyntheses in Arabidopsis.

Q5SF95	AAAP_ANAMF	Appendage-associated protein	15557651	Identification of a novel Anaplasma marginale appendage-associated protein that localizes with actin filaments during intraerythrocytic infection.

Q8IUH3	RBM45_HUMAN	RNA-binding protein 45	12220514	cDNA cloning and characterization of Drb1, a new member of RRM-type neural RNA-binding protein.

O00327	BMAL1_HUMAN	Aryl hydrocarbon receptor nuclear translocator-like protein 1	9079689	Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway.

P84002	HYB1_HYLBI	Hylin-b1	15638808	Hylins: bombinins H structurally related peptides from the skin secretion of the Brazilian tree-frog Hyla biobeba.

Q9P1W9	PIM2_HUMAN	Serine/threonine-protein kinase pim-2	18675992	Serine/threonine kinase Pim-2 promotes liver tumorigenesis induction through mediating survival and preventing apoptosis of liver cell.

P28576	PDGFA_RAT	Platelet-derived growth factor subunit A	8318539	Conservation in sequence and affinity of human and rodent PDGF ligands and receptors.

Q9VYX1	ENY2_DROME	Enhancer of yellow 2 transcription factor	17643381	Evolutionarily conserved E(y)2/Sus1 protein is essential for the barrier activity of Su(Hw)-dependent insulators in Drosophila.

O95786	DDX58_HUMAN	Probable ATP-dependent RNA helicase DDX58	19609254	RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate.

Q9P6M7	MUG99_SCHPO	Meiotically up-regulated gene 99 protein, mitochondrial	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

Q9C0Z9	RPC9_SCHPO	DNA-directed RNA polymerase III subunit rpc9	16877568	Ancient origin, functional conservation and fast evolution of DNA- dependent RNA polymerase III.

Q92997	DVL3_HUMAN	Segment polarity protein dishevelled homolog DVL-3	20227366	Loss of the tumor suppressor CYLD enhances Wnt/beta-catenin signaling through K63-linked ubiquitination of Dvl.

Q12402	YOP1_YEAST	Protein YOP1	11278413	Yop1p, the yeast homolog of the polyposis locus protein 1, interacts with Yip1p and negatively regulates cell growth.

P53552	THO2_YEAST	THO complex subunit 2	11979277	TREX is a conserved complex coupling transcription with messenger RNA export.

Q9UUK3	YLO3_SCHPO	OTU domain-containing protein C1952.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q10063	EHS1_SCHPO	Calcium influx-promoting protein ehs1	10694511	yam8(+), a Schizosaccharomyces pombe gene, is a potential homologue of the Saccharomyces cerevisiae MID1 gene encoding a stretch-activated Ca(2+)-permeable channel.

O95398	RPGF3_HUMAN	Rap guanine nucleotide exchange factor 3	9853756	Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP.

Q92800	EZH1_HUMAN	Histone-lysine N-methyltransferase EZH1	8921387	Characterization of EZH1, a human homolog of Drosophila Enhancer of zeste near BRCA1.

O34919	YOSS_BACSU	SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase yosS	15939294	Cloning, expression, purification, and characterisation of the dUTPase encoded by the integrated Bacillus subtilis temperate bacteriophage SPbeta.

O75582	KS6A5_HUMAN	Ribosomal protein S6 kinase alpha-5	12628924	Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1).

Q16667	CDKN3_HUMAN	Cyclin-dependent kinase inhibitor 3	12745075	Abolishment of the interaction between cyclin-dependent kinase 2 and Cdk-associated protein phosphatase by a truncated KAP mutant.

Q06787	FMR1_HUMAN	Fragile X mental retardation 1 protein	10556305	A novel RNA-binding nuclear protein that interacts with the fragile X mental retardation (FMR1) protein.

Q9NZB8	MOCS1_HUMAN	Molybdenum cofactor biosynthesis protein 1	12754701	Mutations in the molybdenum cofactor biosynthetic genes MOCS1, MOCS2, and GEPH.

O59763	OCA2_SCHPO	Serine/threonine-protein kinase oca2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P11412	G6PD_YEAST	Glucose-6-phosphate 1-dehydrogenase	2001672	Identification of the structural gene for glucose-6-phosphate dehydrogenase in yeast. Inactivation leads to a nutritional requirement for organic sulfur.

Q07864	DPOE1_HUMAN	DNA polymerase epsilon catalytic subunit A	8486689	Molecular cloning of the cDNA for the catalytic subunit of human DNA polymerase epsilon.

Q8GUM3	AAP5_ARATH	Amino acid permease 5	7608199	Substrate specificity and expression profile of amino acid transporters (AAPs) in Arabidopsis.

Q9FKF6	CCU43_ARATH	Cyclin-U4-3	15197472	Molecular characterization of Arabidopsis PHO80-like proteins, a novel class of CDKA;1-interacting cyclins.

P38742	NPR3_YEAST	Nitrogen permease regulator 3	19521502	A genome-wide screen for regulators of TORC1 in response to amino acid starvation reveals a conserved Npr2/3 complex.

P22361	HNF1A_MOUSE	Hepatocyte nuclear factor 1-alpha	2263635	Molecular cloning, functional expression, and chromosomal localization of mouse hepatocyte nuclear factor 1.

Q9NZQ3	SPN90_HUMAN	NCK-interacting protein with SH3 domain	10619843	The VacA toxin of Helicobacter pylori identifies a new intermediate filament-interacting protein.

O95298	NDUC2_HUMAN	NADH dehydrogenase [ubiquinone] 1 subunit C2	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

Q9NRN7	ADPPT_HUMAN	L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase	18022563	Mechanism and substrate recognition of human holo ACP synthase.

P20795	VPS33_YEAST	Vacuolar protein sorting-associated protein 33	16601699	Purification of active HOPS complex reveals its affinities for phosphoinositides and the SNARE Vam7p.

Q9LRZ0	TPR2_ARATH	Topless-related protein 2	16763149	TOPLESS regulates apical embryonic fate in Arabidopsis.

P43307	SSRA_HUMAN	Translocon-associated protein subunit alpha	10437777	Translocon-associated protein alpha transcripts are induced by granulocyte-macrophage colony-stimulating factor and exhibit complex alternative polyadenylation.

P20485	KICH_YEAST	Choline kinase	2536698	Cloning and characterization of the yeast CKI gene encoding choline kinase and its expression in Escherichia coli.

P38217	IMB2_YEAST	Importin subunit beta-2	8849456	Kap104p: a karyopherin involved in the nuclear transport of messenger RNA binding proteins.

Q9WU60	ATRN_MOUSE	Attractin	11137996	A biochemical function for attractin in agouti-induced pigmentation and obesity.

P41252	SYIC_HUMAN	Isoleucyl-tRNA synthetase, cytoplasmic	8052601	Human cytoplasmic isoleucyl-tRNA synthetase: selective divergence of the anticodon-binding domain and acquisition of a new structural unit.

Q9P6J6	BGLS_SCHPO	Putative beta-glucosidase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9GZT4	SRR_HUMAN	Serine racemase	15193426	Characterization and localization of a human serine racemase.

Q5FWY4	MCM6M_XENLA	Maternal DNA replication licensing factor mcm6	9851868	Evidence for different MCM subcomplexes with differential binding to chromatin in Xenopus.

Q9JM90	STAP1_MOUSE	Signal-transducing adaptor protein 1	10679268	Molecular cloning of murine STAP-1, the stem-cell-specific adaptor protein containing PH and SH2 domains.

Q8LGE3	ARP6_ARATH	Actin-related protein 6	16155178	SUPPRESSOR OF FRIGIDA3 encodes a nuclear ACTIN-RELATED PROTEIN6 required for floral repression in Arabidopsis.

P27701	CD82_HUMAN	CD82 antigen	1842498	A new superfamily of lymphoid and melanoma cell proteins with extensive homology to Schistosoma mansoni antigen Sm23.

P02529	CRGC_RAT	Gamma-crystallin C	6294661	Extensive intragenic sequence homology in two distinct rat lens gamma-crystallin cDNAs suggests duplications of a primordial gene.

Q9Y5K2	KLK4_HUMAN	Kallikrein-4	10438493	Localization of a new prostate-specific antigen-related serine protease gene, KLK4, is evidence for an expanded human kallikrein gene family cluster on chromosome 19q13.3-13.4.

B5LUQ9	FALX7_LITFA	Preprofallaxidin-7	18803332	The fallaxidin peptides from the skin secretion of the eastern dwarf tree frog Litoria fallax. Sequence determination by positive and negative ion electrospray mass spectrometry: antimicrobial activity and cDNA cloning of the fallaxidins.

P07633	PCCB_RAT	Propionyl-CoA carboxylase beta chain, mitochondrial	3464942	Coding sequence of the precursor of the beta subunit of rat propionyl-CoA carboxylase.

P52849	NDST2_HUMAN	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2	9601056	cDNA cloning, genomic organization and chromosomal localization of human heparan glucosaminyl N-deacetylase/N-sulphotransferase-2.

Q62720	ZNT1_RAT	Zinc transporter 1	7882967	Cloning and functional characterization of a mammalian zinc transporter that confers resistance to zinc.

Q9BZW8	CD244_HUMAN	Natural killer cell receptor 2B4	10358138	Human 2B4, an activating NK cell receptor, recruits the protein tyrosine phosphatase SHP-2 and the adaptor signaling protein SAP.

P47075	VTC4_YEAST	Vacuolar transporter chaperone 4	11102525	New components of a system for phosphate accumulation and polyphosphate metabolism in Saccharomyces cerevisiae revealed by genomic expression analysis.

P78310	CXAR_HUMAN	Coxsackievirus and adenovirus receptor	15800062	Neutrophil migration across tight junctions is mediated by adhesive interactions between epithelial CAR and a JAM-like protein on neutrophils.

Q9QZI8	SERC1_MOUSE	Serine incorporator 1	10637174	Identification of a ubiquitous family of membrane proteins and their expression in mouse brain.

P51790	CLCN3_HUMAN	H(+)/Cl(-) exchange transporter 3	12471024	The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator- interacting PDZ proteins.

O82794	AGL24_ARATH	MADS-box protein AGL24	12881501	An Arabidopsis MADS-box protein, AGL24, is specifically bound to and phosphorylated by meristematic receptor-like kinase (MRLK).

P43254	COP1_ARATH	E3 ubiquitin-protein ligase COP1	11226162	Identification of a structural motif that confers specific interaction with the WD40 repeat domain of Arabidopsis COP1.

Q9SU14	NUDT7_ARATH	Nudix hydrolase 7	16154395	Cloning and characterization of an Arabidopsis thaliana Nudix hydrolase homologous to the mammalian GFG protein.

O75419	CDC45_HUMAN	Cell division control protein 45 homolog	9660782	The human homolog of Saccharomyces cerevisiae CDC45.

Q869N2	PAKB_DICDI	Serine/threonine-protein kinase pakB	15509655	Cellular distribution and functions of wild-type and constitutively activated Dictyostelium PakB.

Q05874	NNT1_YEAST	Putative nicotinamide N-methyltransferase	12736687	Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae.

P97764	WBP1_MOUSE	WW domain-binding protein 1	7644498	The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules.

Q9CUU3	SYCP2_MOUSE	Synaptonemal complex protein 2	16717126	Mouse SYCP2 is required for synaptonemal complex assembly and chromosomal synapsis during male meiosis.

Q9NVX0	HAUS2_HUMAN	HAUS augmin-like complex subunit 2	19427217	HAUS, the 8-subunit human augmin complex, regulates centrosome and spindle integrity.

P97302	BACH1_MOUSE	Transcription regulator protein BACH1	8887638	Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site.

O94535	YCA8_SCHPO	Uncharacterized protein C895.08c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q63692	CDC37_RAT	Hsp90 co-chaperone Cdc37	8534368	Molecular cloning and cell cycle-dependent expression of a novel gene that is homologous to cdc37.

Q680Q4	SIZ1_ARATH	E3 SUMO-protein ligase SIZ1	17416732	SIZ1-mediated sumoylation of ICE1 controls CBF3/DREB1A expression and freezing tolerance in Arabidopsis.

P49893	WN11B_XENLA	Protein Wnt-11b	16274967	Role of crescent in convergent extension movements by modulating Wnt signaling in early Xenopus embryogenesis.

Q8WWQ8	STAB2_HUMAN	Stabilin-2	12077138	FEEL-1, a novel scavenger receptor with in vitro bacteria-binding and angiogenesis-modulating activities.

O14213	MU185_SCHPO	Meiotically up-regulated gene 185 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P23457	DIDH_RAT	3-alpha-hydroxysteroid dehydrogenase	1714456	Molecular structure of rat hepatic 3 alpha-hydroxysteroid dehydrogenase. A member of the oxidoreductase gene family.

P63278	AMELX_RAT	Amelogenin, X isoform	8600184	Alternative splicing of amelogenin mRNA from rat incisor ameloblasts.

Q9CR36	GKN1_MOUSE	Gastrokine-1	12851218	A novel mitogenic protein that is highly expressed in cells of the gastric antrum mucosa.

Q9ESE2	TNF11_RAT	Tumor necrosis factor ligand superfamily member 11	11092398	Cloning, sequence and functional characterization of the rat homologue of receptor activator of NF-kB ligand.

Q98998	5HT1A_XENLA	5-hydroxytryptamine receptor 1A	9878840	Characterization of a cloned Xenopus laevis serotonin 5-HT1A receptor expressed in the NIH-3T3 cell line.

Q5FXM5	ACBP_DICDI	Acyl-CoA-binding protein	15897458	Peptide signaling during terminal differentiation of Dictyostelium.

Q92750	TAF4B_HUMAN	Transcription initiation factor TFIID subunit 4B	15601843	Core promoter binding by histone-like TAF complexes.

Q8LDC8	ERF92_ARATH	Ethylene-responsive transcription factor 1B	12509529	ETHYLENE RESPONSE FACTOR1 integrates signals from ethylene and jasmonate pathways in plant defense.

O95391	SLU7_HUMAN	Pre-mRNA-splicing factor SLU7	15181151	Splicing factor hSlu7 contains a unique functional domain required to retain the protein within the nucleus.

P87123	RPB11_SCHPO	DNA-directed RNA polymerase II subunit RPB11	9322754	Gene organization and protein sequence of the small subunits of Schizosaccharomyces pombe RNA polymerase II.

P18181	CD48_MOUSE	CD48 antigen	1383383	CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation.

Q9Y709	SKP1_SCHPO	Suppressor of kinetochore protein 1	11163211	The spike of S phase cyclin Cig2 expression at the G1-S border in fission yeast requires both APC and SCF ubiquitin ligases.

P21802	FGFR2_HUMAN	Fibroblast growth factor receptor 2	8676562	Nucleotide sequences at intron 6 and exon 7 junction of fibroblast growth factor receptor 2 and rapid mutational analysis in Apert syndrome.

P37254	PABS_YEAST	Aminodeoxychorismate synthase	8346682	Para-aminobenzoate synthase gene of Saccharomyces cerevisiae encodes a bifunctional enzyme.

P38969	PNT1_YEAST	Pentamidine resistance factor, mitochondrial	11950926	Cox18p is required for export of the mitochondrially encoded Saccharomyces cerevisiae Cox2p C-tail and interacts with Pnt1p and Mss2p in the inner membrane.

P09493	TPM1_HUMAN	Tropomyosin alpha-1 chain	8205619	Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere.

Q9NBX5	GAGXE_DROME	Nucleic-acid-binding protein from transposon X-element	11405632	The X element, a novel LINE transposable element from Drosophila melanogaster.

Q05682	CALD1_HUMAN	Caldesmon	1555769	Cloning of cDNAs encoding human caldesmons.

P10819	SAHH_DICDI	Adenosylhomocysteinase	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q59385	COPA_ECOLI	Copper-exporting P-type ATPase A	12351646	Biochemical characterization of CopA, the Escherichia coli Cu(I)- translocating P-type ATPase.

Q3ZU82	GOGA5_RAT	Golgin subfamily A member 5	15718469	Golgin tethers define subpopulations of COPI vesicles.

O60061	ALG5_SCHPO	Dolichyl-phosphate beta-glucosyltransferase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P46100	ATRX_HUMAN	Transcriptional regulator ATRX	7874112	Cloning and characterization of a new human Xq13 gene, encoding a putative helicase.

Q6P549	SHIP2_MOUSE	Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2	11343120	The lipid phosphatase SHIP2 controls insulin sensitivity.

O17386	CED8_CAEEL	Cell death abnormality protein 8	10882128	The ced-8 gene controls the timing of programmed cell deaths in C. elegans.

Q9SYS6	DRE1C_ARATH	Dehydration-responsive element-binding protein 1C	9952441	The Arabidopsis CBF gene family is composed of three genes encoding AP2 domain-containing proteins whose expression is regulated by low temperature but not by abscisic acid or dehydration.

Q09013	DMPK_HUMAN	Myotonin-protein kinase	15598648	Myotonic dystrophy protein kinase phosphorylates phospholamban and regulates calcium uptake in cardiomyocyte sarcoplasmic reticulum.

P04075	ALDOA_HUMAN	Fructose-bisphosphate aldolase A	10048322	Crystal structure of human muscle aldolase complexed with fructose 1,6-bisphosphate: mechanistic implications.

Q9JMD7	SC5A7_RAT	High affinity choline transporter 1	10649566	Identification and characterization of the high-affinity choline transporter.

Q12417	PRP46_YEAST	Pre-mRNA-splicing factor PRP46	11884590	Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

Q9Y5E7	PCDB2_HUMAN	Protocadherin beta-2	11322959	The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number.

P52955	LBX1_MOUSE	Transcription factor LBX1	16234809	Lbx1 and Tlx3 are opposing switches in determining GABAergic versus glutamatergic transmitter phenotypes.

Q9EQR3	KCNN1_MOUSE	Small conductance calcium-activated potassium channel protein 1	11267657	Structure and complex transcription pattern of the mouse SK1 KCa channel gene, KCNN1.

P41743	KPCI_HUMAN	Protein kinase C iota type	12725730	Mammalian Lgl forms a protein complex with PAR-6 and aPKC independently of PAR-3 to regulate epithelial cell polarity.

O75494	SRS10_HUMAN	Serine/arginine-rich splicing factor 10	11684676	Serine-arginine (SR) protein-like factors that antagonize authentic SR proteins and regulate alternative splicing.

P17695	GLRX2_YEAST	Glutaredoxin-2, mitochondrial	9571241	The yeast Saccharomyces cerevisiae contains two glutaredoxin genes that are required for protection against reactive oxygen species.

Q60974	NCOR1_MOUSE	Nuclear receptor corepressor 1	12130660	Tissue-specific regulation of retinal and pituitary precursor cell proliferation.

Q14690	RRP5_HUMAN	Protein RRP5 homolog	14624448	Identification of a novel protein from glial cells based on its ability to interact with NF-kappaB subunits.

Q15208	STK38_HUMAN	Serine/threonine-protein kinase 38	7761441	Molecular cloning and characterization of a conserved nuclear serine/threonine protein kinase.

Q54FQ2	PKS30_DICDI	Probable polyketide synthase 30	18164290	Screening of genes involved in cell migration in Dictyostelium.

Q9HC23	PROK2_HUMAN	Prokineticin-2	10580115	The mammalian homologues of frog Bv8 are mainly expressed in spermatocytes.

P28159	SUH_DROME	Suppressor of hairless protein	10673509	Repression by suppressor of hairless and activation by Notch are required to define a single row of single-minded expressing cells in the Drosophila embryo.

Q06226	SGK1_RAT	Serine/threonine-protein kinase Sgk1	10357815	Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway.

Q9S7T1	GTE3_ARATH	Bromodomain-containing protein GTE3, chloroplastic	18502747	The PHD domain of plant PIAS proteins mediates sumoylation of bromodomain GTE proteins.

Q00402	NUM1_YEAST	Nuclear migration protein NUM1	11266443	Cortical Num1p interacts with the dynein intermediate chain Pac11p and cytoplasmic microtubules in budding yeast.

Q6DKE2	DVL3_XENLA	Segment polarity protein dishevelled homolog DVL-3	18552847	Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells.

Q9Y4E1	FA21C_HUMAN	WASH complex subunit FAM21C	19922875	The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex.

Q09855	POF11_SCHPO	F-box/WD repeat-containing protein pof11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O14111	YEJF_SCHPO	C2 domain-containing protein C31G5.15	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O55207	SYNJ2_RAT	Synaptojanin-2	10357812	Recruitment of an alternatively spliced form of synaptojanin 2 to mitochondria by the interaction with the PDZ domain of a mitochondrial outer membrane protein.

P09971	PBAN_BOMMO	PBAN-type neuropeptides	8475067	Precursor polyprotein for multiple neuropeptides secreted from the suboesophageal ganglion of the silkworm Bombyx mori: characterization of the cDNA encoding the diapause hormone precursor and identification of additional peptides.

Q86UE8	TLK2_HUMAN	Serine/threonine-protein kinase tousled-like 2	12660173	Human tousled like kinases are targeted by an ATM- and Chk1-dependent DNA damage checkpoint.

P49435	APT1_YEAST	Adenine phosphoribosyltransferase 1	9864350	APT1, but not APT2, codes for a functional adenine phosphoribosyltransferase in Saccharomyces cerevisiae.

P47027	DPB11_YEAST	DNA replication regulator DPB11	12730134	GINS, a novel multiprotein complex required for chromosomal DNA replication in budding yeast.

Q9QXS7	CMLO5_RAT	Probable N-acetyltransferase CML5	11397015	Overexpression of camello, a member of a novel protein family, reduces blastomere adhesion and inhibits gastrulation in Xenopus laevis.

Q9US60	KLP3_SCHPO	Kinesin-like protein 3	12132578	Cloning and characterization of the kinesin-related protein, Krp1p, in Schizosaccharomyces pombe.

Q680Q4	SIZ1_ARATH	E3 SUMO-protein ligase SIZ1	17905899	The Arabidopsis E3 SUMO ligase SIZ1 regulates plant growth and drought responses.

O14787	TNPO2_HUMAN	Transportin-2	9298975	Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins.

Q9Z0E0	NCDN_MOUSE	Neurochondrin	10231559	Induction of hydroxyapatite resorptive activity in bone marrow cell populations resistant to bafilomycin A1 by a factor with restricted expression to bone and brain, neurochondrin.

O15123	ANGP2_HUMAN	Angiopoietin-2	10766762	Characterization and expression of a novel alternatively spliced human angiopoietin-2.

P01598	KV106_HUMAN	Ig kappa chain V-I region EU	5489770	The covalent structure of a human gamma G-immunoglobulin. VI. Amino acid sequence of the light chain.

P84195	XYNA_GLOTR	Endo-1,4-beta-xylanase Xyn10A	15870328	Processive endoglucanase active in crystalline cellulose hydrolysis by the brown rot basidiomycete Gloeophyllum trabeum.

P58956	G39AA_DROME	Putative gustatory receptor 39a, isoform B	10710312	Candidate taste receptors in Drosophila.

Q15849	UT2_HUMAN	Urea transporter 2	8647271	Molecular characterization of a new urea transporter in the human kidney.

P49739	MCM3M_XENLA	Maternal DNA replication licensing factor mcm3	9851868	Evidence for different MCM subcomplexes with differential binding to chromatin in Xenopus.

Q9JLB4	CUBN_MOUSE	Cubilin	15616221	Expression and role of cubilin in the internalization of nutrients during the peri-implantation development of the rodent embryo.

O94979	SC31A_HUMAN	Protein transport protein Sec31A	17196169	ALG-2 directly binds Sec31A and localizes at endoplasmic reticulum exit sites in a Ca2+-dependent manner.

Q9I930	FUCL2_ANGJA	Fucolectin-2	10924498	Multiplicity, structures, and endocrine and exocrine natures of eel fucose-binding lectins.

Q19969	IMA3_CAEEL	Importin subunit alpha-3	11311162	Germline and developmental roles of the nuclear transport factor importin alpha3 in C. elegans.

Q5AQZ4	AGUA_EMENI	Alpha-glucuronidase A	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

P84782	2SS1_BRAOA	Napin-like polypeptide	15485558	A napin-like polypeptide with translation-inhibitory, trypsin- inhibitory, antiproliferative and antibacterial activities from kale seeds.

Q10426	RIK1_SCHPO	Chromatin modification-related protein rik1	7851795	Mutations derepressing silent centromeric domains in fission yeast disrupt chromosome segregation.

Q9Y8G3	MEX67_SCHPO	mRNA export factor mex67	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P24666	PPAC_HUMAN	Low molecular weight phosphotyrosine protein phosphatase	1587862	Sequencing, cloning, and expression of human red cell-type acid phosphatase, a cytoplasmic phosphotyrosyl protein phosphatase.

P81917	OR43A_DROME	Odorant receptor 43a	16402857	Atypical membrane topology and heteromeric function of Drosophila odorant receptors in vivo.

O43557	TNF14_HUMAN	Tumor necrosis factor ligand superfamily member 14	9462508	LIGHT, a new member of the TNF superfamily, and lymphotoxin alpha are ligands for herpesvirus entry mediator.

Q9PVY9	FXC2A_XENLA	Forkhead box protein C2-A	15656969	Of fox and frogs: fox (fork head/winged helix) transcription factors in Xenopus development.

P01909	DQA1_HUMAN	HLA class II histocompatibility antigen, DQ alpha 1 chain	3584986	Complete sequence of the HLA DQ alpha and DQ beta cDNA from a DR5/DQw3 cell line.

P07320	CRGD_HUMAN	Gamma-crystallin D	12507494	Homology models of human gamma-crystallins: structural study of the extensive charge network in gamma-crystallins.

Q9Z262	CLD6_MOUSE	Claudin-6	9892664	Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands.

Q01476	UBP2_YEAST	Ubiquitin carboxyl-terminal hydrolase 2	1429680	Ubiquitin-specific proteases of Saccharomyces cerevisiae. Cloning of UBP2 and UBP3, and functional analysis of the UBP gene family.

Q6P6S3	BSPRY_RAT	B box and SPRY domain-containing protein	12615066	Characterization of zetin 1/rBSPRY, a novel binding partner of 14-3-3 proteins.

Q13546	RIPK1_HUMAN	Receptor-interacting serine/threonine-protein kinase 1	10356400	The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation.

Q6Q415	RL36_DANRE	60S ribosomal protein L36	15138505	Many ribosomal protein genes are cancer genes in zebrafish.

Q6SA08	TSSK4_HUMAN	Testis-specific serine/threonine-protein kinase 4	15964553	TSSK5, a novel member of the testis-specific serine/threonine kinase family, phosphorylates CREB at Ser-133, and stimulates the CRE/CREB responsive pathway.

Q8WSF3	FDL_DROME	Probable beta-hexosaminidase fdl	10623899	Central brain postembryonic development in Drosophila: implication of genes expressed at the interhemispheric junction.

Q12962	TAF10_HUMAN	Transcription initiation factor TFIID subunit 10	7923369	Human TAFII30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor.

P17123	SPO12_YEAST	Sporulation-specific protein 12	11832211	Separase, polo kinase, the kinetochore protein Slk19, and Spo12 function in a network that controls Cdc14 localization during early anaphase.

Q15768	EFNB3_HUMAN	Ephrin-B3	8808709	Elk-L3, a novel transmembrane ligand for the Eph family of receptor tyrosine kinases, expressed in embryonic floor plate, roof plate and hindbrain segments.

Q60592	MAST2_MOUSE	Microtubule-associated serine/threonine-protein kinase 2	14764729	Microtubule-associated serine/threonine kinase-205 kDa and Fc gamma receptor control IL-12 p40 synthesis and NF-kappa B activation.

Q12133	SPC3_YEAST	Signal peptidase complex subunit SPC3	9148930	In addition to SEC11, a newly identified gene, SPC3, is essential for signal peptidase activity in the yeast endoplasmic reticulum.

Q5XK83	MCM4A_XENLA	DNA replication licensing factor mcm4-A	9214647	Licensing of DNA replication by a multi-protein complex of MCM/P1 proteins in Xenopus eggs.

Q6I9Y2	THOC7_HUMAN	THO complex subunit 7 homolog	15833825	Linking transcriptional elongation and messenger RNA export to metastatic breast cancers.

Q15375	EPHA7_HUMAN	Ephrin type-A receptor 7	7898931	cDNA cloning and tissue distribution of five human EPH-like receptor protein-tyrosine kinases.

Q84P23	4CLL9_ARATH	4-coumarate--CoA ligase-like 9	15677481	A new type of peroxisomal acyl-coenzyme A synthetase from Arabidopsis thaliana has the catalytic capacity to activate biosynthetic precursors of jasmonic acid.

O97148	MTH_DROME	G-protein coupled receptor Mth	12367510	Presynaptic regulation of neurotransmission in Drosophila by the G protein-coupled receptor methuselah.

O74955	TSNAX_SCHPO	Translin-associated protein X homolog	16043634	Cloning and characterization of the Schizosaccharomyces pombe homologs of the human protein translin and the translin-associated protein TRAX.

O13826	RFP1_SCHPO	E3 ubiquitin-protein ligase complex slx8-rfp subunit rfp1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q39255	SKP1A_ARATH	SKP1-like protein 1A	12445118	COI1 links jasmonate signalling and fertility to the SCF ubiquitin- ligase complex in Arabidopsis.

P53836	CA120_YEAST	CCR4-NOT transcriptional complex subunit CAF120	11733989	Purification and characterization of the 1.0 MDa CCR4-NOT complex identifies two novel components of the complex.

P78317	RNF4_HUMAN	E3 ubiquitin ligase RNF4	18408734	RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation.

Q9UKS6	PACN3_HUMAN	Protein kinase C and casein kinase substrate in neurons protein 3	10531379	Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1.

P17157	PHO85_YEAST	Cyclin-dependent protein kinase PHO85	9584169	Cyclin partners determine Pho85 protein kinase substrate specificity in vitro and in vivo: control of glycogen biosynthesis by Pcl8 and Pcl10.

Q61768	KINH_MOUSE	Kinesin-1 heavy chain	9657148	Targeted disruption of mouse conventional kinesin heavy chain, kif5B, results in abnormal perinuclear clustering of mitochondria.

P10153	RNAS2_HUMAN	Non-secretory ribonuclease	2734298	Molecular cloning of the human eosinophil-derived neurotoxin: a member of the ribonuclease gene family.

P62282	RS11_RAT	40S ribosomal protein S11	3838984	Nucleotide sequence of cloned cDNA specific for rat ribosomal protein S11.

O61460	VAB1_CAEEL	Ephrin receptor 1	9506518	The VAB-1 Eph receptor tyrosine kinase functions in neural and epithelial morphogenesis in C. elegans.

O94431	YHKC_SCHPO	Uncharacterized aminotransferase C660.12c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q7YSJ4	PSIF_DICDI	Protein psiF	15947191	A cysteine-rich extracellular protein containing a PA14 domain mediates quorum sensing in Dictyostelium discoideum.

Q9SBA5	ITPK1_ARATH	Inositol-tetrakisphosphate 1-kinase 1	9126335	Characterization of a cDNA encoding Arabidopsis thaliana inositol 1,3,4-trisphosphate 5/6-kinase.

P62483	KCAB2_RAT	Voltage-gated potassium channel subunit beta-2	10477520	Differential stimulation of PKC phosphorylation of potassium channels by ZIP1 and ZIP2.

P48751	B3A3_HUMAN	Anion exchange protein 3	7923606	Molecular cloning, expression, and chromosomal localization of two isoforms of the AE3 anion exchanger from human heart.

Q9JHW1	CBPD_RAT	Carboxypeptidase D	11181555	Identification and nuclear localization of a novel prolactin and cytokine-responsive carboxypeptidase D.

Q07654	TFF3_HUMAN	Trefoil factor 3	8454642	Identification of human intestinal trefoil factor. Goblet cell- specific expression of a peptide targeted for apical secretion.

Q5M969	NANP_RAT	N-acylneuraminate-9-phosphatase	16237198	Identification of the sequence encoding N-acetylneuraminate-9- phosphate phosphatase.

P06241	FYN_HUMAN	Tyrosine-protein kinase Fyn	10790433	Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation.

Q96B26	EXOS8_HUMAN	Exosome complex exonuclease RRP43	15231747	A protein interaction framework for human mRNA degradation.

P32617	IES6_YEAST	Chromatin-remodeling complex subunit IES6	14562095	Global analysis of protein localization in budding yeast.

Q91399	ID3A_XENLA	DNA-binding protein inhibitor ID-3-A	7734394	XIdx, a dominant negative regulator of bHLH function in early Xenopus embryos.

P51532	SMCA4_HUMAN	Transcription activator BRG1	12917342	BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation.

Q01844	EWS_HUMAN	RNA-binding protein EWS	8084618	The EWS gene, involved in Ewing family of tumors, malignant melanoma of soft parts and desmoplastic small round cell tumors, codes for an RNA binding protein with novel regulatory domains.

Q93XM7	MCAT_ARATH	Mitochondrial carnitine/acylcarnitine carrier-like protein	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

O95390	GDF11_HUMAN	Growth/differentiation factor 11	10075854	A novel BMP expressed in developing mouse limb, spinal cord, and tail bud is a potent mesoderm inducer in Xenopus embryos.

O75489	NDUS3_HUMAN	NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial	19463981	Mutations in NDUFAF3 (C3ORF60), encoding an NDUFAF4 (C6ORF66)- interacting complex I assembly protein, cause fatal neonatal mitochondrial disease.

P16370	RPB3_YEAST	DNA-directed RNA polymerase II subunit RPB3	16537912	cis- and trans-Acting determinants of transcription termination by yeast RNA polymerase II.

Q8IMZ5	GR94A_DROME	Putative gustatory receptor 94a	10710312	Candidate taste receptors in Drosophila.

Q06330	SUH_HUMAN	Recombining binding protein suppressor of hairless	9874765	CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex.

P0C5W1	MAP1S_RAT	Microtubule-associated protein 1S	17658481	The NMDAR subunit NR3A interacts with microtubule-associated protein 1S in the brain.

P09848	LPH_HUMAN	Lactase-phlorizin hydrolase	2460343	Complete primary structure of human and rabbit lactase-phlorizin hydrolase: implications for biosynthesis, membrane anchoring and evolution of the enzyme.

Q9BXL6	CAR14_HUMAN	Caspase recruitment domain-containing protein 14	11278692	CARD11 and CARD14 are novel caspase recruitment domain (CARD)/membrane-associated guanylate kinase (MAGUK) family members that interact with Bcl10 and activate NF-kappaB.

Q02487	DSC2_HUMAN	Desmocollin-2	2037591	Desmosomal glycoproteins II and III. Cadherin-like junctional molecules generated by alternative splicing.

O42222	GDF8_DANRE	Growth/differentiation factor 8	15042708	Up-regulation of muscle-specific transcription factors during embryonic somitogenesis of zebrafish (Danio rerio) by knock-down of myostatin-1.

Q12019	MDN1_YEAST	Midasin	12374754	60S pre-ribosome formation viewed from assembly in the nucleolus until export to the cytoplasm.

Q6Q788	APOA5_HUMAN	Apolipoprotein A-V	11577099	Apolipoprotein A-V. A novel apolipoprotein associated with an early phase of liver regeneration.

Q22197	CKI1_CAEEL	Cyclin-dependent kinase inhibitor 1	9716524	Developmental regulation of a cyclin-dependent kinase inhibitor controls postembryonic cell cycle progression in Caenorhabditis elegans.

Q8ND30	LIPB2_HUMAN	Liprin-beta-2	9624153	Liprins, a family of LAR transmembrane protein-tyrosine phosphatase- interacting proteins.

Q6B8I1	MDSP_HUMAN	Dual specificity protein phosphatase 13 isoform MDSP	15252030	Characterization of two distinct dual specificity phosphatases encoded in alternative open reading frames of a single gene located on human chromosome 10q22.2.

P37136	ACES_RAT	Acetylcholinesterase	8417155	Cloning and expression of a rat acetylcholinesterase subunit: generation of multiple molecular forms and complementarity with a Torpedo collagenic subunit.

P16661	ALG1_YEAST	Chitobiosyldiphosphodolichol beta-mannosyltransferase	15044395	Physical interactions between the Alg1, Alg2, and Alg11 mannosyltransferases of the endoplasmic reticulum.

Q12154	GET3_YEAST	ATPase GET3	14562095	Global analysis of protein localization in budding yeast.

Q9USV1	SFR1_SCHPO	Swi5-dependent recombination DNA repair protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q52KB5	ZBT24_DANRE	Zinc finger and BTB domain-containing protein 24	15526281	Bone morphogenetic protein-2 induces expression of murine zinc finger transcription factor ZNF450.

Q13085	ACACA_HUMAN	Acetyl-CoA carboxylase 1	16326698	BRCA1 affects lipid synthesis through its interaction with acetyl-CoA carboxylase.

P25961	PTH1R_RAT	Parathyroid hormone/parathyroid hormone-related peptide receptor	1313566	Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: a single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases intracellular free calcium.

Q6NY15	TSG10_MOUSE	Testis-specific gene 10 protein	14585816	Tsga10 encodes a 65-kilodalton protein that is processed to the 27- kilodalton fibrous sheath protein.

P36135	UTH1_YEAST	Protein UTH1	15247238	Uth1p is involved in the autophagic degradation of mitochondria.

P07896	ECHP_RAT	Peroxisomal bifunctional enzyme	4019459	Molecular cloning and nucleotide sequence of the cDNA for rat peroxisomal enoyl-CoA: hydratase-3-hydroxyacyl-CoA dehydrogenase bifunctional enzyme.

P32962	NRL2_ARATH	Nitrilase 2	8022831	Differential regulation of an auxin-producing nitrilase gene family in Arabidopsis thaliana.

Q90WX8	IGF3_XENLA	Insulin-like growth factor III	11709186	Neural and head induction by insulin-like growth factor signals.

P53778	MK12_HUMAN	Mitogen-activated protein kinase 12	8633070	ERK6, a mitogen-activated protein kinase involved in C2C12 myoblast differentiation.

Q08985	SAM4_YEAST	Homocysteine S-methyltransferase 2	11013242	Reverse methionine biosynthesis from S-adenosylmethionine in eukaryotic cells.

O94639	ZRT1_SCHPO	Zinc-regulated transporter 1	18203864	Response of Schizosaccharomyces pombe to zinc deficiency.

O00471	EXOC5_HUMAN	Exocyst complex component 5	9119050	Identification and characterization of homologues of the exocyst component Sec10p.

P82979	SARNP_HUMAN	SAP domain-containing ribonucleoprotein	11356193	An integrated approach in the discovery and characterization of a novel nuclear protein over-expressed in liver and pancreatic tumors.

O42951	PABC_SCHPO	Putative aminodeoxychorismate lyase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P28263	UBC8_YEAST	Ubiquitin-conjugating enzyme E2-24 kDa	10811607	Ubc8p functions in catabolite degradation of fructose-1, 6- bisphosphatase in yeast.

Q13105	ZBT17_HUMAN	Zinc finger and BTB domain-containing protein 17	14739298	A cleaved form of MAGE-A4 binds to Miz-1 and induces apoptosis in human cells.

Q17381	PHA4_CAEEL	Defective pharyngeal development protein 4	17476212	PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans.

Q9VB30	GR98A_DROME	Putative gustatory receptor 98a	10710312	Candidate taste receptors in Drosophila.

P21784	RAG2_MOUSE	V(D)J recombination-activating protein 2	19448632	RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci.

Q80ZD5	AMGO3_RAT	Amphoterin-induced protein 3	12629050	AMIGO, a transmembrane protein implicated in axon tract development, defines a novel protein family with leucine-rich repeats.

Q9W6A5	OPSG1_DANRE	Green-sensitive opsin-1	10349976	Cloning and characterization of six zebrafish photoreceptor opsin cDNAs and immunolocalization of their corresponding proteins.

P38996	NAB3_YEAST	Nuclear polyadenylated RNA-binding protein 3	7962083	Characterization of nuclear polyadenylated RNA-binding proteins in Saccharomyces cerevisiae.

Q9UJX2	CDC23_HUMAN	Cell division cycle protein 23 homolog	14657031	Mitotic regulation of the human anaphase-promoting complex by phosphorylation.

P38840	ARO9_YEAST	Aromatic amino acid aminotransferase 2	9491082	Phenylalanine- and tyrosine-auxotrophic mutants of Saccharomyces cerevisiae impaired in transamination.

Q5GHF7	IPT_HUMLU	Adenylate isopentenyltransferase	15381407	Molecular cloning, expression, and characterization of adenylate isopentenyltransferase from hop (Humulus lupulus L.).

O65282	CH10C_ARATH	20 kDa chaperonin, chloroplastic	10205903	Chloroplast Cpn20 forms a tetrameric structure in Arabidopsis thaliana.

P85826	DIUX_RHOPR	Diuretic hormone class 2	15626502	Presence and activity of a Dippu-DH31-like peptide in the blood- feeding bug, Rhodnius prolixus.

Q9W497	GR05A_DROME	Gustatory receptor for trehalose	11704765	A Gr receptor is required for response to the sugar trehalose in taste neurons of Drosophila.

Q01415	GALK2_HUMAN	N-acetylgalactosamine kinase	7542884	Comparison of the enzymatic activities of human galactokinase GALK1 and a related human galactokinase protein GK2.

Q8S2T0	GRIP_ARATH	Protein GRIP	15605178	Identification of a Golgi-localised GRIP domain protein from Arabidopsis thaliana.

P20742	PZP_HUMAN	Pregnancy zone protein	2476433	The alpha-macroglobulin bait region. Sequence diversity and localization of cleavage sites for proteinases in five mammalian alpha-macroglobulins.

P34252	SLD2_YEAST	DNA replication regulator SLD2	9742127	Sld2, which interacts with Dpb11 in Saccharomyces cerevisiae, is required for chromosomal DNA replication.

Q9H2X6	HIPK2_HUMAN	Homeodomain-interacting protein kinase 2	12874272	Requirement of the co-repressor homeodomain-interacting protein kinase 2 for ski-mediated inhibition of bone morphogenetic protein- induced transcriptional activation.

Q80TH2	LAP2_MOUSE	Protein LAP2	10878805	ERBIN: a basolateral PDZ protein that interacts with the mammalian ERBB2/HER2 receptor.

Q03957	CTK1_YEAST	CTD kinase subunit alpha	1820212	CTD kinase large subunit is encoded by CTK1, a gene required for normal growth of Saccharomyces cerevisiae.

P01614	KV201_HUMAN	Ig kappa chain V-II region Cum	5586923	The complete amino acid sequence of Bence Jones protein Cum (kappa- type).

Q12467	YP168_YEAST	Uncharacterized protein YPL168W	14562095	Global analysis of protein localization in budding yeast.

P15442	GCN2_YEAST	Serine/threonine-protein kinase GCN2	1739968	Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast.

P41250	SYG_HUMAN	Glycyl-tRNA synthetase	17545306	Long-range structural effects of a Charcot-Marie-Tooth disease- causing mutation in human glycyl-tRNA synthetase.

Q9UNL4	ING4_HUMAN	Inhibitor of growth protein 4	16387653	ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.

B2MVM5	CCLA_CARML	Carnocyclin-A	18552180	Isolation and characterization of carnocyclin a, a novel circular bacteriocin produced by Carnobacterium maltaromaticum UAL307.

Q6P5E6	GGA2_MOUSE	ADP-ribosylation factor-binding protein GGA2	19864490	Consortin, a trans-Golgi network cargo receptor for the plasma membrane targeting and recycling of connexins.

Q9JHG6	RCAN1_MOUSE	Calcipressin-1	10722714	A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling.

Q15056	IF4H_HUMAN	Eukaryotic translation initiation factor 4H	9516461	Purification and characterization of a new eukaryotic protein translation factor. Eukaryotic initiation factor 4H.

Q9QZS3	NUMB_MOUSE	Protein numb homolog	10841580	Mouse numb is an essential gene involved in cortical neurogenesis.

P29373	RABP2_HUMAN	Cellular retinoic acid-binding protein 2	1654334	Molecular cloning of two human cellular retinoic acid-binding proteins (CRABP). Retinoic acid-induced expression of CRABP-II but not CRABP-I in adult human skin in vivo and in skin fibroblasts in vitro.

Q9V5M6	LOLA5_DROME	Longitudinals lacking protein, isoforms J/P/Q/S/Z	11880341	Lola regulates midline crossing of CNS axons in Drosophila.

P08603	CFAH_HUMAN	Complement factor H	9312129	Human factor H deficiency. Mutations in framework cysteine residues and block in H protein secretion and intracellular catabolism.

P49766	VEGFB_MOUSE	Vascular endothelial growth factor B	8702615	Genomic organization of the mouse and human genes for vascular endothelial growth factor B (VEGF-B) and characterization of a second splice isoform.

Q8T940	UBX_JUNCO	Homeotic protein ultrabithorax	11859369	Evolution of a transcriptional repression domain in an insect Hox protein.

Q63495	RAGE_RAT	Advanced glycosylation end product-specific receptor	19910580	S100B interaction with the receptor for advanced glycation end products (RAGE): a novel receptor-mediated mechanism for myocyte apoptosis postinfarction.

P33749	MSN4_YEAST	Zinc finger protein MSN4	8641288	The Saccharomyces cerevisiae zinc finger proteins Msn2p and Msn4p are required for transcriptional induction through the stress response element (STRE).

Q9Z1C7	RPGF4_RAT	Rap guanine nucleotide exchange factor 4	9856955	A family of cAMP-binding proteins that directly activate rap1.

Q70UQ0	IKIP_HUMAN	Inhibitor of nuclear factor kappa-B kinase-interacting protein	15389287	A highly conserved proapoptotic gene, IKIP, located next to the APAF1 gene locus, is regulated by p53.

Q9UPN7	PP6R1_HUMAN	Serine/threonine-protein phosphatase 6 regulatory subunit 1	18186651	Protein phosphatase 6 regulatory subunits composed of ankyrin repeat domains.

Q9NWT6	HIF1N_HUMAN	Hypoxia-inducible factor 1-alpha inhibitor	12446723	Structure of factor-inhibiting hypoxia-inducible factor (HIF) reveals mechanism of oxidative modification of HIF-1 alpha.

Q06507	ATF4_MOUSE	Cyclic AMP-dependent transcription factor ATF-4	16751105	SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation.

P78966	MAM1_SCHPO	Mating factor M secretion protein mam1	9236781	The Schizosaccharomyces pombe mam1 gene encodes an ABC transporter mediating secretion of M-factor.

P07283	PMM_YEAST	Phosphomannomutase	3905826	Characterization of a gene product (Sec53p) required for protein assembly in the yeast endoplasmic reticulum.

Q03213	HOT1_YEAST	High-osmolarity-induced transcription protein 1	10722658	The transcriptional response of Saccharomyces cerevisiae to osmotic shock. Hot1p and Msn2p/Msn4p are required for the induction of subsets of high osmolarity glycerol pathway-dependent genes.

Q9NYG5	APC11_HUMAN	Anaphase-promoting complex subunit 11	16364912	Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C.

Q86V81	THOC4_HUMAN	THO complex subunit 4	17190602	Human mRNA export machinery recruited to the 5' end of mRNA.

P84676	SC27_TITCA	Toxin Tc27	15025998	Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

P76469	RHMA_ECOLI	2-keto-3-deoxy-L-rhamnonate aldolase	18754683	Crystal structure and functional assignment of YfaU, a metal ion dependent class II aldolase from Escherichia coli K12.

Q9Y6Y8	S23IP_HUMAN	SEC23-interacting protein	10400679	p125 is a novel mammalian Sec23p-interacting protein with structural similarity to phospholipid-modifying proteins.

Q9TW28	MYOM_DICDI	Myosin-M heavy chain	11208126	The tail domain of myosin M catalyses nucleotide exchange on Rac1 GTPases and can induce actin-driven surface protrusions.

O94338	YHM5_SCHPO	AN1-type zinc finger protein C1271.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NZ43	USE1_HUMAN	Vesicle transport protein USE1	15272311	Involvement of BNIP1 in apoptosis and endoplasmic reticulum membrane fusion.

Q63764	AZIN1_RAT	Antizyme inhibitor 1	9349715	Cloning and sequencing of a human cDNA encoding ornithine decarboxylase antizyme inhibitor.

P41250	SYG_HUMAN	Glycyl-tRNA synthetase	7753621	Cloning, sequencing and bacterial expression of human glycine tRNA synthetase.

P01707	LV204_HUMAN	Ig lambda chain V-II region TRO	118915	Rule of antibody structure. Primary structure of a human monoclonal IgAl-immunoglobulin (myeloma protein Tro). VI. Amino acid sequence of the L-chain, lambda-type, subgroup II.

Q8I5I1	YL135_PLAF7	Uncharacterized protein PFL1135c	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

P38427	TSL1_YEAST	Trehalose synthase complex regulatory subunit TSL1	8404905	Cloning of two related genes encoding the 56-kDa and 123-kDa subunits of trehalose synthase from the yeast Saccharomyces cerevisiae.

Q9JKW0	AR6P1_MOUSE	ADP-ribosylation factor-like protein 6-interacting protein 1	10508919	A novel ADP-ribosylation like factor (ARL-6), interacts with the protein-conducting channel SEC61beta subunit.

O35789	B3GA1_RAT	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1	9177175	Cloning and functional expression of a novel glucuronyltransferase involved in the biosynthesis of the carbohydrate epitope HNK-1.

O95750	FGF19_HUMAN	Fibroblast growth factor 19	12815072	Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis.

Q9R193	AT1B4_RAT	Protein ATP1B4	17592128	Evolution of Na,K-ATPase betam-subunit into a coregulator of transcription in placental mammals.

Q13751	LAMB3_HUMAN	Laminin subunit beta-3	7774918	Cloning of the beta 3 chain gene (LAMB3) of human laminin 5, a candidate gene in junctional epidermolysis bullosa.

P42745	UBC2_ARATH	Ubiquitin-conjugating enzyme E2 2	9371881	Arabidopsis thaliana RAD6 homolog AtUBC2 complements UV sensitivity, but not N-end rule degradation deficiency, of Saccharomyces cerevisiae rad6 mutants.

P36929	RSMB_ECOLI	Ribosomal RNA small subunit methyltransferase B	10026269	Purification, cloning, and characterization of the 16S RNA m5C967 methyltransferase from Escherichia coli.

P78536	ADA17_HUMAN	Disintegrin and metalloproteinase domain-containing protein 17	9034191	Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha.

Q9Z184	PADI3_MOUSE	Protein-arginine deiminase type-3	10092850	Molecular cloning of cDNAs of mouse peptidylarginine deiminase type I, type III and type IV, and the expression pattern of type I in mouse.

Q92665	RT31_HUMAN	28S ribosomal protein S31, mitochondrial	8567980	Imogen 38: a novel 38-kD islet mitochondrial autoantigen recognized by T cells from a newly diagnosed type 1 diabetic patient.

Q91926	VENT1_XENLA	Homeobox protein vent1	9545242	Xvent-1 mediates BMP-4-induced suppression of the dorsal-lip-specific early response gene XFD-1' in Xenopus embryos.

P46645	AAT2_ARATH	Aspartate aminotransferase, cytoplasmic isozyme 1	7894512	The aspartate aminotransferase gene family of Arabidopsis encodes isoenzymes localized to three distinct subcellular compartments.

P83625	HBB2_PSEUR	Hemoglobin subunit beta-2	15340169	Structure and function of the Gondwanian hemoglobin of Pseudaphritis urvillii, a primitive notothenioid fish of temperate latitudes.

P43632	KI2S4_HUMAN	Killer cell immunoglobulin-like receptor 2DS4	7749980	Molecular clones of the p58 NK cell receptor reveal immunoglobulin- related molecules with diversity in both the extra- and intracellular domains.

Q39083	DI191_ARATH	Protein DEHYDRATION-INDUCED 19	7823904	Abscisic acid-dependent and -independent regulation of gene expression by progressive drought in Arabidopsis thaliana.

Q21502	MEP1_CAEEL	MOG interacting and ectopic P-granules protein 1	15151984	Roles of the C. elegans cyclophilin-like protein MOG-6 in MEP-1 binding and germline fates.

Q61091	FZD8_MOUSE	Frizzled-8	16543246	Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression.

P08525	QCR8_YEAST	Cytochrome b-c1 complex subunit 8	10873857	Structure at 2.3 A resolution of the cytochrome bc1 complex from the yeast Saccharomyces cerevisiae co-crystallized with an antibody Fv fragment.

Q9UPM6	LHX6_HUMAN	LIM/homeobox protein Lhx6	10393337	A brain region-specific gene product Lhx6.1 interacts with Ldb1 through tandem LIM-domains.

P38629	RFC3_YEAST	Replication factor C subunit 3	11486023	Chl12 (Ctf18) forms a novel replication factor C-related complex and functions redundantly with Rad24 in the DNA replication checkpoint pathway.

Q0E9G3	KTU_DROME	Protein kintoun	17007873	Towards a comprehensive analysis of the protein phosphatase 1 interactome in Drosophila.

P38222	RKM3_YEAST	Ribosomal N-lysine methyltransferase 3	14562095	Global analysis of protein localization in budding yeast.

Q92844	TANK_HUMAN	TRAF family member-associated NF-kappa-B activator	12005438	Downstream regulator TANK binds to the CD40 recognition site on TRAF3.

P11325	SYLM_YEAST	Leucyl-tRNA synthetase, mitochondrial	1990003	Purification and characterization of the Saccharomyces cerevisiae mitochondrial leucyl-tRNA synthetase.

O48538	RBOHF_ARATH	Respiratory burst oxidase homolog protein F	11756663	Arabidopsis gp91phox homologues AtrbohD and AtrbohF are required for accumulation of reactive oxygen intermediates in the plant defense response.

P70584	ACDSB_RAT	Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial	8660691	Cloning of a cDNA for short/branched chain acyl-Coenzyme A dehydrogenase from rat and characterization of its tissue expression and substrate specificity.

P38772	BCD1_YEAST	Box C/D snoRNA protein 1	12837249	A panoramic view of yeast noncoding RNA processing.

Q84WM7	PPME1_ARATH	Pectinesterase PPME1	17971035	Elaborate spatial patterning of cell-wall PME and PMEI at the pollen tube tip involves PMEI endocytosis, and reflects the distribution of esterified and de-esterified pectins.

Q9US41	URG1_SCHPO	Uracil-regulated protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q15119	PDK2_HUMAN	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial	16401071	Regulatory roles of the N-terminal domain based on crystal structures of human pyruvate dehydrogenase kinase 2 containing physiological and synthetic ligands.

Q07904	THI73_YEAST	Thiamine pathway transporter THI73	16850348	Pdc2 coordinates expression of the THI regulon in the yeast Saccharomyces cerevisiae.

Q9I7U4	TITIN_DROME	Titin	9548712	Human autoantibodies reveal titin as a chromosomal protein.

P48561	TRF5_YEAST	Poly(A) RNA polymerase protein 1	17179095	Contribution of Trf4/5 and the nuclear exosome to genome stability through regulation of histone mRNA levels in Saccharomyces cerevisiae.

Q8VHD8	HORN_MOUSE	Hornerin	11572870	Hornerin, a novel profilaggrin-like protein and differentiation- specific marker isolated from mouse skin.

Q9P7V3	TSN1_SCHPO	Translin-1	16043634	Cloning and characterization of the Schizosaccharomyces pombe homologs of the human protein translin and the translin-associated protein TRAX.

O94491	YC7A_SCHPO	Uncharacterized transporter C417.10	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q6QZQ4	VMAC_RAT	Vimentin-type intermediate filament-associated coiled-coil protein	14985129	Vmac: a novel protein associated with vimentin-type intermediate filament in podocytes of rat kidney.

Q9V4P1	ANLN_DROME	Actin-binding protein anillin	7559773	Anillin, a contractile ring protein that cycles from the nucleus to the cell cortex.

P69874	POTA_ECOLI	Spermidine/putrescine import ATP-binding protein PotA	8366082	Functions of potA and potD proteins in spermidine-preferential uptake system in Escherichia coli.

O93507	TAL1_DANRE	T-cell acute lymphocytic leukemia protein 1 homolog	15617691	Zebrafish scl functions independently in hematopoietic and endothelial development.

P09497	CLCB_HUMAN	Clathrin light chain B	3267234	Structure of human clathrin light chains. Conservation of light chain polymorphism in three mammalian species.

P25586	KRR1_YEAST	Ribosomal RNA assembly protein KRR1	15590835	The small-subunit processome is a ribosome assembly intermediate.

Q24478	CP190_DROME	Centrosome-associated zinc finger protein CP190	9247191	Two proteins that cycle asynchronously between centrosomes and nuclear structures: Drosophila CP60 and CP190.

P38122	PANB_YEAST	3-methyl-2-oxobutanoate hydroxymethyltransferase	11154694	Saccharomyces cerevisiae is capable of de novo pantothenic acid biosynthesis involving a novel pathway of beta-alanine production from spermine.

P35524	CLCN1_RAT	Chloride channel protein 1	1659664	Primary structure and functional expression of a developmentally regulated skeletal muscle chloride channel.

P0CG80	UBIQI_DICDI	Polyubiquitin-I	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

P46948	RRP41_YEAST	Exosome complex component SKI6	9390555	The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases.

Q19705	ARL2_CAEEL	ADP-ribosylation factor-like protein 2	12015966	The C. elegans evl-20 gene is a homolog of the small GTPase ARL2 and regulates cytoskeleton dynamics during cytokinesis and morphogenesis.

P14832	CYPH_YEAST	Peptidyl-prolyl cis-trans isomerase	11641409	Cyclophilin A mediates Vid22p function in the import of fructose-1,6- bisphosphatase into Vid vesicles.

P26951	IL3RA_HUMAN	Interleukin-3 receptor subunit alpha	1833064	Expression cloning of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors.

P10081	IF4A_YEAST	ATP-dependent RNA helicase eIF4A	10409745	Eukaryotic translation initiation factors 4G and 4A from Saccharomyces cerevisiae interact physically and functionally.

Q99741	CDC6_HUMAN	Cell division control protein 6 homolog	9566895	Human CDC6/Cdc18 associates with Orc1 and cyclin-cdk and is selectively eliminated from the nucleus at the onset of S phase.

Q76L33	PCYAB_ASTLO	Photoactivated adenylate cyclase subunit beta	14630964	Photoactivated adenylyl cyclase controls phototaxis in the flagellate Euglena gracilis.

Q9JJZ9	CNGB3_MOUSE	Cyclic nucleotide-gated cation channel beta-3	10662822	Molecular cloning and functional characterization of a new modulatory cyclic nucleotide-gated channel subunit from mouse retina.

Q20679	PLOD_CAEEL	Procollagen-lysine,2-oxoglutarate 5-dioxygenase	11071784	The let-268 locus of Caenorhabditis elegans encodes a procollagen lysyl hydroxylase that is essential for type IV collagen secretion.

Q01151	CD83_HUMAN	CD83 antigen	8422464	Subtractive cDNA cloning of a novel member of the Ig gene superfamily expressed at high levels in activated B lymphocytes.

Q8CH77	NAV1_MOUSE	Neuron navigator 1	15797708	Mouse neuron navigator 1, a novel microtubule-associated protein involved in neuronal migration.

P70539	ACV1C_RAT	Activin receptor type-1C	11084022	The orphan receptor serine/threonine kinase ALK7 signals arrest of proliferation and morphological differentiation in a neuronal cell line.

Q9W0K4	BAB2_DROME	Protein bric-a-brac 2	11973274	The bric a brac locus consists of two paralogous genes encoding BTB/POZ domain proteins and acts as a homeotic and morphogenetic regulator of imaginal development in Drosophila.

Q9SSG3	HIPL1_ARATH	HIPL1 protein	12805588	Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis.

Q64151	SEM4C_MOUSE	Semaphorin-4C	11134026	Sema4c, a transmembrane semaphorin, interacts with a post-synaptic density protein, PSD-95.

P55107	BMP3B_HUMAN	Bone morphogenetic protein 3B	8679252	Growth/differentiation factor-10: a new member of the transforming growth factor-beta superfamily related to bone morphogenetic protein- 3.

Q9LTC0	Y5707_ARATH	Probable receptor-like protein kinase At5g47070	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P63095	GNAS2_RAT	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	3086867	Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide-binding proteins Gs, Gi, and Go from rat brain.

Q9HCU0	CD248_HUMAN	Endosialin	10947988	Genes expressed in human tumor endothelium.

Q9VMA3	CUP_DROME	Protein cup	14691132	Cup is an eIF4E binding protein required for both the translational repression of oskar and the recruitment of Barentsz.

Q80U87	UBP8_MOUSE	Ubiquitin carboxyl-terminal hydrolase 8	16771824	A deubiquitinating enzyme UBPY regulates the level of protein ubiquitination on endosomes.

P53102	MND1_YEAST	Meiotic nuclear division protein 1	11940665	The Mnd1 protein forms a complex with Hop2 to promote homologous chromosome pairing and meiotic double-strand break repair.

Q38873	CDPK7_ARATH	Calcium-dependent protein kinase 7	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P04197	MYB_DROME	Myb protein	12490953	Role for a Drosophila Myb-containing protein complex in site-specific DNA replication.

P08579	RU2B_HUMAN	U2 small nuclear ribonucleoprotein B''	9716128	Crystal structure of the spliceosomal U2B'-U2A' protein complex bound to a fragment of U2 small nuclear RNA.

Q94AI7	TPL_ARATH	Protein TOPLESS	20360743	NINJA connects the co-repressor TOPLESS to jasmonate signalling.

Q03761	TAF12_YEAST	Transcription initiation factor TFIID subunit 12	12138208	Molecular characterization of Saccharomyces cerevisiae TFIID.

A0JPK3	ZFP57_RAT	Zinc finger protein 57	15070898	Identification and characterization of ZFP-57, a novel zinc finger transcription factor in the mammalian peripheral nervous system.

Q12933	TRAF2_HUMAN	TNF receptor-associated factor 2	10521462	TNIK, a novel member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and regulates the cytoskeleton.

Q6RHW0	K1C9_MOUSE	Keratin, type I cytoskeletal 9	16015579	Sperm tail abnormalities in mutant mice with neo(r) gene insertion into an intron of the keratin 9 gene.

O94684	TFB3_SCHPO	RNA polymerase II transcription factor B subunit 3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P38307	DER1_YEAST	Degradation in the endoplasmic reticulum protein 1	8631297	Der1, a novel protein specifically required for endoplasmic reticulum degradation in yeast.

O59824	YME1_SCHPO	ATP-dependent zinc metalloprotease YME1 homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P53088	CTU1_YEAST	Cytoplasmic tRNA 2-thiolation protein 1	18664566	Thio-modification of yeast cytosolic tRNA requires a ubiquitin- related system that resembles bacterial sulfur transfer systems.

Q10758	K2C8_RAT	Keratin, type II cytoskeletal 8	1370816	Regulation of basal and luminal cell-specific cytokeratin expression in rat accessory sex organs. Evidence for a new class of androgen- repressed genes and insight into their pairwise control.

Q15759	MK11_HUMAN	Mitogen-activated protein kinase 11	8663524	Characterization of the structure and function of a new mitogen- activated protein kinase (p38beta).

P30052	SCAL_DROME	Protein scalloped	9869635	Molecular interactions between Vestigial and Scalloped promote wing formation in Drosophila.

Q91YE9	5NT1B_MOUSE	Cytosolic 5'-nucleotidase 1B	11690631	Cloning of a mouse cytosolic 5'-nucleotidase-I identifies a new gene related to human autoimmune infertility-related protein.

O15431	COPT1_HUMAN	High affinity copper uptake protein 1	9207117	hCTR1: a human gene for copper uptake identified by complementation in yeast.

Q04491	SEC13_YEAST	Protein transport protein SEC13	10747086	Structure and assembly of the Nup84p complex.

O74418	SNUT3_SCHPO	U4/U6.U5 tri-snRNP-associated protein 3-like protein C162.01c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12830	BPTF_HUMAN	Nucleosome-remodeling factor subunit BPTF	14609955	Isolation of human NURF: a regulator of Engrailed gene expression.

Q7KRW1	TRC8_DROME	Protein TRC8 homolog	12032852	The TRC8 hereditary kidney cancer gene suppresses growth and functions with VHL in a common pathway.

P23347	B3A2_RAT	Anion exchange protein 2	2294114	cDNA cloning and tissue distribution of mRNAs for two proteins that are related to the band 3 Cl-/HCO3-exchanger.

Q96J01	THOC3_HUMAN	THO complex subunit 3	18974867	Recruitment of the complete hTREX complex is required for Kaposi's sarcoma-associated herpesvirus intronless mRNA nuclear export and virus replication.

Q9LID0	LDL2_ARATH	Lysine-specific histone demethylase 1 homolog 2	17921315	Arabidopsis relatives of the human lysine-specific demethylase1 repress the expression of FWA and FLOWERING LOCUS C and thus promote the floral transition.

Q7RTR2	NLRC3_HUMAN	Protein NLRC3	15705585	CATERPILLER 16.2 (CLR16.2), a novel NBD/LRR family member that negatively regulates T cell function.

P01149	MFAL1_YEAST	Mating factor alpha-1	6306574	Saccharomyces cerevisiae contains two discrete genes coding for the alpha-factor pheromone.

Q68KI4	NHX1_ARATH	Sodium/hydrogen exchanger 1	11707435	The Arabidopsis Na(+)/H(+) exchanger AtNHX1 catalyzes low affinity Na(+) and K(+) transport in reconstituted liposomes.

Q9ULD4	BRPF3_HUMAN	Bromodomain and PHD finger-containing protein 3	16387653	ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.

P50748	KNTC1_HUMAN	Kinetochore-associated protein 1	11146660	Human Zw10 and ROD are mitotic checkpoint proteins that bind to kinetochores.

P19018	TRA2_DROME	Transformer-2 sex-determining protein	2120049	Alternatively spliced transcripts of the sex-determining gene tra-2 of Drosophila encode functional proteins of different size.

O95445	APOM_HUMAN	Apolipoprotein M	10531326	A novel human apolipoprotein (apoM).

Q04491	SEC13_YEAST	Protein transport protein SEC13	8432727	Cytosolic Sec13p complex is required for vesicle formation from the endoplasmic reticulum in vitro.

Q9UBR2	CATZ_HUMAN	Cathepsin Z	9642240	Cathepsin Z, a novel human cysteine proteinase with a short propeptide domain and a unique chromosomal location.

O17386	CED8_CAEEL	Cell death abnormality protein 8	9927601	Genetic control of programmed cell death in the Caenorhabditis elegans hermaphrodite germline.

P33302	PDR5_YEAST	Pleiotropic ABC efflux transporter of multiple drugs	8810273	The ATP binding cassette transporters Pdr5 and Snq2 of Saccharomyces cerevisiae can mediate transport of steroids in vivo.

Q7Z6J0	SH3R1_HUMAN	Putative E3 ubiquitin-protein ligase SH3RF1	17535800	Regulation of the pro-apoptotic scaffolding protein POSH by Akt.

O94268	NOP2_SCHPO	Putative ribosomal RNA methyltransferase nop2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O94276	YORS_SCHPO	Meiotic chromosome segregation protein P8B7.28c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P31057	PANB_ECOLI	3-methyl-2-oxobutanoate hydroxymethyltransferase	776976	Ketopantoate hydroxymethyltransferase. I. Purification and role in pantothenate biosynthesis.

Q9JL55	GDE1_RAT	Glycerophosphodiester phosphodiesterase 1	10760272	MIR16, a putative membrane glycerophosphodiester phosphodiesterase, interacts with RGS16.

Q62838	MUSK_RAT	Muscle, skeletal receptor tyrosine protein kinase	12220490	Crystal structure of the MuSK tyrosine kinase: insights into receptor autoregulation.

P13569	CFTR_HUMAN	Cystic fibrosis transmembrane conductance regulator	15247260	Myosin VI regulates endocytosis of the cystic fibrosis transmembrane conductance regulator.

O00308	WWP2_HUMAN	NEDD4-like E3 ubiquitin-protein ligase WWP2	9169421	Identification of novel human WW domain-containing proteins by cloning of ligand targets.

P25932	ESCA_DROME	Protein escargot	11902678	mgm 1, the earliest sex-specific germline marker in Drosophila, reflects expression of the gene esg in male stem cells.

P98160	PGBM_HUMAN	Basement membrane-specific heparan sulfate proteoglycan core protein	12604605	Perlecan protein core interacts with extracellular matrix protein 1 (ECM1), a glycoprotein involved in bone formation and angiogenesis.

Q07468	VAM6_YEAST	Vacuolar morphogenesis protein 6	9111041	Vam2/Vps41p and Vam6/Vps39p are components of a protein complex on the vacuolar membranes and involved in the vacuolar assembly in the yeast Saccharomyces cerevisiae.

Q10576	P4HA1_CAEEL	Prolyl 4-hydroxylase subunit alpha-1	12036960	The exoskeleton collagens in Caenorhabditis elegans are modified by prolyl 4-hydroxylases with unique combinations of subunits.

O43683	BUB1_HUMAN	Mitotic checkpoint serine/threonine-protein kinase BUB1	17981135	Human Blinkin/AF15q14 is required for chromosome alignment and the mitotic checkpoint through direct interaction with Bub1 and BubR1.

O94389	CC124_SCHPO	Coiled-coil domain-containing protein 124 homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O15392	BIRC5_HUMAN	Baculoviral IAP repeat-containing protein 5	14610074	Aurora-B phosphorylation in vitro identifies a residue of survivin that is essential for its localization and binding to inner centromere protein (INCENP) in vivo.

P42835	EGT2_YEAST	Protein EGT2	8668141	EGT2 gene transcription is induced predominantly by Swi5 in early G1.

Q9JJS8	MASP2_RAT	Mannan-binding lectin serine protease 2	10586086	The rat and mouse homologues of MASP-2 and MAp19, components of the mannan-binding lectin activation pathway of complement.

P23542	AATC_YEAST	Aspartate aminotransferase, cytoplasmic	9288922	Cytosolic aspartate aminotransferase encoded by the AAT2 gene is targeted to the peroxisomes in oleate-grown Saccharomyces cerevisiae.

P84688	SC50_TITCA	Toxin Tc50	15025998	Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

Q04847	YM8A_YEAST	SCF E3 ubiquitin ligase complex F-box protein YMR258C	14562095	Global analysis of protein localization in budding yeast.

Q9SYX2	SPA1_ARATH	Protein SUPPRESSOR OF PHYA-105 1	16854975	Arabidopsis SPA proteins regulate photoperiodic flowering and interact with the floral inducer CONSTANS to regulate its stability.

P49333	ETR1_ARATH	Ethylene receptor 1	9974395	A copper cofactor for the ethylene receptor ETR1 from Arabidopsis.

Q12348	CSN10_YEAST	COP9 signalosome complex subunit 10	12446563	COP9 signalosome components play a role in the mating pheromone response of S. cerevisiae.

Q14236	EPAG_HUMAN	Early lymphoid activation gene protein	8133036	Properties of a novel gene isolated from a Hodgkin's disease cell line that is expressed early during lymphoid cell activation.

Q8NET5	NFAM1_HUMAN	NFAT activation molecule 1	12615919	Calcineurin/nuclear factors of activated T cells (NFAT)-activating and immunoreceptor tyrosine-based activation motif (ITAM)-containing protein (CNAIP), a novel ITAM-containing protein that activates the calcineurin/NFAT-signaling pathway.

P36896	ACV1B_HUMAN	Activin receptor type-1B	8397373	Activin receptor-like kinases: a novel subclass of cell-surface receptors with predicted serine/threonine kinase activity.

Q24093	ABHD2_DROME	Abhydrolase domain-containing protein 2	12612838	Alpha/beta hydrolase2, a predicated gene adjacent to mad in Drosophila melanogaster, belongs to a new global multigene family and is associated with obesity.

Q17868	CKS1_CAEEL	Cyclin-dependent kinases regulatory subunit	11102813	Depletion of a Cks homolog in C. elegans embryos uncovers a post- metaphase role in both meiosis and mitosis.

O59745	YN29_SCHPO	Putative mannose 6-phosphate receptor-like protein C530.09c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Y375	CIA30_HUMAN	Complex I intermediate-associated protein 30, mitochondrial	11935339	CIA30 complex I assembly factor: a candidate for human complex I deficiency?

P54132	BLM_HUMAN	Bloom syndrome protein	7585968	The Bloom's syndrome gene product is homologous to RecQ helicases.

P0AEJ2	ENTC_ECOLI	Isochorismate synthase entC	2536681	Nucleotide sequence of Escherichia coli isochorismate synthetase gene entC and evolutionary relationship of isochorismate synthetase and other chorismate-utilizing enzymes.

Q08271	GAS4_YEAST	1,3-beta-glucanosyltransferase GAS4	17397106	The Gas family of proteins of Saccharomyces cerevisiae: characterization and evolutionary analysis.

Q03723	OST6_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST6	16297388	Yeast oligosaccharyltransferase consists of two functionally distinct sub-complexes, specified by either the Ost3p or Ost6p subunit.

P25637	YIH1_YEAST	Protein IMPACT homolog	14562095	Global analysis of protein localization in budding yeast.

P0A8P8	XERD_ECOLI	Tyrosine recombinase xerD	8402918	Two related recombinases are required for site-specific recombination at dif and cer in E. coli K12.

P31376	SWC3_YEAST	SWR1-complex protein 3	14562095	Global analysis of protein localization in budding yeast.

O70218	HMX1_MOUSE	Homeobox protein HMX1	9628823	Cloning, characterization, and mapping of the mouse homeobox gene Hmx1.

P25567	SRO9_YEAST	RNA-binding protein SRO9	10564276	Two yeast La motif-containing proteins are RNA-binding proteins that associate with polyribosomes.

O94395	KU70_SCHPO	ATP-dependent DNA helicase II subunit 1	12424244	Telomeric DNA ends are essential for the localization of Ku at telomeres in fission yeast.

O35793	GREM1_RAT	Gremlin-1	15528323	Bone morphogenetic protein antagonists Drm/Gremlin and Dan interact with Slits and act as negative regulators of monocyte chemotaxis.

Q8W1X2	PDXK_ARATH	Pyridoxal kinase	12244454	Cloning and characterization of Arabidopsis thaliana pyridoxal kinase.

O00762	UBE2C_HUMAN	Ubiquitin-conjugating enzyme E2 C	19820702	UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exit.

Q91V36	NRBP2_MOUSE	Nuclear receptor-binding protein 2	18619852	Nuclear receptor binding protein 2 is induced during neural progenitor differentiation and affects cell survival.

Q16520	BATF_HUMAN	Basic leucine zipper transcriptional factor ATF-like	8570175	B-ATF: a novel human bZIP protein that associates with members of the AP-1 transcription factor family.

Q9JLS4	SFRP4_RAT	Secreted frizzled-related protein 4	12063187	Differential expression of secreted frizzled-related protein 4 in decidual cells during pregnancy.

Q10198	NDC80_SCHPO	Kinetochore protein ndc80	11553715	The domain structure of centromeres is conserved from fission yeast to humans.

Q38832	IAA14_ARATH	Auxin-responsive protein IAA14	12036262	Genetics of Aux/IAA and ARF action in plant growth and development.

O00220	TR10A_HUMAN	Tumor necrosis factor receptor superfamily member 10A	18165900	Arf and Rho GAP adapter protein ARAP1 participates in the mobilization of TRAIL-R1/DR4 to the plasma membrane.

Q39254	CAX2_ARATH	Vacuolar cation/proton exchanger 2	8710949	CAX1, an H+/Ca2+ antiporter from Arabidopsis.

O00506	STK25_HUMAN	Serine/threonine-protein kinase 25	15037601	YSK1 is activated by the Golgi matrix protein GM130 and plays a role in cell migration through its substrate 14-3-3zeta.

P25847	MSH2_YEAST	DNA mismatch repair protein MSH2	1334021	Characterization of insertion mutations in the Saccharomyces cerevisiae MSH1 and MSH2 genes: evidence for separate mitochondrial and nuclear functions.

Q9NQS3	PVRL3_HUMAN	Poliovirus receptor-related protein 3	12759359	Recruitment of nectin-3 to cell-cell junctions through trans- heterophilic interaction with CD155, a vitronectin and poliovirus receptor that localizes to alpha(v)beta3 integrin-containing membrane microdomains.

Q7TQA4	TR140_MOUSE	Taste receptor type 2 member 140	12734386	Evolutionary relationships of the Tas2r receptor gene families in mouse and human.

O42968	YB93_SCHPO	Uncharacterized protein C1E8.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P47123	MOG1_YEAST	Nuclear import protein MOG1	9860978	A protein required for nuclear-protein import, Mog1p, directly interacts with GTP-Gsp1p, the Saccharomyces cerevisiae ran homologue.

P77731	ALLA_ECOLI	Ureidoglycolate hydrolase	10601204	Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.

Q9HD42	CHM1A_HUMAN	Charged multivesicular body protein 1a	11559747	CHMP1 is a novel nuclear matrix protein affecting chromatin structure and cell-cycle progression.

Q64434	PTK6_MOUSE	Protein-tyrosine kinase 6	12833144	Altered localization and activity of the intracellular tyrosine kinase BRK/Sik in prostate tumor cells.

Q9NRC8	SIRT7_HUMAN	NAD-dependent deacetylase sirtuin-7	16079181	Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins.

P51686	CCR9_HUMAN	C-C chemokine receptor type 9	10640743	CCR9A and CCR9B: two receptors for the chemokine CCL25/TECK/Ck beta- 15 that differ in their sensitivities to ligand.

Q08003	RFU1_YEAST	Regulator of free ubiquitin chains 1	19410548	An inhibitor of a deubiquitinating enzyme regulates ubiquitin homeostasis.

Q9TU29	GNA15_RABIT	Guanine nucleotide-binding protein subunit alpha-15	10571060	Cloning and characterization of a rabbit ortholog of human Galpha16 and mouse Galpha15.

Q39069	CCB13_ARATH	Cyclin-B1-3	8938409	Modulation of cyclin transcript levels in cultured cells of Arabidopsis thaliana.

Q6V1X1	DPP8_HUMAN	Dipeptidyl peptidase 8	11012666	Cloning, expression and chromosomal localization of a novel human dipeptidyl peptidase (DPP) IV homolog, DPP8.

O15204	ADEC1_HUMAN	ADAM DEC1	9271581	Polymerase chain reaction selects a novel disintegrin proteinase from CD40-activated germinal center dendritic cells.

P50222	MEOX2_HUMAN	Homeobox protein MOX-2	16335786	Characterization of Mesenchyme Homeobox 2 (MEOX2) transcription factor binding to RING finger protein 10.

P22893	TTP_MOUSE	Tristetraprolin	7768935	Phosphorylation of tristetraprolin, a potential zinc finger transcription factor, by mitogen stimulation in intact cells and by mitogen-activated protein kinase in vitro.

Q8C006	TRI35_MOUSE	Tripartite motif-containing protein 35	12692137	Cloning and characterization of a novel RING-B-box-coiled-coil protein with apoptotic function.

P20272	CNR1_RAT	Cannabinoid receptor 1	2165569	Structure of a cannabinoid receptor and functional expression of the cloned cDNA.

Q9PTD7	CING_XENLA	Cingulin	10491082	Xenopus laevis occludin. Identification of in vitro phosphorylation sites by protein kinase CK2 and association with cingulin.

Q8MKK0	OB57A_DROME	General odorant-binding protein 57a	12213773	Genome-wide analysis of the odorant-binding protein gene family in Drosophila melanogaster.

Q9UKF6	CPSF3_HUMAN	Cleavage and polyadenylation specificity factor subunit 3	18688255	Conserved motifs in both CPSF73 and CPSF100 are required to assemble the active endonuclease for histone mRNA 3'-end maturation.

Q13438	OS9_HUMAN	Protein OS-9	18264092	OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD.

P32837	UGA4_YEAST	GABA-specific permease	8455553	Cloning and expression of the UGA4 gene coding for the inducible GABA-specific transport protein of Saccharomyces cerevisiae.

P47739	AL3A1_MOUSE	Aldehyde dehydrogenase, dimeric NADP-preferring	11784860	Structurally normal corneas in aldehyde dehydrogenase 3a1-deficient mice.

Q5EBH1	RASF5_MOUSE	Ras association domain-containing protein 5	9488663	Identification of Nore1 as a potential Ras effector.

Q08446	SGT1_YEAST	Protein SGT1	10445024	SGT1 encodes an essential component of the yeast kinetochore assembly pathway and a novel subunit of the SCF ubiquitin ligase complex.

P83283	IBB2_AMBCE	Bowman-birk type proteinase inhibitor 2	9165081	Purification and primary structure determination of a Bowman-Birk trypsin inhibitor from Torresea cearensis seeds.

Q8MLZ7	IDGF3_DROME	Chitinase-like protein Idgf3	9847235	A new family of growth factors produced by the fat body and active on Drosophila imaginal disc cells.

Q80U70	SUZ12_MOUSE	Polycomb protein Suz12	15385962	Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity.

P15207	ANDR_RAT	Androgen receptor	2341409	A single base mutation in the androgen receptor gene causes androgen insensitivity in the testicular feminized rat.

Q8BGW1	FTO_MOUSE	Alpha-ketoglutarate-dependent dioxygenase FTO	17991826	The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase.

P35498	SCN1A_HUMAN	Sodium channel protein type 1 subunit alpha	10742094	Mutations of SCN1A, encoding a neuronal sodium channel, in two families with GEFS+2.

Q19954	VPS41_CAEEL	Vacuolar protein sorting-associated protein 41 homolog	15837622	Chemical genetics identifies Rab geranylgeranyl transferase as an apoptotic target of farnesyl transferase inhibitors.

O64903	NDK2_ARATH	Nucleoside diphosphate kinase II, chloroplastic	10358052	UV responsive genes of Arabidopsis revealed by similarity to the Gcn4 mediated UV response in yeast.

Q7JXV9	VPS25_DROME	Vacuolar protein-sorting-associated protein 25	16611691	vps25 mosaics display non-autonomous cell survival and overgrowth, and autonomous apoptosis.

Q9LHE5	TO401_ARATH	Mitochondrial import receptor subunit TOM40 homolog 1	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q02883	FMP30_YEAST	N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D, mitochondrial	15878693	Presence and potential signaling function of N-acylethanolamines and their phospholipid precursors in the yeast Saccharomyces cerevisiae.

Q94IA6	C90D1_ARATH	3-epi-6-deoxocathasterone 23-monooxygenase	15703058	CYP90C1 and CYP90D1 are involved in different steps in the brassinosteroid biosynthesis pathway in Arabidopsis thaliana.

Q08548	ALE1_YEAST	Lysophospholipid acyltransferase	17675291	SLC1 and SLC4 encode partially redundant acyl-coenzyme A 1- acylglycerol-3-phosphate O-acyltransferases of budding yeast.

P29033	CXB2_HUMAN	Gap junction beta-2 protein	9139825	Connexin 26 mutations in hereditary non-syndromic sensorineural deafness.

P0AGD1	SODC_ECOLI	Superoxide dismutase [Cu-Zn]	9405149	Unique structural features of the monomeric Cu,Zn superoxide dismutase from Escherichia coli, revealed by X-ray crystallography.

Q14116	IL18_HUMAN	Interleukin-18	8666798	Cloning of the cDNA for human IFN-gamma-inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein.

Q9Y7R6	BIG1_SCHPO	Protein big1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q99759	M3K3_HUMAN	Mitogen-activated protein kinase kinase kinase 3	14743216	A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.

P20226	TBP_HUMAN	TATA-box-binding protein	9748258	Characterization of functional domains of an embryonic stem cell coactivator UTF1 which are conserved and essential for potentiation of ATF-2 activity.

Q8RYD6	AI5L1_ARATH	ABSCISIC ACID-INSENSITIVE 5-like protein 1	15642716	Characterization of three homologous basic leucine zipper transcription factors (bZIP) of the ABI5 family during Arabidopsis thaliana embryo maturation.

Q9LSP8	CMTA6_ARATH	Calmodulin-binding transcription activator 6	12218065	A calmodulin-binding/CGCG box DNA-binding protein family involved in multiple signaling pathways in plants.

P62341	SELT_HUMAN	Selenoprotein T	10567350	New mammalian selenocysteine-containing proteins identified with an algorithm that searches for selenocysteine insertion sequence elements.

Q8L6Y1	UBP14_ARATH	Ubiquitin carboxyl-terminal hydrolase 14	11788751	Diversity of TITAN functions in Arabidopsis seed development.

P77150	PDXY_ECOLI	Pyridoxamine kinase	9537380	Identification and function of the pdxY gene, which encodes a novel pyridoxal kinase involved in the salvage pathway of pyridoxal 5'- phosphate biosynthesis in Escherichia coli K-12.

Q9UKN7	MYO15_HUMAN	Myosin-XV	10552926	Characterization of the human and mouse unconventional myosin XV genes responsible for hereditary deafness DFNB3 and shaker 2.

O43353	RIPK2_HUMAN	Receptor-interacting serine/threonine-protein kinase 2	9642260	RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase.

Q09683	RAD32_SCHPO	DNA repair protein rad32	7885834	Cloning and characterisation of the Schizosaccharomyces pombe rad32 gene: a gene required for repair of double strand breaks and recombination.

Q9VTL1	PCID2_DROME	PCI domain-containing protein 2 homolog	18086857	Definition of global and transcript-specific mRNA export pathways in metazoans.

O13880	VHT1_SCHPO	Vitamin H transporter 1	12557275	Isolation and characterization of the plasma membrane biotin transporter from Schizosaccharomyces pombe.

P84913	CLOT_FARPA	Hemolymph clottable protein	16153866	Purification and partial characterization of the plasma clotting protein from the pink shrimp Farfantepenaeus paulensis.

Q9JKP8	CHRC1_MOUSE	Chromatin accessibility complex protein 1	11000277	Cloning and characterization of the histone-fold proteins YBL1 and YCL1.

Q99497	PARK7_HUMAN	Protein DJ-1	11477070	DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor.

Q9Z0P7	SUFU_MOUSE	Suppressor of fused homolog	11477086	Suppressor of fused negatively regulates beta-catenin signaling.

Q9QXS6	DREB_MOUSE	Drebrin	11991718	A novel, brain-specific mouse drebrin: cDNA cloning, chromosomal mapping, genomic structure, expression, and functional characterization.

P62494	RB11A_RAT	Ras-related protein Rab-11A	1711847	Molecular cloning and characterization of a ras p21-like GTP-binding protein (24KG) from rat liver.

P54731	FAF1_MOUSE	FAS-associated factor 1	8524870	A Fas-associated protein factor, FAF1, potentiates Fas-mediated apoptosis.

O14493	CLD4_HUMAN	Claudin-4	9334247	Clostridium perfringens enterotoxin utilizes two structurally related membrane proteins as functional receptors in vivo.

Q9Y4K3	TRAF6_HUMAN	TNF receptor-associated factor 6	10094049	The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway.

Q14019	COTL1_HUMAN	Coactosin-like protein	11297527	5-lipoxygenase interacts with coactosin-like protein.

P35875	PARP_DROME	Poly [ADP-ribose] polymerase	12183365	The Drosophila heterochromatic gene encoding poly(ADP-ribose) polymerase (PARP) is required to modulate chromatin structure during development.

Q8VCN5	CGL_MOUSE	Cystathionine gamma-lyase	15038791	Murine cystathionine gamma-lyase: complete cDNA and genomic sequences, promoter activity, tissue distribution and developmental expression.

O14216	SLD2_SCHPO	DNA replication regulator sld2	11937031	CDK phosphorylation of Drc1 regulates DNA replication in fission yeast.

P43636	ALG2_YEAST	Alpha-1,3-mannosyltransferase ALG2	15044395	Physical interactions between the Alg1, Alg2, and Alg11 mannosyltransferases of the endoplasmic reticulum.

O74405	SET11_SCHPO	Ribosomal N-lysine methyltransferase set11	18195021	A conserved SET domain methyltransferase, Set11, modifies ribosomal protein Rpl12 in fission yeast.

P36010	NDK_YEAST	Nucleoside diphosphate kinase	12472466	Nucleoside diphosphate kinase of Saccharomyces cerevisiae, Ynk1p: localization to the mitochondrial intermembrane space.

P53108	YIP5_YEAST	Protein YIP5	11943201	Identification of the novel proteins Yip4p and Yip5p as Rab GTPase interacting factors.

Q8BGW5	SOSB2_MOUSE	SOSS complex subunit B2	16533169	NABP1, a novel RORgamma-regulated gene encoding a single-stranded nucleic-acid-binding protein.

Q27869	PIMT_DROME	Protein-L-isoaspartate(D-aspartate) O-methyltransferase	14596598	Catalytic implications from the Drosophila protein L-isoaspartyl methyltransferase structure and site-directed mutagenesis.

Q9Y6Q5	AP1M2_HUMAN	AP-1 complex subunit mu-2	10338135	Mu1B, a novel adaptor medium chain expressed in polarized epithelial cells.

P53039	YIP1_YEAST	Protein transport protein YIP1	11785952	Saccharomyces cerevisiae Pra1p/Yip3p interacts with Yip1p and Rab proteins.

Q12224	RLM1_YEAST	Transcription factor RLM1	9121433	The Saccharomyces cerevisiae MADS-box transcription factor Rlm1 is a target for the Mpk1 mitogen-activated protein kinase pathway.

P17157	PHO85_YEAST	Cyclin-dependent protein kinase PHO85	9032248	A family of cyclin-like proteins that interact with the Pho85 cyclin- dependent kinase.

Q04383	PLM2_YEAST	Protein PLM2	12464632	Complex transcriptional circuitry at the G1/S transition in Saccharomyces cerevisiae.

Q708Y0	EBF2_ARATH	EIN3-binding F-box protein 2	14675533	EIN3-dependent regulation of plant ethylene hormone signaling by two Arabidopsis F box proteins: EBF1 and EBF2.

Q55GD9	VPS25_DICDI	Vacuolar protein-sorting-associated protein 25	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P31385	DEP1_YEAST	Transcriptional regulatory protein DEP1	8056324	Isolation and characterization of a mutant of Saccharomyces cerevisiae with pleiotropic deficiencies in transcriptional activation and repression.

P53261	PESC_YEAST	Pescadillo homolog	12110181	Yph1p, an ORC-interacting protein: potential links between cell proliferation control, DNA replication, and ribosome biogenesis.

Q9SWI1	PKS1_ARATH	Protein PHYTOCHROME KINASE SUBSTRATE 1	10348744	PKS1, a substrate phosphorylated by phytochrome that modulates light signaling in Arabidopsis.

Q8IXM3	RM41_HUMAN	39S ribosomal protein L41, mitochondrial	16024796	Mitochondrial ribosomal protein L41 suppresses cell growth in association with p53 and p27Kip1.

P53992	SC24C_HUMAN	Protein transport protein Sec24C	10214955	Hypothetical protein KIAA0079 is a mammalian homologue of yeast Sec24p.

P15208	INSR_MOUSE	Insulin receptor	9447983	A novel, multifunctional c-Cbl binding protein in insulin receptor signaling in 3T3-L1 adipocytes.

Q9VIQ9	SICK_DROME	Protein sickie	15221030	Functional dissection of an innate immune response by a genome-wide RNAi screen.

Q9JIE6	TSLP_MOUSE	Thymic stromal lymphopoietin	10974033	Molecular cloning and biological characterization of a novel murine lymphoid growth factor.

P0AGD1	SODC_ECOLI	Superoxide dismutase [Cu-Zn]	7786035	Copper, zinc superoxide dismutase in Escherichia coli: periplasmic localization.

Q9Y6J9	TAF6L_HUMAN	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L	9674425	Histone-like TAFs within the PCAF histone acetylase complex.

P40492	FYV10_YEAST	Protein FYV10	12686616	Catabolite degradation of fructose-1,6-bisphosphatase in the yeast Saccharomyces cerevisiae: a genome-wide screen identifies eight novel GID genes and indicates the existence of two degradation pathways.

P25409	ALAT1_RAT	Alanine aminotransferase 1	2043642	Complete amino acid sequence of rat liver cytosolic alanine aminotransferase.

Q86V86	PIM3_HUMAN	Serine/threonine-protein kinase pim-3	18593906	Pim kinases promote cell cycle progression by phosphorylating and down-regulating p27Kip1 at the transcriptional and posttranscriptional levels.

Q5TJ65	VASP_DICDI	Protein VASP homolog	12388544	Requirement of a vasodilator-stimulated phosphoprotein family member for cell adhesion, the formation of filopodia, and chemotaxis in dictyostelium.

O60493	SNX3_HUMAN	Sorting nexin-3	11433298	SNX3 regulates endosomal function through its PX-domain-mediated interaction with PtdIns(3)P.

O15079	SNPH_HUMAN	Syntaphilin	10707983	Syntaphilin: a syntaxin-1 clamp that controls SNARE assembly.

A2BID5	MELT_DANRE	Ventricular zone-expressed PH domain-containing protein	15388229	Identification and characterization of Veph, a novel gene encoding a PH domain-containing protein expressed in the developing central nervous system of vertebrates.

Q96MW5	COG8_HUMAN	Conserved oligomeric Golgi complex subunit 8	11703943	The Sec34/35 Golgi transport complex is related to the exocyst, defining a family of complexes involved in multiple steps of membrane traffic.

Q9HDY5	YK15_SCHPO	Uncharacterized protein PB1A10.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O43451	MGA_HUMAN	Maltase-glucoamylase, intestinal	9446624	Human small intestinal maltase-glucoamylase cDNA cloning. Homology to sucrase-isomaltase.

Q9SRW9	CSLD5_ARATH	Cellulose synthase-like protein D5	17892446	Disruption of ATCSLD5 results in reduced growth, reduced xylan and homogalacturonan synthase activity and altered xylan occurrence in Arabidopsis.

Q9V6K1	TPP2_DROME	Tripeptidyl-peptidase 2	16006508	Molecular architecture and assembly mechanism of Drosophila tripeptidyl peptidase II.

Q06132	SGD1_YEAST	Suppressor of glycerol defect protein 1	11042259	SGD1 encodes an essential nuclear protein of Saccharomyces cerevisiae that affects expression of the GPD1 gene for glycerol 3-phosphate dehydrogenase.

P35268	RL22_HUMAN	60S ribosomal protein L22	8135813	A novel heparin-binding protein, HBp15, is identified as mammalian ribosomal protein L22.

P22062	PIMT_RAT	Protein-L-isoaspartate(D-aspartate) O-methyltransferase	8263531	Tissue-specific expression of isoaspartyl protein carboxyl methyltransferase gene in rat brain and testis.

O14230	FPPS_SCHPO	Farnesyl pyrophosphate synthase	17596513	Geranylgeranyl diphosphate synthase in fission yeast is a heteromer of farnesyl diphosphate synthase (FPS), Fps1, and an FPS-like protein, Spo9, essential for sporulation.

P35580	MYH10_HUMAN	Myosin-10	7782316	Neuronal cell expression of inserted isoforms of vertebrate nonmuscle myosin heavy chain II-B.

P40945	ARF2_DROME	ADP-ribosylation factor 2	8063793	Characterization of class II and class III ADP-ribosylation factor genes and proteins in Drosophila melanogaster.

Q62417	SRBS1_MOUSE	Sorbin and SH3 domain-containing protein 1	9461600	A role for CAP, a novel, multifunctional Src homology 3 domain- containing protein in formation of actin stress fibers and focal adhesions.

O96019	ACL6A_HUMAN	Actin-like protein 6A	10966108	Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis.

P38786	RPP1_YEAST	Ribonuclease P/MRP protein subunit RPP1	9620854	Purification and characterization of the nuclear RNase P holoenzyme complex reveals extensive subunit overlap with RNase MRP.

Q9Y6E0	STK24_HUMAN	Serine/threonine-protein kinase 24	9353338	Cloning and characterization of a human STE20-like protein kinase with unusual cofactor requirements.

Q9LV58	MBF1C_ARATH	Multiprotein-bridging factor 1c	16283071	Transcriptional coactivator MBF1s from Arabidopsis predominantly localize in nucleolus.

Q6NPN4	LYM3_ARATH	LysM domain-containing GPI-anchored protein 2	14517339	Proteomic analysis of glycosylphosphatidylinositol-anchored membrane proteins.

Q3SZX5	RM22_BOVIN	39S ribosomal protein L22, mitochondrial	11551941	The large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present.

Q9P7B3	YI14_SCHPO	Putative cation exchanger C521.04c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q7M3I4	DHI1_RABIT	Corticosteroid 11-beta-dehydrogenase isozyme 1	7836463	Lumenal orientation and post-translational modifications of the liver microsomal 11beta-hydroxysteroid dehydrogenase.

O64629	AUR3_ARATH	Serine/threonine-protein kinase Aurora-3	15722465	Identification and dynamics of two classes of aurora-like kinases in Arabidopsis and other plants.

Q8IN81	FRU_DROME	Sex determination protein fruitless	8978612	Control of male sexual behavior and sexual orientation in Drosophila by the fruitless gene.

Q15831	STK11_HUMAN	Serine/threonine-protein kinase 11	12805220	Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD.

Q9VT28	FRY_DROME	Protein furry	15479641	Control of dendritic branching and tiling by the Tricornered- kinase/Furry signaling pathway in Drosophila sensory neurons.

Q7Z1Z9	CUPG_DICDI	Calcium up-regulated protein G	14871937	The Ca2+/calcineurin-regulated cup gene family in Dictyostelium discoideum and its possible involvement in development.

Q17R60	IMPG1_HUMAN	Interphotoreceptor matrix proteoglycan 1	9691169	Genomic organization and chromosomal localization of the interphotoreceptor matrix proteoglycan-1 (IMPG1) gene: a candidate for 6q-linked retinopathies.

Q8WV44	TRI41_HUMAN	E3 ubiquitin-protein ligase TRIM41	17893151	Amplitude control of protein kinase C by RINCK, a novel E3 ubiquitin ligase.

P55916	UCP3_HUMAN	Mitochondrial uncoupling protein 3	9196039	UCP3: an uncoupling protein homologue expressed preferentially and abundantly in skeletal muscle and brown adipose tissue.

P20081	FKBP_YEAST	FK506-binding protein 1	1996117	Rapamycin sensitivity in Saccharomyces cerevisiae is mediated by a peptidyl-prolyl cis-trans isomerase related to human FK506-binding protein.

A0QWG5	ACYLT_MYCS2	Phosphatidylinositol mannoside acyltransferase	12851411	Identification of the required acyltransferase step in the biosynthesis of the phosphatidylinositol mannosides of mycobacterium species.

Q90XW5	IRX5_XENLA	Iroquois-class homeodomain protein irx-5	18715948	A dual requirement for Iroquois genes during Xenopus kidney development.

P83138	AFP4_MALPA	Antifungal protein 4	11302747	Purification and characterization of three antifungal proteins from cheeseweed (Malva parviflora).

O00292	LFTY2_HUMAN	Left-right determination factor 2	10053005	Characterization and mutation analysis of human LEFTY A and LEFTY B, homologues of murine genes implicated in left-right axis development.

Q12128	BAG7_YEAST	Rho-GTPase-activating protein BAG7	11591390	Functional characterization of the Bag7, Lrg1 and Rgd2 RhoGAP proteins from Saccharomyces cerevisiae.

P80192	M3K9_HUMAN	Mitogen-activated protein kinase kinase kinase 9	8477742	Identification of a new family of human epithelial protein kinases containing two leucine/isoleucine-zipper domains.

Q9UTA4	POPI_SCHPO	Ribonucleases P/MRP protein subunit pop1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O95167	NDUA3_HUMAN	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3	9878551	cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed.

Q80T18	GMFG_RAT	Glia maturation factor gamma	10731725	Cloning of a rat glia maturation factor-gamma (rGMFG) cDNA and expression of its mRNA and protein in rat organs.

P19730	DMPL_PSEUF	Phenol hydroxylase P1 protein	2254258	Complete nucleotide sequence and polypeptide analysis of multicomponent phenol hydroxylase from Pseudomonas sp. strain CF600.

Q12947	FOXF2_HUMAN	Forkhead box protein F2	7957066	Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending.

Q53M11	HS219_ORYSJ	21.9 kDa heat shock protein	19703271	Rice sHsp genes: genomic organization and expression profiling under stress and development.

Q12071	VPS54_YEAST	Vacuolar protein sorting-associated protein 54	10637310	Vps52p, Vps53p, and Vps54p form a novel multisubunit complex required for protein sorting at the yeast late Golgi.

Q9JIZ0	CMLO1_MOUSE	Probable N-acetyltransferase CML1	11397015	Overexpression of camello, a member of a novel protein family, reduces blastomere adhesion and inhibits gastrulation in Xenopus laevis.

Q79PF5	KAIB_SYNE7	Circadian clock protein kaiB	10064581	Physical interactions among circadian clock proteins KaiA, KaiB and KaiC in cyanobacteria.

P35212	CXA4_HUMAN	Gap junction alpha-4 protein	7680674	Molecular cloning and functional expression of human connexin37, an endothelial cell gap junction protein.

Q9SRS9	CHIP_ARATH	E3 ubiquitin-protein ligase CHIP	16640601	AtCHIP functions as an E3 ubiquitin ligase of protein phosphatase 2A subunits and alters plant response to abscisic acid treatment.

P54150	MSRA4_ARATH	Peptide methionine sulfoxide reductase A4, chloroplastic	10806242	Differential regulation of plastidial and cytosolic isoforms of peptide methionine sulfoxide reductase in Arabidopsis.

Q6DE08	AUKBA_XENLA	Serine/threonine-protein kinase 12-A	12221116	Aurora B kinase exists in a complex with survivin and INCENP and its kinase activity is stimulated by survivin binding and phosphorylation.

P26896	IL2RB_RAT	Interleukin-2 receptor subunit beta	1889461	Molecular cloning of cDNAs for the rat interleukin 2 receptor alpha and beta chain genes: differentially regulated gene activity in response to mitogenic stimulation.

Q14993	COJA1_HUMAN	Collagen alpha-1(XIX) chain	1639419	Synteny between the loci for a novel FACIT-like collagen locus (D6S228E) and alpha 1 (IX) collagen (COL9A1) on 6q12-q14 in humans.

Q9Z336	DYLT1_RAT	Dynein light chain Tctex-type 1	9804756	Interaction of Doc2 with tctex-1, a light chain of cytoplasmic dynein. Implication in dynein-dependent vesicle transport.

Q552C6	PYK4_DICDI	Dual specificity protein kinase pyk4	8898113	Classification of tyrosine kinases from Dictyostelium discoideum with two distinct, complete or incomplete catalytic domains.

P55056	APOC4_HUMAN	Apolipoprotein C-IV	8530039	Identification and characterization of a new human gene (APOC4) in the apolipoprotein E, C-I, and C-II gene locus.

O00566	MPP10_HUMAN	U3 small nucleolar ribonucleoprotein protein MPP10	12655004	The human Imp3 and Imp4 proteins form a ternary complex with hMpp10, which only interacts with the U3 snoRNA in 60-80S ribonucleoprotein complexes.

Q6P4R8	NFRKB_HUMAN	Nuclear factor related to kappa-B-binding protein	1777480	Cloning of R kappa B, a novel DNA-binding protein that recognizes the interleukin-2 receptor alpha chain kappa B site.

Q9S7L2	MYB98_ARATH	Transcription factor MYB98	16214903	MYB98 is required for pollen tube guidance and synergid cell differentiation in Arabidopsis.

P13716	HEM2_HUMAN	Delta-aminolevulinic acid dehydratase	2063868	Delta-aminolevulinate dehydratase deficient porphyria: identification of the molecular lesions in a severely affected homozygote.

O14734	ACOT8_HUMAN	Acyl-coenzyme A thioesterase 8	9153233	Binding of HIV-1 Nef to a novel thioesterase enzyme correlates with Nef-mediated CD4 down-regulation.

Q9UK85	DKKL1_HUMAN	Dickkopf-like protein 1	10570958	Functional and structural diversity of the human Dickkopf gene family.

Q8ND56	LS14A_HUMAN	Protein LSM14 homolog A	16484376	RNA-associated protein 55 (RAP55) localizes to mRNA processing bodies and stress granules.

Q8NFU3	TSTD1_HUMAN	Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 1	12817473	Identification and characterization of KAT, a novel gene preferentially expressed in several human cancer cell lines.

Q12072	IOC2_YEAST	ISWI one complex protein 2	12482963	Yeast Isw1p forms two separable complexes in vivo.

Q9BQE5	APOL2_HUMAN	Apolipoprotein L2	11944986	The apolipoprotein L gene cluster has emerged recently in evolution and is expressed in human vascular tissue.

Q9LSQ3	BH082_ARATH	Transcription factor bHLH82	16581911	Transcriptional and posttranscriptional regulation of transcription factor expression in Arabidopsis roots.

O77229	CATA_DICDI	Catalase-A	11004503	Differential developmental expression and cell type specificity of Dictyostelium catalases and their response to oxidative stress and UV- light.

Q9UQ84	EXO1_HUMAN	Exonuclease 1	9685493	Hex1: a new human Rad2 nuclease family member with homology to yeast exonuclease 1.

O43264	ZW10_HUMAN	Centromere/kinetochore protein zw10 homolog	12686595	Zwilch, a new component of the ZW10/ROD complex required for kinetochore functions.

Q04213	IOC4_YEAST	ISWI one complex protein 4	12482963	Yeast Isw1p forms two separable complexes in vivo.

Q8IV48	ERI1_HUMAN	3'-5' exoribonuclease 1	14536070	A 3' exonuclease that specifically interacts with the 3' end of histone mRNA.

Q03265	ATPA_MOUSE	ATP synthase subunit alpha, mitochondrial	7916601	Cloning and functional expression analysis of the alpha subunit of mouse ATP synthase.

O94374	IMA2_SCHPO	Importin subunit alpha-2	12237855	Genome-wide search of Schizosaccharomyces pombe genes causing overexpression-mediated cell cycle defects.

Q9Y614	ACL7B_HUMAN	Actin-like protein 7B	10373328	Cloning, mapping, and expression of two novel actin genes, actin- like-7A (ACTL7A) and actin-like-7B (ACTL7B), from the familial dysautonomia candidate region on 9q31.

Q07540	FRDA_YEAST	Frataxin homolog, mitochondrial	12947415	An interaction between frataxin and Isu1/Nfs1 that is crucial for Fe/S cluster synthesis on Isu1.

P38132	MCM7_YEAST	DNA replication licensing factor MCM7	15023545	Saccharomyces cerevisiae CSM1 gene encoding a protein influencing chromosome segregation in meiosis I interacts with elements of the DNA replication complex.

Q96WV2	YJO2_SCHPO	Uncharacterized PH domain-containing protein PB16A4.02c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q99PI5	LPIN2_MOUSE	Phosphatidate phosphatase LPIN2	19717560	A conserved serine residue is required for the phosphatidate phosphatase activity but not the transcriptional coactivator functions of lipin-1 and lipin-2.

P47031	IML2_YEAST	Mitochondrial outer membrane protein IML2	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P62491	RB11A_HUMAN	Ras-related protein Rab-11A	16905101	Crystal structure of rab11 in complex with rab11 family interacting protein 2.

O42948	YBPD_SCHPO	Uncharacterized WD repeat-containing protein C16H5.13	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q08923	CTI6_YEAST	Histone deacetylase complex subunit CTI6	16286008	Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex.

P39829	GARD_ECOLI	D-galactarate dehydratase	9772162	Evolution of enzymatic activities in the enolase superfamily: characterization of the (D)-glucarate/galactarate catabolic pathway in Escherichia coli.

Q9LJK3	LAG12_ARATH	LAG1 longevity assurance homolog 2	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q9H2C5	O52A5_HUMAN	Olfactory receptor 52A5	11121057	Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.

P20449	DBP5_YEAST	ATP-dependent RNA helicase DBP5	10428971	Dbp5, a DEAD-box protein required for mRNA export, is recruited to the cytoplasmic fibrils of nuclear pore complex via a conserved interaction with CAN/Nup159p.

P27782	LEF1_MOUSE	Lymphoid enhancer-binding factor 1	10498690	Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation.

Q12769	NU160_HUMAN	Nuclear pore complex protein Nup160	11684705	Novel vertebrate nucleoporins Nup133 and Nup160 play a role in mRNA export.

Q07824	TPO1_YEAST	Polyamine transporter 1	9920864	Identification of a gene for a polyamine transport protein in yeast.

Q6IE40	WFD12_RAT	WAP four-disulfide core domain protein 12	15060002	A genomic analysis of rat proteases and protease inhibitors.

Q53RT3	APRV1_HUMAN	Retroviral-like aspartic protease 1	16098038	Identification and characterization of a novel retroviral-like aspartic protease specifically expressed in human epidermis.

Q9WUB7	CLCKA_MOUSE	Chloride channel protein ClC-Ka	11734858	Barttin is a Cl- channel beta-subunit crucial for renal Cl- reabsorption and inner ear K+ secretion.

P86043	PA21B_STRCA	Phospholipase A2	17656163	Ostrich pancreatic phospholipase A(2): purification and biochemical characterization.

O64644	SAP18_ARATH	Histone deacetylase complex subunit SAP18	16429262	AtSAP18, an orthologue of human SAP18, is involved in the regulation of salt stress and mediates transcriptional repression in Arabidopsis.

P50582	HSK1_SCHPO	Cell cycle serine/threonine-protein kinase hsk1	11027263	Schizosaccharomyces pombe Hsk1p is a potential cds1p target required for genome integrity.

Q08682	RSSA1_ARATH	40S ribosomal protein Sa-1	8051176	Arabidopsis p40 homologue. A novel acidic protein associated with the 40 S subunit of ribosomes.

P62627	DLRB1_MOUSE	Dynein light chain roadblock-type 1	14752807	The Roadblock light chains are ubiquitous components of cytoplasmic dynein that form homo- and heterodimers.

Q99942	RNF5_HUMAN	E3 ubiquitin-protein ligase RNF5	12861019	RNF5, a RING finger protein that regulates cell motility by targeting paxillin ubiquitination and altered localization.

P12023	A4_MOUSE	Amyloid beta A4 protein	11517249	C-jun N-terminal kinase (JNK)-interacting protein-1b/islet-brain-1 scaffolds Alzheimer's amyloid precursor protein with JNK.

Q9BZM2	PA2GF_HUMAN	Group IIF secretory phospholipase A2	11112443	Cloning and recombinant expression of human group IIF-secreted phospholipase A(2).

Q949U1	C79F1_ARATH	Dihomomethionine N-hydroxylase	12609033	CYP79F1 and CYP79F2 have distinct functions in the biosynthesis of aliphatic glucosinolates in Arabidopsis.

P70662	LDB1_MOUSE	LIM domain-binding protein 1	9468533	Interactions between LIM domains and the LIM domain-binding protein Ldb1.

Q13115	DUS4_HUMAN	Dual specificity protein phosphatase 4	7535768	Isolation and characterization of a novel dual specific phosphatase, HVH2, which selectively dephosphorylates the mitogen-activated protein kinase.

P24385	CCND1_HUMAN	G1/S-specific cyclin-D1	19412162	F-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damage.

Q53FZ2	ACSM3_HUMAN	Acyl-coenzyme A synthetase ACSM3, mitochondrial	7907320	Human SA gene locus as a candidate locus for essential hypertension.

Q96AE4	FUBP1_HUMAN	Far upstream element-binding protein 1	8125259	A sequence-specific, single-strand binding protein activates the far upstream element of c-myc and defines a new DNA-binding motif.

Q9LMK5	STN1_ARATH	CST complex subunit STN1	19064932	STN1 protects chromosome ends in Arabidopsis thaliana.

Q9USJ7	YJ27_SCHPO	Uncharacterized protein C4B3.07	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

P29555	ABDA_DROME	Homeobox protein abdominal-A	1979297	abdA expression in Drosophila embryos.

P54824	DDX6_XENLA	ATP-dependent RNA helicase ddx6	19458392	Participation of Xenopus Elr-type proteins in vegetal mRNA localization during oogenesis.

Q8I1U7	SMC3_PLAF7	Structural maintenance of chromosomes protein 3 homolog	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

Q9Y243	AKT3_HUMAN	RAC-gamma serine/threonine-protein kinase	20059950	The E3 ligase TTC3 facilitates ubiquitination and degradation of phosphorylated Akt.

Q9VFM9	TWF_DROME	Twinfilin	11724820	Twinfilin is required for actin-dependent developmental processes in Drosophila.

O60142	YNSB_SCHPO	Pentatricopeptide repeat-containing protein C18H10.11c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P19440	GGT1_HUMAN	Gamma-glutamyltranspeptidase 1	2904146	Cloning and nucleotide sequence of human gamma-glutamyl transpeptidase.

P50947	PHO23_YEAST	Transcriptional regulatory protein PHO23	16314178	Stable incorporation of sequence specific repressors Ash1 and Ume6 into the Rpd3L complex.

O04316	NSP4_ARATH	Nitrile-specifier protein 4	18987211	The genetic basis of constitutive and herbivore-induced ESP- independent nitrile formation in Arabidopsis.

O95971	BY55_HUMAN	CD160 antigen	9743336	Cloning of BY55, a novel Ig superfamily member expressed on NK cells, CTL, and intestinal intraepithelial lymphocytes.

Q9H2D1	MFTC_HUMAN	Mitochondrial folate transporter/carrier	10978331	Retrovirally mediated complementation of the glyB phenotype. Cloning of a human gene encoding the carrier for entry of folates into mitochondria.

P18335	ARGD_ECOLI	Acetylornithine/succinyldiaminopimelate aminotransferase	10074354	The dual biosynthetic capability of N-acetylornithine aminotransferase in arginine and lysine biosynthesis.

O54861	SORT_RAT	Sortilin	9452485	Sortilin is the major 110-kDa protein in GLUT4 vesicles from adipocytes.

Q8TCG1	CIP2A_HUMAN	Protein CIP2A	17632056	CIP2A inhibits PP2A in human malignancies.

P52614	FLIK_ECOLI	Flagellar hook-length control protein	8631687	Characterization of the flagellar hook length control protein fliK of Salmonella typhimurium and Escherichia coli.

P0A8I8	RLMH_ECOLI	Ribosomal RNA large subunit methyltransferase H	18755836	Identification of pseudouridine methyltransferase in Escherichia coli.

Q7M3M8	CAS_DROME	Transcription factor castor	1418995	Castor encodes a novel zinc finger protein required for the development of a subset of CNS neurons in Drosophila.

Q8WUM4	PDC6I_HUMAN	Programmed cell death 6-interacting protein	19520058	Penta-EF-hand protein ALG-2 functions as a Ca2+-dependent adaptor that bridges Alix and TSG101.

P53104	ATG1_YEAST	Serine/threonine-protein kinase ATG1	10995454	Tor-mediated induction of autophagy via an Apg1 protein kinase complex.

Q91Z96	BMP2K_MOUSE	BMP-2-inducible protein kinase	11500515	Cloning and characterization of a novel protein kinase that impairs osteoblast differentiation in vitro.

Q12411	MPC70_YEAST	Sporulation-specific protein 21	10899120	Role of the spindle pole body of yeast in mediating assembly of the prospore membrane during meiosis.

P07743	PSP_MOUSE	Parotid secretory protein	2582349	Molecular cloning of mouse PSP mRNA.

Q8WYH8	ING5_HUMAN	Inhibitor of growth protein 5	16387653	ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.

P18899	DDR48_YEAST	Stress protein DDR48	8444852	Purification and characterization of Saccharomyces cerevisiae DNA damage-responsive protein 48 (DDRP 48).

Q9UNK0	STX8_HUMAN	Syntaxin-8	9852078	Three novel proteins of the syntaxin/SNAP-25 family.

P68187	MALK_ECOLI	Maltose/maltodextrin import ATP-binding protein MalK	2026607	Purification and characterization of the membrane-associated components of the maltose transport system from Escherichia coli.

P31209	PABP_SCHPO	Polyadenylate-binding protein, cytoplasmic and nuclear	12112233	Schizosaccharomyces pombe spPABP, a homologue of Saccharomyces cerevisiae Pab1p, is a non-essential, shuttling protein that facilitates mRNA export.

P53350	PLK1_HUMAN	Serine/threonine-protein kinase PLK1	8127874	Induction and down-regulation of PLK, a human serine/threonine kinase expressed in proliferating cells and tumors.

Q92372	RFA1_SCHPO	Replication factor A protein 1	9111307	The Schizosaccharomyces pombe rad11+ gene encodes the large subunit of replication protein A.

P25160	ARL1_DROME	ADP-ribosylation factor-like protein 1	1901655	The arflike gene encodes an essential GTP-binding protein in Drosophila.

Q9P7U2	YI7E_SCHPO	Putative aryl-alcohol dehydrogenase C977.14c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P22146	GAS1_YEAST	1,3-beta-glucanosyltransferase GAS1	1824714	Determinants for glycophospholipid anchoring of the Saccharomyces cerevisiae GAS1 protein to the plasma membrane.

P47930	FOSL2_MOUSE	Fos-related antigen 2	7936655	Cloning and characterisation of the mouse fra-2 gene.

P18168	SERR_DROME	Protein serrate	15829515	The ubiquitin ligase Drosophila Mind bomb promotes Notch signaling by regulating the localization and activity of Serrate and Delta.

P19801	ABP1_HUMAN	Amiloride-sensitive amine oxidase [copper-containing]	8144586	Diamine oxidase is the amiloride-binding protein and is inhibited by amiloride analogues.

Q9FN02	PPP7_ARATH	Serine/threonine-protein phosphatase 7	17238907	Calmodulin-binding protein phosphatase PP7 is involved in thermotolerance in Arabidopsis.

Q9MA41	CTL1_ARATH	Chitinase-like protein 1	10760305	Mutants of Arabidopsis thaliana defective in the acquisition of tolerance to high temperature stress.

P23497	SP100_HUMAN	Nuclear autoantigen Sp-100	11313457	Common properties of nuclear protein SP100 and TIF1alpha chromatin factor: role of SUMO modification.

O94545	KA113_SCHPO	Importin beta-like protein kap113	15116432	Identification of genes encoding putative nucleoporins and transport factors in the fission yeast Schizosaccharomyces pombe: a deletion analysis.

Q96IZ0	PAWR_HUMAN	PRKC apoptosis WT1 regulator protein	8943350	A novel repressor, par-4, modulates transcription and growth suppression functions of the Wilms' tumor suppressor WT1.

Q9ES56	TPPC4_MOUSE	Trafficking protein particle complex subunit 4	11018053	Synbindin, a novel syndecan-2-binding protein in neuronal dendritic spines.

P28838	AMPL_HUMAN	Cytosol aminopeptidase	1908238	Structural and immunological evidence for the identity of prolyl aminopeptidase with leucyl aminopeptidase.

Q9GSX9	RIC8_CAEEL	Synembryn	16162648	Cortical localization of the Galpha protein GPA-16 requires RIC-8 function during C. elegans asymmetric cell division.

Q9NY61	AATF_HUMAN	Protein AATF	14627703	AATF inhibits aberrant production of amyloid beta peptide 1-42 by interacting directly with Par-4.

P28007	GAR1_YEAST	H/ACA ribonucleoprotein complex subunit 1	9843512	Nhp2p and Nop10p are essential for the function of H/ACA snoRNPs.

Q9M3A8	PP273_ARATH	Pentatricopeptide repeat-containing protein At3g49240	15647901	Arabidopsis emb175 and other ppr knockout mutants reveal essential roles for pentatricopeptide repeat (PPR) proteins in plant embryogenesis.

P48987	ATO_DROME	Protein atonal	8196767	Atonal is the proneural gene for Drosophila photoreceptors.

P81066	IRX2_MOUSE	Iroquois-class homeodomain protein IRX-2	17875669	The prepattern transcription factor Irx3 directs nephron segment identity.

P29017	CD1C_HUMAN	T-cell surface glycoprotein CD1c	2447586	Structure and expression of the human thymocyte antigens CD1a, CD1b, and CD1c.

P42124	EZ_DROME	Histone-lysine N-methyltransferase E(z)	11124122	The Drosophila polycomb group proteins ESC and E(Z) are present in a complex containing the histone-binding protein p55 and the histone deacetylase RPD3.

O54874	MRCKA_RAT	Serine/threonine-protein kinase MRCK alpha	9418861	Myotonic dystrophy kinase-related Cdc42-binding kinase acts as a Cdc42 effector in promoting cytoskeletal reorganization.

P05026	AT1B1_HUMAN	Sodium/potassium-transporting ATPase subunit beta-1	2559024	Characterization of two genes for the human Na,K-ATPase beta subunit.

P0A873	TRMD_ECOLI	tRNA (guanine-N(1)-)-methyltransferase	6337136	Purification and characterization of transfer RNA (guanine- 1)methyltransferase from Escherichia coli.

Q9SE97	FH1_ARATH	Formin-like protein 1	10929945	Characterization of the Arabidopsis formin-like protein AFH1 and its interacting protein.

Q9FG72	OPT1_ARATH	Oligopeptide transporter 1	11788749	An oligopeptide transporter gene family in Arabidopsis.

O95406	CNIH_HUMAN	Protein cornichon homolog	10209299	The human homolog of Drosophila cornichon protein is differentially expressed in alloactivated T-cells.

P32744	CLAS2_CAEEL	Protein CLASP-2	12885567	MEI-1/katanin is required for translocation of the meiosis I spindle to the oocyte cortex in C elegans.

Q99MI7	UBA3_RAT	NEDD8-activating enzyme E1 catalytic subunit	11818503	The activating enzyme of NEDD8 inhibits steroid receptor function.

Q02805	ROD1_YEAST	Protein ROD1	8621680	ROD1, a novel gene conferring multiple resistance phenotypes in Saccharomyces cerevisiae.

Q9ZNQ7	RCI2A_ARATH	Hydrophobic protein RCI2A	9342870	Two homologous low-temperature-inducible genes from Arabidopsis encode highly hydrophobic proteins.

Q3KQ35	S17AA_XENLA	Transcription factor Sox-17-alpha-A	19003160	Cephalic hedgehog expression is regulated directly by Sox17 in endoderm development of Xenopus laevis.

Q8IZY2	ABCA7_HUMAN	ATP-binding cassette sub-family A member 7	10873640	Identification of a novel human sterol-sensitive ATP-binding cassette transporter (ABCA7).

P46736	BRCC3_HUMAN	Lys-63-specific deubiquitinase BRCC36	19261749	NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control.

Q9PSN7	VMHT1_CRORU	Hemorrhagic metalloproteinase HT-1	8514736	Primary structures of platelet aggregation inhibitors (disintegrins) autoproteolytically released from snake venom hemorrhagic metalloproteinases and new fluorogenic peptide substrates for these enzymes.

Q9M7X9	CITRX_ARATH	Thioredoxin-like protein CITRX, chloroplastic	20133584	A membrane-associated thioredoxin required for plant growth moves from cell to cell, suggestive of a role in intercellular communication.

O95837	GNA14_HUMAN	Guanine nucleotide-binding protein subunit alpha-14	10191087	Genomic organization of the human G-alpha-14 and G-alpha-Q genes and mutation analysis in chorea-acanthocytosis (CHAC).

P35754	GLRX1_HUMAN	Glutaredoxin-1	7851394	Purification from placenta, amino acid sequence, structure comparisons and cDNA cloning of human glutaredoxin.

Q9FRV4	NAC54_ARATH	Protein CUP-SHAPED COTYLEDON 1	10750709	Involvement of CUP-SHAPED COTYLEDON genes in gynoecium and ovule development in Arabidopsis thaliana.

P49281	NRAM2_HUMAN	Natural resistance-associated macrophage protein 2	17293870	Ca2+ channel blockers reverse iron overload by a new mechanism via divalent metal transporter-1.

Q9NK54	CHIF_DROME	Protein chiffon	10477296	The Drosophila chiffon gene is required for chorion gene amplification, and is related to the yeast Dbf4 regulator of DNA replication and cell cycle.

O59799	YJV1_SCHPO	Coiled-coil-helix-coiled-coil-helix domain-containing protein C550.01c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12438	GLRX6_YEAST	Monothiol glutaredoxin-6	14562095	Global analysis of protein localization in budding yeast.

Q99504	EYA3_HUMAN	Eyes absent homolog 3	19351884	Dephosphorylation of the C-terminal tyrosyl residue of the DNA damage-related histone H2A.X is mediated by the protein phosphatase eyes absent.

Q9NWF9	RN216_HUMAN	E3 ubiquitin-protein ligase RNF216	15367624	Ring finger protein ZIN interacts with human immunodeficiency virus type 1 Vif.

P48740	MASP1_HUMAN	Mannan-binding lectin serine protease 1	17182967	Cooperation between MASP-1 and MASP-2 in the generation of C3 convertase through the MBL pathway.

Q9WV48	SHAN1_RAT	SH3 and multiple ankyrin repeat domains protein 1	11178875	Sharpin, a novel postsynaptic density protein that directly interacts with the shank family of proteins.

P12815	PDCD6_MOUSE	Programmed cell death protein 6	8560270	Interfering with apoptosis: Ca(2+)-binding protein ALG-2 and Alzheimer's disease gene ALG-3.

P35568	IRS1_HUMAN	Insulin receptor substrate 1	8513971	Human skeletal muscle insulin receptor substrate-1. Characterization of the cDNA, gene, and chromosomal localization.

Q08287	NOP8_YEAST	60S ribosome subunit biogenesis protein NOP8	9891085	Nip7p interacts with Nop8p, an essential nucleolar protein required for 60S ribosome biogenesis, and the exosome subunit Rrp43p.

O13829	RU17_SCHPO	U1 small nuclear ribonucleoprotein 70 kDa homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P54841	MAFB_MOUSE	Transcription factor MafB	14513037	MafB deficiency causes defective respiratory rhythmogenesis and fatal central apnea at birth.

Q9BYE0	HES7_HUMAN	Transcription factor HES-7	11260262	Hes7: a bHLH-type repressor gene regulated by Notch and expressed in the presomitic mesoderm.

O24585	CRI4_MAIZE	Putative receptor protein kinase CRINKLY4	18539132	Dimerization properties of the transmembrane domains of Arabidopsis CRINKLY4 receptor-like kinase and homologs.

Q90WP7	PLR_RANPI	Peptide leucine arginine	14636071	Ranacyclins, a new family of short cyclic antimicrobial peptides: biological function, mode of action and parameters involved in target specificity.

Q91V87	FGRL1_MOUSE	Fibroblast growth factor receptor-like 1	11418238	Identification of a new fibroblast growth factor receptor, FGFR5.

Q08605	GAGA_DROME	Transcription factor GAGA	7504178	Isolation of cDNAs encoding the Drosophila GAGA transcription factor.

Q9ZU52	ALFC3_ARATH	Probable fructose-bisphosphate aldolase 3, chloroplastic	12492832	The impact of oxidative stress on Arabidopsis mitochondria.

Q96EZ8	MCRS1_HUMAN	Microspherule protein 1	9765390	Herpes simplex virus 1 regulatory protein ICP22 interacts with a new cell cycle-regulated factor and accumulates in a cell cycle-dependent fashion in infected cells.

Q9XTF3	MBK2_CAEEL	Dual specificity tyrosine-phosphorylation-regulated kinase mbk-2	17869113	Regulation of MBK-2/Dyrk kinase by dynamic cortical anchoring during the oocyte-to-zygote transition.

O94329	PSF2_SCHPO	DNA replication complex GINS protein psf2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O08564	LPP1_RAT	Lipid phosphate phosphohydrolase 1	11704545	Molecular cloning and expression of pulmonary lipid phosphate phosphohydrolases.

Q54JH6	CMT1_DICDI	DNA (cytosine-5)-methyltransferase	16282589	Silencing of retrotransposons in Dictyostelium by DNA methylation and RNAi.

O15205	UBD_HUMAN	Ubiquitin D	19028597	Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system.

Q43309	1A14_ARATH	1-aminocyclopropane-1-carboxylate synthase 4	12968022	Biochemical diversity among the 1-amino-cyclopropane-1-carboxylate synthase isozymes encoded by the Arabidopsis gene family.

P01768	HV307_HUMAN	Ig heavy chain V-III region CAM	6774332	Amino acid sequence of the variable region of a human mu chain: location of a possible JH segment.

O60906	NSMA_HUMAN	Sphingomyelin phosphodiesterase 2	9520418	Cloned mammalian neutral sphingomyelinase: functions in sphingolipid signaling?

P97863	NFIB_MOUSE	Nuclear factor 1 B-type	9056636	Expression patterns of the four nuclear factor I genes during mouse embryogenesis indicate a potential role in development.

Q9GZX7	AICDA_HUMAN	Activation-induced cytidine deaminase	11007475	Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2).

Q6P6Q2	K2C5_RAT	Keratin, type II cytoskeletal 5	14551252	Acroplaxome, an F-actin-keratin-containing plate, anchors the acrosome to the nucleus during shaping of the spermatid head.

Q923E4	SIRT1_MOUSE	NAD-dependent deacetylase sirtuin-1	11672522	Negative control of p53 by Sir2alpha promotes cell survival under stress.

Q8S895	SAT2_ARATH	Serine acetyltransferase 2	15579666	Characterization and expression analysis of a serine acetyltransferase gene family involved in a key step of the sulfur assimilation pathway in Arabidopsis.

Q9QWE9	GGT5_RAT	Gamma-glutamyltransferase 5	9374738	Expression and regulation of gamma-glutamyl transpeptidase-related enzyme in tracheal cells.

Q1AGV6	SDC4B_XENLA	Syndecan 4-B	16604063	Syndecan-4 regulates non-canonical Wnt signalling and is essential for convergent and extension movements in Xenopus embryos.

Q5FWY4	MCM6M_XENLA	Maternal DNA replication licensing factor mcm6	16369567	The ATPase activity of MCM2-7 is dispensable for pre-RC assembly but is required for DNA unwinding.

Q8WV16	DCAF4_HUMAN	DDB1- and CUL4-associated factor 4	16949367	A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1.

P32942	ICAM3_HUMAN	Intercellular adhesion molecule 3	8459213	Cloning and expression of intercellular adhesion molecule 3 reveals strong homology to other immunoglobulin family counter-receptors for lymphocyte function-associated antigen 1.

O75380	NDUS6_HUMAN	NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial	9647766	cDNA sequence and chromosomal localization of the remaining three human nuclear encoded iron sulphur protein (IP) subunits of complex I: the human IP fraction is completed.

Q8CGZ2	ADIP_RAT	Afadin- and alpha-actinin-binding protein	12446711	ADIP, a novel afadin- and alpha-actinin-binding protein localized at cell-cell adherens junctions.

O55225	OTOGL_MOUSE	Otogelin	9405633	Otogelin: a glycoprotein specific to the acellular membranes of the inner ear.

Q9H293	IL25_HUMAN	Interleukin-25	11058597	IL-17E, a novel proinflammatory ligand for the IL-17 receptor homolog IL-17Rh1.

Q9Y3D6	FIS1_HUMAN	Mitochondrial fission 1 protein	16107562	A role for Fis1 in both mitochondrial and peroxisomal fission in mammalian cells.

Q8IZP0	ABI1_HUMAN	Abl interactor 1	11418237	Isolation of hNap1BP which interacts with human Nap 1 (NCKAP1) whose expression is down-regulated in Alzheimer's disease.

P70056	FOXH1_XENLA	Forkhead box protein H1	12050132	A novel Xenopus Smad-interacting forkhead transcription factor (XFast-3) cooperates with XFast-1 in regulating gastrulation movements.

Q969G9	NKD1_HUMAN	Protein naked cuticle homolog 1	15687260	PR72, a novel regulator of Wnt signaling required for Naked cuticle function.

P81449	ATPJ_YEAST	ATP synthase subunit e, mitochondrial	9271204	Yeast mitochondrial F1F0-ATPase: the novel subunit e is identical to Tim11.

P48598	IF4E_DROME	Eukaryotic translation initiation factor 4E	9065696	Localization, structure and expression of the gene for translation initiation factor eIF-4E from Drosophila melanogaster.

Q15661	TRYB1_HUMAN	Tryptase beta-1	2187193	Human mast cell tryptase: multiple cDNAs and genes reveal a multigene serine protease family.

P36615	CSK1_SCHPO	Serine/threonine-protein kinase csk1	8467814	Characterization of the fission yeast mcs2 cyclin and its associated protein kinase activity.

Q9FHW7	SKP1B_ARATH	SKP1-like protein 1B	19682297	An F-box gene, CPR30, functions as a negative regulator of the defense response in Arabidopsis.

Q9P0L9	PK2L1_HUMAN	Polycystic kidney disease 2-like 1 protein	9878261	Identification of PKD2L, a human PKD2-related gene: tissue-specific expression and mapping to chromosome 10q25.

O43768	ENSA_HUMAN	Alpha-endosulfine	9653196	Human alpha-endosulfine, a possible regulator of sulfonylurea- sensitive K(ATP) channel: molecular cloning, expression and biological properties.

Q99081	HTF4_HUMAN	Transcription factor 12	1312219	HEB, a helix-loop-helix protein related to E2A and ITF2 that can modulate the DNA-binding ability of myogenic regulatory factors.

O04983	ACCC_ARATH	Biotin carboxylase, chloroplastic	12938931	Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis.

P47134	BIR1_YEAST	Protein BIR1	10557299	Participation of Bir1p, a member of the inhibitor of apoptosis family, in yeast chromosome segregation events.

Q24459	PCL_DROME	Polycomb protein Pcl	11571280	Polycomblike PHD fingers mediate conserved interaction with enhancer of zeste protein.

P42898	MTHR_HUMAN	Methylenetetrahydrofolate reductase	7726158	Seven novel mutations in the methylenetetrahydrofolate reductase gene and genotype/phenotype correlations in severe methylenetetrahydrofolate reductase deficiency.

Q06580	MLC2_YEAST	Myosin light chain 2	15210731	Identification and functional analysis of the essential and regulatory light chains of the only type II myosin Myo1p in Saccharomyces cerevisiae.

Q9UBC3	DNM3B_HUMAN	DNA (cytosine-5)-methyltransferase 3B	10555141	DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development.

Q9Y5Y7	LYVE1_HUMAN	Lymphatic vessel endothelial hyaluronic acid receptor 1	10037799	LYVE-1, a new homologue of the CD44 glycoprotein is a lymph-specific receptor for hyaluronan.

Q9VFG8	KIBRA_DROME	Protein kibra	20159599	Kibra Is a regulator of the Salvador/Warts/Hippo signaling network.

Q9VNS0	MAEL_DROME	Protein maelstrom	19758565	Drosophila maelstrom ensures proper germline stem cell lineage differentiation by repressing microRNA-7.

Q9NZ50	SYUG_BOVIN	Gamma-synuclein	10192768	Synoretin: a new protein belonging to the synuclein family.

P17423	KHSE_YEAST	Homoserine kinase	2165904	Yeast homoserine kinase. Characteristics of the corresponding gene, THR1, and the purified enzyme, and evolutionary relationships with other enzymes of threonine metabolism.

O35458	VIAAT_RAT	Vesicular inhibitory amino acid transporter	12031963	Expression of the vesicular inhibitory amino acid transporter in pancreatic islet cells: distribution of the transporter within rat islets.

P10620	MGST1_HUMAN	Microsomal glutathione S-transferase 1	3372534	Gene expression of rat and human microsomal glutathione S- transferases.

P13284	GILT_HUMAN	Gamma-interferon-inducible lysosomal thiol reductase	3136170	Molecular and biochemical characterization of a novel gamma- interferon-inducible protein.

Q96IK0	TM101_HUMAN	Transmembrane protein 101	12761501	Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.

P17252	KPCA_HUMAN	Protein kinase C alpha type	17893151	Amplitude control of protein kinase C by RINCK, a novel E3 ubiquitin ligase.

Q21921	SIRT1_CAEEL	NAD-dependent deacetylase SIR2 homolog	16777605	C. elegans SIR-2.1 interacts with 14-3-3 proteins to activate DAF-16 and extend life span.

O74370	ISY1_SCHPO	Pre-mRNA-splicing factor isy1	11884590	Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

Q6IRE4	TS101_RAT	Tumor susceptibility gene 101 protein	14761944	TSG101 interacts with apoptosis-antagonizing transcription factor and enhances androgen receptor-mediated transcription by promoting its monoubiquitination.

P58446	VARA_VIOAR	Varv peptide A	12477048	Cyclotides: a novel type of cytotoxic agents.

Q01320	TOP2A_MOUSE	DNA topoisomerase 2-alpha	1331984	Characterization of cDNA encoding the mouse DNA topoisomerase II that can complement the budding yeast top2 mutation.

Q553Y1	P2XB_DICDI	P2X receptor B	19833731	Functional characterization of intracellular Dictyostelium discoideum P2X receptors.

P19109	DDX17_DROME	ATP-dependent RNA helicase p62	12368261	A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins.

Q09511	RSP4_CAEEL	Probable splicing factor, arginine/serine-rich 4	10906451	Unique and redundant functions of SR proteins, a conserved family of splicing factors, in Caenorhabditis elegans development.

Q96CS3	FAF2_HUMAN	FAS-associated factor 2	19818707	The otubain YOD1 is a deubiquitinating enzyme that associates with p97 to facilitate protein dislocation from the ER.

Q7SXL3	TBP_DANRE	TATA-box-binding protein	11250159	TBP is not universally required for zygotic RNA polymerase II transcription in zebrafish.

P22234	PUR6_HUMAN	Multifunctional protein ADE2	2253271	Cloning and sequencing of a human cDNA coding for a multifunctional polypeptide of the purine pathway by complementation of the ade2-101 mutant in Saccharomyces cerevisiae.

P11240	COX5A_RAT	Cytochrome c oxidase subunit 5A, mitochondrial	2544858	Nucleotide sequence of cDNA encoding subunit Va from rat heart cytochrome c oxidase.

Q04592	PCSK5_MOUSE	Proprotein convertase subtilisin/kexin type 5	8947550	The isoforms of proprotein convertase PC5 are sorted to different subcellular compartments.

P06681	CO2_HUMAN	Complement C2	8621452	Type II human complement C2 deficiency. Allele-specific amino acid substitutions (Ser189 --> Phe; Gly444 --> Arg) cause impaired C2 secretion.

Q9NRZ5	PLCD_HUMAN	1-acyl-sn-glycerol-3-phosphate acyltransferase delta	11487472	The structure and functions of human lysophosphatidic acid acyltransferases.

Q15542	TAF5_HUMAN	Transcription initiation factor TFIID subunit 5	10373431	Identification of TATA-binding protein-free TAFII-containing complex subunits suggests a role in nucleosome acetylation and signal transduction.

P41318	LST8_YEAST	Target of rapamycin complex subunit LST8	12719473	LST8 negatively regulates amino acid biosynthesis as a component of the TOR pathway.

P41238	ABEC1_HUMAN	C->U-editing enzyme APOBEC-1	8078915	Dimeric structure of a human apolipoprotein B mRNA editing protein and cloning and chromosomal localization of its gene.

Q64705	USF2_MOUSE	Upstream stimulatory factor 2	7523363	Archaic structure of the gene encoding transcription factor USF.

P46667	ATHB5_ARATH	Homeobox-leucine zipper protein ATHB-5	11247607	DNA-binding and dimerization preferences of Arabidopsis homeodomain- leucine zipper transcription factors in vitro.

O43908	NKG2F_HUMAN	NKG2-F type II integral membrane protein	9683661	The genomic organization of NKG2C, E, F, and D receptor genes in the human natural killer gene complex.

P30620	PSO2_YEAST	DNA cross-link repair protein PSO2/SNM1	15590324	The yeast Snm1 protein is a DNA 5'-exonuclease.

O00423	EMAL1_HUMAN	Echinoderm microtubule-associated protein-like 1	9226380	Isolation of a novel human homologue of the gene coding for echinoderm microtubule-associated protein (EMAP) from the Usher syndrome type 1a locus at 14q32.

O15259	NPHP1_HUMAN	Nephrocystin-1	12872122	Mutations in a novel gene, NPHP3, cause adolescent nephronophthisis, tapeto-retinal degeneration and hepatic fibrosis.

O04567	Y1719_ARATH	Probable inactive receptor kinase At1g27190	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

P01569	IFNA5_HUMAN	Interferon alpha-5	6163083	The structure of eight distinct cloned human leukocyte interferon cDNAs.

Q9NP59	S40A1_HUMAN	Solute carrier family 40 member 1	10693807	Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter.

Q12103	YD109_YEAST	Putative lipase YDL109C	10341423	Systematic analysis of yeast strains with possible defects in lipid metabolism.

Q12153	SSF2_YEAST	Ribosome biogenesis protein SSF2	12702244	Functional analysis in yeast of the Brix protein superfamily involved in the biogenesis of ribosomes.

Q9V4Z9	LINES_DROME	Protein lines	9477325	The lines gene of Drosophila is required for specific functions of the Abdominal-B HOX protein.

Q92565	RPGF5_HUMAN	Rap guanine nucleotide exchange factor 5	10934204	Identification of guanine nucleotide exchange factors (GEFs) for the Rap1 GTPase. Regulation of MR-GEF by M-Ras-GTP interaction.

O43557	TNF14_HUMAN	Tumor necrosis factor ligand superfamily member 14	9765287	Herpesvirus entry mediator ligand (HVEM-L), a novel ligand for HVEM/TR2, stimulates proliferation of T cells and inhibits HT29 cell growth.

P25374	NFS1_YEAST	Cysteine desulfurase, mitochondrial	10551871	Yeast mitochondrial protein, Nfs1p, coordinately regulates iron- sulfur cluster proteins, cellular iron uptake, and iron distribution.

Q9VS24	MELT_DROME	Protein melted	16143107	The growth regulators warts/lats and melted interact in a bistable loop to specify opposite fates in Drosophila R8 photoreceptors.

Q91619	NODAL_XENLA	Nodal homolog	16959238	Anteriorward shifting of asymmetric Xnr1 expression and contralateral communication in left-right specification in Xenopus.

Q96BI1	S22AI_HUMAN	Solute carrier family 22 member 18	16314844	Tumor suppressor candidate TSSC5 is regulated by UbcH6 and a novel ubiquitin ligase RING105.

P69771	DID2_YEAST	Vacuolar protein-sorting-associated protein 46	17130288	Did2 coordinates Vps4-mediated dissociation of ESCRT-III from endosomes.

Q9R1A3	NET3_MOUSE	Netrin-3	10381568	Divergent properties of mouse netrins.

Q15916	ZBTB6_HUMAN	Zinc finger and BTB domain-containing protein 6	7958847	The POZ domain: a conserved protein-protein interaction motif.

Q9XIC7	SERK2_ARATH	Somatic embryogenesis receptor kinase 2	18667726	Arabidopsis SOMATIC EMBRYOGENESIS RECEPTOR KINASE proteins serve brassinosteroid-dependent and -independent signaling pathways.

Q24318	TFDP_DROME	Transcription factor Dp	9271122	Mutations in Drosophila DP and E2F distinguish G1-S progression from an associated transcriptional program.

Q13144	EI2BE_HUMAN	Translation initiation factor eIF-2B subunit epsilon	8688466	Cloning and characterization of cDNAs encoding the epsilon-subunit of eukaryotic initiation factor-2B from rabbit and human.

Q9SIM9	ORE9_ARATH	F-box protein ORE9	16546078	The Arabidopsis MAX pathway controls shoot branching by regulating auxin transport.

P53951	COG5_YEAST	Conserved oligomeric Golgi complex subunit 5	11703943	The Sec34/35 Golgi transport complex is related to the exocyst, defining a family of complexes involved in multiple steps of membrane traffic.

Q9US35	DSD1_SCHPO	D-serine dehydratase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8C0N2	GPAT3_MOUSE	Glycerol-3-phosphate acyltransferase 3	17170135	Molecular identification of microsomal acyl-CoA:glycerol-3-phosphate acyltransferase, a key enzyme in de novo triacylglycerol synthesis.

P54886	P5CS_HUMAN	Delta-1-pyrroline-5-carboxylate synthase	8761662	Database cloning human delta 1-pyrroline-5-carboxylate synthetase (P5CS) cDNA: a bifunctional enzyme catalyzing the first 2 steps in proline biosynthesis.

P25801	RBTN2_MOUSE	Rhombotin-2	9391090	The LIM-domain binding protein Ldb1 and its partner LMO2 act as negative regulators of erythroid differentiation.

Q8R511	FNBP1_RAT	Formin-binding protein 1	12244061	Rapostlin is a novel effector of Rnd2 GTPase inducing neurite branching.

Q60803	TRAF3_MOUSE	TNF receptor-associated factor 3	18849341	FLN29 deficiency reveals its negative regulatory role in the Toll- like receptor (TLR) and retinoic acid-inducible gene I (RIG-I)-like helicase signaling pathway.

Q03048	COFI_YEAST	Cofilin	10231390	Cooperation of two actin-binding proteins, cofilin and Aip1, in Saccharomyces cerevisiae.

Q03497	STE20_YEAST	Serine/threonine-protein kinase STE20	11940652	Cdc42 regulation of kinase activity and signaling by the yeast p21- activated kinase Ste20.

O43464	HTRA2_HUMAN	Serine protease HTRA2, mitochondrial	19502560	THAP5 is a human cardiac-specific inhibitor of cell cycle that is cleaved by the proapoptotic Omi/HtrA2 protease during cell death.

Q23TC2	TTL3A_TETTH	Tubulin glycylase 3A	19531357	TTLL3 Is a tubulin glycine ligase that regulates the assembly of cilia.

P07834	CDC4_YEAST	Cell division control protein 4	9346239	A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p.

O75934	SPF27_HUMAN	Pre-mRNA-splicing factor SPF27	12169396	Amplification of the BCAS2 gene at chromosome 1p13.3-21 in human primary breast cancer.

P12104	FABPI_HUMAN	Fatty acid-binding protein, intestinal	2824476	The human and rodent intestinal fatty acid binding protein genes. A comparative analysis of their structure, expression, and linkage relationships.

P15315	CUP2_YEAST	Transcriptional activator protein CUP2	2651899	A cysteine-rich nuclear protein activates yeast metallothionein gene transcription.

P53130	GPG1_YEAST	Heterotrimeric G protein gamma subunit GPG1	12150916	The Galpha protein Gpa2 controls yeast differentiation by interacting with kelch repeat proteins that mimic Gbeta subunits.

Q17390	CUL2_CAEEL	Cullin-2	17304241	The Caenorhabditis elegans cell-cycle regulator ZYG-11 defines a conserved family of CUL-2 complex components.

O80763	NRX1_ARATH	Probable nucleoredoxin 1	19714218	Penetration of the stigma and style elicits a novel transcriptome in pollen tubes, pointing to genes critical for growth in a pistil.

P02458	CO2A1_HUMAN	Collagen alpha-1(II) chain	2587267	Nucleotide sequence of the full length cDNA encoding for human type II procollagen.

P48524	BUL1_YEAST	Ubiquitin ligase-binding protein BUL1	11352928	Components of a ubiquitin ligase complex specify polyubiquitination and intracellular trafficking of the general amino acid permease.

P67826	CUTC_ECOLI	Copper homeostasis protein cutC	7635807	Identification of cutC and cutF (nlpE) genes involved in copper tolerance in Escherichia coli.

P32266	MGM1_YEAST	Dynamin-like GTPase MGM1, mitochondrial	15087460	Ugo1p links the Fzo1p and Mgm1p GTPases for mitochondrial fusion.

Q9H000	MKRN2_HUMAN	Probable E3 ubiquitin-protein ligase makorin-2	11597136	Phylogenetic conservation of the makorin-2 gene, encoding a multiple zinc-finger protein, antisense to the raf1 proto-oncogene.

Q32MD9	CDON_MOUSE	Cell adhesion molecule-related/down-regulated by oncogenes	15520228	Netrins and neogenin promote myotube formation.

O04719	P2C77_ARATH	Protein phosphatase 2C 77	16571665	Fibrillin expression is regulated by abscisic acid response regulators and is involved in abscisic acid-mediated photoprotection.

O75822	EIF3J_HUMAN	Eukaryotic translation initiation factor 3 subunit J	17322308	Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry.

Q92832	NELL1_HUMAN	Protein kinase C-binding protein NELL1	8975702	Cloning and characterization of two novel human cDNAs (NELL1 and NELL2) encoding proteins with six EGF-like repeats.

Q9V5M3	LOLA6_DROME	Longitudinals lacking protein, isoforms N/O/W/X/Y	11880341	Lola regulates midline crossing of CNS axons in Drosophila.

Q9H2B4	S26A1_HUMAN	Sulfate anion transporter 1	11087667	Mapping of five new putative anion transporter genes in human and characterization of SLC26A6, a candidate gene for pancreatic anion exchanger.

Q96LA8	ANM6_HUMAN	Protein arginine N-methyltransferase 6	16157300	Protein arginine methyltransferase 6 specifically methylates the nonhistone chromatin protein HMGA1a.

Q07912	ACK1_HUMAN	Activated CDC42 kinase 1	10360579	Structure of the small G protein Cdc42 bound to the GTPase-binding domain of ACK.

P61224	RAP1B_HUMAN	Ras-related protein Rap-1b	18309292	The Rap-RapGAP complex: GTP hydrolysis without catalytic glutamine and arginine residues.

Q80YF9	RHG33_MOUSE	Rho GTPase-activating protein 33	12773384	TCGAP, a multidomain Rho GTPase-activating protein involved in insulin-stimulated glucose transport.

O35314	SCG1_RAT	Secretogranin-1	2641278	Nucleotide sequence and cellular distribution of rat chromogranin B (secretogranin I) mRNA in the neuroendocrine system.

P18161	PYK2_DICDI	Dual specificity protein kinase pyk2	1972546	Developmentally regulated protein-tyrosine kinase genes in Dictyostelium discoideum.

P39742	SEC72_YEAST	Translocation protein SEC72	8051213	Sec72p contributes to the selective recognition of signal peptides by the secretory polypeptide translocation complex.

O00198	HRK_HUMAN	Activator of apoptosis harakiri	9130713	Harakiri, a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-X(L).

Q99954	SMR3A_HUMAN	Submaxillary gland androgen-regulated protein 3A	9354371	Nucleotide sequence of gene PBI encoding a protein homologous to salivary proline-rich protein P-B.

Q8CBD1	NRIP1_MOUSE	Nuclear receptor-interacting protein 1	11006275	Receptor-interacting protein 140 directly recruits histone deacetylases for gene silencing.

O55131	SEPT7_MOUSE	Septin-7	11739749	The septin CDCrel-1 is dispensable for normal development and neurotransmitter release.

Q9CAG3	LOX6_ARATH	Lipoxygenase 6, choloroplastic	15028209	The Arabidopsis thaliana chloroplast proteome reveals pathway abundance and novel protein functions.

Q9Z132	RSPO1_MOUSE	R-spondin-1	14732490	R-spondin, a novel gene with thrombospondin type 1 domain, was expressed in the dorsal neural tube and affected in Wnts mutants.

Q05513	KPCZ_HUMAN	Protein kinase C zeta type	11755531	p62 forms a ternary complex with PKCzeta and PAR-4 and antagonizes PAR-4-induced PKCzeta inhibition.

P36973	APT2_YEAST	Adenine phosphoribosyltransferase 2	9864350	APT1, but not APT2, codes for a functional adenine phosphoribosyltransferase in Saccharomyces cerevisiae.

O49621	MLO1_ARATH	MLO-like protein 1	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q9UKN8	TF3C4_HUMAN	General transcription factor 3C polypeptide 4	10523658	The TFIIIC90 subunit of TFIIIC interacts with multiple components of the RNA polymerase III machinery and contains a histone-specific acetyltransferase activity.

Q01532	BLH1_YEAST	Cysteine proteinase 1, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

Q00649	HSPB1_CHICK	Heat shock protein beta-1	2071672	A 25-kD inhibitor of actin polymerization is a low molecular mass heat shock protein.

P39007	STT3_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3	16297388	Yeast oligosaccharyltransferase consists of two functionally distinct sub-complexes, specified by either the Ost3p or Ost6p subunit.

P28715	ERCC5_HUMAN	DNA repair protein complementing XP-G cells	7510366	An ERCC5 gene with homology to yeast RAD2 is involved in group G Xeroderma pigmentosum.

P53705	BUD4_CANAL	Bud site selection protein BUD4	9478896	Linkage of adhesion, filamentous growth, and virulence in Candida albicans to a single gene, INT1.

Q24212	STNB_DROME	Protein stoned-B	10407025	The stoned proteins regulate synaptic vesicle recycling in the presynaptic terminal.

O95817	BAG3_HUMAN	BAG family molecular chaperone regulator 3	10597216	Bis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell death.

O95831	AIFM1_HUMAN	Apoptosis-inducing factor 1, mitochondrial	9989411	Molecular characterization of mitochondrial apoptosis-inducing factor.

Q05586	NMDZ1_HUMAN	Glutamate [NMDA] receptor subunit zeta-1	7679115	Molecular cloning and chromosomal localization of the key subunit of the human N-methyl-D-aspartate receptor.

P38398	BRCA1_HUMAN	Breast cancer type 1 susceptibility protein	17525332	ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

Q9NPC1	LT4R2_HUMAN	Leukotriene B4 receptor 2	10913346	Cloning and characterization of cDNA encoding a novel human leukotriene B4 receptor.

Q38906	TOC34_ARATH	Translocase of chloroplast 34, chloroplastic	15028209	The Arabidopsis thaliana chloroplast proteome reveals pathway abundance and novel protein functions.

Q8K4K7	ABRA_RAT	Actin-binding Rho-activating protein	11983702	STARS, a striated muscle activator of Rho signaling and serum response factor-dependent transcription.

P53102	MND1_YEAST	Meiotic nuclear division protein 1	15249670	Heterodimeric complexes of Hop2 and Mnd1 function with Dmc1 to promote meiotic homolog juxtaposition and strand assimilation.

Q9NYL2	MLTK_HUMAN	Mitogen-activated protein kinase kinase kinase MLT	12761180	Regulation of a mitogen-activated protein kinase kinase kinase, MLTK by PKN.

Q9UHF3	NAT8B_HUMAN	Probable N-acetyltransferase 8B	11397015	Overexpression of camello, a member of a novel protein family, reduces blastomere adhesion and inhibits gastrulation in Xenopus laevis.

Q9FN69	GL3_ARATH	Transcription factor GLABRA 3	14627722	The bHLH genes GLABRA3 (GL3) and ENHANCER OF GLABRA3 (EGL3) specify epidermal cell fate in the Arabidopsis root.

P52627	FLIZ_ECOLI	Regulator of sigma S factor FliZ	18765794	Inverse regulatory coordination of motility and curli-mediated adhesion in Escherichia coli.

Q79PF6	KAIA_SYNE7	Circadian clock protein kaiA	11356188	Two KaiA-binding domains of cyanobacterial circadian clock protein KaiC.

Q04636	POB3_YEAST	FACT complex subunit POB3	9705338	Characterization of the CP complex, an abundant dimer of Cdc68 and Pob3 proteins that regulates yeast transcriptional activation and chromatin repression.

Q9VS24	MELT_DROME	Protein melted	16054033	Drosophila Melted modulates FOXO and TOR activity.

P08523	OMP_RAT	Olfactory marker protein	12054873	Olfactory marker protein (OMP) exhibits a beta-clam fold in solution: implications for target peptide interaction and olfactory signal transduction.

Q7TQA8	TR136_MOUSE	Taste receptor type 2 member 136	12734386	Evolutionary relationships of the Tas2r receptor gene families in mouse and human.

P47026	GWT1_YEAST	GPI-anchored wall transfer protein 1	12714589	GWT1 gene is required for inositol acylation of glycosylphosphatidylinositol anchors in yeast.

Q8ZP57	STEC_SALTY	Secreted effector kinase steC	17645553	SteC is a Salmonella kinase required for SPI-2-dependent F-actin remodelling.

P02750	A2GL_HUMAN	Leucine-rich alpha-2-glycoprotein	12223515	Molecular characterization and expression analysis of leucine-rich alpha2-glycoprotein, a novel marker of granulocytic differentiation.

O74761	PRI2_SCHPO	DNA primase large subunit	11027257	Analysis of fission yeast primase defines the checkpoint responses to aberrant S phase initiation.

P16157	ANK1_HUMAN	Ankyrin-1	9430667	An alternate promoter directs expression of a truncated, muscle- specific isoform of the human ankyrin 1 gene.

P31246	HXA2_RAT	Homeobox protein Hox-A2	1361191	Molecular cloning of a homeobox transcription factor from adult aortic smooth muscle.

P84270	DAH54_LITDA	Dahlein-5.4	11555873	Bioactive dahlein peptides from the skin secretions of the Australian aquatic frog Litoria dahlii: sequence determination by electrospray mass spectrometry.

P76535	MURQ_ECOLI	N-acetylmuramic acid 6-phosphate etherase	16452451	MurQ etherase is required by Escherichia coli in order to metabolize anhydro-N-acetylmuramic acid obtained either from the environment or from its own cell wall.

O94580	YQ77_SCHPO	Ubiquitin and WLM domain-containing protein C1442.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Z0G9	CLD3_MOUSE	Claudin-3	10562289	Manner of interaction of heterogeneous claudin species within and between tight junction strands.

Q02873	YP107_YEAST	UPF0651 protein YPL107W, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

Q25619	FAR1_ONCVO	Fatty-acid and retinol-binding protein 1	9368002	The Ov20 protein of the parasitic nematode Onchocerca volvulus. A structurally novel class of small helix-rich retinol-binding proteins.

Q9JHJ5	5HT3B_MOUSE	5-hydroxytryptamine receptor 3B	10854267	Evidence for expression of heteromeric serotonin 5-HT(3) receptors in rodents.

Q5SNZ0	GRDN_MOUSE	Girdin	19778506	DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212.

P31749	AKT1_HUMAN	RAC-alpha serine/threonine-protein kinase	16139227	Akt/PKB regulates actin organization and cell motility via Girdin/APE.

O94992	HEXI1_HUMAN	Protein HEXIM1	15713661	Compensatory contributions of HEXIM1 and HEXIM2 in maintaining the balance of active and inactive positive transcription elongation factor b complexes for control of transcription.

Q9QYK7	RNF11_MOUSE	RING finger protein 11	11042109	Identification of multiple proteins expressed in murine embryos as binding partners for the WW domains of the ubiquitin-protein ligase Nedd4.

Q9Y7P1	ERO12_SCHPO	ERO1-like protein 2	15449306	Schizosaccharomyces pombe ER oxidoreductin-like proteins SpEro1a p and SpEro1b p.

Q13231	CHIT1_HUMAN	Chitotriosidase-1	7592832	Cloning of a cDNA encoding chitotriosidase, a human chitinase produced by macrophages.

O74317	MUG98_SCHPO	Meiotically up-regulated gene 98 protein, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P35900	K1C20_HUMAN	Keratin, type I cytoskeletal 20	16608857	Keratin 20 serine 13 phosphorylation is a stress and intestinal goblet cell marker.

Q99943	PLCA_HUMAN	1-acyl-sn-glycerol-3-phosphate acyltransferase alpha	9461603	Characterization of a human lysophosphatidic acid acyltransferase that is encoded by a gene located in the class III region of the human major histocompatibility complex.

O04196	ISOA1_ARATH	Isoamylase 1, chloroplastic	15743447	Arabidopsis mutants Atisa1 and Atisa2 have identical phenotypes and lack the same multimeric isoamylase, which influences the branch point distribution of amylopectin during starch synthesis.

Q94465	GCH1_DICDI	GTP cyclohydrolase 1	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

O44516	EFN4_CAEEL	Ephrin-4	12679110	The roles of an ephrin and a semaphorin in patterning cell-cell contacts in C. elegans sensory organ development.

Q9UPC5	GPR34_HUMAN	Probable G-protein coupled receptor 34	10036181	Discovery of three novel orphan G-protein-coupled receptors.

O15530	PDPK1_HUMAN	3-phosphoinositide-dependent protein kinase 1	18616680	TUSC4/NPRL2, a novel PDK1-interacting protein, inhibits PDK1 tyrosine phosphorylation and its downstream signaling.

Q61026	NCOA2_MOUSE	Nuclear receptor coactivator 2	12477726	Tumor necrosis factor alpha receptor- and Fas-associated FLASH inhibit transcriptional activity of the glucocorticoid receptor by binding to and interfering with its interaction with p160 type nuclear receptor coactivators.

Q9UW81	NOP1_NEUCR	Opsin-1	10393943	The nop-1 gene of Neurospora crassa encodes a seven transmembrane helix retinal-binding protein homologous to archaeal rhodopsins.

Q10666	POP1_CAEEL	Protein pop-1	7585963	pop-1 encodes an HMG box protein required for the specification of a mesoderm precursor in early C. elegans embryos.

Q8L925	CRC_ARATH	Protein CRABS CLAW	15598802	Activation of CRABS CLAW in the nectaries and carpels of Arabidopsis.

Q9Y4K3	TRAF6_HUMAN	TNF receptor-associated factor 6	16286016	IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST 2 and induces T helper type 2-associated cytokines.

Q9QXM0	ABHD2_MOUSE	Abhydrolase domain-containing protein 2	15721306	Increase of smooth muscle cell migration and of intimal hyperplasia in mice lacking the alpha/beta hydrolase domain containing 2 gene.

Q9H3D4	P63_HUMAN	Tumor protein 63	9662346	A new human p53 homologue.

O94727	FRP2_SCHPO	Ferric/cupric reductase transmembrane component 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P39927	PTI1_YEAST	Protein PTI1	12819204	Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-ends.

P78875	TPP1_SCHPO	Trehalose-phosphatase	11004189	Characterization of tpp1(+) as encoding a main trehalose-6P phosphatase in the fission yeast Schizosaccharomyces pombe.

Q9NPA2	MMP25_HUMAN	Matrix metalloproteinase-25	10628838	Leukolysin/MMP25/MT6-MMP: a novel matrix metalloproteinase specifically expressed in the leukocyte lineage.

Q39032	PLCD1_ARATH	Phosphoinositide phospholipase C 1	7732004	A gene encoding a phosphatidylinositol-specific phospholipase C is induced by dehydration and salt stress in Arabidopsis thaliana.

P49019	G109B_HUMAN	G-protein coupled receptor 109B	7505609	Molecular cloning of cDNAs encoding a LD78 receptor and putative leukocyte chemotactic peptide receptors.

P04792	HSPB1_HUMAN	Heat shock protein beta-1	1560006	Copurification of small heat shock protein with alpha B crystallin from human skeletal muscle.

P16612	VEGFA_RAT	Vascular endothelial growth factor A	2320579	Amino acid and cDNA sequences of a vascular endothelial cell mitogen that is homologous to platelet-derived growth factor.

O14003	RFC3_SCHPO	Replication factor C subunit 3	16040599	Contrasting effects of Elg1-RFC and Ctf18-RFC inactivation in the absence of fully functional RFC in fission yeast.

Q12432	EAF3_YEAST	Chromatin modification-related protein EAF3	15485911	The Yaf9 component of the SWR1 and NuA4 complexes is required for proper gene expression, histone H4 acetylation, and Htz1 replacement near telomeres.

P78524	ST5_HUMAN	Suppression of tumorigenicity 5 protein	9632734	Activation of extracellular signal-regulated kinase 2 by a novel Abl- binding protein, ST5.

Q9VK45	TOR_DROME	Target of rapamycin	16219781	Drosophila target of rapamycin kinase functions as a multimer.

Q9QXN0	SHRM3_MOUSE	Protein Shroom3	10589677	Shroom, a PDZ domain-containing actin-binding protein, is required for neural tube morphogenesis in mice.

P52839	FSTL_ARATH	Flavonol sulfotransferase-like	8639757	Molecular cloning of a sulfotransferase in Arabidopsis thaliana and regulation during development and in response to infection with pathogenic bacteria.

P23470	PTPRG_HUMAN	Receptor-type tyrosine-protein phosphatase gamma	19167335	Large-scale structural analysis of the classical human protein tyrosine phosphatome.

Q9Y5H9	PCDA2_HUMAN	Protocadherin alpha-2	10380929	A striking organization of a large family of human neural cadherin- like cell adhesion genes.

P28230	CXB1_MOUSE	Gap junction beta-1 protein	19864490	Consortin, a trans-Golgi network cargo receptor for the plasma membrane targeting and recycling of connexins.

P35189	TAF14_YEAST	Transcription initiation factor TFIID subunit 14	17157260	Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs.

P24090	FETUA_RAT	Alpha-2-HS-glycoprotein	2766355	Characterization of a natural inhibitor of the insulin receptor tyrosine kinase: cDNA cloning, purification, and anti-mitogenic activity.

Q76I76	SSH2_HUMAN	Protein phosphatase Slingshot homolog 2	11832213	Control of actin reorganization by Slingshot, a family of phosphatases that dephosphorylate ADF/cofilin.

P54622	SSBP_DROME	Single-stranded DNA-binding protein, mitochondrial	11294889	Mitochondrial single-stranded DNA-binding protein is required for mitochondrial DNA replication and development in Drosophila melanogaster.

Q96J02	ITCH_HUMAN	E3 ubiquitin-protein ligase Itchy homolog	18718448	Itch regulates p45/NF-E2 in vivo by Lys63-linked ubiquitination.

P32345	PP4C_YEAST	Serine/threonine-protein phosphatase 4 catalytic subunit	14562095	Global analysis of protein localization in budding yeast.

P38287	CSH1_YEAST	Mannosyl phosphorylinositol ceramide synthase CSH1	12954640	Csg1p and newly identified Csh1p function in mannosylinositol phosphorylceramide synthesis by interacting with Csg2p.

O60682	MUSC_HUMAN	Musculin	9584154	Characterization of ABF-1, a novel basic helix-loop-helix transcription factor expressed in activated B lymphocytes.

Q9UN36	NDRG2_HUMAN	Protein NDRG2	11936845	Characterization and expression of three novel differentiation- related genes belong to the human NDRG gene family.

Q03940	RUVB1_YEAST	RuvB-like protein 1	10952318	A chromatin remodelling complex involved in transcription and DNA processing.

P38265	IML3_YEAST	Central kinetochore subunit IML3	15241623	The Iml3 protein of the budding yeast is required for the prevention of precocious sister chromatid separation in meiosis I and for sister chromatid disjunction in meiosis II.

Q05919	VPS38_YEAST	Vacuolar protein sorting-associated protein 38	9265642	Novel genes involved in endosomal traffic in yeast revealed by suppression of a targeting-defective plasma membrane ATPase mutant.

Q28298	RRBP1_CANFA	Ribosome-binding protein 1	7790375	Functional characterization of the 180 kDa ribosome receptor in vivo.

Q9HCK5	AGO4_HUMAN	Protein argonaute-4	19167051	Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs.

Q9VV96	PGSB2_DROME	Peptidoglycan-recognition protein SB2	11106397	A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster.

P40005	PFD2_YEAST	Prefoldin subunit 2	9463374	A novel protein complex promoting formation of functional alpha- and gamma-tubulin.

Q9UBL3	ASH2L_HUMAN	Set1/Ash2 histone methyltransferase complex subunit ASH2	17355966	Identification and characterization of the human Set1B histone H3- Lys4 methyltransferase complex.

P26819	ARBK2_RAT	Beta-adrenergic receptor kinase 2	1403099	The G-protein-coupled receptor kinases beta ARK1 and beta ARK2 are widely distributed at synapses in rat brain.

P50079	HSV2_YEAST	SVP1-like protein 2	15103325	Svp1p defines a family of phosphatidylinositol 3,5-bisphosphate effectors.

Q9P7F9	CTR5_SCHPO	Copper transport protein ctr5	11274192	Identification of a novel high affinity copper transport complex in the fission yeast Schizosaccharomyces pombe.

P30919	ASPG_RAT	N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase	2775174	Purification and characterization of rat liver glycosylasparaginase.

O76460	RAD54_DROME	DNA repair and recombination protein RAD54-like	9315669	The Drosophila melanogaster RAD54 homolog, DmRAD54, is involved in the repair of radiation damage and recombination.

Q9DDD7	SX19B_DANRE	Transcription factor Sox-19b	16408288	Comparative genomic and expression analysis of group B1 sox genes in zebrafish indicates their diversification during vertebrate evolution.

Q27934	PHYL_DROME	Protein phyllopod	9267026	PHYL acts to down-regulate TTK88, a transcriptional repressor of neuronal cell fates, by a SINA-dependent mechanism.

Q922X9	ANM7_MOUSE	Protein arginine N-methyltransferase 7	17048991	The testis-specific factor CTCFL cooperates with the protein methyltransferase PRMT7 in H19 imprinting control region methylation.

Q03148	SNZ1_YEAST	Pyridoxine biosynthesis protein SNZ1	12271461	Functional analysis of yeast gene families involved in metabolism of vitamins B1 and B6.

P11551	FUCP_ECOLI	L-fucose-proton symporter	2829831	Proton-linked L-fucose transport in Escherichia coli.

O23166	TR164_ARATH	Thioredoxin-like protein HCF164, chloroplastic	16997915	HCF164 receives reducing equivalents from stromal thioredoxin across the thylakoid membrane and mediates reduction of target proteins in the thylakoid lumen.

Q9SA77	ARAE1_ARATH	UDP-arabinose 4-epimerase 1	12566589	The biosynthesis of L-arabinose in plants: molecular cloning and characterization of a Golgi-localized UDP-D-xylose 4-epimerase encoded by the MUR4 gene of Arabidopsis.

P13646	K1C13_HUMAN	Keratin, type I cytoskeletal 13	7493031	Keratin 13 point mutation underlies the hereditary mucosal epithelial disorder white sponge nevus.

Q59385	COPA_ECOLI	Copper-exporting P-type ATPase A	11167016	Control of copper homeostasis in Escherichia coli by a P-type ATPase, CopA, and a MerR-like transcriptional activator, CopR.

P01743	HV102_HUMAN	Ig heavy chain V-I region HG3	6298778	Evolutionary aspects of immunoglobulin heavy chain variable region (VH) gene subgroups.

P83674	LANA_RUMGN	Ruminococcin-A	11526013	Ruminococcin A, a new lantibiotic produced by a Ruminococcus gnavus strain isolated from human feces.

P61765	STXB1_RAT	Syntaxin-binding protein 1	8247129	Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin.

Q9STR4	1A17_ARATH	1-aminocyclopropane-1-carboxylate synthase 7	20511490	Arabidopsis RING E3 ligase XBAT32 regulates lateral root production through its role in ethylene biosynthesis.

Q9JI12	VGLU2_RAT	Vesicular glutamate transporter 2	11551935	Differentiation-associated Na+-dependent inorganic phosphate cotransporter (DNPI) is a vesicular glutamate transporter in endocrine glutamatergic systems.

Q57X81	JBP2_TRYBB	Bifunctional helicase and thymine dioxygenase JBP2	19136460	JBP1 and JBP2 are two distinct thymidine hydroxylases involved in J biosynthesis in genomic DNA of African trypanosomes.

O97921	PTGDS_HORSE	Prostaglandin-H2 D-isomerase	10026099	Glutathione-independent prostaglandin D2 synthase in ram and stallion epididymal fluids: origin and regulation.

P20606	SAR1_YEAST	Small COPII coat GTPase SAR1	8419365	Purification and characterization of SAR1p, a small GTP-binding protein required for transport vesicle formation from the endoplasmic reticulum.

Q76FK4	NOL8_HUMAN	Nucleolar protein 8	15132771	Identification of NOL8, a nucleolar protein containing an RNA recognition motif (RRM), which was overexpressed in diffuse-type gastric cancer.

Q9SAZ5	AHP3_ARATH	Histidine-containing phosphotransfer protein 3	9804162	Characterization of genes for two-component phosphorelay mediators with a single HPt domain in Arabidopsis thaliana.

O43312	MTSS1_HUMAN	Metastasis suppressor protein 1	12570871	MIM-B, a putative metastasis suppressor protein, binds to actin and to protein tyrosine phosphatase delta.

P32241	VIPR1_HUMAN	Vasoactive intestinal polypeptide receptor 1	8179610	Human intestinal VIP receptor: cloning and functional expression of two cDNA encoding proteins with different N-terminal domains.

O75334	LIPA2_HUMAN	Liprin-alpha-2	9624153	Liprins, a family of LAR transmembrane protein-tyrosine phosphatase- interacting proteins.

Q54E53	CSN3_DICDI	COP9 signalosome complex subunit 3	16781008	The COP9 signalosome regulates cell proliferation of Dictyostelium discoideum.

P54784	ORC1_YEAST	Origin recognition complex subunit 1	11168584	Interactions between Mcm10p and other replication factors are required for proper initiation and elongation of chromosomal DNA replication in Saccharomyces cerevisiae.

Q53HV7	SMUG1_HUMAN	Single-strand selective monofunctional uracil DNA glycosylase	12161446	hUNG2 is the major repair enzyme for removal of uracil from U:A matches, U:G mismatches, and U in single-stranded DNA, with hSMUG1 as a broad specificity backup.

Q12256	TPO4_YEAST	Polyamine transporter 4	11171066	Multiple polyamine transport systems on the vacuolar membrane in yeast.

Q9UBV2	SE1L1_HUMAN	Protein sel-1 homolog 1	19524542	EDEM1 recognition and delivery of misfolded proteins to the SEL1L- containing ERAD complex.

Q96EP0	RNF31_HUMAN	RING finger protein 31	19136968	Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation.

P53236	RSC1_YEAST	Chromatin structure-remodeling complex subunit RSC1	12183366	Chromatin remodeling by RSC involves ATP-dependent DNA translocation.

Q9UN86	G3BP2_HUMAN	Ras GTPase-activating protein-binding protein 2	10969074	IkappaBalpha and IkappaBalpha /NF-kappa B complexes are retained in the cytoplasm through interaction with a novel partner, RasGAP SH3- binding protein 2.

P97314	CSRP2_MOUSE	Cysteine and glycine-rich protein 2	18258855	PICOT attenuates cardiac hypertrophy by disrupting calcineurin-NFAT signaling.

O35633	VIAAT_MOUSE	Vesicular inhibitory amino acid transporter	9395291	Cloning of a functional vesicular GABA and glycine transporter by screening of genome databases.

Q9LVM1	AB25B_ARATH	ABC transporter B family member 25, mitochondrial	17517886	Functional characterization of AtATM1, AtATM2, and AtATM3, a subfamily of Arabidopsis half-molecule ATP-binding cassette transporters implicated in iron homeostasis.

Q62231	SIX1_MOUSE	Homeobox protein SIX1	14628042	Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis.

P51159	RB27A_HUMAN	Ras-related protein Rab-27A	9066979	Molecular cloning and characterization of rab27a and rab27b, novel human rab proteins shared by melanocytes and platelets.

P27274	CD59_RAT	CD59 glycoprotein	1376109	Isolation and characterization of a membrane protein from rat erythrocytes which inhibits lysis by the membrane attack complex of rat complement.

Q9H6E5	TUT1_HUMAN	U6 snRNA-specific terminal uridylyltransferase 1	18172165	Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'.

O59712	YBH4_SCHPO	Uncharacterized transporter C3B8.04c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P63249	IPKA_RAT	cAMP-dependent protein kinase inhibitor alpha	1491692	The alpha- and beta-isoforms of the inhibitor protein of the 3',5'- cyclic adenosine monophosphate-dependent protein kinase: characteristics and tissue- and developmental-specific expression.

Q8R0N6	HOT_MOUSE	Hydroxyacid-oxoacid transhydrogenase, mitochondrial	17559793	Differentiation-dependent expression of Adhfe1 in adipogenesis.

Q24478	CP190_DROME	Centrosome-associated zinc finger protein CP190	15574329	The centrosomal protein CP190 is a component of the gypsy chromatin insulator.

Q70KG3	RAF1B_WHEAT	Protein RAFTIN 1B	14612572	The classical Ubisch bodies carry a sporophytically produced structural protein (RAFTIN) that is essential for pollen development.

P07737	PROF1_HUMAN	Profilin-1	7758455	Distinct biochemical characteristics of the two human profilin isoforms.

P34982	OR1D2_HUMAN	Olfactory receptor 1D2	16820410	Novel function of beta-arrestin2 in the nucleus of mature spermatozoa.

Q9GZV3	SC5A7_HUMAN	High affinity choline transporter 1	11027560	Molecular cloning of a human, hemicholinium-3-sensitive choline transporter.

Q9R1R0	LHX6_MOUSE	LIM/homeobox protein Lhx6	17376969	Lhx6 activity is required for the normal migration and specification of cortical interneuron subtypes.

O00499	BIN1_HUMAN	Myc box-dependent-interacting protein 1	10903846	Bin2, a functionally nonredundant member of the BAR adaptor gene family.

P31751	AKT2_HUMAN	RAC-beta serine/threonine-protein kinase	19713527	The E3 ligase TRAF6 regulates Akt ubiquitination and activation.

Q99N01	SO4A1_RAT	Solute carrier organic anion transporter family member 4A1	11316767	Identification of thyroid hormone transporters in humans: different molecules are involved in a tissue-specific manner.

Q9XZ63	ARMET_DROME	Mesencephalic astrocyte-derived neurotrophic factor homolog	19164766	Evidence that DmMANF is an invertebrate neurotrophic factor supporting dopaminergic neurons.

P25368	RRP7_YEAST	Ribosomal RNA-processing protein 7	14562095	Global analysis of protein localization in budding yeast.

P80511	S10AC_HUMAN	Protein S100-A12	7626002	Identification and characterization of a novel human neutrophil protein related to the S100 family.

Q9C5X8	MOCOS_ARATH	Molybdenum cofactor sulfurase	15561708	Characterization of the NifS-like domain of ABA3 from Arabidopsis thaliana provides insight into the mechanism of molybdenum cofactor sulfuration.

P39304	ULAD_ECOLI	3-keto-L-gulonate-6-phosphate decarboxylase ulaD	11741871	Utilization of L-ascorbate by Escherichia coli K-12: assignments of functions to products of the yjf-sga and yia-sgb operons.

P52286	SKP1_YEAST	Suppressor of kinetochore protein 1	8670864	The Saccharomyces cerevisiae kinetochore contains a cyclin-CDK complexing homologue, as identified by in vitro reconstitution.

Q9UQE7	SMC3_HUMAN	Structural maintenance of chromosomes protein 3	11590136	A potential role for human cohesin in mitotic spindle aster assembly.

Q54NF8	SCAR_DICDI	Protein SCAR	17314411	The N-terminus of Dictyostelium Scar interacts with Abi and HSPC300 and is essential for proper regulation and function.

O60934	NBN_HUMAN	Nibrin	9590181	The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response.

O96621	ARP2_DICDI	Actin-related protein 2	17296313	Vectors for expression of proteins with single or combinatorial fluorescent protein and tandem affinity purification tags in Dictyostelium.

Q7KHG2	JING_DROME	Zinc finger protein jing	15511644	The jing and ras1 pathways are functionally related during CNS midline and tracheal development.

Q9PSY4	FOXD1_XENLA	Forkhead box protein D1	9811586	XBF-2 is a transcriptional repressor that converts ectoderm into neural tissue.

Q05863	YL281_YEAST	Uncharacterized peptide chain release factor-like protein YLR281C, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

P23510	TNFL4_HUMAN	Tumor necrosis factor ligand superfamily member 4	7913952	Identification of a human OX-40 ligand, a costimulator of CD4+ T cells with homology to tumor necrosis factor.

Q940H6	SRK2E_ARATH	Serine/threonine-protein kinase SRK2E	12514244	ABA-activated SnRK2 protein kinase is required for dehydration stress signaling in Arabidopsis.

O70624	MYOC_MOUSE	Myocilin	12019210	Optimedin: a novel olfactomedin-related protein that interacts with myocilin.

Q9SLH0	EIL1_ARATH	ETHYLENE INSENSITIVE 3-like 1 protein	12606727	Five components of the ethylene-response pathway identified in a screen for weak ethylene-insensitive mutants in Arabidopsis.

P38628	AGM1_YEAST	Phosphoacetylglucosamine mutase	8174553	Characterization of the essential yeast gene encoding N- acetylglucosamine-phosphate mutase.

P32485	HOG1_YEAST	Mitogen-activated protein kinase HOG1	12086627	Hog1 kinase converts the Sko1-Cyc8-Tup1 repressor complex into an activator that recruits SAGA and SWI/SNF in response to osmotic stress.

Q23316	NICA_CAEEL	Nicastrin	10993067	Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing.

P30622	CLIP1_HUMAN	CAP-Gly domain-containing linker protein 1	1356075	CLIP-170 links endocytic vesicles to microtubules.

Q52S86	PODXL_CANFA	Podocalyxin	15814834	Molecular identification of canine podocalyxin-like protein 1 as a renal tubulogenic regulator.

Q56ZN6	AVP2_ARATH	Pyrophosphate-energized membrane proton pump 2	10806252	AVP2, a sequence-divergent, K(+)-insensitive H(+)-translocating inorganic pyrophosphatase from Arabidopsis.

P33402	GCYA2_HUMAN	Guanylate cyclase soluble subunit alpha-2	1683630	Molecular cloning and expression of a new alpha-subunit of soluble guanylyl cyclase. Interchangeability of the alpha-subunits of the enzyme.

Q64695	EPCR_MOUSE	Endothelial protein C receptor	8449997	cDNA-derived molecular characteristics and antibodies to a new centrosome-associated and G2/M phase-prevalent protein.

P86165	FA311_LITFA	Fallaxidin-3.1.1	18803332	The fallaxidin peptides from the skin secretion of the eastern dwarf tree frog Litoria fallax. Sequence determination by positive and negative ion electrospray mass spectrometry: antimicrobial activity and cDNA cloning of the fallaxidins.

P08069	IGF1R_HUMAN	Insulin-like growth factor 1 receptor	12138094	Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved.

O99019	LIPC_SOLDE	Light-induced protein, chloroplastic	10504562	Leaf C40.4: a carotenoid-associated protein involved in the modulation of photosynthetic efficiency?

Q9PSY4	FOXD1_XENLA	Forkhead box protein D1	10096060	Xenopus brain factor-2 controls mesoderm, forebrain and neural crest development.

P32597	STH1_YEAST	Nuclear protein STH1/NPS1	10329629	Transcriptional repression of the yeast CHA1 gene requires the chromatin-remodeling complex RSC.

Q9UIG0	BAZ1B_HUMAN	Tyrosine-protein kinase BAZ1B	15543136	The Williams syndrome transcription factor interacts with PCNA to target chromatin remodelling by ISWI to replication foci.

P05141	ADT2_HUMAN	ADP/ATP translocase 2	2168878	The human fibroblast adenine nucleotide translocator gene. Molecular cloning and sequence.

Q10280	GAF1_SCHPO	Transcription factor gaf1	9714831	Molecular cloning of gaf1, a Schizosaccharomyces pombe GATA factor, which can function as a transcriptional activator.

P42604	UXAA_ECOLI	Altronate hydrolase	3038546	The role of iron in the activation of mannonic and altronic acid hydratases, two Fe-requiring hydro-lyases.

P53277	SYF2_YEAST	Pre-mRNA-splicing factor SYF2	11105756	Functional analyses of interacting factors involved in both pre-mRNA splicing and cell cycle progression in Saccharomyces cerevisiae.

Q5SZQ8	CELF3_HUMAN	CUGBP Elav-like family member 3	11158314	The CELF family of RNA binding proteins is implicated in cell- specific and developmentally regulated alternative splicing.

Q9FL28	FLS2_ARATH	LRR receptor-like serine/threonine-protein kinase FLS2	16510871	Ligand-induced endocytosis of the pattern recognition receptor FLS2 in Arabidopsis.

P43246	MSH2_HUMAN	DNA mismatch repair protein Msh2	8942985	hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6.

P12694	ODBA_HUMAN	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial	3224821	Nucleotide and deduced amino acid sequence of the E1 alpha subunit of human liver branched-chain alpha-ketoacid dehydrogenase.

Q9DCC7	ISC2B_MOUSE	Isochorismatase domain-containing protein 2B, mitochondrial	14651853	Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.

Q12090	REXO3_YEAST	RNA exonuclease 3	14562095	Global analysis of protein localization in budding yeast.

Q9FVX0	CCA12_ARATH	Cyclin-A1-2	15557098	Progression through meiosis I and meiosis II in Arabidopsis anthers is regulated by an A-type cyclin predominately expressed in prophase I.

Q63553	SNRK_RAT	SNF-related serine/threonine-protein kinase	8654423	Molecular cloning and characterization of a novel mammalian protein kinase harboring a homology domain that defines a subfamily of serine/threonine kinases.

Q9USP4	MUG1_SCHPO	Meiotically up-regulated gene 1 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9SA41	MCA8_ARATH	Metacaspase-8	17998208	Metacaspase-8 modulates programmed cell death induced by ultraviolet light and H2O2 in Arabidopsis.

B5LUQ8	FALX6_LITFA	Preprofallaxidin-6	18803332	The fallaxidin peptides from the skin secretion of the eastern dwarf tree frog Litoria fallax. Sequence determination by positive and negative ion electrospray mass spectrometry: antimicrobial activity and cDNA cloning of the fallaxidins.

P23381	SYWC_HUMAN	Tryptophanyl-tRNA synthetase, cytoplasmic	11773625	A fragment of human TrpRS as a potent antagonist of ocular angiogenesis.

Q6NN85	SSH_DROME	Protein phosphatase Slingshot	15572110	Rho GTPases regulate axon growth through convergent and divergent signaling pathways.

P35348	ADA1A_HUMAN	Alpha-1A adrenergic receptor	7737411	Cloning, functional expression and tissue distribution of human alpha 1c-adrenoceptor splice variants.

Q13769	THOC5_HUMAN	THO complex subunit 5 homolog	19059247	Nuclear localization of the pre-mRNA associating protein THOC7 depends upon its direct interaction with Fms tyrosine kinase interacting protein (FMIP).

Q09904	NU124_SCHPO	Nucleoporin nup124	10409764	Nup124p is a nuclear pore factor of Schizosaccharomyces pombe that is important for nuclear import and activity of retrotransposon Tf1.

O13736	SLA1_SCHPO	Actin cytoskeleton-regulatory complex protein sla1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9M5K2	DLDH2_ARATH	Dihydrolipoyl dehydrogenase 2, mitochondrial	14764908	Lipoic acid-dependent oxidative catabolism of alpha-keto acids in mitochondria provides evidence for branched-chain amino acid catabolism in Arabidopsis.

Q9VF87	CYFIP_DROME	Cytoplasmic FMR1-interacting protein	14588242	Abi, Sra1, and Kette control the stability and localization of SCAR/WAVE to regulate the formation of actin-based protrusions.

Q9BVG8	KIFC3_HUMAN	Kinesin-like protein KIFC3	9782090	Cloning of a novel C-terminal kinesin (KIFC3) that maps to human chromosome 16q13-q21 and thus is a candidate gene for Bardet-Biedl syndrome.

P68871	HBB_HUMAN	Hemoglobin subunit beta	1301199	A novel beta-globin structural mutant, Hb Brescia (beta 114 Leu-Pro), causing a severe beta-thalassemia intermedia phenotype.

P61221	ABCE1_HUMAN	ATP-binding cassette sub-family E member 1	7539425	Cloning and characterization of a RNase L inhibitor. A new component of the interferon-regulated 2-5A pathway.

P20826	SCF_MOUSE	Kit ligand	1698557	The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus.

Q9PTG8	TACC3_XENLA	Transforming acidic coiled-coil-containing protein 3	10635326	Maskin is a CPEB-associated factor that transiently interacts with eIF-4E.

Q99234	DFG16_YEAST	Protein DFG16	9055077	Dissection of filamentous growth by transposon mutagenesis in Saccharomyces cerevisiae.

P35908	K22E_HUMAN	Keratin, type II cytoskeletal 2 epidermal	1380918	Characterization of human cytokeratin 2, an epidermal cytoskeletal protein synthesized late during differentiation.

P40527	ATC7_YEAST	Probable phospholipid-transporting ATPase NEO1	15314152	Molecular interactions of yeast Neo1p, an essential member of the Drs2 family of aminophospholipid translocases, and its role in membrane trafficking within the endomembrane system.

Q12380	ATG5_YEAST	Autophagy protein 5	8921905	Structural and functional analyses of APG5, a gene involved in autophagy in yeast.

Q6R0H1	LHY_ARATH	Protein LHY	16463103	The MYB transcription factor superfamily of Arabidopsis: expression analysis and phylogenetic comparison with the rice MYB family.

Q37001	1A15_ARATH	1-aminocyclopropane-1-carboxylate synthase 5	12968022	Biochemical diversity among the 1-amino-cyclopropane-1-carboxylate synthase isozymes encoded by the Arabidopsis gene family.

Q95254	GHSR_PIG	Growth hormone secretagogue receptor type 1	8688086	A receptor in pituitary and hypothalamus that functions in growth hormone release.

P38820	UBA4_YEAST	Adenylyltransferase and sulfurtransferase UBA4	18491921	The sulfurtransferase activity of Uba4 presents a link between ubiquitin-like protein conjugation and activation of sulfur carrier proteins.

Q7L590	MCM10_HUMAN	Protein MCM10 homolog	11095689	The human homolog of Saccharomyces cerevisiae Mcm10 interacts with replication factors and dissociates from nuclease-resistant nuclear structures in G(2) phase.

Q9BXP8	PAPP2_HUMAN	Pappalysin-2	11264294	Pregnancy-associated plasma protein-A2 (PAPP-A2), a novel insulin- like growth factor-binding protein-5 proteinase.

P26393	RMLA_SALTY	Glucose-1-phosphate thymidylyltransferase	8382158	Purification, characterization and HPLC assay of Salmonella glucose- 1-phosphate thymidylyltransferase from the cloned rfbA gene.

P21981	TGM2_MOUSE	Protein-glutamine gamma-glutamyltransferase 2	10334875	Organization and chromosomal mapping of mouse Gh/tissue transglutaminase gene (Tgm2).

Q92759	TF2H4_HUMAN	General transcription factor IIH subunit 4	9118947	Cloning and characterization of p52, the fifth subunit of the core of the transcription/DNA repair factor TFIIH.

Q9GN97	PGPLD_DROME	Peptidoglycan-recognition protein LD	11106397	A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster.

Q6T3U3	NPCL1_RAT	Niemann-Pick C1-like protein 1	15777641	Characterization of the putative native and recombinant rat sterol transporter Niemann-Pick C1 Like 1 (NPC1L1) protein.

P26151	FCGR1_MOUSE	High affinity immunoglobulin gamma Fc receptor I	11911823	FcgammaRI-deficient mice show multiple alterations to inflammatory and immune responses.

Q99440	CD006_HUMAN	Uncharacterized protein C4orf6	9016955	Fluorescent differential display analysis of gene expression in differentiating neuroblastoma cells.

Q12200	NPC1_YEAST	Niemann-Pick type C-related protein 1	16138904	A yeast model system for functional analysis of the Niemann-Pick type C protein 1 homolog, Ncr1p.

Q9GZQ6	NPFF1_HUMAN	Neuropeptide FF receptor 1	11024015	Identification and characterization of two G protein-coupled receptors for neuropeptide FF.

P25491	MAS5_YEAST	Mitochondrial protein import protein MAS5	1869583	Characterization of YDJ1: a yeast homologue of the bacterial dnaJ protein.

P33076	C2TA_HUMAN	MHC class II transactivator	7749984	Activation of class II MHC genes requires both the X box region and the class II transactivator (CIITA).

P27695	APEX1_HUMAN	DNA-(apurinic or apyrimidinic site) lyase	11286553	Two divalent metal ions in the active site of a new crystal form of human apurinic/apyrimidinic endonuclease, ape1: implications for the catalytic mechanism.

P54198	HIRA_HUMAN	Protein HIRA	7633437	A human homolog of the S. cerevisiae HIR1 and HIR2 transcriptional repressors cloned from the DiGeorge syndrome critical region.

P25635	PWP2_YEAST	Periodic tryptophan protein 2	8804409	PWP2, a member of the WD-repeat family of proteins, is an essential Saccharomyces cerevisiae gene involved in cell separation.

Q03558	OYE2_YEAST	NADPH dehydrogenase 2	8454584	Old Yellow Enzyme. The discovery of multiple isozymes and a family of related proteins.

Q04472	MGR3_YEAST	Mitochondrial inner membrane i-AAA protease supercomplex subunit MGR3	18843051	Mgr3p and Mgr1p are adaptors for the mitochondrial i-AAA protease complex.

P15379	CD44_MOUSE	CD44 antigen	1469058	Molecular isoforms of murine CD44 and evidence that the membrane proximal domain is not critical for hyaluronate recognition.

P51948	MAT1_HUMAN	CDK-activating kinase assembly factor MAT1	9852112	Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.

Q2ABP3	PGAP2_RAT	Post-GPI attachment to proteins factor 2	16407401	PGAP2 is essential for correct processing and stable expression of GPI-anchored proteins.

Q12465	RAX2_YEAST	Bud site selection protein RAX2	15356260	Interactions among Rax1p, Rax2p, Bud8p, and Bud9p in marking cortical sites for bipolar bud-site selection in yeast.

Q9Y234	LIPT_HUMAN	Lipoyltransferase 1, mitochondrial	10103005	Molecular cloning, structural characterization and chromosomal localization of human lipoyltransferase gene.

O43070	NBS1_SCHPO	DNA repair and telomere maintenance protein nbs1	12944481	Molecular characterization of the Schizosaccharomyces pombe nbs1+ gene involved in DNA repair and telomere maintenance.

Q8VHZ9	DDIT4_RAT	DNA damage-inducible transcript 4 protein	11884613	Identification of a novel hypoxia-inducible factor 1-responsive gene, RTP801, involved in apoptosis.

P53298	OKP1_YEAST	Central kinetochore subunit OKP1	14633972	Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes.

Q39193	SRK2I_ARATH	Serine/threonine-protein kinase SRK2I	17307925	Identification of two protein kinases required for abscisic acid regulation of seed germination, root growth, and gene expression in Arabidopsis.

P40985	HUL4_YEAST	Probable E3 ubiquitin-protein ligase HUL4	9858558	Functional domains of the rsp5 ubiquitin-protein ligase.

Q06244	PUS5_YEAST	Pseudouridylate synthase PUS5	10756195	Identification of the Saccharomyces cerevisiae RNA:pseudouridine synthase responsible for formation of psi(2819) in 21S mitochondrial ribosomal RNA.

O57437	DAZLA_XENLA	Deleted in azoospermia-like-A	10631166	A critical role for Xdazl, a germ plasm-localized RNA, in the differentiation of primordial germ cells in Xenopus.

Q01405	SC23A_MOUSE	Protein transport protein Sec23A	17452640	Physical interaction between the serotonin transporter and neuronal nitric oxide synthase underlies reciprocal modulation of their activity.

Q93091	RNAS6_HUMAN	Ribonuclease K6	8836175	Molecular cloning and characterization of a novel human ribonuclease (RNase k6): increasing diversity in the enlarging ribonuclease gene family.

Q9P6J4	YHD6_SCHPO	Uncharacterized protein C1683.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q18825	BAR1_CAEEL	Beta-catenin/armadillo-related protein 1	10952315	Distinct beta-catenins mediate adhesion and signalling functions in C. elegans.

O75689	ADAP1_HUMAN	Arf-GAP with dual PH domain-containing protein 1	12893243	Centaurin-alpha(1) associates with and is phosphorylated by isoforms of protein kinase C.

P53318	COQ6_YEAST	Ubiquinone biosynthesis monooxygenase COQ6	12721307	The Saccharomyces cerevisiae COQ6 gene encodes a mitochondrial flavin-dependent monooxygenase required for coenzyme Q biosynthesis.

Q17967	PDI1_CAEEL	Protein disulfide-isomerase 1	8760355	Baculovirus expression of two protein disulphide isomerase isoforms from Caenorhabditis elegans and characterization of prolyl 4- hydroxylases containing one of these polypeptides as their beta subunit.

P53301	CRH1_YEAST	Probable glycosidase CRH1	10757808	A novel family of cell wall-related proteins regulated differently during the yeast life cycle.

Q9D0P7	PSRC1_MOUSE	Proline/serine-rich coiled-coil protein 1	17310996	p53 downstream target DDA3 is a novel microtubule-associated protein that interacts with end-binding protein EB3 and activates beta-catenin pathway.

Q9Y2T6	GPR55_HUMAN	G-protein coupled receptor 55	18757503	The GPR55 ligand L-alpha-lysophosphatidylinositol promotes RhoA- dependent Ca2+ signaling and NFAT activation.

P0C074	YSF3_YEAST	RDS3 complex subunit 10	15565172	Proteomic analysis identifies a new complex required for nuclear pre- mRNA retention and splicing.

P46669	RPA43_YEAST	DNA-directed RNA polymerase I subunit RPA43	7592632	Gene RPA43 in Saccharomyces cerevisiae encodes an essential subunit of RNA polymerase I.

P35169	TOR1_YEAST	Serine/threonine-protein kinase TOR1	10198052	Regulation of ribosome biogenesis by the rapamycin-sensitive TOR- signaling pathway in Saccharomyces cerevisiae.

Q09098	PATE4_MOUSE	Prostate and testis expressed protein 4	18387948	PATE gene clusters code for multiple, secreted TFP/Ly-6/uPAR proteins that are expressed in reproductive and neuron-rich tissues and possess neuromodulatory activity.

Q64535	ATP7B_RAT	Copper-transporting ATPase 2	7951327	The LEC rat has a deletion in the copper transporting ATPase gene homologous to the Wilson disease gene.

P58308	OX2R_MOUSE	Orexin receptor type 2	15256537	Genomic organization of mouse orexin receptors: characterization of two novel tissue-specific splice variants.

O13994	YEGD_SCHPO	UPF0596 Golgi apparatus membrane protein C26H5.13c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P87240	NOT2_SCHPO	General negative regulator of transcription subunit 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

B5LUQ4	FALX1_LITFA	Preprofallaxidin-1	18803332	The fallaxidin peptides from the skin secretion of the eastern dwarf tree frog Litoria fallax. Sequence determination by positive and negative ion electrospray mass spectrometry: antimicrobial activity and cDNA cloning of the fallaxidins.

Q04003	SAS4_YEAST	Something about silencing protein 4	11731480	The silencing complex SAS-I links histone acetylation to the assembly of repressed chromatin by CAF-I and Asf1 in Saccharomyces cerevisiae.

Q9UII4	HERC5_HUMAN	E3 ISG15--protein ligase HERC5	10581175	A novel human gene encoding HECT domain and RCC1-like repeats interacts with cyclins and is potentially regulated by the tumor suppressor proteins.

P21399	ACOC_HUMAN	Cytoplasmic aconitate hydratase	19762597	An E3 ligase possessing an iron responsive hemerythrin domain is a regulator of iron homeostasis.

P32320	CDD_HUMAN	Cytidine deaminase	15689149	Structure of human cytidine deaminase bound to a potent inhibitor.

P23644	TOM40_YEAST	Mitochondrial import receptor subunit TOM40	9774667	Preprotein translocase of the outer mitochondrial membrane: molecular dissection and assembly of the general import pore complex.

O81081	LAC2_ARATH	Laccase-2	16804053	Mutant identification and characterization of the laccase gene family in Arabidopsis.

Q03289	PFA5_YEAST	Palmitoyltransferase PFA5	16186255	The vacuolar DHHC-CRD protein Pfa3p is a protein acyltransferase for Vac8p.

P97480	EYA3_MOUSE	Eyes absent homolog 3	10490620	Cooperation of six and eya in activation of their target genes through nuclear translocation of Eya.

P40336	VP26A_MOUSE	Vacuolar protein sorting-associated protein 26A	15078902	Cargo-selective endosomal sorting for retrieval to the Golgi requires retromer.

P25621	FEN2_YEAST	Pantothenate transporter FEN2	10373490	The fenpropimorph resistance gene FEN2 from Saccharomyces cerevisiae encodes a plasma membrane H+-pantothenate symporter.

P64943	PAFA_MYCTU	Pup--protein ligase	19448618	Bacterial ubiquitin-like modifier Pup is deamidated and conjugated to substrates by distinct but homologous enzymes.

Q9NVV9	THAP1_HUMAN	THAP domain-containing protein 1	18073205	Structure-function analysis of the THAP zinc finger of THAP1, a large C2CH DNA-binding module linked to Rb/E2F pathways.

Q924N5	ACBG1_RAT	Long-chain-fatty-acid--CoA ligase ACSBG1	16469493	Tissue-cell- and species-specific expression of gonadotropin- regulated long chain acyl-CoA synthetase (GR-LACS) in gonads, adrenal and brain. Identification of novel forms in the brain.

P32334	MSB2_YEAST	Protein MSB2	1514328	A Ser/Thr-rich multicopy suppressor of a cdc24 bud emergence defect.

P32586	PYP2_SCHPO	Tyrosine-protein phosphatase 2	7657164	Pyp1 and Pyp2 PTPases dephosphorylate an osmosensing MAP kinase controlling cell size at division in fission yeast.

P60568	IL2_HUMAN	Interleukin-2	6608729	T-cell growth factor: complete nucleotide sequence and organization of the gene in normal and malignant cells.

Q9LI83	ALA10_ARATH	Phospholipid-transporting ATPase 10	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

A2VCW5	S38A5_RAT	Sodium-coupled neutral amino acid transporter 5	11698233	Cloning and functional characterization of a new subtype of the amino acid transport system N.

Q9USH8	GLU2B_SCHPO	Glucosidase 2 subunit beta	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P51813	BMX_HUMAN	Cytoplasmic tyrosine-protein kinase BMX	9520419	Etk/Bmx, a tyrosine kinase with a pleckstrin-homology domain, is an effector of phosphatidylinositol 3'-kinase and is involved in interleukin 6-induced neuroendocrine differentiation of prostate cancer cells.

Q03103	ERO1_YEAST	Endoplasmic oxidoreductin-1	10982384	Two pairs of conserved cysteines are required for the oxidative activity of Ero1p in protein disulfide bond formation in the endoplasmic reticulum.

Q36724	COX1_BLAGE	Cytochrome c oxidase subunit 1	8044176	Cytochrome c oxidase subunit I from the cockroach Blattella germanica: cloning, developmental pattern and tissue expression.

Q9XZE5	PP2AA_DICDI	Serine/threonine-protein phosphatase 2A catalytic subunit A	10491107	Biochemical characterization of a Dictyostelium myosin II heavy-chain phosphatase that promotes filament assembly.

Q24573	DRI_DROME	Protein dead ringer	12620977	The dead ringer/retained transcriptional regulatory gene is required for positioning of the longitudinal glia in the Drosophila embryonic CNS.

Q01167	FOXK2_HUMAN	Forkhead box protein K2	12402362	Solution structure of the DNA-binding domain of interleukin enhancer binding factor 1 (FOXK1a).

Q9UTR8	YLP3_SCHPO	Uncharacterized protein C1006.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q24306	IAP1_DROME	Apoptosis 1 inhibitor	17397804	Evolution of mitochondrial cell death pathway: Proapoptotic role of HtrA2/Omi in Drosophila.

Q9HB65	ELL3_HUMAN	RNA polymerase II elongation factor ELL3	10882741	Identification, cloning, expression, and biochemical characterization of the testis-specific RNA polymerase II elongation factor ELL3.

Q06488	RSC2_YEAST	Chromatin structure-remodeling complex subunit RSC2	10619019	Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains.

P38902	RPB11_YEAST	DNA-directed RNA polymerase II subunit RPB11	16537912	cis- and trans-Acting determinants of transcription termination by yeast RNA polymerase II.

P60953	CDC42_HUMAN	Cell division control protein 42 homolog	12612085	The TRE17 oncogene encodes a component of a novel effector pathway for Rho GTPases Cdc42 and Rac1 and stimulates actin remodeling.

Q9UBF2	COPG2_HUMAN	Coatomer subunit gamma-2	11056392	Identification and characterization of novel isoforms of COP I subunits.

P32495	NHP2_YEAST	H/ACA ribonucleoprotein complex subunit 2	9848653	Cbf5p, a potential pseudouridine synthase, and Nhp2p, a putative RNA- binding protein, are present together with Gar1p in all H BOX/ACA- motif snoRNPs and constitute a common bipartite structure.

Q15414	RBY1A_HUMAN	RNA-binding motif protein, Y chromosome, family 1 member A1/C	9598316	Structure and organization of the RBMY genes on the human Y chromosome: transposition and amplification of an ancestral autosomal hnRNPG gene.

P37646	YHJH_ECOLI	Cyclic di-GMP phosphodiesterase YhjH	18765794	Inverse regulatory coordination of motility and curli-mediated adhesion in Escherichia coli.

Q08550	MPC54_YEAST	Meiotic plaque component protein 54	12796288	Ady4p and Spo74p are components of the meiotic spindle pole body that promote growth of the prospore membrane in Saccharomyces cerevisiae.

P41412	RES2_SCHPO	Cell division cycle-related protein res2/pct1	8168485	res2+, a new member of the cdc10+/SWI4 family, controls the 'start' of mitotic and meiotic cycles in fission yeast.

Q9Y4A5	TRRAP_HUMAN	Transformation/transcription domain-associated protein	9708738	The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins.

P15954	COX7C_HUMAN	Cytochrome c oxidase subunit 7C, mitochondrial	2155413	Sequence of a cDNA specifying subunit VIIc of human cytochrome c oxidase.

O04928	CDS1_ARATH	Phosphatidate cytidylyltransferase	9085581	Complementary DNAs encoding eukaryotic-type cytidine-5'-diphosphate- diacylglycerol synthases of two plant species.

Q9P6P7	YKCG_SCHPO	Uncharacterized RNA-binding protein C644.16	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8INM3	SLE_DROME	Protein slender lobes	15848394	The slender lobes gene, identified by retarded mushroom body development, is required for proper nucleolar organization in Drosophila.

Q8BXG3	IFT57_MOUSE	Intraflagellar transport protein 57 homolog	17931679	Spatial distribution of intraflagellar transport proteins in vertebrate photoreceptors.

Q22866	TPM1_CAEEL	Tropomyosin isoforms a/b/d/f	16399684	Integration of male mating and feeding behaviors in Caenorhabditis elegans.

Q6IRB2	HES1A_XENLA	Transcription factor HES-1-A	10976052	Hes6 acts in a positive feedback loop with the neurogenins to promote neuronal differentiation.

Q9STX1	ACBP3_ARATH	Acyl-CoA-binding domain-containing protein 3	16231156	Arabidopsis ACBP3 is an extracellularly targeted acyl-CoA-binding protein.

P50542	PEX5_HUMAN	Peroxisomal targeting signal 1 receptor	19197237	Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19.

Q9EQY0	ERN1_MOUSE	Serine/threonine-protein kinase/endoribonuclease IRE1	11850408	IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response.

Q9NS26	SPNXA_HUMAN	Sperm protein associated with the nucleus on the X chromosome A	10906052	Spermatid-specific expression of the novel X-linked gene product SPAN-X localized to the nucleus of human spermatozoa.

O93464	CCKN_CARAU	Cholecystokinin	8092330	CCK/gastrin-like immunoreactivity in brain and gut, and CCK suppression of feeding in goldfish.

Q9NZQ8	TRPM5_HUMAN	Transient receptor potential cation channel subfamily M member 5	10607831	Identification and characterization of MTR1, a novel gene with homology to melastatin (MLSN1) and the trp gene family located in the BWS-WT2 critical region on chromosome 11p15.5 and showing allele- specific expression.

P14920	OXDA_HUMAN	D-amino-acid oxidase	2901986	Molecular cloning and sequence analysis of cDNA encoding human kidney D-amino acid oxidase.

P38484	INGR2_HUMAN	Interferon gamma receptor 2	8124716	Identification and sequence of an accessory factor required for activation of the human interferon gamma receptor.

Q9UR24	RHP26_SCHPO	DNA repair protein rhp26	10480889	Transcription dependence and the roles of two excision repair pathways for UV damage in fission yeast Schizosaccharomyces pombe.

Q9EQT3	RHOU_MOUSE	Rho-related GTP-binding protein RhoU	11459829	Wrch-1, a novel member of the Rho gene family that is regulated by Wnt-1.

Q16836	HCDH_HUMAN	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	8687463	Human short-chain L-3-hydroxyacyl-CoA dehydrogenase: cloning and characterization of the coding sequence.

P08670	VIME_HUMAN	Vimentin	11889032	Conserved segments 1A and 2B of the intermediate filament dimer: their atomic structures and role in filament assembly.

Q9QZR9	CO4A4_MOUSE	Collagen alpha-4(IV) chain	10534397	Insertional mutation of the collagen genes Col4a3 and Col4a4 in a mouse model of Alport syndrome.

Q6P1X5	TAF2_HUMAN	Transcription initiation factor TFIID subunit 2	9418870	CIF150, a human cofactor for transcription factor IID-dependent initiator function.

Q19626	VATB_CAEEL	Probable V-type proton ATPase subunit B	15866168	Repression of cell-cell fusion by components of the C. elegans vacuolar ATPase complex.

P0AEC8	DCUS_ECOLI	Sensor protein dcuS	9973351	Identification and characterization of a two-component sensor-kinase and response-regulator system (DcuS-DcuR) controlling gene expression in response to C4-dicarboxylates in Escherichia coli.

Q15628	TRADD_HUMAN	Tumor necrosis factor receptor type 1-associated DEATH domain protein	10892748	A novel mechanism of TRAF signaling revealed by structural and functional analyses of the TRADD-TRAF2 interaction.

Q9NUB1	ACS2L_HUMAN	Acetyl-coenzyme A synthetase 2-like, mitochondrial	16788062	Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2.

Q61026	NCOA2_MOUSE	Nuclear receptor coactivator 2	8643509	GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptors.

O60749	SNX2_HUMAN	Sorting nexin-2	9819414	Identification of a family of sorting nexin molecules and characterization of their association with receptors.

P53958	BOP3_YEAST	Protein BOP3	15796894	Overexpression of Bop3 confers resistance to methylmercury in Saccharomyces cerevisiae through interaction with other proteins such as Fkh1, Rts1, and Msn2.

Q8K0L2	ENTP8_MOUSE	Ectonucleoside triphosphate diphosphohydrolase 8	15122917	Cloning and characterization of mouse nucleoside triphosphate diphosphohydrolase-8.

Q8IRG6	SPT16_DROME	FACT complex subunit spt16	12815073	Drosophila FACT contributes to Hox gene expression through physical and functional interactions with GAGA factor.

P38790	HTD2_YEAST	Hydroxyacyl-thioester dehydratase type 2, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

Q9Y572	RIPK3_HUMAN	Receptor-interacting serine/threonine-protein kinase 3	10339433	Identification of RIP3, a RIP-like kinase that activates apoptosis and NFkappaB.

P63073	IF4E_MOUSE	Eukaryotic translation initiation factor 4E	18805096	The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP.

Q9Z0K8	VNN1_MOUSE	Pantetheinase	8934567	Vanin-1, a novel GPI-linked perivascular molecule involved in thymus homing.

Q9Y696	CLIC4_HUMAN	Chloride intracellular channel protein 4	12163479	AKAP350 at the Golgi apparatus. II. Association of AKAP350 with a novel chloride intracellular channel (CLIC) family member.

Q8TEY7	UBP33_HUMAN	Ubiquitin carboxyl-terminal hydrolase 33	19424180	The deubiquitinases USP33 and USP20 coordinate beta2 adrenergic receptor recycling and resensitization.

Q9UQ53	MGT4B_HUMAN	Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B	10372966	A novel second isoenzyme of the human UDP-N- acetylglucosamine:alpha1,3-D-mannoside beta1,4-N- acetylglucosaminyltransferase family: cDNA cloning, expression, and chromosomal assignment.

Q9UHL4	DPP2_HUMAN	Dipeptidyl peptidase 2	10567372	Sequence, purification, and cloning of an intracellular serine protease, quiescent cell proline dipeptidase.

P51142	DVL2_XENLA	Segment polarity protein dishevelled homolog DVL-2	12421719	Neural tube closure requires Dishevelled-dependent convergent extension of the midline.

P84915	VP13A_POLPI	Venom protein 13a	15150833	Mass spectrometric characterization of two novel inflammatory peptides from the venom of the social wasp Polybia paulista.

Q9LFH3	LOG4_ARATH	Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG4	19837870	Functional analyses of LONELY GUY cytokinin-activating enzymes reveal the importance of the direct activation pathway in Arabidopsis.

Q96KS0	EGLN2_HUMAN	Egl nine homolog 2	12039559	The use of dioxygen by HIF prolyl hydroxylase (PHD1).

Q9UBP0	SPAST_HUMAN	Spastin	16219033	Human spastin has multiple microtubule-related functions.

P27111	CYNR_ECOLI	HTH-type transcriptional regulator cynR	1592818	The Escherichia coli K-12 cyn operon is positively regulated by a member of the lysR family.

Q02875	YP105_YEAST	Uncharacterized protein YPL105C	14562095	Global analysis of protein localization in budding yeast.

O04532	FH8_ARATH	Formin-like protein 8	16313636	Arabidopsis group Ie formins localize to specific cell membrane domains, interact with actin-binding proteins and cause defects in cell expansion upon aberrant expression.

Q5B037	AXE1_EMENI	Acetylxylan esterase A	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

Q9NQ25	SLAF7_HUMAN	SLAM family member 7	11698418	Activation of NK cell-mediated cytotoxicity by a SAP-independent receptor of the CD2 family.

P40692	MLH1_HUMAN	DNA mismatch repair protein Mlh1	8128251	Mutation of a mutL homolog in hereditary colon cancer.

Q05655	KPCD_HUMAN	Protein kinase C delta type	12628935	Protein kinase Cdelta is responsible for constitutive and DNA damage- induced phosphorylation of Rad9.

P35582	FOXA1_MOUSE	Hepatocyte nuclear factor 3-alpha	10049364	Inactivation of the winged helix transcription factor HNF3alpha affects glucose homeostasis and islet glucagon gene expression in vivo.

Q6PGK7	CHSTA_MOUSE	Carbohydrate sulfotransferase 10	12213450	Mice deficient for the HNK-1 sulfotransferase show alterations in synaptic efficacy and spatial learning and memory.

Q8C310	ROBO4_MOUSE	Roundabout homolog 4	12941633	Robo4 is a vascular-specific receptor that inhibits endothelial migration.

P32578	SIP1_YEAST	SNF1 protein kinase subunit beta-1	9121458	The Snf1 protein kinase and its activating subunit, Snf4, interact with distinct domains of the Sip1/Sip2/Gal83 component in the kinase complex.

P33893	GATB_YEAST	Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

O00910	STATA_DICDI	Signal transducer and activator of transcription A	9200609	SH2 signaling in a lower eukaryote: a STAT protein that regulates stalk cell differentiation in dictyostelium.

P49893	WN11B_XENLA	Protein Wnt-11b	17663724	Wnt11 stimulation induces polarized accumulation of Dishevelled at apical adherens junctions through Frizzled7.

Q9VUT6	GALT8_DROME	Polypeptide N-acetylgalactosaminyltransferase 8	12829714	Functional characterization and expression analysis of members of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family from Drosophila melanogaster.

P53157	FMP37_YEAST	UPF0041 protein FMP37	14562095	Global analysis of protein localization in budding yeast.

P81277	PRRP_HUMAN	Prolactin-releasing peptide	9607765	A prolactin-releasing peptide in the brain.

P25582	SPB1_YEAST	AdoMet-dependent rRNA methyltransferase SPB1	10648622	Spb1p is a yeast nucleolar protein associated with Nop1p and Nop58p that is able to bind S-adenosyl-L-methionine in vitro.

Q92637	FCGRB_HUMAN	High affinity immunoglobulin gamma Fc receptor IB	1430234	Novel Fc gamma receptor I family gene products in human mononuclear cells.

Q8RYC8	ARFS_ARATH	Auxin response factor 19	15659631	Functional genomic analysis of the AUXIN RESPONSE FACTOR gene family members in Arabidopsis thaliana: unique and overlapping functions of ARF7 and ARF19.

P0AF98	LPTF_ECOLI	Lipopolysaccharide export system permease protein lptF	15919996	Global topology analysis of the Escherichia coli inner membrane proteome.

Q9VGX3	FAU_DROME	Protein anoxia up-regulated	9878744	Gene regulation by O2 deprivation: an anoxia-regulated novel gene in Drosophila melanogaster.

Q8BVN9	MAEL_MOUSE	Protein maelstrom homolog	20011505	Cytoplasmic compartmentalization of the fetal piRNA pathway in mice.

O75843	AP1G2_HUMAN	AP-1 complex subunit gamma-like 2	9762922	Cloning, expression, and localization of a novel gamma-adaptin-like molecule.

Q8WYA1	BMAL2_HUMAN	Aryl hydrocarbon receptor nuclear translocator-like protein 2	10864977	The basic helix-loop-helix-PAS protein MOP9 is a brain-specific heterodimeric partner of circadian and hypoxia factors.

Q9SGW3	RP12A_ARATH	26S proteasome non-ATPase regulatory subunit RPN12A	11826296	Cytokinin growth responses in Arabidopsis involve the 26S proteasome subunit RPN12.

P54789	ORC1_SCHPO	Origin recognition complex subunit 1	11850415	Purification and characterization of the Schizosaccharomyces pombe origin recognition complex: interaction with origin DNA and Cdc18 protein.

Q08910	YO387_YEAST	VEL1-related protein YOR387C	11935221	Sequence-based approach for identification of cell wall proteins in Saccharomyces cerevisiae.

P0A761	NANE_ECOLI	Putative N-acetylmannosamine-6-phosphate 2-epimerase	9864311	Convergent pathways for utilization of the amino sugars N- acetylglucosamine, N-acetylmannosamine, and N-acetylneuraminic acid by Escherichia coli.

Q9P6P9	PDK_SCHPO	[Pyruvate dehydrogenase [lipoamide]] kinase, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P27937	AMY3B_ORYSJ	Alpha-amylase isozyme 3B	1714318	Characterization of an alpha-amylase multigene cluster in rice.

P22147	XRN1_YEAST	5'-3' exoribonuclease 1	12423748	KEM1 is involved in filamentous growth of Saccharomyces cerevisiae.

O74957	AGO1_SCHPO	Protein argonaute	14704433	RNAi-mediated targeting of heterochromatin by the RITS complex.

P98177	FOXO4_HUMAN	Forkhead box protein O4	15126506	FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1).

P38418	LOX2_ARATH	Lipoxygenase 2, chloroplastic	18949503	Diversity of the enzymatic activity in the lipoxygenase gene family of Arabidopsis thaliana.

Q06032	CST9_YEAST	Chromosome stability protein 9	10943844	Zip3 provides a link between recombination enzymes and synaptonemal complex proteins.

Q8WUP2	FBLI1_HUMAN	Filamin-binding LIM protein 1	12679033	Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation.

Q08211	DHX9_HUMAN	ATP-dependent RNA helicase A	15084609	Arginine methylation of RNA helicase a determines its subcellular localization.

P15651	ACADS_RAT	Short-chain specific acyl-CoA dehydrogenase, mitochondrial	2777793	Molecular cloning and nucleotide sequence of cDNAs encoding the precursors of rat long chain acyl-coenzyme A, short chain acyl- coenzyme A, and isovaleryl-coenzyme A dehydrogenases. Sequence homology of four enzymes of the acyl-CoA dehydrogenase family.

P12007	IVD_RAT	Isovaleryl-CoA dehydrogenase, mitochondrial	2777793	Molecular cloning and nucleotide sequence of cDNAs encoding the precursors of rat long chain acyl-coenzyme A, short chain acyl- coenzyme A, and isovaleryl-coenzyme A dehydrogenases. Sequence homology of four enzymes of the acyl-CoA dehydrogenase family.

Q9UPY3	DICER_HUMAN	Endoribonuclease Dicer	14749716	Characterization of the interactions between mammalian PAZ PIWI domain proteins and Dicer.

Q7G191	ALDO4_ARATH	Aldehyde oxidase 4	10972874	Abscisic aldehyde oxidase in leaves of Arabidopsis thaliana.

Q9Y6A1	POMT1_HUMAN	Protein O-mannosyl-transferase 1	14699049	Demonstration of mammalian protein O-mannosyltransferase activity: coexpression of POMT1 and POMT2 required for enzymatic activity.

Q06145	GIP_RAT	Gastric inhibitory polypeptide	8446620	Glucose-dependent insulinotropic peptide: structure of the precursor and tissue-specific expression in rat.

P32389	MET4_YEAST	Transcriptional activator of sulfur metabolism MET4	15689486	The yeast ubiquitin ligase SCFMet30 regulates heavy metal response.

Q6WV17	GALT5_DROME	Polypeptide N-acetylgalactosaminyltransferase 5	12829714	Functional characterization and expression analysis of members of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family from Drosophila melanogaster.

Q9HAN9	NMNA1_HUMAN	Nicotinamide mononucleotide adenylyltransferase 1	11027696	Molecular cloning, chromosomal localization, tissue mRNA levels, bacterial expression, and enzymatic properties of human NMN adenylyltransferase.

O73622	PAT_XENLA	Protein Pat	9622619	Xpat, a gene expressed specifically in germ plasm and primordial germ cells of Xenopus laevis.

Q16548	B2LA1_HUMAN	Bcl-2-related protein A1	8605321	Cloning of human Bcl-2 homologue: inflammatory cytokines induce human A1 in cultured endothelial cells.

Q9UI12	VATH_HUMAN	V-type proton ATPase subunit H	9620685	Interactions between HIV1 Nef and vacuolar ATPase facilitate the internalization of CD4.

A1Z9E2	LIN54_DROME	Protein lin-54 homolog	12490953	Role for a Drosophila Myb-containing protein complex in site-specific DNA replication.

P84801	GRFIN_GRISQ	Griffithsin	15613479	Isolation and characterization of griffithsin, a novel HIV- inactivating protein, from the red alga Griffithsia sp.

P35604	COPZ1_BOVIN	Coatomer subunit zeta-1	8276893	Zeta-COP, a subunit of coatomer, is required for COP-coated vesicle assembly.

P00522	ABL_DROME	Tyrosine-protein kinase Abl	2832740	DNA sequence, structure, and tyrosine kinase activity of the Drosophila melanogaster Abelson proto-oncogene homolog.

Q9FK12	CRF3_ARATH	Ethylene-responsive transcription factor CRF3	16832061	A subset of Arabidopsis AP2 transcription factors mediates cytokinin responses in concert with a two-component pathway.

Q8WXF3	REL3_HUMAN	Relaxin-3	14522968	Identification of relaxin-3/INSL7 as an endogenous ligand for the orphan G-protein coupled receptor GPCR135.

P32121	ARRB2_HUMAN	Beta-arrestin-2	19363159	Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2.

Q12196	RIO1_YEAST	Serine/threonine-protein kinase RIO1	11972772	Yeast Rio1p is the founding member of a novel subfamily of protein serine kinases involved in the control of cell cycle progression.

O13699	MU132_SCHPO	Meiotically up-regulated gene 132 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12050	ELG1_YEAST	Telomere length regulation protein ELG1	12912927	Elg1 forms an alternative RFC complex important for DNA replication and genome integrity.

Q924N5	ACBG1_RAT	Long-chain-fatty-acid--CoA ligase ACSBG1	11381125	Cloning and characterization of a hormonally regulated rat long chain acyl-CoA synthetase.

P02786	TFR1_HUMAN	Transferrin receptor protein 1	6090955	Primary structure of human transferrin receptor deduced from the mRNA sequence.

P38255	RXT2_YEAST	Transcriptional regulatory protein RXT2	16275642	Raf60, a novel component of the Rpd3 histone deacetylase complex required for Rpd3 activity in Saccharomyces cerevisiae.

O95168	NDUB4_HUMAN	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

P53599	SSK2_YEAST	MAP kinase kinase kinase SSK2	7624781	Activation of yeast PBS2 MAPKK by MAPKKKs or by binding of an SH3- containing osmosensor.

Q99PG4	RGS18_MOUSE	Regulator of G-protein signaling 18	11342430	A novel regulator of G-protein signaling bearing GAP activity for Galphai and Galphaq in megakaryocytes.

P53061	ZIP2_YEAST	Protein ZIP2	15805472	Multiple branches of the meiotic recombination pathway contribute independently to homolog pairing and stable juxtaposition during meiosis in budding yeast.

P36130	CAF4_YEAST	CCR4-associated factor 4	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q6YAT4	SGCE_RAT	Epsilon-sarcoglycan	14625080	Cloning, developmental regulation and neural localization of rat epsilon-sarcoglycan.

Q9SZF7	SHR_ARATH	Protein SHORT-ROOT	16640459	Whole-genome analysis of the SHORT-ROOT developmental pathway in Arabidopsis.

Q54HS3	SET1_DICDI	Histone-lysine N-methyltransferase set1	16469305	Developmental timing in Dictyostelium is regulated by the Set1 histone methyltransferase.

O54781	SRPK2_MOUSE	Serine/threonine-protein kinase SRPK2	9446799	Novel SR-protein-specific kinase, SRPK2, disassembles nuclear speckles.

Q9YHT4	HEM0_DANRE	5-aminolevulinate synthase, erythroid-specific, mitochondrial	9806542	Positional cloning of the zebrafish sauternes gene: a model for congenital sideroblastic anaemia.

Q9NAN1	SAE2_CAEEL	SUMO-activating enzyme subunit uba-2	15990876	Chromatin regulation and sumoylation in the inhibition of Ras-induced vulval development in Caenorhabditis elegans.

Q8JGS1	STIL_DANRE	SCL-interrupting locus protein homolog	12006978	Insertional mutagenesis in zebrafish rapidly identifies genes essential for early vertebrate development.

Q84WV9	QPCT_ARATH	Glutaminyl-peptide cyclotransferase	17261077	Isolation and characterization of the glutaminyl cyclases from Solanum tuberosum and Arabidopsis thaliana: implications for physiological functions.

Q92838	EDA_HUMAN	Ectodysplasin-A	8696334	X-linked anhidrotic (hypohidrotic) ectodermal dysplasia is caused by mutation in a novel transmembrane protein.

Q54D73	FHBB_DICDI	Flavohemoprotein B	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q8I8W7	FEM3_CAERE	Sex-determination protein fem-3	12477393	Rapid coevolution of the nematode sex-determining genes fem-3 and tra-2.

O54990	PROM1_MOUSE	Prominin-1	9356465	Prominin, a novel microvilli-specific polytopic membrane protein of the apical surface of epithelial cells, is targeted to plasmalemmal protrusions of non-epithelial cells.

Q58EE9	GFAP_DANRE	Glial fibrillary acidic protein	12801639	Structural and functional characterization of the zebrafish gene for glial fibrillary acidic protein, GFAP.

Q9NS56	TOPRS_HUMAN	E3 ubiquitin-protein ligase Topors	17803295	TOPORS functions as a SUMO-1 E3 ligase for chromatin-modifying proteins.

P18537	FRIZ_DROME	Frizzled	2493583	A Drosophila tissue polarity locus encodes a protein containing seven potential transmembrane domains.

O75381	PEX14_HUMAN	Peroxisomal membrane protein PEX14	10704444	PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis.

O00746	NDKM_HUMAN	Nucleoside diphosphate kinase, mitochondrial	9099850	nm23-H4, a new member of the family of human nm23/nucleoside diphosphate kinase genes localised on chromosome 16p13.

O95169	NDUB8_HUMAN	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

O15230	LAMA5_HUMAN	Laminin subunit alpha-5	11821406	Recombinant human laminin-10 (alpha5beta1gamma1). Production, purification, and migration-promoting activity on vascular endothelial cells.

P15121	ALDR_HUMAN	Aldose reductase	2112546	Cloning and expression of human aldose reductase.

Q15910	EZH2_HUMAN	Histone-lysine N-methyltransferase EZH2	8954776	Cloning of a human homolog of the Drosophila enhancer of zeste gene (EZH2) that maps to chromosome 21q22.2.

Q9LUW0	LOX5_ARATH	Lipoxygenase 5, chloroplastic	18949503	Diversity of the enzymatic activity in the lipoxygenase gene family of Arabidopsis thaliana.

Q93086	P2RX5_HUMAN	P2X purinoceptor 5	9414125	Primary structure and expression of a naturally truncated human P2X ATP receptor subunit from brain and immune system.

Q9WVI9	JIP1_MOUSE	C-Jun-amino-terminal kinase-interacting protein 1	10712642	Spatial, temporal and subcellular localization of islet-brain 1 (IB1), a homologue of JIP-1, in mouse brain.

Q9LD55	EIF3A_ARATH	Eukaryotic translation initiation factor 3 subunit A	11042177	Plant initiation factor 3 subunit composition resembles mammalian initiation factor 3 and has a novel subunit.

Q9NPF5	DMAP1_HUMAN	DNA methyltransferase 1-associated protein 1	10888872	DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci.

Q12267	SMC4_YEAST	Structural maintenance of chromosomes protein 4	10811823	The condensin complex governs chromosome condensation and mitotic transmission of rDNA.

Q01097	NMDE2_MOUSE	Glutamate [NMDA] receptor subunit epsilon-2	19243221	Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning.

Q9P086	MED11_HUMAN	Mediator of RNA polymerase II transcription subunit 11	12584197	Identification of mammalian Mediator subunits with similarities to yeast Mediator subunits Srb5, Srb6, Med11, and Rox3.

Q06671	ATG23_YEAST	Autophagy-related protein 23	14504273	Atg23 is essential for the cytoplasm to vacuole targeting pathway and efficient autophagy but not pexophagy.

Q8WN98	MIOX_PIG	Inositol oxygenase	11716759	Myo-inositol oxygenase: molecular cloning and expression of a unique enzyme that oxidizes myo-inositol and d-chiro-inositol.

O55162	LYPD3_RAT	Ly6/PLAUR domain-containing protein 3	9788443	Cloning and functional characterization of a new phosphatidyl- inositol anchored molecule of a metastasizing rat pancreatic tumor.

Q01740	FMO1_HUMAN	Dimethylaniline monooxygenase [N-oxide-forming] 1	1712018	Cloning, primary sequence, and chromosomal mapping of a human flavin- containing monooxygenase (FMO1).

Q9M1W4	HMT2_ARATH	Homocysteine S-methyltransferase 2	10747987	Characterization and functional expression of cDNAs encoding methionine-sensitive and -insensitive homocysteine S- methyltransferases from Arabidopsis.

P83840	VITA_VIOAR	Vitri peptide A	14987049	Cytotoxic cyclotides from Viola tricolor.

Q23985	DTX_DROME	Protein deltex	11719214	Novel Notch alleles reveal a Deltex-dependent pathway repressing neural fate.

P08581	MET_HUMAN	Hepatocyte growth factor receptor	1846706	Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product.

P47045	TIM54_YEAST	Mitochondrial import inner membrane translocase subunit TIM54	10637294	Tim18p is a new component of the Tim54p-Tim22p translocon in the mitochondrial inner membrane.

Q8T7K0	ALIX_DICDI	ALG-2 interacting protein X	15757670	Dictyostelium discoideum requires an Alix/AIP1 homolog, DdAlix, for morphogenesis in alkaline environments.

Q9HCK5	AGO4_HUMAN	Protein argonaute-4	18771919	Importance of translation and nonnucleolytic ago proteins for on- target RNA interference.

Q10187	UCP6_SCHPO	UBA domain-containing protein 6	11584278	Proteins containing the UBA domain are able to bind to multi- ubiquitin chains.

Q5YDB5	CPL2_ARATH	RNA polymerase II C-terminal domain phosphatase-like 2	18506580	The Arabidopsis thaliana carboxyl-terminal domain phosphatase-like 2 regulates plant growth, stress and auxin responses.

P61088	UBE2N_HUMAN	Ubiquitin-conjugating enzyme E2 N	8902611	Cloning and expression of cDNA encoding a human ubiquitin-conjugating enzyme similar to the Drosophila bendless gene product.

Q9P885	GGPPS_RHIRA	Geranylgeranyl pyrophosphate synthase	12695851	Expression of the carG gene, encoding geranylgeranyl pyrophosphate synthase, is up-regulated by blue light in Mucor circinelloides.

P15291	B4GT1_HUMAN	Beta-1,4-galactosyltransferase 1	7540104	Analysis of the sequences of human beta-1,4-galactosyltransferase cDNA clones.

P13221	AATC_RAT	Aspartate aminotransferase, cytoplasmic	3182856	Nucleotide sequence and glucocorticoid regulation of the mRNAs for the isoenzymes of rat aspartate aminotransferase.

O95714	HERC2_HUMAN	E3 ubiquitin-protein ligase HERC2	9949213	The ancestral gene for transcribed, low-copy repeats in the Prader- Willi/Angelman region encodes a large protein implicated in protein trafficking, which is deficient in mice with neuromuscular and spermiogenic abnormalities.

Q15233	NONO_HUMAN	Non-POU domain-containing octamer-binding protein	8371983	Purification and cDNA cloning of HeLa cell p54nrb, a nuclear protein with two RNA recognition motifs and extensive homology to human splicing factor PSF and Drosophila NONA/BJ6.

Q9NPI6	DCP1A_HUMAN	mRNA-decapping enzyme 1A	16364915	Multiple processing body factors and the ARE binding protein TTP activate mRNA decapping.

P43404	ZAP70_MOUSE	Tyrosine-protein kinase ZAP-70	9208839	A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development.

P53550	DCP2_YEAST	mRNA-decapping enzyme subunit 2	12730603	Decapping and decay of messenger RNA occur in cytoplasmic processing bodies.

Q05513	KPCZ_HUMAN	Protein kinase C zeta type	12893243	Centaurin-alpha(1) associates with and is phosphorylated by isoforms of protein kinase C.

P84868	DEF_VIGUS	Defensin-like protein	15949629	Sesquin, a potent defensin-like antimicrobial peptide from ground beans with inhibitory activities toward tumor cells and HIV-1 reverse transcriptase.

Q9D074	MGRN1_MOUSE	E3 ubiquitin-protein ligase MGRN1	19524515	Functional depletion of mahogunin by cytosolically exposed prion protein contributes to neurodegeneration.

P84744	KAX95_BUTOC	Potassium channel toxin alpha-KTx 9.5	15165720	Kbot1, a three disulfide bridges toxin from Buthus occitanus tunetanus venom highly active on both SK and Kv channels.

Q16594	TAF9_HUMAN	Transcription initiation factor TFIID subunit 9	7667268	Evolutionary conservation of human TATA-binding-polypeptide- associated factors TAFII31 and TAFII80 and interactions of TAFII80 with other TAFs and with general transcription factors.

Q6AYY8	ACATN_RAT	Acetyl-coenzyme A transporter 1	10965123	cDNA cloning of putative rat acetyl-CoA transporter and its expression pattern in brain.

Q9ZR72	AB1B_ARATH	ABC transporter B family member 1	9761790	Involvement of an ABC transporter in a developmental pathway regulating hypocotyl cell elongation in the light.

O60259	KLK8_HUMAN	Kallikrein-8	16337200	Biochemical characterization of human kallikrein 8 and its possible involvement in the degradation of extracellular matrix proteins.

Q922G7	TEKT2_MOUSE	Tektin-2	15340058	Mice deficient in the axonemal protein tektin-t exhibit male infertility and immotile-cilium syndrome due to impaired inner arm dynein function.

P97536	CAND1_RAT	Cullin-associated NEDD8-dissociated protein 1	10567521	TATA-Binding protein-interacting protein 120, TIP120, stimulates three classes of eukaryotic transcription via a unique mechanism.

O95865	DDAH2_HUMAN	N(G),N(G)-dimethylarginine dimethylaminohydrolase 2	10493931	Identification of two human dimethylarginine dimethylaminohydrolases with distinct tissue distributions and homology with microbial arginine deiminases.

P07390	PT494_YEAST	COX3 mRNA-specific translational activator PET494	8389363	COX3 mRNA-specific translational activator proteins are associated with the inner mitochondrial membrane in Saccharomyces cerevisiae.

Q02753	RL21A_YEAST	60S ribosomal protein L21-A	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q62658	FKB1A_RAT	Peptidyl-prolyl cis-trans isomerase FKBP1A	7518616	Specific interaction of type I receptors of the TGF-beta family with the immunophilin FKBP-12.

O43734	CIKS_HUMAN	Adapter protein CIKS	10962033	CIKS, a connection to Ikappa B kinase and stress-activated protein kinase.

Q10282	GBB_SCHPO	Guanine nucleotide-binding protein subunit beta	8804400	The G protein beta subunit Gpb1 of Schizosaccharomyces pombe is a negative regulator of sexual development.

Q9JMH6	TRXR1_MOUSE	Thioredoxin reductase 1, cytoplasmic	10721726	Molecular cloning of mouse thioredoxin reductases.

Q02283	HAT5_ARATH	Homeobox-leucine zipper protein HAT5	8253077	The Athb-1 and -2 HD-Zip domains homodimerize forming complexes of different DNA binding specificities.

P24280	SEC14_YEAST	SEC14 cytosolic factor	2466847	The Saccharomyces cerevisiae SEC14 gene encodes a cytosolic factor that is required for transport of secretory proteins from the yeast Golgi complex.

Q9SAZ5	AHP3_ARATH	Histidine-containing phosphotransfer protein 3	10050311	Histidine-containing phosphotransfer (HPt) signal transducers implicated in His-to-Asp phosphorelay in Arabidopsis.

O70373	XIRP1_MOUSE	Xin actin-binding repeat-containing protein 1	10021346	Requirement of a novel gene, Xin, in cardiac morphogenesis.

P52960	PIP2_YEAST	Peroxisome proliferation transcriptional regulator	8670793	Pip2p: a transcriptional regulator of peroxisome proliferation in the yeast Saccharomyces cerevisiae.

Q9HCN6	GPVI_HUMAN	Platelet glycoprotein VI	9295288	A novel association of Fc receptor gamma-chain with glycoprotein VI and their co-expression as a collagen receptor in human platelets.

Q10434	CAPZA_SCHPO	F-actin-capping protein subunit alpha	15743909	Profilin-mediated competition between capping protein and formin Cdc12p during cytokinesis in fission yeast.

Q9VQ79	AIFM1_DROME	Putative apoptosis-inducing factor 1, mitochondrial	18309327	The molecular archaeology of a mitochondrial death effector: AIF in Drosophila.

P34231	YKS7_YEAST	Uncharacterized protein YKL187C	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q04659	CSM3_YEAST	Chromosome segregation in meiosis protein 3	14742714	Identification of protein complexes required for efficient sister chromatid cohesion.

Q04053	SNX41_YEAST	Sorting nexin-41	12554655	Retromer and the sorting nexins Snx4/41/42 mediate distinct retrieval pathways from yeast endosomes.

P32485	HOG1_YEAST	Mitogen-activated protein kinase HOG1	10805732	Rck2 kinase is a substrate for the osmotic stress-activated mitogen- activated protein kinase Hog1.

Q08231	THP1_YEAST	Nuclear mRNA export protein THP1	11139493	A new hyperrecombination mutation identifies a novel yeast gene, THP1, connecting transcription elongation with mitotic recombination.

Q16769	QPCT_HUMAN	Glutaminyl-peptide cyclotransferase	7999256	Molecular cloning, sequence analysis and expression of human pituitary glutaminyl cyclase.

P11168	GTR2_HUMAN	Solute carrier family 2, facilitated glucose transporter member 2	8027028	A mutation in the Glut2 glucose transporter gene of a diabetic patient abolishes transport activity.

Q96CW5	GCP3_HUMAN	Gamma-tubulin complex component 3	9566969	Characterization of the human homologue of the yeast spc98p and its association with gamma-tubulin.

Q99959	PKP2_HUMAN	Plakophilin-2	8922383	Plakophilins 2a and 2b: constitutive proteins of dual location in the karyoplasm and the desmosomal plaque.

P42737	CAH2_ARATH	Carbonic anhydrase 2, chloroplastic	7520589	Characterization and expression of two cDNAs encoding carbonic anhydrase in Arabidopsis thaliana.

Q10359	GMH3_SCHPO	Alpha-1,2-galactosyltransferase gmh3	9839953	Differences in in vivo acceptor specificity of two galactosyltransferases, the gmh3+ and gma12+ gene products from Schizosaccharomyces pombe.

P43628	KI2L3_HUMAN	Killer cell immunoglobulin-like receptor 2DL3	7749980	Molecular clones of the p58 NK cell receptor reveal immunoglobulin- related molecules with diversity in both the extra- and intracellular domains.

P08622	DNAJ_ECOLI	Chaperone protein dnaJ	9860950	Interaction of the Hsp70 molecular chaperone, DnaK, with its cochaperone DnaJ.

Q9BXS0	COPA1_HUMAN	Collagen alpha-1(XXV) chain	11927537	CLAC: a novel Alzheimer amyloid plaque component derived from a transmembrane precursor, CLAC-P/collagen type XXV.

P87050	CDR2_SCHPO	Mitosis inducer protein kinase cdr2	9843572	The protein kinase Cdr2, related to Nim1/Cdr1 mitotic inducer, regulates the onset of mitosis in fission yeast.

Q99MI1	RB6I2_MOUSE	ELKS/Rab6-interacting/CAST family member 1	11929610	Characterization of novel Rab6-interacting proteins involved in endosome-to-TGN transport.

Q13228	SBP1_HUMAN	Selenium-binding protein 1	9027582	Isolation, characterization, and chromosomal mapping of a novel cDNA clone encoding human selenium binding protein.

P53223	CAX4_YEAST	Dolichyldiphosphatase	11504728	The CWH8 gene encodes a dolichyl pyrophosphate phosphatase with a luminally oriented active site in the endoplasmic reticulum of Saccharomyces cerevisiae.

Q9NQ66	PLCB1_HUMAN	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1	11118617	Cloning and characterization of the human phosphoinositide-specific phospholipase C-beta 1 (PLCbeta1).

Q9Y2C4	EXOG_HUMAN	Nuclease EXOG, mitochondrial	10231028	Characterization of a 1200-kb genomic segment of chromosome 3p22- p21.3.

P24626	CHI3_ORYSJ	Chitinase 3	12834284	Structure, heterologous expression, and properties of rice (Oryza sativa L.) family 19 chitinases.

O74531	POF7_SCHPO	F-box protein pof7	15147268	Molecular interactions of fission yeast Skp1 and its role in the DNA damage checkpoint.

P93022	ARFG_ARATH	Auxin response factor 7	17259263	ARF7 and ARF19 regulate lateral root formation via direct activation of LBD/ASL genes in Arabidopsis.

P32454	APE2_YEAST	Aminopeptidase 2, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q8NEZ5	FBX22_HUMAN	F-box only protein 22	10531035	Identification of a family of human F-box proteins.

P46467	VPS4B_MOUSE	Vacuolar protein sorting-associated protein 4B	10637304	ATPase-defective mammalian VPS4 localizes to aberrant endosomes and impairs cholesterol trafficking.

Q8BW96	KCC1D_MOUSE	Calcium/calmodulin-dependent protein kinase type 1D	14980499	Effects of PU.1-induced mouse calcium-calmodulin-dependent kinase I- like kinase (CKLiK) on apoptosis of murine erythroleukemia cells.

P41934	HM18_CAEEL	Homeobox protein ceh-18	7958868	Targeted mutations in the Caenorhabditis elegans POU homeo box gene ceh-18 cause defects in oocyte cell cycle arrest, gonad migration, and epidermal differentiation.

Q9JI15	CK2N1_RAT	Calcium/calmodulin-dependent protein kinase II inhibitor 1	11182241	Calcium/calmodulin-dependent protein kinase II inhibitor protein: localization of isoforms in rat brain.

P32603	SPR1_YEAST	Sporulation-specific glucan 1,3-beta-glucosidase	8419289	The Saccharomyces cerevisiae SPR1 gene encodes a sporulation-specific exo-1,3-beta-glucanase which contributes to ascospore thermoresistance.

O94318	VPS20_SCHPO	Vacuolar protein sorting-associated protein 20	17660439	Essential roles of class E Vps proteins for sorting into multivesicular bodies in Schizosaccharomyces pombe.

O94478	MU137_SCHPO	Meiotically up-regulated gene 137 protein	12161753	The transcriptional program of meiosis and sporulation in fission yeast.

Q13887	KLF5_HUMAN	Krueppel-like factor 5	8479902	cDNA cloning and transcriptional properties of a novel GC box-binding protein, BTEB2.

Q9Y6N9	USH1C_HUMAN	Harmonin	11311560	Interaction of MCC2, a novel homologue of MCC tumor suppressor, with PDZ-domain protein AIE-75.

Q8VHX2	EDAD_MOUSE	Ectodysplasin-A receptor-associated adapter protein	11780064	Gene defect in ectodermal dysplasia implicates a DEATH domain adapter in development.

Q9H161	ALX4_HUMAN	Homeobox protein aristaless-like 4	11137991	Haploinsufficiency of the human homeobox gene ALX4 causes skull ossification defects.

P40512	CSN11_YEAST	Cop9 signalosome complex subunit 11	12446563	COP9 signalosome components play a role in the mating pheromone response of S. cerevisiae.

Q96NA2	RILP_HUMAN	Rab-interacting lysosomal protein	11179213	Rab-interacting lysosomal protein (RILP): the Rab7 effector required for transport to lysosomes.

P06773	DCTD_YEAST	Deoxycytidylate deaminase	3023902	Sequence and expression of the dCMP deaminase gene (DCD1) of Saccharomyces cerevisiae.

Q924C6	LOXL4_MOUSE	Lysyl oxidase homolog 4	11292829	Molecular cloning and biological activity of a novel lysyl oxidase- related gene expressed in cartilage.

Q1XH17	TRI72_MOUSE	Tripartite motif-containing protein 72	19029292	MG53 regulates membrane budding and exocytosis in muscle cells.

Q03262	PGM3_YEAST	Phosphoglucomutase YMR278W	18042468	Molecular characterization reveals that YMR278w encoded protein is environmental stress response homologue of Saccharomyces cerevisiae PGM2.

Q8IYB8	SUV3_HUMAN	ATP-dependent RNA helicase SUPV3L1, mitochondrial	12466530	Localisation of the human hSuv3p helicase in the mitochondrial matrix and its preferential unwinding of dsDNA.

Q9Z0J4	NOS1_MOUSE	Nitric oxide synthase, brain	17452640	Physical interaction between the serotonin transporter and neuronal nitric oxide synthase underlies reciprocal modulation of their activity.

Q9ER97	NGB_MOUSE	Neuroglobin	11029004	A vertebrate globin expressed in the brain.

Q39016	CDPKB_ARATH	Calcium-dependent protein kinase 11	8078458	Two genes that encode Ca(2+)-dependent protein kinases are induced by drought and high-salt stresses in Arabidopsis thaliana.

Q8BHC1	RB39B_MOUSE	Ras-related protein Rab-39B	20159109	Mutations in the small GTPase gene RAB39B are responsible for X- linked mental retardation associated with autism, epilepsy, and macrocephaly.

P20095	PRP2_YEAST	Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2	8943336	Spliceosome activation by PRP2 ATPase prior to the first transesterification reaction of pre-mRNA splicing.

Q9Z1G4	VPP1_MOUSE	V-type proton ATPase 116 kDa subunit a isoform 1	10722719	Three subunit a isoforms of mouse vacuolar H+-ATPase. Preferential expression of the a3 isoform during osteoclast differentiation.

Q09736	CP51_SCHPO	Lanosterol 14-alpha demethylase erg11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P64461	LSRG_ECOLI	Autoinducer 2-degrading protein lsrG	17274596	Phosphorylation and processing of the quorum-sensing molecule autoinducer-2 in enteric bacteria.

P25300	BUD5_YEAST	Bud site selection protein 5	11313501	A GDP/GTP exchange factor involved in linking a spatial landmark to cell polarity.

P09083	GSBN_DROME	Protein gooseberry-neuro	3123319	Structure of two genes at the gooseberry locus related to the paired gene and their spatial expression during Drosophila embryogenesis.

Q10573	LIN25_CAEEL	Protein lin-25	11063686	Caenorhabditis elegans lin-25: a study of its role in multiple cell fate specification events involving ras and the identification and characterization of evolutionarily conserved domains.

Q38931	FKB70_ARATH	70 kDa peptidyl-prolyl isomerase	8914512	Novel structure of a high molecular weight FK506 binding protein from Arabidopsis thaliana.

P34111	TFC3_YEAST	Transcription factor tau 138 kDa subunit	2180956	Purification and characterization of Saccharomyces cerevisiae transcription factor TFIIIC. Polypeptide composition defined with polyclonal antibodies.

Q13838	UAP56_HUMAN	Spliceosome RNA helicase BAT1	15833825	Linking transcriptional elongation and messenger RNA export to metastatic breast cancers.

Q9H3H1	MOD5_HUMAN	tRNA dimethylallyltransferase, mitochondrial	11111046	Cloning of a human tRNA isopentenyl transferase.

P25582	SPB1_YEAST	AdoMet-dependent rRNA methyltransferase SPB1	14636587	Functional redundancy of Spb1p and a snR52-dependent mechanism for the 2'-O-ribose methylation of a conserved rRNA position in yeast.

Q91399	ID3A_XENLA	DNA-binding protein inhibitor ID-3-A	18721802	Hairy2-Id3 interactions play an essential role in Xenopus neural crest progenitor specification.

Q09328	MGT5A_HUMAN	Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A	8292036	cDNA cloning and chromosomal mapping of human N- acetylglucosaminyltransferase V+.

A9LMC0	DPF3_DANRE	Zinc finger protein DPF3	18765789	Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex.

Q8VZW1	NIP11_ARATH	Aquaporin NIP1-1	9276952	The major intrinsic protein family of Arabidopsis has 23 members that form three distinct groups with functional aquaporins in each group.

P16435	NCPR_HUMAN	NADPH--cytochrome P450 reductase	10048323	Crystal structure of the FMN-binding domain of human cytochrome P450 reductase at 1.93 A resolution.

Q9Z288	GCM1_RAT	Chorion-specific transcription factor GCMa	9770492	Isolation and characterization of mammalian homologs of the Drosophila gene glial cells missing.

P45983	MK08_HUMAN	Mitogen-activated protein kinase 8	8654373	Selective interaction of JNK protein kinase isoforms with transcription factors.

P18510	IL1RA_HUMAN	Interleukin-1 receptor antagonist protein	1385987	Cloning and chromosome mapping of the human interleukin-1 receptor antagonist gene.

Q9VCI3	LSD1_DROME	Lipid storage droplets surface-binding protein 1	12077142	Functional conservation for lipid storage droplet association among Perilipin, ADRP, and TIP47 (PAT)-related proteins in mammals, Drosophila, and Dictyostelium.

O14966	RAB7L_HUMAN	Ras-related protein Rab-7L1	9284931	Cloning and chromosome assignment to 1q32 of a human cDNA (RAB7L1) encoding a small GTP-binding protein, a member of the RAS superfamily.

Q8VEE1	LMCD1_MOUSE	LIM and cysteine-rich domains protein 1	20026769	LIM and cysteine-rich domains 1 regulates cardiac hypertrophy by targeting calcineurin/nuclear factor of activated T cells signaling.

P0ACB4	HEMG_ECOLI	Protoporphyrinogen IX dehydrogenase [menaquinone]	7916647	Nucleotide sequence of the hemG gene involved in the protoporphyrinogen oxidase activity of Escherichia coli K12.

Q12143	NSL1_YEAST	Kinetochore-associated protein NSL1	14633972	Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes.

Q19420	IMPA1_CAEEL	Inositol monophosphatase ttx-7	17158747	Inositol monophosphatase regulates localization of synaptic components and behavior in the mature nervous system of C. elegans.

P42759	ERD10_ARATH	Dehydrin ERD10	7579189	Structure and organization of two closely related low-temperature- induced dhn/lea/rab-like genes in Arabidopsis thaliana L. Heynh.

P70269	CATE_MOUSE	Cathepsin E	1601038	Antigen processing for presentation by class II major histocompatibility complex requires cleavage by cathepsin E.

Q02648	TRM44_YEAST	tRNA (uracil-O(2)-)-methyltransferase	18025252	Identification of yeast tRNA Um(44) 2'-O-methyltransferase (Trm44) and demonstration of a Trm44 role in sustaining levels of specific tRNA(Ser) species.

P38274	HSL7_YEAST	Protein arginine N-methyltransferase HSL7	8647431	A search for proteins that interact genetically with histone H3 and H4 amino termini uncovers novel regulators of the Swe1 kinase in Saccharomyces cerevisiae.

P21771	RT28_YEAST	37S ribosomal protein S28, mitochondrial	11278769	Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues.

Q8VCH7	RDH10_MOUSE	Retinol dehydrogenase 10	17473173	RDH10 is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development.

Q6EVK6	BRM_ARATH	ATP-dependent helicase BRM	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

P53730	ALG12_YEAST	Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase	10336995	Ordered assembly of the asymmetrically branched lipid-linked oligosaccharide in the endoplasmic reticulum is ensured by the substrate specificity of the individual glycosyltransferases.

Q9FHA7	HEC1_ARATH	Transcription factor HEC1	17855426	The HECATE genes regulate female reproductive tract development in Arabidopsis thaliana.

Q6DGL6	SOX1A_DANRE	Transcription factor Sox-1a	16408288	Comparative genomic and expression analysis of group B1 sox genes in zebrafish indicates their diversification during vertebrate evolution.

P42357	HUTH_HUMAN	Histidine ammonia-lyase	15806399	Molecular characterization of histidinemia: identification of four missense mutations in the histidase gene.

P19838	NFKB1_HUMAN	Nuclear factor NF-kappa-B p105 subunit	1992489	Cloning of the DNA-binding subunit of human nuclear factor kappa B: the level of its mRNA is strongly regulated by phorbol ester or tumor necrosis factor alpha.

P39406	RSMC_ECOLI	Ribosomal RNA small subunit methyltransferase C	9873033	Purification, cloning, and characterization of the 16S RNA m2G1207 methyltransferase from Escherichia coli.

O95751	LDOC1_HUMAN	Protein LDOC1	10403563	Identification of a novel gene, LDOC1, down-regulated in cancer cell lines.

Q16663	CCL15_HUMAN	C-C motif chemokine 15	9600961	HCC-2, a human chemokine: gene structure, expression pattern, and biological activity.

Q9VW47	MED12_DROME	Mediator of RNA polymerase II transcription subunit 12	12835386	Two subunits of the Drosophila mediator complex act together to control cell affinity.

P18627	LAG3_HUMAN	Lymphocyte activation gene 3 protein	1692078	LAG-3, a novel lymphocyte activation gene closely related to CD4.

P40056	GET2_YEAST	Golgi to ER traffic protein 2	18724936	The GET complex mediates insertion of tail-anchored proteins into the ER membrane.

Q24212	STNB_DROME	Protein stoned-B	11160392	Interaction of stoned and synaptotagmin in synaptic vesicle endocytosis.

P48423	GAP1_DROME	GTPase-activating protein	1547500	A putative Ras GTPase activating protein acts as a negative regulator of signaling by the Sevenless receptor tyrosine kinase.

Q9UT12	YLW2_SCHPO	Uncharacterized protein P8A3.02c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P32970	CD70_HUMAN	CD70 antigen	8387892	Molecular and biological characterization of a ligand for CD27 defines a new family of cytokines with homology to tumor necrosis factor.

Q9JHX3	IL21R_MOUSE	Interleukin-21 receptor	11081504	Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function.

O42478	TLE4_XENLA	Transducin-like enhancer protein 4	9783587	The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors.

P49415	SDC_DROME	Syndecan	14761655	Heparan sulfate proteoglycan syndecan promotes axonal and myotube guidance by slit/robo signaling.

P63147	UBE2B_MOUSE	Ubiquitin-conjugating enzyme E2 B	14585983	Female lethality and apoptosis of spermatocytes in mice lacking the UBR2 ubiquitin ligase of the N-end rule pathway.

Q9Y266	NUDC_HUMAN	Nuclear migration protein nudC	10210332	A homolog of the fungal nuclear migration gene nudC is involved in normal and malignant human hematopoiesis.

P38251	RFC5_YEAST	Replication factor C subunit 5	10913172	Rfc5, in cooperation with rad24, controls DNA damage checkpoints throughout the cell cycle in Saccharomyces cerevisiae.

O43187	IRAK2_HUMAN	Interleukin-1 receptor-associated kinase-like 2	9374458	IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling.

Q8I7Z8	HAM_DROME	Transcription factor hamlet	15075290	Conversion of neurons and glia to external-cell fates in the external sensory organs of Drosophila hamlet mutants by a cousin-cousin cell- type respecification.

P24821	TENA_HUMAN	Tenascin	1704365	The complete cDNA sequence of human hexabrachion (Tenascin). A multidomain protein containing unique epidermal growth factor repeats.

Q700C7	SPCH_ARATH	Transcription factor SPEECHLESS	17183265	Transcription factor control of asymmetric cell divisions that establish the stomatal lineage.

P53196	RPN14_YEAST	26S proteasome regulatory subunit RPN14	17499717	Rpn13p and Rpn14p are involved in the recognition of ubiquitinated Gcn4p by the 26S proteasome.

Q16552	IL17_HUMAN	Interleukin-17A	7499828	Human IL-17: a novel cytokine derived from T cells.

P51678	CCR3_MOUSE	Probable C-C chemokine receptor type 3	7594543	Molecular characterization of two murine eosinophil beta chemokine receptors.

Q99643	C560_HUMAN	Succinate dehydrogenase cytochrome b560 subunit, mitochondrial	9533030	Cytochrome b in human complex II (succinate-ubiquinone oxidoreductase): cDNA cloning of the components in liver mitochondria and chromosome assignment of the genes for the large (SDHC) and small (SDHD) subunits to 1q21 and 11q23.

O95907	MOT3_HUMAN	Monocarboxylate transporter 3	10493836	Cloning of the human monocarboxylate transporter MCT3 gene: localization to chromosome 22q12.3-q13.2.

O08781	ZMAT3_RAT	Zinc finger matrin-type protein 3	9250682	A novel p53-inducible gene, PAG608, encodes a nuclear zinc finger protein whose overexpression promotes apoptosis.

P38144	ISW1_YEAST	ISWI chromatin-remodeling complex ATPase ISW1	11238381	In vivo chromatin remodeling by yeast ISWI homologs Isw1p and Isw2p.

P41808	SMK1_YEAST	Sporulation-specific mitogen-activated protein kinase SMK1	7958885	SMK1, a developmentally regulated MAP kinase, is required for spore wall assembly in Saccharomyces cerevisiae.

Q92886	NGN1_HUMAN	Neurogenin-1	8816493	NeuroD2 and neuroD3: distinct expression patterns and transcriptional activation potentials within the neuroD gene family.

Q62920	PDLI5_RAT	PDZ and LIM domain protein 5	8940095	Protein-protein interaction of zinc finger LIM domains with protein kinase C.

P40012	PPOX_YEAST	Protoporphyrinogen oxidase	7798202	Purification and properties of protoporphyrinogen oxidase from the yeast Saccharomyces cerevisiae. Mitochondrial location and evidence for a precursor form of the protein.

B7ZR65	SOX9A_XENLA	Transcription factor Sox-9-A	16943273	Functional analysis of Sox8 during neural crest development in Xenopus.

Q800K6	TOB1A_XENLA	DNA topoisomerase 2-binding protein 1-A	16782873	The N-terminal noncatalytic region of Xenopus RecQ4 is required for chromatin binding of DNA polymerase alpha in the initiation of DNA replication.

Q92499	DDX1_HUMAN	ATP-dependent RNA helicase DDX1	7689221	Amplification of a DEAD box protein gene in retinoblastoma cell lines.

P16104	H2AX_HUMAN	Histone H2A.x	10959836	A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage.

P41912	ERFD_YEAST	Ras modification protein ERF4	12193598	Identification of a Ras palmitoyltransferase in Saccharomyces cerevisiae.

Q9Z0F3	B2L10_MOUSE	Bcl-2-like protein 10	9878060	Boo, a novel negative regulator of cell death, interacts with Apaf- 1.

P41498	PPAC_RAT	Low molecular weight phosphotyrosine protein phosphatase	11971983	Tyrosine phosphorylation regulates alpha II spectrin cleavage by calpain.

O60858	TRI13_HUMAN	E3 ubiquitin-protein ligase TRIM13	9599022	A cosmid and cDNA fine physical map of a human chromosome 13q14 region frequently lost in B-cell chronic lymphocytic leukemia and identification of a new putative tumor suppressor gene, Leu5.

Q63564	SV2B_RAT	Synaptic vesicle glycoprotein 2B	7681585	Brain contains two forms of synaptic vesicle protein 2.

Q920R3	FADS1_RAT	Fatty acid desaturase 1	11414679	Fatty acid Delta(5)-desaturase mRNA is regulated by dietary vitamin A and exogenous retinoic acid in liver of adult rats.

Q2WG76	RIPP2_MOUSE	Protein ripply2	16326386	Groucho-associated transcriptional repressor ripply1 is required for proper transition from the presomitic mesoderm to somites.

Q7T3B2	HRG1A_DANRE	Heme transporter hrg1-A	18418376	Haem homeostasis is regulated by the conserved and concerted functions of HRG-1 proteins.

P52744	ZN138_HUMAN	Zinc finger protein 138	7557990	Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders.

P14605	CYAA_SCHPO	Adenylate cyclase	16489217	Schizosaccharomyces pombe Git1 is a C2-domain protein required for glucose activation of adenylate cyclase.

Q9C5W3	NADK2_ARATH	NAD kinase 2, chloroplastic	15247403	Cloning and characterization of two NAD kinases from Arabidopsis. Identification of a calmodulin binding isoform.

P06101	CDC37_YEAST	Hsp90 co-chaperone Cdc37	14562095	Global analysis of protein localization in budding yeast.

P47793	WNT4A_DANRE	Protein Wnt-4a	8541205	Wnt4 affects morphogenesis when misexpressed in the zebrafish embryo.

Q04172	SHE9_YEAST	Sensitive to high expression protein 9, mitochondrial	11907266	Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae.

P28335	5HT2C_HUMAN	5-hydroxytryptamine receptor 2C	16319069	A beta-arrestin binding determinant common to the second intracellular loops of rhodopsin family G protein-coupled receptors.

Q9HC16	ABC3G_HUMAN	DNA dC->dU-editing enzyme APOBEC-3G	11863358	An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22.

Q05397	FAK1_HUMAN	Focal adhesion kinase 1	8422239	Expression of an N-terminally truncated form of human focal adhesion kinase in brain.

P39748	FEN1_HUMAN	Flap endonuclease 1	8007985	Structural and functional conservation of the human homolog of the Schizosaccharomyces pombe rad2 gene, which is required for chromosome segregation and recovery from DNA damage.

Q8RY29	ADPG2_ARATH	Polygalacturonase ADPG2	19168715	ARABIDOPSIS DEHISCENCE ZONE POLYGALACTURONASE1 (ADPG1), ADPG2, and QUARTET2 are polygalacturonases required for cell separation during reproductive development in Arabidopsis.

Q9SKB3	PARG1_ARATH	Poly(ADP-ribose) glycohydrolase 1	12110167	tej defines a role for poly(ADP-ribosyl)ation in establishing period length of the arabidopsis circadian oscillator.

Q15691	MARE1_HUMAN	Microtubule-associated protein RP/EB family member 1	15631994	CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex.

Q12009	TRMB_YEAST	tRNA (guanine-N(7)-)-methyltransferase	17382321	RNA recognition mechanism of eukaryote tRNA (m7G46) methyltransferase (Trm8-Trm82 complex).

Q9ZU11	ATB15_ARATH	Homeobox-leucine zipper protein ATHB-15	17237362	Overexpression of miR165 affects apical meristem formation, organ polarity establishment and vascular development in Arabidopsis.

Q9NS56	TOPRS_HUMAN	E3 ubiquitin-protein ligase Topors	11278651	Cloning and characterization of LUN, a novel RING-finger protein that is highly expressed in lung and specifically binds to a palindromic sequence.

P53954	ALG11_YEAST	Alpha-1,2-mannosyltransferase ALG11	15044395	Physical interactions between the Alg1, Alg2, and Alg11 mannosyltransferases of the endoplasmic reticulum.

Q9LM76	PUB44_ARATH	U-box domain-containing protein 44	19309463	Identification of a novel E3 ubiquitin ligase that is required for suppression of premature senescence in Arabidopsis.

O62090	PRY1_CAEEL	Axin-like protein pry-1	17213328	Axon guidance genes identified in a large-scale RNAi screen using the RNAi-hypersensitive Caenorhabditis elegans strain nre-1(hd20) lin- 15b(hd126).

Q9UEU5	GAGE8_HUMAN	G antigen 8	10397259	Characterization of the GAGE genes that are expressed in various human cancers and in normal testis.

P40213	RS16_YEAST	40S ribosomal protein S16	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

P09493	TPM1_HUMAN	Tropomyosin alpha-1 chain	3336363	Human hTM alpha gene: expression in muscle and nonmuscle tissue.

P04688	TBA1_SCHPO	Tubulin alpha-1 chain	6327053	Identification of the pleiotropic cell division cycle gene NDA2 as one of two different alpha-tubulin genes in Schizosaccharomyces pombe.

Q8GY23	UPL1_ARATH	E3 ubiquitin-protein ligase UPL1	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

P38727	YHE4_YEAST	DUP240 protein YHL044W	12101299	Functional analysis of the Saccharomyces cerevisiae DUP240 multigene family reveals membrane-associated proteins that are not essential for cell viability.

P13839	SIAL_RAT	Bone sialoprotein 2	3198635	The primary structure of a cell-binding bone sialoprotein.

P58951	GR22A_DROME	Putative gustatory receptor 22a	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

Q96QS1	TSN32_HUMAN	Tetraspanin-32	10950922	Phemx, a novel mouse gene expressed in hematopoietic cells maps to the imprinted cluster on distal chromosome 7.

Q9W252	RAD50_DROME	DNA repair protein RAD50	15296753	The Drosophila Mre11/Rad50 complex is required to prevent both telomeric fusion and chromosome breakage.

Q22036	CAN5_CAEEL	Calpain-5	8887539	The tra-3 sex determination gene of Caenorhabditis elegans encodes a member of the calpain regulatory protease family.

Q8WYA6	CTBL1_HUMAN	Beta-catenin-like protein 1	12659813	Sequence, gene structure, and expression pattern of CTNNBL1, a minor- class intron-containing gene - evidence for a role in apoptosis.

Q9Z301	PER2_RAT	Period circadian protein homolog 2	11112428	Molecular characterization and nuclear localization of rat timeless- like gene product.

Q9STR4	1A17_ARATH	1-aminocyclopropane-1-carboxylate synthase 7	12968022	Biochemical diversity among the 1-amino-cyclopropane-1-carboxylate synthase isozymes encoded by the Arabidopsis gene family.

Q96DZ1	ERLEC_HUMAN	Endoplasmic reticulum lectin 1	18264092	OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD.

Q9UJ41	RABX5_HUMAN	Rab5 GDP/GTP exchange factor	17450153	Structural basis for Rab GTPase activation by VPS9 domain exchange factors.

Q8L6Y1	UBP14_ARATH	Ubiquitin carboxyl-terminal hydrolase 14	11576424	The ubiquitin-specific protease UBP14 is essential for early embryo development in Arabidopsis thaliana.

Q9I925	FUCL7_ANGJA	Fucolectin-7	10924498	Multiplicity, structures, and endocrine and exocrine natures of eel fucose-binding lectins.

P48637	GSHB_HUMAN	Glutathione synthetase	10369661	Molecular basis of glutathione synthetase deficiency and a rare gene permutation event.

O14815	CAN9_HUMAN	Calpain-9	9524069	Molecular cloning and characterization of a novel tissue-specific calpain predominantly expressed in the digestive tract.

Q8BZL1	NEUR4_MOUSE	Sialidase-4	14637003	Identification and expression of Neu4, a novel murine sialidase.

Q7ZWK8	OTOP1_DANRE	Otopetrin-1	15581873	Otopetrin 1 is required for otolith formation in the zebrafish Danio rerio.

Q8WW43	APH1B_HUMAN	Gamma-secretase subunit APH-1B	12297508	Mammalian APH-1 interacts with presenilin and nicastrin and is required for intramembrane proteolysis of amyloid-beta precursor protein and Notch.

P62195	PRS8_HUMAN	26S protease regulatory subunit 8	7729537	cDNA cloning of a new putative ATPase subunit p45 of the human 26S proteasome, a homolog of yeast transcriptional factor Sug1p.

Q9GZY6	NTAL_HUMAN	Linker for activation of T-cells family member 2	12514734	LAB: a new membrane-associated adaptor molecule in B cell activation.

Q3E764	TMA7_YEAST	Translation machinery-associated protein 7	14562095	Global analysis of protein localization in budding yeast.

P62907	RL10A_RAT	60S ribosomal protein L10a	8607874	The primary structure of rat ribosomal protein L10a.

Q9FQ04	XRN4_ARATH	5'-3' exoribonuclease 4	17085683	The exoribonuclease XRN4 is a component of the ethylene response pathway in Arabidopsis.

P63166	SUMO1_MOUSE	Small ubiquitin-related modifier 1	15767674	Ikaros SUMOylation: switching out of repression.

Q9BQA5	HINFP_HUMAN	Histone H4 transcription factor	11553631	Involvement of a novel zinc finger protein, MIZF, in transcriptional repression by interacting with a methyl-CpG-binding protein, MBD2.

Q9P7N5	CD123_SCHPO	Cell division cycle protein 123	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O14543	SOCS3_HUMAN	Suppressor of cytokine signaling 3	9266833	Cloning and functional analysis of new members of STAT induced STAT inhibitor (SSI) family: SSI-2 and SSI-3.

Q9SYT0	ANXD1_ARATH	Annexin D1	16153598	Peroxidase activity of annexin 1 from Arabidopsis thaliana.

Q15834	CC85B_HUMAN	Coiled-coil domain-containing protein 85B	17873903	Coiled-coil domain containing 85B suppresses the beta-catenin activity in a p53-dependent manner.

P34932	HSP74_HUMAN	Heat shock 70 kDa protein 4	8335910	Molecular cloning of a novel human hsp70 from a B cell line and its assignment to chromosome 5.

O43677	NDUC1_HUMAN	NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial	9425316	Identification and primary structure of five human NADH-ubiquinone oxidoreductase subunits.

P86146	MASOD_ORADR	Eumenine mastoparan-OD	19857508	Isolation and molecular cloning of venom peptides from Orancistrocerus drewseni (Hymenoptera: Eumenidae).

Q63716	PRDX1_RAT	Peroxiredoxin-1	7577926	Purification, characterization, and cloning of a heme-binding protein (23 kDa) in rat liver cytosol.

P09798	CDC16_YEAST	Anaphase-promoting complex subunit CDC16	9660930	CDC16 controls initiation at chromosome replication origins.

O15467	CCL16_HUMAN	C-C motif chemokine 16	9642106	Isolation and characterization of LMC, a novel lymphocyte and monocyte chemoattractant human CC chemokine, with myelosuppressive activity.

C0LGT6	EFR_ARATH	LRR receptor-like serine/threonine-protein kinase EFR	16713565	Perception of the bacterial PAMP EF-Tu by the receptor EFR restricts Agrobacterium-mediated transformation.

Q9NPA1	KCMB3_HUMAN	Calcium-activated potassium channel subunit beta-3	10792058	A neuronal beta subunit (KCNMB4) makes the large conductance, voltage- and Ca2+-activated K+ channel resistant to charybdotoxin and iberiotoxin.

Q12396	EMP46_YEAST	Protein EMP46	16439369	Structures of the carbohydrate recognition domain of Ca2+-independent cargo receptors Emp46p and Emp47p.

Q08742	FMP31_YEAST	Putative thiosulfate sulfurtransferase FMP31, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

P20606	SAR1_YEAST	Small COPII coat GTPase SAR1	15665868	Dissection of COPII subunit-cargo assembly and disassembly kinetics during Sar1p-GTP hydrolysis.

P31266	SUH_MOUSE	Recombining binding protein suppressor of hairless	11318877	p48 subunit of mouse PTF1 binds to RBP-Jkappa/CBF-1, the intracellular mediator of Notch signalling, and is expressed in the neural tube of early stage embryos.

P39014	MET30_YEAST	F-box protein MET30	15870262	The F-box protein Met30 is required for multiple steps in the budding yeast cell cycle.

Q9Y6C5	PTC2_HUMAN	Protein patched homolog 2	9811851	Characterization of two patched receptors for the vertebrate hedgehog protein family.

O00400	ACATN_HUMAN	Acetyl-coenzyme A transporter 1	9096318	Expression cloning and characterization of a cDNA encoding a novel membrane protein required for the formation of O-acetylated gangliosides: a putative acetyl CoA transporter.

P38920	MLH1_YEAST	DNA mismatch repair protein MLH1	10570173	Functional specificity of MutL homologs in yeast: evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction.

P36115	IRS4_YEAST	Increased rDNA silencing protein 4	15265867	Negative regulation of phosphatidylinositol 4,5-bisphosphate levels by the INP51-associated proteins TAX4 and IRS4.

Q91Y94	COX42_RAT	Cytochrome c oxidase subunit 4 isoform 2, mitochondrial	11311561	Mammalian subunit IV isoforms of cytochrome c oxidase.

P97612	FAAH1_RAT	Fatty-acid amide hydrolase 1	9122178	Molecular characterization of human and mouse fatty acid amide hydrolases.

Q54QP6	OSB8_DICDI	Oxysterol-binding protein 8	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P16157	ANK1_HUMAN	Ankyrin-1	8640229	Ankyrin-1 mutations are a major cause of dominant and recessive hereditary spherocytosis.

O23617	TPS5_ARATH	Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 5	16771775	Phosphorylation and 14-3-3 binding of Arabidopsis trehalose-phosphate synthase 5 in response to 2-deoxyglucose.

Q96Q80	DERL3_HUMAN	Derlin-3	16449189	Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation.

Q54S20	MED13_DICDI	Mediator of RNA polymerase II transcription subunit 13	15259052	Keratocyte-like locomotion in amiB-null Dictyostelium cells.

Q7TN41	MRGRD_RAT	Mas-related G-protein coupled receptor member D	12909716	Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family.

P36630	CG22_SCHPO	G2/mitotic-specific cyclin cig2	11781565	Feedback regulation of the MBF transcription factor by cyclin Cig2.

Q9VCA2	ORCT_DROME	Organic cation transporter protein	9409773	The Orct gene of Drosophila melanogaster codes for a putative organic cation transporter with six or 12 transmembrane domains.

Q9H344	O51I2_HUMAN	Olfactory receptor 51I2	11121057	Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.

Q9USV6	CBP4_SCHPO	Assembly factor cbp4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Z2D7	MBD4_MOUSE	Methyl-CpG-binding domain protein 4	9774669	Identification and characterization of a family of mammalian methyl- CpG binding proteins.

P25847	MSH2_YEAST	DNA mismatch repair protein MSH2	8816473	The Saccharomyces cerevisiae Msh2 and Msh6 proteins form a complex that specifically binds to duplex oligonucleotides containing mismatched DNA base pairs.

O94511	YN67_SCHPO	Putative enoyl reductase C646.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q20334	TNNI1_CAEEL	Troponin I 1	14747334	Disruption of Caenorhabditis elegans muscle structure and function caused by mutation of troponin I.

P41411	CDC18_SCHPO	Cell division control protein 18	9203581	Fission yeast WD-repeat protein pop1 regulates genome ploidy through ubiquitin-proteasome-mediated degradation of the CDK inhibitor Rum1 and the S-phase initiator Cdc18.

Q12396	EMP46_YEAST	Protein EMP46	12134087	Emp47p and its close homolog Emp46p have a tyrosine-containing endoplasmic reticulum exit signal and function in glycoprotein secretion in Saccharomyces cerevisiae.

P30606	ITR2_YEAST	Myo-inositol transporter 2	16233524	Mutational analysis and localization of the inositol transporters of Saccharomyces cerevisiae.

P40427	EXD_DROME	Homeobox protein extradenticle	8104703	Extradenticle, a regulator of homeotic gene activity, is a homolog of the homeobox-containing human proto-oncogene pbx1.

Q91770	NOT2_XENLA	Homeobox protein not2	11585804	Role of Goosecoid, Xnot and Wnt antagonists in the maintenance of the notochord genetic programme in Xenopus gastrulae.

Q15326	ZMY11_HUMAN	Zinc finger MYND domain-containing protein 11	7621829	BS69, a novel adenovirus E1A-associated protein that inhibits E1A transactivation.

O94236	EIF3D_SCHPO	Eukaryotic translation initiation factor 3 subunit D	9892665	Moe1, a conserved protein in Schizosaccharomyces pombe, interacts with a Ras effector, Scd1, to affect proper spindle formation.

P51617	IRAK1_HUMAN	Interleukin-1 receptor-associated kinase 1	12874243	Pellino3, a novel member of the Pellino protein family, promotes activation of c-Jun and Elk-1 and may act as a scaffolding protein.

P32797	CDC13_YEAST	Cell division control protein 13	11390652	New function of CDC13 in positive telomere length regulation.

P55769	NH2L1_HUMAN	NHP2-like protein 1	10593953	HRad17 colocalizes with NHP2L1 in the nucleolus and redistributes after UV irradiation.

P10092	CALCB_HUMAN	Calcitonin gene-related peptide 2	2985435	A second human calcitonin/CGRP gene.

Q9EPM5	SYNCI_MOUSE	Syncoilin	11694502	Association of syncoilin and desmin: linking intermediate filament proteins to the dystrophin-associated protein complex.

Q11085	CLC2_CAEEL	Clc-like protein 2	10395899	Identification and characterization of a new member of the gas3/PMP22 gene family in C. elegans.

Q70PP2	SMG1_DROME	Serine/threonine-protein kinase Smg1	12881430	Nonsense-mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathways.

Q9NVX0	HAUS2_HUMAN	HAUS augmin-like complex subunit 2	14654843	Proteomic characterization of the human centrosome by protein correlation profiling.

P87167	BUT2_SCHPO	Uba3-binding protein but2	14623327	But1 and But2 proteins bind to Uba3, a catalytic subunit of E1 for neddylation, in fission yeast.

O13824	NMD2_SCHPO	Nonsense-mediated mRNA decay protein 2	11073994	Novel Upf2p orthologues suggest a functional link between translation initiation and nonsense surveillance complexes.

Q8BJQ4	TCAM2_MOUSE	TIR domain-containing adapter molecule 2	14556004	TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway.

P38804	SDO1L_YEAST	SDO1-like protein YHR087W	15701634	The Shwachman-Bodian-Diamond syndrome protein family is involved in RNA metabolism.

Q07418	PEX19_YEAST	Peroxisomal membrane protein import receptor PEX19	16009135	Contribution of the endoplasmic reticulum to peroxisome formation.

P0ABF1	PCNB_ECOLI	Poly(A) polymerase	2537812	Genetics and sequence analysis of the pcnB locus, an Escherichia coli gene involved in plasmid copy number control.

Q9Y5S9	RBM8A_HUMAN	RNA-binding protein 8A	11030346	Pre-mRNA splicing imprints mRNA in the nucleus with a novel RNA- binding protein that persists in the cytoplasm.

P33568	RB_RAT	Retinoblastoma-associated protein	19081374	A calcium-dependent switch in a CREST-BRG1 complex regulates activity-dependent gene expression.

Q9VSL7	FOI_DROME	Zinc transporter foi	12702650	fear of intimacy encodes a novel transmembrane protein required for gonad morphogenesis in Drosophila.

O14142	SYM1_SCHPO	Protein sym1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9VZZ9	DOS_DROME	Protein daughter of sevenless	10640704	In vivo functional analysis of the daughter of sevenless protein in receptor tyrosine kinase signaling.

P31016	DLG4_RAT	Disks large homolog 4	7569905	Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95.

Q01881	RA05_ORYSJ	Seed allergenic protein RA5	7678765	Gene structure and expression of rice seed allergenic proteins belonging to the alpha-amylase/trypsin inhibitor family.

Q9LXS1	MTPA2_ARATH	Metal tolerance protein A2	15215502	Isolation of intact vacuoles and proteomic analysis of tonoplast from suspension-cultured cells of Arabidopsis thaliana.

Q07458	RXT3_YEAST	Transcriptional regulatory protein RXT3	16314178	Stable incorporation of sequence specific repressors Ash1 and Ume6 into the Rpd3L complex.

Q96AH0	SOSB2_HUMAN	SOSS complex subunit B2	19605351	hSSB1 and hSSB2 form similar multiprotein complexes that participate in DNA damage response.

Q08176	MIM1_YEAST	Mitochondrial import protein 1	15326197	Two novel proteins in the mitochondrial outer membrane mediate beta- barrel protein assembly.

O80623	Y2393_ARATH	Probable receptor-like protein kinase At2g39360	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q8I4V2	RBM22_PLAF7	Pre-mRNA-splicing factor PFL2310w	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

O43739	CYH3_HUMAN	Cytohesin-3	9742223	Nerve growth factor- and epidermal growth factor-stimulated translocation of the ADP-ribosylation factor-exchange factor GRP1 to the plasma membrane of PC12 cells requires activation of phosphatidylinositol 3-kinase and the GRP1 pleckstrin homology domain.

O74861	SDC1_SCHPO	Set1 complex component sdc1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P31997	CEAM8_HUMAN	Carcinoembryonic antigen-related cell adhesion molecule 8	2208113	Cloning of a carcinoembryonic antigen gene family member expressed in leukocytes of chronic myeloid leukemia patients and bone marrow.

P40031	SPO73_YEAST	Sporulation-specific protein 73	15590821	Morphogenetic pathway of spore wall assembly in Saccharomyces cerevisiae.

Q8I7Q0	GAGO_DROME	Retrovirus-related Gag polyprotein from transposon opus	12537573	The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

Q12255	NYV1_YEAST	Vacuolar v-SNARE NYV1	16855025	Identification of the yeast R-SNARE Nyv1p as a novel longin domain- containing protein.

Q06833	YP091_YEAST	Uncharacterized PH domain-containing protein YPR091C	14562095	Global analysis of protein localization in budding yeast.

O59868	ATC1_SCHPO	Calcium-transporting ATPase 1	15470240	Schizosaccharomyces pombe Pmr1p is essential for cell wall integrity and is required for polarized cell growth and cytokinesis.

P20702	ITAX_HUMAN	Integrin alpha-X	3327687	cDNA cloning and complete primary structure of the alpha subunit of a leukocyte adhesion glycoprotein, p150,95.

P34299	GLR1_CAEEL	Glutamate receptor 1	7477293	Mechanosensory signalling in C. elegans mediated by the GLR-1 glutamate receptor.

O59757	SPC7_SCHPO	Kinetochore protein spc7	17035632	Reconstruction of the kinetochore during meiosis in fission yeast Schizosaccharomyces pombe.

Q9UL58	ZN215_HUMAN	Zinc finger protein 215	10762538	Disruption of a novel imprinted zinc-finger gene, ZNF215, in Beckwith-Wiedemann syndrome.

P28704	RXRB_MOUSE	Retinoic acid receptor RXR-beta	1312497	Characterization of three RXR genes that mediate the action of 9-cis retinoic acid.

O44664	NLP29_CAEEL	Neuropeptide-like protein 29	15048112	TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM.

Q09717	RANG_SCHPO	Ran-specific GTPase-activating protein 1	9504913	The identification of cDNAs that affect the mitosis-to-interphase transition in Schizosaccharomyces pombe, including sbp1, which encodes a spi1p-GTP-binding protein.

Q18967	EIF3F_CAEEL	Eukaryotic translation initiation factor 3 subunit F	17411345	Lifespan regulation by evolutionarily conserved genes essential for viability.

Q9SZR1	ACA10_ARATH	Calcium-transporting ATPase 10, plasma membrane-type	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q91ZD4	VANG2_MOUSE	Vang-like protein 2	16687519	Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals.

P97865	PEX7_MOUSE	Peroxisomal targeting signal 2 receptor	9090381	Human PEX7 encodes the peroxisomal PTS2 receptor and is responsible for rhizomelic chondrodysplasia punctata.

Q94A76	GORK_ARATH	Potassium channel GORK	12671068	The Arabidopsis outward K(+) channel GORK is involved in regulation of stomatal movements and plant transpiration.

Q9PT67	FXD5C_XENLA	Forkhead box protein D5-C	15656969	Of fox and frogs: fox (fork head/winged helix) transcription factors in Xenopus development.

Q9UKW6	ELF5_HUMAN	ETS-related transcription factor Elf-5	9840936	A novel transcription factor, ELF5, belongs to the ELF subfamily of ETS genes and maps to human chromosome 11p13-15, a region subject to LOH and rearrangement in human carcinoma cell lines.

O15534	PER1_HUMAN	Period circadian protein homolog 1	9333243	Circadian oscillation of a mammalian homologue of the Drosophila period gene.

P63281	UBC9_RAT	SUMO-conjugating enzyme UBC9	9013644	Degradation of E2A proteins through a ubiquitin-conjugating enzyme, UbcE2A.

Q7L523	RRAGA_HUMAN	Ras-related GTP-binding protein A	7499430	Cloning of a novel family of mammalian GTP-binding proteins (RagA, RagBs, RagBl) with remote similarity to the Ras-related GTPases.

Q9BXN2	CLC7A_HUMAN	C-type lectin domain family 7 member A	11567029	Characterization of the human beta-glucan receptor and its alternatively spliced isoforms.

P47792	SX19A_DANRE	Transcription factor Sox-19a	16408288	Comparative genomic and expression analysis of group B1 sox genes in zebrafish indicates their diversification during vertebrate evolution.

Q9Y5L4	TIM13_HUMAN	Mitochondrial import inner membrane translocase subunit Tim13	10552927	The human family of deafness/dystonia peptide (DDP) related mitochondrial import proteins.

Q9W1V1	ANM7_DROME	Protein arginine N-methyltransferase 7	18369183	Sm protein methylation is dispensable for snRNP assembly in Drosophila melanogaster.

Q8K4J6	MKL1_MOUSE	MKL/myocardin-like protein 1	19350017	SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta1-integrin.

P12688	YPK1_YEAST	Serine/threonine-protein kinase YPK1	12221112	Pkh1 and pkh2 differentially phosphorylate and activate ypk1 and ykr2 and define protein kinase modules required for maintenance of cell wall integrity.

Q9V9S8	HEMH_DROME	Ferrochelatase, mitochondrial	9712849	Evidence that the fourth ligand to the 2Fe-2S cluster in animal ferrochelatase is a cysteine. Characterization of the enzyme from Drosophila melanogaster.

Q96LB1	MRGX2_HUMAN	Mas-related G-protein coupled receptor member X2	12915402	MrgX2 is a high potency cortistatin receptor expressed in dorsal root ganglion.

P41546	HAC1_YEAST	Transcriptional activator HAC1	9077435	Signalling from endoplasmic reticulum to nucleus: transcription factor with a basic-leucine zipper motif is required for the unfolded protein-response pathway.

P55215	CASP2_RAT	Caspase-2	9427555	Cloning and expression of the cDNA encoding rat caspase-2.

P06844	SPT3_YEAST	Protein SPT3	9674426	A subset of TAF(II)s are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulation.

P33760	PEX6_YEAST	Peroxisomal ATPase PEX6	15634331	Structural and functional analysis of the interaction of the AAA- peroxins Pex1p and Pex6p.

P41903	PTE1_YEAST	Peroxisomal acyl-coenzyme A thioester hydrolase 1	10092594	Identification of peroxisomal acyl-CoA thioesterases in yeast and humans.

Q12166	LEU9_YEAST	2-isopropylmalate synthase 2, mitochondrial	10790691	Identification by functional analysis of the gene encoding alpha- isopropylmalate synthase II (LEU9) in Saccharomyces cerevisiae.

Q9ESJ1	CABL1_MOUSE	CDK5 and ABL1 enzyme substrate 1	11706030	Differential effect of ik3-1/cables on p53- and p73-induced cell death.

P42785	PCP_HUMAN	Lysosomal Pro-X carboxypeptidase	28321	Purification and properties of prolylcarboxypeptidase (angiotensinase C) from human kidney.

Q6PFD5	DLGP3_MOUSE	Disks large-associated protein 3	15024750	Differential mRNA expression and protein localization of the SAP90/PSD-95-associated proteins (SAPAPs) in the nervous system of the mouse.

P38123	SWD3_YEAST	COMPASS component SWD3	11687631	COMPASS: a complex of proteins associated with a trithorax-related SET domain protein.

P27929	NAM9_YEAST	37S ribosomal protein NAM9, mitochondrial	11278769	Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues.

P30046	DOPD_HUMAN	D-dopachrome decarboxylase	9480844	Molecular cloning of human D-dopachrome tautomerase cDNA: N-terminal proline is essential for enzyme activation.

Q9SCR2	KRP2_ARATH	Cyclin-dependent kinase inhibitor 2	10758489	The Arabidopsis Cdc2a-interacting protein ICK2 is structurally related to ICK1 and is a potent inhibitor of cyclin-dependent kinase activity in vitro.

P38698	PPX1_YEAST	Exopolyphosphatase	7860598	The gene for a major exopolyphosphatase of Saccharomyces cerevisiae.

Q6P0Q8	MAST2_HUMAN	Microtubule-associated serine/threonine-protein kinase 2	12117771	Protocadherin LKC, a new candidate for a tumor suppressor of colon and liver cancers, its association with contact inhibition of cell proliferation.

Q9Y276	BCS1_HUMAN	Mitochondrial chaperone BCS1	9878253	Identification and characterization of human cDNAs specific to BCS1, PET112, SCO1, COX15, and COX11, five genes involved in the formation and function of the mitochondrial respiratory chain.

P47818	CCC1_YEAST	Protein CCC1	11390404	CCC1 is a transporter that mediates vacuolar iron storage in yeast.

P51593	HUWE1_RAT	E3 ubiquitin-protein ligase HUWE1	7968380	Cloning of a DNA binding protein that is a tyrosine kinase substrate and recognizes an upstream initiator-like sequence in the promoter of the preprodynorphin gene.

Q9FN02	PPP7_ARATH	Serine/threonine-protein phosphatase 7	11703093	Nuclear localization of the plant protein Ser/Thr phosphatase PP7.

Q04925	YDR22_YEAST	SVF1-like protein YDR222W	14562095	Global analysis of protein localization in budding yeast.

P13483	DATI_YEAST	Oligo(A)/oligo(T)-binding protein	2670564	A DNA binding protein that recognizes oligo(dA).oligo(dT) tracts.

Q8S9F1	PCYAB_EUGGR	Photoactivated adenylate cyclase subunit beta	11875575	A blue-light-activated adenylyl cyclase mediates photoavoidance in Euglena gracilis.

Q8NEV4	MYO3A_HUMAN	Myosin-IIIa	12032315	From flies' eyes to our ears: mutations in a human class III myosin cause progressive nonsyndromic hearing loss DFNB30.

Q8K3I9	GLCI1_MOUSE	Glucocorticoid-induced transcript 1 protein	12557054	Two genes, three messengers: hybrid transcript between a gene expressed at specific stages of T-cell and sperm maturation and an unrelated adjacent gene.

P51610	HCFC1_HUMAN	Host cell factor 1	19377461	GlcNAcylation of a histone methyltransferase in retinoic-acid-induced granulopoiesis.

Q9HDX7	YK1D_SCHPO	Uncharacterized protein PB1A10.13	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O73693	EGR1_TAEGU	Early growth response protein 1	9501495	Evolutionary conservation of the immediate-early gene ZENK.

Q949Y0	UBP6_ARATH	Ubiquitin carboxyl-terminal hydrolase 6	15987637	Arabidopsis ubiquitin-specific protease 6 (AtUBP6) interacts with calmodulin.

P23293	BUR1_YEAST	Serine/threonine-protein kinase BUR1	11390638	Phosphorylation of the RNA polymerase II carboxy-terminal domain by the Bur1 cyclin-dependent kinase.

P21796	VDAC1_HUMAN	Voltage-dependent anion-selective channel protein 1	8420959	Cloning and functional expression in yeast of two human isoforms of the outer mitochondrial membrane channel, the voltage-dependent anion channel.

Q08602	PGTA_RAT	Geranylgeranyl transferase type-2 subunit alpha	8505342	cDNA cloning and expression of the alpha and beta subunits of rat Rab geranylgeranyl transferase.

P29288	PPA5_RAT	Tartrate-resistant acid phosphatase type 5	1722212	Cloning, sequence, and developmental expression of a type 5, tartrate-resistant, acid phosphatase of rat bone.

Q08176	MIM1_YEAST	Mitochondrial import protein 1	15242642	Exploration of essential gene functions via titratable promoter alleles.

Q6P0E1	SOX2_DANRE	Transcription factor Sox-2	16408288	Comparative genomic and expression analysis of group B1 sox genes in zebrafish indicates their diversification during vertebrate evolution.

O74874	CCR4_SCHPO	Glucose-repressible alcohol dehydrogenase transcriptional effector	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q55DB0	SIR2E_DICDI	NAD-dependent deacetylase sir2E	18707607	Analysis of Sir2E in the cellular slime mold Dictyostelium discoideum: cellular localization, spatial expression and overexpression.

P61073	CXCR4_HUMAN	C-X-C chemokine receptor type 4	20228059	CXC chemokine receptor 4 is a cell surface receptor for extracellular ubiquitin.

P08962	CD63_HUMAN	CD63 antigen	1993697	CD63 antigen. A novel lysosomal membrane glycoprotein, cloned by a screening procedure for intracellular antigens in eukaryotic cells.

O14341	RM35_SCHPO	60S ribosomal protein L35, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q6SCL4	APYA_EMENI	HECT-type ubiquitin ligase-interacting protein apyA	15255903	A role for creD, a carbon catabolite repression gene from Aspergillus nidulans, in ubiquitination.

Q8MSV2	SHEP_DROME	Protein alan shepard	16594976	Gravitaxis in Drosophila melanogaster: a forward genetic screen.

P53722	ATP23_YEAST	Mitochondrial inner membrane protease ATP23	17135290	The metalloprotease encoded by ATP23 has a dual function in processing and assembly of subunit 6 of mitochondrial ATPase.

Q9Y6D6	BIG1_HUMAN	Brefeldin A-inhibited guanine nucleotide-exchange protein 1	19651892	A role of histone H3 lysine 4 methyltransferase components in endosomal trafficking.

Q9WVC7	AKAP6_RAT	A-kinase anchor protein 6	10413680	mAKAP: an A-kinase anchoring protein targeted to the nuclear membrane of differentiated myocytes.

Q9Y2H1	ST38L_HUMAN	Serine/threonine-protein kinase 38-like	15067004	Human Mob proteins regulate the NDR1 and NDR2 serine-threonine kinases.

Q8S8I2	ULT2_ARATH	Protein ULTRAPETALA 2	15673576	ULTRAPETALA1 encodes a SAND domain putative transcriptional regulator that controls shoot and floral meristem activity in Arabidopsis.

P29016	CD1B_HUMAN	T-cell surface glycoprotein CD1b	2447586	Structure and expression of the human thymocyte antigens CD1a, CD1b, and CD1c.

P31325	PHKG2_RAT	Phosphorylase b kinase gamma catalytic chain, testis/liver isoform	1370475	Molecular cloning and enzymatic analysis of the rat homolog of 'PhK- gamma T,' an isoform of phosphorylase kinase catalytic subunit.

P40581	GPX3_YEAST	Peroxiredoxin HYR1	12437921	A thiol peroxidase is an H2O2 receptor and redox-transducer in gene activation.

P80385	AAKG1_RAT	5'-AMP-activated protein kinase subunit gamma-1	8626596	Characterization of AMP-activated protein kinase beta and gamma subunits. Assembly of the heterotrimeric complex in vitro.

Q15642	CIP4_HUMAN	Cdc42-interacting protein 4	9210375	A Cdc42 target protein with homology to the non-kinase domain of FER has a potential role in regulating the actin cytoskeleton.

O75293	GA45B_HUMAN	Growth arrest and DNA damage-inducible protein GADD45 beta	9827804	A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK.

Q62009	POSTN_MOUSE	Periostin	10404027	Identification and characterization of a novel protein, periostin, with restricted expression to periosteum and periodontal ligament and increased expression by transforming growth factor beta.

P38352	SAF1_YEAST	SCF-associated factor 1	16677311	Proteasome- and SCF-dependent degradation of yeast adenine deaminase upon transition from proliferation to quiescence requires a new F-box protein named Saf1p.

O74561	YCZ8_SCHPO	Uncharacterized inositol polyphosphate kinase C970.08	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O88626	GALR3_RAT	Galanin receptor type 3	9722565	Cloned human and rat galanin GALR3 receptors: pharmacology and activation of G-protein inwardly rectifying K+ channels.

Q9NU63	ZFP57_HUMAN	Zinc finger protein 57 homolog	18622393	Hypomethylation of multiple imprinted loci in individuals with transient neonatal diabetes is associated with mutations in ZFP57.

P07550	ADRB2_HUMAN	Beta-2 adrenergic receptor	2823249	Structure of the gene for human beta 2-adrenergic receptor: expression and promoter characterization.

Q9NP78	ABCB9_HUMAN	ATP-binding cassette sub-family B member 9	10748049	Characterization of ABCB9, an ATP binding cassette protein associated with lysosomes.

Q6ZRS2	SRCAP_HUMAN	Helicase SRCAP	10347196	Identification of a novel SNF2/SWI2 protein family member, SRCAP, which interacts with CREB-binding protein.

P21802	FGFR2_HUMAN	Fibroblast growth factor receptor 2	1400433	A novel form of fibroblast growth factor receptor 2. Alternative splicing of the third immunoglobulin-like domain confers ligand binding specificity.

Q9UT81	UBX3_SCHPO	UBX domain-containing protein 3	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

P53652	SODM_PSEAE	Superoxide dismutase [Mn]	8244935	Cloning and characterization of the Pseudomonas aeruginosa sodA and sodB genes encoding manganese- and iron-cofactored superoxide dismutase: demonstration of increased manganese superoxide dismutase activity in alginate-producing bacteria.

Q8I3Y6	PFD6_PLAF7	Probable prefoldin subunit 6	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

P07548	DFD_DROME	Homeotic protein deformed	12202035	The Drosophila Hox gene deformed sculpts head morphology via direct regulation of the apoptosis activator reaper.

Q9SKK4	GSL_ARATH	Probable 2-oxoacid dependent dioxygenase	18945935	A novel 2-oxoacid-dependent dioxygenase involved in the formation of the goiterogenic 2-hydroxybut-3-enyl glucosinolate and generalist insect resistance in Arabidopsis.

P04823	IL3_RAT	Interleukin-3	3086845	Cloning and expression of the rat interleukin-3 gene.

P38811	TRA1_YEAST	Transcription-associated protein 1	9756893	Tra1p is a component of the yeast Ada.Spt transcriptional regulatory complexes.

Q967F4	HMR1_CAEEL	Cadherin-related hmr-1	11790304	The C. elegans hmr-1 gene can encode a neuronal classic cadherin involved in the regulation of axon fasciculation.

Q99220	OS9_YEAST	Protein OS-9 homolog	16168370	Exploration of the topological requirements of ERAD identifies Yos9p as a lectin sensor of misfolded glycoproteins in the ER lumen.

Q12334	SCM3_YEAST	Protein SCM3	14562095	Global analysis of protein localization in budding yeast.

Q9V496	APLP_DROME	Apolipophorins	8031123	A glycoprotein binding retinoids and fatty acids is present in Drosophila.

Q9HBY8	SGK2_HUMAN	Serine/threonine-protein kinase Sgk2	12397388	K(+) channel activation by all three isoforms of serum- and glucocorticoid-dependent protein kinase SGK.

Q8VY86	MSRB7_ARATH	Peptide methionine sulfoxide reductase B7	17031545	Plant methionine sulfoxide reductase A and B multigenic families.

O97935	MSPE_SAGOE	Beta-microseminoprotein E1	10491085	New world, but not old world, monkeys carry several genes encoding beta-microseminoprotein.

Q5BAS1	XYND_EMENI	Exo-1,4-beta-xylosidase xlnD	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

O60016	CLR4_SCHPO	Histone-lysine N-methyltransferase, H3 lysine-9 specific	16127433	Ubiquitin ligase component Cul4 associates with Clr4 histone methyltransferase to assemble heterochromatin.

Q8S8E3	PYL6_ARATH	Abscisic acid receptor PYL6	19624469	Modulation of drought resistance by the abscisic acid receptor PYL5 through inhibition of clade A PP2Cs.

Q08345	DDR1_HUMAN	Epithelial discoidin domain-containing receptor 1	8390675	A receptor tyrosine kinase found in breast carcinoma cells has an extracellular discoidin I-like domain.

P03406	NEF_HV1BR	Protein Nef	8681387	Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain.

P46781	RS9_HUMAN	40S ribosomal protein S9	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

O14656	TOR1A_HUMAN	Torsin-1A	9288096	The early-onset torsion dystonia gene (DYT1) encodes an ATP-binding protein.

P14091	CATE_HUMAN	Cathepsin E	8765029	Regulation of cathepsin E expression during human B cell differentiation in vitro.

Q9UIK4	DAPK2_HUMAN	Death-associated protein kinase 2	10376525	Death-associated protein kinase 2 is a new calcium/calmodulin- dependent protein kinase that signals apoptosis through its catalytic activity.

P34093	NDKM_DICDI	Nucleoside diphosphate kinase, mitochondrial	8244981	Separate nuclear genes encode cytosolic and mitochondrial nucleoside diphosphate kinase in Dictyostelium discoideum.

O13310	ORB6_SCHPO	Serine/threonine-protein kinase orb6	9636183	Fission yeast orb6, a ser/thr protein kinase related to mammalian rho kinase and myotonic dystrophy kinase, is required for maintenance of cell polarity and coordinates cell morphogenesis with the cell cycle.

Q03957	CTK1_YEAST	CTD kinase subunit alpha	12504017	The RNA polymerase II CTD kinase CTDK-I affects pre-mRNA 3' cleavage/polyadenylation through the processing component Pti1p.

O75604	UBP2_HUMAN	Ubiquitin carboxyl-terminal hydrolase 2	19838211	MdmX is a substrate for the deubiquitinating enzyme USP2a.

Q26304	LUCI_LUCMI	Luciferin 4-monooxygenase	2801227	Luciferase of Luciola mingrelica fireflies. Kinetics and regulation mechanism.

P81900	KAPR2_DROME	cAMP-dependent protein kinase type II regulatory subunit	9196067	Purification of a regulatory subunit of type II cAMP-dependent protein kinase from Drosophila heads.

Q6NYC1	JMJD6_HUMAN	Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6	19574390	Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing.

Q9HBW0	LPAR2_HUMAN	Lysophosphatidic acid receptor 2	19306925	Dual regulation of lysophosphatidic acid (LPA1) receptor signalling by Ral and GRK.

Q969F2	NKD2_HUMAN	Protein naked cuticle homolog 2	15064403	Myristoylated Naked2 escorts transforming growth factor alpha to the basolateral plasma membrane of polarized epithelial cells.

Q9H410	DSN1_HUMAN	Kinetochore-associated protein DSN1 homolog	15502821	A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1.

O64903	NDK2_ARATH	Nucleoside diphosphate kinase II, chloroplastic	12506203	NDP kinase 2 interacts with two oxidative stress-activated MAPKs to regulate cellular redox state and enhances multiple stress tolerance in transgenic plants.

O43809	CPSF5_HUMAN	Cleavage and polyadenylation specificity factor subunit 5	8626397	Purification and characterization of human cleavage factor Im involved in the 3' end processing of messenger RNA precursors.

P36139	PET10_YEAST	Protein PET10	10515935	Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiae.

P47039	BNA3_YEAST	Probable kynurenine--oxoglutarate transaminase BNA3	14562095	Global analysis of protein localization in budding yeast.

O96007	MOC2B_HUMAN	Molybdopterin synthase catalytic subunit	15073332	Evidence for the physiological role of a rhodanese-like protein for the biosynthesis of the molybdenum cofactor in humans.

Q63250	FOXE3_RAT	Forkhead box protein E3	7683413	Identification of nine tissue-specific transcription factors of the hepatocyte nuclear factor 3/forkhead DNA-binding-domain family.

Q9UUA2	PIF1_SCHPO	DNA repair and recombination protein pif1, mitochondrial	12058079	Schizosaccharomyces pombe pfh1(+) encodes an essential 5' to 3' DNA helicase that is a member of the PIF1 subfamily of DNA helicases.

Q8WY64	MYLIP_HUMAN	E3 ubiquitin-protein ligase MYLIP	12826659	MSAP is a novel MIR-interacting protein that enhances neurite outgrowth and increases myosin regulatory light chain.

Q92793	CBP_HUMAN	CREB-binding protein	17525332	ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

Q62876	SNG1_RAT	Synaptogyrin-1	8557746	Structure of synaptogyrin (p29) defines novel synaptic vesicle protein.

Q8S8Y8	WNK6_ARATH	Probable serine/threonine-protein kinase WNK6	12506983	Compilation and characterization of a novel WNK family of protein kinases in Arabiodpsis thaliana with reference to circadian rhythms.

P00635	PPA5_YEAST	Repressible acid phosphatase	16278456	Pho5p and newly identified nucleotide pyrophosphatases/ phosphodiesterases regulate extracellular nucleotide phosphate metabolism in Saccharomyces cerevisiae.

O74972	FYV4_SCHPO	Protein fyv4, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P54819	KAD2_HUMAN	Adenylate kinase 2, mitochondrial	9504408	Cloning and expression of human adenylate kinase 2 isozymes: differential expression of adenylate kinase 1 and 2 in human muscle tissues.

Q9Y4K3	TRAF6_HUMAN	TNF receptor-associated factor 6	17449468	RBCK1 negatively regulates tumor necrosis factor- and interleukin-1- triggered NF-kappaB activation by targeting TAB2/3 for degradation.

Q96QU1	PCD15_HUMAN	Protocadherin-15	11487575	Mutations in the novel protocadherin PCDH15 cause Usher syndrome type 1F.

Q8CD91	SMOC2_MOUSE	SPARC-related modular calcium-binding protein 2	18757743	Transcriptome-based systematic identification of extracellular matrix proteins.

O13795	POF8_SCHPO	Protein pof8	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Z2V6	HDAC5_MOUSE	Histone deacetylase 5	15140878	Transcriptional regulation by the repressor of estrogen receptor activity via recruitment of histone deacetylases.

P38248	ECM33_YEAST	Cell wall protein ECM33	12583915	The localization change of Ybr078w/Ecm33, a yeast GPI-associated protein, from the plasma membrane to the cell wall, affecting the cellular function.

A7TZE6	SKIT1_MOUSE	Selection and upkeep of intraepithelial T-cells protein 1	18408721	Skint1, the prototype of a newly identified immunoglobulin superfamily gene cluster, positively selects epidermal gammadelta T cells.

P0AEF4	DPIA_ECOLI	Transcriptional regulatory protein DpiA	18997424	Anaerobic regulation of citrate fermentation by CitAB in Escherichia coli.

P23258	TBG1_HUMAN	Tubulin gamma-1 chain	9566969	Characterization of the human homologue of the yeast spc98p and its association with gamma-tubulin.

Q9XJ66	MAD22_ORYSJ	MADS-box transcription factor 22	15682279	OsMADS22, an STMADS11-like MADS-box gene of rice, is expressed in non-vegetative tissues and its ectopic expression induces spikelet meristem indeterminacy.

P36592	RAD22_SCHPO	DNA repair and recombination protein rad22	8290356	The fission yeast rad22 gene, having a function in mating-type switching and repair of DNA damages, encodes a protein homolog to Rad52 of Saccharomyces cerevisiae.

P15056	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	2284096	Complete coding sequence of a human B-raf cDNA and detection of B-raf protein kinase with isozyme specific antibodies.

Q9JIL3	ILF3_RAT	Interleukin enhancer-binding factor 3	10749851	Protein-arginine methyltransferase I, the predominant protein- arginine methyltransferase in cells, interacts with and is regulated by interleukin enhancer-binding factor 3.

O01427	AIR2_CAEEL	Aurora/IPL1-related protein kinase 2	15548597	The Caenorhabditis elegans Aurora B kinase AIR-2 phosphorylates and is required for the localization of a BimC kinesin to meiotic and mitotic spindles.

P54199	MPS1_YEAST	Serine/threonine-protein kinase MPS1	7737118	Yeast spindle pole body duplication gene MPS1 encodes an essential dual specificity protein kinase.

Q19192	E2AK3_CAEEL	Eukaryotic translation initiation factor 2-alpha kinase	11779465	Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development.

Q9Y820	YON7_SCHPO	PCI domain-containing protein C1105.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8WYQ5	DGCR8_HUMAN	Microprocessor complex subunit DGCR8	15574589	The Drosha-DGCR8 complex in primary microRNA processing.

Q9ZV65	HDG3_ARATH	Homeobox-leucine zipper protein HDG3	16778018	Characterization of the class IV homeodomain-leucine zipper gene family in Arabidopsis.

P15291	B4GT1_HUMAN	Beta-1,4-galactosyltransferase 1	2120039	Analysis of the substrate binding sites of human galactosyltransferase by protein engineering.

O82302	P2C29_ARATH	Protein phosphatase 2C 29	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

P48167	GLRB_HUMAN	Glycine receptor subunit beta	8717357	The human glycine receptor beta subunit: primary structure, functional characterisation and chromosomal localisation of the human and murine genes.

Q9I958	MK14B_CYPCA	Mitogen-activated protein kinase 14B	10880959	Identification of a nuclear export signal in MKK6, an activator of the carp p38 mitogen-activated protein kinases.

O75317	UBP12_HUMAN	Ubiquitin carboxyl-terminal hydrolase 12	19075014	UAF1 is a subunit of multiple deubiquitinating enzyme complexes.

Q9UIM3	FKBPL_HUMAN	FK506-binding protein-like	10521921	A novel human stress response-related gene with a potential role in induced radioresistance.

P15265	MCSP_MOUSE	Sperm mitochondrial-associated cysteine-rich protein	11940662	Asthenozoospermia in mice with targeted deletion of the sperm mitochondrion-associated cysteine-rich protein (Smcp) gene.

Q9GYI4	JMJD6_CAEEL	Bifunctional arginine demethylase and lysyl-hydroxylase psr-1	14645848	Cell corpse engulfment mediated by C. elegans phosphatidylserine receptor through CED-5 and CED-12.

Q9H1K0	RBNS5_HUMAN	Rabenosyn-5	16034420	Structural basis of family-wide Rab GTPase recognition by rabenosyn- 5.

P43251	BTD_HUMAN	Biotinidase	7509806	Human serum biotinidase. cDNA cloning, sequence, and characterization.

Q91YR1	TWF1_MOUSE	Twinfilin-1	10669753	Mouse A6/twinfilin is an actin monomer-binding protein that localizes to the regions of rapid actin dynamics.

Q00169	PIPNA_HUMAN	Phosphatidylinositol transfer protein alpha isoform	8194769	Sequence of a human cDNA encoding phosphatidylinositol transfer protein and occurrence of a related sequence in widely divergent eukaryotes.

Q9UBE0	SAE1_HUMAN	SUMO-activating enzyme subunit 1	20164921	Active site remodelling accompanies thioester bond formation in the SUMO E1.

Q8STE5	CED12_CAEEL	Cell death abnormality protein 12	14645848	Cell corpse engulfment mediated by C. elegans phosphatidylserine receptor through CED-5 and CED-12.

O13959	RBX1_SCHPO	RING-box protein pip1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8R0W6	NFIP1_MOUSE	NEDD4 family-interacting protein 1	11748237	N4WBP5, a potential target for ubiquitination by the Nedd4 family of proteins, is a novel Golgi-associated protein.

Q9Y224	CN166_HUMAN	UPF0568 protein C14orf166	15147888	A novel ninein-interaction protein, CGI-99, blocks ninein phosphorylation by GSK3beta and is highly expressed in brain tumors.

P27881	HXK2_RAT	Hexokinase-2	7622509	Glucose catabolism in cancer cells. Isolation, sequence, and activity of the promoter for type II hexokinase.

O60519	CRBL2_HUMAN	cAMP-responsive element-binding protein-like 2	9693048	CREBL2, a novel transcript from the chromosome 12 region flanked by ETV6 and CDKN1B.

P42679	MATK_HUMAN	Megakaryocyte-associated tyrosine-protein kinase	8288563	Identification and characterization of a novel tyrosine kinase from megakaryocytes.

P11055	MYH3_HUMAN	Myosin-3	1691980	Identification of three developmentally controlled isoforms of human myosin heavy chains.

P22888	LSHR_HUMAN	Lutropin-choriogonadotropic hormone receptor	7719343	Male pseudohermaphroditism due to a homozygous missense mutation of the luteinizing hormone receptor gene.

O35980	NTHL1_MOUSE	Endonuclease III-like protein 1	12531031	Differential intracellular localization of the human and mouse endonuclease III homologs and analysis of the sorting signals.

Q9R109	OAZ3_MOUSE	Ornithine decarboxylase antizyme 3	10781085	Discovery of a spermatogenesis stage-specific ornithine decarboxylase antizyme: antizyme 3.

P12830	CADH1_HUMAN	Cadherin-1	11076937	Cleavage and shedding of E-cadherin after induction of apoptosis.

O24646	HY5_ARATH	Transcription factor HY5	10990463	HY5 stability and activity in Arabidopsis is regulated by phosphorylation in its COP1 binding domain.

Q80XH2	IMPG2_MOUSE	Interphotoreceptor matrix proteoglycan 2	15044457	Spacrcan binding to hyaluronan and other glycosaminoglycans. Molecular and biochemical studies.

P25719	CYPC_YEAST	Peptidyl-prolyl cis-trans isomerase C, mitochondrial	7603990	Cyclophilin catalyzes protein folding in yeast mitochondria.

P07713	DECA_DROME	Protein decapentaplegic	12135920	Dpp signalling is a key effector of the wing-body wall subdivision of the Drosophila mesothorax.

P46148	ETRA_SHEON	Electron transport regulator A	8253682	Sequence and genetic characterization of etrA, an fnr analog that regulates anaerobic respiration in Shewanella putrefaciens MR-1.

Q8NFD5	ARI1B_HUMAN	AT-rich interactive domain-containing protein 1B	11734557	SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones.

P00927	THDH_YEAST	Threonine dehydratase, mitochondrial	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

P38123	SWD3_YEAST	COMPASS component SWD3	11742990	The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4.

Q04742	EMX1_MOUSE	Homeobox protein EMX1	15147765	Emx1 and Emx2 cooperate in initial phase of archipallium development.

O74957	AGO1_SCHPO	Protein argonaute	17310250	Two different Argonaute complexes are required for siRNA generation and heterochromatin assembly in fission yeast.

Q9VVV9	NKD_DROME	Protein naked cuticle	11546742	Successive specification of Drosophila neuroblasts NB 6-4 and NB 7-3 depends on interaction of the segment polarity genes wingless, gooseberry and naked cuticle.

Q9XFM6	MSBP1_ARATH	Membrane steroid-binding protein 1	15608331	Arabidopsis membrane steroid binding protein 1 is involved in inhibition of cell elongation.

D0ZVG2	SSPH1_SALT1	E3 ubiquitin-protein ligase sspH1	18005683	Type III secretion effectors of the IpaH family are E3 ubiquitin ligases.

Q9BRL7	SC22C_HUMAN	Vesicle-trafficking protein SEC22c	9501016	Hsec22c: a homolog of yeast Sec22p and mammalian rsec22a and msec22b/ERS-24.

Q02928	CP4AB_HUMAN	Cytochrome P450 4A11	8274222	Complete cDNA sequence and cDNA-directed expression of CYP4A11, a fatty acid omega-hydroxylase expressed in human kidney.

O95786	DDX58_HUMAN	Probable ATP-dependent RNA helicase DDX58	16281057	SIKE is an IKK epsilon/TBK1-associated suppressor of TLR3- and virus- triggered IRF-3 activation pathways.

O01367	HOW_DROME	Protein held out wings	9118803	who encodes a KH RNA binding protein that functions in muscle development.

Q06593	OPT2_YEAST	Oligopeptide transporter 2	9643541	Schizosaccharomyces pombe isp4 encodes a transporter representing a novel family of oligopeptide transporters.

P46668	ATHB6_ARATH	Homeobox-leucine zipper protein ATHB-6	16055682	Homeodomain leucine zipper class I genes in Arabidopsis. Expression patterns and phylogenetic relationships.

Q9QZR9	CO4A4_MOUSE	Collagen alpha-4(IV) chain	7962065	Collagen IV alpha 3, alpha 4, and alpha 5 chains in rodent basal laminae: sequence, distribution, association with laminins, and developmental switches.

P97318	DAB1_MOUSE	Disabled homolog 1	12646221	Inhibition of ubiquitin ligase Siah-1A by disabled-1.

Q8GXF0	RA51C_ARATH	DNA repair protein RAD51 homolog 3	12139010	Molecular cloning and characterization of RAD51-like genes from Arabidopsis thaliana.

P91927	A60DA_DROME	LETM1 and EF-hand domain-containing protein anon-60Da, mitochondrial	10071211	Identification of nuclear genes encoding mitochondrial proteins: isolation of a collection of D. melanogaster cDNAs homologous to sequences in the Human Gene Index database.

P13725	ONCM_HUMAN	Oncostatin-M	2779549	Molecular cloning, sequence analysis, and functional expression of a novel growth regulator, oncostatin M.

P27939	AMY3C_ORYSJ	Alpha-amylase isozyme 3C	1714318	Characterization of an alpha-amylase multigene cluster in rice.

O15520	FGF10_HUMAN	Fibroblast growth factor 10	12591959	Structural basis by which alternative splicing confers specificity in fibroblast growth factor receptors.

P46309	GSH1_ARATH	Glutamate--cysteine ligase, chloroplastic	15610346	Differential targeting of GSH1 and GSH2 is achieved by multiple transcription initiation: implications for the compartmentation of glutathione biosynthesis in the Brassicaceae.

Q99PF4	CAD23_MOUSE	Cadherin-23	11138008	Mutations in Cdh23, encoding a new type of cadherin, cause stereocilia disorganization in waltzer, the mouse model for Usher syndrome type 1D.

Q13007	IL24_HUMAN	Interleukin-24	9826712	The cancer growth suppressor gene mda-7 selectively induces apoptosis in human breast cancer cells and inhibits tumor growth in nude mice.

P10959	EST2_RAT	Liver carboxylesterase 1	3235453	Molecular cloning and nucleotide sequence of cDNA of microsomal carboxyesterase E1 of rat liver.

P41995	ODD1_CAEEL	Zinc finger protein odd-1	14648222	Odd-skipped homologs function during gut development in C. elegans.

O95271	TNKS1_HUMAN	Tankyrase-1	9822378	Tankyrase, a poly(ADP-ribose) polymerase at human telomeres.

P67775	PP2AA_HUMAN	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform	2849764	The nucleotide sequence of the cDNA encoding the human lung protein phosphatase 2A alpha catalytic subunit.

P82003	PTSP_BOMMO	Prothoracicostatic peptide	10531308	Identification of a prothoracicostatic peptide in the larval brain of the silkworm, Bombyx mori.

Q9Y876	SHR3_SCHPO	Secretory component protein psh3	11069779	The SHR3 homologue from S. pombe demonstrates a conserved function of ER packaging chaperones.

Q9EQE1	SENP2_RAT	Sentrin-specific protease 2	10944533	Inhibition of Wnt signaling pathway by a novel Axin-binding protein.

P56473	AGRP_MOUSE	Agouti-related protein	9311920	Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein.

Q93356	HM37_CAEEL	Homeobox protein ceh-37	14536063	Otx/otd homeobox genes specify distinct sensory neuron identities in C. elegans.

P68401	PA1B2_BOVIN	Platelet-activating factor acetylhydrolase IB subunit beta	11522926	Preparation and crystal structure of the recombinant alpha(1)/alpha(2) catalytic heterodimer of bovine brain platelet- activating factor acetylhydrolase Ib.

Q9NB71	HIW_DROME	E3 ubiquitin-protein ligase highwire	10839352	Highwire regulates synaptic growth in Drosophila.

Q96QE2	MYCT_HUMAN	Proton myo-inositol cotransporter	11500374	Identification of a mammalian H(+)-myo-inositol symporter expressed predominantly in the brain.

Q60592	MAST2_MOUSE	Microtubule-associated serine/threonine-protein kinase 2	10404183	Interactions between beta 2-syntrophin and a family of microtubule- associated serine/threonine kinases.

Q9Y8A5	LNKS_ASPTE	Lovastatin nonaketide synthase	10381407	Lovastatin biosynthesis in Aspergillus terreus: characterization of blocked mutants, enzyme activities and a multifunctional polyketide synthase gene.

P62899	RL31_HUMAN	60S ribosomal protein L31	2780320	cDNA sequence of human ribosomal protein L31.

O15287	FANCG_HUMAN	Fanconi anemia group G protein	9806548	The Fanconi anaemia group G gene FANCG is identical with XRCC9.

O35923	BRCA2_RAT	Breast cancer type 2 susceptibility protein homolog	12228710	BRCA2 function in DNA binding and recombination from a BRCA2-DSS1- ssDNA structure.

Q9NYZ4	SIGL8_HUMAN	Sialic acid-binding Ig-like lectin 8	10625619	Siglec-8. A novel eosinophil-specific member of the immunoglobulin superfamily.

Q5DTL9	S4A10_MOUSE	Sodium-driven chloride bicarbonate exchanger	10993873	The Na+-driven Cl-/HCO3- exchanger. Cloning, tissue distribution, and functional characterization.

P35520	CBS_HUMAN	Cystathionine beta-synthase	11483494	Structure of human cystathionine beta-synthase: a unique pyridoxal 5'-phosphate-dependent heme protein.

P38852	LIN1_YEAST	Protein LIN1	12402242	Proteins interacting with Lin 1p, a putative link between chromosome segregation, mRNA splicing and DNA replication in Saccharomyces cerevisiae.

Q8IY92	SLX4_HUMAN	Structure-specific endonuclease subunit SLX4	19596236	Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases.

P87297	DAD1_SCHPO	DASH complex subunit dad1	16079914	Molecular analysis of kinetochore architecture in fission yeast.

O00444	PLK4_HUMAN	Serine/threonine-protein kinase PLK4	16244668	The Polo kinase Plk4 functions in centriole duplication.

Q99MI6	GIMA3_MOUSE	GTPase IMAP family member 3	11238997	Molecular cloning of Ian4: a BCR/ABL-induced gene that encodes an outer membrane mitochondrial protein with GTP-binding activity.

P29506	UNC4_CAEEL	Homeobox protein unc-4	7555714	Expression of the unc-4 homeoprotein in Caenorhabditis elegans motor neurons specifies presynaptic input.

Q08562	ULS1_YEAST	ATP-dependent helicase ULS1	9271422	Identification of a member of a DNA-dependent ATPase family that causes interference with silencing.

O15118	NPC1_HUMAN	Niemann-Pick C1 protein	12554680	Defective endocytic trafficking of NPC1 and NPC2 underlying infantile Niemann-Pick type C disease.

Q9ZU51	RHA2B_ARATH	Probable E3 ubiquitin-protein ligase RHA2B	12062802	A gene trap Dissociation insertion line, associated with a RING-H2 finger gene, shows tissue specific and developmental regulated expression of the gene in Arabidopsis.

P48432	SOX2_MOUSE	Transcription factor SOX-2	19740739	Zfp206, Oct4, and Sox2 are integrated components of a transcriptional regulatory network in embryonic stem cells.

Q68DX3	FRPD2_HUMAN	FERM and PDZ domain-containing protein 2	19706687	PDZ-domain-directed basolateral targeting of the peripheral membrane protein FRMPD2 in epithelial cells.

Q811H0	ZBT42_MOUSE	Zinc finger and BTB domain-containing protein 42	18262495	Co-localization of a novel transcriptional repressor simiRP58 with RP58.

Q94B78	GCSP2_ARATH	Glycine dehydrogenase [decarboxylating] 2, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

A0S864	NXACA_BOIIR	Irditoxin subunit A	18952712	Irditoxin, a novel covalently linked heterodimeric three-finger toxin with high taxon-specific neurotoxicity.

Q8LPQ9	FPA_ARATH	Flowering time control protein FPA	11402170	FPA, a gene involved in floral induction in Arabidopsis, encodes a protein containing RNA-recognition motifs.

Q9UMX1	SUFU_HUMAN	Suppressor of fused homolog	10564661	Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli.

Q12191	BUG1_YEAST	Binder of USO1 and GRH1 protein 1	14562095	Global analysis of protein localization in budding yeast.

P40060	IES5_YEAST	Ino eighty subunit 5	14562095	Global analysis of protein localization in budding yeast.

P37898	AAP1_YEAST	Alanine/arginine aminopeptidase	8100228	Isolation and characterization of AAP1. A gene encoding an alanine/arginine aminopeptidase in yeast.

P18911	RARG_MOUSE	Retinoic acid receptor gamma	15327771	Regulation of nuclear receptor activity by a pseudouridine synthase through posttranscriptional modification of steroid receptor RNA activator.

Q9JL19	NCOA6_MOUSE	Nuclear receptor coactivator 6	10788465	Isolation and characterization of peroxisome proliferator-activated receptor (PPAR) interacting protein (PRIP) as a coactivator for PPAR.

P69428	TATA_ECOLI	Sec-independent protein translocase protein tatA	11279240	TatB and TatC form a functional and structural unit of the twin- arginine translocase from Escherichia coli.

P36162	DAD2_YEAST	DASH complex subunit DAD2	15664196	Formation of a dynamic kinetochore-microtubule interface through assembly of the Dam1 ring complex.

P53886	APC1_YEAST	Anaphase-promoting complex subunit 1	8895471	Identification of subunits of the anaphase-promoting complex of Saccharomyces cerevisiae.

P49005	DPOD2_HUMAN	DNA polymerase delta subunit 2	8530069	Cloning of the cDNAs for the small subunits of bovine and human DNA polymerase delta and chromosomal location of the human gene (POLD2).

Q9QYE3	BC11A_MOUSE	B-cell lymphoma/leukemia 11A	10744719	Isolation of a novel family of C(2)H(2) zinc finger proteins implicated in transcriptional repression mediated by chicken ovalbumin upstream promoter transcription factor (COUP-TF) orphan nuclear receptors.

Q8LGE3	ARP6_ARATH	Actin-related protein 6	17220196	Repression of flowering in Arabidopsis requires activation of FLOWERING LOCUS C expression by the histone variant H2A.Z.

Q7Z2E3	APTX_HUMAN	Aprataxin	17276982	Actions of aprataxin in multiple DNA repair pathways.

Q99758	ABCA3_HUMAN	ATP-binding cassette sub-family A member 3	11718719	ABCA3 is a lamellar body membrane protein in human lung alveolar type II cells.

O02495	SYB1_CAEEL	Synaptobrevin-1	9412487	Synaptic transmission deficits in Caenorhabditis elegans synaptobrevin mutants.

P03889	NU1M_RAT	NADH-ubiquinone oxidoreductase chain 1	3399396	Nucleotide sequence of rat mitochondrial NADH dehydrogenase subunit 1. GTG, a new initiator codon in vertebrate mitochondrial genome.

P21127	CD11B_HUMAN	Cell division protein kinase 11B	10882096	Identification and characterization of a novel cell cycle-regulated internal ribosome entry site.

P32582	CBS_YEAST	Cystathionine beta-synthase	8366024	Cysteine biosynthesis in Saccharomyces cerevisiae occurs through the transsulfuration pathway which has been built up by enzyme recruitment.

Q13310	PABP4_HUMAN	Polyadenylate-binding protein 4	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

P43246	MSH2_HUMAN	DNA mismatch repair protein Msh2	19596235	Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair.

Q02933	RNY1_YEAST	Ribonuclease T2-like	11158587	Characterization of Rny1, the Saccharomyces cerevisiae member of the T2 RNase family of RNases: unexpected functions for ancient enzymes?

Q8WYN0	ATG4A_HUMAN	Cysteine protease ATG4A	15169837	LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation.

Q9NAN1	SAE2_CAEEL	SUMO-activating enzyme subunit uba-2	15107848	SUMO modification is required for in vivo Hox gene regulation by the Caenorhabditis elegans Polycomb group protein SOP-2.

O14638	ENPP3_HUMAN	Ectonucleotide pyrophosphatase/phosphodiesterase family member 3	9344668	Molecular cloning and chromosomal localization of PD-Ibeta (PDNP3), a new member of the human phosphodiesterase I genes.

Q9C000	NALP1_HUMAN	NACHT, LRR and PYD domains-containing protein 1	11076957	Molecular cloning and characterization of DEFCAP-L and -S, two isoforms of a novel member of the mammalian Ced-4 family of apoptosis proteins.

Q8N474	SFRP1_HUMAN	Secreted frizzled-related protein 1	9192640	Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action.

O54699	S29A2_RAT	Equilibrative nucleoside transporter 2	9353301	Molecular cloning and functional characterization of nitrobenzylthioinosine (NBMPR)-sensitive (es) and NBMPR-insensitive (ei) equilibrative nucleoside transporter proteins (rENT1 and rENT2) from rat tissues.

Q12386	ARP8_YEAST	Actin-like protein ARP8	12887900	Involvement of actin-related proteins in ATP-dependent chromatin remodeling.

Q01401	GLGB_ORYSJ	1,4-alpha-glucan-branching enzyme, chloroplastic/amyloplastic	8455548	Molecular analysis of the gene encoding a rice starch branching enzyme.

Q6NYU3	NDF6A_DANRE	Neurogenic differentiation factor 6-A	12044886	The functional specificity of NeuroD is defined by a single amino acid residue (N11) in the basic domain.

Q9UU87	PPK34_SCHPO	Serine/threonine-protein kinase ppk34	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q06592	HPA2_YEAST	Histone acetyltransferase HPA2	10600387	Crystal structure of the histone acetyltransferase Hpa2: a tetrameric member of the Gcn5-related N-acetyltransferase superfamily.

P22804	BET1_YEAST	Protein transport protein BET1	11001058	Topological restriction of SNARE-dependent membrane fusion.

Q12476	AIR2_YEAST	Protein AIR2	15935759	Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase.

P36131	SPC34_YEAST	DASH complex subunit SPC34	11799062	The mitotic spindle is required for loading of the DASH complex onto the kinetochore.

P07665	SRYB_DROME	Serendipity locus protein beta	1868833	Genomic targets of the serendipity beta and delta zinc finger proteins and their respective DNA recognition sites.

Q9SF15	PUB24_ARATH	E3 ubiquitin-protein ligase PUB24	18771922	Negative regulation of PAMP-triggered immunity by an E3 ubiquitin ligase triplet in Arabidopsis.

Q55GV9	LIMCH_DICDI	Calponin homology and LIM domain-containing protein	15962002	A Rab21/LIM-only/CH-LIM complex regulates phagocytosis via both activating and inhibitory mechanisms.

O70351	HCD2_RAT	3-hydroxyacyl-CoA dehydrogenase type-2	11023795	Recognition of structurally diverse substrates by type II 3- hydroxyacyl-CoA dehydrogenase (HADH II)/amyloid-beta binding alcohol dehydrogenase (ABAD).

P07948	LYN_HUMAN	Tyrosine-protein kinase Lyn	15173188	Trafficking of Lyn through the Golgi caveolin involves the charged residues on alphaE and alphaI helices in the kinase domain.

P16547	OM45_YEAST	Mitochondrial outer membrane protein OM45	11502169	Yeast mitochondrial dehydrogenases are associated in a supramolecular complex.

Q64364	CD2A2_MOUSE	Cyclin-dependent kinase inhibitor 2A, isoform 3	15567177	The ARF tumor suppressor inhibits BCL6-mediated transcriptional repression.

Q9S7N7	PSAG_ARATH	Photosystem I reaction center subunit V, chloroplastic	12766230	Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.

Q9HDZ6	DAM1_SCHPO	DASH complex subunit dam1	16079914	Molecular analysis of kinetochore architecture in fission yeast.

Q6AWJ9	PTK7_DROME	Tyrosine-protein kinase-like otk	15456725	The receptor tyrosine kinase Off-track is required for layer-specific neuronal connectivity in Drosophila.

Q12263	GIN4_YEAST	Serine/threonine-protein kinase GIN4	12058072	Cell cycle-dependent assembly of a Gin4-septin complex.

Q12451	OSH2_YEAST	Oxysterol-binding protein homolog 2	15173322	A role for yeast oxysterol-binding protein homologs in endocytosis and in the maintenance of intracellular sterol-lipid distribution.

P16970	ABCD3_RAT	ATP-binding cassette sub-family D member 3	1968461	The 70-kDa peroxisomal membrane protein is a member of the Mdr (P- glycoprotein)-related ATP-binding protein superfamily.

Q09769	LONM_SCHPO	Lon protease homolog, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q00534	CDK6_HUMAN	Cell division protein kinase 6	16548883	Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection.

Q15742	NAB2_HUMAN	NGFI-A-binding protein 2	8668170	NAB2, a corepressor of NGFI-A (Egr-1) and Krox20, is induced by proliferative and differentiative stimuli.

O15273	TELT_HUMAN	Telethonin	9350988	Telethonin, a novel sarcomeric protein of heart and skeletal muscle.

P43567	AGX1_YEAST	Alanine--glyoxylate aminotransferase 1	16226833	Crystal structure and confirmation of the alanine:glyoxylate aminotransferase activity of the YFL030w yeast protein.

Q54GD0	MGP1_DICDI	Mental retardation GTPase activating protein homolog 1	18334553	Dictyostelium MEGAPs: F-BAR domain proteins that regulate motility and membrane tubulation in contractile vacuoles.

P11796	SODM_NICPL	Superoxide dismutase [Mn], mitochondrial	2540959	The induction of manganese superoxide dismutase in response to stress in Nicotiana plumbaginifolia.

P32786	RRN6_YEAST	RNA polymerase I-specific transcription initiation factor RRN6	8702872	RRN11 encodes the third subunit of the complex containing Rrn6p and Rrn7p that is essential for the initiation of rDNA transcription by yeast RNA polymerase I.

P0AA37	RLUA_ECOLI	Ribosomal large subunit pseudouridine synthase A	7493321	A dual-specificity pseudouridine synthase: an Escherichia coli synthase purified and cloned on the basis of its specificity for psi 746 in 23S RNA is also specific for psi 32 in tRNA(phe).

Q27934	PHYL_DROME	Protein phyllopod	12215542	Phyllopod acts as an adaptor protein to link the sina ubiquitin ligase to the substrate protein tramtrack.

Q8IUC6	TCAM1_HUMAN	TIR domain-containing adapter molecule 1	14982987	Toll-like receptor 3-mediated activation of NF-kappaB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN- beta.

P25815	S100P_HUMAN	Protein S100-P	1633809	S100P, a novel Ca(2+)-binding protein from human placenta. cDNA cloning, recombinant protein expression and Ca2+ binding properties.

O00422	SAP18_HUMAN	Histone deacetylase complex subunit SAP18	9150135	Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex.

P03372	ESR1_HUMAN	Estrogen receptor	3753802	Sequence and expression of human estrogen receptor complementary DNA.

O74880	MCES_SCHPO	mRNA cap guanine-N7 methyltransferase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9STF3	PP265_ARATH	Pentatricopeptide repeat-containing protein At3g46790, chloroplastic	14617084	A nucleus-encoded factor, CRR2, is essential for the expression of chloroplast ndhB in Arabidopsis.

Q9UT24	BRR2_SCHPO	Pre-mRNA-splicing factor brr2	16133344	Multiple genetic and biochemical interactions of Brr2, Prp8, Prp31, Prp1 and Prp4 kinase suggest a function in the control of the activation of spliceosomes in Schizosaccharomyces pombe.

Q924Z4	LASS2_MOUSE	LAG1 longevity assurance homolog 2	15823095	Mammalian Lass6 and its related family members regulate synthesis of specific ceramides.

Q7KRY7	LAP4_DROME	Protein lap4	10884224	Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors.

Q06834	ASR1_YEAST	Alcohol-sensitive RING finger protein 1	15117954	Asr1p, a novel yeast ring/PHD finger protein, signals alcohol stress to the nucleus.

Q9Z0R9	FADS2_MOUSE	Fatty acid desaturase 2	9867867	Cloning, expression, and nutritional regulation of the mammalian Delta-6 desaturase.

Q9NFP1	VNNL1_DROME	Vanin-like protein 1	10501839	An ESTs description of the new vanin gene family conserved from fly to human.

P04090	REL2_HUMAN	Prorelaxin H2	6548702	Relaxin gene expression in human ovaries and the predicted structure of a human preprorelaxin by analysis of cDNA clones.

Q39131	LAML_ARATH	Lamin-like protein	14517339	Proteomic analysis of glycosylphosphatidylinositol-anchored membrane proteins.

O95685	PPR3D_HUMAN	Protein phosphatase 1 regulatory subunit 3D	9414128	PPP1R6, a novel member of the family of glycogen-targeting subunits of protein phosphatase 1.

P62917	RL8_HUMAN	60S ribosomal protein L8	7506540	Characterization by cDNA cloning of the mRNA of human ribosomal protein L8.

Q13107	UBP4_HUMAN	Ubiquitin carboxyl-terminal hydrolase 4	16472766	UnpEL/Usp4 is ubiquitinated by Ro52 and deubiquitinated by itself.

Q9P7S6	SNF30_SCHPO	SWI/SNF chromatin-remodeling complex subunit snf30	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O74435	CDC31_SCHPO	Cell division control protein 31	12857865	Fission yeast cdc31p is a component of the half-bridge and controls SPB duplication.

Q08605	GAGA_DROME	Transcription factor GAGA	8620838	The GAGA factor is required in the early Drosophila embryo not only for transcriptional regulation but also for nuclear division.

Q9UPT9	UBP22_HUMAN	Ubiquitin carboxyl-terminal hydrolase 22	18469533	USP22, an hSAGA subunit and potential cancer stem cell marker, reverses the polycomb-catalyzed ubiquitylation of histone H2A.

P40848	XRN2_SCHPO	5'-3' exoribonuclease 2	8190062	Molecular analysis of the dhp1+ gene of Schizosaccharomyces pombe: an essential gene that has homology to the DST2 and RAT1 genes of Saccharomyces cerevisiae.

O13881	CLR2_SCHPO	Cryptic loci regulator 2	17289569	SHREC, an effector complex for heterochromatic transcriptional silencing.

P55863	SOX3A_XENLA	Transcription factor Sox-3-A	9099866	The Xenopus Sox3 gene expressed in oocytes of early stages.

Q8JH92	PPD1A_XENLA	Blood vessel epicardial substance-A	20057356	Identification of a novel Bves function: regulation of vesicular transport.

Q7TN78	ACSM4_RAT	Acyl-coenzyme A synthetase ACSM4, mitochondrial	12709059	O-MACS, a novel member of the medium-chain acyl-CoA synthetase family, specifically expressed in the olfactory epithelium in a zone- specific manner.

Q9Z104	HM20B_MOUSE	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related	10486208	Cloning, chromosomal location, and expression analysis of murine Smarce1-related, a new member of the high-mobility 365 group gene family.

P82348	SGCG_MOUSE	Gamma-sarcoglycan	10448073	Developmental expression of sarcoglycan gene products in cultured myocytes.

Q63537	SYN2_RAT	Synapsin-2	2506642	Synapsins: mosaics of shared and individual domains in a family of synaptic vesicle phosphoproteins.

P37387	XYLF_ECOLI	D-xylose-binding periplasmic protein	8581399	Molecular genetics of a receptor protein for D-xylose, encoded by the gene xylF, in Escherichia coli.

Q99JY8	LPP3_MOUSE	Lipid phosphate phosphohydrolase 3	12925589	The lipid phosphatase LPP3 regulates extra-embryonic vasculogenesis and axis patterning.

Q5I2B2	AMP_AMARE	Antimicrobial peptide Ar-AMP	16126239	An antimicrobial peptide Ar-AMP from amaranth (Amaranthus retroflexus L.) seeds.

P26786	RS7A_YEAST	40S ribosomal protein S7-A	15590835	The small-subunit processome is a ribosome assembly intermediate.

Q39688	EP1G_DAUCA	Epidermis-specific secreted glycoprotein EP1	8275102	The carrot secreted glycoprotein gene EP1 is expressed in the epidermis and has sequence homology to Brassica S-locus glycoproteins.

Q8GWZ6	SRR1_ARATH	Protein SENSITIVITY TO RED LIGHT REDUCED 1	12533513	The Arabidopsis SRR1 gene mediates phyB signaling and is required for normal circadian clock function.

P53840	TOF1_YEAST	Topoisomerase 1-associated factor 1	12944972	S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication- pausing complex.

Q6DD88	ATLA3_HUMAN	Atlastin-3	18270207	Atlastin GTPases are required for Golgi apparatus and ER morphogenesis.

O43504	HBXIP_HUMAN	Hepatitis B virus X-interacting protein	9499022	Cloning and characterization of a novel hepatitis B virus x binding protein that inhibits viral replication.

Q8CFC9	LZTS1_RAT	Leucine zipper putative tumor suppressor 1	12415013	The postsynaptic density and dendritic raft localization of PSD- Zip70, which contains an N-myristoylation sequence and leucine-zipper motifs.

Q9XFM0	IAA28_ARATH	Auxin-responsive protein IAA28	11251090	A gain-of-function mutation in IAA28 suppresses lateral root development.

Q9VGI8	BLM_DROME	Bloom syndrome protein homolog	10049920	Evolution of the RECQ family of helicases: a Drosophila homolog, Dmblm, is similar to the human Bloom syndrome gene.

P78344	IF4G2_HUMAN	Eukaryotic translation initiation factor 4 gamma 2	9032289	DAP-5, a novel homolog of eukaryotic translation initiation factor 4G isolated as a putative modulator of gamma interferon-induced programmed cell death.

O15266	SHOX_HUMAN	Short stature homeobox protein	9259282	PHOG, a candidate gene for involvement in the short stature of Turner syndrome.

P32367	TFC1_YEAST	Transcription factor tau 95 kDa subunit	2052571	Isolation of TFC1, a gene encoding one of two DNA-binding subunits of yeast transcription factor tau (TFIIIC).

P20702	ITAX_HUMAN	Integrin alpha-X	2303426	Genomic structure of an integrin alpha subunit, the leukocyte p150,95 molecule.

Q8I8U2	AP1G_DICDI	AP-1 complex subunit gamma	12802059	The AP-1 clathrin-adaptor is required for lysosomal enzymes sorting and biogenesis of the contractile vacuole complex in Dictyostelium cells.

P01037	CYTN_HUMAN	Cystatin-SN	3446578	Human cysteine-proteinase inhibitors: nucleotide sequence analysis of three members of the cystatin gene family.

P21728	DRD1_HUMAN	D(1A) dopamine receptor	2168520	Cloning and expression of human and rat D1 dopamine receptors.

Q9ESP7	ATS4_RAT	A disintegrin and metalloproteinase with thrombospondin motifs 4	10961658	ADAMTS-4 (a disintegrin and metalloproteinase with thrombospondin motifs) is transcriptionally induced in beta-amyloid treated rat astrocytes.

Q9UBD6	RHCG_HUMAN	Ammonium transporter Rh type C	16580862	Ammonium transport properties of HEK293 cells expressing RhCG mutants: preliminary analysis of structure/function by site-directed mutagenesis.

Q54RP0	AGTA_DICDI	UDP-galactose:fucoside alpha-3-galactosyltransferase	15123660	Specificity of a soluble UDP-galactose:fucoside alpha1,3- galactosyltransferase that modifies the cytoplasmic glycoprotein Skp1 in Dictyostelium.

O43463	SUV91_HUMAN	Histone-lysine N-methyltransferase SUV39H1	10949293	Regulation of chromatin structure by site-specific histone H3 methyltransferases.

P33416	HSP78_YEAST	Heat shock protein 78, mitochondrial	7500331	The mitochondrial ClpB homolog Hsp78 cooperates with matrix Hsp70 in maintenance of mitochondrial function.

Q12453	YO112_YEAST	Uncharacterized protein YOR112W	14562095	Global analysis of protein localization in budding yeast.

P53043	PPT1_YEAST	Serine/threonine-protein phosphatase T	7925273	A novel human protein serine/threonine phosphatase, which possesses four tetratricopeptide repeat motifs and localizes to the nucleus.

Q63544	SYUG_RAT	Gamma-synuclein	7673161	Peripheral nervous system-specific genes identified by subtractive cDNA cloning.

P36598	THI1_SCHPO	Thiamine repressible genes regulatory protein thi1	16874521	Joint regulation of the nmt1 promoter and sporulation by Thi1 and Thi5 in Schizosaccharomyces pombe.

P07207	NOTCH_DROME	Neurogenic locus Notch protein	10935637	Glycosyltransferase activity of Fringe modulates Notch-Delta interactions.

Q8L633	RNZC_ARATH	Ribonuclease Z, chloroplastic	12032089	Assigning a function to a conserved group of proteins: the tRNA 3' - processing enzymes.

Q03674	PLB2_YEAST	Lysophospholipase 2	10497163	Characterization and function in vivo of two novel phospholipases B/lysophospholipases from Saccharomyces cerevisiae.

P26045	PTN3_HUMAN	Tyrosine-protein phosphatase non-receptor type 3	1648725	Isolation of a cDNA clone encoding a human protein-tyrosine phosphatase with homology to the cytoskeletal-associated proteins band 4.1, ezrin, and talin.

Q9S7Y7	XYL1_ARATH	Alpha-xylosidase	11402218	Cloning and expression pattern of a gene encoding an alpha-xylosidase active against xyloglucan oligosaccharides from Arabidopsis.

Q06561	UNC52_CAEEL	Basement membrane proteoglycan	10512861	Complex patterns of alternative splicing mediate the spatial and temporal distribution of perlecan/UNC-52 in Caenorhabditis elegans.

Q8N131	PORIM_HUMAN	Porimin	11481458	Molecular cloning of Porimin, a novel cell surface receptor mediating oncotic cell death.

O15455	TLR3_HUMAN	Toll-like receptor 3	9435236	A family of human receptors structurally related to Drosophila Toll.

O00409	FOXN3_HUMAN	Forkhead box protein N3	16102918	CHES1/FOXN3 interacts with Ski-interacting protein and acts as a transcriptional repressor.

P22803	TRX2_YEAST	Thioredoxin-2	9015301	A heterodimer of thioredoxin and I(B)2 cooperates with Sec18p (NSF) to promote yeast vacuole inheritance.

P84962	DIV35_CARDV	Bacteriocin divergicin M35	15541799	Purification, characterization and amino acid sequencing of divergicin M35: a novel class IIa bacteriocin produced by Carnobacterium divergens M35.

P18505	GBRB1_HUMAN	Gamma-aminobutyric acid receptor subunit beta-1	2465923	Sequence and expression of human GABAA receptor alpha 1 and beta 1 subunits.

Q9Y7X8	ARP5_SCHPO	Actin-like protein arp5	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9P7C5	CWF16_SCHPO	Cell cycle control protein cwf16	11884590	Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

P47025	MDV1_YEAST	Mitochondrial division protein 1	16407407	Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins.

Q9QZR8	PDZD2_RAT	PDZ domain-containing protein 2	12591166	Sensory neuron proteins interact with the intracellular domains of sodium channel NaV1.8.

P38035	RTCR_ECOLI	Transcriptional regulatory protein rtcR	9738023	Characterization of the Escherichia coli RNA 3'-terminal phosphate cyclase and its sigma54-regulated operon.

P51157	RAB28_HUMAN	Ras-related protein Rab-28	8647132	Alternative mRNA splicing of the novel GTPase Rab28 generates isoforms with different C-termini.

Q10059	CDC12_SCHPO	Cell division control protein 12	12796476	The fission yeast cytokinesis formin Cdc12p is a barbed end actin filament capping protein gated by profilin.

Q9H342	O51J1_HUMAN	Olfactory receptor 51J1	11121057	Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.

Q9LSS7	RUBP1_ARATH	NEDD8-specific protease 1	16920872	SUMO-conjugating and SUMO-deconjugating enzymes from Arabidopsis.

Q9JIL2	CCL28_MOUSE	C-C motif chemokine 28	10781587	Identification of a novel chemokine (CCL28), which binds CCR10 (GPR2).

P25555	GBP2_YEAST	Single-strand telomeric DNA-binding protein GBP2	12519786	Exposure of single-stranded telomeric DNA causes G2/M cell cycle arrest in Saccharomyces cerevisiae.

Q75JT4	GRLJ_DICDI	Metabotropic glutamate receptor-like protein J	17501984	GrlJ, a Dictyostelium GABAB-like receptor with roles in post- aggregation development.

Q9Y6M0	TEST_HUMAN	Testisin	10397266	Testisin, a new human serine proteinase expressed by premeiotic testicular germ cells and lost in testicular germ cell tumors.

P27305	GLUQ_ECOLI	Glutamyl-Q tRNA(Asp) synthetase	15150343	A minimalist glutamyl-tRNA synthetase dedicated to aminoacylation of the tRNAAsp QUC anticodon.

P60716	LIPA_ECOLI	Lipoyl synthase	15157071	Lipoyl synthase requires two equivalents of S-adenosyl-L-methionine to synthesize one equivalent of lipoic acid.

P50432	GLYC_CAEEL	Serine hydroxymethyltransferase	9497323	Serine hydroxymethyltransferase is maternally essential in Caenorhabditis elegans.

Q9SJM7	URH1_ARATH	Uridine nucleosidase 1	19293370	Uridine-ribohydrolase is a key regulator in the uridine degradation pathway of Arabidopsis.

Q09882	PRP45_SCHPO	Pre-mRNA-processing protein 45	11690648	Cyclophilins of a novel subfamily interact with SNW/SKIP coregulator in Dictyostelium discoideum and Schizosaccharomyces pombe.

P38128	SMP1_YEAST	Transcription factor SMP1	9121433	The Saccharomyces cerevisiae MADS-box transcription factor Rlm1 is a target for the Mpk1 mitogen-activated protein kinase pathway.

P48622	FAD3D_ARATH	Temperature-sensitive omega-3 fatty acid desaturase, chloroplastic	7846164	Cloning of a temperature-regulated gene encoding a chloroplast omega- 3 desaturase from Arabidopsis thaliana.

P16104	H2AX_HUMAN	Histone H2A.x	2587254	H2A.X. a histone isoprotein with a conserved C-terminal sequence, is encoded by a novel mRNA with both DNA replication type and polyA 3' processing signals.

Q6DHH7	LZIC_DANRE	Protein LZIC	15932753	LZIC regulates neuronal survival during zebrafish development.

O44386	ITA3_DROME	Integrin alpha-PS3	9409675	A novel alpha integrin subunit associates with betaPS and functions in tissue morphogenesis and movement during Drosophila development.

Q94AG2	SERK1_ARATH	Somatic embryogenesis receptor kinase 1	11509554	Role of threonines in the Arabidopsis thaliana somatic embryogenesis receptor kinase 1 activation loop in phosphorylation.

P40970	LCB2_YEAST	Serine palmitoyltransferase 2	20182505	Orm family proteins mediate sphingolipid homeostasis.

Q9W769	VEX1_XENLA	Homeobox protein vex1	10446269	A role for the homeobox gene Xvex-1 as part of the BMP-4 ventral signaling pathway.

P84907	VMLEA_BOTLC	Zinc metalloproteinase leucurolysin-A	16139412	Isolation and biochemical characterization of a fibrinolytic proteinase from Bothrops leucurus (white-tailed jararaca) snake venom.

P55318	FOXA3_HUMAN	Hepatocyte nuclear factor 3-gamma	9369482	The role of HNF1alpha, HNF3gamma, and cyclic AMP in glucose-6- phosphatase gene activation.

O94813	SLIT2_HUMAN	Slit homolog 2 protein	10864954	Slit2 is a repellent for retinal ganglion cell axons.

O74365	SOL1_SCHPO	SWI/SNF chromatin-remodeling complex subunit sol1	18622392	Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast.

O94598	SEC5_SCHPO	Exocyst complex component sec5	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P53297	PBP1_YEAST	PAB1-binding protein 1	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P41814	TRM6_YEAST	tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6	9851972	The essential Gcd10p-Gcd14p nuclear complex is required for 1- methyladenosine modification and maturation of initiator methionyl- tRNA.

P46093	GPR4_HUMAN	G-protein coupled receptor 4	7498459	Cloning, sequencing and tissue distribution of two related G protein- coupled receptor candidates expressed prominently in human lung tissue.

Q9BZK7	TBL1R_HUMAN	F-box-like/WD repeat-containing protein TBL1XR1	12628926	Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1.

Q6J1H4	UTF1_MOUSE	Undifferentiated embryonic cell transcription factor 1	9524124	UTF1, a novel transcriptional coactivator expressed in pluripotent embryonic stem cells and extra-embryonic cells.

P42935	ELP2_YEAST	Elongator complex protein 2	11689709	Characterization of a six-subunit holo-elongator complex required for the regulated expression of a group of genes in Saccharomyces cerevisiae.

P28676	GRAN_HUMAN	Grancalcin	1530588	Isolation and characterization of grancalcin, a novel 28 kDa EF-hand calcium-binding protein from human neutrophils.

O60150	YNSK_SCHPO	Uncharacterized protein C18H10.20c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O43114	ORC5_SCHPO	Origin recognition complex subunit 5	10535928	Identification and reconstitution of the origin recognition complex from Schizosaccharomyces pombe.

Q39250	ADF1_ARATH	Actin-depolymerizing factor 1	11402164	ADF proteins are involved in the control of flowering and regulate F- actin organization, cell expansion, and organ growth in Arabidopsis.

Q92820	GGH_HUMAN	Gamma-glutamyl hydrolase	11005824	Molecular modeling and site-directed mutagenesis define the catalytic motif in human gamma -glutamyl hydrolase.

P51159	RB27A_HUMAN	Ras-related protein Rab-27A	15548590	Munc13-4 is an effector of rab27a and controls secretion of lysosomes in hematopoietic cells.

Q05932	FOLC_HUMAN	Folylpolyglutamate synthase, mitochondrial	1409616	Expression cloning of a human cDNA encoding folylpoly(gamma- glutamate) synthetase and determination of its primary structure.

Q8NFJ6	PKR2_HUMAN	Prokineticin receptor 2	12427552	Molecular cloning and characterization of prokineticin receptors.

O95749	GGPPS_HUMAN	Geranylgeranyl pyrophosphate synthase	10026212	Human geranylgeranyl diphosphate synthase. cDNA cloning and expression.

P38788	SSZ1_YEAST	Ribosome-associated complex subunit SSZ1	11054575	Yeast Pdr13p and Zuo1p molecular chaperones are new functional Hsp70 and Hsp40 partners.

Q59MN0	VAC8_CANAL	Vacuolar protein 8	16467476	Candida albicans VAC8 is required for vacuolar inheritance and normal hyphal branching.

Q24418	NMDA1_DROME	Glutamate [NMDA] receptor subunit 1	15823532	NMDA receptors mediate olfactory learning and memory in Drosophila.

Q8CF94	RHD_MOUSE	Blood group Rh(D) polypeptide	10329015	Characterization of the mouse Rh blood group gene.

P85508	CBG95_UNIPI	Calcium-binding shell glycoprotein P95	18810748	Nacre calcification in the freshwater mussel Unio pictorum: carbonic anhydrase activity and purification of a 95 kDa calcium-binding glycoprotein.

P22282	22P1_RAT	Cystatin-related protein 1	2477055	Primary structure and androgen regulation of a 20-kilodalton protein specific to rat ventral prostate.

P07250	IPMK_YEAST	Inositol polyphosphate multikinase	10574768	Synthesis of diphosphoinositol pentakisphosphate by a newly identified family of higher inositol polyphosphate kinases.

Q24423	NOC_DROME	Zinc finger protein Noc	12117809	Elbow and Noc define a family of zinc finger proteins controlling morphogenesis of specific tracheal branches.

Q9QZT0	CUZD1_RAT	CUB and zona pellucida-like domain-containing protein 1	11416020	Induction of UO-44 gene expression by tamoxifen in the rat uterus and ovary.

P98131	LYAM1_BOVIN	L-selectin	1371468	Characterization of the bovine peripheral lymph node homing receptor: a lectin cell adhesion molecule (LECAM).

Q68DV7	RNF43_HUMAN	RING finger protein 43	18313049	A cancer-associated RING finger protein, RNF43, is a ubiquitin ligase that interacts with a nuclear protein, HAP95.

P18962	DAP2_YEAST	Dipeptidyl aminopeptidase B	2647766	Structure, biosynthesis, and localization of dipeptidyl aminopeptidase B, an integral membrane glycoprotein of the yeast vacuole.

P15731	UBC4_YEAST	Ubiquitin-conjugating enzyme E2 4	11788821	A transmembrane ubiquitin ligase required to sort membrane proteins into multivesicular bodies.

Q8WYB5	MYST4_HUMAN	Histone acetyltransferase MYST4	10497217	Identification of a human histone acetyltransferase related to monocytic leukemia zinc finger protein.

Q9GZQ4	NMUR2_HUMAN	Neuromedin-U receptor 2	10887190	Identification and functional characterization of a novel subtype of neuromedin U receptor.

Q6UB35	C1TM_HUMAN	Monofunctional C1-tetrahydrofolate synthase, mitochondrial	12937168	Human mitochondrial C1-tetrahydrofolate synthase: gene structure, tissue distribution of the mRNA, and immunolocalization in Chinese hamster ovary calls.

Q9Y587	AP4S1_HUMAN	AP-4 complex subunit sigma-1	10436028	Characterization of a fourth adaptor-related protein complex.

P30838	AL3A1_HUMAN	Aldehyde dehydrogenase, dimeric NADP-preferring	1737758	Human stomach aldehyde dehydrogenase cDNA and genomic cloning, primary structure, and expression in Escherichia coli.

P31373	CYS3_YEAST	Cystathionine gamma-lyase	1577698	Cloning and characterization of the CYS3 (CYI1) gene of Saccharomyces cerevisiae.

Q12462	PEX11_YEAST	Peroxisomal membrane protein PMP27	7860627	Giant peroxisomes in oleic acid-induced Saccharomyces cerevisiae lacking the peroxisomal membrane protein Pmp27p.

O00626	CCL22_HUMAN	C-C motif chemokine 22	9151897	Human macrophage-derived chemokine (MDC), a novel chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells.

Q07666	KHDR1_HUMAN	KH domain-containing, RNA-binding, signal transduction-associated protein 1	1374686	Molecular cloning and nucleic acid binding properties of the GAP- associated tyrosine phosphoprotein p62.

P57093	PAHX_RAT	Phytanoyl-CoA dioxygenase, peroxisomal	10588950	Phytanoyl-CoA hydroxylase from rat liver: protein purification and cDNA cloning with implications for the subcellular localization of phytanic acid alpha-oxidation.

O35235	TNF11_MOUSE	Tumor necrosis factor ligand superfamily member 11	9367155	A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function.

P46679	STB2_YEAST	Protein STB2	9393435	Identification of the Saccharomyces cerevisiae genes STB1-STB5 encoding Sin3p binding proteins.

O60869	EDF1_HUMAN	Endothelial differentiation-related factor 1	9813014	EDF-1, a novel gene product down-regulated in human endothelial cell differentiation.

Q8S8E3	PYL6_ARATH	Abscisic acid receptor PYL6	19874541	PYR/PYL/RCAR family members are major in-vivo ABI1 protein phosphatase 2C-interacting proteins in Arabidopsis.

Q01196	RUNX1_HUMAN	Runt-related transcription factor 1	10207087	Functional and physical interactions between AML1 proteins and an ETS protein, MEF: implications for the pathogenesis of t(8;21)-positive leukemias.

Q9CWV6	PKRI1_MOUSE	PRKR-interacting protein 1	12679338	C114 is a novel IL-11-inducible nuclear double-stranded RNA-binding protein that inhibits protein kinase R.

P63149	UBE2B_RAT	Ubiquitin-conjugating enzyme E2 B	8048511	14-kDa ubiquitin-conjugating enzyme: structure of the rat gene and regulation upon fasting and by insulin.

P84685	SC43_TITCA	Toxin Tc43	15025998	Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

O14034	YEMD_SCHPO	Uncharacterized lyase C29B12.13	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P68403	KPCB_RAT	Protein kinase C beta type	3345563	Overproduction of protein kinase C causes disordered growth control in rat fibroblasts.

P05155	IC1_HUMAN	Plasma protease C1 inhibitor	2365061	Identification of a new P1 residue mutation (444Arg-->Ser) in a dysfunctional C1 inhibitor protein contained in a type II hereditary angioedema plasma.

Q9BZZ5	API5_HUMAN	Apoptosis inhibitor 5	10780674	AAC-11 overexpression induces invasion and protects cervical cancer cells from apoptosis.

Q9QZN0	FBX15_MOUSE	F-box only protein 15	12665572	Fbx15 is a novel target of Oct3/4 but is dispensable for embryonic stem cell self-renewal and mouse development.

Q9Y1J3	PDPK1_CAEEL	3-phosphoinositide-dependent protein kinase 1	10364160	A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans.

Q7LKV1	YK98_SCHPO	Uncharacterized protein C20H4.08	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q5HZG4	TAF3_MOUSE	Transcription initiation factor TFIID subunit 3	11438666	The TFIID components human TAFII140 and Drosophila BIP2 (TAFII155) are novel metazoan homologues of yeast TAFII47 containing a histone fold and a PHD finger.

Q9UTM3	RPN5_SCHPO	26S proteasome regulatory subunit rpn5	12783882	Rpn5 is a conserved proteasome subunit and required for proper proteasome localization and assembly.

Q9FT54	GTE6_ARATH	Transcription factor GTE6	16166385	The bromodomain protein GTE6 controls leaf development in Arabidopsis by histone acetylation at ASYMMETRIC LEAVES1.

Q9H8E8	CSR2B_HUMAN	Cysteine-rich protein 2-binding protein	10924333	The cysteine- and glycine-rich LIM domain protein CRP2 specifically interacts with a novel human protein.

P63329	PP2BA_RAT	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	1322410	Characterization of the phosphatase activity of a baculovirus- expressed calcineurin A isoform.

O08710	THYG_MOUSE	Thyroglobulin	9707574	A single amino acid change in the acetylcholinesterase-like domain of thyroglobulin causes congenital goiter with hypothyroidism in the cog/cog mouse: a model of human endoplasmic reticulum storage diseases.

Q90ZY4	SBK1_DANRE	Serine/threonine-protein kinase SBK1	16403448	Expression and characterization of a brain-specific protein kinase BSK146 from zebrafish.

Q06208	RIF2_YEAST	Protein RIF2	9087429	A novel Rap1p-interacting factor, Rif2p, cooperates with Rif1p to regulate telomere length in Saccharomyces cerevisiae.

Q7ZY18	MC6ZB_XENLA	Zygotic DNA replication licensing factor mcm6-B	9512418	Developmental regulation of MCM replication factors in Xenopus laevis.

Q69ZR2	HECD1_MOUSE	E3 ubiquitin-protein ligase HECTD1	17442300	The Hectd1 ubiquitin ligase is required for development of the head mesenchyme and neural tube closure.

Q15904	VAS1_HUMAN	V-type proton ATPase subunit S1	8733135	Long-range sequence analysis in Xq28: thirteen known and six candidate genes in 219.4 kb of high GC DNA between the RCP/GCP and G6PD loci.

Q9NXV6	CARF_HUMAN	CDKN2A-interacting protein	12581788	A novel putative collaborator of p19ARF.

Q12156	AIM7_YEAST	Protein AIM7	14562095	Global analysis of protein localization in budding yeast.

P37727	RAE1_RAT	Rab proteins geranylgeranyltransferase component A 1	8513495	cDNA cloning of component A of Rab geranylgeranyl transferase and demonstration of its role as a Rab escort protein.

Q04338	VTI1_YEAST	t-SNARE VTI1	9199167	The yeast v-SNARE Vti1p mediates two vesicle transport pathways through interactions with the t-SNAREs Sed5p and Pep12p.

P50586	TUB_MOUSE	Tubby protein	19837063	Identification of tubby and tubby-like protein 1 as eat-me signals by phage display.

Q13889	TF2H3_HUMAN	General transcription factor IIH subunit 3	9852112	Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.

Q16576	RBBP7_HUMAN	Histone-binding protein RBBP7	9150135	Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex.

P36032	MCH2_YEAST	Probable transporter MCH2	11536335	The putative monocarboxylate permeases of the yeast Saccharomyces cerevisiae do not transport monocarboxylic acids across the plasma membrane.

P13569	CFTR_HUMAN	Cystic fibrosis transmembrane conductance regulator	11707463	A Golgi-associated PDZ domain protein modulates cystic fibrosis transmembrane regulator plasma membrane expression.

O28029	SYA_ARCFU	Alanyl-tRNA synthetase	17327676	Structure of the AlaX-M trans-editing enzyme from Pyrococcus horikoshii.

P50462	CSRP3_MOUSE	Cysteine and glycine-rich protein 3	18258855	PICOT attenuates cardiac hypertrophy by disrupting calcineurin-NFAT signaling.

P00519	ABL1_HUMAN	Tyrosine-protein kinase ABL1	9144171	Protein binding and signaling properties of RIN1 suggest a unique effector function.

O13838	NUP40_SCHPO	Nucleoporin nup40	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P42776	GBF3_ARATH	G-box-binding factor 3	8672884	Transcription factor veracity: is GBF3 responsible for ABA-regulated expression of Arabidopsis Adh?

Q9USM8	ATG20_SCHPO	Autophagy-related protein 20	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q5NB25	IAA3_ORYSJ	Auxin-responsive protein IAA3	16200395	Structure and expression analysis of early auxin-responsive Aux/IAA gene family in rice (Oryza sativa).

Q8N441	FGRL1_HUMAN	Fibroblast growth factor receptor-like 1	12813049	Characterization of FGFRL1, a novel fibroblast growth factor (FGF) receptor preferentially expressed in skeletal tissues.

Q9FE59	SUC4_ARATH	Sucrose transport protein SUC4	10948254	A new subfamily of sucrose transporters, SUT4, with low affinity/high capacity localized in enucleate sieve elements of plants.

P04049	RAF1_HUMAN	RAF proto-oncogene serine/threonine-protein kinase	8756332	Ras/Rap effector specificity determined by charge reversal.

Q8VDD9	PHIP_MOUSE	PH-interacting protein	17636024	Identification of a WD40 repeat-containing isoform of PHIP as a novel regulator of beta-cell growth and survival.

Q9QYE3	BC11A_MOUSE	B-cell lymphoma/leukemia 11A	18681895	BCL11A is a SUMOylated protein and recruits SUMO-conjugation enzymes in its nuclear body.

Q8K480	MFRP_MOUSE	Membrane frizzled-related protein	12140190	Mfrp, a gene encoding a frizzled related protein, is mutated in the mouse retinal degeneration 6.

O75376	NCOR1_HUMAN	Nuclear receptor corepressor 1	12590135	The histone deacetylase 9 gene encodes multiple protein isoforms.

P92186	LIN28_CAEEL	Protein lin-28	9054503	The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA.

Q8IZQ8	MYCD_HUMAN	Myocardin	12397177	Potentiation of serum response factor activity by a family of myocardin-related transcription factors.

P14956	CECB_DROME	Cecropin-B	2104802	The cecropin locus in Drosophila; a compact gene cluster involved in the response to infection.

Q95YL4	PEFB_DICDI	Penta-EF hand domain-containing protein 2	11481037	Identification and characterization of two penta-EF-hand Ca(2+)- binding proteins in Dictyostelium discoideum.

Q9UQ84	EXO1_HUMAN	Exonuclease 1	11842105	Molecular interactions of human Exo1 with DNA.

Q9NSD7	RL3R1_HUMAN	Relaxin-3 receptor 1	10806363	The novel G-protein coupled receptor SALPR shares sequence similarity with somatostatin and angiotensin receptors.

P20292	AL5AP_HUMAN	Arachidonate 5-lipoxygenase-activating protein	8245774	5-lipoxygenase and 5-lipoxygenase-activating protein are localized in the nuclear envelope of activated human leukocytes.

Q99P82	CLD11_RAT	Claudin-11	11316752	Transforming growth factor-beta3 perturbs the inter-Sertoli tight junction permeability barrier in vitro possibly mediated via its effects on occludin, zonula occludens-1, and claudin-11.

P25285	GCST_BOVIN	Aminomethyltransferase, mitochondrial	2002038	Isolation and sequence determination of cDNA encoding T-protein of the glycine cleavage system.

O43670	ZN207_HUMAN	Zinc finger protein 207	9799612	ZNF207, a ubiquitously expressed zinc finger gene on chromosome 6p21.3.

Q01130	SRSF2_HUMAN	Serine/arginine-rich splicing factor 2	9447963	Sip1, a novel RS domain-containing protein essential for pre-mRNA splicing.

P27801	PEP3_YEAST	Vacuolar membrane protein PEP3	16601699	Purification of active HOPS complex reveals its affinities for phosphoinositides and the SNARE Vam7p.

P55209	NP1L1_HUMAN	Nucleosome assembly protein 1-like 1	8297347	Molecular characterization of hNRP, a cDNA encoding a human nucleosome-assembly-protein-I-related gene product involved in the induction of cell proliferation.

O94921	CDK14_HUMAN	Cell division protein kinase 14	17517622	Functional characterization of human PFTK1 as a cyclin-dependent kinase.

P21705	DAL82_YEAST	Protein DAL82	1898922	DAL82, a second gene required for induction of allantoin system gene transcription in Saccharomyces cerevisiae.

Q8BUN5	SMAD3_MOUSE	Mothers against decapentaplegic homolog 3	17467076	PRDM16/MEL1: a novel Smad binding protein expressed in murine embryonic orofacial tissue.

P36200	LHX3_XENLA	LIM/homeobox protein Lhx3	12874135	Selective degradation of excess Ldb1 by Rnf12/RLIM confers proper Ldb1 expression levels and Xlim-1/Ldb1 stoichiometry in Xenopus organizer functions.

Q9UL62	TRPC5_HUMAN	Short transient receptor potential channel 5	20164195	The phospholipid-binding protein SESTD1 is a novel regulator of the transient receptor potential channels TRPC4 and TRPC5.

O35134	RPA1_MOUSE	DNA-directed RNA polymerase I subunit RPA1	9236775	Molecular cloning and characterization of the cDNA encoding the largest subunit of mouse RNA polymerase I.

P92948	CDC5L_ARATH	Cell division cycle 5-like protein	17575050	Regulation of plant innate immunity by three proteins in a complex conserved across the plant and animal kingdoms.

P0A8H3	ZUPT_ECOLI	Zinc transporter zupT	11790762	ZupT is a Zn(II) uptake system in Escherichia coli.

O08919	NUMBL_MOUSE	Numb-like protein	12410312	Progenitor cell maintenance requires numb and numblike during mouse neurogenesis.

O13726	YDO6_SCHPO	Uncharacterized Na(+)/H(+) antiporter C15A10.06	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q28GD5	SOX7_XENTR	Transcription factor Sox-7	18472403	A functional screen for genes involved in Xenopus pronephros development.

Q8BYR5	CAPS2_MOUSE	Calcium-dependent secretion activator 2	14715936	The secretory granule-associated protein CAPS2 regulates neurotrophin release and cell survival.

P49597	P2C56_ARATH	Protein phosphatase 2C 56	9537523	ABI1 of Arabidopsis is a protein serine/threonine phosphatase highly regulated by the proton and magnesium ion concentration.

Q8TEB1	DCA11_HUMAN	DDB1- and CUL4-associated factor 11	16949367	A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1.

Q29983	MICA_HUMAN	MHC class I polypeptide-related sequence A	15995699	The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor.

Q9NZN1	IRPL1_HUMAN	Interleukin-1 receptor accessory protein-like 1	12783849	IL1 receptor accessory protein like, a protein involved in X-linked mental retardation, interacts with Neuronal Calcium Sensor-1 and regulates exocytosis.

Q86UA6	RIP_HUMAN	RPA-interacting protein	16135809	Sumoylation of the novel protein hRIPbeta is involved in replication protein A deposition in PML nuclear bodies.

Q9ERB4	CSPG2_RAT	Versican core protein	10397680	Versican/PG-M isoforms in vascular smooth muscle cells.

Q9USR4	REC27_SCHPO	Meiotic recombination protein rec27	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P34042	GPA4_DICDI	Guanine nucleotide-binding protein alpha-4 subunit	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q9Z244	GMPR1_RAT	GMP reductase 1	9813009	The guanosine monophosphate reductase gene is conserved in rats and its expression increases rapidly in brown adipose tissue during cold exposure.

P32266	MGM1_YEAST	Dynamin-like GTPase MGM1, mitochondrial	12808034	Mgm1p, a dynamin-related GTPase, is essential for fusion of the mitochondrial outer membrane.

Q09637	CYP9_CAEEL	Peptidyl-prolyl cis-trans isomerase 9	9407005	Cyclophilin and protein disulfide isomerase genes are co-transcribed in a functionally related manner in Caenorhabditis elegans.

P29846	POLG_HCVTW	Genome polyprotein	10675342	Hepatitis C virus core protein-induced loss of LZIP function correlates with cellular transformation.

P60892	PRPS1_RAT	Ribose-phosphate pyrophosphokinase 1	2822704	Nucleotide and deduced amino acid sequences of two distinct cDNAs for rat phosphoribosylpyrophosphate synthetase.

P61927	RL37_HUMAN	60S ribosomal protein L37	7545944	Human ribosomal protein L37 has motifs predicting serine/threonine phosphorylation and a zinc-finger domain.

Q02979	GDE1_YEAST	Glycerophosphodiester phosphodiesterase GDE1	14562095	Global analysis of protein localization in budding yeast.

Q62915	CSKP_RAT	Peripheral plasma membrane protein CASK	12641734	CIP98, a novel PDZ domain protein, is expressed in the central nervous system and interacts with calmodulin-dependent serine kinase.

P82966	IVBIC_OPHHA	Venom chymotrypsin inhibitor	11350064	Purification and characterization of a chymotrypsin inhibitor from the venom of Ophiophagus hannah (King Cobra).

O60120	YH76_SCHPO	Uncharacterized protein C16G5.06	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Z252	LIN7B_RAT	Protein lin-7 homolog B	10362251	Isolation and characterization of mammalian homologues of Caenorhabditis elegans lin-7: localization at cell-cell junctions.

Q15561	TEAD4_HUMAN	Transcriptional enhancer factor TEF-3	18579750	TEAD mediates YAP-dependent gene induction and growth control.

B2ZXD5	GPHR_CRIGR	Golgi pH regulator	18794847	GPHR is a novel anion channel critical for acidification and functions of the Golgi apparatus.

P42826	XKS1_YEAST	Xylulose kinase	14562095	Global analysis of protein localization in budding yeast.

Q8L7T3	UBC20_ARATH	Ubiquitin-conjugating enzyme E2 20	12427990	Molecular characterization of plant ubiquitin-conjugating enzymes belonging to the UbcP4/E2-C/UBCx/UbcH10 gene family.

Q15154	PCM1_HUMAN	Pericentriolar material 1 protein	14520415	Basal body dysfunction is a likely cause of pleiotropic Bardet-Biedl syndrome.

Q10468	B4GN1_RAT	Beta-1,4 N-acetylgalactosaminyltransferase 1	7980468	Beta-1,4-N-acetylgalactosaminyltransferase can synthesize both asialoglycosphingolipid GM2 and glycosphingolipid GM2 in vitro and in vivo: isolation and characterization of a beta-1,4-N- acetylgalactosaminyltransferase cDNA clone from rat ascites hepatoma cell line AH7974F.

Q9Z273	TULP1_MOUSE	Tubby-related protein 1	19837063	Identification of tubby and tubby-like protein 1 as eat-me signals by phage display.

Q8VD75	HIP1_MOUSE	Huntingtin-interacting protein 1	11604514	Huntingtin interacting protein 1 is a clathrin coat binding protein required for differentiation of late spermatogenic progenitors.

P57752	ACBP6_ARATH	Acyl-CoA-binding domain-containing protein 6	8660683	Characterization of an acyl-CoA-binding protein from Arabidopsis thaliana.

P38061	RL32_YEAST	60S ribosomal protein L32	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q9P7S3	SSR3_SCHPO	SWI/SNF and RSC complexes subunit ssr3	18622392	Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast.

P13186	KIN2_YEAST	Serine/threonine-protein kinase KIN2	8020610	KIN1 and KIN2 protein kinases localize to the cytoplasmic face of the yeast plasma membrane.

P32785	FMT_YEAST	Methionyl-tRNA formyltransferase, mitochondrial	10781559	Initiation of protein synthesis in Saccharomyces cerevisiae mitochondria without formylation of the initiator tRNA.

O15126	SCAM1_HUMAN	Secretory carrier-associated membrane protein 1	15840657	Secretory carrier membrane proteins interact and regulate trafficking of the organellar (Na+,K+)/H+ exchanger NHE7.

Q9NUX5	POTE1_HUMAN	Protection of telomeres protein 1	16166375	Shelterin: the protein complex that shapes and safeguards human telomeres.

Q8CEE0	CEP57_MOUSE	Centrosomal protein of 57 kDa	12717444	Translokin is an intracellular mediator of FGF-2 trafficking.

Q02948	VPS30_YEAST	Vacuolar protein sorting-associated protein 30	12244127	Retromer function in endosome-to-Golgi retrograde transport is regulated by the yeast Vps34 PtdIns 3-kinase.

Q99JP6	HOME3_MOUSE	Homer protein homolog 3	9808458	Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins.

P08727	K1C19_HUMAN	Keratin, type I cytoskeletal 19	2448790	Sequence of the human 40-kDa keratin reveals an unusual structure with very high sequence identity to the corresponding bovine keratin.

O70596	IRK14_RAT	ATP-sensitive inward rectifier potassium channel 14	9592090	Kir2.4: a novel K+ inward rectifier channel associated with motoneurons of cranial nerve nuclei.

P09938	RIR2_YEAST	Ribonucleoside-diphosphate reductase small chain 1	10535923	Purification of ribonucleotide reductase subunits Y1, Y2, Y3, and Y4 from yeast: Y4 plays a key role in diiron cluster assembly.

Q16595	FRDA_HUMAN	Frataxin, mitochondrial	20053667	Molecular control of the cytosolic aconitase/IRP1 switch by extramitochondrial frataxin.

P32561	RPD3_YEAST	Histone deacetylase RPD3	12110674	A conserved motif common to the histone acetyltransferase Esa1 and the histone deacetylase Rpd3.

P28789	HEM3_YEAST	Porphobilinogen deaminase	1508149	Structure and regulation of yeast HEM3, the gene for porphobilinogen deaminase.

Q9Y3Z3	SAMH1_HUMAN	SAM domain and HD domain-containing protein 1	19525956	Mutations involved in Aicardi-Goutieres syndrome implicate SAMHD1 as regulator of the innate immune response.

Q96AB3	ISOC2_HUMAN	Isochorismatase domain-containing protein 2, mitochondrial	17658461	Identification and characterization of a novel protein ISOC2 that interacts with p16INK4a.

Q9V3S9	BGM_DROME	Very long-chain-fatty-acid--CoA ligase bubblegum	10373116	Preventing neurodegeneration in the Drosophila mutant bubblegum.

Q15744	CEBPE_HUMAN	CCAAT/enhancer-binding protein epsilon	8661101	A novel human CCAAT/enhancer binding protein gene, C/EBPepsilon, is expressed in cells of lymphoid and myeloid lineages and is localized on chromosome 14q11.2 close to the T-cell receptor alpha/delta locus.

O14002	MAK2_SCHPO	Peroxide stress-activated histidine kinase mak2	11758939	Genetic analysis of the His-to-Asp phosphorelay implicated in mitotic cell cycle control: involvement of histidine-kinase genes of Schizosaccharomyces pombe.

P38324	SLX1_YEAST	Structure-specific endonuclease subunit SLX1	12832395	Slx1-Slx4 is a second structure-specific endonuclease functionally redundant with Sgs1-Top3.

Q9V4Z9	LINES_DROME	Protein lines	14568103	The Drm-Bowl-Lin relief-of-repression hierarchy controls fore- and hindgut patterning and morphogenesis.

Q12460	NOP56_YEAST	Nucleolar protein 56	9372940	Nucleolar KKE/D repeat proteins Nop56p and Nop58p interact with Nop1p and are required for ribosome biogenesis.

Q8K3T4	FFAR1_RAT	Free fatty acid receptor 1	12496284	The orphan G protein-coupled receptor GPR40 is activated by medium and long-chain fatty acids.

Q04228	UBX2_YEAST	UBX domain-containing protein 2	16179953	Ubx2 links the Cdc48 complex to ER-associated protein degradation.

Q17336	CWC22_CAEEL	Pre-mRNA-splicing factor CWC22 homolog	9136012	Distinct requirements for somatic and germline expression of a generally expressed Caernorhabditis elegans gene.

Q9NIP6	CP2B_DROME	Cardio acceleratory peptide 2b	11959669	Two nitridergic peptides are encoded by the gene capability in Drosophila melanogaster.

Q13635	PTC1_HUMAN	Protein patched homolog 1	8981943	Most germ-line mutations in the nevoid basal cell carcinoma syndrome lead to a premature termination of the PATCHED protein, and no genotype-phenotype correlations are evident.

Q765I2	UTS2B_RAT	Urotensin-2B	14550283	Identification of urotensin II-related peptide as the urotensin II- immunoreactive molecule in the rat brain.

Q00947	STP1_YEAST	Transcription factor STP1	10648791	Stp1p, Stp2p and Abf1p are involved in regulation of expression of the amino acid transporter gene BAP3 of Saccharomyces cerevisiae.

Q9XFT3	PSBQ1_ARATH	Oxygen-evolving enhancer protein 3-1, chloroplastic	11826309	Central functions of the lumenal and peripheral thylakoid proteome of Arabidopsis determined by experimentation and genome-wide prediction.

P32657	CHD1_YEAST	Chromo domain-containing protein 1	16468993	The ISWI and CHD1 chromatin remodelling activities influence ADH2 expression and chromatin organization.

Q5YDB6	CPL1_ARATH	RNA polymerase II C-terminal domain phosphatase-like 1	12149434	C-terminal domain phosphatase-like family members (AtCPLs) differentially regulate Arabidopsis thaliana abiotic stress signaling, growth, and development.

Q941C7	PSY1_ARATH	Protein PSY1	17989228	Tyrosine-sulfated glycopeptide involved in cellular proliferation and expansion in Arabidopsis.

Q9LG86	IAA2_ORYSJ	Auxin-responsive protein IAA2	16200395	Structure and expression analysis of early auxin-responsive Aux/IAA gene family in rice (Oryza sativa).

P38630	RFC1_YEAST	Replication factor C subunit 1	12665596	Mechanical link between cohesion establishment and DNA replication: Ctf7p/Eco1p, a cohesion establishment factor, associates with three different replication factor C complexes.

P0AGC3	SLT_ECOLI	Soluble lytic murein transglycosylase	1938883	Murein-metabolizing enzymes from Escherichia coli: sequence analysis and controlled overexpression of the slt gene, which encodes the soluble lytic transglycosylase.

P0ABM1	CCMC_ECOLI	Heme exporter protein C	7635817	Escherichia coli genes required for cytochrome c maturation.

Q08945	SSRP1_HUMAN	FACT complex subunit SSRP1	1372440	Isolation and characterization of human cDNA clones encoding a high mobility group box protein that recognizes structural distortions to DNA caused by binding of the anticancer agent cisplatin.

Q9BQ31	KCNS3_HUMAN	Potassium voltage-gated channel subfamily S member 3	10484328	Electrically silent potassium channel subunits from human lens epithelium.

Q96FV9	THOC1_HUMAN	THO complex subunit 1	15870275	Human hHpr1/p84/Thoc1 regulates transcriptional elongation and physically links RNA polymerase II and RNA processing factors.

Q9Y653	GPR56_HUMAN	G-protein coupled receptor 56	15044805	G protein-coupled receptor-dependent development of human frontal cortex.

Q08924	YP183_YEAST	Uncharacterized WD repeat-containing protein YPL183C	14562095	Global analysis of protein localization in budding yeast.

O43657	TSN6_HUMAN	Tetraspanin-6	12761501	Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.

Q02336	ADA2_YEAST	Transcriptional adapter 2	9674426	A subset of TAF(II)s are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulation.

Q86UN3	R4RL2_HUMAN	Reticulon-4 receptor-like 2	12694398	Characterization of two novel proteins, NgRH1 and NgRH2, structurally and biochemically homologous to the Nogo-66 receptor.

P81923	OR59A_DROME	Odorant receptor 59a	10089887	A spatial map of olfactory receptor expression in the Drosophila antenna.

P08575	PTPRC_HUMAN	Receptor-type tyrosine-protein phosphatase C	11909961	SKAP55 coupled with CD45 positively regulates T-cell receptor- mediated gene transcription.

O59722	FAB1_SCHPO	1-phosphatidylinositol-3-phosphate 5-kinase fab1	11895483	Phosphatidylinositol 3-phosphate 5-kinase is required for the cellular response to nutritional starvation and mating pheromone signals in Schizosaccharomyces pombe.

O00178	GTPB1_HUMAN	GTP-binding protein 1	9070279	Identification of human and mouse GP-1, a putative member of a novel G-protein family.

Q05942	RSA3_YEAST	Ribosome assembly protein 3	14562095	Global analysis of protein localization in budding yeast.

P40589	WNT4_DROME	Protein Wnt-4	11970894	DWnt4 regulates cell movement and focal adhesion kinase during Drosophila ovarian morphogenesis.

Q9UTR6	OCH1_SCHPO	Initiation-specific alpha-1,6-mannosyltransferase	11231017	Schizosaccharomyces pombe och1(+) encodes alpha-1,6- mannosyltransferase that is involved in outer chain elongation of N- linked oligosaccharides.

Q91989	P5F13_XENLA	POU domain, class 5, transcription factor 1.3	7582913	Xenopus interspersed RNA families, Ocr and XR, bind DNA-binding proteins.

Q9XI00	SKI32_ARATH	F-box protein 7	12795696	Protein interaction analysis of SCF ubiquitin E3 ligase subunits from Arabidopsis.

Q86KZ5	SBDS_DICDI	Ribosome maturation protein SBDS	16410554	The Shwachman-Bodian-Diamond syndrome gene encodes an RNA-binding protein that localizes to the pseudopod of Dictyostelium amoebae during chemotaxis.

Q9URU9	FYV10_SCHPO	Protein fyv10	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O42606	NGN1_DANRE	Neurogenin-1	12413897	Neurogenin1 defines zebrafish cranial sensory ganglia precursors.

O74944	POLK_SCHPO	DNA polymerase kappa	12514100	Checkpoint activation regulates mutagenic translesion synthesis.

Q92356	SYB1_SCHPO	Synaptobrevin homolog 1	12565827	Fission yeast synaptobrevin is involved in cytokinesis and cell elongation.

Q54GP8	GLRX_DICDI	Glutaredoxin	16678813	Reduced glutathione levels affect the culmination and cell fate decision in Dictyostelium discoideum.

Q8LAH7	OPR1_ARATH	12-oxophytodienoate reductase 1	10333582	Structure and regulation of OPR1 and OPR2, two closely related genes encoding 12-oxophytodienoic acid-10,11-reductases from Arabidopsis thaliana.

P43554	SWP82_YEAST	SWI/SNF global transcription activator complex subunit SWP82	14562095	Global analysis of protein localization in budding yeast.

O94682	YG7G_SCHPO	Uncharacterized protein C776.16	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O14920	IKKB_HUMAN	Inhibitor of nuclear factor kappa-B kinase subunit beta	16177806	Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus.

P43589	SAD1_YEAST	Pre-mRNA-splicing factor SAD1	10022888	A novel genetic screen for snRNP assembly factors in yeast identifies a conserved protein, Sad1p, also required for pre-mRNA splicing.

P19493	GRIA4_RAT	Glutamate receptor 4	1699275	Flip and flop: a cell-specific functional switch in glutamate- operated channels of the CNS.

P39105	PLB1_YEAST	Lysophospholipase 1	8051052	The Saccharomyces cerevisiae PLB1 gene encodes a protein required for lysophospholipase and phospholipase B activity.

Q08211	DHX9_HUMAN	ATP-dependent RNA helicase A	19029303	Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs.

Q9PT61	OTX5B_XENLA	Homeobox protein otx5-B	10940620	Xotx5b, a new member of the Otx gene family, may be involved in anterior and eye development in Xenopus laevis.

Q6Z1Z3	IDEF1_ORYSJ	B3 domain-containing protein IDEF1	18025467	The transcription factor IDEF1 regulates the response to and tolerance of iron deficiency in plants.

Q94A94	DCDA2_ARATH	Diaminopimelate decarboxylase 2, chloroplastic	15652176	Biosynthesis of lysine in plants: evidence for a variant of the known bacterial pathways.

Q07794	RT109_YEAST	Histone acetyltransferase RTT109	14562095	Global analysis of protein localization in budding yeast.

Q9BYV2	TRI54_HUMAN	Tripartite motif-containing protein 54	11243782	Identification of muscle specific ring finger proteins as potential regulators of the titin kinase domain.

P37671	YIAJ_ECOLI	HTH-type transcriptional regulator yiaJ	10913096	Regulation of expression of the yiaKLMNOPQRS operon for carbohydrate utilization in Escherichia coli: involvement of the main transcriptional factors.

Q9Z0G9	CLD3_MOUSE	Claudin-3	9892664	Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands.

Q9C7B1	TRP3_ARATH	Telomere repeat-binding protein 3	15688221	AtTBP2 and AtTRP2 in Arabidopsis encode proteins that bind plant telomeric DNA and induce DNA bending in vitro.

Q9U1S7	PKD2_CAEEL	Polycystin-2	16943275	General and cell-type specific mechanisms target TRPP2/PKD-2 to cilia.

Q96524	CRY2_ARATH	Cryptochrome-2	11509693	Direct interaction of Arabidopsis cryptochromes with COP1 in light control development.

P47871	GLR_HUMAN	Glucagon receptor	8144028	The human glucagon receptor encoding gene: structure, cDNA sequence and chromosomal localization.

Q61469	LPP1_MOUSE	Lipid phosphate phosphohydrolase 1	8702556	Identification and cDNA cloning of 35-kDa phosphatidic acid phosphatase (type 2) bound to plasma membranes.

P32121	ARRB2_HUMAN	Beta-arrestin-2	15878855	{beta}-Arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth factor-1 receptor by acting as adaptor for the MDM2 E3 ligase.

P53323	BUD32_YEAST	Serine/threonine-protein kinase BUD32	11452010	A genomic study of the bipolar bud site selection pattern in Saccharomyces cerevisiae.

Q05934	VID22_YEAST	Vacuolar import and degradation protein 22	11861771	Vid22p, a novel plasma membrane protein, is required for the fructose-1,6-bisphosphatase degradation pathway.

O96042	DIA2_DICDI	Differentiation-associated protein 2	17825085	Involvements of a novel protein, DIA2, in cAMP signaling and spore differentiation during Dictyostelium development.

P40897	OPT1_YEAST	Oligopeptide transporter 1	10788431	Hgt1p, a high affinity glutathione transporter from the yeast Saccharomyces cerevisiae.

Q8BMF4	ODP2_MOUSE	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial	12108679	Molecular cloning, and characterization and expression of dihydrolipoamide acetyltransferase component of murine pyruvate dehydrogenase complex in bile duct cancer cells.

P38356	BSD2_YEAST	Metal homeostatis protein BSD2	9115231	Negative control of heavy metal uptake by the Saccharomyces cerevisiae BSD2 gene.

O60341	KDM1A_HUMAN	Lysine-specific histone demethylase 1A	16079795	LSD1 demethylates repressive histone marks to promote androgen- receptor-dependent transcription.

Q8LFC0	IDH1_ARATH	Isocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

O13516	RS9A_YEAST	40S ribosomal protein S9-A	6814480	Isolation of seventeen proteins and amino-terminal amino acid sequences of eight proteins from cytoplasmic ribosomes of yeast.

P20226	TBP_HUMAN	TATA-box-binding protein	12217962	Functional substitution for TAF(II)250 by a retroposed homolog that is expressed in human spermatogenesis.

P67936	TPM4_HUMAN	Tropomyosin alpha-4 chain	1836432	The calcium binding protein tropomyosin in human platelets and cardiac tissue: elevation in hypertensive cardiac hypertrophy.

P78423	X3CL1_HUMAN	Fractalkine	9931005	Solution structure and dynamics of the CX3C chemokine domain of fractalkine and its interaction with an N-terminal fragment of CX3CR1.

P25342	CDC10_YEAST	Cell division control protein 10	9813094	Polymerization of purified yeast septins: evidence that organized filament arrays may not be required for septin function.

Q8LB02	DHSB2_ARATH	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit 2, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P33304	AFR1_YEAST	Protein AFR1	8413281	AFR1 acts in conjunction with the alpha-factor receptor to promote morphogenesis and adaptation.

Q9R1K7	TBD_MOUSE	Tubulin delta chain	10753753	Tissue-specific expression and subcellular localisation of mammalian delta-tubulin.

P48439	OST3_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3	10358084	The oligosaccharyltransferase complex from Saccharomyces cerevisiae. Isolation of the OST6 gene, its synthetic interaction with OST3, and analysis of the native complex.

Q9D666	SUN1_MOUSE	SUN domain-containing protein 1	16380439	Coupling of the nucleus and cytoplasm: role of the LINC complex.

Q06679	UTP4_YEAST	U3 small nucleolar RNA-associated protein 4	12068309	A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis.

P84792	HBB_AYTFU	Hemoglobin subunit beta	11829480	Molecular basis of bird respiration: primary hemoglobin structure component from Tufted duck (Aythya fuligula, Anseriformes)-role of alpha99Arg in formation of a complex salt bridge network.

P25100	ADA1D_HUMAN	Alpha-1D adrenergic receptor	7746284	Cloning of the human alpha 1d-adrenergic receptor and inducible expression of three human subtypes in SK-N-MC cells.

P35222	CTNB1_HUMAN	Catenin beta-1	10192393	A common human skin tumour is caused by activating mutations in beta- catenin.

O42666	BUT1_SCHPO	Uba3-binding protein but1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P52920	NBP35_YEAST	Cytosolic Fe-S cluster assembly factor NBP35	17401378	The Cfd1-Nbp35 complex acts as a scaffold for iron-sulfur protein assembly in the yeast cytosol.

P30664	MCM4B_XENLA	DNA replication licensing factor mcm4-B	8605878	Chromotin binding, nuclear localization and phosphorylation of Xenopus cdc21 are cell-cycle dependent and associated with the control of initiation of DNA replication.

Q8LBW3	LBD12_ARATH	LOB domain-containing protein 12	12040093	The ASYMMETRIC LEAVES2 gene of Arabidopsis thaliana, required for formation of a symmetric flat leaf lamina, encodes a member of a novel family of proteins characterized by cysteine repeats and a leucine zipper.

P39524	ATC3_YEAST	Probable phospholipid-transporting ATPase DRS2	15090616	Cdc50p, a protein required for polarized growth, associates with the Drs2p P-type ATPase implicated in phospholipid translocation in Saccharomyces cerevisiae.

Q9UST1	PAN3_SCHPO	PAB-dependent poly(A)-specific ribonuclease subunit pan3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q04756	HGFA_HUMAN	Hepatocyte growth factor activator	15713485	Conformational lability in serine protease active sites: structures of hepatocyte growth factor activator (HGFA) alone and with the inhibitory domain from HGFA inhibitor-1B.

P0A6X1	HEM1_ECOLI	Glutamyl-tRNA reductase	2548996	Isolation, nucleotide sequence, and preliminary characterization of the Escherichia coli K-12 hemA gene.

O75665	OFD1_HUMAN	Oral-facial-digital syndrome 1 protein	20230748	Ofd1, a human disease gene, regulates the length and distal structure of centrioles.

Q9VC44	ALLS_DROME	Allatostatins Ast	10891383	Molecular cloning and genomic organization of an Allatostatin preprohormone from Drosophila melanogaster.

Q46806	PHYDA_ECOLI	D-phenylhydantoinase	11092864	Functional expression and characterization of the two cyclic amidohydrolase enzymes, allantoinase and a novel phenylhydantoinase, from Escherichia coli.

P49327	FAS_HUMAN	Fatty acid synthase	18022563	Mechanism and substrate recognition of human holo ACP synthase.

Q06665	RAD34_YEAST	DNA repair protein RAD34	15916602	The Rad4 homologue YDR314C is essential for strand-specific repair of RNA polymerase I-transcribed rDNA in Saccharomyces cerevisiae.

P63166	SUMO1_MOUSE	Small ubiquitin-related modifier 1	15225651	Increase of SUMO-1 expression in response to hypoxia: direct interaction with HIF-1alpha in adult mouse brain and heart in vivo.

P40018	RSMB_YEAST	Small nuclear ribonucleoprotein-associated protein B	9630245	A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins.

P0A6F5	CH60_ECOLI	60 kDa chaperonin	9285585	The crystal structure of the asymmetric GroEL-GroES-(ADP)7 chaperonin complex.

Q558U1	IFKA_DICDI	Probable serine/threonine-protein kinase ifkA	12697064	IfkA, a presumptive eIF2 alpha kinase of Dictyostelium, is required for proper timing of aggregation and regulation of mound size.

Q9JLU4	SHAN3_RAT	SH3 and multiple ankyrin repeat domains protein 3	15014124	Linkage of the actin cytoskeleton to the postsynaptic density via direct interactions of Abp1 with the ProSAP/Shank family.

P04910	H2A2_SCHPO	Histone H2A-beta	15226425	Histone H2A phosphorylation controls Crb2 recruitment at DNA breaks, maintains checkpoint arrest, and influences DNA repair in fission yeast.

P43124	NSE4_YEAST	Non-structural maintenance of chromosome element 4	15738391	A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization.

P83010	13KDA_TRISC	13 kDa protein	11676495	N-terminal sequences of small ion channels in rectal glands of sharks: a biochemical hallmark for classification and phylogeny?

Q9C1W9	DNLI3_SCHPO	DNA ligase 3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q94361	GEI17_CAEEL	E3 SUMO-protein ligase gei-17	15654100	Systematic, RNA-interference-mediated identification of mus-101 modifier genes in Caenorhabditis elegans.

Q9NF14	BAT40_CAEEL	BTB and MATH domain-containing protein 40	13679922	BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3.

P32368	SAC1_YEAST	Phosphoinositide phosphatase SAC1	20182505	Orm family proteins mediate sphingolipid homeostasis.

Q60954	MEIS1_MOUSE	Homeobox protein Meis1	12183364	Meis homeoproteins directly regulate Pax6 during vertebrate lens morphogenesis.

P38936	CDN1A_HUMAN	Cyclin-dependent kinase inhibitor 1	18794347	PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex.

P39970	ACA1_YEAST	ATF/CREB activator 1	10825197	Aca1 and Aca2, ATF/CREB activators in Saccharomyces cerevisiae, are important for carbon source utilization but not the response to stress.

Q96T37	RBM15_HUMAN	Putative RNA-binding protein 15	16129689	Interaction of the Epstein-Barr virus mRNA export factor EB2 with human Spen proteins SHARP, OTT1, and a novel member of the family, OTT3, links Spen proteins with splicing regulation and mRNA export.

P36102	PAN3_YEAST	PAB-dependent poly(A)-specific ribonuclease subunit PAN3	8816488	PAN3 encodes a subunit of the Pab1p-dependent poly(A) nuclease in Saccharomyces cerevisiae.

Q38851	MYB6_ARATH	Transcription repressor MYB6	16463103	The MYB transcription factor superfamily of Arabidopsis: expression analysis and phylogenetic comparison with the rice MYB family.

Q09472	EP300_HUMAN	Histone acetyltransferase p300	8684459	A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A.

O01395	MST3_DROHY	Axoneme-associated protein mst101(3)	10445506	Proteins with tandemly arranged repeats of a highly charged 16-amino- acid motif encoded by the Dhmst101 gene family are structural components of the outer sheath of the extremely elongated sperm tails of Drosophila hydei.

Q08775	RUNX2_MOUSE	Runt-related transcription factor 2	16751105	SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation.

Q62611	ILRL1_RAT	Interleukin-1 receptor-like 1	8131748	Alternative promoter usage of the Fos-responsive gene Fit-1 generates mRNA isoforms coding for either secreted or membrane-bound proteins related to the IL-1 receptor.

Q8TDR0	MIPT3_HUMAN	TRAF3-interacting protein 1	12812986	DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation.

Q0WUI9	TPS8_ARATH	Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 8	11520870	Trehalose metabolism in Arabidopsis: occurrence of trehalose and molecular cloning and characterization of trehalose-6-phosphate synthase homologues.

Q14152	EIF3A_HUMAN	Eukaryotic translation initiation factor 3 subunit A	11169732	Molecular interaction between human tumor marker protein p150, the largest subunit of eIF3, and intermediate filament protein K7.

P40015	ISC1_YEAST	Inositol phosphosphingolipids phospholipase C	11006294	Identification of ISC1 (YER019w) as inositol phosphosphingolipid phospholipase C in Saccharomyces cerevisiae.

O81055	ASK16_ARATH	SKP1-like protein 16	19682297	An F-box gene, CPR30, functions as a negative regulator of the defense response in Arabidopsis.

O95628	CNOT4_HUMAN	CCR4-NOT transcription complex subunit 4	15001359	An altered-specificity ubiquitin-conjugating enzyme/ubiquitin-protein ligase pair.

Q18973	GSTK2_CAEEL	Glutathione s-transferase kappa 2	19663909	Glutathione transferases kappa 1 and kappa 2 localize in peroxisomes and mitochondria, respectively, and are involved in lipid metabolism and respiration in Caenorhabditis elegans.

O74796	ORC6_SCHPO	Origin recognition complex subunit 6	11850415	Purification and characterization of the Schizosaccharomyces pombe origin recognition complex: interaction with origin DNA and Cdc18 protein.

O75078	ADA11_HUMAN	Disintegrin and metalloproteinase domain-containing protein 11	8252040	A novel metalloprotease/disintegrin-like gene at 17q21.3 is somatically rearranged in two primary breast cancers.

Q9NZD4	AHSP_HUMAN	Alpha-hemoglobin-stabilizing protein	15550245	Molecular mechanism of AHSP-mediated stabilization of alpha- hemoglobin.

Q0WP12	HOL1_ARATH	Thiocyanate methyltransferase 1	19419967	Arabidopsis HARMLESS TO OZONE LAYER protein methylates a glucosinolate breakdown product and functions in resistance to Pseudomonas syringae pv. maculicola.

Q9FIA0	CNGT2_ARATH	Cytokinin-N-glucosyltransferase 2	15342621	N-glucosylation of cytokinins by glycosyltransferases of Arabidopsis thaliana.

Q96EB6	SIRT1_HUMAN	NAD-dependent deacetylase sirtuin-1	10381378	Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity.

O22059	CPC_ARATH	Transcription factor CPC	14627722	The bHLH genes GLABRA3 (GL3) and ENHANCER OF GLABRA3 (EGL3) specify epidermal cell fate in the Arabidopsis root.

Q9KNX6	SLYD_VIBCH	FKBP-type peptidyl-prolyl cis-trans isomerase slyD	16388577	SlyD proteins from different species exhibit high prolyl isomerase and chaperone activities.

P53131	PRP43_YEAST	Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43	16357217	Spliceosome disassembly catalyzed by Prp43 and its associated components Ntr1 and Ntr2.

P18136	KV313_HUMAN	Ig kappa chain V-III region HIC	3127527	Autoantibody-associated kappa light chain variable region gene expressed in chronic lymphocytic leukemia with little or no somatic mutation. Implications for etiology and immunotherapy.

Q9FVI6	FWA_ARATH	Homeobox-leucine zipper protein HDG6	17189287	Molecular basis of late-flowering phenotype caused by dominant epi- alleles of the FWA locus in Arabidopsis.

P08723	SPBP_RAT	Prostatic spermine-binding protein	3818623	Prostatic spermine-binding protein. Cloning and nucleotide sequence of cDNA, amino acid sequence, and androgenic control of mRNA level.

Q63678	ZA2G_RAT	Zinc-alpha-2-glycoprotein	8056339	Cloning and expression analysis of the cDNA encoding rat Zn-alpha 2- glycoprotein.

P42768	WASP_HUMAN	Wiskott-Aldrich syndrome protein	8069912	Isolation of a novel gene mutated in Wiskott-Aldrich syndrome.

P87295	PEP5L_SCHPO	Pep5-like zinc finger protein C16A10.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O59774	YPS1_SCHPO	Aspartic proteinase yapsin-1	11115118	Identification of proteases with shared functions to the proprotein processing protease Krp1 in the fission yeast Schizosaccharomyces pombe.

Q9FUY7	C79F2_ARATH	Hexahomomethionine N-hydroxylase	11226190	Bus, a bushy Arabidopsis CYP79F1 knockout mutant with abolished synthesis of short-chain aliphatic glucosinolates.

O02002	CASP1_DROME	Caspase-1	8999799	DCP-1, a Drosophila cell death protease essential for development.

P54867	SLG1_YEAST	Protein SLG1	10430578	Characterization of the Wsc1 protein, a putative receptor in the stress response of Saccharomyces cerevisiae.

O74325	YH05_SCHPO	PDZ domain-containing protein C1685.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q96IZ0	PAWR_HUMAN	PRKC apoptosis WT1 regulator protein	15671026	PAR-4 is involved in regulation of beta-secretase cleavage of the Alzheimer amyloid precursor protein.

O13658	YBCB_SCHPO	Uncharacterized transcriptional regulatory protein C27B12.11c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q20065	P4HA2_CAEEL	Prolyl 4-hydroxylase subunit alpha-2	12036960	The exoskeleton collagens in Caenorhabditis elegans are modified by prolyl 4-hydroxylases with unique combinations of subunits.

Q05031	DFG5_YEAST	Mannan endo-1,6-alpha-mannosidase DFG5	12421307	Two homologous genes, DCW1 (YKL046c) and DFG5, are essential for cell growth and encode glycosylphosphatidylinositol (GPI)-anchored membrane proteins required for cell wall biogenesis in Saccharomyces cerevisiae.

O00443	P3C2A_HUMAN	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit alpha	9337861	Cloning of a human phosphoinositide 3-kinase with a C2 domain which displays reduced sensitivity to the inhibitor wortmannin.

Q8VHN2	NMD3B_RAT	Glutamate [NMDA] receptor subunit 3B	11823786	Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits.

P41252	SYIC_HUMAN	Isoleucyl-tRNA synthetase, cytoplasmic	7721108	Human isoleucyl-tRNA synthetase: sequence of the cDNA, alternative mRNA splicing, and the characteristics of an unusually long C-terminal extension.

Q9U405	GRAU_DROME	Transcription factor grauzone	10683177	Completion of meiosis in Drosophila oocytes requires transcriptional control by grauzone, a new zinc finger protein.

P78963	SKB1_SCHPO	Protein arginine N-methyltransferase skb1	8943016	The highly conserved skb1 gene encodes a protein that interacts with Shk1, a fission yeast Ste20/PAK homolog.

P42679	MATK_HUMAN	Megakaryocyte-associated tyrosine-protein kinase	7530249	Structural and functional studies of the intracellular tyrosine kinase MATK gene and its translated product.

O95292	VAPB_HUMAN	Vesicle-associated membrane protein-associated protein B/C	16227268	Human VAP-B is involved in hepatitis C virus replication through interaction with NS5A and NS5B.

P31750	AKT1_MOUSE	RAC-alpha serine/threonine-protein kinase	9415393	Physiological role of Akt in insulin-stimulated translocation of GLUT4 in transfected rat adipose cells.

Q9P7J4	YJNB_SCHPO	Uncharacterized protein SPCC24B10.11c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P55809	SCOT1_HUMAN	Succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial	9671268	Succinyl-CoA:3-ketoacid CoA transferase (SCOT) deficiency: two pathogenic mutations, V133E and C456F, in Japanese siblings.

O35738	KLF12_MOUSE	Krueppel-like factor 12	9858544	Transcriptional regulation of the AP-2alpha promoter by BTEB-1 and AP-2rep, a novel wt-1/egr-related zinc finger repressor.

Q9WTV0	PREB_RAT	Prolactin regulatory element-binding protein	10194769	Expression cloning and characterization of PREB (prolactin regulatory element binding), a novel WD motif DNA-binding protein with a capacity to regulate prolactin promoter activity.

Q9H2S9	IKZF4_HUMAN	Zinc finger protein Eos	10978333	Eos and pegasus, two members of the Ikaros family of proteins with distinct DNA binding activities.

Q9LP46	SCAR3_ARATH	Protein SCAR3	17267444	The role of Arabidopsis SCAR genes in ARP2-ARP3-dependent cell morphogenesis.

Q62962	ACCN1_RAT	Amiloride-sensitive cation channel 1, neuronal	14976185	ASIC2b-dependent regulation of ASIC3, an essential acid-sensing ion channel subunit in sensory neurons via the partner protein PICK-1.

Q38825	IAA7_ARATH	Auxin-responsive protein IAA7	12036262	Genetics of Aux/IAA and ARF action in plant growth and development.

O60161	UTP4_SCHPO	U3 small nucleolar RNA-associated protein 4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P58751	RELN_RAT	Reelin	12670697	Rat neurological disease creeping is caused by a mutation in the reelin gene.

Q9VPT1	GR21A_DROME	Gustatory and odorant receptor 21a	10710312	Candidate taste receptors in Drosophila.

Q12495	RLF2_YEAST	Chromatin assembly factor 1 subunit p90	9030687	Ultraviolet radiation sensitivity and reduction of telomeric silencing in Saccharomyces cerevisiae cells lacking chromatin assembly factor-I.

P34611	NCL1_CAEEL	B-box type zinc finger protein ncl-1	9508766	Ncl-1 is required for the regulation of cell size and ribosomal RNA synthesis in Caenorhabditis elegans.

P02692	FABPL_RAT	Fatty acid-binding protein, liver	1939124	Identification by photoaffinity labeling of fatty acid-binding protein as a potential warfarin receptor in rat liver.

P52737	ZN136_HUMAN	Zinc finger protein 136	7649249	Repression of transcriptional activity by heterologous KRAB domains present in zinc finger proteins.

Q54HG2	CTXA_DICDI	Cortexillin-1	18039932	Regulation of Rap1 activity by RapGAP1 controls cell adhesion at the front of chemotaxing cells.

Q24049	AMN_DROME	Amnesiac neuropeptides	11517334	Control of Drosophila perineurial glial growth by interacting neurotransmitter-mediated signaling pathways.

Q5S248	TM11E_MOUSE	Transmembrane protease serine 11E	15328353	Mouse DESC1 is located within a cluster of seven DESC1-like genes and encodes a type II transmembrane serine protease that forms serpin inhibitory complexes.

P58905	AMT11_SOLLC	Ammonium transporter 1 member 1	10743657	Differential regulation of three functional ammonium transporter genes by nitrogen in root hairs and by light in leaves of tomato.

Q80UQ2	RASF6_MOUSE	Ras association domain-containing protein 6	17404571	RASSF6 is a novel member of the RASSF family of tumor suppressors.

Q9UM21	MGT4A_HUMAN	Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A	10024668	Tissue specific expression and chromosomal mapping of a human UDP-N- acetylglucosamine: alpha1,3-d-mannoside beta1, 4-N- acetylglucosaminyltransferase.

O60169	YHC5_SCHPO	Uncharacterized protein C19F8.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q94K73	SYFM_ARATH	Phenylalanyl-tRNA synthetase, chloroplastic/mitochondrial	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q9FKS4	ATR_ARATH	Serine/threonine-protein kinase ATR	16166376	ATM and ATR make distinct contributions to chromosome end protection and the maintenance of telomeric DNA in Arabidopsis.

P49279	NRAM1_HUMAN	Natural resistance-associated macrophage protein 1	7717395	Identification of polymorphisms and sequence variants in the human homologue of the mouse natural resistance-associated macrophage protein gene.

P53632	PAP2_YEAST	Poly(A) RNA polymerase protein 2	15935758	RNA degradation by the exosome is promoted by a nuclear polyadenylation complex.

Q9Y4Z0	LSM4_HUMAN	U6 snRNA-associated Sm-like protein LSm4	10369684	Sm and Sm-like proteins assemble in two related complexes of deep evolutionary origin.

Q8K339	KIN17_MOUSE	DNA/RNA-binding protein KIN17	1923796	Identification and expression of the cDNA of KIN17, a zinc-finger gene located on mouse chromosome 2, encoding a new DNA-binding protein.

P62633	CNBP_HUMAN	Cellular nucleic acid-binding protein	2562787	Identification of a zinc finger protein that binds to the sterol regulatory element.

Q06518	NOS2_RAT	Nitric oxide synthase, inducible	9851365	Complete coding sequence of inducible nitric oxide synthase from human heart and skeletal muscle of patients with chronic heart failure.

P11532	DMD_HUMAN	Dystrophin	3282674	The complete sequence of dystrophin predicts a rod-shaped cytoskeletal protein.

P36029	TPO5_YEAST	Polyamine transporter TPO5	15668236	Excretion of putrescine and spermidine by the protein encoded by YKL174c (TPO5) in Saccharomyces cerevisiae.

P13607	ATNA_DROME	Sodium/potassium-transporting ATPase subunit alpha	9648860	Functional analysis and tissue-specific expression of Drosophila Na+,K+-ATPase subunits.

Q02297	NRG1_HUMAN	Pro-neuregulin-1, membrane-bound isoform	8096067	Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system.

P51521	OVO_DROME	Protein ovo	12915226	The Ovo/Shavenbaby transcription factor specifies actin remodelling during epidermal differentiation in Drosophila.

Q9M9L7	LONM4_ARATH	Lon protease homolog 4, chloroplastic/mitochondrial	17478548	Multiple intracellular locations of Lon protease in Arabidopsis: evidence for the localization of AtLon4 to chloroplasts.

A2ARP9	CTSR2_MOUSE	Cation channel sperm-associated protein 2	17174296	Contributions of extracellular and intracellular Ca2+ to regulation of sperm motility: release of intracellular stores can hyperactivate CatSper1 and CatSper2 null sperm.

P25358	ELO2_YEAST	Elongation of fatty acids protein 2	9211877	ELO2 and ELO3, homologues of the Saccharomyces cerevisiae ELO1 gene, function in fatty acid elongation and are required for sphingolipid formation.

Q14993	COJA1_HUMAN	Collagen alpha-1(XIX) chain	7775380	The mRNA for alpha 1(XIX) collagen chain, a new member of FACITs, contains a long unusual 3' untranslated region and displays many unique splicing variants.

O14957	QCR10_HUMAN	Cytochrome b-c1 complex subunit 10	9161705	Primary structure of the smallest (6.4-kDa) subunit of human and bovine ubiquinol-cytochrome c reductase deduced from cDNA sequences.

P53083	MDM34_YEAST	Mitochondrial distribution and morphology protein 34	19556461	An ER-mitochondria tethering complex revealed by a synthetic biology screen.

Q9S7I3	NLTP2_ARATH	Non-specific lipid-transfer protein 2	18050905	Identification of novel mitochondrial membrane protein (Cdf 3) from Arabidopsis thaliana and its functional analysis in a yeast system.

O14713	ITBP1_HUMAN	Integrin beta-1-binding protein 1	9281591	ICAP-1, a novel beta1 integrin cytoplasmic domain-associated protein, binds to a conserved and functionally important NPXY sequence motif of beta1 integrin.

P51682	CCR5_MOUSE	C-C chemokine receptor type 5	8631787	Molecular cloning and functional expression of murine JE (monocyte chemoattractant protein 1) and murine macrophage inflammatory protein 1alpha receptors: evidence for two closely linked C-C chemokine receptors on chromosome 9.

P21507	SRMB_ECOLI	ATP-dependent RNA helicase srmB	15196029	Studies on three E. coli DEAD-box helicases point to an unwinding mechanism different from that of model DNA helicases.

Q9UPQ8	DOLK_HUMAN	Dolichol kinase	12213788	Expression and characterization of a human cDNA that complements the temperature-sensitive defect in dolichol kinase activity in the yeast sec59-1 mutant: the enzymatic phosphorylation of dolichol and diacylglycerol are catalyzed by separate CTP-mediated kinase activities in Saccharomyces cerevisiae.

Q0WML0	AB27B_ARATH	ABC transporter B family member 27	17171374	Arabidopsis ALS1 encodes a root tip and stele localized half type ABC transporter required for root growth in an aluminum toxic environment.

O75387	LAT3_HUMAN	Large neutral amino acids transporter small subunit 3	12930836	Identification of a novel system L amino acid transporter structurally distinct from heterodimeric amino acid transporters.

O94462	PUF3_SCHPO	mRNA-binding protein puf3	12529438	Global transcriptional responses of fission yeast to environmental stress.

P42867	GPT_MOUSE	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	1323278	Mouse UDP-GlcNAc: dolichyl-phosphate N- acetylglucosaminephosphotransferase. Molecular cloning of the cDNA, generation of anti-peptide antibodies and chromosomal localization.

Q76LW6	DAND5_MOUSE	DAN domain family member 5	15466485	The activity of the Nodal antagonist Cerl-2 in the mouse node is required for correct L/R body axis.

P47752	S1PR2_RAT	Sphingosine 1-phosphate receptor 2	9409733	Identification of cDNAs encoding two G protein-coupled receptors for lysosphingolipids.

P01123	YPT1_YEAST	GTP-binding protein YPT1	9447979	GTP hydrolysis is not important for Ypt1 GTPase function in vesicular transport.

Q01415	GALK2_HUMAN	N-acetylgalactosamine kinase	8798585	Identification of the GalNAc kinase amino acid sequence.

P78599	DCOR_CANAL	Ornithine decarboxylase	9392083	Isolation and sequence of the gene encoding ornithine decarboxylase, SPE1, from Candida albicans by complementation of a spe1 delta strain of Saccharomyces cerevisiae.

P14618	KPYM_HUMAN	Pyruvate kinase isozymes M1/M2	2813362	Cytosolic thyroid hormone-binding protein is a monomer of pyruvate kinase.

Q9Z0S9	PRAF1_MOUSE	Prenylated Rab acceptor protein 1	10964695	Mouse prenylated Rab acceptor is a novel Golgi membrane protein.

P46736	BRCC3_HUMAN	Lys-63-specific deubiquitinase BRCC36	14636569	Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair.

Q8GXA4	WIP1_ARATH	WPP domain-interacting protein 1	18591351	Two distinct interacting classes of nuclear envelope-associated coiled-coil proteins are required for the tissue-specific nuclear envelope targeting of Arabidopsis RanGAP.

Q9US15	YK62_SCHPO	UPF0653 protein C607.02c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P23435	CBLN1_HUMAN	Cerebellin-1	1704129	Precerebellin is a cerebellum-specific protein with similarity to the globular domain of complement C1q B chain.

Q99J45	NRBP_MOUSE	Nuclear receptor-binding protein	12176995	MADM, a novel adaptor protein that mediates phosphorylation of the 14-3-3 binding site of myeloid leukemia factor 1.

Q8W1X2	PDXK_ARATH	Pyridoxal kinase	11910005	The Arabidopsis salt overly sensitive 4 mutants uncover a critical role for vitamin B6 in plant salt tolerance.

P50613	CDK7_HUMAN	Cell division protein kinase 7	7936635	Cloning, expression and subcellular localization of the human homolog of p40MO15 catalytic subunit of cdk-activating kinase.

Q13177	PAK2_HUMAN	Serine/threonine-protein kinase PAK 2	18716323	Scrib regulates PAK activity during the cell migration process.

Q12874	SF3A3_HUMAN	Splicing factor 3A subunit 3	7816610	Splicing factor SF3a60 is the mammalian homologue of PRP9 of S.cerevisiae: the conserved zinc finger-like motif is functionally exchangeable in vivo.

Q9U1M8	MYOI_DICDI	Myosin-I heavy chain	17189480	The SH3 domain of a M7 interacts with its C-terminal proline-rich region.

Q9JII5	DAZP1_MOUSE	DAZ-associated protein 1	11604102	Characterization of the mouse Dazap1 gene encoding an RNA-binding protein that interacts with infertility factors DAZ and DAZL.

Q99608	NECD_HUMAN	Necdin	9630521	The human chromosomal gene for necdin, a neuronal growth suppressor, in the Prader-Willi syndrome deletion region.

Q13409	DC1I2_HUMAN	Cytoplasmic dynein 1 intermediate chain 2	8522607	Cytoplasmic dynein binds dynactin through a direct interaction between the intermediate chains and p150Glued.

O00755	WNT7A_HUMAN	Protein Wnt-7a	16826533	Mutations in WNT7A cause a range of limb malformations, including Fuhrmann syndrome and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndrome.

P53083	MDM34_YEAST	Mitochondrial distribution and morphology protein 34	16407407	Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins.

P76535	MURQ_ECOLI	N-acetylmuramic acid 6-phosphate etherase	18837509	Mechanistic studies on N-acetylmuramic acid 6-phosphate hydrolase (MurQ): an etherase involved in peptidoglycan recycling.

P46962	CTK2_YEAST	CTD kinase subunit beta	15520468	CTD kinase I is involved in RNA polymerase I transcription.

P27169	PON1_HUMAN	Serum paraoxonase/arylesterase 1	10479665	Human serum paraoxonase/arylesterase's retained hydrophobic N- terminal leader sequence associates with HDLs by binding phospholipids: apolipoprotein A-I stabilizes activity.

Q9D9T8	EFHC1_MOUSE	EF-hand domain-containing protein 1	15670853	The mouse ortholog of EFHC1 implicated in juvenile myoclonic epilepsy is an axonemal protein widely conserved among organisms with motile cilia and flagella.

O75400	PR40A_HUMAN	Pre-mRNA-processing factor 40 homolog A	16391387	Interaction of the nuclear matrix protein NAKAP with HypA and huntingtin: implications for nuclear toxicity in Huntington's disease pathogenesis.

Q9S850	SUOX_ARATH	Sulfite oxidase	11598126	Identification and biochemical characterization of Arabidopsis thaliana sulfite oxidase. A new player in plant sulfur metabolism.

O17386	CED8_CAEEL	Cell death abnormality protein 8	1936965	Genes required for the engulfment of cell corpses during programmed cell death in Caenorhabditis elegans.

Q14839	CHD4_HUMAN	Chromodomain-helicase-DNA-binding protein 4	19644445	ZIP: a novel transcription repressor, represses EGFR oncogene and suppresses breast carcinogenesis.

Q9ULW5	RAB26_HUMAN	Ras-related protein Rab-26	11043516	cDNA cloning of a human RAB26-related gene encoding a Ras-like GTP- binding protein on chromosome 16p13.3 region.

Q9EQ32	BCAP_MOUSE	Phosphoinositide 3-kinase adapter protein 1	11163197	BCAP: the tyrosine kinase substrate that connects B cell receptor to phosphoinositide 3-kinase activation.

P87236	MU154_SCHPO	Meiotically up-regulated gene 154 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q96FX2	DPH3_HUMAN	DPH3 homolog	14980502	Characterisation of an evolutionary conserved protein interacting with the putative guanine nucleotide exchange factor DelGEF and modulating secretion.

Q02720	CSK2A_DICDI	Casein kinase II subunit alpha	1448100	Molecular cloning of casein kinase II alpha subunit from Dictyostelium discoideum and its expression in the life cycle.

O60262	GBG7_HUMAN	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7	9600093	Identification and cloning of human G-protein gamma 7, down-regulated in pancreatic cancer.

P69428	TATA_ECOLI	Sec-independent protein translocase protein tatA	16027357	The TatA component of the twin-arginine protein transport system forms channel complexes of variable diameter.

P02810	PRPC_HUMAN	Salivary acidic proline-rich phosphoprotein 1/2	2993301	Differential RNA splicing and post-translational cleavages in the human salivary proline-rich protein gene system.

P55272	CDN2B_RAT	Cyclin-dependent kinase 4 inhibitor B	7546221	Molecular genetic basis of renal carcinogenesis in the Eker rat model of tuberous sclerosis (Tsc2).

P18846	ATF1_HUMAN	Cyclic AMP-dependent transcription factor ATF-1	2196176	Multiple cDNA clones encoding nuclear proteins that bind to the tax- dependent enhancer of HTLV-1: all contain a leucine zipper structure and basic amino acid domain.

P52166	PSN_CAEEL	Presenilin sel-12	10917532	Presenilin is required for proper morphology and function of neurons in C. elegans.

P48637	GSHB_HUMAN	Glutathione synthetase	8896573	Mutations in the glutathione synthetase gene cause 5-oxoprolinuria.

P55085	PAR2_HUMAN	Proteinase-activated receptor 2	7556175	Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2.

O15511	ARPC5_HUMAN	Actin-related protein 2/3 complex subunit 5	9230079	The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly.

Q945F0	EDS5_ARATH	Enhanced disease susceptibility 5	11826312	EDS5, an essential component of salicylic acid-dependent signaling for disease resistance in Arabidopsis, is a member of the MATE transporter family.

P46667	ATHB5_ARATH	Homeobox-leucine zipper protein ATHB-5	16055682	Homeodomain leucine zipper class I genes in Arabidopsis. Expression patterns and phylogenetic relationships.

P23818	GRIA1_MOUSE	Glutamate receptor 1	12839988	Disruption of the endocytic protein HIP1 results in neurological deficits and decreased AMPA receptor trafficking.

P39768	OPA_DROME	Pair-rule protein odd-paired	7781900	Drosophila midgut morphogenesis requires the function of the segmentation gene odd-paired.

P01857	IGHG1_HUMAN	Ig gamma-1 chain C region	6287432	The nucleotide sequence of a human immunoglobulin C gamma1 gene.

P38983	RSSA_RAT	40S ribosomal protein SA	15548204	Cellular prion protein/laminin receptor: distribution in adult central nervous system and characterization of an isoform associated with a subtype of cortical neurons.

Q96ST3	SIN3A_HUMAN	Paired amphipathic helix protein Sin3a	12670868	Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell- proliferation factor HCF-1.

Q9HCK8	CHD8_HUMAN	Chromodomain-helicase-DNA-binding protein 8	18378692	CHD8 is an ATP-dependent chromatin remodeling factor that regulates beta-catenin target genes.

O20250	TKTC_SPIOL	Transketolase, chloroplastic	9523694	Purification, properties and in situ localization of the amphibolic enzymes D-ribulose 5-phosphate 3-epimerase and transketolase from spinach chloroplasts.

O42261	IRX3_XENLA	Iroquois-class homeodomain protein irx-3	17875669	The prepattern transcription factor Irx3 directs nephron segment identity.

O94711	GYP2_SCHPO	GTPase-activating protein gyp2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q03937	HED1_YEAST	Meiosis-specific protein HED1	16818607	Budding yeast Hed1 down-regulates the mitotic recombination machinery when meiotic recombination is impaired.

O02365	IFA2_CAEEL	Intermediate filament protein ifa-2	11427699	Essential roles for four cytoplasmic intermediate filament proteins in Caenorhabditis elegans development.

P12025	MK_MOUSE	Midkine	10683378	Neointima formation in a restenosis model is suppressed in midkine- deficient mice.

Q9USZ8	FIS1_SCHPO	Mitochondria fission 1 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O00560	SDCB1_HUMAN	Syntenin-1	10230395	A role for a PDZ protein in the early secretory pathway for the targeting of proTGF-alpha to the cell surface.

Q08199	SIL1_YEAST	Nucleotide exchange factor SIL1	10958688	Sls1p stimulates Sec63p-mediated activation of Kar2p in a conformation-dependent manner in the yeast endoplasmic reticulum.

Q03563	SPK1_CAEEL	Serine/threonine-protein kinase spk-1	11091073	SPK-1, a C. elegans SR protein kinase homologue, is essential for embryogenesis and required for germline development.

P38439	LEO1_YEAST	RNA polymerase-associated protein LEO1	11884586	Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex.

Q03386	GNDS_RAT	Ral guanine nucleotide dissociation stimulator	8094051	Characterization of a guanine nucleotide dissociation stimulator for a ras-related GTPase.

P48559	YPT11_YEAST	GTP-binding protein YPT11	18245340	Multiple pathways influence mitochondrial inheritance in budding yeast.

Q9Y644	RFNG_HUMAN	Beta-1,3-N-acetylglucosaminyltransferase radical fringe	10341080	Genomic structure, mapping, and expression analysis of the mammalian Lunatic, Manic, and Radical fringe genes.

Q94BT2	AIR12_ARATH	Auxin-induced in root cultures protein 12	12805588	Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis.

Q9NHB0	BGBP1_DROME	Gram-negative bacteria-binding protein 1	10827089	Gram-negative bacteria-binding protein, a pattern recognition receptor for lipopolysaccharide and beta-1,3-glucan that mediates the signaling for the induction of innate immune genes in Drosophila melanogaster cells.

P40347	PPAL_YEAST	Low molecular weight phosphotyrosine protein phosphatase	7629177	Cloning and characterization of a Saccharomyces cerevisiae gene encoding the low molecular weight protein-tyrosine phosphatase.

Q91820	STK6A_XENLA	Serine/threonine-protein kinase 6-A	9454730	The Xenopus protein kinase pEg2 associates with the centrosome in a cell cycle-dependent manner, binds to the spindle microtubules and is involved in bipolar mitotic spindle assembly.

Q03191	TFF3_RAT	Trefoil factor 3	9299425	Characterization of a putative receptor for intestinal trefoil factor in rat small intestine: identification by in situ binding and ligand blotting.

P09972	ALDOC_HUMAN	Fructose-bisphosphate aldolase C	15537755	Structure of human brain fructose 1,6-(bis)phosphate aldolase: linking isozyme structure with function.

Q9FE20	PBS1_ARATH	Serine/threonine-protein kinase PBS1	11359614	The Arabidopsis PBS1 resistance gene encodes a member of a novel protein kinase subfamily.

O95453	PARN_HUMAN	Poly(A)-specific ribonuclease PARN	9736620	The deadenylating nuclease (DAN) is involved in poly(A) tail removal during the meiotic maturation of Xenopus oocytes.

Q9AUE0	CALS1_ARATH	Callose synthase 1	11283334	A cell plate-specific callose synthase and its interaction with phragmoplastin.

Q9UTP3	FTA6_SCHPO	Kinetochore protein fta6	16079914	Molecular analysis of kinetochore architecture in fission yeast.

P32856	STX2_HUMAN	Syntaxin-2	8466509	Molecular cloning of human epimorphin: identification of isoforms and their unique properties.

Q02974	KHK_RAT	Ketohexokinase	9799106	Structure and alternative splicing of the ketohexokinase gene.

O60016	CLR4_SCHPO	Histone-lysine N-methyltransferase, H3 lysine-9 specific	8138176	Mutations in rik1, clr2, clr3 and clr4 genes asymmetrically derepress the silent mating-type loci in fission yeast.

Q9PRS8	OC17_CHICK	Ovocleidin-17	7648490	Purification and immunochemistry of a soluble matrix protein of the chicken eggshell (ovocleidin 17).

P83404	DEFI_PHLDU	Defensin	15557638	Characterization of a defensin from the sand fly Phlebotomus duboscqi induced by challenge with bacteria or the protozoan parasite Leishmania major.

Q12959	DLG1_HUMAN	Disks large homolog 1	10779557	Characterization of PDZ-binding kinase, a mitotic kinase.

Q09669	ADH4_SCHPO	Alcohol dehydrogenase 4	15040954	A distinct type of alcohol dehydrogenase, adh4+, complements ethanol fermentation in an adh1-deficient strain of Schizosaccharomyces pombe.

P51610	HCFC1_HUMAN	Host cell factor 1	15960975	Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

Q6DD04	ILF3B_XENLA	Interleukin enhancer-binding factor 3-B	8631310	Overexpression of poly(A) binding protein prevents maturation- specific deadenylation and translational inactivation in Xenopus oocytes.

Q8GUU2	RIE1_ARATH	E3 ubiquitin protein ligase RIE1	14756305	A RING-H2 zinc-finger protein gene RIE1 is essential for seed development in Arabidopsis.

O59792	YCO1_SCHPO	Uncharacterized protein C364.01	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O14936	CSKP_HUMAN	Peripheral plasma membrane protein CASK	9660868	Human CASK/LIN-2 binds syndecan-2 and protein 4.1 and localizes to the basolateral membrane of epithelial cells.

Q9UNL4	ING4_HUMAN	Inhibitor of growth protein 4	12750254	p29ING4 and p28ING5 bind to p53 and p300, and enhance p53 activity.

Q24049	AMN_DROME	Amnesiac neuropeptides	7754370	A neuropeptide gene defined by the Drosophila memory mutant amnesiac.

Q96A70	ADC_HUMAN	Arginine decarboxylase	11587527	Expression of a novel human ornithine decarboxylase-like protein in the central nervous system and testes.

P07311	ACYP1_HUMAN	Acylphosphatase-1	3026468	A new acylphosphatase isoenzyme from human erythrocytes: purification, characterization, and primary structure.

P14778	IL1R1_HUMAN	Interleukin-1 receptor type 1	9062194	A new cytokine-receptor binding mode revealed by the crystal structure of the IL-1 receptor with an antagonist.

P52298	NCBP2_HUMAN	Nuclear cap-binding protein subunit 2	12374755	Large-scale induced fit recognition of an m(7)GpppG cap analogue by the human nuclear cap-binding complex.

P20965	PABPA_XENLA	Polyadenylate-binding protein 1-A	8631310	Overexpression of poly(A) binding protein prevents maturation- specific deadenylation and translational inactivation in Xenopus oocytes.

P53799	FDFT_ARATH	Squalene synthase	9363754	Cloning and characterization of the Arabidopsis thaliana SQS1 gene encoding squalene synthase -- involvement of the C-terminal region of the enzyme in the channeling of squalene through the sterol pathway.

P11348	DHPR_RAT	Dihydropteridine reductase	3680258	Structural studies and isolation of cDNA clones providing the complete sequence of rat liver dihydropteridine reductase.

Q86U42	PABP2_HUMAN	Polyadenylate-binding protein 2	10205180	Influenza A virus NS1 protein targets poly(A)-binding protein II of the cellular 3'-end processing machinery.

Q9M5K3	DLDH1_ARATH	Dihydrolipoyl dehydrogenase 1, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q95QJ7	GPR1_CAEEL	G-protein regulator 1	12730122	A complex of LIN-5 and GPR proteins regulates G protein signaling and spindle function in C elegans.

Q9WVE0	AICDA_MOUSE	Activation-induced cytidine deaminase	10373455	Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells.

Q9QYS9	QKI_MOUSE	Protein quaking	11892011	Quaking is essential for blood vessel development.

Q9P202	WHRN_HUMAN	Whirlin	16434480	The DFNB31 gene product whirlin connects to the Usher protein network in the cochlea and retina by direct association with USH2A and VLGR1.

P0AE01	TRMJ_ECOLI	tRNA (cytidine/uridine-2'-O-)-methyltransferase trmJ	16848900	The yfhQ gene of Escherichia coli encodes a tRNA:Cm32/Um32 methyltransferase.

Q570R7	PIF7_ARATH	Transcription factor PIF7	18252845	The Arabidopsis phytochrome-interacting factor PIF7, together with PIF3 and PIF4, regulates responses to prolonged red light by Modulating phyb levels.

Q9P3W5	TEL2_SCHPO	DNA replication checkpoint protein tel2	18076573	Rapamycin sensitivity of the Schizosaccharomyces pombe tor2 mutant and organization of two highly phosphorylated TOR complexes by specific and common subunits.

Q93YN9	IPPK_ARATH	Inositol-pentakisphosphate 2-kinase	16107538	Generation of phytate-free seeds in Arabidopsis through disruption of inositol polyphosphate kinases.

Q8N4X5	AF1L2_HUMAN	Actin filament-associated protein 1-like 2	17412687	XB130, a novel adaptor protein for signal transduction.

Q8K4Y5	LGI1_RAT	Leucine-rich glioma-inactivated protein 1	12217514	The novel EPTP repeat defines a superfamily of proteins implicated in epileptic disorders.

O94335	STT3_SCHPO	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit stt3	10234787	Schizosaccharomyces pombe stt3+ is a functional homologue of Saccharomyces cerevisiae STT3 which regulates oligosaccharyltransferase activity.

Q90ZE2	ZN703_DANRE	Zinc finger protein 703	15042707	nlz gene family is required for hindbrain patterning in the zebrafish.

P0A8P6	XERC_ECOLI	Tyrosine recombinase xerC	8402918	Two related recombinases are required for site-specific recombination at dif and cer in E. coli K12.

Q94A76	GORK_ARATH	Potassium channel GORK	14596925	Regulation of the ABA-sensitive Arabidopsis potassium channel gene GORK in response to water stress.

Q8TE54	S26A7_HUMAN	Anion exchange transporter	16524946	Chloride/bicarbonate exchanger SLC26A7 is localized in endosomes in medullary collecting duct cells and is targeted to the basolateral membrane in hypertonicity and potassium depletion.

Q8I3Z1	MLRR1_PLAF7	MATH and LRR domain-containing protein PFE0570w	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

P53609	PGTB1_HUMAN	Geranylgeranyl transferase type-1 subunit beta	8106351	cDNA cloning and expression of rat and human protein geranylgeranyltransferase type-I.

P70475	MYT1L_RAT	Myelin transcription factor 1-like protein	8631881	A novel family of Cys-Cys, His-Cys zinc finger transcription factors expressed in developing nervous system and pituitary gland.

Q570C0	TIR1_ARATH	Protein TRANSPORT INHIBITOR RESPONSE 1	15917798	The Arabidopsis F-box protein TIR1 is an auxin receptor.

Q8I0P1	SPAST_DROME	Spastin	15823537	The Drosophila homologue of the hereditary spastic paraplegia protein, spastin, severs and disassembles microtubules.

P34708	TRA1_CAEEL	Sex-determining transformer protein 1	1339311	Molecular analysis of the C. elegans sex-determining gene tra-1: a gene encoding two zinc finger proteins.

Q9BUQ8	DDX23_HUMAN	Probable ATP-dependent RNA helicase DDX23	9409622	The human U5 snRNP-specific 100-kD protein is an RS domain- containing, putative RNA helicase with significant homology to the yeast splicing factor Prp28p.

Q96301	SPY_ARATH	Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY	15608330	Cross talk between gibberellin and cytokinin: the Arabidopsis GA response inhibitor SPINDLY plays a positive role in cytokinin signaling.

P14832	CYPH_YEAST	Peptidyl-prolyl cis-trans isomerase	2687115	Yeast cyclophilin: isolation and characterization of the protein, cDNA and gene.

O43048	YH51_SCHPO	TBC domain-containing protein C215.01	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q13029	PRDM2_HUMAN	PR domain zinc finger protein 2	8654390	cDNA cloning of a novel protein containing two zinc-finger domains that may function as a transcription factor for the human heme- oxygenase-1 gene.

P62634	CNBP_RAT	Cellular nucleic acid-binding protein	7788528	Cloning and characterization of rat cellular nucleic acid binding protein (CNBP) cDNA.

Q6WGI9	KA113_PARGR	Potassium channel toxin alpha-KTx 11.3	14561751	A subfamily of acidic alpha-K(+) toxins.

P13569	CFTR_HUMAN	Cystic fibrosis transmembrane conductance regulator	19398555	The deubiquitinating enzyme USP10 regulates the post-endocytic sorting of cystic fibrosis transmembrane conductance regulator in airway epithelial cells.

P39731	MTW1_YEAST	Kinetochore-associated protein MTW1	14633972	Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes.

Q02866	MUK1_YEAST	Protein MUK1	14562095	Global analysis of protein localization in budding yeast.

O75385	ULK1_HUMAN	Serine/threonine-protein kinase ULK1	9693035	Human ULK1, a novel serine/threonine kinase related to UNC-51 kinase of Caenorhabditis elegans: cDNA cloning, expression, and chromosomal assignment.

Q9XTF3	MBK2_CAEEL	Dual specificity tyrosine-phosphorylation-regulated kinase mbk-2	14697358	The minibrain kinase homolog, mbk-2, is required for spindle positioning and asymmetric cell division in early C. elegans embryos.

P83565	RM40_RAT	39S ribosomal protein L40, mitochondrial	9857009	Mammalian mitochondrial ribosomal proteins. N-terminal amino acid sequencing, characterization, and identification of corresponding gene sequences.

Q3U285	LCORL_MOUSE	Ligand-dependent nuclear receptor corepressor-like protein	12560079	Identification and characterization of Mlr1,2: two mouse homologues of Mblk-1, a transcription factor from the honeybee brain.

Q15637	SF01_HUMAN	Splicing factor 1	9660765	The transcriptional repressor ZFM1 interacts with and modulates the ability of EWS to activate transcription.

Q06481	APLP2_HUMAN	Amyloid-like protein 2	7702756	A human amyloid precursor-like protein is highly homologous to a mouse sequence-specific DNA-binding protein.

Q03104	MSC1_YEAST	Meiotic sister chromatid recombination protein 1	10511544	Genetic control of recombination partner preference in yeast meiosis. Isolation and characterization of mutants elevated for meiotic unequal sister-chromatid recombination.

O22469	MSI3_ARATH	WD-40 repeat-containing protein MSI3	18223036	Characterization of Arabidopsis and rice DWD proteins and their roles as substrate receptors for CUL4-RING E3 ubiquitin ligases.

P07882	CEL_RAT	Bile salt-activated lipase	2688744	Molecular cloning and expression of cDNA for rat pancreatic cholesterol esterase.

Q9Y3E0	GOT1B_HUMAN	Vesicle transport protein GOT1B	12761501	Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.

O14802	RPC1_HUMAN	DNA-directed RNA polymerase III subunit RPC1	19609254	RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate.

P37304	PAM1_YEAST	Protein PAM1	8106383	Overexpression of yeast PAM1 gene permits survival without protein phosphatase 2A and induces a filamentous phenotype.

O74555	BBP_SCHPO	Branchpoint-bridging protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q10953	WRM1_CAEEL	Armadillo repeat-containing protein wrm-1	17276345	Cortical beta-catenin and APC regulate asymmetric nuclear beta- catenin localization during asymmetric cell division in C. elegans.

Q93ZD7	MRS24_ARATH	Magnesium transporter MRS2-4	19966073	A root-expressed magnesium transporter of the MRS2/MGT gene family in Arabidopsis thaliana allows for growth in low-Mg2+ environments.

Q99JB8	PACN3_MOUSE	Protein kinase C and casein kinase II substrate protein 3	11082044	All three PACSIN isoforms bind to endocytic proteins and inhibit endocytosis.

Q96RS0	TGS1_HUMAN	Trimethylguanosine synthase	12943661	Different isoforms of PRIP-interacting protein with methyltransferase domain/trimethylguanosine synthase localize to the cytoplasm and nucleus.

P83654	ERVC_TABDI	Ervatamin-C	9836431	Purification and characterization of a highly stable cysteine protease from the latex of Ervatamia coronaria.

Q99MV1	TDRD1_MOUSE	Tudor domain-containing protein 1	17038506	Tdrd1/Mtr-1, a tudor-related gene, is essential for male germ-cell differentiation and nuage/germinal granule formation in mice.

Q925U4	EDEM1_MOUSE	ER degradation-enhancing alpha-mannosidase-like 1	11375934	A novel ER alpha-mannosidase-like protein accelerates ER-associated degradation.

Q12171	MDM32_YEAST	Mitochondrial distribution and morphology protein 32	11907266	Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae.

P32521	PAN1_YEAST	Actin cytoskeleton-regulatory complex protein PAN1	10594004	Pan1p, End3p, and Sla1p, three yeast proteins required for normal cortical actin cytoskeleton organization, associate with each other and play essential roles in cell wall morphogenesis.

Q69ZN7	MYOF_MOUSE	Myoferlin	18502764	The endocytic recycling protein EHD2 interacts with myoferlin to regulate myoblast fusion.

Q8C863	ITCH_MOUSE	E3 ubiquitin-protein ligase Itchy	17137798	Ndfip1 protein promotes the function of itch ubiquitin ligase to prevent T cell activation and T helper 2 cell-mediated inflammation.

O15105	SMAD7_HUMAN	Mothers against decapentaplegic homolog 7	9256479	Vascular MADs: two novel MAD-related genes selectively inducible by flow in human vascular endothelium.

Q9FIJ0	RBOHD_ARATH	Respiratory burst oxidase homolog protein D	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P63279	UBC9_HUMAN	SUMO-conjugating enzyme UBC9	8565643	Cloning, expression, and mapping of UBE2I, a novel gene encoding a human homologue of yeast ubiquitin-conjugating enzymes which are critical for regulating the cell cycle.

Q23985	DTX_DROME	Protein deltex	7671825	Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats.

Q01970	PLCB3_HUMAN	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3	7607669	Genomic organization and complete cDNA sequence of the human phosphoinositide-specific phospholipase C beta 3 gene (PLCB3).

Q86LE4	DEFI_BOOMI	Defensin	14642886	Cysteine-rich antimicrobial peptides of the cattle tick Boophilus microplus: isolation, structural characterization and tissue expression profile.

Q8BHN3	GANAB_MOUSE	Neutral alpha-glucosidase AB	9148925	Identification of the CD45-associated 116-kDa and 80-kDa proteins as the alpha- and beta-subunits of alpha-glucosidase II.

Q9P6P2	RRP36_SCHPO	rRNA biogenesis protein rrp36	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q94A97	UBC35_ARATH	Ubiquitin-conjugating enzyme E2 35	16339806	Genome analysis and functional characterization of the E2 and RING- type E3 ligase ubiquitination enzymes of Arabidopsis.

Q8N9N2	ASCC1_HUMAN	Activating signal cointegrator 1 complex subunit 1	12077347	Novel transcription coactivator complex containing activating signal cointegrator 1.

Q9UBE8	NLK_HUMAN	Serine/threonine-protein kinase NLK	15082531	Wnt-1 signal induces phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK.

P27638	SPK1_SCHPO	Mitogen-activated protein kinase spk1	1899230	Fission yeast genes that confer resistance to staurosporine encode an AP-1-like transcription factor and a protein kinase related to the mammalian ERK1/MAP2 and budding yeast FUS3 and KSS1 kinases.

Q96P69	GPR78_HUMAN	G-protein coupled receptor 78	17363172	Tissue distribution and functional analyses of the constitutively active orphan G protein coupled receptors, GPR26 and GPR78.

P35181	AP1S1_YEAST	AP-1 complex subunit sigma-1	10564262	Adaptor complex-independent clathrin function in yeast.

P16382	IL4RA_MOUSE	Interleukin-4 receptor subunit alpha	12242343	Expression of the suppressor of cytokine signaling-5 (SOCS5) negatively regulates IL-4-dependent STAT6 activation and Th2 differentiation.

P55075	FGF8_HUMAN	Fibroblast growth factor 8	8700553	The human FGF-8 gene localizes on chromosome 10q24 and is subjected to induction by androgen in breast cancer cells.

Q9V3C1	VHL_DROME	Protein Vhl	10851083	Tracheal development and the von Hippel-Lindau tumor suppressor homolog in Drosophila.

Q15477	SKIV2_HUMAN	Helicase SKI2W	7610041	Human helicase gene SKI2W in the HLA class III region exhibits striking structural similarities to the yeast antiviral gene SKI2 and to the human gene KIAA0052: emergence of a new gene family.

Q90Z05	VNG2B_XENLA	Vang-like protein 2-B	15854914	Planar cell polarity genes regulate polarized extracellular matrix deposition during frog gastrulation.

O74331	RLP1_SCHPO	DNA repair protein rlp1	16710300	Sws1 is a conserved regulator of homologous recombination in eukaryotic cells.

Q86L04	TRAP1_DICDI	TNF receptor-associated protein 1 homolog, mitochondrial	12372338	Unique behavior of a dictyostelium homologue of TRAP-1, coupling with differentiation of D. discoideum cells.

Q09750	PST1_SCHPO	Paired amphipathic helix protein pst1	12773392	Alp13, an MRG family protein, is a component of fission yeast Clr6 histone deacetylase required for genomic integrity.

Q9SJJ3	BLH8_ARATH	BEL1-like homeodomain protein 8	16741748	Arabidopsis inflorescence architecture requires the activities of KNOX-BELL homeodomain heterodimers.

Q10658	UN119_CAEEL	Protein unc-119	8582641	Identification and cloning of unc-119, a gene expressed in the Caenorhabditis elegans nervous system.

Q9NPD3	EXOS4_HUMAN	Exosome complex exonuclease RRP41	18172165	Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'.

Q08649	ESA1_YEAST	Histone acetyltransferase ESA1	12110674	A conserved motif common to the histone acetyltransferase Esa1 and the histone deacetylase Rpd3.

P32944	SWE1_YEAST	Mitosis inhibitor protein kinase SWE1	10619027	The pachytene checkpoint in S. cerevisiae depends on Swe1-mediated phosphorylation of the cyclin-dependent kinase Cdc28.

O75629	CREG1_HUMAN	Protein CREG1	9710587	A cellular repressor of E1A-stimulated genes that inhibits activation by E2F.

Q8LAS8	SFGH_ARATH	S-formylglutathione hydrolase	11888210	Cloning and characterization of an S-formylglutathione hydrolase from Arabidopsis thaliana.

P29295	HRR25_YEAST	Casein kinase I homolog HRR25	1887218	HRR25, a putative protein kinase from budding yeast: association with repair of damaged DNA.

Q63089	S22A1_RAT	Solute carrier family 22 member 1	10997918	Localization of organic cation transporters OCT1 and OCT2 in rat kidney.

Q02796	LGE1_YEAST	Transcriptional regulatory protein LGE1	12535538	A conserved RING finger protein required for histone H2B monoubiquitination and cell size control.

Q9UUA9	TSR2_SCHPO	Pre-rRNA-processing protein tsr2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O75521	PECI_HUMAN	Peroxisomal 3,2-trans-enoyl-CoA isomerase	10419495	Characterization of PECI, a novel monofunctional D3,D2-enoyl-CoA isomerase of mammalian peroxisomes.

Q92889	XPF_HUMAN	DNA repair endonuclease XPF	19595721	Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair.

P06314	KV404_HUMAN	Ig kappa chain V-IV region B17	2997713	Detection of a unique human V kappa IV germline gene by a cloned cDNA probe.

P40395	RIC1_YEAST	Protein RIC1	11160819	Ric1p and the Ypt6p GTPase function in a common pathway required for localization of trans-Golgi network membrane proteins.

Q16763	UBE2S_HUMAN	Ubiquitin-conjugating enzyme E2 S	19822757	Identification of a physiological E2 module for the human anaphase- promoting complex.

O55242	SGMR1_MOUSE	Sigma non-opioid intracellular receptor 1	14622179	Generation and phenotypic analysis of sigma receptor type I (sigma 1) knockout mice.

Q64678	CP1B1_RAT	Cytochrome P450 1B1	7744798	Identification of a rat adrenal cytochrome P450 active in polycyclic hydrocarbon metabolism as rat CYP1B1. Demonstration of a unique tissue-specific pattern of hormonal and aryl hydrocarbon receptor- linked regulation.

O80448	PDX11_ARATH	Pyridoxal biosynthesis protein PDX1.1	16766694	Analysis of the Arabidopsis rsr4-1/pdx1-3 mutant reveals the critical function of the PDX1 protein family in metabolism, development, and vitamin B6 biosynthesis.

Q16795	NDUA9_HUMAN	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial	8486360	Construction and evaluation of a hncDNA library of human 12p transcribed sequences derived from a somatic cell hybrid.

A2APF3	CTCFL_MOUSE	Transcriptional repressor CTCFL	17048991	The testis-specific factor CTCFL cooperates with the protein methyltransferase PRMT7 in H19 imprinting control region methylation.

P35626	ARBK2_HUMAN	Beta-adrenergic receptor kinase 2	8427589	Molecular cloning, functional expression and mRNA analysis of human beta-adrenergic receptor kinase 2.

Q03088	SVL3_YEAST	Styryl dye vacuolar localization protein 3	14562095	Global analysis of protein localization in budding yeast.

Q14207	NPAT_HUMAN	Protein NPAT	15988025	HiNF-P directly links the cyclin E/CDK2/p220NPAT pathway to histone H4 gene regulation at the G1/S phase cell cycle transition.

Q9WVI9	JIP1_MOUSE	C-Jun-amino-terminal kinase-interacting protein 1	10827173	Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction.

P24100	CDKA1_ARATH	Cyclin-dependent kinase A-1	9753775	ICK1, a cyclin-dependent protein kinase inhibitor from Arabidopsis thaliana interacts with both Cdc2a and CycD3, and its expression is induced by abscisic acid.

Q9STS3	CDC23_ARATH	Anaphase-promoting complex subunit 8	14508008	The Arabidopsis anaphase-promoting complex or cyclosome: molecular and genetic characterization of the APC2 subunit.

Q9H9L7	AKIR1_HUMAN	Akirin-1	18066067	Akirins are highly conserved nuclear proteins required for NF-kappaB- dependent gene expression in Drosophila and mice.

Q12408	NPC2_YEAST	Phosphatidylglycerol/phosphatidylinositol transfer protein	14562095	Global analysis of protein localization in budding yeast.

Q9NR63	CP26B_HUMAN	Cytochrome P450 26B1	10823918	Identification of the human cytochrome P450, P450RAI-2, which is predominantly expressed in the adult cerebellum and is responsible for all-trans-retinoic acid metabolism.

P35182	PP2C1_YEAST	Protein phosphatase 2C homolog 1	8196609	TPD1 of Saccharomyces cerevisiae encodes a protein phosphatase 2C- like activity implicated in tRNA splicing and cell separation.

Q969R5	LMBL2_HUMAN	Lethal(3)malignant brain tumor-like protein 2	19233876	Methylation-state-specific recognition of histones by the MBT repeat protein L3MBTL2.

Q8BG40	KTNB1_MOUSE	Katanin p80 WD40-containing subunit B1	16203747	Recruitment of katanin p60 by phosphorylated NDEL1, an LIS1 interacting protein, is essential for mitotic cell division and neuronal migration.

P39517	DHH1_YEAST	ATP-dependent RNA helicase DHH1	12032091	The DEAD box protein Dhh1 stimulates the decapping enzyme Dcp1.

O55227	UNC50_RAT	Protein unc-50 homolog	10980252	UNCL, the mammalian homologue of UNC-50, is an inner nuclear membrane RNA-binding protein.

Q54GP3	SPRE_DICDI	Sepiapterin reductase	16527408	Functional role of sepiapterin reductase in the biosynthesis of tetrahydropteridines in Dictyostelium discoideum Ax2.

Q9H9E1	ANRA2_HUMAN	Ankyrin repeat family A protein 2	11095640	Characterization of ANKRA, a novel ankyrin repeat protein that interacts with the cytoplasmic domain of megalin.

P11792	SCH9_YEAST	Serine/threonine-protein kinase SCH9	3290050	SCH9, a gene of Saccharomyces cerevisiae that encodes a protein distinct from, but functionally and structurally related to, cAMP- dependent protein kinase catalytic subunits.

Q8C7M3	TRIM9_MOUSE	E3 ubiquitin-protein ligase TRIM9	20085810	TRIM9, a novel brain-specific E3 ubiquitin ligase, is repressed in the brain of Parkinson's disease and dementia with Lewy bodies.

P07098	LIPG_HUMAN	Gastric triacylglycerol lipase	3304425	Molecular cloning of a human gastric lipase and expression of the enzyme in yeast.

Q9JLN4	PGRP1_RAT	Peptidoglycan recognition protein 1	11145837	The cloning of a rat peptidoglycan recognition protein (PGRP) and its induction in brain by sleep deprivation.

Q7Z202	CUPC_DICDI	Calcium up-regulated protein C	14871937	The Ca2+/calcineurin-regulated cup gene family in Dictyostelium discoideum and its possible involvement in development.

O14776	TCRG1_HUMAN	Transcription elongation regulator 1	9315662	CA150, a nuclear protein associated with the RNA polymerase II holoenzyme, is involved in Tat-activated human immunodeficiency virus type 1 transcription.

Q9EQF4	FOLR4_MOUSE	Probable folate receptor delta	11111049	Identification of two putative novel folate receptor genes in humans and mouse.

P28659	CELF1_MOUSE	CUGBP Elav-like family member 1	17130239	Inactivation of CUG-BP1/CELF1 causes growth, viability, and spermatogenesis defects in mice.

Q9FLP0	MA651_ARATH	65-kDa microtubule-associated protein 1	16098102	Modulated targeting of GFP-AtMAP65-1 to central spindle microtubules during division.

P47165	XPT1_YEAST	Xanthine phosphoribosyltransferase 1	10217799	Isolation and characterization of the Saccharomyces cerevisiae XPT1 gene encoding xanthine phosphoribosyl transferase.

P13185	KIN1_YEAST	Serine/threonine protein kinase KIN1	8203145	Characterization of the KIN2 gene product in Saccharomyces cerevisiae and comparison between the kinase activities of p145KIN1 and p145KIN2.

O65554	CIPK6_ARATH	CBL-interacting serine/threonine-protein kinase 6	11115898	Interaction specificity of Arabidopsis calcineurin B-like calcium sensors and their target kinases.

O16850	FOXO_CAEEL	Forkhead box protein O	19252938	Feeding a ROS-generator to Caenorhabditis elegans leads to increased expression of small heat shock protein HSP-16.2 and hormesis.

P09759	EPHB1_RAT	Ephrin type-B receptor 1	2485255	Novel protein-tyrosine kinase cDNAs related to fps/fes and eph cloned using anti-phosphotyrosine antibody.

Q8WXH2	JPH3_HUMAN	Junctophilin-3	10891348	Characterization of human junctophilin subtype genes.

Q15906	VPS72_HUMAN	Vacuolar protein sorting-associated protein 72 homolog	7702631	Molecular cloning of a novel human cDNA on chromosome 1q21 and its mouse homolog encoding a nuclear protein with DNA-binding ability.

P36372	TAP2_RAT	Antigen peptide transporter 2	1758495	Restoration of antigen presentation to the mutant cell line RMA-S by an MHC-linked transporter.

Q9D4H1	EXOC2_MOUSE	Exocyst complex component 2	12624092	Structure of the GTPase-binding domain of Sec5 and elucidation of its Ral binding site.

O60765	Z354A_HUMAN	Zinc finger protein 354A	9919311	Molecular cloning of a zinc finger gene eZNF from a human inner ear cDNA library, and in situ expression pattern of its mouse homologue in mouse inner ear.

Q9JMB7	PIWL1_MOUSE	Piwi-like protein 1	16787948	Interplay of PIWI/Argonaute protein MIWI and kinesin KIF17b in chromatoid bodies of male germ cells.

Q9QZ39	SIA7A_MOUSE	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1	10788794	Molecular cloning and genomic analysis of mouse GalNAc alpha-2,6- sialyltransferase (ST6GalNAc I).

P24387	CRHBP_HUMAN	Corticotropin-releasing factor-binding protein	1846945	Cloning and characterization of the cDNAs for human and rat corticotropin releasing factor-binding proteins.

P35271	RS18_YEAST	40S ribosomal protein S18	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

P83382	PVK1_LOCMI	Periviscerokinin-1	11897380	Identification of the abundant neuropeptide from abdominal perisympathetic organs of locusts.

O49840	APK2B_ARATH	Protein kinase 2B, chloroplastic	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q3E834	YOS1_YEAST	Protein transport protein YOS1	15659647	Yos1p is a novel subunit of the Yip1p-Yif1p complex and is required for transport between the endoplasmic reticulum and the Golgi complex.

Q23982	PEB2_DROME	Ejaculatory bulb-specific protein 2	7619487	Method for attachment of microscopic preparations on glass for in situ hybridization, PRINS and in situ PCR studies.

Q940H6	SRK2E_ARATH	Serine/threonine-protein kinase SRK2E	15292193	Identification of nine sucrose nonfermenting 1-related protein kinases 2 activated by hyperosmotic and saline stresses in Arabidopsis thaliana.

P0C5I2	GMPPB_PIG	Mannose-1-phosphate guanyltransferase beta	11082198	Cloning, expression and characterization of the pig liver GDP-mannose pyrophosphorylase. Evidence that GDP-mannose and GDP-Glc pyrophosphorylases are different proteins.

Q63619	COQ7_RAT	Ubiquinone biosynthesis protein COQ7 homolog	8660658	Isolation and sequencing of the rat Coq7 gene and the mapping of mouse Coq7 to chromosome 7.

P10664	RL4A_YEAST	60S ribosomal protein L4-A	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

P33981	TTK_HUMAN	Dual specificity protein kinase TTK	18243099	Mps1 phosphorylates Borealin to control Aurora B activity and chromosome alignment.

P35817	BDF1_YEAST	Bromodomain-containing factor 1	7816623	The yeast BDF1 gene encodes a transcription factor involved in the expression of a broad class of genes including snRNAs.

Q9V9W8	PYGO_DROME	Protein pygopus	12015286	Pygopus, a nuclear PHD-finger protein required for wingless signaling in Drosophila.

Q8LFD3	ATB23_ARATH	Homeobox-leucine zipper protein ATHB-23	17387478	ATHB23, an Arabidopsis class I homeodomain-leucine zipper gene, is expressed in the adaxial region of young leaves.

P32505	NAB2_YEAST	Nuclear polyadenylated RNA-binding protein NAB2	8474438	NAB2: a yeast nuclear polyadenylated RNA-binding protein essential for cell viability.

P51810	GP143_HUMAN	G-protein coupled receptor 143	7647783	Cloning of the gene for ocular albinism type 1 from the distal short arm of the X chromosome.

P06104	UBC2_YEAST	Ubiquitin-conjugating enzyme E2 2	14752010	Rad6 plays a role in transcriptional activation through ubiquitylation of histone H2B.

Q9FT73	RQL2_ARATH	ATP-dependent DNA helicase Q-like 2	11058127	Molecular characterisation of RecQ homologues in Arabidopsis thaliana.

P39995	EAF5_YEAST	Chromatin modification-related protein EAF5	14562095	Global analysis of protein localization in budding yeast.

Q9Y5M6	TISR_HUMAN	Oculomedin	10362512	A novel gene (oculomedin) induced by mechanical stretching in human trabecular cells of the eye.

Q8NI29	FBX27_HUMAN	F-box only protein 27	18203720	Diversity in tissue expression, substrate binding, and SCF complex formation for a lectin family of ubiquitin ligases.

Q39255	SKP1A_ARATH	SKP1-like protein 1A	17410169	Mechanism of auxin perception by the TIR1 ubiquitin ligase.

Q12213	RL7B_YEAST	60S ribosomal protein L7-B	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

O15217	GSTA4_HUMAN	Glutathione S-transferase A4	9480897	Identification of cDNAs encoding two human alpha class glutathione transferases (GSTA3 and GSTA4) and the heterologous expression of GSTA4-4.

P37351	RPIB_ECOLI	Ribose-5-phosphate isomerase B	8576032	Ribose catabolism of Escherichia coli: characterization of the rpiB gene encoding ribose phosphate isomerase B and of the rpiR gene, which is involved in regulation of rpiB expression.

P50613	CDK7_HUMAN	Cell division protein kinase 7	9852112	Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.

P42775	GBF2_ARATH	G-box-binding factor 2	1373374	Heterodimerization between light-regulated and ubiquitously expressed Arabidopsis GBF bZIP proteins.

O75477	ERLN1_HUMAN	Erlin-1	16835267	Erlin-1 and erlin-2 are novel members of the prohibitin family of proteins that define lipid-raft-like domains of the ER.

Q9P246	STIM2_HUMAN	Stromal interaction molecule 2	11463338	Identification and characterization of the STIM (stromal interaction molecule) gene family: coding for a novel class of transmembrane proteins.

P32851	STX1A_RAT	Syntaxin-1A	10746715	Three-dimensional structure of the neuronal-Sec1-syntaxin 1a complex.

P01570	IFN14_HUMAN	Interferon alpha-14	6163083	The structure of eight distinct cloned human leukocyte interferon cDNAs.

P22612	KAPCG_HUMAN	cAMP-dependent protein kinase catalytic subunit gamma	9598317	The gene encoding the C gamma catalytic subunit of cAMP-dependent protein kinase is a transcribed retroposon.

Q04005	LIC4_YEAST	Protein ATC1/LIC4	11065362	Mutational and hyperexpression-induced disruption of bipolar budding in yeast.

P38646	GRP75_HUMAN	Stress-70 protein, mitochondrial	7829505	Cloning and subcellular localization of human mitochondrial hsp70.

P54843	MAF_MOUSE	Transcription factor Maf	10603348	Regulation of mouse lens fiber cell development and differentiation by the Maf gene.

P21932	ADCY3_RAT	Adenylate cyclase type 3	2255909	Identification of a specialized adenylyl cyclase that may mediate odorant detection.

P62829	RL23_HUMAN	60S ribosomal protein L23	1874450	Isolation and analysis of a human cDNA highly homologous to the yeast gene encoding L17A ribosomal protein.

Q9M9F5	NCED9_ARATH	9-cis-epoxycarotenoid dioxygenase NCED9, chloroplastic	12834401	Molecular characterization of the Arabidopsis 9-cis epoxycarotenoid dioxygenase gene family.

Q92831	KAT2B_HUMAN	Histone acetyltransferase KAT2B	8684459	A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A.

Q6VMQ6	MCAF1_HUMAN	Activating transcription factor 7-interacting protein 1	10976766	A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening.

P32641	RAD24_YEAST	Checkpoint protein RAD24	10660302	A novel Rad24 checkpoint protein complex closely related to replication factor C.

O82798	ARR4_ARATH	Two-component response regulator ARR4	14973166	Type-A Arabidopsis response regulators are partially redundant negative regulators of cytokinin signaling.

P46944	TRS85_YEAST	Transport protein particle 85 kDa subunit	8619313	GSG1, a yeast gene required for sporulation.

P00747	PLMN_HUMAN	Plasminogen	12456874	Effects of deletion of streptokinase residues 48-59 on plasminogen activation.

Q38796	LUMI_ARATH	Homeobox protein LUMINIDEPENDENS	7907507	Isolation of LUMINIDEPENDENS: a gene involved in the control of flowering time in Arabidopsis.

Q42290	MPPB_ARATH	Probable mitochondrial-processing peptidase subunit beta	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P54781	ERG5_YEAST	Cytochrome P450 61	8635732	Cloning and characterization of the Saccharomyces cerevisiae C-22 sterol desaturase gene, encoding a second cytochrome P-450 involved in ergosterol biosynthesis.

P58908	LECA_DIORO	Lectin alpha chain	9575151	Diocleinae lectins are a group of proteins with conserved binding sites for the core trimannoside of asparagine-linked oligosaccharides and differential specificities for complex carbohydrates.

Q9NWZ3	IRAK4_HUMAN	Interleukin-1 receptor-associated kinase 4	16286016	IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST 2 and induces T helper type 2-associated cytokines.

P0AEN8	FUCM_ECOLI	L-fucose mutarotase	12738765	Crystal structures of RbsD leading to the identification of cytoplasmic sugar-binding proteins with a novel folding architecture.

Q9P7I0	YIT2_SCHPO	Ankyrin repeat-containing protein C105.02c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q03825	MSS11_YEAST	Transcription activator MSS11	9342405	MSS11, a novel yeast gene involved in the regulation of starch metabolism.

Q9EPB4	ASC_MOUSE	Apoptosis-associated speck-like protein containing a CARD	11139337	Murine ortholog of ASC, a CARD-containing protein, self-associates and exhibits restricted distribution in developing mouse embryos.

Q9BYI3	HYCCI_HUMAN	Hyccin	10910037	Isolation and characterization of a novel human gene, DRCTNNB1A, the expression of which is down-regulated by beta-catenin.

P38247	SLM4_YEAST	Protein SLM4	14562095	Global analysis of protein localization in budding yeast.

Q04671	P_HUMAN	P protein	7601462	Organization and sequence of the human P gene and identification of a new family of transport proteins.

Q9JLJ2	AL9A1_MOUSE	4-trimethylaminobutyraldehyde dehydrogenase	10702312	Molecular and biochemical characterization of rat gamma- trimethylaminobutyraldehyde dehydrogenase and evidence for the involvement of human aldehyde dehydrogenase 9 in carnitine biosynthesis.

P21695	GPDA_HUMAN	Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic	7772607	Molecular cloning, sequencing and expression of a cDNA encoding a human liver NAD-dependent alpha-glycerol-3-phosphate dehydrogenase.

Q92820	GGH_HUMAN	Gamma-glutamyl hydrolase	8816764	Human gamma-glutamyl hydrolase: cloning and characterization of the enzyme expressed in vitro.

P18106	FPS_DROME	Tyrosine-protein kinase Fps85D	9038371	The DFer gene of Drosophila melanogaster encodes two membrane- associated proteins that can both transform vertebrate cells.

Q24008	INAD_DROME	Inactivation-no-after-potential D protein	9010208	Requirement for the PDZ domain protein, INAD, for localization of the TRP store-operated channel to a signaling complex.

P29340	UBCX_YEAST	Ubiquitin-conjugating enzyme E2-21 kDa	1326082	The Pas2 protein essential for peroxisome biogenesis is related to ubiquitin-conjugating enzymes.

O82663	DHSA1_ARATH	Succinate dehydrogenase [ubiquinone] flavoprotein subunit 1, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q8WQ86	EB1_DICDI	Microtubule-associated protein RP/EB family member 1	12134070	Dictyostelium EB1 is a genuine centrosomal component required for proper spindle formation.

Q03380	COMI_DICDI	Comitin	8635456	Linking microfilaments to intracellular membranes: the actin-binding and vesicle-associated protein comitin exhibits a mannose-specific lectin activity.

Q1MTN8	YGC1_SCHPO	UPF0661 TPR repeat-containing protein C16D10.01c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8BYI6	PCAT2_MOUSE	Lysophosphatidylcholine acyltransferase 2	17182612	A single enzyme catalyzes both platelet-activating factor production and membrane biogenesis of inflammatory cells. Cloning and characterization of acetyl-CoA:lyso-PAF acetyltransferase.

P83266	PRT31_HYDCO	Sperm protamine R3 isoform 1	8875866	The primary structure of a chondrichthyan protamine: a new apparent contradiction in protamine evolution.

P32939	YPT7_YEAST	GTP-binding protein YPT7	7489715	The GTPase Ypt7p of Saccharomyces cerevisiae is required on both partner vacuoles for the homotypic fusion step of vacuole inheritance.

Q61733	RT31_MOUSE	28S ribosomal protein S31, mitochondrial	8567980	Imogen 38: a novel 38-kD islet mitochondrial autoantigen recognized by T cells from a newly diagnosed type 1 diabetic patient.

Q9JLP1	KHDR3_RAT	KH domain-containing, RNA-binding, signal transduction-associated protein 3	10332027	T-STAR/ETOILE: a novel relative of SAM68 that interacts with an RNA- binding protein implicated in spermatogenesis.

Q96T60	PNKP_HUMAN	Bifunctional polynucleotide phosphatase/kinase	10446193	Molecular characterization of a human DNA kinase.

Q6VVB1	NHLC1_HUMAN	E3 ubiquitin-protein ligase NHLRC1	15930137	Insights into Lafora disease: malin is an E3 ubiquitin ligase that ubiquitinates and promotes the degradation of laforin.

Q15102	PA1B3_HUMAN	Platelet-activating factor acetylhydrolase IB subunit gamma	7669037	cDNA cloning of human cytosolic platelet-activating factor acetylhydrolase gamma-subunit and its mRNA expression in human tissues.

Q15646	OASL_HUMAN	59 kDa 2'-5'-oligoadenylate synthase-like protein	7776974	Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor.

P52011	CYP3_CAEEL	Peptidyl-prolyl cis-trans isomerase 3	10574961	Biochemical and structural characterization of a divergent loop cyclophilin from Caenorhabditis elegans.

O88544	CSN4_MOUSE	COP9 signalosome complex subunit 4	9707402	The COP9 complex is conserved between plants and mammals and is related to the 26S proteasome regulatory complex.

Q14865	ARI5B_HUMAN	AT-rich interactive domain-containing protein 5B	10329386	The novel Mrf-2 DNA-binding domain recognizes a five-base core sequence through major and minor-groove contacts.

Q14191	WRN_HUMAN	Werner syndrome ATP-dependent helicase	9618508	Nucleolar localization of the Werner syndrome protein in human cells.

Q8T0S6	HIPPO_DROME	Serine/threonine-protein kinase hippo	12941273	hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts.

Q12834	CDC20_HUMAN	Cell division cycle protein 20 homolog	7513050	A novel mammalian protein, p55CDC, present in dividing cells is associated with protein kinase activity and has homology to the Saccharomyces cerevisiae cell division cycle proteins Cdc20 and Cdc4.

O60636	TSN2_HUMAN	Tetraspanin-2	9714763	Sequences and expression of six new members of the tetraspanin/TM4SF family.

Q06128	TRPE_SULSO	Anthranilate synthase component 1	10449718	The crystal structure of anthranilate synthase from Sulfolobus solfataricus: functional implications.

P08842	STS_HUMAN	Steryl-sulfatase	9252398	Characterization of point mutations in patients with X-linked ichthyosis. Effects on the structure and function of the steroid sulfatase protein.

Q9LIE5	FHY3_ARATH	Protein FAR-RED ELONGATED HYPOCOTYL 3	18715961	Discrete and essential roles of the multiple domains of Arabidopsis FHY3 in mediating phytochrome A signal transduction.

P33765	AA3R_HUMAN	Adenosine receptor A3	8399349	cDNA cloning and sequence analysis of the human A3 adenosine receptor.

P23352	KALM_HUMAN	Anosmin-1	1922361	A gene deleted in Kallmann's syndrome shares homology with neural cell adhesion and axonal path-finding molecules.

Q13003	GRIK3_HUMAN	Glutamate receptor, ionotropic kainate 3	11124978	Unequal expression of allelic kainate receptor GluR7 mRNAs in human brains.

P48381	RFX3_MOUSE	Transcription factor RFX3	15121860	The transcription factor RFX3 directs nodal cilium development and left-right asymmetry specification.

Q96B97	SH3K1_HUMAN	SH3 domain-containing kinase-binding protein 1	10679202	Cloning and characterization of a novel adaptor protein, CIN85, that interacts with c-Cbl.

P36130	CAF4_YEAST	CCR4-associated factor 4	16009724	The WD40 protein Caf4p is a component of the mitochondrial fission machinery and recruits Dnm1p to mitochondria.

Q55168	PHY1_SYNY3	Phytochrome-like protein cph1	9278513	A cyanobacterial phytochrome two-component light sensory system.

P36095	VPS24_YEAST	Vacuolar protein-sorting-associated protein 24	9606181	The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function.

O75530	EED_HUMAN	Polycomb protein EED	15385962	Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity.

P37299	QCR10_YEAST	Cytochrome b-c1 complex subunit 10	8175712	Isolation and characterization of QCR10, the nuclear gene encoding the 8.5-kDa subunit 10 of the Saccharomyces cerevisiae cytochrome bc1 complex.

P07954	FUMH_HUMAN	Fumarate hydratase, mitochondrial	3828494	Nucleotide sequence of a cDNA coding for mitochondrial fumarase from human liver.

P32345	PP4C_YEAST	Serine/threonine-protein phosphatase 4 catalytic subunit	7941742	The Saccharomyces cerevisiae gene PPH3 encodes a protein phosphatase with properties different from PPX, PP1 and PP2A.

O59774	YPS1_SCHPO	Aspartic proteinase yapsin-1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9FIP9	ATR2_ARATH	Transcription factor ATR2	20360743	NINJA connects the co-repressor TOPLESS to jasmonate signalling.

O13943	AVL9_SCHPO	Late secretory pathway protein avl9	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9SZD4	PRS4A_ARATH	26S proteasome regulatory subunit 4 homolog A	17971041	26S proteasome regulatory particle mutants have increased oxidative stress tolerance.

Q9US60	KLP3_SCHPO	Kinesin-like protein 3	10641037	A fission yeast kinesin affects Golgi membrane recycling.

A0MES8	ABI4_ARATH	Ethylene-responsive transcription factor ABI4	16113213	Enhancing Arabidopsis salt and drought stress tolerance by chemical priming for its abscisic acid responses.

Q09472	EP300_HUMAN	Histone acetyltransferase p300	15075319	Positive and negative modulation of the transcriptional activity of the ETS factor ESE-1 through interaction with p300, CREB-binding protein, and Ku 70/86.

Q6QHK4	FIGLA_HUMAN	Factor in the germline alpha	15044608	Increased expression of the FIGLA transcription factor is associated with primordial follicle formation in the human fetal ovary.

Q9H479	FN3K_HUMAN	Fructosamine-3-kinase	11016445	Identification, cloning, and heterologous expression of a mammalian fructosamine-3-kinase.

P87061	TEA1_SCHPO	Tip elongation aberrant protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P98177	FOXO4_HUMAN	Forkhead box protein O4	16054032	Phenotypic modulation of smooth muscle cells through interaction of Foxo4 and myocardin.

O88900	GRB14_RAT	Growth factor receptor-bound protein 14	9748281	Identification of the rat adapter Grb14 as an inhibitor of insulin actions.

Q9Y3B2	EXOS1_HUMAN	3'-5' exoribonuclease CSL4 homolog	15231747	A protein interaction framework for human mRNA degradation.

Q92585	MAML1_HUMAN	Mastermind-like protein 1	11101851	MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors.

O15151	MDM4_HUMAN	Protein Mdm4	10608892	Stabilization of the MDM2 oncoprotein by interaction with the structurally related MDMX protein.

Q12406	ARP7_YEAST	Actin-related protein 7	10619019	Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains.

P07261	GCR1_YEAST	Glycolytic genes transcriptional activator GCR1	8508768	GCR1, a transcriptional activator in Saccharomyces cerevisiae, complexes with RAP1 and can function without its DNA binding domain.

Q08357	S20A2_HUMAN	Sodium-dependent phosphate transporter 2	8302848	A human amphotropic retrovirus receptor is a second member of the gibbon ape leukemia virus receptor family.

P21139	MA2C1_RAT	Alpha-mannosidase 2C1	2211613	Isolation, characterization, and expression of cDNA encoding a rat liver endoplasmic reticulum alpha-mannosidase.

P21541	ZYG11_CAEEL	Early embryogenesis protein zyg-11	17304241	The Caenorhabditis elegans cell-cycle regulator ZYG-11 defines a conserved family of CUL-2 complex components.

P70288	HDAC2_MOUSE	Histone deacetylase 2	9702189	SAP30, a component of the mSin3 corepressor complex involved in N- CoR-mediated repression by specific transcription factors.

Q6UVJ0	SAS6_HUMAN	Spindle assembly abnormal protein 6 homolog	16244668	The Polo kinase Plk4 functions in centriole duplication.

Q60848	HELLS_MOUSE	Lymphocyte-specific helicase	11711429	Lsh, a member of the SNF2 family, is required for genome-wide methylation.

O88939	ZBT7A_MOUSE	Zinc finger and BTB domain-containing protein 7A	15662416	Role of the proto-oncogene Pokemon in cellular transformation and ARF repression.

Q39192	SRK2D_ARATH	Serine/threonine-protein kinase SRK2D	19874541	PYR/PYL/RCAR family members are major in-vivo ABI1 protein phosphatase 2C-interacting proteins in Arabidopsis.

Q91Z31	PTBP2_MOUSE	Polypyrimidine tract-binding protein 2	10829067	A brain-enriched polypyrimidine tract-binding protein antagonizes the ability of Nova to regulate neuron-specific alternative splicing.

P39715	ECM1_YEAST	Protein ECM1	14562095	Global analysis of protein localization in budding yeast.

P21674	FST_RAT	Follistatin	12867435	Crystal structures of the heparan sulfate-binding domain of follistatin. Insights into ligand binding.

P40495	LYS12_YEAST	Homoisocitrate dehydrogenase, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q07075	AMPE_HUMAN	Glutamyl aminopeptidase	8244382	cDNA cloning and expression of human glutamyl aminopeptidase (aminopeptidase A).

P84274	PA1A_RANPA	Palustrin-1a	11087945	Multiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris.

Q27564	KITH_DICDI	Thymidine kinase 1	17448496	Dictyostelium discoideum salvages purine deoxyribonucleosides by highly specific bacterial-like deoxyribonucleoside kinases.

P00387	NB5R3_HUMAN	NADH-cytochrome b5 reductase 3	1400360	Enzymatic instability of NADH-cytochrome b5 reductase as a cause of hereditary methemoglobinemia type I (red cell type).

O75192	PX11A_HUMAN	Peroxisomal membrane protein 11A	9714566	Clofibrate-inducible, 28-kDa peroxisomal integral membrane protein is encoded by PEX11.

Q8VZU3	SCP19_ARATH	Serine carboxypeptidase-like 19	11696189	The sng2 mutant of Arabidopsis is defective in the gene encoding the serine carboxypeptidase-like protein sinapoylglucose:choline sinapoyltransferase.

P15807	MET8_YEAST	Siroheme biosynthesis protein MET8	11980703	The structure of Saccharomyces cerevisiae Met8p, a bifunctional dehydrogenase and ferrochelatase.

Q99252	ECM3_YEAST	Protein ECM3	14562095	Global analysis of protein localization in budding yeast.

Q10336	MCP6_SCHPO	Meiotic coiled-coil protein 6	15654021	Mcp6, a meiosis-specific coiled-coil protein of Schizosaccharomyces pombe, localizes to the spindle pole body and is required for horsetail movement and recombination.

P17948	VGFR1_HUMAN	Vascular endothelial growth factor receptor 1	2158038	Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family.

P12075	COX5B_RAT	Cytochrome c oxidase subunit 5B, mitochondrial	8206867	Molecular cloning and characterization of the rat cytochrome c oxidase subunit Vb gene.

Q9NPI6	DCP1A_HUMAN	mRNA-decapping enzyme 1A	12417715	Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay.

Q925S4	IL24_MOUSE	Interleukin-24	11342597	FISP (IL-4-induced secreted protein), a novel cytokine-like molecule secreted by Th2 cells.

P22509	FBRL_RAT	rRNA 2'-O-methyltransferase fibrillarin	10679015	Conserved composition of mammalian box H/ACA and box C/D small nucleolar ribonucleoprotein particles and their interaction with the common factor Nopp140.

Q07950	YEH2_YEAST	Sterol esterase 2	15713625	The Saccharomyces cerevisiae YLL012/YEH1, YLR020/YEH2, and TGL1 genes encode a novel family of membrane-anchored lipases that are required for steryl ester hydrolysis.

P39878	PA2GC_RAT	Group IIC secretory phospholipase A2	8083202	Cloning and characterization of novel rat and mouse low molecular weight Ca(2+)-dependent phospholipase A2s containing 16 cysteines.

P81449	ATPJ_YEAST	ATP synthase subunit e, mitochondrial	9857174	Yeast mitochondrial F1F0-ATPase exists as a dimer: identification of three dimer-specific subunits.

P49768	PSN1_HUMAN	Presenilin-1	7596406	Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease.

P61794	LPAR1_RAT	Lysophosphatidic acid receptor 1	9753172	A rat G protein-coupled receptor selectively expressed in myelin- forming cells.

Q9SRT0	PUB9_ARATH	U-box domain-containing protein 9	14657406	A large complement of the predicted Arabidopsis ARM repeat proteins are members of the U-box E3 ubiquitin ligase family.

P91943	PANG1_DROME	Protein pangolin, isoforms A/H/I	9118222	Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF.

O60119	YH75_SCHPO	Vesicle-associated membrane protein-associated protein C16G5.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q16773	KAT1_HUMAN	Kynurenine--oxoglutarate transaminase 1	7883047	Molecular cloning and expression of a cDNA for human kidney cysteine conjugate beta-lyase.

P60484	PTEN_HUMAN	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	19345329	Rak functions as a tumor suppressor by regulating PTEN protein stability and function.

O42905	RTI1_SCHPO	DNA repair and recombination protein rti1	14551247	Schizosaccharomyces pombe Rdh54 (TID1) acts with Rhp54 (RAD54) to repair meiotic double-strand breaks.

P57740	NU107_HUMAN	Nuclear pore complex protein Nup107	11684705	Novel vertebrate nucleoporins Nup133 and Nup160 play a role in mRNA export.

Q01954	BNC1_HUMAN	Zinc finger protein basonuclin-1	1332044	Basonuclin: a keratinocyte protein with multiple paired zinc fingers.

P54829	PTN5_HUMAN	Tyrosine-protein phosphatase non-receptor type 5	16441242	Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases.

P53350	PLK1_HUMAN	Serine/threonine-protein kinase PLK1	19473992	Plk1-mediated phosphorylation of Topors regulates p53 stability.

Q3V3I2	GNAT3_MOUSE	Guanine nucleotide-binding protein G(t) subunit alpha-3	8657284	Transduction of bitter and sweet taste by gustducin.

Q8TCD1	CR032_HUMAN	UPF0729 protein C18orf32	12761501	Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.

O82122	VSP2_ARATH	Vegetative storage protein 2	9747802	Arabidopsis thaliana vegetative storage protein (VSP) genes: gene organization and tissue-specific expression.

Q13349	ITAD_HUMAN	Integrin alpha-D	9841932	Alphadbeta2 integrin is expressed on human eosinophils and functions as an alternative ligand for vascular cell adhesion molecule 1 (VCAM- 1).

Q9JJF3	NO66_MOUSE	Lysine-specific demethylase NO66	19927124	Regulation of the osteoblast-specific transcription factor Osterix by NO66, a Jumonji family histone demethylase.

Q8K3Y7	TNF15_RAT	Tumor necrosis factor ligand superfamily member 15	11911831	TL1A is a TNF-like ligand for DR3 and TR6/DcR3 and functions as a T cell costimulator.

P02829	HSP82_YEAST	ATP-dependent molecular chaperone HSP82	14562095	Global analysis of protein localization in budding yeast.

Q10241	CMB1_SCHPO	Mismatch-binding protein cmb1	9804804	The high mobility group domain protein cmb1 of Schizosaccharomyces pombe binds to cytosines in base mismatches and opposite chemically altered guanines.

Q71RI9	KAT3_MOUSE	Kynurenine--oxoglutarate transaminase 3	19029248	Biochemical and structural properties of mouse kynurenine aminotransferase III.

P47816	PDCD2_RAT	Programmed cell death protein 2	2072913	Identification of mRNAs associated with programmed cell death in immature thymocytes.

Q9R257	HEBP1_MOUSE	Heme-binding protein 1	9813049	Molecular characterizatin of a newly identified heme-binding protein induced during differentiation of Murine erythroleukemia cells.

Q9LES3	AI5L2_ARATH	ABSCISIC ACID-INSENSITIVE 5-like protein 2	15642716	Characterization of three homologous basic leucine zipper transcription factors (bZIP) of the ABI5 family during Arabidopsis thaliana embryo maturation.

P13501	CCL5_HUMAN	C-C motif chemokine 5	7524281	Platelets secrete an eosinophil-chemotactic cytokine which is a member of the C-C-chemokine family.

P53045	ERG25_YEAST	C-4 methylsterol oxidase	8663358	Characterization of yeast methyl sterol oxidase (ERG25) and identification of a human homologue.

Q925H1	TRPS1_MOUSE	Zinc finger transcription factor Trps1	12885770	The RING finger protein RNF4, a co-regulator of transcription, interacts with the TRPS1 transcription factor.

P23493	MBR1_YEAST	Protein MBR1	8208248	MBR1 and MBR3, two related yeast genes that can suppress the growth defect of hap2, hap3 and hap4 mutants.

P15515	HIS1_HUMAN	Histatin-1	3286634	Histatins, a novel family of histidine-rich proteins in human parotid secretion. Isolation, characterization, primary structure, and fungistatic effects on Candida albicans.

O14405	GUN4_TRIRE	Endoglucanase-4	9370370	cDNA cloning of a Trichoderma reesei cellulase and demonstration of endoglucanase activity by expression in yeast.

Q9NRA8	4ET_HUMAN	Eukaryotic translation initiation factor 4E transporter	10856257	A novel shuttling protein, 4E-T, mediates the nuclear import of the mRNA 5' cap-binding protein, eIF4E.

P25578	PGPS1_YEAST	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	9799363	Phosphatidylglycerolphosphate synthase encoded by the PEL1/PGS1 gene in Saccharomyces cerevisiae is localized in mitochondria and its expression is regulated by phospholipid precursors.

Q9VS38	MED4_DROME	Mediator of RNA polymerase II transcription subunit 4	15477388	A high resolution protein interaction map of the yeast Mediator complex.

P05981	HEPS_HUMAN	Serine protease hepsin	1885621	Hepsin, a cell membrane-associated protease. Characterization, tissue distribution, and gene localization.

Q9NRM7	LATS2_HUMAN	Serine/threonine-protein kinase LATS2	19739119	Molecular characterization of human homologs of yeast MOB1.

P53235	EIF2A_YEAST	Eukaryotic translation initiation factor 2A	12133843	Characterization of mammalian eIF2A and identification of the yeast homolog.

P11229	ACM1_HUMAN	Muscarinic acetylcholine receptor M1	15086532	Identification of a novel family of G protein-coupled receptor associated sorting proteins.

P04650	RL39_YEAST	60S ribosomal protein L39	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

P59530	TA2R7_MOUSE	Taste receptor type 2 member 7	11854532	Expression of bitter taste receptors of the T2R family in the gastrointestinal tract and enteroendocrine STC-1 cells.

Q03135	CAV1_HUMAN	Caveolin-1	17287217	Caveolin-1 triggers T-cell activation via CD26 in association with CARMA1.

Q9URZ2	YI09_SCHPO	UPF0654 protein C869.09	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q62219	TGFI1_MOUSE	Transforming growth factor beta-1-induced transcript 1 protein	15687259	Hic-5 regulates an epithelial program mediated by PPARgamma.

P38297	FZO1_YEAST	Transmembrane GTPase FZO1	15087460	Ugo1p links the Fzo1p and Mgm1p GTPases for mitochondrial fusion.

O35945	AL1A7_MOUSE	Aldehyde dehydrogenase, cytosolic 1	10191271	Molecular analysis of two closely related mouse aldehyde dehydrogenase genes: identification of a role for Aldh1, but not Aldh- pb, in the biosynthesis of retinoic acid.

Q03062	HES5_RAT	Transcription factor HES-5	1400497	Molecular characterization of a rat negative regulator with a basic helix-loop-helix structure predominantly expressed in the developing nervous system.

Q5SW45	MKS1_MOUSE	Meckel syndrome type 1 protein homolog	17185389	The Meckel-Gruber syndrome proteins MKS1 and meckelin interact and are required for primary cilium formation.

P04233	HG2A_HUMAN	HLA class II histocompatibility antigen gamma chain	12782713	MIF signal transduction initiated by binding to CD74.

Q07527	TRM3_YEAST	tRNA guanosine-2'-O-methyltransferase TRM3	14562095	Global analysis of protein localization in budding yeast.

P07004	PROA_ECOLI	Gamma-glutamyl phosphate reductase	6089111	Analysis of the Escherichia coli proBA locus by DNA and protein sequencing.

Q14435	GALT3_HUMAN	Polypeptide N-acetylgalactosaminyltransferase 3	16638743	Polypeptide GalNAc-transferase T3 and familial tumoral calcinosis. Secretion of fibroblast growth factor 23 requires O-glycosylation.

P31749	AKT1_HUMAN	RAC-alpha serine/threonine-protein kinase	20059950	The E3 ligase TTC3 facilitates ubiquitination and degradation of phosphorylated Akt.

P06780	RHO1_YEAST	GTP-binding protein RHO1	8621575	Activation of yeast protein kinase C by Rho1 GTPase.

Q8R507	FKTN_MOUSE	Fukutin	12471058	Functional requirements for fukutin-related protein in the Golgi apparatus.

Q9EPC2	FGF23_MOUSE	Fibroblast growth factor 23	17086194	Klotho converts canonical FGF receptor into a specific receptor for FGF23.

Q04697	GSF2_YEAST	Glucose-signaling factor 2	10377429	Efficient export of the glucose transporter Hxt1p from the endoplasmic reticulum requires Gsf2p.

P01909	DQA1_HUMAN	HLA class II histocompatibility antigen, DQ alpha 1 chain	6415485	The heavy chain of human B-cell alloantigen HLA-DS has a variable N- terminal region and a constant immunoglobulin-like region.

P28331	NDUS1_HUMAN	NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

Q00322	CEBPD_MOUSE	CCAAT/enhancer-binding protein delta	19641492	Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-beta transcriptional complex.

Q03944	VPS64_YEAST	Vacuolar protein sorting-associated protein 64	12514182	Bipartite signals mediate subcellular targeting of tail-anchored membrane proteins in Saccharomyces cerevisiae.

Q80WJ1	GGN_MOUSE	Gametogenetin	12574169	Mouse GGN1 and GGN3, two germ cell-specific proteins from the single gene Ggn, interact with mouse POG and play a role in spermatogenesis.

Q9HCG7	GBA2_HUMAN	Non-lysosomal glucosylceramidase	11489889	Molecular cloning and expression of human bile acid beta -glucosidase.

P27824	CALX_HUMAN	Calnexin	8136357	Human, mouse, and rat calnexin cDNA cloning: identification of potential calcium binding motifs and gene localization to human chromosome 5.

P84039	ENPP5_RAT	Ectonucleotide pyrophosphatase/phosphodiesterase family member 5	12927778	Characterization of nucleotide pyrophosphatase-5 as an oligomannosidic glycoprotein in rat brain.

O00305	CACB4_HUMAN	Voltage-dependent L-type calcium channel subunit beta-4	9628818	Calcium channel beta4 (CACNB4): human ortholog of the mouse epilepsy gene lethargic.

P0CAX5	OPHN1_RAT	Oligophrenin-1	19487570	The Rho-linked mental retardation protein oligophrenin-1 controls synapse maturation and plasticity by stabilizing AMPA receptors.

O14359	YB4E_SCHPO	Uncharacterized AIM2 family protein C30D10.14	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9SL05	PGR5_ARATH	Protein PROTON GRADIENT REGULATION 5, chloroplastic	12176323	PGR5 is involved in cyclic electron flow around photosystem I and is essential for photoprotection in Arabidopsis.

P63252	IRK2_HUMAN	Inward rectifier potassium channel 2	7696590	Molecular cloning and expression of a human heart inward rectifier potassium channel.

Q7Z494	NPHP3_HUMAN	Nephrocystin-3	12872122	Mutations in a novel gene, NPHP3, cause adolescent nephronophthisis, tapeto-retinal degeneration and hepatic fibrosis.

Q943E6	HS16B_ORYSJ	16.9 kDa class I heat shock protein 2	15803416	Characterization of the genomic structures and selective expression profiles of nine class I small heat shock protein genes clustered on two chromosomes in rice (Oryza sativa L.).

Q13425	SNTB2_HUMAN	Beta-2-syntrophin	11043403	The receptor tyrosine phosphatase-like protein ICA512 binds the PDZ domains of beta2-syntrophin and nNOS in pancreatic beta-cells.

P86036	IELA_ASPFL	Elastase inhibitor AFLEI	17287718	Characterization and primary structure of elastase inhibitor, AFLEI, from Aspergillus flavus.

Q7Z1M0	VIT1_SOLIN	Vitellogenin-1	11249942	Characterization of vitellogenin in the red imported fire ant, Solenopsis invicta (Hymenoptera: Apocrita: Formicidae).

Q9VBW3	CAD96_DROME	Tyrosine kinase receptor Cad96Ca	9731193	Sampling the genomic pool of protein tyrosine kinase genes using the polymerase chain reaction with genomic DNA.

Q96242	CP74A_ARATH	Allene oxide synthase, chloroplastic	10420644	Structure and regulation of the Arabidopsis thaliana allene oxide synthase gene.

Q03772	CWC15_YEAST	Pre-mRNA-splicing factor CWC15	11884590	Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

Q9LSG3	GAUT8_ARATH	Galacturonosyltransferase 8	12368506	QUASIMODO1 encodes a putative membrane-bound glycosyltransferase required for normal pectin synthesis and cell adhesion in Arabidopsis.

Q9H840	GEMI7_HUMAN	Gem-associated protein 7	12065586	Identification and characterization of Gemin7, a novel component of the survival of motor neuron complex.

Q940H6	SRK2E_ARATH	Serine/threonine-protein kinase SRK2E	16682349	The identification of genes involved in the stomatal response to reduced atmospheric relative humidity.

O88685	PRS6A_MOUSE	26S protease regulatory subunit 6A	10945464	Mouse proteasomal ATPases Psmc3 and Psmc4: genomic organization and gene targeting.

Q9P6I2	DUG1_SCHPO	Cys-Gly metallodipeptidase dug1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P93835	DRE1B_ARATH	Dehydration-responsive element-binding protein 1B	9735350	An Arabidopsis gene family encoding DRE/CRT binding proteins involved in low-temperature -responsive gene expression.

Q9H2X3	CLC4M_HUMAN	C-type lectin domain family 4 member M	11337487	Extensive repertoire of membrane-bound and soluble dendritic cell- specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts.

P08567	PLEK_HUMAN	Pleckstrin	8615792	Phosphorylation of human pleckstrin on Ser-113 and Ser-117 by protein kinase C.

Q94JM3	ARFB_ARATH	Auxin response factor 2	16176952	AUXIN RESPONSE FACTOR1 and AUXIN RESPONSE FACTOR2 regulate senescence and floral organ abscission in Arabidopsis thaliana.

Q96GD4	AURKB_HUMAN	Serine/threonine-protein kinase 12	16179162	Septin1, a new interaction partner for human serine/threonine kinase aurora-B.

P18408	MET16_YEAST	Phosphoadenosine phosphosulfate reductase	2203779	Gene-enzyme relationship in the sulfate assimilation pathway of Saccharomyces cerevisiae. Study of the 3'-phosphoadenylylsulfate reductase structural gene.

P12843	IBP2_RAT	Insulin-like growth factor-binding protein 2	2426267	Purification and amino-terminal sequence of an insulin-like growth factor-binding protein secreted by rat liver BRL-3A cells.

Q8C5D8	PIAS2_MOUSE	E3 SUMO-protein ligase PIAS2	15767674	Ikaros SUMOylation: switching out of repression.

Q8ST66	ABCGI_DICDI	ABC transporter G family member 18	11719559	ABC transporters required for endocytosis and endosomal pH regulation in Dictyostelium.

Q00444	HXC5_HUMAN	Homeobox protein Hox-C5	1346761	The upstream region of the human homeobox gene HOX3D is a target for regulation by retinoic acid and HOX homeoproteins.

P28241	IDH2_YEAST	Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial	11502169	Yeast mitochondrial dehydrogenases are associated in a supramolecular complex.

Q8GUJ2	CRR2_ARATH	Cysteine-rich repeat secretory protein 2	18266921	Arabidopsis proteins important for modulating defense responses to Pseudomonas syringae that secrete HopW1-1.

P60467	SC61B_CANFA	Protein transport protein Sec61 subunit beta	8107851	Evolutionary conservation of components of the protein translocation complex.

Q03900	YD132_YEAST	Uncharacterized protein YDR132C	14562095	Global analysis of protein localization in budding yeast.

Q09683	RAD32_SCHPO	DNA repair protein rad32	12944482	The fission yeast Rad32 (Mre11)-Rad50-Nbs1 complex is required for the S-phase DNA damage checkpoint.

Q03942	RKM2_YEAST	Ribosomal N-lysine methyltransferase 2	17005568	A novel SET domain methyltransferase in yeast: Rkm2-dependent trimethylation of ribosomal protein L12ab at lysine 10.

P40041	YEP4_YEAST	Putative transcription factor YER064C	14562095	Global analysis of protein localization in budding yeast.

P53129	MON1_YEAST	Vacuolar fusion protein MON1	12134085	Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae.

P34237	CASP_YEAST	Protein CASP	12429822	CASP, the alternatively spliced product of the gene encoding the CCAAT-displacement protein transcription factor, is a Golgi membrane protein related to giantin.

Q9QXM1	JMY_MOUSE	Junction-mediating and -regulatory protein	17170761	Mdm2 targets the p53 transcription cofactor JMY for degradation.

P48679	LMNA_RAT	Prelamin-A/C	16128803	Proteome analysis of a rat liver nuclear insoluble protein fraction and localization of a novel protein, ISP36, to compartments in the interchromatin space.

Q9Y4G8	RPGF2_HUMAN	Rap guanine nucleotide exchange factor 2	10608883	PDZ-GEF1, a guanine nucleotide exchange factor specific for Rap1 and Rap2.

Q9NRD5	PICK1_HUMAN	PRKCA-binding protein	10623590	Interaction of the PDZ domain of human PICK1 with class I ADP- ribosylation factors.

Q63570	PRS6B_RAT	26S protease regulatory subunit 6B	8607789	Structures of the rat proteasomal ATPases: determination of highly conserved structural motifs and rules for their spacing.

Q8TAE7	KCNG3_HUMAN	Potassium voltage-gated channel subfamily G member 3	11852086	Molecular cloning and characterization of Kv6.3, a novel modulatory subunit for voltage-gated K(+) channel Kv2.1.

Q15645	TRP13_HUMAN	Thyroid receptor-interacting protein 13	9223484	Two classes of human papillomavirus type 16 E1 mutants suggest pleiotropic conformational constraints affecting E1 multimerization, E2 interaction, and interaction with cellular proteins.

Q8WUQ7	CS029_HUMAN	Uncharacterized protein C19orf29	15302935	Large-scale characterization of HeLa cell nuclear phosphoproteins.

Q9M9L0	APC11_ARATH	Anaphase-promoting complex subunit 11	14508008	The Arabidopsis anaphase-promoting complex or cyclosome: molecular and genetic characterization of the APC2 subunit.

Q9T0K5	LRX3_ARATH	Leucine-rich repeat extensin-like protein 3	16287169	Arabidopsis cell wall proteome defined using multidimensional protein identification technology.

Q9QZ08	NAGK_MOUSE	N-acetyl-D-glucosamine kinase	10824116	Molecular cloning and characterization of murine and human N- acetylglucosamine kinase.

Q9EQZ7	RIMS2_MOUSE	Regulating synaptic membrane exocytosis protein 2	12401793	Piccolo, a Ca2+ sensor in pancreatic beta-cells. Involvement of cAMP- GEFII.Rim2.Piccolo complex in cAMP-dependent exocytosis.

Q9UNS1	TIM_HUMAN	Protein timeless homolog	9856465	Mammalian circadian autoregulatory loop: a timeless ortholog and mPer1 interact and negatively regulate CLOCK-BMAL1-induced transcription.

P70582	NUP54_RAT	Nuclear pore complex protein Nup54	8707840	Molecular and functional characterization of the p62 complex, an assembly of nuclear pore complex glycoproteins.

Q8UUJ9	SDF1_XENLA	Stromal cell-derived factor 1	11859124	Xenopus laevis stromal cell-derived factor 1: conservation of structure and function during vertebrate development.

Q9Y7N7	NAR1_SCHPO	Cytosolic Fe-S cluster assembly factor NAR1 homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O60121	YH77_SCHPO	Uncharacterized protein C16G5.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q16665	HIF1A_HUMAN	Hypoxia-inducible factor 1-alpha	16543236	Histone deacetylase inhibitors repress the transactivation potential of hypoxia-inducible factors independently of direct acetylation of HIF-alpha.

P02651	APOA4_RAT	Apolipoprotein A-IV	3020028	Linkage, evolution, and expression of the rat apolipoprotein A-I, C- III, and A-IV genes.

P08067	UCRI_YEAST	Cytochrome b-c1 complex subunit Rieske, mitochondrial	10873857	Structure at 2.3 A resolution of the cytochrome bc1 complex from the yeast Saccharomyces cerevisiae co-crystallized with an antibody Fv fragment.

Q86SF2	GALT7_HUMAN	N-acetylgalactosaminyltransferase 7	10544240	A novel human UDP-N-acetyl-D-galactosamine;polypeptide N- acetylgalactosaminyltr ansferase, GalNAc-T7, with specificity for partial GalNAc-glycosylated acceptor substrates.

Q12271	INP53_YEAST	Inositol-1,4,5-trisphosphate 5-phosphatase 3	11598201	A novel mechanism for localizing membrane proteins to yeast trans- Golgi network requires function of synaptojanin-like protein.

Q12018	CDC53_YEAST	Cell division control protein 53	11283612	Skp1 forms multiple protein complexes, including RAVE, a regulator of V-ATPase assembly.

P04456	RL25_YEAST	60S ribosomal protein L25	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

P01229	LSHB_HUMAN	Lutropin subunit beta	1191677	Human pituitary lutropin. Isolation, properties, and the complete amino acid sequence of the beta-subunit.

Q9NJG9	SUZ12_DROME	Polycomb protein Su(z)12	12697833	A 1-megadalton ESC/E(Z) complex from Drosophila that contains polycomblike and RPD3.

Q9USZ3	RUXE_SCHPO	Small nuclear ribonucleoprotein E	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q5SF93	AAAP_ANAMV	Appendage-associated protein	15557651	Identification of a novel Anaplasma marginale appendage-associated protein that localizes with actin filaments during intraerythrocytic infection.

O54880	RPH3L_RAT	Rab effector Noc2	17067543	Functional involvement of Noc2, a Rab27 effector, in rat parotid acinar cells.

Q12899	TRI26_HUMAN	Tripartite motif-containing protein 26	8530076	Cloning of a new 'finger' protein gene (ZNF173) within the class I region of the human MHC.

O75132	ZBED4_HUMAN	Zinc finger BED domain-containing protein 4	19369242	ZBED4, a BED-type zinc-finger protein in the cones of the human retina.

Q9NP92	RT30_HUMAN	28S ribosomal protein S30, mitochondrial	10640817	Cloning, expression, and mapping of PDCD9, the human homolog of Gallus gallus pro-apoptotic protein p52.

P26342	TGBR3_RAT	Transforming growth factor beta receptor type 3	1657407	Expression cloning and characterization of the TGF-beta type III receptor.

O74854	POF6_SCHPO	F-box protein pof6	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P50942	INP52_YEAST	Inositol-1,4,5-trisphosphate 5-phosphatase 2	12606027	Bsp1p/Ypr171p is an adapter that directly links some synaptojanin family members to the cortical actin cytoskeleton in yeast.

Q9LY71	CKX6_ARATH	Cytokinin dehydrogenase 6	14555694	Cytokinin-deficient transgenic Arabidopsis plants show multiple developmental alterations indicating opposite functions of cytokinins in the regulation of shoot and root meristem activity.

P98066	TSG6_HUMAN	Tumor necrosis factor-inducible gene 6 protein	1730767	A novel secretory tumor necrosis factor-inducible protein (TSG-6) is a member of the family of hyaluronate binding proteins, closely related to the adhesion receptor CD44.

Q920Q2	REV1_MOUSE	DNA repair protein REV1	11711549	Mechanisms of dCMP transferase reactions catalyzed by mouse Rev1 protein.

Q9NXR8	ING3_HUMAN	Inhibitor of growth protein 3	16387653	ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.

Q9QYX7	PCLO_MOUSE	Protein piccolo	12401793	Piccolo, a Ca2+ sensor in pancreatic beta-cells. Involvement of cAMP- GEFII.Rim2.Piccolo complex in cAMP-dependent exocytosis.

Q04491	SEC13_YEAST	Protein transport protein SEC13	11389436	Dynamics of the COPII coat with GTP and stable analogues.

Q05655	KPCD_HUMAN	Protein kinase C delta type	8357834	Molecular and biochemical characterization of a recombinant human PKC-delta family member.

P04114	APOB_HUMAN	Apolipoprotein B-100	16548883	Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection.

Q12355	PST1_YEAST	Cell wall mannoprotein PST1	10383953	Amino acid residues in the omega-minus region participate in cellular localization of yeast glycosylphosphatidylinositol-attached proteins.

P02652	APOA2_HUMAN	Apolipoprotein A-II	7918467	Structure of human apolipoprotein D: locations of the intermolecular and intramolecular disulfide links.

P63279	UBC9_HUMAN	SUMO-conjugating enzyme UBC9	8798754	Molecular cloning of the cDNA and chromosome localization of the gene for human ubiquitin-conjugating enzyme 9.

P23642	VAN1_YEAST	Mannan polymerase I complex VAN1 subunit	12235155	The components of the Saccharomyces cerevisiae mannosyltransferase complex M-Pol I have distinct functions in mannan synthesis.

Q13309	SKP2_HUMAN	S-phase kinase-associated protein 2	11931757	Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication.

Q9UBP0	SPAST_HUMAN	Spastin	17389232	Recognition of C-terminal amino acids in tubulin by pore loops in Spastin is important for microtubule severing.

Q9H1B4	NXF5_HUMAN	Nuclear RNA export factor 5	11566096	NXF5, a novel member of the nuclear RNA export factor family, is lost in a male patient with a syndromic form of mental retardation.

P10275	ANDR_HUMAN	Androgen receptor	10930412	Androgen receptor interacts with a novel MYST protein, HBO1.

Q8TFH3	YIKB_SCHPO	Uncharacterized protein PB17E12.11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q923M0	PP16A_MOUSE	Protein phosphatase 1 regulatory subunit 16A	11336659	Cloning and identification of MYPT3: a prenylatable myosin targeting subunit of protein phosphatase 1.

Q04329	ICY1_YEAST	Interacting with cytoskeleton protein 1	14562095	Global analysis of protein localization in budding yeast.

Q9GQQ0	SPIN_DROME	Protein spinster	11340170	Mutations in the novel membrane protein spinster interfere with programmed cell death and cause neural degeneration in Drosophila melanogaster.

P13236	CCL4_HUMAN	C-C motif chemokine 4	2521882	Mitogenic activation of human T cells induces two closely related genes which share structural similarities with a new family of secreted factors.

P06730	IF4E_HUMAN	Eukaryotic translation initiation factor 4E	16271312	Structural basis for mRNA cap-binding regulation of eukaryotic initiation factor 4E by 4E-binding protein, studied by spectroscopic, X-ray crystal structural, and molecular dynamics simulation methods.

Q9UJP4	KLH21_HUMAN	Kelch-like protein 21	19995937	The Cul3-KLHL21 E3 ubiquitin ligase targets aurora B to midzone microtubules in anaphase and is required for cytokinesis.

P53262	VOA1_YEAST	V0 assembly protein 1	18799613	Voa1p functions in V-ATPase assembly in the yeast endoplasmic reticulum.

P13609	SRGN_MOUSE	Serglycin	17081126	Mast cell-dependent activation of pro matrix metalloprotease 2: a role for serglycin proteoglycan-dependent mast cell proteases.

Q9ER24	ATX10_RAT	Ataxin-10	15201271	Ataxin-10, the spinocerebellar ataxia type 10 neurodegenerative disorder protein, is essential for survival of cerebellar neurons.

Q12025	YD056_YEAST	Uncharacterized protein YDR056C	14562095	Global analysis of protein localization in budding yeast.

Q16649	NFIL3_HUMAN	Nuclear factor interleukin-3-regulated protein	7565758	Molecular cloning and characterization of NF-IL3A, a transcriptional activator of the human interleukin-3 promoter.

P13942	COBA2_HUMAN	Collagen alpha-2(XI) chain	10581026	Mutations in COL11A2 cause non-syndromic hearing loss (DFNA13).

P35331	NRCAM_CHICK	Neuronal cell adhesion molecule	1512296	Bravo/Nr-CAM is closely related to the cell adhesion molecules L1 and Ng-CAM and has a similar heterodimer structure.

P19174	PLCG1_HUMAN	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1	10873601	Characterization of the tyrosine kinase Tnk1 and its binding with phospholipase C-gamma1.

P11710	FUS1_YEAST	Nuclear fusion protein FUS1	2690078	The yeast cell fusion protein FUS1 is O-glycosylated and spans the plasma membrane.

P32252	RASB_DICDI	Ras-like protein rasB	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P05709	SIM_DROME	Protein single-minded	3345560	The Drosophila single-minded gene encodes a nuclear protein with sequence similarity to the per gene product.

P46059	S15A1_HUMAN	Solute carrier family 15 member 1	7896779	Human intestinal H+/peptide cotransporter. Cloning, functional expression, and chromosomal localization.

Q9C6Z1	NCED5_ARATH	Probable 9-cis-epoxycarotenoid dioxygenase NCED5, chloroplastic	12834401	Molecular characterization of the Arabidopsis 9-cis epoxycarotenoid dioxygenase gene family.

Q94AY3	DRIP2_ARATH	E3 ubiquitin protein ligase DRIP2	18552202	Arabidopsis DREB2A-interacting proteins function as RING E3 ligases and negatively regulate plant drought stress-responsive gene expression.

Q9S7Z2	AFP4_ARATH	Ninja-family protein AFP4	17195036	Overexpression of TMAC2, a novel negative regulator of abscisic acid and salinity responses, has pleiotropic effects in Arabidopsis thaliana.

Q08012	DRK_DROME	Protein enhancer of sevenless 2B	8462097	An SH3-SH2-SH3 protein is required for p21Ras1 activation and binds to sevenless and Sos proteins in vitro.

Q8R4D5	TRPM8_MOUSE	Transient receptor potential cation channel subfamily M member 8	12654248	ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures.

Q9SGD6	AROD6_ARATH	Arogenate dehydratase/prephenate dehydratase 6, chloroplastic	19136569	Tyrosine and phenylalanine are synthesized within the plastids in Arabidopsis.

O15258	RER1_HUMAN	Protein RER1	9309388	Human Rer1 is localized to the Golgi apparatus and complements the deletion of the homologous Rer1 protein of Saccharomyces cerevisiae.

Q8BX57	PXK_MOUSE	PX domain-containing protein kinase-like protein	16135750	MONaKA, a novel modulator of the plasma membrane Na,K-ATPase.

P38232	REG2_YEAST	Protein REG2	8649403	The REG2 gene of Saccharomyces cerevisiae encodes a type 1 protein phosphatase-binding protein that functions with Reg1p and the Snf1 protein kinase to regulate growth.

P45594	CADF_DROME	Cofilin/actin-depolymerizing factor homolog	8183953	Identification of Drosophila cytoskeletal proteins by induction of abnormal cell shape in fission yeast.

O94640	SIR2_SCHPO	NAD-dependent histone deacetylase sir2	12867036	Sir2 regulates histone H3 lysine 9 methylation and heterochromatin assembly in fission yeast.

O75445	USH2A_HUMAN	Usherin	12433396	Usherin expression is highly conserved in mouse and human tissues.

P32315	FXA1B_XENLA	Forkhead box protein A1-B	15656969	Of fox and frogs: fox (fork head/winged helix) transcription factors in Xenopus development.

O08966	S22A1_MOUSE	Solute carrier family 22 member 1	12176030	Functional characterization of mouse cation transporter mOCT2 compared with mOCT1.

P28647	AA3R_RAT	Adenosine receptor A3	1323836	Molecular cloning and characterization of an adenosine receptor: the A3 adenosine receptor.

O75531	BAF_HUMAN	Barrier-to-autointegration factor	9465049	A previously unidentified host protein protects retroviral DNA from autointegration.

Q00618	PGTA_YEAST	Geranylgeranyl transferase type-2 subunit alpha	8232542	Bet2p and Mad2p are components of a prenyltransferase that adds geranylgeranyl onto Ypt1p and Sec4p.

Q9V3Z6	MYO7A_DROME	Myosin-VIIa	15886106	Myosin VIIA defects, which underlie the Usher 1B syndrome in humans, lead to deafness in Drosophila.

Q10218	PPC89_SCHPO	Spindle pole body protein ppc89	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9BXY8	BEX2_HUMAN	Protein BEX2	19711341	BEX2 regulates mitochondrial apoptosis and G1 cell cycle in breast cancer.

Q9BZM4	N2DL3_HUMAN	NKG2D ligand 3	11239445	ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor.

Q9NXA8	SIRT5_HUMAN	NAD-dependent deacetylase sirtuin-5	18680753	Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5.

O13848	I3ACR_SCHPO	NAD/NADP-dependent indole-3-acetaldehyde reductase	16813561	Identification of a novel NADH-specific aldo-keto reductase using sequence and structural homologies.

O75832	PSD10_HUMAN	26S proteasome non-ATPase regulatory subunit 10	16023600	The oncoprotein gankyrin binds to MDM2/HDM2, enhancing ubiquitylation and degradation of p53.

P20809	IL11_HUMAN	Interleukin-11	1828438	Molecular cloning of cDNA encoding adipogenesis inhibitory factor and identity with interleukin-11.

Q804Q5	FEZF2_DANRE	Fez family zinc finger protein 2	12469125	Zinc finger protein too few controls the development of monoaminergic neurons.

Q61039	HAND2_MOUSE	Heart- and neural crest derivatives-expressed protein 2	9671575	A signaling cascade involving endothelin-1, dHAND and msx1 regulates development of neural-crest-derived branchial arch mesenchyme.

Q9VVR1	NOT_DROME	Ubiquitin carboxyl-terminal hydrolase nonstop	18188155	SAGA-mediated H2B deubiquitination controls the development of neuronal connectivity in the Drosophila visual system.

P40353	ATF1_YEAST	Alcohol O-acetyltransferase 1	8085822	Molecular cloning, sequence analysis, and expression of the yeast alcohol acetyltransferase gene.

P24752	THIL_HUMAN	Acetyl-CoA acetyltransferase, mitochondrial	1715688	Evidence for a structural mutation (347Ala to Thr) in a German family with 3-ketothiolase deficiency.

Q61066	NR0B1_MOUSE	Nuclear receptor subfamily 0 group B member 1	16466956	Novel role for the orphan nuclear receptor Dax1 in embryogenesis, different from steroidogenesis.

Q10666	POP1_CAEEL	Protein pop-1	15066285	Phosphorylation by the beta-catenin/MAPK complex promotes 14-3-3- mediated nuclear export of TCF/POP-1 in signal-responsive cells in C. elegans.

P08581	MET_HUMAN	Hepatocyte growth factor receptor	15314156	MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met.

O14980	XPO1_HUMAN	Exportin-1	11932251	Ran-binding protein 3 links Crm1 to the Ran guanine nucleotide exchange factor.

P19524	MYO2_YEAST	Myosin-2	2016335	The Saccharomyces cerevisiae MYO2 gene encodes an essential myosin for vectorial transport of vesicles.

P31750	AKT1_MOUSE	RAC-alpha serine/threonine-protein kinase	11282895	Reperfusion-activated Akt kinase prevents apoptosis in transgenic mouse hearts overexpressing insulin-like growth factor-1.

Q94JU3	CSN7_ARATH	COP9 signalosome complex subunit 7	12615944	Characterization of the last subunit of the Arabidopsis COP9 signalosome: implications for the overall structure and origin of the complex.

Q2QCI8	MED12_DANRE	Mediator of RNA polymerase II transcription subunit 12	17088561	A subunit of the mediator complex regulates vertebrate neuronal development.

Q13395	TARB1_HUMAN	Probable methyltransferase TARBP1	8846792	The cellular factor TRP-185 regulates RNA polymerase II binding to HIV-1 TAR RNA.

O95760	IL33_HUMAN	Interleukin-33	16286016	IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST 2 and induces T helper type 2-associated cytokines.

P19438	TNR1A_HUMAN	Tumor necrosis factor receptor superfamily member 1A	15465831	A death receptor-associated anti-apoptotic protein, BRE, inhibits mitochondrial apoptotic pathway.

P59537	T2R43_HUMAN	Taste receptor type 2 member 43	19628819	Motile cilia of human airway epithelia are chemosensory.

P01620	KV302_HUMAN	Ig kappa chain V-III region SIE	6794615	Amino acid sequence of the variable regions of light chains from two idiotypically cross-reactive human IgM anti-gamma-globulins of the Wa group.

Q920R6	VPP4_MOUSE	V-type proton ATPase 116 kDa subunit a isoform 4	11498539	a4, a unique kidney-specific isoform of mouse vacuolar H+-ATPase subunit a.

P50278	SOL1_YEAST	6-phosphogluconolactonase-like protein 1	15454531	Division of labor among the yeast Sol proteins implicated in tRNA nuclear export and carbohydrate metabolism.

O59680	CY1_SCHPO	Cytochrome c1, heme protein, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P00356	G3P_CHICK	Glyceraldehyde-3-phosphate dehydrogenase	6687938	Glyceraldehyde 3-phosphate dehydrogenase protein and mRNA are both differentially expressed in adult chickens but not chick embryos.

P08174	DAF_HUMAN	Complement decay-accelerating factor	2433596	Cloning of decay-accelerating factor suggests novel use of splicing to generate two proteins.

Q06490	THI22_YEAST	Thiamine biosynthesis protein THI22	10383756	Genetic redundancy and gene fusion in the genome of the Baker's yeast Saccharomyces cerevisiae: functional characterization of a three- member gene family involved in the thiamine biosynthetic pathway.

Q75JD5	PCKA_DICDI	Phosphoenolpyruvate carboxykinase [ATP]	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P63320	RALA_SAGOE	Ras-related protein Ral-A	15530367	Crystal structures of Ral-GppNHp and Ral-GDP reveal two binding sites that are also present in Ras and Rap.

Q8ZQQ2	SLRP_SALTY	E3 ubiquitin-protein ligase slrP	19690162	Salmonella type III secretion effector SlrP is an E3 ubiquitin ligase for mammalian thioredoxin.

Q13153	PAK1_HUMAN	Serine/threonine-protein kinase PAK 1	16278681	CRIPak, a novel endogenous Pak1 inhibitor.

Q9UPU9	SMAG1_HUMAN	Protein Smaug homolog 1	16221671	Mammalian Smaug is a translational repressor that forms cytoplasmic foci similar to stress granules.

Q8N137	CNTRB_HUMAN	Centrobin	16275750	Centrobin: a novel daughter centriole-associated protein that is required for centriole duplication.

P36048	SN114_YEAST	114 kDa U5 small nuclear ribonucleoprotein component	9233818	An evolutionarily conserved U5 snRNP-specific protein is a GTP- binding factor closely related to the ribosomal translocase EF-2.

Q8MY12	MHCKC_DICDI	Myosin heavy chain kinase C	11278493	Specific phosphorylation of threonine by the Dictyostelium myosin II heavy chain kinase family.

O43813	LANC1_HUMAN	LanC-like protein 1	9512664	Isolation, molecular characterization, and tissue-specific expression of a novel putative G protein-coupled receptor.

P54144	AMT11_ARATH	Ammonium transporter 1 member 1	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

Q9P2W7	B3GA1_HUMAN	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1	10783264	Cloning and chromosomal mapping of human glucuronyltransferase involved in biosynthesis of the HNK-1 carbohydrate epitope.

O04005	REHY_ARATH	1-Cys peroxiredoxin PER1	9580097	The expression of a peroxiredoxin antioxidant gene, AtPer1, in Arabidopsis thaliana is seed-specific and related to dormancy.

P25300	BUD5_YEAST	Bud site selection protein 5	8234337	Genetic evidence for the roles of the bud-site-selection genes BUD5 and BUD2 in control of the Rsr1p (Bud1p) GTPase in yeast.

Q09232	ORAI_CAEEL	Protein orai	17376526	Physiological roles of STIM1 and Orai1 homologs and CRAC channels in the genetic model organism Caenorhabditis elegans.

P05814	CASB_HUMAN	Beta-casein	2387396	Cloning and sequencing of a cDNA encoding human milk beta-casein.

Q42371	ERECT_ARATH	LRR receptor-like serine/threonine-protein kinase ERECTA	15998304	ERECTA receptor-like kinase and heterotrimeric G protein from Arabidopsis are required for resistance to the necrotrophic fungus Plectosphaerella cucumerina.

Q9BUR4	WAP53_HUMAN	Telomerase Cajal body protein 1	19179534	A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis.

Q9H074	PAIP1_HUMAN	Polyadenylate-binding protein-interacting protein 1	9548260	Interaction of polyadenylate-binding protein with the eIF4G homologue PAIP enhances translation.

O95633	FSTL3_HUMAN	Follistatin-related protein 3	16150905	Differential biosynthesis and intracellular transport of follistatin isoforms and follistatin-like-3.

O94378	YG0C_SCHPO	Uncharacterized protein C1604.12	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q02318	CP27A_HUMAN	Sterol 26-hydroxylase, mitochondrial	9790667	A novel arg362ser mutation in the sterol 27-hydroxylase gene (CYP27): its effects on pre-mRNA splicing and enzyme activity.

Q08647	PUS7_YEAST	Multisubstrate pseudouridine synthase 7	14562095	Global analysis of protein localization in budding yeast.

Q8LAS7	CNBL2_ARATH	Calcineurin B-like protein 2	11230129	The NAF domain defines a novel protein-protein interaction module conserved in Ca(2+)-regulated kinases.

O76064	RNF8_HUMAN	E3 ubiquitin-protein ligase RNF8	18001824	RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins.

Q6NPN9	DWA2_ARATH	WD repeat-containing protein DWA2	20525848	DWA1 and DWA2, two Arabidopsis DWD protein components of CUL4-based E3 ligases, act together as negative regulators in aba signal transduction.

A9LNK9	CPSF_ARATH	Cleavage and polyadenylation specificity factor CPSF30	16897494	The 73 kD subunit of the cleavage and polyadenylation specificity factor (CPSF) complex affects reproductive development in Arabidopsis.

P49687	NU145_YEAST	Nucleoporin NUP145	8524308	Yeast nucleoporin mutants are defective in pre-tRNA splicing.

Q61792	LASP1_MOUSE	LIM and SH3 domain protein 1	15465019	Phosphorylation of mouse LASP-1 on threonine 156 by cAMP- and cGMP- dependent protein kinase.

P25054	APC_HUMAN	Adenomatous polyposis coli protein	19632184	An EB1-binding motif acts as a microtubule tip localization signal.

Q8NHY0	B4GN2_HUMAN	Beta-1,4 N-acetylgalactosaminyltransferase 2	14688233	Molecular cloning of the human beta1,4 N- acetylgalactosaminyltransferase responsible for the biosynthesis of the Sd(a) histo-blood group antigen: the sequence predicts a very long cytoplasmic domain.

P06802	ENPP1_MOUSE	Ectonucleotide pyrophosphatase/phosphodiesterase family member 1	9662402	Mutation in Npps in a mouse model of ossification of the posterior longitudinal ligament of the spine.

P18848	ATF4_HUMAN	Cyclic AMP-dependent transcription factor ATF-4	1534408	Molecular cloning of human CREB-2: an ATF/CREB transcription factor that can negatively regulate transcription from the cAMP response element.

P37202	DIS3_SCHPO	Exosome complex exonuclease dis3	12376568	An evolutionarily conserved fission yeast protein, Ned1, implicated in normal nuclear morphology and chromosome stability, interacts with Dis3, Pim1/RCC1 and an essential nucleoporin.

P02545	LMNA_HUMAN	Prelamin-A/C	19933576	Mammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processes.

O94264	YORF_SCHPO	Uncharacterized RING finger protein P8B7.15c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q96AZ6	ISG20_HUMAN	Interferon-stimulated gene 20 kDa protein	12594219	ISG20, a new interferon-induced RNase specific for single-stranded RNA, defines an alternative antiviral pathway against RNA genomic viruses.

Q60928	GGT1_MOUSE	Gamma-glutamyltranspeptidase 1	9139708	Mice with genetic gamma-glutamyl transpeptidase deficiency exhibit glutathionuria, severe growth failure, reduced life spans, and infertility.

Q01476	UBP2_YEAST	Ubiquitin carboxyl-terminal hydrolase 2	15933713	The Rsp5 ubiquitin ligase is coupled to and antagonized by the Ubp2 deubiquitinating enzyme.

Q9USQ1	CTF18_SCHPO	Chromosome transmission fidelity protein 18	16040599	Contrasting effects of Elg1-RFC and Ctf18-RFC inactivation in the absence of fully functional RFC in fission yeast.

Q9P6R1	VRP1_SCHPO	Verprolin	12939254	The PCH family protein, Cdc15p, recruits two F-actin nucleation pathways to coordinate cytokinetic actin ring formation in Schizosaccharomyces pombe.

P15801	DPOG_YEAST	DNA polymerase gamma	2684980	Cloning and sequencing of the nuclear gene MIP1 encoding the catalytic subunit of the yeast mitochondrial DNA polymerase.

O13761	YF2B_SCHPO	Uncharacterized protein C17A2.11, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P46096	SYT1_MOUSE	Synaptotagmin-1	15466855	SV2B regulates synaptotagmin 1 by direct interaction.

A4L7R7	DEF1_PINSY	Defensin-1	19683554	Purification and molecular cloning of antimicrobial peptides from Scots pine seedlings.

O55229	CHKB_MOUSE	Choline/ethanolamine kinase	16371353	A rostrocaudal muscular dystrophy caused by a defect in choline kinase beta, the first enzyme in phosphatidylcholine biosynthesis.

Q55D99	PAKA_DICDI	Serine/threonine-protein kinase pakA	10545500	PAKa, a putative PAK family member, is required for cytokinesis and the regulation of the cytoskeleton in Dictyostelium discoideum cells during chemotaxis.

P87061	TEA1_SCHPO	Tip elongation aberrant protein 1	9200612	tea1 and the microtubular cytoskeleton are important for generating global spatial order within the fission yeast cell.

Q874R1	RHO4_SCHPO	GTP-binding protein rho4	12653963	The small GTPase Rho4 is involved in controlling cell morphology and septation in fission yeast.

Q9SZ30	HIS5_ARATH	Imidazole glycerol phosphate synthase hisHF, chloroplastic	9654139	An Arabidopsis cDNA encoding a bifunctional glutamine amidotransferase/cyclase suppresses the histidine auxotrophy of a Saccharomyces cerevisiae his7 mutant.

Q15327	ANKR1_HUMAN	Ankyrin repeat domain-containing protein 1	7730328	Identification and characterization of a novel cytokine-inducible nuclear protein from human endothelial cells.

Q7T1H5	DND1_DANRE	Dead end protein 1	18155131	RNA-binding protein Dnd1 inhibits microRNA access to target mRNA.

O76024	WFS1_HUMAN	Wolframin	9817917	Diabetes insipidus, diabetes mellitus, optic atrophy and deafness (DIDMOAD) caused by mutations in a novel gene (wolframin) coding for a predicted transmembrane protein.

P39107	MNN9_YEAST	Mannan polymerase complexes subunit MNN9	9430634	Multi-protein complexes in the cis Golgi of Saccharomyces cerevisiae with alpha-1,6-mannosyltransferase activity.

P23811	SCTR_RAT	Secretin receptor	1646711	Molecular cloning and expression of a cDNA encoding the secretin receptor.

Q8TE04	PANK1_HUMAN	Pantothenate kinase 1	14523052	PPARalpha controls the intracellular coenzyme A concentration via regulation of PANK1alpha gene expression.

P47897	SYQ_HUMAN	Glutaminyl-tRNA synthetase	8078941	Evolution of the Glx-tRNA synthetase family: the glutaminyl enzyme as a case of horizontal gene transfer.

P09466	PAEP_HUMAN	Glycodelin	3194393	Complete amino acid sequence of human placental protein 14: a progesterone-regulated uterine protein homologous to beta- lactoglobulins.

P50391	NPY4R_HUMAN	Neuropeptide Y receptor type 4	7592911	Cloning and functional expression of a human Y4 subtype receptor for pancreatic polypeptide, neuropeptide Y, and peptide YY.

Q14573	ITPR3_HUMAN	Inositol 1,4,5-trisphosphate receptor type 3	8288584	Primary structure, ligand binding, and localization of the human type 3 inositol 1,4,5-trisphosphate receptor expressed in intestinal epithelium.

Q9UP65	PA24C_HUMAN	Cytosolic phospholipase A2 gamma	10085124	Molecular cloning of two new human paralogs of 85-kDa cytosolic phospholipase A2.

Q8L785	SYGM2_ARATH	Glycyl-tRNA synthetase 2, chloroplastic/mitochondrial	9707529	Inactivation of a glycyl-tRNA synthetase leads to an arrest in plant embryo development.

Q9U1M8	MYOI_DICDI	Myosin-I heavy chain	17671169	Talin influences the dynamics of the myosin VII-membrane interaction.

Q99638	RAD9A_HUMAN	Cell cycle checkpoint control protein RAD9A	8943031	A human homolog of the Schizosaccharomyces pombe rad9+ checkpoint control gene.

Q924Z5	TRAM2_MOUSE	Translocating chain-associated membrane protein 2	14749390	TRAM2 protein interacts with endoplasmic reticulum Ca2+ pump Serca2b and is necessary for collagen type I synthesis.

P47011	GLG2_YEAST	Glycogenin-2	8524228	Requirement of the self-glucosylating initiator proteins Glg1p and Glg2p for glycogen accumulation in Saccharomyces cerevisiae.

P53142	VPS73_YEAST	Vacuolar protein sorting-associated protein 73	12134085	Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae.

Q9NQL2	RRAGD_HUMAN	Ras-related GTP-binding protein D	14660641	A novel human nucleolar protein, Nop132, binds to the G proteins, RRAG A/C/D.

P53298	OKP1_YEAST	Central kinetochore subunit OKP1	10323865	A putative protein complex consisting of Ctf19, Mcm21, and Okp1 represents a missing link in the budding yeast kinetochore.

Q9DBX1	RGC32_MOUSE	Response gene to complement 32 protein	11687586	RGC-32 increases p34CDC2 kinase activity and entry of aortic smooth muscle cells into S-phase.

B2RU80	PTPRB_MOUSE	Receptor-type tyrosine-protein phosphatase beta	17360632	Vascular endothelial tyrosine phosphatase (VE-PTP)-null mice undergo vasculogenesis but die embryonically because of defects in angiogenesis.

P38983	RSSA_RAT	40S ribosomal protein SA	925037	Isolation of eukaryotic ribosomal proteins. Purification and characterization of the 40 S ribosomal subunit proteins Sa, Sc, S3a, S3b, S5', S9, S10, S11, S12, S14, S15, S15', S16, S17, S18, S19, S20, S21, S26, S27', and S29.

Q9HCG1	ZN160_HUMAN	Zinc finger protein 160	11410164	Molecular cloning and preliminary functional analysis of two novel human KRAB zinc finger proteins, HKr18 and HKr19.

P37262	SOL2_YEAST	6-phosphogluconolactonase-like protein 2	15454531	Division of labor among the yeast Sol proteins implicated in tRNA nuclear export and carbohydrate metabolism.

O94368	YG02_SCHPO	Pentatricopeptide repeat-containing protein C1604.02c, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9SUP6	WRK53_ARATH	Probable WRKY transcription factor 53	20409006	A HECT E3 ubiquitin ligase negatively regulates Arabidopsis leaf senescence through degradation of the transcription factor WRKY53.

Q9UM47	NOTC3_HUMAN	Neurogenic locus notch homolog protein 3	17292860	Conserved signal peptide of Notch3 inhibits interaction with proteasome.

P04916	RET4_RAT	Retinol-binding protein 4	4044565	Characterization of the rat retinol-binding protein gene and its comparison to the three-dimensional structure of the protein.

O14047	PPK11_SCHPO	Serine/threonine-protein kinase ppk11	15821139	Systematic deletion analysis of fission yeast protein kinases.

Q13253	NOGG_HUMAN	Noggin	7666191	Identification of mammalian noggin and its expression in the adult nervous system.

P42345	MTOR_HUMAN	Serine/threonine-protein kinase mTOR	11853878	Characterization of ubiquilin 1, an mTOR-interacting protein.

Q13838	UAP56_HUMAN	Spliceosome RNA helicase BAT1	15870275	Human hHpr1/p84/Thoc1 regulates transcriptional elongation and physically links RNA polymerase II and RNA processing factors.

Q9JL60	GMEB1_MOUSE	Glucocorticoid modulatory element-binding protein 1	10692587	Cloning of a mouse glucocorticoid modulatory element binding protein, a new member of the KDWK family.

Q2QGD7	ZXDC_HUMAN	Zinc finger protein ZXDC	16600381	ZXDC, a novel zinc finger protein that binds CIITA and activates MHC gene transcription.

Q12508	RMD5_YEAST	Sporulation protein RMD5	12686616	Catabolite degradation of fructose-1,6-bisphosphatase in the yeast Saccharomyces cerevisiae: a genome-wide screen identifies eight novel GID genes and indicates the existence of two degradation pathways.

P31779	TTHY_RANCA	Transthyretin	11017780	Effect of diethylstilbestrol on thyroid hormone binding to amphibian transthyretins.

P00185	CP1A1_RAT	Cytochrome P450 1A1	9348277	Targeting of NH2-terminal-processed microsomal protein to mitochondria: a novel pathway for the biogenesis of hepatic mitochondrial P450MT2.

Q9WTN6	S22AL_MOUSE	Solute carrier family 22 member 21	16288981	OCTN3 is a mammalian peroxisomal membrane carnitine transporter.

Q9JJA4	WDR12_MOUSE	Ribosome biogenesis protein WDR12	11827460	Wdr12, a mouse gene encoding a novel WD-repeat protein with a notchless-like amino-terminal domain.

P53917	FAR11_YEAST	Factor arrest protein 11	12588993	Far3 and five interacting proteins prevent premature recovery from pheromone arrest in the budding yeast Saccharomyces cerevisiae.

Q54MB4	ASNS_DICDI	Probable asparagine synthetase [glutamine-hydrolyzing]	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q9Y4X4	KLF12_HUMAN	Krueppel-like factor 12	10704285	Genomic structure and DNA binding properties of the human zinc finger transcriptional repressor AP-2rep (KLF12).

O95677	EYA4_HUMAN	Eyes absent homolog 4	9887327	EYA4, a novel vertebrate gene related to Drosophila eyes absent.

Q9JK71	MAGI3_RAT	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3	15951562	Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases.

Q9H2X6	HIPK2_HUMAN	Homeodomain-interacting protein kinase 2	12220523	HIPK2 associates with RanBPM.

P18085	ARF4_HUMAN	ADP-ribosylation factor 4	2107548	Selective amplification of an mRNA and related pseudogene for a human ADP-ribosylation factor, a guanine nucleotide-dependent protein activator of cholera toxin.

Q9UBW5	BIN2_HUMAN	Bridging integrator 2	10903846	Bin2, a functionally nonredundant member of the BAR adaptor gene family.

Q8IVG9	HUNIN_HUMAN	Humanin	12732850	Humanin peptide suppresses apoptosis by interfering with Bax activation.

P10275	ANDR_HUMAN	Androgen receptor	20501646	The deubiquitinating enzyme USP26 is a regulator of androgen receptor signaling.

Q5JLP4	CKX4_ORYSJ	Cytokinin dehydrogenase 4	12721786	Structure and function of cytokinin oxidase/dehydrogenase genes of maize, rice, Arabidopsis and other species.

Q03430	RSM28_YEAST	37S ribosomal protein RSM28, mitochondrial	15701796	Alteration of a novel dispensable mitochondrial ribosomal small- subunit protein, Rsm28p, allows translation of defective COX2 mRNAs.

P03406	NEF_HV1BR	Protein Nef	11285224	Mechanism for down-regulation of CD28 by Nef.

P21451	EDNRB_RAT	Endothelin B receptor	2175397	Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor.

P04233	HG2A_HUMAN	HLA class II histocompatibility antigen gamma chain	6324166	cDNA clone for the human invariant gamma chain of class II histocompatibility antigens and its implications for the protein structure.

Q99N48	SYTL3_MOUSE	Synaptotagmin-like protein 3	11773082	The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain.

O15519	CFLAR_HUMAN	CASP8 and FADD-like apoptosis regulator	9217161	Inhibition of death receptor signals by cellular FLIP.

P53305	RT27_YEAST	Mitochondral 37S ribosomal protein S27	11278769	Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues.

Q9LX29	ACR4_ARATH	Serine/threonine-protein kinase-like protein ACR4	15772284	ARABIDOPSIS CRINKLY4 function, internalization, and turnover are dependent on the extracellular crinkly repeat domain.

P46951	YPP1_YEAST	Cargo-transport protein YPP1	17576801	YGR198w (YPP1) targets A30P alpha-synuclein to the vacuole for degradation.

P61981	1433G_HUMAN	14-3-3 protein gamma	10486217	Cloning, expression, and chromosomal mapping of the human 14-3-3gamma gene (YWHAG) to 7q11.23.

Q6UY14	ATL4_HUMAN	ADAMTS-like protein 4	16364318	Cathepsin B and its interacting proteins, bikunin and TSRC1, correlate with TNF-induced apoptosis of ovarian cancer cells OV-90.

Q9EPB5	SERHL_MOUSE	Serine hydrolase-like protein	11352564	Identification of Serhl, a new member of the serine hydrolase family induced by passive stretch of skeletal muscle in vivo.

Q9P3B2	AIM38_SCHPO	Altered inheritance rate of mitochondria protein 38 homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q68FT6	RHBG_RAT	Ammonium transporter Rh type B	12595489	RhBG and RhCG, the putative ammonia transporters, are expressed in the same cells in the distal nephron.

Q9NYG5	APC11_HUMAN	Anaphase-promoting complex subunit 11	18485873	Mechanism of ubiquitin-chain formation by the human anaphase- promoting complex.

Q03723	OST6_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST6	10358084	The oligosaccharyltransferase complex from Saccharomyces cerevisiae. Isolation of the OST6 gene, its synthetic interaction with OST3, and analysis of the native complex.

Q02161	RHD_HUMAN	Blood group Rh(D) polypeptide	1438298	Molecular cloning and primary structure of the human blood group RhD polypeptide.

Q08951	AP3D_YEAST	AP-3 complex subunit delta	9335339	The AP-3 adaptor complex is essential for cargo-selective transport to the yeast vacuole.

Q9UN42	AT1B4_HUMAN	Protein ATP1B4	17592128	Evolution of Na,K-ATPase betam-subunit into a coregulator of transcription in placental mammals.

P36543	VATE1_HUMAN	V-type proton ATPase subunit E 1	11399750	Interaction between aldolase and vacuolar H+-ATPase: evidence for direct coupling of glycolysis to the ATP-hydrolyzing proton pump.

P19334	TRP_DROME	Transient receptor potential protein	7751943	TRP, a protein essential for inositide-mediated Ca2+ influx is localized adjacent to the calcium stores in Drosophila photoreceptors.

P38728	ECM34_YEAST	Protein ECM34	9335584	Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae.

A2AJ76	HMCN2_MOUSE	Hemicentin-2	17015624	Hemicentins assemble on diverse epithelia in the mouse.

Q12247	FYV7_YEAST	rRNA-processing protein FYV7	14562095	Global analysis of protein localization in budding yeast.

Q86WD7	SPA9_HUMAN	Serpin A9	15489334	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

P13669	MNGR_ECOLI	Mannosyl-D-glycerate transport/metabolism system repressor mngR	14645248	Phosphotransferase-mediated transport of the osmolyte 2-O-alpha- mannosyl-D-glycerate in Escherichia coli occurs by the product of the mngA (hrsA) gene and is regulated by the mngR (farR) gene product acting as repressor.

Q7KU24	CHD1_DROME	Chromodomain-helicase-DNA-binding protein 1	18202396	Investigations of CHD1 function in transcription and development of Drosophila melanogaster.

Q95ST2	WLS_DROME	Protein wntless	18193037	Wingless secretion requires endosome-to-Golgi retrieval of Wntless/Evi/Sprinter by the retromer complex.

P09972	ALDOC_HUMAN	Fructose-bisphosphate aldolase C	11399750	Interaction between aldolase and vacuolar H+-ATPase: evidence for direct coupling of glycolysis to the ATP-hydrolyzing proton pump.

Q13003	GRIK3_HUMAN	Glutamate receptor, ionotropic kainate 3	7719709	Molecular characterization of the human EAA5 (GluR7) receptor: a high-affinity kainate receptor with novel potential RNA editing sites.

Q10434	CAPZA_SCHPO	F-actin-capping protein subunit alpha	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9ZPY0	DOF25_ARATH	Dof zinc finger protein DOF2.5	12084825	Mutations in the Dof zinc finger genes DAG2 and DAG1 influence with opposite effects the germination of Arabidopsis seeds.

Q70SY1	CR3L2_HUMAN	Cyclic AMP-responsive element-binding protein 3-like protein 2	17178827	BBF2H7, a novel transmembrane bZIP transcription factor, is a new type of endoplasmic reticulum stress transducer.

P32486	KRE6_YEAST	Beta-glucan synthesis-associated protein KRE6	12237851	Actin patch assembly proteins Las17p and Sla1p restrict cell wall growth to daughter cells and interact with cis-Golgi protein Kre6p.

O42956	YGM8_SCHPO	Uncharacterized protein C19G7.08c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P06326	HV107_HUMAN	Ig heavy chain V-I region Mot	3084950	Amino acid sequence of the variable region of heavy chain in immunoglobulin (Mot) having unusual papain cleavage sites.

Q06144	ORM2_YEAST	Protein ORM2	12093374	ORMDL proteins are a conserved new family of endoplasmic reticulum membrane proteins.

Q8R516	MIB2_MOUSE	E3 ubiquitin-protein ligase MIB2	15824097	Mind bomb-2 is an E3 ligase for Notch ligand.

P38689	KPR3_YEAST	Ribose-phosphate pyrophosphokinase 3	10212224	Genetic analysis and enzyme activity suggest the existence of more than one minimal functional unit capable of synthesizing phosphoribosyl pyrophosphate in Saccharomyces cerevisiae.

O14369	SCE3_SCHPO	Probable RNA-binding protein sce3	9254700	Sce3, a suppressor of the Schizosaccharomyces pombe septation mutant cdc11, encodes a putative RNA-binding protein.

Q09725	MIS4_SCHPO	Sister chromatid cohesion protein mis4	9808627	Faithful anaphase is ensured by Mis4, a sister chromatid cohesion molecule required in S phase and not destroyed in G1 phase.

Q8WTY4	CPIN1_MOUSE	Anamorsin	16957168	Subcellular localization of CIAPIN1.

Q9Y4K3	TRAF6_HUMAN	TNF receptor-associated factor 6	12140561	Distinct molecular mechanism for initiating TRAF6 signalling.

O43516	WIPF1_HUMAN	WAS/WASL-interacting protein family member 1	9405671	WIP, a protein associated with Wiskott-Aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cells.

Q14161	GIT2_HUMAN	ARF GTPase-activating protein GIT2	10896954	The GIT family of ADP-ribosylation factor GTPase-activating proteins. Functional diversity of GIT2 through alternative splicing.

O14896	IRF6_HUMAN	Interferon regulatory factor 6	16049006	Mammary serine protease inhibitor (Maspin) binds directly to interferon regulatory factor 6: identification of a novel serpin partnership.

P05423	RPC4_HUMAN	DNA-directed RNA polymerase III subunit RPC4	19631370	RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway.

Q501D8	C79B3_ARATH	Tryptophan N-hydroxylase 2	10681464	Arabidopsis cytochrome P450s that catalyze the first step of tryptophan-dependent indole-3-acetic acid biosynthesis.

Q9ERU9	RBP2_MOUSE	E3 SUMO-protein ligase RanBP2	16332688	Parkin ubiquitinates and promotes the degradation of RanBP2.

Q5A477	GMT_CANAL	GDP-mannose transporter	11741841	Molecular and phenotypic analysis of CaVRG4, encoding an essential Golgi apparatus GDP-mannose transporter.

O74801	RL4P_SCHPO	60S ribosomal protein yml6, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P35799	DPY2_CAEEL	Cuticle collagen dpy-2	8241567	Molecular and genetic analyses of the Caenorhabditis elegans dpy-2 and dpy-10 collagen genes: a variety of molecular alterations affect organismal morphology.

A1Y9I9	TOMT_MOUSE	Transmembrane O-methyltransferase	18794526	A catechol-O-methyltransferase that is essential for auditory function in mice and humans.

P51136	GSK3_DICDI	Glycogen synthase kinase-3	9784196	An assay for glycogen synthase kinase 3 (GSK-3) for use in crude cell extracts.

Q12303	YPS3_YEAST	Aspartic proteinase yapsin-3	16087741	Yapsins are a family of aspartyl proteases required for cell wall integrity in Saccharomyces cerevisiae.

Q6PE84	STML3_MOUSE	Stomatin-like protein 3	12122055	Stomatin-related olfactory protein, SRO, specifically expressed in the murine olfactory sensory neurons.

Q39071	CCA21_ARATH	Cyclin-A2-1	17012601	Increased level of polyploidy1, a conserved repressor of CYCLINA2 transcription, controls endoreduplication in Arabidopsis.

P55135	RUMA_ECOLI	23S rRNA (uracil-5-)-methyltransferase rumA	11779873	Characterization of the 23 S ribosomal RNA m5U1939 methyltransferase from Escherichia coli.

P53879	RHO5_YEAST	GTP-binding protein RHO5	11591390	Functional characterization of the Bag7, Lrg1 and Rgd2 RhoGAP proteins from Saccharomyces cerevisiae.

Q09756	HXK1_SCHPO	Hexokinase-1	8549830	Schizosaccharomyces pombe possesses an unusual and a conventional hexokinase: biochemical and molecular characterization of both hexokinases.

Q07500	NDH2_YEAST	External NADH-ubiquinone oxidoreductase 2, mitochondrial	11502169	Yeast mitochondrial dehydrogenases are associated in a supramolecular complex.

P12760	NMU_RAT	Neuromedin-U	15635449	Identification of neuromedin S and its possible role in the mammalian circadian oscillator system.

Q55CS7	MPL1_DICDI	MAP kinase phosphatase with leucine-rich repeats protein 1	18408056	MPL1, a novel phosphatase with leucine-rich repeats, is essential for proper ERK2 phosphorylation and cell motility.

Q90ZE2	ZN703_DANRE	Zinc finger protein 703	14550789	Nlz belongs to a family of zinc-finger-containing repressors and controls segmental gene expression in the zebrafish hindbrain.

P49790	NU153_HUMAN	Nuclear pore complex protein Nup153	8110839	Sequence analysis of a cDNA encoding a human nuclear pore complex protein, hnup153.

Q9Y586	MB212_HUMAN	Protein mab-21-like 2	10556287	Two murine and human homologs of mab-21, a cell fate determination gene involved in Caenorhabditis elegans neural development.

P38011	GBLP_YEAST	Guanine nucleotide-binding protein subunit beta-like protein	15340087	Yeast Asc1p and mammalian RACK1 are functionally orthologous core 40S ribosomal proteins that repress gene expression.

P38445	AVR2B_RAT	Activin receptor type-2B	7916681	Expression of type II activin receptor genes in the male and female reproductive tissues of the rat.

Q13387	JIP2_HUMAN	C-Jun-amino-terminal kinase-interacting protein 2	10756100	cDNA cloning and mapping of a novel islet-brain/JNK interacting protein.

Q60611	SATB1_MOUSE	DNA-binding protein SATB1	15851481	Nuclear matrix binding regulates SATB1-mediated transcriptional repression.

P40507	AIR1_YEAST	Protein AIR1	10896665	Novel RING finger proteins, Air1p and Air2p, interact with Hmt1p and inhibit the arginine methylation of Npl3p.

Q04886	SOX8_MOUSE	Transcription factor SOX-8	10684944	Cloning and characterisation of the Sry-related transcription factor gene Sox8.

P80067	CATC_RAT	Dipeptidyl peptidase 1	11602245	Tetrameric dipeptidyl peptidase I directs substrate specificity by use of the residual pro-part domain.

P52299	NCBP2_XENLA	Nuclear cap-binding protein subunit 2	7651522	A cap-binding protein complex mediating U snRNA export.

Q08956	YIG1_YEAST	Protein YIG1	16358322	The YIG1 (YPL201c) encoded protein is involved in regulating anaerobic glycerol metabolism in Saccharomyces cerevisiae.

Q92993	KAT5_HUMAN	Histone acetyltransferase KAT5	10966108	Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis.

P49598	P2C37_ARATH	Protein phosphatase 2C 37	16339800	ABA-hypersensitive germination3 encodes a protein phosphatase 2C (AtPP2CA) that strongly regulates abscisic acid signaling during germination among Arabidopsis protein phosphatase 2Cs.

Q9SMZ4	AASS_ARATH	Alpha-aminoadipic semialdehyde synthase	12393892	The activity of the Arabidopsis bifunctional lysine-ketoglutarate reductase/saccharopine dehydrogenase enzyme of lysine catabolism is regulated by functional interaction between its two enzyme domains.

Q5B7Z3	PLYE_EMENI	Pectate lyase E	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

P40554	URM1_YEAST	Ubiquitin-related modifier 1	18664566	Thio-modification of yeast cytosolic tRNA requires a ubiquitin- related system that resembles bacterial sulfur transfer systems.

Q9P0J0	NDUAD_HUMAN	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	12867595	The cell death regulator GRIM-19 is an inhibitor of signal transducer and activator of transcription 3.

Q7LBR1	CHM1B_HUMAN	Charged multivesicular body protein 1b	17928862	ESCRT-III recognition by VPS4 ATPases.

Q9UKM7	MA1B1_HUMAN	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase	10521544	Cloning and expression of a specific human alpha1,2-mannosidase that trims Man9GlcNAc2 to Man8GlcNAc2 isomer B during N-glycan biosynthesis.

Q54UT2	DGK_DICDI	Deoxyguanosine kinase	17448496	Dictyostelium discoideum salvages purine deoxyribonucleosides by highly specific bacterial-like deoxyribonucleoside kinases.

P84694	SC83_TITCA	Toxin Tc83	15025998	Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

Q01094	E2F1_HUMAN	Transcription factor E2F1	16360038	Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release.

Q9BYG4	PAR6G_HUMAN	Partitioning defective 6 homolog gamma	11260256	Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42 to atypical protein kinase C.

O75106	AOC2_HUMAN	Retina-specific copper amine oxidase	9119395	Human retina-specific amine oxidase (RAO): cDNA cloning, tissue expression, and chromosomal mapping.

O16844	COS_DROME	Kinesin-like protein costa	9244298	Costal2, a novel kinesin-related protein in the Hedgehog signaling pathway.

Q54JY7	STX7A_DICDI	Syntaxin-7A	12175335	Syntaxin 7, syntaxin 8, Vti1 and VAMP7 (vesicle-associated membrane protein 7) form an active SNARE complex for early macropinocytic compartment fusion in Dictyostelium discoideum.

O43082	RR14C_SCHPO	Ribosomal RNA-processing protein 14-C	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O13828	DCP2_SCHPO	mRNA decapping complex subunit 2	15671491	Decapping reaction of mRNA requires Dcp1 in fission yeast: its characterization in different species from yeast to human.

P54843	MAF_MOUSE	Transcription factor Maf	14512017	Absence of transcription factor c-maf causes abnormal terminal differentiation of hypertrophic chondrocytes during endochondral bone development.

Q06168	SFH1_YEAST	Chromatin structure-remodeling complex subunit SFH1	10619019	Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains.

O94446	ESA1_SCHPO	Histone acetyltransferase mst1	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

Q3E785	SDHF1_YEAST	Succinate dehydrogenase assembly factor 1 homolog, mitochondrial	19465911	SDHAF1, encoding a LYR complex-II specific assembly factor, is mutated in SDH-defective infantile leukoencephalopathy.

P14712	PHYA_ARATH	Phytochrome A	8400877	Arabidopsis HY8 locus encodes phytochrome A.

P27216	ANX13_HUMAN	Annexin A13	1530946	A strategy for isolation of cDNAs encoding proteins affecting human intestinal epithelial cell growth and differentiation: characterization of a novel gut-specific N-myristoylated annexin.

O74832	PT127_SCHPO	mRNA degradation protein pet127, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P36888	FLT3_HUMAN	FL cytokine receptor	8394751	Human FLT3/FLK2 gene: cDNA cloning and expression in hematopoietic cells.

Q5GFD5	HS3S6_MOUSE	Heparan sulfate glucosamine 3-O-sulfotransferase 6	15303968	Characterization of heparan sulphate 3-O-sulphotransferase isoform 6 and its role in assisting the entry of herpes simplex virus type 1.

Q4U0Y4	NPL1A_XENLA	Nucleosome assembly protein 1-like 1-A	14550533	Xenopus nucleosome assembly protein becomes tissue-restricted during development and can alter the expression of specific genes.

O43674	NDUB5_HUMAN	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial	9425316	Identification and primary structure of five human NADH-ubiquinone oxidoreductase subunits.

Q12933	TRAF2_HUMAN	TNF receptor-associated factor 2	9418902	4-1BB and Ox40 are members of a tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor kappaB.

Q9GZP9	DERL2_HUMAN	Derlin-2	16449189	Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation.

P42747	UBC14_ARATH	Ubiquitin-conjugating enzyme E2 14	16339806	Genome analysis and functional characterization of the E2 and RING- type E3 ligase ubiquitination enzymes of Arabidopsis.

Q10943	ARF12_CAEEL	ADP-ribosylation factor 1-like 2	15716356	Involvement of the actin cytoskeleton and homotypic membrane fusion in ER dynamics in Caenorhabditis elegans.

P40384	REC12_SCHPO	Meiotic recombination protein rec12	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UBC3	DNM3B_HUMAN	DNA (cytosine-5)-methyltransferase 3B	16357870	The Polycomb group protein EZH2 directly controls DNA methylation.

O57460	TLL1_DANRE	Dorsal-ventral patterning tolloid-like protein 1	9395394	Cleavage of the BMP-4 antagonist chordin by zebrafish Tolloid.

Q91898	HESXB_XENLA	Homeobox expressed in ES cells 1-B	8582293	The homeobox-containing gene XANF-1 may control development of the Spemann organizer.

P0A769	MNTH_ECOLI	Manganese transport protein mntH	10712688	Identification of the Escherichia coli K-12 Nramp orthologue (MntH) as a selective divalent metal ion transporter.

P53632	PAP2_YEAST	Poly(A) RNA polymerase protein 2	16260630	Trf4 and Trf5 proteins of Saccharomyces cerevisiae exhibit poly(A) RNA polymerase activity but no DNA polymerase activity.

P05060	SCG1_HUMAN	Secretogranin-1	3608978	The primary structure of human secretogranin I (chromogranin B): comparison with chromogranin A reveals homologous terminal domains and a large intervening variable region.

O94346	ARGJ_SCHPO	Arginine biosynthesis bifunctional protein ArgJ, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P53978	EF3B_YEAST	Elongation factor 3B	9544245	Identification and kinetic analysis of a functional homolog of elongation factor 3, YEF3 in Saccharomyces cerevisiae.

Q9W497	GR05A_DROME	Gustatory receptor for trehalose	10710312	Candidate taste receptors in Drosophila.

O80765	PANK1_ARATH	Pantothenate kinase 1	12860978	4'-phosphopantetheine and coenzyme A biosynthesis in plants.

Q9NST1	PLPL3_HUMAN	Patatin-like phospholipase domain-containing protein 3	15364929	Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities.

Q9H3M7	TXNIP_HUMAN	Thioredoxin-interacting protein	20068034	The ubiquitin ligase itch regulates apoptosis by targeting thioredoxin-interacting protein for ubiquitin-dependent degradation.

P32970	CD70_HUMAN	CD70 antigen	8120384	The cloning of CD70 and its identification as the ligand for CD27.

Q9UMR7	CLC4A_HUMAN	C-type lectin domain family 4 member A	10438934	APCs express DCIR, a novel C-type lectin surface receptor containing an immunoreceptor tyrosine-based inhibitory motif.

P25105	PTAFR_HUMAN	Platelet-activating factor receptor	1281995	Molecular cloning and characterization of the platelet-activating factor receptor gene expressed in the human heart.

P27633	TBP_XENLA	TATA-box-binding protein	1641350	Conserved structural motifs within the N-terminal domain of TFIID tau from Xenopus, mouse and human.

P12004	PCNA_HUMAN	Proliferating cell nuclear antigen	16510448	Functional roles of p12, the fourth subunit of human DNA polymerase delta.

Q04110	ECM11_YEAST	Protein ECM11	11678331	Ecm11 is located in the cell nucleus throughout mitosis.

Q9FQ20	SCC12_ARATH	Sister chromatid cohesion 1 protein 2	11410371	Cloning and characterization of two Arabidopsis genes that belong to the RAD21/REC8 family of chromosome cohesin proteins.

P34078	LTV1_YEAST	Protein LTV1	16732272	A conserved GTPase-containing complex is required for intracellular sorting of the general amino-acid permease in yeast.

Q553Y0	P2XC_DICDI	P2X receptor C	19833731	Functional characterization of intracellular Dictyostelium discoideum P2X receptors.

P06652	MPIP_SCHPO	M-phase inducer phosphatase	3955656	cdc25+ functions as an inducer in the mitotic control of fission yeast.

O44437	SMD3_DROME	Small nuclear ribonucleoprotein Sm D3	9488472	The Drosophila gene for antizyme requires ribosomal frameshifting for expression and contains an intronic gene for snRNP Sm D3 on the opposite strand.

O88572	LRP6_MOUSE	Low-density lipoprotein receptor-related protein 6	19857465	Neucrin is a novel neural-specific secreted antagonist to canonical Wnt signaling.

Q7TMK9	HNRPQ_MOUSE	Heterogeneous nuclear ribonucleoprotein Q	10734137	SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms.

Q8WRC7	CCAP_MANSE	Cardioactive peptide	3925062	Insect cardioactive peptides. I. Distribution and molecular characteristics of two cardioacceleratory peptides in the tobacco hawkmoth, Manduca sexta.

O94413	KPR3_SCHPO	Ribose-phosphate pyrophosphokinase 3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O43303	CE110_HUMAN	Centrosomal protein of 110 kDa	17719545	Cep97 and CP110 suppress a cilia assembly program.

Q9V2V6	PSA1_HALVD	Proteasome subunit alpha 1	10482525	Halophilic 20S proteasomes of the archaeon Haloferax volcanii: purification, characterization, and gene sequence analysis.

P34909	NOT4_YEAST	General negative regulator of transcription subunit 4	8164670	The yeast MOT2 gene encodes a putative zinc finger protein that serves as a global negative regulator affecting expression of several categories of genes, including mating-pheromone-responsive genes.

P40427	EXD_DROME	Homeobox protein extradenticle	9346235	Nuclear translocation of extradenticle requires homothorax, which encodes an extradenticle-related homeodomain protein.

Q06510	TAZ1_YEAST	Lysophosphatidylcholine acyltransferase	14562095	Global analysis of protein localization in budding yeast.

P70280	VAMP7_MOUSE	Vesicle-associated membrane protein 7	15470500	TI-VAMP/VAMP7 is required for optimal phagocytosis of opsonised particles in macrophages.

P0A8N5	SYK2_ECOLI	Lysyl-tRNA synthetase, heat inducible	10913247	Active site of lysyl-tRNA synthetase: structural studies of the adenylation reaction.

P0AEU7	SKP_ECOLI	Chaperone protein skp	9914480	Affinity of the periplasmic chaperone Skp of Escherichia coli for phospholipids, lipopolysaccharides and non-native outer membrane proteins. Role of Skp in the biogenesis of outer membrane protein.

Q8W104	FBL17_ARATH	F-box/LRR-repeat protein 17	18948957	Control of plant germline proliferation by SCF(FBL17) degradation of cell cycle inhibitors.

Q7Z7H5	TMED4_HUMAN	Transmembrane emp24 domain-containing protein 4	12761501	Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.

P32914	SPT4_YEAST	Transcription elongation factor SPT4	15057281	Functional roles for evolutionarily conserved Spt4p at centromeres and heterochromatin in Saccharomyces cerevisiae.

Q99798	ACON_HUMAN	Aconitate hydratase, mitochondrial	9630632	Characterization of the human mitochondrial aconitase gene (ACO2).

Q7KRY7	LAP4_DROME	Protein lap4	10688207	Localization of apical epithelial determinants by the basolateral PDZ protein Scribble.

P02317	STP1_RAT	Spermatid nuclear transition protein 1	2820847	Isolation of a cDNA clone for transition protein 1 (TP1), a major chromosomal protein of mammalian spermatids.

Q9QZR5	HIPK2_MOUSE	Homeodomain-interacting protein kinase 2	9748262	Homeodomain-interacting protein kinases, a novel family of co- repressors for homeodomain transcription factors.

O22785	PR19B_ARATH	Pre-mRNA-processing factor 19 homolog 2	19629177	Two Prp19-like U-box proteins in the MOS4-associated complex play redundant roles in plant innate immunity.

Q961D9	BCL9_DROME	Protein BCL9 homolog	11955446	Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex.

P80162	CXCL6_HUMAN	C-X-C motif chemokine 6	9164944	Cloning and characterization of the human granulocyte chemotactic protein-2 gene.

Q9QZX8	SO1B2_RAT	Solute carrier organic anion transporter family member 1B2	10500057	Molecular characterization and functional regulation of a novel rat liver-specific organic anion transporter rlst-1.

Q38824	IAA6_ARATH	Auxin-responsive protein IAA6	7658471	The PS-IAA4/5-like family of early auxin-inducible mRNAs in Arabidopsis thaliana.

O22043	GGPP6_ARATH	Geranylgeranyl pyrophosphate synthase 6, mitochondrial	9349257	Geranylgeranyl pyrophosphate synthase encoded by the newly isolated gene GGPS6 from Arabidopsis thaliana is localized in mitochondria.

Q55FP0	PHG1A_DICDI	Putative phagocytic receptor 1a	16367873	Specific host genes required for the killing of Klebsiella bacteria by phagocytes.

Q9UM01	YLAT1_HUMAN	Y+L amino acid transporter 1	9878049	Amino acid transport of y+L-type by heterodimers of 4F2hc/CD98 and members of the glycoprotein-associated amino acid transporter family.

P01581	IFNG_RAT	Interferon gamma	3924594	Cloning and expression of the chromosomal immune interferon gene of the rat.

P48561	TRF5_YEAST	Poly(A) RNA polymerase protein 1	16260630	Trf4 and Trf5 proteins of Saccharomyces cerevisiae exhibit poly(A) RNA polymerase activity but no DNA polymerase activity.

P54843	MAF_MOUSE	Transcription factor Maf	10403649	The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines.

Q9IAV3	HHEX_DANRE	Hematopoietically-expressed homeobox protein hhex	14568547	Zebrafish hhex, nk2.1a, and pax2.1 regulate thyroid growth and differentiation downstream of Nodal-dependent transcription factors.

Q04368	CSI1_YEAST	Cop9 signalosome-interactor 1	12186635	Conservation of the COP9/signalosome in budding yeast.

Q12263	GIN4_YEAST	Serine/threonine-protein kinase GIN4	9813093	Role of the yeast Gin4p protein kinase in septin assembly and the relationship between septin assembly and septin function.

Q12882	DPYD_HUMAN	Dihydropyrimidine dehydrogenase [NADP+]	8083224	cDNA cloning and chromosome mapping of human dihydropyrimidine dehydrogenase, an enzyme associated with 5-fluorouracil toxicity and congenital thymine uraciluria.

P47040	BTN1_YEAST	Protein BTN1	14660799	A role in vacuolar arginine transport for yeast Btn1p and for human CLN3, the protein defective in Batten disease.

Q9LSP9	CTL2_ARATH	Chitinase-like protein 2	20056293	Mutation of the chitinase-like protein-encoding AtCTL2 gene enhances lignin accumulation in dark-grown Arabidopsis seedlings.

Q55AP1	GRLA_DICDI	Metabotropic glutamate receptor-like protein A	17950724	A GPCR involved in post aggregation events in Dictyostelium discoideum.

Q9EP51	V1R50_MOUSE	Vomeronasal type-1 receptor 50	11116090	Sequence diversity and genomic organization of vomeronasal receptor genes in the mouse.

O96625	ARPC4_DICDI	Actin-related protein 2/3 complex subunit 4	17296313	Vectors for expression of proteins with single or combinatorial fluorescent protein and tandem affinity purification tags in Dictyostelium.

P70689	CXB6_MOUSE	Gap junction beta-6 protein	19864490	Consortin, a trans-Golgi network cargo receptor for the plasma membrane targeting and recycling of connexins.

Q15011	HERP1_HUMAN	Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein	10708769	The novel MMS-inducible gene Mif1/KIAA0025 is a target of the unfolded protein response pathway.

Q22909	HM30_CAEEL	Homeobox protein ceh-30	18056428	The C. elegans protein CEH-30 protects male-specific neurons from apoptosis independently of the Bcl-2 homolog CED-9.

Q9XTG7	AKT2_CAEEL	Serine/threonine-protein kinase akt-2	9716402	Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor.

O96690	PDF_DROME	Protein PDF	15356209	The neuropeptide pigment-dispersing factor coordinates pacemaker interactions in the Drosophila circadian system.

Q9BZP6	CHIA_HUMAN	Acidic mammalian chitinase	11085997	Identification of a novel acidic mammalian chitinase distinct from chitotriosidase.

O94242	SYDM_SCHPO	Aspartyl-tRNA synthetase, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9LZR5	HDT3_ARATH	Histone deacetylase HDT3	12694598	Repression of gene expression by Arabidopsis HD2 histone deacetylases.

Q9VUF8	CP314_DROME	Ecdysone 20-monooxygenase	14610274	Shade is the Drosophila P450 enzyme that mediates the hydroxylation of ecdysone to the steroid insect molting hormone 20- hydroxyecdysone.

Q62141	SIN3B_MOUSE	Paired amphipathic helix protein Sin3b	16787967	Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway?

P31946	1433B_HUMAN	14-3-3 protein beta/alpha	17974916	Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control.

P36627	BYR3_SCHPO	Cellular nucleic acid-binding protein homolog	1515675	A gene encoding a protein with seven zinc finger domains acts on the sexual differentiation pathways of Schizosaccharomyces pombe.

Q9LPI7	NAC12_ARATH	NAC domain-containing protein 12	17237351	NAC transcription factors, NST1 and NST3, are key regulators of the formation of secondary walls in woody tissues of Arabidopsis.

P25171	RCC1_DROME	Regulator of chromosome condensation	2022188	The maternally expressed Drosophila gene encoding the chromatin- binding protein BJ1 is a homolog of the vertebrate gene Regulator of Chromatin Condensation, RCC1.

P93022	ARFG_ARATH	Auxin response factor 7	10810148	The NPH4 locus encodes the auxin response factor ARF7, a conditional regulator of differential growth in aerial Arabidopsis tissue.

Q09725	MIS4_SCHPO	Sister chromatid cohesion protein mis4	16682348	A screen for cohesion mutants uncovers ssl3, the fission yeast counterpart of the cohesin loading factor scc4.

Q86CR8	ATG8_DICDI	Autophagy-related protein 8	14736886	Dictyostelium macroautophagy mutants vary in the severity of their developmental defects.

O43684	BUB3_HUMAN	Mitotic checkpoint protein BUB3	18199686	The human spindle assembly checkpoint protein Bub3 is required for the establishment of efficient kinetochore-microtubule attachments.

P05067	A4_HUMAN	Amyloid beta A4 protein	19901339	RAGE-mediated signaling contributes to intraneuronal transport of amyloid-{beta} and neuronal dysfunction.

Q8IW19	APLF_HUMAN	Aprataxin and PNK-like factor	17396150	A novel human AP endonuclease with conserved zinc-finger-like motifs involved in DNA strand break responses.

O55060	TPMT_MOUSE	Thiopurine S-methyltransferase	9539138	Molecular cloning and functional characterization of the cDNA encoding the murine thiopurine S-methyltransferase (TPMT).

Q9UQE7	SMC3_HUMAN	Structural maintenance of chromosomes protein 3	9506951	Complex formation of SMAP/KAP3, a KIF3A/B ATPase motor-associated protein, with a human chromosome-associated polypeptide.

Q9H330	CI005_HUMAN	Transmembrane protein C9orf5	10564813	Cloning, genomic organization and expression of a putative human transmembrane protein related to the Caenorhabditis elegans M01F1.4 gene.

Q9EP53	TSC1_MOUSE	Hamartin	11438694	A germ-line Tsc1 mutation causes tumor development and embryonic lethality that are similar, but not identical to, those caused by Tsc2 mutation in mice.

P0ACL9	PDHR_ECOLI	Pyruvate dehydrogenase complex repressor	8262214	A mutation causing constitutive synthesis of the pyruvate dehydrogenase complex in Escherichia coli is located within the pdhR gene.

Q9BXU7	UBP26_HUMAN	Ubiquitin carboxyl-terminal hydrolase 26	20501646	The deubiquitinating enzyme USP26 is a regulator of androgen receptor signaling.

P25349	YCP4_YEAST	Flavoprotein-like protein YCP4	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Q9USS6	PPA4_SCHPO	Probable acid phosphatase SPBC4.06	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q54ZW0	PHG1B_DICDI	Putative phagocytic receptor 1b	12857872	Synergistic control of cellular adhesion by transmembrane 9 proteins.

Q9ERE4	GOLP3_RAT	Golgi phosphoprotein 3	16236792	GMx33 associates with the trans-Golgi matrix in a dynamic manner and sorts within tubules exiting the Golgi.

Q9BYG5	PAR6B_HUMAN	Partitioning defective 6 homolog beta	11260256	Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42 to atypical protein kinase C.

Q13315	ATM_HUMAN	Serine-protein kinase ATM	11375976	Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks.

Q12676	FOLD_YEAST	Folylpolyglutamate synthase	14562095	Global analysis of protein localization in budding yeast.

Q96QT6	PHF12_HUMAN	PHD finger protein 12	11390640	Pf1, a novel PHD zinc finger protein that links the TLE corepressor to the mSin3A-histone deacetylase complex.

Q9Z301	PER2_RAT	Period circadian protein homolog 2	15094047	Indication of circadian oscillations in the rat pancreas.

Q8NFJ9	BBS1_HUMAN	Bardet-Biedl syndrome 1 protein	17574030	A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis.

Q60520	SIN3A_MOUSE	Paired amphipathic helix protein Sin3a	12198165	The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription.

P07196	NFL_HUMAN	Neurofilament light polypeptide	12432080	Effects of Charcot-Marie-Tooth-linked mutations of the neurofilament light subunit on intermediate filament formation.

Q07478	SUB2_YEAST	ATP-dependent RNA helicase SUB2	11156602	Identification and characterization of yUAP/Sub2p, a yeast homolog of the essential human pre-mRNA splicing factor hUAP56.

Q925J9	MED1_MOUSE	Mediator of RNA polymerase II transcription subunit 1	9325263	Isolation and characterization of PBP, a protein that interacts with peroxisome proliferator-activated receptor.

Q96AZ6	ISG20_HUMAN	Interferon-stimulated gene 20 kDa protein	11401564	The human interferon- and estrogen-regulated ISG20/HEM45 gene product degrades single-stranded RNA and DNA in vitro.

Q9JKF6	PVRL1_MOUSE	Poliovirus receptor-related protein 1	11090177	Striking similarity of murine nectin-1alpha to human nectin-1alpha (HveC) in sequence and activity as a glycoprotein D receptor for alphaherpesvirus entry.

Q9H0P0	5NT3_HUMAN	Cytosolic 5'-nucleotidase 3	12930399	Molecular characterization of six unrelated Italian patients affected by pyrimidine 5'-nucleotidase deficiency.

Q9UTC0	ZYM1_SCHPO	Metallothionein zym1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q09604	VAB15_CAEEL	Homeobox protein vab-15	11333230	Genes regulating touch cell development in Caenorhabditis elegans.

Q9NZH6	IL1F7_HUMAN	Interleukin-1 family member 7	10744718	Identification and initial characterization of four novel members of the interleukin-1 family.

Q80XX4	MSTN1_RAT	Musculoskeletal embryonic nuclear protein 1	14718386	Molecular cloning and characterization of Mustang, a novel nuclear protein expressed during skeletal development and regeneration.

Q8S8N9	GOGC1_ARATH	Golgin candidate 1	18182439	Localization and domain characterization of Arabidopsis golgin candidates.

Q9ZPX5	DHSA2_ARATH	Succinate dehydrogenase [ubiquinone] flavoprotein subunit 2, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q15797	SMAD1_HUMAN	Mothers against decapentaplegic homolog 1	8663601	Serine phosphorylation, chromosomal localization, and transforming growth factor-beta signal transduction by human bsp-1.

O60238	BNI3L_HUMAN	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like	10381623	A novel adenovirus E1B19K-binding protein B5 inhibits apoptosis induced by Nip3 by forming a heterodimer through the C-terminal hydrophobic region.

P39394	SYME_ECOLI	Toxic protein symE	10760155	Identification of additional genes belonging to the LexA regulon in Escherichia coli.

P27138	TFDB_RALEJ	2,4-dichlorophenol 6-monooxygenase	2185214	Organization and sequence analysis of the 2,4-dichlorophenol hydroxylase and dichlorocatechol oxidative operons of plasmid pJP4.

Q03390	VPS60_YEAST	Vacuolar protein-sorting-associated protein 60	14562095	Global analysis of protein localization in budding yeast.

B5LUQ6	FALX5_LITFA	Preprofallaxidin-5	18803332	The fallaxidin peptides from the skin secretion of the eastern dwarf tree frog Litoria fallax. Sequence determination by positive and negative ion electrospray mass spectrometry: antimicrobial activity and cDNA cloning of the fallaxidins.

P42900	SLS1_YEAST	Sigma-like sequence protein 1, mitochondrial	8917313	SLS1, a new Saccharomyces cerevisiae gene involved in mitochondrial metabolism, isolated as a syntheticlethal in association with an SSM4 deletion.

P79832	ARNT_ONCMY	Aryl hydrocarbon receptor nuclear translocator	8940073	Isolation and expression of cDNAs from rainbow trout (Oncorhynchus mykiss) that encode two novel basic helix-loop-helix/PER-ARNT-SIM (bHLH/PAS) proteins with distinct functions in the presence of the aryl hydrocarbon receptor. Evidence for alternative mRNA splicing and dominant negative activity in the bHLH/PAS family.

O74539	MAK3_SCHPO	Peroxide stress-activated histidine kinase mak3	11179424	Peroxide sensors for the fission yeast stress-activated mitogen- activated protein kinase pathway.

P81925	AB27_CYPCA	27 kDa antibacterial protein	8797847	Characterization and ion channel activities of novel antibacterial proteins from the skin mucosa of carp (Cyprinus carpio).

Q9UDY8	MALT1_HUMAN	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	14695475	Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO.

Q9Y738	MIS12_SCHPO	Centromere protein mis12	15369671	Mis16 and Mis18 are required for CENP-A loading and histone deacetylation at centromeres.

Q9FJ13	COBL9_ARATH	COBRA-like protein 9	12376623	The COBRA family of putative GPI-anchored proteins in Arabidopsis. A new fellowship in expansion.

O94670	YBWC_SCHPO	Uncharacterized protein C651.12c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O15254	ACOX3_HUMAN	Peroxisomal acyl-coenzyme A oxidase 3	9271077	Evidence for the existence of a pristanoyl-CoA oxidase gene in man.

Q80ZA0	ITL1B_MOUSE	Intelectin-1b	15048991	Proteomic analysis of mouse jejunal epithelium and its response to infection with the intestinal nematode, Trichinella spiralis.

P06899	H2B1J_HUMAN	Histone H2B type 1-J	6647026	The primary structure and expression of four cloned human histone genes.

O77203	PIAA_DICDI	Protein pianissimo A	17659086	High-throughput analysis of spatio-temporal dynamics in Dictyostelium.

P83581	HS74L_RAT	Heat shock 70 kDa protein 4L	10806408	Germ cell-specific heat shock protein 105 binds to p53 in a temperature-sensitive manner in rat testis.

P40589	WNT4_DROME	Protein Wnt-4	7867502	DWnt-4, a novel Drosophila Wnt gene acts downstream of homeotic complex genes in the visceral mesoderm.

Q08930	YP191_YEAST	Uncharacterized protein YPL191C	14562095	Global analysis of protein localization in budding yeast.

P41318	LST8_YEAST	Target of rapamycin complex subunit LST8	16002396	Molecular organization of target of rapamycin complex 2.

O95343	SIX3_HUMAN	Homeobox protein SIX3	10369266	Mutations in the homeodomain of the human SIX3 gene cause holoprosencephaly.

Q15633	TRBP2_HUMAN	RISC-loading complex subunit TARBP2	11641396	Organization of the human tarbp2 gene reveals two promoters that are repressed in an astrocytic cell line.

Q01538	MYT1_HUMAN	Myelin transcription factor 1	1280325	Novel member of the zinc finger superfamily: a C2-HC finger that recognizes a glia-specific gene.

P07834	CDC4_YEAST	Cell division control protein 4	9346238	F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex.

Q94AA9	XGD1_ARATH	Xylogalacturonan beta-1,3-xylosyltransferase	18460606	Identification of a xylogalacturonan xylosyltransferase involved in pectin biosynthesis in Arabidopsis.

Q09739	MCP7_SCHPO	Meiotic coiled-coil protein 7	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q93WC9	IPT3_ARATH	Adenylate isopentenyltransferase 3, chloroplastic	15998742	Agrobacterium tumefaciens increases cytokinin production in plastids by modifying the biosynthetic pathway in the host plant.

Q968Z6	PSIA_DICDI	Protein psiA	15367206	A gene encoding, prespore-cell-inducing factor in Dictyostelium discoideum.

Q9VKK1	EDC4_DROME	Enhancer of mRNA-decapping protein 4 homolog	18755833	The C-terminal region of Ge-1 presents conserved structural features required for P-body localization.

P09467	F16P1_HUMAN	Fructose-1,6-bisphosphatase 1	8387495	Isolation of a human liver fructose-1,6-bisphosphatase cDNA and expression of the protein in Escherichia coli. Role of Asp-118 and Asp-121 in catalysis.

Q05948	YL225_YEAST	Uncharacterized SVF1-like protein YLR225C	14562095	Global analysis of protein localization in budding yeast.

Q39253	CAX1_ARATH	Vacuolar cation/proton exchanger 1	14630965	Mutations in the Ca2+/H+ transporter CAX1 increase CBF/DREB1 expression and the cold-acclimation response in Arabidopsis.

P19634	SL9A1_HUMAN	Sodium/hydrogen exchanger 1	12809501	The Na+/H+ exchanger cytoplasmic tail: structure, function, and interactions with tescalcin.

Q9UTR9	YLP2_SCHPO	Uncharacterized WD repeat-containing protein C1006.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P0A6B7	ISCS_ECOLI	Cysteine desulfurase	10739946	Kinetic and mutational studies of three NifS homologs from Escherichia coli: mechanistic difference between L-cysteine desulfurase and L-selenocysteine lyase reactions.

P23254	TKT1_YEAST	Transketolase 1	8226984	Yeast TKL1 gene encodes a transketolase that is required for efficient glycolysis and biosynthesis of aromatic amino acids.

Q0VKZ3	ALKB1_ALCBS	Alkane 1-monooxygenase 1	14871210	Characterization of two alkane hydroxylase genes from the marine hydrocarbonoclastic bacterium Alcanivorax borkumensis.

Q9C8X2	SUC5_ARATH	Sucrose transport protein SUC5	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q14BI7	TDRD9_MOUSE	Putative ATP-dependent RNA helicase TDRD9	20011505	Cytoplasmic compartmentalization of the fetal piRNA pathway in mice.

Q96BK5	PINX1_HUMAN	PIN2/TERF1-interacting telomerase inhibitor 1	19393617	PinX1 is recruited to the mitotic chromosome periphery by nucleolin and facilitates chromosome congression.

Q96T76	MMS19_HUMAN	MMS19 nucleotide excision repair protein homolog	11071939	Cloning of a human homolog of the yeast nucleotide excision repair gene MMS19 and interaction with transcription repair factor TFIIH via the XPB and XPD helicases.

Q93XX5	Y5713_ARATH	PI-PLC X domain-containing protein At5g67130	14517339	Proteomic analysis of glycosylphosphatidylinositol-anchored membrane proteins.

Q29974	2B1G_HUMAN	HLA class II histocompatibility antigen, DRB1-16 beta chain	3129499	Molecular studies of a rare DR2/LD-5a/DQw3 HLA class II haplotype. Multiple genetic mechanisms in the generation of polymorphic HLA class II genes.

P08621	RU17_HUMAN	U1 small nuclear ribonucleoprotein 70 kDa	2467746	A common RNA recognition motif identified within a defined U1 RNA binding domain of the 70K U1 snRNP protein.

Q9FZ95	PUP3_ARATH	Purine permease 3	10662864	A new family of high-affinity transporters for adenine, cytosine, and purine derivatives in Arabidopsis.

Q39163	TGA5_ARATH	Transcription factor TGA5	8252072	Isolation and characterization of two related Arabidopsis ocs-element bZIP binding proteins.

Q99287	SEY1_YEAST	Protein SEY1	12427979	Function of a plant stress-induced gene, HVA22. Synthetic enhancement screen with its yeast homolog reveals its role in vesicular traffic.

Q99743	NPAS2_HUMAN	Neuronal PAS domain-containing protein 2	9079689	Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway.

Q61850	FOXC2_MOUSE	Forkhead box protein C2	8325367	MFH-1, a new member of the fork head domain family, is expressed in developing mesenchyme.

O04017	NAC98_ARATH	Protein CUP-SHAPED COTYLEDON 2	10079219	Shoot apical meristem and cotyledon formation during Arabidopsis embryogenesis: interaction among the CUP-SHAPED COTYLEDON and SHOOT MERISTEMLESS genes.

O35095	NCDN_RAT	Neurochondrin	10521593	Norbin, a neurite-outgrowth-related protein, is a cytosolic protein localized in the somatodendritic region of neurons and distributed prominently in dendritic outgrowth in Purkinje cells.

Q23921	PKIA_DICDI	Protein pkiA	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

Q9P7P9	YLY6_SCHPO	Uncharacterized isomerase C186.06	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Y7M1	YGK4_SCHPO	Putative 2-hydroxyacyl-CoA lyase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P40033	RSM18_YEAST	37S ribosomal protein RSM18, mitochondrial	11278769	Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues.

O74782	YGBA_SCHPO	Universal stress protein A family protein C25B2.10	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q99JE6	PLCB3_RAT	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3	8454637	Cloning, sequencing, purification, and Gq-dependent activation of phospholipase C-beta 3.

Q03557	GATH_YEAST	Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial	18667535	Genetic and structural analysis of Hmg2p-induced endoplasmic reticulum remodeling in Saccharomyces cerevisiae.

P52653	TBP1_ENTHI	TATA-box-binding protein 1	20026212	Entamoeba histolytica: a unicellular organism containing two active genes encoding for members of the TBP family.

Q95Q17	MED7_CAEEL	Mediator of RNA polymerase II transcription subunit 7	10611325	Caenorhabditis elegans mediator complexes are required for developmental-specific transcriptional activation.

O15706	VACA_DICDI	Vacuolin-A	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q9WTX6	CUL1_MOUSE	Cullin-1	12140560	E3 ubiquitin ligase that recognizes sugar chains.

Q9P246	STIM2_HUMAN	Stromal interaction molecule 2	17905723	STIM2 protein mediates distinct store-dependent and store-independent modes of CRAC channel activation.

O59726	YHX6_SCHPO	Uncharacterized MFS-type transporter C3E7.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9VVT2	INDY1_DROME	Protein I'm not dead yet	12391301	Functional characterization and immunolocalization of the transporter encoded by the life-extending gene Indy.

Q12098	SLX4_YEAST	Structure-specific endonuclease subunit SLX4	18471978	Microarray-based genetic screen defines SAW1, a gene required for Rad1/Rad10-dependent processing of recombination intermediates.

O57429	UBP2_CHICK	Ubiquitin carboxyl-terminal hydrolase 2	9325273	Molecular cloning of a novel ubiquitin-specific protease, UBP41, with isopeptidase activity in chick skeletal muscle.

Q12008	PMG2_YEAST	Phosphoglycerate mutase 2	9544241	Investigation of two yeast genes encoding putative isoenzymes of phosphoglycerate mutase.

P48029	SC6A8_HUMAN	Sodium- and chloride-dependent creatine transporter 1	8661155	The genomic organization of a human creatine transporter (CRTR) gene located in Xq28.

P38273	CCZ1_YEAST	Vacuolar fusion protein CCZ1	12364329	The Ccz1-Mon1 protein complex is required for the late step of multiple vacuole delivery pathways.

Q9ZT50	RHA2A_ARATH	E3 ubiquitin-protein ligase RHA2A	15644464	Functional analysis of the RING-type ubiquitin ligase family of Arabidopsis.

P07347	ARD1_YEAST	N-terminal acetyltransferase A complex catalytic subunit ARD1	1600941	ARD1 and NAT1 proteins form a complex that has N-terminal acetyltransferase activity.

Q13813	SPTA2_HUMAN	Spectrin alpha chain, brain	2307671	Generation of diversity in nonerythroid spectrins. Multiple polypeptides are predicted by sequence analysis of cDNAs encompassing the coding region of human nonerythroid alpha-spectrin.

Q8INF0	GCY8E_DROME	Soluble guanylate cyclase 88E	15159437	Preliminary characterization of two atypical soluble guanylyl cyclases in the central and peripheral nervous system of Drosophila melanogaster.

P70340	SMAD1_MOUSE	Mothers against decapentaplegic homolog 1	16801560	Nanog binds to Smad1 and blocks bone morphogenetic protein-induced differentiation of embryonic stem cells.

Q3E731	COX19_YEAST	Cytochrome c oxidase assembly protein COX19	12171940	Characterization of COX19, a widely distributed gene required for expression of mitochondrial cytochrome oxidase.

P11101	STP2_RAT	Nuclear transition protein 2	8954887	Cloning of cDNA encoding rat spermatidal protein TP2 and expression in Escherichia coli.

P13689	ABP1_MAIZE	Auxin-binding protein 1	12065401	Crystal structure of auxin-binding protein 1 in complex with auxin.

Q8I948	ACN1_ACAGO	Acanthoscurrin-1	12818635	Acanthoscurrin: a novel glycine-rich antimicrobial peptide constitutively expressed in the hemocytes of the spider Acanthoscurria gomesiana.

Q94527	NFKB1_DROME	Nuclear factor NF-kappa-B p110 subunit	11269501	Activation of the Drosophila NF-kappaB factor Relish by rapid endoproteolytic cleavage.

P04689	TBA2_SCHPO	Tubulin alpha-2 chain	9658169	Identification of novel temperature-sensitive lethal alleles in essential beta-tubulin and nonessential alpha 2-tubulin genes as fission yeast polarity mutants.

P49281	NRAM2_HUMAN	Natural resistance-associated macrophage protein 2	15459009	Identification of a human mutation of DMT1 in a patient with microcytic anemia and iron overload.

O96623	ARPC2_DICDI	Actin-related protein 2/3 complex subunit 2	17296313	Vectors for expression of proteins with single or combinatorial fluorescent protein and tandem affinity purification tags in Dictyostelium.

Q9D358	PPAC_MOUSE	Low molecular weight phosphotyrosine protein phosphatase	9824304	Cloning of murine low molecular weight phosphotyrosine protein phosphatase cDNA: identification of a new isoform.

P10072	HKR1_HUMAN	Krueppel-related zinc finger protein 1	2850480	The GLI-Kruppel family of human genes.

Q9UJ71	CLC4K_HUMAN	C-type lectin domain family 4 member K	10661407	Langerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules.

O08679	MARK2_RAT	Serine/threonine-protein kinase MARK2	9108484	MARK - a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption.

P46662	MERL_MOUSE	Merlin	20181838	The tumor suppressor merlin is required for cell cycle exit, terminal differentiation, and cell polarity in the developing murine lens.

O60934	NBN_HUMAN	Nibrin	19683501	SOSS complexes participate in the maintenance of genomic stability.

O88419	B4GT6_RAT	Beta-1,4-galactosyltransferase 6	9593693	Purification, cDNA cloning, and expression of UDP-Gal: glucosylceramide beta-1,4-galactosyltransferase from rat brain.

P25116	PAR1_HUMAN	Proteinase-activated receptor 1	1672265	Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation.

Q8K0S5	R4RL1_MOUSE	Reticulon-4 receptor-like 1	14664809	Two novel mammalian nogo receptor homologs differentially expressed in the central and peripheral nervous systems.

Q9M020	LRKA2_ARATH	Lectin-domain containing receptor kinase A4.2	18987212	The Arabidopsis a4 subfamily of lectin receptor kinases negatively regulates abscisic acid response in seed germination.

O14512	SOCS7_HUMAN	Suppressor of cytokine signaling 7	17803907	Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7.

O74737	RID1_SCHPO	GTPase-binding protein rid1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q62949	CORT_RAT	Cortistatin	8622767	A cortical neuropeptide with neuronal depressant and sleep-modulating properties.

Q04771	ACVR1_HUMAN	Activin receptor type-1	16642017	A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva.

Q13268	DHRS2_HUMAN	Dehydrogenase/reductase SDR family member 2	7556196	A nuclear protein, synthesized in growth-arrested human hepatoblastoma cells, is a novel member of the short-chain alcohol dehydrogenase family.

Q9LKF9	CPSF2_ARATH	Cleavage and polyadenylation specificity factor subunit 2	12602868	An interaction between an Arabidopsis poly(A) polymerase and a homologue of the 100 kDa subunit of CPSF.

Q6EU39	MADS6_ORYSJ	MADS-box transcription factor 6	12395189	Ovule-specific MADS-box proteins have conserved protein-protein interactions in monocot and dicot plants.

P41833	IME4_YEAST	N6-adenosine-methyltransferase IME4	12384598	Induction of sporulation in Saccharomyces cerevisiae leads to the formation of N6-methyladenosine in mRNA: a potential mechanism for the activity of the IME4 gene.

Q9QWJ9	NRP1_RAT	Neuropilin-1	9288754	Neuropilin is a semaphorin III receptor.

P53921	YNM2_YEAST	Putative mitochondrial ribosomal protein YNL122C	17054397	Assessing systems properties of yeast mitochondria through an interaction map of the organelle.

P61962	DCAF7_HUMAN	DDB1- and CUL4-associated factor 7	16949367	A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1.

Q04400	ADCY5_RAT	Adenylate cyclase type 5	1409703	Two members of a widely expressed subfamily of hormone-stimulated adenylyl cyclases.

Q96G23	LASS2_HUMAN	LAG1 longevity assurance homolog 2	11543633	Cloning, mapping, and characterization of a human homologue of the yeast longevity assurance gene LAG1.

O43303	CE110_HUMAN	Centrosomal protein of 110 kDa	16760425	CP110 cooperates with two calcium-binding proteins to regulate cytokinesis and genome stability.

P50531	RAD17_SCHPO	Checkpoint protein rad17	8846774	Fission yeast rad17: a homologue of budding yeast RAD24 that shares regions of sequence similarity with DNA polymerase accessory proteins.

Q08622	FMP38_YEAST	Mitochondrial protein FMP38	14562095	Global analysis of protein localization in budding yeast.

P0A6W3	MRAY_ECOLI	Phospho-N-acetylmuramoyl-pentapeptide-transferase	1846850	The Escherichia coli mraY gene encoding UDP-N-acetylmuramoyl- pentapeptide: undecaprenyl-phosphate phospho-N-acetylmuramoyl- pentapeptide transferase.

Q08219	YO048_YEAST	Uncharacterized membrane protein YOL048C	14562095	Global analysis of protein localization in budding yeast.

Q9V4M2	WECH_DROME	Protein wech	8725239	Identification of immune system and response genes, and novel mutations causing melanotic tumor formation in Drosophila melanogaster.

Q9HC62	SENP2_HUMAN	Sentrin-specific protease 2	15296745	A basis for SUMO protease specificity provided by analysis of human Senp2 and a Senp2-SUMO complex.

Q96SB3	NEB2_HUMAN	Neurabin-2	11278317	The human tumor suppressor ARF interacts with spinophilin/neurabin II, a type 1 protein-phosphatase-binding protein.

P49893	WN11B_XENLA	Protein Wnt-11b	18927149	Wnt5a and Wnt11 interact in a maternal Dkk1-regulated fashion to activate both canonical and non-canonical signaling in Xenopus axis formation.

P61830	H3_YEAST	Histone H3	11742990	The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4.

Q6PCX7	RGMA_MOUSE	Repulsive guidance molecule A	17472960	Repulsive guidance molecule RGMa alters utilization of bone morphogenetic protein (BMP) type II receptors by BMP2 and BMP4.

Q8N149	LIRA2_HUMAN	Leukocyte immunoglobulin-like receptor subfamily A member 2	9548455	A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules.

P51843	NR0B1_HUMAN	Nuclear receptor subfamily 0 group B member 1	16709599	Dosage-sensitive sex reversal adrenal hypoplasia congenita critical region on the X chromosome, gene 1 (DAX1) (NR0B1) and small heterodimer partner (SHP) (NR0B2) form homodimers individually, as well as DAX1-SHP heterodimers.

Q9SKT3	SCAM1_ARATH	Secretory carrier-associated membrane protein 1	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q99795	GPA33_HUMAN	Cell surface A33 antigen	9012807	The human A33 antigen is a transmembrane glycoprotein and a novel member of the immunoglobulin superfamily.

P30402	PYRX_YEAST	Orotate phosphoribosyltransferase 2	2182197	Cloning and sequencing of URA10, a second gene encoding orotate phosphoribosyl transferase in Saccharomyces cerevisiae.

Q9BYD1	RM13_HUMAN	39S ribosomal protein L13, mitochondrial	11279069	Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria.

Q02256	PVH1_YEAST	Tyrosine-protein phosphatase YVH1	1334559	A yeast protein phosphatase related to the vaccinia virus VH1 phosphatase is induced by nitrogen starvation.

O04046	GGPP2_ARATH	Geranylgeranyl pyrophosphate synthase 2	9150607	Cloning and functional expression of a novel geranylgeranyl pyrophosphate synthase gene from Arabidopsis thaliana in Escherichia coli.

O14013	RRN5_SCHPO	RNA polymerase I-specific transcription initiation factor rrn5	12490702	Characterization of the fission yeast ribosomal DNA binding factor: components share homology with upstream activating factor and with SWI/SNF subunits.

P22543	VPS34_YEAST	Phosphatidylinositol 3-kinase VPS34	7989323	Vps34p required for yeast vacuolar protein sorting is a multiple specificity kinase that exhibits both protein kinase and phosphatidylinositol-specific PI 3-kinase activities.

O43174	CP26A_HUMAN	Cytochrome P450 26A1	9228017	cDNA cloning of human retinoic acid-metabolizing enzyme (hP450RAI) identifies a novel family of cytochromes P450.

P27657	LIPP_RAT	Pancreatic triacylglycerol lipase	8203536	Rat pancreatic lipase and two related proteins: enzymatic properties and mRNA expression during development.

Q9FN52	MAM3_ARATH	Methylthioalkylmalate synthase 3, chloroplastic	12432038	Isolation and expression analysis of the isopropylmalate synthase gene family of Arabidopsis thaliana.

Q09180	MAP2_SCHPO	P-factor	8314086	The fission yeast mating pheromone P-factor: its molecular structure, gene structure, and ability to induce gene expression and G1 arrest in the mating partner.

P34709	TRA2_CAEEL	Sex-determining transformer protein 2	1498366	tra-2 encodes a membrane protein and may mediate cell communication in the Caenorhabditis elegans sex determination pathway.

P04040	CATA_HUMAN	Catalase	11134921	Structure of tetragonal crystals of human erythrocyte catalase.

O62090	PRY1_CAEEL	Axin-like protein pry-1	12023307	The axin-like protein PRY-1 is a negative regulator of a canonical Wnt pathway in C. elegans.

O04479	LBD6_ARATH	LOB domain-containing protein 6	11311158	The ASYMMETRIC LEAVES2 gene of Arabidopsis thaliana regulates formation of a symmetric lamina, establishment of venation and repression of meristem-related homeobox genes in leaves.

Q9WVK0	ATRAP_MOUSE	Type-1 angiotensin II receptor-associated protein	10358057	Cloning and characterization of ATRAP, a novel protein that interacts with the angiotensin II type 1 receptor.

Q9EPA7	NMNA1_MOUSE	Nicotinamide mononucleotide adenylyltransferase 1	16914673	Stimulation of nicotinamide adenine dinucleotide biosynthetic pathways delays axonal degeneration after axotomy.

P29067	ARRB2_RAT	Beta-arrestin-2	1517224	Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family.

P49588	SYAC_HUMAN	Alanyl-tRNA synthetase, cytoplasmic	7654687	Human alanyl-tRNA synthetase: conservation in evolution of catalytic core and microhelix recognition.

O00187	MASP2_HUMAN	Mannan-binding lectin serine protease 2	9087411	A second serine protease associated with mannan-binding lectin that activates complement.

P0AFE0	NUOJ_ECOLI	NADH-quinone oxidoreductase subunit J	15919996	Global topology analysis of the Escherichia coli inner membrane proteome.

Q9Z1T5	DEAF1_MOUSE	Deformed epidermal autoregulatory factor 1 homolog	19668219	Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes.

P00790	PEPA_HUMAN	Pepsin A	6300126	Primary structure of human pepsinogen gene.

Q9Y2W2	WBP11_HUMAN	WW domain-binding protein 11	19592703	Structure and function of the two tandem WW domains of the pre-mRNA splicing factor FBP21 (formin-binding protein 21).

P15625	SYFA_YEAST	Phenylalanyl-tRNA synthetase alpha chain	3049607	Structure and expression of the genes encoding the alpha and beta subunits of yeast phenylalanyl-tRNA synthetase.

Q9ZPE4	FBW2_ARATH	F-box protein FBW2	12795696	Protein interaction analysis of SCF ubiquitin E3 ligase subunits from Arabidopsis.

P48556	PSMD8_HUMAN	26S proteasome non-ATPase regulatory subunit 8	7621825	Nin1p, a regulatory subunit of the 26S proteasome, is necessary for activation of Cdc28p kinase of Saccharomyces cerevisiae.

Q8NHZ8	CDC26_HUMAN	Anaphase-promoting complex subunit CDC26	16364912	Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C.

P36046	MIA40_YEAST	Mitochondrial intermembrane space import and assembly protein 40	15359280	Essential role of Mia40 in import and assembly of mitochondrial intermembrane space proteins.

Q99550	MPP9_HUMAN	M-phase phosphoprotein 9	8885239	Identification of novel M phase phosphoproteins by expression cloning.

Q8BHP7	OLM2A_MOUSE	Olfactomedin-like protein 2A	15836428	Identification and characterization of photomedins: novel olfactomedin-domain-containing proteins with chondroitin sulphate-E- binding activity.

P24100	CDKA1_ARATH	Cyclin-dependent kinase A-1	14706832	In vivo interaction between CDKA and eIF4A: a possible mechanism linking translation and cell proliferation.

Q9NJG9	SUZ12_DROME	Polycomb protein Su(z)12	12408864	Histone methyltransferase activity of a Drosophila Polycomb group repressor complex.

P63005	LIS1_MOUSE	Platelet-activating factor acetylhydrolase IB subunit alpha	16107726	Complete loss of Ndel1 results in neuronal migration defects and early embryonic lethality.

P04075	ALDOA_HUMAN	Fructose-bisphosphate aldolase A	14766013	Human aldolase A natural mutants: relationship between flexibility of the C-terminal region and enzyme function.

Q9BXL7	CAR11_HUMAN	Caspase recruitment domain-containing protein 11	11278692	CARD11 and CARD14 are novel caspase recruitment domain (CARD)/membrane-associated guanylate kinase (MAGUK) family members that interact with Bcl10 and activate NF-kappaB.

P10997	IAPP_HUMAN	Islet amyloid polypeptide	2608057	Human islet amyloid polypeptide gene: complete nucleotide sequence, chromosomal localization, and evolutionary history.

Q9HB21	PKHA1_HUMAN	Pleckstrin homology domain-containing family A member 1	11802782	Evidence that the tandem-pleckstrin-homology-domain-containing protein TAPP1 interacts with Ptd(3,4)P2 and the multi-PDZ-domain- containing protein MUPP1 in vivo.

Q8K214	SCMH1_MOUSE	Polycomb protein SCMH1	10653359	A novel member of murine polycomb-group proteins, Sex comb on midleg homolog protein, is highly conserved, and interacts with RAE28/mph1 in vitro.

Q06144	ORM2_YEAST	Protein ORM2	20182505	Orm family proteins mediate sphingolipid homeostasis.

P40541	SCC3_YEAST	Cohesin subunit SCC3	11864574	Eco1 is a novel acetyltransferase that can acetylate proteins involved in cohesion.

O14423	CBH1_SCHPO	CENP-B homolog protein 1	9237993	Purification and characterization of a CENP-B homologue protein that binds to the centromeric K-type repeat DNA of Schizosaccharomyces pombe.

Q9BZR6	RTN4R_HUMAN	Reticulon-4 receptor	11201742	Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration.

P32580	SUV3_YEAST	ATP-dependent RNA helicase SUV3, mitochondrial	12426313	The yeast mitochondrial degradosome. Its composition, interplay between RNA helicase and RNase activities and the role in mitochondrial RNA metabolism.

Q923B6	STEA4_MOUSE	Metalloreductase STEAP4	11443137	Tumor necrosis factor-alpha-induced adipose-related protein (TIARP), a cell-surface protein that is highly induced by tumor necrosis factor-alpha and adipose conversion.

P11217	PYGM_HUMAN	Glycogen phosphorylase, muscle form	9633816	Molecular diagnosis of McArdle disease: revised genomic structure of the myophosphorylase gene and identification of a novel mutation.

P16410	CTLA4_HUMAN	Cytotoxic T-lymphocyte protein 4	3220103	Human Ig superfamily CTLA-4 gene: chromosomal localization and identity of protein sequence between murine and human CTLA-4 cytoplasmic domains.

P24329	THTR_RAT	Thiosulfate sulfurtransferase	2018478	Molecular cloning, sequencing and characterization of cDNA to rat liver rhodanese, a thiosulphate sulphurtransferase.

P53695	EXO1_SCHPO	Exodeoxyribonuclease 1	1737756	A DNA exonuclease induced during meiosis of Schizosaccharomyces pombe.

P40995	SCD1_SCHPO	Rho guanine nucleotide exchange factor scd1	12972551	Gef1p and Scd1p, the Two GDP-GTP exchange factors for Cdc42p, form a ring structure that shrinks during cytokinesis in Schizosaccharomyces pombe.

P37275	ZEB1_HUMAN	Zinc finger E-box-binding homeobox 1	8138542	Transcription factors positively and negatively regulating the Na,K- ATPase alpha 1 subunit gene.

Q62805	GALR1_RAT	Galanin receptor type 1	8750821	Cloning and characterization of the rat GALR1 galanin receptor from Rin14B insulinoma cells.

P09669	COX6C_HUMAN	Cytochrome c oxidase subunit 6C	2849755	Nucleotide sequence of cDNA encoding human cytochrome c oxidase subunit VIc.

P46684	ZIC1_MOUSE	Zinc finger protein ZIC 1	7931345	A novel zinc finger protein, zic, is involved in neurogenesis, especially in the cell lineage of cerebellar granule cells.

Q06685	VIP1_YEAST	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase	17412958	A conserved family of enzymes that phosphorylate inositol hexakisphosphate.

P60520	GBRL2_HUMAN	Gamma-aminobutyric acid receptor-associated protein-like 2	11414770	Cloning, expression patterns, and chromosome localization of three human and two mouse homologues of GABA(A) receptor-associated protein.

Q07457	BRE1_YEAST	E3 ubiquitin-protein ligase BRE1	12535539	Bre1, an E3 ubiquitin ligase required for recruitment and substrate selection of Rad6 at a promoter.

P19429	TNNI3_HUMAN	Troponin I, cardiac muscle	12531876	Idiopathic restrictive cardiomyopathy is part of the clinical expression of cardiac troponin I mutations.

P49448	DHE4_HUMAN	Glutamate dehydrogenase 2, mitochondrial	8207021	Novel human glutamate dehydrogenase expressed in neural and testicular tissues and encoded by an X-linked intronless gene.

P16671	CD36_HUMAN	Platelet glycoprotein 4	7518447	Structural organization of the gene for human CD36 glycoprotein.

P40021	ZRG8_YEAST	Zinc-regulated protein 8	15972461	A role for the Saccharomyces cerevisiae regulation of Ace2 and polarized morphogenesis signaling network in cell integrity.

Q05466	HAT4_ARATH	Homeobox-leucine zipper protein HAT4	8449400	The HAT4 gene of Arabidopsis encodes a developmental regulator.

P70278	STRA8_MOUSE	Stimulated by retinoic acid gene 8 protein	17115059	In germ cells of mouse embryonic ovaries, the decision to enter meiosis precedes premeiotic DNA replication.

Q3ZCQ8	TIM50_HUMAN	Mitochondrial import inner membrane translocase subunit TIM50	16008839	Tim50a, a nuclear isoform of the mitochondrial Tim50, interacts with proteins involved in snRNP biogenesis.

P24257	WNT1_DANRE	Protein Wnt-1	15659486	Wnt1 regulates neurogenesis and mediates lateral inhibition of boundary cell specification in the zebrafish hindbrain.

Q9D593	VATE2_MOUSE	V-type proton ATPase subunit E 2	11872743	A proton pump ATPase with testis-specific E1-subunit isoform required for acrosome acidification.

P16949	STMN1_HUMAN	Stathmin	16548883	Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection.

O95861	BPNT1_HUMAN	3'(2'),5'-bisphosphate nucleotidase 1	10224133	Cloning and characterization of a mammalian lithium-sensitive bisphosphate 3'-nucleotidase inhibited by inositol 1,4-bisphosphate.

Q6WKW9	HMGX4_XENLA	HMG box-containing protein 4	12875653	Negative regulation of Wnt signalling by HMG2L1, a novel NLK-binding protein.

Q9UUB5	MIS13_SCHPO	Kinetochore protein mis13	16079914	Molecular analysis of kinetochore architecture in fission yeast.

Q6P3A8	ODBB_MOUSE	2-oxoisovalerate dehydrogenase subunit beta, mitochondrial	8268236	Molecular cloning and analysis of the expression of the E1 beta subunit of branched chain alpha-ketoacid dehydrogenase in mice.

Q05533	INM2_YEAST	Inositol monophosphatase 2	12593845	Yeast inositol mono- and trisphosphate levels are modulated by inositol monophosphatase activity and nutrients.

Q8VYR7	BOR1_ARATH	Boron transporter 1	9390427	bor1-1, an Arabidopsis thaliana mutant that requires a high level of boron.

P00488	F13A_HUMAN	Coagulation factor XIII A chain	2877457	Characterization of cDNA coding for human factor XIIIa.

O88597	BECN1_MOUSE	Beclin-1	9765397	Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein.

P86041	SVN_SCYVA	Scytovirin	17269926	Carbohydrate microarrays as tools in HIV glycobiology.

Q8VD75	HIP1_MOUSE	Huntingtin-interacting protein 1	11577110	Clathrin- and AP-2-binding sites in HIP1 uncover a general assembly role for endocytic accessory proteins.

P68036	UB2L3_HUMAN	Ubiquitin-conjugating enzyme E2 L3	18946090	Novel control of S phase of the cell cycle by ubiquitin-conjugating enzyme H7.

O14682	ENC1_HUMAN	Ectoderm-neural cortex protein 1	9566959	NRP/B, a novel nuclear matrix protein, associates with p110(RB) and is involved in neuronal differentiation.

Q13882	PTK6_HUMAN	Protein-tyrosine kinase 6	8036022	Cloning and characterisation of cDNAs encoding a novel non-receptor tyrosine kinase, brk, expressed in human breast tumours.

Q8NBP7	PCSK9_HUMAN	Proprotein convertase subtilisin/kexin type 9	14622975	Functional characterization of Narc 1, a novel proteinase related to proteinase K.

O97394	SDK_DROME	Protein sidekick	9310325	The sidekick gene, a member of the immunoglobulin superfamily, is required for pattern formation in the Drosophila eye.

Q9HAW4	CLSPN_HUMAN	Claspin	15226314	Human claspin is a ring-shaped DNA-binding protein with high affinity to branched DNA structures.

Q6A2H4	IL10_CHICK	Interleukin-10	17045659	Changes in immune-related gene expression and intestinal lymphocyte subpopulations following Eimeria maxima infection of chickens.

O43312	MTSS1_HUMAN	Metastasis suppressor protein 1	12082544	MIM, a potential metastasis suppressor gene in bladder cancer.

Q6UVJ0	SAS6_HUMAN	Spindle assembly abnormal protein 6 homolog	14654843	Proteomic characterization of the human centrosome by protein correlation profiling.

Q9C7R6	PUB17_ARATH	U-box domain-containing protein 17	16531496	The E3 ubiquitin ligase activity of arabidopsis PLANT U-BOX17 and its functional tobacco homolog ACRE276 are required for cell death and defense.

Q92878	RAD50_HUMAN	DNA repair protein RAD50	9705271	Nuclease activities in a complex of human recombination and DNA repair factors Rad50, Mre11, and p95.

Q9HDV6	MOR2_SCHPO	Cell polarity protein mor2	12234926	Fission yeast Mor2/Cps12, a protein similar to Drosophila Furry, is essential for cell morphogenesis and its mutation induces Wee1- dependent G2 delay.

Q6L9W6	B4GN3_HUMAN	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2	12966086	Molecular cloning and characterization of a novel human beta 1,4-N- acetylgalactosaminyltransferase, beta 4GalNAc-T3, responsible for the synthesis of N,N'-diacetyllactosediamine, galNAc beta 1-4GlcNAc.

O93827	MPG1_CANAL	Mannose-1-phosphate guanyltransferase	9782489	Cloning and sequencing of the Candida albicans homologue of SRB1/PSA1/VIG9, the essential gene encoding GDP-mannose pyrophosphorylase in Saccharomyces cerevisiae.

Q9UUG9	TSC2_SCHPO	Tuberous sclerosis 2 protein homolog	14718525	Tsc1+ and tsc2+ regulate arginine uptake and metabolism in Schizosaccharomyces pombe.

Q03921	DOP1_YEAST	Protein dopey	14562095	Global analysis of protein localization in budding yeast.

Q61790	LAG3_MOUSE	Lymphocyte activation gene 3 protein	8602528	Independent modes of natural killing distinguished in mice lacking Lag3.

Q12440	APC2_YEAST	Anaphase-promoting complex subunit 2	9469814	Mass spectrometric analysis of the anaphase-promoting complex from yeast: identification of a subunit related to cullins.

Q10423	CCE1_SCHPO	Cruciform cutting endonuclease 1, mitochondrial	9343409	Characterization of a Holliday junction-resolving enzyme from Schizosaccharomyces pombe.

Q10067	ORC3_SCHPO	Origin recognition complex subunit 3	11850415	Purification and characterization of the Schizosaccharomyces pombe origin recognition complex: interaction with origin DNA and Cdc18 protein.

P0ADG4	SUHB_ECOLI	Inositol-1-monophosphatase	8002619	Inositol monophosphatase activity from the Escherichia coli suhB gene product.

Q868Z9	PPN_DROME	Papilin	3320045	Papilin: a Drosophila proteoglycan-like sulfated glycoprotein from basement membranes.

Q1JQ73	ELV1A_XENLA	ELAV-like protein 1-A	8873767	Cytoplasmic polyadenylation of activin receptor mRNA and the control of pattern formation in Xenopus development.

P42759	ERD10_ARATH	Dehydrin ERD10	8069491	Characterization of two cDNAs (ERD10 and ERD14) corresponding to genes that respond rapidly to dehydration stress in Arabidopsis thaliana.

Q9SFU6	CALS9_ARATH	Callose synthase 9	18315544	Dual function of Arabidopsis glucan synthase-like genes GSL8 and GSL10 in male gametophyte development and plant growth.

Q9FUG4	XPB2_ARATH	DNA repair helicase XPB2	15656976	Functional XPB/RAD25 redundancy in Arabidopsis genome: characterization of AtXPB2 and expression analysis.

Q9VAW5	LARP_DROME	La-related protein	10878606	dlarp, a new candidate Hox target in Drosophila whose orthologue in mouse is expressed at sites of epithelium/mesenchymal interactions.

Q9LKZ3	RBR1_ARATH	Retinoblastoma-related protein 1	16361519	Cell type-specific role of the retinoblastoma/E2F pathway during Arabidopsis leaf development.

Q91Z63	TRI63_RAT	E3 ubiquitin-protein ligase TRIM63	11679633	Identification of ubiquitin ligases required for skeletal muscle atrophy.

Q9NZ94	NLGN3_HUMAN	Neuroligin-3	12669065	Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism.

P07737	PROF1_HUMAN	Profilin-1	17914456	Structural basis for the recruitment of profilin-actin complexes during filament elongation by Ena/VASP.

Q53GT1	KLH22_HUMAN	Kelch-like protein 22	19995937	The Cul3-KLHL21 E3 ubiquitin ligase targets aurora B to midzone microtubules in anaphase and is required for cytokinesis.

P35131	UBC8_ARATH	Ubiquitin-conjugating enzyme E2 8	8220461	Homologs of the essential ubiquitin conjugating enzymes UBC1, 4, and 5 in yeast are encoded by a multigene family in Arabidopsis thaliana.

Q9NS56	TOPRS_HUMAN	E3 ubiquitin-protein ligase Topors	15735665	Topors, a p53 and topoisomerase I-binding RING finger protein, is a coactivator of p53 in growth suppression induced by DNA damage.

P51668	UB2D1_HUMAN	Ubiquitin-conjugating enzyme E2 D1	18359941	Members of the E2D (UbcH5) family mediate the ubiquitination of the conserved cysteine of Pex5p, the peroxisomal import receptor.

Q04003	SAS4_YEAST	Something about silencing protein 4	12626510	Sas4 and Sas5 are required for the histone acetyltransferase activity of Sas2 in the SAS complex.

O14715	RGPD8_HUMAN	RANBP2-like and GRIP domain-containing protein 8	9480752	Identification of a novel Ran binding protein 2 related gene (RANBP2L1) and detection of a gene cluster on human chromosome 2q11- q12.

P18858	DNLI1_HUMAN	DNA ligase 1	2204063	Human DNA ligase I cDNA: cloning and functional expression in Saccharomyces cerevisiae.

Q79PF4	KAIC_SYNE7	Circadian clock protein kinase kaiC	10064581	Physical interactions among circadian clock proteins KaiA, KaiB and KaiC in cyanobacteria.

Q18223	FBSP1_CAEEL	F-box/SPRY domain-containing protein 1	15208641	An SCF-like ubiquitin ligase complex that controls presynaptic differentiation.

P49716	CEBPD_HUMAN	CCAAT/enhancer-binding protein delta	8314590	The human C/EBP delta (CRP3/CELF) gene: structure and chromosomal localization.

Q64692	SIA8D_MOUSE	CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase	8690732	Molecular cloning and characterization of a third type of N-glycan alpha 2,8-sialyltransferase from mouse lung.

Q15691	MARE1_HUMAN	Microtubule-associated protein RP/EB family member 1	10226031	The APC-associated protein EB1 associates with components of the dynactin complex and cytoplasmic dynein intermediate chain.

Q9H2X6	HIPK2_HUMAN	Homeodomain-interacting protein kinase 2	14678985	HIPK2 regulates transforming growth factor-beta-induced c-Jun NH(2)- terminal kinase activation and apoptosis in human hepatoma cells.

O89049	TRXR1_RAT	Thioredoxin reductase 1, cytoplasmic	10849437	Essential role of selenium in the catalytic activities of mammalian thioredoxin reductase revealed by characterization of recombinant enzymes with selenocysteine mutations.

Q8CHQ9	CMLO2_MOUSE	Probable N-acetyltransferase CML2	11397015	Overexpression of camello, a member of a novel protein family, reduces blastomere adhesion and inhibits gastrulation in Xenopus laevis.

Q62986	ESR2_RAT	Estrogen receptor beta	9600083	A novel isoform of rat estrogen receptor beta with 18 amino acid insertion in the ligand binding domain as a putative dominant negative regular of estrogen action.

P0ADS2	ZAPA_ECOLI	Cell division protein zapA	17428494	FtsZ polymer-bundling by the Escherichia coli ZapA orthologue, YgfE, involves a conformational change in bound GTP.

O42668	TPR1_SCHPO	Tetratricopeptide repeat protein 1	10471809	Tpr1, a Schizosaccharomyces pombe protein involved in potassium transport.

Q8RWG8	RBP1B_ARATH	Ran-binding protein 1 homolog b	9025305	Characterization of proteins that interact with the GTP-bound form of the regulatory GTPase Ran in Arabidopsis.

P49454	CENPF_HUMAN	Centromere protein F	17600710	Cenp-F links kinetochores to Ndel1/Nde1/Lis1/dynein microtubule motor complexes.

Q01853	TERA_MOUSE	Transitional endoplasmic reticulum ATPase	14988733	Structural basis of the interaction between the AAA ATPase p97/VCP and its adaptor protein p47.

P00747	PLMN_HUMAN	Plasminogen	1986355	Two types of abnormal genes for plasminogen in families with a predisposition for thrombosis.

Q06675	MCM21_YEAST	Central kinetochore subunit MCM21	14633972	Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes.

Q9Y463	DYR1B_HUMAN	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	14500717	Serine/threonine kinase Mirk/Dyrk1B is an inhibitor of epithelial cell migration and is negatively regulated by the Met adaptor Ran- binding protein M.

P84760	ALVOL_POLAE	Alveolarin	15165727	Alveolarin, a novel antifungal polypeptide from the wild mushroom Polyporus alveolaris.

Q9UTA7	YL8B_SCHPO	Uncharacterized transcriptional regulatory protein C25B8.11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P38339	RGD1_YEAST	RHO GTPase-activating protein RGD1	10590461	RGD1 genetically interacts with MID2 and SLG1, encoding two putative sensors for cell integrity signalling in Saccharomyces cerevisiae.

Q9S7T7	SCC11_ARATH	Sister chromatid cohesion 1 protein 1	10072401	Isolation and characterization of SYN1, a RAD21-like gene essential for meiosis in Arabidopsis.

P41223	BUD31_HUMAN	Protein BUD31 homolog	7841202	Characterization of edg-2, a human homologue of the Xenopus maternal transcript G10 from endothelial cells.

Q5KSL6	DGKK_HUMAN	Diacylglycerol kinase kappa	16210324	Identification and characterization of a novel human type II diacylglycerol kinase, DGK kappa.

Q60520	SIN3A_MOUSE	Paired amphipathic helix protein Sin3a	11882901	Ubiquitination-dependent cofactor exchange on LIM homeodomain transcription factors.

P92029	DNJ60_DROME	DnaJ-like protein 60	9372188	The DnaJ60 gene of Drosophila melanogaster encodes a new member of the DnaJ family of proteins.

Q960T2	SAP47_DROME	Synapse-associated protein of 47 kDa	7494462	The sap47 gene of Drosophila melanogaster codes for a novel conserved neuronal protein associated with synaptic terminals.

P40105	YRF12_YEAST	Y' element ATP-dependent helicase protein 1 copy 2	9837911	Y'-Help1, a DNA helicase encoded by the yeast subtelomeric Y' element, is induced in survivors defective for telomerase.

Q9Y294	ASF1A_HUMAN	Histone chaperone ASF1A	11897662	Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway.

Q08581	SLK19_YEAST	Kinetochore protein SLK19	10835382	The Saccharomyces cerevisiae centromere protein Slk19p is required for two successive divisions during meiosis.

Q13547	HDAC1_HUMAN	Histone deacetylase 1	19182791	Chfr is linked to tumour metastasis through the downregulation of HDAC1.

P19224	UD16_HUMAN	UDP-glucuronosyltransferase 1-6	3141926	Cloning and substrate specificity of a human phenol UDP- glucuronosyltransferase expressed in COS-7 cells.

P17096	HMGA1_HUMAN	High mobility group protein HMG-I/HMG-Y	10428834	Retinoid-dependent recruitment of a histone H1 displacement activity by retinoic acid receptor.

Q9USU5	GAS2_SCHPO	1,3-beta-glucanosyltransferase gas2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q07797	LG3BP_MOUSE	Galectin-3-binding protein	8341703	Cloning and characterization of cyclophilin C-associated protein: a candidate natural cellular ligand for cyclophilin C.

Q9XTQ6	TBH1_CAEEL	Tyramine beta-hydroxylase	15848803	Tyramine functions independently of octopamine in the Caenorhabditis elegans nervous system.

P34910	EVI2B_HUMAN	Protein EVI2B	1903357	cDNA sequence and genomic structure of EVI2B, a gene lying within an intron of the neurofibromatosis type 1 gene.

Q6QNY0	BL1S3_HUMAN	Biogenesis of lysosome-related organelles complex 1 subunit 3	16385460	A germline mutation in BLOC1S3/reduced pigmentation causes a novel variant of Hermansky-Pudlak syndrome (HPS8).

P30041	PRDX6_HUMAN	Peroxiredoxin-6	9497358	Characterization of a mammalian peroxiredoxin that contains one conserved cysteine.

P25054	APC_HUMAN	Adenomatous polyposis coli protein	16611247	Human scribble, a novel tumor suppressor identified as a target of high-risk HPV E6 for ubiquitin-mediated degradation, interacts with adenomatous polyposis coli.

P70310	NTR2_MOUSE	Neurotensin receptor type 2	8795617	Structure, functional expression, and cerebral localization of the levocabastine-sensitive neurotensin/neuromedin N receptor from mouse brain.

P12931	SRC_HUMAN	Proto-oncogene tyrosine-protein kinase Src	17525734	p140Cap protein suppresses tumour cell properties, regulating Csk and Src kinase activity.

O15205	UBD_HUMAN	Ubiquitin D	16495226	FAT10 plays a role in the regulation of chromosomal stability.

Q9QZS3	NUMB_MOUSE	Protein numb homolog	12410312	Progenitor cell maintenance requires numb and numblike during mouse neurogenesis.

Q12158	SCC1_YEAST	Sister chromatid cohesion protein 1	9335334	A direct link between sister chromatid cohesion and chromosome condensation revealed through the analysis of MCD1 in S. cerevisiae.

Q9Y812	CENPA_SCHPO	Histone H3-like centromeric protein cnp1	10864871	Requirement of Mis6 centromere connector for localizing a CENP-A-like protein in fission yeast.

Q8R4L0	SLAP2_MOUSE	Src-like-adapter 2	11891219	A novel Src homology 2 domain-containing molecule, Src-like adapter protein-2 (SLAP-2), which negatively regulates T cell receptor signaling.

Q12158	SCC1_YEAST	Sister chromatid cohesion protein 1	11864574	Eco1 is a novel acetyltransferase that can acetylate proteins involved in cohesion.

Q9BQA5	HINFP_HUMAN	Histone H4 transcription factor	14585971	Identification of HiNF-P, a key activator of cell cycle-controlled histone H4 genes at the onset of S phase.

Q91YD9	WASL_MOUSE	Neural Wiskott-Aldrich syndrome protein	11559594	Actin pedestal formation by enteropathogenic Escherichia coli and intracellular motility of Shigella flexneri are abolished in N-WASP- defective cells.

Q7TQA9	TR135_MOUSE	Taste receptor type 2 member 135	12734386	Evolutionary relationships of the Tas2r receptor gene families in mouse and human.

Q64359	CNGA4_RAT	Cyclic nucleotide-gated cation channel alpha-4	7522325	Heteromeric olfactory cyclic nucleotide-gated channels: a subunit that confers increased sensitivity to cAMP.

Q9Y2J2	E41L3_HUMAN	Band 4.1-like protein 3	12234973	Direct association of TSLC1 and DAL-1, two distinct tumor suppressor proteins in lung cancer.

Q08749	TIM18_YEAST	Mitochondrial import inner membrane translocase subunit TIM18	12637749	Protein insertion into the mitochondrial inner membrane by a twin- pore translocase.

O94506	RSM1_SCHPO	mRNA export factor rsm1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P14373	TRI27_HUMAN	Zinc finger protein RFP	15837424	Selective ablation of retinoblastoma protein function by the RET finger protein.

Q9Y2X9	ZN281_HUMAN	Zinc finger protein 281	10405178	Identification of human GC-box-binding zinc finger protein, a new Krueppel-like zinc finger protein, by the yeast one-hybrid screening with a GC-rich target sequence.

Q63053	ARC_RAT	Activity-regulated cytoskeleton-associated protein	7857651	Arc, a growth factor and activity-regulated gene, encodes a novel cytoskeleton-associated protein that is enriched in neuronal dendrites.

P57059	SIK1_HUMAN	Serine/threonine-protein kinase SIK1	14976552	LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1.

Q99706	KI2L4_HUMAN	Killer cell immunoglobulin-like receptor 2DL4	18604210	An essential function for beta-arrestin 2 in the inhibitory signaling of natural killer cells.

P46800	GBLP_DICDI	Guanine nucleotide-binding protein subunit beta-like protein	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q6PIZ9	TRAT1_HUMAN	T-cell receptor-associated transmembrane adapter 1	9687533	T cell receptor (TCR) interacting molecule (TRIM), a novel disulfide- linked dimer associated with the TCR-CD3-zeta complex, recruits intracellular signaling proteins to the plasma membrane.

Q15561	TEAD4_HUMAN	Transcriptional enhancer factor TEF-3	8921372	Cloning of human RTEF-1, a transcriptional enhancer factor-1-related gene preferentially expressed in skeletal muscle: evidence for an ancient multigene family.

P58462	FOXP1_MOUSE	Forkhead box protein P1	16819554	Foxp1 is an essential transcriptional regulator of B cell development.

Q8N729	NPW_HUMAN	Neuropeptide W	12401809	Identification of natural ligands for the orphan G protein-coupled receptors GPR7 and GPR8.

Q9Y5Y5	PEX16_HUMAN	Peroxisomal membrane protein PEX16	9922452	Peroxisome synthesis in the absence of preexisting peroxisomes.

Q99729	ROAA_HUMAN	Heterogeneous nuclear ribonucleoprotein A/B	8999813	Cloning of an Apobec-1-binding protein that also interacts with apolipoprotein B mRNA and evidence for its involvement in RNA editing.

Q8R4E9	CDT1_MOUSE	DNA replication factor Cdt1	12192004	Mouse geminin inhibits not only Cdt1-MCM6 interactions but also a novel intrinsic Cdt1 DNA binding activity.

P23415	GLRA1_HUMAN	Glycine receptor subunit alpha-1	2155780	Alpha subunit variants of the human glycine receptor: primary structures, functional expression and chromosomal localization of the corresponding genes.

Q6Q5K6	HUG1_YEAST	MEC1-mediated checkpoint protein HUG1	10490641	NORF5/HUG1 is a component of the MEC1-mediated checkpoint response to DNA damage and replication arrest in Saccharomyces cerevisiae.

O46201	A98AB_DROME	Accessory gland protein 98AB	9474779	New genes for male accessory gland proteins in Drosophila melanogaster.

Q283N4	URAD_MOUSE	2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase	16462750	Completing the uric acid degradation pathway through phylogenetic comparison of whole genomes.

Q9HDZ0	YK01_SCHPO	Uncharacterized protein P11E10.01	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P48563	MON2_YEAST	Protein MON2	12052896	Yeast Ysl2p, homologous to Sec7 domain guanine nucleotide exchange factors, functions in endocytosis and maintenance of vacuole integrity and interacts with the Arf-Like small GTPase Arl1p.

P36954	RPB9_HUMAN	DNA-directed RNA polymerase II subunit RPB9	9852112	Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.

O60895	RAMP2_HUMAN	Receptor activity-modifying protein 2	9620797	RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor.

Q12298	YD061_YEAST	Uncharacterized ABC transporter ATP-binding protein YDR061W	14562095	Global analysis of protein localization in budding yeast.

Q6LA54	YF48_SCHPO	Uncharacterized WD repeat-containing protein C3H5.08c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q15554	TERF2_HUMAN	Telomeric repeat-binding factor 2	10888888	Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres.

O54928	SOCS5_MOUSE	Suppressor of cytokine signaling 5	9419338	Twenty proteins containing a C-terminal SOCS box form five structural classes.

O74470	YQC8_SCHPO	Uncharacterized oxidoreductase C1739.08c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9QXJ1	APBB1_MOUSE	Amyloid beta A4 precursor protein-binding family B member 1	9407065	The WW domain of neural protein FE65 interacts with proline-rich motifs in Mena, the mammalian homolog of Drosophila enabled.

Q24509	STX5_DROME	Syntaxin-5	7929581	Localization of Sed5, a putative vesicle targeting molecule, to the cis-Golgi network involves both its transmembrane and cytoplasmic domains.

Q9FG67	MAM1_ARATH	Methylthioalkylmalate synthase 1, chloroplastic	11706188	A gene controlling variation in Arabidopsis glucosinolate composition is part of the methionine chain elongation pathway.

P26641	EF1G_HUMAN	Elongation factor 1-gamma	16548883	Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection.

P97613	PTTG1_RAT	Securin	9915854	Pituitary tumor-transforming gene protein associates with ribosomal protein S10 and a novel human homologue of DnaJ in testicular cells.

P83637	DS01_PHYOR	Dermaseptin-01	12379643	Dermaseptins from Phyllomedusa oreades and Phyllomedusa distincta. Anti-Trypanosoma cruzi activity without cytotoxicity to mammalian cells.

O35987	NSF1C_RAT	NSFL1 cofactor p47	12146947	Phospholipid species act as modulators in p97/p47-mediated fusion of Golgi membranes.

Q54QQ1	PHG2_DICDI	Serine/threonine-protein kinase phg2	16987957	A Phg2-Adrm1 pathway participates in the nutrient-controlled developmental response in Dictyostelium.

P26440	IVD_HUMAN	Isovaleryl-CoA dehydrogenase, mitochondrial	2063866	Molecular characterization of four different classes of mutations in the isovaleryl-CoA dehydrogenase gene responsible for isovaleric acidemia.

Q9NB04	PATJ_DROME	Patj homolog	11076972	Apical, lateral, and basal polarization cues contribute to the development of the follicular epithelium during Drosophila oogenesis.

Q04231	RAD33_YEAST	DNA repair protein RAD33	14562095	Global analysis of protein localization in budding yeast.

P40515	FIS1_YEAST	Mitochondria fission 1 protein	15809300	Novel structure of the N terminus in yeast Fis1 correlates with a specialized function in mitochondrial fission.

Q9UKQ9	KLK9_HUMAN	Kallikrein-9	11054574	Sequencing and expression analysis of the serine protease gene cluster located in chromosome 19q13 region.

P21695	GPDA_HUMAN	Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic	16460752	Crystal structures of human glycerol 3-phosphate dehydrogenase 1 (GPD1).

Q9Y5B9	SP16H_HUMAN	FACT complex subunit SPT16	10421373	The chromatin-specific transcription elongation factor FACT comprises human SPT16 and SSRP1 proteins.

P53277	SYF2_YEAST	Pre-mRNA-splicing factor SYF2	11842115	Functional and physical interactions between components of the Prp19p-associated complex.

Q4KML2	CRYD_DANRE	Cryptochrome DASH	15147276	Identification of cryptochrome DASH from vertebrates.

Q9VCY3	CSN6_DROME	COP9 signalosome complex subunit 6	12737805	The COP9 signalosome promotes degradation of Cyclin E during early Drosophila oogenesis.

O95947	TBX6_HUMAN	T-box transcription factor TBX6	9933572	The human TBX6 gene: cloning and assignment to chromosome 16p11.2.

Q54BD4	STATC_DICDI	Signal transducer and activator of transcription C	12506009	The Dictyostelium prestalk cell inducer DIF regulates nuclear accumulation of a STAT protein by controlling its rate of export from the nucleus.

P04982	RBSD_ECOLI	D-ribose pyranase	15060078	NMR application probes a novel and ubiquitous family of enzymes that alter monosaccharide configuration.

Q01663	AP1_SCHPO	AP-1-like transcription factor	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O15075	DCLK1_HUMAN	Serine/threonine-protein kinase DCLK1	16548883	Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection.

Q86WA6	BPHL_HUMAN	Valacyclovir hydrolase	7759552	Cloning and expression analysis of a novel human serine hydrolase with sequence similarity to prokaryotic enzymes involved in the degradation of aromatic compounds.

Q8JIR2	HR1A_TRIFL	Zinc metalloproteinase/disintegrin	12220724	Molecular cloning of HR1a and HR1b, high molecular hemorrhagic factors, from Trimeresurus flavoviridis venom.

P46800	GBLP_DICDI	Guanine nucleotide-binding protein subunit beta-like protein	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

Q8TF09	DLRB2_HUMAN	Dynein light chain roadblock-type 2	11750132	Identification of two novel human dynein light chain genes, DNLC2A and DNLC2B, and their expression changes in hepatocellular carcinoma tissues from 68 Chinese patients.

Q969T4	UB2E3_HUMAN	Ubiquitin-conjugating enzyme E2 E3	20061386	The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.

O75170	PP6R2_HUMAN	Serine/threonine-protein phosphatase 6 regulatory subunit 2	16769727	Protein phosphatase 6 subunit with conserved Sit4-associated protein domain targets IkappaBepsilon.

O14929	HAT1_HUMAN	Histone acetyltransferase type B catalytic subunit	9427644	Nucleosomal DNA regulates the core-histone-binding subunit of the human Hat1 acetyltransferase.

P39375	IRAD_ECOLI	Anti-adapter protein iraD	18383615	Multiple pathways for regulation of sigmaS (RpoS) stability in Escherichia coli via the action of multiple anti-adaptors.

P40961	PHB1_YEAST	Prohibitin-1	10835343	Prohibitins act as a membrane-bound chaperone for the stabilization of mitochondrial proteins.

Q9UMQ6	CAN11_HUMAN	Calpain-11	10409436	CAPN11: a calpain with high mRNA levels in testis and located on chromosome 6.

Q86Y13	DZIP3_HUMAN	E3 ubiquitin-protein ligase DZIP3	12538761	hRUL138, a novel human RNA-binding RING-H2 ubiquitin-protein ligase.

P08644	RASK_RAT	GTPase KRas	12594205	Suprachiasmatic nucleus circadian oscillatory protein, a novel binding partner of K-Ras in the membrane rafts, negatively regulates MAPK pathway.

Q9VTH4	SCLLA_DROME	Protein scylla	16423342	scylla and charybde, homologues of the human apoptotic gene RTP801, are required for head involution in Drosophila.

Q15853	USF2_HUMAN	Upstream stimulatory factor 2	8576131	Immunochemical characterization and transacting properties of upstream stimulatory factor isoforms.

Q55FF3	GSTA1_DICDI	Putative glutathione S-transferase alpha-1	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P0AEG4	DSBA_ECOLI	Thiol:disulfide interchange protein dsbA	1934062	Identification of a protein required for disulfide bond formation in vivo.

Q9WUL8	CITE4_MOUSE	Cbp/p300-interacting transactivator 4	12504852	Cloning of mouse Cited4, a member of the CITED family p300/CBP- binding transcriptional coactivators: induced expression in mammary epithelial cells.

Q9VBL7	MS57B_DROME	Accessory gland-specific peptide 57Db	7711745	Structure and regulation of a gene cluster for male accessory gland transcripts in Drosophila melanogaster.

P11498	PYC_HUMAN	Pyruvate carboxylase, mitochondrial	8048912	cDNA cloning of human kidney pyruvate carboxylase.

P35192	MAC1_YEAST	Metal-binding activator 1	8262047	MAC1, a nuclear regulatory protein related to Cu-dependent transcription factors is involved in Cu/Fe utilization and stress resistance in yeast.

Q8GW72	FUCO1_ARATH	Alpha-L-fucosidase 1	11788770	AtFXG1, an Arabidopsis gene encoding alpha-L-fucosidase active against fucosylated xyloglucan oligosaccharides.

P36002	PTK1_YEAST	Serine/threonine-protein kinase PTK1/STK1	7488221	Cloning of the gene encoding a putative serine/threonine protein kinase which enhances spermine uptake in Saccharomyces cerevisiae.

O94432	YHKF_SCHPO	Uncharacterized RNA-binding protein C660.15	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NZV1	CRIM1_HUMAN	Cysteine-rich motor neuron 1 protein	10642437	CRIM1, a novel gene encoding a cysteine-rich repeat protein, is developmentally regulated and implicated in vertebrate CNS development and organogenesis.

P11362	FGFR1_HUMAN	Basic fibroblast growth factor receptor 1	1652059	The human fibroblast growth factor receptor genes: a common structural arrangement underlies the mechanisms for generating receptor forms that differ in their third immunoglobulin domain.

Q9ZRF9	RPK1_ARATH	Probable LRR receptor-like serine/threonine-protein kinase RPK1	17543866	RPK1 and TOAD2 are two receptor-like kinases redundantly required for arabidopsis embryonic pattern formation.

Q9N0F3	SYSM_BOVIN	Seryl-tRNA synthetase, mitochondrial	10764807	Characterization and tRNA recognition of mammalian mitochondrial seryl-tRNA synthetase.

O88470	FOXL2_MOUSE	Forkhead box protein L2	15944199	Foxl2 is required for commitment to ovary differentiation.

Q90WV8	IBP5_XENLA	Insulin-like growth factor-binding protein 5	11709186	Neural and head induction by insulin-like growth factor signals.

Q03406	SLD5_YEAST	DNA replication complex GINS protein SLD5	12730134	GINS, a novel multiprotein complex required for chromosomal DNA replication in budding yeast.

Q9H4P4	RNF41_HUMAN	E3 ubiquitin-protein ligase NRDP1	14765125	Nrdp1-mediated degradation of the gigantic IAP, BRUCE, is a novel pathway for triggering apoptosis.

O00571	DDX3X_HUMAN	ATP-dependent RNA helicase DDX3X	10329544	Hepatitis C virus core protein interacts with a human DEAD box protein DDX3.

P18762	ADRB2_MOUSE	Beta-2 adrenergic receptor	2834198	Isoproterenol response following transfection of the mouse beta 2- adrenergic receptor gene into Y1 cells.

P46130	YBHC_ECOLI	Putative acyl-CoA thioester hydrolase ybhC	10806384	Proteomic analysis of the Escherichia coli outer membrane.

Q99MM4	TRAD1_RAT	TRAF-type zinc finger domain-containing protein 1	11748220	Cytokine-induced down-regulation of zfm1/splicing factor-1 promotes smooth muscle cell proliferation.

P24941	CDK2_HUMAN	Cell division protein kinase 2	15178429	NIRF induces G1 arrest and associates with Cdk2.

Q61624	ZN148_MOUSE	Zinc finger protein 148	9030551	Cloning and characterization of a transcription factor that binds to the proximal promoters of the two mouse type I collagen genes.

O33244	PSA_MYCTU	Proteasome subunit alpha	20461058	Structural basis for the assembly and gate closure mechanisms of the Mycobacterium tuberculosis 20S proteasome.

Q99676	ZN184_HUMAN	Zinc finger protein 184	9073517	Identification of a novel Krueppel-related zinc finger gene (ZNF184) mapping to 6p21.3.

P29506	UNC4_CAEEL	Homeobox protein unc-4	1347150	C. elegans unc-4 gene encodes a homeodomain protein that determines the pattern of synaptic input to specific motor neurons.

Q8IUQ4	SIAH1_HUMAN	E3 ubiquitin-protein ligase SIAH1	11389840	Siah-1 mediates a novel beta-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein.

P93022	ARFG_ARATH	Auxin response factor 7	14729917	MASSUGU2 encodes Aux/IAA19, an auxin-regulated protein that functions together with the transcriptional activator NPH4/ARF7 to regulate differential growth responses of hypocotyl and formation of lateral roots in Arabidopsis thaliana.

Q05164	HPF1_YEAST	Haze protective factor 1	11935221	Sequence-based approach for identification of cell wall proteins in Saccharomyces cerevisiae.

O54998	FKBP7_MOUSE	Peptidyl-prolyl cis-trans isomerase FKBP7	9806833	Molecular cloning, characterization, and chromosomal localization of FKBP23, a novel FK506-binding protein with Ca2+-binding ability.

P23686	METK1_ARATH	S-adenosylmethionine synthase 1	2535470	Strong cellular preference in the expression of a housekeeping gene of Arabidopsis thaliana encoding S-adenosylmethionine synthetase.

Q9BYM8	UB7I3_HUMAN	RanBP-type and C3HC4-type zinc finger-containing protein 1	17449468	RBCK1 negatively regulates tumor necrosis factor- and interleukin-1- triggered NF-kappaB activation by targeting TAB2/3 for degradation.

Q9VKU7	GCP4_DROME	Gamma-tubulin complex component 4 homolog	10562286	Human 76p: a new protein member of the gamma-tubulin associated protein family.

Q91ZR5	CTSR1_MOUSE	Cation channel sperm-associated protein 1	11595941	A sperm ion channel required for sperm motility and male fertility.

Q9UKV8	AGO2_HUMAN	Protein argonaute-2	15973356	TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing.

P53911	EAF7_YEAST	Chromatin modification-related protein EAF7	14562095	Global analysis of protein localization in budding yeast.

Q96288	STO_ARATH	Salt tolerance protein	8662738	Two classes of plant cDNA clones differentially complement yeast calcineurin mutants and increase salt tolerance of wild-type yeast.

Q03248	BUP1_RAT	Beta-ureidopropionase	8449931	Cloning, sequencing, and expression of a cDNA encoding beta-alanine synthase from rat liver.

Q06168	SFH1_YEAST	Chromatin structure-remodeling complex subunit SFH1	12183366	Chromatin remodeling by RSC involves ATP-dependent DNA translocation.

O14763	TR10B_HUMAN	Tumor necrosis factor receptor superfamily member 10B	10549288	Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5.

Q06639	RSC3_YEAST	Chromatin structure-remodeling complex protein RSC3	11336698	A Rsc3/Rsc30 zinc cluster dimer reveals novel roles for the chromatin remodeler RSC in gene expression and cell cycle control.

Q8N0W4	NLGNX_HUMAN	Neuroligin-4, X-linked	11368788	Identification of a novel neuroligin in humans which binds to PSD-95 and has a widespread expression.

Q570C0	TIR1_ARATH	Protein TRANSPORT INHIBITOR RESPONSE 1	18391211	Small-molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling.

Q10222	PTA1_SCHPO	mRNA cleavage and polyadenylation specificity factor complex subunit pta1	14617822	A comparative analysis of an orthologous proteomic environment in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe.

Q9JJ09	NPT2B_RAT	Sodium-dependent phosphate transport protein 2B	12893629	Regulation of intestinal NaPi-IIb cotransporter gene expression by estrogen.

Q9BSI4	TINF2_HUMAN	TERF1-interacting nuclear factor 2	10581025	TIN2, a new regulator of telomere length in human cells.

P83174	HCY1_CANPG	Hemocyanin subunit 1	2620501	The relationship between N-terminal sequences and immunological characterization of crustacean hemocyanins.

O13928	RHO3_SCHPO	GTP-binding protein rho3	12415007	The small GTPase Rho3 and the diaphanous/formin For3 function in polarized cell growth in fission yeast.

P67662	AAER_ECOLI	HTH-type transcriptional activator AaeR	15489430	Characterization of the Escherichia coli AaeAB efflux pump: a metabolic relief valve?

Q86UP0	CAD24_HUMAN	Cadherin-24	12734196	Characterization of cadherin-24, a novel alternatively spliced type II cadherin.

O45583	GMD2_CAEEL	GDP-mannose 4,6 dehydratase 2	16650000	Reconstitution in vitro of the GDP-fucose biosynthetic pathways of Caenorhabditis elegans and Drosophila melanogaster.

Q5S2C4	NCKP1_ARATH	Protein NAP1	15296760	Arabidopsis GNARLED encodes a NAP125 homolog that positively regulates ARP2/3.

Q9Y4K3	TRAF6_HUMAN	TNF receptor-associated factor 6	10383454	IRAK-M is a novel member of the Pelle/interleukin-1 receptor- associated kinase (IRAK) family.

P48146	NPBW2_HUMAN	Neuropeptides B/W receptor type 2	7590751	The cloning and chromosomal mapping of two novel human opioid- somatostatin-like receptor genes, GPR7 and GPR8, expressed in discrete areas of the brain.

O14492	SH2B2_HUMAN	SH2B adapter protein 2	9989826	APS, an adaptor protein containing PH and SH2 domains, is associated with the PDGF receptor and c-Cbl and inhibits PDGF-induced mitogenesis.

P52890	ATF1_SCHPO	Transcription factor atf1	9391101	Transcription factor Mts1/Mts2 (Atf1/Pcr1, Gad7/Pcr1) activates the M26 meiotic recombination hotspot in Schizosaccharomyces pombe.

Q9UT85	YIPC_SCHPO	Uncharacterized WD repeat-containing protein C343.04c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P10960	SAP_RAT	Sulfated glycoprotein 1	8573994	Molecular role of sulfated glycoprotein-1 (SGP-1/prosaposin) in Sertoli cells.

P17119	KAR3_YEAST	Kinesin-like protein KAR3	11729143	The Kar3-interacting protein Cik1p plays a critical role in passage through meiosis I in Saccharomyces cerevisiae.

Q12114	CHS5_YEAST	Chitin biosynthesis protein CHS5	9111317	CHS5, a gene involved in chitin synthesis and mating in Saccharomyces cerevisiae.

P69834	ISPD_ARATH	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic	10841550	Biosynthesis of terpenoids: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase of Arabidopsis thaliana.

Q9R0A3	SPAT7_RAT	Spermatogenesis-associated protein 7 homolog	12736779	A novel gene, RSD-3/HSD-3.1, encodes a meiotic-related protein expressed in rat and human testis.

P02752	RBP_CHICK	Riboflavin-binding protein	3997791	Comparison of the amino acid sequences of hen plasma-, yolk-, and white-riboflavin binding proteins.

Q96ST3	SIN3A_HUMAN	Paired amphipathic helix protein Sin3a	11259580	PSF is a novel corepressor that mediates its effect through Sin3A and the DNA binding domain of nuclear hormone receptors.

Q9FVC8	DAPA2_ARATH	Dihydrodipicolinate synthase 2, chloroplastic	11069709	Identification of an Arabidopsis thaliana mutant accumulating threonine resulting from mutation in a new dihydrodipicolinate synthase gene.

P87141	MIP1_SCHPO	WD repeat-containing protein mip1	10648609	Novel WD-repeat protein Mip1p facilitates function of the meiotic regulator Mei2p in fission yeast.

P25365	SED4_YEAST	Putative guanine nucleotide-exchange factor SED4	7593162	SED4 encodes a yeast endoplasmic reticulum protein that binds Sec16p and participates in vesicle formation.

P89114	SAE3_YEAST	Pachytene arrest protein SAE3	15620352	A protein complex containing Mei5 and Sae3 promotes the assembly of the meiosis-specific RecA homolog Dmc1.

P10634	CP2DQ_RAT	Cytochrome P450 2D26	9434752	Expression of four rat CYP2D isoforms in Saccharomyces cerevisiae and their catalytic specificity.

P30630	LIN9_CAEEL	Protein lin-9	10974557	The C. elegans gene lin-9, which acts in an Rb-related pathway, is required for gonadal sheath cell development and encodes a novel protein.

Q9VK33	SMBT_DROME	Polycomb protein Sfmbt	16618800	A Polycomb group protein complex with sequence-specific DNA-binding and selective methyl-lysine-binding activities.

Q05827	HOR7_YEAST	Protein HOR7	9234669	Characterization of two new genes down-regulated by alpha-factor.

P07207	NOTCH_DROME	Neurogenic locus Notch protein	15620650	Regulation of notch endosomal sorting and signaling by Drosophila Nedd4 family proteins.

O75783	RHBL1_HUMAN	Rhomboid-related protein 1	9662444	Characterization of a mammalian cDNA encoding a protein with high sequence similarity to the Drosophila regulatory protein Rhomboid.

Q9WTZ9	BEX3_MOUSE	Protein BEX3	10764727	NADE, a p75NTR-associated cell death executor, is involved in signal transduction mediated by the common neurotrophin receptor p75NTR.

Q96N16	JKIP1_HUMAN	Janus kinase and microtubule-interacting protein 1	14718537	Marlin-1, a novel RNA-binding protein associates with GABA receptors.

Q9GSX9	RIC8_CAEEL	Synembryn	10985349	RIC-8 (Synembryn): a novel conserved protein that is required for Gq alpha signaling in the C. elegans nervous system.

O74848	MU146_SCHPO	Meiotically up-regulated gene 146 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P05093	CP17A_HUMAN	Steroid 17-alpha-hydroxylase/17,20 lyase	2808364	Deletion of a phenylalanine in the N-terminal region of human cytochrome P-450(17 alpha) results in partial combined 17 alpha- hydroxylase/17,20-lyase deficiency.

P23415	GLRA1_HUMAN	Glycine receptor subunit alpha-1	8298642	Mutations in the alpha 1 subunit of the inhibitory glycine receptor cause the dominant neurologic disorder, hyperekplexia.

Q7XJR2	ANTR3_ARATH	Probable anion transporter 3, chloroplastic	18086223	Functional analysis of the Arabidopsis PHT4 family of intracellular phosphate transporters.

P0AFK4	POTB_ECOLI	Spermidine/putrescine transport system permease protein potB	1939142	Characteristics of the gene for a spermidine and putrescine transport system that maps at 15 min on the Escherichia coli chromosome.

O14229	SFC1_SCHPO	Transcription factor tau subunit sfc1	10906331	Isolation and cloning of four subunits of a fission yeast TFIIIC complex that includes an ortholog of the human regulatory protein TFIIICbeta.

Q9JJN6	CNBP1_MOUSE	Beta-catenin-interacting protein 1	10898789	Inhibition of Wnt signaling by ICAT, a novel beta-catenin-interacting protein.

Q9HGK2	HOP2_SCHPO	Homologous-pairing protein 2	11447128	A novel meiosis-specific protein of fission yeast, Meu13p, promotes homologous pairing independently of homologous recombination.

P38348	HSM3_YEAST	DNA mismatch repair protein HSM3	14562095	Global analysis of protein localization in budding yeast.

Q14566	MCM6_HUMAN	DNA replication licensing factor MCM6	11095689	The human homolog of Saccharomyces cerevisiae Mcm10 interacts with replication factors and dissociates from nuclease-resistant nuclear structures in G(2) phase.

P19171	CHIB_ARATH	Basic endochitinase B	7610160	Analysis of ethylene signal-transduction kinetics associated with seedling-growth response and chitinase induction in wild-type and mutant Arabidopsis.

Q9QXS4	CMLO3_RAT	Probable N-acetyltransferase CML3	11397015	Overexpression of camello, a member of a novel protein family, reduces blastomere adhesion and inhibits gastrulation in Xenopus laevis.

Q9Y0T2	FBXA_DICDI	F-box/WD repeat-containing protein A	10725352	Dictyostelium amoebae lacking an F-box protein form spores rather than stalk in chimeras with wild type.

P42126	D3D2_HUMAN	3,2-trans-enoyl-CoA isomerase, mitochondrial	7818490	Delta 3, delta 2-enoyl-CoA isomerase is the protein that copurifies with human glutathione S-transferases from S-hexylglutathione affinity matrices.

Q12982	BNIP2_HUMAN	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2	7954800	Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins.

Q9SD67	FTSH7_ARATH	ATP-dependent zinc metalloprotease FTSH 7, chloroplastic	14630971	Coordinated regulation and complex formation of yellow variegated1 and yellow variegated2, chloroplastic FtsH metalloproteases involved in the repair cycle of photosystem II in Arabidopsis thylakoid membranes.

Q9Y291	RT33_HUMAN	28S ribosomal protein S33, mitochondrial	11279123	The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present.

P32792	YHH7_YEAST	UPF0744 protein YSC83	16407407	Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins.

P28026	WNT8_XENLA	Protein Wnt-8	10067895	The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals.

Q01802	AATM_YEAST	Aspartate aminotransferase, mitochondrial	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Q99278	MED11_YEAST	Mediator of RNA polymerase II transcription subunit 11	9812975	Identification of new mediator subunits in the RNA polymerase II holoenzyme from Saccharomyces cerevisiae.

Q5VST9	OBSCN_HUMAN	Obscurin	11448995	Obscurin, a giant sarcomeric Rho guanine nucleotide exchange factor protein involved in sarcomere assembly.

Q9H310	RHBG_HUMAN	Ammonium transporter Rh type B	11024028	Rh type B glycoprotein is a new member of the Rh superfamily and a putative ammonia transporter in mammals.

P02794	FRIH_HUMAN	Ferritin heavy chain	3020541	Cloning, characterization, expression, and chromosomal localization of a human ferritin heavy-chain gene.

P06028	GLPB_HUMAN	Glycophorin-B	2734312	Structural organization of glycophorin A and B genes: glycophorin B gene evolved by homologous recombination at Alu repeat sequences.

P17433	SPI1_MOUSE	Transcription factor PU.1	8626664	The transcription factor Spi-1/PU.1 binds RNA and interferes with the RNA-binding protein p54nrb.

P32445	RIM1_YEAST	Single-stranded DNA-binding protein RIM1, mitochondrial	1324172	A single-stranded DNA binding protein required for mitochondrial DNA replication in S. cerevisiae is homologous to E. coli SSB.

O14042	FMP32_SCHPO	Protein fmp32, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q86WA8	LONP2_HUMAN	Lon protease homolog 2, peroxisomal	14561759	Proteomic analysis of rat liver peroxisome: presence of peroxisome- specific isozyme of Lon protease.

P08709	FA7_HUMAN	Coagulation factor VII	8598903	The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor.

Q99MZ8	LASP1_RAT	LIM and SH3 domain protein 1	10806114	The LIM and SH3 domain-containing protein, lasp-1, may link the cAMP signaling pathway with dynamic membrane restructuring activities in ion transporting epithelia.

P12544	GRAA_HUMAN	Granzyme A	12819770	Crystal structure of the apoptosis-inducing human granzyme A dimer.

P16455	MGMT_HUMAN	Methylated-DNA--protein-cysteine methyltransferase	2188979	cDNA cloning and chromosomal assignment of the human O6- methylguanine-DNA methyltransferase. cDNA expression in Escherichia coli and gene expression in human cells.

Q75IP6	KU80_ORYSJ	ATP-dependent DNA helicase 2 subunit KU80	19923234	OsKu70 is associated with developmental growth and genome stability in rice.

O13710	SMC5_SCHPO	Structural maintenance of chromosomes protein 5	16478984	The Nse5-Nse6 dimer mediates DNA repair roles of the Smc5-Smc6 complex.

Q9VB08	RING1_DROME	E3 ubiquitin-protein ligase RING1	12963114	Molecular and genetic analysis of the Polycomb group gene Sex combs extra/Ring in Drosophila.

O14063	IMA1_SCHPO	Importin subunit alpha-1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q04178	HPRT_YEAST	Hypoxanthine-guanine phosphoribosyltransferase	14562095	Global analysis of protein localization in budding yeast.

P25582	SPB1_YEAST	AdoMet-dependent rRNA methyltransferase SPB1	10556316	Spb1p is a putative methyltransferase required for 60S ribosomal subunit biogenesis in Saccharomyces cerevisiae.

Q9ZVH3	ORC6_ARATH	Origin recognition complex subunit 6	16179646	The genes encoding Arabidopsis ORC subunits are E2F targets and the two ORC1 genes are differently expressed in proliferating and endoreplicating cells.

Q9ZR72	AB1B_ARATH	ABC transporter B family member 1	14517332	TWISTED DWARF1, a unique plasma membrane-anchored immunophilin-like protein, interacts with Arabidopsis multidrug resistance-like transporters AtPGP1 and AtPGP19.

Q13127	REST_HUMAN	RE1-silencing transcription factor	7697725	REST: a mammalian silencer protein that restricts sodium channel gene expression to neurons.

Q14654	IRK11_HUMAN	ATP-sensitive inward rectifier potassium channel 11	8923010	Mutation of the pancreatic islet inward rectifier Kir6.2 also leads to familial persistent hyperinsulinemic hypoglycemia of infancy.

Q9ES52	SHIP1_MOUSE	Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1	8654924	p150Ship, a signal transduction molecule with inositol polyphosphate- 5-phosphatase activity.

O95251	MYST2_HUMAN	Histone acetyltransferase MYST2	16387653	ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.

Q99880	H2B1L_HUMAN	Histone H2B type 1-L	9439656	The human histone gene cluster at the D6S105 locus.

Q96MT3	PRIC1_HUMAN	Prickle-like protein 1	14645515	REST/NRSF-interacting LIM domain protein, a putative nuclear translocation receptor.

P64943	PAFA_MYCTU	Pup--protein ligase	18832610	Ubiquitin-like protein involved in the proteasome pathway of Mycobacterium tuberculosis.

P87229	YC03_SCHPO	Uncharacterized protein C4G3.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q6EVK6	BRM_ARATH	ATP-dependent helicase BRM	17293567	Unique, shared, and redundant roles for the Arabidopsis SWI/SNF chromatin remodeling ATPases BRAHMA and SPLAYED.

P22223	CADH3_HUMAN	Cadherin-3	2793940	Molecular cloning of a human Ca2+-dependent cell-cell adhesion molecule homologous to mouse placental cadherin: its low expression in human placental tissues.

P15531	NDKA_HUMAN	Nucleoside diphosphate kinase A	1851158	Nucleoside diphosphate kinase from human erythrocytes. Structural characterization of the two polypeptide chains responsible for heterogeneity of the hexameric enzyme.

O75317	UBP12_HUMAN	Ubiquitin carboxyl-terminal hydrolase 12	9615226	An evolutionarily conserved gene on human chromosome 5q33-q34, UBH1, encodes a novel deubiquitinating enzyme.

O59826	KCAB_SCHPO	Putative voltage-gated potassium channel subunit beta	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q15021	CND1_HUMAN	Condensin complex subunit 1	11136719	Chromosome condensation by a human condensin complex in Xenopus egg extracts.

P30657	PSB4_YEAST	Proteasome component PRE4	9087403	Structure of 20S proteasome from yeast at 2.4-A resolution.

O95989	NUDT3_HUMAN	Diphosphoinositol polyphosphate phosphohydrolase 1	10585413	Site-directed mutagenesis of diphosphoinositol polyphosphate phosphohydrolase, a dual specificity NUDT enzyme that attacks diadenosine polyphosphates and diphosphoinositol polyphosphates.

Q8K382	DEN1A_MOUSE	DENN domain-containing protein 1A	17182770	Connecdenn, a novel DENN domain-containing protein of neuronal clathrin-coated vesicles functioning in synaptic vesicle endocytosis.

Q00653	NFKB2_HUMAN	Nuclear factor NF-kappa-B p100 subunit	1760839	B cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-kappa B p50.

P11747	TAF13_YEAST	Transcription initiation factor TFIID subunit 13	10788514	Identification of two novel TAF subunits of the yeast Saccharomyces cerevisiae TFIID complex.

Q9H2C8	O51V1_HUMAN	Olfactory receptor 51V1	11121057	Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.

O15020	SPTN2_HUMAN	Spectrin beta chain, brain 2	9826670	A widely expressed betaIII spectrin associated with Golgi and cytoplasmic vesicles.

Q94CL9	KRP7_ARATH	Cyclin-dependent kinase inhibitor 7	18948957	Control of plant germline proliferation by SCF(FBL17) degradation of cell cycle inhibitors.

P39952	OXA1_YEAST	Mitochondrial inner membrane protein OXA1	9482871	Oxa1p, an essential component of the N-tail protein export machinery in mitochondria.

Q9ES57	MO2R1_MOUSE	Cell surface glycoprotein CD200 receptor 1	15274657	Structural and functional heterogeneity in the CD200R family of immunoregulatory molecules and their expression at the feto-maternal interface.

Q5YKK9	OPN4_FELCA	Melanopsin	15842746	Melanopsin (Opn4) positive cells in the cat retina are randomly distributed across the ganglion cell layer.

P03886	NU1M_HUMAN	NADH-ubiquinone oxidoreductase chain 1	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

P92958	KIN11_ARATH	SNF1-related protein kinase catalytic subunit alpha KIN11	11387208	SKP1-SnRK protein kinase interactions mediate proteasomal binding of a plant SCF ubiquitin ligase.

Q92560	BAP1_HUMAN	Ubiquitin carboxyl-terminal hydrolase BAP1	20436459	Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB.

Q8N4C6	NIN_HUMAN	Ninein	15147888	A novel ninein-interaction protein, CGI-99, blocks ninein phosphorylation by GSK3beta and is highly expressed in brain tumors.

P13942	COBA2_HUMAN	Collagen alpha-2(XI) chain	8838804	The human alpha 2(XI) collagen gene (COL11A2): completion of coding information, identification of the promoter sequence, and precise localization within the major histocompatibility complex reveal overlap with the KE5 gene.

P49864	GRAK_RAT	Granzyme K	8133042	Purification and cloning of a novel serine protease, RNK-Tryp-2, from the granules of a rat NK cell leukemia.

O74510	YJD7_SCHPO	Uncharacterized membrane protein C594.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O94481	TFC5_SCHPO	Transcription factor TFIIIB component B''	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q91WW7	PLPL3_MOUSE	Patatin-like phospholipase domain-containing protein 3	11431482	Adiponutrin, a transmembrane protein corresponding to a novel dietary- and obesity-linked mRNA specifically expressed in the adipose lineage.

Q9NTJ3	SMC4_HUMAN	Structural maintenance of chromosomes protein 4	9789013	Identification of two distinct human SMC protein complexes involved in mitotic chromosome dynamics.

Q99104	MYO5A_MOUSE	Myosin-Va	11887186	Identification of an organelle receptor for myosin-Va.

O75362	ZN217_HUMAN	Zinc finger protein 217	9671742	Positional cloning of ZNF217 and NABC1: genes amplified at 20q13.2 and overexpressed in breast carcinoma.

P32746	PYRD_ARATH	Dihydroorotate dehydrogenase, mitochondrial	1303803	Complementation of Saccharomyces cerevisiae auxotrophic mutants by Arabidopsis thaliana cDNAs.

Q8VC28	AK1CD_MOUSE	Aldo-keto reductase family 1 member C13	10526179	Cloning and characterization of two novel aldo-keto reductases (AKR1C12 and AKR1C13) from mouse stomach.

O54824	IL16_MOUSE	Pro-interleukin-16	9637508	Conservation of structure and function between human and murine IL- 16.

Q91X52	DCXR_MOUSE	L-xylulose reductase	11882650	Molecular characterization of mammalian dicarbonyl/L-xylulose reductase and its localization in kidney.

Q96AP0	ACD_HUMAN	Adrenocortical dysplasia protein homolog	15181449	PTOP interacts with POT1 and regulates its localization to telomeres.

P07882	CEL_RAT	Bile salt-activated lipase	1999399	Site-specific mutagenesis of an essential histidine residue in pancreatic cholesterol esterase.

Q9V6Q2	CID_DROME	Histone H3-like centromeric protein cid	11483958	The role of Drosophila CID in kinetochore formation, cell-cycle progression and heterochromatin interactions.

Q12692	H2AZ_YEAST	Histone H2A.Z	14690608	A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1.

Q9Z311	MECR_RAT	Trans-2-enoyl-CoA reductase, mitochondrial	9795230	Nuclear receptor binding factor-1 (NRBF-1), a protein interacting with a wide spectrum of nuclear hormone receptors.

P04637	P53_HUMAN	Cellular tumor antigen p53	11546806	Cloning and characterization of a p53-related protein kinase expressed in interleukin-2-activated cytotoxic T-cells, epithelial tumor cell lines, and the testes.

Q9Y0H4	SUDX_DROME	E3 ubiquitin-protein ligase Su(dx)	15620650	Regulation of notch endosomal sorting and signaling by Drosophila Nedd4 family proteins.

P39305	ULAE_ECOLI	L-ribulose-5-phosphate 3-epimerase ulaE	11741871	Utilization of L-ascorbate by Escherichia coli K-12: assignments of functions to products of the yjf-sga and yia-sgb operons.

O43676	NDUB3_HUMAN	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

O74304	WIN1_SCHPO	MAP kinase kinase kinase win1	9693384	The fission yeast mitotic regulator win1+ encodes an MAP kinase kinase kinase that phosphorylates and activates Wis1 MAP kinase kinase in response to high osmolarity.

Q9H2K2	TNKS2_HUMAN	Tankyrase-2	11278563	Identification of a novel human tankyrase through its interaction with the adaptor protein Grb14.

Q8R5M5	ACMSD_RAT	2-amino-3-carboxymuconate-6-semialdehyde decarboxylase	11802786	Purification and molecular cloning of rat 2-amino-3-carboxymuconate- 6-semialdehyde decarboxylase.

Q9NDM2	GUTR1_DROME	Gustatory receptor trehalose 1	11566105	Trehalose sensitivity in Drosophila correlates with mutations in and expression of the gustatory receptor gene Gr5a.

O59674	YB8B_SCHPO	Uncharacterized mitochondrial carrier C29A3.11c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q55F94	DLPA_DICDI	Dynamin-like protein A	18809930	Evolutionary linkage between eukaryotic cytokinesis and chloroplast division by dynamin proteins.

P53877	IPI3_YEAST	Pre-rRNA-processing protein IPI3	14759368	High-definition macromolecular composition of yeast RNA-processing complexes.

P27697	ABC1_YEAST	Protein ABC1, mitochondrial	1648478	ABC1, a novel yeast nuclear gene has a dual function in mitochondria: it suppresses a cytochrome b mRNA translation defect and is essential for the electron transfer in the bc 1 complex.

Q05329	DCE2_HUMAN	Glutamate decarboxylase 2	1549570	Two human glutamate decarboxylases, 65-kDa GAD and 67-kDa GAD, are each encoded by a single gene.

O15205	UBD_HUMAN	Ubiquitin D	17889673	E1-L2 activates both ubiquitin and FAT10.

Q7Z2E3	APTX_HUMAN	Aprataxin	14755728	Aprataxin, the causative protein for EAOH is a nuclear protein with a potential role as a DNA repair protein.

Q08117	AES_HUMAN	Amino-terminal enhancer of split	9809752	Genomic organization and chromosome localization to band 19p13.3 of the human AES gene: gene product exhibits strong similarity to the N- terminal domain of Drosophila enhancer of split Groucho protein.

Q93WC4	IAA29_ARATH	Auxin-responsive protein IAA29	12036262	Genetics of Aux/IAA and ARF action in plant growth and development.

Q62780	DDX46_RAT	Probable ATP-dependent RNA helicase DDX46	7797571	A putative mammalian RNA helicase with an arginine-serine-rich domain colocalizes with a splicing factor.

P11654	PO210_RAT	Nuclear pore membrane glycoprotein 210	11453980	Biochemical characterization of nuclear pore complex protein gp210 oligomers.

Q9NS73	MBIP1_HUMAN	MAP3K12-binding inhibitory protein 1	10801814	MAPK upstream kinase (MUK)-binding inhibitory protein, a negative regulator of MUK/Dual leucine zipper-bearing kinase/leucine zipper protein kinase.

Q14137	BOP1_HUMAN	Ribosome biogenesis protein BOP1	17353269	Interdependence of Pes1, Bop1, and WDR12 controls nucleolar localization and assembly of the PeBoW complex required for maturation of the 60S ribosomal subunit.

Q55FG3	VP13C_DICDI	Putative vacuolar protein sorting-associated protein 13C	10402673	tip genes act in parallel pathways of early Dictyostelium development.

P34896	GLYC_HUMAN	Serine hydroxymethyltransferase, cytosolic	9753690	The crystal structure of human cytosolic serine hydroxymethyltransferase: a target for cancer chemotherapy.

Q92358	BQT1_SCHPO	Telomere bouquet protein 1	16615890	Meiotic proteins bqt1 and bqt2 tether telomeres to form the bouquet arrangement of chromosomes.

P34709	TRA2_CAEEL	Sex-determining transformer protein 2	11124807	Direct protein-protein interaction between the intracellular domain of TRA-2 and the transcription factor TRA-1A modulates feminizing activity in C. elegans.

Q12151	UPC2_YEAST	Sterol uptake control protein 2	11533229	Upc2p and Ecm22p, dual regulators of sterol biosynthesis in Saccharomyces cerevisiae.

O16000	STX1A_CAEEL	Syntaxin-1A homolog	10377425	Neurosecretory control of aging in Caenorhabditis elegans.

O88764	DAPK3_RAT	Death-associated protein kinase 3	10602480	Interaction partners of Dlk/ZIP kinase: co-expression of Dlk/ZIP kinase and Par-4 results in cytoplasmic retention and apoptosis.

P54852	EMP3_HUMAN	Epithelial membrane protein 3	8996089	Characterization of a tumor-associated gene, a member of a novel family of genes encoding membrane glycoproteins.

P08985	H2AV_DROME	Histone H2A.v	15528408	Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions.

Q8BJL0	SMAL1_MOUSE	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1	10857751	Cloning and characterization of HARP/SMARCAL1: a prokaryotic HepA- related SNF2 helicase protein from human and mouse.

Q64279	HAND1_MOUSE	Heart- and neural crest derivatives-expressed protein 1	10924525	The basic helix-loop-helix transcription factors dHAND and eHAND exhibit dimerization characteristics that suggest complex regulation of function.

P20449	DBP5_YEAST	ATP-dependent RNA helicase DBP5	9564047	Dbp5p, a cytosolic RNA helicase, is required for poly(A)+ RNA export.

Q9SJN0	ABI5_ARATH	Protein ABSCISIC ACID-INSENSITIVE 5	16463099	Transcriptional regulation of ABI3- and ABA-responsive genes including RD29B and RD29A in seeds, germinating embryos, and seedlings of Arabidopsis.

Q9QXT5	EGFL7_MOUSE	Epidermal growth factor-like protein 7	15085134	The endothelial-cell-derived secreted factor Egfl7 regulates vascular tube formation.

Q12418	GIS3_YEAST	Protein GIS3	10628841	Yeast genes GIS1-4: multicopy suppressors of the Gal- phenotype of snf1 mig1 srb8/10/11 cells.

Q9Z2C8	YBOX2_MOUSE	Y-box-binding protein 2	15665108	The DNA/RNA-binding protein MSY2 marks specific transcripts for cytoplasmic storage in mouse male germ cells.

O60494	CUBN_HUMAN	Cubilin	10080186	Mutations in CUBN, encoding the intrinsic factor-vitamin B12 receptor, cubilin, cause hereditary megaloblastic anaemia 1.

P09208	INSR_DROME	Insulin-like receptor	3014506	Isolation of a Drosophila genomic sequence homologous to the kinase domain of the human insulin receptor and detection of the phosphorylated Drosophila receptor with an anti-peptide antibody.

Q12171	MDM32_YEAST	Mitochondrial distribution and morphology protein 32	15631992	Mdm31 and Mdm32 are inner membrane proteins required for maintenance of mitochondrial shape and stability of mitochondrial DNA nucleoids in yeast.

P48506	GSH1_HUMAN	Glutamate--cysteine ligase catalytic subunit	12663448	A novel missense mutation in the gamma-glutamylcysteine synthetase catalytic subunit gene causes both decreased enzymatic activity and glutathione production.

P35232	PHB_HUMAN	Prohibitin	11302691	Mammalian prohibitin proteins respond to mitochondrial stress and decrease during cellular senescence.

P32945	PPQ1_YEAST	Serine/threonine-protein phosphatase PPQ	8269960	PPQ, a novel protein phosphatase containing a Ser + Asn-rich amino- terminal domain, is involved in the regulation of protein synthesis.

O43889	CREB3_HUMAN	Cyclic AMP-responsive element-binding protein 3	10675342	Hepatitis C virus core protein-induced loss of LZIP function correlates with cellular transformation.

Q03020	ISU1_YEAST	Iron sulfur cluster assembly protein 1, mitochondrial	12756240	Ssq1, a mitochondrial Hsp70 involved in iron-sulfur (Fe/S) center biogenesis. Similarities to and differences from its bacterial counterpart.

Q9V3K3	RUVB2_DROME	RuvB-like helicase 2	16087886	Myc interacts genetically with Tip48/Reptin and Tip49/Pontin to control growth and proliferation during Drosophila development.

Q9UTM9	FAP2_SCHPO	L-saccharopine oxidase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P20933	ASPG_HUMAN	N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	1281977	Purification and structure of human liver aspartylglucosaminidase.

Q01066	PDE1B_RAT	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	1326532	A polymerase chain reaction strategy to identify and clone cyclic nucleotide phosphodiesterase cDNAs. Molecular cloning of the cDNA encoding the 63-kDa calmodulin-dependent phosphodiesterase.

Q9T2L0	CB2B_SPIOL	Chlorophyll a-b binding protein	1894641	Tandem mass spectrometry identifies sites of three post-translational modifications of spinach light-harvesting chlorophyll protein II. Proteolytic cleavage, acetylation, and phosphorylation.

Q8BJ56	PLPL2_MOUSE	Patatin-like phospholipase domain-containing protein 2	16679289	Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome.

P0ABZ6	SURA_ECOLI	Chaperone surA	15840585	The periplasmic chaperone SurA exploits two features characteristic of integral outer membrane proteins for selective substrate recognition.

P39732	GIP4_YEAST	GLC7-interacting protein 4	14562095	Global analysis of protein localization in budding yeast.

Q9VH07	RUVB1_DROME	RuvB-like helicase 1	16618800	A Polycomb group protein complex with sequence-specific DNA-binding and selective methyl-lysine-binding activities.

Q9UKE5	TNIK_HUMAN	TRAF2 and NCK-interacting protein kinase	15342639	The Traf2- and Nck-interacting kinase as a putative effector of Rap2 to regulate actin cytoskeleton.

P34758	SCD5_YEAST	Protein SCD5	8688556	SCD5, a suppressor of clathrin deficiency, encodes a novel protein with a late secretory function in yeast.

Q04031	RRP17_YEAST	Ribosomal RNA-processing protein 17	10684247	The yeast nuclear pore complex: composition, architecture, and transport mechanism.

Q13825	AUHM_HUMAN	Methylglutaconyl-CoA hydratase, mitochondrial	7892223	AUH, a gene encoding an AU-specific RNA binding protein with intrinsic enoyl-CoA hydratase activity.

Q923Y7	TAAR4_RAT	Trace amine-associated receptor 4	11459929	Trace amines: identification of a family of mammalian G protein- coupled receptors.

P16066	ANPRA_HUMAN	Atrial natriuretic peptide receptor 1	1672777	Selective activation of the B natriuretic peptide receptor by C-type natriuretic peptide (CNP).

Q96524	CRY2_ARATH	Cryptochrome-2	17259260	CRYPTOCHROME2 in vascular bundles regulates flowering in Arabidopsis.

P23589	CAH5A_MOUSE	Carbonic anhydrase 5A, mitochondrial	7937950	Mitochondrial carbonic anhydrase (isozyme V) in mouse and rat: cDNA cloning, expression, subcellular localization, processing, and tissue distribution.

Q07984	SSRD_RAT	Translocon-associated protein subunit delta	7916687	A tetrameric complex of membrane proteins in the endoplasmic reticulum.

P07902	GALT_HUMAN	Galactose-1-phosphate uridylyltransferase	1427861	The human galactose-1-phosphate uridyltransferase gene.

P52491	UBC12_YEAST	NEDD8-conjugating enzyme UBC12	9545234	A novel protein modification pathway related to the ubiquitin system.

Q6PFL0	MED27_DANRE	Mediator of RNA polymerase II transcription subunit 27	16582438	Differential roles of transcriptional mediator complex subunits Crsp34/Med27, Crsp150/Med14 and Trap100/Med24 during zebrafish retinal development.

Q02793	SKI8_YEAST	Antiviral protein SKI8	9482746	The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex.

Q9R064	GORS2_RAT	Golgi reassembly-stacking protein 2	10487747	GRASP55, a second mammalian GRASP protein involved in the stacking of Golgi cisternae in a cell-free system.

Q54BX5	HSSB_DICDI	Protein hssB	18204858	GBF-dependent family genes morphologically suppress the partially active Dictyostelium STATa strain.

Q9JK91	MLH1_MOUSE	DNA mismatch repair protein Mlh1	8674118	Meiotic pachytene arrest in MLH1-deficient mice.

O94423	MFR1_SCHPO	Meiotic fizzy-related protein 1	15791259	Fission yeast Mes1p ensures the onset of meiosis II by blocking degradation of cyclin Cdc13p.

P25847	MSH2_YEAST	DNA mismatch repair protein MSH2	16702432	Analysis of the proteins involved in the in vivo repair of base-base mismatches and four-base loops formed during meiotic recombination in the yeast Saccharomyces cerevisiae.

Q8BGJ0	ZDH15_MOUSE	Palmitoyltransferase ZDHHC15	15603741	Identification of PSD-95 palmitoylating enzymes.

P43572	EPL1_YEAST	Enhancer of polycomb-like protein 1	10911987	Multiple links between the NuA4 histone acetyltransferase complex and epigenetic control of transcription.

Q96242	CP74A_ARATH	Allene oxide synthase, chloroplastic	8756596	Cloning, molecular and functional characterization of Arabidopsis thaliana allene oxide synthase (CYP 74), the first enzyme of the octadecanoid pathway to jasmonates.

P0CF99	PIMC_MYCTU	GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol dimannoside mannosyltransferase	11964144	Characterization of a putative alpha-mannosyltransferase involved in phosphatidylinositol trimannoside biosynthesis in Mycobacterium tuberculosis.

P41892	CDC7_SCHPO	Cell division control protein 7	9203579	The Spg1p GTPase is an essential, dosage-dependent inducer of septum formation in Schizosaccharomyces pombe.

P00445	SODC_YEAST	Superoxide dismutase [Cu-Zn]	3290902	The copper, zinc-superoxide dismutase gene of Saccharomyces cerevisiae: cloning, sequencing, and biological activity.

O76083	PDE9A_HUMAN	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	9856478	Identification and characterization of a novel cyclic nucleotide phosphodiesterase gene (PDE9A) that maps to 21q22.3: alternative splicing of mRNA transcripts, genomic structure and sequence.

P12532	KCRU_HUMAN	Creatine kinase U-type, mitochondrial	2914937	Isolation and characterization of the gene and cDNA encoding human mitochondrial creatine kinase.

Q9NPA1	KCMB3_HUMAN	Calcium-activated potassium channel subunit beta-3	10585773	Identification of a putative regulatory subunit of a calcium- activated potassium channel in the dup(3q) syndrome region and a related sequence on 22q11.2.

P32851	STX1A_RAT	Syntaxin-1A	1321498	Syntaxin: a synaptic protein implicated in docking of synaptic vesicles at presynaptic active zones.

Q96RR1	PEO1_HUMAN	Twinkle protein, mitochondrial	12975372	TWINKLE has 5' -> 3' DNA helicase activity and is specifically stimulated by mitochondrial single-stranded DNA-binding protein.

Q13769	THOC5_HUMAN	THO complex subunit 5 homolog	15833825	Linking transcriptional elongation and messenger RNA export to metastatic breast cancers.

Q10284	HSP75_SCHPO	Heat shock protein sks2	9161410	A novel HSP70 gene of Schizosaccharomyces pombe that confers K-252a resistance.

P18670	LECA_ARTIN	Agglutinin alpha chain	8673603	A novel mode of carbohydrate recognition in jacalin, a Moraceae plant lectin with a beta-prism fold.

P61586	RHOA_HUMAN	Transforming protein RhoA	12006984	Structural basis for the selective activation of Rho GTPases by Dbl exchange factors.

Q9UTN4	PFS2_SCHPO	Polyadenylation factor subunit 2	15743824	Inactivation of the pre-mRNA cleavage and polyadenylation factor Pfs2 in fission yeast causes lethal cell cycle defects.

Q9NRW1	RAB6B_HUMAN	Ras-related protein Rab-6B	10893188	The small GTPase Rab6B, a novel Rab6 subfamily member, is cell-type specifically expressed and localised to the Golgi apparatus.

Q01976	ADPP_YEAST	ADP-ribose pyrophosphatase	10542272	Studies on the ADP-ribose pyrophosphatase subfamily of the nudix hydrolases and tentative identification of trgB, a gene associated with tellurite resistance.

Q5H8A2	NMS_RAT	Neuromedin-S	15635449	Identification of neuromedin S and its possible role in the mammalian circadian oscillator system.

P43544	SNO3_YEAST	Probable glutamine amidotransferase SNO3	12271461	Functional analysis of yeast gene families involved in metabolism of vitamins B1 and B6.

Q8IWT1	SCN4B_HUMAN	Sodium channel subunit beta-4	12930796	Sodium channel beta4, a new disulfide-linked auxiliary subunit with similarity to beta2.

O94777	DPM2_HUMAN	Dolichol phosphate-mannose biosynthesis regulatory protein	9724629	DPM2 regulates biosynthesis of dolichol phosphate-mannose in mammalian cells: correct subcellular localization and stabilization of DPM1, and binding of dolichol phosphate.

Q9Z1Z9	PDLI7_RAT	PDZ and LIM domain protein 7	19900557	Postsynaptic PDLIM5/Enigma homolog binds SPAR and causes dendritic spine shrinkage.

Q969G3	SMCE1_HUMAN	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1	12192000	REST repression of neuronal genes requires components of the hSWI.SNF complex.

Q6EU39	MADS6_ORYSJ	MADS-box transcription factor 6	10444103	Determination of the motif responsible for interaction between the rice APETALA1/AGAMOUS-LIKE9 family proteins using a yeast two-hybrid system.

Q6V1L5	ARGB_SYNE7	Acetylglutamate kinase	15150219	Interactions between the nitrogen signal transduction protein PII and N-acetyl glutamate kinase in organisms that perform oxygenic photosynthesis.

Q86U42	PABP2_HUMAN	Polyadenylate-binding protein 2	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

Q8UUJ9	SDF1_XENLA	Stromal cell-derived factor 1	17239342	SDF-1 alpha regulates mesendodermal cell migration during frog gastrulation.

O43091	DPS1_SCHPO	Decaprenyl-diphosphate synthase subunit 1	9133618	Analysis of the decaprenyl diphosphate synthase (dps) gene in fission yeast suggests a role of ubiquinone as an antioxidant.

P39936	IF4F2_YEAST	Eukaryotic initiation factor 4F subunit p130	8336723	TIF4631 and TIF4632: two yeast genes encoding the high-molecular- weight subunits of the cap-binding protein complex (eukaryotic initiation factor 4F) contain an RNA recognition motif-like sequence and carry out an essential function.

O43092	OXA12_SCHPO	Mitochondrial inner membrane protein oxa1-2	10712694	The respiratory gene OXA1 has two fission yeast orthologues which together encode a function essential for cellular viability.

P32916	SRPR_YEAST	Signal recognition particle receptor subunit alpha homolog	9679135	A functional GTPase domain, but not its transmembrane domain, is required for function of the SRP receptor beta-subunit.

Q6Z7V2	HS24M_ORYSJ	24.1 kDa heat shock protein, mitochondrial	19135278	Expression analysis of nine rice heat shock protein genes under abiotic stresses and ABA treatment.

Q9BXK5	B2L13_HUMAN	Bcl-2-like protein 13	11262395	Bcl-rambo, a novel Bcl-2 homologue that induces apoptosis via its unique C-terminal extension.

Q07500	NDH2_YEAST	External NADH-ubiquinone oxidoreductase 2, mitochondrial	9733747	The Saccharomyces cerevisiae NDE1 and NDE2 genes encode separate mitochondrial NADH dehydrogenases catalyzing the oxidation of cytosolic NADH.

Q7TMF2	ERI1_MOUSE	3'-5' exoribonuclease 1	19470752	Three proteins of the U7-specific Sm ring function as the molecular ruler to determine the site of 3'-end processing in mammalian histone pre-mRNA.

P53094	MDS3_YEAST	Negative regulator of sporulation MDS3	14562095	Global analysis of protein localization in budding yeast.

Q9P6L8	SRB8_SCHPO	Mediator of RNA polymerase II transcription subunit 12	12738880	TRAP230/ARC240 and TRAP240/ARC250 Mediator subunits are functionally conserved through evolution.

P40512	CSN11_YEAST	Cop9 signalosome complex subunit 11	12186635	Conservation of the COP9/signalosome in budding yeast.

P54098	DPOG1_HUMAN	DNA polymerase subunit gamma-1	8884268	Cloning and characterization of the human mitochondrial DNA polymerase, DNA polymerase gamma.

Q8IY92	SLX4_HUMAN	Structure-specific endonuclease subunit SLX4	19595722	Drosophila MUS312 and the vertebrate ortholog BTBD12 interact with DNA structure-specific endonucleases in DNA repair and recombination.

P16659	SYP_ECOLI	Prolyl-tRNA synthetase	14530268	An isolated class II aminoacyl-tRNA synthetase insertion domain is functional in amino acid editing.

Q05823	RN5A_HUMAN	2-5A-dependent ribonuclease	7514601	Intrinsic molecular activities of the interferon-induced 2-5A- dependent RNase.

Q13363	CTBP1_HUMAN	C-terminal-binding protein 1	7479821	Molecular cloning and characterization of a cellular phosphoprotein that interacts with a conserved C-terminal domain of adenovirus E1A involved in negative modulation of oncogenic transformation.

P70566	TMOD2_RAT	Tropomodulin-2	8886980	N-tropomodulin: a novel isoform of tropomodulin identified as the major binding protein to brain tropomyosin.

Q08777	MCH5_YEAST	Riboflavin transporter MCH5	16204239	The monocarboxylate transporter homolog Mch5p catalyzes riboflavin (vitamin B2) uptake in Saccharomyces cerevisiae.

O09159	MA2B1_MOUSE	Lysosomal alpha-mannosidase	9355733	Lysosomal alpha-mannosidases of mouse tissues: characteristics of the isoenzymes, and cloning and expression of a full-length cDNA.

Q9H093	NUAK2_HUMAN	NUAK family SNF1-like kinase 2	14976552	LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1.

Q9ERI5	JMJD6_MOUSE	Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6	10811223	A receptor for phosphatidylserine-specific clearance of apoptotic cells.

O74354	DNT1_SCHPO	Nucleolar protein dnt1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q24314	VPS18_DROME	Vacuolar protein sorting-associated protein 18 homolog	10549280	A role for the deep orange and carnation eye color genes in lysosomal delivery in Drosophila.

Q13547	HDAC1_HUMAN	Histone deacetylase 1	11006275	Receptor-interacting protein 140 directly recruits histone deacetylases for gene silencing.

P55851	UCP2_HUMAN	Mitochondrial uncoupling protein 2	9054939	Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia.

O59725	YHX5_SCHPO	Uncharacterized protein C3E7.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q54697	PSBI_SYNY3	Photosystem II reaction center protein I	12069591	Proteomic analysis of a highly active photosystem II preparation from the cyanobacterium Synechocystis sp. PCC 6803 reveals the presence of novel polypeptides.

P55861	MCM2_XENLA	DNA replication licensing factor mcm2	9214647	Licensing of DNA replication by a multi-protein complex of MCM/P1 proteins in Xenopus eggs.

Q9TTE1	SPA31_BOVIN	Serpin A3-1	10567388	Molecular cloning of endopin 1, a novel serpin localized to neurosecretory vesicles of chromaffin cells. Inhibition of basic residue-cleaving proteases by endopin 1.

O35826	GLCNE_RAT	Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase	9305888	A bifunctional enzyme catalyzes the first two steps in N- acetylneuraminic acid biosynthesis of rat liver. Molecular cloning and functional expression of UDP-N-acetyl-glucosamine 2-epimerase/N- acetylmannosamine kinase.

P32591	SWI3_YEAST	SWI/SNF complex subunit SWI3	1339306	Characterization of the yeast SWI1, SWI2, and SWI3 genes, which encode a global activator of transcription.

P28907	CD38_HUMAN	ADP-ribosyl cyclase 1	8253715	Synthesis and hydrolysis of cyclic ADP-ribose by human leukocyte antigen CD38 and inhibition of the hydrolysis by ATP.

Q91ZK4	DMBX1_MOUSE	Diencephalon/mesencephalon homeobox protein 1	15890343	Functional analysis of transcriptional repressor Otx3/Dmbx1.

O16850	FOXO_CAEEL	Forkhead box protein O	18762027	A 13C isotope labeling strategy reveals the influence of insulin signaling on lipogenesis in C. elegans.

P30622	CLIP1_HUMAN	CAP-Gly domain-containing linker protein 1	1600942	Restin: a novel intermediate filament-associated protein highly expressed in the Reed-Sternberg cells of Hodgkin's disease.

Q9IAV3	HHEX_DANRE	Hematopoietically-expressed homeobox protein hhex	11003831	Hhex and scl function in parallel to regulate early endothelial and blood differentiation in zebrafish.

P25573	MGR1_YEAST	Mitochondrial inner membrane i-AAA protease supercomplex subunit MGR1	18843051	Mgr3p and Mgr1p are adaptors for the mitochondrial i-AAA protease complex.

Q02734	SIAT6_RAT	CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase	1400416	Primary structure of Gal beta 1,3(4)GlcNAc alpha 2,3- sialyltransferase determined by mass spectrometry sequence analysis and molecular cloning. Evidence for a protein motif in the sialyltransferase gene family.

Q9C5C2	BGL37_ARATH	Myrosinase 2	7766881	The myrosinase gene family in Arabidopsis thaliana: gene organization, expression and evolution.

P53833	POP3_YEAST	Ribonucleases P/MRP protein subunit POP3	9029160	Pop3p is essential for the activity of the RNase MRP and RNase P ribonucleoproteins in vivo.

P68871	HBB_HUMAN	Hemoglobin subunit beta	1540659	Structure of the EF corner favors deamidation of asparaginyl residues in hemoglobin: the example of Hb La Roche-sur-Yon [beta 81 (EF5) Leu-->His].

O15511	ARPC5_HUMAN	Actin-related protein 2/3 complex subunit 5	9359840	Mammalian actin-related protein 2/3 complex localizes to regions of lamellipodial protrusion and is composed of evolutionarily conserved proteins.

O59757	SPC7_SCHPO	Kinetochore protein spc7	16079914	Molecular analysis of kinetochore architecture in fission yeast.

Q9P7B7	YK24_SCHPO	Uncharacterized protein C140.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UER7	DAXX_HUMAN	Death domain-associated protein 6	11483955	TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation.

P78562	PHEX_HUMAN	Phosphate-regulating neutral endopeptidase	9070861	Expression and cloning of the human X-linked hypophosphatemia gene cDNA.

P97401	SFRP3_MOUSE	Secreted frizzled-related protein 3	9178261	Fritz: a secreted frizzled-related protein that inhibits Wnt activity.

P32563	VPH1_YEAST	V-type proton ATPase subunit a, vacuolar isoform	8798414	Site-directed mutagenesis of the 100-kDa subunit (Vph1p) of the yeast vacuolar (H+)-ATPase.

O76512	RENT1_CAEEL	Regulator of nonsense transcripts 1	10454541	SMG-2 is a phosphorylated protein required for mRNA surveillance in Caenorhabditis elegans and related to Upf1p of yeast.

Q9C108	YKT1_SCHPO	Uncharacterized protein PB1E7.01c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q70PY2	PGSB1_DROME	Peptidoglycan-recognition protein SB1	11106397	A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster.

Q6DR24	Y3795_ARATH	Uncharacterized protein At3g17950	15618630	Identification of three clones which commonly interact with the kinase domains of highly homologous two receptor-like kinases, RLK902 and RKL1.

Q96Q42	ALS2_HUMAN	Alsin	17239822	ALS2CL, a novel ALS2-interactor, modulates ALS2-mediated endosome dynamics.

P0AFF0	NUON_ECOLI	NADH-quinone oxidoreductase subunit N	12718520	Mutagenesis of subunit N of the Escherichia coli complex I. Identification of the initiation codon and the sensitivity of mutants to decylubiquinone.

Q92956	TNR14_HUMAN	Tumor necrosis factor receptor superfamily member 14	11511370	Herpes simplex virus glycoprotein D bound to the human receptor HveA.

Q8H0T4	UPL2_ARATH	E3 ubiquitin-protein ligase UPL2	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

Q04418	RBA50_YEAST	RNA polymerase II-associated protein RBA50	15282305	RPAP1, a novel human RNA polymerase II-associated protein affinity purified with recombinant wild-type and mutated polymerase subunits.

P17861	XBP1_HUMAN	X-box-binding protein 1	2321018	A new member of the leucine zipper class of proteins that binds to the HLA DR alpha promoter.

P36057	SRPB_YEAST	Signal recognition particle receptor subunit beta	12654246	Structural basis for the function of the beta subunit of the eukaryotic signal recognition particle receptor.

O15296	LX15B_HUMAN	Arachidonate 15-lipoxygenase B	9177185	Discovery of a second 15S-lipoxygenase in humans.

O95644	NFAC1_HUMAN	Nuclear factor of activated T-cells, cytoplasmic 1	8702849	Characterization of a new isoform of the NFAT (nuclear factor of activated T cells) gene family member NFATc.

Q9JKT8	TR114_RAT	Taste receptor type 2 member 114	10761934	A novel family of mammalian taste receptors.

Q8K1S5	KLF11_MOUSE	Krueppel-like factor 11	15607700	Functional study of transcription factor KLF11 by targeted gene inactivation.

Q9LSD6	ARP2_ARATH	Actin-related protein 2	12837952	Mutations in actin-related proteins 2 and 3 affect cell shape development in Arabidopsis.

Q6UWE0	LRSM1_HUMAN	E3 ubiquitin-protein ligase LRSAM1	15256501	Tal, a Tsg101-specific E3 ubiquitin ligase, regulates receptor endocytosis and retrovirus budding.

Q9LTS3	CKX3_ARATH	Cytokinin dehydrogenase 3	14555694	Cytokinin-deficient transgenic Arabidopsis plants show multiple developmental alterations indicating opposite functions of cytokinins in the regulation of shoot and root meristem activity.

Q10213	SRS2_SCHPO	ATP-dependent DNA helicase srs2	14993467	The involvement of Srs2 in post-replication repair and homologous recombination in fission yeast.

P38741	RIM4_YEAST	Meiotic activator RIM4	11713679	RIM4 encodes a meiotic activator required for early events of meiosis in Saccharomyces cerevisiae.

Q9WVP6	PAPOB_MOUSE	Poly(A) polymerase beta	11150526	An intronless gene encoding a poly(A) polymerase is specifically expressed in testis.

Q4VSI4	UBP7_RAT	Ubiquitin carboxyl-terminal hydrolase 7	16111684	HAUSP, a deubiquitinating enzyme for p53, is polyubiquitinated, polyneddylated, and dimerized.

Q54MY9	MKCA_DICDI	Probable serine/threonine-protein kinase mkcA	8986798	Developmental signal transduction pathways uncovered by genetic suppressors.

Q00266	METK1_HUMAN	S-adenosylmethionine synthase isoform type-1	1772450	Molecular cloning and nucleotide sequence of cDNA encoding the human liver S-adenosylmethionine synthetase.

Q08651	YO246_YEAST	Uncharacterized oxidoreductase YOR246C	14562095	Global analysis of protein localization in budding yeast.

O94650	HUB1_SCHPO	Ubiquitin-like modifier hub1	15620657	Ubiquitin-like protein Hub1 is required for pre-mRNA splicing and localization of an essential splicing factor in fission yeast.

Q04458	HFD1_YEAST	Putative fatty aldehyde dehydrogenase HFD1	14562095	Global analysis of protein localization in budding yeast.

Q99N50	SYTL2_MOUSE	Synaptotagmin-like protein 2	18266782	Slp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapse.

P55068	PGCB_RAT	Brevican core protein	7592978	Brevican, a chondroitin sulfate proteoglycan of rat brain, occurs as secreted and cell surface glycosylphosphatidylinositol-anchored isoforms.

Q61086	FZD3_MOUSE	Frizzled-3	16687519	Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals.

O00115	DNS2A_HUMAN	Deoxyribonuclease-2-alpha	9714827	Molecular cloning and characterization of human and murine DNase II.

P26188	MGMT_YEAST	Methylated-DNA--protein-cysteine methyltransferase	1641326	The Saccharomyces cerevisiae MGT1 DNA repair methyltransferase gene: its promoter and entire coding sequence, regulation and in vivo biological functions.

O95450	ATS2_HUMAN	A disintegrin and metalloproteinase with thrombospondin motifs 2	10417273	Human Ehlers-Danlos syndrome type VII C and bovine dermatosparaxis are caused by mutations in the procollagen I N-proteinase gene.

Q99332	HPH1_YEAST	Protein HPH1	12514182	Bipartite signals mediate subcellular targeting of tail-anchored membrane proteins in Saccharomyces cerevisiae.

Q9UBC3	DNM3B_HUMAN	DNA (cytosine-5)-methyltransferase 3B	10647011	Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene.

P08729	K2C7_HUMAN	Keratin, type II cytoskeletal 7	12072504	Translational regulation of human papillomavirus type 16 E7 mRNA by the peptide SEQIKA, shared by rabbit alpha(1)-globin and human cytokeratin 7.

P84046	H4_CHITH	Histone H4	1769271	The organization, localization and nucleotide sequence of the histone genes of the midge Chironomus thummi.

Q05949	BUR2_YEAST	Protein BUR2	10982824	BUR1 and BUR2 encode a divergent cyclin-dependent kinase-cyclin complex important for transcription in vivo.

Q9SCR2	KRP2_ARATH	Cyclin-dependent kinase inhibitor 2	16376885	Arabidopsis KRPs have distinct inhibitory activity toward cyclin D2- associated kinases, including plant-specific B-type cyclin-dependent kinase.

Q9UNT1	RBL2B_HUMAN	Rab-like protein 2B	10444334	Two novel human RAB genes with near identical sequence each map to a telomere-associated region: the subtelomeric region of 22q13.3 and the ancestral telomere band 2q13.

Q9DF49	IRS2A_XENLA	Insulin receptor substrate 2-A	9717835	A novel insulin receptor substrate protein, xIRS-u, potentiates insulin signaling: functional importance of its pleckstrin homology domain.

P70595	NGN1_RAT	Neurogenin-1	8858147	Identification of neurogenin, a vertebrate neuronal determination gene.

O95071	UBR5_HUMAN	E3 ubiquitin-protein ligase UBR5	10030672	Identification of a human HECT family protein with homology to the Drosophila tumor suppressor gene hyperplastic discs.

P45983	MK08_HUMAN	Mitogen-activated protein kinase 8	8137421	JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain.

Q9TYV2	SMSR2_CAEEL	Sphingomyelin synthase-related 2	14685263	Identification of a family of animal sphingomyelin synthases.

Q9NY61	AATF_HUMAN	Protein AATF	12429849	Functional proteomic analysis of human nucleolus.

P25303	SCJ1_YEAST	DnaJ-related protein SCJ1	11381090	Molecular chaperones in the yeast endoplasmic reticulum maintain the solubility of proteins for retrotranslocation and degradation.

Q14152	EIF3A_HUMAN	Eukaryotic translation initiation factor 3 subunit A	17322308	Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry.

O75691	UTP20_HUMAN	Small subunit processome component 20 homolog	17498821	Human 1A6/DRIM, the homolog of yeast Utp20, functions in the 18S rRNA processing.

Q24368	ISWI_DROME	Chromatin-remodeling complex ATPase chain Iswi	8521502	ISWI, a member of the SWI2/SNF2 ATPase family, encodes the 140 kDa subunit of the nucleosome remodeling factor.

P55053	FABP5_RAT	Fatty acid-binding protein, epidermal	8723767	Fatty acid binding protein is induced in neurons of the dorsal root ganglia after peripheral nerve injury.

P19235	EPOR_HUMAN	Erythropoietin receptor	2163696	Human erythropoietin receptor: cloning, expression, and biologic characterization.

Q0WPQ2	ETR2_ARATH	Ethylene receptor 2	9576967	ETR2 is an ETR1-like gene involved in ethylene signaling in Arabidopsis.

Q9ES83	POPD1_MOUSE	Blood vessel epicardial substance	18541910	Bves directly interacts with GEFT, and controls cell shape and movement through regulation of Rac1/Cdc42 activity.

O95810	SDPR_HUMAN	Serum deprivation-response protein	18332105	MURC, a muscle-restricted coiled-coil protein that modulates the Rho/ROCK pathway, induces cardiac dysfunction and conduction disturbance.

O95271	TNKS1_HUMAN	Tankyrase-1	11739745	Role for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeres.

O23116	EIL3_ARATH	ETHYLENE INSENSITIVE 3-like 3 protein	9215635	Activation of the ethylene gas response pathway in Arabidopsis by the nuclear protein ETHYLENE-INSENSITIVE3 and related proteins.

Q6NYC1	JMJD6_HUMAN	Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6	17947579	JMJD6 is a histone arginine demethylase.

P38904	SPP41_YEAST	Protein SPP41	8005438	Extragenic suppressors of Saccharomyces cerevisiae prp4 mutations identify a negative regulator of PRP genes.

Q6NWL1	PD10B_DANRE	Programmed cell death protein 10-B	19370760	Functional analyses of human and zebrafish 18-amino acid in-frame deletion pave the way for domain mapping of the cerebral cavernous malformation 3 protein.

Q9EQZ7	RIMS2_MOUSE	Regulating synaptic membrane exocytosis protein 2	11056535	cAMP-GEFII is a direct target of cAMP in regulated exocytosis.

Q92611	EDEM1_HUMAN	ER degradation-enhancing alpha-mannosidase-like 1	19524542	EDEM1 recognition and delivery of misfolded proteins to the SEL1L- containing ERAD complex.

O15127	SCAM2_HUMAN	Secretory carrier-associated membrane protein 2	16870614	Subcellular redistribution of the serotonin transporter by secretory carrier membrane protein 2.

O95969	SG1D2_HUMAN	Secretoglobin family 1D member 2	10066439	Lipophilins: human peptides homologous to rat prostatein.

O14745	NHRF1_HUMAN	Na(+)/H(+) exchange regulatory cofactor NHE-RF1	11285285	Identification of EPI64, a TBC/rabGAP domain-containing microvillar protein that binds to the first PDZ domain of EBP50 and E3KARP.

Q8TAT5	NEIL3_HUMAN	Endonuclease 8-like 3	12433996	Human DNA glycosylases of the bacterial Fpg/MutM superfamily: an alternative pathway for the repair of 8-oxoguanine and other oxidation products in DNA.

P15179	SYDM_YEAST	Aspartyl-tRNA synthetase, mitochondrial	2668951	Homology of aspartyl- and lysyl-tRNA synthetases.

Q16773	KAT1_HUMAN	Kynurenine--oxoglutarate transaminase 1	15364907	Crystal structure of human kynurenine aminotransferase I.

P31135	POTH_ECOLI	Putrescine transport system permease protein potH	8416922	Characteristics of the operon for a putrescine transport system that maps at 19 minutes on the Escherichia coli chromosome.

Q9LIC7	PR1F4_ARATH	PRA1 family protein F4	18583532	The PRA1 gene family in Arabidopsis.

P18265	GSK3A_RAT	Glycogen synthase kinase-3 alpha	2164470	Molecular cloning and expression of glycogen synthase kinase-3/factor A.

P21651	RE107_YEAST	Recombination protein 107	16783010	Saccharomyces cerevisiae Mer2, Mei4 and Rec114 form a complex required for meiotic double-strand break formation.

P00957	SYA_ECOLI	Alanyl-tRNA synthetase	12554667	Elucidation of tRNA-dependent editing by a class II tRNA synthetase and significance for cell viability.

P32347	DCUP_YEAST	Uroporphyrinogen decarboxylase	14562095	Global analysis of protein localization in budding yeast.

Q9DBK0	ACO12_MOUSE	Acyl-coenzyme A thioesterase 12	12545200	Mouse cytosolic acetyl-CoA hydrolase, a novel candidate for a key enzyme involved in fat metabolism: cDNA cloning, sequencing and functional expression.

P05749	RL22A_YEAST	60S ribosomal protein L22-A	6814480	Isolation of seventeen proteins and amino-terminal amino acid sequences of eight proteins from cytoplasmic ribosomes of yeast.

O35613	DAXX_MOUSE	Death domain-associated protein 6	11799127	The interaction of Pax5 (BSAP) with Daxx can result in transcriptional activation in B cells.

Q42541	UBC13_ARATH	Ubiquitin-conjugating enzyme E2 13	16339806	Genome analysis and functional characterization of the E2 and RING- type E3 ligase ubiquitination enzymes of Arabidopsis.

P28629	ADIA_ECOLI	Biodegradative arginine decarboxylase	8383109	Nucleotide sequence of the adi gene, which encodes the biodegradative acid-induced arginine decarboxylase of Escherichia coli.

Q9LD90	DKC1_ARATH	H/ACA ribonucleoprotein complex subunit 4	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

Q06327	LOX1_ARATH	Lipoxygenase 1	17369372	Oxylipins produced by the 9-lipoxygenase pathway in Arabidopsis regulate lateral root development and defense responses through a specific signaling cascade.

P04438	HV208_HUMAN	Ig heavy chain V-II region SESS	6089186	Rearranged immunoglobulin heavy chain variable region (VH) pseudogene that deletes the second complementarity-determining region.

O15119	TBX3_HUMAN	T-box transcription factor TBX3	9207801	Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome.

P51692	STA5B_HUMAN	Signal transducer and activator of transcription 5B	9989503	Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgamma-mediated signaling.

P42699	PLAS2_ARATH	Plastocyanin major isoform, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

O94364	YHOH_SCHPO	Uncharacterized serine-rich protein C428.17c	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

Q87P32	VOPS_VIBPA	Adenosine monophosphate-protein transferase vopS	19039103	AMPylation of Rho GTPases by Vibrio VopS disrupts effector binding and downstream signaling.

Q01217	ARG56_YEAST	Protein ARG5,6, mitochondrial	1851947	Characterization of the yeast ARG5,6 gene: determination of the nucleotide sequence, analysis of the control region and of ARG5,6 transcript.

P15108	HSC82_YEAST	ATP-dependent molecular chaperone HSC82	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P32527	ZUO1_YEAST	Zuotin	11274393	RAC, a stable ribosome-associated complex in yeast formed by the DnaK-DnaJ homologs Ssz1p and zuotin.

P12273	PIP_HUMAN	Prolactin-inducible protein	2013294	Primary structure of a new actin-binding protein from human seminal plasma.

Q9M0N8	MZT1B_ARATH	Mitotic-spindle organizing protein 1B	18178112	Identification of a novel small Arabidopsis protein interacting with gamma-tubulin complex protein 3.

P01108	MYC_MOUSE	Myc proto-oncogene protein	8521822	Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation.

P70611	DOC2A_RAT	Double C2-like domain-containing protein alpha	18354201	Doc2 alpha and Munc13-4 regulate Ca(2+) -dependent secretory lysosome exocytosis in mast cells.

P40454	PTPA1_YEAST	Serine/threonine-protein phosphatase 2A activator 1	11262194	The Saccharomyces cerevisiae phosphotyrosyl phosphatase activator proteins are required for a subset of the functions disrupted by protein phosphatase 2A mutations.

P13185	KIN1_YEAST	Serine/threonine protein kinase KIN1	1652871	The product of the KIN1 locus in Saccharomyces cerevisiae is a serine/threonine-specific protein kinase.

P32480	HIR2_YEAST	Protein HIR2	16303565	Replication-independent histone deposition by the HIR complex and Asf1.

Q9UPS6	SET1B_HUMAN	Histone-lysine N-methyltransferase SETD1B	17355966	Identification and characterization of the human Set1B histone H3- Lys4 methyltransferase complex.

P41777	NOLC1_RAT	Nucleolar and coiled-body phosphoprotein 1	1623516	Nopp140 shuttles on tracks between nucleolus and cytoplasm.

Q0IH87	PAX3B_XENLA	Paired box protein Pax-3-B	15691759	Msx1 and Pax3 cooperate to mediate FGF8 and WNT signals during Xenopus neural crest induction.

O43541	SMAD6_HUMAN	Mothers against decapentaplegic homolog 6	9436979	Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor.

P57735	RAB25_HUMAN	Ras-related protein Rab-25	17925226	Rab25 associates with alpha5beta1 integrin to promote invasive migration in 3D microenvironments.

P78560	CRADD_HUMAN	Death domain-containing protein CRADD	16652156	Functional connection between p53 and caspase-2 is essential for apoptosis induced by DNA damage.

P38788	SSZ1_YEAST	Ribosome-associated complex subunit SSZ1	15456889	The ribosome-bound chaperones RAC and Ssb1/2p are required for accurate translation in Saccharomyces cerevisiae.

Q9UJC3	HOOK1_HUMAN	Protein Hook homolog 1	18799622	An FTS/Hook/p107(FHIP) complex interacts with and promotes endosomal clustering by the homotypic vacuolar protein sorting complex.

O35613	DAXX_MOUSE	Death domain-associated protein 6	12529400	Homeodomain-interacting protein kinase 1 modulates Daxx localization, phosphorylation, and transcriptional activity.

P54349	IL12A_BOVIN	Interleukin-12 subunit alpha	7727547	Enzymatic amplification and molecular cloning of cDNA encoding the small and large subunits of bovine interleukin 12.

O60547	GMDS_HUMAN	GDP-mannose 4,6 dehydratase	9525924	Molecular cloning of human GDP-mannose 4,6-dehydratase and reconstitution of GDP-fucose biosynthesis in vitro.

Q9GPZ7	FTSZB_DICDI	Mitochondrial division protein fszB	14665465	Two Dictyostelium orthologs of the prokaryotic cell division protein FtsZ localize to mitochondria and are required for the maintenance of normal mitochondrial morphology.

P27049	BTG2_RAT	Protein BTG2	11237868	Mitogen-stimulated TIS21 protein interacts with a protein-kinase- Calpha-binding protein rPICK1.

P42836	PFA3_YEAST	Palmitoyltransferase PFA3	16186255	The vacuolar DHHC-CRD protein Pfa3p is a protein acyltransferase for Vac8p.

Q9H461	FZD8_HUMAN	Frizzled-8	11295046	Molecular cloning and characterization of human Frizzled-8 gene on chromosome 10p11.2.

P16871	IL7RA_HUMAN	Interleukin-7 receptor subunit alpha	2317865	Cloning of the human and murine interleukin-7 receptors: demonstration of a soluble form and homology to a new receptor superfamily.

P37013	NORR_ECOLI	Anaerobic nitric oxide reductase transcription regulator norR	11751865	Flavorubredoxin, an inducible catalyst for nitric oxide reduction and detoxification in Escherichia coli.

O74869	NIC1_SCHPO	High-affinity nickel transport protein nic1	10748059	Nic1p, a relative of bacterial transition metal permeases in Schizosaccharomyces pombe, provides nickel ion for urease biosynthesis.

O88680	C3AR_CAVPO	C3a anaphylatoxin chemotactic receptor	9743361	Molecular cloning of two isoforms of the guinea pig C3a anaphylatoxin receptor: alternative splicing in the large extracellular loop.

Q8WZK2	MCD4_SCHPO	GPI ethanolamine phosphate transferase 1	11297516	Its8, a fission yeast homolog of Mcd4 and Pig-n, is involved in GPI anchor synthesis and shares an essential function with calcineurin in cytokinesis.

O13715	MUG5_SCHPO	Meiotically up-regulated gene 5 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9XVS7	NXF1_CAEEL	Nuclear RNA export factor 1	11142376	The mRNA export in Caenorhabditis elegans is mediated by Ce-NXF-1, an ortholog of human TAP/NXF and Saccharomyces cerevisiae Mex67p.

P25639	YCV1_YEAST	Uncharacterized membrane protein YCR061W	14562095	Global analysis of protein localization in budding yeast.

Q92585	MAML1_HUMAN	Mastermind-like protein 1	17317671	The notch regulator MAML1 interacts with p53 and functions as a coactivator.

P39014	MET30_YEAST	F-box protein MET30	15689486	The yeast ubiquitin ligase SCFMet30 regulates heavy metal response.

P20649	PMA1_ARATH	ATPase 1, plasma membrane-type	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

Q9P241	AT10D_HUMAN	Probable phospholipid-transporting ATPase VD	12532265	Characterization of a putative type IV aminophospholipid transporter P-type ATPase.

Q9FFY9	TRP4_ARATH	Telomere repeat-binding protein 4	19962994	PAH-domain-specific interactions of the Arabidopsis transcription coregulator SIN3-LIKE1 (SNL1) with telomere-binding protein 1 and ALWAYS EARLY2 Myb-DNA binding factors.

Q54CH1	ADCA_DICDI	Arrestin domain-containing protein A	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

Q10445	RHP41_SCHPO	DNA repair protein rhp41	12807767	Repair of damaged and mismatched DNA by the XPC homologues Rhp41 and Rhp42 of fission yeast.

P47103	CYP7_YEAST	Peptidyl-prolyl cis-trans isomerase CYP7	8873448	Identification of two CyP-40-like cyclophilins in Saccharomyces cerevisiae, one of which is required for normal growth.

Q9H4S2	GSX1_HUMAN	GS homeobox 1	11731616	Homeobox protein Gsh-1-dependent regulation of the rat GHRH gene promoter.

O00453	LST1_HUMAN	Leukocyte-specific transcript 1 protein	7590964	Cloning and genomic characterization of LST1: a new gene in the human TNF region.

Q9BXW9	FACD2_HUMAN	Fanconi anemia group D2 protein	12093742	FANCE: the link between Fanconi anaemia complex assembly and activity.

P81910	OR22B_DROME	Odorant receptor 22b	10069338	A novel family of divergent seven-transmembrane proteins: candidate odorant receptors in Drosophila.

Q23AS2	TTL3E_TETTH	Tubulin glycylase 3E	19531357	TTLL3 Is a tubulin glycine ligase that regulates the assembly of cilia.

O04719	P2C77_ARATH	Protein phosphatase 2C 77	19769575	Closely related receptor complexes differ in their ABA selectivity and sensitivity.

P40307	PSB2_RAT	Proteasome subunit beta type-2	16988215	Differential expression of genes encoding constitutive and inducible 20S proteasomal core subunits in the testis and epididymis of theophylline- or 1,3-dinitrobenzene-exposed rats.

Q9SEZ7	CIPKG_ARATH	CBL-interacting serine/threonine-protein kinase 16	17898163	A protein phosphorylation/dephosphorylation network regulates a plant potassium channel.

P17610	YPT3_SCHPO	GTP-binding protein ypt3	12181359	Role of the Rab GTP-binding protein Ypt3 in the fission yeast exocytic pathway and its connection to calcineurin function.

O74803	RHP23_SCHPO	UV excision repair protein rhp23	10652237	Identification and characterization of the rhp23(+) DNA repair gene in Schizosaccharomyces pombe.

Q2QW53	MAD13_ORYSJ	MADS-box transcription factor 13	12395189	Ovule-specific MADS-box proteins have conserved protein-protein interactions in monocot and dicot plants.

O15466	SIA8E_HUMAN	Alpha-2,8-sialyltransferase 8E	9199191	Molecular cloning and expression of human alpha2,8-sialyltransferase (hST8Sia V).

P85210	CECD_GALME	Cecropin-D-like peptide	17194500	Purification and characterization of eight peptides from Galleria mellonella immune hemolymph.

Q9LV01	ETOL2_ARATH	ETO1-like protein 2	15118728	Regulation of ethylene gas biosynthesis by the Arabidopsis ETO1 protein.

O60950	GOL_DICDI	Golvesin	11229601	Golvesin-GFP fusions as distinct markers for Golgi and post-Golgi vesicles in Dictyostelium cells.

Q96RE7	NACC1_HUMAN	Nucleus accumbens-associated protein 1	17130457	A BTB/POZ protein, NAC-1, is related to tumor recurrence and is essential for tumor growth and survival.

Q9H9C1	VIPAR_HUMAN	VPS33B-interacting protein	20190753	Mutations in VIPAR cause an arthrogryposis, renal dysfunction and cholestasis syndrome phenotype with defects in epithelial polarization.

P84713	CMO1_CONMO	Toxin Mo1659	15081394	A novel 13 residue acyclic peptide from the marine snail, Conus monile, targets potassium channels.

P19880	YAP1_YEAST	AP-1-like transcription factor YAP1	12582119	Yap1 accumulates in the nucleus in response to carbon stress in Saccharomyces cerevisiae.

P70056	FOXH1_XENLA	Forkhead box protein H1	10572039	FAST-1 is a key maternal effector of mesoderm inducers in the early Xenopus embryo.

P24058	ARLY2_ANAPL	Argininosuccinate lyase	11698398	Mutational analysis of duck delta 2 crystallin and the structure of an inactive mutant with bound substrate provide insight into the enzymatic mechanism of argininosuccinate lyase.

Q42371	ERECT_ARATH	LRR receptor-like serine/threonine-protein kinase ERECTA	14617092	ERECTA, an LRR receptor-like kinase protein controlling development pleiotropically affects resistance to bacterial wilt.

Q9ESQ7	PSD1_RAT	PH and SEC7 domain-containing protein 1	11834294	Localization of mRNAs for subfamily of guanine nucleotide-exchange proteins (GEP) for ARFs (ADP-ribosylation factors) in the brain of developing and mature rats under normal and postaxotomy conditions.

O75381	PEX14_HUMAN	Peroxisomal membrane protein PEX14	9653144	Identification of a human PTS1 receptor docking protein directly required for peroxisomal protein import.

Q9P1T7	MDFIC_HUMAN	MyoD family inhibitor domain-containing protein	11139147	Sequence requirement for the nucleolar localization of human I-mfa domain-containing protein (HIC p40).

Q99941	ATF6B_HUMAN	Cyclic AMP-dependent transcription factor ATF-6 beta	8586413	A novel Creb family gene telomeric of HLA-DRA in the HLA complex.

P22943	HSP12_YEAST	12 kDa heat shock protein	11816034	HSP12 is essential for biofilm formation by a Sardinian wine strain of Saccharomyces cerevisiae.

Q9ASS4	Y5838_ARATH	Probably inactive leucine-rich repeat receptor-like protein kinase At5g48380	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P40467	ASG1_YEAST	Activator of stress genes 1	14562095	Global analysis of protein localization in budding yeast.

P22134	MAG_YEAST	DNA-3-methyladenine glycosylase	2265619	Cloning and expression in Escherichia coli of a gene for an alkylbase DNA glycosylase from Saccharomyces cerevisiae; a homologue to the bacterial alkA gene.

P49711	CTCF_HUMAN	Transcriptional repressor CTCF	18654629	The insulator binding protein CTCF positions 20 nucleosomes around its binding sites across the human genome.

Q61144	PSN2_MOUSE	Presenilin-2	8940094	Requirement of the familial Alzheimer's disease gene PS2 for apoptosis. Opposing effect of ALG-3.

Q9UM54	MYO6_HUMAN	Myosin-VI	16949370	Nuclear myosin VI enhances RNA polymerase II-dependent transcription.

Q9QYB2	DACH1_MOUSE	Dachshund homolog 1	14628042	Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis.

P51673	RABP2_RAT	Cellular retinoic acid-binding protein 2	7750498	Inducible expression of cellular retinoic acid-binding protein II in rat ovary: gonadotropin regulation during luteal development.

Q8N8Q8	COX18_HUMAN	Mitochondrial inner membrane protein COX18	16212937	hCOX18 and hCOX19: two human genes involved in cytochrome c oxidase assembly.

Q04412	AGE1_YEAST	ADP-ribosylation factor GTPase-activating protein effector protein 1	9677411	A family of Arf effectors defined as suppressors of the loss of Arf function in the yeast Saccharomyces cerevisiae.

Q71MB6	SO4C1_RAT	Solute carrier organic anion transporter family member 4C1	14993604	Isolation and characterization of a digoxin transporter and its rat homologue expressed in the kidney.

Q09990	LIN23_CAEEL	F-box/WD repeat-containing protein lin-23	11060233	The Caenorhabditis elegans F-box/WD-repeat protein lin-23 functions to limit cell division during development.

P63000	RAC1_HUMAN	Ras-related C3 botulinum toxin substrate 1	2674130	Rac, a novel ras-related family of proteins that are botulinum toxin substrates.

Q8N122	RPTOR_HUMAN	Regulatory-associated protein of mTOR	12150926	Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action.

P53061	ZIP2_YEAST	Protein ZIP2	10943844	Zip3 provides a link between recombination enzymes and synaptonemal complex proteins.

Q12071	VPS54_YEAST	Vacuolar protein sorting-associated protein 54	11689439	An effector of Ypt6p binds the SNARE Tlg1p and mediates selective fusion of vesicles with late Golgi membranes.

Q9NYA1	SPHK1_HUMAN	Sphingosine kinase 1	10863092	Human sphingosine kinase: molecular cloning, functional characterization and tissue distribution.

O08967	CYH3_MOUSE	Cytohesin-3	9072969	Signaling by phosphoinositide-3,4,5-trisphosphate through proteins containing pleckstrin and Sec7 homology domains.

P61371	ISL1_HUMAN	Insulin gene enhancer protein ISL-1	7912209	Isolation of the human LIM/homeodomain gene islet-1 and identification of a simple sequence repeat polymorphism.

Q9FQ09	KU80_ARATH	ATP-dependent DNA helicase 2 subunit KU80	16380432	Involvement of KU80 in T-DNA integration in plant cells.

Q9SXP7	LIPB_ARATH	Octanoyltransferase	11427685	Lipoic acid metabolism in Arabidopsis thaliana: cloning and characterization of a cDNA encoding lipoyltransferase.

P30872	SSR1_HUMAN	Somatostatin receptor type 1	1346068	Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney.

Q9NS56	TOPRS_HUMAN	E3 ubiquitin-protein ligase Topors	18077445	Ubiquitination by TOPORS regulates the prostate tumor suppressor NKX3.1.

O75335	LIPA4_HUMAN	Liprin-alpha-4	9624153	Liprins, a family of LAR transmembrane protein-tyrosine phosphatase- interacting proteins.

Q08426	ECHP_HUMAN	Peroxisomal bifunctional enzyme	8188243	cDNA cloning of the human peroxisomal enoyl-CoA hydratase: 3- hydroxyacyl-CoA dehydrogenase bifunctional enzyme and localization to chromosome 3q26.3-3q28: a free left Alu Arm is inserted in the 3' noncoding region.

Q9NP95	FGF20_HUMAN	Fibroblast growth factor 20	10913340	Molecular cloning and characterization of human FGF-20 on chromosome 8p21.3-p22.

Q940Z2	ARP5_ARATH	Actin-related protein 5	11891255	Arabidopsis contains ancient classes of differentially expressed actin-related protein genes.

Q9M384	SCR_ARATH	Protein SCARECROW	10631180	Molecular analysis of SCARECROW function reveals a radial patterning mechanism common to root and shoot.

Q14151	SAFB2_HUMAN	Scaffold attachment factor B2	12660241	SAFB2, a new scaffold attachment factor homolog and estrogen receptor corepressor.

Q9Y6R4	M3K4_HUMAN	Mitogen-activated protein kinase kinase kinase 4	9305639	A human homolog of the yeast Ssk2/Ssk22 MAP kinase kinase kinases, MTK1, mediates stress-induced activation of the p38 and JNK pathways.

P01719	LV501_HUMAN	Ig lambda chain V-V region DEL	4452363	A new subgroup of human L-chains of the lambda-type. Primary structure of Bence-Jones protein DEL.

P51810	GP143_HUMAN	G-protein coupled receptor 143	10471510	Ocular albinism: evidence for a defect in an intracellular signal transduction system.

Q02985	FHR3_HUMAN	Complement factor H-related protein 3	8428964	A novel short consensus repeat-containing molecule is related to human complement factor H.

Q9URV9	SRX1_SCHPO	Sulfiredoxin	15824112	Oxidation of a eukaryotic 2-Cys peroxiredoxin is a molecular switch controlling the transcriptional response to increasing levels of hydrogen peroxide.

P0AA39	RLUC_ECOLI	Ribosomal large subunit pseudouridine synthase C	9660827	The rluC gene of Escherichia coli codes for a pseudouridine synthase that is solely responsible for synthesis of pseudouridine at positions 955, 2504, and 2580 in 23 S ribosomal RNA.

Q08I43	ERI1_SCHPO	3'-5' exonuclease eri1	18438419	The exonuclease ERI-1 has a conserved dual role in 5.8S rRNA processing and RNAi.

Q9CKP2	SLYD_PASMU	FKBP-type peptidyl-prolyl cis-trans isomerase slyD	16388577	SlyD proteins from different species exhibit high prolyl isomerase and chaperone activities.

O08538	ANGP1_MOUSE	Angiopoietin-1	8980223	Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning.

Q14103	HNRPD_HUMAN	Heterogeneous nuclear ribonucleoprotein D0	3754960	A cDNA clone of the hnRNP C proteins and its homology with the single-stranded DNA binding protein UP2.

Q9HFA4	XYNA_ASPOR	Endo-1,4-beta-xylanase A	11210150	Molecular cloning, overexpression, and purification of a major xylanase from Aspergillus oryzae.

O35973	PER1_MOUSE	Period circadian protein homolog 1	10231394	A mammalian ortholog of Drosophila timeless, highly expressed in SCN and retina, forms a complex with mPER1.

Q64428	ECHA_RAT	Trifunctional enzyme subunit alpha, mitochondrial	8253773	Molecular cloning of the cDNAs for the subunits of rat mitochondrial fatty acid beta-oxidation multienzyme complex. Structural and functional relationships to other mitochondrial and peroxisomal beta- oxidation enzymes.

O01382	ICE_DROME	Caspase	10675329	The Drosophila caspase DRONC is regulated by DIAP1.

Q9NIF3	UBQL_DICDI	Ubiquilin	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P53312	SUCB_YEAST	Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial	9874242	Genes of succinyl-CoA ligase from Saccharomyces cerevisiae.

Q13257	MD2L1_HUMAN	Mitotic spindle assembly checkpoint protein MAD2A	18981471	Tpr directly binds to Mad1 and Mad2 and is important for the Mad1- Mad2-mediated mitotic spindle checkpoint.

Q95YL5	PEFA_DICDI	Penta-EF hand domain-containing protein 1	11481037	Identification and characterization of two penta-EF-hand Ca(2+)- binding proteins in Dictyostelium discoideum.

Q9VPQ6	USH_DROME	Zinc finger protein ush	12374748	Two isoforms of Serpent containing either one or two GATA zinc fingers have different roles in Drosophila haematopoiesis.

Q9UKR5	ERG28_HUMAN	Probable ergosterol biosynthetic protein 28	10449901	A novel human gene, encoding a potential membrane protein conserved from yeast to man, is strongly expressed in testis and cancer cell lines.

Q8N9W6	BOLL_HUMAN	Protein boule-like	11390979	A gene family required for human germ cell development evolved from an ancient meiotic gene conserved in metazoans.

P40078	NSA2_YEAST	Ribosome biogenesis protein NSA2	16861225	Nsa2 is an unstable, conserved factor required for the maturation of 27 SB pre-rRNAs.

P01780	HV319_HUMAN	Ig heavy chain V-III region JON	4522793	Variable region sequences of five human immunoglobulin heavy chains of the VH3 subgroup: definitive identification of four heavy chain hypervariable regions.

P12755	SKI_HUMAN	Ski oncogene	19049980	SKI and MEL1 cooperate to inhibit transforming growth factor-beta signal in gastric cancer cells.

Q06063	DUS4_YEAST	tRNA-dihydrouridine synthase 4	14970222	The specificities of four yeast dihydrouridine synthases for cytoplasmic tRNAs.

P36616	DSK1_SCHPO	Protein kinase dsk1	9488736	Fission yeast mitotic regulator Dsk1 is an SR protein-specific kinase.

O35132	CP27B_RAT	25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	9333115	The 25-hydroxyvitamin D 1-alpha-hydroxylase gene maps to the pseudovitamin D-deficiency rickets (PDDR) disease locus.

Q0VF58	COJA1_MOUSE	Collagen alpha-1(XIX) chain	15302855	Esophageal muscle physiology and morphogenesis require assembly of a collagen XIX-rich basement membrane zone.

P53960	YNE0_YEAST	Putative alanyl-tRNA editing protein alaX	14663147	Trans-editing of mischarged tRNAs.

Q9P786	MTD1_SCHPO	Methylenetetrahydrofolate dehydrogenase [NAD+]	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q924X1	EPGN_MOUSE	Epigen	11278323	Cloning and biological activity of epigen, a novel member of the epidermal growth factor superfamily.

Q8VCN6	CD99_MOUSE	CD99 antigen	14970179	Activation of natural killer cells and dendritic cells upon recognition of a novel CD99-like ligand by paired immunoglobulin-like type 2 receptor.

Q91619	NODAL_XENLA	Nodal homolog	8582278	Nodal-related signals induce axial mesoderm and dorsalize mesoderm during gastrulation.

P54759	EPHA7_RAT	Ephrin type-A receptor 7	7731712	Identification of full-length and truncated forms of Ehk-3, a novel member of the Eph receptor tyrosine kinase family.

Q5XI59	RNF10_RAT	RING finger protein 10	18941509	A novel function of RING finger protein 10 in transcriptional regulation of the myelin-associated glycoprotein gene and myelin formation in Schwann cells.

Q5TAT6	CODA1_HUMAN	Collagen alpha-1(XIII) chain	10865988	Type XIII collagen is widely expressed in the adult and developing human eye and accentuated in the ciliary muscle, the optic nerve and the neural retina.

P75851	SSUC_ECOLI	Putative aliphatic sulfonates transport permease protein ssuC	10506196	The Escherichia coli ssuEADCB gene cluster is required for the utilization of sulfur from aliphatic sulfonates and is regulated by the transcriptional activator Cbl.

P82980	RET5_HUMAN	Retinol-binding protein 5	11274389	Identification, retinoid binding and X-ray analysis of a human retinol-binding protein.

Q80Z64	NANOG_MOUSE	Homeobox protein NANOG	12787504	The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells.

Q9M291	SC24C_ARATH	Protein transport protein Sec24-like CEF	11053466	CEF, a sec24 homologue of Arabidopsis thaliana, enhances the survival of yeast under oxidative stress conditions.

Q10113	MAL3_SCHPO	Microtubule integrity protein mal3	9348288	Mal3, the fission yeast homologue of the human APC-interacting protein EB-1 is required for microtubule integrity and the maintenance of cell form.

Q96PD5	PGRP2_HUMAN	N-acetylmuramoyl-L-alanine amidase	7663175	Characterization of human serum N-acetylmuramyl-L-alanine amidase purified by affinity chromatography.

P97369	NCF4_MOUSE	Neutrophil cytosol factor 4	9490028	Functional modules and expression of mouse p40(phox) and p67(phox), SH3-domain-containing proteins involved in the phagocyte NADPH oxidase complex.

P81299	CDC14_CAEEL	Probable tyrosine-protein phosphatase cdc-14	15247923	The CDC-14 phosphatase controls developmental cell-cycle arrest in C. elegans.

P16664	RGP1_YEAST	Reduced growth phenotype protein 1	10990452	Ric1p and Rgp1p form a complex that catalyses nucleotide exchange on Ypt6p.

Q9Z2R9	E2AK1_MOUSE	Eukaryotic translation initiation factor 2-alpha kinase 1	11726526	Heme-regulated eIF2alpha kinase (HRI) is required for translational regulation and survival of erythroid precursors in iron deficiency.

P16092	FGFR1_MOUSE	Basic fibroblast growth factor receptor 1	2161540	A murine fibroblast growth factor (FGF) receptor expressed in CHO cells is activated by basic FGF and Kaposi FGF.

A4ZNR5	NKD2L_DANRE	Protein naked cuticle homolog 2-like	17689523	Zebrafish Naked1 and Naked2 antagonize both canonical and non- canonical Wnt signaling.

Q90267	OTX1A_DANRE	Homeobox protein OTX1 A	16611693	Differentiation of cerebellar cell identities in absence of Fgf signalling in zebrafish Otx morphants.

Q9UT79	MSC1_SCHPO	Multicopy suppressor of chk1 protein 1	15082762	A novel protein with similarities to Rb binding protein 2 compensates for loss of Chk1 function and affects histone modification in fission yeast.

Q12789	TF3C1_HUMAN	General transcription factor 3C polypeptide 1	19299493	Biochemical and genetic evidence for a role of IGHMBP2 in the translational machinery.

Q9NQS7	INCE_HUMAN	Inner centromere protein	14610074	Aurora-B phosphorylation in vitro identifies a residue of survivin that is essential for its localization and binding to inner centromere protein (INCENP) in vivo.

P36872	2ABA_DROME	Protein phosphatase PP2A 55 kDa regulatory subunit	8382567	The 55 kd regulatory subunit of Drosophila protein phosphatase 2A is required for anaphase.

P38212	RCR1_YEAST	Protein RCR1	15590673	A novel endoplasmic reticulum membrane protein Rcr1 regulates chitin deposition in the cell wall of Saccharomyces cerevisiae.

Q0VIL3	OTOMP_DANRE	Otolith matrix protein 1	15905077	Otolith matrix proteins OMP-1 and Otolin-1 are necessary for normal otolith growth and their correct anchoring onto the sensory maculae.

Q9JLL3	TNR19_MOUSE	Tumor necrosis factor receptor superfamily member 19	10764796	TROY, a newly identified member of the tumor necrosis factor receptor superfamily, exhibits a homology with Edar and is expressed in embryonic skin and hair follicles.

P05538	DQB2_HUMAN	HLA class II histocompatibility antigen, DQ beta 2 chain	2564844	Remarkable sequence conservation of the HLA-DQB2 locus (DX beta) within the highly polymorphic DQ subregion of the human MHC.

Q75Q40	TOM40_RAT	Mitochondrial import receptor subunit TOM40 homolog	15347672	Membrane-embedded C-terminal segment of rat mitochondrial TOM40 constitutes protein-conducting pore with enriched beta-structure.

O94751	BUB1_SCHPO	Checkpoint serine/threonine-protein kinase bub1	15509783	Kinetochore targeting of fission yeast Mad and Bub proteins is essential for spindle checkpoint function but not for all chromosome segregation roles of Bub1p.

Q20646	CEP1_CAEEL	Transcription factor cep-1	17581633	Structural evolution of C-terminal domains in the p53 family.

O60113	YG64_SCHPO	Uncharacterized amino-acid permease C15C4.04c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P69423	TATC_ECOLI	Sec-independent protein translocase protein tatC	11279240	TatB and TatC form a functional and structural unit of the twin- arginine translocase from Escherichia coli.

Q62671	UBR5_RAT	E3 ubiquitin-protein ligase UBR5	12239083	Characterization of rat100, a 300-kilodalton ubiquitin-protein ligase induced in germ cells of the rat testis and similar to the Drosophila hyperplastic discs gene.

P08621	RU17_HUMAN	U1 small nuclear ribonucleoprotein 70 kDa	9447963	Sip1, a novel RS domain-containing protein essential for pre-mRNA splicing.

O94979	SC31A_HUMAN	Protein transport protein Sec31A	16957052	The Ca2+-binding protein ALG-2 is recruited to endoplasmic reticulum exit sites by Sec31A and stabilizes the localization of Sec31A.

P52198	RND2_HUMAN	Rho-related GTP-binding protein RhoN	12590651	Rho family GTPase Rnd2 interacts and co-localizes with MgcRacGAP in male germ cells.

P00573	RPOL_BPT7	DNA-directed RNA polymerase	9670025	Structure of T7 RNA polymerase complexed to the transcriptional inhibitor T7 lysozyme.

O73682	VGFAA_DANRE	Vascular endothelial growth factor A-A	17698971	Duplicate VegfA genes and orthologues of the KDR receptor tyrosine kinase family mediate vascular development in the zebrafish.

Q6NZ67	MZT2B_HUMAN	Mitotic-spindle organizing protein 2B	20360068	Systematic analysis of human protein complexes identifies chromosome segregation proteins.

P39904	VPS52_YEAST	Vacuolar protein sorting-associated protein 52	10637310	Vps52p, Vps53p, and Vps54p form a novel multisubunit complex required for protein sorting at the yeast late Golgi.

Q9UGU0	TCF20_HUMAN	Transcription factor 20	10995766	The nuclear factor SPBP contains different functional domains and stimulates the activity of various transcriptional activators.

P49893	WN11B_XENLA	Protein Wnt-11b	15857909	Essential role of non-canonical Wnt signalling in neural crest migration.

P22147	XRN1_YEAST	5'-3' exoribonuclease 1	12730603	Decapping and decay of messenger RNA occur in cytoplasmic processing bodies.

O75122	CLAP2_HUMAN	CLIP-associating protein 2	11290329	Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts.

Q9JIL6	GPC5D_MOUSE	G-protein coupled receptor family C group 5 member D	11311935	Cloning and characterization of a human orphan family C G-protein coupled receptor GPRC5D.

Q05062	CDC42_CAEEL	Cell division control protein 42 homolog	8824291	The Caenorhabditis elegans p21-activated kinase (CePAK) colocalizes with CeRac1 and CDC42Ce at hypodermal cell boundaries during embryo elongation.

P25870	CLH_DICDI	Clathrin heavy chain	9238018	A novel role for clathrin in cytokinesis.

P48598	IF4E_DROME	Eukaryotic translation initiation factor 4E	8663200	Alternatively spliced transcripts from the Drosophila eIF4E gene produce two different Cap-binding proteins.

Q9BWQ8	FAIM2_HUMAN	Fas apoptotic inhibitory molecule 2	10535980	LFG: an anti-apoptotic gene that provides protection from fas- mediated cell death.

P11496	CORZ_PERAM	Corazonin	2753132	Isolation and structure of corazonin, a cardioactive peptide from the American cockroach.

Q8CIG3	KDM1B_MOUSE	Lysine-specific histone demethylase 1B	19407342	A novel mammalian flavin-dependent histone demethylase.

Q9BUK6	MSTO1_HUMAN	Protein misato homolog 1	17349998	Human Misato regulates mitochondrial distribution and morphology.

Q39238	TSL_ARATH	Serine/threonine-protein kinase TOUSLED	9038200	TOUSLED is a nuclear serine/threonine protein kinase that requires a coiled-coil region for oligomerization and catalytic activity.

Q9LL45	TBP1_ORYSJ	Telomere-binding protein 1	17586654	Suppression of RICE TELOMERE BINDING PROTEIN 1 results in severe and gradual developmental defects accompanied by genome instability in rice.

Q9SYX2	SPA1_ARATH	Protein SUPPRESSOR OF PHYA-105 1	16709190	The Arabidopsis SPA1 gene is required for circadian clock function and photoperiodic flowering.

Q12124	MED2_YEAST	Mediator of RNA polymerase II transcription subunit 2	9420330	The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain.

P49847	TAF6_DROME	Transcription initiation factor TFIID subunit 6	8598927	Structural similarity between TAFs and the heterotetrameric core of the histone octamer.

P62167	NCS1_CHICK	Neuronal calcium sensor 1	8903951	Identification of neuronal calcium sensor (NCS-1) possibly involved in the regulation of receptor phosphorylation.

P00759	KLK2_RAT	Tonin	2550051	Characterization of genes encoding rat tonin and a kallikrein-like serine protease.

O22456	SEP3_ARATH	Developmental protein SEPALLATA 3	10821278	B and C floral organ identity functions require SEPALLATA MADS-box genes.

Q9WTV7	RNF12_MOUSE	E3 ubiquitin-protein ligase RLIM	19945382	RNF12 is an X-encoded dose-dependent activator of X chromosome inactivation.

D4GUF6	SAMP1_HALVD	Small archaeal modifier protein 1	20054389	Ubiquitin-like small archaeal modifier proteins (SAMPs) in Haloferax volcanii.

P04176	PH4H_RAT	Phenylalanine-4-hydroxylase	10331871	Structural basis of autoregulation of phenylalanine hydroxylase.

Q13491	GPM6B_HUMAN	Neuronal membrane glycoprotein M6-b	8661015	Chromosomal mapping of the human M6 genes.

Q62662	FRK_RAT	Tyrosine-protein kinase FRK	8760296	The apical membranes of maturing gut columnar epithelial cells contain the enzymatically active form of a newly identified fyn- related tyrosine kinase.

Q03081	MET31_YEAST	Transcriptional regulator MET31	9799240	Multiple transcriptional activation complexes tether the yeast activator Met4 to DNA.

Q8N5P1	ZC3H8_HUMAN	Zinc finger CCCH domain-containing protein 8	12077251	Transcriptional regulation of GATA-3 by an intronic regulatory region and fetal liver zinc finger protein 1.

P33441	MFT1_YEAST	THO complex subunit MFT1	11979277	TREX is a conserved complex coupling transcription with messenger RNA export.

P40202	CCS1_YEAST	Superoxide dismutase 1 copper chaperone	11500508	A fraction of yeast Cu,Zn-superoxide dismutase and its metallochaperone, CCS, localize to the intermembrane space of mitochondria. A physiological role for SOD1 in guarding against mitochondrial oxidative damage.

Q39099	XTH4_ARATH	Xyloglucan endotransglucosylase/hydrolase protein 4	10557219	Expression of endoxyloglucan transferase genes in acaulis mutants of Arabidopsis.

O01971	EMR1_CAEEL	Emerin homolog 1	12490171	Transmission electron microscope studies of the nuclear envelope in Caenorhabditis elegans embryos.

Q7K4M4	TEF_DROME	Protein teflon	11139508	The teflon gene is required for maintenance of autosomal homolog pairing at meiosis I in male Drosophila melanogaster.

O97148	MTH_DROME	G-protein coupled receptor Mth	9794765	Extended life-span and stress resistance in the Drosophila mutant methuselah.

O59868	ATC1_SCHPO	Calcium-transporting ATPase 1	14723709	Pmr1, a P-type ATPase, and Pdt1, an Nramp homologue, cooperatively regulate cell morphogenesis in fission yeast: the importance of Mn2+ homeostasis.

Q6VUP9	AP2E_MOUSE	Transcription factor AP-2-epsilon	14572467	Cloning and characterization of the mouse AP-2 epsilon gene: a novel family member expressed in the developing olfactory bulb.

Q9C6Z2	NUD25_ARATH	Nudix hydrolase 25	18345354	A diadenosine 5',5''-P1P4 tetraphosphate (Ap4A) hydrolase from Arabidopsis thaliana that is activated preferentially by Mn2+ ions.

P15814	IGLL1_HUMAN	Immunoglobulin lambda-like polypeptide 1	2501791	Immunoglobulin lambda light-chain-related genes 14.1 and 16.1 are expressed in pre-B cells and may encode the human immunoglobulin omega light-chain protein.

P51610	HCFC1_HUMAN	Host cell factor 1	7876203	The cellular C1 factor of the herpes simplex virus enhancer complex is a family of polypeptides.

P20424	SRP54_YEAST	Signal recognition particle subunit SRP54	7925282	Subunits of the Saccharomyces cerevisiae signal recognition particle required for its functional expression.

P97820	M4K4_MOUSE	Mitogen-activated protein kinase kinase kinase kinase 4	9135144	NIK is a new Ste20-related kinase that binds NCK and MEKK1 and activates the SAPK/JNK cascade via a conserved regulatory domain.

P83293	GR64A_DROME	Putative gustatory receptor 64a	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

Q8IMA8	PANG2_DROME	Protein pangolin, isoform J	9118222	Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF.

Q9Y0H4	SUDX_DROME	E3 ubiquitin-protein ligase Su(dx)	12648496	Down-regulation of Notch target gene expression by Suppressor of deltex.

Q9JIC3	DCR1A_MOUSE	DNA cross-link repair 1A protein	10848582	Disruption of mouse SNM1 causes increased sensitivity to the DNA interstrand cross-linking agent mitomycin C.

P40208	GID8_YEAST	Glucose-induced degradation protein 8	12686616	Catabolite degradation of fructose-1,6-bisphosphatase in the yeast Saccharomyces cerevisiae: a genome-wide screen identifies eight novel GID genes and indicates the existence of two degradation pathways.

Q9VQG2	APH1_DROME	Gamma-secretase subunit Aph-1	12110170	aph-1 and pen-2 are required for Notch pathway signaling, gamma- secretase cleavage of betaAPP, and presenilin protein accumulation.

P20965	PABPA_XENLA	Polyadenylate-binding protein 1-A	10996799	Interaction of eIF4G with poly(A)-binding protein stimulates translation and is critical for Xenopus oocyte maturation.

O14979	HNRDL_HUMAN	Heterogeneous nuclear ribonucleoprotein D-like	9538234	Cloning and characterization of a cDNA encoding a novel heterogeneous nuclear ribonucleoprotein-like protein and its expression in myeloid leukemia cells.

P32600	TOR2_YEAST	Serine/threonine-protein kinase TOR2	12408816	Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control.

Q05931	HSP7Q_YEAST	Heat shock protein SSQ1, mitochondrial	9660806	Mt-Hsp70 homolog, Ssc2p, required for maturation of yeast frataxin and mitochondrial iron homeostasis.

P47123	MOG1_YEAST	Nuclear import protein MOG1	11509570	Interaction between Ran and Mog1 is required for efficient nuclear protein import.

Q6A037	N4BP1_MOUSE	NEDD4-binding protein 1	20233849	N4BP1 is a newly identified nucleolar protein that undergoes SUMO- regulated polyubiquitylation and proteasomal turnover at promyelocytic leukemia nuclear bodies.

Q9YGK8	IRX1A_XENLA	Iroquois-class homeodomain protein irx-1-A	11171338	The Wnt-activated Xiro1 gene encodes a repressor that is essential for neural development and downregulates Bmp4.

P40380	RUM1_SCHPO	Cyclin-dependent kinase inhibitor rum1	14653990	Regulated mRNA stability of the Cdk inhibitor Rum1 links nutrient status to cell cycle progression.

P39730	IF2P_YEAST	Eukaryotic translation initiation factor 5B	9624054	Promotion of met-tRNAiMet binding to ribosomes by yIF2, a bacterial IF2 homolog in yeast.

Q9LK64	AB3C_ARATH	ABC transporter C family member 3	9681016	An ABC-transporter of Arabidopsis thaliana has both glutathione- conjugate and chlorophyll catabolite transport activity.

Q10719	FUS1_SCHPO	Cell fusion protein fus1	7791776	Characterization of fus1 of Schizosaccharomyces pombe: a developmentally controlled function needed for conjugation.

Q8IUX7	AEBP1_HUMAN	Adipocyte enhancer-binding protein 1	8920928	A cDNA cloning of human AEBP1 from primary cultured osteoblasts and its expression in a differentiating osteoblastic cell line.

Q8TF05	PP4R1_HUMAN	Serine/threonine-protein phosphatase 4 regulatory subunit 1	10026142	Purification and identification of a novel subunit of protein serine/threonine phosphatase 4.

O35664	INAR2_MOUSE	Interferon alpha/beta receptor 2	9322767	Mammalian type I interferon receptors consists of two subunits: IFNaR1 and IFNaR2.

Q99N80	SYTL1_MOUSE	Synaptotagmin-like protein 1	18266782	Slp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapse.

Q96SZ6	CK5P1_HUMAN	CDK5 regulatory subunit-associated protein 1	10721722	Cloning of three novel neuronal Cdk5 activator binding proteins.

Q5SXM2	SNPC4_HUMAN	snRNA-activating protein complex subunit 4	11056176	A map of protein-protein contacts within the small nuclear RNA- activating protein complex SNAPc.

P98179	RBM3_HUMAN	Putative RNA-binding protein 3	8634703	RBM3, a novel human gene in Xp11.23 with a putative RNA-binding domain.

Q9VFG8	KIBRA_DROME	Protein kibra	20159600	The WW domain protein Kibra acts upstream of Hippo in Drosophila.

P14408	FUMH_RAT	Fumarate hydratase, mitochondrial	2914923	Rat liver mitochondrial and cytosolic fumarases with identical amino acid sequences are encoded from a single gene.

Q8K1B8	URP2_MOUSE	Fermitin family homolog 3	18278053	Kindlin-3 is essential for integrin activation and platelet aggregation.

Q8TEL6	TP4AP_HUMAN	Short transient receptor potential channel 4-associated protein	20551172	Myc protein is stabilized by suppression of a novel E3 ligase complex in cancer cells.

P52435	RPB11_HUMAN	DNA-directed RNA polymerase II subunit RPB11-a	9852112	Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.

P84824	BRK11_ASCTR	Bradykinin-like peptide RD-11	15922344	Bradykinin-related peptides and tryptophyllins in the skin secretions of the most primitive extant frog, Ascaphus truei.

Q18007	ACM1_CAEEL	Probable muscarinic acetylcholine receptor gar-1	9886054	Cloning and expression of a G protein-linked acetylcholine receptor from Caenorhabditis elegans.

P51582	P2RY4_HUMAN	P2Y purinoceptor 4	8537335	Cloning, expression, and chromosomal localization of the human uridine nucleotide receptor gene.

Q9UT83	MUG28_SCHPO	Meiotically up-regulated gene 28 protein	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

Q38876	AGL8_ARATH	Agamous-like MADS-box protein AGL8	9502732	The FRUITFULL MADS-box gene mediates cell differentiation during Arabidopsis fruit development.

Q9TEM3	PRPC_EMENI	2-methylcitrate synthase, mitochondrial	10712680	Methylcitrate synthase from Aspergillus nidulans: implications for propionate as an antifungal agent.

P20626	PLD_CORPS	Phospholipase D	7934899	Targeted mutagenesis of the phospholipase D gene results in decreased virulence of Corynebacterium pseudotuberculosis.

Q03677	MTND_YEAST	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase	14562095	Global analysis of protein localization in budding yeast.

Q94F08	HIPL2_ARATH	HIPL2 protein	12805588	Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis.

Q8INZ2	GR36C_DROME	Putative gustatory receptor 36c	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

P43558	OTU1_YEAST	Ubiquitin thioesterase OTU1	16427015	Functional division of substrate processing cofactors of the ubiquitin-selective Cdc48 chaperone.

Q8IV61	GRP3_HUMAN	Ras guanyl-releasing protein 3	10934204	Identification of guanine nucleotide exchange factors (GEFs) for the Rap1 GTPase. Regulation of MR-GEF by M-Ras-GTP interaction.

P75830	MACA_ECOLI	Macrolide-specific efflux protein macA	11544226	Novel macrolide-specific ABC-type efflux transporter in Escherichia coli.

Q5ABG1	SET1_CANAL	Histone-lysine N-methyltransferase, H3 lysine-4 specific	16629671	Candida albicans SET1 encodes a histone 3 lysine 4 methyltransferase that contributes to the pathogenesis of invasive candidiasis.

Q62083	PICK1_MOUSE	PRKCA-binding protein	7844141	PICK1: a perinuclear binding protein and substrate for protein kinase C isolated by the yeast two-hybrid system.

Q09PK2	APRV1_MOUSE	Retroviral-like aspartic protease 1	16837463	Mouse homologue of skin-specific retroviral-like aspartic protease involved in wrinkle formation.

P52655	TF2AA_HUMAN	Transcription initiation factor IIA subunit 1	8224848	A single cDNA, hTFIIA/alpha, encodes both the p35 and p19 subunits of human TFIIA.

P26441	CNTF_HUMAN	Ciliary neurotrophic factor	1840538	Sequence and structural organization of the human gene encoding ciliary neurotrophic factor.

P42283	LOLA1_DROME	Longitudinals lacking protein, isoform G	8050351	Lola encodes a putative transcription factor required for axon growth and guidance in Drosophila.

P57095	AXN2_DANRE	Axin-2	10704853	Cooperative roles of Bozozok/Dharma and Nodal-related proteins in the formation of the dorsal organizer in zebrafish.

Q96PD5	PGRP2_HUMAN	N-acetylmuramoyl-L-alanine amidase	11461926	Peptidoglycan recognition proteins: a novel family of four human innate immunity pattern recognition molecules.

P01703	LV105_HUMAN	Ig lambda chain V-I region NEWM	4814727	Amino acid sequence of the (lambda) light chain of a human myeloma immunoglobulin (IgG New).

P26817	ARBK1_RAT	Beta-adrenergic receptor kinase 1	1403099	The G-protein-coupled receptor kinases beta ARK1 and beta ARK2 are widely distributed at synapses in rat brain.

Q9UIG0	BAZ1B_HUMAN	Tyrosine-protein kinase BAZ1B	19092802	WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity.

Q50755	HDRB_METTM	CoB--CoM heterodisulfide reductase subunit B	7925445	The heterodisulfide reductase from Methanobacterium thermoautotrophicum contains sequence motifs characteristic of pyridine-nucleotide-dependent thioredoxin reductases.

Q5SUQ9	CTC1_MOUSE	CST complex subunit CTC1	19119139	A DNA polymerase-{alpha}primase cofactor with homology to replication protein A-32 regulates DNA replication in mammalian cells.

P0A9W0	ULAR_ECOLI	HTH-type transcriptional regulator ulaR	12374842	The gene yjfQ encodes the repressor of the yjfR-X regulon (ula), which is involved in L-ascorbate metabolism in Escherichia coli.

Q9C525	BGL21_ARATH	Beta-glucosidase 21	9177312	A phosphate-starvation inducible beta-glucosidase gene (psr3.2) isolated from Arabidopsis thaliana is a member of a distinct subfamily of the BGA family.

P53260	GATF_YEAST	Glutamyl-tRNA(Gln) amidotransferase subunit F, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

P47069	MPS3_YEAST	Spindle pole body assembly component MPS3	18039933	Telomere anchoring at the nuclear periphery requires the budding yeast Sad1-UNC-84 domain protein Mps3.

P40072	SLX8_YEAST	E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX8	16387868	Genetic analysis connects SLX5 and SLX8 to the SUMO pathway in Saccharomyces cerevisiae.

Q05609	CTR1_ARATH	Serine/threonine-protein kinase CTR1	8431946	CTR1, a negative regulator of the ethylene response pathway in Arabidopsis, encodes a member of the raf family of protein kinases.

P0CF95	BICR1_DANRE	Bicaudal D-related protein 1	20360680	Pericentrosomal targeting of Rab6 secretory vesicles by Bicaudal-D- related protein 1 (BICDR-1) regulates neuritogenesis.

Q11201	SIA4A_HUMAN	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1	10504389	Molecular cloning and expression of Galbeta1,3GalNAc alpha2, 3- sialyltransferase from human fetal liver.

O74740	CFT2_SCHPO	Cleavage factor two protein 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P18117	THBA_XENLA	Thyroid hormone receptor beta-A	12553426	The effects of endocrine-disrupting chemicals on thyroid hormone binding to Xenopus laevis transthyretin and thyroid hormone receptor.

P49435	APT1_YEAST	Adenine phosphoribosyltransferase 1	9357956	Purification and characterization of adenine phosphoribosyltransferase from Saccharomyces cerevisiae.

O00212	RHOD_HUMAN	Rho-related GTP-binding protein RhoD	9116026	Isolation of a novel human cDNA (rhoHP1) homologous to rho genes.

Q9UK73	FEM1B_HUMAN	Protein fem-1 homolog B	15601820	VHL-box and SOCS-box domains determine binding specificity for Cul2- Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.

O94813	SLIT2_HUMAN	Slit homolog 2 protein	17848514	Structural insights into the Slit-Robo complex.

Q9PVZ4	INSR_XENLA	Insulin receptor	7595277	Insulin receptors in Xenopus laevis liver and forelimb regenerates and the effects of local insulin deprivation on regeneration.

O35920	CAN9_RAT	Calpain-9	9524069	Molecular cloning and characterization of a novel tissue-specific calpain predominantly expressed in the digestive tract.

Q9UIG0	BAZ1B_HUMAN	Tyrosine-protein kinase BAZ1B	12837248	The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome.

Q14694	UBP10_HUMAN	Ubiquitin carboxyl-terminal hydrolase 10	19398555	The deubiquitinating enzyme USP10 regulates the post-endocytic sorting of cystic fibrosis transmembrane conductance regulator in airway epithelial cells.

P34240	ZRT3_YEAST	Zinc-regulated transporter 3	10856230	Zinc transporters that regulate vacuolar zinc storage in Saccharomyces cerevisiae.

Q91905	FXI1B_XENLA	Forkhead box protein I1-B	16079156	An essential role of Xenopus Foxi1a for ventral specification of the cephalic ectoderm during gastrulation.

Q16665	HIF1A_HUMAN	Hypoxia-inducible factor 1-alpha	9079689	Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway.

O89106	FHIT_MOUSE	Bis(5'-adenosyl)-triphosphatase	9699672	The murine Fhit locus: isolation, characterization, and expression in normal and tumor cells.

Q64654	CP51A_RAT	Lanosterol 14-alpha demethylase	7665087	Cloning and functional expression of the cDNA encoding rat lanosterol 14-alpha demethylase.

P28476	GBRR2_HUMAN	Gamma-aminobutyric acid receptor subunit rho-2	1315307	Identification of a putative gamma-aminobutyric acid (GABA) receptor subunit rho2 cDNA and colocalization of the genes encoding rho2 (GABRR2) and rho1 (GABRR1) to human chromosome 6q14-q21 and mouse chromosome 4.

P38116	ARL1_YEAST	ADP-ribosylation factor-like protein 1	9388248	Characterization of an ADP-ribosylation factor-like 1 protein in Saccharomyces cerevisiae.

Q8TAE7	KCNG3_HUMAN	Potassium voltage-gated channel subfamily G member 3	12060745	Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome.

Q70PP2	SMG1_DROME	Serine/threonine-protein kinase Smg1	16199763	Nonsense-mediated mRNA decay factors act in concert to regulate common mRNA targets.

Q9NYW3	TA2R7_HUMAN	Taste receptor type 2 member 7	10761934	A novel family of mammalian taste receptors.

O54926	SIVA_MOUSE	Apoptosis regulatory protein Siva	12478477	GITR interacts with the pro-apoptotic protein Siva and induces apoptosis.

P32379	PSA5_YEAST	Proteasome component PUP2	9087403	Structure of 20S proteasome from yeast at 2.4-A resolution.

O43003	MMF1_SCHPO	Protein mmf1, mitochondrial	12185840	Schizosaccharomyces pombe Pmf1p is structurally and functionally related to Mmf1p of Saccharomyces cerevisiae.

Q9LRM7	NCED6_ARATH	9-cis-epoxycarotenoid dioxygenase NCED6, chloroplastic	11532178	Regulation of drought tolerance by gene manipulation of 9-cis- epoxycarotenoid dioxygenase, a key enzyme in abscisic acid biosynthesis in Arabidopsis.

Q16563	SYPL1_HUMAN	Synaptophysin-like protein 1	1730063	Molecular cloning of a cDNA encoding a novel protein related to the neuronal vesicle protein synaptophysin.

P02730	B3AT_HUMAN	Band 3 anion transport protein	14734552	A novel missense mutation in AE1 causing autosomal dominant distal renal tubular acidosis retains normal transport function but is mistargeted in polarized epithelial cells.

Q12931	TRAP1_HUMAN	Heat shock protein 75 kDa, mitochondrial	7876093	Identification of a protein with homology to hsp90 that binds the type 1 tumor necrosis factor receptor.

Q8WU39	PERP1_HUMAN	Plasma cell-induced resident endoplasmic reticulum protein	11350957	Characterization of a novel proapoptotic caspase-2- and caspase-9- binding protein.

O42944	YBP9_SCHPO	Uncharacterized mannosyltransferase C16H5.09c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P53973	HDA1_YEAST	Histone deacetylase HDA1	8962081	HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription.

Q09969	BNIP3_CAEEL	NIP3 homolog	17934462	DAF-16/FOXO targets genes that regulate tumor growth in Caenorhabditis elegans.

O14146	YEWA_SCHPO	Uncharacterized protein C3G6.10c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O94512	OBP1_SCHPO	Oxysterol-binding protein-like protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9S702	AK3_ARATH	Aspartokinase 3, chloroplastic	11569502	Identification of a monofunctional aspartate kinase gene of Arabidopsis thaliana with spatially and temporally regulated expression.

P05230	FGF1_HUMAN	Heparin-binding growth factor 1	3778488	Amino acid sequence of human acidic fibroblast growth factor.

Q28488	CRYM_MACFL	Mu-crystallin	1384048	Mu-crystallin is a mammalian homologue of Agrobacterium ornithine cyclodeaminase and is expressed in human retina.

Q3ECS3	BGL35_ARATH	Myrosinase 5	19703694	Myrosinases from root and leaves of Arabidopsis thaliana have different catalytic properties.

Q10103	CHP1_SCHPO	Chromo domain-containing protein 1	14704433	RNAi-mediated targeting of heterochromatin by the RITS complex.

Q5FVL0	VA0D2_RAT	V-type proton ATPase subunit d 2	16192400	Distinct expression patterns of different subunit isoforms of the V- ATPase in the rat epididymis.

P59826	LPLC3_HUMAN	Long palate, lung and nasal epithelium carcinoma-associated protein 3	12837268	Expansion of the BPI family by duplication on human chromosome 20: characterization of the RY gene cluster in 20q11.21 encoding olfactory transporters/antimicrobial-like peptides.

O60563	CCNT1_HUMAN	Cyclin-T1	9499409	Identification of multiple cyclin subunits of human P-TEFb.

Q9BRR0	ZKSC3_HUMAN	Zinc finger protein with KRAB and SCAN domains 3	18940803	Unbiased screening for transcriptional targets of ZKSCAN3 identifies integrin beta 4 and vascular endothelial growth factor as downstream targets.

Q91904	FXI1A_XENLA	Forkhead box protein I1-A	16079156	An essential role of Xenopus Foxi1a for ventral specification of the cephalic ectoderm during gastrulation.

Q7LDG7	GRP2_HUMAN	RAS guanyl-releasing protein 2	9789079	A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia.

P51667	MLRV_MOUSE	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform	1379240	Myosin light chain-2 luciferase transgenic mice reveal distinct regulatory programs for cardiac and skeletal muscle-specific expression of a single contractile protein gene.

Q27297	RAD51_DROME	DNA repair protein Rad51 homolog	9362456	Oocyte determination and the origin of polarity in Drosophila: the role of the spindle genes.

O74428	YQ5C_SCHPO	Uncharacterized protein C162.12	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8VIG6	TRAIP_MOUSE	TRAF-interacting protein	9104814	TRAF-interacting protein (TRIP): a novel component of the tumor necrosis factor receptor (TNFR)- and CD30-TRAF signaling complexes that inhibits TRAF2-mediated NF-kappaB activation.

P20338	RAB4A_HUMAN	Ras-related protein Rab-4A	2501306	The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion.

Q92797	SYMPK_HUMAN	Symplekin	18688255	Conserved motifs in both CPSF73 and CPSF100 are required to assemble the active endonuclease for histone mRNA 3'-end maturation.

P39769	PHP_DROME	Polyhomeotic-proximal chromatin protein	9343432	A domain shared by the polycomb group proteins Scm and ph mediates heterotypic and homotypic interactions.

O14862	AIM2_HUMAN	Interferon-inducible protein AIM2	9242382	Cloning a novel member of the human interferon-inducible gene family associated with control of tumorigenicity in a model of human melanoma.

Q712U5	ARP19_RAT	cAMP-regulated phosphoprotein 19	12221279	Nerve growth factor controls GAP-43 mRNA stability via the phosphoprotein ARPP-19.

P84022	SMAD3_HUMAN	Mothers against decapentaplegic homolog 3	19049980	SKI and MEL1 cooperate to inhibit transforming growth factor-beta signal in gastric cancer cells.

Q9FF66	UBC22_ARATH	Ubiquitin-conjugating enzyme E2 22	16339806	Genome analysis and functional characterization of the E2 and RING- type E3 ligase ubiquitination enzymes of Arabidopsis.

Q99176	SRN2_YEAST	Protein SRN2	16615894	Structural and functional organization of the ESCRT-I trafficking complex.

Q10447	PPK2_SCHPO	Protein kinase domain-containing protein ppk2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q13651	I10R1_HUMAN	Interleukin-10 receptor subunit alpha	8120391	Expression cloning and characterization of a human IL-10 receptor.

Q16270	IBP7_HUMAN	Insulin-like growth factor-binding protein 7	8939990	Synthesis and characterization of insulin-like growth factor-binding protein (IGFBP)-7. Recombinant human mac25 protein specifically binds IGF-I and -II.

P36051	MCD4_YEAST	GPI ethanolamine phosphate transferase 1	12023081	Correct GPI-anchor synthesis is required for the incorporation of endoglucanase/glucanosyltransferase Bgl2p into the Saccharomyces cerevisiae cell wall.

P49005	DPOD2_HUMAN	DNA polymerase delta subunit 2	15670210	Human Werner helicase interacting protein 1 (WRNIP1) functions as a novel modulator for DNA polymerase delta.

Q9Z132	RSPO1_MOUSE	R-spondin-1	16543246	Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression.

O93852	ALO_CANAL	D-arabinono-1,4-lactone oxidase	11349062	Deficiency of D-erythroascorbic acid attenuates hyphal growth and virulence of Candida albicans.

P30776	RAD21_SCHPO	Cohesin subunit rad21	11069892	Characterization of fission yeast cohesin: essential anaphase proteolysis of Rad21 phosphorylated in the S phase.

P14599	A4_DROME	Beta-amyloid-like protein	16628230	Drosophila homolog of APP-BP1 (dAPP-BP1) interacts antagonistically with APPL during Drosophila development.

O44518	CYFIP_CAEEL	Cytoplasmic FMR1-interacting protein homolog	11877381	The GEX-2 and GEX-3 proteins are required for tissue morphogenesis and cell migrations in C. elegans.

Q9P7G0	YKY4_SCHPO	Uncharacterized NOC2 family protein C1142.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9XFD1	NCBP2_ARATH	Nuclear cap-binding protein subunit 2	12427994	Localization, ion channel regulation, and genetic interactions during abscisic acid signaling of the nuclear mRNA cap-binding protein, ABH1.

Q9C0B1	FTO_HUMAN	Alpha-ketoglutarate-dependent dioxygenase FTO	18775698	Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO.

Q9Y3C0	CCD53_HUMAN	WASH complex subunit CCDC53	19922875	The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex.

Q13077	TRAF1_HUMAN	TNF receptor-associated factor 1	10809768	TAJ, a novel member of the tumor necrosis factor receptor family, activates the c-Jun N-terminal kinase pathway and mediates caspase- independent cell death.

Q20106	HRG4_CAEEL	Heme transporter hrg-4	18418376	Haem homeostasis is regulated by the conserved and concerted functions of HRG-1 proteins.

Q9Y2P7	ZN256_HUMAN	Zinc finger protein 256	18060868	A novel GDNF-inducible gene, BMZF3, encodes a transcriptional repressor associated with KAP-1.

P48380	RFX3_HUMAN	Transcription factor RFX3	20148032	Rfx6 directs islet formation and insulin production in mice and humans.

Q9LND7	SKI16_ARATH	F-box protein SKIP16	12795696	Protein interaction analysis of SCF ubiquitin E3 ligase subunits from Arabidopsis.

Q9LU10	DEGP8_ARATH	Protease Do-like 8, chloroplastic	11719511	Proteome map of the chloroplast lumen of Arabidopsis thaliana.

O15232	MATN3_HUMAN	Matrilin-3	9350998	Matrilin-3 from chicken cartilage.

Q62418	DBNL_MOUSE	Drebrin-like protein	9630982	Cloning of ligand targets: systematic isolation of SH3 domain- containing proteins.

Q08224	THI20_YEAST	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20	10383756	Genetic redundancy and gene fusion in the genome of the Baker's yeast Saccharomyces cerevisiae: functional characterization of a three- member gene family involved in the thiamine biosynthetic pathway.

P40047	ALDH5_YEAST	Aldehyde dehydrogenase 5, mitochondrial	15256563	Functional analysis of the ALD gene family of Saccharomyces cerevisiae during anaerobic growth on glucose: the NADP+-dependent Ald6p and Ald5p isoforms play a major role in acetate formation.

O77086	C3G_DROME	Guanine nucleotide-releasing factor 2	9878058	Activation of the Drosophila C3G leads to cell fate changes and overproliferation during development, mediated by the RAS-MAPK pathway and RAP1.

Q9NS56	TOPRS_HUMAN	E3 ubiquitin-protein ligase Topors	10415337	Identification of a novel gene encoding a p53-associated protein.

Q07914	TIM14_YEAST	Mitochondrial import inner membrane translocase subunit TIM14	14605210	J protein cochaperone of the mitochondrial inner membrane required for protein import into the mitochondrial matrix.

Q63327	MOBP_RAT	Myelin-associated oligodendrocyte basic protein	8551331	Molecular and developmental characterization of novel cDNAs of the myelin-associated/oligodendrocytic basic protein.

O55035	PPIG_RAT	Peptidyl-prolyl cis-trans isomerase G	9525923	Matrin CYP, an SR-rich cyclophilin that associates with the nuclear matrix and splicing factors.

Q06546	GABPA_HUMAN	GA-binding protein alpha chain	8441384	cDNA cloning of transcription factor E4TF1 subunits with Ets and notch motifs.

Q9M9F5	NCED9_ARATH	9-cis-epoxycarotenoid dioxygenase NCED9, chloroplastic	11532178	Regulation of drought tolerance by gene manipulation of 9-cis- epoxycarotenoid dioxygenase, a key enzyme in abscisic acid biosynthesis in Arabidopsis.

P02365	RS6_YEAST	40S ribosomal protein S6	15590835	The small-subunit processome is a ribosome assembly intermediate.

Q9BUB7	TMM70_HUMAN	Transmembrane protein 70, mitochondrial	18953340	TMEM70 mutations cause isolated ATP synthase deficiency and neonatal mitochondrial encephalocardiomyopathy.

A8K0Z3	WASH1_HUMAN	WAS protein family homolog 1	19922875	The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex.

P26038	MOES_HUMAN	Moesin	1924289	Moesin: a member of the protein 4.1-talin-ezrin family of proteins.

P32121	ARRB2_HUMAN	Beta-arrestin-2	15125834	Identification of beta-arrestin2 as a G protein-coupled receptor- stimulated regulator of NF-kappaB pathways.

P83859	OX26_HUMAN	Orexigenic neuropeptide QRFP	14657341	Identification of 26RFa, a hypothalamic neuropeptide of the RFamide peptide family with orexigenic activity.

Q9UTK5	ALM1_SCHPO	Abnormal long morphology protein 1	10660053	The alm1+ gene from Schizosaccharomyces pombe encodes a coiled-coil protein that associates with the medial region during mitosis.

O95835	LATS1_HUMAN	Serine/threonine-protein kinase LATS1	15122335	Tumor suppressor WARTS ensures genomic integrity by regulating both mitotic progression and G1 tetraploidy checkpoint function.

Q86V81	THOC4_HUMAN	THO complex subunit 4	18974867	Recruitment of the complete hTREX complex is required for Kaposi's sarcoma-associated herpesvirus intronless mRNA nuclear export and virus replication.

Q24211	STNA_DROME	Protein stoned-A	11069931	The products of the Drosophila stoned locus interact with synaptic vesicles via synaptotagmin.

P36877	2ABB_RAT	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform	12716901	A developmentally regulated, neuron-specific splice variant of the variable subunit Bbeta targets protein phosphatase 2A to mitochondria and modulates apoptosis.

Q12068	GRE2_YEAST	NADPH-dependent methylglyoxal reductase GRE2	12722185	Associating protein activities with their genes: rapid identification of a gene encoding a methylglyoxal reductase in the yeast Saccharomyces cerevisiae.

Q8WXX0	DYH7_HUMAN	Dynein heavy chain 7, axonemal	9373155	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

P39394	SYME_ECOLI	Toxic protein symE	17462020	An antisense RNA controls synthesis of an SOS-induced toxin evolved from an antitoxin.

Q7KHG2	JING_DROME	Zinc finger protein jing	16648585	Glial and neuronal functions of the Drosophila homolog of the human SWI/SNF gene ATR-X (DATR-X) and the jing zinc-finger gene specify the lateral positioning of longitudinal glia and axons.

Q7Z333	SETX_HUMAN	Probable helicase senataxin	17562789	Senataxin, defective in ataxia oculomotor apraxia type 2, is involved in the defense against oxidative DNA damage.

P63094	GNAS2_MOUSE	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	2826231	Identification of the lesion in the stimulatory GTP-binding protein of the uncoupled S49 lymphoma.

P11075	SEC7_YEAST	Protein transport protein SEC7	1986005	Localization of components involved in protein transport and processing through the yeast Golgi apparatus.

P81068	IRX1_MOUSE	Iroquois-class homeodomain protein IRX-1	17875669	The prepattern transcription factor Irx3 directs nephron segment identity.

Q2NKJ3	CTC1_HUMAN	CST complex subunit CTC1	19854131	Conserved telomere maintenance component 1 interacts with STN1 and maintains chromosome ends in higher eukaryotes.

Q10901	EAA1_CAEEL	Excitatory amino acid transporter	9178573	Structure and activity of a new form of the glutamate transporter of the nematode Caenorhabditis elegans.

Q1K9C2	MET5_SCHPO	Sulfite reductase [NADPH] subunit beta	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8H156	RAN3_ARATH	GTP-binding nuclear protein Ran-3	9025305	Characterization of proteins that interact with the GTP-bound form of the regulatory GTPase Ran in Arabidopsis.

Q92410	TPS1_CANAL	Alpha,alpha-trehalose-phosphate synthase [UDP-forming]	9683476	Disruption of the Candida albicans TPS1 gene encoding trehalose-6- phosphate synthase impairs formation of hyphae and decreases infectivity.

O15205	UBD_HUMAN	Ubiquitin D	16707496	The UBA domains of NUB1L are required for binding but not for accelerated degradation of the ubiquitin-like modifier FAT10.

Q9NBD7	CLASP_DROME	CLIP-associating protein	12538517	Orbit/Mast, the CLASP orthologue of Drosophila, is required for asymmetric stem cell and cystocyte divisions and development of the polarised microtubule network that interconnects oocyte and nurse cells during oogenesis.

Q70PP2	SMG1_DROME	Serine/threonine-protein kinase Smg1	15965240	Smg1 nonsense mutations do not abolish nonsense-mediated mRNA decay in Drosophila melanogaster.

Q8IZL2	MAML2_HUMAN	Mastermind-like protein 2	12370315	Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors.

P38710	INM1_YEAST	Inositol monophosphatase 1	12593845	Yeast inositol mono- and trisphosphate levels are modulated by inositol monophosphatase activity and nutrients.

P53048	MAL11_YEAST	General alpha-glucoside permease	12210897	Characterization of the putative maltose transporters encoded by YDL247w and YJR160c.

P84790	HBA_AYTFU	Hemoglobin subunit alpha-A	11829480	Molecular basis of bird respiration: primary hemoglobin structure component from Tufted duck (Aythya fuligula, Anseriformes)-role of alpha99Arg in formation of a complex salt bridge network.

P08463	CKS1_SCHPO	Cyclin-dependent kinases regulatory subunit	3322810	p13suc1 acts in the fission yeast cell division cycle as a component of the p34cdc2 protein kinase.

P11679	K2C8_MOUSE	Keratin, type II cytoskeletal 8	12857878	Keratin 20 helps maintain intermediate filament organization in intestinal epithelia.

Q9Y7L7	GPI15_SCHPO	Phosphatidylinositol N-acetylglucosaminyltransferase subunit gpi15	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9D3J8	AMTN_MOUSE	Amelotin	16304441	Amelotin -- a novel secreted, ameloblast-specific protein.

Q9GZS0	DNAI2_HUMAN	Dynein intermediate chain 2, axonemal	11153919	The human dynein intermediate chain 2 gene (DNAI2): cloning, mapping, expression pattern, and evaluation as a candidate for primary ciliary dyskinesia.

Q9Y285	SYFA_HUMAN	Phenylalanyl-tRNA synthetase alpha chain	9177188	Expression of a gene encoding a tRNA synthetase-like protein is enhanced in tumorigenic human myeloid leukemia cells and is cell cycle stage- and differentiation-dependent.

Q38890	GUN25_ARATH	Endoglucanase 25	18408158	Salt tolerance of Arabidopsis thaliana requires maturation of N- glycosylated proteins in the Golgi apparatus.

P87060	POP1_SCHPO	WD repeat-containing protein pop1	9472077	The Ste16 WD-repeat protein regulates cell-cycle progression under starvation through the Rum1 protein in Schizosaccharomyces pombe.

P0C2H7	RL27B_YEAST	60S ribosomal protein L27-B	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q03769	ENT5_YEAST	Epsin-5	12483220	Yeast epsin-related proteins required for Golgi-endosome traffic define a gamma-adaptin ear-binding motif.

P50995	ANX11_HUMAN	Annexin A11	18256029	Identification of Alix-type and non-Alix-type ALG-2-binding sites in human phospholipid scramblase 3: differential binding to an alternatively spliced isoform and amino acid-substituted mutants.

Q03012	SPP1_YEAST	COMPASS component SPP1	11687631	COMPASS: a complex of proteins associated with a trithorax-related SET domain protein.

O60784	TOM1_HUMAN	Target of Myb protein 1	10329004	TOM1 genes map to human chromosome 22q13.1 and mouse chromosome 8C1 and encode proteins similar to the endosomal proteins HGS and STAM.

P27449	VATL_HUMAN	V-type proton ATPase 16 kDa proteolipid subunit	1709739	CpG island in the region of an autosomal dominant polycystic kidney disease locus defines the 5' end of a gene encoding a putative proton channel.

P21580	TNAP3_HUMAN	Tumor necrosis factor alpha-induced protein 3	11463333	Isolation and characterization of two novel A20-like proteins.

O14920	IKKB_HUMAN	Inhibitor of nuclear factor kappa-B kinase subunit beta	19675099	Ro52-mediated monoubiquitination of IKK{beta} down-regulates NF-{kappa}B signalling.

O08838	AMPH_RAT	Amphiphysin	9348539	Amphiphysin heterodimers: potential role in clathrin-mediated endocytosis.

Q9NPA0	CO024_HUMAN	UPF0480 protein C15orf24	10873569	Characterization of five novel human genes in the 11q13-q22 region.

P32744	CLAS2_CAEEL	Protein CLASP-2	15854912	The CENP-F-like proteins HCP-1 and HCP-2 target CLASP to kinetochores to mediate chromosome segregation.

Q90XW6	IRX4A_XENLA	Iroquois-class homeodomain protein irx-4-A	18715948	A dual requirement for Iroquois genes during Xenopus kidney development.

Q55FK4	APT12_DICDI	Acyl-protein thioesterase 1 homolog 2	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

Q8BMJ8	SP8_MOUSE	Transcription factor Sp8	15358670	Sp8 and Sp9, two closely related buttonhead-like transcription factors, regulate Fgf8 expression and limb outgrowth in vertebrate embryos.

P82804	WIBG_DROME	Partner of Y14 and mago	12483225	An efficient protein complex purification method for functional proteomics in higher eukaryotes.

Q54ME1	GMSA_DICDI	Gamete and mating-type specific protein A	12963116	Construction of a gamete-enriched gene pool and RNAi-mediated functional analysis in Dictyostelium discoideum.

Q38890	GUN25_ARATH	Endoglucanase 25	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q8CCH7	FOG2_MOUSE	Zinc finger protein ZFPM2	9927675	Molecular cloning of FOG-2: a modulator of transcription factor GATA- 4 in cardiomyocytes.

P62841	RS15_HUMAN	40S ribosomal protein S15	2159154	Isolation and characterization of the human homologue of rig and its pseudogenes: the functional gene has features characteristic of housekeeping genes.

Q04174	SMP3_YEAST	GPI mannosyltransferase 4	2005867	Mutations in a Saccharomyces cerevisiae host showing increased holding stability of the heterologous plasmid pSR1.

Q9UKI2	BORG2_HUMAN	Cdc42 effector protein 3	11035016	A new family of Cdc42 effector proteins, CEPs, function in fibroblast and epithelial cell shape changes.

P36544	ACHA7_HUMAN	Neuronal acetylcholine receptor subunit alpha-7	8906617	Comparative structure of human neuronal alpha 2-alpha 7 and beta 2- beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits.

Q10135	LSD2_SCHPO	Lysine-specific histone demethylase 2	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

O00507	USP9Y_HUMAN	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y	9384609	Characterisation of the coding sequence and fine mapping of the human DFFRY gene and comparative expression analysis and mapping to the Sxrb interval of the mouse Y chromosome of the Dffry gene.

Q8MN58	CLC_DICDI	Clathrin light chain	14617352	Compromise of clathrin function and membrane association by clathrin light chain deletion.

Q95V55	FOXO_DROME	Forkhead box protein O	12893776	Control of cell number by Drosophila FOXO: downstream and feedback regulation of the insulin receptor pathway.

Q6R8J2	HEG_DANRE	Protein HEG	14680629	Heart of glass regulates the concentric growth of the heart in zebrafish.

P02545	LMNA_HUMAN	Prelamin-A/C	10080180	Mutations in the gene encoding lamin A/C cause autosomal dominant Emery-Dreifuss muscular dystrophy.

O75954	TSN9_HUMAN	Tetraspanin-9	10719184	Sequence and expression of seven new tetraspans.

O60687	SRPX2_HUMAN	Sushi repeat-containing protein SRPX2	18718938	Epileptic and developmental disorders of the speech cortex: ligand/receptor interaction of wild-type and mutant SRPX2 with the plasminogen activator receptor uPAR.

Q2M2T7	RT24_BOVIN	28S ribosomal protein S24, mitochondrial	11402041	Proteomic analysis of the mammalian mitochondrial ribosome. Identification of protein components in the 28S small subunit.

Q18677	DHP2_CAEEL	Dihydropyrimidinase 2	11167013	Cloning and characterization of the Caenorhabditis elegans CeCRMP/DHP-1 and -2; common ancestors of CRMP and dihydropyrimidinase?

P48552	NRIP1_HUMAN	Nuclear receptor-interacting protein 1	12773562	Regulation of subnuclear localization is associated with a mechanism for nuclear receptor corepression by RIP140.

Q9ULL4	PLXB3_HUMAN	Plexin-B3	15184888	Interplay between scatter factor receptors and B plexins controls invasive growth.

Q4U0Y4	NPL1A_XENLA	Nucleosome assembly protein 1-like 1-A	16982648	Identification of a structural and functional domain in xNAP1 involved in protein-protein interactions.

P40879	S26A3_HUMAN	Chloride anion exchanger	9554749	Clustering of private mutations in the congenital chloride diarrhea/down-regulated in adenoma gene.

Q6AXS5	PAIRB_RAT	Plasminogen activator inhibitor 1 RNA-binding protein	14988380	Involvement of an unnamed protein, RDA288, in the mechanism through which progesterone mediates its antiapoptotic action in spontaneously immortalized granulosa cells.

P38703	LAG1_YEAST	Sphingosine N-acyltransferase LAG1	11387200	C26-CoA-dependent ceramide synthesis of Saccharomyces cerevisiae is operated by Lag1p and Lac1p.

P83347	MGP_PRIGL	Matrix Gla protein	14668966	Characterization of osteocalcin (BGP) and matrix Gla protein (MGP) fish specific antibodies: validation for immunodetection studies in lower vertebrates.

Q9NYG5	APC11_HUMAN	Anaphase-promoting complex subunit 11	11739784	APC2 cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex.

Q10197	ALP1_SCHPO	Tubulin-folding cofactor D	10473641	Functional dissection and hierarchy of tubulin-folding cofactor homologues in fission yeast.

Q9VMR8	TOTM_DROME	Protein Turandot M	11409894	A family of Turandot-related genes in the humoral stress response of Drosophila.

P34144	RAC1A_DICDI	Rho-related protein rac1A	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P25580	PBN1_YEAST	Protein PBN1	9649520	The PBN1 gene of Saccharomyces cerevisiae: an essential gene that is required for the post-translational processing of the protease B precursor.

P22517	KCC2_YEAST	Calcium/calmodulin-dependent protein kinase II	2061341	Two yeast genes encoding calmodulin-dependent protein kinases. Isolation, sequencing and bacterial expressions of CMK1 and CMK2.

Q9AR19	GCN5_ARATH	Histone acetyltransferase GCN5	16603259	Physical and functional interactions of Arabidopsis ADA2 transcriptional coactivator proteins with the acetyltransferase GCN5 and with the cold-induced transcription factor CBF1.

P13609	SRGN_MOUSE	Serglycin	16046402	Serglycin-deficient cytotoxic T lymphocytes display defective secretory granule maturation and granzyme B storage.

P32797	CDC13_YEAST	Cell division control protein 13	7565765	Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint.

Q9LMP1	WAK2_ARATH	Wall-associated receptor kinase 2	10380805	A cluster of five cell wall-associated receptor kinase genes, Wak1-5, are expressed in specific organs of Arabidopsis.

Q9Z0R0	HASP_MOUSE	Serine/threonine-protein kinase haspin	10358056	Identification and characterization of a haploid germ cell-specific nuclear protein kinase (Haspin) in spermatid nuclei and its effects on somatic cells.

Q8K0C4	CP51A_MOUSE	Lanosterol 14-alpha demethylase	10864439	Characterization of the mouse lanosterol 14alpha-demethylase (CYP51), a new member of the evolutionarily most conserved cytochrome P450 family.

Q9UMX0	UBQL1_HUMAN	Ubiquilin-1	12095988	Role of ubiquilin associated with protein-disulfide isomerase in the endoplasmic reticulum in stress-induced apoptotic cell death.

P14780	MMP9_HUMAN	Matrix metalloproteinase-9	2551898	SV40-transformed human lung fibroblasts secrete a 92-kDa type IV collagenase which is identical to that secreted by normal human macrophages.

Q9Z272	GIT1_RAT	ARF GTPase-activating protein GIT1	9826657	Beta2-adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein.

P28033	CEBPB_MOUSE	CCAAT/enhancer-binding protein beta	19641492	Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-beta transcriptional complex.

Q14330	GPR18_HUMAN	N-arachidonyl glycine receptor	9205118	Cloning and chromosomal localization of a gene (GPR18) encoding a novel seven transmembrane receptor highly expressed in spleen and testis.

O28192	FLPA_ARCFU	Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase	12598892	Structure and function of archaeal box C/D sRNP core proteins.

P78540	ARGI2_HUMAN	Arginase-2, mitochondrial	8898077	Molecular cloning of cDNA for nonhepatic mitochondrial arginase (arginase II) and comparison of its induction with nitric oxide synthase in a murine macrophage-like cell line.

P21453	S1PR1_HUMAN	Sphingosine 1-phosphate receptor 1	9488656	Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1.

P84866	PLEUR_PLEOS	Pleurostatin	15941607	Pleurostrin, an antifungal peptide from the oyster mushroom.

Q6WWW4	UPL3_ARATH	E3 ubiquitin-protein ligase UPL3	10224275	Trichome cell growth in Arabidopsis thaliana can be derepressed by mutations in at least five genes.

P00746	CFAD_HUMAN	Complement factor D	1374388	Human adipsin is identical to complement factor D and is expressed at high levels in adipose tissue.

Q8IMX7	MIRO_DROME	Mitochondrial Rho GTPase	16055062	The GTPase dMiro is required for axonal transport of mitochondria to Drosophila synapses.

P24464	CP4AC_RAT	Cytochrome P450 4A12	11139583	Covalently linked heme in cytochrome P4504A fatty acid hydroxylases.

P0ACS7	RPIR_ECOLI	HTH-type transcriptional regulator rpiR	9401019	The D-allose operon of Escherichia coli K-12.

P49642	PRI1_HUMAN	DNA primase small subunit	8026492	DNA replication in vitro by recombinant DNA-polymerase-alpha- primase.

Q07093	GCYH_DROME	Head-specific guanylate cyclase	7797526	Two Drosophila genes that encode the alph and beta subunits of the brain soluble guanylyl cyclase.

P53913	FYV6_YEAST	Protein FYV6	14562095	Global analysis of protein localization in budding yeast.

P40457	MLP2_YEAST	Protein MLP2	10085285	Proteins connecting the nuclear pore complex with the nuclear interior.

O43283	M3K13_HUMAN	Mitogen-activated protein kinase kinase kinase 13	11726277	Mixed lineage kinase LZK forms a functional signaling complex with JIP-1, a scaffold protein of the c-Jun NH(2)-terminal kinase pathway.

P38991	IPL1_YEAST	Spindle assembly checkpoint kinase	11724818	Functional cooperation of Dam1, Ipl1, and the inner centromere protein (INCENP)-related protein Sli15 during chromosome segregation.

Q10322	DMA1_SCHPO	Probable E3 ubiquitin-protein ligase dma1	8978687	The fission yeast dma1 gene is a component of the spindle assembly checkpoint, required to prevent septum formation and premature exit from mitosis if spindle function is compromised.

Q03705	CG121_YEAST	Protein CGI121	16564010	A genome-wide screen identifies the evolutionarily conserved KEOPS complex as a telomere regulator.

O14905	WNT9B_HUMAN	Protein Wnt-9b	11604992	Molecular cloning and characterization of WNT14B, a novel member of the WNT gene family.

P23359	BMP7_MOUSE	Bone morphogenetic protein 7	14623234	Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot.

Q92560	BAP1_HUMAN	Ubiquitin carboxyl-terminal hydrolase BAP1	19117993	BRCA1-associated protein 1 interferes with BRCA1/BARD1 RING heterodimer activity.

P10041	DL_DROME	Neurogenic locus protein delta	15829515	The ubiquitin ligase Drosophila Mind bomb promotes Notch signaling by regulating the localization and activity of Serrate and Delta.

P47039	BNA3_YEAST	Probable kynurenine--oxoglutarate transaminase BNA3	18205391	Identification of formyl kynurenine formamidase and kynurenine aminotransferase from Saccharomyces cerevisiae using crystallographic, bioinformatic and biochemical evidence.

Q01855	RS15_YEAST	40S ribosomal protein S15	15167894	The ribosomal protein Rps15p is required for nuclear exit of the 40S subunit precursors in yeast.

Q8BW22	CREST_MOUSE	Calcium-responsive transactivator	14716005	Dendrite development regulated by CREST, a calcium-regulated transcriptional activator.

Q92377	MDM12_SCHPO	Mitochondrial distribution and morphology protein 12	9024686	Mdm12p, a component required for mitochondrial inheritance that is conserved between budding and fission yeast.

Q91783	KI11A_XENLA	Kinesin-like protein KIF11-A	8026619	The kinesin-related protein Eg5 associates with both interphase and spindle microtubules during Xenopus early development.

Q13426	XRCC4_HUMAN	DNA repair protein XRCC4	16439205	XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining.

Q9VBV3	TAKT_DROME	Protein takeout	12435630	The Drosophila takeout gene is regulated by the somatic sex- determination pathway and affects male courtship behavior.

P34441	EMB30_CAEEL	Abnormal embryogenesis protein 30	10749938	EMB-30: an APC4 homologue required for metaphase-to-anaphase transitions during meiosis and mitosis in Caenorhabditis elegans.

P76055	TTCA_ECOLI	tRNA 2-thiocytidine biosynthesis protein TtcA	14729701	The conserved Cys-X1-X2-Cys motif present in the TtcA protein is required for the thiolation of cytidine in position 32 of tRNA from Salmonella enterica serovar Typhimurium.

Q9P7J1	SWT1_SCHPO	Transcriptional protein swt1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q41963	TIP12_ARATH	Aquaporin TIP1-2	10102577	Characterization of two new channel protein genes in Arabidopsis.

P01086	IAAE_HORVU	Trypsin inhibitor CMe	7476859	The promoter of the gene Itr1 from barley confers a different tissue specificity in transgenic tobacco.

O15269	SPTC1_HUMAN	Serine palmitoyltransferase 1	19416851	Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities.

P97615	THIOM_RAT	Thioredoxin, mitochondrial	9006939	Cloning and expression of a novel mammalian thioredoxin.

O95278	EPM2A_HUMAN	Laforin	15930137	Insights into Lafora disease: malin is an E3 ubiquitin ligase that ubiquitinates and promotes the degradation of laforin.

P13988	TNSA_ECOLX	Transposon Tn7 transposition protein tnsA	10704304	A minimal system for Tn7 transposition: the transposon-encoded proteins TnsA and TnsB can execute DNA breakage and joining reactions that generate circularized Tn7 species.

Q9VMN5	CH60C_DROME	60 kDa heat shock protein homolog 2, mitochondrial	16385159	The Hsp60C gene in the 25F cytogenetic region in Drosophila melanogaster is essential for tracheal development and fertility.

P20963	CD3Z_HUMAN	T-cell surface glycoprotein CD3 zeta chain	11390434	The transmembrane adaptor protein TRIM regulates T-cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chain.

P83369	LSM11_HUMAN	U7 snRNA-associated Sm-like protein LSm11	11574479	Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein.

Q13241	KLRD1_HUMAN	Natural killer cells antigen CD94	7589107	Molecular characterization of human CD94: a type II membrane glycoprotein related to the C-type lectin superfamily.

O95157	NXPH3_HUMAN	Neurexophilin-3	9570794	Neurexophilins form a conserved family of neuropeptide-like glycoproteins.

O14031	OPT_SCHPO	Uncharacterized oligopeptide transporter C29B12.10c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9C5V6	TOP6B_ARATH	DNA topoisomerase 6 subunit B	16339310	RHL1 is an essential component of the plant DNA topoisomerase VI complex and is required for ploidy-dependent cell growth.

O60185	MTNA_SCHPO	Methylthioribose-1-phosphate isomerase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O42967	YB92_SCHPO	Uncharacterized ubiquitin-like protein C1E8.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9H6Y7	RN167_HUMAN	E3 ubiquitin-protein ligase RNF167	16314844	Tumor suppressor candidate TSSC5 is regulated by UbcH6 and a novel ubiquitin ligase RING105.

Q6SJ95	TBPL2_MOUSE	TATA box-binding protein-like protein 2	17704303	Switching of the core transcription machinery during myogenesis.

P51685	CCR8_HUMAN	C-C chemokine receptor type 8	8816377	Molecular cloning of TER1, a chemokine receptor-like gene expressed by lymphoid tissues.

Q9VS38	MED4_DROME	Mediator of RNA polymerase II transcription subunit 4	12021283	Novel Mediator proteins of the small Mediator complex in Drosophila SL2 cells.

O60683	PEX10_HUMAN	Peroxisome biogenesis factor 10	9700193	Mutations in PEX10 is the cause of Zellweger peroxisome deficiency syndrome of complementation group B.

Q5BD38	XGCA_EMENI	Oligoxyloglucan-reducing end-specific xyloglucanase	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

Q03956	RAV2_YEAST	Regulator of V-ATPase in vacuolar membrane protein 2	11283612	Skp1 forms multiple protein complexes, including RAVE, a regulator of V-ATPase assembly.

P43545	SNZ3_YEAST	Probable pyridoxine biosynthesis protein SNZ3	12271461	Functional analysis of yeast gene families involved in metabolism of vitamins B1 and B6.

P50110	SAM37_YEAST	Sorting assembly machinery 37 kDa subunit	12891361	Machinery for protein sorting and assembly in the mitochondrial outer membrane.

P19812	UBR1_YEAST	E3 ubiquitin-protein ligase UBR1	10688918	Physical association of ubiquitin ligases and the 26S proteasome.

Q15768	EFNB3_HUMAN	Ephrin-B3	9126477	cDNA cloning, chromosomal localization, and expression pattern of EPLG8, a new member of the EPLG gene family encoding ligands of EPH- related protein-tyrosine kinase receptors.

Q05567	SGPL_YEAST	Sphingosine-1-phosphate lyase	9334171	The BST1 gene of Saccharomyces cerevisiae is the sphingosine-1- phosphate lyase.

Q7TQA7	TA2R3_MOUSE	Taste receptor type 2 member 3	12734386	Evolutionary relationships of the Tas2r receptor gene families in mouse and human.

Q09761	SLD3_SCHPO	DNA replication regulator sld3	12006645	SpSld3 is required for loading and maintenance of SpCdc45 on chromatin in DNA replication in fission yeast.

Q8BKG3	PTK7_MOUSE	Tyrosine-protein kinase-like 7	15229603	PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates.

P51790	CLCN3_HUMAN	H(+)/Cl(-) exchange transporter 3	7665160	Characterization of a human and murine gene (CLCN3) sharing similarities to voltage-gated chloride channels and to a yeast integral membrane protein.

O54689	CCR6_MOUSE	C-C chemokine receptor type 6	9862452	Molecular cloning, functional characterization and mRNA expression analysis of the murine chemokine receptor CCR6 and its specific ligand MIP-3alpha.

P25588	MRC1_YEAST	Mediator of replication checkpoint protein 1	12944972	S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication- pausing complex.

Q9Y490	TLN1_HUMAN	Talin-1	10320340	Molecular interactions of N-RAP, a nebulin-related protein of striated muscle myotendon junctions and intercalated disks.

Q91731	SX11A_XENLA	Transcription factor Sox-11-A	12047350	Involvement of NLK and Sox11 in neural induction in Xenopus development.

O43684	BUB3_HUMAN	Mitotic checkpoint protein BUB3	10198256	Phosphorylation of human MAD1 by the BUB1 kinase in vitro.

Q91WZ8	DTBP1_MOUSE	Dysbindin	12923531	Hermansky-Pudlak syndrome type 7 (HPS-7) results from mutant dysbindin, a member of the biogenesis of lysosome-related organelles complex 1 (BLOC-1).

P05373	HEM2_YEAST	Delta-aminolevulinic acid dehydratase	2445751	Characterization of the yeast HEM2 gene and transcriptional regulation of COX5 and COR1 by heme.

Q13114	TRAF3_HUMAN	TNF receptor-associated factor 3	7527023	A novel RING finger protein interacts with the cytoplasmic domain of CD40.

Q9N1Q4	LAT2_RABIT	Large neutral amino acids transporter small subunit 2	10631289	Cloning and functional characterization of a Na(+)-independent, broad-specific neutral amino acid transporter from mammalian intestine.

O00780	VATE_DICDI	V-type proton ATPase subunit E	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P52910	ACS2_YEAST	Acetyl-coenzyme A synthetase 2	16857587	Nucleocytosolic acetyl-coenzyme a synthetase is required for histone acetylation and global transcription.

P0AD59	IVY_ECOLI	Inhibitor of vertebrate lysozyme	11278658	Escherichia coli ykfE ORFan gene encodes a potent inhibitor of C-type lysozyme.

P80422	LV212_HUMAN	Ig gamma lambda chain V-II region DOT	7737190	Characterization of the two unique human anti-flavin monoclonal immunoglobulins.

Q62685	NR1H3_RAT	Oxysterols receptor LXR-alpha	7935418	A novel orphan receptor specific for a subset of thyroid hormone- responsive elements and its interaction with the retinoid/thyroid hormone receptor subfamily.

Q9YGK8	IRX1A_XENLA	Iroquois-class homeodomain protein irx-1-A	19268445	The Xenopus Irx genes are essential for neural patterning and define the border between prethalamus and thalamus through mutual antagonism with the anterior repressors Fezf and Arx.

O74839	YC1B_SCHPO	Uncharacterized mscS family protein C1183.11	12529438	Global transcriptional responses of fission yeast to environmental stress.

P85247	CT111_LACTA	M-zodatoxin-Lt8h	18215128	Cyto-insectotoxins, a novel class of cytolytic and insecticidal peptides from spider venom.

Q94EJ6	PMTE_ARATH	Probable methyltransferase PMT14	16618929	Mapping the Arabidopsis organelle proteome.

Q6ZMB0	B3GN6_HUMAN	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6	11821425	Molecular cloning and characterization of a novel UDP-GlcNAc:GalNAc- peptide beta1,3-N-acetylglucosaminyltransferase (beta 3Gn-T6), an enzyme synthesizing the core 3 structure of O-glycans.

Q9M9M9	NDUAC_ARATH	Probable NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P15381	CAC1C_RABIT	Voltage-dependent L-type calcium channel subunit alpha-1C	17525370	Dominant negative suppression of Rad leads to QT prolongation and causes ventricular arrhythmias via modulation of L-type Ca2+ channels in the heart.

P32944	SWE1_YEAST	Mitosis inhibitor protein kinase SWE1	15282802	Localization of proteins that are coordinately expressed with Cln2 during the cell cycle.

Q9CQL4	RM20_MOUSE	39S ribosomal protein L20, mitochondrial	11279069	Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria.

P24350	IPOU_DROME	Inhibitory POU protein	1673230	I-POU: a POU-domain protein that inhibits neuron-specific gene activation.

Q9SWG3	FAR1_ARATH	Protein FAR-RED IMPAIRED RESPONSE 1	18033885	Transposase-derived transcription factors regulate light signaling in Arabidopsis.

Q6PDX6	RN220_MOUSE	E3 ubiquitin-protein ligase Rnf220	20170641	RNF220, an E3 ubiquitin ligase that targets Sin3B for ubiquitination.

Q07536	MMSA_BOVIN	Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial	8514806	Novel use of an iodo-myristyl-CoA analog identifies a semialdehyde dehydrogenase in bovine liver.

Q53GS7	GLE1_HUMAN	Nucleoporin GLE1	9618489	The human homologue of Saccharomyces cerevisiae Gle1p is required for poly(A)+ RNA export.

Q9HBH9	MKNK2_HUMAN	MAP kinase-interacting serine/threonine-protein kinase 2	11463832	Negative regulation of protein translation by mitogen-activated protein kinase-interacting kinases 1 and 2.

O96624	ARPC3_DICDI	Actin-related protein 2/3 complex subunit 3	17296313	Vectors for expression of proteins with single or combinatorial fluorescent protein and tandem affinity purification tags in Dictyostelium.

P21734	UBC1_YEAST	Ubiquitin-conjugating enzyme E2 1	10878801	A regulatory link between ER-associated protein degradation and the unfolded-protein response.

Q03824	INP2_YEAST	Inheritance of peroxisomes protein 2	14562095	Global analysis of protein localization in budding yeast.

Q9NPH9	IL26_HUMAN	Interleukin-26	10729163	Induction of a novel cellular homolog of interleukin-10, AK155, by transformation of T lymphocytes with herpesvirus saimiri.

P86193	MYXC2_CRODM	Crotamine-IV-2	17828447	Structural and biological characterization of two crotamine isoforms IV-2 and IV-3 isolated from the Crotalus durissus cumanensis venom.

P15431	GBRB1_RAT	Gamma-aminobutyric acid receptor subunit beta-1	2548852	GABAA receptor beta subunit heterogeneity: functional expression of cloned cDNAs.

Q8CJ78	ZN628_MOUSE	Zinc finger protein 628	15556296	ZEC, a zinc finger protein with novel binding specificity and transcription regulatory activity.

P14780	MMP9_HUMAN	Matrix metalloproteinase-9	16512877	Extracellular matrix protein 1 inhibits the activity of matrix metalloproteinase 9 through high-affinity protein/protein interactions.

Q9Y2T2	AP3M1_HUMAN	AP-3 complex subunit mu-1	10024875	Altered trafficking of lysosomal proteins in Hermansky-Pudlak syndrome due to mutations in the beta 3A subunit of the AP-3 adaptor.

Q9UNH5	CC14A_HUMAN	Dual specificity protein phosphatase CDC14A	9367992	A family of putative tumor suppressors is structurally and functionally conserved in humans and yeast.

Q9DCI9	RM32_MOUSE	39S ribosomal protein L32, mitochondrial	11279069	Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria.

P11632	NHP6A_YEAST	Non-histone chromosomal protein 6A	12952948	Multiple Nhp6 molecules are required to recruit Spt16-Pob3 to form yFACT complexes and to reorganize nucleosomes.

Q9M024	TAAC_ARATH	Thylakoid ADP,ATP carrier protein, chloroplastic	17261580	Identification, expression, and functional analyses of a thylakoid ATP/ADP carrier from Arabidopsis.

P32834	SXA1_SCHPO	Aspartic proteinase sxa1	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

Q8S944	DRP3A_ARATH	Dynamin-related protein 3A	9747851	Molecular cloning of an Arabidopsis cDNA encoding a dynamin-like protein that is localized to plastids.

O95644	NFAC1_HUMAN	Nuclear factor of activated T-cells, cytoplasmic 1	8202141	NF-AT components define a family of transcription factors targeted in T-cell activation.

P04637	P53_HUMAN	Cellular tumor antigen p53	20173098	RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage.

Q9Z137	B3GA2_RAT	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2	10082676	Molecular cloning and expression of a second glucuronyltransferase involved in the biosynthesis of the HNK-1 carbohydrate epitope.

Q60571	CRHBP_MOUSE	Corticotropin-releasing factor-binding protein	7556876	Molecular and biochemical characterization of the mouse brain corticotropin-releasing hormone-binding protein.

Q61781	K1C14_MOUSE	Keratin, type I cytoskeletal 14	16702408	Keratin 17 modulates hair follicle cycling in a TNFalpha-dependent fashion.

O49048	VPS45_ARATH	Vacuolar protein sorting-associated protein 45 homolog	10888666	AtVPS45 complex formation at the trans-Golgi network.

Q12791	KCMA1_HUMAN	Calcium-activated potassium channel subunit alpha-1	11880513	Cloning and characterization of glioma BK, a novel BK channel isoform highly expressed in human glioma cells.

O00337	S28A1_HUMAN	Sodium/nucleoside cotransporter 1	9124315	Molecular cloning and functional expression of cDNAs encoding a human Na+-nucleoside cotransporter (hCNT1).

O95202	LETM1_HUMAN	LETM1 and EF-hand domain-containing protein 1, mitochondrial	10486213	LETM1, a novel gene encoding a putative EF-hand Ca(2+)-binding protein, flanks the Wolf-Hirschhorn syndrome (WHS) critical region and is deleted in most WHS patients.

Q9SV84	NIP51_ARATH	Probable aquaporin NIP5-1	16679457	The Arabidopsis major intrinsic protein NIP5;1 is essential for efficient boron uptake and plant development under boron limitation.

Q9Y572	RIPK3_HUMAN	Receptor-interacting serine/threonine-protein kinase 3	10358032	RIP3, a novel apoptosis-inducing kinase.

Q13402	MYO7A_HUMAN	Myosin-VIIa	15300860	Impaired calmodulin binding of myosin-7A causes autosomal dominant hearing loss (DFNA11).

P06127	CD5_HUMAN	T-cell surface glycoprotein CD5	3093892	Isolation of complementary DNA clones encoding the human lymphocyte glycoprotein T1/Leu-1.

Q22866	TPM1_CAEEL	Tropomyosin isoforms a/b/d/f	15930100	Muscle arm development in Caenorhabditis elegans.

Q9NV06	DCA13_HUMAN	DDB1- and CUL4-associated factor 13	16949367	A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1.

Q99729	ROAA_HUMAN	Heterogeneous nuclear ribonucleoprotein A/B	1717314	Cloning and sequence analysis of a human type A/B hnRNP protein.

P53722	ATP23_YEAST	Mitochondrial inner membrane protease ATP23	17135288	Prohibitins interact genetically with Atp23, a novel processing peptidase and chaperone for the F1F0-ATP synthase.

P87143	YDMD_SCHPO	Uncharacterized RNA-binding protein C57A7.13	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O01498	STAM1_CAEEL	Signal transducing adapter molecule 1	16824915	Galphao/i and Galphas signaling function in parallel with the MSP/Eph receptor to control meiotic diapause in C. elegans.

P42073	REF2_YEAST	RNA end formation protein 2	7862160	REF2 encodes an RNA-binding protein directly involved in yeast mRNA 3'-end formation.

Q9JHZ2	ANKH_MOUSE	Progressive ankylosis protein	10894769	Role of the mouse ank gene in control of tissue calcification and arthritis.

Q9FUJ1	CKX7_ARATH	Cytokinin dehydrogenase 7	12721786	Structure and function of cytokinin oxidase/dehydrogenase genes of maize, rice, Arabidopsis and other species.

Q08629	TICN1_HUMAN	Testican-1	8389704	Testican, a multidomain testicular proteoglycan resembling modulators of cell social behaviour.

Q9NR33	DPOE4_HUMAN	DNA polymerase epsilon subunit 4	10801849	Identification and cloning of two histone fold motif-containing subunits of HeLa DNA polymerase epsilon.

Q91V27	MELPH_MOUSE	Melanophilin	18940604	Structural basis for the exclusive specificity of Slac2- a/melanophilin for the Rab27 GTPases.

P70245	EBP_MOUSE	3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	8798407	Emopamil-binding protein, a mammalian protein that binds a series of structurally diverse neuroprotective agents, exhibits delta8-delta7 sterol isomerase activity in yeast.

Q8JHV9	BIR7A_XENLA	Baculoviral IAP repeat-containing protein 7-A	15853809	Apoptosis-inhibiting activities of BIR family proteins in Xenopus egg extracts.

O95202	LETM1_HUMAN	LETM1 and EF-hand domain-containing protein 1, mitochondrial	18628306	Characterization of the mitochondrial protein LETM1, which maintains the mitochondrial tubular shapes and interacts with the AAA-ATPase BCS1L.

O42478	TLE4_XENLA	Transducin-like enhancer protein 4	17577580	Bowline mediates association of the transcriptional corepressor XGrg- 4 with Tbx6 during somitogenesis in Xenopus.

O95467	GNAS3_HUMAN	Neuroendocrine secretory protein 55	10729789	Neuroendocrine secretory protein 55 (NESP55): alternative splicing onto transcripts of the GNAS gene and posttranslational processing of a maternally expressed protein.

P25867	UBCD1_DROME	Ubiquitin-conjugating enzyme E2-17 kDa	1310935	Drosophila UbcD1 encodes a highly conserved ubiquitin-conjugating enzyme involved in selective protein degradation.

Q61496	DDX4_MOUSE	Probable ATP-dependent RNA helicase DDX4	17141210	Tudor-related proteins TDRD1/MTR-1, TDRD6 and TDRD7/TRAP: domain composition, intracellular localization, and function in male germ cells in mice.

Q06706	ELP1_YEAST	Elongator complex protein 1	11689709	Characterization of a six-subunit holo-elongator complex required for the regulated expression of a group of genes in Saccharomyces cerevisiae.

Q9VRP5	UBP36_DROME	Ubiquitin carboxyl-terminal hydrolase 36	19039105	Drosophila stem cells share a common requirement for the histone H2B ubiquitin protease scrawny.

Q9UMZ2	SYNRG_HUMAN	Synergin gamma	10477754	Gamma-synergin: an EH domain-containing protein that interacts with gamma-adaptin.

P13942	COBA2_HUMAN	Collagen alpha-2(XI) chain	16033917	Mutation of COL11A2 causes autosomal recessive non-syndromic hearing loss at the DFNB53 locus.

Q13045	FLII_HUMAN	Protein flightless-1 homolog	10366446	Novel proteins interacting with the leucine-rich repeat domain of human flightless-I identified by the yeast two-hybrid system.

O95832	CLD1_HUMAN	Claudin-1	9647647	Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin.

O54852	KCNH7_RAT	Potassium voltage-gated channel subfamily H member 7	9390998	Identification of two nervous system-specific members of the erg potassium channel gene family.

P55284	CADH5_MOUSE	Cadherin-5	12234928	VE-PTP and VE-cadherin ectodomains interact to facilitate regulation of phosphorylation and cell contacts.

P37702	BGL38_ARATH	Myrosinase 1	19433491	Myrosinases, TGG1 and TGG2, redundantly function in ABA and MeJA signaling in Arabidopsis guard cells.

Q9DCB1	HMGN3_MOUSE	High mobility group nucleosome-binding domain-containing protein 3	11356838	HMGN3a and HMGN3b, two protein isoforms with a tissue-specific expression pattern, expand the cellular repertoire of nucleosome- binding proteins.

P53286	BTN2_YEAST	Protein BTN2	15701790	Interaction among Btn1p, Btn2p, and Ist2p reveals potential interplay among the vacuole, amino acid levels, and ion homeostasis in the yeast Saccharomyces cerevisiae.

Q8JG70	AA2DA_DANRE	Alpha-2Da adrenergic receptor	15655522	Conserved structural, pharmacological and functional properties among the three human and five zebrafish alpha2-adrenoceptors.

Q39232	SUC1_ARATH	Sucrose transport protein SUC1	9307438	A kinetic model with ordered cytoplasmic dissociation for SUC1, an Arabidopsis H(+)/sucrose cotransporter expressed in Xenopus oocytes.

O60096	RT35_SCHPO	37S ribosomal protein S35, mitochondrial	18245278	Bot1p is required for mitochondrial translation, respiratory function, and normal cell morphology in the fission yeast Schizosaccharomyces pombe.

P35916	VGFR3_HUMAN	Vascular endothelial growth factor receptor 3	10835628	Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema.

Q61496	DDX4_MOUSE	Probable ATP-dependent RNA helicase DDX4	16787967	Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway?

Q9JJK5	HERP1_MOUSE	Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein	10922362	Herp, a new ubiquitin-like membrane protein induced by endoplasmic reticulum stress.

Q28250	SPCS2_CANFA	Signal peptidase complex subunit 2	3511473	Purification of microsomal signal peptidase as a complex.

Q5AWI5	AGDC_EMENI	Alpha/beta-glucosidase agdC	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

P10276	RARA_HUMAN	Retinoic acid receptor alpha	2825025	A human retinoic acid receptor which belongs to the family of nuclear receptors.

Q2M389	WAHS7_HUMAN	WASH complex subunit 7	19922875	The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex.

Q9ZQ94	COGT3_ARATH	Cytokinin-O-glucosyltransferase 3	16214889	The UGT73C5 of Arabidopsis thaliana glucosylates brassinosteroids.

Q9UW12	PALA_CANAL	pH-response regulator protein palA/RIM20	10629054	RIM101-dependent and -independent pathways govern pH responses in Candida albicans.

P81641	AMYB_DROME	Alpha-amylase B	11156987	Molecular evolution of duplicated amylase gene regions in Drosophila melanogaster: evidence of positive selection in the coding regions and selective constraints in the cis-regulatory regions.

Q9W0K7	BAB1_DROME	Protein bric-a-brac 1	11973274	The bric a brac locus consists of two paralogous genes encoding BTB/POZ domain proteins and acts as a homeotic and morphogenetic regulator of imaginal development in Drosophila.

P13405	RB_MOUSE	Retinoblastoma-associated protein	11571651	Association of UNP, a ubiquitin-specific protease, with the pocket proteins pRb, p107 and p130.

P25333	HAL4_YEAST	Serine/threonine-protein kinase HAL4/SAT4	10207057	A novel mechanism of ion homeostasis and salt tolerance in yeast: the Hal4 and Hal5 protein kinases modulate the Trk1-Trk2 potassium transporter.

Q9LZM8	BLH9_ARATH	BEL1-like homeodomain protein 9	15120075	Competence to respond to floral inductive signals requires the homeobox genes PENNYWISE and POUND-FOOLISH.

P36104	SWD2_YEAST	COMPASS component SWD2	11687631	COMPASS: a complex of proteins associated with a trithorax-related SET domain protein.

Q01664	TFAP4_HUMAN	Transcription factor AP-4	2123466	Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity.

P31414	AVP1_ARATH	Pyrophosphate-energized vacuolar membrane proton pump 1	15215502	Isolation of intact vacuoles and proteomic analysis of tonoplast from suspension-cultured cells of Arabidopsis thaliana.

O14944	EREG_HUMAN	Proepiregulin	9337852	Distribution of mRNA for human epiregulin, a differentially expressed member of the epidermal growth factor family.

Q54XG7	DIMA_DICDI	Basic-leucine zipper transcription factor A	16410410	bZIP transcription factor interactions regulate DIF responses in Dictyostelium.

O74803	RHP23_SCHPO	UV excision repair protein rhp23	12560082	Ubiquitin binding proteins protect ubiquitin conjugates from disassembly.

Q10659	SPO14_SCHPO	Membrane glycoprotein spo14	12631727	The fission yeast spo14(+) gene encoding a functional homologue of budding yeast Sec12 is required for the development of forespore membranes.

Q96D31	CRCM1_HUMAN	Calcium release-activated calcium channel protein 1	17905723	STIM2 protein mediates distinct store-dependent and store-independent modes of CRAC channel activation.

P47045	TIM54_YEAST	Mitochondrial import inner membrane translocase subunit TIM54	9412462	The Tim54p-Tim22p complex mediates insertion of proteins into the mitochondrial inner membrane.

P12754	EI2BD_YEAST	Translation initiation factor eIF-2B subunit delta	8506384	A protein complex of translational regulators of GCN4 mRNA is the guanine nucleotide-exchange factor for translation initiation factor 2 in yeast.

Q9R0M1	XCR1_MOUSE	Chemokine XC receptor 1	10518929	Molecular cloning of mXCR1, the murine SCM-1/lymphotactin receptor.

Q9VTM5	TFB1M_DROME	Dimethyladenosine transferase 1, mitochondrial	15749697	Drosophila mitochondrial transcription factor B1 modulates mitochondrial translation but not transcription or DNA copy number in Schneider cells.

Q8WXG9	GPR98_HUMAN	G-protein coupled receptor 98	12402266	A nonsense mutation of the MASS1 gene in a family with febrile and afebrile seizures.

Q3ZEJ6	SPA33_BOVIN	Serpin A3-3	16716310	Purification of the skeletal muscle protein endopin 1B and characterization of the genes encoding endopin 1A and 1B isoforms.

Q9Y698	CCG2_HUMAN	Voltage-dependent calcium channel gamma-2 subunit	10221464	Identification and cloning of putative human neuronal voltage-gated calcium channel gamma-2 and gamma-3 subunits: neurologic implications.

Q8AXB3	VGFR4_DANRE	Vascular endothelial growth factor receptor kdr-like	17698971	Duplicate VegfA genes and orthologues of the KDR receptor tyrosine kinase family mediate vascular development in the zebrafish.

P31385	DEP1_YEAST	Transcriptional regulatory protein DEP1	16314178	Stable incorporation of sequence specific repressors Ash1 and Ume6 into the Rpd3L complex.

P53688	HST4_YEAST	NAD-dependent histone deacetylase HST4	14562095	Global analysis of protein localization in budding yeast.

P78330	SERB_HUMAN	Phosphoserine phosphatase	9188776	Human L-3-phosphoserine phosphatase: sequence, expression and evidence for a phosphoenzyme intermediate.

Q9Y5I4	PCDC2_HUMAN	Protocadherin alpha-C2	10380929	A striking organization of a large family of human neural cadherin- like cell adhesion genes.

P81172	HEPC_HUMAN	Hepcidin	11113131	Hepcidin: a urinary antimicrobial peptide synthesized in the liver.

Q9PVY9	FXC2A_XENLA	Forkhead box protein C2-A	11291856	Fox (forkhead) genes are involved in the dorso-ventral patterning of the Xenopus mesoderm.

Q3UW53	NIBAN_MOUSE	Protein Niban	17588536	The endoplasmic reticulum stress-inducible protein Niban regulates eIF2alpha and S6K1/4E-BP1 phosphorylation.

Q9N337	MED6_CAEEL	Mediator of RNA polymerase II transcription subunit 6	10611325	Caenorhabditis elegans mediator complexes are required for developmental-specific transcriptional activation.

P87152	YB0B_SCHPO	Bromodomain-containing protein C25H2.11c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O94262	YORD_SCHPO	Putative uncharacterized membrane protein P8B7.13	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

B7ZS96	TTHY_XENLA	Transthyretin	12228058	Crocodile transthyretin: structure, function, and evolution.

P47888	OR3A3_HUMAN	Olfactory receptor 3A3	8004088	Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire.

Q9WTZ1	RBX2_MOUSE	RING-box protein 2	10082581	SAG, a novel zinc RING finger protein that protects cells from apoptosis induced by redox agents.

Q8BJ66	KAZD1_MOUSE	Kazal-type serine protease inhibitor domain-containing protein 1	18757743	Transcriptome-based systematic identification of extracellular matrix proteins.

Q9LV33	BGL44_ARATH	Beta-glucosidase 44	15604686	Functional genomic analysis of Arabidopsis thaliana glycoside hydrolase family 1.

Q9UKA1	FBXL5_HUMAN	F-box/LRR-repeat protein 5	10531035	Identification of a family of human F-box proteins.

O80605	SUC3_ARATH	Sucrose transport protein SUC3	14739351	Wounding enhances expression of AtSUC3, a sucrose transporter from Arabidopsis sieve elements and sink tissues.

Q5T4B2	GT253_HUMAN	Glycosyltransferase 25 family member 3	10608765	Cerebral cell adhesion molecule: a novel leukocyte adhesion determinant on blood-brain barrier capillary endothelium.

P98177	FOXO4_HUMAN	Forkhead box protein O4	10783894	AFX-like forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1.

O82794	AGL24_ARATH	MADS-box protein AGL24	18466303	SOC1 translocated to the nucleus by interaction with AGL24 directly regulates leafy.

O04983	ACCC_ARATH	Biotin carboxylase, chloroplastic	16207701	The oligomeric stromal proteome of Arabidopsis thaliana chloroplasts.

Q13137	CACO2_HUMAN	Calcium-binding and coiled-coil domain-containing protein 2	7540613	Molecular characterization of NDP52, a novel protein of the nuclear domain 10, which is redistributed upon virus infection and interferon treatment.

Q9UUD1	SREBP_SCHPO	Sterol regulatory element-binding protein 1	15797383	SREBP pathway responds to sterols and functions as an oxygen sensor in fission yeast.

P21452	NK2R_HUMAN	Substance-K receptor	2173708	The human neurokinin A (substance K) receptor. Molecular cloning of the gene, chromosome localization, and isolation of cDNA from tracheal and gastric tissues.

Q9H3N8	HRH4_HUMAN	Histamine H4 receptor	10973974	Molecular cloning and characterization of a novel type of histamine receptor preferentially expressed in leukocytes.

Q9SN43	CIPKC_ARATH	CBL-interacting serine/threonine-protein kinase 12	11230129	The NAF domain defines a novel protein-protein interaction module conserved in Ca(2+)-regulated kinases.

Q9NJP9	GLPK_TRYBB	Glycerol kinase, glycosomal	11154065	Cloning, heterologous expression and kinetic analysis of glycerol kinase (TbGLK1) from Trypanosoma brucei.

Q8IU80	TMPS6_HUMAN	Transmembrane protease serine 6	12149247	Matriptase-2, a membrane-bound mosaic serine proteinase predominantly expressed in human liver and showing degrading activity against extracellular matrix proteins.

P53738	TR112_YEAST	Multifunctional methyltransferase subunit TRM112	17008308	The zinc finger protein Ynr046w is plurifunctional and a component of the eRF1 methyltransferase in yeast.

Q8IUH5	ZDH17_HUMAN	Palmitoyltransferase ZDHHC17	18794299	Huntingtin-interacting proteins, HIP14 and HIP14L, mediate dual functions, palmitoyl acyltransferase and Mg2+ transport.

Q03758	BUL2_YEAST	Ubiquitin ligase-binding protein BUL2	11352928	Components of a ubiquitin ligase complex specify polyubiquitination and intracellular trafficking of the general amino acid permease.

P0A817	METK_ECOLI	S-adenosylmethionine synthase	7629147	Investigation of monovalent cation activation of S-adenosylmethionine synthetase using mutagenesis and uranyl inhibition.

Q9DG12	ARNT2_DANRE	Aryl hydrocarbon receptor nuclear translocator 2	10960127	Overexpression of a zebrafish ARNT2-like factor represses CYP1A transcription in ZLE cells.

P15151	PVR_HUMAN	Poliovirus receptor	2170108	The poliovirus receptor protein is produced both as membrane-bound and secreted forms.

Q28204	KCMA1_BOVIN	Calcium-activated potassium channel subunit alpha-1	8973172	An evolutionarily conserved binding site for serine proteinase inhibitors in large conductance calcium-activated potassium channels.

Q9Z0F6	RAD9A_MOUSE	Cell cycle checkpoint control protein RAD9A	9766521	Molecular cloning and tissue-specific expression of Mrad9, a murine orthologue of the Schizosaccharomyces pombe rad9+ checkpoint control gene.

Q96EQ9	PRDM9_MOUSE	Histone-lysine N-methyltransferase PRDM9	16292313	A histone H3 methyltransferase controls epigenetic events required for meiotic prophase.

Q8K1Q4	PRIP1_RAT	ProSAP-interacting protein 1	16522626	ProSAP-interacting protein 1 (ProSAPiP1), a novel protein of the postsynaptic density that links the spine-associated Rap-Gap (SPAR) to the scaffolding protein ProSAP2/Shank3.

Q7K2Y9	NTAQ1_DROME	Protein N-terminal glutamine amidohydrolase	12593794	The staufen/pumilio pathway is involved in Drosophila long-term memory.

P58012	FOXL2_HUMAN	Forkhead box protein L2	16153597	Transcriptional factor FOXL2 interacts with DP103 and induces apoptosis.

O70514	FGFP1_MOUSE	Fibroblast growth factor-binding protein 1	15806171	The fibroblast growth factor binding protein is a novel interaction partner of FGF-7, FGF-10 and FGF-22 and regulates FGF activity: implications for epithelial repair.

P33760	PEX6_YEAST	Peroxisomal ATPase PEX6	12808025	Pex15p of Saccharomyces cerevisiae provides a molecular basis for recruitment of the AAA peroxin Pex6p to peroxisomal membranes.

Q8IM04	YPF04_PLAF7	Uncharacterized protein PF14_0089	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

Q9FQ02	XRN2_ARATH	5'-3' exoribonuclease 2	11106401	Novel features of the XRN-family in Arabidopsis: evidence that AtXRN4, one of several orthologs of nuclear Xrn2p/Rat1p, functions in the cytoplasm.

P27515	URK1_YEAST	Uridine kinase	14562095	Global analysis of protein localization in budding yeast.

O95498	VNN2_HUMAN	Vascular non-inflammatory molecule 2	11491533	Vanin genes are clustered (human 6q22-24 and mouse 10A2B1) and encode isoforms of pantetheinase ectoenzymes.

Q12929	EPS8_HUMAN	Epidermal growth factor receptor kinase substrate 8	8084614	Evolutionary conservation of the EPS8 gene and its mapping to human chromosome 12q23-q24.

P02793	FRIL1_RAT	Ferritin light chain 1	3584116	Characterization and evolution of the expressed rat ferritin light subunit gene and its pseudogene family. Conservation of sequences within noncoding regions of ferritin genes.

P09758	TACD2_HUMAN	Tumor-associated calcium signal transducer 2	10192395	Identification of the gene responsible for gelatinous drop-like corneal dystrophy.

Q12176	MAK21_YEAST	Ribosome biogenesis protein MAK21	11371346	Maturation and intranuclear transport of pre-ribosomes requires Noc proteins.

O54965	RNF13_MOUSE	E3 ubiquitin-protein ligase RNF13	19292867	The PA-TM-RING protein RING finger protein 13 is an endosomal integral membrane E3 ubiquitin ligase whose RING finger domain is released to the cytoplasm by proteolysis.

Q9LME2	SYCP1_ARATH	Synaptonemal complex protein 1	16230536	The Arabidopsis synaptonemal complex protein ZYP1 is required for chromosome synapsis and normal fidelity of crossing over.

P84796	ALLIU_ALLSA	Alliumin	15629528	Isolation of alliumin, a novel protein with antimicrobial and antiproliferative activities from multiple-cloved garlic bulbs.

P12956	XRCC6_HUMAN	X-ray repair cross-complementing protein 6	20383123	Ku is a 5'-dRP/AP lyase that excises nucleotide damage near broken ends.

P23615	SPT6_YEAST	Transcription elongation factor SPT6	9450930	Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae.

P40960	PAC11_YEAST	WD repeat-containing protein PAC11	11266443	Cortical Num1p interacts with the dynein intermediate chain Pac11p and cytoplasmic microtubules in budding yeast.

P19793	RXRA_HUMAN	Retinoic acid receptor RXR-alpha	1310260	9-cis retinoic acid is a high affinity ligand for the retinoid X receptor.

Q99JR1	SFXN1_MOUSE	Sideroflexin-1	11274051	A mutation in a mitochondrial transmembrane protein is responsible for the pleiotropic hematological and skeletal phenotype of flexed- tail (f/f) mice.

P35193	ATG19_YEAST	Autophagy-related protein 19	11430817	Cvt19 is a receptor for the cytoplasm-to-vacuole targeting pathway.

Q9PT60	RBP1A_XENLA	RalA-binding protein 1-A	15511640	RLIP mediates downstream signalling from RalB to the actin cytoskeleton during Xenopus early development.

P47050	CUL8_YEAST	Regulator of Ty1 transposition protein 101	12676951	A role for Saccharomyces cerevisiae Cul8 ubiquitin ligase in proper anaphase progression.

Q9BUP3	HTAI2_HUMAN	Oxidoreductase HTATIP2	9174052	A link between metastasis and resistance to apoptosis of variant small cell lung carcinoma.

Q15835	RK_HUMAN	Rhodopsin kinase	9020843	Defects in the rhodopsin kinase gene in the Oguchi form of stationary night blindness.

Q9YGK8	IRX1A_XENLA	Iroquois-class homeodomain protein irx-1-A	14681193	Interplay between Notch signaling and the homeoprotein Xiro1 is required for neural crest induction in Xenopus embryos.

P36116	VPS51_YEAST	Vacuolar protein sorting-associated protein 51	12686613	Vps51p mediates the association of the GARP (Vps52/53/54) complex with the late Golgi t-SNARE Tlg1p.

P13286	PHKG1_RAT	Phosphorylase b kinase gamma catalytic chain, skeletal muscle isoform	8419323	Characterization of the gene for rat phosphorylase kinase catalytic subunit.

P40228	CSK2B_ARATH	Casein kinase II subunit beta	9724822	Protein kinase CK2 interacts with and phosphorylates the Arabidopsis circadian clock-associated 1 protein.

Q6VUC1	DPH3_CRIGR	DPH3 homolog	14527407	Retroviral insertional mutagenesis identifies a small protein required for synthesis of diphthamide, the target of bacterial ADP- ribosylating toxins.

Q91ZD4	VANG2_MOUSE	Vang-like protein 2	12724779	Identification of Vangl2 and Scrb1 as planar polarity genes in mammals.

Q05153	SSRP1_ARATH	FACT complex subunit SSRP1	15546350	The chromatin remodelling complex FACT associates with actively transcribed regions of the Arabidopsis genome.

P36107	AUR1_YEAST	Inositol phosphorylceramide synthase	9092515	Sphingolipid synthesis as a target for antifungal drugs. Complementation of the inositol phosphorylceramide synthase defect in a mutant strain of Saccharomyces cerevisiae by the AUR1 gene.

Q8NFP4	MDGA1_HUMAN	MAM domain-containing glycosylphosphatidylinositol anchor protein 1	15922729	Characterization of MDGA1, a novel human glycosylphosphatidylinositol-anchored protein localized in lipid rafts.

A2AD83	FRMD7_MOUSE	FERM domain-containing protein 7	19892780	The nystagmus-associated FRMD7 gene regulates neuronal outgrowth and development.

Q9EQZ6	RPGF4_MOUSE	Rap guanine nucleotide exchange factor 4	18660803	Structure of Epac2 in complex with a cyclic AMP analogue and RAP1B.

Q9VH90	TRBID_DROME	Ubiquitin thioesterase trabid	18281465	Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains.

P21912	DHSB_HUMAN	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial	2302193	Human complex II (succinate-ubiquinone oxidoreductase): cDNA cloning of iron sulfur (Ip) subunit of liver mitochondria.

Q9UI42	CBPA4_HUMAN	Carboxypeptidase A4	10383164	Carboxypeptidase A3 (CPA3): a novel gene highly induced by histone deacetylase inhibitors during differentiation of prostate epithelial cancer cells.

Q99742	NPAS1_HUMAN	Neuronal PAS domain-containing protein 1	9012850	Molecular characterization of two mammalian bHLH-PAS domain proteins selectively expressed in the central nervous system.

P21941	MATN1_HUMAN	Cartilage matrix protein	15075323	Interactions between the cartilage oligomeric matrix protein and matrilins. Implications for matrix assembly and the pathogenesis of chondrodysplasias.

Q9XFD1	NCBP2_ARATH	Nuclear cap-binding protein subunit 2	18550839	Dual roles of the nuclear cap-binding complex and SERRATE in pre-mRNA splicing and microRNA processing in Arabidopsis thaliana.

Q05871	ECI1_YEAST	3,2-trans-enoyl-CoA isomerase	9837886	Molecular characterization of Saccharomyces cerevisiae Delta3, Delta2-enoyl-CoA isomerase.

Q9WVL7	CXL15_MOUSE	C-X-C motif chemokine 15	10228029	Lungkine, a novel CXC chemokine, specifically expressed by lung bronchoepithelial cells.

Q93038	TNR25_HUMAN	Tumor necrosis factor receptor superfamily member 25	8875942	Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95.

Q9SK82	COGT2_ARATH	Cytokinin-O-glucosyltransferase 2	15342621	N-glucosylation of cytokinins by glycosyltransferases of Arabidopsis thaliana.

Q924S5	LONM_RAT	Lon protease homolog, mitochondrial	12752449	Changes in rat liver mitochondria with aging. Lon protease-like reactivity and N(epsilon)-carboxymethyllysine accumulation in the matrix.

Q76NU1	VATB_DICDI	V-type proton ATPase subunit B	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P70473	AMACR_RAT	Alpha-methylacyl-CoA racemase	8020470	Purification and properties of an alpha-methylacyl-CoA racemase from rat liver.

P41596	DOPR1_DROME	Dopamine receptor 1	18674913	D1 receptor activation in the mushroom bodies rescues sleep-loss- induced learning impairments in Drosophila.

Q54I79	ACTY_DICDI	Centractin	15496465	Formation of an actin-like filament concurrent with the enzymatic synthesis of inorganic polyphosphate.

O04905	UMPK_ARATH	Uridylate kinase	9576794	Cloning, expression in Escherichia coli, and characterization of Arabidopsis thaliana UMP/CMP kinase.

P54727	RD23B_HUMAN	UV excision repair protein RAD23 homolog B	8168482	Purification and cloning of a nucleotide excision repair complex involving the Xeroderma pigmentosum group C protein and a human homologue of yeast RAD23.

O88712	CTBP1_MOUSE	C-terminal-binding protein 1	18483224	Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex.

P38983	RSSA_RAT	40S ribosomal protein SA	8076763	Laminin receptor expression in rat intestine and liver during development and differentiation.

Q03267	IKZF1_MOUSE	DNA-binding protein Ikaros	18940586	Ikaros confers early temporal competence to mouse retinal progenitor cells.

P12887	UNG_YEAST	Uracil-DNA glycosylase, mitochondrial	2644266	Molecular cloning and primary structure of the uracil-DNA glycosylase gene from Saccharomyces cerevisiae.

Q9D154	ILEUA_MOUSE	Leukocyte elastase inhibitor A	12189154	Characterization of four murine homologs of the human ov-serpin monocyte neutrophil elastase inhibitor MNEI (SERPINB1).

Q9WTY2	REM2_RAT	GTP-binding protein REM 2	10727423	Rem2, a new member of the Rem/Rad/Gem/Kir family of Ras-related GTPases.

P24639	ANXA7_DICDI	Annexin A7	1824843	Identification of a homologue for annexin VII (synexin) in Dictyostelium discoideum.

P60510	PP4C_HUMAN	Serine/threonine-protein phosphatase 4 catalytic subunit	18715871	PP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4.

P34374	UNC36_CAEEL	Voltage-dependent calcium channel unc-36	8462849	The genetics of feeding in Caenorhabditis elegans.

P54840	GYS2_HUMAN	Glycogen [starch] synthase, liver	9691087	Mutations in the liver glycogen synthase gene in children with hypoglycemia due to glycogen storage disease type 0.

P38960	STN1_YEAST	Protein STN1	9042864	Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13.

Q99835	SMO_HUMAN	Smoothened homolog	9422511	Activating Smoothened mutations in sporadic basal-cell carcinoma.

Q9CAJ0	P2C16_ARATH	Protein phosphatase 2C 16	19624469	Modulation of drought resistance by the abscisic acid receptor PYL5 through inhibition of clade A PP2Cs.

Q8WY64	MYLIP_HUMAN	E3 ubiquitin-protein ligase MYLIP	14550572	Functional activities and cellular localization of the ezrin, radixin, moesin (ERM) and RING zinc finger domains in MIR.

O14305	SID1_SCHPO	Serine/threonine-protein kinase sid1	10775265	The role of the sid1p kinase and cdc14p in regulating the onset of cytokinesis in fission yeast.

Q00798	RBP1_PLAVB	Reticulocyte-binding protein 1	1617731	A reticulocyte-binding protein complex of Plasmodium vivax merozoites.

O59806	YJV8_SCHPO	Uncharacterized N-acetyltransferase C550.08	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P70605	KCNN3_RAT	Small conductance calcium-activated potassium channel protein 3	11245600	Cloning and functional expression of a liver isoform of the small conductance Ca2+-activated K+ channel SK3.

P30499	1C01_HUMAN	HLA class I histocompatibility antigen, Cw-1 alpha chain	1384166	The molecular basis for reactivity of anti-Cw1 and anti-Cw3 alloantisera with HLA-B46 haplotypes.

Q90ZE2	ZN703_DANRE	Zinc finger protein 703	14709556	Isolation of nlz2 and characterization of essential domains in Nlz family proteins.

Q9V4P1	ANLN_DROME	Actin-binding protein anillin	15496454	Anillin binds nonmuscle myosin II and regulates the contractile ring.

O94263	DPB2_SCHPO	DNA polymerase epsilon subunit B	15388803	Identification and cloning of two putative subunits of DNA polymerase epsilon in fission yeast.

P40096	NCB1_YEAST	Negative cofactor 2 complex subunit alpha	12237409	Direct stimulation of transcription by negative cofactor 2 (NC2) through TATA-binding protein (TBP).

Q5VZL5	ZMYM4_HUMAN	Zinc finger MYM-type protein 4	10486218	Cloning and mapping of members of the MYM family.

Q90ZL1	MSGN1_DANRE	Mesogenin-1	12684777	Characterization and expression of a presomitic mesoderm-specific mespo gene in zebrafish.

P16143	PO2F1_XENLA	POU domain, class 2, transcription factor 1	1732736	Sequential expression of multiple POU proteins during amphibian early development.

P32895	KPR1_YEAST	Ribose-phosphate pyrophosphokinase 1	14562095	Global analysis of protein localization in budding yeast.

P28737	MSP1_YEAST	Protein MSP1	8226973	Intramitochondrial protein sorting. Isolation and characterization of the yeast MSP1 gene which belongs to a novel family of putative ATPases.

Q16594	TAF9_HUMAN	Transcription initiation factor TFIID subunit 9	11564863	Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage- binding factors in vivo.

P25021	HRH2_HUMAN	Histamine H2 receptor	1714721	Molecular cloning of the human histamine H2 receptor.

Q04631	FNTA_RAT	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	1763049	Cloning and expression of a cDNA encoding the alpha subunit of rat p21ras protein farnesyltransferase.

P41250	SYG_HUMAN	Glycyl-tRNA synthetase	12690580	Glycyl tRNA synthetase mutations in Charcot-Marie-Tooth disease type 2D and distal spinal muscular atrophy type V.

Q61839	ANFC_MOUSE	C-type natriuretic peptide	7698765	Molecular cloning and chromosomal assignment of the mouse C-type natriuretic peptide (CNP) gene (Nppc): comparison with the human CNP gene (NPPC).

P32121	ARRB2_HUMAN	Beta-arrestin-2	16378096	Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling.

Q10173	NUF2_SCHPO	Kinetochore protein nuf2	15728720	Dissociation of the Nuf2-Ndc80 complex releases centromeres from the spindle-pole body during meiotic prophase in fission yeast.

P83949	UBX_DROME	Homeotic protein ultrabithorax	10067897	Structure of a DNA-bound Ultrabithorax-Extradenticle homeodomain complex.

Q5SXI5	ZN496_MOUSE	Zinc finger protein 496	17521633	Characterization of zinc finger protein 496 that interacts with Jumonji/JARID2.

P02511	CRYAB_HUMAN	Alpha-crystallin B chain	9731540	A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy.

Q10449	MU157_SCHPO	Meiotically up-regulated gene 157 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P32477	GSH1_YEAST	Glutamate--cysteine ligase	1687097	Molecular cloning of the gamma-glutamylcysteine synthetase gene of Saccharomyces cerevisiae.

Q9Y7S9	AMY3_SCHPO	Alpha-amylase 3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q80TQ2	CYLD_MOUSE	Ubiquitin carboxyl-terminal hydrolase CYLD	19893491	CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin.

O96759	ADAS_DICDI	Alkyldihydroxyacetonephosphate synthase	9837757	Nucleotide sequence of alkyl-dihydroxyacetonephosphate synthase cDNA from Dictyostelium discoideum.

Q03429	FMP36_YEAST	Protein FMP36, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

Q9NYB9	ABI2_HUMAN	Abl interactor 2	8649853	Identification of ArgBP1, an Arg protein tyrosine kinase binding protein that is the human homologue of a CNS-specific Xenopus gene.

P04694	ATTY_RAT	Tyrosine aminotransferase	2863382	Complete complementary DNA of rat tyrosine aminotransferase messenger RNA. Deduction of the primary structure of the enzyme.

Q794C0	VA0E1_RAT	V-type proton ATPase subunit e 1	11162653	Cloning of a D-serine-regulated transcript dsr-1 from the rat cerebral cortex.

Q04636	POB3_YEAST	FACT complex subunit POB3	16678108	The structure of the yFACT Pob3-M domain, its interaction with the DNA replication factor RPA, and a potential role in nucleosome deposition.

Q9NZH7	IL1F8_HUMAN	Interleukin-1 family member 8	10744718	Identification and initial characterization of four novel members of the interleukin-1 family.

Q95UN8	M3KSL_DROME	Mitogen-activated protein kinase kinase kinase	12676357	Drosophila mixed lineage kinase/slipper, a missing biochemical link in Drosophila JNK signaling.

O59790	ARK1_SCHPO	Serine/threonine-protein kinase ark1	12676091	S. pombe aurora kinase/survivin is required for chromosome condensation and the spindle checkpoint attachment response.

Q9H0U3	MAGT1_HUMAN	Magnesium transporter protein 1	12887896	Oligosaccharyltransferase isoforms that contain different catalytic STT3 subunits have distinct enzymatic properties.

P06208	LEU1_YEAST	2-isopropylmalate synthase	3275644	Yeast LEU4 encodes mitochondrial and nonmitochondrial forms of alpha- isopropylmalate synthase.

P38418	LOX2_ARATH	Lipoxygenase 2, chloroplastic	11161062	Molecular responses to aphid feeding in Arabidopsis in relation to plant defense pathways.

Q9Z2E2	MBD1_MOUSE	Methyl-CpG-binding domain protein 1	9774669	Identification and characterization of a family of mammalian methyl- CpG binding proteins.

O95947	TBX6_HUMAN	T-box transcription factor TBX6	9888994	Identification, mapping and phylogenomic analysis of four new human members of the T-box gene family: EOMES, TBX6, TBX18, and TBX19.

P05556	ITB1_HUMAN	Integrin beta-1	16754960	Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins.

O88713	KLRG1_MOUSE	Killer cell lectin-like receptor subfamily G member 1	9862665	Virus-activated CD8 T cells and lymphokine-activated NK cells express the mast cell function-associated antigen, an inhibitory C-type lectin.

Q9D9X8	SACA3_MOUSE	Sperm acrosome membrane-associated protein 3	15982649	Mouse SLLP1, a sperm lysozyme-like protein involved in sperm-egg binding and fertilization.

O14138	MIDA_SCHPO	Protein midA homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q13347	EIF3I_HUMAN	Eukaryotic translation initiation factor 3 subunit I	14688252	The j-subunit of human translation initiation factor eIF3 is required for the stable binding of eIF3 and its subcomplexes to 40 S ribosomal subunits in vitro.

O88177	PEX12_RAT	Peroxisome assembly protein 12	9632816	PEX12, the pathogenic gene of group III Zellweger syndrome: cDNA cloning by functional complementation on a CHO cell mutant, patient analysis, and characterization of PEX12p.

Q12906	ILF3_HUMAN	Interleukin enhancer-binding factor 3	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

P38633	MED31_YEAST	Mediator of RNA polymerase II transcription subunit 31	15356001	The Soh1/MED31 protein is an ancient component of Schizosaccharomyces pombe and Saccharomyces cerevisiae Mediator.

P53738	TR112_YEAST	Multifunctional methyltransferase subunit TRM112	14562095	Global analysis of protein localization in budding yeast.

Q9FE25	MYB75_ARATH	Transcription factor MYB75	15807784	Functional genomics by integrated analysis of metabolome and transcriptome of Arabidopsis plants over-expressing an MYB transcription factor.

Q925H4	KR167_MOUSE	Keratin-associated protein 16-7	17151017	Transcriptome and phenotypic analysis reveals Gata3-dependent signalling pathways in murine hair follicles.

Q9SA96	AROD1_ARATH	Arogenate dehydratase/prephenate dehydratase 1, chloroplastic	17726025	Phenylalanine biosynthesis in Arabidopsis thaliana. Identification and characterization of arogenate dehydratases.

Q8JHJ1	RL35_DANRE	60S ribosomal protein L35	15138505	Many ribosomal protein genes are cancer genes in zebrafish.

Q9FT73	RQL2_ARATH	ATP-dependent DNA helicase Q-like 2	18419780	AtRECQ2, a RecQ helicase homologue from Arabidopsis thaliana, is able to disrupt various recombinogenic DNA structures in vitro.

Q9FGI6	NDUS1_ARATH	NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q9HBM1	SPC25_HUMAN	Kinetochore protein Spc25	15961401	Architecture of the human Ndc80-Hec1 complex, a critical constituent of the outer kinetochore.

Q8WWQ8	STAB2_HUMAN	Stabilin-2	11829752	Stabilin-1 and -2 constitute a novel family of fasciclin-like hyaluronan receptor homologues.

Q04693	RSE1_YEAST	Pre-mRNA-splicing factor RSE1	10369685	Partial purification of the yeast U2 snRNP reveals a novel yeast pre- mRNA splicing factor required for pre-spliceosome assembly.

Q02732	CTF19_YEAST	Central kinetochore subunit CTF19	14633972	Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes.

Q9Z306	S22A4_MOUSE	Solute carrier family 22 member 4	11010964	Molecular and functional characterization of organic cation/carnitine transporter family in mice.

O43715	TRIA1_HUMAN	TP53-regulated inhibitor of apoptosis 1	15735003	p53CSV, a novel p53-inducible gene involved in the p53-dependent cell-survival pathway.

P10589	COT1_HUMAN	COUP transcription factor 1	2739739	COUP transcription factor is a member of the steroid receptor superfamily.

P40009	YND1_YEAST	Golgi apyrase	10409709	YND1, a homologue of GDA1, encodes membrane-bound apyrase required for Golgi N- and O-glycosylation in Saccharomyces cerevisiae.

Q7Z9I4	YCP6_SCHPO	Uncharacterized oxidoreductase C663.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q10286	ITR1_SCHPO	Myo-inositol transporter 1	9560432	Exogenous inositol and genes responsible for inositol transport are required for mating and sporulation in Shizosaccharomyces pombe.

Q7YXU4	CPNA_DICDI	Copine-A	16343335	Copine A, a calcium-dependent membrane-binding protein, transiently localizes to the plasma membrane and intracellular vacuoles in Dictyostelium.

O70444	PIM3_RAT	Serine/threonine-protein kinase pim-3	9632723	KID-1, a protein kinase induced by depolarization in brain.

Q8N726	CD2A2_HUMAN	Cyclin-dependent kinase inhibitor 2A, isoform 4	12581788	A novel putative collaborator of p19ARF.

P97460	NPAS2_MOUSE	Neuronal PAS domain-containing protein 2	12843397	Altered patterns of sleep and behavioral adaptability in NPAS2- deficient mice.

Q9JJC8	NIPA2_MOUSE	Magnesium transporter NIPA2	18667602	Functional characterization of NIPA2, a selective Mg2+ transporter.

Q9QX27	ST18_RAT	Suppression of tumorigenicity 18 protein	9478997	Isolation and characterization of a novel member of the neural zinc finger factor/myelin transcription factor family with transcriptional repression activity.

P31120	GLMM_ECOLI	Phosphoglucosamine mutase	10231382	Reaction mechanism of phosphoglucosamine mutase from Escherichia coli.

P01877	IGHA2_HUMAN	Ig alpha-2 chain C region	2241915	The structure and function of human IgA.

Q5B2G3	FAEC_EMENI	Feruloyl esterase C	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

P04147	PABP_YEAST	Polyadenylate-binding protein, cytoplasmic and nuclear	15630021	Yeast poly(A)-binding protein, Pab1, and PAN, a poly(A) nuclease complex recruited by Pab1, connect mRNA biogenesis to export.

Q02936	HH_DROME	Protein hedgehog	1340474	The Drosophila hedgehog gene is expressed specifically in posterior compartment cells and is a target of engrailed regulation.

Q9UER7	DAXX_HUMAN	Death domain-associated protein 6	12529400	Homeodomain-interacting protein kinase 1 modulates Daxx localization, phosphorylation, and transcriptional activity.

P05556	ITB1_HUMAN	Integrin beta-1	17925226	Rab25 associates with alpha5beta1 integrin to promote invasive migration in 3D microenvironments.

Q9US03	KLP2_SCHPO	Kinesin-like protein 2	16002618	The kinesin Klp2 mediates polarization of interphase microtubules in fission yeast.

P37172	ACVR1_MOUSE	Activin receptor type-1	15531373	BMP signaling through ACVRI is required for left-right patterning in the early mouse embryo.

Q03780	YD239_YEAST	Uncharacterized protein YDR239C	14562095	Global analysis of protein localization in budding yeast.

Q06405	ATPK_YEAST	ATP synthase subunit f, mitochondrial	9288937	The subunit f of mitochondrial yeast ATP synthase -- characterization of the protein and disruption of the structural gene ATP17.

Q12200	NPC1_YEAST	Niemann-Pick type C-related protein 1	14562095	Global analysis of protein localization in budding yeast.

P33552	CKS2_HUMAN	Cyclin-dependent kinases regulatory subunit 2	2227411	Human cDNAs encoding homologs of the small p34Cdc28/Cdc2-associated protein of Saccharomyces cerevisiae and Schizosaccharomyces pombe.

P0ABE9	CYNT_ECOLI	Carbonic anhydrase 1	1740425	Carbonic anhydrase in Escherichia coli. A product of the cyn operon.

Q9DBL9	ABHD5_MOUSE	1-acylglycerol-3-phosphate O-acyltransferase ABHD5	18606822	CGI-58, the causative gene for Chanarin-Dorfman syndrome, mediates acylation of lysophosphatidic acid.

Q12451	OSH2_YEAST	Oxysterol-binding protein homolog 2	11408574	Dual targeting of Osh1p, a yeast homologue of oxysterol-binding protein, to both the Golgi and the nucleus-vacuole junction.

P36649	CUEO_ECOLI	Blue copper oxidase cueO	11527384	CueO is a multi-copper oxidase that confers copper tolerance in Escherichia coli.

Q8IV48	ERI1_HUMAN	3'-5' exoribonuclease 1	16912046	Characterization of 3'hExo, a 3' exonuclease specifically interacting with the 3' end of histone mRNA.

P08337	MUTT_ECOLI	Mutator mutT protein	3288626	Studies on the mutator gene, mutT of Escherichia coli. Molecular cloning of the gene, purification of the gene product, and identification of a novel nucleoside triphosphatase.

P55771	PAX9_HUMAN	Paired box protein Pax-9	12657635	Human PLU-1 has transcriptional repression properties and interacts with the developmental transcription factors BF-1 and PAX9.

O94634	THDH_SCHPO	Threonine dehydratase, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P25090	FPR2_HUMAN	N-formyl peptide receptor 2	1374236	Isolation of a cDNA that encodes a novel granulocyte N-formyl peptide receptor.

Q02040	SF17A_HUMAN	Splicing factor, arginine/serine-rich 17A	16982639	XE7: a novel splicing factor that interacts with ASF/SF2 and ZNF265.

P01611	KV119_HUMAN	Ig kappa chain V-I region Wes	6778806	Preparative separation of the tryptic hydrolysate of a protein by high-pressure liquid chromatography. The primary structure of a monoclonal L-chain of k-type, subgroup I (Bence-Jones protein Wes).

O95229	ZWINT_HUMAN	ZW10 interactor	15485811	Human Zwint-1 specifies localization of Zeste White 10 to kinetochores and is essential for mitotic checkpoint signaling.

Q03554	GOT1_YEAST	Protein transport protein GOT1	10406798	Got1p and Sft2p: membrane proteins involved in traffic to the Golgi complex.

P25651	CSM1_YEAST	Monopolin complex subunit CSM1	11489916	A protein interaction map for cell polarity development.

P11802	CDK4_HUMAN	Cell division protein kinase 4	15558030	Characterization of VIK-1: a new Vav-interacting Kruppel-like protein.

P02994	EF1A_YEAST	Elongation factor 1-alpha	10766739	An aminoacylation-dependent nuclear tRNA export pathway in yeast.

O13024	INCEA_XENLA	Inner centromere protein A	17199039	Chromosomal enrichment and activation of the aurora B pathway are coupled to spatially regulate spindle assembly.

Q9URX0	YLX6_SCHPO	Uncharacterized oxidoreductase C922.06	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9VEG6	PERC_DROME	Chorion peroxidase	18216169	Drosophila Pxt: a cyclooxygenase-like facilitator of follicle maturation.

O14613	BORG1_HUMAN	Cdc42 effector protein 2	11035016	A new family of Cdc42 effector proteins, CEPs, function in fibroblast and epithelial cell shape changes.

Q15398	DLGP5_HUMAN	Disks large-associated protein 5	15145941	Fbx7 functions in the SCF complex regulating Cdk1-cyclin B- phosphorylated hepatoma up-regulated protein (HURP) proteolysis by a proline-rich region.

Q16555	DPYL2_HUMAN	Dihydropyrimidinase-related protein 2	16260607	CRMP-2 is involved in kinesin-1-dependent transport of the Sra- 1/WAVE1 complex and axon formation.

P20290	BTF3_HUMAN	Transcription factor BTF3	2320128	Sequencing and expression of complementary DNA for the general transcription factor BTF3.

P60061	ADIC_ECOLI	Arginine/agmatine antiporter	12867448	YjdE (AdiC) is the arginine:agmatine antiporter essential for arginine-dependent acid resistance in Escherichia coli.

P53152	MMS2_YEAST	Ubiquitin-conjugating enzyme variant MMS2	10089880	Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair.

Q9H8L6	MMRN2_HUMAN	Multimerin-2	11559704	Molecular cloning and characterization of EndoGlyx-1, an EMILIN-like multisubunit glycoprotein of vascular endothelium.

O75489	NDUS3_HUMAN	NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

Q9W420	SPT6H_DROME	Transcription elongation factor SPT6	12934007	Tracking FACT and the RNA polymerase II elongation complex through chromatin in vivo.

Q8WW52	F151A_HUMAN	Protein FAM151A	12975309	The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

P06276	CHLE_HUMAN	Cholinesterase	19452557	The structure of G117H mutant of butyrylcholinesterase: nerve agents scavenger.

Q62921	UB7I3_RAT	RanBP-type and C3HC4-type zinc finger-containing protein 1	9514928	Molecular cloning and characterization of a novel protein kinase C- interacting protein with structural motifs related to RBCC family proteins.

P83172	HCYC_CHEDE	Hemocyanin C chain	2620501	The relationship between N-terminal sequences and immunological characterization of crustacean hemocyanins.

Q08490	SGO1_YEAST	Shugoshin	14752166	A genome-wide screen identifies genes required for centromeric cohesion.

P54816	TBP7_CAEEL	Tat-binding homolog 7	17618463	The bromodomain protein LEX-1 acts with TAM-1 to modulate gene expression in C. elegans.

P39552	MST28_YEAST	Multicopy suppressor of SEC21 protein 28	12101299	Functional analysis of the Saccharomyces cerevisiae DUP240 multigene family reveals membrane-associated proteins that are not essential for cell viability.

Q99969	RARR2_HUMAN	Retinoic acid receptor responder protein 2	9204961	Tazarotene-induced gene 2 (TIG2), a novel retinoid-responsive gene in skin.

Q9UT07	UPS1_SCHPO	Protein ups1 homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q15303	ERBB4_HUMAN	Receptor tyrosine-protein kinase erbB-4	8383326	Ligand-specific activation of HER4/p180erbB4, a fourth member of the epidermal growth factor receptor family.

P30085	KCY_HUMAN	UMP-CMP kinase	10462544	Phosphorylation of deoxycytidine analog monophosphates by UMP-CMP kinase: molecular characterization of the human enzyme.

P27645	FCGR3_RAT	Low affinity immunoglobulin gamma Fc region receptor III	1692135	Characterization and expression of an Fc gamma receptor cDNA cloned from rat natural killer cells.

Q9UI38	TSP50_HUMAN	Probable threonine protease PRSS50	17283160	TSP50 encodes a testis-specific protease and is negatively regulated by p53.

O42699	RL19B_SCHPO	60S ribosomal protein L19-B	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P62517	OPGH_ECOLI	Glucans biosynthesis glucosyltransferase H	9352918	Topological analysis of the membrane-bound glucosyltransferase, MdoH, required for osmoregulated periplasmic glucan synthesis in Escherichia coli.

Q8TAC9	SCAM5_HUMAN	Secretory carrier-associated membrane protein 5	19240033	SCAMP5 links endoplasmic reticulum stress to the accumulation of expanded polyglutamine protein aggregates via endocytosis inhibition.

Q9W5E0	SUV42_DROME	Histone-lysine N-methyltransferase Suv4-20	15145825	A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin.

O13734	SGO2_SCHPO	Shugoshin-2	14972679	Two fission yeast homologs of Drosophila Mei-S332 are required for chromosome segregation during meiosis I and II.

O74844	FTA7_SCHPO	Kinetochore protein fta7	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P40427	EXD_DROME	Homeobox protein extradenticle	10067897	Structure of a DNA-bound Ultrabithorax-Extradenticle homeodomain complex.

P50990	TCPQ_HUMAN	T-complex protein 1 subunit theta	7890169	The eighth Cct gene, Cctq, encoding the theta subunit of the cytosolic chaperonin containing TCP-1.

Q8IN94	OSA_DROME	Trithorax group protein osa	10809665	The Drosophila brahma complex is an essential coactivator for the trithorax group protein zeste.

P20612	GNAT1_MOUSE	Guanine nucleotide-binding protein G(t) subunit alpha-1	2708360	Characterization of the mouse rod transducin alpha subunit gene.

P25591	VAC17_YEAST	vacuole-related protein 17	17699591	Atg18 regulates organelle morphology and Fab1 kinase activity independent of its membrane recruitment by phosphatidylinositol 3,5- bisphosphate.

P40157	VID27_YEAST	Vacuolar import and degradation protein 27	14562095	Global analysis of protein localization in budding yeast.

Q9HBX9	RXFP1_HUMAN	Relaxin receptor 1	12506116	H3 relaxin is a specific ligand for LGR7 and activates the receptor by interacting with both the ectodomain and the exoloop 2.

Q01984	HNMT_RAT	Histamine N-methyltransferase	1639806	Histamine N-methyltransferase from rat kidney. Cloning, nucleotide sequence, and expression in Escherichia coli cells.

Q13686	ALKB1_HUMAN	Alkylated DNA repair protein alkB homolog 1	18603530	Human AlkB homolog 1 is a mitochondrial protein that demethylates 3- methylcytosine in DNA and RNA.

Q9UN37	VPS4A_HUMAN	Vacuolar protein sorting-associated protein 4A	11563910	Mammalian cells express two VPS4 proteins both of which are involved in intracellular protein trafficking.

P24806	XTH24_ARATH	Xyloglucan endotransglucosylase/hydrolase protein 24	10406121	In vitro activities of four xyloglucan endotransglycosylases from Arabidopsis.

Q9R194	CRY2_MOUSE	Cryptochrome-2	17462724	Circadian mutant Overtime reveals F-box protein FBXL3 regulation of cryptochrome and period gene expression.

Q8TFF9	YP23_SCHPO	Putative amidase PB8B6.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P78330	SERB_HUMAN	Phosphoserine phosphatase	14673469	Mutations responsible for 3-phosphoserine phosphatase deficiency.

Q16658	FSCN1_HUMAN	Fascin	8068206	cDNA cloning and expression of the human homolog of the sea urchin fascin and Drosophila singed genes which encodes an actin-bundling protein.

O43824	GTPB6_HUMAN	Putative GTP-binding protein 6	9466997	A novel pseudoautosomal gene encoding a putative GTP-binding protein resides in the vicinity of the Xp/Yp telomere.

P78955	HUS1_SCHPO	Checkpoint protein hus1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q00653	NFKB2_HUMAN	Nuclear factor NF-kappa-B p100 subunit	1876189	Cloning of an NF-kappa B subunit which stimulates HIV transcription in synergy with p65.

O13967	BGS2_SCHPO	1,3-beta-glucan synthase component bgs2	11069657	bgs2+, a sporulation-specific glucan synthase homologue is required for proper ascospore wall maturation in fission yeast.

Q9M374	CRF6_ARATH	Ethylene-responsive transcription factor CRF6	16832061	A subset of Arabidopsis AP2 transcription factors mediates cytokinin responses in concert with a two-component pathway.

Q13586	STIM1_HUMAN	Stromal interaction molecule 1	16005298	STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx.

Q9SAR0	1A16_ARATH	1-aminocyclopropane-1-carboxylate synthase 6	10080689	A multi-responsive gene encoding 1-aminocyclopropane-1-carboxylate synthase (ACS6) in mature Arabidopsis leaves.

Q16629	SRSF7_HUMAN	Serine/arginine-rich splicing factor 7	15169763	Distinct sequence motifs within the 68-kDa subunit of cleavage factor Im mediate RNA binding, protein-protein interactions, and subcellular localization.

O94740	CDC37_SCHPO	Hsp90 co-chaperone Cdc37	12861001	Identification of cdc37 as a novel regulator of the stress-responsive mitogen-activated protein kinase.

Q99JZ7	ERRFI_MOUSE	ERBB receptor feedback inhibitor 1	19710174	Mig-6 is required for appropriate lung development and to ensure normal adult lung homeostasis.

Q9S7B5	THRC1_ARATH	Threonine synthase 1, chloroplastic	16319072	Allosteric threonine synthase. Reorganization of the pyridoxal phosphate site upon asymmetric activation through S-adenosylmethionine binding to a novel site.

Q03012	SPP1_YEAST	COMPASS component SPP1	11742990	The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4.

Q10225	BTB3_SCHPO	BTB/POZ domain-containing protein 3	14527422	BTB/POZ domain proteins are putative substrate adaptors for cullin 3 ubiquitin ligases.

P39723	SPC72_YEAST	Spindle pole component SPC72	9606209	The yeast spindle pole body component Spc72p interacts with Stu2p and is required for proper microtubule assembly.

Q9M424	NXS_SOLTU	Neoxanthin synthase, chloroplastic	11094161	Identification of a novel gene coding for neoxanthin synthase from Solanum tuberosum.

Q9QYW0	AATF_RAT	Protein AATF	10580117	AATF -- a novel transcription factor that interacts with Dlk/ZIP kinase and interferes with apoptosis.

P14404	EVI1_MOUSE	MDS1 and EVI1 complex locus protein EVI1	19767769	Pbx1 is a downstream target of Evi-1 in hematopoietic stem/progenitors and leukemic cells.

Q921C3	BRWD1_MOUSE	Bromodomain and WD repeat-containing protein 1	12889071	Expression of the Wdr9 gene and protein products during mouse development.

P38054	CUSA_ECOLI	Cation efflux system protein cusA	12813074	Molecular analysis of the copper-transporting efflux system CusCFBA of Escherichia coli.

Q94131	PIE1_CAEEL	Pharynx and intestine in excess protein 1	8751440	The PIE-1 protein and germline specification in C. elegans embryos.

P30051	TEAD1_MOUSE	Transcriptional enhancer factor TEF-1	7958896	Transcriptional enhancer factor 1 disruption by a retroviral gene trap leads to heart defects and embryonic lethality in mice.

P32896	PDC2_YEAST	Protein PDC2	8264540	Characterisation of PDC2, a gene necessary for high level expression of pyruvate decarboxylase structural genes in Saccharomyces cerevisiae.

Q9H2V7	SPNS1_HUMAN	Protein spinster homolog 1	12815463	HSpin1, a transmembrane protein interacting with Bcl-2/Bcl-xL, induces a caspase-independent autophagic cell death.

Q07589	YD144_YEAST	Uncharacterized protein YDL144C	14562095	Global analysis of protein localization in budding yeast.

P38861	NMD3_YEAST	60S ribosomal export protein NMD3	11086007	Nmd3p is a Crm1p-dependent adapter protein for nuclear export of the large ribosomal subunit.

Q8WTW4	NPRL2_HUMAN	Nitrogen permease regulator 2-like protein	18616680	TUSC4/NPRL2, a novel PDK1-interacting protein, inhibits PDK1 tyrosine phosphorylation and its downstream signaling.

P46413	GSHB_RAT	Glutathione synthetase	7862666	Amino acid sequence of rat kidney glutathione synthetase.

Q9Z1M9	SMC1A_RAT	Structural maintenance of chromosomes protein 1A	10652260	Association of mammalian SMC1 and SMC3 proteins with meiotic chromosomes and synaptonemal complexes.

Q3MKQ2	BEX1_RAT	Protein BEX1	15958283	Characterization of the Bex gene family in humans, mice, and rats.

Q9HCQ7	RFRP_HUMAN	FMRFamide-related peptides	11025660	New neuropeptides containing carboxy-terminal RFamide and their receptor in mammals.

P0ADX9	RSMD_ECOLI	Ribosomal RNA small subunit methyltransferase D	17189261	Methyltransferase that modifies guanine 966 of the 16 S rRNA: functional identification and tertiary structure.

Q12078	SMF3_YEAST	Iron transporter SMF3	11027260	Saccharomyces cerevisiae expresses three functionally distinct homologues of the nramp family of metal transporters.

Q08605	GAGA_DROME	Transcription factor GAGA	12601174	Genomewide analysis of Drosophila GAGA factor target genes reveals context-dependent DNA binding.

O14033	YEMC_SCHPO	Uncharacterized protein C29B12.12	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9BZX4	ROP1B_HUMAN	Ropporin-1B	11278869	Identification of sperm-specific proteins that interact with A-kinase anchoring proteins in a manner similar to the type II regulatory subunit of PKA.

Q06203	PUR1_HUMAN	Amidophosphoribosyltransferase	8106516	Two genes for de novo purine nucleotide synthesis on human chromosome 4 are closely linked and divergently transcribed.

Q55E54	COROB_DICDI	Coronin-B	20071332	A Coronin7 homolog with functions in actin-driven processes.

Q9WU39	SCNNG_MOUSE	Amiloride-sensitive sodium channel subunit gamma	10409305	Cloning and functional expression of the mouse epithelial sodium channel.

Q09470	KCNA1_HUMAN	Potassium voltage-gated channel subfamily A member 1	7842011	Episodic ataxia/myokymia syndrome is associated with point mutations in the human potassium channel gene, KCNA1.

P33450	FAT_DROME	Cadherin-related tumor suppressor	1959133	The fat tumor suppressor gene in Drosophila encodes a novel member of the cadherin gene superfamily.

Q13404	UB2V1_HUMAN	Ubiquitin-conjugating enzyme E2 variant 1	9418904	Role of UEV-1, an inactive variant of the E2 ubiquitin-conjugating enzymes, in in vitro differentiation and cell cycle behavior of HT-29- M6 intestinal mucosecretory cells.

P0AAN9	IRAP_ECOLI	Anti-adapter protein iraP	16600914	Modulating RssB activity: IraP, a novel regulator of sigma(S) stability in Escherichia coli.

P27584	GPA1_SCHPO	Guanine nucleotide-binding protein alpha-1 subunit	1905818	Isolation and characterization of a gene encoding a G-protein alpha subunit from Schizosaccharomyces pombe: involvement in mating and sporulation pathways.

Q9NZM6	PK2L2_HUMAN	Polycystic kidney disease 2-like 2 protein	10602361	Genes homologous to the autosomal dominant polycystic kidney disease genes (PKD1 and PKD2).

P40017	YAT2_YEAST	Carnitine O-acetyltransferase YAT2	11329169	Carnitine-dependent metabolic activities in Saccharomyces cerevisiae: three carnitine acetyltransferases are essential in a carnitine- dependent strain.

Q9P6M3	MIS14_SCHPO	Kinetochore protein mis14	16079914	Molecular analysis of kinetochore architecture in fission yeast.

O22476	BRI1_ARATH	Protein BRASSINOSTEROID INSENSITIVE 1	10938344	BRASSINOSTEROID-INSENSITIVE-1 is a ubiquitously expressed leucine- rich repeat receptor serine/threonine kinase.

O74903	YCS3_SCHPO	Uncharacterized calcium-binding protein C613.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q06704	IMH1_YEAST	Golgin IMH1	9880327	Structural and functional analysis of a novel coiled-coil protein involved in Ypt6 GTPase-regulated protein transport in yeast.

P23469	PTPRE_HUMAN	Receptor-type tyrosine-protein phosphatase epsilon	10980613	Generation of novel cytoplasmic forms of protein tyrosine phosphatase epsilon by proteolytic processing and translational control.

Q6K1E7	GGNB1_MOUSE	Gametogenetin-binding protein 1	15642376	Yeast two-hybrid screens imply that GGNBP1, GGNBP2 and OAZ3 are potential interaction partners of testicular germ cell-specific protein GGN1.

Q9WUL5	PD1L2_MOUSE	Programmed cell death 1 ligand 2	11224527	PD-L2 is a second ligand for PD-1 and inhibits T cell activation.

Q08605	GAGA_DROME	Transcription factor GAGA	9241251	Multiple isoforms of GAGA factor, a critical component of chromatin structure.

Q04491	SEC13_YEAST	Protein transport protein SEC13	11823431	Modular self-assembly of a Y-shaped multiprotein complex from seven nucleoporins.

O94655	YPT7_SCHPO	GTP-binding protein ypt7	9443913	Regulated vacuole fusion and fission in Schizosaccharomyces pombe: an osmotic response dependent on MAP kinases.

Q38819	CCA23_ARATH	Cyclin-A2-3	16415207	The A-type cyclin CYCA2;3 is a key regulator of ploidy levels in Arabidopsis endoreduplication.

Q3C1E9	ASF1_CHICK	Histone chaperone ASF1	16537536	Asf1 is required for viability and chromatin assembly during DNA replication in vertebrate cells.

O60928	IRK13_HUMAN	Inward rectifier potassium channel 13	9738472	Cloning and characterization of a novel human inwardly rectifying potassium channel predominantly expressed in small intestine.

Q8C031	LRC4C_MOUSE	Leucine-rich repeat-containing protein 4C	15590698	Myosin XVa and whirlin, two deafness gene products required for hair bundle growth, are located at the stereocilia tips and interact directly.

P17267	IF_RAT	Gastric intrinsic factor	3422425	Isolation and structural characterization of a cDNA clone encoding rat gastric intrinsic factor.

Q9CPR5	RM15_MOUSE	39S ribosomal protein L15, mitochondrial	14651853	Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.

Q9BQY9	DBND2_HUMAN	Dysbindin domain-containing protein 2	16618118	Dysbindin structural homologue CK1BP is an isoform-selective binding partner of human casein kinase-1.

Q9Z139	ROR1_MOUSE	Tyrosine-protein kinase transmembrane receptor ROR1	10231392	Spatio-temporally regulated expression of receptor tyrosine kinases, mRor1, mRor2, during mouse development: implications in development and function of the nervous system.

Q9JIY2	HAKAI_MOUSE	E3 ubiquitin-protein ligase Hakai	11836526	Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex.

P59222	SREC2_MOUSE	Scavenger receptor class F member 2	12154095	SREC-II, a new member of the scavenger receptor type F family, trans- interacts with SREC-I through its extracellular domain.

P05937	CALB1_HUMAN	Calbindin	3691519	Human 27-kDa calbindin complementary DNA sequence. Evolutionary and functional implications.

P89105	CTR9_YEAST	RNA polymerase-associated protein CTR9	11058104	The yeast CDP1 gene encodes a triple-helical DNA-binding protein.

Q9USY2	YOW4_SCHPO	Uncharacterized RNA-binding protein C1861.04c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O23138	CYC2_ARATH	Probable cytochrome c At1g22840	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q9H6D7	HAUS4_HUMAN	HAUS augmin-like complex subunit 4	19369198	The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells.

Q9PTP2	AXNR_XENLA	Axin-related protein	10688669	Interaction of dishevelled and Xenopus axin-related protein is required for wnt signal transduction.

P11230	ACHB_HUMAN	Acetylcholine receptor subunit beta	8651643	A beta-subunit mutation in the acetylcholine receptor channel gate causes severe slow-channel syndrome.

P48552	NRIP1_HUMAN	Nuclear receptor-interacting protein 1	11266503	Regulation of glucocorticoid receptor activity by 14-3-3-dependent intracellular relocalization of the corepressor RIP140.

O65375	LRX1_ARATH	Leucine-rich repeat extensin-like protein 1	11331608	The chimeric leucine-rich repeat/extensin cell wall protein LRX1 is required for root hair morphogenesis in Arabidopsis thaliana.

Q9URX1	YLX5_SCHPO	UNC93-like protein C922.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O74855	YQ95_SCHPO	Uncharacterized WD repeat-containing protein C18.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

A0T2N3	APJB_DANRE	Apelin receptor B	17336905	Apelin and its receptor control heart field formation during zebrafish gastrulation.

Q50L42	PA24E_MOUSE	Cytosolic phospholipase A2 epsilon	15866882	Identification of novel cytosolic phospholipase A(2)s, murine cPLA(2)delta, epsilon, and zeta, which form a gene cluster with cPLA(2)beta.

Q9JJW5	MYOZ2_MOUSE	Myozenin-2	11114196	Calsarcins, a novel family of sarcomeric calcineurin-binding proteins.

Q8TEE9	SAP25_HUMAN	Histone deacetylase complex subunit SAP25	16449650	Identification and characterization of SAP25, a novel component of the mSin3 corepressor complex.

Q39102	FTSH1_ARATH	ATP-dependent zinc metalloprotease FTSH 1, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q24185	HOOK_DROME	Protein hook	11018772	Drosophila endosomal proteins hook and deep orange regulate synapse size but not synaptic vesicle recycling.

P48439	OST3_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3	9405463	The highly conserved Stt3 protein is a subunit of the yeast oligosaccharyltransferase and forms a subcomplex with Ost3p and Ost4p.

Q9FMD9	GLN14_ARATH	Glutamine synthetase cytosolic isozyme 1-4	16338958	Gln49 and Ser174 residues play critical roles in determining the catalytic efficiencies of plant glutamine synthetase.

P01160	ANF_HUMAN	Atrial natriuretic factor	6230082	Purification and complete amino acid sequence of alpha-human atrial natriuretic polypeptide (alpha-hANP).

P56597	NDK5_HUMAN	Nucleoside diphosphate kinase homolog 5	9742940	A new human nm23 homologue (nm23-H5) specifically expressed in testis germinal cells.

Q9M8U1	CML18_ARATH	Probable calcium-binding protein CML18	16249341	Vacuolar Na(+)/H(+) antiporter cation selectivity is regulated by calmodulin from within the vacuole in a Ca2(+)- and pH-dependent manner.

P32558	SPT16_YEAST	FACT complex subunit SPT16	12242279	RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach.

Q9H9C1	VIPAR_HUMAN	VPS33B-interacting protein	19109425	SPE-39 family proteins interact with the HOPS complex and function in lysosomal delivery.

P27987	IP3KB_HUMAN	Inositol-trisphosphate 3-kinase B	1654894	Molecular cloning and expression of a new putative inositol 1,4,5- trisphosphate 3-kinase isoenzyme.

Q80TR4	SLIT1_MOUSE	Slit homolog 1 protein	10433822	The mouse SLIT family: secreted ligands for ROBO expressed in patterns that suggest a role in morphogenesis and axon guidance.

Q8I7P9	POL5_DROME	Retrovirus-related Pol polyprotein from transposon opus	12537573	The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

Q02969	PEX25_YEAST	Peroxisomal membrane protein PEX25	12135984	Transcriptome profiling to identify genes involved in peroxisome assembly and function.

Q9FKT3	UBC30_ARATH	Ubiquitin-conjugating enzyme E2 30	16339806	Genome analysis and functional characterization of the E2 and RING- type E3 ligase ubiquitination enzymes of Arabidopsis.

Q10322	DMA1_SCHPO	Probable E3 ubiquitin-protein ligase dma1	12479804	Dma1 prevents mitotic exit and cytokinesis by inhibiting the septation initiation network (SIN).

O59714	YBH6_SCHPO	Uncharacterized membrane protein C3B8.06	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NYW7	TA2R1_HUMAN	Taste receptor type 2 member 1	10761934	A novel family of mammalian taste receptors.

P20050	HOP1_YEAST	Meiosis-specific protein HOP1	2107981	The HOP1 gene encodes a meiosis-specific component of yeast chromosomes.

Q9P1W9	PIM2_HUMAN	Serine/threonine-protein kinase pim-2	16548883	Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection.

P38273	CCZ1_YEAST	Vacuolar fusion protein CCZ1	12208507	Ccz1p/Aut11p/Cvt16p is essential for autophagy and the cvt pathway.

Q8LL17	SON1_ARATH	Protein SUPPRESSOR OF NIM1 1	12119368	Arabidopsis SON1 is an F-box protein that regulates a novel induced defense response independent of both salicylic acid and systemic acquired resistance.

Q9P6R0	TF3B_SCHPO	Transcription factor IIIB 60 kDa subunit	12682361	The fission yeast TFIIB-related factor limits RNA polymerase III to a TATA-dependent pathway of TBP recruitment.

P80748	LV302_HUMAN	Ig lambda chain V-III region LOI	10510403	Nephritogenic lambda light chain dimer: a unique human miniautoantibody against complement factor H.

P51811	XK_HUMAN	Membrane transport protein XK	8004674	Isolation of the gene for McLeod syndrome that encodes a novel membrane transport protein.

O88509	DNM3B_MOUSE	DNA (cytosine-5)-methyltransferase 3B	18814855	Dynamic transition of Dnmt3b expression in mouse pre- and early post- implantation embryos.

P13609	SRGN_MOUSE	Serglycin	17010166	A role for serglycin proteoglycan in granular retention and processing of mast cell secretory granule components.

A4ZDL6	GNK2_GINBI	Antifungal protein ginkbilobin-2	17338634	Purification, characterization, and molecular gene cloning of an antifungal protein from Ginkgo biloba seeds.

B5LUQ3	FALX2_LITFA	Preprofallaxidin-2	18803332	The fallaxidin peptides from the skin secretion of the eastern dwarf tree frog Litoria fallax. Sequence determination by positive and negative ion electrospray mass spectrometry: antimicrobial activity and cDNA cloning of the fallaxidins.

Q9LUW0	LOX5_ARATH	Lipoxygenase 5, chloroplastic	17369372	Oxylipins produced by the 9-lipoxygenase pathway in Arabidopsis regulate lateral root development and defense responses through a specific signaling cascade.

P02751	FINC_HUMAN	Fibronectin	10075919	Crystal structure of a heparin- and integrin-binding segment of human fibronectin.

O73689	ZIC1_XENLA	Zinc finger protein ZIC 1	16892174	The zic1 gene is an activator of Wnt signaling.

P30559	OXYR_HUMAN	Oxytocin receptor	1313946	Structure and expression of a human oxytocin receptor.

O95786	DDX58_HUMAN	Probable ATP-dependent RNA helicase DDX58	18724357	STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling.

Q94887	NRX4_DROME	Neurexin-4	15459097	Drosophila contactin, a homolog of vertebrate contactin, is required for septate junction organization and paracellular barrier function.

Q8VEE1	LMCD1_MOUSE	LIM and cysteine-rich domains protein 1	16199866	LMCD1/Dyxin is a novel transcriptional cofactor that restricts GATA6 function by inhibiting DNA binding.

Q63553	SNRK_RAT	SNF-related serine/threonine-protein kinase	10930554	SNRK, a member of the SNF1 family, is related to low K(+)-induced apoptosis of cultured rat cerebellar granule neurons.

Q9C5V6	TOP6B_ARATH	DNA topoisomerase 6 subunit B	12119417	A crucial role for the putative Arabidopsis topoisomerase VI in plant growth and development.

Q9VYB0	BTHD_DROME	Selenoprotein BthD	11389138	Selenium metabolism in Drosophila: selenoproteins, selenoprotein mRNA expression, fertility, and mortality.

Q9HEQ9	TCG1_SCHPO	Single-stranded TG1-3 DNA-binding protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q14943	KI3S1_HUMAN	Killer cell immunoglobulin-like receptor 3DS1	8662091	Alternatively spliced forms of human killer inhibitory receptors.

P76010	YCGR_ECOLI	Flagellar brake protein YcgR	11031114	Two novel flagellar components and H-NS are involved in the motor function of Escherichia coli.

O75882	ATRN_HUMAN	Attractin	17261078	Does human attractin have DP4 activity?

Q08492	BUD21_YEAST	Bud site selection protein 21	12068309	A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis.

P01225	FSHB_HUMAN	Follitropin subunit beta	8220432	Primary amenorrhoea and infertility due to a mutation in the beta- subunit of follicle-stimulating hormone.

Q800Y2	MGP_ARGRE	Matrix Gla protein	12568402	Purification of matrix Gla protein from a marine teleost fish, Argyrosomus regius: calcified cartilage and not bone as the primary site of MGP accumulation in fish.

Q9UKT8	FBXW2_HUMAN	F-box/WD repeat-containing protein 2	10531035	Identification of a family of human F-box proteins.

P81447	GLCM1_CAPHI	Glycosylation-dependent cell adhesion molecule 1	9749374	The primary structure of caprine PP3: amino acid sequence, phosphorylation, and glycosylation of component PP3 from the proteose- peptone fraction of caprine milk.

Q9XUN9	TNNI3_CAEEL	Troponin I 3	15743415	Tissue expression of four troponin I genes and their molecular interactions with two troponin C isoforms in Caenorhabditis elegans.

O08967	CYH3_MOUSE	Cytohesin-3	10605025	Anergic T lymphocytes selectively express an integrin regulatory protein of the cytohesin family.

P43680	SOX18_MOUSE	Transcription factor SOX-18	7651823	Trans-activation and DNA-binding properties of the transcription factor, Sox-18.

Q9NZA1	CLIC5_HUMAN	Chloride intracellular channel protein 5	10793131	Identification of a novel member of the chloride intracellular channel gene family (CLIC5) that associates with the actin cytoskeleton of placental microvilli.

O59744	YN28_SCHPO	Uncharacterized transcriptional regulatory protein C530.08	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q13049	TRI32_HUMAN	E3 ubiquitin-protein ligase TRIM32	7778269	Identification of a novel human zinc finger protein that specifically interacts with the activation domain of lentiviral Tat proteins.

Q4VYR7	FOXP4_XENLA	Forkhead box protein P4	16609867	The FoxP subclass in Xenopus laevis development.

Q07657	SHS1_YEAST	Seventh homolog of septin 1	9790978	Shs1p: a novel member of septin that interacts with spa2p, involved in polarized growth in Saccharomyces cerevisiae.

Q61839	ANFC_MOUSE	C-type natriuretic peptide	11259675	Dwarfism and early death in mice lacking C-type natriuretic peptide.

O94543	YCD3_SCHPO	Uncharacterized membrane protein C1322.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O94514	NOP56_SCHPO	Nucleolar protein 56	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P31673	HS174_ORYSJ	17.4 kDa class I heat shock protein	19703271	Rice sHsp genes: genomic organization and expression profiling under stress and development.

Q6P1K2	PMF1_HUMAN	Polyamine-modulated factor 1	16585270	The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation.

O02298	GCY35_CAEEL	Soluble guanylate cyclase gcy-35	15220933	Oxygen sensation and social feeding mediated by a C. elegans guanylate cyclase homologue.

Q9FVC1	SVP_ARATH	MADS-box protein SVP	16679456	AGL24, SHORT VEGETATIVE PHASE, and APETALA1 redundantly control AGAMOUS during early stages of flower development in Arabidopsis.

Q91VD1	LEG12_MOUSE	Galectin-12	11435439	Galectin-12, an adipose-expressed galectin-like molecule possessing apoptosis-inducing activity.

Q8TDS5	OXER1_HUMAN	Oxoeicosanoid receptor 1	12065583	Identification of a novel human eicosanoid receptor coupled to G(i/o).

P09838	TDT_MOUSE	DNA nucleotidylexotransferase	8464703	Differential splicing in mouse thymus generates two forms of terminal deoxynucleotidyl transferase.

Q9D2G5	SYNJ2_MOUSE	Synaptojanin-2	9636665	Molecular cloning of multiple isoforms of synaptojanin 2 and assignment of the gene to mouse chromosome 17A2-3.1.

Q94502	GANAB_DICDI	Neutral alpha-glucosidase AB	9397534	Consequences of disrupting the gene that encodes alpha-glucosidase II in the N-linked oligosaccharide biosynthesis pathway of Dictyostelium discoideum.

Q9P6P3	PPK15_SCHPO	Serine/threonine-protein kinase ppk15	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P62859	RS28_RAT	40S ribosomal protein S28	1679328	The primary structure of rat ribosomal protein S28.

O93507	TAL1_DANRE	T-cell acute lymphocytic leukemia protein 1 homolog	16210319	Distinct roles for SCL in erythroid specification and maturation in zebrafish.

P59528	TR123_MOUSE	Taste receptor type 2 member 123	11854532	Expression of bitter taste receptors of the T2R family in the gastrointestinal tract and enteroendocrine STC-1 cells.

O74627	CG1C_SCHPO	Cyclin pch1	12475973	Interactions between fission yeast Cdk9, its cyclin partner Pch1, and mRNA capping enzyme Pct1 suggest an elongation checkpoint for mRNA quality control.

Q03834	MSH6_YEAST	DNA mismatch repair protein MSH6	9819445	Saccharomyces cerevisiae Msh2p and Msh6p ATPase activities are both required during mismatch repair.

Q9VIP7	ACASE_DROME	Alkaline ceramidase	10623899	Central brain postembryonic development in Drosophila: implication of genes expressed at the interhemispheric junction.

A1ZAJ2	KIF1A_DROME	Kinesin-like protein unc-104	17643120	A Drosophila kinesin required for synaptic bouton formation and synaptic vesicle transport.

Q84WU8	FTSH3_ARATH	ATP-dependent zinc metalloprotease FTSH 3, mitochondrial	14630971	Coordinated regulation and complex formation of yellow variegated1 and yellow variegated2, chloroplastic FtsH metalloproteases involved in the repair cycle of photosystem II in Arabidopsis thylakoid membranes.

O14672	ADA10_HUMAN	Disintegrin and metalloproteinase domain-containing protein 10	8694785	Molecular cloning of MADM: a catalytically active mammalian disintegrin-metalloprotease expressed in various cell types.

Q9Y255	PRLD1_HUMAN	PRELI domain-containing protein 1, mitochondrial	10784606	PRELI, the human homologue of the avian px19, is expressed by germinal center B lymphocytes.

P56942	MCH_MOUSE	Pro-MCH	8724342	Developmental and stage-dependent expression of melanin-concentrating hormone in mammalian germ cells.

P35237	SPB6_HUMAN	Serpin B6	8415716	Cloning and molecular characterization of a human intracellular serine proteinase inhibitor.

Q12056	ISU2_YEAST	Iron sulfur cluster assembly protein 2, mitochondrial	10588895	Saccharomyces cerevisiae ISU1 and ISU2: members of a well-conserved gene family for iron-sulfur cluster assembly.

O35295	PURB_MOUSE	Transcriptional activator protein Pur-beta	9334258	Sequence of cDNAs encoding components of vascular actin single- stranded DNA-binding factor 2 establish identity to Puralpha and Purbeta.

O15118	NPC1_HUMAN	Niemann-Pick C1 protein	9927649	Niemann-Pick C1 protein: obligatory roles for N-terminal domains and lysosomal targeting in cholesterol mobilization.

Q969H4	CNKR1_HUMAN	Connector enhancer of kinase suppressor of ras 1	14749388	Human CNK1 acts as a scaffold protein, linking Rho and Ras signal transduction pathways.

Q38998	AKT1_ARATH	Potassium channel AKT1	17898163	A protein phosphorylation/dephosphorylation network regulates a plant potassium channel.

P16140	VATB_YEAST	V-type proton ATPase subunit B	11283612	Skp1 forms multiple protein complexes, including RAVE, a regulator of V-ATPase assembly.

Q8R2H7	TRAK2_RAT	Trafficking kinesin-binding protein 2	12034717	Identification, molecular cloning, and characterization of a novel GABAA receptor-associated protein, GRIF-1.

P51659	DHB4_HUMAN	Peroxisomal multifunctional enzyme type 2	8902629	Purification and properties of human D-3-hydroxyacyl-CoA dehydratase: medium-chain enoyl-CoA hydratase is D-3-hydroxyacyl-CoA dehydratase.

P49842	STK19_HUMAN	Serine/threonine-protein kinase 19	9812991	The G11 gene located in the major histocompatibility complex encodes a novel nuclear serine/threonine protein kinase.

O43148	MCES_HUMAN	mRNA cap guanine-N7 methyltransferase	9790902	Cloning and characterization of three human cDNAs encoding mRNA (guanine-7-)methyltransferase, an mRNA cap methylase.

P11928	OAS1A_MOUSE	2'-5'-oligoadenylate synthase 1A	2171206	A full-length murine 2-5A synthetase cDNA transfected in NIH-3T3 cells impairs EMCV but not VSV replication.

P11458	NADA_ECOLI	Quinolinate synthase A	15967443	Quinolinate synthetase, an iron-sulfur enzyme in NAD biosynthesis.

O82662	SUCB_ARATH	Succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P56732	AVR2_CHICK	Avidin-related protein 2	16212654	Avidin related protein 2 shows unique structural and functional features among the avidin protein family.

P58012	FOXL2_HUMAN	Forkhead box protein L2	12149404	Identification of novel mutations in FOXL2 associated with premature ovarian failure.

P13393	TBP_YEAST	TATA-box-binding protein	2677740	Cloning and structure of a yeast gene encoding a general transcription initiation factor TFIID that binds to the TATA box.

Q9Y223	GLCNE_HUMAN	Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase	10330343	Mutations in the human UDP-N-acetylglucosamine 2-epimerase gene define the disease sialuria and the allosteric site of the enzyme.

P79005	TAZ1_SCHPO	Telomere length regulator taz1	11270572	Schizosaccharomyces pombe taf1+ is required for nitrogen starvation- induced sexual development and for entering the dormant GO state.

Q9UKV0	HDAC9_HUMAN	Histone deacetylase 9	20188095	Protein kinase C-related kinase targets nuclear localization signals in a subset of class IIa histone deacetylases.

P32929	CGL_HUMAN	Cystathionine gamma-lyase	1339280	Cloning and nucleotide sequence of human liver cDNA encoding for cystathionine gamma-lyase.

O49482	CADH5_ARATH	Cinnamyl alcohol dehydrogenase 5	14745009	Functional reclassification of the putative cinnamyl alcohol dehydrogenase multigene family in Arabidopsis.

P41838	RAE1_SCHPO	Poly(A)+ RNA export protein	7706287	A mutation in the Schizosaccharomyces pombe rae1 gene causes defects in poly(A)+ RNA export and in the cytoskeleton.

P18064	GPA1_ARATH	Guanine nucleotide-binding protein alpha-1 subunit	12837948	The Arabidopsis cupin domain protein AtPirin1 interacts with the G protein alpha-subunit GPA1 and regulates seed germination and early seedling development.

P58463	FOXP2_MOUSE	Forkhead box protein P2	11358962	Characterization of a new subfamily of winged-helix/forkhead (Fox) genes that are expressed in the lung and act as transcriptional repressors.

P0C186	PNTAA_RHORU	NAD(P) transhydrogenase subunit alpha part 1	7844118	Energy-transducing nicotinamide nucleotide transhydrogenase: nucleotide sequences of the genes and predicted amino acid sequences of the subunits of the enzyme from Rhodospirillum rubrum.

Q6UUV9	CRTC1_HUMAN	CREB-regulated transcription coactivator 1	14536081	TORCs: transducers of regulated CREB activity.

P15374	UCHL3_HUMAN	Ubiquitin carboxyl-terminal hydrolase isozyme L3	19154770	Ubiquitin dimers control the hydrolase activity of UCH-L3.

P26717	NKG2C_HUMAN	NKG2-C type II integral membrane protein	9683661	The genomic organization of NKG2C, E, F, and D receptor genes in the human natural killer gene complex.

O09114	PTGDS_MOUSE	Prostaglandin-H2 D-isomerase	8922532	Developmental expression of murine Beta-trace in embryos and adult animals suggests a function in maturation and maintenance of blood- tissue barriers.

P21856	GDIA_BOVIN	Rab GDP dissociation inhibitor alpha	2115118	Molecular cloning and characterization of a novel type of regulatory protein (GDI) for smg p25A, a ras p21-like GTP-binding protein.

Q8NET6	CHSTD_HUMAN	Carbohydrate sulfotransferase 13	12080076	Molecular cloning and characterization of chondroitin-4-O- sulfotransferase-3. A novel member of the HNK-1 family of sulfotransferases.

O43402	CX4NB_HUMAN	Neighbor of COX4	10337626	The 5-prime region of the COX4 gene contains a novel overlapping gene, NOC4.

Q8N653	LZTR1_HUMAN	Leucine-zipper-like transcriptional regulator 1	7633402	Isolation and characterization of a novel gene deleted in DiGeorge syndrome.

P83129	SODC_PAROL	Superoxide dismutase [Cu-Zn]	11290457	Purification, N-terminal amino acid sequence, and some properties of Cu,Zn-superoxide dismutase from Japanese flounder (Paralichthys olivaceus) hepato-pancreas.

P43307	SSRA_HUMAN	Translocon-associated protein subunit alpha	8050590	The N-terminal region of the alpha-subunit of the TRAP complex has a conserved cluster of negative charges.

Q9WUL5	PD1L2_MOUSE	Programmed cell death 1 ligand 2	11283156	B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells.

P32485	HOG1_YEAST	Mitogen-activated protein kinase HOG1	15448699	Hog1 mediates cell-cycle arrest in G1 phase by the dual targeting of Sic1.

P83623	HBA_PSEUR	Hemoglobin subunit alpha	15340169	Structure and function of the Gondwanian hemoglobin of Pseudaphritis urvillii, a primitive notothenioid fish of temperate latitudes.

Q9Y7J5	YOI9_SCHPO	TBC domain-containing protein C1778.09	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q08457	YO060_YEAST	Mitochondrial morphogenesis protein YOR060C	14562095	Global analysis of protein localization in budding yeast.

Q9MA55	ACBP4_ARATH	Acyl-CoA-binding domain-containing protein 4	19121948	An Arabidopsis family of six acyl-CoA-binding proteins has three cytosolic members.

P30556	AGTR1_HUMAN	Type-1 angiotensin II receptor	1567413	Cloning and characterization of a human angiotensin II type 1 receptor.

Q9VQU9	BOWEL_DROME	Protein bowel	14568103	The Drm-Bowl-Lin relief-of-repression hierarchy controls fore- and hindgut patterning and morphogenesis.

P29208	MENC_ECOLI	o-succinylbenzoate synthase	10194342	Unexpected divergence of enzyme function and sequence: 'N-acylamino acid racemase' is o-succinylbenzoate synthase.

O77203	PIAA_DICDI	Protein pianissimo A	16079174	TOR complex 2 integrates cell movement during chemotaxis and signal relay in Dictyostelium.

P21645	LPXD_ECOLI	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	8366125	The firA gene of Escherichia coli encodes UDP-3-O-(R-3- hydroxymyristoyl)-glucosamine N-acyltransferase. The third step of endotoxin biosynthesis.

P51570	GALK1_HUMAN	Galactokinase	15024738	Biochemical characterization of two GALK1 mutations in patients with galactokinase deficiency.

Q9Y7X9	KIN17_SCHPO	KIN17-like protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P06858	LIPL_HUMAN	Lipoprotein lipase	1969408	Missense mutation (Gly-->Glu188) of human lipoprotein lipase imparting functional deficiency.

Q9NXR7	BRE_HUMAN	BRCA1-A complex subunit BRE	17525341	RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites.

P54609	CD48A_ARATH	Cell division control protein 48 homolog A	8521820	The higher plant Arabidopsis thaliana encodes a functional CDC48 homologue which is highly expressed in dividing and expanding cells.

O74498	UCP10_SCHPO	UBX domain-containing protein 10	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q10059	CDC12_SCHPO	Cell division control protein 12	9105045	cdc12p, a protein required for cytokinesis in fission yeast, is a component of the cell division ring and interacts with profilin.

P31120	GLMM_ECOLI	Phosphoglucosamine mutase	10671448	Autophosphorylation of phosphoglucosamine mutase from Escherichia coli.

P02767	TTHY_RAT	Transthyretin	11995998	Complex of rat transthyretin with tetraiodothyroacetic acid refined at 2.1 and 1.8 A resolution.

Q08548	ALE1_YEAST	Lysophospholipid acyltransferase	14562095	Global analysis of protein localization in budding yeast.

Q9NRI5	DISC1_HUMAN	Disrupted in schizophrenia 1 protein	17035248	DISC1-NDEL1/NUDEL protein interaction, an essential component for neurite outgrowth, is modulated by genetic variations of DISC1.

Q8W487	YB95_ARATH	Uncharacterized protein At2g39795, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P50570	DYN2_HUMAN	Dynamin-2	11583995	Dynamin isoform-specific interaction with the shank/ProSAP scaffolding proteins of the postsynaptic density and actin cytoskeleton.

O88839	ADA15_MOUSE	Disintegrin and metalloproteinase domain-containing protein 15	10531379	Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1.

P40465	CSM2_YEAST	Chromosome segregation in meiosis protein 2	14562095	Global analysis of protein localization in budding yeast.

O96011	PX11B_HUMAN	Peroxisomal membrane protein 11B	9792670	Expression of PEX11beta mediates peroxisome proliferation in the absence of extracellular stimuli.

Q03135	CAV1_HUMAN	Caveolin-1	11865038	Identification and characterization of a novel human plant pathogenesis-related protein that localizes to lipid-enriched microdomains in the Golgi complex.

P39531	RCY1_YEAST	Recyclin-1	10769031	The F-box protein Rcy1p is involved in endocytic membrane traffic and recycling out of an early endosome in Saccharomyces cerevisiae.

P87112	NOT1_SCHPO	General negative regulator of transcription subunit 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q5FBB7	SGOL1_HUMAN	Shugoshin-like 1	16580887	PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation.

Q9UM47	NOTC3_HUMAN	Neurogenic locus notch homolog protein 3	11101851	MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors.

Q06678	RM35_YEAST	54S ribosomal protein L35, mitochondrial	12392552	Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components.

Q6NLQ6	CDPKW_ARATH	Calcium-dependent protein kinase 32	16299177	Arabidopsis calcium-dependent protein kinase AtCPK32 interacts with ABF4, a transcriptional regulator of abscisic acid-responsive gene expression, and modulates its activity.

Q06835	RDS3_YEAST	Pre-mRNA-splicing factor RDS3	14517302	Rds3p is required for stable U2 snRNP recruitment to the splicing apparatus.

O81445	CNBL1_ARATH	Calcineurin B-like protein 1	11230129	The NAF domain defines a novel protein-protein interaction module conserved in Ca(2+)-regulated kinases.

Q96RI1	NR1H4_HUMAN	Bile acid receptor	12917342	BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation.

P52594	AGFG1_HUMAN	Arf-GAP domain and FG repeats-containing protein 1	10613896	The eps15 homology (EH) domain-based interaction between eps15 and hrb connects the molecular machinery of endocytosis to that of nucleocytosolic transport.

P38265	IML3_YEAST	Central kinetochore subunit IML3	12589047	Chl4p and Iml3p are two new members of the budding yeast outer kinetochore.

P32480	HIR2_YEAST	Protein HIR2	9001207	Hir1p and Hir2p function as transcriptional corepressors to regulate histone gene transcription in the Saccharomyces cerevisiae cell cycle.

Q8UVD9	FUBP2_CHICK	Far upstream element-binding protein 2	11781334	A predominantly nuclear protein affecting cytoplasmic localization of beta-actin mRNA in fibroblasts and neurons.

P39053	DYN1_MOUSE	Dynamin-1	12456676	Characterization of endophilin B1b, a brain-specific membrane- associated lysophosphatidic acid acyl transferase with properties distinct from endophilin A1.

O35484	AZIN1_MOUSE	Antizyme inhibitor 1	10698696	Antizyme inhibitor is rapidly induced in growth-stimulated mouse fibroblasts and releases ornithine decarboxylase from antizyme suppression.

P00334	ADH_DROME	Alcohol dehydrogenase	10471707	An exploration of the sequence of a 2.9-Mb region of the genome of Drosophila melanogaster: the Adh region.

Q3I5F7	ACOT6_HUMAN	Putative acyl-coenzyme A thioesterase 6	16940157	Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs.

P17029	ZKSC1_HUMAN	Zinc finger protein with KRAB and SCAN domains 1	7557990	Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders.

P85873	WPMM1_POLMJ	Wasp kinin PMM1	17559065	Identification of three novel peptides isolated from the venom of the neotropical social wasp Polistes major major.

Q8INK6	PGPLB_DROME	Peptidoglycan-recognition protein LB	12845326	Crystal structure of peptidoglycan recognition protein LB from Drosophila melanogaster.

P40356	MED3_YEAST	Mediator of RNA polymerase II transcription subunit 3	9420330	The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain.

Q8WYB5	MYST4_HUMAN	Histone acetyltransferase MYST4	18794358	Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexes.

P02599	CALM_DICDI	Calmodulin	1629238	Association of calmodulin and an unconventional myosin with the contractile vacuole complex of Dictyostelium discoideum.

Q8TAI7	REBL1_HUMAN	GTPase RhebL1	12869548	Identification of dominant negative mutants of Rheb GTPase and their use to implicate the involvement of human Rheb in the activation of p70S6K.

Q27324	RYK1_DROME	Tyrosine-protein kinase Drl	8787750	derailed is required for muscle attachment site selection in Drosophila.

Q22875	SHOC2_CAEEL	Leucine-rich repeat protein soc-2	9618511	Soc-2 encodes a leucine-rich repeat protein implicated in fibroblast growth factor receptor signaling.

Q9CXL1	TM50A_MOUSE	Transmembrane protein 50A	12459264	Entire sequence of a mouse chromosomal segment containing the gene Rhced and a comparative analysis of the homologous human sequence.

O43075	YGWC_SCHPO	UPF0082 protein C8D2.12c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q15743	OGR1_HUMAN	Ovarian cancer G-protein coupled receptor 1	7498459	Cloning, sequencing and tissue distribution of two related G protein- coupled receptor candidates expressed prominently in human lung tissue.

Q9UIF8	BAZ2B_HUMAN	Bromodomain adjacent to zinc finger domain protein 2B	10662543	A novel family of bromodomain genes.

Q9WUU9	MCM3A_MOUSE	80 kDa MCM3-associated protein	10733502	A novel nuclear phosphoprotein, GANP, is up-regulated in centrocytes of the germinal center and associated with MCM3, a protein essential for DNA replication.

Q9Y2A4	ZN443_HUMAN	Zinc finger protein 443	9731181	ZK1, a novel Kruppel-type zinc finger gene, is induced following exposure to ionizing radiation and enhances apoptotic cell death on hematopoietic cells.

A5PLC8	PTMAB_DANRE	Prothymosin alpha-B	18351673	Differential expression of duplicated genes for prothymosin alpha during zebrafish development.

P40568	DSN1_YEAST	Kinetochore-associated protein DSN1	14633972	Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes.

Q04991	FMP42_YEAST	Protein FMP42	14562095	Global analysis of protein localization in budding yeast.

P49893	WN11B_XENLA	Protein Wnt-11b	10751186	The putative Wnt receptor Xenopus frizzled-7 functions upstream of beta-catenin in vertebrate dorso-ventral mesoderm patterning.

P26602	UBIC_ECOLI	Chorismate--pyruvate lyase	1644758	Cloning and sequencing of Escherichia coli ubiC and purification of chorismate lyase.

Q8CFN5	MEF2C_MOUSE	Myocyte-specific enhancer factor 2C	19753306	Sumoylation regulates nuclear localization of lipin-1alpha in neuronal cells.

P0AC13	DHPS_ECOLI	Dihydropteroate synthase	1522070	Cloning, sequencing, and enhanced expression of the dihydropteroate synthase gene of Escherichia coli MC4100.

P86294	PROF_PLAFX	Profilin	19000816	Structural basis for parasite-specific functions of the divergent profilin of Plasmodium falciparum.

Q8BMB3	IF4E2_MOUSE	Eukaryotic translation initiation factor 4E type 2	15153109	Characterization of mammalian eIF4E-family members.

Q9LJN2	MRS23_ARATH	Magnesium transporter MRS2-3	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q27249	TPM3_CAEEL	Tropomyosin isoforms c/e	16399684	Integration of male mating and feeding behaviors in Caenorhabditis elegans.

O43272	PROD_HUMAN	Proline dehydrogenase, mitochondrial	15662599	Functional consequences of PRODH missense mutations.

Q9Y4A5	TRRAP_HUMAN	Transformation/transcription domain-associated protein	11564863	Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage- binding factors in vivo.

P27895	CIN8_YEAST	Kinesin-like protein CIN8	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q8VCW4	UN93B_MOUSE	Protein unc-93 homolog B1	18305481	UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes.

Q8IH24	MED31_DROME	Mediator of RNA polymerase II transcription subunit 31	11259581	Drosophila Mediator complex is broadly utilized by diverse gene- specific transcription factors at different types of core promoters.

Q24323	SEM2A_DROME	Semaphorin-2A	16672342	Drosophila Plexin B is a Sema-2a receptor required for axon guidance.

P64943	PAFA_MYCTU	Pup--protein ligase	14671303	The proteasome of Mycobacterium tuberculosis is required for resistance to nitric oxide.

P55862	MCM5A_XENLA	DNA replication licensing factor mcm5-A	8917078	Identification of two Xenopus laevis genes, xMCM2 and xCDC46, with sequence homology to MCM genes involved in DNA replication.

P10912	GHR_HUMAN	Growth hormone receptor	8943276	Crystal structure of an antagonist mutant of human growth hormone, G120R, in complex with its receptor at 2.9-A resolution.

Q91VF6	EMID2_MOUSE	Collagen alpha-1(XXVI) chain	12221002	Developmental expression and biochemical characterization of Emu family members.

Q9ES52	SHIP1_MOUSE	Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1	8643691	The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase.

P17119	KAR3_YEAST	Kinesin-like protein KAR3	2138512	KAR3, a kinesin-related gene required for yeast nuclear fusion.

Q9Y5Q0	FADS3_HUMAN	Fatty acid desaturase 3	10860662	cDNA cloning, genomic structure, and chromosomal localization of three members of the human fatty acid desaturase family.

Q16288	NTRK3_HUMAN	NT-3 growth factor receptor	7806211	Molecular cloning of the cDNA for human TrkC (NTRK3), chromosomal assignment, and evidence for a splice variant.

B7ZR65	SOX9A_XENLA	Transcription factor Sox-9-A	15084460	Specification of the otic placode depends on Sox9 function in Xenopus.

P50947	PHO23_YEAST	Transcriptional regulatory protein PHO23	10805724	Three yeast proteins related to the human candidate tumor suppressor p33(ING1) are associated with histone acetyltransferase activities.

O15706	VACA_DICDI	Vacuolin-A	9276759	Coronin and vacuolin identify consecutive stages of a late, actin- coated endocytic compartment in Dictyostelium.

P46312	FAD6C_ARATH	Omega-6 fatty acid desaturase, chloroplastic	12766230	Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.

O75427	LRCH4_HUMAN	Leucine-rich repeat and calponin homology domain-containing protein 4	9799793	Large-scale sequencing of two regions in human chromosome 7q22: analysis of 650 kb of genomic sequence around the EPO and CUTL1 loci reveals 17 genes.

P11881	ITPR1_MOUSE	Inositol 1,4,5-trisphosphate receptor type 1	1648733	The subtypes of the mouse inositol 1,4,5-trisphosphate receptor are expressed in a tissue-specific and developmentally specific manner.

Q8W4D8	DDL_ARATH	FHA domain-containing protein DDL	18632581	The FHA domain proteins DAWDLE in Arabidopsis and SNIP1 in humans act in small RNA biogenesis.

P40989	FKS2_YEAST	1,3-beta-glucan synthase component GSC2	7649185	Characterization and gene cloning of 1,3-beta-D-glucan synthase from Saccharomyces cerevisiae.

P54821	PRRX1_HUMAN	Paired mesoderm homeobox protein 1	1509260	Human and Drosophila homeodomain proteins that enhance the DNA- binding activity of serum response factor.

O95967	FBLN4_HUMAN	EGF-containing fibulin-like extracellular matrix protein 2	10601734	Sequence, recombinant expression and tissue localization of two novel extracellular matrix proteins, fibulin-3 and fibulin-4.

Q8K2V6	IPO11_MOUSE	Importin-11	11809816	Ribosomal protein L12 uses a distinct nuclear import pathway mediated by importin 11.

Q9R0U1	IP6K2_RAT	Inositol hexakisphosphate kinase 2	10527952	Regulation of intestinal Na+-dependent phosphate co-transporters by a low-phosphate diet and 1,25-dihydroxyvitamin D3.

Q15003	CND2_HUMAN	Condensin complex subunit 2	11136719	Chromosome condensation by a human condensin complex in Xenopus egg extracts.

P20448	DBP4_YEAST	ATP-dependent RNA helicase DBP4	16209945	The putative RNA helicase Dbp4p is required for release of the U14 snoRNA from preribosomes in Saccharomyces cerevisiae.

Q04695	K1C17_HUMAN	Keratin, type I cytoskeletal 17	7539673	Keratin 16 and keratin 17 mutations cause pachyonychia congenita.

O88563	MRP3_RAT	Canalicular multispecific organic anion transporter 2	10362653	MRP3, a new ATP-binding cassette protein localized to the canalicular domain of the hepatocyte.

Q9UKB1	FBW1B_HUMAN	F-box/WD repeat-containing protein 11	16880511	Regulation of p27 degradation and S-phase progression by Ro52 RING finger protein.

O14983	AT2A1_HUMAN	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	10914677	The mutation of Pro(789) to Leu reduces the activity of the fast- twitch skeletal muscle sarco(endo)plasmic reticulum Ca(2+) ATPase (SERCA1) and is associated with Brody disease.

Q8WTE6	OR2_ANOGA	Odorant receptor Or2	14724626	Olfaction: mosquito receptor for human-sweat odorant.

O13985	YEG3_SCHPO	Uncharacterized WD repeat-containing protein C26H5.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P23242	CXA1_MOUSE	Gap junction alpha-1 protein	19864490	Consortin, a trans-Golgi network cargo receptor for the plasma membrane targeting and recycling of connexins.

O43868	S28A2_HUMAN	Sodium/nucleoside cotransporter 2	9435697	Na+-dependent purine nucleoside transporter from human kidney: cloning and functional characterization.

P0ADV1	LPTA_ECOLI	Lipopolysaccharide export system protein lptA	17056748	Characterization of lptA and lptB, two essential genes implicated in lipopolysaccharide transport to the outer membrane of Escherichia coli.

Q9FDX1	SKIP1_ARATH	F-box protein SKIP1	11387208	SKP1-SnRK protein kinase interactions mediate proteasomal binding of a plant SCF ubiquitin ligase.

O81770	MGDG1_ARATH	Monogalactosyldiacylglycerol synthase 1, chloroplastic	11553816	Two types of MGDG synthase genes, found widely in both 16:3 and 18:3 plants, differentially mediate galactolipid syntheses in photosynthetic and nonphotosynthetic tissues in Arabidopsis thaliana.

P40061	TSC11_YEAST	Target of rapamycin complex 2 subunit TSC11	12408816	Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control.

P17106	CBF1_YEAST	Centromere-binding protein 1	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q7TS99	HELT_MOUSE	Hairy and enhancer of split-related protein HELT	14764602	Helt, a novel basic-helix-loop-helix transcriptional repressor expressed in the developing central nervous system.

Q15173	2A5B_HUMAN	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform	8703017	The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm.

P04637	P53_HUMAN	Cellular tumor antigen p53	16474402	Molecular recognition of p53 and MDM2 by USP7/HAUSP.

O70597	PX11A_RAT	Peroxisomal membrane protein 11A	9548716	Peroxisome biogenesis: involvement of ARF and coatomer.

P49789	FHIT_HUMAN	Bis(5'-adenosyl)-triphosphatase	8794732	Fhit, a putative tumor suppressor in humans, is a dinucleoside 5',5''-P1,P3-triphosphate hydrolase.

P0A8Y8	YBDB_ECOLI	Esterase ybdB	15808744	Enzyme genomics: application of general enzymatic screens to discover new enzymes.

O94811	TPPP_HUMAN	Tubulin polymerization-promoting protein	17105200	Tubulin polymerization promoting proteins (TPPPs): members of a new family with distinct structures and functions.

Q6MGD0	CUTA_RAT	Protein CutA	12949080	The evolutionarily conserved trimeric structure of CutA1 proteins suggests a role in signal transduction.

P21306	ATP5E_YEAST	ATP synthase subunit epsilon, mitochondrial	8416924	ATP synthase of yeast mitochondria. Isolation and disruption of the ATP epsilon gene.

O61125	STK4_DICDI	Serine/threonine-protein kinase 4 homolog A	16842885	Characterization of the Ste20-like kinase Krs1 of Dictyostelium discoideum.

Q9XTG7	AKT2_CAEEL	Serine/threonine-protein kinase akt-2	15068796	C. elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span.

O15031	PLXB2_HUMAN	Plexin-B2	15184888	Interplay between scatter factor receptors and B plexins controls invasive growth.

P40475	QDR1_YEAST	Quinidine resistance protein 1	11302822	Resistance and adaptation to quinidine in Saccharomyces cerevisiae: role of QDR1 (YIL120w), encoding a plasma membrane transporter of the major facilitator superfamily required for multidrug resistance.

Q16099	GRIK4_HUMAN	Glutamate receptor, ionotropic kainate 4	8263508	Molecular cloning, expression, and pharmacological characterization of humEAA1, a human kainate receptor subunit.

Q16827	PTPRO_HUMAN	Receptor-type tyrosine-protein phosphatase O	7753550	Cloning, expression and chromosomal localization of a novel gene for protein tyrosine phosphatase (PTP-U2) induced by various differentiation-inducing agents.

P02774	VTDB_HUMAN	Vitamin D-binding protein	11799400	A structural basis for the unique binding features of the human vitamin D-binding protein.

Q8T115	HCYC_SCUCO	Hemocyanin subunit C	12823556	Complete subunit sequences, structure and evolution of the 6 x 6-mer hemocyanin from the common house centipede, Scutigera coleoptrata.

O13539	THP2_YEAST	THO complex subunit THP2	11979277	TREX is a conserved complex coupling transcription with messenger RNA export.

O55101	SNG2_MOUSE	Synaptogyrin-2	12928441	Cellugyrin and synaptogyrin facilitate targeting of synaptophysin to a ubiquitous synaptic vesicle-sized compartment in PC12 cells.

P52597	HNRPF_HUMAN	Heterogeneous nuclear ribonucleoprotein F	7499401	Heterogeneous nuclear ribonucleoproteins H, H', and F are members of a ubiquitously expressed subfamily of related but distinct proteins encoded by genes mapping to different chromosomes.

Q96NY9	MUS81_HUMAN	Crossover junction endonuclease MUS81	19596236	Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases.

P56093	TUP1_CANAL	Transcriptional repressor TUP1	9204892	Control of filament formation in Candida albicans by the transcriptional repressor TUP1.

Q12158	SCC1_YEAST	Sister chromatid cohesion protein 1	9990856	Yeast cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication.

P47739	AL3A1_MOUSE	Aldehyde dehydrogenase, dimeric NADP-preferring	10376761	Four amino acid changes are associated with the Aldh3a1 locus polymorphism in mice which may be responsible for corneal sensitivity to ultraviolet light.

Q8BLF1	ADCL1_MOUSE	Neutral cholesterol ester hydrolase 1	15840715	A brain detoxifying enzyme for organophosphorus nerve poisons.

Q03640	TCB3_YEAST	Tricalbin-3	15049706	The tricalbin C2 domains: lipid-binding properties of a novel, synaptotagmin-like yeast protein family.

P97496	SMRC1_MOUSE	SWI/SNF complex subunit SMARCC1	11604513	Srg3, a mouse homolog of yeast SWI3, is essential for early embryogenesis and involved in brain development.

O00762	UBE2C_HUMAN	Ubiquitin-conjugating enzyme E2 C	19822757	Identification of a physiological E2 module for the human anaphase- promoting complex.

P40485	SLM1_YEAST	Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1	15689497	The pleckstrin homology domain proteins Slm1 and Slm2 are required for actin cytoskeleton organization in yeast and bind phosphatidylinositol-4,5-bisphosphate and TORC2.

Q9SYX2	SPA1_ARATH	Protein SUPPRESSOR OF PHYA-105 1	10205059	SPA1, a WD-repeat protein specific to phytochrome A signal transduction.

P26010	ITB7_HUMAN	Integrin beta-7	2040616	Complete amino acid sequence of an integrin beta subunit (beta 7) identified in leukocytes.

Q9H222	ABCG5_HUMAN	ATP-binding cassette sub-family G member 5	11099417	Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters.

Q03362	YD476_YEAST	Uncharacterized protein YDR476C	14562095	Global analysis of protein localization in budding yeast.

Q8K202	RPA49_MOUSE	DNA-directed RNA polymerase I subunit RPA49	8641287	RNA polymerase I associated factor 53 binds to the nucleolar transcription factor UBF and functions in specific rDNA transcription.

Q08965	BMS1_YEAST	Ribosome biogenesis protein BMS1	11565748	Bms1p, a G-domain-containing protein, associates with Rcl1p and is required for 18S rRNA biogenesis in yeast.

O15530	PDPK1_HUMAN	3-phosphoinositide-dependent protein kinase 1	9368760	3-phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase.

P27797	CALR_HUMAN	Calreticulin	7841019	Human placental calreticulin: purification, characterization and association with other proteins.

Q98867	THAA_DANRE	Thyroid hormone receptor alpha-A	17583703	An F-domain introduced by alternative splicing regulates activity of the zebrafish thyroid hormone receptor alpha.

Q05195	MAD1_HUMAN	Max dimerization protein 1	8425218	Mad: a heterodimeric partner for Max that antagonizes Myc transcriptional activity.

P40518	ARPC5_YEAST	Actin-related protein 2/3 complex subunit 5	11248049	Arp2/3 complex and actin dynamics are required for actin-based mitochondrial motility in yeast.

P52565	GDIR1_HUMAN	Rho GDP-dissociation inhibitor 1	8262133	Identification of two human Rho GDP dissociation inhibitor proteins whose overexpression leads to disruption of the actin cytoskeleton.

P38666	RL242_ARATH	60S ribosomal protein L24-2	16227452	The Arabidopsis STV1 protein, responsible for translation reinitiation, is required for auxin-mediated gynoecium patterning.

P00747	PLMN_HUMAN	Plasminogen	2318848	Characterization of the gene for human plasminogen, a key proenzyme in the fibrinolytic system.

P30775	RF1M_YEAST	Peptide chain release factor 1, mitochondrial	16321977	The yeast translation release factors Mrf1p and Sup45p (eRF1) are methylated, respectively, by the methyltransferases Mtq1p and Mtq2p.

Q07959	IZH3_YEAST	ADIPOR-like receptor IZH3	14562095	Global analysis of protein localization in budding yeast.

P07249	ARGR1_YEAST	Arginine metabolism regulation protein I	3298999	Characterization of two genes, ARGRI and ARGRIII required for specific regulation of arginine metabolism in yeast.

P27800	ALDX_SPOSA	Aldehyde reductase 1	8779568	Cloning of the aldehyde reductase gene from a red yeast, Sporobolomyces salmonicolor, and characterization of the gene and its product.

Q9VSY6	SERB_DROME	Phosphoserine phosphatase	11102367	Mutations affecting the development of the peripheral nervous system in Drosophila: a molecular screen for novel proteins.

P53166	MRH4_YEAST	ATP-dependent RNA helicase MRH4, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

O76932	PP4C_DROME	Serine/threonine-protein phosphatase 4 catalytic subunit	9570751	Protein phosphatase 4 is an essential enzyme required for organisation of microtubules at centrosomes in Drosophila embryos.

Q9VTG7	B3G2P_DROME	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase P	12511570	Identification and characterization of three Drosophila melanogaster glucuronyltransferases responsible for the synthesis of the conserved glycosaminoglycan-protein linkage region of proteoglycans: two novel homologs exhibit broad specificity toward oligosaccharides from proteoglycans, glycoproteins, and glycosphingolipids.

P28629	ADIA_ECOLI	Biodegradative arginine decarboxylase	4204273	Chemical properties of Escherichia coli lysine decarboxylase including a segment of its pyridoxal 5'-phosphate binding site.

Q76KP1	B4GN4_HUMAN	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1	15044014	Molecular cloning and characterization of beta1,4-N- acetylgalactosaminyltransferases IV synthesizing N,N'- diacetyllactosediamine.

Q9UKK9	NUDT5_HUMAN	ADP-sugar pyrophosphatase	10722730	Cloning and characterization of a new member of the Nudix hydrolases from human and mouse.

Q96HE7	ERO1A_HUMAN	ERO1-like protein alpha	10671517	ERO1-L, a human protein that favors disulfide bond formation in the endoplasmic reticulum.

P07359	GP1BA_HUMAN	Platelet glycoprotein Ib alpha chain	12183630	Structures of glycoprotein Ibalpha and its complex with von Willebrand factor A1 domain.

P05783	K1C18_HUMAN	Keratin, type I cytoskeletal 18	2434380	Comparison of mouse and human keratin 18: a component of intermediate filaments expressed prior to implantation.

Q9LX66	HERK_ARATH	Receptor-like protein kinase HERK 1	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q8BH60	GOPC_MOUSE	Golgi-associated PDZ and coiled-coil motif-containing protein	12885772	CALEB/NGC interacts with the Golgi-associated protein PIST.

Q9XZT6	DNK_DROME	Deoxynucleoside kinase	10446143	Cloning and characterization of the multisubstrate deoxyribonucleoside kinase of Drosophila melanogaster.

P17076	RL8A_YEAST	60S ribosomal protein L8-A	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q9S7U9	M2K2_ARATH	Mitogen-activated protein kinase kinase 2	15225555	The MKK2 pathway mediates cold and salt stress signaling in Arabidopsis.

Q96BD8	SKA1_HUMAN	Spindle and kinetochore-associated protein 1	19289083	The human kinetochore Ska1 complex facilitates microtubule depolymerization-coupled motility.

Q05583	CIAO1_YEAST	Cytosolic iron-sulfur protein assembly protein 1	17937914	Structure of the yeast WD40 domain protein Cia1, a component acting late in iron-sulfur protein biogenesis.

P54777	PEX6_RAT	Peroxisome assembly factor 2	7493019	Peroxisome assembly factor-2, a putative ATPase cloned by functional complementation on a peroxisome-deficient mammalian cell mutant.

P06992	RSMA_ECOLI	Ribosomal RNA small subunit methyltransferase A	18990185	Mechanistic insight into the ribosome biogenesis functions of the ancient protein KsgA.

Q42438	CDPK8_ARATH	Calcium-dependent protein kinase 8	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q13347	EIF3I_HUMAN	Eukaryotic translation initiation factor 3 subunit I	17322308	Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry.

O54852	KCNH7_RAT	Potassium voltage-gated channel subfamily H member 7	11212207	Erg1, erg2 and erg3 K channel subunits are able to form heteromultimers.

Q8WWY3	PRP31_HUMAN	U4/U6 small nuclear ribonucleoprotein Prp31	11867543	Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6.U5 tri-snRNP formation and pre-mRNA splicing.

Q54E04	VATM_DICDI	Vacuolar proton translocating ATPase 100 kDa subunit	11956322	Altered expression of the 100 kDa subunit of the Dictyostelium vacuolar proton pump impairs enzyme assembly, endocytic function and cytosolic pH regulation.

P48163	MAOX_HUMAN	NADP-dependent malic enzyme	7622060	Cloning, sequencing and functional expression of a cDNA encoding a NADP-dependent malic enzyme from human liver.

P51570	GALK1_HUMAN	Galactokinase	12694189	Functional analysis of disease-causing mutations in human galactokinase.

P46689	GASA1_ARATH	Gibberellin-regulated protein 1	7727751	GASA, a gibberellin-regulated gene family from Arabidopsis thaliana related to the tomato GAST1 gene.

P36164	TVP38_YEAST	Golgi apparatus membrane protein TVP38	17178117	Tvp38, Tvp23, Tvp18 and Tvp15: novel membrane proteins in the Tlg2- containing Golgi/endosome compartments of Saccharomyces cerevisiae.

Q9P0L2	MARK1_HUMAN	Serine/threonine-protein kinase MARK1	14976552	LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1.

Q9HAU0	PKHA5_HUMAN	Pleckstrin homology domain-containing family A member 5	11001876	Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities.

Q15319	PO4F3_HUMAN	POU domain, class 4, transcription factor 3	9506947	Mutation in transcription factor POU4F3 associated with inherited progressive hearing loss in humans.

Q9NR81	ARHG3_HUMAN	Rho guanine nucleotide exchange factor 3	10873612	Isolation of two novel human RhoGEFs, ARHGEF3 and ARHGEF4, in 3p13-21 and 2q22.

Q9GZP8	IMUP_HUMAN	Immortalization up-regulated protein	11080599	Identification of cDNAs encoding two novel nuclear proteins, IMUP-1 and IMUP-2, upregulated in SV40-immortalized human fibroblasts.

P17798	VIRB8_AGRT5	Protein virB8	2233252	Characterization of the virB operon of an Agrobacterium tumefaciens Ti plasmid: nucleotide sequence and protein analysis.

Q90Z12	HES4A_XENLA	Transcription factor HES-4-A	17724611	Two alloalleles of Xenopus laevis hairy2 gene-evolution of duplicated gene function from a developmental perspective.

Q9HGP1	YNK4_SCHPO	Uncharacterized protein C29B5.04c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12830	BPTF_HUMAN	Nucleosome-remodeling factor subunit BPTF	7621746	FAC1, a novel gene identified with the monoclonal antibody Alz50, is developmentally regulated in human brain.

Q9UTL5	TF3A_SCHPO	Transcription factor IIIA	12087160	Identification and characterization of transcription factor IIIA from Schizosaccharomyces pombe.

O95551	TYDP2_HUMAN	Tyrosyl-DNA phosphodiesterase 2	19794497	A human 5'-tyrosyl DNA phosphodiesterase that repairs topoisomerase- mediated DNA damage.

Q39128	KAT1_ARATH	Potassium channel KAT1	1570292	Functional expression of a probable Arabidopsis thaliana potassium channel in Saccharomyces cerevisiae.

P41263	RET4_CHICK	Retinol-binding protein 4	7748490	Retinol in avian oogenesis: molecular properties of the carrier protein.

Q8WVQ1	CANT1_HUMAN	Soluble calcium-activated nucleotidase 1	12761501	Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.

Q06469	CUR1_YEAST	Curing of [URE3] protein 1	18833194	Curing of the [URE3] prion by Btn2p, a Batten disease-related protein.

Q9WVR4	FXR2_MOUSE	Fragile X mental retardation syndrome-related protein 2	11438699	A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P.

A6X982	YOGD_SCHPO	Uncharacterized protein C15D4.13c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O13691	NDUV2_SCHPO	NADH-ubiquinone oxidoreductase 24 kDa subunit homolog C11E3.12, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q7KHG2	JING_DROME	Zinc finger protein jing	16510782	jing is required for wing development and to establish the proximo- distal axis of the leg in Drosophila melanogaster.

P32851	STX1A_RAT	Syntaxin-1A	1334074	HPC-1 is associated with synaptotagmin and omega-conotoxin receptor.

P35638	DDIT3_HUMAN	DNA damage-inducible transcript 3 protein	8510758	Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma.

Q9VF26	SPNE_DROME	Probable ATP-dependent RNA helicase spindle-E	14752161	Heterochromatic silencing and HP1 localization in Drosophila are dependent on the RNAi machinery.

O15118	NPC1_HUMAN	Niemann-Pick C1 protein	10521290	Mutations in NPC1 highlight a conserved NPC1-specific cysteine-rich domain.

Q9BSG1	ZNF2_HUMAN	Zinc finger protein 2	1945843	Members of the zinc finger protein gene family sharing a conserved N- terminal module.

P34998	CRFR1_HUMAN	Corticotropin-releasing factor receptor 1	8243652	Primary structure and functional expression of mouse pituitary and human brain corticotrophin releasing factor receptors.

Q9ERR1	NDEL1_MOUSE	Nuclear distribution protein nudE-like 1	11163260	NUDEL is a novel cdk5 substrate that associates with LIS1 and cytoplasmic dynein.

Q98998	5HT1A_XENLA	5-hydroxytryptamine receptor 1A	9221903	Cloning and developmental expression of 5-HT1A receptor gene in Xenopus laevis.

P27101	TCBF_PSESQ	Maleylacetate reductase	2013566	Sequence analysis of the Pseudomonas sp. strain P51 tcb gene cluster, which encodes metabolism of chlorinated catechols: evidence for specialization of catechol 1,2-dioxygenases for chlorinated substrates.

Q54JA5	SIBC_DICDI	Integrin beta-like protein C	16699495	An adhesion molecule in free-living Dictyostelium amoebae with integrin beta features.

P08631	HCK_HUMAN	Tyrosine-protein kinase HCK	3496523	Identification of a human gene (HCK) that encodes a protein-tyrosine kinase and is expressed in hemopoietic cells.

O42894	RRP46_SCHPO	Exosome complex component rrp46	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q5B7U0	PMEA_EMENI	Pectinesterase A	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

P36146	LAS1_YEAST	Protein LAS1	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q80VW5	WHRN_MOUSE	Whirlin	17326148	The deaf mouse mutant whirler suggests a role for whirlin in actin filament dynamics and stereocilia development.

Q86UP2	KTN1_HUMAN	Kinectin	7787243	Molecular cloning and characterization of human kinectin.

O43592	XPOT_HUMAN	Exportin-T	9660920	Identification of a tRNA-specific nuclear export receptor.

Q04980	LTI65_ARATH	Low-temperature-induced 65 kDa protein	8437577	Characterization of the expression of a desiccation-responsive rd29 gene of Arabidopsis thaliana and analysis of its promoter in transgenic plants.

P39552	MST28_YEAST	Multicopy suppressor of SEC21 protein 28	12925749	Suppression of coatomer mutants by a new protein family with COPI and COPII binding motifs in Saccharomyces cerevisiae.

O95983	MBD3_HUMAN	Methyl-CpG-binding domain protein 3	12183469	Two highly related p66 proteins comprise a new family of potent transcriptional repressors interacting with MBD2 and MBD3.

Q9HDU8	YHE7_SCHPO	UPF0494 membrane protein PB2B2.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P54999	RUXF_YEAST	Small nuclear ribonucleoprotein F	9012791	Identification of the proteins of the yeast U1 small nuclear ribonucleoprotein complex by mass spectrometry.

Q16515	ACCN1_HUMAN	Amiloride-sensitive cation channel 1, neuronal	11802773	Interaction of the synaptic protein PICK1 (protein interacting with C kinase 1) with the non-voltage gated sodium channels BNC1 (brain Na+ channel 1) and ASIC (acid-sensing ion channel).

P84865	MT1_NECLU	Metallothionein	15939401	Cadmium induces a novel metallothionein and phytochelatin 2 in an aquatic fungus.

O00142	KITM_HUMAN	Thymidine kinase 2, mitochondrial	9079672	Cloning of the cDNA and chromosome localization of the gene for human thymidine kinase 2.

P49959	MRE11_HUMAN	Double-strand break repair protein MRE11A	10612394	The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder.

Q03579	LIP1_YEAST	Ceramide synthase subunit LIP1	15692566	Lip1p: a novel subunit of acyl-CoA ceramide synthase.

Q9Y738	MIS12_SCHPO	Centromere protein mis12	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9CXW3	CYBP_MOUSE	Calcyclin-binding protein	11927578	Ca2+-dependent translocation of the calcyclin-binding protein in neurons and neuroblastoma NB-2a cells.

Q9SZR1	ACA10_ARATH	Calcium-transporting ATPase 10, plasma membrane-type	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q07960	RHG01_HUMAN	Rho GTPase-activating protein 1	12901880	BNIPL-2, a novel homologue of BNIP-2, interacts with Bcl-2 and Cdc42GAP in apoptosis.

Q07998	BRACA_DANRE	Brachyury protein homolog A	1295726	The protein product of the zebrafish homologue of the mouse T gene is expressed in nuclei of the germ ring and the notochord of the early embryo.

Q44336	FLGC_AGRT5	Flagellar basal-body rod protein flgC	9161424	Isolation and characterisation of a linked cluster of genes from Agrobacterium tumefaciens encoding proteins involved in flagellar basal-body structure.

Q12343	MED4_YEAST	Mediator of RNA polymerase II transcription subunit 4	9420330	The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain.

Q9SSM7	PYL3_ARATH	Abscisic acid receptor PYL3	19407142	Abscisic acid inhibits type 2C protein phosphatases via the PYR/PYL family of START proteins.

P38164	YBK4_YEAST	WD repeat-containing protein YBL104C	14562095	Global analysis of protein localization in budding yeast.

O43813	LANC1_HUMAN	LanC-like protein 1	10944443	Characterization of p40/GPR69A as a peripheral membrane protein related to the lantibiotic synthetase component C.

Q9US49	SGT1_SCHPO	Protein sgt1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Z1H9	PRDBP_RAT	Protein kinase C delta-binding protein	9054438	A protein kinase Cdelta-binding protein SRBC whose expression is induced by serum starvation.

Q9R229	BMP10_MOUSE	Bone morphogenetic protein 10	16798733	Overexpression of bone morphogenetic protein 10 in myocardium disrupts cardiac postnatal hypertrophic growth.

Q12288	YL126_YEAST	Putative glutamine amidotransferase YLR126C	14534306	Exploratory and confirmatory gene expression profiling of mac1Delta.

Q6DRL4	TICRR_DANRE	Treslin	20080954	A vertebrate gene, ticrr, is an essential checkpoint and replication regulator.

Q9NWT8	AKIP_HUMAN	Aurora kinase A-interacting protein	12244051	Aurora-A kinase interacting protein (AIP), a novel negative regulator of human Aurora-A kinase.

P38405	GNAL_HUMAN	Guanine nucleotide-binding protein G(olf) subunit alpha	8243272	Human G(olf) alpha: complementary deoxyribonucleic acid structure and expression in pancreatic islets and other tissues outside the olfactory neuroepithelium and central nervous system.

Q9C641	EFGM_ARATH	Elongation factor G, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P38797	PP2C7_YEAST	Protein phosphatase 2C homolog 7, mitochondrial	12220683	The YHR076w gene encodes a type 2C protein phosphatase and represents the seventh PP2C gene in budding yeast.

Q5XPJ9	SCAR2_ARATH	Protein SCAR2	17267444	The role of Arabidopsis SCAR genes in ARP2-ARP3-dependent cell morphogenesis.

Q38954	PHT21_ARATH	Inorganic phosphate transporter 2-1, chloroplastic	10559441	Pht2;1 encodes a low-affinity phosphate transporter from Arabidopsis.

O74861	SDC1_SCHPO	Set1 complex component sdc1	12488447	High conservation of the Set1/Rad6 axis of histone 3 lysine 4 methylation in budding and fission yeasts.

Q99697	PITX2_HUMAN	Pituitary homeobox 2	9618168	Mutation in the RIEG1 gene in patients with iridogoniodysgenesis syndrome.

P38991	IPL1_YEAST	Spindle assembly checkpoint kinase	10975519	Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes.

Q01663	AP1_SCHPO	AP-1-like transcription factor	1899230	Fission yeast genes that confer resistance to staurosporine encode an AP-1-like transcription factor and a protein kinase related to the mammalian ERK1/MAP2 and budding yeast FUS3 and KSS1 kinases.

Q99260	YPT6_YEAST	GTP-binding protein YPT6	11785952	Saccharomyces cerevisiae Pra1p/Yip3p interacts with Yip1p and Rab proteins.

Q9P7T1	SIB1_SCHPO	Hydroxamate-type ferrichrome siderophore peptide synthetase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q920A7	AFG31_MOUSE	AFG3-like protein 1	11549317	Molecular and functional analyses of the human and mouse genes encoding AFG3L1, a mitochondrial metalloprotease homologous to the human spastic paraplegia protein.

Q7XJE6	MCA1_ARATH	Metacaspase-1	15691845	Two Arabidopsis metacaspases AtMCP1b and AtMCP2b are arginine/lysine- specific cysteine proteases and activate apoptosis-like cell death in yeast.

Q9SDY5	RCE1_ARATH	NEDD8-conjugating enzyme Ubc12	12682009	The RUB/Nedd8 conjugation pathway is required for early development in Arabidopsis.

Q61085	RHPN1_MOUSE	Rhophilin-1	8571126	Protein kinase N (PKN) and PKN-related protein rhophilin as targets of small GTPase Rho.

P06776	PDE2_YEAST	3',5'-cyclic-nucleotide phosphodiesterase 2	3025832	Cloning and characterization of the high-affinity cAMP phosphodiesterase of Saccharomyces cerevisiae.

P06243	CDC7_YEAST	Cell division control protein 7	1865880	CDC7 protein kinase activity is required for mitosis and meiosis in Saccharomyces cerevisiae.

P06104	UBC2_YEAST	Ubiquitin-conjugating enzyme E2 2	15632065	Histone H2B ubiquitylation is associated with elongating RNA polymerase II.

Q9Y048	DTN1_CAEEL	Dystrobrevin-1	10561496	In vitro interactions of Caenorhabditis elegans dystrophin with dystrobrevin and syntrophin.

Q96FC9	DDX11_HUMAN	Probable ATP-dependent RNA helicase DDX11	8798685	The human homologue of the yeast CHL1 gene is a novel keratinocyte growth factor regulated gene.

Q9H0N5	PHS2_HUMAN	Pterin-4-alpha-carbinolamine dehydratase 2	11980910	Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha.

Q9VBV3	TAKT_DROME	Protein takeout	10958689	takeout, a novel Drosophila gene under circadian clock transcriptional regulation.

Q9QXA1	CYHR1_MOUSE	Cysteine and histidine-rich protein 1	10745073	Interaction of a novel cysteine and histidine-rich cytoplasmic protein with galectin-3 in a carbohydrate-independent manner galectin 3.

Q9UTH3	PPK6_SCHPO	Serine/threonine-protein kinase ppk6	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O94675	MAM33_SCHPO	Mitochondrial acidic protein mam33	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q08981	ACM1_YEAST	APC/C-CDH1 modulator 1	17030612	Acm1 is a negative regulator of the CDH1-dependent anaphase-promoting complex/cyclosome in budding yeast.

Q940J1	ATB16_ARATH	Homeobox-leucine zipper protein ATHB-16	16055682	Homeodomain leucine zipper class I genes in Arabidopsis. Expression patterns and phylogenetic relationships.

P19388	RPAB1_HUMAN	DNA-directed RNA polymerases I, II, and III subunit RPABC1	7828586	Human RPB5, a subunit shared by eukaryotic nuclear RNA polymerases, binds human hepatitis B virus X protein and may play a role in X transactivation.

Q9NYJ8	TAB2_HUMAN	TGF-beta-activated kinase 1 and MAP3K7-binding protein 2	17449468	RBCK1 negatively regulates tumor necrosis factor- and interleukin-1- triggered NF-kappaB activation by targeting TAB2/3 for degradation.

P45983	MK08_HUMAN	Mitogen-activated protein kinase 8	10856240	The evi-1 oncoprotein inhibits c-Jun N-terminal kinase and prevents stress-induced cell death.

O13600	SWS1_SCHPO	Zinc finger SWIM domain-containing protein sws1	16710300	Sws1 is a conserved regulator of homologous recombination in eukaryotic cells.

P60520	GBRL2_HUMAN	Gamma-aminobutyric acid receptor-associated protein-like 2	11146101	Interaction of the Unc-51-like kinase and microtubule-associated protein light chain 3 related proteins in the brain: possible role of vesicular transport in axonal elongation.

Q62232	SIX2_MOUSE	Homeobox protein SIX2	8814301	Identification and expression of Six family genes in mouse retina.

P92964	RSP31_ARATH	Arginine/serine-rich-splicing factor RSP31	8989882	Characterization of a novel arginine/serine-rich splicing factor in Arabidopsis.

P35187	SGS1_YEAST	ATP-dependent helicase SGS1	15899853	Yeast Rmi1/Nce4 controls genome stability as a subunit of the Sgs1- Top3 complex.

Q08473	SQD_DROME	RNA-binding protein squid	7684991	Initial organization of the Drosophila dorsoventral axis depends on an RNA-binding protein encoded by the squid gene.

P30191	GBRA6_RAT	Gamma-aminobutyric acid receptor subunit alpha-6	2166916	Cerebellar GABAA receptor selective for a behavioural alcohol antagonist.

Q7L2H7	EIF3M_HUMAN	Eukaryotic translation initiation factor 3 subunit M	17322308	Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry.

Q84NN4	CDSP_ORYSJ	Thioredoxin-like protein CDSP32, chloroplastic	16891402	Rice NTRC is a high-efficiency redox system for chloroplast protection against oxidative damage.

Q949X7	DCDA1_ARATH	Diaminopimelate decarboxylase 1, chloroplastic	15652176	Biosynthesis of lysine in plants: evidence for a variant of the known bacterial pathways.

P68372	TBB2C_MOUSE	Tubulin beta-2C chain	3782288	The mammalian beta-tubulin repertoire: hematopoietic expression of a novel, heterologous beta-tubulin isotype.

P63006	LHX1_MOUSE	LIM/homeobox protein Lhx1	8793615	The LIM homeodomain protein Lim-1 is widely expressed in neural, neural crest and mesoderm derivatives in vertebrate development.

P41543	OST1_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1	9405463	The highly conserved Stt3 protein is a subunit of the yeast oligosaccharyltransferase and forms a subcomplex with Ost3p and Ost4p.

O35098	DPYL4_MOUSE	Dihydropyrimidinase-related protein 4	10956643	Molecular characterization of CRMP5, a novel member of the collapsin response mediator protein family.

O18209	PMY13_CAEEL	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase wee-1.3	11702779	Two zinc finger proteins, OMA-1 and OMA-2, are redundantly required for oocyte maturation in C. elegans.

P50537	MAE1_SCHPO	Malic acid transport protein	8750236	The mae1 gene of Schizosaccharomyces pombe encodes a permease for malate and other C4 dicarboxylic acids.

O94277	PABS_SCHPO	Putative aminodeoxychorismate synthase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O00167	EYA2_HUMAN	Eyes absent homolog 2	9020840	A human homologue of the Drosophila eyes absent gene underlies branchio-oto-renal (BOR) syndrome and identifies a novel gene family.

Q96QZ7	MAGI1_HUMAN	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1	14627983	Carom: a novel membrane-associated guanylate kinase-interacting protein with two SH3 domains.

A4GSN8	NUA_ARATH	Nuclear-pore anchor	17513499	NUCLEAR PORE ANCHOR, the Arabidopsis homolog of Tpr/Mlp1/Mlp2/megator, is involved in mRNA export and SUMO homeostasis and affects diverse aspects of plant development.

P53845	YIF1_YEAST	Protein transport protein YIF1	11943201	Identification of the novel proteins Yip4p and Yip5p as Rab GTPase interacting factors.

P53299	TIM13_YEAST	Mitochondrial import inner membrane translocase subunit TIM13	12221072	The role of the Tim8p-Tim13p complex in a conserved import pathway for mitochondrial polytopic inner membrane proteins.

Q62767	DUS4_RAT	Dual specificity protein phosphatase 4	7782322	A novel mitogen-activated protein kinase phosphatase. Structure, expression, and regulation.

P53996	CNBP_MOUSE	Cellular nucleic acid-binding protein	12706888	Molecular cloning, developmental expression, promoter analysis and functional characterization of the mouse CNBP gene.

Q9JIY7	NAT8_MOUSE	N-acetyltransferase 8	11397015	Overexpression of camello, a member of a novel protein family, reduces blastomere adhesion and inhibits gastrulation in Xenopus laevis.

A4GZV0	DBLOH_XENLA	Diablo homolog, mitochondrial	17336467	Cloning and characterization of Xenopus laevis Smac/DIABLO.

Q86B61	TBH1_DROME	Tyramine beta-hydroxylase	14623230	Distinct octopamine cell population residing in the CNS abdominal ganglion controls ovulation in Drosophila melanogaster.

P06244	KAPA_YEAST	cAMP-dependent protein kinase type 1	2823100	Characterization of Saccharomyces cerevisiae genes encoding subunits of cyclic AMP-dependent protein kinase.

P52850	NDST2_MOUSE	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2	10466727	Abnormal mast cells in mice deficient in a heparin-synthesizing enzyme.

Q60680	IKKA_MOUSE	Inhibitor of nuclear factor kappa-B kinase subunit alpha	10733566	Functional isoforms of IkappaB kinase alpha (IKKalpha) lacking leucine zipper and helix-loop-helix domains reveal that IKKalpha and IKKbeta have different activation requirements.

Q9UQ05	KCNH4_HUMAN	Potassium voltage-gated channel subfamily H member 4	10455180	New ether-a-go-go K+ channel family members localized in human telencephalon.

P32571	UBP4_YEAST	Ubiquitin carboxyl-terminal hydrolase 4	17145966	A conserved late endosome-targeting signal required for Doa4 deubiquitylating enzyme function.

P87262	RL34A_YEAST	60S ribosomal protein L34-A	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q8BQ47	CNPY4_MOUSE	Protein canopy homolog 4	16338228	A molecule that is associated with Toll-like receptor 4 and regulates its cell surface expression.

P54070	KTR6_YEAST	Mannosyltransferase KTR6	9090056	Completion of the Saccharomyces cerevisiae genome sequence allows identification of KTR5, KTR6 and KTR7 and definition of the nine- membered KRE2/MNT1 mannosyltransferase gene family in this organism.

Q05791	CD123_YEAST	Cell division cycle protein 123	15319434	Cdc123 and checkpoint forkhead associated with RING proteins control the cell cycle by controlling eIF2gamma abundance.

Q9JKA9	HCN2_RAT	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2	15265006	Hyperpolarization-activated, cyclic nucleotide-gated HCN2 cation channel forms a protein assembly with multiple neuronal scaffold proteins in distinct modes of protein-protein interaction.

Q9M2J9	BET11_ARATH	Bet1-like SNARE 1-1	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

Q9V3B7	PGSC1_DROME	Peptidoglycan-recognition protein SC1a/b	11106397	A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster.

P92964	RSP31_ARATH	Arginine/serine-rich-splicing factor RSP31	16807317	Phosphoproteomics reveals extensive in vivo phosphorylation of Arabidopsis proteins involved in RNA metabolism.

Q6IMZ0	NFIL3_RAT	Nuclear factor interleukin-3-regulated protein	11262393	Calcium-dependent activation of nuclear factor regulated by interleukin 3/adenovirus E4 promoter-binding protein gene expression by calcineurin/nuclear factor of activated T cells and calcium/calmodulin-dependent protein kinase signaling.

P40383	XRN1_SCHPO	5'-3' exoribonuclease 1	1637812	A single-stranded DNA exonuclease from Schizosaccharomyces pombe.

P87126	CWC2_SCHPO	Pre-mRNA-splicing factor cwc2	10409726	Myb-related fission yeast cdc5p is a component of a 40S snRNP- containing complex and is essential for pre-mRNA splicing.

Q08003	RFU1_YEAST	Regulator of free ubiquitin chains 1	14562095	Global analysis of protein localization in budding yeast.

Q9FMH6	WPP1_ARATH	WPP domain-containing protein 1	15548735	Arabidopsis WPP-domain proteins are developmentally associated with the nuclear envelope and promote cell division.

Q14563	SEM3A_HUMAN	Semaphorin-3A	8269517	The semaphorin genes encode a family of transmembrane and secreted growth cone guidance molecules.

O43278	SPIT1_HUMAN	Kunitz-type protease inhibitor 1	15713485	Conformational lability in serine protease active sites: structures of hepatocyte growth factor activator (HGFA) alone and with the inhibitory domain from HGFA inhibitor-1B.

Q9Y6K9	NEMO_HUMAN	NF-kappa-B essential modulator	14651848	Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress.

Q63622	DLG2_RAT	Disks large homolog 2	8755482	Heteromultimerization and NMDA receptor-clustering activity of Chapsyn-110, a member of the PSD-95 family of proteins.

Q7K480	BN3D1_DROME	Probable methyltransferase bin3	10717484	Identification of Drosophila bicoid-interacting proteins using a custom two-hybrid selection.

Q9JIM4	DUS12_RAT	Dual specificity protein phosphatase 12	10913113	A novel cytosolic dual specificity phosphatase, interacting with glucokinase, increases glucose phosphorylation rate.

O43681	ASNA_HUMAN	ATPase ASNA1	9736449	Dual cytoplasmic and nuclear distribution of the novel arsenite- stimulated human ATPase (hASNA-I).

Q06406	LSM6_YEAST	U6 snRNA-associated Sm-like protein LSm6	10449419	Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6.U5] tri-snRNP.

Q99832	TCPH_HUMAN	T-complex protein 1 subunit eta	9819444	Maturation of human cyclin E requires the function of eukaryotic chaperonin CCT.

P56817	BACE1_HUMAN	Beta-secretase 1	11466313	The transmembrane domain of the Alzheimer's beta-secretase (BACE1) determines its late Golgi localization and access to beta -amyloid precursor protein (APP) substrate.

P09917	LOX5_HUMAN	Arachidonate 5-lipoxygenase	19233132	Distinct parts of leukotriene C(4) synthase interact with 5- lipoxygenase and 5-lipoxygenase activating protein.

P02524	CRBB3_RAT	Beta-crystallin B3	11773034	Lens proteomics: analysis of rat crystallin sequences and two- dimensional electrophoresis map.

Q9Y6A2	CP46A_HUMAN	Cholesterol 24-hydroxylase	10377398	cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain.

Q13492	PICAL_HUMAN	Phosphatidylinositol-binding clathrin assembly protein	10436022	Clathrin assembly lymphoid myeloid leukemia (CALM) protein: localization in endocytic-coated pits, interactions with clathrin, and the impact of overexpression on clathrin-mediated traffic.

O13310	ORB6_SCHPO	Serine/threonine-protein kinase orb6	12456722	Mob2p interacts with the protein kinase Orb6p to promote coordination of cell polarity with cell cycle progression.

O61967	LAP1_CAEEL	Protein lap1	10878806	LET-413 is a basolateral protein required for the assembly of adherens junctions in Caenorhabditis elegans.

Q9NQS1	AVEN_HUMAN	Cell death regulator Aven	10949025	Aven, a novel inhibitor of caspase activation, binds Bcl-xL and Apaf- 1.

Q9QXP0	RHCG_MOUSE	Ammonium transporter Rh type C	16131648	Characterization of ammonia transport by the kidney Rh glycoproteins RhBG and RhCG.

Q9AR07	JMT_ARATH	Jasmonate O-methyltransferase	11287667	Jasmonic acid carboxyl methyltransferase: a key enzyme for jasmonate- regulated plant responses.

Q9UT29	YKGC_SCHPO	Uncharacterized protein C8F11.08c	16169489	Novel genes required for meiotic chromosome segregation are identified by a high-throughput knockout screen in fission yeast.

P35128	UBE2N_DROME	Ubiquitin-conjugating enzyme E2 N	8394720	The Drosophila bendless gene encodes a neural protein related to ubiquitin-conjugating enzymes.

Q76EC5	CHST9_MOUSE	Carbohydrate sulfotransferase 9	12944377	Mouse N-acetylgalactosamine 4-sulfotransferases-1 and -2. Molecular cloning, expression, chromosomal mapping and detection of their activity with GalNAcbeta1-4GlcNAcbeta1-octyl.

Q9M7N6	MAF1_SOLLC	MFP1 attachment factor 1	10488241	MAF1, a novel plant protein interacting with matrix attachment region binding protein MFP1, is located at the nuclear envelope.

Q9D3J8	AMTN_MOUSE	Amelotin	16787391	Cloning of rat amelotin and localization of the protein to the basal lamina of maturation stage ameloblasts and junctional epithelium.

Q55CZ1	GDT2_DICDI	Probable serine/threonine-protein kinase gdt2	15236669	Gdt2 regulates the transition of Dictyostelium cells from growth to differentiation.

P17544	ATF7_HUMAN	Cyclic AMP-dependent transcription factor ATF-7	8288576	ATF-a0, a novel variant of the ATF/CREB transcription factor family, forms a dominant transcription inhibitor in ATF-a heterodimers.

Q6STE5	SMRD3_HUMAN	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3	14701856	Transcription factors and nuclear receptors interact with the SWI/SNF complex through the BAF60c subunit.

Q8NI27	THOC2_HUMAN	THO complex subunit 2	15870275	Human hHpr1/p84/Thoc1 regulates transcriptional elongation and physically links RNA polymerase II and RNA processing factors.

O55034	SPAG4_RAT	Sperm-associated antigen 4 protein	10373309	Spag4, a novel sperm protein, binds outer dense-fiber protein Odf1 and localizes to microtubules of manchette and axoneme.

Q9Y6H8	CXA3_HUMAN	Gap junction alpha-3 protein	10205266	Connexin46 mutations in autosomal dominant congenital cataract.

P52901	ODPA1_ARATH	Pyruvate dehydrogenase E1 component subunit alpha-1, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P38811	TRA1_YEAST	Transcription-associated protein 1	9885573	The ATM-related cofactor Tra1 is a component of the purified SAGA complex.

Q03017	CACT_DROME	NF-kappa-B inhibitor cactus	10636911	Lipopolysaccharide-activated kinase, an essential component for the induction of the antimicrobial peptide genes in Drosophila melanogaster cells.

A3KPE8	SDN1_ARATH	Small RNA degrading nuclease 1	18787168	Degradation of microRNAs by a family of exoribonucleases in Arabidopsis.

P40089	LSM5_YEAST	U6 snRNA-associated Sm-like protein LSm5	10449419	Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6.U5] tri-snRNP.

Q9UTQ4	YL3B_SCHPO	Uncharacterized protein C1071.11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q03981	CSN9_YEAST	COP9 signalosome complex subunit 9	12446563	COP9 signalosome components play a role in the mating pheromone response of S. cerevisiae.

Q10472	GALT1_HUMAN	Polypeptide N-acetylgalactosaminyltransferase 1	9295285	Substrate specificities of three members of the human UDP-N-acetyl- alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase family, GalNAc-T1, -T2, and -T3.

B7ZAQ6	GPHRA_HUMAN	Golgi pH regulator A	12761501	Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.

P02661	CASA1_RAT	Alpha-S1-casein	3952000	Evolution of the casein multigene family: conserved sequences in the 5' flanking and exon regions.

Q9P7D9	RSV1_SCHPO	Zinc finger protein rsv1	9372444	A zinc finger protein required for stationary phase viability in fission yeast.

P33908	MA1A1_HUMAN	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA	8223597	Molecular cloning and primary structure of Man9-mannosidase from human kidney.

Q9QYC3	BHA15_MOUSE	Class A basic helix-loop-helix protein 15	11696558	The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity.

P70166	CPEB1_MOUSE	Cytoplasmic polyadenylation element-binding protein 1	12815066	Regulated CPEB phosphorylation during meiotic progression suggests a mechanism for temporal control of maternal mRNA translation.

P18887	XRCC1_HUMAN	DNA repair protein XRCC1	14755728	Aprataxin, the causative protein for EAOH is a nuclear protein with a potential role as a DNA repair protein.

P53304	SLI1_YEAST	N-acetyltransferase SLI1	15025559	SLI1 (YGR212W) is a major gene conferring resistance to the sphingolipid biosynthesis inhibitor ISP-1, and encodes an ISP-1 N- acetyltransferase in yeast.

Q9UHB4	NDOR1_HUMAN	NADPH-dependent diflavin oxidoreductase 1	15900210	Identification of a functionally impaired allele of human novel oxidoreductase 1 (NDOR1), NDOR1*1.

Q6H3X3	RET1G_HUMAN	Retinoic acid early transcript 1G protein	15240696	Two human ULBP/RAET1 molecules with transmembrane regions are ligands for NKG2D.

Q9ZNZ7	GLTB1_ARATH	Ferredoxin-dependent glutamate synthase 1, chloroplastic	9596633	Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.

P07477	TRY1_HUMAN	Trypsin-1	8841182	Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene.

Q12948	FOXC1_HUMAN	Forkhead box protein C1	7957066	Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending.

P32354	MCM10_YEAST	Minichromosome maintenance protein 10	15494305	Mcm10 regulates the stability and chromatin association of DNA polymerase-alpha.

Q9V6G5	TAZ_DROME	Tafazzin homolog	19164547	Role of calcium-independent phospholipase A2 in the pathogenesis of Barth syndrome.

Q93ZM9	TIF9_ARATH	Protein TIFY 9	17637677	JAZ repressor proteins are targets of the SCF(COI1) complex during jasmonate signalling.

Q12345	IES3_YEAST	Ino eighty subunit 3	12887900	Involvement of actin-related proteins in ATP-dependent chromatin remodeling.

Q9GQF1	JIP3_DROME	JNK-interacting protein 3	11106729	Kinesin-dependent axonal transport is mediated by the Sunday Driver (SYD) protein.

Q7ZXE9	TES_XENLA	Testin	16554046	Tes regulates neural crest migration and axial elongation in Xenopus.

Q08491	SKI7_YEAST	Superkiller protein 7	11532933	Ski7p G protein interacts with the exosome and the Ski complex for 3'-to-5' mRNA decay in yeast.

P40335	VPS26_YEAST	Vacuolar protein sorting-associated protein 26	9700157	A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeast.

O15379	HDAC3_HUMAN	Histone deacetylase 3	11861901	Identification of HDAC10, a novel class II human histone deacetylase containing a leucine-rich domain.

Q6EIG3	CP26B_DANRE	Cytochrome P450 26B1	15661642	Expression of cyp26b1 during zebrafish early development.

Q9P7J2	XLF1_SCHPO	Xrcc4-like factor 1	17151234	Xlf1 is required for DNA repair by nonhomologous end joining in Schizosaccharomyces pombe.

P53927	NOP15_YEAST	Ribosome biogenesis protein 15	11583614	Composition and functional characterization of yeast 66S ribosome assembly intermediates.

P61092	SIA1A_MOUSE	E3 ubiquitin-protein ligase SIAH1A	12646221	Inhibition of ubiquitin ligase Siah-1A by disabled-1.

Q9W358	RIC8_DROME	Synembryn	16228012	Ric-8 controls Drosophila neural progenitor asymmetric division by regulating heterotrimeric G proteins.

P33334	PRP8_YEAST	Pre-mRNA-splicing factor 8	11425851	New roles for the Snp1 and Exo84 proteins in yeast pre-mRNA splicing.

Q0PW40	CRK13_ARATH	Cysteine-rich receptor-like protein kinase 13	17419849	Overexpression of CRK13, an Arabidopsis cysteine-rich receptor-like kinase, results in enhanced resistance to Pseudomonas syringae.

Q8CDG1	PIWL2_MOUSE	Piwi-like protein 2	19114715	MILI, a PIWI-interacting RNA-binding protein, is required for germ Line stem cell self-renewal and appears to positively regulate translation.

P50115	S10A8_RAT	Protein S100-A8	9570842	Identification of posttranslational modifications and cDNA sequencing errors in the rat S100 proteins MRP8 and 14 using electrospray ionization mass spectrometry.

P17799	VIRB9_AGRT5	Protein virB9	2233252	Characterization of the virB operon of an Agrobacterium tumefaciens Ti plasmid: nucleotide sequence and protein analysis.

Q42396	CDPKC_ARATH	Calcium-dependent protein kinase 12	16438971	A novel yeast two-hybrid approach to identify CDPK substrates: characterization of the interaction between AtCPK11 and AtDi19, a nuclear zinc finger protein.

Q9P287	BCCIP_HUMAN	BRCA2 and CDKN1A-interacting protein	10878006	TOK-1, a novel p21Cip1-binding protein that cooperatively enhances p21-dependent inhibitory activity toward CDK2 kinase.

O13705	SEC10_SCHPO	Exocyst complex component sec10	11854409	The multiprotein exocyst complex is essential for cell separation in Schizosaccharomyces pombe.

P70452	STX4_MOUSE	Syntaxin-4	18827011	Murine CENPF interacts with syntaxin 4 in the regulation of vesicular transport.

P49594	FEM2_CAEEL	Ca(2+)/calmodulin-dependent protein kinase phosphatase	17609115	A CUL-2 ubiquitin ligase containing three FEM proteins degrades TRA-1 to regulate C. elegans sex determination.

P33599	NUOCD_ECOLI	NADH-quinone oxidoreductase subunit C/D	11997136	Interaction of purified NDH-1 from Escherichia coli with ubiquinone analogues.

Q08162	RRP44_YEAST	Exosome complex exonuclease DIS3	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Q95ZQ4	AAPK2_CAEEL	5'-AMP-activated protein kinase catalytic subunit alpha-2	15574588	The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans.

P39517	DHH1_YEAST	ATP-dependent RNA helicase DHH1	11780629	The DEAD box helicase, Dhh1p, functions in mRNA decapping and interacts with both the decapping and deadenylase complexes.

P07271	PIF1_YEAST	DNA repair and recombination protein PIF1	8287473	The Saccharomyces PIF1 DNA helicase inhibits telomere elongation and de novo telomere formation.

P84741	PBLFB_EUGGR	Photoactivated adenylate cyclase subunit beta-like protein FB	16121285	Photoactivated adenylyl cyclase (PAC) genes in the flagellate Euglena gracilis mutant strains.

P47001	CIS3_YEAST	Cell wall mannoprotein CIS3	10438739	Identification of two mannoproteins released from cell walls of a Saccharomyces cerevisiae mnn1 mnn9 double mutant by reducing agents.

Q9C5M3	LUP1_ARATH	Lupeol synthase 1	9883589	Cloning and characterization of the Arabidopsis thaliana lupeol synthase gene.

O43038	VPS36_SCHPO	Vacuolar protein-sorting-associated protein 36	17660439	Essential roles of class E Vps proteins for sorting into multivesicular bodies in Schizosaccharomyces pombe.

Q8RWT0	LUP2_ARATH	Lupeol synthase 2	11247608	Molecular cloning and expression in yeast of 2,3-oxidosqualene- triterpenoid cyclases from Arabidopsis thaliana.

Q1ZXD3	PSMD3_DICDI	26S proteasome non-ATPase regulatory subunit 3	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

P61201	CSN2_HUMAN	COP9 signalosome complex subunit 2	7776974	Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor.

P07257	QCR2_YEAST	Cytochrome b-c1 complex subunit 2, mitochondrial	11502169	Yeast mitochondrial dehydrogenases are associated in a supramolecular complex.

O22059	CPC_ARATH	Transcription factor CPC	16291794	Cell-to-cell movement of the CAPRICE protein in Arabidopsis root epidermal cell differentiation.

Q9FT70	RQL4B_ARATH	ATP-dependent DNA helicase Q-like 4B	18000056	Two closely related RecQ helicases have antagonistic roles in homologous recombination and DNA repair in Arabidopsis thaliana.

P63164	RSMN_RAT	Small nuclear ribonucleoprotein-associated protein N	2532363	Isolation of cDNA clones encoding small nuclear ribonucleoparticle- associated proteins with different tissue specificities.

Q9HBH0	RHOF_HUMAN	Rho-related GTP-binding protein RhoF	11084341	The novel Rho-family GTPase rif regulates coordinated actin-based membrane rearrangements.

Q9UDY4	DNJB4_HUMAN	DnaJ homolog subfamily B member 4	9546042	Isolation of a new member of DnaJ-like heat shock protein 40 (Hsp40) from human liver.

P04432	KV124_HUMAN	Ig kappa chain V-I region Daudi	6091049	Immunoglobulin genes of the kappa light chain type from two human lymphoid cell lines are closely related.

Q14141	SEPT6_HUMAN	Septin-6	18047794	SEPT12 interacts with SEPT6 and this interaction alters the filament structure of SEPT6 in Hela cells.

O00483	NDUA4_HUMAN	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4	9352085	Cloning of the human cDNA sequence encoding the NADH:ubiquinone oxidoreductase MLRQ subunit.

Q9GTN7	TAGA_DICDI	Serine protease/ABC transporter B family protein tagA	12756178	TagA, a putative serine protease/ABC transporter of Dictyostelium that is required for cell fate determination at the onset of development.

Q0VIA1	MED10_DANRE	Mediator of RNA polymerase II transcription subunit 10	17208216	Depletion of Med10 enhances Wnt and suppresses Nodal signaling during zebrafish embryogenesis.

Q86KR9	P4HA_DICDI	Prolyl 4-hydroxylase subunit alpha	15705570	The Skp1 prolyl hydroxylase from Dictyostelium is related to the hypoxia-inducible factor-alpha class of animal prolyl 4- hydroxylases.

A6NCS4	NKX26_HUMAN	Homeobox protein Nkx-2.6	15649947	Common arterial trunk associated with a homeodomain mutation of NKX2.6.

O60566	BUB1B_HUMAN	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta	16760428	Phosphorylation- and polo-box-dependent binding of Plk1 to Bub1 is required for the kinetochore localization of Plk1.

P0A7J0	RIBB_ECOLI	3,4-dihydroxy-2-butanone 4-phosphate synthase	1597419	Biosynthesis of riboflavin: cloning, sequencing, and expression of the gene coding for 3,4-dihydroxy-2-butanone 4-phosphate synthase of Escherichia coli.

Q9P7K2	YJN3_SCHPO	Uncharacterized protein C24B10.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P34233	ASH1_YEAST	Transcriptional regulatory protein ASH1	8625409	Identification of asymmetrically localized determinant, Ash1p, required for lineage-specific transcription of the yeast HO gene.

P53923	CTU2_YEAST	Cytoplasmic tRNA 2-thiolation protein 2	14562095	Global analysis of protein localization in budding yeast.

P17608	RYH1_SCHPO	GTP-binding protein ryh1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8BKG3	PTK7_MOUSE	Tyrosine-protein kinase-like 7	15019986	Cloning and characterization of the full-length mouse Ptk7 cDNA encoding a defective receptor protein tyrosine kinase.

Q61191	HCFC1_MOUSE	Host cell factor 1	9334261	The mouse homologue of the human transcription factor C1 (host cell factor). Conservation of forms and function.

P83667	DRTI_DELRE	Kunitz-type serine protease inhibitor DrTI	11397427	Primary sequence determination of a Kunitz inhibitor isolated from Delonix regia seeds.

Q15560	TCEA2_HUMAN	Transcription elongation factor A protein 2	8566795	Isolation and characterization of a cDNA encoding a new type of human transcription elongation factor S-II.

Q55BD5	CSN7_DICDI	COP9 signalosome complex subunit 7	16781008	The COP9 signalosome regulates cell proliferation of Dictyostelium discoideum.

P52890	ATF1_SCHPO	Transcription factor atf1	8557039	Schizosaccharomyces pombe atf1+ encodes a transcription factor required for sexual development and entry into stationary phase.

Q9JJZ5	EGFL6_MOUSE	Epidermal growth factor-like protein 6	18757743	Transcriptome-based systematic identification of extracellular matrix proteins.

Q94AG2	SERK1_ARATH	Somatic embryogenesis receptor kinase 1	15592873	The Arabidopsis SERK1 protein interacts with the AAA-ATPase AtCDC48, the 14-3-3 protein GF14lambda and the PP2C phosphatase KAPP.

Q75I93	BGL07_ORYSJ	Beta-glucosidase 7	18308333	Structural insights into rice BGlu1 beta-glucosidase oligosaccharide hydrolysis and transglycosylation.

Q03067	SGF11_YEAST	SAGA-associated factor 11	15282323	Cluster analysis of mass spectrometry data reveals a novel component of SAGA.

Q9P7Y3	PKR1_SCHPO	V-type ATPase assembly factor pkr1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P16036	MPCP_RAT	Phosphate carrier protein, mitochondrial	2670944	Energy-linked anion transport. Cloning, sequencing, and characterization of a full length cDNA encoding the rat liver mitochondrial proton/phosphate symporter.

Q9UBM7	DHCR7_HUMAN	7-dehydrocholesterol reductase	9465114	Molecular cloning and expression of the human delta7-sterol reductase.

Q03010	UME1_YEAST	Transcriptional regulatory protein UME1	9234739	Characterization of the Wtm proteins, a novel family of Saccharomyces cerevisiae transcriptional modulators with roles in meiotic regulation and silencing.

P08630	BTKL_DROME	Tyrosine-protein kinase Btk29A	9655810	Src64 is required for ovarian ring canal morphogenesis during Drosophila oogenesis.

P12319	FCERA_HUMAN	High affinity immunoglobulin epsilon receptor subunit alpha	2964640	Human and rat mast cell high-affinity immunoglobulin E receptors: characterization of putative alpha-chain gene products.

Q9HGK9	YHLD_SCHPO	Uncharacterized protein C800.13	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P35240	MERL_HUMAN	Merlin	20159598	Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded.

Q9ERI2	RB27A_MOUSE	Ras-related protein Rab-27A	18354201	Doc2 alpha and Munc13-4 regulate Ca(2+) -dependent secretory lysosome exocytosis in mast cells.

P53276	UTP8_YEAST	U3 small nucleolar RNA-associated protein 8	15489292	RNA polymerase I transcription and pre-rRNA processing are linked by specific SSU processome components.

P50502	F10A1_HUMAN	Hsc70-interacting protein	8721986	Molecular cloning of human p48, a transient component of progesterone receptor complexes and an Hsp70-binding protein.

O14599	VCY2_HUMAN	Testis-specific basic protein Y 2	14627543	Identification and characterization of a VCY2 interacting protein-1; VCY2IP-1, a MAP-like protein.

Q9P0T7	TMEM9_HUMAN	Transmembrane protein 9	12359240	Characterization of the novel human transmembrane protein 9 (TMEM9) that localizes to lysosomes and late endosomes.

O43921	EFNA2_HUMAN	Ephrin-A2	9826538	Cloning, chromosal mapping, and tissue expression of the gene encoding the human Eph-family kinase ligand ephrin-A2.

Q7DM58	AB4C_ARATH	ABC transporter C family member 4	16618929	Mapping the Arabidopsis organelle proteome.

P17629	HPR1_YEAST	THO complex subunit HPR1	11060033	A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae.

O15440	MRP5_HUMAN	Multidrug resistance-associated protein 5	9325169	cDNA cloning of a short type of multidrug resistance protein homologue, SMRP, from a human lung cancer cell line.

P01584	IL1B_HUMAN	Interleukin-1 beta	2989698	Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs.

Q9FTA2	TCP21_ARATH	Transcription factor TCP21	19286557	A functional genomics approach reveals CHE as a component of the Arabidopsis circadian clock.

P32502	EI2BB_YEAST	Translation initiation factor eIF-2B subunit beta	8441423	Evidence that GCD6 and GCD7, translational regulators of GCN4, are subunits of the guanine nucleotide exchange factor for eIF-2 in Saccharomyces cerevisiae.

Q09884	DCR1_SCHPO	Protein Dicer	12193640	Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi.

O95970	LGI1_HUMAN	Leucine-rich glioma-inactivated protein 1	17067999	The epilepsy gene LGI1 encodes a secreted glycoprotein that binds to the cell surface.

Q8AV66	TBX6_XENLA	T-box transcription factor TBX6	17577580	Bowline mediates association of the transcriptional corepressor XGrg- 4 with Tbx6 during somitogenesis in Xenopus.

Q8NCC3	PAG15_HUMAN	Group XV phospholipase A2	10092508	Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.

Q43125	CRY1_ARATH	Cryptochrome-1	16093319	A role for Arabidopsis cryptochromes and COP1 in the regulation of stomatal opening.

Q8VYI9	NLTL5_ARATH	Non-specific lipid-transfer protein-like protein At5g64080	14517339	Proteomic analysis of glycosylphosphatidylinositol-anchored membrane proteins.

Q03001	BPA1_HUMAN	Bullous pemphigoid antigen 1	2461961	Isolation of complementary DNA for bullous pemphigoid antigen by use of patients' autoantibodies.

P70062	T7L1A_XENLA	Transcription factor 7-like 1-A	9783587	The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors.

O76464	NFT1_DROME	Nitrilase and fragile histidine triad fusion protein NitFhit	9671749	Nitrilase and Fhit homologs are encoded as fusion proteins in Drosophila melanogaster and Caenorhabditis elegans.

Q6P1N0	C2D1A_HUMAN	Coiled-coil and C2 domain-containing protein 1A	12761501	Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.

P42530	DIS2_DICDI	Discoidin-2	18384150	Structure determination of Discoidin II from Dictyostelium discoideum and carbohydrate binding properties of the lectin domain.

Q8WVM7	STAG1_HUMAN	Cohesin subunit SA-1	9305759	SA-1, a nuclear protein encoded by one member of a novel gene family: molecular cloning and detection in hemopoietic organs.

Q99NG0	ARIP4_MOUSE	Helicase ARIP4	15199138	Dyrk1A potentiates steroid hormone-induced transcription via the chromatin remodeling factor Arip4.

Q10447	PPK2_SCHPO	Protein kinase domain-containing protein ppk2	15821139	Systematic deletion analysis of fission yeast protein kinases.

P05453	ERF3_YEAST	Eukaryotic peptide chain release factor GTP-binding subunit	12923185	Translation termination factor eRF3 mediates mRNA decay through the regulation of deadenylation.

Q685J3	MUC17_HUMAN	Mucin-17	9299468	Molecular cloning of human MUC3 cDNA reveals a novel 59 amino acid tandem repeat region.

O95150	TNF15_HUMAN	Tumor necrosis factor ligand superfamily member 15	9434163	Characterization of a novel TNF-like ligand and recently described TNF ligand and TNF receptor superfamily genes and their constitutive and inducible expression in hematopoietic and non-hematopoietic cells.

Q5ATC7	PLYH_EMENI	Pectate lyase H	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

Q9QWI6	SRCN1_MOUSE	SRC kinase signaling inhibitor 1	14657239	p130Cas-associated protein (p140Cap) as a new tyrosine-phosphorylated protein involved in cell spreading.

Q8NC51	PAIRB_HUMAN	Plasminogen activator inhibitor 1 RNA-binding protein	11001948	Identification and cDNA cloning of a novel RNA-binding protein that interacts with the cyclic nucleotide-responsive sequence in the type-1 plasminogen activator inhibitor mRNA.

Q99956	DUS9_HUMAN	Dual specificity protein phosphatase 9	9030581	Molecular cloning and functional characterization of a novel mitogen- activated protein kinase phosphatase, MKP-4.

P33032	MC5R_HUMAN	Melanocortin receptor 5	7739752	Cloning, expression, and tissue distribution of a fifth melanocortin receptor subtype.

Q9ULA0	DNPEP_HUMAN	Aspartyl aminopeptidase	9632644	Purification, characterization, and cloning of a cytosolic aspartyl aminopeptidase.

O15164	TIF1A_HUMAN	Transcription intermediary factor 1-alpha	9115274	Differential interaction of nuclear receptors with the putative human transcriptional coactivator hTIF1.

Q9SRX9	BAH1_ARATH	E3 ubiquitin-protein ligase BAH1	17355433	A mutation in NLA, which encodes a RING-type ubiquitin ligase, disrupts the adaptability of Arabidopsis to nitrogen limitation.

Q50756	HDRA_METTM	CoB--CoM heterodisulfide reductase iron-sulfur subunit A	2121478	Purification and properties of heterodisulfide reductase from Methanobacterium thermoautotrophicum (strain Marburg).

Q13253	NOGG_HUMAN	Noggin	10080184	Heterozygous mutations in the gene encoding noggin affect human joint morphogenesis.

P04181	OAT_HUMAN	Ornithine aminotransferase, mitochondrial	3456579	Molecular cloning of human ornithine aminotransferase mRNA.

Q12904	AIMP1_HUMAN	Aminoacyl tRNA synthase complex-interacting multifunctional protein 1	14500886	Isolation and characterization of human nuclear and cytosolic multisynthetase complexes and the intracellular distribution of p43/EMAPII.

Q9U969	SWS_DROME	Neuropathy target esterase sws	18945896	Swiss cheese, a protein involved in progressive neurodegeneration, acts as a noncanonical regulatory subunit for PKA-C3.

Q01151	CD83_HUMAN	CD83 antigen	1378080	A novel cell-surface molecule expressed by human interdigitating reticulum cells, Langerhans cells, and activated lymphocytes is a new member of the Ig superfamily.

P19456	PMA2_ARATH	ATPase 2, plasma membrane-type	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P49257	LMAN1_HUMAN	Protein ERGIC-53	7876089	ERGIC-53, a membrane protein of the endoplasmic reticulum-Golgi intermediate compartment, is identical to MR60, an intracellular mannose-specific lectin of myelomonocytic cells.

P69212	MDTJ_ECOLI	Spermidine export protein mdtJ	18039771	Identification of a spermidine excretion protein complex (MdtJI) in Escherichia coli.

P26842	CD27_HUMAN	CD27 antigen	9692890	The TNF receptor family member CD27 signals to Jun N-terminal kinase via Traf-2.

P53867	ATG4_YEAST	Cysteine protease ATG4	9649430	Aut2p and Aut7p, two novel microtubule-associated proteins are essential for delivery of autophagic vesicles to the vacuole.

P50583	AP4A_HUMAN	Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]	7487923	Human diadenosine 5',5''-P1,P4-tetraphosphate pyrophosphohydrolase is a member of the MutT family of nucleotide pyrophosphatases.

Q64346	DUS6_RAT	Dual specificity protein phosphatase 6	8631996	A novel cytoplasmic dual specificity protein tyrosine phosphatase implicated in muscle and neuronal differentiation.

Q8C142	ARH_MOUSE	Low density lipoprotein receptor adapter protein 1	12746448	Normal sorting but defective endocytosis of the low density lipoprotein receptor in mice with autosomal recessive hypercholesterolemia.

Q08774	YO305_YEAST	Uncharacterized protein YOR305W, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

O94684	TFB3_SCHPO	RNA polymerase II transcription factor B subunit 3	14534314	Mediator influences Schizosaccharomyces pombe RNA polymerase II- dependent transcription in vitro.

P20058	HEMO_RABIT	Hemopexin	10504726	Crystal structure of hemopexin reveals a novel high-affinity heme site formed between two beta-propeller domains.

Q9VQS6	DRM_DROME	Protein drumstick	14568103	The Drm-Bowl-Lin relief-of-repression hierarchy controls fore- and hindgut patterning and morphogenesis.

P32754	HPPD_HUMAN	4-hydroxyphenylpyruvate dioxygenase	10942115	Mutations in the 4-hydroxyphenylpyruvate dioxygenase gene (HPD) in patients with tyrosinemia type III.

Q9Y463	DYR1B_HUMAN	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	11980910	Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha.

P05181	CP2E1_HUMAN	Cytochrome P450 2E1	18818195	Structures of human cytochrome P-450 2E1. Insights into the binding of inhibitors and both small molecular weight and fatty acid substrates.

P24388	CRHBP_RAT	Corticotropin-releasing factor-binding protein	1846945	Cloning and characterization of the cDNAs for human and rat corticotropin releasing factor-binding proteins.

P52952	NKX25_HUMAN	Homeobox protein Nkx-2.5	9651244	Congenital heart disease caused by mutations in the transcription factor NKX2-5.

Q5EBH1	RASF5_MOUSE	Ras association domain-containing protein 5	18596699	Novel type of Ras effector interaction established between tumour suppressor NORE1A and Ras switch II.

Q6AZ54	HEMGN_RAT	Hemogen	11161722	A new protein expressed in bone marrow cells and osteoblasts with implication in osteoblast recruitment.

P55774	CCL18_HUMAN	C-C motif chemokine 18	9192897	A dendritic-cell-derived C-C chemokine that preferentially attracts naive T cells.

Q8TBZ2	MYBPP_HUMAN	MYCBP-associated protein	12151104	AMAP-1, a novel testis-specific AMY-1-binding protein, is differentially expressed during the course of spermatogenesis.

P75782	RLMF_ECOLI	Ribosomal RNA large subunit methyltransferase F	18021804	The ybiN gene of Escherichia coli encodes adenine-N6 methyltransferase specific for modification of A1618 of 23 S ribosomal RNA, a methylated residue located close to the ribosomal exit tunnel.

P60604	UB2G2_HUMAN	Ubiquitin-conjugating enzyme E2 G2	20061386	The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.

Q9NRI5	DISC1_HUMAN	Disrupted in schizophrenia 1 protein	18955030	DISC1-kendrin interaction is involved in centrosomal microtubule network formation.

O76360	EGL4_CAEEL	cGMP-dependent protein kinase egl-4	10978280	egl-4 acts through a transforming growth factor-beta/SMAD pathway in Caenorhabditis elegans to regulate multiple neuronal circuits in response to sensory cues.

Q63467	TFF1_RAT	Trefoil factor 1	8836141	cDNA cloning of rat pS2 peptide and expression of trefoil peptides in acetic acid-induced colitis.

P32929	CGL_HUMAN	Cystathionine gamma-lyase	10212249	Kinetics and inhibition of recombinant human cystathionine gamma- lyase. Toward the rational control of transsulfuration.

P38813	BIG1_YEAST	Protein BIG1	12112232	Saccharomyces cerevisiae Big1p, a putative endoplasmic reticulum membrane protein required for normal levels of cell wall beta-1,6- glucan.

Q9JHW4	SELB_MOUSE	Selenocysteine-specific elongation factor	11265756	Decoding apparatus for eukaryotic selenocysteine insertion.

Q15554	TERF2_HUMAN	Telomeric repeat-binding factor 2	16166375	Shelterin: the protein complex that shapes and safeguards human telomeres.

P32198	CPT1A_RAT	Carnitine O-palmitoyltransferase 1, liver isoform	12499375	Identification of conserved amino acid residues in rat liver carnitine palmitoyltransferase I critical for malonyl-CoA inhibition. Mutation of methionine 593 abolishes malonyl-CoA inhibition.

Q9Y314	NOSIP_HUMAN	Nitric oxide synthase-interacting protein	15548660	Nitric oxide synthase (NOS)-interacting protein interacts with neuronal NOS and regulates its distribution and activity.

P62249	RS16_HUMAN	40S ribosomal protein S16	2016298	Molecular cloning and sequence analysis of the human ribosomal protein S16.

Q99523	SORT_HUMAN	Sortilin	14985763	Sortilin is essential for proNGF-induced neuronal cell death.

Q9R049	AMFR_MOUSE	E3 ubiquitin-protein ligase AMFR	10456327	The autocrine motility factor receptor gene encodes a novel type of seven transmembrane protein.

Q10477	MED27_SCHPO	Mediator of RNA polymerase II transcription subunit 27	10625684	Purification and characterization of RNA polymerase II holoenzyme from Schizosaccharomyces pombe.

Q9HB20	PKHA3_HUMAN	Pleckstrin homology domain-containing family A member 3	11001876	Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities.

Q63688	CP7B1_RAT	25-hydroxycholesterol 7-alpha-hydroxylase	12759897	Regulation of oxysterol 7alpha-hydroxylase (CYP7B1) in the rat.

Q13283	G3BP1_HUMAN	Ras GTPase-activating protein-binding protein 1	8649363	A Ras-GTPase-activating protein SH3-domain-binding protein.

O00442	RTC1_HUMAN	RNA 3'-terminal phosphate cyclase	9184239	The human RNA 3'-terminal phosphate cyclase is a member of a new family of proteins conserved in Eucarya, Bacteria and Archaea.

Q9C110	MU177_SCHPO	Meiotically up-regulated gene 177 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P13864	DNMT1_MOUSE	DNA (cytosine-5)-methyltransferase 1	11399088	The activity of the murine DNA methyltransferase Dnmt1 is controlled by interaction of the catalytic domain with the N-terminal part of the enzyme leading to an allosteric activation of the enzyme after binding to methylated DNA.

P53396	ACLY_HUMAN	ATP-citrate synthase	1371749	Cloning and expression of a human ATP-citrate lyase cDNA.

O94572	YGDF_SCHPO	Uncharacterized transporter C1773.15	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8T662	ASNA_DICDI	ATPase ASNA1 homolog	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P86148	RBP1_PLAF7	Reticulocyte-binding protein PFD0110w	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

P48603	CAPZB_DROME	F-actin-capping protein subunit beta	8682865	Actin organization, bristle morphology, and viability are affected by actin capping protein mutations in Drosophila.

P30556	AGTR1_HUMAN	Type-1 angiotensin II receptor	8135787	Novel subtype of human angiotensin II type 1 receptor: cDNA cloning and expression.

Q9C0C4	SEM4C_HUMAN	Semaphorin-4C	17498836	Sema4C participates in myogenic differentiation in vivo and in vitro through the p38 MAPK pathway.

Q9LZA4	PMT7_ARATH	Probable methyltransferase PMT7	16618929	Mapping the Arabidopsis organelle proteome.

P17707	DCAM_HUMAN	S-adenosylmethionine decarboxylase proenzyme	11583147	The structural basis for substrate specificity and inhibition of human S-adenosylmethionine decarboxylase.

Q84Q77	HS17A_ORYSJ	17.9 kDa class I heat shock protein	19703271	Rice sHsp genes: genomic organization and expression profiling under stress and development.

Q8CCI5	RYBP_MOUSE	RING1 and YY1-binding protein	10369680	RYBP, a new repressor protein that interacts with components of the mammalian Polycomb complex, and with the transcription factor YY1.

Q17TI5	BRX_ARATH	Protein BREVIS RADIX	16514016	Characterization of the plant-specific BREVIS RADIX gene family reveals limited genetic redundancy despite high sequence conservation.

P47141	RT26_YEAST	37S ribosomal protein S26, mitochondrial	11278769	Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues.

P40208	GID8_YEAST	Glucose-induced degradation protein 8	14562095	Global analysis of protein localization in budding yeast.

Q96BK5	PINX1_HUMAN	PIN2/TERF1-interacting telomerase inhibitor 1	11003615	Identification of the gene for a novel liver-related putative tumor suppressor at a high-frequency loss of heterozygosity region of chromosome 8p23 in human hepatocellular carcinoma.

Q9W0S9	DIP2_DROME	Disco-interacting protein 2	12137943	Cloning, genomic organization and expression pattern of a novel Drosophila gene, the disco-interacting protein 2 (dip2), and its murine homolog.

P34563	IF5A1_CAEEL	Eukaryotic translation initiation factor 5A-1	15003625	The Caenorhabditis elegans eukaryotic initiation factor 5A homologue, IFF-1, is required for germ cell proliferation, gametogenesis and localization of the P-granule component PGL-1.

P91793	DEFA_AEDAE	Defensin-A	8814787	Cloning and characterization of cDNAs encoding the antibacterial peptide, defensin A, from the mosquito, Aedes aegypti.

P36915	GNL1_HUMAN	Guanine nucleotide-binding protein-like 1	8180467	Structure and evolution of a member of a new subfamily of GTP-binding proteins mapping to the human MHC class I region.

P60664	HIS6_ECOLI	Imidazole glycerol phosphate synthase subunit hisF	8494895	Imidazole glycerol phosphate synthase: the glutamine amidotransferase in histidine biosynthesis.

Q10274	MU152_SCHPO	Meiotically up-regulated gene 152 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O60884	DNJA2_HUMAN	DnaJ homolog subfamily A member 2	9383053	Human CPR (cell cycle progression restoration) genes impart a Far- phenotype on yeast cells.

O08835	SYT11_RAT	Synaptotagmin-11	9162066	The evolutionary pressure to inactivate. A subclass of synaptotagmins with an amino acid substitution that abolishes Ca2+ binding.

Q9UKW4	VAV3_HUMAN	Guanine nucleotide exchange factor VAV3	10523675	Biological and regulatory properties of Vav-3, a new member of the Vav family of oncoproteins.

Q9BPX1	DHB14_HUMAN	17-beta-hydroxysteroid dehydrogenase 14	17067289	Structural and biochemical characterization of human orphan DHRS10 reveals a novel cytosolic enzyme with steroid dehydrogenase activity.

Q8WVX9	FACR1_HUMAN	Fatty acyl-CoA reductase 1	15220348	Mammalian wax biosynthesis: I. Identification of two fatty acyl- coenzyme A reductases with different substrate specificities and tissue distributions.

P38427	TSL1_YEAST	Trehalose synthase complex regulatory subunit TSL1	9194697	Structural analysis of the subunits of the trehalose-6-phosphate synthase/phosphatase complex in Saccharomyces cerevisiae and their function during heat shock.

P14091	CATE_HUMAN	Cathepsin E	7789521	Monomeric human cathepsin E.

Q9NS66	GP173_HUMAN	Probable G-protein coupled receptor 173	10833454	An evolutionarily conserved G-protein coupled receptor family, SREB, expressed in the central nervous system.

P38319	TYDP1_YEAST	Tyrosyl-DNA phosphodiesterase 1	12206772	Genome-wide nuclear morphology screen identifies novel genes involved in nuclear architecture and gene-silencing in Saccharomyces cerevisiae.

P53199	ERG26_YEAST	Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating	12119386	Protein-protein interactions among C-4 demethylation enzymes involved in yeast sterol biosynthesis.

P20042	IF2B_HUMAN	Eukaryotic translation initiation factor 2 subunit 2	3044606	Structure of the beta subunit of translational initiation factor eIF- 2.

P81922	OR47B_DROME	Odorant receptor 47b	10069338	A novel family of divergent seven-transmembrane proteins: candidate odorant receptors in Drosophila.

P83321	FAR6_PENMO	FMRFamide-like neuropeptide FLP6	11959015	Seven novel FMRFamide-like neuropeptide sequences from the eyestalk of the giant tiger prawn Penaeus monodon.

P41811	COPB2_YEAST	Coatomer subunit beta'	17101773	Involvement of specific COPI subunits in protein sorting from the late endosome to the vacuole in yeast.

Q9NQC7	CYLD_HUMAN	Ubiquitin carboxyl-terminal hydrolase CYLD	17495026	The tumor suppressor CYLD regulates entry into mitosis.

O95263	PDE8B_HUMAN	High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B	9784418	Molecular cloning and characterization of human PDE8B, a novel thyroid-specific isozyme of 3',5'-cyclic nucleotide phosphodiesterase.

O00628	PEX7_HUMAN	Peroxisomal targeting signal 2 receptor	9090383	Rhizomelic chondrodysplasia punctata is caused by deficiency of human PEX7, a homologue of the yeast PTS2 receptor.

P27695	APEX1_HUMAN	DNA-(apurinic or apyrimidinic site) lyase	1722334	Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: definition of a family of DNA repair enzymes.

Q9LQK7	AB7I_ARATH	Protein ABCI7, chloroplastic	15184673	AtNAP7 is a plastidic SufC-like ATP-binding cassette/ATPase essential for Arabidopsis embryogenesis.

P38273	CCZ1_YEAST	Vacuolar fusion protein CCZ1	14662743	Yeast homotypic vacuole fusion requires the Ccz1-Mon1 complex during the tethering/docking stage.

P07284	SYSC_YEAST	Seryl-tRNA synthetase, cytoplasmic	3031581	Cloning and characterization of the gene coding for cytoplasmic seryl-tRNA synthetase from Saccharomyces cerevisiae.

Q9S7P9	SNP33_ARATH	SNAP25 homologous protein SNAP33	11591731	Functional characterization of the KNOLLE-interacting t-SNARE AtSNAP33 and its role in plant cytokinesis.

P05129	KPCG_HUMAN	Protein kinase C gamma type	3755548	Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways.

P50528	PLO1_SCHPO	Serine/threonine-protein kinase plo1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Z158	STX17_RAT	Syntaxin-17	9852078	Three novel proteins of the syntaxin/SNAP-25 family.

Q8C551	R51A1_MOUSE	RAD51-associated protein 1	9192668	RAB22 and RAB163/mouse BRCA2: proteins that specifically interact with the RAD51 protein.

O60315	ZEB2_HUMAN	Zinc finger E-box-binding homeobox 2	11279515	Mutations in SIP1, encoding Smad interacting protein 1, cause a form of Hirschsprung disease.

A0MES8	ABI4_ARATH	Ethylene-responsive transcription factor ABI4	17031512	ABI4 mediates the effects of exogenous trehalose on Arabidopsis growth and starch breakdown.

Q9LN63	BZR2_ARATH	Protein BRASSINAZOLE-RESISTANT 2	11970900	Nuclear-localized BZR1 mediates brassinosteroid-induced growth and feedback suppression of brassinosteroid biosynthesis.

Q08345	DDR1_HUMAN	Epithelial discoidin domain-containing receptor 1	8302582	Identification and chromosomal mapping of a receptor tyrosine kinase with a putative phospholipid binding sequence in its ectodomain.

O75871	CEAM4_HUMAN	Carcinoembryonic antigen-related cell adhesion molecule 4	2050678	Molecular cloning of nonspecific cross-reacting antigens in human granulocytes.

Q62417	SRBS1_MOUSE	Sorbin and SH3 domain-containing protein 1	9447983	A novel, multifunctional c-Cbl binding protein in insulin receptor signaling in 3T3-L1 adipocytes.

P49759	CLK1_HUMAN	Dual specificity protein kinase CLK1	1704889	Molecular cloning of a novel human cdc2/CDC28-like protein kinase.

Q8W4E1	RH47_ARATH	DEAD-box ATP-dependent RNA helicase 47, mitochondrial	11874921	Identification of a developmental transition in plasmodesmatal function during embryogenesis in Arabidopsis thaliana.

O60055	UTP20_SCHPO	U3 small nucleolar RNA-associated protein 20	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q7JUY7	CED6_DROME	PTB domain-containing adapter protein ced-6	16772168	Essential role of the apoptotic cell engulfment genes draper and ced- 6 in programmed axon pruning during Drosophila metamorphosis.

Q04201	CUE4_YEAST	CUE domain-containing protein CUE4	14562095	Global analysis of protein localization in budding yeast.

Q9XYP8	GCP3_DROME	Gamma-tubulin complex component 3 homolog	10037793	Characterization of two related Drosophila gamma-tubulin complexes that differ in their ability to nucleate microtubules.

O13992	MUG56_SCHPO	Meiotically up-regulated gene 56 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NPD5	SO1B3_HUMAN	Solute carrier organic anion transporter family member 1B3	10779507	Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide.

Q9H2A9	CHST8_HUMAN	Carbohydrate sulfotransferase 8	11001942	Molecular cloning and characterization of GalNAc 4-sulfotransferase expressed in human pituitary gland.

P04201	MAS_HUMAN	Proto-oncogene Mas	16611642	Up-regulation of the angiotensin II type 1 receptor by the MAS proto- oncogene is due to constitutive activation of Gq/G11 by MAS.

Q9V8R9	41_DROME	Protein 4.1 homolog	8162854	A Drosophila homologue of membrane-skeleton protein 4.1 is associated with septate junctions and is encoded by the coracle gene.

O13547	CCW14_YEAST	Covalently-linked cell wall protein 14	15781460	Comprehensive proteomic analysis of Saccharomyces cerevisiae cell walls: identification of proteins covalently attached via glycosylphosphatidylinositol remnants or mild alkali-sensitive linkages.

P49848	TAF6_HUMAN	Transcription initiation factor TFIID subunit 6	15960975	Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

P20585	MSH3_HUMAN	DNA mismatch repair protein Msh3	11427529	The interaction of DNA mismatch repair proteins with human exonuclease I.

Q9NZK7	PA2GE_HUMAN	Group IIE secretory phospholipase A2	10681567	Structures, enzymatic properties, and expression of novel human and mouse secretory phospholipase A(2)s.

Q86VP6	CAND1_HUMAN	Cullin-associated NEDD8-dissociated protein 1	12504026	CAND1 binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex.

Q92574	TSC1_HUMAN	Hamartin	10585443	Characterization of the cytosolic tuberin-hamartin complex. Tuberin is a cytosolic chaperone for hamartin.

Q15382	RHEB_HUMAN	GTP-binding protein Rheb	8661031	Isolation of cDNA and genomic clones of a human Ras-related GTP- binding protein gene and its chromosomal localization to the long arm of chromosome 7, 7q36.

P58269	DPF3_MOUSE	Zinc finger protein DPF3	17640523	An essential switch in subunit composition of a chromatin remodeling complex during neural development.

Q9Y7Z6	YP02_SCHPO	Meiotic chromosome segregation protein C1539.02	16169489	Novel genes required for meiotic chromosome segregation are identified by a high-throughput knockout screen in fission yeast.

P27695	APEX1_HUMAN	DNA-(apurinic or apyrimidinic site) lyase	12524539	Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A.

O60053	POF12_SCHPO	F-box protein pof12	15147268	Molecular interactions of fission yeast Skp1 and its role in the DNA damage checkpoint.

Q12959	DLG1_HUMAN	Disks large homolog 1	10859302	GAKIN, a novel kinesin-like protein associates with the human homologue of the Drosophila discs large tumor suppressor in T lymphocytes.

Q8BKT2	HES7_MOUSE	Transcription factor HES-7	11260262	Hes7: a bHLH-type repressor gene regulated by Notch and expressed in the presomitic mesoderm.

P36673	TRER_ECOLI	HTH-type transcriptional regulator treR	7608078	Molecular analysis of treB encoding the Escherichia coli enzyme II specific for trehalose.

P39705	NUP60_YEAST	Nucleoporin NUP60	11535617	The nucleoporin Nup60p functions as a Gsp1p-GTP-sensitive tether for Nup2p at the nuclear pore complex.

O59699	YN42_SCHPO	Uncharacterized transporter C36.02c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P60174	TPIS_HUMAN	Triosephosphate isomerase	2876430	Human triose-phosphate isomerase deficiency: a single amino acid substitution results in a thermolabile enzyme.

P34981	TRFR_HUMAN	Thyrotropin-releasing hormone receptor	8395824	Molecular cloning of a functional human thyrotropin-releasing hormone receptor.

O42173	PV1_XENLA	Homeobox protein pv.1	10926781	Xlim-1 and LIM domain binding protein 1 cooperate with various transcription factors in the regulation of the goosecoid promoter.

Q5MJP5	SCX1_ANUPH	Phaiodotoxin	15606762	Phaiodotoxin, a novel structural class of insect-toxin isolated from the venom of the Mexican scorpion Anuroctonus phaiodactylus.

Q05998	THI7_YEAST	Thiamine transporter	9235906	Isolation and characterization of a thiamin transport gene, THI10, from Saccharomyces cerevisiae.

Q90Z06	PRI1A_XENLA	Prickle-like protein 1-A	15854914	Planar cell polarity genes regulate polarized extracellular matrix deposition during frog gastrulation.

P37254	PABS_YEAST	Aminodeoxychorismate synthase	14562095	Global analysis of protein localization in budding yeast.

Q9VPQ6	USH_DROME	Zinc finger protein ush	11404479	The Friend of GATA proteins U-shaped, FOG-1, and FOG-2 function as negative regulators of blood, heart, and eye development in Drosophila.

Q9VD76	GR93A_DROME	Putative gustatory receptor 93a	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

P53894	CBK1_YEAST	Serine/threonine-protein kinase CBK1	12196508	The Saccharomyces cerevisiae Mob2p-Cbk1p kinase complex promotes polarized growth and acts with the mitotic exit network to facilitate daughter cell-specific localization of Ace2p transcription factor.

Q14DK4	GPAT2_MOUSE	Glycerol-3-phosphate acyltransferase 2, mitochondrial	17689486	Cloning and functional characterization of a novel mitochondrial N- ethylmaleimide-sensitive glycerol-3-phosphate acyltransferase (GPAT2).

Q24472	RBF_DROME	Retinoblastoma family protein	8675008	RBF, a novel RB-related gene that regulates E2F activity and interacts with cyclin E in Drosophila.

O75596	CLC3A_HUMAN	C-type lectin domain family 3 member A	10524194	The cartilage-derived, C-type lectin (CLECSF1): structure of the gene and chromosomal location.

Q9LRB0	LCBK1_ARATH	Sphingoid long-chain bases kinase 1	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q6EJB7	SOX3_DANRE	Transcription factor Sox-3	16408288	Comparative genomic and expression analysis of group B1 sox genes in zebrafish indicates their diversification during vertebrate evolution.

Q8TB61	S35B2_HUMAN	Adenosine 3'-phospho 5'-phosphosulfate transporter 1	12761501	Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.

P50454	SERPH_HUMAN	Serpin H1	1309665	Cloning of a human collagen-binding protein, and its homology with rat gp46, chick hsp47 and mouse J6 proteins.

P48994	TRPL_DROME	Transient-receptor-potential-like protein	1314616	Identification of a Drosophila gene encoding a calmodulin-binding protein with homology to the trp phototransduction gene.

Q8W486	Y1491_ARATH	DUF246 domain-containing protein At1g04910	16618929	Mapping the Arabidopsis organelle proteome.

O74531	POF7_SCHPO	F-box protein pof7	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q38845	2AAA_ARATH	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform	12417706	Disruption of a guard cell-expressed protein phosphatase 2A regulatory subunit, RCN1, confers abscisic acid insensitivity in Arabidopsis.

Q9D312	K1C20_MOUSE	Keratin, type I cytoskeletal 20	16608857	Keratin 20 serine 13 phosphorylation is a stress and intestinal goblet cell marker.

Q8BVP1	TRIML_MOUSE	Probable E3 ubiquitin-protein ligase TRIML1	19156909	Characterization and potential function of a novel pre-implantation embryo-specific RING finger protein: TRIML1.

P83578	IKP1_PHYSA	Proteinase inhibitor PSKP-1	15153102	A Kazal prolyl endopeptidase inhibitor isolated from the skin of Phyllomedusa sauvagii.

Q39193	SRK2I_ARATH	Serine/threonine-protein kinase SRK2I	19874541	PYR/PYL/RCAR family members are major in-vivo ABI1 protein phosphatase 2C-interacting proteins in Arabidopsis.

P51115	FXR1A_XENLA	Fragile X mental retardation syndrome-related protein 1 homolog A	7781595	FXR1, an autosomal homolog of the fragile X mental retardation gene.

P40075	SCS2_YEAST	Vesicle-associated membrane protein-associated protein SCS2	9537365	The Saccharomyces cerevisiae SCS2 gene product, a homolog of a synaptobrevin-associated protein, is an integral membrane protein of the endoplasmic reticulum and is required for inositol metabolism.

Q08463	FZD1_RAT	Frizzled-1	1334084	Two homologs of the Drosophila polarity gene frizzled (fz) are widely expressed in mammalian tissues.

P53314	CPD1_YEAST	2',3'-cyclic-nucleotide 3'-phosphodiesterase	10734185	Characterization of the Saccharomyces cerevisiae cyclic nucleotide phosphodiesterase involved in the metabolism of ADP-ribose 1',2'- cyclic phosphate.

P06104	UBC2_YEAST	Ubiquitin-conjugating enzyme E2 2	12226657	RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO.

Q9M9T4	PKS2_ARATH	Protein PHYTOCHROME KINASE SUBSTRATE 2	20071603	The Arabidopsis PHYTOCHROME KINASE SUBSTRATE2 protein is a phototropin signaling element that regulates leaf flattening and leaf positioning.

O54928	SOCS5_MOUSE	Suppressor of cytokine signaling 5	12242343	Expression of the suppressor of cytokine signaling-5 (SOCS5) negatively regulates IL-4-dependent STAT6 activation and Th2 differentiation.

O74977	YQL4_SCHPO	Ankyrin repeat-containing protein C1827.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9R1Q2	CCNL1_RAT	Cyclin-L1	11683997	Dopamine and glutamate induce distinct striatal splice forms of Ania- 6, an RNA polymerase II-associated cyclin.

Q09868	CIP2_SCHPO	RNA-binding post-transcriptional regulator cip2	16407405	Cip1 and Cip2 are novel RNA-recognition-motif proteins that counteract Csx1 function during oxidative stress.

Q04635	ESC1_SCHPO	Protein esc1	8381348	A Schizosaccharomyces pombe gene that promotes sexual differentiation encodes a helix-loop-helix protein with homology to MyoD.

Q9NBD7	CLASP_DROME	CLIP-associating protein	12034769	MAST/Orbit has a role in microtubule-kinetochore attachment and is essential for chromosome alignment and maintenance of spindle bipolarity.

Q8R4D1	SL9A8_MOUSE	Sodium/hydrogen exchanger 8	15522866	Four Na+/H+ exchanger isoforms are distributed to Golgi and post- Golgi Compartments and are involved in organelle pH regulation.

Q54BM7	PPK_DICDI	Polyphosphate kinase	17940044	Polyphosphate kinase 1, a conserved bacterial enzyme, in a eukaryote, Dictyostelium discoideum, with a role in cytokinesis.

P0A7A7	PLSB_ECOLI	Glycerol-3-phosphate acyltransferase	10074094	A missense mutation accounts for the defect in the glycerol-3- phosphate acyltransferase expressed in the plsB26 mutant.

P70581	NUPL1_RAT	Nucleoporin p58/p45	8707840	Molecular and functional characterization of the p62 complex, an assembly of nuclear pore complex glycoproteins.

P46734	MP2K3_HUMAN	Dual specificity mitogen-activated protein kinase kinase 3	7839144	Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms.

O95219	SNX4_HUMAN	Sorting nexin-4	9819414	Identification of a family of sorting nexin molecules and characterization of their association with receptors.

P37685	ALDB_ECOLI	Aldehyde dehydrogenase B	15659684	Isolation and characterization of an aldehyde dehydrogenase encoded by the aldB gene of Escherichia coli.

O35668	HAP1_MOUSE	Huntingtin-associated protein 1	9599014	HAP1-huntingtin interactions do not contribute to the molecular pathology in Huntingtons disease transgenic mice.

Q54JY7	STX7A_DICDI	Syntaxin-7A	10978342	A syntaxin 7 homologue is present in Dictyostelium discoideum endosomes and controls their homotypic fusion.

O42941	CYP7_SCHPO	Peptidylprolyl isomerase cyp7	11884590	Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

Q8TBE0	BAHD1_HUMAN	Bromo adjacent homology domain-containing 1 protein	19666599	Human BAHD1 promotes heterochromatic gene silencing.

P61812	TGFB2_HUMAN	Transforming growth factor beta-2	3322813	Complementary DNA for human glioblastoma-derived T cell suppressor factor, a novel member of the transforming growth factor-beta gene family.

P41838	RAE1_SCHPO	Poly(A)+ RNA export protein	9301023	Advancement through mitosis requires rae1 gene function in fission yeast.

Q9JKP7	DPOE3_MOUSE	DNA polymerase epsilon subunit 3	11000277	Cloning and characterization of the histone-fold proteins YBL1 and YCL1.

P78324	SHPS1_HUMAN	Tyrosine-protein phosphatase non-receptor type substrate 1	9070220	Mouse and human SHPS-1: molecular cloning of cDNAs and chromosomal localization of genes.

O80988	GCSP1_ARATH	Glycine dehydrogenase [decarboxylating] 1, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

O15116	LSM1_HUMAN	U6 snRNA-associated Sm-like protein LSm1	10369684	Sm and Sm-like proteins assemble in two related complexes of deep evolutionary origin.

P05748	RL15A_YEAST	60S ribosomal protein L15-A	6814480	Isolation of seventeen proteins and amino-terminal amino acid sequences of eight proteins from cytoplasmic ribosomes of yeast.

P23977	SC6A3_RAT	Sodium-dependent dopamine transporter	1765147	Cloning and functional characterization of a cocaine-sensitive dopamine transporter.

P61088	UBE2N_HUMAN	Ubiquitin-conjugating enzyme E2 N	19203578	The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage.

Q62388	ATM_MOUSE	Serine-protein kinase ATM	19448632	RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci.

Q9UUK2	GCN5_SCHPO	Histone acetyltransferase gcn5	14988732	Roles of histone acetylation and chromatin remodeling factor in a meiotic recombination hotspot.

O35783	CALU_RAT	Calumenin	15075329	The inhibitory effect of calumenin on the vitamin K-dependent gamma- carboxylation system. Characterization of the system in normal and warfarin-resistant rats.

Q01908	ATPG1_ARATH	ATP synthase gamma chain 1, chloroplastic	1826905	Two genes, atpC1 and atpC2, for the gamma subunit of Arabidopsis thaliana chloroplast ATP synthase.

P43033	LIS1_BOVIN	Platelet-activating factor acetylhydrolase IB subunit alpha	11056532	A role for the lissencephaly gene LIS1 in mitosis and cytoplasmic dynein function.

Q6ER94	BAS1_ORYSJ	2-Cys peroxiredoxin BAS1, chloroplastic	16891402	Rice NTRC is a high-efficiency redox system for chloroplast protection against oxidative damage.

Q92585	MAML1_HUMAN	Mastermind-like protein 1	11390662	A human protein with sequence similarity to Drosophila mastermind coordinates the nuclear form of Notch and a CSL protein to build a transcriptional activator complex on target promoters.

P28161	GSTM2_HUMAN	Glutathione S-transferase Mu 2	2034681	Cloning, expression, and characterization of a class-mu glutathione transferase from human muscle, the product of the GST4 locus.

Q04228	UBX2_YEAST	UBX domain-containing protein 2	16179952	Membrane-bound Ubx2 recruits Cdc48 to ubiquitin ligases and their substrates to ensure efficient ER-associated protein degradation.

Q12421	CIS1_YEAST	Autophagy-related protein 31	17362880	Cis1/Atg31 is required for autophagosome formation in Saccharomyces cerevisiae.

O82798	ARR4_ARATH	Two-component response regulator ARR4	9634588	Two genes with similarity to bacterial response regulators are rapidly and specifically induced by cytokinin in Arabidopsis.

O60870	KIN17_HUMAN	DNA/RNA-binding protein KIN17	12853634	Selective interactions of human kin17 and RPA proteins with chromatin and the nuclear matrix in a DNA damage- and cell cycle-regulated manner.

Q99828	CIB1_HUMAN	Calcium and integrin-binding protein 1	12011095	EDD, the human hyperplastic discs protein, has a role in progesterone receptor coactivation and potential involvement in DNA damage response.

Q8WYH8	ING5_HUMAN	Inhibitor of growth protein 5	12750254	p29ING4 and p28ING5 bind to p53 and p300, and enhance p53 activity.

Q9C9Y6	TRXH9_ARATH	Thioredoxin H9	20133584	A membrane-associated thioredoxin required for plant growth moves from cell to cell, suggestive of a role in intercellular communication.

Q14814	MEF2D_HUMAN	Myocyte-specific enhancer factor 2D	8269842	A fourth human MEF2 transcription factor, hMEF2D, is an early marker of the myogenic lineage.

Q02936	HH_DROME	Protein hedgehog	12586063	Cholesterol modification of hedgehog is required for trafficking and movement, revealing an asymmetric cellular response to hedgehog.

Q05319	STUB_DROME	Serine proteinase stubble	7685111	The Drosophila Stubble-stubbloid gene encodes an apparent transmembrane serine protease required for epithelial morphogenesis.

P22087	FBRL_HUMAN	rRNA 2'-O-methyltransferase fibrillarin	17498821	Human 1A6/DRIM, the homolog of yeast Utp20, functions in the 18S rRNA processing.

P83721	LEC1_CRAMO	Mannose/glucose-specific lectin Cramoll	8579345	Purification of a glucose/mannose specific lectin, isoform 1, from seeds of Cratylia mollis Mart. (Camaratu bean).

Q9V3J3	MS57C_DROME	Accessory gland-specific peptide 57Dc	7711745	Structure and regulation of a gene cluster for male accessory gland transcripts in Drosophila melanogaster.

Q9V5M3	LOLA6_DROME	Longitudinals lacking protein, isoforms N/O/W/X/Y	12538650	A developmentally regulated splice variant from the complex lola locus encoding multiple different zinc finger domain proteins interacts with the chromosomal kinase JIL-1.

Q9LJL3	PREP1_ARATH	Presequence protease 1, chloroplastic/mitochondrial	14617063	Characterization of a novel zinc metalloprotease involved in degrading targeting peptides in mitochondria and chloroplasts.

Q06609	RAD51_HUMAN	DNA repair protein RAD51 homolog 1	18449195	Single-stranded DNA-binding protein hSSB1 is critical for genomic stability.

Q9VC57	ATLAS_DROME	Atlastin	19633650	Homotypic fusion of ER membranes requires the dynamin-like GTPase Atlastin.

Q8I0P1	SPAST_DROME	Spastin	15242610	The hereditary spastic paraplegia gene, spastin, regulates microtubule stability to modulate synaptic structure and function.

P85101	RIPLY_LYCCH	Ribosome-inactivating protein lychnin	2248976	Purification and properties of new ribosome-inactivating proteins with RNA N-glycosidase activity.

P34226	SKT5_YEAST	Protein SKT5	9314530	A septin-based hierarchy of proteins required for localized deposition of chitin in the Saccharomyces cerevisiae cell wall.

Q07798	SPO75_YEAST	Sporulation-specific protein 75	15590821	Morphogenetic pathway of spore wall assembly in Saccharomyces cerevisiae.

P25604	STP22_YEAST	Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease	11511343	Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I.

P83190	PS3_PSEPD	Pseudin-3	11689009	Pseudin-2: an antimicrobial peptide with low hemolytic activity from the skin of the paradoxical frog.

O82660	P2SAF_ARATH	Photosystem II stability/assembly factor HCF136, chloroplastic	11826309	Central functions of the lumenal and peripheral thylakoid proteome of Arabidopsis determined by experimentation and genome-wide prediction.

Q9Y5L0	TNPO3_HUMAN	Transportin-3	10366588	Transportin-SR, a nuclear import receptor for SR proteins.

P42701	I12R1_HUMAN	Interleukin-12 receptor subunit beta-1	7911493	Expression cloning of a human IL-12 receptor component. A new member of the cytokine receptor superfamily with strong homology to gp130.

P50053	KHK_HUMAN	Ketohexokinase	7833921	Molecular basis of essential fructosuria: molecular cloning and mutational analysis of human ketohexokinase (fructokinase).

Q13188	STK3_HUMAN	Serine/threonine-protein kinase 3	16930133	Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled-coil domains, leads to its stabilization and phosphorylation.

C0LGH8	Y1634_ARATH	Probable LRR receptor-like serine/threonine-protein kinase At1g63430	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P32519	ELF1_HUMAN	ETS-related transcription factor Elf-1	1527846	A novel Ets-related transcription factor, Elf-1, binds to human immunodeficiency virus type 2 regulatory elements that are required for inducible trans activation in T cells.

Q9JHU0	DPYL5_RAT	Dihydropyrimidinase-related protein 5	11034345	Ulip6, a novel unc-33 and dihydropyrimidinase related protein highly expressed in developing rat brain.

Q9FZ63	PR1F1_ARATH	PRA1 family protein F1	18583532	The PRA1 gene family in Arabidopsis.

Q5K2P8	POLS2_MOUSE	Polyserase-2	15536082	Human polyserase-2, a novel enzyme with three tandem serine protease domains in a single polypeptide chain.

Q9NUD9	PIGV_HUMAN	GPI mannosyltransferase 2	15623507	PIG-V involved in transferring the second mannose in glycosylphosphatidylinositol.

O00220	TR10A_HUMAN	Tumor necrosis factor receptor superfamily member 10A	9430227	Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway.

O43272	PROD_HUMAN	Proline dehydrogenase, mitochondrial	9305847	A model for p53-induced apoptosis.

Q9UJU6	DBNL_HUMAN	Drebrin-like protein	11689006	Caspase-mediated cleavage of actin-binding and SH3-domain-containing proteins cortactin, HS1, and HIP-55 during apoptosis.

P60164	KA111_PARVI	Potassium channel toxin alpha-KTx 11.1	14561751	A subfamily of acidic alpha-K(+) toxins.

P35240	MERL_HUMAN	Merlin	10861283	The neurofibromatosis 2 tumor suppressor protein interacts with hepatocyte growth factor-regulated tyrosine kinase substrate.

O15392	BIRC5_HUMAN	Baculoviral IAP repeat-containing protein 5	16291752	Molecular analysis of survivin isoforms: evidence that alternatively spliced variants do not play a role in mitosis.

P53840	TOF1_YEAST	Topoisomerase 1-associated factor 1	16137625	Mrc1 and Tof1 promote replication fork progression and recovery independently of Rad53.

P31016	DLG4_RAT	Disks large homolog 4	11502259	Regulation of dendritic spine morphology by SPAR, a PSD-95-associated RapGAP.

P30874	SSR2_HUMAN	Somatostatin receptor type 2	10551867	Somatostatin receptor interacting protein defines a novel family of multidomain proteins present in human and rodent brain.

Q01883	RAG1_ORYSJ	Seed allergenic protein RAG1	1376283	Nucleotide sequence of a cDNA clone encoding a major allergenic protein in rice seeds. Homology of the deduced amino acid sequence with members of alpha-amylase/trypsin inhibitor family.

Q9M0G9	AB24B_ARATH	ABC transporter B family member 24, mitochondrial	17517886	Functional characterization of AtATM1, AtATM2, and AtATM3, a subfamily of Arabidopsis half-molecule ATP-binding cassette transporters implicated in iron homeostasis.

Q9P7M6	YIOC_SCHPO	UPF0663 protein P27G11.12	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P63003	AES_RAT	Amino-terminal enhancer of split	8245004	A rat homolog of the Drosophila enhancer of split (groucho) locus lacking WD-40 repeats.

Q9UUC8	RM51_SCHPO	60S ribosomal protein L51, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P84759	JELL3_APIME	Jellein-3	15203237	Jelleines: a family of antimicrobial peptides from the royal jelly of honeybees (Apis mellifera).

P98081	DAB_DROME	Protein disabled	9671493	Disabled is a putative adaptor protein that functions during signaling by the sevenless receptor tyrosine kinase.

P32901	PTR2_YEAST	Peptide transporter PTR2	8264579	Isolation and characterization of a Saccharomyces cerevisiae peptide transport gene.

Q39250	ADF1_ARATH	Actin-depolymerizing factor 1	11025548	A comparative structural analysis of the ADF/cofilin family.

Q86UL3	GPAT4_HUMAN	Glycerol-3-phosphate acyltransferase 4	18238778	AGPAT6 is a novel microsomal glycerol-3-phosphate acyltransferase.

Q6BF17	DGOD_ECOLI	D-galactonate dehydratase	211976	The utilisation of D-galactonate and D-2-oxo-3-deoxygalactonate by Escherichia coli K-12. Biochemical and genetical studies.

P10912	GHR_HUMAN	Growth hormone receptor	2813379	Characterization of the human growth hormone receptor gene and demonstration of a partial gene deletion in two patients with Laron- type dwarfism.

Q9LHE5	TO401_ARATH	Mitochondrial import receptor subunit TOM40 homolog 1	11161051	Purification and characterization of the preprotein translocase of the outer mitochondrial membrane from Arabidopsis. Identification of multiple forms of TOM20.

P50082	AMA1_YEAST	Meiosis-specific APC/C activator protein AMA1	11114178	Ama1p is a meiosis-specific regulator of the anaphase promoting complex/cyclosome in yeast.

O94921	CDK14_HUMAN	Cell division protein kinase 14	19524571	Cyclin Y, a novel membrane-associated cyclin, interacts with PFTK1.

P63009	AP2B1_BOVIN	AP-2 complex subunit beta	1969413	Conservation and diversity in families of coated vesicle adaptins.

Q9XHP0	11S2_SESIN	11S globulin seed storage protein 2	10606554	Molecular cloning of 11S globulin and 2S albumin, the two major seed storage proteins in sesame.

Q9VXP4	PA1B2_DROME	Platelet-activating factor acetylhydrolase IB subunit beta homolog	10737922	Homologs of the alpha- and beta-subunits of mammalian brain platelet- activating factor acetylhydrolase Ib in the Drosophila melanogaster genome.

P07866	LTE1_YEAST	Guanine nucleotide exchange factor LTE1	10219244	Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex.

Q9SL93	ASK3_ARATH	SKP1-like protein 3	14749489	Expression and interaction analysis of Arabidopsis Skp1-related genes.

Q6DUW9	IDL2_ARATH	Protein IDA-LIKE 2	18660431	The EPIP peptide of INFLORESCENCE DEFICIENT IN ABSCISSION is sufficient to induce abscission in arabidopsis through the receptor- like kinases HAESA and HAESA-LIKE2.

P15565	TRM1_YEAST	N(2),N(2)-dimethylguanosine tRNA methyltransferase, mitochondrial	9801306	Point and deletion mutations eliminate one or both methyl group transfers catalysed by the yeast TRM1 encoded tRNA (m22G26)dimethyltransferase.

Q94AH8	TPS6_ARATH	Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 6	17981987	Trehalose-6-phosphate synthase/phosphatase regulates cell shape and plant architecture in Arabidopsis.

P53218	POP6_YEAST	Ribonucleases P/MRP protein subunit POP6	9620854	Purification and characterization of the nuclear RNase P holoenzyme complex reveals extensive subunit overlap with RNase MRP.

O94294	SOG2_SCHPO	Leucine-rich repeat-containing protein sog2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q01859	ATPBM_ORYSJ	ATP synthase subunit beta, mitochondrial	1387558	Nucleotide sequence of a cDNA encoding a beta subunit of the mitochondrial ATPase from rice (Oryza sativa).

Q13191	CBLB_HUMAN	E3 ubiquitin-protein ligase CBL-B	7784085	Cloning and characterization of cbl-b: a SH3 binding protein with homology to the c-cbl proto-oncogene.

Q12341	HAT1_YEAST	Histone acetyltransferase type B catalytic subunit	8858151	The major cytoplasmic histone acetyltransferase in yeast: links to chromatin replication and histone metabolism.

P78527	PRKDC_HUMAN	DNA-dependent protein kinase catalytic subunit	9442054	DNA-dependent protein kinase interacts with antigen receptor response element binding proteins NF90 and NF45.

Q7G9P4	ALDO3_ARATH	Abscisic-aldehyde oxidase	19309463	Identification of a novel E3 ubiquitin ligase that is required for suppression of premature senescence in Arabidopsis.

Q9R2C1	SERP1_RAT	Stress-associated endoplasmic reticulum protein 1	10469658	Control of glycosylation of MHC class II-associated invariant chain by translocon-associated RAMP4.

P17563	SBP1_MOUSE	Selenium-binding protein 1	2225343	DNA sequencing of a mouse liver protein that binds selenium: implications for selenium's mechanism of action in cancer prevention.

Q5EAK6	ATM_DROME	Serine/threonine-protein kinase ATM	16020777	Drosophila ATM and Mre11 are essential for the G2/M checkpoint induced by low-dose irradiation.

Q8GY31	CDC25_ARATH	Dual specificity phosphatase Cdc25	15336525	Characterization of the Arabidopsis thaliana Arath;CDC25 dual- specificity tyrosine phosphatase.

P01086	IAAE_HORVU	Trypsin inhibitor CMe	12650522	Transgenic expression of trypsin inhibitor CMe from barley in indica and japonica rice, confers resistance to the rice weevil Sitophilus oryzae.

Q9PTS2	DCUP_DANRE	Uroporphyrinogen decarboxylase	9806541	A zebrafish model for hepatoerythropoietic porphyria.

Q62504	MINT_MOUSE	Msx2-interacting protein	10451362	The RRM domain of MINT, a novel msx2 binding protein, recognizes and regulates the rat osteocalcin promoter.

Q99321	DDP1_YEAST	Diphosphoinositol polyphosphate phosphohydrolase DDP1	10419486	The diadenosine hexaphosphate hydrolases from Schizosaccharomyces pombe and Saccharomyces cerevisiae are homologues of the human diphosphoinositol polyphosphate phosphohydrolase. Overlapping substrate specificities in a MutT-type protein.

P21781	FGF7_HUMAN	Keratinocyte growth factor	2475908	Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth.

Q24572	CAF1_DROME	Probable histone-binding protein Caf1	12408863	Drosophila Enhancer of zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites.

Q63344	MOT2_RAT	Monocarboxylate transporter 2	9182702	Cloning of the monocarboxylate transporter isoform MCT2 from rat testis provides evidence that expression in tissues is species- specific and may involve post-transcriptional regulation.

P52910	ACS2_YEAST	Acetyl-coenzyme A synthetase 2	8910545	The two acetyl-coenzyme A synthetases of Saccharomyces cerevisiae differ with respect to kinetic properties and transcriptional regulation.

Q9HB89	NMUR1_HUMAN	Neuromedin-U receptor 1	10899166	Identification and characterization of two neuromedin U receptors differentially expressed in peripheral tissues and the central nervous system.

O60663	LMX1B_HUMAN	LIM homeobox transcription factor 1-beta	9837817	Mutation analysis of LMX1B gene in nail-patella syndrome patients.

Q9NV92	NFIP2_HUMAN	NEDD4 family-interacting protein 2	18776082	Regulation of the divalent metal ion transporter DMT1 and iron homeostasis by a ubiquitin-dependent mechanism involving Ndfips and WWP2.

Q03944	VPS64_YEAST	Vacuolar protein sorting-associated protein 64	12588993	Far3 and five interacting proteins prevent premature recovery from pheromone arrest in the budding yeast Saccharomyces cerevisiae.

Q9UHY7	ENOPH_HUMAN	Enolase-phosphatase E1	15843022	Crystal structure of human E1 enzyme and its complex with a substrate analog reveals the mechanism of its phosphatase/enolase activity.

O95377	CXB5_HUMAN	Gap junction beta-5 protein	9843209	Mutations in the human connexin gene GJB3 cause erythrokeratodermia variabilis.

P07327	ADH1A_HUMAN	Alcohol dehydrogenase 1A	2347582	The human class I alcohol dehydrogenase gene cluster: three genes are tandemly organized in an 80-kb-long segment of the genome.

Q9XFT3	PSBQ1_ARATH	Oxygen-evolving enhancer protein 3-1, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

O48946	CESA1_ARATH	Cellulose synthase A catalytic subunit 1 [UDP-forming]	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q7LGC8	CHST3_HUMAN	Carbohydrate sulfotransferase 3	9883891	Functional expression and genomic structure of human chondroitin 6- sulfotransferase.

P87314	HIR1_SCHPO	Protein hir1	15121850	The Schizosaccharomyces pombe HIRA-like protein Hip1 is required for the periodic expression of histone genes and contributes to the function of complex centromeres.

P22001	KCNA3_HUMAN	Potassium voltage-gated channel subfamily A member 3	1373731	Cloning, functional expression, and regulation of two K+ channels in human T lymphocytes.

Q16587	ZNF74_HUMAN	Zinc finger protein 74	1639391	Cloning of six new genes with zinc finger motifs mapping to short and long arms of human acrocentric chromosome 22 (p and q11.2).

P40339	RFC4_YEAST	Replication factor C subunit 4	12665596	Mechanical link between cohesion establishment and DNA replication: Ctf7p/Eco1p, a cohesion establishment factor, associates with three different replication factor C complexes.

P83572	ARALA_ARAEL	Aralin A chain	12963119	Aralin, a new cytotoxic protein from Aralia elata, inducing apoptosis in human cancer cells.

P47116	PTK2_YEAST	Serine/threonine-protein kinase PTK2/STK2	11003661	Regulation of yeast H(+)-ATPase by protein kinases belonging to a family dedicated to activation of plasma membrane transporters.

Q9ULZ9	MMP17_HUMAN	Matrix metalloproteinase-17	8640782	Molecular cloning of a novel membrane-type matrix metalloproteinase from a human breast carcinoma.

Q9NS18	GLRX2_HUMAN	Glutaredoxin-2, mitochondrial	11397793	Identification and characterization of a new mammalian glutaredoxin (thioltransferase), Grx2.

O74739	PNG1_SCHPO	Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q93ZM9	TIF9_ARATH	Protein TIFY 9	17675405	A downstream mediator in the growth repression limb of the jasmonate pathway.

Q8W206	CSN6A_ARATH	COP9 signalosome complex subunit 6a	12615944	Characterization of the last subunit of the Arabidopsis COP9 signalosome: implications for the overall structure and origin of the complex.

Q26622	SHR2_STRPU	Orphan steroid hormone receptor 2	8806817	A novel sea urchin nuclear receptor encoded by alternatively spliced maternal RNAs.

P98166	VLDLR_RAT	Very low-density lipoprotein receptor	7929362	Regulation of the very low density lipoprotein receptor by thyroid hormone in rat skeletal muscle.

Q04401	ACN9_YEAST	Acetate non-utilizing protein 9, mitochondrial	10103055	Acn9 is a novel protein of gluconeogenesis that is located in the mitochondrial intermembrane space.

Q15291	RBBP5_HUMAN	Retinoblastoma-binding protein 5	17355966	Identification and characterization of the human Set1B histone H3- Lys4 methyltransferase complex.

P13498	CY24A_HUMAN	Cytochrome b-245 light chain	2243141	Human neutrophil cytochrome b light chain (p22-phox). Gene structure, chromosomal location, and mutations in cytochrome-negative autosomal recessive chronic granulomatous disease.

Q60760	GRB10_MOUSE	Growth factor receptor-bound protein 10	9062339	The adapter protein Grb10 associates preferentially with the insulin receptor as compared with the IGF-I receptor in mouse fibroblasts.

Q8CF97	VCIP1_RAT	Deubiquitinating protein VCIP135	12473691	VCIP135, a novel essential factor for p97/p47-mediated membrane fusion, is required for Golgi and ER assembly in vivo.

Q8GZM7	PIF1_ARATH	Transcription factor PIF1	16359394	PIF1 is regulated by light-mediated degradation through the ubiquitin-26S proteasome pathway to optimize photomorphogenesis of seedlings in Arabidopsis.

Q02080	MEF2B_HUMAN	Myocyte-specific enhancer factor 2B	1516833	Human myocyte-specific enhancer factor 2 comprises a group of tissue- restricted MADS box transcription factors.

O82804	ELF3_ARATH	Protein EARLY FLOWERING 3	10571046	Isolation of a gene from Arabidopsis thaliana related to nematode feeding structures.

O43193	MTLR_HUMAN	Motilin receptor	10381885	Receptor for motilin identified in the human gastrointestinal system.

O75529	TAF5L_HUMAN	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L	11564863	Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage- binding factors in vivo.

Q9JLI7	SPAG6_MOUSE	Sperm-associated antigen 6	12167721	Male infertility, impaired sperm motility, and hydrocephalus in mice deficient in sperm-associated antigen 6.

O70441	SYN3_RAT	Synapsin-3	9593663	Synapsin III, a novel synapsin with an unusual regulation by Ca2+.

Q9Z0V5	PRDX4_RAT	Peroxiredoxin-4	10025941	Cloning of the peroxiredoxin gene family in rats and characterization of the fourth member.

Q9Y048	DTN1_CAEEL	Dystrobrevin-1	10369883	Dystrobrevin- and dystrophin-like mutants display similar phenotypes in the nematode Caenorhabditis elegans.

P42844	ZIM17_YEAST	Mitochondrial protein import protein ZIM17	15992824	Inactivation of the mitochondrial heat shock protein Zim17 leads to aggregation of matrix Hsp70s followed by pleiotropic effects on morphology and protein biogenesis.

Q8WV28	BLNK_HUMAN	B-cell linker protein	10583958	An essential role for BLNK in human B cell development.

Q6V0L0	CP26C_HUMAN	Cytochrome P450 26C1	14532297	A novel human cytochrome P450, CYP26C1, involved in metabolism of 9- cis and all-trans isomers of retinoic acid.

Q6TV19	DICER_DANRE	Endoribonuclease Dicer	14528306	The microRNA-producing enzyme Dicer1 is essential for zebrafish development.

Q13889	TF2H3_HUMAN	General transcription factor IIH subunit 3	8194529	p44 and p34 subunits of the BTF2/TFIIH transcription factor have homologies with SSL1, a yeast protein involved in DNA repair.

P37382	RPB3_SCHPO	DNA-directed RNA polymerase II subunit RPB3	8367291	Subunits of the Schizosaccharomyces pombe RNA polymerase II: enzyme purification and structure of the subunit 3 gene.

P40152	YNV7_YEAST	Putative metallophosphoesterase YNL217W	14562095	Global analysis of protein localization in budding yeast.

Q08117	AES_HUMAN	Amino-terminal enhancer of split	10660609	Inhibition of nuclear factor-kappaB-mediated transcription by association with the amino-terminal enhancer of split, a Groucho- related protein lacking WD40 repeats.

Q08986	SAM3_YEAST	S-adenosylmethionine permease SAM3	10497160	Transport of sulfonium compounds. Characterization of the s- adenosylmethionine and s-methylmethionine permeases from the yeast Saccharomyces cerevisiae.

Q9FRV0	CHIC_SECCE	Basic endochitinase C	11999399	Molecular cloning, functional expression, and mutagenesis of cDNA encoding rye (Secale cereale) seed chitinase-c.

Q02783	LPE10_YEAST	Mitochondrial inner membrane magnesium transporter LPE10	11254124	The mitochondrial inner membrane protein Lpe10p, a homologue of Mrs2p, is essential for magnesium homeostasis and group II intron splicing in yeast.

P43005	EAA3_HUMAN	Excitatory amino acid transporter 3	7521911	Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex.

Q8WYH8	ING5_HUMAN	Inhibitor of growth protein 5	18794358	Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexes.

P0AGE4	SSTT_ECOLI	Serine/threonine transporter sstT	12097162	Purification, reconstitution, and characterization of Na(+)/serine symporter, SstT, of Escherichia coli.

P55040	GEM_HUMAN	GTP-binding protein GEM	7912851	Gem: an induced, immediate early protein belonging to the Ras family.

P61204	ARF3_HUMAN	ADP-ribosylation factor 3	1744102	Isolation and characterization of the human gene for ADP-ribosylation factor 3, a 20-kDa guanine nucleotide-binding protein activator of cholera toxin.

P62837	UB2D2_HUMAN	Ubiquitin-conjugating enzyme E2 D2	7724550	Reconstitution of p53-ubiquitinylation reactions from purified components: the role of human ubiquitin-conjugating enzyme UBC4 and E6-associated protein (E6AP).

Q9SLC3	ATL41_ARATH	E3 ubiquitin-protein ligase ATL41	15644464	Functional analysis of the RING-type ubiquitin ligase family of Arabidopsis.

Q9P7T1	SIB1_SCHPO	Hydroxamate-type ferrichrome siderophore peptide synthetase	15689108	Ferrichrome in Schizosaccharomyces pombe -- an iron transport and iron storage compound.

Q9BVM4	A2LD1_HUMAN	Gamma-glutamylaminecyclotransferase	20110353	Identification and characterization of gamma-glutamylamine cyclotransferase, an enzyme responsible for gamma-glutamyl-epsilon- lysine catabolism.

O94360	MOB1_SCHPO	Maintenance of ploidy protein mob1	10769201	The S. pombe orthologue of the S. cerevisiae mob1 gene is essential and functions in signalling the onset of septum formation.

Q04727	TLE4_HUMAN	Transducin-like enhancer protein 4	1303260	Human homologs of a Drosophila enhancer of split gene product define a novel family of nuclear proteins.

P53871	DUG3_YEAST	Probable glutamine amidotransferase DUG3	17179087	The alternative pathway of glutathione degradation is mediated by a novel protein complex involving three new genes in Saccharomyces cerevisiae.

Q9NBD7	CLASP_DROME	CLIP-associating protein	16303556	Length control of the metaphase spindle.

Q9EPK8	TRPV4_MOUSE	Transient receptor potential cation channel subfamily V member 4	11025659	OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity.

P84701	CONO_CONMU	Conophan mus-V	15853325	Polypeptide chains containing D-gamma-hydroxyvaline.

Q29983	MICA_HUMAN	MHC class I polypeptide-related sequence A	10426994	An activating immunoreceptor complex formed by NKG2D and DAP10.

Q9NQ31	BCA3_HUMAN	Proline-rich protein BCA3	15630084	A-kinase-interacting protein localizes protein kinase A in the nucleus.

P05317	RLA0_YEAST	60S acidic ribosomal protein P0	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q9ZS97	AB8I_ARATH	UPF0051 protein ABCI8, chloroplastic	11156608	A plastidic ABC protein involved in intercompartmental communication of light signaling.

O15427	MOT4_HUMAN	Monocarboxylate transporter 4	9425115	Cloning and sequencing of four new mammalian monocarboxylate transporter (MCT) homologues confirms the existence of a transporter family with an ancient past.

Q06817	SYG2_YEAST	Glycyl-tRNA synthetase 2	14562095	Global analysis of protein localization in budding yeast.

Q6NW96	SP9_DANRE	Transcription factor Sp9	15358670	Sp8 and Sp9, two closely related buttonhead-like transcription factors, regulate Fgf8 expression and limb outgrowth in vertebrate embryos.

Q9Y2C5	S17A4_HUMAN	Putative small intestine sodium-dependent phosphate transport protein	10319585	Isolation and chromosomal mapping of a novel human gene showing homology to Na+/PO4 cotransporter.

P31151	S10A7_HUMAN	Protein S100-A7	12421467	RanBPM interacts with psoriasin in vitro and their expression correlates with specific clinical features in vivo in breast cancer.

Q96L58	B3GT6_HUMAN	Beta-1,3-galactosyltransferase 6	11551958	Biosynthesis of the linkage region of glycosaminoglycans: cloning and activity of galactosyltransferase II, the sixth member of the beta 1,3-galactosyltransferase family (beta 3GalT6).

P29029	CHIT_YEAST	Endochitinase	1918080	Chitinase is required for cell separation during growth of Saccharomyces cerevisiae.

P63165	SUMO1_HUMAN	Small ubiquitin-related modifier 1	9019411	A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2.

O43044	NU120_SCHPO	Nucleoporin nup120	15226438	The fission yeast Nup107-120 complex functionally interacts with the small GTPase Ran/Spi1 and is required for mRNA export, nuclear pore distribution, and proper cell division.

Q04836	ROC3_ARATH	31 kDa ribonucleoprotein, chloroplastic	7972518	An Arabidopsis chloroplast RNA-binding protein gene encodes multiple mRNAs with different 5' ends.

P53010	PAN2_YEAST	PAB-dependent poly(A)-specific ribonuclease subunit PAN2	8816488	PAN3 encodes a subunit of the Pab1p-dependent poly(A) nuclease in Saccharomyces cerevisiae.

P34552	ALX1_CAEEL	Apoptosis-linked gene 2-interacting protein X 1	16236769	LIN-12/Notch trafficking and regulation of DSL ligand activity during vulval induction in Caenorhabditis elegans.

Q7TQ20	DNJC2_RAT	DnaJ homolog subfamily C member 2	11289140	Immunization with an antigen identified by cytokine tumor vaccine- assisted SEREX (CAS) suppressed growth of the rat 9L glioma in vivo.

Q9SN27	ATL59_ARATH	E3 ubiquitin-protein ligase ATL59	15644464	Functional analysis of the RING-type ubiquitin ligase family of Arabidopsis.

Q8WXS3	BAALC_HUMAN	Brain and acute leukemia cytoplasmic protein	11707601	BAALC, the human member of a novel mammalian neuroectoderm gene lineage, is implicated in hematopoiesis and acute leukemia.

Q53EK2	NSE1_SCHPO	Non-structural maintenance of chromosomes element 1	15331764	Nse1, Nse2, and a novel subunit of the Smc5-Smc6 complex, Nse3, play a crucial role in meiosis.

O70354	CAH11_MOUSE	Carbonic anhydrase-related protein 11	9878252	Evolutionarily conserved, 'acatalytic' carbonic anhydrase-related protein XI contains a sequence motif present in the neuropeptide sauvagine: the human CA-RP XI gene (CA11) is embedded between the secretor gene cluster and the DBP gene at 19q13.3.

A5PN28	OTO1A_DANRE	Otolin-1-A	15905077	Otolith matrix proteins OMP-1 and Otolin-1 are necessary for normal otolith growth and their correct anchoring onto the sensory maculae.

Q3TCN2	PLBL2_MOUSE	Putative phospholipase B-like 2	17007843	Molecular characterization of the hypothetical 66.3-kDa protein in mouse: lysosomal targeting, glycosylation, processing and tissue distribution.

P93002	NPR1_ARATH	Regulatory protein NPR1	10659709	NPR1 differentially interacts with members of the TGA/OBF family of transcription factors that bind an element of the PR-1 gene required for induction by salicylic acid.

P40452	COA1_YEAST	Cytochrome oxidase assembly protein 1	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q9ZRF9	RPK1_ARATH	Probable LRR receptor-like serine/threonine-protein kinase RPK1	18158146	Two receptor-like kinases required together for the establishment of Arabidopsis cotyledon primordia.

Q7T103	P5F11_XENLA	POU domain, class 5, transcription factor 1.1	15292233	The POU factor Oct-25 regulates the Xvent-2B gene and counteracts terminal differentiation in Xenopus embryos.

Q02383	SEMG2_HUMAN	Semenogelin-2	1517240	Gene structure of semenogelin I and II. The predominant proteins in human semen are encoded by two homologous genes on chromosome 20.

Q9ERZ8	TRPV4_RAT	Transient receptor potential cation channel subfamily V member 4	11081638	Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor.

Q9CR98	F136A_MOUSE	Protein FAM136A	14651853	Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.

Q6AWJ9	PTK7_DROME	Tyrosine-protein kinase-like otk	1371458	Dtrk, a Drosophila gene related to the trk family of neurotrophin receptors, encodes a novel class of neural cell adhesion molecule.

Q9FWS9	BLH3_ARATH	BEL1-like homeodomain protein 3	16513846	Nuclear import of the transcription factor SHOOT MERISTEMLESS depends on heterodimerization with BLH proteins expressed in discrete sub- domains of the shoot apical meristem of Arabidopsis thaliana.

P19538	CI_DROME	Protein cubitus interruptus	16740475	A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor.

O94905	ERLN2_HUMAN	Erlin-2	19240031	An endoplasmic reticulum (ER) membrane complex composed of SPFH1 and SPFH2 mediates the ER-associated degradation of inositol 1,4,5- trisphosphate receptors.

Q9VJS8	ELBOW_DROME	Zinc finger protein Elbow	12117809	Elbow and Noc define a family of zinc finger proteins controlling morphogenesis of specific tracheal branches.

P40337	VHL_HUMAN	Von Hippel-Lindau disease tumor suppressor	7660130	Binding of the von Hippel-Lindau tumor suppressor protein to Elongin B and C.

O15162	PLS1_HUMAN	Phospholipid scramblase 1	9218461	Molecular cloning of human plasma membrane phospholipid scramblase. A protein mediating transbilayer movement of plasma membrane phospholipids.

Q86XK2	FBX11_HUMAN	F-box only protein 11	10531037	A family of mammalian F-box proteins.

Q9NSA3	CNBP1_HUMAN	Beta-catenin-interacting protein 1	12408825	ICAT inhibits beta-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300 using independent structural modules.

Q9UT17	YFYB_SCHPO	Uncharacterized protein C9.11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P30988	CALCR_HUMAN	Calcitonin receptor	7588285	Molecular cloning and functional expression of a third isoform of the human calcitonin receptor and partial characterization of the calcitonin receptor gene.

Q60755	CALCR_MOUSE	Calcitonin receptor	7988453	Cloning and characterization of a mouse brain calcitonin receptor complementary deoxyribonucleic acid and mapping of the calcitonin receptor gene.

O75635	SPB7_HUMAN	Serpin B7	9710452	A mesangium-predominant gene, megsin, is a new serpin upregulated in IgA nephropathy.

Q9Y7N2	MED19_SCHPO	Mediator of RNA polymerase II transcription subunit 19	11572939	Analysis of Schizosaccharomyces pombe mediator reveals a set of essential subunits conserved between yeast and metazoan cells.

Q7KNS3	LIS1_DROME	Lissencephaly-1 homolog	10993674	The Drosophila Lissencephaly1 (DLis1) gene is required for nuclear migration.

Q93890	SRF3_CAEEL	UDP-galactose/UDP-N-acetylglucosamine transporter srf-3	15123614	Loss of srf-3-encoded nucleotide sugar transporter activity in Caenorhabditis elegans alters surface antigenicity and prevents bacterial adherence.

O70343	PRGC1_MOUSE	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha	17618855	Transcriptional control of brown fat determination by PRDM16.

P54647	VATA_DICDI	V-type proton ATPase catalytic subunit A	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q9M2A0	PMA8_ARATH	ATPase 8, plasma membrane-type	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q02224	CENPE_HUMAN	Centromere-associated protein E	9763420	Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1.

Q01196	RUNX1_HUMAN	Runt-related transcription factor 1	8413232	Identification of AML-1 and the (8;21) translocation protein (AML- 1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions.

Q8VE98	CD276_MOUSE	CD276 antigen	12055244	Characterization of mouse and human B7-H3 genes.

Q9PVV4	PCM1_XENLA	Pericentriolar material 1 protein	12571289	Non-membranous granular organelle consisting of PCM-1: subcellular distribution and cell-cycle-dependent assembly/disassembly.

Q14493	SLBP_HUMAN	Histone RNA hairpin-binding protein	18172165	Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'.

P54276	MSH6_MOUSE	DNA mismatch repair protein Msh6	9390556	Mutation in the mismatch repair gene Msh6 causes cancer susceptibility.

P04746	AMYP_HUMAN	Pancreatic alpha-amylase	10769135	Subsite mapping of the human pancreatic alpha-amylase active site through structural, kinetic, and mutagenesis techniques.

Q9H254	SPTN4_HUMAN	Spectrin beta chain, brain 3	11086001	BetaIV spectrin, a new spectrin localized at axon initial segments and nodes of Ranvier in the central and peripheral nervous system.

Q92664	TF3A_HUMAN	Transcription factor IIIA	8063702	Purification and characterization of human transcription factor IIIA.

P50527	STE20_SCHPO	Serine/threonine-protein kinase shk1/pak1	14506270	The novel Rho GTPase-activating protein family protein, Rga8, provides a potential link between Cdc42/p21-activated kinase and Rho signaling pathways in the fission yeast, Schizosaccharomyces pombe.

P22265	TSH_DROME	Protein teashirt	7925029	Homeotic complex and teashirt genes co-operate to establish trunk segmental identities in Drosophila.

Q13956	CNCG_HUMAN	Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	8786098	Isolation and chromosomal localization of the human cone cGMP phosphodiesterase gamma cDNA (PDE6H).

P01600	KV108_HUMAN	Ig kappa chain V-I region Hau	4097974	The primary structure of a monoclonal kappa-type immunoglobulin L- chain of subgroup I (Bence-Jones protein Hau): subdivision within subgroups.

P36873	PP1G_HUMAN	Serine/threonine-protein phosphatase PP1-gamma catalytic subunit	17965019	NOM1 targets protein phosphatase I to the nucleolus.

O46339	HTH_DROME	Homeobox protein homothorax	16778079	Distinct functions of homeodomain-containing and homeodomain-less isoforms encoded by homothorax.

Q9QZK8	DNS2A_RAT	Deoxyribonuclease-2-alpha	10558878	Cloning of a cDNA encoding a rat DNase II-like acid DNase.

P10566	MRS3_YEAST	Mitochondrial RNA-splicing protein MRS3	1703236	MRS3 and MRS4, two suppressors of mtRNA splicing defects in yeast, are new members of the mitochondrial carrier family.

Q61907	PEMT_MOUSE	Phosphatidylethanolamine N-methyltransferase	8978486	Characterization of the murine phosphatidylethanolamine N- methyltransferase-2 gene.

Q76I90	NUF2_CHICK	Kinetochore protein Nuf2	12829748	Dynamic behavior of Nuf2-Hec1 complex that localizes to the centrosome and centromere and is essential for mitotic progression in vertebrate cells.

P09016	HXD4_HUMAN	Homeobox protein Hox-D4	2879245	Differential and stage-related expression in embryonic tissues of a new human homoeobox gene.

P63281	UBC9_RAT	SUMO-conjugating enzyme UBC9	19498170	Rhes, a striatal specific protein, mediates mutant-huntingtin cytotoxicity.

P36402	TCF7_HUMAN	Transcription factor 7	9783587	The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors.

Q54B33	PAKE_DICDI	Serine/threonine-protein kinase pakE	17659086	High-throughput analysis of spatio-temporal dynamics in Dictyostelium.

Q9EXP1	SUFE_DICD3	Cysteine desulfuration protein sufE	12876288	Biogenesis of Fe-S cluster by the bacterial Suf system: SufS and SufE form a new type of cysteine desulfurase.

Q5AHB1	PAN1_CANAL	Actin cytoskeleton-regulatory complex protein PAN1	17431925	Functional analysis of Candida albicans genes whose Saccharomyces cerevisiae homologues are involved in endocytosis.

P47988	TEA1_YEAST	TY1 enhancer activator	8524314	Isolation and analysis of the yeast TEA1 gene, which encodes a zinc cluster Ty enhancer-binding protein.

Q9QY48	DNS2B_MOUSE	Deoxyribonuclease-2-beta	10497274	DLAD, a novel mammalian divalent cation-independent endonuclease with homology to DNase II.

O75874	IDHC_HUMAN	Isocitrate dehydrogenase [NADP] cytoplasmic	9866202	Cytosolic isocitrate dehydrogenase in humans, mice, and voles and phylogenetic analysis of the enzyme family.

Q9UII2	ATIF1_HUMAN	ATPase inhibitor, mitochondrial	10664857	Nucleotide sequence of cDNA coding the mitochondrial precursor protein of the ATPase inhibitor from humans.

Q64700	RBL2_MOUSE	Retinoblastoma-like protein 2	11571651	Association of UNP, a ubiquitin-specific protease, with the pocket proteins pRb, p107 and p130.

O14960	LECT2_HUMAN	Leukocyte cell-derived chemotaxin-2	9545637	Molecular cloning, structural characterization, and chromosomal mapping of the human LECT2 gene.

Q9UJX6	ANC2_HUMAN	Anaphase-promoting complex subunit 2	18485873	Mechanism of ubiquitin-chain formation by the human anaphase- promoting complex.

O02073	TBX18_CAEEL	T-box transcription factor 18	16139225	The T-box transcription factor SEA-1 is an autosomal element of the X:A signal that determines C. elegans sex.

P42227	STAT3_MOUSE	Signal transducer and activator of transcription 3	15004007	Role of the TAK1-NLK-STAT3 pathway in TGF-beta-mediated mesoderm induction.

Q9P7M3	SLX1_SCHPO	Structure-specific endonuclease subunit slx1	14528010	Slx1-Slx4 are subunits of a structure-specific endonuclease that maintains ribosomal DNA in fission yeast.

Q9ZN78	AFRP_STRGR	A-factor receptor protein	2502536	Detection and properties of A-factor-binding protein from Streptomyces griseus.

Q12406	ARP7_YEAST	Actin-related protein 7	9844636	Two actin-related proteins are shared functional components of the chromatin-remodeling complexes RSC and SWI/SNF.

P54274	TERF1_HUMAN	Telomeric repeat-binding factor 1	16166375	Shelterin: the protein complex that shapes and safeguards human telomeres.

Q2M2Z5	KIZ_HUMAN	Centrosomal protein kizuna	19536135	Cep72 regulates the localization of key centrosomal proteins and proper bipolar spindle formation.

Q9NYF8	BCLF1_HUMAN	Bcl-2-associated transcription factor 1	15009215	Emerin binding to Btf, a death-promoting transcriptional repressor, is disrupted by a missense mutation that causes Emery-Dreifuss muscular dystrophy.

Q8VD48	DHRS9_RAT	Dehydrogenase/reductase SDR family member 9	12390888	A novel short-chain alcohol dehydrogenase from rats with retinol dehydrogenase activity, cyclically expressed in uterine epithelium.

P38431	IF5_YEAST	Eukaryotic translation initiation factor 5	9671501	Identification of a translation initiation factor 3 (eIF3) core complex, conserved in yeast and mammals, that interacts with eIF5.

Q9M8K6	MUTE_ARATH	Transcription factor MUTE	17183265	Transcription factor control of asymmetric cell divisions that establish the stomatal lineage.

Q99380	OST4_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST4	10677492	Studies on the role of the hydrophobic domain of Ost4p in interactions with other subunits of yeast oligosaccharyl transferase.

Q9HBE1	PATZ1_HUMAN	POZ-, AT hook-, and zinc finger-containing protein 1	10949935	A novel zinc finger gene is fused to EWS in small round cell tumor.

P48415	SEC16_YEAST	COPII coat assembly protein SEC16	9325247	COPII subunit interactions in the assembly of the vesicle coat.

P57775	FBXW4_HUMAN	F-box/WD repeat-containing protein 4	10405324	A novel human gene encoding an F-box/WD40 containing protein maps in the SHFM3 critical region on 10q24.

P29674	LHX1_XENLA	LIM/homeobox protein Lhx1	8918878	Interactions of the LIM-domain-binding factor Ldb1 with LIM homeodomain proteins.

P23514	COPB_RAT	Coatomer subunit beta	1840503	Beta-COP, a 110 kd protein associated with non-clathrin-coated vesicles and the Golgi complex, shows homology to beta-adaptin.

P32584	STE14_YEAST	Protein-S-isoprenylcysteine O-methyltransferase	2050108	The Saccharomyces cerevisiae STE14 gene encodes a methyltransferase that mediates C-terminal methylation of a-factor and RAS proteins.

Q6FHJ7	SFRP4_HUMAN	Secreted frizzled-related protein 4	10211996	Differential expression of frpHE: a novel human stromal protein of the secreted frizzled gene family, during the endometrial cycle and malignancy.

Q45VV3	YORKI_DROME	Protein yorkie	18256197	In vivo regulation of Yorkie phosphorylation and localization.

Q9SWG3	FAR1_ARATH	Protein FAR-RED IMPAIRED RESPONSE 1	11889039	Arabidopsis FHY3 defines a key phytochrome A signaling component directly interacting with its homologous partner FAR1.

P07143	CY1_YEAST	Cytochrome c1, heme protein, mitochondrial	10873857	Structure at 2.3 A resolution of the cytochrome bc1 complex from the yeast Saccharomyces cerevisiae co-crystallized with an antibody Fv fragment.

O14939	PLD2_HUMAN	Phospholipase D2	9582313	Cloning and initial characterization of a human phospholipase D2 (hPLD2). ADP-ribosylation factor regulates hPLD2.

Q16842	SIA4B_HUMAN	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2	9266697	Cloning and expression of cDNA for a human Gal(beta1-3)GalNAc alpha2,3-sialyltransferase from the CEM T-cell line.

P97534	FKB1B_RAT	Peptidyl-prolyl cis-trans isomerase FKBP1B	9013543	Cyclic ADP-ribose binds to FK506-binding protein 12.6 to release Ca2+ from islet microsomes.

P01764	HV303_HUMAN	Ig heavy chain V-III region VH26	6450418	Structure and multiplicity of genes for the human immunoglobulin heavy chain variable region.

Q09798	PAN2_SCHPO	PAB-dependent poly(A)-specific ribonuclease subunit pan2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q56YA5	SGAT_ARATH	Serine--glyoxylate aminotransferase	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

P40460	NDC80_YEAST	Kinetochore protein NDC80	11266451	The Ndc80p complex from Saccharomyces cerevisiae contains conserved centromere components and has a function in chromosome segregation.

Q8MQJ9	BRAT_DROME	Brain tumor protein	11807032	The Drosophila melanogaster gene brain tumor negatively regulates cell growth and ribosomal RNA synthesis.

Q9P246	STIM2_HUMAN	Stromal interaction molecule 2	16860747	STIM2 is an inhibitor of STIM1-mediated store-operated Ca2+ entry.

Q8VHJ4	TM11D_RAT	Transmembrane protease serine 11D	11439186	Characterization of a serine protease that cleaves pro-gamma- melanotropin at the adrenal to stimulate growth.

P53860	PDR16_YEAST	Phosphatidylinositol transfer protein PDR16	10848624	Identification of a novel family of nonclassic yeast phosphatidylinositol transfer proteins whose function modulates phospholipase D activity and Sec14p-independent cell growth.

O95140	MFN2_HUMAN	Mitofusin-2	11181170	Control of mitochondrial morphology by a human mitofusin.

P29117	PPIF_RAT	Peptidyl-prolyl cis-trans isomerase F, mitochondrial	1599421	Purification and N-terminal sequencing of peptidyl-prolyl cis-trans- isomerase from rat liver mitochondrial matrix reveals the existence of a distinct mitochondrial cyclophilin.

P25638	TAH1_YEAST	TPR repeat-containing protein associated with Hsp90	15766533	Navigating the chaperone network: an integrative map of physical and genetic interactions mediated by the hsp90 chaperone.

P01241	SOMA_HUMAN	Somatotropin	7984244	The X-ray structure of a growth hormone-prolactin receptor complex.

Q13507	TRPC3_HUMAN	Short transient receptor potential channel 3	9215637	Coassembly of TRP and TRPL produces a distinct store-operated conductance.

Q9JLT4	TRXR2_MOUSE	Thioredoxin reductase 2, mitochondrial	10721726	Molecular cloning of mouse thioredoxin reductases.

Q9M390	PTR1_ARATH	Peptide transporter PTR1	15500465	AtPTR1, a plasma membrane peptide transporter expressed during seed germination and in vascular tissue of Arabidopsis.

P49760	CLK2_HUMAN	Dual specificity protein kinase CLK2	7990150	Characterization by cDNA cloning of two new human protein kinases. Evidence by sequence comparison of a new family of mammalian protein kinases.

Q9NR48	ASH1L_HUMAN	Probable histone-lysine N-methyltransferase ASH1L	10860993	huASH1 protein, a putative transcription factor encoded by a human homologue of the Drosophila ash1 gene, localizes to both nuclei and cell-cell tight junctions.

Q7L2H7	EIF3M_HUMAN	Eukaryotic translation initiation factor 3 subunit M	18599441	Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3.

Q19266	KPC3_CAEEL	Protein kinase C-like 3	9422779	Structure, expression, and properties of an atypical protein kinase C (PKC3) from Caenorhabditis elegans. PKC3 is required for the normal progression of embryogenesis and viability of the organism.

P49902	5NTC_HUMAN	Cytosolic purine 5'-nucleotidase	7999131	Molecular cloning of human cytosolic purine 5'-nucleotidase.

Q17990	LITE1_CAEEL	High-energy light unresponsive protein 1	18687026	A novel molecular solution for ultraviolet light detection in Caenorhabditis elegans.

P36979	RLMN_ECOLI	Ribosomal RNA large subunit methyltransferase N	18025251	The methyltransferase YfgB/RlmN is responsible for modification of adenosine 2503 in 23S rRNA.

P84761	ACI_TRIGI	Angiotensin-1-converting enzyme inhibitory peptide	15165718	Isolation and characterization of a novel angiotensin I-converting enzyme inhibitory peptide derived from the edible mushroom Tricholoma giganteum.

Q9WVE8	PACN2_MOUSE	Protein kinase C and casein kinase substrate in neurons protein 2	10431838	PACSIN 2, a novel member of the PACSIN family of cytoplasmic adapter proteins.

P35734	ASK1_YEAST	DASH complex subunit ASK1	15664196	Formation of a dynamic kinetochore-microtubule interface through assembly of the Dam1 ring complex.

P42559	ALLS_MANSE	Allatostatin	1946359	Identification of an allatostatin from the tobacco hornworm Manduca sexta.

Q02088	TPM_SCHPO	Tropomyosin	1436080	A new tropomyosin essential for cytokinesis in the fission yeast S. pombe.

Q62796	RBP1_RAT	RalA-binding protein 1	9973605	Cytocentrin is a Ral-binding protein involved in the assembly and function of the mitotic apparatus.

P82384	LCP9_DROME	Larval cuticle protein 9	9654737	Identification of proteins and developmental expression of RNAs encoded by the 65A cuticle protein gene cluster in Drosophila melanogaster.

Q9UNL4	ING4_HUMAN	Inhibitor of growth protein 4	15029197	The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis.

Q8IWX5	SGPP2_HUMAN	Sphingosine-1-phosphate phosphatase 2	12411432	Identification and characterization of a novel human sphingosine-1- phosphate phosphohydrolase, hSPP2.

P40491	FMC1_YEAST	ATP synthase assembly factor FMC1, mitochondrial	11096112	Identification of a nuclear gene (FMC1) required for the assembly/stability of yeast mitochondrial F(1)-ATPase in heat stress conditions.

Q08702	APTX_YEAST	Aprataxin-like protein	16964241	The neurodegenerative disease protein aprataxin resolves abortive DNA ligation intermediates.

Q9JHS4	CLPX_MOUSE	ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial	10347188	Molecular cloning and characterization of a mouse homolog of bacterial ClpX, a novel mammalian class II member of the Hsp100/Clp chaperone family.

P05747	RL29_YEAST	60S ribosomal protein L29	14562095	Global analysis of protein localization in budding yeast.

Q13671	RIN1_HUMAN	Ras and Rab interactor 1	9144171	Protein binding and signaling properties of RIN1 suggest a unique effector function.

Q61048	WBP4_MOUSE	WW domain-binding protein 4	9724750	WW domain-mediated interactions reveal a spliceosome-associated protein that binds a third class of proline-rich motif: the proline glycine and methionine-rich motif.

P20807	CAN3_HUMAN	Calpain-3	2555341	Molecular cloning of a novel mammalian calcium-dependent protease distinct from both m- and mu-types. Specific expression of the mRNA in skeletal muscle.

Q8IPH9	SLOB_DROME	Slowpoke-binding protein	9539129	Slob, a novel protein that interacts with the Slowpoke calcium- dependent potassium channel.

Q6I9Y2	THOC7_HUMAN	THO complex subunit 7 homolog	18974867	Recruitment of the complete hTREX complex is required for Kaposi's sarcoma-associated herpesvirus intronless mRNA nuclear export and virus replication.

Q29PV4	IDL1_ARATH	Protein IDA-LIKE 1	18660431	The EPIP peptide of INFLORESCENCE DEFICIENT IN ABSCISSION is sufficient to induce abscission in arabidopsis through the receptor- like kinases HAESA and HAESA-LIKE2.

O59780	YCN3_SCHPO	Uncharacterized transcriptional regulatory protein C320.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Y5S9	RBM8A_HUMAN	RNA-binding protein 8A	11013075	Identification and structural analysis of human RBM8A and RBM8B: two highly conserved RNA-binding motif proteins that interact with OVCA1, a candidate tumor suppressor.

Q04636	POB3_YEAST	FACT complex subunit POB3	11432837	Spt16-Pob3 and the HMG protein Nhp6 combine to form the nucleosome- binding factor SPN.

Q99246	CAC1D_MOUSE	Voltage-dependent L-type calcium channel subunit alpha-1D	12900400	Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.

P25638	TAH1_YEAST	TPR repeat-containing protein associated with Hsp90	14562095	Global analysis of protein localization in budding yeast.

Q8R4U1	MYPOP_MOUSE	Myb-related transcription factor, partner of profilin	15615774	Profilin regulates the activity of p42POP, a novel Myb-related transcription factor.

P33607	NUOL_ECOLI	NADH-quinone oxidoreductase subunit L	15919996	Global topology analysis of the Escherichia coli inner membrane proteome.

Q9UJY5	GGA1_HUMAN	ADP-ribosylation factor-binding protein GGA1	12679809	Molecular mechanism of membrane recruitment of GGA by ARF in lysosomal protein transport.

P02651	APOA4_RAT	Apolipoprotein A-IV	6591177	Rat apolipoprotein A-IV contains 13 tandem repetitions of a 22-amino acid segment with amphipathic helical potential.

P11216	PYGB_HUMAN	Glycogen phosphorylase, brain form	3346228	Human brain glycogen phosphorylase. Cloning, sequence analysis, chromosomal mapping, tissue expression, and comparison with the human liver and muscle isozymes.

Q93ZY2	ROGF1_ARATH	Rop guanine nucleotide exchange factor 1	16415208	Members of a novel class of Arabidopsis Rho guanine nucleotide exchange factors control Rho GTPase-dependent polar growth.

Q5SXM2	SNPC4_HUMAN	snRNA-activating protein complex subunit 4	9418884	The large subunit of basal transcription factor SNAPc is a Myb domain protein that interacts with Oct-1.

Q7Z203	CUPB_DICDI	Calcium up-regulated protein B	14871937	The Ca2+/calcineurin-regulated cup gene family in Dictyostelium discoideum and its possible involvement in development.

Q13489	BIRC3_HUMAN	Baculoviral IAP repeat-containing protein 3	8552191	Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes.

O65312	MEDEA_ARATH	Histone-lysine N-methyltransferase MEDEA	10962025	Expression and parent-of-origin effects for FIS2, MEA, and FIE in the endosperm and embryo of developing Arabidopsis seeds.

Q08726	GPN2_YEAST	GPN-loop GTPase 2 homolog	14690591	Assigning function to yeast proteins by integration of technologies.

Q925K9	TSSK6_MOUSE	Testis-specific serine/threonine-protein kinase 6	15870294	Identification and characterization of SSTK, a serine/threonine protein kinase essential for male fertility.

P61158	ARP3_HUMAN	Actin-related protein 3	9230079	The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly.

Q86YB8	ERO1B_HUMAN	ERO1-like protein beta	10818100	Endoplasmic reticulum oxidoreductin 1-lbeta (ERO1-Lbeta), a human gene induced in the course of the unfolded protein response.

O36030	YEKI_SCHPO	Uncharacterized WD repeat-containing protein C4F10.18	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P41812	POP1_YEAST	Ribonucleases P/MRP protein subunit POP1	9620854	Purification and characterization of the nuclear RNase P holoenzyme complex reveals extensive subunit overlap with RNase MRP.

O09159	MA2B1_MOUSE	Lysosomal alpha-mannosidase	9305783	Cloning, expression, purification, and characterization of the murine lysosomal acid alpha-mannosidase.

P40124	CAP1_MOUSE	Adenylyl cyclase-associated protein 1	7691848	Identification and characterization of a cDNA encoding mouse CAP: a homolog of the yeast adenylyl cyclase associated protein.

Q9BPX6	MICU1_HUMAN	Calcium uptake protein 1, mitochondrial	9806765	Isolation of cDNA clones coding for IgE autoantigens with serum IgE from atopic dermatitis patients.

O94640	SIR2_SCHPO	NAD-dependent histone deacetylase sir2	15545655	Conserved locus-specific silencing functions of Schizosaccharomyces pombe sir2+.

O94494	SIM4_SCHPO	Centromere protein sim4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P13942	COBA2_HUMAN	Collagen alpha-2(XI) chain	7859284	Autosomal dominant and recessive osteochondrodysplasias associated with the COL11A2 locus.

Q9H0E9	BRD8_HUMAN	Bromodomain-containing protein 8	14966270	Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans.

Q04651	ERV41_YEAST	ER-derived vesicles protein ERV41	11157978	Erv41p and Erv46p: new components of COPII vesicles involved in transport between the ER and Golgi complex.

P38266	AIM3_YEAST	Altered inheritance of mitochondria protein 3	15561700	Characterizing the sphingolipid signaling pathway that remediates defects associated with loss of the yeast amphiphysin-like orthologs, Rvs161p and Rvs167p.

P20267	PO3F1_RAT	POU domain, class 3, transcription factor 1	1975954	Expression and activity of the POU transcription factor SCIP.

O13833	CID1_SCHPO	Poly(A) RNA polymerase protein cid1	10757807	Cid1, a fission yeast protein required for S-M checkpoint control when DNA polymerase delta or epsilon is inactivated.

P13350	CCNB1_XENLA	G2/mitotic-specific cyclin-B1	7622566	Members of the NAP/SET family of proteins interact specifically with B-type cyclins.

P53152	MMS2_YEAST	Ubiquitin-conjugating enzyme variant MMS2	9576943	MMS2, encoding a ubiquitin-conjugating-enzyme-like protein, is a member of the yeast error-free postreplication repair pathway.

O74448	PIN1_SCHPO	Peptidyl-prolyl cis-trans isomerase pin1	11707530	Isolation and characterization of the Pin1/Ess1p homologue in Schizosaccharomyces pombe.

P82140	DLP2_ORNAN	Defensin-like peptide 2/4	10417345	Solution structure of a defensin-like peptide from platypus venom.

Q12500	AVL9_YEAST	Late secretory pathway protein AVL9	14562095	Global analysis of protein localization in budding yeast.

P04156	PRIO_HUMAN	Major prion protein	3755672	Molecular cloning of a human prion protein cDNA.

Q9FT52	ATP5H_ARATH	ATP synthase subunit d, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P54000	SUB1_YEAST	RNA polymerase II transcriptional coactivator SUB1	8617240	Yeast SUB1 is a suppressor of TFIIB mutations and has homology to the human co-activator PC4.

Q16526	CRY1_HUMAN	Cryptochrome-1	8909283	Putative human blue-light photoreceptors hCRY1 and hCRY2 are flavoproteins.

Q06675	MCM21_YEAST	Central kinetochore subunit MCM21	10323865	A putative protein complex consisting of Ctf19, Mcm21, and Okp1 represents a missing link in the budding yeast kinetochore.

Q9JHG0	CBLN3_MOUSE	Cerebellin-3	10964938	Cbln3, a novel member of the precerebellin family that binds specifically to Cbln1.

Q9P789	YN8E_SCHPO	Pumilio domain-containing protein P35G2.14	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P70583	DUT_RAT	Deoxyuridine 5'-triphosphate nucleotidohydrolase	8910358	Cloning and identification of rat deoxyuridine triphosphatase as an inhibitor of peroxisome proliferator-activated receptor alpha.

Q9H488	OFUT1_HUMAN	GDP-fucose protein O-fucosyltransferase 1	11524432	Modification of epidermal growth factor-like repeats with O-fucose: molecular cloning and expression of a novel GDP-fucose protein O- fucosyltransferase.

P21781	FGF7_HUMAN	Keratinocyte growth factor	2915979	Purification and characterization of a newly identified growth factor specific for epithelial cells.

P39729	RBG1_YEAST	GTP-binding protein RBG1	14562095	Global analysis of protein localization in budding yeast.

P38182	ATG8_YEAST	Autophagy-related protein 8	9649430	Aut2p and Aut7p, two novel microtubule-associated proteins are essential for delivery of autophagic vesicles to the vacuole.

O94414	LNP_SCHPO	Protein lunapark homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

A1XGB4	PIMP1_CAPAN	UPF0497 membrane protein PIMP1	18936963	The promoter of the pepper pathogen-induced membrane protein gene CaPIMP1 mediates environmental stress responses in plants.

P39371	NANM_ECOLI	N-acetylneuraminate epimerase	18063573	Sialic acid mutarotation is catalyzed by the Escherichia coli beta- propeller protein YjhT.

O94487	PPK35_SCHPO	Serine/threonine-protein kinase ppk35	15821139	Systematic deletion analysis of fission yeast protein kinases.

P11978	SIR4_YEAST	Regulatory protein SIR4	14551211	Separation-of-function mutants of yeast Ku80 reveal a Yku80p-Sir4p interaction involved in telomeric silencing.

Q60749	KHDR1_MOUSE	KH domain-containing, RNA-binding, signal transduction-associated protein 1	9315629	Self-association of the single-KH-domain family members Sam68, GRP33, GLD-1, and Qk1: role of the KH domain.

Q92349	MUG79_SCHPO	Meiotically up-regulated gene 79 protein	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

Q9Y4K3	TRAF6_HUMAN	TNF receptor-associated factor 6	19675569	Direct activation of protein kinases by unanchored polyubiquitin chains.

P25992	YEMA_DROME	Yemanuclein-alpha	1606021	The yemanuclein-alpha: a new Drosophila DNA binding protein specific for the oocyte nucleus.

Q96C11	FGGY_HUMAN	FGGY carbohydrate kinase domain-containing protein	17671248	Whole-genome analysis of sporadic amyotrophic lateral sclerosis.

P18169	DEC11_DROME	Defective chorion-1 protein, FC125 isoform	3378704	Cloning and analysis of the dec-1 female-sterile locus, a gene required for proper assembly of the Drosophila eggshell.

P12389	ACHA2_RAT	Neuronal acetylcholine receptor subunit alpha-2	2832952	Functional expression of a new pharmacological subtype of brain nicotinic acetylcholine receptor.

Q9XTY6	NUMB1_CAEEL	Numb-related protein 1	11134024	A novel adapter protein employs a phosphotyrosine binding domain and exceptionally basic N-terminal domains to capture and localize an atypical protein kinase C: characterization of Caenorhabditis elegans C kinase adapter 1, a protein that avidly binds protein kinase C3.

Q92952	KCNN1_HUMAN	Small conductance calcium-activated potassium channel protein 1	8781233	Small-conductance, calcium-activated potassium channels from mammalian brain.

Q8WXF3	REL3_HUMAN	Relaxin-3	12506116	H3 relaxin is a specific ligand for LGR7 and activates the receptor by interacting with both the ectodomain and the exoloop 2.

Q62440	TLE1_MOUSE	Transducin-like enhancer protein 1	12359720	Characterization of a novel mammalian groucho isoform and its role in transcriptional regulation.

P55075	FGF8_HUMAN	Fibroblast growth factor 8	8891346	Molecular cloning and characterization of human FGF8 alternative messenger RNA forms.

Q9BYM8	UB7I3_HUMAN	RanBP-type and C3HC4-type zinc finger-containing protein 1	20005846	Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction.

Q6IMN6	CAPR2_HUMAN	Caprin-2	14593112	Cloning and characterization of a gene expressed during terminal differentiation that encodes a novel inhibitor of growth.

Q12398	HMS1_YEAST	Probable transcription factor HMS1	9832522	Regulators of pseudohyphal differentiation in Saccharomyces cerevisiae identified through multicopy suppressor analysis in ammonium permease mutant strains.

Q62384	ZPR1_MOUSE	Zinc finger protein ZPR1	8650580	Binding of zinc finger protein ZPR1 to the epidermal growth factor receptor.

O76064	RNF8_HUMAN	E3 ubiquitin-protein ligase RNF8	18001825	RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly.

Q15648	MED1_HUMAN	Mediator of RNA polymerase II transcription subunit 1	12037571	Transcription coactivator TRAP220 is required for PPAR gamma 2- stimulated adipogenesis.

P42945	UTP10_YEAST	U3 small nucleolar RNA-associated protein 10	12068309	A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis.

Q96FE5	LIGO1_HUMAN	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1	14966521	LINGO-1 is a component of the Nogo-66 receptor/p75 signaling complex.

Q66PJ3	AR6P4_HUMAN	ADP-ribosylation factor-like protein 6-interacting protein 4	10708573	Molecular cloning and expression analysis of a putative nuclear protein, SR-25.

O15229	KMO_HUMAN	Kynurenine 3-monooxygenase	10672018	Functional characterization and mechanism of action of recombinant human kynurenine 3-hydroxylase.

P13533	MYH6_HUMAN	Myosin-6	1776652	Complete sequence of human cardiac alpha-myosin heavy chain gene and amino acid comparison to other myosins based on structural and functional differences.

P59769	GRP78_ASPAW	78 kDa glucose-regulated protein homolog	9294262	Characterization of the bip gene of Aspergillus awamori encoding a protein with an HDEL retention signal homologous to the mammalian BiP involved in polypeptide secretion.

Q9SYX2	SPA1_ARATH	Protein SUPPRESSOR OF PHYA-105 1	11461903	The phytochrome A-specific signaling intermediate SPA1 interacts directly with COP1, a constitutive repressor of light signaling in Arabidopsis.

P51511	MMP15_HUMAN	Matrix metalloproteinase-15	7649159	cDNA sequence and mRNA tissue distribution of a novel human matrix metalloproteinase with a potential transmembrane segment.

Q9VD74	GR93C_DROME	Putative gustatory receptor 93c	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

Q9QZI7	TSAP1_RAT	tRNA selenocysteine 1-associated protein 1	10606267	Identification of a protein component of a mammalian tRNA(Sec) complex implicated in the decoding of UGA as selenocysteine.

Q9H310	RHBG_HUMAN	Ammonium transporter Rh type B	15929723	Human Rhesus B and Rhesus C glycoproteins: properties of facilitated ammonium transport in recombinant kidney cells.

Q13255	GRM1_HUMAN	Metabotropic glutamate receptor 1	9076744	Human metabotropic glutamate receptor 1: mRNA distribution, chromosome localization and functional expression of two splice variants.

Q8TD17	ZN398_HUMAN	Zinc finger protein 398	11779858	A novel zinc finger transcription factor with two isoforms that are differentially repressed by estrogen receptor-alpha.

Q9UBY5	LPAR3_HUMAN	Lysophosphatidic acid receptor 3	10488122	Molecular cloning and characterization of a novel human G-protein- coupled receptor, EDG7, for lysophosphatidic acid.

P33477	ANX11_RABIT	Annexin A11	9497364	Regulation of calcyclin (S100A6) binding by alternative splicing in the N-terminal regulatory domain of annexin XI isoforms.

Q8WWI1	LMO7_HUMAN	LIM domain only protein 7	9826547	Analysis of a human cDNA containing a tissue-specific alternatively spliced LIM domain.

Q04119	PPN1_YEAST	Endopolyphosphatase	11566881	Sorting of proteins into multivesicular bodies: ubiquitin-dependent and -independent targeting.

P47739	AL3A1_MOUSE	Aldehyde dehydrogenase, dimeric NADP-preferring	8148869	Mouse dioxin-inducible cytosolic aldehyde dehydrogenase-3: AHD4 cDNA sequence, genetic mapping, and differences in mRNA levels.

P35436	NMDE1_MOUSE	Glutamate [NMDA] receptor subunit epsilon-1	19243221	Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning.

Q9CQI6	COTL1_MOUSE	Coactosin-like protein	11785969	Molecular cloning and functional characterization of mouse coactosin- like protein.

Q12788	TBL3_HUMAN	Transducin beta-like protein 3	8307582	A transducin-like gene maps to the autosomal dominant polycystic kidney disease gene region.

Q9LX07	ANXD7_ARATH	Annexin D7	16531057	Expression profiling of the Arabidopsis annexin gene family during germination, de-etiolation and abiotic stress.

O13807	DDB1_SCHPO	DNA damage-binding protein 1	15805471	Ddb1 controls genome stability and meiosis in fission yeast.

Q96NY8	PVRL4_HUMAN	Poliovirus receptor-related protein 4	11544254	Nectin4/PRR4, a new afadin-associated member of the nectin family that trans-interacts with nectin1/PRR1 through V domain interaction.

Q94AX4	DLD_ARATH	D-lactate dehydrogenase [cytochrome], mitochondrial	19586914	Two D-2-hydroxy-acid dehydrogenases in Arabidopsis thaliana with catalytic capacities to participate in the last reactions of the methylglyoxal and beta-oxidation pathways.

Q64335	KLRG1_RAT	Killer cell lectin-like receptor subfamily G member 1	9120279	Analysis of the genes encoding the mast cell function-associated antigen and its alternatively spliced transcripts.

Q9FNX8	LOX4_ARATH	Lipoxygenase 4, chloroplastic	12609040	Expression profiling of the host response to bacterial infection: the transition from basal to induced defence responses in RPM1-mediated resistance.

P49598	P2C37_ARATH	Protein phosphatase 2C 37	12034902	Physical and functional interaction of the Arabidopsis K(+) channel AKT2 and phosphatase AtPP2CA.

P01112	RASH_HUMAN	GTPase HRas	9219684	The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants.

Q9FJX6	FH6_ARATH	Formin-like protein 6	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P20604	PP11_YEAST	Serine/threonine-protein phosphatase PP1-1	1848673	The SIT4 protein phosphatase functions in late G1 for progression into S phase.

P0ADG4	SUHB_ECOLI	Inositol-1-monophosphatase	10747806	Overexpression, purification, and analysis of complementation behavior of E. coli SuhB protein: comparison with bacterial and archaeal inositol monophosphatases.

Q9LTR2	TGD2_ARATH	Protein TRIGALACTOSYLDIACYLGLYCEROL 2, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q9JHE3	ASAH2_MOUSE	Neutral ceramidase	10753931	Molecular cloning of the full-length cDNA encoding mouse neutral ceramidase. A novel but highly conserved gene family of neutral/alkaline ceramidases.

Q9RR97	NOSO_DEIRA	Nitric oxide synthase oxygenase	11756668	Cloning, expression, and characterization of a nitric oxide synthase protein from Deinococcus radiodurans.

P40967	PME17_HUMAN	Melanocyte protein Pmel 17	8179825	Cloning and expression of the gene for the melanoma-associated ME20 antigen.

P50077	CCH1_YEAST	Calcium-channel protein CCH1	9343395	A homolog of mammalian, voltage-gated calcium channels mediates yeast pheromone-stimulated Ca2+ uptake and exacerbates the cdc1(Ts) growth defect.

Q08921	TCO89_YEAST	Target of rapamycin complex 1 subunit TCO89	14736892	TOR complex 1 includes a novel component, Tco89p (YPL180w), and cooperates with Ssd1p to maintain cellular integrity in Saccharomyces cerevisiae.

P33299	PRS7_YEAST	26S protease regulatory subunit 7 homolog	10688918	Physical association of ubiquitin ligases and the 26S proteasome.

P08865	RSSA_HUMAN	40S ribosomal protein SA	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

P33026	SETB_ECOLI	Sugar efflux transporter B	10438463	Functional and biochemical characterization of Escherichia coli sugar efflux transporters.

P48727	GLC7B_CAEEL	Serine/threonine-protein phosphatase PP1-beta	12837290	Role of Caenorhabditis elegans protein phosphatase type 1, CeGLC-7 beta, in metaphase to anaphase transition during embryonic development.

O13988	POT1_SCHPO	Protection of telomeres protein 1	11349150	Pot1, the putative telomere end-binding protein in fission yeast and humans.

P28004	PRP45_YEAST	Pre-mRNA-processing protein 45	12359070	Functional mapping of Saccharomyces cerevisiae Prp45 identifies the SNW domain as essential for viability.

O15218	GP182_HUMAN	G-protein coupled receptor 182	9367907	Molecular cloning of a novel human receptor gene with homology to the rat adrenomedullin receptor and high expression in heart and immune system.

Q12155	YL050_YEAST	Uncharacterized membrane protein YLR050C	14562095	Global analysis of protein localization in budding yeast.

Q96HU1	SGSM3_HUMAN	Small G protein signaling modulator 3	17509819	Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway.

P36108	DID4_YEAST	DOA4-independent degradation protein 4	12194857	Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting.

P0A6C5	ARGA_ECOLI	Amino-acid acetyltransferase	16890	N-acetylglutamate synthase of Escherichia coli: purification, characterization, and molecular properties.

Q17389	CUL1_CAEEL	Cullin-1	17392428	Regulation of Caenorhabditis elegans lifespan by a proteasomal E3 ligase complex.

Q91V87	FGRL1_MOUSE	Fibroblast growth factor receptor-like 1	12813049	Characterization of FGFRL1, a novel fibroblast growth factor (FGF) receptor preferentially expressed in skeletal tissues.

P39515	TIM17_YEAST	Mitochondrial import inner membrane translocase subunit TIM17	15618217	Conserved N-terminal negative charges in the Tim17 subunit of the TIM23 translocase play a critical role in the import of preproteins into mitochondria.

Q9XWI6	EIF3B_CAEEL	Eukaryotic translation initiation factor 3 subunit B	17411345	Lifespan regulation by evolutionarily conserved genes essential for viability.

Q39023	MPK3_ARATH	Mitogen-activated protein kinase 3	8570631	A gene encoding a mitogen-activated protein kinase kinase kinase is induced simultaneously with genes for a mitogen-activated protein kinase and an S6 ribosomal protein kinase by touch, cold, and water stress in Arabidopsis thaliana.

P05933	CALM_SCHPO	Calmodulin	3035538	Analysis and in vivo disruption of the gene coding for calmodulin in Schizosaccharomyces pombe.

Q9R1X4	TIM_MOUSE	Protein timeless homolog	10963667	A role for Timeless in epithelial morphogenesis during kidney development.

Q92963	RIT1_HUMAN	GTP-binding protein Rit1	10545207	Biochemical characterization of the Ras-related GTPases Rit and Rin.

O18373	SPS1_DROME	Selenide, water dikinase	9491069	patufet, the gene encoding the Drosophila melanogaster homologue of selenophosphate synthetase, is involved in imaginal disc morphogenesis.

Q38937	RAC5_ARATH	Rac-like GTP-binding protein ARAC5	9349271	Cloning and characterization of rac-like cDNAs from Arabidopsis thaliana.

P55054	FABP9_RAT	Fatty acid-binding protein 9	7958448	A novel testicular protein, with sequence similarities to a family of lipid binding proteins, is a major component of the rat sperm perinuclear theca.

P41921	GSHR_YEAST	Glutathione reductase	7737505	Isolation, characterization and overexpression of the yeast gene, GLR1, encoding glutathione reductase.

Q9UKK6	NXT1_HUMAN	NTF2-related export protein 1	10567585	Identification of an NTF2-related factor that binds Ran-GTP and regulates nuclear protein export.

O35775	SYCN_RAT	Syncollin	9244306	The secretory granule protein syncollin binds to syntaxin in a Ca2(+)-sensitive manner.

Q12692	H2AZ_YEAST	Histone H2A.Z	11081628	Histone H2A.Z regulates transcription and is partially redundant with nucleosome remodeling complexes.

Q9US09	BTN1_SCHPO	Protein btn1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9P0L2	MARK1_HUMAN	Serine/threonine-protein kinase MARK1	9108484	MARK - a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption.

P32479	HIR1_YEAST	Protein HIR1	9001207	Hir1p and Hir2p function as transcriptional corepressors to regulate histone gene transcription in the Saccharomyces cerevisiae cell cycle.

Q80Z25	OFD1_MOUSE	Oral-facial-digital syndrome 1 protein homolog	16311594	Oral-facial-digital type I protein is required for primary cilia formation and left-right axis specification.

Q8NBQ5	DHB11_HUMAN	Estradiol 17-beta-dehydrogenase 11	12697717	17 beta-hydroxysteroid dehydrogenase type XI localizes to human steroidogenic cells.

Q9NRP7	STK36_HUMAN	Serine/threonine-protein kinase 36	10806483	Gli regulation by the opposing activities of fused and suppressor of fused.

Q8C050	KS6A5_MOUSE	Ribosomal protein S6 kinase alpha-5	12628924	Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1).

Q9C5J7	K6PF7_ARATH	6-phosphofructokinase 7	17485088	Characterisation of the ATP-dependent phosphofructokinase gene family from Arabidopsis thaliana.

Q8GWC3	PR1A2_ARATH	PRA1 family protein A2	18583532	The PRA1 gene family in Arabidopsis.

Q12340	YRM1_YEAST	Zinc finger transcription factor YRM1	14512416	Competitive promoter occupancy by two yeast paralogous transcription factors controlling the multidrug resistance phenomenon.

P27661	H2AX_MOUSE	Histone H2A.x	11934988	Genomic instability in mice lacking histone H2AX.

O00182	LEG9_HUMAN	Galectin-9	9045665	Molecular definition of a novel human galectin which is immunogenic in patients with Hodgkin's disease.

P51150	RAB7A_MOUSE	Ras-related protein Rab-7a	12972561	Rabring7, a novel Rab7 target protein with a RING finger motif.

P02585	TNNC2_HUMAN	Troponin C, skeletal muscle	2373703	Cloning, structural analysis, and expression of the human fast twitch skeletal muscle troponin C gene.

P84742	PBL1F_EUGGR	Photoactivated adenylate cyclase subunit beta-like protein 1224-5/1F	16121285	Photoactivated adenylyl cyclase (PAC) genes in the flagellate Euglena gracilis mutant strains.

Q9Y3B7	RM11_HUMAN	39S ribosomal protein L11, mitochondrial	11543634	The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders.

Q07913	NSE1_YEAST	Non-structural maintenance of chromosomes element 1	11927594	Identification of a novel non-structural maintenance of chromosomes (SMC) component of the SMC5-SMC6 complex involved in DNA repair.

P70056	FOXH1_XENLA	Forkhead box protein H1	10473623	The role of FAST-1 and Smads in transcriptional regulation by activin during early Xenopus embryogenesis.

P39055	DYN1_CAEEL	Dynamin	9294229	A dynamin GTPase mutation causes a rapid and reversible temperature- inducible locomotion defect in C. elegans.

P41816	OYE3_YEAST	NADPH dehydrogenase 3	7836424	A new old yellow enzyme of Saccharomyces cerevisiae.

Q9Y2T5	GPR52_HUMAN	Probable G-protein coupled receptor 52	9931487	Identification and cloning of three novel human G protein-coupled receptor genes GPR52, PsiGPR53 and GPR55: GPR55 is extensively expressed in human brain.

Q6NML0	ATL76_ARATH	E3 ubiquitin-protein ligase ATL76	15644464	Functional analysis of the RING-type ubiquitin ligase family of Arabidopsis.

O95841	ANGL1_HUMAN	Angiopoietin-related protein 1	10025962	Molecular cloning and characterization of a novel angiopoietin family protein, angiopoietin-3.

P38248	ECM33_YEAST	Cell wall protein ECM33	9335584	Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae.

Q9WU61	CLCC1_RAT	Chloride channel CLIC-like protein 1	11279057	Identification of a novel chloride channel expressed in the endoplasmic reticulum, Golgi apparatus, and nucleus.

Q9FZ48	UBC36_ARATH	Ubiquitin-conjugating enzyme E2 36	20113438	A lysine-63-linked ubiquitin chain-forming conjugase, UBC13, promotes the developmental responses to iron deficiency in Arabidopsis roots.

P46989	ATG27_YEAST	Autophagy-related protein 27	17135291	Atg27 is required for autophagy-dependent cycling of Atg9.

P32245	MC4R_HUMAN	Melanocortin receptor 4	19737927	Mahogunin ring finger-1 (MGRN1) E3 ubiquitin ligase inhibits signaling from melanocortin receptor by competition with Galphas.

P23116	EIF3A_MOUSE	Eukaryotic translation initiation factor 3 subunit A	17581632	Reconstitution reveals the functional core of mammalian eIF3.

Q00535	CDK5_HUMAN	Cell division protein kinase 5	14521924	Apoptosis-associated tyrosine kinase is a Cdk5 activator p35 binding protein.

C8YR32	LOXH1_MOUSE	Lipoxygenase homology domain-containing protein 1	19732867	Mutations in LOXHD1, an evolutionarily conserved stereociliary protein, disrupt hair cell function in mice and cause progressive hearing loss in humans.

P21514	YAHA_ECOLI	Cyclic di-GMP phosphodiesterase yahA	15995192	The ubiquitous protein domain EAL is a cyclic diguanylate-specific phosphodiesterase: enzymatically active and inactive EAL domains.

Q9UQ03	COR2B_HUMAN	Coronin-2B	10224093	A neurally enriched coronin-like protein, ClipinC, is a novel candidate for an actin cytoskeleton-cortical membrane-linking protein.

Q9P795	AIR1_SCHPO	Protein air1	17512405	RNAi-dependent and -independent RNA turnover mechanisms contribute to heterochromatic gene silencing.

Q9W5D4	POMT2_DROME	Protein O-mannosyl-transferase 2	15271988	The twisted abdomen phenotype of Drosophila POMT1 and POMT2 mutants coincides with their heterophilic protein O-mannosyltransferase activity.

O13800	RDL1_SCHPO	DNA repair protein rdl1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9LPV9	LWD1_ARATH	WD repeat-containing protein LWD1	18676661	Two new clock proteins, LWD1 and LWD2, regulate Arabidopsis photoperiodic flowering.

P60896	DSS1_HUMAN	26S proteasome complex subunit DSS1	10373512	Interaction between the product of the breast cancer susceptibility gene BRCA2 and DSS1, a protein functionally conserved from yeast to mammals.

Q07804	YEH1_YEAST	Sterol esterase 1	15713625	The Saccharomyces cerevisiae YLL012/YEH1, YLR020/YEH2, and TGL1 genes encode a novel family of membrane-anchored lipases that are required for steryl ester hydrolysis.

Q0ZGT2	NEXN_HUMAN	Nexilin	15823560	NELIN, a new F-actin associated protein, stimulates HeLa cell migration and adhesion.

O75376	NCOR1_HUMAN	Nuclear receptor corepressor 1	11931768	The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2.

Q03565	BAF1_CAEEL	Barrier-to-autointegration factor 1	12684533	MAN1 and emerin have overlapping function(s) essential for chromosome segregation and cell division in Caenorhabditis elegans.

P53921	YNM2_YEAST	Putative mitochondrial ribosomal protein YNL122C	14562095	Global analysis of protein localization in budding yeast.

Q8R4A3	DACT1_MOUSE	Dapper homolog 1	11970895	Dapper, a Dishevelled-associated antagonist of beta-catenin and JNK signaling, is required for notochord formation.

P91645	CAC1A_DROME	Voltage-dependent calcium channel type A subunit alpha-1	9649530	Courtship and visual defects of cacophony mutants reveal functional complexity of a calcium-channel alpha1 subunit in Drosophila.

Q02932	KA120_YEAST	Importin beta-like protein KAP120	10684247	The yeast nuclear pore complex: composition, architecture, and transport mechanism.

P38768	PIH1_YEAST	Protein interacting with Hsp90 1	15766533	Navigating the chaperone network: an integrative map of physical and genetic interactions mediated by the hsp90 chaperone.

Q16828	DUS6_HUMAN	Dual specificity protein phosphatase 6	8670865	Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase.

Q9XVN3	IASPP_CAEEL	Apoptotic enhancer 1 protein	12524540	iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human.

Q09131	PPAF_SOYBN	Purple acid phosphatase	10510276	Binuclear metal centers in plant purple acid phosphatases: Fe-Mn in sweet potato and Fe-Zn in soybean.

Q9MZ03	CD38_RABIT	ADP-ribosyl cyclase 1	10477767	CD38/ADP-ribosyl cyclase: a new role in the regulation of osteoclastic bone resorption.

P53889	FMP41_YEAST	Uncharacterized mitochondrial hydrolase FMP41	14562095	Global analysis of protein localization in budding yeast.

Q8WXF7	ATLA1_HUMAN	Atlastin-1	19665976	A class of dynamin-like GTPases involved in the generation of the tubular ER network.

O61661	CHK1_DROME	Serine/threonine-protein kinase grp	9197245	The Drosophila grapes gene is related to checkpoint gene chk1/rad27 and is required for late syncytial division fidelity.

P50488	DAF4_CAEEL	Cell surface receptor daf-4	8413626	The daf-4 gene encodes a bone morphogenetic protein receptor controlling C. elegans dauer larva development.

O13894	MU103_SCHPO	Meiotically up-regulated gene 103 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P49711	CTCF_HUMAN	Transcriptional repressor CTCF	17827499	Critical DNA binding interactions of the insulator protein CTCF: a small number of zinc fingers mediate strong binding, and a single finger-DNA interaction controls binding at imprinted loci.

Q9UIL4	KIF25_HUMAN	Kinesin-like protein KIF25	9925916	Identification, genomic organization, and alternative splicing of KNSL3, a novel human gene encoding a kinesin-like protein.

O15083	ERC2_HUMAN	ERC protein 2	12923177	Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins.

Q9BZD4	NUF2_HUMAN	Kinetochore protein Nuf2	11266451	The Ndc80p complex from Saccharomyces cerevisiae contains conserved centromere components and has a function in chromosome segregation.

Q9H490	PIGU_HUMAN	Phosphatidylinositol glycan anchor biosynthesis class U protein	12802054	Human PIG-U and yeast Cdc91p are the fifth subunit of GPI transamidase that attaches GPI-anchors to proteins.

Q9Y5H6	PCDA8_HUMAN	Protocadherin alpha-8	10380929	A striking organization of a large family of human neural cadherin- like cell adhesion genes.

Q9JJZ6	KLF13_MOUSE	Krueppel-like factor 13	10642511	Mouse BTEB3, a new member of the basic transcription element binding protein (BTEB) family, activates expression from GC-rich minimal promoter regions.

Q02971	CADH7_ARATH	Cinnamyl alcohol dehydrogenase 7	14745009	Functional reclassification of the putative cinnamyl alcohol dehydrogenase multigene family in Arabidopsis.

Q553P5	STX8A_DICDI	Syntaxin-8A	12175335	Syntaxin 7, syntaxin 8, Vti1 and VAMP7 (vesicle-associated membrane protein 7) form an active SNARE complex for early macropinocytic compartment fusion in Dictyostelium discoideum.

P38696	ARP1_YEAST	Centractin	8069915	A yeast actin-related protein homologous to that in vertebrate dynactin complex is important for spindle orientation and nuclear migration.

P39745	SUR1_CAEEL	Mitogen-activated protein kinase mpk-1	8299936	A MAP kinase homolog, mpk-1, is involved in ras-mediated induction of vulval cell fates in Caenorhabditis elegans.

P48234	NOL10_YEAST	Ribosome biogenesis protein ENP2	15590835	The small-subunit processome is a ribosome assembly intermediate.

P49739	MCM3M_XENLA	Maternal DNA replication licensing factor mcm3	7758114	Identification of the yeast MCM3-related protein as a component of Xenopus DNA replication licensing factor.

Q9NZ20	PA2G3_HUMAN	Group 3 secretory phospholipase A2	10713052	Novel human secreted phospholipase A2 with homology to the group III bee venom enzyme.

Q3UHN9	NDST1_MOUSE	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1	16020517	Cerebral hypoplasia and craniofacial defects in mice lacking heparan sulfate Ndst1 gene function.

P26051	CD44_RAT	CD44 antigen	1707342	A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells.

O95125	ZN202_HUMAN	Zinc finger protein 202	10748193	A broad role for the zinc finger protein ZNF202 in human lipid metabolism.

O35780	BHE40_RAT	Class E basic helix-loop-helix protein 40	9532582	SHARPs: mammalian enhancer-of-split- and hairy-related proteins coupled to neuronal stimulation.

Q07458	RXT3_YEAST	Transcriptional regulatory protein RXT3	14562095	Global analysis of protein localization in budding yeast.

P25293	NAP1_YEAST	Nucleosome assembly protein	2016313	Identification and molecular cloning of yeast homolog of nucleosome assembly protein I which facilitates nucleosome assembly in vitro.

P21333	FLNA_HUMAN	Filamin-A	2391361	Human endothelial actin-binding protein (ABP-280, nonmuscle filamin): a molecular leaf spring.

Q9JIR3	RIMS3_RAT	Regulating synaptic membrane exocytosis protein 3	10748113	The RIM/NIM family of neuronal C2 domain proteins. Interactions with Rab3 and a new class of Src homology 3 domain proteins.

Q08208	NOP12_YEAST	Nucleolar protein 12	11452019	Nucleolar protein Nop12p participates in synthesis of 25S rRNA in Saccharomyces cerevisiae.

O74189	PMT1_CANAL	Dolichyl-phosphate-mannose--protein mannosyltransferase 1	9694829	Multiple functions of Pmt1p-mediated protein O-mannosylation in the fungal pathogen Candida albicans.

Q91372	DDX4_XENLA	Probable ATP-dependent RNA helicase DDX4	8150200	Isolation and characterization of a novel gene of the DEAD box protein family which is specifically expressed in germ cells of Xenopus laevis.

Q92882	OSTF1_HUMAN	Osteoclast-stimulating factor 1	10092216	Isolation and characterization of a cDNA clone encoding a novel peptide (OSF) that enhances osteoclast formation and bone resorption.

Q9R1P4	PSA1_MOUSE	Proteasome subunit alpha type-1	12874245	The proteasome as a lipopolysaccharide-binding protein in macrophages: differential effects of proteasome inhibition on lipopolysaccharide-induced signaling events.

Q9LND1	ERF94_ARATH	Ethylene-responsive transcription factor ERF094	18467450	The AP2/ERF domain transcription factor ORA59 integrates jasmonic acid and ethylene signals in plant defense.

P05388	RLA0_HUMAN	60S acidic ribosomal protein P0	3323886	Human acidic ribosomal phosphoproteins P0, P1, and P2: analysis of cDNA clones, in vitro synthesis, and assembly.

P0CB65	SRRM4_DANRE	Serine/arginine repetitive matrix protein 4	19737518	Regulation of vertebrate nervous system alternative splicing and development by an SR-related protein.

Q9LDR4	ERG24_ARATH	Delta(14)-sterol reductase	10859167	A critical role of sterols in embryonic patterning and meristem programming revealed by the fackel mutants of Arabidopsis thaliana.

O54724	PTRF_MOUSE	Polymerase I and transcript release factor	11139612	The transcript release factor PTRF augments ribosomal gene transcription by facilitating reinitiation of RNA polymerase I.

O43548	TGM5_HUMAN	Protein-glutamine gamma-glutamyltransferase 5	9452468	Isolation of a cDNA encoding a novel member of the transglutaminase gene family from human keratinocytes. Detection and identification of transglutaminase gene products based on reverse transcription- polymerase chain reaction with degenerate primers.

Q9UDW3	ZMAT5_HUMAN	Zinc finger matrin-type protein 5	15146077	The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome.

P40526	DFG10_YEAST	Probable polyprenol reductase	9055077	Dissection of filamentous growth by transposon mutagenesis in Saccharomyces cerevisiae.

O35180	SH3G3_RAT	Endophilin-A3	9238017	The SH3p4/Sh3p8/SH3p13 protein family: binding partners for synaptojanin and dynamin via a Grb2-like Src homology 3 domain.

O60635	TSN1_HUMAN	Tetraspanin-1	9714763	Sequences and expression of six new members of the tetraspanin/TM4SF family.

Q9GQQ0	SPIN_DROME	Protein spinster	15998804	Aberrant lysosomal carbohydrate storage accompanies endocytic defects and neurodegeneration in Drosophila benchwarmer.

Q16698	DECR_HUMAN	2,4-dienoyl-CoA reductase, mitochondrial	7818482	Isolation and characterization of cDNA for human 120 kDa mitochondrial 2,4-dienoyl-coenzyme A reductase.

O13710	SMC5_SCHPO	Structural maintenance of chromosomes protein 5	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O74756	CHS2_SCHPO	Chitin synthase-like protein 2	12914947	In Schizosaccharomyces pombe chs2p has no chitin synthase activity but is related to septum formation.

Q12019	MDN1_YEAST	Midasin	15528184	Rea1, a dynein-related nuclear AAA-ATPase, is involved in late rRNA processing and nuclear export of 60 S subunits.

Q08605	GAGA_DROME	Transcription factor GAGA	10347208	The N-terminal POZ domain of GAGA mediates the formation of oligomers that bind DNA with high affinity and specificity.

Q08649	ESA1_YEAST	Histone acetyltransferase ESA1	10082517	Esa1p is an essential histone acetyltransferase required for cell cycle progression.

P61205	ARF3_MOUSE	ADP-ribosylation factor 3	8947846	Structure and intracellular localization of mouse ADP-ribosylation factors type 1 to type 6 (ARF1-ARF6).

Q62925	M3K1_RAT	Mitogen-activated protein kinase kinase kinase 1	11784851	Direct activation of mitogen-activated protein kinase kinase kinase MEKK1 by the Ste20p homologue GCK and the adapter protein TRAF2.

P55290	CAD13_HUMAN	Cadherin-13	11027617	The glycosyl phosphatidylinositol anchor of human T-cadherin binds lipoproteins.

Q9QXK7	CPSF3_MOUSE	Cleavage and polyadenylation specificity factor subunit 3	18955505	Studies of the 5' exonuclease and endonuclease activities of CPSF-73 in histone pre-mRNA processing.

P61855	AKH_DROME	Adipokinetic hormone	2117437	The fruitfly Drosophila melanogaster contains a novel charged adipokinetic-hormone-family peptide.

Q8IWU6	SULF1_HUMAN	Extracellular sulfatase Sulf-1	12368295	Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans.

Q99726	ZNT3_HUMAN	Zinc transporter 3	8962159	ZnT-3, a putative transporter of zinc into synaptic vesicles.

Q92730	RND1_HUMAN	Rho-related GTP-binding protein Rho6	9531558	A new member of the Rho family, Rnd1, promotes disassembly of actin filament structures and loss of cell adhesion.

Q9U1M8	MYOI_DICDI	Myosin-I heavy chain	15826949	Identification of a myosin VII-talin complex.

P17793	VIRB3_AGRT5	Protein virB3	2233252	Characterization of the virB operon of an Agrobacterium tumefaciens Ti plasmid: nucleotide sequence and protein analysis.

P52285	SKP1A_DICDI	SCF ubiquitin ligase complex protein SKP1a	1577798	Characterization of a cytosolic fucosylation pathway in Dictyostelium.

P33647	CHPB_ECOLI	PemK-like protein 2	8226627	chpA and chpB, Escherichia coli chromosomal homologs of the pem locus responsible for stable maintenance of plasmid R100.

P18583	SON_HUMAN	Protein SON	1944255	Identification of a protein product of a novel human gene SON and the biological effect upon administering a changed form of this gene into mammalian cells.

P89886	TMA20_YEAST	Translation machinery-associated protein 20	16702403	Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes.

O60107	SNX41_SCHPO	Sorting nexin-41	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q94A97	UBC35_ARATH	Ubiquitin-conjugating enzyme E2 35	20113438	A lysine-63-linked ubiquitin chain-forming conjugase, UBC13, promotes the developmental responses to iron deficiency in Arabidopsis roots.

P23501	DS1P2_YEAST	Dihydrosphingosine 1-phosphate phosphatase YSR3	10856228	Sphingoid base synthesis requirement for endocytosis in Saccharomyces cerevisiae.

P25377	ADH7_YEAST	NADP-dependent alcohol dehydrogenase 7	12423374	Characterization of a Saccharomyces cerevisiae NADP(H)-dependent alcohol dehydrogenase (ADHVII), a member of the cinnamyl alcohol dehydrogenase family.

Q9Y6K9	NEMO_HUMAN	NF-kappa-B essential modulator	11418127	CSN3 interacts with IKKgamma and inhibits TNF- but not IL-1-induced NF-kappaB activation.

P84831	TY1_ASCTR	Tryptophyllin-1	15922344	Bradykinin-related peptides and tryptophyllins in the skin secretions of the most primitive extant frog, Ascaphus truei.

P28496	LAC1_YEAST	Sphingosine N-acyltransferase LAC1	11387200	C26-CoA-dependent ceramide synthesis of Saccharomyces cerevisiae is operated by Lag1p and Lac1p.

Q9VRA2	MOCOS_DROME	Molybdenum cofactor sulfurase	11029694	Comparison of the sequences of the Aspergillus nidulans hxB and Drosophila melanogaster ma-l genes with nifS from Azotobacter vinelandii suggests a mechanism for the insertion of the terminal sulphur atom in the molybdopterin cofactor.

Q9VHN9	HPS5_DROME	Hermansky-Pudlak syndrome 5 protein homolog	9714595	Not just pretty eyes: Drosophila eye-colour mutations and lysosomal delivery.

P63279	UBC9_HUMAN	SUMO-conjugating enzyme UBC9	8610150	Mammalian ubiquitin-conjugating enzyme Ubc9 interacts with Rad51 recombination protein and localizes in synaptonemal complexes.

O43915	VEGFD_HUMAN	Vascular endothelial growth factor D	9479493	Human FIGF: cloning, gene structure, and mapping to chromosome Xp22.1 between the PIGA and the GRPR genes.

P49597	P2C56_ARATH	Protein phosphatase 2C 56	12228349	Role of abscisic acid in drought-induced freezing tolerance, cold acclimation, and accumulation of lt178 and rab18 proteins in Arabidopsis thaliana.

Q12039	HMI1_YEAST	ATP-dependent DNA helicase HMI1, mitochondrial	10669756	A DNA helicase required for maintenance of the functional mitochondrial genome in Saccharomyces cerevisiae.

Q9LSW8	ETFB_ARATH	Electron transfer flavoprotein subunit beta, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P47122	NPA3_YEAST	GTPase NPA3	15082539	The identification of Pcl1-interacting proteins that genetically interact with Cla4 may indicate a link between G1 progression and mitotic exit.

P49591	SYSC_HUMAN	Seryl-tRNA synthetase, cytoplasmic	9431993	Genomic organization, cDNA sequence, bacterial expression, and purification of human seryl-tRNA synthase.

Q7Z460	CLAP1_HUMAN	CLIP-associating protein 1	16866869	Mammalian CLASPs are required for mitotic spindle organization and kinetochore alignment.

Q7L5Y9	MAEA_HUMAN	Macrophage erythroblast attacher	9763581	Molecular identification and functional characterization of a novel protein that mediates the attachment of erythroblasts to macrophages.

Q9DCU9	DAPAL_MOUSE	Dihydrodipicolinate synthase-like, mitochondrial	14651853	Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.

Q9USP2	YND1_SCHPO	Golgi apyrase	12686557	Nucleoside diphosphatase and glycosyltransferase activities can localize to different subcellular compartments in Schizosaccharomyces pombe.

O97902	ASAP1_BOVIN	Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1	9819391	ASAP1, a phospholipid-dependent arf GTPase-activating protein that associates with and is phosphorylated by Src.

P09012	SNRPA_HUMAN	U1 small nuclear ribonucleoprotein A	9848648	The snRNP-free U1A (SF-A) complex(es): identification of the largest subunit as PSF, the polypyrimidine-tract binding protein-associated splicing factor.

P40573	MET28_YEAST	Transcriptional activator of sulfur metabolism MET28	14562095	Global analysis of protein localization in budding yeast.

P77581	ASTC_ECOLI	Succinylornithine transaminase	9696779	Arginine catabolism and the arginine succinyltransferase pathway in Escherichia coli.

Q9JHE4	G3ST1_MOUSE	Galactosylceramide sulfotransferase	11917099	Paranodal junction formation and spermatogenesis require sulfoglycolipids.

Q8R4Z1	SPA12_RAT	Serpin A12	16030142	Visceral adipose tissue-derived serine protease inhibitor: a unique insulin-sensitizing adipocytokine in obesity.

Q12926	ELAV2_HUMAN	ELAV-like protein 2	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

Q8T9S7	PTEN_DICDI	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	17623773	PTEN plays a role in the suppression of lateral pseudopod formation during Dictyostelium motility and chemotaxis.

Q15080	NCF4_HUMAN	Neutrophil cytosol factor 4	8839867	Genomic structure, chromosomal localization, start of transcription, and tissue expression of the human p40-phox, a new component of the nicotinamide adenine dinucleotide phosphate-oxidase complex.

Q9DC77	SMPX_MOUSE	Small muscular protein	11381084	The small muscle-specific protein Csl modifies cell shape and promotes myocyte fusion in an insulin-like growth factor 1-dependent manner.

P97767	EYA1_MOUSE	Eyes absent homolog 1	14628052	Eyes absent represents a class of protein tyrosine phosphatases.

Q13573	SNW1_HUMAN	SNW domain-containing protein 1	15194481	The human Ski-interacting protein functionally substitutes for the yeast PRP45 gene.

Q32SG4	WRKY1_MAIZE	Protein WRKY1	16243907	Maize rough sheath2 and its Arabidopsis orthologue ASYMMETRIC LEAVES1 interact with HIRA, a predicted histone chaperone, to maintain knox gene silencing and determinacy during organogenesis.

Q9LQT8	GAI_ARATH	DELLA protein GAI	12492836	Evidence that the Arabidopsis nuclear gibberellin signalling protein GAI is not destabilised by gibberellin.

Q8BVK9	SP110_MOUSE	Sp110 nuclear body protein	15815631	Ipr1 gene mediates innate immunity to tuberculosis.

Q00978	IRF9_HUMAN	Interferon regulatory factor 9	1630447	Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA- binding proteins.

P01210	PENK_HUMAN	Proenkephalin-A	7057924	Primary structure of the human Met- and Leu-enkephalin precursor and its mRNA.

Q9EQF6	DPYL5_MOUSE	Dihydropyrimidinase-related protein 5	10956643	Molecular characterization of CRMP5, a novel member of the collapsin response mediator protein family.

Q12071	VPS54_YEAST	Vacuolar protein sorting-associated protein 54	12620189	The ARF-like GTPases Arl1p and Arl3p act in a pathway that interacts with vesicle-tethering factors at the Golgi apparatus.

P32368	SAC1_YEAST	Phosphoinositide phosphatase SAC1	11514624	Sac1 lipid phosphatase and Stt4 phosphatidylinositol 4-kinase regulate a pool of phosphatidylinositol 4-phosphate that functions in the control of the actin cytoskeleton and vacuole morphology.

Q9LDF1	CINS_ARATH	1,8-cineole synthase, chloroplastic	15299125	Characterization of a root-specific Arabidopsis terpene synthase responsible for the formation of the volatile monoterpene 1,8- cineole.

Q9I7U4	TITIN_DROME	Titin	11062264	D-Titin: a giant protein with dual roles in chromosomes and muscles.

P00507	AATM_RAT	Aspartate aminotransferase, mitochondrial	11962739	Immunogold localization of mitochondrial aspartate aminotransferase in mitochondria and on the cell surface in normal rat tissues.

O60907	TBL1X_HUMAN	F-box-like/WD repeat-containing protein TBL1X	10809664	A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40- repeat protein linked to deafness.

Q9SB58	ZDH19_ARATH	Probable S-acyltransferase At4g24630	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q7M6Y2	SOX11_MOUSE	Transcription factor SOX-11	15456859	Interplay of SOX and POU factors in regulation of the nestin gene in neural primordial cells.

P47154	STE24_YEAST	CAAX prenyl protease 1	9065405	Modulation of Ras and a-factor function by carboxyl-terminal proteolysis.

Q9NAD6	STAT1_CAEEL	Signal transducer and activator of transcription 1	16401427	C. elegans STAT cooperates with DAF-7/TGF-beta signaling to repress dauer formation.

Q99675	CGRF1_HUMAN	Cell growth regulator with RING finger domain protein 1	8968090	Induction of cell growth regulatory genes by p53.

Q8BHY3	ANO1_MOUSE	Anoctamin-1	18585372	The transmembrane protein TMEM16A is required for normal development of the murine trachea.

P13861	KAP2_HUMAN	cAMP-dependent protein kinase type II-alpha regulatory subunit	2540040	Human testis cDNA for the regulatory subunit RII alpha of cAMP- dependent protein kinase encodes an alternate amino-terminal region.

O49562	PDRP1_ARATH	Pyruvate, phosphate dikinase regulatory protein 1, chloroplastic	17996018	The pyruvate, orthophosphate dikinase regulatory proteins of Arabidopsis possess a novel, unprecedented Ser/Thr protein kinase primary structure.

P31315	GSX1_MOUSE	GS homeobox 1	8631293	Gsh-1, an orphan Hox gene, is required for normal pituitary development.

O54963	REST_RAT	RE1-silencing transcription factor	9454838	Neuronal expression of zinc finger transcription factor REST/NRSF/XBR gene.

Q9ATB4	TAD2B_ARATH	Transcriptional adapter ADA2b	16603259	Physical and functional interactions of Arabidopsis ADA2 transcriptional coactivator proteins with the acetyltransferase GCN5 and with the cold-induced transcription factor CBF1.

O76075	DFFB_HUMAN	DNA fragmentation factor subunit beta	9671700	The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis.

P22579	SIN3_YEAST	Transcriptional regulatory protein SIN3	16286008	Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex.

P35908	K22E_HUMAN	Keratin, type II cytoskeletal 2 epidermal	7524919	Mutations in the rod domain of keratin 2e in patients with ichthyosis bullosa of Siemens.

Q11094	TWIST_CAEEL	Twist-related protein	9716413	Analysis of a Caenorhabditis elegans Twist homolog identifies conserved and divergent aspects of mesodermal patterning.

P54362	AP3D_DROME	AP-3 complex subunit delta	9303295	Altered expression of a novel adaptin leads to defective pigment granule biogenesis in the Drosophila eye color mutant garnet.

Q9FJV8	PEN5_ARATH	Marneral synthase	16425307	An Arabidopsis oxidosqualene cyclase catalyzes iridal skeleton formation by Grob fragmentation.

Q00645	PLYB_EMENI	Pectate lyase plyB	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

O75161	NPHP4_HUMAN	Nephrocystin-4	12205563	A gene mutated in nephronophthisis and retinitis pigmentosa encodes a novel protein, nephroretinin, conserved in evolution.

P09032	EI2BG_YEAST	Translation initiation factor eIF-2B subunit gamma	8506384	A protein complex of translational regulators of GCN4 mRNA is the guanine nucleotide-exchange factor for translation initiation factor 2 in yeast.

Q14103	HNRPD_HUMAN	Heterogeneous nuclear ribonucleoprotein D0	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

P18102	TLL_DROME	Protein tailless	10357938	The control of cell fate in the embryonic visual system by atonal, tailless and EGFR signaling.

Q15691	MARE1_HUMAN	Microtubule-associated protein RP/EB family member 1	11943150	Involvement of the telomeric protein Pin2/TRF1 in the regulation of the mitotic spindle.

O04719	P2C77_ARATH	Protein phosphatase 2C 77	11208021	The ABI1 and ABI2 protein phosphatases 2C act in a negative feedback regulatory loop of the abscisic acid signalling pathway.

Q9LIA4	RIK_ARATH	Protein RIK	16243907	Maize rough sheath2 and its Arabidopsis orthologue ASYMMETRIC LEAVES1 interact with HIRA, a predicted histone chaperone, to maintain knox gene silencing and determinacy during organogenesis.

P86100	HYAL1_MESMA	Hyaluronidase-1	18611448	Isolation and characterization of a hyaluronidase from the venom of Chinese red scorpion Buthus martensi.

Q9GPM2	PCP_DICDI	Paracaspase	17889831	Autophagic or necrotic cell death in the absence of caspase and bcl-2 family members.

P32558	SPT16_YEAST	FACT complex subunit SPT16	15987999	The yeast FACT complex has a role in transcriptional initiation.

O75381	PEX14_HUMAN	Peroxisomal membrane protein PEX14	19197237	Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19.

Q9LU77	PIN2_ARATH	Auxin efflux carrier component 2	9844024	The Arabidopsis thaliana AGRAVITROPIC 1 gene encodes a component of the polar-auxin-transport efflux carrier.

P38196	FUI1_YEAST	Uridine permease	10827169	Nucleoside transporter proteins of Saccharomyces cerevisiae. Demonstration of a transporter (FUI1) with high uridine selectivity in plasma membranes and a transporter (FUN26) with broad nucleoside selectivity in intracellular membranes.

Q9UKA1	FBXL5_HUMAN	F-box/LRR-repeat protein 5	17532294	FBXL5 interacts with p150Glued and regulates its ubiquitination.

P40692	MLH1_HUMAN	DNA mismatch repair protein Mlh1	14676842	Characterization of human exonuclease 1 in complex with mismatch repair proteins, subcellular localization and association with PCNA.

P35169	TOR1_YEAST	Serine/threonine-protein kinase TOR1	10329624	Tor proteins and protein phosphatase 2A reciprocally regulate Tap42 in controlling cell growth in yeast.

C6KTD2	HKNMT_PLAF7	Putative histone-lysine N-methyltransferase PFF1440w	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

O95238	SPDEF_HUMAN	SAM pointed domain-containing Ets transcription factor	10625666	PDEF, a novel prostate epithelium-specific ets transcription factor, interacts with the androgen receptor and activates prostate-specific antigen gene expression.

P32248	CCR7_HUMAN	C-C chemokine receptor type 7	8383238	Epstein-Barr virus-induced genes: first lymphocyte-specific G protein-coupled peptide receptors.

P70399	TP53B_MOUSE	Tumor suppressor p53-binding protein 1	11801725	Kinetochore localisation of the DNA damage response component 53BP1 during mitosis.

Q943E9	HS17B_ORYSJ	17.9 kDa heat shock protein 2	15803416	Characterization of the genomic structures and selective expression profiles of nine class I small heat shock protein genes clustered on two chromosomes in rice (Oryza sativa L.).

Q8N4H5	TOM5_HUMAN	Mitochondrial import receptor subunit TOM5 homolog	18331822	Identification of Tom5 and Tom6 in the preprotein translocase complex of human mitochondrial outer membrane.

Q25619	FAR1_ONCVO	Fatty-acid and retinol-binding protein 1	10693749	The secretory Onchocerca volvulus protein OvS1/Ov20 exhibits the capacity to compete with serum albumin for the host's long-chain fatty acids.

Q05778	POC1_YEAST	Proteasome chaperone 1	14562095	Global analysis of protein localization in budding yeast.

Q09811	HUS2_SCHPO	ATP-dependent DNA helicase hus2/rqh1	12724426	Role for the fission yeast RecQ helicase in DNA repair in G2.

O95944	NCTR2_HUMAN	Natural cytotoxicity triggering receptor 2	10049942	NKp44, a triggering receptor involved in tumor cell lysis by activated human natural killer cells, is a novel member of the immunoglobulin superfamily.

P30988	CALCR_HUMAN	Calcitonin receptor	1331173	Cloning, characterization, and expression of a human calcitonin receptor from an ovarian carcinoma cell line.

Q9FLG1	BXL4_ARATH	Beta-D-xylosidase 4	15593128	Cell wall proteins in apoplastic fluids of Arabidopsis thaliana rosettes: identification by mass spectrometry and bioinformatics.

P41912	ERFD_YEAST	Ras modification protein ERF4	12379641	Erf4p and Erf2p form an endoplasmic reticulum-associated complex involved in the plasma membrane localization of yeast Ras proteins.

Q9JK15	ADAP2_RAT	Arf-GAP with dual PH domain-containing protein 2	12018390	Identification of centaurin-alpha2: a phosphatidylinositide-binding protein present in fat, heart and skeletal muscle.

P32302	CXCR5_HUMAN	C-X-C chemokine receptor type 5	9463416	B cell-attracting chemokine 1, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5.

Q9EPT5	SO2A1_MOUSE	Solute carrier organic anion transporter family member 2A1	10484490	Cloning of mouse prostaglandin transporter PGT cDNA: species-specific substrate affinities.

P38843	CHS7_YEAST	Chitin synthase export chaperone	10366589	Chs7p, a new protein involved in the control of protein export from the endoplasmic reticulum that is specifically engaged in the regulation of chitin synthesis in Saccharomyces cerevisiae.

Q7TN39	MRGRG_RAT	Mas-related G-protein coupled receptor member G	12909716	Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family.

Q9M3G7	ATM_ARATH	Serine/threonine-protein kinase ATM	12509526	AtATM is essential for meiosis and the somatic response to DNA damage in plants.

P32389	MET4_YEAST	Transcriptional activator of sulfur metabolism MET4	1549123	MET4, a leucine zipper protein, and centromere-binding factor 1 are both required for transcriptional activation of sulfur metabolism in Saccharomyces cerevisiae.

Q92890	UFD1_HUMAN	Ubiquitin fusion degradation protein 1 homolog	9063746	UFD1L, a developmentally expressed ubiquitination gene, is deleted in CATCH 22 syndrome.

P53076	VID30_YEAST	Vacuolar import and degradation protein 30	14562095	Global analysis of protein localization in budding yeast.

Q6RI88	S4A5_RAT	Electrogenic sodium bicarbonate cotransporter 4	15151908	Expression and localization of rat NBC4c in liver and renal uroepithelium.

O94444	RPN10_SCHPO	26S proteasome regulatory subunit rpn10	12560082	Ubiquitin binding proteins protect ubiquitin conjugates from disassembly.

O76081	RGS20_HUMAN	Regulator of G-protein signaling 20	9748279	RGSZ1, a Gz-selective regulator of G protein signaling whose action is sensitive to the phosphorylation state of Gzalpha.

P42345	MTOR_HUMAN	Serine/threonine-protein kinase mTOR	19446321	DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival.

Q9H089	LSG1_HUMAN	Large subunit GTPase 1 homolog	16209721	Human Lsg1 defines a family of essential GTPases that correlates with the evolution of compartmentalization.

P20933	ASPG_HUMAN	N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	8776587	Ser72-->Pro active-site disease mutation in human lysosomal aspartylglucosaminidase: abnormal intracellular processing and evidence for extracellular activation.

Q7YU29	DMDE_DROME	Dystrophin, isoform E	17543506	Drosophila Dystrophin is required for integrity of the musculature.

P68036	UB2L3_HUMAN	Ubiquitin-conjugating enzyme E2 L3	17003263	UbcH7 interacts with the glucocorticoid receptor and mediates receptor autoregulation.

P0C2H4	DSE_BOVIN	Dermatan-sulfate epimerase	16505484	Biosynthesis of dermatan sulfate: chondroitin-glucuronate C5- epimerase is identical to SART2.

P29460	IL12B_HUMAN	Interleukin-12 subunit beta	10899108	Charged residues dominate a unique interlocking topography in the heterodimeric cytokine interleukin-12.

Q8TBC4	UBA3_HUMAN	NEDD8-activating enzyme E1 catalytic subunit	15361859	A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8.

Q9WVP6	PAPOB_MOUSE	Poly(A) polymerase beta	18325338	Germ cell-specific gene 1 targets testis-specific poly(A) polymerase to the endoplasmic reticulum through protein-protein interactions.

P43585	VTC2_YEAST	Vacuolar transporter chaperone 2	11823419	The Vtc proteins in vacuole fusion: coupling NSF activity to V(0) trans-complex formation.

Q9Y5Y5	PEX16_HUMAN	Peroxisomal membrane protein PEX16	12223482	The membrane biogenesis peroxin Pex16p. Topogenesis and functional roles in peroxisomal membrane assembly.

Q86IL5	PP4R2_DICDI	Serine/threonine-protein phosphatase 4 regulatory subunit 2	17353263	MEK1 and protein phosphatase 4 coordinate Dictyostelium development and chemotaxis.

Q9SCT4	IMK2_ARATH	Probably inactive leucine-rich repeat receptor-like protein kinase IMK2	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q64695	EPCR_MOUSE	Endothelial protein C receptor	10235444	Nucleotide structure and characterization of the murine gene encoding the endothelial cell protein C receptor.

Q03516	RSN1_YEAST	Uncharacterized protein RSN1	17005914	The yeast tumor suppressor homologue Sro7p is required for targeting of the sodium pumping ATPase to the cell surface.

Q25619	FAR1_ONCVO	Fatty-acid and retinol-binding protein 1	7770083	Characterisation of an immunodominant glycoprotein antigen of Onchocerca volvulus with homologues in other filarial nematodes and Caenorhabditis elegans.

Q91VN0	LRP5_MOUSE	Low-density lipoprotein receptor-related protein 5	15142971	The Wnt co-receptors Lrp5 and Lrp6 are essential for gastrulation in mice.

Q03898	FIN1_YEAST	Filament protein FIN1	12551942	Self-association of the spindle pole body-related intermediate filament protein Fin1p and its phosphorylation-dependent interaction with 14-3-3 proteins in yeast.

P42208	SEPT2_MOUSE	Septin-2	11739749	The septin CDCrel-1 is dispensable for normal development and neurotransmitter release.

Q08907	FIT3_YEAST	Facilitator of iron transport 3	10383953	Amino acid residues in the omega-minus region participate in cellular localization of yeast glycosylphosphatidylinositol-attached proteins.

Q9QZZ4	MYO15_MOUSE	Myosin-XV	15654330	Myosin-XVa is required for tip localization of whirlin and differential elongation of hair-cell stereocilia.

P49327	FAS_HUMAN	Fatty acid synthase	7567999	Human fatty acid synthase: properties and molecular cloning.

O88881	BEGIN_RAT	Brain-enriched guanylate kinase-associated protein	9756850	BEGAIN (brain-enriched guanylate kinase-associated protein), a novel neuronal PSD-95/SAP90-binding protein.

Q9LD43	ACCA_ARATH	Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, chloroplastic	16207701	The oligomeric stromal proteome of Arabidopsis thaliana chloroplasts.

P05554	CEBPA_RAT	CCAAT/enhancer-binding protein alpha	2850264	Isolation of a recombinant copy of the gene encoding C/EBP.

Q9ERE3	SGK3_MOUSE	Serine/threonine-protein kinase Sgk3	11050396	Identification of CISK, a new member of the SGK kinase family that promotes IL-3-dependent survival.

Q9NQ66	PLCB1_HUMAN	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1	12799190	Diacylglycerol kinase-theta is localized in the speckle domains of the nucleus.

Q9UBQ7	GRHPR_HUMAN	Glyoxylate reductase/hydroxypyruvate reductase	10524214	Identification and expression of a cDNA for human hydroxypyruvate/glyoxylate reductase.

Q80U87	UBP8_MOUSE	Ubiquitin carboxyl-terminal hydrolase 8	10982817	A deubiquitinating enzyme UBPY interacts with the Src homology 3 domain of Hrs-binding protein via a novel binding motif PX(V/I)(D/N)RXXKP.

Q54QT9	CBPF_DICDI	Calcium-binding protein F	14706075	Identification and characterization of novel calcium-binding proteins of Dictyostelium and their spatial expression patterns during development.

Q9NUW8	TYDP1_HUMAN	Tyrosyl-DNA phosphodiesterase 1	12023295	Conversion of phosphoglycolate to phosphate termini on 3' overhangs of DNA double strand breaks by the human tyrosyl-DNA phosphodiesterase hTdp1.

P17302	CXA1_HUMAN	Gap junction alpha-1 protein	1696265	Molecular characterization and functional expression of the human cardiac gap junction channel.

Q12794	HYAL1_HUMAN	Hyaluronidase-1	9223416	Purification, cloning, and expression of human plasma hyaluronidase.

O13024	INCEA_XENLA	Inner centromere protein A	12464631	Cohesin release is required for sister chromatid resolution, but not for condensin-mediated compaction, at the onset of mitosis.

Q9JII1	INP5E_MOUSE	72 kDa inositol polyphosphate 5-phosphatase	10806194	Cloning and characterization of a 72-kDa inositol-polyphosphate 5- phosphatase localized to the Golgi network.

Q08605	GAGA_DROME	Transcription factor GAGA	12815073	Drosophila FACT contributes to Hox gene expression through physical and functional interactions with GAGA factor.

O08653	TEP1_RAT	Telomerase protein component 1	10864046	RNA location and modeling of a WD40 repeat domain within the vault.

O75581	LRP6_HUMAN	Low-density lipoprotein receptor-related protein 6	9704021	Isolation and characterization of LRP6, a novel member of the low density lipoprotein receptor gene family.

D2EAC2	ZBED6_MOUSE	Zinc finger BED domain-containing protein 6	20016685	ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth.

P84262	PA3B_RANPA	Palustrin-3b	11087945	Multiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris.

P39006	PSD1_YEAST	Phosphatidylserine decarboxylase proenzyme 1, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

O88552	CLD2_MOUSE	Claudin-2	10508613	Ca(2+)-independent cell-adhesion activity of claudins, a family of integral membrane proteins localized at tight junctions.

Q92759	TF2H4_HUMAN	General transcription factor IIH subunit 4	9852112	Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.

Q12396	EMP46_YEAST	Protein EMP46	12857885	Oligomerization of a cargo receptor directs protein sorting into COPII-coated transport vesicles.

P56721	COLL_DROME	Transcription factor collier	10477305	Head versus trunk patterning in the Drosophila embryo; collier requirement for formation of the intercalary segment.

O16850	FOXO_CAEEL	Forkhead box protein O	17934462	DAF-16/FOXO targets genes that regulate tumor growth in Caenorhabditis elegans.

Q9H0M0	WWP1_HUMAN	NEDD4-like E3 ubiquitin-protein ligase WWP1	12535537	Conformational flexibility underlies ubiquitin ligation mediated by the WWP1 HECT domain E3 ligase.

P19938	DAAA_BACYM	D-alanine aminotransferase	7626635	Crystal structure of a D-amino acid aminotransferase: how the protein controls stereoselectivity.

Q07963	UBR2_YEAST	E3 ubiquitin-protein ligase UBR2	14562095	Global analysis of protein localization in budding yeast.

O73622	PAT_XENLA	Protein Pat	11784096	Three-dimensional ultrastructural analysis of RNA distribution within germinal granules of Xenopus.

Q9US37	YFZ4_SCHPO	Uncharacterized transporter C1039.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q4KMQ1	TPRN_HUMAN	Taperin	20170899	Targeted capture and next-generation sequencing identifies C9orf75, encoding taperin, as the mutated gene in nonsyndromic deafness DFNB79.

P42685	FRK_HUMAN	Tyrosine-protein kinase FRK	7696183	Rak, a novel nuclear tyrosine kinase expressed in epithelial cells.

Q60760	GRB10_MOUSE	Growth factor receptor-bound protein 10	17376403	GRB10 binds to LRP6, the Wnt co-receptor and inhibits canonical Wnt signaling pathway.

P10659	METK1_YEAST	S-adenosylmethionine synthase 1	3316224	SAM1, the structural gene for one of the S-adenosylmethionine synthetases in Saccharomyces cerevisiae. Sequence and expression.

O60673	DPOLZ_HUMAN	DNA polymerase zeta catalytic subunit	9618506	A human homolog of the Saccharomyces cerevisiae REV3 gene, which encodes the catalytic subunit of DNA polymerase zeta.

O94673	YG75_SCHPO	Uncharacterized membrane protein C776.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P51532	SMCA4_HUMAN	Transcription activator BRG1	8208605	Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor.

Q8WV28	BLNK_HUMAN	B-cell linker protein	9341187	Identification of two tyrosine phosphoproteins, pp70 and pp68, which interact with phospholipase Cgamma, Grb2, and Vav after B cell antigen receptor activation.

P53923	CTU2_YEAST	Cytoplasmic tRNA 2-thiolation protein 2	19151091	Mechanistic characterization of the sulfur-relay system for eukaryotic 2-thiouridine biogenesis at tRNA wobble positions.

P05756	RS13_YEAST	40S ribosomal protein S13	6814480	Isolation of seventeen proteins and amino-terminal amino acid sequences of eight proteins from cytoplasmic ribosomes of yeast.

Q84WM7	PPME1_ARATH	Pectinesterase PPME1	16564517	Pollen-specific pectin methylesterase involved in pollen tube growth.

Q94C59	PATL4_ARATH	Patellin-4	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P49450	CENPA_HUMAN	Histone H3-like centromeric protein A	7962047	Human CENP-A contains a histone H3 related histone fold domain that is required for targeting to the centromere.

P53930	AF9_YEAST	Protein AF-9 homolog	15485911	The Yaf9 component of the SWR1 and NuA4 complexes is required for proper gene expression, histone H4 acetylation, and Htz1 replacement near telomeres.

P97496	SMRC1_MOUSE	SWI/SNF complex subunit SMARCC1	17640523	An essential switch in subunit composition of a chromatin remodeling complex during neural development.

Q92791	SC65_HUMAN	Synaptonemal complex protein SC65	8862517	cDNA cloning and characterization of a novel nucleolar protein.

Q13651	I10R1_HUMAN	Interleukin-10 receptor subunit alpha	15837194	Same structure, different function crystal structure of the Epstein- Barr virus IL-10 bound to the soluble IL-10R1 chain.

Q7QCC7	OR7_ANOGA	Gustatory and odorant receptor 7	15037749	A highly conserved candidate chemoreceptor expressed in both olfactory and gustatory tissues in the malaria vector Anopheles gambiae.

Q9VEC1	MED17_DROME	Mediator of RNA polymerase II transcription subunit 17	11090137	Drosophila homologs of transcriptional mediator complex subunits are required for adult cell and segment identity specification.

Q9UNA4	POLI_HUMAN	DNA polymerase iota	10458907	Novel human and mouse homologs of Saccharomyces cerevisiae DNA polymerase eta.

P51521	OVO_DROME	Protein ovo	10421370	ovo/svb integrates Wingless and DER pathways to control epidermis differentiation.

Q925G0	RBM3_RAT	Putative RNA-binding protein 3	15684048	Cold stress-induced protein Rbm3 binds 60S ribosomal subunits, alters microRNA levels, and enhances global protein synthesis.

P62997	TRA2B_RAT	Transformer-2 protein homolog beta	7499316	Cloning of a novel RNA binding polypeptide (RA301) induced by hypoxia/reoxygenation.

P38174	AMPM2_YEAST	Methionine aminopeptidase 2	8618900	Amino-terminal protein processing in Saccharomyces cerevisiae is an essential function that requires two distinct methionine aminopeptidases.

O60271	JIP4_HUMAN	C-Jun-amino-terminal kinase-interacting protein 4	9480848	Cloning of a novel human testis mRNA specifically expressed in testicular haploid germ cells, having unique palindromic sequences and encoding a leucine zipper dimerization motif.

Q8K2X3	STN1_MOUSE	CST complex subunit STN1	19648609	OB fold-containing protein 1 (OBFC1), a human homolog of yeast Stn1, associates with TPP1 and is implicated in telomere length regulation.

Q6PJG6	BAAT1_HUMAN	BRCA1-associated protein required for ATM activation protein 1	16452482	ATM activation by ionizing radiation requires BRCA1-associated BAAT1.

Q0D840	TRXH1_ORYSJ	Thioredoxin H1	7766047	Thioredoxin h is one of the major proteins in rice phloem sap.

Q15366	PCBP2_HUMAN	Poly(rC)-binding protein 2	19881509	PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4.

Q8NHU3	SMS2_HUMAN	Phosphatidylcholine:ceramide cholinephosphotransferase 2	14685263	Identification of a family of animal sphingomyelin synthases.

Q8LBP4	ALB3_ARATH	Inner membrane protein ALBINO3, chloroplastic	9165749	ALBINO3, an Arabidopsis nuclear gene essential for chloroplast differentiation, encodes a chloroplast protein that shows homology to proteins present in bacterial membranes and yeast mitochondria.

P93032	IDH2_ARATH	Isocitrate dehydrogenase [NAD] regulatory subunit 2, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P61916	NPC2_HUMAN	Epididymal secretory protein E1	11125141	Identification of HE1 as the second gene of Niemann-Pick C disease.

P25555	GBP2_YEAST	Single-strand telomeric DNA-binding protein GBP2	7777547	A class of single-stranded telomeric DNA-binding proteins required for Rap1p localization in yeast nuclei.

Q8N6M6	AMPO_HUMAN	Aminopeptidase O	15687497	Identification of human aminopeptidase O, a novel metalloprotease with structural similarity to aminopeptidase B and leukotriene A4 hydrolase.

Q8NHH9	ATLA2_HUMAN	Atlastin-2	19665976	A class of dynamin-like GTPases involved in the generation of the tubular ER network.

P24941	CDK2_HUMAN	Cell division protein kinase 2	11980914	Human Speedy: a novel cell cycle regulator that enhances proliferation through activation of Cdk2.

Q02643	GHRHR_HUMAN	Growth hormone-releasing hormone receptor	7680413	Molecular cloning and expression of a human anterior pituitary receptor for growth hormone-releasing hormone.

P36147	PAM17_YEAST	Presequence translocated-associated motor subunit PAM17, mitochondrial	16107694	Pam17 is required for architecture and translocation activity of the mitochondrial protein import motor.

Q8LF80	CKB21_ARATH	Cyclin-dependent kinase B2-1	12857813	Arabidopsis D-type cyclin CYCD4;1 is a novel cyclin partner of B2- type cyclin-dependent kinase.

Q21502	MEP1_CAEEL	MOG interacting and ectopic P-granules protein 1	12507426	MEP-1 and a homolog of the NURD complex component Mi-2 act together to maintain germline-soma distinctions in C. elegans.

Q7ZT46	PSF2_XENLA	DNA replication complex GINS protein PSF2	12730133	A novel ring-like complex of Xenopus proteins essential for the initiation of DNA replication.

Q12167	YD065_YEAST	Uncharacterized protein YDR065W	16168084	Characterization of the yeast ionome: a genome-wide analysis of nutrient mineral and trace element homeostasis in Saccharomyces cerevisiae.

P01213	PDYN_HUMAN	Proenkephalin-B	9047294	NMR and structural model of dynorphin A (1-17) bound to dodecylphosphocholine micelles.

Q95V25	SLO1_CAEEL	Calcium-activated potassium channel slo-1	11738032	SLO-1 potassium channels control quantal content of neurotransmitter release at the C. elegans neuromuscular junction.

Q86XR8	CEP57_HUMAN	Centrosomal protein of 57 kDa	14654843	Proteomic characterization of the human centrosome by protein correlation profiling.

Q9VIQ0	SNPF_DROME	Short neuropeptide F	12171930	Peptidomics of the larval Drosophila melanogaster central nervous system.

Q9STP8	ACBP2_ARATH	Acyl-CoA-binding domain-containing protein 2	15604682	ACBP4 and ACBP5, novel Arabidopsis acyl-CoA-binding proteins with kelch motifs that bind oleoyl-CoA.

Q64127	TIF1A_MOUSE	Transcription intermediary factor 1-alpha	7744009	The N-terminal part of TIF1, a putative mediator of the ligand- dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18.

P54218	SPE27_CAEEL	Spermatocyte protein spe-27	8722776	Genetic and molecular analysis of spe-27, a gene required for spermiogenesis in Caenorhabditis elegans hermaphrodites.

P56508	SNA2_YEAST	Protein SNA2	14562095	Global analysis of protein localization in budding yeast.

P11632	NHP6A_YEAST	Non-histone chromosomal protein 6A	7721780	DNA looping by Saccharomyces cerevisiae high mobility group proteins NHP6A/B. Consequences for nucleoprotein complex assembly and chromatin condensation.

P09493	TPM1_HUMAN	Tropomyosin alpha-1 chain	11273725	Mutations that alter the surface charge of alpha-tropomyosin are associated with dilated cardiomyopathy.

Q9NYA1	SPHK1_HUMAN	Sphingosine kinase 1	10947957	Human sphingosine kinase: purification, molecular cloning and characterization of the native and recombinant enzymes.

P39069	KAD1_RAT	Adenylate kinase isoenzyme 1	8468325	Tissue-specific and developmentally regulated expression of the genes encoding adenylate kinase isozymes.

Q91ZD4	VANG2_MOUSE	Vang-like protein 2	15637299	Vangl2 acts via RhoA signaling to regulate polarized cell movements during development of the proximal outflow tract.

P40092	SPI1_YEAST	Uncharacterized cell wall protein SPI1	16980434	The SPI1 gene, encoding a glycosylphosphatidylinositol-anchored cell wall protein, plays a prominent role in the development of yeast resistance to lipophilic weak-acid food preservatives.

Q99380	OST4_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST4	16297388	Yeast oligosaccharyltransferase consists of two functionally distinct sub-complexes, specified by either the Ost3p or Ost6p subunit.

Q55EU6	ACT23_DICDI	Putative actin-23	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q94BZ7	GYRBM_ARATH	DNA gyrase subunit B, mitochondrial	15136745	Arabidopsis thaliana DNA gyrase is targeted to chloroplasts and mitochondria.

P83142	AFP2S_MALPA	Antifungal protein 2 small subunit	11118343	Potent heterologous antifungal proteins from cheeseweed (Malva parviflora).

P86029	HQD2_CANAL	Catechol 1,2-dioxygenase	17089147	Purification and characterization of a catechol 1,2-dioxygenase from a phenol degrading Candida albicans TL3.

P10499	KCNA1_RAT	Potassium voltage-gated channel subfamily A member 1	10884227	Structure of the cytoplasmic beta subunit-T1 assembly of voltage- dependent K+ channels.

P19262	ODO2_YEAST	Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial	2115121	Structure and regulation of KGD2, the structural gene for yeast dihydrolipoyl transsuccinylase.

Q8CGU4	AGAP2_RAT	Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2	11136977	PIKE: a nuclear GTPase that enhances PI3kinase activity and is regulated by protein 4.1N.

P22815	BOSS_DROME	Protein bride of sevenless	1857416	Interaction of bride of sevenless membrane-bound ligand and the sevenless tyrosine-kinase receptor.

Q99383	HRP1_YEAST	Nuclear polyadenylated RNA-binding protein 4	9334319	Hrp1, a sequence-specific RNA-binding protein that shuttles between the nucleus and the cytoplasm, is required for mRNA 3'-end formation in yeast.

P59226	H32_ARATH	Histone H3.2	17242155	VIM1, a methylcytosine-binding protein required for centromeric heterochromatinization.

Q00799	RBP2_PLAVB	Reticulocyte-binding protein 2	1617731	A reticulocyte-binding protein complex of Plasmodium vivax merozoites.

P13001	BIOH_ECOLI	Carboxylesterase BioH	11904168	Purification and characterisation of the BIOH protein from the biotin biosynthetic pathway.

Q8N137	CNTRB_HUMAN	Centrobin	11984006	The Chediak-Higashi protein interacts with SNARE complex and signal transduction proteins.

Q02643	GHRHR_HUMAN	Growth hormone-releasing hormone receptor	1333056	Molecular cloning and expression of a pituitary-specific receptor for growth hormone-releasing hormone.

O35400	ST2B1_MOUSE	Sulfotransferase family cytosolic 2B member 1	9647753	Molecular cloning, expression, and functional characterization of novel mouse sulfotransferases.

Q64249	NR6A1_MOUSE	Nuclear receptor subfamily 6 group A member 1	7835709	RTR: a new member of the nuclear receptor superfamily that is highly expressed in murine testis.

P48612	PELO_DROME	Protein pelota	16280348	Pelota controls self-renewal of germline stem cells by repressing a Bam-independent differentiation pathway.

Q05431	APX1_ARATH	L-ascorbate peroxidase 1, cytosolic	9808745	The heat-shock element is a functional component of the Arabidopsis APX1 gene promoter.

O00623	PEX12_HUMAN	Peroxisome assembly protein 12	10704444	PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis.

P41838	RAE1_SCHPO	Poly(A)+ RNA export protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8RXS6	INO80_ARATH	DNA helicase INO80 complex homolog 1	15525519	The INO80 protein controls homologous recombination in Arabidopsis thaliana.

P19338	NUCL_HUMAN	Nucleolin	2394707	Genomic organization and chromosomal localization of the human nucleolin gene.

Q04401	ACN9_YEAST	Acetate non-utilizing protein 9, mitochondrial	8878673	Mutants of Saccharomyces cerevisiae with defects in acetate metabolism: isolation and characterization of Acn- mutants.

O60481	ZIC3_HUMAN	Zinc finger protein ZIC 3	9354794	X-linked situs abnormalities result from mutations in ZIC3.

P47168	TTI2_YEAST	TEL2-interacting protein 2	19040720	Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment.

Q9UL25	RAB21_HUMAN	Ras-related protein Rab-21	17450153	Structural basis for Rab GTPase activation by VPS9 domain exchange factors.

P07271	PIF1_YEAST	DNA repair and recombination protein PIF1	16121131	The yeast Pif1p helicase removes telomerase from telomeric DNA.

P47742	GBRR2_RAT	Gamma-aminobutyric acid receptor subunit rho-2	7643126	Identification of GABAA receptor subunits in rat retina: cloning of the rat GABAA receptor rho 2-subunit cDNA.

Q10661	DPY30_CAEEL	Dosage compensation protein dpy-30	7588066	DPY-30, a nuclear protein essential early in embryogenesis for Caenorhabditis elegans dosage compensation.

Q9U9R7	SNAG_DICDI	Gamma-soluble NSF attachment protein	12175335	Syntaxin 7, syntaxin 8, Vti1 and VAMP7 (vesicle-associated membrane protein 7) form an active SNARE complex for early macropinocytic compartment fusion in Dictyostelium discoideum.

P20447	DBP3_YEAST	ATP-dependent RNA helicase DBP3	9032262	Dbp3p, a putative RNA helicase in Saccharomyces cerevisiae, is required for efficient pre-rRNA processing predominantly at site A3.

A0PJZ3	GXLT2_HUMAN	Glucoside xylosyltransferase 2	19940119	Identification of glycosyltransferase 8 family members as xylosyltransferases acting on o-glucosylated notch epidermal growth factor repeats.

P62136	PP1A_HUMAN	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit	11739654	Dynamic targeting of protein phosphatase 1 within the nuclei of living mammalian cells.

Q9UKT7	FBXL3_HUMAN	F-box/LRR-repeat protein 3	10531035	Identification of a family of human F-box proteins.

Q14191	WRN_HUMAN	Werner syndrome ATP-dependent helicase	16622405	WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing.

Q9UPN9	TRI33_HUMAN	E3 ubiquitin-protein ligase TRIM33	19135894	FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination.

Q40677	ALFC_ORYSJ	Fructose-bisphosphate aldolase, chloroplastic	8163192	Structural analysis of the chloroplastic and cytoplasmic aldolase- encoding genes implicated the occurrence of multiple loci in rice.

P33205	FXA4A_XENLA	Forkhead box protein A4-A	15656969	Of fox and frogs: fox (fork head/winged helix) transcription factors in Xenopus development.

P27986	P85A_HUMAN	Phosphatidylinositol 3-kinase regulatory subunit alpha	8276809	Direct activation of the phosphatidylinositol 3'-kinase by the insulin receptor.

P32019	I5P2_HUMAN	Type II inositol-1,4,5-trisphosphate 5-phosphatase	1718960	Cloning and expression of human 75-kDa inositol polyphosphate-5- phosphatase.

Q9SMZ4	AASS_ARATH	Alpha-aminoadipic semialdehyde synthase	11500552	A T-DNA insertion knockout of the bifunctional lysine-ketoglutarate reductase/saccharopine dehydrogenase gene elevates lysine levels in Arabidopsis seeds.

Q9QXY1	ZO3_MOUSE	Tight junction protein ZO-3	10601346	Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins.

Q9W1N5	GR59F_DROME	Putative gustatory receptor 59f	10710312	Candidate taste receptors in Drosophila.

Q9BZ71	PITM3_HUMAN	Membrane-associated phosphatidylinositol transfer protein 3	10022914	Identification of a novel family of targets of PYK2 related to Drosophila retinal degeneration B (rdgB) protein.

Q8LDQ4	TAP46_ARATH	PP2A regulatory subunit TAP46	10517853	The Arabidopsis homolog of yeast TAP42 and mammalian alpha4 binds to the catalytic subunit of protein phosphatase 2A and is induced by chilling.

Q9XYD3	HBL1_CAEEL	Hunchback-like protein	9917360	A Caenorhabditis elegans homologue of hunchback is required for late stages of development but not early embryonic patterning.

Q13472	TOP3A_HUMAN	DNA topoisomerase 3-alpha	8622991	Human TOP3: a single-copy gene encoding DNA topoisomerase III.

A2AKK5	ACNT1_MOUSE	Acyl-coenzyme A amino acid N-acyltransferase 1	17116739	A peroxisomal acyltransferase in mouse identifies a novel pathway for taurine conjugation of fatty acids.

Q92982	NINJ1_HUMAN	Ninjurin-1	9261151	Mechanism of homophilic binding mediated by ninjurin, a novel widely expressed adhesion molecule.

Q04305	UTP15_YEAST	U3 small nucleolar RNA-associated protein 15	15489292	RNA polymerase I transcription and pre-rRNA processing are linked by specific SSU processome components.

P00958	SYMC_YEAST	Methionyl-tRNA synthetase, cytoplasmic	3905796	Cytoplasmic methionyl-tRNA synthetase from Bakers' yeast. A monomer with a post-translationally modified N-terminus.

P32657	CHD1_YEAST	Chromo domain-containing protein 1	12242279	RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach.

P63345	ARC_MYCTU	Proteasome-associated ATPase	19836337	Structural insights on the Mycobacterium tuberculosis proteasomal ATPase Mpa.

Q9WTR1	TRPV2_MOUSE	Transient receptor potential cation channel subfamily V member 2	10559903	Translocation of a calcium-permeable cation channel induced by insulin-like growth factor-I.

Q15052	ARHG6_HUMAN	Rho guanine nucleotide exchange factor 6	11017088	Mutations in ARHGEF6, encoding a guanine nucleotide exchange factor for Rho GTPases, in patients with X-linked mental retardation.

Q60988	STIL_MOUSE	SCL-interrupting locus protein homolog	10385121	The SIL gene is required for mouse embryonic axial development and left-right specification.

P19934	TOLA_ECOLI	Protein tolA	2687247	Nucleotide sequences of the tolA and tolB genes and localization of their products, components of a multistep translocation system in Escherichia coli.

P46011	NRL4_ARATH	Bifunctional nitrilase/nitrile hydratase NIT4	8022831	Differential regulation of an auxin-producing nitrilase gene family in Arabidopsis thaliana.

Q9NZJ5	E2AK3_HUMAN	Eukaryotic translation initiation factor 2-alpha kinase 3	10677345	Pancreatic eukaryotic initiation factor-2alpha kinase (PEK) homologues in humans, Drosophila melanogaster and Caenorhabditis elegans that mediate translational control in response to endoplasmic reticulum stress.

Q62682	CNTN3_RAT	Contactin-3	8060619	BIG-1: a new TAG-1/F3-related member of the immunoglobulin superfamily with neurite outgrowth-promoting activity.

Q6AZ28	PIAS2_RAT	E3 SUMO-protein ligase PIAS2	9920921	A testis-specific androgen receptor coregulator that belongs to a novel family of nuclear proteins.

P09052	VASA1_DROME	ATP-dependent RNA helicase vasa, isoform A	16630817	Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa.

O14134	ELF1_SCHPO	mRNA export factor elf1	12110682	Elf1p, a member of the ABC class of ATPases, functions as a mRNA export factor in Schizosacchromyces pombe.

Q80TN5	ZDH17_MOUSE	Palmitoyltransferase ZDHHC17	15603741	Identification of PSD-95 palmitoylating enzymes.

O95750	FGF19_HUMAN	Fibroblast growth factor 19	17623664	Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21.

Q9Y3B2	EXOS1_HUMAN	3'-5' exoribonuclease CSL4 homolog	11812149	Protein-protein interactions of hCsl4p with other human exosome subunits.

P34689	GLH1_CAEEL	ATP-dependent RNA helicase glh-1	12435362	The GLH proteins, Caenorhabditis elegans P granule components, associate with CSN-5 and KGB-1, proteins necessary for fertility, and with ZYX-1, a predicted cytoskeletal protein.

Q8IYL9	PSYR_HUMAN	Psychosine receptor	9655242	Cloning, characterization, and mapping of human homolog of mouse T- cell death-associated gene.

P34260	VP33A_CAEEL	Vacuolar protein sorting-associated protein 33A	19109425	SPE-39 family proteins interact with the HOPS complex and function in lysosomal delivery.

Q63484	AKT3_RAT	RAC-gamma serine/threonine-protein kinase	7488143	Molecular cloning and characterization of a new member of the RAC protein kinase family: association of the pleckstrin homology domain of three types of RAC protein kinase with protein kinase C subspecies and beta gamma subunits of G proteins.

Q9LKZ3	RBR1_ARATH	Retinoblastoma-related protein 1	15201912	Plant retinoblastoma homologues control nuclear proliferation in the female gametophyte.

Q9UL49	TCFL5_HUMAN	Transcription factor-like 5 protein	9763657	Cloning of TCFL5 encoding a novel human basic helix-loop-helix motif protein that is specifically expressed in primary spermatocytes at the pachytene stage.

Q02795	OSTD_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit SWP1	9405463	The highly conserved Stt3 protein is a subunit of the yeast oligosaccharyltransferase and forms a subcomplex with Ost3p and Ost4p.

Q9BQ95	ECSIT_HUMAN	Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial	17344420	Cytosolic signaling protein Ecsit also localizes to mitochondria where it interacts with chaperone NDUFAF1 and functions in complex I assembly.

Q84TG3	PUB23_ARATH	E3 ubiquitin-protein ligase PUB23	18771922	Negative regulation of PAMP-triggered immunity by an E3 ubiquitin ligase triplet in Arabidopsis.

Q9Z1N4	BPNT1_RAT	3'(2'),5'-bisphosphate nucleotidase 1	11812139	Crystal structure of an enzyme displaying both inositol- polyphosphate-1-phosphatase and 3'-phosphoadenosine-5'-phosphate phosphatase activities: a novel target of lithium therapy.

P16930	FAAA_HUMAN	Fumarylacetoacetase	8364576	Characterization of the human fumarylacetoacetate hydrolase gene and identification of a missense mutation abolishing enzymatic activity.

P31646	S6A13_RAT	Sodium- and chloride-dependent GABA transporter 2	1400419	Molecular heterogeneity of the gamma-aminobutyric acid (GABA) transport system. Cloning of two novel high affinity GABA transporters from rat brain.

P40348	RFC2_YEAST	Replication factor C subunit 2	12665596	Mechanical link between cohesion establishment and DNA replication: Ctf7p/Eco1p, a cohesion establishment factor, associates with three different replication factor C complexes.

P85091	CYFP1_BOVIN	Cytoplasmic FMR1-interacting protein 1	9417078	p140Sra-1 (specifically Rac1-associated protein) is a novel specific target for Rac1 small GTPase.

P97459	NPAS1_MOUSE	Neuronal PAS domain-containing protein 1	15347806	Behavioral and regulatory abnormalities in mice deficient in the NPAS1 and NPAS3 transcription factors.

Q10099	SEH1_SCHPO	Nucleoporin seh1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q06508	VPS66_YEAST	Vacuolar protein sorting-associated protein 66	12134085	Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae.

P09661	RU2A_HUMAN	U2 small nuclear ribonucleoprotein A'	2928112	Molecular cloning of the cDNA for the human U2 snRNA-specific A' protein.

Q8BVN3	CTSR4_MOUSE	Cation channel sperm-associated protein 4	17227845	All four CatSper ion channel proteins are required for male fertility and sperm cell hyperactivated motility.

O95835	LATS1_HUMAN	Serine/threonine-protein kinase LATS1	15220930	LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1.

P47938	THIO1_DROME	Thioredoxin-1	14579129	The ThioredoxinT and deadhead gene pair encode testis- and ovary- specific thioredoxins in Drosophila melanogaster.

P05709	SIM_DROME	Protein single-minded	1760843	The Drosophila single-minded gene encodes a helix-loop-helix protein that acts as a master regulator of CNS midline development.

P41920	YRB1_YEAST	Ran-specific GTPase-activating protein 1	10825193	Yeast Ran-binding protein 1 (Yrb1) shuttles between the nucleus and cytoplasm and is exported from the nucleus via a CRM1 (XPO1)-dependent pathway.

O82804	ELF3_ARATH	Protein EARLY FLOWERING 3	11402161	ELF3 encodes a circadian clock-regulated nuclear protein that functions in an Arabidopsis PHYB signal transduction pathway.

Q9Y6C2	EMIL1_HUMAN	EMILIN-1	11278945	Isolation and characterization of EMILIN-2, a new component of the growing EMILINs family and a member of the EMI domain-containing superfamily.

Q96LT4	SAMD8_HUMAN	Sphingomyelin synthase-related protein 1	14685263	Identification of a family of animal sphingomyelin synthases.

Q04089	DOT1_YEAST	Histone-lysine N-methyltransferase, H3 lysine-79 specific	11029058	Role for the silencing protein Dot1 in meiotic checkpoint control.

D0ZRB2	SLRP_SALT1	E3 ubiquitin-protein ligase slrP	10861017	A conserved amino acid sequence directing intracellular type III secretion by Salmonella typhimurium.

O95822	DCMC_HUMAN	Malonyl-CoA decarboxylase, mitochondrial	9869665	Cloning and mutational analysis of human malonyl-coenzyme A decarboxylase.

P32806	GYP6_YEAST	GTPase-activating protein GYP6	8441469	A yeast GTPase-activating protein that interacts specifically with a member of the Ypt/Rab family.

Q68E01	INT3_HUMAN	Integrator complex subunit 3	19605351	hSSB1 and hSSB2 form similar multiprotein complexes that participate in DNA damage response.

Q12184	ADRX_YEAST	Adrenodoxin homolog, mitochondrial	10655482	A mitochondrial ferredoxin is essential for biogenesis of cellular iron-sulfur proteins.

Q9LPW3	SCRM2_ARATH	Transcription factor SCREAM2	18641265	SCREAM/ICE1 and SCREAM2 specify three cell-state transitional steps leading to arabidopsis stomatal differentiation.

O94446	ESA1_SCHPO	Histone acetyltransferase mst1	16199868	Schizosaccharomyces pombe mst2+ encodes a MYST family histone acetyltransferase that negatively regulates telomere silencing.

Q86YS3	RFIP4_HUMAN	Rab11 family-interacting protein 4	15601896	The FIP3-Rab11 protein complex regulates recycling endosome targeting to the cleavage furrow during late cytokinesis.

O48946	CESA1_ARATH	Cellulose synthase A catalytic subunit 1 [UDP-forming]	12068120	Functional analysis of the cellulose synthase genes CesA1, CesA2, and CesA3 in Arabidopsis.

P50613	CDK7_HUMAN	Cell division protein kinase 7	8208544	Two novel human serine/threonine kinases with homologies to the cell cycle regulating Xenopus MO15, and NIMA kinases: cloning and characterization of their expression pattern.

O65312	MEDEA_ARATH	Histone-lysine N-methyltransferase MEDEA	11148284	Mutations in the FIE and MEA genes that encode interacting polycomb proteins cause parent-of-origin effects on seed development by distinct mechanisms.

Q9FLT2	IPMKB_ARATH	Inositol polyphosphate multikinase beta	12226109	Molecular and biochemical characterization of two plant inositol polyphosphate 6-/3-/5-kinases.

Q8IR79	LIMK1_DROME	LIM domain kinase 1	14972681	Rho-LIM kinase signaling regulates ecdysone-induced gene expression and morphogenesis during Drosophila metamorphosis.

P41411	CDC18_SCHPO	Cell division control protein 18	8521469	p65cdc18 plays a major role controlling the initiation of DNA replication in fission yeast.

Q9C8G9	AB1C_ARATH	ABC transporter C family member 1	15133126	Arabidopsis immunophilin-like TWD1 functionally interacts with vacuolar ABC transporters.

P0A9K9	SLYD_ECOLI	FKBP-type peptidyl-prolyl cis-trans isomerase slyD	16388577	SlyD proteins from different species exhibit high prolyl isomerase and chaperone activities.

Q01995	TAGL_HUMAN	Transgelin	9615232	Expression and cytogenetic localization of the human SM22 gene (TAGLN).

P21691	SIR1_YEAST	Regulatory protein SIR1	8622770	Role of interactions between the origin recognition complex and SIR1 in transcriptional silencing.

Q672J9	NOX3_MOUSE	NADPH oxidase 3	15326186	NOX3, a superoxide-generating NADPH oxidase of the inner ear.

O54918	B2L11_MOUSE	Bcl-2-like protein 11	14499110	The structure of a Bcl-xL/Bim fragment complex: implications for Bim function.

P60165	KA112_PARVI	Potassium channel toxin alpha-KTx 11.2	14561751	A subfamily of acidic alpha-K(+) toxins.

Q9SEV0	BAN_ARATH	Anthocyanidin reductase	12532018	Role of anthocyanidin reductase, encoded by BANYULS in plant flavonoid biosynthesis.

P83369	LSM11_HUMAN	U7 snRNA-associated Sm-like protein LSm11	12975319	Unique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processing.

Q02767	VPS28_YEAST	Vacuolar protein sorting-associated protein 28	16615894	Structural and functional organization of the ESCRT-I trafficking complex.

O43542	XRCC3_HUMAN	DNA repair protein XRCC3	9660962	XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages.

P40339	RFC4_YEAST	Replication factor C subunit 4	12912927	Elg1 forms an alternative RFC complex important for DNA replication and genome integrity.

Q9BXP5	SRRT_HUMAN	Serrate RNA effector molecule homolog	11239002	Comparative analysis of the gene-dense ACHE/TFR2 region on human chromosome 7q22 with the orthologous region on mouse chromosome 5.

O19010	CRIS3_HORSE	Cysteine-rich secretory protein 3	9748582	Equine CRISP-3: primary structure and expression in the male genital tract.

Q9PTJ3	RBTN2_DANRE	Rhombotin-2	14602685	Lmo2 and Scl/Tal1 convert non-axial mesoderm into haemangioblasts which differentiate into endothelial cells in the absence of Gata1.

P37303	GLY1_YEAST	Low specificity L-threonine aldolase	9163906	Identification of Saccharomyces cerevisiae GLY1 as a threonine aldolase: a key enzyme in glycine biosynthesis.

P11491	PPB_YEAST	Repressible alkaline phosphatase	2676517	Membrane protein sorting: biosynthesis, transport and processing of yeast vacuolar alkaline phosphatase.

Q9LQN6	P2C04_ARATH	Probable protein phosphatase 2C 4	16112663	POL and related phosphatases are dosage-sensitive regulators of meristem and organ development in Arabidopsis.

Q03220	CTL1_YEAST	Polynucleotide 5'-triphosphatase	10219091	A Saccharomyces cerevisiae RNA 5'-triphosphatase related to mRNA capping enzyme.

Q01593	ABI3_ARATH	B3 domain-containing transcription factor ABI3	10743655	Interactions of the developmental regulator ABI3 with proteins identified from developing Arabidopsis seeds.

P52756	RBM5_HUMAN	RNA-binding protein 5	18840686	Up-regulation of the proapoptotic caspase 2 splicing isoform by a candidate tumor suppressor, RBM5.

P41543	OST1_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1	15831493	Subunits of the translocon interact with components of the oligosaccharyl transferase complex.

P36039	EMC3_YEAST	ER membrane protein complex subunit 3	19325107	Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum.

P58907	LECA_DIOVI	Lectin alpha chain	10082964	Molecular characterization and crystallization of Diocleinae lectins.

O14980	XPO1_HUMAN	Exportin-1	9837918	The specificity of the CRM1-Rev nuclear export signal interaction is mediated by RanGTP.

O74825	RPB4_SCHPO	DNA-directed RNA polymerase II subunit rpb4	10523639	The Rpb4 subunit of fission yeast Schizosaccharomyces pombe RNA polymerase II is essential for cell viability and similar in structure to the corresponding subunits of higher eukaryotes.

Q9C0V7	YHJ2_SCHPO	Uncharacterized sulfatase PB10D8.02c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O43182	RHG06_HUMAN	Rho GTPase-activating protein 6	9417914	Cloning and characterization of a novel rho-type GTPase-activating protein gene (ARHGAP6) from the critical region for microphthalmia with linear skin defects.

Q9LSQ2	PP239_ARATH	Putative pentatricopeptide repeat-containing protein At3g16890, mitochondrial	18305213	Arabidopsis PPR40 connects abiotic stress responses to mitochondrial electron transport.

O61705	SCXA_MESMA	Neurotoxin BmK-M10	15200476	Purification and characterization of a new peptide with analgesic effect from the scorpion Buthus martensi Karch.

Q9WUV6	CAZA3_RAT	F-actin-capping protein subunit alpha-3	9406198	Expression of a testis-specific putative actin-capping protein associated with the developing acrosome during rat spermiogenesis.

Q9HAN9	NMNA1_HUMAN	Nicotinamide mononucleotide adenylyltransferase 1	16118205	Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms.

Q92398	SPM1_SCHPO	Mitogen-activated protein kinase spm1	9135147	Spm1, a stress-activated MAP kinase that regulates morphogenesis in S.pombe.

Q8WU17	RN139_HUMAN	E3 ubiquitin-protein ligase RNF139	9689122	The hereditary renal cell carcinoma 3;8 translocation fuses FHIT to a patched-related gene, TRC8.

P32588	PUB1_YEAST	Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1	8413212	PUB1 is a major nuclear and cytoplasmic polyadenylated RNA-binding protein in Saccharomyces cerevisiae.

P0AE18	AMPM_ECOLI	Methionine aminopeptidase	3027045	Processing of the initiation methionine from proteins: properties of the Escherichia coli methionine aminopeptidase and its gene structure.

P53550	DCP2_YEAST	mRNA-decapping enzyme subunit 2	11139489	Two related proteins, Edc1p and Edc2p, stimulate mRNA decapping in Saccharomyces cerevisiae.

P55884	EIF3B_HUMAN	Eukaryotic translation initiation factor 3 subunit B	17581632	Reconstitution reveals the functional core of mammalian eIF3.

Q14978	NOLC1_HUMAN	Nucleolar and coiled-body phosphoprotein 1	7657714	Cell-cycle-dependent alterations of a highly phosphorylated nucleolar protein p130 are associated with nucleologenesis.

P50530	SCK1_SCHPO	Serine/threonine-protein kinase sck1	9245826	Protein kinase Sck1 is involved in trehalase activation by glucose and nitrogen source in the fission yeast Schizosaccharomyces pombe.

P07357	CO8A_HUMAN	Complement component C8 alpha chain	2820471	Complementary DNA and derived amino acid sequence of the alpha subunit of human complement protein C8: evidence for the existence of a separate alpha subunit messenger RNA.

P55769	NH2L1_HUMAN	NHP2-like protein 1	8978773	Cloning and mapping of a human novel cDNA (NHP2L1) that encodes a protein highly homologous to yeast nuclear protein NHP2.

Q9UN37	VPS4A_HUMAN	Vacuolar protein sorting-associated protein 4A	17928862	ESCRT-III recognition by VPS4 ATPases.

P28817	HIBCH_YEAST	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

P49450	CENPA_HUMAN	Histone H3-like centromeric protein A	19410545	HJURP is a cell-cycle-dependent maintenance and deposition factor of CENP-A at centromeres.

Q93034	CUL5_HUMAN	Cullin-5	9037604	Identification and analysis of expression of human VACM-1, a cullin gene family member located on chromosome 11q22-23.

Q14761	PTCA_HUMAN	Protein tyrosine phosphatase receptor type C-associated protein	7961877	LPAP, a novel 32-kDa phosphoprotein that interacts with CD45 in human lymphocytes.

O04130	SERA_ARATH	D-3-phosphoglycerate dehydrogenase, chloroplastic	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

P0A6L4	NANA_ECOLI	N-acetylneuraminate lyase	1646603	Purification, crystallization and characterization of N- acetylneuraminate lyase from Escherichia coli.

Q2QGD7	ZXDC_HUMAN	Zinc finger protein ZXDC	17493635	The zinc finger proteins ZXDA and ZXDC form a complex that binds CIITA and regulates MHC II gene transcription.

Q3MKQ2	BEX1_RAT	Protein BEX1	16498402	Bex1, a novel interactor of the p75 neurotrophin receptor, links neurotrophin signaling to the cell cycle.

Q10099	SEH1_SCHPO	Nucleoporin seh1	15116432	Identification of genes encoding putative nucleoporins and transport factors in the fission yeast Schizosaccharomyces pombe: a deletion analysis.

Q8K3W0	BRE_MOUSE	BRCA1-A complex subunit BRE	9737713	BRE: a modulator of TNF-alpha action.

P80370	DLK1_HUMAN	Protein delta homolog 1	8095043	dlk, a putative mammalian homeotic gene differentially expressed in small cell lung carcinoma and neuroendocrine tumor cell line.

P04208	LV106_HUMAN	Ig lambda chain V-I region WAH	6407018	Complete covalent structure of a human immunoglobulin D: sequence of the lambda light chain.

P92204	NELFE_DROME	Negative elongation factor E	12782658	NELF and DSIF cause promoter proximal pausing on the hsp70 promoter in Drosophila.

P53564	CUX1_MOUSE	Homeobox protein cut-like 1	11544187	The transcriptional repressor CDP (Cutl1) is essential for epithelial cell differentiation of the lung and the hair follicle.

Q9UBE0	SAE1_HUMAN	SUMO-activating enzyme subunit 1	9920803	In vitro SUMO-1 modification requires two enzymatic steps, E1 and E2.

P40955	CHS6_YEAST	Chitin biosynthesis protein CHS6	17000877	Exomer: a coat complex for transport of select membrane proteins from the trans-Golgi network to the plasma membrane in yeast.

P53195	COG7_YEAST	Conserved oligomeric Golgi complex subunit 7	11703943	The Sec34/35 Golgi transport complex is related to the exocyst, defining a family of complexes involved in multiple steps of membrane traffic.

Q24423	NOC_DROME	Zinc finger protein Noc	8289824	The Drosophila l(2)35Ba/nocA gene encodes a putative Zn finger protein involved in the development of the embryonic brain and the adult ocellar structures.

P41911	GPD2_YEAST	Glycerol-3-phosphate dehydrogenase [NAD+] 2, mitochondrial	9171333	The two isoenzymes for yeast NAD+-dependent glycerol 3-phosphate dehydrogenase encoded by GPD1 and GPD2 have distinct roles in osmoadaptation and redox regulation.

P39923	NPR2_YEAST	Nitrogen permease regulator 2	19521502	A genome-wide screen for regulators of TORC1 in response to amino acid starvation reveals a conserved Npr2/3 complex.

Q8RYC8	ARFS_ARATH	Auxin response factor 19	9342315	Protein-protein interactions among the Aux/IAA proteins.

Q9FLP0	MA651_ARATH	65-kDa microtubule-associated protein 1	20215588	Arabidopsis homologs of nucleus- and phragmoplast-localized kinase 2 and 3 and mitogen-activated protein kinase 4 are essential for microtubule organization.

Q9UTH0	NU132_SCHPO	Nucleoporin nup132	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

P0AE60	CEDA_ECOLI	Cell division activator CedA	9427399	CedA is a novel Escherichia coli protein that activates the cell division inhibited by chromosomal DNA over-replication.

Q9R1P4	PSA1_MOUSE	Proteasome subunit alpha type-1	19526544	Proteomics of RAW 264.7 macrophages upon interaction with heat- inactivated Candida albicans cells unravel an anti-inflammatory response.

Q12948	FOXC1_HUMAN	Forkhead box protein C1	9792859	Mutations of the forkhead/winged-helix gene, FKHL7, in patients with Axenfeld-Rieger anomaly.

P15424	MS116_YEAST	ATP-dependent RNA helicase MSS116, mitochondrial	15618406	The splicing of yeast mitochondrial group I and group II introns requires a DEAD-box protein with RNA chaperone function.

Q60994	ADIPO_MOUSE	Adiponectin	11479627	The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity.

P41047	TNFL6_MOUSE	Tumor necrosis factor ligand superfamily member 6	7511063	Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand.

P35567	CDK1A_XENLA	Cell division protein kinase 1-A	15611625	Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins.

Q92985	IRF7_HUMAN	Interferon regulatory factor 7	9786932	Characterization of the interferon regulatory factor-7 and its potential role in the transcription activation of interferon A genes.

Q07283	TRHY_HUMAN	Trichohyalin	7686953	Trichohyalin: a structural protein of hair, tongue, nail, and epidermis.

P38226	CST26_YEAST	Uncharacterized acyltransferase CST26	14562095	Global analysis of protein localization in budding yeast.

Q03526	ITK_MOUSE	Tyrosine-protein kinase ITK/TSK	19597499	Themis controls thymocyte selection through regulation of T cell antigen receptor-mediated signaling.

Q99683	M3K5_HUMAN	Mitogen-activated protein kinase kinase kinase 5	9743501	Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx.

Q93074	MED12_HUMAN	Mediator of RNA polymerase II transcription subunit 12	17000779	Mediator modulates Gli3-dependent Sonic hedgehog signaling.

O74311	NAA30_SCHPO	N-alpha-acetyltransferase 30, NatC catalytic subunit	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q03433	VPS71_YEAST	Vacuolar protein sorting-associated protein 71	14690608	A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1.

P25714	OXAA_ECOLI	Inner membrane protein oxaA	10949305	YidC mediates membrane protein insertion in bacteria.

Q06142	IMB1_YEAST	Importin subunit beta-1	7622450	Identification of a yeast karyopherin heterodimer that targets import substrate to mammalian nuclear pore complexes.

Q9I7K5	TMEDE_DROME	Transmembrane emp24 domain-containing protein eca	15327786	Drosophila p24 homologues eclair and baiser are necessary for the activity of the maternally expressed Tkv receptor during early embryogenesis.

P47125	I23O_YEAST	Indoleamine 2,3-dioxygenase family protein	12062417	Aerobic and anaerobic NAD+ metabolism in Saccharomyces cerevisiae.

Q8TAQ2	SMRC2_HUMAN	SWI/SNF complex subunit SMARCC2	10078207	Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits.

Q9NR19	ACSA_HUMAN	Acetyl-coenzyme A synthetase, cytoplasmic	10843999	Molecular characterization of human acetyl-CoA synthetase, an enzyme regulated by sterol regulatory element-binding proteins.

P20115	CISY4_ARATH	Citrate synthase 4, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q9Y4I5	MTL5_HUMAN	Tesmin	10191092	A novel testis-specific metallothionein-like protein, tesmin, is an early marker of male germ cell differentiation.

Q9W741	NOGG1_DANRE	Noggin-1	10491267	Three different noggin genes antagonize the activity of bone morphogenetic proteins in the zebrafish embryo.

Q8N0Y7	PGAM4_HUMAN	Probable phosphoglycerate mutase 4	11961099	Evolution of the phosphoglycerate mutase processed gene in human and chimpanzee revealing the origin of a new primate gene.

Q9Y618	NCOR2_HUMAN	Nuclear receptor corepressor 2	10097068	SMRTe, a silencing mediator for retinoid and thyroid hormone receptors-extended isoform that is more related to the nuclear receptor corepressor.

Q96EK5	KBP_HUMAN	KIF1-binding protein	16225668	The novel protein KBP regulates mitochondria localization by interaction with a kinesin-like protein.

Q9Y3D3	RT16_HUMAN	28S ribosomal protein S16, mitochondrial	11279123	The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present.

Q09614	PTC1_CAEEL	Protein patched homolog 1	10921907	A C. elegans patched gene, ptc-1, functions in germ-line cytokinesis.

P22216	RAD53_YEAST	Serine/threonine-protein kinase RAD53	15024067	Mdt1, a novel Rad53 FHA1 domain-interacting protein, modulates DNA damage tolerance and G(2)/M cell cycle progression in Saccharomyces cerevisiae.

P84118	BURS_PERAM	Bursicon	12271490	Cellular localization of bursicon using antisera against partial peptide sequences of this insect cuticle-sclerotizing neurohormone.

Q9S7M2	TI10B_ARATH	Protein TIFY 10B	20360743	NINJA connects the co-repressor TOPLESS to jasmonate signalling.

Q9P375	YLM6_SCHPO	Uncharacterized rhomboid protein C19B12.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q18825	BAR1_CAEEL	Beta-catenin/armadillo-related protein 1	15282167	Identification of evolutionarily conserved promoter elements and amino acids required for function of the C. elegans beta-catenin homolog BAR-1.

P11531	DMD_MOUSE	Dystrophin	9214383	Differential association of syntrophin pairs with the dystrophin complex.

P87027	SPG1_SCHPO	Septum-promoting GTP-binding protein 1	15062098	Sid4p-Cdc11p assembles the septation initiation network and its regulators at the S. pombe SPB.

Q9WTL8	BMAL1_MOUSE	Aryl hydrocarbon receptor nuclear translocator-like protein 1	12897057	BMAL1-dependent circadian oscillation of nuclear CLOCK: posttranslational events induced by dimerization of transcriptional activators of the mammalian clock system.

Q99247	YO087_YEAST	Uncharacterized WD repeat-containing protein YOL087C	14562095	Global analysis of protein localization in budding yeast.

Q9P7M4	YIOE_SCHPO	Uncharacterized protein P27G11.14c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P36528	RM17_YEAST	54S ribosomal protein L17, mitochondrial	9151978	Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae.

Q965H3	SOP2_CAEEL	Polycomb protein sop-2	15107848	SUMO modification is required for in vivo Hox gene regulation by the Caenorhabditis elegans Polycomb group protein SOP-2.

Q27268	UAP56_DROME	ATP-dependent RNA helicase WM6	9215899	A new enhancer of position-effect variegation in Drosophila melanogaster encodes a putative RNA helicase that binds chromosomes and is regulated by the cell cycle.

Q99584	S10AD_HUMAN	Protein S100-A13	17374362	Crystal structure study on human S100A13 at 2.0 A resolution.

P38827	SET1_YEAST	Histone-lysine N-methyltransferase, H3 lysine-4 specific	11742990	The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4.

Q84WU8	FTSH3_ARATH	ATP-dependent zinc metalloprotease FTSH 3, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P25615	DPO4_YEAST	DNA polymerase IV	12235149	A physical and functional interaction between yeast Pol4 and Dnl4- Lif1 links DNA synthesis and ligation in nonhomologous end joining.

O60759	CYTIP_HUMAN	Cytohesin-interacting protein	11867758	Cybr, a cytokine-inducible protein that binds cytohesin-1 and regulates its activity.

Q9SQH9	AMT13_ARATH	Ammonium transporter 1 member 3	17026539	Additive contribution of AMT1;1 and AMT1;3 to high-affinity ammonium uptake across the plasma membrane of nitrogen-deficient Arabidopsis roots.

Q9P7W4	POF10_SCHPO	F-box/WD repeat-containing protein pof10	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q99500	S1PR3_HUMAN	Sphingosine 1-phosphate receptor 3	9409733	Identification of cDNAs encoding two G protein-coupled receptors for lysosphingolipids.

Q8VYE5	E1312_ARATH	Glucan endo-1,3-beta-glucosidase 12	14517339	Proteomic analysis of glycosylphosphatidylinositol-anchored membrane proteins.

Q92889	XPF_HUMAN	DNA repair endonuclease XPF	19596236	Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases.

Q9Y4K3	TRAF6_HUMAN	TNF receptor-associated factor 6	16221674	FLN29, a novel interferon- and LPS-inducible gene acting as a negative regulator of toll-like receptor signaling.

Q8WYP3	RIN2_HUMAN	Ras and Rab interactor 2	1849280	Expression of three mammalian cDNAs that interfere with RAS function in Saccharomyces cerevisiae.

Q9FXH5	PUP14_ARATH	Probable purine permease 14	10662864	A new family of high-affinity transporters for adenine, cytosine, and purine derivatives in Arabidopsis.

P97817	CDR2_MOUSE	Cerebellar degeneration-related protein 2	9006982	A post-transcriptional regulatory mechanism restricts expression of the paraneoplastic cerebellar degeneration antigen cdr2 to immune privileged tissues.

P13587	ATN1_YEAST	Sodium transport ATPase 1	9315618	Overexpression of the sodium ATPase of Saccharomyces cerevisiae: conditions for phosphorylation from ATP and Pi.

Q15063	POSTN_HUMAN	Periostin	8363580	Osteoblast-specific factor 2: cloning of a putative bone adhesion protein with homology with the insect protein fasciclin I.

O00560	SDCB1_HUMAN	Syntenin-1	9391086	Syntenin, a PDZ protein that binds syndecan cytoplasmic domains.

Q8CJB9	BRE1B_RAT	E3 ubiquitin-protein ligase BRE1B	12121982	Staring, a novel E3 ubiquitin-protein ligase that targets syntaxin 1 for degradation.

Q06134	SPO77_YEAST	Sporulation-specific protein 77	15590821	Morphogenetic pathway of spore wall assembly in Saccharomyces cerevisiae.

O74740	CFT2_SCHPO	Cleavage factor two protein 2	14617822	A comparative analysis of an orthologous proteomic environment in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe.

Q9QZT0	CUZD1_RAT	CUB and zona pellucida-like domain-containing protein 1	10542259	Cloning and uterus/oviduct-specific expression of a novel estrogen- regulated gene (ERG1).

P14317	HCLS1_HUMAN	Hematopoietic lineage cell-specific protein	2587259	Isolation and characterization of a novel human gene expressed specifically in the cells of hematopoietic lineage.

O49279	SKI15_ARATH	SKP1-interacting partner 15	12169662	The F-box subunit of the SCF E3 complex is encoded by a diverse superfamily of genes in Arabidopsis.

Q86WV6	TM173_HUMAN	Transmembrane protein 173	18724357	STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling.

P50085	PHB2_YEAST	Prohibitin-2	12237468	A structure for the yeast prohibitin complex: structure prediction and evidence from chemical crosslinking and mass spectrometry.

O14763	TR10B_HUMAN	Tumor necrosis factor receptor superfamily member 10B	9373179	Characterization of two receptors for TRAIL.

Q6RYS9	DOPR3_CAEEL	Dopamine receptor 3	16001968	Characterization of a novel D2-like dopamine receptor with a truncated splice variant and a D1-like dopamine receptor unique to invertebrates from Caenorhabditis elegans.

O74288	ABFB_EMENI	Alpha-N-arabinofuranosidase B	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

P28340	DPOD1_HUMAN	DNA polymerase delta catalytic subunit	15670210	Human Werner helicase interacting protein 1 (WRNIP1) functions as a novel modulator for DNA polymerase delta.

Q6TEK4	VKOR1_RAT	Vitamin K epoxide reductase complex subunit 1	14765194	Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2.

Q03164	MLL1_HUMAN	Histone-lysine N-methyltransferase MLL	16990798	Solution structure of the nonmethyl-CpG-binding CXXC domain of the leukaemia-associated MLL histone methyltransferase.

P11142	HSP7C_HUMAN	Heat shock cognate 71 kDa protein	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

Q03661	ESC1_YEAST	Silent chromatin protein ESC1	12417731	Esc1, a nuclear periphery protein required for Sir4-based plasmid anchoring and partitioning.

Q08176	MIM1_YEAST	Mitochondrial import protein 1	15608614	Mim1, a protein required for the assembly of the TOM complex of mitochondria.

P78356	PI42B_HUMAN	Phosphatidylinositol-5-phosphate 4-kinase type-2 beta	9038203	A novel interaction between the juxtamembrane region of the p55 tumor necrosis factor receptor and phosphatidylinositol-4-phosphate 5- kinase.

O75830	SPI2_HUMAN	Serpin I2	10097100	Suppression of breast cancer growth and metastasis by a serpin myoepithelium-derived serine proteinase inhibitor expressed in the mammary myoepithelial cells.

P21675	TAF1_HUMAN	Transcription initiation factor TFIID subunit 1	15960975	Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

Q9Y2R2	PTN22_HUMAN	Tyrosine-protein phosphatase non-receptor type 22	18056643	Structure, inhibitor, and regulatory mechanism of Lyp, a lymphoid- specific tyrosine phosphatase implicated in autoimmune diseases.

Q9TTY5	PTAFR_BOVIN	Platelet-activating factor receptor	11438398	Fluorometric detection of platelet activating factor receptor in cultured oviductal epithelial and stromal cells and endometrial stromal cells from bovine at different stages of the oestrous cycle and early pregnancy.

P62491	RB11A_HUMAN	Ras-related protein Rab-11A	15601896	The FIP3-Rab11 protein complex regulates recycling endosome targeting to the cleavage furrow during late cytokinesis.

O88444	ADCY1_MOUSE	Adenylate cyclase type 1	9662407	Loss of adenylyl cyclase I activity disrupts patterning of mouse somatosensory cortex.

P48524	BUL1_YEAST	Ubiquitin ligase-binding protein BUL1	9931424	The PY-motif of Bul1 protein is essential for growth of Saccharomyces cerevisiae under various stress conditions.

Q9NQ94	A1CF_HUMAN	APOBEC1 complementation factor	12881431	The apolipoprotein B mRNA editing complex performs a multifunctional cycle and suppresses nonsense-mediated decay.

O13871	YE16_SCHPO	Uncharacterized methyltransferase C1B3.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P48594	SPB4_HUMAN	Serpin B4	7589435	Identification of a novel human serpin gene; cloning sequencing and expression of leupin.

P58905	AMT11_SOLLC	Ammonium transporter 1 member 1	8755617	Preferential expression of an ammonium transporter and of two putative nitrate transporters in root hairs of tomato.

Q93038	TNR25_HUMAN	Tumor necrosis factor receptor superfamily member 25	9114039	LARD: a new lymphoid-specific death domain containing receptor regulated by alternative pre-mRNA splicing.

P48445	BPL1_YEAST	Biotin--protein ligase	14562095	Global analysis of protein localization in budding yeast.

P43681	ACHA4_HUMAN	Neuronal acetylcholine receptor subunit alpha-4	7550350	A missense mutation in the neuronal nicotinic acetylcholine receptor alpha-4 subunit is associated with autosomal dominant nocturnal frontal lobe epilepsy.

P09556	PYR5_DICDI	Uridine 5'-monophosphate synthase	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P32898	CYM1_YEAST	Mitochondrial presequence protease	15772085	Role of the novel metallopeptidase Mop112 and saccharolysin for the complete degradation of proteins residing in different subcompartments of mitochondria.

A0QZ49	DOP_MYCS2	Pup deamidase/depupylase	20025664	Deletion of dop in Mycobacterium smegmatis abolishes pupylation of protein substrates in vivo.

Q63357	MYO1D_RAT	Myosin-Id	8034741	Rat myr4 defines a novel subclass of myosin I: identification, distribution, localization, and mapping of calmodulin-binding sites with differential calcium sensitivity.

Q12287	COX17_YEAST	Cytochrome c oxidase copper chaperone	9407107	Purification, characterization, and localization of yeast Cox17p, a mitochondrial copper shuttle.

Q9U8W8	TL5A_TACTR	Techylectin-5A	10468566	Horseshoe crab acetyl group-recognizing lectins involved in innate immunity are structurally related to fibrinogen.

Q9VVR6	SGF11_DROME	SAGA-associated factor 11 homolog	18206972	A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing.

Q60662	AKAP4_MOUSE	A-kinase anchor protein 4	9852104	Identification of tethering domains for protein kinase A type Ialpha regulatory subunits on sperm fibrous sheath protein FSC1.

Q9WU34	SEPT3_RAT	Neuronal-specific septin-3	10744683	Phosphorylation of a new brain-specific septin, G-septin, by cGMP- dependent protein kinase.

P17558	RTPT_YEAST	37S ribosomal protein PET123, mitochondrial	11278769	Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues.

O14791	APOL1_HUMAN	Apolipoprotein L1	9325276	Apolipoprotein L, a new human high density lipoprotein apolipoprotein expressed by the pancreas. Identification, cloning, characterization, and plasma distribution of apolipoprotein L.

Q6AWU6	HOL3_ARATH	Probable thiol methyltransferase 2	19419967	Arabidopsis HARMLESS TO OZONE LAYER protein methylates a glucosinolate breakdown product and functions in resistance to Pseudomonas syringae pv. maculicola.

Q15378	RBY1H_HUMAN	Putative RNA-binding motif protein, Y chromosome, family 1 member H	9598316	Structure and organization of the RBMY genes on the human Y chromosome: transposition and amplification of an ancestral autosomal hnRNPG gene.

Q09739	MCP7_SCHPO	Meiotic coiled-coil protein 7	15210864	Mcp7, a meiosis-specific coiled-coil protein of fission yeast, associates with Meu13 and is required for meiotic recombination.

Q95UN8	M3KSL_DROME	Mitogen-activated protein kinase kinase kinase	12504027	Activation of the Drosophila MLK by ceramide reveals TNF-alpha and ceramide as agonists of mammalian MLK3.

P53276	UTP8_YEAST	U3 small nucleolar RNA-associated protein 8	12068309	A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis.

Q9LE82	RAGP1_ARATH	RAN GTPase-activating protein 1	18591351	Two distinct interacting classes of nuclear envelope-associated coiled-coil proteins are required for the tissue-specific nuclear envelope targeting of Arabidopsis RanGAP.

O43272	PROD_HUMAN	Proline dehydrogenase, mitochondrial	10192398	The gene encoding proline dehydrogenase modulates sensorimotor gating in mice.

Q9H6T0	ESRP2_HUMAN	Epithelial splicing regulatory protein 2	19285943	ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing.

Q08499	PDE4D_HUMAN	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	10913353	Phosphodiesterases 4D and 7A splice variants in the response of HUVEC cells to TNF-alpha1.

Q12774	ARHG5_HUMAN	Rho guanine nucleotide exchange factor 5	8134109	Expression cDNA cloning of a novel oncogene with sequence similarity to regulators of small GTP-binding proteins.

P53834	HCH1_YEAST	Hsp90 co-chaperone HCH1	12504007	Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1.

P40454	PTPA1_YEAST	Serine/threonine-protein phosphatase 2A activator 1	16380387	The protein phosphatase 2A phosphatase activator is a novel peptidyl- prolyl cis/trans-isomerase.

P70627	FOLH1_RAT	Glutamate carboxypeptidase 2	9501243	Isolation and expression of a rat brain cDNA encoding glutamate carboxypeptidase II.

P40185	MMF1_YEAST	Protein MMF1, mitochondrial	11003673	Mmf1p, a novel yeast mitochondrial protein conserved throughout evolution and involved in maintenance of the mitochondrial genome.

Q8WWY3	PRP31_HUMAN	U4/U6 small nuclear ribonucleoprotein Prp31	17412961	Binding of the human Prp31 Nop domain to a composite RNA-protein platform in U4 snRNP.

P53258	GYP2_YEAST	GTPase-activating protein GYP2	12807768	Opposite roles of the F-box protein Rcy1p and the GTPase-activating protein Gyp2p during recycling of internalized proteins in yeast.

Q8CJ11	GPR64_RAT	G-protein coupled receptor 64	12420295	HE6, a two-subunit heptahelical receptor associated with apical membranes of efferent and epididymal duct epithelia.

P36954	RPB9_HUMAN	DNA-directed RNA polymerase II subunit RPB9	8265347	Structure of the gene encoding the 14.5 kDa subunit of human RNA polymerase II.

Q6ZMT4	KDM7_HUMAN	Lysine-specific demethylase 7	20023638	Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.

Q9V730	EXT1_DROME	Exostosin-1	14998928	Distinct and collaborative roles of Drosophila EXT family proteins in morphogen signalling and gradient formation.

Q54RV9	SGPL_DICDI	Sphingosine-1-phosphate lyase	10974109	Molecular basis for resistance to the anticancer drug cisplatin in Dictyostelium.

Q9FLP0	MA651_ARATH	65-kDa microtubule-associated protein 1	15908607	Two microtubule-associated proteins of the Arabidopsis MAP65 family function differently on microtubules.

Q9EPQ1	TLR1_MOUSE	Toll-like receptor 1	11095740	The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between Toll-like receptors.

Q07977	SIA8B_RAT	Alpha-2,8-sialyltransferase 8B	7685014	Polymerase chain reaction cloning of a developmentally regulated member of the sialyltransferase gene family.

Q91ZR5	CTSR1_MOUSE	Cation channel sperm-associated protein 1	17478420	CatSperbeta, a novel transmembrane protein in the CatSper channel complex.

P01556	CHTB_VIBCH	Cholera enterotoxin subunit B	6646234	Cholera toxin genes: nucleotide sequence, deletion analysis and vaccine development.

Q9SJI8	MBF1A_ARATH	Multiprotein-bridging factor 1a	14988493	Three Arabidopsis MBF1 homologs with distinct expression profiles play roles as transcriptional co-activators.

P98160	PGBM_HUMAN	Basement membrane-specific heparan sulfate proteoglycan core protein	11956183	The type XIII collagen ectodomain is a 150-nm rod and capable of binding to fibronectin, nidogen-2, perlecan, and heparin.

Q9QUS4	HEY2_MOUSE	Hairy/enhancer-of-split related with YRPW motif protein 2	11095750	Members of the HRT family of basic helix-loop-helix proteins act as transcriptional repressors downstream of Notch signaling.

P12883	MYH7_HUMAN	Myosin-7	3021460	Partial characterization of the human beta-myosin heavy-chain gene which is expressed in heart and skeletal muscle.

P42704	LPPRC_HUMAN	Leucine-rich PPR motif-containing protein, mitochondrial	17050673	Defects in energy homeostasis in Leigh syndrome French Canadian variant through PGC-1alpha/LRP130 complex.

O43043	SCAP_SCHPO	Sterol regulatory element-binding protein cleavage-activating protein	15797383	SREBP pathway responds to sterols and functions as an oxygen sensor in fission yeast.

Q60928	GGT1_MOUSE	Gamma-glutamyltranspeptidase 1	8566783	Cloning of cDNA and genomic structure of the mouse gamma-glutamyl transpeptidase-encoding gene.

Q14CN2	CLCA4_HUMAN	Calcium-activated chloride channel regulator 4	10437792	Identification of three novel members of the calcium-dependent chloride channel (CaCC) family predominantly expressed in the digestive tract and trachea.

P46678	TFC5_YEAST	Transcription factor TFIIIB component B''	7568218	Cloning, expression, and function of TFC5, the gene encoding the B' component of the Saccharomyces cerevisiae RNA polymerase III transcription factor TFIIIB.

Q04751	NAT4_YEAST	Histone-specific N-acetyltransferase NAT4	12915400	An Nalpha-acetyltransferase responsible for acetylation of the N- terminal residues of histones H4 and H2A.

Q9UTQ7	ARP9_SCHPO	SWI/SNF and RSC complexes subunit arp9	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9H2A2	AL8A1_HUMAN	Aldehyde dehydrogenase family 8 member A1	11007799	cDNA cloning and expression of a human aldehyde dehydrogenase (ALDH) active with 9-cis-retinal and identification of a rat ortholog, ALDH12.

P0C188	PNTB_RHORU	NAD(P) transhydrogenase subunit beta	7844118	Energy-transducing nicotinamide nucleotide transhydrogenase: nucleotide sequences of the genes and predicted amino acid sequences of the subunits of the enzyme from Rhodospirillum rubrum.

Q800Q5	T7L1B_DANRE	Transcription factor 7-like 1-B	15659486	Wnt1 regulates neurogenesis and mediates lateral inhibition of boundary cell specification in the zebrafish hindbrain.

P47147	YMR1_YEAST	Phosphoinositide 3-phosphatase	15169871	Essential role for the myotubularin-related phosphatase Ymr1p and the synaptojanin-like phosphatases Sjl2p and Sjl3p in regulation of phosphatidylinositol 3-phosphate in yeast.

Q68FX6	CLPH_RAT	Casein-like phosphoprotein	19271754	CLPH, a novel casein kinase 2-phosphorylated disordered protein, is specificallya associated with post-meiotic germ cells in rat spermatogenesis.

P76135	YDEO_ECOLI	HTH-type transcriptional regulator ydeO	12399493	Escherichia coli gene expression responsive to levels of the response regulator EvgA.

Q9UBF9	MYOTI_HUMAN	Myotilin	16076904	The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins.

Q9HDX9	SYEM_SCHPO	Glutamyl-tRNA synthetase, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q923K1	TS1R3_RAT	Taste receptor type 1 member 3	11917125	Human receptors for sweet and umami taste.

Q14160	SCRIB_HUMAN	Protein scribble homolog	15975580	hScrib interacts with ZO-2 at the cell-cell junctions of epithelial cells.

Q09472	EP300_HUMAN	Histone acetyltransferase p300	14716005	Dendrite development regulated by CREST, a calcium-regulated transcriptional activator.

P06733	ENOA_HUMAN	Alpha-enolase	10082554	Functional domains of c-myc promoter binding protein 1 involved in transcriptional repression and cell growth regulation.

Q6I9Y2	THOC7_HUMAN	THO complex subunit 7 homolog	15998806	Recruitment of the human TREX complex to mRNA during splicing.

Q9XZT7	TAFAB_DROME	Transcription initiation factor TFIID subunit 10b	11134347	Prodos is a conserved transcriptional regulator that interacts with dTAF(II)16 in Drosophila melanogaster.

O74518	CID12_SCHPO	Poly(A) RNA polymerase cid12	15607976	Two RNAi complexes, RITS and RDRC, physically interact and localize to noncoding centromeric RNAs.

O00291	HIP1_HUMAN	Huntingtin-interacting protein 1	16027218	Huntingtin interacting protein 1 modulates the transcriptional activity of nuclear hormone receptors.

Q8QGC4	PBX1_XENLA	Pre-B-cell leukemia transcription factor 1	16631621	Pbx1 and Meis1 regulate activity of the Xenopus laevis Zic3 promoter through a highly conserved region.

Q9UJX4	APC5_HUMAN	Anaphase-promoting complex subunit 5	9469815	Identification of a cullin homology region in a subunit of the anaphase-promoting complex.

P46671	FAR3_YEAST	Factor arrest protein 3	14562095	Global analysis of protein localization in budding yeast.

Q99MA9	NKX61_MOUSE	Homeobox protein Nkx-6.1	10938085	Transcriptional and translational regulation of beta-cell differentiation factor Nkx6.1.

O75832	PSD10_HUMAN	26S proteasome non-ATPase regulatory subunit 10	19729910	Involvement of the mitochondrial pathway in p53-independent apoptosis induced by p28GANK knockdown in Hep3B cells.

Q27913	GBP_PSESE	Growth-blocking peptide, long form	10928276	Distribution of growth-blocking peptide in the insect central nervous tissue.

P40417	ERKA_DROME	Mitogen-activated protein kinase ERK-A	1378625	Primary structure, expression, and signal-dependent tyrosine phosphorylation of a Drosophila homolog of extracellular signal- regulated kinase.

Q02887	ATG21_YEAST	Autophagy-related protein 21	15103325	Svp1p defines a family of phosphatidylinositol 3,5-bisphosphate effectors.

Q12280	IQG1_YEAST	Ras GTPase-activating-like protein IQG1	11082046	Yeast myosin light chain, Mlc1p, interacts with both IQGAP and class II myosin to effect cytokinesis.

P16471	PRLR_HUMAN	Prolactin receptor	7984244	The X-ray structure of a growth hormone-prolactin receptor complex.

O42963	NUP44_SCHPO	Nucleoporin nup44	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Y8G3	MEX67_SCHPO	mRNA export factor mex67	11073978	Mex67p of Schizosaccharomyces pombe interacts with Rae1p in mediating mRNA export.

Q16134	ETFD_HUMAN	Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial	8306995	Molecular cloning and expression of a cDNA encoding human electron transfer flavoprotein-ubiquinone oxidoreductase.

P40003	VAB2_YEAST	Protein VAB2	10888680	Nucleus-vacuole junctions in Saccharomyces cerevisiae are formed through the direct interaction of Vac8p with Nvj1p.

O54952	BRCA1_RAT	Breast cancer type 1 susceptibility protein homolog	11877378	Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure.

P07758	A1AT1_MOUSE	Alpha-1-antitrypsin 1-1	11961105	Functional diversification during evolution of the murine alpha(1)- proteinase inhibitor family: role of the hypervariable reactive center loop.

Q02577	HEN2_HUMAN	Helix-loop-helix protein 2	1328219	A comparative structural characterization of the human NSCL-1 and NSCL-2 genes. Two basic helix-loop-helix genes expressed in the developing nervous system.

Q12420	SNU66_YEAST	66 kDa U4/U6.U5 small nuclear ribonucleoprotein component	15620657	Ubiquitin-like protein Hub1 is required for pre-mRNA splicing and localization of an essential splicing factor in fission yeast.

Q9QXK9	SH22A_MOUSE	SH2 domain-containing protein 2A	10553045	Lad, an adapter protein interacting with the SH2 domain of p56lck, is required for T cell activation.

Q61214	DYR1A_MOUSE	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	9070862	The murine Dyrk protein maps to chromosome 16, localizes to the nucleus, and can form multimers.

P35133	UBC10_ARATH	Ubiquitin-conjugating enzyme E2 10	16461280	The E3 ubiquitin ligase BIG BROTHER controls arabidopsis organ size in a dosage-dependent manner.

Q92989	CLP1_HUMAN	Polyribonucleotide 5'-hydroxyl-kinase Clp1	8896421	AF10 is split by MLL and HEAB, a human homolog to a putative Caenorhabditis elegans ATP/GTP-binding protein in an invins(10;11)(p12;q23q12).

Q62655	ITF2_RAT	Transcription factor 4	7913462	Isolation of two E-box binding factors that interact with the rat tyrosine hydroxylase enhancer.

Q13322	GRB10_HUMAN	Growth factor receptor-bound protein 10	15060076	Grb10 prevents Nedd4-mediated vascular endothelial growth factor receptor-2 degradation.

Q9Y383	LC7L2_HUMAN	Putative RNA-binding protein Luc7-like 2	19574390	Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing.

Q38824	IAA6_ARATH	Auxin-responsive protein IAA6	8624510	Two dominant photomorphogenic mutations of Arabidopsis thaliana identified as suppressor mutations of hy2.

P40851	AXL1_YEAST	Putative protease AXL1	12176366	Subcellular localization of Axl1, the cell type-specific regulator of polarity.

Q12959	DLG1_HUMAN	Disks large homolog 1	10656683	The APC-hDLG complex negatively regulates cell cycle progression from the G0/G1 to S phase.

P17136	RSMB_RAT	Small nuclear ribonucleoprotein-associated protein B	2532363	Isolation of cDNA clones encoding small nuclear ribonucleoparticle- associated proteins with different tissue specificities.

P21672	RIR3_YEAST	Ribonucleoside-diphosphate reductase large chain 2	11893751	Yeast DNA damage-inducible Rnr3 has a very low catalytic activity strongly stimulated after the formation of a cross-talking Rnr1/Rnr3 complex.

Q95YM8	MBLK1_APIME	Mushroom body large-type Kenyon cell-specific protein 1	12637500	The activity of Mblk-1, a mushroom body-selective transcription factor from the honeybee, is modulated by the ras/MAPK pathway.

P87245	KMS1_SCHPO	Karyogamy meiotic segregation protein 1	16111942	Hrs1p/Mcp6p on the meiotic SPB organizes astral microtubule arrays for oscillatory nuclear movement.

Q6GV12	KDSR_MOUSE	3-ketodihydrosphingosine reductase	15328338	FVT-1 is a mammalian 3-ketodihydrosphingosine reductase with an active site that faces the cytosolic side of the endoplasmic reticulum membrane.

Q64520	KGUA_MOUSE	Guanylate kinase	8663313	Cloning, characterization, and modeling of mouse and human guanylate kinases.

Q01714	SP1_RAT	Transcription factor Sp1	19081374	A calcium-dependent switch in a CREST-BRG1 complex regulates activity-dependent gene expression.

P39005	KRE9_YEAST	Cell wall synthesis protein KRE9	8413233	The yeast KRE9 gene encodes an O glycoprotein involved in cell surface beta-glucan assembly.

P08524	FPPS_YEAST	Farnesyl pyrophosphate synthase	2681213	Farnesyl diphosphate synthetase. Molecular cloning, sequence, and expression of an essential gene from Saccharomyces cerevisiae.

P34164	SIP2_YEAST	SNF1 protein kinase subunit beta-2	10990457	beta-subunits of Snf1 kinase are required for kinase function and substrate definition.

Q9NRN7	ADPPT_HUMAN	L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase	12815048	Cloning, expression, and characterization of a human 4'- phosphopantetheinyl transferase with broad substrate specificity.

Q14738	2A5D_HUMAN	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform	8703017	The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm.

Q12416	WHI5_YEAST	G1-specific transcriptional repressor WHI5	15210110	Cln3 activates G1-specific transcription via phosphorylation of the SBF bound repressor Whi5.

Q9NRY6	PLS3_HUMAN	Phospholipid scramblase 3	18256029	Identification of Alix-type and non-Alix-type ALG-2-binding sites in human phospholipid scramblase 3: differential binding to an alternatively spliced isoform and amino acid-substituted mutants.

P34219	TOD6_YEAST	Transcriptional regulatory protein TOD6	19111667	A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters.

Q9M2J9	BET11_ARATH	Bet1-like SNARE 1-1	11445081	AtBS14a and AtBS14b, two Bet1/Sft1-like SNAREs from Arabidopsis thaliana that complement mutations in the yeast SFT1 gene.

O04017	NAC98_ARATH	Protein CUP-SHAPED COTYLEDON 2	9212461	Genes involved in organ separation in Arabidopsis: an analysis of the cup-shaped cotyledon mutant.

Q9P1T7	MDFIC_HUMAN	MyoD family inhibitor domain-containing protein	16260749	Direct interaction of the human I-mfa domain-containing protein, HIC, with HIV-1 Tat results in cytoplasmic sequestration and control of Tat activity.

P20340	RAB6A_HUMAN	Ras-related protein Rab-6A	18243103	Rab and Arl GTPase family members cooperate in the localization of the golgin GCC185.

O00501	CLD5_HUMAN	Claudin-5	9192844	Identification, characterization, and precise mapping of a human gene encoding a novel membrane-spanning protein from the 22q11 region deleted in velo-cardio-facial syndrome.

O15379	HDAC3_HUMAN	Histone deacetylase 3	11931768	The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2.

Q14683	SMC1A_HUMAN	Structural maintenance of chromosomes protein 1A	11076961	Characterization of vertebrate cohesin complexes and their regulation in prophase.

P25801	RBTN2_MOUSE	Rhombotin-2	9001422	Elf-2, a rhombotin-2 binding ets transcription factor: discovery and potential role in T cell leukemia.

Q9LMI0	TPS7_ARATH	Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 7	11520870	Trehalose metabolism in Arabidopsis: occurrence of trehalose and molecular cloning and characterization of trehalose-6-phosphate synthase homologues.

Q08732	HRK1_YEAST	Serine/threonine-protein kinase HRK1	14562095	Global analysis of protein localization in budding yeast.

O60563	CCNT1_HUMAN	Cyclin-T1	12944466	The human I-mfa domain-containing protein, HIC, interacts with cyclin T1 and modulates P-TEFb-dependent transcription.

Q09160	1A80_HUMAN	HLA class I histocompatibility antigen, A-80 alpha chain	8188325	Characterization of a new and highly distinguishable HLA-A allele in a Spanish family.

P53115	INO80_YEAST	Putative DNA helicase INO80	10952318	A chromatin remodelling complex involved in transcription and DNA processing.

Q9WTS4	TEN1_MOUSE	Teneurin-1	10225957	Mouse ten-m/Odz is a new family of dimeric type II transmembrane proteins expressed in many tissues.

Q9WVI9	JIP1_MOUSE	C-Jun-amino-terminal kinase-interacting protein 1	11912189	Interaction of Alzheimer's beta-amyloid precursor family proteins with scaffold proteins of the JNK signaling cascade.

Q9H0D6	XRN2_HUMAN	5'-3' exoribonuclease 2	12429849	Functional proteomic analysis of human nucleolus.

Q9Z2J9	RUNX2_RAT	Runt-related transcription factor 2	9651525	Genomic structure and isoform expression of the mouse, rat and human Cbfa1/Osf2 transcription factor.

Q12067	ATX2_YEAST	Metal homeostasis factor ATX2	8887660	Suppression of oxidative damage by Saccharomyces cerevisiae ATX2, which encodes a manganese-trafficking protein that localizes to Golgi- like vesicles.

Q8K4H1	AFMID_MOUSE	Probable arylformamidase	12007602	Kynurenine formamidase: determination of primary structure and modeling-based prediction of tertiary structure and catalytic triad.

Q9ERS5	PKHA2_MOUSE	Pleckstrin homology domain-containing family A member 2	11001876	Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities.

P23748	MPIP_YEAST	M-phase inducer phosphatase	2649252	Conservation of mitotic controls in fission and budding yeasts.

Q9Y1I2	VP33A_DROME	Vacuolar protein sorting-associated protein 33A	10549280	A role for the deep orange and carnation eye color genes in lysosomal delivery in Drosophila.

Q9LQT8	GAI_ARATH	DELLA protein GAI	9237632	Sequence and characterization of two Arabidopsis thaliana cDNAs isolated by functional complementation of a yeast gln3 gdh1 mutant.

P32480	HIR2_YEAST	Protein HIR2	16449659	Evidence that Spt2/Sin1, an HMG-like factor, plays roles in transcription elongation, chromatin structure, and genome stability in Saccharomyces cerevisiae.

P60953	CDC42_HUMAN	Cell division control protein 42 homolog	11260256	Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42 to atypical protein kinase C.

Q9VYS4	GLD2B_DROME	Poly(A) RNA polymerase gld-2 homolog B	18434412	PAP- and GLD-2-type poly(A) polymerases are required sequentially in cytoplasmic polyadenylation and oogenesis in Drosophila.

Q9FLB1	PYL5_ARATH	Abscisic acid receptor PYL5	19624469	Modulation of drought resistance by the abscisic acid receptor PYL5 through inhibition of clade A PP2Cs.

O75031	HSF2B_HUMAN	Heat shock factor 2-binding protein	9651507	Novel testis-specific protein that interacts with heat shock factor 2.

Q9UBE8	NLK_HUMAN	Serine/threonine-protein kinase NLK	15004007	Role of the TAK1-NLK-STAT3 pathway in TGF-beta-mediated mesoderm induction.

P17157	PHO85_YEAST	Cyclin-dependent protein kinase PHO85	16455487	Mapping pathways and phenotypes by systematic gene overexpression.

Q9Y5S8	NOX1_HUMAN	NADPH oxidase 1	10615049	A mammalian H+ channel, generated through alternative splicing of the NADPH oxidase homolog NOH-1.

P21374	ISY1_YEAST	Pre-mRNA-splicing factor ISY1	10094305	The identification and characterization of a novel splicing protein, Isy1p, of Saccharomyces cerevisiae.

Q96SB4	SRPK1_HUMAN	Serine/threonine-protein kinase SRPK1	15034300	Identification of toposome, a novel multisubunit complex containing topoisomerase IIalpha.

O14925	TIM23_HUMAN	Mitochondrial import inner membrane translocase subunit Tim23	10339406	Genetic and structural characterization of the human mitochondrial inner membrane translocase.

P36683	ACON2_ECOLI	Aconitate hydratase 2	8932712	The second aconitase (AcnB) of Escherichia coli.

Q42093	AB2C_ARATH	ABC transporter C family member 2	9490749	AtMRP2, an Arabidopsis ATP-binding cassette transporter able to transport glutathione S-conjugates and chlorophyll catabolites: functional comparisons with AtMRP1.

Q08013	SSRG_RAT	Translocon-associated protein subunit gamma	7916687	A tetrameric complex of membrane proteins in the endoplasmic reticulum.

P41214	LIGA_HUMAN	Ligatin	2482295	Molecular cloning of the cDNA for ligatin.

P29539	RIF1_YEAST	Telomere length regulator protein RIF1	9087429	A novel Rap1p-interacting factor, Rif2p, cooperates with Rif1p to regulate telomere length in Saccharomyces cerevisiae.

O94458	YFFH_SCHPO	Uncharacterized derlin-like protein C1687.17c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O55005	ROBO1_RAT	Roundabout homolog 1	9458045	Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors.

P38785	GIC1_YEAST	GTPase-interacting component 1	9367979	The Cdc42 GTPase-associated proteins Gic1 and Gic2 are required for polarized cell growth in Saccharomyces cerevisiae.

Q8TE73	DYH5_HUMAN	Dynein heavy chain 5, axonemal	8812413	Multiple mouse chromosomal loci for dynein-based motility.

Q9BSW2	EFC4B_HUMAN	EF-hand calcium-binding domain-containing protein 4B	20418871	A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cells.

O22446	HDA19_ARATH	Histone deacetylase 19	16699543	Arabidopsis thaliana histone deacetylase 1 (AtHD1) is localized in euchromatic regions and demonstrates histone deacetylase activity in vitro.

Q9ULW2	FZD10_HUMAN	Frizzled-10	10448064	Molecular cloning of Frizzled-10, a novel member of the Frizzled gene family.

Q12981	SEC20_HUMAN	Vesicle transport protein SEC20	15272311	Involvement of BNIP1 in apoptosis and endoplasmic reticulum membrane fusion.

Q8IM00	YPF03_PLAF7	Uncharacterized protein PF14_0093	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

P05630	ATPD_BOVIN	ATP synthase subunit delta, mitochondrial	1827992	Identification of the subunits of F1F0-ATPase from bovine heart mitochondria.

Q39081	CAL_ARATH	Transcription factor CAULIFLOWER	10648231	Redundant regulation of meristem identity and plant architecture by FRUITFULL, APETALA1 and CAULIFLOWER.

P98194	AT2C1_HUMAN	Calcium-transporting ATPase type 2C member 1	10615129	Mutations in ATP2C1, encoding a calcium pump, cause Hailey-Hailey disease.

Q17339	GLD1_CAEEL	Female germline-specific tumor suppressor gld-1	11562350	Identification of in vivo mRNA targets of GLD-1, a maxi-KH motif containing protein required for C. elegans germ cell development.

Q96RQ3	MCCA_HUMAN	Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial	11401427	Human biotin-containing subunit of 3-methylcrotonyl-CoA carboxylase gene (MCCA): cDNA sequence, genomic organization, localization to chromosomal band 3q27, and expression.

P00505	AATM_HUMAN	Aspartate aminotransferase, mitochondrial	9537447	Ethanol up-regulates fatty acid uptake and plasma membrane expression and export of mitochondrial aspartate aminotransferase in HepG2 cells.

O94660	NIT2_SCHPO	Probable hydrolase nit2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8VCZ6	SGSM3_MOUSE	Small G protein signaling modulator 3	15709751	Novel rab GAP-like protein, CIP85, interacts with connexin43 and induces its degradation.

Q9SYU4	PEX10_ARATH	Peroxisome biogenesis factor 10	12883010	AthPEX10, a nuclear gene essential for peroxisome and storage organelle formation during Arabidopsis embryogenesis.

P35573	GDE_HUMAN	Glycogen debranching enzyme	1374391	Molecular cloning and nucleotide sequence of cDNA encoding human muscle glycogen debranching enzyme.

Q91848	SIAM_XENLA	Homeobox protein siamois	8898219	The homeobox gene Siamois is a target of the Wnt dorsalisation pathway and triggers organiser activity in the absence of mesoderm.

Q9BYG5	PAR6B_HUMAN	Partitioning defective 6 homolog beta	12725730	Mammalian Lgl forms a protein complex with PAR-6 and aPKC independently of PAR-3 to regulate epithelial cell polarity.

P09099	XYLB_ECOLI	Xylulose kinase	6320721	Cloning and sequencing of the xylose isomerase and xylulose kinase genes of Escherichia coli.

Q8BKT6	TSN12_MOUSE	Tetraspanin-12	19837033	TSPAN12 regulates retinal vascular development by promoting Norrin- but not Wnt-induced FZD4/beta-catenin signaling.

O94488	MBO1_SCHPO	Microtubule organizer protein 1	15120067	Microtubule nucleation at non-spindle pole body microtubule- organizing centers requires fission yeast centrosomin-related protein mod20p.

Q1PDW5	FTSH6_ARATH	ATP-dependent zinc metalloprotease FTSH 6, chloroplastic	16157880	AtFtsH6 is involved in the degradation of the light-harvesting complex II during high-light acclimation and senescence.

Q8T7K0	ALIX_DICDI	ALG-2 interacting protein X	15276209	DdAlix, an Alix/AIP1 homolog in Dictyostelium discoideum, is required for multicellular development under low Ca2+ conditions.

Q9JI44	DMAP1_MOUSE	DNA methyltransferase 1-associated protein 1	10888872	DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci.

Q9Z2H7	GIPC2_MOUSE	PDZ domain-containing protein GIPC2	10318831	A PDZ protein regulates the distribution of the transmembrane semaphorin, M-SemF.

Q9VTK2	POMT1_DROME	Protein O-mannosyltransferase 1	15271988	The twisted abdomen phenotype of Drosophila POMT1 and POMT2 mutants coincides with their heterophilic protein O-mannosyltransferase activity.

Q4PIR3	NSE2_SCHPO	E3 SUMO-protein ligase nse2	15331764	Nse1, Nse2, and a novel subunit of the Smc5-Smc6 complex, Nse3, play a crucial role in meiosis.

Q9VQI9	AFF4_DROME	AF4/FMR2 family member 4	11171404	Transcriptional regulation of cytoskeletal functions and segmentation by a novel maternal pair-rule gene, lilliputian.

Q6QA69	ABHD5_RAT	1-acylglycerol-3-phosphate O-acyltransferase ABHD5	15136565	CGI-58 interacts with perilipin and is localized to lipid droplets. Possible involvement of CGI-58 mislocalization in Chanarin-Dorfman syndrome.

Q9ET32	BGAT1_RAT	Histo-blood group ABO system transferase 1	11842091	Blood group A glycosyltransferase occurring as alleles with high sequence difference is transiently induced during a Nippostrongylus brasiliensis parasite infection.

P40917	YAP4_YEAST	AP-1-like transcription factor YAP4	9559673	Yeast putative transcription factors involved in salt tolerance.

Q63627	SFR15_RAT	Splicing factor, arginine/serine-rich 15	8692929	The C-terminal domain of the largest subunit of RNA polymerase II interacts with a novel set of serine/arginine-rich proteins.

Q13042	CDC16_HUMAN	Cell division cycle protein 16 homolog	7736578	CDC27Hs colocalizes with CDC16Hs to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition.

Q8GZM7	PIF1_ARATH	Transcription factor PIF1	18539749	Light-induced phosphorylation and degradation of the negative regulator PHYTOCHROME-INTERACTING FACTOR1 from Arabidopsis depend upon its direct physical interactions with photoactivated phytochromes.

Q15723	ELF2_HUMAN	ETS-related transcription factor Elf-2	14970218	Isoforms of the Ets transcription factor NERF/ELF-2 physically interact with AML1 and mediate opposing effects on AML1-mediated transcription of the B cell-specific blk gene.

Q9Y6M1	IF2B2_HUMAN	Insulin-like growth factor 2 mRNA-binding protein 2	9891060	A family of insulin-like growth factor II mRNA-binding proteins represses translation in late development.

O42847	YFH9_SCHPO	Uncharacterized RNA-binding protein C23A1.09	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q70IV5	SYNEM_MOUSE	Synemin	17356066	Synemin is expressed in reactive astrocytes in neurotrauma and interacts differentially with vimentin and GFAP intermediate filament networks.

Q9LL84	DNLI4_ARATH	DNA ligase 4	11029705	Arabidopsis DNA ligase IV is induced by gamma-irradiation and interacts with an Arabidopsis homologue of the double strand break repair protein XRCC4.

Q03941	CAB5_YEAST	Dephospho-CoA kinase CAB5	19266201	Genetic analysis of coenzyme A biosynthesis in the yeast Saccharomyces cerevisiae: identification of a conditional mutation in the pantothenate kinase gene CAB1.

P38793	TRM5_YEAST	tRNA (guanine-N(1)-)-methyltransferase	11226173	A primordial tRNA modification required for the evolution of life?

P00927	THDH_YEAST	Threonine dehydratase, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

Q5FBB7	SGOL1_HUMAN	Shugoshin-like 1	17621308	Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis.

O43502	RA51C_HUMAN	DNA repair protein RAD51 homolog 3	9469824	Isolation and characterization of RAD51C, a new human member of the RAD51 family of related genes.

P22735	TGM1_HUMAN	Protein-glutamine gamma-glutamyltransferase K	1979171	Primary structure of keratinocyte transglutaminase.

P15873	PCNA_YEAST	Proliferating cell nuclear antigen	16782870	Interaction between PCNA and diubiquitinated Mcm10 is essential for cell growth in budding yeast.

Q9WVM1	RGAP1_MOUSE	Rac GTPase-activating protein 1	11287179	Mice with a homozygous gene trap vector insertion in mgcRacGAP die during pre-implantation development.

Q9Y3C8	UFC1_HUMAN	Ubiquitin-fold modifier-conjugating enzyme 1	15071506	A novel protein-conjugating system for Ufm1, a ubiquitin-fold modifier.

P13607	ATNA_DROME	Sodium/potassium-transporting ATPase subunit alpha	9680312	The Drosophila Na,K-ATPase alpha-subunit gene: gene structure, promoter function and analysis of a cold-sensitive recessive-lethal mutation.

Q8R4G0	NTNG1_MOUSE	Netrin-G1	10964959	Netrin-G1: a novel glycosyl phosphatidylinositol-linked mammalian netrin that is functionally divergent from classical netrins.

P00572	KTHY_YEAST	Thymidylate kinase	6088527	The CDC8 gene of yeast encodes thymidylate kinase.

Q6B2C0	MTAL2_YEAST	Mating-type protein ALPHA2	7569974	Crystal structure of the MATa1/MAT alpha 2 homeodomain heterodimer bound to DNA.

P18775	DMSA_ECOLI	Anaerobic dimethyl sulfoxide reductase chain A	8125918	Multiple pathways of electron transfer in dimethyl sulfoxide reductase of Escherichia coli.

Q9US09	BTN1_SCHPO	Protein btn1	16291725	btn1, the Schizosaccharomyces pombe homologue of the human Batten disease gene CLN3, regulates vacuole homeostasis.

P40341	YTA12_YEAST	Mitochondrial respiratory chain complexes assembly protein YTA12	8681382	The YTA10-12 complex, an AAA protease with chaperone-like activity in the inner membrane of mitochondria.

Q9WV87	NOX1_RAT	NADPH oxidase 1	10485709	Cell transformation by the superoxide-generating oxidase Mox1.

Q9NT62	ATG3_HUMAN	Ubiquitin-like-conjugating enzyme ATG3	11825910	Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p.

P40046	VTC1_YEAST	Vacuolar transporter chaperone 1	11823419	The Vtc proteins in vacuole fusion: coupling NSF activity to V(0) trans-complex formation.

P09416	MYC_RAT	Myc proto-oncogene protein	3306601	Characterization of rat c-myc and adjacent regions.

Q9P7Q7	MAK1_SCHPO	Peroxide stress-activated histidine kinase mak1	11758939	Genetic analysis of the His-to-Asp phosphorelay implicated in mitotic cell cycle control: involvement of histidine-kinase genes of Schizosaccharomyces pombe.

Q12242	RUP1_YEAST	UBA domain-containing protein RUP1	15933713	The Rsp5 ubiquitin ligase is coupled to and antagonized by the Ubp2 deubiquitinating enzyme.

Q03419	IZH1_YEAST	ADIPOR-like receptor IZH1	14562095	Global analysis of protein localization in budding yeast.

P40459	PANC_YEAST	Pantoate--beta-alanine ligase	14562095	Global analysis of protein localization in budding yeast.

Q9NX18	SDHF2_HUMAN	Succinate dehydrogenase assembly factor 2, mitochondrial	19628817	SDH5, a gene required for flavination of succinate dehydrogenase, is mutated in paraganglioma.

O43041	TRS23_SCHPO	Transport protein particle subunit trs23	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q03868	SPO71_YEAST	Sporulation-specific protein 71	9784122	The transcriptional program of sporulation in budding yeast.

P20340	RAB6A_HUMAN	Ras-related protein Rab-6A	2501306	The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion.

P43353	AL3B1_HUMAN	Aldehyde dehydrogenase family 3 member B1	7828891	Cloning of a cDNA encoding human ALDH7, a new member of the aldehyde dehydrogenase family.

Q10588	BST1_HUMAN	ADP-ribosyl cyclase 2	8202488	BST-1, a surface molecule of bone marrow stromal cell lines that facilitates pre-B-cell growth.

P36533	RM39_YEAST	54S ribosomal protein L39, mitochondrial	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

P35638	DDIT3_HUMAN	DNA damage-inducible transcript 3 protein	1339368	Isolation, characterization and chromosomal localization of the human GADD153 gene.

Q92212	STE20_CANAL	Serine/threonine-protein kinase CST20	12453219	A conserved mitogen-activated protein kinase pathway is required for mating in Candida albicans.

Q90ZH9	S17AB_XENLA	Transcription factor Sox-17-alpha-B	12062811	Expression and characterization of Xenopus laevis SRY-related cDNAs, xSox17alpha1, xSox17alpha2, xSox18alpha and xSox18beta.

Q9NXV6	CARF_HUMAN	CDKN2A-interacting protein	12154087	CARF is a novel protein that cooperates with mouse p19ARF (human p14ARF) in activating p53.

P40023	EDC2_YEAST	Enhancer of mRNA-decapping protein 2	12554867	The enhancer of decapping proteins, Edc1p and Edc2p, bind RNA and stimulate the activity of the decapping enzyme.

P19524	MYO2_YEAST	Myosin-2	11733545	A role for Vps1p, actin, and the Myo2p motor in peroxisome abundance and inheritance in Saccharomyces cerevisiae.

Q00578	RAD25_YEAST	DNA repair helicase RAD25	7961739	RNA polymerase transcription factor IIH holoenzyme from yeast.

P78368	KC1G2_HUMAN	Casein kinase I isoform gamma-2	9403068	Cloning and chromosomal mapping of human casein kinase I gamma 2 (CSNK1G2).

P33763	S10A5_HUMAN	Protein S100-A5	19536568	Solution structure and dynamics of S100A5 in the apo and Ca2+-bound states.

P14740	DPP4_RAT	Dipeptidyl peptidase 4	2563382	Primary structure of rat liver dipeptidyl peptidase IV deduced from its cDNA and identification of the NH2-terminal signal sequence as the membrane-anchoring domain.

O64425	RMA1_ARATH	E3 ubiquitin-protein ligase RMA1	9664717	RMA1, an Arabidopsis thaliana gene whose cDNA suppresses the yeast sec15 mutation, encodes a novel protein with a RING finger motif and a membrane anchor.

O14757	CHK1_HUMAN	Serine/threonine-protein kinase Chk1	9278511	Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25.

O74201	UBC2_CANAL	Ubiquitin-conjugating enzyme E2 2	10712706	Rad6p represses yeast-hypha morphogenesis in the human fungal pathogen Candida albicans.

Q03792	RIM13_YEAST	Calpain-like protease 1	9928935	The protease activity of a calpain-like cysteine protease in Saccharomyces cerevisiae is required for alkaline adaptation and sporulation.

Q08209	PP2BA_HUMAN	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	8524402	Crystal structures of human calcineurin and the human FKBP12-FK506- calcineurin complex.

P61923	COPZ1_HUMAN	Coatomer subunit zeta-1	11056392	Identification and characterization of novel isoforms of COP I subunits.

P25105	PTAFR_HUMAN	Platelet-activating factor receptor	1657923	Molecular cloning and expression of platelet-activating factor receptor from human leukocytes.

P55317	FOXA1_HUMAN	Hepatocyte nuclear factor 3-alpha	16087863	Location analysis of estrogen receptor alpha target promoters reveals that FOXA1 defines a domain of the estrogen response.

Q9Y697	NFS1_HUMAN	Cysteine desulfurase, mitochondrial	9885568	Targeting of a human iron-sulfur cluster assembly enzyme, nifs, to different subcellular compartments is regulated through alternative AUG utilization.

P20795	VPS33_YEAST	Vacuolar protein sorting-associated protein 33	2183024	The SLP1 gene of Saccharomyces cerevisiae is essential for vacuolar morphogenesis and function.

Q13158	FADD_HUMAN	Protein FADD	10442631	PED/PEA-15: an anti-apoptotic molecule that regulates FAS/TNFR1- induced apoptosis.

O60174	SFC6_SCHPO	Transcription factor tau subunit sfc6	16751097	A role for TFIIIC transcription factor complex in genome organization.

Q15615	OR4D1_HUMAN	Olfactory receptor 4D1	9119360	Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species.

P38074	HMT1_YEAST	HNRNP arginine N-methyltransferase	8647869	The predominant protein-arginine methyltransferase from Saccharomyces cerevisiae.

Q9NBD7	CLASP_DROME	CLIP-associating protein	10899121	Mast, a conserved microtubule-associated protein required for bipolar mitotic spindle organization.

Q12188	REC8_YEAST	Meiotic recombination protein REC8	10412984	A central role for cohesins in sister chromatid cohesion, formation of axial elements, and recombination during yeast meiosis.

P19018	TRA2_DROME	Transformer-2 sex-determining protein	2116360	Alternative splicing of the sex determination gene transformer-2 is sex-specific in the germ line but not in the soma.

O00291	HIP1_HUMAN	Huntingtin-interacting protein 1	14732715	HIP1 and HIP1r stabilize receptor tyrosine kinases and bind 3- phosphoinositides via epsin N-terminal homology domains.

P35680	HNF1B_HUMAN	Hepatocyte nuclear factor 1-beta	1677179	Two members of an HNF1 homeoprotein family are expressed in human liver.

Q9H1C4	UN93B_HUMAN	Protein unc-93 homolog B1	18082565	Assessing the function of human UNC-93B in Toll-like receptor signaling and major histocompatibility complex II response.

P46655	SYEC_YEAST	Glutamyl-tRNA synthetase, cytoplasmic	14562095	Global analysis of protein localization in budding yeast.

Q9HD36	B2L10_HUMAN	Bcl-2-like protein 10	11278245	Bcl-B, a novel Bcl-2 family member that differentially binds and regulates Bax and Bak.

Q9NYA1	SPHK1_HUMAN	Sphingosine kinase 1	20577214	Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2.

P21786	ALLT_MANSE	Allatotropin	8774701	Molecular characterization and expression analysis of Manduca sexta allatotropin.

Q8IW19	APLF_HUMAN	Aprataxin and PNK-like factor	18172500	Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins.

P55161	NCKP1_RAT	Nck-associated protein 1	8605018	Molecular cloning of p125Nap1, a protein that associates with an SH3 domain of Nck.

Q62205	SCN9A_MOUSE	Sodium channel protein type 9 subunit alpha	15314237	Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1) in acute and inflammatory pain.

P00374	DYR_HUMAN	Dihydrofolate reductase	12096917	Atomic structures of human dihydrofolate reductase complexed with NADPH and two lipophilic antifolates at 1.09 A and 1.05 A resolution.

O08651	SERA_RAT	D-3-phosphoglycerate dehydrogenase	9163325	Cloning, sequencing and expression of rat liver 3-phosphoglycerate dehydrogenase.

P29558	RBMS1_HUMAN	RNA-binding motif, single-stranded-interacting protein 1	7838710	Molecular cloning of MSSP-2, a c-myc gene single-strand binding protein: characterization of binding specificity and DNA replication activity.

P70550	RAB8B_RAT	Ras-related protein Rab-8B	8799816	Identification of a novel member of the Rab8 family from the rat basophilic leukaemia cell line, RBL.2H3.

Q94F00	IMPL1_ARATH	Phosphatase IMPL1, chloroplastic	19339506	VTC4 is a bifunctional enzyme that affects myoinositol and ascorbate biosynthesis in plants.

Q9Z0G2	SRPK3_MOUSE	Serine/threonine-protein kinase SRPK3	16140986	Centronuclear myopathy in mice lacking a novel muscle-specific protein kinase transcriptionally regulated by MEF2.

O48538	RBOHF_ARATH	Respiratory burst oxidase homolog protein F	16961732	Ethylene-induced stomatal closure in Arabidopsis occurs via AtrbohF- mediated hydrogen peroxide synthesis.

Q9H0E2	TOLIP_HUMAN	Toll-interacting protein	10854325	Tollip, a new component of the IL-1R1 pathway, links IRAK to the IL-1 receptor.

Q6A051	ATRN1_MOUSE	Attractin-like protein 1	14531729	Characterization of a novel binding partner of the melanocortin-4 receptor: attractin-like protein.

Q9P2X0	DPM3_HUMAN	Dolichol-phosphate mannosyltransferase subunit 3	10835346	Human dolichol-phosphate-mannose synthase consists of three subunits, DPM1, DPM2 and DPM3.

Q8K299	SCAR5_MOUSE	Scavenger receptor class A member 5	16407294	Identification and characterization of murine SCARA5, a novel class A scavenger receptor that is expressed by populations of epithelial cells.

Q09666	AHNK_HUMAN	Neuroblast differentiation-associated protein AHNAK	1608957	A human gene (AHNAK) encoding an unusually large protein with a 1.2- microns polyionic rod structure.

Q62448	IF4G2_MOUSE	Eukaryotic translation initiation factor 4 gamma 2	9030685	A novel translational repressor mRNA is edited extensively in livers containing tumors caused by the transgene expression of the apoB mRNA- editing enzyme.

Q9C9Q8	PMTT_ARATH	Probable pectin methyltransferase QUA2	17425712	Homogalacturonan synthesis in Arabidopsis thaliana requires a Golgi- localized protein with a putative methyltransferase domain.

Q9UHC3	ACCN3_HUMAN	Amiloride-sensitive cation channel 3	9571199	Molecular cloning of a DEG/ENaC sodium channel cDNA from human testis.

Q9NR09	BIRC6_HUMAN	Baculoviral IAP repeat-containing protein 6	10544019	A human IAP-family gene, apollon, expressed in human brain cancer cells.

P30658	CBX2_MOUSE	Chromobox protein homolog 2	9312051	Ring1A is a transcriptional repressor that interacts with the Polycomb-M33 protein and is expressed at rhombomere boundaries in the mouse hindbrain.

Q92556	ELMO1_HUMAN	Engulfment and cell motility protein 1	12029088	Identification of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASP), WASP-interacting protein (WIP), and ELMO1.

Q59H18	TNI3K_HUMAN	Serine/threonine-protein kinase TNNI3K	12721663	Cloning and characterization of a novel cardiac-specific kinase that interacts specifically with cardiac troponin I.

P84681	SC37_TITCA	Toxin Tc37	15025998	Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

P97675	ENPP3_RAT	Ectonucleotide pyrophosphatase/phosphodiesterase family member 3	9096610	Biochemical and molecular identification of distinct forms of alkaline phosphodiesterase I expressed on the apical and basolateral plasma membrane surfaces of rat hepatocytes.

P40238	TPOR_HUMAN	Thrombopoietin receptor	8020956	Structure and transcription of the human c-mpl gene (MPL).

Q20085	PMY11_CAEEL	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase wee-1.1	10209262	A Caenorhabditis elegans wee1 homolog is expressed in a temporally and spatially restricted pattern during embryonic development.

Q6EH50	RIP4_PHYHE	Heterotepalin-4	17258249	Isolation and characterization of heterotepalins, type 1 ribosome- inactivating proteins from Phytolacca heterotepala leaves.

Q9JKL5	TESC_MOUSE	Tescalcin	11145610	Tescalcin, a novel gene encoding a putative EF-hand Ca(2+)-binding protein, Col9a3, and renin are expressed in the mouse testis during the early stages of gonadal differentiation.

P02452	CO1A1_HUMAN	Collagen alpha-1(I) chain	1874719	Substitutions for glycine alpha 1-637 and glycine alpha 2-694 of type I procollagen in lethal osteogenesis imperfecta. The conformational strain on the triple helix introduced by a glycine substitution can be transmitted along the helix.

Q15438	CYH1_HUMAN	Cytohesin-1	11867758	Cybr, a cytokine-inducible protein that binds cytohesin-1 and regulates its activity.

P13360	GLAS_DROME	Protein glass	2770860	The glass gene encodes a zinc-finger protein required by Drosophila photoreceptor cells.

P43612	SA155_YEAST	SIT4-associating protein SAP155	8649382	The SAPs, a new family of proteins, associate and function positively with the SIT4 phosphatase.

Q9UN30	SCML1_HUMAN	Sex comb on midleg-like protein 1	9570953	Characterization of SCML1, a new gene in Xp22, with homology to developmental polycomb genes.

P53115	INO80_YEAST	Putative DNA helicase INO80	10361278	The product of the SNF2/SWI2 paralogue INO80 of Saccharomyces cerevisiae required for efficient expression of various yeast structural genes is part of a high-molecular-weight protein complex.

Q14164	IKKE_HUMAN	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	20188669	SUMOylation-dependent localization of IKKepsilon in PML nuclear bodies is essential for protection against DNA-damage-triggered cell death.

Q55DL0	DPYS_DICDI	Dihydropyrimidinase	12626710	Dihydropyrimidine amidohydrolases and dihydroorotases share the same origin and several enzymatic properties.

Q41932	PSBQ2_ARATH	Oxygen-evolving enhancer protein 3-2, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q07407	FGFR1_DROME	Fibroblast growth factor receptor homolog 1	8330538	Two FGF-receptor homologues of Drosophila: one is expressed in mesodermal primordium in early embryos.

P40200	TACT_HUMAN	T-cell surface protein tactile	15034010	CD96 (tactile) promotes NK cell-target cell adhesion by interacting with the poliovirus receptor (CD155).

Q8MVR1	GBPC_DICDI	Cyclic GMP-binding protein C	18703517	Intramolecular activation mechanism of the dictyostelium LRRK2- homolog Roco protein GbpC.

P35575	G6PC_HUMAN	Glucose-6-phosphatase	7573034	Genetic basis of glycogen storage disease type 1a: prevalent mutations at the glucose-6-phosphatase locus.

O42601	S17B1_XENLA	Transcription factor Sox-17-beta.1	19003160	Cephalic hedgehog expression is regulated directly by Sox17 in endoderm development of Xenopus laevis.

P69735	RB3GP_RAT	Rab3 GTPase-activating protein catalytic subunit	9733780	Molecular cloning and characterization of the noncatalytic subunit of the Rab3 subfamily-specific GTPase-activating protein.

Q811D0	DLG1_MOUSE	Disks large homolog 1	15277200	Caveolin-3 and SAP97 form a scaffolding protein complex that regulates the voltage-gated potassium channel Kv1.5.

Q9VIS1	CDGAP_DROME	GTPase-activating protein CdGAPr	10842085	Dynamic expression of d-CdGAPr, a novel Drosophila melanogaster gene encoding a GTPase activating protein.

P15372	ARRA_DROME	Phosrestin-2	8316831	Arrestin function in inactivation of G protein-coupled receptor rhodopsin in vivo.

P28301	LYOX_MOUSE	Protein-lysine 6-oxidase	16251195	The Pro-regions of lysyl oxidase and lysyl oxidase-like 1 are required for deposition onto elastic fibers.

Q8TDM6	DLG5_HUMAN	Disks large homolog 5	12657639	Interaction of lp-dlg/KIAA0583, a membrane-associated guanylate kinase family protein, with vinexin and beta-catenin at sites of cell- cell contact.

P14894	CONA_CANGL	Concanavalin-A	15935326	Isolation and characterization of a glucose/mannose/rhamnose-specific lectin from the knife bean Canavalia gladiata.

Q8NBP7	PCSK9_HUMAN	Proprotein convertase subtilisin/kexin type 9	12730697	Mutations in PCSK9 cause autosomal dominant hypercholesterolemia.

Q12270	RBD2_YEAST	Rhomboid protein 2	14562095	Global analysis of protein localization in budding yeast.

Q16706	MA2A1_HUMAN	Alpha-mannosidase 2	8524845	Molecular cloning and expression of cDNAs encoding human alpha- mannosidase II and a previously unrecognized alpha-mannosidase IIx isozyme.

A9ZSY2	TRET1_APILI	Facilitated trehalose transporter Tret1	20035867	The trehalose transporter 1 gene sequence is conserved in insects and encodes proteins with different kinetic properties involved in trehalose import into peripheral tissues.

P05753	RS4_YEAST	40S ribosomal protein S4	6814480	Isolation of seventeen proteins and amino-terminal amino acid sequences of eight proteins from cytoplasmic ribosomes of yeast.

O93529	FOXB1_XENLA	Forkhead box protein B1	15656969	Of fox and frogs: fox (fork head/winged helix) transcription factors in Xenopus development.

O42976	YGZ7_SCHPO	Uncharacterized membrane protein C20F10.07	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UL01	DSE_HUMAN	Dermatan-sulfate epimerase	16505484	Biosynthesis of dermatan sulfate: chondroitin-glucuronate C5- epimerase is identical to SART2.

Q9JMI1	AACS_RAT	Acetoacetyl-CoA synthetase	10682835	cDNA-derived amino acid sequence of acetoacetyl-CoA synthetase from rat liver.

Q9NP61	ARFG3_HUMAN	ADP-ribosylation factor GTPase-activating protein 3	11172815	Functional characterization of novel human ARFGAP3.

P15812	CD1E_HUMAN	T-cell surface glycoprotein CD1e, membrane-associated	2467814	Two classes of CD1 genes.

P09529	INHBB_HUMAN	Inhibin beta B chain	12697670	Differential binding and neutralization of activins A and B by follistatin and follistatin like-3 (FSTL-3/FSRP/FLRG).

Q9LX82	MYB48_ARATH	Transcription factor MYB48	16463103	The MYB transcription factor superfamily of Arabidopsis: expression analysis and phylogenetic comparison with the rice MYB family.

P68133	ACTS_HUMAN	Actin, alpha skeletal muscle	15198992	Evidence for a dominant-negative effect in ACTA1 nemaline myopathy caused by abnormal folding, aggregation and altered polymerization of mutant actin isoforms.

Q07231	ZSC21_MOUSE	Zinc finger and SCAN domain-containing protein 21	1397691	Expression of a mouse zinc finger protein gene in both spermatocytes and oocytes during meiosis.

Q9UUB5	MIS13_SCHPO	Kinetochore protein mis13	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8WW12	PCNP_HUMAN	PEST proteolytic signal-containing nuclear protein	12176013	NIRF, a novel RING finger protein, is involved in cell-cycle regulation.

P38197	YBD6_YEAST	UPF0001 protein YBL036C	12499548	Structure of a yeast hypothetical protein selected by a structural genomics approach.

P16658	SEN2_YEAST	tRNA-splicing endonuclease subunit SEN2	9200603	The yeast tRNA splicing endonuclease: a tetrameric enzyme with two active site subunits homologous to the archaeal tRNA endonucleases.

Q9DEN4	FXD3A_XENLA	Forkhead box protein D3-A	17138566	FoxD3 and Grg4 physically interact to repress transcription and induce mesoderm in Xenopus.

P52298	NCBP2_HUMAN	Nuclear cap-binding protein subunit 2	9111328	Interaction between the human nuclear cap-binding protein complex and hnRNP F.

Q02293	FNTB_RAT	Protein farnesyltransferase subunit beta	1855253	cDNA cloning and expression of the peptide-binding beta subunit of rat p21ras farnesyltransferase, the counterpart of yeast DPR1/RAM1.

Q9Y7Z5	YP04_SCHPO	UPF0121 membrane protein C1539.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P78545	ELF3_HUMAN	ETS-related transcription factor Elf-3	9234700	Isolation and characterization of a novel epithelium-specific transcription factor, ESE-1, a member of the ets family.

Q9USZ5	TRS20_SCHPO	Transport protein particle 20 kDa subunit	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O48653	DPOLA_ORYSJ	DNA polymerase alpha catalytic subunit	9491803	Molecular cloning of the cDNA for the catalytic subunit of plant DNA polymerase alpha and its cell-cycle dependent expression.

P42283	LOLA1_DROME	Longitudinals lacking protein, isoform G	11880341	Lola regulates midline crossing of CNS axons in Drosophila.

O14283	PRR1_SCHPO	Transcription factor prr1	10348908	A fission yeast gene (prr1(+)) that encodes a response regulator implicated in oxidative stress response.

Q18206	NAS36_CAEEL	Zinc metalloproteinase nas-36	15255192	Metalloproteases with EGF, CUB, and thrombospondin-1 domains function in molting of Caenorhabditis elegans.

Q94901	LARK_DROME	RNA-binding protein lark	11560900	Genetic analysis of functional domains within the Drosophila LARK RNA-binding protein.

O23913	AOX1B_ARATH	Alternative oxidase 1b, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

O75385	ULK1_HUMAN	Serine/threonine-protein kinase ULK1	11146101	Interaction of the Unc-51-like kinase and microtubule-associated protein light chain 3 related proteins in the brain: possible role of vesicular transport in axonal elongation.

Q04671	P_HUMAN	P protein	8421497	A gene for the mouse pink-eyed dilution locus and for human type II oculocutaneous albinism.

Q13112	CAF1B_HUMAN	Chromatin assembly factor 1 subunit B	7600578	The p150 and p60 subunits of chromatin assembly factor I: a molecular link between newly synthesized histones and DNA replication.

P29508	SPB3_HUMAN	Serpin B3	7724531	A serine proteinase inhibitor locus at 18q21.3 contains a tandem duplication of the human squamous cell carcinoma antigen gene.

P08151	GLI1_HUMAN	Zinc finger protein GLI1	10806483	Gli regulation by the opposing activities of fused and suppressor of fused.

P32361	IRE1_YEAST	Serine/threonine-protein kinase/endoribonuclease IRE1	1625574	IRE1 encodes a putative protein kinase containing a membrane-spanning domain and is required for inositol phototrophy in Saccharomyces cerevisiae.

Q9UH77	KLHL3_HUMAN	Kelch-like protein 3	10843806	Molecular characterization of KLHL3, a human homologue of the Drosophila kelch gene.

Q6AWW5	Y5262_ARATH	Ankyrin repeat-containing protein At5g02620	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q86VP6	CAND1_HUMAN	Cullin-associated NEDD8-dissociated protein 1	12609982	TIP120A associates with cullins and modulates ubiquitin ligase activity.

Q9UL19	TIG3_HUMAN	Retinoic acid receptor responder protein 3	9843971	Identification and characterization of a retinoid-induced class II tumor suppressor/growth regulatory gene.

P32354	MCM10_YEAST	Minichromosome maintenance protein 10	13680157	Two bipartite NLSs mediate constitutive nuclear localization of Mcm10.

P53040	TAF6_YEAST	Transcription initiation factor TFIID subunit 6	10788514	Identification of two novel TAF subunits of the yeast Saccharomyces cerevisiae TFIID complex.

O75150	BRE1B_HUMAN	E3 ubiquitin-protein ligase BRE1B	16307923	Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation.

Q9WTR8	PHLP1_RAT	PH domain leucine-rich repeat protein phosphatase 1	10570941	SCOP, a novel gene product expressed in a circadian manner in rat suprachiasmatic nucleus.

P15289	ARSA_HUMAN	Arylsulfatase A	2562955	Cloning and expression of human arylsulfatase A.

P68106	FKB1B_HUMAN	Peptidyl-prolyl cis-trans isomerase FKBP1B	7513996	Molecular cloning and expression of a novel human gene that is highly homologous to human FK506-binding protein 12kDa (hFKBP-12) and characterization of two alternatively spliced transcripts.

O70343	PRGC1_MOUSE	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha	18483224	Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex.

P15367	SEC11_YEAST	Signal peptidase complex catalytic subunit SEC11	1846444	Yeast signal peptidase contains a glycoprotein and the Sec11 gene product.

Q03281	HEH2_YEAST	Inner nuclear membrane protein HEH2	16929305	Karyopherin-mediated import of integral inner nuclear membrane proteins.

P53315	SOL4_YEAST	6-phosphogluconolactonase 4	15454531	Division of labor among the yeast Sol proteins implicated in tRNA nuclear export and carbohydrate metabolism.

P21802	FGFR2_HUMAN	Fibroblast growth factor receptor 2	1697263	Cloning and expression of two distinct high-affinity receptors cross- reacting with acidic and basic fibroblast growth factors.

Q8TDC3	BRSK1_HUMAN	BR serine/threonine-protein kinase 1	14976552	LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1.

Q9Z0L8	GGH_MOUSE	Gamma-glutamyl hydrolase	9756990	Cloning of mouse gamma-glutamyl hydrolase in the form of two cDNA variants with different 5' ends and encoding alternate leader peptide sequences.

Q9XV66	UNC80_CAEEL	Protein unc-80	3576211	Genetic analysis of halothane sensitivity in Caenorhabditis elegans.

P22255	CYSQ_ECOLI	3'(2'),5'-bisphosphate nucleotidase cysQ	1729235	cysQ, a gene needed for cysteine synthesis in Escherichia coli K-12 only during aerobic growth.

Q9ESN5	CENPK_MOUSE	Centromere protein K	10996314	Characterization of Solt, a novel SoxLZ/Sox6 binding protein expressed in adult mouse testis.

Q8GYC7	PGL1B_ARATH	PGR5-like protein 1B, chloroplastic	18243102	A complex containing PGRL1 and PGR5 is involved in the switch between linear and cyclic electron flow in Arabidopsis.

Q9UHG0	DCDC2_HUMAN	Doublecortin domain-containing protein 2	10601354	A new antigen recognized by cytolytic T lymphocytes on a human kidney tumor results from reverse strand transcription.

O82798	ARR4_ARATH	Two-component response regulator ARR4	11691995	Interaction of the response regulator ARR4 with phytochrome B in modulating red light signaling.

P00156	CYB_HUMAN	Cytochrome b	6100559	Serendipitous cloning of a mitochondrial cDNA and its polymorphism.

P14207	FOLR2_HUMAN	Folate receptor beta	2605182	Homologous membrane folate binding proteins in human placenta: cloning and sequence of a cDNA.

B2RU80	PTPRB_MOUSE	Receptor-type tyrosine-protein phosphatase beta	10557082	Functional interaction of vascular endothelial-protein-tyrosine phosphatase with the angiopoietin receptor Tie-2.

Q84LH3	WEX_ARATH	Werner Syndrome-like exonuclease	16396834	A conserved and species-specific functional interaction between the Werner syndrome-like exonuclease atWEX and the Ku heterodimer in Arabidopsis.

Q86V81	THOC4_HUMAN	THO complex subunit 4	15998806	Recruitment of the human TREX complex to mRNA during splicing.

P47088	GPI14_YEAST	GPI mannosyltransferase 1	16134120	Characterization of GPI14/YJR013w mutation that induces the cell wall integrity signalling pathway and results in increased protein production in Saccharomyces cerevisiae.

Q9H093	NUAK2_HUMAN	NUAK family SNF1-like kinase 2	15345718	Identification of SNF1/AMP kinase-related kinase as an NF-kappaB- regulated anti-apoptotic kinase involved in CD95-induced motility and invasiveness.

Q9VJ33	NEDD8_DROME	NEDD8	15843622	Requirement of Cul3 for axonal arborization and dendritic elaboration in Drosophila mushroom body neurons.

Q09161	NCBP1_HUMAN	Nuclear cap-binding protein subunit 1	12374755	Large-scale induced fit recognition of an m(7)GpppG cap analogue by the human nuclear cap-binding complex.

P83719	RACYT_RANTE	Ranacyclin-T	14636071	Ranacyclins, a new family of short cyclic antimicrobial peptides: biological function, mode of action and parameters involved in target specificity.

Q9NYD6	HXC10_HUMAN	Homeobox protein Hox-C10	10835276	Selection of homeotic proteins for binding to a human DNA replication origin.

Q9NRY6	PLS3_HUMAN	Phospholipid scramblase 3	10930526	Identification of three new members of the phospholipid scramblase gene family.

Q9SCY5	KINB2_ARATH	SNF1-related protein kinase regulatory subunit beta-2	11522840	Detection of in vivo protein interactions between Snf1-related kinase subunits with intron-tagged epitope-labelling in plants cells.

Q9H2K2	TNKS2_HUMAN	Tankyrase-2	11739745	Role for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeres.

P37267	CBP4_YEAST	Assembly factor CBP4	15759116	Organization of assembly factors Cbp3p and Cbp4p and their effect on bc(1) complex assembly in Saccharomyces cerevisiae.

P06311	KV311_HUMAN	Ig kappa chain V-III region IARC/BL41	2997711	Human immunoglobulin kappa light chain genes of subgroups II and III.

Q3LHL9	WGE_DROME	Protein winged eye	16247005	Involvement of winged eye encoding a chromatin-associated bromo- adjacent homology domain protein in disc specification.

Q8R307	VPS18_MOUSE	Vacuolar protein sorting-associated protein 18 homolog	14668490	Mammalian late vacuole protein sorting orthologues participate in early endosomal fusion and interact with the cytoskeleton.

Q9FMF5	RPT3_ARATH	Root phototropism protein 3	16777956	PHYTOCHROME KINASE SUBSTRATE 1 is a phototropin 1 binding protein required for phototropism.

P61081	UBC12_HUMAN	NEDD8-conjugating enzyme Ubc12	19250909	E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification.

Q16671	AMHR2_HUMAN	Anti-Muellerian hormone type-2 receptor	7493017	Insensitivity to anti-Muellerian hormone due to a mutation in the human anti-Muellerian hormone receptor.

O76031	CLPX_HUMAN	ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial	11003706	Human and mouse mitochondrial orthologs of bacterial ClpX.

Q04491	SEC13_YEAST	Protein transport protein SEC13	8565072	A novel complex of nucleoporins, which includes Sec13p and a Sec13p homolog, is essential for normal nuclear pores.

Q9RXI7	DDRD_DEIRA	DNA damage response protein D	15454524	Analysis of Deinococcus radiodurans's transcriptional response to ionizing radiation and desiccation reveals novel proteins that contribute to extreme radioresistance.

A5HAK0	RNSL3_DANRE	Ribonuclease-like 3	16861230	Ribonucleases and angiogenins from fish.

Q54WX4	AURK_DICDI	Probable serine/threonine-protein kinase aurK	18326585	Dictyostelium Aurora kinase has properties of both Aurora A and Aurora B kinases.

Q20924	SUN1_CAEEL	Sun domain-containing protein 1	14697201	The C. elegans hook protein, ZYG-12, mediates the essential attachment between the centrosome and nucleus.

O35543	HPGDS_RAT	Hematopoietic prostaglandin D synthase	9323136	Cloning and crystal structure of hematopoietic prostaglandin D synthase.

Q8NFZ5	TNIP2_HUMAN	TNFAIP3-interacting protein 2	12595760	An LKB1-interacting protein negatively regulates TNFalpha-induced NF- kappaB activation.

O13024	INCEA_XENLA	Inner centromere protein A	10996078	INCENP binds the Aurora-related kinase AIRK2 and is required to target it to chromosomes, the central spindle and cleavage furrow.

P55317	FOXA1_HUMAN	Hepatocyte nuclear factor 3-alpha	8652662	Molecular cloning of the forkhead transcription factor HNF-3 alpha from a human pulmonary adenocarcinoma cell line.

P20363	TBA3_ARATH	Tubulin alpha-3/alpha-5 chain	1498608	The small genome of Arabidopsis contains at least six expressed alpha-tubulin genes.

P57796	CABP4_HUMAN	Calcium-binding protein 4	16960802	Mutations in CABP4, the gene encoding the Ca2+-binding protein 4, cause autosomal recessive night blindness.

Q8C5S7	REC8_MOUSE	Meiotic recombination protein REC8 homolog	12759374	Temporally and spatially selective loss of Rec8 protein from meiotic chromosomes during mammalian meiosis.

Q8R0W6	NFIP1_MOUSE	NEDD4 family-interacting protein 1	17137798	Ndfip1 protein promotes the function of itch ubiquitin ligase to prevent T cell activation and T helper 2 cell-mediated inflammation.

P16050	LOX15_HUMAN	Arachidonate 15-lipoxygenase	3202857	Molecular cloning and primary structure of human 15-lipoxygenase.

P48727	GLC7B_CAEEL	Serine/threonine-protein phosphatase PP1-beta	11940606	The aurora kinase AIR-2 functions in the release of chromosome cohesion in Caenorhabditis elegans meiosis.

Q17850	PAK1_CAEEL	Serine/threonine-protein kinase pak-1	8824291	The Caenorhabditis elegans p21-activated kinase (CePAK) colocalizes with CeRac1 and CDC42Ce at hypodermal cell boundaries during embryo elongation.

O74879	NOL10_SCHPO	Ribosome biogenesis protein enp2 homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q14953	KI2S5_HUMAN	Killer cell immunoglobulin-like receptor 2DS5	8662091	Alternatively spliced forms of human killer inhibitory receptors.

Q9M353	CHX20_ARATH	Cation/H(+) antiporter 20	15347787	Expression patterns of a novel AtCHX gene family highlight potential roles in osmotic adjustment and K+ homeostasis in pollen development.

P33296	UBC6_YEAST	Ubiquitin-conjugating enzyme E2 6	16179953	Ubx2 links the Cdc48 complex to ER-associated protein degradation.

O74793	YOUB_SCHPO	Uncharacterized protein C26H8.11c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P30988	CALCR_HUMAN	Calcitonin receptor	15086532	Identification of a novel family of G protein-coupled receptor associated sorting proteins.

Q7TQC5	APTX_MOUSE	Aprataxin	16964241	The neurodegenerative disease protein aprataxin resolves abortive DNA ligation intermediates.

Q7KRY6	NHK1_DROME	Nucleosomal histone kinase 1	16230526	A histone code in meiosis: the histone kinase, NHK-1, is required for proper chromosomal architecture in Drosophila oocytes.

O74473	CDC11_SCHPO	Septation initiation network scaffold protein cdc11	11676915	S. pombe cdc11p, together with sid4p, provides an anchor for septation initiation network proteins on the spindle pole body.

Q92896	GSLG1_HUMAN	Golgi apparatus protein 1	8985126	Cloning and sequence analysis of the human MG160, a fibroblast growth factor and E-selectin binding membrane sialoglycoprotein of the Golgi apparatus.

O14582	TPPC2_HUMAN	Trafficking protein particle complex subunit 2	11805826	Functional organization of the yeast proteome by systematic analysis of protein complexes.

Q07807	PUF3_YEAST	mRNA-binding protein PUF3	12730603	Decapping and decay of messenger RNA occur in cytoplasmic processing bodies.

Q00839	HNRPU_HUMAN	Heterogeneous nuclear ribonucleoprotein U	7509195	hnRNP-U/SAF-A is encoded by two differentially polyadenylated mRNAs in human cells.

P21696	GPD1_SCHPO	Glycerol-3-phosphate dehydrogenase [NAD+] 1	8825100	Osmoregulation of fission yeast: cloning of two distinct genes encoding glycerol-3-phosphate dehydrogenase, one of which is responsible for osmotolerance for growth.

P0AGF6	THD2_ECOLI	Threonine dehydratase catabolic	3540965	Covalent structure of biodegradative threonine dehydratase of Escherichia coli: homology with other dehydratases.

P70056	FOXH1_XENLA	Forkhead box protein H1	14729957	Recognition of phosphorylated-Smad2-containing complexes by a novel Smad interaction motif.

Q99J79	DDB2_MOUSE	DNA damage-binding protein 2	15558025	Tumor-prone phenotype of the DDB2-deficient mice.

P40197	GPV_HUMAN	Platelet glycoprotein V	7690959	Human platelet glycoprotein V: characterization of the polypeptide and the related Ib-V-IX receptor system of adhesive, leucine-rich glycoproteins.

Q95ZQ4	AAPK2_CAEEL	5'-AMP-activated protein kinase catalytic subunit alpha-2	18408008	The Caenorhabditis elegans AMP-activated protein kinase AAK-2 is phosphorylated by LKB1 and is required for resistance to oxidative stress and for normal motility and foraging behavior.

P22694	KAPCB_HUMAN	cAMP-dependent protein kinase catalytic subunit beta	12420224	c-MYC activates protein kinase A (PKA) by direct transcriptional activation of the PKA catalytic subunit beta (PKA-CB) gene.

P70206	PLXA1_MOUSE	Plexin-A1	10520994	Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors.

O74883	RPC5_SCHPO	DNA-directed RNA polymerase III subunit rpc5	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O94633	DPM3_SCHPO	Dolichol-phosphate mannosyltransferase subunit 3	10835346	Human dolichol-phosphate-mannose synthase consists of three subunits, DPM1, DPM2 and DPM3.

Q94AH6	CUL1_ARATH	Cullin-1	11387208	SKP1-SnRK protein kinase interactions mediate proteasomal binding of a plant SCF ubiquitin ligase.

P39940	RSP5_YEAST	E3 ubiquitin-protein ligase RSP5	9931424	The PY-motif of Bul1 protein is essential for growth of Saccharomyces cerevisiae under various stress conditions.

Q9UTB1	YL87_SCHPO	HIG1 domain-containing protein C25B8.07c, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q16594	TAF9_HUMAN	Transcription initiation factor TFIID subunit 9	15899866	TAF9b (formerly TAF9L) is a bona fide TAF that has unique and overlapping roles with TAF9.

Q9VRP9	BRE1_DROME	E3 ubiquitin-protein ligase Bre1	15691768	Bre1 is required for Notch signaling and histone modification.

Q9W497	GR05A_DROME	Gustatory receptor for trehalose	11566105	Trehalose sensitivity in Drosophila correlates with mutations in and expression of the gustatory receptor gene Gr5a.

P55088	AQP4_MOUSE	Aquaporin-4	8660998	Gene structure, cDNA cloning, and expression of a mouse mercurial- insensitive water channel.

P53960	YNE0_YEAST	Putative alanyl-tRNA editing protein alaX	20010690	Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.

Q9UT34	YIQ9_SCHPO	Uncharacterized protein C824.09c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O74910	RAF1_SCHPO	Rik1-associated factor 1	16040243	Two novel proteins, dos1 and dos2, interact with rik1 to regulate heterochromatic RNA interference and histone modification.

Q9US55	GLU2A_SCHPO	Glucosidase 2 subunit alpha	9813085	The UDP-Glc:Glycoprotein glucosyltransferase is essential for Schizosaccharomyces pombe viability under conditions of extreme endoplasmic reticulum stress.

P35329	CD22_MOUSE	B-cell receptor CD22	10373493	Analysis of tyrosine phosphorylation-dependent interactions between stimulatory effector proteins and the B cell co-receptor CD22.

Q9XJ35	CLPR1_ARATH	ATP-dependent Clp protease proteolytic subunit-related protein 1, chloroplastic	11278690	Identification of a 350-kDa ClpP protease complex with 10 different Clp isoforms in chloroplasts of Arabidopsis thaliana.

P42746	UBC3_ARATH	Ubiquitin-conjugating enzyme E2 3	16339806	Genome analysis and functional characterization of the E2 and RING- type E3 ligase ubiquitination enzymes of Arabidopsis.

Q9P0S3	ORML1_HUMAN	ORM1-like protein 1	20182505	Orm family proteins mediate sphingolipid homeostasis.

Q54BD4	STATC_DICDI	Signal transducer and activator of transcription C	11336701	Tyrosine phosphorylation-independent nuclear translocation of a dictyostelium STAT in response to DIF signaling.

Q10758	K2C8_RAT	Keratin, type II cytoskeletal 8	15247274	Cloning and characterization of cytokeratins 8 and 19 in adult rat striated muscle. Interaction with the dystrophin glycoprotein complex.

Q96PC2	IP6K3_HUMAN	Inositol hexakisphosphate kinase 3	11502751	Identification and characterization of a novel inositol hexakisphosphate kinase.

Q16718	NDUA5_HUMAN	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5	9048877	A human cDNA encoding the homologue of NADH:ubiquinone oxidoreductase subunit B13.

Q80U87	UBP8_MOUSE	Ubiquitin carboxyl-terminal hydrolase 8	11500497	Cloning and characterization of mouse UBPy, a deubiquitinating enzyme that interacts with the ras guanine nucleotide exchange factor CDC25(Mm)/Ras-GRF1.

Q15617	OR8G1_HUMAN	Olfactory receptor 8G1	9119360	Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species.

Q43349	ROC2_ARATH	29 kDa ribonucleoprotein, chloroplastic	7894017	Three types of nuclear genes encoding chloroplast RNA-binding proteins (cp29, cp31 and cp33) are present in Arabidopsis thaliana: presence of cp31 in chloroplasts and its homologue in nuclei/cytoplasms.

P35326	SPR2A_HUMAN	Small proline-rich protein 2A	8325635	Molecular characterization and evolution of the SPRR family of keratinocyte differentiation markers encoding small proline-rich proteins.

Q60848	HELLS_MOUSE	Lymphocyte-specific helicase	14612388	Association of Lsh, a regulator of DNA methylation, with pericentromeric heterochromatin is dependent on intact heterochromatin.

P31749	AKT1_HUMAN	RAC-alpha serine/threonine-protein kinase	15718470	Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex.

P10588	NR2F6_HUMAN	Nuclear receptor subfamily 2 group F member 6	2905047	Identification of two novel members of erbA superfamily by molecular cloning: the gene products of the two are highly related to each other.

Q14739	LBR_HUMAN	Lamin-B receptor	12618959	Autosomal recessive HEM/Greenberg skeletal dysplasia is caused by 3 beta-hydroxysterol delta 14-reductase deficiency due to mutations in the lamin B receptor gene.

Q61241	TSSK1_MOUSE	Testis-specific serine/threonine-protein kinase 1	10781952	A novel member of the testis specific serine kinase family, tssk-3, expressed in the Leydig cells of sexually mature mice.

Q8VHJ7	PRGC2_MOUSE	Peroxisome proliferator-activated receptor gamma coactivator 1-beta	17618855	Transcriptional control of brown fat determination by PRDM16.

Q15811	ITSN1_HUMAN	Intersectin-1	9799604	Two isoforms of a human intersectin (ITSN) protein are produced by brain-specific alternative splicing in a stop codon.

P51156	RAB26_RAT	Ras-related protein Rab-26	10857477	Expression, characterization, and localization of Rab26, a low molecular weight GTP-binding protein, in the rat parotid gland.

P41005	MES1_SCHPO	Protein mes1	15791259	Fission yeast Mes1p ensures the onset of meiosis II by blocking degradation of cyclin Cdc13p.

P09228	CYTT_HUMAN	Cystatin-SA	3446578	Human cysteine-proteinase inhibitors: nucleotide sequence analysis of three members of the cystatin gene family.

P36157	MSA2_YEAST	Putative transcriptional activator MSA2	18160399	The SBF- and MBF-associated protein Msa1 is required for proper timing of G1-specific transcription in Saccharomyces cerevisiae.

P16975	SPRC_RAT	SPARC	2322281	Purification of a calcium binding protein (rat SPARC) from primary Sertoli cell-enriched culture medium.

Q05949	BUR2_YEAST	Protein BUR2	10454593	New yeast genes important for chromosome integrity and segregation identified by dosage effects on genome stability.

P12314	FCGR1_HUMAN	High affinity immunoglobulin gamma Fc receptor I	18322202	Filamin A stabilizes FcgammaRI surface expression and prevents its lysosomal routing.

P30519	HMOX2_HUMAN	Heme oxygenase 2	1575508	Human heme oxygenase-2: characterization and expression of a full- length cDNA and evidence suggesting that the two HO-2 transcripts may differ by choice of polyadenylation signal.

Q99624	S38A3_HUMAN	Sodium-coupled neutral amino acid transporter 3	10823827	Primary structure, genomic organization, and functional and electrogenic characteristics of human system N 1, a Na+- and H+- coupled glutamine transporter.

Q08952	OXR1_YEAST	Oxidation resistance protein 1	11114193	Functional genomics reveals a family of eukaryotic oxidation protection genes.

P49776	APH1_SCHPO	Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]	8554540	Cloning of the Schizosaccharomyces pombe gene encoding diadenosine 5',5''-P1,P4-tetraphosphate (Ap4A) asymmetrical hydrolase: sequence similarity with the histidine triad (HIT) protein family.

O14933	UB2L6_HUMAN	Ubiquitin/ISG15-conjugating enzyme E2 L6	16709802	NK lytic-associated molecule, involved in NK cytotoxic function, is an E3 ligase.

Q63666	VAMP1_RAT	Vesicle-associated membrane protein 1	9358054	Tissue-specific alternative RNA splicing of rat vesicle-associated membrane protein-1 (VAMP-1).

O43432	IF4G3_HUMAN	Eukaryotic translation initiation factor 4 gamma 3	9418880	A novel functional human eukaryotic translation initiation factor 4G.

Q27272	TAF9_DROME	Transcription initiation factor TFIID subunit 9	8598927	Structural similarity between TAFs and the heterotetrameric core of the histone octamer.

O75817	POP7_HUMAN	Ribonuclease P protein subunit p20	15096576	Mutual interactions between subunits of the human RNase MRP ribonucleoprotein complex.

P43119	PI2R_HUMAN	Prostacyclin receptor	7512962	Cloning and expression of a cDNA for the human prostanoid IP receptor.

Q9UJW3	DNM3L_HUMAN	DNA (cytosine-5)-methyltransferase 3-like	17713477	Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation.

P0A7V0	RS2_ECOLI	30S ribosomal protein S2	7023985	Primary structure of protein S2 from the Escherichia coli ribosome.

Q9FRV0	CHIC_SECCE	Basic endochitinase C	12092848	Antifungal activity of rye (Secale cereale) seed chitinases: the different binding manner of class I and class II chitinases to the fungal cell walls.

Q8GYD2	MND1_ARATH	Meiotic nuclear division protein 1 homolog	17937504	The interplay of RecA-related proteins and the MND1-HOP2 complex during meiosis in Arabidopsis thaliana.

O13759	CSX1_SCHPO	RNA-binding post-transcriptional regulator csx1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9USH7	PSY1_SCHPO	Syntaxin-like protein psy1	11739793	The Schizosaccharomyces pombe spo3+ gene is required for assembly of the forespore membrane and genetically interacts with psy1(+)-encoding syntaxin-like protein.

P33308	MED9_YEAST	Mediator of RNA polymerase II transcription subunit 9	8336709	CSE1 and CSE2, two new genes required for accurate mitotic chromosome segregation in Saccharomyces cerevisiae.

O60832	DKC1_HUMAN	H/ACA ribonucleoprotein complex subunit 4	16618814	Stepwise RNP assembly at the site of H/ACA RNA transcription in human cells.

Q9EQ51	V1R47_MOUSE	Vomeronasal type-1 receptor 47	11116090	Sequence diversity and genomic organization of vomeronasal receptor genes in the mouse.

Q9WVR7	PPM1F_RAT	Protein phosphatase 1F	10348902	Molecular cloning of Ca2+/Calmodulin-dependent protein kinase phosphatase.

P23908	ARGE_ECOLI	Acetylornithine deacetylase	1551850	Structural and biochemical characterization of the Escherichia coli argE gene product.

P38703	LAG1_YEAST	Sphingosine N-acyltransferase LAG1	8195187	Cloning and characterization of LAG1, a longevity-assurance gene in yeast.

P24158	PRTN3_HUMAN	Myeloblastin	2598267	Down-regulation of a serine protease, myeloblastin, causes growth arrest and differentiation of promyelocytic leukemia cells.

Q8H1Y0	ODPA2_ARATH	Pyruvate dehydrogenase E1 component subunit alpha-2, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q44457	FLIM_AGRT5	Flagellar motor switch protein FliM	9161425	The Agrobacterium tumefaciens motor gene, motA, is in a linked cluster with the flagellar switch protein genes, fliG, fliM and fliN.

Q9QZS6	HS3SB_MOUSE	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1	10520990	A novel role for 3-O-sulfated heparan sulfate in herpes simplex virus 1 entry.

P84095	RHOG_HUMAN	Rho-related GTP-binding protein RhoG	1620121	Growth-regulated expression of rhoG, a new member of the ras homolog gene family.

Q96KG9	NTKL_HUMAN	N-terminal kinase-like protein	18556652	Scyl1, mutated in a recessive form of spinocerebellar neurodegeneration, regulates COPI-mediated retrograde traffic.

O81445	CNBL1_ARATH	Calcineurin B-like protein 1	12897256	CBL1, a calcium sensor that differentially regulates salt, drought, and cold responses in Arabidopsis.

P61077	UB2D3_HUMAN	Ubiquitin-conjugating enzyme E2 D3	20061386	The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.

Q9GZV5	WWTR1_HUMAN	WW domain-containing transcription regulator protein 1	18568018	TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal.

P35465	PAK1_RAT	Serine/threonine-protein kinase PAK 1	10802735	Structure of Cdc42 bound to the GTPase binding domain of PAK.

P23760	PAX3_HUMAN	Paired box protein Pax-3	8447316	Mutations in the paired domain of the human PAX3 gene cause Klein- Waardenburg syndrome (WS-III) as well as Waardenburg syndrome type I (WS-I).

P15087	CBPE_RAT	Carboxypeptidase E	2784437	Rat preprocarboxypeptidase H. Cloning, characterization, and sequence of the cDNA and regulation of the mRNA by corticotropin-releasing factor.

P49747	COMP_HUMAN	Cartilage oligomeric matrix protein	16542502	Cartilage oligomeric matrix protein is involved in human limb development and in the pathogenesis of osteoarthritis.

Q8H1U5	APC2_ARATH	Anaphase-promoting complex subunit 2	14508008	The Arabidopsis anaphase-promoting complex or cyclosome: molecular and genetic characterization of the APC2 subunit.

P97479	MYO7A_MOUSE	Myosin-VIIa	9680294	Mutation analysis of the mouse myosin VIIA deafness gene.

Q10282	GBB_SCHPO	Guanine nucleotide-binding protein subunit beta	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q84JU4	IBR5_ARATH	Protein-tyrosine-phosphatase IBR5	14630970	IBR5, a dual-specificity phosphatase-like protein modulating auxin and abscisic acid responsiveness in Arabidopsis.

Q9BZD7	TMG3_HUMAN	Transmembrane gamma-carboxyglutamic acid protein 3	11171957	Identification of two novel transmembrane gamma-carboxyglutamic acid proteins expressed broadly in fetal and adult tissues.

Q46822	IDI_ECOLI	Isopentenyl-diphosphate Delta-isomerase	10419945	Escherichia coli open reading frame 696 is idi, a nonessential gene encoding isopentenyl diphosphate isomerase.

O08954	SNAI2_RAT	Zinc finger protein SNAI2	9182671	The zinc-finger protein Slug causes desmosome dissociation, an initial and necessary step for growth factor-induced epithelial- mesenchymal transition.

Q71RP1	HPSE_RAT	Heparanase	12077130	Characterization of heparanase from a rat parathyroid cell line.

Q23983	SNAP_DROME	Soluble NSF attachment protein	17151602	A systems biology analysis of the Drosophila phagosome.

O35819	KLF6_RAT	Krueppel-like factor 6	9689109	Zf9, a Kruppel-like transcription factor up-regulated in vivo during early hepatic fibrosis.

P38815	YPT35_YEAST	PX domain-containing protein YPT35	11557775	All phox homology (PX) domains from Saccharomyces cerevisiae specifically recognize phosphatidylinositol 3-phosphate.

O80397	M2K4_ARATH	Mitogen-activated protein kinase kinase 4	11875555	MAP kinase signalling cascade in Arabidopsis innate immunity.

P47047	MTR4_YEAST	ATP-dependent RNA helicase DOB1	8756671	A DEAD-box-family protein is required for nucleocytoplasmic transport of yeast mRNA.

Q9STP8	ACBP2_ARATH	Acyl-CoA-binding domain-containing protein 2	12650615	Membrane localization of Arabidopsis acyl-CoA binding protein ACBP2.

Q8CFD0	SFXN5_RAT	Sideroflexin-5	12150972	Identification and characterization of a novel mitochondrial tricarboxylate carrier.

Q03351	NTRK3_RAT	NT-3 growth factor receptor	8494647	Alternative forms of rat TrkC with different functional capabilities.

P53040	TAF6_YEAST	Transcription initiation factor TFIID subunit 6	9674426	A subset of TAF(II)s are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulation.

Q96MS0	ROBO3_HUMAN	Roundabout homolog 3	15105459	Mutations in a human ROBO gene disrupt hindbrain axon pathway crossing and morphogenesis.

P20069	MPPA_RAT	Mitochondrial-processing peptidase subunit alpha	2236012	The general mitochondrial matrix processing protease from rat liver: structural characterization of the catalytic subunit.

P62273	RS29_HUMAN	40S ribosomal protein S29	8781548	The S29 ribosomal protein increases tumor suppressor activity of K rev-1 gene on v-K ras-transformed NIH3T3 cells.

Q17446	PMK1_CAEEL	Mitogen-activated protein kinase pmk-1	12142542	A conserved p38 MAP kinase pathway in Caenorhabditis elegans innate immunity.

P54705	SNWA_DICDI	Protein snwA	11690648	Cyclophilins of a novel subfamily interact with SNW/SKIP coregulator in Dictyostelium discoideum and Schizosaccharomyces pombe.

P48361	ASK10_YEAST	Protein ASK10	8904339	Identification of ASK10 as a multicopy activator of Skn7p-dependent transcription of a HIS3 reporter gene.

P83319	FAR4_PENMO	FMRFamide-like neuropeptide FLP4	11959015	Seven novel FMRFamide-like neuropeptide sequences from the eyestalk of the giant tiger prawn Penaeus monodon.

P23443	KS6B1_HUMAN	Ribosomal protein S6 kinase beta-1	12150926	Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action.

P50462	CSRP3_MOUSE	Cysteine and glycine-rich protein 3	15665106	Attenuation of cardiac remodeling after myocardial infarction by muscle LIM protein-calcineurin signaling at the sarcomeric Z-disc.

Q9NP66	HM20A_HUMAN	High mobility group protein 20A	10773667	HMG20A and HMG20B map to human chromosomes 15q24 and 19p13.3 and constitute a distinct class of HMG-box genes with ubiquitous expression.

Q9ESJ7	IKBP1_MOUSE	Interleukin-1 receptor-associated kinase 1-binding protein 1	11096118	SIMPL is a tumor necrosis factor-specific regulator of nuclear factor-kappaB activity.

P07202	PERT_HUMAN	Thyroid peroxidase	2548579	Structure of the human thyroid peroxidase gene: comparison and relationship to the human myeloperoxidase gene.

O95994	AGR2_HUMAN	Anterior gradient protein 2 homolog	19359471	The protein disulfide isomerase AGR2 is essential for production of intestinal mucus.

Q8UVJ6	VANG2_DANRE	Vang-like protein 2	9007234	Mutations affecting development of the notochord in zebrafish.

P14618	KPYM_HUMAN	Pyruvate kinase isozymes M1/M2	18298799	Modulation of M2-type pyruvate kinase activity by the cytoplasmic PML tumor suppressor protein.

Q14517	FAT1_HUMAN	Protocadherin Fat 1	8586420	Molecular cloning and tissue expression of FAT, the human homologue of the Drosophila fat gene that is located on chromosome 4q34-q35 and encodes a putative adhesion molecule.

Q54K81	TALB_DICDI	Talin-B	10209124	A unique talin homologue with a villin headpiece-like domain is required for multicellular morphogenesis in Dictyostelium.

Q9Y237	PIN4_HUMAN	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4	17875217	The DNA binding parvulin Par17 is targeted to the mitochondrial matrix by a recently evolved prepeptide uniquely present in Hominidae.

Q03405	UPAR_HUMAN	Urokinase plasminogen activator surface receptor	1689240	Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis.

Q8LBP4	ALB3_ARATH	Inner membrane protein ALBINO3, chloroplastic	10636840	Chloroplast Oxa1p homolog albino3 is required for post-translational integration of the light harvesting chlorophyll-binding protein into thylakoid membranes.

Q07963	UBR2_YEAST	E3 ubiquitin-protein ligase UBR2	18070918	Genome-wide analysis identifies MYND-domain protein Mub1 as an essential factor for Rpn4 ubiquitylation.

P10815	CG23_SCHPO	G2/mitotic-specific cyclin cdc13	2908246	Cloning and sequencing of the cyclin-related cdc13+ gene and a cytological study of its role in fission yeast mitosis.

Q8TAF3	WDR48_HUMAN	WD repeat-containing protein 48	18082604	A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway.

O88833	CP4AA_MOUSE	Cytochrome P450 4A10	8031839	Deduced amino acid sequence of a murine cytochrome P-450 Cyp4a protein: developmental and hormonal regulation in liver and kidney.

P06732	KCRM_HUMAN	Creatine kinase M-type	3778496	Isolation and sequence analysis of a full-length cDNA for human M creatine kinase.

P30455	1A36_HUMAN	HLA class I histocompatibility antigen, A-36 alpha chain	1431115	Distinctive HLA-A,B antigens of black populations formed by interallelic conversion.

P53890	BNI5_YEAST	Bud neck protein 5	12215547	Bni5p, a septin-interacting protein, is required for normal septin function and cytokinesis in Saccharomyces cerevisiae.

Q9P6K9	DOHH_SCHPO	Deoxyhypusine hydroxylase	14767070	Mmd1p, a novel, conserved protein essential for normal mitochondrial morphology and distribution in the fission yeast Schizosaccharomyces pombe.

Q96SF2	TCPQM_HUMAN	Putative T-complex protein 1 subunit theta-like 2	10585773	Identification of a putative regulatory subunit of a calcium- activated potassium channel in the dup(3q) syndrome region and a related sequence on 22q11.2.

Q9FLU1	BIN4_ARATH	DNA-binding protein BIN4	18055605	BIN4, a novel component of the plant DNA topoisomerase VI complex, is required for endoreduplication in Arabidopsis.

Q06683	IRC3_YEAST	Putative ATP-dependent helicase IRC3	14562095	Global analysis of protein localization in budding yeast.

Q5XJA3	PRRC1_DANRE	Protein PRRC1	18342848	Misty somites, a maternal effect gene identified by transposon- mediated insertional mutagenesis in zebrafish that is essential for the somite boundary maintenance.

Q9Y6J0	CABIN_HUMAN	Calcineurin-binding protein cabin-1	9655484	Cabin 1, a negative regulator for calcineurin signaling in T lymphocytes.

Q8C6P8	ZFP57_MOUSE	Zinc finger protein 57	18854139	A maternal-zygotic effect gene, Zfp57, maintains both maternal and paternal imprints.

P40990	MSS2_YEAST	Protein MSS2, mitochondrial	11604502	Peripheral mitochondrial inner membrane protein, Mss2p, required for export of the mitochondrially coded Cox2p C tail in Saccharomyces cerevisiae.

Q5JQC9	AKAP4_HUMAN	A-kinase anchor protein 4	9822690	An X-linked gene encodes a major human sperm fibrous sheath protein, hAKAP82. Genomic organization, protein kinase A-RII binding, and distribution of the precursor in the sperm tail.

Q17868	CKS1_CAEEL	Cyclin-dependent kinases regulatory subunit	16343905	The conserved kinases CDK-1, GSK-3, KIN-19, and MBK-2 promote OMA-1 destruction to regulate the oocyte-to-embryo transition in C. elegans.

O88879	APAF_MOUSE	Apoptotic protease-activating factor 1	15271982	Nucling recruits Apaf-1/pro-caspase-9 complex for the induction of stress-induced apoptosis.

Q8K4R8	NPT2C_RAT	Sodium-dependent phosphate transport protein 2C	11880379	Growth-related renal type II Na/Pi cotransporter.

O76460	RAD54_DROME	DNA repair and recombination protein RAD54-like	15105430	A conserved N-terminal motif in Rad54 is important for chromatin remodeling and homologous strand pairing.

Q8RYC6	IAA32_ARATH	Auxin-responsive protein IAA32	12036262	Genetics of Aux/IAA and ARF action in plant growth and development.

Q5TAX3	TUT4_HUMAN	Terminal uridylyltransferase 4	19703396	TUT4 in concert with Lin28 suppresses MicroRNA biogenesis through pre-microRNA uridylation.

Q61133	GSTT2_MOUSE	Glutathione S-transferase theta-2	8761485	The distribution of theta-class glutathione S-transferases in the liver and lung of mouse, rat and human.

Q9SRS9	CHIP_ARATH	E3 ubiquitin-protein ligase CHIP	20028838	Heat shock protein cognate 70-4 and an E3 ubiquitin ligase, CHIP, mediate plastid-destined precursor degradation through the ubiquitin- 26S proteasome system in Arabidopsis.

P15822	ZEP1_HUMAN	Zinc finger protein 40	2106471	A DNA-binding protein containing two widely separated zinc finger motifs that recognize the same DNA sequence.

P43063	CDK1_CANAL	Cell division control protein 28	8654974	Candida albicans CDK1 and CYB1: cDNA homologues of the cdc2/CDC28 and cdc13/CLB1/CLB2 cell cycle control genes.

Q13065	GAGE1_HUMAN	G antigen 1	7544395	A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma.

P28307	CSGA_ECOLI	Major curlin subunit	8817489	Expression of two csg operons is required for production of fibronectin- and congo red-binding curli polymers in Escherichia coli K-12.

P38773	DOG2_YEAST	2-deoxyglucose-6-phosphate phosphatase 2	8553694	DOGR1 and DOGR2: two genes from Saccharomyces cerevisiae that confer 2-deoxyglucose resistance when overexpressed.

Q9M2P7	PAP9_ARATH	Probable plastid-lipid-associated protein 9, chloroplastic	16461379	Protein profiling of plastoglobules in chloroplasts and chromoplasts. A surprising site for differential accumulation of metabolic enzymes.

P40099	FTHC_YEAST	5-formyltetrahydrofolate cyclo-ligase	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P33076	C2TA_HUMAN	MHC class II transactivator	17493635	The zinc finger proteins ZXDA and ZXDC form a complex that binds CIITA and regulates MHC II gene transcription.

P81800	PPB1_PREIN	Alkaline phosphatase	9654126	Purification and characterization of alkaline phosphatase containing phosphotyrosyl phosphatase activity from the bacterium Prevotella intermedia.

Q86L04	TRAP1_DICDI	TNF receptor-associated protein 1 homolog, mitochondrial	15652354	Involvement of the TRAP-1 homologue, Dd-TRAP1, in spore differentiation during Dictyostelium development.

P0A6T5	GCH1_ECOLI	GTP cyclohydrolase 1	7663943	Atomic structure of GTP cyclohydrolase I.

P26659	RAD15_SCHPO	DNA repair helicase rad15	1534406	The Schizosaccharomyces pombe rhp3+ gene required for DNA repair and cell viability is functionally interchangeable with the RAD3 gene of Saccharomyces cerevisiae.

Q55GF9	ICPA_DICDI	Inner centromere protein A	16339076	Contractile ring-independent localization of DdINCENP, a protein important for spindle stability and cytokinesis.

Q920A6	RISC_RAT	Retinoid-inducible serine carboxypeptidase	11447226	Cloning of a novel retinoid-inducible serine carboxypeptidase from vascular smooth muscle cells.

Q86VW1	S22AG_HUMAN	Solute carrier family 22 member 16	12089149	Molecular identification of a novel carnitine transporter specific to human testis. Insights into the mechanism of carnitine recognition.

Q56YN3	NADK1_ARATH	NAD(H) kinase 1	15247403	Cloning and characterization of two NAD kinases from Arabidopsis. Identification of a calmodulin binding isoform.

Q8T4F7	ENA_DROME	Protein enabled	10220404	Identification of profilin and src homology 3 domains as binding partners for Drosophila enabled.

P12931	SRC_HUMAN	Proto-oncogene tyrosine-protein kinase Src	9924018	Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes.

Q96EN8	MOCOS_HUMAN	Molybdenum cofactor sulfurase	11302742	Mutation of human molybdenum cofactor sulfurase gene is responsible to classical xanthinuria type II.

P12270	TPR_HUMAN	Nucleoprotein TPR	7798308	Tpr, a large coiled coil protein whose amino terminus is involved in activation of oncogenic kinases, is localized to the cytoplasmic surface of the nuclear pore complex.

Q04179	URH1_YEAST	Uridine nucleosidase	14562095	Global analysis of protein localization in budding yeast.

P35584	FOXA3_MOUSE	Hepatocyte nuclear factor 3-gamma	11546810	Foxa3 (hepatocyte nuclear factor 3gamma) is required for the regulation of hepatic GLUT2 expression and the maintenance of glucose homeostasis during a prolonged fast.

Q800K6	TOB1A_XENLA	DNA topoisomerase 2-binding protein 1-A	12730133	A novel ring-like complex of Xenopus proteins essential for the initiation of DNA replication.

Q9H1B7	EAP1_HUMAN	Enhanced at puberty protein 1	11095982	Characterization of C14orf4, a novel intronless human gene containing a polyglutamine repeat, mapped to the ARVD1 critical region.

Q9XTT8	PP4C2_CAEEL	Serine/threonine-protein phosphatase 4 catalytic subunit 2	11896188	Protein phosphatase 4 is required for centrosome maturation in mitosis and sperm meiosis in C. elegans.

Q9UPV9	TRAK1_HUMAN	Trafficking kinesin-binding protein 1	18675823	Hypertonia-associated protein Trak1 is a novel regulator of endosome- to-lysosome trafficking.

Q07231	ZSC21_MOUSE	Zinc finger and SCAN domain-containing protein 21	8625807	Granule cell specification in the developing mouse brain as defined by expression of the zinc finger transcription factor RU49.

Q03124	RSC9_YEAST	Chromatin structure-remodeling complex subunit RSC9	11931764	The genome-wide localization of Rsc9, a component of the RSC chromatin-remodeling complex, changes in response to stress.

O00165	HAX1_HUMAN	HCLS1-associated protein X-1	9058808	HAX-1, a novel intracellular protein, localized on mitochondria, directly associates with HS1, a substrate of Src family tyrosine kinases.

P70550	RAB8B_RAT	Ras-related protein Rab-8B	11278749	Rab8b and its interacting partner TRIP8b are involved in regulated secretion in AtT20 cells.

P06174	HEM4_YEAST	Uroporphyrinogen-III synthase	7597845	Isolation of the gene HEM4 encoding uroporphyrinogen III synthase in Saccharomyces cerevisiae.

P50085	PHB2_YEAST	Prohibitin-2	10835343	Prohibitins act as a membrane-bound chaperone for the stabilization of mitochondrial proteins.

Q16610	ECM1_HUMAN	Extracellular matrix protein 1	11292659	Extracellular matrix protein 1 (ECM1) has angiogenic properties and is expressed by breast tumor cells.

Q9V751	ATTB_DROME	Attacin-B	10767526	Two attacin antibacterial genes of Drosophila melanogaster.

O75822	EIF3J_HUMAN	Eukaryotic translation initiation factor 3 subunit J	14688252	The j-subunit of human translation initiation factor eIF3 is required for the stable binding of eIF3 and its subcomplexes to 40 S ribosomal subunits in vitro.

O14842	FFAR1_HUMAN	Free fatty acid receptor 1	12496284	The orphan G protein-coupled receptor GPR40 is activated by medium and long-chain fatty acids.

P38629	RFC3_YEAST	Replication factor C subunit 3	8302859	Molecular cloning and expression of the Saccharomyces cerevisiae RFC3 gene, an essential component of replication factor C.

Q8IX03	KIBRA_HUMAN	Protein KIBRA	20159598	Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded.

P85125	PTRF_RAT	Polymerase I and transcript release factor	16236245	Identification of a major protein on the cytosolic face of caveolae.

O77229	CATA_DICDI	Catalase-A	11782526	Methanol and acriflavine resistance in Dictyostelium are caused by loss of catalase.

P40120	OPGD_ECOLI	Glucans biosynthesis protein D	17218314	Export pathway selectivity of Escherichia coli twin arginine translocation signal peptides.

P35713	SOX18_HUMAN	Transcription factor SOX-18	12740761	Mutations in the transcription factor gene SOX18 underlie recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia.

Q99962	SH3G2_HUMAN	Endophilin-A1	9169142	A novel SH3-containing human gene family preferentially expressed in the central nervous system.

Q9NQ90	ANO2_HUMAN	Anoctamin-2	19474308	TMEM16B, a novel protein with calcium-dependent chloride channel activity, associates with a presynaptic protein complex in photoreceptor terminals.

O43435	TBX1_HUMAN	T-box transcription factor TBX1	14585638	Role of TBX1 in human del22q11.2 syndrome.

P39723	SPC72_YEAST	Spindle pole component SPC72	17967947	The yeast centrosome translates the positional information of the anaphase spindle into a cell cycle signal.

P53675	CLH2_HUMAN	Clathrin heavy chain 2	8844170	Cloning and characterization of a novel human clathrin heavy chain gene (CLTCL).

Q1MTN3	PIC1_SCHPO	Inner centromere protein-related protein pic1	16199877	Suppressors of Bir1p (Survivin) identify roles for the chromosomal passenger protein Pic1p (INCENP) and the replication initiation factor Psf2p in chromosome segregation.

Q14512	FGFP1_HUMAN	Fibroblast growth factor-binding protein 1	1885605	Characterization and molecular cloning of a putative binding protein for heparin-binding growth factors.

O14662	STX16_HUMAN	Syntaxin-16	9464276	Molecular cloning and localization of human syntaxin 16, a member of the syntaxin family of SNARE proteins.

P32564	SCM4_YEAST	Protein SCM4	1465103	SCM4, a gene that suppresses mutant cdc4 function in budding yeast.

P21461	SINA_DROME	E3 ubiquitin-protein ligase sina	11032805	A role for Ebi in neuronal cell cycle control.

P49597	P2C56_ARATH	Protein phosphatase 2C 56	19769575	Closely related receptor complexes differ in their ABA selectivity and sensitivity.

Q08202	OPI10_YEAST	Protein OPI10	16582425	Genomic analysis of the Opi- phenotype.

Q9ZUX7	IPT2_ARATH	tRNA dimethylallyltransferase 2	11999372	Identification of a tRNA isopentenyltransferase gene from Arabidopsis thaliana.

O95822	DCMC_HUMAN	Malonyl-CoA decarboxylase, mitochondrial	10455107	MCD encodes peroxisomal and cytoplasmic forms of malonyl-CoA decarboxylase and is mutated in malonyl-CoA decarboxylase deficiency.

O13826	RFP1_SCHPO	E3 ubiquitin-protein ligase complex slx8-rfp subunit rfp1	17762864	Conserved function of RNF4 family proteins in eukaryotes: targeting a ubiquitin ligase to SUMOylated proteins.

Q8L940	PDX13_ARATH	Pyridoxal biosynthesis protein PDX1.3	16766694	Analysis of the Arabidopsis rsr4-1/pdx1-3 mutant reveals the critical function of the PDX1 protein family in metabolism, development, and vitamin B6 biosynthesis.

Q02554	CUS1_YEAST	Protein CUS1	8566755	CUS1, a suppressor of cold-sensitive U2 snRNA mutations, is a novel yeast splicing factor homologous to human SAP 145.

P93024	ARFE_ARATH	Auxin response factor 5	9342315	Protein-protein interactions among the Aux/IAA proteins.

P32245	MC4R_HUMAN	Melanocortin receptor 4	8392067	Molecular cloning, expression, and gene localization of a fourth melanocortin receptor.

Q9M6E9	AGGL_ABRPR	Agglutinin-1	10636890	Primary structure and function analysis of the Abrus precatorius agglutinin A chain by site-directed mutagenesis. Pro(199) Of amphiphilic alpha-helix H impairs protein synthesis inhibitory activity.

P29476	NOS1_RAT	Nitric oxide synthase, brain	11086993	Dexras1: a G protein specifically coupled to neuronal nitric oxide synthase via CAPON.

P15104	GLNA_HUMAN	Glutamine synthetase	18662667	Glutamine synthetase is essential for proliferation of fetal skin fibroblasts.

P36152	DRE2_YEAST	Fe-S cluster assembly protein DRE2	18625724	Dre2, a conserved eukaryotic Fe/S cluster protein, functions in cytosolic Fe/S protein biogenesis.

P30664	MCM4B_XENLA	DNA replication licensing factor mcm4-B	9851868	Evidence for different MCM subcomplexes with differential binding to chromatin in Xenopus.

P04637	P53_HUMAN	Cellular tumor antigen p53	20096447	USP10 regulates p53 localization and stability by deubiquitinating p53.

Q9W0V1	PDPK1_DROME	3-phosphoinositide-dependent protein kinase 1	11752451	PDK1 regulates growth through Akt and S6K in Drosophila.

O95363	SYFM_HUMAN	Phenylalanyl-tRNA synthetase, mitochondrial	10329163	Expression and characterization of a human mitochondrial phenylalanyl-tRNA synthetase.

Q92794	MYST3_HUMAN	Histone acetyltransferase MYST3	8782817	The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein.

Q9UBJ2	ABCD2_HUMAN	ATP-binding cassette sub-family D member 2	10329405	Full length cDNA cloning, promoter sequence, and genomic organization of the human adrenoleukodystrophy related (ALDR) gene functionally redundant to the gene responsible for X-linked adrenoleukodystrophy.

Q09926	PCR1_SCHPO	Transcription factor pcr1	7958849	A heteromeric protein that binds to a meiotic homologous recombination hot spot: correlation of binding and hot spot activity.

P32526	KAR9_YEAST	Karyogamy protein KAR9	9442113	Kar9p is a novel cortical protein required for cytoplasmic microtubule orientation in yeast.

Q9FRV1	CHIA_SECCE	Basic endochitinase A	12092848	Antifungal activity of rye (Secale cereale) seed chitinases: the different binding manner of class I and class II chitinases to the fungal cell walls.

P20338	RAB4A_HUMAN	Ras-related protein Rab-4A	15907487	High resolution crystal structures of human Rab4a in its active and inactive conformations.

Q60854	SPB6_MOUSE	Serpin B6	7608171	Gene structure, chromosomal localization, and expression of the murine homologue of human proteinase inhibitor 6 (PI-6) suggests divergence of PI-6 from the ovalbumin serpins.

Q768S4	RPH3L_MOUSE	Rab effector Noc2	15159548	Noc2 is essential in normal regulation of exocytosis in endocrine and exocrine cells.

P32501	EI2BE_YEAST	Translation initiation factor eIF-2B subunit epsilon	10805739	Identification of domains and residues within the epsilon subunit of eukaryotic translation initiation factor 2B (eIF2Bepsilon) required for guanine nucleotide exchange reveals a novel activation function promoted by eIF2B complex formation.

Q12277	RRP42_YEAST	Exosome complex component RRP42	9390555	The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases.

Q13206	DDX10_HUMAN	Probable ATP-dependent RNA helicase DDX10	8660968	A human gene (DDX10) encoding a putative DEAD-box RNA helicase at 11q22-q23.

Q96T53	MBOA4_HUMAN	Ghrelin O-acyltransferase	18443287	Ghrelin octanoylation mediated by an orphan lipid transferase.

P32349	RPC3_YEAST	DNA-directed RNA polymerase III subunit RPC3	1406632	RPC82 encodes the highly conserved, third-largest subunit of RNA polymerase C (III) from Saccharomyces cerevisiae.

O00086	IMDH3_CANAL	Probable inosine-5'-monophosphate dehydrogenase	9079920	Overexpression of a cloned IMP dehydrogenase gene of Candida albicans confers resistance to the specific inhibitor mycophenolic acid.

Q09232	ORAI_CAEEL	Protein orai	17218360	CRAC channel activity in C. elegans is mediated by Orai1 and STIM1 homologues and is essential for ovulation and fertility.

Q9SAI4	NIP61_ARATH	Aquaporin NIP6-1	16363796	Distinct transport selectivity of two structural subclasses of the nodulin-like intrinsic protein family of plant aquaglyceroporin channels.

Q06224	YSH1_YEAST	Endoribonuclease YSH1	12626716	Functional dissection of the zinc finger and flanking domains of the Yth1 cleavage/polyadenylation factor.

P27434	RODZ_ECOLI	Cytoskeleton protein rodZ	19008860	Determination of bacterial rod shape by a novel cytoskeletal membrane protein.

Q8MSX1	ENC_DROME	Protein encore	11044391	Encore is a member of a novel family of proteins and affects multiple processes in Drosophila oogenesis.

Q5S007	LRRK2_HUMAN	Leucine-rich repeat serine/threonine-protein kinase 2	16269541	Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity.

O60870	KIN17_HUMAN	DNA/RNA-binding protein KIN17	12754299	Participation of kin17 protein in replication factories and in other DNA transactions mediated by high molecular weight nuclear complexes.

Q8IU60	DCP2_HUMAN	mRNA-decapping enzyme 2	15231747	A protein interaction framework for human mRNA degradation.

Q7M370	AAAD_RABIT	Arylacetamide deacetylase	15152005	Appropriate function of 11beta-hydroxysteroid dehydrogenase type 1 in the endoplasmic reticulum lumen is dependent on its N-terminal region sharing similar topological determinants with 50-kDa esterase.

P83146	ASL1_BACSE	Acharan sulfate lyase 1	11322884	Purification and characterization of acharan sulfate lyases, two novel heparinases, from Bacteroides stercoris HJ-15.

O80915	PR1B4_ARATH	PRA1 family protein B4	18583532	The PRA1 gene family in Arabidopsis.

Q96T23	RSF1_HUMAN	Remodeling and spacing factor 1	12972596	Functional analysis of the subunits of the chromatin assembly factor RSF.

Q9M5P2	SCAM3_ARATH	Secretory carrier-associated membrane protein 3	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q9W0T1	NU301_DROME	Nucleosome-remodeling factor subunit NURF301	12502740	Biological functions of the ISWI chromatin remodeling complex NURF.

Q9ASS6	CP20B_ARATH	Peptidyl-prolyl cis-trans isomerase CYP20-2, chloroplastic	15322131	New functions of the thylakoid membrane proteome of Arabidopsis thaliana revealed by a simple, fast, and versatile fractionation strategy.

O14556	G3PT_HUMAN	Glyceraldehyde-3-phosphate dehydrogenase, testis-specific	16820410	Novel function of beta-arrestin2 in the nucleus of mature spermatozoa.

P04792	HSPB1_HUMAN	Heat shock protein beta-1	16548883	Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection.

O88310	ITL1A_MOUSE	Intelectin-1a	17420014	Nippostrongylus brasiliensis: identification of intelectin-1 and -2 as Stat6-dependent genes expressed in lung and intestine during infection.

P35177	SPT7_YEAST	Transcriptional activator SPT7	9674426	A subset of TAF(II)s are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulation.

Q9VM08	GR28B_DROME	Putative gustatory receptor 28b	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

O94992	HEXI1_HUMAN	Protein HEXIM1	15941832	HEXIM1 forms a transcriptionally abortive complex with glucocorticoid receptor without involving 7SK RNA and positive transcription elongation factor b.

Q9SN86	MDHP_ARATH	Malate dehydrogenase, chloroplastic	12766230	Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.

P20095	PRP2_YEAST	Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2	1534753	The purified yeast pre-mRNA splicing factor PRP2 is an RNA-dependent NTPase.

Q9UTP5	MU162_SCHPO	Meiotically up-regulated gene 162 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P25963	IKBA_HUMAN	NF-kappa-B inhibitor alpha	20347421	Priming and extending: a UbcH5/Cdc34 E2 handoff mechanism for polyubiquitination on a SCF substrate.

Q90ZH9	S17AB_XENLA	Transcription factor Sox-17-alpha-B	15302595	Repression of nodal expression by maternal B1-type SOXs regulates germ layer formation in Xenopus and zebrafish.

Q12218	TIR4_YEAST	Cell wall protein TIR4	10383953	Amino acid residues in the omega-minus region participate in cellular localization of yeast glycosylphosphatidylinositol-attached proteins.

Q15058	KIF14_HUMAN	Kinesin-like protein KIF14	16820410	Novel function of beta-arrestin2 in the nucleus of mature spermatozoa.

Q9Y267	S22AE_HUMAN	Solute carrier family 22 member 14	10072596	Molecular cloning, mapping, and characterization of two novel human genes, ORCTL3 and ORCTL4, bearing homology to organic-cation transporters.

P50548	ERF_HUMAN	ETS domain-containing transcription factor ERF	7588608	ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation.

Q8GZ17	COBL7_ARATH	COBRA-like protein 7	12805588	Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis.

P84075	HPCA_MOUSE	Neuron-specific calcium-binding protein hippocalcin	9931466	Genomic structure and chromosomal mapping of the human and mouse hippocalcin genes.

Q99592	ZN238_HUMAN	Zinc finger protein 238	9756912	RP58 associates with condensed chromatin and mediates a sequence- specific transcriptional repression.

P25042	ROX1_YEAST	Repressor ROX1	8413209	The Rox1 repressor of the Saccharomyces cerevisiae hypoxic genes is a specific DNA-binding protein with a high-mobility-group motif.

P92973	CCA1_ARATH	Protein CCA1	14978263	CK2 phosphorylation of CCA1 is necessary for its circadian oscillator function in Arabidopsis.

P24752	THIL_HUMAN	Acetyl-CoA acetyltransferase, mitochondrial	1979337	Molecular cloning and sequence of the complementary DNA encoding human mitochondrial acetoacetyl-coenzyme A thiolase and study of the variant enzymes in cultured fibroblasts from patients with 3- ketothiolase deficiency.

P87314	HIR1_SCHPO	Protein hir1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P22888	LSHR_HUMAN	Lutropin-choriogonadotropic hormone receptor	9626653	A homozygous mutation in the luteinizing hormone receptor causes partial Leydig cell hypoplasia: correlation between receptor activity and phenotype.

Q16613	SNAT_HUMAN	Serotonin N-acetyltransferase	8661026	The human serotonin N-acetyltransferase (EC 2.3.1.87) gene (AANAT): structure, chromosomal localization, and tissue expression.

O75936	BODG_HUMAN	Gamma-butyrobetaine dioxygenase	9753662	Carnitine biosynthesis: identification of the cDNA encoding human gamma-butyrobetaine hydroxylase.

P28817	HIBCH_YEAST	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial	12697341	The biochemistry of peroxisomal beta-oxidation in the yeast Saccharomyces cerevisiae.

O60609	GFRA3_HUMAN	GDNF family receptor alpha-3	9576965	GFRalpha3 is an orphan member of the GDNF/neurturin/persephin receptor family.

Q04472	MGR3_YEAST	Mitochondrial inner membrane i-AAA protease supercomplex subunit MGR3	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

O15150	MYT2_HUMAN	Replication initiation-like protein	9790734	A secreted DNA-binding protein that is translated through an internal ribosome entry site (IRES) and distributed in a discrete pattern in the central nervous system.

Q6WKZ7	NOSTN_MOUSE	Nostrin	16171775	Mouse disabled 2-interacting protein 2 functions as a transcriptional repressor through direct binding onto its own promoter.

P38737	ECM29_YEAST	Proteasome component ECM29	14562095	Global analysis of protein localization in budding yeast.

O93235	CIRBA_XENLA	Cold-inducible RNA-binding protein A	11018519	Maternal cold inducible RNA binding protein is required for embryonic kidney formation in Xenopus laevis.

P18612	KIN1_ARATH	Stress-induced protein KIN1	2151730	Cloning and characterization of a cold- and ABA-inducible Arabidopsis gene.

P19339	SXL_DROME	Protein sex-lethal	12444081	Biochemical function of female-lethal (2)D/Wilms' tumor suppressor-1- associated proteins in alternative pre-mRNA splicing.

Q9WTW8	S23A2_RAT	Solute carrier family 23 member 2	10331392	A family of mammalian Na+-dependent L-ascorbic acid transporters.

O75525	KHDR3_HUMAN	KH domain-containing, RNA-binding, signal transduction-associated protein 3	10332027	T-STAR/ETOILE: a novel relative of SAM68 that interacts with an RNA- binding protein implicated in spermatogenesis.

Q13188	STK3_HUMAN	Serine/threonine-protein kinase 3	8816758	Newly identified stress-responsive protein kinases, Krs-1 and Krs- 2.

Q15276	RABE1_HUMAN	Rab GTPase-binding effector protein 1	12505986	Divalent interaction of the GGAs with the Rabaptin-5-Rabex-5 complex.

Q04500	UTP14_YEAST	U3 small nucleolar RNA-associated protein 14	12068309	A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis.

Q05610	DON1_YEAST	Donuts protein 1	11742972	Prospore membrane formation linked to the leading edge protein (LEP) coat assembly.

P43699	NKX21_HUMAN	Homeobox protein Nkx-2.1	19010321	TAZ is a coactivator for Pax8 and TTF-1, two transcription factors involved in thyroid differentiation.

Q15910	EZH2_HUMAN	Histone-lysine N-methyltransferase EZH2	16179254	The human tumor antigen PRAME is a dominant repressor of retinoic acid receptor signaling.

P40003	VAB2_YEAST	Protein VAB2	14562095	Global analysis of protein localization in budding yeast.

P40078	NSA2_YEAST	Ribosome biogenesis protein NSA2	17443350	In vivo functional characterization of the Saccharomyces cerevisiae 60S biogenesis GTPase Nog1.

Q9UBP0	SPAST_HUMAN	Spastin	15716377	Linking axonal degeneration to microtubule remodeling by Spastin- mediated microtubule severing.

O75528	TADA3_HUMAN	Transcriptional adapter 3	9674425	Histone-like TAFs within the PCAF histone acetylase complex.

Q66GT5	PTPM1_MOUSE	Protein-tyrosine phosphatase mitochondrial 1	15247229	A PTEN-like phosphatase with a novel substrate specificity.

P15170	ERF3A_HUMAN	Eukaryotic peptide chain release factor GTP-binding subunit ERF3A	2511002	A human homologue of the yeast GST1 gene codes for a GTP-binding protein and is expressed in a proliferation-dependent manner in mammalian cells.

O14161	CWC21_SCHPO	Pre-mRNA-splicing factor cwc21	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9QXZ9	OPN4_MOUSE	Melanopsin	12808468	Melanopsin and rod-cone photoreceptive systems account for all major accessory visual functions in mice.

Q9NS91	RAD18_HUMAN	E3 ubiquitin-protein ligase RAD18	10908344	The human RAD18 gene product interacts with HHR6A and HHR6B.

Q13772	NCOA4_HUMAN	Nuclear receptor coactivator 4	8643607	Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells.

Q9UWF6	PLB1_CANAL	Lysophospholipase 1	9748287	Cloning and disruption of caPLB1, a phospholipase B gene involved in the pathogenicity of Candida albicans.

Q8VGC3	CACB2_RAT	Voltage-dependent L-type calcium channel subunit beta-2	1370480	Cloning and expression of a cardiac/brain beta subunit of the L-type calcium channel.

Q02410	APBA1_HUMAN	Amyloid beta A4 precursor protein-binding family A member 1	8887653	The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein.

P35998	PRS7_HUMAN	26S protease regulatory subunit 7	9295362	HEC binds to the seventh regulatory subunit of the 26 S proteasome and modulates the proteolysis of mitotic cyclins.

Q9SB92	WUS_ARATH	Protein WUSCHEL	16461579	Analysis of the transcription factor WUSCHEL and its functional homologue in Antirrhinum reveals a potential mechanism for their roles in meristem maintenance.

Q60520	SIN3A_MOUSE	Paired amphipathic helix protein Sin3a	8521822	Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation.

Q9USP1	ELP4_SCHPO	Elongator complex protein 4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q93454	NPP17_CAEEL	Nucleoporin-17	12937276	Caenorhabditis elegans nucleoporins Nup93 and Nup205 determine the limit of nuclear pore complex size exclusion in vivo.

P58462	FOXP1_MOUSE	Forkhead box protein P1	11358962	Characterization of a new subfamily of winged-helix/forkhead (Fox) genes that are expressed in the lung and act as transcriptional repressors.

Q9Z179	SHCBP_MOUSE	SHC SH2 domain-binding protein 1	10086341	Cloning and characterization of mPAL, a novel Shc SH2 domain-binding protein expressed in proliferating cells.

Q9DBL9	ABHD5_MOUSE	1-acylglycerol-3-phosphate O-acyltransferase ABHD5	15292255	Perilipin A mediates the reversible binding of CGI-58 to lipid droplets in 3T3-L1 adipocytes.

P35550	FBRL_MOUSE	rRNA 2'-O-methyltransferase fibrillarin	8218401	Molecular cloning and sequence analysis of U3 snoRNA-associated mouse fibrillarin.

Q9HDT8	YJ51_SCHPO	UPF0612 protein P20C8.01c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q09191	RPAB1_SCHPO	DNA-directed RNA polymerases I, II, and III subunit RPABC1	9077438	Molecular assembly of RNA polymerase II from the fission yeast Schizosaccharomyces pombe: subunit-subunit contact network involving Rpb5.

P63345	ARC_MYCTU	Proteasome-associated ATPase	18832610	Ubiquitin-like protein involved in the proteasome pathway of Mycobacterium tuberculosis.

O75845	SC5D_HUMAN	Lathosterol oxidase	8976377	Molecular cloning and mapping of a human cDNA(SC5DL) encoding a protein homologous to fungal sterol-C5-desaturase.

O75603	GCM2_HUMAN	Chorion-specific transcription factor GCMb	9928992	Isolation and expression analysis of a novel human homologue of the Drosophila glial cells missing (gcm) gene.

Q50HP3	SPC19_SCHPO	DASH complex subunit spc19	16079914	Molecular analysis of kinetochore architecture in fission yeast.

P87377	VEGTA_XENLA	T-box protein VegT-A	17541407	POU-V factors antagonize maternal VegT activity and beta-Catenin signaling in Xenopus embryos.

Q15726	KISS1_HUMAN	Metastasis-suppressor KiSS-1	9192814	Suppression of metastasis in human breast carcinoma MDA-MB-435 cells after transfection with the metastasis suppressor gene, KiSS-1.

B7ZRU9	EVI1A_XENLA	MDS1 and EVI1 complex locus protein EVI1-A	15905132	Evi-1 expression in Xenopus.

Q8W1S1	DGDG2_ARATH	Digalactosyldiacylglycerol synthase 2, chloroplastic	11696551	DGD2, an arabidopsis gene encoding a UDP-galactose-dependent digalactosyldiacylglycerol synthase is expressed during growth under phosphate-limiting conditions.

Q9XWS2	EXOC4_CAEEL	Exocyst complex component 4	11560892	Genetic analysis of endocytosis in Caenorhabditis elegans: coelomocyte uptake defective mutants.

P84556	TIS5_RHISA	Kunitz-type serine protease inhibitor RsTIS5	12941299	Rhipicephalus sanguineus trypsin inhibitors present in the tick larvae: isolation, characterization, and partial primary structure determination.

O75368	SH3L1_HUMAN	SH3 domain-binding glutamic acid-rich-like protein	9642120	Identification and characterization of a new human gene encoding a small protein with high homology to the proline-rich region of the SH3BGR gene.

Q01887	RYK_MOUSE	Tyrosine-protein kinase RYK	8394755	Isolation of a novel receptor tyrosine kinase cDNA expressed by developing erythroid progenitors.

Q00657	CSPG4_RAT	Chondroitin sulfate proteoglycan 4	12514214	Multiple regions of the NG2 proteoglycan inhibit neurite growth and induce growth cone collapse.

Q9R0R3	APEL_RAT	Apelin	11336787	Molecular properties of apelin: tissue distribution and receptor binding.

Q9R0X5	RPGR_MOUSE	X-linked retinitis pigmentosa GTPase regulator	9677393	Biochemical characterization and subcellular localization of the mouse retinitis pigmentosa GTPase regulator.

Q13442	HAP28_HUMAN	28 kDa heat- and acid-stable phosphoprotein	8780057	Characterization of a novel platelet-derived growth factor-associated protein.

P23285	CYPB_YEAST	Peptidyl-prolyl cis-trans isomerase B	1761234	The CYP2 gene of Saccharomyces cerevisiae encodes a cyclosporin A- sensitive peptidyl-prolyl cis-trans isomerase with an N-terminal signal sequence.

P34371	BAT42_CAEEL	BTB and MATH domain-containing protein 42	13679922	BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3.

Q6DE08	AUKBA_XENLA	Serine/threonine-protein kinase 12-A	17199039	Chromosomal enrichment and activation of the aurora B pathway are coupled to spatially regulate spindle assembly.

Q9SIS3	MA656_ARATH	65-kDa microtubule-associated protein 6	15908607	Two microtubule-associated proteins of the Arabidopsis MAP65 family function differently on microtubules.

Q15691	MARE1_HUMAN	Microtubule-associated protein RP/EB family member 1	7606712	APC binds to the novel protein EB1.

P0AEN8	FUCM_ECOLI	L-fucose mutarotase	15060078	NMR application probes a novel and ubiquitous family of enzymes that alter monosaccharide configuration.

O94498	YBS8_SCHPO	Uncharacterized N-acetyltransferase C18E5.08	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P22087	FBRL_HUMAN	rRNA 2'-O-methyltransferase fibrillarin	1846968	cDNA cloning and sequencing of human fibrillarin, a conserved nucleolar protein recognized by autoimmune antisera.

O81108	ACA2_ARATH	Calcium-transporting ATPase 2, plasma membrane-type	9422775	A novel calmodulin-regulated Ca2+-ATPase (ACA2) from Arabidopsis with an N-terminal autoinhibitory domain.

Q9R118	HTRA1_MOUSE	Serine protease HTRA1	14973287	HtrA1 serine protease inhibits signaling mediated by Tgfbeta family proteins.

P04264	K2C1_HUMAN	Keratin, type II cytoskeletal 1	1380725	Mutations in the rod domains of keratins 1 and 10 in epidermolytic hyperkeratosis.

Q13257	MD2L1_HUMAN	Mitotic spindle assembly checkpoint protein MAD2A	10700282	Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20.

O16850	FOXO_CAEEL	Forkhead box protein O	18397876	Sirtuin inhibition protects from the polyalanine muscular dystrophy protein PABPN1.

Q10364	SCK2_SCHPO	Serine/threonine-protein kinase sck2	9560431	S. pombe sck2+, a second homologue of S. cerevisiae SCH9 in fission yeast, encodes a putative protein kinase closely related to PKA in function.

P22523	MUKB_ECOLI	Chromosome partition protein mukB	1464330	E.coli MukB protein involved in chromosome partition forms a homodimer with a rod-and-hinge structure having DNA binding and ATP/GTP binding activities.

Q9P794	RU1C_SCHPO	U1 small nuclear ribonucleoprotein C	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P38715	GRE3_YEAST	NADPH-dependent aldose reductase GRE3	14562095	Global analysis of protein localization in budding yeast.

Q9ZUX7	IPT2_ARATH	tRNA dimethylallyltransferase 2	14726522	Distinct isoprenoid origins of cis- and trans-zeatin biosyntheses in Arabidopsis.

O24408	IAA18_ARATH	Auxin-responsive protein IAA18	12036262	Genetics of Aux/IAA and ARF action in plant growth and development.

O88576	S6A18_MOUSE	Sodium-dependent neutral amino acid transporter B(0)AT3	9932288	Cloning, gene structure, and genomic localization of an orphan transporter from mouse kidney with six alternatively-spliced isoforms.

P80370	DLK1_HUMAN	Protein delta homolog 1	7925474	Protein structure of fetal antigen 1 (FA1). A novel circulating human epidermal-growth-factor-like protein expressed in neuroendocrine tumors and its relation to the gene products of dlk and pG2.

P32611	RML2_YEAST	54S ribosomal protein RML2, mitochondrial	10320805	A yeast strain defective in oleic acid utilization has a mutation in the RML2 gene.

Q99JA4	CLTR1_MOUSE	Cysteinyl leukotriene receptor 1	11226226	Identification in mice of two isoforms of the cysteinyl leukotriene 1 receptor that result from alternative splicing.

P34913	HYES_HUMAN	Epoxide hydrolase 2	10862610	Identification and functional characterization of human soluble epoxide hydrolase genetic polymorphisms.

Q9LRY0	KRP5_ARATH	Cyclin-dependent kinase inhibitor 5	16376885	Arabidopsis KRPs have distinct inhibitory activity toward cyclin D2- associated kinases, including plant-specific B-type cyclin-dependent kinase.

Q9LNF2	PMEI1_ARATH	Pectinesterase inhibitor 1	17971035	Elaborate spatial patterning of cell-wall PME and PMEI at the pollen tube tip involves PMEI endocytosis, and reflects the distribution of esterified and de-esterified pectins.

Q01196	RUNX1_HUMAN	Runt-related transcription factor 1	9751710	Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors.

Q13609	DNSL3_HUMAN	Deoxyribonuclease gamma	9070308	Cloning and characterization of a novel human DNase.

Q06524	SUE1_YEAST	Protein SUE1, mitochondrial	15123691	Sue1p is required for degradation of labile forms of altered cytochromes C in yeast mitochondria.

Q07666	KHDR1_HUMAN	KH domain-containing, RNA-binding, signal transduction-associated protein 1	11585385	Human leptin signaling in human peripheral blood mononuclear cells: activation of the JAK-STAT pathway.

P01773	HV312_HUMAN	Ig heavy chain V-III region BUR	107164	Primary structure of a human IgA1 immunoglobulin. IV. Streptococcal IgA1 protease, digestion, Fab and Fc fragments, and the complete amino acid sequence of the alpha 1 heavy chain.

O35491	CLK2_MOUSE	Dual specificity protein kinase CLK2	9307018	Characterization and comparison of four serine- and arginine-rich (SR) protein kinases.

O95460	MATN4_HUMAN	Matrilin-4	9827539	Genomic organisation, alternative splicing and primary structure of human matrilin-4.

P41596	DOPR1_DROME	Dopamine receptor 1	7720859	A primordial dopamine D1-like adenylyl cyclase-linked receptor from Drosophila melanogaster displaying poor affinity for benzazepines.

Q9UQB3	CTND2_HUMAN	Catenin delta-2	9342840	Identification and localization of a neurally expressed member of the plakoglobin/armadillo multigene family.

O75369	FLNB_HUMAN	Filamin-B	16076904	The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins.

Q9HDW5	YFW6_SCHPO	UPF0644 protein PB2B4.06	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9FK25	OMT1_ARATH	Quercetin 3-O-methyltransferase 1	10700397	Functional expression of an Arabidopsis cDNA clone encoding a flavonol 3'-O-methyltransferase and characterization of the gene product.

Q12003	KP236_YEAST	Serine/threonine-protein kinase YPL236C	14562095	Global analysis of protein localization in budding yeast.

Q9SE50	BGL18_ARATH	Beta-glucosidase 18	16990135	Activation of glucosidase via stress-induced polymerization rapidly increases active pools of abscisic acid.

O00116	ADAS_HUMAN	Alkyldihydroxyacetonephosphate synthase, peroxisomal	9553082	Alkyl-dihydroxyacetonephosphate synthase. Fate in peroxisome biogenesis disorders and identification of the point mutation underlying a single enzyme deficiency.

Q6Q788	APOA5_HUMAN	Apolipoprotein A-V	12810715	Structure and interfacial properties of human apolipoprotein A-V.

P24100	CDKA1_ARATH	Cyclin-dependent kinase A-1	15863515	The cyclin-dependent kinase inhibitor KRP2 controls the onset of the endoreduplication cycle during Arabidopsis leaf development through inhibition of mitotic CDKA;1 kinase complexes.

Q96D21	RHES_HUMAN	GTP-binding protein Rhes	11976265	Identification of the monomeric G-protein, Rhes, as an efaroxan- regulated protein in the pancreatic beta-cell.

Q9R1M5	NALP5_MOUSE	NACHT, LRR and PYD domains-containing protein 5	11062459	Mater, a maternal effect gene required for early embryonic development in mice.

Q80T22	NAGT1_RAT	Sodium-dependent glucose transporter 1	12590146	Cloning and characterization of a novel Na+-dependent glucose transporter (NaGLT1) in rat kidney.

O13539	THP2_YEAST	THO complex subunit THP2	12093753	The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability.

Q99MV1	TDRD1_MOUSE	Tudor domain-containing protein 1	17141210	Tudor-related proteins TDRD1/MTR-1, TDRD6 and TDRD7/TRAP: domain composition, intracellular localization, and function in male germ cells in mice.

O13828	DCP2_SCHPO	mRNA decapping complex subunit 2	16341225	Crystal structure and functional analysis of Dcp2p from Schizosaccharomyces pombe.

Q9VYX1	ENY2_DROME	Enhancer of yellow 2 transcription factor	18034162	SAGA and a novel Drosophila export complex anchor efficient transcription and mRNA export to NPC.

P85002	CYCLF_ANNCH	Cyclopeptide F	16040066	Two cyclopeptides from the seeds of Annona cherimola.

P50747	BPL1_HUMAN	Biotin--protein ligase	18429047	Reduced half-life of holocarboxylase synthetase from patients with severe multiple carboxylase deficiency.

Q99453	PHX2B_HUMAN	Paired mesoderm homeobox protein 2B	10395798	Genomic structure and functional characterization of NBPhox (PMX2B), a homeodomain protein specific to catecholaminergic cells that is involved in second messenger-mediated transcriptional activation.

P33981	TTK_HUMAN	Dual specificity protein kinase TTK	1639825	Expression of TTK, a novel human protein kinase, is associated with cell proliferation.

O74792	SNF59_SCHPO	SWI/SNF global transcription activator complex subunit snf59	18622392	Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast.

P18297	SPRE_RAT	Sepiapterin reductase	10350607	Functionally important residues tyrosine-171 and serine-158 in sepiapterin reductase.

P25942	TNR5_HUMAN	Tumor necrosis factor receptor superfamily member 5	2475341	A B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas.

Q550L8	IFKB_DICDI	Probable serine/threonine-protein kinase ifkB	17177855	Disruption of the ifkA and ifkB genes results in altered cell adhesion, morphological defects and a propensity to form pre-stalk O cells during development of Dictyostelium.

O15315	RA51B_HUMAN	DNA repair protein RAD51 homolog 2	9512535	Isolation of novel human and mouse genes of the recA/RAD51 recombination-repair gene family.

Q99259	DCE1_HUMAN	Glutamate decarboxylase 1	1549570	Two human glutamate decarboxylases, 65-kDa GAD and 67-kDa GAD, are each encoded by a single gene.

Q12495	RLF2_YEAST	Chromatin assembly factor 1 subunit p90	11731480	The silencing complex SAS-I links histone acetylation to the assembly of repressed chromatin by CAF-I and Asf1 in Saccharomyces cerevisiae.

P22079	PERL_HUMAN	Lactoperoxidase	8964511	Cloning and sequence analysis of the human salivary peroxidase- encoding cDNA.

Q03760	PML39_YEAST	Pre-mRNA leakage protein 39	16162818	Pml39, a novel protein of the nuclear periphery required for nuclear retention of improper messenger ribonucleoparticles.

P24014	SLIT_DROME	Protein slit	2176636	Slit: an extracellular protein necessary for development of midline glia and commissural axon pathways contains both EGF and LRR domains.

Q16512	PKN1_HUMAN	Serine/threonine-protein kinase N1	20188095	Protein kinase C-related kinase targets nuclear localization signals in a subset of class IIa histone deacetylases.

P01709	LV206_HUMAN	Ig lambda chain V-II region MGC	4415202	Primary structure of the Mcg lambda chain.

Q03096	EST3_YEAST	Telomere replication protein EST3	8978029	Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes.

P13738	NHAA_ECOLI	Na(+)/H(+) antiporter nhaA	1645730	Overproduction and purification of a functional Na+/H+ antiporter coded by nhaA (ant) from Escherichia coli.

Q9ERI2	RB27A_MOUSE	Ras-related protein Rab-27A	11773082	The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain.

Q16656	NRF1_HUMAN	Nuclear respiratory factor 1	8034649	A key transcription factor for eukaryotic initiation factor-2 alpha is strongly homologous to developmental transcription factors and may link metabolic genes to cellular growth and development.

Q12229	UBX3_YEAST	UBX domain-containing protein 3	15258615	Shp1 and Ubx2 are adaptors of Cdc48 involved in ubiquitin-dependent protein degradation.

O94362	YHOF_SCHPO	Uncharacterized GTP-binding protein C428.15	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P63012	RAB3A_RAT	Ras-related protein Rab-3A	10025402	Structural basis of Rab effector specificity: crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A.

Q9P7C3	MNS1_SCHPO	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase	16079177	Characterization of Schizosaccharomyces pombe ER alpha-mannosidase: a reevaluation of the role of the enzyme on ER-associated degradation.

Q9Y7R4	SET1_SCHPO	Histone-lysine N-methyltransferase, H3 lysine-4 specific	12193658	Histone H3 lysine 4 methylation is mediated by Set1 and promotes maintenance of active chromatin states in fission yeast.

Q9VMA3	CUP_DROME	Protein cup	9118812	The Drosophila gene fs(2)cup interacts with otu to define a cytoplasmic pathway required for the structure and function of germ- line chromosomes.

Q9XYF4	ICENC_DROME	Caspase Nc	10200258	DRONC, an ecdysone-inducible Drosophila caspase.

P36586	YPT5_SCHPO	GTP-binding protein ypt5	8374169	Schizosaccharomyces pombe ypt5: a homologue of the rab5 endosome fusion regulator.

P30518	V2R_HUMAN	Vasopressin V2 receptor	8882880	Two novel mutations in the aquaporin-2 and the vasopressin V2 receptor genes in patients with congenital nephrogenic diabetes insipidus.

Q6Q4D0	BRU1_ARATH	Protein BRUSHY 1	15125773	A novel Arabidopsis gene TONSOKU is required for proper cell arrangement in root and shoot apical meristems.

Q9PTJ3	RBTN2_DANRE	Rhombotin-2	17090656	The transcription factors Scl and Lmo2 act together during development of the hemangioblast in zebrafish.

O17087	GLD2_CAEEL	Poly(A) RNA polymerase gld-2	12239571	A regulatory cytoplasmic poly(A) polymerase in Caenorhabditis elegans.

P23292	KC12_YEAST	Casein kinase I homolog 2	1627830	Two genes in Saccharomyces cerevisiae encode a membrane-bound form of casein kinase-1.

Q3E747	YL363_YEAST	Uncharacterized protein YLR363W-A	14562095	Global analysis of protein localization in budding yeast.

O76093	FGF18_HUMAN	Fibroblast growth factor 18	9742123	FGF-18, a novel member of the fibroblast growth factor family, stimulates hepatic and intestinal proliferation.

Q7Z434	MAVS_HUMAN	Mitochondrial antiviral-signaling protein	19631370	RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway.

O13728	AIN1_SCHPO	Alpha-actinin-like protein 1	11294907	Roles of a fimbrin and an alpha-actinin-like protein in fission yeast cell polarization and cytokinesis.

Q9EQC9	CXXC4_RAT	CXXC-type zinc finger protein 4	11113207	Inhibition of the Wnt signaling pathway by Idax, a novel Dvl-binding protein.

Q06486	KC1D_RAT	Casein kinase I isoform delta	8454611	Molecular cloning, expression, and characterization of a 49- kilodalton casein kinase I isoform from rat testis.

Q9Y5I2	PCDAA_HUMAN	Protocadherin alpha-10	10380929	A striking organization of a large family of human neural cadherin- like cell adhesion genes.

Q8L4R0	TGD1_ARATH	Protein TRIGALACTOSYLDIACYLGLYCEROL 1, chloroplastic	12743031	A permease-like protein involved in ER to thylakoid lipid transfer in Arabidopsis.

Q9MA41	CTL1_ARATH	Chitinase-like protein 1	20007445	Chitinase-like protein CTL1 plays a role in altering root system architecture in response to multiple environmental conditions.

Q9NXR7	BRE_HUMAN	BRCA1-A complex subunit BRE	15465831	A death receptor-associated anti-apoptotic protein, BRE, inhibits mitochondrial apoptotic pathway.

O45657	PLX2_CAEEL	Plexin-2	17507686	The plexin PLX-2 and the ephrin EFN-4 have distinct roles in MAB- 20/semaphorin 2A signaling in Caenorhabditis elegans morphogenesis.

Q9UNS2	CSN3_HUMAN	COP9 signalosome complex subunit 3	9535219	A novel protein complex involved in signal transduction possessing similarities to 26S proteasome subunits.

Q6LEM5	BNP1_BOTJA	Bradykinin-potentiating and C-type natriuretic peptides	9037028	Cloning and sequence analysis of a Bothrops jararaca cDNA encoding a precursor of seven bradykinin-potentiating peptides and a C-type natriuretic peptide.

P41735	CAT5_YEAST	Catabolite repression protein CAT5	9452453	Yeast Clk-1 homologue (Coq7/Cat5) is a mitochondrial protein in coenzyme Q synthesis.

P04351	IL2_MOUSE	Interleukin-2	8262055	Definition and spatial location of mouse interleukin-2 residues that interact with its heterotrimeric receptor.

Q96PE7	MCEE_HUMAN	Methylmalonyl-CoA epimerase, mitochondrial	11481338	Identification of the human methylmalonyl-CoA racemase gene based on the analysis of prokaryotic gene arrangements. Implications for decoding the human genome.

Q61337	BAD_MOUSE	Bcl2 antagonist of cell death	11717309	Identification of a novel phosphorylation site, Ser-170, as a regulator of bad pro-apoptotic activity.

P08047	SP1_HUMAN	Transcription factor Sp1	3139301	O-glycosylation of eukaryotic transcription factors: implications for mechanisms of transcriptional regulation.

P53920	NM111_YEAST	Pro-apoptotic serine protease NMA111	16608876	The inhibitor-of-apoptosis protein Bir1p protects against apoptosis in S. cerevisiae and is a substrate for the yeast homologue of Omi/HtrA2.

Q15070	OXA1L_HUMAN	Mitochondrial inner membrane protein OXA1L	9247084	Sequence and structure of the human OXA1L gene and its upstream elements.

Q9UHM6	OPN4_HUMAN	Melanopsin	15674244	Addition of human melanopsin renders mammalian cells photoresponsive.

P24100	CDKA1_ARATH	Cyclin-dependent kinase A-1	17369369	T-loop phosphorylation of Arabidopsis CDKA;1 is required for its function and can be partially substituted by an aspartate residue.

Q9NRQ2	PLS4_HUMAN	Phospholipid scramblase 4	10930526	Identification of three new members of the phospholipid scramblase gene family.

Q91689	ZIC2A_XENLA	Zinc finger protein ZIC 2-A	9739105	Xenopus Zic family and its role in neural and neural crest development.

Q9NGX9	CP302_DROME	Cytochrome P450 302a1, mitochondrial	12177427	Molecular and biochemical characterization of two P450 enzymes in the ecdysteroidogenic pathway of Drosophila melanogaster.

P53236	RSC1_YEAST	Chromatin structure-remodeling complex subunit RSC1	12702296	Functional differences between RSC1 and RSC2, components of a for growth essential chromatin-remodeling complex of Saccharomyces cerevisiae, during the sporulation process.

Q3UQ28	PXDN_MOUSE	Peroxidasin homolog	19590037	Peroxidasin is secreted and incorporated into the extracellular matrix of myofibroblasts and fibrotic kidney.

Q8CJ53	CIP4_MOUSE	Cdc42-interacting protein 4	17189207	Gapex-5, a Rab31 guanine nucleotide exchange factor that regulates Glut4 trafficking in adipocytes.

P40967	PME17_HUMAN	Melanocyte protein Pmel 17	15096515	Epitope mapping of the melanosomal matrix protein gp100 (PMEL17): rapid processing in the endoplasmic reticulum and glycosylation in the early Golgi compartment.

Q92830	KAT2A_HUMAN	Histone acetyltransferase KAT2A	18206972	A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing.

Q9S7Q2	PP124_ARATH	Pentatricopeptide repeat-containing protein At1g74850, chloroplastic	16326926	pTAC2, -6, and -12 are components of the transcriptionally active plastid chromosome that are required for plastid gene expression.

Q9ZUY3	AROD3_ARATH	Arogenate dehydratase 3, chloroplastic	17726025	Phenylalanine biosynthesis in Arabidopsis thaliana. Identification and characterization of arogenate dehydratases.

Q15831	STK11_HUMAN	Serine/threonine-protein kinase 11	17216128	Association of LKB1 with a WD-repeat protein WDR6 is implicated in cell growth arrest and p27(Kip1) induction.

P54939	TLN1_CHICK	Talin-1	14702644	Vinculin activation by talin through helical bundle conversion.

Q9SY65	ASK18_ARATH	SKP1-like protein 18	19682297	An F-box gene, CPR30, functions as a negative regulator of the defense response in Arabidopsis.

O77150	IM02_DROME	Immune-induced peptide 2	12171930	Peptidomics of the larval Drosophila melanogaster central nervous system.

Q9UKL6	PPCT_HUMAN	Phosphatidylcholine transfer protein	10500206	Mice without phosphatidylcholine transfer protein have no defects in the secretion of PC into bile or into the lung airspaces.

Q91876	MCM7A_XENLA	DNA replication licensing factor mcm7-A	16369567	The ATPase activity of MCM2-7 is dispensable for pre-RC assembly but is required for DNA unwinding.

Q28CH2	CPEB3_XENTR	Cytoplasmic polyadenylation element-binding protein 3	18472403	A functional screen for genes involved in Xenopus pronephros development.

Q04924	GLU2B_YEAST	Glucosidase 2 subunit beta	16373354	Yeast GTB1 encodes a subunit of glucosidase II required for glycoprotein processing in the endoplasmic reticulum.

P47987	PLLP_RAT	Plasmolipin	8714710	Full-lenth cloning, expression and cellular localization of rat plasmolipin mRNA, a proteolipid of PNS and CNS.

Q6T486	RBRA_DICDI	Probable E3 ubiquitin-protein ligase rbrA	17031003	A putative Ariadne-like ubiquitin ligase is required for Dictyostelium discoideum development.

D4GZE7	SAMP2_HALVD	Small archaeal modifier protein 2	20054389	Ubiquitin-like small archaeal modifier proteins (SAMPs) in Haloferax volcanii.

P51611	HCFC1_MESAU	Host cell factor 1	9087427	A single-point mutation in HCF causes temperature-sensitive cell- cycle arrest and disrupts VP16 function.

P62746	RHOB_MOUSE	Rho-related GTP-binding protein RhoB	11564874	RhoB is dispensable for mouse development, but it modifies susceptibility to tumor formation as well as cell adhesion and growth factor signaling in transformed cells.

P92186	LIN28_CAEEL	Protein lin-28	11884032	Two genetic circuits repress the Caenorhabditis elegans heterochronic gene lin-28 after translation initiation.

Q9BST9	RTKN_HUMAN	Rhotekin	10940294	The PDZ protein TIP-1 interacts with the Rho effector rhotekin and is involved in Rho signaling to the serum response element.

P78962	ATF21_SCHPO	Transcription factor atf21	8824587	Conjugation, meiosis, and the osmotic stress response are regulated by Spc1 kinase through Atf1 transcription factor in fission yeast.

Q2M3G0	ABCB5_HUMAN	ATP-binding cassette sub-family B member 5	12960149	Regulation of progenitor cell fusion by ABCB5 P-glycoprotein, a novel human ATP-binding cassette transporter.

P00481	OTC_RAT	Ornithine carbamoyltransferase, mitochondrial	2290837	Site-directed mutagenesis of Arg60 and Cys271 in ornithine transcarbamylase from rat liver.

P23142	FBLN1_HUMAN	Fibulin-1	2269669	Fibulin is an extracellular matrix and plasma glycoprotein with repeated domain structure.

P40075	SCS2_YEAST	Vesicle-associated membrane protein-associated protein SCS2	12727870	A conserved ER targeting motif in three families of lipid binding proteins and in Opi1p binds VAP.

P38351	PAF1_YEAST	RNA polymerase II-associated protein 1	12242279	RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach.

Q9C5X2	CCJ18_ARATH	Cyclin-J18	11389963	A novel and highly divergent Arabidopsis cyclin isolated by complementation in budding yeast.

O88597	BECN1_MOUSE	Beclin-1	17589504	Ambra1 regulates autophagy and development of the nervous system.

P91745	PE48A_LUCCU	Peritrophin-48	9639876	cDNA and deduced amino acid sequences of a peritrophic membrane glycoprotein, 'peritrophin-48', from the larvae of Lucilia cuprina.

Q38960	LWD2_ARATH	WD repeat-containing protein LWD2	18676661	Two new clock proteins, LWD1 and LWD2, regulate Arabidopsis photoperiodic flowering.

Q9Y2X7	GIT1_HUMAN	ARF GTPase-activating protein GIT1	19041750	Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma.

Q9Y5R6	DMRT1_HUMAN	Doublesex- and mab-3-related transcription factor 1	10332030	A region of human chromosome 9p required for testis development contains two genes related to known sexual regulators.

P91276	IMA2_CAEEL	Importin subunit alpha-2	11311162	Germline and developmental roles of the nuclear transport factor importin alpha3 in C. elegans.

P38138	GLU2A_YEAST	Glucosidase 2 subunit alpha	16373354	Yeast GTB1 encodes a subunit of glucosidase II required for glycoprotein processing in the endoplasmic reticulum.

Q80YE7	DAPK1_MOUSE	Death-associated protein kinase 1	11485996	Identification of a new form of death-associated protein kinase that promotes cell survival.

Q674X7	KAZRN_HUMAN	Kazrin	15337775	Kazrin, a novel periplakin-interacting protein associated with desmosomes and the keratinocyte plasma membrane.

P40562	MPH1_YEAST	ATP-dependent DNA helicase MPH1	15634678	Saccharomyces cerevisiae MPH1 gene, required for homologous recombination-mediated mutation avoidance, encodes a 3' to 5' DNA helicase.

O74535	CPSFX_SCHPO	Cleavage and polyadenylation factor complex subunit C74.02c	14617822	A comparative analysis of an orthologous proteomic environment in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe.

Q9LY14	MSRA3_ARATH	Peptide methionine sulfoxide reductase A3	10806242	Differential regulation of plastidial and cytosolic isoforms of peptide methionine sulfoxide reductase in Arabidopsis.

Q55G87	CANB1_DICDI	Calcineurin subunit B type 1	11352578	Unconventional mRNA processing in the expression of two calcineurin B isoforms in Dictyostelium.

Q9QZV9	NXT1_MOUSE	NTF2-related export protein 1	10567585	Identification of an NTF2-related factor that binds Ran-GTP and regulates nuclear protein export.

P39995	EAF5_YEAST	Chromatin modification-related protein EAF5	15485911	The Yaf9 component of the SWR1 and NuA4 complexes is required for proper gene expression, histone H4 acetylation, and Htz1 replacement near telomeres.

P19880	YAP1_YEAST	AP-1-like transcription factor YAP1	9130715	Regulation of yAP-1 nuclear localization in response to oxidative stress.

Q5C9Z4	NOM1_HUMAN	Nucleolar MIF4G domain-containing protein 1	17965019	NOM1 targets protein phosphatase I to the nucleolus.

P01715	LV401_HUMAN	Ig lambda chain V-IV region Bau	4435717	Pattern of antibody structure, the primary structure of monoclonal immunoglobulin L-chain of the lambda-type, subgroup IV (Bence-Jones protein Bau.).

Q03135	CAV1_HUMAN	Caveolin-1	16807357	Translocation of endothelial nitric-oxide synthase involves a ternary complex with caveolin-1 and NOSTRIN.

Q9UHH9	IP6K2_HUMAN	Inositol hexakisphosphate kinase 2	10574768	Synthesis of diphosphoinositol pentakisphosphate by a newly identified family of higher inositol polyphosphate kinases.

P93026	VSR1_ARATH	Vacuolar-sorting receptor 1	10397763	The plant vesicle-associated SNARE AtVTI1a likely mediates vesicle transport from the trans-Golgi network to the prevacuolar compartment.

Q92355	SEN1_SCHPO	Helicase sen1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P38348	HSM3_YEAST	DNA mismatch repair protein HSM3	19446322	Multiple assembly chaperones govern biogenesis of the proteasome regulatory particle base.

Q08421	YO051_YEAST	Uncharacterized protein YOR051C	10684247	The yeast nuclear pore complex: composition, architecture, and transport mechanism.

P83436	COG7_HUMAN	Conserved oligomeric Golgi complex subunit 7	11980916	Characterization of a mammalian Golgi-localized protein complex, COG, that is required for normal Golgi morphology and function.

Q07478	SUB2_YEAST	ATP-dependent RNA helicase SUB2	15942929	The Saccharomyces cerevisiae Sub2 protein suppresses heterochromatic silencing at telomeres and subtelomeric genes.

Q9NPY3	C1QR1_HUMAN	Complement component C1q receptor	11994479	Human C1qRp is identical with CD93 and the mNI-11 antigen but does not bind C1q.

O13808	YE0B_SCHPO	Uncharacterized protein C17H9.11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P42345	MTOR_HUMAN	Serine/threonine-protein kinase mTOR	12150925	mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the growth machinery.

O15055	PER2_HUMAN	Period circadian protein homolog 2	9427249	Two period homologs: circadian expression and photic regulation in the suprachiasmatic nuclei.

Q9NPF5	DMAP1_HUMAN	DNA methyltransferase 1-associated protein 1	14966270	Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans.

Q9W3R7	ATG5_DROME	Autophagy protein 5	15296714	Role and regulation of starvation-induced autophagy in the Drosophila fat body.

P36049	EBP2_YEAST	rRNA-processing protein EBP2	10849420	The budding yeast homolog of the human EBNA1-binding protein 2 (Ebp2p) is an essential nucleolar protein required for pre-rRNA processing.

Q13813	SPTA2_HUMAN	Spectrin alpha chain, brain	15328537	Emerin caps the pointed end of actin filaments: evidence for an actin cortical network at the nuclear inner membrane.

P01095	IPB2_YEAST	Protease B inhibitors 2 and 1	9657146	LMA1 binds to vacuoles at Sec18p (NSF), transfers upon ATP hydrolysis to a t-SNARE (Vam3p) complex, and is released during fusion.

Q9Z0F7	SYUG_MOUSE	Gamma-synuclein	9801372	Persyn, a member of the synuclein family, has a distinct pattern of expression in the developing nervous system.

Q13438	OS9_HUMAN	Protein OS-9	18502753	Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiP.

O00899	GAPA_DICDI	Ras GTPase-activating-like protein gapA	12771188	A STAT-regulated, stress-induced signalling pathway in Dictyostelium.

Q9P7S4	TAF4_SCHPO	Transcription initiation factor TFIID subunit 4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9ZPW2	APC10_ARATH	Anaphase-promoting complex subunit 10	17944809	Specialization of CDC27 function in the Arabidopsis thaliana anaphase-promoting complex (APC/C).

Q12834	CDC20_HUMAN	Cell division cycle protein 20 homolog	15525512	Phosphorylation of Cdc20 by Bub1 provides a catalytic mechanism for APC/C inhibition by the spindle checkpoint.

P46677	TAF1_YEAST	Transcription initiation factor TFIID subunit 1	12138208	Molecular characterization of Saccharomyces cerevisiae TFIID.

Q04592	PCSK5_MOUSE	Proprotein convertase subtilisin/kexin type 5	8468318	Identification and functional expression of a new member of the mammalian Kex2-like processing endoprotease family: its striking structural similarity to PACE4.

P40689	TSL_DROME	Torso-like protein	12814553	The Drosophila embryonic patterning determinant torsolike is a component of the eggshell.

Q61060	FOXD3_MOUSE	Forkhead box protein D3	11684651	The winged-helix transcription factor Foxd3 suppresses interneuron differentiation and promotes neural crest cell fate.

P13987	CD59_HUMAN	CD59 glycoprotein	1381503	Structure of the CD59-encoding gene: further evidence of a relationship to murine lymphocyte antigen Ly-6 protein.

Q84MM9	MOC_ORYSJ	Protein MONOCULM 1	12687001	Control of tillering in rice.

Q3UTH8	ARHG9_MOUSE	Rho guanine nucleotide exchange factor 9	11168555	Distribution of transcripts for the brain-specific GDP/GTP exchange factor collybistin in the developing mouse brain.

O74815	PPK27_SCHPO	Serine/threonine-protein kinase ppk27	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P27809	KRE2_YEAST	Glycolipid 2-alpha-mannosyltransferase	1541391	Yeast KRE2 defines a new gene family encoding probable secretory proteins, and is required for the correct N-glycosylation of proteins.

Q9EQQ2	YIPF5_MOUSE	Protein YIPF5	15254263	Cdc2 kinase-dependent disassembly of endoplasmic reticulum (ER) exit sites inhibits ER-to-Golgi vesicular transport during mitosis.

Q9H0Z9	RBM38_HUMAN	RNA-binding protein 38	17050675	RNPC1, an RNA-binding protein and a target of the p53 family, is required for maintaining the stability of the basal and stress-induced p21 transcript.

P47095	MTNB_YEAST	Methylthioribulose-1-phosphate dehydratase	18625006	A complete inventory of all enzymes in the eukaryotic methionine salvage pathway.

O35881	P2Y14_RAT	P2Y purinoceptor 14	9295203	The isolation and characterization of a novel G protein-coupled receptor regulated by immunologic challenge.

P62837	UB2D2_HUMAN	Ubiquitin-conjugating enzyme E2 D2	18359941	Members of the E2D (UbcH5) family mediate the ubiquitination of the conserved cysteine of Pex5p, the peroxisomal import receptor.

Q16798	MAON_HUMAN	NADP-dependent malic enzyme, mitochondrial	7818469	Purification, cDNA cloning and heterologous expression of the human mitochondrial NADP(+)-dependent malic enzyme.

P39010	AKR1_YEAST	Palmitoyltransferase AKR1	9243510	The ankyrin repeat-containing protein Akr1p is required for the endocytosis of yeast pheromone receptors.

P04041	GPX1_RAT	Glutathione peroxidase 1	1640255	Dietary selenium stabilizes glutathione peroxidase mRNA in rat liver.

Q15843	NEDD8_HUMAN	NEDD8	9694792	A new NEDD8-ligating system for cullin-4A.

Q60793	KLF4_MOUSE	Krueppel-like factor 4	8940147	A gene for a novel zinc-finger protein expressed in differentiated epithelial cells and transiently in certain mesenchymal cells.

Q06344	ESF1_YEAST	Pre-rRNA-processing protein ESF1	14690591	Assigning function to yeast proteins by integration of technologies.

P91443	HUM6_CAEEL	Unconventional myosin heavy chain 6	12808046	Caenorhabditis elegans UNC-98, a C2H2 Zn finger protein, is a novel partner of UNC-97/PINCH in muscle adhesion complexes.

Q9P7Q8	PMO25_SCHPO	Mo25-like protein	16096637	Fission yeast MO25 protein is localized at SPB and septum and is essential for cell morphogenesis.

P11362	FGFR1_HUMAN	Basic fibroblast growth factor receptor 1	2167437	Diverse forms of a receptor for acidic and basic fibroblast growth factors.

O60052	FNTA_SCHPO	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	9781874	Characterization of the geranylgeranyl transferase type I from Schizosaccharomyces pombe.

Q0DVX2	RH50_ORYSJ	DEAD-box ATP-dependent RNA helicase 50	18441339	OsBIRH1, a DEAD-box RNA helicase with functions in modulating defence responses against pathogen infection and oxidative stress.

Q9UN88	GBRT_HUMAN	Gamma-aminobutyric acid receptor subunit theta	10449790	Theta, a novel gamma-aminobutyric acid type A receptor subunit.

P55273	CDN2D_HUMAN	Cyclin-dependent kinase 4 inhibitor D	8741839	Isolation and characterization of p19INK4d, a p16-related inhibitor specific to CDK6 and CDK4.

P39984	HAT2_YEAST	Histone acetyltransferase type B subunit 2	14761951	Hif1 is a component of yeast histone acetyltransferase B, a complex mainly localized in the nucleus.

P23503	NAR1_YEAST	Cytosolic Fe-S cluster assembly factor NAR1	16314508	The essential WD40 protein Cia1 is involved in a late step of cytosolic and nuclear iron-sulfur protein assembly.

P32944	SWE1_YEAST	Mitosis inhibitor protein kinase SWE1	10805747	Septin-dependent assembly of a cell cycle-regulatory module in Saccharomyces cerevisiae.

D3KCC4	CRNS1_CHICK	Carnosine synthase 1	20097752	Molecular identification of carnosine synthase as ATP-grasp domain- containing protein 1 (ATPGD1).

P32927	IL3RB_HUMAN	Cytokine receptor common subunit beta	1702217	Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): reconstitution of a high-affinity GM-CSF receptor.

Q84MC2	LOG8_ARATH	Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG8	17048257	X-ray crystal structures of the conserved hypothetical proteins from Arabidopsis thaliana gene loci At5g11950 and At2g37210.

Q39009	DMC1_ARATH	Meiotic recombination protein DMC1 homolog	9025299	AtDMC1, the Arabidopsis homologue of the yeast DMC1 gene: characterization, transposon-induced allelic variation and meiosis- associated expression.

O74763	YBE8_SCHPO	Uncharacterized WD repeat-containing protein C17D11.08	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P18064	GPA1_ARATH	Guanine nucleotide-binding protein alpha-1 subunit	16582010	The plastid protein THYLAKOID FORMATION1 and the plasma membrane G- protein GPA1 interact in a novel sugar-signaling mechanism in Arabidopsis.

Q8K424	TRPV3_MOUSE	Transient receptor potential cation channel subfamily V member 3	12016205	A heat-sensitive TRP channel expressed in keratinocytes.

Q91UZ5	IMPA2_MOUSE	Inositol monophosphatase 2	11418250	Characterization of two genes, Impa1 and Impa2 encoding mouse myo- inositol monophosphatases.

Q95VP3	GOBP1_EPIPO	General odorant-binding protein 1	12530222	Pheromone binding proteins of Epiphyas postvittana (Lepidoptera: Tortricidae) are encoded at a single locus.

Q9UHB9	SRP68_HUMAN	Signal recognition particle 68 kDa protein	10618370	Signal recognition particle components in the nucleolus.

P70060	LDB1_XENLA	LIM domain-binding protein 1	10926781	Xlim-1 and LIM domain binding protein 1 cooperate with various transcription factors in the regulation of the goosecoid promoter.

Q9P6R3	YOH7_SCHPO	Uncharacterized protein C13E7.07	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P53258	GYP2_YEAST	GTPase-activating protein GYP2	10559187	Two new members of a family of Ypt/Rab GTPase activating proteins. Promiscuity of substrate recognition.

A2SWM2	SPNS2_DANRE	Protein spinster homolog 2	19074308	The sphingolipid transporter spns2 functions in migration of zebrafish myocardial precursors.

P53189	SCW11_YEAST	Probable family 17 glucosidase SCW11	9748433	New potential cell wall glucanases of Saccharomyces cerevisiae and their involvement in mating.

P82909	RT36_HUMAN	28S ribosomal protein S36, mitochondrial	11279123	The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present.

Q02817	MUC2_HUMAN	Mucin-2	19432394	Proteomic analyses of the two mucus layers of the colon barrier reveal that their main component, the Muc2 mucin, is strongly bound to the Fcgbp protein.

P27695	APEX1_HUMAN	DNA-(apurinic or apyrimidinic site) lyase	1380454	Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme.

Q9VT57	CDK8_DROME	Cell division protein kinase 8	17290221	Distinct roles for Mediator Cdk8 module subunits in Drosophila development.

Q9BVW5	TIPIN_HUMAN	TIMELESS-interacting protein	17102137	Human Tim/Timeless-interacting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpoint.

Q14181	DPOA2_HUMAN	DNA polymerase alpha subunit B	8223465	The role of the 70 kDa subunit of human DNA polymerase alpha in DNA replication.

Q05676	SOM1_YEAST	Protein SOM1, mitochondrial	8879245	SOM1, a small new gene required for mitochondrial inner membrane peptidase function in Saccharomyces cerevisiae.

P04406	G3P_HUMAN	Glyceraldehyde-3-phosphate dehydrogenase	15628863	Oxidative stress-responsive intracellular regulation specific for the angiostatic form of human tryptophanyl-tRNA synthetase.

Q04206	TF65_HUMAN	Transcription factor p65	10498867	NF-kappaB subunit p65 binds to 53BP2 and inhibits cell death induced by 53BP2.

Q6UWZ7	F175A_HUMAN	BRCA1-A complex subunit Abraxas	19261748	MERIT40 facilitates BRCA1 localization and DNA damage repair.

Q04659	CSM3_YEAST	Chromosome segregation in meiosis protein 3	16219777	Genetic analysis of Saccharomyces cerevisiae H2A serine 129 mutant suggests a functional relationship between H2A and the sister- chromatid cohesion partners Csm3-Tof1 for the repair of topoisomerase I-induced DNA damage.

Q18510	ARL6_CAEEL	ADP-ribosylation factor-like protein 6	15314642	Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Biedl syndrome.

P54760	EPHB4_HUMAN	Ephrin type-B receptor 4	8188704	Cloning and characterization of HTK, a novel transmembrane tyrosine kinase of the EPH subfamily.

Q03157	APLP1_MOUSE	Amyloid-like protein 1	10460257	Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1.

P52890	ATF1_SCHPO	Transcription factor atf1	9135083	Schizosaccharomyces pombe gad7+ encodes a phosphoprotein with a bZIP domain, which is required for proper G1 arrest and gene expression under nitrogen starvation.

P12830	CADH1_HUMAN	Cadherin-1	8033105	E-cadherin gene mutations provide clues to diffuse type gastric carcinomas.

Q7L1S5	CHST9_HUMAN	Carbohydrate sulfotransferase 9	11139592	Molecular cloning and expression of an N-acetylgalactosamine-4-O- sulfotransferase that transfers sulfate to terminal and non-terminal beta 1,4-linked N-acetylgalactosamine.

P49333	ETR1_ARATH	Ethylene receptor 1	7759498	The ethylene response mediator ETR1 from Arabidopsis forms a disulfide-linked dimer.

P48523	CADH4_ARATH	Cinnamyl alcohol dehydrogenase 4	15937231	CINNAMYL ALCOHOL DEHYDROGENASE-C and -D are the primary genes involved in lignin biosynthesis in the floral stem of Arabidopsis.

P61586	RHOA_HUMAN	Transforming protein RhoA	8617235	The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase.

Q8IY57	YAF2_HUMAN	YY1-associated factor 2	9016636	Yeast two-hybrid cloning of a novel zinc finger protein that interacts with the multifunctional transcription factor YY1.

Q02790	FKBP4_HUMAN	Peptidyl-prolyl cis-trans isomerase FKBP4	1376003	Association of a 59-kilodalton immunophilin with the glucocorticoid receptor complex.

O74833	DNLI4_SCHPO	DNA ligase 4	11029034	Protection of telomeres by the Ku protein in fission yeast.

Q7KHG2	JING_DROME	Zinc finger protein jing	18036784	A screen for genes that function in leg disc regeneration in Drosophila melanogaster.

Q96PU4	UHRF2_HUMAN	E3 ubiquitin-protein ligase UHRF2	15178429	NIRF induces G1 arrest and associates with Cdk2.

Q9UBE8	NLK_HUMAN	Serine/threonine-protein kinase NLK	16714285	NARF, an nemo-like kinase (NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF).

P02538	K2C6A_HUMAN	Keratin, type II cytoskeletal 6A	7545493	Mutation of a type II keratin gene (K6a) in pachyonychia congenita.

Q62717	CAPS1_RAT	Calcium-dependent secretion activator 1	1516133	A novel 145 kd brain cytosolic protein reconstitutes Ca(2+)-regulated secretion in permeable neuroendocrine cells.

P18886	CPT2_RAT	Carnitine O-palmitoyltransferase 2, mitochondrial	9136891	Functional characterization of mitochondrial carnitine palmitoyltransferases I and II expressed in the yeast Pichia pastoris.

Q8IN94	OSA_DROME	Trithorax group protein osa	9271118	Eyelid antagonizes wingless signaling during Drosophila development and has homology to the Bright family of DNA-binding proteins.

Q9VUL9	FUCTA_DROME	Glycoprotein 3-alpha-L-fucosyltransferase A	11382750	Identification of core alpha1,3-fucosylated glycans and cloning of the requisite fucosyltransferase cDNA from Drosophila melanogaster: Potential basis of the neural anti-horseradish peroxidase epitope.

Q03430	RSM28_YEAST	37S ribosomal protein RSM28, mitochondrial	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Q9V4S8	CSN7_DROME	COP9 signalosome complex subunit 7	10531038	The COP9 signalosome is essential for development of Drosophila melanogaster.

P46695	IEX1_HUMAN	Radiation-inducible immediate-early gene IEX-1	9196025	Identification and characterization of a novel monocyte/macrophage differentiation-dependent gene that is responsive to lipopolysaccharide, ceramide, and lysophosphatidylcholine.

O94522	RSC7_SCHPO	Chromatin structure-remodeling complex subunit rsc7	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q39231	SUC2_ARATH	Sucrose transport protein SUC2	11087840	Genetic evidence for the in planta role of phloem-specific plasma membrane sucrose transporters.

Q9C958	SRK2B_ARATH	Serine/threonine-protein kinase SRK2B	15292193	Identification of nine sucrose nonfermenting 1-related protein kinases 2 activated by hyperosmotic and saline stresses in Arabidopsis thaliana.

P82808	GFPT1_RAT	Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1	10898949	Purification and characterization of glutamine:fructose 6-phosphate amidotransferase from rat liver.

P91303	VATG_CAEEL	Probable V-type proton ATPase subunit G	16005300	The vacuolar H+ -ATPase mediates intracellular acidification required for neurodegeneration in C. elegans.

Q9Z0G9	CLD3_MOUSE	Claudin-3	10508613	Ca(2+)-independent cell-adhesion activity of claudins, a family of integral membrane proteins localized at tight junctions.

Q7LKZ5	FAM50_SCHPO	FAM50 family protein C1020.12c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9ESE1	LRBA_MOUSE	Lipopolysaccharide-responsive and beige-like anchor protein	11254716	Identification of a novel lipopolysaccharide-inducible gene with key features of both A kinase anchor proteins and chs1/beige proteins.

Q63185	E2AK1_RAT	Eukaryotic translation initiation factor 2-alpha kinase 1	7908290	Cloning and characterization of cDNA encoding rat hemin-sensitive initiation factor-2 alpha (eIF-2 alpha) kinase. Evidence for multitissue expression.

P38222	RKM3_YEAST	Ribosomal N-lysine methyltransferase 3	18957409	Identification of two SET domain proteins required for methylation of lysine residues in yeast ribosomal protein Rpl42ab.

Q07953	SDO1_YEAST	Ribosome maturation protein SDO1	17353896	The Shwachman-Bodian-Diamond syndrome protein mediates translational activation of ribosomes in yeast.

Q8GZB6	SUVH4_ARATH	Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH4	11898023	Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase.

O14100	ZDS1_SCHPO	Protein zds1	16322512	zds1, a novel gene encoding an ortholog of Zds1 and Zds2, controls sexual differentiation, cell wall integrity and cell morphology in fission yeast.

Q99P91	GPNMB_MOUSE	Transmembrane glycoprotein NMB	12638126	mRNA expression of the murine glycoprotein (transmembrane) nmb (Gpnmb) gene is linked to the developing retinal pigment epithelium and iris.

Q99MQ4	ASPN_MOUSE	Asporin	17827158	Mechanisms for asporin function and regulation in articular cartilage.

Q9NXB0	MKS1_HUMAN	Meckel syndrome type 1 protein	17185389	The Meckel-Gruber syndrome proteins MKS1 and meckelin interact and are required for primary cilium formation.

Q06337	EAF1_YEAST	Chromatin modification-related protein EAF1	15485911	The Yaf9 component of the SWR1 and NuA4 complexes is required for proper gene expression, histone H4 acetylation, and Htz1 replacement near telomeres.

Q9SYX2	SPA1_ARATH	Protein SUPPRESSOR OF PHYA-105 1	16813572	The central coiled-coil domain and carboxyl-terminal WD-repeat domain of Arabidopsis SPA1 are responsible for mediating repression of light signaling.

Q09914	RHO1_SCHPO	GTP-binding protein rho1	9372443	Localisation of the Schizosaccharomyces pombe rho1p GTPase and its involvement in the organisation of the actin cytoskeleton.

Q62768	UN13A_RAT	Protein unc-13 homolog A	8999968	Direct interaction of the rat unc-13 homologue Munc13-1 with the N terminus of syntaxin.

Q9VUX2	MIB_DROME	E3 ubiquitin-protein ligase mind-bomb	15829515	The ubiquitin ligase Drosophila Mind bomb promotes Notch signaling by regulating the localization and activity of Serrate and Delta.

O77469	FBLN1_CAEEL	Fibulin-1	9923656	Identification of chicken and C. elegans fibulin-1 homologs and characterization of the C. elegans fibulin-1 gene.

Q9P4X1	YKV5_SCHPO	Thioredoxin domain-containing protein C959.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P29350	PTN6_HUMAN	Tyrosine-protein phosphatase non-receptor type 6	18604210	An essential function for beta-arrestin 2 in the inhibitory signaling of natural killer cells.

Q15633	TRBP2_HUMAN	RISC-loading complex subunit TARBP2	15973356	TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing.

Q62838	MUSK_RAT	Muscle, skeletal receptor tyrosine protein kinase	7546737	Receptor tyrosine kinase specific for the skeletal muscle lineage: expression in embryonic muscle, at the neuromuscular junction, and after injury.

Q05961	OAS1_RAT	2'-5'-oligoadenylate synthase 1	7764002	Transgenic potato plants expressing mammalian 2'-5' oligoadenylate synthetase are protected from potato virus X infection under field conditions.

P67984	RL22_MOUSE	60S ribosomal protein L22	8135813	A novel heparin-binding protein, HBp15, is identified as mammalian ribosomal protein L22.

Q9VVX3	FRIZ2_DROME	Frizzled-2	8717036	A new member of the frizzled family from Drosophila functions as a Wingless receptor.

Q9P225	DYH2_HUMAN	Dynein heavy chain 2, axonemal	9256245	Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.

P22192	PAC1_SCHPO	Double-strand-specific pac1 ribonuclease	1989884	S. pombe pac1+, whose overexpression inhibits sexual development, encodes a ribonuclease III-like RNase.

O94663	SNF8_SCHPO	Vacuolar-sorting protein dot2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q03758	BUL2_YEAST	Ubiquitin ligase-binding protein BUL2	9931424	The PY-motif of Bul1 protein is essential for growth of Saccharomyces cerevisiae under various stress conditions.

Q13761	RUNX3_HUMAN	Runt-related transcription factor 3	7622058	Cloning, mapping and expression of PEBP2 alpha C, a third gene encoding the mammalian Runt domain.

P16220	CREB1_HUMAN	Cyclic AMP-responsive element-binding protein 1	16325578	A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription.

Q5JPE7	NOMO2_HUMAN	Nodal modulator 2	17261586	The Nicastrin-like protein Nicalin regulates assembly and stability of the Nicalin-nodal modulator (NOMO) membrane protein complex.

P32019	I5P2_HUMAN	Type II inositol-1,4,5-trisphosphate 5-phosphatase	7721860	Properties of type II inositol polyphosphate 5-phosphatase.

O35526	STX1A_MOUSE	Syntaxin-1A	18760330	Leucine-rich glioma inactivated 3 associates with syntaxin 1.

Q9LTR2	TGD2_ARATH	Protein TRIGALACTOSYLDIACYLGLYCEROL 2, chloroplastic	12938931	Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis.

P38325	OM14_YEAST	Mitochondrial outer membrane protein OM14	14562095	Global analysis of protein localization in budding yeast.

Q9SJ44	UEV1C_ARATH	Ubiquitin-conjugating enzyme E2 variant 1C	18178771	Arabidopsis UEV1D promotes lysine-63-linked polyubiquitination and is involved in DNA damage response.

O75197	LRP5_HUMAN	Low-density lipoprotein receptor-related protein 5	9714764	Cloning of a novel member of the low-density lipoprotein receptor family.

Q07500	NDH2_YEAST	External NADH-ubiquinone oxidoreductase 2, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

O60056	YG55_SCHPO	Uncharacterized transcriptional regulatory protein C56F2.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P48740	MASP1_HUMAN	Mannan-binding lectin serine protease 1	11907111	Activation of the lectin complement pathway by H-ficolin (Hakata antigen).

Q08949	DDC1_YEAST	DNA damage checkpoint protein 1	12604797	Yeast Rad17/Mec3/Ddc1: a sliding clamp for the DNA damage checkpoint.

P06241	FYN_HUMAN	Tyrosine-protein kinase Fyn	3526330	Yes-related protooncogene, syn, belongs to the protein-tyrosine kinase family.

Q8BYR5	CAPS2_MOUSE	Calcium-dependent secretion activator 2	12659812	Cloning and characterization of human CADPS and CADPS2, new members of the Ca2+-dependent activator for secretion protein family.

Q60857	SC6A4_MOUSE	Sodium-dependent serotonin transporter	17452640	Physical interaction between the serotonin transporter and neuronal nitric oxide synthase underlies reciprocal modulation of their activity.

Q7X9I4	ERO2_ARATH	Endoplasmic oxidoreductin-2	13678526	Cloning and initial characterization of the Arabidopsis thaliana endoplasmic reticulum oxidoreductins.

Q13485	SMAD4_HUMAN	Mothers against decapentaplegic homolog 4	8774881	Receptor-associated Mad homologues synergize as effectors of the TGF- beta response.

Q9UJA3	MCM8_HUMAN	DNA replication licensing factor MCM8	15684404	Involvement of human MCM8 in prereplication complex assembly by recruiting hcdc6 to chromatin.

O43060	EIF3F_SCHPO	Eukaryotic translation initiation factor 3 subunit F	15904532	PCI proteins eIF3e and eIF3m define distinct translation initiation factor 3 complexes.

Q12136	SAS10_YEAST	Something about silencing protein 10	12068309	A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis.

P39526	LAA1_YEAST	AP-1 accessory protein LAA1	16702403	Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes.

P20417	PTN1_RAT	Tyrosine-protein phosphatase non-receptor type 1	2154749	Cloning and expression of a protein-tyrosine-phosphatase.

O74735	ATX1_SCHPO	Metal homeostasis factor atx1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O93507	TAL1_DANRE	T-cell acute lymphocytic leukemia protein 1 homolog	9670018	The SCL gene specifies haemangioblast development from early mesoderm.

P47900	P2RY1_HUMAN	P2Y purinoceptor 1	9442040	Molecular basis for ADP-induced platelet activation. II. The P2Y1 receptor mediates ADP-induced intracellular calcium mobilization and shape change in platelets.

P19404	NDUV2_HUMAN	NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

Q00495	CSF1R_RAT	Macrophage colony-stimulating factor 1 receptor	1389227	Molecular cloning of CSF-1 receptor from rat myoblasts. Sequence analysis and regulation during myogenesis.

P01815	HV202_HUMAN	Ig heavy chain V-II region COR	5449120	The amino acid sequences of the Fd fragments of two human gamma-1 heavy chains.

P35240	MERL_HUMAN	Merlin	10401006	Novel alternatively spliced isoforms of the neurofibromatosis type 2 tumor suppressor are targeted to the nucleus and cytoplasmic granules.

P13686	PPA5_HUMAN	Tartrate-resistant acid phosphatase type 5	2338077	Type 5 acid phosphatase. Sequence, expression and chromosomal localization of a differentiation-associated protein of the human macrophage.

Q9HGP5	CAPZB_SCHPO	F-actin-capping protein subunit beta	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UBN6	TR10D_HUMAN	Tumor necrosis factor receptor superfamily member 10D	9430226	The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain.

P97299	SFRP2_MOUSE	Secreted frizzled-related protein 2	9096311	A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors.

O00555	CAC1A_HUMAN	Voltage-dependent P/Q-type calcium channel subunit alpha-1A	11865310	Differential modulation of Ca(v)2.1 channels by calmodulin and Ca2+- binding protein 1.

Q02825	SEN54_YEAST	tRNA-splicing endonuclease subunit SEN54	9200603	The yeast tRNA splicing endonuclease: a tetrameric enzyme with two active site subunits homologous to the archaeal tRNA endonucleases.

Q9BRQ8	AIFM2_HUMAN	Apoptosis-inducing factor 2	12135761	A novel p53-inducible apoptogenic gene, PRG3, encodes a homologue of the apoptosis-inducing factor (AIF).

Q8LE52	DHAR3_ARATH	Glutathione S-transferase DHAR3, chloroplastic	15352244	New targets of Arabidopsis thioredoxins revealed by proteomic analysis.

P36012	CENPA_YEAST	Histone H3-like centromeric protein CSE4	10958698	The N-terminus of the centromere H3-like protein Cse4p performs an essential function distinct from that of the histone fold domain.

Q9USK2	SET9_SCHPO	Histone-lysine N-methyltransferase set9	15550243	Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage.

Q9C6I4	G2OX7_ARATH	Gibberellin 2-beta-dioxygenase 7	12509528	Overexpression of a novel class of gibberellin 2-oxidases decreases gibberellin levels and creates dwarf plants.

Q7Z465	BNIPL_HUMAN	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein	12901880	BNIPL-2, a novel homologue of BNIP-2, interacts with Bcl-2 and Cdc42GAP in apoptosis.

Q8VI38	GBGT1_MOUSE	Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1	14573676	Forssman synthetase expression results in diminished shiga toxin susceptibility: a role for glycolipids in determining host-microbe interactions.

P27323	HSP81_ARATH	Heat shock protein 81-1	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

O94690	RM36_SCHPO	54S ribosomal protein c83.06c, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P83242	MSMB_STRCA	Beta-microseminoprotein	11604528	Characterization of ostrich (Struthio camelus) beta- microseminoprotein (MSP): identification of homologous sequences in EST databases and analysis of their evolution during speciation.

Q96K12	FACR2_HUMAN	Fatty acyl-CoA reductase 2	15220348	Mammalian wax biosynthesis: I. Identification of two fatty acyl- coenzyme A reductases with different substrate specificities and tissue distributions.

Q8IX03	KIBRA_HUMAN	Protein KIBRA	18190796	KIBRA interacts with discoidin domain receptor 1 to modulate collagen-induced signalling.

Q9VHP0	DDX3_DROME	ATP-dependent RNA helicase bel	16531407	Double-stranded RNA is internalized by scavenger receptor-mediated endocytosis in Drosophila S2 cells.

Q07108	CD69_HUMAN	Early activation antigen CD69	8340758	Molecular cloning, expression, and chromosomal localization of the human earliest lymphocyte activation antigen AIM/CD69, a new member of the C-type animal lectin superfamily of signal-transmitting receptors.

Q9ERI2	RB27A_MOUSE	Ras-related protein Rab-27A	10859366	A mutation in Rab27a causes the vesicle transport defects observed in ashen mice.

P09184	VSR_ECOLI	Very short patch repair protein	1944537	The vsr gene product of E. coli K-12 is a strand- and sequence- specific DNA mismatch endonuclease.

Q08952	OXR1_YEAST	Oxidation resistance protein 1	15060142	Stress induction and mitochondrial localization of Oxr1 proteins in yeast and humans.

O14745	NHRF1_HUMAN	Na(+)/H(+) exchange regulatory cofactor NHE-RF1	12471024	The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator- interacting PDZ proteins.

Q8C052	MAP1S_MOUSE	Microtubule-associated protein 1S	16297881	Microtubule-associated protein 8 contains two microtubule binding sites.

Q9V3P0	PRDX1_DROME	Peroxiredoxin 1	11877442	Thioredoxin-2 but not thioredoxin-1 is a substrate of thioredoxin peroxidase-1 from Drosophila melanogaster: isolation and characterization of a second thioredoxin in D.melanogaster and evidence for distinct biological functions of Trx-1 and Trx-2.

Q9GYU8	NUP88_DROME	Nuclear pore complex protein Nup88	10921908	members only encodes a Drosophila nucleoporin required for rel protein import and immune response activation.

P36938	PGM_ECOLI	Phosphoglucomutase	8083177	Molecular cloning and characterization of the pgm gene encoding phosphoglucomutase of Escherichia coli.

Q9ZVM9	Y1461_ARATH	Probable serine/threonine-protein kinase At1g54610	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q9M3D6	AB19G_ARATH	ABC transporter G family member 19	16116418	Overexpression of an Arabidopsis thaliana ABC transporter confers kanamycin resistance to transgenic plants.

P87231	MUS81_SCHPO	Crossover junction endonuclease mus81	12084712	Mus81-Eme1 and Rqh1 involvement in processing stalled and collapsed replication forks.

Q9R1J0	NSDHL_MOUSE	Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating	10369263	The gene mutated in bare patches and striated mice encodes a novel 3beta-hydroxysteroid dehydrogenase.

P84834	TY2_ASCTR	Tryptophyllin-2	15922344	Bradykinin-related peptides and tryptophyllins in the skin secretions of the most primitive extant frog, Ascaphus truei.

P34142	RAB21_DICDI	Ras-related protein Rab-21	15962002	A Rab21/LIM-only/CH-LIM complex regulates phagocytosis via both activating and inhibitory mechanisms.

Q9UST7	SFC3_SCHPO	Transcription factor tau subunit sfc3	16751097	A role for TFIIIC transcription factor complex in genome organization.

Q9VVI3	NEDD4_DROME	E3 ubiquitin-protein ligase Nedd-4	15620649	Drosophila Nedd4 regulates endocytosis of notch and suppresses its ligand-independent activation.

P82970	HMGN5_HUMAN	High mobility group nucleosome-binding domain-containing protein 5	11161810	Characterization of a human gene encoding nucleosomal binding protein NSBP1.

P39735	SAW1_YEAST	Single-strand annealing weakened protein 1	14562095	Global analysis of protein localization in budding yeast.

P54787	VPS9_YEAST	Vacuolar protein sorting-associated protein 9	8628304	A yeast protein related to a mammalian Ras-binding protein, Vps9p, is required for localization of vacuolar proteins.

P56470	LEG4_HUMAN	Galectin-4	9162064	Strikingly different localization of galectin-3 and galectin-4 in human colon adenocarcinoma T84 cells. Galectin-4 is localized at sites of cell adhesion.

P08235	MCR_HUMAN	Mineralocorticoid receptor	3037703	Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor.

Q10426	RIK1_SCHPO	Chromatin modification-related protein rik1	15372076	A chromodomain protein, Chp1, is required for the establishment of heterochromatin in fission yeast.

P42698	DR111_ARATH	DNA-damage-repair/toleration protein DRT111, chloroplastic	8479917	Two cDNAs from the plant Arabidopsis thaliana that partially restore recombination proficiency and DNA-damage resistance to E. coli mutants lacking recombination-intermediate-resolution activities.

O14610	GBGT2_HUMAN	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2	9286705	Gene structure and chromosome localization of the G gamma c subunit of human cone G-protein (GNGT2).

Q98867	THAA_DANRE	Thyroid hormone receptor alpha-A	9447705	The zebrafish thyroid hormone receptor alpha 1 is expressed during early embryogenesis and can function in transcriptional repression.

P50091	PEX21_YEAST	Peroxisomal membrane protein PEX21	9864360	Pex18p and Pex21p, a novel pair of related peroxins essential for peroxisomal targeting by the PTS2 pathway.

Q9JMB7	PIWL1_MOUSE	Piwi-like protein 1	16938833	MIWI associates with translational machinery and PIWI-interacting RNAs (piRNAs) in regulating spermatogenesis.

Q04472	MGR3_YEAST	Mitochondrial inner membrane i-AAA protease supercomplex subunit MGR3	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q9C115	REC25_SCHPO	Meiotic recombination protein rec25	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P31115	PUS3_YEAST	tRNA pseudouridine synthase 3	9430663	Characterization of yeast protein Deg1 as pseudouridine synthase (Pus3) catalyzing the formation of psi 38 and psi 39 in tRNA anticodon loop.

Q03201	RT10_YEAST	37S ribosomal protein S10, mitochondrial	11278769	Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues.

Q9SR37	BGL23_ARATH	Beta-glucosidase 23	20543027	The deubiquitinating enzyme AMSH3 is required for intracellular trafficking and vacuole biogenesis in Arabidopsis thaliana.

P46462	TERA_RAT	Transitional endoplasmic reticulum ATPase	7806566	Isolation and characterization of the principal ATPase associated with transitional endoplasmic reticulum of rat liver.

Q9JI10	STK3_MOUSE	Serine/threonine-protein kinase 3	20080689	Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver.

P36012	CENPA_YEAST	Histone H3-like centromeric protein CSE4	11063678	CSE4 genetically interacts with the Saccharomyces cerevisiae centromere DNA elements CDE I and CDE II but not CDE III. Implications for the path of the centromere dna around a cse4p variant nucleosome.

Q9JLA3	UGGG1_RAT	UDP-glucose:glycoprotein glucosyltransferase 1	11535823	Immunolocalization of UDP-glucose:glycoprotein glucosyltransferase indicates involvement of pre-Golgi intermediates in protein quality control.

Q9Y7R8	MDHM_SCHPO	Malate dehydrogenase, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q42342	CYB51_ARATH	Cytochrome b5 isoform 1	9880378	Microsomal electron transfer in higher plants: cloning and heterologous expression of NADH-cytochrome b5 reductase from Arabidopsis.

O95786	DDX58_HUMAN	Probable ATP-dependent RNA helicase DDX58	18243112	The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I.

P28328	PEX2_HUMAN	Peroxisome biogenesis factor 2	1546315	A human gene responsible for Zellweger syndrome that affects peroxisome assembly.

P33313	CNS1_YEAST	Hsp70/Hsp90 co-chaperone CNS1	9819422	Cns1 is an essential protein associated with the hsp90 chaperone complex in Saccharomyces cerevisiae that can restore cyclophilin 40- dependent functions in cpr7Delta cells.

Q94JM3	ARFB_ARATH	Auxin response factor 2	15960614	AUXIN RESPONSE FACTOR 2 (ARF2): a pleiotropic developmental regulator.

O14639	ABLM1_HUMAN	Actin-binding LIM protein 1	9245787	Molecular characterization of abLIM, a novel actin-binding and double zinc finger protein.

Q01532	BLH1_YEAST	Cysteine proteinase 1, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P19544	WT1_HUMAN	Wilms tumor protein	15518539	Why zinc fingers prefer zinc: ligand-field symmetry and the hidden thermodynamics of metal ion selectivity.

Q9UBC3	DNM3B_HUMAN	DNA (cytosine-5)-methyltransferase 3B	10325416	The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors.

Q9Y5P4	C43BP_HUMAN	Collagen type IV alpha-3-binding protein	17591919	Regulation of secretory transport by protein kinase D-mediated phosphorylation of the ceramide transfer protein.

O75398	DEAF1_HUMAN	Deformed epidermal autoregulatory factor 1 homolog	18826651	Deaf-1 regulates epithelial cell proliferation and side-branching in the mammary gland.

P41596	DOPR1_DROME	Dopamine receptor 1	17634358	D1 dopamine receptor dDA1 is required in the mushroom body neurons for aversive and appetitive learning in Drosophila.

Q06325	YPS7_YEAST	Aspartic proteinase yapsin-7	16087741	Yapsins are a family of aspartyl proteases required for cell wall integrity in Saccharomyces cerevisiae.

Q13258	PD2R_HUMAN	Prostaglandin D2 receptor	7642548	Molecular cloning and characterization of the human prostanoid DP receptor.

P90901	IFA1_CAEEL	Intermediate filament protein ifa-1	11427699	Essential roles for four cytoplasmic intermediate filament proteins in Caenorhabditis elegans development.

P54274	TERF1_HUMAN	Telomeric repeat-binding factor 1	7502076	A human telomeric protein.

Q9WUI0	MIXL1_MOUSE	Homeobox protein MIXL1	17151016	Sequential allocation and global pattern of movement of the definitive endoderm in the mouse embryo during gastrulation.

O73689	ZIC1_XENLA	Zinc finger protein ZIC 1	15843410	Neural crest determination by co-activation of Pax3 and Zic1 genes in Xenopus ectoderm.

Q13547	HDAC1_HUMAN	Histone deacetylase 1	19081374	A calcium-dependent switch in a CREST-BRG1 complex regulates activity-dependent gene expression.

Q62120	JAK2_MOUSE	Tyrosine-protein kinase JAK2	20304997	Tyrosines 868, 966, and 972 in the kinase domain of JAK2 are autophosphorylated and required for maximal JAK2 kinase activity.

Q9D3V5	FSIP1_MOUSE	Fibrous sheath-interacting protein 1	12606363	A-kinase anchoring protein 4 binding proteins in the fibrous sheath of the sperm flagellum.

P32657	CHD1_YEAST	Chromo domain-containing protein 1	15647753	Chd1 chromodomain links histone H3 methylation with SAGA- and SLIK- dependent acetylation.

P42826	XKS1_YEAST	Xylulose kinase	9595677	The YGR194c (XKS1) gene encodes the xylulokinase from the budding yeast Saccharomyces cerevisiae.

Q92925	SMRD2_HUMAN	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2	8804307	Diversity and specialization of mammalian SWI/SNF complexes.

P75804	YLII_ECOLI	Soluble aldose sugar dehydrogenase yliI	16864586	Soluble aldose sugar dehydrogenase from Escherichia coli: a highly exposed active site conferring broad substrate specificity.

P62158	CALM_HUMAN	Calmodulin	17719545	Cep97 and CP110 suppress a cilia assembly program.

P98175	RBM10_HUMAN	RNA-binding protein 10	18669648	A quantitative atlas of mitotic phosphorylation.

P21373	UTR1_YEAST	NAD(+) kinase	11425472	Molecular cloning and identification of UTR1 of a yeast Saccharomyces cerevisiae as a gene encoding an NAD kinase.

Q5MD89	VGFR3_DANRE	Vascular endothelial growth factor receptor 3	16617120	Distinct genetic interactions between multiple Vegf receptors are required for development of different blood vessel types in zebrafish.

Q9UHD4	CIDEB_HUMAN	Cell death activator CIDE-B	10619428	Solution structure of the CIDE-N domain of CIDE-B and a model for CIDE-N/CIDE-N interactions in the DNA fragmentation pathway of apoptosis.

P05106	ITB3_HUMAN	Integrin beta-3	2452834	Structure of platelet glycoprotein IIIa. A common subunit for two different membrane receptors.

P16284	PECA1_HUMAN	Platelet endothelial cell adhesion molecule	7994021	Organization of the gene for human platelet/endothelial cell adhesion molecule-1 shows alternatively spliced isoforms and a functionally complex cytoplasmic domain.

O35757	VEGFC_RAT	Vascular endothelial growth factor C	11683876	Characterization of indolinones which preferentially inhibit VEGF-C- and VEGF-D-induced activation of VEGFR-3 rather than VEGFR-2.

O60016	CLR4_SCHPO	Histone-lysine N-methyltransferase, H3 lysine-9 specific	16024659	A Rik1-associated, cullin-dependent E3 ubiquitin ligase is essential for heterochromatin formation.

Q13263	TIF1B_HUMAN	Transcription intermediary factor 1-beta	18060868	A novel GDNF-inducible gene, BMZF3, encodes a transcriptional repressor associated with KAP-1.

Q07351	STP4_YEAST	Zinc finger protein STP4	14562095	Global analysis of protein localization in budding yeast.

P58906	LECA_CANBN	Lectin alpha chain	10082964	Molecular characterization and crystallization of Diocleinae lectins.

P83305	JAP1_RANJA	Japonicin-1	11835990	Antimicrobial peptides with atypical structural features from the skin of the Japanese brown frog Rana japonica.

Q8K3Y6	ZCCHV_RAT	Zinc finger CCCH-type antiviral protein 1	12215647	Inhibition of retroviral RNA production by ZAP, a CCCH-type zinc finger protein.

Q92547	TOPB1_HUMAN	DNA topoisomerase 2-binding protein 1	20080954	A vertebrate gene, ticrr, is an essential checkpoint and replication regulator.

P38859	DNA2_YEAST	DNA replication ATP-dependent helicase DNA2	7644470	A yeast gene required for DNA replication encodes a protein with homology to DNA helicases.

O54942	CLD5_MOUSE	Claudin-5	9892664	Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands.

Q9C0U7	VPS5_SCHPO	Vacuolar protein sorting-associated protein vps5	16622069	Vacuolar protein sorting receptor in Schizosaccharomyces pombe.

P41411	CDC18_SCHPO	Cell division control protein 18	9653157	sud1+ targets cyclin-dependent kinase-phosphorylated Cdc18 and Rum1 proteins for degradation and stops unwanted diploidization in fission yeast.

Q12055	KAD6_YEAST	Putative adenylate kinase FAP7	12837249	A panoramic view of yeast noncoding RNA processing.

P82804	WIBG_DROME	Partner of Y14 and mago	14968132	Molecular insights into the interaction of PYM with the Mago-Y14 core of the exon junction complex.

Q9VR07	INE_DROME	Sodium- and chloride-dependent GABA transporter ine	11861562	The Drosophila inebriated-encoded neurotransmitter/osmolyte transporter: dual roles in the control of neuronal excitability and the osmotic stress response.

Q93XW5	NSP5_ARATH	Nitrile-specifier protein 5	18987211	The genetic basis of constitutive and herbivore-induced ESP- independent nitrile formation in Arabidopsis.

Q96J02	ITCH_HUMAN	E3 ubiquitin-protein ligase Itchy homolog	20392206	The ubiquitin ligase Itch mediates the antiapoptotic activity of epidermal growth factor by promoting the ubiquitylation and degradation of the truncated C-terminal portion of Bid.

P06634	DED1_YEAST	ATP-dependent RNA helicase DED1	14763975	Dynamics and processivity of 40S ribosome scanning on mRNA in yeast.

O76096	CYTF_HUMAN	Cystatin-F	9632704	Leukocystatin, a new class II cystatin expressed selectively by hematopoietic cells.

Q15596	NCOA2_HUMAN	Nuclear receptor coactivator 2	8670870	TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors.

Q92633	LPAR1_HUMAN	Lysophosphatidic acid receptor 1	19306925	Dual regulation of lysophosphatidic acid (LPA1) receptor signalling by Ral and GRK.

Q8NEP3	LRC50_HUMAN	Leucine-rich repeat-containing protein 50	19944400	Deletions and point mutations of LRRC50 cause primary ciliary dyskinesia due to dynein arm defects.

P38790	HTD2_YEAST	Hydroxyacyl-thioester dehydratase type 2, mitochondrial	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

P91001	CSN5_CAEEL	COP9 signalosome complex subunit 5	12781129	Neddylation and deneddylation of CUL-3 is required to target MEI- 1/katanin for degradation at the meiosis-to-mitosis transition in C. elegans.

P54660	PONA_DICDI	Ponticulin	18522444	Minimal F-actin cytoskeletal system for planar supported phospholipid bilayers.

Q9NZP6	CO002_HUMAN	Protein C15orf2	10783265	Identification of a testis-specific gene (c15orf2) in the Prader- Willi syndrome region on chromosome 15.

O13826	RFP1_SCHPO	E3 ubiquitin-protein ligase complex slx8-rfp subunit rfp1	17502373	Fission yeast Rnf4 homologs are required for DNA repair.

O70257	STX7_RAT	Syntaxin-7	15133481	Combinatorial SNARE complexes with VAMP7 or VAMP8 define different late endocytic fusion events.

Q9FKZ3	LBD36_ARATH	LOB domain-containing protein 36	12787254	Activation tagging, a novel tool to dissect the functions of a gene family.

Q02775	SLU7_YEAST	Pre-mRNA-splicing factor SLU7	12212850	How Slu7 and Prp18 cooperate in the second step of yeast pre-mRNA splicing.

P04035	HMDH_HUMAN	3-hydroxy-3-methylglutaryl-coenzyme A reductase	10698924	Crystal structure of the catalytic portion of human HMG-CoA reductase: insights into regulation of activity and catalysis.

Q8STE5	CED12_CAEEL	Cell death abnormality protein 12	11146658	A common set of engulfment genes mediates removal of both apoptotic and necrotic cell corpses in C. elegans.

P25070	CML24_ARATH	Calcium-binding protein CML24	16113225	CML24, regulated in expression by diverse stimuli, encodes a potential Ca2+ sensor that functions in responses to abscisic acid, daylength, and ion stress.

Q9LFJ8	UGFGT_ARATH	Flavonoid 3-O-glucosyltransferase	15807784	Functional genomics by integrated analysis of metabolome and transcriptome of Arabidopsis plants over-expressing an MYB transcription factor.

Q9I9K7	TBX20_DANRE	T-box transcription factor TBX20	10656766	A conserved role for H15-related T-box transcription factors in zebrafish and Drosophila heart formation.

Q9USH6	YJQ4_SCHPO	Uncharacterized N-acetyltransferase C825.04c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q06251	YL177_YEAST	Uncharacterized protein YLR177W	14562095	Global analysis of protein localization in budding yeast.

P53214	MTL1_YEAST	Protein MTL1	10330137	Mid2 is a putative sensor for cell integrity signaling in Saccharomyces cerevisiae.

Q9UNK4	PA2GD_HUMAN	Group IID secretory phospholipase A2	10455175	Cloning and characterization of novel mouse and human secretory phospholipase A2s.

P52285	SKP1A_DICDI	SCF ubiquitin ligase complex protein SKP1a	11358877	Analysis of Skp1 glycosylation and nuclear enrichment in Dictyostelium.

Q13639	5HT4R_HUMAN	5-hydroxytryptamine receptor 4	9351641	Cloning and expression of human 5-HT4S receptors. Effect of receptor density on their coupling to adenylyl cyclase.

P48725	PCNT_MOUSE	Pericentrin	8124707	Pericentrin, a highly conserved centrosome protein involved in microtubule organization.

P49366	DHYS_HUMAN	Deoxyhypusine synthase	8549832	Molecular characterization of a cDNA encoding functional human deoxyhypusine synthase and chromosomal mapping of the corresponding gene locus.

P49177	GBB_ARATH	Guanine nucleotide-binding protein subunit beta	18223036	Characterization of Arabidopsis and rice DWD proteins and their roles as substrate receptors for CUL4-RING E3 ubiquitin ligases.

Q9P7F3	AMT3_SCHPO	Ammonium transporter 3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q13467	FZD5_HUMAN	Frizzled-5	9054360	A member of the Frizzled protein family mediating axis induction by Wnt-5A.

Q8IWV1	LAX1_HUMAN	Lymphocyte transmembrane adapter 1	12359715	Molecular cloning of a novel gene encoding a membrane-associated adaptor protein (LAX) in lymphocyte signaling.

Q62392	PHLA1_MOUSE	Pleckstrin homology-like domain family A member 1	8673705	A novel gene product that couples TCR signaling to Fas(CD95) expression in activation-induced cell death.

Q9DCD6	GBRAP_MOUSE	Gamma-aminobutyric acid receptor-associated protein	10899939	Binding of the GABA(A) receptor-associated protein (GABARAP) to microtubules and microfilaments suggests involvement of the cytoskeleton in GABARAPGABA(A) receptor interaction.

P01106	MYC_HUMAN	Myc proto-oncogene protein	20551172	Myc protein is stabilized by suppression of a novel E3 ligase complex in cancer cells.

Q96LB9	PGRP3_HUMAN	Peptidoglycan recognition protein 3	11461926	Peptidoglycan recognition proteins: a novel family of four human innate immunity pattern recognition molecules.

Q25QX6	BOWL_XENLA	Protein bowline	17577580	Bowline mediates association of the transcriptional corepressor XGrg- 4 with Tbx6 during somitogenesis in Xenopus.

Q13268	DHRS2_HUMAN	Dehydrogenase/reductase SDR family member 2	16685466	Hep27, a member of the short-chain dehydrogenase/reductase family, is an NADPH-dependent dicarbonyl reductase expressed in vascular endothelial tissue.

Q08831	VTS1_YEAST	Protein VTS1	11445562	Genetic interactions with the yeast Q-SNARE VTI1 reveal novel functions for the R-SNARE YKT6.

Q922W5	P5CR1_MOUSE	Pyrroline-5-carboxylate reductase 1, mitochondrial	14651853	Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.

P15151	PVR_HUMAN	Poliovirus receptor	15034010	CD96 (tactile) promotes NK cell-target cell adhesion by interacting with the poliovirus receptor (CD155).

Q08215	PEX15_YEAST	Peroxisomal membrane protein PEX15	9405362	Overexpression of Pex15p, a phosphorylated peroxisomal integral membrane protein required for peroxisome assembly in S.cerevisiae, causes proliferation of the endoplasmic reticulum membrane.

Q08378	GOGA3_HUMAN	Golgin subfamily A member 3	8315394	Molecular characterization of two human autoantigens: unique cDNAs encoding 95- and 160-kD proteins of a putative family in the Golgi complex.

O43615	TIM44_HUMAN	Mitochondrial import inner membrane translocase subunit TIM44	10339406	Genetic and structural characterization of the human mitochondrial inner membrane translocase.

Q14524	SCN5A_HUMAN	Sodium channel protein type 5 subunit alpha	7651517	Molecular mechanism for an inherited cardiac arrhythmia.

P27812	KRBBA_MOUSE	Killer cell lectin-like receptor subfamily B member 1B allele A	14990792	Missing self-recognition of Ocil/Clr-b by inhibitory NKR-P1 natural killer cell receptors.

Q9S9K9	MYB3_ARATH	Transcription factor MYB3	18541146	The C-terminal region (640-967) of Arabidopsis CPL1 interacts with the abiotic stress- and ABA-responsive transcription factors.

O13996	YEI1_SCHPO	Uncharacterized glycosyl hydrolase C27E2.01	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P49166	RL37A_YEAST	60S ribosomal protein L37-A	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q10589	BST2_HUMAN	Bone marrow stromal antigen 2	7607676	Molecular cloning and chromosomal mapping of a bone marrow stromal cell surface gene, BST2, that may be involved in pre-B-cell growth.

P47069	MPS3_YEAST	Spindle pole body assembly component MPS3	12486115	Mps3p is a novel component of the yeast spindle pole body that interacts with the yeast centrin homologue Cdc31p.

O23166	TR164_ARATH	Thioredoxin-like protein HCF164, chloroplastic	11701887	HCF164 encodes a thioredoxin-like protein involved in the biogenesis of the cytochrome b(6)f complex in Arabidopsis.

P47869	GBRA2_HUMAN	Gamma-aminobutyric acid receptor subunit alpha-2	8391122	Cloning of cDNA sequences encoding human alpha 2 and alpha 3 gamma- aminobutyric acidA receptor subunits and characterization of the benzodiazepine pharmacology of recombinant alpha 1-, alpha 2-, alpha 3-, and alpha 5-containing human gamma-aminobutyric acidA receptors.

Q8QZW2	FEV_MOUSE	Protein FEV	11875656	mPet-1, a mouse ETS-domain transcription factor, is expressed in central serotonergic neurons.

P27814	KLRBC_MOUSE	Killer cell lectin-like receptor subfamily B member 1C	1506685	Molecular cloning of the NK1.1 antigen, a member of the NKR-P1 family of natural killer cell activation molecules.

Q8TBF4	ZCRB1_HUMAN	Zinc finger CCHC-type and RNA-binding motif-containing protein 1	15146077	The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome.

P53718	NRM1_YEAST	Transcription factor NRM1	16916637	Constraining G1-specific transcription to late G1 phase: the MBF- associated corepressor Nrm1 acts via negative feedback.

P38840	ARO9_YEAST	Aromatic amino acid aminotransferase 2	9491083	Characterisation of Saccharomyces cerevisiae ARO8 and ARO9 genes encoding aromatic aminotransferases I and II reveals a new aminotransferase subfamily.

Q01664	TFAP4_HUMAN	Transcription factor AP-4	7933101	Role of flanking E box motifs in human immunodeficiency virus type 1 TATA element function.

P40161	RT106_YEAST	Histone chaperone RTT106	11779788	Multiple regulators of Ty1 transposition in Saccharomyces cerevisiae have conserved roles in genome maintenance.

Q93063	EXT2_HUMAN	Exostosin-2	9326317	Mutation screening of the EXT1 and EXT2 genes in patients with hereditary multiple exostoses.

O75078	ADA11_HUMAN	Disintegrin and metalloproteinase domain-containing protein 11	9693107	Metalloproteinase-like, disintegrin-like, cysteine-rich proteins MDC2 and MDC3: novel human cellular disintegrins highly expressed in the brain.

P12644	BMP4_HUMAN	Bone morphogenetic protein 4	18305125	SIX2 and BMP4 mutations associate with anomalous kidney development.

O95633	FSTL3_HUMAN	Follistatin-related protein 3	15451575	FLRG, member of the follistatin family, a new player in hematopoiesis.

P06783	STE3_YEAST	Pheromone a factor receptor	3006051	Evidence the yeast STE3 gene encodes a receptor for the peptide pheromone a factor: gene sequence and implications for the structure of the presumed receptor.

Q17391	CUL3_CAEEL	Cullin-3	13679922	BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3.

Q9P3V8	YI71_SCHPO	Uncharacterized membrane protein C977.01/C1348.02/PB2B2.19c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q39026	MPK6_ARATH	Mitogen-activated protein kinase 6	11875555	MAP kinase signalling cascade in Arabidopsis innate immunity.

P14954	CECA_DROME	Cecropin-A1/A2	2104802	The cecropin locus in Drosophila; a compact gene cluster involved in the response to infection.

Q99717	SMAD5_HUMAN	Mothers against decapentaplegic homolog 5	15647271	The integral inner nuclear membrane protein MAN1 physically interacts with the R-Smad proteins to repress signaling by the transforming growth factor-{beta} superfamily of cytokines.

Q14995	NR1D2_HUMAN	Nuclear receptor subfamily 1 group D member 2	7997240	A new orphan member of the nuclear hormone receptor superfamily closely related to Rev-Erb.

O43280	TREA_HUMAN	Trehalase	8773341	Human trehalase: characterization, localization, and its increase in urine by renal proximal tubular damage.

P38959	VPS41_YEAST	Vacuolar protein sorting-associated protein 41	16601699	Purification of active HOPS complex reveals its affinities for phosphoinositides and the SNARE Vam7p.

Q9Y696	CLIC4_HUMAN	Chloride intracellular channel protein 4	12163372	Differential expression of a chloride intracellular channel gene, CLIC4, in transforming growth factor-beta1-mediated conversion of fibroblasts to myofibroblasts.

P06239	LCK_HUMAN	Tyrosine-protein kinase Lck	7504174	The SH3 domain of p56lck is involved in binding to phosphatidylinositol 3'-kinase from T lymphocytes.

P40200	TACT_HUMAN	T-cell surface protein tactile	1313846	Identification and molecular cloning of tactile. A novel human T cell activation antigen that is a member of the Ig gene superfamily.

O14317	RLA6_SCHPO	60S acidic ribosomal protein P2-C	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P13611	CSPG2_HUMAN	Versican core protein	2583089	Multiple domains of the large fibroblast proteoglycan, versican.

P26782	RS24_YEAST	40S ribosomal protein S24	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q8I4R2	RBP3_PLAF7	Reticulocyte-binding protein 3	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

P17026	ZNF22_HUMAN	Zinc finger protein 22	14630903	The human KROX-26/ZNF22 gene is expressed at sites of tooth formation and maps to the locus for permanent tooth agenesis (He-Zhao deficiency).

P01711	LV208_HUMAN	Ig lambda chain V-II region VIL	5087637	Structural rule of antibodies. Complete primary structure of a monoclonal immunoglobin L chain of the lambda type, subgroup II (Bence Jones protein VIL).

Q9P787	YNY3_SCHPO	UPF0347 membrane protein C1711.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q06830	PRDX1_HUMAN	Peroxiredoxin-1	11986303	Regulation of peroxiredoxin I activity by Cdc2-mediated phosphorylation.

Q9H0M0	WWP1_HUMAN	NEDD4-like E3 ubiquitin-protein ligase WWP1	12450395	Adenovirus protein involved in virus internalization recruits ubiquitin-protein ligases.

P25385	BOS1_YEAST	Protein transport protein BOS1	11001058	Topological restriction of SNARE-dependent membrane fusion.

Q9XG81	PLA22_ORYSJ	Probable phospholipase A2 homolog 2	19457861	Crystal structure of a class XIB phospholipase A2 (PLA2): rice (oryza sativa) isoform-2 pla2 and an octanoate complex.

Q17389	CUL1_CAEEL	Cullin-1	8681378	cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family.

P54622	SSBP_DROME	Single-stranded DNA-binding protein, mitochondrial	7673145	Mitochondrial single-stranded DNA-binding protein from Drosophila embryos. Physical and biochemical characterization.

P70539	ACV1C_RAT	Activin receptor type-1C	8940033	A novel type I receptor serine-threonine kinase predominantly expressed in the adult central nervous system.

P32657	CHD1_YEAST	Chromo domain-containing protein 1	17949749	Histone modifications influence the action of Snf2 family remodelling enzymes by different mechanisms.

P29674	LHX1_XENLA	LIM/homeobox protein Lhx1	9023353	Role of the Xlim-1 and Xbra genes in anteroposterior patterning of neural tissue by the head and trunk organizer.

Q8K1P7	SMCA4_RAT	Transcription activator BRG1	19081374	A calcium-dependent switch in a CREST-BRG1 complex regulates activity-dependent gene expression.

P40574	YAP5_YEAST	AP-1-like transcription factor YAP5	9372930	Yap, a novel family of eight bZIP proteins in Saccharomyces cerevisiae with distinct biological functions.

Q9ULX6	AKP8L_HUMAN	A-kinase anchor protein 8-like	16391387	Interaction of the nuclear matrix protein NAKAP with HypA and huntingtin: implications for nuclear toxicity in Huntington's disease pathogenesis.

Q94B38	GPT2_ARATH	Glucose-6-phosphate/phosphate translocator 2, chloroplastic	15722468	The Arabidopsis plastidic glucose 6-phosphate/phosphate translocator GPT1 is essential for pollen maturation and embryo sac development.

P51151	RAB9A_HUMAN	Ras-related protein Rab-9A	9126495	Cloning and mapping of human Rab7 and Rab9 cDNA sequences and identification of a Rab9 pseudogene.

Q5R2I8	APCD1_CHICK	Protein APCDD1	20393562	APCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplex.

Q56ZN6	AVP2_ARATH	Pyrophosphate-energized membrane proton pump 2	15215502	Isolation of intact vacuoles and proteomic analysis of tonoplast from suspension-cultured cells of Arabidopsis thaliana.

O96033	MOC2A_HUMAN	Molybdopterin synthase sulfur carrier subunit	9889283	The two subunits of human molybdopterin synthase: evidence for a bicistronic messenger RNA with overlapping reading frames.

Q8NJJ1	MTLD_ASPNG	Mannitol-1-phosphate 5-dehydrogenase	12912888	Mannitol is required for stress tolerance in Aspergillus niger conidiospores.

Q6TMK2	SIGF_DICDI	SrfA-induced gene F protein	17517120	STATc is a key regulator of the transcriptional response to hyperosmotic shock.

Q8JI10	DMX1A_DANRE	Diencephalon/mesencephalon homeobox protein 1-A	12142024	The homeobox gene mbx is involved in eye and tectum development.

P40984	UBC9_SCHPO	SUMO-conjugating enzyme ubc9	7768995	The Schizosaccharomyces pombe hus5 gene encodes a ubiquitin conjugating enzyme required for normal mitosis.

O43291	SPIT2_HUMAN	Kunitz-type protease inhibitor 2	9115294	Identification and cloning of human placental bikunin, a novel serine protease inhibitor containing two Kunitz domains.

Q6GUQ1	EGFL8_MOUSE	Epidermal growth factor-like protein 8	15162510	Egfl7, a novel epidermal growth factor-domain gene expressed in endothelial cells.

O13701	TAF7_SCHPO	Transcription initiation factor TFIID subunit 7	10388808	Characterization of the ptr6(+) gene in fission yeast: a possible involvement of a transcriptional coactivator TAF in nucleocytoplasmic transport of mRNA.

P98064	MASP1_MOUSE	Mannan-binding lectin serine protease 1	18424734	Mannose-binding lectin (MBL)-associated serine protease (MASP)-1 contributes to activation of the lectin complement pathway.

Q8ISB6	BGBP2_MANSE	Beta-1,3-glucan-binding protein 2	14976985	Beta-1,3-glucan recognition protein-2 (betaGRP-2) from Manduca sexta: an acute-phase protein that binds beta-1,3-glucan and lipoteichoic acid to aggregate fungi and bacteria and stimulate prophenoloxidase activation.

P46597	HIOM_HUMAN	Hydroxyindole O-methyltransferase	7989373	Structural analysis of the human hydroxyindole-O-methyltransferase gene. Presence of two distinct promoters.

Q92570	NR4A3_HUMAN	Nuclear receptor subfamily 4 group A member 3	8570200	Fusion of the EWS gene to CHN, a member of the steroid/thyroid receptor gene superfamily, in a human myxoid chondrosarcoma.

Q96RE7	NACC1_HUMAN	Nucleus accumbens-associated protein 1	17391728	Expression and clinical role of the bric-a-brac tramtrack broad complex/poxvirus and zinc protein NAC-1 in ovarian carcinoma effusions.

Q8R015	MUTED_MOUSE	Protein Muted	11912185	The gene for the muted (mu) mouse, a model for Hermansky-Pudlak syndrome, defines a novel protein which regulates vesicle trafficking.

P40429	RL13A_HUMAN	60S ribosomal protein L13a	10580157	Gene organization and sequence of the region containing the ribosomal protein genes RPL13A and RPS11 in the human genome and conserved features in the mouse genome.

P41279	M3K8_HUMAN	Mitogen-activated protein kinase kinase kinase 8	8226782	The human cot proto-oncogene encodes two protein serine/threonine kinases with different transforming activities by alternative initiation of translation.

P31947	1433S_HUMAN	14-3-3 protein sigma	8515476	Molecular cloning and expression of the transformation sensitive epithelial marker stratifin. A member of a protein family that has been involved in the protein kinase C signalling pathway.

P32521	PAN1_YEAST	Actin cytoskeleton-regulatory complex protein PAN1	9531549	Pan1p, yeast eps15, functions as a multivalent adaptor that coordinates protein-protein interactions essential for endocytosis.

Q9ZZX0	AI5B_YEAST	Intron-encoded DNA endonuclease aI5 beta	9872396	The complete sequence of the mitochondrial genome of Saccharomyces cerevisiae.

Q09181	DHH1_SCHPO	Putative ATP-dependent RNA helicase ste13	8078473	The ste13+ gene encoding a putative RNA helicase is essential for nitrogen starvation-induced G1 arrest and initiation of sexual development in the fission yeast Schizosaccharomyces pombe.

Q9VKA5	GR33A_DROME	Putative gustatory receptor 33a	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

P04551	CDK1_SCHPO	Cell division control protein 2	16390871	Activity of Cdc2 and its interaction with the cyclin Cdc13 depend on the molecular chaperone Cdc37 in Schizosaccharomyces pombe.

Q9NPI1	BRD7_HUMAN	Bromodomain-containing protein 7	12489984	Regulation of transcription by the heterogeneous nuclear ribonucleoprotein E1B-AP5 is mediated by complex formation with the novel bromodomain-containing protein BRD7.

P32908	SMC1_YEAST	Structural maintenance of chromosomes protein 1	11983169	Molecular architecture of SMC proteins and the yeast cohesin complex.

Q12433	AHC1_YEAST	Protein AHC1	10490601	The ADA complex is a distinct histone acetyltransferase complex in Saccharomyces cerevisiae.

O75094	SLIT3_HUMAN	Slit homolog 3 protein	9813312	Cloning and expressions of three mammalian homologues of Drosophila slit suggest possible roles for Slit in the formation and maintenance of the nervous system.

Q8WU17	RN139_HUMAN	E3 ubiquitin-protein ligase RNF139	12032852	The TRC8 hereditary kidney cancer gene suppresses growth and functions with VHL in a common pathway.

O23680	TOC33_ARATH	Translocase of chloroplast 33, chloroplastic	10998188	Functional analysis of the two Arabidopsis homologues of Toc34, a component of the chloroplast protein import apparatus.

P48002	KNAT5_ARATH	Homeobox protein knotted-1-like 5	17873098	The Arabidopsis BEL1-LIKE HOMEODOMAIN proteins SAW1 and SAW2 act redundantly to regulate KNOX expression spatially in leaf margins.

Q8WX93	PALLD_HUMAN	Palladin	11598191	Characterization of human palladin, a microfilament-associated protein.

Q95ST2	WLS_DROME	Protein wntless	18160348	The retromer complex influences Wnt secretion by recycling wntless from endosomes to the trans-Golgi network.

P24806	XTH24_ARATH	Xyloglucan endotransglucosylase/hydrolase protein 24	11889033	The ANGUSTIFOLIA gene of Arabidopsis, a plant CtBP gene, regulates leaf-cell expansion, the arrangement of cortical microtubules in leaf cells and expression of a gene involved in cell-wall formation.

Q9LUL4	SRF7_ARATH	Protein STRUBBELIG-RECEPTOR FAMILY 7	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

P08263	GSTA1_HUMAN	Glutathione S-transferase A1	3800996	Human liver glutathione S-transferases: complete primary sequence of an Ha subunit cDNA.

Q7TN40	MRGRE_RAT	Mas-related G-protein coupled receptor member E	12909716	Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family.

O14008	CAM2_SCHPO	Myosin 1 light chain cam2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q09838	PRZ1_SCHPO	Transcriptional regulator prz1	12637524	Zinc finger protein Prz1 regulates Ca2+ but not Cl- homeostasis in fission yeast. Identification of distinct branches of calcineurin signaling pathway in fission yeast.

Q9BRA2	TXD17_HUMAN	Thioredoxin domain-containing protein 17	14607844	Identification and characterization of TRP14, a thioredoxin-related protein of 14 kDa. New insights into the specificity of thioredoxin function.

Q3E754	RS21B_YEAST	40S ribosomal protein S21-B	14627813	Ribosomal proteins Rps0 and Rps21 of Saccharomyces cerevisiae have overlapping functions in the maturation of the 3' end of 18S rRNA.

Q92913	FGF13_HUMAN	Fibroblast growth factor 13	8790420	Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development.

Q9YGL1	SPD1B_XENLA	Speedy protein 1-B	10202150	Speedy: a novel cell cycle regulator of the G2/M transition.

P52736	ZN133_HUMAN	Zinc finger protein 133	7557990	Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders.

Q12502	LDB19_YEAST	Protein LDB19	14562095	Global analysis of protein localization in budding yeast.

P10109	ADX_HUMAN	Adrenodoxin, mitochondrial	2969697	Molecular cloning and sequence analysis of human placental ferredoxin.

P32468	CDC12_YEAST	Cell division control protein 12	12665577	Molecular dissection of a yeast septin: distinct domains are required for septin interaction, localization, and function.

P52194	CLGN_MOUSE	Calmegin	8126001	Molecular cloning of a novel Ca(2+)-binding protein (calmegin) specifically expressed during male meiotic germ cell development.

Q9UTM2	CO111_SCHPO	Rsm22-cox11 tandem protein 1, mitochondrial	16835444	Sequential processing of a mitochondrial tandem protein: insights into protein import in Schizosaccharomyces pombe.

P92973	CCA1_ARATH	Protein CCA1	9724822	Protein kinase CK2 interacts with and phosphorylates the Arabidopsis circadian clock-associated 1 protein.

Q9LKW9	NHX7_ARATH	Sodium/hydrogen exchanger 7	12938931	Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis.

Q7Z434	MAVS_HUMAN	Mitochondrial antiviral-signaling protein	19881509	PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4.

O14263	YFP8_SCHPO	Uncharacterized protein C7D4.08	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q3U487	HECD3_MOUSE	E3 ubiquitin-protein ligase HECTD3	18821010	Interaction between syntaxin 8 and HECTd3, a HECT domain ligase.

O09028	GBRP_RAT	Gamma-aminobutyric acid receptor subunit pi	9182563	A novel class of GABAA receptor subunit in tissues of the reproductive system.

Q91XR9	GPX42_MOUSE	Phospholipid hydroperoxide glutathione peroxidase, nuclear	12566075	The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults.

Q92466	DDB2_HUMAN	DNA damage-binding protein 2	8798680	Mutations specific to the xeroderma pigmentosum group E Ddb- phenotype.

P12821	ACE_HUMAN	Angiotensin-converting enzyme	12540854	Crystal structure of the human angiotensin-converting enzyme- lisinopril complex.

P14373	TRI27_HUMAN	Zinc finger protein RFP	10976108	RET finger protein is a transcriptional repressor and interacts with enhancer of polycomb that has dual transcriptional functions.

Q9UJ68	MSRA_HUMAN	Peptide methionine sulfoxide reductase	10452521	Molecular cloning and functional expression of a human peptide methionine sulfoxide reductase (hMsrA).

O59790	ARK1_SCHPO	Serine/threonine-protein kinase ark1	11792803	The S. pombe aurora-related kinase Ark1 associates with mitotic structures in a stage dependent manner and is required for chromosome segregation.

P53251	SLX9_YEAST	Ribosome biogenesis protein SLX9	14562095	Global analysis of protein localization in budding yeast.

Q8C052	MAP1S_MOUSE	Microtubule-associated protein 1S	15528209	Microtubule-associated protein 1S, a short and ubiquitously expressed member of the microtubule-associated protein 1 family.

Q10113	MAL3_SCHPO	Microtubule integrity protein mal3	15177031	Tea2p kinesin is involved in spatial microtubule organization by transporting tip1p on microtubules.

Q15910	EZH2_HUMAN	Histone-lysine N-methyltransferase EZH2	16357870	The Polycomb group protein EZH2 directly controls DNA methylation.

Q9LRZ6	MYRS2_ARATH	Myrcene/ocimene synthase 2, chloroplastic	12566586	Biosynthesis and emission of terpenoid volatiles from Arabidopsis flowers.

P11161	EGR2_HUMAN	Early growth response protein 2	9537424	Mutations in the early growth response 2 (EGR2) gene are associated with hereditary myelinopathies.

P04803	SYWM_YEAST	Tryptophanyl-tRNA synthetase, mitochondrial	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

P53610	PGTB1_RAT	Geranylgeranyl transferase type-1 subunit beta	8106351	cDNA cloning and expression of rat and human protein geranylgeranyltransferase type-I.

Q8VZB2	PAS2_ARATH	3-hydroxyacyl-CoA dehydratase PASTICCINO 2	18799749	The very-long-chain hydroxy fatty acyl-CoA dehydratase PASTICCINO2 is essential and limiting for plant development.

Q6ZQF0	TOPB1_MOUSE	DNA topoisomerase 2-binding protein 1	14718568	TopBP1 and ATR colocalization at meiotic chromosomes: role of TopBP1/Cut5 in the meiotic recombination checkpoint.

Q3E7B2	YJ062_YEAST	Mitochondrial membrane protein YJL062W-A	14562095	Global analysis of protein localization in budding yeast.

P27633	TBP_XENLA	TATA-box-binding protein	17703192	TBP paralogs accommodate metazoan- and vertebrate-specific developmental gene regulation.

Q9UKT4	FBX5_HUMAN	F-box only protein 5	15469984	Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC inhibitor Emi1.

O14001	PVG2_SCHPO	Pyruvylated Gal-beta-1,3-epitope synthesis protein 2	15173185	Five genes involved in biosynthesis of the pyruvylated Galbeta1,3- epitope in Schizosaccharomyces pombe N-linked glycans.

Q15067	ACOX1_HUMAN	Peroxisomal acyl-coenzyme A oxidase 1	8117268	Molecular cloning and functional expression of a human peroxisomal acyl-coenzyme A oxidase.

Q56YA5	SGAT_ARATH	Serine--glyoxylate aminotransferase	11309139	Peroxisomal alanine:glyoxylate aminotransferase (AGT1) is a photorespiratory enzyme with multiple substrates in Arabidopsis thaliana.

Q9NPC1	LT4R2_HUMAN	Leukotriene B4 receptor 2	10889186	Molecular cloning and characterization of another leukotriene B4 receptor.

O43825	B3GT2_HUMAN	Beta-1,3-galactosyltransferase 2	9417100	Cloning of a human UDP-galactose:2-acetamido-2-deoxy-D-glucose 3beta- galactosyltransferase catalyzing the formation of type 1 chains.

P82998	GSTE_PSEP1	Glutathione S-transferase	11900268	Occurence and properties of glutathione S-transferases in phenol- degrading Pseudomonas strains.

Q60848	HELLS_MOUSE	Lymphocyte-specific helicase	11325543	Lsh, a SNF2 family member, is required for normal murine development.

Q99653	CHP1_HUMAN	Calcium-binding protein p22	8901634	A calcineurin homologous protein inhibits GTPase-stimulated Na-H exchange.

O75879	GATB_HUMAN	Probable glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial	9878253	Identification and characterization of human cDNAs specific to BCS1, PET112, SCO1, COX15, and COX11, five genes involved in the formation and function of the mitochondrial respiratory chain.

Q9UKY1	ZHX1_HUMAN	Zinc fingers and homeoboxes protein 1	10571058	Identification of proteins that interact with NF-YA.

Q570C0	TIR1_ARATH	Protein TRANSPORT INHIBITOR RESPONSE 1	9436980	The TIR1 protein of Arabidopsis functions in auxin response and is related to human SKP2 and yeast grr1p.

P29674	LHX1_XENLA	LIM/homeobox protein Lhx1	12874135	Selective degradation of excess Ldb1 by Rnf12/RLIM confers proper Ldb1 expression levels and Xlim-1/Ldb1 stoichiometry in Xenopus organizer functions.

Q6Q560	ISD11_YEAST	Protein ISD11	14562095	Global analysis of protein localization in budding yeast.

O00754	MA2B1_HUMAN	Lysosomal alpha-mannosidase	8910458	Cloning, expression, purification, and characterization of the human broad specificity lysosomal acid alpha-mannosidase.

P49427	UB2R1_HUMAN	Ubiquitin-conjugating enzyme E2 R1	20061386	The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.

P40958	MAD2_YEAST	Mitotic spindle checkpoint component MAD2	15879521	Two complexes of spindle checkpoint proteins containing Cdc20 and Mad2 assemble during mitosis independently of the kinetochore in Saccharomyces cerevisiae.

P59015	VPS18_DANRE	Vacuolar protein sorting-associated protein 18 homolog	16000385	A genetic screen in zebrafish identifies the mutants vps18, nf2 and foie gras as models of liver disease.

Q925F2	ESAM_MOUSE	Endothelial cell-selective adhesion molecule	11847224	A transmembrane tight junction protein selectively expressed on endothelial cells and platelets.

Q7XUW5	HS232_ORYSJ	23.2 kDa heat shock protein	19703271	Rice sHsp genes: genomic organization and expression profiling under stress and development.

P35325	SPR2B_HUMAN	Small proline-rich protein 2B	8325635	Molecular characterization and evolution of the SPRR family of keratinocyte differentiation markers encoding small proline-rich proteins.

P23348	B3A3_RAT	Anion exchange protein 3	2294114	cDNA cloning and tissue distribution of mRNAs for two proteins that are related to the band 3 Cl-/HCO3-exchanger.

O17966	TOP1_CAEEL	DNA topoisomerase 1	8647074	cDNA cloning, expression, and chromosomal localization of Caenorhabditis elegans DNA topoisomerase I.

P36874	PP1GA_XENLA	Serine/threonine-protein phosphatase PP1-gamma catalytic subunit A	17448463	Nuclear envelope precursor vesicle targeting to chromatin is stimulated by protein phosphatase 1 in Xenopus egg extracts.

Q13490	BIRC2_HUMAN	Baculoviral IAP repeat-containing protein 2	19153467	The structure of the BIR3 domain of cIAP1 in complex with the N- terminal peptides of SMAC and caspase-9.

Q92956	TNR14_HUMAN	Tumor necrosis factor receptor superfamily member 14	9153189	ATAR, a novel tumor necrosis factor receptor family member, signals through TRAF2 and TRAF5.

P67870	CSK2B_HUMAN	Casein kinase II subunit beta	2513884	Cloning and characterization of a cDNA encoding the beta subunit of human casein kinase II.

P29747	CREBA_DROME	Cyclic AMP response element-binding protein A	1532159	A Drosophila CREB/ATF transcriptional activator binds to both fat body- and liver-specific regulatory elements.

P94063	HAL3B_ARATH	Probable phosphopantothenoylcysteine decarboxylase	10652125	Arabidopsis thaliana AtHAL3: a flavoprotein related to salt and osmotic tolerance and plant growth.

Q14142	TRI14_HUMAN	Tripartite motif-containing protein 14	11331580	The tripartite motif family identifies cell compartments.

Q61458	CCNH_MOUSE	Cyclin-H	11319144	Meiotic expression of the cyclin H/Cdk7 complex in male germ cells of the mouse.

Q8IBP1	YPF16_PLAF7	Uncharacterized protein PF07_0086	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

P01716	LV402_HUMAN	Ig lambda chain V-IV region X	4883841	Immunoglobulin lambda-chains. The complete amino acid sequence of a Bence-Jones protein.

P08461	ODP2_RAT	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial	1581353	Molecular cloning of dihydrolipoamide acetyltransferase of the rat pyruvate dehydrogenase complex: sequence comparison and evolutionary relationship to other dihydrolipoamide acyltransferases.

Q9UKI8	TLK1_HUMAN	Serine/threonine-protein kinase tousled-like 1	9427565	cDNA cloning and chromosomal mapping of genes encoding novel protein kinases termed PKU-alpha and PKU-beta, which have nuclear localization signal.

Q91550	ILF3A_XENLA	Interleukin enhancer-binding factor 3-A	8631310	Overexpression of poly(A) binding protein prevents maturation- specific deadenylation and translational inactivation in Xenopus oocytes.

Q9SYN1	PEN6_ARATH	Pentacyclic triterpene synthase 6	17263431	Origin of structural diversity in natural triterpenes: direct synthesis of seco-triterpene skeletons by oxidosqualene cyclase.

Q14BI7	TDRD9_MOUSE	Putative ATP-dependent RNA helicase TDRD9	20059948	The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline.

P39923	NPR2_YEAST	Nitrogen permease regulator 2	12869630	Anticancer drug resistance induced by disruption of the Saccharomyces cerevisiae NPR2 gene: a novel component involved in cisplatin- and doxorubicin-provoked cell kill.

Q9FNI7	CSLA2_ARATH	Glucomannan 4-beta-mannosyltransferase 2	15647349	Expression of cellulose synthase-like (Csl) genes in insect cells reveals that CslA family members encode mannan synthases.

C0LGQ4	MRH1_ARATH	Probable LRR receptor-like serine/threonine-protein kinase MRH1	16367956	Analysis of the root-hair morphogenesis transcriptome reveals the molecular identity of six genes with roles in root-hair development in Arabidopsis.

Q6VRB0	ANM1B_XENLA	Protein arginine N-methyltransferase 1-B	18636753	Methylation of Xilf3 by Xprmt1b alters its DNA, but not RNA, binding activity.

Q8WMU5	FZD6_CANFA	Frizzled-6	15265686	Wnt-4 activates the canonical beta-catenin-mediated Wnt pathway and binds Frizzled-6 CRD: functional implications of Wnt/beta-catenin activity in kidney epithelial cells.

Q9GUM2	BRE4_CAEEL	Beta-1,4-N-acetylgalactosaminyltransferase bre-4	12944392	Resistance to a bacterial toxin is mediated by removal of a conserved glycosylation pathway required for toxin-host interactions.

P62304	RUXE_HUMAN	Small nuclear ribonucleoprotein E	11574479	Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein.

Q9Y623	MYH4_HUMAN	Myosin-4	10388558	Comparative sequence analysis of the complete human sarcomeric myosin heavy chain family: implications for functional diversity.

B2RU80	PTPRB_MOUSE	Receptor-type tyrosine-protein phosphatase beta	16514057	Vascular endothelial cell-specific phosphotyrosine phosphatase (VE- PTP) activity is required for blood vessel development.

Q12297	TAF3_YEAST	Transcription initiation factor TFIID subunit 3	12138208	Molecular characterization of Saccharomyces cerevisiae TFIID.

Q9UIS9	MBD1_HUMAN	Methyl-CpG-binding domain protein 1	9774669	Identification and characterization of a family of mammalian methyl- CpG binding proteins.

P32452	PHA2_YEAST	Putative prephenate dehydratase	7502583	Sequencing analysis of a 24.7 kb fragment of yeast chromosome XIV identifies six known genes, a new member of the hexose transporter family and ten new open reading frames.

P84797	AFAGR_AGRCY	Agrocybin	15629530	Agrocybin, an antifungal peptide from the edible mushroom Agrocybe cylindracea.

P49918	CDN1C_HUMAN	Cyclin-dependent kinase inhibitor 1C	7729684	p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene.

P53851	TEX1_YEAST	Protein TEX1	11979277	TREX is a conserved complex coupling transcription with messenger RNA export.

Q94128	WRT1_CAEEL	Warthog protein 1	8689684	Hedgehog patterning activity: role of a lipophilic modification mediated by the carboxy-terminal autoprocessing domain.

Q9NNX9	VCX3_HUMAN	Variable charge X-linked protein 3	10903929	A member of a gene family on Xp22.3, VCX-A, is deleted in patients with X-linked nonspecific mental retardation.

Q67Y93	KRP1_ARATH	Cyclin-dependent kinase inhibitor 1	18005227	Degradation of the cyclin-dependent kinase inhibitor KRP1 is regulated by two different ubiquitin E3 ligases.

Q14524	SCN5A_HUMAN	Sodium channel protein type 5 subunit alpha	7889574	SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome.

P0ACG8	HSLR_ECOLI	Heat shock protein 15	10675343	Hsp15: a ribosome-associated heat shock protein.

Q3E841	YN034_YEAST	Uncharacterized protein YNR034W-A	14562095	Global analysis of protein localization in budding yeast.

Q13705	AVR2B_HUMAN	Activin receptor type-2B	9916847	Left-right axis malformations associated with mutations in ACVR2B, the gene for human activin receptor type IIB.

P38344	REI1_YEAST	Pre-60S factor REI1	16651379	A functional network involved in the recycling of nucleocytoplasmic pre-60S factors.

P40855	PEX19_HUMAN	Peroxisomal biogenesis factor 19	10704444	PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis.

P42669	PURA_MOUSE	Transcriptional activator protein Pur-alpha	10318844	Molecular interactions between single-stranded DNA-binding proteins associated with an essential MCAT element in the mouse smooth muscle alpha-actin promoter.

Q12044	RCN2_YEAST	Regulator of calcineurin 2	14562095	Global analysis of protein localization in budding yeast.

P15891	ABP1_YEAST	Actin-binding protein	11950888	Sla1p couples the yeast endocytic machinery to proteins regulating actin dynamics.

Q03010	UME1_YEAST	Transcriptional regulatory protein UME1	16286008	Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex.

P52803	EFNA5_HUMAN	Ephrin-A5	9245480	LERK-7: a ligand of the Eph-related kinases is developmentally regulated in the brain.

P53220	TIM21_YEAST	Mitochondrial import inner membrane translocase subunit TIM21	15878866	Role of Tim21 in mitochondrial translocation contact sites.

Q54I98	SMT1_DICDI	Probable cycloartenol-C-24-methyltransferase 1	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P35555	FBN1_HUMAN	Fibrillin-1	7691719	Fibrillin binds calcium and is coded by cDNAs that reveal a multidomain structure and alternatively spliced exons at the 5' end.

Q12042	YP162_YEAST	Vacuolar membrane protein YPL162C	14562095	Global analysis of protein localization in budding yeast.

Q6T264	MAML1_MOUSE	Mastermind-like protein 1	15019995	Cloning and functional characterization of the murine mastermind-like 1 (Maml1) gene.

Q9BQ50	TREX2_HUMAN	Three prime repair exonuclease 2	10391904	Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3'-->5' exonucleases.

Q9FN69	GL3_ARATH	Transcription factor GLABRA 3	15361138	Comprehensive identification of Arabidopsis thaliana MYB transcription factors interacting with R/B-like BHLH proteins.

Q3MI48	JSPR1_MOUSE	Junctional sarcoplasmic reticulum protein 1	12871958	The novel skeletal muscle sarcoplasmic reticulum JP-45 protein. Molecular cloning, tissue distribution, developmental expression, and interaction with alpha 1.1 subunit of the voltage-gated calcium channel.

P20742	PZP_HUMAN	Pregnancy zone protein	2692707	Pregnancy zone protein, a proteinase-binding macroglobulin. Interactions with proteinases and methylamine.

O30434	ETCP_ENTFC	Bacteriocin enterocin-P	9361419	Biochemical and genetic characterization of enterocin P, a novel sec- dependent bacteriocin from Enterococcus faecium P13 with a broad antimicrobial spectrum.

O94259	UTP16_SCHPO	Probable U3 small nucleolar RNA-associated protein 16	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P49631	RL43_YEAST	60S ribosomal protein L43	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q12123	DCS2_YEAST	Protein DCS2	14562095	Global analysis of protein localization in budding yeast.

P83888	TBG1_RAT	Tubulin gamma-1 chain	10470852	Structure of rat gamma-tubulin and its binding to HP33.

P32525	ECM25_YEAST	Protein ECM25	14562095	Global analysis of protein localization in budding yeast.

Q9URY2	ALP7_SCHPO	Microtubule protein alp7	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q16512	PKN1_HUMAN	Serine/threonine-protein kinase N1	8135837	A novel protein kinase with leucine zipper-like sequences: its catalytic domain is highly homologous to that of protein kinase C.

P56537	IF6_HUMAN	Eukaryotic translation initiation factor 6	9374518	Isolation of a novel beta4 integrin-binding protein (p27(BBP)) highly expressed in epithelial cells.

P38911	FKBP3_YEAST	FK506-binding nuclear protein	7925954	Purification of FKBP-70, a novel immunophilin from Saccharomyces cerevisiae, and cloning of its structural gene, FPR3.

Q8W585	FTSH8_ARATH	ATP-dependent zinc metalloprotease FTSH 8, chloroplastic	14630971	Coordinated regulation and complex formation of yellow variegated1 and yellow variegated2, chloroplastic FtsH metalloproteases involved in the repair cycle of photosystem II in Arabidopsis thylakoid membranes.

O33244	PSA_MYCTU	Proteasome subunit alpha	16468985	Mycobacterium tuberculosis prcBA genes encode a gated proteasome with broad oligopeptide specificity.

P22465	ANX10_DROME	Annexin-B10	2141610	Two novel annexins from Drosophila melanogaster. Cloning, characterization, and differential expression in development.

A5PKW4	PSD1_HUMAN	PH and SEC7 domain-containing protein 1	9417912	Identification of a novel gene, PSD, adjacent to NFKB2/lyt-10, which contains Sec7 and pleckstrin-homology domains.

P01744	HV104_HUMAN	Ig heavy chain V-I region ND	6815656	Cloning and sequence determination of the gene for the human immunoglobulin epsilon chain expressed in a myeloma cell line.

P16143	PO2F1_XENLA	POU domain, class 2, transcription factor 1	1990276	A variant octamer motif in a Xenopus H2B histone gene promoter is not required for transcription in frog oocytes.

Q17381	PHA4_CAEEL	Defective pharyngeal development protein 4	9584117	pha-4 is Ce-fkh-1, a fork head/HNF-3alpha,beta,gamma homolog that functions in organogenesis of the C. elegans pharynx.

P48067	SC6A9_HUMAN	Sodium- and chloride-dependent glycine transporter 1	8183239	Cloning of the human glycine transporter type 1: molecular and pharmacological characterization of novel isoform variants and chromosomal localization of the gene in the human and mouse genomes.

Q8WZ42	TITIN_HUMAN	Titin	7569978	Titins, giant proteins in charge of muscle ultrastructure and elasticity.

P39515	TIM17_YEAST	Mitochondrial import inner membrane translocase subunit TIM17	7919535	SMS1, a high-copy suppressor of the yeast mas6 mutant, encodes an essential inner membrane protein required for mitochondrial protein import.

Q17374	SUP10_CAEEL	Putative potassium channel regulatory protein sup-10	14534247	sup-9, sup-10, and unc-93 may encode components of a two-pore K+ channel that coordinates muscle contraction in Caenorhabditis elegans.

O43194	GPR39_HUMAN	G-protein coupled receptor 39	9441746	Cloning and characterization of two human G protein-coupled receptor genes (GPR38 and GPR39) related to the growth hormone secretagogue and neurotensin receptors.

Q9Z2C8	YBOX2_MOUSE	Y-box-binding protein 2	10772793	A sequence-specific RNA binding complex expressed in murine germ cells contains MSY2 and MSY4.

P25932	ESCA_DROME	Protein escargot	7958894	Diploidy of Drosophila imaginal cells is maintained by a transcriptional repressor encoded by escargot.

P49018	GPI8_YEAST	GPI-anchor transamidase	8978684	Yeast Gpi8p is essential for GPI anchor attachment onto proteins.

Q99PJ2	TRIM8_MOUSE	Probable E3 ubiquitin-protein ligase TRIM8	11331580	The tripartite motif family identifies cell compartments.

Q9UAS6	FTSJ1_DROME	FtsJ methyltransferase domain-containing protein 1 homolog	10068643	adrift, a novel bnl-induced Drosophila gene, required for tracheal pathfinding into the CNS.

Q6NS46	RRP5_MOUSE	Protein RRP5 homolog	10229231	Regulation of Fas ligand expression and cell death by apoptosis- linked gene 4.

P25929	NPY1R_HUMAN	Neuropeptide Y receptor type 1	1321422	Cloned human neuropeptide Y receptor couples to two different second messenger systems.

Q9XZU1	XPO2_DROME	Exportin-2	11944946	Dcas is required for importin-alpha3 nuclear export and mechano- sensory organ cell fate specification in Drosophila.

Q14954	KI2S1_HUMAN	Killer cell immunoglobulin-like receptor 2DS1	8627176	The human leukocyte antigen (HLA)-C-specific 'activatory' or 'inhibitory' natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions.

Q8STE5	CED12_CAEEL	Cell death abnormality protein 12	15247908	PH domain of ELMO functions in trans to regulate Rac activation via Dock180.

Q7TNK1	RFX4_MOUSE	Transcription factor RFX4	12925582	Graded phenotypic response to partial and complete deficiency of a brain-specific transcript variant of the winged helix transcription factor RFX4.

P35194	UTP20_YEAST	U3 small nucleolar RNA-associated protein 20	14562095	Global analysis of protein localization in budding yeast.

O95948	ONEC2_HUMAN	One cut domain family member 2	9915796	OC-2, a novel mammalian member of the ONECUT class of homeodomain transcription factors whose function in liver partially overlaps with that of hepatocyte nuclear factor-6.

Q567J8	OSR2_DANRE	Protein odd-skipped-related 2	17011543	Odd-skipped genes encode repressors that control kidney development.

P20009	DLL_DROME	Homeotic protein distal-less	2564639	Distal-less encodes a homoeodomain protein required for limb development in Drosophila.

O60921	HUS1_HUMAN	Checkpoint protein HUS1	10846170	HDAC1, a histone deacetylase, forms a complex with Hus1 and Rad9, two G2/M checkpoint Rad proteins.

P21554	CNR1_HUMAN	Cannabinoid receptor 1	1718258	Molecular cloning of a human cannabinoid receptor which is also expressed in testis.

Q03238	GRAM_RAT	Granzyme M	1447189	Purification and cloning of a novel serine protease, RNK-Met-1, from the granules of a rat natural killer cell leukemia.

Q13569	TDG_HUMAN	G/T mismatch-specific thymine DNA glycosylase	8662714	Cloning and expression of human G/T mismatch-specific thymine-DNA glycosylase.

Q9FKB6	Y5880_ARATH	BTB/POZ domain-containing protein At5g48800	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q9NHC3	CED2_CAEEL	Cell death abnormality protein 2	11703940	C. elegans CED-12 acts in the conserved crkII/DOCK180/Rac pathway to control cell migration and cell corpse engulfment.

O43002	SC61B_SCHPO	Protein transport protein sec61 subunit beta	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O08984	LBR_RAT	Lamin-B receptor	12438562	Mapping sites of O-GlcNAc modification using affinity tags for serine and threonine post-translational modifications.

Q26622	SHR2_STRPU	Orphan steroid hormone receptor 2	9664037	Embryonic and post-embryonic utilization and subcellular localization of the nuclear receptor SpSHR2 in the sea urchin.

P86101	SCBM1_PERVE	Sulfocarbamoylase-1	18599388	Purification and characterization of paralytic shellfish toxin- transforming enzyme, sulfocarbamoylase I, from the Japanese bivalve Peronidia venulosa.

Q9EQ60	CAC1H_RAT	Voltage-dependent T-type calcium channel subunit alpha-1H	11073957	Molecular and functional characterization of a family of rat brain T- type calcium channels.

P56374	CRBA4_RAT	Beta-crystallin A4	11773034	Lens proteomics: analysis of rat crystallin sequences and two- dimensional electrophoresis map.

Q12851	M4K2_HUMAN	Mitogen-activated protein kinase kinase kinase kinase 2	11784851	Direct activation of mitogen-activated protein kinase kinase kinase MEKK1 by the Ste20p homologue GCK and the adapter protein TRAF2.

Q9LIE5	FHY3_ARATH	Protein FAR-RED ELONGATED HYPOCOTYL 3	11889039	Arabidopsis FHY3 defines a key phytochrome A signaling component directly interacting with its homologous partner FAR1.

Q99N28	CADM3_MOUSE	Cell adhesion molecule 3	15893517	Nectin-like molecule 1 is a protein 4.1N associated protein and recruits protein 4.1N from cytoplasm to the plasma membrane.

Q96EB6	SIRT1_HUMAN	NAD-dependent deacetylase sirtuin-1	18235501	DBC1 is a negative regulator of SIRT1.

P33750	DCA13_YEAST	Protein SOF1	8508778	A U3 snoRNP protein with homology to splicing factor PRP4 and G beta domains is required for ribosomal RNA processing.

P49458	SRP09_HUMAN	Signal recognition particle 9 kDa protein	7730321	Human signal recognition particle (SRP) Alu-associated protein also binds Alu interspersed repeat sequence RNAs. Characterization of human SRP9.

Q86XK2	FBX11_HUMAN	F-box only protein 11	10531035	Identification of a family of human F-box proteins.

P01298	PAHO_HUMAN	Pancreatic prohormone	6373251	A cDNA encoding a small common precursor for human pancreatic polypeptide and pancreatic icosapeptide.

P11986	INO1_YEAST	Inositol-3-phosphate synthase	8813765	Sequence analysis of a 40.7 kb segment from the left arm of yeast chromosome X reveals 14 known genes and 13 new open reading frames including homologues of genes clustered on the right arm of chromosome XI.

Q9H492	MLP3A_HUMAN	Microtubule-associated proteins 1A/1B light chain 3A	12740394	Post-translational modifications of three members of the human MAP1LC3 family and detection of a novel type of modification for MAP1LC3B.

Q9XWD6	CED1_CAEEL	Cell death abnormality protein 1	11729193	Interaction of CED-6/GULP, an adapter protein involved in engulfment of apoptotic cells with CED-1 and CD91/low density lipoprotein receptor-related protein (LRP).

Q99207	NOP14_YEAST	Nucleolar complex protein 14	11694595	Novel stress-responsive genes EMG1 and NOP14 encode conserved, interacting proteins required for 40S ribosome biogenesis.

P13599	FCGRN_RAT	IgG receptor FcRn large subunit p51	2911353	An Fc receptor structurally related to MHC class I antigens.

Q05541	NSE3_YEAST	Non-structural maintenance of chromosome element 3	14562095	Global analysis of protein localization in budding yeast.

Q13621	S12A1_HUMAN	Solute carrier family 12 member 1	8640224	Bartter's syndrome, hypokalemic alkalosis with hypercalciuria, is caused by mutations in the Na-K-2Cl cotransporter NKCC2.

Q9WUU8	TNIP1_MOUSE	TNFAIP3-interacting protein 1	10385526	The zinc finger protein A20 inhibits TNF-induced NF-B-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-B-inhibiting protein ABIN.

O00461	GOLI4_HUMAN	Golgi integral membrane protein 4	9201717	Sequence and overexpression of GPP130/GIMPc: evidence for saturable pH-sensitive targeting of a type II early Golgi membrane protein.

O60091	RM24_SCHPO	60S ribosomal protein L24, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q6KFX9	RFNG_DANRE	Beta-1,3-N-acetylglucosaminyltransferase radical fringe	15068793	Notch activation regulates the segregation and differentiation of rhombomere boundary cells in the zebrafish hindbrain.

Q93Z08	E136_ARATH	Glucan endo-1,3-beta-glucosidase 6	12805588	Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis.

P30510	1C14_HUMAN	HLA class I histocompatibility antigen, Cw-14 alpha chain	2787363	The structure and expression of genes encoding serologically undetected HLA-C locus antigens.

P42760	GSTF1_ARATH	Glutathione S-transferase 1	8253194	Characterization of two cDNAs (ERD11 and ERD13) for dehydration- inducible genes that encode putative glutathione S-transferases in Arabidopsis thaliana L.

Q24306	IAP1_DROME	Apoptosis 1 inhibitor	18259196	The interaction of DIAP1 with dOmi/HtrA2 regulates cell death in Drosophila.

O75494	SRS10_HUMAN	Serine/arginine-rich splicing factor 10	9774382	Oncoprotein TLS interacts with serine-arginine proteins involved in RNA splicing.

O84944	SSEA_SALTY	Type III secretion system chaperone sseA	15256549	The SPI2-encoded SseA chaperone has discrete domains required for SseB stabilization and export, and binds within the C-terminus of SseB and SseD.

P50895	BCAM_HUMAN	Basal cell adhesion molecule	7954395	Molecular cloning of the B-CAM cell surface glycoprotein of epithelial cancers: a novel member of the immunoglobulin superfamily.

P55854	SUMO3_HUMAN	Small ubiquitin-related modifier 3	18538659	Mechanism and consequences for paralog-specific sumoylation of ubiquitin-specific protease 25.

Q03981	CSN9_YEAST	COP9 signalosome complex subunit 9	12672462	The COP9 signalosome-like complex in S. cerevisiae and links to other PCI complexes.

Q9H341	O51M1_HUMAN	Olfactory receptor 51M1	11121057	Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.

Q9VTE2	SUUR_DROME	Protein suppressor of underreplication	12644953	Influence of the SuUR gene on intercalary heterochromatin in Drosophila melanogaster polytene chromosomes.

Q3UHN9	NDST1_MOUSE	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1	10664446	Targeted disruption of NDST-1 gene leads to pulmonary hypoplasia and neonatal respiratory distress in mice.

Q9FJA2	TT2_ARATH	Transcription factor TT2	15361138	Comprehensive identification of Arabidopsis thaliana MYB transcription factors interacting with R/B-like BHLH proteins.

P35525	CLCN2_RAT	Chloride channel protein 2	1311421	A chloride channel widely expressed in epithelial and non-epithelial cells.

O43676	NDUB3_HUMAN	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3	9425316	Identification and primary structure of five human NADH-ubiquinone oxidoreductase subunits.

Q61658	HESX1_MOUSE	Homeobox expressed in ES cells 1	9620767	Mutations in the homeobox gene HESX1/Hesx1 associated with septo- optic dysplasia in human and mouse.

Q9M0B6	GAE1_ARATH	UDP-glucuronate 4-epimerase 1	15247385	The biosynthesis of D-galacturonate in plants. Functional cloning and characterization of a membrane-anchored UDP-D-glucuronate 4-epimerase from Arabidopsis.

P33767	OSTB_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1	15831493	Subunits of the translocon interact with components of the oligosaccharyl transferase complex.

Q99963	SH3G3_HUMAN	Endophilin-A3	9169142	A novel SH3-containing human gene family preferentially expressed in the central nervous system.

Q9W0T1	NU301_DROME	Nucleosome-remodeling factor subunit NURF301	11583616	Dual functions of largest NURF subunit NURF301 in nucleosome sliding and transcription factor interactions.

O94651	PEP12_SCHPO	Syntaxin pep12	14575697	Identification of a SNARE protein required for vacuolar protein transport in Schizosaccharomyces pombe.

O43598	RCL_HUMAN	Deoxyribonucleoside 5'-monophosphate N-glycosidase	9271375	Identification of putative c-Myc-responsive genes: characterization of rcl, a novel growth-related gene.

Q9HBV1	POPD3_HUMAN	Popeye domain-containing protein 3	10882522	Isolation and characterization of the novel popeye gene family expressed in skeletal muscle and heart.

P77757	ARNC_ECOLI	Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase	15695810	A formyltransferase required for polymyxin resistance in Escherichia coli and the modification of lipid A with 4-amino-4-deoxy-L-arabinose: identification and function of UDP-4-deoxy-4-formamido-L-arabinose.

Q9DA37	SAMD8_MOUSE	Sphingomyelin synthase-related protein 1	14685263	Identification of a family of animal sphingomyelin synthases.

P56745	CLD1_RAT	Claudin-1	11159859	Claudin-1 is not restricted to tight junctions in the rat epididymis.

O43255	SIAH2_HUMAN	E3 ubiquitin-protein ligase SIAH2	9334332	Mammalian homologs of seven in absentia regulate DCC via the ubiquitin-proteasome pathway.

P00806	NAAA_BPT7	N-acetylmuramoyl-L-alanine amidase	9670025	Structure of T7 RNA polymerase complexed to the transcriptional inhibitor T7 lysozyme.

Q62696	DLG1_RAT	Disks large homolog 1	12933808	CaMKII-dependent phosphorylation regulates SAP97/NR2A interaction.

Q9EQU3	TLR9_MOUSE	Toll-like receptor 9	14993594	Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection.

Q14011	CIRBP_HUMAN	Cold-inducible RNA-binding protein	16513844	Post-transcriptional regulation of thioredoxin by the stress inducible heterogenous ribonucleoprotein A18.

Q9SU00	CML2_ARATH	Calmodulin-like protein 2	15634699	Genetic and molecular identification of genes required for female gametophyte development and function in Arabidopsis.

P00488	F13A_HUMAN	Coagulation factor XIII A chain	2877456	Primary structure of blood coagulation factor XIIIa (fibrinoligase, transglutaminase) from human placenta.

Q38913	EXTN1_ARATH	Extensin-1	10333585	The Arabidopsis extensin gene is developmentally regulated, is induced by wounding, methyl jasmonate, abscisic and salicylic acid, and codes for a protein with unusual motifs.

P31350	RIR2_HUMAN	Ribonucleoside-diphosphate reductase subunit M2	1627826	Sequence analysis of the large and small subunits of human ribonucleotide reductase.

Q9XIE3	HS17A_ARATH	17.6 kDa class I heat shock protein 1	11576425	At-HSP17.6A, encoding a small heat-shock protein in Arabidopsis, can enhance osmotolerance upon overexpression.

Q12032	AIM41_YEAST	Altered inheritance of mitochondria protein 41, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

Q62711	PLCD4_RAT	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-4	8550568	Molecular cloning, splice variants, expression, and purification of phospholipase C-delta 4.

P01760	HV105_HUMAN	Ig heavy chain V-I region WOL	7028111	Amino acid sequence of the variable regions of heavy chains from two idiotypically cross-reactive human IgM anti-gamma-globulins of the Wa group.

O43570	CAH12_HUMAN	Carbonic anhydrase 12	9636197	Human carbonic anhydrase XII: cDNA cloning, expression, and chromosomal localization of a carbonic anhydrase gene that is overexpressed in some renal cell cancers.

O13995	DAP1_SCHPO	Cytochrome P450 regulator dap1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q15125	EBP_HUMAN	3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	7706302	Phenylalkylamine Ca2+ antagonist binding protein. Molecular cloning, tissue distribution, and heterologous expression.

Q8ILR9	LRR1_PLAF7	LRR domain-containing protein PF14_0175	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

O14035	YEME_SCHPO	Uncharacterized permease C29B12.14c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P25694	CDC48_YEAST	Cell division control protein 48	11740563	The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol.

P63072	UBD_MOUSE	Ubiquitin D	11445583	The ubiquitin-like protein FAT10 forms covalent conjugates and induces apoptosis.

Q28ET4	VENT1_XENTR	Homeobox protein vent1	12050139	A study of mesoderm patterning through the analysis of the regulation of Xmyf-5 expression.

P13989	TNSB_ECOLX	Transposon Tn7 transposition protein tnsB	10704304	A minimal system for Tn7 transposition: the transposon-encoded proteins TnsA and TnsB can execute DNA breakage and joining reactions that generate circularized Tn7 species.

P40955	CHS6_YEAST	Chitin biosynthesis protein CHS6	9614194	Chs6p-dependent anterograde transport of Chs3p from the chitosome to the plasma membrane in Saccharomyces cerevisiae.

Q59E55	NAB_DROME	NGFI-A-binding protein homolog	12508226	Drosophila NAB (dNAB) is an orphan transcriptional co-repressor required for correct CNS and eye development.

Q09892	HOG1_SCHPO	Mitogen-activated protein kinase sty1	12589433	Mkp1 and Mkp2, two MAPKAP-kinase homologues in Schizosaccharomyces pombe, interact with the MAP kinase Sty1.

Q9UJW2	TINAG_HUMAN	Tubulointerstitial nephritis antigen	1762287	Distribution of tubulointerstitial nephritis antigen and evidence for multiple forms.

P34897	GLYM_HUMAN	Serine hydroxymethyltransferase, mitochondrial	8505317	Cloning of human cDNAs encoding mitochondrial and cytosolic serine hydroxymethyltransferases and chromosomal localization.

P40394	ADH7_HUMAN	Alcohol dehydrogenase class 4 mu/sigma chain	7876099	Expression and kinetic characterization of recombinant human stomach alcohol dehydrogenase. Active-site amino acid sequence explains substrate specificity compared with liver isozymes.

Q24292	DS_DROME	Protein dachsous	7601355	Dachsous encodes a member of the cadherin superfamily that controls imaginal disc morphogenesis in Drosophila.

O54724	PTRF_MOUSE	Polymerase I and transcript release factor	9582279	Cloning and functional characterization of PTRF, a novel protein which induces dissociation of paused ternary transcription complexes.

Q96F07	CYFP2_HUMAN	Cytoplasmic FMR1-interacting protein 2	15048733	CYFIP2 is highly abundant in CD4+ cells from multiple sclerosis patients and is involved in T cell adhesion.

P31801	CHAA_ECOLI	Calcium/proton antiporter	8496184	Cloning and characterization of a putative Ca2+/H+ antiporter gene from Escherichia coli upon functional complementation of Na+/H+ antiporter-deficient strains by the overexpressed gene.

P40160	RIO2_YEAST	Serine/threonine-protein kinase RIO2	15167894	The ribosomal protein Rps15p is required for nuclear exit of the 40S subunit precursors in yeast.

Q69ZX8	ABLM3_MOUSE	Actin-binding LIM protein 3	17194709	Two novel members of the ABLIM protein family, ABLIM-2 and -3, associate with STARS and directly bind F-actin.

Q9NPB9	CCRL1_HUMAN	C-C chemokine receptor type 11	10706668	Identification of a novel chemokine receptor that binds dendritic cell- and T cell-active chemokines including ELC, SLC, and TECK.

Q07954	LRP1_HUMAN	Prolow-density lipoprotein receptor-related protein 1	3266596	Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor.

P33767	OSTB_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1	1724755	An essential 45 kDa yeast transmembrane protein reacts with anti- nuclear pore antibodies: purification of the protein, immunolocalization and cloning of the gene.

Q8R4V1	NFAM1_MOUSE	NFAT activation molecule 1	15143214	NFAM1, an immunoreceptor tyrosine-based activation motif-bearing molecule that regulates B cell development and signaling.

P23819	GRIA2_MOUSE	Glutamate receptor 2	10340301	The protein kinase C alpha binding protein PICK1 interacts with short but not long form alternative splice variants of AMPA receptor subunits.

Q7G192	ALDO2_ARATH	Aldehyde oxidase 2	10739959	Functional expression of two Arabidopsis aldehyde oxidases in the yeast Pichia pastoris.

P17883	SKI3_YEAST	Superkiller protein 3	10744028	The yeast antiviral proteins Ski2p, Ski3p, and Ski8p exist as a complex in vivo.

Q5U4X3	MEI3A_XENLA	Homeobox protein meis3-A	10096059	A Meis family protein caudalizes neural cell fates in Xenopus.

Q9SPL3	AMP23_MACIN	Vicilin-like antimicrobial peptides 2-3	10571855	A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels.

Q923T7	TRIM7_MOUSE	Tripartite motif-containing protein 7	11331580	The tripartite motif family identifies cell compartments.

Q9Z2P3	TNFL4_RAT	Tumor necrosis factor ligand superfamily member 4	9790919	Identification of rat OX40 ligand by molecular cloning.

Q05518	PAL1_YEAST	Uncharacterized protein YDR348C	14562095	Global analysis of protein localization in budding yeast.

Q9HC97	GPR35_HUMAN	G-protein coupled receptor 35	16754668	Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35.

Q8N4C6	NIN_HUMAN	Ninein	12927815	Molecular characterization of human ninein protein: two distinct subdomains required for centrosomal targeting and regulating signals in cell cycle.

P49769	PSN1_MOUSE	Presenilin-1	10854253	Isolation and characterization of novel presenilin binding protein.

P60484	PTEN_HUMAN	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	15951562	Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases.

P23226	MA205_DROME	205 kDa microtubule-associated protein	1703540	Analysis of the primary sequence and microtubule-binding region of the Drosophila 205K MAP.

P06703	S10A6_HUMAN	Protein S100-A6	11937060	Crystal structures of S100A6 in the Ca(2+)-free and Ca(2+)-bound states: the calcium sensor mechanism of S100 proteins revealed at atomic resolution.

Q8VYR5	PP351_ARATH	Pentatricopeptide repeat-containing protein At4g35850, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q5SF94	AAAP_ANAML	Appendage-associated protein	15557651	Identification of a novel Anaplasma marginale appendage-associated protein that localizes with actin filaments during intraerythrocytic infection.

P36138	YK25_YEAST	Uncharacterized protein YKR045C	11914276	Subcellular localization of the yeast proteome.

Q80YV3	TRRAP_MOUSE	Transformation/transcription domain-associated protein	11544477	Disruption of Trrap causes early embryonic lethality and defects in cell cycle progression.

Q99650	OSMR_HUMAN	Oncostatin-M-specific receptor subunit beta	8999038	Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation.

O94163	XYNF1_ASPOR	Endo-1,4-beta-xylanase F1	10586505	Purification and characterization of the overexpressed Aspergillus oryzae xylanase, XynF1.

Q86UE8	TLK2_HUMAN	Serine/threonine-protein kinase tousled-like 2	10523312	Mammalian homologues of the plant tousled gene code for cell-cycle- regulated kinases with maximal activities linked to ongoing DNA replication.

P40383	XRN1_SCHPO	5'-3' exoribonuclease 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P84078	ARF1_MOUSE	ADP-ribosylation factor 1	8947846	Structure and intracellular localization of mouse ADP-ribosylation factors type 1 to type 6 (ARF1-ARF6).

Q9SW95	SYNC2_ARATH	Asparaginyl-tRNA synthetase, cytoplasmic 2	10824085	Duplication and quadruplication of Arabidopsis thaliana cysteinyl- and asparaginyl-tRNA synthetase genes of organellar origin.

Q06108	YP115_YEAST	Uncharacterized PH domain-containing protein YPR115W	14562095	Global analysis of protein localization in budding yeast.

Q61060	FOXD3_MOUSE	Forkhead box protein D3	8798505	Genesis, a winged helix transcriptional repressor with expression restricted to embryonic stem cells.

Q9UT46	MOC3_SCHPO	Transcriptional regulatory protein moc3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P58681	TLR7_MOUSE	Toll-like receptor 7	18305481	UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes.

P32189	GLPK_HUMAN	Glycerol kinase	8401584	Genomic scanning for expressed sequences in Xp21 identifies the glycerol kinase gene.

O75019	LIRA1_HUMAN	Leukocyte immunoglobulin-like receptor subfamily A member 1	9548455	A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules.

P53838	BOR1_YEAST	Boron transporter 1	16565073	Enolase activates homotypic vacuole fusion and protein transport to the vacuole in yeast.

Q966L9	GLH2_CAEEL	ATP-dependent RNA helicase glh-2	8943022	Multiple potential germ-line helicases are components of the germ- line-specific P granules of Caenorhabditis elegans.

Q9R1C0	TAF7_MOUSE	Transcription initiation factor TFIID subunit 7	10438527	Isolation of mouse TFIID and functional characterization of TBP and TFIID in mediating estrogen receptor and chromatin transcription.

P18115	THAB_XENLA	Thyroid hormone receptor alpha-B	2402492	Xenopus laevis alpha and beta thyroid hormone receptors.

Q8R4U7	LUZP1_MOUSE	Leucine zipper protein 1	8812416	Identification, molecular characterization, and chromosomal localization of the cDNA encoding a novel leucine zipper motif- containing protein.

Q92331	VPS5_YEAST	Vacuolar protein sorting-associated protein 5	9175702	The yeast VPS5/GRD2 gene encodes a sorting nexin-1-like protein required for localizing membrane proteins to the late Golgi.

Q23316	NICA_CAEEL	Nicastrin	10804188	aph-2 encodes a novel extracellular protein required for GLP-1- mediated signaling.

O70521	RGS19_RAT	Regulator of G-protein signaling 19	9571244	RGS-GAIP, a GTPase-activating protein for Galphai heterotrimeric G proteins, is located on clathrin-coated vesicles.

P78325	ADAM8_HUMAN	Disintegrin and metalloproteinase domain-containing protein 8	9126482	CD156 (human ADAM8): expression, primary amino acid sequence, and gene location.

O75818	RPP40_HUMAN	Ribonuclease P protein subunit p40	9630247	Autoantigenic properties of some protein subunits of catalytically active complexes of human ribonuclease P.

P09327	VILI_HUMAN	Villin-1	2846586	Sequence of human villin: a large duplicated domain homologous with other actin-severing proteins and a unique small carboxy-terminal domain related to villin specificity.

P17516	AK1C4_HUMAN	Aldo-keto reductase family 1 member C4	7650035	Substrate specificity, gene structure, and tissue-specific distribution of multiple human 3 alpha-hydroxysteroid dehydrogenases.

P0AB65	ACYP_ECOLI	Acylphosphatase	17134700	The intrachain disulfide bridge is responsible of the unusual stability properties of novel acylphosphatase from Escherichia coli.

P32781	AGA2_YEAST	A-agglutinin-binding subunit	11292808	Interaction of alpha-agglutinin and a-agglutinin, Saccharomyces cerevisiae sexual cell adhesion molecules.

Q9Z277	BAZ1B_MOUSE	Tyrosine-protein kinase BAZ1B	19092802	WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity.

Q86X52	CHSS1_HUMAN	Chondroitin sulfate synthase 1	11514575	Molecular cloning and expression of a human chondroitin synthase.

Q54DF1	ATPG_DICDI	ATP synthase subunit gamma, mitochondrial	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P32610	VATD_YEAST	V-type proton ATPase subunit D	11283612	Skp1 forms multiple protein complexes, including RAVE, a regulator of V-ATPase assembly.

Q9UBN7	HDAC6_HUMAN	Histone deacetylase 6	12620231	The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase.

Q8TBC4	UBA3_HUMAN	NEDD8-activating enzyme E1 catalytic subunit	19250909	E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification.

Q9UKK3	PARP4_HUMAN	Poly [ADP-ribose] polymerase 4	10100603	The nuclear protein PH5P of the inter-alpha-inhibitor superfamily: a missing link between poly(ADP-ribose)polymerase and the inter-alpha- inhibitor family and a novel actor of DNA repair?

P42260	GRIK2_RAT	Glutamate receptor, ionotropic kainate 2	1648177	Cloning of a cDNA for a glutamate receptor subunit activated by kainate but not AMPA.

P61327	MGN_MOUSE	Protein mago nashi homolog	9272960	Mago nashi mediates the posterior follicle cell-to-oocyte signal to organize axis formation in Drosophila.

P97584	PTGR1_RAT	Prostaglandin reductase 1	8968041	Isolation of cDNAs representing dithiolethione-responsive genes.

P51795	CLCN5_HUMAN	H(+)/Cl(-) exchange transporter 5	8559248	A common molecular basis for three inherited kidney stone diseases.

O80452	AMPD_ARATH	AMP deaminase	15918887	EMBRYONIC FACTOR 1 encodes an AMP deaminase and is essential for the zygote to embryo transition in Arabidopsis.

Q8BR76	MKS3_MOUSE	Meckelin	17185389	The Meckel-Gruber syndrome proteins MKS1 and meckelin interact and are required for primary cilium formation.

P51142	DVL2_XENLA	Segment polarity protein dishevelled homolog DVL-2	16362052	Dishevelled mediates ephrinB1 signalling in the eye field through the planar cell polarity pathway.

O75154	RFIP3_HUMAN	Rab11 family-interacting protein 3	17030804	Structural basis for Rab11-dependent membrane recruitment of a family of Rab11-interacting protein 3 (FIP3)/Arfophilin-1.

Q15365	PCBP1_HUMAN	Poly(rC)-binding protein 1	8152927	Tissue specific expression and cDNA structure of a human transcript encoding a nucleic acid binding [oligo(dC)] protein related to the pre-mRNA binding protein K.

P38241	SLT11_YEAST	Pre-mRNA-splicing factor SLT11	14562095	Global analysis of protein localization in budding yeast.

O35906	SPIB_MOUSE	Transcription factor Spi-B	11980719	Spi-B can functionally replace PU.1 in myeloid but not lymphoid development.

Q96CA5	BIRC7_HUMAN	Baculoviral IAP repeat-containing protein 7	11801603	SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP).

P39526	LAA1_YEAST	AP-1 accessory protein LAA1	14562095	Global analysis of protein localization in budding yeast.

Q00889	PSG6_HUMAN	Pregnancy-specific beta-1-glycoprotein 6	2271648	Characterization of two new members of the pregnancy-specific beta 1- glycoprotein family from the myeloid cell line KG-1 and suggestion of two distinct classes of transcription unit.

Q06136	KDSR_HUMAN	3-ketodihydrosphingosine reductase	8417785	FVT-1, a novel human transcription unit affected by variant translocation t(2;18)(p11;q21) of follicular lymphoma.

Q9NYJ7	DLL3_HUMAN	Delta-like protein 3	10742114	Mutations in the human delta homologue, DLL3, cause axial skeletal defects in spondylocostal dysostosis.

P60484	PTEN_HUMAN	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	9187108	TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta.

Q8VEM9	KLDC3_MOUSE	Kelch domain-containing protein 3	12606021	A novel testis-specific RAG2-like protein, Peas: its expression in pachytene spermatocyte cytoplasm and meiotic chromatin.

Q57984	SYA_METJA	Alanyl-tRNA synthetase	14663147	Trans-editing of mischarged tRNAs.

P23946	CMA1_HUMAN	Chymase	1894611	Cloning of the gene and cDNA for human heart chymase.

Q9GZX3	CHST6_HUMAN	Carbohydrate sulfotransferase 6	11181564	Chromosomal localization and genomic organization for the galactose/ N-acetylgalactosamine/N-acetylglucosamine 6-O-sulfotransferase gene family.

P27305	GLUQ_ECOLI	Glutamyl-Q tRNA(Asp) synthetase	15096594	An aminoacyl-tRNA synthetase-like protein encoded by the Escherichia coli yadB gene glutamylates specifically tRNAAsp.

Q13796	SHRM2_HUMAN	Protein Shroom2	7795590	Cloning of a human homologue of the Xenopus laevis APX gene from the ocular albinism type 1 critical region.

Q13332	PTPRS_HUMAN	Receptor-type tyrosine-protein phosphatase S	8524829	The LAR/PTP delta/PTP sigma subfamily of transmembrane protein- tyrosine-phosphatases: multiple human LAR, PTP delta, and PTP sigma isoforms are expressed in a tissue-specific manner and associate with the LAR-interacting protein LIP.1.

O15519	CFLAR_HUMAN	CASP8 and FADD-like apoptosis regulator	9208847	Casper is a FADD- and caspase-related inducer of apoptosis.

Q6IE62	PRS45_RAT	Inactive serine protease 45	15060002	A genomic analysis of rat proteases and protease inhibitors.

P43124	NSE4_YEAST	Non-structural maintenance of chromosome element 4	14562095	Global analysis of protein localization in budding yeast.

Q13769	THOC5_HUMAN	THO complex subunit 5 homolog	17190602	Human mRNA export machinery recruited to the 5' end of mRNA.

O22971	CIPKD_ARATH	CBL-interacting serine/threonine-protein kinase 13	11230129	The NAF domain defines a novel protein-protein interaction module conserved in Ca(2+)-regulated kinases.

Q15149	PLEC_HUMAN	Plectin	8633055	Human plectin: organization of the gene, sequence analysis, and chromosome localization (8q24).

O00258	WRB_HUMAN	Tryptophan-rich protein	9544840	Identification and characterization of a new human cDNA from chromosome 21q22.3 encoding a basic nuclear protein.

Q62666	VACHT_RAT	Vesicular acetylcholine transporter	8071310	Functional identification of a vesicular acetylcholine transporter and its expression from a 'cholinergic' gene locus.

P53597	SUCA_HUMAN	Succinyl-CoA ligase [GDP-forming] subunit alpha, mitochondrial	9128182	The molecular basis for cross-reaction anti-dystrophin antibody with alpha-actinin.

P86168	COLUA_COLDE	Colutellin-A	18599825	Colutellin A, an immunosuppressive peptide from Colletotrichum dematium.

Q9M8S8	VTC4_ARATH	Inositol-phosphate phosphatase	16595667	Arabidopsis thaliana VTC4 encodes L-galactose-1-P phosphatase, a plant ascorbic acid biosynthetic enzyme.

Q868Z9	PPN_DROME	Papilin	11076767	Papilin in development; a pericellular protein with a homology to the ADAMTS metalloproteinases.

Q9Y6R7	FCGBP_HUMAN	IgGFc-binding protein	19432394	Proteomic analyses of the two mucus layers of the colon barrier reveal that their main component, the Muc2 mucin, is strongly bound to the Fcgbp protein.

P23874	HIPA_ECOLI	Protein hipA	8021189	Autoregulation of hip, an operon that affects lethality due to inhibition of peptidoglycan or DNA synthesis.

Q9ERI5	JMJD6_MOUSE	Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6	15345036	The phosphatidylserine receptor has essential functions during embryogenesis but not in apoptotic cell removal.

Q11055	Y1264_MYCTU	pH-sensitive adenylate cyclase Rv1264	11839758	Adenylyl cyclase Rv1264 from Mycobacterium tuberculosis has an autoinhibitory N-terminal domain.

Q8BIA4	FBXW8_MOUSE	F-box/WD repeat-containing protein 8	16880526	Fbxw8 is essential for Cul1-Cul7 complex formation and for placental development.

Q9SLC3	ATL41_ARATH	E3 ubiquitin-protein ligase ATL41	16339806	Genome analysis and functional characterization of the E2 and RING- type E3 ligase ubiquitination enzymes of Arabidopsis.

Q8R2F2	DEGS2_MOUSE	Sphingolipid delta(4)-desaturase/C4-hydroxylase DES2	16571104	Dihydroceramide:sphinganine C-4-hydroxylation requires Des2 hydroxylase and the membrane form of cytochrome b5.

P53285	VPS62_YEAST	Vacuolar protein sorting-associated protein 62	12134085	Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae.

O04294	IMA2_ARATH	Importin subunit alpha-2	9765207	Pleiotropic control of glucose and hormone responses by PRL1, a nuclear WD protein, in Arabidopsis.

O43174	CP26A_HUMAN	Cytochrome P450 26A1	9716180	Human retinoic acid (RA) 4-hydroxylase (CYP26) is highly specific for all-trans-RA and can be induced through RA receptors in human breast and colon carcinoma cells.

P53260	GATF_YEAST	Glutamyl-tRNA(Gln) amidotransferase subunit F, mitochondrial	19417106	Yeast mitochondrial Gln-tRNA(Gln) is generated by a GatFAB-mediated transamidation pathway involving Arc1p-controlled subcellular sorting of cytosolic GluRS.

Q01892	SPIB_HUMAN	Transcription factor Spi-B	1406622	Characterization of Spi-B, a transcription factor related to the putative oncoprotein Spi-1/PU.1.

P60824	CIRBP_MOUSE	Cold-inducible RNA-binding protein	17967451	The cold-inducible RNA-binding protein migrates from the nucleus to cytoplasmic stress granules by a methylation-dependent mechanism and acts as a translational repressor.

P38145	RISA_YEAST	Riboflavin synthase alpha chain	7814407	Riboflavin biosynthesis in Saccharomyces cerevisiae. Cloning, characterization, and expression of the RIB5 gene encoding riboflavin synthase.

P78348	ACCN2_HUMAN	Amiloride-sensitive cation channel 2, neuronal	9037075	BNaC1 and BNaC2 constitute a new family of human neuronal sodium channels related to degenerins and epithelial sodium channels.

P53844	PDR17_YEAST	Phosphatidylinositol transfer protein PDR17	14562095	Global analysis of protein localization in budding yeast.

P25337	BUD31_YEAST	Bud site selection protein 31	11452010	A genomic study of the bipolar bud site selection pattern in Saccharomyces cerevisiae.

Q9V9J3	SRC42_DROME	Tyrosine-protein kinase Src42A	8682295	Regulation of cell-cell contacts in developing Drosophila eyes by Dsrc41, a new, close relative of vertebrate c-src.

Q7T1H5	DND1_DANRE	Dead end protein 1	12932328	Dead end, a novel vertebrate germ plasm component, is required for zebrafish primordial germ cell migration and survival.

Q9FWR4	DHAR1_ARATH	Glutathione S-transferase DHAR1, mitochondrial	16526091	Proteomic survey of copper-binding proteins in Arabidopsis roots by immobilized metal affinity chromatography and mass spectrometry.

Q62758	5HT4R_RAT	5-hydroxytryptamine receptor 4	7796807	The 5-HT4 receptor: molecular cloning and pharmacological characterization of two splice variants.

P08118	MSMB_HUMAN	Beta-microseminoprotein	7566962	Alternative splicing of PSP94 (prostatic secretory protein of 94 amino acids) mRNA in prostate tissue.

Q02742	GCNT1_HUMAN	Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase	1329093	Expression cloning of a cDNA encoding UDP-GlcNAc:Gal beta 1-3-GalNAc- R (GlcNAc to GalNAc) beta 1-6GlcNAc transferase by gene transfer into CHO cells expressing polyoma large tumor antigen.

P06756	ITAV_HUMAN	Integrin alpha-V	2430295	cDNA and amino acid sequences of the cell adhesion protein receptor recognizing vitronectin reveal a transmembrane domain and homologies with other adhesion protein receptors.

Q03834	MSH6_YEAST	DNA mismatch repair protein MSH6	14562095	Global analysis of protein localization in budding yeast.

Q8LE98	ICR1_ARATH	Interactor of constitutive active ROPs 1	17493810	A Novel ROP/RAC effector links cell polarity, root-meristem maintenance, and vesicle trafficking.

Q80UE6	WNK4_MOUSE	Serine/threonine-protein kinase WNK4	11498583	Human hypertension caused by mutations in WNK kinases.

P47164	MET7_YEAST	Cystathionine gamma-synthase	14562095	Global analysis of protein localization in budding yeast.

O00624	NPT3_HUMAN	Sodium-dependent phosphate transport protein 3	9149941	A 1.1-Mb transcript map of the hereditary hemochromatosis locus.

Q0P031	VSX1_XENLA	Visual system homeobox 1	16903786	Timing the generation of distinct retinal cells by homeobox proteins.

Q9VDE5	PPAN_DROME	Protein Peter pan	10359593	Cloning and characterization of peter pan, a novel Drosophila gene required for larval growth.

P42736	RAP23_ARATH	Ethylene-responsive transcription factor RAP2-3	9159183	Arabidopsis thaliana ethylene-responsive element binding protein (AtEBP), an ethylene-inducible, GCC box DNA-binding protein interacts with an ocs element binding protein.

O01427	AIR2_CAEEL	Aurora/IPL1-related protein kinase 2	12015116	The aurora B kinase AIR-2 regulates kinetochores during mitosis and is required for separation of homologous Chromosomes during meiosis.

P0AGE0	SSB_ECOLI	Single-stranded DNA-binding protein	2087220	The single-stranded DNA-binding protein of Escherichia coli.

Q15437	SC23B_HUMAN	Protein transport protein Sec23B	8898360	Cloning and functional characterization of mammalian homologues of the COPII component Sec23.

P07948	LYN_HUMAN	Tyrosine-protein kinase Lyn	18817770	Nuclear localization of Lyn tyrosine kinase mediated by inhibition of its kinase activity.

Q9V727	ASX_DROME	Polycomb protein Asx	9477319	The Additional sex combs gene of Drosophila encodes a chromatin protein that binds to shared and unique Polycomb group sites on polytene chromosomes.

O45876	APH1_CAEEL	Gamma-secretase subunit aph-1	11792846	APH-1 is a multipass membrane protein essential for the Notch signaling pathway in Caenorhabditis elegans embryos.

Q64581	CP3AI_RAT	Cytochrome P450 3A18	8845857	Isolation and characterization of a new rat P450 (CYP3A18) cDNA encoding P450(6)beta-2 catalyzing testosterone 6 beta- and 16 alpha- hydroxylations.

Q9SY55	ECA3_ARATH	Calcium-transporting ATPase 3, endoplasmic reticulum-type	18024560	ECA3, a Golgi-localized P2A-type ATPase, plays a crucial role in manganese nutrition in Arabidopsis.

Q6NPF9	TRXY1_ARATH	Thioredoxin Y1, chloroplastic	15531707	Characterization of plastidial thioredoxins from Arabidopsis belonging to the new y-type.

Q9JIS4	KCNKA_RAT	Potassium channel subfamily K member 10	10747911	TREK-2, a new member of the mechanosensitive tandem-pore K+ channel family.

O43278	SPIT1_HUMAN	Kunitz-type protease inhibitor 1	9045658	Hepatocyte growth factor activator inhibitor, a novel Kunitz-type serine protease inhibitor.

Q9VB08	RING1_DROME	E3 ubiquitin-protein ligase RING1	14669021	A proposed role for the Polycomb group protein dRING in meiotic sister-chromatid cohesion.

Q62976	KCMA1_RAT	Calcium-activated potassium channel subunit alpha-1	10384881	Identification and localization of Ca(2+)-activated K+ channels in rat sciatic nerve.

P05764	RS21_SCHPO	40S ribosomal protein S21	14623272	Ribosomal proteins S0 and S21 are involved in the stability of 18S rRNA in fission yeast, Schizosaccharomyces pombe.

P32011	DRRB_STRPE	Daunorubicin/doxorubicin resistance ABC transporter permease protein drrB	9006006	Expression and characterization of DrrA and DrrB proteins of Streptomyces peucetius in Escherichia coli: DrrA is an ATP binding protein.

Q9LEX0	P2A13_ARATH	F-box protein PP2-A13	12795696	Protein interaction analysis of SCF ubiquitin E3 ligase subunits from Arabidopsis.

Q9UPN3	MACF1_HUMAN	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5	10559237	Molecular cloning and characterization of human trabeculin-alpha, a giant protein defining a new family of actin-binding proteins.

P53292	RT35_YEAST	37S ribosomal protein S35, mitochondrial	12392552	Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components.

P35436	NMDE1_MOUSE	Glutamate [NMDA] receptor subunit epsilon-1	1374164	Functional characterization of a heteromeric NMDA receptor channel expressed from cloned cDNAs.

Q17820	SAE1_CAEEL	SUMO-activating enzyme subunit aos-1	15107848	SUMO modification is required for in vivo Hox gene regulation by the Caenorhabditis elegans Polycomb group protein SOP-2.

P05997	CO5A2_HUMAN	Collagen alpha-2(V) chain	9783710	A single base mutation in COL5A2 causes Ehlers-Danlos syndrome type II.

P19357	GTR4_RAT	Solute carrier family 2, facilitated glucose transporter member 4	9059504	Characterization of rat Glut4 glucose transporter expressed in the yeast Saccharomyces cerevisiae: comparison with Glut1 glucose transporter.

Q9BYG3	MK67I_HUMAN	MKI67 FHA domain-interacting nucleolar phosphoprotein	11342549	A novel nucleolar protein, NIFK, interacts with the forkhead associated domain of Ki-67 antigen in mitosis.

O43001	SYJ1_SCHPO	Inositol-1,4,5-trisphosphate 5-phosphatase 1	15316017	Comparative mechanistic and substrate specificity study of inositol polyphosphate 5-phosphatase Schizosaccharomyces pombe Synaptojanin and SHIP2.

P30938	SSR5_RAT	Somatostatin receptor type 5	1362243	Molecular cloning and expression of a pituitary somatostatin receptor with preferential affinity for somatostatin-28.

P84646	SCX1_ODODO	Alpha-toxin OD1	16038905	OD1, the first toxin isolated from the venom of the scorpion Odonthobuthus doriae active on voltage-gated Na+ channels.

P52034	K6PF_DROME	6-phosphofructokinase	7929140	Structure and expression of the gene encoding phosphofructokinase (PFK) in Drosophila melanogaster.

O94782	UBP1_HUMAN	Ubiquitin carboxyl-terminal hydrolase 1	9806842	Identification and chromosomal assignment of USP1, a novel gene encoding a human ubiquitin-specific protease.

Q02785	PDR12_YEAST	ATP-dependent permease PDR12	9687494	The pdr12 ABC transporter is required for the development of weak organic acid resistance in yeast.

P23527	H2B1O_HUMAN	Histone H2B type 1-O	1768865	A novel divergently transcribed human histone H2A/H2B gene pair.

O14836	TR13B_HUMAN	Tumor necrosis factor receptor superfamily member 13B	9311921	NF-AT activation induced by a CAML-interacting member of the tumor necrosis factor receptor superfamily.

O59715	DEGS_SCHPO	Dihydroceramide delta(4)-desaturase	12633877	The dihydroceramide desaturase is not essential for cell viability in Schizosaccharomyces pombe.

P00533	EGFR_HUMAN	Epidermal growth factor receptor	2790960	Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation.

P38956	SNF11_YEAST	Transcription regulatory protein SNF11	7623818	SNF11, a new component of the yeast SNF-SWI complex that interacts with a conserved region of SNF2.

Q9HBF4	ZFYV1_HUMAN	Zinc finger FYVE domain-containing protein 1	11256955	Characterization of a novel phosphatidylinositol 3-phosphate-binding protein containing two FYVE fingers in tandem that is targeted to the Golgi.

O15318	RPC7_HUMAN	DNA-directed RNA polymerase III subunit RPC7	9171375	Three human RNA polymerase III-specific subunits form a subcomplex with a selective function in specific transcription initiation.

Q99623	PHB2_HUMAN	Prohibitin-2	11302691	Mammalian prohibitin proteins respond to mitochondrial stress and decrease during cellular senescence.

Q9U572	CLOT_PENMO	Hemolymph clottable protein	10561606	Molecular cloning and characterization of a hemolymph clottable protein from tiger shrimp (Penaeus monodon).

A0JC51	ZIC4_XENLA	Zinc finger protein ZIC 4	16871625	Xenopus Zic4: conservation and diversification of expression profiles and protein function among the Xenopus Zic family.

Q9Y2Z4	SYYM_HUMAN	Tyrosyl-tRNA synthetase, mitochondrial	15779907	Toward the full set of human mitochondrial aminoacyl-tRNA synthetases: characterization of AspRS and TyrRS.

Q9UHD8	SEPT9_HUMAN	Septin-9	15485874	Biochemical and cell biological analyses of a mammalian septin complex, Sept7/9b/11.

Q42374	SY111_ARATH	Syntaxin-related protein KNOLLE	9396754	The Arabidopsis KNOLLE protein is a cytokinesis-specific syntaxin.

Q14643	ITPR1_HUMAN	Inositol 1,4,5-trisphosphate receptor type 1	7852357	The human type 1 inositol 1,4,5-trisphosphate receptor from T lymphocytes. Structure, localization, and tyrosine phosphorylation.

Q9QXT4	CMLO1_RAT	Probable N-acetyltransferase CML1	11397015	Overexpression of camello, a member of a novel protein family, reduces blastomere adhesion and inhibits gastrulation in Xenopus laevis.

Q99583	MNT_HUMAN	Max-binding protein MNT	9184233	Rox, a novel bHLHZip protein expressed in quiescent cells that heterodimerizes with Max, binds a non-canonical E box and acts as a transcriptional repressor.

Q86UW6	N4BP2_HUMAN	NEDD4-binding protein 2	12730195	Identification and characterization of BCL-3-binding protein: implications for transcription and DNA repair or recombination.

P53153	YGI5_YEAST	Probable endonuclease YGL085W	14562095	Global analysis of protein localization in budding yeast.

Q9Y616	IRAK3_HUMAN	Interleukin-1 receptor-associated kinase 3	10383454	IRAK-M is a novel member of the Pelle/interleukin-1 receptor- associated kinase (IRAK) family.

O95396	MOCS3_HUMAN	Adenylyltransferase and sulfurtransferase MOCS3	15073332	Evidence for the physiological role of a rhodanese-like protein for the biosynthesis of the molybdenum cofactor in humans.

P27521	CA4_ARATH	Chlorophyll a-b binding protein 4, chloroplastic	12766230	Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.

Q39103	G3OX1_ARATH	Gibberellin 3-beta-dioxygenase 1	9625708	Function and substrate specificity of the gibberellin 3beta- hydroxylase encoded by the Arabidopsis GA4 gene.

Q9SHE7	RUB1_ARATH	Ubiquitin-NEDD8-like protein RUB1	9624055	The ubiquitin-related protein RUB1 and auxin response in Arabidopsis.

Q93Y23	GSOX4_ARATH	Flavin-containing monooxygenase FMO GS-OX4	18799661	Subclade of flavin-monooxygenases involved in aliphatic glucosinolate biosynthesis.

Q54XS1	PH4H_DICDI	Phenylalanine-4-hydroxylase	18835579	The phylogeny of the aromatic amino acid hydroxylases revisited by characterizing phenylalanine hydroxylase from Dictyostelium discoideum.

Q9ER65	CSTN2_MOUSE	Calsyntenin-2	12498782	The calsyntenins - a family of postsynaptic membrane proteins with distinct neuronal expression patterns.

Q9LZR5	HDT3_ARATH	Histone deacetylase HDT3	16553900	Identification of AtHD2C as a novel regulator of abscisic acid responses in Arabidopsis.

P36528	RM17_YEAST	54S ribosomal protein L17, mitochondrial	12392552	Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components.

Q03135	CAV1_HUMAN	Caveolin-1	15219854	N-terminal processing and modifications of caveolin-1 in caveolae from human adipocytes.

O77438	FRIZ3_DROME	Frizzled-3	10498678	Dfrizzled-3, a new Drosophila Wnt receptor, acting as an attenuator of Wingless signaling in wingless hypomorphic mutants.

Q91399	ID3A_XENLA	DNA-binding protein inhibitor ID-3-A	14651922	Cloning and characterization of Xenopus Id4 reveals differing roles for Id genes.

O94537	PPK4_SCHPO	Serine/threonine-protein kinase ppk4	15821139	Systematic deletion analysis of fission yeast protein kinases.

Q9UBV8	PEF1_HUMAN	Peflin	10486255	Peflin, a novel member of the five-EF-hand-protein family, is similar to the apoptosis-linked gene 2 (ALG-2) protein but possesses nonapeptide repeats in the N-terminal hydrophobic region.

Q94B77	FH5_ARATH	Formin-like protein 5	15765105	Plant formin AtFH5 is an evolutionarily conserved actin nucleator involved in cytokinesis.

P34278	KNL1_CAEEL	Kinetochore null protein 1	14522947	KNL-1 directs assembly of the microtubule-binding interface of the kinetochore in C. elegans.

Q9Y794	ORC4_SCHPO	Origin recognition complex subunit 4	11850415	Purification and characterization of the Schizosaccharomyces pombe origin recognition complex: interaction with origin DNA and Cdc18 protein.

Q9JLH7	CK5P3_RAT	CDK5 regulatory subunit-associated protein 3	10721722	Cloning of three novel neuronal Cdk5 activator binding proteins.

P50224	ST1A3_HUMAN	Sulfotransferase 1A3/1A4	8363592	Identification of two human brain aryl sulfotransferase cDNAs.

P03905	NU4M_HUMAN	NADH-ubiquinone oxidoreductase chain 4	3921850	Six unidentified reading frames of human mitochondrial DNA encode components of the respiratory-chain NADH dehydrogenase.

O95232	LC7L3_HUMAN	Luc7-like protein 3	19574390	Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing.

Q94BM7	SPA4_ARATH	Protein SPA1-RELATED 4	12887588	The SPA1-like proteins SPA3 and SPA4 repress photomorphogenesis in the light.

P35605	COPB2_BOVIN	Coatomer subunit beta'	8334999	Beta'-COP, a novel subunit of coatomer.

P32322	P5CR1_HUMAN	Pyrroline-5-carboxylate reductase 1, mitochondrial	19648921	Mutations in PYCR1 cause cutis laxa with progeroid features.

Q29980	MICB_HUMAN	MHC class I polypeptide-related sequence B	11287116	Oxidative stress increases MICA and MICB gene expression in the human colon carcinoma cell line (CaCo-2).

P26583	HMGB2_HUMAN	High mobility group protein B2	11909973	HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A.

Q9ZNU2	NAC18_ARATH	NAC domain-containing protein 18	12175016	Molecular characterization of AtNAM: a member of the Arabidopsis NAC domain superfamily.

Q92351	PCP1_SCHPO	Spindle pole body protein pcp1	11864908	Pcp1p, a Spc110p-related calmodulin target at the centrosome of the fission yeast Schizosaccharomyces pombe.

P01774	HV313_HUMAN	Ig heavy chain V-III region POM	4139708	Structure of antibodies with shared idiotypy: the complete sequence of the heavy chain variable regions of two immunoglobulin M anti-gamma globulins.

Q12499	NOP58_YEAST	Nucleolar protein 58	12068309	A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis.

P30793	GCH1_HUMAN	GTP cyclohydrolase 1	7874165	Hereditary progressive dystonia with marked diurnal fluctuation caused by mutations in the GTP cyclohydrolase I gene.

Q5Y4Y6	GSDA3_MOUSE	Gasdermin-A3	15737203	Mutations in gasdermin 3 cause aberrant differentiation of the hair follicle and sebaceous gland.

O74878	ALG11_SCHPO	Alpha-1,2-mannosyltransferase alg11	11015724	Schizosaccharomyces pombe gmd3(+)/alg11(+) is a functional homologue of Saccharomyces cerevisiae ALG11 which is involved in N-linked oligosaccharide synthesis.

Q9UHP9	SMPX_HUMAN	Small muscular protein	10598820	Identification, mapping, and genomic structure of a novel X- chromosomal human gene (SMPX) encoding a small muscular protein.

O14827	RGRF2_HUMAN	Ras-specific guanine nucleotide-releasing factor 2	10373510	Ras-specific exchange factor GRF: oligomerization through its Dbl homology domain and calcium-dependent activation of Raf.

Q6P6N5	SPRE3_MOUSE	Sprouty-related, EVH1 domain-containing protein 3	12646235	Molecular cloning of mammalian Spred-3 which suppresses tyrosine kinase-mediated Erk activation.

O13706	YEU7_SCHPO	Uncharacterized protein C13F5.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9SZF7	SHR_ARATH	Protein SHORT-ROOT	17446396	An evolutionarily conserved mechanism delimiting SHR movement defines a single layer of endodermis in plants.

Q8CIS0	CAR11_MOUSE	Caspase recruitment domain-containing protein 11	12356734	CARD11 mediates factor-specific activation of NF-kappaB by the T cell receptor complex.

P46310	FAD3C_ARATH	Omega-3 fatty acid desaturase, chloroplastic	12766230	Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.

P62701	RS4X_HUMAN	40S ribosomal protein S4, X isoform	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

P38418	LOX2_ARATH	Lipoxygenase 2, chloroplastic	7567995	A chloroplast lipoxygenase is required for wound-induced jasmonic acid accumulation in Arabidopsis.

Q9VKJ7	GR32A_DROME	Putative gustatory receptor 32a	10710312	Candidate taste receptors in Drosophila.

Q12143	NSL1_YEAST	Kinetochore-associated protein NSL1	12455957	Nnf1p, Dsn1p, Mtw1p, and Nsl1p: a new group of proteins important for chromosome segregation in Saccharomyces cerevisiae.

P04844	RPN2_HUMAN	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2	15835887	Proteomic analysis of mammalian oligosaccharyltransferase reveals multiple subcomplexes that contain Sec61, TRAP, and two potential new subunits.

Q62968	SCNAA_RAT	Sodium channel protein type 10 subunit alpha	12050667	Annexin II light chain regulates sensory neuron-specific sodium channel expression.

P90794	DCA11_CAEEL	DDB1- and CUL4-associated factor 11 homolog	17411345	Lifespan regulation by evolutionarily conserved genes essential for viability.

P85876	ETCM_ENTFC	Bacteriocin enterocin-M	17551760	Isolation and characterization of a new bacteriocin, termed enterocin M, produced by environmental isolate Enterococcus faecium AL41.

P57727	TMPS3_HUMAN	Transmembrane protease serine 3	11137999	Insertion of beta-satellite repeats identifies a transmembrane protease causing both congenital and childhood onset autosomal recessive deafness.

P42657	RAD25_SCHPO	DNA damage checkpoint protein rad25	8036497	14-3-3 protein homologs required for the DNA damage checkpoint in fission yeast.

Q5HV71	RS16_CAMJR	30S ribosomal protein S16	15660156	Major structural differences and novel potential virulence mechanisms from the genomes of multiple Campylobacter species.

P23763	VAMP1_HUMAN	Vesicle-associated membrane protein 1	1976629	Structures and chromosomal localizations of two human genes encoding synaptobrevins 1 and 2.

Q9W705	NCOA2_XENLA	Nuclear receptor coactivator 2	10704837	XTIF2, a Xenopus homologue of the human transcription intermediary factor, is required for a nuclear receptor pathway that also interacts with CBP to suppress Brachyury and XMyoD.

A8CVX7	TTLL6_DANRE	Tubulin polyglutamylase ttll6	17761526	The zebrafish fleer gene encodes an essential regulator of cilia tubulin polyglutamylation.

O43918	AIRE_HUMAN	Autoimmune regulator	9398840	An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains.

Q9UKG1	DP13A_HUMAN	DCC-interacting protein 13-alpha	12011067	Mediation of the DCC apoptotic signal by DIP13 alpha.

Q9P032	NDUF4_HUMAN	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4	19463981	Mutations in NDUFAF3 (C3ORF60), encoding an NDUFAF4 (C6ORF66)- interacting complex I assembly protein, cause fatal neonatal mitochondrial disease.

Q61188	EZH2_MOUSE	Histone-lysine N-methyltransferase EZH2	15520282	The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation.

P31120	GLMM_ECOLI	Phosphoglucosamine mutase	8550580	Characterization of the essential gene glmM encoding phosphoglucosamine mutase in Escherichia coli.

O74718	ERF3_SCHPO	Eukaryotic peptide chain release factor GTP-binding subunit	9701287	The stretch of C-terminal acidic amino acids of translational release factor eRF1 is a primary binding site for eRF3 of fission yeast.

P13574	STE12_YEAST	Protein STE12	2558054	STE12, a protein involved in cell-type-specific transcription and signal transduction in yeast, is part of protein-DNA complexes.

Q9Y7S4	YQO5_SCHPO	Uncharacterized transporter C569.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8GYQ5	MPK12_ARATH	Mitogen-activated protein kinase 12	19000167	Arabidopsis mitogen-activated protein kinase MPK12 interacts with the MAPK phosphatase IBR5 and regulates auxin signaling.

Q02224	CENPE_HUMAN	Centromere-associated protein E	7889940	Mitotic HeLa cells contain a CENP-E-associated minus end-directed microtubule motor.

Q06S87	HIUH_DANRE	5-hydroxyisourate hydrolase	16952372	Structure of zebra fish HIUase: insights into evolution of an enzyme to a hormone transporter.

Q8BXG3	IFT57_MOUSE	Intraflagellar transport protein 57 homolog	11788820	Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi.

P30860	ARTJ_ECOLI	ABC transporter arginine-binding protein 1	8801422	A third periplasmic transport system for L-arginine in Escherichia coli: molecular characterization of the artPIQMJ genes, arginine binding and transport.

P32684	RLUF_ECOLI	Ribosomal large subunit pseudouridine synthase F	11720289	Identification and site of action of the remaining four putative pseudouridine synthases in Escherichia coli.

P01185	NEU2_HUMAN	Vasopressin-neurophysin 2-copeptin	1740104	A missense mutation in the vasopressin-neurophysin precursor gene cosegregates with human autosomal dominant neurohypophyseal diabetes insipidus.

Q9XIK3	ISCAP_ARATH	Iron-sulfur assembly protein IscA, chloroplastic	15888686	Iron-sulfur cluster biogenesis in chloroplasts. Involvement of the scaffold protein CpIscA.

Q8K1G0	ACAM_RAT	Adipocyte adhesion molecule	15563274	Identification of adipocyte adhesion molecule (ACAM), a novel CTX gene family, implicated in adipocyte maturation and development of obesity.

P29590	PML_HUMAN	Probable transcription factor PML	9570750	Ret finger protein is a normal component of PML nuclear bodies and interacts directly with PML.

Q63470	DYR1A_RAT	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	9748265	Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases.

Q9BV90	SNR25_HUMAN	U11/U12 small nuclear ribonucleoprotein 25 kDa protein	15146077	The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome.

P51610	HCFC1_HUMAN	Host cell factor 1	10976766	A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening.

Q9BT25	HAUS8_HUMAN	HAUS augmin-like complex subunit 8	19369198	The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells.

P82869	CYP37_ARATH	Peptidyl-prolyl cis-trans isomerase CYP37, chloroplastic	11719511	Proteome map of the chloroplast lumen of Arabidopsis thaliana.

P53313	SDA1_YEAST	Protein SDA1	15107621	The yeast kinase Swe1 is required for proper entry into cell cycle after arrest due to ribosome biogenesis and protein synthesis defects.

P40394	ADH7_HUMAN	Alcohol dehydrogenase class 4 mu/sigma chain	9228021	X-ray structure of human class IV sigmasigma alcohol dehydrogenase. Structural basis for substrate specificity.

A0S865	NXACB_BOIIR	Irditoxin subunit B	18952712	Irditoxin, a novel covalently linked heterodimeric three-finger toxin with high taxon-specific neurotoxicity.

B7ZQJ9	GT2D1_XENLA	General transcription factor II-I repeat domain-containing protein 1	11937490	The role of a Williams-Beuren syndrome-associated helix-loop-helix domain-containing transcription factor in activin/nodal signaling.

P49747	COMP_HUMAN	Cartilage oligomeric matrix protein	16051604	Cartilage oligomeric matrix protein/thrombospondin 5 supports chondrocyte attachment through interaction with integrins.

Q9H1A4	APC1_HUMAN	Anaphase-promoting complex subunit 1	16364912	Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C.

Q9Y2B0	CNPY2_HUMAN	Protein canopy homolog 2	12826659	MSAP is a novel MIR-interacting protein that enhances neurite outgrowth and increases myosin regulatory light chain.

Q99645	EPYC_HUMAN	Epiphycan	8975717	Characterization of human DSPG3, a small dermatan sulfate proteoglycan.

Q96LA8	ANM6_HUMAN	Protein arginine N-methyltransferase 6	18079182	PRMT6-mediated methylation of R2 in histone H3 antagonizes H3 K4 trimethylation.

O43809	CPSF5_HUMAN	Cleavage and polyadenylation specificity factor subunit 5	15169763	Distinct sequence motifs within the 68-kDa subunit of cleavage factor Im mediate RNA binding, protein-protein interactions, and subcellular localization.

P27934	AMY3E_ORYSJ	Alpha-amylase isozyme 3E	2263460	Structural organization and differential expression of rice alpha- amylase genes.

Q15811	ITSN1_HUMAN	Intersectin-1	12006984	Structural basis for the selective activation of Rho GTPases by Dbl exchange factors.

Q13630	FCL_HUMAN	GDP-L-fucose synthase	8910301	Synthesis of GDP-L-fucose by the human FX protein.

Q8I8V0	TAD2B_DROME	Transcriptional adapter 2B	12697829	Two Drosophila Ada2 homologues function in different multiprotein complexes.

Q8LPQ9	FPA_ARATH	Flowering time control protein FPA	17916737	Widespread role for the flowering-time regulators FCA and FPA in RNA- mediated chromatin silencing.

P32828	SLX5_YEAST	E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5	11139495	Requirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiae.

Q3B724	CALS5_ARATH	Callose synthase 5	15842618	Callose synthase (CalS5) is required for exine formation during microgametogenesis and for pollen viability in Arabidopsis.

O14786	NRP1_HUMAN	Neuropilin-1	9288753	Neuropilin is a receptor for the axonal chemorepellent semaphorin III.

Q9Z286	ADCYA_RAT	Adenylate cyclase type 10	9874775	Cytosolic adenylyl cyclase defines a unique signaling molecule in mammals.

O14924	RGS12_HUMAN	Regulator of G-protein signaling 12	10869340	Novel alternative splicing and nuclear localization of human RGS12 gene products.

P81182	BGBP_LITVA	Beta-1,3-glucan-binding protein	9149399	Purification and comparison of beta-1,3-glucan binding protein from white shrimp (Penaeus vannamei).

P0A1E7	CSGA_SALEN	Major curlin subunit	17379722	AgfC and AgfE facilitate extracellular thin aggregative fimbriae synthesis in Salmonella enteritidis.

Q8QG92	DCT1B_XENLA	Dapper 1-B	11970895	Dapper, a Dishevelled-associated antagonist of beta-catenin and JNK signaling, is required for notochord formation.

O61122	SVKA_DICDI	Serine/threonine-protein kinase svkA	9582328	Characterization and cloning of a Dictyostelium Ste20-like protein kinase that phosphorylates the actin-binding protein severin.

Q9Y297	FBW1A_HUMAN	F-box/WD repeat-containing protein 1A	12820959	Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase.

Q13231	CHIT1_HUMAN	Chitotriosidase-1	9748235	The human chitotriosidase gene. Nature of inherited enzyme deficiency.

Q9JHS3	MAPIP_MOUSE	Mitogen-activated protein-binding protein-interacting protein	15263099	Crystal structure of the p14/MP1 scaffolding complex: how a twin couple attaches mitogen-activated protein kinase signaling to late endosomes.

Q9BRA2	TXD17_HUMAN	Thioredoxin domain-containing protein 17	15355959	Structural basis of cellular redox regulation by human TRP14.

Q6X5Y6	WRI1_ARATH	Ethylene-responsive transcription factor WRI1	16553903	A spatiotemporal analysis of enzymatic activities associated with carbon metabolism in wild-type and mutant embryos of Arabidopsis using in situ histochemistry.

Q01469	FABP5_HUMAN	Fatty acid-binding protein, epidermal	1512466	Molecular cloning and expression of a novel keratinocyte protein (psoriasis-associated fatty acid-binding protein [PA-FABP]) that is highly up-regulated in psoriatic skin and that shares similarity to fatty acid-binding proteins.

Q02159	UBC7_YEAST	Ubiquitin-conjugating enzyme E2 7	16179953	Ubx2 links the Cdc48 complex to ER-associated protein degradation.

P61160	ARP2_HUMAN	Actin-related protein 2	9230079	The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly.

Q03774	TRM82_YEAST	tRNA (guanine-N(7)-)-methyltransferase subunit TRM82	17382321	RNA recognition mechanism of eukaryote tRNA (m7G46) methyltransferase (Trm8-Trm82 complex).

P40645	SOX6_MOUSE	Transcription factor SOX-6	14530442	Sox6 regulation of cardiac myocyte development.

Q9ES83	POPD1_MOUSE	Blood vessel epicardial substance	20057356	Identification of a novel Bves function: regulation of vesicular transport.

O75469	NR1I2_HUMAN	Nuclear receptor subfamily 1 group I member 2	9784494	SXR, a novel steroid and xenobiotic-sensing nuclear receptor.

Q9P7M9	RIB1_SCHPO	Probable GTP cyclohydrolase-2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UNE7	CHIP_HUMAN	E3 ubiquitin-protein ligase CHIP	10330192	Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions.

P25713	MT3_HUMAN	Metallothionein-3	1873033	The growth inhibitory factor that is deficient in the Alzheimer's disease brain is a 68 amino acid metallothionein-like protein.

Q9P2D7	DYH1_HUMAN	Dynein heavy chain 1, axonemal	9373155	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

O74886	YQE2_SCHPO	Uncharacterized protein C576.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q96QU1	PCD15_HUMAN	Protocadherin-15	14570705	PCDH15 is expressed in the neurosensory epithelium of the eye and ear and mutant alleles are responsible for both USH1F and DFNB23.

Q10666	POP1_CAEEL	Protein pop-1	10380924	WRM-1 activates the LIT-1 protein kinase to transduce anterior/posterior polarity signals in C. elegans.

Q9GZY6	NTAL_HUMAN	Linker for activation of T-cells family member 2	14722116	The importance of three membrane-distal tyrosines in the adaptor protein NTAL/LAB.

Q92608	DOCK2_HUMAN	Dedicator of cytokinesis protein 2	12176041	DOCK2 mediates T cell receptor-induced activation of Rac2 and IL-2 transcription.

P33201	MRT4_YEAST	mRNA turnover protein 4	10471698	Temperature-sensitive mutations in the Saccharomyces cerevisiae MRT4, GRC5, SLA2 and THS1 genes result in defects in mRNA turnover.

Q14004	CDK13_HUMAN	Cell division protein kinase 13	1731328	Cloning and antisense oligodeoxynucleotide inhibition of a human homolog of cdc2 required in hematopoiesis.

Q90Z12	HES4A_XENLA	Transcription factor HES-4-A	10976052	Hes6 acts in a positive feedback loop with the neurogenins to promote neuronal differentiation.

Q04049	POLH_YEAST	DNA polymerase eta	10932195	Efficient and accurate replication in the presence of 7,8-dihydro-8- oxoguanine by DNA polymerase eta.

P43069	CDC25_CANAL	Cell division control protein 25	8477693	A Candida albicans homolog of CDC25 is functional in Saccharomyces cerevisiae.

Q42538	SAT5_ARATH	Serine acetyltransferase 5	9830017	Isoform-dependent differences in feedback regulation and subcellular localization of serine acetyltransferase involved in cysteine biosynthesis from Arabidopsis thaliana.

Q9VLT5	POE_DROME	Protein purity of essence	9813038	Retinal targets for calmodulin include proteins implicated in synaptic transmission.

Q38HM4	TRI63_MOUSE	E3 ubiquitin-protein ligase TRIM63	15601779	Muscle-specific RING finger 1 is a bona fide ubiquitin ligase that degrades cardiac troponin I.

Q9US51	MTF1_SCHPO	Mitochondrial transcription factor 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q86U44	MTA70_HUMAN	N6-adenosine-methyltransferase 70 kDa subunit	9409616	Purification and cDNA cloning of the AdoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase.

Q09823	REC10_SCHPO	Meiotic recombination protein rec10	7586030	Molecular cloning of the meiosis-induced rec10 gene of Schizosaccharomyces pombe.

P48432	SOX2_MOUSE	Transcription factor SOX-2	7590241	Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3.

Q16181	SEPT7_HUMAN	Septin-7	15485874	Biochemical and cell biological analyses of a mammalian septin complex, Sept7/9b/11.

P62308	RUXG_HUMAN	Small nuclear ribonucleoprotein G	11574479	Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein.

P32916	SRPR_YEAST	Signal recognition particle receptor subunit alpha homolog	12654246	Structural basis for the function of the beta subunit of the eukaryotic signal recognition particle receptor.

P26439	3BHS2_HUMAN	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2	1944309	Structure and expression of a new complementary DNA encoding the almost exclusive 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4- isomerase in human adrenals and gonads.

Q2XU92	ACBG2_MOUSE	Long-chain-fatty-acid--CoA ligase ACSBG2	16371355	The second member of the human and murine 'bubblegum' family is a testis-and brainstem-specific acyl-CoA synthetase.

Q09917	PKD2_SCHPO	TRP-like ion channel pkd2	15537393	A microbial TRP-like polycystic-kidney-disease-related ion channel gene.

Q8RXV3	P2C59_ARATH	Probable protein phosphatase 2C 59	18266921	Arabidopsis proteins important for modulating defense responses to Pseudomonas syringae that secrete HopW1-1.

Q01082	SPTB2_HUMAN	Spectrin beta chain, brain 1	15262991	Ankyrin-B targets beta2-spectrin to an intracellular compartment in neonatal cardiomyocytes.

Q3UYI5	RGL3_MOUSE	Ral guanine nucleotide dissociation stimulator-like 3	10869344	A novel RalGEF-like protein, RGL3, as a candidate effector for rit and Ras.

Q90X64	VNG2A_XENLA	Vang-like protein 2-A	11780127	The planar cell-polarity gene stbm regulates cell behaviour and cell fate in vertebrate embryos.

Q8WZ42	TITIN_HUMAN	Titin	9804419	Structural basis for activation of the titin kinase domain during myofibrillogenesis.

P84712	TRIN1_HYPSU	Trypsin inhibitor HSTI	15142539	A novel 8.7 kDa protease inhibitor from chan seeds (Hyptis suaveolens L.) inhibits proteases from the larger grain borer Prostephanus truncatus (Coleoptera: Bostrichidae).

O94296	YOOC_SCHPO	Probable phospholipid-transporting ATPase C887.12	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P41143	OPRD_HUMAN	Delta-type opioid receptor	7808419	The human delta-opioid receptor: genomic organization, cDNA cloning, functional expression, and distribution in human brain.

O65282	CH10C_ARATH	20 kDa chaperonin, chloroplastic	12766230	Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.

P34125	DGKA_DICDI	Diacylglycerol kinase A	16042397	Analysis of a novel diacylglycerol kinase from Dictyostelium discoideum: DGKA.

O57474	CXA1_DANRE	Gap junction alpha-1 protein	15649473	Mutations in connexin43 (GJA1) perturb bone growth in zebrafish fins.

Q99MK2	KAT5_RAT	Histone acetyltransferase KAT5	19282473	Fe65 is required for Tip60-directed histone H4 acetylation at DNA strand breaks.

Q80XB4	NRAP_MOUSE	Nebulin-related-anchoring protein	9295142	Complete cDNA sequence and tissue localization of N-RAP, a novel nebulin-related protein of striated muscle.

Q54S40	GBPD_DICDI	Cyclic GMP-binding protein D	15827084	RasGEF-containing proteins GbpC and GbpD have differential effects on cell polarity and chemotaxis in Dictyostelium.

Q9NPC3	CIP1_HUMAN	E3 ubiquitin-protein ligase CCNB1IP1	12612082	A novel RING finger protein, human enhancer of invasion 10, alters mitotic progression through regulation of cyclin B levels.

Q13508	NAR3_HUMAN	Ecto-ADP-ribosyltransferase 3	9119374	Two novel human members of an emerging mammalian gene family related to mono-ADP-ribosylating bacterial toxins.

Q9Y6K0	CEPT1_HUMAN	Choline/ethanolaminephosphotransferase 1	10191259	Cloning and expression of a human choline/ethanolaminephosphotransferase: synthesis of phosphatidylcholine and phosphatidylethanolamine.

Q5VYS8	TUT7_HUMAN	Terminal uridylyltransferase 7	18172165	Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'.

Q9S9V0	CDPKV_ARATH	Calcium-dependent protein kinase 31	16307367	Identification of NPR1-dependent and independent genes early induced by salicylic acid treatment in Arabidopsis.

Q9P7W8	RSC9_SCHPO	Chromatin structure-remodeling complex subunit rsc9	18622392	Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast.

P84883	NETNE_TRYCR	GPI-anchored glycoprotein NETNES	15649890	Structural characterization of NETNES, a novel glycoconjugate in Trypanosoma cruzi epimastigotes.

P50232	SYT4_RAT	Synaptotagmin-4	7993622	Functional properties of multiple synaptotagmins in brain.

Q9WTW1	GRIP2_RAT	Glutamate receptor-interacting protein 2	10436050	Characterization of the glutamate receptor-interacting proteins GRIP1 and GRIP2.

O60427	FADS1_HUMAN	Fatty acid desaturase 1	10601301	Cloning, expression, and fatty acid regulation of the human Delta-5 desaturase.

Q9T041	MAPT_ARATH	Microtubule-associated protein TORTIFOLIA1	15324671	Helical growth of the Arabidopsis mutant tortifolia1 reveals a plant- specific microtubule-associated protein.

P61916	NPC2_HUMAN	Epididymal secretory protein E1	16548883	Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection.

Q12366	NDJ1_YEAST	Non-disjunction protein 1	18585352	Rapid telomere movement in meiotic prophase is promoted by NDJ1, MPS3, and CSM4 and is modulated by recombination.

P42787	CBPD_DROME	Carboxypeptidase D	12393882	Characterization of Drosophila carboxypeptidase D.

P38115	ARA1_YEAST	D-arabinose dehydrogenase [NAD(P)+] heavy chain	9920381	D-arabinose dehydrogenase and its gene from Saccharomyces cerevisiae.

P97452	BOP1_MOUSE	Ribosome biogenesis protein BOP1	17353269	Interdependence of Pes1, Bop1, and WDR12 controls nucleolar localization and assembly of the PeBoW complex required for maturation of the 60S ribosomal subunit.

O75832	PSD10_HUMAN	26S proteasome non-ATPase regulatory subunit 10	11900540	Novel insights into the INK4-CDK4/6-Rb pathway: counter action of gankyrin against INK4 proteins regulates the CDK4-mediated phosphorylation of Rb.

P49777	ABP1_SCHPO	ARS-binding protein 1	17112379	The CENP-B homolog, Abp1, interacts with the initiation protein Cdc23 (MCM10) and is required for efficient DNA replication in fission yeast.

P18910	ANPRA_RAT	Atrial natriuretic peptide receptor 1	2563900	A membrane form of guanylate cyclase is an atrial natriuretic peptide receptor.

Q8LBZ7	DHSB1_ARATH	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit 1, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q6ZPF3	TIAM2_MOUSE	T-lymphoma invasion and metastasis-inducing protein 2	10364228	Identification of the stef gene that encodes a novel guanine nucleotide exchange factor specific for Rac1.

O60477	DBC1_HUMAN	Deleted in bladder cancer protein 1	14712213	DBCCR1 mediates death in cultured bladder tumor cells.

Q12905	ILF2_HUMAN	Interleukin enhancer-binding factor 2	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

Q9NH52	MES4_CAEEL	Histone-lysine N-methyltransferase mes-4	12077420	Regulation of the different chromatin states of autosomes and X chromosomes in the germ line of C. elegans.

Q9UKN1	MUC12_HUMAN	Mucin-12	10463611	Two novel mucin genes down-regulated in colorectal cancer identified by differential display.

P0A1Z9	CSGC_SALEN	Curli assembly protein csgC	17379722	AgfC and AgfE facilitate extracellular thin aggregative fimbriae synthesis in Salmonella enteritidis.

P36101	YKC7_YEAST	Uncharacterized protein YKL027W	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q99613	EIF3C_HUMAN	Eukaryotic translation initiation factor 3 subunit C	17581632	Reconstitution reveals the functional core of mammalian eIF3.

P35221	CTNA1_HUMAN	Catenin alpha-1	8323564	Cloning of the human alpha-catenin cDNA and its aberrant mRNA in a human cancer cell line.

Q8VHC3	SELM_MOUSE	Selenoprotein M	11839807	Mammalian selenoprotein in which selenocysteine (Sec) incorporation is supported by a new form of Sec insertion sequence element.

Q8LPQ9	FPA_ARATH	Flowering time control protein FPA	20079695	The spen family protein FPA controls alternative cleavage and polyadenylation of RNA.

Q80W94	MOGT2_MOUSE	2-acylglycerol O-acyltransferase 2	14966132	A predominant role of acyl-CoA:monoacylglycerol acyltransferase-2 in dietary fat absorption implicated by tissue distribution, subcellular localization, and up-regulation by high fat diet.

P03951	FA11_HUMAN	Coagulation factor XI	9593722	Molecular cloning of platelet factor XI, an alternative splicing product of the plasma factor XI gene.

O89107	DNSL3_RAT	Deoxyribonuclease gamma	9665719	DNaseY: a rat DNaseI-like gene coding for a constitutively expressed chromatin-bound endonuclease.

O74910	RAF1_SCHPO	Rik1-associated factor 1	16024659	A Rik1-associated, cullin-dependent E3 ubiquitin ligase is essential for heterochromatin formation.

Q25519	PRP2_MANSE	Phenoloxidase subunit 2	16291091	Prophenoloxidase binds to the surface of hemocytes and is involved in hemocyte melanization in Manduca sexta.

P61829	ATP9_YEAST	ATP synthase subunit 9, mitochondrial	2894987	NH2-terminal sequence of the isolated yeast ATP synthase subunit 6 reveals post-translational cleavage.

P48728	GCST_HUMAN	Aminomethyltransferase, mitochondrial	8188235	Structure and chromosomal localization of the aminomethyltransferase gene (AMT).

Q9UBP5	HEY2_HUMAN	Hairy/enhancer-of-split related with YRPW motif protein 2	10415358	Hey genes: a novel subfamily of hairy- and enhancer of split related genes specifically expressed during mouse embryogenesis.

Q9WU34	SEPT3_RAT	Neuronal-specific septin-3	15107017	Phosphorylation of septin 3 on Ser-91 by cGMP-dependent protein kinase-I in nerve terminals.

P38316	ATG12_YEAST	Ubiquitin-like protein ATG12	9759731	A protein conjugation system essential for autophagy.

Q03761	TAF12_YEAST	Transcription initiation factor TFIID subunit 12	12446794	The novel SLIK histone acetyltransferase complex functions in the yeast retrograde response pathway.

P32874	HFA1_YEAST	Acetyl-CoA carboxylase, mitochondrial	14761959	HFA1 encoding an organelle-specific acetyl-CoA carboxylase controls mitochondrial fatty acid synthesis in Saccharomyces cerevisiae.

Q9VUQ5	AGO2_DROME	Protein argonaute-2	11498593	Argonaute2, a link between genetic and biochemical analyses of RNAi.

P33309	DOM34_YEAST	Protein DOM34	16554824	Endonucleolytic cleavage of eukaryotic mRNAs with stalls in translation elongation.

Q8IUH5	ZDH17_HUMAN	Palmitoyltransferase ZDHHC17	12761501	Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.

Q9FML2	HDA6_ARATH	Histone deacetylase 6	12445118	COI1 links jasmonate signalling and fertility to the SCF ubiquitin- ligase complex in Arabidopsis.

O88665	BRD7_MOUSE	Bromodomain-containing protein 7	10526152	Identification and molecular characterization of BP75, a novel bromodomain-containing protein.

P26358	DNMT1_HUMAN	DNA (cytosine-5)-methyltransferase 1	8940105	New 5' regions of the murine and human genes for DNA (cytosine-5)- methyltransferase.

P25870	CLH_DICDI	Clathrin heavy chain	1522112	Clathrin heavy chain is required for pinocytosis, the presence of large vacuoles, and development in Dictyostelium.

P22605	RARB_MOUSE	Retinoic acid receptor beta	1313565	RAR-beta 4, a retinoic acid receptor isoform is generated from RAR- beta 2 by alternative splicing and usage of a CUG initiator codon.

Q54TY7	SRFA_DICDI	Serum response factor homolog A	9729488	A serum response factor homolog is required for spore differentiation in Dictyostelium.

Q9Y4L5	RN115_HUMAN	E3 ubiquitin-protein ligase RNF115	16288031	A novel RING-type ubiquitin ligase breast cancer-associated gene 2 correlates with outcome in invasive breast cancer.

Q99P58	RB27B_MOUSE	Ras-related protein Rab-27B	16716193	Decreased basal mucus secretion by Slp2-a-deficient gastric surface mucous cells.

P40967	PME17_HUMAN	Melanocyte protein Pmel 17	11694580	Pmel17 initiates premelanosome morphogenesis within multivesicular bodies.

P62306	RUXF_HUMAN	Small nuclear ribonucleoprotein F	11574479	Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein.

P37023	ACVL1_HUMAN	Serine/threonine-protein kinase receptor R3	8242742	Identification of human activin and TGF beta type I receptors that form heteromeric kinase complexes with type II receptors.

Q8VE73	CUL7_MOUSE	Cullin-7	12904573	Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis.

Q9CAJ0	P2C16_ARATH	Protein phosphatase 2C 16	19033529	HAB1-SWI3B interaction reveals a link between abscisic acid signaling and putative SWI/SNF chromatin-remodeling complexes in Arabidopsis.

Q9W261	RTF1_DROME	RNA polymerase-associated protein Rtf1	16354696	Drosophila Paf1 modulates chromatin structure at actively transcribed genes.

O84947	SSEC_SALTY	Secreted effector protein sseC	9786193	Genes encoding putative effector proteins of the type III secretion system of Salmonella pathogenicity island 2 are required for bacterial virulence and proliferation in macrophages.

Q96CV9	OPTN_HUMAN	Optineurin	9488477	Interaction of an adenovirus E3 14.7-kilodalton protein with a novel tumor necrosis factor alpha-inducible cellular protein containing leucine zipper domains.

Q9UGB7	MIOX_HUMAN	Inositol oxygenase	10944187	Identification of a renal-specific oxido-reductase in newborn diabetic mice.

P46639	KNAT1_ARATH	Homeobox protein knotted-1-like 1	11917137	The homeobox gene BREVIPEDICELLUS is a key regulator of inflorescence architecture in Arabidopsis.

Q9Y2Z4	SYYM_HUMAN	Tyrosyl-tRNA synthetase, mitochondrial	10810093	Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics.

P40168	YNT5_YEAST	Uncharacterized protein YNL195C	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P10599	THIO_HUMAN	Thioredoxin	19690162	Salmonella type III secretion effector SlrP is an E3 ubiquitin ligase for mammalian thioredoxin.

P36078	HOT13_YEAST	Helper of Tim protein 13	15294910	The role of Hot13p and redox chemistry in the mitochondrial TIM22 import pathway.

P15539	C11B2_MOUSE	Cytochrome P450 11B2, mitochondrial	1686470	Different isozymes of mouse 11 beta-hydroxylase produce mineralocorticoids and glucocorticoids.

P32578	SIP1_YEAST	SNF1 protein kinase subunit beta-1	12393914	Purification and characterization of Snf1 kinase complexes containing a defined beta subunit composition.

P04637	P53_HUMAN	Cellular tumor antigen p53	15053879	Phosphorylation on Thr-55 by TAF1 mediates degradation of p53: a role for TAF1 in cell G1 progression.

Q94523	DHSA_DROME	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	18599508	Reactive oxygen species act remotely to cause synapse loss in a Drosophila model of developmental mitochondrial encephalopathy.

P09919	CSF3_HUMAN	Granulocyte colony-stimulating factor	2420009	Recombinant human granulocyte colony-stimulating factor: effects on normal and leukemic myeloid cells.

Q5ATQ3	PGLR_EMENI	Endopolygalacturonase AN8327	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

P21399	ACOC_HUMAN	Cytoplasmic aconitate hydratase	8041788	The bifunctional iron-responsive element binding protein/cytosolic aconitase: the role of active-site residues in ligand binding and regulation.

P00751	CFAB_HUMAN	Complement factor B	8225386	Human complement factor B: functional properties of a recombinant zymogen of the alternative activation pathway convertase.

O75436	VP26A_HUMAN	Vacuolar protein sorting-associated protein 26A	11102511	Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: assembly into multimeric complexes.

Q920V1	B3GL1_MOUSE	UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1	9417047	Genomic cloning and expression of three murine UDP-galactose: beta-N- acetylglucosamine beta1,3-galactosyltransferase genes.

O35493	CLK4_MOUSE	Dual specificity protein kinase CLK4	9307018	Characterization and comparison of four serine- and arginine-rich (SR) protein kinases.

O13792	SUB2_SCHPO	ATP-dependent RNA helicase uap56	15990877	Homolog of BRCA2-interacting Dss1p and Uap56p link Mlo3p and Rae1p for mRNA export in fission yeast.

P55290	CAD13_HUMAN	Cadherin-13	10737605	Expression of T-cadherin (CDH13, H-Cadherin) in human brain and its characteristics as a negative growth regulator of epidermal growth factor in neuroblastoma cells.

Q9P7Y8	MID2_SCHPO	Septin ring organizing protein mid2	12654901	Mid2p stabilizes septin rings during cytokinesis in fission yeast.

Q13416	ORC2_HUMAN	Origin recognition complex subunit 2	8808289	Mouse and human homologues of the yeast origin of replication recognition complex subunit ORC2 and chromosomal localization of the cognate human gene ORC2L.

P36016	LHS1_YEAST	Heat shock protein 70 homolog LHS1	14704430	Coordinated activation of Hsp70 chaperones.

P13607	ATNA_DROME	Sodium/potassium-transporting ATPase subunit alpha	12598616	Neural dysfunction and neurodegeneration in Drosophila Na+/K+ ATPase alpha subunit mutants.

Q00916	RU17_YEAST	U1 small nuclear ribonucleoprotein 70 kDa homolog	10072386	Identification of eight proteins that cross-link to pre-mRNA in the yeast commitment complex.

P60896	DSS1_HUMAN	26S proteasome complex subunit DSS1	15117943	Sem1p is a novel subunit of the 26S proteasome from Saccharomyces cerevisiae.

Q9XSM0	PTGDS_SHEEP	Prostaglandin-H2 D-isomerase	10026099	Glutathione-independent prostaglandin D2 synthase in ram and stallion epididymal fluids: origin and regulation.

O95389	WISP3_HUMAN	WNT1-inducible-signaling pathway protein 3	9843955	WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors.

P32381	ARP2_YEAST	Actin-related protein 2	11248049	Arp2/3 complex and actin dynamics are required for actin-based mitochondrial motility in yeast.

Q9P7Y0	SSR4_SCHPO	SWI/SNF and RSC complexes subunit ssr4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P10644	KAP0_HUMAN	cAMP-dependent protein kinase type I-alpha regulatory subunit	1889088	Subtractive hybridization cloning of a tissue-specific extinguisher: TSE1 encodes a regulatory subunit of protein kinase A.

Q09329	MLO2_SCHPO	Protein mlo2	8972853	Fission yeast genes which disrupt mitotic chromosome segregation when overexpressed.

Q9Z1Z9	PDLI7_RAT	PDZ and LIM domain protein 7	9832452	LMP-1, a LIM-domain protein, mediates BMP-6 effects on bone formation.

Q9V4P1	ANLN_DROME	Actin-binding protein anillin	9013326	Assembly of ring canals in the male germ line from structural components of the contractile ring.

Q99426	TBCB_HUMAN	Tubulin-folding cofactor B	8978778	Cloning, expression, and mapping of CKAPI, which encodes a putative cytoskeleton-associated protein containing a CAP-Gly domain.

P32591	SWI3_YEAST	SWI/SNF complex subunit SWI3	16204215	The RSC chromatin remodeling complex bears an essential fungal- specific protein module with broad functional roles.

Q9HCK8	CHD8_HUMAN	Chromodomain-helicase-DNA-binding protein 8	17938208	CHD8 associates with human Staf and contributes to efficient U6 RNA polymerase III transcription.

Q570C0	TIR1_ARATH	Protein TRANSPORT INHIBITOR RESPONSE 1	15917797	The F-box protein TIR1 is an auxin receptor.

Q8N307	MUC20_HUMAN	Mucin-20	15314156	MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met.

P13693	TCTP_HUMAN	Translationally-controlled tumor protein	16548883	Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection.

Q9NYW0	T2R10_HUMAN	Taste receptor type 2 member 10	10761934	A novel family of mammalian taste receptors.

P40849	MFM3_SCHPO	M-factor	8196631	Analysis of the structural genes encoding M-factor in the fission yeast Schizosaccharomyces pombe: identification of a third gene, mfm3.

O70551	SRPK1_MOUSE	Serine/threonine-protein kinase SRPK1	9446799	Novel SR-protein-specific kinase, SRPK2, disassembles nuclear speckles.

Q04172	SHE9_YEAST	Sensitive to high expression protein 9, mitochondrial	12591915	The inner membrane protein Mdm33 controls mitochondrial morphology in yeast.

Q9UU79	NSA2_SCHPO	Ribosome biogenesis protein nsa2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P41912	ERFD_YEAST	Ras modification protein ERF4	7532279	Mutations in the SHR5 gene of Saccharomyces cerevisiae suppress Ras function and block membrane attachment and palmitoylation of Ras proteins.

O08605	MKNK1_MOUSE	MAP kinase-interacting serine/threonine-protein kinase 1	9155017	Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2.

P50535	MSL1_DROME	Protein male-specific lethal-1	12653959	Tamo selectively modulates nuclear import in Drosophila.

Q39080	DAD1_ARATH	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1	9225471	An Arabidopsis thaliana cDNA complementing a hamster apoptosis suppressor mutant.

Q811T9	DISC1_MOUSE	Disrupted in schizophrenia 1 homolog	19303846	Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling.

Q08961	RKM1_YEAST	Ribosomal N-lysine methyltransferase 1	14562095	Global analysis of protein localization in budding yeast.

P33315	TKT2_YEAST	Transketolase 2	7916691	TKL2, a second transketolase gene of Saccharomyces cerevisiae. Cloning, sequence and deletion analysis of the gene.

P25368	RRP7_YEAST	Ribosomal RNA-processing protein 7	9271380	Functional analysis of Rrp7p, an essential yeast protein involved in pre-rRNA processing and ribosome assembly.

Q9H4P4	RNF41_HUMAN	E3 ubiquitin-protein ligase NRDP1	15314180	Stabilization of the E3 ubiquitin ligase Nrdp1 by the deubiquitinating enzyme USP8.

Q54TR1	CFAD_DICDI	Counting factor associated protein D	18611962	The secreted Dictyostelium protein CfaD is a chalone.

P32198	CPT1A_RAT	Carnitine O-palmitoyltransferase 1, liver isoform	9169604	Topology of carnitine palmitoyltransferase I in the mitochondrial outer membrane.

O60200	MDM35_YEAST	Mitochondrial distribution and morphology protein 35	14562095	Global analysis of protein localization in budding yeast.

O75352	MPU1_HUMAN	Mannose-P-dolichol utilization defect 1 protein	11733564	MPDU1 mutations underlie a novel human congenital disorder of glycosylation, designated type If.

P40261	NNMT_HUMAN	Nicotinamide N-methyltransferase	8182091	Human liver nicotinamide N-methyltransferase. cDNA cloning, expression, and biochemical characterization.

Q9SJU4	ALFC1_ARATH	Probable fructose-bisphosphate aldolase 1, chloroplastic	16414959	Tocopherol cyclase (VTE1) localization and vitamin E accumulation in chloroplast plastoglobule lipoprotein particles.

P27364	3BHS5_RAT	3 beta-hydroxysteroid dehydrogenase type 5	2249649	Structure and sexual dimorphic expression of a liver-specific rat 3 beta-hydroxysteroid dehydrogenase/isomerase.

Q13891	BT3L2_HUMAN	Transcription factor BTF3 homolog 2	1386332	Genomic structure of the putative BTF3 transcription factor.

P53044	UFD1_YEAST	Ubiquitin fusion degradation protein 1	11740563	The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol.

Q9U2Q9	GSK3_CAEEL	Glycogen synthase kinase-3	16930586	Multiple redundant Wnt signaling components function in two processes during C. elegans vulval development.

P51460	INSL3_HUMAN	Insulin-like 3	8020942	Structural organization of the porcine and human genes coding for a Leydig cell-specific insulin-like peptide (LEY I-L) and chromosomal localization of the human gene (INSL3).

O74808	CLR1_SCHPO	Cryptic loci regulator protein 1	1644273	The clr1 locus regulates the expression of the cryptic mating-type loci of fission yeast.

P19541	RDS2_YEAST	Regulator of drug sensitivity 2	11943786	New regulators of drug sensitivity in the family of yeast zinc cluster proteins.

Q9NS23	RASF1_HUMAN	Ras association domain-containing protein 1	11333291	Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression.

P50875	SPT20_YEAST	Transcription factor SPT20	8649430	ADA5/SPT20 links the ADA and SPT genes, which are involved in yeast transcription.

P46309	GSH1_ARATH	Glutamate--cysteine ligase, chloroplastic	17144898	Identification of PAD2 as a gamma-glutamylcysteine synthetase highlights the importance of glutathione in disease resistance of Arabidopsis.

Q96HE7	ERO1A_HUMAN	ERO1-like protein alpha	11707400	Manipulation of oxidative protein folding and PDI redox state in mammalian cells.

P07262	DHE4_YEAST	NADP-specific glutamate dehydrogenase 1	2932370	Nucleotide sequence of the GDH gene coding for the NADP-specific glutamate dehydrogenase of Saccharomyces cerevisiae.

Q9M066	C90C1_ARATH	3-epi-6-deoxocathasterone 23-monooxygenase	9694802	The ROTUNDIFOLIA3 gene of Arabidopsis thaliana encodes a new member of the cytochrome P-450 family that is required for the regulated polar elongation of leaf cells.

P53784	SOX3_MOUSE	Transcription factor SOX-3	8625802	A comparison of the properties of Sox-3 with Sry and two related genes, Sox-1 and Sox-2.

Q02792	XRN2_YEAST	5'-3' exoribonuclease 2	8417335	An essential yeast gene with homology to the exonuclease-encoding XRN1/KEM1 gene also encodes a protein with exoribonuclease activity.

Q8CGT6	PIWL4_MOUSE	Piwi-like protein 4	18922463	A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice.

Q9EPC6	PROF2_RAT	Profilin-2	11027290	Profilin II is alternatively spliced, resulting in profilin isoforms that are differentially expressed and have distinct biochemical properties.

P53091	MCM6_YEAST	DNA replication licensing factor MCM6	9154825	A lesion in the DNA replication initiation factor Mcm10 induces pausing of elongation forks through chromosomal replication origins in Saccharomyces cerevisiae.

P39016	MPT5_YEAST	Suppressor protein MPT5	11157761	Post-transcriptional regulation through the HO 3'-UTR by Mpt5, a yeast homolog of Pumilio and FBF.

P63245	GBLP_RAT	Guanine nucleotide-binding protein subunit beta-2-like 1	8302854	Cloning of an intracellular receptor for protein kinase C: a homolog of the beta subunit of G proteins.

Q38997	KIN10_ARATH	SNF1-related protein kinase catalytic subunit alpha KIN10	11522840	Detection of in vivo protein interactions between Snf1-related kinase subunits with intron-tagged epitope-labelling in plants cells.

Q9SRT7	COBL1_ARATH	COBRA-like protein 1	12376623	The COBRA family of putative GPI-anchored proteins in Arabidopsis. A new fellowship in expansion.

O14609	XKRY_HUMAN	Testis-specific XK-related protein, Y-linked	9381176	Functional coherence of the human Y chromosome.

P83731	RL24_HUMAN	60S ribosomal protein L24	9582194	A map of 75 human ribosomal protein genes.

P61965	WDR5_MOUSE	WD repeat-containing protein 5	11551928	Cloning and characterization of a novel WD-40 repeat protein that dramatically accelerates osteoblastic differentiation.

P40650	SX11B_XENLA	Transcription factor Sox-11-B	9332350	XLS13A and XLS13B: SRY-related genes of Xenopus laevis.

P23526	SAHH_HUMAN	Adenosylhomocysteinase	2596825	Sequence of full length cDNA for human S-adenosylhomocysteine hydrolase.

O59805	YJV7_SCHPO	Putative amidase C550.07	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P0AE08	AHPC_ECOLI	Alkyl hydroperoxide reductase subunit C	7499381	Thioredoxin-linked 'thiol peroxidase' from periplasmic space of Escherichia coli.

Q9JL26	FMNL_MOUSE	Formin-like protein 1	10958683	FRL, a novel formin-related protein, binds to Rac and regulates cell motility and survival of macrophages.

P19021	AMD_HUMAN	Peptidyl-glycine alpha-amidating monooxygenase	7999037	Isolation and functional expression of human pancreatic peptidylglycine alpha-amidating monooxygenase.

Q99933	BAG1_HUMAN	BAG family molecular chaperone regulator 1	9679980	Expression and location of Hsp70/Hsc-binding anti-apoptotic protein BAG-1 and its variants in normal tissues and tumor cell lines.

Q91WA1	TIPIN_MOUSE	TIMELESS-interacting protein	17141802	Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factors.

P32561	RPD3_YEAST	Histone deacetylase RPD3	15141165	The unfolded protein response represses differentiation through the RPD3-SIN3 histone deacetylase.

P17707	DCAM_HUMAN	S-adenosylmethionine decarboxylase proenzyme	2460457	Structure and regulation of mammalian S-adenosylmethionine decarboxylase.

Q9WTJ6	MTL5_MOUSE	Tesmin	12606435	Native tesmin is a 60-kilodalton protein that undergoes dynamic changes in its localization during spermatogenesis in mice.

P53261	PESC_YEAST	Pescadillo homolog	16287855	Ytm1, Nop7, and Erb1 form a complex necessary for maturation of yeast 66S preribosomes.

Q38832	IAA14_ARATH	Auxin-responsive protein IAA14	11862947	Lateral root formation is blocked by a gain-of-function mutation in the SOLITARY-ROOT/IAA14 gene of Arabidopsis.

Q9NUX5	POTE1_HUMAN	Protection of telomeres protein 1	17237768	The POT1-TPP1 telomere complex is a telomerase processivity factor.

P39015	STM1_YEAST	Suppressor protein STM1	15044472	Stm1p, a G4 quadruplex and purine motif triplex nucleic acid-binding protein, interacts with ribosomes and subtelomeric Y' DNA in Saccharomyces cerevisiae.

Q15583	TGIF1_HUMAN	Homeobox protein TGIF1	10764806	Three-amino acid extension loop homeodomain proteins Meis2 and TGIF differentially regulate transcription.

P41902	CRS5_YEAST	Metallothionein-like protein CRS5	7929222	CRS5 encodes a metallothionein-like protein in Saccharomyces cerevisiae.

Q19319	CADH4_CAEEL	Cadherin-4	17213328	Axon guidance genes identified in a large-scale RNAi screen using the RNAi-hypersensitive Caenorhabditis elegans strain nre-1(hd20) lin- 15b(hd126).

P45724	PAL2_ARATH	Phenylalanine ammonia-lyase 2	7888622	The phenylalanine ammonia-lyase gene family in Arabidopsis thaliana.

Q99373	PET20_YEAST	Protein PET20, mitochondrial	16491469	Phenotypes of yeast mutants lacking the mitochondrial protein Pet20p.

P51787	KCNQ1_HUMAN	Potassium voltage-gated channel subfamily KQT member 1	8528244	Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias.

Q9NGX9	CP302_DROME	Cytochrome P450 302a1, mitochondrial	10976044	The Drosophila disembodied gene controls late embryonic morphogenesis and codes for a cytochrome P450 enzyme that regulates embryonic ecdysone levels.

Q9R1Z7	PTPS_MOUSE	6-pyruvoyl tetrahydrobiopterin synthase	9894812	Structure, genomic localization and recombinant expression of the mouse 6-pyruvoyl-tetrahydropterin synthase gene.

Q09933	DIS1_SCHPO	Phosphoprotein p93	7628693	p93dis1, which is required for sister chromatid separation, is a novel microtubule and spindle pole body-associating protein phosphorylated at the Cdc2 target sites.

Q9UGI9	AAKG3_HUMAN	5'-AMP-activated protein kinase subunit gamma-3	10698692	Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding.

Q99966	CITE1_HUMAN	Cbp/p300-interacting transactivator 1	8901575	msg1, a novel melanocyte-specific gene, encodes a nuclear protein and is associated with pigmentation.

P48740	MASP1_HUMAN	Mannan-binding lectin serine protease 1	12538697	Natural substrates and inhibitors of mannan-binding lectin-associated serine protease-1 and -2: a study on recombinant catalytic fragments.

Q9H211	CDT1_HUMAN	DNA replication factor Cdt1	14672932	The regulated association of Cdt1 with minichromosome maintenance proteins and Cdc6 in mammalian cells.

Q07914	TIM14_YEAST	Mitochondrial import inner membrane translocase subunit TIM14	14638855	A J-protein is an essential subunit of the presequence translocase- associated protein import motor of mitochondria.

Q3L254	WNT7B_CHICK	Protein Wnt-7b	16258938	Expression patterns of Wnt genes during development of an anterior part of the chicken eye.

Q6WNK7	SUS1_YEAST	Protein SUS1	15311284	Yeast centrin Cdc31 is linked to the nuclear mRNA export machinery.

P51115	FXR1A_XENLA	Fragile X mental retardation syndrome-related protein 1 homolog A	16000371	The RNA-binding protein Fragile X-related 1 regulates somite formation in Xenopus laevis.

P17967	PDI_YEAST	Protein disulfide-isomerase	1761554	The Saccharomyces cerevisiae TRG1 gene is essential for growth and encodes a lumenal endoplasmic reticulum glycoprotein involved in the maturation of vacuolar carboxypeptidase.

P09104	ENOG_HUMAN	Gamma-enolase	2045099	Complete structure of the human gene encoding neuron-specific enolase.

Q08955	CSM4_YEAST	Chromosome segregation in meiosis protein 4	12514182	Bipartite signals mediate subcellular targeting of tail-anchored membrane proteins in Saccharomyces cerevisiae.

Q96P71	NECA3_HUMAN	N-terminal EF-hand calcium-binding protein 3	10833507	Regulation of X11L-dependent amyloid precursor protein metabolism by XB51, a novel X11L-binding protein.

Q9W1F4	THOC5_DROME	THO complex subunit 5	15133499	Genome-wide analysis of mRNAs regulated by the THO complex in Drosophila.

P0A9J8	PHEA_ECOLI	P-protein	9497350	Chorismate mutase-prephenate dehydratase from Escherichia coli. Study of catalytic and regulatory domains using genetically engineered proteins.

Q96RI0	PAR4_HUMAN	Proteinase-activated receptor 4	9618465	Cloning and characterization of human protease-activated receptor 4.

P46643	AAT1_ARATH	Aspartate aminotransferase, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

O74389	MU176_SCHPO	Meiotically up-regulated gene 176 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9P6I8	YHG1_SCHPO	Zinc-type alcohol dehydrogenase-like protein C1198.01	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q6P253	DMKN_MOUSE	Dermokine	15256262	Identification of a conserved cluster of skin-specific genes encoding secreted proteins.

Q5FWY5	AIP_RAT	AH receptor-interacting protein	12810716	Attenuation of the activity of the cAMP-specific phosphodiesterase PDE4A5 by interaction with the immunophilin XAP2.

P0CC12	KAX85_ODODO	Potassium channel toxin alpha-KTx 8.5	17070524	The first potassium channel toxin from the venom of the Iranian scorpion Odonthobuthus doriae.

Q3YBR2	TBRG1_HUMAN	Transforming growth factor beta regulator 1	17110379	A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability.

Q8IZ57	NRSN1_HUMAN	Neurensin-1	12463420	Cloning, expression and characterization of a novel human VMP gene.

P40344	ATG3_YEAST	Autophagy-related protein 3	11149920	Membrane recruitment of Aut7p in the autophagy and cytoplasm to vacuole targeting pathways requires Aut1p, Aut2p, and the autophagy conjugation complex.

Q1PFR7	LEC2_ARATH	B3 domain-containing transcription factor LEC2	16492731	Genes directly regulated by LEAFY COTYLEDON2 provide insight into the control of embryo maturation and somatic embryogenesis.

Q8K448	ABCA5_MOUSE	ATP-binding cassette sub-family A member 5	15870284	ABCA5 resides in lysosomes, and ABCA5 knockout mice develop lysosomal disease-like symptoms.

Q920G2	NHRF2_RAT	Na(+)/H(+) exchange regulatory cofactor NHE-RF2	11124833	Ezrin-radixin-moesin-binding phosphoprotein 50 is expressed at the apical membrane of rat liver epithelia.

P42859	HD_MOUSE	Huntingtin	7647777	Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form.

Q96EP0	RNF31_HUMAN	RING finger protein 31	17006537	A ubiquitin ligase complex assembles linear polyubiquitin chains.

O15304	SIVA_HUMAN	Apoptosis regulatory protein Siva	16683188	The zinc containing pro-apoptotic protein siva interacts with the peroxisomal membrane protein pmp22.

Q55EK9	PDXK_DICDI	Pyridoxal kinase	10930737	Pyridoxal kinase knockout of Dictyostelium complemented by the human homologue.

P33442	RS3A1_YEAST	40S ribosomal protein S1-A	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q9JJ06	C1GLT_MOUSE	Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1	14745002	Defective angiogenesis and fatal embryonic hemorrhage in mice lacking core 1-derived O-glycans.

Q94KL5	BLH4_ARATH	BEL1-like homeodomain protein 4	17873098	The Arabidopsis BEL1-LIKE HOMEODOMAIN proteins SAW1 and SAW2 act redundantly to regulate KNOX expression spatially in leaf margins.

Q9BY77	PDIP3_HUMAN	Polymerase delta-interacting protein 3	18423201	SKAR links pre-mRNA splicing to mTOR/S6K1-mediated enhanced translation efficiency of spliced mRNAs.

Q9SV96	PP358_ARATH	Pentatricopeptide repeat-containing protein At4g39620, chloroplastic	15647901	Arabidopsis emb175 and other ppr knockout mutants reveal essential roles for pentatricopeptide repeat (PPR) proteins in plant embryogenesis.

Q8W2F3	PIF4_ARATH	Transcription factor PIF4	12006496	PIF4, a phytochrome-interacting bHLH factor, functions as a negative regulator of phytochrome B signaling in Arabidopsis.

Q62141	SIN3B_MOUSE	Paired amphipathic helix protein Sin3b	9702189	SAP30, a component of the mSin3 corepressor complex involved in N- CoR-mediated repression by specific transcription factors.

P32908	SMC1_YEAST	Structural maintenance of chromosomes protein 1	8276886	SMC1: an essential yeast gene encoding a putative head-rod-tail protein is required for nuclear division and defines a new ubiquitous protein family.

Q9UUI6	RTF_SCHPO	Replication termination factor 1	18723894	Rtf1-mediated eukaryotic site-specific replication termination.

Q61847	MEP1B_MOUSE	Meprin A subunit beta	8407940	Cloning, expression, and chromosomal localization of the mouse meprin beta subunit.

Q86KR9	P4HA_DICDI	Prolyl 4-hydroxylase subunit alpha	11358877	Analysis of Skp1 glycosylation and nuclear enrichment in Dictyostelium.

Q08236	AVO1_YEAST	Target of rapamycin complex 2 subunit AVO1	12408816	Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control.

Q86Y07	VRK2_HUMAN	Serine/threonine-protein kinase VRK2	9344656	Identification of two novel human putative serine/threonine kinases, VRK1 and VRK2, with structural similarity to Vaccinia virus B1R kinase.

Q99708	COM1_HUMAN	DNA endonuclease RBBP8	10764811	Nuclear localization and cell cycle-specific expression of CtIP, a protein that associates with the BRCA1 tumor suppressor.

Q9FJ82	DAPB3_ARATH	Putative dihydrodipicolinate reductase 3, chloroplastic	15652176	Biosynthesis of lysine in plants: evidence for a variant of the known bacterial pathways.

P11442	CLH_RAT	Clathrin heavy chain 1	3480512	Clathrin heavy chain: molecular cloning and complete primary structure.

P40502	AIM19_YEAST	Altered inheritance of mitochondria protein 19, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

Q810C0	SLIK2_MOUSE	SLIT and NTRK-like protein 2	14550773	Identification and characterization of Slitrk, a novel neuronal transmembrane protein family controlling neurite outgrowth.

Q62696	DLG1_RAT	Disks large homolog 1	16495444	A novel family of adhesion-like molecules that interacts with the NMDA receptor.

O65493	XCP1_ARATH	Xylem cysteine proteinase 1	11788755	The Arabidopsis xylem peptidase XCP1 is a tracheary element vacuolar protein that may be a papain ortholog.

Q9LH89	Y3885_ARATH	Uncharacterized protein At3g28850	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P35609	ACTN2_HUMAN	Alpha-actinin-2	11842093	Calsarcin-3, a novel skeletal muscle-specific member of the calsarcin family, interacts with multiple Z-disc proteins.

O42866	FABG_SCHPO	3-oxoacyl-[acyl-carrier-protein] reductase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q96P48	ARAP1_HUMAN	Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1	18165900	Arf and Rho GAP adapter protein ARAP1 participates in the mobilization of TRAIL-R1/DR4 to the plasma membrane.

Q07553	GCY3E_DROME	Guanylate cyclase 32E	8104831	A membrane guanylate cyclase Drosophila homolog gene exhibits maternal and zygotic expression.

Q9Z2P8	VAMP5_MOUSE	Vesicle-associated membrane protein 5	9725904	A novel synaptobrevin/VAMP homologous protein (VAMP5) is increased during in vitro myogenesis and present in the plasma membrane.

Q9NV92	NFIP2_HUMAN	NEDD4 family-interacting protein 2	12761501	Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.

P40186	PCL7_YEAST	PHO85 cyclin-7	11602261	The yeast cyclins Pcl6p and Pcl7p are involved in the control of glycogen storage by the cyclin-dependent protein kinase Pho85p.

P19488	UDB37_RAT	UDP-glucuronosyltransferase 2B37	1692835	The cDNA sequence and expression of a variant 17 beta-hydroxysteroid UDP-glucuronosyltransferase.

Q9Y7T2	YCJ6_SCHPO	Uncharacterized WD repeat-containing protein C63.06	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q55FT9	ABIA_DICDI	Abl interactor homolog	17314411	The N-terminus of Dictyostelium Scar interacts with Abi and HSPC300 and is essential for proper regulation and function.

Q86QI5	DEF1_DERVA	Defensin	11439245	Identification of a defensin from the hemolymph of the American dog tick, Dermacentor variabilis.

Q0WQF7	OPD21_ARATH	Dihydrolipoyllysine-residue acetyltransferase component 1 of pyruvate dehydrogenase complex, mitochondrial	14764908	Lipoic acid-dependent oxidative catabolism of alpha-keto acids in mitochondria provides evidence for branched-chain amino acid catabolism in Arabidopsis.

P83402	AL7A1_ACASC	Alpha-aminoadipic semialdehyde dehydrogenase	11959129	First purification of the antiquitin protein and demonstration of its enzymatic activity.

Q99MB1	TLR3_MOUSE	Toll-like receptor 3	11607032	Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3.

Q06547	GABP1_HUMAN	GA-binding protein subunit beta-1	10675337	The novel coactivator C1 (HCF) coordinates multiprotein enhancer formation and mediates transcription activation by GABP.

Q8BN78	KAISO_MOUSE	Transcriptional regulator Kaiso	10207085	The catenin p120(ctn) interacts with Kaiso, a novel BTB/POZ domain zinc finger transcription factor.

P98164	LRP2_HUMAN	Low-density lipoprotein receptor-related protein 2	7768901	Identification of glycoprotein 330 as an endocytic receptor for apolipoprotein J/clusterin.

Q8WU20	FRS2_HUMAN	Fibroblast growth factor receptor substrate 2	9660748	Novel recognition motif on fibroblast growth factor receptor mediates direct association and activation of SNT adapter proteins.

Q9QW07	PLCB4_RAT	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4	7688223	Cloning of cDNA encoding rat phospholipase C-beta 4, a new member of the phospholipase C.

Q9BY64	UDB28_HUMAN	UDP-glucuronosyltransferase 2B28	11300766	Isolation and characterization of the UGT2B28 cDNA encoding a novel human steroid conjugating UDP-glucuronosyltransferase.

Q13794	APR_HUMAN	Phorbol-12-myristate-13-acetate-induced protein 1	15694340	Differential targeting of prosurvival Bcl-2 proteins by their BH3- only ligands allows complementary apoptotic function.

O94530	SUA5_SCHPO	Protein sua5	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O81770	MGDG1_ARATH	Monogalactosyldiacylglycerol synthase 1, chloroplastic	10869420	Galactolipid deficiency and abnormal chloroplast development in the Arabidopsis MGD synthase 1 mutant.

P53632	PAP2_YEAST	Poly(A) RNA polymerase protein 2	17179095	Contribution of Trf4/5 and the nuclear exosome to genome stability through regulation of histone mRNA levels in Saccharomyces cerevisiae.

P07258	CARA_YEAST	Carbamoyl-phosphate synthase arginine-specific small chain	6086650	Sequence of the small subunit of yeast carbamyl phosphate synthetase and identification of its catalytic domain.

Q14669	TRIPC_HUMAN	Probable E3 ubiquitin-protein ligase TRIP12	7776974	Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor.

Q8CHI5	PER1_RAT	Period circadian protein homolog 1	15094047	Indication of circadian oscillations in the rat pancreas.

Q9US14	YK64_SCHPO	Uncharacterized inositol polyphosphate kinase C607.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q92878	RAD50_HUMAN	DNA repair protein RAD50	10888888	Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres.

O43464	HTRA2_HUMAN	Serine protease HTRA2, mitochondrial	10873535	Expression, purification, and functional analysis of the human serine protease HtrA2.

P49674	KC1E_HUMAN	Casein kinase I isoform epsilon	16618118	Dysbindin structural homologue CK1BP is an isoform-selective binding partner of human casein kinase-1.

P38749	YAP3_YEAST	AP-1-like transcription factor YAP3	9372930	Yap, a novel family of eight bZIP proteins in Saccharomyces cerevisiae with distinct biological functions.

Q9Y2U8	MAN1_HUMAN	Inner nuclear membrane protein Man1	10671519	MAN1, an inner nuclear membrane protein that shares the LEM domain with lamina-associated polypeptide 2 and emerin.

Q02297	NRG1_HUMAN	Pro-neuregulin-1, membrane-bound isoform	1348215	Isolation of the neu/HER-2 stimulatory ligand: a 44 kd glycoprotein that induces differentiation of mammary tumor cells.

Q9P2X7	DEC1_HUMAN	Deleted in esophageal cancer 1	10612805	Isolation and mutational analysis of a novel human cDNA, DEC1 (deleted in esophageal cancer 1), derived from the tumor-suppressor locus on chromosome 9q32.

Q99297	ODC2_YEAST	Mitochondrial 2-oxodicarboxylate carrier 2	11013234	Identification in Saccharomyces cerevisiae of two isoforms of a novel mitochondrial transporter for 2-oxoadipate and 2-oxoglutarate.

P29509	TRXB1_YEAST	Thioredoxin reductase 1	7961686	Thioredoxin-dependent peroxide reductase from yeast.

P29468	PAP_YEAST	Poly(A) polymerase	12819204	Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-ends.

Q12947	FOXF2_HUMAN	Forkhead box protein F2	9722567	The human forkhead protein FREAC-2 contains two functionally redundant activation domains and interacts with TBP and TFIIB.

P53174	PRM8_YEAST	Pheromone-regulated membrane protein 8	12925749	Suppression of coatomer mutants by a new protein family with COPI and COPII binding motifs in Saccharomyces cerevisiae.

Q94F30	ESD4_ARATH	Ubiquitin-like-specific protease ESD4	14507998	A nuclear protease required for flowering-time regulation in Arabidopsis reduces the abundance of SMALL UBIQUITIN-RELATED MODIFIER conjugates.

P35582	FOXA1_MOUSE	Hepatocyte nuclear factor 3-alpha	17596284	Foxa1 and Foxa2 regulate multiple phases of midbrain dopaminergic neuron development in a dosage-dependent manner.

P21575	DYN1_RAT	Dynamin-1	9238017	The SH3p4/Sh3p8/SH3p13 protein family: binding partners for synaptojanin and dynamin via a Grb2-like Src homology 3 domain.

P80316	TCPE_MOUSE	T-complex protein 1 subunit epsilon	7953530	Identification of six Tcp-1-related genes encoding divergent subunits of the TCP-1-containing chaperonin.

Q9QZS3	NUMB_MOUSE	Protein numb homolog	17174898	Postnatal deletion of Numb/Numblike reveals repair and remodeling capacity in the subventricular neurogenic niche.

Q13950	RUNX2_HUMAN	Runt-related transcription factor 2	9182765	Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia.

P40100	PUG1_YEAST	Protoporphyrin uptake protein 1	18326586	Role of PUG1 in inducible porphyrin and heme transport in Saccharomyces cerevisiae.

O14654	IRS4_HUMAN	Insulin receptor substrate 4	9553137	Characterization of insulin receptor substrate 4 in human embryonic kidney 293 cells.

P28750	EXU_DROME	Maternal protein exuperantia	1756733	The temporal and spatial distribution pattern of maternal exuperantia protein: evidence for a role in establishment but not maintenance of bicoid mRNA localization.

Q9V4A7	PLXB_DROME	Plexin-B	11604137	Plexin B mediates axon guidance in Drosophila by simultaneously inhibiting active Rac and enhancing RhoA signaling.

P23441	NKX21_RAT	Homeobox protein Nkx-2.1	1976511	Thyroid nuclear factor 1 (TTF-1) contains a homeodomain and displays a novel DNA binding specificity.

O06203	ACYLT_MYCTU	Phosphatidylinositol mannoside acyltransferase	12851411	Identification of the required acyltransferase step in the biosynthesis of the phosphatidylinositol mannosides of mycobacterium species.

Q12200	NPC1_YEAST	Niemann-Pick type C-related protein 1	14970192	Mutagenesis of the putative sterol-sensing domain of yeast Niemann Pick C-related protein reveals a primordial role in subcellular sphingolipid distribution.

Q13769	THOC5_HUMAN	THO complex subunit 5 homolog	19165146	Adaptor Aly and co-adaptor Thoc5 function in the Tap-p15-mediated nuclear export of HSP70 mRNA.

P32629	ANP1_YEAST	Mannan polymerase II complex ANP1 subunit	9430634	Multi-protein complexes in the cis Golgi of Saccharomyces cerevisiae with alpha-1,6-mannosyltransferase activity.

O81242	RHL1_ARATH	DNA-binding protein RHL1	16339310	RHL1 is an essential component of the plant DNA topoisomerase VI complex and is required for ploidy-dependent cell growth.

Q10326	MUG8_SCHPO	Meiotically up-regulated gene 8 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P10114	RAP2A_HUMAN	Ras-related protein Rap-2a	3045729	Human cDNAs rap1 and rap2 homologous to the Drosophila gene Dras3 encode proteins closely related to ras in the 'effector' region.

Q8BIK6	TMPS7_MOUSE	Transmembrane protease serine 7	15853774	Matriptase-3 is a novel phylogenetically preserved membrane-anchored serine protease with broad serpin reactivity.

Q13485	SMAD4_HUMAN	Mothers against decapentaplegic homolog 4	9389648	Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes.

P39956	RPH1_YEAST	DNA damage-responsive transcriptional repressor RPH1	10523651	RPH1 and GIS1 are damage-responsive repressors of PHR1.

P35222	CTNB1_HUMAN	Catenin beta-1	20164195	The phospholipid-binding protein SESTD1 is a novel regulator of the transient receptor potential channels TRPC4 and TRPC5.

P50946	OCA1_YEAST	Putative tyrosine-protein phosphatase OCA1	14562095	Global analysis of protein localization in budding yeast.

P38968	SEC31_YEAST	Protein transport protein SEC31	9325247	COPII subunit interactions in the assembly of the vesicle coat.

O00410	IPO5_HUMAN	Importin-5	9114010	Cloning and characterization of human karyopherin beta3.

P40014	SPC25_YEAST	Kinetochore protein SPC25	11266451	The Ndc80p complex from Saccharomyces cerevisiae contains conserved centromere components and has a function in chromosome segregation.

Q6BDR8	NSE4_SCHPO	Non-structural maintenance of chromosome element 4	15601840	Composition and architecture of the Schizosaccharomyces pombe Rad18 (Smc5-6) complex.

Q9Z0H3	SNF5_MOUSE	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1	16787967	Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway?

Q9U1Y5	CHK2_CAEEL	Serine/threonine-protein kinase chk-2	11086161	Caenorhabditis elegans Chk2-like gene is essential for meiosis but dispensable for DNA repair.

Q08179	MDM38_YEAST	Mitochondrial distribution and morphology protein 38	15138253	The LETM1/YOL027 gene family encodes a factor of the mitochondrial K+ homeostasis with a potential role in the Wolf-Hirschhorn syndrome.

Q5FWP9	CE57R_XENLA	Cep57-related protein	17803911	Xenopus Cep57 is a novel kinetochore component involved in microtubule attachment.

O94344	YHMB_SCHPO	Uncharacterized mitochondrial carrier C1271.11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9M5P3	CCDA_ARATH	Cytochrome c-type biogenesis ccda-like chloroplastic protein	20214498	CcdA is a thylakoid membrane protein required for the transfer of reducing equivalents from stroma to thylakoid lumen in the higher plant chloroplast.

Q9H6Q3	SLAP2_HUMAN	Src-like-adapter 2	11696592	Functional cloning of Src-like adapter protein-2 (SLAP-2), a novel inhibitor of antigen receptor signaling.

P09208	INSR_DROME	Insulin-like receptor	11250149	An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control.

Q03441	RMD1_YEAST	Sporulation protein RMD1	14562095	Global analysis of protein localization in budding yeast.

O43014	MPI_SCHPO	Mannose-6-phosphate isomerase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9WTV7	RNF12_MOUSE	E3 ubiquitin-protein ligase RLIM	11882901	Ubiquitination-dependent cofactor exchange on LIM homeodomain transcription factors.

Q9SYK4	IP5PD_ARATH	Type I inositol-1,4,5-trisphosphate 5-phosphatase 13	15574849	Molecular and biochemical characterization of three WD-repeat-domain- containing inositol polyphosphate 5-phosphatases in Arabidopsis thaliana.

Q01574	ACS1_YEAST	Acetyl-coenzyme A synthetase 1	8910545	The two acetyl-coenzyme A synthetases of Saccharomyces cerevisiae differ with respect to kinetic properties and transcriptional regulation.

Q24372	LACH_DROME	Lachesin	14681183	Lachesin is a component of a septate junction-based mechanism that controls tube size and epithelial integrity in the Drosophila tracheal system.

Q12063	UPPS_YEAST	Probable undecaprenyl pyrophosphate synthase	11086160	A novel strategy for constructing N-terminal chromosomal fusions to green fluorescent protein in the yeast Saccharomyces cerevisiae.

Q7LKZ7	BPH1_SCHPO	Beige protein homolog 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12159	YRA1_YEAST	RNA annealing protein YRA1	11979277	TREX is a conserved complex coupling transcription with messenger RNA export.

O95633	FSTL3_HUMAN	Follistatin-related protein 3	12697670	Differential binding and neutralization of activins A and B by follistatin and follistatin like-3 (FSTL-3/FSRP/FLRG).

P36038	CBT1_YEAST	Cytochrome b termination protein 1	16118200	CBT1 interacts genetically with CBP1 and the mitochondrially encoded cytochrome b gene and is required to stabilize the mature cytochrome b mRNA of Saccharomyces cerevisiae.

Q2LAE1	ASHH2_ARATH	Histone-lysine N-methyltransferase ASHH2	16258034	Establishment of the vernalization-responsive, winter-annual habit in Arabidopsis requires a putative histone H3 methyl transferase.

Q09825	SAD1_SCHPO	Spindle pole body-associated protein sad1	16615890	Meiotic proteins bqt1 and bqt2 tether telomeres to form the bouquet arrangement of chromosomes.

Q9USG9	TYDP1_SCHPO	Probable tyrosyl-DNA phosphodiesterase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9EQY0	ERN1_MOUSE	Serine/threonine-protein kinase/endoribonuclease IRE1	11146108	Characterization of mouse Ire1alpha: cloning, mRNA localization in the brain and functional analysis in a neural cell line.

Q15762	CD226_HUMAN	CD226 antigen	8673704	DNAM-1, a novel adhesion molecule involved in the cytolytic function of T lymphocytes.

Q01831	XPC_HUMAN	DNA repair protein complementing XP-C cells	1522891	Expression cloning of a human DNA repair gene involved in Xeroderma pigmentosum group C.

Q9V5N8	STAN_DROME	Protocadherin-like wing polarity protein stan	10490098	Flamingo, a seven-pass transmembrane cadherin, regulates planar cell polarity under the control of frizzled.

Q9M2S6	SDIR1_ARATH	E3 ubiquitin-protein ligase SDIR1	17573536	SDIR1 is a RING finger E3 ligase that positively regulates stress- responsive abscisic acid signaling in Arabidopsis.

P13773	CAR1_DICDI	Cyclic AMP receptor 1	15574880	Constitutively active G protein-coupled receptor mutants block dictyostelium development.

P70658	CXCR4_MOUSE	C-X-C chemokine receptor type 4	9634237	The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract.

P06737	PYGL_HUMAN	Glycogen phosphorylase, liver form	10949035	Activation of human liver glycogen phosphorylase by alteration of the secondary structure and packing of the catalytic core.

Q04660	ERB1_YEAST	Ribosome biogenesis protein ERB1	18448671	Interactions among Ytm1, Erb1, and Nop7 required for assembly of the Nop7-subcomplex in yeast preribosomes.

O14686	MLL2_HUMAN	Histone-lysine N-methyltransferase MLL2	16603732	Identification of the MLL2 complex as a coactivator for estrogen receptor alpha.

Q54GE3	VPS45_DICDI	Vacuolar protein sorting-associated protein 45	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q969M7	UBE2F_HUMAN	NEDD8-conjugating enzyme UBE2F	19250909	E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification.

Q9EPS3	GLCE_MOUSE	D-glucuronyl C5-epimerase	11279150	Cloning, Golgi localization, and enzyme activity of the full-length heparin/heparan sulfate-glucuronic acid C5-epimerase.

P61964	WDR5_HUMAN	WD repeat-containing protein 5	17355966	Identification and characterization of the human Set1B histone H3- Lys4 methyltransferase complex.

O95497	VNN1_HUMAN	Pantetheinase	9790769	Two human genes related to murine vanin-1 are located on the long arm of human chromosome 6.

Q6K1E7	GGNB1_MOUSE	Gametogenetin-binding protein 1	19208545	A novel potential role for gametogenetin-binding protein 1 (GGNBP1) in mitochondrial morphogenesis during spermatogenesis in mice.

O95905	SGT1_HUMAN	Protein SGT1	9928932	A human gene, hSGT1, can substitute for GCR2, which encodes a general regulatory factor of glycolytic gene expression in Saccharomyces cerevisiae.

Q63014	AKAP8_RAT	A-kinase anchor protein 8	8125992	Cloning and characterization of AKAP 95, a nuclear protein that associates with the regulatory subunit of type II cAMP-dependent protein kinase.

Q12235	YL055_YEAST	Uncharacterized transporter YLL055W	14562095	Global analysis of protein localization in budding yeast.

P53333	CWC22_YEAST	Pre-mRNA-splicing factor CWC22	11884590	Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

Q5RJA1	RFX6_DANRE	DNA-binding protein RFX6	20040487	Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development.

Q5AU62	NMRA_EMENI	Nitrogen metabolite repression protein nmrA	12764138	The negative transcriptional regulator NmrA discriminates between oxidized and reduced dinucleotides.

O75674	TM1L1_HUMAN	TOM1-like protein 1	10329004	TOM1 genes map to human chromosome 22q13.1 and mouse chromosome 8C1 and encode proteins similar to the endosomal proteins HGS and STAM.

P47138	DPH4_YEAST	Diphthamide biosynthesis protein 4	15485916	Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2.

Q96CA5	BIRC7_HUMAN	Baculoviral IAP repeat-containing protein 7	11865055	IAP suppression of apoptosis involves distinct mechanisms: the TAK1/JNK1 signaling cascade and caspase inhibition.

Q93074	MED12_HUMAN	Mediator of RNA polymerase II transcription subunit 12	10235266	Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex.

P21691	SIR1_YEAST	Regulatory protein SIR1	12198162	Structure and function of the BAH-containing domain of Orc1p in epigenetic silencing.

Q93100	KPBB_HUMAN	Phosphorylase b kinase regulatory subunit beta	9402963	Phosphorylase-kinase-deficient liver glycogenosis with an unusual biochemical phenotype in blood cells associated with a missense mutation in the beta subunit gene (PHKB).

Q9LU86	PRXQ_ARATH	Peroxiredoxin Q, chloroplastic	16507087	Peroxiredoxin Q of Arabidopsis thaliana is attached to the thylakoids and functions in context of photosynthesis.

P34110	VPS35_YEAST	Vacuolar protein sorting-associated protein 35	9700157	A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeast.

P35583	FOXA2_MOUSE	Hepatocyte nuclear factor 3-beta	15668254	Compensatory roles of Foxa1 and Foxa2 during lung morphogenesis.

Q13370	PDE3B_HUMAN	cGMP-inhibited 3',5'-cyclic phosphodiesterase B	8884271	Characterization of the cDNA and gene encoding human PDE3B, the cGIP1 isoform of the human cyclic GMP-inhibited cyclic nucleotide phosphodiesterase family.

O65041	UBA3_ARATH	NEDD8-activating enzyme E1 catalytic subunit	9624055	The ubiquitin-related protein RUB1 and auxin response in Arabidopsis.

Q9JI92	SDCB1_RAT	Syntenin-1	11152476	The neural cell recognition molecule neurofascin interacts with syntenin-1 but not with syntenin-2, both of which reveal self- associating activity.

P36040	POC2_YEAST	Proteasome assembly chaperone 2	12711700	Differential requirements of novel A1PiZ degradation deficient (ADD) genes in ER-associated protein degradation.

P53845	YIF1_YEAST	Protein transport protein YIF1	12615067	The yeast model for Batten disease: a role for Btn2p in the trafficking of the Golgi-associated vesicular targeting protein, Yif1p.

P61364	OSTN_MOUSE	Osteocrin	14523025	Osteocrin, a novel bone-specific secreted protein that modulates the osteoblast phenotype.

Q9UK22	FBX2_HUMAN	F-box only protein 2	10531035	Identification of a family of human F-box proteins.

P62318	SMD3_HUMAN	Small nuclear ribonucleoprotein Sm D3	7527560	cDNA cloning of the Sm proteins D2 and D3 from human small nuclear ribonucleoproteins: evidence for a direct D1-D2 interaction.

P83187	BRB_BASAL	Beta-basrubin	11688973	Novel antifungal peptides from ceylon spinach seeds.

Q02981	YP109_YEAST	ABC1 family protein YPL109C, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

Q9R1Z0	VDAC3_RAT	Voltage-dependent anion-selective channel protein 3	10998068	Characterization of porin isoforms expressed in tumor cells.

Q9U1S7	PKD2_CAEEL	Polycystin-2	12411744	Towards understanding the polycystins.

Q9H1C4	UN93B_HUMAN	Protein unc-93 homolog B1	19006693	IRAK-4- and MyD88-dependent pathways are essential for the removal of developing autoreactive B cells in humans.

Q9ULZ3	ASC_HUMAN	Apoptosis-associated speck-like protein containing a CARD	12656673	The PAAD/PYRIN-only protein POP1/ASC2 is a modulator of ASC-mediated nuclear-factor-kappa B and pro-caspase-1 regulation.

P40469	MET18_YEAST	DNA repair/transcription protein MET18/MMS19	8943333	Dual requirement for the yeast MMS19 gene in DNA repair and RNA polymerase II transcription.

Q92598	HS105_HUMAN	Heat shock protein 105 kDa	9931472	Molecular cloning, expression and localization of human 105 kDa heat shock protein, hsp105.

Q39255	SKP1A_ARATH	SKP1-like protein 1A	11387208	SKP1-SnRK protein kinase interactions mediate proteasomal binding of a plant SCF ubiquitin ligase.

P97874	GAK_RAT	Cyclin-G-associated kinase	9013862	GAK: a cyclin G associated kinase contains a tensin/auxilin-like domain.

Q8T053	Y678_DROME	Uncharacterized zinc finger protein CG2678	9601978	Repetitive arrays containing a housekeeping gene promoter have altered polytene chromosome morphology in Drosophila.

P97789	XRN1_MOUSE	5'-3' exoribonuclease 1	9218715	Cloning and characterization of mouse Dhm2 cDNA, a functional homolog of budding yeast SEP1.

Q9CY02	AHSP_MOUSE	Alpha-hemoglobin-stabilizing protein	12066189	An abundant erythroid protein that stabilizes free alpha- haemoglobin.

Q60779	GAS8_MOUSE	Growth arrest-specific protein 8	11751847	Isolation and properties of Gas8, a growth arrest-specific gene regulated during male gametogenesis to produce a protein associated with the sperm motility apparatus.

P54315	LIPR1_HUMAN	Pancreatic lipase-related protein 1	1379598	Two novel human pancreatic lipase related proteins, hPLRP1 and hPLRP2. Differences in colipase dependence and in lipase activity.

O60488	ACSL4_HUMAN	Long-chain-fatty-acid--CoA ligase 4	9598324	Cloning, expression, and chromosomal localization of human long-chain fatty acid-CoA ligase 4 (FACL4).

Q9VNE2	EXBA_DROME	Protein extra bases	12593794	The staufen/pumilio pathway is involved in Drosophila long-term memory.

Q9ESD7	DYSF_MOUSE	Dysferlin	14506282	Dysferlin interacts with annexins A1 and A2 and mediates sarcolemmal wound-healing.

P11712	CP2C9_HUMAN	Cytochrome P450 2C9	2827463	Human cytochrome P-450 PB-1: a multigene family involved in mephenytoin and steroid oxidations that maps to chromosome 10.

Q9JKT3	TA2R4_MOUSE	Taste receptor type 2 member 4	10761934	A novel family of mammalian taste receptors.

Q9M5K2	DLDH2_ARATH	Dihydrolipoyl dehydrogenase 2, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P32329	YPS1_YEAST	Aspartic proteinase 3	16087741	Yapsins are a family of aspartyl proteases required for cell wall integrity in Saccharomyces cerevisiae.

Q9UTH9	DUS3_SCHPO	tRNA-dihydrouridine synthase 3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9SJT1	SAE2_ARATH	SUMO-activating enzyme subunit 2	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

Q9Z205	RFXK_MOUSE	DNA-binding protein RFXANK	10329666	The ankyrin repeat-containing adaptor protein tvl-1 is a novel substrate and regulator of raf-1.

Q12309	CLF1_YEAST	Pre-mRNA-splicing factor CLF1	12509417	The Clf1p splicing factor promotes spliceosome assembly through N- terminal tetratricopeptide repeat contacts.

Q38796	LUMI_ARATH	Homeobox protein LUMINIDEPENDENS	10363371	The Arabidopsis flowering-time gene LUMINIDEPENDENS is expressed primarily in regions of cell proliferation and encodes a nuclear protein that regulates LEAFY expression.

Q6PHQ8	NAA35_MOUSE	N-alpha-acetyltransferase 35, NatC auxiliary subunit	16484612	Embryonic growth-associated protein is one subunit of a novel N- terminal acetyltransferase complex essential for embryonic vascular development.

Q9NQP4	PFD4_HUMAN	Prefoldin subunit 4	9630229	Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin.

Q8IXJ6	SIRT2_HUMAN	NAD-dependent deacetylase sirtuin-2	10381378	Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity.

P53090	ARO8_YEAST	Aromatic amino acid aminotransferase 1	9491082	Phenylalanine- and tyrosine-auxotrophic mutants of Saccharomyces cerevisiae impaired in transamination.

Q24255	BARH1_DROME	Homeobox protein B-H1	10648235	Formation and specification of distal leg segments in Drosophila by dual Bar homeobox genes, BarH1 and BarH2.

Q9ZPX5	DHSA2_ARATH	Succinate dehydrogenase [ubiquinone] flavoprotein subunit 2, mitochondrial	12374303	The four subunits of mitochondrial respiratory complex II are encoded by multiple nuclear genes and targeted to mitochondria in Arabidopsis thaliana.

Q9VJ07	PHLPP_DROME	Protein phosphatase PHLPP-like protein	15808505	PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth.

O46204	ACPCG_DROME	Accessory gland protein CG15841	18085830	Sustained post-mating response in Drosophila melanogaster requires multiple seminal fluid proteins.

O74842	FFT2_SCHPO	Uncharacterized ATP-dependent helicase fft2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q7Z4H7	HAUS6_HUMAN	HAUS augmin-like complex subunit 6	19369198	The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells.

Q7L804	RFIP2_HUMAN	Rab11 family-interacting protein 2	12470645	Rab11-FIP4 interacts with Rab11 in a GTP-dependent manner and its overexpression condenses the Rab11 positive compartment in HeLa cells.

A0MES8	ABI4_ARATH	Ethylene-responsive transcription factor ABI4	9418043	An Arabidopsis mutant showing reduced feedback inhibition of photosynthesis.

P20840	SAG1_YEAST	Alpha-agglutinin	11292808	Interaction of alpha-agglutinin and a-agglutinin, Saccharomyces cerevisiae sexual cell adhesion molecules.

P38261	EXO84_YEAST	Exocyst complex component EXO84	11425851	New roles for the Snp1 and Exo84 proteins in yeast pre-mRNA splicing.

Q9EQ45	V1R46_MOUSE	Vomeronasal type-1 receptor 46	11116090	Sequence diversity and genomic organization of vomeronasal receptor genes in the mouse.

Q9JK38	GNA1_MOUSE	Glucosamine 6-phosphate N-acetyltransferase	10777580	Cloning and characterization of the murine glucosamine-6-phosphate acetyltransferase EMeg32: differential expression and intracellular membrane association.

Q9I7I0	CCNB3_DROME	G2/mitotic-specific cyclin-B3	12620185	The degradation of two mitotic cyclins contributes to the timing of cytokinesis.

Q07960	RHG01_HUMAN	Rho GTPase-activating protein 1	8288572	Characterization of rhoGAP. A GTPase-activating protein for rho- related small GTPases.

Q08742	FMP31_YEAST	Putative thiosulfate sulfurtransferase FMP31, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q8IA42	GALT4_DROME	N-acetylgalactosaminyltransferase 4	12829714	Functional characterization and expression analysis of members of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family from Drosophila melanogaster.

P21917	DRD4_HUMAN	D(4) dopamine receptor	1319557	Multiple dopamine D4 receptor variants in the human population.

P28493	PR5_ARATH	Pathogenesis-related protein 5	1392589	Acquired resistance in Arabidopsis.

P51402	RL37B_YEAST	60S ribosomal protein L37-B	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

O49160	EIF3C_ARATH	Eukaryotic translation initiation factor 3 subunit C	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

Q9NXR7	BRE_HUMAN	BRCA1-A complex subunit BRE	14636569	Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair.

O14223	TVP15_SCHPO	Golgi apparatus membrane protein tvp15	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8WZ82	OVCA2_HUMAN	Ovarian cancer-associated gene 2 protein	11979432	OVCA2 is downregulated and degraded during retinoid-induced apoptosis.

P67430	NEMR_ECOLI	HTH-type transcriptional repressor nemR	18567656	The uncharacterized transcription factor YdhM is the regulator of the nemA gene, encoding N-ethylmaleimide reductase.

P23246	SFPQ_HUMAN	Splicing factor, proline- and glutamine-rich	8449401	Cloning and characterization of PSF, a novel pre-mRNA splicing factor.

Q9NS69	TOM22_HUMAN	Mitochondrial import receptor subunit TOM22 homolog	10982837	Identification and functional analysis of human Tom22 for protein import into mitochondria.

Q04206	TF65_HUMAN	Transcription factor p65	15029197	The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis.

Q9WTX5	SKP1_MOUSE	S-phase kinase-associated protein 1	12140560	E3 ubiquitin ligase that recognizes sugar chains.

Q90XW5	IRX5_XENLA	Iroquois-class homeodomain protein irx-5	19268445	The Xenopus Irx genes are essential for neural patterning and define the border between prethalamus and thalamus through mutual antagonism with the anterior repressors Fezf and Arx.

Q6DWJ6	GP139_HUMAN	Probable G-protein coupled receptor 139	15845401	Molecular cloning and characterization of a novel Gq-coupled orphan receptor GPRg1 exclusively expressed in the central nervous system.

P28321	YJU3_YEAST	Serine hydrolase YJU3	11914276	Subcellular localization of the yeast proteome.

Q20646	CEP1_CAEEL	Transcription factor cep-1	12445383	Caenorhabditis elegans HUS-1 is a DNA damage checkpoint protein required for genome stability and EGL-1-mediated apoptosis.

Q8N163	K1967_HUMAN	Protein KIAA1967	18235501	DBC1 is a negative regulator of SIRT1.

O81445	CNBL1_ARATH	Calcineurin B-like protein 1	10200328	Genes for calcineurin B-like proteins in Arabidopsis are differentially regulated by stress signals.

P17442	PHO81_YEAST	Phosphate system positive regulatory protein PHO81	14562095	Global analysis of protein localization in budding yeast.

Q04767	TVP18_YEAST	Golgi apparatus membrane protein TVP18	14562095	Global analysis of protein localization in budding yeast.

Q8NFZ5	TNIP2_HUMAN	TNFAIP3-interacting protein 2	14653779	The inhibitor ABIN-2 disrupts the interaction of receptor-interacting protein with the kinase subunit IKKgamma to block activation of the transcription factor NF-kappaB and potentiate apoptosis.

Q9NZI6	TF2L1_HUMAN	Transcription factor CP2-like protein 1	10644752	Cloning of factors related to HIV-inducible LBP proteins that regulate steroidogenic factor-1-independent human placental transcription of the cholesterol side-chain cleavage enzyme, P450scc.

P42938	YG4F_YEAST	Uncharacterized kinase YGR205W	14997573	Crystal structure of the YGR205w protein from Saccharomyces cerevisiae: close structural resemblance to E. coli pantothenate kinase.

Q9HBY8	SGK2_HUMAN	Serine/threonine-protein kinase Sgk2	10548550	Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase.

Q92922	SMRC1_HUMAN	SWI/SNF complex subunit SMARCC1	12837248	The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome.

P21917	DRD4_HUMAN	D(4) dopamine receptor	1840645	Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine.

Q558Z2	SUN1_DICDI	Sun domain-containing protein 1	19632001	Dictyostelium Sun1 is a dynamic membrane protein of both nuclear membranes and required for centrosomal association with clustered centromeres.

Q9CZA6	NDE1_MOUSE	Nuclear distribution protein nudE homolog 1	15473967	Mitotic spindle regulation by Nde1 controls cerebral cortical size.

Q13185	CBX3_HUMAN	Chromobox protein homolog 3	8663349	Interaction between an integral protein of the nuclear envelope inner membrane and human chromodomain proteins homologous to Drosophila HP1.

Q9UIF7	MUTYH_HUMAN	A/G-specific adenine DNA glycosylase	8682794	Cloning and sequencing a human homolog (hMYH) of the Escherichia coli mutY gene whose function is required for the repair of oxidative DNA damage.

Q9DC04	RGS3_MOUSE	Regulator of G-protein signaling 3	11034339	C2PA, a new protein expressed during mouse spermatogenesis.

P56706	WNT7B_HUMAN	Protein Wnt-7b	8168088	Differential expression of human Wnt genes 2, 3, 4, and 7B in human breast cell lines and normal and disease states of human breast tissue.

Q92503	S14L1_HUMAN	SEC14-like protein 1	8697811	Isolation and mapping of a human gene (SEC14L), partially homologous to yeast SEC14, that contains a variable number of tandem repeats (VNTR) site in its 3' untranslated region.

O59666	ATU2_SCHPO	Copper-transporting ATPase ccc2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P60484	PTEN_HUMAN	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	10760291	Evidence for regulation of the PTEN tumor suppressor by a membrane- localized multi-PDZ domain containing scaffold protein MAGI-2.

Q6UB28	AMP1D_HUMAN	Methionine aminopeptidase 1D, mitochondrial	14532271	An unusual peptide deformylase features in the human mitochondrial N- terminal methionine excision pathway.

P32455	GBP1_HUMAN	Interferon-induced guanylate-binding protein 1	1715024	Interferon-induced guanylate-binding proteins lack an N(T)KXD consensus motif and bind GMP in addition to GDP and GTP.

P16473	TSHR_HUMAN	Thyrotropin receptor	15775968	Thyrotropin receptor trafficking relies on the hScrib-betaPIX-GIT1- ARF6 pathway.

P23711	HMOX2_RAT	Heme oxygenase 2	2185251	Isolation, characterization, and expression in Escherichia coli of a cDNA encoding rat heme oxygenase-2.

O14804	TAAR5_HUMAN	Trace amine-associated receptor 5	9464258	Cloning of a putative human neurotransmitter receptor expressed in skeletal muscle and brain.

Q03254	FCP1_YEAST	RNA polymerase II subunit A C-terminal domain phosphatase	10445027	An unusual eukaryotic protein phosphatase required for transcription by RNA polymerase II and CTD dephosphorylation in S. cerevisiae.

Q9U9R7	SNAG_DICDI	Gamma-soluble NSF attachment protein	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P42736	RAP23_ARATH	Ethylene-responsive transcription factor RAP2-3	15159625	Arabidopsis Acyl-CoA-binding protein ACBP2 interacts with an ethylene-responsive element-binding protein, AtEBP, via its ankyrin repeats.

Q96P68	OXGR1_HUMAN	2-oxoglutarate receptor 1	12098360	GPR99, a new G protein-coupled receptor with homology to a new subgroup of nucleotide receptors.

P83661	C125_CYPDO	Peptide Cd-125	11306139	Isolation and sequence determination of peptides in the venom of the spider wasp (Cyphononyx dorsalis) guided by matrix-assisted laser desorption/ionization time of flight (MALDI-TOF) mass spectrometry.

Q9UJY5	GGA1_HUMAN	ADP-ribosylation factor-binding protein GGA1	15143060	The trihelical bundle subdomain of the GGA proteins interacts with multiple partners through overlapping but distinct sites.

O74560	RAF2_SCHPO	Rik1-associated factor 2	16157682	The Clr7 and Clr8 directionality factors and the Pcu4 cullin mediate heterochromatin formation in the fission yeast Schizosaccharomyces pombe.

Q9UK59	DBR1_HUMAN	Lariat debranching enzyme	10982890	Human RNA lariat debranching enzyme cDNA complements the phenotypes of Saccharomyces cerevisiae dbr1 and Schizosaccharomyces pombe dbr1 mutants.

Q8N5F7	NKAP_HUMAN	NF-kappa-B-activating protein	19409814	NKAP is a transcriptional repressor of notch signaling and is required for T cell development.

P84839	BR1E_RANSA	Brevinin-1E	16394170	Skin secretions of Rana saharica frogs reveal antimicrobial peptides esculentins-1 and -1B and brevinins-1E and -2EC with novel insulin releasing activity.

Q9ZRF9	RPK1_ARATH	Probable LRR receptor-like serine/threonine-protein kinase RPK1	15772289	Leucine-rich repeat receptor-like kinase1 is a key membrane-bound regulator of abscisic acid early signaling in Arabidopsis.

Q12996	CSTF3_HUMAN	Cleavage stimulation factor subunit 3	7984242	A subunit of the polyadenylation factor CstF is the human homologue of the Drosophila suppressor of forked protein.

Q08648	SG11B_HUMAN	Sperm-associated antigen 11B	10698202	HE2 beta and HE2 gamma, new members of an epididymis-specific family of androgen-regulated proteins in the human.

Q969W9	PMEPA_HUMAN	Transmembrane prostate androgen-induced protein	10873380	A novel androgen-regulated gene, PMEPA1, located on chromosome 20q13 exhibits high level expression in prostate.

O88848	ARL6_MOUSE	ADP-ribosylation factor-like protein 6	10508919	A novel ADP-ribosylation like factor (ARL-6), interacts with the protein-conducting channel SEC61beta subunit.

Q9LVM1	AB25B_ARATH	ABC transporter B family member 25, mitochondrial	11158531	A mutation of the mitochondrial ABC transporter Sta1 leads to dwarfism and chlorosis in the Arabidopsis mutant starik.

P07900	HS90A_HUMAN	Heat shock protein HSP 90-alpha	2527334	Sequence and regulation of a gene encoding a human 89-kilodalton heat shock protein.

Q12382	DGK1_YEAST	CTP-dependent diacylglycerol kinase 1	18458075	An unconventional diacylglycerol kinase that regulates phospholipid synthesis and nuclear membrane growth.

Q9LHD1	AB15B_ARATH	ABC transporter B family member 15	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

O94518	DIC1_SCHPO	Dynein intermediate chain 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9W4S7	MYC_DROME	Myc protein	8929412	Myc and Max homologs in Drosophila.

Q9AE24	RPRY_BACFR	Transcriptional regulatory protein rprY	8469117	Cloning and identification of a two-component signal-transducing regulatory system from Bacteroides fragilis.

Q8IZP9	GPR64_HUMAN	G-protein coupled receptor 64	9150425	Cloning of a human epididymis-specific mRNA, HE6, encoding a novel member of the seven transmembrane-domain receptor superfamily.

O97949	MSPJ_SAGOE	Beta-microseminoprotein J1	10491085	New world, but not old world, monkeys carry several genes encoding beta-microseminoprotein.

Q15208	STK38_HUMAN	Serine/threonine-protein kinase 38	15197186	Mechanism of activation of NDR (nuclear Dbf2-related) protein kinase by the hMOB1 protein.

Q09822	CDC15_SCHPO	Cell division control protein 15	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

Q9SYX7	HA22B_ARATH	HVA22-like protein b	12081371	AtHVA22 gene family in Arabidopsis: phylogenetic relationship, ABA and stress regulation, and tissue-specific expression.

P62878	RBX1_MOUSE	E3 ubiquitin-protein ligase RBX1	12140560	E3 ubiquitin ligase that recognizes sugar chains.

O88884	AKAP1_RAT	A-kinase anchor protein 1, mitochondrial	9722570	Expression of a kinase anchor protein 121 is regulated by hormones in thyroid and testicular germ cells.

D0EL35	CTC1_ARATH	CST complex subunit CTC1	19854131	Conserved telomere maintenance component 1 interacts with STN1 and maintains chromosome ends in higher eukaryotes.

P55060	XPO2_HUMAN	Exportin-2	9323134	Export of importin-alpha from the nucleus is mediated by a specific nuclear transport factor.

Q93WC9	IPT3_ARATH	Adenylate isopentenyltransferase 3, chloroplastic	17062755	Roles of Arabidopsis ATP/ADP isopentenyltransferases and tRNA isopentenyltransferases in cytokinin biosynthesis.

Q9M384	SCR_ARATH	Protein SCARECROW	17446396	An evolutionarily conserved mechanism delimiting SHR movement defines a single layer of endodermis in plants.

P81058	PEN3A_LITVA	Penaeidin-3a	10639333	Penaeidins, antimicrobial peptides with chitin-binding activity, are produced and stored in shrimp granulocytes and released after microbial challenge.

Q9PT68	FXD5B_XENLA	Forkhead box protein D5-B	10781939	Neuroectodermal specification and regionalization of the Spemann organizer in Xenopus.

Q9NYL2	MLTK_HUMAN	Mitogen-activated protein kinase kinase kinase MLT	10924358	Cloning and expression of ZAK, a mixed lineage kinase-like protein containing a leucine-zipper and a sterile-alpha motif.

P47058	TAD2_YEAST	tRNA-specific adenosine deaminase subunit TAD2	10550050	An adenosine deaminase that generates inosine at the wobble position of transfer RNAs.

Q8TCD5	NT5C_HUMAN	5'(3')-deoxyribonucleotidase, cytosolic type	10681516	Mammalian 5'(3')-deoxyribonucleotidase, cDNA cloning, and overexpression of the enzyme in Escherichia coli and mammalian cells.

Q14183	DOC2A_HUMAN	Double C2-like domain-containing protein alpha	18354201	Doc2 alpha and Munc13-4 regulate Ca(2+) -dependent secretory lysosome exocytosis in mast cells.

Q8LGH4	CUL4_ARATH	Cullin-4	18223036	Characterization of Arabidopsis and rice DWD proteins and their roles as substrate receptors for CUL4-RING E3 ubiquitin ligases.

O17581	SCC4_CAEEL	Cohesin loading complex subunit SCC4 homolog	15539489	mau-2 acts cell-autonomously to guide axonal migrations in Caenorhabditis elegans.

P35443	TSP4_HUMAN	Thrombospondin-4	7852353	Characterization of human thrombospondin-4.

P31785	IL2RG_HUMAN	Cytokine receptor common subunit gamma	8266077	Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor.

O94763	RMP_HUMAN	Unconventional prefoldin RPB5 interactor	9819440	RMP, a novel RNA polymerase II subunit 5-interacting protein, counteracts transactivation by hepatitis B virus X protein.

Q08209	PP2BA_HUMAN	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	8392375	Molecular cloning of a full-length cDNA encoding the catalytic subunit of human calmodulin-dependent protein phosphatase (calcineurin A alpha).

P38242	ALG14_YEAST	UDP-N-acetylglucosamine transferase subunit ALG14	15615718	Two proteins homologous to the N- and C-terminal domains of the bacterial glycosyltransferase Murg are required for the second step of dolichyl-linked oligosaccharide synthesis in Saccharomyces cerevisiae.

P52554	PFD6_CAEEL	Probable prefoldin subunit 6	18062952	Efficient chaperone-mediated tubulin biogenesis is essential for cell division and cell migration in C. elegans.

P52906	UNC30_CAEEL	Homeobox protein unc-30	7997265	Control of type-D GABAergic neuron differentiation by C. elegans UNC- 30 homeodomain protein.

Q96RR4	KKCC2_HUMAN	Calcium/calmodulin-dependent protein kinase kinase 2	11395482	Human Ca2+/calmodulin-dependent protein kinase kinase beta gene encodes multiple isoforms that display distinct kinase activity.

P03915	NU5M_HUMAN	NADH-ubiquinone oxidoreductase chain 5	3921850	Six unidentified reading frames of human mitochondrial DNA encode components of the respiratory-chain NADH dehydrogenase.

P0AC86	PHSG_ECOLI	Glycogen phosphorylase	3047129	Alpha-glucan phosphorylase from Escherichia coli. Cloning of the gene, and purification and characterization of the protein.

Q92499	DDX1_HUMAN	ATP-dependent RNA helicase DDX1	18335541	MBNL1 associates with YB-1 in cytoplasmic stress granules.

Q9NQ94	A1CF_HUMAN	APOBEC1 complementation factor	11871661	Identification of domains in apobec-1 complementation factor required for RNA binding and apolipoprotein-B mRNA editing.

P84825	BRK1_ASCTR	Bradykinin	15922344	Bradykinin-related peptides and tryptophyllins in the skin secretions of the most primitive extant frog, Ascaphus truei.

Q62956	ERBB4_RAT	Receptor tyrosine-protein kinase erbB-4	15355992	ErbB4 expression in neural progenitor cells (ST14A) is necessary to mediate neuregulin-1-beta1-induced migration.

O15484	CAN5_HUMAN	Calpain-5	9339374	A new subfamily of vertebrate calpains lacking a calmodulin-like domain: implications for calpain regulation and evolution.

P42580	NKX12_MOUSE	NK1 transcription factor-related protein 2	9748262	Homeodomain-interacting protein kinases, a novel family of co- repressors for homeodomain transcription factors.

Q66HE5	NUAK2_RAT	NUAK family SNF1-like kinase 2	15893879	Regulation of SNARK activity in response to cellular stresses.

Q9SUQ2	CRF2_ARATH	Ethylene-responsive transcription factor CRF2	16832061	A subset of Arabidopsis AP2 transcription factors mediates cytokinin responses in concert with a two-component pathway.

O00338	ST1C2_HUMAN	Sulfotransferase 1C2	9169148	Human sulfotransferase SULT1C1: cDNA cloning, tissue-specific expression, and chromosomal localization.

Q08231	THP1_YEAST	Nuclear mRNA export protein THP1	15311284	Yeast centrin Cdc31 is linked to the nuclear mRNA export machinery.

Q9UUK2	GCN5_SCHPO	Histone acetyltransferase gcn5	11279037	Two WD repeat-containing TATA-binding protein-associated factors in fission yeast that suppress defects in the anaphase-promoting complex.

Q9NRJ3	CCL28_HUMAN	C-C motif chemokine 28	10781587	Identification of a novel chemokine (CCL28), which binds CCR10 (GPR2).

P14785	CCNA_DROME	G2/mitotic-specific cyclin-A	2564316	Expression and function of Drosophila cyclin A during embryonic cell cycle progression.

P38855	PEX18_YEAST	Peroxisomal membrane protein PEX18	9864360	Pex18p and Pex21p, a novel pair of related peroxins essential for peroxisomal targeting by the PTS2 pathway.

P51514	HTF4_RAT	Transcription factor 12	7683670	The helix-loop-helix proteins (salivary-specific cAMP response element-binding proteins) can modulate cAMP-inducible RP4 gene expression in salivary cells.

Q08477	CP4F3_HUMAN	Leukotriene-B(4) omega-hydroxylase 2	8486631	A novel form of cytochrome P-450 family 4 in human polymorphonuclear leukocytes. cDNA cloning and expression of leukotriene B4 omega- hydroxylase.

Q5FVE4	ACBG2_HUMAN	Long-chain-fatty-acid--CoA ligase ACSBG2	16371355	The second member of the human and murine 'bubblegum' family is a testis-and brainstem-specific acyl-CoA synthetase.

Q8WTD3	ATTA_GLOMM	Attacin-A	11886771	Immunopeptides in the defense reactions of Glossina morsitans to bacterial and Trypanosoma brucei brucei infections.

Q9Y5K1	SPO11_HUMAN	Meiotic recombination protein SPO11	10534401	Cloning, characterization, and localization of mouse and human SPO11.

P70126	SIA8E_MOUSE	Alpha-2,8-sialyltransferase 8E	8910600	Molecular cloning and expression of a fifth type of alpha2,8- sialyltransferase (ST8Sia V). Its substrate specificity is similar to that of SAT-V/III, which synthesize GD1c, GT1a, GQ1b and GT3.

O43524	FOXO3_HUMAN	Forkhead box protein O3	10102273	Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor.

Q95460	HMR1_HUMAN	Major histocompatibility complex class I-related gene protein	7624800	A gene outside the human MHC related to classical HLA class I genes.

Q9UBY8	CLN8_HUMAN	Protein CLN8	10861296	The neuronal ceroid lipofuscinosis CLN8 membrane protein is a resident of the endoplasmic reticulum.

Q94125	AGE1_CAEEL	Phosphatidylinositol 3-kinase age-1	8700226	A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans.

Q20655	14332_CAEEL	14-3-3-like protein 2	16777605	C. elegans SIR-2.1 interacts with 14-3-3 proteins to activate DAF-16 and extend life span.

Q9U3V5	TIPT_DROME	Protein tiptop	15936749	A critical role of teashirt for patterning the ventral epidermis is masked by ectopic expression of tiptop, a paralog of teashirt in Drosophila.

O15504	NUPL2_HUMAN	Nucleoporin-like protein 2	10358091	A new nucleoporin-like protein interacts with both HIV-1 Rev nuclear export signal and CRM-1.

Q9HGM8	KU80_SCHPO	ATP-dependent DNA helicase II subunit 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P38792	RRP4_YEAST	Exosome complex component RRP4	8600032	The 3' end of yeast 5.8S rRNA is generated by an exonuclease processing mechanism.

Q9JK48	SHLB1_MOUSE	Endophilin-B1	12456676	Characterization of endophilin B1b, a brain-specific membrane- associated lysophosphatidic acid acyl transferase with properties distinct from endophilin A1.

P53230	MMP37_YEAST	Mitochondrial import protein MMP37	16790493	Characterization of Mmp37p, a Saccharomyces cerevisiae mitochondrial matrix protein with a role in mitochondrial protein import.

O14798	TR10C_HUMAN	Tumor necrosis factor receptor superfamily member 10C	9314565	Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family.

P17676	CEBPB_HUMAN	CCAAT/enhancer-binding protein beta	2112087	A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family.

Q6IFS5	HSN2_HUMAN	Protein HSN2	15060842	Identification of a novel gene (HSN2) causing hereditary sensory and autonomic neuropathy type II through the study of Canadian genetic isolates.

P00762	TRY1_RAT	Anionic trypsin-1	6896710	Two similar but nonallelic rat pancreatic trypsinogens. Nucleotide sequences of the cloned cDNAs.

P40318	DOA10_YEAST	ERAD-associated E3 ubiquitin-protein ligase DOA10	16873066	Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins.

O43424	GRID2_HUMAN	Glutamate receptor delta-2 subunit	9465309	The human glutamate receptor delta 2 gene (GRID2) maps to chromosome 4q22.

P78352	DLG4_HUMAN	Disks large homolog 4	9286702	Human postsynaptic density-95 (PSD95): location of the gene (DLG4) and possible function in nonneural as well as in neural tissues.

Q16586	SGCA_HUMAN	Alpha-sarcoglycan	7663524	Primary adhalinopathy: a common cause of autosomal recessive muscular dystrophy of variable severity.

P36018	YPT52_YEAST	GTP-binding protein YPT52	11943201	Identification of the novel proteins Yip4p and Yip5p as Rab GTPase interacting factors.

P53355	DAPK1_HUMAN	Death-associated protein kinase 1	20389280	The Cullin 3 substrate adaptor KLHL20 mediates DAPK ubiquitination to control interferon responses.

P38862	ATG7_YEAST	Ubiquitin-like modifier-activating enzyme ATG7	10233148	Apg7p/Cvt2p is required for the cytoplasm-to-vacuole targeting, macroautophagy, and peroxisome degradation pathways.

Q10078	PPK13_SCHPO	Serine/threonine-protein kinase ppk13	15821139	Systematic deletion analysis of fission yeast protein kinases.

P09052	VASA1_DROME	ATP-dependent RNA helicase vasa, isoform A	14588248	Fat facets interacts with vasa in the Drosophila pole plasm and protects it from degradation.

Q6LA56	YF4B_SCHPO	Uncharacterized kinase C3H5.11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O43924	PDE6D_HUMAN	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	9570951	Characterization of human and mouse rod cGMP phosphodiesterase delta subunit (PDE6D) and chromosomal localization of the human gene.

Q3E7C1	TFB5_YEAST	RNA polymerase II transcription factor B subunit 5	15220919	Identification of TFB5, a new component of general transcription and DNA repair factor IIH.

P45820	HUR1_YEAST	Putative uncharacterized protein HUR1	12615994	Novel functions of the phosphatidylinositol metabolic pathway discovered by a chemical genomics screen with wortmannin.

Q8K561	OTOAN_MOUSE	Otoancorin	11972037	Otoancorin, an inner ear protein restricted to the interface between the apical surface of sensory epithelia and their overlying acellular gels, is defective in autosomal recessive deafness DFNB22.

P63151	2ABA_HUMAN	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform	1849734	Structure of the 55-kDa regulatory subunit of protein phosphatase 2A: evidence for a neuronal-specific isoform.

Q43125	CRY1_ARATH	Cryptochrome-1	11260718	An Arabidopsis circadian clock component interacts with both CRY1 and phyB.

Q61850	FOXC2_MOUSE	Forkhead box protein C2	9169153	Isolation of the mouse (MFH-1) and human (FKHL 14) mesenchyme fork head-1 genes reveals conservation of their gene and protein structures.

Q9BQA5	HINFP_HUMAN	Histone H4 transcription factor	18850719	The histone gene cell cycle regulator HiNF-P is a unique zinc finger transcription factor with a novel conserved auxiliary DNA-binding motif.

P70232	CHL1_MOUSE	Neural cell adhesion molecule L1-like protein	12391163	Misguided axonal projections, neural cell adhesion molecule 180 mRNA upregulation, and altered behavior in mice deficient for the close homolog of L1.

Q00618	PGTA_YEAST	Geranylgeranyl transferase type-2 subunit alpha	8232541	The mitotic feedback control gene MAD2 encodes the alpha-subunit of a prenyltransferase.

Q9HDU0	YHEH_SCHPO	UPF0742 protein PB2B2.17c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q55274	ISIA_SYNY3	Iron stress-induced chlorophyll-binding protein	15694354	Supercomplexes of IsiA and photosystem I in a mutant lacking subunit PsaL.

O74550	YCVB_SCHPO	Uncharacterized protein C777.11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O43683	BUB1_HUMAN	Mitotic checkpoint serine/threonine-protein kinase BUB1	15723797	Human Bub1 defines the persistent cohesion site along the mitotic chromosome by affecting Shugoshin localization.

O70276	RPE65_RAT	Retinoid isomerohydrolase	9512345	Rat messenger RNA for the retinal pigment epithelium-specific protein RPE65 gradually accumulates in two weeks from late embryonic days.

P16220	CREB1_HUMAN	Cyclic AMP-responsive element-binding protein 1	2974179	Cyclic AMP-responsive DNA-binding protein: structure based on a cloned placental cDNA.

P02538	K2C6A_HUMAN	Keratin, type II cytoskeletal 6A	7543104	Cloning and characterization of multiple human genes and cDNAs encoding highly related type II keratin 6 isoforms.

P40961	PHB1_YEAST	Prohibitin-1	12237468	A structure for the yeast prohibitin complex: structure prediction and evidence from chemical crosslinking and mass spectrometry.

Q06337	EAF1_YEAST	Chromatin modification-related protein EAF1	15353583	Regulation of chromosome stability by the histone H2A variant Htz1, the Swr1 chromatin remodeling complex, and the histone acetyltransferase NuA4.

Q9EST1	GSDMA_MOUSE	Gasdermin-A	10967128	Gasdermin (Gsdm) localizing to mouse chromosome 11 is predominantly expressed in upper gastrointestinal tract but significantly suppressed in human gastric cancer cells.

P35554	FTN_DROME	Flightin	8486738	Flightin, a novel myofibrillar protein of Drosophila stretch- activated muscles.

Q8WZ42	TITIN_HUMAN	Titin	11717165	The complete gene sequence of titin, expression of an unusual ~700 kDa titin isoform and its interaction with obscurin identify a novel Z-line to I-band linking system.

O35473	C1D_MOUSE	Nuclear nucleic acid-binding protein C1D	9469821	cDNA cloning, recombinant expression and characterization of polypetides with exceptional DNA affinity.

P12004	PCNA_HUMAN	Proliferating cell nuclear antigen	9305916	The DNA repair endonuclease XPG binds to proliferating cell nuclear antigen (PCNA) and shares sequence elements with the PCNA-binding regions of FEN-1 and cyclin-dependent kinase inhibitor p21.

P40388	UVI15_SCHPO	UV-induced protein uvi15	8048925	Isolation of UV-inducible transcripts from Schizosaccharomyces pombe.

Q9UBI9	HDC_HUMAN	Headcase protein homolog	11696983	Isolation and characterization of the human gene homologous to the Drosophila headcase (hdc) gene in chromosome bands 6q23-q24, a region of common deletion in human pancreatic cancer.

Q13454	TUSC3_HUMAN	Tumor suppressor candidate 3	12887896	Oligosaccharyltransferase isoforms that contain different catalytic STT3 subunits have distinct enzymatic properties.

Q969H6	POP5_HUMAN	Ribonuclease P/MRP protein subunit POP5	15096576	Mutual interactions between subunits of the human RNase MRP ribonucleoprotein complex.

Q8R415	PKR2_RAT	Prokineticin receptor 2	12054613	Isolation and identification of EG-VEGF/prokineticins as cognate ligands for two orphan G-protein-coupled receptors.

Q62077	PLCG1_MOUSE	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1	19597499	Themis controls thymocyte selection through regulation of T cell antigen receptor-mediated signaling.

Q15878	CAC1E_HUMAN	Voltage-dependent R-type calcium channel subunit alpha-1E	8071363	Structure and functional characterization of neuronal alpha 1E calcium channel subtypes.

Q9NQR8	NDUF4_RAT	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4	14871833	Identification of HRPAP20: a novel phosphoprotein that enhances growth and survival in hormone-responsive tumor cells.

Q9VJ33	NEDD8_DROME	NEDD8	16127432	Neddylation and deneddylation regulate Cul1 and Cul3 protein accumulation.

O43809	CPSF5_HUMAN	Cleavage and polyadenylation specificity factor subunit 5	17172643	Multiple histone deacetylases and the CREB-binding protein regulate pre-mRNA 3'-end processing.

O13961	NDC1_SCHPO	Nuclear envelope protein ndc1	9763447	cut11(+): a gene required for cell cycle-dependent spindle pole body anchoring in the nuclear envelope and bipolar spindle formation in Schizosaccharomyces pombe.

Q9Y2C2	UST_HUMAN	Uronyl 2-sulfotransferase	10187838	Molecular cloning and characterization of a human uronyl 2- sulfotransferase that sulfates iduronyl and glucuronyl residues in dermatan/chondroitin sulfate.

Q99583	MNT_HUMAN	Max-binding protein MNT	9598315	The human ROX gene: genomic structure and mutation analysis in human breast tumors.

Q80U58	PUM2_MOUSE	Pumilio homolog 2	11780640	PUM2, a novel murine puf protein, and its consensus RNA-binding site.

Q96FW1	OTUB1_HUMAN	Ubiquitin thioesterase OTUB1	19211026	Evidence for bidentate substrate binding as the basis for the K48 linkage specificity of otubain 1.

P04762	CATA_RAT	Catalase	3455767	Complete nucleotide sequence of cDNA and deduced amino acid sequence of rat liver catalase.

Q63009	ANM1_RAT	Protein arginine N-methyltransferase 1	8663146	The mammalian immediate-early TIS21 protein and the leukemia- associated BTG1 protein interact with a protein-arginine N- methyltransferase.

Q8I0F4	LIS1_DICDI	Lissencephaly-1 homolog	15800059	Dictyostelium LIS1 is a centrosomal protein required for microtubule/cell cortex interactions, nucleus/centrosome linkage, and actin dynamics.

Q24478	CP190_DROME	Centrosome-associated zinc finger protein CP190	16051175	The centrosomal protein CP190 regulates myosin function during early Drosophila development.

Q9QY24	ZBP1_MOUSE	Z-DNA-binding protein 1	11524677	Structure of the DLM-1-Z-DNA complex reveals a conserved family of Z- DNA-binding proteins.

Q08444	NOB1_YEAST	20S-pre-rRNA D-site endonuclease NOB1	12628929	The path from nucleolar 90S to cytoplasmic 40S pre-ribosomes.

O14023	ELP3_SCHPO	Probable elongator complex protein 3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q15848	ADIPO_HUMAN	Adiponectin	10403784	The human apM-1, an adipocyte-specific gene linked to the family of TNF's and to genes expressed in activated T cells, is mapped to chromosome 1q21.3-q23, a susceptibility locus identified for familial combined hyperlipidemia (FCH).

P38129	TAF5_YEAST	Transcription initiation factor TFIID subunit 5	10788514	Identification of two novel TAF subunits of the yeast Saccharomyces cerevisiae TFIID complex.

P38304	MED8_YEAST	Mediator of RNA polymerase II transcription subunit 8	16885025	Head module control of mediator interactions.

Q93W77	NIFU1_ARATH	NifU-like protein 1, chloroplastic	12553879	Iron-sulphur cluster assembly in plants: distinct NFU proteins in mitochondria and plastids from Arabidopsis thaliana.

Q9Y664	KPTN_HUMAN	Kaptin	10099934	2E4 (kaptin): a novel actin-associated protein from human blood platelets found in lamellipodia and the tips of the stereocilia of the inner ear.

Q9NR09	BIRC6_HUMAN	Baculoviral IAP repeat-containing protein 6	14765125	Nrdp1-mediated degradation of the gigantic IAP, BRUCE, is a novel pathway for triggering apoptosis.

P32598	PP12_YEAST	Serine/threonine-protein phosphatase PP1-2	12477789	The Glc7p-interacting protein Bud14p attenuates polarized growth, pheromone response, and filamentous growth in Saccharomyces cerevisiae.

P11710	FUS1_YEAST	Nuclear fusion protein FUS1	3302672	Two genes required for cell fusion during yeast conjugation: evidence for a pheromone-induced surface protein.

P49715	CEBPA_HUMAN	CCAAT/enhancer-binding protein alpha	7575576	Molecular cloning, sequence, and expression patterns of the human gene encoding CCAAT/enhancer binding protein alpha (C/EBP alpha).

Q95Y72	DSS1_CAEEL	Probable 26S proteasome complex subunit dss-1	18471277	C. elegans dss-1 is functionally conserved and required for oogenesis and larval growth.

P34066	PSA1A_ARATH	Proteasome subunit alpha type-1-A	19453443	ARS5 is a component of the 26S proteasome complex, and negatively regulates thiol biosynthesis and arsenic tolerance in Arabidopsis.

Q8W420	ADO2_ARATH	Adagio protein 2	15937324	Identification of LOV KELCH PROTEIN2 (LKP2)-interacting factors that can recruit LKP2 to nuclear bodies.

P25686	DNJB2_HUMAN	DnaJ homolog subfamily B member 2	1599432	Human homologues of the bacterial heat-shock protein DnaJ are preferentially expressed in neurons.

Q9D424	CABYR_MOUSE	Calcium-binding tyrosine phosphorylation-regulated protein	12801634	Splicing in murine CABYR and its genomic structure.

P11940	PABP1_HUMAN	Polyadenylate-binding protein 1	11997512	Paip1 interacts with poly(A) binding protein through two independent binding motifs.

Q63635	STX6_RAT	Syntaxin-6	8663448	A new syntaxin family member implicated in targeting of intracellular transport vesicles.

Q00994	BEX3_HUMAN	Protein BEX3	2171551	Characterization of three abundant mRNAs from human ovarian granulosa cells.

O95139	NDUB6_HUMAN	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

Q8WWB7	NCUG1_HUMAN	Lysosomal protein NCU-G1	19556463	A gene network regulating lysosomal biogenesis and function.

Q6ZPI3	LCOR_MOUSE	Ligand-dependent corepressor	12560079	Identification and characterization of Mlr1,2: two mouse homologues of Mblk-1, a transcription factor from the honeybee brain.

Q14542	S29A2_HUMAN	Equilibrative nucleoside transporter 2	7639753	A mammalian delayed-early response gene encodes HNP36, a novel, conserved nucleolar protein.

Q5VTR2	BRE1A_HUMAN	E3 ubiquitin-protein ligase BRE1A	16337599	The human homolog of yeast BRE1 functions as a transcriptional coactivator through direct activator interactions.

O49279	SKI15_ARATH	SKP1-interacting partner 15	12795696	Protein interaction analysis of SCF ubiquitin E3 ligase subunits from Arabidopsis.

Q08012	DRK_DROME	Protein enhancer of sevenless 2B	8462098	A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange, Sos.

P17065	SEC2_YEAST	Rab guanine nucleotide exchange factor SEC2	9199166	Sec2p mediates nucleotide exchange on Sec4p and is involved in polarized delivery of post-Golgi vesicles.

O00238	BMR1B_HUMAN	Bone morphogenetic protein receptor type-1B	10051328	Chromosomal localization of three human genes encoding bone morphogenetic protein receptors.

O08522	GOSR1_CRIGR	Golgi SNAP receptor complex member 1	8636227	A v-SNARE implicated in intra-Golgi transport.

Q10222	PTA1_SCHPO	mRNA cleavage and polyadenylation specificity factor complex subunit pta1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9W5E1	RBX1A_DROME	RING-box protein 1A	12850443	Control of protein degradation by E3 ubiquitin ligases in Drosophila eye development.

O35448	PPT2_MOUSE	Lysosomal thioesterase PPT2	11717424	Disruption of PPT1 or PPT2 causes neuronal ceroid lipofuscinosis in knockout mice.

P50570	DYN2_HUMAN	Dynamin-2	7590285	Isolation of an ubiquitously expressed cDNA encoding human dynamin II, a member of the large GTP-binding protein family.

O15504	NUPL2_HUMAN	Nucleoporin-like protein 2	12228227	Docking of HIV-1 Vpr to the nuclear envelope is mediated by the interaction with the nucleoporin hCG1.

P16370	RPB3_YEAST	DNA-directed RNA polymerase II subunit RPB3	2685562	RNA polymerase II subunit RPB3 is an essential component of the mRNA transcription apparatus.

P43256	HMDH2_ARATH	3-hydroxy-3-methylglutaryl-coenzyme A reductase 2	8302869	Arabidopsis thaliana contains two differentially expressed 3-hydroxy- 3-methylglutaryl-CoA reductase genes, which encode microsomal forms of the enzyme.

P29218	IMPA1_HUMAN	Inositol monophosphatase 1	17068342	Spatial expression patterns and biochemical properties distinguish a second myo-inositol monophosphatase IMPA2 from IMPA1.

P61604	CH10_HUMAN	10 kDa heat shock protein, mitochondrial	7916212	Isolation, sequence analysis and characterization of a cDNA encoding human chaperonin 10.

P21246	PTN_HUMAN	Pleiotrophin	2270483	Cloning and expression of a developmentally regulated protein that induces mitogenic and neurite outgrowth activity.

P43246	MSH2_HUMAN	DNA mismatch repair protein Msh2	12414623	Functional alterations of human exonuclease 1 mutants identified in atypical hereditary nonpolyposis colorectal cancer syndrome.

Q86XS8	GOLI_HUMAN	E3 ubiquitin-protein ligase RNF130	16549277	h-Goliath, paralog of GRAIL, is a new E3 ligase protein, expressed in human leukocytes.

P35631	AP1_ARATH	Floral homeotic protein APETALA 1	11283333	Activation of the Arabidopsis B class homeotic genes by APETALA1.

Q84J39	REM1_ARATH	B3 domain-containing protein REM1	11842146	AtREM1, a member of a new family of B3 domain-containing genes, is preferentially expressed in reproductive meristems.

Q99584	S10AD_HUMAN	Protein S100-A13	16145699	Structural interplay between calcium(II) and copper(II) binding to S100A13 protein.

Q9BS26	ERP44_HUMAN	Endoplasmic reticulum resident protein 44	11847130	ERp44, a novel endoplasmic reticulum folding assistant of the thioredoxin family.

Q9C6S7	PMTK_ARATH	Probable methyltransferase PMT20	16618929	Mapping the Arabidopsis organelle proteome.

P35869	AHR_HUMAN	Aryl hydrocarbon receptor	10395741	Interactions of nuclear receptor coactivator/corepressor proteins with the aryl hydrocarbon receptor complex.

Q06787	FMR1_HUMAN	Fragile X mental retardation 1 protein	16407062	The structure of the N-terminal domain of the fragile X mental retardation protein: a platform for protein-protein interaction.

Q12129	NMD4_YEAST	Nonsense-mediated decay protein 4	14562095	Global analysis of protein localization in budding yeast.

Q9U1S7	PKD2_CAEEL	Polycystin-2	15862350	Polycystin-2 accelerates Ca2+ release from intracellular stores in Caenorhabditis elegans.

Q3TIR3	RIC8A_MOUSE	Synembryn-A	16221497	Heterozygous mice with Ric-8 mutation exhibit impaired spatial memory and decreased anxiety.

Q96QU1	PCD15_HUMAN	Protocadherin-15	15537665	Digenic inheritance of deafness caused by mutations in genes encoding cadherin 23 and protocadherin 15 in mice and humans.

Q9M8S8	VTC4_ARATH	Inositol-phosphate phosphatase	19339506	VTC4 is a bifunctional enzyme that affects myoinositol and ascorbate biosynthesis in plants.

Q06287	EMG1_YEAST	Essential for mitotic growth 1	15590835	The small-subunit processome is a ribosome assembly intermediate.

Q92828	COR2A_HUMAN	Coronin-2A	12628926	Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1.

P06213	INSR_HUMAN	Insulin receptor	7537849	Phosphotyrosine-dependent interaction of SHC and insulin receptor substrate 1 with the NPEY motif of the insulin receptor via a novel non-SH2 domain.

P13994	CC130_HUMAN	Coiled-coil domain-containing protein 130	3203696	Alternative mechanisms for gene activation induced by poly(rI).poly(rC) and Newcastle disease virus.

P47128	EAF6_YEAST	Chromatin modification-related protein EAF6	17157260	Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs.

Q7T1K4	ANDR_RANCA	Androgen receptor	13129498	Cloning and characterization of androgen receptor from bullfrog, Rana catesbeiana.

P10862	RAD18_YEAST	Postreplication repair E3 ubiquitin-protein ligase RAD18	7926769	Specific complex formation between yeast RAD6 and RAD18 proteins: a potential mechanism for targeting RAD6 ubiquitin-conjugating activity to DNA damage sites.

P36040	POC2_YEAST	Proteasome assembly chaperone 2	17431397	Beta-subunit appendages promote 20S proteasome assembly by overcoming an Ump1-dependent checkpoint.

Q8NEP3	LRC50_HUMAN	Leucine-rich repeat-containing protein 50	18385425	LRRC50, a conserved ciliary protein implicated in polycystic kidney disease.

P33316	DUT_HUMAN	Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial	8631816	Characterization of distinct nuclear and mitochondrial forms of human deoxyuridine triphosphate nucleotidohydrolase.

Q9NYW4	TA2R5_HUMAN	Taste receptor type 2 member 5	10761934	A novel family of mammalian taste receptors.

P55017	S12A3_HUMAN	Solute carrier family 12 member 3	8528245	Gitelman's variant of Bartter's syndrome, inherited hypokalaemic alkalosis, is caused by mutations in the thiazide-sensitive Na-Cl cotransporter.

P82715	PPD5_ARATH	PsbP domain-containing protein 5, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q13247	SRSF6_HUMAN	Serine/arginine-rich splicing factor 6	7556075	Identification and characterization of three members of the human SR family of pre-mRNA splicing factors.

Q9U6M3	JBP1_TRYBB	Thymine dioxygenase JBP1	17389644	The protein that binds to DNA base J in trypanosomatids has features of a thymidine hydroxylase.

Q9LUN2	YSL5_ARATH	Probable metal-nicotianamine transporter YSL5	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q13822	ENPP2_HUMAN	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	7982964	cDNA cloning of the human tumor motility-stimulating protein, autotaxin, reveals a homology with phosphodiesterases.

Q12962	TAF10_HUMAN	Transcription initiation factor TFIID subunit 10	16415881	Structural basis for the methylation site specificity of SET7/9.

P35449	NHX9_CAEEL	Probable Na(+)/H(+) antiporter nhx-9	8382340	Molecular analysis of two genes between let-653 and let-56 in the unc-22(IV) region of Caenorhabditis elegans.

Q9NPJ1	MKKS_HUMAN	McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin	10802661	Mutation of a gene encoding a putative chaperonin causes McKusick- Kaufman syndrome.

O14788	TNF11_HUMAN	Tumor necrosis factor ligand superfamily member 11	9367155	A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function.

Q7KZF4	SND1_HUMAN	Staphylococcal nuclease domain-containing protein 1	7651391	The Epstein-Barr virus nuclear protein 2 acidic domain forms a complex with a novel cellular coactivator that can interact with TFIIE.

P48484	PP14_ARATH	Serine/threonine-protein phosphatase PP1 isozyme 4	7678768	Expression of multiple type 1 phosphoprotein phosphatases in Arabidopsis thaliana.

Q96QK1	VPS35_HUMAN	Vacuolar protein sorting-associated protein 35	19553991	GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer.

P24853	IBP2_PIG	Insulin-like growth factor-binding protein 2	10601973	Complex mediation of uterine endometrial epithelial cell growth by insulin-like growth factor-II (IGF-II) and IGF-binding protein-2.

Q8CGB3	UACA_MOUSE	Uveal autoantigen with coiled-coil domains and ankyrin repeats	12761289	Identification of a novel, embryonal carcinoma cell-associated molecule, nucling, that is up-regulated during cardiac muscle differentiation.

P34218	SAS3_YEAST	Histone acetyltransferase SAS3	11731478	Histone H3 specific acetyltransferases are essential for cell cycle progression.

Q99MB1	TLR3_MOUSE	Toll-like receptor 3	14993594	Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection.

P19351	TNNT_DROME	Troponin T, skeletal muscle	2124273	Drosophila melanogaster troponin-T mutations engender three distinct syndromes of myofibrillar abnormalities.

P93830	IAA17_ARATH	Auxin-responsive protein IAA17	12036262	Genetics of Aux/IAA and ARF action in plant growth and development.

O14727	APAF_HUMAN	Apoptotic protease-activating factor 1	9267021	Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3.

P69434	PGAA_ECOLI	Poly-beta-1,6-N-acetyl-D-glucosamine export protein	15090514	The pgaABCD locus of Escherichia coli promotes the synthesis of a polysaccharide adhesin required for biofilm formation.

O15460	P4HA2_HUMAN	Prolyl 4-hydroxylase subunit alpha-2	9211872	Cloning of the human prolyl 4-hydroxylase alpha subunit isoform alpha(II) and characterization of the type II enzyme tetramer. The alpha(I) and alpha(II) subunits do not form a mixed alpha(I)alpha(II)beta2 tetramer.

P83168	A2AP_STRCA	Alpha-2-antiplasmin	11435135	Purification and partial characterisation of alpha(2)-antiplasmin and plasmin(ogen) from ostrich plasma.

P27449	VATL_HUMAN	V-type proton ATPase 16 kDa proteolipid subunit	11543633	Cloning, mapping, and characterization of a human homologue of the yeast longevity assurance gene LAG1.

P21709	EPHA1_HUMAN	Ephrin type-A receptor 1	2825356	A novel putative tyrosine kinase receptor encoded by the eph gene.

P53390	MEP3_YEAST	Ammonium transporter MEP3	9234685	A family of ammonium transporters in Saccharomyces cerevisiae.

P32318	THI4_YEAST	Thiazole biosynthetic enzyme, mitochondrial	7941734	Regulation of THI4 (MOL1), a thiamine-biosynthetic gene of Saccharomyces cerevisiae.

Q60641	NR1H4_MOUSE	Bile acid receptor	7760852	Isolation of proteins that interact specifically with the retinoid X receptor: two novel orphan receptors.

Q5T2R2	DPS1_HUMAN	Decaprenyl-diphosphate synthase subunit 1	16262699	Characterization of solanesyl and decaprenyl diphosphate synthases in mice and humans.

Q9FQ04	XRN4_ARATH	5'-3' exoribonuclease 4	11106401	Novel features of the XRN-family in Arabidopsis: evidence that AtXRN4, one of several orthologs of nuclear Xrn2p/Rat1p, functions in the cytoplasm.

Q14244	MAP7_HUMAN	Ensconsin	8408219	Identification and molecular characterization of E-MAP-115, a novel microtubule-associated protein predominantly expressed in epithelial cells.

P43558	OTU1_YEAST	Ubiquitin thioesterase OTU1	14562095	Global analysis of protein localization in budding yeast.

Q9ER71	RHOJ_MOUSE	Rho-related GTP-binding protein RhoJ	10967094	Characterization of TCL, a new GTPase of the Rho family related to TC10 and Cdc42.

P52630	STAT2_HUMAN	Signal transducer and activator of transcription 2	9020188	Stat2 is a transcriptional activator that requires sequence-specific contacts provided by stat1 and p48 for stable interaction with DNA.

P39732	GIP4_YEAST	GLC7-interacting protein 4	16537909	Glc7/protein phosphatase 1 regulatory subunits can oppose the Ipl1/aurora protein kinase by redistributing Glc7.

P78537	BL1S1_HUMAN	Biogenesis of lysosome-related organelles complex 1 subunit 1	15102850	Identification of snapin and three novel proteins (BLOS1, BLOS2, and BLOS3/reduced pigmentation) as subunits of biogenesis of lysosome- related organelles complex-1 (BLOC-1).

O14300	OXA11_SCHPO	Mitochondrial inner membrane protein oxa1-1	10712694	The respiratory gene OXA1 has two fission yeast orthologues which together encode a function essential for cellular viability.

C0LGK4	Y2165_ARATH	Probable LRR receptor-like serine/threonine-protein kinase At2g16250	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P36018	YPT52_YEAST	GTP-binding protein YPT52	8163546	Role of three rab5-like GTPases, Ypt51p, Ypt52p, and Ypt53p, in the endocytic and vacuolar protein sorting pathways of yeast.

P52179	MYOM1_HUMAN	Myomesin-1	7505783	The globular head domain of titin extends into the center of the sarcomeric M band. cDNA cloning, epitope mapping and immunoelectron microscopy of two titin-associated proteins.

Q02606	YP014_YEAST	Uncharacterized protein YPL014W	14562095	Global analysis of protein localization in budding yeast.

P06213	INSR_HUMAN	Insulin receptor	12138094	Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved.

Q7KZN9	COX15_HUMAN	Cytochrome c oxidase assembly protein COX15 homolog	9878253	Identification and characterization of human cDNAs specific to BCS1, PET112, SCO1, COX15, and COX11, five genes involved in the formation and function of the mitochondrial respiratory chain.

Q55BW2	HDA12_DICDI	Histone deacetylase B	19576222	Histone deacetylases regulate multicellular development in the social amoeba Dictyostelium discoideum.

Q9Y7U5	RGF3_SCHPO	Rho1 guanine nucleotide exchange factor 3	15546915	Schizosaccharomyces pombe Rgf3p is a specific Rho1 GEF that regulates cell wall beta-glucan biosynthesis through the GTPase Rho1p.

O33288	PGSA2_MYCTU	Putative CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyl-transferase 2	10889206	Phosphatidylinositol is an essential phospholipid of mycobacteria.

P28324	ELK4_HUMAN	ETS domain-containing protein Elk-4	1339307	Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element.

O70210	CHAD_RAT	Chondroadherin	9461555	Chondroadherin expression changes in skeletal development.

P69428	TATA_ECOLI	Sec-independent protein translocase protein tatA	9649434	Overlapping functions of components of a bacterial Sec-independent protein export pathway.

O49434	AAH_ARATH	Allantoate deiminase, chloroplastic	16496096	AtAAH encodes a protein with allantoate amidohydrolase activity from Arabidopsis thaliana.

Q96T66	NMNA3_HUMAN	Nicotinamide mononucleotide adenylyltransferase 3	16118205	Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms.

Q70G58	NTRC_ORYSJ	Thioredoxin reductase NTRC	15292215	A novel NADPH thioredoxin reductase, localized in the chloroplast, which deficiency causes hypersensitivity to abiotic stress in Arabidopsis thaliana.

Q9HD42	CHM1A_HUMAN	Charged multivesicular body protein 1a	17928862	ESCRT-III recognition by VPS4 ATPases.

Q29122	MYO6_PIG	Myosin-VI	15037754	The unique insert in myosin VI is a structural calcium-calmodulin binding site.

P02786	TFR1_HUMAN	Transferrin receptor protein 1	1871153	Characterization of transferrin receptor released by K562 erythroleukemia cells.

P08247	SYPH_HUMAN	Synaptophysin	1975480	Synaptophysin: structure of the human gene and assignment to the X chromosome in man and mouse.

O43482	MS18B_HUMAN	Protein Mis18-beta	9466265	Using the yeast two-hybrid system to identify human epithelial cell proteins that bind gonococcal Opa proteins: intracellular gonococci bind pyruvate kinase via their Opa proteins and require host pyruvate for growth.

Q80US8	MAD3_MOUSE	Max dimerization protein 3	8521822	Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation.

P50528	PLO1_SCHPO	Serine/threonine-protein kinase plo1	7744248	The conserved Schizosaccharomyces pombe kinase plo1, required to form a bipolar spindle, the actin ring, and septum, can drive septum formation in G1 and G2 cells.

O14227	RDR1_SCHPO	RNA-dependent RNA polymerase 1	12193640	Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi.

Q9FZ45	Y1686_ARATH	Uncharacterized membrane protein At1g16860	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q9VQE7	G23AA_DROME	Putative gustatory receptor 23a, isoforms A/C	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

P49711	CTCF_HUMAN	Transcriptional repressor CTCF	18413740	DNA methyltransferase 1 and 3B activate BAG-1 expression via recruitment of CTCFL/BORIS and modulation of promoter histone methylation.

Q9NZC3	GDE1_HUMAN	Glycerophosphodiester phosphodiesterase 1	10760272	MIR16, a putative membrane glycerophosphodiester phosphodiesterase, interacts with RGS16.

Q8TAF3	WDR48_HUMAN	WD repeat-containing protein 48	19075014	UAF1 is a subunit of multiple deubiquitinating enzyme complexes.

O43085	YHSA_SCHPO	Uncharacterized RING finger protein C947.10	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O08603	RAE1B_MOUSE	Retinoic acid early-inducible protein 1-beta	10894171	Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice.

P53204	NMA2_YEAST	Nicotinamide-nucleotide adenylyltransferase 2	11884393	Manipulation of a nuclear NAD+ salvage pathway delays aging without altering steady-state NAD+ levels.

P28321	YJU3_YEAST	Serine hydrolase YJU3	14645503	Synergistic computational and experimental proteomics approaches for more accurate detection of active serine hydrolases in yeast.

Q03388	VPS72_YEAST	Vacuolar protein sorting-associated protein 72	14690608	A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1.

Q9QYJ6	PDE10_RAT	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	10583409	Striatum- and testis-specific phosphodiesterase PDE10A isolation and characterization of a rat PDE10A.

Q9D1G3	HHATL_MOUSE	Protein-cysteine N-palmitoyltransferase HHAT-like protein	18081866	Mammalian Gup1, a homolog of Saccharomyces cerevisiae glycerol uptake/transporter 1, acts as a negative regulator for N-terminal palmitoylation of Sonic hedgehog.

Q99466	NOTC4_HUMAN	Neurogenic locus notch homolog protein 4	11101851	MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors.

Q08109	HRD1_YEAST	ERAD-associated E3 ubiquitin-protein ligase HRD1	11139575	Membrane topology and function of Der3/Hrd1p as a ubiquitin-protein ligase (E3) involved in endoplasmic reticulum degradation.

P38862	ATG7_YEAST	Ubiquitin-like modifier-activating enzyme ATG7	12965207	The carboxyl terminal 17 amino acids within Apg7 are essential for Apg8 lipidation, but not for Apg12 conjugation.

P57729	RAB38_HUMAN	Ras-related protein Rab-38	10910072	Serological cloning of a melanocyte rab guanosine 5'-triphosphate- binding protein and a chromosome condensation protein from a melanoma complementary DNA library.

P36633	ABP1_RAT	Amiloride-sensitive amine oxidase [copper-containing]	8375402	Molecular cloning and functional expression of different molecular forms of rat amiloride-binding proteins.

Q07523	HAOX2_RAT	Hydroxyacid oxidase 2	8508789	Molecular cloning and nucleotide sequence of cDNA encoding rat kidney long-chain L-2-hydroxy acid oxidase. Expression of the catalytically active recombinant protein as a chimaera.

Q93008	USP9X_HUMAN	Probable ubiquitin carboxyl-terminal hydrolase FAF-X	8922996	The Drosophila developmental gene fat facets has a human homologue in Xp11.4 which escapes X-inactivation and has related sequences on Yq11.2.

P15891	ABP1_YEAST	Actin-binding protein	2405279	Homology of a yeast actin-binding protein to signal transduction proteins and myosin-I.

Q9P6I7	ADA_SCHPO	Adenosine deaminase	14643670	Sub-families of alpha/beta barrel enzymes: a new adenine deaminase family.

Q9H3Q3	G3ST2_HUMAN	Galactose-3-O-sulfotransferase 2	11029462	Molecular cloning and characterization of a human beta-Gal-3'- sulfotransferase that acts on both type 1 and type 2 (Galbeta 1-3/1- 4GlcNAc-R) oligosaccharides.

Q8CID0	CSR2B_MOUSE	Cysteine-rich protein 2-binding protein	19103755	The double-histone-acetyltransferase complex ATAC is essential for mammalian development.

Q63089	S22A1_RAT	Solute carrier family 22 member 1	7990927	Drug excretion mediated by a new prototype of polyspecific transporter.

O96042	DIA2_DICDI	Differentiation-associated protein 2	9813183	Underexpression of a novel gene, dia2, impairs the transition of Dictyostelium cells from growth to differentiation.

P51397	DAP1_HUMAN	Death-associated protein 1	7828849	Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death.

Q03018	ESP1_YEAST	Separin	9635435	An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast.

P92937	CIPKF_ARATH	CBL-interacting serine/threonine-protein kinase 15	10725350	The Arabidopsis SOS2 protein kinase physically interacts with and is activated by the calcium-binding protein SOS3.

Q8NCH0	CHSTE_HUMAN	Carbohydrate sulfotransferase 14	11470797	Molecular cloning and characterization of a dermatan-specific N- acetylgalactosamine 4-O-sulfotransferase.

Q01939	PRS8_YEAST	26S protease regulatory subunit 8 homolog	16284124	An integrated mass spectrometry-based proteomic approach: quantitative analysis of tandem affinity-purified in vivo cross-linked protein complexes (QTAX) to decipher the 26 S proteasome-interacting network.

P0A6A0	UBIB_ECOLI	Probable ubiquinone biosynthesis protein ubiB	9422602	Identification and characterization of aarF, a locus required for production of ubiquinone in Providencia stuartii and Escherichia coli and for expression of 2'-N-acetyltransferase in P. stuartii.

P10663	RT02_YEAST	37S ribosomal protein MRP2, mitochondrial	11278769	Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues.

Q06696	VPS36_YEAST	Vacuolar protein-sorting-associated protein 36	12194858	Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular body.

Q36736	KM11_LEIDO	Kinetoplastid membrane protein 11	7927770	The kinetoplastid membrane protein 11 of Leishmania donovani and African trypanosomes is a potent stimulator of T-lymphocyte proliferation.

Q8WVD3	RN138_HUMAN	E3 ubiquitin-protein ligase RNF138	16714285	NARF, an nemo-like kinase (NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF).

Q9UUH1	VPS55_SCHPO	Vacuolar protein sorting-associated protein 55	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P53237	LST7_YEAST	Protein LST7	9409822	Control of amino acid permease sorting in the late secretory pathway of Saccharomyces cerevisiae by SEC13, LST4, LST7 and LST8.

P48016	ATH1_YEAST	Vacuolar acid trehalase	8764988	Purification and biochemical characterization of the ATH1 gene product, vacuolar acid trehalase, from Saccharomyces cerevisiae.

P40048	PTP3_YEAST	Tyrosine-protein phosphatase 3	9211927	Two protein-tyrosine phosphatases inactivate the osmotic stress response pathway in yeast by targeting the mitogen-activated protein kinase, Hog1.

P53911	EAF7_YEAST	Chromatin modification-related protein EAF7	15353583	Regulation of chromosome stability by the histone H2A variant Htz1, the Swr1 chromatin remodeling complex, and the histone acetyltransferase NuA4.

Q9FZ33	AXR4_ARATH	Protein AUXIN RESPONSE 4	16618929	Mapping the Arabidopsis organelle proteome.

P39904	VPS52_YEAST	Vacuolar protein sorting-associated protein 52	12686613	Vps51p mediates the association of the GARP (Vps52/53/54) complex with the late Golgi t-SNARE Tlg1p.

P53632	PAP2_YEAST	Poly(A) RNA polymerase protein 2	10066793	The topoisomerase-related function gene TRF4 affects cellular sensitivity to the antitumor agent camptothecin.

O74436	SRP68_SCHPO	Signal recognition particle subunit srp68	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P68254	1433T_MOUSE	14-3-3 protein theta	9211421	Molecular cloning and tissue-specific expression of the mouse homologue of the rat brain 14-3-3 theta protein: characterization of its cellular and developmental pattern of expression in the male germ line.

Q12362	RIB2_YEAST	Bifunctional protein RIB2	4555411	Biosynthesis of riboflavine in Saccharomyces cerevisiae: the role of genes rib 1 and rib 7.

P77214	CUSF_ECOLI	Cation efflux system protein cusF	11283292	The product of the ybdE gene of the Escherichia coli chromosome is involved in detoxification of silver ions.

Q505F1	NR2C1_MOUSE	Nuclear receptor subfamily 2 group C member 1	9774688	Cloning and characterization of mouse RIP140, a corepressor for nuclear orphan receptor TR2.

Q05201	EYA_DROME	Developmental protein eyes absent	14628052	Eyes absent represents a class of protein tyrosine phosphatases.

P35996	RM38_YEAST	54S ribosomal protein L38, mitochondrial	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Q8L7D5	THAH_ARATH	Cytochrome P450 708A2	18356490	Metabolic diversification -- independent assembly of operon-like gene clusters in different plants.

P50534	MSL2_DROME	Protein male-specific lethal-2	7781064	Expression of msl-2 causes assembly of dosage compensation regulators on the X chromosomes and female lethality in Drosophila.

Q9UI46	DNAI1_HUMAN	Dynein intermediate chain 1, axonemal	10577904	Loss-of-function mutations in a human gene related to Chlamydomonas reinhardtii dynein IC78 result in primary ciliary dyskinesia.

P92978	RAC11_ARATH	Rac-like GTP-binding protein ARAC11	11283335	A novel UDP-glucose transferase is part of the callose synthase complex and interacts with phragmoplastin at the forming cell plate.

P48960	CD97_HUMAN	CD97 antigen	7636245	Expression cloning and chromosomal mapping of the leukocyte activation antigen CD97, a new seven-span transmembrane molecule of the secretion receptor superfamily with an unusual extracellular domain.

P16471	PRLR_HUMAN	Prolactin receptor	10585417	Functional characterization of the intermediate isoform of the human prolactin receptor.

O60260	PRKN2_HUMAN	E3 ubiquitin-protein ligase parkin	16352719	Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin and mutant LRRK2 induces neuronal degeneration.

P42844	ZIM17_YEAST	Mitochondrial protein import protein ZIM17	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P15907	SIAT1_HUMAN	Beta-galactoside alpha-2,6-sialyltransferase 1	2408023	Complete cDNA sequence encoding human beta-galactoside alpha-2,6- sialyltransferase.

Q8I0P1	SPAST_DROME	Spastin	18202664	Structural basis of microtubule severing by the hereditary spastic paraplegia protein spastin.

Q16719	KYNU_HUMAN	Kynureninase	11985583	Purification and biochemical characterization of some of the properties of recombinant human kynureninase.

O35730	RING1_MOUSE	E3 ubiquitin-protein ligase RING1	15525528	Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation.

O14239	RAX2_SCHPO	Polarized growth protein rax2	17085965	Function of rax2p in the polarized growth of fission yeast.

O74914	YJ73_SCHPO	Uncharacterized protein C757.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O09113	OTP_MOUSE	Homeobox protein orthopedia	17481897	Orthopedia homeodomain protein is essential for diencephalic dopaminergic neuron development.

Q9N658	GFI1_DROME	Zinc finger protein sens	10975525	Senseless, a Zn finger transcription factor, is necessary and sufficient for sensory organ development in Drosophila.

Q6TRW4	PDS5B_RAT	Sister chromatid cohesion protein PDS5 homolog B	12072405	Mechanism of androgen action on cell proliferation: AS3 protein as a mediator of proliferative arrest in the rat prostate.

Q9FGV1	ARFH_ARATH	Auxin response factor 8	16107481	Auxin response factors ARF6 and ARF8 promote jasmonic acid production and flower maturation.

Q9LQ89	ROGF2_ARATH	Rop guanine nucleotide exchange factor 2	15980860	A new family of RhoGEFs activates the Rop molecular switch in plants.

P34162	MED20_YEAST	Mediator of RNA polymerase II transcription subunit 20	16885025	Head module control of mediator interactions.

Q708W1	FXJ1B_XENLA	Forkhead box protein J1-B	14986136	Isolation and developmental expression of Xenopus FoxJ1 and FoxK1.

P20718	GRAH_HUMAN	Granzyme H	2193684	Cloning of a gene that encodes a new member of the human cytotoxic cell protease family.

Q9NFZ3	GBGE_DROME	Guanine nucleotide-binding protein subunit gamma-e	15205461	Targeted mutagenesis of the farnesylation site of Drosophila Ggammae disrupts membrane association of the G protein betagamma complex and affects the light sensitivity of the visual system.

P97464	EXT1_MOUSE	Exostosin-1	10639137	The putative tumor suppressors EXT1 and EXT2 form a stable complex that accumulates in the Golgi apparatus and catalyzes the synthesis of heparan sulfate.

Q9R1M5	NALP5_MOUSE	NACHT, LRR and PYD domains-containing protein 5	18804437	A subcortical maternal complex essential for preimplantation mouse embryogenesis.

P49640	EVX1_HUMAN	Homeobox even-skipped homolog protein 1	1684419	Isolation and mapping of EVX1, a human homeobox gene homologous to even-skipped, localized at the 5' end of HOX1 locus on chromosome 7.

Q80VC6	TSAP1_MOUSE	tRNA selenocysteine 1-associated protein 1	16230358	Evidence for direct roles of two additional factors, SECp43 and soluble liver antigen, in the selenoprotein synthesis machinery.

P38883	RIX1_YEAST	Pre-rRNA-processing protein RIX1	15528184	Rea1, a dynein-related nuclear AAA-ATPase, is involved in late rRNA processing and nuclear export of 60 S subunits.

Q14938	NFIX_HUMAN	Nuclear factor 1 X-type	7937100	Cloning and functional analysis of spliced isoforms of human nuclear factor I-X: interference with transcriptional activation by NFI/CTF in a cell-type specific manner.

Q9VBW6	DAN_DROME	Protein distal antenna	12571108	Distal antenna and distal antenna related encode nuclear proteins containing pipsqueak motifs involved in antenna development in Drosophila.

Q924C5	ALPK3_MOUSE	Alpha-protein kinase 3	11418590	A novel myocyte-specific gene midori promotes the differentiation of P19CL6 cells into cardiomyocytes.

Q9YH09	RALBA_XENLA	Ras-related protein ralB-A	15511640	RLIP mediates downstream signalling from RalB to the actin cytoskeleton during Xenopus early development.

Q9LVL5	WNK4_ARATH	Probable serine/threonine-protein kinase WNK4	12506983	Compilation and characterization of a novel WNK family of protein kinases in Arabiodpsis thaliana with reference to circadian rhythms.

Q9FJ80	P2A14_ARATH	F-box protein PP2-A14	12795696	Protein interaction analysis of SCF ubiquitin E3 ligase subunits from Arabidopsis.

Q8GYY0	1A112_ARATH	Probable aminotransferase ACS12	12968022	Biochemical diversity among the 1-amino-cyclopropane-1-carboxylate synthase isozymes encoded by the Arabidopsis gene family.

Q11117	LMP1_CAEEL	LAMP family protein lmp-1	10862717	Identification and molecular-genetic characterization of a LAMP/CD68- like protein from Caenorhabditis elegans.

Q7Z7M1	GP144_HUMAN	Probable G-protein coupled receptor 144	15203201	The human and mouse repertoire of the adhesion family of G-protein- coupled receptors.

P87234	GYP3_SCHPO	GTPase-activating protein gyp3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q56WD9	THIK2_ARATH	3-ketoacyl-CoA thiolase 2, peroxisomal	11696182	Requirement for 3-ketoacyl-CoA thiolase-2 in peroxisome development, fatty acid beta-oxidation and breakdown of triacylglycerol in lipid bodies of Arabidopsis seedlings.

Q8I5Z5	YPF09_PLAF7	Uncharacterized protein PFL0250w	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

Q8IVI9	NOSTN_HUMAN	Nostrin	16807357	Translocation of endothelial nitric-oxide synthase involves a ternary complex with caveolin-1 and NOSTRIN.

O00155	GPR25_HUMAN	Probable G-protein coupled receptor 25	9020062	Discovery of a novel human G protein-coupled receptor gene (GPR25) located on chromosome 1.

Q2TAK8	MUM1_HUMAN	PWWP domain-containing protein MUM1	20347427	Regulation of chromatin architecture by the PWWP domain-containing DNA damage-responsive factor EXPAND1/MUM1.

Q969Q5	RAB24_HUMAN	Ras-related protein Rab-24	16034420	Structural basis of family-wide Rab GTPase recognition by rabenosyn- 5.

P39007	STT3_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3	10677492	Studies on the role of the hydrophobic domain of Ost4p in interactions with other subunits of yeast oligosaccharyl transferase.

Q9PVZ3	FXC1A_XENLA	Forkhead box protein C1-A	17705306	The role of FoxC1 in early Xenopus development.

P62753	RS6_HUMAN	40S ribosomal protein S6	1301164	The organization of the intron-containing human S6 ribosomal protein (rpS6) gene and determination of its location at chromosome 9p21.

P0ADC1	LPTE_ECOLI	LPS-assembly lipoprotein lptE	16861298	Identification of a protein complex that assembles lipopolysaccharide in the outer membrane of Escherichia coli.

O74958	MMI1_SCHPO	YTH domain-containing protein mmi1	16823445	Selective elimination of messenger RNA prevents an incidence of untimely meiosis.

P70423	CTR3_MOUSE	Cationic amino acid transporter 3	9334265	A new member of the cationic amino acid transporter family is preferentially expressed in adult mouse brain.

Q8R5J9	PRAF3_MOUSE	PRA1 family protein 3	10508919	A novel ADP-ribosylation like factor (ARL-6), interacts with the protein-conducting channel SEC61beta subunit.

O52623	SOPE_SALTY	Guanine nucleotide exchange factor sopE	12093730	Structural basis for the reversible activation of a Rho protein by the bacterial toxin SopE.

P68036	UB2L3_HUMAN	Ubiquitin-conjugating enzyme E2 L3	19340006	The ubiquitin ligase Triad1 inhibits myelopoiesis through UbcH7 and Ubc13 interacting domains.

O60057	MU147_SCHPO	Meiotically up-regulated gene 147 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9U2Q9	GSK3_CAEEL	Glycogen synthase kinase-3	15572126	Multiple Wnt signaling pathways converge to orient the mitotic spindle in early C. elegans embryos.

Q9SEE5	GALK1_ARATH	Galactokinase	9225860	Isolation of a cDNA encoding an Arabidopsis galactokinase by functional expression in yeast.

P23497	SP100_HUMAN	Nuclear autoantigen Sp-100	15882967	The mammalian heterochromatin protein 1 binds diverse nuclear proteins through a common motif that targets the chromoshadow domain.

Q9UBU7	DBF4A_HUMAN	Protein DBF4 homolog A	10373557	A novel growth- and cell cycle-regulated protein, ASK, activates human Cdc7-related kinase and is essential for G1/S transition in mammalian cells.

P30941	SPI7_SOLTU	Serine protease inhibitor 7	1515078	Characterization of aspartic proteinase inhibitors from potato at the gene, cDNA and protein levels.

P21333	FLNA_HUMAN	Filamin-A	16076904	The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins.

Q03954	SPC19_YEAST	DASH complex subunit SPC19	15640796	The yeast DASH complex forms closed rings on microtubules.

Q9NQ66	PLCB1_HUMAN	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1	10760467	Identification and chromosomal localisation by fluorescence in situ hybridisation of human gene of phosphoinositide-specific phospholipase C beta 1.

P36060	MCR1_YEAST	NADH-cytochrome b5 reductase 2	11420140	Mitochondrial NADH-cytochrome b(5) reductase plays a crucial role in the reduction of D-erythroascorbyl free radical in Saccharomyces cerevisiae.

P09326	CD48_HUMAN	CD48 antigen	2828034	Molecular cloning of the lymphocyte activation marker Blast-1.

P61374	ISL1_RAT	Insulin gene enhancer protein ISL-1	1691825	Insulin gene enhancer binding protein Isl-1 is a member of a novel class of proteins containing both a homeo- and a Cys-His domain.

P26781	RS11_YEAST	40S ribosomal protein S11	8070651	Reduced dosage of genes encoding ribosomal protein S18 suppresses a mitochondrial initiation codon mutation in Saccharomyces cerevisiae.

Q9D8U4	C1QT2_MOUSE	Complement C1q tumor necrosis factor-related protein 2	15231994	A family of Acrp30/adiponectin structural and functional paralogs.

P22352	GPX3_HUMAN	Glutathione peroxidase 3	8056346	The human plasma glutathione peroxidase-encoding gene: organization, sequence and localization to chromosome 5q32.

O54980	SNG2_RAT	Synaptogyrin-2	12928441	Cellugyrin and synaptogyrin facilitate targeting of synaptophysin to a ubiquitous synaptic vesicle-sized compartment in PC12 cells.

P10176	COX8A_HUMAN	Cytochrome c oxidase subunit 8A, mitochondrial	2543673	A gene specifying subunit VIII of human cytochrome c oxidase is localized to chromosome 11 and is expressed in both muscle and non- muscle tissues.

Q86SE8	NPM2_HUMAN	Nucleoplasmin-2	12714744	Roles of NPM2 in chromatin and nucleolar organization in oocytes and embryos.

P05095	ACTNA_DICDI	Alpha-actinin A	8486739	The Ca(2+)-binding domains in non-muscle type alpha-actinin: biochemical and genetic analysis.

O14460	EF2_SCHPO	Elongation factor 2	9099890	Comprehensive cloning of Schizosaccharomyces pombe genes encoding translation elongation factors.

Q9Y4K3	TRAF6_HUMAN	TNF receptor-associated factor 6	11751921	A novel zinc finger protein that inhibits osteoclastogenesis and the function of tumor necrosis factor receptor-associated factor 6.

Q9R0Q2	LT4R1_RAT	Leukotriene B4 receptor 1	10471406	Cloning and characterization of rat leukotriene B4 receptor.

P32341	VPH2_YEAST	Vacuolar ATPase assembly integral membrane protein VPH2	9325326	VMA12 encodes a yeast endoplasmic reticulum protein required for vacuolar H+-ATPase assembly.

O17695	HDA1_CAEEL	Histone deacetylase 1	11742996	A POP-1 repressor complex restricts inappropriate cell type-specific gene transcription during Caenorhabditis elegans embryogenesis.

Q15773	MLF2_HUMAN	Myeloid leukemia factor 2	8661158	cDNA cloning, tissue distribution, and chromosomal localization of myelodysplasia/myeloid leukemia factor 2 (MLF2).

Q9H2R5	KLK15_HUMAN	Kallikrein-15	11010966	Molecular cloning of the human kallikrein 15 gene (KLK15). Up- regulation in prostate cancer.

Q07912	ACK1_HUMAN	Activated CDC42 kinase 1	8497321	A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42.

P70662	LDB1_MOUSE	LIM domain-binding protein 1	8876198	Nuclear LIM interactor, a rhombotin and LIM homeodomain interacting protein, is expressed early in neuronal development.

Q7Z4H7	HAUS6_HUMAN	HAUS augmin-like complex subunit 6	19427217	HAUS, the 8-subunit human augmin complex, regulates centrosome and spindle integrity.

P43577	GNA1_YEAST	Glucosamine 6-phosphate N-acetyltransferase	9867860	Saccharomyces cerevisiae GNA1, an essential gene encoding a novel acetyltransferase involved in UDP-N-acetylglucosamine synthesis.

Q9NWU1	OXSM_HUMAN	3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial	15668256	Cloning, expression, and characterization of the human mitochondrial beta-ketoacyl synthase. Complementation of the yeast CEM1 knock-out strain.

P23467	PTPRB_HUMAN	Receptor-type tyrosine-protein phosphatase beta	2170109	Structural diversity and evolution of human receptor-like protein tyrosine phosphatases.

P05771	KPCB_HUMAN	Protein kinase C beta type	3755548	Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways.

Q058N4	MRS2B_ARATH	Magnesium transporter MRS2-11, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q9JJ89	CCD86_MOUSE	Coiled-coil domain-containing protein 86	17300783	Redundant promoter elements mediate IL-3-induced expression of a novel cytokine-inducible gene, cyclon.

O94768	ST17B_HUMAN	Serine/threonine-protein kinase 17B	9786912	DRAKs, novel serine/threonine kinases related to death-associated protein kinase that trigger apoptosis.

P21399	ACOC_HUMAN	Cytoplasmic aconitate hydratase	1946430	A regulated RNA binding protein also possesses aconitase activity.

P40874	MTOX_ECOLI	N-methyl-L-tryptophan oxidase	10220347	Structure of the flavocoenzyme of two homologous amine oxidases: monomeric sarcosine oxidase and N-methyltryptophan oxidase.

Q64349	MAL_RAT	Myelin and lymphocyte protein	7643216	Characterization of a rat gene, rMAL, encoding a protein with four hydrophobic domains in central and peripheral myelin.

P47890	OR1G1_HUMAN	Olfactory receptor 1G1	8004088	Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire.

Q13557	KCC2D_HUMAN	Calcium/calmodulin-dependent protein kinase type II subunit delta	9060999	Identification of novel human tumor cell-specific CaMK-II variants.

P37344	PSPF_ECOLI	Psp operon transcriptional activator	15485810	Identification of a new member of the phage shock protein response in Escherichia coli, the phage shock protein G (PspG).

P27680	COQ3_YEAST	Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P55316	FOXG1_HUMAN	Forkhead box protein G1	12657635	Human PLU-1 has transcriptional repression properties and interacts with the developmental transcription factors BF-1 and PAX9.

P33200	PDR3_YEAST	Transcription factor PDR3	8078477	PDR3, a new yeast regulatory gene, is homologous to PDR1 and controls the multidrug resistance phenomenon.

Q9UL18	AGO1_HUMAN	Protein argonaute-1	19167051	Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs.

Q62716	DEF1_RAT	Neutrophil antibiotic peptide NP-1	7594610	Rat neutrophil defensins. Precursor structures and expression during neutrophilic myelopoiesis.

P30882	CCL5_MOUSE	C-C motif chemokine 5	1375672	Isolation and characterization of cDNA from renal tubular epithelium encoding murine Rantes.

Q9LYT1	PAO3_ARATH	Polyamine oxidase 3	18583528	Bridging the gap between plant and mammalian polyamine catabolism: a novel peroxisomal polyamine oxidase responsible for a full back- conversion pathway in Arabidopsis thaliana.

Q94F62	BAK1_ARATH	BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1	18667726	Arabidopsis SOMATIC EMBRYOGENESIS RECEPTOR KINASE proteins serve brassinosteroid-dependent and -independent signaling pathways.

Q86UR5	RIMS1_HUMAN	Regulating synaptic membrane exocytosis protein 1	11438518	Direct interaction of the Rab3 effector RIM with Ca2+ channels, SNAP- 25, and synaptotagmin.

Q9IAK1	ESR2_ICTPU	Estrogen receptor beta	10753576	Phylogenetic sequence analysis, recombinant expression, and tissue distribution of a channel catfish estrogen receptor beta.

Q9Z2V9	CCNI_MOUSE	Cyclin-I	11054536	In vivo expression and genomic organization of the mouse cyclin I gene (Ccni).

P35582	FOXA1_MOUSE	Hepatocyte nuclear factor 3-alpha	15987773	Forkhead box A1 regulates prostate ductal morphogenesis and promotes epithelial cell maturation.

Q95XP4	SEM2A_CAEEL	Semaphorin-2A	10648234	mab-20 encodes Semaphorin-2a and is required to prevent ectopic cell contacts during epidermal morphogenesis in Caenorhabditis elegans.

Q8TC36	SUN5_HUMAN	SUN domain-containing protein 5	12621555	Cloning of cDNA of TSARG4, a human spermatogenesis related gene.

Q9S9K9	MYB3_ARATH	Transcription factor MYB3	16463103	The MYB transcription factor superfamily of Arabidopsis: expression analysis and phylogenetic comparison with the rice MYB family.

Q9HAU4	SMUF2_HUMAN	E3 ubiquitin-protein ligase SMURF2	11163210	Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF-beta receptor for degradation.

Q9JKC0	CCL24_MOUSE	C-C motif chemokine 24	11067944	Murine eotaxin-2: a constitutive eosinophil chemokine induced by allergen challenge and IL-4 overexpression.

P53855	ATG2_YEAST	Autophagy-related protein 2	11382760	Apg2 is a novel protein required for the cytoplasm to vacuole targeting, autophagy, and pexophagy pathways.

P42126	D3D2_HUMAN	3,2-trans-enoyl-CoA isomerase, mitochondrial	7829074	Human mitochondrial 3,2-trans-enoyl-CoA isomerase (DCI): gene structure and localization to chromosome 16p13.3.

O73692	EGR1_COTJA	Early growth response protein 1	9501495	Evolutionary conservation of the immediate-early gene ZENK.

Q9HGM2	GET1_SCHPO	Protein get1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P38279	RTC2_YEAST	Protein RTC2	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

O75643	U520_HUMAN	U5 small nuclear ribonucleoprotein 200 kDa helicase	9539711	The human U5-200kD DEXH-box protein unwinds U4/U6 RNA duplices in vitro.

P10355	PT122_YEAST	Protein PET122, mitochondrial	8389363	COX3 mRNA-specific translational activator proteins are associated with the inner mitochondrial membrane in Saccharomyces cerevisiae.

O42839	APC4_SCHPO	Anaphase-promoting complex subunit 4	10526233	Fission yeast APC/cyclosome subunits, Cut20/Apc4 and Cut23/Apc8, in regulating metaphase-anaphase progression and cellular stress responses.

O88339	EPN1_RAT	Epsin-1	12353027	Curvature of clathrin-coated pits driven by epsin.

P25398	RS12_HUMAN	40S ribosomal protein S12	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

Q9JLS4	SFRP4_RAT	Secreted frizzled-related protein 4	9409757	DDC-4, an apoptosis-associated gene, is a secreted frizzled relative.

Q2I0E5	PDZD6_XENLA	PDZ domain-containing protein 6	16493421	Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling.

P24813	YAP2_YEAST	AP-1-like transcription activator YAP2	9372930	Yap, a novel family of eight bZIP proteins in Saccharomyces cerevisiae with distinct biological functions.

Q9UT46	MOC3_SCHPO	Transcriptional regulatory protein moc3	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

Q54I71	AARA_DICDI	Protein aardvark	18164290	Screening of genes involved in cell migration in Dictyostelium.

Q925Q9	SH3K1_RAT	SH3 domain-containing kinase-binding protein 1	11152963	SETA is a multifunctional adapter protein with three SH3 domains that binds Grb2, Cbl, and the novel SB1 proteins.

P46595	UBC4_SCHPO	Ubiquitin-conjugating enzyme E2 4	7698660	Schizosaccharomyces pombe and Candida albicans cDNA homologues of the Saccharomyces cerevisiae UBC4 gene.

O60902	SHOX2_HUMAN	Short stature homeobox protein 2	9482898	SHOT, a SHOX-related homeobox gene, is implicated in craniofacial, brain, heart, and limb development.

P26659	RAD15_SCHPO	DNA repair helicase rad15	1319571	Cloning and characterisation of the S. pombe rad15 gene, a homologue to the S. cerevisiae RAD3 and human ERCC2 genes.

Q9SV36	ARK1_ARATH	Armadillo repeat-containing kinesin-like protein 1	17957256	A mutation in MRH2 kinesin enhances the root hair tip growth defect caused by constitutively activated ROP2 small GTPase in Arabidopsis.

P40154	IES2_YEAST	Ino eighty subunit 2	14562095	Global analysis of protein localization in budding yeast.

O35625	AXN1_MOUSE	Axin-1	17681137	A beta-catenin-independent dorsalization pathway activated by Axin/JNK signaling and antagonized by aida.

P34978	TA2R_RAT	Thromboxane A2 receptor	7635958	Rat kidney thromboxane receptor: molecular cloning, signal transduction, and intrarenal expression localization.

Q9JMB7	PIWL1_MOUSE	Piwi-like protein 1	16787967	Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway?

P97298	PEDF_MOUSE	Pigment epithelium-derived factor	9614124	Isolation, purification and characterization of a collagen-associated serpin, caspin, produced by murine colon adenocarcinoma cells.

P35631	AP1_ARATH	Floral homeotic protein APETALA 1	16679456	AGL24, SHORT VEGETATIVE PHASE, and APETALA1 redundantly control AGAMOUS during early stages of flower development in Arabidopsis.

Q01532	BLH1_YEAST	Cysteine proteinase 1, mitochondrial	8063738	Yeast bleomycin hydrolase is a DNA-binding cysteine protease. Identification, purification, biochemical characterization.

Q06639	RSC3_YEAST	Chromatin structure-remodeling complex protein RSC3	16204215	The RSC chromatin remodeling complex bears an essential fungal- specific protein module with broad functional roles.

O88908	SOAT2_MOUSE	Sterol O-acyltransferase 2	9756919	ACAT-2, a second mammalian acyl-CoA:cholesterol acyltransferase. Its cloning, expression, and characterization.

Q8N539	FBCD1_HUMAN	Fibrinogen C domain-containing protein 1	19710473	Characterization of FIBCD1 as an acetyl group-binding receptor that binds chitin.

Q9UKL6	PPCT_HUMAN	Phosphatidylcholine transfer protein	10542325	Cloning, tissue-specific expression, gene structure and chromosomal localization of human phosphatidylcholine transfer protein.

P97527	CNTN5_RAT	Contactin-5	8945756	Novel neural adhesion molecules in the contactin/F3 subgroup of the immunoglobulin superfamily: isolation and characterization of cDNAs from rat brain.

Q9UPT9	UBP22_HUMAN	Ubiquitin carboxyl-terminal hydrolase 22	18206973	The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression.

P55773	CCL23_HUMAN	C-C motif chemokine 23	9104803	Molecular and functional characterization of two novel human C-C chemokines as inhibitors of two distinct classes of myeloid progenitors.

O75366	AVIL_HUMAN	Advillin	9664034	Advillin (p92): a new member of the gelsolin/villin family of actin regulatory proteins.

P07108	ACBP_HUMAN	Acyl-CoA-binding protein	3020548	Cloning and expression of cDNA for human diazepam binding inhibitor, a natural ligand of an allosteric regulatory site of the gamma- aminobutyric acid type A receptor.

Q20405	SRA10_CAEEL	Serpentine receptor class alpha-10	7585938	Divergent seven transmembrane receptors are candidate chemosensory receptors in C. elegans.

P52012	CYP4_CAEEL	Peptidyl-prolyl cis-trans isomerase 4	8111975	More mog genes that influence the switch from spermatogenesis to oogenesis in the hermaphrodite germ line of Caenorhabditis elegans.

P28339	DPOD1_BOVIN	DNA polymerase delta catalytic subunit	10751307	Identification of a fourth subunit of mammalian DNA polymerase delta.

Q03327	UGO1_YEAST	Mitochondrial fusion and transport protein UGO1	11257114	UGO1 encodes an outer membrane protein required for mitochondrial fusion.

Q16740	CLPP_HUMAN	Putative ATP-dependent Clp protease proteolytic subunit, mitochondrial	8543061	Human ClpP protease: cDNA sequence, tissue-specific expression and chromosomal assignment of the gene.

O81821	HFA1B_ARATH	Heat stress transcription factor A-1b	9645433	HSF3, a new heat shock factor from Arabidopsis thaliana, derepresses the heat shock response and confers thermotolerance when overexpressed in transgenic plants.

P83860	OX26_RAT	Orexigenic neuropeptide QRFP	12960173	A new peptidic ligand and its receptor regulating adrenal function in rats.

P30508	1C12_HUMAN	HLA class I histocompatibility antigen, Cw-12 alpha chain	2787363	The structure and expression of genes encoding serologically undetected HLA-C locus antigens.

P38207	APN2_YEAST	DNA-(apurinic or apyrimidinic site) lyase 2	10806210	Apurinic endonuclease activity of yeast Apn2 protein.

Q9ZU49	LPP1_ARATH	Lipid phosphate phosphatase 1	11278556	Lipid phosphate phosphatases in Arabidopsis. Regulation of the AtLPP1 gene in response to stress.

Q7KRY6	NHK1_DROME	Nucleosomal histone kinase 1	16301329	The conserved kinase NHK-1 is essential for mitotic progression and unifying acentrosomal meiotic spindles in Drosophila melanogaster.

P53224	ORM1_YEAST	Protein ORM1	20182505	Orm family proteins mediate sphingolipid homeostasis.

O14013	RRN5_SCHPO	RNA polymerase I-specific transcription initiation factor rrn5	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q6NPP4	CMTA2_ARATH	Calmodulin-binding transcription activator 2	12218065	A calmodulin-binding/CGCG box DNA-binding protein family involved in multiple signaling pathways in plants.

P84268	DAH52_LITDA	Dahlein-5.2	11555873	Bioactive dahlein peptides from the skin secretions of the Australian aquatic frog Litoria dahlii: sequence determination by electrospray mass spectrometry.

Q56WN1	GLN11_ARATH	Glutamine synthetase cytosolic isozyme 1-1	14757761	Kinetic properties and ammonium-dependent regulation of cytosolic isoenzymes of glutamine synthetase in Arabidopsis.

P30874	SSR2_HUMAN	Somatostatin receptor type 2	1346068	Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney.

Q6GLY5	M89BB_XENLA	Cell cycle regulator Mat89Bb homolog	15737938	Drosophila genome-scale screen for PAN GU kinase substrates identifies Mat89Bb as a cell cycle regulator.

Q940D0	ARR1_ARATH	Two-component response regulator ARR1	11135105	Arabidopsis ARR1 and ARR2 response regulators operate as transcriptional activators.

O15446	RPA34_HUMAN	DNA-directed RNA polymerase I subunit RPA34	10373416	CAST, a novel CD3epsilon-binding protein transducing activation signal for interleukin-2 production in T cells.

Q03924	ZN117_HUMAN	Zinc finger protein 117	2505992	The human genome contains hundreds of genes coding for finger proteins of the Kruppel type.

Q8VZ40	PUB14_ARATH	U-box domain-containing protein 14	15231834	Structure and biochemical function of a prototypical Arabidopsis U- box domain.

O95461	LARGE_HUMAN	Glycosyltransferase-like protein LARGE1	9892679	The human LARGE gene from 22q12.3-q13.1 is a new, distinct member of the glycosyltransferase gene family.

Q02094	RHAG_HUMAN	Ammonium transporter Rh type A	1417776	Isolation of cDNA clones for a 50 kDa glycoprotein of the human erythrocyte membrane associated with Rh (rhesus) blood-group antigen expression.

Q9NZN8	CNOT2_HUMAN	CCR4-NOT transcription complex subunit 2	10637334	Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits.

P27692	SPT5_YEAST	Transcription elongation factor SPT5	9450930	Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae.

P56546	CTBP2_MOUSE	C-terminal-binding protein 2	10567582	Identification of CtBP1 and CtBP2 as corepressors of zinc finger- homeodomain factor deltaEF1.

P38705	SYSM_YEAST	Seryl-tRNA synthetase, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

Q9UQQ1	NALDL_HUMAN	N-acetylated-alpha-linked acidic dipeptidase-like protein	9388249	Cloning and characterization of a novel peptidase from rat and human ileum.

P62960	YBOX1_MOUSE	Nuclease-sensitive element-binding protein 1	19470752	Three proteins of the U7-specific Sm ring function as the molecular ruler to determine the site of 3'-end processing in mammalian histone pre-mRNA.

Q09763	GEF1_SCHPO	Rho guanine nucleotide exchange factor gef1	12529446	Gef1p, a new guanine nucleotide exchange factor for Cdc42p, regulates polarity in Schizosaccharomyces pombe.

P29074	PTN4_HUMAN	Tyrosine-protein phosphatase non-receptor type 4	1648233	Identification, cloning, and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to cytoskeletal protein 4.1.

Q9T095	OPT6_ARATH	Oligopeptide transporter 6	11788749	An oligopeptide transporter gene family in Arabidopsis.

Q9R1V6	ADA22_MOUSE	Disintegrin and metalloproteinase domain-containing protein 22	18974846	LGI1 and LGI4 bind to ADAM22, ADAM23 and ADAM11.

Q15223	PVRL1_HUMAN	Poliovirus receptor-related protein 1	9616127	Entry of alphaherpesviruses mediated by poliovirus receptor-related protein 1 and poliovirus receptor.

P16086	SPTA2_RAT	Spectrin alpha chain, brain	2753883	Cloning and analysis of cDNA clones for rat kidney alpha-spectrin.

P63208	SKP1_HUMAN	S-phase kinase-associated protein 1	12820959	Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase.

P62256	UBE2H_HUMAN	Ubiquitin-conjugating enzyme E2 H	8132613	A human ubiquitin-conjugating enzyme homologous to yeast UBC8.

P85213	DEF1_GALME	Defensin	17194500	Purification and characterization of eight peptides from Galleria mellonella immune hemolymph.

O80931	AS1_ARATH	Transcription factor AS1	16243907	Maize rough sheath2 and its Arabidopsis orthologue ASYMMETRIC LEAVES1 interact with HIRA, a predicted histone chaperone, to maintain knox gene silencing and determinacy during organogenesis.

Q99PF5	FUBP2_RAT	Far upstream element-binding protein 2	12358751	Molecular characterization of MARTA1, a protein interacting with the dendritic targeting element of MAP2 mRNAs.

Q9D1P0	RM13_MOUSE	39S ribosomal protein L13, mitochondrial	11279069	Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria.

P70412	CUZD1_MOUSE	CUB and zona pellucida-like domain-containing protein 1	9480914	A cDNA cloned from pregnant mouse uterus exhibits temporo-spatial expression and predicts a novel protein.

Q12366	NDJ1_YEAST	Non-disjunction protein 1	9242487	Tam1, a telomere-associated meiotic protein, functions in chromosome synapsis and crossover interference.

P15313	VATB1_HUMAN	V-type proton ATPase subunit B, kidney isoform	12414817	Novel ATP6V1B1 and ATP6V0A4 mutations in autosomal recessive distal renal tubular acidosis with new evidence for hearing loss.

O60235	TM11D_HUMAN	Transmembrane protease serine 11D	9565616	Cloning and characterization of the cDNA for human airway trypsin- like protease.

P30511	HLAF_HUMAN	HLA class I histocompatibility antigen, alpha chain F	1688605	Human leukocyte antigen F (HLA-F). An expressed HLA gene composed of a class I coding sequence linked to a novel transcribed repetitive element.

Q04347	BUD22_YEAST	Bud site selection protein 22	11452010	A genomic study of the bipolar bud site selection pattern in Saccharomyces cerevisiae.

O94285	RPC8_SCHPO	DNA-directed RNA polymerase III subunit rpc8	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q56YJ8	FAMA_ARATH	Transcription factor FAMA	17088607	Arabidopsis FAMA controls the final proliferation/differentiation switch during stomatal development.

Q9VXE5	PAKM_DROME	Serine/threonine-protein kinase PAK mbt	9811608	A protein related to p21-activated kinase (PAK) that is involved in neurogenesis in the Drosophila adult central nervous system.

Q6NLW5	XRI1_ARATH	Protein XRI1	19187040	A novel ATM dependant X-ray inducible gene is essential for both plant meiosis and gametogenesis.

Q554D9	SYNC_DICDI	Asparaginyl-tRNA synthetase, cytoplasmic	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q92624	APBP2_HUMAN	Amyloid protein-binding protein 2	11742091	The gamma -secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus.

Q9RX92	DDRA_DEIRA	Single-stranded DNA-binding protein DdrA	15454524	Analysis of Deinococcus radiodurans's transcriptional response to ionizing radiation and desiccation reveals novel proteins that contribute to extreme radioresistance.

Q9FHM4	MA653_ARATH	65-kDa microtubule-associated protein 3	18263774	MAP65-3 microtubule-associated protein is essential for nematode- induced giant cell ontogenesis in Arabidopsis.

P15927	RFA2_HUMAN	Replication protein A 32 kDa subunit	2406247	The primary structure of the 32-kDa subunit of human replication protein A.

P32450	AUA1_YEAST	Ammonia regulation of amino acid uptake protein	8497191	AUA1, a gene involved in ammonia regulation of amino acid transport in Saccharomyces cerevisiae.

P96614	CSHA_BACSU	DEAD-box ATP-dependent RNA helicase cshA	16861794	Bacillus subtilis DEAD protein YdbR possesses ATPase, RNA binding, and RNA unwinding activities.

Q965H3	SOP2_CAEEL	Polycomb protein sop-2	16501168	RNA-binding proteins SOP-2 and SOR-1 form a novel PcG-like complex in C. elegans.

Q56YU0	AL2C4_ARATH	Aldehyde dehydrogenase family 2 member C4	14729911	The Arabidopsis thaliana REDUCED EPIDERMAL FLUORESCENCE1 gene encodes an aldehyde dehydrogenase involved in ferulic acid and sinapic acid biosynthesis.

Q03769	ENT5_YEAST	Epsin-5	15107463	Ent5p is required with Ent3p and Vps27p for ubiquitin-dependent protein sorting into the multivesicular body.

Q01167	FOXK2_HUMAN	Forkhead box protein K2	16624804	Crystal structure of the human FOXK1a-DNA complex and its implications on the diverse binding specificity of winged helix/forkhead proteins.

P83628	IBP2_ONCTS	Insulin-like growth factor-binding protein 2	12765649	Purification of a 41-kDa insulin-like growth factor binding protein from serum of chinook salmon, Oncorhynchus tshawytscha.

Q8R1R5	C99L2_RAT	CD99 antigen-like protein 2	10834302	Molecular cloning of Rhombex-40 a transmembrane protein from the ventral medullary surface of the rat brain by differential display.

Q6UVK1	CSPG4_HUMAN	Chondroitin sulfate proteoglycan 4	10587647	Melanoma chondroitin sulphate proteoglycan regulates cell spreading through Cdc42, Ack-1 and p130cas.

P23693	TNNI3_RAT	Troponin I, cardiac muscle	1886137	Molecular cloning and developmental expression of the rat cardiac- specific isoform of troponin I.

Q9D2A5	CR3L4_MOUSE	Cyclic AMP-responsive element-binding protein 3-like protein 4	15938716	Tisp40, a spermatid specific bZip transcription factor, functions by binding to the unfolded protein response element via the Rip pathway.

Q9V3Z6	MYO7A_DROME	Myosin-VIIa	15579689	Drosophila crinkled, mutations of which disrupt morphogenesis and cause lethality, encodes fly myosin VIIA.

P42777	GBF4_ARATH	G-box-binding factor 4	8146148	Isolation and characterization of a fourth Arabidopsis thaliana G- box-binding factor, which has similarities to Fos oncoprotein.

P42834	MDJ2_YEAST	Mitochondrial DnaJ homolog 2	9325105	Mdj2p, a novel DnaJ homolog in the mitochondrial inner membrane of the yeast Saccharomyces cerevisiae.

Q9BYC8	RM32_HUMAN	39S ribosomal protein L32, mitochondrial	11543634	The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders.

P0CAZ1	TTL3F_TETTH	Tubulin glycylase 3F	19531357	TTLL3 Is a tubulin glycine ligase that regulates the assembly of cilia.

Q2XPP5	ATG8A_ORYSI	Autophagy-related protein 8A	17082902	Identification and characterization of two rice autophagy associated genes, OsAtg8 and OsAtg4.

Q09199	B4GN2_MOUSE	Beta-1,4 N-acetylgalactosaminyltransferase 2	7515051	Molecular cloning of a murine N-acetylgalactosamine transferase cDNA that determines expression of the T lymphocyte-specific CT oligosaccharide differentiation antigen.

Q06520	ST2A1_HUMAN	Bile salt sulfotransferase	1588921	Human liver dehydroepiandrosterone sulfotransferase: molecular cloning and expression of cDNA.

P82669	RT25_BOVIN	28S ribosomal protein S25, mitochondrial	10938081	A proteomics approach to the identification of mammalian mitochondrial small subunit ribosomal proteins.

P82997	GSTE_PSEUF	Glutathione S-transferase	11900268	Occurence and properties of glutathione S-transferases in phenol- degrading Pseudomonas strains.

P63005	LIS1_MOUSE	Platelet-activating factor acetylhydrolase IB subunit alpha	14691133	A role for cytoplasmic dynein and LIS1 in directed cell movement.

Q9NVJ2	ARL8B_HUMAN	ADP-ribosylation factor-like protein 8B	15331635	Novel small GTPase subfamily capable of associating with tubulin is required for chromosome segregation.

O82175	SUVH5_ARATH	Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH5	11691919	The Arabidopsis thaliana genome contains at least 29 active genes encoding SET domain proteins that can be assigned to four evolutionarily conserved classes.

Q9UQ80	PA2G4_HUMAN	Proliferation-associated protein 2G4	15583694	Specificity and heregulin regulation of Ebp1 (ErbB3 binding protein 1) mediated repression of androgen receptor signalling.

P55268	LAMB2_HUMAN	Laminin subunit beta-2	7698745	Human beta 2 chain of laminin (formerly S chain): cDNA cloning, chromosomal localization, and expression in carcinomas.

Q09892	HOG1_SCHPO	Mitogen-activated protein kinase sty1	9251044	Stress-activated protein kinase pathway in cell cycle control of fission yeast.

P01365	MTAL1_YEAST	Mating-type protein ALPHA1	8339934	Coupling of cell identity to signal response in yeast: interaction between the alpha-1 and STE12 proteins.

Q92258	GRISA_PODAN	Protein GRISEA	9894921	GRISEA, a copper-modulated transcription factor from Podospora anserina involved in senescence and morphogenesis, is an ortholog of MAC1 in Saccharomyces cerevisiae.

Q9LKI5	XPF_ARATH	DNA repair endonuclease UVH1	12393748	Role of the AtRad1p endonuclease in homologous recombination in plants.

P24100	CDKA1_ARATH	Cyclin-dependent kinase A-1	16460514	Arabidopsis CDKA;1, a cdc2 homologue, controls proliferation of generative cells in male gametogenesis.

Q9LSQ4	GH36_ARATH	Indole-3-acetic acid-amido synthetase GH3.6	15659623	Characterization of an Arabidopsis enzyme family that conjugates amino acids to indole-3-acetic acid.

Q6DT37	MRCKG_HUMAN	Serine/threonine-protein kinase MRCK gamma	9341881	The germinal centre kinase gene and a novel CDC25-like gene are located in the vicinity of the PYGM gene on 11q13.

P92973	CCA1_ARATH	Protein CCA1	19218364	CIRCADIAN CLOCK ASSOCIATED1 and LATE ELONGATED HYPOCOTYL function synergistically in the circadian clock of Arabidopsis.

Q9UH99	SUN2_HUMAN	SUN domain-containing protein 2	18396275	Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness.

Q06685	VIP1_YEAST	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase	14562095	Global analysis of protein localization in budding yeast.

Q76EJ0	YABDL_ORYSJ	Protein DROOPING LEAF	14729915	The YABBY gene DROOPING LEAF regulates carpel specification and midrib development in Oryza sativa.

Q08170	SRSF4_HUMAN	Serine/arginine-rich splicing factor 4	8321209	Human SR proteins and isolation of a cDNA encoding SRp75.

Q9BSJ2	GCP2_HUMAN	Gamma-tubulin complex component 2	9566967	The mammalian gamma-tubulin complex contains homologues of the yeast spindle pole body components spc97p and spc98p.

Q9GZN0	GPR88_HUMAN	Probable G-protein coupled receptor 88	11056049	A novel G-protein-coupled receptor gene expressed in striatum.

Q02206	RSC4_YEAST	Chromatin structure-remodeling complex subunit RSC4	10025404	Histone octamer transfer by a chromatin-remodeling complex.

P31749	AKT1_HUMAN	RAC-alpha serine/threonine-protein kinase	14749367	Regulation of apoptosis by the Ft1 protein, a new modulator of protein kinase B/Akt.

P42124	EZ_DROME	Histone-lysine N-methyltransferase E(z)	12408863	Drosophila Enhancer of zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites.

Q7Z2E3	APTX_HUMAN	Aprataxin	16777843	Nucleolar localization of aprataxin is dependent on interaction with nucleolin and on active ribosomal DNA transcription.

Q9QUL0	PR3C1_RAT	Prolactin-3C1	10471365	Identification of four members of the rat prolactin/growth hormone gene family.

P38219	OLA1_YEAST	Uncharacterized GTP-binding protein OLA1	10684247	The yeast nuclear pore complex: composition, architecture, and transport mechanism.

P84509	TX3_CERMR	Beta-theraphotoxin-Cm2a	16267209	Four novel tarantula toxins as selective modulators of voltage-gated sodium channel subtypes.

Q03264	NGL2_YEAST	RNA exonuclease NGL2	12358428	Ngl2p is a Ccr4p-like RNA nuclease essential for the final step in 3'-end processing of 5.8S rRNA in Saccharomyces cerevisiae.

P51636	CAV2_HUMAN	Caveolin-2	18081315	Serine 23 and 36 phosphorylation of caveolin-2 is differentially regulated by targeting to lipid raft/caveolae and in mitotic endothelial cells.

O04017	NAC98_ARATH	Protein CUP-SHAPED COTYLEDON 2	17251269	Plants expressing a miR164-resistant CUC2 gene reveal the importance of post-meristematic maintenance of phyllotaxy in Arabidopsis.

Q93038	TNR25_HUMAN	Tumor necrosis factor receptor superfamily member 25	9052839	TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas(Apo-1/CD95).

P70196	TRAF6_MOUSE	TNF receptor-associated factor 6	10421844	Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient mice.

P47914	RL29_HUMAN	60S ribosomal protein L29	8597591	A novel cDNA encoding a human homologue of ribosomal protein L29.

P46597	HIOM_HUMAN	Hydroxyindole O-methyltransferase	8397829	Human hydroxyindole-O-methyltransferase: presence of LINE-1 fragment in a cDNA clone and pineal mRNA.

O94327	TSPO_SCHPO	Translocator protein homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q08955	CSM4_YEAST	Chromosome segregation in meiosis protein 4	11470404	A screen for genes required for meiosis and spore formation based on whole-genome expression.

Q9WTQ6	TRIB3_RAT	Tribbles homolog 3	10329375	Identification of a novel kinase-like gene induced during neuronal cell death.

P54645	AAPK1_RAT	5'-AMP-activated protein kinase catalytic subunit alpha-1	14511394	Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade.

Q6LD29	FXA1A_XENLA	Forkhead box protein A1-A	15656969	Of fox and frogs: fox (fork head/winged helix) transcription factors in Xenopus development.

P40452	COA1_YEAST	Cytochrome oxidase assembly protein 1	17882260	Coa1 links the Mss51 post-translational function to Cox1 cofactor insertion in cytochrome c oxidase assembly.

P39081	PCF11_YEAST	Protein PCF11	12727883	Independent functions of yeast Pcf11p in pre-mRNA 3' end processing and in transcription termination.

P0AA89	DOSC_ECOLI	Diguanylate cyclase DosC	19764732	An oxygen-sensing diguanylate cyclase and phosphodiesterase couple for c-di-GMP control.

Q13224	NMDE2_HUMAN	Glutamate [NMDA] receptor subunit epsilon-2	8768735	Cloning and functional characterization of human heteromeric N- methyl-D-aspartate receptors.

Q00493	CBPE_MOUSE	Carboxypeptidase E	7663508	Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity.

Q86BE9	PEN2_DROME	Gamma-secretase subunit pen-2	12660785	The role of presenilin cofactors in the gamma-secretase complex.

Q9UT88	ERG8_SCHPO	Probable phosphomevalonate kinase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P01346	IGF2_RAT	Insulin-like growth factor II	3023383	Structure and expression of the rat insulin-like growth factor II (rIGF-II) gene. rIGF-II RNAs are transcribed from two promoters.

P47075	VTC4_YEAST	Vacuolar transporter chaperone 4	12584253	Role of the Vtc proteins in V-ATPase stability and membrane trafficking.

Q09811	HUS2_SCHPO	ATP-dependent DNA helicase hus2/rqh1	9184215	rqh1+, a fission yeast gene related to the Bloom's and Werner's syndrome genes, is required for reversible S phase arrest.

Q9NR30	DDX21_HUMAN	Nucleolar RNA helicase 2	8614622	A nucleolar RNA helicase recognized by autoimmune antibodies from a patient with watermelon stomach disease.

P47858	K6PF_RAT	6-phosphofructokinase, muscle type	8764833	Characterization of expression of phosphofructokinase isoforms in isolated rat pancreatic islets and purified beta cells and cloning and expression of the rat phosphofructokinase-A isoform.

P53083	MDM34_YEAST	Mitochondrial distribution and morphology protein 34	14562095	Global analysis of protein localization in budding yeast.

P43688	NKX26_MOUSE	Homeobox protein Nkx-2.6	9486544	Nkx2.6 expression is transiently and specifically restricted to the branchial region of pharyngeal-stage mouse embryos.

O70173	P3C2G_RAT	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma	9516481	A novel class II phosphoinositide 3-kinase predominantly expressed in the liver and its enhanced expression during liver regeneration.

P41161	ETV5_HUMAN	ETS translocation variant 5	8152800	Molecular cloning and characterization of human ERM, a new member of the Ets family closely related to mouse PEA3 and ER81 transcription factors.

Q05901	ACHB3_HUMAN	Neuronal acetylcholine receptor subunit beta-3	8906617	Comparative structure of human neuronal alpha 2-alpha 7 and beta 2- beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits.

O95487	SC24B_HUMAN	Protein transport protein Sec24B	10075675	Sec24 proteins and sorting at the endoplasmic reticulum.

Q91898	HESXB_XENLA	Homeobox expressed in ES cells 1-B	10498686	The homeobox gene, Xanf-1, can control both neural differentiation and patterning in the presumptive anterior neurectoderm of the Xenopus laevis embryo.

P47166	SGM1_YEAST	Protein SGM1	14562095	Global analysis of protein localization in budding yeast.

Q13627	DYR1A_HUMAN	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	14500717	Serine/threonine kinase Mirk/Dyrk1B is an inhibitor of epithelial cell migration and is negatively regulated by the Met adaptor Ran- binding protein M.

P06687	AT1A3_RAT	Sodium/potassium-transporting ATPase subunit alpha-3	2822726	Three differentially expressed Na,K-ATPase alpha subunit isoforms: structural and functional implications.

Q15181	IPYR_HUMAN	Inorganic pyrophosphatase	10542310	Cloning and expression profile of human inorganic pyrophosphatase.

Q06337	EAF1_YEAST	Chromatin modification-related protein EAF1	15045029	A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin.

P07668	CLAT_DROME	Choline O-acetyltransferase	2723644	Sequence analysis of a proteolyzed site in Drosophila choline acetyltransferase.

Q13257	MD2L1_HUMAN	Mitotic spindle assembly checkpoint protein MAD2A	18022368	p31comet blocks Mad2 activation through structural mimicry.

O93614	GDS1A_XENLA	Rap1 GTPase-GDP dissociation stimulator 1-A	9753634	Identification and characterization in Xenopus of XsmgGDS, a RalB- binding protein.

P38806	YNG2_YEAST	Chromatin modification-related protein YNG2	10805724	Three yeast proteins related to the human candidate tumor suppressor p33(ING1) are associated with histone acetyltransferase activities.

Q13185	CBX3_HUMAN	Chromobox protein homolog 3	15502821	A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1.

Q8N2H9	PELI3_HUMAN	Protein pellino homolog 3	12874243	Pellino3, a novel member of the Pellino protein family, promotes activation of c-Jun and Elk-1 and may act as a scaffolding protein.

P35428	HES1_MOUSE	Transcription factor HES-1	10851137	The bHLH gene Hes6, an inhibitor of Hes1, promotes neuronal differentiation.

Q8K4G5	ABLM1_MOUSE	Actin-binding LIM protein 1	11163266	A POU domain transcription factor-dependent program regulates axon pathfinding in the vertebrate visual system.

P34120	PSA7_DICDI	Proteasome subunit alpha type-7	8130037	Proteasomes from Dictyostelium discoideum: characterization of structure and function.

Q9QZM2	DPOG2_MOUSE	DNA polymerase subunit gamma-2, mitochondrial	10666468	Protein sequences conserved in prokaryotic aminoacyl-tRNA synthetases are important for the activity of the processivity factor of human mitochondrial DNA polymerase.

Q12171	MDM32_YEAST	Mitochondrial distribution and morphology protein 32	14562095	Global analysis of protein localization in budding yeast.

P53541	SPO1_YEAST	Putative meiotic phospholipase SPO1	17179081	Genetic evidence for a SPO1-dependent signaling pathway controlling meiotic progression in yeast.

Q9UTD5	YID4_SCHPO	Uncharacterized protein C227.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P30305	MPIP2_HUMAN	M-phase inducer phosphatase 2	1836978	Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: evidence for multiple roles of mitotic cyclins.

P80042	GGPPS_CAPAN	Geranylgeranyl pyrophosphate synthase, chloroplastic	1303794	Identification of a cDNA for the plastid-located geranylgeranyl pyrophosphate synthase from Capsicum annuum: correlative increase in enzyme activity and transcript level during fruit ripening.

P07668	CLAT_DROME	Choline O-acetyltransferase	1851526	The amino terminus of the putative Drosophila choline acetyltransferase precursor is cleaved to yield the 67 kDa enzyme.

O13685	UBC13_SCHPO	Ubiquitin-conjugating enzyme E2 13	12531016	Structural and functional conservation of error-free DNA postreplication repair in Schizosaccharomyces pombe.

O15379	HDAC3_HUMAN	Histone deacetylase 3	9501169	Characterization of a human RPD3 ortholog, HDAC3.

P40517	YRB2_YEAST	Ran-specific GTPase-activating protein 2	9395535	Yrb2p is a nuclear protein that interacts with Prp20p, a yeast Rcc1 homologue.

O76041	NEBL_HUMAN	Nebulette	9733644	Characterization of nebulette and nebulin and emerging concepts of their roles for vertebrate Z-discs.

Q00869	ESYN_FUSEQ	Enniatin synthase	7601090	Arrangement of catalytic sites in the multifunctional enzyme enniatin synthetase.

P0CC16	OXLA_AGKCL	L-amino-acid oxidase	10441379	Isolation and structural characterization of a cytotoxic L-amino acid oxidase from Agkistrodon contortrix laticinctus snake venom: preliminary crystallographic data.

Q9FVJ3	AGD12_ARATH	ADP-ribosylation factor GTPase-activating protein AGD12	11202441	Promiscuous and specific phospholipid binding by domains in ZAC, a membrane-associated Arabidopsis protein with an ARF GAP zinc finger and a C2 domain.

P0C7Q8	DA1_ARATH	Protein DA1	18483219	Control of final seed and organ size by the DA1 gene family in Arabidopsis thaliana.

Q94AG2	SERK1_ARATH	Somatic embryogenesis receptor kinase 1	16621602	The Arabidopsis thaliana AAA protein CDC48A interacts in vivo with the somatic embryogenesis receptor-like kinase 1 receptor at the plasma membrane.

P0C0T5	MEPA_ECOLI	Penicillin-insensitive murein endopeptidase	2187143	Cloning and characterization of mepA, the structural gene of the penicillin-insensitive murein endopeptidase from Escherichia coli.

Q12163	NBP2_YEAST	NAP1-binding protein 2	14573466	Yeast Nap1-binding protein Nbp2p is required for mitotic growth at high temperatures and for cell wall integrity.

Q5BAP5	EGLX_EMENI	Endo-1,3(4)-beta-glucanase xgeA	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

O95758	ROD1_HUMAN	Regulator of differentiation 1	10207106	Isolation of a mammalian homologue of a fission yeast differentiation regulator.

Q60997	DMBT1_MOUSE	Deleted in malignant brain tumors 1 protein	15292166	Binding of the Golgi sorting receptor muclin to pancreatic zymogens through sulfated O-linked oligosaccharides.

P19018	TRA2_DROME	Transformer-2 sex-determining protein	1674449	Sex-specific splicing and polyadenylation of dsx pre-mRNA requires a sequence that binds specifically to tra-2 protein in vitro.

O75815	BCAR3_HUMAN	Breast cancer anti-estrogen resistance protein 3	9582273	Identification of BCAR3 by a random search for genes involved in antiestrogen resistance of human breast cancer cells.

P18486	L2AM_DROME	Alpha-methyldopa hypersensitive protein	3021571	Molecular localization, developmental expression and nucleotide sequence of the alpha-methyldopa hypersensitive gene of Drosophila.

P91938	TRXR1_DROME	Thioredoxin reductase 1, mitochondrial	11796729	Mitochondrial and cytoplasmic thioredoxin reductase variants encoded by a single Drosophila gene are both essential for viability.

Q03373	DIG2_YEAST	Down-regulator of invasive growth 2	10825185	Two regulators of Ste12p inhibit pheromone-responsive transcription by separate mechanisms.

O88974	SETB1_MOUSE	Histone-lysine N-methyltransferase SETDB1	11791185	Molecular cloning of ESET, a novel histone H3-specific methyltransferase that interacts with ERG transcription factor.

Q9SU30	CPR30_ARATH	F-box protein CPR30	19682297	An F-box gene, CPR30, functions as a negative regulator of the defense response in Arabidopsis.

P14604	ECHM_RAT	Enoyl-CoA hydratase, mitochondrial	2806264	Molecular cloning and sequence analysis of the cDNA for rat mitochondrial enoyl-CoA hydratase. Structural and evolutionary relationships linked to the bifunctional enzyme of the peroxisomal beta-oxidation system.

Q63572	TESK1_RAT	Dual specificity testis-specific protein kinase 1	8537404	Identification and characterization of a novel protein kinase, TESK1, specifically expressed in testicular germ cells.

P33416	HSP78_YEAST	Heat shock protein 78, mitochondrial	16460754	The disaggregation activity of the mitochondrial ClpB homolog Hsp78 maintains Hsp70 function during heat stress.

Q00764	TPS1_YEAST	Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit	1425702	Characterization of the 56-kDa subunit of yeast trehalose-6-phosphate synthase and cloning of its gene reveal its identity with the product of CIF1, a regulator of carbon catabolite inactivation.

P84693	SC66_TITCA	Toxin Tc66	15025998	Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

O55134	PCD12_MOUSE	Protocadherin-12	9651350	Identification of a novel cadherin (vascular endothelial cadherin-2) located at intercellular junctions in endothelial cells.

P80667	PEX13_YEAST	Peroxisomal membrane protein PAS20	8858166	The SH3 domain of the Saccharomyces cerevisiae peroxisomal membrane protein Pex13p functions as a docking site for Pex5p, a mobile receptor for the import PTS1-containing proteins.

Q8UWF0	SC5A7_TORMA	High-affinity choline transporter 1	12358793	The neuronal choline transporter CHT1 is regulated by immunosuppressor-sensitive pathways.

Q9Y169	EXT2_DROME	Exostosin-2	14645127	Three Drosophila EXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans.

P83139	AFP5_MALPA	Antifungal protein 5	11302747	Purification and characterization of three antifungal proteins from cheeseweed (Malva parviflora).

Q9US45	MED6_SCHPO	Mediator of RNA polymerase II transcription subunit 6	10625684	Purification and characterization of RNA polymerase II holoenzyme from Schizosaccharomyces pombe.

Q98SK0	MDFIC_XENLA	MyoD family inhibitor domain-containing protein	15923623	XIC is required for Siamois activity and dorsoanterior development.

P35749	MYH11_HUMAN	Myosin-11	7684189	Human smooth muscle myosin heavy chain gene mapped to chromosomal region 16q12.

Q9Y2T3	GUAD_HUMAN	Guanine deaminase	10542258	A novel NE-dlg/SAP102-associated protein, p51-nedasin, related to the amidohydrolase superfamily, interferes with the association between NE-dlg/SAP102 and N-methyl-D-aspartate receptor.

O43031	SPP2_SCHPO	Pre-mRNA-splicing factor spp2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O01427	AIR2_CAEEL	Aurora/IPL1-related protein kinase 2	10983970	The survivin-like C. elegans BIR-1 protein acts with the Aurora-like kinase AIR-2 to affect chromosomes and the spindle midzone.

P34118	MVPA_DICDI	Major vault protein alpha	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

Q8TDC0	MYOZ3_HUMAN	Myozenin-3	11842093	Calsarcin-3, a novel skeletal muscle-specific member of the calsarcin family, interacts with multiple Z-disc proteins.

P20783	NTF3_HUMAN	Neurotrophin-3	2236018	Molecular cloning of a human gene that is a member of the nerve growth factor family.

P28274	URA7_YEAST	CTP synthase 1	1753946	Cloning, sequencing and characterization of the Saccharomyces cerevisiae URA7 gene encoding CTP synthetase.

P25655	NOT1_YEAST	General negative regulator of transcription subunit 1	11733989	Purification and characterization of the 1.0 MDa CCR4-NOT complex identifies two novel components of the complex.

Q9D1N2	HDBP1_MOUSE	Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1	12496272	Expression cloning and characterization of a novel glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein, GPI-HBP1.

O88806	PADI1_RAT	Protein-arginine deiminase type-1	9738944	Molecular cloning of two novel types of peptidylarginine deiminase cDNAs from retinoic acid-treated culture of a newborn rat keratinocyte cell line.

Q99767	APBA2_HUMAN	Amyloid beta A4 precursor protein-binding family A member 2	10833507	Regulation of X11L-dependent amyloid precursor protein metabolism by XB51, a novel X11L-binding protein.

O42781	MAPK2_PNECA	Mitogen-activated protein kinase 2	12965219	Complementation and characterization of the Pneumocystis carinii MAPK, PCM.

O75888	TNF13_HUMAN	Tumor necrosis factor ligand superfamily member 13	9743536	APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth.

Q06511	RRP15_YEAST	Ribosomal RNA-processing protein 15	15769876	Rrp15p, a novel component of pre-ribosomal particles required for 60S ribosome subunit maturation.

Q14055	CO9A2_HUMAN	Collagen alpha-2(IX) chain	10364514	Identification of novel pro-alpha2(IX) collagen gene mutations in two families with distinctive oligo-epiphyseal forms of multiple epiphyseal dysplasia.

Q07916	PO6F1_MOUSE	POU domain, class 6, transcription factor 1	8463278	A novel class of murine POU gene predominantly expressed in central nervous system.

Q02792	XRN2_YEAST	5'-3' exoribonuclease 2	15565157	The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II.

Q920M7	SYT17_MOUSE	Synaptotagmin-17	11716773	The N-terminal cysteine cluster is essential for membrane targeting of B/K protein.

P54253	ATX1_HUMAN	Ataxin-1	9097953	Identification of a self-association region within the SCA1 gene product, ataxin-1.

Q15019	SEPT2_HUMAN	Septin-2	17803907	Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7.

P51003	PAPOA_HUMAN	Poly(A) polymerase alpha	8302877	Multiple forms of poly(A) polymerases in human cells.

P63006	LHX1_MOUSE	LIM/homeobox protein Lhx1	9468533	Interactions between LIM domains and the LIM domain-binding protein Ldb1.

Q01107	DSC1_BOVIN	Desmocollin-1	2277091	Desmosomal glycoproteins 2 and 3 (desmocollins) show N-terminal similarity to calcium-dependent cell-cell adhesion molecules.

Q9Y625	GPC6_HUMAN	Glypican-6	10329016	GPC6, a novel member of the glypican gene family, encodes a product structurally related to GPC4 and is colocalized with GPC5 on human chromosome 13.

Q9U0M8	YPF06_PLAF7	Uncharacterized protein PFA0635c	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

O15350	P73_HUMAN	Tumor protein p73	19581926	The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73.

Q9HDU7	YHE8_SCHPO	UPF0643 protein PB2B2.08	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12309	CLF1_YEAST	Pre-mRNA-splicing factor CLF1	11973290	Evidence that the pre-mRNA splicing factor Clf1p plays a role in DNA replication in Saccharomyces cerevisiae.

O16011	MBL_DROME	Protein muscleblind	9334280	Muscleblind, a gene required for photoreceptor differentiation in Drosophila, encodes novel nuclear Cys3His-type zinc-finger-containing proteins.

Q19469	SAD1_CAEEL	Serine/threonine kinase SAD-1	20023164	C. elegans STRADalpha and SAD cooperatively regulate neuronal polarity and synaptic organization.

O14000	SYMM_SCHPO	Probable methionyl-tRNA synthetase, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Y5P3	RAI2_HUMAN	Retinoic acid-induced protein 2	10049581	Identification and characterization of the human homologue (RAI2) of a mouse retinoic acid-induced gene in Xp22.

Q16719	KYNU_HUMAN	Kynureninase	17334708	Xanthurenic aciduria due to a mutation in KYNU encoding kynureninase.

Q8GYN5	RIN4_ARATH	RPM1-interacting protein 4	15845764	The Pseudomonas syringae effector AvrRpt2 cleaves its C-terminally acylated target, RIN4, from Arabidopsis membranes to block RPM1 activation.

Q02774	SHR3_YEAST	Secretory component protein SHR3	1423607	SHR3: a novel component of the secretory pathway specifically required for localization of amino acid permeases in yeast.

P0AFA7	NHAB_ECOLI	Na(+)/H(+) antiporter nhaB	1317851	Cloning, sequencing, and expression of the nhaB gene, encoding a Na+/H+ antiporter in Escherichia coli.

Q8IYM9	TRI22_HUMAN	E3 ubiquitin-protein ligase TRIM22	7797467	Molecular cloning of a new interferon-induced factor that represses human immunodeficiency virus type 1 long terminal repeat expression.

P53309	AP18B_YEAST	Clathrin coat assembly protein AP180B	9531549	Pan1p, yeast eps15, functions as a multivalent adaptor that coordinates protein-protein interactions essential for endocytosis.

Q9UP95	S12A4_HUMAN	Solute carrier family 12 member 4	9516379	Molecular identification and expression of erythroid K:Cl cotransporter in human and mouse erythroleukemic cells.

P21461	SINA_DROME	E3 ubiquitin-protein ligase sina	12215542	Phyllopod acts as an adaptor protein to link the sina ubiquitin ligase to the substrate protein tramtrack.

P42949	TIM16_YEAST	Mitochondrial import inner membrane translocase subunit TIM16	14981506	The J domain-related cochaperone Tim16 is a constituent of the mitochondrial TIM23 preprotein translocase.

Q09013	DMPK_HUMAN	Myotonin-protein kinase	1310900	Molecular basis of myotonic dystrophy: expansion of a trinucleotide (CTG) repeat at the 3' end of a transcript encoding a protein kinase family member.

O42662	YF88_SCHPO	Putative methyltransferase C27D7.08c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O74971	ATG5_SCHPO	Autophagy protein 5	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q15654	TRIP6_HUMAN	Thyroid receptor-interacting protein 6	9598321	The human TRIP6 gene encodes a LIM domain protein and maps to chromosome 7q22, a region associated with tumorigenesis.

Q9JMI9	TRPC3_RAT	Short transient receptor potential channel 3	10984475	A calcium-activated cation current by an alternatively spliced form of Trp3 in the heart.

P47069	MPS3_YEAST	Spindle pole body assembly component MPS3	17245108	The nuclear envelope and spindle pole body-associated Mps3 protein bind telomere regulators and function in telomere clustering.

O00339	MATN2_HUMAN	Matrilin-2	11124542	Primary structure of human matrilin-2, chromosome location of the MATN2 gene and conservation of an AT-AC intron in matrilin genes.

Q15435	PP1R7_HUMAN	Protein phosphatase 1 regulatory subunit 7	10231361	Structure and splice products of the human gene encoding sds22, a putative mitotic regulator of protein phosphatase-1.

Q92797	SYMPK_HUMAN	Symplekin	8769423	Symplekin, a novel type of tight junction plaque protein.

P45819	SPO74_YEAST	Sporulation-specific protein 74	12796288	Ady4p and Spo74p are components of the meiotic spindle pole body that promote growth of the prospore membrane in Saccharomyces cerevisiae.

O00299	CLIC1_HUMAN	Chloride intracellular channel protein 1	12163479	AKAP350 at the Golgi apparatus. II. Association of AKAP350 with a novel chloride intracellular channel (CLIC) family member.

Q3U1F9	PAG1_MOUSE	Phosphoprotein associated with glycosphingolipid-enriched microdomains 1	12612075	Phosphorylation-dependent regulation of T-cell activation by PAG/Cbp, a lipid raft-associated transmembrane adaptor.

O75298	RTN2_HUMAN	Reticulon-2	9693037	cDNA cloning, genomic organization, and expression of the human RTN2 gene, a member of a gene family encoding reticulons.

Q61143	TRPC6_MOUSE	Short transient receptor potential channel 6	9368034	Cloning and expression of a novel mammalian homolog of Drosophila transient receptor potential (Trp) involved in calcium entry secondary to activation of receptors coupled by the Gq class of G protein.

Q9CQ26	STABP_MOUSE	STAM-binding protein	11713295	Loss of neurons in the hippocampus and cerebral cortex of AMSH- deficient mice.

Q84TU6	PETD_EUGGR	Cytochrome b6-f complex subunit 4, chloroplastic	12837550	Cytochrome f and subunit IV, two essential components of the photosynthetic bf complex typically encoded in the chloroplast genome, are nucleus-encoded in Euglena gracilis.

P12036	NFH_HUMAN	Neurofilament heavy polypeptide	3138108	The structure and organization of the human heavy neurofilament subunit (NF-H) and the gene encoding it.

P43630	KI3L2_HUMAN	Killer cell immunoglobulin-like receptor 3DL2	7716543	Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells.

Q9SCT4	IMK2_ARATH	Probably inactive leucine-rich repeat receptor-like protein kinase IMK2	16618929	Mapping the Arabidopsis organelle proteome.

P36116	VPS51_YEAST	Vacuolar protein sorting-associated protein 51	12377769	Vps51p links the VFT complex to the SNARE Tlg1p.

Q04377	LCD1_YEAST	DNA damage checkpoint protein LCD1	12181334	MEC3, MEC1, and DDC2 are essential components of a telomere checkpoint pathway required for cell cycle arrest during senescence in Saccharomyces cerevisiae.

Q7Z9I2	YCP9_SCHPO	Uncharacterized oxidoreductase C663.09c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q18434	GPA17_CAEEL	Guanine nucleotide-binding protein alpha-17 subunit	15342507	A network of stimulatory and inhibitory Galpha-subunits regulates olfaction in Caenorhabditis elegans.

Q9XIP7	GTG1_ARATH	GPCR-type G protein 1	19135895	Two novel GPCR-type G proteins are abscisic acid receptors in Arabidopsis.

Q9ZVR7	PSKR1_ARATH	Phytosulfokine receptor 1	17989228	Tyrosine-sulfated glycopeptide involved in cellular proliferation and expansion in Arabidopsis.

Q9D1F4	AKTS1_MOUSE	Proline-rich AKT1 substrate 1	16397181	Modulation of proline-rich akt substrate survival signaling pathways by oxidative stress in mouse brains after transient focal cerebral ischemia.

Q9SWH5	FUT1_ARATH	Galactoside 2-alpha-L-fucosyltransferase	10373113	Xyloglucan fucosyltransferase, an enzyme involved in plant cell wall biosynthesis.

Q9JLB9	PVRL3_MOUSE	Poliovirus receptor-related protein 3	12826663	Implications of nectin-like molecule- 2/IGSF4/RA175/SgIGSF/TSLC1/SynCAM1 in cell-cell adhesion and transmembrane protein localization in epithelial cells.

Q388M1	GSK3B_TRYBB	Glycogen synthase kinase 3	18644955	Glycogen synthase kinase 3 is a potential drug target for African trypanosomiasis therapy.

P57790	KEAP1_RAT	Kelch-like ECH-associated protein 1	11439354	Functional characterization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene.

Q9Y4K3	TRAF6_HUMAN	TNF receptor-associated factor 6	20079715	NUMBL interacts with TRAF6 and promotes the degradation of TRAF6.

Q12514	NOT5_YEAST	General negative regulator of transcription subunit 5	10490603	The CCR4 and CAF1 proteins of the CCR4-NOT complex are physically and functionally separated from NOT2, NOT4, and NOT5.

Q6BAA4	FCRLB_HUMAN	Fc receptor-like B	15815692	A new Fc receptor homolog, FREB2, found in germinal center B cells.

Q9SLH3	RGA_ARATH	DELLA protein RGA	9490740	The Arabidopsis RGA gene encodes a transcriptional regulator repressing the gibberellin signal transduction pathway.

P56206	SYG_THET8	Glycyl-tRNA synthetase	7556056	Crystal structure of glycyl-tRNA synthetase from Thermus thermophilus.

Q92341	STR3_SCHPO	Siderophore iron transporter 3	12888492	Fep1 represses expression of the fission yeast Schizosaccharomyces pombe siderophore-iron transport system.

A2ALU4	SHRM2_MOUSE	Protein Shroom2	16987870	Shroom2 (APXL) regulates melanosome biogenesis and localization in the retinal pigment epithelium.

P26358	DNMT1_HUMAN	DNA (cytosine-5)-methyltransferase 1	18413740	DNA methyltransferase 1 and 3B activate BAG-1 expression via recruitment of CTCFL/BORIS and modulation of promoter histone methylation.

Q9FUY2	LEUNG_ARATH	Transcriptional corepressor LEUNIG	7743940	LEUNIG regulates AGAMOUS expression in Arabidopsis flowers.

P08425	SYFM_YEAST	Phenylalanyl-tRNA synthetase, mitochondrial	3029120	Isolation and characterization of the yeast gene coding for the alpha subunit of mitochondrial phenylalanyl-tRNA synthetase.

Q8NFH8	REPS2_HUMAN	RalBP1-associated Eps domain-containing protein 2	9928989	Solution structure of the Eps15 homology domain of a human POB1 (partner of RalBP1).

P08010	GSTM2_RAT	Glutathione S-transferase Mu 2	3020050	Rat glutathione S-transferases supergene family. Characterization of an anionic Yb subunit cDNA clone.

Q96RS0	TGS1_HUMAN	Trimethylguanosine synthase	16687569	Ongoing U snRNP biogenesis is required for the integrity of Cajal bodies.

O00214	LEG8_HUMAN	Galectin-8	8692978	Surface-epitope masking and expression cloning identifies the human prostate carcinoma tumor antigen gene PCTA-1 a member of the galectin gene family.

Q9TW65	DMD_CAEEL	Dystrophin-1	10561496	In vitro interactions of Caenorhabditis elegans dystrophin with dystrobrevin and syntrophin.

P76169	YNFA_ECOLI	UPF0060 membrane protein ynfA	11867724	Rapid topology mapping of Escherichia coli inner-membrane proteins by prediction and PhoA/GFP fusion analysis.

Q8IWY4	SCUB1_HUMAN	Signal peptide, CUB and EGF-like domain-containing protein 1	12270931	Identification of a novel family of cell-surface proteins expressed in human vascular endothelium.

O42342	SOX7_XENLA	Transcription factor Sox-7	16193513	SOX7 and SOX18 are essential for cardiogenesis in Xenopus.

Q9UUH2	YKIA_SCHPO	UPF0657 nucleolar protein C630.10	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P69776	LPP_ECOLI	Major outer membrane lipoprotein Lpp	4575979	Covalent binding of lipid to protein. Diglyceride and amide-linked fatty acid at the N-terminal end of the murein-lipoprotein of the Escherichia coli outer membrane.

O13282	TAF5_SCHPO	Transcription initiation factor TFIID subunit 5	11279037	Two WD repeat-containing TATA-binding protein-associated factors in fission yeast that suppress defects in the anaphase-promoting complex.

Q8R553	CSTN3_RAT	Calsyntenin-3	12498782	The calsyntenins - a family of postsynaptic membrane proteins with distinct neuronal expression patterns.

Q9NS86	LANC2_HUMAN	LanC-like protein 2	19667068	LANCL2 is necessary for abscisic acid binding and signaling in human granulocytes and in rat insulinoma cells.

Q6R005	DLG4_DANRE	Disks large homolog 4	15660367	Characterization of zebrafish PSD-95 gene family members.

O60938	KERA_HUMAN	Keratocan	10802664	Mutations in KERA, encoding keratocan, cause cornea plana.

P34896	GLYC_HUMAN	Serine hydroxymethyltransferase, cytosolic	8505317	Cloning of human cDNAs encoding mitochondrial and cytosolic serine hydroxymethyltransferases and chromosomal localization.

Q91876	MCM7A_XENLA	DNA replication licensing factor mcm7-A	9214646	The RLF-M component of the replication licensing system forms complexes containing all six MCM/P1 polypeptides.

P20052	PHO80_YEAST	PHO85 cyclin PHO80	16455487	Mapping pathways and phenotypes by systematic gene overexpression.

Q8NDF8	PAPD5_HUMAN	PAP-associated domain-containing protein 5	18172165	Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'.

P46736	BRCC3_HUMAN	Lys-63-specific deubiquitinase BRCC36	19261748	MERIT40 facilitates BRCA1 localization and DNA damage repair.

Q96502	COL2_ARATH	Zinc finger protein CONSTANS-LIKE 2	11359606	Analysis of the function of two circadian-regulated CONSTANS-LIKE genes.

Q9HCY8	S10AE_HUMAN	Protein S100-A14	11944983	Molecular cloning and characterization of the human S100A14 gene encoding a novel member of the S100 family.

Q9ULK4	MED23_HUMAN	Mediator of RNA polymerase II transcription subunit 23	9989412	The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1.

Q92633	LPAR1_HUMAN	Lysophosphatidic acid receptor 1	9070858	Molecular cloning of the human Edg2 protein and its identification as a functional cellular receptor for lysophosphatidic acid.

Q9W707	FXF1B_XENLA	Forkhead box protein F1-B	15656969	Of fox and frogs: fox (fork head/winged helix) transcription factors in Xenopus development.

P87315	HIR3_SCHPO	Histone transcription regulator 3 homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q02787	PURA_SCHPO	Adenylosuccinate synthetase	1448066	Purine biosynthetic genes are required for cadmium tolerance in Schizosaccharomyces pombe.

Q8N201	INT1_HUMAN	Integrator complex subunit 1	16239144	Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.

Q9UNE0	EDAR_HUMAN	Tumor necrosis factor receptor superfamily member EDAR	11035039	The ectodermal dysplasia receptor activates the nuclear factor- kappaB, JNK, and cell death pathways and binds to ectodysplasin A.

Q8BQU6	CXG2_MOUSE	Gap junction gamma-2 protein	11160382	Functional expression of the new gap junction gene connexin47 transcribed in mouse brain and spinal cord neurons.

P39687	AN32A_HUMAN	Acidic leucine-rich nuclear phosphoprotein 32 family member A	11729309	Delineation of mRNA export pathways by the use of cell-permeable peptides.

Q12406	ARP7_YEAST	Actin-related protein 7	12183366	Chromatin remodeling by RSC involves ATP-dependent DNA translocation.

Q9FGM1	PYL8_ARATH	Abscisic acid receptor PYL8	19407143	Regulators of PP2C phosphatase activity function as abscisic acid sensors.

Q6NUQ1	RINT1_HUMAN	RAD50-interacting protein 1	15029241	Implication of ZW10 in membrane trafficking between the endoplasmic reticulum and Golgi.

P14652	HXB2_HUMAN	Homeobox protein Hox-B2	7876223	Transcription factor GATA-1 regulates human HOXB2 gene expression in erythroid cells.

P83584	FER_SOLLS	Ferredoxin	12620316	Large differences in amino acid sequences among ferredoxins from several species of genus Solanum.

Q01684	SPR6_YEAST	Sporulation-specific protein	2253272	Functional analysis of the sporulation-specific SPR6 gene of Saccharomyces cerevisiae.

P10081	IF4A_YEAST	ATP-dependent RNA helicase eIF4A	1502180	ATP hydrolysis by initiation factor 4A is required for translation initiation in Saccharomyces cerevisiae.

Q6AYX5	ODFP2_RAT	Outer dense fiber protein 2	9698445	Developmental expression of the 84-kDa ODF sperm protein: localization to both the cortex and medulla of outer dense fibers and to the connecting piece.

Q9BZL6	KPCD2_HUMAN	Serine/threonine-protein kinase D2	11062248	Molecular cloning and characterization of the human protein kinase D2. A novel member of the protein kinase d family of serine threonine kinases.

O43013	YBOE_SCHPO	Uncharacterized protein C2G2.14	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q6NXK8	ACCN2_MOUSE	Amiloride-sensitive cation channel 2, neuronal	11988176	The acid-activated ion channel ASIC contributes to synaptic plasticity, learning, and memory.

Q96KJ9	COX42_HUMAN	Cytochrome c oxidase subunit 4 isoform 2, mitochondrial	11311561	Mammalian subunit IV isoforms of cytochrome c oxidase.

Q6R6I6	RXFP1_RAT	Relaxin receptor 1	15566402	Identification and characterization of the mouse and rat relaxin receptors as the novel orthologues of human leucine-rich repeat- containing G-protein-coupled receptor 7.

O14370	BCA1_SCHPO	Branched-chain-amino-acid aminotransferase, mitochondrial	9483807	Characterization of a branched-chain amino-acid aminotransferase from Schizosaccharomyces pombe.

Q10426	RIK1_SCHPO	Chromatin modification-related protein rik1	16127433	Ubiquitin ligase component Cul4 associates with Clr4 histone methyltransferase to assemble heterochromatin.

Q8WWI1	LMO7_HUMAN	LIM domain only protein 7	10531035	Identification of a family of human F-box proteins.

O70132	FEV_RAT	Protein FEV	9468386	Pet-1, a novel ETS domain factor that can activate neuronal nAchR gene transcription.

Q9VFP2	RDX_DROME	Protein roadkill	16740475	A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor.

Q8WTC1	RT15_DROME	28S ribosomal protein S15, mitochondrial	10225996	Cell-autonomous and non-autonomous growth-defective mutants of Drosophila melanogaster.

P35822	PTPRK_MOUSE	Receptor-type tyrosine-protein phosphatase kappa	8474452	Cloning and characterization of R-PTP-kappa, a new member of the receptor protein tyrosine phosphatase family with a proteolytically cleaved cellular adhesion molecule-like extracellular region.

O00219	HAS3_HUMAN	Hyaluronan synthase 3	9083017	Molecular cloning and characterization of a cDNA encoding the third putative mammalian hyaluronan synthase.

Q9P374	YLM7_SCHPO	Zinc finger protein C19B12.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q05809	YL218_YEAST	Coiled-coil-helix-coiled-coil-helix domain-containing protein YLR218C	14562095	Global analysis of protein localization in budding yeast.

Q9H015	S22A4_HUMAN	Solute carrier family 22 member 4	9426230	Cloning and characterization of a novel human pH-dependent organic cation transporter, OCTN1.

Q16619	CTF1_HUMAN	Cardiotrophin-1	8833032	Human cardiotrophin-1: protein and gene structure, biological and binding activities, and chromosomal localization.

P28572	SC6A9_RAT	Sodium- and chloride-dependent glycine transporter 1	1534013	Cloning and expression of a glycine transporter reveal colocalization with NMDA receptors.

Q9LTH9	ZIP2_ARATH	Zinc transporter 2	13129917	Expression profiles of Arabidopsis thaliana in mineral deficiencies reveal novel transporters involved in metal homeostasis.

Q05515	SVF1_YEAST	Survival factor 1	14562095	Global analysis of protein localization in budding yeast.

P21941	MATN1_HUMAN	Cartilage matrix protein	2246248	Structure and chromosomal location of the human gene encoding cartilage matrix protein.

O75791	GRAP2_HUMAN	GRB2-related adapter protein 2	9878555	Molecular cloning and expression of human grap-2, a novel leukocyte- specific SH2- and SH3-containing adaptor-like protein that binds to gab-1.

P38770	BRL1_YEAST	Nucleus export protein BRL1	15882446	Brl1p - a novel nuclear envelope protein required for nuclear transport.

Q8R2F2	DEGS2_MOUSE	Sphingolipid delta(4)-desaturase/C4-hydroxylase DES2	11937514	Identification and characterization of a sphingolipid delta 4- desaturase family.

P82538	PPL1_ARATH	PsbP-like protein 1, chloroplastic	11719511	Proteome map of the chloroplast lumen of Arabidopsis thaliana.

Q01590	SED5_YEAST	Integral membrane protein SED5	1400588	SED5 encodes a 39-kD integral membrane protein required for vesicular transport between the ER and the Golgi complex.

P24539	AT5F1_HUMAN	ATP synthase subunit b, mitochondrial	1831354	Molecular cloning of cDNA for the import precursor of human subunit B of H(+)-ATP synthase in mitochondria.

Q38845	2AAA_ARATH	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform	11449059	Genetic and chemical reductions in protein phosphatase activity alter auxin transport, gravity response, and lateral root growth.

Q96WW1	YNH8_SCHPO	Uncharacterized mannosyltransferase C32H8.08c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q4KMG0	CDON_HUMAN	Cell adhesion molecule-related/down-regulated by oncogenes	9214393	CDO: an oncogene-, serum-, and anchorage-regulated member of the Ig/fibronectin type III repeat family.

O76689	SNF6_CAEEL	Sodium-dependent acetylcholine transporter	15318222	SNF-6 is an acetylcholine transporter interacting with the dystrophin complex in Caenorhabditis elegans.

Q03206	RAC1_CAEEL	Ras-related protein ced-10	10707082	CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans.

Q2NKJ3	CTC1_HUMAN	CST complex subunit CTC1	19854130	RPA-like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathway.

P42765	THIM_HUMAN	3-ketoacyl-CoA thiolase, mitochondrial	8241273	Cloning and sequence analysis of a full length cDNA encoding human mitochondrial 3-oxoacyl-CoA thiolase.

O42173	PV1_XENLA	Homeobox protein pv.1	11944926	Antimorphic PV.1 causes secondary axis by inducing ectopic organizer.

P70169	DOC2B_MOUSE	Double C2-like domain-containing protein beta	20150444	Doc2b is a high-affinity Ca2+ sensor for spontaneous neurotransmitter release.

A0MES8	ABI4_ARATH	Ethylene-responsive transcription factor ABI4	10629000	Genetic analysis of salt-tolerant mutants in Arabidopsis thaliana.

Q00310	KRE2_CANAL	Glycolipid 2-alpha-mannosyltransferase	9636208	Molecular analysis of CaMnt1p, a mannosyl transferase important for adhesion and virulence of Candida albicans.

P07727	GLRA1_RAT	Glycine receptor subunit alpha-1	1703526	Alternative splicing generates two variants of the alpha 1 subunit of the inhibitory glycine receptor.

Q9FYE1	MCA9_ARATH	Metacaspase-9	17110382	Metacaspase activity of Arabidopsis thaliana is regulated by S- nitrosylation of a critical cysteine residue.

O94324	PPK31_SCHPO	Serine/threonine-protein kinase ppk31	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P24228	DACB_ECOLI	D-alanyl-D-alanine carboxypeptidase dacB	2046551	Penicillin-binding protein 4 of Escherichia coli: molecular cloning of the dacB gene, controlled overexpression, and alterations in murein composition.

Q99KQ4	NAMPT_MOUSE	Nicotinamide phosphoribosyltransferase	15381699	The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells.

Q24255	BARH1_DROME	Homeobox protein B-H1	1350558	Subtype determination of Drosophila embryonic external sensory organs by redundant homeo box genes BarH1 and BarH2.

P17952	MURC_ECOLI	UDP-N-acetylmuramate--L-alanine ligase	7601127	Over-production, purification and properties of the uridine- diphosphate-N-acetylmuramate:L-alanine ligase from Escherichia coli.

Q99728	BARD1_HUMAN	BRCA1-associated RING domain protein 1	10477523	Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50.

Q61584	FXR1_MOUSE	Fragile X mental retardation syndrome-related protein 1	15128702	Fxr1 knockout mice show a striated muscle phenotype: implications for Fxr1p function in vivo.

O94506	RSM1_SCHPO	mRNA export factor rsm1	15357289	Schizosaccharomyces pombe rsm1 genetically interacts with spmex67, which is involved in mRNA export.

O95248	MTMR5_HUMAN	Myotubularin-related protein 5	9736772	Characterization of the myotubularin dual specificity phosphatase gene family from yeast to human.

Q9WU74	LSR_RAT	Lipolysis-stimulated lipoprotein receptor	10224102	Molecular cloning of a lipolysis-stimulated remnant receptor expressed in the liver.

P56589	PEX3_HUMAN	Peroxisomal biogenesis factor 3	9657383	Cloning and characterization of the gene encoding the human peroxisomal assembly protein Pex3p.

P36871	PGM1_HUMAN	Phosphoglucomutase-1	7902568	The classical human phosphoglucomutase (PGM1) isozyme polymorphism is generated by intragenic recombination.

O43812	DUX1_HUMAN	Double homeobox protein 1	9736770	Characterization of a double homeodomain protein (DUX1) encoded by a cDNA homologous to 3.3-kb dispersed repeated elements.

Q9JHW5	VAMP7_RAT	Vesicle-associated membrane protein 7	16495485	Vesicle-associated membrane protein 7 is expressed in intestinal ER.

P27197	AURB_CHLAA	Auracyanin-B	1313011	Isolation, characterization, and amino acid sequences of auracyanins, blue copper proteins from the green photosynthetic bacterium Chloroflexus aurantiacus.

P25613	ADY2_YEAST	Accumulation of dyads protein 2	14968426	Ady2p is essential for the acetate permease activity in the yeast Saccharomyces cerevisiae.

Q9QXT8	CSEN_MOUSE	Calsenilin	14534243	Altered Abeta formation and long-term potentiation in a calsenilin knock-out.

P51811	XK_HUMAN	Membrane transport protein XK	7737196	Purification and partial characterization of the erythrocyte Kx protein deficient in McLeod patients.

Q04359	SPO20_YEAST	Sporulation-specific protein 20	10924463	Identification of domains required for developmentally regulated SNARE function in Saccharomyces cerevisiae.

Q3E785	SDHF1_YEAST	Succinate dehydrogenase assembly factor 1 homolog, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

P58181	O10A3_HUMAN	Olfactory receptor 10A3	1370859	Expression of members of the putative olfactory receptor gene family in mammalian germ cells.

Q9JLN5	ERMAP_MOUSE	Erythroid membrane-associated protein	10721728	Ermap, a gene coding for a novel erythroid specific adhesion/receptor membrane protein.

Q9LK35	THE1_ARATH	Receptor-like protein kinase THESEUS 1	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P28222	5HT1B_HUMAN	5-hydroxytryptamine receptor 1B	1559993	Molecular cloning of a human serotonin receptor (S12) with a pharmacological profile resembling that of the 5-HT1D subtype.

P40061	TSC11_YEAST	Target of rapamycin complex 2 subunit TSC11	12631735	Tor kinases are in distinct membrane-associated protein complexes in Saccharomyces cerevisiae.

P33310	MDL1_YEAST	ATP-dependent permease MDL1, mitochondrial	11251115	Role of the ABC transporter Mdl1 in peptide export from mitochondria.

Q9ZPQ3	GEK1_ARATH	D-aminoacyl-tRNA deacylase	17251192	GEK1, a gene product of Arabidopsis thaliana involved in ethanol tolerance, is a D-aminoacyl-tRNA deacylase.

Q9ULL8	SHRM4_HUMAN	Protein Shroom4	16684770	Differential actin-dependent localization modulates the evolutionarily conserved activity of Shroom family proteins.

Q13492	PICAL_HUMAN	Phosphatidylinositol-binding clathrin assembly protein	8643484	The t(10;11)(p13;q14) in the U937 cell line results in the fusion of the AF10 gene and CALM, encoding a new member of the AP-3 clathrin assembly protein family.

Q92457	AGAL2_TRIRE	Alpha-galactosidase 2	8797842	Three alpha-galactosidase genes of Trichoderma reesei cloned by expression in yeast.

P83434	NLTP1_PHAAU	Non-specific lipid-transfer protein 1	15350690	A non-specific lipid transfer protein with antifungal and antibacterial activities from the mung bean.

Q99728	BARD1_HUMAN	BRCA1-associated RING domain protein 1	8944023	Identification of a RING protein that can interact in vivo with the BRCA1 gene product.

P32434	PGTB1_SCHPO	Geranylgeranyl transferase type-1 subunit beta	8262067	The Schizosaccharomyces pombe cwg2+ gene codes for the beta subunit of a geranylgeranyltransferase type I required for beta-glucan synthesis.

Q8TB61	S35B2_HUMAN	Adenosine 3'-phospho 5'-phosphosulfate transporter 1	12716889	Molecular cloning and identification of 3'-phosphoadenosine 5'- phosphosulfate transporter.

Q7Z7A4	PXK_HUMAN	PX domain-containing protein kinase-like protein	16142408	Expression pattern and subcellular localization of five splice isoforms of human PXK.

P79005	TAZ1_SCHPO	Telomere length regulator taz1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O94716	FTA4_SCHPO	Kinetochore protein fta4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q53FV1	ORML2_HUMAN	ORM1-like protein 2	12093374	ORMDL proteins are a conserved new family of endoplasmic reticulum membrane proteins.

P17649	GATA_YEAST	4-aminobutyrate aminotransferase	3888627	Mutations affecting the enzymes involved in the utilization of 4- aminobutyric acid as nitrogen source by the yeast Saccharomyces cerevisiae.

P41930	SSU1_YEAST	Sulfite efflux pump SSU1	9294463	SSU1 encodes a plasma membrane protein with a central role in a network of proteins conferring sulfite tolerance in Saccharomyces cerevisiae.

P46677	TAF1_YEAST	Transcription initiation factor TFIID subunit 1	8980232	The TAF(II)250 subunit of TFIID has histone acetyltransferase activity.

Q04632	COG8_YEAST	Conserved oligomeric Golgi complex subunit 8	11703943	The Sec34/35 Golgi transport complex is related to the exocyst, defining a family of complexes involved in multiple steps of membrane traffic.

P97546	NPTN_RAT	Neuroplastin	10759566	The synaptic glycoprotein neuroplastin is involved in long-term potentiation at hippocampal CA1 synapses.

P31551	CAID_ECOLI	Carnitinyl-CoA dehydratase	7815937	Molecular characterization of the cai operon necessary for carnitine metabolism in Escherichia coli.

Q09722	EIF3M_SCHPO	Eukaryotic translation initiation factor 3 subunit M	15904532	PCI proteins eIF3e and eIF3m define distinct translation initiation factor 3 complexes.

O14936	CSKP_HUMAN	Peripheral plasma membrane protein CASK	18423203	CASK functions as a Mg2+-independent neurexin kinase.

Q7D6W6	PISA_MYCTU	CDP-diacylglycerol--inositol 3-phosphatidyltransferase	10889206	Phosphatidylinositol is an essential phospholipid of mycobacteria.

P81916	OR33C_DROME	Odorant receptor 33c	10089887	A spatial map of olfactory receptor expression in the Drosophila antenna.

Q12125	GET4_YEAST	Golgi to ER traffic protein 4	20106980	Crystal structure of Get4-Get5 complex and its interactions with Sgt2, Get3, and Ydj1.

Q05209	PTN12_HUMAN	Tyrosine-protein phosphatase non-receptor type 12	1472029	Cloning and characterization of a human cDNA encoding a novel putative cytoplasmic protein-tyrosine-phosphatase.

Q8H166	ALEU_ARATH	Thiol protease aleurain	8518555	Developmental and age-related processes that influence the longevity and senescence of photosynthetic tissues in Arabidopsis.

P11972	SST2_YEAST	Protein SST2	2830483	Pheromonal regulation and sequence of the Saccharomyces cerevisiae SST2 gene: a model for desensitization to pheromone.

Q27371	TNNT_CAEEL	Troponin T	8601585	Developmental genetic analysis of troponin T mutations in striated and nonstriated muscle cells of Caenorhabditis elegans.

Q80Z39	G109A_RAT	G-protein coupled receptor 109A	19141678	Niacin stimulates adiponectin secretion through the GPR109A receptor.

Q08230	SDHF2_YEAST	Succinate dehydrogenase assembly factor 2, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

P20794	MAK_HUMAN	Serine/threonine-protein kinase MAK	2183027	A novel mammalian protein kinase gene (mak) is highly expressed in testicular germ cells at and after meiosis.

Q80X90	FLNB_MOUSE	Filamin-B	12393796	Filamin A and filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact.

Q54PC2	GSH1_DICDI	Glutamate--cysteine ligase	15993406	Glutathione is required for growth and prespore cell differentiation in Dictyostelium.

P24870	CG23_YEAST	G2/mitotic-specific cyclin-3	1387566	Characterization of four B-type cyclin genes of the budding yeast Saccharomyces cerevisiae.

Q9SCT4	IMK2_ARATH	Probably inactive leucine-rich repeat receptor-like protein kinase IMK2	17644812	A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome.

P38211	GPI18_YEAST	GPI mannosyltransferase 2	15623507	PIG-V involved in transferring the second mannose in glycosylphosphatidylinositol.

P46985	MNN11_YEAST	Probable alpha-1,6-mannosyltransferase MNN11	10037752	The Saccharomyces cerevisiae protein Mnn10p/Bed1p is a subunit of a Golgi mannosyltransferase complex.

Q12464	RUVB2_YEAST	RuvB-like protein 2	11604509	A well-connected and conserved nucleoplasmic helicase is required for production of box C/D and H/ACA snoRNAs and localization of snoRNP proteins.

Q9GZQ4	NMUR2_HUMAN	Neuromedin-U receptor 2	10894543	Identification of receptors for neuromedin U and its role in feeding.

Q24048	ATPB2_DROME	Sodium/potassium-transporting ATPase subunit beta-2	9648860	Functional analysis and tissue-specific expression of Drosophila Na+,K+-ATPase subunits.

P52888	THOP1_HUMAN	Thimet oligopeptidase	7639763	Cloning and functional expression of a metalloendopeptidase from human brain with the ability to cleave a beta-APP substrate peptide.

Q1MTP1	YGIB_SCHPO	UPF0666 protein C2A9.11c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Y0H4	SUDX_DROME	E3 ubiquitin-protein ligase Su(dx)	10353900	The Drosophila melanogaster Suppressor of deltex gene, a regulator of the Notch receptor signaling pathway, is an E3 class ubiquitin ligase.

P40205	NCYM_HUMAN	N-cym protein	1419902	Isolation and characterization of complementary DNA for N-cym, a gene encoded by the DNA strand opposite to N-myc.

Q00916	RU17_YEAST	U1 small nuclear ribonucleoprotein 70 kDa homolog	11425851	New roles for the Snp1 and Exo84 proteins in yeast pre-mRNA splicing.

P32447	ASF1_YEAST	Histone chaperone ASF1	11731480	The silencing complex SAS-I links histone acetylation to the assembly of repressed chromatin by CAF-I and Asf1 in Saccharomyces cerevisiae.

Q61818	RAI1_MOUSE	Retinoic acid-induced protein 1	15746153	Inactivation of Rai1 in mice recapitulates phenotypes observed in chromosome engineered mouse models for Smith-Magenis syndrome.

Q80YV2	NIPA_MOUSE	Nuclear-interacting partner of ALK	12748172	Identification and characterization of a nuclear interacting partner of anaplastic lymphoma kinase (NIPA).

Q38954	PHT21_ARATH	Inorganic phosphate transporter 2-1, chloroplastic	12172020	A chloroplast phosphate transporter, PHT2;1, influences allocation of phosphate within the plant and phosphate-starvation responses.

P38880	MDM31_YEAST	Mitochondrial distribution and morphology protein 31	15631992	Mdm31 and Mdm32 are inner membrane proteins required for maintenance of mitochondrial shape and stability of mitochondrial DNA nucleoids in yeast.

P39990	SNU13_YEAST	13 kDa ribonucleoprotein-associated protein	10377396	Purification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins.

P40963	SAS2_YEAST	Histone acetyltransferase SAS2	11731480	The silencing complex SAS-I links histone acetylation to the assembly of repressed chromatin by CAF-I and Asf1 in Saccharomyces cerevisiae.

P35180	TOM20_YEAST	Mitochondrial import receptor subunit TOM20	8132642	Deletion of the receptor MOM19 strongly impairs import of cleavable preproteins into Saccharomyces cerevisiae mitochondria.

Q9NII1	ADAR_DROME	Double-stranded RNA-specific editase Adar	11254668	Mutation in pre-mRNA adenosine deaminase markedly attenuates neuronal tolerance to O(2) deprivation in Drosophila melanogaster.

P05362	ICAM1_HUMAN	Intercellular adhesion molecule 1	2538243	The major human rhinovirus receptor is ICAM-1.

P41440	S19A1_HUMAN	Folate transporter 1	7826387	Molecular cloning of the human placental folate transporter.

Q9H173	SIL1_HUMAN	Nucleotide exchange factor SIL1	11101517	LHS1 and SIL1 provide a lumenal function that is essential for protein translocation into the endoplasmic reticulum.

O74803	RHP23_SCHPO	UV excision repair protein rhp23	11788722	Involvement of rhp23, a Schizosaccharomyces pombe homolog of the human HHR23A and Saccharomyces cerevisiae RAD23 nucleotide excision repair genes, in cell cycle control and protein ubiquitination.

P61586	RHOA_HUMAN	Transforming protein RhoA	11927263	MgF(3)(-) as a transition state analog of phosphoryl transfer.

Q15545	TAF7_HUMAN	Transcription initiation factor TFIID subunit 7	7824954	Cloning of an intrinsic human TFIID subunit that interacts with multiple transcriptional activators.

Q9VKM1	PIWI_DROME	Protein piwi	10631171	piwi encodes a nucleoplasmic factor whose activity modulates the number and division rate of germline stem cells.

O24409	IAA19_ARATH	Auxin-responsive protein IAA19	12036262	Genetics of Aux/IAA and ARF action in plant growth and development.

P96796	HDRE_METBF	CoB--CoM heterodisulfide reductase subunit E	9063468	Heterodisulfide reductase from methanol-grown cells of Methanosarcina barkeri is not a flavoenzyme.

O48671	RER1B_ARATH	Protein RER1B	10737146	The Arabidopsis thaliana RER1 gene family: its potential role in the endoplasmic reticulum localization of membrane proteins.

P14922	CYC8_YEAST	General transcriptional corepressor CYC8	14525981	Tup1-Ssn6 interacts with multiple class I histone deacetylases in vivo.

Q13315	ATM_HUMAN	Serine-protein kinase ATM	9733515	Activation of the ATM kinase by ionizing radiation and phosphorylation of p53.

Q92730	RND1_HUMAN	Rho-related GTP-binding protein Rho6	10664463	Interaction of the Grb7 adapter protein with Rnd1, a new member of the Rho family.

P11708	MDHC_PIG	Malate dehydrogenase, cytoplasmic	3312200	Cloning and sequence analysis of cDNAs encoding mammalian cytosolic malate dehydrogenase. Comparison of the amino acid sequences of mammalian and bacterial malate dehydrogenase.

P08521	AAP_YEAST	Arginine attenuator peptide	10608810	A highly conserved mechanism of regulated ribosome stalling mediated by fungal arginine attenuator peptides that appears independent of the charging status of arginyl-tRNAs.

Q15024	EXOS7_HUMAN	Exosome complex exonuclease RRP42	15231747	A protein interaction framework for human mRNA degradation.

P87061	TEA1_SCHPO	Tip elongation aberrant protein 1	15809031	Tea4p links microtubule plus ends with the formin for3p in the establishment of cell polarity.

P53011	SEH1_YEAST	Nucleoporin SEH1	11823431	Modular self-assembly of a Y-shaped multiprotein complex from seven nucleoporins.

O42868	SSU72_SCHPO	RNA polymerase II subunit A C-terminal domain phosphatase ssu72	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O74545	YCV6_SCHPO	Putative hydrolase C777.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

C0LU16	MED21_ARATH	Mediator of RNA polymerase II transcription subunit 21	19286969	HISTONE MONOUBIQUITINATION1 interacts with a subunit of the mediator complex and regulates defense against necrotrophic fungal pathogens in Arabidopsis.

P31512	FMO4_HUMAN	Dimethylaniline monooxygenase [N-oxide-forming] 4	1417778	Cloning, primary sequence and chromosomal localization of human FMO2, a new member of the flavin-containing mono-oxygenase family.

Q9XFS9	DXR_ARATH	1-deoxy-D-xylulose 5-phosphate reductoisomerase, chloroplastic	10428488	Cloning and heterologous expression of a cDNA encoding 1-deoxy-D- xylulose-5-phosphate reductoisomerase of Arabidopsis thaliana.

Q06263	VTA1_YEAST	Vacuolar protein sorting-associated protein VTA1	14701806	Characterization of Vta1p, a class E Vps protein in Saccharomyces cerevisiae.

Q9W596	FUTSC_DROME	Microtubule-associated protein futsch	10839356	Drosophila Futsch regulates synaptic microtubule organization and is necessary for synaptic growth.

Q9UKP6	UR2R_HUMAN	Urotensin-2 receptor	10499587	Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14.

Q14164	IKKE_HUMAN	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	10421793	IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IkappaB kinases.

P50091	PEX21_YEAST	Peroxisomal membrane protein PEX21	17451428	Peroxin Pex21p interacts with the C-terminal noncatalytic domain of yeast seryl-tRNA synthetase and forms a specific ternary complex with tRNA(Ser).

O43463	SUV91_HUMAN	Histone-lysine N-methyltransferase SUV39H1	18485871	Epigenetic control of rDNA loci in response to intracellular energy status.

P31353	PMM_CANAL	Phosphomannomutase	1473182	The Candida albicans PMM1 gene encoding phosphomannomutase complements a Saccharomyces cerevisiae sec 53-6 mutation.

O94547	SRK1_SCHPO	Serine/threonine-protein kinase srk1	12080074	The Srk1 protein kinase is a target for the Sty1 stress-activated MAPK in fission yeast.

Q08873	SCP1_YEAST	Transgelin	12857851	The Saccharomyces cerevisiae calponin/transgelin homolog Scp1 functions with fimbrin to regulate stability and organization of the actin cytoskeleton.

O74378	ODO1_SCHPO	2-oxoglutarate dehydrogenase, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NP08	HMX1_HUMAN	Homeobox protein HMX1	10206974	Transcriptional antagonism between Hmx1 and Nkx2.5 for a shared DNA- binding site.

Q9U357	PEN2_CAEEL	Gamma-secretase subunit pen-2	12110170	aph-1 and pen-2 are required for Notch pathway signaling, gamma- secretase cleavage of betaAPP, and presenilin protein accumulation.

Q63100	DC1I1_RAT	Cytoplasmic dynein 1 intermediate chain 1	1387402	Homology of the 74-kD cytoplasmic dynein subunit with a flagellar dynein polypeptide suggests an intracellular targeting function.

Q9UUH6	YKI6_SCHPO	Uncharacterized nucleolar protein C630.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P34227	PRX1_YEAST	Mitochondrial peroxiredoxin PRX1	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

O94607	STR2_SCHPO	Siderophore iron transporter 2	12888492	Fep1 represses expression of the fission yeast Schizosaccharomyces pombe siderophore-iron transport system.

Q9UMS0	NFU1_HUMAN	NFU1 iron-sulfur cluster scaffold homolog, mitochondrial	12886008	Subcellular compartmentalization of human Nfu, an iron-sulfur cluster scaffold protein, and its ability to assemble a [4Fe-4S] cluster.

P40999	PMT1M_SCHPO	DNA methyltransferase homolog pmt1	8636983	Activation of a yeast pseudo DNA methyltransferase by deletion of a single amino acid.

P20062	TCO2_HUMAN	Transcobalamin-2	1708393	The cDNA sequence and the deduced amino acid sequence of human transcobalamin II show homology with rat intrinsic factor and human transcobalamin I.

P35195	ECM15_YEAST	UPF0045 protein ECM15	14562095	Global analysis of protein localization in budding yeast.

P52955	LBX1_MOUSE	Transcription factor LBX1	12062039	The homeodomain factor lbx1 distinguishes two major programs of neuronal differentiation in the dorsal spinal cord.

Q8C8N3	VWC2_MOUSE	Brorin	17400546	Brorin, a novel secreted bone morphogenetic protein antagonist, promotes neurogenesis in mouse neural precursor cells.

P62736	ACTA_HUMAN	Actin, aortic smooth muscle	16548883	Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection.

O14284	OXR1_SCHPO	Oxidation resistance protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

B6JUP5	VASA2_DROME	Sister chromatid cohesion vasa, isoform solo	20142422	SOLO: a meiotic protein required for centromere cohesion, coorientation, and SMC1 localization in Drosophila melanogaster.

Q04659	CSM3_YEAST	Chromosome segregation in meiosis protein 3	11470404	A screen for genes required for meiosis and spore formation based on whole-genome expression.

Q38879	TRXH2_ARATH	Thioredoxin H2	20133584	A membrane-associated thioredoxin required for plant growth moves from cell to cell, suggestive of a role in intercellular communication.

Q9JHF9	LY96_MOUSE	Lymphocyte antigen 96	17803912	Crystal structure of the TLR4-MD-2 complex with bound endotoxin antagonist Eritoran.

P27487	DPP4_HUMAN	Dipeptidyl peptidase 4	8101391	Direct association of adenosine deaminase with a T cell activation antigen, CD26.

Q9Z0F3	B2L10_MOUSE	Bcl-2-like protein 10	9829980	Diva, a Bcl-2 homologue that binds directly to Apaf-1 and induces BH3-independent cell death.

P47002	SSY5_YEAST	SPS-sensor serine protease component SSY5	16778074	Regulation of transcription factor latency by receptor-activated proteolysis.

P53600	COPZ_YEAST	Coatomer subunit zeta	8617224	Delta- and zeta-COP, two coatomer subunits homologous to clathrin- associated proteins, are involved in ER retrieval.

P36877	2ABB_RAT	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform	8389301	Expression of PP2A B regulatory subunit beta isotype in rat testis.

Q9C8K2	AB12G_ARATH	ABC transporter G family member 12	11336252	Cuticular waxes on eceriferum mutants of Arabidopsis thaliana.

Q9NVC6	MED17_HUMAN	Mediator of RNA polymerase II transcription subunit 17	10235266	Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex.

P41878	RPN11_SCHPO	26S proteasome regulatory subunit rpn11	9727008	The pad1+ gene encodes a subunit of the 26 S proteasome in fission yeast.

Q23255	MRE11_CAEEL	Double-strand break repair protein mre-11	11238374	C. elegans mre-11 is required for meiotic recombination and DNA repair but is dispensable for the meiotic G(2) DNA damage checkpoint.

O43462	MBTP2_HUMAN	Membrane-bound transcription factor site-2 protease	9659902	Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPs.

Q13522	PPR1A_HUMAN	Protein phosphatase 1 regulatory subunit 1A	8611507	Multiple structural elements define the specificity of recombinant human inhibitor-1 as a protein phosphatase-1 inhibitor.

Q9Z0E8	S22A5_MOUSE	Solute carrier family 22 member 5	15523054	PDZK1 directly regulates the function of organic cation/carnitine transporter OCTN2.

Q00IB6	CPL4_ARATH	RNA polymerase II C-terminal domain phosphatase-like 4	16905668	Arabidopsis carboxyl-terminal domain phosphatase-like isoforms share common catalytic and interaction domains but have distinct in planta functions.

Q99961	SH3G1_HUMAN	Endophilin-A2	9169142	A novel SH3-containing human gene family preferentially expressed in the central nervous system.

Q0JKD0	GLT1_ORYSJ	Glutamate synthase 1 [NADH]	9952435	Quantitative intercellular localization of NADH-dependent glutamate synthase protein in different types of root cells in rice plants.

P16622	HEMH_YEAST	Ferrochelatase, mitochondrial	2185242	The ferrochelatase from Saccharomyces cerevisiae. Sequence, disruption, and expression of its structural gene HEM15.

P21900	PURA_DICDI	Adenylosuccinate synthetase	1989999	Purification and cDNA-derived sequence of adenylosuccinate synthetase from Dictyostelium discoideum.

Q06630	MHR1_YEAST	Mitochondrial homologous recombination protein 1	9736700	A novel yeast protein influencing the response of RNA polymerase II to transcriptional activators.

Q9VG55	HUGIN_DROME	Protein hugin	12204246	The Drosophila hugin gene codes for myostimulatory and ecdysis- modifying neuropeptides.

P31751	AKT2_HUMAN	RAC-beta serine/threonine-protein kinase	20059950	The E3 ligase TTC3 facilitates ubiquitination and degradation of phosphorylated Akt.

P32468	CDC12_YEAST	Cell division control protein 12	9813094	Polymerization of purified yeast septins: evidence that organized filament arrays may not be required for septin function.

Q9XJ35	CLPR1_ARATH	ATP-dependent Clp protease proteolytic subunit-related protein 1, chloroplastic	14593120	Clp protease complexes from photosynthetic and non-photosynthetic plastids and mitochondria of plants, their predicted three-dimensional structures, and functional implications.

O65420	VAL3_ARATH	B3 domain-containing transcription factor VAL3	17158584	Repression of the LEAFY COTYLEDON 1/B3 regulatory network in plant embryo development by VP1/ABSCISIC ACID INSENSITIVE 3-LIKE B3 genes.

Q9UN74	PCDA4_HUMAN	Protocadherin alpha-4	10380929	A striking organization of a large family of human neural cadherin- like cell adhesion genes.

Q8LAD7	IDA_ARATH	Protein IDA	18660431	The EPIP peptide of INFLORESCENCE DEFICIENT IN ABSCISSION is sufficient to induce abscission in arabidopsis through the receptor- like kinases HAESA and HAESA-LIKE2.

P0C0V8	RS21A_YEAST	40S ribosomal protein S21-A	14627813	Ribosomal proteins Rps0 and Rps21 of Saccharomyces cerevisiae have overlapping functions in the maturation of the 3' end of 18S rRNA.

O96433	CCNT_DROME	Cyclin-T	9593731	Identification of a cyclin subunit required for the function of Drosophila P-TEFb.

P07864	LDHC_HUMAN	L-lactate dehydrogenase C chain	2440048	Epitopes of human testis-specific lactate dehydrogenase deduced from a cDNA sequence.

Q6IFV3	K1C15_RAT	Keratin, type I cytoskeletal 15	15085952	Comprehensive analysis of keratin gene clusters in humans and rodents.

Q9JI33	NET4_MOUSE	Netrin-4	11038171	A novel member of the netrin family, beta-netrin, shares homology with the beta chain of laminin. Identification, expression, and functional characterization.

P21817	RYR1_HUMAN	Ryanodine receptor 1	2298749	Molecular cloning of cDNA encoding human and rabbit forms of the Ca2+ release channel (ryanodine receptor) of skeletal muscle sarcoplasmic reticulum.

Q8NG41	NPB_HUMAN	Neuropeptide B	12118011	Identification of a neuropeptide modified with bromine as an endogenous ligand for GPR7.

P86052	CYC4_THIRO	Cytochrome c4	17931594	Oxygen and temperature-dependent structural and redox changes in a novel cytochrome c(4) from the purple sulfur photosynthetic bacterium Thiocapsa roseopersicina.

O43395	PRPF3_HUMAN	U4/U6 small nuclear ribonucleoprotein Prp3	9328476	Identification and characterization of human genes encoding Hprp3p and Hprp4p, interacting components of the spliceosome.

P32500	NDC1_YEAST	Nucleoporin NDC1	11283351	A comprehensive two-hybrid analysis to explore the yeast protein interactome.

Q8BYR2	LATS1_MOUSE	Serine/threonine-protein kinase LATS1	9988269	Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction.

Q8BGC9	CREG2_MOUSE	Protein CREG2	12408961	Identification and characterization of novel members of the CREG family, putative secreted glycoproteins expressed specifically in brain.

Q23022	ACH5_CAEEL	Acetylcholine receptor subunit alpha-type unc-38	9221782	Caenorhabditis elegans levamisole resistance genes lev-1, unc-29, and unc-38 encode functional nicotinic acetylcholine receptor subunits.

P51142	DVL2_XENLA	Segment polarity protein dishevelled homolog DVL-2	9076682	Graded amounts of Xenopus dishevelled specify discrete anteroposterior cell fates in prospective ectoderm.

O88575	S620B_MOUSE	Sodium- and chloride-dependent transporter XTRP3B	16174864	Luminal kidney and intestine SLC6 amino acid transporters of B0AT- cluster and their tissue distribution in Mus musculus.

Q9QXZ9	OPN4_MOUSE	Melanopsin	10632589	A novel human opsin in the inner retina.

P50549	ETV1_HUMAN	ETS translocation variant 1	7700648	A variant Ewing's sarcoma translocation (7;22) fuses the EWS gene to the ETS gene ETV1.

Q1JQ73	ELV1A_XENLA	ELAV-like protein 1-A	11780632	A 250-nucleotide UA-rich element in the 3' untranslated region of Xenopus laevis Vg1 mRNA represses translation both in vivo and in vitro.

Q9ESC8	AFF4_MOUSE	AF4/FMR2 family member 4	16024815	Infertility with defective spermiogenesis in mice lacking AF5q31, the target of chromosomal translocation in human infant leukemia.

O94532	FOR3_SCHPO	Formin-3	15809031	Tea4p links microtubule plus ends with the formin for3p in the establishment of cell polarity.

O14744	ANM5_HUMAN	Protein arginine N-methyltransferase 5	17709427	Two distinct arginine methyltransferases are required for biogenesis of Sm-class ribonucleoproteins.

P12236	ADT3_HUMAN	ADP/ATP translocase 3	2541251	DNA sequences of two expressed nuclear genes for human mitochondrial ADP/ATP translocase.

O00167	EYA2_HUMAN	Eyes absent homolog 2	19351884	Dephosphorylation of the C-terminal tyrosyl residue of the DNA damage-related histone H2A.X is mediated by the protein phosphatase eyes absent.

P46150	MOEH_DROME	Moesin/ezrin/radixin homolog 1	8666669	Distinct cellular and subcellular patterns of expression imply distinct functions for the Drosophila homologues of moesin and the neurofibromatosis 2 tumor suppressor, merlin.

O35412	SI1L1_RAT	Signal-induced proliferation-associated 1-like protein 1	11502259	Regulation of dendritic spine morphology by SPAR, a PSD-95-associated RapGAP.

Q8IZD2	MLL5_HUMAN	Histone-lysine N-methyltransferase MLL5	19377461	GlcNAcylation of a histone methyltransferase in retinoic-acid-induced granulopoiesis.

P32239	GASR_HUMAN	Gastrin/cholecystokinin type B receptor	10913157	Human colorectal cancers express a constitutively active cholecystokinin-B/gastrin receptor that stimulates cell growth.

Q9LIC6	PR1F3_ARATH	PRA1 family protein F3	18583532	The PRA1 gene family in Arabidopsis.

O15117	FYB_HUMAN	FYN-binding protein	9207119	Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain- containing leukocyte protein 76 and modulates interleukin 2 production.

O82768	HIS2_ARATH	Histidine biosynthesis bifunctional protein hisIE, chloroplastic	9733547	Isolation and characterization of a histidine biosynthetic gene in Arabidopsis encoding a polypeptide with two separate domains for phosphoribosyl-ATP pyrophosphohydrolase and phosphoribosyl-AMP cyclohydrolase.

P62072	TIM10_HUMAN	Mitochondrial import inner membrane translocase subunit Tim10	10552927	The human family of deafness/dystonia peptide (DDP) related mitochondrial import proteins.

Q1W694	B1Q_LOXIN	Sphingomyelin phosphodiesterase D LiSicTox-betaID1	17296256	Two novel dermonecrotic toxins LiRecDT4 and LiRecDT5 from Brown spider (Loxosceles intermedia) venom: from cloning to functional characterization.

Q60992	VAV2_MOUSE	Guanine nucleotide exchange factor VAV2	16782872	Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis.

O94759	TRPM2_HUMAN	Transient receptor potential cation channel subfamily M member 2	9806837	Molecular cloning of a novel putative Ca2+ channel protein (TRPC7) highly expressed in brain.

P55228	GLGS_ARATH	Glucose-1-phosphate adenylyltransferase small subunit, chloroplastic	9680965	Characterization of ADG1, an Arabidopsis locus encoding for ADPG pyrophosphorylase small subunit, demonstrates that the presence of the small subunit is required for large subunit stability.

Q54RV9	SGPL_DICDI	Sphingosine-1-phosphate lyase	11566853	Sphingosine-1-phosphate lyase has a central role in the development of Dictyostelium discoideum.

O00237	RN103_HUMAN	E3 ubiquitin-protein ligase RNF103	18675248	Ubiquitin ligase Kf-1 is involved in the endoplasmic reticulum- associated degradation pathway.

Q00975	CAC1B_HUMAN	Voltage-dependent N-type calcium channel subunit alpha-1B	1321501	Structure and functional expression of an omega-conotoxin-sensitive human N-type calcium channel.

O75908	SOAT2_HUMAN	Sterol O-acyltransferase 2	9756920	Characterization of two human genes encoding acyl coenzyme A:cholesterol acyltransferase-related enzymes.

O15078	CE290_HUMAN	Centrosomal protein of 290 kDa	16682973	The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4.

Q96A11	G3ST3_HUMAN	Galactose-3-O-sulfotransferase 3	11356829	A novel human Gal-3-O-sulfotransferase: molecular cloning, characterization, and its implications in biosynthesis of (SO4- 3)Galbeta 1-4(Fucalpha 1-3)GlcNAc.

A3KFF6	WBP2L_BOVIN	Postacrosomal sheath WW domain-binding protein	17289678	PAWP, a sperm-specific WW domain-binding protein, promotes meiotic resumption and pronuclear development during fertilization.

P36222	CH3L1_HUMAN	Chitinase-3-like protein 1	8245017	Human cartilage gp-39, a major secretory product of articular chondrocytes and synovial cells, is a mammalian member of a chitinase protein family.

Q04656	ATP7A_HUMAN	Copper-transporting ATPase 1	9467005	Constitutive skipping of alternatively spliced exon 10 in the ATP7A gene abolishes Golgi localization of the menkes protein and produces the occipital horn syndrome.

Q92674	CENPI_HUMAN	Centromere protein I	8921378	Sequence and chromosomal location of a human homologue of LRPR1, an FSH primary response gene.

P04803	SYWM_YEAST	Tryptophanyl-tRNA synthetase, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P27398	CAND_DROME	Calpain-D	1714593	Molecular cloning and analysis of small optic lobes, a structural brain gene of Drosophila melanogaster.

P35408	PE2R4_HUMAN	Prostaglandin E2 receptor EP4 subtype	8862514	Gene expression of the human prostaglandin E receptor EP4 subtype: differential regulation in monocytoid and lymphoid lineage cells by phorbol ester.

Q27J49	BNP_LACMU	Bradykinin-potentiating and C-type natriuretic peptides	16277978	Identification and functional analysis of a novel bradykinin inhibitory peptide in the venoms of new world crotalinae pit vipers.

P70056	FOXH1_XENLA	Forkhead box protein H1	12374795	Stoichiometry of active smad-transcription factor complexes on DNA.

O74999	RAD7_SCHPO	DNA repair protein rhp7	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P06100	NOT2_YEAST	General negative regulator of transcription subunit 2	11889048	Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae.

Q9Y7Z4	COG3_SCHPO	Conserved oligomeric Golgi complex subunit 3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P77211	CUSC_ECOLI	Cation efflux system protein cusC	11004187	Identification of a copper-responsive two-component system on the chromosome of Escherichia coli K-12.

Q9LDX1	SGS3_ARATH	Protein SUPPRESSOR OF GENE SILENCING 3	10850495	Arabidopsis SGS2 and SGS3 genes are required for posttranscriptional gene silencing and natural virus resistance.

P46673	NUP85_YEAST	Nucleoporin NUP85	11823431	Modular self-assembly of a Y-shaped multiprotein complex from seven nucleoporins.

P29590	PML_HUMAN	Probable transcription factor PML	18298799	Modulation of M2-type pyruvate kinase activity by the cytoplasmic PML tumor suppressor protein.

Q37145	ACA1_ARATH	Calcium-transporting ATPase 1, chloroplastic	8234257	Characterization of a gene encoding a Ca(2+)-ATPase-like protein in the plastid envelope.

P43321	SMD3_YEAST	Small nuclear ribonucleoprotein Sm D3	9012791	Identification of the proteins of the yeast U1 small nuclear ribonucleoprotein complex by mass spectrometry.

O60391	NMD3B_HUMAN	Glutamate [NMDA] receptor subunit 3B	11735224	Nucleotide sequence, genomic organization, and chromosomal localization of genes encoding the human NMDA receptor subunits NR3A and NR3B.

P26684	EDNRA_RAT	Endothelin-1 receptor	1849646	Cloning and functional expression of a vascular smooth muscle endothelin 1 receptor.

Q9Z0Y1	DCTN3_MOUSE	Dynactin subunit 3	9786090	Identification and molecular characterization of the p24 dynactin light chain.

Q92974	ARHG2_HUMAN	Rho guanine nucleotide exchange factor 2	9857026	Cloning and characterization of GEF-H1, a microtubule-associated guanine nucleotide exchange factor for Rac and Rho GTPases.

P0AER0	GLPF_ECOLI	Glycerol uptake facilitator protein	6998951	Substrate specificity and transport properties of the glycerol facilitator of Escherichia coli.

P0A7C2	LEXA_ECOLI	LexA repressor	7027256	Mechanism of action of the lexA gene product.

Q59HJ6	LONM_BOVIN	Lon protease homolog, mitochondrial	12198491	Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism.

O42978	LSM5_SCHPO	U6 snRNA-associated Sm-like protein LSm5	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P31750	AKT1_MOUSE	RAC-alpha serine/threonine-protein kinase	19778506	DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212.

P63280	UBC9_MOUSE	SUMO-conjugating enzyme UBC9	9409784	The mUBC9 murine ubiquitin conjugating enzyme interacts with the E2A transcription factors.

Q15691	MARE1_HUMAN	Microtubule-associated protein RP/EB family member 1	19543227	TIP150 interacts with and targets MCAK at the microtubule plus ends.

P51948	MAT1_HUMAN	CDK-activating kinase assembly factor MAT1	8521818	In vitro assembly of a functional human CDK7-cyclin H complex requires MAT1, a novel 36 kDa RING finger protein.

Q05469	LIPS_HUMAN	Hormone-sensitive lipase	17026959	Association and insulin regulated translocation of hormone-sensitive lipase with PTRF.

P53090	ARO8_YEAST	Aromatic amino acid aminotransferase 1	14562095	Global analysis of protein localization in budding yeast.

P20336	RAB3A_HUMAN	Ras-related protein Rab-3A	2501306	The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion.

O13023	HHEX_XENLA	Hematopoietically-expressed homeobox protein hhex	15687261	Heart induction by Wnt antagonists depends on the homeodomain transcription factor Hex.

P05374	PEM1_YEAST	Phosphatidylethanolamine N-methyltransferase	2445736	Yeast phosphatidylethanolamine methylation pathway. Cloning and characterization of two distinct methyltransferase genes.

O74473	CDC11_SCHPO	Septation initiation network scaffold protein cdc11	15062098	Sid4p-Cdc11p assembles the septation initiation network and its regulators at the S. pombe SPB.

Q9UJW0	DCTN4_HUMAN	Dynactin subunit 4	10671518	A dynactin subunit with a highly conserved cysteine-rich motif interacts directly with Arp1.

Q9Y5L5	LENEP_HUMAN	Lens epithelial cell protein LEP503	10655141	A novel lens epithelium gene, LEP503, is highly conserved in different vertebrate species and is developmentally regulated in postnatal rat lens.

Q9FLP0	MA651_ARATH	65-kDa microtubule-associated protein 1	15469496	Molecular dissection of plant cytokinesis and phragmoplast structure: a survey of GFP-tagged proteins.

Q9WVS9	CLOCK_RAT	Circadian locomoter output cycles protein kaput	10095082	Phase-dependent induction by light of rat Clock gene expression in the suprachiasmatic nucleus.

Q6ZXA0	SIA8A_XENLA	Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase	17333390	Molecular cloning and expression of alpha2,8-sialyltransferase (ST8Sia I, GD3 Synthase) in Xenopus.

Q9VFG8	KIBRA_DROME	Protein kibra	20159598	Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded.

P54970	ILL2_ARATH	IAA-amino acid hydrolase ILR1-like 2	11923288	Characterization of a family of IAA-amino acid conjugate hydrolases from Arabidopsis.

Q00534	CDK6_HUMAN	Cell division protein kinase 6	9751050	Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a.

P47055	LOH1_YEAST	Protein LOH1	18562670	A genetic screen for increased loss of heterozygosity in Saccharomyces cerevisiae.

Q01974	ROR2_HUMAN	Tyrosine-protein kinase transmembrane receptor ROR2	1334494	A novel family of cell surface receptors with tyrosine kinase-like domain.

Q8C3J5	DOCK2_MOUSE	Dedicator of cytokinesis protein 2	11518968	Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration.

P97562	ACOX2_RAT	Peroxisomal acyl-coenzyme A oxidase 2	8947475	Molecular cloning and further characterization of rat peroxisomal trihydroxycoprostanoyl-CoA oxidase.

Q9LKI5	XPF_ARATH	DNA repair endonuclease UVH1	11027708	The Arabidopsis UVH1 gene is a homolog of the yeast repair endonuclease RAD1.

P22561	WT1_MOUSE	Wilms tumor protein homolog	14681305	The Wilms' tumour protein (WT1) shuttles between nucleus and cytoplasm and is present in functional polysomes.

O14188	RNG2_SCHPO	Ras GTPase-activating-like protein rng2	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

Q9NZU5	LMCD1_HUMAN	LIM and cysteine-rich domains protein 1	20026769	LIM and cysteine-rich domains 1 regulates cardiac hypertrophy by targeting calcineurin/nuclear factor of activated T cells signaling.

Q99728	BARD1_HUMAN	BRCA1-associated RING domain protein 1	20351172	The UBXN1 protein associates with autoubiquitinated forms of the BRCA1 tumor suppressor and inhibits its enzymatic function.

Q14114	LRP8_HUMAN	Low-density lipoprotein receptor-related protein 8	11152697	Identification of a novel exon in apolipoprotein E receptor 2 leading to alternatively spliced mRNAs found in cells of the vascular wall but not in neuronal tissue.

Q8JGN5	BI51A_XENLA	Baculoviral IAP repeat-containing protein 5.1-A	12221116	Aurora B kinase exists in a complex with survivin and INCENP and its kinase activity is stimulated by survivin binding and phosphorylation.

P40046	VTC1_YEAST	Vacuolar transporter chaperone 1	12584253	Role of the Vtc proteins in V-ATPase stability and membrane trafficking.

Q9NYB0	TE2IP_HUMAN	Telomeric repeat-binding factor 2-interacting protein 1	10850490	Identification of human RAP1: implications for telomere evolution.

Q09274	UN105_CAEEL	Degenerin-like protein unc-105	9655510	The nematode degenerin UNC-105 forms ion channels that are activated by degeneration- or hypercontraction-causing mutations.

O35488	S27A2_MOUSE	Very long-chain acyl-CoA synthetase	9671728	A family of fatty acid transporters conserved from mycobacterium to man.

Q9M6E9	AGGL_ABRPR	Agglutinin-1	15474989	Immunomodulatory role of native and heat denatured agglutinin from Abrus precatorius.

P52657	T2AG_HUMAN	Transcription initiation factor IIA subunit 2	7958900	Reconstitution of human TFIIA activity from recombinant polypeptides: a role in TFIID-mediated transcription.

P38823	DMA1_YEAST	E3 ubiquitin-protein ligase DMA1	18202552	Yeast Chfr homologs retard cell cycle at G1 and G2/M via Ubc4 and Ubc13/Mms2-dependent ubiquitination.

P78317	RNF4_HUMAN	E3 ubiquitin ligase RNF4	20212317	The SUMO protease SENP6 is essential for inner kinetochore assembly.

O96621	ARP2_DICDI	Actin-related protein 2	17553489	Mutants in the Dictyostelium Arp2/3 complex and chemoattractant- induced actin polymerization.

P25976	UBF1_MOUSE	Nucleolar transcription factor 1	20168301	Chromatin association and regulation of rDNA transcription by the Ras-family protein RasL11a.

Q84JT6	MSRB9_ARATH	Peptide methionine sulfoxide reductase B9	17031545	Plant methionine sulfoxide reductase A and B multigenic families.

Q08227	INP54_YEAST	Inositol-1,4,5-trisphosphate 5-phosphatase 4	11116155	The yeast inositol polyphosphate 5-phosphatase Inp54p localizes to the endoplasmic reticulum via a C-terminal hydrophobic anchoring tail: regulation of secretion from the endoplasmic reticulum.

P83307	TE1JA_RANJA	Temporin-1Ja	11835990	Antimicrobial peptides with atypical structural features from the skin of the Japanese brown frog Rana japonica.

Q9UJX5	APC4_HUMAN	Anaphase-promoting complex subunit 4	16364912	Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C.

Q5XPJ9	SCAR2_ARATH	Protein SCAR2	15659634	DISTORTED3/SCAR2 is a putative Arabidopsis WAVE complex subunit that activates the Arp2/3 complex and is required for epidermal morphogenesis.

Q9W0Y6	PAIN_DROME	Transient receptor potential cation channel protein painless	12705873	painless, a Drosophila gene essential for nociception.

O42898	COMT1_SCHPO	Probable catechol O-methyltransferase 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NQB0	TF7L2_HUMAN	Transcription factor 7-like 2	16714285	NARF, an nemo-like kinase (NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF).

P36017	VPS21_YEAST	Vacuolar protein sorting-associated protein 21	10756108	High-resolution crystal structure of S. cerevisiae Ypt51(DeltaC15)- GppNHp, a small GTP-binding protein involved in regulation of endocytosis.

O94290	IST3_SCHPO	U2 snRNP component ist3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P07702	LYS2_YEAST	L-aminoadipate-semialdehyde dehydrogenase	10320345	Lysine biosynthesis in Saccharomyces cerevisiae: mechanism of alpha- aminoadipate reductase (Lys2) involves posttranslational phosphopantetheinylation by Lys5.

Q9VSL7	FOI_DROME	Zinc transporter foi	15464587	The Drosophila transmembrane protein Fear-of-intimacy controls glial cell migration.

O95278	EPM2A_HUMAN	Laforin	17908927	A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease.

Q9GZP9	DERL2_HUMAN	Derlin-2	15215855	A membrane protein required for dislocation of misfolded proteins from the ER.

P32585	MED18_YEAST	Mediator of RNA polymerase II transcription subunit 18	16885025	Head module control of mediator interactions.

Q02936	HH_DROME	Protein hedgehog	9335337	Crystal structure of a Hedgehog autoprocessing domain: homology between Hedgehog and self-splicing proteins.

P83524	FER_PHYAF	Ferredoxin	9862138	Amino acid sequence of ferredoxin from Physalis alkekengi var. francheti.

Q86Z02	HIPK1_HUMAN	Homeodomain-interacting protein kinase 1	12702766	Characterization of cells and gene-targeted mice deficient for the p53-binding kinase homeodomain-interacting protein kinase 1 (HIPK1).

Q8IY57	YAF2_HUMAN	YY1-associated factor 2	12706874	Yaf2 inhibits Myc biological function.

Q0WQ57	AUXI2_ARATH	Auxilin-related protein 2	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

P78318	IGBP1_HUMAN	Immunoglobulin-binding protein 1	9647778	Alpha 4 associates with protein phosphatases 2A, 4, and 6.

Q94469	G3P_DICDI	Glyceraldehyde-3-phosphate dehydrogenase	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P32799	COX13_YEAST	Cytochrome c oxidase subunit 6A, mitochondrial	8395517	Subunit VIa of yeast cytochrome c oxidase is not necessary for assembly of the enzyme complex but modulates the enzyme activity. Isolation and characterization of the nuclear-coded gene.

O35295	PURB_MOUSE	Transcriptional activator protein Pur-beta	10318844	Molecular interactions between single-stranded DNA-binding proteins associated with an essential MCAT element in the mouse smooth muscle alpha-actin promoter.

O94805	ACL6B_HUMAN	Actin-like protein 6B	10380635	Two isoforms of a human actin-related protein show nuclear localization and mutually selective expression between brain and other tissues.

Q99640	PMYT1_HUMAN	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	12738781	Identification of a consensus motif for Plk (Polo-like kinase) phosphorylation reveals Myt1 as a Plk1 substrate.

P40024	ARB1_YEAST	ABC transporter ATP-binding protein ARB1	16260602	The novel ATP-binding cassette protein ARB1 is a shuttling factor that stimulates 40S and 60S ribosome biogenesis.

Q61626	GRIK5_MOUSE	Glutamate receptor, ionotropic kainate 5	1310861	Primary structure and expression of the gamma 2 subunit of the glutamate receptor channel selective for kainate.

Q7Z9H9	YLE3_SCHPO	Uncharacterized protein C1093.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q15233	NONO_HUMAN	Non-POU domain-containing octamer-binding protein	9360842	Loss of expression of a 55 kDa nuclear protein (nmt55) in estrogen receptor-negative human breast cancer.

P51639	HMDH_RAT	3-hydroxy-3-methylglutaryl-coenzyme A reductase	4019513	Functional size of rat hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase as determined by radiation inactivation.

Q22271	UNC58_CAEEL	Uncoordinated protein 58	8582640	Analysis of dominant mutations affecting muscle excitation in Caenorhabditis elegans.

Q12507	SFG1_YEAST	Superficial pseudohyphal growth protein 1	16289536	Enhancement of superficial pseudohyphal growth by overexpression of the SFG1 gene in yeast Saccharomyces cerevisiae.

Q8BZQ2	CRLD2_MOUSE	Cysteine-rich secretory protein LCCL domain-containing 2	18757743	Transcriptome-based systematic identification of extracellular matrix proteins.

P40533	TED1_YEAST	Protein TED1	17989219	Identification of yeast proteins necessary for cell-surface function of a potassium channel.

Q15291	RBBP5_HUMAN	Retinoblastoma-binding protein 5	15960975	Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

B7ZQA9	P5F12_XENLA	POU domain, class 5, transcription factor 1.2	1732736	Sequential expression of multiple POU proteins during amphibian early development.

Q8VD98	KLRBF_MOUSE	Killer cell lectin-like receptor subfamily B member 1F	15963483	C-type lectin OCILRP2/Clr-g and its ligand NKRP1f costimulate T cell proliferation and IL-2 production.

Q15035	TRAM2_HUMAN	Translocating chain-associated membrane protein 2	14749390	TRAM2 protein interacts with endoplasmic reticulum Ca2+ pump Serca2b and is necessary for collagen type I synthesis.

Q06604	BSP1_YEAST	Protein BSP1	12606027	Bsp1p/Ypr171p is an adapter that directly links some synaptojanin family members to the cortical actin cytoskeleton in yeast.

Q05533	INM2_YEAST	Inositol monophosphatase 2	10096091	The yeast inositol monophosphatase is a lithium- and sodium-sensitive enzyme encoded by a non-essential gene pair.

P07664	SRYD_DROME	Serendipity locus protein delta	2081456	The closely related Drosophila sry beta and sry delta zinc finger proteins show differential embryonic expression and distinct patterns of binding sites on polytene chromosomes.

Q9ZVD0	SRRT_ARATH	Serrate RNA effector molecule	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

Q9LIG6	NIFU4_ARATH	NifU-like protein 4, mitochondrial	12553879	Iron-sulphur cluster assembly in plants: distinct NFU proteins in mitochondria and plastids from Arabidopsis thaliana.

Q3EDL4	Y1154_ARATH	Probable serine/threonine-protein kinase At1g01540	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q08491	SKI7_YEAST	Superkiller protein 7	11910110	Exosome-mediated recognition and degradation of mRNAs lacking a termination codon.

P48009	SPN4_SCHPO	Septin homolog spn4	15385632	Requirements of fission yeast septins for complex formation, localization, and function.

Q94465	GCH1_DICDI	GTP cyclohydrolase 1	8870645	Molecular cloning of a cDNA coding for GTP cyclohydrolase I from Dictyostelium discoideum.

P80703	APL3_GALME	Apolipophorin-3	17194500	Purification and characterization of eight peptides from Galleria mellonella immune hemolymph.

Q06078	UTP21_YEAST	U3 small nucleolar RNA-associated protein 21	14562095	Global analysis of protein localization in budding yeast.

P23724	PSB1_YEAST	Proteasome component C5	9087403	Structure of 20S proteasome from yeast at 2.4-A resolution.

O59727	YHX7_SCHPO	UPF0368 protein C3E7.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P11349	NARH_ECOLI	Respiratory nitrate reductase 1 beta chain	14725769	Architecture of NarGH reveals a structural classification of Mo- bisMGD enzymes.

Q9QZA0	CAH5B_MOUSE	Carbonic anhydrase 5B, mitochondrial	10677517	Mitochondrial carbonic anhydrase CA VB: differences in tissue distribution and pattern of evolution from those of CA VA suggest distinct physiological roles.

P53705	BUD4_CANAL	Bud site selection protein BUD4	16178371	Intracellular trafficking of fluorescently tagged proteins associated with pathogenesis in Candida albicans.

Q9ZNV9	AHP1_ARATH	Histidine-containing phosphotransfer protein 1	9804162	Characterization of genes for two-component phosphorelay mediators with a single HPt domain in Arabidopsis thaliana.

P51680	CCR4_MOUSE	C-C chemokine receptor type 4	10811868	A key role for CC chemokine receptor 4 in lipopolysaccharide-induced endotoxic shock.

O95498	VNN2_HUMAN	Vascular non-inflammatory molecule 2	9790769	Two human genes related to murine vanin-1 are located on the long arm of human chromosome 6.

Q09472	EP300_HUMAN	Histone acetyltransferase p300	12750254	p29ING4 and p28ING5 bind to p53 and p300, and enhance p53 activity.

P38398	BRCA1_HUMAN	Breast cancer type 1 susceptibility protein	19261749	NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control.

P0A855	TOLB_ECOLI	Protein tolB	7929011	Maturation and localization of the TolB protein required for colicin import.

P36161	NU133_YEAST	Nucleoporin NUP133	11823431	Modular self-assembly of a Y-shaped multiprotein complex from seven nucleoporins.

P19334	TRP_DROME	Transient receptor potential protein	9010208	Requirement for the PDZ domain protein, INAD, for localization of the TRP store-operated channel to a signaling complex.

Q01196	RUNX1_HUMAN	Runt-related transcription factor 1	14970218	Isoforms of the Ets transcription factor NERF/ELF-2 physically interact with AML1 and mediate opposing effects on AML1-mediated transcription of the B cell-specific blk gene.

P41277	GPP1_YEAST	(DL)-glycerol-3-phosphatase 1	8662716	Purification and characterization of two isoenzymes of DL-glycerol-3- phosphatase from Saccharomyces cerevisiae. Identification of the corresponding GPP1 and GPP2 genes and evidence for osmotic regulation of Gpp2p expression by the osmosensing mitogen-activated protein kinase signal transduction pathway.

Q61315	APC_MOUSE	Adenomatous polyposis coli protein	16611247	Human scribble, a novel tumor suppressor identified as a target of high-risk HPV E6 for ubiquitin-mediated degradation, interacts with adenomatous polyposis coli.

P46020	KPB1_HUMAN	Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform	8226841	The multiphosphorylation domain of the phosphorylase kinase alpha M and alpha L subunits is a hotspot of differential mRNA processing and of molecular evolution.

Q8S2T0	GRIP_ARATH	Protein GRIP	16236155	An Arabidopsis GRIP domain protein locates to the trans-Golgi and binds the small GTPase ARL1.

Q15542	TAF5_HUMAN	Transcription initiation factor TFIID subunit 5	9045704	Specific interactions and potential functions of human TAFII100.

Q9XWD6	CED1_CAEEL	Cell death abnormality protein 1	18606143	Unfolded protein response genes regulated by CED-1 are required for Caenorhabditis elegans innate immunity.

P59996	PCSK9_RAT	Proprotein convertase subtilisin/kexin type 9	12552133	The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation.

Q15633	TRBP2_HUMAN	RISC-loading complex subunit TARBP2	16142218	TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing.

Q2MHQ9	TIFA_XENLA	TRAF-interacting protein with FHA domain-containing protein A	16023795	Identification and characterization of Xenopus laevis homologs of mammalian TRAF6 and its binding protein TIFA.

Q9Z1L3	DEDD_MOUSE	Death effector domain-containing protein	9774341	DEDD, a novel death effector domain-containing protein, targeted to the nucleolus.

P29674	LHX1_XENLA	LIM/homeobox protein Lhx1	10926781	Xlim-1 and LIM domain binding protein 1 cooperate with various transcription factors in the regulation of the goosecoid promoter.

Q9S7D1	DGDG1_ARATH	Digalactosyldiacylglycerol synthase 1, chloroplastic	10381884	Arabidopsis galactolipid biosynthesis and lipid trafficking mediated by DGD1.

O77384	LRR4_PLAF7	LRR domain-containing protein PFC0760c	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

Q9Y239	NOD1_HUMAN	Nucleotide-binding oligomerization domain-containing protein 1	19043560	GEF-H1 mediated control of NOD1 dependent NF-kappaB activation by Shigella effectors.

Q12355	PST1_YEAST	Cell wall mannoprotein PST1	15583168	PST1 and ECM33 encode two yeast cell surface GPI proteins important for cell wall integrity.

P32121	ARRB2_HUMAN	Beta-arrestin-2	10644702	beta-arrestin differentially regulates the chemokine receptor CXCR4- mediated signaling and receptor internalization, and this implicates multiple interaction sites between beta-arrestin and CXCR4.

P39720	OAF1_YEAST	Oleate-activated transcription factor 1	8662598	Purification, identification, and properties of a Saccharomyces cerevisiae oleate-activated upstream activating sequence-binding protein that is involved in the activation of POX1.

Q9Y821	MED4_SCHPO	Mediator of RNA polymerase II transcription subunit 4	10625684	Purification and characterization of RNA polymerase II holoenzyme from Schizosaccharomyces pombe.

Q95YL5	PEFA_DICDI	Penta-EF hand domain-containing protein 1	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P08539	GPA1_YEAST	Guanine nucleotide-binding protein alpha-1 subunit	1900495	Mutations in the guanine nucleotide-binding domains of a yeast G alpha protein confer a constitutive or uninducible state to the pheromone response pathway.

Q9USV1	SFR1_SCHPO	Swi5-dependent recombination DNA repair protein 1	14663140	Two different Swi5-containing protein complexes are involved in mating-type switching and recombination repair in fission yeast.

Q03164	MLL1_HUMAN	Histone-lysine N-methyltransferase MLL	15960975	Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

P10505	APC3_SCHPO	Anaphase-promoting complex subunit 3	9264466	Distinct subunit functions and cell cycle regulated phosphorylation of 20S APC/cyclosome required for anaphase in fission yeast.

Q9D1L0	CHCH2_MOUSE	Coiled-coil-helix-coiled-coil-helix domain-containing protein 2, mitochondrial	14651853	Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.

Q92900	RENT1_HUMAN	Regulator of nonsense transcripts 1	19150429	Human proline-rich nuclear receptor coregulatory protein 2 mediates an interaction between mRNA surveillance machinery and decapping complex.

P09496	CLCA_HUMAN	Clathrin light chain A	3267234	Structure of human clathrin light chains. Conservation of light chain polymorphism in three mammalian species.

P40186	PCL7_YEAST	PHO85 cyclin-7	12407105	Pho85 phosphorylates the Glc7 protein phosphatase regulator Glc8 in vivo.

P40098	FMP10_YEAST	Uncharacterized mitochondrial membrane protein FMP10	14562095	Global analysis of protein localization in budding yeast.

P83835	CYO12_VIOAR	Varv peptide E	14987049	Cytotoxic cyclotides from Viola tricolor.

P13563	HAS1_XENLA	Hyaluronan synthase 1	9442026	Characterization and molecular evolution of a vertebrate hyaluronan synthase gene family.

Q01134	CHKA_RAT	Choline kinase alpha	1577786	Molecular cloning, characterization, and expression in Escherichia coli of a cDNA encoding mammalian choline kinase.

Q9Y3A5	SBDS_HUMAN	Ribosome maturation protein SBDS	17643419	The Shwachman-Bodian-Diamond syndrome associated protein interacts with HsNip7 and its down-regulation affects gene expression at the transcriptional and translational levels.

Q99638	RAD9A_HUMAN	Cell cycle checkpoint control protein RAD9A	11971963	c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage.

Q800K6	TOB1A_XENLA	DNA topoisomerase 2-binding protein 1-A	16923121	The phosphorylated C-terminal domain of Xenopus Cut5 directly mediates ATR-dependent activation of Chk1.

P40917	YAP4_YEAST	AP-1-like transcription factor YAP4	9372930	Yap, a novel family of eight bZIP proteins in Saccharomyces cerevisiae with distinct biological functions.

Q7TS99	HELT_MOUSE	Hairy and enhancer of split-related protein HELT	16968817	Megane/Heslike is required for normal GABAergic differentiation in the mouse superior colliculus.

P35343	CXCR2_MOUSE	C-X-C chemokine receptor type 2	14764687	IL-10-conditioned dendritic cells, decommissioned for recruitment of adaptive immunity, elicit innate inflammatory gene products in response to danger signals.

P34949	MPI_HUMAN	Mannose-6-phosphate isomerase	8307007	Purification, cDNA cloning and heterologous expression of human phosphomannose isomerase.

Q60935	NAR1_MOUSE	GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1	9052744	Molecular cloning of a functional murine arginine-specific mono-ADP- ribosyltransferase and its expression in lymphoid cells.

Q07457	BRE1_YEAST	E3 ubiquitin-protein ligase BRE1	12535538	A conserved RING finger protein required for histone H2B monoubiquitination and cell size control.

P38246	ECM8_YEAST	Protein ECM8	9335584	Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae.

P28827	PTPRM_HUMAN	Receptor-type tyrosine-protein phosphatase mu	1655529	Cloning, expression and chromosomal localization of a new putative receptor-like protein tyrosine phosphatase.

Q96F46	I17RA_HUMAN	Interleukin-17 receptor A	9367539	Molecular characterization of the human interleukin (Il)-17 receptor.

P53244	ART5_YEAST	Arrestin-related trafficking adapter 5	18976803	Arrestin-related ubiquitin-ligase adaptors regulate endocytosis and protein turnover at the cell surface.

Q92451	AGAL3_TRIRE	Alpha-galactosidase 3	8797842	Three alpha-galactosidase genes of Trichoderma reesei cloned by expression in yeast.

O16102	CHD3_DROME	Chromodomain-helicase-DNA-binding protein 3	9326634	Characterization of the CHD family of proteins.

P70700	RPA2_MOUSE	DNA-directed RNA polymerase I subunit RPA2	8921381	Molecular cloning of RPA2, the gene encoding the second largest subunit of mouse RNA polymerase I.

P70429	EVL_MOUSE	Ena/VASP-like protein	10945997	cAMP-dependent protein kinase phosphorylation of EVL, a Mena/VASP relative, regulates its interaction with actin and SH3 domains.

Q8R2R1	POMT1_MOUSE	Protein O-mannosyl-transferase 1	15383666	Targeted disruption of the Walker-Warburg syndrome gene Pomt1 in mouse results in embryonic lethality.

O60858	TRI13_HUMAN	E3 ubiquitin-protein ligase TRIM13	17314412	The RBCC gene RFP2 (Leu5) encodes a novel transmembrane E3 ubiquitin ligase involved in ERAD.

P09001	RM03_HUMAN	39S ribosomal protein L3, mitochondrial	2891103	Cloning and characterization of a human ribosomal protein gene with enhanced expression in fetal and neoplastic cells.

Q9WUB4	DCTN6_MOUSE	Dynactin subunit 6	10318868	Up-regulation of nuclear and mitochondrial genes in the skeletal muscle of mice lacking the heart/muscle isoform of the adenine nucleotide translocator.

Q9HCE7	SMUF1_HUMAN	E3 ubiquitin-protein ligase SMURF1	10458166	A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation.

P25025	CXCR2_HUMAN	C-X-C chemokine receptor type 2	9079638	Ligand-induced desensitization of the human CXC chemokine receptor-2 is modulated by multiple serine residues in the carboxyl-terminal domain of the receptor.

P36511	UDB15_RAT	UDP-glucuronosyltransferase 2B15	7574722	Cloning and expression of a rat liver phenobarbital-inducible UDP- glucuronosyltransferase (2B12) with specificity for monoterpenoid alcohols.

Q04602	VBA4_YEAST	Vacuolar basic amino acid transporter 4	14562095	Global analysis of protein localization in budding yeast.

P09629	HXB7_HUMAN	Homeobox protein Hox-B7	2885844	Two human homeobox genes, c1 and c8: structure analysis and expression in embryonic development.

P38264	PHO88_YEAST	Inorganic phosphate transport protein PHO88	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q7XAD0	HSY1_SOLLC	Hydroxyproline-rich systemin	12748180	Systemic signaling in tomato plants for defense against herbivores: isolation and characterization of three novel defense-signaling glycopeptide hormones coded in a single precursor gene.

Q9Y314	NOSIP_HUMAN	Nitric oxide synthase-interacting protein	11149895	NOSIP, a novel modulator of endothelial nitric oxide synthase activity.

P53136	NSA1_YEAST	Ribosome biogenesis protein NSA1	14562095	Global analysis of protein localization in budding yeast.

O22042	M3K3_ARATH	Mitogen-activated protein kinase kinase kinase 3	20215588	Arabidopsis homologs of nucleus- and phragmoplast-localized kinase 2 and 3 and mitogen-activated protein kinase 4 are essential for microtubule organization.

P38432	COIL_HUMAN	Coilin	7971277	Structure, expression and chromosomal localization of human p80- coilin gene.

Q7M6Z0	R4RL2_MOUSE	Reticulon-4 receptor-like 2	14664809	Two novel mammalian nogo receptor homologs differentially expressed in the central and peripheral nervous systems.

Q99758	ABCA3_HUMAN	ATP-binding cassette sub-family A member 3	9027511	The cloning of a human ABC gene (ABC3) mapping to chromosome 16p13.3.

Q9UQ88	CD11A_HUMAN	Cell division protein kinase 11A	10882096	Identification and characterization of a novel cell cycle-regulated internal ribosome entry site.

P47133	EMC2_YEAST	ER membrane protein complex subunit 2	14562095	Global analysis of protein localization in budding yeast.

Q08951	AP3D_YEAST	AP-3 complex subunit delta	10559961	Formation of AP-3 transport intermediates requires Vps41 function.

A6NFY7	SDHF1_HUMAN	Succinate dehydrogenase assembly factor 1, mitochondrial	19465911	SDHAF1, encoding a LYR complex-II specific assembly factor, is mutated in SDH-defective infantile leukoencephalopathy.

Q05701	LPLC3_RAT	Long palate, lung and nasal epithelium carcinoma-associated protein 3	1915264	Novel genes for potential ligand-binding proteins in subregions of the olfactory mucosa.

Q12285	MDY2_YEAST	Ubiquitin-like protein MDY2	20106980	Crystal structure of Get4-Get5 complex and its interactions with Sgt2, Get3, and Ydj1.

P45975	SUV39_DROME	Histone-lysine N-methyltransferase Su(var)3-9	11867540	Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing.

P40099	FTHC_YEAST	5-formyltetrahydrofolate cyclo-ligase	11923304	Cloning and characterization of methenyltetrahydrofolate synthetase from Saccharomyces cerevisiae.

O80860	FTSH2_ARATH	ATP-dependent zinc metalloprotease FTSH 2, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q9UKA1	FBXL5_HUMAN	F-box/LRR-repeat protein 5	19762597	An E3 ligase possessing an iron responsive hemerythrin domain is a regulator of iron homeostasis.

P09052	VASA1_DROME	ATP-dependent RNA helicase vasa, isoform A	10678180	VASA mediates translation through interaction with a Drosophila yIF2 homolog.

P08238	HS90B_HUMAN	Heat shock protein HSP 90-beta	2768249	Nucleotide sequence and regulation of a human 90-kDa heat shock protein gene.

P82322	UT103_PEA	Unknown protein from spot 103 of 2D-PAGE of thylakoid	10715320	Proteomics of the chloroplast: systematic identification and targeting analysis of lumenal and peripheral thylakoid proteins.

O74791	GRN1_SCHPO	GTPase grn1	16251348	The homologous putative GTPases Grn1p from fission yeast and the human GNL3L are required for growth and play a role in processing of nucleolar pre-rRNA.

O09178	AMPD3_RAT	AMP deaminase 3	9291127	Regulation of rat AMP deaminase 3 (isoform C) by development and skeletal muscle fibre type.

P46282	IL12B_BOVIN	Interleukin-12 subunit beta	7727547	Enzymatic amplification and molecular cloning of cDNA encoding the small and large subunits of bovine interleukin 12.

P42284	LOLA2_DROME	Longitudinals lacking protein, isoforms H/M/V	12538650	A developmentally regulated splice variant from the complex lola locus encoding multiple different zinc finger domain proteins interacts with the chromosomal kinase JIL-1.

Q01163	RT23_YEAST	37S ribosomal protein S23, mitochondrial	11278769	Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues.

Q92207	HOG1_CANAL	Mitogen-activated protein kinase HOG1	16467475	The Cek1 and Hog1 mitogen-activated protein kinases play complementary roles in cell wall biogenesis and chlamydospore formation in the fungal pathogen Candida albicans.

P0AAN9	IRAP_ECOLI	Anti-adapter protein iraP	17640895	ppGpp regulation of RpoS degradation via anti-adaptor protein IraP.

Q00959	NMDE1_RAT	Glutamate [NMDA] receptor subunit epsilon-1	8428958	Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits.

Q00987	MDM2_HUMAN	E3 ubiquitin-protein ligase Mdm2	20173098	RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage.

P18418	CALR_RAT	Calreticulin	8453984	An endoplasmic reticulum protein, calreticulin, is transported into the acrosome of rat sperm.

Q24256	BARH2_DROME	Homeobox protein B-H2	1346120	Dual Bar homeo box genes of Drosophila required in two photoreceptor cells, R1 and R6, and primary pigment cells for normal eye development.

Q8GYT9	SIS3_ARATH	E3 ubiquitin-protein ligase SIS3	20147494	SUGAR-INSENSITIVE3, a RING E3 ligase, is a new player in plant sugar response.

Q6UVM4	KCNT2_RAT	Potassium channel subfamily T member 2	14684870	Slick (Slo2.1), a rapidly-gating sodium-activated potassium channel inhibited by ATP.

P27694	RFA1_HUMAN	Replication protein A 70 kDa DNA-binding subunit	16135809	Sumoylation of the novel protein hRIPbeta is involved in replication protein A deposition in PML nuclear bodies.

P38786	RPP1_YEAST	Ribonuclease P/MRP protein subunit RPP1	9353260	ERRATUM
Q96RP7	G3ST4_HUMAN	Galactose-3-O-sulfotransferase 4	11333265	Molecular cloning and characterization of a novel human galactose 3- O-sulfotransferase that transfers sulfate to Galbeta1->3GalNAc residue in O-glycans.

O35054	CLD4_MOUSE	Claudin-4	10601346	Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins.

Q6P788	ATF5_RAT	Cyclic AMP-dependent transcription factor ATF-5	12805299	Regulated expression of ATF5 is required for the progression of neural progenitor cells to neurons.

Q708W1	FXJ1B_XENLA	Forkhead box protein J1-B	15656969	Of fox and frogs: fox (fork head/winged helix) transcription factors in Xenopus development.

P62804	H4_RAT	Histone H4	1706721	Protein-DNA interactions within the rat histone H4t promoter.

Q01097	NMDE2_MOUSE	Glutamate [NMDA] receptor subunit epsilon-2	1377365	Molecular diversity of the NMDA receptor channel.

Q2PW47	MED24_DANRE	Mediator of RNA polymerase II transcription subunit 24	16396911	Lessen encodes a zebrafish trap100 required for enteric nervous system development.

P53140	RMD9_YEAST	Protein RMD9, mitochondrial	17194787	Rmd9p controls the processing/stability of mitochondrial mRNAs and its overexpression compensates for a partial deficiency of oxa1p in Saccharomyces cerevisiae.

P22579	SIN3_YEAST	Transcriptional regulatory protein SIN3	9710596	Targeted recruitment of the Sin3-Rpd3 histone deacetylase complex generates a highly localized domain of repressed chromatin in vivo.

Q8TDF6	GRP4_HUMAN	RAS guanyl-releasing protein 4	11880369	RasGRP4 is a novel Ras activator isolated from acute myeloid leukemia.

Q9N359	CSN4_CAEEL	COP9 signalosome complex subunit 4	12781129	Neddylation and deneddylation of CUL-3 is required to target MEI- 1/katanin for degradation at the meiosis-to-mitosis transition in C. elegans.

P15144	AMPN_HUMAN	Aminopeptidase N	1350662	Human aminopeptidase N is a receptor for human coronavirus 229E.

P32881	IFNA8_HUMAN	Interferon alpha-8	6163083	The structure of eight distinct cloned human leukocyte interferon cDNAs.

Q52KL1	FITM2_DANRE	Fat storage-inducing transmembrane protein 2	18160536	Evolutionarily conserved gene family important for fat storage.

O64425	RMA1_ARATH	E3 ubiquitin-protein ligase RMA1	19224217	Characterization of three Arabidopsis homologs of human RING membrane anchor E3 ubiquitin ligase.

Q04368	CSI1_YEAST	Cop9 signalosome-interactor 1	12446563	COP9 signalosome components play a role in the mating pheromone response of S. cerevisiae.

Q9SYG7	AL7B4_ARATH	Aldehyde dehydrogenase family 7 member B4	15830124	Detailed expression analysis of selected genes of the aldehyde dehydrogenase(ALDH) gene superfamily in Arabidopsis thaliana.

Q16617	NKG7_HUMAN	Protein NKG7	8458737	Characterization of a novel gene (NKG7) on human chromosome 19 that is expressed in natural killer cells and T cells.

P49957	TRM9_YEAST	tRNA (uracil-5-)-methyltransferase TRM9	14562095	Global analysis of protein localization in budding yeast.

P53178	ALG13_YEAST	UDP-N-acetylglucosamine transferase subunit ALG13	15615718	Two proteins homologous to the N- and C-terminal domains of the bacterial glycosyltransferase Murg are required for the second step of dolichyl-linked oligosaccharide synthesis in Saccharomyces cerevisiae.

Q9V576	WUN_DROME	Putative phosphatidate phosphatase	12856002	Fly and mammalian lipid phosphate phosphatase isoforms differ in activity both in vitro and in vivo.

P38286	MKAR_YEAST	3-ketoacyl-CoA reductase	12087109	The Saccharomyces cerevisiae YBR159w gene encodes the 3-ketoreductase of the microsomal fatty acid elongase.

Q9H081	MIS12_HUMAN	Protein MIS12 homolog	12515822	Human centromere chromatin protein hMis12, essential for equal segregation, is independent of CENP-A loading pathway.

O04292	ATBH9_ARATH	Homeobox-leucine zipper protein ATHB-9	15598805	Class III homeodomain-leucine zipper gene family members have overlapping, antagonistic, and distinct roles in Arabidopsis development.

O43181	NDUS4_HUMAN	NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial	9463323	Demonstration of a new pathogenic mutation in human complex I deficiency: a 5-bp duplication in the nuclear gene encoding the 18-kD (AQDQ) subunit.

Q8R5K2	UBP33_MOUSE	Ubiquitin carboxyl-terminal hydrolase 33	19706539	Deubiquitinating enzyme USP33/VDU1 is required for Slit signaling in inhibiting breast cancer cell migration.

Q99218	AMELY_HUMAN	Amelogenin, Y isoform	1734713	The human enamel protein gene amelogenin is expressed from both the X and the Y chromosomes.

Q9Y226	S22AD_HUMAN	Solute carrier family 22 member 13	10072596	Molecular cloning, mapping, and characterization of two novel human genes, ORCTL3 and ORCTL4, bearing homology to organic-cation transporters.

Q9TYU5	TIP60_CAEEL	Histone acetyltransferase Tip60 homolog	15068795	A new class of C. elegans synMuv genes implicates a Tip60/NuA4-like HAT complex as a negative regulator of Ras signaling.

Q9FHM4	MA653_ARATH	65-kDa microtubule-associated protein 3	15469496	Molecular dissection of plant cytokinesis and phragmoplast structure: a survey of GFP-tagged proteins.

Q04206	TF65_HUMAN	Transcription factor p65	15125834	Identification of beta-arrestin2 as a G protein-coupled receptor- stimulated regulator of NF-kappaB pathways.

P53674	CRBB1_HUMAN	Beta-crystallin B1	8626774	The sequence of human betaB1-crystallin cDNA allows mass spectrometric detection of betaB1 protein missing portions of its N- terminal extension.

Q04952	FKS3_YEAST	1,3-beta-glucan synthase component FKS3	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q9R0H2	MUCEN_MOUSE	Endomucin	9864158	Biochemical characterization and molecular cloning of a novel endothelial-specific sialomucin.

Q24211	STNA_DROME	Protein stoned-A	9822725	A product of the Drosophila stoned locus regulates neurotransmitter release.

Q12284	ERV2_YEAST	FAD-linked sulfhydryl oxidase ERV2	11584268	A flavoprotein oxidase defines a new endoplasmic reticulum pathway for biosynthetic disulphide bond formation.

O43447	PPIH_HUMAN	Peptidyl-prolyl cis-trans isomerase H	9570313	The 20kD protein of human [U4/U6.U5] tri-snRNPs is a novel cyclophilin that forms a complex with the U4/U6-specific 60kD and 90kD proteins.

O75493	CAH11_HUMAN	Carbonic anhydrase-related protein 11	9878252	Evolutionarily conserved, 'acatalytic' carbonic anhydrase-related protein XI contains a sequence motif present in the neuropeptide sauvagine: the human CA-RP XI gene (CA11) is embedded between the secretor gene cluster and the DBP gene at 19q13.3.

P06730	IF4E_HUMAN	Eukaryotic translation initiation factor 4E	9878069	Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E.

Q20054	MAB21_CAEEL	Protein male abnormal 21	8582275	The mab-21 gene of Caenorhabditis elegans encodes a novel protein required for choice of alternate cell fates.

P21675	TAF1_HUMAN	Transcription initiation factor TFIID subunit 1	15053879	Phosphorylation on Thr-55 by TAF1 mediates degradation of p53: a role for TAF1 in cell G1 progression.

Q7TQN3	WFKN2_MOUSE	WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 2	12595574	Regulation of myostatin in vivo by growth and differentiation factor- associated serum protein-1: a novel protein with protease inhibitor and follistatin domains.

P01607	KV115_HUMAN	Ig kappa chain V-I region Rei	809329	The primary structure of a crystalline monoclonal immunoglobulin kappa-type L-chain, subgroup I (Bence-Jones protein Rei); isolation and characterization of the tryptic peptides; the complete amino acid sequence of the protein; a contribution to the elucidation of the three-dimensional structure of antibodies, in particular their combining site.

P46092	CCR10_HUMAN	C-C chemokine receptor type 10	7851889	Cloning of human genes encoding novel G protein-coupled receptors.

Q15434	RBMS2_HUMAN	RNA-binding motif, single-stranded-interacting protein 2	8041632	SCR: novel human suppresors of cdc2/cdc13 mutants of Schizosaccharomyces pombe harbour motifs for RNA binding proteins.

Q8VZS8	PYL1_ARATH	Abscisic acid receptor PYL1	19407143	Regulators of PP2C phosphatase activity function as abscisic acid sensors.

Q03957	CTK1_YEAST	CTD kinase subunit alpha	9110987	Modulation of RNA polymerase II elongation efficiency by C-terminal heptapeptide repeat domain kinase I.

Q99578	RIT2_HUMAN	GTP-binding protein Rit2	8824319	Rin, a neuron-specific and calmodulin-binding small G-protein, and Rit define a novel subfamily of ras proteins.

Q27GK7	TPR4_ARATH	Topless-related protein 4	16461579	Analysis of the transcription factor WUSCHEL and its functional homologue in Antirrhinum reveals a potential mechanism for their roles in meristem maintenance.

P23219	PGH1_HUMAN	Prostaglandin G/H synthase 1	1907252	Human platelet/erythroleukemia cell prostaglandin G/H synthase: cDNA cloning, expression, and gene chromosomal assignment.

P47111	VPS55_YEAST	Vacuolar protein sorting-associated protein 55	12006663	Yeast Vps55p, a functional homolog of human obesity receptor gene- related protein, is involved in late endosome to vacuole trafficking.

O60613	SEP15_HUMAN	15 kDa selenoprotein	11278576	Association between the 15-kDa selenoprotein and UDP- glucose:glycoprotein glucosyltransferase in the endoplasmic reticulum of mammalian cells.

Q9P4R5	CREC_EMENI	Catabolite repression protein creC	11918805	The WD40-repeat protein CreC interacts with and stabilizes the deubiquitinating enzyme CreB in vivo in Aspergillus nidulans.

Q9FZ45	Y1686_ARATH	Uncharacterized membrane protein At1g16860	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q9EQP5	PRELP_RAT	Prolargin	11007795	The amino-terminal part of PRELP binds to heparin and heparan sulfate.

O74497	YCRA_SCHPO	SPRY domain-containing protein C285.10c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O23052	Y1515_ARATH	Uncharacterized TPR repeat-containing protein At1g05150	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q24141	SGO1_DROME	Shugoshin	9869638	Maintenance of sister-chromatid cohesion at the centromere by the Drosophila MEI-S332 protein.

P67871	CSK2B_MOUSE	Casein kinase II subunit beta	12849985	The protein of a new gene, Tctex4, interacts with protein kinase CK2beta subunit and is highly expressed in mouse testis.

P0AFK9	POTD_ECOLI	Spermidine/putrescine-binding periplasmic protein	1939142	Characteristics of the gene for a spermidine and putrescine transport system that maps at 15 min on the Escherichia coli chromosome.

Q9BQ83	SLX1_HUMAN	Structure-specific endonuclease subunit SLX1	19595721	Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair.

Q04195	SIZ1_YEAST	E3 SUMO-protein ligase SIZ1	11587849	A novel factor required for the SUMO1/Smt3 conjugation of yeast septins.

P49789	FHIT_HUMAN	Bis(5'-adenosyl)-triphosphatase	8598045	The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers.

Q24256	BARH2_DROME	Homeobox protein B-H2	10068639	Bar homeobox genes are latitudinal prepattern genes in the developing Drosophila notum whose expression is regulated by the concerted functions of decapentaplegic and wingless.

P40502	AIM19_YEAST	Altered inheritance of mitochondria protein 19, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q9BUZ4	TRAF4_HUMAN	TNF receptor-associated factor 4	7592751	Presence of a new conserved domain in CART1, a novel member of the tumor necrosis factor receptor-associated protein family, which is expressed in breast carcinoma.

O61491	FLOT1_DROME	Flotillin-1	9573373	Identification, sequence and developmental expression of invertebrate flotillins from Drosophila melanogaster.

Q04217	DHR1_YEAST	Probable ATP-dependent RNA helicase DHR1	10982841	Dhr1p, a putative DEAH-Box RNA helicase, is associated with the box C+D snoRNP U3.

O94320	AATM_SCHPO	Aspartate aminotransferase, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9LK57	PP226_ARATH	Pentatricopeptide repeat-containing protein At3g13160, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P07953	F261_RAT	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	2549541	5' flanking sequence and structure of a gene encoding rat 6- phosphofructo-2-kinase/fructose-2,6-bisphosphatase.

P63041	CPLX1_RAT	Complexin-1	7553862	Complexins: cytosolic proteins that regulate SNAP receptor function.

P11103	PARP1_MOUSE	Poly [ADP-ribose] polymerase 1	11948190	Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1.

Q0MWV8	AURE_AURAU	Aurelin	16890198	Aurelin, a novel antimicrobial peptide from jellyfish Aurelia aurita with structural features of defensins and channel-blocking toxins.

P42845	STB1_YEAST	Protein STB1	12832490	G1 transcription factors are differentially regulated in Saccharomyces cerevisiae by the Swi6-binding protein Stb1.

Q8NI35	INADL_HUMAN	InaD-like protein	18596123	KIBRA modulates directional migration of podocytes.

O74503	UAF30_SCHPO	Upstream activation factor subunit spp27	12490702	Characterization of the fission yeast ribosomal DNA binding factor: components share homology with upstream activating factor and with SWI/SNF subunits.

Q9MAC9	PDRP2_ARATH	Pyruvate, phosphate dikinase regulatory protein 2	17996018	The pyruvate, orthophosphate dikinase regulatory proteins of Arabidopsis possess a novel, unprecedented Ser/Thr protein kinase primary structure.

Q9Y7U4	NSE3_SCHPO	Non-structural maintenance of chromosome element 3	15331764	Nse1, Nse2, and a novel subunit of the Smc5-Smc6 complex, Nse3, play a crucial role in meiosis.

Q76HP2	T132D_RAT	Transmembrane protein 132D	12966072	Molecular cloning of a novel transmembrane protein MOLT expressed by mature oligodendrocytes.

P38891	BCA1_YEAST	Branched-chain-amino-acid aminotransferase, mitochondrial	8702755	Two yeast homologs of ECA39, a target for c-Myc regulation, code for cytosolic and mitochondrial branched-chain amino acid aminotransferases.

O15264	MK13_HUMAN	Mitogen-activated protein kinase 13	9218798	Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases.

P05164	PERM_HUMAN	Myeloperoxidase	2903767	Multiple species of myeloperoxidase messenger RNAs produced by alternative splicing and differential polyadenylation.

Q9W1N6	GR59E_DROME	Putative gustatory receptor 59e	10710312	Candidate taste receptors in Drosophila.

Q9UK96	FBX10_HUMAN	F-box only protein 10	10531037	A family of mammalian F-box proteins.

O42173	PV1_XENLA	Homeobox protein pv.1	12890483	Active repression of organizer genes by C-terminal domain of PV.1.

O14777	NDC80_HUMAN	Kinetochore protein NDC80 homolog	9315664	HEC, a novel nuclear protein rich in leucine heptad repeats specifically involved in mitosis.

P53999	TCP4_HUMAN	Activated RNA polymerase II transcriptional coactivator p15	11389848	Evolutionarily conserved interaction between CstF-64 and PC4 links transcription, polyadenylation, and termination.

P85214	PROP1_GALME	Proline-rich antimicrobial peptide 1	17194500	Purification and characterization of eight peptides from Galleria mellonella immune hemolymph.

Q9CZV8	FXL20_MOUSE	F-box/LRR-repeat protein 20	17803915	SCRAPPER-dependent ubiquitination of active zone protein RIM1 regulates synaptic vesicle release.

Q61955	KLK8_MOUSE	Kallikrein-8	10196465	Injury induces neuropsin mRNA in the central nervous system.

Q9JJ40	NHRF3_RAT	Na(+)/H(+) exchange regulatory cofactor NHE-RF3	10829064	Identification of a PDZ-domain-containing protein that interacts with the scavenger receptor class B type I.

P13609	SRGN_MOUSE	Serglycin	7535771	A novel ligand for CD44 is serglycin, a hematopoietic cell lineage- specific proteoglycan. Possible involvement in lymphoid cell adherence and activation.

Q00342	FLT3_MOUSE	FL cytokine receptor	8384358	Biochemical characterization and analysis of the transforming potential of the FLT3/FLK2 receptor tyrosine kinase.

Q9VTE2	SUUR_DROME	Protein suppressor of underreplication	11901119	The Drosophila suppressor of underreplication protein binds to late- replicating regions of polytene chromosomes.

P06876	MYB_MOUSE	Transcriptional activator Myb	15082531	Wnt-1 signal induces phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK.

Q9M0Z3	KEA3_ARATH	K(+) efflux antiporter 3, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

P05059	CMGA_BOVIN	Chromogranin-A	9294131	Novel autocrine feedback control of catecholamine release. A discrete chromogranin a fragment is a noncompetitive nicotinic cholinergic antagonist.

P53914	KRE33_YEAST	UPF0202 protein KRE33	12150911	90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors.

P39086	GRIK1_HUMAN	Glutamate receptor, ionotropic kainate 1	8260617	Expression and novel subunit isoforms of glutamate receptor genes GluR5 and GluR6.

O88508	DNM3A_MOUSE	DNA (cytosine-5)-methyltransferase 3A	15456878	The PWWP domain of Dnmt3a and Dnmt3b is required for directing DNA methylation to the major satellite repeats at pericentric heterochromatin.

Q9M9M4	CSLD3_ARATH	Cellulose synthase-like protein D3	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

P30419	NMT1_HUMAN	Glycylpeptide N-tetradecanoyltransferase 1	9506952	A second mammalian N-myristoyltransferase.

O76003	GLRX3_HUMAN	Glutaredoxin-3	10636891	Inhibition of the c-Jun N-terminal kinase/AP-1 and NF-kappaB pathways by PICOT, a novel protein kinase C-interacting protein with a thioredoxin homology domain.

Q06945	SOX4_HUMAN	Transcription factor SOX-4	8268656	Characterization and mapping of the human SOX4 gene.

P0AFK6	POTC_ECOLI	Spermidine/putrescine transport system permease protein potC	1939142	Characteristics of the gene for a spermidine and putrescine transport system that maps at 15 min on the Escherichia coli chromosome.

P08069	IGF1R_HUMAN	Insulin-like growth factor 1 receptor	7679099	Role of tyrosine kinase activity in signal transduction by the insulin-like growth factor-I (IGF-I) receptor. Characterization of kinase-deficient IGF-I receptors and the action of an IGF-I-mimetic antibody (alpha IR-3).

P32345	PP4C_YEAST	Serine/threonine-protein phosphatase 4 catalytic subunit	10940301	Tripartite regulation of Gln3p by TOR, Ure2p, and phosphatases.

O95243	MBD4_HUMAN	Methyl-CpG-binding domain protein 4	12702765	Fas-associated death domain protein interacts with methyl-CpG binding domain protein 4: a potential link between genome surveillance and apoptosis.

Q70G58	NTRC_ORYSJ	Thioredoxin reductase NTRC	19345687	A proposed reaction mechanism for rice NADPH thioredoxin reductase C, an enzyme with protein disulfide reductase activity.

Q9C9Y6	TRXH9_ARATH	Thioredoxin H9	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

P29275	AA2BR_HUMAN	Adenosine receptor A2b	7558011	Cloning and chromosomal localization of the human A2b adenosine receptor gene (ADORA2B) and its pseudogene.

P25054	APC_HUMAN	Adenomatous polyposis coli protein	18281465	Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains.

P04632	CPNS1_HUMAN	Calpain small subunit 1	10639123	The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium.

Q92572	AP3S1_HUMAN	AP-3 complex subunit sigma-1	8697810	Cloning, expression pattern and mapping to 12p 13.2 --> p13.1 of CLAPS3, a gene encoding a novel clathrin-adaptor small chain.

Q55777	DNCH_SYNY3	1,4-dihydroxy-2-naphthoyl-CoA hydrolase	19321747	A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.

Q6R5J2	DISP1_DANRE	Protein dispatched homolog 1	15110707	Inactivation of dispatched 1 by the chameleon mutation disrupts hedgehog signalling in the zebrafish embryo.

Q9UBZ9	REV1_HUMAN	DNA repair protein REV1	11485998	Interactions in the error-prone postreplication repair proteins hREV1, hREV3, and hREV7.

Q9NA26	VPS28_CAEEL	Vacuolar protein sorting-associated protein 28 homolog	17895996	MVB-12, a fourth subunit of metazoan ESCRT-I, functions in receptor downregulation.

Q92685	ALG3_HUMAN	Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase	10581255	Carbohydrate deficient glycoprotein syndrome type IV: deficiency of dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase.

O13970	RT04_SCHPO	40S ribosomal protein mrp4, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q18825	BAR1_CAEEL	Beta-catenin/armadillo-related protein 1	11560894	The divergent Caenorhabditis elegans beta-catenin proteins BAR-1, WRM-1 and HMP-2 make distinct protein interactions but retain functional redundancy in vivo.

Q08818	MSC6_YEAST	Meiotic sister-chromatid recombination protein 6, mitochondrial	10511544	Genetic control of recombination partner preference in yeast meiosis. Isolation and characterization of mutants elevated for meiotic unequal sister-chromatid recombination.

P49903	SPS1_HUMAN	Selenide, water dikinase 1	7665581	Cloning and functional characterization of human selenophosphate synthetase, an essential component of selenoprotein synthesis.

Q9SNB9	TRP2_ARATH	Telomere repeat-binding protein 2	19962994	PAH-domain-specific interactions of the Arabidopsis transcription coregulator SIN3-LIKE1 (SNL1) with telomere-binding protein 1 and ALWAYS EARLY2 Myb-DNA binding factors.

Q9H488	OFUT1_HUMAN	GDP-fucose protein O-fucosyltransferase 1	9023546	Identification of a GDP-L-fucose:polypeptide fucosyltransferase and enzymatic addition of O-linked fucose to EGF domains.

O77059	CRY1_DROME	Cryptochrome-1	17298948	A novel photoreaction mechanism for the circadian blue light photoreceptor Drosophila cryptochrome.

Q03390	VPS60_YEAST	Vacuolar protein-sorting-associated protein 60	18032584	Novel Ist1-Did2 complex functions at a late step in multivesicular body sorting.

Q8BQ86	CHST8_MOUSE	Carbohydrate sulfotransferase 8	12944377	Mouse N-acetylgalactosamine 4-sulfotransferases-1 and -2. Molecular cloning, expression, chromosomal mapping and detection of their activity with GalNAcbeta1-4GlcNAcbeta1-octyl.

P36626	REC8_SCHPO	Meiotic recombination protein rec8	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

O14122	CUL4_SCHPO	Cullin-4	12695334	Cop9/signalosome subunits and Pcu4 regulate ribonucleotide reductase by both checkpoint-dependent and -independent mechanisms.

P32571	UBP4_YEAST	Ubiquitin carboxyl-terminal hydrolase 4	9119204	Catabolite inactivation of the yeast maltose transporter requires ubiquitin-ligase npi1/rsp5 and ubiquitin-hydrolase npi2/doa4.

Q9W7R6	SOX14_CHICK	Transcription factor SOX-14	10473124	Two distinct subgroups of Group B Sox genes for transcriptional activators and repressors: their expression during embryonic organogenesis of the chicken.

P54274	TERF1_HUMAN	Telomeric repeat-binding factor 1	12768206	POT1 as a terminal transducer of TRF1 telomere length control.

Q8BR65	SDS3_MOUSE	Sin3 histone deacetylase corepressor complex component SDS3	11909966	Identification of mammalian Sds3 as an integral component of the Sin3/histone deacetylase corepressor complex.

P45437	COPB_DROME	Coatomer subunit beta	8127899	Location of Golgi membranes with reference to dividing nuclei in syncytial Drosophila embryos.

P06858	LIPL_HUMAN	Lipoprotein lipase	17997385	Normal binding of lipoprotein lipase, chylomicrons, and apo-AV to GPIHBP1 containing a G56R amino acid substitution.

P0AG16	PUR1_ECOLI	Amidophosphoribosyltransferase	7037784	Glutamine phosphoribosylpyrophosphate amidotransferase from cloned Escherichia coli purF. NH2-terminal amino acid sequence, identification of the glutamine site, and trace metal analysis.

P53743	ESF2_YEAST	Pre-rRNA-processing protein ESF2	14562095	Global analysis of protein localization in budding yeast.

Q02205	MEH1_YEAST	Protein MEH1	16732272	A conserved GTPase-containing complex is required for intracellular sorting of the general amino-acid permease in yeast.

Q6UW88	EPGN_HUMAN	Epigen	15611079	Epigen, the last ligand of ErbB receptors, reveals intricate relationships between affinity and mitogenicity.

O75143	ATG13_HUMAN	Autophagy-related protein 13	19211835	Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy.

Q7TSE6	ST38L_MOUSE	Serine/threonine-protein kinase 38-like	15308672	Neuronal functions of the novel serine/threonine kinase Ndr2.

O43008	CRS1_SCHPO	Meiosis-specific cyclin crs1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P76114	MCBR_ECOLI	HTH-type transcriptional regulator mcbR	18309357	Escherichia coli transcription factor YncC (McbR) regulates colanic acid and biofilm formation by repressing expression of periplasmic protein YbiM (McbA).

P46668	ATHB6_ARATH	Homeobox-leucine zipper protein ATHB-6	12065416	Homeodomain protein ATHB6 is a target of the protein phosphatase ABI1 and regulates hormone responses in Arabidopsis.

O95206	PCDH8_HUMAN	Protocadherin-8	9787079	Characterization of two novel protocadherins (PCDH8 and PCDH9) localized on human chromosome 13 and mouse chromosome 14.

P36594	RPB1_SCHPO	DNA-directed RNA polymerase II subunit rpb1	2011520	Cloning and sequence determination of the Schizosaccharomyces pombe rpb1 gene encoding the largest subunit of RNA polymerase II.

P78508	IRK10_HUMAN	ATP-sensitive inward rectifier potassium channel 10	8995301	Cloning and characterization of two K+ inward rectifier (Kir) 1.1 potassium channel homologs from human kidney (Kir1.2 and Kir1.3).

P00763	TRY2_RAT	Anionic trypsin-2	6896710	Two similar but nonallelic rat pancreatic trypsinogens. Nucleotide sequences of the cloned cDNAs.

P13681	PP11_SCHPO	Serine/threonine-protein phosphatase PP1-1	7957097	Phosphorylation of dis2 protein phosphatase at the C-terminal cdc2 consensus and its potential role in cell cycle regulation.

P48723	HSP13_HUMAN	Heat shock 70 kDa protein 13	8131751	Stch encodes the 'ATPase core' of a microsomal stress 70 protein.

Q9Y5K2	KLK4_HUMAN	Kallikrein-4	10077646	Molecular cloning and characterization of prostase, an androgen- regulated serine protease with prostate-restricted expression.

P40693	RLP7_YEAST	Ribosome biogenesis protein RLP7	11087857	A nucleolar protein related to ribosomal protein L7 is required for an early step in large ribosomal subunit biogenesis.

Q04013	YHM2_YEAST	Mitochondrial DNA replication protein YHM2	9742088	A novel DNA-binding protein bound to the mitochondrial inner membrane restores the null mutation of mitochondrial histone Abf2p in Saccharomyces cerevisiae.

Q9VDW3	DMDB_DROME	Dystrophin, isoform B	17543506	Drosophila Dystrophin is required for integrity of the musculature.

Q9UJY1	HSPB8_HUMAN	Heat shock protein beta-8	10833516	A novel human gene similar to the protein kinase (PK) coding domain of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) codes for a serine-threonine PK and is expressed in melanoma cells.

O59760	YJM7_SCHPO	Putative uncharacterized hydrolase C1020.07	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8CIN4	PAK2_MOUSE	Serine/threonine-protein kinase PAK 2	18716323	Scrib regulates PAK activity during the cell migration process.

Q8NF91	SYNE1_HUMAN	Nesprin-1	11801724	Myne-1, a spectrin repeat transmembrane protein of the myocyte inner nuclear membrane, interacts with lamin A/C.

P41217	OX2G_HUMAN	OX-2 membrane glycoprotein	3032785	Characterization of the human homolog of the rat MRC OX-2 membrane glycoprotein.

Q03060	CREM_HUMAN	cAMP-responsive element modulator	10373550	Human Cdc34 and Rad6B ubiquitin-conjugating enzymes target repressors of cyclic AMP-induced transcription for proteolysis.

O70628	PDE9A_MOUSE	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	9624145	Identification and characterization of a novel family of cyclic nucleotide phosphodiesterases.

Q9VH48	CARM1_DROME	Probable histone-arginine methyltransferase CARMER	17459088	Tissue-dependent subcellular localization of Drosophila arginine methyl-transferase 4 (DART4), a coactivator whose overexpression affects neither viability nor differentiation.

P06103	EIF3B_YEAST	Eukaryotic translation initiation factor 3 subunit B	3029094	Molecular characterization of the yeast PRT1 gene in which mutations affect translation initiation and regulation of cell proliferation.

P03901	NU4LM_HUMAN	NADH-ubiquinone oxidoreductase chain 4L	3921850	Six unidentified reading frames of human mitochondrial DNA encode components of the respiratory-chain NADH dehydrogenase.

O80623	Y2393_ARATH	Probable receptor-like protein kinase At2g39360	17644812	A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome.

P34760	TSA1_YEAST	Peroxiredoxin TSA1	8344960	Cloning, sequencing, and mutation of thiol-specific antioxidant gene of Saccharomyces cerevisiae.

P83137	AFP3_MALPA	Antifungal protein 3	11302747	Purification and characterization of three antifungal proteins from cheeseweed (Malva parviflora).

Q84JM4	TPR3_ARATH	Topless-related protein 3	20360743	NINJA connects the co-repressor TOPLESS to jasmonate signalling.

Q27GK7	TPR4_ARATH	Topless-related protein 4	16763149	TOPLESS regulates apical embryonic fate in Arabidopsis.

Q9Z247	FKBP9_MOUSE	Peptidyl-prolyl cis-trans isomerase FKBP9	10524204	Biochemical analysis of mouse FKBP60, a novel member of the FKBP family.

Q8QGV6	NLK2_XENLA	Serine/threonine-protein kinase NLK2	16714285	NARF, an nemo-like kinase (NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF).

Q9JM73	SRF_MOUSE	Serum response factor	19350017	SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta1-integrin.

O84875	CDUB2_CHLTR	Deubiquitinase and deneddylase Dub2	16824101	Chlamydia trachomatis-derived deubiquitinating enzymes in mammalian cells during infection.

Q12383	TRM13_YEAST	tRNA guanosine-2'-O-methyltransferase TRM13	17242307	The 2'-O-methyltransferase responsible for modification of yeast tRNA at position 4.

P35222	CTNB1_HUMAN	Catenin beta-1	9065402	Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC.

P63165	SUMO1_HUMAN	Small ubiquitin-related modifier 1	15296745	A basis for SUMO protease specificity provided by analysis of human Senp2 and a Senp2-SUMO complex.

P08567	PLEK_HUMAN	Pleckstrin	2768345	Molecular analysis of pleckstrin: the major protein kinase C substrate of platelets.

P27615	SCRB2_RAT	Lysosome membrane protein 2	1715871	Cloning, sequencing, and expression of a cDNA encoding rat LIMP II, a novel 74-kDa lysosomal membrane protein related to the surface adhesion protein CD36.

Q7KNS3	LIS1_DROME	Lissencephaly-1 homolog	11056531	Drosophila Lis1 is required for neuroblast proliferation, dendritic elaboration and axonal transport.

Q9U9Y8	NLK_CAEEL	Serine/threonine kinase NLK	15066285	Phosphorylation by the beta-catenin/MAPK complex promotes 14-3-3- mediated nuclear export of TCF/POP-1 in signal-responsive cells in C. elegans.

Q9Y3D6	FIS1_HUMAN	Mitochondrial fission 1 protein	12861026	The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1.

Q9GUM2	BRE4_CAEEL	Beta-1,4-N-acetylgalactosaminyltransferase bre-4	12167666	Molecular cloning and enzymatic characterization of a UDP- GalNAc:GlcNAc(beta)-R beta1,4-N-acetylgalactosaminyltransferase from Caenorhabditis elegans.

Q96PH6	DB118_HUMAN	Beta-defensin 118	11564719	Primate epididymis-specific proteins: characterization of ESC42, a novel protein containing a trefoil-like motif in monkey and human.

Q10187	UCP6_SCHPO	UBA domain-containing protein 6	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q24338	ESC_DROME	Polycomb protein esc	7556071	The Polycomb-group gene, extra sex combs, encodes a nuclear member of the WD-40 repeat family.

Q9JL99	CLC1B_MOUSE	C-type lectin domain family 1 member B	10671229	Molecular characterization of two novel C-type lectin-like receptors, one of which is selectively expressed in human dendritic cells.

P49775	HNT2_YEAST	Bis(5'-adenosyl)-triphosphatase	1653209	Isolation and characterization of a dinucleoside triphosphatase from Saccharomyces cerevisiae.

Q90VV1	HES4B_XENLA	Transcription factor HES-4-B	15531363	Sequences downstream of the bHLH domain of the Xenopus hairy-related transcription factor-1 act as an extended dimerization domain that contributes to the selection of the partners.

P10163	PRB4_HUMAN	Basic salivary proline-rich protein 4	8373986	Alignment of amino acid and DNA sequences of human proline-rich proteins.

P33226	TORC_ECOLI	Cytochrome c-type protein torC	11056172	Electron transfer and binding of the c-type cytochrome TorC to the trimethylamine N-oxide reductase in Escherichia coli.

P36551	HEM6_HUMAN	Coproporphyrinogen-III oxidase, mitochondrial	8159699	Molecular cloning, sequencing, and functional expression of a cDNA encoding human coproporphyrinogen oxidase.

Q9R100	CAD17_MOUSE	Cadherin-17	10906147	The identification of a nonclassical cadherin expressed during B cell development and its interaction with surrogate light chain.

P36602	RIR1_SCHPO	Ribonucleoside-diphosphate reductase large chain	8479429	The cell cycle genes cdc22+ and suc22+ of the fission yeast Schizosaccharomyces pombe encode the large and small subunits of ribonucleotide reductase.

P57752	ACBP6_ARATH	Acyl-CoA-binding domain-containing protein 6	19121948	An Arabidopsis family of six acyl-CoA-binding proteins has three cytosolic members.

Q768S4	RPH3L_MOUSE	Rab effector Noc2	12578829	Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2.

Q80Z29	NAMPT_RAT	Nicotinamide phosphoribosyltransferase	12782293	Growth phase-dependent changes in the subcellular localization of pre-B-cell colony-enhancing factor.

O96923	GNRA_DICDI	Gelsolin-related protein of 125 kDa	16735078	A phototaxis signalling complex in Dictyostelium discoideum.

O74919	RNC1_SCHPO	RNA-binding protein rnc1	12931193	Feedback regulation of MAPK signalling by an RNA-binding protein.

Q94517	HDAC1_DROME	Histone deacetylase Rpd3	12697833	A 1-megadalton ESC/E(Z) complex from Drosophila that contains polycomblike and RPD3.

Q9S7B2	RS2_MAIZE	Protein rough sheath 2	16243907	Maize rough sheath2 and its Arabidopsis orthologue ASYMMETRIC LEAVES1 interact with HIRA, a predicted histone chaperone, to maintain knox gene silencing and determinacy during organogenesis.

P50528	PLO1_SCHPO	Serine/threonine-protein kinase plo1	15062098	Sid4p-Cdc11p assembles the septation initiation network and its regulators at the S. pombe SPB.

P03879	MBI4_YEAST	Intron-encoded RNA maturase bI4	11142386	The bI4 group I intron binds directly to both its protein splicing partners, a tRNA synthetase and maturase, to facilitate RNA splicing activity.

Q9QY02	YTDC1_RAT	YTH domain-containing protein 1	10564280	The interaction and colocalization of Sam68 with the splicing- associated factor YT521-B in nuclear dots is regulated by the Src family kinase p59fyn.

Q9UNE0	EDAR_HUMAN	Tumor necrosis factor receptor superfamily member EDAR	11039935	Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors.

Q15785	TOM34_HUMAN	Mitochondrial import receptor subunit TOM34	9324309	hTom34: a novel translocase for the import of proteins into human mitochondria.

P43425	GBG7_RAT	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7	7807587	G-protein gamma 7 subunit is selectively expressed in medium-sized neurons and dendrites of the rat neostriatum.

Q39192	SRK2D_ARATH	Serine/threonine-protein kinase SRK2D	15292193	Identification of nine sucrose nonfermenting 1-related protein kinases 2 activated by hyperosmotic and saline stresses in Arabidopsis thaliana.

Q10146	RRP6_SCHPO	Exosome complex exonuclease rrp6	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P11532	DMD_HUMAN	Dystrophin	16000376	Specific interaction of the actin-binding domain of dystrophin with intermediate filaments containing keratin 19.

Q12030	TAF10_YEAST	Transcription initiation factor TFIID subunit 10	10788514	Identification of two novel TAF subunits of the yeast Saccharomyces cerevisiae TFIID complex.

P0C0W9	RL11A_YEAST	60S ribosomal protein L11-A	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

P27303	EMRA_ECOLI	Multidrug resistance protein A	1409590	Emr, an Escherichia coli locus for multidrug resistance.

Q6NV32	PTMAA_DANRE	Prothymosin alpha-A	18351673	Differential expression of duplicated genes for prothymosin alpha during zebrafish development.

Q03096	EST3_YEAST	Telomere replication protein EST3	10898986	The Est3 protein is a subunit of yeast telomerase.

P46664	PURA2_MOUSE	Adenylosuccinate synthetase isozyme 2	8308018	Amplification of an adenylosuccinate synthetase gene in alanosine- resistant murine T-lymphoma cells. Molecular cloning of a cDNA encoding the 'non-muscle' isozyme.

Q9FNV8	MY114_ARATH	Transcription factor MYB114	16463103	The MYB transcription factor superfamily of Arabidopsis: expression analysis and phylogenetic comparison with the rice MYB family.

P59998	ARPC4_HUMAN	Actin-related protein 2/3 complex subunit 4	9230079	The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly.

Q14209	E2F2_HUMAN	Transcription factor E2F2	8246995	Cloning and characterization of E2F-2, a novel protein with the biochemical properties of transcription factor E2F.

Q9XGM8	MGAT1_ARATH	Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	15537386	Molecular basis of N-acetylglucosaminyltransferase I deficiency in Arabidopsis thaliana plants lacking complex N-glycans.

O88436	PAX4_RAT	Paired box protein Pax-4	10601637	Inhibitory effect of Pax4 on the human insulin and islet amyloid polypeptide (IAPP) promoters.

Q9H361	PABP3_HUMAN	Polyadenylate-binding protein 3	11328870	Human testis expresses a specific poly(A)-binding protein.

O35092	TI17A_RAT	Mitochondrial import inner membrane translocase subunit Tim17-A	9538267	Identification of the protein import components of the rat mitochondrial inner membrane, rTIM17, rTIM23, and rTIM44.

P50617	DEND_RAT	Dendrin	8915891	Characterization and sleep deprivation-induced expression modulation of dendrin, a novel dendritic protein in rat brain neurons.

O43001	SYJ1_SCHPO	Inositol-1,4,5-trisphosphate 5-phosphatase 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P11633	NHP6B_YEAST	Non-histone chromosomal protein 6B	11287614	High-mobility-group proteins NHP6A and NHP6B participate in activation of the RNA polymerase III SNR6 gene.

P15924	DESP_HUMAN	Desmoplakin	9887343	Haploinsufficiency of desmoplakin causes a striate subtype of palmoplantar keratoderma.

O42601	S17B1_XENLA	Transcription factor Sox-17-beta.1	11091074	Changes in embryonic cell fate produced by expression of an endodermal transcription factor, Xsox17.

Q9UNF0	PACN2_HUMAN	Protein kinase C and casein kinase substrate in neurons protein 2	10431838	PACSIN 2, a novel member of the PACSIN family of cytoplasmic adapter proteins.

Q02338	BDH_HUMAN	D-beta-hydroxybutyrate dehydrogenase, mitochondrial	1639787	Molecular cloning and characterization of (R)-3-hydroxybutyrate dehydrogenase from human heart.

Q99797	MIPEP_HUMAN	Mitochondrial intermediate peptidase	9073519	Cloning, expression, and chromosomal assignment of the human mitochondrial intermediate peptidase gene (MIPEP).

O14091	SUT1_SCHPO	General alpha-glucoside permease	11136464	Functional characterization of the alpha-glucoside transporter Sut1p from Schizosaccharomyces pombe, the first fungal homologue of plant sucrose transporters.

P18850	ATF6A_HUMAN	Cyclic AMP-dependent transcription factor ATF-6 alpha	10564271	Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress.

P15336	ATF2_HUMAN	Cyclic AMP-dependent transcription factor ATF-2	2529117	Leucine zipper structure of the protein CRE-BP1 binding to the cyclic AMP response element in brain.

Q9HCU4	CELR2_HUMAN	Cadherin EGF LAG seven-pass G-type receptor 2	10907856	The human homologue of flamingo, EGFL2, encodes a brain-expressed large cadherin-like protein with epidermal growth factor-like domains, and maps to chromosome 1p13.3-p21.1.

O00425	IF2B3_HUMAN	Insulin-like growth factor 2 mRNA-binding protein 3	9891060	A family of insulin-like growth factor II mRNA-binding proteins represses translation in late development.

Q76L33	PCYAB_ASTLO	Photoactivated adenylate cyclase subunit beta	16121285	Photoactivated adenylyl cyclase (PAC) genes in the flagellate Euglena gracilis mutant strains.

Q91905	FXI1B_XENLA	Forkhead box protein I1-B	15656969	Of fox and frogs: fox (fork head/winged helix) transcription factors in Xenopus development.

O88508	DNM3A_MOUSE	DNA (cytosine-5)-methyltransferase 3A	14752048	Modification of de novo DNA methyltransferase 3a (Dnmt3a) by SUMO-1 modulates its interaction with histone deacetylases (HDACs) and its capacity to repress transcription.

P07257	QCR2_YEAST	Cytochrome b-c1 complex subunit 2, mitochondrial	3028797	Subunit II of yeast QH2:cytochrome-c oxidoreductase. Nucleotide sequence of the gene and features of the protein.

Q61884	MNS1_MOUSE	Meiosis-specific nuclear structural protein 1	8032679	cDNA cloning and functional characterization of a meiosis-specific nuclear structural protein (MNS1).

Q53079	PSB1_RHOER	Proteasome subunit beta 1	14659753	Crystal structures of the Rhodococcus proteasome with and without its pro-peptides: implications for the role of the pro-peptide in proteasome assembly.

Q07478	SUB2_YEAST	ATP-dependent RNA helicase SUB2	11696331	The DECD box putative ATPase Sub2p is an early mRNA export factor.

O77059	CRY1_DROME	Cryptochrome-1	15258584	A constitutively active cryptochrome in Drosophila melanogaster.

Q922Y0	DYRK3_MOUSE	Dual specificity tyrosine-phosphorylation-regulated kinase 3	12356771	DYRK3 activation, engagement of protein kinase A/cAMP response element-binding protein, and modulation of progenitor cell survival.

Q12373	HIF1_YEAST	HAT1-interacting factor 1	14761951	Hif1 is a component of yeast histone acetyltransferase B, a complex mainly localized in the nucleus.

Q6IBS0	TWF2_HUMAN	Twinfilin-2	10406962	Cloning, expression and characterization of an A6 related protein.

P07913	TDH_ECOLI	L-threonine 3-dehydrogenase	2007567	L-threonine dehydrogenase from Escherichia coli. Identification of an active site cysteine residue and metal ion studies.

Q54SM3	PPIA_DICDI	Peptidyl-prolyl cis-trans isomerase A	8643519	Mutagenesis and gene identification in Dictyostelium by shotgun antisense.

Q9ULZ3	ASC_HUMAN	Apoptosis-associated speck-like protein containing a CARD	15030775	NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder.

P00520	ABL1_MOUSE	Tyrosine-protein kinase ABL1	11279004	Inhibition of cell migration by Abl family tyrosine kinases through uncoupling of Crk-CAS complexes.

P49687	NU145_YEAST	Nucleoporin NUP145	8044840	Nup145p is required for nuclear export of mRNA and binds homopolymeric RNA in vitro via a novel conserved motif.

P29830	HS176_ARATH	17.6 kDa class II heat shock protein	11576425	At-HSP17.6A, encoding a small heat-shock protein in Arabidopsis, can enhance osmotolerance upon overexpression.

Q06673	ECM30_YEAST	Protein ECM30	9335584	Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae.

Q60662	AKAP4_MOUSE	A-kinase anchor protein 4	8088444	The major fibrous sheath polypeptide of mouse sperm: structural and functional similarities to the A-kinase anchoring proteins.

P27105	STOM_HUMAN	Erythrocyte band 7 integral membrane protein	9642292	Oligomeric nature of the integral membrane protein stomatin.

Q12184	ADRX_YEAST	Adrenodoxin homolog, mitochondrial	10375636	YAH1 of Saccharomyces cerevisiae: a new essential gene that codes for a protein homologous to human adrenodoxin.

Q54JC0	CMBB_DICDI	Calmodulin-binding protein CmbB	16777069	Isolation, characterization, and bioinformatic analysis of calmodulin-binding protein cmbB reveals a novel tandem IP22 repeat common to many Dictyostelium and Mimivirus proteins.

P36553	HEM6_ECOLI	Coproporphyrinogen-III oxidase, aerobic	12975365	Oxygen-dependent coproporphyrinogen III oxidase (HemF) from Escherichia coli is stimulated by manganese.

P53032	SUT1_YEAST	Sterol uptake protein 1	11248676	SUT1 is a putative Zn[II]2Cys6-transcription factor whose upregulation enhances both sterol uptake and synthesis in aerobically growing Saccharomyces cerevisiae cells.

Q9JKB8	PRP18_RAT	Pre-mRNA-splicing factor 18	10924366	Expression cloning of KCRF, a potassium channel regulatory factor.

Q6P1K2	PMF1_HUMAN	Polyamine-modulated factor 1	11256947	Characterization of the interaction between the transcription factors human polyamine modulated factor (PMF-1) and NF-E2-related factor 2 (Nrf-2) in the transcriptional regulation of the spermidine/spermine N1-acetyltransferase (SSAT) gene.

Q96UQ7	RLA2_RHOGU	60S acidic ribosomal protein P2	12869567	Nonorganellar acyl carrier protein from oleaginous yeast is a homologue of ribosomal protein P2.

P38768	PIH1_YEAST	Protein interacting with Hsp90 1	14562095	Global analysis of protein localization in budding yeast.

Q06011	ECM19_YEAST	Protein ECM19	9335584	Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae.

Q55DM1	LVSA_DICDI	BEACH domain-containing protein lvsA	11872142	The Dictyostelium LvsA protein is localized on the contractile vacuole and is required for osmoregulation.

Q9UBD6	RHCG_HUMAN	Ammonium transporter Rh type C	11062476	The human Rhesus-associated RhAG protein and a kidney homologue promote ammonium transport in yeast.

Q9LKW9	NHX7_ARATH	Sodium/hydrogen exchanger 7	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

P35179	SC61G_YEAST	Protein transport protein SSS1	15831493	Subunits of the translocon interact with components of the oligosaccharyl transferase complex.

Q15562	TEAD2_HUMAN	Transcriptional enhancer factor TEF-4	19324877	TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition.

P81003	GVP35_DACSA	35 kDa gas vesicle protein C	1527496	The homologies of gas vesicle proteins.

Q03776	PRP42_YEAST	U1 small nuclear ribonucleoprotein component PRP42	9418882	Yeast pre-mRNA splicing requires a pair of U1 snRNP-associated tetratricopeptide repeat proteins.

Q92462	PUB1_SCHPO	E3 ubiquitin-protein ligase pub1	11956316	The novel HECT-type ubiquitin-protein ligase Pub2p shares partially overlapping function with Pub1p in Schizosaccharomyces pombe.

P32571	UBP4_YEAST	Ubiquitin carboxyl-terminal hydrolase 4	17376168	Evidence for a direct role of the Doa4 deubiquitinating enzyme in protein sorting into the MVB pathway.

Q12906	ILF3_HUMAN	Interleukin enhancer-binding factor 3	10400669	DRBP76, a double-stranded RNA-binding nuclear protein, is phosphorylated by the interferon-induced protein kinase, PKR.

Q9VM91	TTL3A_DROME	Tubulin glycylase 3A	19524510	Evolutionary divergence of enzymatic mechanisms for posttranslational polyglycylation.

P07207	NOTCH_DROME	Neurogenic locus Notch protein	11719214	Novel Notch alleles reveal a Deltex-dependent pathway repressing neural fate.

O75478	TAD2A_HUMAN	Transcriptional adapter 2-alpha	8552087	Identification of human proteins functionally conserved with the yeast putative adaptors ADA2 and GCN5.

Q8C2B3	HDAC7_MOUSE	Histone deacetylase 7	10640276	Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression.

Q54K32	RGAA_DICDI	Ras GTPase-activating-like protein rgaA	9056774	A Ras GAP is essential for cytokinesis and spatial patterning in Dictyostelium.

P11985	TC1D3_MOUSE	Tctex1 domain-containing protein 3	12849985	The protein of a new gene, Tctex4, interacts with protein kinase CK2beta subunit and is highly expressed in mouse testis.

Q6A333	ALY2_ARATH	Protein ALWAYS EARLY 2	19962994	PAH-domain-specific interactions of the Arabidopsis transcription coregulator SIN3-LIKE1 (SNL1) with telomere-binding protein 1 and ALWAYS EARLY2 Myb-DNA binding factors.

P34948	MPI_CANAL	Mannose-6-phosphate isomerase	7785330	Cloning and heterologous expression of the Candida albicans gene PMI 1 encoding phosphomannose isomerase.

Q7Z992	SST6_SCHPO	ESCRT-I complex subunit vps23	17660439	Essential roles of class E Vps proteins for sorting into multivesicular bodies in Schizosaccharomyces pombe.

P39112	DSS1_YEAST	Exoribonuclease II, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P29460	IL12B_HUMAN	Interleukin-12 subunit beta	11114383	Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12.

O15197	EPHB6_HUMAN	Ephrin type-B receptor 6	9207182	Expression of a kinase-defective Eph-like receptor in the normal human brain.

Q12018	CDC53_YEAST	Cell division control protein 53	9346238	F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex.

P0AGG2	TESB_ECOLI	Acyl-CoA thioesterase 2	1645722	Cloning, sequencing, and characterization of Escherichia coli thioesterase II.

Q9P801	RML9_SCHPO	Probable 60 ribosomal protein L9, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q09796	KA111_SCHPO	Importin beta-like protein kap111	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

Q04179	URH1_YEAST	Uridine nucleosidase	12111094	The URH1 uridine ribohydrolase of Saccharomyces cerevisiae.

P32300	OPRD_MOUSE	Delta-type opioid receptor	8393575	Cloning and functional comparison of kappa and delta opioid receptors from mouse brain.

Q6DCQ1	IRX2_XENLA	Iroquois-class homeodomain protein irx-2	9427752	Xiro, a Xenopus homolog of the Drosophila Iroquois complex genes, controls development at the neural plate.

P36877	2ABB_RAT	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform	18940801	The spinocerebellar ataxia 12 gene product and protein phosphatase 2A regulatory subunit Bbeta2 antagonizes neuronal survival by promoting mitochondrial fission.

P08708	RS17_HUMAN	40S ribosomal protein S17	3240863	The transcriptionally active human ribosomal protein S17 gene.

P09081	BCD_DROME	Homeotic protein bicoid	11455422	Drosophila SAP18, a member of the Sin3/Rpd3 histone deacetylase complex, interacts with Bicoid and inhibits its activity.

P97546	NPTN_RAT	Neuroplastin	16925595	The cell adhesion molecule neuroplastin-65 inhibits hippocampal long- term potentiation via a mitogen-activated protein kinase p38-dependent reduction in surface expression of GluR1-containing glutamate receptors.

P59110	SENP1_MOUSE	Sentrin-specific protease 1	15923632	Mutation of SENP1/SuPr-2 reveals an essential role for desumoylation in mouse development.

Q9BPZ3	PAIP2_HUMAN	Polyadenylate-binding protein-interacting protein 2	11172725	Translational repression by a novel partner of human poly(A) binding protein, Paip2.

P48547	KCNC1_HUMAN	Potassium voltage-gated channel subfamily C member 1	8449507	Localization of a highly conserved human potassium channel gene (NGK2-KV4; KCNC1) to chromosome 11p15.

Q6DN12	MCTP2_HUMAN	Multiple C2 and transmembrane domain-containing protein 2	15528213	Evolutionarily conserved multiple C2 domain proteins with two transmembrane regions (MCTPs) and unusual Ca2+ binding properties.

Q7SIC1	FUCL_ANGAN	Fucolectin	15207656	Lectinochemical studies on the affinity of Anguilla anguilla agglutinin for mammalian glycotopes.

Q39011	KSG7_ARATH	Shaggy-related protein kinase eta	11820813	The UCU1 Arabidopsis gene encodes a SHAGGY/GSK3-like kinase required for cell expansion along the proximodistal axis.

Q8BWN8	ACOT4_MOUSE	Acyl-coenzyme A thioesterase 4	10567408	Peroxisome proliferator-induced long chain acyl-CoA thioesterases comprise a highly conserved novel multi-gene family involved in lipid metabolism.

P02533	K1C14_HUMAN	Keratin, type I cytoskeletal 14	11724817	The nonhelical tail domain of keratin 14 promotes filament bundling and enhances the mechanical properties of keratin intermediate filaments in vitro.

Q9UBC1	IKBL1_HUMAN	NF-kappa-B inhibitor-like protein 1	8081366	Characterization of a novel gene in the human major histocompatibility complex that encodes a potential new member of the I kappa B family of proteins.

Q9HBI6	CP4FB_HUMAN	Cytochrome P450 4F11	10964514	A novel human cytochrome P450 4F isoform (CYP4F11): cDNA cloning, expression, and genomic structural characterization.

Q8WTX9	ZDHC1_HUMAN	Probable palmitoyltransferase ZDHHC1	10395086	The DHHC domain: a new highly conserved cysteine-rich motif.

Q00325	MPCP_HUMAN	Phosphate carrier protein, mitochondrial	8144629	The sequences of human and bovine genes of the phosphate carrier from mitochondria contain evidence of alternatively spliced forms.

Q8AV66	TBX6_XENLA	T-box transcription factor TBX6	11737146	Cloning and characterization of the T-box gene Tbx6 in Xenopus laevis.

Q9UBP6	TRMB_HUMAN	tRNA (guanine-N(7)-)-methyltransferase	15861136	The tRNA methylase METTL1 is phosphorylated and inactivated by PKB and RSK in vitro and in cells.

Q9DBR0	AKAP8_MOUSE	A-kinase anchor protein 8	16751186	Interaction between fidgetin and protein kinase A-anchoring protein AKAP95 is critical for palatogenesis in the mouse.

Q6W5C0	CXCL3_MOUSE	C-X-C motif chemokine 3	14764687	IL-10-conditioned dendritic cells, decommissioned for recruitment of adaptive immunity, elicit innate inflammatory gene products in response to danger signals.

P37044	GON2_HAPBU	Progonadoliberin-2	8108425	A second gene for gonadotropin-releasing hormone: cDNA and expression pattern in the brain.

Q9H160	ING2_HUMAN	Inhibitor of growth protein 2	16387653	ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.

P54687	BCAT1_HUMAN	Branched-chain-amino-acid aminotransferase, cytosolic	16141215	Structural determinants for branched-chain aminotransferase isozyme- specific inhibition by the anticonvulsant drug gabapentin.

P22575	TIP_SHV2C	Tyrosine-protein kinase-interacting protein	9175835	Tap: a novel cellular protein that interacts with tip of herpesvirus saimiri and induces lymphocyte aggregation.

Q9TXJ0	CMK1_CAEEL	Calcium/calmodulin-dependent protein kinase type 1	14711416	The CMK-1 CaMKI and the TAX-4 Cyclic nucleotide-gated channel regulate thermosensory neuron gene expression and function in C. elegans.

Q8WXG6	MADD_HUMAN	MAP kinase-activating death domain protein	11577081	Contrasting effects of IG20 and its splice isoforms, MADD and DENN- SV, on tumor necrosis factor alpha-induced apoptosis and activation of caspase-8 and -3.

P42753	CCD31_ARATH	Cyclin-D3-1	16517759	The D-type cyclin CYCD3;1 is limiting for the G1-to-S-phase transition in Arabidopsis.

P13010	XRCC5_HUMAN	X-ray repair cross-complementing protein 5	12145306	Regulation of osteocalcin gene expression by a novel Ku antigen transcription factor complex.

Q03833	GIS1_YEAST	Transcriptional activator/repressor GIS1	12799368	Regulation of the yeast DPP1-encoded diacylglycerol pyrophosphate phosphatase by transcription factor Gis1p.

Q6NKW9	E138_ARATH	Glucan endo-1,3-beta-glucosidase 8	14517339	Proteomic analysis of glycosylphosphatidylinositol-anchored membrane proteins.

Q9HFF5	PDS5_SCHPO	Sister chromatid cohesion protein pds5	11861765	Fission yeast Pds5 is required for accurate chromosome segregation and for survival after DNA damage or metaphase arrest.

Q8K1B8	URP2_MOUSE	Fermitin family homolog 3	16876785	The Kindlins: subcellular localization and expression during murine development.

P23693	TNNI3_RAT	Troponin I, cardiac muscle	9065755	Regulation of the rat cardiac troponin I gene by the transcription factor GATA-4.

P16235	LSHR_RAT	Lutropin-choriogonadotropic hormone receptor	2925659	Purification, characterization, and amino-terminal sequence of rat ovarian receptor for luteinizing hormone/human choriogonadotropin.

P40463	VHS2_YEAST	Protein VHS2	12518319	Identification of multicopy suppressors of cell cycle arrest at the G1-S transition in Saccharomyces cerevisiae.

P41890	SCN1_SCHPO	Cut9-interacting protein scn1	7798319	Bypassing anaphase by fission yeast cut9 mutation: requirement of cut9+ to initiate anaphase.

P08311	CATG_HUMAN	Cathepsin G	2569462	Genomic organization and chromosomal localization of the human cathepsin G gene.

P29066	ARRB1_RAT	Beta-arrestin-1	12519791	Role of G protein-coupled receptor kinase 4 and beta-arrestin 1 in agonist-stimulated metabotropic glutamate receptor 1 internalization and activation of mitogen-activated protein kinases.

Q91VE0	S27A4_MOUSE	Long-chain fatty acid transport protein 4	14512415	Targeted deletion of fatty acid transport protein-4 results in early embryonic lethality.

Q21642	HRG1_CAEEL	Heme transporter hrg-1	18418376	Haem homeostasis is regulated by the conserved and concerted functions of HRG-1 proteins.

Q08887	NDD1_YEAST	Nuclear division defective protein 1	10207056	NDD1, a high-dosage suppressor of cdc28-1N, is essential for expression of a subset of late-S-phase-specific genes in Saccharomyces cerevisiae.

P26263	PDC6_YEAST	Pyruvate decarboxylase isozyme 3	12499363	The catabolism of amino acids to long chain and complex alcohols in Saccharomyces cerevisiae.

Q8IN94	OSA_DROME	Trithorax group protein osa	10601025	Osa associates with the Brahma chromatin remodeling complex and promotes the activation of some target genes.

P00957	SYA_ECOLI	Alanyl-tRNA synthetase	7005211	Purification and properties of alanine tRNA synthetase from Escherichia coli A tetramer of identical subunits.

Q9FZ48	UBC36_ARATH	Ubiquitin-conjugating enzyme E2 36	16339806	Genome analysis and functional characterization of the E2 and RING- type E3 ligase ubiquitination enzymes of Arabidopsis.

O93248	OPA1_ONCMA	Dynamin-like 120 kDa protein, mitochondrial	9708909	Isolation of a cDNA for a novel 120-kDa GTP-binding protein expressed in motor neurons in the salmon brain.

P79065	TIP1_SCHPO	Tip elongation protein 1	11007487	CLIP170-like tip1p spatially organizes microtubular dynamics in fission yeast.

Q13158	FADD_HUMAN	Protein FADD	7536190	A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain.

Q08818	MSC6_YEAST	Meiotic sister-chromatid recombination protein 6, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

Q15287	RNPS1_HUMAN	RNA-binding protein with serine-rich domain 1	11477570	Binding of a SART3 tumor-rejection antigen to a pre-mRNA splicing factor RNPS1: a possible regulation of splicing by a complex formation.

P0A910	OMPA_ECOLI	Outer membrane protein A	1370823	Pore-forming activity of OmpA protein of Escherichia coli.

Q63207	FA10_RAT	Coagulation factor X	8578539	Evidence for competition between vitamin K-dependent clotting factors for intracellular processing by the vitamin K-dependent gamma- carboxylase.

Q9US44	YIZG_SCHPO	Uncharacterized transporter C1002.16c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O74804	EST1_SCHPO	Telomere elongation protein est1	12676088	Telomere maintenance in fission yeast requires an Est1 ortholog.

O95393	BMP10_HUMAN	Bone morphogenetic protein 10	16049014	Identification of receptors and signaling pathways for orphan bone morphogenetic protein/growth differentiation factor ligands based on genomic analyses.

Q42029	PSBP1_ARATH	Oxygen-evolving enhancer protein 2-1, chloroplastic	11826309	Central functions of the lumenal and peripheral thylakoid proteome of Arabidopsis determined by experimentation and genome-wide prediction.

P22557	HEM0_HUMAN	5-aminolevulinate synthase, erythroid-specific, mitochondrial	2050125	Human erythroid 5-aminolevulinate synthase: promoter analysis and identification of an iron-responsive element in the mRNA.

Q9H6K4	OPA3_HUMAN	Optic atrophy 3 protein	15342707	OPA3 gene mutations responsible for autosomal dominant optic atrophy and cataract.

Q9LY91	AGP6_ARATH	Classical arabinogalactan protein 6	10451111	Glycosylphosphatidylinositol-anchored cell-surface proteins from Arabidopsis.

Q9Y675	SNURF_HUMAN	SNRPN upstream reading frame protein	10318933	An imprinted, mammalian bicistronic transcript encodes two independent proteins.

Q9JKD6	CLD5_RAT	Claudin-5	12403818	Distinct claudins and associated PDZ proteins form different autotypic tight junctions in myelinating Schwann cells.

O42643	PRP22_SCHPO	Pre-mRNA-splicing factor ATP-dependent RNA helicase prp22	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P62259	1433E_MOUSE	14-3-3 protein epsilon	15722337	Phosphorylation of grb10 regulates its interaction with 14-3-3.

Q8IXK0	PHC2_HUMAN	Polyhomeotic-like protein 2	10976766	A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening.

Q9FII5	Y5148_ARATH	Probable leucine-rich repeat receptor-like protein kinase At5g61480	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P49736	MCM2_HUMAN	DNA replication licensing factor MCM2	11095689	The human homolog of Saccharomyces cerevisiae Mcm10 interacts with replication factors and dissociates from nuclease-resistant nuclear structures in G(2) phase.

P39769	PHP_DROME	Polyhomeotic-proximal chromatin protein	12771214	The Drosophila Corto protein interacts with Polycomb-group proteins and the GAGA factor.

P24864	CCNE1_HUMAN	G1/S-specific cyclin-E1	8207080	Alternative splicing of human cyclin E.

P53266	SHY1_YEAST	Cytochrome oxidase assembly protein SHY1	9162072	SHY1, the yeast homolog of the mammalian SURF-1 gene, encodes a mitochondrial protein required for respiration.

P05787	K2C8_HUMAN	Keratin, type II cytoskeletal 8	16608857	Keratin 20 serine 13 phosphorylation is a stress and intestinal goblet cell marker.

Q9YGL6	PALM_CHICK	Paralemmin	9813098	Paralemmin, a prenyl-palmitoyl-anchored phosphoprotein abundant in neurons and implicated in plasma membrane dynamics and cell process formation.

P37267	CBP4_YEAST	Assembly factor CBP4	8063753	Characterization of CBP4, a new gene essential for the expression of ubiquinol-cytochrome c reductase in Saccharomyces cerevisiae.

P51807	DYLT1_MOUSE	Dynein light chain Tctex-type 1	10559191	Receptor-independent activators of heterotrimeric G-protein signaling pathways.

Q9XFS9	DXR_ARATH	1-deoxy-D-xylulose 5-phosphate reductoisomerase, chloroplastic	12177470	Expression and molecular analysis of the Arabidopsis DXR gene encoding 1-deoxy-D-xylulose 5-phosphate reductoisomerase, the first committed enzyme of the 2-C-methyl-D-erythritol 4-phosphate pathway.

O08574	MESP2_MOUSE	Mesoderm posterior protein 2	10887078	MesP1 and MesP2 are essential for the development of cardiac mesoderm.

Q19203	UNC98_CAEEL	Zinc finger protein unc-98	16790495	Caenorhabditis elegans UNC-96 is a new component of M-lines that interacts with UNC-98 and paramyosin and is required in adult muscle for assembly and/or maintenance of thick filaments.

Q9HB89	NMUR1_HUMAN	Neuromedin-U receptor 1	9782091	Cloning and characterization of a human and murine T-cell orphan G- protein-coupled receptor similar to the growth hormone secretagogue and neurotensin receptors.

Q9GZX7	AICDA_HUMAN	Activation-induced cytidine deaminase	10950930	Isolation, tissue distribution, and chromosomal localization of the human activation-induced cytidine deaminase (hAID) gene.

O75663	TIPRL_HUMAN	TIP41-like protein	17384681	Identification of a PP2A-interacting protein that functions as a negative regulator of phosphatase activity in the ATM/ATR signaling pathway.

P53769	CWC24_YEAST	Pre-mRNA-splicing factor CWC24	11884590	Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

P53965	SIW14_YEAST	Tyrosine-protein phosphatase SIW14	14562095	Global analysis of protein localization in budding yeast.

Q55CC5	BECNA_DICDI	Beclin-1-like protein A	14736886	Dictyostelium macroautophagy mutants vary in the severity of their developmental defects.

Q16584	M3K11_HUMAN	Mitogen-activated protein kinase kinase kinase 11	11053428	The kinase activation loop is the key to mixed lineage kinase-3 activation via both autophosphorylation and hematopoietic progenitor kinase 1 phosphorylation.

P38219	OLA1_YEAST	Uncharacterized GTP-binding protein OLA1	16284124	An integrated mass spectrometry-based proteomic approach: quantitative analysis of tandem affinity-purified in vivo cross-linked protein complexes (QTAX) to decipher the 26 S proteasome-interacting network.

P38211	GPI18_YEAST	GPI mannosyltransferase 2	15720390	Saccharomyces cerevisiae Ybr004c and its human homologue are required for addition of the second mannose during glycosylphosphatidylinositol precursor assembly.

Q9I8V2	SMAD1_DANRE	Mothers against decapentaplegic homolog 1	10590480	Smad1 and smad5 have distinct roles during dorsoventral patterning of the zebrafish embryo.

Q16527	CSRP2_HUMAN	Cysteine and glycine-rich protein 2	8626582	Molecular cloning and characterization of SmLIM, a developmentally regulated LIM protein preferentially expressed in aortic smooth muscle cells.

Q38890	GUN25_ARATH	Endoglucanase 25	16284310	An Arabidopsis endo-1,4-beta-D-glucanase involved in cellulose synthesis undergoes regulated intracellular cycling.

Q9USK7	YJ2I_SCHPO	Uncharacterized protein C4B3.18	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P70470	LYPA1_RAT	Acyl-protein thioesterase 1	9644627	cDNA cloning and expression of a novel family of enzymes with calcium-independent phospholipase A2 and lysophospholipase activities.

P29466	CASP1_HUMAN	Caspase-1	1373520	Molecular cloning of the interleukin-1 beta converting enzyme.

P32768	FLO1_YEAST	Flocculation protein FLO1	7483845	The Saccharomyces cerevisiae FLO1 flocculation gene encodes for a cell surface protein.

Q99N89	RM43_MOUSE	39S ribosomal protein L43, mitochondrial	11279069	Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria.

Q5SXA9	KIBRA_MOUSE	Protein KIBRA	18190796	KIBRA interacts with discoidin domain receptor 1 to modulate collagen-induced signalling.

Q9HCE7	SMUF1_HUMAN	E3 ubiquitin-protein ligase SMURF1	19937093	Ubiquitin ligase Smurf1 targets TRAF family proteins for ubiquitination and degradation.

Q9FG36	TRL31_ARATH	Thioredoxin-like 3-1, chloroplastic	19259774	A novel extended family of stromal thioredoxins.

O02213	SER2_CAEEL	Tyramine receptor ser-2	12354282	Characterization of a tyramine receptor from Caenorhabditis elegans.

O96009	NAPSA_HUMAN	Napsin-A	9877162	Napsins: new human aspartic proteinases. Distinction between two closely related genes.

Q9WUL7	ARL3_MOUSE	ADP-ribosylation factor-like protein 3	10518933	The delta subunit of rod specific cyclic GMP phosphodiesterase, PDE delta, interacts with the Arf-like protein Arl3 in a GTP specific manner.

Q80W65	PCSK9_MOUSE	Proprotein convertase subtilisin/kexin type 9	12552133	The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation.

Q9VQ66	NPLP4_DROME	Neuropeptide-like 4	12171930	Peptidomics of the larval Drosophila melanogaster central nervous system.

Q24459	PCL_DROME	Polycomb protein Pcl	12697833	A 1-megadalton ESC/E(Z) complex from Drosophila that contains polycomblike and RPD3.

P83012	COX5A_SCYCA	Cytochrome c oxidase subunit 5A, mitochondrial	11676495	N-terminal sequences of small ion channels in rectal glands of sharks: a biochemical hallmark for classification and phylogeny?

O96382	DFP11_HYPCU	Putative defense protein Hdd11	9818384	Isolation and characterization of immune-related genes from the fall webworm, Hyphantria cunea, using PCR-based differential display and subtractive cloning.

P53567	CEBPG_HUMAN	CCAAT/enhancer-binding protein gamma	7665092	Cloning of the cDNA encoding human C/EBP gamma, a protein binding to the PRE-I enhancer element of the human interleukin-4 promoter.

Q07468	VAM6_YEAST	Vacuolar morphogenesis protein 6	16601699	Purification of active HOPS complex reveals its affinities for phosphoinositides and the SNARE Vam7p.

P80314	TCPB_MOUSE	T-complex protein 1 subunit beta	7953530	Identification of six Tcp-1-related genes encoding divergent subunits of the TCP-1-containing chaperonin.

P40078	NSA2_YEAST	Ribosome biogenesis protein NSA2	11583614	Composition and functional characterization of yeast 66S ribosome assembly intermediates.

Q9NQC8	IFT46_HUMAN	Intraflagellar transport protein 46 homolog	10873569	Characterization of five novel human genes in the 11q13-q22 region.

Q96PL5	ERMAP_HUMAN	Erythroid membrane-associated protein	11549310	Cloning and characterization of human erythroid membrane-associated protein, human ERMAP.

Q54B82	CSN4_DICDI	COP9 signalosome complex subunit 4	16781008	The COP9 signalosome regulates cell proliferation of Dictyostelium discoideum.

P53230	MMP37_YEAST	Mitochondrial import protein MMP37	14562095	Global analysis of protein localization in budding yeast.

Q9H4E5	RHOJ_HUMAN	Rho-related GTP-binding protein RhoJ	10967094	Characterization of TCL, a new GTPase of the Rho family related to TC10 and Cdc42.

Q9Y3Q8	T22D4_HUMAN	TSC22 domain family protein 4	10488076	Transforming growth factor-beta-stimulated clone-22 is a member of a family of leucine zipper proteins that can homo- and heterodimerize and has transcriptional repressor activity.

Q96301	SPY_ARATH	Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

O74968	RU1A_SCHPO	U1 small nuclear ribonucleoprotein usp102	17264129	Proteomic analysis of the U1 snRNP of Schizosaccharomyces pombe reveals three essential organism-specific proteins.

Q86HE5	CF451_DICDI	Counting factor 45-1	12912898	CF45-1, a secreted protein which participates in Dictyostelium group size regulation.

O94993	SOX30_HUMAN	Transcription factor SOX-30	10359848	Identification of a novel Sry-related gene and its germ cell-specific expression.

Q01831	XPC_HUMAN	DNA repair protein complementing XP-C cells	8168482	Purification and cloning of a nucleotide excision repair complex involving the Xeroderma pigmentosum group C protein and a human homologue of yeast RAD23.

Q03529	SCS7_YEAST	Ceramide very long chain fatty acid hydroxylase SCS7	9353282	Fah1p, a Saccharomyces cerevisiae cytochrome b5 fusion protein, and its Arabidopsis thaliana homolog that lacks the cytochrome b5 domain both function in the alpha-hydroxylation of sphingolipid-associated very long chain fatty acids.

P56523	CLR3_SCHPO	Histone deacetylase clr3	9755190	Histone deacetylase homologs regulate epigenetic inheritance of transcriptional silencing and chromosome segregation in fission yeast.

Q9EPL2	CSTN1_MOUSE	Calsyntenin-1	11161476	Calsyntenin-1, a proteolytically processed postsynaptic membrane protein with a cytoplasmic calcium-binding domain.

O94669	AP3M_SCHPO	AP-3 complex subunit mu	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P11171	41_HUMAN	Protein 4.1	11003675	Protein 4.1 R-135 interacts with a novel centrosomal protein (CPAP) which is associated with the gamma-tubulin complex.

P14742	GFA1_YEAST	Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	2656689	Cloning of the glutamine:fructose-6-phosphate amidotransferase gene from yeast. Pheromonal regulation of its transcription.

Q9P7F4	YKK1_SCHPO	Zinc-type alcohol dehydrogenase-like protein C2E1P3.01	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P47069	MPS3_YEAST	Spindle pole body assembly component MPS3	18585352	Rapid telomere movement in meiotic prophase is promoted by NDJ1, MPS3, and CSM4 and is modulated by recombination.

Q4V7H8	BORE2_XENLA	Borealin-2	17199039	Chromosomal enrichment and activation of the aurora B pathway are coupled to spatially regulate spindle assembly.

Q9LL84	DNLI4_ARATH	DNA ligase 4	12853643	The Arabidopsis AtLIG4 gene is required for the repair of DNA damage, but not for the integration of Agrobacterium T-DNA.

Q9NTG7	SIRT3_HUMAN	NAD-dependent deacetylase sirtuin-3, mitochondrial	19535340	Crystal structures of human SIRT3 displaying substrate-induced conformational changes.

Q93099	HGD_HUMAN	Homogentisate 1,2-dioxygenase	8782815	The molecular basis of alkaptonuria.

Q9US01	YIRD_SCHPO	Uncharacterized protein C664.13	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q54T86	DWWA_DICDI	WW domain-containing protein A	14595117	DWWA, a novel protein containing two WW domains and an IQ motif, is required for scission of the residual cytoplasmic bridge during cytokinesis in Dictyostelium.

P39900	MMP12_HUMAN	Macrophage metalloelastase	8226919	Cloning and characterization of a unique elastolytic metalloproteinase produced by human alveolar macrophages.

Q9BZA7	PC11X_HUMAN	Protocadherin-11 X-linked	10644456	Identification of a novel protocadherin gene (PCDH11) on the human XY homology region in Xq21.3.

Q8AW92	LMO4A_XENLA	LIM domain transcription factor LMO4-A	14651938	Xenopus Xlmo4 is a GATA cofactor during ventral mesoderm formation and regulates Ldb1 availability at the dorsal mesoderm and the neural plate.

O54864	SUV91_MOUSE	Histone-lysine N-methyltransferase SUV39H1	11788710	Functional and physical interaction between the histone methyl transferase Suv39H1 and histone deacetylases.

Q9M276	ATB12_ARATH	Homeobox-leucine zipper protein ATHB-12	15604708	The homeobox genes ATHB12 and ATHB7 encode potential regulators of growth in response to water deficit in Arabidopsis.

Q99P91	GPNMB_MOUSE	Transmembrane glycoprotein NMB	11114299	Molecular cloning of a dendritic cell-associated transmembrane protein, DC-HIL, that promotes RGD-dependent adhesion of endothelial cells through recognition of heparan sulfate proteoglycans.

Q90Y63	GON1_RANCA	Progonadoliberin-1	11170016	Cloning and characterization of cDNAs encoding the GnRH1 and GnRH2 precursors from bullfrog (Rana catesbeiana).

O14132	PIT1_SCHPO	Sporulation protein kinase pit1	10747048	Autoregulated expression of Schizosaccharomyces pombe meiosis- specific transcription factor Mei4 and a genome-wide search for its target genes.

Q9FFP9	SRK2H_ARATH	Serine/threonine-protein kinase SRK2H	15292193	Identification of nine sucrose nonfermenting 1-related protein kinases 2 activated by hyperosmotic and saline stresses in Arabidopsis thaliana.

Q401N2	ZACN_HUMAN	Zinc-activated ligand-gated ion channel	12381728	A novel class of ligand-gated ion channel is activated by Zn2+.

P25336	MSH3_YEAST	DNA mismatch repair protein MSH3	16781730	Mismatch repair factor MSH2-MSH3 binds and alters the conformation of branched DNA structures predicted to form during genetic recombination.

Q9JHR9	NRIP2_MOUSE	Nuclear receptor-interacting protein 2	10860982	Differential ligand-dependent protein-protein interactions between nuclear receptors and a neuronal-specific cofactor.

Q9QZX7	SRR_MOUSE	Serine racemase	10557334	Serine racemase: a glial enzyme synthesizing D-serine to regulate glutamate-N-methyl-D-aspartate neurotransmission.

Q8BHN0	PPM1L_MOUSE	Protein phosphatase 1L	12556533	Regulation of the interleukin-1-induced signaling pathways by a novel member of the protein phosphatase 2C family (PP2Cepsilon).

O75339	CILP1_HUMAN	Cartilage intermediate layer protein 1	9722583	A novel cartilage protein (CILP) present in the mid-zone of human articular cartilage increases with age.

P10275	ANDR_HUMAN	Androgen receptor	16027218	Huntingtin interacting protein 1 modulates the transcriptional activity of nuclear hormone receptors.

P38114	TBS1_YEAST	Uncharacterized transcriptional regulatory protein TBS1	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q8L940	PDX13_ARATH	Pyridoxal biosynthesis protein PDX1.3	16157873	Vitamin B6 biosynthesis in higher plants.

O94459	SCC4_SCHPO	Sister chromatid cohesion protein ssl3	16682348	A screen for cohesion mutants uncovers ssl3, the fission yeast counterpart of the cohesin loading factor scc4.

P53280	CF130_YEAST	Protein CAF130	11733989	Purification and characterization of the 1.0 MDa CCR4-NOT complex identifies two novel components of the complex.

O76039	CDKL5_HUMAN	Cyclin-dependent kinase-like 5	15917271	CDKL5 belongs to the same molecular pathway of MeCP2 and it is responsible for the early-onset seizure variant of Rett syndrome.

A0A1F4	EYS_DROME	Protein eyes shut	17036004	Transforming the architecture of compound eyes.

P61244	MAX_HUMAN	Protein max	15960975	Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

Q9VNV3	DDX1_DROME	ATP-dependent RNA helicase Ddx1	8666277	A Drosophila melanogaster homologue of the human DEAD-box gene DDX1.

O42907	YBAG_SCHPO	Uncharacterized protein C119.16c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9VXN9	PGPLE_DROME	Peptidoglycan-recognition protein LE	11106397	A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster.

Q9USM4	LUC7_SCHPO	U1 snRNP-associated protein usp106	17264129	Proteomic analysis of the U1 snRNP of Schizosaccharomyces pombe reveals three essential organism-specific proteins.

Q94BT6	ADO1_ARATH	Adagio protein 1	12795696	Protein interaction analysis of SCF ubiquitin E3 ligase subunits from Arabidopsis.

Q5GIT4	VGFR2_DANRE	Vascular endothelial growth factor receptor 2	16617120	Distinct genetic interactions between multiple Vegf receptors are required for development of different blood vessel types in zebrafish.

P20965	PABPA_XENLA	Polyadenylate-binding protein 1-A	10970864	Multiple portions of poly(A)-binding protein stimulate translation in vivo.

Q42371	ERECT_ARATH	LRR receptor-like serine/threonine-protein kinase ERECTA	11910003	KNAT1 and ERECTA regulate inflorescence architecture in Arabidopsis.

O60551	NMT2_HUMAN	Glycylpeptide N-tetradecanoyltransferase 2	9506952	A second mammalian N-myristoyltransferase.

P43565	RIM15_YEAST	Serine/threonine-protein kinase RIM15	9744870	Saccharomyces cerevisiae cAMP-dependent protein kinase controls entry into stationary phase through the Rim15p protein kinase.

P51679	CCR4_HUMAN	C-C chemokine receptor type 4	7642634	Molecular cloning and functional expression of a novel CC chemokine receptor cDNA from a human basophilic cell line.

Q91399	ID3A_XENLA	DNA-binding protein inhibitor ID-3-A	19851287	Self-regulation of Stat3 activity coordinates cell-cycle progression and neural crest specification.

Q8CGS4	CHMP3_RAT	Charged multivesicular body protein 3	12878588	Identification of mammalian Vps24p as an effector of phosphatidylinositol 3,5-bisphosphate-dependent endosome compartmentalization.

Q6AWX6	SCAR1_ARATH	Protein SCAR1	17267444	The role of Arabidopsis SCAR genes in ARP2-ARP3-dependent cell morphogenesis.

Q29980	MICB_HUMAN	MHC class I polypeptide-related sequence B	11491531	Interactions of human NKG2D with its ligands MICA, MICB, and homologs of the mouse RAE-1 protein family.

P31269	HXA9_HUMAN	Homeobox protein Hox-A9	8563754	The t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP98 and class I homeoprotein HOXA9.

P65870	QUED_ECOLI	6-carboxy-5,6,7,8-tetrahydropterin synthase	19231875	Escherichia coli QueD is a 6-carboxy-5,6,7,8-tetrahydropterin synthase.

Q54K32	RGAA_DICDI	Ras GTPase-activating-like protein rgaA	11447112	Recruitment of cortexillin into the cleavage furrow is controlled by Rac1 and IQGAP-related proteins.

Q12905	ILF2_HUMAN	Interleukin enhancer-binding factor 2	7519613	Cloning and expression of cyclosporin A- and FK506-sensitive nuclear factor of activated T-cells: NF45 and NF90.

P32321	DCTD_HUMAN	Deoxycytidylate deaminase	7685356	Primary structure of human deoxycytidylate deaminase and overexpression of its functional protein in Escherichia coli.

Q9NR12	PDLI7_HUMAN	PDZ and LIM domain protein 7	7929196	LIM domain recognition of a tyrosine-containing tight turn.

Q9ZNV9	AHP1_ARATH	Histidine-containing phosphotransfer protein 1	11158442	Two types of putative nuclear factors that physically interact with histidine-containing phosphotransfer (Hpt) domains, signaling mediators in His-to-Asp phosphorelay, in Arabidopsis thaliana.

Q5T4F7	SFRP5_HUMAN	Secreted frizzled-related protein 5	10072424	Cloning and characterization of a secreted frizzled-related protein that is expressed by the retinal pigment epithelium.

Q9W6A6	OPSG4_DANRE	Green-sensitive opsin-4	10349976	Cloning and characterization of six zebrafish photoreceptor opsin cDNAs and immunolocalization of their corresponding proteins.

Q9Z1K5	ARI1_MOUSE	Protein ariadne-1 homolog	10431818	A family of structurally related RING finger proteins interacts specifically with the ubiquitin-conjugating enzyme UbcM4.

Q02574	MEC3_YEAST	DNA damage checkpoint control protein MEC3	16169844	The 9-1-1 checkpoint clamp physically interacts with polzeta and is partially required for spontaneous polzeta-dependent mutagenesis in Saccharomyces cerevisiae.

Q02892	NOG1_YEAST	Nucleolar GTP-binding protein 1	11112701	A novel nucleolar G-protein conserved in eukaryotes.

Q9VU58	NPLP2_DROME	Neuropeptide-like 2	12171930	Peptidomics of the larval Drosophila melanogaster central nervous system.

O94340	YHM7_SCHPO	Uncharacterized N-acetyltransferase C1271.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q13029	PRDM2_HUMAN	PR domain zinc finger protein 2	7538672	The retinoblastoma protein binds to RIZ, a zinc-finger protein that shares an epitope with the adenovirus E1A protein.

Q12468	CSN5_YEAST	COP9 signalosome complex subunit 5	12186635	Conservation of the COP9/signalosome in budding yeast.

P35527	K1C9_HUMAN	Keratin, type I cytoskeletal 9	10218578	Demonstration of the pathogenic effect of point mutated keratin 9 in vivo.

Q08023	FMP25_YEAST	Protein FMP25, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q8IX03	KIBRA_HUMAN	Protein KIBRA	18596123	KIBRA modulates directional migration of podocytes.

P05106	ITB3_HUMAN	Integrin beta-3	16051604	Cartilage oligomeric matrix protein/thrombospondin 5 supports chondrocyte attachment through interaction with integrins.

Q9UQ13	SHOC2_HUMAN	Leucine-rich repeat protein SHOC-2	9618511	Soc-2 encodes a leucine-rich repeat protein implicated in fibroblast growth factor receptor signaling.

O35878	HSPB2_RAT	Heat shock protein beta-2	9344664	Identification and characterization of the gene encoding a new member of the alpha-crystallin/small hsp family, closely linked to the alphaB-crystallin gene in a head-to-head manner.

Q13435	SF3B2_HUMAN	Splicing factor 3B subunit 2	8566756	Evidence that sequence-independent binding of highly conserved U2 snRNP proteins upstream of the branch site is required for assembly of spliceosomal complex A.

O88181	BARH2_RAT	BarH-like 2 homeobox protein	9698441	Mammalian BarH homologue is a potential regulator of neural bHLH genes.

Q9H9Z2	LN28A_HUMAN	Protein lin-28 homolog A	18951094	Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA.

P14682	UBC3_YEAST	Ubiquitin-conjugating enzyme E2-34 kDa	2842867	The yeast cell cycle gene CDC34 encodes a ubiquitin-conjugating enzyme.

Q62834	CD123_RAT	Cell division cycle protein 123 homolog	11699637	Reversion of temperature-sensitive mutation by inhibition of proteasome-mediated degradation of mutated D123 protein.

Q9PVY8	FXC2B_XENLA	Forkhead box protein C2-B	15656969	Of fox and frogs: fox (fork head/winged helix) transcription factors in Xenopus development.

Q6R327	RICTR_HUMAN	Rapamycin-insensitive companion of mTOR	15718470	Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex.

O94650	HUB1_SCHPO	Ubiquitin-like modifier hub1	15569151	Hub1 is an essential ubiquitin-like protein without functioning as a typical modifier in fission yeast.

P32604	F26_YEAST	Fructose-2,6-bisphosphatase	1322693	The yeast FBP26 gene codes for a fructose-2,6-bisphosphatase.

Q9P6J0	YHDC_SCHPO	Uncharacterized transporter C1683.12	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P55034	PSMD4_ARATH	26S proteasome non-ATPase regulatory subunit 4	17971041	26S proteasome regulatory particle mutants have increased oxidative stress tolerance.

Q9Z2Y0	KEG1_RAT	Glycine N-acyltransferase-like protein Keg1	10194414	HP33: hepatocellular carcinoma-enriched 33-kDa protein with similarity to mitochondrial N-acyltransferase but localized in a microtubule-dependent manner at the centrosome.

Q03778	RIFK_YEAST	Riboflavin kinase	10887197	Molecular characterization of FMN1, the structural gene for the monofunctional flavokinase of Saccharomyces cerevisiae.

Q9XJ27	RR9_ARATH	30S ribosomal protein S9, chloroplastic	10359080	A novel plant nuclear gene encoding chloroplast ribosomal protein S9 has a transit peptide related to that of rice chloroplast ribosomal protein L12.

P45973	CBX5_HUMAN	Chromobox protein homolog 5	15502821	A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1.

Q6T3U3	NPCL1_RAT	Niemann-Pick C1-like protein 1	15928087	The target of ezetimibe is Niemann-Pick C1-like 1 (NPC1L1).

P96796	HDRE_METBF	CoB--CoM heterodisulfide reductase subunit E	8174566	Purification of a two-subunit cytochrome-b-containing heterodisulfide reductase from methanol-grown Methanosarcina barkeri.

O60840	CAC1F_HUMAN	Voltage-dependent L-type calcium channel subunit alpha-1F	9662399	An L-type calcium-channel gene mutated in incomplete X-linked congenital stationary night blindness.

Q9Y256	FACE2_HUMAN	CAAX prenyl protease 2	10085068	Cloning and characterization of a mammalian prenyl protein-specific protease.

P62834	RAP1A_HUMAN	Ras-related protein Rap-1A	8756332	Ras/Rap effector specificity determined by charge reversal.

Q9M384	SCR_ARATH	Protein SCARECROW	8756724	The SCARECROW gene regulates an asymmetric cell division that is essential for generating the radial organization of the Arabidopsis root.

O43719	HTSF1_HUMAN	HIV Tat-specific factor 1	10454543	Tat-SF1 protein associates with RAP30 and human SPT5 proteins.

P53687	HST3_YEAST	NAD-dependent histone deacetylase HST3	7498786	The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability.

Q8K3A2	TRPT1_MOUSE	tRNA 2'-phosphotransferase 1	9826666	A functional homolog of a yeast tRNA splicing enzyme is conserved in higher eukaryotes and in Escherichia coli.

P46875	ATK3_ARATH	Kinesin-3	8075402	Sequencing and characterization of the kinesin-related genes katB and katC of Arabidopsis thaliana.

Q969Q1	TRI63_HUMAN	E3 ubiquitin-protein ligase TRIM63	11927605	Muscle-specific RING finger-1 interacts with titin to regulate sarcomeric M-line and thick filament structure and may have nuclear functions via its interaction with glucocorticoid modulatory element binding protein-1.

P38348	HSM3_YEAST	DNA mismatch repair protein HSM3	19412159	Chaperone-mediated pathway of proteasome regulatory particle assembly.

P09556	PYR5_DICDI	Uridine 5'-monophosphate synthase	2835631	Sequence analysis of the DdPYR5-6 gene coding for UMP synthase in Dictyostelium discoideum and comparison with orotate phosphoribosyl transferases and OMP decarboxylases.

Q8LBA6	PIS1_ARATH	CDP-diacylglycerol--inositol 3-phosphatidyltransferase 1	10809447	Cloning of Arabidopsis thaliana phosphatidylinositol synthase and functional expression in the yeast pis mutant.

Q9FKA7	ORTH1_ARATH	E3 ubiquitin-protein ligase ORTHRUS 1	18704160	Three SRA-domain methylcytosine-binding proteins cooperate to maintain global CpG methylation and epigenetic silencing in Arabidopsis.

P38433	ACE1_CAEEL	Acetylcholinesterase 1	8144590	cDNA sequence, gene structure, and in vitro expression of ace-1, the gene encoding acetylcholinesterase of class A in the nematode Caenorhabditis elegans.

P43308	SSRB_HUMAN	Translocon-associated protein subunit beta	7789174	Isolation and mapping of the human beta-signal sequence receptor gene (SSR2).

P32361	IRE1_YEAST	Serine/threonine-protein kinase/endoribonuclease IRE1	9323131	The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response.

Q9ZR72	AB1B_ARATH	ABC transporter B family member 1	16212599	Cellular efflux of auxin catalyzed by the Arabidopsis MDR/PGP transporter AtPGP1.

Q07869	PPARA_HUMAN	Peroxisome proliferator-activated receptor alpha	12955147	Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-alpha.

Q7SIG4	DFPA_LOLVU	Diisopropyl-fluorophosphatase	15966726	Mutational and structural studies of the diisopropylfluorophosphatase from Loligo vulgaris shed new light on the catalytic mechanism of the enzyme.

P03874	CBP2_YEAST	Cytochrome B pre-mRNA-processing protein 2	9092668	The Cbp2 protein stimulates the splicing of the omega intron of yeast mitochondria.

P40452	COA1_YEAST	Cytochrome oxidase assembly protein 1	17882259	Shy1 couples Cox1 translational regulation to cytochrome c oxidase assembly.

O74835	RRP5_SCHPO	rRNA biogenesis protein rrp5	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

A2AI08	TPRN_MOUSE	Taperin	20170899	Targeted capture and next-generation sequencing identifies C9orf75, encoding taperin, as the mutated gene in nonsyndromic deafness DFNB79.

P06400	RB_HUMAN	Retinoblastoma-associated protein	16360038	Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release.

Q93Y52	IPYR1_CHLRE	Soluble inorganic pyrophosphatase 1, chloroplastic	16313235	A novel subfamily of monomeric inorganic pyrophosphatases in photosynthetic eukaryotes.

O97148	MTH_DROME	G-protein coupled receptor Mth	19672878	The Drosophila G protein-coupled receptor, Methuselah, exhibits a promiscuous response to peptides.

P83291	NCB5R_ARATH	NADH-cytochrome b5 reductase-like protein	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

O82302	P2C29_ARATH	Protein phosphatase 2C 29	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P32056	NUDD_ECOLI	GDP-mannose mannosyl hydrolase	7592609	A novel GDP-mannose mannosyl hydrolase shares homology with the MutT family of enzymes.

O42883	YFQ6_SCHPO	Uncharacterized protein C8E11.06	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Y7P9	YQ65_SCHPO	Uncharacterized protein C191.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q94JM3	ARFB_ARATH	Auxin response factor 2	9188533	ARF1, a transcription factor that binds to auxin response elements.

Q6P549	SHIP2_MOUSE	Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2	15654325	Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity.

A4LBC0	LFL1_ORYSJ	B3 domain-containing protein LFL1	17592727	Ectopic expression of OsLFL1 in rice represses Ehd1 by binding on its promoter.

P47224	MSS4_HUMAN	Guanine nucleotide exchange factor MSS4	9441742	Cloning of novel transcripts of the human guanine-nucleotide-exchange factor Mss4: in situ chromosomal mapping and expression in pancreatic cancer.

Q91V45	KISSR_MOUSE	KiSS-1 receptor	12359743	Identification and characterization of mouse metastasis-suppressor KiSS1 and its G-protein-coupled receptor.

Q08043	ACTN3_HUMAN	Alpha-actinin-3	11171996	Myozenin: an alpha-actinin- and gamma-filamin-binding protein of skeletal muscle Z lines.

P55884	EIF3B_HUMAN	Eukaryotic translation initiation factor 3 subunit B	18599441	Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3.

Q9SYK4	IP5PD_ARATH	Type I inositol-1,4,5-trisphosphate 5-phosphatase 13	18252844	An inositol polyphosphate 5-phosphatase functions in PHOTOTROPIN1 signaling in Arabidopis by altering cytosolic Ca2+.

Q80Z64	NANOG_MOUSE	Homeobox protein NANOG	16801560	Nanog binds to Smad1 and blocks bone morphogenetic protein-induced differentiation of embryonic stem cells.

Q10414	MU161_SCHPO	CWF19-like protein mug161	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q91ZK4	DMBX1_MOUSE	Diencephalon/mesencephalon homeobox protein 1	15314164	Neonatal lethality, dwarfism, and abnormal brain development in Dmbx1 mutant mice.

Q80ZA0	ITL1B_MOUSE	Intelectin-1b	17420014	Nippostrongylus brasiliensis: identification of intelectin-1 and -2 as Stat6-dependent genes expressed in lung and intestine during infection.

Q924A4	UCN3_MOUSE	Urocortin-3	11416224	Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor.

P85067	OJP1_SEPOF	Ovarian jelly-peptide 1	16434122	Ovarian jelly-peptides (OJPs), a new family of regulatory peptides identified in the cephalopod Sepia officinalis.

Q9VS97	PGPSD_DROME	Peptidoglycan-recognition protein SD	15448690	Function of the Drosophila pattern-recognition receptor PGRP-SD in the detection of Gram-positive bacteria.

Q15022	SUZ12_HUMAN	Polycomb protein SUZ12	15385962	Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity.

Q19203	UNC98_CAEEL	Zinc finger protein unc-98	7348600	Identification of genetic elements associated with muscle structure in the nematode Caenorhabditis elegans.

O88572	LRP6_MOUSE	Low-density lipoprotein receptor-related protein 6	17376403	GRB10 binds to LRP6, the Wnt co-receptor and inhibits canonical Wnt signaling pathway.

O94615	YBK6_SCHPO	Uncharacterized protein C1289.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q6PQK2	NP7_RHOPR	Nitrophorin-7	17428677	Overexpression in Escherichia coli and functional reconstitution of the liposome binding ferriheme protein nitrophorin 7 from the bloodsucking bug Rhodnius prolixus.

Q9Y2Y0	AR2BP_HUMAN	ADP-ribosylation factor-like protein 2-binding protein	10488091	The ARF-like 2 (ARL2)-binding protein, BART. Purification, cloning, and initial characterization.

Q16206	ENOX2_HUMAN	Ecto-NOX disulfide-thiol exchanger 2	12356293	Biochemical basis for the biological clock.

Q04437	KU80_YEAST	ATP-dependent DNA helicase II subunit 2	14551211	Separation-of-function mutants of yeast Ku80 reveal a Yku80p-Sir4p interaction involved in telomeric silencing.

Q3LH63	DMRT1_XENLA	Doublesex- and mab-3-related transcription factor 1	15988164	Molecular cloning of Dmrt1 and its expression in the gonad of Xenopus.

Q5SQX6	CYFP2_MOUSE	Cytoplasmic FMR1-interacting protein 2	11438699	A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P.

O00187	MASP2_HUMAN	Mannan-binding lectin serine protease 2	10946292	Proteolytic activities of two types of mannose-binding lectin- associated serine protease.

Q9Y5K6	CD2AP_HUMAN	CD2-associated protein	10339567	CMS: an adapter molecule involved in cytoskeletal rearrangements.

Q15109	RAGE_HUMAN	Advanced glycosylation end product-specific receptor	19386136	Both Ca2+ and Zn2+ are essential for S100A12 protein oligomerization and function.

Q9M066	C90C1_ARATH	3-epi-6-deoxocathasterone 23-monooxygenase	15703058	CYP90C1 and CYP90D1 are involved in different steps in the brassinosteroid biosynthesis pathway in Arabidopsis thaliana.

Q9JKF0	TR123_RAT	Taste receptor type 2 member 123	10761934	A novel family of mammalian taste receptors.

O04318	NSP3_ARATH	Nitrile-specifier protein 3	18987211	The genetic basis of constitutive and herbivore-induced ESP- independent nitrile formation in Arabidopsis.

P12686	RT13_YEAST	37S ribosomal protein MRP13, mitochondrial	9151978	Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae.

Q9Y091	FL2D_DROME	Pre-mRNA-splicing regulator female-lethal(2)D	12444081	Biochemical function of female-lethal (2)D/Wilms' tumor suppressor-1- associated proteins in alternative pre-mRNA splicing.

Q9Z2V5	HDAC6_MOUSE	Histone deacetylase 6	9891014	Identification of a new family of higher eukaryotic histone deacetylases. Coordinate expression of differentiation-dependent chromatin modifiers.

Q9ZUH4	MYRS1_ARATH	Myrcene/ocimene synthase 1, chloroplastic	10700382	Terpenoid secondary metabolism in Arabidopsis thaliana: cDNA cloning, characterization, and functional expression of a myrcene/(E)-beta- ocimene synthase.

Q92974	ARHG2_HUMAN	Rho guanine nucleotide exchange factor 2	11912491	Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton.

Q9LKJ1	HIBC1_ARATH	3-hydroxyisobutyryl-CoA hydrolase 1	19529827	Disruption of Arabidopsis CHY1 reveals an important role of metabolic status in plant cold stress signaling.

O15296	LX15B_HUMAN	Arachidonate 15-lipoxygenase B	11839751	Evidence that arachidonate 15-lipoxygenase 2 is a negative cell cycle regulator in normal prostate epithelial cells.

Q06631	BFR2_YEAST	Protein BFR2	14562095	Global analysis of protein localization in budding yeast.

P20052	PHO80_YEAST	PHO85 cyclin PHO80	9853758	The receptor Msn5 exports the phosphorylated transcription factor Pho4 out of the nucleus.

Q9SCZ4	FERON_ARATH	Receptor-like protein kinase FERONIA	19383785	Three related receptor-like kinases are required for optimal cell elongation in Arabidopsis thaliana.

Q9ULV3	CIZ1_HUMAN	Cip1-interacting zinc finger protein	10529385	Cloning and characterization of a novel p21(Cip1/Waf1)-interacting zinc finger protein, ciz1.

O95236	APOL3_HUMAN	Apolipoprotein L3	10233894	Vascular endothelial genes that are responsive to tumor necrosis factor-alpha in vitro are expressed in atherosclerotic lesions, including inhibitor of apoptosis protein-1, stannin, and two novel genes.

P63004	LIS1_RAT	Platelet-activating factor acetylhydrolase IB subunit alpha	11056532	A role for the lissencephaly gene LIS1 in mitosis and cytoplasmic dynein function.

P47057	SNX4_YEAST	Sorting nexin-4	12554655	Retromer and the sorting nexins Snx4/41/42 mediate distinct retrieval pathways from yeast endosomes.

Q00911	EGR4_RAT	Early growth response protein 4	2072895	The early response gene NGFI-C encodes a zinc finger transcriptional activator and is a member of the GCGGGGGCG (GSG) element-binding protein family.

P41182	BCL6_HUMAN	B-cell lymphoma 6 protein	16455075	Plastic downregulation of the transcriptional repressor BCL6 during maturation of human dendritic cells.

O35082	KLOT_MOUSE	Klotho	9363890	Mutation of the mouse klotho gene leads to a syndrome resembling ageing.

P28039	AOAH_HUMAN	Acyloxyacyl hydrolase	1883828	Expression and characterization of recombinant human acyloxyacyl hydrolase, a leukocyte enzyme that deacylates bacterial lipopolysaccharides.

Q9BV73	CP250_HUMAN	Centrosome-associated protein CEP250	9647649	C-Nap1, a novel centrosomal coiled-coil protein and candidate substrate of the cell cycle-regulated protein kinase Nek2.

P55061	BI1_HUMAN	Bax inhibitor 1	8530040	Identification of a novel conserved human gene, TEGT.

P38114	TBS1_YEAST	Uncharacterized transcriptional regulatory protein TBS1	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Q9URY7	FMDA_SCHPO	Putative formamidase C869.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8IV16	HDBP1_HUMAN	Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1	17997385	Normal binding of lipoprotein lipase, chylomicrons, and apo-AV to GPIHBP1 containing a G56R amino acid substitution.

O14965	STK6_HUMAN	Serine/threonine-protein kinase 6	14603251	TACC1-chTOG-Aurora A protein complex in breast cancer.

P54274	TERF1_HUMAN	Telomeric repeat-binding factor 1	11943150	Involvement of the telomeric protein Pin2/TRF1 in the regulation of the mitotic spindle.

Q9W539	HR4_DROME	Hormone receptor 4	15935763	The ecdysone-induced DHR4 orphan nuclear receptor coordinates growth and maturation in Drosophila.

Q27272	TAF9_DROME	Transcription initiation factor TFIID subunit 9	11438676	The novel transcription factor e(y)2 interacts with TAF(II)40 and potentiates transcription activation on chromatin templates.

P78831	GHT5_SCHPO	High-affinity glucose transporter ght5	10735857	Multiple hexose transporters of Schizosaccharomyces pombe.

Q32NK7	OSR2A_XENLA	Protein odd-skipped-related 2-A	17011543	Odd-skipped genes encode repressors that control kidney development.

Q8IFN0	YD115_PLAF7	Uncharacterized protein PFD1115c	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

P46063	RECQ1_HUMAN	ATP-dependent DNA helicase Q1	7527136	Molecular cloning of cDNA encoding human DNA helicase Q1 which has homology to Escherichia coli Rec Q helicase and localization of the gene at chromosome 12p12.

Q03557	GATH_YEAST	Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial	19417106	Yeast mitochondrial Gln-tRNA(Gln) is generated by a GatFAB-mediated transamidation pathway involving Arc1p-controlled subcellular sorting of cytosolic GluRS.

O81057	ASK14_ARATH	SKP1-like protein 14	19682297	An F-box gene, CPR30, functions as a negative regulator of the defense response in Arabidopsis.

P22071	3BHS1_RAT	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1	1955079	3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase expression in rat and characterization of the testis isoform.

Q63117	CLK3_RAT	Dual specificity protein kinase CLK3	8679717	cDNA cloning and characterization of rat Clk3, a LAMMER kinase predominately expressed in testis.

Q2PG84	SOX1_XENLA	Transcription factor Sox-1	17056008	Expression of Sox1 during Xenopus early embryogenesis.

Q9NRM6	I17RB_HUMAN	Interleukin-17 receptor B	10749887	A novel cytokine receptor-ligand pair. Identification, molecular characterization, and in vivo immunomodulatory activity.

P16870	CBPE_HUMAN	Carboxypeptidase E	2334405	Human carboxypeptidase E. Isolation and characterization of the cDNA, sequence conservation, expression and processing in vitro.

Q15042	RB3GP_HUMAN	Rab3 GTPase-activating protein catalytic subunit	9030515	Isolation and characterization of a GTPase activating protein specific for the Rab3 subfamily of small G proteins.

Q9UT27	PVG1_SCHPO	Pyruvyl transferase 1	15173185	Five genes involved in biosynthesis of the pyruvylated Galbeta1,3- epitope in Schizosaccharomyces pombe N-linked glycans.

Q9Y5J5	PHLA3_HUMAN	Pleckstrin homology-like domain family A member 3	10594239	A novel pleckstrin homology-related gene family defined by Ipl/Tssc3, TDAG51, and Tih1: tissue-specific expression, chromosomal location, and parental imprinting.

Q9UW14	PACC_CANAL	pH-response transcription factor pacC/RIM101	10848590	Dominant active alleles of RIM101 (PRR2) bypass the pH restriction on filamentation of Candida albicans.

O15516	CLOCK_HUMAN	Circadian locomoter output cycles protein kaput	10198158	Molecular cloning and characterization of the human CLOCK gene: expression in the suprachiasmatic nuclei.

Q8WWM7	ATX2L_HUMAN	Ataxin-2-like protein	11784712	Cloning and characterization of a family of proteins associated with Mpl.

Q13410	BT1A1_HUMAN	Butyrophilin subfamily 1 member A1	8611614	Cloning and sequence analysis of human butyrophilin reveals a potential receptor function.

P61812	TGFB2_HUMAN	Transforming growth factor beta-2	17827158	Mechanisms for asporin function and regulation in articular cartilage.

Q64092	TFE3_MOUSE	Transcription factor E3	16936731	Transcription factors TFE3 and TFEB are critical for CD40 ligand expression and thymus-dependent humoral immunity.

P08123	CO1A2_HUMAN	Collagen alpha-2(I) chain	6267597	Cloning a cDNA for the pro-alpha 2 chain of human type I collagen.

O35217	MINP1_RAT	Multiple inositol polyphosphate phosphatase 1	9359836	Molecular cloning and expression of a rat hepatic multiple inositol polyphosphate phosphatase.

Q16610	ECM1_HUMAN	Extracellular matrix protein 1	12604605	Perlecan protein core interacts with extracellular matrix protein 1 (ECM1), a glycoprotein involved in bone formation and angiogenesis.

Q7KU24	CHD1_DROME	Chromodomain-helicase-DNA-binding protein 1	17717186	CHD1 motor protein is required for deposition of histone variant H3.3 into chromatin in vivo.

Q9W0W6	NPLP1_DROME	Neuropeptide-like 1	12171930	Peptidomics of the larval Drosophila melanogaster central nervous system.

P32790	SLA1_YEAST	Actin cytoskeleton-regulatory complex protein SLA1	10198057	Sla1p is a functionally modular component of the yeast cortical actin cytoskeleton required for correct localization of both Rho1p-GTPase and Sla2p, a protein with talin homology.

P63004	LIS1_RAT	Platelet-activating factor acetylhydrolase IB subunit alpha	11001923	Interaction between LIS1 and doublecortin, two lissencephaly gene products.

P53389	HOL1_YEAST	Protein HOL1	8955402	Amino acid substitutions in membrane-spanning domains of Hol1, a member of the major facilitator superfamily of transporters, confer nonselective cation uptake in Saccharomyces cerevisiae.

P07266	MRS1_YEAST	Mitochondrial RNA-splicing protein MRS1	11773622	Recruitment of intron-encoded and co-opted proteins in splicing of the bI3 group I intron RNA.

P55089	UCN1_HUMAN	Urocortin	8612563	Cloning and characterization of human urocortin.

Q7TN45	MRGB4_RAT	Mas-related G-protein coupled receptor member B4	12909716	Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family.

Q9QY15	DDX25_MOUSE	ATP-dependent RNA helicase DDX25	16968703	Gonadotropin-regulated testicular RNA helicase (GRTH/Ddx25) is a transport protein involved in gene-specific mRNA export and protein translation during spermatogenesis.

P78545	ELF3_HUMAN	ETS-related transcription factor Elf-3	10391676	Exon 4-encoded acidic domain in the epithelium-restricted Ets factor, ESX, confers potent transactivating capacity and binds to TATA-binding protein (TBP).

O14763	TR10B_HUMAN	Tumor necrosis factor receptor superfamily member 10B	9311998	TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL.

Q9NPB9	CCRL1_HUMAN	C-C chemokine receptor type 11	10734104	CCR11 is a functional receptor for the monocyte chemoattractant protein family of chemokines.

O94546	MU150_SCHPO	Meiotically up-regulated gene 150 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P53813	PROS_RAT	Vitamin K-dependent protein S	7608128	Molecular cloning and functional characterization of rat plasma protein S.

O00308	WWP2_HUMAN	NEDD4-like E3 ubiquitin-protein ligase WWP2	12450395	Adenovirus protein involved in virus internalization recruits ubiquitin-protein ligases.

Q09028	RBBP4_HUMAN	Histone-binding protein RBBP4	9150135	Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex.

Q9CXY6	ILF2_MOUSE	Interleukin enhancer-binding factor 2	11804788	Ilf2 is regulated during meiosis and associated to transcriptionally active chromatin.

Q9FLT2	IPMKB_ARATH	Inositol polyphosphate multikinase beta	12566584	Arabidopsis inositol polyphosphate 6-/3-kinase is a nuclear protein that complements a yeast mutant lacking a functional ArgR-Mcm1 transcription complex.

Q9Z340	PARD3_RAT	Partitioning defective 3 homolog	18550519	Par-3-mediated junctional localization of the lipid phosphatase PTEN is required for cell polarity establishment.

P53141	MLC1_YEAST	Myosin light chain 1	11082046	Yeast myosin light chain, Mlc1p, interacts with both IQGAP and class II myosin to effect cytokinesis.

Q9XTJ4	NHR3_CAEEL	Nuclear hormone receptor family member nhr-3	10022975	The nuclear receptor superfamily has undergone extensive proliferation and diversification in nematodes.

Q9UKY7	CDV3_HUMAN	Protein CDV3 homolog	10497265	Identification of differentially expressed genes associated with HER- 2/neu overexpression in human breast cancer cells.

P97953	VEGFC_MOUSE	Vascular endothelial growth factor C	9012504	VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development.

P14906	SEC63_YEAST	Protein translocation protein SEC63	2000150	Assembly of yeast Sec proteins involved in translocation into the endoplasmic reticulum into a membrane-bound multisubunit complex.

Q8K1S7	KREM2_MOUSE	Kremen protein 2	16531414	The MRH protein Erlectin is a member of the endoplasmic reticulum synexpression group and functions in N-glycan recognition.

Q9VJQ5	NC2B_DROME	Protein Dr1	11062130	A basal transcription factor that activates or represses transcription.

Q9JIL8	RAD50_RAT	DNA repair protein RAD50	10908350	The MRE11-NBS1-RAD50 pathway is perturbed in SV40 large T antigen- immortalized AT-1, AT-2 and HL-1 cardiomyocytes.

Q9P783	RRB1_SCHPO	Ribosome assembly protein rrb1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9BYV7	BCDO2_HUMAN	Beta,beta-carotene 9',10'-oxygenase	11278918	Identification and characterization of a mammalian enzyme catalyzing the asymmetric oxidative cleavage of provitamin A.

P60651	SPEB_ECOLI	Agmatinase	10329468	Manganese is essential for catalytic activity of Escherichia coli agmatinase.

Q05930	MDM30_YEAST	Mitochondrial distribution and morphology protein 30	12808031	Mdm30 is an F-box protein required for maintenance of fusion- competent mitochondria in yeast.

Q9VC57	ATLAS_DROME	Atlastin	17030474	Loss of spastic paraplegia gene atlastin induces age-dependent death of dopaminergic neurons in Drosophila.

P13635	CERU_RAT	Ceruloplasmin	2332446	Primary structure of rat ceruloplasmin and analysis of tissue- specific gene expression during development.

P28518	XPA_DROME	DNA repair protein complementing XP-A cells homolog	7673233	Expression and functional analyses of the Dxpa gene, the Drosophila homolog of the human excision repair gene XPA.

P84196	GUNB_GLOTR	Endoglucanase Cel12A	15870328	Processive endoglucanase active in crystalline cellulose hydrolysis by the brown rot basidiomycete Gloeophyllum trabeum.

Q8IXI2	MIRO1_HUMAN	Mitochondrial Rho GTPase 1	12482879	Atypical Rho GTPases have roles in mitochondrial homeostasis and apoptosis.

P40090	SCC4_YEAST	Sister chromatid cohesion protein 4	10882066	Cohesin's binding to chromosomes depends on a separate complex consisting of Scc2 and Scc4 proteins.

Q9VFJ3	HTRA2_DROME	Serine protease HTRA2, mitochondrial	18259196	The interaction of DIAP1 with dOmi/HtrA2 regulates cell death in Drosophila.

Q9NYW5	TA2R4_HUMAN	Taste receptor type 2 member 4	10761934	A novel family of mammalian taste receptors.

Q8VZG8	Y4885_ARATH	Probable LRR receptor-like serine/threonine-protein kinase At4g08850	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

P40993	RMRP_YEAST	Ribonuclease MRP protein subunit SNM1	7958920	Characterization of a unique protein component of yeast RNase MRP: an RNA-binding protein with a zinc-cluster domain.

P15514	AREG_HUMAN	Amphiregulin	3413110	Amphiregulin: a bifunctional growth-modulating glycoprotein produced by the phorbol 12-myristate 13-acetate-treated human breast adenocarcinoma cell line MCF-7.

Q9GZR5	ELOV4_HUMAN	Elongation of very long chain fatty acids protein 4	11138005	A 5-bp deletion in ELOVL4 is associated with two related forms of autosomal dominant macular dystrophy.

Q16082	HSPB2_HUMAN	Heat shock protein beta-2	9344664	Identification and characterization of the gene encoding a new member of the alpha-crystallin/small hsp family, closely linked to the alphaB-crystallin gene in a head-to-head manner.

P11362	FGFR1_HUMAN	Basic fibroblast growth factor receptor 1	7874169	A common mutation in the fibroblast growth factor receptor 1 gene in Pfeiffer syndrome.

Q75Q39	TOM70_RAT	Mitochondrial import receptor subunit TOM70	11956321	Characterization of rat TOM70 as a receptor of the preprotein translocase of the mitochondrial outer membrane.

P38631	FKS1_YEAST	1,3-beta-glucan synthase component FKS1	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

O14975	S27A2_HUMAN	Very long-chain acyl-CoA synthetase	10198260	Human very-long-chain acyl-CoA synthetase: cloning, topography, and relevance to branched-chain fatty acid metabolism.

P55266	DSRAD_RAT	Double-stranded RNA-specific adenosine deaminase	7862132	Cloning of cDNAs encoding mammalian double-stranded RNA-specific adenosine deaminase.

O89093	CCL20_MOUSE	C-C motif chemokine 20	9862452	Molecular cloning, functional characterization and mRNA expression analysis of the murine chemokine receptor CCR6 and its specific ligand MIP-3alpha.

P06780	RHO1_YEAST	GTP-binding protein RHO1	8602515	Identification of yeast Rho1p GTPase as a regulatory subunit of 1,3- beta-glucan synthase.

O43490	PROM1_HUMAN	Prominin-1	12042327	AC133-2, a novel isoform of human AC133 stem cell antigen.

P63167	DYL1_HUMAN	Dynein light chain 1, cytoplasmic	16684779	Essential role of KIBRA in co-activator function of dynein light chain 1 in mammalian cells.

Q8R3P2	DTX2_MOUSE	Protein deltex-2	11226752	Murine homologs of deltex define a novel gene family involved in vertebrate Notch signaling and neurogenesis.

O88898	P63_MOUSE	Tumor protein 63	10227293	p63 is a p53 homologue required for limb and epidermal morphogenesis.

P49893	WN11B_XENLA	Protein Wnt-11b	15797385	Maternal wnt11 activates the canonical wnt signaling pathway required for axis formation in Xenopus embryos.

Q867Z4	LOLA4_DROME	Longitudinals lacking protein, isoforms F/I/K/T	8050351	Lola encodes a putative transcription factor required for axon growth and guidance in Drosophila.

P35180	TOM20_YEAST	Mitochondrial import receptor subunit TOM20	8223428	Functional cooperation of mitochondrial protein import receptors in yeast.

Q9Y2B5	CP007_HUMAN	Uncharacterized protein C16orf7	10231027	Isolation and mapping of putative b subunit of human ATPase (ATP-BL) from human leukocytes.

Q62018	CTR9_MOUSE	RNA polymerase-associated protein CTR9 homolog	8636124	p150TSP, a conserved nuclear phosphoprotein that contains multiple tetratricopeptide repeats and binds specifically to SH2 domains.

Q9H0H5	RGAP1_HUMAN	Rac GTPase-activating protein 1	12590651	Rho family GTPase Rnd2 interacts and co-localizes with MgcRacGAP in male germ cells.

Q9R229	BMP10_MOUSE	Bone morphogenetic protein 10	15073151	BMP10 is essential for maintaining cardiac growth during murine cardiogenesis.

P56589	PEX3_HUMAN	Peroxisomal biogenesis factor 3	10430017	Identification and characterization of the human peroxin PEX3.

O59719	YBHB_SCHPO	Uncharacterized protein C3B8.11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q60766	IRGM1_MOUSE	Immunity-related GTPase family M protein 1	11457893	Inactivation of LRG-47 and IRG-47 reveals a family of interferon gamma-inducible genes with essential, pathogen-specific roles in resistance to infection.

O93235	CIRBA_XENLA	Cold-inducible RNA-binding protein A	16600183	Cold-inducible RNA binding protein is required for the expression of adhesion molecules and embryonic cell movement in Xenopus laevis.

O15061	SYNEM_HUMAN	Synemin	16777071	Interactions of intermediate filament protein synemin with dystrophin and utrophin.

Q9NQE7	TSSP_HUMAN	Thymus-specific serine protease	10527559	Cloning of a novel MHC-encoded serine peptidase highly expressed by cortical epithelial cells of the thymus.

Q9FIK0	K6PF2_ARATH	6-phosphofructokinase 2	17485088	Characterisation of the ATP-dependent phosphofructokinase gene family from Arabidopsis thaliana.

P34761	WHI3_YEAST	Protein WHI3	11290704	Isolation and characterization of WHI3, a size-control gene of Saccharomyces cerevisiae.

P0ABH9	CLPA_ECOLI	ATP-dependent Clp protease ATP-binding subunit ClpA	12235156	Crystal structure of the heterodimeric complex of the adaptor, ClpS, with the N-domain of the AAA+ chaperone, ClpA.

Q684R7	FREM1_MOUSE	FRAS1-related extracellular matrix protein 1	15345741	The extracellular matrix gene Frem1 is essential for the normal adhesion of the embryonic epidermis.

Q96P20	NALP3_HUMAN	NACHT, LRR and PYD domains-containing protein 3	11786556	PYPAF1: a PYRIN-containing APAF1-like protein that assembles with ASC and activates NF-kB.

Q9SAF1	ARP3_ARATH	Actin-related protein 3	12837952	Mutations in actin-related proteins 2 and 3 affect cell shape development in Arabidopsis.

P16930	FAAA_HUMAN	Fumarylacetoacetase	1998338	Cloning and expression of the cDNA encoding human fumarylacetoacetate hydrolase, the enzyme deficient in hereditary tyrosinemia: assignment of the gene to chromosome 15.

O22446	HDA19_ARATH	Histone deacetylase 19	15749761	HISTONE DEACETYLASE19 is involved in jasmonic acid and ethylene signaling of pathogen response in Arabidopsis.

Q9QWL7	K1C17_MOUSE	Keratin, type I cytoskeletal 17	16710422	A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth.

P27476	NSR1_YEAST	Nuclear localization sequence-binding protein	7800479	Isolation and characterization of two Saccharomyces cerevisiae genes that encode proteins that bind to (TG1-3)n single strand telomeric DNA in vitro.

Q7L523	RRAGA_HUMAN	Ras-related GTP-binding protein A	9394008	RagA is a functional homologue of S. cerevisiae Gtr1p involved in the Ran/Gsp1-GTPase pathway.

Q03375	CWC21_YEAST	Pre-mRNA-splicing factor CWC21	11884590	Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

Q92212	STE20_CANAL	Serine/threonine-protein kinase CST20	8917571	Signal transduction through homologs of the Ste20p and Ste7p protein kinases can trigger hyphal formation in the pathogenic fungus Candida albicans.

P17181	INAR1_HUMAN	Interferon alpha/beta receptor 1	2153461	Genetic transfer of a functional human interferon alpha receptor into mouse cells: cloning and expression of its cDNA.

Q9VNS0	MAEL_DROME	Protein maelstrom	11277405	Maelstrom is required to position the MTOC in stage 2-6 Drosophila oocytes.

P23560	BDNF_HUMAN	Brain-derived neurotrophic factor	2236018	Molecular cloning of a human gene that is a member of the nerve growth factor family.

P21179	CATE_ECOLI	Catalase HPII	7663946	Crystal structure of catalase HPII from Escherichia coli.

Q09790	APS1_SCHPO	Diphosphoinositol polyphosphate phosphohydrolase aps1	12387729	Disruption and overexpression of the Schizosaccharomyces pombe aps1 gene, and effects on growth rate, morphology and intracellular diadenosine 5',5''-P1,P5-pentaphosphate and diphosphoinositol polyphosphate concentrations.

Q99836	MYD88_HUMAN	Myeloid differentiation primary response protein MyD88	16286016	IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST 2 and induces T helper type 2-associated cytokines.

P47794	CCNE1_DANRE	G1/S-specific cyclin-E1	9019240	Zebrafish cyclin E regulation during early embryogenesis.

Q9UQF0	ENW1_HUMAN	HERV-W_7q21.2 provirus ancestral Env polyprotein	10693809	Syncytin is captive retroviral envelope protein involved in human placental morphogenesis.

P38624	PSB6_YEAST	Proteasome component PRE3	9087403	Structure of 20S proteasome from yeast at 2.4-A resolution.

O96626	ARPC5_DICDI	Actin-related protein 2/3 complex subunit 5	17296313	Vectors for expression of proteins with single or combinatorial fluorescent protein and tandem affinity purification tags in Dictyostelium.

Q44339	FLGA_AGRT5	Flagellar protein flgA	9161424	Isolation and characterisation of a linked cluster of genes from Agrobacterium tumefaciens encoding proteins involved in flagellar basal-body structure.

Q8CDG1	PIWL2_MOUSE	Piwi-like protein 2	16751777	A novel class of small RNAs bind to MILI protein in mouse testes.

P60484	PTEN_HUMAN	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	9593664	The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate.

Q9ZUT3	ALS3_ARATH	Protein ALUMINUM SENSITIVE 3	12223767	Al inhibits both shoot development and root growth in als3, an Al- sensitive Arabidopsis mutant.

Q9NGJ7	CLC5_CAEEL	Clc-like protein 5	10395899	Identification and characterization of a new member of the gas3/PMP22 gene family in C. elegans.

Q08420	SODE_RAT	Extracellular superoxide dismutase [Cu-Zn]	8643556	The rat extracellular superoxide dismutase dimer is converted to a tetramer by the exchange of a single amino acid.

Q944A9	NPS11_ARATH	Novel plant SNARE 11	12068098	NPSN11 is a cell plate-associated SNARE protein that interacts with the syntaxin KNOLLE.

P18827	SDC1_HUMAN	Syndecan-1	2324102	Sequence of human syndecan indicates a novel gene family of integral membrane proteoglycans.

Q9C5X4	ATX1_ARATH	Histone-lysine N-methyltransferase ATX1	16585509	The Arabidopsis homolog of trithorax, ATX1, binds phosphatidylinositol 5-phosphate, and the two regulate a common set of target genes.

Q12051	GGPPS_YEAST	Geranylgeranyl pyrophosphate synthase	7665600	BTS1 encodes a geranylgeranyl diphosphate synthase in Saccharomyces cerevisiae.

O13995	DAP1_SCHPO	Cytochrome P450 regulator dap1	17276356	Dap1/PGRMC1 binds and regulates cytochrome P450 enzymes.

P46531	NOTC1_HUMAN	Neurogenic locus notch homolog protein 1	11101851	MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors.

O55162	LYPD3_RAT	Ly6/PLAUR domain-containing protein 3	15729693	Ly6 family member C4.4A binds laminins 1 and 5, associates with galectin-3 and supports cell migration.

Q93W77	NIFU1_ARATH	NifU-like protein 1, chloroplastic	15031412	The Arabidopsis chloroplastic NifU-like protein CnfU, which can act as an iron-sulfur cluster scaffold protein, is required for biogenesis of ferredoxin and photosystem I.

Q9QXT5	EGFL7_MOUSE	Epidermal growth factor-like protein 7	14592969	VE-statin, an endothelial repressor of smooth muscle cell migration.

Q53083	PSB2_RHOER	Proteasome subunit beta 2	7583123	The first characterization of a eubacterial proteasome: the 20S complex of Rhodococcus.

O00750	P3C2B_HUMAN	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit beta	10805725	Class II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptors.

Q9UHD2	TBK1_HUMAN	Serine/threonine-protein kinase TBK1	12692549	IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.

Q44458	FLIG_AGRT5	Flagellar motor switch protein FliG	9161425	The Agrobacterium tumefaciens motor gene, motA, is in a linked cluster with the flagellar switch protein genes, fliG, fliM and fliN.

Q8R2H3	BSND_RAT	Barttin	12111250	Barttin increases surface expression and changes current properties of ClC-K channels.

P53129	MON1_YEAST	Vacuolar fusion protein MON1	12364329	The Ccz1-Mon1 protein complex is required for the late step of multiple vacuole delivery pathways.

Q9VFS5	PP4R3_DROME	Serine/threonine-protein phosphatase 4 regulatory subunit 3	18487071	Depletion of protein phosphatase 4 in human cells reveals essential roles in centrosome maturation, cell migration and the regulation of Rho GTPases.

Q91ZP3	LPIN1_MOUSE	Phosphatidate phosphatase LPIN1	11138012	Lipodystrophy in the fld mouse results from mutation of a new gene encoding a nuclear protein, lipin.

Q8L5W8	PIL1_ARATH	Transcription factor PIL1	16891401	Functional profiling reveals that only a small number of phytochrome- regulated early-response genes in Arabidopsis are necessary for optimal deetiolation.

O94661	GYP10_SCHPO	GTPase-activating protein gyp10	16291723	Cell wall remodeling at the fission yeast cell division site requires the Rho-GEF Rgf3p.

Q92338	ABCI_SCHPO	Protein ABC1 homolog, mitochondrial	8668131	Cloning by functional complementation, and inactivation, of the Schizosaccharomyces pombe homologue of the Saccharomyces cerevisiae gene ABC1.

Q42484	RPS2_ARATH	Disease resistance protein RPS2	11333251	The leucine-rich repeat domain can determine effective interaction between RPS2 and other host factors in Arabidopsis RPS2-mediated disease resistance.

Q9UKA2	FBXL4_HUMAN	F-box/LRR-repeat protein 4	10531035	Identification of a family of human F-box proteins.

P38634	SIC1_YEAST	Protein SIC1	15448699	Hog1 mediates cell-cycle arrest in G1 phase by the dual targeting of Sic1.

P70662	LDB1_MOUSE	LIM domain-binding protein 1	9315627	Functional analysis of the nuclear LIM domain interactor NLI.

P10721	KIT_HUMAN	Mast/stem cell growth factor receptor	9438854	Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors.

P39301	ULAA_ECOLI	Ascorbate-specific permease IIC component ulaA	12644495	The ascorbate transporter of Escherichia coli.

Q8NER5	ACV1C_HUMAN	Activin receptor type-1C	15531507	Nodal induces apoptosis and inhibits proliferation in human epithelial ovarian cancer cells via activin receptor-like kinase 7.

Q16644	MAPK3_HUMAN	MAP kinase-activated protein kinase 3	10781029	Serine/Threonine kinases 3pK and MAPK-activated protein kinase 2 interact with the basic helix-loop-helix transcription factor E47 and repress its transcriptional activity.

Q09472	EP300_HUMAN	Histone acetyltransferase p300	11073990	A novel Rb- and p300-binding protein inhibits transactivation by MyoD.

Q99216	PNO1_YEAST	Pre-rRNA-processing protein PNO1	10923024	Functional analysis of six genes from chromosomes XIV and XV of Saccharomyces cerevisiae reveals YOR145c as an essential gene and YNL059c/ARP5 as a strain-dependent essential gene encoding nuclear proteins.

Q05902	ECM38_YEAST	Gamma-glutamyltransferase	6143574	Glutathione metabolism in yeast Saccharomyces cerevisiae. Evidence that gamma-glutamyltranspeptidase is a vacuolar enzyme.

P49768	PSN1_HUMAN	Presenilin-1	15274632	Purification and characterization of the human gamma-secretase complex.

Q8K3I6	IL27A_MOUSE	Interleukin-27 subunit alpha	12121660	IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4(+) T cells.

Q9GZN6	S6A16_HUMAN	Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5	11112352	Cloning and characterization of human NTT5 and v7-3: two orphan transporters of the Na(+)/Cl(-)-dependent neurotransmitter transporter gene family.

O94402	YQF9_SCHPO	Uncharacterized zinc transporter C126.09	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9BXR0	TGT_HUMAN	Queuine tRNA-ribosyltransferase	11255023	Characterization of cDNA encoding the human tRNA-guanine transglycosylase (TGT) catalytic subunit.

P06780	RHO1_YEAST	GTP-binding protein RHO1	8602514	Rho1p, a yeast protein at the interface between cell polarization and morphogenesis.

P08289	PPBT_RAT	Alkaline phosphatase, tissue-nonspecific isozyme	3422431	Structure and expression of rat osteosarcoma (ROS 17/2.8) alkaline phosphatase: product of a single copy gene.

Q0JQF7	DRE2A_ORYSJ	Dehydration-responsive element-binding protein 2A	12609047	OsDREB genes in rice, Oryza sativa L., encode transcription activators that function in drought-, high-salt- and cold-responsive gene expression.

Q9LK35	THE1_ARATH	Receptor-like protein kinase THESEUS 1	17540573	A receptor-like kinase mediates the response of Arabidopsis cells to the inhibition of cellulose synthesis.

P54733	CCNE_DROME	G1/S-specific cyclin-E	11565033	Archipelago regulates cyclin E levels in Drosophila and is mutated in human cancer cell lines.

Q93WX6	NFS2_ARATH	Cysteine desulfurase 2, chloroplastic	12427997	Characterization of a NifS-like chloroplast protein from Arabidopsis. Implications for its role in sulfur and selenium metabolism.

Q03096	EST3_YEAST	Telomere replication protein EST3	9382847	Programmed translational frameshifting in a gene required for yeast telomere replication.

Q9ESX4	NO40_MOUSE	Nucleolar protein of 40 kDa	12202495	Identification of ribosomal proteins specific to higher eukaryotic organisms.

P38623	RCK2_YEAST	Serine/threonine-protein kinase RCK2	14562095	Global analysis of protein localization in budding yeast.

P51801	CLCKB_HUMAN	Chloride channel protein ClC-Kb	8041726	Two highly homologous members of the ClC chloride channel family in both rat and human kidney.

Q5G872	SCUB2_DANRE	Signal peptide, CUB and EGF-like domain-containing protein 2	16626681	Scube2 mediates Hedgehog signalling in the zebrafish embryo.

Q09926	PCR1_SCHPO	Transcription factor pcr1	8552099	Schizosaccharomyces pombe pcr1+ encodes a CREB/ATF protein involved in regulation of gene expression for sexual development.

Q9VEC3	ARP5_DROME	Actin-related protein 5	16618800	A Polycomb group protein complex with sequence-specific DNA-binding and selective methyl-lysine-binding activities.

Q7YQK3	4F2_RABIT	4F2 cell-surface antigen heavy chain	12614332	Site-directed mutagenesis of rabbit LAT1 at amino acids 219 and 234.

Q9QYR7	ACOT3_MOUSE	Acyl-coenzyme A thioesterase 3	15007068	Molecular cloning and characterization of two mouse peroxisome proliferator-activated receptor alpha (PPARalpha)-regulated peroxisomal acyl-CoA thioesterases.

Q96LB8	PGRP4_HUMAN	Peptidoglycan recognition protein 4	17502600	Structural insights into the bactericidal mechanism of human peptidoglycan recognition proteins.

O95793	STAU1_HUMAN	Double-stranded RNA-binding protein Staufen homolog 1	19029303	Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs.

P04004	VTNC_HUMAN	Vitronectin	12808446	How vitronectin binds PAI-1 to modulate fibrinolysis and cell migration.

Q54RF4	CBP4A_DICDI	Calcium-binding protein 4a	15325281	Dictyostelium calcium-binding protein 4a interacts with nucleomorphin, a BRCT-domain protein that regulates nuclear number.

O74881	BTB1_SCHPO	BTB/POZ domain-containing protein 1	14527422	BTB/POZ domain proteins are putative substrate adaptors for cullin 3 ubiquitin ligases.

Q8MN58	CLC_DICDI	Clathrin light chain	16734666	Clathrin light chain: importance of the conserved carboxy terminal domain to function in living cells.

O04425	FCA_ARATH	Flowering time control protein FCA	17916737	Widespread role for the flowering-time regulators FCA and FPA in RNA- mediated chromatin silencing.

O74830	YC12_SCHPO	Putative glutathione S-transferase C1183.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q3UPW2	ELF3_MOUSE	ETS-related transcription factor Elf-3	9806763	The epithelium-specific ets transcription factor ESX is associated with mammary gland development and involution.

Q9EQJ4	ZN384_RAT	Zinc finger protein 384	10669742	CIZ, a zinc finger protein that interacts with p130cas and activates the expression of matrix metalloproteinases.

O95452	CXB6_HUMAN	Gap junction beta-6 protein	10610709	Human connexin 30 (GJB6), a candidate gene for nonsyndromic hearing loss: molecular cloning, tissue-specific expression, and assignment to chromosome 13q12.

Q9S7I6	RPK2_ARATH	LRR receptor-like serine/threonine-protein kinase RPK2	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q8T4F7	ENA_DROME	Protein enabled	10892742	Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the roundabout receptor.

Q7TQH7	LRP10_MOUSE	Low-density lipoprotein receptor-related protein 10	11123907	A novel low-density lipoprotein receptor-related protein mediating cellular uptake of apolipoprotein E-enriched beta-VLDL in vitro.

P40017	YAT2_YEAST	Carnitine O-acetyltransferase YAT2	14562095	Global analysis of protein localization in budding yeast.

P54257	HAP1_HUMAN	Huntingtin-associated protein 1	7477378	A huntingtin-associated protein enriched in brain with implications for pathology.

Q9UKL2	O52A1_HUMAN	Olfactory receptor 52A1	10512676	An olfactory receptor gene is located in the extended human beta- globin gene cluster and is expressed in erythroid cells.

Q9VDY1	INO80_DROME	Putative DNA helicase Ino80	16618800	A Polycomb group protein complex with sequence-specific DNA-binding and selective methyl-lysine-binding activities.

Q91XC0	JUB_MOUSE	Protein ajuba	15728191	The LIM protein Ajuba influences p130Cas localization and Rac1 activity during cell migration.

Q96GD4	AURKB_HUMAN	Serine/threonine-protein kinase 12	15064709	Aurora B -TACC1 protein complex in cytokinesis.

P46782	RS5_HUMAN	40S ribosomal protein S5	7772601	Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs.

Q7ZXZ0	MCM3Z_XENLA	Zygotic DNA replication licensing factor mcm3	9512418	Developmental regulation of MCM replication factors in Xenopus laevis.

Q04753	ICLN_RAT	Methylosome subunit pICln	8313467	Molecular characterization of a swelling-induced chloride conductance regulatory protein, pICln.

Q91XL2	LNX2_MOUSE	Ligand of Numb protein X 2	11922143	The Lnx family proteins function as molecular scaffolds for Numb family proteins.

P36631	STE11_SCHPO	Transcription factor ste11	1657709	Schizosaccharomyces pombe ste11+ encodes a transcription factor with an HMG motif that is a critical regulator of sexual development.

Q18685	UN112_CAEEL	Protein unc-112	12015115	C. elegans PAT-4/ILK functions as an adaptor protein within integrin adhesion complexes.

Q9C5X8	MOCOS_ARATH	Molybdenum cofactor sulfurase	11549764	The arabidopsis los5/aba3 locus encodes a molybdenum cofactor sulfurase and modulates cold stress- and osmotic stress-responsive gene expression.

P50264	FMS1_YEAST	Polyamine oxidase FMS1	12670477	Yeast Fms1 is a FAD-utilizing polyamine oxidase.

O00567	NOP56_HUMAN	Nucleolar protein 56	9372940	Nucleolar KKE/D repeat proteins Nop56p and Nop58p interact with Nop1p and are required for ribosome biogenesis.

Q7SIG4	DFPA_LOLVU	Diisopropyl-fluorophosphatase	11134940	Crystallization and preliminary X-ray crystallographic analysis of DFPase from Loligo vulgaris.

Q9I7U4	TITIN_DROME	Titin	10934048	Drosophila D-titin is required for myoblast fusion and skeletal muscle striation.

Q86U42	PABP2_HUMAN	Polyadenylate-binding protein 2	9462747	Short GCG expansions in the PABP2 gene cause oculopharyngeal muscular dystrophy.

O42601	S17B1_XENLA	Transcription factor Sox-17-beta.1	12591603	Redundant early and overlapping larval roles of Xsox17 subgroup genes in Xenopus endoderm development.

O43320	FGF16_HUMAN	Fibroblast growth factor 16	9473496	Structure and expression of a novel member, FGF-16, on the fibroblast growth factor family.

O31666	MTNW_BACSU	2,3-diketo-5-methylthiopentyl-1-phosphate enolase	14551435	A functional link between RuBisCO-like protein of Bacillus and photosynthetic RuBisCO.

Q920L5	ELOV6_MOUSE	Elongation of very long chain fatty acids protein 6	11567032	Identification of a mammalian long chain fatty acyl elongase regulated by sterol regulatory element-binding proteins.

P0ABS5	PRIM_ECOLI	DNA primase	1511009	Enriched sources of Escherichia coli replication proteins. The dnaG primase is a zinc metalloprotein.

P13726	TF_HUMAN	Tissue factor	3037536	Isolation of cDNA clones coding for human tissue factor: primary structure of the protein and cDNA.

Q9P7R3	MTR3_SCHPO	Exosome complex component mtr3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P51812	KS6A3_HUMAN	Ribosomal protein S6 kinase alpha-3	8141249	Human rsk isoforms: cloning and characterization of tissue-specific expression.

Q09902	MU144_SCHPO	Meiotically up-regulated gene 144 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9P371	SST2_SCHPO	AMSH-like protease sst2	17660439	Essential roles of class E Vps proteins for sorting into multivesicular bodies in Schizosaccharomyces pombe.

Q42525	HXK1_ARATH	Hexokinase-1	17081979	Regulatory functions of nuclear hexokinase1 complex in glucose signaling.

Q04739	GAL83_YEAST	SNF1 protein kinase subunit beta-3	7813428	A family of proteins containing a conserved domain that mediates interaction with the yeast SNF1 protein kinase complex.

Q05123	ARP9_YEAST	Actin-like protein ARP9	10025404	Histone octamer transfer by a chromatin-remodeling complex.

P46984	GON7_YEAST	Protein GON7	16874308	Yeast homolog of a cancer-testis antigen defines a new transcription complex.

Q5S007	LRRK2_HUMAN	Leucine-rich repeat serine/threonine-protein kinase 2	16321986	The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity.

P57796	CABP4_HUMAN	Calcium-binding protein 4	10625670	Five members of a novel Ca(2+)-binding protein (CABP) subfamily with similarity to calmodulin.

Q9Z1T4	CNKR2_RAT	Connector enhancer of kinase suppressor of ras 2	10207009	MAGUIN, a novel neuronal membrane-associated guanylate kinase- interacting protein.

Q8T9S7	PTEN_DICDI	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	19011688	Ordered patterns of cell shape and orientational correlation during spontaneous cell migration.

Q03720	SLO_DROME	Calcium-activated potassium channel slowpoke	9539129	Slob, a novel protein that interacts with the Slowpoke calcium- dependent potassium channel.

O94663	SNF8_SCHPO	Vacuolar-sorting protein dot2	15992541	The fission yeast homolog of the human transcription factor EAP30 blocks meiotic spindle pole body amplification.

Q20411	SRA11_CAEEL	Serpentine receptor class alpha-11	16051801	An interneuronal chemoreceptor required for olfactory imprinting in C. elegans.

P0AGK1	UBIA_ECOLI	4-hydroxybenzoate octaprenyltransferase	8155731	Characterization of polyprenyldiphosphate:4-hydroxybenzoate polyprenyltransferase from Escherichia coli.

P38938	CEK1_SCHPO	Serine/threonine-protein kinase cek1	8065367	Identification of cut8+ and cek1+, a novel protein kinase gene, which complement a fission yeast mutation that blocks anaphase.

P32565	RPN2_YEAST	26S proteasome regulatory subunit RPN2	7565784	The yeast SEN3 gene encodes a regulatory subunit of the 26S proteasome complex required for ubiquitin-dependent protein degradation in vivo.

Q99707	METH_HUMAN	Methionine synthase	8968737	Human methionine synthase: cDNA cloning and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders.

Q9FZ36	M3K2_ARATH	Mitogen-activated protein kinase kinase kinase 2	20215588	Arabidopsis homologs of nucleus- and phragmoplast-localized kinase 2 and 3 and mitogen-activated protein kinase 4 are essential for microtubule organization.

P53313	SDA1_YEAST	Protein SDA1	11160833	The Sda1 protein is required for passage through start.

P70175	DLG3_MOUSE	Disks large homolog 3	19243221	Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning.

O14777	NDC80_HUMAN	Kinetochore protein NDC80 homolog	15713649	The functional region of CENP-H interacts with the Nuf2 complex that localizes to centromere during mitosis.

Q03761	TAF12_YEAST	Transcription initiation factor TFIID subunit 12	10788514	Identification of two novel TAF subunits of the yeast Saccharomyces cerevisiae TFIID complex.

Q92826	HXB13_HUMAN	Homeobox protein Hox-B13	9665387	Modulation of the human homeobox genes PRX-2 and HOXB13 in scarless fetal wounds.

Q03497	STE20_YEAST	Serine/threonine-protein kinase STE20	7608157	Molecular characterization of Ste20p, a potential mitogen-activated protein or extracellular signal-regulated kinase kinase (MEK) kinase kinase from Saccharomyces cerevisiae.

O60291	MGRN1_HUMAN	E3 ubiquitin-protein ligase MGRN1	19737927	Mahogunin ring finger-1 (MGRN1) E3 ubiquitin ligase inhibits signaling from melanocortin receptor by competition with Galphas.

Q03933	HSF2_HUMAN	Heat shock factor protein 2	1871106	Isolation of a cDNA for HSF2: evidence for two heat shock factor genes in humans.

Q9UEF7	KLOT_HUMAN	Klotho	9363890	Mutation of the mouse klotho gene leads to a syndrome resembling ageing.

O33244	PSA_MYCTU	Proteasome subunit alpha	18059281	In vivo gene silencing identifies the Mycobacterium tuberculosis proteasome as essential for the bacteria to persist in mice.

Q08603	PGTB2_RAT	Geranylgeranyl transferase type-2 subunit beta	8505342	cDNA cloning and expression of the alpha and beta subunits of rat Rab geranylgeranyl transferase.

Q8BGI3	INSI1_MOUSE	Insulin-induced gene 1 protein	12242332	Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins.

P18654	KS6A3_MOUSE	Ribosomal protein S6 kinase alpha-3	12016217	Characterization of the p90 ribosomal S6 kinase 2 carboxyl-terminal domain as a protein kinase.

P42196	BACS2_NATPH	Sensory rhodopsin-2	12368857	Molecular basis of transmembrane signalling by sensory rhodopsin II- transducer complex.

Q54UH8	SERA_DICDI	D-3-phosphoglycerate dehydrogenase	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q13507	TRPC3_HUMAN	Short transient receptor potential channel 3	10611319	Modulation of Ca(2+) entry by polypeptides of the inositol 1,4, 5- trisphosphate receptor (IP3R) that bind transient receptor potential (TRP): evidence for roles of TRP and IP3R in store depletion-activated Ca(2+) entry.

Q9SU25	T2FA_ARATH	Transcription initiation factor IIF subunit alpha	16905668	Arabidopsis carboxyl-terminal domain phosphatase-like isoforms share common catalytic and interaction domains but have distinct in planta functions.

P62847	RS24_HUMAN	40S ribosomal protein S24	17186470	Ribosomal protein S24 gene is mutated in Diamond-Blackfan anemia.

Q99575	POP1_HUMAN	Ribonucleases P/MRP protein subunit POP1	8918471	hPop1: an autoantigenic protein subunit shared by the human RNase P and RNase MRP ribonucleoproteins.

O54864	SUV91_MOUSE	Histone-lysine N-methyltransferase SUV39H1	18619962	A novel interaction between the proto-oncogene Evi1 and histone methyltransferases, SUV39H1 and G9a.

Q9FJA2	TT2_ARATH	Transcription factor TT2	11549766	The Arabidopsis TT2 gene encodes an R2R3 MYB domain protein that acts as a key determinant for proanthocyanidin accumulation in developing seed.

P18961	YPK2_YEAST	Serine/threonine-protein kinase YPK2/YKR2	12221112	Pkh1 and pkh2 differentially phosphorylate and activate ypk1 and ykr2 and define protein kinase modules required for maintenance of cell wall integrity.

Q08495	DEMA_HUMAN	Dematin	8341682	Cloning of human erythroid dematin reveals another member of the villin family.

P61621	S61A1_RAT	Protein transport protein Sec61 subunit alpha isoform 1	1423609	A mammalian homolog of SEC61p and SECYp is associated with ribosomes and nascent polypeptides during translocation.

O75469	NR1I2_HUMAN	Nuclear receptor subfamily 1 group I member 2	9727070	The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions.

P21524	RIR1_YEAST	Ribonucleoside-diphosphate reductase large chain 1	11893751	Yeast DNA damage-inducible Rnr3 has a very low catalytic activity strongly stimulated after the formation of a cross-talking Rnr1/Rnr3 complex.

P32558	SPT16_YEAST	FACT complex subunit SPT16	11432837	Spt16-Pob3 and the HMG protein Nhp6 combine to form the nucleosome- binding factor SPN.

Q6NQ88	DDB2_ARATH	Protein DAMAGED DNA-BINDING 2	18551167	Regulation and role of Arabidopsis CUL4-DDB1A-DDB2 in maintaining genome integrity upon UV stress.

Q9Y801	YFAS1_SCHPO	FAS1 domain-containing protein mug57	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

Q03195	RLI1_YEAST	Translation initiation factor RLI1	15277527	The essential ATP-binding cassette protein RLI1 functions in translation by promoting preinitiation complex assembly.

Q9SVC6	PUB22_ARATH	E3 ubiquitin-protein ligase PUB22	18664614	Arabidopsis PUB22 and PUB23 are homologous U-Box E3 ubiquitin ligases that play combinatory roles in response to drought stress.

Q12933	TRAF2_HUMAN	TNF receptor-associated factor 2	10892748	A novel mechanism of TRAF signaling revealed by structural and functional analyses of the TRADD-TRAF2 interaction.

O75154	RFIP3_HUMAN	Rab11 family-interacting protein 3	16148947	Rab11-FIP3 and FIP4 interact with Arf6 and the exocyst to control membrane traffic in cytokinesis.

O15143	ARC1B_HUMAN	Actin-related protein 2/3 complex subunit 1B	9230079	The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly.

P42761	GSTF3_ARATH	Glutathione S-transferase ERD13	8253194	Characterization of two cDNAs (ERD11 and ERD13) for dehydration- inducible genes that encode putative glutathione S-transferases in Arabidopsis thaliana L.

P47972	NPTX2_HUMAN	Neuronal pentraxin-2	8530029	Human neuronal pentraxin II (NPTX2): conservation, genomic structure, and chromosomal localization.

Q9WV75	SPON2_RAT	Spondin-2	10409509	F-spondin and mindin: two structurally and functionally related genes expressed in the hippocampus that promote outgrowth of embryonic hippocampal neurons.

P10868	GAMT_RAT	Guanidinoacetate N-methyltransferase	12079381	Crystal structure of guanidinoacetate methyltransferase from rat liver: a model structure of protein arginine methyltransferase.

P70056	FOXH1_XENLA	Forkhead box protein H1	11937490	The role of a Williams-Beuren syndrome-associated helix-loop-helix domain-containing transcription factor in activin/nodal signaling.

O93507	TAL1_DANRE	T-cell acute lymphocytic leukemia protein 1 homolog	15644413	Scl is required for dorsal aorta as well as blood formation in zebrafish embryos.

P20851	C4BPB_HUMAN	C4b-binding protein beta chain	8325877	The human C4b-binding protein beta-chain gene.

Q9UTM1	YIV1_SCHPO	Uncharacterized protein C144.01	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q13111	CAF1A_HUMAN	Chromatin assembly factor 1 subunit A	15882967	The mammalian heterochromatin protein 1 binds diverse nuclear proteins through a common motif that targets the chromoshadow domain.

Q9P7E0	QCR10_SCHPO	Cytochrome b-c1 complex subunit 10	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UKA8	RCAN3_HUMAN	Calcipressin-3	10756093	A new gene family including DSCR1 (Down syndrome candidate region 1) and ZAKI-4: characterization from yeast to human and identification of DSCR1-like 2, a novel human member (DSCR1L2).

P10600	TGFB3_HUMAN	Transforming growth factor beta-3	17827158	Mechanisms for asporin function and regulation in articular cartilage.

P45425	NANK_ECOLI	N-acetylmannosamine kinase	15157072	Identifying latent enzyme activities: substrate ambiguity within modern bacterial sugar kinases.

P54274	TERF1_HUMAN	Telomeric repeat-binding factor 1	15383534	Telosome, a mammalian telomere-associated complex formed by multiple telomeric proteins.

Q9JLF6	TGM1_MOUSE	Protein-glutamine gamma-glutamyltransferase K	10567386	Transglutaminase type 1 and its cross-linking activity are concentrated at adherens junctions in simple epithelial cells.

P38167	ECM21_YEAST	Protein ECM21	14562095	Global analysis of protein localization in budding yeast.

P97378	I12R2_MOUSE	Interleukin-12 receptor subunit beta-2	11489994	A point mutation in the IL-12R beta 2 gene underlies the IL-12 unresponsiveness of Lps-defective C57BL/10ScCr mice.

Q54WR4	PLDB_DICDI	Phospholipase D B	15821129	PldB, a putative phospholipase D homologue in Dictyostelium discoideum mediates quorum sensing during development.

P06400	RB_HUMAN	Retinoblastoma-associated protein	9858607	Rb inhibits the intrinsic kinase activity of TATA-binding protein- associated factor TAFII250.

Q9R1N9	CODA1_MOUSE	Collagen alpha-1(XIII) chain	11470398	Distinct expression of type XIII collagen in neuronal structures and other tissues during mouse development.

P39103	COX14_YEAST	Cytochrome c oxidase assembly protein COX14	7797555	Cloning and characterization of COX14, whose product is required for assembly of yeast cytochrome oxidase.

Q39233	SYP21_ARATH	Syntaxin-21	9144962	The syntaxin homolog AtPEP12p resides on a late post-Golgi compartment in plants.

P10155	RO60_HUMAN	60 kDa SS-A/Ro ribonucleoprotein	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

O15394	NCAM2_HUMAN	Neural cell adhesion molecule 2	9226371	Cloning of a novel human neural cell adhesion molecule gene (NCAM2) that maps to chromosome region 21q21 and is potentially involved in Down syndrome.

Q8VHV1	BAALC_MOUSE	Brain and acute leukemia cytoplasmic protein	15749074	Baalc, a marker of mesoderm and muscle.

P08138	TNR16_HUMAN	Tumor necrosis factor receptor superfamily member 16	9915784	Association of the p75 neurotrophin receptor with TRAF6.

Q08388	PEMT_RAT	Phosphatidylethanolamine N-methyltransferase	8344945	Cloning and expression of a novel phosphatidylethanolamine N- methyltransferase. A specific biochemical and cytological marker for a unique membrane fraction in rat liver.

P93025	PHOT2_ARATH	Phototropin-2	11371609	Arabidopsis nph1 and npl1: blue light receptors that mediate both phototropism and chloroplast relocation.

Q13322	GRB10_HUMAN	Growth factor receptor-bound protein 10	9006901	Human GRB-IR-beta/GRB10: splice variants of an insulin and growth factor receptor-binding protein with PH and SH2 domains.

P40976	LYS2_SCHPO	L-aminoadipate-semialdehyde dehydrogenase	15546125	Posttranslational activation, site-directed mutation and phylogenetic analyses of the lysine biosynthesis enzymes alpha-aminoadipate reductase Lys1p (AAR) and the phosphopantetheinyl transferase Lys7p (PPTase) from Schizosaccharomyces pombe.

Q17802	CPG1_CAEEL	Chondroitin proteoglycan 1	11562350	Identification of in vivo mRNA targets of GLD-1, a maxi-KH motif containing protein required for C. elegans germ cell development.

Q08229	NBA1_YEAST	Protein NBA1	14562095	Global analysis of protein localization in budding yeast.

P39102	XDJ1_YEAST	DnaJ protein homolog XDJ1	14562095	Global analysis of protein localization in budding yeast.

P21825	SEC62_YEAST	Translocation protein SEC62	7758110	Posttranslational protein transport in yeast reconstituted with a purified complex of Sec proteins and Kar2p.

P12821	ACE_HUMAN	Angiotensin-converting enzyme	16116425	Mutations in genes in the renin-angiotensin system are associated with autosomal recessive renal tubular dysgenesis.

Q09196	MLR4_SCHPO	Myosin regulatory light chain cdc4	11087749	Cdc4p, a contractile ring protein essential for cytokinesis in Schizosaccharomyces pombe, interacts with a phosphatidylinositol 4- kinase.

P83949	UBX_DROME	Homeotic protein ultrabithorax	1673656	Optimal DNA sequence recognition by the Ultrabithorax homeodomain of Drosophila.

P43682	SFT1_YEAST	Protein transport protein SFT1	7596416	A SNARE-like protein required for traffic through the Golgi complex.

O76027	ANXA9_HUMAN	Annexin A9	10899159	Pemphigus vulgaris antibody identifies pemphaxin. A novel keratinocyte annexin-like molecule binding acetylcholine.

P12939	CP2DA_RAT	Cytochrome P450 2D10	2107330	The rat P450 IID subfamily: complete sequences of four closely linked genes and evidence that gene conversions maintained sequence homogeneity at the heme-binding region of the cytochrome P450 active site.

P56402	AQP2_MOUSE	Aquaporin-2	10191086	cDNA and genomic cloning of mouse aquaporin-2: functional analysis of an orthologous mutant causing nephrogenic diabetes insipidus.

P51579	P2RX6_RAT	P2X purinoceptor 6	8786426	Cloning of P2X5 and P2X6 receptors and the distribution and properties of an extended family of ATP-gated ion channels.

O15403	MOT7_HUMAN	Monocarboxylate transporter 7	9425115	Cloning and sequencing of four new mammalian monocarboxylate transporter (MCT) homologues confirms the existence of a transporter family with an ancient past.

P78347	GTF2I_HUMAN	General transcription factor II-I	9012831	BAP-135, a target for Bruton's tyrosine kinase in response to B cell receptor engagement.

Q6UWH4	F198B_HUMAN	Protein FAM198B	11256614	Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.

Q7XIM7	YAB1_ORYSJ	Protein YABBY 1	15604733	Ectopic expression of OsYAB1 causes extra stamens and carpels in rice.

P00787	CATB_RAT	Cathepsin B	2986112	Identification of cDNA clones encoding a precursor of rat liver cathepsin B.

Q03940	RUVB1_YEAST	RuvB-like protein 1	12576485	Impairment of the DNA binding activity of the TATA-binding protein renders the transcriptional function of Rvb2p/Tih2p, the yeast RuvB- like protein, essential for cell growth.

P08185	CBG_HUMAN	Corticosteroid-binding globulin	3299377	Primary structure of human corticosteroid binding globulin, deduced from hepatic and pulmonary cDNAs, exhibits homology with serine protease inhibitors.

Q9NP97	DLRB1_HUMAN	Dynein light chain roadblock-type 1	11750132	Identification of two novel human dynein light chain genes, DNLC2A and DNLC2B, and their expression changes in hepatocellular carcinoma tissues from 68 Chinese patients.

Q07623	NOP6_YEAST	Nucleolar protein 6	14562095	Global analysis of protein localization in budding yeast.

P25932	ESCA_DROME	Protein escargot	8620833	Determination of wing cell fate by the escargot and snail genes in Drosophila.

Q10430	SPC25_SCHPO	Kinetochore protein spc25	16079914	Molecular analysis of kinetochore architecture in fission yeast.

Q6GYQ0	RGPA1_HUMAN	Ral GTPase-activating protein subunit alpha-1	19520869	Tuberous sclerosis tumor suppressor complex-like complexes act as GTPase-activating proteins for Ral GTPases.

Q9M077	AUR1_ARATH	Serine/threonine-protein kinase Aurora-1	15722465	Identification and dynamics of two classes of aurora-like kinases in Arabidopsis and other plants.

Q96PE2	ARHGH_HUMAN	Rho guanine nucleotide exchange factor 17	12071859	A mammalian Rho-specific guanine-nucleotide exchange factor (p164- RhoGEF) without a pleckstrin homology domain.

Q66K74	MAP1S_HUMAN	Microtubule-associated protein 1S	12762840	Novel complex integrating mitochondria and the microtubular cytoskeleton with chromosome remodeling and tumor suppressor RASSF1 deduced by in silico homology analysis, interaction cloning in yeast, and colocalization in cultured cells.

P08568	GRPA_RAT	Submandibular gland secretory Glx-rich protein CA	2438276	Molecular characterization of glutamic acid/glutamine-rich secretory proteins from rat submandibular glands.

Q9UNN4	TF2AY_HUMAN	TFIIA-alpha and beta-like factor	10364255	Identification of a general transcription factor TFIIAalpha/beta homolog selectively expressed in testis.

Q92793	CBP_HUMAN	CREB-binding protein	15488321	The calcium-responsive transactivator recruits CREB binding protein to nuclear bodies.

P38927	REV7_YEAST	DNA polymerase zeta processivity subunit	16452144	Saccharomyces cerevisiae polymerase zeta functions in mitochondria.

P56182	RRP1_HUMAN	Ribosomal RNA processing protein 1 homolog A	9192856	The NNP-1 gene (D21S2056E), which encodes a novel nuclear protein, maps in close proximity to the cystatin B gene within the EPM1 and APECED critical region on 21q22.3.

O01700	DLK1_CAEEL	Mitogen-activated protein kinase kinase kinase dlk-1	15707898	Regulation of a DLK-1 and p38 MAP kinase pathway by the ubiquitin ligase RPM-1 is required for presynaptic development.

P49336	CDK8_HUMAN	Cell division protein kinase 8	7568034	Identification of human cyclin-dependent kinase 8, a putative protein kinase partner for cyclin C.

P0A6S5	FTSB_ECOLI	Cell division protein ftsB	11972052	YgbQ, a cell division protein in Escherichia coli and Vibrio cholerae, localizes in codependent fashion with FtsL to the division site.

Q12036	PPT2_YEAST	Mitochondrial holo-[acyl-carrier-protein] synthase	9712852	A novel phosphopantetheine:protein transferase activating yeast mitochondrial acyl carrier protein.

Q02354	UTP6_YEAST	U3 small nucleolar RNA-associated protein 6	12068309	A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis.

Q9HCL2	GPAT1_HUMAN	Glycerol-3-phosphate acyltransferase 1, mitochondrial	18238778	AGPAT6 is a novel microsomal glycerol-3-phosphate acyltransferase.

O08915	AIP_MOUSE	AH receptor-interacting protein	9083006	A novel cytoplasmic protein that interacts with the Ah receptor, contains tetratricopeptide repeat motifs, and augments the transcriptional response to 2,3,7,8-tetrachlorodibenzo-p-dioxin.

A8JUV0	SBNO_DROME	Protein strawberry notch	9171377	strawberry notch encodes a conserved nuclear protein that functions downstream of Notch and regulates gene expression along the developing wing margin of Drosophila.

Q9SB60	IPT4_ARATH	Adenylate isopentenyltransferase 4	17062755	Roles of Arabidopsis ATP/ADP isopentenyltransferases and tRNA isopentenyltransferases in cytokinin biosynthesis.

Q93352	HM36_CAEEL	Homeobox protein ceh-36	14536063	Otx/otd homeobox genes specify distinct sensory neuron identities in C. elegans.

Q12204	YOR22_YEAST	Probable phospholipase YOR022C, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

P37818	ARGI1_SCHPO	Arginase	7985419	Cloning and sequencing of Schizosaccharomyces pombe car1 gene encoding arginase. Expression of the arginine anabolic and catabolic genes in response to arginine and related metabolites.

P06737	PYGL_HUMAN	Glycogen phosphorylase, liver form	9529348	Mutations in the liver glycogen phosphorylase gene 'PYGL' underlying glycogenosis type VI.

Q16517	NNAT_HUMAN	Neuronatin	8813377	Cloning of human neuronatin gene and its localization to chromosome- 20q 11.2-12: the deduced protein is a novel 'proteolipid'.

P40533	TED1_YEAST	Protein TED1	14562095	Global analysis of protein localization in budding yeast.

P24033	CDK1B_XENLA	Cell division protein kinase 1-B	10465793	A novel p34cdc2 binding and activating protein that is necessary and sufficient to trigger G2/M progression in Xenopus oocytes.

P31271	HXA13_HUMAN	Homeobox protein Hox-A13	9020844	Mutation of HOXA13 in hand-foot-genital syndrome.

P35240	MERL_HUMAN	Merlin	8379998	Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2.

Q9EST6	AN32B_RAT	Acidic leucine-rich nuclear phosphoprotein 32 family member B	11162633	PAL31, a nuclear protein required for progression to the S phase.

P84003	HYB2_HYLBI	Hylin-b2	15638808	Hylins: bombinins H structurally related peptides from the skin secretion of the Brazilian tree-frog Hyla biobeba.

P54939	TLN1_CHICK	Talin-1	9786953	Layilin, a novel talin-binding transmembrane protein homologous with C-type lectins, is localized in membrane ruffles.

P63211	GBG1_HUMAN	Guanine nucleotide-binding protein G(T) subunit gamma-T1	8661128	Gene structure and chromosome localization to 7q21.3 of the human rod photoreceptor transducin gamma-subunit gene (GNGT1).

Q7K4N3	NCBP1_DROME	Nuclear cap-binding protein subunit 1	19632183	Ars2 regulates both miRNA- and siRNA- dependent silencing and suppresses RNA virus infection in Drosophila.

P38649	BGAT_MOUSE	Histo-blood group ABO system transferase	11278752	Murine equivalent of the human histo-blood group ABO gene is a cis-AB gene and encodes a glycosyltransferase with both A and B transferase activity.

O54967	ACK1_MOUSE	Activated CDC42 kinase 1	16052498	Expression, synaptic localization, and developmental regulation of Ack1/Pyk1, a cytoplasmic tyrosine kinase highly expressed in the developing and adult brain.

Q8LBL1	KCO1_ARATH	Calcium-activated outward-rectifying potassium channel 1	11821043	KCO1 is a component of the slow-vacuolar (SV) ion channel.

Q61092	LAMC2_MOUSE	Laminin subunit gamma-2	11733994	Short arm region of laminin-5 gamma2 chain: structure, mechanism of processing and binding to heparin and proteins.

P43609	RSC8_YEAST	Chromatin structure-remodeling complex protein RSC8	9121424	Interaction of a Swi3 homolog with Sth1 provides evidence for a Swi/Snf-related complex with an essential function in Saccharomyces cerevisiae.

Q9NVP1	DDX18_HUMAN	ATP-dependent RNA helicase DDX18	8861962	Myc-Max heterodimers activate a DEAD box gene and interact with multiple E box-related sites in vivo.

Q5EBH1	RASF5_MOUSE	Ras association domain-containing protein 5	11857081	The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore1.

Q9NSD7	RL3R1_HUMAN	Relaxin-3 receptor 1	14522968	Identification of relaxin-3/INSL7 as an endogenous ligand for the orphan G-protein coupled receptor GPCR135.

Q5U5Q9	UIMC1_MOUSE	BRCA1-A complex subunit RAP80	7760852	Isolation of proteins that interact specifically with the retinoid X receptor: two novel orphan receptors.

Q61496	DDX4_MOUSE	Probable ATP-dependent RNA helicase DDX4	14736746	Mili, a mammalian member of piwi family gene, is essential for spermatogenesis.

Q99M66	B2L10_RAT	Bcl-2-like protein 10	12787069	Bcl-2-related protein family gene expression during oligodendroglial differentiation.

P22213	SLY1_YEAST	Protein SLY1	1990290	Identification and structure of four yeast genes (SLY) that are able to suppress the functional loss of YPT1, a member of the RAS superfamily.

Q9VSH2	GR66A_DROME	Putative gustatory receptor 66a	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

P43287	PIP22_ARATH	Aquaporin PIP2-2	7920711	Water channels in the plant plasma membrane cloned by immunoselection from a mammalian expression system.

Q9Y6F8	CDY1_HUMAN	Testis-specific chromodomain protein Y 1	9381176	Functional coherence of the human Y chromosome.

Q9NZC7	WWOX_HUMAN	WW domain-containing oxidoreductase	10861292	Common chromosomal fragile site FRA16D sequence: identification of the FOR gene spanning FRA16D and homozygous deletions and translocation breakpoints in cancer cells.

Q9NYW2	TA2R8_HUMAN	Taste receptor type 2 member 8	10761934	A novel family of mammalian taste receptors.

Q9QX82	MUC24_RAT	Sialomucin core protein 24	10620506	Endolyn is a mucin-like type I membrane protein targeted to lysosomes by its cytoplasmic tail.

O14194	GGT2_SCHPO	Gamma-glutamyltranspeptidase 2	16202243	The gene encoding gamma-glutamyl transpeptidase II in the fission yeast is regulated by oxidative and metabolic stress.

Q61495	DSG1A_MOUSE	Desmoglein-1-alpha	12631242	Novel member of the mouse desmoglein gene family: Dsg1-beta.

P54793	ARSF_HUMAN	Arylsulfatase F	9192838	Identification by shotgun sequencing, genomic organization, and functional analysis of a fourth arylsulfatase gene (ARSF) from the Xp22.3 region.

O15488	GLYG2_HUMAN	Glycogenin-2	9346895	Glycogenin-2, a novel self-glucosylating protein involved in liver glycogen biosynthesis.

Q9UKU9	ANGL2_HUMAN	Angiopoietin-related protein 2	10473614	Molecular cloning, expression, and characterization of angiopoietin- related protein. angiopoietin-related protein induces endothelial cell sprouting.

Q6VH22	IF172_MOUSE	Intraflagellar transport protein 172 homolog	11062270	Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella.

Q12030	TAF10_YEAST	Transcription initiation factor TFIID subunit 10	9674426	A subset of TAF(II)s are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulation.

P23503	NAR1_YEAST	Cytosolic Fe-S cluster assembly factor NAR1	19385603	Crucial role of conserved cysteine residues in the assembly of two iron-sulfur clusters on the CIA protein Nar1.

O13024	INCEA_XENLA	Inner centromere protein A	12221116	Aurora B kinase exists in a complex with survivin and INCENP and its kinase activity is stimulated by survivin binding and phosphorylation.

O43255	SIAH2_HUMAN	E3 ubiquitin-protein ligase SIAH2	10207103	hSiah2 is a new Vav binding protein which inhibits Vav-mediated signaling pathways.

P39985	DPO5_YEAST	DNA polymerase V	12093911	The fifth essential DNA polymerase phi in Saccharomyces cerevisiae is localized to the nucleolus and plays an important role in synthesis of rRNA.

Q9Y5A9	YTHD2_HUMAN	YTH domain family protein 2	10508479	Antigens recognized by autologous antibody in patients with renal- cell carcinoma.

P61765	STXB1_RAT	Syntaxin-binding protein 1	10746715	Three-dimensional structure of the neuronal-Sec1-syntaxin 1a complex.

P12843	IBP2_RAT	Insulin-like growth factor-binding protein 2	2480123	Identification of a novel binding protein for insulin-like growth factors in adult rat serum.

O60291	MGRN1_HUMAN	E3 ubiquitin-protein ligase MGRN1	17229889	Spongiform neurodegeneration-associated E3 ligase Mahogunin ubiquitylates TSG101 and regulates endosomal trafficking.

P84809	LVP1B_BUTOC	Lipolysis-activating peptide 1-beta chain	15680238	Isolation and molecular characterization of LVP1 lipolysis activating peptide from scorpion Buthus occitanus tunetanus.

P87060	POP1_SCHPO	WD repeat-containing protein pop1	15147268	Molecular interactions of fission yeast Skp1 and its role in the DNA damage checkpoint.

Q8L7E5	WIT1_ARATH	WPP domain-interacting tail-anchored protein 1	18591351	Two distinct interacting classes of nuclear envelope-associated coiled-coil proteins are required for the tissue-specific nuclear envelope targeting of Arabidopsis RanGAP.

P87052	MUG10_SCHPO	Meiotically up-regulated gene 10 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P32529	RPA12_YEAST	DNA-directed RNA polymerase I subunit RPA12	15073335	Transcriptional termination by RNA polymerase I requires the small subunit Rpa12p.

Q63942	RAB3D_RAT	GTP-binding protein Rab-3D	7532276	Interaction cloning of Rabin3, a novel protein that associates with the Ras-like GTPase Rab3A.

P53620	COPG_BOVIN	Coatomer subunit gamma	8700856	Nonclathrin coat protein gamma, a subunit of coatomer, binds to the cytoplasmic dilysine motif of membrane proteins of the early secretory pathway.

Q9LLC6	PETO_CHLRE	Cytochrome b6-f complex subunit petO, chloroplastic	10748028	A new subunit of cytochrome b6f complex undergoes reversible phosphorylation upon state transition.

P54730	UBX4_YEAST	UBX domain-containing protein 4	15258615	Shp1 and Ubx2 are adaptors of Cdc48 involved in ubiquitin-dependent protein degradation.

Q80W92	VAC14_RAT	Protein VAC14 homolog	12719380	Congenital hydrocephalus in hy3 mice is caused by a frameshift mutation in Hydin, a large novel gene.

Q16602	CALRL_HUMAN	Calcitonin gene-related peptide type 1 receptor	7818539	A human orphan calcitonin receptor-like structure.

P62877	RBX1_HUMAN	E3 ubiquitin-protein ligase RBX1	12732143	The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage.

Q9P6N1	ATG21_SCHPO	Autophagy-related protein 21	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P35670	ATP7B_HUMAN	Copper-transporting ATPase 2	8298641	The Wilson disease gene is a copper transporting ATPase with homology to the Menkes disease gene.

Q9EQ76	FMO3_RAT	Dimethylaniline monooxygenase [N-oxide-forming] 3	11414682	Cloning, sequencing, tissue distribution, and heterologous expression of rat flavin-containing monooxygenase 3.

Q99801	NKX31_HUMAN	Homeobox protein Nkx-3.1	18077445	Ubiquitination by TOPORS regulates the prostate tumor suppressor NKX3.1.

P41797	HSP71_CANAL	Heat shock protein SSA1	7558317	Molecular cloning and expression of a 70-kilodalton heat shock protein of Candida albicans.

P31652	SC6A4_RAT	Sodium-dependent serotonin transporter	15627510	Role of C-terminal region in the functional regulation of rat serotonin transporter (SERT).

P53759	DUS1_YEAST	tRNA-dihydrouridine synthase 1	14970222	The specificities of four yeast dihydrouridine synthases for cytoplasmic tRNAs.

Q9BX26	SYCP2_HUMAN	Synaptonemal complex protein 2	10341103	Isolation and characterization of the human SCP2 cDNA and chromosomal localization of the gene.

Q9FNQ2	E13L2_ARATH	Glucan endo-1,3-beta-glucosidase-like protein 2	14517339	Proteomic analysis of glycosylphosphatidylinositol-anchored membrane proteins.

P36188	TNNI_DROME	Troponin I	1899228	Troponin I is encoded in the haplolethal region of the Shaker gene complex of Drosophila.

Q99504	EYA3_HUMAN	Eyes absent homolog 3	19234442	Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions.

Q9C826	ABA2_ARATH	Xanthoxin dehydrogenase	12172025	The short-chain alcohol dehydrogenase ABA2 catalyzes the conversion of xanthoxin to abscisic aldehyde.

Q07821	ISA1_YEAST	Iron-sulfur assembly protein 1	10748136	Isa1p is a component of the mitochondrial machinery for maturation of cellular iron-sulfur proteins and requires conserved cysteine residues for function.

O42569	SOX2_XENLA	Transcription factor Sox-2	9435279	Xenopus Zic-related-1 and Sox-2, two factors induced by chordin, have distinct activities in the initiation of neural induction.

Q8R4Z4	ETV3_MOUSE	ETS translocation variant 3	12007404	An induced Ets repressor complex regulates growth arrest during terminal macrophage differentiation.

P28221	5HT1D_HUMAN	5-hydroxytryptamine receptor 1D	1652050	Primary structure and functional characterization of a human 5-HT1D- type serotonin receptor.

Q9HB90	RRAGC_HUMAN	Ras-related GTP-binding protein C	11073942	Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B.

Q8CGA3	LAT4_MOUSE	Large neutral amino acids transporter small subunit 4	15659399	Identification of LAT4, a novel amino acid transporter with system L activity.

P41917	RAN2_ARATH	GTP-binding nuclear protein Ran-2	9025305	Characterization of proteins that interact with the GTP-bound form of the regulatory GTPase Ran in Arabidopsis.

Q9Y6K9	NEMO_HUMAN	NF-kappa-B essential modulator	15125833	The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes.

Q9USW2	YHZ6_SCHPO	Uncharacterized membrane protein C21B10.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q03111	ENL_HUMAN	Protein ENL	8080983	ENL, the gene fused with HRX in t(11;19) leukemias, encodes a nuclear protein with transcriptional activation potential in lymphoid and myeloid cells.

Q1JPY4	TBPL2_DANRE	TATA box-binding protein-like protein 2	18046332	Initiation of zebrafish haematopoiesis by the TATA-box-binding protein-related factor Trf3.

P30628	VPP1_CAEEL	Probable V-type proton ATPase 116 kDa subunit a	11110798	The Caenorhabditis elegans unc-32 gene encodes alternative forms of a vacuolar ATPase a subunit.

Q9UT91	RMP1_SCHPO	Ribonuclease MRP protein subunit rmp1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q17353	PAR3_CAEEL	Partitioning defective protein 3	9716526	Atypical protein kinase C cooperates with PAR-3 to establish embryonic polarity in Caenorhabditis elegans.

P15257	HNF1A_RAT	Hepatocyte nuclear factor 1-alpha	7937157	LFB1/HNF1 acts as a repressor of its own transcription.

P32578	SIP1_YEAST	SNF1 protein kinase subunit beta-1	10990457	beta-subunits of Snf1 kinase are required for kinase function and substrate definition.

O14531	DPYL4_HUMAN	Dihydropyrimidinase-related protein 4	9652388	The Ulip family phosphoproteins -- common and specific properties.

Q9NV58	RN19A_HUMAN	E3 ubiquitin-protein ligase RNF19A	11237715	A novel centrosomal ring-finger protein, dorfin, mediates ubiquitin ligase activity.

P18074	ERCC2_HUMAN	TFIIH basal transcription factor complex helicase XPD subunit	9852112	Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.

Q8IYM1	SEP12_HUMAN	Septin-12	18443421	GTP binding is required for SEPT12 to form filaments and to interact with SEPT11.

Q6WAY2	LPPR1_RAT	Lipid phosphate phosphatase-related protein type 1	14750979	Molecular cloning and expression regulation of PRG-3, a new member of the plasticity-related gene family.

P50457	PUUE_ECOLI	4-aminobutyrate aminotransferase	15590624	A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.

P55735	SEC13_HUMAN	Protein SEC13 homolog	7987303	Molecular characterization of a novel human gene, SEC13R, related to the yeast secretory pathway gene SEC13, and mapping to a conserved linkage group on human chromosome 3p24-p25 and mouse chromosome 6.

P40505	SDS3_YEAST	Transcriptional regulatory protein SDS3	16286008	Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex.

O14863	ZNT4_HUMAN	Zinc transporter 4	9354792	A novel gene involved in zinc transport is deficient in the lethal milk mouse.

Q9NRD9	DUOX1_HUMAN	Dual oxidase 1	10806195	Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family.

Q92793	CBP_HUMAN	CREB-binding protein	11742995	Activation of AML1-mediated transcription by MOZ and inhibition by the MOZ-CBP fusion protein.

Q9UHC6	CNTP2_HUMAN	Contactin-associated protein-like 2	18179895	Molecular cytogenetic analysis and resequencing of contactin associated protein-like 2 in autism spectrum disorders.

P84022	SMAD3_HUMAN	Mothers against decapentaplegic homolog 3	17292623	Fussel-15, a novel Ski/Sno homolog protein, antagonizes BMP signaling.

P50454	SERPH_HUMAN	Serpin H1	7656593	Isolation, characterization and chromosomal assignment of human colligin-2 gene (CBP2).

P53671	LIMK2_HUMAN	LIM domain kinase 2	8537403	Identification and characterization of a novel family of serine/threonine kinases containing two N-terminal LIM motifs.

Q9W0V1	PDPK1_DROME	3-phosphoinositide-dependent protein kinase 1	9368760	3-phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase.

Q9VJS8	ELBOW_DROME	Zinc finger protein Elbow	17014842	Growth control in the proliferative region of the Drosophila eye-head primordium: the elbow-noc gene complex.

Q5U4X3	MEI3A_XENLA	Homeobox protein meis3-A	11566847	Genetic evidence for the transcriptional-activating function of Homothorax during adult fly development.

Q9Y5Z7	HCFC2_HUMAN	Host cell factor 2	10196288	Herpes simplex virus transactivator VP16 discriminates between HCF-1 and a novel family member, HCF-2.

O96642	TWIST_BRABE	Twist-related protein	9520323	Expression of a twist-related gene, Bbtwist, during the development of a lancelet species and its relation to cephalochordate anterior structures.

P22361	HNF1A_MOUSE	Hepatocyte nuclear factor 1-alpha	9566924	Laron dwarfism and non-insulin-dependent diabetes mellitus in the Hnf-1alpha knockout mouse.

O94321	MPR1_SCHPO	Multistep phosphorelay regulator 1	10749922	Multistep phosphorelay proteins transmit oxidative stress signals to the fission yeast stress-activated protein kinase.

O60282	KIF5C_HUMAN	Kinesin heavy chain isoform 5C	15644324	GRIF-1 and OIP106, members of a novel gene family of coiled-coil domain proteins: association in vivo and in vitro with kinesin.

Q22703	TFDP1_CAEEL	Transcription factor dpl-1	11463372	dpl-1 DP and efl-1 E2F act with lin-35 Rb to antagonize Ras signaling in C.elegans vulval development.

P08779	K1C16_HUMAN	Keratin, type I cytoskeletal 16	2451124	A group of type I keratin genes on human chromosome 17: characterization and expression.

P51843	NR0B1_HUMAN	Nuclear receptor subfamily 0 group B member 1	7990953	An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita.

Q10321	SHG1_SCHPO	Set1 complex component shg1	12488447	High conservation of the Set1/Rad6 axis of histone 3 lysine 4 methylation in budding and fission yeasts.

O75676	KS6A4_HUMAN	Ribosomal protein S6 kinase alpha-4	9792677	RSK-B, a novel ribosomal S6 kinase family member, is a CREB kinase under dominant control of p38alpha mitogen-activated protein kinase (p38alphaMAPK).

P79920	NDF4_XENLA	Neurogenic differentiation factor 4	17008450	Characterization and function of the bHLH-O protein XHes2: insight into the mechanisms controlling retinal cell fate decision.

P38398	BRCA1_HUMAN	Breast cancer type 1 susceptibility protein	12419185	NBS1 localizes to gamma-H2AX foci through interaction with the FHA/BRCT domain.

P60893	GPR85_HUMAN	Probable G-protein coupled receptor 85	10833454	An evolutionarily conserved G-protein coupled receptor family, SREB, expressed in the central nervous system.

Q08179	MDM38_YEAST	Mitochondrial distribution and morphology protein 38	14562095	Global analysis of protein localization in budding yeast.

Q9ULX6	AKP8L_HUMAN	A-kinase anchor protein 8-like	10748171	A novel shuttle protein binds to RNA helicase A and activates the retroviral constitutive transport element.

Q08685	CLP1_YEAST	Protein CLP1	11344258	Five subunits are required for reconstitution of the cleavage and polyadenylation activities of Saccharomyces cerevisiae cleavage factor I.

Q9P546	RSSA2_SCHPO	40S ribosomal protein S0-B	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O43889	CREB3_HUMAN	Cyclic AMP-responsive element-binding protein 3	15001559	Human LZIP binds to CCR1 and differentially affects the chemotactic activities of CCR1-dependent chemokines.

O00391	QSOX1_HUMAN	Sulfhydryl oxidase 1	10708601	Regulation of the quiescence-induced genes: quiescin Q6, decorin, and ribosomal protein S29.

Q92859	NEO1_HUMAN	Neogenin	9169140	Molecular characterization of human neogenin, a DCC-related protein, and the mapping of its gene (NEO1) to chromosomal position 15q22.3- q23.

P01346	IGF2_RAT	Insulin-like growth factor II	6390212	Isolation of a cDNA clone encoding rat insulin-like growth factor-II precursor.

P19334	TRP_DROME	Transient receptor potential protein	2482778	Proper function of the Drosophila trp gene product during pupal development is important for normal visual transduction in the adult.

P01817	HV204_HUMAN	Ig heavy chain V-II region MCE	6780622	Molecular basis for the temperature-dependent insolubility of cryoglobulins. X. The amino acid sequence of the heavy chain variable region of McE.

Q91XD2	LIMS2_MOUSE	LIM and senescent cell antigen-like-containing domain protein 2	12651156	PINCH2 is a new five LIM domain protein, homologous to PINCH and localized to focal adhesions.

Q9FHW7	SKP1B_ARATH	SKP1-like protein 1B	14749489	Expression and interaction analysis of Arabidopsis Skp1-related genes.

P31376	SWC3_YEAST	SWR1-complex protein 3	14690608	A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1.

P32791	FRE1_YEAST	Ferric/cupric reductase transmembrane component 1	7814363	Evidence for Cu(II) reduction as a component of copper uptake by Saccharomyces cerevisiae.

Q9H2A7	CXL16_HUMAN	C-X-C motif chemokine 16	11060282	Molecular cloning of a novel scavenger receptor for oxidized low density lipoprotein, SR-PSOX, on macrophages.

P18671	LECB1_ARTIN	Agglutinin beta-1 chain	8673603	A novel mode of carbohydrate recognition in jacalin, a Moraceae plant lectin with a beta-prism fold.

O08543	EFNA5_MOUSE	Ephrin-A5	15107857	Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling.

Q5XIX0	DJC14_RAT	DnaJ homolog subfamily C member 14	11331877	Regulation of transport of the dopamine D1 receptor by a new membrane-associated ER protein.

Q9Y5P0	O51B4_HUMAN	Olfactory receptor 51B4	11121057	Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.

P62266	RS23_HUMAN	40S ribosomal protein S23	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

Q8VZI8	FTSHA_ARATH	ATP-dependent zinc metalloprotease FTSH 10, mitochondrial	14630971	Coordinated regulation and complex formation of yellow variegated1 and yellow variegated2, chloroplastic FtsH metalloproteases involved in the repair cycle of photosystem II in Arabidopsis thylakoid membranes.

Q9UPP1	PHF8_HUMAN	Histone lysine demethylase PHF8	20023638	Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.

P98174	FGD1_HUMAN	FYVE, RhoGEF and PH domain-containing protein 1	7954831	Isolation and characterization of the faciogenital dysplasia (Aarskog-Scott syndrome) gene: a putative Rho/Rac guanine nucleotide exchange factor.

O42636	CIA30_NEUCR	Complex I intermediate-associated protein 30, mitochondrial	9769214	Involvement of two novel chaperones in the assembly of mitochondrial NADH:ubiquinone oxidoreductase (complex 1).

Q63486	RRAGA_RAT	Ras-related GTP-binding protein A	7499430	Cloning of a novel family of mammalian GTP-binding proteins (RagA, RagBs, RagBl) with remote similarity to the Ras-related GTPases.

P48008	SPN3_SCHPO	Septin homolog spn3	15385632	Requirements of fission yeast septins for complex formation, localization, and function.

Q9XIE2	AB36G_ARATH	ABC transporter G family member 36	17355438	The ABC transporter AtPDR8 is a cadmium extrusion pump conferring heavy metal resistance.

P25522	MNME_ECOLI	tRNA modification GTPase mnmE	10601028	The Escherichia coli trmE (mnmE) gene, involved in tRNA modification, codes for an evolutionarily conserved GTPase with unusual biochemical properties.

P08525	QCR8_YEAST	Cytochrome b-c1 complex subunit 8	8394810	A region of the C-terminal part of the 11-kDa subunit of ubiquinol- cytochrome-c oxidoreductase of the yeast Saccharomyces cerevisiae contributes to the structure of the Qout reaction domain.

Q8SX83	SPEN_DROME	Protein split ends	10556062	spen encodes an RNP motif protein that interacts with Hox pathways to repress the development of head-like sclerites in the Drosophila trunk.

Q8K4E0	ALMS1_MOUSE	Alstrom syndrome protein 1 homolog	16000322	Alms1-disrupted mice recapitulate human Alstrom syndrome.

Q9UNN8	EPCR_HUMAN	Endothelial protein C receptor	7929370	Identification, cloning, and regulation of a novel endothelial cell protein C/activated protein C receptor.

Q07973	CP24A_HUMAN	1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	7632726	Cloning of the human 1 alpha,25-dihydroxyvitamin D-3 24-hydroxylase gene promoter and identification of two vitamin D-responsive elements.

P32521	PAN1_YEAST	Actin cytoskeleton-regulatory complex protein PAN1	8978817	A novel fluorescence-activated cell sorter-based screen for yeast endocytosis mutants identifies a yeast homologue of mammalian eps15.

Q12884	SEPR_HUMAN	Seprase	16651416	The protease complex consisting of dipeptidyl peptidase IV and seprase plays a role in the migration and invasion of human endothelial cells in collagenous matrices.

Q13724	MOGS_HUMAN	Mannosyl-oligosaccharide glucosidase	7635146	Cloning and expression of glucosidase I from human hippocampus.

Q9PVZ4	INSR_XENLA	Insulin receptor	1648732	Genes encoding receptors for insulin and insulin-like growth factor I are expressed in Xenopus oocytes and embryos.

O42601	S17B1_XENLA	Transcription factor Sox-17-beta.1	17719026	Regulation of the Xenopus Xsox17alpha(1) promoter by co-operating VegT and Sox17 sites.

Q8JFY9	ENDUA_XENLA	Poly(U)-specific endoribonuclease-A	12571235	Purification, cloning, and characterization of XendoU, a novel endoribonuclease involved in processing of intron-encoded small nucleolar RNAs in Xenopus laevis.

P36837	DTPB_ECOLI	Dipeptide and tripeptide permease B	18485005	DtpB (YhiP) and DtpA (TppB, YdgR) are prototypical proton-dependent peptide transporters of Escherichia coli.

P00830	ATPB_YEAST	ATP synthase subunit beta, mitochondrial	6225776	Nuclear genes coding the yeast mitochondrial adenosine triphosphatase complex. Isolation of ATP2 coding the F1-ATPase beta subunit.

Q93008	USP9X_HUMAN	Probable ubiquitin carboxyl-terminal hydrolase FAF-X	19135894	FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination.

Q99MV1	TDRD1_MOUSE	Tudor domain-containing protein 1	16787967	Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway?

P36044	MNN4_YEAST	Protein MNN4	9023541	Cloning and analysis of the MNN4 gene required for phosphorylation of N-linked oligosaccharides in Saccharomyces cerevisiae.

O65202	ACOX1_ARATH	Peroxisomal acyl-coenzyme A oxidase 1	10571860	Long-chain acyl-CoA oxidases of Arabidopsis.

Q9H2C0	GAN_HUMAN	Gigaxonin	16227972	Gigaxonin-controlled degradation of MAP1B light chain is critical to neuronal survival.

P38337	SHG1_YEAST	COMPASS component SHG1	11742990	The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4.

Q24573	DRI_DROME	Protein dead ringer	15576402	Drosophila retained/dead ringer is necessary for neuronal pathfinding, female receptivity and repression of fruitless independent male courtship behaviors.

P51955	NEK2_HUMAN	Serine/threonine-protein kinase Nek2	14978040	NEK2A interacts with MAD1 and possibly functions as a novel integrator of the spindle checkpoint signaling.

Q54QQ1	PHG2_DICDI	Serine/threonine-protein kinase phg2	15194808	Phg2, a kinase involved in adhesion and focal site modeling in Dictyostelium.

Q9UIV1	CNOT7_HUMAN	CCR4-NOT transcription complex subunit 7	9820826	Human carbon catabolite repressor protein (CCR4)-associative factor 1: cloning, expression and characterization of its interaction with the B-cell translocation protein BTG1.

Q8VE98	CD276_MOUSE	CD276 antigen	12925852	The B7 family member B7-H3 preferentially down-regulates T helper type 1-mediated immune responses.

Q7KHG2	JING_DROME	Zinc finger protein jing	12111212	The jing gene is required for embryonic brain development in Drosophila.

Q99727	TIMP4_HUMAN	Metalloproteinase inhibitor 4	8939999	Molecular cloning and characterization of human tissue inhibitor of metalloproteinase 4.

P92958	KIN11_ARATH	SNF1-related protein kinase catalytic subunit alpha KIN11	12148529	A novel higher plant protein tyrosine phosphatase interacts with SNF1-related protein kinases via a KIS (kinase interaction sequence) domain.

P32565	RPN2_YEAST	26S proteasome regulatory subunit RPN2	10688918	Physical association of ubiquitin ligases and the 26S proteasome.

P33757	SPO23_YEAST	Sporulation protein 23	17179081	Genetic evidence for a SPO1-dependent signaling pathway controlling meiotic progression in yeast.

Q7JW27	WASH1_DROME	WAS protein family homolog 1	19633175	Wash functions downstream of Rho and links linear and branched actin nucleation factors.

Q9LL45	TBP1_ORYSJ	Telomere-binding protein 1	19152316	Solution structure of the DNA binding domain of rice telomere binding protein RTBP1.

O14804	TAAR5_HUMAN	Trace amine-associated receptor 5	15718104	Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors.

P09440	C1TM_YEAST	C-1-tetrahydrofolate synthase, mitochondrial	3528153	Purification and characterization of a mitochondrial isozyme of C1- tetrahydrofolate synthase from Saccharomyces cerevisiae.

P30958	MFD_ECOLI	Transcription-repair-coupling factor	8465200	Molecular mechanism of transcription-repair-coupling.

O46339	HTH_DROME	Homeobox protein homothorax	14636555	Homothorax switches function of Drosophila photoreceptors from color to polarized light sensors.

Q94899	CSN2_DROME	COP9 signalosome complex subunit 2	10531038	The COP9 signalosome is essential for development of Drosophila melanogaster.

Q9UTL1	YIVF_SCHPO	Uncharacterized protein C144.15c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P30044	PRDX5_HUMAN	Peroxiredoxin-5, mitochondrial	10521424	Cloning and characterization of AOEB166, a novel mammalian antioxidant enzyme of the peroxiredoxin family.

Q13653	CO031_HUMAN	Putative uncharacterized protein C15orf31	8228263	Identification of human pre-T/NK cell-associated genes.

Q9HDV0	YHE5_SCHPO	Putative glutamine amidotransferase PB2B2.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UL54	TAOK2_HUMAN	Serine/threonine-protein kinase TAO2	10660600	PSK, a novel STE20-like kinase derived from prostatic carcinoma that activates the JNK MAPK pathway and regulates actin cytoskeletal organisation.

P87311	MUB1_SCHPO	MYND-type zinc finger protein C31F10.10c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q99720	SGMR1_HUMAN	Sigma non-opioid intracellular receptor 1	9453537	Exon-intron structure, analysis of promoter region, and chromosomal localization of the human type 1 sigma receptor gene.

Q969V5	MUL1_HUMAN	Mitochondrial ubiquitin ligase activator of NFKB 1	18591963	GIDE is a mitochondrial E3 ubiquitin ligase that induces apoptosis and slows growth.

P12004	PCNA_HUMAN	Proliferating cell nuclear antigen	18794347	PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex.

P52292	IMA2_HUMAN	Importin subunit alpha-2	8016130	Rch1, a protein that specifically interacts with the RAG-1 recombination-activating protein.

P55194	3BP1_MOUSE	SH3 domain-binding protein 1	8438166	Identification of a ten-amino acid proline-rich SH3 binding site.

Q06436	MAG2_YEAST	RING-finger protein MAG2	14562095	Global analysis of protein localization in budding yeast.

Q06828	FMOD_HUMAN	Fibromodulin	8093006	Interaction of the small interstitial proteoglycans biglycan, decorin and fibromodulin with transforming growth factor beta.

Q9Y2B1	TMEM5_HUMAN	Transmembrane protein 5	10072769	Selection of cDNAs encoding putative type II membrane proteins on the cell surface from a human full-length cDNA bank.

Q16512	PKN1_HUMAN	Serine/threonine-protein kinase N1	9478917	PRK1 is targeted to endosomes by the small GTPase, RhoB.

Q9Y5X9	LIPE_HUMAN	Endothelial lipase	10192396	A novel endothelial-derived lipase that modulates HDL metabolism.

Q06102	YTH1_YEAST	mRNA 3'-end-processing protein YTH1	12819204	Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-ends.

Q925H0	ACCN1_MOUSE	Amiloride-sensitive cation channel 1, neuronal	14762118	Acid-sensing ion channel 2 is important for retinal function and protects against light-induced retinal degeneration.

Q10752	CDC28_SCHPO	Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein cdc28	8862522	A connection between pre-mRNA splicing and the cell cycle in fission yeast: cdc28+ is allelic with prp8+ and encodes an RNA-dependent ATPase/helicase.

O94684	TFB3_SCHPO	RNA polymerase II transcription factor B subunit 3	15555586	Mcs2 and a novel CAK subunit Pmh1 associate with Skp1 in fission yeast.

P91641	MED20_DROME	Mediator of RNA polymerase II transcription subunit 20	12021283	Novel Mediator proteins of the small Mediator complex in Drosophila SL2 cells.

O14775	GBB5_HUMAN	Guanine nucleotide-binding protein subunit beta-5	9606987	Cloning and tissue distribution of the human G protein beta 5 cDNA.

Q7L523	RRAGA_HUMAN	Ras-related GTP-binding protein A	8995684	Interaction of an adenovirus 14.7-kilodalton protein inhibitor of tumor necrosis factor alpha cytolysis with a new member of the GTPase superfamily of signal transducers.

O60603	TLR2_HUMAN	Toll-like receptor 2	9435236	A family of human receptors structurally related to Drosophila Toll.

P38339	RGD1_YEAST	RHO GTPase-activating protein RGD1	10526184	The yeast Rgd1p is a GTPase activating protein of the Rho3 and rho4 proteins.

Q9P3A7	CDC48_SCHPO	Cell division cycle protein 48	15120077	The Ubx2 and Ubx3 cofactors direct Cdc48 activity to proteolytic and nonproteolytic ubiquitin-dependent processes.

Q9UIB8	SLAF5_HUMAN	SLAM family member 5	9310491	CD84 leukocyte antigen is a new member of the Ig superfamily.

Q92626	PXDN_HUMAN	Peroxidasin homolog	19590037	Peroxidasin is secreted and incorporated into the extracellular matrix of myofibroblasts and fibrotic kidney.

P82705	IM04_DROME	Immune-induced peptide 4	12171930	Peptidomics of the larval Drosophila melanogaster central nervous system.

Q9VK71	PDM2B_DROME	POU domain protein 2, isoform B	1496003	dOct2, a Drosophila Oct transcription factor that functions in yeast.

Q6RFH5	WDR74_HUMAN	WD repeat-containing protein 74	12429849	Functional proteomic analysis of human nucleolus.

P14925	AMD_RAT	Peptidyl-glycine alpha-amidating monooxygenase	9837933	P-CIP1, a novel protein that interacts with the cytosolic domain of peptidylglycine alpha-amidating monooxygenase, is associated with endosomes.

Q9Y4A0	JERKL_HUMAN	Jerky protein homolog-like	9240447	Cloning, mapping, and tissue distribution of a human homologue of the mouse jerky gene product.

Q00987	MDM2_HUMAN	E3 ubiquitin-protein ligase Mdm2	10608892	Stabilization of the MDM2 oncoprotein by interaction with the structurally related MDMX protein.

Q98SN7	WNT2B_CHICK	Protein Wnt-2b	10398532	Analysis of chicken Wnt-13 expression demonstrates coincidence with cell division in the developing eye and is consistent with a role in induction.

Q99M15	PPIP2_MOUSE	Proline-serine-threonine phosphatase-interacting protein 2	9804836	A novel macrophage actin-associated protein (MAYP) is tyrosine phosphorylated following colony stimulating factor-1 stimulation.

P60602	ROMO1_HUMAN	Reactive oxygen species modulator 1	18836179	Replicative senescence induced by Romo1-derived reactive oxygen species.

P31007	DLG1_DROME	Disks large 1 tumor suppressor protein	10884224	Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors.

P34689	GLH1_CAEEL	ATP-dependent RNA helicase glh-1	8943022	Multiple potential germ-line helicases are components of the germ- line-specific P granules of Caenorhabditis elegans.

P42836	PFA3_YEAST	Palmitoyltransferase PFA3	14562095	Global analysis of protein localization in budding yeast.

Q96Q89	KI20B_HUMAN	Kinesin-like protein KIF20B	11470801	Identification of a novel kinesin-related protein, KRMP1, as a target for mitotic peptidyl-prolyl isomerase Pin1.

Q92918	M4K1_HUMAN	Mitogen-activated protein kinase kinase kinase kinase 1	8824585	Human HPK1, a novel human hematopoietic progenitor kinase that activates the JNK/SAPK kinase cascade.

Q9UKR3	KLK13_HUMAN	Kallikrein-13	10766816	Identification and characterization of KLK-L4, a new kallikrein-like gene that appears to be down-regulated in breast cancer tissues.

P51142	DVL2_XENLA	Segment polarity protein dishevelled homolog DVL-2	16604063	Syndecan-4 regulates non-canonical Wnt signalling and is essential for convergent and extension movements in Xenopus embryos.

Q8C6B2	RTKN_MOUSE	Rhotekin	8662891	Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain.

Q04066	BNA7_YEAST	Probable kynurenine formamidase	18205391	Identification of formyl kynurenine formamidase and kynurenine aminotransferase from Saccharomyces cerevisiae using crystallographic, bioinformatic and biochemical evidence.

O74481	YQJ8_SCHPO	Uncharacterized protein C1840.08c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P38206	RFT1_YEAST	Oligosaccharide translocation protein RFT1	11807558	Translocation of lipid-linked oligosaccharides across the ER membrane requires Rft1 protein.

Q92997	DVL3_HUMAN	Segment polarity protein dishevelled homolog DVL-3	9344861	cDNA cloning of a human dishevelled DVL-3 gene, mapping to 3q27, and expression in human breast and colon carcinomas.

Q14683	SMC1A_HUMAN	Structural maintenance of chromosomes protein 1A	7757074	The human SB1.8 gene (DXS423E) encodes a putative chromosome segregation protein conserved in lower eukaryotes and prokaryotes.

Q8GXV7	CRR56_ARATH	Cysteine-rich repeat secretory protein 56	16287169	Arabidopsis cell wall proteome defined using multidimensional protein identification technology.

P32047	MLF3_YEAST	Protein MLF3	9805003	Saccharomyces cerevisiae MLF3/YNL074C gene, encoding a serine-rich protein of unknown function, determines the level of resistance to the novel immunosuppressive drug leflunomide.

P61285	DYL1_BOVIN	Dynein light chain 1, cytoplasmic	11967380	Subunit organization in cytoplasmic dynein subcomplexes.

Q9JK72	CCS_RAT	Copper chaperone for superoxide dismutase	10964676	Molecular cloning and characterization of a copper chaperone for copper/zinc superoxide dismutase from the rat.

P53835	PRM1_YEAST	Plasma membrane fusion protein PRM1	15590839	Prm1 prevents contact-dependent lysis of yeast mating pairs.

Q7D5T2	WBBL_MYCTU	dTDP-Rha:alpha-D-GlcNAc-pyrophosphate polyprenol, alpha-3-L-rhamnosyltransferase	15294902	Inactivation of the mycobacterial rhamnosyltransferase, which is needed for the formation of the arabinogalactan-peptidoglycan linker, leads to irreversible loss of viability.

P26367	PAX6_HUMAN	Paired box protein Pax-6	10441571	Missense mutation in the alternative splice region of the PAX6 gene in eye anomalies.

P56181	NDUV3_HUMAN	NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

Q92793	CBP_HUMAN	CREB-binding protein	10866662	A new family of nuclear receptor coregulators that integrates nuclear receptor signaling through CBP.

P43613	ERJ5_YEAST	ER-localized J domain-containing protein 5	14562095	Global analysis of protein localization in budding yeast.

P62948	RL41_RAT	60S ribosomal protein L41	7575549	The primary structures of rat ribosomal proteins L4 and L41.

Q9SE43	REV_ARATH	Homeobox-leucine zipper protein REVOLUTA	15598805	Class III homeodomain-leucine zipper gene family members have overlapping, antagonistic, and distinct roles in Arabidopsis development.

P24338	AREG_RAT	Amphiregulin	2234093	Structure, expression and function of a schwannoma-derived growth factor.

P04435	TVB2_HUMAN	T-cell receptor beta chain V region CTL-L17	2426193	The complete primary structure of the T-cell receptor genes from an alloreactive cytotoxic human T-lymphocyte clone.

P97947	NR0B2_RAT	Nuclear receptor subfamily 0 group B member 2	9003453	An orphan nuclear receptor lacking a zinc-finger DNA-binding domain: interaction with several nuclear receptors.

Q6PFP3	PDPFA_DANRE	Pancreatic progenitor cell differentiation and proliferation factor A	19067490	Exdpf is a key regulator of exocrine pancreas development controlled by retinoic acid and ptf1a in zebrafish.

O59702	CLR6_SCHPO	Histone deacetylase clr6	9755190	Histone deacetylase homologs regulate epigenetic inheritance of transcriptional silencing and chromosome segregation in fission yeast.

P38772	BCD1_YEAST	Box C/D snoRNA protein 1	14690591	Assigning function to yeast proteins by integration of technologies.

Q9D3R9	TAF7L_MOUSE	Transcription initiation factor TFIID subunit 7-like	12665565	The intracellular localisation of TAF7L, a paralogue of transcription factor TFIID subunit TAF7, is developmentally regulated during male germ-cell differentiation.

Q9VPQ6	USH_DROME	Zinc finger protein ush	9367989	U-shaped encodes a zinc finger protein that regulates the proneural genes achaete and scute during the formation of bristles in Drosophila.

Q8R2Q0	TRI29_MOUSE	Tripartite motif-containing protein 29	11331580	The tripartite motif family identifies cell compartments.

O94744	GIT3_SCHPO	Glucose receptor protein git3	11014802	Glucose monitoring in fission yeast via the gpa2 Galpha, the git5 Gbeta and the git3 putative glucose receptor.

Q500W7	PIGM_ARATH	GPI mannosyltransferase 1	15772281	Glycosylphosphatidylinositol-anchored proteins are required for cell wall synthesis and morphogenesis in Arabidopsis.

Q3E7A7	YK018_YEAST	Uncharacterized protein YKL018C-A	14562095	Global analysis of protein localization in budding yeast.

Q04637	IF4G1_HUMAN	Eukaryotic translation initiation factor 4 gamma 1	12086624	Recognition of eIF4G by rotavirus NSP3 reveals a basis for mRNA circularization.

Q03782	SNU56_YEAST	56 kDa U1 small nuclear ribonucleoprotein component	9630245	A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins.

Q9P2B2	FPRP_HUMAN	Prostaglandin F2 receptor negative regulator	11278880	The major CD9 and CD81 molecular partner. Identification and characterization of the complexes.

P0AC78	WECA_ECOLI	Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase	17237164	Functional characterization and membrane topology of Escherichia coli WecA, a sugar-phosphate transferase initiating the biosynthesis of enterobacterial common antigen and O-antigen lipopolysaccharide.

Q01543	FLI1_HUMAN	Friend leukemia integration 1 transcription factor	1522903	Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours.

P52422	PUR3_ARATH	Phosphoribosylglycinamide formyltransferase, chloroplastic	7920700	Molecular characterization of Arabidopsis thaliana cDNAs encoding three purine biosynthetic enzymes.

Q9VIP8	VLS_DROME	Protein valois	15800004	Valois, a component of the nuage and pole plasm, is involved in assembly of these structures, and binds to Tudor and the methyltransferase Capsuleen.

P08970	SUHW_DROME	Protein suppressor of hairy wing	7916729	A leucine zipper domain of the suppressor of Hairy-wing protein mediates its repressive effect on enhancer function.

P53847	DSL1_YEAST	Protein transport protein DSL1	11739780	Golgi-to-endoplasmic reticulum (ER) retrograde traffic in yeast requires Dsl1p, a component of the ER target site that interacts with a COPI coat subunit.

P22732	GTR5_HUMAN	Solute carrier family 2, facilitated glucose transporter member 5	1695905	Human facilitative glucose transporters. Isolation, functional characterization, and gene localization of cDNAs encoding an isoform (GLUT5) expressed in small intestine, kidney, muscle, and adipose tissue and an unusual glucose transporter pseudogene-like sequence (GLUT6).

Q8T638	DMTA_DICDI	Des-methyl DIF-1 methyltransferase A	9446571	The biosynthesis of differentiation-inducing factor, a chlorinated signal molecule regulating Dictyostelium development.

Q4PIR3	NSE2_SCHPO	E3 SUMO-protein ligase nse2	16478984	The Nse5-Nse6 dimer mediates DNA repair roles of the Smc5-Smc6 complex.

Q680Q4	SIZ1_ARATH	E3 SUMO-protein ligase SIZ1	18069938	The SUMO E3 ligase, AtSIZ1, regulates flowering by controlling a salicylic acid-mediated floral promotion pathway and through affects on FLC chromatin structure.

O94428	MU168_SCHPO	Meiotically up-regulated gene 168 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q7KRI2	LOLAL_DROME	Longitudinals lacking protein-like	12834867	Trl-GAGA directly interacts with lola like and both are part of the repressive complex of Polycomb group of genes.

P32333	MOT1_YEAST	TATA-binding protein-associated factor MOT1	9234740	Molecular analysis of the SNF2/SWI2 protein family member MOT1, an ATP-driven enzyme that dissociates TATA-binding protein from DNA.

Q8L5W8	PIL1_ARATH	Transcription factor PIL1	16565297	Identification of primary target genes of phytochrome signaling. Early transcriptional control during shade avoidance responses in Arabidopsis.

P47037	SMC3_YEAST	Structural maintenance of chromosomes protein 3	11983169	Molecular architecture of SMC proteins and the yeast cohesin complex.

P0C074	YSF3_YEAST	RDS3 complex subunit 10	16314500	Interactions of the yeast SF3b splicing factor.

Q9Z2S9	FLOT2_RAT	Flotillin-2	9858255	Identification of reggie-1 and reggie-2 as plasmamembrane-associated proteins which cocluster with activated GPI-anchored cell adhesion molecules in non-caveolar micropatches in neurons.

P48052	CBPA2_HUMAN	Carboxypeptidase A2	2920728	Purification and properties of five different forms of human procarboxypeptidases.

Q06707	SWC7_YEAST	SWR1-complex protein 7	14562095	Global analysis of protein localization in budding yeast.

Q6DDA1	DJC15_XENTR	DnaJ homolog subfamily C member 15	18472403	A functional screen for genes involved in Xenopus pronephros development.

O74480	YQJ7_SCHPO	Uncharacterized protein C1840.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12083	MLH3_YEAST	DNA mismatch repair protein MLH3	12200140	Supercomplex formation between Mlh1-Mlh3 and Sgs1-Top3 heterocomplexes in meiotic yeast cells.

P08913	ADA2A_HUMAN	Alpha-2A adrenergic receptor	2823383	Cloning, sequencing, and expression of the gene coding for the human platelet alpha 2-adrenergic receptor.

Q3ULF4	SPG7_MOUSE	Paraplegin	14722615	Axonal degeneration in paraplegin-deficient mice is associated with abnormal mitochondria and impairment of axonal transport.

P25009	PUC1_SCHPO	Cyclin puc1	8006074	Analysis of the Schizosaccharomyces pombe cyclin puc1: evidence for a role in cell cycle exit.

Q09330	MLO3_SCHPO	mRNA export protein mlo3	15990877	Homolog of BRCA2-interacting Dss1p and Uap56p link Mlo3p and Rae1p for mRNA export in fission yeast.

P08539	GPA1_YEAST	Guanine nucleotide-binding protein alpha-1 subunit	16839886	Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein alpha subunit at the endosome.

Q15583	TGIF1_HUMAN	Homeobox protein TGIF1	8537382	A novel homeobox protein which recognizes a TGT core and functionally interferes with a retinoid-responsive motif.

P32121	ARRB2_HUMAN	Beta-arrestin-2	15635042	Beta-arrestin 2-dependent angiotensin II type 1A receptor-mediated pathway of chemotaxis.

P15151	PVR_HUMAN	Poliovirus receptor	12759359	Recruitment of nectin-3 to cell-cell junctions through trans- heterophilic interaction with CD155, a vitronectin and poliovirus receptor that localizes to alpha(v)beta3 integrin-containing membrane microdomains.

P20606	SAR1_YEAST	Small COPII coat GTPase SAR1	14627716	Reconstitution of coat protein complex II (COPII) vesicle formation from cargo-reconstituted proteoliposomes reveals the potential role of GTP hydrolysis by Sar1p in protein sorting.

Q9Y4K4	M4K5_HUMAN	Mitogen-activated protein kinase kinase kinase kinase 5	9038372	A novel human SPS1/STE20 homologue, KHS, activates jun N-terminal kinase.

P06367	RS14A_YEAST	40S ribosomal protein S14-A	15590835	The small-subunit processome is a ribosome assembly intermediate.

Q7TSY8	SGOL2_MOUSE	Shugoshin-like 2	17205076	Mammalian SGO2 appears at the inner centromere domain and redistributes depending on tension across centromeres during meiosis II and mitosis.

Q9ZUX7	IPT2_ARATH	tRNA dimethylallyltransferase 2	17062755	Roles of Arabidopsis ATP/ADP isopentenyltransferases and tRNA isopentenyltransferases in cytokinin biosynthesis.

O14122	CUL4_SCHPO	Cullin-4	16127433	Ubiquitin ligase component Cul4 associates with Clr4 histone methyltransferase to assemble heterochromatin.

P45381	ACY2_HUMAN	Aspartoacylase	8252036	Cloning of the human aspartoacylase cDNA and a common missense mutation in Canavan disease.

Q6PEE3	RIR2B_MOUSE	Ribonucleoside-diphosphate reductase subunit M2 B	11517226	Mammalian p53R2 protein forms an active ribonucleotide reductase in vitro with the R1 protein, which is expressed both in resting cells in response to DNA damage and in proliferating cells.

Q9SK92	ATL15_ARATH	E3 ubiquitin-protein ligase ATL15	16339806	Genome analysis and functional characterization of the E2 and RING- type E3 ligase ubiquitination enzymes of Arabidopsis.

P41123	RL13_RAT	60S ribosomal protein L13	8198561	The primary structure of rat ribosomal protein L13.

A0A8M2	L14AA_XENLA	Protein LSM14 homolog A-A	17074753	RAP55, a cytoplasmic mRNP component, represses translation in Xenopus oocytes.

Q801G2	MPRAB_DANRE	Membrane progestin receptor alpha-B	12574519	Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes.

P53779	MK10_HUMAN	Mitogen-activated protein kinase 10	8654373	Selective interaction of JNK protein kinase isoforms with transcription factors.

P38077	ATPG_YEAST	ATP synthase subunit gamma, mitochondrial	7929329	Cloning of the yeast ATP3 gene coding for the gamma-subunit of F1 and characterization of atp3 mutants.

Q9LMA1	FMO1_ARATH	Probable flavin-containing monooxygenase 1	16856982	A role for a flavin-containing mono-oxygenase in resistance against microbial pathogens in Arabidopsis.

O95292	VAPB_HUMAN	Vesicle-associated membrane protein-associated protein B/C	9920726	Molecular cloning and characterization of mammalian homologues of vesicle-associated membrane protein-associated (VAMP-associated) proteins.

O14730	RIOK3_HUMAN	Serine/threonine-protein kinase RIO3	9602165	Isolation of the Aspergillus nidulans sudD gene and its human homologue.

Q05048	CSTF1_HUMAN	Cleavage stimulation factor subunit 1	1358884	A human polyadenylation factor is a G protein beta-subunit homologue.

P27661	H2AX_MOUSE	Histone H2A.x	19092802	WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity.

Q9SWG0	IVD_ARATH	Isovaleryl-CoA dehydrogenase, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q9SM23	ACBP1_ARATH	Acyl-CoA-binding domain-containing protein 1	10363372	Isolation of a gene encoding Arabidopsis membrane-associated acyl-CoA binding protein and immunolocalization of its gene product.

Q9Y2J2	E41L3_HUMAN	Band 4.1-like protein 3	9892180	A novel member of the NF2/ERM/4.1 superfamily with growth suppressing properties in lung cancer.

Q58576	PAN_METJA	Proteasome-activating nucleotidase	20019667	Interactions of PAN's C-termini with archaeal 20S proteasome and implications for the eukaryotic proteasome-ATPase interactions.

O59748	CTK2_SCHPO	CTD kinase subunit beta	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9SJJ3	BLH8_ARATH	BEL1-like homeodomain protein 8	15120075	Competence to respond to floral inductive signals requires the homeobox genes PENNYWISE and POUND-FOOLISH.

Q07869	PPARA_HUMAN	Peroxisome proliferator-activated receptor alpha	7684926	cDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator activated receptor.

Q99PZ6	OSPG_SHIFL	Protein kinase OspG	16162672	The Shigella flexneri effector OspG interferes with innate immune responses by targeting ubiquitin-conjugating enzymes.

Q8IW35	CEP97_HUMAN	Centrosomal protein of 97 kDa	19460342	Cep76, a centrosomal protein that specifically restrains centriole reduplication.

Q6W2J9	BCOR_HUMAN	BCL-6 corepressor	16943429	Polycomb group and SCF ubiquitin ligases are found in a novel BCOR complex that is recruited to BCL6 targets.

Q715S9	TXND3_RAT	Thioredoxin domain-containing protein 3	12909633	Cloning and developmental analysis of murid spermatid-specific thioredoxin-2 (SPTRX-2), a novel sperm fibrous sheath protein and autoantigen.

P61088	UBE2N_HUMAN	Ubiquitin-conjugating enzyme E2 N	16122702	ISG15 modification of ubiquitin E2 Ubc13 disrupts its ability to form thioester bond with ubiquitin.

Q07538	PRP4_SCHPO	Serine/threonine-protein kinase prp4	8371982	The fission yeast prp4+ gene involved in pre-mRNA splicing codes for a predicted serine/threonine kinase and is essential for growth.

Q8VI24	SATB2_MOUSE	DNA-binding protein SATB2	18255031	Satb2 is a postmitotic determinant for upper-layer neuron specification in the neocortex.

P02870	LEC_LENCU	Lectin	8364026	Crystal structure determination and refinement at 2.3-A resolution of the lentil lectin.

Q9ZQI8	NLTL2_ARATH	Non-specific lipid-transfer protein-like protein At2g13820	14517339	Proteomic analysis of glycosylphosphatidylinositol-anchored membrane proteins.

O75920	SERF1_HUMAN	Small EDRK-rich factor 1	9731538	Identification of a candidate modifying gene for spinal muscular atrophy by comparative genomics.

Q9C168	CAT1_NEUCR	Catalase-1	15342250	Unusual Cys-Tyr covalent bond in a large catalase.

P40009	YND1_YEAST	Golgi apyrase	14562095	Global analysis of protein localization in budding yeast.

Q86X83	COMD2_HUMAN	COMM domain-containing protein 2	15799966	COMMD proteins, a novel family of structural and functional homologs of MURR1.

Q9USY0	MU131_SCHPO	Meiotically up-regulated gene 131 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P97334	NKX23_MOUSE	Homeobox protein Nkx-2.3	12141427	NK-2 class homeobox genes and pharyngeal/oral patterning: Nkx2-3 is required for salivary gland and tooth morphogenesis.

O54839	EOMES_MOUSE	Eomesodermin homolog	10716450	Eomesodermin is required for mouse trophoblast development and mesoderm formation.

P36621	CAP_SCHPO	Adenylyl cyclase-associated protein	1550959	Genetic and biochemical analysis of the adenylyl cyclase-associated protein, cap, in Schizosaccharomyces pombe.

P35700	PRDX1_MOUSE	Peroxiredoxin-1	19766572	The antioxidant enzyme Prdx1 controls neuronal differentiation by thiol-redox-dependent activation of GDE2.

P38270	ATG14_YEAST	Autophagy-related protein 14	11157979	Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae.

P28496	LAC1_YEAST	Sphingosine N-acyltransferase LAC1	15692566	Lip1p: a novel subunit of acyl-CoA ceramide synthase.

P62995	TRA2B_HUMAN	Transformer-2 protein homolog beta	9546399	Human Tra2 proteins are sequence-specific activators of pre-mRNA splicing.

Q39123	ATHB8_ARATH	Homeobox-leucine zipper protein ATHB-8	15598805	Class III homeodomain-leucine zipper gene family members have overlapping, antagonistic, and distinct roles in Arabidopsis development.

P07900	HS90A_HUMAN	Heat shock protein HSP 90-alpha	12853476	Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system.

P30518	V2R_HUMAN	Vasopressin V2 receptor	1303257	Mutations in the V2 vasopressin receptor gene are associated with X- linked nephrogenic diabetes insipidus.

Q05481	ZNF91_HUMAN	Zinc finger protein 91	8467795	Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells.

Q8VDA1	CSTN2_RAT	Calsyntenin-2	12498782	The calsyntenins - a family of postsynaptic membrane proteins with distinct neuronal expression patterns.

P38575	UPK2_MOUSE	Uroplakin-2	8175808	Mammalian uroplakins. A group of highly conserved urothelial differentiation-related membrane proteins.

Q9ERR1	NDEL1_MOUSE	Nuclear distribution protein nudE-like 1	15208636	A NUDEL-dependent mechanism of neurofilament assembly regulates the integrity of CNS neurons.

Q9NVW2	RNF12_HUMAN	E3 ubiquitin-protein ligase RLIM	19945382	RNF12 is an X-encoded dose-dependent activator of X chromosome inactivation.

Q93Z04	PLY13_ARATH	Probable pectate lyase 13	12215508	PMR6, a pectate lyase-like gene required for powdery mildew susceptibility in Arabidopsis.

P29458	MCM4_SCHPO	DNA replication licensing factor mcm4	1454522	Fission yeast cdc21+ belongs to a family of proteins involved in an early step of chromosome replication.

Q6ZPF3	TIAM2_MOUSE	T-lymphoma invasion and metastasis-inducing protein 2	11707441	Characterization of STEF, a guanine nucleotide exchange factor for Rac1, required for neurite growth.

P56278	MTCP1_HUMAN	Protein p13 MTCP-1	8361760	MTCP-1: a novel gene on the human chromosome Xq28 translocated to the T cell receptor alpha/delta locus in mature T cell proliferations.

O80452	AMPD_ARATH	AMP deaminase	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

P40362	UTP18_YEAST	U3 small nucleolar RNA-associated protein 18	15590835	The small-subunit processome is a ribosome assembly intermediate.

P32605	RU1A_YEAST	U1 small nuclear ribonucleoprotein A	8849781	Characterization of yeast U1 snRNP A protein: identification of the N-terminal RNA binding domain (RBD) binding site and evidence that the C-terminal RBD functions in splicing.

Q6QNY1	BL1S2_HUMAN	Biogenesis of lysosome-related organelles complex 1 subunit 2	15381421	Characterization of Ceap-11 and Ceap-16, two novel splicing-variant- proteins, associated with centrosome, microtubule aggregation and cell proliferation.

O43813	LANC1_HUMAN	LanC-like protein 1	19528316	Structure of human lanthionine synthetase C-like protein 1 and its interaction with Eps8 and glutathione.

Q99706	KI2L4_HUMAN	Killer cell immunoglobulin-like receptor 2DL4	8946682	NK cell receptor gene of the KIR family with two IG domains but highest homology to KIR receptors with three IG domains.

P46586	HIS1_CANAL	ATP phosphoribosyltransferase	7489899	Cloning of the Candida albicans HIS1 gene by direct complementation of a C. albicans histidine auxotroph using an improved double-ARS shuttle vector.

P54789	ORC1_SCHPO	Origin recognition complex subunit 1	10535928	Identification and reconstitution of the origin recognition complex from Schizosaccharomyces pombe.

Q9M4A2	SPO11_ARATH	Meiotic recombination protein SPO11-1	17785529	ASY1 mediates AtDMC1-dependent interhomolog recombination during meiosis in Arabidopsis.

O15392	BIRC5_HUMAN	Baculoviral IAP repeat-containing protein 5	16239925	Survivin mediates targeting of the chromosomal passenger complex to the centromere and midbody.

Q96LA8	ANM6_HUMAN	Protein arginine N-methyltransferase 6	17898714	Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive.

Q96KP1	EXOC2_HUMAN	Exocyst complex component 2	19166349	Solution structure and dynamics of the small GTPase RalB in its active conformation: significance for effector protein binding.

Q4QXM3	PD5AA_XENLA	Sister chromatid cohesion protein PDS5 homolog A-A	15855230	Functional contribution of Pds5 to cohesin-mediated cohesion in human cells and Xenopus egg extracts.

P02528	CRGE_RAT	Gamma-crystallin E	6319707	Strict co-linearity of genetic and protein folding domains in an intragenically duplicated rat lens gamma-crystallin gene.

Q6P6T1	C1S_RAT	Complement C1s subcomponent	9524231	Molecular cloning of a cDNA encoding a serine protease homologous to complement Cls precursor from rat C6 glial cells and its expression during glial differentiation.

Q2L4W6	SPO5_SCHPO	Sporulation-specific protein 5	16896214	Spo5/Mug12, a putative meiosis-specific RNA-binding protein, is essential for meiotic progression and forms Mei2 dot-like nuclear foci.

P33891	TIP20_YEAST	Protein transport protein TIP20	8334998	The TIP1 gene of Saccharomyces cerevisiae encodes an 80 kDa cytoplasmic protein that interacts with the cytoplasmic domain of Sec20p.

Q9UBN1	CCG4_HUMAN	Voltage-dependent calcium channel gamma-4 subunit	10613843	Identification of three novel Ca(2+) channel gamma subunit genes reveals molecular diversification by tandem and chromosome duplication.

P81605	DCD_HUMAN	Dermcidin	9736629	Identification of a survival-promoting peptide in medium conditioned by oxidatively stressed cell lines of nervous system origin.

P53727	BUD17_YEAST	Putative pyridoxal kinase BUD17	14562095	Global analysis of protein localization in budding yeast.

Q02950	RT51_YEAST	37S ribosomal protein MRP51, mitochondrial	11278769	Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues.

O95376	ARI2_HUMAN	E3 ubiquitin-protein ligase ARIH2	16118314	The E3 ubiquitin-protein ligase Triad1 inhibits clonogenic growth of primary myeloid progenitor cells.

Q9BVC4	LST8_HUMAN	Target of rapamycin complex subunit LST8	15467718	Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive.

P08833	IBP1_HUMAN	Insulin-like growth factor-binding protein 1	2454104	Cloning, characterization, and expression of a human insulin-like growth factor binding protein.

Q9P0J0	NDUAD_HUMAN	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	15753091	GRIM-19 interacts with nucleotide oligomerization domain 2 and serves as downstream effector of anti-bacterial function in intestinal epithelial cells.

P84085	ARF5_HUMAN	ADP-ribosylation factor 5	1993656	Molecular identification of ADP-ribosylation factor mRNAs and their expression in mammalian cells.

Q15637	SF01_HUMAN	Splicing factor 1	7912130	Isolation and characterization of a novel gene encoding nuclear protein at a locus (D11S636) tightly linked to multiple endocrine neoplasia type 1 (MEN1).

P70500	CDIPT_RAT	CDP-diacylglycerol--inositol 3-phosphatidyltransferase	8804431	Molecular cloning of rat phosphatidylinositol synthase cDNA by functional complementation of the yeast Saccharomyces cerevisiae pis mutation.

Q17941	AKT1_CAEEL	Serine/threonine-protein kinase akt-1	9716402	Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor.

Q9SDS7	VATC_ARATH	V-type proton ATPase subunit C	10617574	The Arabidopsis det3 mutant reveals a central role for the vacuolar H(+)-ATPase in plant growth and development.

P46972	IMP2_YEAST	Mitochondrial inner membrane protease subunit 2	8266095	A mitochondrial protease with two catalytic subunits of nonoverlapping specificities.

P15384	KCNA3_RAT	Potassium voltage-gated channel subfamily A member 3	7477295	Clustering of Shaker-type K+ channels by interaction with a family of membrane-associated guanylate kinases.

P53094	MDS3_YEAST	Negative regulator of sporulation MDS3	9383076	Identification of a new class of negative regulators affecting sporulation-specific gene expression in yeast.

Q9USH2	YJH2_SCHPO	UPF0651 protein P31B10.02, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9VFK6	SETD8_DROME	Histone-lysine N-methyltransferase pr-set7	12086618	PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin.

Q9NSU2	TREX1_HUMAN	Three prime repair exonuclease 1	10391904	Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3'-->5' exonucleases.

Q13838	UAP56_HUMAN	Spliceosome RNA helicase BAT1	19836239	UIF, a new mRNA export adaptor that works together with REF/ALY, requires FACT for recruitment to mRNA.

Q8LG77	IDH6_ARATH	Isocitrate dehydrogenase [NAD] catalytic subunit 6, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P02586	TNNC2_RABIT	Troponin C, skeletal muscle	9560191	Crystal structure of troponin C in complex with troponin I fragment at 2.3-A resolution.

Q27128	PAPSS_URECA	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase	8522184	A multifunctional Urechis caupo protein, PAPS synthetase, has both ATP sulfurylase and APS kinase activities.

O61267	LOK_DROME	Ovarian-specific serine/threonine-protein kinase Lok	9507063	A novel Drosophila nuclear protein serine/threonine kinase expressed in the germline during its establishment.

Q9Y478	AAKB1_HUMAN	5'-AMP-activated protein kinase subunit beta-1	18403135	Identification and characterization of a novel folliculin-interacting protein FNIP2.

Q9ES52	SHIP1_MOUSE	Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1	9620849	Targeted disruption of SHIP leads to hemopoietic perturbations, lung pathology, and a shortened life span.

P77215	RHMD_ECOLI	L-rhamnonate dehydratase	18754693	Evolution of enzymatic activities in the enolase superfamily: L- rhamnonate dehydratase.

Q9QWG7	ST1B1_MOUSE	Sulfotransferase family cytosolic 1B member 1	9644246	Molecular cloning, expression, and characterization of a novel mouse liver SULT1B1 sulfotransferase.

P47169	ECM17_YEAST	Sulfite reductase [NADPH] subunit beta	9335584	Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae.

O94701	INN1_SCHPO	Ingression protein fic1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9W719	HPRT_CHICK	Hypoxanthine-guanine phosphoribosyltransferase	10198428	The chicken HPRT gene: a counter selectable marker for the DT40 cell line.

P61247	RS3A_HUMAN	40S ribosomal protein S3a	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

Q12988	HSPB3_HUMAN	Heat shock protein beta-3	9858786	HspB3, the most deviating of the six known human small heat shock proteins.

Q9LY41	ATL4_ARATH	E3 ubiquitin-protein ligase ATL4	15644464	Functional analysis of the RING-type ubiquitin ligase family of Arabidopsis.

P20263	PO5F1_MOUSE	POU domain, class 5, transcription factor 1	1972777	A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo.

Q9GZT5	WN10A_HUMAN	Protein Wnt-10a	17847007	Mutation in WNT10A is associated with an autosomal recessive ectodermal dysplasia: the odonto-onycho-dermal dysplasia.

Q61955	KLK8_MOUSE	Kallikrein-8	16537644	Role of neuropsin in formation and maturation of Schaffer-collateral L1cam-immunoreactive synaptic boutons.

P38815	YPT35_YEAST	PX domain-containing protein YPT35	14562095	Global analysis of protein localization in budding yeast.

Q6NXH3	GPBP1_MOUSE	Vasculin	14612417	The murine G+C-rich promoter binding protein mGPBP is required for promoter-specific transcription.

Q5G872	SCUB2_DANRE	Signal peptide, CUB and EGF-like domain-containing protein 2	15660164	The you gene encodes an EGF-CUB protein essential for Hedgehog signaling in zebrafish.

P46436	GST1_ASCSU	Glutathione S-transferase 1	8183318	Molecular cloning and expression of a cDNA encoding glutathione S- transferase from Ascaris suum.

Q12510	YD156_YEAST	WD repeat-containing protein YDL156W	14562095	Global analysis of protein localization in budding yeast.

O15294	OGT1_HUMAN	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit	9083068	O-linked GlcNAc transferase is a conserved nucleocytoplasmic protein containing tetratricopeptide repeats.

P49334	TOM22_YEAST	Mitochondrial import receptor subunit TOM22	9774667	Preprotein translocase of the outer mitochondrial membrane: molecular dissection and assembly of the general import pore complex.

Q14919	NC2A_HUMAN	Dr1-associated corepressor	8608938	Requirement of a corepressor for Dr1-mediated repression of transcription.

Q5TYW6	RSPH9_DANRE	Radial spoke head protein 9 homolog	19200523	Mutations in radial spoke head protein genes RSPH9 and RSPH4A cause primary ciliary dyskinesia with central-microtubular-pair abnormalities.

Q9H6Z4	RANB3_HUMAN	Ran-binding protein 3	11932251	Ran-binding protein 3 links Crm1 to the Ran guanine nucleotide exchange factor.

Q8BKX1	BAIP2_MOUSE	Brain-specific angiogenesis inhibitor 1-associated protein 2	10814512	Rho small G-protein-dependent binding of mDia to an Src homology 3 domain-containing IRSp53/BAIAP2.

P36589	CDC14_SCHPO	Cell division control protein 14	8334307	The Schizosaccharomyces pombe cdc14 gene is required for septum formation and can also inhibit nuclear division.

P06245	KAPB_YEAST	cAMP-dependent protein kinase type 2	3036373	Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase.

Q9SGY1	AB10B_ARATH	ABC transporter B family member 10	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q9ZT84	G3OX2_ARATH	Gibberellin 3-beta-dioxygenase 2	9836749	Phytochrome regulation and differential expression of gibberellin 3beta-hydroxylase genes in germinating Arabidopsis seeds.

Q9Y6B2	EID1_HUMAN	EP300-interacting inhibitor of differentiation 1	11073989	Cells degrade a novel inhibitor of differentiation with E1A-like properties upon exiting the cell cycle.

Q62833	GRK5_RAT	G protein-coupled receptor kinase 5	8626574	Involvement of G protein-coupled receptor kinase 5 in homologous desensitization of the thyrotropin receptor.

Q06411	SP382_YEAST	Pre-mRNA-splicing factor SPP382	14562095	Global analysis of protein localization in budding yeast.

P41695	BUB1_YEAST	Checkpoint serine/threonine-protein kinase BUB1	12769845	Requirement of Skp1-Bub1 interaction for kinetochore-mediated activation of the spindle checkpoint.

Q9FUJ3	CKX2_ARATH	Cytokinin dehydrogenase 2	14555694	Cytokinin-deficient transgenic Arabidopsis plants show multiple developmental alterations indicating opposite functions of cytokinins in the regulation of shoot and root meristem activity.

P70531	EF2K_RAT	Eukaryotic elongation factor 2 kinase	8663182	Cloning and expression of cDNA encoding protein synthesis elongation factor-2 kinase.

P28229	CXG1_MOUSE	Gap junction gamma-1 protein	19864490	Consortin, a trans-Golgi network cargo receptor for the plasma membrane targeting and recycling of connexins.

Q10199	IMP2_SCHPO	Septation protein imp2	9786952	imp2, a new component of the actin ring in the fission yeast Schizosaccharomyces pombe.

Q9BDB7	IF44L_MOUSE	Interferon-induced protein 44-like	11021531	Differences that matter: major cytotoxic T cell-stimulating minor histocompatibility antigens.

O73694	EGR1_SERCA	Early growth response protein 1	9501495	Evolutionary conservation of the immediate-early gene ZENK.

Q5T230	UTF1_HUMAN	Undifferentiated embryonic cell transcription factor 1	9748258	Characterization of functional domains of an embryonic stem cell coactivator UTF1 which are conserved and essential for potentiation of ATF-2 activity.

P40222	TXLNA_HUMAN	Alpha-taxilin	8327514	Identification of a cDNA for a human high-molecular-weight B-cell growth factor.

Q6P5S7	RNK_HUMAN	Ribonuclease kappa	17881363	Molecular cloning and characterization of the human RNase kappa, an ortholog of Cc RNase.

P50336	PPOX_HUMAN	Protoporphyrinogen oxidase	8771201	Human protoporphyrinogen oxidase: expression, purification, and characterization of the cloned enzyme.

Q9ES17	IL21_MOUSE	Interleukin-21	11081504	Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function.

Q61006	MUSK_MOUSE	Muscle, skeletal receptor tyrosine-protein kinase	16794080	The muscle protein Dok-7 is essential for neuromuscular synaptogenesis.

P46964	OST2_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2	16297388	Yeast oligosaccharyltransferase consists of two functionally distinct sub-complexes, specified by either the Ost3p or Ost6p subunit.

P32472	FKBP2_YEAST	Peptidyl-prolyl cis-trans isomerase FPR2	1380159	Yeast FKBP-13 is a membrane-associated FK506-binding protein encoded by the nonessential gene FKB2.

Q12517	DCP1_YEAST	mRNA-decapping enzyme subunit 1	12730603	Decapping and decay of messenger RNA occur in cytoplasmic processing bodies.

Q0WPQ2	ETR2_ARATH	Ethylene receptor 2	15703053	Ethylene-binding activity, gene expression levels, and receptor system output for ethylene receptor family members from Arabidopsis and tomato.

P33411	PRP18_YEAST	Pre-mRNA-splicing factor 18	8474454	A U5 small nuclear ribonucleoprotein particle protein involved only in the second step of pre-mRNA splicing in Saccharomyces cerevisiae.

O57428	HASR_XENLA	Hyaluronan synthase-related protein	9442026	Characterization and molecular evolution of a vertebrate hyaluronan synthase gene family.

Q9I7I0	CCNB3_DROME	G2/mitotic-specific cyclin-B3	9851980	Drosophila Cyclin B3 is required for female fertility and is dispensable for mitosis like Cyclin B.

Q13618	CUL3_HUMAN	Cullin-3	17543862	A Cul3-based E3 ligase removes Aurora B from mitotic chromosomes, regulating mitotic progression and completion of cytokinesis in human cells.

P0A9M0	LON_ECOLI	Lon protease	15037242	Crystal structure of the AAA+ alpha domain of E. coli Lon protease at 1.9A resolution.

Q6IE81	JADE1_HUMAN	Protein Jade-1	12169691	The von Hippel-Lindau tumor suppressor stabilizes novel plant homeodomain protein Jade-1.

Q12906	ILF3_HUMAN	Interleukin enhancer-binding factor 3	8885239	Identification of novel M phase phosphoproteins by expression cloning.

O43052	RGA1_SCHPO	Rho-type GTPase-activating protein 1	11737264	Characterization of GTPase-activating proteins for the function of the Rho-family small GTPases in the fission yeast Schizosaccharomyces pombe.

P75993	ARIR_ECOLI	Probable two-component-system connector protein AriR	17765265	Structure and function of the Escherichia coli protein YmgB: a protein critical for biofilm formation and acid-resistance.

Q9FLI3	P2C75_ARATH	Probable protein phosphatase 2C 75	17461784	ABA-Hypersensitive Germination1 encodes a protein phosphatase 2C, an essential component of abscisic acid signaling in Arabidopsis seed.

Q92496	FHR4_HUMAN	Complement factor H-related protein 4	9038172	The human factor H-related protein 4 (FHR-4). A novel short consensus repeat-containing protein is associated with human triglyceride-rich lipoproteins.

O61492	FLOT2_DROME	Flotillin-2	9573373	Identification, sequence and developmental expression of invertebrate flotillins from Drosophila melanogaster.

P22304	IDS_HUMAN	Iduronate 2-sulfatase	2122463	Hunter syndrome: isolation of an iduronate-2-sulfatase cDNA clone and analysis of patient DNA.

O14582	TPPC2_HUMAN	Trafficking protein particle complex subunit 2	11134351	A novel 16-kilodalton cellular protein physically interacts with and antagonizes the functional activity of c-myc promoter-binding protein 1.

Q99JH7	CSTN3_MOUSE	Calsyntenin-3	12498782	The calsyntenins - a family of postsynaptic membrane proteins with distinct neuronal expression patterns.

P98170	XIAP_HUMAN	Baculoviral IAP repeat-containing protein 4	11257231	Structural basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain.

Q924S8	SPRE1_MOUSE	Sprouty-related, EVH1 domain-containing protein 1	12646235	Molecular cloning of mammalian Spred-3 which suppresses tyrosine kinase-mediated Erk activation.

Q8H136	RH14_ARATH	DEAD-box ATP-dependent RNA helicase 14	9592148	Characterization of a DEAD box ATPase/RNA helicase protein of Arabidopsis thaliana.

Q9USL5	DOM34_SCHPO	Protein dom34	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12494	KCS1_YEAST	Inositol hexakisphosphate kinase 1	10574768	Synthesis of diphosphoinositol pentakisphosphate by a newly identified family of higher inositol polyphosphate kinases.

Q08558	DCI1_YEAST	Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase	10381339	Preliminary characterization of Yor180Cp: identification of a novel peroxisomal protein of Saccharomyces cerevisiae involved in fatty acid metabolism.

A8MRX0	GSOX5_ARATH	Flavin-containing monooxygenase FMO GS-OX5	18799661	Subclade of flavin-monooxygenases involved in aliphatic glucosinolate biosynthesis.

P20701	ITAL_HUMAN	Integrin alpha-L	2537322	Primary structure of the leukocyte function-associated molecule-1 alpha subunit: an integrin with an embedded domain defining a protein superfamily.

Q9I7D3	CAPR1_DROME	Caprin homolog	16979555	The lipid-droplet proteome reveals that droplets are a protein- storage depot.

Q50HP4	DAD4_SCHPO	DASH complex subunit dad4	16079914	Molecular analysis of kinetochore architecture in fission yeast.

Q9UBT7	CTNL1_HUMAN	Alpha-catulin	12270917	Association of Lbc Rho guanine nucleotide exchange factor with alpha- catenin-related protein, alpha-catulin/CTNNAL1, supports serum response factor activation.

P33313	CNS1_YEAST	Hsp70/Hsp90 co-chaperone CNS1	15044454	Cns1 is an activator of the Ssa1 ATPase activity.

Q8AWW7	RUVB1_DANRE	RuvB-like 1	12464178	Reptin and pontin antagonistically regulate heart growth in zebrafish embryos.

Q9GT24	ZYG1_CAEEL	Probable serine/threonine-protein kinase zyg-1	11371350	The C. elegans zyg-1 gene encodes a regulator of centrosome duplication with distinct maternal and paternal roles in the embryo.

Q80YE4	LMTK1_MOUSE	Serine/threonine-protein kinase LMTK1	9444961	AATYK: a novel tyrosine kinase induced during growth arrest and apoptosis of myeloid cells.

P19087	GNAT2_HUMAN	Guanine nucleotide-binding protein G(t) subunit alpha-2	12077706	Mutations in the cone photoreceptor G-protein alpha-subunit gene GNAT2 in patients with achromatopsia.

P30121	TIMP2_RAT	Metalloproteinase inhibitor 2	8792217	Purification, cDNA cloning, and developmental changes in the steady- state mRNA level of rat testicular tissue inhibitor of metalloproteases-2 (TIMP-2).

Q9R037	WDR44_RAT	WD repeat-containing protein 44	10464283	Rab11BP/Rabphilin-11, a downstream target of rab11 small G protein implicated in vesicle recycling.

P22459	KCNA4_HUMAN	Potassium voltage-gated channel subfamily A member 4	2001794	Molecular cloning and characterization of two voltage-gated K+ channel cDNAs from human ventricle.

Q60769	TNAP3_MOUSE	Tumor necrosis factor alpha-induced protein 3	10385526	The zinc finger protein A20 inhibits TNF-induced NF-B-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-B-inhibiting protein ABIN.

Q54F44	NOXC_DICDI	Superoxide-generating NADPH oxidase heavy chain subunit C	15950752	NADPH oxidase homologs are required for normal cell differentiation and morphogenesis in Dictyostelium discoideum.

P23871	HEMH_ECOLI	Ferrochelatase	8056770	Overproduction, purification, and characterization of ferrochelatase from Escherichia coli.

Q9NEW6	RSP3_CAEEL	Probable splicing factor, arginine/serine-rich 3	11091073	SPK-1, a C. elegans SR protein kinase homologue, is essential for embryogenesis and required for germline development.

Q9URX9	PXR1_SCHPO	Protein pxr1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P38836	ECM14_YEAST	Protein ECM14	9335584	Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae.

Q90XW6	IRX4A_XENLA	Iroquois-class homeodomain protein irx-4-A	19268445	The Xenopus Irx genes are essential for neural patterning and define the border between prethalamus and thalamus through mutual antagonism with the anterior repressors Fezf and Arx.

Q9UTN3	CID14_SCHPO	Poly(A) RNA polymerase cid14	16478992	Requirement of fission yeast Cid14 in polyadenylation of rRNAs.

P47239	PAX7_MOUSE	Paired box protein Pax-7	11030621	Pax7 is required for the specification of myogenic satellite cells.

P46736	BRCC3_HUMAN	Lys-63-specific deubiquitinase BRCC36	17525341	RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites.

P61081	UBC12_HUMAN	NEDD8-conjugating enzyme Ubc12	9694792	A new NEDD8-ligating system for cullin-4A.

O14686	MLL2_HUMAN	Histone-lysine N-methyltransferase MLL2	9247308	Structure and expression pattern of human ALR, a novel gene with strong homology to ALL-1 involved in acute leukemia and to Drosophila trithorax.

Q8C8H8	KY_MOUSE	Kyphoscoliosis peptidase	11136708	The kyphoscoliosis (ky) mouse is deficient in hypertrophic responses and is caused by a mutation in a novel muscle-specific protein.

Q9BV10	ALG12_HUMAN	Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase	12217961	ALG12 mannosyltransferase defect in congenital disorder of glycosylation type Ig.

Q60700	M3K12_MOUSE	Mitogen-activated protein kinase kinase kinase 12	7983011	Identification, molecular cloning, and characterization of dual leucine zipper bearing kinase. A novel serine/threonine protein kinase that defines a second subfamily of mixed lineage kinases.

O95718	ERR2_HUMAN	Steroid hormone receptor ERR2	12654265	Monomeric complex of human orphan estrogen related receptor-2 with DNA: a pseudo-dimer interface mediates extended half-site recognition.

Q24533	DICH_DROME	SOX domain-containing protein dichaete	8951062	The Drosophila fish-hook gene encodes a HMG domain protein essential for segmentation and CNS development.

Q9SIY7	PR1B2_ARATH	PRA1 family protein B2	18583532	The PRA1 gene family in Arabidopsis.

Q969V5	MUL1_HUMAN	Mitochondrial ubiquitin ligase activator of NFKB 1	12761501	Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.

Q9H3D4	P63_HUMAN	Tumor protein 63	12446779	A C-terminal inhibitory domain controls the activity of p63 by an intramolecular mechanism.

Q92372	RFA1_SCHPO	Replication factor A protein 1	8702843	Purification, gene cloning, and reconstitution of the heterotrimeric single-stranded DNA-binding protein from Schizosaccharomyces pombe.

Q92743	HTRA1_HUMAN	Serine protease HTRA1	9852107	Human HtrA, an evolutionarily conserved serine protease identified as a differentially expressed gene product in osteoarthritic cartilage.

P87155	MUG16_SCHPO	Protein GMH1 homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P31943	HNRH1_HUMAN	Heterogeneous nuclear ribonucleoprotein H	16946708	Interaction of muscleblind, CUG-BP1 and hnRNP H proteins in DM1- associated aberrant IR splicing.

Q12280	IQG1_YEAST	Ras GTPase-activating-like protein IQG1	9442111	Sequential assembly of myosin II, an IQGAP-like protein, and filamentous actin to a ring structure involved in budding yeast cytokinesis.

Q62219	TGFI1_MOUSE	Transforming growth factor beta-1-induced transcript 1 protein	9756887	Interaction of Hic-5, A senescence-related protein, with focal adhesion kinase.

Q9I926	FUCL6_ANGJA	Fucolectin-6	10924498	Multiplicity, structures, and endocrine and exocrine natures of eel fucose-binding lectins.

Q9XZF0	YIPP_DROME	Protein yippee	11240639	The Drosophila gene Yippee reveals a novel family of putative zinc binding proteins highly conserved among eukaryotes.

Q13105	ZBT17_HUMAN	Zinc finger and BTB domain-containing protein 17	12244100	Host cell factor-1 interacts with and antagonizes transactivation by the cell cycle regulatory factor Miz-1.

P60390	RSMH_ECOLI	Ribosomal RNA small subunit methyltransferase H	19965768	Fine-tuning of the ribosomal decoding center by conserved methyl- modifications in the Escherichia coli 16S rRNA.

Q07362	PBP4_YEAST	Protein PBP4	14562095	Global analysis of protein localization in budding yeast.

Q03674	PLB2_YEAST	Lysophospholipase 2	15781460	Comprehensive proteomic analysis of Saccharomyces cerevisiae cell walls: identification of proteins covalently attached via glycosylphosphatidylinositol remnants or mild alkali-sensitive linkages.

P53299	TIM13_YEAST	Mitochondrial import inner membrane translocase subunit TIM13	10469659	Different import pathways through the mitochondrial intermembrane space for inner membrane proteins.

P48349	14336_ARATH	14-3-3-like protein GF14 lambda	15592873	The Arabidopsis SERK1 protein interacts with the AAA-ATPase AtCDC48, the 14-3-3 protein GF14lambda and the PP2C phosphatase KAPP.

Q6J5K9	ARMI_DROME	Probable RNA helicase armi	15035984	The Drosophila SDE3 homolog armitage is required for oskar mRNA silencing and embryonic axis specification.

Q16822	PCKGM_HUMAN	Phosphoenolpyruvate carboxykinase [GTP], mitochondrial	8645161	Molecular cloning, sequencing and expression of the cDNA of the mitochondrial form of phosphoenolpyruvate carboxykinase from human liver.

O95168	NDUB4_HUMAN	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4	9878551	cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed.

Q91765	FXA2A_XENLA	Forkhead box protein A2-A	14697355	Inhibition of mesodermal fate by Xenopus HNF3beta/FoxA2.

P61244	MAX_HUMAN	Protein max	2006410	Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc.

P11940	PABP1_HUMAN	Polyadenylate-binding protein 1	11172725	Translational repression by a novel partner of human poly(A) binding protein, Paip2.

Q86W47	KCMB4_HUMAN	Calcium-activated potassium channel subunit beta-4	10692449	Cloning and functional characterization of novel large conductance calcium-activated potassium channel beta subunits, hKCNMB3 and hKCNMB4.

P22936	APN1_YEAST	DNA-(apurinic or apyrimidinic site) lyase 1	1693433	Yeast structural gene (APN1) for the major apurinic endonuclease: homology to Escherichia coli endonuclease IV.

P18886	CPT2_RAT	Carnitine O-palmitoyltransferase 2, mitochondrial	16615913	The crystal structure of carnitine palmitoyltransferase 2 and implications for diabetes treatment.

Q23405	HIM14_CAEEL	MutS protein homolog him-14	3224814	Maternal-effect lethal mutations on linkage group II of Caenorhabditis elegans.

Q1WG82	ZGLP1_MOUSE	GATA-type zinc finger protein 1	16982049	GLP-1: a novel zinc finger protein required in somatic cells of the gonad for germ cell development.

Q6PCD5	RFWD3_HUMAN	E3 ubiquitin-protein ligase RFWD3	20173098	RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage.

P25299	RNA15_YEAST	mRNA 3'-end-processing protein RNA15	11344258	Five subunits are required for reconstitution of the cleavage and polyadenylation activities of Saccharomyces cerevisiae cleavage factor I.

P40343	VPS27_YEAST	Vacuolar protein sorting-associated protein 27	12055639	The Vps27p-Hse1p complex binds ubiquitin and mediates endosomal protein sorting.

P20226	TBP_HUMAN	TATA-box-binding protein	2194289	Cloning of a transcriptionally active human TATA binding factor.

Q9CQM9	GLRX3_MOUSE	Glutaredoxin-3	18258855	PICOT attenuates cardiac hypertrophy by disrupting calcineurin-NFAT signaling.

P02545	LMNA_HUMAN	Prelamin-A/C	3453101	Homologies in both primary and secondary structure between nuclear envelope and intermediate filament proteins.

Q24255	BARH1_DROME	Homeobox protein B-H1	1346120	Dual Bar homeo box genes of Drosophila required in two photoreceptor cells, R1 and R6, and primary pigment cells for normal eye development.

P40518	ARPC5_YEAST	Actin-related protein 2/3 complex subunit 5	9210376	The complex containing actin-related proteins Arp2 and Arp3 is required for the motility and integrity of yeast actin patches.

Q9Z0L3	OC90_MOUSE	Otoconin-90	9892667	Characterization of otoconin-95, the major protein of murine otoconia, provides insights into the formation of these inner ear biominerals.

Q96IZ0	PAWR_HUMAN	PRKC apoptosis WT1 regulator protein	11585763	Par-4 drives trafficking and activation of Fas and Fasl to induce prostate cancer cell apoptosis and tumor regression.

Q05123	ARP9_YEAST	Actin-like protein ARP9	9844636	Two actin-related proteins are shared functional components of the chromatin-remodeling complexes RSC and SWI/SNF.

O54943	PER2_MOUSE	Period circadian protein homolog 2	19414593	Casein kinase 1 delta regulates the pace of the mammalian circadian clock.

P46091	GPR1_HUMAN	Probable G-protein coupled receptor 1	7851889	Cloning of human genes encoding novel G protein-coupled receptors.

P35269	T2FA_HUMAN	General transcription factor IIF subunit 1	7667268	Evolutionary conservation of human TATA-binding-polypeptide- associated factors TAFII31 and TAFII80 and interactions of TAFII80 with other TAFs and with general transcription factors.

Q9FKB5	KRP3_ARATH	Cyclin-dependent kinase inhibitor 3	16376885	Arabidopsis KRPs have distinct inhibitory activity toward cyclin D2- associated kinases, including plant-specific B-type cyclin-dependent kinase.

P46937	YAP1_HUMAN	Yorkie homolog	17974916	Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control.

P27466	KCC1_YEAST	Calcium/calmodulin-dependent protein kinase I	2061341	Two yeast genes encoding calmodulin-dependent protein kinases. Isolation, sequencing and bacterial expressions of CMK1 and CMK2.

P10902	NADB_ECOLI	L-aspartate oxidase	2841129	Molecular biology of pyridine nucleotide biosynthesis in Escherichia coli. Cloning and characterization of quinolinate synthesis genes nadA and nadB.

Q9Y666	S12A7_HUMAN	Solute carrier family 12 member 7	10347194	Cloning and characterization of KCC3 and KCC4, new members of the cation-chloride cotransporter gene family.

Q9EPI2	GFRA4_RAT	GDNF family receptor alpha-4	10958791	Mammalian GFRalpha-4, a divergent member of the GFRalpha family of coreceptors for Glial cell line-derived neurotrophic factor family ligands, is a receptor for the neurotrophic factor persephin.

Q9UGJ0	AAKG2_HUMAN	5'-AMP-activated protein kinase subunit gamma-2	10698692	Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding.

P70196	TRAF6_MOUSE	TNF receptor-associated factor 6	15322147	TNFR-associated factor (TRAF) 6 is essential for MyD88-dependent pathway but not toll/IL-1 receptor domain-containing adaptor-inducing IFN-beta (TRIF)-dependent pathway in TLR signaling.

Q9Y240	CLC11_HUMAN	C-type lectin domain family 11 member A	9705843	Isolation and characterization of a cDNA for human, mouse, and rat full-length stem cell growth factor, a new member of C-type lectin superfamily.

P49088	ASNS_RAT	Asparagine synthetase [glutamine-hydrolyzing]	7818476	Cloning of rat asparagine synthetase and specificity of the amino acid-dependent control of its mRNA content.

P48523	CADH4_ARATH	Cinnamyl alcohol dehydrogenase 4	12805615	Expression pattern of two paralogs encoding cinnamyl alcohol dehydrogenases in Arabidopsis. Isolation and characterization of the corresponding mutants.

Q9JJ16	5HT3B_RAT	5-hydroxytryptamine receptor 3B	10854267	Evidence for expression of heteromeric serotonin 5-HT(3) receptors in rodents.

Q05027	TAF9_YEAST	Transcription initiation factor TFIID subunit 9	9674426	A subset of TAF(II)s are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulation.

Q9LDC0	FKB42_ARATH	42 kDa peptidyl-prolyl isomerase	15133126	Arabidopsis immunophilin-like TWD1 functionally interacts with vacuolar ABC transporters.

P56705	WNT4_HUMAN	Protein Wnt-4	18182450	Identification and functional analysis of a new WNT4 gene mutation among 28 adolescent girls with primary amenorrhea and Muellerian duct abnormalities: a French collaborative study.

A1Z6W3	PRIC1_DROME	Protein prickle	12015986	Prickle mediates feedback amplification to generate asymmetric planar cell polarity signaling.

Q9VEC1	MED17_DROME	Mediator of RNA polymerase II transcription subunit 17	12021283	Novel Mediator proteins of the small Mediator complex in Drosophila SL2 cells.

O36024	FTA1_SCHPO	Kinetochore protein fta1	16079914	Molecular analysis of kinetochore architecture in fission yeast.

P13056	NR2C1_HUMAN	Nuclear receptor subfamily 2 group C member 1	3421977	Identification of a new member of the steroid receptor super-family by cloning and sequence analysis.

Q9VNB5	OR83B_DROME	Odorant receptor 83b	15339651	Or83b encodes a broadly expressed odorant receptor essential for Drosophila olfaction.

P54121	AIG2_ARATH	Protein AIG2	8742710	Isolation of Arabidopsis genes that differentiate between resistance responses mediated by the RPS2 and RPM1 disease resistance genes.

Q9H1B5	XYLT2_HUMAN	Xylosyltransferase 2	11099377	Molecular cloning and expression of human UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase and its first isoform XT-II.

P20393	NR1D1_HUMAN	Nuclear receptor subfamily 1 group D member 1	1971514	Isolation of a cDNA encoding human Rev-ErbA alpha: transcription from the noncoding DNA strand of a thyroid hormone receptor gene results in a related protein that does not bind thyroid hormone.

Q8LNV6	CKX3_ORYSJ	Cytokinin dehydrogenase 3	12721786	Structure and function of cytokinin oxidase/dehydrogenase genes of maize, rice, Arabidopsis and other species.

P43489	TNR4_HUMAN	Tumor necrosis factor receptor superfamily member 4	7510240	The human OX40 homolog: cDNA structure, expression and chromosomal assignment of the ACT35 antigen.

P78820	ACAC_SCHPO	Acetyl-CoA carboxylase	8769419	Aberrant mitosis in fission yeast mutants defective in fatty acid synthetase and acetyl CoA carboxylase.

Q23229	XOL1_CAEEL	XO lethal protein 1	3167975	xol-1: a gene that controls the male modes of both sex determination and X chromosome dosage compensation in C. elegans.

Q12743	DFM1_YEAST	DER1-like family member protein 1	14562095	Global analysis of protein localization in budding yeast.

P53261	PESC_YEAST	Pescadillo homolog	16888624	TOR regulates late steps of ribosome maturation in the nucleoplasm via Nog1 in response to nutrients.

O15943	CADN_DROME	Neural-cadherin	9635189	Roles of Armadillo, a Drosophila catenin, during central nervous system development.

P29317	EPHA2_HUMAN	Ephrin type-A receptor 2	2174105	cDNA cloning and characterization of eck, an epithelial cell receptor protein-tyrosine kinase in the eph/elk family of protein kinases.

Q1W695	A21_LOXIN	Sphingomyelin phosphodiesterase D LiSicTox-alphaII1	17296256	Two novel dermonecrotic toxins LiRecDT4 and LiRecDT5 from Brown spider (Loxosceles intermedia) venom: from cloning to functional characterization.

O75746	CMC1_HUMAN	Calcium-binding mitochondrial carrier protein Aralar1	9722566	Molecular cloning of Aralar, a new member of the mitochondrial carrier superfamily that binds calcium and is present in human muscle and brain.

Q92888	ARHG1_HUMAN	Rho guanine nucleotide exchange factor 1	10747909	Galpha 13 requires palmitoylation for plasma membrane localization, Rho-dependent signaling, and promotion of p115-RhoGEF membrane binding.

Q12754	RRP12_YEAST	Ribosomal RNA-processing protein 12	14729571	A pre-ribosome-associated HEAT-repeat protein is required for export of both ribosomal subunits.

O43264	ZW10_HUMAN	Centromere/kinetochore protein zw10 homolog	15485811	Human Zwint-1 specifies localization of Zeste White 10 to kinetochores and is essential for mitotic checkpoint signaling.

Q9VW15	ASH1_DROME	Histone-lysine N-methyltransferase ash1	10656681	Self-association of the SET domains of human ALL-1 and of Drosophila TRITHORAX and ASH1 proteins.

O95789	ZMYM6_HUMAN	Zinc finger MYM-type protein 6	10486218	Cloning and mapping of members of the MYM family.

Q9P3V4	YHEF_SCHPO	VEL1-related protein BPB2B2.15/BC1348.06c	18203864	Response of Schizosaccharomyces pombe to zinc deficiency.

Q6S5L9	SHC4_MOUSE	SHC-transforming protein 4	17452444	Analysis of a Shc family adaptor protein, ShcD/Shc4, that associates with muscle-specific kinase.

O43683	BUB1_HUMAN	Mitotic checkpoint serine/threonine-protein kinase BUB1	19487456	Bub1 regulates chromosome segregation in a kinetochore-independent manner.

P35968	VGFR2_HUMAN	Vascular endothelial growth factor receptor 2	1417831	Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor.

Q9W261	RTF1_DROME	RNA polymerase-associated protein Rtf1	16882721	Drosophila Rtf1 functions in histone methylation, gene expression, and Notch signaling.

Q924V4	S15A3_RAT	Solute carrier family 15 member 3	11336635	Cloning of a lymphatic peptide/histidine transporter.

Q7G193	ALDO1_ARATH	Aldehyde oxidase 1	9489015	Higher activity of an aldehyde oxidase in the auxin-overproducing superroot1 mutant of Arabidopsis thaliana.

P35609	ACTN2_HUMAN	Alpha-actinin-2	10427098	ZASP: a new Z-band alternatively spliced PDZ-motif protein.

Q8BPI1	KTU_MOUSE	Protein kintoun	19052621	Ktu/PF13 is required for cytoplasmic pre-assembly of axonemal dyneins.

P39958	GDI1_YEAST	Rab GDP-dissociation inhibitor	8157010	GDI1 encodes a GDP dissociation inhibitor that plays an essential role in the yeast secretory pathway.

Q8LGU6	CD27B_ARATH	Cell division cycle protein 27 homolog B	12368267	The Arabidopsis HOBBIT gene encodes a CDC27 homolog that links the plant cell cycle to progression of cell differentiation.

Q92560	BAP1_HUMAN	Ubiquitin carboxyl-terminal hydrolase BAP1	9528852	BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression.

Q9S4P4	SOPA_SALDU	E3 ubiquitin-protein ligase SopA	11207586	The secreted effector protein of Salmonella dublin, SopA, is translocated into eukaryotic cells and influences the induction of enteritis.

Q9VZZ9	DOS_DROME	Protein daughter of sevenless	8681384	Daughter of sevenless is a substrate of the phosphotyrosine phosphatase Corkscrew and functions during sevenless signaling.

O60155	YHY6_SCHPO	Putative prolyl-tRNA synthetase C19C7.06	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P49019	G109B_HUMAN	G-protein coupled receptor 109B	12522134	Molecular identification of high and low affinity receptors for nicotinic acid.

Q39253	CAX1_ARATH	Vacuolar cation/proton exchanger 1	16055687	Functional association of Arabidopsis CAX1 and CAX3 is required for normal growth and ion homeostasis.

Q8LAT0	ATB20_ARATH	Homeobox-leucine zipper protein ATHB-20	12644682	Auxin signaling in Arabidopsis leaf vascular development.

Q08873	SCP1_YEAST	Transgelin	14737190	Protein interaction networks by proteome peptide scanning.

P41738	AHR_RAT	Aryl hydrocarbon receptor	12213388	Role of the aryl hydrocarbon receptor in cell cycle regulation.

Q16760	DGKD_HUMAN	Diacylglycerol kinase delta	12200442	Alternative splicing of the human diacylglycerol kinase delta gene generates two isoforms differing in their expression patterns and in regulatory functions.

Q9VPH2	PRI2_DROME	DNA primase large subunit	11102374	Genetic analysis of the Drosophila DNAprim gene. The function of the 60-kd primase subunit of DNA polymerase opposes the fat facets signaling pathway in the developing eye.

Q15121	PEA15_HUMAN	Astrocytic phosphoprotein PEA-15	9670003	PED/PEA-15 gene controls glucose transport and is overexpressed in type 2 diabetes mellitus.

P38630	RFC1_YEAST	Replication factor C subunit 1	7651383	Characterization of the five replication factor C genes of Saccharomyces cerevisiae.

Q2RBR1	PHT1B_ORYSJ	Phototropin-1B	12068117	Photochemical properties of the flavin mononucleotide-binding domains of the phototropins from Arabidopsis, rice, and Chlamydomonas reinhardtii.

Q02535	ID3_HUMAN	DNA-binding protein inhibitor ID-3	1628620	Mutually exclusive expression of a helix-loop-helix gene and N-myc in human neuroblastomas and in normal development.

P56523	CLR3_SCHPO	Histone deacetylase clr3	17289569	SHREC, an effector complex for heterochromatic transcriptional silencing.

O94585	YQ7D_SCHPO	Meiotically up-regulated protein C1442.13c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P30277	CCNB1_RAT	G2/mitotic-specific cyclin-B1	8123599	Posttranscriptional regulation of cyclin B messenger RNA expression in the regenerating rat liver.

P0AGM9	XANP_ECOLI	Xanthine permease XanP	16096267	Cloning and functional characterization of two bacterial members of the NAT/NCS2 family in Escherichia coli.

P26378	ELAV4_HUMAN	ELAV-like protein 4	1655278	HuD, a paraneoplastic encephalomyelitis antigen, contains RNA-binding domains and is homologous to Elav and Sex-lethal.

Q680Q4	SIZ1_ARATH	E3 SUMO-protein ligase SIZ1	17041025	SIZ1 small ubiquitin-like modifier E3 ligase facilitates basal thermotolerance in Arabidopsis independent of salicylic acid.

Q9QZM3	CLCF1_MOUSE	Cardiotrophin-like cytokine factor 1	10500198	Novel neurotrophin-1/B cell-stimulating factor-3: a cytokine of the IL-6 family.

Q9NR61	DLL4_HUMAN	Delta-like protein 4	10837024	Dll4, a novel Notch ligand expressed in arterial endothelium.

Q8I0P1	SPAST_DROME	Spastin	15562320	Drosophila spastin regulates synaptic microtubule networks and is required for normal motor function.

Q55GH4	GYS_DICDI	Glycogen [starch] synthase	9023987	Isolation and characterization of glycogen synthase in Dictyostelium discoideum.

P55863	SOX3A_XENLA	Transcription factor Sox-3-A	10549281	Regulation of Wnt signaling by Sox proteins: XSox17 alpha/beta and XSox3 physically interact with beta-catenin.

Q59MQ0	MYO5_CANAL	Myosin-5	15470256	Functional characterization of myosin I tail regions in Candida albicans.

Q8INB9	AKT1_DROME	RAC serine/threonine-protein kinase	11872800	Living with lethal PIP3 levels: viability of flies lacking PTEN restored by a PH domain mutation in Akt/PKB.

Q9P7B5	WSS1_SCHPO	DNA damage response protein wss1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P19878	NCF2_HUMAN	Neutrophil cytosol factor 2	1692159	Cloning of a 67-kD neutrophil oxidase factor with similarity to a noncatalytic region of p60c-src.

P83173	HCYA_CHEDE	Hemocyanin A chain	2620501	The relationship between N-terminal sequences and immunological characterization of crustacean hemocyanins.

O00267	SPT5H_HUMAN	Transcription elongation factor SPT5	10075709	Structure and function of the human transcription elongation factor DSIF.

P32344	COX24_YEAST	Mitochondrial mRNA-processing protein COX24	16339141	COX24 codes for a mitochondrial protein required for processing of the COX1 transcript.

Q15393	SF3B3_HUMAN	Splicing factor 3B subunit 3	10490618	Characterization of a protein complex containing spliceosomal proteins saps 49,130,145 and 155.

Q13564	ULA1_HUMAN	NEDD8-activating enzyme E1 regulatory subunit	12694406	ASPP2 inhibits APP-BP1-mediated NEDD8 conjugation to cullin-1 and decreases APP-BP1-induced cell proliferation and neuronal apoptosis.

Q9ZZW7	MBI3_YEAST	Cytochrome b mRNA maturase bI3	9872396	The complete sequence of the mitochondrial genome of Saccharomyces cerevisiae.

Q50754	HDRC_METTM	CoB--CoM heterodisulfide reductase iron-sulfur subunit C	7925445	The heterodisulfide reductase from Methanobacterium thermoautotrophicum contains sequence motifs characteristic of pyridine-nucleotide-dependent thioredoxin reductases.

P08758	ANXA5_HUMAN	Annexin A5	2967495	Characterization of cDNA encoding human placental anticoagulant protein (PP4): homology with the lipocortin family.

Q26622	SHR2_STRPU	Orphan steroid hormone receptor 2	11553912	Differential cellular compartmentalization of the nuclear receptor SpSHR2 splicing variants in early sea urchin embryos.

Q00939	FOXG1_RAT	Forkhead box protein G1	1350202	Telencephalon-restricted expression of BF-1, a new member of the HNF- 3/fork head gene family, in the developing rat brain.

Q9U2Q9	GSK3_CAEEL	Glycogen synthase kinase-3	16289132	DYRK2 and GSK-3 phosphorylate and promote the timely degradation of OMA-1, a key regulator of the oocyte-to-embryo transition in C. elegans.

Q9FKS0	UKL1_ARATH	Uridine kinase-like protein 1, chloroplastic	17143579	Functional characterization of a gene encoding a dual domain for uridine kinase and uracil phosphoribosyltransferase in Arabidopsis thaliana.

O82491	SPT16_ARATH	FACT complex subunit SPT16	15546350	The chromatin remodelling complex FACT associates with actively transcribed regions of the Arabidopsis genome.

Q9XJ36	CLPR2_ARATH	ATP-dependent Clp protease proteolytic subunit-related protein 2, chloroplastic	16461379	Protein profiling of plastoglobules in chloroplasts and chromoplasts. A surprising site for differential accumulation of metabolic enzymes.

P00899	TRPE_YEAST	Anthranilate synthase component 1	6323449	Nucleotide sequence of Saccharomyces cerevisiae genes TRP2 and TRP3 encoding bifunctional anthranilate synthase: indole-3-glycerol phosphate synthase.

Q9VXN9	PGPLE_DROME	Peptidoglycan-recognition protein LE	15538387	Peptidoglycan recognition protein (PGRP)-LE and PGRP-LC act synergistically in Drosophila immunity.

O43463	SUV91_HUMAN	Histone-lysine N-methyltransferase SUV39H1	19218236	Inhibition of SUV39H1 methyltransferase activity by DBC1.

P85025	BKIP_AGKBI	Bradykinin inhibitor peptide	16277978	Identification and functional analysis of a novel bradykinin inhibitory peptide in the venoms of new world crotalinae pit vipers.

P40047	ALDH5_YEAST	Aldehyde dehydrogenase 5, mitochondrial	9473035	Molecular cloning, characterization, and potential roles of cytosolic and mitochondrial aldehyde dehydrogenases in ethanol metabolism in Saccharomyces cerevisiae.

Q08012	DRK_DROME	Protein enhancer of sevenless 2B	9671493	Disabled is a putative adaptor protein that functions during signaling by the sevenless receptor tyrosine kinase.

P11926	DCOR_HUMAN	Ornithine decarboxylase	16548883	Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection.

Q9UW81	NOP1_NEUCR	Opsin-1	12403457	A Fourier transform infrared study of Neurospora rhodopsin: similarities with archaeal rhodopsins.

Q9UER7	DAXX_HUMAN	Death domain-associated protein 6	10698492	EAP1/Daxx interacts with ETS1 and represses transcriptional activation of ETS1 target genes.

P62255	UB2G1_RAT	Ubiquitin-conjugating enzyme E2 G1	10329663	Identification of rabbit reticulocyte E217K as a UBC7 homologue and functional characterization of its core domain loop.

P36146	LAS1_YEAST	Protein LAS1	8582632	LAS1 is an essential nuclear protein involved in cell morphogenesis and cell surface growth.

P12883	MYH7_HUMAN	Myosin-7	15856146	Prevalence of cardiac beta-myosin heavy chain gene mutations in patients with hypertrophic cardiomyopathy.

Q9R0G8	NRK_MOUSE	Nik-related protein kinase	10801798	NESK, a member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and is expressed during the late stages of embryogenesis.

Q12447	PAA1_YEAST	Polyamine N-acetyltransferase 1	15723835	A yeast polyamine acetyltransferase.

Q10168	NSP1_SCHPO	Nucleoporin nsp1	15116432	Identification of genes encoding putative nucleoporins and transport factors in the fission yeast Schizosaccharomyces pombe: a deletion analysis.

Q9CZQ9	BBS5_MOUSE	Bardet-Biedl syndrome 5 protein homolog	15137946	Comparative genomics identifies a flagellar and basal body proteome that includes the BBS5 human disease gene.

Q17802	CPG1_CAEEL	Chondroitin proteoglycan 1	17913784	Cortical granule exocytosis in C. elegans is regulated by cell cycle components including separase.

Q9NZS9	BFAR_HUMAN	Bifunctional apoptosis regulator	10716992	BAR: an apoptosis regulator at the intersection of caspases and Bcl-2 family proteins.

Q66HS7	PDLI3_RAT	PDZ and LIM domain protein 3	9334352	Actinin-associated LIM protein: identification of a domain interaction between PDZ and spectrin-like repeat motifs.

Q24142	HR78_DROME	Nuclear hormone receptor HR78	14599492	Essential roles for the Dhr78 orphan nuclear receptor during molting of the Drosophila tracheal system.

Q24312	EWG_DROME	DNA-binding protein Ewg	8388540	The Drosophila erect wing gene, which is important for both neuronal and muscle development, encodes a protein which is similar to the sea urchin P3A2 DNA binding protein.

Q96CA5	BIRC7_HUMAN	Baculoviral IAP repeat-containing protein 7	11024045	Livin, a novel inhibitor of apoptosis protein family member.

P42345	MTOR_HUMAN	Serine/threonine-protein kinase mTOR	15718470	Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex.

Q01959	SC6A3_HUMAN	Sodium-dependent dopamine transporter	11343649	Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1.

Q07418	PEX19_YEAST	Peroxisomal membrane protein import receptor PEX19	16679311	Pex19p-dependent targeting of Pex17p, a peripheral component of the peroxisomal protein import machinery.

P00797	RENI_HUMAN	Renin	12045255	Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin.

Q92351	PCP1_SCHPO	Spindle pole body protein pcp1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9FUP0	OPR3_ARATH	12-oxophytodienoate reductase 3	10973494	The Arabidopsis male-sterile mutant, opr3, lacks a 12-oxo- phytodienoic acid reductase required for jasmonate synthesis.

Q9ERR1	NDEL1_MOUSE	Nuclear distribution protein nudE-like 1	16107726	Complete loss of Ndel1 results in neuronal migration defects and early embryonic lethality.

Q14393	GAS6_HUMAN	Growth arrest-specific protein 6	7854420	Axl receptor tyrosine kinase stimulated by the vitamin K-dependent protein encoded by growth-arrest-specific gene 6.

Q9SF38	PP222_ARATH	Pentatricopeptide repeat-containing protein At3g09650, chloroplastic	12782738	HCF152, an Arabidopsis RNA binding pentatricopeptide repeat protein involved in the processing of chloroplast psbB-psbT-psbH-petB-petD RNAs.

Q8R1S4	MTSS1_MOUSE	Metastasis suppressor protein 1	12482861	Mouse MIM, a tissue-specific regulator of cytoskeletal dynamics, interacts with ATP-actin monomers through its C-terminal WH2 domain.

Q8R3L0	MMGT2_MOUSE	Membrane magnesium transporter 2	18057121	Identification and characterization of a novel family of membrane magnesium transporters, MMgT1 and MMgT2.

Q9Z1N9	UN13B_MOUSE	Protein unc-13 homolog B	12070347	Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming.

P11163	ASPG2_YEAST	L-asparaginase 2	3042786	Asparaginase II of Saccharomyces cerevisiae. Characterization of the ASP3 gene.

P38865	CTR2_YEAST	Copper transport protein CTR2	7499355	Molecular characterization of a putative Arabidopsis thaliana copper transporter and its yeast homologue.

Q9UL18	AGO1_HUMAN	Protein argonaute-1	18771919	Importance of translation and nonnucleolytic ago proteins for on- target RNA interference.

A6MHQ4	NKAIN_DROME	Sodium/potassium-transporting ATPase subunit beta-1-interacting protein	17606467	A novel family of transmembrane proteins interacting with beta subunits of the Na,K-ATPase.

P27777	HS16A_ORYSJ	16.9 kDa class I heat shock protein 1	19703271	Rice sHsp genes: genomic organization and expression profiling under stress and development.

Q91ZF7	AARD_RAT	Alanine and arginine-rich domain-containing protein	11997109	Molecular cloning and characterization of a novel gene upregulated early during postnatal rat lung development.

P54829	PTN5_HUMAN	Tyrosine-protein phosphatase non-receptor type 5	7490079	Molecular cloning of the human homolog of a striatum-enriched phosphatase (STEP) gene and chromosomal mapping of the human and murine loci.

Q9Z1E1	FLOT1_RAT	Flotillin-1	9858255	Identification of reggie-1 and reggie-2 as plasmamembrane-associated proteins which cocluster with activated GPI-anchored cell adhesion molecules in non-caveolar micropatches in neurons.

P54803	GALC_HUMAN	Galactocerebrosidase	7601472	Structure and organization of the human galactocerebrosidase (GALC) gene.

P04657	CYC1_DROME	Cytochrome c-1	2987802	Characterization of two Drosophila melanogaster cytochrome c genes and their transcripts.

Q9VV73	NXF2_DROME	Nuclear RNA export factor 2	11780633	NXF1/p15 heterodimers are essential for mRNA nuclear export in Drosophila.

O13928	RHO3_SCHPO	GTP-binding protein rho3	12930742	Rho3p regulates cell separation by modulating exocyst function in Schizosaccharomyces pombe.

P14735	IDE_HUMAN	Insulin-degrading enzyme	17613531	Structure of substrate-free human insulin-degrading enzyme (IDE) and biophysical analysis of ATP-induced conformational switch of IDE.

P68696	PRO1A_ACACA	Profilin-1A	2569469	Acanthamoeba actin and profilin can be cross-linked between glutamic acid 364 of actin and lysine 115 of profilin.

Q9HE09	MFH2_SCHPO	Putative ATP-dependent RNA helicase mfh2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q07395	YDL63_YEAST	Uncharacterized protein YDL063C	14562095	Global analysis of protein localization in budding yeast.

P38129	TAF5_YEAST	Transcription initiation factor TFIID subunit 5	9674426	A subset of TAF(II)s are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulation.

Q9VH70	TOPI_DROME	Testis-specific zinc finger protein topi	15084455	Regulation of transcription of meiotic cell cycle and terminal differentiation genes by the testis-specific Zn-finger protein matotopetli.

O54743	FOXF2_MOUSE	Forkhead box protein F2	9676429	Mouse forkhead (winged helix) gene LUN encodes a transactivator that acts in the lung.

P20009	DLL_DROME	Homeotic protein distal-less	1358457	Homeotic genes of the Bithorax complex repress limb development in the abdomen of the Drosophila embryo through the target gene Distal- less.

P22760	AAAD_HUMAN	Arylacetamide deacetylase	19339378	Human arylacetamide deacetylase is a principal enzyme in flutamide hydrolysis.

O74888	YQE4_SCHPO	Uncharacterized membrane protein C576.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UT60	YKJ6_SCHPO	Uncharacterized oxidoreductase C513.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P34708	TRA1_CAEEL	Sex-determining transformer protein 1	11250902	The TRA-1 transcription factor binds TRA-2 to regulate sexual fates in Caenorhabditis elegans.

Q9CAG3	LOX6_ARATH	Lipoxygenase 6, choloroplastic	18949503	Diversity of the enzymatic activity in the lipoxygenase gene family of Arabidopsis thaliana.

O76879	CCCP_DROME	Circadian clock-controlled protein	2517256	Expression of a Drosophila mRNA is under circadian clock control during pupation.

P09912	IFI6_HUMAN	Interferon alpha-inducible protein 6	3017706	Characterization of a human gene inducible by alpha- and beta- interferons and its expression in mouse cells.

Q9EQB9	ZN287_MOUSE	Zinc finger protein 287	11093124	Identification and characterization of SKAT-2, a novel Th2-specific zinc finger gene.

Q02197	NAA35_YEAST	N-alpha-acetyltransferase, 35 NatC auxiliary subunit	14562095	Global analysis of protein localization in budding yeast.

P20305	GELS_PIG	Gelsolin	3023087	Preparation and characterization of pig plasma and platelet gelsolins.

O94398	RM17_SCHPO	60S ribosomal protein L17, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q15633	TRBP2_HUMAN	RISC-loading complex subunit TARBP2	17452327	Human TRBP and PACT directly interact with each other and associate with dicer to facilitate the production of small interfering RNA.

Q99877	H2B1N_HUMAN	Histone H2B type 1-N	9439656	The human histone gene cluster at the D6S105 locus.

Q16864	VATF_HUMAN	V-type proton ATPase subunit F	8581736	Cloning, sequencing and expression of a novel cDNA encoding human vacuolar ATPase (14-kDa subunit).

Q03103	ERO1_YEAST	Endoplasmic oxidoreductin-1	9659914	Ero1p: a novel and ubiquitous protein with an essential role in oxidative protein folding in the endoplasmic reticulum.

O14019	HAL4_SCHPO	Serine/threonine-protein kinase hal4	16164595	A novel pathway determining multidrug sensitivity in Schizosaccharomyces pombe.

P08621	RU17_HUMAN	U1 small nuclear ribonucleoprotein 70 kDa	3028775	Cloning of the human cDNA for the U1 RNA-associated 70K protein.

Q3E764	TMA7_YEAST	Translation machinery-associated protein 7	16702403	Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes.

O74989	YJZC_SCHPO	Uncharacterized protein C338.12	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O60499	STX10_HUMAN	Syntaxin-10	9446797	Syntaxin 10: a member of the syntaxin family localized to the trans- Golgi network.

O55028	BCKD_MOUSE	[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial	9611264	Murine branched chain alpha ketoacid dehydrogenase kinase; cDNA cloning, tissue distribution, and temporal expression during embryonic development.

Q9WVI4	GCYA2_RAT	Guanylate cyclase soluble subunit alpha-2	11121588	Cloning and functional expression of the rat alpha(2) subunit of soluble guanylyl cyclase.

Q9ATB4	TAD2B_ARATH	Transcriptional adapter ADA2b	12615937	Disruption mutations of ADA2b and GCN5 transcriptional adaptor genes dramatically affect Arabidopsis growth, development, and gene expression.

Q9JMH9	MY18A_MOUSE	Myosin-XVIIIa	10733906	Isolation of a novel PDZ-containing myosin from hematopoietic supportive bone marrow stromal cell lines.

Q9NVA2	SEP11_HUMAN	Septin-11	15485874	Biochemical and cell biological analyses of a mammalian septin complex, Sept7/9b/11.

P35908	K22E_HUMAN	Keratin, type II cytoskeletal 2 epidermal	12598329	Expression of keratin K2e in cutaneous and oral lesions: association with keratinocyte activation, proliferation, and keratinization.

P45973	CBX5_HUMAN	Chromobox protein homolog 5	19666599	Human BAHD1 promotes heterochromatic gene silencing.

Q9BZ76	CNTP3_HUMAN	Contactin-associated protein-like 3	12093160	Caspr3 and Caspr4, two novel members of the Caspr family are expressed in the nervous system and interact with PDZ domains.

P55854	SUMO3_HUMAN	Small ubiquitin-related modifier 3	9119407	SMT3A, a human homologue of the S. cerevisiae SMT3 gene, maps to chromosome 21qter and defines a novel gene family.

P70539	ACV1C_RAT	Activin receptor type-1C	15196700	Activin isoforms signal through type I receptor serine/threonine kinase ALK7.

Q9M0V3	DDB1A_ARATH	DNA damage-binding protein 1a	16844902	Arabidopsis CULLIN4 forms an E3 ubiquitin ligase with RBX1 and the CDD complex in mediating light control of development.

P15879	ARC3_CBDP	Mono-ADP-ribosyltransferase C3	15809419	Molecular recognition of an ADP-ribosylating Clostridium botulinum C3 exoenzyme by RalA GTPase.

Q9FDX8	HD1_ORYSJ	Zinc finger protein HD1	12700762	Adaptation of photoperiodic control pathways produces short-day flowering in rice.

O74810	UBC1_SCHPO	Ubiquitin-conjugating enzyme E2 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P57094	AXN1_DANRE	Axin-1	17681137	A beta-catenin-independent dorsalization pathway activated by Axin/JNK signaling and antagonized by aida.

P29476	NOS1_RAT	Nitric oxide synthase, brain	10221915	Unexpected modes of PDZ domain scaffolding revealed by structure of nNOS-syntrophin complex.

Q9SYF0	GLIP2_ARATH	GDSL esterase/lipase 2	19146828	Arabidopsis GDSL lipase 2 plays a role in pathogen defense via negative regulation of auxin signaling.

Q500Y9	NADHK_ARATH	NADH kinase	15347288	Identification, molecular cloning and functional characterization of a novel NADH kinase from Arabidopsis thaliana (thale cress).

P81913	OR24A_DROME	Putative odorant receptor 24a	10069338	A novel family of divergent seven-transmembrane proteins: candidate odorant receptors in Drosophila.

O64425	RMA1_ARATH	E3 ubiquitin-protein ligase RMA1	19234086	Drought stress-induced Rma1H1, a RING membrane-anchor E3 ubiquitin ligase homolog, regulates aquaporin levels via ubiquitination in transgenic Arabidopsis plants.

O14090	YER7_SCHPO	Uncharacterized protein C2F3.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9DCM2	GSTK1_MOUSE	Glutathione S-transferase kappa 1	12720545	Biochemical and genetic characterization of a murine class Kappa glutathione S-transferase.

P18064	GPA1_ARATH	Guanine nucleotide-binding protein alpha-1 subunit	19135895	Two novel GPCR-type G proteins are abscisic acid receptors in Arabidopsis.

Q12040	YO283_YEAST	Probable phosphoglycerate mutase YOR283W	14562095	Global analysis of protein localization in budding yeast.

Q92922	SMRC1_HUMAN	SWI/SNF complex subunit SMARCC1	8804307	Diversity and specialization of mammalian SWI/SNF complexes.

P24871	CG24_YEAST	G2/mitotic-specific cyclin-4	1427070	Cyclin-B homologs in Saccharomyces cerevisiae function in S phase and in G2.

P14020	DPM1_YEAST	Dolichol-phosphate mannosyltransferase	3053713	Cloning and sequencing of the yeast gene for dolichol phosphate mannose synthase, an essential protein.

O14896	IRF6_HUMAN	Interferon regulatory factor 6	18212048	Interferon regulatory factor 6 promotes cell cycle arrest and is regulated by the proteasome in a cell cycle-dependent manner.

Q04377	LCD1_YEAST	DNA damage checkpoint protein LCD1	10950868	The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast.

P39741	RL35_YEAST	60S ribosomal protein L35	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q9Z2F2	OASL2_MOUSE	54 kDa 2'-5'-oligoadenylate synthase-like protein 2	10395668	M1204, a novel 2',5' oligoadenylate synthetase with a ubiquitin-like extension, is induced during maturation of murine dendritic cells.

Q13402	MYO7A_HUMAN	Myosin-VIIa	7870171	Defective myosin VIIA gene responsible for Usher syndrome type 1B.

P56556	NDUA6_HUMAN	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

P84644	CIRF_CHAPA	Circulin-F	10691702	New circulin macrocyclic polypeptides from Chassalia parvifolia.

Q9SZ63	NUD14_ARATH	Nudix hydrolase 14, chloroplastic	18815383	Molecular characterization of organelle-type Nudix hydrolases in Arabidopsis.

Q9P2D7	DYH1_HUMAN	Dynein heavy chain 1, axonemal	8812413	Multiple mouse chromosomal loci for dynein-based motility.

Q0JKD0	GLT1_ORYSJ	Glutamate synthase 1 [NADH]	20213442	Reverse genetics approach to characterize a function of NADH- glutamate synthase1 in rice plants.

Q14112	NID2_HUMAN	Nidogen-2	11956183	The type XIII collagen ectodomain is a 150-nm rod and capable of binding to fibronectin, nidogen-2, perlecan, and heparin.

O22607	MSI4_ARATH	WD-40 repeat-containing protein MSI4	9872415	AtMSI4 and RbAp48 WD-40 repeat proteins bind metal ions.

Q16873	LTC4S_HUMAN	Leukotriene C4 synthase	7599836	Purification of human lung leukotriene C4 synthase and preparation of a polyclonal antibody.

O80796	IM30_ARATH	Probable membrane-associated 30 kDa protein, chloroplastic	12766230	Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.

Q12118	SGT2_YEAST	Small glutamine-rich tetratricopeptide repeat-containing protein 2	17441508	SGT2 and MDY2 interact with molecular chaperone YDJ1 in Saccharomyces cerevisiae.

O15444	CCL25_HUMAN	C-C motif chemokine 25	9285413	TECK: a novel CC chemokine specifically expressed by thymic dendritic cells and potentially involved in T cell development.

Q8GYN5	RIN4_ARATH	RPM1-interacting protein 4	12581527	Arabidopsis RIN4 is a target of the type III virulence effector AvrRpt2 and modulates RPS2-mediated resistance.

P78383	S35B1_HUMAN	Solute carrier family 35 member B1	9010752	Molecular cloning and characterization of a novel isoform of the human UDP-galactose transporter, and of related complementary DNAs belonging to the nucleotide-sugar transporter gene family.

O94266	THI22_SCHPO	Putative hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q13685	AAMP_HUMAN	Angio-associated migratory cell protein	7743515	Identification of a new immunoglobulin superfamily protein expressed in blood vessels with a heparin-binding consensus sequence.

Q9Z2J4	NEXN_RAT	Nexilin	9832551	Nexilin: a novel actin filament-binding protein localized at cell- matrix adherens junction.

Q8CDG1	PIWL2_MOUSE	Piwi-like protein 2	17446352	Developmentally regulated piRNA clusters implicate MILI in transposon control.

P33201	MRT4_YEAST	mRNA turnover protein 4	11583614	Composition and functional characterization of yeast 66S ribosome assembly intermediates.

P21135	SECU_SCHPO	Securin	8632802	Cut2 proteolysis required for sister-chromatid seperation in fission yeast.

Q8GXR9	DHNA_ARATH	Probable NADH dehydrogenase, chloroplastic/mitochondrial	16461379	Protein profiling of plastoglobules in chloroplasts and chromoplasts. A surprising site for differential accumulation of metabolic enzymes.

Q7T2V3	M3K10_XENLA	Mitogen-activated protein kinase kinase kinase 10	18021256	A ubiquitin-conjugating enzyme, ube2d3.2, regulates xMLK2 and pronephros formation in Xenopus.

Q570C0	TIR1_ARATH	Protein TRANSPORT INHIBITOR RESPONSE 1	12215511	Role of the Arabidopsis RING-H2 protein RBX1 in RUB modification and SCF function.

P38803	IPI1_YEAST	Pre-rRNA-processing protein IPI1	14562095	Global analysis of protein localization in budding yeast.

Q06330	SUH_HUMAN	Recombining binding protein suppressor of hairless	8406481	Human Jk recombination signal binding protein gene (IGKJRB): comparison with its mouse homologue.

O43933	PEX1_HUMAN	Peroxisome biogenesis factor 1	11439091	Phenotype-genotype relationships in peroxisome biogenesis disorders of PEX1-defective complementation group 1 are defined by Pex1p-Pex6p interaction.

P53732	RT12_YEAST	37S ribosomal protein S12, mitochondrial	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

P05107	ITB2_HUMAN	Integrin beta-2	1683838	The gene organisation of the human beta 2 integrin subunit (CD18).

Q9P278	FNIP2_HUMAN	Folliculin-interacting protein 2	18403135	Identification and characterization of a novel folliculin-interacting protein FNIP2.

O15123	ANGP2_HUMAN	Angiopoietin-2	9204896	Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis.

P87324	DPOD2_SCHPO	DNA polymerase subunit delta-2	8887553	The fission yeast Cdc1 protein, a homologue of the small subunit of DNA polymerase delta, binds to Pol3 and Cdc27.

P70396	DLX5_MOUSE	Homeobox protein DLX-5	15383550	Bone morphogenetic protein-2-induced alkaline phosphatase expression is stimulated by Dlx5 and repressed by Msx2.

Q03825	MSS11_YEAST	Transcription activator MSS11	9832522	Regulators of pseudohyphal differentiation in Saccharomyces cerevisiae identified through multicopy suppressor analysis in ammonium permease mutant strains.

Q9C0G6	DYH6_HUMAN	Dynein heavy chain 6, axonemal	8812413	Multiple mouse chromosomal loci for dynein-based motility.

Q62951	DPYL4_RAT	Dihydropyrimidinase-related protein 4	8815901	A family of rat CRMP genes is differentially expressed in the nervous system.

Q9H9Z2	LN28A_HUMAN	Protein lin-28 homolog A	19703396	TUT4 in concert with Lin28 suppresses MicroRNA biogenesis through pre-microRNA uridylation.

Q8IC32	Y7014_PLAF7	Leucine-rich repeat and coiled-coil domain-containing protein PF07_0014	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

P97837	DLGP2_RAT	Disks large-associated protein 2	9115257	SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density.

Q9LJL3	PREP1_ARATH	Presequence protease 1, chloroplastic/mitochondrial	12138166	Isolation and identification of a novel mitochondrial metalloprotease (PreP) that degrades targeting presequences in plants.

P02708	ACHA_HUMAN	Acetylcholine receptor subunit alpha	6688857	Cloning and sequence analysis of calf cDNA and human genomic DNA encoding alpha-subunit precursor of muscle acetylcholine receptor.

Q9LX08	ANXD6_ARATH	Annexin D6	16531057	Expression profiling of the Arabidopsis annexin gene family during germination, de-etiolation and abiotic stress.

P70323	TBX1_MOUSE	T-box transcription factor TBX1	11242049	Tbx1 haploinsufficiency in the DiGeorge syndrome region causes aortic arch defects in mice.

P40339	RFC4_YEAST	Replication factor C subunit 4	11389843	Identification of RFC(Ctf18p, Ctf8p, Dcc1p): an alternative RFC complex required for sister chromatid cohesion in S. cerevisiae.

P34546	VATL2_CAEEL	V-type proton ATPase 16 kDa proteolipid subunit 2/3	9712884	Multiple genes for vacuolar-type ATPase proteolipids in Caenorhabditis elegans: a new gene, vha-3, has a distinct cell- specific distribution.

P34314	TLK1_CAEEL	Serine/threonine-protein kinase tousled-like 1	14614817	The C. elegans Tousled-like kinase (TLK-1) has an essential role in transcription.

P22091	TAL1_MOUSE	T-cell acute lymphocytic leukemia protein 1 homolog	9391090	The LIM-domain binding protein Ldb1 and its partner LMO2 act as negative regulators of erythroid differentiation.

O55159	EPCAM_RAT	Epithelial cell adhesion molecule	10327052	Metastasis-association of the rat ortholog of the human epithelial glycoprotein antigen EGP314.

P53877	IPI3_YEAST	Pre-rRNA-processing protein IPI3	15528184	Rea1, a dynein-related nuclear AAA-ATPase, is involved in late rRNA processing and nuclear export of 60 S subunits.

Q8W5B1	VRN2_ARATH	Polycomb group protein VERNALIZATION 2	11719192	The VERNALIZATION2 (VRN2) gene mediates the epigenetic regulation of vernalization in Arabidopsis.

P61081	UBC12_HUMAN	NEDD8-conjugating enzyme Ubc12	15361859	A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8.

P22211	NPR1_YEAST	Nitrogen permease reactivator protein	11500493	The Npr1 kinase controls biosynthetic and endocytic sorting of the yeast Gap1 permease.

P43563	MOB2_YEAST	CBK1 kinase activator protein MOB2	12196508	The Saccharomyces cerevisiae Mob2p-Cbk1p kinase complex promotes polarized growth and acts with the mitotic exit network to facilitate daughter cell-specific localization of Ace2p transcription factor.

Q9P7L1	YOSC_SCHPO	Thioredoxin domain-containing protein C21C3.12c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q64375	SC65_RAT	Synaptonemal complex protein SC65	1363622	Isolation and characterization of a cDNA encoding a synaptonemal complex protein.

P26998	CRBB3_HUMAN	Beta-crystallin B3	8999933	Sequence analysis of betaA3, betaB3, and betaA4 crystallins completes the identification of the major proteins in young human lens.

Q07799	YL007_YEAST	Uncharacterized protein YLL007C	14562095	Global analysis of protein localization in budding yeast.

O00560	SDCB1_HUMAN	Syntenin-1	9883737	PDZ proteins bind, cluster, and synaptically colocalize with Eph receptors and their ephrin ligands.

P33753	TRM2_YEAST	tRNA (uracil-5-)-methyltransferase	10864043	Identification of the TRM2 gene encoding the tRNA(m5U54)methyltransferase of Saccharomyces cerevisiae.

P04180	LCAT_HUMAN	Phosphatidylcholine-sterol acyltransferase	3458198	Cloning and expression of human lecithin-cholesterol acyltransferase cDNA.

O13725	MU182_SCHPO	Meiotically up-regulated gene 182 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P82873	TO202_ARATH	Mitochondrial import receptor subunit TOM20-2	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

O59753	RAD14_SCHPO	DNA repair protein rad14	11408483	Binding and repair of mismatched DNA mediated by Rhp14, the fission yeast homologue of human XPA.

Q01167	FOXK2_HUMAN	Forkhead box protein K2	1909027	Cloning of a cellular factor, interleukin binding factor, that binds to NFAT-like motifs in the human immunodeficiency virus long terminal repeat.

P77570	ANMK_ECOLI	Anhydro-N-acetylmuramic acid kinase	15901686	Recycling of the anhydro-N-acetylmuramic acid derived from cell wall murein involves a two-step conversion to N-acetylglucosamine- phosphate.

Q43125	CRY1_ARATH	Cryptochrome-1	9651577	The CRY1 blue light photoreceptor of Arabidopsis interacts with phytochrome A in vitro.

P60879	SNP25_MOUSE	Synaptosomal-associated protein 25	16672379	CytLEK1 is a regulator of plasma membrane recycling through its interaction with SNAP-25.

P36421	SYYC_YEAST	Tyrosyl-tRNA synthetase, cytoplasmic	11359929	Role of nuclear pools of aminoacyl-tRNA synthetases in tRNA nuclear export.

Q03860	TVP15_YEAST	Golgi apparatus membrane protein TVP15	16107716	Immunoisolaton of the yeast Golgi subcompartments and characterization of a novel membrane protein, Svp26, discovered in the Sed5-containing compartments.

P28872	CARP1_CANAL	Candidapepsin-1	8407785	Three distinct secreted aspartyl proteinases in Candida albicans.

Q9UQ84	EXO1_HUMAN	Exonuclease 1	14676842	Characterization of human exonuclease 1 in complex with mismatch repair proteins, subcellular localization and association with PCNA.

P53369	8ODP_RAT	7,8-dihydro-8-oxoguanine triphosphatase	7586133	cDNA and genomic sequences for rat 8-oxo-dGTPase that prevents occurrence of spontaneous mutations due to oxidation of guanine nucleotides.

Q9LV03	GLUT1_ARATH	Glutamate synthase 1 [NADH]	11844111	Arabidopsis glt1-T mutant defines a role for NADH-GOGAT in the non- photorespiratory ammonium assimilatory pathway.

P39547	UIP3_YEAST	ULP1-interacting protein 3	11056382	Yeast Ulp1, an Smt3-specific protease, associates with nucleoporins.

Q92963	RIT1_HUMAN	GTP-binding protein Rit1	8918462	RIC, a calmodulin-binding Ras-like GTPase.

Q42525	HXK1_ARATH	Hexokinase-1	12690200	Role of the Arabidopsis glucose sensor HXK1 in nutrient, light, and hormonal signaling.

Q03173	ENAH_MOUSE	Protein enabled homolog	10069337	Mena is required for neurulation and commissure formation.

P08243	ASNS_HUMAN	Asparagine synthetase [glutamine-hydrolyzing]	2569668	Organization and expression of the cell cycle gene, ts11, that encodes asparagine synthetase.

Q7TPV4	MBB1A_MOUSE	Myb-binding protein 1A	14744933	Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK.

Q8WYQ5	DGCR8_HUMAN	Microprocessor complex subunit DGCR8	15531877	The microprocessor complex mediates the genesis of microRNAs.

P99024	TBB5_MOUSE	Tubulin beta-5 chain	3782288	The mammalian beta-tubulin repertoire: hematopoietic expression of a novel, heterologous beta-tubulin isotype.

P21218	PORB_ARATH	Protochlorophyllide reductase B, chloroplastic	12766230	Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.

Q8NC01	CLC1A_HUMAN	C-type lectin domain family 1 member A	10671229	Molecular characterization of two novel C-type lectin-like receptors, one of which is selectively expressed in human dendritic cells.

Q04782	ERG7_CANAL	Lanosterol synthase	8486282	Sequence of the Candida albicans erg7 gene.

Q9P3W6	YLI2_SCHPO	Uncharacterized protein C458.02c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8BL03	MCATL_MOUSE	Mitochondrial carnitine/acylcarnitine carrier protein CACL	12882971	A novel mitochondrial carnitine-acylcarnitine translocase induced by partial hepatectomy and fasting.

Q91898	HESXB_XENLA	Homeobox expressed in ES cells 1-B	18297730	The LIM-domain protein zyxin binds the homeodomain factor Xanf1/Hesx1 and modulates its activity in the anterior neural plate of Xenopus laevis embryo.

Q4LDG0	S27A5_MOUSE	Bile acyl-CoA synthetase	9671728	A family of fatty acid transporters conserved from mycobacterium to man.

P32559	MSS1_YEAST	tRNA modification GTPase MSS1, mitochondrial	15509579	Mitochondria-specific RNA-modifying enzymes responsible for the biosynthesis of the wobble base in mitochondrial tRNAs. Implications for the molecular pathogenesis of human mitochondrial diseases.

O59746	YN2B_SCHPO	Uncharacterized transcriptional regulatory protein C530.11c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P39685	PO152_YEAST	Nucleoporin POM152	9988776	Topology and functional domains of the yeast pore membrane protein Pom152p.

O35437	TCF21_MOUSE	Transcription factor 21	9545526	Cloning of capsulin, a basic helix-loop-helix factor expressed in progenitor cells of the pericardium and the coronary arteries.

P62495	ERF1_HUMAN	Eukaryotic peptide chain release factor subunit 1	10413110	Human release factor eRF1: structural organisation of the unique functional gene on chromosome 5 and of the three processed pseudogenes.

Q9NGX9	CP302_DROME	Cytochrome P450 302a1, mitochondrial	14610274	Shade is the Drosophila P450 enzyme that mediates the hydroxylation of ecdysone to the steroid insect molting hormone 20- hydroxyecdysone.

Q8BSK8	KS6B1_MOUSE	Ribosomal protein S6 kinase beta-1	11493700	p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD.

P39015	STM1_YEAST	Suppressor protein STM1	11514626	The proteasomal substrate Stm1 participates in apoptosis-like cell death in yeast.

P01876	IGHA1_HUMAN	Ig alpha-1 chain C region	107164	Primary structure of a human IgA1 immunoglobulin. IV. Streptococcal IgA1 protease, digestion, Fab and Fc fragments, and the complete amino acid sequence of the alpha 1 heavy chain.

Q09161	NCBP1_HUMAN	Nuclear cap-binding protein subunit 1	15361857	eIF4G is required for the pioneer round of translation in mammalian cells.

Q9C000	NALP1_HUMAN	NACHT, LRR and PYD domains-containing protein 1	15212762	Expression of NALP1 in cerebellar granule neurons stimulates apoptosis.

Q92839	HAS1_HUMAN	Hyaluronan synthase 1	8798544	Functional cloning of the cDNA for a human hyaluronan synthase.

O74844	FTA7_SCHPO	Kinetochore protein fta7	16079914	Molecular analysis of kinetochore architecture in fission yeast.

Q16654	PDK4_HUMAN	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial	18658136	Pyruvate dehydrogenase kinase-4 structures reveal a metastable open conformation fostering robust core-free basal activity.

Q682V0	XRCC4_ARATH	DNA repair protein XRCC4	11029705	Arabidopsis DNA ligase IV is induced by gamma-irradiation and interacts with an Arabidopsis homologue of the double strand break repair protein XRCC4.

Q8CG65	SSPO_MOUSE	SCO-spondin	12909363	Mouse SCO-spondin, a gene of the thrombospondin type 1 repeat (TSR) superfamily expressed in the brain.

Q9H611	PIF1_HUMAN	ATP-dependent DNA helicase PIF1	16522649	The human Pif1 helicase, a potential Escherichia coli RecD homologue, inhibits telomerase activity.

P50076	ALG10_YEAST	Alpha-1,2 glucosyltransferase ALG10	9597543	The ALG10 locus of Saccharomyces cerevisiae encodes the alpha-1,2 glucosyltransferase of the endoplasmic reticulum: the terminal glucose of the lipid-linked oligosaccharide is required for efficient N-linked glycosylation.

P10711	TCEA1_MOUSE	Transcription elongation factor A protein 1	12761297	Identification of a novel tissue-specific transcriptional activator FESTA as a protein that interacts with the transcription elongation factor S-II.

Q9YGC3	CXR4A_XENLA	C-X-C chemokine receptor type 4-A	17239342	SDF-1 alpha regulates mesendodermal cell migration during frog gastrulation.

Q6P6J4	ALKB2_MOUSE	Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2	16174769	Repair of methylation damage in DNA and RNA by mammalian AlkB homologues.

Q9UPZ9	ICK_HUMAN	Serine/threonine-protein kinase ICK	10699974	Intestinal cell kinase (ICK) localizes to the crypt region and requires a dual phosphorylation site found in map kinases.

Q6X893	CTL1_MOUSE	Choline transporter-like protein 1	15474312	Identification and expression of a mouse muscle-specific CTL1 gene.

Q9LRR7	NCED3_ARATH	9-cis-epoxycarotenoid dioxygenase NCED3, chloroplastic	11532178	Regulation of drought tolerance by gene manipulation of 9-cis- epoxycarotenoid dioxygenase, a key enzyme in abscisic acid biosynthesis in Arabidopsis.

P38839	SPL2_YEAST	Putative cyclin-dependent kinase inhibitor SPL2	9475719	An essential function of a phosphoinositide-specific phospholipase C is relieved by inhibition of a cyclin-dependent protein kinase in the yeast Saccharomyces cerevisiae.

P70290	EM55_MOUSE	55 kDa erythrocyte membrane protein	16829577	Whirlin complexes with p55 at the stereocilia tip during hair cell development.

Q9C7S0	BZI60_ARATH	bZIP transcription factor 60	15781873	An Arabidopsis transcription factor, AtbZIP60, regulates the endoplasmic reticulum stress response in a manner unique to plants.

Q04304	YMY0_YEAST	UPF0659 protein YMR090W	14562095	Global analysis of protein localization in budding yeast.

Q8LEA8	EID1_ARATH	Phytochrome A-associated F-box protein	12795696	Protein interaction analysis of SCF ubiquitin E3 ligase subunits from Arabidopsis.

P53632	PAP2_YEAST	Poly(A) RNA polymerase protein 2	12062100	Cid13 is a cytoplasmic poly(A) polymerase that regulates ribonucleotide reductase mRNA.

P33241	LSP1_HUMAN	Lymphocyte-specific protein 1	2174784	Molecular cloning and characterization of WP34, a phosphorylated human lymphocyte differentiation and activation antigen.

P82349	SGCB_MOUSE	Beta-sarcoglycan	10448073	Developmental expression of sarcoglycan gene products in cultured myocytes.

O54833	CSK22_MOUSE	Casein kinase II subunit alpha'	9503019	Murine protein kinase CK2 alpha': cDNA and genomic cloning and chromosomal mapping.

P22033	MUTA_HUMAN	Methylmalonyl-CoA mutase, mitochondrial	2567699	Cloning of full-length methylmalonyl-CoA mutase from a cDNA library using the polymerase chain reaction.

Q9P6M1	GST3_SCHPO	Glutathione S-transferase 3	12151111	Characterization, expression and regulation of a third gene encoding glutathione S-transferase from the fission yeast.

P35197	GCS1_YEAST	ADP-ribosylation factor GTPase-activating protein GCS1	9927415	Retrograde transport from the yeast Golgi is mediated by two ARF GAP proteins with overlapping function.

P86096	NXL2_MICSU	Long neurotoxin MS2	18384102	Proteomic analysis of the venom from the fish eating coral snake Micrurus surinamensis: novel toxins, their function and phylogeny.

P70096	KIF2C_CRIGR	Kinesin-like protein KIF2C	19543227	TIP150 interacts with and targets MCAK at the microtubule plus ends.

Q9ZR12	GRH1_ARATH	GRR1-like protein 1	16627744	A plant miRNA contributes to antibacterial resistance by repressing auxin signaling.

P87054	MUG15_SCHPO	Meiotically up-regulated gene 15 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q6UX65	DRAM2_HUMAN	DNA damage-regulated autophagy modulator protein 2	19895784	Reduced expression of DRAM2/TMEM77 in tumor cells interferes with cell death.

P25847	MSH2_YEAST	DNA mismatch repair protein MSH2	10066781	Saccharomyces cerevisiae MSH2/6 complex interacts with Holliday junctions and facilitates their cleavage by phage resolution enzymes.

Q9H1A4	APC1_HUMAN	Anaphase-promoting complex subunit 1	18485873	Mechanism of ubiquitin-chain formation by the human anaphase- promoting complex.

P53192	GET1_YEAST	Golgi to ER traffic protein 1	18724936	The GET complex mediates insertion of tail-anchored proteins into the ER membrane.

Q9QXM1	JMY_MOUSE	Junction-mediating and -regulatory protein	19287377	p53-cofactor JMY is a multifunctional actin nucleation factor.

Q21443	LMN1_CAEEL	Lamin-1	12490171	Transmission electron microscope studies of the nuclear envelope in Caenorhabditis elegans embryos.

Q9LPL4	SKP2A_ARATH	F-box protein SKP2A	19704565	SKP2A protein, an F-box that regulates cell division, is degraded via the ubiquitin pathway.

Q9HAZ2	PRD16_HUMAN	PR domain zinc finger protein 16	19049980	SKI and MEL1 cooperate to inhibit transforming growth factor-beta signal in gastric cancer cells.

Q13219	PAPP1_HUMAN	Pappalysin-1	10077652	The insulin-like growth factor (IGF)-dependent IGF binding protein-4 protease secreted by human fibroblasts is pregnancy-associated plasma protein-A.

Q9W0P8	MED14_DROME	Mediator of RNA polymerase II transcription subunit 14	11259581	Drosophila Mediator complex is broadly utilized by diverse gene- specific transcription factors at different types of core promoters.

O54839	EOMES_MOUSE	Eomesodermin homolog	14605368	Control of effector CD8+ T cell function by the transcription factor Eomesodermin.

P27169	PON1_HUMAN	Serum paraoxonase/arylesterase 1	15098021	Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes.

Q15024	EXOS7_HUMAN	Exosome complex exonuclease RRP42	11812149	Protein-protein interactions of hCsl4p with other human exosome subunits.

P47755	CAZA2_HUMAN	F-actin-capping protein subunit alpha-2	9331217	Vertebrates have conserved capping protein alpha isoforms with specific expression patterns.

P04079	GUAA_ECOLI	GMP synthase [glutamine-hydrolyzing]	9890911	N2-hydroxyguanosine 5'-monophosphate is a time-dependent inhibitor of Escherichia coli guanosine monophosphate synthetase.

Q8TAQ2	SMRC2_HUMAN	SWI/SNF complex subunit SMARCC2	12917342	BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation.

P70445	4EBP2_MOUSE	Eukaryotic translation initiation factor 4E-binding protein 2	8939971	Control of the translational regulators PHAS-I and PHAS-II by insulin and cAMP in 3T3-L1 adipocytes.

Q8IS21	GEFB_DICDI	Ras guanine nucleotide exchange factor B	12854977	Parasexual genetics of Dictyostelium gene disruptions: identification of a ras pathway using diploids.

Q9VDH4	TOTB_DROME	Protein Turandot B	11409894	A family of Turandot-related genes in the humoral stress response of Drosophila.

Q10665	MES3_CAEEL	Polycomb protein mes-3	15380065	The MES-2/MES-3/MES-6 complex and regulation of histone H3 methylation in C. elegans.

Q8LGI2	SCPDH_ARATH	Probable mitochondrial saccharopine dehydrogenase At5g39410	15276431	The hydrophobic proteome of mitochondrial membranes from Arabidopsis cell suspensions.

A8WIP6	CDK20_DANRE	Cell division protein kinase 20	20159594	Broad-minded links cell cycle-related kinase to cilia assembly and hedgehog signal transduction.

Q9UBB5	MBD2_HUMAN	Methyl-CpG-binding domain protein 2	10441743	Genomic structure and chromosomal mapping of the murine and human mbd1, mbd2, mbd3, and mbd4 genes.

Q7BVH7	SSEB_SALTY	Secreted effector protein sseB	15256549	The SPI2-encoded SseA chaperone has discrete domains required for SseB stabilization and export, and binds within the C-terminus of SseB and SseD.

Q811R2	PRGC2_RAT	Peroxisome proliferator-activated receptor gamma coactivator 1-beta	12807885	PGC-1beta in the regulation of hepatic glucose and energy metabolism.

Q9H2T7	RBP17_HUMAN	Ran-binding protein 17	11024021	Identification of two novel RanGTP-binding proteins belonging to the importin beta superfamily.

Q03067	SGF11_YEAST	SAGA-associated factor 11	15657442	The deubiquitylation activity of Ubp8 is dependent upon Sgf11 and its association with the SAGA complex.

P25873	RK15_ARATH	50S ribosomal protein L15, chloroplastic	1581570	Characterization of rps17, rp19 and rpl15: three nucleus-encoded plastid ribosomal protein genes.

Q9UNS1	TIM_HUMAN	Protein timeless homolog	9891984	Identification of the mammalian homologues of the Drosophila timeless gene, Timeless1.

P48200	IREB2_HUMAN	Iron-responsive element-binding protein 2	19762597	An E3 ligase possessing an iron responsive hemerythrin domain is a regulator of iron homeostasis.

Q99828	CIB1_HUMAN	Calcium and integrin-binding protein 1	9030514	Identification of a novel calcium-binding protein that interacts with the integrin alphaIIb cytoplasmic domain.

Q8TCJ0	FBX25_HUMAN	F-box only protein 25	10531035	Identification of a family of human F-box proteins.

Q12513	TMA17_YEAST	Translation machinery-associated protein 17	16702403	Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes.

P82251	BAT1_HUMAN	B(0,+)-type amino acid transporter 1	11318953	Human cystinuria-related transporter: localization and functional characterization.

P22090	RS4Y1_HUMAN	40S ribosomal protein S4, Y isoform 1	2124517	Homologous ribosomal protein genes on the human X and Y chromosomes: escape from X inactivation and possible implications for Turner syndrome.

P09032	EI2BG_YEAST	Translation initiation factor eIF-2B subunit gamma	9472020	eIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine-nucleotide exchange.

Q9JLU4	SHAN3_RAT	SH3 and multiple ankyrin repeat domains protein 3	16522626	ProSAP-interacting protein 1 (ProSAPiP1), a novel protein of the postsynaptic density that links the spine-associated Rap-Gap (SPAR) to the scaffolding protein ProSAP2/Shank3.

Q96JB2	COG3_HUMAN	Conserved oligomeric Golgi complex subunit 3	11292827	Identification of a human ortholog of Sec34p as a component of the cis-Golgi vesicle tethering machinery.

Q9SWH4	SYP42_ARATH	Syntaxin-42	10888666	AtVPS45 complex formation at the trans-Golgi network.

O00585	CCL21_HUMAN	C-C motif chemokine 21	9235955	Molecular cloning of a novel human CC chemokine secondary lymphoid- tissue chemokine that is a potent chemoattractant for lymphocytes and mapped to chromosome 9p13.

Q9GPF1	AP3M_DICDI	AP-3 complex subunit mu	17010123	A role for adaptor protein-3 complex in the organization of the endocytic pathway in Dictyostelium.

P36033	FRE2_YEAST	Ferric/cupric reductase transmembrane component 2	8164662	Two distinctly regulated genes are required for ferric reduction, the first step of iron uptake in Saccharomyces cerevisiae.

P84789	PHIG1_SARGI	Philibertain g 1	16328737	Philibertain g I, the most basic cysteine endopeptidase purified from the latex of Philibertia gilliesii Hook. et Arn. (Apocynaceae).

P84678	SC31_TITCA	Toxin Tc31	15025998	Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

Q9UT30	YKG6_SCHPO	Putative nucleus export protein C8F11.06	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UBH0	IL1F5_HUMAN	Interleukin-1 family member 5	10512743	IL1HY1: a novel interleukin-1 receptor antagonist gene.

Q10308	MUG43_SCHPO	Meiotically up-regulated gene 43 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P38850	RT107_YEAST	Regulator of Ty1 transposition protein 107	14988729	Esc4p, a new target of Mec1p (ATR), promotes resumption of DNA synthesis after DNA damage.

O74563	BRL2_SCHPO	E3 ubiquitin-protein ligase brl2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q96RK4	BBS4_HUMAN	Bardet-Biedl syndrome 4 protein	17574030	A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis.

Q6WV19	GALT2_DROME	Polypeptide N-acetylgalactosaminyltransferase 2	12829714	Functional characterization and expression analysis of members of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family from Drosophila melanogaster.

Q13464	ROCK1_HUMAN	Rho-associated protein kinase 1	10436159	Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase.

Q4GWU5	SFTI1_HELAN	Trypsin inhibitor 1	10390350	High-resolution structure of a potent, cyclic proteinase inhibitor from sunflower seeds.

Q9DCD6	GBRAP_MOUSE	Gamma-aminobutyric acid receptor-associated protein	10900017	The gamma-aminobutyric acid type A receptor (GABAAR)-associated protein GABARAP interacts with gephyrin but is not involved in receptor anchoring at the synapse.

P22953	HSP71_ARATH	Heat shock cognate 70 kDa protein 1	20543027	The deubiquitinating enzyme AMSH3 is required for intracellular trafficking and vacuole biogenesis in Arabidopsis thaliana.

Q9VSF2	MED24_DROME	Mediator of RNA polymerase II transcription subunit 24	12021283	Novel Mediator proteins of the small Mediator complex in Drosophila SL2 cells.

Q96P56	CTSR2_HUMAN	Cation channel sperm-associated protein 2	16740636	Association of Catsper1 or -2 with Ca(v)3.3 leads to suppression of T-type calcium channel activity.

Q94517	HDAC1_DROME	Histone deacetylase Rpd3	11571273	Physical and functional association of SU(VAR)3-9 and HDAC1 in Drosophila.

Q9H307	PININ_HUMAN	Pinin	8922384	Characterization of pinin, a novel protein associated with the desmosome-intermediate filament complex.

P53384	NUBP1_HUMAN	Cytosolic Fe-S cluster assembly factor NUBP1	18573874	Human Nbp35 is essential for both cytosolic iron-sulfur protein assembly and iron homeostasis.

Q6A078	CE290_MOUSE	Centrosomal protein of 290 kDa	16682973	The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4.

Q13308	PTK7_HUMAN	Tyrosine-protein kinase-like 7	8882711	Characterization of the human full-length PTK7 cDNA encoding a receptor protein tyrosine kinase-like molecule closely related to chick KLG.

P25115	DRD5_RAT	D(1B) dopamine receptor	1831904	Cloning, molecular characterization, and chromosomal assignment of a gene encoding a second D1 dopamine receptor subtype: differential expression pattern in rat brain compared with the D1A receptor.

P27248	GCST_ECOLI	Aminomethyltransferase	8375392	Cloning and nucleotide sequence of the gcv operon encoding the Escherichia coli glycine-cleavage system.

Q13309	SKP2_HUMAN	S-phase kinase-associated protein 2	7553852	p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase.

P52954	LBX1_HUMAN	Transcription factor LBX1	8645601	Mouse Lbx1 and human LBX1 define a novel mammalian homeobox gene family related to the Drosophila lady bird genes.

P19474	RO52_HUMAN	E3 ubiquitin-protein ligase TRIM21	16472766	UnpEL/Usp4 is ubiquitinated by Ro52 and deubiquitinated by itself.

P31146	COR1A_HUMAN	Coronin-1A	7758584	Molecular cloning of a novel actin-binding protein, p57, with a WD repeat and a leucine zipper motif.

Q80TQ2	CYLD_MOUSE	Ubiquitin carboxyl-terminal hydrolase CYLD	16713561	Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling.

Q93V99	PDF2_ARATH	Homeobox-leucine zipper protein PROTODERMAL FACTOR 2	12505995	Regulation of shoot epidermal cell differentiation by a pair of homeodomain proteins in Arabidopsis.

Q55CS9	ATPB_DICDI	ATP synthase subunit beta, mitochondrial	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

O76082	S22A5_HUMAN	Solute carrier family 22 member 5	9916797	Primary systemic carnitine deficiency is caused by mutations in a gene encoding sodium ion-dependent carnitine transporter.

P53048	MAL11_YEAST	General alpha-glucoside permease	8594329	Characterization of AGT1 encoding a general alpha-glucoside transporter from Saccharomyces.

O22040	ANP1_ARATH	Mitogen-activated protein kinase kinase kinase ANP1	10717008	Functional analysis of oxidative stress-activated mitogen-activated protein kinase cascade in plants.

P36618	CDC16_SCHPO	Cell division control protein 16	8334988	The S. pombe cdc16 gene is required both for maintenance of p34cdc2 kinase activity and regulation of septum formation: a link between mitosis and cytokinesis?

Q9ES82	POPD2_MOUSE	Popeye domain-containing protein 2	10882522	Isolation and characterization of the novel popeye gene family expressed in skeletal muscle and heart.

Q09167	SRSF5_RAT	Serine/arginine-rich splicing factor 5	7686911	Novel delayed-early and highly insulin-induced growth response genes. Identification of HRS, a potential regulator of alternative pre-mRNA splicing.

P38315	YBP1_YEAST	YAP1-binding protein 1	14562095	Global analysis of protein localization in budding yeast.

Q9M099	SCP24_ARATH	Serine carboxypeptidase 24	11320207	BRS1, a serine carboxypeptidase, regulates BRI1 signaling in Arabidopsis thaliana.

Q9Y0T2	FBXA_DICDI	F-box/WD repeat-containing protein A	11390363	Regulated protein degradation controls PKA function and cell-type differentiation in Dictyostelium.

P50503	F10A1_RAT	Hsc70-interacting protein	7585962	Hip, a novel cochaperone involved in the eukaryotic Hsc70/Hsp40 reaction cycle.

Q9Z143	SEM4F_RAT	Semaphorin-4F	10051670	Cloning, expression, and genetic mapping of Sema W, a member of the semaphorin family.

Q16666	IF16_HUMAN	Gamma-interferon-inducible protein 16	7536752	IFI 16 gene encodes a nuclear protein whose expression is induced by interferons in human myeloid leukaemia cell lines.

Q8AXX8	SOX10_XENLA	Transcription factor Sox-10	12812785	Sox10 regulates the development of neural crest-derived melanocytes in Xenopus.

P24612	MEC4_CAEEL	Degenerin mec-4	8655580	Sequence and transmembrane topology of MEC-4, an ion channel subunit required for mechanotransduction in Caenorhabditis elegans.

O76187	DARA_DICDI	Darlin	9802899	Identification of darlin, a Dictyostelium protein with Armadillo-like repeats that binds to small GTPases and is important for the proper aggregation of developing cells.

Q9QXN0	SHRM3_MOUSE	Protein Shroom3	16249236	Shroom regulates epithelial cell shape via the apical positioning of an actomyosin network.

P40541	SCC3_YEAST	Cohesin subunit SCC3	11983169	Molecular architecture of SMC proteins and the yeast cohesin complex.

Q10432	CCQ1_SCHPO	Coiled-coil quantitatively-enriched protein 1	17289569	SHREC, an effector complex for heterochromatic transcriptional silencing.

O75410	TACC1_HUMAN	Transforming acidic coiled-coil-containing protein 1	12165861	Carcinogenesis and translational controls: TACC1 is down-regulated in human cancers and associates with mRNA regulators.

Q0IMG9	SL11_ORYSJ	E3 ubiquitin-protein ligase SPL11	15377756	Spotted leaf11, a negative regulator of plant cell death and defense, encodes a U-Box/Armadillo repeat protein endowed with E3 Ubiquitin ligase activity.

P51610	HCFC1_HUMAN	Host cell factor 1	12670868	Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell- proliferation factor HCF-1.

O14202	MU116_SCHPO	Meiotically up-regulated gene 116 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9H1D9	RPC6_HUMAN	DNA-directed RNA polymerase III subunit RPC6	19631370	RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway.

Q96AV8	E2F7_HUMAN	Transcription factor E2F7	15133492	E2F-7: a distinctive E2F family member with an unusual organization of DNA-binding domains.

P01243	CSH_HUMAN	Chorionic somatomammotropin hormone	593368	Construction and analysis of recombinant DNA for human chorionic somatomammotropin.

P36126	SPO14_YEAST	Phospholipase D1	8576189	Identification and characterization of a gene encoding phospholipase D activity in yeast.

O60755	GALR3_HUMAN	Galanin receptor type 3	9832121	Molecular characterization and expression of cloned human galanin receptors GALR2 and GALR3.

Q9QY16	DDX25_RAT	ATP-dependent RNA helicase DDX25	10608860	A novel gonadotropin-regulated testicular RNA helicase: a new member of the DEAD-box family.

Q14790	CASP8_HUMAN	Caspase-8	9334338	p28 Bap31, a Bcl-2/Bcl-XL- and procaspase-8-associated protein in the endoplasmic reticulum.

Q63434	PLGF_RAT	Placenta growth factor	7706320	Purification and characterization of a naturally occurring vascular endothelial growth factor.placenta growth factor heterodimer.

Q07457	BRE1_YEAST	E3 ubiquitin-protein ligase BRE1	12876294	The Paf1 complex is essential for histone monoubiquitination by the Rad6-Bre1 complex, which signals for histone methylation by COMPASS and Dot1p.

P47932	REL1_MOUSE	Prorelaxin 1	8216305	Mouse relaxin: synthesis and biological activity of the first relaxin with an unusual crosslinking pattern.

Q06559	RS3_DROME	40S ribosomal protein S3	8641296	A Drosophila ribosomal protein contains 8-oxoguanine and abasic site DNA repair activities.

P60058	SC61G_CANFA	Protein transport protein Sec61 subunit gamma	8107851	Evolutionary conservation of components of the protein translocation complex.

Q14CM0	FRPD4_HUMAN	FERM and PDZ domain-containing protein 4	19118189	Preso, a novel PSD-95-interacting FERM and PDZ domain protein that regulates dendritic spine morphogenesis.

Q9W0G1	PTP61_DROME	Tyrosine-protein phosphatase non-receptor type 61F	8463208	Alternative splicing gives rise to a nuclear protein tyrosine phosphatase in Drosophila.

O14131	MU191_SCHPO	Meiotically up-regulated gene 191 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UGL1	KDM5B_HUMAN	Lysine-specific demethylase 5B	12657635	Human PLU-1 has transcriptional repression properties and interacts with the developmental transcription factors BF-1 and PAX9.

Q12089	AEP3_YEAST	ATPase expression protein 3	14562095	Global analysis of protein localization in budding yeast.

Q9NZJ0	DTL_HUMAN	Denticleless protein homolog	18794347	PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex.

O14595	CTDS2_HUMAN	Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2	9315096	Characterization of a highly conserved gene (OS4) amplified with CDK4 in human sarcomas.

P17792	VIRB2_AGRT5	Protein virB2	2233252	Characterization of the virB operon of an Agrobacterium tumefaciens Ti plasmid: nucleotide sequence and protein analysis.

O94397	SGF73_SCHPO	SAGA-associated factor 73	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q76K27	SIAT2_MOUSE	Beta-galactoside alpha-2,6-sialyltransferase 2	12966079	Comparison of the enzymatic properties of mouse beta-galactoside alpha2,6-sialyltransferases, ST6Gal I and II.

P27612	PLAP_MOUSE	Phospholipase A-2-activating protein	2052621	Cloning of a phospholipase A2-activating protein.

Q9ULX5	RN112_HUMAN	RING finger protein 112	8660987	Chromosome mapping of human (ZNF179), mouse, and rat genes for brain finger protein (bfp), a member of the RING finger family.

Q9W0P3	MED30_DROME	Mediator of RNA polymerase II transcription subunit 30	12021283	Novel Mediator proteins of the small Mediator complex in Drosophila SL2 cells.

P50554	GABT_RAT	4-aminobutyrate aminotransferase, mitochondrial	10447691	The mature size of rat 4-aminobutyrate aminotransferase is different in liver and brain.

P32048	SYKM_YEAST	Lysyl-tRNA synthetase, mitochondrial	2016746	Structure and evolution of a group of related aminoacyl-tRNA synthetases.

P08373	MURB_ECOLI	UDP-N-acetylenolpyruvoylglucosamine reductase	8448160	Overexpression, purification, and mechanistic study of UDP-N- acetylenolpyruvylglucosamine reductase.

Q9SYK4	IP5PD_ARATH	Type I inositol-1,4,5-trisphosphate 5-phosphatase 13	18931139	Interaction of the WD40 domain of a myoinositol polyphosphate 5- phosphatase with SnRK1 links inositol, sugar, and stress signaling.

Q9C5S8	CRK5_ARATH	Cysteine-rich receptor-like protein kinase 5	15604743	Activation of hypersensitive cell death by pathogen-induced receptor- like protein kinases from Arabidopsis.

P15559	NQO1_HUMAN	NAD(P)H dehydrogenase [quinone] 1	2843525	Human dioxin-inducible cytosolic NAD(P)H:menadione oxidoreductase. cDNA sequence and localization of gene to chromosome 16.

P55863	SOX3A_XENLA	Transcription factor Sox-3-A	15302595	Repression of nodal expression by maternal B1-type SOXs regulates germ layer formation in Xenopus and zebrafish.

Q63768	CRK_RAT	Adapter molecule crk	12198159	Tyrosine 221 in Crk regulates adhesion-dependent membrane localization of Crk and Rac and activation of Rac signaling.

Q14934	NFAC4_HUMAN	Nuclear factor of activated T-cells, cytoplasmic 4	7749981	Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins.

O43293	DAPK3_HUMAN	Death-associated protein kinase 3	9488481	ZIP kinase, a novel serine/threonine kinase which mediates apoptosis.

P54753	EPHB3_HUMAN	Ephrin type-B receptor 3	8397371	PCR mediated detection of a new human receptor-tyrosine-kinase, HEK 2.

P43616	DUG1_YEAST	Cys-Gly metallodipeptidase DUG1	19346245	Dug1p Is a Cys-Gly peptidase of the gamma-glutamyl cycle of Saccharomyces cerevisiae and represents a novel family of Cys-Gly peptidases.

P53188	CGR1_YEAST	rRNA-processing protein CGR1	11116400	Cgr1p, a novel nucleolar protein encoded by Saccharomyces cerevisiae orf YGL0292w.

Q9QWV4	MLF1_MOUSE	Myeloid leukemia factor 1	12176995	MADM, a novel adaptor protein that mediates phosphorylation of the 14-3-3 binding site of myeloid leukemia factor 1.

Q9LKZ3	RBR1_ARATH	Retinoblastoma-related protein 1	16377572	The RETINOBLASTOMA-RELATED gene regulates stem cell maintenance in Arabidopsis roots.

P62826	RAN_HUMAN	GTP-binding nuclear protein Ran	8421051	Ran/TC4: a small nuclear GTP-binding protein that regulates DNA synthesis.

B7ZQA9	P5F12_XENLA	POU domain, class 5, transcription factor 1.2	17541407	POU-V factors antagonize maternal VegT activity and beta-Catenin signaling in Xenopus embryos.

Q9Y6E7	SIRT4_HUMAN	NAD-dependent ADP-ribosyltransferase sirtuin-4	17715127	Regulation of insulin secretion by SIRT4, a mitochondrial ADP- ribosyltransferase.

Q9SZF7	SHR_ARATH	Protein SHORT-ROOT	10850497	The SHORT-ROOT gene controls radial patterning of the Arabidopsis root through radial signaling.

P26368	U2AF2_HUMAN	Splicing factor U2AF 65 kDa subunit	9447963	Sip1, a novel RS domain-containing protein essential for pre-mRNA splicing.

P40008	FMP52_YEAST	Protein FMP52, mitochondrial	16407407	Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins.

P48169	GBRA4_HUMAN	Gamma-aminobutyric acid receptor subunit alpha-4	8719416	Cloning and characterization of the human GABAA receptor alpha 4 subunit: identification of a unique diazepam-insensitive binding site.

O43283	M3K13_HUMAN	Mitogen-activated protein kinase kinase kinase 13	9353328	Molecular cloning and functional expression of a cDNA encoding a new member of mixed lineage protein kinase from human brain.

Q61686	CBX5_MOUSE	Chromobox protein homolog 5	8978696	A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors.

Q9LEX0	P2A13_ARATH	F-box protein PP2-A13	12169662	The F-box subunit of the SCF E3 complex is encoded by a diverse superfamily of genes in Arabidopsis.

P12371	FCERA_RAT	High affinity immunoglobulin epsilon receptor subunit alpha	2522441	The gene for the rat mast cell high affinity IgE receptor alpha chain. Structure and alternative mRNA splicing patterns.

Q9C5C2	BGL37_ARATH	Myrosinase 2	16640593	Arabidopsis myrosinases TGG1 and TGG2 have redundant function in glucosinolate breakdown and insect defense.

P26359	MSH3_SCHPO	DNA mismatch repair protein msh3	11333218	Requirement for Msh6, but not for Swi4 (Msh3), in Msh2-dependent repair of base-base mismatches and mononucleotide loops in Schizosaccharomyces pombe.

Q75N73	S39AE_MOUSE	Zinc transporter ZIP14	16950869	Zip14 (Slc39a14) mediates non-transferrin-bound iron uptake into cells.

Q9CXH7	SGOL1_MOUSE	Shugoshin-like 1	18084284	Unified mode of centromeric protection by shugoshin in mammalian oocytes and somatic cells.

Q13324	CRFR2_HUMAN	Corticotropin-releasing factor receptor 2	8536644	Cloning and characterization of the human corticotropin-releasing factor-2 receptor complementary deoxyribonucleic acid.

Q6R0H1	LHY_ARATH	Protein LHY	10535927	The protein kinase CK2 is involved in regulation of circadian rhythms in Arabidopsis.

Q8ND56	LS14A_HUMAN	Protein LSM14 homolog A	17074753	RAP55, a cytoplasmic mRNP component, represses translation in Xenopus oocytes.

O81445	CNBL1_ARATH	Calcineurin B-like protein 1	11115898	Interaction specificity of Arabidopsis calcineurin B-like calcium sensors and their target kinases.

Q12107	APC9_YEAST	Anaphase-promoting complex subunit 9	9469814	Mass spectrometric analysis of the anaphase-promoting complex from yeast: identification of a subunit related to cullins.

P15088	CBPA3_HUMAN	Mast cell carboxypeptidase A	2594780	Cloning of cDNAs that encode human mast cell carboxypeptidase A, and comparison of the protein with mouse mast cell carboxypeptidase A and rat pancreatic carboxypeptidases.

P08922	ROS_HUMAN	Proto-oncogene tyrosine-protein kinase ROS	3785223	Characterization of an activated human ros gene.

Q9YHV4	FSTA_DANRE	Follistatin-A	16890217	Noggin1 and Follistatin-like2 function redundantly to Chordin to antagonize BMP activity.

Q5FW85	ECM2_MOUSE	Extracellular matrix protein 2	18757743	Transcriptome-based systematic identification of extracellular matrix proteins.

Q9Y210	TRPC6_HUMAN	Short transient receptor potential channel 6	9930701	Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol.

P24783	DBP2_YEAST	ATP-dependent RNA helicase DBP2	11585918	Absence of Dbp2p alters both nonsense-mediated mRNA decay and rRNA processing.

O16829	CECC_DROME	Cecropin-C	1740152	CecC, a cecropin gene expressed during metamorphosis in Drosophila pupae.

O48737	TRXM1_ARATH	Thioredoxin M1, chloroplastic	19825612	Prompt and easy activation by specific thioredoxins of calvin cycle enzymes of Arabidopsis thaliana associated in the GAPDH/CP12/PRK supramolecular complex.

O70373	XIRP1_MOUSE	Xin actin-binding repeat-containing protein 1	17766470	Loss of mXinalpha, an intercalated disk protein, results in cardiac hypertrophy and cardiomyopathy with conduction defects.

Q60674	NR1D2_MOUSE	Nuclear receptor subfamily 1 group D member 2	7838156	Identification of RVR, a novel orphan nuclear receptor that acts as a negative transcriptional regulator.

Q8TBA6	GOGA5_HUMAN	Golgin subfamily A member 5	9915833	Identification and characterization of golgin-84, a novel Golgi integral membrane protein with a cytoplasmic coiled-coil domain.

Q6UVJ0	SAS6_HUMAN	Spindle assembly abnormal protein 6 homolog	15665853	SAS-6 defines a protein family required for centrosome duplication in C. elegans and in human cells.

P40958	MAD2_YEAST	Mitotic spindle checkpoint component MAD2	10436016	The spindle checkpoint of budding yeast depends on a tight complex between the Mad1 and Mad2 proteins.

O88446	S22A3_RAT	Solute carrier family 22 member 3	9830022	Identity of the organic cation transporter OCT3 as the extraneuronal monoamine transporter (uptake2) and evidence for the expression of the transporter in the brain.

P01713	LV210_HUMAN	Ig lambda chain V-II region NIG-58	6787031	Comparative studies on the structure of the light chains of human immunoglobulins. III. Amino acid sequence of a lambda type Bence Jones euglobulin.

Q95RW8	OPTIX_DROME	Protein Optix	10381573	Six class homeobox genes in Drosophila belong to three distinct families and are involved in head development.

O95817	BAG3_HUMAN	BAG family molecular chaperone regulator 3	9873016	An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators.

P23771	GATA3_HUMAN	Trans-acting T-cell-specific transcription factor GATA-3	2050118	A T-cell specific TCR delta DNA binding protein is a member of the human GATA family.

Q9JLT4	TRXR2_MOUSE	Thioredoxin reductase 2, mitochondrial	10455115	Redox regulation of cell signaling by selenocysteine in mammalian thioredoxin reductases.

P38111	ATR_YEAST	Serine/threonine-protein kinase MEC1	10950868	The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast.

O42601	S17B1_XENLA	Transcription factor Sox-17-beta.1	15157240	Early endodermal expression of the Xenopus Endodermin gene is driven by regulatory sequences containing essential Sox protein-binding elements.

Q09843	RFC2_SCHPO	Replication factor C subunit 2	16040599	Contrasting effects of Elg1-RFC and Ctf18-RFC inactivation in the absence of fully functional RFC in fission yeast.

P41251	NRAM1_MOUSE	Natural resistance-associated macrophage protein 1	8490962	Natural resistance to infection with intracellular parasites: isolation of a candidate for Bcg.

Q8WXG6	MADD_HUMAN	MAP kinase-activating death domain protein	9115275	MADD, a novel death domain protein that interacts with the type 1 tumor necrosis factor receptor and activates mitogen-activated protein kinase.

O49686	PYR1_ARATH	Abscisic acid receptor PYR1	19898420	A gate-latch-lock mechanism for hormone signalling by abscisic acid receptors.

P14954	CECA_DROME	Cecropin-A1/A2	2390977	The immune response in Drosophila: pattern of cecropin expression and biological activity.

Q9P2N4	ATS9_HUMAN	A disintegrin and metalloproteinase with thrombospondin motifs 9	12514189	Characterization of ADAMTS-9 and ADAMTS-20 as a distinct ADAMTS subfamily related to Caenorhabditis elegans GON-1.

Q9SDL7	HMT1_ARATH	Homocysteine S-methyltransferase 1	10747987	Characterization and functional expression of cDNAs encoding methionine-sensitive and -insensitive homocysteine S- methyltransferases from Arabidopsis.

O96001	GSUB_HUMAN	G-substrate	10051666	Molecular identification of human G-substrate, a possible downstream component of the cGMP-dependent protein kinase cascade in cerebellar Purkinje cells.

Q03529	SCS7_YEAST	Ceramide very long chain fatty acid hydroxylase SCS7	14562095	Global analysis of protein localization in budding yeast.

Q9SE43	REV_ARATH	Homeobox-leucine zipper protein REVOLUTA	11169198	REVOLUTA regulates meristem initiation at lateral positions.

P30620	PSO2_YEAST	DNA cross-link repair protein PSO2/SNM1	12509272	The beta-lactamase motif in Snm1 is required for repair of DNA double-strand breaks caused by interstrand crosslinks in S. cerevisiae.

P08F94	PKHD1_HUMAN	Fibrocystin	11919560	The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein.

Q38802	KSA_ARATH	Ent-copalyl diphosphate synthase, chloroplastic	7994182	The Arabidopsis GA1 locus encodes the cyclase ent-kaurene synthetase A of gibberellin biosynthesis.

P54362	AP3D_DROME	AP-3 complex subunit delta	10659786	A genetic and molecular characterization of the garnet gene of Drosophila melanogaster.

Q20010	SAS5_CAEEL	Spindle assembly abnormal protein 5	15572125	Centriole assembly requires both centriolar and pericentriolar material proteins.

Q09855	POF11_SCHPO	F-box/WD repeat-containing protein pof11	15147268	Molecular interactions of fission yeast Skp1 and its role in the DNA damage checkpoint.

P0A7G2	RBFA_ECOLI	Ribosome-binding factor A	9422595	RimM and RbfA are essential for efficient processing of 16S rRNA in Escherichia coli.

O70277	TRIM3_RAT	Tripartite motif-containing protein 3	10673389	BERP, a novel ring finger protein, binds to alpha-actinin-4.

Q5BDV3	ABFC_EMENI	Alpha-N-arabinofuranosidase C	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

Q8L735	ISOA2_ARATH	Isoamylase 2, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q06406	LSM6_YEAST	U6 snRNA-associated Sm-like protein LSm6	15075370	An Lsm2-Lsm7 complex in Saccharomyces cerevisiae associates with the small nucleolar RNA snR5.

P53940	APJ1_YEAST	J domain-containing protein APJ1	14562095	Global analysis of protein localization in budding yeast.

Q9FGM0	FTSHB_ARATH	ATP-dependent zinc metalloprotease FTSH 11, chloroplastic/mitochondrial	14630971	Coordinated regulation and complex formation of yellow variegated1 and yellow variegated2, chloroplastic FtsH metalloproteases involved in the repair cycle of photosystem II in Arabidopsis thylakoid membranes.

P02293	H2B1_YEAST	Histone H2B.1	11973294	A role for histone H2B during repair of UV-induced DNA damage in Saccharomyces cerevisiae.

Q10223	POF14_SCHPO	F-box protein pof14	17016471	Repression of ergosterol level during oxidative stress by fission yeast F-box protein Pof14 independently of SCF.

P86052	CYC4_THIRO	Cytochrome c4	18085548	De novo sequencing of a 21-kDa cytochrome c4 from Thiocapsa roseopersicina by nanoelectrospray ionization ion-trap and Fourier- transform ion-cyclotron resonance mass spectrometry.

P02549	SPTA1_HUMAN	Spectrin alpha chain, erythrocyte	1634521	Properties of human red cell spectrin heterodimer (side-to-side) assembly and identification of an essential nucleation site.

Q16676	FOXD1_HUMAN	Forkhead box protein D1	7957066	Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending.

Q9JMF7	DOPP1_MOUSE	Dolichyldiphosphatase 1	12198133	Identification and characterization of a cDNA encoding a dolichyl pyrophosphate phosphatase located in the endoplasmic reticulum of mammalian cells.

Q9WU62	INCE_MOUSE	Inner centromere protein	12584241	Dynamic relocalization of the chromosomal passenger complex proteins inner centromere protein (INCENP) and aurora-B kinase during male mouse meiosis.

Q9ATB4	TAD2B_ARATH	Transcriptional adapter ADA2b	12747832	PROPORZ1, a putative Arabidopsis transcriptional adaptor protein, mediates auxin and cytokinin signals in the control of cell proliferation.

P40963	SAS2_YEAST	Histone acetyltransferase SAS2	11731479	The yeast SAS (something about silencing) protein complex contains a MYST-type putative acetyltransferase and functions with chromatin assembly factor ASF1.

Q96S37	S22AC_HUMAN	Solute carrier family 22 member 12	14694169	Clinical and molecular analysis of patients with renal hypouricemia in Japan-influence of URAT1 gene on urinary urate excretion.

P51862	ROM2_YEAST	RHO1 GDP-GTP exchange protein 2	8641285	Rom1p and Rom2p are GDP/GTP exchange proteins (GEPs) for the Rho1p small GTP binding protein in Saccharomyces cerevisiae.

P69851	DAD4_YEAST	DASH complex subunit DAD4	12408861	Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase Ipl1p.

Q54GP3	SPRE_DICDI	Sepiapterin reductase	15896778	D-threo-tetrahydrobiopterin is synthesized via 1'-oxo-2'-D- hydroxypropyl-tetrahydropterin in Dictyostelium discoideum Ax2.

P83663	RACYE_RANES	Ranacyclin-E	14636071	Ranacyclins, a new family of short cyclic antimicrobial peptides: biological function, mode of action and parameters involved in target specificity.

P38757	NEM1_YEAST	Nuclear envelope morphology protein 1	15889145	The yeast lipin Smp2 couples phospholipid biosynthesis to nuclear membrane growth.

O88552	CLD2_MOUSE	Claudin-2	10601346	Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins.

Q9Y6Q3	ZFP37_HUMAN	Zinc finger protein 37 homolog	9585434	Cloning, characterization, and chromosomal assignment of the human ortholog of murine Zfp-37, a candidate gene for Nager syndrome.

P00330	ADH1_YEAST	Alcohol dehydrogenase 1	6985717	Isolation of the structural gene for alcohol dehydrogenase by genetic complementation in yeast.

Q9JLB4	CUBN_MOUSE	Cubilin	15342463	Mouse amnionless, which is required for primitive streak assembly, mediates cell-surface localization and endocytic function of cubilin on visceral endoderm and kidney proximal tubules.

P53492	ACT7_ARATH	Actin-7	11449050	One plant actin isovariant, ACT7, is induced by auxin and required for normal callus formation.

O43303	CE110_HUMAN	Centrosomal protein of 110 kDa	19460342	Cep76, a centrosomal protein that specifically restrains centriole reduplication.

Q06144	ORM2_YEAST	Protein ORM2	14562095	Global analysis of protein localization in budding yeast.

P51572	BAP31_HUMAN	B-cell receptor-associated protein 31	15024066	The yeast split-ubiquitin membrane protein two-hybrid screen identifies BAP31 as a regulator of the turnover of endoplasmic reticulum-associated protein tyrosine phosphatase-like B.

Q29016	ACRBP_PIG	Acrosin-binding protein	8144514	An acrosomal protein, sp32, mammalian sperm is a binding protein specific for two proacrosins and an acrosin intermediate.

P07093	GDN_HUMAN	Glia-derived nexin	3997857	Protease nexin. Properties and a modified purification procedure.

O94811	TPPP_HUMAN	Tubulin polymerization-promoting protein	15590652	p25alpha Stimulates alpha-synuclein aggregation and is co-localized with aggregated alpha-synuclein in alpha-synucleinopathies.

O75897	ST1C4_HUMAN	Sulfotransferase 1C4	9852044	Molecular cloning, expression, and characterization of novel human SULT1C sulfotransferases that catalyze the sulfonation of N-hydroxy-2- acetylaminofluorene.

P98168	ZXDA_HUMAN	Zinc finger X-linked protein ZXDA	17493635	The zinc finger proteins ZXDA and ZXDC form a complex that binds CIITA and regulates MHC II gene transcription.

Q9Y6J8	STYL1_HUMAN	Serine/threonine/tyrosine-interacting-like protein 1	9757831	Gathering STYX: phosphatase-like form predicts functions for unique protein-interaction domains.

Q9VVX5	NESSY_DROME	Transmembrane protein nessy	10446276	nessy, an evolutionary conserved gene controlled by Hox proteins during Drosophila embryogenesis.

Q90WW4	IGF2A_XENLA	Insulin-like growth factor II-A	11709186	Neural and head induction by insulin-like growth factor signals.

Q9V460	SPT5H_DROME	Transcription elongation factor SPT5	12934007	Tracking FACT and the RNA polymerase II elongation complex through chromatin in vivo.

P42697	DRP1A_ARATH	Dynamin-related protein 1A	12671086	Members of the Arabidopsis dynamin-like gene family, ADL1, are essential for plant cytokinesis and polarized cell growth.

Q9UIG0	BAZ1B_HUMAN	Tyrosine-protein kinase BAZ1B	10662543	A novel family of bromodomain genes.

Q9DA73	CCD89_MOUSE	Coiled-coil domain-containing protein 89	14648848	Identification of BOIP, a novel cDNA highly expressed during spermatogenesis that encodes a protein interacting with the orange domain of the hairy-related transcription factor HRT1/Hey1 in Xenopus and mouse.

P84691	SC61_TITCA	Toxin Tc61	15025998	Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

Q12300	RGT2_YEAST	High-affinity glucose transporter RGT2	8901598	Two glucose transporters in Saccharomyces cerevisiae are glucose sensors that generate a signal for induction of gene expression.

O96838	FYV1_DROME	Putative 1-phosphatidylinositol-3-phosphate 5-kinase	16837550	Fab1 phosphatidylinositol 3-phosphate 5-kinase controls trafficking but not silencing of endocytosed receptors.

Q24139	COMM_DROME	Protein commissureless	12165468	Drosophila Nedd4, a ubiquitin ligase, is recruited by Commissureless to control cell surface levels of the roundabout receptor.

Q9C0Y4	AGLU_SCHPO	Alpha-glucosidase	11298744	Carboxyl group of residue Asp647 as possible proton donor in catalytic reaction of alpha-glucosidase from Schizosaccharomyces pombe.

Q08406	CNTFR_RAT	Ciliary neurotrophic factor receptor subunit alpha	8381290	The alpha component of the CNTF receptor is required for signaling and defines potential CNTF targets in the adult and during development.

O04719	P2C77_ARATH	Protein phosphatase 2C 77	14504388	A novel domain in the protein kinase SOS2 mediates interaction with the protein phosphatase 2C ABI2.

Q9T076	ENL2_ARATH	Early nodulin-like protein 2	12805588	Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis.

P35269	T2FA_HUMAN	General transcription factor IIF subunit 1	1734283	Characterization of cDNA for the large subunit of the transcription initiation factor TFIIF.

O94449	RFC4_SCHPO	Replication factor C subunit 4	16040599	Contrasting effects of Elg1-RFC and Ctf18-RFC inactivation in the absence of fully functional RFC in fission yeast.

Q6REY9	RHG20_RAT	Rho GTPase-activating protein 20	15234003	Identification of RARhoGAP, a novel putative RhoGAP gene expressed in male germ cells.

P53670	LIMK2_RAT	LIM domain kinase 2	7651734	LIMK-1 and LIMK-2, two members of a LIM motif-containing protein kinase family.

P55103	INHBC_HUMAN	Inhibin beta C chain	7826378	Cloning of a new member of the TGF-beta family: a putative new activin beta C chain.

Q02078	MEF2A_HUMAN	Myocyte-specific enhancer factor 2A	1516833	Human myocyte-specific enhancer factor 2 comprises a group of tissue- restricted MADS box transcription factors.

Q14676	MDC1_HUMAN	Mediator of DNA damage checkpoint protein 1	17525332	ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

O60858	TRI13_HUMAN	E3 ubiquitin-protein ligase TRIM13	11331580	The tripartite motif family identifies cell compartments.

P46598	HSP90_CANAL	Heat shock protein 90 homolog	7591093	Structure and regulation of the HSP90 gene from the pathogenic fungus Candida albicans.

Q8BH52	CR3L2_MOUSE	Cyclic AMP-responsive element-binding protein 3-like protein 2	19767744	Regulation of endoplasmic reticulum stress response by a BBF2H7- mediated Sec23a pathway is essential for chondrogenesis.

Q8BUV6	LSM11_MOUSE	U7 snRNA-associated Sm-like protein LSm11	16087681	Toward an assembly line for U7 snRNPs: interactions of U7-specific Lsm proteins with PRMT5 and SMN complexes.

P38165	RTG3_YEAST	Retrograde regulation protein 3	9032238	A basic helix-loop-helix-leucine zipper transcription complex in yeast functions in a signaling pathway from mitochondria to the nucleus.

P35663	CYLC1_HUMAN	Cylicin-1	8354692	Molecular characterization of mammalian cylicin, a basic protein of the sperm head cytoskeleton.

Q96RU2	UBP28_HUMAN	Ubiquitin carboxyl-terminal hydrolase 28	18662541	The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint.

Q91770	NOT2_XENLA	Homeobox protein not2	8626017	Overexpression of the homeobox gene Xnot-2 leads to notochord formation in Xenopus.

Q9D7I0	SHSA5_MOUSE	Protein shisa-5	12135983	Scotin, a novel p53-inducible proapoptotic protein located in the ER and the nuclear membrane.

P10636	TAU_HUMAN	Microtubule-associated protein tau	2498079	Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain.

Q9H9B1	EHMT1_HUMAN	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5	12004135	A complex with chromatin modifiers that occupies E2F- and Myc- responsive genes in G0 cells.

Q95YH0	CDK8_DICDI	Probable cyclin-dependent kinase 8	12060071	A novel Dictyostelium Cdk8 is required for aggregation, but is dispensable for growth.

O35473	C1D_MOUSE	Nuclear nucleic acid-binding protein C1D	9405624	Cloning and characterization of a corepressor and potential component of the nuclear hormone receptor repression complex.

Q84LH8	PIF5_ARATH	Transcription factor PIF5	18065691	The basic helix-loop-helix transcription factor PIF5 acts on ethylene biosynthesis and phytochrome signaling by distinct mechanisms.

P38797	PP2C7_YEAST	Protein phosphatase 2C homolog 7, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q9Y581	INSL6_HUMAN	Insulin-like peptide INSL6	10598589	Cloning of two novel mammalian paralogs of relaxin/insulin family proteins and their expression in testis and kidney.

P25071	CML12_ARATH	Calmodulin-like protein 12	7827491	Arabidopsis TCH3 encodes a novel Ca2+ binding protein and shows environmentally induced and tissue-specific regulation.

Q60716	P4HA2_MOUSE	Prolyl 4-hydroxylase subunit alpha-2	7753822	Cloning, baculovirus expression, and characterization of a second mouse prolyl 4-hydroxylase alpha-subunit isoform: formation of an alpha 2 beta 2 tetramer with the protein disulfide-isomerase/beta subunit.

P17429	AREA_EMENI	Nitrogen regulatory protein areA	15537757	Modulation of the ligand binding properties of the transcription repressor NmrA by GATA-containing DNA and site-directed mutagenesis.

Q60611	SATB1_MOUSE	DNA-binding protein SATB1	12692553	Tissue-specific nuclear architecture and gene expression regulated by SATB1.

Q5BCX8	EGLD_EMENI	Endo-beta-1,4-glucanase D	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

Q80WD0	R4RL1_RAT	Reticulon-4 receptor-like 1	12694398	Characterization of two novel proteins, NgRH1 and NgRH2, structurally and biochemically homologous to the Nogo-66 receptor.

O60704	TPST2_HUMAN	Protein-tyrosine sulfotransferase 2	9736702	Existence of distinct tyrosylprotein sulfotransferase genes: molecular characterization of tyrosylprotein sulfotransferase-2.

Q07914	TIM14_YEAST	Mitochondrial import inner membrane translocase subunit TIM14	14517234	Tim14, a novel key component of the import motor of the TIM23 protein translocase of mitochondria.

Q09796	KA111_SCHPO	Importin beta-like protein kap111	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P46962	CTK2_YEAST	CTD kinase subunit beta	9110987	Modulation of RNA polymerase II elongation efficiency by C-terminal heptapeptide repeat domain kinase I.

Q04958	NTE1_YEAST	Lysophospholipase NTE1	15044461	Neuropathy target esterase and its yeast homologue degrade phosphatidylcholine to glycerophosphocholine in living cells.

Q9UT45	ENG1_SCHPO	Endo-1,3(4)-beta-glucanase 1	12665550	The endo-beta-1,3-glucanase eng1p is required for dissolution of the primary septum during cell separation in Schizosaccharomyces pombe.

Q9NVU7	SDA1_HUMAN	Protein SDA1 homolog	11790298	Directed proteomic analysis of the human nucleolus.

P29037	TBP_MOUSE	TATA-box-binding protein	9050847	Cloning of murine RNA polymerase I-specific TAF factors: conserved interactions between the subunits of the species-specific transcription initiation factor TIF-IB/SL1.

P98171	RHG04_HUMAN	Rho GTPase-activating protein 4	8570618	An X chromosome-linked gene encoding a protein with characteristics of a rhoGAP predominantly expressed in hematopoietic cells.

Q06147	LCB5_YEAST	Sphingoid long chain base kinase 5	11278643	Calcium influx and signaling in yeast stimulated by intracellular sphingosine 1-phosphate accumulation.

O94536	UCP12_SCHPO	Putative ATP-dependent RNA helicase ucp12	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q20646	CEP1_CAEEL	Transcription factor cep-1	15242600	Structural differences in the DNA binding domains of human p53 and its C. elegans ortholog Cep-1.

P32266	MGM1_YEAST	Dynamin-like GTPase MGM1, mitochondrial	12707284	Processing of Mgm1 by the rhomboid-type protease Pcp1 is required for maintenance of mitochondrial morphology and of mitochondrial DNA.

B0BK72	MSP2_MARSO	Peroxidase 2	18038130	Novel peroxidases of Marasmius scorodonius degrade beta-carotene.

P20070	NB5R3_RAT	NADH-cytochrome b5 reductase 3	2391344	Molecular cloning of a cDNA encoding rat NADH-cytochrome b5 reductase and the corresponding gene.

Q8N6C5	IGSF1_HUMAN	Immunoglobulin superfamily member 1	12421765	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

P81122	IRS2_MOUSE	Insulin receptor substrate 2	11018022	Cloning and characterization of PHIP, a novel insulin receptor substrate-1 pleckstrin homology domain interacting protein.

Q10412	RSC58_SCHPO	Chromatin structure-remodeling complex subunit rsc58	18622392	Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast.

P49589	SYCC_HUMAN	Cysteinyl-tRNA synthetase, cytoplasmic	7987009	Nucleotide and deduced amino acid sequence of human cysteinyl-tRNA synthetase.

P76344	YODA_ECOLI	Metal-binding protein yodA	12480884	Regulation of yodA encoding a novel cadmium-induced protein in Escherichia coli.

P53853	VPS75_YEAST	Vacuolar protein sorting-associated protein 75	14562095	Global analysis of protein localization in budding yeast.

P22265	TSH_DROME	Protein teashirt	1360402	The role of the teashirt gene in trunk segmental identity in Drosophila.

O60504	VINEX_HUMAN	Vinexin	9885244	Vinexin: a novel vinculin-binding protein with multiple SH3 domains enhances actin cytoskeletal organization.

Q94BT6	ADO1_ARATH	Adagio protein 1	15447654	Formation of an SCF(ZTL) complex is required for proper regulation of circadian timing.

P59769	GRP78_ASPAW	78 kDa glucose-regulated protein homolog	9370263	The ER chaperone encoding bipA gene of black Aspergilli is induced by heat shock and unfolded proteins.

P97433	RGNEF_MOUSE	Rho-guanine nucleotide exchange factor	16236762	RNA-binding protein is involved in aggregation of light neurofilament protein and is implicated in the pathogenesis of motor neuron degeneration.

Q94FB9	AB1D_ARATH	ABC transporter D family member 1	12065405	Control of germination and lipid mobilization by COMATOSE, the Arabidopsis homologue of human ALDP.

Q9GYD9	CBP4B_DICDI	Calcium-binding protein 4b	10771103	Characterization and hetereologous expression of cDNAs encoding two novel closely related Ca(2+)-binding proteins in Dictyostelium discoideum.

Q7L1S5	CHST9_HUMAN	Carbohydrate sulfotransferase 9	11445554	Molecular cloning and expression of two distinct human N- acetylgalactosamine 4-O-sulfotransferases that transfer sulfate to GalNAc beta 1->4GlcNAc beta 1->R in both N- and O-glycans.

Q99P84	PLCE1_RAT	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon-1	16314422	G-protein-coupled receptor agonists activate endogenous phospholipase Cepsilon and phospholipase Cbeta3 in a temporally distinct manner.

P52172	SRP_DROME	Box A-binding factor	9012522	A molecular aspect of hematopoiesis and endoderm development common to vertebrates and Drosophila.

P97523	MET_RAT	Hepatocyte growth factor receptor	7628535	Modulation of hepatocyte growth factor and c-met in the rat mammary gland during pregnancy, lactation, and involution.

Q9QW30	NOTC2_RAT	Neurogenic locus notch homolog protein 2	1295745	Notch2: a second mammalian Notch gene.

Q811Q1	SMUG1_RAT	Single-strand selective monofunctional uracil-DNA glycosylase	12718543	Mammalian 5-formyluracil-DNA glycosylase. 2. Role of SMUG1 uracil-DNA glycosylase in repair of 5-formyluracil and other oxidized and deaminated base lesions.

P55809	SCOT1_HUMAN	Succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial	10964512	Succinyl-CoA:3-ketoacid CoA transferase (SCOT): cloning of the human SCOT gene, tertiary structural modeling of the human SCOT monomer, and characterization of three pathogenic mutations.

O49623	DPNP2_ARATH	SAL2 phosphatase	10205895	The Arabidopsis HAL2-like gene family includes a novel sodium- sensitive phosphatase.

P48482	PP12_ARATH	Serine/threonine-protein phosphatase PP1 isozyme 2	7678768	Expression of multiple type 1 phosphoprotein phosphatases in Arabidopsis thaliana.

Q9H9P2	CHODL_HUMAN	Chondrolectin	12079284	Molecular cloning and characterization of human chondrolectin, a novel type I transmembrane protein homologous to C-type lectins.

Q15858	SCN9A_HUMAN	Sodium channel protein type 9 subunit alpha	7720699	Structure and functional expression of a new member of the tetrodotoxin-sensitive voltage-activated sodium channel family from human neuroendocrine cells.

O59768	VCX1_SCHPO	Vacuolar calcium ion transporter	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8R216	SIRT4_MOUSE	NAD-dependent ADP-ribosyltransferase sirtuin-4	16959573	SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells.

P49775	HNT2_YEAST	Bis(5'-adenosyl)-triphosphatase	12028594	Control of dinucleoside polyphosphates by the FHIT-homologous HNT2 gene, adenine biosynthesis and heat shock in Saccharomyces cerevisiae.

P32942	ICAM3_HUMAN	Intercellular adhesion molecule 3	15728350	An atomic resolution view of ICAM recognition in a complex between the binding domains of ICAM-3 and integrin alphaLbeta2.

O04292	ATBH9_ARATH	Homeobox-leucine zipper protein ATHB-9	11395776	Role of PHABULOSA and PHAVOLUTA in determining radial patterning in shoots.

P51532	SMCA4_HUMAN	Transcription activator BRG1	12837248	The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome.

Q9FF86	DCR_ARATH	BAHD acyltransferase DCR	19828672	The Arabidopsis DCR encoding a soluble BAHD acyltransferase is required for cutin polyester formation and seed hydration properties.

P23786	CPT2_HUMAN	Carnitine O-palmitoyltransferase 2, mitochondrial	1988962	cDNA cloning, sequence analysis, and chromosomal localization of the gene for human carnitine palmitoyltransferase.

P83001	GSTE_PSEFL	Glutathione S-transferase	11900268	Occurence and properties of glutathione S-transferases in phenol- degrading Pseudomonas strains.

Q92794	MYST3_HUMAN	Histone acetyltransferase MYST3	11965546	MOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2.

Q13107	UBP4_HUMAN	Ubiquitin carboxyl-terminal hydrolase 4	16339847	The ubiquitin-specific protease Usp4 regulates the cell surface level of the A2A receptor.

P13521	SCG2_HUMAN	Secretogranin-2	2745426	The primary structure of human secretogranin II, a widespread tyrosine-sulfated secretory granule protein that exhibits low pH- and calcium-induced aggregation.

Q6T3U4	NPCL1_MOUSE	Niemann-Pick C1-like protein 1	14976318	Niemann-Pick C1 like 1 protein is critical for intestinal cholesterol absorption.

P20965	PABPA_XENLA	Polyadenylate-binding protein 1-A	16001084	The DAZL family proteins are PABP-binding proteins that regulate translation in germ cells.

P0AG96	SECE_ECOLI	Preprotein translocase subunit SecE	2673920	The secE gene encodes an integral membrane protein required for protein export in Escherichia coli.

Q9HC35	EMAL4_HUMAN	Echinoderm microtubule-associated protein-like 4	10995578	Cloning and localization of C2orf2(ropp120), a previously unknown WD repeat protein.

Q62739	RAB3I_RAT	Rab-3A-interacting protein	7532276	Interaction cloning of Rabin3, a novel protein that associates with the Ras-like GTPase Rab3A.

Q5YDB6	CPL1_ARATH	RNA polymerase II C-terminal domain phosphatase-like 1	18764923	CTD phosphatases in the attenuation of wound-induced transcription of jasmonic acid biosynthetic genes in Arabidopsis.

Q9SRY5	GST11_ARATH	Glutathione S-transferase 11	12090627	Probing the diversity of the Arabidopsis glutathione S-transferase gene family.

Q6UB35	C1TM_HUMAN	Monofunctional C1-tetrahydrofolate synthase, mitochondrial	16171773	Enzymatic characterization of human mitochondrial C1-tetrahydrofolate synthase.

P50897	PPT1_HUMAN	Palmitoyl-protein thioesterase 1	8816748	Lipid thioesters derived from acylated proteins accumulate in infantile neuronal ceroid lipofuscinosis: correction of the defect in lymphoblasts by recombinant palmitoyl-protein thioesterase.

P53848	FOL1_YEAST	Folic acid synthesis protein FOL1	15169867	Characterization of the Saccharomyces cerevisiae Fol1 protein: starvation for C1 carrier induces pseudohyphal growth.

Q9Y6N6	LAMC3_HUMAN	Laminin subunit gamma-3	10225960	Characterization and expression of the laminin gamma3 chain: a novel, non-basement membrane-associated, laminin chain.

Q06324	MMR1_YEAST	Mitochondrial MYO2 receptor-related protein 1	15201867	Mmr1p is a mitochondrial factor for Myo2p-dependent inheritance of mitochondria in the budding yeast.

Q9HBD1	RC3H2_HUMAN	RING finger and CCCH-type zinc finger domain-containing protein 2	10938276	A human gene coding for a membrane-associated nucleic acid-binding protein.

P21965	MCK1_YEAST	Protein kinase MCK1	1701015	Novel yeast protein kinase (YPK1 gene product) is a 40-kilodalton phosphotyrosyl protein associated with protein-tyrosine kinase activity.

Q9VCA8	ANKHM_DROME	Ankyrin repeat and KH domain-containing protein mask	11782402	MASK, a large ankyrin repeat and KH domain-containing protein involved in Drosophila receptor tyrosine kinase signaling.

P08879	NDKA_DROME	Nucleoside diphosphate kinase	7669763	Mechanism of phosphate transfer by nucleoside diphosphate kinase: X- ray structures of the phosphohistidine intermediate of the enzymes from Drosophila and Dictyostelium.

Q15796	SMAD2_HUMAN	Mothers against decapentaplegic homolog 2	9702198	Characterization of human FAST-1, a TGF beta and activin signal transducer.

Q16585	SGCB_HUMAN	Beta-sarcoglycan	8968749	Genomic screening for beta-sarcoglycan gene mutations: missense mutations may cause severe limb-girdle muscular dystrophy type 2E (LGMD 2E).

P16140	VATB_YEAST	V-type proton ATPase subunit B	2141385	Role of vacuolar acidification in protein sorting and zymogen activation: a genetic analysis of the yeast vacuolar proton- translocating ATPase.

P14625	ENPL_HUMAN	Endoplasmin	18264092	OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD.

P04157	PTPRC_RAT	Receptor-type tyrosine-protein phosphatase C	3158393	Evidence from cDNA clones that the rat leukocyte-common antigen (T200) spans the lipid bilayer and contains a cytoplasmic domain of 80,000 Mr.

P03999	OPSB_HUMAN	Blue-sensitive opsin	9089077	Sequences and evolution of human and squirrel monkey blue opsin genes.

Q9UKK6	NXT1_HUMAN	NTF2-related export protein 1	11583626	Structural basis for the recognition of a nucleoporin FG repeat by the NTF2-like domain of the TAP/p15 mRNA nuclear export factor.

P22413	ENPP1_HUMAN	Ectonucleotide pyrophosphatase/phosphodiesterase family member 1	1315502	Molecular cloning of cDNAs for human fibroblast nucleotide pyrophosphatase.

P31414	AVP1_ARATH	Pyrophosphate-energized vacuolar membrane proton pump 1	1311852	Molecular cloning and sequence of cDNA encoding the pyrophosphate- energized vacuolar membrane proton pump of Arabidopsis thaliana.

Q9V4K2	GR43A_DROME	Putative gustatory receptor 43a	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

Q5AU92	AGALC_EMENI	Alpha-galactosidase C	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

Q8BVL3	SNX17_MOUSE	Sorting nexin-17	12169628	The PX-domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptor.

Q99JL1	SPEF1_MOUSE	Sperm flagellar protein 1	15979255	Spef1, a conserved novel testis protein found in mouse sperm flagella.

P93655	LONM1_ARATH	Lon protease homolog 1, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q12297	TAF3_YEAST	Transcription initiation factor TFIID subunit 3	10788514	Identification of two novel TAF subunits of the yeast Saccharomyces cerevisiae TFIID complex.

Q9MAH0	CAPP1_ARATH	Phosphoenolpyruvate carboxylase 1	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

Q91ZW6	TMLH_RAT	Trimethyllysine dioxygenase, mitochondrial	11431483	Molecular and biochemical characterization of rat epsilon-N- trimethyllysine hydroxylase, the first enzyme of carnitine biosynthesis.

Q96EP0	RNF31_HUMAN	RING finger protein 31	20005846	Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction.

P47155	ILM1_YEAST	Protein ILM1	14562095	Global analysis of protein localization in budding yeast.

P62747	RHOB_RAT	Rho-related GTP-binding protein RhoB	1710770	The ras-related gene rhoB is an immediate-early gene inducible by v- Fps, epidermal growth factor, and platelet-derived growth factor in rat fibroblasts.

Q03195	RLI1_YEAST	Translation initiation factor RLI1	14562095	Global analysis of protein localization in budding yeast.

Q96BD5	PF21A_HUMAN	PHD finger protein 21A	15325272	Characterization of BHC80 in BRAF-HDAC complex, involved in neuron- specific gene repression.

Q13618	CUL3_HUMAN	Cullin-3	18573101	KCTD5, a putative substrate adaptor for cullin3 ubiquitin ligases.

P25583	KAR4_YEAST	Karyogamy protein KAR4	8754797	Kar4p, a karyogamy-specific component of the yeast pheromone response pathway.

Q13185	CBX3_HUMAN	Chromobox protein homolog 3	9636146	Interaction of SP100 with HP1 proteins: a link between the promyelocytic leukemia-associated nuclear bodies and the chromatin compartment.

P01769	HV308_HUMAN	Ig heavy chain V-III region GA	4208843	The switch point in mu heavy chains of human IgM immunoglobulins.

Q9H3J6	CL065_HUMAN	Probable peptide chain release factor C12orf65, mitochondrial	20186120	A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome.

Q9H2A7	CXL16_HUMAN	C-X-C motif chemokine 16	11290797	Expression cloning of the strl33/bonzo/tymstr ligand reveals elements of cc, cxc, and cx3c chemokines.

O43077	MDE3_SCHPO	Sporulation protein kinase mde3	10747048	Autoregulated expression of Schizosaccharomyces pombe meiosis- specific transcription factor Mei4 and a genome-wide search for its target genes.

Q6ZPK0	PF21A_MOUSE	PHD finger protein 21A	15325272	Characterization of BHC80 in BRAF-HDAC complex, involved in neuron- specific gene repression.

Q9V496	APLP_DROME	Apolipophorins	10393207	Heme-binding by Drosophila retinoid- and fatty acid-binding glycoprotein (RFABG), a member of the proapolipophorin gene family.

P53720	DUS2_YEAST	tRNA-dihydrouridine synthase 2	14562095	Global analysis of protein localization in budding yeast.

P42166	LAP2A_HUMAN	Lamina-associated polypeptide 2, isoform alpha	8530026	Structure and mapping of the human thymopoietin (TMPO) gene and relationship of human TMPO beta to rat lamin-associated polypeptide 2.

O13781	YEO3_SCHPO	Uncharacterized protein C17G6.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P08754	GNAI3_HUMAN	Guanine nucleotide-binding protein G(k) subunit alpha	2452165	Alpha i-3 cDNA encodes the alpha subunit of Gk, the stimulatory G protein of receptor-regulated K+ channels.

O88420	SCN8A_RAT	Sodium channel protein type 8 subunit alpha	9603190	Functional analysis of a voltage-gated sodium channel and its splice variant from rat dorsal root ganglia.

Q24478	CP190_DROME	Centrosome-associated zinc finger protein CP190	14996941	The Drosophila centrosome-associated protein CP190 is essential for viability but not for cell division.

P0A9P6	DEAD_ECOLI	Cold-shock DEAD box protein A	17259309	Mutational analysis of the Escherichia coli DEAD box protein CsdA.

P33760	PEX6_YEAST	Peroxisomal ATPase PEX6	16911527	Functional association of the AAA complex and the peroxisomal importomer.

Q96RU3	FNBP1_HUMAN	Formin-binding protein 1	15252009	A novel dynamin-associating molecule, formin-binding protein 17, induces tubular membrane invaginations and participates in endocytosis.

Q02846	GUC2D_HUMAN	Retinal guanylyl cyclase 1	9888789	Functional consequences of a rod outer segment membrane guanylate cyclase (ROS-GC1) gene mutation linked with Leber's congenital amaurosis.

Q9W534	MOODY_DROME	G-protein coupled receptor moody	16213219	moody encodes two GPCRs that regulate cocaine behaviors and blood- brain barrier permeability in Drosophila.

Q3UND0	SKAP2_MOUSE	Src kinase-associated phosphoprotein 2	11063873	Adaptor protein SKAP55R is associated with myeloid differentiation and growth arrest.

Q7Z7B1	PIGW_HUMAN	Phosphatidylinositol-glycan biosynthesis class W protein	14517336	PIG-W is critical for inositol acylation but not for flipping of glycosylphosphatidylinositol-anchor.

Q8BHK1	NIPA1_MOUSE	Magnesium transporter NIPA1	17166836	NIPA1(SPG6), the basis for autosomal dominant form of hereditary spastic paraplegia, encodes a functional Mg2+ transporter.

Q9ESK9	RBCC1_MOUSE	RB1-inducible coiled-coil protein 1	12095676	Isolation, characterization and mapping of the mouse and human RB1CC1 genes.

P36537	UDB10_HUMAN	UDP-glucuronosyltransferase 2B10	8333863	cDNA cloning and expression of two new members of the human liver UDP-glucuronosyltransferase 2B subfamily.

P27986	P85A_HUMAN	Phosphatidylinositol 3-kinase regulatory subunit alpha	7537849	Phosphotyrosine-dependent interaction of SHC and insulin receptor substrate 1 with the NPEY motif of the insulin receptor via a novel non-SH2 domain.

P08173	ACM4_HUMAN	Muscarinic acetylcholine receptor M4	3037705	Identification of a family of muscarinic acetylcholine receptor genes.

Q9GZX6	IL22_HUMAN	Interleukin-22	10875937	Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R.

P59826	LPLC3_HUMAN	Long palate, lung and nasal epithelium carcinoma-associated protein 3	11971875	PLUNC: a novel family of candidate host defence proteins expressed in the upper airways and nasopharynx.

P33309	DOM34_YEAST	Protein DOM34	17889667	Structural and functional insights into Dom34, a key component of no- go mRNA decay.

Q8R0W0	EPIPL_MOUSE	Epiplakin	12791695	Epiplakin gene analysis in mouse reveals a single exon encoding a 725-kDa protein with expression restricted to epithelial tissues.

P54824	DDX6_XENLA	ATP-dependent RNA helicase ddx6	17942399	CPEB interacts with an ovary-specific eIF4E and 4E-T in early Xenopus oocytes.

O94488	MBO1_SCHPO	Microtubule organizer protein 1	15004232	Identification and characterization of two novel proteins affecting fission yeast gamma-tubulin complex function.

P0A921	PA1_ECOLI	Phospholipase A1	11371166	Structural investigations of calcium binding and its role in activity and activation of outer membrane phospholipase A from Escherichia coli.

Q95NM6	NUCG_CAEEL	Endonuclease G, mitochondrial	11452313	Mitochondrial endonuclease G is important for apoptosis in C. elegans.

Q9BUX1	CHAC1_HUMAN	Cation transport regulator-like protein 1	19109178	CHAC1/MGC4504 is a novel proapoptotic component of the unfolded protein response, downstream of the ATF4-ATF3-CHOP cascade.

O18276	GBRB_CAEEL	Gamma-aminobutyric acid receptor subunit beta	12421359	Study of the nematode putative GABA type-A receptor subunits: evidence for modulation by ivermectin.

P48552	NRIP1_HUMAN	Nuclear receptor-interacting protein 1	10364267	Receptor interacting protein RIP140 inhibits both positive and negative gene regulation by glucocorticoids.

Q9NSC5	HOME3_HUMAN	Homer protein homolog 3	9808458	Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins.

P12689	REV1_YEAST	DNA repair protein REV1	8751446	Deoxycytidyl transferase activity of yeast REV1 protein.

P81916	OR33C_DROME	Odorant receptor 33c	10458908	Identification of candidate Drosophila olfactory receptors from genomic DNA sequence.

Q8MT08	GAS8_DROME	Growth arrest-specific protein 8 homolog	11751847	Isolation and properties of Gas8, a growth arrest-specific gene regulated during male gametogenesis to produce a protein associated with the sperm motility apparatus.

Q9VPW1	ASTE_DROME	Protein asteroid	9644838	The Drosophila gene asteroid encodes a novel protein and displays dosage-sensitive interactions with Star and Egfr.

P13010	XRCC5_HUMAN	X-ray repair cross-complementing protein 5	11493912	Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair.

O08625	SYT10_RAT	Synaptotagmin-10	9122248	A novel seizure-induced synaptotagmin gene identified by differential display.

P23511	NFYA_HUMAN	Nuclear transcription factor Y subunit alpha	2000400	A cDNA encoding a human CCAAT-binding protein cloned by functional complementation in yeast.

O60244	MED14_HUMAN	Mediator of RNA polymerase II transcription subunit 14	12218053	A coregulatory role for the TRAP-mediator complex in androgen receptor-mediated gene expression.

P38993	FET3_YEAST	Iron transport multicopper oxidase FET3	9722559	Spectral and kinetic properties of the Fet3 protein from Saccharomyces cerevisiae, a multinuclear copper ferroxidase enzyme.

Q14641	INSL4_HUMAN	Early placenta insulin-like peptide	8666396	Cloning of a new member of the insulin gene superfamily (INSL4) expressed in human placenta.

O74381	POF9_SCHPO	F-box protein pof9	15147268	Molecular interactions of fission yeast Skp1 and its role in the DNA damage checkpoint.

P33226	TORC_ECOLI	Cytochrome c-type protein torC	8022286	TMAO anaerobic respiration in Escherichia coli: involvement of the tor operon.

P70500	CDIPT_RAT	CDP-diacylglycerol--inositol 3-phosphatidyltransferase	7998949	Identification of rat liver phosphatidylinositol synthase as a 21 kDa protein.

P49793	NUP98_RAT	Nuclear pore complex protein Nup98	7736573	The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex.

P43088	PF2R_HUMAN	Prostaglandin F2-alpha receptor	8300593	Cloning and expression of a cDNA for the human prostanoid FP receptor.

Q9UN42	AT1B4_HUMAN	Protein ATP1B4	10456317	Identification of a novel gene of the X,K-ATPase beta-subunit family that is predominantly expressed in skeletal and heart muscles.

Q8IYM1	SEP12_HUMAN	Septin-12	18047794	SEPT12 interacts with SEPT6 and this interaction alters the filament structure of SEPT6 in Hela cells.

O75817	POP7_HUMAN	Ribonuclease P protein subunit p20	9630247	Autoantigenic properties of some protein subunits of catalytically active complexes of human ribonuclease P.

P22057	PTGDS_RAT	Prostaglandin-H2 D-isomerase	8815894	Lipocalin-type prostaglandin D synthase (beta-trace) is located in pigment epithelial cells of rat retina and accumulates within interphotoreceptor matrix.

Q12483	SNF8_YEAST	Vacuolar-sorting protein SNF8	12194858	Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular body.

Q1MTN7	RPM1_SCHPO	Exoribonuclease II, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O60239	3BP5_HUMAN	SH3 domain-binding protein 5	9571151	Identification and characterization of a novel SH3-domain binding protein, Sab, which preferentially associates with Bruton's tyrosine kinase (Btk).

O00311	CDC7_HUMAN	Cell division cycle 7-related protein kinase	9250678	Human and Xenopus cDNAs encoding budding yeast Cdc7-related kinases: in vitro phosphorylation of MCM subunits by a putative human homologue of Cdc7.

P41805	RL10_YEAST	60S ribosomal protein L10	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q9VCR6	SAV_DROME	Scaffold protein salvador	12421711	Shar-pei mediates cell proliferation arrest during imaginal disc growth in Drosophila.

Q99MZ3	WBS14_MOUSE	Williams-Beuren syndrome chromosomal region 14 protein homolog	11230181	WBSCR14, a gene mapping to the Williams-Beuren syndrome deleted region, is a new member of the Mlx transcription factor network.

P02708	ACHA_HUMAN	Acetylcholine receptor subunit alpha	8872460	New mutations in acetylcholine receptor subunit genes reveal heterogeneity in the slow-channel congenital myasthenic syndrome.

Q9ZR12	GRH1_ARATH	GRR1-like protein 1	15992545	Plant development is regulated by a family of auxin receptor F box proteins.

Q70Z35	PREX2_HUMAN	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein	15304343	P-Rex2, a new guanine-nucleotide exchange factor for Rac.

Q09845	GPD2_SCHPO	Glycerol-3-phosphate dehydrogenase [NAD+] 2	8825100	Osmoregulation of fission yeast: cloning of two distinct genes encoding glycerol-3-phosphate dehydrogenase, one of which is responsible for osmotolerance for growth.

P53859	CSL4_YEAST	Exosome complex component CSL4	10465791	The yeast exosome and human PM-Scl are related complexes of 3'-->5' exonucleases.

Q9H4B7	TBB1_HUMAN	Tubulin beta-1 chain	18849486	Mutation of the beta1-tubulin gene associated with congenital macrothrombocytopenia affecting microtubule assembly.

P16143	PO2F1_XENLA	POU domain, class 2, transcription factor 1	2017364	Xenopus laevis Oct-1 does not bind to certain histone H2B gene promoter octamer motifs for which a novel octamer-binding factor has high affinity.

Q8K4J6	MKL1_MOUSE	MKL/myocardin-like protein 1	12019265	Identification of a novel transcriptional activator, BSAC, by a functional cloning to inhibit tumor necrosis factor-induced cell death.

Q61164	CTCF_MOUSE	Transcriptional repressor CTCF	11743158	CTCF, a candidate trans-acting factor for X-inactivation choice.

Q08412	CUE5_YEAST	Ubiquitin-binding protein CUE5	14562095	Global analysis of protein localization in budding yeast.

P77348	MPPA_ECOLI	Periplasmic murein peptide-binding protein	9495761	MppA, a periplasmic binding protein essential for import of the bacterial cell wall peptide L-alanyl-gamma-D-glutamyl-meso- diaminopimelate.

P87060	POP1_SCHPO	WD repeat-containing protein pop1	10209119	F-box/WD-repeat proteins pop1p and Sud1p/Pop2p form complexes that bind and direct the proteolysis of cdc18p.

Q21341	LET99_CAEEL	Protein let-99	14534135	LET-99 opposes Galpha/GPR signaling to generate asymmetry for spindle positioning in response to PAR and MES-1/SRC-1 signaling.

Q9NXR1	NDE1_HUMAN	Nuclear distribution protein nudE homolog 1	17600710	Cenp-F links kinetochores to Ndel1/Nde1/Lis1/dynein microtubule motor complexes.

P11373	CUTI1_COLGL	Cutinase 1	17043825	Purification and identification of cutinases from Colletotrichum kahawae and Colletotrichum gloeosporioides.

P28319	CWP1_YEAST	Cell wall protein CWP1	16672383	Role of cell cycle-regulated expression in the localized incorporation of cell wall proteins in yeast.

Q9P7R8	YHV3_SCHPO	Uncharacterized protein C211.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q06449	PIN3_YEAST	[PSI+] inducibility protein 3	10512884	The Saccharomyces cerevisiae homologue of human Wiskott-Aldrich syndrome protein Las17p interacts with the Arp2/3 complex.

Q02792	XRN2_YEAST	5'-3' exoribonuclease 2	11030620	Identification of a regulated pathway for nuclear pre-mRNA turnover.

P0A9I8	NIRD_ECOLI	Nitrite reductase [NAD(P)H] small subunit	1435259	Transcriptional control, translation and function of the products of the five open reading frames of the Escherichia coli nir operon.

Q12402	YOP1_YEAST	Protein YOP1	12427979	Function of a plant stress-induced gene, HVA22. Synthetic enhancement screen with its yeast homolog reveals its role in vesicular traffic.

Q9SLH0	EIL1_ARATH	ETHYLENE INSENSITIVE 3-like 1 protein	9215635	Activation of the ethylene gas response pathway in Arabidopsis by the nuclear protein ETHYLENE-INSENSITIVE3 and related proteins.

P48165	CXA8_HUMAN	Gap junction alpha-8 protein	7796604	The human lens intrinsic membrane protein MP70 (Cx50) gene: clonal analysis and chromosome mapping.

P38828	LSM12_YEAST	Protein LSM12	14562095	Global analysis of protein localization in budding yeast.

Q9SJ56	BLH1_ARATH	BEL1-like homeodomain protein 1	17873098	The Arabidopsis BEL1-LIKE HOMEODOMAIN proteins SAW1 and SAW2 act redundantly to regulate KNOX expression spatially in leaf margins.

Q9W568	HFW1_DROME	Protein halfway	15189568	Molecular characterization of the singed wings locus of Drosophila melanogaster.

Q07092	COGA1_HUMAN	Collagen alpha-1(XVI) chain	15165854	Molecular structure and interaction of recombinant human type XVI collagen.

P36006	MYO3_YEAST	Myosin-3	11901111	The novel adaptor protein, Mti1p, and Vrp1p, a homolog of Wiskott- Aldrich syndrome protein-interacting protein (WIP), may antagonistically regulate type I myosins in Saccharomyces cerevisiae.

Q8UVJ6	VANG2_DANRE	Vang-like protein 2	10996075	Somites in zebrafish doubly mutant for knypek and trilobite form without internal mesenchymal cells or compaction.

Q20646	CEP1_CAEEL	Transcription factor cep-1	15605074	C. elegans ced-13 can promote apoptosis and is induced in response to DNA damage.

P43254	COP1_ARATH	E3 ubiquitin-protein ligase COP1	12023303	Two interacting bZIP proteins are direct targets of COP1-mediated control of light-dependent gene expression in Arabidopsis.

P43639	CSK2B_YEAST	Casein kinase II subunit beta	8135547	Casein kinase II of Saccharomyces cerevisiae contains two distinct regulatory subunits, beta and beta'.

P40902	ISP7_SCHPO	Sexual differentiation process protein isp7	7954893	Identification and characterization of genes induced during sexual differentiation in Schizosaccharomyces pombe.

Q99463	NPY6R_HUMAN	Putative neuropeptide Y receptor type 6	8910373	Molecular characterization of a second mouse pancreatic polypeptide receptor and its inactivated human homologue.

P20807	CAN3_HUMAN	Calpain-3	7720071	Mutations in the proteolytic enzyme calpain 3 cause limb-girdle muscular dystrophy type 2A.

P26432	SL9A3_RABIT	Sodium/hydrogen exchanger 3	19088451	Elevated intracellular calcium stimulates NHE3 activity by an IKEPP (NHERF4) dependent mechanism.

C0LGU0	RLK_ARATH	Probable LRR receptor-like serine/threonine-protein kinase RLK	18591430	Rho-GTPase-dependent filamentous actin dynamics coordinate vesicle targeting and exocytosis during tip growth.

Q9EQV8	CBPN_RAT	Carboxypeptidase N catalytic chain	11021404	Molecular cloning and partial characterization of rat procarboxypeptidase R and carboxypeptidase N.

Q8TDC3	BRSK1_HUMAN	BR serine/threonine-protein kinase 1	15150265	Human SAD1 kinase is involved in UV-induced DNA damage checkpoint function.

P06759	APOC3_RAT	Apolipoprotein C-III	3020028	Linkage, evolution, and expression of the rat apolipoprotein A-I, C- III, and A-IV genes.

Q8WV24	PHLA1_HUMAN	Pleckstrin homology-like domain family A member 1	11369516	Inhibition of protein synthesis by the T cell receptor-inducible human TDAG51 gene product.

A2AC93	DNAI2_MOUSE	Dynein intermediate chain 2, axonemal	19052621	Ktu/PF13 is required for cytoplasmic pre-assembly of axonemal dyneins.

Q04863	RELB_MOUSE	Transcription factor RelB	11931770	Peptide-induced negative selection of thymocytes activates transcription of an NF-kappa B inhibitor.

P36776	LONM_HUMAN	Lon protease homolog, mitochondrial	12198491	Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism.

Q9Z1S0	BUB1B_MOUSE	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta	12925705	Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss.

P83191	PS4_PSEPD	Pseudin-4	11689009	Pseudin-2: an antimicrobial peptide with low hemolytic activity from the skin of the paradoxical frog.

P42003	MAD_DROME	Protein mothers against dpp	12754252	DSmurf selectively degrades decapentaplegic-activated MAD, and its overexpression disrupts imaginal disc development.

A9ZSY3	TRET1_BOMMO	Facilitated trehalose transporter Tret1	20035867	The trehalose transporter 1 gene sequence is conserved in insects and encodes proteins with different kinetic properties involved in trehalose import into peripheral tissues.

Q9JME2	CHSTB_MOUSE	Carbohydrate sulfotransferase 11	10722746	Molecular cloning and expression of chondroitin 4-sulfotransferase.

Q9UI12	VATH_HUMAN	V-type proton ATPase subunit H	12032142	Subunit H of the V-ATPase binds to the medium chain of adaptor protein complex 2 and connects Nef to the endocytic machinery.

Q9QW08	PHOS_MOUSE	Phosducin	8224906	The sequence of the mouse phosducin-encoding gene and its 5'-flanking region.

Q01534	TSPY1_HUMAN	Testis-specific Y-encoded protein 1	1284595	Molecular isolation and characterization of an expressed gene from the human Y chromosome.

Q9UJT0	TBE_HUMAN	Tubulin epsilon chain	10620804	Delta-tubulin and epsilon-tubulin: two new human centrosomal tubulins reveal new aspects of centrosome structure and function.

O60828	PQBP1_HUMAN	Polyglutamine-binding protein 1	10198427	Npw38, a novel nuclear protein possessing a WW domain capable of activating basal transcription.

Q01085	TIAR_HUMAN	Nucleolysin TIAR	1326761	Identification and functional characterization of a TIA-1-related nucleolysin.

Q9H0H5	RGAP1_HUMAN	Rac GTPase-activating protein 1	11278976	Tat1, a novel sulfate transporter specifically expressed in human male germ cells and potentially linked to rhogtpase signaling.

Q15814	TBCC_HUMAN	Tubulin-specific chaperone C	8706133	Pathway leading to correctly folded beta-tubulin.

O13905	YF3E_SCHPO	BSD domain-containing protein C22A12.14c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q6DD88	ATLA3_HUMAN	Atlastin-3	19665976	A class of dynamin-like GTPases involved in the generation of the tubular ER network.

Q9UBB5	MBD2_HUMAN	Methyl-CpG-binding domain protein 2	9774669	Identification and characterization of a family of mammalian methyl- CpG binding proteins.

Q9BZM1	PG12A_HUMAN	Group XIIA secretory phospholipase A2	11031251	Cloning and recombinant expression of a structurally novel human secreted phospholipase A2.

P0AA84	YBHO_ECOLI	Putative cardiolipin synthase ybhO	10634942	A second Escherichia coli protein with CL synthase activity.

P31977	EZRI_RAT	Ezrin	11457882	Loss of glomerular foot processes is associated with uncoupling of podocalyxin from the actin cytoskeleton.

Q9JLI3	MMEL1_MOUSE	Membrane metallo-endopeptidase-like 1	10542292	Molecular identification and characterization of novel membrane-bound metalloprotease, the soluble secreted form of which hydrolyzes a variety of vasoactive peptides.

P93026	VSR1_ARATH	Vacuolar-sorting receptor 1	10871276	The plant vacuolar sorting receptor AtELP is involved in transport of NH(2)-terminal propeptide-containing vacuolar proteins in Arabidopsis thaliana.

P55283	CADH4_HUMAN	Cadherin-4	2059658	Diversity of the cadherin family: evidence for eight new cadherins in nervous tissue.

Q9UTK9	YIVH_SCHPO	Putative 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase C144.17c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q54XQ2	RCKA_DICDI	RGS domain-containing serine/threonine-protein kinase A	12686622	A regulator of G protein signaling-containing kinase is important for chemotaxis and multicellular development in dictyostelium.

Q7L576	CYFP1_HUMAN	Cytoplasmic FMR1-interacting protein 1	16260607	CRMP-2 is involved in kinesin-1-dependent transport of the Sra- 1/WAVE1 complex and axon formation.

Q9NYQ6	CELR1_HUMAN	Cadherin EGF LAG seven-pass G-type receptor 1	10716726	Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.

Q13905	RPGF1_HUMAN	Rap guanine nucleotide exchange factor 1	7806500	Four proline-rich sequences of the guanine-nucleotide exchange factor C3G bind with unique specificity to the first Src homology 3 domain of Crk.

Q9YGK8	IRX1A_XENLA	Iroquois-class homeodomain protein irx-1-A	12385755	Xiro homeoproteins coordinate cell cycle exit and primary neuron formation by upregulating neuronal-fate repressors and downregulating the cell-cycle inhibitor XGadd45-gamma.

Q9ULW0	TPX2_HUMAN	Targeting protein for Xklp2	18662907	Modulation of kinase-inhibitor interactions by auxiliary protein binding: crystallography studies on Aurora A interactions with VX-680 and with TPX2.

P15374	UCHL3_HUMAN	Ubiquitin carboxyl-terminal hydrolase isozyme L3	2530630	The neuron-specific protein PGP 9.5 is a ubiquitin carboxyl-terminal hydrolase.

P53172	SDS23_YEAST	Protein SDS23	16041152	Functional conservation between fission yeast moc1/sds23 and its two orthologs, budding yeast SDS23 and SDS24, and phenotypic differences in their disruptants.

P02452	CO1A1_HUMAN	Collagen alpha-1(I) chain	14749390	TRAM2 protein interacts with endoplasmic reticulum Ca2+ pump Serca2b and is necessary for collagen type I synthesis.

P27169	PON1_HUMAN	Serum paraoxonase/arylesterase 1	7638166	Reconsideration of the catalytic center and mechanism of mammalian paraoxonase/arylesterase.

Q8CHT1	NGEF_MOUSE	Ephexin-1	10777665	Characterization of Ngef, a novel member of the Dbl family of genes expressed predominantly in the caudate nucleus.

P15976	GATA1_HUMAN	Erythroid transcription factor	2300555	The major human erythroid DNA-binding protein (GF-1): primary sequence and localization of the gene to the X chromosome.

P11831	SRF_HUMAN	Serum response factor	3203386	Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum response element.

Q8IU60	DCP2_HUMAN	mRNA-decapping enzyme 2	18172165	Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'.

Q9NDJ2	DOM_DROME	Helicase domino	11262242	The domino gene of Drosophila encodes novel members of the SWI2/SNF2 family of DNA-dependent ATPases, which contribute to the silencing of homeotic genes.

Q10137	SEC14_SCHPO	Sec14 cytosolic factor	11294895	The Schizosaccharomyces pombe spo20(+) gene encoding a homologue of Saccharomyces cerevisiae Sec14 plays an important role in forespore membrane formation.

P42685	FRK_HUMAN	Tyrosine-protein kinase FRK	19345329	Rak functions as a tumor suppressor by regulating PTEN protein stability and function.

Q5BPS3	DOR_ARATH	F-box protein DOR	18835996	F-box protein DOR functions as a novel inhibitory factor for abscisic acid-induced stomatal closure under drought stress in Arabidopsis.

Q9V4Z9	LINES_DROME	Protein lines	12117814	Drumstick is a zinc finger protein that antagonizes Lines to control patterning and morphogenesis of the Drosophila hindgut.

Q55EX9	Y8948_DICDI	Putative methyltransferase DDB_G0268948	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q1HFS8	EGLB_EMENI	Endo-beta-1,4-glucanase B	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

Q9LW56	FAO3_ARATH	Long-chain-alcohol oxidase FAO3	15358540	Functional identification of AtFao3, a membrane bound long chain alcohol oxidase in Arabidopsis thaliana.

Q9NDM2	GUTR1_DROME	Gustatory receptor trehalose 1	10884225	Molecular identification of a taste receptor gene for trehalose in Drosophila.

Q9AMK8	RL2_STRCU	50S ribosomal protein L2	9299515	Protein kinase associated with ribosomes phosphorylates ribosomal proteins of Streptomyces collinus.

Q05580	YD266_YEAST	LIM domain and RING finger protein YDR266C	14562095	Global analysis of protein localization in budding yeast.

Q01909	ATPG2_ARATH	ATP synthase gamma chain 2, chloroplastic	1826905	Two genes, atpC1 and atpC2, for the gamma subunit of Arabidopsis thaliana chloroplast ATP synthase.

O14964	HGS_HUMAN	Hepatocyte growth factor-regulated tyrosine kinase substrate	18675823	Hypertonia-associated protein Trak1 is a novel regulator of endosome- to-lysosome trafficking.

P18054	LOX12_HUMAN	Arachidonate 12-lipoxygenase, 12S-type	2377602	Molecular cloning, primary structure, and expression of the human platelet/erythroleukemia cell 12-lipoxygenase.

Q6PER3	MARE3_MOUSE	Microtubule-associated protein RP/EB family member 3	17310996	p53 downstream target DDA3 is a novel microtubule-associated protein that interacts with end-binding protein EB3 and activates beta-catenin pathway.

Q8N0W4	NLGNX_HUMAN	Neuroligin-4, X-linked	12669065	Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism.

Q02930	CREB5_HUMAN	Cyclic AMP-responsive element-binding protein 5	8378084	Regulation of trans-activating capacity of CRE-BPa by phorbol ester tumor promoter TPA.

P55072	TERA_HUMAN	Transitional endoplasmic reticulum ATPase	18656546	Ubxd1 is a novel co-factor of the human p97 ATPase.

O54753	H17B6_RAT	17-beta-hydroxysteroid dehydrogenase type 6	9188497	Expression cloning and characterization of oxidative 17beta- and 3alpha-hydroxysteroid dehydrogenases from rat and human prostate.

Q8N392	RHG18_HUMAN	Rho GTPase-activating protein 18	15231747	A protein interaction framework for human mRNA degradation.

Q62764	DBPA_RAT	DNA-binding protein A	8029009	A novel growth-inducible gene that encodes a protein with a conserved cold-shock domain.

Q570C0	TIR1_ARATH	Protein TRANSPORT INHIBITOR RESPONSE 1	17410169	Mechanism of auxin perception by the TIR1 ubiquitin ligase.

Q9S775	PKL_ARATH	CHD3-type chromatin-remodeling factor PICKLE	16359393	PICKLE acts during germination to repress expression of embryonic traits.

P29387	GBB4_MOUSE	Guanine nucleotide-binding protein subunit beta-4	1543505	Diversity among the beta subunits of heterotrimeric GTP-binding proteins: characterization of a novel beta-subunit cDNA.

Q06250	WIT1_HUMAN	Wilms tumor-associated protein	2173145	Tissue, developmental, and tumor-specific expression of divergent transcripts in Wilms tumor.

Q62190	RON_MOUSE	Macrophage-stimulating protein receptor	10508511	Fv2 encodes a truncated form of the Stk receptor tyrosine kinase.

Q54JL7	CNRN_DICDI	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase cnrN	18676953	A protein with similarity to PTEN regulates aggregation territory size by decreasing cyclic AMP pulse size during Dictyostelium discoideum development.

P93004	PIP27_ARATH	Aquaporin PIP2-7	9276952	The major intrinsic protein family of Arabidopsis has 23 members that form three distinct groups with functional aquaporins in each group.

P53350	PLK1_HUMAN	Serine/threonine-protein kinase PLK1	18521620	Plk1 regulates mitotic Aurora A function through betaTrCP-dependent degradation of hBora.

O42927	YBD3_SCHPO	Uncharacterized protein C16C6.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UTC3	PSF3_SCHPO	DNA replication complex GINS protein psf3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8NDV2	GPR26_HUMAN	G-protein coupled receptor 26	17363172	Tissue distribution and functional analyses of the constitutively active orphan G protein coupled receptors, GPR26 and GPR78.

Q8R4R9	PP14C_RAT	Protein phosphatase 1 regulatory subunit 14C	11812771	KEPI, a PKC-dependent protein phosphatase 1 inhibitor regulated by morphine.

P52949	HXA5_RAT	Homeobox protein Hox-A5	7915120	Cloning and sequence analysis of homeobox transcription factor cDNAs with an inosine-containing probe.

Q99N48	SYTL3_MOUSE	Synaptotagmin-like protein 3	11327731	Novel splicing isoforms of synaptotagmin-like proteins 2 and 3: identification of the Slp homology domain.

Q9LVQ0	PME31_ARATH	Pectinesterase 31	18936961	Activity of an atypical Arabidopsis thaliana pectin methylesterase.

P0ABF1	PCNB_ECOLI	Poly(A) polymerase	1438224	Identification of the gene for an Escherichia coli poly(A) polymerase.

P23512	FOXA1_RAT	Hepatocyte nuclear factor 3-alpha	2227418	HNF-3A, a hepatocyte-enriched transcription factor of novel structure is regulated transcriptionally.

P35207	SKI2_YEAST	Antiviral helicase SKI2	10744028	The yeast antiviral proteins Ski2p, Ski3p, and Ski8p exist as a complex in vivo.

P30189	TOP1_DROME	DNA topoisomerase 1	1335568	Isolation and characterization of a gene encoding DNA topoisomerase I in Drosophila melanogaster.

P37176	EGLN_PIG	Endoglin	8294451	Endoglin forms a heteromeric complex with the signaling receptors for transforming growth factor-beta.

P32830	TIM12_YEAST	Mitochondrial import inner membrane translocase subunit TIM12	9430585	Import of mitochondrial carriers mediated by essential proteins of the intermembrane space.

P83519	LECG_BOTJR	Galactose-specific lectin	10628348	The effect of a lectin from the venom of the snake, Bothrops jararacussu, on tumor cell proliferation.

Q9FHQ3	HS157_ARATH	15.7 kDa heat shock protein, peroxisomal	16531488	Identification and characterization of a stress-inducible and a constitutive small heat-shock protein targeted to the matrix of plant peroxisomes.

O43293	DAPK3_HUMAN	Death-associated protein kinase 3	12917339	ZIP kinase triggers apoptosis from nuclear PML oncogenic domains.

P70560	COCA1_RAT	Collagen alpha-1(XII) chain	10419532	Structural variation of type XII collagen at its carboxyl-terminal NC1 domain generated by tissue-specific alternative splicing.

Q04149	MUS81_YEAST	Crossover junction endonuclease MUS81	10905349	MUS81 encodes a novel helix-hairpin-helix protein involved in the response to UV- and methylation-induced DNA damage in Saccharomyces cerevisiae.

Q06696	VPS36_YEAST	Vacuolar protein-sorting-associated protein 36	15029239	Ubiquitin interactions of NZF zinc fingers.

P10721	KIT_HUMAN	Mast/stem cell growth factor receptor	9990072	Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosis.

Q45VK7	DYHC2_MOUSE	Cytoplasmic dynein 2 heavy chain 1	16229832	Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli.

P11511	CP19A_HUMAN	Cytochrome P450 19A1	2848247	Isolation of a full-length cDNA insert encoding human aromatase system cytochrome P-450 and its expression in nonsteroidogenic cells.

Q9M5K2	DLDH2_ARATH	Dihydrolipoyl dehydrogenase 2, mitochondrial	11598235	Characterization of two cDNAs encoding mitochondrial lipoamide dehydrogenase from Arabidopsis.

P13688	CEAM1_HUMAN	Carcinoembryonic antigen-related cell adhesion molecule 1	2457922	Molecular cloning of a cDNA coding biliary glycoprotein I: primary structure of a glycoprotein immunologically crossreactive with carcinoembryonic antigen.

O88397	SO1A5_RAT	Solute carrier organic anion transporter family member 1A5	9712861	Molecular characterization and tissue distribution of a new organic anion transporter subtype (oatp3) that transports thyroid hormones and taurocholate and comparison with oatp2.

Q9NP98	MYOZ1_HUMAN	Myozenin-1	11842093	Calsarcin-3, a novel skeletal muscle-specific member of the calsarcin family, interacts with multiple Z-disc proteins.

P38270	ATG14_YEAST	Autophagy-related protein 14	9712845	Apg14p and Apg6/Vps30p form a protein complex essential for autophagy in the yeast, Saccharomyces cerevisiae.

Q9D8I1	PERP1_MOUSE	Plasma cell-induced resident endoplasmic reticulum protein	19805154	Efficient IgM assembly and secretion require the plasma cell induced endoplasmic reticulum protein pERp1.

P34220	YBF5_YEAST	Deoxyribonuclease Tat-D	15657035	Search for apoptotic nucleases in yeast: role of Tat-D nuclease in apoptotic DNA degradation.

O01501	CCNE_CAEEL	G1/S-specific cyclin-E	12606285	Cyclin E expression during development in Caenorhabditis elegans.

P84265	DAH42_LITDA	Dahlein-4.2	11555873	Bioactive dahlein peptides from the skin secretions of the Australian aquatic frog Litoria dahlii: sequence determination by electrospray mass spectrometry.

P32796	CACP_YEAST	Carnitine O-acetyltransferase, mitochondrial	8420957	Cloning and sequencing of a cDNA encoding Saccharomyces cerevisiae carnitine acetyltransferase. Use of the cDNA in gene disruption studies.

Q02318	CP27A_HUMAN	Sterol 26-hydroxylase, mitochondrial	1708392	Characterization of human sterol 27-hydroxylase. A mitochondrial cytochrome P-450 that catalyzes multiple oxidation reaction in bile acid biosynthesis.

Q12382	DGK1_YEAST	CTP-dependent diacylglycerol kinase 1	18458076	Characterization of the yeast DGK1-encoded CTP-dependent diacylglycerol kinase.

Q9Y2W2	WBP11_HUMAN	WW domain-binding protein 11	10593949	Association of two nuclear proteins, Npw38 and NpwBP, via the interaction between the WW domain and a novel proline-rich motif containing glycine and arginine.

Q80U87	UBP8_MOUSE	Ubiquitin carboxyl-terminal hydrolase 8	15314180	Stabilization of the E3 ubiquitin ligase Nrdp1 by the deubiquitinating enzyme USP8.

P38398	BRCA1_HUMAN	Breast cancer type 1 susceptibility protein	11877377	SMC1 is a downstream effector in the ATM/NBS1 branch of the human S- phase checkpoint.

Q9UGL1	KDM5B_HUMAN	Lysine-specific demethylase 5B	10336460	A novel gene (PLU-1) containing highly conserved putative DNA/chromatin binding motifs is specifically up-regulated in breast cancer.

P28325	CYTD_HUMAN	Cystatin-D	1939105	Structure and expression of the gene encoding cystatin D, a novel human cysteine proteinase inhibitor.

Q9FGY1	BXL1_ARATH	Beta-D-xylosidase 1	19458117	AtBXL1 encodes a bifunctional beta-D-xylosidase/alpha-L- arabinofuranosidase required for pectic arabinan modification in arabidopsis mucilage secretory cells.

Q9Y6L6	SO1B1_HUMAN	Solute carrier organic anion transporter family member 1B1	10358072	Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1.

P77202	DSBG_ECOLI	Thiol:disulfide interchange protein DsbG	19965429	A periplasmic reducing system protects single cysteine residues from oxidation.

P23978	SC6A1_RAT	Sodium- and chloride-dependent GABA transporter 1	1975955	Cloning and expression of a rat brain GABA transporter.

P08911	ACM5_RAT	Muscarinic acetylcholine receptor M5	2540186	Molecular cloning and expression of a fifth muscarinic acetylcholine receptor.

Q9XTY6	NUMB1_CAEEL	Numb-related protein 1	11134025	Structural properties and mechanisms that govern association of C kinase adapter 1 with protein kinase C3 and the cell periphery.

P11511	CP19A_HUMAN	Cytochrome P450 19A1	19129847	Structural basis for androgen specificity and oestrogen synthesis in human aromatase.

O75695	XRP2_HUMAN	Protein XRP2	9697692	Positional cloning of the gene for X-linked retinitis pigmentosa 2.

Q9BXI6	TB10A_HUMAN	TBC1 domain family member 10A	11285285	Identification of EPI64, a TBC/rabGAP domain-containing microvillar protein that binds to the first PDZ domain of EBP50 and E3KARP.

Q75J96	RGAP1_DICDI	RapA guanosine triphosphatase-activating protein 1	18039932	Regulation of Rap1 activity by RapGAP1 controls cell adhesion at the front of chemotaxing cells.

P53104	ATG1_YEAST	Serine/threonine-protein kinase ATG1	9224897	Apg1p, a novel protein kinase required for the autophagic process in Saccharomyces cerevisiae.

Q8K3L6	GIMA5_RAT	GTPase IMAP family member 5	12930893	Ian4 is required for mitochondrial integrity and T cell survival.

Q10990	CDT2_SCHPO	Cell division cycle protein cdt2	16252005	Transactivation of Schizosaccharomyces pombe cdt2+ stimulates a Pcu4- Ddb1-CSN ubiquitin ligase.

P22135	ATP12_YEAST	Protein ATP12, mitochondrial	1826907	Characterization of ATP12, a yeast nuclear gene required for the assembly of the mitochondrial F1-ATPase.

Q99MV2	TX19A_MOUSE	Testis-expressed protein 19.1	18096721	Tex19, a mammalian-specific protein with a restricted expression in pluripotent stem cells and germ line.

P45973	CBX5_HUMAN	Chromobox protein homolog 5	15882967	The mammalian heterochromatin protein 1 binds diverse nuclear proteins through a common motif that targets the chromoshadow domain.

Q9JHS3	MAPIP_MOUSE	Mitogen-activated protein-binding protein-interacting protein	15016825	The structure of the MAPK scaffold, MP1, bound to its partner, p14. A complex with a critical role in endosomal MAP kinase signaling.

Q04868	ELP6_YEAST	Elongator complex protein 6	11689709	Characterization of a six-subunit holo-elongator complex required for the regulated expression of a group of genes in Saccharomyces cerevisiae.

P62253	UB2G1_HUMAN	Ubiquitin-conjugating enzyme E2 G1	8893823	Molecular cloning of UBE2G, encoding a human skeletal muscle-specific ubiquitin-conjugating enzyme homologous to UBC7 of C. elegans.

Q42551	SCE1_ARATH	SUMO-conjugating enzyme SCE1	17644626	Genetic analysis of SUMOylation in Arabidopsis: conjugation of SUMO1 and SUMO2 to nuclear proteins is essential.

P30793	GCH1_HUMAN	GTP cyclohydrolase 1	7678411	Pteridine biosynthesis in human endothelial cells. Impact on nitric oxide-mediated formation of cyclic GMP.

P43140	ADA1A_RAT	Alpha-1A adrenergic receptor	7935320	The rat homologue of the bovine alpha 1c-adrenergic receptor shows the pharmacological properties of the classical alpha 1A subtype.

O95429	BAG4_HUMAN	BAG family molecular chaperone regulator 4	9873016	An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators.

P30556	AGTR1_HUMAN	Type-1 angiotensin II receptor	1378723	Cloning, expression, and characterization of a gene encoding the human angiotensin II type 1A receptor.

P53368	8ODP_MOUSE	7,8-dihydro-8-oxoguanine triphosphatase	7592783	Mouse MTH1 protein with 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'- triphosphatase activity that prevents transversion mutation. cDNA cloning and tissue distribution.

Q08001	YL072_YEAST	Uncharacterized protein YLR072W	14562095	Global analysis of protein localization in budding yeast.

Q06325	YPS7_YEAST	Aspartic proteinase yapsin-7	14562095	Global analysis of protein localization in budding yeast.

P34167	IF4B_YEAST	Eukaryotic translation initiation factor 4B	8404865	A Saccharomyces cerevisiae homologue of mammalian translation initiation factor 4B contributes to RNA helicase activity.

Q12418	GIS3_YEAST	Protein GIS3	14562095	Global analysis of protein localization in budding yeast.

Q12161	PSH1_YEAST	RING finger protein PSH1	12242279	RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach.

O88282	BCL6B_MOUSE	B-cell CLL/lymphoma 6 member B protein	9632807	BAZF, a novel Bcl6 homolog, functions as a transcriptional repressor.

O74928	PUR9_SCHPO	Bifunctional purine biosynthesis protein ade10	9802209	Molecular cloning and sequence analysis of the Schizosaccharomyces pombe ade10+ gene.

Q946J8	LHP1_ARATH	Chromo domain-containing protein LHP1	16244868	The Arabidopsis LHP1 protein is a component of euchromatin.

Q05513	KPCZ_HUMAN	Protein kinase C zeta type	8224878	The cDNA sequence encoding human protein kinase C-zeta.

P08047	SP1_HUMAN	Transcription factor Sp1	19666599	Human BAHD1 promotes heterochromatic gene silencing.

P19356	HEM3_RAT	Porphobilinogen deaminase	9344466	Rat harderian gland porphobilinogen deaminase: characterization studies and regulatory action of protoporphyrin IX.

P19174	PLCG1_HUMAN	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1	7681365	Solution structure of the SH3 domain of phospholipase C-gamma.

P07266	MRS1_YEAST	Mitochondrial RNA-splicing protein MRS1	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q39090	UFO_ARATH	Protein UNUSUAL FLORAL ORGANS	12169662	The F-box subunit of the SCF E3 complex is encoded by a diverse superfamily of genes in Arabidopsis.

Q94126	CES2_CAEEL	Cell death specification protein 2	8700229	Transcriptional regulator of programmed cell death encoded by Caenorhabditis elegans gene ces-2.

Q9UM54	MYO6_HUMAN	Myosin-VI	11447109	Myosin VI isoform localized to clathrin-coated vesicles with a role in clathrin-mediated endocytosis.

Q7TN16	HHIP_MOUSE	Hedgehog-interacting protein	10050855	Vertebrate Hedgehog signalling modulated by induction of a Hedgehog- binding protein.

P45985	MP2K4_HUMAN	Dual specificity mitogen-activated protein kinase kinase 4	7716521	Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2.

P46411	EAA1_BOVIN	Excitatory amino acid transporter 1	7723632	Cloning and expression of a bovine glutamate transporter.

Q8VZG8	Y4885_ARATH	Probable LRR receptor-like serine/threonine-protein kinase At4g08850	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q92630	DYRK2_HUMAN	Dual specificity tyrosine-phosphorylation-regulated kinase 2	9748265	Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases.

P58418	CLRN1_HUMAN	Clarin-1	15521980	Mutation screening of USH3 gene (clarin-1) in Spanish patients with Usher syndrome: low prevalence and phenotypic variability.

P00929	TRPA_SALTY	Tryptophan synthase alpha chain	12460570	On the role of alphaThr183 in the allosteric regulation and catalytic mechanism of tryptophan synthase.

Q08562	ULS1_YEAST	ATP-dependent helicase ULS1	18603780	SUMO mediates interaction of Ebp2p, the yeast homolog of Epstein-Barr virus nuclear antigen 1-binding protein 2, with a RING finger protein Ris1p.

Q9SS48	SDP6_ARATH	Glycerol-3-phosphate dehydrogenase SDP6, mitochondrial	18599644	SUGAR-DEPENDENT6 encodes a mitochondrial flavin adenine dinucleotide- dependent glycerol-3-p dehydrogenase, which is required for glycerol catabolism and post germinative seedling growth in Arabidopsis.

P40485	SLM1_YEAST	Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1	15372071	Genome-wide lethality screen identifies new PI4,5P2 effectors that regulate the actin cytoskeleton.

P50275	ASE1_YEAST	Anaphase spindle elongation protein	7559759	Two microtubule-associated proteins required for anaphase spindle movement in Saccharomyces cerevisiae.

Q04121	NHX1_YEAST	Endosomal/prevacuolar sodium/hydrogen exchanger	10998367	Arabidopsis thaliana and Saccharomyces cerevisiae NHX1 genes encode amiloride sensitive electroneutral Na(+)/H(+) exchangers.

O60103	DOA10_SCHPO	ERAD-associated E3 ubiquitin-protein ligase doa10	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P47089	DENR_YEAST	Translation machinery-associated protein 22	16702403	Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes.

Q7K1V5	JAGN_DROME	Protein jagunal	17389229	Jagunal is required for reorganizing the endoplasmic reticulum during Drosophila oogenesis.

Q810B8	SLIK4_MOUSE	SLIT and NTRK-like protein 4	14550773	Identification and characterization of Slitrk, a novel neuronal transmembrane protein family controlling neurite outgrowth.

Q8LGE3	ARP6_ARATH	Actin-related protein 6	11891255	Arabidopsis contains ancient classes of differentially expressed actin-related protein genes.

Q9UBC3	DNM3B_HUMAN	DNA (cytosine-5)-methyltransferase 3B	16682412	The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells.

Q8C0C0	ZHX2_MOUSE	Zinc fingers and homeoboxes protein 2	14659886	The mouse zinc-fingers and homeoboxes (ZHX) family: ZHX2 forms a heterodimer with ZHX3.

Q8LE52	DHAR3_ARATH	Glutathione S-transferase DHAR3, chloroplastic	16207701	The oligomeric stromal proteome of Arabidopsis thaliana chloroplasts.

Q8N531	FBXL6_HUMAN	F-box/LRR-repeat protein 6	10531035	Identification of a family of human F-box proteins.

P16235	LSHR_RAT	Lutropin-choriogonadotropic hormone receptor	2601325	Characterization and structure of ovarian and testicular LH/hCG receptors.

P28370	SMCA1_HUMAN	Probable global transcription activator SNF2L1	14609955	Isolation of human NURF: a regulator of Engrailed gene expression.

P55210	CASP7_HUMAN	Caspase-7	8567622	Identification and characterization of CPP32/Mch2 homolog 1, a novel cysteine protease similar to CPP32.

P23204	PPARA_MOUSE	Peroxisome proliferator-activated receptor alpha	12955147	Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-alpha.

Q19272	MSH5_CAEEL	MutS protein homolog 5	11014811	Caenorhabditis elegans msh-5 is required for both normal and radiation-induced meiotic crossing over but not for completion of meiosis.

Q63789	P55G_RAT	Phosphatidylinositol 3-kinase regulatory subunit gamma	8621382	A novel 55-kDa regulatory subunit for phosphatidylinositol 3-kinase structurally similar to p55PIK is generated by alternative splicing of the p85alpha gene.

P62241	RS8_HUMAN	40S ribosomal protein S8	8432552	The structure of the human intron-containing S8 ribosomal protein gene and determination of its chromosomal location at 1p32-p34.1.

P14316	IRF2_HUMAN	Interferon regulatory factor 2	9540062	The integrated activities of IRF-2 (HiNF-M), CDP/cut (HiNF-D) and H4TF-2 (HiNF-P) regulate transcription of a cell cycle controlled human histone H4 gene: mechanistic differences between distinct H4 genes.

P47211	GALR1_HUMAN	Galanin receptor type 1	7524088	Molecular cloning of a functional human galanin receptor.

O94585	YQ7D_SCHPO	Meiotically up-regulated protein C1442.13c	12161753	The transcriptional program of meiosis and sporulation in fission yeast.

O82132	DRE2A_ARATH	Dehydration-responsive element-binding protein 2A	18552202	Arabidopsis DREB2A-interacting proteins function as RING E3 ligases and negatively regulate plant drought stress-responsive gene expression.

P51668	UB2D1_HUMAN	Ubiquitin-conjugating enzyme E2 D1	20061386	The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.

Q61730	IL1AP_MOUSE	Interleukin-1 receptor accessory protein	10854325	Tollip, a new component of the IL-1R1 pathway, links IRAK to the IL-1 receptor.

Q9FFS0	RTNLD_ARATH	Reticulon-like protein B4	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q13227	GPS2_HUMAN	G protein pathway suppressor 2	8943324	Two human cDNAs, including a homolog of Arabidopsis FUS6 (COP11), suppress G-protein- and mitogen-activated protein kinase-mediated signal transduction in yeast and mammalian cells.

Q10173	NUF2_SCHPO	Kinetochore protein nuf2	16079914	Molecular analysis of kinetochore architecture in fission yeast.

Q96EY1	DNJA3_HUMAN	DnaJ homolog subfamily A member 3, mitochondrial	11679576	hTid-1, a human DnaJ protein, modulates the interferon signaling pathway.

P54651	HSC90_DICDI	Heat shock cognate 90 kDa protein	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

Q92879	CELF1_HUMAN	CUGBP Elav-like family member 1	8948631	Identification of a (CUG)n triplet repeat RNA-binding protein and its expression in myotonic dystrophy.

P13727	PRG2_HUMAN	Bone marrow proteoglycan	1565101	Purification and cDNA cloning of a novel factor produced by a human T-cell hybridoma: sequence homology with animal lectins.

Q6PBN2	AIDA_DANRE	Axin interactor, dorsalization-associated protein	17681137	A beta-catenin-independent dorsalization pathway activated by Axin/JNK signaling and antagonized by aida.

Q9Z1Z3	EPN2_RAT	Epsin-2	10567358	The epsins define a family of proteins that interact with components of the clathrin coat and contain a new protein module.

Q9Y7S6	AATR3_SCHPO	Aromatic amino acid aminotransferase C569.07	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P34556	CDK1_CAEEL	Cell division protein kinase 1	10207147	The Caenorhabditis elegans gene ncc-1 encodes a cdc2-related kinase required for M phase in meiotic and mitotic cell divisions, but not for S phase.

Q38849	KAT2_ARATH	Potassium channel KAT2	11042178	Guard cell inward K+ channel activity in Arabidopsis involves expression of the twin channel subunits KAT1 and KAT2.

O75503	CLN5_HUMAN	Ceroid-lipofuscinosis neuronal protein 5	9662406	CLN5, a novel gene encoding a putative transmembrane protein mutated in Finnish variant late infantile neuronal ceroid lipofuscinosis.

Q864V4	UPK3B_BOVIN	Uroplakin-3b	12446744	Uroplakin IIIb, a urothelial differentiation marker, dimerizes with uroplakin Ib as an early step of urothelial plaque assembly.

O43603	GALR2_HUMAN	Galanin receptor type 2	9480833	Cloning and expression of the human galanin receptor GalR2.

Q9Y2G2	CARD8_HUMAN	Caspase recruitment domain-containing protein 8	11551959	CARDINAL, a novel caspase recruitment domain protein, is an inhibitor of multiple NF-kappa B activation pathways.

P46467	VPS4B_MOUSE	Vacuolar protein sorting-associated protein 4B	8082782	Identification of a novel mammalian member of the NSF/CDC48p/Pas1p/TBP-1 family through heterologous expression in yeast.

Q9BTZ2	DHRS4_HUMAN	Dehydrogenase/reductase SDR family member 4	10333503	Identification of peroxisomal proteins by using M13 phage protein VI phage display: molecular evidence that mammalian peroxisomes contain a 2,4-dienoyl-CoA reductase.

P08683	CP2CB_RAT	Cytochrome P450 2C11	8611037	cDNA-directed expression of two allelic variants of cytochrome P450 2C11 using COS1 and SF21 insect cells.

P70255	NFIC_MOUSE	Nuclear factor 1 C-type	9056636	Expression patterns of the four nuclear factor I genes during mouse embryogenesis indicate a potential role in development.

Q93VR3	GME_ARATH	GDP-mannose 3,5-epimerase	12954627	GDP-mannose 3',5'-epimerase forms GDP-L-gulose, a putative intermediate for the de novo biosynthesis of vitamin C in plants.

O24410	IAA20_ARATH	Auxin-responsive protein IAA20	12036262	Genetics of Aux/IAA and ARF action in plant growth and development.

O75563	SKAP2_HUMAN	Src kinase-associated phosphoprotein 2	9837776	RA70 is a src kinase-associated protein expressed ubiquitously.

O75787	RENR_HUMAN	Renin receptor	12045255	Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin.

Q9Z273	TULP1_MOUSE	Tubby-related protein 1	19218615	Early synaptic defects in tulp1-/- mice.

O74198	ERG6_CANAL	Sterol 24-C-methyltransferase	9593144	Sequencing, disruption, and characterization of the Candida albicans sterol methyltransferase (ERG6) gene: drug susceptibility studies in erg6 mutants.

P11233	RALA_HUMAN	Ras-related protein Ral-A	7673236	Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity.

Q99KE3	DOK4_MOUSE	Docking protein 4	11470823	Novel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation.

P0ACB4	HEMG_ECOLI	Protoporphyrinogen IX dehydrogenase [menaquinone]	7788523	Cloning and identification of the hemG gene encoding protoporphyrinogen oxidase (PPO) of Escherichia coli K-12.

P32768	FLO1_YEAST	Flocculation protein FLO1	9483793	Distribution of the flocculation protein, flop, at the cell surface during yeast growth: the availability of flop determines the flocculation level.

P53840	TOF1_YEAST	Topoisomerase 1-associated factor 1	14742714	Identification of protein complexes required for efficient sister chromatid cohesion.

P0ABZ4	KDSC_ECOLI	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase	12639950	Escherichia coli YrbI is 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase.

Q9P779	YNYB_SCHPO	Sorting nexin C1711.11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9US56	MUG31_SCHPO	Meiotically up-regulated gene 31 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8WTS6	SETD7_HUMAN	Histone-lysine N-methyltransferase SETD7	16415881	Structural basis for the methylation site specificity of SET7/9.

P52788	SPSY_HUMAN	Spermine synthase	7546290	Molecular cloning of a cDNA encoding human spermine synthase.

Q9FIJ0	RBOHD_ARATH	Respiratory burst oxidase homolog protein D	11756663	Arabidopsis gp91phox homologues AtrbohD and AtrbohF are required for accumulation of reactive oxygen intermediates in the plant defense response.

O88453	SAFB1_RAT	Scaffold attachment factor B1	9671816	SAF-B couples transcription and pre-mRNA splicing to SAR/MAR elements.

Q8L9W3	ATL23_ARATH	E3 ubiquitin-protein ligase ATL23	16339806	Genome analysis and functional characterization of the E2 and RING- type E3 ligase ubiquitination enzymes of Arabidopsis.

Q9DG36	GON2_RANCA	Progonadoliberin-2	11170016	Cloning and characterization of cDNAs encoding the GnRH1 and GnRH2 precursors from bullfrog (Rana catesbeiana).

Q9ESQ9	RFRP_RAT	FMRFamide-related peptides	11481330	Identification and characterization of novel mammalian neuropeptide FF-like peptides that attenuate morphine-induced antinociception.

Q9S9U0	CALSB_ARATH	Callose synthase 11	16021399	Two callose synthases, GSL1 and GSL5, play an essential and redundant role in plant and pollen development and in fertility.

P15516	HIS3_HUMAN	Histatin-3	8336540	Nucleotide sequence analysis of the human salivary protein genes HIS1 and HIS2, and evolution of the STATH/HIS gene family.

P50498	MSA2_PLAF7	Merozoite surface antigen 2	2181307	Structural diversity in the 45-kilodalton merozoite surface antigen of Plasmodium falciparum.

P32874	HFA1_YEAST	Acetyl-CoA carboxylase, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

Q8S8Y9	WNK2_ARATH	Serine/threonine-protein kinase WNK2	12506983	Compilation and characterization of a novel WNK family of protein kinases in Arabiodpsis thaliana with reference to circadian rhythms.

Q9Y7K5	YGI3_SCHPO	Uncharacterized WD repeat-containing protein C2A9.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P38781	RSC30_YEAST	Chromatin structure-remodeling complex protein RSC30	11336698	A Rsc3/Rsc30 zinc cluster dimer reveals novel roles for the chromatin remodeler RSC in gene expression and cell cycle control.

P40308	TGL3_YEAST	Lipase 3	12682047	YMR313c/TGL3 encodes a novel triacylglycerol lipase located in lipid particles of Saccharomyces cerevisiae.

O14582	TPPC2_HUMAN	Trafficking protein particle complex subunit 2	10431248	Identification of the gene (SEDL) causing X-linked spondyloepiphyseal dysplasia tarda.

P87227	MIS6_SCHPO	Inner centromere protein mis6	9230309	Mis6, a fission yeast inner centromere protein, acts during G1/S and forms specialized chromatin required for equal segregation.

Q9HCT0	FGF22_HUMAN	Fibroblast growth factor 22	11342227	Identification of a novel fibroblast growth factor, FGF-22, preferentially expressed in the inner root sheath of the hair follicle.

B7ZSG3	WT1A_XENLA	Wilms tumor protein homolog A	19549856	An integrated genome screen identifies the Wnt signaling pathway as a major target of WT1.

P33077	IAA4_ARATH	Auxin-responsive protein IAA4	8278386	Early auxin-induced genes encode short-lived nuclear proteins.

Q99N43	KREM1_MOUSE	Kremen protein 1	11267660	Molecular cloning and characterization of Kremen, a novel kringle- containing transmembrane protein.

P51817	PRKX_HUMAN	Serine/threonine-protein kinase PRKX	7633447	The human protein kinase gene PKX1 on Xp22.3 displays Xp/Yp homology and is a site of chromosomal instability.

Q05754	DOPO_RAT	Dopamine beta-hydroxylase	2325165	Rat dopamine beta-hydroxylase: molecular cloning and characterization of the cDNA and regulation of the mRNA by reserpine.

Q27571	NOS_DROME	Nitric oxide synthase	11526108	The Drosophila nitric-oxide synthase gene (dNOS) encodes a family of proteins that can modulate NOS activity by acting as dominant negative regulators.

Q12959	DLG1_HUMAN	Disks large homolog 1	14699157	Human homolog of disc-large is required for adherens junction assembly and differentiation of human intestinal epithelial cells.

P25063	CD24_HUMAN	Signal transducer CD24	11313396	CD24 induces apoptosis in human B cells via the glycolipid-enriched membrane domains/rafts-mediated signaling system.

Q00IB7	PKHH1_DANRE	Pleckstrin homology domain-containing family H member 1	17065323	Vertebrate MAX-1 is required for vascular patterning in zebrafish.

O15228	GNPAT_HUMAN	Dihydroxyacetone phosphate acyltransferase	9536089	Acyl-CoA:dihydroxyacetonephosphate acyltransferase: cloning of the human cDNA and resolution of the molecular basis in rhizomelic chondrodysplasia punctata type 2.

O60783	RT14_HUMAN	28S ribosomal protein S14, mitochondrial	10938081	A proteomics approach to the identification of mammalian mitochondrial small subunit ribosomal proteins.

Q04149	MUS81_YEAST	Crossover junction endonuclease MUS81	11139495	Requirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiae.

Q14406	CSHL_HUMAN	Chorionic somatomammotropin hormone-like 1	2744760	The human growth hormone locus: nucleotide sequence, biology, and evolution.

Q08444	NOB1_YEAST	20S-pre-rRNA D-site endonuclease NOB1	15388878	PIN domain of Nob1p is required for D-site cleavage in 20S pre- rRNA.

Q08193	GAS5_YEAST	1,3-beta-glucanosyltransferase GAS5	15781460	Comprehensive proteomic analysis of Saccharomyces cerevisiae cell walls: identification of proteins covalently attached via glycosylphosphatidylinositol remnants or mild alkali-sensitive linkages.

P25157	GNAL_DROME	Guanine nucleotide-binding protein subunit alpha homolog	1899050	The Drosophila gastrulation gene concertina encodes a G alpha-like protein.

Q14574	DSC3_HUMAN	Desmocollin-3	7929347	cDNA cloning and expression of a novel human desmocollin.

Q9SWI1	PKS1_ARATH	Protein PHYTOCHROME KINASE SUBSTRATE 1	14615593	A growth regulatory loop that provides homeostasis to phytochrome a signaling.

O70305	ATX2_MOUSE	Ataxin-2	9668173	The mouse SCA2 gene: cDNA sequence, alternative splicing and protein expression.

Q09176	U2AF1_SCHPO	Splicing factor U2AF 23 kDa subunit	12374752	Pre-spliceosome formation in S.pombe requires a stable complex of SF1-U2AF(59)-U2AF(23).

O94374	IMA2_SCHPO	Importin subunit alpha-2	15116432	Identification of genes encoding putative nucleoporins and transport factors in the fission yeast Schizosaccharomyces pombe: a deletion analysis.

P68644	FIXC_ECOLI	Protein fixC	7473063	The fix Escherichia coli region contains four genes related to carnitine metabolism.

P93830	IAA17_ARATH	Auxin-responsive protein IAA17	9478901	Changes in auxin response from mutations in an AUX/IAA gene.

Q8K136	SCNM1_MOUSE	Sodium channel modifier 1	12920299	SCNM1, a putative RNA splicing factor that modifies disease severity in mice.

Q15654	TRIP6_HUMAN	Thyroid receptor-interacting protein 6	16137684	The tumor suppressor Scrib selectively interacts with specific members of the zyxin family of proteins.

Q91619	NODAL_XENLA	Nodal homolog	9310324	Functional differences among Xenopus nodal-related genes in left- right axis determination.

O74380	YNV5_SCHPO	Uncharacterized membrane protein C3H7.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8MPQ7	OSB1_DICDI	Oxysterol-binding protein 1	12220630	OSBPa, a predicted oxysterol binding protein of Dictyostelium, is required for regulated entry into culmination.

P24088	YRF11_YEAST	Y' element ATP-dependent helicase protein 1 copies 1/5/8	9837911	Y'-Help1, a DNA helicase encoded by the yeast subtelomeric Y' element, is induced in survivors defective for telomerase.

P42835	EGT2_YEAST	Protein EGT2	15452134	GPI7 involved in glycosylphosphatidylinositol biosynthesis is essential for yeast cell separation.

Q9ULV1	FZD4_HUMAN	Frizzled-4	12172548	Mutant frizzled-4 disrupts retinal angiogenesis in familial exudative vitreoretinopathy.

P0AFD1	NUOE_ECOLI	NADH-quinone oxidoreductase subunit E	7607227	Isolation and characterization of the proton-translocating NADH: ubiquinone oxidoreductase from Escherichia coli.

Q7TSF1	DSG1B_MOUSE	Desmoglein-1-beta	12631242	Novel member of the mouse desmoglein gene family: Dsg1-beta.

Q9ZNT9	FIS2_ARATH	Polycomb group protein FERTILIZATION-INDEPENDENT SEED 2	10962025	Expression and parent-of-origin effects for FIS2, MEA, and FIE in the endosperm and embryo of developing Arabidopsis seeds.

Q6TLK4	RHG27_RAT	Rho GTPase-activating protein 27	15147912	Identification and characterization of a novel Rho GTPase activating protein implicated in receptor-mediated endocytosis.

A0ZWU1	EAF1_SCHPO	Ell1-associated factor 1	17150956	Identification and characterization of a Schizosaccharomyces pombe RNA polymerase II elongation factor with similarity to the metazoan transcription factor ELL.

Q966R0	CBPI_DICDI	Calcium-binding protein I	14706075	Identification and characterization of novel calcium-binding proteins of Dictyostelium and their spatial expression patterns during development.

Q54DG1	ALDH3_DICDI	Aldehyde dehydrogenase family 3 comG	12871696	A novel developmental mechanism in Dictyostelium revealed in a screen for communication mutants.

P69506	RCMNS_ECOLI	Regulator of cell morphogenesis and NO signaling	15546870	New genes implicated in the protection of anaerobically grown Escherichia coli against nitric oxide.

Q09173	PP2C3_SCHPO	Protein phosphatase 2C homolog 3	7859738	Counteractive roles of protein phosphatase 2C (PP2C) and a MAP kinase kinase homolog in the osmoregulation of fission yeast.

Q9JKY0	RCD1_MOUSE	Cell differentiation protein RCD1 homolog	10880228	Subtraction cloning and initial characterization of novel EPO- immediate response genes.

Q12933	TRAF2_HUMAN	TNF receptor-associated factor 2	9692890	The TNF receptor family member CD27 signals to Jun N-terminal kinase via Traf-2.

Q76LD0	CRDL1_RAT	Chordin-like protein 1	14684875	A novel secretory factor, neurogenesin-1, provides neurogenic environmental cues for neural stem cells in the adult hippocampus.

P15884	ITF2_HUMAN	Transcription factor 4	1681116	Helix-loop-helix transcriptional activators bind to a sequence in glucocorticoid response elements of retrovirus enhancers.

P52923	AIF1_YEAST	Apoptosis-inducing factor 1	11409174	A novel putative reductase (Cpd1p) and the multidrug exporter Snq2p are involved in resistance to cercosporin and other singlet oxygen- generating photosensitizers in Saccharomyces cerevisiae.

O75575	RPC9_HUMAN	DNA-directed RNA polymerase III subunit RPC9	12482973	An Rpb4/Rpb7-like complex in yeast RNA polymerase III contains the orthologue of mammalian CGRP-RCP.

P21860	ERBB3_HUMAN	Receptor tyrosine-protein kinase erbB-3	2687875	Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumors.

Q99M04	LIAS_MOUSE	Lipoyl synthase, mitochondrial	11389890	Do mammalian cells synthesize lipoic acid? Identification of a mouse cDNA encoding a lipoic acid synthase located in mitochondria.

Q9UQB8	BAIP2_HUMAN	Brain-specific angiogenesis inhibitor 1-associated protein 2	10343108	Identification of BAIAP2 (BAI-associated protein 2), a novel human homologue of hamster IRSp53, whose SH3 domain interacts with the cytoplasmic domain of BAI1.

O94487	PPK35_SCHPO	Serine/threonine-protein kinase ppk35	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

P13693	TCTP_HUMAN	Translationally-controlled tumor protein	15958728	The translationally controlled tumor protein is a novel calcium binding protein of the human placenta and regulates calcium handling in trophoblast cells.

O75319	DUS11_HUMAN	RNA/RNP complex-1-interacting phosphatase	9685386	PIR1, a novel phosphatase that exhibits high affinity to RNA ribonucleoprotein complexes.

P39210	MPV17_HUMAN	Protein Mpv17	16582910	MPV17 encodes an inner mitochondrial membrane protein and is mutated in infantile hepatic mitochondrial DNA depletion.

Q60714	S27A1_MOUSE	Long-chain fatty acid transport protein 1	14991074	Inactivation of fatty acid transport protein 1 prevents fat-induced insulin resistance in skeletal muscle.

Q7Z995	YGMI_SCHPO	Uncharacterized protein C19G7.18c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q43307	PLSB_ARATH	Glycerol-3-phosphate acyltransferase, chloroplastic	7678766	The gene and the RNA for the precursor to the plastid-located glycerol-3-phosphate acyltransferase of Arabidopsis thaliana.

Q9N0E7	MOCOS_BOVIN	Molybdenum cofactor sulfurase	10801779	Deletion mutation in Droshophila ma-l homologous, putative molybdopterin cofactor sulfurase gene is associated with bovine xanthinuria type II.

P97846	CNTP1_RAT	Contactin-associated protein 1	9292722	Paranodin, a glycoprotein of neuronal paranodal membranes.

Q9US43	UPP3_SCHPO	Putative uracil phosphoribosyltransferase urg2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q13790	APOF_HUMAN	Apolipoprotein F	8093033	Purification and molecular cloning of human apolipoprotein F.

P41888	TNR3_SCHPO	Thiamine pyrophosphokinase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P35584	FOXA3_MOUSE	Hepatocyte nuclear factor 3-gamma	17488644	Impaired male fertility and atrophy of seminiferous tubules caused by haploinsufficiency for Foxa3.

Q9VZZ4	PXDN_DROME	Peroxidasin	8062820	Peroxidasin: a novel enzyme-matrix protein of Drosophila development.

Q6PFW1	VIP1_HUMAN	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1	17412958	A conserved family of enzymes that phosphorylate inositol hexakisphosphate.

Q9H2X0	CHRD_HUMAN	Chordin	9782094	Coding sequence and expression patterns of mouse chordin and mapping of the cognate mouse chrd and human CHRD genes.

P80644	SSUE_ECOLI	FMN reductase	8774726	Analysis of global responses by protein and peptide fingerprinting of proteins isolated by two-dimensional gel electrophoresis. Application to the sulfate-starvation response of Escherichia coli.

P53966	KTR5_YEAST	Probable mannosyltransferase KTR5	9090056	Completion of the Saccharomyces cerevisiae genome sequence allows identification of KTR5, KTR6 and KTR7 and definition of the nine- membered KRE2/MNT1 mannosyltransferase gene family in this organism.

Q9TXJ0	CMK1_CAEEL	Calcium/calmodulin-dependent protein kinase type 1	10428833	Ca(2+)/Calmodulin-dependent protein kinase cascade in Caenorhabditis elegans. Implication in transcriptional activation.

Q9FRR1	PRA1E_ARATH	PRA1 family protein E	18583532	The PRA1 gene family in Arabidopsis.

P70562	BHA15_RAT	Class A basic helix-loop-helix protein 15	9073453	Mist1: a novel basic helix-loop-helix transcription factor exhibits a developmentally regulated expression pattern.

O98679	NDHK_PEA	NAD(P)H-quinone oxidoreductase subunit K, chloroplastic	9448329	The plastid ndh genes code for an NADH-specific dehydrogenase: isolation of a complex I analogue from pea thylakoid membranes.

P75989	YCGE_ECOLI	HTH-type transcriptional repressor YcgE	19240136	The BLUF-EAL protein YcgF acts as a direct anti-repressor in a blue- light response of Escherichia coli.

Q91VF2	HNMT_MOUSE	Histamine N-methyltransferase	11475331	Mouse histamine N-methyltransferase: cDNA cloning, expression, gene cloning and chromosomal localization.

Q9UM13	APC10_HUMAN	Anaphase-promoting complex subunit 10	16364912	Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C.

Q9S746	HTH_ARATH	Protein HOTHEAD	12904212	Isolation and characterization of the Arabidopsis organ fusion gene HOTHEAD.

P28347	TEAD1_HUMAN	Transcriptional enhancer factor TEF-1	19324877	TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition.

O76054	S14L2_HUMAN	SEC14-like protein 2	11226224	Supernatant protein factor, which stimulates the conversion of squalene to lanosterol, is a cytosolic squalene transfer protein and enhances cholesterol biosynthesis.

P25870	CLH_DICDI	Clathrin heavy chain	11223952	Cytokinesis failure in clathrin-minus cells is caused by cleavage furrow instability.

Q86VZ5	SMS1_HUMAN	Phosphatidylcholine:ceramide cholinephosphotransferase 1	14976195	Expression cloning of a human cDNA restoring sphingomyelin synthesis and cell growth in sphingomyelin synthase-defective lymphoid cells.

Q9ZQG9	E1314_ARATH	Glucan endo-1,3-beta-glucosidase 14	14517339	Proteomic analysis of glycosylphosphatidylinositol-anchored membrane proteins.

Q9HCJ2	LRC4C_HUMAN	Leucine-rich repeat-containing protein 4C	14595443	The netrin-G1 ligand NGL-1 promotes the outgrowth of thalamocortical axons.

O95750	FGF19_HUMAN	Fibroblast growth factor 19	10525310	FGF-19, a novel fibroblast growth factor with unique specificity for FGFR4.

Q15025	TNIP1_HUMAN	TNFAIP3-interacting protein 1	9923610	Identification and cloning of a novel cellular protein Naf1, Nef- associated factor 1, that increases cell surface CD4 expression.

P23204	PPARA_MOUSE	Peroxisome proliferator-activated receptor alpha	18719582	PRDM16 controls a brown fat/skeletal muscle switch.

Q03919	RUB1_YEAST	NEDD8-like protein RUB1	9545234	A novel protein modification pathway related to the ubiquitin system.

O43676	NDUB3_HUMAN	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3	9878551	cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed.

Q5VZF2	MBNL2_HUMAN	Muscleblind-like protein 2	15257297	Muscleblind proteins regulate alternative splicing.

Q15049	MLC1_HUMAN	Membrane protein MLC1	11254442	Mutations of MLC1 (KIAA0027), encoding a putative membrane protein, cause megalencephalic leukoencephalopathy with subcortical cysts.

Q39239	TRXH4_ARATH	Thioredoxin H4	7777559	Evidence for five divergent thioredoxin h sequences in Arabidopsis thaliana.

Q02685	RMI1_YEAST	RecQ-mediated genome instability protein 1	15889139	RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex.

Q9V461	MCM6_DROME	DNA replication licensing factor Mcm6	11854416	Drosophila minichromosome maintenance 6 is required for chorion gene amplification and genomic replication.

Q8BGD7	NPAS4_MOUSE	Neuronal PAS domain-containing protein 4	15363889	LE-PAS, a novel Arnt-dependent HLH-PAS protein, is expressed in limbic tissues and transactivates the CNS midline enhancer element.

Q05021	TAF7_YEAST	Transcription initiation factor TFIID subunit 7	12138208	Molecular characterization of Saccharomyces cerevisiae TFIID.

Q8IWJ2	GCC2_HUMAN	GRIP and coiled-coil domain-containing protein 2	18243103	Rab and Arl GTPase family members cooperate in the localization of the golgin GCC185.

O14654	IRS4_HUMAN	Insulin receptor substrate 4	9261155	A novel 160-kDa phosphotyrosine protein in insulin-treated embryonic kidney cells is a new member of the insulin receptor substrate family.

P09871	C1S_HUMAN	Complement C1s subcomponent	11527969	Substrate specificities of recombinant mannan-binding lectin- associated serine proteases-1 and -2.

Q8LEM7	CNBL3_ARATH	Calcineurin B-like protein 3	17898163	A protein phosphorylation/dephosphorylation network regulates a plant potassium channel.

O09101	PIGF_MOUSE	Phosphatidylinositol-glycan biosynthesis class F protein	10781593	Requirement of PIG-F and PIG-O for transferring phosphoethanolamine to the third mannose in glycosylphosphatidylinositol.

P85058	RNS2B_RANSV	Ranatuerin-2SEb	16386333	Histamine-releasing and antimicrobial peptides from the skin secretions of the dusky gopher frog, Rana sevosa.

Q9UT24	BRR2_SCHPO	Pre-mRNA-splicing factor brr2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9GZM8	NDEL1_HUMAN	Nuclear distribution protein nudE-like 1	12812986	DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation.

Q03112	EVI1_HUMAN	MDS1 and EVI1 complex locus protein EVI1	11568182	Interaction of EVI1 with cAMP-responsive element-binding protein- binding protein (CBP) and p300/CBP-associated factor (P/CAF) results in reversible acetylation of EVI1 and in co-localization in nuclear speckles.

Q8TDB6	DTX3L_HUMAN	E3 ubiquitin-protein ligase DTX3L	16809771	BAL1 and BBAP are regulated by a gamma interferon-responsive bidirectional promoter and are overexpressed in diffuse large B-cell lymphomas with a prominent inflammatory infiltrate.

P22523	MUKB_ECOLI	Chromosome partition protein mukB	1989883	The new gene mukB codes for a 177 kd protein with coiled-coil domains involved in chromosome partitioning of E. coli.

Q9NAN2	PAR6_CAEEL	Partitioning defective protein 6	9834192	PAR-6 is a conserved PDZ domain-containing protein that colocalizes with PAR-3 in Caenorhabditis elegans embryos.

P38873	KOG1_YEAST	Target of rapamycin complex 1 subunit KOG1	16394584	LAS24/KOG1, a component of the TOR complex 1 (TORC1), is needed for resistance to local anesthetic tetracaine and normal distribution of actin cytoskeleton in yeast.

Q20930	MIG17_CAEEL	ADAM family mig-17	14688791	An NDPase links ADAM protease glycosylation with organ morphogenesis in C. elegans.

O46339	HTH_DROME	Homeobox protein homothorax	9450936	The Homothorax homeoprotein activates the nuclear localization of another homeoprotein, extradenticle, and suppresses eye development in Drosophila.

P47900	P2RY1_HUMAN	P2Y purinoceptor 1	8630005	Cloning and tissue distribution of the human P2Y1 receptor.

Q99814	EPAS1_HUMAN	Endothelial PAS domain-containing protein 1	9079689	Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway.

Q29408	IL10_SHEEP	Interleukin-10	7622047	Cloning and characterisation of an ovine interleukin-10-encoding cDNA.

Q9YGK8	IRX1A_XENLA	Iroquois-class homeodomain protein irx-1-A	11923198	The homeoprotein Xiro1 is required for midbrain-hindbrain boundary formation.

Q56WD9	THIK2_ARATH	3-ketoacyl-CoA thiolase 2, peroxisomal	9490742	2,4-Dichlorophenoxybutyric acid-resistant mutants of Arabidopsis have defects in glyoxysomal fatty acid beta-oxidation.

Q12519	YJ87_SCHPO	Ucharacterized MFS-type transporter C330.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

C0LGK4	Y2165_ARATH	Probable LRR receptor-like serine/threonine-protein kinase At2g16250	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q96B97	SH3K1_HUMAN	SH3 domain-containing kinase-binding protein 1	11894095	Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors.

Q8R500	MFN2_RAT	Mitofusin-2	12598526	Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity.

Q9ZT50	RHA2A_ARATH	E3 ubiquitin-protein ligase RHA2A	19286935	The Arabidopsis RING finger E3 ligase RHA2a is a novel positive regulator of abscisic acid signaling during seed germination and early seedling development.

P43003	EAA1_HUMAN	Excitatory amino acid transporter 1	8647279	Human high affinity, Na(+)-dependent L-glutamate/L-aspartate transporter GLAST-1 (EAAT-1): gene structure and localization to chromosome 5p11-p12.

O74771	YO3A_SCHPO	Uncharacterized protein C24C6.10c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8K3E7	DPY30_RAT	Protein dpy-30 homolog	19651892	A role of histone H3 lysine 4 methyltransferase components in endosomal trafficking.

P25859	CKB11_ARATH	Cyclin-dependent kinase B1-1	15031414	B1-type cyclin-dependent kinases are essential for the formation of stomatal complexes in Arabidopsis thaliana.

Q3V3I2	GNAT3_MOUSE	Guanine nucleotide-binding protein G(t) subunit alpha-3	15342734	Umami taste responses are mediated by alpha-transducin and alpha- gustducin.

Q14457	BECN1_HUMAN	Beclin-1	9765397	Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein.

P35576	G6PC_MOUSE	Glucose-6-phosphatase	8640227	Glucose-6-phosphatase dependent substrate transport in the glycogen storage disease type-1a mouse.

P21272	CEBPB_RAT	CCAAT/enhancer-binding protein beta	2171780	IL-6DBP, a nuclear protein involved in interleukin-6 signal transduction, defines a new family of leucine zipper proteins related to C/EBP.

Q65XK0	ILV5_ORYSJ	Ketol-acid reductoisomerase, chloroplastic	19362563	Conformational changes in a plant ketol-acid reductoisomerase upon Mg(2+) and NADPH binding as revealed by two crystal structures.

Q3TKT4	SMCA4_MOUSE	Transcription activator BRG1	17640523	An essential switch in subunit composition of a chromatin remodeling complex during neural development.

A2BH40	ARI1A_MOUSE	AT-rich interactive domain-containing protein 1A	17640523	An essential switch in subunit composition of a chromatin remodeling complex during neural development.

P84022	SMAD3_HUMAN	Mothers against decapentaplegic homolog 3	8774881	Receptor-associated Mad homologues synergize as effectors of the TGF- beta response.

Q9H0V9	LMA2L_HUMAN	VIP36-like protein	12878160	VIPL, a VIP36-like membrane protein with a putative function in the export of glycoproteins from the endoplasmic reticulum.

P27352	IF_HUMAN	Gastric intrinsic factor	15738392	Hereditary juvenile cobalamin deficiency caused by mutations in the intrinsic factor gene.

Q9NYB9	ABI2_HUMAN	Abl interactor 2	7590236	Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity.

P10627	TWIST_DROME	Protein twist	3416836	Sequence of the twist gene and nuclear localization of its protein in endomesodermal cells of early Drosophila embryos.

Q92358	BQT1_SCHPO	Telomere bouquet protein 1	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

O59858	GPX1_SCHPO	Glutathione peroxidase	10455235	Schizosaccharomyces pombe homologue of glutathione peroxidase, which does not contain selenocysteine, is induced by several stresses and works as an antioxidant.

P09497	CLCB_HUMAN	Clathrin light chain B	11889126	HIP1 and HIP12 display differential binding to F-actin, AP2, and clathrin. Identification of a novel interaction with clathrin light chain.

P50464	UNC97_CAEEL	LIM domain-containing protein unc-97	12808046	Caenorhabditis elegans UNC-98, a C2H2 Zn finger protein, is a novel partner of UNC-97/PINCH in muscle adhesion complexes.

P08905	LYZ2_MOUSE	Lysozyme C-2	14977423	Comparison of the microbicidal and muramidase activities of mouse lysozyme M and P.

Q6V595	KLHL6_MOUSE	Kelch-like protein 6	16166635	The BTB-kelch protein KLHL6 is involved in B-lymphocyte antigen receptor signaling and germinal center formation.

O60760	HPGDS_HUMAN	Hematopoietic prostaglandin D synthase	9353279	Prostaglandin D synthase in human megakaryoblastic cells.

Q09028	RBBP4_HUMAN	Histone-binding protein RBBP4	14609955	Isolation of human NURF: a regulator of Engrailed gene expression.

P07713	DECA_DROME	Protein decapentaplegic	10495279	Dpp and Notch specify the fusion cell fate in the dorsal branches of the Drosophila trachea.

Q8WXF1	PSPC1_HUMAN	Paraspeckle component 1	16148043	P54nrb forms a heterodimer with PSP1 that localizes to paraspeckles in an RNA-dependent manner.

P05093	CP17A_HUMAN	Steroid 17-alpha-hydroxylase/17,20 lyase	10406467	Molecular modeling of human P450c17 (17alpha-hydroxylase/17,20- lyase): insights into reaction mechanisms and effects of mutations.

P16260	GDC_HUMAN	Graves disease carrier protein	2575220	Sequence and chromosomal assignment of a novel cDNA identified by immunoscreening of a thyroid expression library: similarity to a family of mitochondrial solute carrier proteins.

Q9SA52	Y1934_ARATH	Uncharacterized protein At1g09340, chloroplastic	16461379	Protein profiling of plastoglobules in chloroplasts and chromoplasts. A surprising site for differential accumulation of metabolic enzymes.

O60664	PLIN3_HUMAN	Perilipin-3	9590177	TIP47: a cargo selection device for mannose 6-phosphate receptor trafficking.

P04431	KV123_HUMAN	Ig kappa chain V-I region Walker	6091049	Immunoglobulin genes of the kappa light chain type from two human lymphoid cell lines are closely related.

Q13315	ATM_HUMAN	Serine-protein kinase ATM	18449195	Single-stranded DNA-binding protein hSSB1 is critical for genomic stability.

Q9UM54	MYO6_HUMAN	Myosin-VI	15247260	Myosin VI regulates endocytosis of the cystic fibrosis transmembrane conductance regulator.

Q9HE08	MTNB_SCHPO	Methylthioribulose-1-phosphate dehydratase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q19469	SAD1_CAEEL	Serine/threonine kinase SAD-1	11182085	The SAD-1 kinase regulates presynaptic vesicle clustering and axon termination.

Q8TCB0	IFI44_HUMAN	Interferon-induced protein 44	7925411	Induction of the human gene for p44, a hepatitis-C-associated microtubular aggregate protein, by interferon-alpha/beta.

P40381	SWI6_SCHPO	Chromatin-associated protein swi6	8200530	Switching gene swi6, involved in repression of silent mating-type loci in fission yeast, encodes a homologue of chromatin-associated proteins from Drosophila and mammals.

Q38945	DPNPH_ARATH	PAP-specific phosphatase HAL2-like	10205895	The Arabidopsis HAL2-like gene family includes a novel sodium- sensitive phosphatase.

P38208	POP8_YEAST	Ribonucleases P/MRP protein subunit POP8	9620854	Purification and characterization of the nuclear RNase P holoenzyme complex reveals extensive subunit overlap with RNase MRP.

P15088	CBPA3_HUMAN	Mast cell carboxypeptidase A	2708524	Human mast cell carboxypeptidase. Purification and characterization.

Q12513	TMA17_YEAST	Translation machinery-associated protein 17	14562095	Global analysis of protein localization in budding yeast.

P51965	UB2E1_HUMAN	Ubiquitin-conjugating enzyme E2 E1	8576257	Cloning of human ubiquitin-conjugating enzymes UbcH6 and UbcH7 (E2- F1) and characterization of their interaction with E6-AP and RSP5.

P09093	CEL3A_HUMAN	Chymotrypsin-like elastase family member 3A	2460440	Molecular cloning of complementary DNA encoding one of the human pancreatic protease E isozymes.

Q9H074	PAIP1_HUMAN	Polyadenylate-binding protein-interacting protein 1	11997512	Paip1 interacts with poly(A) binding protein through two independent binding motifs.

P23942	PRPH2_HUMAN	Peripherin-2	1749427	A three-base-pair deletion in the peripherin-RDS gene in one form of retinitis pigmentosa.

P50111	ZDS1_YEAST	Protein ZDS1	15619606	Physical and genetic interactions link the yeast protein Zds1p with mRNA nuclear export.

P53685	HST1_YEAST	NAD-dependent deacetylase HST1	12612074	Rfm1, a novel tethering factor required to recruit the hst1 histone deacetylase for repression of middle sporulation genes.

Q1MTR7	YBPE_SCHPO	Uncharacterized oxidoreductase C16H5.14c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UT62	YKJ4_SCHPO	Uncharacterized protein C513.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q05513	KPCZ_HUMAN	Protein kinase C zeta type	9768361	Regulation of protein kinase C zeta by PI 3-kinase and PDK-1.

P39000	SHC1_YEAST	Protein SHC1	11918806	Control of chitin synthesis through Shc1p, a functional homologue of Chs4p specifically induced during sporulation.

Q9W358	RIC8_DROME	Synembryn	16228011	Drosophila Ric-8 is essential for plasma-membrane localization of heterotrimeric G proteins.

Q08696	MST2_DROHY	Axoneme-associated protein mst101(2)	7957199	Tandemly arranged repeats of a novel highly charged 16-amino-acid motif representing the major component of the sperm-tail-specific axoneme-associated protein family Dhmst101 form extended alpha-helical rods within the extremely elongated spermatozoa of Drosophila hydei.

P39734	HPH2_YEAST	Protein HPH2	15189990	Hph1p and Hph2p, novel components of calcineurin-mediated stress responses in Saccharomyces cerevisiae.

B0M0P8	GEFL_DICDI	Ras guanine nucleotide exchange factor L	16086850	The Dictyostelium genome encodes numerous RasGEFs with multiple biological roles.

O43847	NRDC_HUMAN	Nardilysin	9479496	Human NRD convertase: a highly conserved metalloendopeptidase expressed at specific sites during development and in adult tissues.

Q12873	CHD3_HUMAN	Chromodomain-helicase-DNA-binding protein 3	9326634	Characterization of the CHD family of proteins.

Q9Z0Y2	PA21B_MOUSE	Phospholipase A2	10066760	Both group IB and group IIA secreted phospholipases A2 are natural ligands of the mouse 180-kDa M-type receptor.

P25343	RV161_YEAST	Reduced viability upon starvation protein 161	1776363	Yeast mutant affected for viability upon nutrient starvation: characterization and cloning of the RVS161 gene.

Q05979	KYNU_YEAST	Kynureninase	12062417	Aerobic and anaerobic NAD+ metabolism in Saccharomyces cerevisiae.

Q99217	AMELX_HUMAN	Amelogenin, X isoform	1734713	The human enamel protein gene amelogenin is expressed from both the X and the Y chromosomes.

P38075	PDX3_YEAST	Pyridoxamine 5'-phosphate oxidase	7896706	Sterol uptake induced by an impairment of pyridoxal phosphate synthesis in Saccharomyces cerevisiae: cloning and sequencing of the PDX3 gene encoding pyridoxine (pyridoxamine) phosphate oxidase.

O43292	GPAA1_HUMAN	Glycosylphosphatidylinositol anchor attachment 1 protein	9468317	Molecular cloning of human homolog of yeast GAA1 which is required for attachment of glycosylphosphatidylinositols to proteins.

Q8N6D2	RN182_HUMAN	E3 ubiquitin-protein ligase RNF182	18298843	A novel brain-enriched E3 ubiquitin ligase RNF182 is up regulated in the brains of Alzheimer's patients and targets ATP6V0C for degradation.

O35864	CSN5_MOUSE	COP9 signalosome complex subunit 5	9707402	The COP9 complex is conserved between plants and mammals and is related to the 26S proteasome regulatory complex.

P47756	CAPZB_HUMAN	F-actin-capping protein subunit beta	7665558	Sequence analysis and chromosomal localization of human Cap Z. Conserved residues within the actin-binding domain may link Cap Z to gelsolin/severin and profilin protein families.

Q8LGH4	CUL4_ARATH	Cullin-4	16844902	Arabidopsis CULLIN4 forms an E3 ubiquitin ligase with RBX1 and the CDD complex in mediating light control of development.

O23147	ADPG1_ARATH	Polygalacturonase ADPG1	19168715	ARABIDOPSIS DEHISCENCE ZONE POLYGALACTURONASE1 (ADPG1), ADPG2, and QUARTET2 are polygalacturonases required for cell separation during reproductive development in Arabidopsis.

O59828	ALR1_SCHPO	Alanine racemase, catabolic	11244061	Functional characterization of alanine racemase from Schizosaccharomyces pombe: a eucaryotic counterpart to bacterial alanine racemase.

P29083	T2EA_HUMAN	General transcription factor IIE subunit 1	1956398	Structure and functional properties of human general transcription factor IIE.

Q92643	GPI8_HUMAN	GPI-anchor transamidase	10793132	Gaa1p and gpi8p are components of a glycosylphosphatidylinositol (GPI) transamidase that mediates attachment of GPI to proteins.

P38124	FLR1_YEAST	Fluconazole resistance protein 1	9235926	AP1-mediated multidrug resistance in Saccharomyces cerevisiae requires FLR1 encoding a transporter of the major facilitator superfamily.

P50874	ORC5_YEAST	Origin recognition complex subunit 5	7579692	The origin recognition complex in silencing, cell cycle progression, and DNA replication.

Q7KN62	TERA_DROME	Transitional endoplasmic reticulum ATPase TER94	10656772	Membrane fusion proteins are required for oskar mRNA localization in the Drosophila egg chamber.

P53630	BIOD_YEAST	Dethiobiotin synthetase	10333520	Characterization of the biotin biosynthesis pathway in Saccharomyces cerevisiae and evidence for a cluster containing BIO5, a novel gene involved in vitamer uptake.

Q811X5	EAF2_RAT	ELL-associated factor 2	12907652	Suppression of prostate tumor growth by U19, a novel testosterone- regulated apoptosis inducer.

Q96A11	G3ST3_HUMAN	Galactose-3-O-sulfotransferase 3	11323440	Molecular cloning and expression of a novel human beta-Gal-3-O- sulfotransferase that acts preferentially on N-acetyllactosamine in N- and O-glycans.

Q9VS59	AKIRN_DROME	Akirin	18066067	Akirins are highly conserved nuclear proteins required for NF-kappaB- dependent gene expression in Drosophila and mice.

Q04746	KAR5_YEAST	Nuclear fusion protein KAR5	9382856	KAR5 encodes a novel pheromone-inducible protein required for homotypic nuclear fusion.

Q9SEU6	TRXM4_ARATH	Thioredoxin M4, chloroplastic	19631646	Redox regulation of chloroplastic glucose-6-phosphate dehydrogenase: a new role for f-type thioredoxin.

Q8K4Y7	CANT1_RAT	Soluble calcium-activated nucleotidase 1	12167635	Cloning, expression, and functional characterization of a Ca2+- dependent endoplasmic reticulum nucleoside diphosphatase.

Q9NR28	DBLOH_HUMAN	Diablo homolog, mitochondrial	10950947	Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway.

Q9NPI9	IRK16_HUMAN	Inward rectifier potassium channel 16	11060447	The human inward rectifier K(+) channel subunit kir5.1 (KCNJ16) maps to chromosome 17q25 and is expressed in kidney and pancreas.

Q9V730	EXT1_DROME	Exostosin-1	9665133	Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion.

O36022	MNN9_SCHPO	Mannan polymerase complex subunit mnn9	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O80690	BGL46_ARATH	Beta-glucosidase 46	16814332	Arabidopsis thaliana beta-glucosidases BGLU45 and BGLU46 hydrolyse monolignol glucosides.

P40306	PSB10_HUMAN	Proteasome subunit beta type-10	8666937	Newly identified pair of proteasomal subunits regulated reciprocally by interferon gamma.

Q9Y624	JAM1_HUMAN	Junctional adhesion molecule A	10395639	Combined treatment of TNF-alpha and IFN-gamma causes redistribution of junctional adhesion molecule in human endothelial cells.

Q03529	SCS7_YEAST	Ceramide very long chain fatty acid hydroxylase SCS7	16652392	Mass spectrometry-based profiling of phospholipids and sphingolipids in extracts from Saccharomyces cerevisiae.

Q13838	UAP56_HUMAN	Spliceosome RNA helicase BAT1	15998806	Recruitment of the human TREX complex to mRNA during splicing.

P32249	GP183_HUMAN	G-protein coupled receptor 183	8383238	Epstein-Barr virus-induced genes: first lymphocyte-specific G protein-coupled peptide receptors.

Q96GD4	AURKB_HUMAN	Serine/threonine-protein kinase 12	18591255	A survivin-ran complex regulates spindle formation in tumor cells.

P60008	HILS1_HUMAN	Spermatid-specific linker histone H1-like protein	12920187	HILS1 is a spermatid-specific linker histone H1-like protein implicated in chromatin remodeling during mammalian spermiogenesis.

P11926	DCOR_HUMAN	Ornithine decarboxylase	2317811	Expression of human chromosome 2 ornithine decarboxylase gene in ornithine decarboxylase-deficient Chinese hamster ovary cells.

Q9NZN3	EHD3_HUMAN	EH domain-containing protein 3	10673336	EHD2, EHD3, and EHD4 encode novel members of a highly conserved family of EH domain-containing proteins.

Q8VHT8	TF3A_RAT	Transcription factor IIIA	11814676	cDNA cloning, DNA binding, and evolution of mammalian transcription factor IIIA.

P25580	PBN1_YEAST	Protein PBN1	15635094	Mammalian PIG-X and yeast Pbn1p are the essential components of glycosylphosphatidylinositol-mannosyltransferase I.

O70279	DGC14_MOUSE	Protein DGCR14	9499415	ES2, a gene deleted in DiGeorge syndrome, encodes a nuclear protein and is expressed during early mouse development, where it shares an expression domain with a Goosecoid-like gene.

P62826	RAN_HUMAN	GTP-binding nuclear protein Ran	1961752	Mitotic regulator protein RCC1 is complexed with a nuclear ras- related polypeptide.

P81451	ATP19_YEAST	ATP synthase subunit K, mitochondrial	9857174	Yeast mitochondrial F1F0-ATPase exists as a dimer: identification of three dimer-specific subunits.

P78545	ELF3_HUMAN	ETS-related transcription factor Elf-3	10773884	Dual function of the epithelial specific ets transcription factor, ELF3, in modulating differentiation.

Q9QZL6	UBP21_MOUSE	Ubiquitin carboxyl-terminal hydrolase 21	18172164	Deubiquitylation of histone H2A activates transcriptional initiation via trans-histone cross-talk with H3K4 di- and trimethylation.

Q01989	MYS9_DROME	Myosin heavy chain 95F	1429838	An unconventional myosin heavy chain gene from Drosophila melanogaster.

P13598	ICAM2_HUMAN	Intercellular adhesion molecule 2	2497351	Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1.

Q13547	HDAC1_HUMAN	Histone deacetylase 1	8646880	Isolation and mapping of a human gene (RPD3L1) that is homologous to RPD3, a transcription factor in Saccharomyces cerevisiae.

P02693	FABPI_RAT	Fatty acid-binding protein, intestinal	3840724	Analyzing the structures, functions and evolution of two abundant gastrointestinal fatty acid binding proteins with recombinant DNA and computational techniques.

P02919	PBPB_ECOLI	Penicillin-binding protein 1B	10564478	The catalytic, glycosyl transferase and acyl transferase modules of the cell wall peptidoglycan-polymerizing penicillin-binding protein 1b of Escherichia coli.

P32903	PMP1_YEAST	Plasma membrane ATPase proteolipid 1	1532582	Purification and complete sequence of a small proteolipid associated with the plasma membrane H(+)-ATPase of Saccharomyces cerevisiae.

Q9IA88	SIK2_CHICK	Serine/threonine-protein kinase SIK2	11027514	The new serine-threonine kinase, Qik, is a target of the Qin oncogene.

P38909	CYC2_YEAST	Cytochrome c mitochondrial import factor CYC2	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q8CFN5	MEF2C_MOUSE	Myocyte-specific enhancer factor 2C	9162005	Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C.

Q91ZD6	EAF2_MOUSE	ELL-associated factor 2	12761297	Identification of a novel tissue-specific transcriptional activator FESTA as a protein that interacts with the transcription elongation factor S-II.

P27933	AMY3D_ORYSJ	Alpha-amylase isozyme 3D	2263460	Structural organization and differential expression of rice alpha- amylase genes.

Q3UXZ9	KDM5A_MOUSE	Lysine-specific demethylase 5A	20064375	Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells.

P10834	PET54_YEAST	Protein PET54	2548921	The PET54 gene of Saccharomyces cerevisiae: characterization of a nuclear gene encoding a mitochondrial translational activator and subcellular localization of its product.

P22353	RM08_YEAST	54S ribosomal protein L8, mitochondrial	12392552	Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components.

Q99487	PAFA2_HUMAN	Platelet-activating factor acetylhydrolase 2, cytoplasmic	8955149	cDNA cloning and expression of intracellular platelet-activating factor (PAF) acetylhydrolase II. Its homology with plasma PAF acetylhydrolase.

Q8VSC3	IPA9_SHIFL	E3 ubiquitin-protein ligase ipaH9.8	11418613	Shigella protein IpaH(9.8) is secreted from bacteria within mammalian cells and transported to the nucleus.

P25300	BUD5_YEAST	Bud site selection protein 5	1905981	Yeast BUD5, encoding a putative GDP-GTP exchange factor, is necessary for bud site selection and interacts with bud formation gene BEM1.

Q9VXY2	MADD_DROME	MAP kinase-activating death domain protein	10798391	A genome-wide search for synaptic vesicle cycle proteins in Drosophila.

Q9UKV5	AMFR2_HUMAN	E3 ubiquitin-protein ligase AMFR	19103148	CYP3A4 ubiquitination by gp78 (the tumor autocrine motility factor receptor, AMFR) and CHIP E3 ligases.

P21784	RAG2_MOUSE	V(D)J recombination-activating protein 2	2360047	RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination.

Q62782	PHX2A_RAT	Paired mesoderm homeobox protein 2A	8613746	A homeodomain protein selectively expressed in noradrenergic tissue regulates transcription of neurotransmitter biosynthetic genes.

Q923E4	SIRT1_MOUSE	NAD-dependent deacetylase sirtuin-1	12482959	The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis.

P87232	RM04_SCHPO	54S ribosomal protein L4, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O95407	TNF6B_HUMAN	Tumor necrosis factor receptor superfamily member 6B	10318773	A newly identified member of tumor necrosis factor receptor superfamily (TR6) suppresses LIGHT-mediated apoptosis.

P23965	D3D2_RAT	3,2-trans-enoyl-CoA isomerase, mitochondrial	15883186	Domain swapping in the low-similarity isomerase/hydratase superfamily: the crystal structure of rat mitochondrial delta3, delta2-enoyl-CoA isomerase.

P25336	MSH3_YEAST	DNA mismatch repair protein MSH3	16702432	Analysis of the proteins involved in the in vivo repair of base-base mismatches and four-base loops formed during meiotic recombination in the yeast Saccharomyces cerevisiae.

P51652	AKC1H_RAT	Aldo-keto reductase family 1 member C18	8194472	Identification of a major prolactin-regulated protein as 20 alpha- hydroxysteroid dehydrogenase: coordinate regulation of its activity, protein content, and messenger ribonucleic acid expression.

Q13043	STK4_HUMAN	Serine/threonine-protein kinase 4	7665586	Cloning and characterization of a human protein kinase with homology to Ste20.

Q03052	PO3F1_HUMAN	POU domain, class 3, transcription factor 1	8451175	The human Oct-6 POU transcription factor lacks the first 50 amino acids of its murine counterpart.

P35710	SOX5_MOUSE	Transcription factor SOX-5	9755172	A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene.

Q42371	ERECT_ARATH	LRR receptor-like serine/threonine-protein kinase ERECTA	16002616	Stomatal patterning and differentiation by synergistic interactions of receptor kinases.

P36561	COBS_ECOLI	Cobalamin synthase	7592411	The cobalamin (coenzyme B12) biosynthetic genes of Escherichia coli.

Q8RXD6	BRE1A_ARATH	E3 ubiquitin-protein ligase BRE1-like 1	17329563	The absence of histone H2B monoubiquitination in the Arabidopsis hub1 (rdo4) mutant reveals a role for chromatin remodeling in seed dormancy.

P52097	TILS_ECOLI	tRNA(Ile)-lysidine synthase	14527414	An RNA-modifying enzyme that governs both the codon and amino acid specificities of isoleucine tRNA.

Q13610	PWP1_HUMAN	Periodic tryptophan protein 1 homolog	7828893	Cloning of a cDNA encoding a novel human nuclear phosphoprotein belonging to the WD-40 family.

P26572	MGAT1_HUMAN	Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	1702225	Cloning and expression of N-acetylglucosaminyltransferase I, the medial Golgi transferase that initiates complex N-linked carbohydrate formation.

Q9Y6N3	CLCA3_HUMAN	Calcium-activated chloride channel regulator family member 3	10095065	Molecular cloning and biochemical characterization of a truncated, secreted member of the human family of Ca2+-activated Cl- channels.

Q9UTC0	ZYM1_SCHPO	Metallothionein zym1	12050156	Surplus zinc is handled by Zym1 metallothionein and Zhf endoplasmic reticulum transporter in Schizosaccharomyces pombe.

P49282	NRAM2_MOUSE	Natural resistance-associated macrophage protein 2	15849611	Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver.

P36576	ARRC_RAT	Arrestin-C	8308033	Cone arrestin identified by targeting expression of a functional family.

P91799	IM25_SCHJA	25 kDa integral membrane protein	9370241	A new member of the transmembrane 4 superfamily (TM4SF) of proteins from schistosomes, expressed by larval and adult Schistosoma japonicum.

O15379	HDAC3_HUMAN	Histone deacetylase 3	11006275	Receptor-interacting protein 140 directly recruits histone deacetylases for gene silencing.

Q03479	MYOE_DICDI	Myosin IE heavy chain	12032065	Crystal structure of the motor domain of a class-I myosin.

Q05787	HRD3_YEAST	ERAD-associated E3 ubiquitin-protein ligase component HRD3	16873066	Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins.

Q9Z144	LEG2_RAT	Galectin-2	9882446	Identification and cloning of rat galectin-2: expression is predominantly in epithelial cells of the stomach.

Q8RY83	PUP13_ARATH	Probable purine permease 13	10662864	A new family of high-affinity transporters for adenine, cytosine, and purine derivatives in Arabidopsis.

Q86XK2	FBX11_HUMAN	F-box only protein 11	17098746	FBXO11 promotes the neddylation of p53 and inhibits its transcriptional activity.

Q9R0Q1	SYTL4_MOUSE	Synaptotagmin-like protein 4	11773082	The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain.

P53858	BNI4_YEAST	Protein BNI4	9314530	A septin-based hierarchy of proteins required for localized deposition of chitin in the Saccharomyces cerevisiae cell wall.

P34802	GGPP1_ARATH	Geranylgeranyl pyrophosphate synthase 1, chloroplastic	10759500	Five geranylgeranyl diphosphate synthases expressed in different organs are localized into three subcellular compartments in Arabidopsis.

Q03957	CTK1_YEAST	CTD kinase subunit alpha	7565723	The yeast carboxyl-terminal repeat domain kinase CTDK-I is a divergent cyclin-cyclin-dependent kinase complex.

Q24573	DRI_DROME	Protein dead ringer	8622680	Characterization of the dead ringer gene identifies a novel, highly conserved family of sequence-specific DNA-binding proteins.

O74731	DUS2_SCHPO	tRNA-dihydrouridine synthase 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O60244	MED14_HUMAN	Mediator of RNA polymerase II transcription subunit 14	11867769	The TRAP/Mediator coactivator complex interacts directly with estrogen receptors alpha and beta through the TRAP220 subunit and directly enhances estrogen receptor function in vitro.

P07213	TOM70_YEAST	Mitochondrial import receptor subunit TOM70	11054285	The mitochondrial import receptor Tom70: identification of a 25 kDa core domain with a specific binding site for preproteins.

P48201	AT5G3_HUMAN	ATP synthase lipid-binding protein, mitochondrial	7698763	Sequence analysis and mapping of a novel human mitochondrial ATP synthase subunit 9 cDNA (ATP5G3).

P0C187	PNTAB_RHORU	NAD(P) transhydrogenase subunit alpha part 2	7844118	Energy-transducing nicotinamide nucleotide transhydrogenase: nucleotide sequences of the genes and predicted amino acid sequences of the subunits of the enzyme from Rhodospirillum rubrum.

O94279	MGDP1_SCHPO	Putative magnesium-dependent phosphatase P8B7.31	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9ESL4	MLTK_MOUSE	Mitogen-activated protein kinase kinase kinase MLT	11042189	Identification and characterization of a novel MAP kinase kinase kinase, MLTK.

P18238	ADT3_YEAST	ADP,ATP carrier protein 3	2165073	A third ADP/ATP translocator gene in yeast.

Q55CS9	ATPB_DICDI	ATP synthase subunit beta, mitochondrial	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

Q04839	GFD1_YEAST	mRNA transport factor GFD1	10523319	Rat8p/Dbp5p is a shuttling transport factor that interacts with Rat7p/Nup159p and Gle1p and suppresses the mRNA export defect of xpo1- 1 cells.

Q62696	DLG1_RAT	Disks large homolog 1	9786987	Localization of postsynaptic density-93 to dendritic microtubules and interaction with microtubule-associated protein 1A.

Q80UM3	NAA15_MOUSE	N-alpha-acetyltransferase 15, NatA auxiliary subunit	12888564	An evolutionarily conserved N-terminal acetyltransferase complex associated with neuronal development.

B9TSP7	FACR6_ARATH	Fatty acyl-CoA reductase 6, chloroplastic	19062129	Functional expression of five Arabidopsis fatty acyl-CoA reductase genes in Escherichia coli.

P40515	FIS1_YEAST	Mitochondria fission 1 protein	11038182	Mdv1p is a WD repeat protein that interacts with the dynamin-related GTPase, Dnm1p, to trigger mitochondrial division.

Q00578	RAD25_YEAST	DNA repair helicase RAD25	8631896	Reconstitution of TFIIH and requirement of its DNA helicase subunits, Rad3 and Rad25, in the incision step of nucleotide excision repair.

Q9H900	ZWILC_HUMAN	Protein zwilch homolog	12686595	Zwilch, a new component of the ZW10/ROD complex required for kinetochore functions.

Q96WL3	URE2_CANAL	Protein URE2	12177423	Conservation of a portion of the S. cerevisiae Ure2p prion domain that interacts with the full-length protein.

P37238	PPARG_MOUSE	Peroxisome proliferator-activated receptor gamma	18719582	PRDM16 controls a brown fat/skeletal muscle switch.

P49279	NRAM1_HUMAN	Natural resistance-associated macrophage protein 1	8537108	Identification of natural resistance-associated macrophage protein in peripheral blood lymphocytes.

Q9GN62	PAR4_CAEEL	Serine/threonine-protein kinase par-4	10704392	The Caenorhabditis elegans par-4 gene encodes a putative serine- threonine kinase required for establishing embryonic asymmetry.

O35147	BAD_RAT	Bcl2 antagonist of cell death	11161472	Functional characterization of two splice variants of rat BAD and their interaction with Bcl-w in sympathetic neurons.

Q99MS8	TPGS1_MOUSE	Tubulin polyglutamylase complex subunit 1	12242242	Mutation of a novel gene results in abnormal development of spermatid flagella, loss of intermale aggression and reduced body fat in mice.

O70343	PRGC1_MOUSE	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha	14744933	Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK.

P38335	MTC4_YEAST	Maintenance of telomere capping protein 4	14562095	Global analysis of protein localization in budding yeast.

Q9BY76	ANGL4_HUMAN	Angiopoietin-related protein 4	10698685	Hepatic expression, synthesis and secretion of a novel fibrinogen/angiopoietin-related protein that prevents endothelial-cell apoptosis.

P40568	DSN1_YEAST	Kinetochore-associated protein DSN1	14657030	Nsl1p is essential for the establishment of bipolarity and the localization of the Dam-Duo complex.

Q9Z0H4	CELF2_MOUSE	CUGBP Elav-like family member 2	11158314	The CELF family of RNA binding proteins is implicated in cell- specific and developmentally regulated alternative splicing.

Q9Y6I4	UBP3_HUMAN	Ubiquitin carboxyl-terminal hydrolase 3	10480896	Characterization and chromosomal localization of USP3, a novel human ubiquitin-specific protease.

Q9H1Y0	ATG5_HUMAN	Autophagy protein 5	9852036	A new protein conjugation system in human. The counterpart of the yeast Apg12p conjugation system essential for autophagy.

Q9H1K1	ISCU_HUMAN	Iron-sulfur cluster assembly enzyme ISCU, mitochondrial	8875867	A modular domain of NifU, a nitrogen fixation cluster protein, is highly conserved in evolution.

Q8T045	RUMI_DROME	O-glucosyltransferase rumi	18243100	Rumi is a CAP10 domain glycosyltransferase that modifies Notch and is required for Notch signaling.

O93235	CIRBA_XENLA	Cold-inducible RNA-binding protein A	9602141	XCIRP (Xenopus homolog of cold-inducible RNA-binding protein) is expressed transiently in developing pronephros and neural tissue.

P32256	TBB_DICDI	Tubulin beta chain	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

Q5ZPR3	CD276_HUMAN	CD276 antigen	18650384	Triggering receptor expressed on myeloid cell-like transcript 2 (TLT- 2) is a counter-receptor for B7-H3 and enhances T cell responses.

P24896	NU5M_CAEEL	NADH-ubiquinone oxidoreductase chain 5	1551572	The mitochondrial genomes of two nematodes, Caenorhabditis elegans and Ascaris suum.

P35999	PMIP_YEAST	Mitochondrial intermediate peptidase	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

O00453	LST1_HUMAN	Leukocyte-specific transcript 1 protein	11478849	Functional analysis of B144/LST1: a gene in the tumor necrosis factor cluster that induces formation of long filopodia in eukaryotic cells.

Q9W3W5	WIF1_DROME	Protein shifted	15691766	Shifted, the Drosophila ortholog of wnt inhibitory factor-1, controls the distribution and movement of hedgehog.

O73689	ZIC1_XENLA	Zinc finger protein ZIC 1	9435279	Xenopus Zic-related-1 and Sox-2, two factors induced by chordin, have distinct activities in the initiation of neural induction.

O43526	KCNQ2_HUMAN	Potassium voltage-gated channel subfamily KQT member 2	9677360	Functional expression of two KvLQT1-related potassium channels responsible for an inherited idiopathic epilepsy.

P16056	MET_MOUSE	Hepatocyte growth factor receptor	15314156	MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met.

O16850	FOXO_CAEEL	Forkhead box protein O	17276341	RLE-1, an E3 ubiquitin ligase, regulates C. elegans aging by catalyzing DAF-16 polyubiquitination.

Q10452	GSK3_SCHPO	Protein kinase gsk3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8R4F0	MCLN3_MOUSE	Mucolipin-3	12403827	Mutations in Mcoln3 associated with deafness and pigmentation defects in varitint-waddler (Va) mice.

P38251	RFC5_YEAST	Replication factor C subunit 5	11486023	Chl12 (Ctf18) forms a novel replication factor C-related complex and functions redundantly with Rad24 in the DNA replication checkpoint pathway.

Q96EB1	ELP4_HUMAN	Elongator complex protein 4	11818576	Human Elongator facilitates RNA polymerase II transcription through chromatin.

Q1PDW5	FTSH6_ARATH	ATP-dependent zinc metalloprotease FTSH 6, chloroplastic	14630971	Coordinated regulation and complex formation of yellow variegated1 and yellow variegated2, chloroplastic FtsH metalloproteases involved in the repair cycle of photosystem II in Arabidopsis thylakoid membranes.

Q9NQS3	PVRL3_HUMAN	Poliovirus receptor-related protein 3	19011627	The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.

O59834	FCYS_SCHPO	Probable cytosine deaminase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9S709	U2AFA_ARATH	Splicing factor U2af small subunit A	16407443	Molecular characterization and phylogeny of U2AF35 homologs in plants.

P22057	PTGDS_RAT	Prostaglandin-H2 D-isomerase	9188476	Lipocalin-type prostaglandin D synthase (beta-trace) is a newly recognized type of retinoid transporter.

A5WWC6	HSDL1_DANRE	Inactive hydroxysteroid dehydrogenase-like protein 1	19026618	Human and zebrafish hydroxysteroid dehydrogenase like 1 (HSDL1) proteins are inactive enzymes but conserved among species.

O08586	PTEN_MOUSE	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	10339565	PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway.

Q9S7W5	TCP13_ARATH	Transcription factor TCP13	11161017	Involvement of a nuclear-encoded basic helix-loop-helix protein in transcription of the light-responsive promoter of psbD.

P29717	EXG_CANAL	Glucan 1,3-beta-glucosidase	1789004	The major exoglucanase from Candida albicans: a non-glycosylated secretory monomer related to its counterpart from Saccharomyces cerevisiae.

O60131	YH7H_SCHPO	Uncharacterized transcriptional regulatory protein C16G5.17	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P32570	MED22_YEAST	Mediator of RNA polymerase II transcription subunit 22	16885025	Head module control of mediator interactions.

P38757	NEM1_YEAST	Nuclear envelope morphology protein 1	9822591	A novel complex of membrane proteins required for formation of a spherical nucleus.

O43087	KMS2_SCHPO	Karyogamy meiotic segregation protein 2	14655046	Two-hybrid search for proteins that interact with Sad1 and Kms1, two membrane-bound components of the spindle pole body in fission yeast.

Q8CCH7	FOG2_MOUSE	Zinc finger protein ZFPM2	10888889	A syndrome of tricuspid atresia in mice with a targeted mutation of the gene encoding Fog-2.

Q9D495	SYCE1_MOUSE	Synaptonemal complex central element protein 1	15944401	Two novel proteins recruited by synaptonemal complex protein 1 (SYCP1) are at the center of meiosis.

P13856	RSR1_YEAST	Ras-related protein RSR1	2690082	Multicopy suppression of the cdc24 budding defect in yeast by CDC42 and three newly identified genes including the ras-related gene RSR1.

Q9ES64	USH1C_MOUSE	Harmonin	15461667	Harp (harmonin-interacting, ankyrin repeat-containing protein), a novel protein that interacts with harmonin in epithelial tissues.

Q9GZV1	ANKR2_HUMAN	Ankyrin repeat domain-containing protein 2	11444853	Characterization of human skeletal muscle Ankrd2.

P54644	KRAC_DICDI	RAC family serine/threonine-protein kinase homolog	10205164	Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium.

P85061	PA2A3_ACASS	Phospholipase A2, acanmyotoxin-3	16242671	Isolation and characterisation of acanmyotoxin-2 and acanmyotoxin-3, myotoxins from the venom of the death adder Acanthophis sp. Seram.

Q6P2D8	XRRA1_HUMAN	X-ray radiation resistance-associated protein 1	12908878	Molecular cloning, genomic characterization and over-expression of a novel gene, XRRA1, identified from human colorectal cancer cell HCT116Clone2_XRR and macaque testis.

Q9BIR7	HSP75_DROME	Major heat shock 70 kDa protein Bc	6777045	Sequence of three copies of the gene for the major Drosophila heat shock induced protein and their flanking regions.

P40468	TAO3_YEAST	Cell morphogenesis protein PAG1	11854408	Pag1p, a novel protein associated with protein kinase Cbk1p, is required for cell morphogenesis and proliferation in Saccharomyces cerevisiae.

P40363	SFGH_YEAST	S-formylglutathione hydrolase	10427036	Purification and properties of an esterase from the yeast Saccharomyces cerevisiae and identification of the encoding gene.

P32418	NAC1_HUMAN	Sodium/calcium exchanger 1	1374913	Molecular cloning and characterization of the human cardiac Na+/Ca2+ exchanger cDNA.

O94737	MAPK1_PNECA	Mitogen-activated protein kinase 1	10889467	Mkp1 of Pneumocystis carinii associates with the yeast transcription factor Rlm1 via a mechanism independent of the activation state.

O70280	WFDC1_RAT	WAP four-disulfide core domain protein 1	7665628	Purification of a novel protein (ps20) from urogenital sinus mesenchymal cells with growth inhibitory properties in vitro.

P38782	MED6_YEAST	Mediator of RNA polymerase II transcription subunit 6	16885025	Head module control of mediator interactions.

P87014	MAM4_SCHPO	Protein-S-isoprenylcysteine O-methyltransferase	9032282	Genes encoding farnesyl cysteine carboxyl methyltransferase in Schizosaccharomyces pombe and Xenopus laevis.

P36510	UD2A1_RAT	UDP-glucuronosyltransferase 2A1	1900353	Odorant signal termination by olfactory UDP glucuronosyl transferase.

O94733	YQ61_SCHPO	Uncharacterized protein C191.01	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P25368	RRP7_YEAST	Ribosomal RNA-processing protein 7	17515605	The 90S preribosome is a multimodular structure that is assembled through a hierarchical mechanism.

Q15648	MED1_HUMAN	Mediator of RNA polymerase II transcription subunit 1	11867769	The TRAP/Mediator coactivator complex interacts directly with estrogen receptors alpha and beta through the TRAP220 subunit and directly enhances estrogen receptor function in vitro.

P06733	ENOA_HUMAN	Alpha-enolase	3529090	Molecular cloning and nucleotide sequence of a full-length cDNA for human alpha enolase.

Q9LDR9	EXP10_ARATH	Expansin-A10	10931949	Altered expression of expansin modulates leaf growth and pedicel abscission in Arabidopsis thaliana.

P17695	GLRX2_YEAST	Glutaredoxin-2, mitochondrial	11958675	Two isoforms of Saccharomyces cerevisiae glutaredoxin 2 are expressed in vivo and localize to different subcellular compartments.

Q62661	HBP1_RAT	HMG box-containing protein 1	7937077	Expression cloning in K+ transport defective yeast and distribution of HBP1, a new putative HMG transcriptional regulator.

P54730	UBX4_YEAST	UBX domain-containing protein 4	14562095	Global analysis of protein localization in budding yeast.

P62701	RS4X_HUMAN	40S ribosomal protein S4, X isoform	2124517	Homologous ribosomal protein genes on the human X and Y chromosomes: escape from X inactivation and possible implications for Turner syndrome.

Q55EX9	Y8948_DICDI	Putative methyltransferase DDB_G0268948	19482547	Proteomic analysis of Legionella-containing phagosomes isolated from Dictyostelium.

P41597	CCR2_HUMAN	C-C chemokine receptor type 2	8995400	Organization and differential expression of the human monocyte chemoattractant protein 1 receptor gene. Evidence for the role of the carboxyl-terminal tail in receptor trafficking.

Q9Y5N1	HRH3_HUMAN	Histamine H3 receptor	10347254	Cloning and functional expression of the human histamine H3 receptor.

Q6P730	DAB2P_RAT	Disabled homolog 2-interacting protein	11812785	The mechanism of growth-inhibitory effect of DOC-2/DAB2 in prostate cancer. Characterization of a novel GTPase-activating protein associated with N-terminal domain of DOC-2/DAB2.

P51480	CD2A1_MOUSE	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2	7651726	Cloning and characterization of murine p16INK4a and p15INK4b genes.

P02790	HEMO_HUMAN	Hemopexin	3855550	Complete amino acid sequence of human hemopexin, the heme-binding protein of serum.

P59055	CSRN3_MOUSE	Cysteine/serine-rich nuclear protein 3	18291095	Taip2 is a novel cell death-related gene expressed in the brain during development.

Q923M1	MSRA_RAT	Peptide methionine sulfoxide reductase	11311146	Rat peptide methionine sulphoxide reductase: cloning of the cDNA, and down-regulation of gene expression and enzyme activity during aging.

Q12417	PRP46_YEAST	Pre-mRNA-splicing factor PRP46	12088152	Characterization of interactions among the Cef1p-Prp19p-associated splicing complex.

Q02725	VTC3_YEAST	Vacuolar transporter chaperone 3	11102525	New components of a system for phosphate accumulation and polyphosphate metabolism in Saccharomyces cerevisiae revealed by genomic expression analysis.

Q9VQE7	G23AA_DROME	Putative gustatory receptor 23a, isoforms A/C	10710312	Candidate taste receptors in Drosophila.

P53852	SYC_YEAST	Cysteinyl-tRNA synthetase	9523015	Cysteinyl-tRNA synthetase from Saccharomyces cerevisiae. Purification, characterization and assignment to the genomic sequence YNL247w.

Q9M7I7	CLH2_ARATH	Chlorophyllase-2, chloroplastic	10611389	Cloning of chlorophyllase, the key enzyme in chlorophyll degradation: finding of a lipase motif and the induction by methyl jasmonate.

Q15672	TWST1_HUMAN	Twist-related protein 1	8988166	Mutations in TWIST, a basic helix-loop-helix transcription factor, in Saethre-Chotzen syndrome.

Q8WYP5	ELYS_HUMAN	Protein ELYS	17098863	ELYS is a dual nucleoporin/kinetochore protein required for nuclear pore assembly and proper cell division.

Q14654	IRK11_HUMAN	ATP-sensitive inward rectifier potassium channel 11	15115830	Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6.2 and permanent neonatal diabetes.

Q8TAQ2	SMRC2_HUMAN	SWI/SNF complex subunit SMARCC2	12192000	REST repression of neuronal genes requires components of the hSWI.SNF complex.

P36383	CXG1_HUMAN	Gap junction gamma-1 protein	7966354	Molecular cloning of two human cardiac gap junction proteins, connexin40 and connexin45.

Q8BLA8	TRPA1_MOUSE	Transient receptor potential cation channel subfamily A member 1	12654248	ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures.

P27616	PUR7_YEAST	Phosphoribosylaminoimidazole-succinocarboxamide synthase	1756975	The Saccharomyces cerevisiae ADE1 gene: structure, overexpression and possible regulation by general amino acid control.

Q80UW2	FBX2_MOUSE	F-box only protein 2	15723043	Glycoprotein-specific ubiquitin ligases recognize N-glycans in unfolded substrates.

P35459	LY6D_MOUSE	Lymphocyte antigen 6D	19833765	Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development.

Q24266	BTD_DROME	Transcription factor btd	8259212	A Drosophila homologue of human Sp1 is a head-specific segmentation gene.

Q80ZG2	IP3KC_RAT	Inositol-trisphosphate 3-kinase C	12649294	Rat inositol 1,4,5-trisphosphate 3-kinase C is enzymatically specialized for basal cellular inositol trisphosphate phosphorylation and shuttles actively between nucleus and cytoplasm.

Q9FHD4	CRR58_ARATH	Cysteine-rich repeat secretory protein 58	12805588	Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis.

P01127	PDGFB_HUMAN	Platelet-derived growth factor subunit B	1661670	Two PDGF-B chain residues, arginine 27 and isoleucine 30, mediate receptor binding and activation.

Q03306	PKH3_YEAST	Serine/threonine-protein kinase PKH3	10567559	PDK1 homologs activate the Pkc1-mitogen-activated protein kinase pathway in yeast.

P52917	VPS4_YEAST	Vacuolar protein sorting-associated protein 4	16601096	Vta1p and Vps46p regulate the membrane association and ATPase activity of Vps4p at the yeast multivesicular body.

Q5U4X3	MEI3A_XENLA	Homeobox protein meis3-A	14660437	Xenopus Meis3 protein forms a hindbrain-inducing center by activating FGF/MAP kinase and PCP pathways.

Q9HBJ7	UBP29_HUMAN	Ubiquitin carboxyl-terminal hydrolase 29	10958632	Discovery of a novel, paternally expressed ubiquitin-specific processing protease gene through comparative analysis of an imprinted region of mouse chromosome 7 and human chromosome 19q13.4.

P14284	DPOZ_YEAST	DNA polymerase zeta catalytic subunit	16452144	Saccharomyces cerevisiae polymerase zeta functions in mitochondria.

Q5T4W7	ARTN_HUMAN	Artemin	9883723	Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex.

P27824	CALX_HUMAN	Calnexin	8055875	The molecular chaperones HSP28, GRP78, endoplasmin, and calnexin exhibit strikingly different levels in quiescent keratinocytes as compared to their proliferating normal and transformed counterparts: cDNA cloning and expression of calnexin.

Q9LVI4	TIF6B_ARATH	Protein TIFY 6B	17637675	The JAZ family of repressors is the missing link in jasmonate signalling.

Q02776	TIM50_YEAST	Mitochondrial import inner membrane translocase subunit TIM50	12437925	Tim50 is a subunit of the TIM23 complex that links protein translocation across the outer and inner mitochondrial membranes.

P0AFI2	PARC_ECOLI	DNA topoisomerase 4 subunit A	2170028	New topoisomerase essential for chromosome segregation in E. coli.

Q9UQ72	PSG11_HUMAN	Pregnancy-specific beta-1-glycoprotein 11	7794280	Characterization of cDNA encoding novel pregnancy-specific glycoprotein variants.

Q80U72	SCRIB_MOUSE	Protein scribble homolog	19458197	Scribble interacts with beta-catenin to localize synaptic vesicles to synapses.

Q9LX93	ATL55_ARATH	E3 ubiquitin-protein ligase RING1	18643987	RING1 E3 ligase localizes to plasma membrane lipid rafts to trigger FB1-induced programmed cell death in Arabidopsis.

Q12196	RIO1_YEAST	Serine/threonine-protein kinase RIO1	12612080	Late cytoplasmic maturation of the small ribosomal subunit requires RIO proteins in Saccharomyces cerevisiae.

Q99819	GDIR3_HUMAN	Rho GDP-dissociation inhibitor 3	9113980	RhoGDIgamma: a GDP-dissociation inhibitor for Rho proteins with preferential expression in brain and pancreas.

P18510	IL1RA_HUMAN	Interleukin-1 receptor antagonist protein	2139180	Purification, cloning, expression and biological characterization of an interleukin-1 receptor antagonist protein.

Q99661	KIF2C_HUMAN	Kinesin-like protein KIF2C	19632184	An EB1-binding motif acts as a microtubule tip localization signal.

P47942	DPYL2_RAT	Dihydropyrimidinase-related protein 2	7472434	TOAD-64, a gene expressed early in neuronal differentiation in the rat, is related to unc-33, a C. elegans gene involved in axon outgrowth.

Q10471	GALT2_HUMAN	Polypeptide N-acetylgalactosaminyltransferase 2	12438318	Initiation of O-glycan synthesis in IgA1 hinge region is determined by a single enzyme, UDP-N-acetyl-alpha-D-galactosamine:polypeptide N- acetylgalactosaminyltransferase 2.

O62090	PRY1_CAEEL	Axin-like protein pry-1	9834184	A Wnt signaling pathway controls hox gene expression and neuroblast migration in C. elegans.

O75154	RFIP3_HUMAN	Rab11 family-interacting protein 3	12470645	Rab11-FIP4 interacts with Rab11 in a GTP-dependent manner and its overexpression condenses the Rab11 positive compartment in HeLa cells.

P64943	PAFA_MYCTU	Pup--protein ligase	17082771	Identification of substrates of the Mycobacterium tuberculosis proteasome.

O95256	I18RA_HUMAN	Interleukin-18 receptor accessory protein	9792649	Cloning of a novel receptor subunit, AcPL, required for interleukin- 18 signaling.

Q8ND04	SMG8_HUMAN	Protein SMG8	19417104	SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay.

Q08490	SGO1_YEAST	Shugoshin	15637284	The centromeric protein Sgo1 is required to sense lack of tension on mitotic chromosomes.

Q9NY28	GALT8_HUMAN	Probable polypeptide N-acetylgalactosaminyltransferase 8	10767557	Molecular cloning of a novel human UDP-GalNAc:polypeptide N- acetylgalactosaminyltransferase, GalNAc-T8, and analysis as a candidate autosomal dominant hypophosphatemic rickets (ADHR) gene.

P38195	ECM13_YEAST	Protein ECM13	9335584	Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae.

O01498	STAM1_CAEEL	Signal transducing adapter molecule 1	17581863	STAM and Hrs down-regulate ciliary TRP receptors.

Q9NRI5	DISC1_HUMAN	Disrupted in schizophrenia 1 protein	19502360	Disc1 regulates granule cell migration in the developing hippocampus.

O95398	RPGF3_HUMAN	Rap guanine nucleotide exchange factor 3	10777494	Mechanism of regulation of the Epac family of cAMP-dependent RapGEFs.

P47169	ECM17_YEAST	Sulfite reductase [NADPH] subunit beta	6751400	Studies on yeast sulfite reductase. IV. Structure and steady-state kinetics.

P60215	SC54_TITCA	Toxin Tc54	15025998	Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

Q21443	LMN1_CAEEL	Lamin-1	12684533	MAN1 and emerin have overlapping function(s) essential for chromosome segregation and cell division in Caenorhabditis elegans.

P37680	SGBE_ECOLI	L-ribulose-5-phosphate 4-epimerase sgbE	10913097	Role of the yiaR and yiaS genes of Escherichia coli in metabolism of endogenously formed L-xylulose.

P40081	MGDP1_YEAST	Putative magnesium-dependent phosphatase YER134C	14562095	Global analysis of protein localization in budding yeast.

Q9H8T0	AKTIP_HUMAN	AKT-interacting protein	18799622	An FTS/Hook/p107(FHIP) complex interacts with and promotes endosomal clustering by the homotypic vacuolar protein sorting complex.

P18887	XRCC1_HUMAN	DNA repair protein XRCC1	15044383	Aprataxin, a novel protein that protects against genotoxic stress.

Q42546	DPNP1_ARATH	SAL1 phosphatase	11485991	FIERY1 encoding an inositol polyphosphate 1-phosphatase is a negative regulator of abscisic acid and stress signaling in Arabidopsis.

Q96RU7	TRIB3_HUMAN	Tribbles homolog 3	12743605	SKIP3, a novel Drosophila tribbles ortholog, is overexpressed in human tumors and is regulated by hypoxia.

Q16570	DUFFY_HUMAN	Duffy antigen/chemokine receptor	10570183	Emergence of FY*A(null) in a Plasmodium vivax-endemic region of Papua New Guinea.

Q8QGV6	NLK2_XENLA	Serine/threonine-protein kinase NLK2	12875653	Negative regulation of Wnt signalling by HMG2L1, a novel NLK-binding protein.

O65718	CNGC2_ARATH	Cyclic nucleotide-gated ion channel 2	10341447	Characterisation of a novel gene family of putative cyclic nucleotide- and calmodulin-regulated ion channels in Arabidopsis thaliana.

O35293	CP2F2_RAT	Cytochrome P450 2F2	15509722	Bioactivation of the pulmonary toxicants naphthalene and 1- nitronaphthalene by rat CYP2F4.

O94361	YHOE_SCHPO	Uncharacterized acyltransferase C428.14	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P02750	A2GL_HUMAN	Leucine-rich alpha-2-glycoprotein	3856868	Periodicity of leucine and tandem repetition of a 24-amino acid segment in the primary structure of leucine-rich alpha 2-glycoprotein of human serum.

Q9VEU6	GCYDA_DROME	Soluble guanylate cyclase 89Da	15485853	Atypical soluble guanylyl cyclases in Drosophila can function as molecular oxygen sensors.

P03873	MBI2_YEAST	Cytochrome b mRNA maturase bI2	8670880	Replacement of two non-adjacent amino acids in the S.cerevisiae bi2 intron-encoded RNA maturase is sufficient to gain a homing- endonuclease activity.

Q9MBA1	CAO_ARATH	Chlorophyllide a oxygenase, chloroplastic	15805480	The N-terminal domain of chlorophyllide a oxygenase confers protein instability in response to chlorophyll b accumulation in Arabidopsis.

O15554	KCNN4_HUMAN	Intermediate conductance calcium-activated potassium channel protein 4	9407042	A novel gene, hKCa4, encodes the calcium-activated potassium channel in human T lymphocytes.

P35914	HMGCL_HUMAN	Hydroxymethylglutaryl-CoA lyase, mitochondrial	8440722	3-hydroxy-3-methylglutaryl coenzyme A lyase (HL). Cloning of human and chicken liver HL cDNAs and characterization of a mutation causing human HL deficiency.

Q14152	EIF3A_HUMAN	Eukaryotic translation initiation factor 3 subunit A	18599441	Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3.

O35251	VEGFD_RAT	Vascular endothelial growth factor D	11683876	Characterization of indolinones which preferentially inhibit VEGF-C- and VEGF-D-induced activation of VEGFR-3 rather than VEGFR-2.

Q0D840	TRXH1_ORYSJ	Thioredoxin H1	9599802	Rice phloem thioredoxin h has the capacity to mediate its own cell- to-cell transport through plasmodesmata.

P36552	HEM6_MOUSE	Coproporphyrinogen-III oxidase, mitochondrial	8407975	Coproporphyrinogen oxidase. Purification, molecular cloning, and induction of mRNA during erythroid differentiation.

O70405	ULK1_MOUSE	Serine/threonine-protein kinase ULK1	10624947	A mouse serine/threonine kinase homologous to C. elegans UNC51 functions in parallel fiber formation of cerebellar granule neurons.

P70658	CXCR4_MOUSE	C-X-C chemokine receptor type 4	18227060	Regulation of myoblast motility and fusion by the CXCR4-associated sialomucin, CD164.

P32491	MKK2_YEAST	MAP kinase kinase MKK2/SSP33	8386320	MKK1 and MKK2, which encode Saccharomyces cerevisiae mitogen- activated protein kinase-kinase homologs, function in the pathway mediated by protein kinase C.

Q8CGU1	CACO1_MOUSE	Calcium-binding and coiled-coil domain-containing protein 1	15383530	Role of the coiled-coil coactivator (CoCoA) in aryl hydrocarbon receptor-mediated transcription.

Q54RR8	RDEA_DICDI	Phosphorelay intermediate protein rdeA	9582274	Evidence that the RdeA protein is a component of a multistep phosphorelay modulating rate of development in Dictyostelium.

P61326	MGN_HUMAN	Protein mago nashi homolog	19410547	Disassembly of exon junction complexes by PYM.

Q9T014	SPA2_ARATH	Protein SPA1-RELATED 2	16854975	Arabidopsis SPA proteins regulate photoperiodic flowering and interact with the floral inducer CONSTANS to regulate its stability.

Q9NZI2	KCIP1_HUMAN	Kv channel-interacting protein 1	10676964	Modulation of A-type potassium channels by a family of calcium sensors.

Q02939	TFB2_YEAST	RNA polymerase II transcription factor B subunit 2	14500720	Revised subunit structure of yeast transcription factor IIH (TFIIH) and reconciliation with human TFIIH.

P46098	5HT3A_HUMAN	5-hydroxytryptamine receptor 3A	9950429	The 5-HT3B subunit is a major determinant of serotonin-receptor function.

Q84JG2	SWI3B_ARATH	SWI/SNF complex subunit SWI3B	19033529	HAB1-SWI3B interaction reveals a link between abscisic acid signaling and putative SWI/SNF chromatin-remodeling complexes in Arabidopsis.

Q12840	KIF5A_HUMAN	Kinesin heavy chain isoform 5A	7514426	Cloning and localization of a conventional kinesin motor expressed exclusively in neurons.

Q06411	SP382_YEAST	Pre-mRNA-splicing factor SPP382	16357217	Spliceosome disassembly catalyzed by Prp43 and its associated components Ntr1 and Ntr2.

P05067	A4_HUMAN	Amyloid beta A4 protein	10681545	Beta-amyloid(1-42) binds to alpha7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology.

Q6PUV4	CPLX2_HUMAN	Complexin-2	7553862	Complexins: cytosolic proteins that regulate SNAP receptor function.

Q8RXD3	AIP2_ARATH	E3 ubiquitin-protein ligase AIP2	15998807	The AIP2 E3 ligase acts as a novel negative regulator of ABA signaling by promoting ABI3 degradation.

Q07442	BDF2_YEAST	Bromodomain-containing factor 2	12620224	Different sensitivities of bromodomain factors 1 and 2 to histone H4 acetylation.

O74738	YH9D_SCHPO	SET domain-containing protein C1709.13c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O74542	YCV3_SCHPO	Uncharacterized aminotransferase C777.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q15075	EEA1_HUMAN	Early endosome antigen 1	11741531	Multivalent endosome targeting by homodimeric EEA1.

P06780	RHO1_YEAST	GTP-binding protein RHO1	15596542	Quantitative mass spectrometry reveals a role for the GTPase Rho1p in actin organization on the peroxisome membrane.

Q15633	TRBP2_HUMAN	RISC-loading complex subunit TARBP2	2011739	Characterization of a human TAR RNA-binding protein that activates the HIV-1 LTR.

Q61955	KLK8_MOUSE	Kallikrein-8	11880192	Extracellular serine protease neuropsin (KLK8) modulates neurite outgrowth and fasciculation of mouse hippocampal neurons in culture.

Q08748	YO296_YEAST	Uncharacterized protein YOR296W	14562095	Global analysis of protein localization in budding yeast.

Q9Z2N6	CK2N2_RAT	Calcium/calmodulin-dependent protein kinase II inhibitor 2	9724800	Characterization of a calmodulin kinase II inhibitor protein in brain.

P0A8Q6	CLPS_ECOLI	ATP-dependent Clp protease adapter protein ClpS	12235156	Crystal structure of the heterodimeric complex of the adaptor, ClpS, with the N-domain of the AAA+ chaperone, ClpA.

P15923	TFE2_HUMAN	Transcription factor E2-alpha	2105528	Two distinct transcription factors that bind the immunoglobulin enhancer microE5/kappa 2 motif.

P04466	MLRS_RAT	Myosin regulatory light chain 2, skeletal muscle isoform	6179945	Cloning and characterization of cDNA sequences corresponding to myosin light chains 1, 2, and 3, troponin-C, troponin-T, alpha- tropomyosin, and alpha-actin.

Q8IQG1	MOB2_DROME	Mps one binder kinase activator-like 2	15975907	Drosophila Mob family proteins interact with the related tricornered (Trc) and warts (Wts) kinases.

Q9UT36	GLO21_SCHPO	Probable hydroxyacylglutathione hydrolase C824.07	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P43063	CDK1_CANAL	Cell division control protein 28	7830719	Molecular cloning and analysis of CDC28 and cyclin homologues from the human fungal pathogen Candida albicans.

P40020	FIR1_YEAST	Factor interacting with REF2	14562095	Global analysis of protein localization in budding yeast.

Q6K846	IAA9_ORYSJ	Auxin-responsive protein IAA9	16200395	Structure and expression analysis of early auxin-responsive Aux/IAA gene family in rice (Oryza sativa).

P56539	CAV3_HUMAN	Caveolin-3	17060380	Mutant caveolin-3 induces persistent late sodium current and is associated with long-QT syndrome.

P0A7Z0	RPIA_ECOLI	Ribose-5-phosphate isomerase A	8366047	Escherichia coli rpiA gene encoding ribose phosphate isomerase A.

O43264	ZW10_HUMAN	Centromere/kinetochore protein zw10 homolog	15029241	Implication of ZW10 in membrane trafficking between the endoplasmic reticulum and Golgi.

Q91399	ID3A_XENLA	DNA-binding protein inhibitor ID-3-A	15769946	To proliferate or to die: role of Id3 in cell cycle progression and survival of neural crest progenitors.

P32361	IRE1_YEAST	Serine/threonine-protein kinase/endoribonuclease IRE1	8358794	A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus.

Q9I8A3	HEY1_XENLA	Hairy/enhancer-of-split related with YRPW motif protein 1	14648848	Identification of BOIP, a novel cDNA highly expressed during spermatogenesis that encodes a protein interacting with the orange domain of the hairy-related transcription factor HRT1/Hey1 in Xenopus and mouse.

Q5I2D0	RIPP_BRABE	Protein ripply	16326386	Groucho-associated transcriptional repressor ripply1 is required for proper transition from the presomitic mesoderm to somites.

Q99731	CCL19_HUMAN	C-C motif chemokine 19	9153236	Molecular cloning of a novel human CC chemokine EBI1-ligand chemokine that is a specific functional ligand for EBI1, CCR7.

P20133	PGTB2_YEAST	Geranylgeranyl transferase type-2 subunit beta	8232542	Bet2p and Mad2p are components of a prenyltransferase that adds geranylgeranyl onto Ypt1p and Sec4p.

P30520	PURA2_HUMAN	Adenylosuccinate synthetase isozyme 2	1592113	Cloning and characterization of the cDNA encoding human adenylosuccinate synthetase.

O15169	AXN1_HUMAN	Axin-1	16601693	Axin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia.

Q91XJ0	CREST_RAT	Calcium-responsive transcription coactivator	15866867	A multifunctional domain of the calcium-responsive transactivator (CREST) that inhibits dendritic growth in cultured neurons.

Q9UQ80	PA2G4_HUMAN	Proliferation-associated protein 2G4	11268000	Ebp1, an ErbB-3 binding protein, interacts with Rb and affects Rb transcriptional regulation.

Q8R400	ADIG_MOUSE	Adipogenin	16132694	Up-regulation of adipogenin, an adipocyte plasma transmembrane protein, during adipogenesis.

P50582	HSK1_SCHPO	Cell cycle serine/threonine-protein kinase hsk1	11359920	Regulation of initiation of S phase, replication checkpoint signaling, and maintenance of mitotic chromosome structures during S phase by Hsk1 kinase in the fission yeast.

Q8K1N4	SPAS2_MOUSE	Spermatogenesis-associated serine-rich protein 2	11944913	Identification of a novel protein p59(scr), which is expressed at specific stages of mouse spermatogenesis.

P60228	EIF3E_HUMAN	Eukaryotic translation initiation factor 3 subunit E	18599441	Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3.

Q9UTF0	YIN2_SCHPO	SERF-like protein C1705.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P85001	CE290_DANRE	Centrosomal protein of 290 kDa	16682973	The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4.

Q03267	IKZF1_MOUSE	DNA-binding protein Ikaros	15767674	Ikaros SUMOylation: switching out of repression.

Q96524	CRY2_ARATH	Cryptochrome-2	11089975	Functional interaction of phytochrome B and cryptochrome 2.

P17214	EST1_YEAST	Telomere elongation protein EST1	2655926	A mutant with a defect in telomere elongation leads to senescence in yeast.

Q09511	RSP4_CAEEL	Probable splicing factor, arginine/serine-rich 4	10747030	Functional characterization of SR and SR-related genes in Caenorhabditis elegans.

Q9ER42	BARX1_MOUSE	Homeobox protein BarH-like 1	15809042	The stomach mesenchymal transcription factor Barx1 specifies gastric epithelial identity through inhibition of transient Wnt signaling.

Q8MNV0	SPAST_CAEEL	Probable spastin homolog spas-1	18202664	Structural basis of microtubule severing by the hereditary spastic paraplegia protein spastin.

Q9P7H5	COX24_SCHPO	Mitochondrial mRNA-processing protein cox24	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q60870	REEP5_MOUSE	Receptor expression-enhancing protein 5	19665976	A class of dynamin-like GTPases involved in the generation of the tubular ER network.

Q9UQ84	EXO1_HUMAN	Exonuclease 1	11809771	Human exonuclease I is required for 5' and 3' mismatch repair.

Q9M0V3	DDB1A_ARATH	DNA damage-binding protein 1a	12225661	De-etiolated 1 and damaged DNA binding protein 1 interact to regulate Arabidopsis photomorphogenesis.

P97318	DAB1_MOUSE	Disabled homolog 1	9009273	Mouse disabled (mDab1): a Src binding protein implicated in neuronal development.

Q8K203	NEIL3_MOUSE	Endonuclease 8-like 3	16428305	Hematopoietic tissue-specific expression of mouse Neil3 for endonuclease VIII-like protein.

P54733	CCNE_DROME	G1/S-specific cyclin-E	8187637	A Drosophila G1-specific cyclin E homolog exhibits different modes of expression during embryogenesis.

P25846	MSH1_YEAST	DNA mismatch repair protein MSH1, mitochondrial	15611870	Analysis of the functional domains of the mismatch repair homologue Msh1p and its role in mitochondrial genome maintenance.

O95336	6PGL_HUMAN	6-phosphogluconolactonase	10518023	Identification of the cDNA encoding human 6-phosphogluconolactonase, the enzyme catalyzing the second step of the pentose phosphate pathway.

P37268	FDFT_HUMAN	Squalene synthase	10896663	Crystal structure of human squalene synthase. A key enzyme in cholesterol biosynthesis.

Q9D198	SYF2_MOUSE	Pre-mRNA-splicing factor SYF2	12437976	Cloning, expression, and genomic organization of mouse mp29 gene.

P92980	APR3_ARATH	5'-adenylylsulfate reductase 3, chloroplastic	8917600	Sulfate reduction in higher plants: molecular evidence for a novel 5'-adenylylsulfate reductase.

Q9SNB9	TRP2_ARATH	Telomere repeat-binding protein 2	15688221	AtTBP2 and AtTRP2 in Arabidopsis encode proteins that bind plant telomeric DNA and induce DNA bending in vitro.

Q12354	APTH1_YEAST	Acyl-protein thioesterase 1	12080046	Characterization of Saccharomyces cerevisiae acyl-protein thioesterase 1, the enzyme responsible for G protein alpha subunit deacylation in vivo.

Q12906	ILF3_HUMAN	Interleukin enhancer-binding factor 3	11739746	The RNA binding protein nuclear factor 90 functions as both a positive and negative regulator of gene expression in mammalian cells.

Q9NVI1	FANCI_HUMAN	Fanconi anemia group I protein	17460694	FANCI is a second monoubiquitinated member of the Fanconi anemia pathway.

P49775	HNT2_YEAST	Bis(5'-adenosyl)-triphosphatase	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Q96PD4	IL17F_HUMAN	Interleukin-17F	11591732	IL-17F, a novel cytokine selectively expressed in activated T cells and monocytes, regulates angiogenesis and endothelial cell cytokine production.

Q15554	TERF2_HUMAN	Telomeric repeat-binding factor 2	15383534	Telosome, a mammalian telomere-associated complex formed by multiple telomeric proteins.

O18756	GLCE_BOVIN	D-glucuronyl C5-epimerase	9346972	Biosynthesis of heparin/heparan sulfate. cDNA cloning and expression of D-glucuronyl C5-epimerase from bovine lung.

Q99457	NP1L3_HUMAN	Nucleosome assembly protein 1-like 3	8976385	Cloning, expression pattern and mapping to Xq of NAP1L3, a gene encoding a peptide homologous to human and yeast nucleosome assembly proteins.

O08970	TUFT1_MOUSE	Tuftelin	10806191	A tuftelin-interacting protein (TIP39) localizes to the apical secretory pole of mouse ameloblasts.

Q570C0	TIR1_ARATH	Protein TRANSPORT INHIBITOR RESPONSE 1	15992545	Plant development is regulated by a family of auxin receptor F box proteins.

P31316	GSX2_MOUSE	GS homeobox 2	7619729	Gsh-2, a murine homeobox gene expressed in the developing brain.

P19334	TRP_DROME	Transient receptor potential protein	2516726	Molecular characterization of the Drosophila trp locus: a putative integral membrane protein required for phototransduction.

Q02821	IMA1_YEAST	Importin subunit alpha	16929305	Karyopherin-mediated import of integral inner nuclear membrane proteins.

Q9XT74	NRAM1_CANFA	Natural resistance-associated macrophage protein 1	12010961	Mapping and sequencing of the canine NRAMP1 gene and identification of mutations in leishmaniasis-susceptible dogs.

Q9C040	TRIM2_HUMAN	Tripartite motif-containing protein 2	11331580	The tripartite motif family identifies cell compartments.

Q8LAL2	IAA26_ARATH	Auxin-responsive protein IAA26	12036262	Genetics of Aux/IAA and ARF action in plant growth and development.

Q9CAC1	GUN8_ARATH	Endoglucanase 8	12602880	Abnormal 'wrinkled' cell walls and retarded development of transgenic Arabidopsis thaliana plants expressing endo-1,4-beta-glucanase (cell) antisense.

Q96CB8	INT12_HUMAN	Integrator complex subunit 12	16239144	Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.

P14003	HAIR_DROME	Protein hairy	14871887	Drosophila Topors is a RING finger-containing protein that functions as a ubiquitin-protein isopeptide ligase for the hairy basic helix- loop-helix repressor protein.

Q9UIK5	TEFF2_HUMAN	Tomoregulin-2	10987305	The gene for a novel transmembrane protein containing epidermal growth factor and follistatin domains is frequently hypermethylated in human tumor cells.

Q99633	PRP18_HUMAN	Pre-mRNA-splicing factor 18	9000057	A human protein required for the second step of pre-mRNA splicing is functionally related to a yeast splicing factor.

P27882	ERV1_YEAST	Mitochondrial FAD-linked sulfhydryl oxidase ERV1	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P43605	ECO1_YEAST	N-acetyltransferase ECO1	9990856	Yeast cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication.

Q6H9K0	PGLR2_PLAAC	Exopolygalacturonase	15208603	Identification of a polygalacturonase as a major allergen (Pla a 2) from Platanus acerifolia pollen.

Q9UKZ1	CB029_HUMAN	UPF0760 protein C2orf29	10497265	Identification of differentially expressed genes associated with HER- 2/neu overexpression in human breast cancer cells.

P01129	CDC10_SCHPO	Start control protein cdc10	8532516	Positive and negative roles for cdc10 in cell cycle gene expression.

P56696	KCNQ4_HUMAN	Potassium voltage-gated channel subfamily KQT member 4	10025409	KCNQ4, a novel potassium channel expressed in sensory outer hair cells, is mutated in dominant deafness.

P40035	PIC2_YEAST	Mitochondrial phosphate carrier protein 2	14756774	Redundancy in the function of mitochondrial phosphate transport in Saccharomyces cerevisiae and Arabidopsis thaliana.

P28698	MZF1_HUMAN	Myeloid zinc finger 1	1860835	A retinoic acid-responsive human zinc finger gene, MZF-1, preferentially expressed in myeloid cells.

Q9STX3	GID2_ARATH	F-box protein GID2	15161962	The Arabidopsis mutant sleepy1gar2-1 protein promotes plant growth by increasing the affinity of the SCFSLY1 E3 ubiquitin ligase for DELLA protein substrates.

P38200	SHE1_YEAST	Mitotic spindle-associated protein SHE1	17634282	A protein interaction map of the mitotic spindle.

Q8BX51	SGCZ_MOUSE	Zeta-sarcoglycan	12189167	Zeta-sarcoglycan, a novel component of the sarcoglycan complex, is reduced in muscular dystrophy.

Q64259	VHL_RAT	Von Hippel-Lindau disease tumor suppressor	7604013	Characterization of the VHL tumor suppressor gene product: localization, complex formation, and the effect of natural inactivating mutations.

P19012	K1C15_HUMAN	Keratin, type I cytoskeletal 15	2452170	Molecular characterization and expression of the stratification- related cytokeratins 4 and 15.

P58681	TLR7_MOUSE	Toll-like receptor 7	17452530	The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling.

P34788	RS18_ARATH	40S ribosomal protein S18	7913892	An S18 ribosomal protein gene copy at the Arabidopsis PFL locus affects plant development by its specific expression in meristems.

Q99287	SEY1_YEAST	Protein SEY1	19665976	A class of dynamin-like GTPases involved in the generation of the tubular ER network.

P28573	SC6A7_RAT	Sodium-dependent proline transporter	1350201	Molecular cloning and expression of a high affinity L-proline transporter expressed in putative glutamatergic pathways of rat brain.

P07099	HYEP_HUMAN	Epoxide hydrolase 1	7516776	Human microsomal epoxide hydrolase: genetic polymorphism and functional expression in vitro of amino acid variants.

P38694	MSC7_YEAST	Putative aldehyde dehydrogenase-like protein YHR039C	14562095	Global analysis of protein localization in budding yeast.

Q9XF11	U496D_ARATH	UPF0496 protein At3g28290/At3g28300	10196471	Isolation and characterization of a cDNA clone from Arabidopsis thaliana with partial sequence similarity to integrins.

O48686	SNL3_ARATH	Paired amphipathic helix protein Sin3-like 3	15994908	Role of an Arabidopsis AP2/EREBP-type transcriptional repressor in abscisic acid and drought stress responses.

P39177	USPG_ECOLI	Universal stress protein G	12071968	Identification and characterization of the Escherichia coli stress protein UP12, a putative in vivo substrate of GroEL.

Q86S05	LIG_DROME	Protein lingerer	14668197	Expression analysis of the lingerer gene in the larval central nervous system of Drosophila melanogaster.

P40477	NU159_YEAST	Nucleoporin NUP159	11739405	Ultrastructural localization of rRNA shows defective nuclear export of preribosomes in mutants of the Nup82p complex.

P17955	NUP62_RAT	Nuclear pore glycoprotein p62	8707840	Molecular and functional characterization of the p62 complex, an assembly of nuclear pore complex glycoproteins.

O94411	MFR2_SCHPO	Meiotic fizzy-related protein 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P04256	ROA1_RAT	Heterogeneous nuclear ribonucleoprotein A1	3005291	Structure of rodent helix-destabilizing protein revealed by cDNA cloning.

P46062	SIPA1_MOUSE	Signal-induced proliferation-associated protein 1	7799964	Molecular cloning of a novel mitogen-inducible nuclear protein with a Ran GTPase-activating domain that affects cell cycle progression.

Q9STX5	ENPL_ARATH	Endoplasmin homolog	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q9USQ4	SIM3_SCHPO	NASP-related protein sim3	18158900	A NASP (N1/N2)-related protein, Sim3, binds CENP-A and is required for its deposition at fission yeast centromeres.

Q9W420	SPT6H_DROME	Transcription elongation factor SPT6	11040217	High-resolution localization of Drosophila Spt5 and Spt6 at heat shock genes in vivo: roles in promoter proximal pausing and transcription elongation.

Q9P3U1	YKX5_SCHPO	Uncharacterized RNA-binding protein C328.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P46677	TAF1_YEAST	Transcription initiation factor TFIID subunit 1	10788514	Identification of two novel TAF subunits of the yeast Saccharomyces cerevisiae TFIID complex.

Q15008	PSMD6_HUMAN	26S proteasome non-ATPase regulatory subunit 6	10723133	The p44S10 locus, encoding a subunit of the proteasome regulatory particle, is amplified during progression of cutaneous malignant melanoma.

P25323	MYLKA_DICDI	Myosin light chain kinase A	1651931	Characterization and bacterial expression of the Dictyostelium myosin light chain kinase cDNA. Identification of an autoinhibitory domain.

O75084	FZD7_HUMAN	Frizzled-7	9707618	A novel frizzled gene identified in human esophageal carcinoma mediates APC/beta-catenin signals.

Q9Y5J7	TIM9_HUMAN	Mitochondrial import inner membrane translocase subunit Tim9	10552927	The human family of deafness/dystonia peptide (DDP) related mitochondrial import proteins.

O43556	SGCE_HUMAN	Epsilon-sarcoglycan	9405466	Epsilon-sarcoglycan, a broadly expressed homologue of the gene mutated in limb-girdle muscular dystrophy 2D.

O94276	YORS_SCHPO	Meiotic chromosome segregation protein P8B7.28c	16169489	Novel genes required for meiotic chromosome segregation are identified by a high-throughput knockout screen in fission yeast.

Q7TMB8	CYFP1_MOUSE	Cytoplasmic FMR1-interacting protein 1	18805096	The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP.

P32874	HFA1_YEAST	Acetyl-CoA carboxylase, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P39428	TRAF1_MOUSE	TNF receptor-associated factor 1	8069916	A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor.

Q9LDA9	CAF2P_ARATH	CRS2-associated factor 2, chloroplastic	17071648	Arabidopsis orthologs of maize chloroplast splicing factors promote splicing of orthologous and species-specific group II introns.

O88350	RBBP9_RAT	Putative hydrolase RBBP9	9697699	A retinoblastoma-binding protein that affects cell-cycle control and confers transforming ability.

Q8CII8	SYNE4_MOUSE	Nesprin-4	19164528	Nesprin 4 is an outer nuclear membrane protein that can induce kinesin-mediated cell polarization.

Q9Y221	NIP7_HUMAN	60S ribosome subunit biogenesis protein NIP7 homolog	17643419	The Shwachman-Bodian-Diamond syndrome associated protein interacts with HsNip7 and its down-regulation affects gene expression at the transcriptional and translational levels.

Q9UI17	M2GD_HUMAN	Dimethylglycine dehydrogenase, mitochondrial	10102904	Defect in dimethylglycine dehydrogenase, a new inborn error of metabolism: NMR spectroscopy study.

P53064	RTF1_YEAST	RNA polymerase-associated protein RTF1	11884586	Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex.

Q91VA0	ACSM1_MOUSE	Acyl-coenzyme A synthetase ACSM1, mitochondrial	11470804	Molecular identification and characterization of two medium-chain acyl-CoA synthetases, MACS1 and the Sa gene product.

O74461	MU123_SCHPO	Meiotically up-regulated gene 123 protein	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

Q9V8W3	RABEP_DROME	Rab proteins geranylgeranyltransferase component A	10082978	Antibody identification, chromosome map assignment, and sequence analysis of a Rab escort protein homolog in Drosophila.

Q9GT50	MTH_DROYA	G-protein coupled receptor Mth	10995474	Adaptive evolution of a candidate gene for aging in Drosophila.

Q39243	TRXB1_ARATH	Thioredoxin reductase 1	11717467	Identification and characterization of a mitochondrial thioredoxin system in plants.

O49484	ASK11_ARATH	SKP1-like protein 11	14749489	Expression and interaction analysis of Arabidopsis Skp1-related genes.

P39019	RS19_HUMAN	40S ribosomal protein S19	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

P0C2B8	RM55_BOVIN	39S ribosomal protein L55, mitochondrial	11551941	The large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present.

Q9C107	MCL1_SCHPO	Minichromosome loss protein 1	12455694	mcl1+, the Schizosaccharomyces pombe homologue of CTF4, is important for chromosome replication, cohesion, and segregation.

Q38912	RAC3_ARATH	Rac-like GTP-binding protein ARAC3	11387211	Arabidopsis thaliana Rop GTPases are localized to tips of root hairs and control polar growth.

Q96G97	BSCL2_HUMAN	Seipin	14981520	Heterozygous missense mutations in BSCL2 are associated with distal hereditary motor neuropathy and Silver syndrome.

Q06681	YSP2_YEAST	GRAM domain-containing protein YSP2	16962064	Ysp2 mediates death of yeast induced by amiodarone or intracellular acidification.

Q9NS37	ZHANG_HUMAN	CREB/ATF bZIP transcription factor	15705566	Zhangfei is a potent and specific inhibitor of the host cell factor- binding transcription factor Luman.

O94672	SC232_SCHPO	Protein transport protein sec23-2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9SYQ8	CLV1_ARATH	Receptor protein kinase CLAVATA1	9160749	The CLAVATA1 gene encodes a putative receptor kinase that controls shoot and floral meristem size in Arabidopsis.

P84869	PVAP_PHAVU	Antifungal lectin PVAP	16026901	An antifungal protein from flageolet beans.

Q9VT50	INSL1_DROME	Probable insulin-like peptide 1	11250149	An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control.

Q12029	FSF1_YEAST	Probable mitochondrial transport protein FSF1	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

O15205	UBD_HUMAN	Ubiquitin D	12730673	Expression of the FAT10 gene is highly upregulated in hepatocellular carcinoma and other gastrointestinal and gynecological cancers.

Q9SEL6	VTI11_ARATH	Vesicle transport v-SNARE 11	10397763	The plant vesicle-associated SNARE AtVTI1a likely mediates vesicle transport from the trans-Golgi network to the prevacuolar compartment.

P31318	ARG56_SCHPO	Protein arg11, mitochondrial	1313366	Cloning and sequencing of arg3 and arg11 genes of Schizosaccharomyces pombe on a 10-kb DNA fragment. Heterologous expression and mitochondrial targeting of their translation products.

O14356	TOR1_SCHPO	Phosphatidylinositol 3-kinase tor1	11096119	The fission yeast TOR homolog, tor1+, is required for the response to starvation and other stresses via a conserved serine.

Q9P7H1	FLP1_SCHPO	Tyrosine-protein phosphatase CDC14 homolog	11683392	Flp1, a fission yeast orthologue of the s. cerevisiae CDC14 gene, is not required for cyclin degradation or rum1p stabilisation at the end of mitosis.

Q9UBP0	SPAST_HUMAN	Spastin	10610178	Spastin, a new AAA protein, is altered in the most frequent form of autosomal dominant spastic paraplegia.

O15457	MSH4_HUMAN	MutS protein homolog 4	9299235	Cloning and expression analysis of a meiosis-specific MutS homolog: the human MSH4 gene.

Q9NP71	WBS14_HUMAN	Williams-Beuren syndrome chromosomal region 14 protein	11230181	WBSCR14, a gene mapping to the Williams-Beuren syndrome deleted region, is a new member of the Mlx transcription factor network.

O75154	RFIP3_HUMAN	Rab11 family-interacting protein 3	11481332	Identification of a novel Rab11/25 binding domain present in eferin and rip proteins.

Q09898	SID2_SCHPO	Serine/threonine-protein kinase sid2	10769201	The S. pombe orthologue of the S. cerevisiae mob1 gene is essential and functions in signalling the onset of septum formation.

P05543	THBG_HUMAN	Thyroxine-binding globulin	3094014	Complete amino acid sequence of human thyroxine-binding globulin deduced from cloned DNA: close homology to the serine antiproteases.

Q07820	MCL1_HUMAN	Induced myeloid leukemia cell differentiation protein Mcl-1	10837489	MCL-1S, a splicing variant of the antiapoptotic BCL-2 family member MCL-1, encodes a proapoptotic protein possessing only the BH3 domain.

Q9Y827	YEX5_SCHPO	Uncharacterized protein C1A6.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8LGA1	CCD41_ARATH	Cyclin-D4-1	10420643	A new D-type cyclin of Arabidopsis thaliana expressed during lateral root primordia formation.

Q9WVH8	FBLN5_RAT	Fibulin-5	10347091	EVEC, a novel epidermal growth factor-like repeat-containing protein upregulated in embryonic and diseased adult vasculature.

P38927	REV7_YEAST	DNA polymerase zeta processivity subunit	8658138	Thymine-thymine dimer bypass by yeast DNA polymerase zeta.

Q8TFH2	YIKC_SCHPO	Uncharacterized mitochondrial carrier PB17E12.12c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O15247	CLIC2_HUMAN	Chloride intracellular channel protein 2	9339381	Genomic structure of a novel chloride channel gene, CLIC2, in Xq28.

Q5FBB7	SGOL1_HUMAN	Shugoshin-like 1	17617734	Shugoshin 1 plays a central role in kinetochore assembly and is required for kinetochore targeting of Plk1.

Q80VW5	WHRN_MOUSE	Whirlin	15590698	Myosin XVa and whirlin, two deafness gene products required for hair bundle growth, are located at the stereocilia tips and interact directly.

Q06277	IBPA_HAES2	Adenosine monophosphate-protein transferase and cysteine protease ibpA	19362538	The fic domain: regulation of cell signaling by adenylylation.

P52045	MMCD_ECOLI	Methylmalonyl-CoA decarboxylase	10769117	Discovering new enzymes and metabolic pathways: conversion of succinate to propionate by Escherichia coli.

Q08271	GAS4_YEAST	1,3-beta-glucanosyltransferase GAS4	10383953	Amino acid residues in the omega-minus region participate in cellular localization of yeast glycosylphosphatidylinositol-attached proteins.

Q86NH1	SYD1_CAEEL	Rho GTPase-activating protein syd-1	12379863	SYD-1, a presynaptic protein with PDZ, C2 and rhoGAP-like domains, specifies axon identity in C. elegans.

P19999	MBL1_RAT	Mannose-binding protein A	10913141	Interaction of mannose-binding protein with associated serine proteases: effects of naturally occuring mutations.

P32790	SLA1_YEAST	Actin cytoskeleton-regulatory complex protein SLA1	11940605	Sla1p serves as the targeting signal recognition factor for NPFX(1,2)D-mediated endocytosis.

Q642G2	SOSD1_RAT	Sclerostin domain-containing protein 1	12390898	Uterine sensitization-associated gene-1: a novel gene induced within the rat endometrium at the time of uterine receptivity/sensitization for the decidual cell reaction.

P47860	K6PP_RAT	6-phosphofructokinase type C	8106374	Structure, distribution, and functional expression of the phosphofructokinase C isozyme.

O04308	MPPA2_ARATH	Probable mitochondrial-processing peptidase subunit alpha-2	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q06393	CLCKA_RAT	Chloride channel protein ClC-Ka	7680033	Molecular cloning of a chloride channel that is regulated by dehydration and expressed predominantly in kidney medulla.

Q9D0M5	DYL2_MOUSE	Dynein light chain 2, cytoplasmic	14561217	Localization of dynein light chains 1 and 2 and their pro-apoptotic ligands.

Q10426	RIK1_SCHPO	Chromatin modification-related protein rik1	16024659	A Rik1-associated, cullin-dependent E3 ubiquitin ligase is essential for heterochromatin formation.

Q4VGL6	RC3H1_MOUSE	Roquin	15917799	A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity.

O95222	OR6A2_HUMAN	Olfactory receptor 6A2	9787077	Organization and evolution of olfactory receptor genes on human chromosome 11.

P46555	GLCE_CAEEL	D-glucuronyl C5-epimerase	15003172	Differential sulfations and epimerization define heparan sulfate specificity in nervous system development.

P47164	MET7_YEAST	Cystathionine gamma-synthase	10821189	Cysteine is essential for transcriptional regulation of the sulfur assimilation genes in Saccharomyces cerevisiae.

P25632	RSC6_YEAST	Chromatin structure-remodeling complex protein RSC6	10619019	Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains.

P58985	GR59D_DROME	Putative gustatory receptor 59d	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

P40540	EMC5_YEAST	ER membrane protein complex subunit 5	14562095	Global analysis of protein localization in budding yeast.

Q05790	CRR1_YEAST	Probable glycosidase CRR1	15470107	CRR1, a gene encoding a putative transglycosidase, is required for proper spore wall assembly in Saccharomyces cerevisiae.

P22515	UBA1_YEAST	Ubiquitin-activating enzyme E1 1	1989885	UBA 1: an essential yeast gene encoding ubiquitin-activating enzyme.

P15923	TFE2_HUMAN	Transcription factor E2-alpha	2493990	A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins.

O13652	SFI1_SCHPO	Protein sfi1	14504268	Sfi1p has conserved centrin-binding sites and an essential function in budding yeast spindle pole body duplication.

P25693	PCL2_YEAST	PHO85 cyclin-2	14688790	Late-G1 cyclin-CDK activity is essential for control of cell morphogenesis in budding yeast.

O15539	RGS5_HUMAN	Regulator of G-protein signaling 5	10471929	Genetic screens in yeast to identify mammalian nonreceptor modulators of G-protein signaling.

P0A9M2	HPRT_ECOLI	Hypoxanthine phosphoribosyltransferase	12070315	Crystal structures of free, IMP-, and GMP-bound Escherichia coli hypoxanthine phosphoribosyltransferase.

Q9Z262	CLD6_MOUSE	Claudin-6	10601346	Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins.

P00749	UROK_HUMAN	Urokinase-type plasminogen activator	6589620	Identification and primary sequence of an unspliced human urokinase poly(A)+ RNA.

Q9JJI6	PIGO_MOUSE	GPI ethanolamine phosphate transferase 3	10781593	Requirement of PIG-F and PIG-O for transferring phosphoethanolamine to the third mannose in glycosylphosphatidylinositol.

P23787	TERA_XENLA	Transitional endoplasmic reticulum ATPase	10682845	p97 ATPase, an ATPase involved in membrane fusion, interacts with DNA unwinding factor (DUF) that functions in DNA replication.

P53667	LIMK1_HUMAN	LIM domain kinase 1	18028908	The phosphorylation of p25/TPPP by LIM kinase 1 inhibits its ability to assemble microtubules.

Q61490	CD166_MOUSE	CD166 antigen	9209500	Characterization of mouse ALCAM (CD166): the CD6 binding domain is conserved in different homologs and mediates cross-species binding.

Q9D906	ATG7_MOUSE	Ubiquitin-like modifier-activating enzyme ATG7	12482611	Mouse Apg10 as an Apg12-conjugating enzyme: analysis by the conjugation-mediated yeast two-hybrid method.

Q9UQN3	CHM2B_HUMAN	Charged multivesicular body protein 2b	17928862	ESCRT-III recognition by VPS4 ATPases.

Q3UZD5	PRDM6_MOUSE	Putative histone-lysine N-methyltransferase PRDM6	16537907	PRISM/PRDM6, a transcriptional repressor that promotes the proliferative gene program in smooth muscle cells.

O60828	PQBP1_HUMAN	Polyglutamine-binding protein 1	9875212	Polar amino acid-rich sequences bind to polyglutamine tracts.

P42581	HMX3_MOUSE	Homeobox protein HMX3	15363417	Hmx2 and Hmx3 homeobox genes direct development of the murine inner ear and hypothalamus and can be functionally replaced by Drosophila Hmx.

P78363	ABCA4_HUMAN	Retinal-specific ATP-binding cassette transporter	9202155	The photoreceptor rim protein is an ABC transporter encoded by the gene for recessive Stargardt's disease (ABCR).

P53892	IBD2_YEAST	Protein IBD2	12072457	IBD2 encodes a novel component of the Bub2p-dependent spindle checkpoint in the budding yeast Saccharomyces cerevisiae.

P25613	ADY2_YEAST	Accumulation of dyads protein 2	17395151	Association of putative ammonium exporters Ato with detergent- resistant compartments of plasma membrane during yeast colony development: pH affects Ato1p localisation in patches.

Q9NVX0	HAUS2_HUMAN	HAUS augmin-like complex subunit 2	19369198	The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells.

Q9D6J1	LASS4_MOUSE	LAG1 longevity assurance homolog 4	12912983	Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors.

P82610	METE_CANAL	5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase	11681208	Analysis of the serologic response to systemic Candida albicans infection in a murine model.

Q8NFH3	NUP43_HUMAN	Nucleoporin Nup43	17363900	The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions.

Q14164	IKKE_HUMAN	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	16177806	Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus.

P58954	GR22F_DROME	Putative gustatory receptor 22f	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

Q9Y1J3	PDPK1_CAEEL	3-phosphoinositide-dependent protein kinase 1	15068796	C. elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span.

Q9BQA5	HINFP_HUMAN	Histone H4 transcription factor	14752047	Sequence-specific transcriptional repression by an MBD2-interacting zinc finger protein MIZF.

Q9JJP0	S20A1_RAT	Sodium-dependent phosphate transporter 1	9528951	Molecular cloning and hormonal regulation of PiT-1, a sodium- dependent phosphate cotransporter from rat parathyroid glands.

Q9CAI3	CADH1_ARATH	Probable cinnamyl alcohol dehydrogenase 1	17467016	Expression of cinnamyl alcohol dehydrogenases and their putative homologues during Arabidopsis thaliana growth and development: lessons for database annotations?

Q9NPA1	KCMB3_HUMAN	Calcium-activated potassium channel subunit beta-3	10766764	Cloning and functional expression of two families of Beta-subunits of the large conductance calcium-activated potassium channel.

Q9FWR4	DHAR1_ARATH	Glutathione S-transferase DHAR1, mitochondrial	16262714	Coordinated activation of metabolic pathways for antioxidants and defence compounds by jasmonates and their roles in stress tolerance in Arabidopsis.

Q9L4Q7	PROX_CLOST	Prolyl-tRNA editing protein proX	14663147	Trans-editing of mischarged tRNAs.

Q9UM63	PLAL1_HUMAN	Zinc finger protein PLAGL1	9671765	hZAC encodes a zinc finger protein with antiproliferative properties and maps to a chromosomal region frequently lost in cancer.

Q9LXN4	HIRA_ARATH	Protein HIRA	16243907	Maize rough sheath2 and its Arabidopsis orthologue ASYMMETRIC LEAVES1 interact with HIRA, a predicted histone chaperone, to maintain knox gene silencing and determinacy during organogenesis.

O75012	MRP10_YEAST	37S ribosomal protein MRP10, mitochondrial	9151978	Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae.

Q8WUM4	PDC6I_HUMAN	Programmed cell death 6-interacting protein	17350572	Structural and biochemical studies of ALIX/AIP1 and its role in retrovirus budding.

Q12098	SLX4_YEAST	Structure-specific endonuclease subunit SLX4	12832395	Slx1-Slx4 is a second structure-specific endonuclease functionally redundant with Sgs1-Top3.

Q86VS8	HOOK3_HUMAN	Protein Hook homolog 3	17237231	The microtubule-binding protein Hook3 interacts with a cytoplasmic domain of scavenger receptor A.

Q90WY6	ADA2C_DANRE	Alpha-2C adrenergic receptor	15655522	Conserved structural, pharmacological and functional properties among the three human and five zebrafish alpha2-adrenoceptors.

Q99728	BARD1_HUMAN	BRCA1-associated RING domain protein 1	14976165	BRCA1:BARD1 induces the formation of conjugated ubiquitin structures, dependent on K6 of ubiquitin, in cells during DNA replication and repair.

Q6P2C8	MED27_HUMAN	Mediator of RNA polymerase II transcription subunit 27	9989412	The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1.

P62136	PP1A_HUMAN	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit	19377461	GlcNAcylation of a histone methyltransferase in retinoic-acid-induced granulopoiesis.

Q9UNY4	TTF2_HUMAN	Transcription termination factor 2	9748214	A human RNA polymerase II transcription termination factor is a SWI2/SNF2 family member.

O75164	KDM4A_HUMAN	Lysine-specific demethylase 4A	16024779	JMJD2A is a novel N-CoR-interacting protein and is involved in repression of the human transcription factor achaete scute-like homologue 2 (ASCL2/Hash2).

Q9BZS1	FOXP3_HUMAN	Forkhead box protein P3	11138001	Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse.

Q6PAR5	GAPD1_MOUSE	GTPase-activating protein and VPS9 domain-containing protein 1	17189207	Gapex-5, a Rab31 guanine nucleotide exchange factor that regulates Glut4 trafficking in adipocytes.

Q9Y7J3	YOI7_SCHPO	UPF0586 protein C1778.07	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q90VV1	HES4B_XENLA	Transcription factor HES-4-B	14648848	Identification of BOIP, a novel cDNA highly expressed during spermatogenesis that encodes a protein interacting with the orange domain of the hairy-related transcription factor HRT1/Hey1 in Xenopus and mouse.

Q63616	VP33B_RAT	Vacuolar protein sorting-associated protein 33B	8996080	Mammalian homologues of yeast vacuolar protein sorting (vps) genes implicated in Golgi-to-lysosome trafficking.

P21807	PERI_RAT	Peripherin	2624740	Structure of the gene encoding peripherin, an NGF-regulated neuronal- specific type III intermediate filament protein.

P32835	GSP1_YEAST	GTP-binding nuclear protein GSP1/CNR1	8455603	GSP1 and GSP2, genetic suppressors of the prp20-1 mutant in Saccharomyces cerevisiae: GTP-binding proteins involved in the maintenance of nuclear organization.

Q9UDW1	QCR9_HUMAN	Cytochrome b-c1 complex subunit 9	8592474	Ubiquinol-cytochrome-c reductase from human and bovine mitochondria.

Q09161	NCBP1_HUMAN	Nuclear cap-binding protein subunit 1	8069914	A nuclear cap binding protein complex involved in pre-mRNA splicing.

Q63046	RUNX1_RAT	Runt-related transcription factor 1	7969143	AML1 is expressed in skeletal muscle and is regulated by innervation.

P54385	DHE3_DROME	Glutamate dehydrogenase, mitochondrial	6810872	Purification and genetic control of NAD-dependent glutamate dehydrogenase from Drosophila melanogaster.

Q804A5	EPA2A_XENLA	Embryonic polyadenylate-binding protein 2-A	15380618	Identification of a novel Xenopus laevis poly(A) binding protein.

P29374	ARI4A_HUMAN	AT-rich interactive domain-containing protein 4A	8414517	Characterization of the retinoblastoma binding proteins RBP1 and RBP2.

P93654	SYP22_ARATH	Syntaxin-22	9305917	The AtVAM3 encodes a syntaxin-related molecule implicated in the vacuolar assembly in Arabidopsis thaliana.

Q92900	RENT1_HUMAN	Regulator of nonsense transcripts 1	16086026	Regulated degradation of replication-dependent histone mRNAs requires both ATR and Upf1.

Q9BZ95	NSD3_HUMAN	Histone-lysine N-methyltransferase NSD3	16682010	Characterization of a novel WHSC1-associated SET domain protein with H3K4 and H3K27 methyltransferase activity.

Q13651	I10R1_HUMAN	Interleukin-10 receptor subunit alpha	11485736	Crystal structure of the IL-10/IL-10R1 complex reveals a shared receptor binding site.

A4LBC0	LFL1_ORYSJ	B3 domain-containing protein LFL1	17913295	Overexpression of transcription factor OsLFL1 delays flowering time in Oryza sativa.

P87243	YC0I_SCHPO	Uncharacterized protein C4G3.18	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q93ZB2	KO1_ARATH	Ent-kaurene oxidase, chloroplastic	11722763	A plastid envelope location of Arabidopsis ent-kaurene oxidase links the plastid and endoplasmic reticulum steps of the gibberellin biosynthesis pathway.

P91793	DEFA_AEDAE	Defensin-A	7568275	Full sequence and characterization of two insect defensins: immune peptides from the mosquito Aedes aegypti.

Q06001	FAR10_YEAST	Factor arrest protein 10	12514182	Bipartite signals mediate subcellular targeting of tail-anchored membrane proteins in Saccharomyces cerevisiae.

Q94AH6	CUL1_ARATH	Cullin-1	18835996	F-box protein DOR functions as a novel inhibitory factor for abscisic acid-induced stomatal closure under drought stress in Arabidopsis.

Q94CD1	HHT1_ARATH	Omega-hydroxypalmitate O-feruloyl transferase	19759341	Identification of an Arabidopsis feruloyl-coenzyme A transferase required for suberin synthesis.

P93655	LONM1_ARATH	Lon protease homolog 1, mitochondrial	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

P32211	ACM4_MOUSE	Muscarinic acetylcholine receptor M4	7916637	Isolation, sequence and functional expression of the mouse m4 muscarinic acetylcholine receptor gene.

Q9NZR2	LRP1B_HUMAN	Low-density lipoprotein receptor-related protein 1B	10766186	LRP-DIT, a putative endocytic receptor gene, is frequently inactivated in non-small cell lung cancer cell lines.

Q09728	CUF1_SCHPO	Metal-binding regulatory protein cuf1	10593913	A copper-sensing transcription factor regulates iron uptake genes in Schizosaccharomyces pombe.

Q9NS86	LANC2_HUMAN	LanC-like protein 2	12566319	Lanthionine synthetase components C-like 2 increases cellular sensitivity to adriamycin by decreasing the expression of P- glycoprotein through a transcription-mediated mechanism.

Q86CS2	ATG1_DICDI	Serine/threonine-protein kinase atg1	15358773	Autophagy gene disruption reveals a non-vacuolar cell death pathway in Dictyostelium.

Q95KV7	NDUAD_BOVIN	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	11522775	GRIM-19, a cell death regulatory gene product, is a subunit of bovine mitochondrial NADH:ubiquinone oxidoreductase (complex I).

O94585	YQ7D_SCHPO	Meiotically up-regulated protein C1442.13c	16169489	Novel genes required for meiotic chromosome segregation are identified by a high-throughput knockout screen in fission yeast.

O00409	FOXN3_HUMAN	Forkhead box protein N3	9154802	Reconstitution of a MEC1-independent checkpoint in yeast by expression of a novel human fork head cDNA.

P61168	DRD2_MOUSE	D(2) dopamine receptor	1991517	Differential expression of the mouse D2 dopamine receptor isoforms.

P85110	SLAP2_BACHK	S-layer protein 2	16404726	Mass spectrometric sequencing of endotoxin proteins of Bacillus thuringiensis ssp. konkukian extracted from polyacrylamide gels.

P22794	EVI2A_HUMAN	Protein EVI2A	2117566	Identification and characterization of transcripts from the neurofibromatosis 1 region: the sequence and genomic structure of EVI2 and mapping of other transcripts.

Q5BPS0	LOG2_ARATH	Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG2	19837870	Functional analyses of LONELY GUY cytokinin-activating enzymes reveal the importance of the direct activation pathway in Arabidopsis.

P07834	CDC4_YEAST	Cell division control protein 4	9499404	Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box protein complexes that regulate cell division and methionine biosynthesis in yeast.

Q96SE0	ABHD1_HUMAN	Abhydrolase domain-containing protein 1	12735795	The gene structure and expression of human ABHD1: overlapping polyadenylation signal sequence with Sec12.

Q9VDW3	DMDB_DROME	Dystrophin, isoform B	16399704	Dystrophin is required for appropriate retrograde control of neurotransmitter release at the Drosophila neuromuscular junction.

Q9ERR8	ZN319_MOUSE	Zinc finger protein 319	11161788	Overexpression of a novel zinc-finger protein induces apoptosis in NIH3T3 fibroblasts.

P21579	SYT1_HUMAN	Synaptotagmin-1	19234194	Human SCAMP5, a novel secretory carrier membrane protein, facilitates calcium-triggered cytokine secretion by interaction with SNARE machinery.

O22241	AROD4_ARATH	Arogenate dehydratase 4, chloroplastic	17726025	Phenylalanine biosynthesis in Arabidopsis thaliana. Identification and characterization of arogenate dehydratases.

Q9H814	PHAX_HUMAN	Phosphorylated adapter RNA export protein	11333016	The evolutionarily conserved region of the U snRNA export mediator PHAX is a novel RNA-binding domain that is essential for U snRNA export.

P19484	TFEB_HUMAN	Transcription factor EB	19556463	A gene network regulating lysosomal biogenesis and function.

O75005	SYV_SCHPO	Valyl-tRNA synthetase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O75601	CASPD_BOVIN	Caspase-13	9624166	ERICE, a novel FLICE-activatable caspase.

P62993	GRB2_HUMAN	Growth factor receptor-bound protein 2	19914172	KIF26A is an unconventional kinesin and regulates GDNF-Ret signaling in enteric neuronal development.

Q8R2Z3	S26A7_MOUSE	Anion exchange transporter	15591059	SLC26A7 is a Cl- channel regulated by intracellular pH.

P47979	ZFS1_SCHPO	Zinc finger protein zfs1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P0CG37	CFC1_HUMAN	Cryptic protein	11062482	Loss-of-function mutations in the EGF-CFC gene CFC1 are associated with human left-right laterality defects.

Q8NBT2	SPC24_HUMAN	Kinetochore protein Spc24	15961401	Architecture of the human Ndc80-Hec1 complex, a critical constituent of the outer kinetochore.

Q7M370	AAAD_RABIT	Arylacetamide deacetylase	10318829	Targeting proteins to the lumen of endoplasmic reticulum using N- terminal domains of 11beta-hydroxysteroid dehydrogenase and the 50-kDa esterase.

P25932	ESCA_DROME	Protein escargot	8375329	Control of imaginal cell development by the escargot gene of Drosophila.

O94493	YC7C_SCHPO	Uncharacterized esterase/lipase C417.12	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UJX3	APC7_HUMAN	Anaphase-promoting complex subunit 7	16364912	Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C.

O08747	UNC5C_MOUSE	Netrin receptor UNC5C	9389662	Embryonic phenotype of Unc5h3 mutant mice suggests chemorepulsion during the formation of the rostral cerebellar boundary.

Q92905	CSN5_HUMAN	COP9 signalosome complex subunit 5	12082530	Interaction and colocalization of PGP9.5 with JAB1 and p27(Kip1).

Q9S1E4	NRFI_WOLSU	Protein nrfI	10672190	A NapC/NirT-type cytochrome c (NrfH) is the mediator between the quinone pool and the cytochrome c nitrite reductase of Wolinella succinogenes.

Q15121	PEA15_HUMAN	Astrocytic phosphoprotein PEA-15	8662970	The major astrocytic phosphoprotein PEA-15 is encoded by two mRNAs conserved on their full length in mouse and human.

P0A6K3	DEF_ECOLI	Peptide deformylase	7896716	Enzymatic properties of Escherichia coli peptide deformylase.

Q99MQ4	ASPN_MOUSE	Asporin	17522060	PLAP-1/asporin, a novel negative regulator of periodontal ligament mineralization.

Q99MG9	KCIP4_RAT	Kv channel-interacting protein 4	15356203	KChIPs and Kv4 alpha subunits as integral components of A-type potassium channels in mammalian brain.

P20814	CP2CD_RAT	Cytochrome P450 2C13, male-specific	2325668	Structural and regulatory analysis of the male-specific rat liver cytochrome P-450 g: repression by continuous growth hormone administration.

O94654	YGF3_SCHPO	Uncharacterized transporter C405.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q80UM3	NAA15_MOUSE	N-alpha-acetyltransferase 15, NatA auxiliary subunit	10842358	Tubedown-1, a novel acetyltransferase associated with blood vessel development.

Q03180	PIR3_YEAST	Cell wall mannoprotein PIR3	15781460	Comprehensive proteomic analysis of Saccharomyces cerevisiae cell walls: identification of proteins covalently attached via glycosylphosphatidylinositol remnants or mild alkali-sensitive linkages.

Q9Y6Q6	TNR11_HUMAN	Tumor necrosis factor receptor superfamily member 11A	9367155	A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function.

Q0WLC6	PP349_ARATH	Pentatricopeptide repeat-containing protein At4g34830, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q8VDL9	GLIS2_MOUSE	Zinc finger protein GLIS2	11741991	Characterization of Glis2, a novel gene encoding a Gli-related, Kruppel-like transcription factor with transactivation and repressor functions. Roles in kidney development and neurogenesis.

Q8K1Q3	GPR3_RAT	G-protein coupled receptor 3	12220620	Sphingosine 1-phosphate is a ligand of the human gpr3, gpr6 and gpr12 family of constitutively active G protein-coupled receptors.

P45974	UBP5_HUMAN	Ubiquitin carboxyl-terminal hydrolase 5	19098288	Suppression of the deubiquitinating enzyme USP5 causes the accumulation of unanchored polyubiquitin and the activation of p53.

P49589	SYCC_HUMAN	Cysteinyl-tRNA synthetase, cytoplasmic	11347887	Isolation of two cDNAs encoding functional human cytoplasmic cysteinyl-tRNA synthetase.

Q9Y2X7	GIT1_HUMAN	ARF GTPase-activating protein GIT1	9826657	Beta2-adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein.

Q8VEB4	PAG15_MOUSE	Group XV phospholipase A2	11790796	Cloning and characterization of a lysosomal phospholipase A2, 1-O- acylceramide synthase.

Q9Z1J3	NFS1_MOUSE	Cysteine desulfurase, mitochondrial	9738949	cDNA cloning and characterization of mouse nifS-like protein, m-Nfs1: mitochondrial localization of eukaryotic NifS-like proteins.

P29952	MPI_YEAST	Mannose-6-phosphate isomerase	1377774	PMI40, an intron-containing gene required for early steps in yeast mannosylation.

Q03834	MSH6_YEAST	DNA mismatch repair protein MSH6	16702432	Analysis of the proteins involved in the in vivo repair of base-base mismatches and four-base loops formed during meiotic recombination in the yeast Saccharomyces cerevisiae.

P68163	FER_DATIN	Ferredoxin	7764481	Identical amino acid sequence of ferredoxin from Datura metel and D. innoxia.

Q9UHG2	PCSK1_HUMAN	ProSAAS	10632593	Identification and characterization of proSAAS, a granin-like neuroendocrine peptide precursor that inhibits prohormone processing.

Q9UW19	MTAL1_CANAL	Mating-type-like protein ALPHA1	14622594	Evolution of a combinatorial transcriptional circuit: a case study in yeasts.

Q9P3W5	TEL2_SCHPO	DNA replication checkpoint protein tel2	17189249	Tel2 is required for activation of the Mrc1-mediated replication checkpoint.

Q7TSA3	BTLA_MOUSE	B- and T-lymphocyte attenuator	15568026	B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator.

Q9RYE6	DDRC_DEIRA	DNA damage response protein C	15454524	Analysis of Deinococcus radiodurans's transcriptional response to ionizing radiation and desiccation reveals novel proteins that contribute to extreme radioresistance.

Q7TN49	MRGRA_RAT	Mas-related G-protein coupled receptor member A	12909716	Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family.

Q9EP95	RETNA_MOUSE	Resistin-like alpha	11209052	A family of tissue-specific resistin-like molecules.

P40563	AIM21_YEAST	Altered inheritance of mitochondria protein 21	14562095	Global analysis of protein localization in budding yeast.

P15291	B4GT1_HUMAN	Beta-1,4-galactosyltransferase 1	7744867	Golgi retention mechanism of beta-1,4-galactosyltransferase. Membrane-spanning domain-dependent homodimerization and association with alpha- and beta-tubulins.

P82858	URIC_PUCRE	Uricase	11910495	Urate oxidase from the rust Puccinia recondita is a heterotetramer with two different-sized monomers.

Q99547	MPH6_HUMAN	M-phase phosphoprotein 6	15231747	A protein interaction framework for human mRNA degradation.

P41743	KPCI_HUMAN	Protein kinase C iota type	15590654	Structure of a cell polarity regulator, a complex between atypical PKC and Par6 PB1 domains.

O15372	EIF3H_HUMAN	Eukaryotic translation initiation factor 3 subunit H	18599441	Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3.

Q9NZC7	WWOX_HUMAN	WW domain-containing oxidoreductase	19465938	Inhibition of the Wnt/beta-catenin pathway by the WWOX tumor suppressor protein.

P34537	BRE1_CAEEL	E3 ubiquitin-protein ligase bre-1	14732404	Characterization of C. elegans RING finger protein 1, a binding partner of ubiquitin-conjugating enzyme 1.

Q9UBF1	MAGC2_HUMAN	Melanoma-associated antigen C2	12920247	HCA587 antigen expression in normal tissues and cancers: correlation with tumor differentiation in hepatocellular carcinoma.

P20436	RPAB3_YEAST	DNA-directed RNA polymerases I, II, and III subunit RPABC3	2186966	Subunits shared by eukaryotic nuclear RNA polymerases.

P34122	CAP2_DICDI	cAMP-binding protein 2	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

Q9LX66	HERK_ARATH	Receptor-like protein kinase HERK 1	17644812	A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome.

P31377	STX8_YEAST	Syntaxin-8	12453154	A new yeast endosomal SNARE related to mammalian syntaxin 8.

P38971	ALP1_YEAST	Basic amino-acid permease	10654085	Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae.

Q00711	DHSA_YEAST	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	19628817	SDH5, a gene required for flavination of succinate dehydrogenase, is mutated in paraganglioma.

P46935	NEDD4_MOUSE	E3 ubiquitin-protein ligase NEDD4	15060076	Grb10 prevents Nedd4-mediated vascular endothelial growth factor receptor-2 degradation.

P06319	LV605_HUMAN	Ig lambda chain V-VI region EB4	3923440	Cloning and sequence analysis of an Ig lambda light chain mRNA expressed in the Burkitt's lymphoma cell line EB4.

Q9NHC3	CED2_CAEEL	Cell death abnormality protein 2	15744306	Two pathways converge at CED-10 to mediate actin rearrangement and corpse removal in C. elegans.

O74352	HOB1_SCHPO	Protein hob1	12569356	hob1+, the fission yeast homolog of Bin1, is dispensable for endocytosis or actin organization, but required for the response to starvation or genotoxic stress.

O33245	PSB_MYCTU	Proteasome subunit beta	19759536	Inhibitors selective for mycobacterial versus human proteasomes.

Q04712	RRN11_YEAST	RNA polymerase I-specific transcription initiation factor RRN11	8702872	RRN11 encodes the third subunit of the complex containing Rrn6p and Rrn7p that is essential for the initiation of rDNA transcription by yeast RNA polymerase I.

Q9LVG4	APRR3_ARATH	Two-component response regulator-like APRR3	11100772	Circadian waves of expression of the APRR1/TOC1 family of pseudo- response regulators in Arabidopsis thaliana: insight into the plant circadian clock.

P51839	GUC2D_RAT	Olfactory guanylyl cyclase GC-D	7724600	A receptor guanylyl cyclase expressed specifically in olfactory sensory neurons.

P49135	ERCC3_MOUSE	TFIIH basal transcription factor complex helicase XPB subunit	1747940	Characterization of the mouse homolog of the XPBC/ERCC-3 gene implicated in xeroderma pigmentosum and Cockayne's syndrome.

Q9ZPV8	COAD_ARATH	Phosphopantetheine adenylyltransferase	18621975	The coenzyme A biosynthetic enzyme phosphopantetheine adenylyltransferase plays a crucial role in plant growth, salt/osmotic stress resistance, and seed lipid storage.

Q9HCQ5	GALT9_HUMAN	Polypeptide N-acetylgalactosaminyltransferase 9	10978536	Brain-specific expression of a novel human UDP-GalNAc:polypeptide N- acetylgalactosaminyltransferase (GalNAc-T9).

B2ZGJ1	CLAT_DANRE	Choline O-acetyltransferase	18684905	Function of neuromuscular synapses in the zebrafish choline- acetyltransferase mutant bajan.

P41236	IPP2_HUMAN	Protein phosphatase inhibitor 2	9126490	Genetic analysis of human type 1 protein phosphatase inhibitor 2 in insulin-resistant Pima Indians.

Q9SRH5	VDAC1_ARATH	Mitochondrial outer membrane protein porin 1	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q09824	REP2_SCHPO	Transcriptional activator protein rep2	7588609	Fission yeast Rep2 is a putative transcriptional activator subunit for the cell cycle 'start' function of Res2-Cdc10.

O14965	STK6_HUMAN	Serine/threonine-protein kinase 6	18662907	Modulation of kinase-inhibitor interactions by auxiliary protein binding: crystallography studies on Aurora A interactions with VX-680 and with TPX2.

Q8BVL9	JKIP1_MOUSE	Janus kinase and microtubule-interacting protein 1	17532644	Marlin-1 and conventional kinesin link GABAB receptors to the cytoskeleton and regulate receptor transport.

P54789	ORC1_SCHPO	Origin recognition complex subunit 1	8618924	Orp1, a member of the Cdc18/Cdc6 family of S-phase regulators, is homologous to a component of the origin recognition complex.

P35368	ADA1B_HUMAN	Alpha-1B adrenergic receptor	1328250	Genomic organization and expression of the human alpha 1B-adrenergic receptor.

C0H4W3	HEPF1_PLAF7	Probable ATP-dependent helicase PF08_0048	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

Q9C0B1	FTO_HUMAN	Alpha-ketoglutarate-dependent dioxygenase FTO	20376003	Crystal structure of the FTO protein reveals basis for its substrate specificity.

P46273	PGK_CANAL	Phosphoglycerate kinase	9043109	3-phosphoglycerate kinase: a glycolytic enzyme protein present in the cell wall of Candida albicans.

Q9NPI6	DCP1A_HUMAN	mRNA-decapping enzyme 1A	19150429	Human proline-rich nuclear receptor coregulatory protein 2 mediates an interaction between mRNA surveillance machinery and decapping complex.

P38241	SLT11_YEAST	Pre-mRNA-splicing factor SLT11	9528778	Synthetic lethality of yeast slt mutations with U2 small nuclear RNA mutations suggests functional interactions between U2 and U5 snRNPs that are important for both steps of pre-mRNA splicing.

P48023	TNFL6_HUMAN	Tumor necrosis factor ligand superfamily member 6	7826947	Human Fas ligand: gene structure, chromosomal location and species specificity.

Q14566	MCM6_HUMAN	DNA replication licensing factor MCM6	9286856	HsMCM6: a new member of the human MCM/P1 family encodes a protein homologous to fission yeast Mis5.

O13351	PMT3_SCHPO	Ubiquitin-like protein pmt3/smt3	10567589	Characterization of a fission yeast SUMO-1 homologue, pmt3p, required for multiple nuclear events, including the control of telomere length and chromosome segregation.

P20292	AL5AP_HUMAN	Arachidonate 5-lipoxygenase-activating protein	8440384	5-lipoxygenase-activating protein is an arachidonate binding protein.

Q9GRF8	EF1B_DICDI	Elongation factor 1-beta	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q64620	PPP6_RAT	Serine/threonine-protein phosphatase 6 catalytic subunit	8077208	Molecular cloning of a protein serine/threonine phosphatase containing a putative regulatory tetratricopeptide repeat domain.

Q9USU9	TOA1_SCHPO	Transcription initiation factor IIA large subunit	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q92900	RENT1_HUMAN	Regulator of nonsense transcripts 1	8855285	Mammalian orthologues of a yeast regulator of nonsense transcript stability.

Q9FJK3	AGL80_ARATH	Agamous-like MADS-box protein AGL80	16798889	AGL80 is required for central cell and endosperm development in Arabidopsis.

O95163	ELP1_HUMAN	Elongator complex protein 1	11714725	Purification and characterization of the human elongator complex.

Q9JI38	PUS3_MOUSE	tRNA pseudouridine synthase 3	11027153	Pseudouridine synthase 3 from mouse modifies the anticodon loop of tRNA.

Q10951	BYR4_SCHPO	Protein byr4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O74856	CAF1_SCHPO	Poly(A) ribonuclease pop2	17452359	The 1.4-A crystal structure of the S. pombe Pop2p deadenylase subunit unveils the configuration of an active enzyme.

P10415	BCL2_HUMAN	Apoptosis regulator Bcl-2	12901880	BNIPL-2, a novel homologue of BNIP-2, interacts with Bcl-2 and Cdc42GAP in apoptosis.

P01779	HV318_HUMAN	Ig heavy chain V-III region TUR	4522793	Variable region sequences of five human immunoglobulin heavy chains of the VH3 subgroup: definitive identification of four heavy chain hypervariable regions.

O43920	NDUS5_HUMAN	NADH dehydrogenase [ubiquinone] iron-sulfur protein 5	10070614	The human NADH:ubiquinone oxidoreductase NDUFS5 (15 kDa) subunit: cDNA cloning, chromosomal localization, tissue distribution and the absence of mutations in isolated complex I-deficient patients.

P47818	CCC1_YEAST	Protein CCC1	7941738	Sequence, mapping and disruption of CCC1, a gene that cross- complements the Ca(2+)-sensitive phenotype of csg1 mutants.

Q04863	RELB_MOUSE	Transcription factor RelB	7845467	Expression of relB is required for the development of thymic medulla and dendritic cells.

Q8K1E3	DLK2_MOUSE	Protein delta homolog 2	17320102	The novel gene EGFL9/Dlk2, highly homologous to Dlk1, functions as a modulator of adipogenesis.

P11277	SPTB1_HUMAN	Spectrin beta chain, erythrocyte	2195026	Full-length sequence of the cDNA for human erythroid beta-spectrin.

Q8RMH6	AURA_CHLAA	Auracyanin-A	12589566	A thin-film electrochemical study of the 'blue' copper proteins, auracyanin A and auracyanin B, from the photosynthetic bacterium Chloroflexus aurantiacus: the reduction potential as a function of pH.

Q62108	DLG4_MOUSE	Disks large homolog 4	19243221	Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning.

P33085	SHAKB_DROME	Innexin shaking-B	8500183	Passover: a gene required for synaptic connectivity in the giant fiber system of Drosophila.

Q09697	RGA8_SCHPO	Rho-GTPase-activating protein 8	14506270	The novel Rho GTPase-activating protein family protein, Rga8, provides a potential link between Cdc42/p21-activated kinase and Rho signaling pathways in the fission yeast, Schizosaccharomyces pombe.

Q06333	YD357_YEAST	Uncharacterized protein YDR357C	14562095	Global analysis of protein localization in budding yeast.

P36630	CG22_SCHPO	G2/mitotic-specific cyclin cig2	8657126	Cig2, a B-type cyclin, promotes the onset of S in Schizosaccharomyces pombe.

P21675	TAF1_HUMAN	Transcription initiation factor TFIID subunit 1	9858607	Rb inhibits the intrinsic kinase activity of TATA-binding protein- associated factor TAFII250.

P76249	LEUE_ECOLI	Leucine efflux protein	16098526	The yeaS (leuE) gene of Escherichia coli encodes an exporter of leucine, and the Lrp protein regulates its expression.

O75367	H2AY_HUMAN	Core histone macro-H2A.1	9714746	Isolation of cDNA clones encoding human histone macroH2A1 subtypes.

Q95US5	BRE5_CAEEL	Beta-1,3-galactosyltransferase bre-5	12944392	Resistance to a bacterial toxin is mediated by removal of a conserved glycosylation pathway required for toxin-host interactions.

Q9Y4W6	AFG32_HUMAN	AFG3-like protein 2	10395799	Identification and characterization of AFG3L2, a novel paraplegin- related gene.

Q9JIM1	S29A1_MOUSE	Equilibrative nucleoside transporter 1	11085929	Molecular cloning and functional characterization of inhibitor- sensitive (mENT1) and inhibitor-resistant (mENT2) equilibrative nucleoside transporters from mouse brain.

Q9VWU1	PSH_DROME	Serine protease persephone	12098703	Activation of Drosophila Toll during fungal infection by a blood serine protease.

Q7Z6Z7	HUWE1_HUMAN	E3 ubiquitin-protein ligase HUWE1	15767685	Characterization of E3Histone, a novel testis ubiquitin protein ligase which ubiquitinates histones.

Q9LSX9	ASK9_ARATH	SKP1-like protein 9	19682297	An F-box gene, CPR30, functions as a negative regulator of the defense response in Arabidopsis.

Q9VD76	GR93A_DROME	Putative gustatory receptor 93a	10710312	Candidate taste receptors in Drosophila.

Q96KK3	KCNS1_HUMAN	Potassium voltage-gated channel subfamily S member 1	10484328	Electrically silent potassium channel subunits from human lens epithelium.

P25101	EDNRA_HUMAN	Endothelin-1 receptor	8611157	Alternative RNA splicing of the human endothelin-A receptor generates multiple transcripts.

Q8K2I3	FMO2_MOUSE	Dimethylaniline monooxygenase [N-oxide-forming] 2	11835629	Sequencing, expression, and characterization of cDNA expressed flavin-containing monooxygenase 2 from mouse.

P43628	KI2L3_HUMAN	Killer cell immunoglobulin-like receptor 2DL3	9059894	Polymorphism and domain variability of human killer cell inhibitory receptors.

Q75I93	BGL07_ORYSJ	Beta-glucosidase 7	14692878	Beta-glucosidase, exo-beta-glucanase and pyridoxine transglucosylase activities of rice BGlu1.

P34343	NU133_CAEEL	Nuclear pore complex protein 15	12937276	Caenorhabditis elegans nucleoporins Nup93 and Nup205 determine the limit of nuclear pore complex size exclusion in vivo.

P22466	GALA_HUMAN	Galanin	1722333	Isolation and primary structure of pituitary human galanin, a 30- residue nonamidated neuropeptide.

P34125	DGKA_DICDI	Diacylglycerol kinase A	16854454	Analysis of two diacylglycerol kinase activities in mixed micelles.

B0B9A0	CDUB1_CHLT2	Deubiquitinase and deneddylase Dub1	18503636	ChlaDub1 of Chlamydia trachomatis suppresses NF-kappaB activation and inhibits IkappaBalpha ubiquitination and degradation.

P53893	RIA1_YEAST	Ribosome assembly protein 1	11713675	Ria1p (Ynl163c), a protein similar to elongation factors 2, is involved in the biogenesis of the 60S subunit of the ribosome in Saccharomyces cerevisiae.

P21281	VATB2_HUMAN	V-type proton ATPase subunit B, brain isoform	2145275	An mRNA from human brain encodes an isoform of the B subunit of the vacuolar H(+)-ATPase.

Q96242	CP74A_ARATH	Allene oxide synthase, chloroplastic	16461379	Protein profiling of plastoglobules in chloroplasts and chromoplasts. A surprising site for differential accumulation of metabolic enzymes.

Q13243	SRSF5_HUMAN	Serine/arginine-rich splicing factor 5	7556075	Identification and characterization of three members of the human SR family of pre-mRNA splicing factors.

Q7L523	RRAGA_HUMAN	Ras-related GTP-binding protein A	11073942	Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B.

Q8MU95	BGBP_PLOIN	Beta-1,3-glucan-binding protein	12770576	cDNA cloning, purification, properties and function of a beta-1,3- glucan recognition protein from a pyralid moth, Plodia interpunctella.

B2GUV7	IF2P_RAT	Eukaryotic translation initiation factor 5B	8667030	Molecular cloning and characterization of annexin V-binding proteins with highly hydrophilic peptide structure.

O70299	MB211_MOUSE	Protein mab-21-like 1	12642482	Cell-autonomous involvement of Mab21l1 is essential for lens placode development.

Q04119	PPN1_YEAST	Endopolyphosphatase	11447286	The endopolyphosphatase gene: essential in Saccharomyces cerevisiae.

Q12247	FYV7_YEAST	rRNA-processing protein FYV7	12837249	A panoramic view of yeast noncoding RNA processing.

Q9U6B8	CRCM1_DROME	Calcium release-activated calcium channel protein 1	16645049	CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry.

D0VWV4	C560_PIG	Succinate dehydrogenase cytochrome b560 subunit, mitochondrial	15989954	Crystal structure of mitochondrial respiratory membrane protein complex II.

Q9JJY4	DDX20_MOUSE	Probable ATP-dependent RNA helicase DDX20	16153597	Transcriptional factor FOXL2 interacts with DP103 and induces apoptosis.

Q08959	YP206_YEAST	Probable glycerophosphodiester phosphodiesterase YPL206C	16172116	Glycerophosphocholine catabolism as a new route for choline formation for phosphatidylcholine synthesis by the Kennedy pathway.

P49435	APT1_YEAST	Adenine phosphoribosyltransferase 1	14562095	Global analysis of protein localization in budding yeast.

O60566	BUB1B_HUMAN	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta	17981135	Human Blinkin/AF15q14 is required for chromosome alignment and the mitotic checkpoint through direct interaction with Bub1 and BubR1.

Q96B42	TMM18_HUMAN	Transmembrane protein 18	18559506	Transmembrane protein 18 enhances the tropism of neural stem cells for glioma cells.

P21127	CD11B_HUMAN	Cell division protein kinase 11B	12501247	CDK11 complexes promote pre-mRNA splicing.

Q2TA68	OPA1_RAT	Dynamin-like 120 kDa protein, mitochondrial	15505078	OPA1, the disease gene for autosomal dominant optic atrophy, is specifically expressed in ganglion cells and intrinsic neurons of the retina.

Q08905	FRE3_YEAST	Ferric reductase transmembrane component 3	10341420	Regulated expression of the Saccharomyces cerevisiae Fre1p/Fre2p Fe/Cu reductase related genes.

P28659	CELF1_MOUSE	CUGBP Elav-like family member 1	11158314	The CELF family of RNA binding proteins is implicated in cell- specific and developmentally regulated alternative splicing.

Q9FKH1	SAP_ARATH	Transcriptional regulator STERILE APETALA	10215627	Arabidopsis STERILE APETALA, a multifunctional gene regulating inflorescence, flower, and ovule development.

Q08220	GSHB_YEAST	Glutathione synthetase	12467574	Large conformational changes in the catalytic cycle of glutathione synthase.

O75173	ATS4_HUMAN	A disintegrin and metalloproteinase with thrombospondin motifs 4	10356395	Purification and cloning of aggrecanase-1: a member of the ADAMTS family of proteins.

Q08692	OSW1_YEAST	Outer spore wall protein 1	15590821	Morphogenetic pathway of spore wall assembly in Saccharomyces cerevisiae.

Q13838	UAP56_HUMAN	Spliceosome RNA helicase BAT1	18974867	Recruitment of the complete hTREX complex is required for Kaposi's sarcoma-associated herpesvirus intronless mRNA nuclear export and virus replication.

Q08550	MPC54_YEAST	Meiotic plaque component protein 54	10899120	Role of the spindle pole body of yeast in mediating assembly of the prospore membrane during meiosis.

P01019	ANGT_HUMAN	Angiotensinogen	16116425	Mutations in genes in the renin-angiotensin system are associated with autosomal recessive renal tubular dysgenesis.

Q2TBC4	PRIC4_HUMAN	Prickle-like protein 4	15702247	Characterization of OEBT, a LIM protein.

Q80WM3	CPLX4_MOUSE	Complexin-4	15911881	Structurally and functionally unique complexins at retinal ribbon synapses.

P48595	SPB10_HUMAN	Serpin B10	7592909	Molecular cloning of bomapin (protease inhibitor 10), a novel human serpin that is expressed specifically in the bone marrow.

P23284	PPIB_HUMAN	Peptidyl-prolyl cis-trans isomerase B	1530944	S-cyclophilin is retained intracellularly via a unique COOH-terminal sequence and colocalizes with the calcium storage protein calreticulin.

O95619	YETS4_HUMAN	YEATS domain-containing protein 4	10913114	GAS41, a highly conserved protein in eukaryotic nuclei, binds to NuMA.

Q16627	CCL14_HUMAN	C-C motif chemokine 14	8551235	HCC-1, a novel chemokine from human plasma.

O00574	CXCR6_HUMAN	C-X-C chemokine receptor type 6	9230441	Expression cloning of new receptors used by simian and human immunodeficiency viruses.

Q9QYY9	ADH4_MOUSE	Alcohol dehydrogenase 4	10514444	A novel subtype of class II alcohol dehydrogenase in rodents. Unique Pro(47) and Ser(182) modulates hydride transfer in the mouse enzyme.

P16435	NCPR_HUMAN	NADPH--cytochrome P450 reductase	2513880	Structural and functional analysis of NADPH-cytochrome P-450 reductase from human liver: complete sequence of human enzyme and NADPH-binding sites.

O94680	PDAT_SCHPO	Phospholipid:diacylglycerol acyltransferase	12963726	Schizosaccharomyces pombe cells deficient in triacylglycerols synthesis undergo apoptosis upon entry into the stationary phase.

Q15436	SC23A_HUMAN	Protein transport protein Sec23A	8898360	Cloning and functional characterization of mammalian homologues of the COPII component Sec23.

O81210	RBOHC_ARATH	Respiratory burst oxidase homolog protein C	12660786	Reactive oxygen species produced by NADPH oxidase regulate plant cell growth.

Q06432	CCG1_HUMAN	Voltage-dependent calcium channel gamma-1 subunit	8387489	Molecular characterization of the gene encoding the gamma subunit of the human skeletal muscle 1,4-dihydropyridine-sensitive Ca2+ channel (CACNLG), cDNA sequence, gene structure, and chromosomal location.

Q08886	GPB1_YEAST	Guanine nucleotide-binding protein subunit beta 1	16278446	Cyclic AMP-independent regulation of protein kinase A substrate phosphorylation by Kelch repeat proteins.

Q64617	KPCL_RAT	Protein kinase C eta type	1426252	Biochemical properties of rat protein kinase C-eta expressed in COS cells.

Q9S841	PSBO2_ARATH	Oxygen-evolving enhancer protein 1-2, chloroplastic	17217465	The Arabidopsis PsbO2 protein regulates dephosphorylation and turnover of the photosystem II reaction centre D1 protein.

P14373	TRI27_HUMAN	Zinc finger protein RFP	9570750	Ret finger protein is a normal component of PML nuclear bodies and interacts directly with PML.

O96612	UBPB_DICDI	Ubiquitin hydrolase B	9832508	A novel, putative MEK kinase controls developmental timing and spatial patterning in Dictyostelium and is regulated by ubiquitin- mediated protein degradation.

O00217	NDUS8_HUMAN	NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial	9837812	The first nuclear-encoded complex I mutation in a patient with Leigh syndrome.

P51746	IL10_CEREL	Interleukin-10	7579578	The cloning and sequencing of cervine interleukin 10.

Q08968	FMP40_YEAST	UPF0061 protein FMP40	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P15651	ACADS_RAT	Short-chain specific acyl-CoA dehydrogenase, mitochondrial	11812788	Crystal structure of rat short chain acyl-CoA dehydrogenase complexed with acetoacetyl-CoA: comparison with other acyl-CoA dehydrogenases.

Q16581	C3AR_HUMAN	C3a anaphylatoxin chemotactic receptor	8605247	cDNA cloning of a novel G protein-coupled receptor with a large extracellular loop structure.

P40023	EDC2_YEAST	Enhancer of mRNA-decapping protein 2	14562095	Global analysis of protein localization in budding yeast.

Q3U0V2	TRADD_MOUSE	Tumor necrosis factor receptor type 1-associated DEATH domain protein	16702408	Keratin 17 modulates hair follicle cycling in a TNFalpha-dependent fashion.

Q9QZI9	SERC3_MOUSE	Serine incorporator 3	10637174	Identification of a ubiquitous family of membrane proteins and their expression in mouse brain.

O43464	HTRA2_HUMAN	Serine protease HTRA2, mitochondrial	10644717	Characterization of a novel human serine protease that has extensive homology to bacterial heat shock endoprotease HtrA and is regulated by kidney ischemia.

Q05672	RBS1_YEAST	RNA-binding suppressor of PAS kinase protein 1	14562095	Global analysis of protein localization in budding yeast.

Q9WUF4	VAMP8_RAT	Vesicle-associated membrane protein 8	10336434	Mixed and non-cognate SNARE complexes. Characterization of assembly and biophysical properties.

P43884	PLIN1_RAT	Perilipin-1	7505452	Isolation of cDNAs for perilipins A and B: sequence and expression of lipid droplet-associated proteins of adipocytes.

Q9M0G9	AB24B_ARATH	ABC transporter B family member 24, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q9VKY8	SPS2_DROME	Selenide, water dikinase 2	11258485	The class 2 selenophosphate synthetase gene of Drosophila contains a functional mammalian-type SECIS.

Q9US48	GAA1_SCHPO	GPI transamidase component gaa1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P30411	BKRB2_HUMAN	B2 bradykinin receptor	1314587	Cloning and pharmacological characterization of a human bradykinin (BK-2) receptor.

Q56WN1	GLN11_ARATH	Glutamine synthetase cytosolic isozyme 1-1	10482686	Carbon and amino acids reciprocally modulate the expression of glutamine synthetase in Arabidopsis.

Q7Z3T8	ZFY16_HUMAN	Zinc finger FYVE domain-containing protein 16	14613930	Endofin recruits TOM1 to endosomes.

P38961	RRP8_YEAST	Ribosomal RNA-processing protein 8	10864042	Rrp8p is a yeast nucleolar protein functionally linked to Gar1p and involved in pre-rRNA cleavage at site A2.

Q15459	SF3A1_HUMAN	Splicing factor 3A subunit 1	10882114	Functional association of U2 snRNP with the ATP-independent spliceosomal complex E.

Q1XG90	LYS2_CRAVI	Lysozyme 2	17160350	A new lysozyme from the eastern oyster (Crassostrea virginica) indicates adaptive evolution of i-type lysozymes.

P41212	ETV6_HUMAN	Transcription factor ETV6	12590135	The histone deacetylase 9 gene encodes multiple protein isoforms.

Q9Y5E1	PCDB9_HUMAN	Protocadherin beta-9	11322959	The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number.

P15919	RAG1_MOUSE	V(D)J recombination-activating protein 1	8284210	Expression and V(D)J recombination activity of mutated RAG-1 proteins.

Q8K4K2	TRIB3_MOUSE	Tribbles homolog 3	12749859	Mouse NIPK interacts with ATF4 and affects its transcriptional activity.

P17097	ZNF7_HUMAN	Zinc finger protein 7	2106481	cDNA isolation, expression analysis, and chromosomal localization of two human zinc finger genes.

Q8IXJ6	SIRT2_HUMAN	NAD-dependent deacetylase sirtuin-2	12620231	The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase.

P83371	OTOL1_ONCKE	Otolin-1	11856329	Fish otolith contains a unique structural protein, otolin-1.

Q9VUY9	PGM_DROME	Phosphoglucomutase	11560897	The functional impact of Pgm amino acid polymorphism on glycogen content in Drosophila melanogaster.

Q12379	SWM1_YEAST	Anaphase-promoting complex subunit SWM1	12477395	Proteomics analysis identifies new components of the fission and budding yeast anaphase-promoting complexes.

Q9VDG2	RLIP_DROME	RalA-binding protein 1	12775724	RLIP, an effector of the Ral GTPases, is a platform for Cdk1 to phosphorylate epsin during the switch off of endocytosis in mitosis.

P08721	OSTP_RAT	Osteopontin	3024151	Cloning and sequence analysis of rat bone sialoprotein (osteopontin) cDNA reveals an Arg-Gly-Asp cell-binding sequence.

Q12246	LCB4_YEAST	Sphingoid long chain base kinase 4	12493772	Lcb4p is a key regulator of ceramide synthesis from exogenous long chain sphingoid base in Saccharomyces cerevisiae.

O48538	RBOHF_ARATH	Respiratory burst oxidase homolog protein F	12773379	NADPH oxidase AtrbohD and AtrbohF genes function in ROS-dependent ABA signaling in Arabidopsis.

P60324	NANO3_MOUSE	Nanos homolog 3	12947200	Conserved role of nanos proteins in germ cell development.

P48147	PPCE_HUMAN	Prolyl endopeptidase	7959018	Cloning and sequence analysis of the gene encoding human lymphocyte prolyl endopeptidase.

P38238	TRM7_YEAST	tRNA (uridine-2'-O-)-methyltransferase TRM7	11927565	Trm7p catalyses the formation of two 2'-O-methylriboses in yeast tRNA anticodon loop.

Q8K4T5	DUS19_MOUSE	Dual specificity protein phosphatase 19	11959861	A novel dual specificity phosphatase SKRP1 interacts with the MAPK kinase MKK7 and inactivates the JNK MAPK pathway. Implication for the precise regulation of the particular MAPK pathway.

P0A9K9	SLYD_ECOLI	FKBP-type peptidyl-prolyl cis-trans isomerase slyD	8300624	An Escherichia coli protein consisting of a domain homologous to FK506-binding proteins (FKBP) and a new metal binding motif.

P40988	FET4_YEAST	Low-affinity Fe(2+) transport protein	7929320	The FET4 gene encodes the low affinity Fe(II) transport protein of Saccharomyces cerevisiae.

O00899	GAPA_DICDI	Ras GTPase-activating-like protein gapA	11447112	Recruitment of cortexillin into the cleavage furrow is controlled by Rac1 and IQGAP-related proteins.

P53345	YRF13_YEAST	Y' element ATP-dependent helicase protein 1 copies 3/7	9837911	Y'-Help1, a DNA helicase encoded by the yeast subtelomeric Y' element, is induced in survivors defective for telomerase.

Q8VD72	TTC8_MOUSE	Tetratricopeptide repeat protein 8	14520415	Basal body dysfunction is a likely cause of pleiotropic Bardet-Biedl syndrome.

O60102	YOX6_SCHPO	Uncharacterized ABC transporter ATP-binding protein C14F5.06	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P0AAI3	FTSH_ECOLI	ATP-dependent zinc metalloprotease FtsH	7781608	Escherichia coli FtsH is a membrane-bound, ATP-dependent protease which degrades the heat-shock transcription factor sigma 32.

P53355	DAPK1_HUMAN	Death-associated protein kinase 1	10629061	Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis.

Q9R011	PLK3_RAT	Serine/threonine-protein kinase PLK3	10523297	The polo-like protein kinases Fnk and Snk associate with a Ca(2+)- and integrin-binding protein and are regulated dynamically with synaptic plasticity.

Q8NHH9	ATLA2_HUMAN	Atlastin-2	18270207	Atlastin GTPases are required for Golgi apparatus and ER morphogenesis.

Q9FMB6	BIM3_ARATH	Transcription factor BIM3	15680330	A new class of transcription factors mediates brassinosteroid- regulated gene expression in Arabidopsis.

O45406	KBP3_CAEEL	Kinetochore-binding protein 3	15371340	A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension.

P53845	YIF1_YEAST	Protein transport protein YIF1	11157978	Erv41p and Erv46p: new components of COPII vesicles involved in transport between the ER and Golgi complex.

P84022	SMAD3_HUMAN	Mothers against decapentaplegic homolog 3	15647271	The integral inner nuclear membrane protein MAN1 physically interacts with the R-Smad proteins to repress signaling by the transforming growth factor-{beta} superfamily of cytokines.

Q15561	TEAD4_HUMAN	Transcriptional enhancer factor TEF-3	19324877	TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition.

P77364	GLXK1_ECOLI	Glycerate kinase 1	10601204	Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.

O76554	ACH4_CAEEL	Acetylcholine receptor subunit alpha-type des-2	15932871	RIC-3 affects properties and quantity of nicotinic acetylcholine receptors via a mechanism that does not require the coiled-coil domains.

Q99496	RING2_HUMAN	E3 ubiquitin-protein ligase RING2	16943429	Polycomb group and SCF ubiquitin ligases are found in a novel BCOR complex that is recruited to BCL6 targets.

O35762	NKX61_RAT	Homeobox protein Nkx-6.1	10567713	Cloning and DNA-binding properties of the rat pancreatic beta-cell- specific factor Nkx6.1.

O43524	FOXO3_HUMAN	Forkhead box protein O3	18593906	Pim kinases promote cell cycle progression by phosphorylating and down-regulating p27Kip1 at the transcriptional and posttranscriptional levels.

Q60876	4EBP1_MOUSE	Eukaryotic translation initiation factor 4E-binding protein 1	7629182	Control of PHAS-I by insulin in 3T3-L1 adipocytes. Synthesis, degradation, and phosphorylation by a rapamycin-sensitive and mitogen- activated protein kinase-independent pathway.

Q8IN44	TOTA_DROME	Protein Turandot A	11369236	A humoral stress response in Drosophila.

Q12841	FSTL1_HUMAN	Follistatin-related protein 1	7957230	Characterization of a rat C6 glioma-secreted follistatin-related protein (FRP). Cloning and sequence of the human homologue.

P36157	MSA2_YEAST	Putative transcriptional activator MSA2	14562095	Global analysis of protein localization in budding yeast.

Q17770	PDI2_CAEEL	Protein disulfide-isomerase 2	12036960	The exoskeleton collagens in Caenorhabditis elegans are modified by prolyl 4-hydroxylases with unique combinations of subunits.

Q14980	NUMA1_HUMAN	Nuclear mitotic apparatus protein 1	1541630	NuMA: an unusually long coiled-coil related protein in the mammalian nucleus.

O14494	LPP1_HUMAN	Lipid phosphate phosphohydrolase 1	9305923	Cloning and characterization of two human isozymes of Mg2+- independent phosphatidic acid phosphatase.

Q9DCV3	DGAT2_MOUSE	Diacylglycerol O-acyltransferase 2	14668353	Lipopenia and skin barrier abnormalities in DGAT2-deficient mice.

Q8NFD5	ARI1B_HUMAN	AT-rich interactive domain-containing protein 1B	12200431	Largest subunits of the human SWI/SNF chromatin-remodeling complex promote transcriptional activation by steroid hormone receptors.

P61983	1433G_RAT	14-3-3 protein gamma	8381897	Molecular cloning of rat cDNAs for beta and gamma subtypes of 14-3-3 protein and developmental changes in expression of their mRNAs in the nervous system.

Q9UTE1	YFMD_SCHPO	Probable 6-phosphofructo-2-kinase C222.13c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q61753	SERA_MOUSE	D-3-phosphoglycerate dehydrogenase	19114063	Impaired neurogenesis in embryonic spinal cord of Phgdh knockout mice, a serine deficiency disorder model.

P89114	SAE3_YEAST	Pachytene arrest protein SAE3	9215889	Mutations in Saccharomyces cerevisiae that block meiotic prophase chromosome metabolism and confer cell cycle arrest at pachytene identify two new meiosis-specific genes SAE1 and SAE3.

P50617	DEND_RAT	Dendrin	9073398	Prominent dendritic localization in forebrain neurons of a novel mRNA and its product, dendrin.

Q04178	HPRT_YEAST	Hypoxanthine-guanine phosphoribosyltransferase	7035445	Studies of the kinetic mechanism of hypoxanthine-guanine phosphoribosyltransferase from yeast.

Q9NP58	ABCB6_HUMAN	ATP-binding cassette sub-family B member 6, mitochondrial	17006453	Identification of a mammalian mitochondrial porphyrin transporter.

P56677	ST14_MOUSE	Suppressor of tumorigenicity 14 protein homolog	10199918	Cloning and chromosomal mapping of a gene isolated from thymic stromal cells encoding a new mouse type II membrane serine protease, epithin, containing four LDL receptor modules and two CUB domains.

Q9P7I2	KCC1_SCHPO	Calcium/calmodulin-dependent protein kinase type I	10617667	Cloning of a calmodulin kinase I homologue from Schizosaccharomyces pombe.

Q9W0M2	GR61A_DROME	Putative gustatory receptor 61a	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

P10662	RT01_YEAST	37S ribosomal protein MRP1, mitochondrial	11278769	Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues.

Q70KY4	FOXO6_MOUSE	Forkhead box protein O6	12857750	FoxO6, a novel member of the FoxO class of transcription factors with distinct shuttling dynamics.

P23512	FOXA1_RAT	Hepatocyte nuclear factor 3-alpha	17220277	Physical and functional interactions between homeodomain NKX2.1 and winged helix/forkhead FOXA1 in lung epithelial cells.

P56546	CTBP2_MOUSE	C-terminal-binding protein 2	18483224	Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex.

O08680	EPHA3_RAT	Ephrin type-A receptor 3	9458884	IL-1 beta alters the expression of the receptor tyrosine kinase gene r-EphA3 in neonatal rat cardiomyocytes.

Q05481	ZNF91_HUMAN	Zinc finger protein 91	2023909	The evolutionarily conserved Kruppel-associated box domain defines a subfamily of eukaryotic multifingered proteins.

Q92622	RUBIC_HUMAN	Run domain Beclin-1 interacting and cystein-rich containing protein	19270696	Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages.

O60942	MCE1_HUMAN	mRNA-capping enzyme	9473487	Cloning and characterization of two human cDNAs encoding the mRNA capping enzyme.

Q16655	MAR1_HUMAN	Melanoma antigen recognized by T-cells 1	8170938	Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor.

O75004	CDC24_SCHPO	Cell division control protein 24	9891039	Fission yeast cdc24 is a replication factor C- and proliferating cell nuclear antigen-interacting factor essential for S-phase completion.

Q9QZ23	NFU1_MOUSE	NFU1 iron-sulfur cluster scaffold homolog, mitochondrial	11342215	Identification of human and mouse HIRA-interacting protein-5 (HIRIP5), two mammalian representatives in a family of phylogenetically conserved proteins with a role in the biogenesis of Fe/S proteins.

P18115	THAB_XENLA	Thyroid hormone receptor alpha-B	8969201	Functional characterization of a mutant thyroid hormone receptor in Xenopus laevis.

Q12369	SFI1_YEAST	Protein SFI1	10455233	Deletion of SFI1, a novel suppressor of partial Ras-cAMP pathway deficiency in the yeast Saccharomyces cerevisiae, causes G(2) arrest.

Q92900	RENT1_HUMAN	Regulator of nonsense transcripts 1	11544179	Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay.

Q9UJ90	KCE1L_HUMAN	Potassium voltage-gated channel subfamily E member 1-like protein	10493825	KCNE1-like gene is deleted in AMME contiguous gene syndrome: Identification and characterization of the human and mouse homologs.

P0ABN1	KDGL_ECOLI	Diacylglycerol kinase	2984194	sn-1,2-Diacylglycerol kinase of Escherichia coli. Purification, reconstitution, and partial amino- and carboxyl-terminal analysis.

P35582	FOXA1_MOUSE	Hepatocyte nuclear factor 3-alpha	15748903	FoxA1 binding to the MMTV LTR modulates chromatin structure and transcription.

P39001	UME6_YEAST	Transcriptional regulatory protein UME6	7926768	UME6 is a key regulator of nitrogen repression and meiotic development.

P38911	FKBP3_YEAST	FK506-binding nuclear protein	8051210	Yeast NPI46 encodes a novel prolyl cis-trans isomerase that is located in the nucleolus.

Q6QHF9	PAOX_HUMAN	Peroxisomal N(1)-acetyl-spermine/spermidine oxidase	12477380	Genomic identification and biochemical characterization of the mammalian polyamine oxidase involved in polyamine back-conversion.

Q8WWI5	CTL1_HUMAN	Choline transporter-like protein 1	10677542	An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteins.

Q8R1B4	EIF3C_MOUSE	Eukaryotic translation initiation factor 3 subunit C	17581632	Reconstitution reveals the functional core of mammalian eIF3.

Q8NG41	NPB_HUMAN	Neuropeptide B	12401809	Identification of natural ligands for the orphan G protein-coupled receptors GPR7 and GPR8.

P08294	SODE_HUMAN	Extracellular superoxide dismutase [Cu-Zn]	8034674	10-fold increase in human plasma extracellular superoxide dismutase content caused by a mutation in heparin-binding domain.

Q14974	IMB1_HUMAN	Importin subunit beta-1	9405152	Interactions between HIV Rev and nuclear import and export factors: the Rev nuclear localisation signal mediates specific binding to human importin-beta.

Q9UER7	DAXX_HUMAN	Death domain-associated protein 6	12140263	Daxx and histone deacetylase II associate with chromatin through an interaction with core histones and the chromatin-associated protein Dek.

P42834	MDJ2_YEAST	Mitochondrial DnaJ homolog 2	16027163	The import motor of the yeast mitochondrial TIM23 preprotein translocase contains two different J proteins, Tim14 and Mdj2.

Q9FXF2	RKF1_ARATH	Probable LRR receptor-like serine/threonine-protein kinase RFK1	9687063	Identification by PCR of receptor-like protein kinases from Arabidopsis flowers.

P06104	UBC2_YEAST	Ubiquitin-conjugating enzyme E2 2	10880451	Two RING finger proteins mediate cooperation between ubiquitin- conjugating enzymes in DNA repair.

Q09772	RDH54_SCHPO	Meiotic recombination protein rdh54	14551247	Schizosaccharomyces pombe Rdh54 (TID1) acts with Rhp54 (RAD54) to repair meiotic double-strand breaks.

O36027	WSP1_SCHPO	Wiskott-Aldrich syndrome protein homolog 1	11076964	Fission yeast myosin-I, Myo1p, stimulates actin assembly by Arp2/3 complex and shares functions with WASp.

Q04406	EMI1_YEAST	Early meiotic induction protein 1	12586695	Large-scale functional genomic analysis of sporulation and meiosis in Saccharomyces cerevisiae.

Q9CW42	MOSC1_MOUSE	MOSC domain-containing protein 1, mitochondrial	12865426	Proteomic analysis of the mouse liver mitochondrial inner membrane.

Q9Z2S7	T22D3_MOUSE	TSC22 domain family protein 3	9430225	A new dexamethasone-induced gene of the leucine zipper family protects T lymphocytes from TCR/CD3-activated cell death.

Q99640	PMYT1_HUMAN	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	9268380	Human Myt1 is a cell cycle-regulated kinase that inhibits Cdc2 but not Cdk2 activity.

O22476	BRI1_ARATH	Protein BRASSINOSTEROID INSENSITIVE 1	15548744	Heterodimerization and endocytosis of Arabidopsis brassinosteroid receptors BRI1 and AtSERK3 (BAK1).

Q09826	SDS23_SCHPO	Protein sds23/moc1	16273369	Moc3, a novel Zn finger type protein involved in sexual development, ascus formation, and stress response of Schizosaccharomyces pombe.

P39950	CCNG1_RAT	Cyclin-G1	8336937	Cyclin G: a new mammalian cyclin with homology to fission yeast Cig1.

Q86BJ3	PIPE_DROME	Heparan sulfate 2-O-sulfotransferase pipe	11076773	Windbeutel is required for function and correct subcellular localization of the Drosophila patterning protein Pipe.

P04182	OAT_RAT	Ornithine aminotransferase, mitochondrial	3840476	Sequence of the precursor to rat ornithine aminotransferase deduced from a cDNA clone.

A2ARA8	ITA8_MOUSE	Integrin alpha-8	17537792	The ECM protein nephronectin promotes kidney development via integrin alpha8beta1-mediated stimulation of Gdnf expression.

P61326	MGN_HUMAN	Protein mago nashi homolog	18026120	PYM binds the cytoplasmic exon-junction complex and ribosomes to enhance translation of spliced mRNAs.

B1Q005	MBOA4_RAT	Ghrelin O-acyltransferase	18443287	Ghrelin octanoylation mediated by an orphan lipid transferase.

P19313	CYTS_RAT	Cystatin-S	3263967	Cloning and sequencing of cDNA encoding a rat salivary cysteine proteinase inhibitor inducible by beta-adrenergic agonists.

Q6PST4	ATLA1_RAT	Atlastin-1	16537571	SPG3A protein atlastin-1 is enriched in growth cones and promotes axon elongation during neuronal development.

Q9U1Y5	CHK2_CAEEL	Serine/threonine-protein kinase chk-2	11158318	Critical role of Caenorhabditis elegans homologs of cds1 (Chk2)- related kinases in meiotic recombination.

Q01780	EXOSX_HUMAN	Exosome component 10	18172165	Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'.

Q19266	KPC3_CAEEL	Protein kinase C-like 3	11134025	Structural properties and mechanisms that govern association of C kinase adapter 1 with protein kinase C3 and the cell periphery.

Q12523	YP247_YEAST	WD repeat-containing protein YPL247C	14562095	Global analysis of protein localization in budding yeast.

Q15800	ERG25_HUMAN	C-4 methylsterol oxidase	8663358	Characterization of yeast methyl sterol oxidase (ERG25) and identification of a human homologue.

O60139	UBP4_SCHPO	Probable ubiquitin carboxyl-terminal hydrolase 4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P24781	BRAC_XENLA	Brachyury protein	11869292	Xenopus Brachyury regulates mesodermal expression of Zic3, a gene controlling left-right asymmetry.

Q8BGY6	B3GN5_MOUSE	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5	11384981	Cloning of a mouse beta 1,3 N-acetylglucosaminyltransferase GlcNAc(beta 1,3)Gal(beta 1,4)Glc-ceramide synthase gene encoding the key regulator of lacto-series glycolipid biosynthesis.

Q99K48	NONO_MOUSE	Non-POU domain-containing octamer-binding protein	8626664	The transcription factor Spi-1/PU.1 binds RNA and interferes with the RNA-binding protein p54nrb.

Q09808	SMN1_SCHPO	Survival motor neuron-like protein 1	10749974	Characterization of the Schizosaccharomyces pombe orthologue of the human survival motor neuron (SMN) protein.

P32255	TBA_DICDI	Tubulin alpha chain	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P33332	SEC3_YEAST	Exocyst complex component SEC3	8978675	The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae.

P07550	ADRB2_HUMAN	Beta-2 adrenergic receptor	19424180	The deubiquitinases USP33 and USP20 coordinate beta2 adrenergic receptor recycling and resensitization.

Q46893	ISPD_ECOLI	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	10518523	Cytidine 5'-triphosphate-dependent biosynthesis of isoprenoids: YgbP protein of Escherichia coli catalyzes the formation of 4- diphosphocytidyl-2-C-methylerythritol.

Q8T133	TORA_DICDI	Protein tortoise	11157987	Tortoise, a novel mitochondrial protein, is required for directional responses of Dictyostelium in chemotactic gradients.

P48234	NOL10_YEAST	Ribosome biogenesis protein ENP2	14690591	Assigning function to yeast proteins by integration of technologies.

P09040	DSK_DROME	Drosulfakinins	17632121	The drosulfakinin 0 (DSK 0) peptide encoded in the conserved Dsk gene affects adult Drosophila melanogaster crop contractions.

P06132	DCUP_HUMAN	Uroporphyrinogen decarboxylase	1634232	Characterization of a new mutation (R292G) and a deletion at the human uroporphyrinogen decarboxylase locus in two patients with hepatoerythropoietic porphyria.

P34947	GRK5_HUMAN	G protein-coupled receptor kinase 5	7685906	Cloning and expression of GRK5: a member of the G protein-coupled receptor kinase family.

Q70KG5	RAF1A_WHEAT	Protein RAFTIN 1A	14612572	The classical Ubisch bodies carry a sporophytically produced structural protein (RAFTIN) that is essential for pollen development.

Q9SB60	IPT4_ARATH	Adenylate isopentenyltransferase 4	11479373	Identification of plant cytokinin biosynthetic enzymes as dimethylallyl diphosphate:ATP/ADP isopentenyltransferases.

P81916	OR33C_DROME	Odorant receptor 33c	10069338	A novel family of divergent seven-transmembrane proteins: candidate odorant receptors in Drosophila.

Q8LPK5	CESA8_ARATH	Cellulose synthase A catalytic subunit 8 [UDP-forming]	17351116	Impairment of cellulose synthases required for Arabidopsis secondary cell wall formation enhances disease resistance.

O14678	ABCD4_HUMAN	ATP-binding cassette sub-family D member 4	9266848	Primary structure of human PMP69, a putative peroxisomal ABC- transporter.

O55171	ACOT2_RAT	Acyl-coenzyme A thioesterase 2, mitochondrial	9445388	Molecular cloning and characterization of a mitochondrial peroxisome proliferator-induced acyl-CoA thioesterase from rat liver.

P40352	RAD26_YEAST	DNA repair and recombination protein RAD26	7957102	RAD26, the functional S. cerevisiae homolog of the Cockayne syndrome B gene ERCC6.

P46607	HGL2_ARATH	Homeobox-leucine zipper protein GLABRA 2	11844112	Entopically additive expression of GLABRA2 alters the frequency and spacing of trichome initiation.

Q5TD94	RSH4A_HUMAN	Radial spoke head protein 4 homolog A	19200523	Mutations in radial spoke head protein genes RSPH9 and RSPH4A cause primary ciliary dyskinesia with central-microtubular-pair abnormalities.

O75569	PRKRA_HUMAN	Interferon-inducible double stranded RNA-dependent protein kinase activator A	17452327	Human TRBP and PACT directly interact with each other and associate with dicer to facilitate the production of small interfering RNA.

Q96PU4	UHRF2_HUMAN	E3 ubiquitin-protein ligase UHRF2	14741369	NIRF is a ubiquitin ligase that is capable of ubiquitinating PCNP, a PEST-containing nuclear protein.

P20457	PRI2_YEAST	DNA primase large subunit	3061469	The yeast DNA polymerase-primase complex: genes and proteins.

Q62108	DLG4_MOUSE	Disks large homolog 4	19474308	TMEM16B, a novel protein with calcium-dependent chloride channel activity, associates with a presynaptic protein complex in photoreceptor terminals.

O95199	RCBT2_HUMAN	RCC1 and BTB domain-containing protein 2	9806834	cDNA cloning, gene characterization and 13q14.3 chromosomal assignment of CHC1-L, a chromosome condensation regulator-like guanine nucleotide exchange factor.

P23434	GCSH_HUMAN	Glycine cleavage system H protein, mitochondrial	1671321	The glycine cleavage system: structure of a cDNA encoding human H- protein, and partial characterization of its gene in patients with hyperglycinemias.

Q9SAK5	APL_ARATH	Myb family transcription factor APL	14614507	APL regulates vascular tissue identity in Arabidopsis.

O15265	ATX7_HUMAN	Ataxin-7	11371513	Ataxin-7 interacts with a Cbl-associated protein that it recruits into neuronal intranuclear inclusions.

Q54MZ3	CDC20_DICDI	Anaphase-promoting complex subunit cdc20	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q9JJJ7	PORCN_MOUSE	Probable protein-cysteine N-palmitoyltransferase porcupine	10866835	The evolutionarily conserved porcupine gene family is involved in the processing of the Wnt family.

Q93ZY2	ROGF1_ARATH	Rop guanine nucleotide exchange factor 1	15980860	A new family of RhoGEFs activates the Rop molecular switch in plants.

P63000	RAC1_HUMAN	Ras-related C3 botulinum toxin substrate 1	10954424	The mammalian homologue of the Caenorhabditis elegans polarity protein PAR-6 is a binding partner for the Rho GTPases Cdc42 and Rac1.

Q9R1L5	MAST1_MOUSE	Microtubule-associated serine/threonine-protein kinase 1	10404183	Interactions between beta 2-syntrophin and a family of microtubule- associated serine/threonine kinases.

Q8N1F8	S11IP_HUMAN	Serine/threonine-protein kinase 11-interacting protein	11741830	LIP1, a cytoplasmic protein functionally linked to the Peutz-Jeghers syndrome kinase LKB1.

Q06187	BTK_HUMAN	Tyrosine-protein kinase BTK	8013627	An exon-skipping mutation in the btk gene of a patient with X-linked agammaglobulinemia and isolated growth hormone deficiency.

P36024	SIS2_YEAST	Protein SIS2	9636153	The yeast halotolerance determinant Hal3p is an inhibitory subunit of the Ppz1p Ser/Thr protein phosphatase.

Q6W2J9	BCOR_HUMAN	BCL-6 corepressor	19578371	BCOR regulates mesenchymal stem cell function by epigenetic mechanisms.

P43490	NAMPT_HUMAN	Nicotinamide phosphoribosyltransferase	8289818	Cloning and characterization of the cDNA encoding a novel human pre- B-cell colony-enhancing factor.

Q9VKN7	AURKB_DROME	Serine/threonine-protein kinase Ial	11266459	Drosophila aurora B kinase is required for histone H3 phosphorylation and condensin recruitment during chromosome condensation and to organize the central spindle during cytokinesis.

Q13043	STK4_HUMAN	Serine/threonine-protein kinase 4	15109305	Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras.

P54120	AIG1_ARATH	Protein AIG1	8742710	Isolation of Arabidopsis genes that differentiate between resistance responses mediated by the RPS2 and RPM1 disease resistance genes.

Q9UK97	FBX9_HUMAN	F-box only protein 9	10531037	A family of mammalian F-box proteins.

O14495	LPP3_HUMAN	Lipid phosphate phosphohydrolase 3	9305923	Cloning and characterization of two human isozymes of Mg2+- independent phosphatidic acid phosphatase.

Q9VVT2	INDY1_DROME	Protein I'm not dead yet	12186628	Functional identity of Drosophila melanogaster Indy as a cation- independent, electroneutral transporter for tricarboxylic acid-cycle intermediates.

O08556	CCR5_RAT	C-C chemokine receptor type 5	9670989	Cloning of rat HIV-1-chemokine coreceptor CKR5 from microglia and upregulation of its mRNA in ischemic and endotoxinemic rat brain.

P93031	GMD2_ARATH	GDP-mannose 4,6 dehydratase 2	9050909	The MUR1 gene of Arabidopsis thaliana encodes an isoform of GDP-D- mannose-4,6-dehydratase, catalyzing the first step in the de novo synthesis of GDP-L-fucose.

Q92316	OST5_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST5	9405463	The highly conserved Stt3 protein is a subunit of the yeast oligosaccharyltransferase and forms a subcomplex with Ost3p and Ost4p.

Q39258	VATE1_ARATH	V-type proton ATPase subunit E1	16618929	Mapping the Arabidopsis organelle proteome.

P52824	DGKQ_HUMAN	Diacylglycerol kinase theta	17664281	Cyclic AMP-stimulated interaction between steroidogenic factor 1 and diacylglycerol kinase theta facilitates induction of CYP17.

O88842	FGD3_MOUSE	FYVE, RhoGEF and PH domain-containing protein 3	10721717	Isolation, characterization, and mapping of the mouse Fgd3 gene, a new faciogenital dysplasia (FGD1; Aarskog syndrome) gene homologue.

P0A9P6	DEAD_ECOLI	Cold-shock DEAD box protein A	8552679	Cold shock induces a major ribosomal-associated protein that unwinds double-stranded RNA in Escherichia coli.

Q12136	SAS10_YEAST	Something about silencing protein 10	9611201	Sir- and silencer-independent disruption of silencing in Saccharomyces by Sas10p.

Q96247	AUX1_ARATH	Auxin transporter protein 1	11641271	Localization of the auxin permease AUX1 suggests two functionally distinct hormone transport pathways operate in the Arabidopsis root apex.

Q9UHV9	PFD2_HUMAN	Prefoldin subunit 2	9630229	Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin.

P10275	ANDR_HUMAN	Androgen receptor	3353727	Cloning of human androgen receptor complementary DNA and localization to the X chromosome.

P17301	ITA2_HUMAN	Integrin alpha-2	16754960	Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins.

Q9EQG9	C43BP_MOUSE	Collagen type IV alpha-3-binding protein	11007769	Goodpasture antigen-binding protein, the kinase that phosphorylates the Goodpasture antigen, is an alternatively spliced variant implicated in autoimmune pathogenesis.

P03406	NEF_HV1BR	Protein Nef	11861836	Human immunodeficiency virus type 1 Nef binds to tumor suppressor p53 and protects cells against p53-mediated apoptosis.

Q8TDB6	DTX3L_HUMAN	E3 ubiquitin-protein ligase DTX3L	19818714	BBAP monoubiquitylates histone H4 at lysine 91 and selectively modulates the DNA damage response.

P46947	CWC26_YEAST	Pre-mRNA-splicing factor CWC26	15565172	Proteomic analysis identifies a new complex required for nuclear pre- mRNA retention and splicing.

O08919	NUMBL_MOUSE	Numb-like protein	17174898	Postnatal deletion of Numb/Numblike reveals repair and remodeling capacity in the subventricular neurogenic niche.

Q0WYX8	MDGA1_CHICK	MAM domain-containing glycosylphosphatidylinositol anchor protein 1	16782075	MDGA1, an IgSF molecule containing a MAM domain, heterophilically associates with axon- and muscle-associated binding partners through distinct structural domains.

Q92813	IOD2_HUMAN	Type II iodothyronine deiodinase	9837913	The 3'-untranslated region of human type 2 iodothyronine deiodinase mRNA contains a functional selenocysteine insertion sequence element.

P41407	AZOR_ECOLI	FMN-dependent NADH-azoreductase	11583992	Putative ACP phosphodiesterase gene (acpD) encodes an azoreductase.

Q8WT56	FAR1_LITSI	Fatty-acid and retinol-binding protein 1	12106870	The FAR proteins of filarial nematodes: secretion, glycosylation and lipid binding characteristics.

O14332	REM1_SCHPO	Meiosis-specific cyclin rem1	16024772	A meiosis-specific cyclin regulated by splicing is required for proper progression through meiosis.

P39414	TTDT_ECOLI	L-tartrate/succinate antiporter	17172328	The L-tartrate/succinate antiporter TtdT (YgjE) of L-tartrate fermentation in Escherichia coli.

Q55F68	CYAD_DICDI	Adenylate cyclase, terminal-differentiation specific	10556070	An adenylyl cyclase that functions during late development of Dictyostelium.

P52823	STC1_HUMAN	Stanniocalcin-1	8700837	Human stanniocalcin: a possible hormonal regulator of mineral metabolism.

O60469	DSCAM_HUMAN	Down syndrome cell adhesion molecule	18585357	DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1.

Q9SA76	PPR64_ARATH	Pentatricopeptide repeat-containing protein At1g30610, chloroplastic	15647901	Arabidopsis emb175 and other ppr knockout mutants reveal essential roles for pentatricopeptide repeat (PPR) proteins in plant embryogenesis.

Q9P3A9	YIL5_SCHPO	Uncharacterized protein C1565.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8L735	ISOA2_ARATH	Isoamylase 2, chloroplastic	15743447	Arabidopsis mutants Atisa1 and Atisa2 have identical phenotypes and lack the same multimeric isoamylase, which influences the branch point distribution of amylopectin during starch synthesis.

Q9ERR1	NDEL1_MOUSE	Nuclear distribution protein nudE-like 1	11231056	NudE-L, a novel Lis1-interacting protein, belongs to a family of vertebrate coiled-coil proteins.

Q12427	STB3_YEAST	Protein STB3	14562095	Global analysis of protein localization in budding yeast.

P31213	S5A2_HUMAN	3-oxo-5-alpha-steroid 4-dehydrogenase 2	1944596	Deletion of steroid 5 alpha-reductase 2 gene in male pseudohermaphroditism.

Q8IRJ8	THOC7_DROME	THO complex protein 7	15133499	Genome-wide analysis of mRNAs regulated by the THO complex in Drosophila.

Q9NDH7	GLY2_CAEEL	Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	11937505	The Caenorhabditis elegans gene, gly-2, can rescue the N- acetylglucosaminyltransferase V mutation of Lec4 cells.

Q08932	RSA1_YEAST	Ribosome assembly 1 protein	10567587	Synthetic lethality with conditional dbp6 alleles identifies Rsa1p, a nucleoplasmic protein involved in the assembly of 60S ribosomal subunits.

Q9BST9	RTKN_HUMAN	Rhotekin	15480428	Rho/Rhotekin-mediated NF-kappaB activation confers resistance to apoptosis.

Q9JHW9	AL1A3_MOUSE	Aldehyde dehydrogenase family 1 member A3	10906479	A retinoic acid synthesizing enzyme in ventral retina and telencephalon of the embryonic mouse.

Q03834	MSH6_YEAST	DNA mismatch repair protein MSH6	10347163	A mutation in the MSH6 subunit of the Saccharomyces cerevisiae MSH2- MSH6 complex disrupts mismatch recognition.

P54646	AAPK2_HUMAN	5'-AMP-activated protein kinase catalytic subunit alpha-2	7959015	Characterization and chromosomal localization of the human homologue of a rat AMP-activated protein kinase-encoding gene: a major regulator of lipid metabolism in mammals.

Q9UQ88	CD11A_HUMAN	Cell division protein kinase 11A	12501247	CDK11 complexes promote pre-mRNA splicing.

P55000	SLUR1_HUMAN	Secreted Ly-6/uPAR-related protein 1	8742060	Partial N-terminal amino acid sequence of the anti-neoplastic urinary protein (ANUP) and the anti-tumour effect of the N-terminal nonapeptide of the unique cytokine present in human granulocytes.

Q05471	SWR1_YEAST	Helicase SWR1	15045029	A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin.

Q9Y2B4	T53G5_HUMAN	TP53-target gene 5 protein	10719363	Isolation and characterization of a novel TP53-inducible gene, TP53TG5, which suppresses growth and shows cell cycle-dependent transition of expression.

O60126	TOP3_SCHPO	DNA topoisomerase 3	12724426	Role for the fission yeast RecQ helicase in DNA repair in G2.

O60016	CLR4_SCHPO	Histone-lysine N-methyltransferase, H3 lysine-9 specific	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P17066	HSP76_HUMAN	Heat shock 70 kDa protein 6	2327978	The human heat-shock protein family. Expression of a novel heat- inducible HSP70 (HSP70B') and isolation of its cDNA and genomic DNA.

Q8K1H1	TDRD7_MOUSE	Tudor domain-containing protein 7	17141210	Tudor-related proteins TDRD1/MTR-1, TDRD6 and TDRD7/TRAP: domain composition, intracellular localization, and function in male germ cells in mice.

Q8R515	ZHX1_RAT	Zinc fingers and homeoboxes protein 1	12062805	Rat zinc-fingers and homeoboxes 1 (ZHX1), a nuclear factor-YA- interacting nuclear protein, forms a homodimer.

Q5FWY4	MCM6M_XENLA	Maternal DNA replication licensing factor mcm6	9214647	Licensing of DNA replication by a multi-protein complex of MCM/P1 proteins in Xenopus eggs.

Q12888	TP53B_HUMAN	Tumor suppressor p53-binding protein 1	17525332	ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

Q10990	CDT2_SCHPO	Cell division cycle protein cdt2	12871901	The Schizosaccharomyces pombe cdt2(+) gene, a target of G1-S phase- specific transcription factor complex DSC1, is required for mitotic and premeiotic DNA replication.

Q9VTH4	SCLLA_DROME	Protein scylla	15545626	The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila.

O00303	EIF3F_HUMAN	Eukaryotic translation initiation factor 3 subunit F	9341143	Structure of cDNAs encoding human eukaryotic initiation factor 3 subunits. Possible roles in RNA binding and macromolecular assembly.

O94687	TAS3_SCHPO	RNA-induced transcriptional silencing complex protein tas3	14704433	RNAi-mediated targeting of heterochromatin by the RITS complex.

Q63787	P85A_RAT	Phosphatidylinositol 3-kinase regulatory subunit alpha	8621382	A novel 55-kDa regulatory subunit for phosphatidylinositol 3-kinase structurally similar to p55PIK is generated by alternative splicing of the p85alpha gene.

Q13127	REST_HUMAN	RE1-silencing transcription factor	7871435	The neuron-restrictive silencer factor (NRSF): a coordinate repressor of multiple neuron-specific genes.

P34145	RAC1B_DICDI	Rho-related protein rac1B	15509655	Cellular distribution and functions of wild-type and constitutively activated Dictyostelium PakB.

Q9Y2L1	RRP44_HUMAN	Exosome complex exonuclease RRP44	9562621	Human dis3p, which binds to either GTP- or GDP-Ran, complements Saccharomyces cerevisiae dis3.

Q15646	OASL_HUMAN	59 kDa 2'-5'-oligoadenylate synthase-like protein	9826176	Molecular cloning and characterization of two related and interferon- induced 56-kDa and 30-kDa proteins highly similar to 2'-5' oligoadenylate synthetase.

Q45VV3	YORKI_DROME	Protein yorkie	16096061	The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP.

P62746	RHOB_MOUSE	Rho-related GTP-binding protein RhoB	11353846	RhoB is required to mediate apoptosis in neoplastically transformed cells after DNA damage.

P00813	ADA_HUMAN	Adenosine deaminase	11772392	Regulation of epithelial and lymphocyte cell adhesion by adenosine deaminase-CD26 interaction.

Q9ULX7	CAH14_HUMAN	Carbonic anhydrase 14	10512682	Human carbonic anhydrase XIV (CA14): cDNA cloning, mRNA expression, and mapping to chromosome 1.

Q9SRL5	FRI2_ARATH	Ferritin-2, chloroplastic	11672431	Structure and differential expression of the four members of the Arabidopsis thaliana ferritin gene family.

P15806	TFE2_MOUSE	Transcription factor E2-alpha	9409784	The mUBC9 murine ubiquitin conjugating enzyme interacts with the E2A transcription factors.

Q39108	GGR_ARATH	Geranylgeranyl pyrophosphate synthase-related protein, chloroplastic	10759500	Five geranylgeranyl diphosphate synthases expressed in different organs are localized into three subcellular compartments in Arabidopsis.

O22609	DEGP1_ARATH	Protease Do-like 1, chloroplastic	9507020	Identification and characterization of DegP, a serine protease associated with the luminal side of the thylakoid membrane.

Q9VEZ5	IKKB_DROME	Inhibitor of nuclear factor kappa-B kinase subunit beta	11018014	A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity.

O70250	PGAM2_MOUSE	Phosphoglycerate mutase 2	11250083	Mouse phosphoglycerate mutase M and B isozymes: cDNA cloning, enzyme activity assay and mapping.

P55769	NH2L1_HUMAN	NHP2-like protein 1	17412961	Binding of the human Prp31 Nop domain to a composite RNA-protein platform in U4 snRNP.

Q8K0L9	ZBT20_MOUSE	Zinc finger and BTB domain-containing protein 20	11744704	Characterization of two novel nuclear BTB/POZ domain zinc finger isoforms. Association with differentiation of hippocampal neurons, cerebellar granule cells, and macroglia.

P63104	1433Z_HUMAN	14-3-3 protein zeta/delta	16114898	14-3-3 protein interacts with nuclear localization sequence of forkhead transcription factor FoxO4.

P54356	TSG_DROME	Protein twisted gastrulation	11260716	Twisted gastrulation is a conserved extracellular BMP antagonist.

Q9HE01	YKP3_SCHPO	Uncharacterized protein C589.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9VZZ9	DOS_DROME	Protein daughter of sevenless	12128212	SH3 domain-mediated binding of the Drk protein to Dos is an important step in signaling of Drosophila receptor tyrosine kinases.

P01617	KV204_HUMAN	Ig kappa chain V-II region TEW	4596149	Amino acid sequence of a kappa Bence Jones protein from a case of primary amyloidosis.

Q9NFZ3	GBGE_DROME	Guanine nucleotide-binding protein subunit gamma-e	10608815	A novel Ggamma isolated from Drosophila constitutes a visual G protein gamma subunit of the fly compound eye.

O74541	YCV2_SCHPO	Uncharacterized transcriptional regulatory protein C777.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P29536	LMOD1_HUMAN	Leiomodin-1	2026759	Cloning and sequencing of a novel 64-kDa autoantigen recognized by patients with autoimmune thyroid disease.

Q10567	AP1B1_HUMAN	AP-1 complex subunit beta-1	7987321	Characterization of a new member of the human beta-adaptin gene family from chromosome 22q12, a candidate meningioma gene.

Q99466	NOTC4_HUMAN	Neurogenic locus notch homolog protein 4	9168133	Gene organization of human NOTCH4 and (CTG)n polymorphism in this human counterpart gene of mouse proto-oncogene Int3.

Q9R1C7	PR40A_MOUSE	Pre-mRNA-processing factor 40 homolog A	16391387	Interaction of the nuclear matrix protein NAKAP with HypA and huntingtin: implications for nuclear toxicity in Huntington's disease pathogenesis.

Q7KRW1	TRC8_DROME	Protein TRC8 homolog	15735686	Growth suppression induced by the TRC8 hereditary kidney cancer gene is dependent upon JAB1/CSN5.

P48966	MPIP2_RAT	M-phase inducer phosphatase 2	8156993	Cdc25A is a novel phosphatase functioning early in the cell cycle.

Q14642	I5P1_HUMAN	Type I inositol-1,4,5-trisphosphate 5-phosphatase	8006039	Characterization of a cDNA encoding the 43-kDa membrane-associated inositol-polyphosphate 5-phosphatase.

Q9JM80	PAG1_RAT	Phosphoprotein associated with glycosphingolipid-enriched microdomains 1	11859092	Transmembrane phosphoprotein Csk-binding protein/phosphoprotein associated with glycosphingolipid-enriched microdomains as a negative feedback regulator of mast cell signaling through the FcepsilonRI.

Q8GXR9	DHNA_ARATH	Probable NADH dehydrogenase, chloroplastic/mitochondrial	16414959	Tocopherol cyclase (VTE1) localization and vitamin E accumulation in chloroplast plastoglobule lipoprotein particles.

Q94130	WRT8_CAEEL	Warthog protein 8	8689684	Hedgehog patterning activity: role of a lipophilic modification mediated by the carboxy-terminal autoprocessing domain.

O42817	RSSA_CANAL	40S ribosomal protein S0	9579059	A Candida albicans 37 kDa polypeptide with homology to the laminin receptor is a component of the translational machinery.

P80428	ARP4_YEAST	Actin-related protein 4	10911987	Multiple links between the NuA4 histone acetyltransferase complex and epigenetic control of transcription.

Q39022	MPK2_ARATH	Mitogen-activated protein kinase 2	8130795	Characterization of two cDNAs that encode MAP kinase homologues in Arabidopsis thaliana and analysis of the possible role of auxin in activating such kinase activities in cultured cells.

Q01608	SPE4_CAEEL	Presenilin spe-4	9819355	The presenilin protein family member SPE-4 localizes to an ER/Golgi derived organelle and is required for proper cytoplasmic partitioning during Caenorhabditis elegans spermatogenesis.

P23255	TAF2_YEAST	Transcription initiation factor TFIID subunit 2	12138208	Molecular characterization of Saccharomyces cerevisiae TFIID.

Q06152	YL271_YEAST	Uncharacterized protein YLR271W	14562095	Global analysis of protein localization in budding yeast.

P36084	MUD2_YEAST	Splicing factor MUD2	7926772	The yeast MUD2 protein: an interaction with PRP11 defines a bridge between commitment complexes and U2 snRNP addition.

Q14534	ERG1_HUMAN	Squalene monooxygenase	9286711	Localization of the squalene epoxidase gene (SQLE) to human chromosome region 8q24.1.

Q8INV7	TOTE_DROME	Protein Turandot E	11409894	A family of Turandot-related genes in the humoral stress response of Drosophila.

Q10185	ABC2_SCHPO	ATP-binding cassette transporter abc2	16849797	A survey of all 11 ABC transporters in fission yeast: two novel ABC transporters are required for red pigment accumulation in a Schizosaccharomyces pombe adenine biosynthetic mutant.

P38111	ATR_YEAST	Serine/threonine-protein kinase MEC1	11140636	A role for Saccharomyces cerevisiae histone H2A in DNA repair.

P29973	CNGA1_HUMAN	cGMP-gated cation channel alpha-1	7479749	Mutations in the gene encoding the alpha subunit of the rod cGMP- gated channel in autosomal recessive retinitis pigmentosa.

P32584	STE14_YEAST	Protein-S-isoprenylcysteine O-methyltransferase	8212897	Isolation and DNA sequence of the STE14 gene encoding farnesyl cysteine: carboxyl methyltransferase.

P36639	8ODP_HUMAN	7,8-dihydro-8-oxoguanine triphosphatase	8226881	Cloning and expression of cDNA for a human enzyme that hydrolyzes 8- oxo-dGTP, a mutagenic substrate for DNA synthesis.

Q7SIE0	ARLY1_MELGA	Delta-1 crystallin	11258884	Structural studies of duck delta 1 and delta 2 crystallin suggest conformational changes occur during catalysis.

Q10452	GSK3_SCHPO	Protein kinase gsk3	8524294	Schizosaccharomyces pombe skp1+ encodes a protein kinase related to mammalian glycogen synthase kinase 3 and complements a cdc14 cytokinesis mutant.

Q9UI17	M2GD_HUMAN	Dimethylglycine dehydrogenase, mitochondrial	11231903	Cloning of dimethylglycine dehydrogenase and a new human inborn error of metabolism, dimethylglycine dehydrogenase deficiency.

D2XNR0	FLOT3_MEDTR	Flotillin-like protein 3	20018678	Plant flotillins are required for infection by nitrogen-fixing bacteria.

O09114	PTGDS_MOUSE	Prostaglandin-H2 D-isomerase	10781097	Prostaglandin D synthase gene is involved in the regulation of non- rapid eye movement sleep.

B7FDP2	SCX39_CENSU	Toxin Css39.8	19631296	Solution structure of Cn5, a crustacean toxin found in the venom of the scorpions Centruroides noxius and Centruroides suffusus suffusus.

P62158	CALM_HUMAN	Calmodulin	11807546	Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin.

P01584	IL1B_HUMAN	Interleukin-1 beta	1919436	Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human mast cell chymase.

Q8WY07	CTR3_HUMAN	Cationic amino acid transporter 3	11591158	Human cationic amino acid transporter hCAT-3 is preferentially expressed in peripheral tissues.

P48598	IF4E_DROME	Eukaryotic translation initiation factor 4E	14685270	Drosophila Cup is an eIF4E-binding protein that functions in Smaug- mediated translational repression.

P07339	CATD_HUMAN	Cathepsin D	3927292	Cloning and sequence analysis of cDNA for human cathepsin D.

P36106	BYE1_YEAST	Transcription factor BYE1	17142463	Proteome-wide analysis in Saccharomyces cerevisiae identifies several PHD fingers as novel direct and selective binding modules of histone H3 methylated at either lysine 4 or lysine 36.

P47736	RPGP1_HUMAN	Rap1 GTPase-activating protein 1	18309292	The Rap-RapGAP complex: GTP hydrolysis without catalytic glutamine and arginine residues.

Q9M5P3	CCDA_ARATH	Cytochrome c-type biogenesis ccda-like chloroplastic protein	15159384	A homolog of prokaryotic thiol disulfide transporter CcdA is required for the assembly of the cytochrome b6f complex in Arabidopsis chloroplasts.

O75618	DEDD_HUMAN	Death effector domain-containing protein	9832420	DEFT, a novel death effector domain-containing molecule predominantly expressed in testicular germ cells.

Q92784	DPF3_HUMAN	Zinc finger protein DPF3	8812431	The d4 gene family in the human genome.

Q91620	NOD2A_XENLA	Nodal homolog 2-A	8939607	Signalling by TGF-beta family members: short-range effects of Xnr-2 and BMP-4 contrast with the long-range effects of activin.

Q12154	GET3_YEAST	ATPase GET3	18724936	The GET complex mediates insertion of tail-anchored proteins into the ER membrane.

P40463	VHS2_YEAST	Protein VHS2	14562095	Global analysis of protein localization in budding yeast.

Q9FL69	AGD5_ARATH	Probable ADP-ribosylation factor GTPase-activating protein AGD5	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

P40645	SOX6_MOUSE	Transcription factor SOX-6	10996314	Characterization of Solt, a novel SoxLZ/Sox6 binding protein expressed in adult mouse testis.

Q92542	NICA_HUMAN	Nicastrin	10993067	Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing.

P21127	CD11B_HUMAN	Cell division protein kinase 11B	12624090	The C-terminal kinase domain of the p34cdc2-related PITSLRE protein kinase (p110C) associates with p21-activated kinase 1 and inhibits its activity during anoikis.

P85059	ES1SA_RANSV	Esculentin-1SEa	16386333	Histamine-releasing and antimicrobial peptides from the skin secretions of the dusky gopher frog, Rana sevosa.

Q39152	FACR1_ARATH	Fatty acyl-CoA reductase 1	19062129	Functional expression of five Arabidopsis fatty acyl-CoA reductase genes in Escherichia coli.

Q91ZU9	NMD3B_MOUSE	Glutamate [NMDA] receptor subunit 3B	14602821	Specific assembly with the NMDA receptor 3B subunit controls surface expression and calcium permeability of NMDA receptors.

P46367	ALDH4_YEAST	Potassium-activated aldehyde dehydrogenase, mitochondrial	11502169	Yeast mitochondrial dehydrogenases are associated in a supramolecular complex.

Q12157	APC11_YEAST	Anaphase-promoting complex subunit 11	9469814	Mass spectrometric analysis of the anaphase-promoting complex from yeast: identification of a subunit related to cullins.

Q05947	YL224_YEAST	F-box protein YLR224W	14747994	Functional interaction of 13 yeast SCF complexes with a set of yeast E2 enzymes in vitro.

Q8R191	SNG3_MOUSE	Synaptogyrin-3	19357284	Physical and functional interaction between the dopamine transporter and the synaptic vesicle protein synaptogyrin-3.

P32485	HOG1_YEAST	Mitogen-activated protein kinase HOG1	12743037	Osmostress-induced transcription by Hot1 depends on a Hog1-mediated recruitment of the RNA Pol II.

Q29983	MICA_HUMAN	MHC class I polypeptide-related sequence A	10359807	Broad tumor-associated expression and recognition by tumor-derived gamma delta T cells of MICA and MICB.

Q12452	ERG27_YEAST	3-keto-steroid reductase	10535978	Characterization of the Saccharomyces cerevisiae ERG27 gene encoding the 3-keto reductase involved in C-4 sterol demethylation.

Q9QZX8	SO1B2_RAT	Solute carrier organic anion transporter family member 1B2	10838093	Identification of organic anion transporting polypeptide 4 (Oatp4) as a major full-length isoform of the liver-specific transporter-1 (rlst- 1) in rat liver.

Q9VVD9	S35B3_DROME	Adenosine 3'-phospho 5'-phosphosulfate transporter 2	16873373	Identification and characterization of a novel Drosophila 3'- phosphoadenosine 5'-phosphosulfate transporter.

P0AEU7	SKP_ECOLI	Chaperone protein skp	10455120	Skp, a molecular chaperone of Gram-negative bacteria, is required for the formation of soluble periplasmic intermediates of outer membrane proteins.

Q09JY9	SHRM2_XENTR	Protein Shroom2	16987870	Shroom2 (APXL) regulates melanosome biogenesis and localization in the retinal pigment epithelium.

O60566	BUB1B_HUMAN	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta	10477750	Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC.

Q9U518	ASPG_DIRIM	L-asparaginase	10579432	Identification of an asparagine amidohydrolase from the filarial parasite Dirofilaria immitis.

P14242	PMS1_YEAST	DNA mismatch repair protein PMS1	10938116	Functional studies on the candidate ATPase domains of Saccharomyces cerevisiae MutLalpha.

B1AQ75	KRT36_MOUSE	Keratin, type I cuticular Ha6	1385239	Structural features and sites of expression of a new murine 65 kD and 48 kD hair-related keratin pair, associated with a special type of parakeratotic epithelial differentiation.

P17544	ATF7_HUMAN	Cyclic AMP-dependent transcription factor ATF-7	15735663	A functional interaction between ATF7 and TAF12 that is modulated by TAF4.

O57460	TLL1_DANRE	Dorsal-ventral patterning tolloid-like protein 1	10375503	The role of tolloid/mini fin in dorsoventral pattern formation of the zebrafish embryo.

O74734	RRF1_SCHPO	Putative ribosomal recycling factor, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O88508	DNM3A_MOUSE	DNA (cytosine-5)-methyltransferase 3A	15215868	Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting.

P21743	IBP1_RAT	Insulin-like growth factor-binding protein 1	1705004	The gene encoding rat insulin-like growth factor-binding protein 1 is rapidly and highly induced in regenerating liver.

Q9NPA1	KCMB3_HUMAN	Calcium-activated potassium channel subunit beta-3	10692449	Cloning and functional characterization of novel large conductance calcium-activated potassium channel beta subunits, hKCNMB3 and hKCNMB4.

O13525	COQ4_YEAST	Ubiquinone biosynthesis protein COQ4, mitochondrial	11469793	Yeast COQ4 encodes a mitochondrial protein required for coenzyme Q synthesis.

P03372	ESR1_HUMAN	Estrogen receptor	17347654	CUE domain containing 2 regulates degradation of progesterone receptor by ubiquitin-proteasome.

P81058	PEN3A_LITVA	Penaeidin-3a	9353298	Penaeidins, a new family of antimicrobial peptides isolated from the shrimp Penaeus vannamei (Decapoda).

P23352	KALM_HUMAN	Anosmin-1	8832397	Initial characterization of anosmin-1, a putative extracellular matrix protein synthesized by definite neuronal cell populations in the central nervous system.

P38342	TSC10_YEAST	3-ketodihydrosphingosine reductase TSC10	14562095	Global analysis of protein localization in budding yeast.

Q99188	RGS2_YEAST	Regulator of G-protein signaling 2	10523302	A novel regulator of G protein signalling in yeast, Rgs2, downregulates glucose-activation of the cAMP pathway through direct inhibition of Gpa2.

O75478	TAD2A_HUMAN	Transcriptional adapter 2-alpha	9674425	Histone-like TAFs within the PCAF histone acetylase complex.

P30801	S10A6_RABIT	Protein S100-A6	9497364	Regulation of calcyclin (S100A6) binding by alternative splicing in the N-terminal regulatory domain of annexin XI isoforms.

Q9UTA6	YL8C_SCHPO	Uncharacterized hydrolase C25B8.12c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P13693	TCTP_HUMAN	Translationally-controlled tumor protein	15162379	Translationally controlled tumor protein (TCTP) in the human prostate and prostate cancer cells: expression, distribution, and calcium binding activity.

O94474	SKI3_SCHPO	Superkiller protein 3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O60182	RFC1_SCHPO	Replication factor C subunit 1	9891039	Fission yeast cdc24 is a replication factor C- and proliferating cell nuclear antigen-interacting factor essential for S-phase completion.

P38300	MBA1_YEAST	Protein MBA1, mitochondrial	8690083	MBA1 encodes a mitochondrial membrane-associated protein required for biogenesis of the respiratory chain.

Q13490	BIRC2_HUMAN	Baculoviral IAP repeat-containing protein 2	8548810	The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins.

Q9H0C8	ILKAP_HUMAN	Integrin-linked kinase-associated serine/threonine phosphatase 2C	11331582	Modulation of integrin signal transduction by ILKAP, a protein phosphatase 2C associating with the integrin-linked kinase, ILK1.

Q9UIQ6	LCAP_HUMAN	Leucyl-cystinyl aminopeptidase	8550619	Human placental leucine aminopeptidase/oxytocinase. A new member of type II membrane-spanning zinc metallopeptidase family.

P67444	XANQ_ECOLI	Xanthine permease XanQ	16096267	Cloning and functional characterization of two bacterial members of the NAT/NCS2 family in Escherichia coli.

P33519	RAN_DICDI	GTP-binding nuclear protein Ran	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

Q9DE09	HMX1_CHICK	Homeobox protein HMX1	11060230	Two homeobox genes define the domain of EphA3 expression in the developing chick retina.

Q9LE82	RAGP1_ARATH	RAN GTPase-activating protein 1	12061901	Plant RanGAPs are localized at the nuclear envelope in interphase and associated with microtubules in mitotic cells.

Q27884	PPP6_DROME	Serine/threonine-protein phosphatase 6 catalytic subunit	8223492	Drosophila protein phosphatase V functionally complements a SIT4 mutant in Saccharomyces cerevisiae and its amino-terminal region can confer this complementation to a heterologous phosphatase catalytic domain.

Q5BA61	PELB_EMENI	Pectin lyase B	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

Q8TDY2	RBCC1_HUMAN	RB1-inducible coiled-coil protein 1	19211835	Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy.

P53255	DRN1_YEAST	CWF19-like protein DRN1	14562095	Global analysis of protein localization in budding yeast.

P48561	TRF5_YEAST	Poly(A) RNA polymerase protein 1	16374505	Yeast Trf5p is a nuclear poly(A) polymerase.

O14788	TNF11_HUMAN	Tumor necrosis factor ligand superfamily member 11	9312132	TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells.

Q9HAV7	GRPE1_HUMAN	GrpE protein homolog 1, mitochondrial	11311562	Identification and characterization of a human mitochondrial homologue of the bacterial co-chaperone GrpE.

P06244	KAPA_YEAST	cAMP-dependent protein kinase type 1	3036373	Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase.

Q8VEM1	GOLI_MOUSE	E3 ubiquitin-protein ligase RNF130	10806348	Cloning of murine G1RP, a novel gene related to Drosophila melanogaster g1.

P76407	YEGS_ECOLI	Lipid kinase yegS	17351295	Crystal structure of yegS, a homologue to the mammalian diacylglycerol kinases, reveals a novel regulatory metal binding site.

Q9S7I6	RPK2_ARATH	LRR receptor-like serine/threonine-protein kinase RPK2	17419837	Receptor-like protein kinase 2 (RPK 2) is a novel factor controlling anther development in Arabidopsis thaliana.

P40933	IL15_HUMAN	Interleukin-15	8178155	Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor.

Q9Z2C8	YBOX2_MOUSE	Y-box-binding protein 2	11566752	Expression of MSY2 in mouse oocytes and preimplantation embryos.

P17275	JUNB_HUMAN	Transcription factor jun-B	2513129	jun-B inhibits and c-fos stimulates the transforming and trans- activating activities of c-jun.

Q9BUB4	ADAT1_HUMAN	tRNA-specific adenosine deaminase 1	10430867	Identification and characterization of a human tRNA-specific adenosine deaminase related to the ADAR family of pre-mRNA editing enzymes.

O75306	NDUS2_HUMAN	NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial	9647766	cDNA sequence and chromosomal localization of the remaining three human nuclear encoded iron sulphur protein (IP) subunits of complex I: the human IP fraction is completed.

Q9V938	OB57E_DROME	General odorant-binding protein 57e	12213773	Genome-wide analysis of the odorant-binding protein gene family in Drosophila melanogaster.

Q18825	BAR1_CAEEL	Beta-catenin/armadillo-related protein 1	15820693	LIN-23-mediated degradation of beta-catenin regulates the abundance of GLR-1 glutamate receptors in the ventral nerve cord of C. elegans.

P53937	SWS2_YEAST	37S ribosomal protein SWS2, mitochondrial	10649453	Analysis of deletion phenotypes and GFP fusions of 21 novel Saccharomyces cerevisiae open reading frames.

Q04637	IF4G1_HUMAN	Eukaryotic translation initiation factor 4 gamma 1	9857202	A newly identified N-terminal amino acid sequence of human eIF4G binds poly(A)-binding protein and functions in poly(A)-dependent translation.

Q9P7H0	NHP2_SCHPO	H/ACA ribonucleoprotein complex subunit 2	10502409	Functional conservation and cell cycle localization of the Nhp2 core component of H+ACA snoRNPs in fission and budding yeasts.

Q54F07	METK_DICDI	S-adenosylmethionine synthase	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q9C9L0	CUL3B_ARATH	Cullin-3B	15659098	Molecular and functional characterization of Arabidopsis Cullin 3A.

Q9M1D3	CISY5_ARATH	Citrate synthase 5, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P32613	TCA17_YEAST	TRAPP-associated protein TCA17	19220810	Identification of the novel TRAPP associated protein Tca17.

P13686	PPA5_HUMAN	Tartrate-resistant acid phosphatase type 5	2775236	Purification and characterization of a tartrate-resistant acid phosphatase from human osteoclastomas.

O44326	HMP2_CAEEL	Protein humpback-2	10952315	Distinct beta-catenins mediate adhesion and signalling functions in C. elegans.

P83546	CHY2_PAGMA	Chrysophsin-2	12581207	Purification and characterization of three isoforms of chrysophsin, a novel antimicrobial peptide in the gills of the red sea bream, Chrysophrys major.

P11831	SRF_HUMAN	Serum response factor	16054032	Phenotypic modulation of smooth muscle cells through interaction of Foxo4 and myocardin.

O17695	HDA1_CAEEL	Histone deacetylase 1	15990876	Chromatin regulation and sumoylation in the inhibition of Ras-induced vulval development in Caenorhabditis elegans.

P41338	THIL_YEAST	Acetyl-CoA acetyltransferase	7989303	ERG10 from Saccharomyces cerevisiae encodes acetoacetyl-CoA thiolase.

P19491	GRIA2_RAT	Glutamate receptor 2	10027300	Clustering of AMPA receptors by the synaptic PDZ domain-containing protein PICK1.

Q9MA55	ACBP4_ARATH	Acyl-CoA-binding domain-containing protein 4	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

P70354	MSX3_MOUSE	Homeobox protein MSX-3	11115394	Msx3 protein recruits histone deacetylase to down-regulate the Msx1 promoter.

Q6XNP7	HPI_HEVBR	Protease inhibitor HPI	16438995	Isolation and characterization of isoinhibitors of the potato protease inhibitor I family from the latex of the rubber trees, Hevea brasiliensis.

P00558	PGK1_HUMAN	Phosphoglycerate kinase 1	7391028	A single amino acid substitution (Asp leads to Asn) in a phosphoglycerate kinase variant (PGK Munchen) associated with enzyme deficiency.

Q6XAT2	ERL2_ARATH	LRR receptor-like serine/threonine-protein kinase ERL2	16002616	Stomatal patterning and differentiation by synergistic interactions of receptor kinases.

Q07327	ROP_DROME	Protein ROP	7917291	Mutations in the Drosophila Rop gene suggest a function in general secretion and synaptic transmission.

P42128	FOXK1_MOUSE	Forkhead box protein K1	10620510	The winged-helix/forkhead protein myocyte nuclear factor beta (MNF- beta) forms a co-repressor complex with mammalian Sin3B.

P31151	S10A7_HUMAN	Protein S100-A7	1940442	Molecular cloning, occurrence, and expression of a novel partially secreted protein 'psoriasin' that is highly up-regulated in psoriatic skin.

P78367	NKX32_HUMAN	Homeobox protein Nkx-3.2	9344671	Sequence and chromosomal assignment of human BAPX1, a bagpipe-related gene, to 4p16.1: a candidate gene for skeletal dysplasia.

P23570	IRF1_RAT	Interferon regulatory factor 1	2342469	Interferon-regulatory factor 1 is an immediate-early gene under transcriptional regulation by prolactin in Nb2 T cells.

Q874R4	YHS4_SCHPO	Putative cell agglutination protein C947.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q99177	BRR1_YEAST	Pre-mRNA-splicing factor BRR1	8861964	Transcriptional pulse-chase analysis reveals a role for a novel snRNP-associated protein in the manufacture of spliceosomal snRNPs.

P43603	LSB3_YEAST	LAS seventeen-binding protein 3	14562095	Global analysis of protein localization in budding yeast.

Q38868	CDPK9_ARATH	Calcium-dependent protein kinase 9	12068094	Calcium signaling through protein kinases. The Arabidopsis calcium- dependent protein kinase gene family.

Q8AVN9	ZN346_XENLA	Zinc finger protein 346	9268652	A Xenopus zinc finger protein that specifically binds dsRNA and RNA- DNA hybrids.

P33401	PGM1_YEAST	Phosphoglucomutase-1	8119301	A family of hexosephosphate mutases in Saccharomyces cerevisiae.

Q10953	WRM1_CAEEL	Armadillo repeat-containing protein wrm-1	11560894	The divergent Caenorhabditis elegans beta-catenin proteins BAR-1, WRM-1 and HMP-2 make distinct protein interactions but retain functional redundancy in vivo.

P25367	RNQ1_YEAST	[PIN+] prion protein RNQ1	11511345	Prions affect the appearance of other prions: the story of [PIN(+)].

Q9VKJ3	NU160_DROME	Nuclear pore complex protein Nup160 homolog	19197064	Evolution of the Drosophila nuclear pore complex results in multiple hybrid incompatibilities.

A8E0R9	GRIP2_XENLA	Glutamate receptor-interacting protein 2	17936745	XGRIP2.1 is encoded by a vegetally localizing, maternal mRNA and functions in germ cell development and anteroposterior PGC positioning in Xenopus laevis.

O00910	STATA_DICDI	Signal transducer and activator of transcription A	10393118	Evidence that the Dictyostelium Dd-STATa protein is a repressor that regulates commitment to stalk cell differentiation and is also required for efficient chemotaxis.

Q06134	SPO77_YEAST	Sporulation-specific protein 77	11470404	A screen for genes required for meiosis and spore formation based on whole-genome expression.

Q9UKK3	PARP4_HUMAN	Poly [ADP-ribose] polymerase 4	10477748	The 193 kDa vault protein, VPARP, is a novel poly(ADP-ribose) polymerase.

Q13769	THOC5_HUMAN	THO complex subunit 5 homolog	18974867	Recruitment of the complete hTREX complex is required for Kaposi's sarcoma-associated herpesvirus intronless mRNA nuclear export and virus replication.

Q99767	APBA2_HUMAN	Amyloid beta A4 precursor protein-binding family A member 2	9890987	Interaction of a neuron-specific protein containing PDZ domains with Alzheimer's amyloid precursor protein.

P25653	FIG2_YEAST	Factor-induced gene 2 protein	12455698	Maintenance of mating cell integrity requires the adhesin Fig2p.

Q7TNY1	BACD2_RAT	BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2	15726626	Cloning of two rat PDIP1 related genes and their interactions with proliferating cell nuclear antigen.

Q06137	YL345_YEAST	Putative 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase YLR345W	15494396	Identification of new genes regulated by the Crt1 transcription factor, an effector of the DNA damage checkpoint pathway in Saccharomyces cerevisiae.

O94628	YGE9_SCHPO	Uncharacterized methyltransferase C1347.09	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UQ07	MOK_HUMAN	MAPK/MAK/MRK overlapping kinase	10421840	Molecular cloning and characterization of a novel member of the MAP kinase superfamily.

Q05962	ADT1_RAT	ADP/ATP translocase 1	8399300	Isolation and characterization of cDNA clones and a genomic clone encoding rat mitochondrial adenine nucleotide translocator.

Q16518	RPE65_HUMAN	Retinoid isomerohydrolase	9326941	Mutations in RPE65 cause autosomal recessive childhood-onset severe retinal dystrophy.

P53168	DUO1_YEAST	DASH complex subunit DUO1	15640796	The yeast DASH complex forms closed rings on microtubules.

Q9Y265	RUVB1_HUMAN	RuvB-like 1	10966108	Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis.

Q9FRV0	CHIC_SECCE	Basic endochitinase C	11826968	Localization, accumulation, and antifungal activity of chitinases in rye (Secale cereale) seed.

P43082	HEVL_ARATH	Hevein-like protein	8118053	Regulation of a hevein-like gene in Arabidopsis.

P0AG63	RS17_ECOLI	30S ribosomal protein S17	4598121	Assembly mapping of 30 S ribosomal proteins from Escherichia coli. Further studies.

P82705	IM04_DROME	Immune-induced peptide 4	9736738	Differential display of peptides induced during the immune response of Drosophila: a matrix-assisted laser desorption ionization time-of- flight mass spectrometry study.

Q91YE5	BAZ2A_MOUSE	Bromodomain adjacent to zinc finger domain protein 2A	12198165	The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription.

Q02685	RMI1_YEAST	RecQ-mediated genome instability protein 1	14562095	Global analysis of protein localization in budding yeast.

Q8MKK4	TRE12_DROME	Facilitated trehalose transporter Tret1-2 homolog	20035867	The trehalose transporter 1 gene sequence is conserved in insects and encodes proteins with different kinetic properties involved in trehalose import into peripheral tissues.

P18088	DCE1_RAT	Glutamate decarboxylase 1	1924335	Cloning, characterization, and autoimmune recognition of rat islet glutamic acid decarboxylase in insulin-dependent diabetes mellitus.

P22855	MAN1_YEAST	Alpha-mannosidase	2266133	A novel pathway of import of alpha-mannosidase, a marker enzyme of vacuolar membrane, in Saccharomyces cerevisiae.

P25847	MSH2_YEAST	DNA mismatch repair protein MSH2	8805366	Binding of insertion/deletion DNA mismatches by the heterodimer of yeast mismatch repair proteins MSH2 and MSH3.

P84140	G6PI_THELI	Glucose-6-phosphate isomerase	12560104	Characterization of the cupin-type phosphoglucose isomerase from the hyperthermophilic archaeon Thermococcus litoralis.

Q94517	HDAC1_DROME	Histone deacetylase Rpd3	15545624	Identification of a Drosophila Myb-E2F2/RBF transcriptional repressor complex.

Q12959	DLG1_HUMAN	Disks large homolog 1	12766944	Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer.

P70033	NR6A1_XENLA	Nuclear receptor subfamily 6 group A member 1	10452854	A role for xGCNF in midbrain-hindbrain patterning in Xenopus laevis.

Q05955	ADY4_YEAST	Accumulates dyads protein 4	12796288	Ady4p and Spo74p are components of the meiotic spindle pole body that promote growth of the prospore membrane in Saccharomyces cerevisiae.

P04805	SYE_ECOLI	Glutamyl-tRNA synthetase	8218204	The glutamyl-tRNA synthetase of Escherichia coli contains one atom of zinc essential for its native conformation and its catalytic activity.

Q64604	PTPRF_RAT	Receptor-type tyrosine-protein phosphatase F	1918076	Cloning, bacterial expression, purification, and characterization of the cytoplasmic domain of rat LAR, a receptor-like protein tyrosine phosphatase.

Q8CIS9	K1C9_RAT	Keratin, type I cytoskeletal 9	11071770	Keratin 9 is a component of the perinuclear ring of the manchette of rat spermatids.

P87239	MDJ1_SCHPO	DnaJ homolog 1, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q93VD3	CIPKN_ARATH	CBL-interacting serine/threonine-protein kinase 23	17922773	Two calcineurin B-like calcium sensors, interacting with protein kinase CIPK23, regulate leaf transpiration and root potassium uptake in Arabidopsis.

Q8GWJ4	OSB3_ARATH	Protein OSB3, chloroplastic/mitochondrial	17189341	The plant-specific ssDNA binding protein OSB1 is involved in the stoichiometric transmission of mitochondrial DNA in Arabidopsis.

Q12464	RUVB2_YEAST	RuvB-like protein 2	15045029	A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin.

Q9Y651	SOX21_HUMAN	Transcription factor SOX-21	1614875	A conserved family of genes related to the testis determining gene, SRY.

O16850	FOXO_CAEEL	Forkhead box protein O	17096597	p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans.

Q8LAH8	NDK4_ARATH	Nucleoside diphosphate kinase IV, chloroplastic/mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P40481	MNI1_YEAST	Mitotic exit network interactor 1	14562095	Global analysis of protein localization in budding yeast.

P87215	DIMI_SCHPO	Mitosis protein dim1	9182666	Fission yeast dim1(+) encodes a functionally conserved polypeptide essential for mitosis.

Q9FX31	HDG11_ARATH	Homeobox-leucine zipper protein HDG11	16778018	Characterization of the class IV homeodomain-leucine zipper gene family in Arabidopsis.

Q9UJX6	ANC2_HUMAN	Anaphase-promoting complex subunit 2	9469815	Identification of a cullin homology region in a subunit of the anaphase-promoting complex.

Q9BYM8	UB7I3_HUMAN	RanBP-type and C3HC4-type zinc finger-containing protein 1	17006537	A ubiquitin ligase complex assembles linear polyubiquitin chains.

A1Z9E2	LIN54_DROME	Protein lin-54 homolog	15479636	Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes.

P21827	RCC1_YEAST	Regulator of chromosome condensation	2548085	Yeast pheromone response pathway: characterization of a suppressor that restores mating to receptorless mutants.

Q9Y6D9	MD1L1_HUMAN	Mitotic spindle assembly checkpoint protein MAD1	9546394	Human T cell leukemia virus type 1 oncoprotein Tax targets the human mitotic checkpoint protein MAD1.

O95210	STBD1_HUMAN	Starch-binding domain-containing protein 1	9794794	Molecular cloning and functional expression of a novel human gene encoding two 41-43 kDa skeletal muscle internal membrane proteins.

Q03862	ARX1_YEAST	Probable metalloprotease ARX1	16648468	Nuclear recycling of the pre-60S ribosomal subunit-associated factor Arx1 depends on Rei1 in Saccharomyces cerevisiae.

P32460	DCG1_YEAST	Protein DCG1	1916277	Sequences of two adjacent genes, one (DAL2) encoding allantoicase and another (DCG1) sensitive to nitrogen-catabolite repression in Saccharomyces cerevisiae.

P50150	GBG4_HUMAN	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4	7665596	Isolation of cDNA clones encoding eight different human G protein gamma subunits, including three novel forms designated the gamma 4, gamma 10, and gamma 11 subunits.

Q9US38	YFZ3_SCHPO	AB hydrolase superfamily protein C1039.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P62838	UB2D2_MOUSE	Ubiquitin-conjugating enzyme E2 D2	17576800	Regulation of synaptic growth and maturation by a synapse-associated E3 ubiquitin ligase at the neuromuscular junction.

Q96RN5	MED15_HUMAN	Mediator of RNA polymerase II transcription subunit 15	18568018	TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal.

Q33DR3	DLP1_MOUSE	Decaprenyl-diphosphate synthase subunit 2	16262699	Characterization of solanesyl and decaprenyl diphosphate synthases in mice and humans.

P40302	PSA1_YEAST	Proteasome component PRE5	9087403	Structure of 20S proteasome from yeast at 2.4-A resolution.

Q550R2	CTXB_DICDI	Cortexillin-2	8752217	Cortexillins, major determinants of cell shape and size, are actin- bundling proteins with a parallel coiled-coil tail.

Q05937	STP3_YEAST	Zinc finger protein STP3	14562095	Global analysis of protein localization in budding yeast.

O42601	S17B1_XENLA	Transcription factor Sox-17-beta.1	16278889	Genomic profiling of mixer and Sox17beta targets during Xenopus endoderm development.

Q8L735	ISOA2_ARATH	Isoamylase 2, chloroplastic	18815382	Further evidence for the mandatory nature of polysaccharide debranching for the aggregation of semicrystalline starch and for overlapping functions of debranching enzymes in Arabidopsis leaves.

Q12372	MMP1_YEAST	S-methylmethionine permease 1	10497160	Transport of sulfonium compounds. Characterization of the s- adenosylmethionine and s-methylmethionine permeases from the yeast Saccharomyces cerevisiae.

Q96N67	DOCK7_HUMAN	Dedicator of cytokinesis protein 7	16982419	The Rac activator DOCK7 regulates neuronal polarity through local phosphorylation of stathmin/Op18.

Q8NFF5	FAD1_HUMAN	FAD synthase	16643857	Over-expression in Escherichia coli and characterization of two recombinant isoforms of human FAD synthetase.

P20107	ZRC1_YEAST	Zinc/cadmium resistance protein	2693940	Identification of a gene conferring resistance to zinc and cadmium ions in the yeast Saccharomyces cerevisiae.

P49913	CAMP_HUMAN	Cathelicidin antimicrobial peptide	8681941	The human gene FALL39 and processing of the cathelin precursor to the antibacterial peptide LL-37 in granulocytes.

Q03103	ERO1_YEAST	Endoplasmic oxidoreductin-1	9659913	The ERO1 gene of yeast is required for oxidation of protein dithiols in the endoplasmic reticulum.

Q23498	ASM2_CAEEL	Sphingomyelin phosphodiesterase 2	9603947	Caenorhabditis elegans contains two distinct acid sphingomyelinases.

Q9ERR7	SEP15_MOUSE	15 kDa selenoprotein	11278576	Association between the 15-kDa selenoprotein and UDP- glucose:glycoprotein glucosyltransferase in the endoplasmic reticulum of mammalian cells.

P61163	ACTZ_HUMAN	Alpha-centractin	1528266	A vertebrate actin-related protein is a component of a multisubunit complex involved in microtubule-based vesicle motility.

Q20646	CEP1_CAEEL	Transcription factor cep-1	17347667	The nucleotide excision repair pathway is required for UV-C-induced apoptosis in Caenorhabditis elegans.

O43000	LIZ1_SCHPO	Pantothenate transporter liz1	15075270	Cell division defects of Schizosaccharomyces pombe liz1- mutants are caused by defects in pantothenate uptake.

Q9BXI3	5NT1A_HUMAN	Cytosolic 5'-nucleotidase 1A	11133996	Human cytosolic 5'-nucleotidase I: characterization and role in nucleoside analog resistance.

O15552	FFAR2_HUMAN	Free fatty acid receptor 2	12496283	The orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.

Q02630	NU116_YEAST	Nucleoporin NUP116/NSP116	8524308	Yeast nucleoporin mutants are defective in pre-tRNA splicing.

P47167	MCM22_YEAST	Central kinetochore subunit MCM22	11782448	Ctf3p, the Mis6 budding yeast homolog, interacts with Mcm22p and Mcm16p at the yeast outer kinetochore.

P25044	PTP1_YEAST	Tyrosine-protein phosphatase 1	1649172	Cloning and expression of a yeast protein tyrosine phosphatase.

P63058	THA_MOUSE	Thyroid hormone receptor alpha	16322094	Characterization of a novel thyroid hormone receptor alpha variant involved in the regulation of myoblast differentiation.

P49028	MGN_DROME	Protein mago nashi	9210377	The mago nashi gene is required for the polarisation of the oocyte and the formation of perpendicular axes in Drosophila.

O35263	PA1B3_RAT	Platelet-activating factor acetylhydrolase IB subunit gamma	9459487	Molecular cloning of cDNAs encoding alpha1, alpha2, and beta subunits of rat brain platelet-activating factor acetylhydrolase.

Q8H1Z0	WAX2_ARATH	Protein WAX2	12724542	Cloning and characterization of the WAX2 gene of Arabidopsis involved in cuticle membrane and wax production.

O18211	MO25M_CAEEL	MO25-like protein 2	17676955	Dynein modifiers in C. elegans: light chains suppress conditional heavy chain mutants.

Q2LAE1	ASHH2_ARATH	Histone-lysine N-methyltransferase ASHH2	10518493	The early-flowering mutant efs is involved in the autonomous promotion pathway of Arabidopsis thaliana.

P40925	MDHC_HUMAN	Malate dehydrogenase, cytoplasmic	8786100	Molecular cloning and mapping of a human cDNA for cytosolic malate dehydrogenase (MDH1).

P32266	MGM1_YEAST	Dynamin-like GTPase MGM1, mitochondrial	12566426	The intramitochondrial dynamin-related GTPase, Mgm1p, is a component of a protein complex that mediates mitochondrial fusion.

Q38868	CDPK9_ARATH	Calcium-dependent protein kinase 9	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q9T074	PCKA_ARATH	Phosphoenolpyruvate carboxykinase [ATP]	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

P08081	CLCA_RAT	Clathrin light chain A	3563513	Clathrin light chains LCA and LCB are similar, polymorphic, and share repeated heptad motifs.

P28584	TRK2_YEAST	Low-affinity potassium transport protein	2072919	TRK1 and TRK2 encode structurally related K+ transporters in Saccharomyces cerevisiae.

Q5VST9	OBSCN_HUMAN	Obscurin	12527750	Binding of an ankyrin-1 isoform to obscurin suggests a molecular link between the sarcoplasmic reticulum and myofibrils in striated muscles.

P13378	HXD8_HUMAN	Homeobox protein Hox-D8	2568311	Complementary homeo protein gradients in developing limb buds.

O55099	AURKB_RAT	Serine/threonine-protein kinase 12	9450992	AIM-1: a mammalian midbody-associated protein required for cytokinesis.

P04637	P53_HUMAN	Cellular tumor antigen p53	8875929	Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain.

Q70DU8	AL3H1_ARATH	Aldehyde dehydrogenase family 3 member H1	15830124	Detailed expression analysis of selected genes of the aldehyde dehydrogenase(ALDH) gene superfamily in Arabidopsis thaliana.

Q9LYU8	AK1_ARATH	Aspartokinase 1, chloroplastic	9207839	Molecular characterisation of an Arabidopsis thaliana cDNA coding for a monofunctional aspartate kinase.

O59827	GST2_SCHPO	Glutathione S-transferase 2	11997110	A second stress-inducible glutathione S-transferase gene from Schizosaccharomyces pombe.

P63224	GMHA_ECOLI	Phosphoheptose isomerase	8631969	Biosynthesis of inner core lipopolysaccharide in enteric bacteria identification and characterization of a conserved phosphoheptose isomerase.

O60072	MUG81_SCHPO	Putative helicase mug81	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9FKV1	ANTR5_ARATH	Probable anion transporter 5	18086223	Functional analysis of the Arabidopsis PHT4 family of intracellular phosphate transporters.

Q9CQJ4	RING2_MOUSE	E3 ubiquitin-protein ligase RING2	10369680	RYBP, a new repressor protein that interacts with components of the mammalian Polycomb complex, and with the transcription factor YY1.

P35869	AHR_HUMAN	Aryl hydrocarbon receptor	7961644	Dioxin binding activities of polymorphic forms of mouse and human arylhydrocarbon receptors.

Q9C9H5	GUN9_ARATH	Endoglucanase 9	9188482	Differential extraction and protein sequencing reveals major differences in patterns of primary cell wall proteins from plants.

Q8BSL7	ARF2_MOUSE	ADP-ribosylation factor 2	8947846	Structure and intracellular localization of mouse ADP-ribosylation factors type 1 to type 6 (ARF1-ARF6).

O94488	MBO1_SCHPO	Microtubule organizer protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P22301	IL10_HUMAN	Interleukin-10	11485736	Crystal structure of the IL-10/IL-10R1 complex reveals a shared receptor binding site.

P38633	MED31_YEAST	Mediator of RNA polymerase II transcription subunit 31	14562095	Global analysis of protein localization in budding yeast.

Q9ESN4	C1QL3_MOUSE	Complement C1q-like protein 3	10862616	Conformational requirements of collagenous peptides for recognition by the chaperone protein HSP47.

O50202	ARC_RHOER	Proteasome-associated ATPase	9514743	Characterization of ARC, a divergent member of the AAA ATPase family from Rhodococcus erythropolis.

Q16512	PKN1_HUMAN	Serine/threonine-protein kinase N1	18066052	Phosphorylation of histone H3 at threonine 11 establishes a novel chromatin mark for transcriptional regulation.

P51610	HCFC1_HUMAN	Host cell factor 1	19815555	The deubiquitinating enzyme BAP1 regulates cell growth via interaction with HCF-1.

Q07959	IZH3_YEAST	ADIPOR-like receptor IZH3	15060275	Metalloregulation of yeast membrane steroid receptor homologs.

P23409	MYF6_HUMAN	Myogenic factor 6	2311584	Myf-6, a new member of the human gene family of myogenic determination factors: evidence for a gene cluster on chromosome 12.

O33246	PUP_MYCTU	Prokaryotic ubiquitin-like protein Pup	20203624	The mycobacterial Mpa-proteasome unfolds and degrades pupylated substrates by engaging Pup's N-terminus.

P15923	TFE2_HUMAN	Transcription factor E2-alpha	9409784	The mUBC9 murine ubiquitin conjugating enzyme interacts with the E2A transcription factors.

Q9MA55	ACBP4_ARATH	Acyl-CoA-binding domain-containing protein 4	18836139	Ethylene- and pathogen-inducible Arabidopsis acyl-CoA-binding protein 4 interacts with an ethylene-responsive element binding protein.

Q9VZW5	FMAR_DROME	FMRFamide receptor	12218185	Molecular cloning and functional expression of the first insect FMRFamide receptor.

Q8WV28	BLNK_HUMAN	B-cell linker protein	9697839	BLNK: a central linker protein in B cell activation.

P38571	LICH_HUMAN	Lysosomal acid lipase/cholesteryl ester hydrolase	1718995	Cloning and expression of cDNA encoding human lysosomal acid lipase/cholesteryl ester hydrolase. Similarities to gastric and lingual lipases.

O75143	ATG13_HUMAN	Autophagy-related protein 13	19597335	Atg101, a novel mammalian autophagy protein interacting with Atg13.

Q944H2	AB12I_ARATH	Protein ABCI12, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

P10081	IF4A_YEAST	ATP-dependent RNA helicase eIF4A	10480875	Interaction of translation initiation factor eIF4G with eIF4A in the yeast Saccharomyces cerevisiae.

Q91620	NOD2A_XENLA	Nodal homolog 2-A	15530392	Visualizing long-range movement of the morphogen Xnr2 in the Xenopus embryo.

Q9HC77	CENPJ_HUMAN	Centromere protein J	11003675	Protein 4.1 R-135 interacts with a novel centrosomal protein (CPAP) which is associated with the gamma-tubulin complex.

Q86UE4	LYRIC_HUMAN	Protein LYRIC	18440304	LYRIC/AEG-1 overexpression modulates BCCIPalpha protein levels in prostate tumor cells.

P47072	YJB6_YEAST	Uncharacterized protein YJL016W/YJL017W	14562095	Global analysis of protein localization in budding yeast.

Q8T1C6	GNT1_DICDI	[Skp1-protein]-hydroxyproline N-acetylglucosaminyltransferase	12244115	Molecular cloning and expression of a UDP-N-acetylglucosamine (GlcNAc):hydroxyproline polypeptide GlcNAc-transferase that modifies Skp1 in the cytoplasm of Dictyostelium.

P60720	LIPB_ECOLI	Octanoyltransferase	15642479	Expression, purification, and physical characterization of Escherichia coli lipoyl(octanoyl)transferase.

P77338	KEFA_ECOLI	Potassium efflux system KefA	10202137	Protection of Escherichia coli cells against extreme turgor by activation of MscS and MscL mechanosensitive channels: identification of genes required for MscS activity.

O94248	MDN1_SCHPO	Midasin	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P55212	CASP6_HUMAN	Caspase-6	7796396	Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene family.

Q9UUI3	SA145_SCHPO	Spliceosome-associated protein 145	11884590	Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

O43602	DCX_HUMAN	Neuronal migration protein doublecortin	9489699	A novel CNS gene required for neuronal migration and involved in X- linked subcortical laminar heterotopia and lissencephaly syndrome.

Q9GZZ9	UBA5_HUMAN	Ubiquitin-like modifier-activating enzyme 5	15071506	A novel protein-conjugating system for Ufm1, a ubiquitin-fold modifier.

Q9D132	UPK1A_MOUSE	Uroplakin-1a	11739641	Uroplakin Ia is the urothelial receptor for uropathogenic Escherichia coli: evidence from in vitro FimH binding.

Q9AGG3	RUBY_PORGI	Rubrerythrin	11972784	Role of rubrerythrin in the oxidative stress response of Porphyromonas gingivalis.

Q8H1U5	APC2_ARATH	Anaphase-promoting complex subunit 2	17944809	Specialization of CDC27 function in the Arabidopsis thaliana anaphase-promoting complex (APC/C).

Q9P793	MIT1_SCHPO	Chromatin remodeling factor mit1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O14064	BIR1_SCHPO	Protein bir1	11554922	Bir1/Cut17 moving from chromosome to spindle upon the loss of cohesion is required for condensation, spindle elongation and repair.

Q9URV1	PLG7_SCHPO	Putative phospholipase A2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P01834	IGKC_HUMAN	Ig kappa chain C region	5489770	The covalent structure of a human gamma G-immunoglobulin. VI. Amino acid sequence of the light chain.

P07271	PIF1_YEAST	DNA repair and recombination protein PIF1	10926538	Pif1p helicase, a catalytic inhibitor of telomerase in yeast.

Q39024	MPK4_ARATH	Mitogen-activated protein kinase 4	15358537	Involvement of MPK4 in osmotic stress response pathways in cell suspensions and plantlets of Arabidopsis thaliana: activation by hypoosmolarity and negative role in hyperosmolarity tolerance.

O60259	KLK8_HUMAN	Kallikrein-8	19194479	SPINK9: a selective, skin-specific Kazal-type serine protease inhibitor.

Q9UKT4	FBX5_HUMAN	F-box only protein 5	16439210	The evi5 oncogene regulates cyclin accumulation by stabilizing the anaphase-promoting complex inhibitor emi1.

O75443	TECTA_HUMAN	Alpha-tectorin	9590290	Mutations in the human alpha-tectorin gene cause autosomal dominant non-syndromic hearing impairment.

Q96C10	DHX58_HUMAN	Probable ATP-dependent RNA helicase DHX58	19278996	The RIG-I-like receptor LGP2 recognizes the termini of double- stranded RNA.

P19836	PCY1A_RAT	Choline-phosphate cytidylyltransferase A	2166941	Cloning and expression of rat liver CTP:phosphocholine cytidylyltransferase: an amphipathic protein that controls phosphatidylcholine synthesis.

P86147	PROTO_ORADR	Venom peptide 2-long	18695936	Novel mastoparan and protonectin analogs isolated from a solitary wasp, Orancistrocerus drewseni drewseni.

Q3TDX8	NB5R4_MOUSE	Cytochrome b5 reductase 4	15247412	Absence of a reductase, NCB5OR, causes insulin-deficient diabetes.

Q63584	TMEDA_RAT	Transmembrane emp24 domain-containing protein 10	8663407	Tmp21 and p24A, two type I proteins enriched in pancreatic microsomal membranes, are members of a protein family involved in vesicular trafficking.

Q9R1M5	NALP5_MOUSE	NACHT, LRR and PYD domains-containing protein 5	10433232	A mouse gene encoding an oocyte antigen associated with autoimmune premature ovarian failure.

O95274	LYPD3_HUMAN	Ly6/PLAUR domain-containing protein 3	15012588	Structural analysis and tissue localization of human C4.4A: a protein homologue of the urokinase receptor.

P63272	SPT4H_HUMAN	Transcription elongation factor SPT4	8786137	Isolation and characterization of the human and mouse homologues (SUPT4H and Supt4h) of the yeast SPT4 gene.

Q9V496	APLP_DROME	Apolipophorins	8702812	Molecular characterization and developmental expression of a retinoid- and fatty acid-binding glycoprotein from Drosophila: a putative lipophorin.

O43345	ZN208_HUMAN	Zinc finger protein 208	9724325	Complex beta-satellite repeat structures and the expansion of the zinc finger gene cluster in 19p12.

Q9Z1J1	TF7L1_MOUSE	Transcription factor 7-like 1	10498690	Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation.

Q8IWX8	CHERP_HUMAN	Calcium homeostasis endoplasmic reticulum protein	10794731	Cloning of human Ca2+ homoeostasis endoplasmic reticulum protein (CHERP): regulated expression of antisense cDNA depletes CHERP, inhibits intracellular Ca2+ mobilization and decreases cell proliferation.

Q6XQ84	PTEG_XENLA	Proximal tubules-expressed gene protein	19909807	XPteg (Xenopus proximal tubules-expressed gene) is essential for pronephric mesoderm specification and tubulogenesis.

P33767	OSTB_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1	9405463	The highly conserved Stt3 protein is a subunit of the yeast oligosaccharyltransferase and forms a subcomplex with Ost3p and Ost4p.

Q08650	DGA1_YEAST	Diacylglycerol O-acyltransferase 1	11751830	Synthesis of triacylglycerols by the acyl-coenzyme A:diacyl-glycerol acyltransferase Dga1p in lipid particles of the yeast Saccharomyces cerevisiae.

Q9USR6	NAT9_SCHPO	N-acetyltransferase 9-like protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P10909	CLUS_HUMAN	Clusterin	2387851	Purification and characterization of apolipoprotein J.

P36526	RM27_YEAST	54S ribosomal protein L27, mitochondrial	12392552	Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components.

Q03691	ROT1_YEAST	Protein ROT1	9545237	Cell wall integrity modulates RHO1 activity via the exchange factor ROM2.

Q24119	TRH_DROME	Protein trachealess	11740943	Regulation of Drosophila tracheal system development by protein kinase B.

P51840	GUC2E_RAT	Guanylyl cyclase GC-E	7831337	Two membrane forms of guanylyl cyclase found in the eye.

P98177	FOXO4_HUMAN	Forkhead box protein O4	12761217	The forkhead transcription factor FOXO4 induces the down-regulation of hypoxia-inducible factor 1 alpha by a von Hippel-Lindau protein- independent mechanism.

O35814	STIP1_RAT	Stress-induced-phosphoprotein 1	9528774	The carboxy-terminal domain of Hsc70 provides binding sites for a distinct set of chaperone cofactors.

O14196	MU165_SCHPO	Meiotically up-regulated gene 165 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P0ACC3	ERPA_ECOLI	Iron-sulfur cluster insertion protein erpA	17698959	ErpA, an iron sulfur (Fe S) protein of the A-type essential for respiratory metabolism in Escherichia coli.

Q10407	MKH1_SCHPO	MAP kinase kinase kinase mkh1	9199286	Mkh1, a MEK kinase required for cell wall integrity and proper response to osmotic and temperature stress in Schizosaccharomyces pombe.

P48240	MTR3_YEAST	Exosome complex component MTR3	10465791	The yeast exosome and human PM-Scl are related complexes of 3'-->5' exonucleases.

O74796	ORC6_SCHPO	Origin recognition complex subunit 6	10535928	Identification and reconstitution of the origin recognition complex from Schizosaccharomyces pombe.

Q9HC77	CENPJ_HUMAN	Centromere protein J	11984006	The Chediak-Higashi protein interacts with SNARE complex and signal transduction proteins.

Q9P3W1	T2EA_SCHPO	Transcription initiation factor IIE subunit alpha	15743411	Studies of Schizosaccharomyces pombe TFIIE indicate conformational and functional changes in RNA polymerase II at transcription initiation.

P83876	TXN4A_HUMAN	Thioredoxin-like protein 4A	10610776	Identification, characterization and crystal structure analysis of the human spliceosomal U5 snRNP-specific 15kD protein.

Q9Y2G3	AT11B_HUMAN	Probable phospholipid-transporting ATPase IF	11790799	Reanalysis of ATP11B, a Type IV P-type ATPase.

P84810	LVP1A_BUTOC	Lipolysis-activating peptide 1-alpha chain	15680238	Isolation and molecular characterization of LVP1 lipolysis activating peptide from scorpion Buthus occitanus tunetanus.

Q8NFW9	MYRIP_HUMAN	Rab effector MyRIP	11964381	MyRIP, a novel Rab effector, enables myosin VIIa recruitment to retinal melanosomes.

P41227	NAA10_HUMAN	N-alpha-acetyltransferase 10, NatA catalytic subunit	15496142	Identification and characterization of the human ARD1-NATH protein acetyltransferase complex.

P55862	MCM5A_XENLA	DNA replication licensing factor mcm5-A	9851868	Evidence for different MCM subcomplexes with differential binding to chromatin in Xenopus.

Q99613	EIF3C_HUMAN	Eukaryotic translation initiation factor 3 subunit C	17322308	Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry.

Q07205	IF5_RAT	Eukaryotic translation initiation factor 5	8464924	Molecular cloning and expression of cDNA for mammalian translation initiation factor 5.

P57752	ACBP6_ARATH	Acyl-CoA-binding domain-containing protein 6	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P41823	SY65_APLCA	Synaptotagmin-1	7479985	Evidence for synaptotagmin as an inhibitory clamp on synaptic vesicle release in Aplysia neurons.

P56163	DPF1_RAT	Zinc finger protein neuro-d4	1454523	Differential splicing creates a diversity of transcripts from a neurospecific developmentally regulated gene encoding a protein with new zinc-finger motifs.

Q00141	NCPR_ASPNG	NADPH--cytochrome P450 reductase	7646819	Cloning and characterization of the NADPH cytochrome P450 oxidoreductase gene from the filamentous fungus Aspergillus niger.

P38876	PTH_YEAST	Peptidyl-tRNA hydrolase	14562095	Global analysis of protein localization in budding yeast.

P0AEG6	DSBC_ECOLI	Thiol:disulfide interchange protein DsbC	19965429	A periplasmic reducing system protects single cysteine residues from oxidation.

P62068	UBP46_HUMAN	Ubiquitin carboxyl-terminal hydrolase 46	19075014	UAF1 is a subunit of multiple deubiquitinating enzyme complexes.

P20236	GBRA3_RAT	Gamma-aminobutyric acid receptor subunit alpha-3	2153588	Functional expression and sites of gene transcription of a novel alpha subunit of the GABAA receptor in rat brain.

P38862	ATG7_YEAST	Ubiquitin-like modifier-activating enzyme ATG7	11100732	A ubiquitin-like system mediates protein lipidation.

Q93Y06	Y5720_ARATH	Probable inactive receptor kinase At5g67200	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

P07713	DECA_DROME	Protein decapentaplegic	3123323	The decapentaplegic gene is required for dorsal-ventral patterning of the Drosophila embryo.

Q12959	DLG1_HUMAN	Disks large homolog 1	9192623	Binding of human virus oncoproteins to hDlg/SAP97, a mammalian homolog of the Drosophila discs large tumor suppressor protein.

Q8R448	OTOSP_MOUSE	Otospiralin	11880501	Down regulation of otospiralin, a novel inner ear protein, causes hair cell degeneration and deafness.

P40073	SSU81_YEAST	Protein SSU81	7624781	Activation of yeast PBS2 MAPKK by MAPKKKs or by binding of an SH3- containing osmosensor.

O42601	S17B1_XENLA	Transcription factor Sox-17-beta.1	9363948	Xsox17alpha and -beta mediate endoderm formation in Xenopus.

Q12380	ATG5_YEAST	Autophagy protein 5	11897782	Formation of the approximately 350-kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast.

Q9GT24	ZYG1_CAEEL	Probable serine/threonine-protein kinase zyg-1	15665853	SAS-6 defines a protein family required for centrosome duplication in C. elegans and in human cells.

Q9NS82	AAA1_HUMAN	Asc-type amino acid transporter 1	10863037	Cloning and characterization of a human brain Na+-independent transporter for small neutral amino acids that transports D-serine with high affinity.

P53202	CUL3_YEAST	Cullin-3	17296727	ELA1 and CUL3 are required along with ELC1 for RNA polymerase II polyubiquitylation and degradation in DNA-damaged yeast cells.

P43605	ECO1_YEAST	N-acetyltransferase ECO1	12665596	Mechanical link between cohesion establishment and DNA replication: Ctf7p/Eco1p, a cohesion establishment factor, associates with three different replication factor C complexes.

Q8NE79	POPD1_HUMAN	Blood vessel epicardial substance	10441744	Cloning and expression of hbves, a novel and highly conserved mRNA expressed in the developing and adult heart and skeletal muscle in the human.

P24530	EDNRB_HUMAN	Endothelin B receptor	8810293	Molecular characterization of a novel human endothelin receptor splice variant.

Q6P1M3	L2GL2_HUMAN	Lethal(2) giant larvae protein homolog 2	15632202	Direct binding of Lgl2 to LGN during mitosis and its requirement for normal cell division.

Q96LI5	CNO6L_HUMAN	CCR4-NOT transcription complex subunit 6-like	17452450	Depletion of mammalian CCR4b deadenylase triggers elevation of the p27Kip1 mRNA level and impairs cell growth.

P05156	CFAI_HUMAN	Complement factor I	2956252	Human complement factor I: analysis of cDNA-derived primary structure and assignment of its gene to chromosome 4.

Q12947	FOXF2_HUMAN	Forkhead box protein F2	8626802	Differential activation of lung-specific genes by two forkhead proteins, FREAC-1 and FREAC-2.

Q708S6	ACC2C_DANRE	Amiloride-sensitive cation channel 2-C, neuronal	14970195	A family of acid-sensing ion channels (ASICs) from the zebrafish: widespread e xpression in the central nervous system suggests a conserved role in neuronal communication.

Q6IRB2	HES1A_XENLA	Transcription factor HES-1-A	17008450	Characterization and function of the bHLH-O protein XHes2: insight into the mechanisms controlling retinal cell fate decision.

P51557	STAR_MOUSE	Steroidogenic acute regulatory protein, mitochondrial	7961770	The purification, cloning, and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR).

Q9VCR6	SAV_DROME	Scaffold protein salvador	12202036	Salvador promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines.

P35914	HMGCL_HUMAN	Hydroxymethylglutaryl-CoA lyase, mitochondrial	16330550	Crystal structure of human 3-hydroxy-3-methylglutaryl-CoA Lyase: insights into catalysis and the molecular basis for hydroxymethylglutaric aciduria.

Q12830	BPTF_HUMAN	Nucleosome-remodeling factor subunit BPTF	10575013	Fetal Alz-50 clone 1, a novel zinc finger protein, binds a specific DNA sequence and acts as a transcriptional regulator.

P34243	HCS1_YEAST	DNA polymerase alpha-associated DNA helicase A	8257676	DNA helicase associated with DNA polymerase alpha: isolation by a modified immunoaffinity chromatography.

Q8WY21	SORC1_HUMAN	VPS10 domain-containing receptor SorCS1	12482870	Characterization of sorCS1, an alternatively spliced receptor with completely different cytoplasmic domains that mediate different trafficking in cells.

P52306	GDS1_HUMAN	Rap1 GTPase-GDP dissociation stimulator 1	1549351	Molecular cloning of the human cDNA for a stimulatory GDP/GTP exchange protein for c-Ki-ras p21 and smg p21.

Q9JLZ8	SIGIR_MOUSE	Single Ig IL-1-related receptor	12925853	SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling.

P38719	DBP8_YEAST	ATP-dependent RNA helicase DBP8	16772403	The nucleolar protein Esf2 interacts directly with the DExD/H box RNA helicase, Dbp8, to stimulate ATP hydrolysis.

Q924U1	KISSR_RAT	KiSS-1 receptor	11457843	The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54.

Q86Y39	NDUAB_HUMAN	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

P50336	PPOX_HUMAN	Protoporphyrinogen oxidase	7713909	Cloning of a human cDNA for protoporphyrinogen oxidase by complementation in vivo of a hemG mutant of Escherichia coli.

Q8GUL8	UGPI1_ARATH	Uncharacterized GPI-anchored protein At5g19230	12805588	Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis.

P29674	LHX1_XENLA	LIM/homeobox protein Lhx1	7990959	Role of the LIM class homeodomain protein Xlim-1 in neural and muscle induction by the Spemann organizer in Xenopus.

P25189	MYP0_HUMAN	Myelin protein P0	7693130	Deletion of the serine 34 codon from the major peripheral myelin protein P0 gene in Charcot-Marie-Tooth disease type 1B.

Q13503	MED21_HUMAN	Mediator of RNA polymerase II transcription subunit 21	8598913	A mammalian SRB protein associated with an RNA polymerase II holoenzyme.

O60346	PHLP1_HUMAN	PH domain leucine-rich repeat-containing protein phosphatase 1	15808505	PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth.

P36165	TGL4_YEAST	Lipase 4	14562095	Global analysis of protein localization in budding yeast.

Q9Z0J8	NEGR1_RAT	Neuronal growth regulator 1	10075727	Characterization of a novel rat brain glycosylphosphatidylinositol- anchored protein (Kilon), a member of the IgLON cell adhesion molecule family.

Q96WV9	CDK9_SCHPO	Serine/threonine-protein kinase cdk9	16428435	Cyclin-dependent kinase 9 (Cdk9) of fission yeast is activated by the CDK-activating kinase Csk1, overlaps functionally with the TFIIH- associated kinase Mcs6, and associates with the mRNA cap methyltransferase Pcm1 in vivo.

Q9UGM3	DMBT1_HUMAN	Deleted in malignant brain tumors 1 protein	9288095	DMBT1, a new member of the SRCR superfamily on chromosome 10q25.3- q26.1 is deleted in malignant brain tumours.

Q14190	SIM2_HUMAN	Single-minded homolog 2	8661114	The mammalian single-minded (SIM) gene: mouse cDNA structure and diencephalic expression indicate a candidate gene for Down syndrome.

P61587	RND3_HUMAN	Rho-related GTP-binding protein RhoE	9531558	A new member of the Rho family, Rnd1, promotes disassembly of actin filament structures and loss of cell adhesion.

O15244	S22A2_HUMAN	Solute carrier family 22 member 2	9260930	Cloning and characterization of two human polyspecific organic cation transporters.

Q09500	CTNS_CAEEL	Cystinosin homolog	18351800	Phagocytic receptor CED-1 initiates a signaling pathway for degrading engulfed apoptotic cells.

Q8VBT9	ASPC1_MOUSE	Tether containing UBX domain for GLUT4	14562105	Functional cloning of TUG as a regulator of GLUT4 glucose transporter trafficking.

Q39253	CAX1_ARATH	Vacuolar cation/proton exchanger 1	10559438	Expression of Arabidopsis CAX1 in tobacco: altered calcium homeostasis and increased stress sensitivity.

Q24537	HMG2_DROME	High mobility group protein DSP1	8072548	An HMG-like protein that can switch a transcriptional activator to a repressor.

P06761	GRP78_RAT	78 kDa glucose-regulated protein	3087629	An Hsp70-like protein in the ER: identity with the 78 kd glucose- regulated protein and immunoglobulin heavy chain binding protein.

O43464	HTRA2_HUMAN	Serine protease HTRA2, mitochondrial	10995577	Tissue-specific splicing of Omi stress-regulated endoprotease leads to an inactive protease with a modified PDZ motif.

O94334	POF13_SCHPO	F-box protein pof13	15147268	Molecular interactions of fission yeast Skp1 and its role in the DNA damage checkpoint.

P40957	MAD1_YEAST	Spindle assembly checkpoint component MAD1	10436016	The spindle checkpoint of budding yeast depends on a tight complex between the Mad1 and Mad2 proteins.

P53724	RM50_YEAST	54S ribosomal protein L50, mitochondrial	12392552	Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components.

P21128	ENDOU_HUMAN	Poly(U)-specific endoribonuclease	2350438	Cloning and expression of a cDNA encoding human placental protein 11, a putative serine protease with diagnostic significance as a tumor marker.

P14678	RSMB_HUMAN	Small nuclear ribonucleoprotein-associated proteins B and B'	12975319	Unique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processing.

P46681	DLD2_YEAST	D-lactate dehydrogenase [cytochrome] 2, mitochondrial	15158445	Interaction of D-lactate dehydrogenase protein 2 (Dld2p) with F- actin: implication for an alternative function of Dld2p.

A0MES8	ABI4_ARATH	Ethylene-responsive transcription factor ABI4	10950871	Analysis of Arabidopsis glucose insensitive mutants, gin5 and gin6, reveals a central role of the plant hormone ABA in the regulation of plant vegetative development by sugar.

Q84MC7	PYL9_ARATH	Abscisic acid receptor PYL9	19874541	PYR/PYL/RCAR family members are major in-vivo ABI1 protein phosphatase 2C-interacting proteins in Arabidopsis.

P47045	TIM54_YEAST	Mitochondrial import inner membrane translocase subunit TIM54	12637749	Protein insertion into the mitochondrial inner membrane by a twin- pore translocase.

P41800	MMM1_YEAST	Maintenance of mitochondrial morphology protein 1	16407407	Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins.

O60832	DKC1_HUMAN	H/ACA ribonucleoprotein complex subunit 4	16601202	hNaf1 is required for accumulation of human box H/ACA snoRNPs, scaRNPs, and telomerase.

Q9P377	BGS3_SCHPO	1,3-beta-glucan synthase component bgs3	12582133	Bgs3p, a putative 1,3-beta-glucan synthase subunit, is required for cell wall assembly in Schizosaccharomyces pombe.

Q38826	IAA8_ARATH	Auxin-responsive protein IAA8	12036262	Genetics of Aux/IAA and ARF action in plant growth and development.

P49893	WN11B_XENLA	Protein Wnt-11b	11128985	Xwnt11 and the regulation of gastrulation in Xenopus.

Q43315	FPPS2_ARATH	Farnesyl pyrophosphate synthase 2	8631820	Arabidopsis thaliana contains two differentially expressed farnesyl- diphosphate synthase genes.

Q9FH76	ABAH3_ARATH	Abscisic acid 8'-hydroxylase 3	17010113	Regulation of hormone metabolism in Arabidopsis seeds: phytochrome regulation of abscisic acid metabolism and abscisic acid regulation of gibberellin metabolism.

P49893	WN11B_XENLA	Protein Wnt-11b	18715946	GATA transcription factors integrate Wnt signalling during heart development.

P25345	SYNM_YEAST	Asparaginyl-tRNA synthetase, mitochondrial	9030748	Mitochondrial asparaginyl-tRNA synthetase is encoded by the yeast nuclear gene YCR24c.

P11349	NARH_ECOLI	Respiratory nitrate reductase 1 beta chain	3053688	Roles of the narJ and narI gene products in the expression of nitrate reductase in Escherichia coli.

Q9JIP7	S15A1_MOUSE	Solute carrier family 15 member 1	11004485	cDNA structure, genomic organization, and promoter analysis of the mouse intestinal peptide transporter PEPT1.

P38242	ALG14_YEAST	UDP-N-acetylglucosamine transferase subunit ALG14	17686769	Membrane topology of the Alg14 endoplasmic reticulum UDP-GlcNAc transferase subunit.

Q99999	G3ST1_HUMAN	Galactosylceramide sulfotransferase	9030544	Molecular cloning and expression of cDNA encoding human 3'- phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase.

O88396	GRPE2_MOUSE	GrpE protein homolog 2, mitochondrial	9694873	Evidence for the existence of distinct mammalian cytosolic, microsomal, and two mitochondrial GrpE-like proteins, the co- chaperones of specific Hsp70 members.

Q15517	CDSN_HUMAN	Corneodesmosin	8415725	Identification in the HLA class I region of a gene expressed late in keratinocyte differentiation.

Q6AYD6	PDLI2_RAT	PDZ and LIM domain protein 2	15505042	Pdlim2, a novel PDZ-LIM domain protein, interacts with alpha-actinins and filamin A.

Q9JKP5	MBNL1_MOUSE	Muscleblind-like protein 1	10970838	Recruitment of human muscleblind proteins to (CUG)(n) expansions associated with myotonic dystrophy.

P52739	ZN131_HUMAN	Zinc finger protein 131	7557990	Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders.

P06576	ATPB_HUMAN	ATP synthase subunit beta, mitochondrial	2687158	The human ATP synthase beta subunit gene: sequence analysis, chromosome assignment, and differential expression.

O22137	PP202_ARATH	Pentatricopeptide repeat-containing protein At2g45350, chloroplastic	15662426	A pentatricopeptide repeat protein is essential for RNA editing in chloroplasts.

Q66WV0	RBR1_NICBE	Retinoblastoma-related protein 1	15807779	Retinoblastoma protein regulates cell proliferation, differentiation, and endoreduplication in plants.

Q9HCC9	LST2_HUMAN	Lateral signaling target protein 2 homolog	19460345	Monoubiquitinylation regulates endosomal localization of Lst2, a negative regulator of EGF receptor signaling.

Q13620	CUL4B_HUMAN	Cullin-4B	12609982	TIP120A associates with cullins and modulates ubiquitin ligase activity.

Q99929	ASCL2_HUMAN	Achaete-scute homolog 2	11440538	The human Achaete Scute homolog 2 gene contains two promotors, generating overlapping transcripts and encoding two proteins with different nuclear localization.

Q9JHW9	AL1A3_MOUSE	Aldehyde dehydrogenase family 1 member A3	11044606	Identification of RALDH-3, a novel retinaldehyde dehydrogenase, expressed in the ventral region of the retina.

O16299	FIGL1_CAEEL	Fidgetin-like protein 1	15581640	Identification of a cysteine residue important for the ATPase activity of C. elegans fidgetin homologue.

P08649	CO4_RAT	Complement C4	8805663	Complement C4 protein expression by rat hepatic stellate cells.

P31384	CCR4_YEAST	Glucose-repressible alcohol dehydrogenase transcriptional effector	10490603	The CCR4 and CAF1 proteins of the CCR4-NOT complex are physically and functionally separated from NOT2, NOT4, and NOT5.

O81055	ASK16_ARATH	SKP1-like protein 16	14749489	Expression and interaction analysis of Arabidopsis Skp1-related genes.

O15397	IPO8_HUMAN	Importin-8	9214382	A novel class of RanGTP binding proteins.

O49354	COQ3_ARATH	Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial	9628017	Cloning and functional expression of AtCOQ3, the Arabidopsis homologue of the yeast COQ3 gene, encoding a methyltransferase from plant mitochondria involved in ubiquinone biosynthesis.

Q8N370	LAT4_HUMAN	Large neutral amino acids transporter small subunit 4	15659399	Identification of LAT4, a novel amino acid transporter with system L activity.

Q9VW15	ASH1_DROME	Histone-lysine N-methyltransferase ash1	12397363	Histone methylation by the Drosophila epigenetic transcriptional regulator Ash1.

P52872	DAD1_CAEEL	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit dad-1	7556086	dad-1, an endogenous programmed cell death suppressor in Caenorhabditis elegans and vertebrates.

P53955	SLM2_YEAST	Phosphatidylinositol 4,5-bisphosphate-binding protein SLM2	15689497	The pleckstrin homology domain proteins Slm1 and Slm2 are required for actin cytoskeleton organization in yeast and bind phosphatidylinositol-4,5-bisphosphate and TORC2.

Q9P7K3	YJN2_SCHPO	Uncharacterized kinase C24B10.02c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q10339	EXO70_SCHPO	Exocyst complex component exo70	11854409	The multiprotein exocyst complex is essential for cell separation in Schizosaccharomyces pombe.

P80362	KV125_HUMAN	Ig kappa chain V-I region WAT	7993911	Comparison of crystal structures of two homologous proteins: structural origin of altered domain interactions in immunoglobulin light-chain dimers.

P83253	DISA_VIPLE	Disintegrin lebein-1-alpha	11343790	Amino acid structure and characterization of a heterodimeric disintegrin from Vipera lebetina venom.

Q14254	FLOT2_HUMAN	Flotillin-2	8051082	Cloning and characterization of a novel epidermal cell surface antigen (ESA).

P0CE00	MPH3_YEAST	Alpha-glucosides permease MPH3	12210897	Characterization of the putative maltose transporters encoded by YDL247w and YJR160c.

O42923	CIP1_SCHPO	RNA-binding post-transcriptional regulator cip1	16407405	Cip1 and Cip2 are novel RNA-recognition-motif proteins that counteract Csx1 function during oxidative stress.

P26885	FKBP2_HUMAN	Peptidyl-prolyl cis-trans isomerase FKBP2	1713687	Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13.

P92208	JNK_DROME	Stress-activated protein kinase JNK	8946915	A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila.

Q03897	YD128_YEAST	WD repeat-containing protein YDR128W	14562095	Global analysis of protein localization in budding yeast.

P34087	RPB7_YEAST	DNA-directed RNA polymerase II subunit RPB7	11087726	Dissociable Rpb4-Rpb7 subassembly of RNA polymerase II binds to single-strand nucleic acid and mediates a post-recruitment step in transcription initiation.

O14832	PAHX_HUMAN	Phytanoyl-CoA dioxygenase, peroxisomal	9326940	Refsum disease is caused by mutations in the phytanoyl-CoA hydroxylase gene.

P18507	GBRG2_HUMAN	Gamma-aminobutyric acid receptor subunit gamma-2	9892355	GABA(A)-receptor-associated protein links GABA(A) receptors and the cytoskeleton.

Q9QZE3	CATQ_RAT	Cathepsin Q	10673370	Cathepsin Q, a novel lysosomal cysteine protease highly expressed in placenta.

P0ABZ6	SURA_ECOLI	Chaperone surA	8985185	SurA, a periplasmic protein with peptidyl-prolyl isomerase activity, participates in the assembly of outer membrane porins.

Q9NZL6	RGL1_HUMAN	Ral guanine nucleotide dissociation stimulator-like 1	10760592	The human RGL (RalGDS-like) gene: cloning, expression analysis and genomic organization.

P49000	MIS_RAT	Muellerian-inhibiting factor	1572639	Isolation of the rat gene for Mullerian inhibiting substance.

P38876	PTH_YEAST	Peptidyl-tRNA hydrolase	12475929	Orthologs of a novel archaeal and of the bacterial peptidyl-tRNA hydrolase are nonessential in yeast.

O44406	ERI1_CAEEL	3'-5' exonuclease eri-1	14961122	A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans.

Q94JM3	ARFB_ARATH	Auxin response factor 2	16339187	The AUXIN RESPONSE FACTOR 2 gene of Arabidopsis links auxin signalling, cell division, and the size of seeds and other organs.

P49626	RL4B_YEAST	60S ribosomal protein L4-B	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q96WW4	YNI7_SCHPO	Uncharacterized protein C11B10.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12891	HYAL2_HUMAN	Hyaluronidase-2	9712871	HYAL2, a human gene expressed in many cells, encodes a lysosomal hyaluronidase with a novel type of specificity.

Q16661	GUC2B_HUMAN	Guanylate cyclase activator 2B	8605041	Cloning and characterization of a cDNA encoding a precursor for human uroguanylin.

P0C8P4	KYNB_RALME	Kynurenine formamidase	14592712	Aerobic tryptophan degradation pathway in bacteria: novel kynurenine formamidase.

P49815	TSC2_HUMAN	Tuberin	9580671	Interaction between hamartin and tuberin, the TSC1 and TSC2 gene products.

P53667	LIMK1_HUMAN	LIM domain kinase 1	10436159	Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase.

Q5XM24	APRA_DICDI	Autocrine proliferation repressor protein A	18611962	The secreted Dictyostelium protein CfaD is a chalone.

P40366	DLS1_YEAST	Protein DLS1	14673157	Noncompetitive counteractions of DNA polymerase epsilon and ISW2/yCHRAC for epigenetic inheritance of telomere position effect in Saccharomyces cerevisiae.

Q9NZ72	STMN3_HUMAN	Stathmin-3	9603203	SCLIP: a novel SCG10-like protein of the stathmin family expressed in the nervous system.

P28791	SEC20_YEAST	Protein transport protein SEC20	12853481	Use1p is a yeast SNARE protein required for retrograde traffic to the ER.

B7ZS96	TTHY_XENLA	Transthyretin	11080066	Evolution of structure, ontogeny of gene expression, and function of Xenopus laevis transthyretin.

Q9Y2H6	FND3A_HUMAN	Fibronectin type-III domain-containing protein 3A	18218838	HUGO (FNDC3A): a new gene overexpressed in human odontoblasts.

Q9C9W9	ADO3_ARATH	Adagio protein 3	14749489	Expression and interaction analysis of Arabidopsis Skp1-related genes.

Q9FK72	HFA4C_ARATH	Heat stress transcription factor A-4c	18381353	A new mutant of Arabidopsis disturbed in its roots, right-handed slanting, and gravitropism defines a gene that encodes a heat-shock factor.

Q99523	SORT_HUMAN	Sortilin	11331584	The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein.

O15111	IKKA_HUMAN	Inhibitor of nuclear factor kappa-B kinase subunit alpha	11971985	Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) coactivator activity by I kappa B kinase.

P38909	CYC2_YEAST	Cytochrome c mitochondrial import factor CYC2	14562095	Global analysis of protein localization in budding yeast.

Q8NFH4	NUP37_HUMAN	Nucleoporin Nup37	17363900	The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions.

Q9WU34	SEPT3_RAT	Neuronal-specific septin-3	15485489	Septin 3 (G-septin) is a developmentally regulated phosphoprotein enriched in presynaptic nerve terminals.

Q61644	PACN1_MOUSE	Protein kinase C and casein kinase substrate in neurons protein 1	11082044	All three PACSIN isoforms bind to endocytic proteins and inhibit endocytosis.

Q03833	GIS1_YEAST	Transcriptional activator/repressor GIS1	10835355	Saccharomyces cerevisiae Ras/cAMP pathway controls post-diauxic shift element-dependent transcription through the zinc finger protein Gis1.

Q9W3C7	PPT1_DROME	Palmitoyl-protein thioesterase 1	12909364	Characterization of Drosophila palmitoyl-protein thioesterase 1.

P70331	MDFI_MOUSE	MyoD family inhibitor	9799236	Requirement of the mouse I-mfa gene for placental development and skeletal patterning.

P48450	ERG7_RAT	Lanosterol synthase	16440058	Lanosterol synthase mutations cause cholesterol deficiency-associated cataracts in the Shumiya cataract rat.

Q9C895	BRE1B_ARATH	E3 ubiquitin-protein ligase BRE1-like 2	17329565	The Arabidopsis thaliana homolog of yeast BRE1 has a function in cell cycle regulation during early leaf and root growth.

Q9Y6R0	NUMBL_HUMAN	Numb-like protein	20079715	NUMBL interacts with TRAF6 and promotes the degradation of TRAF6.

Q9NGX9	CP302_DROME	Cytochrome P450 302a1, mitochondrial	12676319	Regulation of glial cell number and differentiation by ecdysone and Fos signaling.

Q9BUN8	DERL1_HUMAN	Derlin-1	16449189	Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation.

Q99741	CDC6_HUMAN	Cell division control protein 6 homolog	8990175	A human protein related to yeast Cdc6p.

Q00916	RU17_YEAST	U1 small nuclear ribonucleoprotein 70 kDa homolog	9630245	A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins.

Q15545	TAF7_HUMAN	Transcription initiation factor TFIID subunit 7	15960975	Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

O60543	CIDEA_HUMAN	Cell death activator CIDE-A	9564035	CIDE, a novel family of cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factor.

P38152	TXTP_YEAST	Tricarboxylate transport protein	7876161	High level expression and characterization of the mitochondrial citrate transport protein from the yeast Saccharomyces cerevisiae.

Q62941	ZNT2_RAT	Zinc transporter 2	8617223	ZnT-2, a mammalian protein that confers resistance to zinc by facilitating vesicular sequestration.

Q13363	CTBP1_HUMAN	C-terminal-binding protein 1	8440238	A region in the C-terminus of adenovirus 2/5 E1a protein is required for association with a cellular phosphoprotein and important for the negative modulation of T24-ras mediated transformation, tumorigenesis and metastasis.

P23469	PTPRE_HUMAN	Receptor-type tyrosine-protein phosphatase epsilon	2170109	Structural diversity and evolution of human receptor-like protein tyrosine phosphatases.

Q3KQ35	S17AA_XENLA	Transcription factor Sox-17-alpha-A	15157240	Early endodermal expression of the Xenopus Endodermin gene is driven by regulatory sequences containing essential Sox protein-binding elements.

Q8LAH7	OPR1_ARATH	12-oxophytodienoate reductase 1	9346960	Molecular cloning and characterization of 12-oxophytodienoate reductase, an enzyme of the octadecanoid signaling pathway from Arabidopsis thaliana. Structural and functional relationship to yeast old yellow enzyme.

P53192	GET1_YEAST	Golgi to ER traffic protein 1	11907266	Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae.

Q9P797	NU131_SCHPO	Nucleoporin nup131	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q00972	BCKD_RAT	[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial	7649998	Expression and characterization of branched-chain alpha-ketoacid dehydrogenase kinase from the rat. Is it a histidine-protein kinase?

Q9GYS1	MES6_CAEEL	Polycomb protein mes-6	15380065	The MES-2/MES-3/MES-6 complex and regulation of histone H3 methylation in C. elegans.

P56945	BCAR1_HUMAN	Breast cancer anti-estrogen resistance protein 1	10587647	Melanoma chondroitin sulphate proteoglycan regulates cell spreading through Cdc42, Ack-1 and p130cas.

O42955	YGM7_SCHPO	Pentatricopeptide repeat-containing protein C19G7.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NPY3	C1QR1_HUMAN	Complement component C1q receptor	10092817	C1qRP is a heavily O-glycosylated cell surface protein involved in the regulation of phagocytic activity.

P55201	BRPF1_HUMAN	Peregrin	16387653	ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.

P47061	VPS53_YEAST	Vacuolar protein sorting-associated protein 53	11689439	An effector of Ypt6p binds the SNARE Tlg1p and mediates selective fusion of vesicles with late Golgi membranes.

Q5S007	LRRK2_HUMAN	Leucine-rich repeat serine/threonine-protein kinase 2	16352719	Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin and mutant LRRK2 induces neuronal degeneration.

Q9P0L9	PK2L1_HUMAN	Polycystic kidney disease 2-like 1 protein	10517637	Polycystin-L is a calcium-regulated cation channel permeable to calcium ions.

Q19468	MBOA7_CAEEL	Lysophospholipid acyltransferase 7	18094042	Caenorhabditis elegans mboa-7, a member of the MBOAT family, is required for selective incorporation of polyunsaturated fatty acids into phosphatidylinositol.

Q9NP71	WBS14_HUMAN	Williams-Beuren syndrome chromosomal region 14 protein	9860302	Complete physical map of the common deletion region in Williams syndrome and identification and characterization of three novel genes.

Q55DH8	CATB_DICDI	Catalase-B	11004503	Differential developmental expression and cell type specificity of Dictyostelium catalases and their response to oxidative stress and UV- light.

Q6PDU5	BEX3_RAT	Protein BEX3	10764727	NADE, a p75NTR-associated cell death executor, is involved in signal transduction mediated by the common neurotrophin receptor p75NTR.

P52644	HSLJ_ECOLI	Heat shock protein hslJ	8349564	Characterization of twenty-six new heat shock genes of Escherichia coli.

Q80Z64	NANOG_MOUSE	Homeobox protein NANOG	15582778	Pluripotential competence of cells associated with Nanog activity.

Q9BQB4	SOST_HUMAN	Sclerostin	11181578	Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST).

P52496	DNLI4_CANAL	DNA ligase 4	10487922	Cell cycle regulation of a DNA ligase-encoding gene (CaLIG4) from Candida albicans.

O43087	KMS2_SCHPO	Karyogamy meiotic segregation protein 2	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

Q15054	DPOD3_HUMAN	DNA polymerase delta subunit 3	10219083	Isolation and identification of the third subunit of mammalian DNA polymerase delta by PCNA-affinity chromatography of mouse FM3A cell extracts.

Q9V730	EXT1_DROME	Exostosin-1	15056609	Abrogation of heparan sulfate synthesis in Drosophila disrupts the Wingless, Hedgehog and Decapentaplegic signaling pathways.

Q96CW5	GCP3_HUMAN	Gamma-tubulin complex component 3	9566967	The mammalian gamma-tubulin complex contains homologues of the yeast spindle pole body components spc97p and spc98p.

Q09760	CUL3_SCHPO	Cullin-3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q08496	DIA2_YEAST	Protein DIA2	14747994	Functional interaction of 13 yeast SCF complexes with a set of yeast E2 enzymes in vitro.

Q9W1N6	GR59E_DROME	Putative gustatory receptor 59e	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

Q94BT2	AIR12_ARATH	Auxin-induced in root cultures protein 12	10080694	Isolation and characterization of cDNA clones corresponding with mRNAs that accumulate during auxin-induced lateral root formation.

Q99661	KIF2C_HUMAN	Kinesin-like protein KIF2C	19060894	Genome stability is ensured by temporal control of kinetochore- microtubule dynamics.

Q8R4L0	SLAP2_MOUSE	Src-like-adapter 2	12024036	Functional cooperation between c-Cbl and Src-like adaptor protein 2 in the negative regulation of T-cell receptor signaling.

P51805	PLXA3_HUMAN	Plexin-A3	8570614	A family of transmembrane proteins with homology to the MET- hepatocyte growth factor receptor.

P78552	I13R1_HUMAN	Interleukin-13 receptor subunit alpha-1	9013879	Cloning of the human IL-13R alpha1 chain and reconstitution with the IL4R alpha of a functional IL-4/IL-13 receptor complex.

Q7Z401	MYCPP_HUMAN	C-myc promoter-binding protein	8056341	Cloning of a cDNA encoding a human protein which binds a sequence in the c-myc gene similar to the interferon-stimulated response element.

O01836	GLH3_CAEEL	ATP-dependent RNA helicase glh-3	12435362	The GLH proteins, Caenorhabditis elegans P granule components, associate with CSN-5 and KGB-1, proteins necessary for fertility, and with ZYX-1, a predicted cytoskeletal protein.

P46639	KNAT1_ARATH	Homeobox protein knotted-1-like 1	17873098	The Arabidopsis BEL1-LIKE HOMEODOMAIN proteins SAW1 and SAW2 act redundantly to regulate KNOX expression spatially in leaf margins.

Q9Y5A7	NUB1_HUMAN	NEDD8 ultimate buster 1	14757770	NEDD8 ultimate buster-1L interacts with the ubiquitin-like protein FAT10 and accelerates its degradation.

O88480	CABIN_RAT	Calcineurin-binding protein cabin-1	9660798	Cain, a novel physiologic protein inhibitor of calcineurin.

Q99P86	RETNB_MOUSE	Resistin-like beta	11209052	A family of tissue-specific resistin-like molecules.

P17133	RU17_DROME	U1 small nuclear ribonucleoprotein 70 kDa	15990112	Structural basis of the interaction between P-element somatic inhibitor and U1-70k essential for the alternative splicing of P- element transposase.

P32366	VA0D_YEAST	V-type proton ATPase subunit d	8509410	The Saccharomyces cerevisiae VMA6 gene encodes the 36-kDa subunit of the vacuolar H(+)-ATPase membrane sector.

Q9V3P6	PSMD1_DROME	26S proteasome non-ATPase regulatory subunit 1	10893261	The regulatory complex of Drosophila melanogaster 26S proteasomes. Subunit composition and localization of a deubiquitylating enzyme.

P41000	CPS3_SCHPO	Protein cps3	7857672	Molecular cloning and characterization of a fission yeast gene responsible for supersensitivity to the spindle poison, isopropyl N-3- chlorophenyl carbamate.

Q9Y2C9	TLR6_HUMAN	Toll-like receptor 6	10231569	TLR6: a novel member of an expanding Toll-like receptor family.

Q9P202	WHRN_HUMAN	Whirlin	17171570	A novel gene for Usher syndrome type 2: mutations in the long isoform of whirlin are associated with retinitis pigmentosa and sensorineural hearing loss.

Q9UBR1	BUP1_HUMAN	Beta-ureidopropionase	10542323	cDNA cloning, genomic structure and chromosomal localization of the human BUP-1 gene encoding beta-ureidopropionase.

P42669	PURA_MOUSE	Transcriptional activator protein Pur-alpha	9334258	Sequence of cDNAs encoding components of vascular actin single- stranded DNA-binding factor 2 establish identity to Puralpha and Purbeta.

Q9M8S8	VTC4_ARATH	Inositol-phosphate phosphatase	15550539	A highly specific L-galactose-1-phosphate phosphatase on the path to ascorbate biosynthesis.

P12956	XRCC6_HUMAN	X-ray repair cross-complementing protein 6	15075319	Positive and negative modulation of the transcriptional activity of the ETS factor ESE-1 through interaction with p300, CREB-binding protein, and Ku 70/86.

O94436	TAF14_SCHPO	Transcription initiation factor TFIID subunit 14	15616156	Tfg3, a subunit of the general transcription factor TFIIF in Schizosaccharomyces pombe, functions under stress conditions.

P20051	PYRC_YEAST	Dihydroorotase	2897615	Structure of the Saccharomyces cerevisiae URA4 gene encoding dihydroorotase.

Q64559	BACH_RAT	Cytosolic acyl coenzyme A thioester hydrolase	9125130	Molecular cloning and expression of cDNAs encoding rat brain and liver cytosolic long-chain acyl-CoA hydrolases.

P47977	CTH2_YEAST	mRNA decay factor CTH2	14562095	Global analysis of protein localization in budding yeast.

O14333	PSD2_SCHPO	Phosphatidylserine decarboxylase proenzyme 2, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P78357	CNTP1_HUMAN	Contactin-associated protein 1	9118959	Identification of a novel contactin-associated transmembrane receptor with multiple domains implicated in protein-protein interactions.

P17079	RL12_YEAST	60S ribosomal protein L12	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

P08559	ODPA_HUMAN	Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial	3034892	The human pyruvate dehydrogenase complex. Isolation of cDNA clones for the E1 alpha subunit, sequence analysis, and characterization of the mRNA.

P24928	RPB1_HUMAN	DNA-directed RNA polymerase II subunit RPB1	18550522	Snapshots of the RNA processing factor SCAF8 bound to different phosphorylated forms of the carboxyl-terminal domain of RNA polymerase II.

Q05787	HRD3_YEAST	ERAD-associated E3 ubiquitin-protein ligase component HRD3	16873065	A luminal surveillance complex that selects misfolded glycoproteins for ER-associated degradation.

O43683	BUB1_HUMAN	Mitotic checkpoint serine/threonine-protein kinase BUB1	9790499	Human Bub1: a putative spindle checkpoint kinase closely linked to cell proliferation.

P83573	ARALB_ARAEL	Aralin B chain	12963119	Aralin, a new cytotoxic protein from Aralia elata, inducing apoptosis in human cancer cells.

P47013	DS1P1_YEAST	Dihydrosphingosine 1-phosphate phosphatase LCB3	10563329	Yeast sphingosine-1-phosphate phosphatases: assay, expression, deletion, purification, and cellular localization by GFP tagging.

Q08109	HRD1_YEAST	ERAD-associated E3 ubiquitin-protein ligase HRD1	11146622	Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER- associated degradation.

Q9XIC7	SERK2_ARATH	Somatic embryogenesis receptor kinase 2	16284305	The Arabidopsis thaliana SOMATIC EMBRYOGENESIS RECEPTOR-LIKE KINASES1 and 2 control male sporogenesis.

Q04418	RBA50_YEAST	RNA polymerase II-associated protein RBA50	14690591	Assigning function to yeast proteins by integration of technologies.

O43080	YHS3_SCHPO	Uncharacterized protein C947.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P18888	SNF6_YEAST	Transcription regulatory protein SNF6	2188093	SNF6 encodes a nuclear protein that is required for expression of many genes in Saccharomyces cerevisiae.

O77059	CRY1_DROME	Cryptochrome-1	18597555	Human and Drosophila cryptochromes are light activated by flavin photoreduction in living cells.

Q13237	KGP2_HUMAN	cGMP-dependent protein kinase 2	8607838	Molecular cloning, cDNA structure, and chromosomal localization of the human type II cGMP-dependent protein kinase.

Q90888	MAFB_CHICK	Transcription factor MafB	11036080	A set of Hox proteins interact with the Maf oncoprotein to inhibit its DNA binding, transactivation, and transforming activities.

Q15599	NHRF2_HUMAN	Na(+)/H(+) exchange regulatory cofactor NHE-RF2	19555689	MCC, a new interacting protein for Scrib, is required for cell migration in epithelial cells.

O94650	HUB1_SCHPO	Ubiquitin-like modifier hub1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8WTS1	ABHD5_HUMAN	1-acylglycerol-3-phosphate O-acyltransferase ABHD5	18606822	CGI-58, the causative gene for Chanarin-Dorfman syndrome, mediates acylation of lysophosphatidic acid.

O23006	LYM2_ARATH	LysM domain-containing GPI-anchored protein 2	12805588	Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis.

Q9XYF4	ICENC_DROME	Caspase Nc	12021771	The DIAP1 RING finger mediates ubiquitination of Dronc and is indispensable for regulating apoptosis.

O42606	NGN1_DANRE	Neurogenin-1	12015292	Delta/Notch signaling promotes formation of zebrafish neural crest by repressing Neurogenin 1 function.

Q9UBL6	CPNE7_HUMAN	Copine-7	10534407	Characterization of copine VII, a new member of the copine family, and its exclusion as a candidate in sporadic breast cancers with loss of heterozygosity at 16q24.3.

Q8GWE0	PP314_ARATH	Pentatricopeptide repeat-containing protein At4g16390, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q9LX29	ACR4_ARATH	Serine/threonine-protein kinase-like protein ACR4	11978870	ACR4, a putative receptor kinase gene of Arabidopsis thaliana, that is expressed in the outer cell layers of embryos and plants, is involved in proper embryogenesis.

P05050	ALKB_ECOLI	Alpha-ketoglutarate-dependent dioxygenase AlkB	16482161	Crystal structures of catalytic complexes of the oxidative DNA/RNA repair enzyme AlkB.

Q92731	ESR2_HUMAN	Estrogen receptor beta	9636657	Cloning and characterization of human estrogen receptor beta isoforms.

P60472	UPPS_ECOLI	Undecaprenyl pyrophosphate synthase	9882662	Use of genomics to identify bacterial undecaprenyl pyrophosphate synthetase: cloning, expression, and characterization of the essential uppS gene.

P39102	XDJ1_YEAST	DnaJ protein homolog XDJ1	16689936	Integral membrane proteins in the mitochondrial outer membrane of Saccharomyces cerevisiae.

P41146	OPRX_HUMAN	Nociceptin receptor	8137918	ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization.

Q6W2J9	BCOR_HUMAN	BCL-6 corepressor	10898795	BCoR, a novel corepressor involved in BCL-6 repression.

P42128	FOXK1_MOUSE	Forkhead box protein K1	8007964	Myocyte nuclear factor, a novel winged-helix transcription factor under both developmental and neural regulation in striated myocytes.

Q04844	ACHE_HUMAN	Acetylcholine receptor subunit epsilon	7531341	Congenital myasthenic syndrome caused by prolonged acetylcholine receptor channel openings due to a mutation in the M2 domain of the epsilon subunit.

Q27487	CATA1_CAEEL	Peroxisomal catalase 1	10335847	A cytosolic catalase is needed to extend adult lifespan in C. elegans daf-C and clk-1 mutants.

Q17802	CPG1_CAEEL	Chondroitin proteoglycan 1	17042944	The eggshell is required for meiotic fidelity, polar-body extrusion and polarization of the C. elegans embryo.

Q9ES87	PRSS8_RAT	Prostasin	11373334	Activation of epithelial sodium channels by prostasin in Xenopus oocytes.

O54329	LANA_STRMU	Lantibiotic mutacin-2	8021218	Isolation and biochemical characterization of a novel lantibiotic mutacin from Streptococcus mutans.

P83281	FAR8_MACRS	FMRFamide-like neuropeptide FLP8	11179812	Three more novel FMRFamide-like neuropeptide sequences from the eyestalk of the giant freshwater prawn Macrobrachium rosenbergii.

P70060	LDB1_XENLA	LIM domain-binding protein 1	9468533	Interactions between LIM domains and the LIM domain-binding protein Ldb1.

P54922	ADPRH_HUMAN	[Protein ADP-ribosylarginine] hydrolase	8349667	Cloning and site-directed mutagenesis of human ADP-ribosylarginine hydrolase.

P45748	RIMN_ECOLI	Putative ribosome maturation factor rimN	11206077	The structure of the yrdC gene product from Escherichia coli reveals a new fold and suggests a role in RNA binding.

Q9UI32	GLSL_HUMAN	Glutaminase liver isoform, mitochondrial	11163757	The C-terminus of human glutaminase L mediates association with PDZ domain-containing proteins.

O15514	RPB4_HUMAN	DNA-directed RNA polymerase II subunit RPB4	9528765	Analysis of the interaction of the novel RNA polymerase II (pol II) subunit hsRPB4 with its partner hsRPB7 and with pol II.

Q09867	EFG1P_SCHPO	rRNA-processing protein efg1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8TDZ2	MICA1_HUMAN	NEDD9-interacting protein with calponin homology and LIM domains	11827972	MICAL, a novel CasL interacting molecule, associates with vimentin.

Q03020	ISU1_YEAST	Iron sulfur cluster assembly protein 1, mitochondrial	15143178	The yeast scaffold proteins Isu1p and Isu2p are required inside mitochondria for maturation of cytosolic Fe/S proteins.

Q04228	UBX2_YEAST	UBX domain-containing protein 2	15258615	Shp1 and Ubx2 are adaptors of Cdc48 involved in ubiquitin-dependent protein degradation.

Q12277	RRP42_YEAST	Exosome complex component RRP42	10465791	The yeast exosome and human PM-Scl are related complexes of 3'-->5' exonucleases.

O14576	DC1I1_HUMAN	Cytoplasmic dynein 1 intermediate chain 1	10049579	Cloning and characterization of two cytoplasmic dynein intermediate chain genes in mouse and human.

O00541	PESC_HUMAN	Pescadillo homolog	16738141	Dominant-negative Pes1 mutants inhibit ribosomal RNA processing and cell proliferation via incorporation into the PeBoW-complex.

P49723	RIR4_YEAST	Ribonucleoside-diphosphate reductase small chain 2	10535923	Purification of ribonucleotide reductase subunits Y1, Y2, Y3, and Y4 from yeast: Y4 plays a key role in diiron cluster assembly.

Q9QWV4	MLF1_MOUSE	Myeloid leukemia factor 1	17008314	Myeloid leukemia factor 1 associates with a novel heterogeneous nuclear ribonucleoprotein U-like molecule.

P25101	EDNRA_HUMAN	Endothelin-1 receptor	9284755	Endothelin-1 and ETA receptor expression in vascular smooth muscle cells from human placenta: a new ETA receptor messenger ribonucleic acid is generated by alternative splicing of exon 3.

P52172	SRP_DROME	Box A-binding factor	8187633	A Drosophila GATA family member that binds to Adh regulatory sequences is expressed in the developing fat body.

P13569	CFTR_HUMAN	Cystic fibrosis transmembrane conductance regulator	2475911	Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA.

Q06411	SP382_YEAST	Pre-mRNA-splicing factor SPP382	16880513	Yeast ntr1/spp382 mediates prp43 function in postspliceosomes.

P36000	AP1B1_YEAST	AP-1 complex subunit beta-1	10564262	Adaptor complex-independent clathrin function in yeast.

P40582	GST1_YEAST	Glutathione S-transferase 1	9792709	A novel membrane-bound glutathione S-transferase functions in the stationary phase of the yeast Saccharomyces cerevisiae.

Q9S760	HA22D_ARATH	HVA22-like protein d	12081371	AtHVA22 gene family in Arabidopsis: phylogenetic relationship, ABA and stress regulation, and tissue-specific expression.

Q3UW12	CNGA4_MOUSE	Cyclic nucleotide-gated cation channel alpha-4	12649326	Importance of the CNGA4 channel gene for odor discrimination and adaptation in behaving mice.

Q9R233	TPSN_MOUSE	Tapasin	9716645	Sequence, linkage to H2-K, and function of mouse tapasin in MHC class I assembly.

O08760	OGG1_MOUSE	N-glycosylase/DNA lyase	9207108	Cloning and characterization of a mammalian 8-oxoguanine DNA glycosylase.

Q01105	SET_HUMAN	Protein SET	7753797	Replication factor encoded by a putative oncogene, set, associated with myeloid leukemogenesis.

Q9Y216	MTMR7_HUMAN	Myotubularin-related protein 7	9736772	Characterization of the myotubularin dual specificity phosphatase gene family from yeast to human.

Q15139	KPCD1_HUMAN	Serine/threonine-protein kinase D1	8119958	PKCmu is a novel, atypical member of the protein kinase C family.

Q9UNS1	TIM_HUMAN	Protein timeless homolog	17102137	Human Tim/Timeless-interacting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpoint.

O95747	OXSR1_HUMAN	Serine/threonine-protein kinase OSR1	14707132	Characterization of OSR1, a member of the mammalian Ste20p/germinal center kinase subfamily.

P23246	SFPQ_HUMAN	Splicing factor, proline- and glutamine-rich	11259580	PSF is a novel corepressor that mediates its effect through Sin3A and the DNA binding domain of nuclear hormone receptors.

Q3UDK1	TRAD1_MOUSE	TRAF-type zinc finger domain-containing protein 1	16221674	FLN29, a novel interferon- and LPS-inducible gene acting as a negative regulator of toll-like receptor signaling.

Q9Y7Z3	ACBP_SCHPO	Putative acyl-CoA-binding protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q10134	FEP1_SCHPO	Iron-sensing transcription factor 1	11956219	Fep1, an iron sensor regulating iron transporter gene expression in Schizosaccharomyces pombe.

Q641J8	RF12A_XENLA	E3 ubiquitin-protein ligase RNF12-A	12874135	Selective degradation of excess Ldb1 by Rnf12/RLIM confers proper Ldb1 expression levels and Xlim-1/Ldb1 stoichiometry in Xenopus organizer functions.

Q9Y7Q6	SET7_SCHPO	SET domain-containing protein 7	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9LDE4	ERF83_ARATH	Ethylene-responsive transcription factor 7	15994908	Role of an Arabidopsis AP2/EREBP-type transcriptional repressor in abscisic acid and drought stress responses.

Q12873	CHD3_HUMAN	Chromodomain-helicase-DNA-binding protein 3	9688266	Identification of a human 17p-located cDNA encoding a protein of the Snf2-like helicase family.

Q05471	SWR1_YEAST	Helicase SWR1	14562095	Global analysis of protein localization in budding yeast.

O94453	COQ4_SCHPO	Ubiquinone biosynthesis protein coq4, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P39933	TF3A_YEAST	Transcription factor IIIA	1737784	The deduced sequence of the transcription factor TFIIIA from Saccharomyces cerevisiae reveals extensive divergence from Xenopus TFIIIA.

P41817	CUP9_YEAST	Homeobox protein CUP9	7969120	Identification and analysis of a Saccharomyces cerevisiae copper homeostasis gene encoding a homeodomain protein.

O94401	YQF8_SCHPO	L-type lectin-like domain-containing protein C126.08c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O76743	GLH4_CAEEL	ATP-dependent RNA helicase glh-4	10851135	Combinatorial RNA interference indicates GLH-4 can compensate for GLH-1; these two P granule components are critical for fertility in C. elegans.

P82600	PERC_AEDAE	Chorion peroxidase	15522615	Molecular characterization of a novel peroxidase involved in Aedes aegypti chorion protein crosslinking.

Q8WYL5	SSH1_HUMAN	Protein phosphatase Slingshot homolog 1	14645219	Phosphoinositide 3-kinase-mediated activation of cofilin phosphatase Slingshot and its role for insulin-induced membrane protrusion.

P35712	SOX6_HUMAN	Transcription factor SOX-6	11255018	Cloning, characterization and chromosome mapping of the human SOX6 gene.

O74507	YJD4_SCHPO	Uncharacterized protein C594.04c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P30939	5HT1F_HUMAN	5-hydroxytryptamine receptor 1F	8380639	Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase.

Q13361	MFAP5_HUMAN	Microfibrillar-associated protein 5	8557636	Further characterization of proteins associated with elastic fiber microfibrils including the molecular cloning of MAGP-2 (MP25).

Q0PMG2	MDGA1_MOUSE	MAM domain-containing glycosylphosphatidylinositol anchor protein 1	16641224	Radial migration of superficial layer cortical neurons controlled by novel Ig cell adhesion molecule MDGA1.

O13598	YNI8_SCHPO	WW domain-containing protein C11B10.08	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P68133	ACTS_HUMAN	Actin, alpha skeletal muscle	10508519	Mutations in the skeletal muscle alpha-actin gene in patients with actin myopathy and nemaline myopathy.

P51793	CLCN4_HUMAN	H(+)/Cl(-) exchange transporter 4	8069296	A gene from the Xp22.3 region shares homology with voltage-gated chloride channels.

Q02763	TIE2_HUMAN	Angiopoietin-1 receptor	19451274	VE-PTP controls blood vessel development by balancing Tie-2 activity.

Q9LUL4	SRF7_ARATH	Protein STRUBBELIG-RECEPTOR FAMILY 7	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

P21784	RAG2_MOUSE	V(D)J recombination-activating protein 2	18033247	RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination.

P38205	NCL1_YEAST	tRNA (cytosine-5-)-methyltransferase NCL1	10445884	Multisite-specific tRNA:m5C-methyltransferase (Trm4) in yeast Saccharomyces cerevisiae: identification of the gene and substrate specificity of the enzyme.

Q03124	RSC9_YEAST	Chromatin structure-remodeling complex subunit RSC9	10025404	Histone octamer transfer by a chromatin-remodeling complex.

P82914	RT15_HUMAN	28S ribosomal protein S15, mitochondrial	11279123	The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present.

Q8UVJ6	VANG2_DANRE	Vang-like protein 2	16407953	Planar cell polarity signalling couples cell division and morphogenesis during neurulation.

Q8BHB3	LAX1_MOUSE	Lymphocyte transmembrane adapter 1	15843560	Negative regulation of lymphocyte activation by the adaptor protein LAX.

Q8IXQ6	PARP9_HUMAN	Poly [ADP-ribose] polymerase 9	11110709	BAL is a novel risk-related gene in diffuse large B-cell lymphomas that enhances cellular migration.

P08700	IL3_HUMAN	Interleukin-3	2544122	Molecular characterization of colony-stimulating factors and their receptors: human interleukin-3.

Q96242	CP74A_ARATH	Allene oxide synthase, chloroplastic	16414959	Tocopherol cyclase (VTE1) localization and vitamin E accumulation in chloroplast plastoglobule lipoprotein particles.

O33245	PSB_MYCTU	Proteasome subunit beta	20461058	Structural basis for the assembly and gate closure mechanisms of the Mycobacterium tuberculosis 20S proteasome.

Q9SY59	NFXL1_ARATH	NF-X1-type zinc finger protein NFXL1	18069941	AtNFXL1, an Arabidopsis homologue of the human transcription factor NF-X1, functions as a negative regulator of the trichothecene phytotoxin-induced defense response.

P42795	RL111_ARATH	60S ribosomal protein L11-1	7655508	Developmental regulation of ribosomal protein L16 genes in Arabidopsis thaliana.

P42680	TEC_HUMAN	Tyrosine-protein kinase Tec	7934162	Molecular cloning and analysis of the human Tec protein-tyrosine kinase.

O13539	THP2_YEAST	THO complex subunit THP2	11060033	A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae.

P21399	ACOC_HUMAN	Cytoplasmic aconitate hydratase	1903202	Homology between IRE-BP, a regulatory RNA-binding protein, aconitase, and isopropylmalate isomerase.

P49711	CTCF_HUMAN	Transcriptional repressor CTCF	16815976	CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2.

Q62417	SRBS1_MOUSE	Sorbin and SH3 domain-containing protein 1	10085297	Ponsin/SH3P12: an l-afadin- and vinculin-binding protein localized at cell-cell and cell-matrix adherens junctions.

Q9NXR8	ING3_HUMAN	Inhibitor of growth protein 3	14966270	Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans.

Q91ZP3	LPIN1_MOUSE	Phosphatidate phosphatase LPIN1	17158099	Three mammalian lipins act as phosphatidate phosphatases with distinct tissue expression patterns.

O87236	LANA1_LACLA	Lantibiotic lacticin 3147 A1	10608807	Extensive post-translational modification, including serine to D- alanine conversion, in the two-component lantibiotic, lacticin 3147.

Q10103	CHP1_SCHPO	Chromo domain-containing protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P15703	BGL2_YEAST	Glucan 1,3-beta-glucosidase	9748433	New potential cell wall glucanases of Saccharomyces cerevisiae and their involvement in mating.

O14508	SOCS2_HUMAN	Suppressor of cytokine signaling 2	9266833	Cloning and functional analysis of new members of STAT induced STAT inhibitor (SSI) family: SSI-2 and SSI-3.

P36873	PP1G_HUMAN	Serine/threonine-protein phosphatase PP1-gamma catalytic subunit	11739654	Dynamic targeting of protein phosphatase 1 within the nuclei of living mammalian cells.

Q03392	PCNA_SCHPO	Proliferating cell nuclear antigen	9891039	Fission yeast cdc24 is a replication factor C- and proliferating cell nuclear antigen-interacting factor essential for S-phase completion.

P16649	TUP1_YEAST	General transcriptional corepressor TUP1	9741624	The DNA replication and damage checkpoint pathways induce transcription by inhibition of the Crt1 repressor.

O94907	DKK1_HUMAN	Dickkopf-related protein 1	10383463	Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling.

Q8IYJ3	SYTL1_HUMAN	Synaptotagmin-like protein 1	18266782	Slp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapse.

P85008	DEF1_CRAVI	Defensin-1	16297885	Purification of a novel arthropod defensin from the American oyster, Crassostrea virginica.

Q12745	SEC39_YEAST	Protein transport protein SEC39	15242642	Exploration of essential gene functions via titratable promoter alleles.

Q9LUJ3	RDM1_ARATH	Protein RDM1	20410883	An RNA polymerase II- and AGO4-associated protein acts in RNA- directed DNA methylation.

Q15120	PDK3_HUMAN	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial	15861126	Crystal structure of pyruvate dehydrogenase kinase 3 bound to lipoyl domain 2 of human pyruvate dehydrogenase complex.

Q6UK63	PIRA_DICDI	Protein pirA	16581519	Nap1 regulates Dictyostelium cell motility and adhesion through SCAR- dependent and -independent pathways.

P39880	CUX1_HUMAN	Homeobox protein cut-like 1	1301999	Human CCAAT displacement protein is homologous to the Drosophila homeoprotein, cut.

P17538	CTRB1_HUMAN	Chymotrypsinogen B	2917002	Molecular cloning and nucleotide sequence of human pancreatic prechymotrypsinogen cDNA.

Q9NZI8	IF2B1_HUMAN	Insulin-like growth factor 2 mRNA-binding protein 1	19029303	Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs.

O74315	AMO1_SCHPO	Nucleoporin-like protein amo1	15797925	The nuclear rim protein Amo1 is required for proper microtubule cytoskeleton organisation in fission yeast.

Q07540	FRDA_YEAST	Frataxin homolog, mitochondrial	10428860	Yeast and human frataxin are processed to mature form in two sequential steps by the mitochondrial processing peptidase.

Q9PT61	OTX5B_XENLA	Homeobox protein otx5-B	16040025	The role of combinational coding by homeodomain and bHLH transcription factors in retinal cell fate specification.

Q01802	AATM_YEAST	Aspartate aminotransferase, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P40564	DJP1_YEAST	DnaJ-like protein 1	9679141	The cytosolic DnaJ-like protein djp1p is involved specifically in peroxisomal protein import.

Q86DA5	SARM1_CAEEL	Sterile alpha and TIR motif-containing protein tir-1	15625192	A Toll-interleukin 1 repeat protein at the synapse specifies asymmetric odorant receptor expression via ASK1 MAPKKK signaling.

Q8S9M1	PAP13_ARATH	Probable plastid-lipid-associated protein 13, chloroplastic	16461379	Protein profiling of plastoglobules in chloroplasts and chromoplasts. A surprising site for differential accumulation of metabolic enzymes.

Q5GM68	CAPP2_ARATH	Phosphoenolpyruvate carboxylase 2	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

Q7KNS3	LIS1_DROME	Lissencephaly-1 homolog	10498683	Lis1, the Drosophila homolog of a human lissencephaly disease gene, is required for germline cell division and oocyte differentiation.

P39083	RGA1_YEAST	Rho-type GTPase-activating protein 1	7498791	Mutation of RGA1, which encodes a putative GTPase-activating protein for the polarity-establishment protein Cdc42p, activates the pheromone-response pathway in the yeast Saccharomyces cerevisiae.

P50861	RIB4_YEAST	6,7-dimethyl-8-ribityllumazine synthase	7559556	The Saccharomyces cerevisiae RIB4 gene codes for 6,7-dimethyl-8- ribityllumazine synthase involved in riboflavin biosynthesis. Molecular characterization of the gene and purification of the encoded protein.

Q9Y6D5	BIG2_HUMAN	Brefeldin A-inhibited guanine nucleotide-exchange protein 2	10212200	Purification and cloning of a brefeldin A-inhibited guanine nucleotide-exchange protein for ADP-ribosylation factors.

P39735	SAW1_YEAST	Single-strand annealing weakened protein 1	18471978	Microarray-based genetic screen defines SAW1, a gene required for Rad1/Rad10-dependent processing of recombination intermediates.

P49283	MVL_DROME	Protein Malvolio	7621816	Malvolio, the Drosophila homologue of mouse NRAMP-1 (Bcg), is expressed in macrophages and in the nervous system and is required for normal taste behaviour.

Q86TM6	SYVN1_HUMAN	E3 ubiquitin-protein ligase synoviolin	12459480	Human HRD1 protects against ER stress-induced apoptosis through ER- associated degradation.

Q9Y794	ORC4_SCHPO	Origin recognition complex subunit 4	10535928	Identification and reconstitution of the origin recognition complex from Schizosaccharomyces pombe.

O95395	GCNT3_HUMAN	Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3	9988682	Control of O-glycan branch formation. Molecular cloning of human cDNA encoding a novel beta1,6-N-acetylglucosaminyltransferase forming core 2 and core 4.

O17581	SCC4_CAEEL	Cohesin loading complex subunit SCC4 homolog	16802858	Metazoan Scc4 homologs link sister chromatid cohesion to cell and axon migration guidance.

Q10411	SPO15_SCHPO	Sporulation-specific protein 15	10639340	S. pombe sporulation-specific coiled-coil protein Spo15p is localized to the spindle pole body and essential for its modification.

P23508	CRCM_HUMAN	Colorectal mutant cancer protein	1848370	Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers.

Q9EQW6	OLIG2_MOUSE	Oligodendrocyte transcription factor 2	14573534	Cross-repressive interaction of the Olig2 and Nkx2.2 transcription factors in developing neural tube associated with formation of a specific physical complex.

Q06AN9	CD27A_ARATH	Cell division cycle protein 27 homolog A	17944809	Specialization of CDC27 function in the Arabidopsis thaliana anaphase-promoting complex (APC/C).

Q9GZV3	SC5A7_HUMAN	High affinity choline transporter 1	12237312	Single nucleotide polymorphism of the human high affinity choline transporter alters transport rate.

Q8C7R4	UBA6_MOUSE	Ubiquitin-like modifier-activating enzyme 6	17889673	E1-L2 activates both ubiquitin and FAT10.

Q9BYC2	SCOT2_HUMAN	Succinyl-CoA:3-ketoacid-coenzyme A transferase 2, mitochondrial	11756565	Cloning and characterization of a human orthologue of testis-specific succinyl CoA:3-oxo acid CoA transferase (Scot-t) cDNA.

Q22366	RIM_CAEEL	Rab-3-interacting molecule unc-10	11559854	A post-docking role for active zone protein Rim.

P10363	PRI1_YEAST	DNA primase small subunit	2023935	Mutations in conserved yeast DNA primase domains impair DNA replication in vivo.

Q99570	PI3R4_HUMAN	Phosphoinositide 3-kinase regulatory subunit 4	19270696	Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages.

O74424	NU211_SCHPO	Nucleoporin nup211	15116432	Identification of genes encoding putative nucleoporins and transport factors in the fission yeast Schizosaccharomyces pombe: a deletion analysis.

Q9UQ84	EXO1_HUMAN	Exonuclease 1	9788596	Human exonuclease I interacts with the mismatch repair protein hMSH2.

Q14764	MVP_HUMAN	Major vault protein	7585126	The drug resistance-related protein LRP is the human major vault protein.

Q8NI27	THOC2_HUMAN	THO complex subunit 2	18974867	Recruitment of the complete hTREX complex is required for Kaposi's sarcoma-associated herpesvirus intronless mRNA nuclear export and virus replication.

Q71QF9	PRIC1_RAT	Prickle-like protein 1	14645515	REST/NRSF-interacting LIM domain protein, a putative nuclear translocation receptor.

Q13619	CUL4A_HUMAN	Cullin-4A	8681378	cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family.

Q9SAD4	ESR1_ARATH	Ethylene-responsive transcription factor ESR1	12615942	The DORNROSCHEN/ENHANCER OF SHOOT REGENERATION1 gene of Arabidopsis acts in the control of meristem cell fate and lateral organ development.

P16409	MYL3_RAT	Myosin light chain 3	2717409	Ventricular myosin light chain 1 is developmentally regulated and does not change in hypertension.

O14492	SH2B2_HUMAN	SH2B adapter protein 2	10374881	APS, an adaptor protein containing pleckstrin homology (PH) and Src homology-2 (SH2) domains inhibits the JAK-STAT pathway in collaboration with c-Cbl.

Q8VEB2	SAV1_MOUSE	Protein salvador homolog 1	20080689	Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver.

P41274	TNFL9_MOUSE	Tumor necrosis factor ligand superfamily member 9	8405064	Molecular cloning of a ligand for the inducible T cell gene 4-1BB: a member of an emerging family of cytokines with homology to tumor necrosis factor.

Q13555	KCC2G_HUMAN	Calcium/calmodulin-dependent protein kinase type II subunit gamma	9240463	Human islets of Langerhans express multiple isoforms of calcium/calmodulin-dependent protein kinase II.

P40106	GPP2_YEAST	(DL)-glycerol-3-phosphatase 2	8662716	Purification and characterization of two isoenzymes of DL-glycerol-3- phosphatase from Saccharomyces cerevisiae. Identification of the corresponding GPP1 and GPP2 genes and evidence for osmotic regulation of Gpp2p expression by the osmosensing mitogen-activated protein kinase signal transduction pathway.

P03986	TRGC2_HUMAN	T-cell receptor gamma-2 chain C region	3458221	Cloning and sequence analysis of complementary DNA encoding an aberrantly rearranged human T-cell gamma chain.

P34394	MPS4_CAEEL	MinK-related peptide, potassium channel accessory subunit protein 4	15799965	A family of K+ channel ancillary subunits regulate taste sensitivity in Caenorhabditis elegans.

Q93243	NAS37_CAEEL	Zinc metalloproteinase nas-37	15255192	Metalloproteases with EGF, CUB, and thrombospondin-1 domains function in molting of Caenorhabditis elegans.

O08812	CTR3_RAT	Cationic amino acid transporter 3	9079705	Cloning and characterization of a brain-specific cationic amino acid transporter.

P0C0W1	RS22A_YEAST	40S ribosomal protein S22-A	6814480	Isolation of seventeen proteins and amino-terminal amino acid sequences of eight proteins from cytoplasmic ribosomes of yeast.

P63005	LIS1_MOUSE	Platelet-activating factor acetylhydrolase IB subunit alpha	12950100	A study of the nature of embryonic lethality in LIS1-/- mice.

O35464	SEM6A_MOUSE	Semaphorin-6A	10993894	The orthologous human and murine semaphorin 6A-1 proteins (SEMA6A- 1/Sema6A-1) bind to the enabled/vasodilator-stimulated phosphoprotein- like protein (EVL) via a novel carboxyl-terminal zyxin-like domain.

Q9Z515	WHIA_STRCO	Sporulation transcription regulator whiA	10986251	WhiA, a protein of unknown function conserved among gram-positive bacteria, is essential for sporulation in Streptomyces coelicolor A3(2).

O35240	ACCN3_RAT	Amiloride-sensitive cation channel 3	9261094	Molecular cloning of a non-inactivating proton-gated Na+ channel specific for sensory neurons.

Q14257	RCN2_HUMAN	Reticulocalbin-2	8034671	The endoplasmic reticulum calcium-binding protein of 55 kDa is a novel EF-hand protein retained in the endoplasmic reticulum by a carboxyl-terminal His-Asp-Glu-Leu motif.

Q13546	RIPK1_HUMAN	Receptor-interacting serine/threonine-protein kinase 1	8612133	TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex.

O42979	YGZA_SCHPO	PHO85 cyclin-like protein C20F10.10	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9JJ19	NHRF1_RAT	Na(+)/H(+) exchange regulatory cofactor NHE-RF1	11457882	Loss of glomerular foot processes is associated with uncoupling of podocalyxin from the actin cytoskeleton.

P16562	CRIS2_HUMAN	Cysteine-rich secretory protein 2	8665901	The human cysteine-rich secretory protein (CRISP) family. Primary structure and tissue distribution of CRISP-1, CRISP-2 and CRISP-3.

Q9WV48	SHAN1_RAT	SH3 and multiple ankyrin repeat domains protein 1	10488079	Synamon, a novel neuronal protein interacting with synapse-associated protein 90/postsynaptic density-95-associated protein.

P63218	GBG5_HUMAN	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5	9790912	Structure of human G protein Ggamma5 gene GNG5.

Q12043	TGL5_YEAST	Lipase 5	14562095	Global analysis of protein localization in budding yeast.

P54070	KTR6_YEAST	Mannosyltransferase KTR6	9218445	MNN6, a member of the KRE2/MNT1 family, is the gene for mannosylphosphate transfer in Saccharomyces cerevisiae.

Q1W617	SHRM4_MOUSE	Protein Shroom4	17009331	Shroom4 (Kiaa1202) is an actin-associated protein implicated in cytoskeletal organization.

Q12495	RLF2_YEAST	Chromatin assembly factor 1 subunit p90	9030688	RLF2, a subunit of yeast chromatin assembly factor-I, is required for telomeric chromatin function in vivo.

P53219	YG1L_YEAST	Uncharacterized abhydrolase domain-containing protein YGR031W	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

P14068	XPO1_SCHPO	Exportin-1	2647765	Higher order chromosome structure is affected by cold-sensitive mutations in a Schizosaccharomyces pombe gene crm1+ which encodes a 115-kD protein preferentially localized in the nucleus and its periphery.

Q8L5Y6	CAND1_ARATH	Cullin-associated NEDD8-dissociated protein 1	15208392	Arabidopsis ETA2, an apparent ortholog of the human cullin- interacting protein CAND1, is required for auxin responses mediated by the SCF(TIR1) ubiquitin ligase.

Q9VTE2	SUUR_DROME	Protein suppressor of underreplication	12456726	Overexpression of the SuUR gene induces reversible modifications at pericentric, telomeric and intercalary heterochromatin of Drosophila melanogaster polytene chromosomes.

Q38870	CDPK2_ARATH	Calcium-dependent protein kinase 2	11891256	An Arabidopsis calcium-dependent protein kinase is associated with the endoplasmic reticulum.

P78543	BTG2_HUMAN	Protein BTG2	8944033	Identification of BTG2, an antiproliferative p53-dependent component of the DNA damage cellular response pathway.

Q4VCS5	AMOT_HUMAN	Angiomotin	16043488	Angiomotin regulates endothelial cell-cell junctions and cell motility.

P09938	RIR2_YEAST	Ribonucleoside-diphosphate reductase small chain 1	12732713	Subcellular localization of yeast ribonucleotide reductase regulated by the DNA replication and damage checkpoint pathways.

Q16637	SMN_HUMAN	Survival motor neuron protein	12975319	Unique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processing.

Q10749	VMMOC_NAJMO	Zinc metalloproteinase mocarhagin-1	8664285	Mocarhagin, a novel cobra venom metalloproteinase, cleaves the platelet von Willebrand factor receptor glycoprotein Ibalpha. Identification of the sulfated tyrosine/anionic sequence Tyr-276-Glu- 282 of glycoprotein Ibalpha as a binding site for von Willebrand factor and alpha-thrombin.

Q9ER63	TNR23_MOUSE	Tumor necrosis factor receptor superfamily member 23	12466268	Identification of a new murine tumor necrosis factor receptor locus that contains two novel murine receptors for tumor necrosis factor- related apoptosis-inducing ligand (TRAIL).

Q9Y606	TRUA_HUMAN	tRNA pseudouridine synthase A, mitochondrial	10094309	Cloning and characterization of a mammalian pseudouridine synthase.

P51816	AFF2_HUMAN	AF4/FMR2 family member 2	19136466	FRAXE-associated mental retardation protein (FMR2) is an RNA-binding protein with high affinity for G-quartet RNA forming structure.

P32322	P5CR1_HUMAN	Pyrroline-5-carboxylate reductase 1, mitochondrial	1730675	Cloning human pyrroline-5-carboxylate reductase cDNA by complementation in Saccharomyces cerevisiae.

O43761	SNG3_HUMAN	Synaptogyrin-3	9760194	Characterization of the human synaptogyrin gene family.

Q9XIE2	AB36G_ARATH	ABC transporter G family member 36	16618929	Mapping the Arabidopsis organelle proteome.

Q04739	GAL83_YEAST	SNF1 protein kinase subunit beta-3	9121458	The Snf1 protein kinase and its activating subunit, Snf4, interact with distinct domains of the Sip1/Sip2/Gal83 component in the kinase complex.

Q04900	MUC24_HUMAN	Sialomucin core protein 24	10878358	CD164 monoclonal antibodies that block hemopoietic progenitor cell adhesion and proliferation interact with the first mucin domain of the CD164 receptor.

P51159	RB27A_HUMAN	Ras-related protein Rab-27A	17237785	Secretory cytotoxic granule maturation and exocytosis require the effector protein hMunc13-4.

P48065	S6A12_HUMAN	Sodium- and chloride-dependent betaine transporter	7861179	Cloning and expression of a betaine/GABA transporter from human brain.

P38573	UPK1B_BOVIN	Uroplakin-1b	12475947	Specific heterodimer formation is a prerequisite for uroplakins to exit from the endoplasmic reticulum.

Q9H2H0	CXXC4_HUMAN	CXXC-type zinc finger protein 4	11113207	Inhibition of the Wnt signaling pathway by Idax, a novel Dvl-binding protein.

P14359	SNA3_YEAST	Protein SNA3	11566881	Sorting of proteins into multivesicular bodies: ubiquitin-dependent and -independent targeting.

Q712U5	ARP19_RAT	cAMP-regulated phosphoprotein 19	2158525	Differential expression of ARPP-16 and ARPP-19, two highly related cAMP-regulated phosphoproteins, one of which is specifically associated with dopamine-innervated brain regions.

Q93380	UNC93_CAEEL	Putative potassium channel regulatory protein unc-93	1313436	The Caenorhabditis elegans unc-93 gene encodes a putative transmembrane protein that regulates muscle contraction.

Q9P7K1	YJN4_SCHPO	Uncharacterized protein C24B10.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9SAF1	ARP3_ARATH	Actin-related protein 3	17267444	The role of Arabidopsis SCAR genes in ARP2-ARP3-dependent cell morphogenesis.

O43927	CXL13_HUMAN	C-X-C motif chemokine 13	9463416	B cell-attracting chemokine 1, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5.

Q9P6H9	REB1_SCHPO	DNA-binding protein reb1	9016645	Molecular cloning and analysis of Schizosaccharomyces pombe Reb1p: sequence-specific recognition of two sites in the far upstream rDNA intergenic spacer.

Q9H158	PCDC1_HUMAN	Protocadherin alpha-C1	10380929	A striking organization of a large family of human neural cadherin- like cell adhesion genes.

Q92959	SO2A1_HUMAN	Solute carrier organic anion transporter family member 2A1	8787677	Cloning, in vitro expression, and tissue distribution of a human prostaglandin transporter cDNA(hPGT).

Q794F9	4F2_RAT	4F2 cell-surface antigen heavy chain	9480885	Cloning and functional expression of a cDNA from rat jejunal epithelium encoding a protein (4F2hc) with system y+L amino acid transport activity.

O95379	TFIP8_HUMAN	Tumor necrosis factor alpha-induced protein 8	10644768	Identification of a novel tumor necrosis factor-alpha-inducible gene, SCC-S2, containing the consensus sequence of a death effector domain of fas-associated death domain-like interleukin-1beta-converting enzyme-inhibitory protein.

O94475	YC67_SCHPO	Uncharacterized protein C1919.07	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8L840	RQL4A_ARATH	ATP-dependent DNA helicase Q-like 4A	18000056	Two closely related RecQ helicases have antagonistic roles in homologous recombination and DNA repair in Arabidopsis thaliana.

Q8LGE3	ARP6_ARATH	Actin-related protein 6	17470967	Arabidopsis homologs of components of the SWR1 complex regulate flowering and plant development.

P47118	YAE1_YEAST	Uncharacterized protein YAE1	14562095	Global analysis of protein localization in budding yeast.

Q14896	MYPC3_HUMAN	Myosin-binding protein C, cardiac-type	11815426	Sarcomere protein gene mutations in hypertrophic cardiomyopathy of the elderly.

Q80WG5	LRC8A_MOUSE	Leucine-rich repeat-containing protein 8A	14660746	A congenital mutation of the novel gene LRRC8 causes agammaglobulinemia in humans.

Q81CK1	KYNB_BACCR	Kynurenine formamidase	14592712	Aerobic tryptophan degradation pathway in bacteria: novel kynurenine formamidase.

Q9SAJ3	FTSHC_ARATH	ATP-dependent zinc metalloprotease FTSH 12, chloroplastic	14630971	Coordinated regulation and complex formation of yellow variegated1 and yellow variegated2, chloroplastic FtsH metalloproteases involved in the repair cycle of photosystem II in Arabidopsis thylakoid membranes.

Q06835	RDS3_YEAST	Pre-mRNA-splicing factor RDS3	11943786	New regulators of drug sensitivity in the family of yeast zinc cluster proteins.

P78929	COFI_SCHPO	Cofilin	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O70145	NCF2_MOUSE	Neutrophil cytosol factor 2	9490028	Functional modules and expression of mouse p40(phox) and p67(phox), SH3-domain-containing proteins involved in the phagocyte NADPH oxidase complex.

O60437	PEPL_HUMAN	Periplakin	12244133	Binding of protein kinase B to the plakin family member periplakin.

O95167	NDUA3_HUMAN	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

Q9UKV0	HDAC9_HUMAN	Histone deacetylase 9	10655483	Identification of a transcriptional repressor related to the noncatalytic domain of histone deacetylases 4 and 5.

Q8WUI4	HDAC7_HUMAN	Histone deacetylase 7	20188095	Protein kinase C-related kinase targets nuclear localization signals in a subset of class IIa histone deacetylases.

Q08412	CUE5_YEAST	Ubiquitin-binding protein CUE5	12628920	A ubiquitin-binding motif required for intramolecular monoubiquitylation, the CUE domain.

Q9C026	TRIM9_HUMAN	E3 ubiquitin-protein ligase TRIM9	11331580	The tripartite motif family identifies cell compartments.

Q9UNA0	ATS5_HUMAN	A disintegrin and metalloproteinase with thrombospondin motifs 5	10438522	Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family.

Q8WXD5	GEMI6_HUMAN	Gem-associated protein 6	11748230	Purification of native survival of motor neurons complexes and identification of Gemin6 as a novel component.

P28272	PYRD_YEAST	Dihydroorotate dehydrogenase	1409592	Divergent evolution of pyrimidine biosynthesis between anaerobic and aerobic yeasts.

Q9Y468	LMBL1_HUMAN	Lethal(3)malignant brain tumor-like protein	12588862	The human L(3)MBT Polycomb group protein is a transcriptional repressor and interacts physically and functionally with TEL (ETV6).

Q07817	B2CL1_HUMAN	Bcl-2-like protein 1	12011449	Siva-1 binds to and inhibits BCL-X(L)-mediated protection against UV radiation-induced apoptosis.

Q08464	FZD2_RAT	Frizzled-2	1334084	Two homologs of the Drosophila polarity gene frizzled (fz) are widely expressed in mammalian tissues.

Q68SA9	ATS7_MOUSE	A disintegrin and metalloproteinase with thrombospondin motifs 7	15192113	ADAMTS7B, the full-length product of the ADAMTS7 gene, is a chondroitin sulfate proteoglycan containing a mucin domain.

P17839	AG_ARATH	Floral homeotic protein AGAMOUS	9418042	Specific interactions between the K domains of AG and AGLs, members of the MADS domain family of DNA binding proteins.

P04631	S100B_RAT	Protein S100-B	19910580	S100B interaction with the receptor for advanced glycation end products (RAGE): a novel receptor-mediated mechanism for myocyte apoptosis postinfarction.

P40360	NAGS_YEAST	Amino-acid acetyltransferase, mitochondrial	205532	Arginine metabolism in Saccharomyces cerevisiae: subcellular localization of the enzymes.

O75030	MITF_HUMAN	Microphthalmia-associated transcription factor	9647758	Identification of a novel isoform of microphthalmia-associated transcription factor that is enriched in retinal pigment epithelium.

Q61169	GATA6_MOUSE	Transcription factor GATA-6	16199866	LMCD1/Dyxin is a novel transcriptional cofactor that restricts GATA6 function by inhibiting DNA binding.

Q9NVC6	MED17_HUMAN	Mediator of RNA polymerase II transcription subunit 17	12584197	Identification of mammalian Mediator subunits with similarities to yeast Mediator subunits Srb5, Srb6, Med11, and Rox3.

P02918	PBPA_ECOLI	Penicillin-binding protein 1A	7006606	Dual enzyme activities of cell wall peptidoglycan synthesis, peptidoglycan transglycosylase and penicillin-sensitive transpeptidase, in purified preparations of Escherichia coli penicillin-binding protein 1A.

O43603	GALR2_HUMAN	Galanin receptor type 2	9685625	Molecular characterization, pharmacological properties and chromosomal localization of the human GALR2 galanin receptor.

Q91924	SNAI2_XENLA	Zinc finger protein SNAI2	12490555	Snail precedes slug in the genetic cascade required for the specification and migration of the Xenopus neural crest.

Q9HD42	CHM1A_HUMAN	Charged multivesicular body protein 1a	11559748	CHMP1 functions as a member of a newly defined family of vesicle trafficking proteins.

Q9D666	SUN1_MOUSE	SUN domain-containing protein 1	19933576	Mammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processes.

O00168	PLM_HUMAN	Phospholemman	9169143	Characterization of the human and rat phospholemman (PLM) cDNAs and localization of the human PLM gene to chromosome 19q13.1.

P25054	APC_HUMAN	Adenomatous polyposis coli protein	10947987	Asef, a link between the tumor suppressor APC and G-protein signaling.

Q9CAJ0	P2C16_ARATH	Protein phosphatase 2C 16	19407143	Regulators of PP2C phosphatase activity function as abscisic acid sensors.

Q8RWN7	P2C32_ARATH	Protein phosphatase 2C 32	17079273	POL and PLL1 phosphatases are CLAVATA1 signaling intermediates required for Arabidopsis shoot and floral stem cells.

P08069	IGF1R_HUMAN	Insulin-like growth factor 1 receptor	7541045	Non-SH2 domains within insulin receptor substrate-1 and SHC mediate their phosphotyrosine-dependent interaction with the NPEY motif of the insulin-like growth factor I receptor.

Q9M0Z6	MSRB3_ARATH	Peptide methionine sulfoxide reductase B3	17956860	Role of the methionine sulfoxide reductase MsrB3 in cold acclimation in Arabidopsis.

Q9UBB4	ATX10_HUMAN	Ataxin-10	16498633	Ataxin 10 induces neuritogenesis via interaction with G-protein beta2 subunit.

Q03010	UME1_YEAST	Transcriptional regulatory protein UME1	16314178	Stable incorporation of sequence specific repressors Ash1 and Ume6 into the Rpd3L complex.

P91124	RIC19_CAEEL	Resistance to inhibitors of cholinesterase protein 19	11029035	The diabetes autoantigen ICA69 and its Caenorhabditis elegans homologue, ric-19, are conserved regulators of neuroendocrine secretion.

Q8SY61	OB56D_DROME	General odorant-binding protein 56d	11729153	A large family of divergent Drosophila odorant-binding proteins expressed in gustatory and olfactory sensilla.

P93045	BSH_ARATH	Chromatin structure-remodeling complex protein BSH	10325430	Identification and analysis of the Arabidopsis thaliana BSH gene, a member of the SNF5 gene family.

P32566	SMI1_YEAST	Cell wall assembly regulator SMI1	11410349	Interaction of Knr4 protein, a protein involved in cell wall synthesis, with tyrosine tRNA synthetase encoded by TYS1 in Saccharomyces cerevisiae.

Q9P6S5	ASK1_SCHPO	DASH complex subunit ask1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P29120	NEC1_HUMAN	Neuroendocrine convertase 1	9207799	Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene.

P09038	FGF2_HUMAN	Heparin-binding growth factor 2	16257968	Identification of the fibroblast growth factor (FGF)-interacting domain in a secreted FGF-binding protein by phage display.

Q8H1R0	PYL10_ARATH	Abscisic acid receptor PYL10	19874541	PYR/PYL/RCAR family members are major in-vivo ABI1 protein phosphatase 2C-interacting proteins in Arabidopsis.

Q96RL1	UIMC1_HUMAN	BRCA1-A complex subunit RAP80	12080054	RAP80: a novel nuclear protein that interacts with the retinoid- related testis-associated receptor.

Q08911	FDH1_YEAST	Formate dehydrogenase 1	11921099	Functional analysis of structural genes for NAD(+)-dependent formate dehydrogenase in Saccharomyces cerevisiae.

Q9CZP0	UFSP1_MOUSE	Ufm1-specific protease 1	17182609	Two novel ubiquitin-fold modifier 1 (Ufm1)-specific Proteases, UfSP1 and UfSP2.

P29250	LOX2_ORYSJ	Lipoxygenase 2	1597177	cDNA cloning of rice lipoxygenase L-2 and characterization using an active enzyme expressed from the cDNA in Escherichia coli.

P62861	RS30_HUMAN	40S ribosomal protein S30	8395683	fau cDNA encodes a ubiquitin-like-S30 fusion protein and is expressed as an antisense sequence in the Finkel-Biskis-Reilly murine sarcoma virus.

Q9P7H7	ILM1_SCHPO	Protein ilm1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O43303	CE110_HUMAN	Centrosomal protein of 110 kDa	17681131	Plk4-induced centriole biogenesis in human cells.

Q5M834	DTBP1_RAT	Dysbindin	17989303	Evidence that the BLOC-1 protein dysbindin modulates dopamine D2 receptor internalization and signaling but not D1 internalization.

Q8CDG1	PIWL2_MOUSE	Piwi-like protein 2	19465913	Loss of the Mili-interacting Tudor domain-containing protein-1 activates transposons and alters the Mili-associated small RNA profile.

Q10331	NU107_SCHPO	Nucleoporin nup107	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8VBX6	MPDZ_MOUSE	Multiple PDZ domain protein	11689568	Multi-PDZ domain protein 1 (MUPP1) is concentrated at tight junctions through its possible interaction with claudin-1 and junctional adhesion molecule.

Q18221	SET2_CAEEL	Probable histone-lysine N-methyltransferase set-2	17967446	Antagonistic functions of SET-2/SET1 and HPL/HP1 proteins in C. elegans development.

Q13163	MP2K5_HUMAN	Dual specificity mitogen-activated protein kinase kinase 5	7759517	Components of a new human protein kinase signal transduction pathway.

P29746	BNB_DROME	Protein bangles and beads	1551578	Genetic and developmental analysis of polytene section 17 of the X chromosome of Drosophila melanogaster.

Q8LAD0	PDX2_ARATH	Pyridoxal biosynthesis protein PDX2	16157873	Vitamin B6 biosynthesis in higher plants.

Q9W589	OFUT2_DROME	GDP-fucose protein O-fucosyltransferase 2	16464857	Protein O-fucosyltransferase 2 adds O-fucose to thrombospondin type 1 repeats.

Q61164	CTCF_MOUSE	Transcriptional repressor CTCF	16951251	CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus.

P15043	RECQ_ECOLI	ATP-dependent DNA helicase recQ	2164680	Escherichia coli RecQ protein is a DNA helicase.

Q64559	BACH_RAT	Cytosolic acyl coenzyme A thioester hydrolase	9163348	Peroxisome proliferator-induced acyl-CoA thioesterase from rat liver cytosol: molecular cloning and functional expression in Chinese hamster ovary cells.

P84022	SMAD3_HUMAN	Mothers against decapentaplegic homolog 3	16200078	Cloning and functional characterization of a new Ski homolog, Fussel- 18, specifically expressed in neuronal tissues.

P06700	SIR2_YEAST	NAD-dependent histone deacetylase SIR2	10219244	Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex.

Q8I8U7	TRA1_DROME	Transcription-associated protein 1	12697829	Two Drosophila Ada2 homologues function in different multiprotein complexes.

P11234	RALB_HUMAN	Ras-related protein Ral-B	18756269	Distinct roles of RalA and RalB in the progression of cytokinesis are supported by distinct RalGEFs.

P06182	CCHL_YEAST	Cytochrome c heme lyase	3034577	Identification and sequence of the gene encoding cytochrome c heme lyase in the yeast Saccharomyces cerevisiae.

O13851	DLP1_SCHPO	Decaprenyl-diphosphate synthase subunit 2	14519123	Fission yeast decaprenyl diphosphate synthase consists of Dps1 and the newly characterized Dlp1 protein in a novel heterotetrameric structure.

Q9Y6N7	ROBO1_HUMAN	Roundabout homolog 1	10892742	Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the roundabout receptor.

P00167	CYB5_HUMAN	Cytochrome b5	1712589	The human liver and reticulocyte cytochrome b5 mRNAs are products from a single gene.

P52952	NKX25_HUMAN	Homeobox protein Nkx-2.5	10587520	Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathways.

P22830	HEMH_HUMAN	Ferrochelatase, mitochondrial	1376018	A molecular defect in human protoporphyria.

O16850	FOXO_CAEEL	Forkhead box protein O	12750521	Regulation of aging and age-related disease by DAF-16 and heat-shock factor.

Q84KJ7	AMT21_ORYSJ	Ammonium transporter 2 member 1	12610225	Constitutive expression of a novel-type ammonium transporter OsAMT2 in rice plants.

P40030	ERG28_YEAST	Ergosterol biosynthetic protein 28	15995173	Erg28p is a key protein in the yeast sterol biosynthetic enzyme complex.

P01275	GLUC_HUMAN	Glucagon	12626323	Glucagon and regulation of glucose metabolism.

Q9W497	GR05A_DROME	Gustatory receptor for trehalose	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

Q99835	SMO_HUMAN	Smoothened homolog	8906787	The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog.

O95672	ECEL1_HUMAN	Endothelin-converting enzyme-like 1	9931490	XCE, a new member of the endothelin-converting enzyme and neutral endopeptidase family, is preferentially expressed in the CNS.

P84914	VP13B_POLPI	Venom protein 13b	15150833	Mass spectrometric characterization of two novel inflammatory peptides from the venom of the social wasp Polybia paulista.

P08638	LEUR_YEAST	Regulatory protein LEU3	2823102	LEU3 of Saccharomyces cerevisiae encodes a factor for control of RNA levels of a group of leucine-specific genes.

P82176	IMPI_GALME	Inducible metalloproteinase inhibitor protein	15115439	Cloning and expression of an inhibitor of microbial metalloproteinases from insects contributing to innate immunity.

O75618	DEDD_HUMAN	Death effector domain-containing protein	9774341	DEDD, a novel death effector domain-containing protein, targeted to the nucleolus.

Q9STE8	TC753_ARATH	Protein TOC75-3, chloroplastic	15908591	A molecular-genetic study of the Arabidopsis toc75 gene family.

Q9JIS1	RIMS2_RAT	Regulating synaptic membrane exocytosis protein 2	16732694	Structural basis for a Munc13-1 homodimer to Munc13-1/RIM heterodimer switch.

P52166	PSN_CAEEL	Presenilin sel-12	7566091	Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene.

O74778	BTB2_SCHPO	BTB/POZ domain-containing protein 2	14527422	BTB/POZ domain proteins are putative substrate adaptors for cullin 3 ubiquitin ligases.

Q61955	KLK8_MOUSE	Kallikrein-8	11273653	Abnormalities of synapses and neurons in the hippocampus of neuropsin-deficient mice.

Q9Y1B2	ORC6_DROME	Origin recognition complex subunit 6	10346817	Assembly of functionally active Drosophila origin recognition complex from recombinant proteins.

O70374	MTG8R_MOUSE	Protein CBFA2T2	16227606	Mtgr1 is a transcriptional corepressor that is required for maintenance of the secretory cell lineage in the small intestine.

Q9C5C2	BGL37_ARATH	Myrosinase 2	19433491	Myrosinases, TGG1 and TGG2, redundantly function in ABA and MeJA signaling in Arabidopsis guard cells.

P02692	FABPL_RAT	Fatty acid-binding protein, liver	3478711	Liver fatty acid binding protein is the mitosis-associated polypeptide target of a carcinogen in rat hepatocytes.

Q07001	ACHD_HUMAN	Acetylcholine receptor subunit delta	8872460	New mutations in acetylcholine receptor subunit genes reveal heterogeneity in the slow-channel congenital myasthenic syndrome.

Q9VCP0	ELOA1_DROME	Transcription elongation factor B polypeptide 3	15509793	In vivo requirement of the RNA polymerase II elongation factor elongin A for proper gene expression and development.

Q9Y487	VPP2_HUMAN	V-type proton ATPase 116 kDa subunit a isoform 2	16415858	V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway.

P13716	HEM2_HUMAN	Delta-aminolevulinic acid dehydratase	3463993	Human delta-aminolevulinate dehydratase: nucleotide sequence of a full-length cDNA clone.

P20659	TRX_DROME	Histone-lysine N-methyltransferase trithorax	12408863	Drosophila Enhancer of zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites.

Q8INK9	MSRB_DROME	Methionine-R-sulfoxide reductase B1	12145281	Reaction mechanism, evolutionary analysis, and role of zinc in Drosophila methionine-R-sulfoxide reductase.

Q8NG31	CASC5_HUMAN	Protein CASC5	17981135	Human Blinkin/AF15q14 is required for chromosome alignment and the mitotic checkpoint through direct interaction with Bub1 and BubR1.

Q99PE9	ARL4D_MOUSE	ADP-ribosylation factor-like protein 4D	12414990	A developmentally regulated ARF-like 5 protein (ARL5), localized to nuclei and nucleoli, interacts with heterochromatin protein 1.

P32573	SPS19_YEAST	Peroxisomal 2,4-dienoyl-CoA reductase SPS19	7969036	Identification of a sporulation-specific promoter regulating divergent transcription of two novel sporulation genes in Saccharomyces cerevisiae.

P32004	L1CAM_HUMAN	Neural cell adhesion molecule L1	1769655	Molecular structure and functional testing of human L1CAM: an interspecies comparison.

Q9BW71	HIRP3_HUMAN	HIRA-interacting protein 3	9710638	Core histones and HIRIP3, a novel histone-binding protein, directly interact with WD repeat protein HIRA.

Q93ZB9	FACR3_ARATH	Fatty acyl-CoA reductase 3	16980563	CER4 encodes an alcohol-forming fatty acyl-coenzyme A reductase involved in cuticular wax production in Arabidopsis.

Q09777	RGS1_SCHPO	Regulator of G-protein signaling 1	11554925	The RGS domain-containing fission yeast protein, Rgs1p, regulates pheromone signalling and is required for mating.

Q08777	MCH5_YEAST	Riboflavin transporter MCH5	11536335	The putative monocarboxylate permeases of the yeast Saccharomyces cerevisiae do not transport monocarboxylic acids across the plasma membrane.

Q9GZS9	CHST5_HUMAN	Carbohydrate sulfotransferase 5	10491328	Cloning and characterization of a mammalian N-acetylglucosamine-6- sulfotransferase that is highly restricted to intestinal tissue.

Q09599	SLBP_CAEEL	Histone RNA hairpin-binding protein	11782412	The stem-loop binding protein CDL-1 is required for chromosome condensation, progression of cell death and morphogenesis in Caenorhabditis elegans.

P51142	DVL2_XENLA	Segment polarity protein dishevelled homolog DVL-2	12574121	Association of Dishevelled with Eph tyrosine kinase receptor and ephrin mediates cell repulsion.

P47979	ZFS1_SCHPO	Zinc finger protein zfs1	10462526	The S. pombe zfs1 gene is required to prevent septation if mitotic progression is inhibited.

O76360	EGL4_CAEEL	cGMP-dependent protein kinase egl-4	12571101	Cyclic GMP-dependent protein kinase EGL-4 controls body size and lifespan in C elegans.

P97839	DLGP4_RAT	Disks large-associated protein 4	9115257	SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density.

Q9LYQ4	PR1B6_ARATH	PRA1 family protein B6	18583532	The PRA1 gene family in Arabidopsis.

Q99207	NOP14_YEAST	Nucleolar complex protein 14	12446671	A Noc complex specifically involved in the formation and nuclear export of ribosomal 40 S subunits.

P89105	CTR9_YEAST	RNA polymerase-associated protein CTR9	15643076	Separation of the Saccharomyces cerevisiae Paf1 complex from RNA polymerase II results in changes in its subnuclear localization.

P46664	PURA2_MOUSE	Adenylosuccinate synthetase isozyme 2	12482871	Variations in the response of mouse isozymes of adenylosuccinate synthetase to inhibitors of physiological relevance.

O76036	NCTR1_HUMAN	Natural cytotoxicity triggering receptor 1	9730896	Molecular cloning of NKp46: a novel member of the immunoglobulin superfamily involved in triggering of natural cytotoxicity.

Q8N5C8	TAB3_HUMAN	TGF-beta-activated kinase 1 and MAP3K7-binding protein 3	17449468	RBCK1 negatively regulates tumor necrosis factor- and interleukin-1- triggered NF-kappaB activation by targeting TAB2/3 for degradation.

Q06495	NPT2A_HUMAN	Sodium-dependent phosphate transport protein 2A	8327470	Expression cloning of human and rat renal cortex Na/Pi cotransport.

O94569	YGDC_SCHPO	Uncharacterized transcriptional regulatory protein C1773.12	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P28222	5HT1B_HUMAN	5-hydroxytryptamine receptor 1B	1315531	Molecular cloning and functional characterization of a human 5-HT1B serotonin receptor: a homologue of the rat 5-HT1B receptor with 5- HT1D-like pharmacological specificity.

O95166	GBRAP_HUMAN	Gamma-aminobutyric acid receptor-associated protein	11146101	Interaction of the Unc-51-like kinase and microtubule-associated protein light chain 3 related proteins in the brain: possible role of vesicular transport in axonal elongation.

P15204	THAA_XENLA	Thyroid hormone receptor alpha-A	2402492	Xenopus laevis alpha and beta thyroid hormone receptors.

P24719	MEK1_YEAST	Meiosis-specific serine/threonine-protein kinase MEK1	1752435	A meiosis-specific protein kinase homolog required for chromosome synapsis and recombination.

Q14152	EIF3A_HUMAN	Eukaryotic translation initiation factor 3 subunit A	17581632	Reconstitution reveals the functional core of mammalian eIF3.

Q61371	IFT88_MOUSE	Intraflagellar transport protein 88 homolog	20230748	Ofd1, a human disease gene, regulates the length and distal structure of centrioles.

P42699	PLAS2_ARATH	Plastocyanin major isoform, chloroplastic	11826309	Central functions of the lumenal and peripheral thylakoid proteome of Arabidopsis determined by experimentation and genome-wide prediction.

Q9R000	ITBP2_MOUSE	Integrin beta-1-binding protein 2	10506186	Melusin is a new muscle-specific interactor for beta(1) integrin cytoplasmic domain.

Q9LLR6	NLTP4_ARATH	Non-specific lipid-transfer protein 4	10940464	Lipid transfer proteins are encoded by a small multigene family in Arabidopsis thaliana.

P97852	DHB4_RAT	Peroxisomal multifunctional enzyme type 2	8913347	Rat 17 beta-hydroxysteroid dehydrogenase type IV is a novel peroxisome proliferator-inducible gene.

P39980	SIT1_YEAST	Siderophore iron transporter 1	10748025	Siderophore-iron uptake in Saccharomyces cerevisiae. Identification of ferrichrome and fusarinine transporters.

Q9Z340	PARD3_RAT	Partitioning defective 3 homolog	18082612	PDZ domains of Par-3 as potential phosphoinositide signaling integrators.

P29674	LHX1_XENLA	LIM/homeobox protein Lhx1	11112328	A role for Xlim-1 in pronephros development in Xenopus laevis.

Q6UY27	PATE2_HUMAN	Prostate and testis expressed protein 2	18387948	PATE gene clusters code for multiple, secreted TFP/Ly-6/uPAR proteins that are expressed in reproductive and neuron-rich tissues and possess neuromodulatory activity.

P61020	RAB5B_HUMAN	Ras-related protein Rab-5B	1541686	Identification and subcellular localization of human rab5b, a new member of the ras-related superfamily of GTPases.

O43044	NU120_SCHPO	Nucleoporin nup120	15116432	Identification of genes encoding putative nucleoporins and transport factors in the fission yeast Schizosaccharomyces pombe: a deletion analysis.

Q24192	RHOL_DROME	Ras-like GTP-binding protein RhoL	9197407	Molecular cloning and characterization of Drosophila genes encoding small GTPases of the rab and rho families.

Q63202	ADAM2_RAT	Disintegrin and metalloproteinase domain-containing protein 2	9358007	Cloning and sequence analysis of rat fertilin alpha and beta - developmental expression, processing and immunolocalization.

Q9IAX2	IOD2_CHICK	Type II iodothyronine deiodinase	10318780	Cloning and expression of the chicken type 2 iodothyronine 5'- deiodinase.

P53201	SWC4_YEAST	SWR1-complex protein 4	15045029	A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin.

P70581	NUPL1_RAT	Nucleoporin p58/p45	9795236	cDNA cloning and analysis of the expression of nucleoporin p45.

O09175	AMPB_RAT	Aminopeptidase B	8940051	Molecular cloning and expression of rat liver aminopeptidase B.

Q9NS91	RAD18_HUMAN	E3 ubiquitin-protein ligase RAD18	10884424	Dysfunction of human Rad18 results in defective postreplication repair and hypersensitivity to multiple mutagens.

Q924H7	WAC_MOUSE	WW domain-containing adapter protein with coiled-coil	11827461	WAC, a novel WW domain-containing adapter with a coiled-coil region, is colocalized with splicing factor SC35.

P33317	DUT_YEAST	Deoxyuridine 5'-triphosphate nucleotidohydrolase	8223452	dUTP pyrophosphatase is an essential enzyme in Saccharomyces cerevisiae.

O75154	RFIP3_HUMAN	Rab11 family-interacting protein 3	17394487	Rab11-FIP3 is critical for the structural integrity of the endosomal recycling compartment.

O14114	YEJJ_SCHPO	Uncharacterized AAA domain-containing protein C31G5.19	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O75487	GPC4_HUMAN	Glypican-4	9787072	GPC4, the gene for human K-glypican, flanks GPC3 on Xq26: deletion of the GPC3-GPC4 gene cluster in one family with Simpson-Golabi-Behmel syndrome.

O13734	SGO2_SCHPO	Shugoshin-2	14730319	The conserved kinetochore protein shugoshin protects centromeric cohesion during meiosis.

Q8BGW8	VGLL2_MOUSE	Transcription cofactor vestigial-like protein 2	12376544	Mammalian vestigial-like 2, a cofactor of TEF-1 and MEF2 transcription factors that promotes skeletal muscle differentiation.

P56965	DDAH1_BOVIN	N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	12441345	Zn(II)-free dimethylargininase-1 (DDAH-1) is inhibited upon specific CysS-nitrosylation.

Q7TS99	HELT_MOUSE	Hairy and enhancer of split-related protein HELT	16644143	Molecular characterization, structure and developmental expression of Megane bHLH factor.

Q5Q995	KTAP2_IXOSC	Protein KRTCAP2 homolog	16431279	An annotated catalog of salivary gland transcripts from Ixodes scapularis ticks.

P50238	CRIP1_HUMAN	Cysteine-rich protein 1	9126610	Human cysteine-rich intestinal protein: cDNA cloning and expression of recombinant protein and identification in human peripheral blood mononuclear cells.

B7ZQJ9	GT2D1_XENLA	General transcription factor II-I repeat domain-containing protein 1	16055724	Positive and negative regulation of the transforming growth factor beta/activin target gene goosecoid by the TFII-I family of transcription factors.

P47031	IML2_YEAST	Mitochondrial outer membrane protein IML2	16407407	Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins.

Q03920	MTQ2_YEAST	eRF1 methyltransferase catalytic subunit MTQ2	14562095	Global analysis of protein localization in budding yeast.

Q24141	SGO1_DROME	Shugoshin	7585942	Mei-S332, a Drosophila protein required for sister-chromatid cohesion, can localize to meiotic centromere regions.

Q8BGW1	FTO_MOUSE	Alpha-ketoglutarate-dependent dioxygenase FTO	18775698	Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO.

Q01448	HPC2_YEAST	Histone promoter control protein 2	16303565	Replication-independent histone deposition by the HIR complex and Asf1.

P40955	CHS6_YEAST	Chitin biosynthesis protein CHS6	14562095	Global analysis of protein localization in budding yeast.

P97470	PP4C_MOUSE	Serine/threonine-protein phosphatase 4 catalytic subunit	18715871	PP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4.

Q9H295	TM7S4_HUMAN	Transmembrane 7 superfamily member 4	11169400	DC-STAMP, a novel multimembrane-spanning molecule preferentially expressed by dendritic cells.

Q06680	CND3_YEAST	Condensin complex subunit 3	10811823	The condensin complex governs chromosome condensation and mitotic transmission of rDNA.

Q56XE8	HXK4_ARATH	Hexokinase-4	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q9M9M4	CSLD3_ARATH	Cellulose synthase-like protein D3	11156607	KOJAK encodes a cellulose synthase-like protein required for root hair cell morphogenesis in Arabidopsis.

Q98TT6	4EB3L_DANRE	Eukaryotic translation initiation factor 4E-binding protein 3-like	14701818	Two zebrafish eIF4E family members are differentially expressed and functionally divergent.

O54835	SMAD9_RAT	Mothers against decapentaplegic homolog 9	9371779	Smad8 mediates the signaling of the ALK-2 receptor serine kinase.

P16471	PRLR_HUMAN	Prolactin receptor	2558309	Identification of a cDNA encoding a long form of prolactin receptor in human hepatoma and breast cancer cells.

P84816	AGSP1_LEPFX	Aggression-stimulating peptide	15752573	Characterization of a peptide from skin secretions of male specimens of the frog, Leptodactylus fallax that stimulates aggression in male frogs.

Q9P2W9	STX18_HUMAN	Syntaxin-18	15272311	Involvement of BNIP1 in apoptosis and endoplasmic reticulum membrane fusion.

Q8JFZ2	GSTP1_XENLA	Glutathione S-transferase P 1	12710888	A novel amphibian Pi-class glutathione transferase isoenzyme from Xenopus laevis: importance of phenylalanine 111 in the H-site.

Q99KJ8	DCTN2_MOUSE	Dynactin subunit 2	9144527	The presence of the 50-kDa subunit of dynactin complex in the nerve growth cone.

Q94JQ6	CESA6_ARATH	Cellulose synthase A catalytic subunit 6 [UDP-forming]	11842152	Resistance against herbicide isoxaben and cellulose deficiency caused by distinct mutations in same cellulose synthase isoform CESA6.

P55285	CADH6_HUMAN	Cadherin-6	7743525	Isolation and sequence analysis of human cadherin-6 complementary DNA for the full coding sequence and its expression in human carcinoma cells.

O43829	ZF161_HUMAN	Zinc finger protein 161 homolog	9177479	Expression cloning and intracellular localization of a human ZF5 homologue.

Q6U841	S4A10_HUMAN	Sodium-driven chloride bicarbonate exchanger	10993873	The Na+-driven Cl-/HCO3- exchanger. Cloning, tissue distribution, and functional characterization.

Q6MZN7	HCP5_HUMAN	HLA class I histocompatibility antigen protein P5	8462994	A novel coding sequence belonging to a new multicopy gene family mapping within the human MHC class I region.

O59677	RT23_SCHPO	37S ribosomal protein S23, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q92904	DAZL_HUMAN	Deleted in azoospermia-like	8968755	A SPGY copy homologous to the mouse gene Dazla and the Drosophila gene boule is autosomal and expressed only in the human male gonad.

P49657	MNB_DROME	Serine/threonine-protein kinase minibrain	7857639	Minibrain: a new protein kinase family involved in postembryonic neurogenesis in Drosophila.

P22146	GAS1_YEAST	1,3-beta-glucanosyltransferase GAS1	15355340	Characterization of recombinant forms of the yeast Gas1 protein and identification of residues essential for glucanosyltransferase activity and folding.

Q9MBA3	RAD17_ARATH	Cell cycle checkpoint protein RAD17	15165187	The Rad17 homologue of Arabidopsis is involved in the regulation of DNA damage repair and homologous recombination.

Q9VWE0	DOME_DROME	Cytokine receptor	11696329	Identification of the first invertebrate interleukin JAK/STAT receptor, the Drosophila gene domeless.

Q9UKY1	ZHX1_HUMAN	Zinc fingers and homeoboxes protein 1	12237128	Functional analysis and the molecular dissection of zinc-fingers and homeoboxes 1 (ZHX1).

P33413	DUR3_YEAST	Urea active transporter	8335627	Regulation of the urea active transporter gene (DUR3) in Saccharomyces cerevisiae.

Q91VN1	ZNF24_MOUSE	Zinc finger protein 24	18685786	Characterization of the target DNA sequence for the DNA-binding domain of zinc finger protein 191.

P53384	NUBP1_HUMAN	Cytosolic Fe-S cluster assembly factor NUBP1	7926816	Cloning of a human cDNA encoding a putative nucleotide-binding protein related to Escherichia coli MinD.

O64654	TRL11_ARATH	Thioredoxin-like 1-1, chloroplastic	19109414	A small family of chloroplast atypical thioredoxins.

P43585	VTC2_YEAST	Vacuolar transporter chaperone 2	11102525	New components of a system for phosphate accumulation and polyphosphate metabolism in Saccharomyces cerevisiae revealed by genomic expression analysis.

P82869	CYP37_ARATH	Peptidyl-prolyl cis-trans isomerase CYP37, chloroplastic	15322131	New functions of the thylakoid membrane proteome of Arabidopsis thaliana revealed by a simple, fast, and versatile fractionation strategy.

O15205	UBD_HUMAN	Ubiquitin D	9368598	Identification and analysis of a novel member of the ubiquitin family expressed in dendritic cells and mature B cells.

Q9HD40	SPCS_HUMAN	O-phosphoseryl-tRNA(Sec) selenium transferase	10801173	Identification of target antigen for SLA/LP autoantibodies in autoimmune hepatitis.

P32776	TFB1_YEAST	RNA polymerase II transcription factor B subunit 1	14500720	Revised subunit structure of yeast transcription factor IIH (TFIIH) and reconciliation with human TFIIH.

O59740	MOD5P_SCHPO	Cell polarity protein mod5	16222337	Multistep and multimode cortical anchoring of tea1p at cell tips in fission yeast.

P38281	APD1_YEAST	Actin patches distal protein 1	14562095	Global analysis of protein localization in budding yeast.

Q9WU01	KHDR2_MOUSE	KH domain-containing, RNA-binding, signal transduction-associated protein 2	10077576	Characterization of Sam68-like mammalian proteins SLM-1 and SLM-2: SLM-1 is a Src substrate during mitosis.

P59224	RS132_ARATH	40S ribosomal protein S13-2	10849343	Disruption of an Arabidopsis cytoplasmic ribosomal protein S13- homologous gene by transposon-mediated mutagenesis causes aberrant growth and development.

Q9FLG1	BXL4_ARATH	Beta-D-xylosidase 4	15181203	Purification and characterization of enzymes exhibiting beta-D- xylosidase activities in stem tissues of Arabidopsis.

Q9JKX4	AATF_MOUSE	Protein AATF	11071758	The murine gene, Traube, is essential for the growth of preimplantation embryos.

P36046	MIA40_YEAST	Mitochondrial intermembrane space import and assembly protein 40	15989955	A disulfide relay system in the intermembrane space of mitochondria that mediates protein import.

O75448	MED24_HUMAN	Mediator of RNA polymerase II transcription subunit 24	10235267	Composite co-activator ARC mediates chromatin-directed transcriptional activation.

P32501	EI2BE_YEAST	Translation initiation factor eIF-2B subunit epsilon	9472020	eIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine-nucleotide exchange.

Q99538	LGMN_HUMAN	Legumain	9065484	Cloning, isolation, and characterization of mammalian legumain, an asparaginyl endopeptidase.

O35608	ANGP2_MOUSE	Angiopoietin-2	9204896	Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis.

Q07534	S2538_YEAST	Solute carrier family 25 member 38 homolog	19412178	Mutations in mitochondrial carrier family gene SLC25A38 cause nonsyndromic autosomal recessive congenital sideroblastic anemia.

P10961	HSF_YEAST	Heat shock factor protein	3044612	Isolation of the gene encoding the S. cerevisiae heat shock transcription factor.

P0A9Q9	DHAS_ECOLI	Aspartate-semialdehyde dehydrogenase	14726201	L-cystine inhibits aspartate-beta-semialdehyde dehydrogenase by covalently binding to the essential 135Cys of the enzyme.

Q09685	DRE4_SCHPO	DNA replication protein 4	15466421	A screen for Schizosaccharomyces pombe mutants defective in rereplication identifies new alleles of rad4+, cut9+ and psf2+.

O74304	WIN1_SCHPO	MAP kinase kinase kinase win1	15936270	Wsh3/Tea4 is a novel cell-end factor essential for bipolar distribution of Tea1 and protects cell polarity under environmental stress in S. pombe.

Q9UKT6	FXL21_HUMAN	F-box/LRR-repeat protein 21	10531035	Identification of a family of human F-box proteins.

Q12860	CNTN1_HUMAN	Contactin-1	7959734	Molecular cloning and in situ localization of the human contactin gene (CNTN1) on chromosome 12q11-q12.

O35427	RPC9_MOUSE	DNA-directed RNA polymerase III subunit RPC9	10067875	Testes exhibit elevated expression of calcitonin gene-related peptide receptor component protein.

Q09176	U2AF1_SCHPO	Splicing factor U2AF 23 kDa subunit	8657565	The small subunit of the splicing factor U2AF is conserved in fission yeast.

P47998	CYSK1_ARATH	Cysteine synthase	10940562	Genomic and functional characterization of the oas gene family encoding O-acetylserine (thiol) lyases, enzymes catalyzing the final step in cysteine biosynthesis in Arabidopsis thaliana.

P43007	SATT_HUMAN	Neutral amino acid transporter A	8340364	Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/glutamate cotransporters.

Q01081	U2AF1_HUMAN	Splicing factor U2AF 35 kDa subunit	1388271	Cloning and intracellular localization of the U2 small nuclear ribonucleoprotein auxiliary factor small subunit.

P35813	PPM1A_HUMAN	Protein phosphatase 1A	1311954	Mammalian protein serine/threonine phosphatase 2C: cDNA cloning and comparative analysis of amino acid sequences.

Q16539	MK14_HUMAN	Mitogen-activated protein kinase 14	7997261	A protein kinase involved in the regulation of inflammatory cytokine biosynthesis.

Q9QZB7	ARP10_MOUSE	Actin-related protein 10	10525537	Analysis of dynactin subcomplexes reveals a novel actin-related protein associated with the Arp1 minifilament pointed end.

Q9QY53	NPHP1_MOUSE	Nephrocystin-1	10739664	Crk-associated substrate p130(Cas) interacts with nephrocystin and both proteins localize to cell-cell contacts of polarized epithelial cells.

P11938	RAP1_YEAST	DNA-binding protein RAP1	8508768	GCR1, a transcriptional activator in Saccharomyces cerevisiae, complexes with RAP1 and can function without its DNA binding domain.

Q9D304	RN128_MOUSE	E3 ubiquitin-protein ligase RNF128	12705856	GRAIL: an E3 ubiquitin ligase that inhibits cytokine gene transcription is expressed in anergic CD4+ T cells.

Q8NCG5	CHST4_HUMAN	Carbohydrate sulfotransferase 4	12855678	Golgi localization of carbohydrate sulfotransferases is a determinant of L-selectin ligand biosynthesis.

P40967	PME17_HUMAN	Melanocyte protein Pmel 17	15695812	MART-1 is required for the function of the melanosomal matrix protein PMEL17/GP100 and the maturation of melanosomes.

P37235	HPCL1_HUMAN	Hippocalcin-like protein 1	8038222	Molecular cloning of a novel calcium-binding protein structurally related to hippocalcin from human brain and chromosomal mapping of its gene.

Q6NS57	MABP1_MOUSE	Mitogen-activated protein kinase-binding protein 1	10471813	A novel Jun N-terminal kinase (JNK)-binding protein that enhances the activation of JNK by MEK kinase 1 and TGF-beta-activated kinase 1.

P46965	SPC1_YEAST	Signal peptidase complex subunit SPC1	8663399	The homologue of mammalian SPC12 is important for efficient signal peptidase activity in Saccharomyces cerevisiae.

Q9D9X6	ZSWM2_MOUSE	E3 ubiquitin-protein ligase Zswim2	16522193	MEX is a testis-specific E3 ubiquitin ligase that promotes death receptor-induced apoptosis.

O60952	LIME_DICDI	LIM domain-containing protein E	9487125	DdLIM is a cytoskeleton-associated protein involved in the protrusion of lamellipodia in Dictyostelium.

Q9BVN2	RUSC1_HUMAN	RUN and SH3 domain-containing protein 1	10760598	Molecular cloning and characterization of a novel human gene (NESCA) which encodes a putative adapter protein containing SH3.

P08912	ACM5_HUMAN	Muscarinic acetylcholine receptor M5	3272174	Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes.

P26306	RAD9_SCHPO	DNA repair protein rad9	8536960	Extragenic suppressors of Schizosaccharomyces pombe rad9 mutations uncouple radioresistance and hydroxyurea sensitivity from cell cycle checkpoint control.

Q9NBK5	TRC_DROME	Serine/threonine-protein kinase tricorner	15975907	Drosophila Mob family proteins interact with the related tricornered (Trc) and warts (Wts) kinases.

P34709	TRA2_CAEEL	Sex-determining transformer protein 2	11250902	The TRA-1 transcription factor binds TRA-2 to regulate sexual fates in Caenorhabditis elegans.

Q920B0	FRM4B_MOUSE	FERM domain-containing protein 4B	11445584	Signaling complexes of the FERM domain-containing protein GRSP1 bound to ARF exchange factor GRP1.

P83865	H4_LITVA	Histone H4	15606770	Antimicrobial activity of histones from hemocytes of the Pacific white shrimp.

Q03691	ROT1_YEAST	Protein ROT1	16874095	Causal links between protein folding in the ER and events along the secretory pathway.

O14920	IKKB_HUMAN	Inhibitor of nuclear factor kappa-B kinase subunit beta	9346485	IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK.

P10911	MCF2_HUMAN	Proto-oncogene DBL	3056717	Molecular cloning and characterization of the human dbl proto- oncogene: evidence that its overexpression is sufficient to transform NIH/3T3 cells.

Q8NHX4	SPTA3_HUMAN	Spermatogenesis-associated protein 3	12812072	Molecular cloning for testis spermatogenesis cell apoptosis related gene TSARG1 and Mtsarg1 and expression analysis for Mtsarg1 gene.

Q9H190	SDCB2_HUMAN	Syntenin-2	11152476	The neural cell recognition molecule neurofascin interacts with syntenin-1 but not with syntenin-2, both of which reveal self- associating activity.

P41003	SMC2_SCHPO	Structural maintenance of chromosomes protein 2	7957061	Fission yeast cut3 and cut14, members of a ubiquitous protein family, are required for chromosome condensation and segregation in mitosis.

Q02732	CTF19_YEAST	Central kinetochore subunit CTF19	11782448	Ctf3p, the Mis6 budding yeast homolog, interacts with Mcm22p and Mcm16p at the yeast outer kinetochore.

O54889	RPA1_RAT	DNA-directed RNA polymerase I subunit RPA1	9422795	Affinity purification of mammalian RNA polymerase I. Identification of an associated kinase.

P0CE72	ONCO_HUMAN	Oncomodulin-1	8354278	Human alpha and beta parvalbumins. Structure and tissue-specific expression.

O75971	SNPC5_HUMAN	snRNA-activating protein complex subunit 5	9732265	SNAP19 mediates the assembly of a functional core promoter complex (SNAPc) shared by RNA polymerases II and III.

Q99MD6	TRXR3_MOUSE	Thioredoxin reductase 3	11259642	Selenoprotein oxidoreductase with specificity for thioredoxin and glutathione systems.

P28188	RBD2A_ARATH	Ras-related protein RABD2A	11090219	A rab1 GTPase is required for transport between the endoplasmic reticulum and golgi apparatus and for normal golgi movement in plants.

Q99558	M3K14_HUMAN	Mitogen-activated protein kinase kinase kinase 14	12874243	Pellino3, a novel member of the Pellino protein family, promotes activation of c-Jun and Elk-1 and may act as a scaffolding protein.

P21240	RUBB_ARATH	RuBisCO large subunit-binding protein subunit beta, chloroplastic	1347275	Isolation and characterization of genes encoding chaperonin 60 beta from Arabidopsis thaliana.

Q13547	HDAC1_HUMAN	Histone deacetylase 1	12670868	Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell- proliferation factor HCF-1.

Q960N3	CORT_DROME	Protein cortex	11252055	Cortex, a Drosophila gene required to complete oocyte meiosis, is a member of the Cdc20/fizzy protein family.

Q9CAF5	AB6I_ARATH	ABC transporter I family member 6, chloroplastic	15184673	AtNAP7 is a plastidic SufC-like ATP-binding cassette/ATPase essential for Arabidopsis embryogenesis.

P20965	PABPA_XENLA	Polyadenylate-binding protein 1-A	11274061	A novel embryonic poly(A) binding protein, ePAB, regulates mRNA deadenylation in Xenopus egg extracts.

P05987	KAPR_DICDI	cAMP-dependent protein kinase regulatory subunit	1312226	Mutation of protein kinase A causes heterochronic development of Dictyostelium.

Q92585	MAML1_HUMAN	Mastermind-like protein 1	15546612	Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover.

P43694	GATA4_HUMAN	Transcription factor GATA-4	12845333	GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5.

P14616	INSRR_HUMAN	Insulin receptor-related protein	10226785	Cloning and sequencing of the complete cDNA encoding the human insulin receptor related receptor.

Q78IQ7	S39A4_MOUSE	Zinc transporter ZIP4	14612438	Zn2+-stimulated endocytosis of the mZIP4 zinc transporter regulates its location at the plasma membrane.

Q96GM5	SMRD1_HUMAN	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1	12917342	BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation.

Q61006	MUSK_MOUSE	Muscle, skeletal receptor tyrosine-protein kinase	17576800	Regulation of synaptic growth and maturation by a synapse-associated E3 ubiquitin ligase at the neuromuscular junction.

Q63744	RHG07_RAT	Rho GTPase-activating protein 7	7835339	A dual functional signal mediator showing RhoGAP and phospholipase C- delta stimulating activities.

Q16778	H2B2E_HUMAN	Histone H2B type 2-E	1469070	A human histone H2B.1 variant gene, located on chromosome 1, utilizes alternative 3' end processing.

P18113	THB_RAT	Thyroid hormone receptor beta	2457590	Isolation and characterization of rat cDNA clones for two distinct thyroid hormone receptors.

O15499	GSC2_HUMAN	Homeobox protein goosecoid-2	9150167	The DiGeorge syndrome minimal critical region contains a goosecoid- like (GSCL) homeobox gene that is expressed early in human development.

Q9VJS8	ELBOW_DROME	Zinc finger protein Elbow	14757638	Proximodistal subdivision of Drosophila legs and wings: the elbow-no ocelli gene complex.

P38349	UBX7_YEAST	UBX domain-containing protein 7	15258615	Shp1 and Ubx2 are adaptors of Cdc48 involved in ubiquitin-dependent protein degradation.

Q99536	VAT1_HUMAN	Synaptic vesicle membrane protein VAT-1 homolog	8938427	Complete genomic sequence and analysis of 117 kb of human DNA containing the gene BRCA1.

P10862	RAD18_YEAST	Postreplication repair E3 ubiquitin-protein ligase RAD18	12226657	RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO.

P29453	RL8B_YEAST	60S ribosomal protein L8-B	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

P83245	RIP_PLETU	Ribosome-inactivating protein pleuturegin	11676502	Isolation of pleuturegin, a novel ribosome-inactivating protein from fresh sclerotia of the edible mushroom Pleurotus tuber-regium.

Q8CIV7	OVOL2_MOUSE	Transcription factor Ovo-like 2	15225875	Characterization of the isoforms of MOVO zinc finger protein, a mouse homologue of Drosophila Ovo, as a transcription factors.

Q63245	FOXD3_RAT	Forkhead box protein D3	7683413	Identification of nine tissue-specific transcription factors of the hepatocyte nuclear factor 3/forkhead DNA-binding-domain family.

Q9QY16	DDX25_RAT	ATP-dependent RNA helicase DDX25	16968703	Gonadotropin-regulated testicular RNA helicase (GRTH/Ddx25) is a transport protein involved in gene-specific mRNA export and protein translation during spermatogenesis.

Q05728	PUR5_ARATH	Phosphoribosylformylglycinamidine cyclo-ligase, chloroplastic	8108507	Isolating the Arabidopsis thaliana genes for de novo purine synthesis by suppression of Escherichia coli mutants. I. 5'-Phosphoribosyl-5- aminoimidazole synthetase.

Q9SF23	FOLB1_ARATH	Dihydroneopterin aldolase	15165863	Biosynthesis of tetrahydrofolate in plants: crystal structure of 7,8- dihydroneopterin aldolase from Arabidopsis thaliana reveals a novel adolase class.

Q96P20	NALP3_HUMAN	NACHT, LRR and PYD domains-containing protein 3	12032915	Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes.

Q7Z2C4	SELG_DROME	Glycine-rich selenoprotein	16920070	G-rich, a Drosophila selenoprotein, is a Golgi-resident type III membrane protein.

Q9UBN7	HDAC6_HUMAN	Histone deacetylase 6	11948178	Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family.

Q8LG88	TDT_ARATH	Tonoplast dicarboxylate transporter	12947042	The plant homolog to the human sodium/dicarboxylic cotransporter is the vacuolar malate carrier.

P83011	13KDA_SCYCA	13.2 kDa protein	11676495	N-terminal sequences of small ion channels in rectal glands of sharks: a biochemical hallmark for classification and phylogeny?

Q6UJY2	S9A10_MOUSE	Sodium/hydrogen exchanger 10	14634667	A new sperm-specific Na+/H+ exchanger required for sperm motility and fertility.

P35918	VGFR2_MOUSE	Vascular endothelial growth factor receptor 2	8356051	Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium.

Q8TDM6	DLG5_HUMAN	Disks large homolog 5	9738934	Identification of a novel human homolog of the Drosophila dlg, P-dlg, specifically expressed in the gland tissues and interacting with p55.

Q13114	TRAF3_HUMAN	TNF receptor-associated factor 3	11035039	The ectodermal dysplasia receptor activates the nuclear factor- kappaB, JNK, and cell death pathways and binds to ectodysplasin A.

P31629	ZEP2_HUMAN	Transcription factor HIVEP2	2247438	Two genes encode factors with NF-kappa B- and H2TF1-like DNA-binding properties.

Q06200	ECM7_YEAST	Protein ECM7	9335584	Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae.

P41318	LST8_YEAST	Target of rapamycin complex subunit LST8	12631735	Tor kinases are in distinct membrane-associated protein complexes in Saccharomyces cerevisiae.

O93507	TAL1_DANRE	T-cell acute lymphocytic leukemia protein 1 homolog	14602685	Lmo2 and Scl/Tal1 convert non-axial mesoderm into haemangioblasts which differentiate into endothelial cells in the absence of Gata1.

P50298	ARY2_RAT	Arylamine N-acetyltransferase 2	7882993	Complementary DNAs for two arylamine N-acetyltransferases with identical 5' non-coding regions from rat pineal gland.

Q00PI9	HNRL2_MOUSE	Heterogeneous nuclear ribonucleoprotein U-like protein 2	17008314	Myeloid leukemia factor 1 associates with a novel heterogeneous nuclear ribonucleoprotein U-like molecule.

P00445	SODC_YEAST	Superoxide dismutase [Cu-Zn]	11500508	A fraction of yeast Cu,Zn-superoxide dismutase and its metallochaperone, CCS, localize to the intermembrane space of mitochondria. A physiological role for SOD1 in guarding against mitochondrial oxidative damage.

O70263	LNX1_MOUSE	E3 ubiquitin-protein ligase LNX	9535908	The mammalian numb phosphotyrosine-binding domain. Characterization of binding specificity and identification of a novel PDZ domain- containing numb binding protein, LNX.

Q9LKW9	NHX7_ARATH	Sodium/hydrogen exchanger 7	11884687	The putative plasma membrane Na(+)/H(+) antiporter SOS1 controls long-distance Na(+) transport in plants.

Q9XUJ7	DKF1_CAEEL	Serine/threonine-protein kinase dkf-1	16613841	Characterization of a novel protein kinase D: Caenorhabditis elegans DKF-1 is activated by translocation-phosphorylation and regulates movement and growth in vivo.

O75787	RENR_HUMAN	Renin receptor	15746149	A unique exonic splice enhancer mutation in a family with X-linked mental retardation and epilepsy points to a novel role of the renin receptor.

P40160	RIO2_YEAST	Serine/threonine-protein kinase RIO2	12612080	Late cytoplasmic maturation of the small ribosomal subunit requires RIO proteins in Saccharomyces cerevisiae.

P83316	FAR1_PENMO	FMRFamide-like neuropeptide FLP1	11959015	Seven novel FMRFamide-like neuropeptide sequences from the eyestalk of the giant tiger prawn Penaeus monodon.

Q9UTF7	ELOH1_SCHPO	Putative elongation of fatty acids protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q80Z30	PPM1E_RAT	Protein phosphatase 1E	12807427	Subcellular distributions of rat CaM kinase phosphatase N and other members of the CaM kinase regulatory system.

Q53H80	AKIR2_HUMAN	Akirin-2	18066067	Akirins are highly conserved nuclear proteins required for NF-kappaB- dependent gene expression in Drosophila and mice.

P97629	LCAP_RAT	Leucyl-cystinyl aminopeptidase	7559527	Cloning and characterization of a novel insulin-regulated membrane aminopeptidase from Glut4 vesicles.

Q9QYE0	PLAG1_MOUSE	Zinc finger protein PLAG1	15606491	Targeted disruption of the murine Plag1 proto-oncogene causes growth retardation and reduced fertility.

Q8VC66	ADIP_MOUSE	Afadin- and alpha-actinin-binding protein	12446711	ADIP, a novel afadin- and alpha-actinin-binding protein localized at cell-cell adherens junctions.

O93507	TAL1_DANRE	T-cell acute lymphocytic leukemia protein 1 homolog	17472439	Distinct functions for different scl isoforms in zebrafish primitive and definitive hematopoiesis.

Q12083	MLH3_YEAST	DNA mismatch repair protein MLH3	9770499	The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutations.

Q9NQX7	ITM2C_HUMAN	Integral membrane protein 2C	19366692	BRI3 inhibits amyloid precursor protein processing in a mechanistically distinct manner from its homologue dementia gene BRI2.

P61024	CKS1_HUMAN	Cyclin-dependent kinases regulatory subunit 1	2227411	Human cDNAs encoding homologs of the small p34Cdc28/Cdc2-associated protein of Saccharomyces cerevisiae and Schizosaccharomyces pombe.

P55008	AIF1_HUMAN	Allograft inflammatory factor 1	8912632	cDNA cloning of human allograft inflammatory factor-1: tissue distribution, cytokine induction, and mRNA expression in injured rat carotid arteries.

Q9WV78	PLVAP_RAT	Plasmalemma vesicle-associated protein	10366592	Isolation, cloning, and localization of rat PV-1, a novel endothelial caveolar protein.

Q12149	RRP6_YEAST	Exosome complex exonuclease RRP6	9582370	Rrp6p, the yeast homologue of the human PM-Scl 100-kDa autoantigen, is essential for efficient 5.8 S rRNA 3' end formation.

Q8BH60	GOPC_MOUSE	Golgi-associated PDZ and coiled-coil motif-containing protein	11162552	PIST: a novel PDZ/coiled-coil domain binding partner for the rho- family GTPase TC10.

O44572	TNNI4_CAEEL	Troponin I 4	15743415	Tissue expression of four troponin I genes and their molecular interactions with two troponin C isoforms in Caenorhabditis elegans.

P34092	MYOB_DICDI	Myosin IB heavy chain	16415352	Identification and characterization of an 8-kDa light chain associated with Dictyostelium discoideum MyoB, a class I myosin.

P61887	RMLA2_ECOLI	Glucose-1-phosphate thymidylyltransferase 2	12171937	Crystal structure of Escherichia coli glucose-1-phosphate thymidylyltransferase (RffH) complexed with dTTP and Mg2+.

Q7TQA5	T2R39_MOUSE	Taste receptor type 2 member 39	12734386	Evolutionary relationships of the Tas2r receptor gene families in mouse and human.

O73682	VGFAA_DANRE	Vascular endothelial growth factor A-A	11578859	The role of vascular endothelial growth factor (VEGF) in vasculogenesis, angiogenesis, and hematopoiesis in zebrafish development.

Q9V3T9	ADRO_DROME	NADPH:adrenodoxin oxidoreductase, mitochondrial	10498693	The dare gene: steroid hormone production, olfactory behavior, and neural degeneration in Drosophila.

P30560	V1AR_RAT	Vasopressin V1a receptor	1560825	Molecular cloning and expression of a rat V1a arginine vasopressin receptor.

P47870	GBRB2_HUMAN	Gamma-aminobutyric acid receptor subunit beta-2	8264558	Role of the beta subunit in determining the pharmacology of human gamma-aminobutyric acid type A receptors.

Q5VQG4	RFS_ORYSJ	Galactinol--sucrose galactosyltransferase	17206375	Characterization of raffinose synthase from rice (Oryza sativa L. var. Nipponbare).

Q05926	YL364_YEAST	Glutaredoxin-like protein YLR364W	14562095	Global analysis of protein localization in budding yeast.

O04292	ATBH9_ARATH	Homeobox-leucine zipper protein ATHB-9	17376809	The AP2 transcription factors DORNROSCHEN and DORNROSCHEN-LIKE redundantly control Arabidopsis embryo patterning via interaction with PHAVOLUTA.

Q99489	OXDD_HUMAN	D-aspartate oxidase	9163533	Structural and functional characterization of the human brain D- aspartate oxidase.

P12945	NAT1_YEAST	N-terminal acetyltransferase A complex subunit NAT1	1600941	ARD1 and NAT1 proteins form a complex that has N-terminal acetyltransferase activity.

P28347	TEAD1_HUMAN	Transcriptional enhancer factor TEF-1	18579750	TEAD mediates YAP-dependent gene induction and growth control.

P49771	FLT3L_HUMAN	SL cytokine	8145851	Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of haematopoietic stem cells and is encoded by variant RNAs.

Q02505	MUC3A_HUMAN	Mucin-3A	10405327	The MUC3 gene encodes a transmembrane mucin and is alternatively spliced.

Q5VWG9	TAF3_HUMAN	Transcription initiation factor TFIID subunit 3	11438666	The TFIID components human TAFII140 and Drosophila BIP2 (TAFII155) are novel metazoan homologues of yeast TAFII47 containing a histone fold and a PHD finger.

Q8N720	ZN655_HUMAN	Zinc finger protein 655	15558030	Characterization of VIK-1: a new Vav-interacting Kruppel-like protein.

Q06089	YP098_YEAST	Uncharacterized mitochondrial outer membrane protein YPR098C	14562095	Global analysis of protein localization in budding yeast.

Q08109	HRD1_YEAST	ERAD-associated E3 ubiquitin-protein ligase HRD1	9437001	Der3p/Hrd1p is required for endoplasmic reticulum-associated degradation of misfolded lumenal and integral membrane proteins.

Q8K202	RPA49_MOUSE	DNA-directed RNA polymerase I subunit RPA49	15226435	Multiple protein-protein interactions by RNA polymerase I-associated factor PAF49 and role of PAF49 in rRNA transcription.

Q14028	CNGB1_HUMAN	Cyclic nucleotide-gated cation channel beta-1	7682292	A new subunit of the cyclic nucleotide-gated cation channel in retinal rods.

Q9ES21	SAC1_RAT	Phosphatidylinositide phosphatase SAC1	10887188	Functional characterization of a mammalian Sac1 and mutants exhibiting substrate-specific defects in phosphoinositide phosphatase activity.

P38418	LOX2_ARATH	Lipoxygenase 2, chloroplastic	18487634	Caterpillar saliva interferes with induced Arabidopsis thaliana defence responses via the systemic acquired resistance pathway.

P20676	NUP1_YEAST	Nucleoporin NUP1	2190694	The NUP1 gene encodes an essential component of the yeast nuclear pore complex.

Q4TU14	RHF1A_ARATH	E3 ubiquitin-protein ligase RHF1A	15644464	Functional analysis of the RING-type ubiquitin ligase family of Arabidopsis.

Q9HB96	FANCE_HUMAN	Fanconi anemia group E protein	12093742	FANCE: the link between Fanconi anaemia complex assembly and activity.

Q96EZ8	MCRS1_HUMAN	Microspherule protein 1	11948183	Essential role of the 58-kDa microspherule protein in the modulation of Daxx-dependent transcriptional repression as revealed by nucleolar sequestration.

Q8LGU7	RNZN_ARATH	Nuclear ribonuclease Z	12032089	Assigning a function to a conserved group of proteins: the tRNA 3' - processing enzymes.

Q9Y802	LSD1_SCHPO	Lysine-specific histone demethylase 1	17434129	S. pombe LSD1 homologs regulate heterochromatin propagation and euchromatic gene transcription.

Q9U6A0	NCKX_DROME	Sodium/potassium/calcium exchanger Nckx30C	10545508	Cloning and characterization of a potassium-dependent sodium/calcium exchanger in Drosophila.

P81919	OR46A_DROME	Odorant receptor 46a, isoform A	10458908	Identification of candidate Drosophila olfactory receptors from genomic DNA sequence.

P38703	LAG1_YEAST	Sphingosine N-acyltransferase LAG1	15692566	Lip1p: a novel subunit of acyl-CoA ceramide synthase.

O61643	INHB_DROME	Inhibin beta chain	9618266	Identification of a new member of transforming growth factor-beta superfamily in Drosophila: the first invertebrate activin gene.

P15178	SYDC_RAT	Aspartyl-tRNA synthetase, cytoplasmic	2642907	Molecular cloning and primary structure of cDNA encoding the catalytic domain of rat liver aspartyl-tRNA synthetase.

Q9WVS6	PRKN2_MOUSE	E3 ubiquitin-protein ligase parkin	11675120	Differential expression and tissue distribution of parkin isoforms during mouse development.

P47914	RL29_HUMAN	60S ribosomal protein L29	8662616	cDNA cloning and expression of HIP, a novel cell surface heparan sulfate/heparin-binding protein of human uterine epithelial cells and cell lines.

Q92466	DDB2_HUMAN	DNA damage-binding protein 2	12732143	The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage.

Q39189	RH7_ARATH	DEAD-box ATP-dependent RNA helicase 7	9121476	PRH 75, a new nuclear-localized member of the DEAD-box protein family from higher plants.

Q9Y6N7	ROBO1_HUMAN	Roundabout homolog 1	9458045	Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors.

Q9LY23	IPMKA_ARATH	Inositol polyphosphate multikinase alpha	12226109	Molecular and biochemical characterization of two plant inositol polyphosphate 6-/3-/5-kinases.

Q9N4H4	PME1_CAEEL	Poly(ADP-ribose) polymerase pme-1	12600937	Identification of genes that protect the C. elegans genome against mutations by genome-wide RNAi.

Q8IL06	YPF07_PLAF7	Uncharacterized protein PF14_0444	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

P32561	RPD3_YEAST	Histone deacetylase RPD3	10388812	A general requirement for the Sin3-Rpd3 histone deacetylase complex in regulating silencing in Saccharomyces cerevisiae.

Q3UNH4	GRIN1_MOUSE	G protein-regulated inducer of neurite outgrowth 1	10480904	A candidate target for G protein action in brain.

P41832	BNI1_YEAST	Protein BNI1	14561409	Formin leaky cap allows elongation in the presence of tight capping proteins.

O04019	PS6AB_ARATH	26S protease regulatory subunit 6A homolog B	19223514	The Arabidopsis proteasome RPT5 subunits are essential for gametophyte development and show accession-dependent redundancy.

Q9JKL1	PKR1_MOUSE	Prokineticin receptor 1	12024206	Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus.

Q9DG12	ARNT2_DANRE	Aryl hydrocarbon receptor nuclear translocator 2	11072074	Identification and expression of alternatively spliced aryl hydrocarbon nuclear translocator 2 (ARNT2) cDNAs from zebrafish with distinct functions.

O00767	ACOD_HUMAN	Acyl-CoA desaturase	10229681	Human stearoyl-CoA desaturase: alternative transcripts generated from a single gene by usage of tandem polyadenylation sites.

P45432	CSN1_ARATH	COP9 signalosome complex subunit 1	11854419	CSN1 N-terminal-dependent activity is required for Arabidopsis development but not for Rub1/Nedd8 deconjugation of cullins: a structure-function study of CSN1 subunit of COP9 signalosome.

Q9NQ94	A1CF_HUMAN	APOBEC1 complementation factor	12896982	A novel nuclear localization signal in the auxiliary domain of apobec-1 complementation factor regulates nucleocytoplasmic import and shuttling.

O95866	G6B_HUMAN	Protein G6b	11544253	G6b, a novel immunoglobulin superfamily member encoded in the human major histocompatibility complex, interacts with SHP-1 and SHP-2.

P15692	VEGFA_HUMAN	Vascular endothelial growth factor A	11427521	Vascular endothelial growth factor induces cyclooxygenase-dependent proliferation of endothelial cells via the VEGF-2 receptor.

Q9UTR7	MCP3_SCHPO	Meiotic coiled-coil protein 3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P09152	NARG_ECOLI	Respiratory nitrate reductase 1 alpha chain	3053688	Roles of the narJ and narI gene products in the expression of nitrate reductase in Escherichia coli.

P40793	CDC42_DROME	Cdc42 homolog	9371783	Genghis Khan (Gek) as a putative effector for Drosophila Cdc42 and regulator of actin polymerization.

O76090	BEST1_HUMAN	Bestrophin-1	19853238	Missense mutations in a retinal pigment epithelium protein, bestrophin-1, cause retinitis pigmentosa.

P21549	SPYA_HUMAN	Serine--pyruvate aminotransferase	1703535	Identification of mutations associated with peroxisome-to- mitochondrion mistargeting of alanine/glyoxylate aminotransferase in primary hyperoxaluria type 1.

Q03529	SCS7_YEAST	Ceramide very long chain fatty acid hydroxylase SCS7	9559540	Synthesis of monohydroxylated inositolphosphorylceramide (IPC-C) in Saccharomyces cerevisiae requires Scs7p, a protein with both a cytochrome b5-like domain and a hydroxylase/desaturase domain.

Q06738	LTI78_ARATH	Low-temperature-induced 78 kDa protein	8448363	Differential expression of two related, low-temperature-induced genes in Arabidopsis thaliana (L.) Heynh.

P00957	SYA_ECOLI	Alanyl-tRNA synthetase	18172502	Distinct domains of tRNA synthetase recognize the same base pair.

P70232	CHL1_MOUSE	Neural cell adhesion molecule L1-like protein	14659567	Mice deficient for the close homologue of the neural adhesion cell L1 (CHL1) display alterations in emotional reactivity and motor coordination.

Q4LCS8	TXA25_ANDAU	Beta-toxin AaBTxL1	15963953	New 'birtoxin analogs' from Androctonus australis venom.

P51158	RAB28_RAT	Ras-related protein Rab-28	8647132	Alternative mRNA splicing of the novel GTPase Rab28 generates isoforms with different C-termini.

Q96SZ6	CK5P1_HUMAN	CDK5 regulatory subunit-associated protein 1	11882646	Identification of a neuronal Cdk5 activator-binding protein as Cdk5 inhibitor.

P27637	BUD14_YEAST	Bud site selection protein 14	16107882	The Bud14p-Glc7p complex functions as a cortical regulator of dynein in budding yeast.

Q9N392	NARF_CAEEL	Probable cytosolic Fe-S cluster assembly factor oxy-4	19335616	[FeFe]-hydrogenase-like gene is involved in the regulation of sensitivity to oxygen in yeast and nematode.

Q9H668	STN1_HUMAN	CST complex subunit STN1	19854130	RPA-like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathway.

P09085	CAD_DROME	Homeotic protein caudal	9609826	Role of caudal in hindgut specification and gastrulation suggests homology between Drosophila amnioproctodeal invagination and vertebrate blastopore.

P0C5Y8	ALS2_RAT	Alsin	16802292	Alsin/Rac1 signaling controls survival and growth of spinal motoneurons.

Q00987	MDM2_HUMAN	E3 ubiquitin-protein ligase Mdm2	9450543	Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53.

Q08347	BDS1_YEAST	Alkyl/aryl-sulfatase BDS1	15947202	Contribution of horizontal gene transfer to the evolution of Saccharomyces cerevisiae.

Q8IN41	TOTX_DROME	Protein Turandot X	11409894	A family of Turandot-related genes in the humoral stress response of Drosophila.

P09874	PARP1_HUMAN	Poly [ADP-ribose] polymerase 1	17396150	A novel human AP endonuclease with conserved zinc-finger-like motifs involved in DNA strand break responses.

Q8WWW0	RASF5_HUMAN	Ras association domain-containing protein 5	15109305	Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras.

Q9XFB0	YAB2_ARATH	Putative axial regulator YABBY 2	10457020	Members of the YABBY gene family specify abaxial cell fate in Arabidopsis.

Q8CHW5	BICR2_MOUSE	Bicaudal D-related protein 2	20360680	Pericentrosomal targeting of Rab6 secretory vesicles by Bicaudal-D- related protein 1 (BICDR-1) regulates neuritogenesis.

Q9JJ11	TACC3_MOUSE	Transforming acidic coiled-coil-containing protein 3	17920017	Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool.

Q9UT08	2AAA_SCHPO	Protein phosphatase PP2A regulatory subunit A	9078365	The regulatory subunits of fission yeast protein phosphatase 2A (PP2A) affect cell morphogenesis, cell wall synthesis and cytokinesis.

P46010	NRL3_ARATH	Nitrilase 3	8022831	Differential regulation of an auxin-producing nitrilase gene family in Arabidopsis thaliana.

Q91VZ6	SMAP1_MOUSE	Stromal membrane-associated protein 1	9644265	Involvement of stromal membrane-associated protein (SMAP-1) in erythropoietic microenvironment.

P34687	COL34_CAEEL	Cuticle collagen 34	1398138	Sequence comparison of the Caenorhabditis elegans dpy-13 and col-34 genes, and their deduced collagen products.

P0ABP3	DCUC_ECOLI	Anaerobic C4-dicarboxylate transporter dcuC	8955408	Identification of a third secondary carrier (DcuC) for anaerobic C4- dicarboxylate transport in Escherichia coli: roles of the three Dcu carriers in uptake and exchange.

P40458	ATG32_YEAST	Autophagy-related protein 32	9335584	Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae.

O94710	PGP1_SCHPO	Glycoprotease pgp1, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P49597	P2C56_ARATH	Protein phosphatase 2C 56	16614222	A bifurcating pathway directs abscisic acid effects on stomatal closure and opening in Arabidopsis.

P62837	UB2D2_HUMAN	Ubiquitin-conjugating enzyme E2 D2	18703417	Ubiquitin-conjugating enzyme UBE2D2 is responsible for FBXW2 (F-box and WD repeat domain containing 2)-mediated human GCM1 (glial cell missing homolog 1) ubiquitination and degradation.

P25303	SCJ1_YEAST	DnaJ-related protein SCJ1	7744969	A yeast DnaJ homologue, Scj1p, can function in the endoplasmic reticulum with BiP/Kar2p via a conserved domain that specifies interactions with Hsp70s.

P20340	RAB6A_HUMAN	Ras-related protein Rab-6A	16332443	Structure of the extremely slow GTPase Rab6A in the GTP bound form at 1.8A resolution.

Q9UJ72	ANX10_HUMAN	Annexin A10	10458909	Novel human and mouse annexin A10 are linked to the genome duplications during early chordate evolution.

P40316	SECU_YEAST	Securin	9635435	An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast.

P27680	COQ3_YEAST	Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial	1885593	Ubiquinone biosynthesis in Saccharomyces cerevisiae. Isolation and sequence of COQ3, the 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase gene.

Q9NPJ3	ACO13_HUMAN	Acyl-coenzyme A thioesterase 13	16934754	Crystal structure of human thioesterase superfamily member 2.

Q13625	ASPP2_HUMAN	Apoptosis-stimulating of p53 protein 2	10498867	NF-kappaB subunit p65 binds to 53BP2 and inhibits cell death induced by 53BP2.

Q9U2Q9	GSK3_CAEEL	Glycogen synthase kinase-3	16251270	Regulation of the Caenorhabditis elegans oxidative stress defense protein SKN-1 by glycogen synthase kinase-3.

O13615	PRP46_SCHPO	Pre-mRNA-splicing factor prp46	9745017	Cell-division-cycle defects associated with fission yeast pre-mRNA splicing mutants.

Q62193	RFA2_MOUSE	Replication protein A 32 kDa subunit	1908076	cDNA cloning of the murine 30-kDa protein homologous to the 32-kDa subunit of human replication protein A.

Q9UHB6	LIMA1_HUMAN	LIM domain and actin-binding protein 1	12566430	EPLIN regulates actin dynamics by cross-linking and stabilizing filaments.

Q02939	TFB2_YEAST	RNA polymerase II transcription factor B subunit 2	9235928	Genes for Tfb2, Tfb3, and Tfb4 subunits of yeast transcription/repair factor IIH. Homology to human cyclin-dependent kinase activating kinase and IIH subunits.

Q06493	YLH47_YEAST	LETM1 domain-containing protein YLH47, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

O42996	YBC5_SCHPO	Uncharacterized WD repeat-containing protein C27B12.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P0AEG6	DSBC_ECOLI	Thiol:disulfide interchange protein DsbC	8168498	The Escherichia coli dsbC (xprA) gene encodes a periplasmic protein involved in disulfide bond formation.

P27859	TATD_ECOLI	Deoxyribonuclease tatD	10747959	TatD is a cytoplasmic protein with DNase activity. No requirement for TatD family proteins in sec-independent protein export.

P83292	G23AB_DROME	Putative gustatory receptor 23a, isoform B	10710312	Candidate taste receptors in Drosophila.

P53121	FLC3_YEAST	Putative flavin carrier protein 3	16717099	A screen for genes of heme uptake identifies the FLC family required for import of FAD into the endoplasmic reticulum.

P0A752	NADD_ECOLI	Nicotinate-nucleotide adenylyltransferase	10894752	Identification of the Escherichia coli nicotinic acid mononucleotide adenylyltransferase gene.

O00512	BCL9_HUMAN	B-cell CLL/lymphoma 9 protein	11955446	Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex.

Q9LYN0	PR1B1_ARATH	PRA1 family protein B1	18583532	The PRA1 gene family in Arabidopsis.

P06133	UD2B4_HUMAN	UDP-glucuronosyltransferase 2B4	8333863	cDNA cloning and expression of two new members of the human liver UDP-glucuronosyltransferase 2B subfamily.

Q67ZE1	HSDD2_ARATH	3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2	16835224	Molecular and enzymatic characterizations of novel bifunctional 3beta-hydroxysteroid dehydrogenases/C-4 decarboxylases from Arabidopsis thaliana.

P41562	IDHC_RAT	Isocitrate dehydrogenase [NADP] cytoplasmic	8083215	Cytosolic NADP(+)-dependent isocitrate dehydrogenase. Isolation of rat cDNA and study of tissue-specific and developmental expression of mRNA.

P62312	LSM6_HUMAN	U6 snRNA-associated Sm-like protein LSm6	10523320	A doughnut-shaped heteromer of human Sm-like proteins binds to the 3'-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro.

Q8CDG1	PIWL2_MOUSE	Piwi-like protein 2	14736746	Mili, a mammalian member of piwi family gene, is essential for spermatogenesis.

Q8VZS8	PYL1_ARATH	Abscisic acid receptor PYL1	19898420	A gate-latch-lock mechanism for hormone signalling by abscisic acid receptors.

O94668	NSE5_SCHPO	Non-structural maintenance of chromosome element 5	16478984	The Nse5-Nse6 dimer mediates DNA repair roles of the Smc5-Smc6 complex.

Q15722	LT4R1_HUMAN	Leukotriene B4 receptor 1	9177352	A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis.

P10124	SRGN_HUMAN	Serglycin	15136585	Localization of serglycin in human neutrophil granulocytes and their precursors.

Q62745	CD81_RAT	CD81 antigen	8757260	Astrocyte growth, reactivity, and the target of the antiproliferative antibody, TAPA.

Q62795	NPT1_RAT	Sodium-dependent phosphate transport protein 1	8867793	Molecular cloning of two rat Na+/Pi cotransporters: evidence for differential tissue expression of transcripts.

O43264	ZW10_HUMAN	Centromere/kinetochore protein zw10 homolog	15824131	ZW10 links mitotic checkpoint signaling to the structural kinetochore.

P38323	MCX1_YEAST	Mitochondrial clpX-like chaperone MCX1	9827555	Mcx1p, a ClpX homologue in mitochondria of Saccharomyces cerevisiae.

P77463	DDPC_ECOLI	Probable D,D-dipeptide transport system permease protein ddpC	11867724	Rapid topology mapping of Escherichia coli inner-membrane proteins by prediction and PhoA/GFP fusion analysis.

P49454	CENPF_HUMAN	Centromere protein F	7642639	The C-terminus of mitosin is essential for its nuclear localization, centromere/kinetochore targeting, and dimerization.

O94603	JHD1_SCHPO	Putative JmjC domain-containing histone demethylation protein 1	12773576	A novel jmjC domain protein modulates heterochromatization in fission yeast.

Q9UBN4	TRPC4_HUMAN	Short transient receptor potential channel 4	15757897	MxA, a member of the dynamin superfamily, interacts with the ankyrin- like repeat domain of TRPC.

P02406	RL28_YEAST	60S ribosomal protein L28	2104804	Characterization of nuclear localizing sequences derived from yeast ribosomal protein L29.

P49775	HNT2_YEAST	Bis(5'-adenosyl)-triphosphatase	9573184	Control of 5',5'-dinucleoside triphosphate catabolism by APH1, a Saccharomyces cerevisiae analog of human FHIT.

P15303	SEC23_YEAST	Protein transport protein SEC23	9325247	COPII subunit interactions in the assembly of the vesicle coat.

Q8VD75	HIP1_MOUSE	Huntingtin-interacting protein 1	12839988	Disruption of the endocytic protein HIP1 results in neurological deficits and decreased AMPA receptor trafficking.

O48962	EBP_ARATH	Probable 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	9862498	Isolation and characterization of an Arabidopsis thaliana C-8,7 sterol isomerase: functional and structural similarities to mammalian C-8,7 sterol isomerase/emopamil-binding protein.

Q9BXW6	OSBL1_HUMAN	Oxysterol-binding protein-related protein 1	11279184	Novel members of the human oxysterol-binding protein family bind phospholipids and regulate vesicle transport.

Q91ZK0	AP2D_MOUSE	Transcription factor AP-2-delta	11522791	Cloning and characterization of a novel mouse AP-2 transcription factor, AP-2delta, with unique DNA binding and transactivation properties.

Q923K9	A1CF_RAT	APOBEC1 complementation factor	11870221	The editosome for cytidine to uridine mRNA editing has a native complexity of 27S: identification of intracellular domains containing active and inactive editing factors.

P11908	PRPS2_HUMAN	Ribose-phosphate pyrophosphokinase 2	2538352	Molecular cloning and sequencing of human cDNA for phosphoribosyl pyrophosphate synthetase subunit II.

A2CEI6	PIWL2_DANRE	Piwi-like protein 2	18833190	Zili is required for germ cell differentiation and meiosis in zebrafish.

P40554	URM1_YEAST	Ubiquitin-related modifier 1	19151091	Mechanistic characterization of the sulfur-relay system for eukaryotic 2-thiouridine biogenesis at tRNA wobble positions.

O43916	CHST1_HUMAN	Carbohydrate sulfotransferase 1	10330415	Sulfotransferases of two specificities function in the reconstitution of high endothelial cell ligands for L-selectin.

P38175	RT21_YEAST	37S ribosomal protein MRP21, mitochondrial	9528754	Functional interactions between yeast mitochondrial ribosomes and mRNA 5' untranslated leaders.

Q2TB02	IKBD_MOUSE	NF-kappa-B inhibitor delta	11931770	Peptide-induced negative selection of thymocytes activates transcription of an NF-kappa B inhibitor.

P63004	LIS1_RAT	Platelet-activating factor acetylhydrolase IB subunit alpha	16144905	LIS1 RNA interference blocks neural stem cell division, morphogenesis, and motility at multiple stages.

Q8UVX0	PIWL1_DANRE	Piwi-like protein 1	14516689	Ziwi, the zebrafish homologue of the Drosophila piwi: co-localization with vasa at the embryonic genital ridge and gonad-specific expression in the adults.

Q9C002	NMES1_HUMAN	Normal mucosa of esophagus-specific gene 1 protein	12209954	A novel gene, NMES1, downregulated in human esophageal squamous cell carcinoma.

P25300	BUD5_YEAST	Bud site selection protein 5	11589573	Overexpression of Bud5p can suppress mutations in the Gsp1p guanine nucleotide exchange factor Prp20p in Saccharomyces cerevisiae.

P54644	KRAC_DICDI	RAC family serine/threonine-protein kinase homolog	18635356	PIP3-independent activation of TorC2 and PKB at the cell's leading edge mediates chemotaxis.

Q06338	BCP1_YEAST	Protein BCP1	12912920	Regulation of PI4,5P2 synthesis by nuclear-cytoplasmic shuttling of the Mss4 lipid kinase.

P43286	PIP21_ARATH	Aquaporin PIP2-1	7920711	Water channels in the plant plasma membrane cloned by immunoselection from a mammalian expression system.

Q9QXQ1	PDE7B_MOUSE	cAMP-specific 3',5'-cyclic phosphodiesterase 7B	10872825	Cloning and characterisation of the human and mouse PDE7B, a novel cAMP-specific nucleotide phosphodiesterase.

Q8VHQ2	SOCS7_MOUSE	Suppressor of cytokine signaling 7	16127460	Deletion of SOCS7 leads to enhanced insulin action and enlarged islets of Langerhans.

P16658	SEN2_YEAST	tRNA-splicing endonuclease subunit SEN2	2182322	Accumulation of pre-tRNA splicing '2/3' intermediates in a Saccharomyces cerevisiae mutant.

P28861	FENR_ECOLI	Ferredoxin--NADP reductase	8449868	Escherichia coli ferredoxin NADP+ reductase: activation of E. coli anaerobic ribonucleotide reduction, cloning of the gene (fpr), and overexpression of the protein.

O34876	FTSX_BACSU	Cell division protein ftsX	18573177	The FtsEX ABC transporter directs cellular differentiation in Bacillus subtilis.

Q9Y2T7	YBOX2_HUMAN	Y-box-binding protein 2	10100484	Contrin, the human homologue of a germ-cell Y-box-binding protein: cloning, expression, and chromosomal localization.

P30793	GCH1_HUMAN	GTP cyclohydrolase 1	16338639	The assays of activities and function of TH, AADC, and GCH1 and their potential use in ex vivo gene therapy of PD.

Q8NHV9	RHXF1_HUMAN	Rhox homeobox family member 1	12490318	Two novel human X-linked homeobox genes, hPEPP1 and hPEPP2, selectively expressed in the testis.

Q24255	BARH1_DROME	Homeobox protein B-H1	10068639	Bar homeobox genes are latitudinal prepattern genes in the developing Drosophila notum whose expression is regulated by the concerted functions of decapentaplegic and wingless.

P53854	CWC25_YEAST	Pre-mRNA-splicing factor CWC25	11884590	Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

Q2L6L1	CNPY1_DANRE	Protein canopy-1	16488878	Canopy1, a novel regulator of FGF signaling around the midbrain- hindbrain boundary in zebrafish.

Q9FN69	GL3_ARATH	Transcription factor GLABRA 3	15590742	The bHLH genes GL3 and EGL3 participate in an intercellular regulatory circuit that controls cell patterning in the Arabidopsis root epidermis.

P41815	BAP3_YEAST	Valine amino-acid permease	10654085	Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae.

Q9LU77	PIN2_ARATH	Auxin efflux carrier component 2	9843496	AtPIN2 defines a locus of Arabidopsis for root gravitropism control.

B5LUR0	FALX8_LITFA	Preprofallaxidin-8	18803332	The fallaxidin peptides from the skin secretion of the eastern dwarf tree frog Litoria fallax. Sequence determination by positive and negative ion electrospray mass spectrometry: antimicrobial activity and cDNA cloning of the fallaxidins.

P40563	AIM21_YEAST	Altered inheritance of mitochondria protein 21	14737190	Protein interaction networks by proteome peptide scanning.

O94513	EIF3E_SCHPO	Eukaryotic translation initiation factor 3 subunit E	11121040	Yin6, a fission yeast Int6 homolog, complexes with moe1 and plays a role in chromosome segregation.

P08729	K2C7_HUMAN	Keratin, type II cytoskeletal 7	11169732	Molecular interaction between human tumor marker protein p150, the largest subunit of eIF3, and intermediate filament protein K7.

O80345	CDKF1_ARATH	Cyclin-dependent kinase F-1	9560221	A distinct cyclin-dependent kinase-activating kinase of Arabidopsis thaliana.

Q9LW29	AFB2_ARATH	Protein AUXIN SIGNALING F-BOX 2	16627744	A plant miRNA contributes to antibacterial resistance by repressing auxin signaling.

Q9UTL6	JAC1_SCHPO	J-type co-chaperone jac1, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P53725	MPP6_YEAST	M-phase phosphoprotein 6 homolog	19046973	Comparative multiplexed mass spectrometric analyses of endogenously expressed yeast nuclear and cytoplasmic exosomes.

Q9ERC1	MYO16_RAT	Myosin-XVI	11588169	Myr 8, a novel unconventional myosin expressed during brain development associates with the protein phosphatase catalytic subunits 1alpha and 1gamma1.

Q9BVG8	KIFC3_HUMAN	Kinesin-like protein KIFC3	19041755	Anchorage of microtubule minus ends to adherens junctions regulates epithelial cell-cell contacts.

P63272	SPT4H_HUMAN	Transcription elongation factor SPT4	9857195	Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription in vitro.

Q5VYK3	ECM29_HUMAN	Proteasome-associated protein ECM29 homolog	15496406	Characterization of mammalian Ecm29, a 26 S proteasome-associated protein that localizes to the nucleus and membrane vesicles.

Q9H598	VIAAT_HUMAN	Vesicular inhibitory amino acid transporter	12115694	Cellular localization of the vesicular inhibitory amino acid transporter in the mouse and human retina.

Q9JLZ1	GLRX3_RAT	Glutaredoxin-3	10636891	Inhibition of the c-Jun N-terminal kinase/AP-1 and NF-kappaB pathways by PICOT, a novel protein kinase C-interacting protein with a thioredoxin homology domain.

Q9Z2Q4	METH_RAT	Methionine synthase	9972236	Cloning, sequencing, and heterologous expression of rat methionine synthase cDNA.

Q24478	CP190_DROME	Centrosome-associated zinc finger protein CP190	1372522	Purification of a multiprotein complex containing centrosomal proteins from the Drosophila embryo by chromatography with low- affinity polyclonal antibodies.

Q9V460	SPT5H_DROME	Transcription elongation factor SPT5	11040216	Spt5 and spt6 are associated with active transcription and have characteristics of general elongation factors in D. melanogaster.

P03971	MIS_HUMAN	Muellerian-inhibiting factor	3754790	Isolation of the bovine and human genes for Mullerian inhibiting substance and expression of the human gene in animal cells.

P36659	CBPA_ECOLI	Curved DNA-binding protein	10551881	Twelve species of the nucleoid-associated protein from Escherichia coli. Sequence recognition specificity and DNA binding affinity.

P35030	TRY3_HUMAN	Trypsin-3	2326201	Nucleotide sequence of the human pancreatic trypsinogen III cDNA.

P39717	GPB2_YEAST	Guanine nucleotide-binding protein subunit beta 2	16278446	Cyclic AMP-independent regulation of protein kinase A substrate phosphorylation by Kelch repeat proteins.

P25373	GLRX1_YEAST	Glutaredoxin-1	12684511	Role of yeast glutaredoxins as glutathione S-transferases.

P05387	RLA2_HUMAN	60S acidic ribosomal protein P2	3323886	Human acidic ribosomal phosphoproteins P0, P1, and P2: analysis of cDNA clones, in vitro synthesis, and assembly.

P83871	PHF5A_RAT	PHD finger-like domain-containing protein 5A	12810571	Ini, a small nuclear protein that enhances the response of the connexin43 gene to estrogen.

P51170	SCNNG_HUMAN	Amiloride-sensitive sodium channel subunit gamma	11244092	The Nedd4-like protein KIAA0439 is a potential regulator of the epithelial sodium channel.

Q60997	DMBT1_MOUSE	Deleted in malignant brain tumors 1 protein	12884308	CRP-ductin, the mouse homologue of gp-340/deleted in malignant brain tumors 1 (DMBT1), binds gram-positive and gram-negative bacteria and interacts with lung surfactant protein D.

Q8VZ17	SUVH6_ARATH	Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH6	15014946	Dimethylation of histone H3 lysine 9 is a critical mark for DNA methylation and gene silencing in Arabidopsis thaliana.

P31779	TTHY_RANCA	Transthyretin	8477670	Purification and characterization of a 3,5,3'-L-triiodothyronine- specific binding protein from bullfrog tadpole plasma: a homolog of mammalian transthyretin.

P00533	EGFR_HUMAN	Epidermal growth factor receptor	6325948	ATP-stimulated interaction between epidermal growth factor receptor and supercoiled DNA.

P25379	STDH_YEAST	Catabolic L-serine/threonine dehydratase	14562095	Global analysis of protein localization in budding yeast.

P22273	IL6RA_RAT	Interleukin-6 receptor subunit alpha	2174054	Molecular cloning, characterization and functional expression of the rat liver interleukin 6 receptor.

P96797	HDRD_METBF	CoB--CoM heterodisulfide reductase iron-sulfur subunit D	8174566	Purification of a two-subunit cytochrome-b-containing heterodisulfide reductase from methanol-grown Methanosarcina barkeri.

Q9ERC8	DSCAM_MOUSE	Down syndrome cell adhesion molecule homolog	18585357	DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1.

P10499	KCNA1_RAT	Potassium voltage-gated channel subfamily A member 1	16504945	The epilepsy-linked Lgi1 protein assembles into presynaptic Kv1 channels and inhibits inactivation by Kvbeta1.

P23803	ODD_DROME	Protein odd-skipped	9806933	Dynamic changes in the functions of Odd-skipped during early Drosophila embryogenesis.

Q9P7W4	POF10_SCHPO	F-box/WD repeat-containing protein pof10	11820777	Isolation and characterization of a novel F-box protein Pof10 in fission yeast.

Q01882	RAG2_ORYSJ	Seed allergenic protein RAG2	7678765	Gene structure and expression of rice seed allergenic proteins belonging to the alpha-amylase/trypsin inhibitor family.

O96690	PDF_DROME	Protein PDF	9615286	Isolation and chronobiological analysis of a neuropeptide pigment- dispersing factor gene in Drosophila melanogaster.

Q9H3N8	HRH4_HUMAN	Histamine H4 receptor	11118334	Molecular cloning and characterization of a new human histamine receptor, HH4R.

O15344	TRI18_HUMAN	Midline-1	10077590	The Opitz syndrome gene product, MID1, associates with microtubules.

Q9UTP3	FTA6_SCHPO	Kinetochore protein fta6	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9P7M3	SLX1_SCHPO	Structure-specific endonuclease subunit slx1	16467377	Rad22Rad52-dependent repair of ribosomal DNA repeats cleaved by Slx1- Slx4 endonuclease.

Q9JKX6	NUDT5_MOUSE	ADP-sugar pyrophosphatase	10722730	Cloning and characterization of a new member of the Nudix hydrolases from human and mouse.

P53944	MTQ1_YEAST	Mitochondrial N(5)-glutamine methyltransferase MTQ1	14562095	Global analysis of protein localization in budding yeast.

Q9JLP1	KHDR3_RAT	KH domain-containing, RNA-binding, signal transduction-associated protein 3	11118435	The STAR/GSG family protein rSLM-2 regulates the selection of alternative splice sites.

P07316	CRGB_HUMAN	Gamma-crystallin B	12507494	Homology models of human gamma-crystallins: structural study of the extensive charge network in gamma-crystallins.

Q8BGE7	TRIM6_MOUSE	Tripartite motif-containing protein 6	11331580	The tripartite motif family identifies cell compartments.

Q84MC2	LOG8_ARATH	Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG8	19837870	Functional analyses of LONELY GUY cytokinin-activating enzymes reveal the importance of the direct activation pathway in Arabidopsis.

Q149T7	PPM1J_MOUSE	Protein phosphatase 1J	12633878	A novel protein phosphatase 2C family member (PP2Czeta) is able to associate with ubiquitin conjugating enzyme 9.

P28061	PSB_THEAC	Proteasome subunit beta	8999862	Processive degradation of proteins and other catalytic properties of the proteasome from Thermoplasma acidophilum.

P84842	BR2EC_RANSA	Brevinin-2Ec	16394170	Skin secretions of Rana saharica frogs reveal antimicrobial peptides esculentins-1 and -1B and brevinins-1E and -2EC with novel insulin releasing activity.

O75376	NCOR1_HUMAN	Nuclear receptor corepressor 1	14525983	DACH1 inhibits transforming growth factor-beta signaling through binding Smad4.

O36025	MPD2_SCHPO	GYF domain-containing protein mpd2	15094387	The fission yeast ptr1+ gene involved in nuclear mRNA export encodes a putative ubiquitin ligase.

Q9C0Z8	YKTB_SCHPO	Uncharacterized protein PB1E7.11c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q03611	CNG_CAEEL	Cyclic nucleotide-gated cation channel	8893027	Mutations in a cyclic nucleotide-gated channel lead to abnormal thermosensation and chemosensation in C. elegans.

Q9NS84	CHST7_HUMAN	Carbohydrate sulfotransferase 7	10781596	Molecular cloning and expression of a novel chondroitin 6-O- sulfotransferase.

O54747	DPOD1_RAT	DNA polymerase delta catalytic subunit	9620226	Evidence for reduced copying fidelity of DNA polymerases alpha, delta, and epsilon from Novikoff hepatoma cells.

P37275	ZEB1_HUMAN	Zinc finger E-box-binding homeobox 1	1840704	Identification of a zinc finger protein that inhibits IL-2 gene expression.

P32913	VPS17_YEAST	Vacuolar protein sorting-associated protein 17	9700157	A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeast.

Q17551	RPM1_CAEEL	E3 ubiquitin-protein ligase rpm-1	10839354	rpm-1, a conserved neuronal gene that regulates targeting and synaptogenesis in C. elegans.

Q90Z08	U119B_DANRE	Protein unc-119 homolog B	15593328	unc-119 homolog required for normal development of the zebrafish nervous system.

Q9D3G9	RHOH_MOUSE	Rho-related GTP-binding protein RhoH	19124738	RhoH plays critical roles in Fc epsilon RI-dependent signal transduction in mast cells.

O88831	KKCC2_RAT	Calcium/calmodulin-dependent protein kinase kinase 2	9276695	Molecular cloning of Ca2+/calmodulin-dependent protein kinase kinase beta.

O95935	TBX18_HUMAN	T-box transcription factor TBX18	9888994	Identification, mapping and phylogenomic analysis of four new human members of the T-box gene family: EOMES, TBX6, TBX18, and TBX19.

Q96291	BAS1A_ARATH	2-Cys peroxiredoxin BAS1, chloroplastic	16884685	The C-type Arabidopsis thioredoxin reductase ANTR-C acts as an electron donor to 2-Cys peroxiredoxins in chloroplasts.

Q8MMF9	OB57D_DROME	General odorant-binding protein 57d	12213773	Genome-wide analysis of the odorant-binding protein gene family in Drosophila melanogaster.

P42771	CD2A1_HUMAN	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3	17658461	Identification and characterization of a novel protein ISOC2 that interacts with p16INK4a.

Q9BY79	MFRP_HUMAN	Membrane frizzled-related protein	11263980	Molecular cloning and characterization of MFRP, a novel gene encoding a membrane-type frizzled-related protein.

Q9SR37	BGL23_ARATH	Beta-glucosidase 23	18248598	PYK10, a beta-glucosidase located in the endoplasmatic reticulum, is crucial for the beneficial interaction between Arabidopsis thaliana and the endophytic fungus Piriformospora indica.

Q12469	SKM1_YEAST	Serine/threonine-protein kinase SKM1	9044278	Characterization of SKM1, a Saccharomyces cerevisiae gene encoding a novel Ste20/PAK-like protein kinase.

Q5QP82	DCA10_HUMAN	DDB1- and CUL4-associated factor 10	16949367	A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1.

O93464	CCKN_CARAU	Cholecystokinin	10640690	Postprandial, seasonal and sexual variations in cholecystokinin gene expression in goldfish brain.

Q5QGT7	RTP2_HUMAN	Receptor-transporting protein 2	15550249	RTP family members induce functional expression of mammalian odorant receptors.

Q22258	ATR_CAEEL	Serine/threonine-protein kinase ATR	11016841	Characterization of Ce-atl-1, an ATM-like gene from Caenorhabditis elegans.

Q96BK5	PINX1_HUMAN	PIN2/TERF1-interacting telomerase inhibitor 1	15381700	Characterization of interactions between PinX1 and human telomerase subunits hTERT and hTR.

O60504	VINEX_HUMAN	Vinexin	18662323	Characterization of a multidomain adaptor protein, p140Cap, as part of a pre-synaptic complex.

P33272	CP2BC_RAT	Cytochrome P450 2B12	1445240	Sequence of a novel cytochrome CYP2B cDNA coding for a protein which is expressed in a sebaceous gland, but not in the liver.

P38877	CTF8_YEAST	Chromosome transmission fidelity protein 8	11389843	Identification of RFC(Ctf18p, Ctf8p, Dcc1p): an alternative RFC complex required for sister chromatid cohesion in S. cerevisiae.

Q54YF2	AMPKA_DICDI	5'-AMP-activated serine/threonine-protein kinase catalytic subunit alpha	17332500	Diverse cytopathologies in mitochondrial disease are caused by AMP- activated protein kinase signaling.

O31728	SEPF_BACSU	Cell division protein sepF	16796675	A new FtsZ-interacting protein, YlmF, complements the activity of FtsA during progression of cell division in Bacillus subtilis.

O77203	PIAA_DICDI	Protein pianissimo A	18635356	PIP3-independent activation of TorC2 and PKB at the cell's leading edge mediates chemotaxis.

Q62083	PICK1_MOUSE	PRKCA-binding protein	10340301	The protein kinase C alpha binding protein PICK1 interacts with short but not long form alternative splice variants of AMPA receptor subunits.

Q9QXJ0	TTL_RAT	Tubulin--tyrosine ligase	9108330	Tubulin tyrosine ligase: protein and mRNA expression in developing rat skeletal muscle.

Q9M3H5	AHM1_ARATH	Probable cadmium/zinc-transporting ATPase HMA1, chloroplastic	12766230	Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.

P0A9P6	DEAD_ECOLI	Cold-shock DEAD box protein A	15554978	Physical and functional interactions among RNase E, polynucleotide phosphorylase and the cold-shock protein, CsdA: evidence for a 'cold shock degradosome'.

P09440	C1TM_YEAST	C-1-tetrahydrofolate synthase, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q10262	MU115_SCHPO	Meiotically up-regulated gene 115 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8WXF7	ATLA1_HUMAN	Atlastin-1	14506257	Cellular localization, oligomerization, and membrane association of the hereditary spastic paraplegia 3A (SPG3A) protein atlastin.

O75306	NDUS2_HUMAN	NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial	19463981	Mutations in NDUFAF3 (C3ORF60), encoding an NDUFAF4 (C6ORF66)- interacting complex I assembly protein, cause fatal neonatal mitochondrial disease.

P85253	CTX11_LACTA	M-zodatoxin-Lt8a	18215128	Cyto-insectotoxins, a novel class of cytolytic and insecticidal peptides from spider venom.

Q9NIV0	RHGA_DICDI	Rhesus-like glycoprotein A	16478785	Acidic clusters target transmembrane proteins to the contractile vacuole in Dictyostelium cells.

O60175	OPI10_SCHPO	Protein OPI10 homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P13668	STMN1_RAT	Stathmin	2745432	A single cDNA encodes two isoforms of stathmin, a developmentally regulated neuron-enriched phosphoprotein.

P10912	GHR_HUMAN	Growth hormone receptor	7565946	Mutations of the growth hormone receptor in children with idiopathic short stature.

P30047	GFRP_HUMAN	GTP cyclohydrolase 1 feedback regulatory protein	16696853	A yeast 2-hybrid analysis of human GTP cyclohydrolase I protein interactions.

O75751	S22A3_HUMAN	Solute carrier family 22 member 3	10966924	Structure, function, and regional distribution of the organic cation transporter OCT3 in the kidney.

P53261	PESC_YEAST	Pescadillo homolog	11911362	Saccharomyces cerevisiae nucleolar protein Nop7p is necessary for biogenesis of 60S ribosomal subunits.

P38129	TAF5_YEAST	Transcription initiation factor TFIID subunit 5	12138208	Molecular characterization of Saccharomyces cerevisiae TFIID.

P97541	HSPB6_RAT	Heat shock protein beta-6	8921906	cDNA cloning of a 20-kDa protein (p20) highly homologous to small heat shock proteins: developmental and physiological changes in rat hindlimb muscles.

P59259	H4_ARATH	Histone H4	17242155	VIM1, a methylcytosine-binding protein required for centromeric heterochromatinization.

P0C0S1	MSCS_ECOLI	Small-conductance mechanosensitive channel	12080120	Purification of the small mechanosensitive channel of Escherichia coli (MscS): the subunit structure, conduction, and gating characteristics in liposomes.

Q96CA5	BIRC7_HUMAN	Baculoviral IAP repeat-containing protein 7	11084335	ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas.

Q08622	FMP38_YEAST	Mitochondrial protein FMP38	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q9YGK8	IRX1A_XENLA	Iroquois-class homeodomain protein irx-1-A	18715948	A dual requirement for Iroquois genes during Xenopus kidney development.

P0AFD4	NUOH_ECOLI	NADH-quinone oxidoreductase subunit H	15919996	Global topology analysis of the Escherichia coli inner membrane proteome.

Q12380	ATG5_YEAST	Autophagy protein 5	10712513	Apg5p functions in the sequestration step in the cytoplasm-to-vacuole targeting and macroautophagy pathways.

O15173	PGRC2_HUMAN	Membrane-associated progesterone receptor component 2	9705155	Cloning and tissue expression of two putative steroid membrane receptors.

Q9P0Z9	SOX_HUMAN	Peroxisomal sarcosine oxidase	10642506	L-pipecolic acid oxidase, a human enzyme essential for the degradation of L-pipecolic acid, is most similar to the monomeric sarcosine oxidases.

P08861	CEL3B_HUMAN	Chymotrypsin-like elastase family member 3B	2826474	Identification of a novel class of elastase isozyme, human pancreatic elastase III, by cDNA and genomic gene cloning.

Q4JIM5	ABL2_MOUSE	Tyrosine-protein kinase ABL2	11752434	The Abl-related gene (Arg) nonreceptor tyrosine kinase uses two F- actin-binding domains to bundle F-actin.

P14306	CPYI_YEAST	Carboxypeptidase Y inhibitor	9521655	A high-affinity inhibitor of yeast carboxypeptidase Y is encoded by TFS1 and shows homology to a family of lipid binding proteins.

Q91ZF1	IRK15_RAT	ATP-sensitive inward rectifier potassium channel 15	11804844	Cloning, expression, and localization of a rat hepatocyte inwardly rectifying potassium channel.

Q93WK5	APRR7_ARATH	Two-component response regulator-like APRR7	14563930	Arabidopsis PSEUDO-RESPONSE REGULATOR 7 is a signaling intermediate in phytochrome-regulated seedling deetiolation and phasing of the circadian clock.

O59731	YHXB_SCHPO	Uncharacterized J domain-containing protein C3E7.11c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P84827	SKSP2_ASCTR	Skin secreted peptide 2	15922344	Bradykinin-related peptides and tryptophyllins in the skin secretions of the most primitive extant frog, Ascaphus truei.

P36051	MCD4_YEAST	GPI ethanolamine phosphate transferase 1	12807869	ATP uptake in the Golgi and extracellular release require Mcd4 protein and the vacuolar H+-ATPase.

Q9UKE5	TNIK_HUMAN	TRAF2 and NCK-interacting protein kinase	19816403	The kinase TNIK is an essential activator of Wnt target genes.

Q14160	SCRIB_HUMAN	Protein scribble homolog	16344308	The mammalian Scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherin.

Q9S3R8	OMP40_PORGI	Outer membrane protein 40	11532011	Identification of a novel heterodimeric outer membrane protein of Porphyromonas gingivalis by two-dimensional gel electrophoresis and peptide mass fingerprinting.

O75747	P3C2G_HUMAN	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma	9878262	cDNA cloning of a third human C2-domain-containing class II phosphoinositide 3-kinase, PI3K-C2gamma, and chromosomal assignment of this gene (PIK3C2G) to 12p12.

Q8IWW8	HOT_HUMAN	Hydroxyacid-oxoacid transhydrogenase, mitochondrial	16435184	Kinetic characterization of human hydroxyacid-oxoacid transhydrogenase: relevance to D-2-hydroxyglutaric and gamma- hydroxybutyric acidurias.

P60844	AQPZ_ECOLI	Aquaporin Z	10518952	Functional reconstitution and characterization of AqpZ, the E. coli water channel protein.

Q54KF7	SIBA_DICDI	Integrin beta-like protein A	16699495	An adhesion molecule in free-living Dictyostelium amoebae with integrin beta features.

O75581	LRP6_HUMAN	Low-density lipoprotein receptor-related protein 6	20059949	Cell cycle control of wnt receptor activation.

P38626	NCB5R_YEAST	NADH-cytochrome b5 reductase 1	16407407	Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins.

Q9WUH2	LHX9_MOUSE	LIM/homeobox protein Lhx9	10706291	The LIM homeobox gene Lhx9 is essential for mouse gonad formation.

P39001	UME6_YEAST	Transcriptional regulatory protein UME6	8618927	UME6 is a central component of a developmental regulatory switch controlling meiosis-specific gene expression.

Q13136	LIPA1_HUMAN	Liprin-alpha-1	7796809	The LAR transmembrane protein tyrosine phosphatase and a coiled-coil LAR-interacting protein co-localize at focal adhesions.

Q9USQ8	YN1B_SCHPO	Uncharacterized protein C577.11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P30553	GASR_RAT	Gastrin/cholecystokinin type B receptor	1528881	Brain and gastrointestinal cholecystokinin receptor family: structure and functional expression.

Q8CDG1	PIWL2_MOUSE	Piwi-like protein 2	18922463	A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice.

P18297	SPRE_RAT	Sepiapterin reductase	2201030	Isolation and expression of rat liver sepiapterin reductase cDNA.

Q7TNK1	RFX4_MOUSE	Transcription factor RFX4	16893423	Identification of potential target genes for RFX4_v3, a transcription factor critical for brain development.

Q6NZY4	ZCHC8_HUMAN	Zinc finger CCHC domain-containing protein 8	17525332	ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

O14157	MYO3_SCHPO	Myosin type-2 heavy chain 2	9398685	Identification of a second myosin-II in Schizosaccharomyces pombe: Myp2p is conditionally required for cytokinesis.

Q9VD44	GLD2A_DROME	Poly(A) RNA polymerase gld-2 homolog A	18780789	GLD2 poly(A) polymerase is required for long-term memory.

O54885	TYOBP_MOUSE	TYRO protein tyrosine kinase-binding protein	12893283	Identification and characterization of a new pair of immunoglobulin- like receptors LMIR1 and 2 derived from murine bone marrow-derived mast cells.

Q5EAK6	ATM_DROME	Serine/threonine-protein kinase ATM	16203987	Drosophila ATM and ATR checkpoint kinases control partially redundant pathways for telomere maintenance.

P97857	ATS1_MOUSE	A disintegrin and metalloproteinase with thrombospondin motifs 1	8995297	Molecular cloning of a gene encoding a new type of metalloproteinase- disintegrin family protein with thrombospondin motifs as an inflammation associated gene.

Q14493	SLBP_HUMAN	Histone RNA hairpin-binding protein	19155325	Knockdown of SLBP results in nuclear retention of histone mRNA.

Q96EP1	CHFR_HUMAN	E3 ubiquitin-protein ligase CHFR	18172500	Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins.

Q75JK0	ZAKA_DICDI	Dual specificity protein kinase zakA	17085634	Proteomic and microarray analyses of the Dictyostelium Zak1-GSK-3 signaling pathway reveal a role in early development.

P22352	GPX3_HUMAN	Glutathione peroxidase 3	1897960	Characterization and partial amino acid sequence of human plasma glutathione peroxidase.

Q9NQW6	ANLN_HUMAN	Actin-binding protein anillin	10931866	Functional analysis of a human homolog of the Drosophila actin binding protein anillin suggests a role in cytokinesis.

Q9UN37	VPS4A_HUMAN	Vacuolar protein sorting-associated protein 4A	18606141	Two distinct modes of ESCRT-III recognition are required for VPS4 functions in lysosomal protein targeting and HIV-1 budding.

O08962	KCNH2_RAT	Potassium voltage-gated channel subfamily H member 2	11212207	Erg1, erg2 and erg3 K channel subunits are able to form heteromultimers.

Q07283	TRHY_HUMAN	Trichohyalin	7685034	The structure of human trichohyalin. Potential multiple roles as a functional EF-hand-like calcium-binding protein, a cornified cell envelope precursor, and an intermediate filament-associated (cross- linking) protein.

O94761	RECQ4_HUMAN	ATP-dependent DNA helicase Q4	9878247	Cloning of two new human helicase genes of the RecQ family: biological significance of multiple species in higher eukaryotes.

P32344	COX24_YEAST	Mitochondrial mRNA-processing protein COX24	14562095	Global analysis of protein localization in budding yeast.

P06881	CALCA_HUMAN	Calcitonin gene-related peptide 1	2408883	Expression of the human calcitonin/CGRP gene in lung and thyroid carcinoma.

P16303	CES3_RAT	Carboxylesterase 3	2386485	Nucleotide sequence of cDNA coding for rat liver pI 6.1 esterase (ES- 10), a carboxylesterase located in the lumen of the endoplasmic reticulum.

Q13888	TF2H2_HUMAN	General transcription factor IIH subunit 2	8194529	p44 and p34 subunits of the BTF2/TFIIH transcription factor have homologies with SSL1, a yeast protein involved in DNA repair.

Q9V535	RBM8A_DROME	RNA-binding protein 8A	12730685	A novel mode of RBD-protein recognition in the Y14-Mago complex.

Q9QZH8	AAAD_RAT	Arylacetamide deacetylase	11481320	Characterization of the rodent genes for arylacetamide deacetylase, a putative microsomal lipase, and evidence for transcriptional regulation.

P12868	PEP5_YEAST	Vacuolar membrane protein PEP5	10978279	Pep3p/Pep5p complex: a putative docking factor at multiple steps of vesicular transport to the vacuole of Saccharomyces cerevisiae.

Q8MXY0	AMT3_DICDI	Ammonium transporter 3	16188250	Ammonium transporter C of Dictyostelium discoideum is required for correct prestalk gene expression and for regulating the choice between slug migration and culmination.

P07991	OAT_YEAST	Ornithine aminotransferase	3036506	Molecular characterization of transposable-element-associated mutations that lead to constitutive L-ornithine aminotransferase expression in Saccharomyces cerevisiae.

Q11205	SIA4B_RAT	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2	8144500	Cloning and expression of cDNA for a new type of Gal beta 1,3GalNAc alpha 2,3-sialyltransferase.

Q96D31	CRCM1_HUMAN	Calcium release-activated calcium channel protein 1	20418871	A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cells.

P43621	COPD_YEAST	Coatomer subunit delta	8617224	Delta- and zeta-COP, two coatomer subunits homologous to clathrin- associated proteins, are involved in ER retrieval.

Q3ZAQ7	VMA21_HUMAN	Vacuolar ATPase assembly integral membrane protein VMA21	19379691	VMA21 deficiency causes an autophagic myopathy by compromising V- ATPase activity and lysosomal acidification.

C6KFA3	GP126_DANRE	G-protein coupled receptor 126	19745155	A G protein-coupled receptor is essential for Schwann cells to initiate myelination.

Q6P2E9	EDC4_HUMAN	Enhancer of mRNA-decapping protein 4	9067524	Cytoplasmic detection of a novel protein containing a nuclear localization sequence by human autoantibodies.

Q9VXE5	PAKM_DROME	Serine/threonine-protein kinase PAK mbt	12490550	Mbt, a Drosophila PAK protein, combines with Cdc42 to regulate photoreceptor cell morphogenesis.

P38169	KMO_YEAST	Kynurenine 3-monooxygenase	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P87242	YC0H_SCHPO	HD domain-containing protein C4G3.17	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q09804	URB2_SCHPO	Probable nucleolar pre-ribosomal-associated protein 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O43556	SGCE_HUMAN	Epsilon-sarcoglycan	9475163	Human epsilon-sarcoglycan is highly related to alpha-sarcoglycan (adhalin), the limb girdle muscular dystrophy 2D gene.

Q9UL03	INT6_HUMAN	Integrator complex subunit 6	16239144	Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.

P04076	ARLY_YEAST	Argininosuccinate lyase	6386606	The nucleotide sequence of the yeast ARG4 gene.

O75923	DYSF_HUMAN	Dysferlin	10496277	Dysferlin is a surface membrane-associated protein that is absent in Miyoshi myopathy.

P21372	PRP5_YEAST	Pre-mRNA-processing ATP-dependent RNA helicase PRP5	8969184	The Saccharomyces cerevisiae Prp5 protein has RNA-dependent ATPase activity with specificity for U2 small nuclear RNA.

Q9M4A1	SPO12_ARATH	Meiotic recombination protein SPO11-2	17965269	The catalytically active tyrosine residues of both SPO11-1 and SPO11- 2 are required for meiotic double-strand break induction in Arabidopsis.

Q9FN02	PPP7_ARATH	Serine/threonine-protein phosphatase 7	9862444	Expression and characterization of PP7, a novel plant protein Ser/Thr phosphatase distantly related to RdgC/PPEF and PP5.

Q86UT5	NHRF4_HUMAN	Na(+)/H(+) exchange regulatory cofactor NHE-RF4	19088451	Elevated intracellular calcium stimulates NHE3 activity by an IKEPP (NHERF4) dependent mechanism.

P39748	FEN1_HUMAN	Flap endonuclease 1	9305916	The DNA repair endonuclease XPG binds to proliferating cell nuclear antigen (PCNA) and shares sequence elements with the PCNA-binding regions of FEN-1 and cyclin-dependent kinase inhibitor p21.

P22011	PPIA_CANAL	Peptidyl-prolyl cis-trans isomerase	2269432	A Candida albicans homolog of a human cyclophilin gene encodes a peptidyl-prolyl cis-trans isomerase.

Q61103	REQU_MOUSE	Zinc finger protein ubi-d4	9680388	Expression and chromosomal localization of the Requiem gene.

Q9R210	TFEB_MOUSE	Transcription factor EB	9806910	The bHLH-Zip transcription factor Tfeb is essential for placental vascularization.

P63005	LIS1_MOUSE	Platelet-activating factor acetylhydrolase IB subunit alpha	15939891	Cytoplasmic LEK1 is a regulator of microtubule function through its interaction with the LIS1 pathway.

O14733	MP2K7_HUMAN	Dual specificity mitogen-activated protein kinase kinase 7	9535930	Human mitogen-activated protein kinase kinase 7 (MKK7) is a highly conserved c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) activated by environmental stresses and physiological stimuli.

Q9DGP9	DDX25_XENLA	ATP-dependent RNA helicase DDX25	10906480	DEADSouth is a germ plasm specific DEAD-box RNA helicase in Xenopus related to eIF4A.

O14156	PP2C4_SCHPO	Protein phosphatase 2C homolog 4	10436019	Vacuole fusion regulated by protein phosphatase 2C in fission yeast.

O65359	SYP41_ARATH	Syntaxin-41	10888666	AtVPS45 complex formation at the trans-Golgi network.

Q63811	CANB2_MOUSE	Calcineurin subunit B type 2	1325794	Structure and expression of two isoforms of the murine calmodulin- dependent protein phosphatase regulatory subunit (calcineurin B).

Q9SAK4	SSDH_ARATH	Succinate-semialdehyde dehydrogenase, mitochondrial	10517851	Plant succinic semialdehyde dehydrogenase. Cloning, purification, localization in mitochondria, and regulation by adenine nucleotides.

P41542	USO1_RAT	General vesicular transport factor p115	7831324	Transcytosis-associated protein (TAP)/p115 is a general fusion factor required for binding of vesicles to acceptor membranes.

P25651	CSM1_YEAST	Monopolin complex subunit CSM1	12689592	Kinetochore recruitment of two nucleolar proteins is required for homolog segregation in meiosis I.

Q8INK6	PGPLB_DROME	Peptidoglycan-recognition protein LB	11106397	A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster.

P32939	YPT7_YEAST	GTP-binding protein YPT7	1473149	Endocytosis in yeast: evidence for the involvement of a small GTP- binding protein (Ypt7p).

P46063	RECQ1_HUMAN	ATP-dependent DNA helicase Q1	7961977	Cloning and characterization of RECQL, a potential human homologue of the Escherichia coli DNA helicase RecQ.

Q8LPG9	IQD14_ARATH	Protein IQ-DOMAIN 14	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P52076	QSEB_ECOLI	Transcriptional regulatory protein qseB	11929534	Quorum sensing Escherichia coli regulators B and C (QseBC): a novel two-component regulatory system involved in the regulation of flagella and motility by quorum sensing in E. coli.

Q13315	ATM_HUMAN	Serine-protein kinase ATM	10550055	Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks.

Q9VT65	CANB_DROME	Calpain-B	14614768	Autolytic activation and localization in Schneider cells (S2) of calpain B from Drosophila.

P22749	GNLY_HUMAN	Granulysin	2212946	A cDNA clone expressed in natural killer and T cells that likely encodes a secreted protein.

Q94901	LARK_DROME	RNA-binding protein lark	9120432	Regulation of a specific circadian clock output pathway by lark, a putative RNA-binding protein with repressor activity.

Q9LMK5	STN1_ARATH	CST complex subunit STN1	19854131	Conserved telomere maintenance component 1 interacts with STN1 and maintains chromosome ends in higher eukaryotes.

Q9SKK0	EBF1_ARATH	EIN3-binding F-box protein 1	12169662	The F-box subunit of the SCF E3 complex is encoded by a diverse superfamily of genes in Arabidopsis.

Q12509	ARP6_YEAST	Actin-like protein ARP6	14645854	ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex.

O08561	PI4KB_RAT	Phosphatidylinositol 4-kinase beta	8973579	Cloning and characterization of a 92 kDa soluble phosphatidylinositol 4-kinase.

P14060	3BHS1_HUMAN	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1	1401999	Characterization, expression, and immunohistochemical localization of 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase in human skin.

Q99967	CITE2_HUMAN	Cbp/p300-interacting transactivator 2	9887100	Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1.

Q15843	NEDD8_HUMAN	NEDD8	15567417	Structure of a complex between Nedd8 and the Ulp/Senp protease family member Den1.

Q06408	ARO10_YEAST	Transaminated amino acid decarboxylase	12499363	The catabolism of amino acids to long chain and complex alcohols in Saccharomyces cerevisiae.

Q9Y566	SHAN1_HUMAN	SH3 and multiple ankyrin repeat domains protein 1	10551867	Somatostatin receptor interacting protein defines a novel family of multidomain proteins present in human and rodent brain.

P42526	HATB_DICDI	Hisactophilin-2	7822284	The pH-sensitive actin-binding protein hisactophilin of Dictyostelium exists in two isoforms which both are myristoylated and distributed between plasma membrane and cytoplasm.

P33991	MCM4_HUMAN	DNA replication licensing factor MCM4	8265339	The P1 family: a new class of nuclear mammalian proteins related to the yeast Mcm replication proteins.

Q14686	NCOA6_HUMAN	Nuclear receptor coactivator 6	11443112	Identification and characterization of RRM-containing coactivator activator (CoAA) as TRBP-interacting protein, and its splice variant as a coactivator modulator (CoAM).

Q9VEX9	SAP18_DROME	Histone deacetylase complex subunit SAP18	11256608	The GAGA factor of Drosophila interacts with SAP18, a Sin3-associated polypeptide.

Q9FFY9	TRP4_ARATH	Telomere repeat-binding protein 4	11513850	Sequence-specific binding property of Arabidopsis thaliana telomeric DNA binding protein 1 (AtTBP1).

O33246	PUP_MYCTU	Prokaryotic ubiquitin-like protein Pup	18832610	Ubiquitin-like protein involved in the proteasome pathway of Mycobacterium tuberculosis.

Q6NPR7	PMTO_ARATH	Probable methyltransferase PMT24	16618929	Mapping the Arabidopsis organelle proteome.

Q61466	SMRD1_MOUSE	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1	17640523	An essential switch in subunit composition of a chromatin remodeling complex during neural development.

Q9Z0E3	AIRE_MOUSE	Autoimmune regulator	11156688	Subcellular location and expression pattern of autoimmune regulator (Aire), the mouse orthologue for human gene defective in autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED).

Q00896	A1AT3_MOUSE	Alpha-1-antitrypsin 1-3	11961105	Functional diversification during evolution of the murine alpha(1)- proteinase inhibitor family: role of the hypervariable reactive center loop.

P12961	7B2_MOUSE	Neuroendocrine protein 7B2	8016065	The neuroendocrine polypeptide 7B2 is an endogenous inhibitor of prohormone convertase PC2.

P07947	YES_HUMAN	Proto-oncogene tyrosine-protein kinase Yes	2436037	Characterization of cDNA clones for the human c-yes gene.

Q8GZR2	CYF_EUGGR	Apocytochrome f, chloroplastic	12837550	Cytochrome f and subunit IV, two essential components of the photosynthetic bf complex typically encoded in the chloroplast genome, are nucleus-encoded in Euglena gracilis.

Q9NBD7	CLASP_DROME	CLIP-associating protein	10747094	Orbit, a novel microtubule-associated protein essential for mitosis in Drosophila melanogaster.

Q9USY3	NAA35_SCHPO	N-alpha-acetyltransferase, 35 NatC auxiliary subunit	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8IMN6	GR98C_DROME	Putative gustatory receptor 98c	10710312	Candidate taste receptors in Drosophila.

Q93088	BHMT1_HUMAN	Betaine--homocysteine S-methyltransferase 1	8798461	Purification, kinetic properties, and cDNA cloning of mammalian betaine-homocysteine methyltransferase.

P33991	MCM4_HUMAN	DNA replication licensing factor MCM4	9465298	The promoters for human DNA-PKcs (PRKDC) and MCM4: divergently transcribed genes located at chromosome 8 band q11.

Q9AT00	AB13I_ARATH	Protein TRIGALACTOSYLDIACYLGLYCEROL 3, chloroplastic	17938172	A small ATPase protein of Arabidopsis, TGD3, involved in chloroplast lipid import.

P53854	CWC25_YEAST	Pre-mRNA-splicing factor CWC25	14690591	Assigning function to yeast proteins by integration of technologies.

Q8N302	AGGF1_HUMAN	Angiogenic factor with G patch and FHA domains 1	14961121	Identification of an angiogenic factor that when mutated causes susceptibility to Klippel-Trenaunay syndrome.

Q01638	ILRL1_HUMAN	Interleukin-1 receptor-like 1	10527832	Presence and expression of a novel variant form of ST2 gene product in human leukemic cell line UT-7/GM.

Q08AM6	VAC14_HUMAN	Protein VAC14 homolog	8611628	Isolation of a cDNA clone, TRX encoding a human T-cell lymphotrophic virus type-I Tax1 binding protein.

Q9JHJ3	NCUG1_MOUSE	Lysosomal protein NCU-G1	19489740	NCU-G1 is a highly glycosylated integral membrane protein of the lysosome.

P53604	MSO1_YEAST	Protein MSO1	9207091	Mso1p: a yeast protein that functions in secretion and interacts physically and genetically with Sec1p.

P26378	ELAV4_HUMAN	ELAV-like protein 4	10710437	RNA-binding analyses of HuC and HuD with the VEGF and c-myc 3'- untranslated regions using a novel ELISA-based assay.

P07665	SRYB_DROME	Serendipity locus protein beta	1732741	Zinc fingers and other domains cooperate in binding of Drosophila sry beta and delta proteins at specific chromosomal sites.

Q60997	DMBT1_MOUSE	Deleted in malignant brain tumors 1 protein	15452149	Conversion of ES cells to columnar epithelia by hensin and to squamous epithelia by laminin.

Q9UN37	VPS4A_HUMAN	Vacuolar protein sorting-associated protein 4A	16174732	Structure and ESCRT-III protein interactions of the MIT domain of human VPS4A.

Q9T045	CBL11_ARATH	COBRA-like protein 11	12376623	The COBRA family of putative GPI-anchored proteins in Arabidopsis. A new fellowship in expansion.

Q6EVK6	BRM_ARATH	ATP-dependent helicase BRM	15371304	The Arabidopsis thaliana SNF2 homolog AtBRM controls shoot development and flowering.

P62615	ISPE_ECOLI	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase	10655484	Biosynthesis of terpenoids: YchB protein of Escherichia coli phosphorylates the 2-hydroxy group of 4-diphosphocytidyl-2C-methyl-D- erythritol.

P35555	FBN1_HUMAN	Fibrillin-1	8188302	A novel mutation of the fibrillin gene causing ectopia lentis.

Q9UTQ8	YL35_SCHPO	UPF0558 protein C1071.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q03019	TWINE_DROME	Cdc25-like protein phosphatase twine	1606618	Twine, a cdc25 homolog that functions in the male and female germline of Drosophila.

P87315	HIR3_SCHPO	Histone transcription regulator 3 homolog	16428807	Hip3 interacts with the HIRA proteins Hip1 and Slm9 and is required for transcriptional silencing and accurate chromosome segregation.

P25208	NFYB_HUMAN	Nuclear transcription factor Y subunit beta	12401788	The NF-YB/NF-YC structure gives insight into DNA binding and transcription regulation by CCAAT factor NF-Y.

Q9QZS2	RNF4_MOUSE	E3 ubiquitin ligase RNF4	10849425	Interaction between the transcription factor SPBP and the positive cofactor RNF4. An interplay between protein binding zinc fingers.

Q9CA67	CHLP_ARATH	Geranylgeranyl diphosphate reductase, chloroplastic	15028209	The Arabidopsis thaliana chloroplast proteome reveals pathway abundance and novel protein functions.

Q80UW2	FBX2_MOUSE	F-box only protein 2	12140560	E3 ubiquitin ligase that recognizes sugar chains.

Q05874	NNT1_YEAST	Putative nicotinamide N-methyltransferase	14562095	Global analysis of protein localization in budding yeast.

Q03180	PIR3_YEAST	Cell wall mannoprotein PIR3	9192695	Stress proteins on the yeast cell surface determine resistance to osmotin, a plant antifungal protein.

O22921	WRK25_ARATH	Probable WRKY transcription factor 25	15990873	The MAP kinase substrate MKS1 is a regulator of plant defense responses.

Q7YSW8	PP2BA_DICDI	Calcineurin subunit A	11352578	Unconventional mRNA processing in the expression of two calcineurin B isoforms in Dictyostelium.

P92199	ROCK_CAEEL	Rho-associated protein kinase let-502	12006612	Rho-binding kinase (LET-502) and myosin phosphatase (MEL-11) regulate cytokinesis in the early Caenorhabditis elegans embryo.

P58753	TIRAP_HUMAN	Toll/interleukin-1 receptor domain-containing adapter protein	11544529	Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction.

O94762	RECQ5_HUMAN	ATP-dependent DNA helicase Q5	9878247	Cloning of two new human helicase genes of the RecQ family: biological significance of multiple species in higher eukaryotes.

P09330	PRPS2_RAT	Ribose-phosphate pyrophosphokinase 2	2822704	Nucleotide and deduced amino acid sequences of two distinct cDNAs for rat phosphoribosylpyrophosphate synthetase.

O59711	LYS9_SCHPO	Saccharopine dehydrogenase [NADP+, L-glutamate-forming]	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P23352	KALM_HUMAN	Anosmin-1	1913827	The candidate gene for the X-linked Kallmann syndrome encodes a protein related to adhesion molecules.

P49956	CTF18_YEAST	Chromosome transmission fidelity protein 18	11287619	Saccharomyces cerevisiae CTF18 and CTF4 are required for sister chromatid cohesion.

Q99N90	RM36_MOUSE	39S ribosomal protein L36, mitochondrial	11279069	Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria.

Q58A65	JIP4_MOUSE	C-Jun-amino-terminal kinase-interacting protein 4	15767678	Role of the JIP4 scaffold protein in the regulation of mitogen- activated protein kinase signaling pathways.

Q54BC8	PSB5_DICDI	Proteasome subunit beta type-5	8130037	Proteasomes from Dictyostelium discoideum: characterization of structure and function.

P36165	TGL4_YEAST	Lipase 4	16135509	Tgl4p and Tgl5p, two triacylglycerol lipases of the yeast Saccharomyces cerevisiae are localized to lipid particles.

P24100	CDKA1_ARATH	Cyclin-dependent kinase A-1	16415207	The A-type cyclin CYCA2;3 is a key regulator of ploidy levels in Arabidopsis endoreduplication.

P60866	RS20_HUMAN	40S ribosomal protein S20	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

P29681	IMPE2_DROME	20-hydroxyecdysone protein	2115480	The Drosophila IMP-E2 gene encodes an apically secreted protein expressed during imaginal disc morphogenesis.

P47862	AQP3_RAT	Aquaporin-3	7526388	Cloning and expression of AQP3, a water channel from the medullary collecting duct of rat kidney.

P52553	PFD6_YEAST	Prefoldin subunit 6	9463374	A novel protein complex promoting formation of functional alpha- and gamma-tubulin.

Q02936	HH_DROME	Protein hedgehog	15691765	The Drosophila ortholog of the human wnt inhibitor factor shifted controls the diffusion of lipid-modified hedgehog.

Q27934	PHYL_DROME	Protein phyllopod	7888014	Phyllopod functions in the fate determination of a subset of photoreceptors in Drosophila.

Q07998	BRACA_DANRE	Brachyury protein homolog A	14660439	No tail co-operates with non-canonical Wnt signaling to regulate posterior body morphogenesis in zebrafish.

Q68EH9	CRBN_DANRE	Protein cereblon	20223979	Identification of a primary target of thalidomide teratogenicity.

Q9ZWI7	RER1C_ARATH	Protein RER1C	10737146	The Arabidopsis thaliana RER1 gene family: its potential role in the endoplasmic reticulum localization of membrane proteins.

P25613	ADY2_YEAST	Accumulation of dyads protein 2	12429834	Ammonia pulses and metabolic oscillations guide yeast colony development.

Q9UBP9	GULP1_HUMAN	PTB domain-containing engulfment adapter protein 1	10574763	The human homologue of Caenorhabditis elegans CED-6 specifically promotes phagocytosis of apoptotic cells.

Q9NYL9	TMOD3_HUMAN	Tropomodulin-3	10662549	Sequencing, expression analysis, and mapping of three unique human tropomodulin genes and their mouse orthologs.

Q7Z020	TRPA1_DROME	Transient receptor potential cation channel subfamily A member 1	15681611	The Drosophila ortholog of vertebrate TRPA1 regulates thermotaxis.

Q9BEE3	DB126_MACFA	Beta-defensin 126	10491631	The novel epididymal secretory protein ESP13.2 in Macaca fascicularis.

Q9NYB0	TE2IP_HUMAN	Telomeric repeat-binding factor 2-interacting protein 1	16166375	Shelterin: the protein complex that shapes and safeguards human telomeres.

Q8IU60	DCP2_HUMAN	mRNA-decapping enzyme 2	12417715	Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay.

O81635	ATK4_ARATH	Kinesin-4	10196470	Characterization of katD, a kinesin-like protein gene specifically expressed in floral tissues of Arabidopsis thaliana.

Q5IZC8	TC754_ARATH	Protein TOC75-4, chloroplastic	15908591	A molecular-genetic study of the Arabidopsis toc75 gene family.

P15891	ABP1_YEAST	Actin-binding protein	14737190	Protein interaction networks by proteome peptide scanning.

P40260	MEP1_YEAST	Ammonium transporter MEP1	9234685	A family of ammonium transporters in Saccharomyces cerevisiae.

Q9UHV7	MED13_HUMAN	Mediator of RNA polymerase II transcription subunit 13	10235267	Composite co-activator ARC mediates chromatin-directed transcriptional activation.

Q6UWZ7	F175A_HUMAN	BRCA1-A complex subunit Abraxas	17643121	CCDC98 targets BRCA1 to DNA damage sites.

Q13862	PBPL2_HUMAN	Putative platelet basic protein-like 2	7887923	DNA binding proteins that amplify surfactant protein B gene expression: isolation and characterization.

Q8WXG1	RSAD2_HUMAN	Radical S-adenosyl methionine domain-containing protein 2	9391139	Use of differential display analysis to assess the effect of human cytomegalovirus infection on the accumulation of cellular RNAs: induction of interferon-responsive RNAs.

O16868	FUZZY_DROME	Protein fuzzy	9374400	Drosophila tissue polarity requires the cell-autonomous activity of the fuzzy gene, which encodes a novel transmembrane protein.

Q99615	DNJC7_HUMAN	DnaJ homolog subfamily C member 7	8836031	Identification and characterization of two novel tetratricopeptide repeat-containing genes.

Q9VXH6	CANC_DROME	Calpain-C	12646209	Molecular cloning and RNA expression of a novel Drosophila calpain, Calpain C.

P35499	SCN4A_HUMAN	Sodium channel protein type 4 subunit alpha	10218481	Functional consequences of a domain 1/S6 segment sodium channel mutation associated with painful congenital myotonia.

O32504	PPRA_DEIRA	DNA repair protein pprA	15454524	Analysis of Deinococcus radiodurans's transcriptional response to ionizing radiation and desiccation reveals novel proteins that contribute to extreme radioresistance.

P52486	UBCD4_DROME	Ubiquitin-conjugating enzyme E2-22 kDa	11862484	UbcD4, a ubiquitin-conjugating enzyme in Drosophila melanogaster expressed in pole cells.

Q99M73	KRT84_MOUSE	Keratin, type II cuticular Hb4	1385239	Structural features and sites of expression of a new murine 65 kD and 48 kD hair-related keratin pair, associated with a special type of parakeratotic epithelial differentiation.

P52701	MSH6_HUMAN	DNA mismatch repair protein Msh6	8942985	hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6.

Q05066	SRY_HUMAN	Sex-determining region Y protein	8265659	The SRY high-mobility-group box recognizes DNA by partial intercalation in the minor groove: a topological mechanism of sequence specificity.

Q9H0A0	NAT10_HUMAN	N-acetyltransferase 10	11214970	Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

O43067	YGA3_SCHPO	Uncharacterized protein C6B1.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9P3E8	YLZ2_SCHPO	Uncharacterized transporter C750.02c/PB2B2.16c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O55176	PJA1_MOUSE	E3 ubiquitin-protein ligase Praja-1	9393880	Praja1, a novel gene encoding a RING-H2 motif in mouse development.

Q7M290	PMA_AVESA	Plasma membrane ATPase	16665938	Isolation and sequence of tryptic peptides from the proton-pumping ATPase of the oat plasma membrane.

Q99JB4	KRBBB_MOUSE	Killer cell lectin-like receptor subfamily B member 1B allele B	12858173	Genetically linked C-type lectin-related ligands for the NKRP1 family of natural killer cell receptors.

P41587	VIPR2_HUMAN	Vasoactive intestinal polypeptide receptor 2	7811244	Molecular cloning and functional characterization of a human VIP receptor from SUP-T1 lymphoblasts.

P53780	METC_ARATH	Cystathionine beta-lyase, chloroplastic	8541513	Cloning of an Arabidopsis thaliana cDNA encoding cystathionine beta- lyase by functional complementation in Escherichia coli.

Q96NR8	RDH12_HUMAN	Retinol dehydrogenase 12	12226107	Dual-substrate specificity short chain retinol dehydrogenases from the vertebrate retina.

Q9NWZ8	GEMI8_HUMAN	Gem-associated protein 8	16434402	Gemin8 is a novel component of the survival motor neuron complex and functions in small nuclear ribonucleoprotein assembly.

P27732	CAC1D_RAT	Voltage-dependent L-type calcium channel subunit alpha-1D	7479909	Multiple calcium channel transcripts in rat osteosarcoma cells: selective activation of alpha 1D isoform by parathyroid hormone.

P22680	CP7A1_HUMAN	Cholesterol 7-alpha-monooxygenase	19965590	Glucose stimulates cholesterol 7alpha-hydroxylase gene transcription in human hepatocytes.

Q9EPS3	GLCE_MOUSE	D-glucuronyl C5-epimerase	11274177	Characterization of the D-glucuronyl C5-epimerase involved in the biosynthesis of heparin and heparan sulfate.

Q9Z137	B3GA2_RAT	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2	10358066	Cloning and expression of a novel galactoside beta1,3- glucuronyltransferase involved in the biosynthesis of HNK-1 epitope.

Q1PFR7	LEC2_ARATH	B3 domain-containing transcription factor LEC2	11573014	LEAFY COTYLEDON2 encodes a B3 domain transcription factor that induces embryo development.

Q14894	CRYM_HUMAN	Mu-crystallin homolog	9328354	Purification, molecular cloning, and functional expression of the human nicodinamide-adenine dinucleotide phosphate-regulated thyroid hormone-binding protein.

Q91689	ZIC2A_XENLA	Zinc finger protein ZIC 2-A	16207750	Maternal Xenopus Zic2 negatively regulates Nodal-related gene expression during anteroposterior patterning.

Q09591	MIX1_CAEEL	Mitotic chromosome and X-chromosome-associated protein mix-1	11914278	C. elegans condensin promotes mitotic chromosome architecture, centromere organization, and sister chromatid segregation during mitosis and meiosis.

Q05860	FMN1_MOUSE	Formin-1	8516300	Formins: phosphoprotein isoforms encoded by the mouse limb deformity locus.

Q8BG60	TXNIP_MOUSE	Thioredoxin-interacting protein	10843682	Vitamin D3 up-regulated protein 1 mediates oxidative stress via suppressing the thioredoxin function.

Q5RHR6	BROMI_DANRE	Protein broad-minded	20159594	Broad-minded links cell cycle-related kinase to cilia assembly and hedgehog signal transduction.

Q13263	TIF1B_HUMAN	Transcription intermediary factor 1-beta	10330177	KAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: a potential role for Kruppel-associated box-zinc finger proteins in heterochromatin- mediated gene silencing.

O43007	C1TM_SCHPO	C-1-tetrahydrofolate synthase, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q7Z460	CLAP1_HUMAN	CLIP-associating protein 1	12837247	Human CLASP1 is an outer kinetochore component that regulates spindle microtubule dynamics.

O95470	SGPL1_HUMAN	Sphingosine-1-phosphate lyase 1	11018465	Human sphingosine-1-phosphate lyase: cDNA cloning, functional expression studies and mapping to chromosome 10q22.

P53330	RT102_YEAST	Regulator of Ty1 transposition protein 102	14729968	The ctf13-30/CTF13 genomic haploinsufficiency modifier screen identifies the yeast chromatin remodeling complex RSC, which is required for the establishment of sister chromatid cohesion.

Q922J9	FACR1_MOUSE	Fatty acyl-CoA reductase 1	15220348	Mammalian wax biosynthesis: I. Identification of two fatty acyl- coenzyme A reductases with different substrate specificities and tissue distributions.

Q96T83	SL9A7_HUMAN	Sodium/hydrogen exchanger 7	11279194	Molecular cloning and characterization of a novel (Na+,K+)/H+ exchanger localized to the trans-Golgi network.

P31574	FIXB_ECOLI	Protein fixB	12081978	The fixA and fixB genes are necessary for anaerobic carnitine reduction in Escherichia coli.

Q8LDC8	ERF92_ARATH	Ethylene-responsive transcription factor 1B	9851977	Nuclear events in ethylene signaling: a transcriptional cascade mediated by ETHYLENE-INSENSITIVE3 and ETHYLENE-RESPONSE-FACTOR1.

P21549	SPYA_HUMAN	Serine--pyruvate aminotransferase	12899834	Crystal structure of alanine:glyoxylate aminotransferase and the relationship between genotype and enzymatic phenotype in primary hyperoxaluria type 1.

Q17308	TRA1_CAEBR	Sex-determining transformer protein 1	11250902	The TRA-1 transcription factor binds TRA-2 to regulate sexual fates in Caenorhabditis elegans.

P69428	TATA_ECOLI	Sec-independent protein translocase protein tatA	12427031	Characterization and membrane assembly of the TatA component of the Escherichia coli twin-arginine protein transport system.

P42345	MTOR_HUMAN	Serine/threonine-protein kinase mTOR	18925875	mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1).

P53331	REXO1_YEAST	RNA exonuclease 1	10716935	Three conserved members of the RNase D family have unique and overlapping functions in the processing of 5S, 5.8S, U4, U5, RNase MRP and RNase P RNAs in yeast.

Q9PTD7	CING_XENLA	Cingulin	11682052	Cingulin interacts with F-actin in vitro.

P13686	PPA5_HUMAN	Tartrate-resistant acid phosphatase type 5	8359686	Isolation and characterization of the genes encoding mouse and human type-5 acid phosphatase.

O46077	OR2A_DROME	Odorant receptor 2a	10458908	Identification of candidate Drosophila olfactory receptors from genomic DNA sequence.

Q94B60	CLPP4_ARATH	ATP-dependent Clp protease proteolytic subunit 4, chloroplastic	11278690	Identification of a 350-kDa ClpP protease complex with 10 different Clp isoforms in chloroplasts of Arabidopsis thaliana.

Q99NB7	ACO12_RAT	Acyl-coenzyme A thioesterase 12	11322891	Molecular cloning and functional expression of rat liver cytosolic acetyl-CoA hydrolase.

O14130	YF54_SCHPO	Uncharacterized transcriptional regulatory protein C3C7.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q92529	SHC3_HUMAN	SHC-transforming protein 3	8808684	N-Shc: a neural-specific adapter molecule that mediates signaling from neurotrophin/Trk to Ras/MAPK pathway.

P19823	ITIH2_HUMAN	Inter-alpha-trypsin inhibitor heavy chain H2	2476436	Analysis of inter-alpha-trypsin inhibitor and a novel trypsin inhibitor, pre-alpha-trypsin inhibitor, from human plasma. Polypeptide chain stoichiometry and assembly by glycan.

P33205	FXA4A_XENLA	Forkhead box protein A4-A	15128667	Patterning the forebrain: FoxA4a/Pintallavis and Xvent2 determine the posterior limit of Xanf1 expression in the neural plate.

P36873	PP1G_HUMAN	Serine/threonine-protein phosphatase PP1-gamma catalytic subunit	19377461	GlcNAcylation of a histone methyltransferase in retinoic-acid-induced granulopoiesis.

Q91XU0	WRIP1_MOUSE	ATPase WRNIP1	11301316	A novel protein interacts with the Werner's syndrome gene product physically and functionally.

Q9FZD1	PPR58_ARATH	Pentatricopeptide repeat-containing protein At1g26460, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q9UUD2	PRP38_SCHPO	Pre-mRNA-splicing factor 38	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P25156	PSA_THEAC	Proteasome subunit alpha	8999862	Processive degradation of proteins and other catalytic properties of the proteasome from Thermoplasma acidophilum.

Q13838	UAP56_HUMAN	Spliceosome RNA helicase BAT1	7601445	The BAT1 gene in the MHC encodes an evolutionarily conserved putative nuclear RNA helicase of the DEAD family.

Q9LEH3	PER15_IPOBA	Peroxidase 15	17936696	Purification, cloning and characterization of a novel peroxidase isozyme from sweetpotatoes (Ipomoea batatas).

Q80V62	FACD2_MOUSE	Fanconi anemia group D2 protein homolog	12893777	Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice.

Q17635	NDC80_CAEEL	Kinetochore protein ndc-80	14522947	KNL-1 directs assembly of the microtubule-binding interface of the kinetochore in C. elegans.

P70269	CATE_MOUSE	Cathepsin E	9180269	Cloning, expression and characterisation of murine procathepsin E.

Q62658	FKB1A_RAT	Peptidyl-prolyl cis-trans isomerase FKBP1A	9013543	Cyclic ADP-ribose binds to FK506-binding protein 12.6 to release Ca2+ from islet microsomes.

P38626	NCB5R_YEAST	NADH-cytochrome b5 reductase 1	14930	Studies on the microsomal electron-transport system of anaerobically grown yeast. IV. Purification and characterization of NADH-cytochrome b5 reductase.

P55852	SUMO1_ARATH	Small ubiquitin-related modifier 1	20521085	Sumoylation of Arabidopsis heat shock factor A2 (HsfA2) modifies its activity during acquired thermotholerance.

Q96ED9	HOOK2_HUMAN	Protein Hook homolog 2	9927460	Genetic analysis of hook, a gene required for endocytic trafficking in Drosophila.

Q99MR0	ACL6B_MOUSE	Actin-like protein 6B	12368262	Identification of a polymorphic, neuron-specific chromatin remodeling complex.

Q9EPQ2	RPGR1_MOUSE	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1	11104772	Retinitis pigmentosa GTPase regulator (RPGR)-interacting protein is stably associated with the photoreceptor ciliary axoneme and anchors RPGR to the connecting cilium.

Q9SCY0	PGMP_ARATH	Phosphoglucomutase, chloroplastic	10759515	The plastidic phosphoglucomutase from Arabidopsis. A reversible enzyme reaction with an important role in metabolic control.

Q9M4A1	SPO12_ARATH	Meiotic recombination protein SPO11-2	17018031	Arabidopsis SPO11-2 functions with SPO11-1 in meiotic recombination.

P09917	LOX5_HUMAN	Arachidonate 5-lipoxygenase	3422434	Cloning of the cDNA for human 5-lipoxygenase.

O80634	PPL2_ARATH	PsbP-like protein 2, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

O65154	KIWI_ARATH	RNA polymerase II transcriptional coactivator KIWI	9681033	Isolation of putative plant transcriptional coactivators using a modified two-hybrid system incorporating a GFP reporter gene.

Q13310	PABP4_HUMAN	Polyadenylate-binding protein 4	9030741	Identification and structure of activated-platelet protein-1, a protein with RNA-binding domain motifs that is expressed by activated platelets.

P26196	DDX6_HUMAN	Probable ATP-dependent RNA helicase DDX6	1579499	Cloning, expression and localization of an RNA helicase gene from a human lymphoid cell line with chromosomal breakpoint 11q23.3.

Q02884	ELP4_YEAST	Elongator complex protein 4	11689709	Characterization of a six-subunit holo-elongator complex required for the regulated expression of a group of genes in Saccharomyces cerevisiae.

Q9URY4	YI01_SCHPO	Putative amidase C869.01	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q04052	ARO80_YEAST	Transcriptional activator ARO80	10207060	Transcriptional induction by aromatic amino acids in Saccharomyces cerevisiae.

P37702	BGL38_ARATH	Myrosinase 1	19703694	Myrosinases from root and leaves of Arabidopsis thaliana have different catalytic properties.

Q92778	PBCG_MESAU	Pancreatic beta cell growth factor	9151782	Cloning and sequencing of the pancreatic islet neogenesis associated protein (INGAP) gene and its expression in islet neogenesis in hamsters.

Q9UEW3	MARCO_HUMAN	Macrophage receptor MARCO	9468508	Structure of the human macrophage MARCO receptor and characterization of its bacteria-binding region.

P46414	CDN1B_MOUSE	Cyclin-dependent kinase inhibitor 1B	19767775	Lysine 269 is essential for cyclin D1 ubiquitylation by the SCF(Fbx4/alphaB-crystallin) ligase and subsequent proteasome-dependent degradation.

P54252	ATX3_HUMAN	Ataxin-3	9580663	Ataxin-3 is transported into the nucleus and associates with the nuclear matrix.

Q13501	SQSTM_HUMAN	Sequestosome-1	12857745	Structure of the ubiquitin-associated domain of p62 (SQSTM1) and implications for mutations that cause Paget's disease of bone.

P09959	SWI6_YEAST	Regulatory protein SWI6	12697814	Cell cycle activation of the Swi6p transcription factor is linked to nucleocytoplasmic shuttling.

P46985	MNN11_YEAST	Probable alpha-1,6-mannosyltransferase MNN11	9430634	Multi-protein complexes in the cis Golgi of Saccharomyces cerevisiae with alpha-1,6-mannosyltransferase activity.

P27680	COQ3_YEAST	Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial	10419476	Yeast and rat Coq3 and Escherichia coli UbiG polypeptides catalyze both O-methyltransferase steps in coenzyme Q biosynthesis.

P50402	EMD_HUMAN	Emerin	17785515	A novel role for the nuclear membrane protein emerin in association of the centrosome to the outer nuclear membrane.

P40061	TSC11_YEAST	Target of rapamycin complex 2 subunit TSC11	15809876	Saccharomyces cerevisiae TSC11/AVO3 participates in regulating cell integrity and functionally interacts with components of the Tor2 complex.

O60879	DIAP2_HUMAN	Protein diaphanous homolog 2	9497258	A human homologue of the Drosophila melanogaster diaphanous gene is disrupted in a patient with premature ovarian failure: evidence for conserved function in oogenesis and implications for human sterility.

Q12884	SEPR_HUMAN	Seprase	7911242	Molecular cloning of fibroblast activation protein alpha, a member of the serine protease family selectively expressed in stromal fibroblasts of epithelial cancers.

O33245	PSB_MYCTU	Proteasome subunit beta	18059281	In vivo gene silencing identifies the Mycobacterium tuberculosis proteasome as essential for the bacteria to persist in mice.

Q90VV1	HES4B_XENLA	Transcription factor HES-4-B	16316406	Hairy is a cell context signal controlling Notch activity.

Q9QZN4	FBX6_MOUSE	F-box only protein 6	15723043	Glycoprotein-specific ubiquitin ligases recognize N-glycans in unfolded substrates.

Q9H307	PININ_HUMAN	Pinin	10809736	Dissection of protein linkage between keratins and pinin, a protein with dual location at desmosome-intermediate filament complex and in the nucleus.

Q4ADV8	CKX2_ORYSJ	Cytokinin dehydrogenase 2	15976269	Cytokinin oxidase regulates rice grain production.

P79011	T2EB_SCHPO	Transcription initiation factor IIE subunit beta	15743411	Studies of Schizosaccharomyces pombe TFIIE indicate conformational and functional changes in RNA polymerase II at transcription initiation.

P39001	UME6_YEAST	Transcriptional regulatory protein UME6	8628320	Induction of meiosis in Saccharomyces cerevisiae depends on conversion of the transcriptional represssor Ume6 to a positive regulator by its regulated association with the transcriptional activator Ime1.

Q60760	GRB10_MOUSE	Growth factor receptor-bound protein 10	15664450	Distinct Grb10 domain requirements for effects on glucose uptake and insulin signaling.

P23514	COPB_RAT	Coatomer subunit beta	18556652	Scyl1, mutated in a recessive form of spinocerebellar neurodegeneration, regulates COPI-mediated retrograde traffic.

Q6AZZ1	TRI68_HUMAN	E3 ubiquitin-protein ligase TRIM68	18451177	TRIM68 regulates ligand-dependent transcription of androgen receptor in prostate cancer cells.

Q80W99	CTSR3_MOUSE	Cation channel sperm-associated protein 3	17227845	All four CatSper ion channel proteins are required for male fertility and sperm cell hyperactivated motility.

Q96IQ7	VSIG2_HUMAN	V-set and immunoglobulin domain-containing protein 2	9862345	CTX, a Xenopus thymocyte receptor, defines a molecular family conserved throughout vertebrates.

P28872	CARP1_CANAL	Candidapepsin-1	9043112	Analysis of secreted aspartic proteinases from Candida albicans: purification and characterization of individual Sap1, Sap2 and Sap3 isoenzymes.

P41734	IAH1_YEAST	Isoamyl acetate-hydrolyzing esterase	10855721	Purification and characterization of isoamyl acetate-hydrolyzing esterase encoded by the IAH1 gene of Saccharomyces cerevisiae from a recombinant Escherichia coli.

P22934	TNR1A_RAT	Tumor necrosis factor receptor superfamily member 1A	11486281	Polymorphisms of the tumor necrosis factor receptor type 1 locus among autoimmune susceptible and resistant inbred rat strains.

Q54JM5	PSMD1_DICDI	26S proteasome non-ATPase regulatory subunit 1	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

Q9YGC3	CXR4A_XENLA	C-X-C chemokine receptor type 4-A	11859124	Xenopus laevis stromal cell-derived factor 1: conservation of structure and function during vertebrate development.

Q62638	GSLG1_RAT	Golgi apparatus protein 1	7768993	MG-160, a membrane sialoglycoprotein of the medial cisternae of the rat Golgi apparatus, binds basic fibroblast growth factor and exhibits a high level of sequence identity to a chicken fibroblast growth factor receptor.

Q86V81	THOC4_HUMAN	THO complex subunit 4	19165146	Adaptor Aly and co-adaptor Thoc5 function in the Tap-p15-mediated nuclear export of HSP70 mRNA.

P51657	DHB1_RAT	Estradiol 17-beta-dehydrogenase 1	8612487	Cloning of rat 17 beta-hydroxysteroid dehydrogenase type 2 and characterization of tissue distribution and catalytic activity of rat type 1 and type 2 enzymes.

Q8CIZ5	DMBT1_RAT	Deleted in malignant brain tumors 1 protein	11121438	Induction of terminal differentiation in epithelial cells requires polymerization of hensin by galectin 3.

P30429	CED4_CAEEL	Cell death protein 4	8706125	An alternatively spliced C. elegans ced-4 RNA encodes a novel cell death inhibitor.

P11633	NHP6B_YEAST	Non-histone chromosomal protein 6B	8946917	Yeast HMG proteins NHP6A/B potentiate promoter-specific transcriptional activation in vivo and assembly of preinitiation complexes in vitro.

Q04007	YDR86_YEAST	Uncharacterized protein YDR186C	14562095	Global analysis of protein localization in budding yeast.

Q12904	AIMP1_HUMAN	Aminoacyl tRNA synthase complex-interacting multifunctional protein 1	11306575	The EMAPII cytokine is released from the mammalian multisynthetase complex after cleavage of its p43/proEMAPII component.

Q92374	RFA3_SCHPO	Replication factor A protein 3	8702843	Purification, gene cloning, and reconstitution of the heterotrimeric single-stranded DNA-binding protein from Schizosaccharomyces pombe.

P38703	LAG1_YEAST	Sphingosine N-acyltransferase LAG1	14562095	Global analysis of protein localization in budding yeast.

Q9ZVD0	SRRT_ARATH	Serrate RNA effector molecule	16889646	SERRATE is a novel nuclear regulator in primary microRNA processing in Arabidopsis.

Q61235	SNTB2_MOUSE	Beta-2-syntrophin	10404183	Interactions between beta 2-syntrophin and a family of microtubule- associated serine/threonine kinases.

Q9H4A6	GOLP3_HUMAN	Golgi phosphoprotein 3	19553991	GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer.

Q12280	IQG1_YEAST	Ras GTPase-activating-like protein IQG1	12446742	Iqg1p links spatial and secretion landmarks to polarity and cytokinesis.

Q12366	NDJ1_YEAST	Non-disjunction protein 1	17495028	MPS3 mediates meiotic bouquet formation in Saccharomyces cerevisiae.

Q9EPA0	DRP2_RAT	Dystrophin-related protein 2	11083927	Association of dystrophin-related protein 2 (DRP2) with postsynaptic densities in rat brain.

Q12380	ATG5_YEAST	Autophagy protein 5	11689437	The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation.

Q9NPG3	UBN1_HUMAN	Ubinuclein-1	10725330	Ubinuclein, a novel nuclear protein interacting with cellular and viral transcription factors.

O88509	DNM3B_MOUSE	DNA (cytosine-5)-methyltransferase 3B	11919202	Molecular enzymology of the catalytic domains of the Dnmt3a and Dnmt3b DNA methyltransferases.

P49750	YLPM1_HUMAN	YLP motif-containing protein 1	17890166	The nuclear PP1 interacting protein ZAP3 (ZAP) is a putative nucleoside kinase that complexes with SAM68, CIA, NF110/45, and HNRNP- G.

Q6X1Y6	ACCN3_MOUSE	Amiloride-sensitive cation channel 3	12060708	A role for ASIC3 in the modulation of high-intensity pain stimuli.

O60333	KIF1B_HUMAN	Kinesin-like protein KIF1B	16225668	The novel protein KBP regulates mitochondria localization by interaction with a kinesin-like protein.

Q12530	RMP1_YEAST	Ribonuclease MRP protein subunit RMP1	14562095	Global analysis of protein localization in budding yeast.

O17695	HDA1_CAEEL	Histone deacetylase 1	11940660	Functional requirement for histone deacetylase 1 in Caenorhabditis elegans gonadogenesis.

Q63755	PRDM2_RAT	PR domain zinc finger protein 2	7538672	The retinoblastoma protein binds to RIZ, a zinc-finger protein that shares an epitope with the adenovirus E1A protein.

P35689	ERCC5_MOUSE	DNA repair protein complementing XP-G cells homolog	7510366	An ERCC5 gene with homology to yeast RAD2 is involved in group G Xeroderma pigmentosum.

O13988	POT1_SCHPO	Protection of telomeres protein 1	18535244	Fission yeast Pot1-Tpp1 protects telomeres and regulates telomere length.

Q9U8Q1	TGRD1_DICDI	Tiger protein D1	19285397	Polymorphic members of the lag gene family mediate kin discrimination in Dictyostelium.

P48994	TRPL_DROME	Transient-receptor-potential-like protein	10371201	Ca2+-dependent interaction of the trpl cation channel and calmodulin.

P23321	PSBO1_ARATH	Oxygen-evolving enhancer protein 1-1, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q17802	CPG1_CAEEL	Chondroitin proteoglycan 1	16785326	Identification of novel chondroitin proteoglycans in Caenorhabditis elegans: embryonic cell division depends on CPG-1 and CPG-2.

Q8BZZ3	WWP1_MOUSE	NEDD4-like E3 ubiquitin-protein ligase WWP1	19561640	WW domain containing E3 ubiquitin protein ligase 1 targets the full- length ErbB4 for ubiquitin-mediated degradation in breast cancer.

P52800	EFNB2_MOUSE	Ephrin-B2	11780069	Crystal structure of an Eph receptor-ephrin complex.

P34308	CAN_CAEEL	Calpain clp-1	12410314	Specific aspartyl and calpain proteases are required for neurodegeneration in C. elegans.

O88895	HDAC3_MOUSE	Histone deacetylase 3	12130660	Tissue-specific regulation of retinal and pituitary precursor cell proliferation.

O94483	HOS3_SCHPO	High osmolarity sensitivity protein 3	10879493	Identification and characterization of a novel gene, hos3+, the function of which is necessary for growth under high osmotic stress in fission yeast.

P38132	MCM7_YEAST	DNA replication licensing factor MCM7	7708676	Cell cycle-regulated nuclear import and export of Cdc47, a protein essential for initiation of DNA replication in budding yeast.

Q1ZXH8	GXCDD_DICDI	Guanine exchange factor for Rac 30	17584488	GxcDD, a putative RacGEF, is involved in Dictyostelium development.

Q63470	DYR1A_RAT	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	8631952	Dyrk, a dual specificity protein kinase with unique structural features whose activity is dependent on tyrosine residues between subdomains VII and VIII.

Q09874	YAGB_SCHPO	Uncharacterized protein C12G12.11c	14655046	Two-hybrid search for proteins that interact with Sad1 and Kms1, two membrane-bound components of the spindle pole body in fission yeast.

Q02908	ELP3_YEAST	Elongator complex protein 3	10445034	A novel histone acetyltransferase is an integral subunit of elongating RNA polymerase II holoenzyme.

Q9JIF3	GTR8_MOUSE	Solute carrier family 2, facilitated glucose transporter member 8	10821868	GLUT8, a novel member of the sugar transport facilitator family with glucose transport activity.

Q058N4	MRS2B_ARATH	Magnesium transporter MRS2-11, chloroplastic	12938931	Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis.

P78344	IF4G2_HUMAN	Eukaryotic translation initiation factor 4 gamma 2	11943866	The caspase-cleaved DAP5 protein supports internal ribosome entry site-mediated translation of death proteins.

Q16650	TBR1_HUMAN	T-box brain protein 1	7619531	T-brain-1: a homolog of Brachyury whose expression defines molecularly distinct domains within the cerebral cortex.

Q09161	NCBP1_HUMAN	Nuclear cap-binding protein subunit 1	18369367	NMD resulting from encephalomyocarditis virus IRES-directed translation initiation seems to be restricted to CBP80/20-bound mRNA.

Q9SU14	NUDT7_ARATH	Nudix hydrolase 7	16328543	Analysis of Arabidopsis growth factor gene 1 (GFG1) encoding a nudix hydrolase during oxidative signaling.

Q8BH00	AL8A1_MOUSE	Aldehyde dehydrogenase family 8 member A1	12519776	Mouse retinal dehydrogenase 4 (RALDH4), molecular cloning, cellular expression, and activity in 9-cis-retinoic acid biosynthesis in intact cells.

Q04121	NHX1_YEAST	Endosomal/prevacuolar sodium/hydrogen exchanger	10589731	The yeast endosomal Na+/H+ exchanger, Nhx1, confers osmotolerance following acute hypertonic shock.

Q86YW5	TRML1_HUMAN	Trem-like transcript 1 protein	15128762	TREM-like transcript-1, a platelet immunoreceptor tyrosine-based inhibition motif encoding costimulatory immunoreceptor that enhances, rather than inhibits, calcium signaling via SHP-2.

Q64279	HAND1_MOUSE	Heart- and neural crest derivatives-expressed protein 1	17891141	Nucleolar release of Hand1 acts as a molecular switch to determine cell fate.

Q15562	TEAD2_HUMAN	Transcriptional enhancer factor TEF-4	8702974	A novel family of developmentally regulated mammalian transcription factors containing the TEA/ATTS DNA binding domain.

P20840	SAG1_YEAST	Alpha-agglutinin	2677666	AG alpha 1 is the structural gene for the Saccharomyces cerevisiae alpha-agglutinin, a cell surface glycoprotein involved in cell-cell interactions during mating.

P41180	CASR_HUMAN	Extracellular calcium-sensing receptor	7874174	Autosomal dominant hypocalcaemia caused by a Ca(2+)-sensing receptor gene mutation.

P40995	SCD1_SCHPO	Rho guanine nucleotide exchange factor scd1	9892665	Moe1, a conserved protein in Schizosaccharomyces pombe, interacts with a Ras effector, Scd1, to affect proper spindle formation.

P32465	HXT1_YEAST	Low-affinity glucose transporter HXT1	2046678	The HXT1 gene product of Saccharomyces cerevisiae is a new member of the family of hexose transporters.

O35437	TCF21_MOUSE	Transcription factor 21	9545521	Capsulin: a novel bHLH transcription factor expressed in epicardial progenitors and mesenchyme of visceral organs.

O00358	FOXE1_HUMAN	Forkhead box protein E1	9169137	FKHL15, a new human member of the forkhead gene family located on chromosome 9q22.

Q24134	NELFD_DROME	Negative elongation factor D	12782658	NELF and DSIF cause promoter proximal pausing on the hsp70 promoter in Drosophila.

P08581	MET_HUMAN	Hepatocyte growth factor receptor	3325883	Primary structure of the met protein tyrosine kinase domain.

Q08237	REXO4_YEAST	RNA exonuclease 4	14562095	Global analysis of protein localization in budding yeast.

P35206	CSG2_YEAST	Mannosyl phosphorylinositol ceramide synthase regulatory protein CSG2	12954640	Csg1p and newly identified Csh1p function in mannosylinositol phosphorylceramide synthesis by interacting with Csg2p.

Q940H6	SRK2E_ARATH	Serine/threonine-protein kinase SRK2E	15064385	Cytoplasmic alkalization precedes reactive oxygen species production during methyl jasmonate- and abscisic acid-induced stomatal closure.

P61203	CSN2_RAT	COP9 signalosome complex subunit 2	12524175	Implication of Trip15/CSN2 in early stage of neuronal differentiation of P19 embryonal carcinoma cells.

Q9Z2E3	ERN2_MOUSE	Serine/threonine-protein kinase/endoribonuclease IRE2	9755171	Cloning of mammalian Ire1 reveals a diversity in the ER stress responses.

Q9HBE1	PATZ1_HUMAN	POZ-, AT hook-, and zinc finger-containing protein 1	10713105	A novel member of the BTB/POZ family, PATZ, associates with the RNF4 RING finger protein and acts as a transcriptional repressor.

P41920	YRB1_YEAST	Ran-specific GTPase-activating protein 1	7489726	Mutants in a yeast Ran binding protein are defective in nuclear transport.

Q8R0Z6	ANGL6_MOUSE	Angiopoietin-related protein 6	12871997	Angiopoietin-related growth factor (AGF) promotes epidermal proliferation, remodeling, and regeneration.

P33122	TYE7_YEAST	Serine-rich protein TYE7	10606743	The E-box DNA binding protein Sgc1p suppresses the gcr2 mutation, which is involved in transcriptional activation of glycolytic genes in Saccharomyces cerevisiae.

P20591	MX1_HUMAN	Interferon-induced GTP-binding protein Mx1	15757897	MxA, a member of the dynamin superfamily, interacts with the ankyrin- like repeat domain of TRPC.

P97411	ICA69_MOUSE	Islet cell autoantigen 1	11029035	The diabetes autoantigen ICA69 and its Caenorhabditis elegans homologue, ric-19, are conserved regulators of neuroendocrine secretion.

O13848	I3ACR_SCHPO	NAD/NADP-dependent indole-3-acetaldehyde reductase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q92876	KLK6_HUMAN	Kallikrein-6	12016211	The structure of human prokallikrein 6 reveals a novel activation mechanism for the kallikrein family.

P48527	SYYM_YEAST	Tyrosyl-tRNA synthetase, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q08032	CDC45_YEAST	Cell division control protein 45	15201046	Mcm10 and Cdc45 cooperate in origin activation in Saccharomyces cerevisiae.

P09615	WNTG_DROME	Protein wingless	18193037	Wingless secretion requires endosome-to-Golgi retrieval of Wntless/Evi/Sprinter by the retromer complex.

O13821	VPS27_SCHPO	Vacuolar protein sorting-associated protein 27	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O02372	OB76A_DROME	General odorant-binding protein lush	14759510	Revisiting the odorant-binding protein LUSH of Drosophila melanogaster: evidence for odour recognition and discrimination.

Q03124	RSC9_YEAST	Chromatin structure-remodeling complex subunit RSC9	10619019	Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains.

P20722	BMP6_MOUSE	Bone morphogenetic protein 6	14623234	Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot.

P85051	DYR1A_RABIT	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	11311120	The kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation site.

Q6RZZ9	KIF13_DICDI	Kinesin-related protein 13	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

Q9UUE5	NUP85_SCHPO	Nucleoporin nup85	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O08623	SQSTM_RAT	Sequestosome-1	10477520	Differential stimulation of PKC phosphorylation of potassium channels by ZIP1 and ZIP2.

P52697	6PGL_ECOLI	6-phosphogluconolactonase	15576773	Identification of the Escherichia coli K-12 ybhE gene as pgl, encoding 6-phosphogluconolactonase.

Q9UUB0	RT17_SCHPO	40S ribosomal protein S17, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O22049	AOX2_ARATH	Alternative oxidase 2, mitochondrial	11434463	The gene for alternative oxidase-2 (AOX2) from Arabidopsis thaliana consists of five exons unlike other AOX genes and is transcribed at an early stage during germination.

Q02887	ATG21_YEAST	Autophagy-related protein 21	15194695	Atg21 is required for effective recruitment of Atg8 to the preautophagosomal structure during the Cvt pathway.

Q7TPV4	MBB1A_MOUSE	Myb-binding protein 1A	12941609	Myb-binding protein 1a is a nucleocytoplasmic shuttling protein that utilizes CRM1-dependent and independent nuclear export pathways.

Q5T2D2	TRML2_HUMAN	Trem-like transcript 2 protein	18650384	Triggering receptor expressed on myeloid cell-like transcript 2 (TLT- 2) is a counter-receptor for B7-H3 and enhances T cell responses.

O04147	CPD_ARATH	Cyclic phosphodiesterase	9148938	Cloning and characterization of the Arabidopsis cyclic phosphodiesterase which hydrolyzes ADP-ribose 1'',2''-cyclic phosphate and nucleoside 2',3'-cyclic phosphates.

P53923	CTU2_YEAST	Cytoplasmic tRNA 2-thiolation protein 2	19145231	Ubiquitin-related modifier Urm1 acts as a sulphur carrier in thiolation of eukaryotic transfer RNA.

Q14129	DGCR6_HUMAN	Protein DGCR6	8733130	Isolation of a novel gene from the DiGeorge syndrome critical region with homology to Drosophila gdl and to human LAMC1 genes.

P22217	TRX1_YEAST	Thioredoxin-1	2026619	Thioredoxin deficiency in yeast prolongs S phase and shortens the G1 interval of the cell cycle.

Q9BXX3	AN30A_HUMAN	Ankyrin repeat domain-containing protein 30A	11280766	Identification of a tissue-specific putative transcription factor in breast tissue by serological screening of a breast cancer library.

P53154	GUP1_YEAST	Glycerol uptake protein 1	10931309	GUP1 and its close homologue GUP2, encoding multimembrane-spanning proteins involved in active glycerol uptake in Saccharomyces cerevisiae.

Q9ULV5	HSF4_HUMAN	Heat shock factor protein 4	8972228	HSF4, a new member of the human heat shock factor family which lacks properties of a transcriptional activator.

O88329	MYO1A_MOUSE	Myosin-Ia	9933937	Cloning and characterization of mouse brush border myosin-I in adult and embryonic intestine.

Q06168	SFH1_YEAST	Chromatin structure-remodeling complex subunit SFH1	9154831	Sfh1p, a component of a novel chromatin-remodeling complex, is required for cell cycle progression.

P54843	MAF_MOUSE	Transcription factor Maf	15249232	Developmental contribution of c-maf in the kidney: distribution and developmental study of c-maf mRNA in normal mice kidney and histological study of c-maf knockout mice kidney and liver.

P36578	RL4_HUMAN	60S ribosomal protein L4	8268230	Human ribosomal protein L4: cloning and sequencing of the cDNA and primary structure of the protein.

Q8K3Y3	LN28A_MOUSE	Protein lin-28 homolog A	17473174	Lin-28 binds IGF-2 mRNA and participates in skeletal myogenesis by increasing translation efficiency.

Q06413	MEF2C_HUMAN	Myocyte-specific enhancer factor 2C	8455629	hMEF2C gene encodes skeletal muscle- and brain-specific transcription factors.

O16000	STX1A_CAEEL	Syntaxin-1A homolog	1945043	Additional genes which result in an elevation of acetylcholine levels by mutations in Caenorhabditis elegans.

Q99M75	RTN4R_RAT	Reticulon-4 receptor	12037567	Nogo-66 receptor antagonist peptide promotes axonal regeneration.

P33724	CAV1_CANFA	Caveolin-1	8385608	Caveolae and sorting in the trans-Golgi network of epithelial cells.

P78847	NU186_SCHPO	Nucleoporin nup186	15116432	Identification of genes encoding putative nucleoporins and transport factors in the fission yeast Schizosaccharomyces pombe: a deletion analysis.

P78847	NU186_SCHPO	Nucleoporin nup186	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q13042	CDC16_HUMAN	Cell division cycle protein 16 homolog	16364912	Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C.

P27614	CBPS_YEAST	Carboxypeptidase S	2026161	Carboxypeptidase yscS: gene structure and function of the vacuolar enzyme.

Q804T6	DIXC1_DANRE	Dixin	12526749	Ccd1, a novel protein with a DIX domain, is a positive regulator in the Wnt signaling during zebrafish neural patterning.

P29353	SHC1_HUMAN	SHC-transforming protein 1	1623525	A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction.

P40986	CDC1_YEAST	Cell division control protein 1	7969142	Mutations in the Saccharomyces cerevisiae CDC1 gene affect double- strand-break-induced intrachromosomal recombination.

P32623	CRH2_YEAST	Probable glycosidase CRH2	12045225	Mechanisms for targeting of the Saccharomyces cerevisiae GPI-anchored cell wall protein Crh2p to polarised growth sites.

P51179	NR4A3_RAT	Nuclear receptor subfamily 4 group A member 3	7556683	NOR-2 (neuron-derived orphan receptor), a brain zinc finger protein, is highly induced during liver regeneration.

Q05867	YL283_YEAST	Uncharacterized protein YLR283W, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

Q92355	SEN1_SCHPO	Helicase sen1	10545196	The sen1(+) gene of Schizosaccharomyces pombe, a homologue of budding yeast SEN1, encodes an RNA and DNA helicase.

P32641	RAD24_YEAST	Checkpoint protein RAD24	10913172	Rfc5, in cooperation with rad24, controls DNA damage checkpoints throughout the cell cycle in Saccharomyces cerevisiae.

Q9JIL9	NBN_RAT	Nibrin	10908350	The MRE11-NBS1-RAD50 pathway is perturbed in SV40 large T antigen- immortalized AT-1, AT-2 and HL-1 cardiomyocytes.

Q9QZ23	NFU1_MOUSE	NFU1 iron-sulfur cluster scaffold homolog, mitochondrial	12915448	The Lafora disease gene product laforin interacts with HIRIP5, a phylogenetically conserved protein containing a NifU-like domain.

Q12488	PSF1_YEAST	DNA replication complex GINS protein PSF1	12730134	GINS, a novel multiprotein complex required for chromosomal DNA replication in budding yeast.

Q7KTH8	CSN8_DROME	COP9 signalosome complex subunit 8	12737805	The COP9 signalosome promotes degradation of Cyclin E during early Drosophila oogenesis.

Q16514	TAF12_HUMAN	Transcription initiation factor TFIID subunit 12	7729427	Cloning and characterization of hTAFII18, hTAFII20 and hTAFII28: three subunits of the human transcription factor TFIID.

P82805	TO204_ARATH	Mitochondrial import receptor subunit TOM20-4	11161051	Purification and characterization of the preprotein translocase of the outer mitochondrial membrane from Arabidopsis. Identification of multiple forms of TOM20.

Q16877	F264_HUMAN	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4	10095107	Cloning, expression and chromosomal localization of a human testis 6- phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene.

Q16270	IBP7_HUMAN	Insulin-like growth factor-binding protein 7	8117260	Cell adhesion activity of a 30-kDa major secreted protein from human bladder carcinoma cells.

P42681	TXK_HUMAN	Tyrosine-protein kinase TXK	7951233	TXK, a novel human tyrosine kinase expressed in T cells shares sequence identity with Tec family kinases and maps to 4p12.

Q969S8	HDA10_HUMAN	Histone deacetylase 10	11739383	Isolation and characterization of a novel class II histone deacetylase, HDAC10.

P54108	CRIS3_HUMAN	Cysteine-rich secretory protein 3	8601434	SGP28, a novel matrix glycoprotein in specific granules of human neutrophils with similarity to a human testis-specific gene product and a rodent sperm-coating glycoprotein.

P25443	RS2_YEAST	40S ribosomal protein S2	15590835	The small-subunit processome is a ribosome assembly intermediate.

P81829	LCK_DROME	Leucokinin	10574744	Isolation and characterization of a leucokinin-like peptide of Drosophila melanogaster.

Q63525	NUDC_RAT	Nuclear migration protein nudC	9601647	The lissenchephaly gene product Lis1, a protein involved in neuronal migration, interacts with a nuclear movement protein, NudC.

Q9H2X9	S12A5_HUMAN	Solute carrier family 12 member 5	12106695	Molecular, functional, and genomic characterization of human KCC2, the neuronal K-Cl cotransporter.

Q05905	YL301_YEAST	Uncharacterized protein YLR301W	12518317	Identification of novel protein-protein interactions at the cytosolic surface of the Sec63 complex in the yeast ER membrane.

Q02297	NRG1_HUMAN	Pro-neuregulin-1, membrane-bound isoform	1350381	Identification of heregulin, a specific activator of p185erbB2.

Q4H4B6	SCRIB_DANRE	Protein scribble homolog	15829519	Dual roles of zygotic and maternal Scribble1 in neural migration and convergent extension movements in zebrafish embryos.

Q54TH8	TCPG_DICDI	T-complex protein 1 subunit gamma	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P53201	SWC4_YEAST	SWR1-complex protein 4	14645854	ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex.

P39008	POP2_YEAST	Poly(A) ribonuclease POP2	11410650	The yeast POP2 gene encodes a nuclease involved in mRNA deadenylation.

Q9NAN2	PAR6_CAEEL	Partitioning defective protein 6	15151982	PAR-3 is required for epithelial cell polarity in the distal spermatheca of C. elegans.

Q9EPC1	PARVA_MOUSE	Alpha-parvin	11171322	Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily.

P46527	CDN1B_HUMAN	Cyclin-dependent kinase inhibitor 1B	12244303	Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer.

P30304	MPIP1_HUMAN	M-phase inducer phosphatase 1	12399544	Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints.

O94538	SNU66_SCHPO	U4/U6.U5 tri-snRNP-associated protein snu66	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P30793	GCH1_HUMAN	GTP cyclohydrolase 1	3753653	The application of 8-aminoguanosine triphosphate, a new inhibitor of GTP cyclohydrolase I, to the purification of the enzyme from human liver.

Q9Y5E9	PCDBE_HUMAN	Protocadherin beta-14	11322959	The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number.

P15204	THAA_XENLA	Thyroid hormone receptor alpha-A	2587261	Structure and functional expression of a cloned Xenopus thyroid hormone receptor.

Q9JJG6	TMM47_MOUSE	Transmembrane protein 47	17195181	Expression of TM4SF10, a Claudin/EMP/PMP22 family cell junction protein, during mouse kidney development and podocyte differentiation.

Q8K273	MMGT1_MOUSE	Membrane magnesium transporter 1	18057121	Identification and characterization of a novel family of membrane magnesium transporters, MMgT1 and MMgT2.

Q8CBY1	SMAG1_MOUSE	Protein Smaug homolog 1	16221671	Mammalian Smaug is a translational repressor that forms cytoplasmic foci similar to stress granules.

Q91903	ELAV2_XENLA	ELAV-like protein 2	16199879	The Xenopus ELAV protein ElrB represses Vg1 mRNA translation during oogenesis.

A2VB89	BURS_APIME	Bursicon	15811337	Drosophila molting neurohormone bursicon is a heterodimer and the natural agonist of the orphan receptor DLGR2.

Q86X55	CARM1_HUMAN	Histone-arginine methyltransferase CARM1	15221992	Aberrant expression of CARM1, a transcriptional coactivator of androgen receptor, in the development of prostate carcinoma and androgen-independent status.

P84051	H2A_DROME	Histone H2A	2536150	tRNA derived insertion element in histone gene repeating unit of Drosophila melanogaster.

P18410	SPO7_YEAST	Sporulation-specific protein SPO7	15889145	The yeast lipin Smp2 couples phospholipid biosynthesis to nuclear membrane growth.

Q09849	ARP42_SCHPO	SWI/SNF and RSC complexes subunit arp42	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q62226	SHH_MOUSE	Sonic hedgehog protein	18081866	Mammalian Gup1, a homolog of Saccharomyces cerevisiae glycerol uptake/transporter 1, acts as a negative regulator for N-terminal palmitoylation of Sonic hedgehog.

P42898	MTHR_HUMAN	Methylenetetrahydrofolate reductase	7647779	A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase.

Q9VZU2	HHAT_DROME	Protein-cysteine N-palmitoyltransferase Rasp	11861468	Rasp, a putative transmembrane acyltransferase, is required for Hedgehog signaling.

Q9EQ80	NIF3L_MOUSE	NIF3-like protein 1	11124544	Isolation and characterization of a novel human gene, NIF3L1, and its mouse ortholog, Nif3l1, highly conserved from bacteria to mammals.

P51998	RL4P_YEAST	54S ribosomal protein YmL6, mitochondrial	9151978	Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae.

Q12800	TFCP2_HUMAN	Alpha-globin transcription factor CP2	8035790	One exon of the human LSF gene includes conserved regions involved in novel DNA-binding and dimerization motifs.

Q9UKZ4	TEN1_HUMAN	Teneurin-1	10556288	Epstein-Barr virus-negative boys with non-Hodgkin lymphoma are mutated in the SH2D1A gene, as are patients with X-linked lymphoproliferative disease (XLP).

O00103	UBC11_SCHPO	Ubiquitin-conjugating enzyme E2-20 kDa	9154838	A ubiquitin-conjugating enzyme in fission yeast that is essential for the onset of anaphase in mitosis.

Q99471	PFD5_HUMAN	Prefoldin subunit 5	9792694	MM-1, a novel c-Myc-associating protein that represses transcriptional activity of c-Myc.

P62847	RS24_HUMAN	40S ribosomal protein S24	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

O61365	NACH_DROME	Sodium channel protein Nach	12571352	Drosophila DEG/ENaC pickpocket genes are expressed in the tracheal system, where they may be involved in liquid clearance.

P28742	KIP1_YEAST	Kinesin-like protein KIP1	1618910	Kinesin-related proteins required for assembly of the mitotic spindle.

Q94FY7	TOCC_ARATH	Tocopherol cyclase, chloroplastic	12213958	Isolation of an Arabidopsis mutant lacking vitamin E and identification of a cyclase essential for all tocopherol biosynthesis.

O43808	PM34_HUMAN	Peroxisomal membrane protein PMP34	9874197	Identification and characterization of human PMP34, a protein closely related to the peroxisomal integral membrane protein PMP47 of Candida boidinii.

P40072	SLX8_YEAST	E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX8	17728242	Ubiquitin-dependent proteolytic control of SUMO conjugates.

Q13535	ATR_HUMAN	Serine/threonine-protein kinase ATR	12791985	Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes.

P21127	CD11B_HUMAN	Cell division protein kinase 11B	9750192	Duplication of a genomic region containing the Cdc2L1-2 and MMP21-22 genes on human chromosome 1p36.3 and their linkage to D1Z2.

Q80W85	NPM2_MOUSE	Nucleoplasmin-2	12714744	Roles of NPM2 in chromatin and nucleolar organization in oocytes and embryos.

Q13336	UT1_HUMAN	Urea transporter 1	7989337	Cloning and functional expression of a urea transporter from human bone marrow cells.

P36614	PPE1_SCHPO	Serine/threonine-protein phosphatase ppe1	8387356	Isolation and characterization of the fission yeast protein phosphatase gene ppe1+ involved in cell shape control and mitosis.

P16467	PDC5_YEAST	Pyruvate decarboxylase isozyme 2	2185016	Autoregulation may control the expression of yeast pyruvate decarboxylase structural genes PDC1 and PDC5.

P30414	NKTR_HUMAN	NK-tumor recognition protein	8421688	A cyclophilin-related protein involved in the function of natural killer cells.

P29976	AROF_ARATH	Phospho-2-dehydro-3-deoxyheptonate aldolase 1, chloroplastic	1681544	Differential induction of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase genes in Arabidopsis thaliana by wounding and pathogenic attack.

Q9UUE0	YNZC_SCHPO	UPF0655 protein C17G9.12c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q13563	PKD2_HUMAN	Polycystin-2	10760273	The polycystic kidney disease protein PKD2 interacts with Hax-1, a protein associated with the actin cytoskeleton.

P15308	B4_XENLA	Protein B4	3060404	Expression of a histone H1-like protein is restricted to early Xenopus development.

Q6NS38	ALKB2_HUMAN	Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2	12486230	Reversal of DNA alkylation damage by two human dioxygenases.

P38824	COX23_YEAST	Cytochrome c oxidase-assembly factor COX23, mitochondrial	15145942	COX23, a homologue of COX17, is required for cytochrome oxidase assembly.

P97838	DLGP3_RAT	Disks large-associated protein 3	15207911	Distinct spatiotemporal expression of SAPAP transcripts in the developing rat brain: a novel dendritically localized mRNA.

O60931	CTNS_HUMAN	Cystinosin	9537412	A novel gene encoding an integral membrane protein is mutated in nephropathic cystinosis.

Q9LV87	PEP1_ARATH	Elicitor peptide 1	16785434	An endogenous peptide signal in Arabidopsis activates components of the innate immune response.

C0LGG8	Y5343_ARATH	Probable LRR receptor-like serine/threonine-protein kinase At1g53430	17644812	A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome.

Q03028	ODC1_YEAST	Mitochondrial 2-oxodicarboxylate carrier 1	11013234	Identification in Saccharomyces cerevisiae of two isoforms of a novel mitochondrial transporter for 2-oxoadipate and 2-oxoglutarate.

Q9URY1	PPK16_SCHPO	Serine/threonine-protein kinase ppk16	15821139	Systematic deletion analysis of fission yeast protein kinases.

Q8IX30	SCUB3_HUMAN	Signal peptide, CUB and EGF-like domain-containing protein 3	15234972	A novel secreted, cell-surface glycoprotein containing multiple epidermal growth factor-like repeats and one CUB domain is highly expressed in primary osteoblasts and bones.

P70217	HXD13_MOUSE	Homeobox protein Hox-D13	8978698	Function of the Evx-2 gene in the morphogenesis of vertebrate limbs.

Q6R3K9	YSL2_ARATH	Metal-nicotianamine transporter YSL2	15753101	A putative function for the arabidopsis Fe-Phytosiderophore transporter homolog AtYSL2 in Fe and Zn homeostasis.

P50402	EMD_HUMAN	Emerin	16858403	The inner nuclear membrane protein emerin regulates beta-catenin activity by restricting its accumulation in the nucleus.

Q6PD21	SHB_MOUSE	SH2 domain-containing adapter protein B	8302579	Shb is a ubiquitously expressed Src homology 2 protein.

P83585	FER_SOLAB	Ferredoxin	12620316	Large differences in amino acid sequences among ferredoxins from several species of genus Solanum.

Q8UVJ6	VANG2_DANRE	Vang-like protein 2	10992326	Role of the zebrafish trilobite locus in gastrulation movements of convergence and extension.

Q9BQ90	KLDC3_HUMAN	Kelch domain-containing protein 3	12606021	A novel testis-specific RAG2-like protein, Peas: its expression in pachytene spermatocyte cytoplasm and meiotic chromatin.

Q9GQQ0	SPIN_DROME	Protein spinster	12408844	Unrestricted synaptic growth in spinster-a late endosomal protein implicated in TGF-beta-mediated synaptic growth regulation.

Q18221	SET2_CAEEL	Probable histone-lysine N-methyltransferase set-2	12242227	A targeted RNAi screen for genes involved in chromosome morphogenesis and nuclear organization in the Caenorhabditis elegans germline.

Q9DBZ5	EIF3K_MOUSE	Eukaryotic translation initiation factor 3 subunit K	17581632	Reconstitution reveals the functional core of mammalian eIF3.

Q04372	TAP42_YEAST	Type 2A phosphatase-associated protein 42	10329624	Tor proteins and protein phosphatase 2A reciprocally regulate Tap42 in controlling cell growth in yeast.

P43254	COP1_ARATH	E3 ubiquitin-protein ligase COP1	8205001	Genetic and molecular analysis of an allelic series of cop1 mutants suggests functional roles for the multiple protein domains.

Q06408	ARO10_YEAST	Transaminated amino acid decarboxylase	12902239	Identification and characterization of phenylpyruvate decarboxylase genes in Saccharomyces cerevisiae.

P23542	AATC_YEAST	Aspartate aminotransferase, cytoplasmic	1859361	The amino acid sequence of the aspartate aminotransferase from baker's yeast (Saccharomyces cerevisiae).

Q9QZ48	ZBT7A_RAT	Zinc finger and BTB domain-containing protein 7A	10477728	Osteoclast-derived zinc finger (OCZF) protein with POZ domain, a possible transcriptional repressor, is involved in osteoclastogenesis.

P40971	LYS14_YEAST	Lysine biosynthesis regulatory protein LYS14	7935367	Repression of the genes for lysine biosynthesis in Saccharomyces cerevisiae is caused by limitation of Lys14-dependent transcriptional activation.

P50281	MMP14_HUMAN	Matrix metalloproteinase-14	8015608	A matrix metalloproteinase expressed on the surface of invasive tumour cells.

O88807	PADI4_RAT	Protein-arginine deiminase type-4	9738944	Molecular cloning of two novel types of peptidylarginine deiminase cDNAs from retinoic acid-treated culture of a newborn rat keratinocyte cell line.

Q9EPC1	PARVA_MOUSE	Alpha-parvin	11134073	Actopaxin, a new focal adhesion protein that binds paxillin LD motifs and actin and regulates cell adhesion.

P35125	UBP6_HUMAN	Ubiquitin carboxyl-terminal hydrolase 6	15509780	The TBC (Tre-2/Bub2/Cdc16) domain protein TRE17 regulates plasma membrane-endosomal trafficking through activation of Arf6.

O55207	SYNJ2_RAT	Synaptojanin-2	11498538	Identification and characterization of a synaptojanin 2 splice isoform predominantly expressed in nerve terminals.

Q12692	H2AZ_YEAST	Histone H2A.Z	15045029	A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin.

Q13546	RIPK1_HUMAN	Receptor-interacting serine/threonine-protein kinase 1	17449468	RBCK1 negatively regulates tumor necrosis factor- and interleukin-1- triggered NF-kappaB activation by targeting TAB2/3 for degradation.

O49482	CADH5_ARATH	Cinnamyl alcohol dehydrogenase 5	15937231	CINNAMYL ALCOHOL DEHYDROGENASE-C and -D are the primary genes involved in lignin biosynthesis in the floral stem of Arabidopsis.

P05089	ARGI1_HUMAN	Arginase-1	3540966	Molecular cloning and nucleotide sequence of cDNA for human liver arginase.

Q00960	NMDE2_RAT	Glutamate [NMDA] receptor subunit epsilon-2	1350383	Heteromeric NMDA receptors: molecular and functional distinction of subtypes.

P38830	NDT80_YEAST	Meiosis-specific transcription factor NDT80	11035815	The pachytene checkpoint prevents accumulation and phosphorylation of the meiosis-specific transcription factor Ndt80.

P25963	IKBA_HUMAN	NF-kappa-B inhibitor alpha	1493333	I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding.

Q9JJA9	GRASP_MOUSE	General receptor for phosphoinositides 1-associated scaffold protein	10828067	Interaction of GRASP, a protein encoded by a novel retinoic acid- induced gene, with members of the cytohesin family of guanine nucleotide exchange factors.

P37890	CBP1_ORYSJ	Serine carboxypeptidase 1	8161571	Cloning and sequencing of the gene for type I carboxypeptidase in rice.

O74477	MCA1_SCHPO	Metacaspase-1	17898859	Overexpression of a metacaspase gene stimulates cell growth and stress response in Schizosaccharomyces pombe.

Q9VVI3	NEDD4_DROME	E3 ubiquitin-protein ligase Nedd-4	15657595	Comm function in commissural axon guidance: cell-autonomous sorting of Robo in vivo.

P40479	SDP1_YEAST	Dual-specificity protein phosphatase SDP1	12220658	YIL113w encodes a functional dual-specificity protein phosphatase which specifically interacts with and inactivates the Slt2/Mpk1p MAP kinase in S. cerevisiae.

Q9V5E1	PAL1_DROME	Peptidyl-alpha-hydroxyglycine alpha-amidating lyase 1	15198673	Drosophila uses two distinct neuropeptide amidating enzymes, dPAL1 and dPAL2.

Q9H2F5	EPC1_HUMAN	Enhancer of polycomb homolog 1	14966270	Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans.

Q06160	SPH1_YEAST	Protein SPH1	9443897	The Spa2-related protein, Sph1p, is important for polarized growth in yeast.

Q9SWI1	PKS1_ARATH	Protein PHYTOCHROME KINASE SUBSTRATE 1	16777956	PHYTOCHROME KINASE SUBSTRATE 1 is a phototropin 1 binding protein required for phototropism.

O35714	TNR18_MOUSE	Tumor necrosis factor receptor superfamily member 18	12478477	GITR interacts with the pro-apoptotic protein Siva and induces apoptosis.

Q21502	MEP1_CAEEL	MOG interacting and ectopic P-granules protein 1	12088146	The MEP-1 zinc-finger protein acts with MOG DEAH box proteins to control gene expression via the fem-3 3' untranslated region in Caenorhabditis elegans.

O60184	CYC8_SCHPO	General transcriptional corepressor ssn6	15632072	Functional comparison of the Tup11 and Tup12 transcriptional corepressors in fission yeast.

P63004	LIS1_RAT	Platelet-activating factor acetylhydrolase IB subunit alpha	11056530	Regulation of cytoplasmic dynein behaviour and microtubule organization by mammalian Lis1.

Q9VR07	INE_DROME	Sodium- and chloride-dependent GABA transporter ine	11517334	Control of Drosophila perineurial glial growth by interacting neurotransmitter-mediated signaling pathways.

O01836	GLH3_CAEEL	ATP-dependent RNA helicase glh-3	10851135	Combinatorial RNA interference indicates GLH-4 can compensate for GLH-1; these two P granule components are critical for fertility in C. elegans.

O14140	DSS1_SCHPO	mRNA export factor dss1	15990877	Homolog of BRCA2-interacting Dss1p and Uap56p link Mlo3p and Rae1p for mRNA export in fission yeast.

P0AGB6	RPOE_ECOLI	RNA polymerase sigma-E factor	7889935	The rpoE gene encoding the sigma E (sigma 24) heat shock sigma factor of Escherichia coli.

P16118	F261_HUMAN	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	2837207	Molecular cloning, sequence analysis, and expression of a human liver cDNA coding for fructose-6-P,2-kinase:fructose-2,6-bisphosphatase.

Q13257	MD2L1_HUMAN	Mitotic spindle assembly checkpoint protein MAD2A	12006501	Crystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpoint.

Q7XJ98	KATAM_ARATH	Xyloglucan galactosyltransferase KATAMARI1	15863516	KATAMARI1/MURUS3 is a novel Golgi membrane protein that is required for endomembrane organization in Arabidopsis.

O74880	MCES_SCHPO	mRNA cap guanine-N7 methyltransferase	16428435	Cyclin-dependent kinase 9 (Cdk9) of fission yeast is activated by the CDK-activating kinase Csk1, overlaps functionally with the TFIIH- associated kinase Mcs6, and associates with the mRNA cap methyltransferase Pcm1 in vivo.

P56261	CEBPE_RAT	CCAAT/enhancer-binding protein epsilon	1884998	A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro.

O95196	CSPG5_HUMAN	Chondroitin sulfate proteoglycan 5	9950058	Cloning and chromosomal mapping of the human gene of neuroglycan C (NGC), a neural transmembrane chondroitin sulfate proteoglycan with an EGF module.

Q9JLV1	BAG3_MOUSE	BAG family molecular chaperone regulator 3	10597216	Bis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell death.

Q1ZXJ0	CLCD_DICDI	Chloride channel protein D	17659086	High-throughput analysis of spatio-temporal dynamics in Dictyostelium.

Q9Y7R4	SET1_SCHPO	Histone-lysine N-methyltransferase, H3 lysine-4 specific	12488447	High conservation of the Set1/Rad6 axis of histone 3 lysine 4 methylation in budding and fission yeasts.

P78310	CXAR_HUMAN	Coxsackievirus and adenovirus receptor	9036860	Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5.

Q5G1T1	PP272_ARATH	Pentatricopeptide repeat-containing protein At3g49170, chloroplastic	15647901	Arabidopsis emb175 and other ppr knockout mutants reveal essential roles for pentatricopeptide repeat (PPR) proteins in plant embryogenesis.

Q9Y7U9	CCA2_SCHPO	Putative tRNA nucleotidyltransferase 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8IM46	YPF02_PLAF7	Uncharacterized protein PF14_0045	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

Q92990	GLMN_HUMAN	Glomulin	12604780	The FKBP-associated protein FAP48 is an antiproliferative molecule and a player in T cell activation that increases IL2 synthesis.

Q6UWY0	ARSK_HUMAN	Arylsulfatase K	16174644	Sulfatases and sulfatase modifying factors: an exclusive and promiscuous relationship.

P54622	SSBP_DROME	Single-stranded DNA-binding protein, mitochondrial	8206370	RNA- and single-stranded DNA-binding (SSB) proteins expressed during Drosophila melanogaster oogenesis: a homolog of bacterial and eukaryotic mitochondrial SSBs.

P09938	RIR2_YEAST	Ribonucleoside-diphosphate reductase small chain 1	10716984	Yeast ribonucleotide reductase has a heterodimeric iron-radical- containing subunit.

Q9UBV2	SE1L1_HUMAN	Protein sel-1 homolog 1	18264092	OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD.

Q12499	NOP58_YEAST	Nucleolar protein 58	9632712	Nop5p is a small nucleolar ribonucleoprotein component required for pre-18S rRNA processing in yeast.

Q9ET47	ESPN_MOUSE	Espin	10588661	Espin contains an additional actin-binding site in its N terminus and is a major actin-bundling protein of the Sertoli cell-spermatid ectoplasmic specialization junctional plaque.

Q94BT6	ADO1_ARATH	Adagio protein 1	10998191	LKP1 (LOV kelch protein 1): a factor involved in the regulation of flowering time in Arabidopsis.

Q9FGM1	PYL8_ARATH	Abscisic acid receptor PYL8	19889877	The nuclear interactor PYL8/RCAR3 of Fagus sylvatica FsPP2C1 is a positive regulator of abscisic acid signaling in seeds and stress.

P43155	CACP_HUMAN	Carnitine O-acetyltransferase	7829107	Molecular cloning of cDNAs encoding human carnitine acetyltransferase and mapping of the corresponding gene to chromosome 9q34.1.

Q8VCE6	NT5M_MOUSE	5'(3')-deoxyribonucleotidase, mitochondrial	12234672	Mouse cytosolic and mitochondrial deoxyribonucleotidases: cDNA cloning of the mitochondrial enzyme, gene structures, chromosomal mapping and comparison with the human orthologs.

Q6UWB1	I27RA_HUMAN	Interleukin-27 receptor subunit alpha	9600072	Cloning and characterization of a novel class I cytokine receptor.

O95158	NXPH4_HUMAN	Neurexophilin-4	9570794	Neurexophilins form a conserved family of neuropeptide-like glycoproteins.

P60766	CDC42_MOUSE	Cell division control protein 42 homolog	10490598	The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins.

O60216	RAD21_HUMAN	Double-strand-break repair protein rad21 homolog	8812457	Sequence conservation of the rad21 Schizosaccharomyces pombe DNA double-strand break repair gene in human and mouse.

Q9SJC4	NUDT6_ARATH	Nudix hydrolase 6	15878881	Comprehensive analysis of cytosolic nudix hydrolases in Arabidopsis thaliana.

Q96J01	THOC3_HUMAN	THO complex subunit 3	15998806	Recruitment of the human TREX complex to mRNA during splicing.

O80725	AB4B_ARATH	ABC transporter B family member 4	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

P39009	DUN1_YEAST	DNA damage response protein kinase DUN1	11904430	The Dun1 checkpoint kinase phosphorylates and regulates the ribonucleotide reductase inhibitor Sml1.

O15304	SIVA_HUMAN	Apoptosis regulatory protein Siva	15034012	Siva-1 and an alternative splice form lacking the death domain, Siva- 2, similarly induce apoptosis in T lymphocytes via a caspase-dependent mitochondrial pathway.

Q13216	ERCC8_HUMAN	DNA excision repair protein ERCC-8	12732143	The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage.

O74919	RNC1_SCHPO	RNA-binding protein rnc1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9P7K8	SPT4_SCHPO	Transcription elongation factor spt4	11893740	Interactions between fission yeast mRNA capping enzymes and elongation factor Spt5.

Q2M3T9	HYAL4_HUMAN	Hyaluronidase-4	10493834	Expression analysis of six paralogous human hyaluronidase genes clustered on chromosomes 3p21 and 7q31.

Q13596	SNX1_HUMAN	Sorting nexin-1	9819414	Identification of a family of sorting nexin molecules and characterization of their association with receptors.

P04646	RL35A_RAT	60S ribosomal protein L35a	3753935	Nucleotide sequence of cloned cDNA specific for rat ribosomal protein L35a.

P19956	RM44_YEAST	54S ribosomal protein L44, mitochondrial	2060626	Extended N-terminal sequencing of proteins of the large ribosomal subunit from yeast mitochondria.

Q9NWV8	MRI40_HUMAN	BRCA1-A complex subunit MERIT40	19261746	MERIT40 controls BRCA1-Rap80 complex integrity and recruitment to DNA double-strand breaks.

Q6NLV4	FY_ARATH	Flowering time control protein FY	12809608	FY is an RNA 3' end-processing factor that interacts with FCA to control the Arabidopsis floral transition.

Q24564	MERH_DROME	Moesin/ezrin/radixin homolog 2	20159598	Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded.

P30098	NK3R_CAVPO	Neuromedin-K receptor	1315051	Expression cloning of cDNA encoding a seven-helix receptor from human placenta with affinity for opioid ligands.

Q23120	RSP2_CAEEL	Probable splicing factor, arginine/serine-rich 2	10906451	Unique and redundant functions of SR proteins, a conserved family of splicing factors, in Caenorhabditis elegans development.

Q98TW1	NCOA2_DANRE	Nuclear receptor coactivator 2	17583703	An F-domain introduced by alternative splicing regulates activity of the zebrafish thyroid hormone receptor alpha.

Q9NRD1	FBX6_HUMAN	F-box only protein 6	19716789	The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress.

Q12532	YP009_YEAST	Uncharacterized protein YPL009C	14562095	Global analysis of protein localization in budding yeast.

Q8CIT9	SBSN_MOUSE	Suprabasin	12228223	Suprabasin, a novel epidermal differentiation marker and potential cornified envelope precursor.

Q9D9V2	AFAF_MOUSE	Acrosome formation-associated factor	16831425	Afaf, a novel vesicle membrane protein, is related to acrosome formation in murine testis.

Q15120	PDK3_HUMAN	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial	7499431	Diversity of the pyruvate dehydrogenase kinase gene family in humans.

Q03388	VPS72_YEAST	Vacuolar protein sorting-associated protein 72	16299513	Swc2 is a widely conserved H2AZ-binding module essential for ATP- dependent histone exchange.

Q7L1T6	NB5R4_HUMAN	Cytochrome b5 reductase 4	15131110	NCB5OR is a novel soluble NAD(P)H reductase localized in the endoplasmic reticulum.

Q9QXT5	EGFL7_MOUSE	Epidermal growth factor-like protein 7	15162510	Egfl7, a novel epidermal growth factor-domain gene expressed in endothelial cells.

P28659	CELF1_MOUSE	CUGBP Elav-like family member 1	15830352	Dynamic balance between activation and repression regulates pre-mRNA alternative splicing during heart development.

P84092	AP2M1_RAT	AP-2 complex subunit mu	3148444	Molecular cloning and complete amino acid sequence of AP50, an assembly protein associated with clathrin-coated vesicles.

P13099	TOP3_YEAST	DNA topoisomerase 3	15899853	Yeast Rmi1/Nce4 controls genome stability as a subunit of the Sgs1- Top3 complex.

P36167	SRL3_YEAST	Protein SRL3	11914276	Subcellular localization of the yeast proteome.

P22449	HNF4A_RAT	Hepatocyte nuclear factor 4-alpha	2279702	Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily.

Q9UUA4	SEC66_SCHPO	Translocation protein sec66	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O13663	GPI13_SCHPO	GPI ethanolamine phosphate transferase 3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O74457	YCGC_SCHPO	Uncharacterized N-acetyltransferase C16C4.12	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8IUX7	AEBP1_HUMAN	Adipocyte enhancer-binding protein 1	9624159	Aortic carboxypeptidase-like protein, a novel protein with discoidin and carboxypeptidase-like domains, is up-regulated during vascular smooth muscle cell differentiation.

Q99250	SCN2A_HUMAN	Sodium channel protein type 2 subunit alpha	1325650	Primary structure, chromosomal localization, and functional expression of a voltage-gated sodium channel from human brain.

O74630	ATM_SCHPO	Serine/threonine-protein kinase tel1	12196391	Telomere binding of checkpoint sensor and DNA repair proteins contributes to maintenance of functional fission yeast telomeres.

O04017	NAC98_ARATH	Protein CUP-SHAPED COTYLEDON 2	17098808	The balance between the MIR164A and CUC2 genes controls leaf margin serration in Arabidopsis.

P54756	EPHA5_HUMAN	Ephrin type-A receptor 5	7898931	cDNA cloning and tissue distribution of five human EPH-like receptor protein-tyrosine kinases.

O43760	SNG2_HUMAN	Synaptogyrin-2	9760194	Characterization of the human synaptogyrin gene family.

P40879	S26A3_HUMAN	Chloride anion exchanger	7683425	Identification of a colon mucosa gene that is down-regulated in colon adenomas and adenocarcinomas.

Q9BXS6	NUSAP_HUMAN	Nucleolar and spindle-associated protein 1	12963707	NuSAP, a novel microtubule-associated protein involved in mitotic spindle organization.

P53290	GTR2_YEAST	GTP-binding protein GTR2	15989961	The TOR and EGO protein complexes orchestrate microautophagy in yeast.

Q86CR9	ATG7_DICDI	Ubiquitin-like modifier-activating enzyme atg7	12626495	Macroautophagy is required for multicellular development of the social amoeba Dictyostelium discoideum.

Q09882	PRP45_SCHPO	Pre-mRNA-processing protein 45	11414703	The fission yeast ortholog of the coregulator SKIP interacts with the small subunit of U2AF.

Q9UIS9	MBD1_HUMAN	Methyl-CpG-binding domain protein 1	10454587	Methylation-mediated transcriptional silencing in euchromatin by methyl-CpG binding protein MBD1 isoforms.

P21926	CD9_HUMAN	CD9 antigen	8478605	Suppression of cell motility and metastasis by transfection with human motility-related protein (MRP-1/CD9) DNA.

P29083	T2EA_HUMAN	General transcription factor IIE subunit 1	7667268	Evolutionary conservation of human TATA-binding-polypeptide- associated factors TAFII31 and TAFII80 and interactions of TAFII80 with other TAFs and with general transcription factors.

P06881	CALCA_HUMAN	Calcitonin gene-related peptide 1	1318039	Isolation and characterization of peptides which act on rat platelets, from a pheochromocytoma.

O14044	PNO1_SCHPO	Pre-rRNA-processing protein pno1	15116432	Identification of genes encoding putative nucleoporins and transport factors in the fission yeast Schizosaccharomyces pombe: a deletion analysis.

P07866	LTE1_YEAST	Guanine nucleotide exchange factor LTE1	17121813	A role for Lte1p (a low temperature essential protein involved in mitosis) in proprotein processing in the yeast secretory pathway.

P0ADV9	LPTC_ECOLI	Lipopolysaccharide export system protein lptC	18424520	Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.

O94395	KU70_SCHPO	ATP-dependent DNA helicase II subunit 1	11029034	Protection of telomeres by the Ku protein in fission yeast.

P35410	MAS1L_HUMAN	Mas-related G-protein coupled receptor MRG	1723144	Cloning and functional characterization of a novel mas-related gene, modulating intracellular angiotensin II actions.

P39966	PP2C2_YEAST	Protein phosphatase 2C homolog 2	10580002	Dephosphorylation of cyclin-dependent kinases by type 2C protein phosphatases.

Q2Z1R2	SOX1B_DANRE	Transcription factor Sox-1b	16408288	Comparative genomic and expression analysis of group B1 sox genes in zebrafish indicates their diversification during vertebrate evolution.

Q9UER7	DAXX_HUMAN	Death domain-associated protein 6	9215629	Daxx, a novel Fas-binding protein that activates JNK and apoptosis.

P08144	AMYA_DROME	Alpha-amylase A	11156987	Molecular evolution of duplicated amylase gene regions in Drosophila melanogaster: evidence of positive selection in the coding regions and selective constraints in the cis-regulatory regions.

Q96Q15	SMG1_HUMAN	Serine/threonine-protein kinase SMG1	15175154	The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells.

P11362	FGFR1_HUMAN	Basic fibroblast growth factor receptor 1	2159626	Complete sequence of a human receptor for acidic and basic fibroblast growth factors.

P26883	FKB1A_MOUSE	Peptidyl-prolyl cis-trans isomerase FKBP1A	1722474	cDNA encoding murine FK506-binding protein (FKBP): nucleotide and deduced amino acid sequence.

Q9Y0T2	FBXA_DICDI	F-box/WD repeat-containing protein A	10898960	An F-Box/WD40 repeat-containing protein important for Dictyostelium cell-type proportioning, slug behaviour, and culmination.

Q3UPW2	ELF3_MOUSE	ETS-related transcription factor Elf-3	11893733	Activation of the murine type II transforming growth factor-beta receptor gene: up-regulation and function of the transcription factor Elf-3/Ert/Esx/Ese-1.

Q01477	UBP3_YEAST	Ubiquitin carboxyl-terminal hydrolase 3	1429680	Ubiquitin-specific proteases of Saccharomyces cerevisiae. Cloning of UBP2 and UBP3, and functional analysis of the UBP gene family.

P33532	BSU1_SCHPO	Vitamin B6 transporter bsu1	15701794	Amiloride uptake and toxicity in fission yeast are caused by the pyridoxine transporter encoded by bsu1+ (car1+).

P47013	DS1P1_YEAST	Dihydrosphingosine 1-phosphate phosphatase LCB3	11278643	Calcium influx and signaling in yeast stimulated by intracellular sphingosine 1-phosphate accumulation.

Q9Y6N9	USH1C_HUMAN	Harmonin	10973247	A defect in harmonin, a PDZ domain-containing protein expressed in the inner ear sensory hair cells, underlies Usher syndrome type 1C.

O96759	ADAS_DICDI	Alkyldihydroxyacetonephosphate synthase	17562315	The crucial step in ether phospholipid biosynthesis: structural basis of a noncanonical reaction associated with a peroxisomal disorder.

Q9NZL9	MAT2B_HUMAN	Methionine adenosyltransferase 2 subunit beta	10644686	Cloning, expression, and functional characterization of the beta regulatory subunit of human methionine adenosyltransferase (MAT II).

Q62137	JAK3_MOUSE	Tyrosine-protein kinase JAK3	8022486	Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells.

O46036	CTBP_DROME	C-terminal-binding protein	9524128	Drosophila CtBP: a Hairy-interacting protein required for embryonic segmentation and hairy-mediated transcriptional repression.

Q2M3M2	SC5A9_HUMAN	Sodium/glucose cotransporter 4	15607332	SLC5A9/SGLT4, a new Na+-dependent glucose transporter, is an essential transporter for mannose, 1,5-anhydro-D-glucitol, and fructose.

P06838	RAD10_YEAST	DNA repair protein RAD10	8621533	Nucleotide excision repair in yeast is mediated by sequential assembly of repair factors and not by a pre-assembled repairosome.

Q8IEF6	MYB1_PLAF7	Myb1 protein	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

Q69AB1	TXND8_RAT	Thioredoxin domain-containing protein 8	15181017	Spermatocyte/spermatid-specific thioredoxin-3, a novel Golgi apparatus-associated thioredoxin, is a specific marker of aberrant spermatogenesis.

Q9Z250	LIN7A_RAT	Protein lin-7 homolog A	15024025	Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins.

P51142	DVL2_XENLA	Segment polarity protein dishevelled homolog DVL-2	18552847	Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells.

P07170	KAD1_YEAST	Adenylate kinase 1	2848829	Analysis and in vivo disruption of the gene coding for adenylate kinase (ADK1) in the yeast Saccharomyces cerevisiae.

Q9HAU4	SMUF2_HUMAN	E3 ubiquitin-protein ligase SMURF2	11158580	Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase.

P51164	ATP4B_HUMAN	Potassium-transporting ATPase subunit beta	1656976	cDNA cloning of the beta-subunit of the human gastric H,K-ATPase.

O94504	TRX2_SCHPO	Thioredoxin-2, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q3U6B2	GP183_MOUSE	G-protein coupled receptor 183	19597478	EBI2 mediates B cell segregation between the outer and centre follicle.

P49739	MCM3M_XENLA	Maternal DNA replication licensing factor mcm3	9214647	Licensing of DNA replication by a multi-protein complex of MCM/P1 proteins in Xenopus eggs.

Q10243	VPS26_SCHPO	Vacuolar protein sorting-associated protein 26	16622069	Vacuolar protein sorting receptor in Schizosaccharomyces pombe.

Q67E05	BPI_MOUSE	Bactericidal permeability-increasing protein	15590754	A murine antibacterial ortholog to human bactericidal/permeability- increasing protein (BPI) is expressed in testis, epididymis, and bone marrow.

Q9EPX4	P2Y12_RAT	P2Y purinoceptor 12	11196645	Identification of the platelet ADP receptor targeted by antithrombotic drugs.

Q09147	FGFR2_DROME	Fibroblast growth factor receptor homolog 2	1325393	Breathless, a Drosophila FGF receptor homolog, is essential for migration of tracheal and specific midline glial cells.

P00334	ADH_DROME	Alcohol dehydrogenase	8461298	Site-specific mutagenesis of Drosophila alcohol dehydrogenase: evidence for involvement of tyrosine-152 and lysine-156 in catalysis.

Q8SWV6	FICD_DROME	Adenosine monophosphate-protein transferase FICD homolog	19503829	Fido, a novel AMPylation domain common to fic, doc, and AvrB.

O15178	BRAC_HUMAN	Brachyury protein	8963900	The human homolog T of the mouse T(Brachyury) gene; gene structure, cDNA sequence, and assignment to chromosome 6q27.

P27815	PDE4A_HUMAN	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	9677330	Identification and characterization of the human homologue of the short PDE4A cAMP-specific phosphodiesterase 4A variant RD1 (PDE4A1) by analysis of the human HSPDE4A gene locus located at chromosome 19p13.2.

Q08462	ADCY2_HUMAN	Adenylate cyclase type 2	1427768	Different chromosomal localization of two adenylyl cyclase genes expressed in human brain.

Q9ERH8	S28A3_MOUSE	Solute carrier family 28 member 3	11032837	Molecular identification and characterization of novel human and mouse concentrative Na+-nucleoside cotransporter proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib).

Q5VZF2	MBNL2_HUMAN	Muscleblind-like protein 2	16946708	Interaction of muscleblind, CUG-BP1 and hnRNP H proteins in DM1- associated aberrant IR splicing.

P55327	TPD52_HUMAN	Tumor protein D52	9484778	Identification of homo- and heteromeric interactions between members of the breast carcinoma-associated D52 protein family using the yeast two-hybrid system.

O14295	PLR1_SCHPO	Pyridoxal reductase	10438489	Purification, molecular cloning, and catalytic activity of Schizosaccharomyces pombe pyridoxal reductase. A possible additional family in the aldo-keto reductase superfamily.

P18848	ATF4_HUMAN	Cyclic AMP-dependent transcription factor ATF-4	16682973	The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4.

O54772	SMRD2_RAT	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2	9427560	Gene structure of rat BAF60b, a component of mammalian SWI/SNF complexes, and its physical linkage to the growth hormone gene and transcription factor SUG/proteasome p45 gene.

Q24563	DOPR2_DROME	Dopamine receptor 2	8663989	DAMB, a novel dopamine receptor expressed specifically in Drosophila mushroom bodies.

P38439	LEO1_YEAST	RNA polymerase-associated protein LEO1	15643076	Separation of the Saccharomyces cerevisiae Paf1 complex from RNA polymerase II results in changes in its subnuclear localization.

P0A776	RPPH_ECOLI	RNA pyrophosphohydrolase	18202662	The bacterial enzyme RppH triggers messenger RNA degradation by 5' pyrophosphate removal.

P14618	KPYM_HUMAN	Pyruvate kinase isozymes M1/M2	2854097	Human M2-type pyruvate kinase: cDNA cloning, chromosomal assignment and expression in hepatoma.

Q6P902	TXND2_MOUSE	Thioredoxin domain-containing protein 2	12149401	Cloning, expression and characterization of mouse spermatid specific thioredoxin-1 gene and protein.

Q64686	SIA7C_RAT	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3	8631773	Molecular cloning of a developmentally regulated N- acetylgalactosamine alpha2,6-sialyltransferase specific for sialylated glycoconjugates.

P39015	STM1_YEAST	Suppressor protein STM1	12207228	STM1, a gene which encodes a guanine quadruplex binding protein, interacts with CDC13 in Saccharomyces cerevisiae.

Q9VYX7	PGPSA_DROME	Peptidoglycan-recognition protein SA	11106397	A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster.

O80501	RBH1B_ARATH	Ras-related protein RABH1B	18182439	Localization and domain characterization of Arabidopsis golgin candidates.

P70512	HNF6_RAT	Hepatocyte nuclear factor 6	8790352	Hepatocyte nuclear factor 6, a transcription factor that contains a novel type of homeodomain and a single cut domain.

Q12379	SWM1_YEAST	Anaphase-promoting complex subunit SWM1	12609981	Mnd2 and Swm1 are core subunits of the Saccharomyces cerevisiae anaphase-promoting complex.

O43513	MED7_HUMAN	Mediator of RNA polymerase II transcription subunit 7	9989412	The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1.

O43511	S26A4_HUMAN	Pendrin	10192399	The Pendred syndrome gene encodes a chloride-iodide transport protein.

P53691	PPID_YEAST	Peptidyl-prolyl cis-trans isomerase CPR6	8873448	Identification of two CyP-40-like cyclophilins in Saccharomyces cerevisiae, one of which is required for normal growth.

Q8IY84	NIM1_HUMAN	Serine/threonine-protein kinase NIM1	15733851	Identification of the sucrose non-fermenting related kinase SNRK, as a novel LKB1 substrate.

P58019	CD59B_MOUSE	CD59B glycoprotein	10946279	Identification and functional characterization of a new gene encoding the mouse terminal complement inhibitor CD59.

Q9CQN4	SOSD1_MOUSE	Sclerostin domain-containing protein 1	14623234	Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot.

Q9XHP1	2SS1_SESIN	2S seed storage protein 1	10606554	Molecular cloning of 11S globulin and 2S albumin, the two major seed storage proteins in sesame.

P24278	ZBT25_HUMAN	Zinc finger and BTB domain-containing protein 25	2027750	The KUP gene, located on human chromosome 14, encodes a protein with two distant zinc fingers.

O42342	SOX7_XENLA	Transcription factor Sox-7	15680368	SOX7 is an immediate-early target of VegT and regulates Nodal-related gene expression in Xenopus.

P38710	INM1_YEAST	Inositol monophosphatase 1	14562095	Global analysis of protein localization in budding yeast.

P38815	YPT35_YEAST	PX domain-containing protein YPT35	15263065	The phox homology (PX) domain protein interaction network in yeast.

P35154	SCPA_BACSU	Segregation and condensation protein A	12100548	Discovery of two novel families of proteins that are proposed to interact with prokaryotic SMC proteins, and characterization of the Bacillus subtilis family members ScpA and ScpB.

P28239	IPYR2_YEAST	Inorganic pyrophosphatase, mitochondrial	1648084	Yeast PPA2 gene encodes a mitochondrial inorganic pyrophosphatase that is essential for mitochondrial function.

P55083	MFAP4_HUMAN	Microfibril-associated glycoprotein 4	7633408	The gene for a human microfibril-associated glycoprotein is commonly deleted in Smith-Magenis syndrome patients.

P15502	ELN_HUMAN	Elastin	9873040	Cutis laxa arising from frameshift mutations in exon 30 of the elastin gene (ELN).

P10275	ANDR_HUMAN	Androgen receptor	19345326	Regulation of androgen receptor transcriptional activity and specificity by RNF6-induced ubiquitination.

O60759	CYTIP_HUMAN	Cytohesin-interacting protein	12606567	Attenuation of cell adhesion in lymphocytes is regulated by CYTIP, a protein which mediates signal complex sequestration.

O42261	IRX3_XENLA	Iroquois-class homeodomain protein irx-3	18715948	A dual requirement for Iroquois genes during Xenopus kidney development.

B2RTY4	MYO9A_HUMAN	Myosin-IXa	10409426	The cloning and developmental expression of unconventional myosin IXA (MYO9A) a gene in the Bardet-Biedl syndrome (BBS4) region at chromosome 15q22-q23.

Q9U1N0	HRP65_CHITE	Hrp65 protein	10648560	Electron tomography reveals posttranscriptional binding of pre-mRNPs to specific fibers in the nucleoplasm.

P24784	DBP1_YEAST	ATP-dependent RNA helicase DBP1	14763975	Dynamics and processivity of 40S ribosome scanning on mRNA in yeast.

P32325	DBF4_YEAST	Protein DBF4	8474449	Cell cycle regulation of the yeast Cdc7 protein kinase by association with the Dbf4 protein.

Q9USX0	PVG3_SCHPO	Beta-1,3-galactosyltransferase pvg3	15173185	Five genes involved in biosynthesis of the pyruvylated Galbeta1,3- epitope in Schizosaccharomyces pombe N-linked glycans.

P53083	MDM34_YEAST	Mitochondrial distribution and morphology protein 34	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

P38325	OM14_YEAST	Mitochondrial outer membrane protein OM14	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

P58012	FOXL2_HUMAN	Forkhead box protein L2	12630957	Sporadic and familial blepharophimosis -ptosis-epicanthus inversus syndrome: FOXL2 mutation screen and MRI study of the superior levator eyelid muscle.

O13874	YE19_SCHPO	Uncharacterized NOC2 family protein C1B3.09c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O22161	ADLO1_ARATH	Protein ARABIDILLO 1	16434475	Armadillo-related proteins promote lateral root development in Arabidopsis.

O74562	SEC8_SCHPO	Exocyst complex component sec8	11854409	The multiprotein exocyst complex is essential for cell separation in Schizosaccharomyces pombe.

Q69ZM6	STK36_MOUSE	Serine/threonine-protein kinase 36	16055717	Loss of the serine/threonine kinase fused results in postnatal growth defects and lethality due to progressive hydrocephalus.

O59762	GNR1_SCHPO	Guanine nucleotide-binding protein negative regulator 1	16884933	Identification of Gnr1p, a negative regulator of G alpha signalling in Schizosaccharomyces pombe, and its complementation by human G beta subunits.

Q9NPH6	OBP2B_HUMAN	Odorant-binding protein 2b	10607840	A novel human odorant-binding protein gene family resulting from genomic duplicons at 9q34: differential expression in the oral and genital spheres.

Q9ZNV8	AHP2_ARATH	Histidine-containing phosphotransfer protein 2	10050311	Histidine-containing phosphotransfer (HPt) signal transducers implicated in His-to-Asp phosphorelay in Arabidopsis.

P36415	HS7C1_DICDI	Heat shock cognate 70 kDa protein 1	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q99418	CYH2_HUMAN	Cytohesin-2	9417041	ARNO is a guanine nucleotide exchange factor for ADP-ribosylation factor 6.

O35084	CP27B_MOUSE	25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	9295274	25-hydroxyvitamin D3 1alpha-hydroxylase and vitamin D synthesis.

Q9D7C9	NRK2_MOUSE	Nicotinamide riboside kinase 2	10613898	A novel muscle-specific beta 1 integrin binding protein (MIBP) that modulates myogenic differentiation.

Q9FZ89	Y1815_ARATH	UPF0426 protein At1g28150, chloroplastic	16461379	Protein profiling of plastoglobules in chloroplasts and chromoplasts. A surprising site for differential accumulation of metabolic enzymes.

P56100	YBGT_ECOLI	Uncharacterized protein ybgT	19121005	Small membrane proteins found by comparative genomics and ribosome binding site models.

Q8K4K2	TRIB3_MOUSE	Tribbles homolog 3	12791994	TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver.

Q8X225	DIM5_NEUCR	Histone-lysine N-methyltransferase, H3 lysine-9 specific dim-5	12887903	Structural basis for the product specificity of histone lysine methyltransferases.

P54681	RTOA_DICDI	Protein rtoA	12771188	A STAT-regulated, stress-induced signalling pathway in Dictyostelium.

Q9V3R1	A36DE_DROME	Accessory gland protein Acp36DE	9474779	New genes for male accessory gland proteins in Drosophila melanogaster.

P32339	HMX1_YEAST	Heme-binding protein HMX1	12699699	Cloning and expression of a heme binding protein from the genome of Saccharomyces cerevisiae.

O76365	CTU1_CAEEL	Cytoplasmic tRNA 2-thiolation protein 1	19145231	Ubiquitin-related modifier Urm1 acts as a sulphur carrier in thiolation of eukaryotic transfer RNA.

P21560	CBP3_YEAST	Protein CBP3, mitochondrial	11522252	Identification of functional regions of Cbp3p, an enzyme-specific chaperone required for the assembly of ubiquinol-cytochrome c reductase in yeast mitochondria.

O94612	YFO5_SCHPO	Uncharacterized cyclin-L1-like protein C1296.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q2TAD5	APJB_XENLA	Apelin receptor B	17412318	Paracrine and autocrine mechanisms of apelin signaling govern embryonic and tumor angiogenesis.

P53632	PAP2_YEAST	Poly(A) RNA polymerase protein 2	16431988	Nuclear RNA surveillance in Saccharomyces cerevisiae: Trf4p-dependent polyadenylation of nascent hypomethylated tRNA and an aberrant form of 5S rRNA.

Q9UBU9	NXF1_HUMAN	Nuclear RNA export factor 1	19836239	UIF, a new mRNA export adaptor that works together with REF/ALY, requires FACT for recruitment to mRNA.

O42606	NGN1_DANRE	Neurogenin-1	15659486	Wnt1 regulates neurogenesis and mediates lateral inhibition of boundary cell specification in the zebrafish hindbrain.

Q61592	GAS6_MOUSE	Growth arrest-specific protein 6	8336730	The protein encoded by a growth arrest-specific gene (gas6) is a new member of the vitamin K-dependent proteins related to protein S, a negative coregulator in the blood coagulation cascade.

Q01649	CIK1_YEAST	Spindle pole body-associated protein CIK1	10087265	Differential regulation of the Kar3p kinesin-related protein by two associated proteins, Cik1p and Vik1p.

P07356	ANXA2_MOUSE	Annexin A2	14506282	Dysferlin interacts with annexins A1 and A2 and mediates sarcolemmal wound-healing.

Q9Y6B2	EID1_HUMAN	EP300-interacting inhibitor of differentiation 1	15837424	Selective ablation of retinoblastoma protein function by the RET finger protein.

O74779	MU164_SCHPO	Microtubule-associated protein mug164	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

Q06266	TOS4_YEAST	Protein TOS4	15282802	Localization of proteins that are coordinately expressed with Cln2 during the cell cycle.

O23320	CML8_ARATH	Calmodulin-like protein 8	11855649	Characterization of three new members of the Arabidopsis thaliana calmodulin gene family: conserved and highly diverged members of the gene family functionally complement a yeast calmodulin null.

O94606	JMJ4_SCHPO	JmjC domain-containing protein 4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8CJH6	NPAS4_RAT	Neuronal PAS domain-containing protein 4	14701734	Identification of a novel basic helix-loop-helix-PAS factor, NXF, reveals a Sim2 competitive, positive regulatory role in dendritic- cytoskeleton modulator drebrin gene expression.

P14900	MURD_ECOLI	UDP-N-acetylmuramoylalanine--D-glutamate ligase	1765076	Over-production, purification and properties of the uridine diphosphate N-acetylmuramoyl-L-alanine:D-glutamate ligase from Escherichia coli.

D2XNR1	FLOT4_MEDTR	Flotillin-like protein 4	20018678	Plant flotillins are required for infection by nitrogen-fixing bacteria.

Q09161	NCBP1_HUMAN	Nuclear cap-binding protein subunit 1	11551508	Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20.

P01344	IGF2_HUMAN	Insulin-like growth factor II	6382022	Insulin-like growth factor II precursor gene organization in relation to insulin gene family.

Q96LA8	ANM6_HUMAN	Protein arginine N-methyltransferase 6	11724789	The novel human protein arginine N-methyltransferase PRMT6 is a nuclear enzyme displaying unique substrate specificity.

Q9NP86	CABP5_HUMAN	Calcium-binding protein 5	10625670	Five members of a novel Ca(2+)-binding protein (CABP) subfamily with similarity to calmodulin.

Q86YT9	JAML1_HUMAN	Junctional adhesion molecule-like	15800062	Neutrophil migration across tight junctions is mediated by adhesive interactions between epithelial CAR and a JAM-like protein on neutrophils.

Q10331	NU107_SCHPO	Nucleoporin nup107	15226438	The fission yeast Nup107-120 complex functionally interacts with the small GTPase Ran/Spi1 and is required for mRNA export, nuclear pore distribution, and proper cell division.

Q9UPQ4	TRI35_HUMAN	Tripartite motif-containing protein 35	14662771	HLS5, a novel RBCC (ring finger, B box, coiled-coil) family member isolated from a hemopoietic lineage switch, is a candidate tumor suppressor.

Q16658	FSCN1_HUMAN	Fascin	8647875	Phosphorylation of human fascin inhibits its actin binding and bundling activities.

Q3E823	COA2_YEAST	Cytochrome oxidase assembly protein 2	18541668	Coa2 is an assembly factor for yeast cytochrome C oxidase biogenesis that facilitates the maturation of cox1.

O95427	PIGN_HUMAN	GPI ethanolamine phosphate transferase 1	10069808	MCD4 encodes a conserved endoplasmic reticulum membrane protein essential for glycosylphosphatidylinositol anchor synthesis in yeast.

P50295	ARY2_MOUSE	Arylamine N-acetyltransferase 2	7545952	Arylamine N-acetyltransferase in Balb/c mice: identification of a novel mouse isoenzyme by cloning and expression in vitro.

Q870J1	STE11_PNECA	HMG-box protein STE11	12909353	Pneumocystis carinii STE11, an HMG-box protein, is phosphorylated by the mitogen activated protein kinase PCM.

Q10666	POP1_CAEEL	Protein pop-1	11807036	POP-1 controls axis formation during early gonadogenesis in C. elegans.

Q54D84	TRIA_DICDI	Trishanku	19878291	The trishanku gene and terminal morphogenesis in Dictyostelium discoideum.

P23284	PPIB_HUMAN	Peptidyl-prolyl cis-trans isomerase B	2000394	Human cyclophilin B: a second cyclophilin gene encodes a peptidyl- prolyl isomerase with a signal sequence.

Q9VHA0	SCM_DROME	Polycomb protein Scm	12771214	The Drosophila Corto protein interacts with Polycomb-group proteins and the GAGA factor.

Q12447	PAA1_YEAST	Polyamine N-acetyltransferase 1	14562095	Global analysis of protein localization in budding yeast.

Q9BZL1	UBL5_HUMAN	Ubiquitin-like protein 5	11161819	Isolation of a ubiquitin-like (UBL5) gene from a screen identifying highly expressed and conserved iris genes.

P53040	TAF6_YEAST	Transcription initiation factor TFIID subunit 6	12138208	Molecular characterization of Saccharomyces cerevisiae TFIID.

O70326	GREM1_MOUSE	Gremlin-1	15201225	Gremlin-mediated BMP antagonism induces the epithelial-mesenchymal feedback signaling controlling metanephric kidney and limb organogenesis.

O54784	DAPK3_MOUSE	Death-associated protein kinase 3	12917339	ZIP kinase triggers apoptosis from nuclear PML oncogenic domains.

P00519	ABL1_HUMAN	Tyrosine-protein kinase ABL1	15696159	JNK phosphorylation of 14-3-3 proteins regulates nuclear targeting of c-Abl in the apoptotic response to DNA damage.

O43396	TXNL1_HUMAN	Thioredoxin-like protein 1	9668102	Purification, molecular cloning, and characterization of TRP32, a novel thioredoxin-related mammalian protein of 32 kDa.

P51601	GCH1_YEAST	GTP cyclohydrolase 1	8573145	Disruption of the GTP-cyclohydrolase I gene in Saccharomyces cerevisiae.

Q8BM15	CF015_MOUSE	Uncharacterized protein C6orf15 homolog	18757743	Transcriptome-based systematic identification of extracellular matrix proteins.

P01083	IAA2_WHEAT	Alpha-amylase inhibitor 0.28	1932677	Site-directed mutagenesis and expression in Escherichia coli of WMAI- 1, a wheat monomeric inhibitor of insect alpha-amylase.

P42223	SBE2_YEAST	Protein SBE2	10679005	Sbe2p and sbe22p, two homologous Golgi proteins involved in yeast cell wall formation.

Q63151	ACSL3_RAT	Long-chain-fatty-acid--CoA ligase 3	8663269	Molecular characterization and expression of rat acyl-CoA synthetase 3.

Q8JZQ9	EIF3B_MOUSE	Eukaryotic translation initiation factor 3 subunit B	17581632	Reconstitution reveals the functional core of mammalian eIF3.

P42224	STAT1_HUMAN	Signal transducer and activator of transcription 1-alpha/beta	9630226	Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA.

Q95RV2	CAV_DROME	Telomere-binding protein cav	12510197	The Drosophila HOAP protein is required for telomere capping.

O81283	TC159_ARATH	Translocase of chloroplast 159, chloroplastic	15028209	The Arabidopsis thaliana chloroplast proteome reveals pathway abundance and novel protein functions.

P26281	HPPK_ECOLI	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	1325970	Cloning, sequence analysis, and overexpression of Escherichia coli folK, the gene coding for 7,8-dihydro-6-hydroxymethylpterin- pyrophosphokinase.

P82094	TMF1_HUMAN	TATA element modulatory factor	10428808	Isolation and characterization of ARA160 as the first androgen receptor N-terminal-associated coactivator in human prostate cells.

Q9XZJ3	CUL2_DICDI	Cullin-2	12455979	CulB, a putative ubiquitin ligase subunit, regulates prestalk cell differentiation and morphogenesis in Dictyostelium spp.

P28042	SSBP_RAT	Single-stranded DNA-binding protein, mitochondrial	8482537	Cloning of human and rat cDNAs encoding the mitochondrial single- stranded DNA-binding protein (SSB).

P62318	SMD3_HUMAN	Small nuclear ribonucleoprotein Sm D3	11574479	Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein.

Q06321	ATG26_YEAST	Sterol 3-beta-glucosyltransferase	10224056	Cloning and functional expression of UGT genes encoding sterol glucosyltransferases from Saccharomyces cerevisiae, Candida albicans, Pichia pastoris, and Dictyostelium discoideum.

O94284	HMT2_SCHPO	Sulfide:quinone oxidoreductase, mitochondrial	10224084	A fission yeast gene for mitochondrial sulfide oxidation.

Q9NPB6	PAR6A_HUMAN	Partitioning defective 6 homolog alpha	9482110	The C-terminus of the HTLV-1 Tax oncoprotein mediates interaction with the PDZ domain of cellular proteins.

P58281	OPA1_MOUSE	Dynamin-like 120 kDa protein, mitochondrial	11847212	Primary structure of a dynamin-related mouse mitochondrial GTPase and its distribution in brain, subcellular localization, and effect on mitochondrial morphology.

O75712	CXB3_HUMAN	Gap junction beta-3 protein	9704026	Human gap junction protein connexin31: molecular cloning and expression analysis.

Q9UI30	TR112_HUMAN	tRNA methyltransferase 112 homolog	20308323	Human AlkB homolog ABH8 is a tRNA methyltransferase required for wobble uridine modification and DNA damage survival.

P50573	GBRR3_RAT	Gamma-aminobutyric acid receptor subunit rho-3	12431995	ZIP3, a new splice variant of the PKC-zeta-interacting protein family, binds to GABAC receptors, PKC-zeta, and Kv beta 2.

C0H4K2	PF08_PLAF7	Uncharacterized protein MAL7P1.13	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

P25588	MRC1_YEAST	Mediator of replication checkpoint protein 1	11715016	Mrc1 transduces signals of DNA replication stress to activate Rad53.

Q9W123	POF_DROME	Protein painting of fourth	11353870	Painting of fourth, a chromosome-specific protein in Drosophila.

P51575	P2RX1_HUMAN	P2X purinoceptor 1	9565569	P2X1 purinoceptor in human platelets. Molecular cloning and functional characterization after heterologous expression.

Q92914	FGF11_HUMAN	Fibroblast growth factor 11	8790420	Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development.

P48736	PK3CG_HUMAN	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	7624799	Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase.

P43033	LIS1_BOVIN	Platelet-activating factor acetylhydrolase IB subunit alpha	10940388	Direct association of LIS1, the lissencephaly gene product, with a mammalian homologue of a fungal nuclear distribution protein, rNUDE.

P83252	BGAL_HORVU	Beta-galactosidase	11838543	Barley beta-galactosidase: structure, function, heterogeneity, and gene origin.

Q949P1	ABAH1_ARATH	Abscisic acid 8'-hydroxylase 1	15064374	Arabidopsis CYP707As encode (+)-abscisic acid 8'-hydroxylase, a key enzyme in the oxidative catabolism of abscisic acid.

Q9Y5Y6	ST14_HUMAN	Suppressor of tumorigenicity 14 protein	10373424	Molecular cloning of cDNA for matriptase, a matrix-degrading serine protease with trypsin-like activity.

Q63639	AL1A2_RAT	Retinal dehydrogenase 2	8663198	Cloning of a cDNA encoding an aldehyde dehydrogenase and its expression in Escherichia coli. Recognition of retinal as substrate.

P60605	UB2G2_MOUSE	Ubiquitin-conjugating enzyme E2 G2	11278356	Endoplasmic reticulum (ER)-associated degradation of T cell receptor subunits. Involvement of ER-associated ubiquitin-conjugating enzymes (E2s).

Q07812	BAX_HUMAN	Apoptosis regulator BAX	9920818	Identification and characterization of baxepsilon, a novel bax variant missing the BH2 and the transmembrane domains.

P68398	TADA_ECOLI	tRNA-specific adenosine deaminase	12110595	tadA, an essential tRNA-specific adenosine deaminase from Escherichia coli.

Q9BX63	FANCJ_HUMAN	Fanconi anemia group J protein	14576433	The BRCT domain is a phospho-protein binding domain.

P18409	MDM10_YEAST	Mitochondrial distribution and morphology protein 10	15239954	The mitochondrial morphology protein Mdm10 functions in assembly of the preprotein translocase of the outer membrane.

O04719	P2C77_ARATH	Protein phosphatase 2C 77	15599761	The ABI2-dependent abscisic acid signalling controls HrpN-induced drought tolerance in Arabidopsis.

P18090	ADRB1_RAT	Beta-1 adrenergic receptor	16316992	Proteomic analysis of beta1-adrenergic receptor interactions with PDZ scaffold proteins.

P62945	RL41_HUMAN	60S ribosomal protein L41	1326959	Characterization by cDNA cloning of the mRNA of a highly basic human protein homologous to the yeast ribosomal protein YL41.

P40977	PLC1_SCHPO	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase 1	7732727	Molecular cloning of the plc1+ gene of Schizosaccharomyces pombe, which encodes a putative phosphoinositide-specific phospholipase C.

Q02204	RM13_YEAST	54S ribosomal protein L13, mitochondrial	2060626	Extended N-terminal sequencing of proteins of the large ribosomal subunit from yeast mitochondria.

Q9UK73	FEM1B_HUMAN	Protein fem-1 homolog B	10623617	Sequence, organization, and expression of the human FEM1B gene.

O35052	CDS1_RAT	Phosphatidate cytidylyltransferase 1	9345289	Extraction and stabilization of mammalian CDP-diacylglycerol synthase activity.

A1IGX5	FIBIN_DANRE	Fin bud initiation factor	17196583	Fibin, a novel secreted lateral plate mesoderm signal, is essential for pectoral fin bud initiation in zebrafish.

P38166	SFT2_YEAST	Protein transport protein SFT2	10406798	Got1p and Sft2p: membrane proteins involved in traffic to the Golgi complex.

P51809	VAMP7_HUMAN	Vesicle-associated membrane protein 7	10888671	Syntaxin 7 and VAMP-7 are soluble N-ethylmaleimide-sensitive factor attachment protein receptors required for late endosome-lysosome and homotypic lysosome fusion in alveolar macrophages.

Q8R2Z3	S26A7_MOUSE	Anion exchange transporter	12736153	Identification of a basolateral Cl-/HCO3- exchanger specific to gastric parietal cells.

Q921A4	CYGB_RAT	Cytoglobin	11320098	Characterization of a stellate cell activation-associated protein (STAP) with peroxidase activity found in rat hepatic stellate cells.

Q13402	MYO7A_HUMAN	Myosin-VIIa	11964381	MyRIP, a novel Rab effector, enables myosin VIIa recruitment to retinal melanosomes.

Q03705	CG121_YEAST	Protein CGI121	16874308	Yeast homolog of a cancer-testis antigen defines a new transcription complex.

O35242	FAN_MOUSE	Protein FAN	10228161	Impaired neutral sphingomyelinase activation and cutaneous barrier repair in FAN-deficient mice.

P83056	KNL1_BOMVA	Kininogen-1	12230583	Novel bradykinins and their precursor cDNAs from European yellow- bellied toad (Bombina variegata) skin.

O13865	YDU4_SCHPO	Uncharacterized protein C1B1.04c, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O75575	RPC9_HUMAN	DNA-directed RNA polymerase III subunit RPC9	10067875	Testes exhibit elevated expression of calcitonin gene-related peptide receptor component protein.

O74700	TIM9_YEAST	Mitochondrial import inner membrane translocase subunit TIM9	9822593	Tim9p, an essential partner subunit of Tim10p for the import of mitochondrial carrier proteins.

O60687	SRPX2_HUMAN	Sushi repeat-containing protein SRPX2	19065654	SRPX2 is overexpressed in gastric cancer and promotes cellular migration and adhesion.

Q9RY80	DDRB_DEIRA	Single-stranded DNA-binding protein DdrB	15454524	Analysis of Deinococcus radiodurans's transcriptional response to ionizing radiation and desiccation reveals novel proteins that contribute to extreme radioresistance.

O96000	NDUBA_HUMAN	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10	9878551	cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed.

Q9UNQ0	ABCG2_HUMAN	ATP-binding cassette sub-family G member 2	9861027	A multidrug resistance transporter from human MCF-7 breast cancer cells.

Q9BXC9	BBS2_HUMAN	Bardet-Biedl syndrome 2 protein	17574030	A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis.

Q13153	PAK1_HUMAN	Serine/threonine-protein kinase PAK 1	18716323	Scrib regulates PAK activity during the cell migration process.

Q6WNK7	SUS1_YEAST	Protein SUS1	18667528	The THP1-SAC3-SUS1-CDC31 complex works in transcription elongation- mRNA export preventing RNA-mediated genome instability.

Q9SJI8	MBF1A_ARATH	Multiprotein-bridging factor 1a	16283071	Transcriptional coactivator MBF1s from Arabidopsis predominantly localize in nucleolus.

P17084	COL_RAT	Colipase	8203536	Rat pancreatic lipase and two related proteins: enzymatic properties and mRNA expression during development.

P36639	8ODP_HUMAN	7,8-dihydro-8-oxoguanine triphosphatase	7713500	Genomic structure and chromosome location of the human mutT homologue gene MTH1 encoding 8-oxo-dGTPase for prevention of A:T to C:G transversion.

P54762	EPHB1_HUMAN	Ephrin type-B receptor 1	8666391	cDNA cloning, molecular characterization, and chromosomal localization of NET(EPHT2), a human EPH-related receptor protein- tyrosine kinase gene preferentially expressed in brain.

Q94AS9	CNGC4_ARATH	Cyclic nucleotide-gated ion channel 4	12566578	HLM1, an essential signaling component in the hypersensitive response, is a member of the cyclic nucleotide-gated channel ion channel family.

Q91V88	NPNT_MOUSE	Nephronectin	11546798	Molecular cloning of POEM: a novel adhesion molecule that interacts with alpha8beta1 integrin.

P49747	COMP_HUMAN	Cartilage oligomeric matrix protein	17993464	Cartilage oligomeric matrix protein protects cells against death by elevating members of the IAP family of survival proteins.

Q9NL29	EAT20_CAEEL	Abnormal pharyngeal pumping eat-20	10655217	EAT-20, a novel transmembrane protein with EGF motifs, is required for efficient feeding in Caenorhabditis elegans.

Q96ST3	SIN3A_HUMAN	Paired amphipathic helix protein Sin3a	14525983	DACH1 inhibits transforming growth factor-beta signaling through binding Smad4.

Q8K3P4	MSI1H_RAT	RNA-binding protein Musashi homolog 1	12205668	Differential expression of Musashi1 and nestin in the adult rat hippocampus after ischemia.

P00163	CYB_YEAST	Cytochrome b	10873857	Structure at 2.3 A resolution of the cytochrome bc1 complex from the yeast Saccharomyces cerevisiae co-crystallized with an antibody Fv fragment.

P83545	CHY1_PAGMA	Chrysophsin-1	12581207	Purification and characterization of three isoforms of chrysophsin, a novel antimicrobial peptide in the gills of the red sea bream, Chrysophrys major.

Q9UIV8	SPB13_HUMAN	Serpin B13	10512713	Cloning and characterization of hurpin (Protease Inhibitor 13): a new skin specific, UV-repressible serine proteinase inhibitor of the ovalbumin serpin family.

P40038	PCL6_YEAST	PHO85 cyclin-6	11602261	The yeast cyclins Pcl6p and Pcl7p are involved in the control of glycogen storage by the cyclin-dependent protein kinase Pho85p.

O00220	TR10A_HUMAN	Tumor necrosis factor receptor superfamily member 10A	9082980	The receptor for the cytotoxic ligand TRAIL.

P24893	COX1_CAEEL	Cytochrome c oxidase subunit 1	1551572	The mitochondrial genomes of two nematodes, Caenorhabditis elegans and Ascaris suum.

Q9Y705	ALP4_SCHPO	Spindle pole body component alp4	11080156	The fission yeast gamma-tubulin complex is required in G(1) phase and is a component of the spindle assembly checkpoint.

O94418	MUG87_SCHPO	Meiotically up-regulated gene 87 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P62081	RS7_HUMAN	40S ribosomal protein S7	8522193	The human ribosomal protein S7-encoding gene: isolation, structure and localization in 2p25.

Q9Z2K5	LST8_RAT	Target of rapamycin complex subunit LST8	11182770	Insulin regulation of a novel WD-40 repeat protein in adipocytes.

O74896	YQEC_SCHPO	Uncharacterized protein C576.12c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q03834	MSH6_YEAST	DNA mismatch repair protein MSH6	10066781	Saccharomyces cerevisiae MSH2/6 complex interacts with Holliday junctions and facilitates their cleavage by phage resolution enzymes.

Q04599	RM01_YEAST	54S ribosomal protein L1, mitochondrial	12392552	Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components.

Q7Z7G1	CLNK_HUMAN	Cytokine-dependent hematopoietic cell linker	10744659	A BASH/SLP-76-related adaptor protein MIST/Clnk involved in IgE receptor-mediated mast cell degranulation.

P70041	CER1_XENLA	Cerberus	12885561	Coordination of BMP-3b and cerberus is required for head formation of Xenopus embryos.

Q12126	CRK1_SCHPO	Serine/threonine-protein kinase crk1	8557037	Identification of a cdk-activating kinase in fission yeast.

P38218	POA1_YEAST	ADP-ribose 1''-phosphate phosphatase	15684411	A highly specific phosphatase that acts on ADP-ribose 1''-phosphate, a metabolite of tRNA splicing in Saccharomyces cerevisiae.

P36897	TGFR1_HUMAN	TGF-beta receptor type-1	17099224	Potentiation of Smad-mediated transcriptional activation by the RNA- binding protein RBPMS.

Q9VLT5	POE_DROME	Protein purity of essence	11517334	Control of Drosophila perineurial glial growth by interacting neurotransmitter-mediated signaling pathways.

Q9Y2P5	S27A5_HUMAN	Bile acyl-CoA synthetase	11980911	Participation of two members of the very long-chain acyl-CoA synthetase family in bile acid synthesis and recycling.

Q9SAH0	MRS2A_ARATH	Magnesium transporter MRS2-10	19966073	A root-expressed magnesium transporter of the MRS2/MGT gene family in Arabidopsis thaliana allows for growth in low-Mg2+ environments.

Q8WVV9	HNRLL_HUMAN	Heterogeneous nuclear ribonucleoprotein L-like	18669861	Regulation of CD45 alternative splicing by heterogeneous ribonucleoprotein, hnRNPLL.

Q99L60	VATC2_MOUSE	V-type proton ATPase subunit C 2	12527205	Diversity of mouse proton-translocating ATPase: presence of multiple isoforms of the C, d and G subunits.

O75840	KLF7_HUMAN	Krueppel-like factor 7	9774444	Cloning the cDNA for a new human zinc finger protein defines a group of closely related Krueppel-like transcription factors.

Q14500	IRK12_HUMAN	ATP-sensitive inward rectifier potassium channel 12	8647284	Kir2.2v: a possible negative regulator of the inwardly rectifying K+ channel Kir2.2.

Q91XV7	TM158_RAT	Transmembrane protein 158	11399754	Identification and molecular cloning of a novel brain-specific receptor protein that binds to brain injury-derived neurotrophic peptide. Possible role for neuronal survival.

P00492	HPRT_HUMAN	Hypoxanthine-guanine phosphoribosyltransferase	8044844	The crystal structure of human hypoxanthine-guanine phosphoribosyltransferase with bound GMP.

Q8K2C6	SIRT5_MOUSE	NAD-dependent deacetylase sirtuin-5	19410549	SIRT5 Deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle.

Q9XZI6	PICA_CAEEL	Phosphatidylinositol-binding clathrin assembly protein unc-11	10397769	UNC-11, a Caenorhabditis elegans AP180 homologue, regulates the size and protein composition of synaptic vesicles.

Q8R3C6	RBM19_MOUSE	Probable RNA-binding protein 19	16027046	Rbm19 is a nucleolar protein expressed in crypt/progenitor cells of the intestinal epithelium.

Q86UE4	LYRIC_HUMAN	Protein LYRIC	18316612	Molecular basis of nuclear factor-kappaB activation by astrocyte elevated gene-1.

Q9Y240	CLC11_HUMAN	C-type lectin domain family 11 member A	9442024	Molecular cloning of a new secreted sulfated mucin-like protein with a C-type lectin domain that is expressed in lymphoblastic cells.

Q9UNS1	TIM_HUMAN	Protein timeless homolog	15798197	Coupling of human circadian and cell cycles by the timeless protein.

Q8NK89	ABFB_ASPKA	Alpha-N-arabinofuranosidase B	16233515	Role of two alpha-L-arabinofuranosidases in arabinoxylan degradation and characteristics of the encoding genes from shochu koji molds, Aspergillus kawachii and Aspergillus awamori.

Q92681	RSCA1_HUMAN	Regulatory solute carrier protein family 1 member 1	8836035	The human gene of a protein that modifies Na(+)-D-glucose co- transport.

Q96FW1	OTUB1_HUMAN	Ubiquitin thioesterase OTUB1	18954305	Structural basis and specificity of human otubain 1-mediated deubiquitination.

Q9BUN8	DERL1_HUMAN	Derlin-1	15215856	A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol.

O94305	YJI5_SCHPO	Probable serine hydrolase C5E4.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O82503	CRF1_ARATH	Ethylene-responsive transcription factor CRF1	16832061	A subset of Arabidopsis AP2 transcription factors mediates cytokinin responses in concert with a two-component pathway.

Q12449	AHA1_YEAST	Hsp90 co-chaperone AHA1	12504007	Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1.

Q8IIG7	YPF05_PLAF7	Uncharacterized protein PF11_0207	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

Q9Z1T6	FYV1_MOUSE	1-phosphatidylinositol-3-phosphate 5-kinase	9858586	Cloning, characterization, and expression of a novel Zn2+-binding FYVE finger-containing phosphoinositide kinase in insulin-sensitive cells.

P07834	CDC4_YEAST	Cell division control protein 4	10409741	Cdc4, a protein required for the onset of S phase, serves an essential function during G(2)/M transition in Saccharomyces cerevisiae.

P51857	AK1D1_HUMAN	3-oxo-5-beta-steroid 4-dehydrogenase	7508385	Cloning and expression of cDNA of human delta 4-3-oxosteroid 5 beta- reductase and substrate specificity of the expressed enzyme.

O43435	TBX1_HUMAN	T-box transcription factor TBX1	9268629	Isolation and characterization of a gene from the DiGeorge chromosomal region homologous to the mouse Tbx1 gene.

P49590	SYHM_HUMAN	Probable histidyl-tRNA synthetase, mitochondrial	7755634	A novel gene oriented in a head-to-head configuration with the human histidyl-tRNA synthetase (HRS) gene encodes an mRNA that predicts a polypeptide homologous to HRS.

O74958	MMI1_SCHPO	YTH domain-containing protein mmi1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UBT2	SAE2_HUMAN	SUMO-activating enzyme subunit 2	20164921	Active site remodelling accompanies thioester bond formation in the SUMO E1.

P16649	TUP1_YEAST	General transcriptional corepressor TUP1	10722672	Hrs1/Med3 is a Cyc8-Tup1 corepressor target in the RNA polymerase II holoenzyme.

Q9CAD0	EGL1_ARATH	Transcription factor EGL1	12917293	A network of redundant bHLH proteins functions in all TTG1-dependent pathways of Arabidopsis.

Q39221	STLP2_ARATH	SEC12-like protein 2	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q8VC88	GRAN_MOUSE	Grancalcin	12529388	Granulocyte function in grancalcin-deficient mice.

P39176	ERFK_ECOLI	Probable L,D-transpeptidase ErfK/SrfK	18456808	Identification of the L,D-transpeptidases for peptidoglycan cross- linking in Escherichia coli.

P30821	P25_SCHPO	P25 protein	7929079	Brefeldin A sensitivity and resistance in Schizosaccharomyces pombe. Isolation of multiple genes conferring resistance.

P51114	FXR1_HUMAN	Fragile X mental retardation syndrome-related protein 1	7781595	FXR1, an autosomal homolog of the fragile X mental retardation gene.

Q8UUY8	ADRB2_ONCMY	Beta-2 adrenergic receptor	11737201	A putative beta2-adrenoceptor from the rainbow trout (Oncorhynuchus mykiss). Molecular characterization and pharmacology.

P47131	YJ55_YEAST	UPF0136 membrane protein YJR085C	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P13195	HEM1_RAT	5-aminolevulinate synthase, nonspecific, mitochondrial	3182776	Structure, turnover, and heme-mediated suppression of the level of mRNA encoding rat liver delta-aminolevulinate synthase.

P25632	RSC6_YEAST	Chromatin structure-remodeling complex protein RSC6	12183366	Chromatin remodeling by RSC involves ATP-dependent DNA translocation.

O14140	DSS1_SCHPO	mRNA export factor dss1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9FLC8	C79A2_ARATH	Phenylalanine N-hydroxylase	10799553	Cytochrome P450 CYP79A2 from Arabidopsis thaliana L. catalyzes the conversion of L-phenylalanine to phenylacetaldoxime in the biosynthesis of benzylglucosinolate.

Q9JJY3	NSMA2_MOUSE	Sphingomyelin phosphodiesterase 3	15764706	Neutral sphingomyelinase 2 (smpd3) in the control of postnatal growth and development.

P26435	NTCP_RAT	Sodium/bile acid cotransporter	1961729	Functional expression cloning and characterization of the hepatocyte Na+/bile acid cotransport system.

Q640N1	AEBP1_MOUSE	Adipocyte enhancer-binding protein 1	7477299	A eukaryotic transcriptional repressor with carboxypeptidase activity.

Q01968	OCRL_HUMAN	Inositol polyphosphate 5-phosphatase OCRL-1	7761412	The protein deficient in Lowe syndrome is a phosphatidylinositol-4,5- bisphosphate 5-phosphatase.

Q8W585	FTSH8_ARATH	ATP-dependent zinc metalloprotease FTSH 8, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

P33441	MFT1_YEAST	THO complex subunit MFT1	12093753	The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability.

Q0KI50	DMDD_DROME	Dystrophin, isoform D	17355978	A putative Src homology 3 domain binding motif but not the C-terminal dystrophin WW domain binding motif is required for dystroglycan function in cellular polarity in Drosophila.

Q9LG05	WRK10_ARATH	Probable WRKY transcription factor 10	16293693	MINISEED3 (MINI3), a WRKY family gene, and HAIKU2 (IKU2), a leucine- rich repeat (LRR) KINASE gene, are regulators of seed size in Arabidopsis.

O14788	TNF11_HUMAN	Tumor necrosis factor ligand superfamily member 11	9568710	Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation.

P69852	HSK3_YEAST	DASH complex subunit HSK3	15664196	Formation of a dynamic kinetochore-microtubule interface through assembly of the Dam1 ring complex.

Q9IAV3	HHEX_DANRE	Hematopoietically-expressed homeobox protein hhex	11477693	Zebrafish hhex regulates liver development and digestive organ chirality.

Q9XV66	UNC80_CAEEL	Protein unc-80	17825559	UNC-80 and the NCA ion channels contribute to endocytosis defects in synaptojanin mutants.

P12282	MOEB_ECOLI	Sulfur carrier protein moaD adenylyltransferase	11713534	Mechanism of ubiquitin activation revealed by the structure of a bacterial MoeB-MoaD complex.

O54942	CLD5_MOUSE	Claudin-5	10601346	Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins.

Q01167	FOXK2_HUMAN	Forkhead box protein K2	1339390	Characterization and chromosomal mapping of the gene encoding the cellular DNA binding protein ILF.

O42634	DMC1_SCHPO	Meiotic recombination protein dmc1	15899844	Fission yeast rad51 and dmc1, two efficient DNA recombinases forming helical nucleoprotein filaments.

Q13769	THOC5_HUMAN	THO complex subunit 5 homolog	15998806	Recruitment of the human TREX complex to mRNA during splicing.

Q9H0H5	RGAP1_HUMAN	Rac GTPase-activating protein 1	10979956	MgcRacGAP is involved in the control of growth and differentiation of hematopoietic cells.

Q9VLD6	BOREA_DROME	Borealin	16224046	Loss of Drosophila borealin causes polyploidy, delayed apoptosis and abnormal tissue development.

Q62315	JARD2_MOUSE	Protein Jumonji	17521633	Characterization of zinc finger protein 496 that interacts with Jumonji/JARID2.

Q9R0C8	VAV3_MOUSE	Guanine nucleotide exchange factor VAV3	16782872	Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis.

Q03246	RT17_YEAST	37S ribosomal protein S17, mitochondrial	12392552	Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components.

P0AC19	FOLX_ECOLI	D-erythro-7,8-dihydroneopterin triphosphate epimerase	9651328	Biosynthesis of pteridines in Escherichia coli. Structural and mechanistic similarity of dihydroneopterin-triphosphate epimerase and dihydroneopterin aldolase.

P37623	ACPT_ECOLI	4'-phosphopantetheinyl transferase AcpT	8939709	A new enzyme superfamily -- the phosphopantetheinyl transferases.

Q9BRQ8	AIFM2_HUMAN	Apoptosis-inducing factor 2	11980907	AMID, an apoptosis-inducing factor-homologous mitochondrion- associated protein, induces caspase-independent apoptosis.

Q9JKD9	ZBT32_MOUSE	Zinc finger and BTB domain-containing protein 32	10755619	ROG, repressor of GATA, regulates the expression of cytokine genes.

Q9VBV3	TAKT_DROME	Protein takeout	10892651	The Drosophila takeout gene is a novel molecular link between circadian rhythms and feeding behavior.

Q13485	SMAD4_HUMAN	Mothers against decapentaplegic homolog 4	14525983	DACH1 inhibits transforming growth factor-beta signaling through binding Smad4.

P46032	PTR2_ARATH	Peptide transporter PTR2	16618929	Mapping the Arabidopsis organelle proteome.

Q8GSA7	CMTA3_ARATH	Calmodulin-binding transcription activator 3	11782485	Genes encoding calmodulin-binding proteins in the Arabidopsis genome.

P35789	ZNF93_HUMAN	Zinc finger protein 93	2023909	The evolutionarily conserved Kruppel-associated box domain defines a subfamily of eukaryotic multifingered proteins.

Q5FYB1	ARSI_HUMAN	Arylsulfatase I	16174644	Sulfatases and sulfatase modifying factors: an exclusive and promiscuous relationship.

P29597	TYK2_HUMAN	Non-receptor tyrosine-protein kinase TYK2	2216457	TYK2, prototype of a novel class of non-receptor tyrosine kinase genes.

P12277	KCRB_HUMAN	Creatine kinase B-type	3034271	Human creatine kinase: isolation and sequence analysis of cDNA clones for the B subunit, development of subunit specific probes and determination of gene copy number.

Q9FGM1	PYL8_ARATH	Abscisic acid receptor PYL8	19624469	Modulation of drought resistance by the abscisic acid receptor PYL5 through inhibition of clade A PP2Cs.

P70033	NR6A1_XENLA	Nuclear receptor subfamily 6 group A member 1	10349627	Anteroposterior patterning and organogenesis of Xenopus laevis require a correct dose of germ cell nuclear factor (xGCNF).

O59682	LCB1_SCHPO	Serine palmitoyltransferase 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q75VN4	H2B_RHASC	Histone H2B	14651982	A protein with antimicrobial activity in the skin of Schlegel's green tree frog Rhacophorus schlegelii (Rhacophoridae) identified as histone H2B.

P38084	BAP2_YEAST	Leu/Val/Ile amino-acid permease	10654085	Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae.

Q10169	DSK2_SCHPO	Deubiquitination-protection protein dph1	12560082	Ubiquitin binding proteins protect ubiquitin conjugates from disassembly.

P0AAR3	YBAK_ECOLI	Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase ybaK	15886196	The bacterial YbaK protein is a Cys-tRNAPro and Cys-tRNA Cys deacylase.

Q00141	NCPR_ASPNG	NADPH--cytochrome P450 reductase	11594739	Purification and characterization of benzoate-para-hydroxylase, a cytochrome P450 (CYP53A1), from Aspergillus niger.

Q9LN71	RING1_ARATH	E3 ubiquitin-protein ligase At1g12760	15644464	Functional analysis of the RING-type ubiquitin ligase family of Arabidopsis.

P30793	GCH1_HUMAN	GTP cyclohydrolase 1	12607127	Role of human GTP cyclohydrolase I and its regulatory protein in tetrahydrobiopterin metabolism.

P15144	AMPN_HUMAN	Aminopeptidase N	2564851	Human myeloid plasma membrane glycoprotein CD13 (gp150) is identical to aminopeptidase N.

B2RY04	DOCK5_MOUSE	Dedicator of cytokinesis protein 5	18396277	Mutation of Dock5, a member of the guanine exchange factor Dock180 superfamily, in the rupture of lens cataract mouse.

Q6PDV7	RL10_RAT	60S ribosomal protein L10	8780716	The primary structure of rat ribosomal protein L10: relationship to a Jun-binding protein and to a putative Wilms' tumor suppressor.

Q5BFG8	BGLB_EMENI	Beta-glucosidase B	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

O13846	SCS7_SCHPO	Ceramide very long chain fatty acid hydroxylase-like protein C19G12.08	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P36955	PEDF_HUMAN	Pigment epithelium-derived factor	8473338	Senescent WI-38 cells fail to express EPC-1, a gene induced in young cells upon entry into the G0 state.

A1L1N5	HN1BA_DANRE	Hepatocyte nuclear factor 1-beta-A	11731484	vhnf1, the MODY5 and familial GCKD-associated gene, regulates regional specification of the zebrafish gut, pronephros, and hindbrain.

Q64FW2	RETST_MOUSE	All-trans-retinol 13,14-reductase	15358783	Identification of all-trans-retinol: all-trans-13,14-dihydroretinol saturase.

Q99996	AKAP9_HUMAN	A-kinase anchor protein 9	12163479	AKAP350 at the Golgi apparatus. II. Association of AKAP350 with a novel chloride intracellular channel (CLIC) family member.

Q9EPY0	CARD9_RAT	Caspase recruitment domain-containing protein 9	11053425	CARD9 is a novel caspase recruitment domain-containing protein that interacts with Bcl10/CLAP and activates NF-kappa B.

Q8L7F9	B3GTF_ARATH	Beta-1,3-galactosyltransferase 15	17630273	A unique beta-1,3-galactosyltransferase is indispensable for the biosynthesis of N-glycans containing Lewis a structures in Arabidopsis thaliana.

Q96BS2	TESC_HUMAN	Tescalcin	12809501	The Na+/H+ exchanger cytoplasmic tail: structure, function, and interactions with tescalcin.

P53693	RDS1_SCHPO	Protein rds1	7565608	Schizosaccharomyces pombe rds1, an adenine-repressible gene regulated by glucose, ammonium, phosphate, carbon dioxide and temperature.

P05067	A4_HUMAN	Amyloid beta A4 protein	11278849	Beta-amyloid peptide-induced apoptosis regulated by a novel protein containing a G protein activation module.

Q9NYX4	CALY_HUMAN	Neuron-specific vesicular protein calcyon	16595675	Calcyon, a novel partner of clathrin light chain, stimulates clathrin-mediated endocytosis.

Q9UDV7	ZN282_HUMAN	Zinc finger protein 282	9396811	HUB1, a novel Kruppel type zinc finger protein, represses the human T cell leukemia virus type I long terminal repeat-mediated expression.

Q76IQ4	GHRL_ONCMY	Ghrelin	12970156	Peptide purification, complementary deoxyribonucleic acid (DNA) and genomic DNA cloning, and functional characterization of ghrelin in rainbow trout.

P70502	SO1A3_RAT	Solute carrier organic anion transporter family member 1A3	8702823	Cloning and functional characterization of a novel rat organic anion transporter mediating basolateral uptake of methotrexate in the kidney.

Q18PE0	DOK7_MOUSE	Protein Dok-7	16794080	The muscle protein Dok-7 is essential for neuromuscular synaptogenesis.

Q8CHK2	REL3_MOUSE	Relaxin-3	11689565	Human relaxin gene 3 (H3) and the equivalent mouse relaxin (M3) gene. Novel members of the relaxin peptide family.

Q14511	CASL_HUMAN	Enhancer of filamentation 1	8668148	Human enhancer of filamentation 1, a novel p130cas-like docking protein, associates with focal adhesion kinase and induces pseudohyphal growth in Saccharomyces cerevisiae.

P15873	PCNA_YEAST	Proliferating cell nuclear antigen	11545742	Interaction with PCNA is essential for yeast DNA polymerase eta function.

P02340	P53_MOUSE	Cellular tumor antigen p53	15526030	Axin stimulates p53 functions by activation of HIPK2 kinase through multimeric complex formation.

Q9HDX2	YKN3_SCHPO	Uncharacterized lactate 2-monooxygenase PB1A11.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P82350	SGCA_MOUSE	Alpha-sarcoglycan	9196068	Mouse adhalin: primary structure and expression during late stages of muscle differentiation in vitro.

Q06596	YAP8_YEAST	AP-1-like transcription factor YAP8	9234670	Isolation of three contiguous genes, ACR1, ACR2 and ACR3, involved in resistance to arsenic compounds in the yeast Saccharomyces cerevisiae.

P51142	DVL2_XENLA	Segment polarity protein dishevelled homolog DVL-2	10427095	Establishment of the dorsal-ventral axis in Xenopus embryos coincides with the dorsal enrichment of dishevelled that is dependent on cortical rotation.

P22696	ESS1_YEAST	Peptidyl-prolyl cis-trans isomerase ESS1	10899127	Cyclophilin A and Ess1 interact with and regulate silencing by the Sin3-Rpd3 histone deacetylase.

Q06349	YD370_YEAST	Uncharacterized protein YDR370C	14562095	Global analysis of protein localization in budding yeast.

Q9NQL9	DMRT3_HUMAN	Doublesex- and mab-3-related transcription factor 3	10729223	The region on 9p associated with 46,XY sex reversal contains several transcripts expressed in the urogenital system and a novel doublesex- related domain.

Q08754	BUD7_YEAST	Bud site selection protein 7	16498409	Arf1p, Chs5p and the ChAPs are required for export of specialized cargo from the Golgi.

P18089	ADA2B_HUMAN	Alpha-2B adrenergic receptor	2164221	Expansion of the alpha 2-adrenergic receptor family: cloning and characterization of a human alpha 2-adrenergic receptor subtype, the gene for which is located on chromosome 2.

P38251	RFC5_YEAST	Replication factor C subunit 5	12665596	Mechanical link between cohesion establishment and DNA replication: Ctf7p/Eco1p, a cohesion establishment factor, associates with three different replication factor C complexes.

Q54PA9	PRPSA_DICDI	Ribose-phosphate pyrophosphokinase A	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P63000	RAC1_HUMAN	Ras-related C3 botulinum toxin substrate 1	11090627	Structure of the TPR domain of p67phox in complex with Rac.GTP.

Q6P9S7	GLT10_MOUSE	Polypeptide N-acetylgalactosaminyltransferase 10	11278534	Cloning and characterization of a ninth member of the UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase family, ppGaNTase-T9.

P84881	IELK1_BAURF	Kunitz-type elastase inhibitor BrEI	16557451	A Kunitz-type glycosylated elastase inhibitor with one disulfide bridge.

Q9SB60	IPT4_ARATH	Adenylate isopentenyltransferase 4	14726522	Distinct isoprenoid origins of cis- and trans-zeatin biosyntheses in Arabidopsis.

P28778	RT06_YEAST	37S ribosomal protein MRP17, mitochondrial	12392552	Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components.

Q63068	PHAX_RAT	Phosphorylated adapter RNA export protein	8015392	Molecular cloning of a resiniferatoxin-binding protein.

Q9NPC8	SIX2_HUMAN	Homeobox protein SIX2	10773454	Structure, mapping and expression of the human gene encoding the homeodomain protein, SIX2.

P30011	NADC_ECOLI	Nicotinate-nucleotide pyrophosphorylase [carboxylating]	8561507	The sequencing expression, purification, and steady-state kinetic analysis of quinolinate phosphoribosyl transferase from Escherichia coli.

Q05066	SRY_HUMAN	Sex-determining region Y protein	1425584	SRY, like HMG1, recognizes sharp angles in DNA.

Q14188	TFDP2_HUMAN	Transcription factor Dp-2	7784053	Cloning and characterization of human DP2, a novel dimerization partner of E2F.

Q04828	AK1C1_HUMAN	Aldo-keto reductase family 1 member C1	8486699	cDNA cloning and expression of the human hepatic bile acid-binding protein. A member of the monomeric reductase gene family.

P47131	YJ55_YEAST	UPF0136 membrane protein YJR085C	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Q925H0	ACCN1_MOUSE	Amiloride-sensitive cation channel 1, neuronal	15537887	Acid-sensing ion channel 2 contributes a major component to acid- evoked excitatory responses in spiral ganglion neurons and plays a role in noise susceptibility of mice.

Q8RX22	MIP1_ARATH	MND1-interacting protein 1	19187040	A novel ATM dependant X-ray inducible gene is essential for both plant meiosis and gametogenesis.

C0LGG6	Y5189_ARATH	Probable LRR receptor-like protein kinase At1g51890	16678099	Specific bacterial suppressors of MAMP signaling upstream of MAPKKK in Arabidopsis innate immunity.

Q9LZ03	TOP6A_ARATH	DNA topoisomerase 6 subunit A	12401175	DNA topoisomerase VI is essential for endoreduplication in Arabidopsis.

Q39123	ATHB8_ARATH	Homeobox-leucine zipper protein ATHB-8	11402194	The arabidopsis ATHB-8 HD-zip protein acts as a differentiation- promoting transcription factor of the vascular meristems.

O65621	CADH6_ARATH	Probable cinnamyl alcohol dehydrogenase 6	17467016	Expression of cinnamyl alcohol dehydrogenases and their putative homologues during Arabidopsis thaliana growth and development: lessons for database annotations?

Q9VEX5	M89BB_DROME	Cell cycle regulator Mat89Bb	15737938	Drosophila genome-scale screen for PAN GU kinase substrates identifies Mat89Bb as a cell cycle regulator.

Q63638	SPEG_RAT	Striated muscle-specific serine/threonine-protein kinase	8663449	APEG-1, a novel gene preferentially expressed in aortic smooth muscle cells, is down-regulated by vascular injury.

Q9Y4K4	M4K5_HUMAN	Mitogen-activated protein kinase kinase kinase kinase 5	9788432	The germinal center kinase (GCK)-related protein kinases HPK1 and KHS are candidates for highly selective signal transducers of Crk family adapter proteins.

P43571	BST1_YEAST	GPI inositol-deacylase	8862519	Genes that control the fidelity of endoplasmic reticulum to Golgi transport identified as suppressors of vesicle budding mutations.

Q99759	M3K3_HUMAN	Mitogen-activated protein kinase kinase kinase 3	9006902	Direct activation of the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by an inducible mitogen-activated protein kinase/ERK kinase kinase 3 (MEKK) derivative.

Q04603	DPB4_YEAST	DNA polymerase epsilon subunit D	14673157	Noncompetitive counteractions of DNA polymerase epsilon and ISW2/yCHRAC for epigenetic inheritance of telomere position effect in Saccharomyces cerevisiae.

O94641	HS104_SCHPO	Heat shock protein 104	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q00796	DHSO_HUMAN	Sorbitol dehydrogenase	12962626	X-ray crystallographic and kinetic studies of human sorbitol dehydrogenase.

O00204	ST2B1_HUMAN	Sulfotransferase family cytosolic 2B member 1	12145317	Mutational analysis of human hydroxysteroid sulfotransferase SULT2B1 isoforms reveals that exon 1B of the SULT2B1 gene produces cholesterol sulfotransferase, whereas exon 1A yields pregnenolone sulfotransferase.

Q5RKR3	ISLR2_MOUSE	Immunoglobulin superfamily containing leucine-rich repeat protein 2	19755105	LIG family receptor tyrosine kinase-associated proteins modulate growth factor signals during neural development.

P37353	MENE_ECOLI	2-succinylbenzoate--CoA ligase	8626063	Menaquinone (vitamin K2) biosynthesis: localization and characterization of the menE gene from Escherichia coli.

Q8GYB8	OPR2_ARATH	12-oxophytodienoate reductase 2	10333582	Structure and regulation of OPR1 and OPR2, two closely related genes encoding 12-oxophytodienoic acid-10,11-reductases from Arabidopsis thaliana.

P22523	MUKB_ECOLI	Chromosome partition protein mukB	9688555	Interaction of the N-terminal domain of MukB with the bacterial tubulin homologue FtsZ.

Q5M834	DTBP1_RAT	Dysbindin	11316798	Dysbindin, a novel coiled-coil-containing protein that interacts with the dystrobrevins in muscle and brain.

P04913	H2B1_SCHPO	Histone H2B-alpha	16024659	A Rik1-associated, cullin-dependent E3 ubiquitin ligase is essential for heterochromatin formation.

Q9NS87	KIF15_HUMAN	Kinesin-like protein KIF15	10878014	The forkhead-associated domain of Ki-67 antigen interacts with the novel kinesin-like protein Hklp2.

Q3ZCQ8	TIM50_HUMAN	Mitochondrial import inner membrane translocase subunit TIM50	15044455	Tim50, a component of the mitochondrial translocator, regulates mitochondrial integrity and cell death.

Q02971	CADH7_ARATH	Cinnamyl alcohol dehydrogenase 7	1464303	Rapid activation of a novel plant defense gene is strictly dependent on the Arabidopsis RPM1 disease resistance locus.

Q4PSU4	AGL61_ARATH	Agamous-like MADS-box protein AGL61	18599653	AGL61 interacts with AGL80 and is required for central cell development in Arabidopsis.

P53916	TEP1_YEAST	Probable phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TEP1	11070083	TEP1, the yeast homolog of the human tumor suppressor gene PTEN/MMAC1/TEP1, is linked to the phosphatidylinositol pathway and plays a role in the developmental process of sporulation.

Q46AR9	ALAXM_METBF	Alanyl-tRNA editing protein AlaX-M	14663147	Trans-editing of mischarged tRNAs.

Q9UBU9	NXF1_HUMAN	Nuclear RNA export factor 1	11583626	Structural basis for the recognition of a nucleoporin FG repeat by the NTF2-like domain of the TAP/p15 mRNA nuclear export factor.

Q9WTY1	PDCD7_MOUSE	Programmed cell death protein 7	10087507	Molecular cloning, functional expression and chromosomal localization of a cDNA encoding a human Na+/nucleoside cotransporter (hCNT2) selective for purine nucleosides and uridine.

Q12296	MAM3_YEAST	Protein MAM3	15498024	Manganese toxicity and Saccharomyces cerevisiae Mam3p, a member of the ACDP (ancient conserved domain protein) family.

Q9JLH6	CK5P1_RAT	CDK5 regulatory subunit-associated protein 1	10721722	Cloning of three novel neuronal Cdk5 activator binding proteins.

O74469	YQC7_SCHPO	Exosome complex protein C1739.07	15148393	Cti1/C1D interacts with condensin SMC hinge and supports the DNA repair function of condensin.

O74859	APTX_SCHPO	Aprataxin-like protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q24475	RPR_DROME	Cell death protein rpr	8171319	Genetic control of programmed cell death in Drosophila.

Q9P7B4	YI13_SCHPO	Uncharacterized oxidoreductase C521.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q62920	PDLI5_RAT	PDZ and LIM domain protein 5	19900557	Postsynaptic PDLIM5/Enigma homolog binds SPAR and causes dendritic spine shrinkage.

Q07657	SHS1_YEAST	Seventh homolog of septin 1	9813092	The septins are required for the mitosis-specific activation of the Gin4 kinase.

Q54NB6	FKBP4_DICDI	FK506-binding protein 4	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

Q12374	NCA2_YEAST	Nuclear control of ATPase protein 2	7723016	NCA2, a second nuclear gene required for the control of mitochondrial synthesis of subunits 6 and 8 of ATP synthase in Saccharomyces cerevisiae.

Q15286	RAB35_HUMAN	Ras-related protein Rab-35	7811277	Molecular cloning of two small GTP-binding proteins from human skeletal muscle.

Q7SIB9	HIS6_THET8	Imidazole glycerol phosphate synthase subunit hisF	12417026	Structure of imidazole glycerol phosphate synthase from Thermus thermophilus HB8: open-closed conformational change and ammonia tunneling.

Q8WXG1	RSAD2_HUMAN	Radical S-adenosyl methionine domain-containing protein 2	16982913	TLR3 ligation activates an antiviral response in human fetal astrocytes: a role for viperin/cig5.

Q9QZ06	TOLIP_MOUSE	Toll-interacting protein	10854325	Tollip, a new component of the IL-1R1 pathway, links IRAK to the IL-1 receptor.

O75077	ADA23_HUMAN	Disintegrin and metalloproteinase domain-containing protein 23	9693107	Metalloproteinase-like, disintegrin-like, cysteine-rich proteins MDC2 and MDC3: novel human cellular disintegrins highly expressed in the brain.

P28778	RT06_YEAST	37S ribosomal protein MRP17, mitochondrial	9151978	Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae.

Q9JJ48	ZC3H8_MOUSE	Zinc finger CCCH domain-containing protein 8	11318609	Transcripts of Fliz1, a nuclear zinc finger protein, are expressed in discrete foci of the murine fetal liver.

O00623	PEX12_HUMAN	Peroxisome assembly protein 12	9090384	Isolation of the human PEX12 gene, mutated in group 3 of the peroxisome biogenesis disorders.

Q03694	INP1_YEAST	Inheritance of peroxisomes protein 1	15928207	Inp1p is a peroxisomal membrane protein required for peroxisome inheritance in Saccharomyces cerevisiae.

O09000	NCOA3_MOUSE	Nuclear receptor coactivator 3	10823921	The steroid receptor coactivator SRC-3 (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development.

Q20930	MIG17_CAEEL	ADAM family mig-17	16354716	The conserved oligomeric Golgi complex acts in organ morphogenesis via glycosylation of an ADAM protease in C. elegans.

Q63665	USF2_RAT	Upstream stimulatory factor 2	8576131	Immunochemical characterization and transacting properties of upstream stimulatory factor isoforms.

Q15582	BGH3_HUMAN	Transforming growth factor-beta-induced protein ig-h3	1388724	cDNA cloning and sequence analysis of beta ig-h3, a novel gene induced in a human adenocarcinoma cell line after treatment with transforming growth factor-beta.

Q9Y6A9	SPCS1_HUMAN	Signal peptidase complex subunit 1	8632014	Membrane topology of the 12- and the 25-kDa subunits of the mammalian signal peptidase complex.

Q63257	IL4RA_RAT	Interleukin-4 receptor subunit alpha	10525162	Identification of soluble interleukin-4 receptor in rat glomerular epithelial cells.

Q1MTN9	RLF2_SCHPO	Chromatin assembly factor 1 subunit rlf2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q04083	THI74_YEAST	Thiamine-repressible mitochondrial transport protein THI74	16850348	Pdc2 coordinates expression of the THI regulon in the yeast Saccharomyces cerevisiae.

P35222	CTNB1_HUMAN	Catenin beta-1	11590244	AlphaT-catenin: a novel tissue-specific beta-catenin-binding protein mediating strong cell-cell adhesion.

P02599	CALM_DICDI	Calmodulin	1493336	Inducible expression of calmodulin antisense RNA in Dictyostelium cells inhibits the completion of cytokinesis.

P14063	RM31_YEAST	54S ribosomal protein L31, mitochondrial	12392552	Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components.

P32916	SRPR_YEAST	Signal recognition particle receptor subunit alpha homolog	1327299	Signal recognition particle receptor is important for cell growth and protein secretion in Saccharomyces cerevisiae.

Q92331	VPS5_YEAST	Vacuolar protein sorting-associated protein 5	9700157	A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeast.

Q04149	MUS81_YEAST	Crossover junction endonuclease MUS81	11641278	Functional overlap between Sgs1-Top3 and the Mms4-Mus81 endonuclease.

P25338	YGB0_YEAST	Uncharacterized endoplasmic reticulum membrane protein YGL010W	14562095	Global analysis of protein localization in budding yeast.

P21570	ANGI_MOUSE	Angiogenin	8448182	Characterization and sequencing of rabbit, pig and mouse angiogenins: discernment of functionally important residues and regions.

A2AF47	DOC11_MOUSE	Dedicator of cytokinesis protein 11	15710388	Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes.

Q8LFP1	PRA1H_ARATH	PRA1 family protein H	18583532	The PRA1 gene family in Arabidopsis.

Q8N144	CXD3_HUMAN	Gap junction delta-3 protein	12154091	Molecular cloning, functional expression, and tissue distribution of a novel human gap junction-forming protein, connexin-31.9. Interaction with zona occludens protein-1.

P24472	GSTA4_MOUSE	Glutathione S-transferase A4	1426286	A subgroup of class alpha glutathione S-transferases. Cloning of cDNA for mouse lung glutathione S-transferase GST 5.7.

Q7TSD4	SPATL_MOUSE	Protein SPATIAL	11196687	Spatial, a gene expressed in thymic stromal cells, depends on three- dimensional thymus organization for its expression.

Q9Y5X4	NR2E3_HUMAN	Photoreceptor-specific nuclear receptor	10220376	Identification of a photoreceptor cell-specific nuclear receptor.

O13710	SMC5_SCHPO	Structural maintenance of chromosomes protein 5	15485909	Rad62 protein functionally and physically associates with the smc5/smc6 protein complex and is required for chromosome integrity and recombination repair in fission yeast.

O95755	RAB36_HUMAN	Ras-related protein Rab-36	9920784	Cloning and characterization of a novel Rab-family gene, Rab36, within the region at 22q11.2 that is homozygously deleted in malignant rhabdoid tumors.

P17140	CO4A2_CAEEL	Collagen alpha-2(IV) chain	7691828	Genetic identification, sequence, and alternative splicing of the Caenorhabditis elegans alpha 2(IV) collagen gene.

P22696	ESS1_YEAST	Peptidyl-prolyl cis-trans isomerase ESS1	9867817	Mutations in a peptidylprolyl-cis/trans-isomerase gene lead to a defect in 3'-end formation of a pre-mRNA in Saccharomyces cerevisiae.

Q08211	DHX9_HUMAN	ATP-dependent RNA helicase A	15355351	RNA helicase A interacts with nuclear factor kappaB p65 and functions as a transcriptional coactivator.

P85886	CA1AB_CONSP	Alpha-conotoxin SrIA/SrIB	17635581	Novel alpha-conotoxins from Conus spurius and the alpha-conotoxin EI share high-affinity potentiation and low-affinity inhibition of nicotinic acetylcholine receptors.

Q8VCF0	MAVS_MOUSE	Mitochondrial antiviral-signaling protein	18849341	FLN29 deficiency reveals its negative regulatory role in the Toll- like receptor (TLR) and retinoic acid-inducible gene I (RIG-I)-like helicase signaling pathway.

P42603	YGJV_ECOLI	Inner membrane protein ygjV	11867724	Rapid topology mapping of Escherichia coli inner-membrane proteins by prediction and PhoA/GFP fusion analysis.

P30337	CHIN_RAT	N-chimaerin	1445199	Developmental regulation and neuronal expression of the mRNA of rat n-chimaerin, a p21rac GAP:cDNA sequence.

Q64359	CNGA4_RAT	Cyclic nucleotide-gated cation channel alpha-4	7522482	A second subunit of the olfactory cyclic nucleotide-gated channel confers high sensitivity to cAMP.

Q12368	SNU23_YEAST	23 kDa U4/U6.U5 small nuclear ribonucleoprotein component	10449419	Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6.U5] tri-snRNP.

O43638	FOXS1_HUMAN	Forkhead box protein S1	9325056	Chromosome localization, sequence analysis, and expression pattern identify FKHL 18 as a novel human forkhead gene.

Q9NZJ5	E2AK3_HUMAN	Eukaryotic translation initiation factor 2-alpha kinase 3	10026192	Characterization of a mutant pancreatic eIF-2alpha kinase, PEK, and co-localization with somatostatin in islet delta cells.

Q9V8P9	TOPRS_DROME	E3 ubiquitin-protein ligase Topors	16209949	The ubiquitin ligase dTopors directs the nuclear organization of a chromatin insulator.

Q9W1V6	PRPD3_DROME	Diphenoloxidase subunit A3	12834045	Prophenol oxidase A3 in Drosophila melanogaster: activation and the PCR-based cDNA sequence.

P55317	FOXA1_HUMAN	Hepatocyte nuclear factor 3-alpha	16331276	BRCA1 and FOXA1 proteins coregulate the expression of the cell cycle- dependent kinase inhibitor p27(Kip1).

P42736	RAP23_ARATH	Ethylene-responsive transcription factor RAP2-3	18836139	Ethylene- and pathogen-inducible Arabidopsis acyl-CoA-binding protein 4 interacts with an ethylene-responsive element binding protein.

Q21341	LET99_CAEEL	Protein let-99	12223405	LET-99 determines spindle position and is asymmetrically enriched in response to PAR polarity cues in C. elegans embryos.

Q05930	MDM30_YEAST	Mitochondrial distribution and morphology protein 30	11907266	Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae.

O49675	CCD4_ARATH	Probable carotenoid cleavage dioxygenase 4, chloroplastic	15340011	Arabidopsis VARIEGATED 3 encodes a chloroplast-targeted, zinc-finger protein required for chloroplast and palisade cell development.

O57437	DAZLA_XENLA	Deleted in azoospermia-like-A	9486791	A Xenopus DAZ-like gene encodes an RNA component of germ plasm and is a functional homologue of Drosophila boule.

P32597	STH1_YEAST	Nuclear protein STH1/NPS1	10619019	Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains.

Q60994	ADIPO_MOUSE	Adiponectin	11479628	The adipocyte-secreted protein Acrp30 enhances hepatic insulin action.

Q14160	SCRIB_HUMAN	Protein scribble homolog	18716323	Scrib regulates PAK activity during the cell migration process.

Q21921	SIRT1_CAEEL	NAD-dependent deacetylase SIR2 homolog	16280150	Overlapping and distinct functions for a Caenorhabditis elegans SIR2 and DAF-16/FOXO.

P39825	PROF_SCHPO	Profilin	8207058	The Schizosaccharomyces pombe cdc3+ gene encodes a profilin essential for cytokinesis.

P41151	HFA1A_ARATH	Heat stress transcription factor A-1a	7948881	Arabidopsis heat shock factor: isolation and characterization of the gene and the recombinant protein.

Q93971	TRPG_CAEEL	Transient receptor potential channel	9383054	gon-2, a gene required for gonadogenesis in Caenorhabditis elegans.

Q24570	GRIM_DROME	Cell death protein Grim	8698237	Grim, a novel cell death gene in Drosophila.

O75081	MTG16_HUMAN	Protein CBFA2T3	15231665	AML1-ETO decreases ETO-2 (MTG16) interactions with nuclear receptor corepressor, an effect that impairs granulocyte differentiation.

P86010	CUTI1_COLKA	Cutinase 1	17043825	Purification and identification of cutinases from Colletotrichum kahawae and Colletotrichum gloeosporioides.

P49025	CTRO_MOUSE	Citron Rho-interacting kinase	11086988	Defective neurogenesis in citron kinase knockout mice by altered cytokinesis and massive apoptosis.

P11487	FGF3_HUMAN	Fibroblast growth factor 3	2470007	Sequence organization of the human int-2 gene and its expression in teratocarcinoma cells.

Q92600	RCD1_HUMAN	Cell differentiation protein RCD1 homolog	9447985	Novel factor highly conserved among eukaryotes controls sexual development in fission yeast.

O33244	PSA_MYCTU	Proteasome subunit alpha	19759536	Inhibitors selective for mycobacterial versus human proteasomes.

Q3E7B0	YE053_YEAST	Uncharacterized protein YER053C-A	14562095	Global analysis of protein localization in budding yeast.

Q02776	TIM50_YEAST	Mitochondrial import inner membrane translocase subunit TIM50	15797382	Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17.

Q13588	GRAP_HUMAN	GRB2-related adapter protein	8647802	Grap is a novel SH3-SH2-SH3 adaptor protein that couples tyrosine kinases to the Ras pathway.

Q9UT72	RFP2_SCHPO	E3 ubiquitin-protein ligase complex slx8-rfp subunit rfp2	17762864	Conserved function of RNF4 family proteins in eukaryotes: targeting a ubiquitin ligase to SUMOylated proteins.

P38282	SP381_YEAST	Pre-mRNA-splicing factor SPP381	10449419	Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6.U5] tri-snRNP.

Q9C4B4	CSG_HALJP	Cell surface glycoprotein	9680334	Cloning and sequencing of the gene encoding the cell surface glycoprotein of Haloarcula japonica strain TR-1.

O73622	PAT_XENLA	Protein Pat	16216237	Xenopus Xpat protein is a major component of germ plasm and may function in its organisation and positioning.

P70349	HINT1_MOUSE	Histidine triad nucleotide-binding protein 1	9770345	Characterization of PKCI and comparative studies with FHIT, related members of the HIT protein family.

Q9R0Q1	SYTL4_MOUSE	Synaptotagmin-like protein 4	10497219	Novel rabphilin-3-like protein associates with insulin-containing granules in pancreatic beta cells.

P61019	RAB2A_HUMAN	Ras-related protein Rab-2A	16034420	Structural basis of family-wide Rab GTPase recognition by rabenosyn- 5.

P56589	PEX3_HUMAN	Peroxisomal biogenesis factor 3	10704444	PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis.

O59755	CUT12_SCHPO	Spindle pole body-associated protein cut12	12815070	Physical and functional interactions between polo kinase and the spindle pole component Cut12 regulate mitotic commitment in S. pombe.

Q9LZ76	PHYK1_ARATH	Phytol kinase 1, chloroplastic	16361393	The Arabidopsis vitamin E pathway gene5-1 mutant reveals a critical role for phytol kinase in seed tocopherol biosynthesis.

Q86XR7	TCAM2_HUMAN	TIR domain-containing adapter molecule 2	12721283	TIRP, a novel Toll/interleukin-1 receptor (TIR) domain-containing adapter protein involved in TIR signaling.

Q60670	SIK1_MOUSE	Serine/threonine-protein kinase SIK1	15177563	snf1lk encodes a protein kinase that may function in cell cycle regulation.

P48597	IF4E_XENLA	Eukaryotic translation initiation factor 4E	10635326	Maskin is a CPEB-associated factor that transiently interacts with eIF-4E.

Q93794	SEL10_CAEEL	F-box/WD repeat-containing protein sel-10	15306688	The Caenorhabditis elegans F-box protein SEL-10 promotes female development and may target FEM-1 and FEM-3 for degradation by the proteasome.

Q4X1A4	MTLD_ASPFU	Mannitol-1-phosphate 5-dehydrogenase	18452897	Characterization of recombinant Aspergillus fumigatus mannitol-1- phosphate 5-dehydrogenase and its application for the stereoselective synthesis of protio and deuterio forms of D-mannitol 1-phosphate.

P36104	SWD2_YEAST	COMPASS component SWD2	12819204	Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-ends.

Q01534	TSPY1_HUMAN	Testis-specific Y-encoded protein 1	8923009	Testis-specific protein, Y-encoded (TSPY) expression in testicular tissues.

Q91615	IRS1A_XENLA	Insulin receptor substrate 1-A	7791763	Molecular cloning of an amphibian insulin receptor substrate 1-like cDNA and involvement of phosphatidylinositol 3-kinase in insulin- induced Xenopus oocyte maturation.

P53083	MDM34_YEAST	Mitochondrial distribution and morphology protein 34	14981098	Mmm2p, a mitochondrial outer membrane protein required for yeast mitochondrial shape and maintenance of mtDNA nucleoids.

Q7XAK4	GID2_ORYSJ	F-box protein GID2	12649483	Accumulation of phosphorylated repressor for gibberellin signaling in an F-box mutant.

Q9XF04	CLV3_ARATH	Protein CLAVATA 3	16603652	Dynamic and compensatory responses of Arabidopsis shoot and floral meristems to CLV3 signaling.

P69852	HSK3_YEAST	DASH complex subunit HSK3	15632076	Genetic analysis of the kinetochore DASH complex reveals an antagonistic relationship with the ras/protein kinase A pathway and a novel subunit required for Ask1 association.

Q9VKK1	EDC4_DROME	Enhancer of mRNA-decapping protein 4 homolog	17901217	Target-specific requirements for enhancers of decapping in miRNA- mediated gene silencing.

P15330	DORS_DROME	Embryonic polarity protein dorsal	12653959	Tamo selectively modulates nuclear import in Drosophila.

Q9UUM7	HOB3_SCHPO	Protein hob3	11274158	Human BIN3 complements the F-actin localization defects caused by loss of Hob3p, the fission yeast homolog of Rvs161p.

Q8WXG9	GPR98_HUMAN	G-protein coupled receptor 98	14740321	Mutations in the VLGR1 gene implicate G-protein signaling in the pathogenesis of Usher syndrome type II.

P58957	G39AB_DROME	Putative gustatory receptor 39a, isoform C	10710312	Candidate taste receptors in Drosophila.

O14040	DIS3L_SCHPO	Dis3-like exonuclease C2C4.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O95619	YETS4_HUMAN	YEATS domain-containing protein 4	14966270	Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans.

P00128	QCR7_YEAST	Cytochrome b-c1 complex subunit 7	10873857	Structure at 2.3 A resolution of the cytochrome bc1 complex from the yeast Saccharomyces cerevisiae co-crystallized with an antibody Fv fragment.

Q9UHV8	PP13_HUMAN	Galactoside-binding soluble lectin 13	10527825	Isolation and sequence analysis of a cDNA encoding human placental tissue protein 13 (PP13), a new lysophospholipase, homologue of human eosinophil Charcot-Leyden crystal protein.

Q04116	YHP1_YEAST	Homeobox protein YHP1	10705372	YHP1 encodes a new homeoprotein that binds to the IME1 promoter in Saccharomyces cerevisiae.

P57723	PCBP4_HUMAN	Poly(rC)-binding protein 4	10936052	Identification of two novel mammalian genes establishes a subfamily of KH-domain RNA-binding proteins.

P22607	FGFR3_HUMAN	Fibroblast growth factor receptor 3	14732692	Insights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuity.

Q8WVN8	UB2Q2_HUMAN	Ubiquitin-conjugating enzyme E2 Q2	20061386	The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.

O75600	KBL_HUMAN	2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial	10712613	Molecular cloning of the human and murine 2-amino-3-ketobutyrate coenzyme A ligase cDNAs.

P23467	PTPRB_HUMAN	Receptor-type tyrosine-protein phosphatase beta	19116766	Tyrosine phosphatase beta regulates angiopoietin-Tie2 signaling in human endothelial cells.

Q9JI60	LRAT_MOUSE	Lecithin retinol acyltransferase	11108736	Lecithin:retinol acyltransferase from mouse and rat liver. cDNA cloning and liver-specific regulation by dietary vitamin A and retinoic acid.

P38794	PCL5_YEAST	PHO85 cyclin-5	12101234	Regulation of the transcription factor Gcn4 by Pho85 cyclin PCL5.

Q13342	LY10_HUMAN	Nuclear body protein SP140	8695863	LYSP100-associated nuclear domains (LANDs): description of a new class of subnuclear structures and their relationship to PML nuclear bodies.

Q9Y4C5	CHST2_HUMAN	Carbohydrate sulfotransferase 2	12855678	Golgi localization of carbohydrate sulfotransferases is a determinant of L-selectin ligand biosynthesis.

P83246	GST_ASADI	Glutathione S-transferase	12139969	Purification and characterization of a novel glutathione S- transferase from Asaphis dichotoma.

Q9LX99	GRIMP_ARATH	Geminivirus Rep-interacting motor protein	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q96GC6	ZN274_HUMAN	Zinc finger protein 274	10520746	Computer sequence analysis of human highly conserved zinc finger modules.

Q09969	BNIP3_CAEEL	NIP3 homolog	11114722	The C. elegans orthologue ceBNIP3 interacts with CED-9 and CED-3 but kills through a BH3- and caspase-independent mechanism.

P40319	ELO3_YEAST	Elongation of fatty acids protein 3	9832547	Involvement of long chain fatty acid elongation in the trafficking of secretory vesicles in yeast.

Q8CGX0	IF2B1_RAT	Insulin-like growth factor 2 mRNA-binding protein 1	14614102	Localization of a beta-actin messenger ribonucleoprotein complex with zipcode-binding protein modulates the density of dendritic filopodia and filopodial synapses.

Q564A5	HLYS2_CHLVR	Hydralysin-2	15824108	Hydralysins, a new category of beta-pore-forming toxins in cnidaria.

O43009	MU110_SCHPO	Meiotically up-regulated gene 110 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NWZ5	UCKL1_HUMAN	Uridine-cytidine kinase-like 1	16709802	NK lytic-associated molecule, involved in NK cytotoxic function, is an E3 ligase.

O42854	YFHH_SCHPO	SH3 domain-containing protein C23A1.17	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q93352	HM36_CAEEL	Homeobox protein ceh-36	15095973	The C. elegans ceh-36 gene encodes a putative homeodomain transcription factor involved in chemosensory functions of ASE and AWC neurons.

Q9NUX5	POTE1_HUMAN	Protection of telomeres protein 1	12768206	POT1 as a terminal transducer of TRF1 telomere length control.

O94560	YGD1_SCHPO	Uncharacterized WD repeat-containing protein C1773.01	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O49213	FCL1_ARATH	GDP-L-fucose synthase 1	10758496	A bifunctional epimerase-reductase acts downstream of the MUR1 gene product and completes the de novo synthesis of GDP-L-fucose in Arabidopsis.

Q80T23	SYTL5_MOUSE	Synaptotagmin-like protein 5	12590134	Slp4-a/granuphilin-a inhibits dense-core vesicle exocytosis through interaction with the GDP-bound form of Rab27A in PC12 cells.

P48763	SL9A2_RAT	Sodium/hydrogen exchanger 2	7683411	Molecular cloning, sequencing, tissue distribution, and functional expression of a Na+/H+ exchanger (NHE-2).

Q9Y463	DYR1B_HUMAN	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	9918863	Cloning and characterization of DYRK1B, a novel member of the DYRK family of protein kinases.

Q09428	ABCC8_HUMAN	ATP-binding cassette sub-family C member 8	7716548	Mutations in the sulfonylurea receptor gene in familial persistent hyperinsulinemic hypoglycemia of infancy.

Q960X4	TIP60_DROME	Histone acetyltransferase Tip60	15528408	Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions.

P92979	APR1_ARATH	5'-adenylylsulfate reductase 1, chloroplastic	8917600	Sulfate reduction in higher plants: molecular evidence for a novel 5'-adenylylsulfate reductase.

Q9C5Q2	AI5L3_ARATH	ABSCISIC ACID-INSENSITIVE 5-like protein 3	12084834	The homologous ABI5 and EEL transcription factors function antagonistically to fine-tune gene expression during late embryogenesis.

Q7KQZ4	LOLA3_DROME	Longitudinals lacking protein, isoforms A/B/D/L	11880341	Lola regulates midline crossing of CNS axons in Drosophila.

O75900	MMP23_HUMAN	Matrix metalloproteinase-23	9740677	Isolation and characterization of two novel metalloproteinase genes linked to the Cdc2L locus on human chromosome 1p36.3.

P02538	K2C6A_HUMAN	Keratin, type II cytoskeletal 6A	15731013	Identification of trichoplein, a novel keratin filament-binding protein.

P53169	YBP2_YEAST	YAP1-binding protein 2	14562095	Global analysis of protein localization in budding yeast.

O75369	FLNB_HUMAN	Filamin-B	12393796	Filamin A and filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact.

P49711	CTCF_HUMAN	Transcriptional repressor CTCF	8649389	An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes.

P68404	KPCB_MOUSE	Protein kinase C beta type	12118249	PKC-beta controls I kappa B kinase lipid raft recruitment and activation in response to BCR signaling.

O32504	PPRA_DEIRA	DNA repair protein pprA	15458422	PprA: a novel protein from Deinococcus radiodurans that stimulates DNA ligation.

Q9W358	RIC8_DROME	Synembryn	16228010	Drosophila Ric-8 regulates Galphai cortical localization to promote Galphai-dependent planar orientation of the mitotic spindle during asymmetric cell division.

Q9Z336	DYLT1_RAT	Dynein light chain Tctex-type 1	12591166	Sensory neuron proteins interact with the intracellular domains of sodium channel NaV1.8.

O94235	MPH1_SCHPO	Serine/threonine-protein kinase mph1	9601094	Mph1, a member of the Mps1-like family of dual specificity protein kinases, is required for the spindle checkpoint in S. pombe.

Q63468	KPRA_RAT	Phosphoribosyl pyrophosphate synthase-associated protein 1	8132556	A novel 39-kDa phosphoribosylpyrophosphate synthetase-associated protein of rat liver. Cloning, high sequence similarity to the catalytic subunits, and a negative regulatory role.

P39928	SLN1_YEAST	Osmosensing histidine protein kinase SLN1	14656441	The yeast YPD1/SLN1 complex: insights into molecular recognition in two-component signaling systems.

O76463	NFT1_CAEEL	Nitrilase and fragile histidine triad fusion protein NitFhit	9671749	Nitrilase and Fhit homologs are encoded as fusion proteins in Drosophila melanogaster and Caenorhabditis elegans.

Q8K339	KIN17_MOUSE	DNA/RNA-binding protein KIN17	8954809	Molecular cloning and characterization of the mouse Kin17 gene coding for a Zn-finger protein that preferentially recognizes bent DNA.

Q8R1P4	ATG10_MOUSE	Ubiquitin-like-conjugating enzyme ATG10	12890687	The mouse APG10 homologue, an E2-like enzyme for Apg12p conjugation, facilitates MAP-LC3 modification.

P40958	MAD2_YEAST	Mitotic spindle checkpoint component MAD2	11726501	Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores.

O75449	KTNA1_HUMAN	Katanin p60 ATPase-containing subunit A1	10751153	Two domains of p80 katanin regulate microtubule severing and spindle pole targeting by p60 katanin.

O54790	MAFG_MOUSE	Transcription factor MafG	9679061	Impaired megakaryopoiesis and behavioral defects in mafG-null mutant mice.

Q99607	ELF4_HUMAN	ETS-related transcription factor Elf-4	9524226	Cloning of a novel human ELF-1-related ETS transcription factor, ELFR, its characterization and chromosomal assignment relative to ELF- 1.

P24309	DBR1_YEAST	Lariat debranching enzyme	1850323	Isolation and characterization of the gene encoding yeast debranching enzyme.

Q9QXY2	SRCN1_RAT	SRC kinase signaling inhibitor 1	18662323	Characterization of a multidomain adaptor protein, p140Cap, as part of a pre-synaptic complex.

P80162	CXCL6_HUMAN	C-X-C motif chemokine 6	8399143	Human and bovine granulocyte chemotactic protein-2: complete amino acid sequence and functional characterization as chemokines.

Q9FQ03	XRN3_ARATH	5'-3' exoribonuclease 3	11106401	Novel features of the XRN-family in Arabidopsis: evidence that AtXRN4, one of several orthologs of nuclear Xrn2p/Rat1p, functions in the cytoplasm.

Q84JU4	IBR5_ARATH	Protein-tyrosine-phosphatase IBR5	19000167	Arabidopsis mitogen-activated protein kinase MPK12 interacts with the MAPK phosphatase IBR5 and regulates auxin signaling.

Q9W4E2	NBEA_DROME	Neurobeachin	12072466	rugose (rg), a Drosophila A kinase anchor protein, is required for retinal pattern formation and interacts genetically with multiple signaling pathways.

P34163	TGL1_YEAST	Sterol esterase TGL1	15713625	The Saccharomyces cerevisiae YLL012/YEH1, YLR020/YEH2, and TGL1 genes encode a novel family of membrane-anchored lipases that are required for steryl ester hydrolysis.

P50278	SOL1_YEAST	6-phosphogluconolactonase-like protein 1	14562095	Global analysis of protein localization in budding yeast.

Q9BRQ8	AIFM2_HUMAN	Apoptosis-inducing factor 2	15958387	The human apoptosis-inducing protein AMID is an oxidoreductase with a modified flavin cofactor and DNA binding activity.

Q8IYW5	RN168_HUMAN	E3 ubiquitin-protein ligase RNF168	19203578	The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage.

O14492	SH2B2_HUMAN	SH2B adapter protein 2	9233773	Cloning and characterization of APS, an adaptor molecule containing PH and SH2 domains that is tyrosine phosphorylated upon B-cell receptor stimulation.

Q20751	IF5A2_CAEEL	Eukaryotic translation initiation factor 5A-2	15003625	The Caenorhabditis elegans eukaryotic initiation factor 5A homologue, IFF-1, is required for germ cell proliferation, gametogenesis and localization of the P-granule component PGL-1.

O09130	NF2IP_MOUSE	NFATC2-interacting protein	8943202	NF-AT-driven interleukin-4 transcription potentiated by NIP45.

Q9SXJ6	CLPP3_ARATH	ATP-dependent Clp protease proteolytic subunit 3, chloroplastic	14593120	Clp protease complexes from photosynthetic and non-photosynthetic plastids and mitochondria of plants, their predicted three-dimensional structures, and functional implications.

Q7TQB8	T2R40_MOUSE	Taste receptor type 2 member 40	12734386	Evolutionary relationships of the Tas2r receptor gene families in mouse and human.

P53187	HOP2_YEAST	Homologous-pairing protein 2	15249670	Heterodimeric complexes of Hop2 and Mnd1 function with Dmc1 to promote meiotic homolog juxtaposition and strand assimilation.

Q9VS24	MELT_DROME	Protein melted	11102367	Mutations affecting the development of the peripheral nervous system in Drosophila: a molecular screen for novel proteins.

Q03322	TLG1_YEAST	T-SNARE affecting a late Golgi compartment protein 1	10397773	A role for Tlg1p in the transport of proteins within the Golgi apparatus of Saccharomyces cerevisiae.

Q9NHC3	CED2_CAEEL	Cell death abnormality protein 2	11449278	Phagocytosis promotes programmed cell death in C. elegans.

Q9USV1	SFR1_SCHPO	Swi5-dependent recombination DNA repair protein 1	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

Q9UNI6	DUS12_HUMAN	Dual specificity protein phosphatase 12	10446167	Identification of the human YVH1 protein-tyrosine phosphatase orthologue reveals a novel zinc binding domain essential for in vivo function.

O42601	S17B1_XENLA	Transcription factor Sox-17-beta.1	15302595	Repression of nodal expression by maternal B1-type SOXs regulates germ layer formation in Xenopus and zebrafish.

P32561	RPD3_YEAST	Histone deacetylase RPD3	15143171	The Rpd3-Sin3 histone deacetylase regulates replication timing and enables intra-S origin control in Saccharomyces cerevisiae.

P23739	SUIS_RAT	Sucrase-isomaltase, intestinal	6802834	Biosynthesis of sucrase-isomaltase. Purification and NH2-terminal amino acid sequence of the rat sucrase-isomaltase precursor (pro- sucrase-isomaltase) from fetal intestinal transplants.

O75191	XYLB_HUMAN	Xylulose kinase	9763671	Genomic structure of a novel human gene (XYLB) on chromosome 3p22-->p21.3 encoding a xylulokinase-like protein.

P29459	IL12A_HUMAN	Interleukin-12 subunit alpha	1674604	Coexpression of two distinct genes is required to generate secreted bioactive cytotoxic lymphocyte maturation factor.

P53104	ATG1_YEAST	Serine/threonine-protein kinase ATG1	11309418	Cvt9/Gsa9 functions in sequestering selective cytosolic cargo destined for the vacuole.

Q07092	COGA1_HUMAN	Collagen alpha-1(XVI) chain	1284248	Molecular cloning and partial characterization of a novel collagen chain, alpha 1(XVI), consisting of repetitive collagenous domains and cysteine-containing non-collagenous segments.

Q9C7G0	MA658_ARATH	65-kDa microtubule-associated protein 8	15469496	Molecular dissection of plant cytokinesis and phragmoplast structure: a survey of GFP-tagged proteins.

Q810H6	DISC1_RAT	Disrupted in schizophrenia 1 homolog	17035248	DISC1-NDEL1/NUDEL protein interaction, an essential component for neurite outgrowth, is modulated by genetic variations of DISC1.

Q99990	VGLL1_HUMAN	Transcription cofactor vestigial-like protein 1	10518497	TONDU (TDU), a novel human protein related to the product of vestigial (vg) gene of Drosophila melanogaster interacts with vertebrate TEF factors and substitutes for Vg function in wing formation.

P49025	CTRO_MOUSE	Citron Rho-interacting kinase	8543060	A novel partner for the GTP-bound forms of rho and rac.

Q94A06	M2K1_ARATH	Mitogen-activated protein kinase kinase 1	15225555	The MKK2 pathway mediates cold and salt stress signaling in Arabidopsis.

O74889	SAC31_SCHPO	SAC3 family protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P07713	DECA_DROME	Protein decapentaplegic	11136982	Gradient formation of the TGF-beta homolog Dpp.

Q10136	STE7_SCHPO	Protein ste7	10835379	Schizosaccharomyces pombe Ste7p is required for both promotion and withholding of the entry to meiosis.

Q06630	MHR1_YEAST	Mitochondrial homologous recombination protein 1	12198175	Recombination-dependent mtDNA partitioning: in vivo role of Mhr1p to promote pairing of homologous DNA.

Q9BYM8	UB7I3_HUMAN	RanBP-type and C3HC4-type zinc finger-containing protein 1	19136968	Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation.

P0AC41	DHSA_ECOLI	Succinate dehydrogenase flavoprotein subunit	12560550	Architecture of succinate dehydrogenase and reactive oxygen species generation.

P06213	INSR_HUMAN	Insulin receptor	7559478	Distinct modes of interaction of SHC and insulin receptor substrate-1 with the insulin receptor NPEY region via non-SH2 domains.

Q15072	OZF_HUMAN	Zinc finger protein OZF	8107129	The OZF gene encodes a protein consisting essentially of zinc finger motifs.

Q96L73	NSD1_HUMAN	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific	11509567	Identification and characterization of a novel androgen receptor coregulator ARA267-alpha in prostate cancer cells.

Q62994	FUT4_RAT	Alpha-(1,3)-fucosyltransferase	9111142	Cloning of a rat alpha1,3-fucosyltransferase gene: a member of the fucosyltransferase IV family.

P46309	GSH1_ARATH	Glutamate--cysteine ligase, chloroplastic	7770518	A cadmium-sensitive, glutathione-deficient mutant of Arabidopsis thaliana.

P07713	DECA_DROME	Protein decapentaplegic	7700357	Induction of visceral and cardiac mesoderm by ectodermal Dpp in the early Drosophila embryo.

Q9DED4	CIRBB_XENLA	Cold-inducible RNA-binding protein B	18687117	Cold-inducible RNA binding protein (CIRP), a novel XTcf-3 specific target gene regulates neural development in Xenopus.

P83473	OSTCN_HALDD	Osteocalcin	14668966	Characterization of osteocalcin (BGP) and matrix Gla protein (MGP) fish specific antibodies: validation for immunodetection studies in lower vertebrates.

Q9JM14	NT5C_MOUSE	5'(3')-deoxyribonucleotidase, cytosolic type	10681516	Mammalian 5'(3')-deoxyribonucleotidase, cDNA cloning, and overexpression of the enzyme in Escherichia coli and mammalian cells.

P0CB42	ALKB1_MOUSE	Alkylated DNA repair protein alkB homolog 1	18163532	Impaired placental trophoblast lineage differentiation in Alkbh1(-/-) mice.

P54114	ALDH3_YEAST	Aldehyde dehydrogenase [NAD(P)+] 2	10407263	A proposal for nomenclature of aldehyde dehydrogenases in Saccharomyces cerevisiae and characterization of the stress-inducible ALD2 and ALD3 genes.

Q64623	DUS1_RAT	Dual specificity protein phosphatase 1	11423551	MAP kinase phosphatase-1 gene transcription in rat neuroendocrine cells is modulated by a calcium-sensitive block to elongation in the first exon.

P40464	FLX1_YEAST	Mitochondrial FAD carrier protein FLX1	8631763	FLX1 codes for a carrier protein involved in maintaining a proper balance of flavin nucleotides in yeast mitochondria.

Q9ESG3	TMM27_RAT	Collectrin	11278314	Collectrin, a collecting duct-specific transmembrane glycoprotein, is a novel homolog of ACE2 and is developmentally regulated in embryonic kidneys.

Q9UBS0	KS6B2_HUMAN	Ribosomal protein S6 kinase beta-2	9878560	Cloning and characterization of p70 S6Kbeta defines a novel family of p70 S6 kinases.

Q9M9V6	ICS2_ARATH	Isochorismate synthase 2, chloroplastic	18451262	Characterization and biological function of the ISOCHORISMATE SYNTHASE2 gene of Arabidopsis.

O88188	LY86_MOUSE	Lymphocyte antigen 86	9686597	Mouse MD-1, a molecule that is physically associated with RP105 and positively regulates its expression.

Q6PTT0	ACY1B_RAT	Aminoacylase-1B	11012679	The rat kidney acylase I, characterization and molecular cloning. Differences with other acylases I.

Q9ULL4	PLXB3_HUMAN	Plexin-B3	15218527	Plexin-B3 is a functional receptor for semaphorin 5A.

P84285	ARE2_CANAL	Sterol O-acyltransferase 2	15184069	Molecular cloning and biochemical characterization of Candida albicans acyl-CoA:sterol acyltransferase, a potential target of antifungal agents.

Q8CHJ2	AQP12_MOUSE	Aquaporin-12	15809071	Identification of a novel aquaporin, AQP12, expressed in pancreatic acinar cells.

P32383	PLC1_YEAST	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase 1	8395015	Genetic and biochemical characterization of a phosphatidylinositol- specific phospholipase C in Saccharomyces cerevisiae.

O75762	TRPA1_HUMAN	Transient receptor potential cation channel subfamily A member 1	10066796	An ankyrin-like protein with transmembrane domains is specifically lost after oncogenic transformation of human fibroblasts.

P53698	CYC_CANAL	Cytochrome c	9271112	Phylogenetic relationships of fungal cytochromes c.

P53844	PDR17_YEAST	Phosphatidylinositol transfer protein PDR17	10848624	Identification of a novel family of nonclassic yeast phosphatidylinositol transfer proteins whose function modulates phospholipase D activity and Sec14p-independent cell growth.

Q14119	VEZF1_HUMAN	Vascular endothelial zinc finger 1	8035792	Molecular cloning of a novel human cDNA encoding a zinc finger protein that binds to the interleukin-3 promoter.

Q9NQ76	MEPE_HUMAN	Matrix extracellular phosphoglycoprotein	10945470	MEPE, a new gene expressed in bone marrow and tumors causing osteomalacia.

Q38997	KIN10_ARATH	SNF1-related protein kinase catalytic subunit alpha KIN10	18931139	Interaction of the WD40 domain of a myoinositol polyphosphate 5- phosphatase with SnRK1 links inositol, sugar, and stress signaling.

Q6UX65	DRAM2_HUMAN	DNA damage-regulated autophagy modulator protein 2	19556885	Analysis of DRAM-related proteins reveals evolutionarily conserved and divergent roles in the control of autophagy.

P69210	MDTI_ECOLI	Spermidine export protein mdtI	18039771	Identification of a spermidine excretion protein complex (MdtJI) in Escherichia coli.

P28285	5HT2A_DROME	5-hydroxytryptamine receptor 2A	1310937	A family of Drosophila serotonin receptors with distinct intracellular signalling properties and expression patterns.

O94817	ATG12_HUMAN	Ubiquitin-like protein ATG12	9852036	A new protein conjugation system in human. The counterpart of the yeast Apg12p conjugation system essential for autophagy.

Q8TGN9	NAG1_YEAST	Protein NAG1	18310357	Unconventional genomic architecture in the budding yeast Saccharomyces cerevisiae masks the nested antisense gene NAG1.

P30730	LSHR_MOUSE	Lutropin-choriogonadotropic hormone receptor	1311310	Evidence for dual coupling of the murine luteinizing hormone receptor to adenylyl cyclase and phosphoinositide breakdown and Ca2+ mobilization. Studies with the cloned murine luteinizing hormone receptor expressed in L cells.

Q08273	RBX1_YEAST	RING-box protein HRT1	10385629	Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34.

Q9Y709	SKP1_SCHPO	Suppressor of kinetochore protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q14451	GRB7_HUMAN	Growth factor receptor-bound protein 7	10664463	Interaction of the Grb7 adapter protein with Rnd1, a new member of the Rho family.

P21583	SCF_HUMAN	Kit ligand	10884405	Crystal structure of human stem cell factor: implication for stem cell factor receptor dimerization and activation.

P50219	MNX1_HUMAN	Motor neuron and pancreas homeobox protein 1	7914194	A novel human homeobox gene distantly related to proboscipedia is expressed in lymphoid and pancreatic tissues.

Q8IZT8	HS3S5_HUMAN	Heparan sulfate glucosamine 3-O-sulfotransferase 5	12138164	Heparan sulfate 3-O-sulfotransferase isoform 5 generates both an antithrombin-binding site and an entry receptor for herpes simplex virus, type 1.

P46013	KI67_HUMAN	Antigen KI-67	11342549	A novel nucleolar protein, NIFK, interacts with the forkhead associated domain of Ki-67 antigen in mitosis.

P61962	DCAF7_HUMAN	DDB1- and CUL4-associated factor 7	14593110	Phosphorylation of Ser640 in muscle glycogen synthase by DYRK family protein kinases.

P04451	RL23_YEAST	60S ribosomal protein L23	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q23989	QUAI_DROME	Villin-like protein quail	8044841	The villin-like protein encoded by the Drosophila quail gene is required for actin bundle assembly during oogenesis.

P40567	MSL1_YEAST	U2 small nuclear ribonucleoprotein B''	9799242	The yeast U2A'/U2B complex is required for pre-spliceosome formation.

Q13617	CUL2_HUMAN	Cullin-2	8681378	cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family.

Q13425	SNTB2_HUMAN	Beta-2-syntrophin	8576247	The three human syntrophin genes are expressed in diverse tissues, have distinct chromosomal locations, and each bind to dystrophin and its relatives.

Q9NQB0	TF7L2_HUMAN	Transcription factor 7-like 2	17873903	Coiled-coil domain containing 85B suppresses the beta-catenin activity in a p53-dependent manner.

P56539	CAV3_HUMAN	Caveolin-3	17275750	Novel mechanism for sudden infant death syndrome: persistent late sodium current secondary to mutations in caveolin-3.

Q60592	MAST2_MOUSE	Microtubule-associated serine/threonine-protein kinase 2	8902215	Increased activity associated with the MAST205 protein kinase complex during mammalian spermiogenesis.

Q54N00	FORH_DICDI	Formin-H	15908944	The Diaphanous-related formin dDia2 is required for the formation and maintenance of filopodia.

P34164	SIP2_YEAST	SNF1 protein kinase subunit beta-2	7813428	A family of proteins containing a conserved domain that mediates interaction with the yeast SNF1 protein kinase complex.

Q9VJE5	CL190_DROME	Restin homolog	11076973	Lava lamp, a novel peripheral Golgi protein, is required for Drosophila melanogaster cellularization.

Q8L5Y6	CAND1_ARATH	Cullin-associated NEDD8-dissociated protein 1	16844902	Arabidopsis CULLIN4 forms an E3 ubiquitin ligase with RBX1 and the CDD complex in mediating light control of development.

Q62726	ICK_RAT	Serine/threonine-protein kinase ICK	8570168	Molecular cloning of a novel serine/threonine kinase, MRK, possibly involved in cardiac development.

P22803	TRX2_YEAST	Thioredoxin-2	11169096	Role of the glutathione/glutaredoxin and thioredoxin systems in yeast growth and response to stress conditions.

P29377	S100G_HUMAN	Protein S100-G	1610358	Molecular cloning and chromosomal assignment of human calbindin- D9k.

O95059	RPP14_HUMAN	Ribonuclease P protein subunit p14	10024167	Rpp14 and Rpp29, two protein subunits of human ribonuclease P.

Q9P7H3	PHB1_SCHPO	Prohibitin-1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8BPP1	MB212_MOUSE	Protein mab-21-like 2	15385160	Requirement for Mab21l2 during development of murine retina and ventral body wall.

Q39255	SKP1A_ARATH	SKP1-like protein 1A	18948957	Control of plant germline proliferation by SCF(FBL17) degradation of cell cycle inhibitors.

O94547	SRK1_SCHPO	Serine/threonine-protein kinase srk1	12589433	Mkp1 and Mkp2, two MAPKAP-kinase homologues in Schizosaccharomyces pombe, interact with the MAP kinase Sty1.

O88470	FOXL2_MOUSE	Forkhead box protein L2	20005806	Somatic sex reprogramming of adult ovaries to testes by FOXL2 ablation.

Q96J87	CELF6_HUMAN	CUGBP Elav-like family member 6	14761971	CELF6, a member of the CELF family of RNA-binding proteins, regulates muscle-specific splicing enhancer-dependent alternative splicing.

P28288	ABCD3_HUMAN	ATP-binding cassette sub-family D member 3	9521874	Genomic organization of the 70-kDa peroxisomal membrane protein gene (PXMP1).

P48731	ATH1_ARATH	Homeobox protein ATH1	17908157	The Arabidopsis TALE homeobox gene ATH1 controls floral competency through positive regulation of FLC.

P91443	HUM6_CAEEL	Unconventional myosin heavy chain 6	9325109	A family of unconventional myosins from the nematode Caenorhabditis elegans.

Q3EDL4	Y1154_ARATH	Probable serine/threonine-protein kinase At1g01540	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q1RKN3	TLH2_SCHPO	ATP-dependent DNA helicase tlh2	15591066	Expression of a RecQ helicase homolog affects progression through crisis in fission yeast lacking telomerase.

O14014	RGA3_SCHPO	Probable Rho-type GTPase-activating protein 3	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

Q12680	GLT1_YEAST	Glutamate synthase [NADH]	7836314	Saccharomyces cerevisiae has a single glutamate synthase gene coding for a plant-like high-molecular-weight polypeptide.

Q94A28	ACO3M_ARATH	Aconitate hydratase 3, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P53163	MNP1_YEAST	54S ribosomal protein L12, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P50572	GBRR1_RAT	Gamma-aminobutyric acid receptor subunit rho-1	12431995	ZIP3, a new splice variant of the PKC-zeta-interacting protein family, binds to GABAC receptors, PKC-zeta, and Kv beta 2.

Q9QZD9	EIF3I_MOUSE	Eukaryotic translation initiation factor 3 subunit I	17581632	Reconstitution reveals the functional core of mammalian eIF3.

Q9CQ75	NDUA2_MOUSE	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2	10318868	Up-regulation of nuclear and mitochondrial genes in the skeletal muscle of mice lacking the heart/muscle isoform of the adenine nucleotide translocator.

Q9ER74	SALL1_MOUSE	Sal-like protein 1	11688560	Murine homolog of SALL1 is essential for ureteric bud invasion in kidney development.

O59755	CUT12_SCHPO	Spindle pole body-associated protein cut12	9531532	The fission yeast SPB component Cut12 links bipolar spindle formation to mitotic control.

P45975	SUV39_DROME	Histone-lysine N-methyltransferase Su(var)3-9	11571273	Physical and functional association of SU(VAR)3-9 and HDAC1 in Drosophila.

P48581	RAD17_YEAST	DNA damage checkpoint control protein RAD17	12604797	Yeast Rad17/Mec3/Ddc1: a sliding clamp for the DNA damage checkpoint.

Q9VA00	ZWILC_DROME	Protein zwilch	12686595	Zwilch, a new component of the ZW10/ROD complex required for kinetochore functions.

Q96QD8	S38A2_HUMAN	Sodium-coupled neutral amino acid transporter 2	10930503	Primary structure, functional characteristics and tissue expression pattern of human ATA2, a subtype of amino acid transport system A.

P29972	AQP1_HUMAN	Aquaporin-1	1722319	Isolation of the cDNA for erythrocyte integral membrane protein of 28 kilodaltons: member of an ancient channel family.

P41516	TOP2A_RAT	DNA topoisomerase 2-alpha	8390253	Nucleotide sequence analysis of the cDNA for rat DNA topoisomerase II.

O76329	ACTNB_DICDI	Interaptin	10704840	Severe developmental defects in Dictyostelium null mutants for actin- binding proteins.

Q9UKL4	CXD2_HUMAN	Gap junction delta-2 protein	10462698	Structure, chromosomal localization, and brain expression of human Cx36 gene.

P35372	OPRM_HUMAN	Mu-type opioid receptor	7905839	Human mu opiate receptor. cDNA and genomic clones, pharmacologic characterization and chromosomal assignment.

Q54NW4	LIMB_DICDI	LIM domain-containing protein B	10749929	The Dictyostelium LIM domain-containing protein LIM2 is essential for proper chemotaxis and morphogenesis.

O42918	AMY4_SCHPO	Alpha-amylase 4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q03373	DIG2_YEAST	Down-regulator of invasive growth 2	8918885	Two novel targets of the MAP kinase Kss1 are negative regulators of invasive growth in the yeast Saccharomyces cerevisiae.

Q0WRB9	PUP8_ARATH	Probable purine permease 8	10662864	A new family of high-affinity transporters for adenine, cytosine, and purine derivatives in Arabidopsis.

Q92547	TOPB1_HUMAN	DNA topoisomerase 2-binding protein 1	12773567	PML colocalizes with and stabilizes the DNA damage response protein TopBP1.

P39940	RSP5_YEAST	E3 ubiquitin-protein ligase RSP5	12163175	PY motifs of Rod1 are required for binding to Rsp5 and for drug resistance.

O74648	IAH1_SCHPO	Isoamyl acetate-hydrolyzing esterase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O80536	PIF3_ARATH	Transcription factor PIF3	12826627	A link between circadian-controlled bHLH factors and the APRR1/TOC1 quintet in Arabidopsis thaliana.

P84213	BOMB_BOMVA	Bombesin	4537042	Isolation and amino acid sequences of alytesin and bombesin, two analogous active tetradecapeptides from the skin of European discoglossid frogs.

Q9P7D1	YOFI_SCHPO	Uncharacterized protein P4H10.18c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P43609	RSC8_YEAST	Chromatin structure-remodeling complex protein RSC8	10329629	Transcriptional repression of the yeast CHA1 gene requires the chromatin-remodeling complex RSC.

Q4LBB9	OCTB2_DROME	Octopamine receptor beta-2R	15998303	Identification and characterization of a novel family of Drosophila beta-adrenergic-like octopamine G-protein coupled receptors.

P11240	COX5A_RAT	Cytochrome c oxidase subunit 5A, mitochondrial	7601105	Cytochrome-c oxidase in developing rat heart. Enzymic properties and amino-terminal sequences suggest identity of the fetal heart and the adult liver isoform.

Q9XWD6	CED1_CAEEL	Cell death abnormality protein 1	16740477	C. elegans Dynamin mediates the signaling of phagocytic receptor CED- 1 for the engulfment and degradation of apoptotic cells.

P41034	TTPA_RAT	Alpha-tocopherol transfer protein	8349655	Primary structure of alpha-tocopherol transfer protein from rat liver. Homology with cellular retinaldehyde-binding protein.

Q9R244	TRPC2_MOUSE	Short transient receptor potential channel 2	10051594	Mouse trp2, the homologue of the human trpc2 pseudogene, encodes mTrp2, a store depletion-activated capacitative Ca2+ entry channel.

Q13131	AAPK1_HUMAN	5'-AMP-activated protein kinase catalytic subunit alpha-1	18403135	Identification and characterization of a novel folliculin-interacting protein FNIP2.

Q9Y6D6	BIG1_HUMAN	Brefeldin A-inhibited guanine nucleotide-exchange protein 1	10212200	Purification and cloning of a brefeldin A-inhibited guanine nucleotide-exchange protein for ADP-ribosylation factors.

P50276	MUP1_YEAST	High-affinity methionine permease	8893857	The study of methionine uptake in Saccharomyces cerevisiae reveals a new family of amino acid permeases.

P40337	VHL_HUMAN	Von Hippel-Lindau disease tumor suppressor	12032852	The TRC8 hereditary kidney cancer gene suppresses growth and functions with VHL in a common pathway.

O00425	IF2B3_HUMAN	Insulin-like growth factor 2 mRNA-binding protein 3	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

P53817	PAG16_RAT	Group XVI phospholipase A2	8290259	Subtraction cloning of H-rev107, a gene specifically expressed in H- ras resistant fibroblasts.

O94326	YGK8_SCHPO	Zinc finger protein C725.08	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P43592	FAR7_YEAST	Factor arrest protein 7	12588993	Far3 and five interacting proteins prevent premature recovery from pheromone arrest in the budding yeast Saccharomyces cerevisiae.

Q13114	TRAF3_HUMAN	TNF receptor-associated factor 3	7533327	Involvement of CRAF1, a relative of TRAF, in CD40 signaling.

Q94A06	M2K1_ARATH	Mitogen-activated protein kinase kinase 1	10759527	ATMPK4, an Arabidopsis homolog of mitogen-activated protein kinase, is activated in vitro by AtMEK1 through threonine phosphorylation.

Q9WVE8	PACN2_MOUSE	Protein kinase C and casein kinase substrate in neurons protein 2	11082044	All three PACSIN isoforms bind to endocytic proteins and inhibit endocytosis.

P0ACS7	RPIR_ECOLI	HTH-type transcriptional regulator rpiR	8576032	Ribose catabolism of Escherichia coli: characterization of the rpiB gene encoding ribose phosphate isomerase B and of the rpiR gene, which is involved in regulation of rpiB expression.

Q10325	MST2_SCHPO	Histone acetyltransferase mst2	16199868	Schizosaccharomyces pombe mst2+ encodes a MYST family histone acetyltransferase that negatively regulates telomere silencing.

Q24522	BUN1_DROME	Protein bunched, class 1/class 3/D/E isoforms	9256356	The Drosophila bunched gene is a homologue of the growth factor stimulated mammalian TSC-22 sequence and is required during oogenesis.

C4AMC7	WASH3_HUMAN	Putative WAS protein family homolog 3	18159949	Human subtelomeric WASH genes encode a new subclass of the WASP family.

Q12309	CLF1_YEAST	Pre-mRNA-splicing factor CLF1	11842115	Functional and physical interactions between components of the Prp19p-associated complex.

Q9H0P0	5NT3_HUMAN	Cytosolic 5'-nucleotidase 3	8557639	Purification, microsequencing, and immunolocalization of p36, a new interferon-alpha-induced protein that is associated with human lupus inclusions.

Q01448	HPC2_YEAST	Histone promoter control protein 2	1406694	Identification of a new set of cell cycle-regulatory genes that regulate S-phase transcription of histone genes in Saccharomyces cerevisiae.

O94526	PTEN_SCHPO	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase ptn1	15249580	A novel phosphatidylinositol(3,4,5)P3 pathway in fission yeast.

Q9VZZ9	DOS_DROME	Protein daughter of sevenless	8681385	Dos, a novel PH domain containing protein required for signal transduction between Sevenless and Ras1 in Drosophila.

P10696	PPBN_HUMAN	Alkaline phosphatase, placental-like	2162249	Expression of a Nagao-type, phosphatidylinositol-glycan anchored alkaline phosphatase in human choriocarcinomas.

P04640	OSTCN_RAT	Osteocalcin	3265336	Characterization of the rat osteocalcin gene: stimulation of promoter activity by 1,25-dihydroxyvitamin D3.

O60493	SNX3_HUMAN	Sorting nexin-3	9819414	Identification of a family of sorting nexin molecules and characterization of their association with receptors.

Q9NRD1	FBX6_HUMAN	F-box only protein 6	10531035	Identification of a family of human F-box proteins.

O00268	TAF4_HUMAN	Transcription initiation factor TFIID subunit 4	8942982	Molecular cloning and analysis of two subunits of the human TFIID complex: hTAFII130 and hTAFII100.

Q9HAW4	CLSPN_HUMAN	Claspin	18662541	The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint.

P43606	PTR3_YEAST	SPS-sensor component PTR3	10409731	Ssy1p and Ptr3p are plasma membrane components of a yeast system that senses extracellular amino acids.

Q5HZG4	TAF3_MOUSE	Transcription initiation factor TFIID subunit 3	17704303	Switching of the core transcription machinery during myogenesis.

Q9Y271	CLTR1_HUMAN	Cysteinyl leukotriene receptor 1	10391245	Characterization of the human cysteinyl leukotriene CysLT1 receptor.

P11310	ACADM_HUMAN	Medium-chain specific acyl-CoA dehydrogenase, mitochondrial	2393404	Identification of a common mutation in patients with medium-chain acyl-CoA dehydrogenase deficiency.

Q8L5U0	CSN4_ARATH	COP9 signalosome complex subunit 4	10521526	Arabidopsis cop8 and fus4 mutations define the same gene that encodes subunit 4 of the COP9 signalosome.

P21524	RIR1_YEAST	Ribonucleoside-diphosphate reductase large chain 1	12732713	Subcellular localization of yeast ribonucleotide reductase regulated by the DNA replication and damage checkpoint pathways.

O43033	YGU4_SCHPO	Uncharacterized methyltransferase C3B9.04, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P52734	FGD1_MOUSE	FYVE, RhoGEF and PH domain-containing protein 1	12913069	Fgd1, the Cdc42 GEF responsible for faciogenital dysplasia, directly interacts with cortactin and mAbp1 to modulate cell shape.

Q43125	CRY1_ARATH	Cryptochrome-1	11752373	The signaling mechanism of Arabidopsis CRY1 involves direct interaction with COP1.

P32828	SLX5_YEAST	E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5	18032921	The yeast Slx5-Slx8 DNA integrity complex displays ubiquitin ligase activity.

Q91VE0	S27A4_MOUSE	Long-chain fatty acid transport protein 4	15653672	Enzymatic properties of purified murine fatty acid transport protein 4 and analysis of acyl-CoA synthetase activities in tissues from FATP4 null mice.

Q9LMX5	AFP2_ARATH	Ninja-family protein AFP2	18484180	A small plant-specific protein family of ABI five binding proteins (AFPs) regulates stress response in germinating Arabidopsis seeds and seedlings.

O77081	TPSTA_CAEEL	Protein-tyrosine sulfotransferase A	9733778	Molecular cloning and expression of human and mouse tyrosylprotein sulfotransferase-2 and a tyrosylprotein sulfotransferase homologue in Caenorhabditis elegans.

Q9NA13	IPLA_DICDI	Inositol 1,4,5-trisphosphate receptor-like protein A	18077554	The inositol 1,4,5-trisphosphate receptor is required to signal autophagic cell death.

P93835	DRE1B_ARATH	Dehydration-responsive element-binding protein 1B	9023378	Arabidopsis thaliana CBF1 encodes an AP2 domain-containing transcriptional activator that binds to the C-repeat/DRE, a cis-acting DNA regulatory element that stimulates transcription in response to low temperature and water deficit.

P11473	VDR_HUMAN	Vitamin D3 receptor	16252006	Ligand-induced transrepression by VDR through association of WSTF with acetylated histones.

O74452	SCW1_SCHPO	Cell wall integrity protein scw1	12242222	The Scw1 RNA-binding domain protein regulates septation and cell-wall structure in fission yeast.

Q8IX90	SKA3_HUMAN	Spindle and kinetochore-associated protein 3	19289083	The human kinetochore Ska1 complex facilitates microtubule depolymerization-coupled motility.

O00506	STK25_HUMAN	Serine/threonine-protein kinase 25	9160885	YSK1, a novel mammalian protein kinase structurally related to Ste20 and SPS1, but is not involved in the known MAPK pathways.

Q7M370	AAAD_RABIT	Arylacetamide deacetylase	9665742	Determination of lumenal orientation of microsomal 50-kDa esterase/N- deacetylase.

P38606	VATA_HUMAN	V-type proton ATPase catalytic subunit A	8463241	Identification of two subunit A isoforms of the vacuolar H(+)-ATPase in human osteoclastoma.

Q92794	MYST3_HUMAN	Histone acetyltransferase MYST3	11742995	Activation of AML1-mediated transcription by MOZ and inhibition by the MOZ-CBP fusion protein.

Q13487	SNPC2_HUMAN	snRNA-activating protein complex subunit 2	8524284	Cloning of two proximal sequence element-binding transcription factor subunits (gamma and delta) that are required for transcription of small nuclear RNA genes by RNA polymerases II and III and interact with the TATA-binding protein.

P42950	GSM1_YEAST	Glucose starvation modulator protein 1	15583838	Computationally analyzing the possible biological function of YJL103C--an ORF potentially involved in the regulation of energy process in yeast.

P38994	MSS4_YEAST	Probable phosphatidylinositol-4-phosphate 5-kinase MSS4	9624178	MSS4, a phosphatidylinositol-4-phosphate 5-kinase required for organization of the actin cytoskeleton in Saccharomyces cerevisiae.

P34096	RNAS4_HUMAN	Ribonuclease 4	7742370	Molecular cloning and expression of human ribonuclease 4 cDNA.

Q8I6R7	ACN2_ACAGO	Acanthoscurrin-2	12818635	Acanthoscurrin: a novel glycine-rich antimicrobial peptide constitutively expressed in the hemocytes of the spider Acanthoscurria gomesiana.

Q09825	SAD1_SCHPO	Spindle pole body-associated protein sad1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O35613	DAXX_MOUSE	Death domain-associated protein 6	9215629	Daxx, a novel Fas-binding protein that activates JNK and apoptosis.

Q99J83	ATG5_MOUSE	Autophagy protein 5	11266458	Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells.

Q9BXH1	BBC3_HUMAN	Bcl-2-binding component 3	11463391	PUMA induces the rapid apoptosis of colorectal cancer cells.

O35152	BET1L_RAT	BET1-like protein	9242691	GS15, a 15-kilodalton Golgi soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) homologous to rbet1.

Q13309	SKP2_HUMAN	S-phase kinase-associated protein 2	16880511	Regulation of p27 degradation and S-phase progression by Ro52 RING finger protein.

Q19MC2	SCRA_ARAHA	Defensin-like protein A	20400945	Evolution of self-compatibility in Arabidopsis by a mutation in the male specificity gene.

Q23121	RSP1_CAEEL	Probable splicing factor, arginine/serine-rich 1	10906451	Unique and redundant functions of SR proteins, a conserved family of splicing factors, in Caenorhabditis elegans development.

O95721	SNP29_HUMAN	Synaptosomal-associated protein 29	9852078	Three novel proteins of the syntaxin/SNAP-25 family.

P75954	YCFS_ECOLI	Probable L,D-transpeptidase YcfS	18456808	Identification of the L,D-transpeptidases for peptidoglycan cross- linking in Escherichia coli.

Q4QRB4	TBB3_RAT	Tubulin beta-3 chain	12234689	Cloning and characterization of the 5'-flanking region of the rat neuron-specific class III beta-tubulin gene.

P13637	AT1A3_HUMAN	Sodium/potassium-transporting ATPase subunit alpha-3	15260953	Mutations in the Na(+)/K(+)-ATPase alpha-3 gene ATP1A3 are associated with rapid-onset dystonia parkinsonism.

P78563	RED1_HUMAN	Double-stranded RNA-specific editase 1	9111310	Editing of glutamate receptor B subunit ion channel RNAs by four alternatively spliced DRADA2 double-stranded RNA adenosine deaminases.

Q6GSS7	H2A2A_MOUSE	Histone H2A type 2-A	8858345	Characterization of the 55-kb mouse histone gene cluster on chromosome 3.

Q62796	RBP1_RAT	RalA-binding protein 1	7623849	Identification and characterization of Ral-binding protein 1, a potential downstream target of Ral GTPases.

P19320	VCAM1_HUMAN	Vascular cell adhesion protein 1	1377228	Activated endothelium binds lymphocytes through a novel binding site in the alternately spliced domain of vascular cell adhesion molecule- 1.

Q24338	ESC_DROME	Polycomb protein esc	12408863	Drosophila Enhancer of zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites.

Q12421	CIS1_YEAST	Autophagy-related protein 31	14562095	Global analysis of protein localization in budding yeast.

O48963	PHOT1_ARATH	Phototropin-1	9831559	Arabidopsis NPH1: a flavoprotein with the properties of a photoreceptor for phototropism.

P25293	NAP1_YEAST	Nucleosome assembly protein	7622566	Members of the NAP/SET family of proteins interact specifically with B-type cyclins.

Q9JHE6	HES6_MOUSE	Transcription cofactor HES-6	10851137	The bHLH gene Hes6, an inhibitor of Hes1, promotes neuronal differentiation.

Q9LXE5	DRM1_ARATH	DNA (cytosine-5)-methyltransferase DRM1	12151602	Locus-specific control of asymmetric and CpNpG methylation by the DRM and CMT3 methyltransferase genes.

Q9M643	CCI1_ARATH	Cycloeucalenol cycloisomerase	10788449	Functional cloning of an Arabidopsis thaliana cDNA encoding cycloeucalenol cycloisomerase.

P35131	UBC8_ARATH	Ubiquitin-conjugating enzyme E2 8	16339806	Genome analysis and functional characterization of the E2 and RING- type E3 ligase ubiquitination enzymes of Arabidopsis.

Q06211	MMS1_YEAST	Methyl methanesulfonate-sensitivity protein 1	11779788	Multiple regulators of Ty1 transposition in Saccharomyces cerevisiae have conserved roles in genome maintenance.

Q9U4H5	AMX_DROME	TM2 domain-containing protein almondex	14595834	Differential requirements for the neurogenic gene almondex during Drosophila melanogaster development.

O04663	IF4E2_ARATH	Eukaryotic translation initiation factor 4E-2	11117257	Plant lipoxygenase 2 is a translation initiation factor-4E-binding protein.

Q9HC98	NEK6_HUMAN	Serine/threonine-protein kinase Nek6	12054534	Identification and characterization of Nek6 protein kinase, a potential human homolog of NIMA histone H3 kinase.

P09467	F16P1_HUMAN	Fructose-1,6-bisphosphatase 1	7558035	Human fructose-1,6-bisphosphatase gene (FBP1): exon-intron organization, localization to chromosome bands 9q22.2-q22.3, and mutation screening in subjects with fructose-1,6-bisphosphatase deficiency.

P47989	XDH_HUMAN	Xanthine dehydrogenase/oxidase	8224915	Cloning of the cDNA encoding human xanthine dehydrogenase (oxidase): structural analysis of the protein and chromosomal location of the gene.

O74308	YOG2_SCHPO	Uncharacterized transcriptional regulatory protein C15D4.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O08560	DGKZ_RAT	Diacylglycerol kinase zeta	8855332	A 104-kDa diacylglycerol kinase containing ankyrin-like repeats localizes in the cell nucleus.

P49069	CAMLG_HUMAN	Calcium signal-modulating cyclophilin ligand	7522304	Calcium signalling in T cells stimulated by a cyclophilin B-binding protein.

P09619	PGFRB_HUMAN	Beta-type platelet-derived growth factor receptor	10805725	Class II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptors.

P77555	ALLD_ECOLI	Ureidoglycolate dehydrogenase	10601204	Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.

Q9R1K8	GRP1_RAT	RAS guanyl-releasing protein 1	9789079	A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia.

P38759	PEP11_YEAST	Vacuolar protein sorting-associated protein 29	9700157	A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeast.

P25300	BUD5_YEAST	Bud site selection protein 5	12176366	Subcellular localization of Axl1, the cell type-specific regulator of polarity.

Q9Y705	ALP4_SCHPO	Spindle pole body component alp4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9JHI4	S13A1_MOUSE	Solute carrier family 13 member 1	10766815	The mouse Na+-sulfate cotransporter gene Nas1: cloning, tissue distribution, gene structure, chromosomal assignment, and transcriptional regulation by vitamin D.

Q08959	YP206_YEAST	Probable glycerophosphodiester phosphodiesterase YPL206C	12514182	Bipartite signals mediate subcellular targeting of tail-anchored membrane proteins in Saccharomyces cerevisiae.

P32486	KRE6_YEAST	Beta-glucan synthesis-associated protein KRE6	7929594	Characterization of the yeast (1-->6)-beta-glucan biosynthetic components, Kre6p and Skn1p, and genetic interactions between the PKC1 pathway and extracellular matrix assembly.

O43347	MSI1H_HUMAN	RNA-binding protein Musashi homolog 1	9790759	The human Musashi homolog 1 (MSI1) gene encoding the homologue of Musashi/Nrp-1, a neural RNA-binding protein putatively expressed in CNS stem cells and neural progenitor cells.

Q9ZVD0	SRRT_ARATH	Serrate RNA effector molecule	11402159	The arabidopsis serrate gene encodes a zinc-finger protein required for normal shoot development.

Q8GXU8	LPAT1_ARATH	1-acyl-sn-glycerol-3-phosphate acyltransferase 1, chloroplastic	12766230	Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.

P52594	AGFG1_HUMAN	Arf-GAP domain and FG repeats-containing protein 1	7634337	Identification of a novel cellular cofactor for the Rev/Rex class of retroviral regulatory proteins.

Q13438	OS9_HUMAN	Protein OS-9	19084021	Mammalian OS-9 is upregulated in response to endoplasmic reticulum stress and facilitates ubiquitination of misfolded glycoproteins.

Q8NG66	NEK11_HUMAN	Serine/threonine-protein kinase Nek11	15161910	Nucleolar Nek11 is a novel target of Nek2A in G1/S-arrested cells.

Q9CZA6	NDE1_MOUSE	Nuclear distribution protein nudE homolog 1	11163258	LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome.

Q9SCT4	IMK2_ARATH	Probably inactive leucine-rich repeat receptor-like protein kinase IMK2	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q9UT74	LYS4_SCHPO	Homoaconitase, mitochondrial	16491385	Cloning the Schizosaccharomyces pombe lys2 (+) gene and construction of new molecular genetic tools.

Q8BH64	EHD2_MOUSE	EH domain-containing protein 2	18502764	The endocytic recycling protein EHD2 interacts with myoferlin to regulate myoblast fusion.

Q8VD46	ASZ1_MOUSE	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1	19730684	GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline.

Q12238	UVI31_SCHPO	UV-induced protein uvi31	12521307	Regulation of septation and cytokinesis during resumption of cell division requires uvi31+, a UV-inducible gene of fission yeast.

P46060	RAGP1_HUMAN	Ran GTPase-activating protein 1	7878053	Human RanGTPase-activating protein RanGAP1 is a homologue of yeast Rna1p involved in mRNA processing and transport.

O94271	YORN_SCHPO	Uncharacterized RING finger protein P8B7.23	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

Q8ML70	IM10_DROME	Immune-induced peptides	9736738	Differential display of peptides induced during the immune response of Drosophila: a matrix-assisted laser desorption ionization time-of- flight mass spectrometry study.

Q9JLC3	MSRB1_MOUSE	Methionine-R-sulfoxide reductase B1	14699060	Methionine sulfoxide reduction in mammals: characterization of methionine-R-sulfoxide reductases.

P48563	MON2_YEAST	Protein MON2	16301316	Mon2, a relative of large Arf exchange factors, recruits Dop1 to the Golgi apparatus.

Q8INB9	AKT1_DROME	RAC serine/threonine-protein kinase	10587646	Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB.

Q9NTJ3	SMC4_HUMAN	Structural maintenance of chromosomes protein 4	11136719	Chromosome condensation by a human condensin complex in Xenopus egg extracts.

P70005	GAT6B_XENLA	GATA-binding factor 6-B	9029155	Over-expression of GATA-6 in Xenopus embryos blocks differentiation of heart precursors.

P19474	RO52_HUMAN	E3 ubiquitin-protein ligase TRIM21	16880511	Regulation of p27 degradation and S-phase progression by Ro52 RING finger protein.

Q9HCE1	MOV10_HUMAN	Putative helicase MOV-10	16289642	Identification of novel argonaute-associated proteins.

P08311	CATG_HUMAN	Cathepsin G	8194606	Identification of the U-937 membrane-associated proteinase interacting with the V3 loop of HIV-1 gp120 as cathepsin G.

Q99941	ATF6B_HUMAN	Cyclic AMP-dependent transcription factor ATF-6 beta	8870652	The gene G13 in the class III region of the human MHC encodes a potential DNA-binding protein.

P14618	KPYM_HUMAN	Pyruvate kinase isozymes M1/M2	18191611	Pyruvate kinase isozyme type M2 (PKM2) interacts and cooperates with Oct-4 in regulating transcription.

P0ACC7	GLMU_ECOLI	Bifunctional protein glmU	8407787	Identification of the glmU gene encoding N-acetylglucosamine-1- phosphate uridyltransferase in Escherichia coli.

O15126	SCAM1_HUMAN	Secretory carrier-associated membrane protein 1	9378760	Three mammalian SCAMPs (secretory carrier membrane proteins) are highly related products of distinct genes having similar subcellular distributions.

P49809	EGL10_CAEEL	Regulator of G-protein signaling egl-10	8548815	EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins.

P0ACN4	ALLR_ECOLI	HTH-type transcriptional repressor AllR	10601204	Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.

P01889	1B07_HUMAN	HLA class I histocompatibility antigen, B-7 alpha chain	518865	Complete amino acid sequence of a papain-solubilized human histocompatibility antigen, HLA-B7. 2. Sequence determination and search for homologies.

Q9SB92	WUS_ARATH	Protein WUSCHEL	10761929	The stem cell population of Arabidopsis shoot meristems in maintained by a regulatory loop between the CLAVATA and WUSCHEL genes.

Q9Y3P8	SIT1_HUMAN	Signaling threshold-regulating transmembrane adapter 1	11433379	Structural and functional dissection of the cytoplasmic domain of the transmembrane adaptor protein SIT (SHP2-interacting transmembrane adaptor protein).

Q58FA4	E2F8_MOUSE	Transcription factor E2F8	15722552	Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation.

P51400	RED1_RAT	Double-stranded RNA-specific editase 1	8559253	A mammalian RNA editing enzyme.

Q7KZI7	MARK2_HUMAN	Serine/threonine-protein kinase MARK2	14976552	LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1.

O75438	NDUB1_HUMAN	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

O94813	SLIT2_HUMAN	Slit homolog 2 protein	9813312	Cloning and expressions of three mammalian homologues of Drosophila slit suggest possible roles for Slit in the formation and maintenance of the nervous system.

Q12082	YD157_YEAST	Uncharacterized protein YDL157C, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

P97431	IRF6_MOUSE	Interferon regulatory factor 6	17041603	Irf6 is a key determinant of the keratinocyte proliferation- differentiation switch.

Q9S7D9	ACCR1_ARATH	Serine/threonine-protein kinase-like protein CCR1	18539132	Dimerization properties of the transmembrane domains of Arabidopsis CRINKLY4 receptor-like kinase and homologs.

O42963	NUP44_SCHPO	Nucleoporin nup44	15116432	Identification of genes encoding putative nucleoporins and transport factors in the fission yeast Schizosaccharomyces pombe: a deletion analysis.

Q9LDH0	XYLT_ARATH	Beta-(1,2)-xylosyltransferase	10781814	Molecular cloning and functional expression of beta 1,2- xylosyltransferase cDNA from Arabidopsis thaliana.

Q8K4G5	ABLM1_MOUSE	Actin-binding LIM protein 1	9245787	Molecular characterization of abLIM, a novel actin-binding and double zinc finger protein.

Q1XH17	TRI72_MOUSE	Tripartite motif-containing protein 72	19043407	MG53 nucleates assembly of cell membrane repair machinery.

P46310	FAD3C_ARATH	Omega-3 fatty acid desaturase, chloroplastic	8226956	A gene encoding a chloroplast omega-3 fatty acid desaturase complements alterations in fatty acid desaturation and chloroplast copy number of the fad7 mutant of Arabidopsis thaliana.

Q96SB4	SRPK1_HUMAN	Serine/threonine-protein kinase SRPK1	11509566	Cloning and characterization of an alternatively spliced form of SR protein kinase 1 that interacts specifically with scaffold attachment factor-B.

Q9R0K7	AT2B2_MOUSE	Plasma membrane calcium-transporting ATPase 2	9668038	Balance and hearing deficits in mice with a null mutation in the gene encoding plasma membrane Ca2+-ATPase isoform 2.

Q8WR51	OFUT2_CAEEL	GDP-fucose protein O-fucosyltransferase 2	15233996	The Caenorhabditis elegans ortholog of C21orf80, a potential new protein O-fucosyltransferase, is required for normal development.

P11832	NIA1_ARATH	Nitrate reductase [NADH] 1	8510658	Identification and characterization of a chlorate-resistant mutant of Arabidopsis thaliana with mutations in both nitrate reductase structural genes NIA1 and NIA2.

O74962	PANK_SCHPO	Pantothenate kinase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O60449	LY75_HUMAN	Lymphocyte antigen 75	9553150	cDNA cloning of human DEC-205, a putative antigen-uptake receptor on dendritic cells.

O94332	RRN11_SCHPO	RNA polymerase I-specific transcription initiation factor rrn11	12095692	Characterization of a fission yeast subunit of an RNA polymerase I essential transcription initiation factor, SpRrn7h/TAF(I)68, that bridges yeast and mammals: association with SpRrn11h and the core ribosomal RNA gene promoter.

P00175	CYB2_YEAST	Cytochrome b2, mitochondrial	11502169	Yeast mitochondrial dehydrogenases are associated in a supramolecular complex.

Q61029	LAP2B_MOUSE	Lamina-associated polypeptide 2, isoforms beta/delta/epsilon/gamma	11591818	Nuclear membrane protein LAP2beta mediates transcriptional repression alone and together with its binding partner GCL (germ-cell-less).

Q0E7J7	STN1_SCHPO	Protein stn1	17715303	Protection of telomeres by a conserved Stn1-Ten1 complex.

P36118	NTR2_YEAST	Pre-mRNA-splicing factor NTR2	14562095	Global analysis of protein localization in budding yeast.

Q90X46	GP161_DANRE	G-protein coupled receptor 161	18755178	The orphan G protein-coupled receptor 161 is required for left-right patterning.

Q06705	CSR1_YEAST	Phosphatidylinositol transfer protein CSR1	12869188	Subcellular localization of yeast Sec14 homologues and their involvement in regulation of phospholipid turnover.

O75417	DPOLQ_HUMAN	DNA polymerase theta	10395804	Cloning and chromosomal mapping of the human DNA polymerase theta (POLQ), the eighth human DNA polymerase.

Q6PDY0	CC85B_MOUSE	Coiled-coil domain-containing protein 85B	15644333	Delta-interacting protein A, a new inhibitory partner of CCAAT/enhancer-binding protein beta, implicated in adipocyte differentiation.

Q9Y2W7	CSEN_HUMAN	Calsenilin	10078534	DREAM is a Ca2+-regulated transcriptional repressor.

Q13308	PTK7_HUMAN	Tyrosine-protein kinase-like 7	7478540	Colon carcinoma kinase-4 defines a new subclass of the receptor tyrosine kinase family.

Q01329	PTA1_YEAST	Pre-tRNA-processing protein PTA1	12819204	Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-ends.

Q9NQX1	PRDM5_HUMAN	PR domain zinc finger protein 5	17636019	Epigenetic regulation of protein-coding and microRNA genes by the Gfi1-interacting tumor suppressor PRDM5.

Q7TQ33	RGMB_MOUSE	RGM domain family member B	15671031	DRAGON, a bone morphogenetic protein co-receptor.

Q99594	TEAD3_HUMAN	Transcriptional enhancer factor TEF-5	19324877	TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition.

Q8K4B2	IRAK3_MOUSE	Interleukin-1 receptor-associated kinase 3	12150927	IRAK-M is a negative regulator of Toll-like receptor signaling.

Q9SJ25	CADH2_ARATH	Cinnamyl alcohol dehydrogenase 2	14745009	Functional reclassification of the putative cinnamyl alcohol dehydrogenase multigene family in Arabidopsis.

Q9Y2D0	CAH5B_HUMAN	Carbonic anhydrase 5B, mitochondrial	10409679	Human mitochondrial carbonic anhydrase VB: cDNA cloning, mRNA expression, subcellular localization, and mapping to chromosome X.

Q94BT6	ADO1_ARATH	Adagio protein 1	11260718	An Arabidopsis circadian clock component interacts with both CRY1 and phyB.

O59747	PDF1_SCHPO	Palmitoyl-protein thioesterase-dolichyl pyrophosphate phosphatase fusion 1	15075260	pdf1, a palmitoyl protein thioesterase 1 ortholog in Schizosaccharomyces pombe: a yeast model of infantile Batten disease.

P36156	GTO2_YEAST	Glutathione S-transferase omega-like 2	14562095	Global analysis of protein localization in budding yeast.

P77239	CUSB_ECOLI	Cation efflux system protein cusB	11283292	The product of the ybdE gene of the Escherichia coli chromosome is involved in detoxification of silver ions.

Q9Y3I1	FBX7_HUMAN	F-box only protein 7	10531035	Identification of a family of human F-box proteins.

P91870	SPD2_CAEEL	Spindle-defective protein 2	15068791	Centrosome maturation and duplication in C. elegans require the coiled-coil protein SPD-2.

Q13449	LSAMP_HUMAN	Limbic system-associated membrane protein	8666243	cDNA cloning and structural analysis of the human limbic-system- associated membrane protein (LAMP).

P10301	RRAS_HUMAN	Ras-related protein R-Ras	3098437	Structure of the human and murine R-ras genes, novel genes closely related to ras proto-oncogenes.

Q9QZX7	SRR_MOUSE	Serine racemase	15536068	Serine racemase modulates intracellular D-serine levels through an alpha,beta-elimination activity.

Q98SN7	WNT2B_CHICK	Protein Wnt-2b	16258938	Expression patterns of Wnt genes during development of an anterior part of the chicken eye.

O08967	CYH3_MOUSE	Cytohesin-3	10828067	Interaction of GRASP, a protein encoded by a novel retinoic acid- induced gene, with members of the cytohesin family of guanine nucleotide exchange factors.

O13864	IMB1_SCHPO	Importin subunit beta-1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12906	ILF3_HUMAN	Interleukin enhancer-binding factor 3	10749851	Protein-arginine methyltransferase I, the predominant protein- arginine methyltransferase in cells, interacts with and is regulated by interleukin enhancer-binding factor 3.

Q9Y240	CLC11_HUMAN	C-type lectin domain family 11 member A	11920266	Stem cell growth factor: in situ hybridization analysis on the gene expression, molecular characterization and in vitro proliferative activity of a recombinant preparation on primitive hematopoietic progenitor cells.

P80668	FEAB_ECOLI	Phenylacetaldehyde dehydrogenase	9109378	Molecular characterization of PadA, a phenylacetaldehyde dehydrogenase from Escherichia coli.

P23654	NRT_DROME	Neurotactin	2100266	Drosophila neurotactin, a surface glycoprotein with homology to serine esterases, is dynamically expressed during embryogenesis.

P05527	HMIN_DROME	Homeobox protein invected	9165116	Requirement for engrailed and invected genes reveals novel regulatory interactions between engrailed/invected, patched, gooseberry and wingless during Drosophila neurogenesis.

Q09172	PP2C2_SCHPO	Protein phosphatase 2C homolog 2	7859738	Counteractive roles of protein phosphatase 2C (PP2C) and a MAP kinase kinase homolog in the osmoregulation of fission yeast.

Q9SCU5	WNK5_ARATH	Probable serine/threonine-protein kinase WNK5	12506983	Compilation and characterization of a novel WNK family of protein kinases in Arabiodpsis thaliana with reference to circadian rhythms.

P87310	MED10_SCHPO	Mediator of RNA polymerase II transcription subunit 10	11572939	Analysis of Schizosaccharomyces pombe mediator reveals a set of essential subunits conserved between yeast and metazoan cells.

P34144	RAC1A_DICDI	Rho-related protein rac1A	15509655	Cellular distribution and functions of wild-type and constitutively activated Dictyostelium PakB.

Q03720	SLO_DROME	Calcium-activated potassium channel slowpoke	10234050	Simultaneous binding of two protein kinases to a calcium-dependent potassium channel.

P11021	GRP78_HUMAN	78 kDa glucose-regulated protein	18502753	Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiP.

P34227	PRX1_YEAST	Mitochondrial peroxiredoxin PRX1	10681558	Distinct physiological functions of thiol peroxidase isoenzymes in Saccharomyces cerevisiae.

Q8BP71	RBM9_MOUSE	RNA-binding protein 9	11401487	Androgens regulate the mammalian homologues of invertebrate sex determination genes tra-2 and fox-1.

P39743	RV167_YEAST	Reduced viability upon starvation protein 167	10388809	In vivo analysis of the domains of yeast Rvs167p suggests Rvs167p function is mediated through multiple protein interactions.

O74852	YQ92_SCHPO	Uncharacterized MFS-type transporter C18.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P46998	FMP33_YEAST	Mitochondrial membrane protein FMP33	14562095	Global analysis of protein localization in budding yeast.

Q04693	RSE1_YEAST	Pre-mRNA-splicing factor RSE1	9819400	A link between secretion and pre-mRNA processing defects in Saccharomyces cerevisiae and the identification of a novel splicing gene, RSE1.

P36097	TTI1_YEAST	TEL2-interacting protein 1	14562095	Global analysis of protein localization in budding yeast.

Q9ESN9	JIP3_MOUSE	C-Jun-amino-terminal kinase-interacting protein 3	11106729	Kinesin-dependent axonal transport is mediated by the Sunday Driver (SYD) protein.

P39059	COFA1_HUMAN	Collagen alpha-1(XV) chain	9651385	Complete exon-intron organization of the human gene for the alpha1 chain of type XV collagen (COL15A1) and comparison with the homologous COL18A1 gene.

Q9VJJ7	TRPG_DROME	Transient receptor potential-gamma protein	10896160	TRPgamma, a Drosophila TRP-related subunit, forms a regulated cation channel with TRPL.

Q7T322	NAA35_DANRE	N-alpha-acetyltransferase 35, NatC auxiliary subunit	16484612	Embryonic growth-associated protein is one subunit of a novel N- terminal acetyltransferase complex essential for embryonic vascular development.

Q8BIJ7	RUFY1_MOUSE	RUN and FYVE domain-containing protein 1	11172003	A FYVE-finger-containing protein, Rabip4, is a Rab4 effector involved in early endosomal traffic.

P31939	PUR9_HUMAN	Bifunctional purine biosynthesis protein PURH	14966129	Crystal structures of human bifunctional enzyme aminoimidazole-4- carboxamide ribonucleotide transformylase/IMP cyclohydrolase in complex with potent sulfonyl-containing antifolates.

P51124	GRAM_HUMAN	Granzyme M	7713495	The human Met-ase gene (GZMM): structure, sequence, and close physical linkage to the serine protease gene cluster on 19p13.3.

Q8VYM2	PHT11_ARATH	Inorganic phosphate transporter 1-1	9192698	Overexpression of an Arabidopsis thaliana high-affinity phosphate transporter gene in tobacco cultured cells enhances cell growth under phosphate-limited conditions.

P0C7A3	MBOA4_MOUSE	Ghrelin O-acyltransferase	18267071	Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone.

Q10268	MAC1_SCHPO	Membrane-anchored protein 1	12206652	Mac1, a fission yeast transmembrane protein localizing to the poles and septum, is required for correct cell separation at high temperatures.

P15999	ATPA_RAT	ATP synthase subunit alpha, mitochondrial	2137825	Mitochondrial ATP synthase. cDNA cloning, amino acid sequence, overexpression, and properties of the rat liver alpha subunit.

Q9XZ58	CSN5_DROME	COP9 signalosome complex subunit 5	10531038	The COP9 signalosome is essential for development of Drosophila melanogaster.

Q15334	L2GL1_HUMAN	Lethal(2) giant larvae protein homolog 1	7542763	A human homologue of the Drosophila tumour suppressor gene l(2)gl maps to 17p11.2-12 and codes for a cytoskeletal protein that associates with nonmuscle myosin II heavy chain.

Q8GYJ3	KRP4_ARATH	Cyclin-dependent kinase inhibitor 4	18948957	Control of plant germline proliferation by SCF(FBL17) degradation of cell cycle inhibitors.

Q99638	RAD9A_HUMAN	Cell cycle checkpoint control protein RAD9A	10884395	The human checkpoint protein hRad17 interacts with the PCNA-like proteins hRad1, hHus1, and hRad9.

P28007	GAR1_YEAST	H/ACA ribonucleoprotein complex subunit 1	9556561	Gar1p binds to the small nucleolar RNAs snR10 and snR30 in vitro through a nontypical RNA binding element.

P38291	POP7_YEAST	Ribonucleases P/MRP protein subunit POP7	9620854	Purification and characterization of the nuclear RNase P holoenzyme complex reveals extensive subunit overlap with RNase MRP.

Q6UWI2	PARM1_HUMAN	Prostate androgen-regulated mucin-like protein 1	18027867	Human PARM-1 is a novel mucin-like, androgen-regulated gene exhibiting proliferative effects in prostate cancer cells.

O54972	MTG16_MOUSE	Protein CBFA2T3	15231665	AML1-ETO decreases ETO-2 (MTG16) interactions with nuclear receptor corepressor, an effect that impairs granulocyte differentiation.

P48303	S1PR1_RAT	Sphingosine 1-phosphate receptor 1	7959012	Cloning of the rat edg-1 immediate-early gene: expression pattern suggests diverse functions.

Q9SA18	AKH1_ARATH	Bifunctional aspartokinase/homoserine dehydrogenase 1, chloroplastic	16216875	Identification of six novel allosteric effectors of Arabidopsis thaliana aspartate kinase-homoserine dehydrogenase isoforms. Physiological context sets the specificity.

O88446	S22A3_RAT	Solute carrier family 22 member 3	9632645	Cloning and functional characterization of a potential-sensitive, polyspecific organic cation transporter (OCT3) most abundantly expressed in placenta.

Q12768	STRUM_HUMAN	WASH complex subunit strumpellin	19922875	The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex.

Q12164	YL023_YEAST	UPF0121 membrane protein YLL023C	14562095	Global analysis of protein localization in budding yeast.

Q9SCZ4	FERON_ARATH	Receptor-like protein kinase FERONIA	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q12230	LSP1_YEAST	Sphingolipid long chain base-responsive protein LSP1	16496001	Eisosomes mark static sites of endocytosis.

P10768	ESTD_HUMAN	S-formylglutathione hydrolase	3164702	Human esterase D gene: complete cDNA sequence, genomic structure, and application in the genetic diagnosis of human retinoblastoma.

P42043	HEMH1_ARATH	Ferrochelatase-1, chloroplastic/mitochondrial	9753778	Two different genes encode ferrochelatase in Arabidopsis: mapping, expression and subcellular targeting of the precursor proteins.

A8MPY1	GBRR3_HUMAN	Gamma-aminobutyric acid receptor subunit rho-3	10542332	Genetic linkage and radiation hybrid mapping of the three human GABA(C) receptor rho subunit genes: GABRR1, GABRR2 and GABRR3.

Q9BST9	RTKN_HUMAN	Rhotekin	16007136	Possible role of Rho/Rhotekin signaling in mammalian septin organization.

P38987	TEM1_YEAST	Protein TEM1	12628189	Exit from exit: resetting the cell cycle through Amn1 inhibition of G protein signaling.

O15370	SOX12_HUMAN	Transcription factor SOX-12	9215677	SOX22 is a new member of the SOX gene family, mainly expressed in human nervous tissue.

Q93WI9	HD3A_ORYSJ	Protein HEADING DATE 3A	17446351	Hd3a protein is a mobile flowering signal in rice.

Q9JIR1	RIMB2_RAT	RIMS-binding protein 2	10748113	The RIM/NIM family of neuronal C2 domain proteins. Interactions with Rab3 and a new class of Src homology 3 domain proteins.

Q9WUD2	TRPV2_RAT	Transient receptor potential cation channel subfamily V member 2	10201375	A capsaicin-receptor homologue with a high threshold for noxious heat.

Q99689	FEZ1_HUMAN	Fasciculation and elongation protein zeta-1	9096408	The Caenorhabditis elegans gene unc-76 and its human homologs define a new gene family involved in axonal outgrowth and fasciculation.

Q9HE12	YI31_SCHPO	Putative purine permease C1399.01c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P49675	STAR_HUMAN	Steroidogenic acute regulatory protein, mitochondrial	7761400	Human steroidogenic acute regulatory protein: functional activity in COS-1 cells, tissue-specific expression, and mapping of the structural gene to 8p11.2 and a pseudogene to chromosome 13.

Q99MR9	PPR3A_MOUSE	Protein phosphatase 1 regulatory subunit 3A	11361130	Gene structure and expression of the targeting subunit, RGL, of the muscle-specific glycogen-associated type 1 protein phosphatase, PP1G.

Q06551	ERFB_YEAST	Palmitoyltransferase ERF2	10490616	Erf2, a novel gene product that affects the localization and palmitoylation of Ras2 in Saccharomyces cerevisiae.

O13766	MDE10_SCHPO	Zinc metalloprotease mde10	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9SE97	FH1_ARATH	Formin-like protein 1	15994911	The formin homology 1 domain modulates the actin nucleation and bundling activity of Arabidopsis FORMIN1.

P53941	IMP4_YEAST	U3 small nucleolar ribonucleoprotein protein IMP4	12068309	A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis.

Q94CL9	KRP7_ARATH	Cyclin-dependent kinase inhibitor 7	16376885	Arabidopsis KRPs have distinct inhibitory activity toward cyclin D2- associated kinases, including plant-specific B-type cyclin-dependent kinase.

Q9NUD9	PIGV_HUMAN	GPI mannosyltransferase 2	15720390	Saccharomyces cerevisiae Ybr004c and its human homologue are required for addition of the second mannose during glycosylphosphatidylinositol precursor assembly.

Q92581	SL9A6_HUMAN	Sodium/hydrogen exchanger 6	9507001	Identification of a mitochondrial Na+/H+ exchanger.

Q8IL52	YSNF1_PLAF7	Uncharacterized protein PF14_0397	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

O23051	KAO1_ARATH	Ent-kaurenoic acid oxidase 1	11722763	A plastid envelope location of Arabidopsis ent-kaurene oxidase links the plastid and endoplasmic reticulum steps of the gibberellin biosynthesis pathway.

P39015	STM1_YEAST	Suppressor protein STM1	15654430	Similarity between the association factor of ribosomal subunits and the protein Stm1p from Saccharomyces cerevisiae.

Q92782	DPF1_HUMAN	Zinc finger protein neuro-d4	8812431	The d4 gene family in the human genome.

O01352	DJ_DROME	Sperm-specific protein Don juan	9788872	Flagellar mitochondrial association of the male-specific Don Juan protein in Drosophila spermatozoa.

Q8R0H9	GGA1_MOUSE	ADP-ribosylation factor-binding protein GGA1	19864490	Consortin, a trans-Golgi network cargo receptor for the plasma membrane targeting and recycling of connexins.

O13945	PPK9_SCHPO	Protein kinase domain-containing protein ppk9	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O54921	EXOC2_RAT	Exocyst complex component 2	9405631	Subunit structure of the mammalian exocyst complex.

Q99720	SGMR1_HUMAN	Sigma non-opioid intracellular receptor 1	9341151	Purification and characterization of the human SR 31747A-binding protein. A nuclear membrane protein related to yeast sterol isomerase.

O74511	EKC1_SCHPO	Extragenic suppressor of kinetochore protein 1	12773390	The role of Ppe1/PP6 phosphatase for equal chromosome segregation in fission yeast kinetochore.

O88506	STK39_RAT	STE20/SPS1-related proline-alanine-rich protein kinase	9675032	Molecular cloning and characterization of a novel Ste20-related protein kinase enriched in neurons and transporting epithelia.

P05408	7B2_HUMAN	Neuroendocrine protein 7B2	7913882	7B2 is a neuroendocrine chaperone that transiently interacts with prohormone convertase PC2 in the secretory pathway.

Q9UBL3	ASH2L_HUMAN	Set1/Ash2 histone methyltransferase complex subunit ASH2	15199122	Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression.

O24520	HBL1_ARATH	Non-symbiotic hemoglobin 1	9342391	Two hemoglobin genes in Arabidopsis thaliana: the evolutionary origins of leghemoglobins.

Q9EPM5	SYNCI_MOUSE	Syncoilin	11053421	Syncoilin, a novel member of the intermediate filament superfamily that interacts with alpha-dystrobrevin in skeletal muscle.

Q23985	DTX_DROME	Protein deltex	11861487	Involvement of a proline-rich motif and RING-H2 finger of Deltex in the regulation of Notch signaling.

Q42525	HXK1_ARATH	Hexokinase-1	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

O88668	CREG1_MOUSE	Protein CREG1	9710587	A cellular repressor of E1A-stimulated genes that inhibits activation by E2F.

Q9R044	NPHN_RAT	Nephrin	11880318	Podocyte slit-diaphragm protein nephrin is linked to the actin cytoskeleton.

Q8CDG1	PIWL2_MOUSE	Piwi-like protein 2	18381894	DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes.

Q9VHP0	DDX3_DROME	ATP-dependent RNA helicase bel	15572142	Belle is a Drosophila DEAD-box protein required for viability and in the germ line.

P0C2H6	RL27A_YEAST	60S ribosomal protein L27-A	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

P47069	MPS3_YEAST	Spindle pole body assembly component MPS3	16923827	The Sad1-UNC-84 homology domain in Mps3 interacts with Mps2 to connect the spindle pole body with the nuclear envelope.

P36104	SWD2_YEAST	COMPASS component SWD2	11805083	COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression.

P53168	DUO1_YEAST	DASH complex subunit DUO1	15664196	Formation of a dynamic kinetochore-microtubule interface through assembly of the Dam1 ring complex.

Q64288	OMP_MOUSE	Olfactory marker protein	12911636	Identification of members of the Bex gene family as olfactory marker protein (OMP) binding partners.

Q96S37	S22AC_HUMAN	Solute carrier family 22 member 12	12024214	Molecular identification of a renal urate anion exchanger that regulates blood urate levels.

P34082	FAS2_DROME	Fasciclin-2	1913818	Genetic analysis of growth cone guidance in Drosophila: fasciclin II functions as a neuronal recognition molecule.

O81283	TC159_ARATH	Translocase of chloroplast 159, chloroplastic	12766230	Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.

Q26458	ESC_DROVI	Polycomb protein esc	8541211	The extra sex combs protein is highly conserved between Drosophila virilis and Drosophila melanogaster.

P08217	CEL2A_HUMAN	Chymotrypsin-like elastase family member 2A	2834346	Molecular cloning and expression in Escherichia coli of a cDNA encoding human pancreatic elastase 2.

P05113	IL5_HUMAN	Interleukin-5	3024129	Cloning of cDNA for human T-cell replacing factor (interleukin-5) and comparison with the murine homologue.

P17789	TTKB_DROME	Protein tramtrack, beta isoform	12384587	The Drosophila transcription factor tramtrack (TTK) interacts with Trithorax-like (GAGA) and represses GAGA-mediated activation.

Q6TMA8	ANGL4_RAT	Angiopoietin-related protein 4	14570927	Oligomerization and regulated proteolytic processing of angiopoietin- like protein 4.

P40961	PHB1_YEAST	Prohibitin-1	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q13148	TADBP_HUMAN	TAR DNA-binding protein 43	7745706	Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs.

P68209	SUCA1_ARATH	Succinyl-CoA ligase [GDP-forming] subunit alpha-1, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P40975	PMP2_YEAST	Plasma membrane ATPase proteolipid 2	8063750	Two distinct genes encode small isoproteolipids affecting plasma membrane H(+)-ATPase activity of Saccharomyces cerevisiae.

P43123	UAP1_YEAST	UDP-N-acetylglucosamine pyrophosphorylase	9603950	The eukaryotic UDP-N-acetylglucosamine pyrophosphorylases: gene cloning, protein expression, and catalytic mechanism.

Q8TEP8	CE192_HUMAN	Centrosomal protein of 192 kDa	17980596	Human Cep192 is required for mitotic centrosome and spindle assembly.

P12861	HSP83_TRYBB	Heat shock protein 83	2515434	A transcriptional analysis of the Trypanosoma brucei hsp83 gene cluster.

Q94AH6	CUL1_ARATH	Cullin-1	12381738	The AtRbx1 protein is part of plant SCF complexes, and its down- regulation causes severe growth and developmental defects.

P43248	MSH2_DROME	DNA mismatch repair protein spellchecker 1	10077620	Microsatellite instability in Drosophila spellchecker1 (MutS homolog) mutants.

Q66T02	PKHG5_MOUSE	Pleckstrin homology domain-containing family G member 5	16467373	A PDZ-binding motif as a critical determinant of Rho guanine exchange factor function and cell phenotype.

Q12245	POC4_YEAST	Proteasome chaperone 4	17707236	20S proteasome assembly is orchestrated by two distinct pairs of chaperones in yeast and in mammals.

Q9C8J2	NIFU5_ARATH	NifU-like protein 5, mitochondrial	12553879	Iron-sulphur cluster assembly in plants: distinct NFU proteins in mitochondria and plastids from Arabidopsis thaliana.

Q12908	NTCP2_HUMAN	Ileal sodium/bile acid cotransporter	7592981	Identification of a mutation in the ileal sodium-dependent bile acid transporter gene that abolishes transport activity.

Q12221	PUF2_YEAST	mRNA-binding protein PUF2	14562095	Global analysis of protein localization in budding yeast.

O14901	KLF11_HUMAN	Krueppel-like factor 11	9748269	Molecular cloning and characterization of TIEG2 reveals a new subfamily of transforming growth factor-beta-inducible Sp1-like zinc finger-encoding genes involved in the regulation of cell growth.

Q91V12	BACH_MOUSE	Cytosolic acyl coenzyme A thioester hydrolase	11834298	Characterization of mouse homolog of brain acyl-CoA hydrolase: molecular cloning and neuronal localization.

Q9HCS4	TF7L1_HUMAN	Transcription factor 7-like 1	11085512	Mitomycin C resistance induced by TCF-3 overexpression in gastric cancer cell line MKN28 is associated with DT-diaphorase down- regulation.

Q9WTU6	MK09_MOUSE	Mitogen-activated protein kinase 9	10811224	JNK is required for effector T-cell function but not for T-cell activation.

O48737	TRXM1_ARATH	Thioredoxin M1, chloroplastic	19631646	Redox regulation of chloroplastic glucose-6-phosphate dehydrogenase: a new role for f-type thioredoxin.

Q01814	AT2B2_HUMAN	Plasma membrane calcium-transporting ATPase 2	1313367	Microdiversity of human-plasma-membrane calcium-pump isoform 2 generated by alternative RNA splicing in the N-terminal coding region.

Q9FUJ2	CKX4_ARATH	Cytokinin dehydrogenase 4	11154345	Molecular and biochemical characterization of a cytokinin oxidase from maize.

Q9NZ52	GGA3_HUMAN	ADP-ribosylation factor-binding protein GGA3	12505986	Divalent interaction of the GGAs with the Rabaptin-5-Rabex-5 complex.

Q8K1M7	FAM5C_RAT	Protein FAM5C	15193423	Identification and characterization of novel developmentally regulated neural-specific proteins, BRINP family.

P04206	KV307_HUMAN	Ig kappa chain V-III region GOL	3086710	Amino acid sequence of a light chain variable region of a human rheumatoid factor of the Wa idiotypic group, in part predicted by its reactivity with antipeptide antibodies.

Q9DEN3	FXD3B_XENLA	Forkhead box protein D3-B	11335115	Overexpression of the transcriptional repressor FoxD3 prevents neural crest formation in Xenopus embryos.

P40567	MSL1_YEAST	U2 small nuclear ribonucleoprotein B''	8649387	Identification and characterization of a yeast gene encoding the U2 small nuclear ribonucleoprotein particle B' protein.

Q94901	LARK_DROME	RNA-binding protein lark	8307324	A new biological rhythm mutant of Drosophila melanogaster that identifies a gene with an essential embryonic function.

P56960	EXOSX_MOUSE	Exosome component 10	10708524	Structure and localization of mouse Pmscl1 and Pmscl2 genes.

Q96IY1	NSL1_HUMAN	Kinetochore-associated protein NSL1 homolog	17981135	Human Blinkin/AF15q14 is required for chromosome alignment and the mitotic checkpoint through direct interaction with Bub1 and BubR1.

Q9EPL5	MMP1A_MOUSE	Interstitial collagenase A	11113146	Identification and enzymatic characterization of two diverging murine counterparts of human interstitial collagenase (MMP-1) expressed at sites of embryo implantation.

Q61271	ACV1B_MOUSE	Activin receptor type-1B	18039968	Ttrap is an essential modulator of Smad3-dependent Nodal signaling during zebrafish gastrulation and left-right axis determination.

P0A7I7	RIBA_ECOLI	GTP cyclohydrolase-2	8320220	Biosynthesis of riboflavin: cloning, sequencing, mapping, and expression of the gene coding for GTP cyclohydrolase II in Escherichia coli.

P55286	CADH8_HUMAN	Cadherin-8	2059658	Diversity of the cadherin family: evidence for eight new cadherins in nervous tissue.

O08604	RAE1C_MOUSE	Retinoic acid early-inducible protein 1-gamma	10894171	Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice.

Q12035	FCF2_YEAST	rRNA-processing protein FCF2	16762320	Fcf1p and Fcf2p are novel nucleolar Saccharomyces cerevisiae proteins involved in pre-rRNA processing.

P00747	PLMN_HUMAN	Plasminogen	9242524	Homozygous mutations in the plasminogen gene of two unrelated girls with ligneous conjunctivitis.

P97577	FEZ1_RAT	Fasciculation and elongation protein zeta-1	9971736	Mammalian homologue of the Caenorhabditis elegans UNC-76 protein involved in axonal outgrowth is a protein kinase C zeta-interacting protein.

P56192	SYMC_HUMAN	Methionyl-tRNA synthetase, cytoplasmic	8921912	Cloning of a human cDNA encoding a protein with high homology to yeast methionyl-tRNA synthetase.

O74992	YJZI_SCHPO	Uncharacterized membrane protein C338.18	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8RY71	ESP_ARATH	Epithiospecifier protein	11752388	The Arabidopsis epithiospecifier protein promotes the hydrolysis of glucosinolates to nitriles and influences Trichoplusia ni herbivory.

Q80Z37	TOPRS_MOUSE	E3 ubiquitin-protein ligase Topors	15735665	Topors, a p53 and topoisomerase I-binding RING finger protein, is a coactivator of p53 in growth suppression induced by DNA damage.

P32793	YSC84_YEAST	Protein YSC84	12388763	Novel proteins linking the actin cytoskeleton to the endocytic machinery in Saccharomyces cerevisiae.

O95295	SNAPN_HUMAN	SNARE-associated protein Snapin	10195194	Snapin: a SNARE-associated protein implicated in synaptic transmission.

Q13322	GRB10_HUMAN	Growth factor receptor-bound protein 10	15722337	Phosphorylation of grb10 regulates its interaction with 14-3-3.

O74910	RAF1_SCHPO	Rik1-associated factor 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q70KY3	LAC1_MELAO	Laccase-1	15474046	Laccase from Melanocarpus albomyces binds effectively to cellulose.

P48994	TRPL_DROME	Transient-receptor-potential-like protein	11514552	Regulation of Drosophila TRPL channels by immunophilin FKBP59.

P36143	GLG1_YEAST	Glycogenin-1	8524228	Requirement of the self-glucosylating initiator proteins Glg1p and Glg2p for glycogen accumulation in Saccharomyces cerevisiae.

Q12905	ILF2_HUMAN	Interleukin enhancer-binding factor 2	11739746	The RNA binding protein nuclear factor 90 functions as both a positive and negative regulator of gene expression in mammalian cells.

Q07139	ECT2_MOUSE	Protein ECT2	8464478	Oncogene ect2 is related to regulators of small GTP-binding proteins.

P40327	PRS4_YEAST	26S protease regulatory subunit 4 homolog	7721833	Cloning and expression of a yeast gene encoding a protein with ATPase activity and high identity to the subunit 4 of the human 26 S protease.

O14757	CHK1_HUMAN	Serine/threonine-protein kinase Chk1	12399544	Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints.

O42709	MCM10_SCHPO	DNA replication licensing factor mcm10	14766746	Primer utilization by DNA polymerase alpha-primase is influenced by its interaction with Mcm10p.

P12689	REV1_YEAST	DNA repair protein REV1	16452144	Saccharomyces cerevisiae polymerase zeta functions in mitochondria.

P55916	UCP3_HUMAN	Mitochondrial uncoupling protein 3	9180264	Uncoupling protein-3: a new member of the mitochondrial carrier family with tissue-specific expression.

P49743	RXRB_RAT	Retinoic acid receptor RXR-beta	1662118	RXR beta: a coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements.

Q9FGV1	ARFH_ARATH	Auxin response factor 8	10476078	Dimerization and DNA binding of auxin response factors.

O24310	EFTU_PEA	Elongation factor Tu, chloroplastic	15219860	A pea chloroplast translation elongation factor that is regulated by abiotic factors.

Q13304	GPR17_HUMAN	Uracil nucleotide/cysteinyl leukotriene receptor	8558062	New members of the chemokine receptor gene family.

P50623	UBC9_YEAST	SUMO-conjugating enzyme UBC9	7800043	Role of a ubiquitin-conjugating enzyme in degradation of S- and M- phase cyclins.

Q9JL27	FUT2_MOUSE	Galactoside 2-alpha-L-fucosyltransferase 2	11323419	Molecular cloning, genomic mapping, and expression of two secretor blood group alpha (1,2)fucosyltransferase genes differentially regulated in mouse uterine epithelium and gastrointestinal tract.

P47037	SMC3_YEAST	Structural maintenance of chromosomes protein 3	9335333	Cohesins: chromosomal proteins that prevent premature separation of sister chromatids.

Q6HA08	ASTL_HUMAN	Astacin-like metalloendopeptidase	15087446	Identification and characterization of human and mouse ovastacin, a novel metalloproteinase similar to hatching enzymes from arthropods, birds, amphibians, and fish.

P47924	RIBBA_ARATH	Riboflavin biosynthesis protein ribBA, chloroplastic	10783978	Biosynthesis of riboflavin in plants. The ribA gene of Arabidopsis thaliana specifies a bifunctional GTP cyclohydrolase II/3,4-dihydroxy- 2-butanone 4-phosphate synthase.

O95411	TIAF1_HUMAN	TGFB1-induced anti-apoptotic factor 1	9918798	Cloning and characterization of a novel transforming growth factor- beta1-induced TIAF1 protein that inhibits tumor necrosis factor cytotoxicity.

P54005	DIA1_YEAST	Protein DIA1	11063681	Genetic analysis reveals that FLO11 upregulation and cell polarization independently regulate invasive growth in Saccharomyces cerevisiae.

Q76HN1	HYAL1_RAT	Hyaluronidase-1	12397638	Expression of hyaluronan synthase 2 or hyaluronidase 1 differentially affect the growth rate of transplantable colon carcinoma cell tumors.

Q24318	TFDP_DROME	Transcription factor Dp	15545624	Identification of a Drosophila Myb-E2F2/RBF transcriptional repressor complex.

P15735	PHKG2_HUMAN	Phosphorylase b kinase gamma catalytic chain, testis/liver isoform	8896567	Mutations in the testis/liver isoform of the phosphorylase kinase gamma subunit (PHKG2) cause autosomal liver glycogenosis in the gsd rat and in humans.

Q9UHL9	GT2D1_HUMAN	General transcription factor II-I repeat domain-containing protein 1	10575229	Identification of GTF2IRD1, a putative transcription factor within the Williams-Beuren syndrome deletion at 7q11.23.

Q16720	AT2B3_HUMAN	Plasma membrane calcium-transporting ATPase 3	8765088	Primary structure of human plasma membrane Ca(2+)-ATPase isoform 3.

Q09175	KRP1_SCHPO	Dibasic-processing endoprotease	11115118	Identification of proteases with shared functions to the proprotein processing protease Krp1 in the fission yeast Schizosaccharomyces pombe.

Q96NU7	HUTI_HUMAN	Probable imidazolonepropionase	15221005	Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas.

Q9UTF8	UGO1_SCHPO	Mitochondrial fusion and transport protein ugo1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NFU0	FMR1_DROME	Fragile X mental retardation syndrome-related protein 1	11733059	Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function.

Q9UK32	KS6A6_HUMAN	Ribosomal protein S6 kinase alpha-6	10644430	A novel ribosomal S6-kinase (RSK4; RPS6KA6) is commonly deleted in patients with complex X-linked mental retardation.

P63330	PP2AA_MOUSE	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform	18084284	Unified mode of centromeric protection by shugoshin in mammalian oocytes and somatic cells.

Q8R5M8	CADM1_MOUSE	Cell adhesion molecule 1	12826663	Implications of nectin-like molecule- 2/IGSF4/RA175/SgIGSF/TSLC1/SynCAM1 in cell-cell adhesion and transmembrane protein localization in epithelial cells.

P20036	DPA1_HUMAN	HLA class II histocompatibility antigen, DP alpha 1 chain	2461352	Epitope recognition by a DP alpha chain-specific monoclonal antibody (DP11.1) is influenced by the interaction between the DP alpha chain and its polymorphic DP beta chain partner.

Q8L9T5	ATL2_ARATH	RING-H2 finger protein ATL2	10480382	Early elicitor induction in members of a novel multigene family coding for highly related RING-H2 proteins in Arabidopsis thaliana.

Q93971	TRPG_CAEEL	Transient receptor potential channel	11290424	The C. elegans gon-2 gene encodes a putative TRP cation channel protein required for mitotic cell cycle progression.

Q9EP80	PICK1_RAT	PRKCA-binding protein	11237868	Mitogen-stimulated TIS21 protein interacts with a protein-kinase- Calpha-binding protein rPICK1.

P0C1T0	MMEL1_RAT	Membrane metallo-endopeptidase-like 1	11964170	Cell-specific activity of neprilysin 2 isoforms and enzymic specificity compared with neprilysin.

Q8R4E9	CDT1_MOUSE	DNA replication factor Cdt1	11850834	Oncogenic potential of the DNA replication licensing protein CDT1.

Q12464	RUVB2_YEAST	RuvB-like protein 2	10952318	A chromatin remodelling complex involved in transcription and DNA processing.

Q9UT39	YIQ4_SCHPO	Uncharacterized WD repeat-containing protein C824.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P17706	PTN2_HUMAN	Tyrosine-protein phosphatase non-receptor type 2	2546150	cDNA isolated from a human T-cell library encodes a member of the protein-tyrosine-phosphatase family.

Q8R534	ADM1B_MOUSE	Disintegrin and metalloproteinase domain-containing protein 1b	12095680	The ADAM1a and ADAM1b genes, instead of the ADAM1 (fertilin alpha) gene, are localized on mouse chromosome 5.

P07713	DECA_DROME	Protein decapentaplegic	10903186	sog and dpp exert opposing maternal functions to modify toll signaling and pattern the dorsoventral axis of the Drosophila embryo.

Q16586	SGCA_HUMAN	Alpha-sarcoglycan	7937874	Human adhalin is alternatively spliced and the gene is on chromosome 17q21.

O95394	AGM1_HUMAN	Phosphoacetylglucosamine mutase	11004509	Functional cloning and mutational analysis of the human cDNA for phosphoacetylglucosamine mutase: identification of the amino acid residues essential for the catalysis.

P51398	RT29_HUMAN	28S ribosomal protein S29, mitochondrial	7499268	Isolation of DAP3, a novel mediator of interferon-gamma-induced cell death.

O00154	BACH_HUMAN	Cytosolic acyl coenzyme A thioester hydrolase	10578051	Purification, molecular cloning, and genomic organization of human brain long-chain acyl-CoA hydrolase.

Q9W1R5	VIR_DROME	Protein virilizer	10101174	Trans-acting factors required for inclusion of regulated exons in the Ultrabithorax mRNAs of Drosophila melanogaster.

Q07949	PSR2_YEAST	Probable phosphatase PSR2	12090248	Yeast Whi2 and Psr1-phosphatase form a complex and regulate STRE- mediated gene expression.

Q24046	ATPB1_DROME	Sodium/potassium-transporting ATPase subunit beta-1	17606467	A novel family of transmembrane proteins interacting with beta subunits of the Na,K-ATPase.

Q9R0H5	K2C71_MOUSE	Keratin, type II cytoskeletal 71	14573483	A small deletion hotspot in the type II keratin gene mK6irs1/Krt2-6g on mouse chromosome 15, a candidate for causing the wavy hair of the caracul (Ca) mutation.

Q9R803	SSED_SALTY	Secreted effector protein sseD	11159962	Salmonella pathogenicity island 2-encoded proteins SseC and SseD are essential for virulence and are substrates of the type III secretion system.

Q61301	CTNA2_MOUSE	Catenin alpha-2	12089526	Deletion in Catna2, encoding alpha N-catenin, causes cerebellar and hippocampal lamination defects and impaired startle modulation.

A5LGM7	TRET1_POLVA	Facilitated trehalose transporter Tret1	20035867	The trehalose transporter 1 gene sequence is conserved in insects and encodes proteins with different kinetic properties involved in trehalose import into peripheral tissues.

Q9WTK3	GPAA1_MOUSE	Glycosylphosphatidylinositol anchor attachment 1 protein	10393431	Human and mouse GPAA1 (glycosylphosphatidylinositol anchor attachment 1) genes: genomic structures, chromosome loci and the presence of a minor class intron.

Q6PIY7	GLD2_HUMAN	Poly(A) RNA polymerase GLD2	15070731	Mammalian GLD-2 homologs are poly(A) polymerases.

O42569	SOX2_XENLA	Transcription factor Sox-2	10648237	Requirement of Sox2-mediated signaling for differentiation of early Xenopus neuroectoderm.

Q0VDQ9	FEZF1_MOUSE	Fez family zinc finger protein 1	16540508	Zinc-finger gene Fez in the olfactory sensory neurons regulates development of the olfactory bulb non-cell-autonomously.

P10566	MRS3_YEAST	Mitochondrial RNA-splicing protein MRS3	2448588	Nuclear suppression of a mitochondrial RNA splice defect: nucleotide sequence and disruption of the MRS3 gene.

Q9LQ68	GH34_ARATH	Indole-3-acetic acid-amido synthetase GH3.4	15659623	Characterization of an Arabidopsis enzyme family that conjugates amino acids to indole-3-acetic acid.

P84641	CIRC_CHAPA	Circulin-C	10691702	New circulin macrocyclic polypeptides from Chassalia parvifolia.

Q62649	NNAT_RAT	Neuronatin	8024565	Molecular cloning of a novel mRNA (neuronatin) that is highly expressed in neonatal mammalian brain.

P43557	FMP32_YEAST	Protein FMP32, mitochondrial	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Q9BSQ5	CCM2_HUMAN	Malcavernin	20489202	Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity.

Q14192	FHL2_HUMAN	Four and a half LIM domains protein 2	9150430	Subtractive cloning and characterization of DRAL, a novel LIM-domain protein down-regulated in rhabdomyosarcoma.

Q9VHA0	SCM_DROME	Polycomb protein Scm	8625848	The Drosophila polycomb group gene Sex comb on midleg (Scm) encodes a zinc finger protein with similarity to polyhomeotic protein.

P13663	DHAS_YEAST	Aspartate-semialdehyde dehydrogenase	2570346	Structure of the HOM2 gene of Saccharomyces cerevisiae and regulation of its expression.

Q9JJT9	PHAX_MOUSE	Phosphorylated adapter RNA export protein	10786834	PHAX, a mediator of U snRNA nuclear export whose activity is regulated by phosphorylation.

Q96BU1	S1PBP_HUMAN	S100P-binding protein	15632002	Expression of S100P and its novel binding partner S100PBPR in early pancreatic cancer.

Q9NYC9	DYH9_HUMAN	Dynein heavy chain 9, axonemal	11104725	Characterization of an axonemal dynein heavy chain expressed early in airway epithelial ciliogenesis.

Q9SGS4	CDSP_ARATH	Thioredoxin-like protein CDSP32, chloroplastic	12084836	The plastidic 2-cysteine peroxiredoxin is a target for a thioredoxin involved in the protection of the photosynthetic apparatus against oxidative damage.

P32641	RAD24_YEAST	Checkpoint protein RAD24	12604797	Yeast Rad17/Mec3/Ddc1: a sliding clamp for the DNA damage checkpoint.

P40344	ATG3_YEAST	Autophagy-related protein 3	11100732	A ubiquitin-like system mediates protein lipidation.

P40014	SPC25_YEAST	Kinetochore protein SPC25	11179222	The budding yeast proteins Spc24p and Spc25p interact with Ndc80p and Nuf2p at the kinetochore and are important for kinetochore clustering and checkpoint control.

P23292	KC12_YEAST	Casein kinase I homolog 2	1729698	Yeast casein kinase I homologues: an essential gene pair.

Q9U489	LIN41_CAEEL	Protein lin-41	10882102	The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor.

Q8K430	KLH17_RAT	Kelch-like protein 17	12063253	Actinfilin, a brain-specific actin-binding protein in postsynaptic density.

Q9P6J1	ACEB_SCHPO	Mitochondrial 2-methylisocitrate lyase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O14746	TERT_HUMAN	Telomerase reverse transcriptase	9288757	hEST2, the putative human telomerase catalytic subunit gene, is up- regulated in tumor cells and during immortalization.

Q60749	KHDR1_MOUSE	KH domain-containing, RNA-binding, signal transduction-associated protein 1	12496368	Physical and functional interaction between the transcriptional cofactor CBP and the KH domain protein Sam68.

Q94IN5	PNO_EUGGR	Pyruvate dehydrogenase [NADP+], mitochondrial	11319255	Pyruvate: NADP oxidoreductase from the mitochondrion of Euglena gracilis and from the apicomplexan Cryptosporidium parvum: a biochemical relic linking pyruvate metabolism in mitochondriate and amitochondriate protists.

Q9UPV9	TRAK1_HUMAN	Trafficking kinesin-binding protein 1	15644324	GRIF-1 and OIP106, members of a novel gene family of coiled-coil domain proteins: association in vivo and in vitro with kinesin.

P38398	BRCA1_HUMAN	Breast cancer type 1 susceptibility protein	11301010	BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function.

P38137	FAT2_YEAST	Peroxisomal-coenzyme A synthetase	8841414	Identification of a yeast peroxisomal member of the family of AMP- binding proteins.

P53744	BIO5_YEAST	7-keto 8-aminopelargonic acid transporter	10333520	Characterization of the biotin biosynthesis pathway in Saccharomyces cerevisiae and evidence for a cluster containing BIO5, a novel gene involved in vitamer uptake.

Q9UTI7	TYSY_SCHPO	Probable thymidylate synthase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12406	ARP7_YEAST	Actin-related protein 7	10025404	Histone octamer transfer by a chromatin-remodeling complex.

P47090	YJY5_YEAST	Uncharacterized endoplasmic reticulum membrane protein YJR015W	14562095	Global analysis of protein localization in budding yeast.

Q7TPD6	RAVR2_MOUSE	Ribonucleoprotein PTB-binding 2	16051233	Raver2, a new member of the hnRNP family.

P18206	VINC_HUMAN	Vinculin	2116004	Complete sequence of human vinculin and assignment of the gene to chromosome 10.

P46962	CTK2_YEAST	CTD kinase subunit beta	7565723	The yeast carboxyl-terminal repeat domain kinase CTDK-I is a divergent cyclin-cyclin-dependent kinase complex.

P16144	ITB4_HUMAN	Integrin beta-4	2311577	Amino acid sequence of a novel integrin beta 4 subunit and primary expression of the mRNA in epithelial cells.

Q13562	NDF1_HUMAN	Neurogenic differentiation factor 1	10545951	Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus.

O15943	CADN_DROME	Neural-cadherin	9247265	Axon patterning requires DN-cadherin, a novel neuronal adhesion receptor, in the Drosophila embryonic CNS.

O08575	EYA2_MOUSE	Eyes absent homolog 2	14628052	Eyes absent represents a class of protein tyrosine phosphatases.

P35456	UPAR_MOUSE	Urokinase plasminogen activator surface receptor	19667118	Sushi repeat protein X-linked 2, a novel mediator of angiogenesis.

Q1MTQ0	BRL1_SCHPO	E3 ubiquitin-protein ligase brl1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P14920	OXDA_HUMAN	D-amino-acid oxidase	1356107	Molecular cloning and chromosomal localization of a human gene encoding D-amino-acid oxidase.

P53898	NSG2_YEAST	Protein NSG2	16270032	INSIG: a broadly conserved transmembrane chaperone for sterol-sensing domain proteins.

O74456	PEF1_SCHPO	Serine/threonine-protein kinase pef1	10982385	A pcl-like cyclin activates the Res2p-Cdc10p cell cycle 'start' transcriptional factor complex in fission yeast.

O81445	CNBL1_ARATH	Calcineurin B-like protein 1	14730064	Calcium sensors and their interacting protein kinases: genomics of the Arabidopsis and rice CBL-CIPK signaling networks.

P07948	LYN_HUMAN	Tyrosine-protein kinase Lyn	10891478	Role for Lyn tyrosine kinase as a regulator of stress-activated protein kinase activity in response to DNA damage.

Q08496	DIA2_YEAST	Protein DIA2	16421250	The F-box protein Dia2 regulates DNA replication.

Q9I927	FUCL5_ANGJA	Fucolectin-5	10924498	Multiplicity, structures, and endocrine and exocrine natures of eel fucose-binding lectins.

Q9VBQ9	MED28_DROME	Mediator of RNA polymerase II transcription subunit 28	12021283	Novel Mediator proteins of the small Mediator complex in Drosophila SL2 cells.

O93507	TAL1_DANRE	T-cell acute lymphocytic leukemia protein 1 homolog	17722983	Early endocardial morphogenesis requires Scl/Tal1.

O95182	NDUA7_HUMAN	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7	9878551	cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed.

P47068	BBC1_YEAST	Myosin tail region-interacting protein MTI1	11901111	The novel adaptor protein, Mti1p, and Vrp1p, a homolog of Wiskott- Aldrich syndrome protein-interacting protein (WIP), may antagonistically regulate type I myosins in Saccharomyces cerevisiae.

Q4W815	EPOR_XENLA	Erythropoietin receptor	16091591	Expression of erythropoietin receptor-like molecule in Xenopus laevis and erythrocytopenia upon administration of its recombinant soluble form.

Q9VKM6	VPS72_DROME	Vacuolar protein sorting-associated protein 72 homolog	15528408	Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions.

P36150	SUMT_YEAST	Uroporphyrinogen-III C-methyltransferase	9003798	Siroheme biosynthesis in Saccharomyces cerevisiae requires the products of both the MET1 and MET8 genes.

P46100	ATRX_HUMAN	Transcriptional regulator ATRX	15882967	The mammalian heterochromatin protein 1 binds diverse nuclear proteins through a common motif that targets the chromoshadow domain.

O88552	CLD2_MOUSE	Claudin-2	10562289	Manner of interaction of heterogeneous claudin species within and between tight junction strands.

Q9NXR7	BRE_HUMAN	BRCA1-A complex subunit BRE	19261749	NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control.

Q922Q6	ABHEA_MOUSE	Abhydrolase domain-containing protein 14A	14667578	Dorz1, a novel gene expressed in differentiating cerebellar granule neurons, is down-regulated in Zic1-deficient mouse.

P56568	RIP1_LUFCY	Ribosome-inactivating protein luffin P1	12948831	Purification and characterization of Luffin P1, a ribosome- inactivating peptide from the seeds of Luffa cylindrica.

O94742	SEM1_YEAST	26S proteasome complex subunit SEM1	15117943	Sem1p is a novel subunit of the 26S proteasome from Saccharomyces cerevisiae.

P40047	ALDH5_YEAST	Aldehyde dehydrogenase 5, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q7G8V2	ARR15_ARATH	Two-component response regulator ARR15	12941880	The type-A response regulator, ARR15, acts as a negative regulator in the cytokinin-mediated signal transduction in Arabidopsis thaliana.

Q96WV0	UREG_SCHPO	Uncharacterized urease accessory protein ureG-like	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Z0Z5	S13A3_RAT	Solute carrier family 13 member 3	10207168	Molecular and functional analysis of SDCT2, a novel rat sodium- dependent dicarboxylate transporter.

Q9Y6M7	S4A7_HUMAN	Sodium bicarbonate cotransporter 3	10347222	Cloning, tissue distribution, genomic organization, and functional characterization of NBC3, a new member of the sodium bicarbonate cotransporter family.

P29066	ARRB1_RAT	Beta-arrestin-1	1517224	Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family.

P30405	PPIF_HUMAN	Peptidyl-prolyl cis-trans isomerase F, mitochondrial	1744118	The cyclophilin multigene family of peptidyl-prolyl isomerases. Characterization of three separate human isoforms.

Q91VN1	ZNF24_MOUSE	Zinc finger protein 24	20080941	ZFP191 is required by oligodendrocytes for CNS myelination.

Q495M9	USH1G_HUMAN	Usher syndrome type-1G protein	12588794	Usher syndrome type I G (USH1G) is caused by mutations in the gene encoding SANS, a protein that associates with the USH1C protein, harmonin.

Q0WPH8	NEK5_ARATH	Serine/threonine-protein kinase Nek5	17971038	Armadillo repeat-containing kinesins and a NIMA-related kinase are required for epidermal-cell morphogenesis in Arabidopsis.

Q75RY2	PAIR1_ORYSJ	Protein PAIR1	15031413	The novel gene HOMOLOGOUS PAIRING ABERRATION IN RICE MEIOSIS1 of rice encodes a putative coiled-coil protein required for homologous chromosome pairing in meiosis.

Q9Y5P2	CSAG2_HUMAN	Chondrosarcoma-associated gene 2/3 protein	10095106	TRAG-3, a novel gene, isolated from a taxol-resistant ovarian carcinoma cell line.

Q16363	LAMA4_HUMAN	Laminin subunit alpha-4	7959779	Localization of the gene (LAMA4) to chromosome 6q21 and isolation of a partial cDNA encoding a variant laminin A chain.

Q9BWF2	TRAIP_HUMAN	TRAF-interacting protein	9104814	TRAF-interacting protein (TRIP): a novel component of the tumor necrosis factor receptor (TNFR)- and CD30-TRAF signaling complexes that inhibits TRAF2-mediated NF-kappaB activation.

P62942	FKB1A_HUMAN	Peptidyl-prolyl cis-trans isomerase FKBP1A	1696686	Molecular cloning and overexpression of the human FK506-binding protein FKBP.

Q7G193	ALDO1_ARATH	Aldehyde oxidase 1	10739959	Functional expression of two Arabidopsis aldehyde oxidases in the yeast Pichia pastoris.

P38316	ATG12_YEAST	Ubiquitin-like protein ATG12	10508157	Apg10p, a novel protein-conjugating enzyme essential for autophagy in yeast.

P39748	FEN1_HUMAN	Flap endonuclease 1	11986308	Arginine residues 47 and 70 of human flap endonuclease-1 are involved in DNA substrate interactions and cleavage site determination.

P63173	RL38_HUMAN	60S ribosomal protein L38	9375793	Primary sequence of the human, lysine-rich, ribosomal protein RPL38 and detection of an unusual RPL38 processed pseudogene in the promoter region of the type-1 angiotensin II receptor gene.

P31129	YDEH_ECOLI	Diguanylate cyclase YdeH	18713317	The RNA binding protein CsrA controls cyclic di-GMP metabolism by directly regulating the expression of GGDEF proteins.

P04085	PDGFA_HUMAN	Platelet-derived growth factor subunit A	3754619	cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines.

O70394	I27RA_MOUSE	Interleukin-27 receptor subunit alpha	11057672	Development of Th1-type immune responses requires the type I cytokine receptor TCCR.

Q04206	TF65_HUMAN	Transcription factor p65	10521409	IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain.

Q9JI13	SAS10_MOUSE	Something about silencing protein 10	11404095	Cloning and expression pattern of a novel PEBP2 beta-binding protein (charged amino acid rich leucine zipper-1[Crl-1]) in the mouse.

Q9WUK6	ZN238_MOUSE	Zinc finger protein 238	20059953	A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.

Q5BAU9	PELA_EMENI	Pectin lyase A	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

Q9P7Z6	YJIA_SCHPO	Uncharacterized protein C5E4.10c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q10282	GBB_SCHPO	Guanine nucleotide-binding protein subunit beta	10747045	The fission yeast git5 gene encodes a gbeta subunit required for glucose-triggered adenylate cyclase activation.

Q96PK6	RBM14_HUMAN	RNA-binding protein 14	15919756	Synovial sarcoma translocation (SYT) encodes a nuclear receptor coactivator.

Q8R0V5	I23O2_MOUSE	Indoleamine 2,3-dioxygenase 2	17499941	Characterization of an indoleamine 2,3-dioxygenase-like protein found in humans and mice.

P76343	YEDZ_ECOLI	Sulfoxide reductase heme-binding subunit yedZ	11867724	Rapid topology mapping of Escherichia coli inner-membrane proteins by prediction and PhoA/GFP fusion analysis.

P15538	C11B1_HUMAN	Cytochrome P450 11B1, mitochondrial	2022736	A mutation in CYP11B1 (Arg-448-->His) associated with steroid 11 beta-hydroxylase deficiency in Jews of Moroccan origin.

Q91X34	BAAT_MOUSE	Bile acid-CoA:amino acid N-acyltransferase	9215542	Cloning, expression, and chromosomal localization of mouse liver bile acid CoA:amino acid N-acyltransferase.

O49725	PUP10_ARATH	Probable purine permease 10	10662864	A new family of high-affinity transporters for adenine, cytosine, and purine derivatives in Arabidopsis.

Q8K4Y5	LGI1_RAT	Leucine-rich glioma-inactivated protein 1	16990550	Epilepsy-related ligand/receptor complex LGI1 and ADAM22 regulate synaptic transmission.

O94363	RHB1_SCHPO	GTP-binding protein rhb1	10835385	Loss of Rhb1, a Rheb-related GTPase in fission yeast, causes growth arrest with a terminal phenotype similar to that caused by nitrogen starvation.

O21033	RM14_DICDI	60S ribosomal protein L14, mitochondrial	9560439	A ribosomal protein gene cluster is encoded in the mitochondrial DNA of Dictyostelium discoideum: UGA termination codons and similarity of gene order to Acanthamoeba castellanii.

Q9USQ6	SYJ2_SCHPO	Inositol-1,4,5-trisphosphate 5-phosphatase 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q92530	PSMF1_HUMAN	Proteasome inhibitor PI31 subunit	10764772	cDNA cloning, expression, and functional characterization of PI31, a proline-rich inhibitor of the proteasome.

Q8TEY7	UBP33_HUMAN	Ubiquitin carboxyl-terminal hydrolase 33	17766394	The solution structure of the ZnF UBP domain of USP33/VDU1.

P70169	DOC2B_MOUSE	Double C2-like domain-containing protein beta	17548353	Doc2beta is a novel Munc18c-interacting partner and positive effector of syntaxin 4-mediated exocytosis.

P25089	FPR3_HUMAN	N-formyl peptide receptor 3	8198572	Differential expression of members of the N-formylpeptide receptor gene cluster in human phagocytes.

Q9HDY7	YK12_SCHPO	Uncharacterized protein PB1A10.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P42768	WASP_HUMAN	Wiskott-Aldrich syndrome protein	12769847	Phosphorylation of the WASP-VCA domain increases its affinity for the Arp2/3 complex and enhances actin polymerization by WASP.

P46937	YAP1_HUMAN	Yorkie homolog	18579750	TEAD mediates YAP-dependent gene induction and growth control.

Q9NZH6	IL1F7_HUMAN	Interleukin-1 family member 7	10625660	Four new members expand the IL-1 superfamily.

Q9W1U4	KI59C_DROME	Kinesin-like protein Klp59C	14681690	Two mitotic kinesins cooperate to drive sister chromatid separation during anaphase.

P22681	CBL_HUMAN	E3 ubiquitin-protein ligase CBL	2030914	The sequences of the human and mouse c-cbl proto-oncogenes show v-cbl was generated by a large truncation encompassing a proline-rich domain and a leucine zipper-like motif.

O94374	IMA2_SCHPO	Importin subunit alpha-2	15937127	The fission yeast Schizosaccharomyces pombe has two importin-alpha proteins, Imp1p and Cut15p, which have common and unique functions in nucleocytoplasmic transport and cell cycle progression.

Q9UTN6	SNF21_SCHPO	Chromatin structure-remodeling complex subunit snf21	18622392	Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast.

Q9U6M0	ECSIT_DROME	Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial	10465784	ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway.

P24941	CDK2_HUMAN	Cell division protein kinase 2	15611625	Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins.

P0ABN1	KDGL_ECOLI	Diacylglycerol kinase	8071224	Membrane topology of Escherichia coli diacylglycerol kinase.

O94347	YCB3_SCHPO	Uncharacterized protein C61.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P38398	BRCA1_HUMAN	Breast cancer type 1 susceptibility protein	20351172	The UBXN1 protein associates with autoubiquitinated forms of the BRCA1 tumor suppressor and inhibits its enzymatic function.

O61967	LAP1_CAEEL	Protein lap1	15063180	The apical disposition of the Caenorhabditis elegans intestinal terminal web is maintained by LET-413.

Q9S9N4	MRS21_ARATH	Magnesium transporter MRS2-1	19966073	A root-expressed magnesium transporter of the MRS2/MGT gene family in Arabidopsis thaliana allows for growth in low-Mg2+ environments.

Q8RXX9	ATL6_ARATH	E3 ubiquitin-protein ligase ATL6	15644464	Functional analysis of the RING-type ubiquitin ligase family of Arabidopsis.

Q9BXX0	EMIL2_HUMAN	EMILIN-2	11278945	Isolation and characterization of EMILIN-2, a new component of the growing EMILINs family and a member of the EMI domain-containing superfamily.

Q6TMK3	HSP88_DICDI	Heat shock protein 88	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q9C5C8	MSRB2_ARATH	Peptide methionine sulfoxide reductase B2, chloroplastic	17031545	Plant methionine sulfoxide reductase A and B multigenic families.

Q91VE0	S27A4_MOUSE	Long-chain fatty acid transport protein 4	10518211	Identification of the major intestinal fatty acid transport protein.

O88508	DNM3A_MOUSE	DNA (cytosine-5)-methyltransferase 3A	11399089	Enzymatic properties of recombinant Dnmt3a DNA methyltransferase from mouse: the enzyme modifies DNA in a non-processive manner and also methylates non-CpG correction sites.

O43272	PROD_HUMAN	Proline dehydrogenase, mitochondrial	9385373	A human homologue of the Drosophila melanogaster sluggish-A (proline oxidase) gene maps to 22q11.2, and is a candidate gene for type-I hyperprolinaemia.

Q9UKG1	DP13A_HUMAN	DCC-interacting protein 13-alpha	10490823	Identification of a chromosome 3p14.3-21.1 gene, APPL, encoding an adaptor molecule that interacts with the oncoprotein-serine/threonine kinase AKT2.

Q8TEY7	UBP33_HUMAN	Ubiquitin carboxyl-terminal hydrolase 33	19118533	Human selenium binding protein-1 (hSP56) interacts with VDU1 in a selenium-dependent manner.

Q6NVG5	MREG_MOUSE	Melanoregulin	15550542	dsu functions in a MYO5A-independent pathway to suppress the coat color of dilute mice.

P43571	BST1_YEAST	GPI inositol-deacylase	14734546	Inositol deacylation of glycosylphosphatidylinositol-anchored proteins is mediated by mammalian PGAP1 and yeast Bst1p.

P37042	GON1_CHICK	Progonadoliberin-1	7050119	Structure of chicken hypothalamic luteinizing hormone-releasing hormone. II. Isolation and characterization.

Q08278	MED7_YEAST	Mediator of RNA polymerase II transcription subunit 7	9420330	The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain.

Q09196	MLR4_SCHPO	Myosin regulatory light chain cdc4	11087750	Structure of Cdc4p, a contractile ring protein essential for cytokinesis in Schizosaccharomyces pombe.

P32569	MED17_YEAST	Mediator of RNA polymerase II transcription subunit 17	16885025	Head module control of mediator interactions.

Q9VM71	XRN2_DROME	5'-3' exoribonuclease 2 homolog	17363252	Cutoff and aubergine mutations result in retrotransposon upregulation and checkpoint activation in Drosophila.

A1Z7G7	LPHN_DROME	Latrophilin Cirl	10798391	A genome-wide search for synaptic vesicle cycle proteins in Drosophila.

P97943	SCRB1_RAT	Scavenger receptor class B member 1	9177301	Cloning, characterization, and cellular distribution of rat scavenger receptor class B type I (SRBI) in the ovary.

P79007	HAP5_SCHPO	Transcriptional activator hap5	9372932	The Saccharomyces cerevisiae Hap5p homolog from fission yeast reveals two conserved domains that are essential for assembly of heterotetrameric CCAAT-binding factor.

Q9NLA3	ANO39_ASTPE	Nucleoplasmin-like protein ANO39	10632699	Molecular characterization of a novel nucleolar protein in starfish oocytes which is phosphorylated before and during oocyte maturation.

Q99743	NPAS2_HUMAN	Neuronal PAS domain-containing protein 2	9012850	Molecular characterization of two mammalian bHLH-PAS domain proteins selectively expressed in the central nervous system.

Q9Y223	GLCNE_HUMAN	Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase	10334995	UDP-GlcNAc 2-epimerase: a regulator of cell surface sialylation.

O74837	PMP31_SCHPO	Plasma membrane proteolipid 31	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P54780	RL15B_YEAST	60S ribosomal protein L15-B	6814480	Isolation of seventeen proteins and amino-terminal amino acid sequences of eight proteins from cytoplasmic ribosomes of yeast.

P46527	CDN1B_HUMAN	Cyclin-dependent kinase inhibitor 1B	17254966	Cdk-inhibitory activity and stability of p27Kip1 are directly regulated by oncogenic tyrosine kinases.

Q12988	HSPB3_HUMAN	Heat shock protein beta-3	8972725	Isolation and characterization of a human heart cDNA encoding a new member of the small heat shock protein family -- HSPL27.

P53059	MNT2_YEAST	Alpha-1,3-mannosyltransferase MNT2	10521541	Mnt2p and Mnt3p of Saccharomyces cerevisiae are members of the Mnn1p family of alpha-1,3-mannosyltransferases responsible for adding the terminal mannose residues of O-linked oligosaccharides.

Q09624	LOV1_CAEEL	Location of vulva defective 1	10517638	A polycystic kidney-disease gene homologue required for male mating behaviour in C. elegans.

P76316	DCYD_ECOLI	D-cysteine desulfhydrase	11527960	Role of D-cysteine desulfhydrase in the adaptation of Escherichia coli to D-cysteine.

Q6BCL1	PRAM_MOUSE	PML-RARA-regulated adapter molecule 1	15572693	PRAM-1 is required for optimal integrin-dependent neutrophil function.

Q8LJT8	TKI1_ARATH	TSL-kinase interacting protein 1	15047893	TOUSLED kinase activity oscillates during the cell cycle and interacts with chromatin regulators.

P40487	DPH1_YEAST	Diphthamide biosynthesis protein 1	14562095	Global analysis of protein localization in budding yeast.

O60244	MED14_HUMAN	Mediator of RNA polymerase II transcription subunit 14	10235266	Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex.

P83308	FARP_CHICK	FMRFamide-like neuropeptide	6137771	A novel active pentapeptide from chicken brain identified by antibodies to FMRFamide.

Q08949	DDC1_YEAST	DNA damage checkpoint protein 1	16169844	The 9-1-1 checkpoint clamp physically interacts with polzeta and is partially required for spontaneous polzeta-dependent mutagenesis in Saccharomyces cerevisiae.

Q62048	PEA15_MOUSE	Astrocytic phosphoprotein PEA-15	8662970	The major astrocytic phosphoprotein PEA-15 is encoded by two mRNAs conserved on their full length in mouse and human.

Q9HCG8	CWC22_HUMAN	Pre-mRNA-splicing factor CWC22 homolog	11991638	Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.

Q5T160	SYRM_HUMAN	Probable arginyl-tRNA synthetase, mitochondrial	17847012	Deleterious mutation in the mitochondrial arginyl-transfer RNA synthetase gene is associated with pontocerebellar hypoplasia.

Q09847	NU146_SCHPO	Nucleoporin nup146	15116432	Identification of genes encoding putative nucleoporins and transport factors in the fission yeast Schizosaccharomyces pombe: a deletion analysis.

Q07980	MLH2_YEAST	DNA mismatch repair protein MLH2	10570173	Functional specificity of MutL homologs in yeast: evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction.

Q9FMY1	C86B1_ARATH	Cytochrome P450 86B1	19525321	CYP86B1 is required for very long chain omega-hydroxyacid and alpha, omega -dicarboxylic acid synthesis in root and seed suberin polyester.

Q0IIF7	UBP14_BOVIN	Ubiquitin carboxyl-terminal hydrolase 14	18162577	Relative structural and functional roles of multiple deubiquitylating proteins associated with mammalian 26S proteasome.

Q54YA0	ACLY_DICDI	Probable ATP-citrate synthase	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

O13710	SMC5_SCHPO	Structural maintenance of chromosomes protein 5	15331764	Nse1, Nse2, and a novel subunit of the Smc5-Smc6 complex, Nse3, play a crucial role in meiosis.

P53128	MTHR2_YEAST	Methylenetetrahydrofolate reductase 2	10600168	Saccharomyces cerevisiae expresses two genes encoding isozymes of methylenetetrahydrofolate reductase.

Q9Y243	AKT3_HUMAN	RAC-gamma serine/threonine-protein kinase	10092583	A human protein kinase B gamma with regulatory phosphorylation sites in the activation loop and in the C-terminal hydrophobic domain.

Q90416	RXRGA_DANRE	Retinoic acid receptor RXR-gamma-A	7565671	New retinoid X receptor subtypes in zebra fish (Danio rerio) differentially modulate transcription and do not bind 9-cis retinoic acid.

Q8WZA1	PMGT1_HUMAN	Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1	11709191	Muscular dystrophy and neuronal migration disorder caused by mutations in a glycosyltransferase, POMGnT1.

O88450	DEAF1_RAT	Deformed epidermal autoregulatory factor 1 homolog	9773984	Characterization of a nuclear deformed epidermal autoregulatory factor-1 (DEAF-1)-related (NUDR) transcriptional regulator protein.

Q967D7	TUTL_DROME	Protein turtle	11312296	A novel member of the Ig superfamily, turtle, is a CNS-specific protein required for coordinated motor control.

P42846	KRI1_YEAST	Protein KRI1	11027267	Yeast Krr1p physically and functionally interacts with a novel essential Kri1p, and both proteins are required for 40S ribosome biogenesis in the nucleolus.

Q86A77	VATD_DICDI	V-type proton ATPase subunit D	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q9UT86	APC11_SCHPO	Anaphase-promoting complex subunit 11	12477395	Proteomics analysis identifies new components of the fission and budding yeast anaphase-promoting complexes.

Q505B8	SYCE2_MOUSE	Synaptonemal complex central element protein 2	15944401	Two novel proteins recruited by synaptonemal complex protein 1 (SYCP1) are at the center of meiosis.

Q9UBQ5	EIF3K_HUMAN	Eukaryotic translation initiation factor 3 subunit K	17581632	Reconstitution reveals the functional core of mammalian eIF3.

O13692	GAS5_SCHPO	1,3-beta-glucanosyltransferase gas5	17230583	Mass spectrometric identification of covalently bound cell wall proteins from the fission yeast Schizosaccharomyces pombe.

Q9NRS6	SNX15_HUMAN	Sorting nexin-15	11085978	Identification and characterization of snx15, a novel sorting nexin involved in protein trafficking.

A8WCF8	TPRGL_RAT	Tumor protein p63-regulated gene 1-like protein	17869247	Mover is a novel vertebrate-specific presynaptic protein with differential distribution at subsets of CNS synapses.

Q15366	PCBP2_HUMAN	Poly(rC)-binding protein 2	7607214	Characterisation of two major cellular poly(rC)-binding human proteins, each containing three K-homologous (KH) domains.

O74539	MAK3_SCHPO	Peroxide stress-activated histidine kinase mak3	11758939	Genetic analysis of the His-to-Asp phosphorelay implicated in mitotic cell cycle control: involvement of histidine-kinase genes of Schizosaccharomyces pombe.

Q07444	NKG2E_HUMAN	NKG2-E type II integral membrane protein	9683661	The genomic organization of NKG2C, E, F, and D receptor genes in the human natural killer gene complex.

P53855	ATG2_YEAST	Autophagy-related protein 2	8224160	Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae.

P38935	SMBP2_HUMAN	DNA-binding protein SMUBP-2	19299493	Biochemical and genetic evidence for a role of IGHMBP2 in the translational machinery.

P16455	MGMT_HUMAN	Methylated-DNA--protein-cysteine methyltransferase	2405387	Isolation and structural characterization of a cDNA clone encoding the human DNA repair protein for O6-alkylguanine.

Q04206	TF65_HUMAN	Transcription factor p65	12628924	Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1).

P32860	NFU1_YEAST	NifU-like protein, mitochondrial	10468587	Evidence for a conserved system for iron metabolism in the mitochondria of Saccharomyces cerevisiae.

P33749	MSN4_YEAST	Zinc finger protein MSN4	12732613	Oscillatory nucleocytoplasmic shuttling of the general stress response transcriptional activators Msn2 and Msn4 in Saccharomyces cerevisiae.

P48450	ERG7_RAT	Lanosterol synthase	7568116	Molecular cloning, characterization, and functional expression of rat oxidosqualene cyclase cDNA.

O70240	AXN2_RAT	Axin-2	9566905	Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3beta and beta-catenin and inhibits axis formation of Xenopus embryos.

Q9WVB3	TLE6_MOUSE	Transducin-like enhancer protein 6	18804437	A subcortical maternal complex essential for preimplantation mouse embryogenesis.

P85102	AFP_CULCO	Antifungal protein	16530884	Psc-AFP, an antifungal protein with trypsin inhibitor activity from Psoralea corylifolia seeds.

Q8ND76	CCNY_HUMAN	Cyclin-Y	19524571	Cyclin Y, a novel membrane-associated cyclin, interacts with PFTK1.

O88516	DLL3_MOUSE	Delta-like protein 3	9272948	Mouse Dll3: a novel divergent Delta gene which may complement the function of other Delta homologues during early pattern formation in the mouse embryo.

P30989	NTR1_HUMAN	Neurotensin receptor type 1	8381365	Cloning and expression of a complementary DNA encoding a high affinity human neurotensin receptor.

O96014	WNT11_HUMAN	Protein Wnt-11	9757009	Isolation, characterisation and embryonic expression of WNT11, a gene which maps to 11q13.5 and has possible roles in the development of skeleton, kidney and lung.

Q21227	APR1_CAEEL	Adenomatous polyposis coli protein-related protein 1	17276345	Cortical beta-catenin and APC regulate asymmetric nuclear beta- catenin localization during asymmetric cell division in C. elegans.

Q9H427	KCNKF_HUMAN	Potassium channel subfamily K member 15	11749039	Expression pattern in brain of TASK-1, TASK-3, and a tandem pore domain K(+) channel subunit, TASK-5, associated with the central auditory nervous system.

Q9UNQ0	ABCG2_HUMAN	ATP-binding cassette sub-family G member 2	9850061	A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance.

Q61025	IFT20_MOUSE	Intraflagellar transport protein 20 homolog	15337773	Pericentrin forms a complex with intraflagellar transport proteins and polycystin-2 and is required for primary cilia assembly.

Q86JF2	LVSB_DICDI	BEACH domain-containing protein lvsB	17606989	A LYST/beige homolog is involved in biogenesis of Dictyostelium secretory lysosomes.

O08623	SQSTM_RAT	Sequestosome-1	9177193	Interaction of protein kinase C zeta with ZIP, a novel protein kinase C-binding protein.

P47082	AVT1_YEAST	Vacuolar amino acid transporter 1	11274162	A family of yeast proteins mediating bidirectional vacuolar amino acid transport.

Q9SU58	PMA4_ARATH	ATPase 4, plasma membrane-type	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

P13164	IFM1_HUMAN	Interferon-induced transmembrane protein 1	7559564	Expression cloning of an interferon-inducible 17-kDa membrane protein implicated in the control of cell growth.

Q18007	ACM1_CAEEL	Probable muscarinic acetylcholine receptor gar-1	11032868	Characterization of GAR-2, a novel G protein-linked acetylcholine receptor from Caenorhabditis elegans.

Q6B959	APLD1_RAT	Apolipoprotein L domain-containing protein 1	15102925	Verge: a novel vascular early response gene.

Q02252	MMSA_HUMAN	Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial	1527093	CoA-dependent methylmalonate-semialdehyde dehydrogenase, a unique member of the aldehyde dehydrogenase superfamily. cDNA cloning, evolutionary relationships, and tissue distribution.

Q12060	HFI1_YEAST	Transcriptional coactivator HFI1/ADA1	12446794	The novel SLIK histone acetyltransferase complex functions in the yeast retrograde response pathway.

P61517	CAN_ECOLI	Carbonic anhydrase 2	11316870	Crystal structure of E. coli beta-carbonic anhydrase, an enzyme with an unusual pH-dependent activity.

Q9UQ84	EXO1_HUMAN	Exonuclease 1	11429708	HNPCC mutations in the human DNA mismatch repair gene hMLH1 influence assembly of hMutLalpha and hMLH1-hEXO1 complexes.

P18135	KV312_HUMAN	Ig kappa chain V-III region HAH	3127527	Autoantibody-associated kappa light chain variable region gene expressed in chronic lymphocytic leukemia with little or no somatic mutation. Implications for etiology and immunotherapy.

Q14914	PTGR1_HUMAN	Prostaglandin reductase 1	8576264	cDNA cloning, expression, and mutagenesis study of leukotriene B4 12- hydroxydehydrogenase.

Q9PW35	VMACA_AGKAC	Zinc metalloproteinase acutolysin-A	10482389	Molecular cloning and sequence analysis of cDNA encoding haemorrhagic toxin acutolysin A from Agkistrodon acutus.

Q9T0K5	LRX3_ARATH	Leucine-rich repeat extensin-like protein 3	11701884	Role of SH3 domain-containing proteins in clathrin-mediated vesicle trafficking in Arabidopsis.

Q9UST7	SFC3_SCHPO	Transcription factor tau subunit sfc3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8WXG9	GPR98_HUMAN	G-protein coupled receptor 98	11606593	Very large G protein-coupled receptor-1, the largest known cell surface protein, is highly expressed in the developing central nervous system.

Q15612	OR1Q1_HUMAN	Olfactory receptor 1Q1	9119360	Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species.

P40793	CDC42_DROME	Cdc42 homolog	12490550	Mbt, a Drosophila PAK protein, combines with Cdc42 to regulate photoreceptor cell morphogenesis.

Q08499	PDE4D_HUMAN	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	9371713	Characterization of five different proteins produced by alternatively spliced mRNAs from the human cAMP-specific phosphodiesterase PDE4D gene.

Q24155	TRUNK_DROME	Protein trunk	7590233	Similarities between trunk and spatzle, putative extracellular ligands specifying body pattern in Drosophila.

Q9FQ02	XRN2_ARATH	5'-3' exoribonuclease 2	17993620	Arabidopsis FIERY1, XRN2, and XRN3 are endogenous RNA silencing suppressors.

P54904	P5CR1_ARATH	Pyrroline-5-carboxylate reductase	8022935	Osmoregulation of a pyrroline-5-carboxylate reductase gene in Arabidopsis thaliana.

P98174	FGD1_HUMAN	FYVE, RhoGEF and PH domain-containing protein 1	8969170	The faciogenital dysplasia gene product FGD1 functions as a Cdc42Hs- specific guanine-nucleotide exchange factor.

O60503	ADCY9_HUMAN	Adenylate cyclase type 9	9628827	Cloning, chromosomal mapping, and regulatory properties of the human type 9 adenylyl cyclase (ADCY9).

Q96MM3	ZFP42_HUMAN	Zinc finger protein 42 homolog	16344273	Decreased expression of the human stem cell marker, Rex-1 (zfp-42), in renal cell carcinoma.

P80365	DHI2_HUMAN	Corticosteroid 11-beta-dehydrogenase isozyme 2	7859916	Cloning and tissue distribution of the human 11 beta-hydroxysteroid dehydrogenase type 2 enzyme.

P01721	LV601_HUMAN	Ig lambda chain V-VI region AR	6797401	The complete amino acid sequence of a prototype immunoglobulin-lambda light-chain-type amyloid-fibril protein AR.

Q63661	MUC4_RAT	Mucin-4	9857062	Post-transcriptional regulation of a milk membrane protein, the sialomucin complex (Ascites sialoglycoprotein (ASGP)-1/ASGP-2, rat muc4), by transforming growth factor beta.

P20339	RAB5A_HUMAN	Ras-related protein Rab-5A	2501306	The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion.

Q9UL62	TRPC5_HUMAN	Short transient receptor potential channel 5	10493832	Molecular cloning and characterization of TRPC5 (HTRP5), the human homologue of a mouse brain receptor-activated capacitative Ca(2+) entry channel.

Q9Y6E7	SIRT4_HUMAN	NAD-dependent ADP-ribosyltransferase sirtuin-4	16079181	Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins.

P0A7J7	RL11_ECOLI	50S ribosomal protein L11	7004866	Purification and primary structure determination of the N-terminal blocked protein, L11, from Escherichia coli ribosomes.

Q12326	PMG3_YEAST	Phosphoglycerate mutase 3	9544241	Investigation of two yeast genes encoding putative isoenzymes of phosphoglycerate mutase.

Q92462	PUB1_SCHPO	E3 ubiquitin-protein ligase pub1	8635463	Pub1 acts as an E6-AP-like protein ubiquitiin ligase in the degradation of cdc25.

Q86YW5	TRML1_HUMAN	Trem-like transcript 1 protein	12645956	The human TREM gene cluster at 6p21.1 encodes both activating and inhibitory single IgV domain receptors and includes NKp44.

Q943E7	HS16C_ORYSJ	16.9 kDa class I heat shock protein 3	15803416	Characterization of the genomic structures and selective expression profiles of nine class I small heat shock protein genes clustered on two chromosomes in rice (Oryza sativa L.).

P17511	MT1_CAEEL	Metallothionein-1	8428932	The novel metallothionein genes of Caenorhabditis elegans. Structural organization and inducible, cell-specific expression.

P97718	ADA1A_MOUSE	Alpha-1A adrenergic receptor	9630362	Molecular cloning, expression and characterization of cDNA encoding a mouse alpha1a-adrenoceptor.

P19313	CYTS_RAT	Cystatin-S	1537554	Structure, organization and regulation of a rat cysteine proteinase inhibitor-encoding gene.

Q7Z417	NUFP2_HUMAN	Nuclear fragile X mental retardation-interacting protein 2	12837692	82-FIP, a novel FMRP (fragile X mental retardation protein) interacting protein, shows a cell cycle-dependent intracellular localization.

Q9PT68	FXD5B_XENLA	Forkhead box protein D5-B	15656969	Of fox and frogs: fox (fork head/winged helix) transcription factors in Xenopus development.

P49848	TAF6_HUMAN	Transcription initiation factor TFIID subunit 6	8262073	Cloning and expression of Drosophila TAFII60 and human TAFII70 reveal conserved interactions with other subunits of TFIID.

Q8IXJ9	ASXL1_HUMAN	Putative Polycomb group protein ASXL1	20436459	Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB.

Q62904	DHB7_RAT	3-keto-steroid reductase	8663045	Cloning and characterization of an ovarian-specific protein that associates with the short form of the prolactin receptor.

Q12191	BUG1_YEAST	Binder of USO1 and GRH1 protein 1	16269340	Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile.

Q00357	TOXA_COCCA	Putative HC-toxin efflux carrier TOXA	8704997	A putative cyclic peptide efflux pump encoded by the TOXA gene of the plant-pathogenic fungus Cochliobolus carbonum.

P53063	DOM3Z_YEAST	RAT1-interacting protein	15565157	The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II.

P33897	ABCD1_HUMAN	ATP-binding cassette sub-family D member 1	8441467	Putative X-linked adrenoleukodystrophy gene shares unexpected homology with ABC transporters.

P34223	UBX1_YEAST	UBX domain-containing protein 1	15258615	Shp1 and Ubx2 are adaptors of Cdc48 involved in ubiquitin-dependent protein degradation.

Q06587	RING1_HUMAN	E3 ubiquitin-protein ligase RING1	16943429	Polycomb group and SCF ubiquitin ligases are found in a novel BCOR complex that is recruited to BCL6 targets.

P46946	COM1_YEAST	DNA endonuclease SAE2	9215888	A general method for identifying recessive diploid-specific mutations in Saccharomyces cerevisiae, its application to the isolation of mutants blocked at intermediate stages of meiotic prophase and characterization of a new gene SAE2.

P38148	PPS1_YEAST	Dual specificity protein phosphatase PPS1	9083070	The PPS1 gene of Saccharomyces cerevisiae codes for a dual specificity protein phosphatase with a role in the DNA synthesis phase of the cell cycle.

Q9V3Q6	M3K7_DROME	Mitogen-activated protein kinase kinase kinase 7	10757786	TAK1 participates in c-Jun N-terminal kinase signaling during Drosophila development.

O14793	GDF8_HUMAN	Growth/differentiation factor 8	9843994	Organization of the human myostatin gene and expression in healthy men and HIV-infected men with muscle wasting.

P25574	EMC1_YEAST	ER membrane protein complex subunit 1	14562095	Global analysis of protein localization in budding yeast.

O88543	CSN3_MOUSE	COP9 signalosome complex subunit 3	9707402	The COP9 complex is conserved between plants and mammals and is related to the 26S proteasome regulatory complex.

O00453	LST1_HUMAN	Leukocyte-specific transcript 1 protein	10706707	LST1: a gene with extensive alternative splicing and immunomodulatory function.

Q7L9L4	MOL1A_HUMAN	Mps one binder kinase activator-like 1A	19739119	Molecular characterization of human homologs of yeast MOB1.

Q9DC28	KC1D_MOUSE	Casein kinase I isoform delta	19414593	Casein kinase 1 delta regulates the pace of the mammalian circadian clock.

P40459	PANC_YEAST	Pantoate--beta-alanine ligase	11154694	Saccharomyces cerevisiae is capable of de novo pantothenic acid biosynthesis involving a novel pathway of beta-alanine production from spermine.

P32303	AGTRA_XENLA	Type-1 angiotensin II receptor A	7688227	Molecular cloning, sequencing and functional expression of an amphibian angiotensin II receptor.

O13952	CNL2_SCHPO	Centromere-localized protein 2	17035632	Reconstruction of the kinetochore during meiosis in fission yeast Schizosaccharomyces pombe.

Q9WTW7	S23A1_RAT	Solute carrier family 23 member 1	10331392	A family of mammalian Na+-dependent L-ascorbic acid transporters.

Q9NVM9	M89BB_HUMAN	Cell cycle regulator Mat89Bb homolog	15737938	Drosophila genome-scale screen for PAN GU kinase substrates identifies Mat89Bb as a cell cycle regulator.

Q93ZM7	CH60C_ARATH	Chaperonin CPN60-like 2, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P35408	PE2R4_HUMAN	Prostaglandin E2 receptor EP4 subtype	8163486	Cloning, functional expression, and characterization of the human prostaglandin E2 receptor EP2 subtype.

Q76DI2	BGBP_TENMO	Beta-1,3-glucan-binding protein	12923175	Characterization and properties of a 1,3-beta-D-glucan pattern recognition protein of Tenebrio molitor larvae that is specifically degraded by serine protease during prophenoloxidase activation.

O42997	YBC7_SCHPO	Uncharacterized protein C27B12.07	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P48582	BRO1_YEAST	Vacuolar-sorting protein BRO1	12668726	Bro1 is an endosome-associated protein that functions in the MVB pathway in Saccharomyces cerevisiae.

Q10P60	HS26P_ORYSJ	26.7 kDa heat shock protein, chloroplastic	19135278	Expression analysis of nine rice heat shock protein genes under abiotic stresses and ABA treatment.

Q80WV3	CHST2_MOUSE	Carbohydrate sulfotransferase 2	9712885	Molecular cloning and characterization of an N-acetylglucosamine-6-O- sulfotransferase.

Q2WF59	ZER1_CAEEL	Zyg eleven-related protein 1	17304241	The Caenorhabditis elegans cell-cycle regulator ZYG-11 defines a conserved family of CUL-2 complex components.

Q04637	IF4G1_HUMAN	Eukaryotic translation initiation factor 4 gamma 1	16513844	Post-transcriptional regulation of thioredoxin by the stress inducible heterogenous ribonucleoprotein A18.

P50080	AZR1_YEAST	Azole resistance protein 1	11113970	Expression of the AZR1 gene (ORF YGR224w), encoding a plasma membrane transporter of the major facilitator superfamily, is required for adaptation to acetic acid and resistance to azoles in Saccharomyces cerevisiae.

P53809	PPCT_RAT	Phosphatidylcholine transfer protein	10415339	Cloning and gene structure of rat phosphatidylcholine transfer protein, Pctp.

O75074	LRP3_HUMAN	Low-density lipoprotein receptor-related protein 3	9693042	cDNA cloning of a new low-density lipoprotein receptor-related protein and mapping of its gene (LRP3) to chromosome bands 19q12-q13. 2.

O95279	KCNK5_HUMAN	Potassium channel subfamily K member 5	9812978	Cloning and expression of a novel pH-sensitive two pore domain K+ channel from human kidney.

Q9M0K4	LAF1_ARATH	Transcription factor LAF1	12827204	LAF1 ubiquitination by COP1 controls photomorphogenesis and is stimulated by SPA1.

Q01484	ANK2_HUMAN	Ankyrin-2	15611082	The ammonium transporter RhBG: requirement of a tyrosine-based signal and ankyrin-G for basolateral targeting and membrane anchorage in polarized kidney epithelial cells.

P17096	HMGA1_HUMAN	High mobility group protein HMG-I/HMG-Y	2505228	Cloning of cDNAs coding for human HMG I and HMG Y proteins: both are capable of binding to the octamer sequence motif.

Q9US03	KLP2_SCHPO	Kinesin-like protein 2	11694582	pkl1(+)and klp2(+): two kinesins of the Kar3 subfamily in fission yeast perform different functions in both mitosis and meiosis.

O75832	PSD10_HUMAN	26S proteasome non-ATPase regulatory subunit 10	18040287	Oncoprotein p28 GANK binds to RelA and retains NF-kappaB in the cytoplasm through nuclear export.

P85024	BKIP_CROVV	Bradykinin inhibitor peptide	16277978	Identification and functional analysis of a novel bradykinin inhibitory peptide in the venoms of new world crotalinae pit vipers.

O74485	CUE3_SCHPO	CUE domain-containing protein 3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q92847	GHSR_HUMAN	Growth hormone secretagogue receptor type 1	8688086	A receptor in pituitary and hypothalamus that functions in growth hormone release.

P63072	UBD_MOUSE	Ubiquitin D	19959714	The ubiquitin-like protein FAT10 mediates NF-kappa-B activation.

Q7K550	EIF3J_DROME	Eukaryotic translation initiation factor 3 subunit J	17392269	The essential Drosophila ATP-binding cassette domain protein, pixie, binds the 40 S ribosome in an ATP-dependent manner and is required for translation initiation.

Q61221	HIF1A_MOUSE	Hypoxia-inducible factor 1-alpha	15225651	Increase of SUMO-1 expression in response to hypoxia: direct interaction with HIF-1alpha in adult mouse brain and heart in vivo.

O75002	MOG1_SCHPO	Nuclear import protein mog1	11290708	Fission yeast Mog1p homologue, which interacts with the small GTPase Ran, is required for mitosis-to-interphase transition and poly(A)(+) RNA metabolism.

Q495M3	S36A2_HUMAN	Proton-coupled amino acid transporter 2	12809675	A cluster of proton/amino acid transporter genes in the human and mouse genomes.

Q9FH02	FTSH5_ARATH	ATP-dependent zinc metalloprotease FTSH 5, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q9UUH0	YKIC_SCHPO	Uncharacterized protein C630.12	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q42472	DCE2_ARATH	Glutamate decarboxylase 2	9700069	Two isoforms of glutamate decarboxylase in Arabidopsis are regulated by calcium/calmodulin and differ in organ distribution.

P13864	DNMT1_MOUSE	DNA (cytosine-5)-methyltransferase 1	16085498	The PHD finger/bromodomain of NoRC interacts with acetylated histone H4K16 and is sufficient for rDNA silencing.

P52923	AIF1_YEAST	Apoptosis-inducing factor 1	15381687	An AIF orthologue regulates apoptosis in yeast.

Q06001	FAR10_YEAST	Factor arrest protein 10	12588993	Far3 and five interacting proteins prevent premature recovery from pheromone arrest in the budding yeast Saccharomyces cerevisiae.

Q9S841	PSBO2_ARATH	Oxygen-evolving enhancer protein 1-2, chloroplastic	15722336	The manganese-stabilizing protein is required for photosystem II assembly/stability and photoautotrophy in higher plants.

P50878	RL4_RAT	60S ribosomal protein L4	15684048	Cold stress-induced protein Rbm3 binds 60S ribosomal subunits, alters microRNA levels, and enhances global protein synthesis.

P16284	PECA1_HUMAN	Platelet endothelial cell adhesion molecule	18672896	Regulation of G protein-coupled receptor activities by the platelet- endothelial cell adhesion molecule, PECAM-1.

P97524	S27A2_RAT	Very long-chain acyl-CoA synthetase	8939997	Molecular cloning of cDNA encoding rat very long-chain acyl-CoA synthetase.

P53849	GIS2_YEAST	Zinc finger protein GIS2	10628841	Yeast genes GIS1-4: multicopy suppressors of the Gal- phenotype of snf1 mig1 srb8/10/11 cells.

P31327	CPSM_HUMAN	Carbamoyl-phosphate synthase [ammonia], mitochondrial	1840546	Cloning and sequence of a cDNA encoding human carbamyl phosphate synthetase I: molecular analysis of hyperammonemia.

Q4FE45	XB33_ARATH	E3 ubiquitin-protein ligase XBAT33	15644464	Functional analysis of the RING-type ubiquitin ligase family of Arabidopsis.

Q559R0	SAR1A_DICDI	GTP-binding protein Sar1A	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

P25105	PTAFR_HUMAN	Platelet-activating factor receptor	1656963	Characterization of a human cDNA that encodes a functional receptor for platelet activating factor.

P34630	CUTC_CAEEL	Copper homeostasis protein cutC homolog	18723824	Knock down of Caenorhabditis elegans cutc-1 exacerbates the sensitivity toward high levels of copper.

P50914	RL14_HUMAN	60S ribosomal protein L14	9480843	Triplet repeat-containing ribosomal protein L14 gene in immortalized human endothelial cell line (t-HUE4).

Q9M065	PP352_ARATH	Pentatricopeptide repeat-containing protein At4g36680, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q14940	SL9A5_HUMAN	Sodium/hydrogen exchanger 5	9933641	Molecular cloning, genomic organization, and functional expression of Na+/H+ exchanger isoform 5 (NHE5) from human brain.

Q9JLB9	PVRL3_MOUSE	Poliovirus receptor-related protein 3	15728677	Roles of cell-adhesion molecules nectin 1 and nectin 3 in ciliary body development.

O22152	YAB1_ARATH	Axial regulator YABBY 1	9878633	FILAMENTOUS FLOWER controls the formation and development of Arabidopsis inflorescences and floral meristems.

Q9QUH3	APOA5_RAT	Apolipoprotein A-V	11577099	Apolipoprotein A-V. A novel apolipoprotein associated with an early phase of liver regeneration.

Q9Y5Y4	GPR44_HUMAN	Putative G-protein coupled receptor 44	9973380	Selective expression of a novel surface molecule by human Th2 cells in vivo.

Q9Y5X5	NPFF2_HUMAN	Neuropeptide FF receptor 2	10851242	Receptor for the pain modulatory neuropeptides FF and AF is an orphan G protein-coupled receptor.

Q8NF91	SYNE1_HUMAN	Nesprin-1	12408964	The nesprins are giant actin-binding proteins, orthologous to Drosophila melanogaster muscle protein MSP-300.

Q8WYQ5	DGCR8_HUMAN	Microprocessor complex subunit DGCR8	17704815	Crystal structure of human DGCR8 core.

O49561	G2OX8_ARATH	Gibberellin 2-beta-dioxygenase 8	12509528	Overexpression of a novel class of gibberellin 2-oxidases decreases gibberellin levels and creates dwarf plants.

Q61091	FZD8_MOUSE	Frizzled-8	11520064	Identification of a PDZ domain containing Golgi protein, GOPC, as an interaction partner of frizzled.

P53438	SOK2_YEAST	Protein SOK2	8524252	SOK2 may regulate cyclic AMP-dependent protein kinase-stimulated growth and pseudohyphal development by repressing transcription.

Q9FGF8	ABR1_ARATH	Ethylene-responsive transcription factor ABR1	16227468	ABR1, an APETALA2-domain transcription factor that functions as a repressor of ABA response in Arabidopsis.

P53010	PAN2_YEAST	PAB-dependent poly(A)-specific ribonuclease subunit PAN2	14562095	Global analysis of protein localization in budding yeast.

O95229	ZWINT_HUMAN	ZW10 interactor	16732327	Hec1 sequentially recruits Zwint-1 and ZW10 to kinetochores for faithful chromosome segregation and spindle checkpoint control.

Q9CPY1	RM51_MOUSE	39S ribosomal protein L51, mitochondrial	11402041	Proteomic analysis of the mammalian mitochondrial ribosome. Identification of protein components in the 28S small subunit.

P38146	YPT10_YEAST	GTP-binding protein YPT10	14562095	Global analysis of protein localization in budding yeast.

Q10277	MSA1_SCHPO	Multicopy suppressor of sporulation protein msa1	15166138	A novel gene, msa1, inhibits sexual differentiation in Schizosaccharomyces pombe.

Q03373	DIG2_YEAST	Down-regulator of invasive growth 2	9094309	Regulation of the mating pheromone and invasive growth responses in yeast by two MAP kinase substrates.

Q14527	HLTF_HUMAN	Helicase-like transcription factor	7876228	Cloning of an SNF2/SWI2-related protein that binds specifically to the SPH motifs of the SV40 enhancer and to the HIV-1 promoter.

O15350	P73_HUMAN	Tumor protein p73	10391251	p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage.

Q9UU76	PUF6_SCHPO	Pumilio homology domain family member 6	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q67X83	HS26M_ORYSJ	26.2 kDa heat shock protein, mitochondrial	19703271	Rice sHsp genes: genomic organization and expression profiling under stress and development.

P20382	MCH_HUMAN	Pro-MCH	8326825	Isolation and characterization of the human melanin-concentrating hormone gene and a variant gene.

Q2L6W9	SAX1_CAEEL	Serine/threonine-protein kinase sax-1	10982409	Neuronal cell shape and neurite initiation are regulated by the Ndr kinase SAX-1, a member of the Orb6/COT-1/warts serine/threonine kinase family.

O75496	GEMI_HUMAN	Geminin	9635433	Geminin, an inhibitor of DNA replication, is degraded during mitosis.

Q9HGP5	CAPZB_SCHPO	F-actin-capping protein subunit beta	15743909	Profilin-mediated competition between capping protein and formin Cdc12p during cytokinesis in fission yeast.

P32255	TBA_DICDI	Tubulin alpha chain	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

Q9KIZ4	C167_SORCE	Cytochrome P450 167A1	10831849	Isolation and characterization of the epothilone biosynthetic gene cluster from Sorangium cellulosum.

Q06213	MED10_YEAST	Mediator of RNA polymerase II transcription subunit 10	9812975	Identification of new mediator subunits in the RNA polymerase II holoenzyme from Saccharomyces cerevisiae.

Q9US25	HRP1_SCHPO	Chromodomain helicase hrp1	9520266	Isolation and characterization of hrp1+, a new member of the SNF2/SWI2 gene family from the fission yeast Schizosaccharomyces pombe.

P05093	CP17A_HUMAN	Steroid 17-alpha-hydroxylase/17,20 lyase	3500022	Cloning and sequence of the human gene for P450c17 (steroid 17 alpha- hydroxylase/17,20 lyase): similarity with the gene for P450c21.

P50607	TUB_HUMAN	Tubby protein homolog	19837063	Identification of tubby and tubby-like protein 1 as eat-me signals by phage display.

P32623	CRH2_YEAST	Probable glycosidase CRH2	15781460	Comprehensive proteomic analysis of Saccharomyces cerevisiae cell walls: identification of proteins covalently attached via glycosylphosphatidylinositol remnants or mild alkali-sensitive linkages.

P53010	PAN2_YEAST	PAB-dependent poly(A)-specific ribonuclease subunit PAN2	11953437	Posttranscriptional regulation of the RAD5 DNA repair gene by the Dun1 kinase and the Pan2-Pan3 poly(A)-nuclease complex contributes to survival of replication blocks.

Q62351	TFR1_MOUSE	Transferrin receptor protein 1	10192390	Transferrin receptor is necessary for development of erythrocytes and the nervous system.

P51675	CCR1_MOUSE	C-C chemokine receptor type 1	7594543	Molecular characterization of two murine eosinophil beta chemokine receptors.

P49286	MTR1B_HUMAN	Melatonin receptor type 1B	7568007	Molecular characterization of a second melatonin receptor expressed in human retina and brain: the Mel1b melatonin receptor.

P16284	PECA1_HUMAN	Platelet endothelial cell adhesion molecule	12110892	Apoptosis disables CD31-mediated cell detachment from phagocytes promoting binding and engulfment.

Q9W0V1	PDPK1_DROME	3-phosphoinositide-dependent protein kinase 1	11344272	Drosophila phosphoinositide-dependent kinase-1 regulates apoptosis and growth via the phosphoinositide 3-kinase-dependent signaling pathway.

Q06107	YP114_YEAST	Uncharacterized TLC domain-containing protein YPR114W	14562095	Global analysis of protein localization in budding yeast.

O61213	DUOX1_CAEEL	Dual oxidase 1	11514595	Tyrosine cross-linking of extracellular matrix is catalyzed by Duox, a multidomain oxidase/peroxidase with homology to the phagocyte oxidase subunit gp91phox.

Q9XZT1	MED18_DROME	Mediator of RNA polymerase II transcription subunit 18	12021283	Novel Mediator proteins of the small Mediator complex in Drosophila SL2 cells.

Q9LDU6	ST7R_ARATH	7-dehydrocholesterol reductase	10758495	Lesions in the sterol delta reductase gene of Arabidopsis cause dwarfism due to a block in brassinosteroid biosynthesis.

P75831	MACB_ECOLI	Macrolide export ATP-binding/permease protein macB	11544226	Novel macrolide-specific ABC-type efflux transporter in Escherichia coli.

Q9WVC2	LYNX1_MOUSE	Ly-6/neurotoxin-like protein 1	11906696	Novel modulation of neuronal nicotinic acetylcholine receptors by association with the endogenous prototoxin lynx1.

Q09696	MED1_SCHPO	Mediator of RNA polymerase II transcription subunit 1	10625684	Purification and characterization of RNA polymerase II holoenzyme from Schizosaccharomyces pombe.

P13432	SMR1_RAT	SMR1 protein	12835417	Sialorphin, a natural inhibitor of rat membrane-bound neutral endopeptidase that displays analgesic activity.

Q84JM4	TPR3_ARATH	Topless-related protein 3	16763149	TOPLESS regulates apical embryonic fate in Arabidopsis.

O02193	MOF_DROME	Males-absent on the first protein	9155031	mof, a putative acetyl transferase gene related to the Tip60 and MOZ human genes and to the SAS genes of yeast, is required for dosage compensation in Drosophila.

P40086	COX15_YEAST	Cytochrome c oxidase assembly protein COX15	11248251	Involvement of mitochondrial ferredoxin and Cox15p in hydroxylation of heme O.

Q9W6A7	OPSR1_DANRE	Red-sensitive opsin-1	10349978	ERRATUM
O43920	NDUS5_HUMAN	NADH dehydrogenase [ubiquinone] iron-sulfur protein 5	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

Q9VLA2	GCM2_DROME	Transcription factor glial cells missing 2	11532931	Glide2, a second glial promoting factor in Drosophila melanogaster.

Q15628	TRADD_HUMAN	Tumor necrosis factor receptor type 1-associated DEATH domain protein	8612133	TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex.

P50281	MMP14_HUMAN	Matrix metalloproteinase-14	9724659	Crystal structure of the complex formed by the membrane type 1-matrix metalloproteinase with the tissue inhibitor of metalloproteinases-2, the soluble progelatinase A receptor.

O75636	FCN3_HUMAN	Ficolin-3	9694814	Cloning and characterization of the Hakata antigen, a member of the ficolin/opsonin p35 lectin family.

P38874	ELP5_YEAST	Elongator complex protein 5	15769872	An early step in wobble uridine tRNA modification requires the Elongator complex.

Q6DC66	BOKA_DANRE	Bcl-2-related ovarian killer protein homolog A	16888646	Functional characterization of the Bcl-2 gene family in the zebrafish.

P62081	RS7_HUMAN	40S ribosomal protein S7	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

Q13394	MB211_HUMAN	Protein mab-21-like 1	8733127	cDNA cloning of a human homologue of the Caenorhabditis elegans cell fate-determining gene mab-21: expression, chromosomal localization and analysis of a highly polymorphic (CAG)n trinucleotide repeat.

O82261	DEGP2_ARATH	Protease Do-like 2, chloroplastic	11179216	A chloroplast DegP2 protease performs the primary cleavage of the photodamaged D1 protein in plant photosystem II.

Q86IC8	CAMT2_DICDI	Probable caffeoyl-CoA O-methyltransferase 2	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q9NZD1	GPC5D_HUMAN	G-protein coupled receptor family C group 5 member D	11311935	Cloning and characterization of a human orphan family C G-protein coupled receptor GPRC5D.

P39720	OAF1_YEAST	Oleate-activated transcription factor 1	8972187	A complex containing two transcription factors regulates peroxisome proliferation and the coordinate induction of beta-oxidation enzymes in Saccharomyces cerevisiae.

Q5XEP9	KCS17_ARATH	3-ketoacyl-CoA synthase 17	15277688	Specific and differential inhibition of very-long-chain fatty acid elongases from Arabidopsis thaliana by different herbicides.

Q9Z0X0	BORG3_MOUSE	Cdc42 effector protein 5	10490598	The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins.

P00899	TRPE_YEAST	Anthranilate synthase component 1	8432699	Analysis of feedback-resistant anthranilate synthases from Saccharomyces cerevisiae.

Q99P58	RB27B_MOUSE	Ras-related protein Rab-27B	18940604	Structural basis for the exclusive specificity of Slac2- a/melanophilin for the Rab27 GTPases.

Q12333	FRE7_YEAST	Ferric/cupric reductase transmembrane component 7	17553781	Identification of a vacuole-associated metalloreductase and its role in Ctr2-mediated intracellular copper mobilization.

P13796	PLSL_HUMAN	Plastin-2	2252891	65-kilodalton protein phosphorylated by interleukin 2 stimulation bears two putative actin-binding sites and two calcium-binding sites.

P35999	PMIP_YEAST	Mitochondrial intermediate peptidase	8831696	Mutations in a putative zinc-binding domain inactivate the mitochondrial intermediate peptidase.

Q96HW7	INT4_HUMAN	Integrator complex subunit 4	16239144	Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.

P0A8U0	SYDP_ECOLI	Protein syd	7890670	Product of a new gene, syd, functionally interacts with SecY when overproduced in Escherichia coli.

Q9H0V9	LMA2L_HUMAN	VIP36-like protein	12609988	Profile-based data base scanning for animal L-type lectins and characterization of VIPL, a novel VIP36-like endoplasmic reticulum protein.

Q96RQ3	MCCA_HUMAN	Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial	11170888	The molecular basis of 3-methylcrotonylglycinuria, a disorder of leucine catabolism.

Q14790	CASP8_HUMAN	Caspase-8	8681376	Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death.

Q96D31	CRCM1_HUMAN	Calcium release-activated calcium channel protein 1	16733527	Amplification of CRAC current by STIM1 and CRACM1 (Orai1).

Q9Y6Q9	NCOA3_HUMAN	Nuclear receptor coactivator 3	15698540	FLASH interacts with p160 coactivator subtypes and differentially suppresses transcriptional activity of steroid hormone receptors.

O42844	KCC2_SCHPO	Calcium/calmodulin-dependent protein kinase type II	12589433	Mkp1 and Mkp2, two MAPKAP-kinase homologues in Schizosaccharomyces pombe, interact with the MAP kinase Sty1.

Q92858	ATOH1_HUMAN	Protein atonal homolog 1	8872459	Evolutionary conservation of sequence and expression of the bHLH protein Atonal suggests a conserved role in neurogenesis.

Q9Y885	TOXF_COCCA	Putative branched-chain-amino-acid aminotransferase TOXF	10627051	A putative branched-chain-amino-acid transaminase gene required for HC-toxin biosynthesis and pathogenicity in Cochliobolus carbonum.

P53877	IPI3_YEAST	Pre-rRNA-processing protein IPI3	14690591	Assigning function to yeast proteins by integration of technologies.

P46959	TRM61_YEAST	tRNA (adenine-N(1)-)-methyltransferase catalytic subunit TRM61	9851972	The essential Gcd10p-Gcd14p nuclear complex is required for 1- methyladenosine modification and maturation of initiator methionyl- tRNA.

O94317	YH5D_SCHPO	Uncharacterized serine-rich protein C215.13	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8K4D7	PLCZ1_MOUSE	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1	12117804	PLC zeta: a sperm-specific trigger of Ca(2+) oscillations in eggs and embryo development.

P19018	TRA2_DROME	Transformer-2 sex-determining protein	8124712	The role of specific protein-RNA and protein-protein interactions in positive and negative control of pre-mRNA splicing by Transformer 2.

Q9UN70	PCDGK_HUMAN	Protocadherin gamma-C3	8508762	Protocadherins: a large family of cadherin-related molecules in central nervous system.

P01613	KV121_HUMAN	Ig kappa chain V-I region Ni	4709625	Amino acid sequence of a human kappa type Bence-Jones protein. II. Chymotryptic peptides and sequence of protein Ni.

Q8T9R8	STMX_STOCA	Stomoxyn	12372834	Epithelial innate immunity. A novel antimicrobial peptide with antiparasitic activity in the blood-sucking insect Stomoxys calcitrans.

Q9UHP3	UBP25_HUMAN	Ubiquitin carboxyl-terminal hydrolase 25	10644437	USP25, a novel gene encoding a deubiquitinating enzyme, is located in the gene-poor region 21q11.2.

Q9Z1P2	ACTN1_RAT	Alpha-actinin-1	15505042	Pdlim2, a novel PDZ-LIM domain protein, interacts with alpha-actinins and filamin A.

Q9M2Y9	RAX3_ARATH	Transcription factor RAX3	16463103	The MYB transcription factor superfamily of Arabidopsis: expression analysis and phylogenetic comparison with the rice MYB family.

Q86TX2	ACOT1_HUMAN	Acyl-coenzyme A thioesterase 1	16940157	Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs.

P55822	SH3BG_HUMAN	SH3 domain-binding glutamic acid-rich protein	9050928	Cloning a new human gene from chromosome 21q22.3 encoding a glutamic acid-rich protein expressed in heart and skeletal muscle.

Q01134	CHKA_RAT	Choline kinase alpha	7852267	Regulation of choline kinase R: analyses of alternatively spliced choline kinases and the promoter region.

P16109	LYAM3_HUMAN	P-selectin	11237770	A new member of the sorting nexin family interacts with the C- terminus of P-selectin.

P37595	IAAA_ECOLI	Isoaspartyl peptidase	15946951	Crystal structure of isoaspartyl aminopeptidase in complex with L- aspartate.

P53199	ERG26_YEAST	Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating	9811880	Characterization of the Saccharomyces cerevisiae ERG26 gene encoding the C-3 sterol dehydrogenase (C-4 decarboxylase) involved in sterol biosynthesis.

Q7TNN9	RHCG_RAT	Ammonium transporter Rh type C	12138130	Expression of RhCG, a new putative NH(3)/NH(4)(+) transporter, along the rat nephron.

Q24008	INAD_DROME	Inactivation-no-after-potential D protein	7826638	A novel protein encoded by the InaD gene regulates recovery of visual transduction in Drosophila.

Q9UT59	YKJ7_SCHPO	Putative uncharacterized oxidoreductase C513.07	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9ZVR7	PSKR1_ARATH	Phytosulfokine receptor 1	16829587	Disruption and overexpression of Arabidopsis phytosulfokine receptor gene affects cellular longevity and potential for growth.

O14021	PRW1_SCHPO	RbAp48-related WD40 repeat-containing protein prw1	12773392	Alp13, an MRG family protein, is a component of fission yeast Clr6 histone deacetylase required for genomic integrity.

Q9DBP0	NPT2B_MOUSE	Sodium-dependent phosphate transport protein 2B	9826740	Characterization of a murine type II sodium-phosphate cotransporter expressed in mammalian small intestine.

P84805	CRV25_NAJKA	Cysteine-rich venom protein 25	15670767	Cobra venom contains a pool of cysteine-rich secretory proteins.

P29774	ETS3_DROME	DNA-binding protein D-ETS-3	1577186	Isolation and characterization of five Drosophila genes that encode an ets-related DNA binding domain.

P49427	UB2R1_HUMAN	Ubiquitin-conjugating enzyme E2 R1	19945379	Rapid E2-E3 assembly and disassembly enable processive ubiquitylation of cullin-RING ubiquitin ligase substrates.

P40555	PSMD9_YEAST	Probable 26S proteasome regulatory subunit p27	19446322	Multiple assembly chaperones govern biogenesis of the proteasome regulatory particle base.

Q8I7I5	ROL3_CAEEL	Protein roller-3	1752418	Genetic analysis of a major segment [LGV(left)] of the genome of Caenorhabditis elegans.

Q04118	PRB3_HUMAN	Basic salivary proline-rich protein 3	1894623	Structure and bacterial receptor activity of a human salivary proline-rich glycoprotein.

Q9ERC8	DSCAM_MOUSE	Down syndrome cell adhesion molecule homolog	19945391	DSCAM and DSCAML1 function in self-avoidance in multiple cell types in the developing mouse retina.

P25719	CYPC_YEAST	Peptidyl-prolyl cis-trans isomerase C, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q84JA6	CESA4_ARATH	Cellulose synthase A catalytic subunit 4 [UDP-forming]	17351116	Impairment of cellulose synthases required for Arabidopsis secondary cell wall formation enhances disease resistance.

Q8VSC3	IPA9_SHIFL	E3 ubiquitin-protein ligase ipaH9.8	20010814	A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKgamma to dampen the host NF-kappaB-mediated inflammatory response.

Q9BXJ9	NAA15_HUMAN	N-alpha-acetyltransferase 15, NatA auxiliary subunit	16507339	Cloning and characterization of hNAT5/hSAN: an evolutionarily conserved component of the NatA protein N-alpha-acetyltransferase complex.

Q99PJ1	PCD15_MOUSE	Protocadherin-15	11138007	The mouse Ames waltzer hearing-loss mutant is caused by mutation of Pcdh15, a novel protocadherin gene.

P53135	SLD3_YEAST	DNA replication regulator SLD3	11296242	Sld3, which interacts with Cdc45 (Sld4), functions for chromosomal DNA replication in Saccharomyces cerevisiae.

P40367	GPI7_YEAST	GPI ethanolamine phosphate transferase 2	15452134	GPI7 involved in glycosylphosphatidylinositol biosynthesis is essential for yeast cell separation.

O00587	MFNG_HUMAN	Beta-1,3-N-acetylglucosaminyltransferase manic fringe	9187150	A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway.

P39286	RSGA_ECOLI	Putative ribosome biogenesis GTPase RsgA	14973029	Studies of the interaction of Escherichia coli YjeQ with the ribosome in vitro.

P15018	LIF_HUMAN	Leukemia inhibitory factor	3143918	Leukaemia inhibitory factor is identical to the myeloid growth factor human interleukin for DA cells.

P15289	ARSA_HUMAN	Arylsulfatase A	12888274	Crystal structure of a covalent intermediate of endogenous human arylsulfatase A.

Q9R1T3	CATZ_RAT	Cathepsin Z	12553736	Determination of the mRNA sequence of cathepsin Y, a cysteine endopeptidase from rat spleen, and confirmation of its ubiquitous expression.

Q9LYA9	Y3314_ARATH	Uncharacterized protein At3g63140, chloroplastic	16461379	Protein profiling of plastoglobules in chloroplasts and chromoplasts. A surprising site for differential accumulation of metabolic enzymes.

Q9M9V8	CDPKA_ARATH	Calcium-dependent protein kinase 10	8943201	Ca2+-dependent protein kinases and stress signal transduction in plants.

Q12778	FOXO1_HUMAN	Forkhead box protein O1	12228231	Phosphorylation of serine 256 suppresses transactivation by FKHR (FOXO1) by multiple mechanisms. Direct and indirect effects on nuclear/cytoplasmic shuttling and DNA binding.

Q9H4D5	NXF3_HUMAN	Nuclear RNA export factor 3	11545741	Two closely related human nuclear export factors utilize entirely distinct export pathways.

P17540	KCRS_HUMAN	Creatine kinase S-type, mitochondrial	2324105	Separate nuclear genes encode sarcomere-specific and ubiquitous human mitochondrial creatine kinase isoenzymes.

Q9BV40	VAMP8_HUMAN	Vesicle-associated membrane protein 8	9614193	Endobrevin, a novel synaptobrevin/VAMP-like protein preferentially associated with the early endosome.

P05015	IFN16_HUMAN	Interferon alpha-16	6548765	Novel human leukocyte interferon subtype and structural comparison of alpha interferon genes.

Q9UL62	TRPC5_HUMAN	Short transient receptor potential channel 5	15757897	MxA, a member of the dynamin superfamily, interacts with the ankyrin- like repeat domain of TRPC.

Q9N2L7	PLK2_CAEEL	Serine/threonine-protein kinase plk-2	11092748	Caenorhabditis elegans contains a third polo-like kinase gene.

Q9FRL8	DHAR2_ARATH	Glutathione S-transferase DHAR2	12077129	Functional divergence in the glutathione transferase superfamily in plants. Identification of two classes with putative functions in redox homeostasis in Arabidopsis thaliana.

Q06287	EMG1_YEAST	Essential for mitotic growth 1	11694595	Novel stress-responsive genes EMG1 and NOP14 encode conserved, interacting proteins required for 40S ribosome biogenesis.

O59945	FIMB_SCHPO	Fimbrin	11694585	Interactions among a fimbrin, a capping protein, and an actin- depolymerizing factor in organization of the fission yeast actin cytoskeleton.

P10041	DL_DROME	Neurogenic locus protein delta	10935637	Glycosyltransferase activity of Fringe modulates Notch-Delta interactions.

P51610	HCFC1_HUMAN	Host cell factor 1	12244100	Host cell factor-1 interacts with and antagonizes transactivation by the cell cycle regulatory factor Miz-1.

P87176	SLX8_SCHPO	E3 ubiquitin-protein ligase complex slx8-rfp subunit slx8	17762864	Conserved function of RNF4 family proteins in eukaryotes: targeting a ubiquitin ligase to SUMOylated proteins.

P24928	RPB1_HUMAN	DNA-directed RNA polymerase II subunit RPB1	7622068	The human gene encoding the largest subunit of RNA polymerase II.

Q9H6Q3	SLAP2_HUMAN	Src-like-adapter 2	11891219	A novel Src homology 2 domain-containing molecule, Src-like adapter protein-2 (SLAP-2), which negatively regulates T cell receptor signaling.

O75715	GPX5_HUMAN	Epididymal secretory glutathione peroxidase	9639555	The majority of human glutathione peroxidase type 5 (GPX5) transcripts are incorrectly spliced: implications for the role of GPX5 in the male reproductive tract.

P61969	LMO4_MOUSE	LIM domain transcription factor LMO4	9860983	Mouse deformed epidermal autoregulatory factor 1 recruits a LIM domain factor, LMO-4, and CLIM coregulators.

O81796	IDH3_ARATH	Isocitrate dehydrogenase [NAD] regulatory subunit 3, mitochondrial	16527867	Expression analysis of Arabidopsis thaliana NAD-dependent isocitrate dehydrogenase genes shows the presence of a functional subunit that is mainly expressed in the pollen and absent from vegetative organs.

P46926	GNPI1_HUMAN	Glucosamine-6-phosphate isomerase 1	9438414	Molecularly cloned mammalian glucosamine-6-phosphate deaminase localizes to transporting epithelium and lacks oscillin activity.

Q39241	TRXH5_ARATH	Thioredoxin H5	14976236	The Arabidopsis cytosolic thioredoxin h5 gene induction by oxidative stress and its W-box-mediated response to pathogen elicitor.

Q9SCZ4	FERON_ARATH	Receptor-like protein kinase FERONIA	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

O95460	MATN4_HUMAN	Matrilin-4	15075323	Interactions between the cartilage oligomeric matrix protein and matrilins. Implications for matrix assembly and the pathogenesis of chondrodysplasias.

O96390	RACF1_DICDI	Rho-related protein racF1	15509655	Cellular distribution and functions of wild-type and constitutively activated Dictyostelium PakB.

P32522	PT309_YEAST	Pentatricopeptide repeat-containing protein PET309, mitochondrial	9692914	The Saccharomyces cerevisiae Pet309 protein is embedded in the mitochondrial inner membrane.

P83094	STIM_DROME	Stromal interaction molecule homolog	15866891	STIM1, an essential and conserved component of store-operated Ca2+ channel function.

Q9UM11	FZR_HUMAN	Fizzy-related protein homolog	9734353	Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1.

P41964	DMYC_DROME	Drosomycin	9736738	Differential display of peptides induced during the immune response of Drosophila: a matrix-assisted laser desorption ionization time-of- flight mass spectrometry study.

Q07008	NOTC1_RAT	Neurogenic locus notch homolog protein 1	1764995	A homolog of Drosophila Notch expressed during mammalian development.

Q6NXG1	ESRP1_HUMAN	Epithelial splicing regulatory protein 1	19285943	ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing.

P30711	GSTT1_HUMAN	Glutathione S-transferase theta-1	9434735	Kinetic characterization of recombinant human glutathione transferase T1-1, a polymorphic detoxication enzyme.

P22803	TRX2_YEAST	Thioredoxin-2	9657146	LMA1 binds to vacuoles at Sec18p (NSF), transfers upon ATP hydrolysis to a t-SNARE (Vam3p) complex, and is released during fusion.

P55215	CASP2_RAT	Caspase-2	12067235	Two caspase-2 transcripts are expressed in rat hippocampus after global cerebral ischemia.

Q13617	CUL2_HUMAN	Cullin-2	12609982	TIP120A associates with cullins and modulates ubiquitin ligase activity.

O15382	BCAT2_HUMAN	Branched-chain-amino-acid aminotransferase, mitochondrial	8702755	Two yeast homologs of ECA39, a target for c-Myc regulation, code for cytosolic and mitochondrial branched-chain amino acid aminotransferases.

Q13137	CACO2_HUMAN	Calcium-binding and coiled-coil domain-containing protein 2	12869526	HCC-associated protein HCAP1, a variant of GEMIN4, interacts with zinc-finger proteins.

P63165	SUMO1_HUMAN	Small ubiquitin-related modifier 1	8806687	PIC 1, a novel ubiquitin-like protein which interacts with the PML component of a multiprotein complex that is disrupted in acute promyelocytic leukaemia.

O43493	TGON2_HUMAN	Trans-Golgi network integral membrane protein 2	9422759	Molecular cloning and expression of a novel human trans-Golgi network glycoprotein, TGN51, that contains multiple tyrosine-containing motifs.

P38262	SIF2_YEAST	SIR4-interacting protein SIF2	11711434	The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program.

P49703	ARL4D_HUMAN	ADP-ribosylation factor-like protein 4D	7590735	Isolation and mapping of a gene encoding a novel human ADP- ribosylation factor on chromosome 17q12-q21.

P70056	FOXH1_XENLA	Forkhead box protein H1	8878477	A transcriptional partner for MAD proteins in TGF-beta signalling.

P69853	DMSD_ECOLI	Twin-arginine leader-binding protein dmsD	11309116	Identification of a twin-arginine leader-binding protein.

P08572	CO4A2_HUMAN	Collagen alpha-2(IV) chain	8317999	Identification of a novel sequence element in the common promoter region of human collagen type IV genes, involved in the regulation of divergent transcription.

O75445	USH2A_HUMAN	Usherin	16434480	The DFNB31 gene product whirlin connects to the Usher protein network in the cochlea and retina by direct association with USH2A and VLGR1.

Q32SG5	RIK_MAIZE	Protein RIK	16243907	Maize rough sheath2 and its Arabidopsis orthologue ASYMMETRIC LEAVES1 interact with HIRA, a predicted histone chaperone, to maintain knox gene silencing and determinacy during organogenesis.

P30305	MPIP2_HUMAN	M-phase inducer phosphatase 2	9188863	Alternative splicing of the human CDC25B tyrosine phosphatase. Possible implications for growth control?

O00192	ARVC_HUMAN	Armadillo repeat protein deleted in velo-cardio-facial syndrome	19706687	PDZ-domain-directed basolateral targeting of the peripheral membrane protein FRMPD2 in epithelial cells.

Q12055	KAD6_YEAST	Putative adenylate kinase FAP7	16287850	The putative NTPase Fap7 mediates cytoplasmic 20S pre-rRNA processing through a direct interaction with Rps14.

Q02888	AIM43_YEAST	Altered inheritance of mitochondria protein 43, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q06839	YP097_YEAST	PX domain-containing protein YPR097W	11557775	All phox homology (PX) domains from Saccharomyces cerevisiae specifically recognize phosphatidylinositol 3-phosphate.

Q9P7M8	NU184_SCHPO	Nucleoporin nup184	10388805	Regulation of mRNA export by nutritional status in fission yeast.

Q8BKT2	HES7_MOUSE	Transcription factor HES-7	15170214	Instability of Hes7 protein is crucial for the somite segmentation clock.

Q39172	P1_ARATH	Probable NADP-dependent oxidoreductase P1	7592828	Arabidopsis thaliana NADPH oxidoreductase homologs confer tolerance of yeasts toward the thiol-oxidizing drug diamide.

Q96FV9	THOC1_HUMAN	THO complex subunit 1	17190602	Human mRNA export machinery recruited to the 5' end of mRNA.

P38858	SOL3_YEAST	6-phosphogluconolactonase 3	15454531	Division of labor among the yeast Sol proteins implicated in tRNA nuclear export and carbohydrate metabolism.

Q9ERA6	TFP11_MOUSE	Tuftelin-interacting protein 11	11063033	Identification of tuftelin- and amelogenin-interacting proteins using the yeast two-hybrid system.

O44342	WBL_DROME	Protein windbeutel	9568717	Localized requirements for windbeutel and pipe reveal a dorsoventral prepattern within the follicular epithelium of the Drosophila ovary.

Q9BPX3	CND3_HUMAN	Condensin complex subunit 3	10910072	Serological cloning of a melanocyte rab guanosine 5'-triphosphate- binding protein and a chromosome condensation protein from a melanoma complementary DNA library.

P37261	FRM2_YEAST	Fatty acid repression mutant protein 2	8701605	Identification of a class of Saccharomyces cerevisiae mutants defective in fatty acid repression of gene transcription and analysis of the frm2 gene.

P35689	ERCC5_MOUSE	DNA repair protein complementing XP-G cells homolog	8703115	Molecular cloning and structural analysis of the functional mouse genomic XPG gene.

P53125	ITC1_YEAST	Imitation switch two complex protein 1	14673157	Noncompetitive counteractions of DNA polymerase epsilon and ISW2/yCHRAC for epigenetic inheritance of telomere position effect in Saccharomyces cerevisiae.

Q9SYK4	IP5PD_ARATH	Type I inositol-1,4,5-trisphosphate 5-phosphatase 13	16299182	At5PTase13 modulates cotyledon vein development through regulating auxin homeostasis.

O14924	RGS12_HUMAN	Regulator of G-protein signaling 12	9651375	GTPase activating specificity of RGS12 and binding specificity of an alternatively spliced PDZ (PSD-95/Dlg/ZO-1) domain.

P0AFZ5	SULA_ECOLI	Cell division inhibitor sulA	8752322	Interaction between FtsZ and inhibitors of cell division.

Q9JM05	PIAS4_MOUSE	E3 SUMO-protein ligase PIAS4	11731474	PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies.

Q9NXF7	DCA16_HUMAN	DDB1- and CUL4-associated factor 16	16949367	A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1.

Q08581	SLK19_YEAST	Kinetochore protein SLK19	15282802	Localization of proteins that are coordinately expressed with Cln2 during the cell cycle.

Q7KTX8	MED13_DROME	Mediator of RNA polymerase II transcription subunit 13	11090137	Drosophila homologs of transcriptional mediator complex subunits are required for adult cell and segment identity specification.

Q9WTJ4	FIZ1_MOUSE	Flt3-interacting zinc finger protein 1	10409713	Fiz1, a novel zinc finger protein interacting with the receptor tyrosine kinase Flt3.

Q15047	SETB1_HUMAN	Histone-lysine N-methyltransferase SETDB1	16682412	The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells.

O46043	PARG_DROME	Poly(ADP-ribose) glycohydrolase	14676324	Loss of poly(ADP-ribose) glycohydrolase causes progressive neurodegeneration in Drosophila melanogaster.

P15693	PPBI1_RAT	Intestinal-type alkaline phosphatase 1	7744844	Two rat intestinal alkaline phosphatase isoforms with different carboxyl-terminal peptides are both membrane-bound by a glycan phosphatidylinositol linkage.

Q86DA5	SARM1_CAEEL	Sterile alpha and TIR motif-containing protein tir-1	15123841	Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response.

Q14134	TRI29_HUMAN	Tripartite motif-containing protein 29	8188213	Nucleotide sequence analysis of a candidate gene for ataxia- telangiectasia group D (ATDC).

P52073	GLCE_ECOLI	Glycolate oxidase subunit glcE	8606183	glc locus of Escherichia coli: characterization of genes encoding the subunits of glycolate oxidase and the glc regulator protein.

Q06265	EXOS9_HUMAN	Exosome complex exonuclease RRP45	2007859	Molecular characterization of an autoantigen of PM-Scl in the polymyositis/scleroderma overlap syndrome: a unique and complete human cDNA encoding an apparent 75-kD acidic protein of the nucleolar complex.

O04379	AGO1_ARATH	Protein argonaute	9427751	AGO1 defines a novel locus of Arabidopsis controlling leaf development.

Q9Y7T9	YCJD_SCHPO	Uncharacterized J domain-containing protein C63.13	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O13790	CUL1_SCHPO	Cullin-1	11809834	Fission yeast F-box protein Pof3 is required for genome integrity and telomere function.

O88201	CLC11_RAT	C-type lectin domain family 11 member A	9705843	Isolation and characterization of a cDNA for human, mouse, and rat full-length stem cell growth factor, a new member of C-type lectin superfamily.

P46959	TRM61_YEAST	tRNA (adenine-N(1)-)-methyltransferase catalytic subunit TRM61	10779558	The Gcd10p/Gcd14p complex is the essential two-subunit tRNA(1- methyladenosine) methyltransferase of Saccharomyces cerevisiae.

O60513	B4GT4_HUMAN	Beta-1,4-galactosyltransferase 4	9792633	Cloning of a novel member of the UDP-galactose:beta-N- acetylglucosamine beta1,4-galactosyltransferase family, beta4Gal-T4, involved in glycosphingolipid biosynthesis.

Q06160	SPH1_YEAST	Protein SPH1	15282802	Localization of proteins that are coordinately expressed with Cln2 during the cell cycle.

P39108	PEX7_YEAST	Peroxisomal targeting signal 2 receptor	7957058	PAS7 encodes a novel yeast member of the WD-40 protein family essential for import of 3-oxoacyl-CoA thiolase, a PTS2-containing protein, into peroxisomes.

Q9GZT5	WN10A_HUMAN	Protein Wnt-10a	19559398	WNT10A mutations are a frequent cause of a broad spectrum of ectodermal dysplasias with sex-biased manifestation pattern in heterozygotes.

P52799	EFNB2_HUMAN	Ephrin-B2	8559144	Isolation of LERK-5: a ligand of the eph-related receptor tyrosine kinases.

P45577	PROQ_ECOLI	ProP effector	10049386	Protein ProQ influences osmotic activation of compatible solute transporter ProP in Escherichia coli K-12.

Q9H9P8	L2HDH_HUMAN	L-2-hydroxyglutarate dehydrogenase, mitochondrial	16005139	The gene mutated in L-2-hydroxyglutaric aciduria encodes L-2- hydroxyglutarate dehydrogenase.

O13834	PTR1_SCHPO	E3 ubiquitin-protein ligase ptr1	15094387	The fission yeast ptr1+ gene involved in nuclear mRNA export encodes a putative ubiquitin ligase.

P06780	RHO1_YEAST	GTP-binding protein RHO1	11591390	Functional characterization of the Bag7, Lrg1 and Rgd2 RhoGAP proteins from Saccharomyces cerevisiae.

Q8IYV9	IZUM1_HUMAN	Izumo sperm-egg fusion protein 1	15759005	The immunoglobulin superfamily protein Izumo is required for sperm to fuse with eggs.

Q13506	NAB1_HUMAN	NGFI-A-binding protein 1	8668170	NAB2, a corepressor of NGFI-A (Egr-1) and Krox20, is induced by proliferative and differentiative stimuli.

Q80Z19	MUC2_MOUSE	Mucin-2	11872843	Colorectal cancer in mice genetically deficient in the mucin Muc2.

Q8WWM9	CYGB_HUMAN	Cytoglobin	11919282	Cytoglobin: a novel globin type ubiquitously expressed in vertebrate tissues.

Q20646	CEP1_CAEEL	Transcription factor cep-1	17895432	Reduced expression of the Caenorhabditis elegans p53 ortholog cep-1 results in increased longevity.

P50224	ST1A3_HUMAN	Sulfotransferase 1A3/1A4	8117269	Human liver thermolabile phenol sulfotransferase: cDNA cloning, expression and characterization.

P35070	BTC_HUMAN	Probetacellulin	8439318	Cloning and expression of cDNA encoding human betacellulin, a new member of the EGF family.

Q60935	NAR1_MOUSE	GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1	8704249	Molecular characterization of a glycosylphosphatidylinositol-linked ADP-ribosyltransferase from lymphocytes.

Q9C107	MCL1_SCHPO	Minichromosome loss protein 1	16997270	Fission yeast Mcl1 interacts with SCF(Pof3) and is required for centromere formation.

P20967	ODO1_YEAST	2-oxoglutarate dehydrogenase, mitochondrial	11926067	Identification of the YMN-1 antigen protein and biochemical analyses of protein components in the mitochondrial nucleoid fraction of the yeast Saccharomyces cerevisiae.

Q96VH4	HBN1_YEAST	Putative nitroreductase HBN1	14562095	Global analysis of protein localization in budding yeast.

Q9BYB4	GNB1L_HUMAN	Guanine nucleotide-binding protein subunit beta-like protein 1	11072084	GNB1L, a gene deleted in the critical region for DiGeorge syndrome on 22q11, encodes a G-protein beta-subunit-like polypeptide.

Q15572	TAF1C_HUMAN	TATA box-binding protein-associated factor RNA polymerase I subunit C	7801123	Reconstitution of transcription factor SL1: exclusive binding of TBP by SL1 or TFIID subunits.

Q14353	GAMT_HUMAN	Guanidinoacetate N-methyltransferase	8547310	Cloning and sequence analysis of human guanidinoacetate N- methyltransferase cDNA.

Q9HCH5	SYTL2_HUMAN	Synaptotagmin-like protein 2	17182843	Exophilin4/Slp2-a targets glucagon granules to the plasma membrane through unique Ca2+-inhibitory phospholipid-binding activity of the C2A domain.

P23369	RM25_YEAST	54S ribosomal protein L25, mitochondrial	12392552	Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components.

Q5NCQ5	DPH1_MOUSE	Diphthamide biosynthesis protein 1	14744934	Ovca1 regulates cell proliferation, embryonic development, and tumorigenesis.

Q90999	TGFR2_CHICK	TGF-beta receptor type-2	8167376	Cloning and developmental expression of the chick type II and type III TGF beta receptors.

P01708	LV205_HUMAN	Ig lambda chain V-II region BUR	113407	Primary structure of a human IgA1 immunoglobulin. V. Amino acid sequence of a human IgA lambda light chain (Bur).

P25269	TRBP2_ARATH	Tryptophan synthase beta chain 2, chloroplastic	1840915	Tryptophan mutants in Arabidopsis: the consequences of duplicated tryptophan synthase beta genes.

Q62623	CDC20_RAT	Cell division cycle protein 20 homolog	7513050	A novel mammalian protein, p55CDC, present in dividing cells is associated with protein kinase activity and has homology to the Saccharomyces cerevisiae cell division cycle proteins Cdc20 and Cdc4.

Q02592	HMT1_SCHPO	Heavy metal tolerance protein	1396551	Heavy metal tolerance in the fission yeast requires an ATP-binding cassette-type vacuolar membrane transporter.

Q15046	SYK_HUMAN	Lysyl-tRNA synthetase	9278442	Human lysyl-tRNA synthetase accepts nucleotide 73 variants and rescues Escherichia coli double-defective mutant.

P09960	LKHA4_HUMAN	Leukotriene A-4 hydrolase	11175901	Crystal structure of human leukotriene A(4) hydrolase, a bifunctional enzyme in inflammation.

P60211	KA181_TITCA	Potassium channel toxin alpha-KTx 18.1	12445473	Two novel toxins from the Amazonian scorpion Tityus cambridgei that block Kv1.3 and Shaker B K(+)-channels with distinctly different affinities.

P61086	UBE2K_HUMAN	Ubiquitin-conjugating enzyme E2 K	16714285	NARF, an nemo-like kinase (NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF).

P07169	VIRBB_AGRT5	Protein virB11	3448462	Nucleotide sequence of the virG locus of the Agrobacterium tumefaciens plasmid pTiC58.

P41819	DIM1_YEAST	Dimethyladenosine transferase	8064863	The DIM1 gene responsible for the conserved m6(2)Am6(2)A dimethylation in the 3'-terminal loop of 18 S rRNA is essential in yeast.

P53174	PRM8_YEAST	Pheromone-regulated membrane protein 8	12101299	Functional analysis of the Saccharomyces cerevisiae DUP240 multigene family reveals membrane-associated proteins that are not essential for cell viability.

P0ABE2	BOLA_ECOLI	Protein BolA	12354237	The gene bolA regulates dacA (PBP5), dacC (PBP6) and ampC (AmpC), promoting normal morphology in Escherichia coli.

Q9Y7K1	YGL4_SCHPO	Uncharacterized protein C216.04c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9XTB5	LEM2_CAEEL	LEM protein 2	10982402	C. elegans nuclear envelope proteins emerin, MAN1, lamin, and nucleoporins reveal unique timing of nuclear envelope breakdown during mitosis.

O43061	MU136_SCHPO	Meiotically up-regulated gene 136 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9BX66	SRBS1_HUMAN	Sorbin and SH3 domain-containing protein 1	11371513	Ataxin-7 interacts with a Cbl-associated protein that it recruits into neuronal intranuclear inclusions.

Q12230	LSP1_YEAST	Sphingolipid long chain base-responsive protein LSP1	15016821	Pil1p and Lsp1p negatively regulate the 3-phosphoinositide-dependent protein kinase-like kinase Pkh1p and downstream signaling pathways Pkc1p and Ypk1p.

P62330	ARF6_HUMAN	ADP-ribosylation factor 6	17030804	Structural basis for Rab11-dependent membrane recruitment of a family of Rab11-interacting protein 3 (FIP3)/Arfophilin-1.

Q9ZP54	PARP1_ARATH	Poly [ADP-ribose] polymerase 1	11523787	Ionising radiation induces the expression of PARP-1 and PARP-2 genes in Arabidopsis.

D0ZPH9	SSPH2_SALT1	E3 ubiquitin-protein ligase sspH2	10861017	A conserved amino acid sequence directing intracellular type III secretion by Salmonella typhimurium.

Q8IZQ1	WDFY3_HUMAN	WD repeat and FYVE domain-containing protein 3	15292400	Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes.

Q9NZI8	IF2B1_HUMAN	Insulin-like growth factor 2 mRNA-binding protein 1	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

Q9W303	IDGF4_DROME	Chitinase-like protein Idgf4	9847235	A new family of growth factors produced by the fat body and active on Drosophila imaginal disc cells.

Q9JHB5	TSNAX_RAT	Translin-associated protein X	9681436	Identification of translin and trax as components of the GS1 strand- specific DNA binding complex enriched in brain.

P30793	GCH1_HUMAN	GTP cyclohydrolase 1	17101830	Novel mutations in the guanosine triphosphate cyclohydrolase 1 gene associated with DYT5 dystonia.

P02706	ASGR1_RAT	Asialoglycoprotein receptor 1	2995379	Characterization of the gene encoding the major rat liver asialoglycoprotein receptor.

Q10135	LSD2_SCHPO	Lysine-specific histone demethylase 2	17434129	S. pombe LSD1 homologs regulate heterochromatin propagation and euchromatic gene transcription.

Q8WW38	FOG2_HUMAN	Zinc finger protein ZFPM2	10438528	hFOG-2, a novel zinc finger protein, binds the co-repressor mCtBP2 and modulates GATA-mediated activation.

O54833	CSK22_MOUSE	Casein kinase II subunit alpha'	9694889	Protein kinase CK2alpha' is induced by serum as a delayed early gene and cooperates with Ha-ras in fibroblast transformation.

P35228	NOS2_HUMAN	Nitric oxide synthase, inducible	7504305	Cloning, characterization, and expression of a cDNA encoding an inducible nitric oxide synthase from the human chondrocyte.

Q6DCQ1	IRX2_XENLA	Iroquois-class homeodomain protein irx-2	12385755	Xiro homeoproteins coordinate cell cycle exit and primary neuron formation by upregulating neuronal-fate repressors and downregulating the cell-cycle inhibitor XGadd45-gamma.

Q9QWG5	INP4B_RAT	Type II inositol-3,4-bisphosphate 4-phosphatase	9295334	The cDNA cloning and characterization of inositol polyphosphate 4- phosphatase type II. Evidence for conserved alternative splicing in the 4-phosphatase family.

P38629	RFC3_YEAST	Replication factor C subunit 3	12665596	Mechanical link between cohesion establishment and DNA replication: Ctf7p/Eco1p, a cohesion establishment factor, associates with three different replication factor C complexes.

A2RSY6	TRM1L_MOUSE	TRM1-like protein	17198746	The mouse Trm1-like gene is expressed in neural tissues and plays a role in motor coordination and exploratory behaviour.

O49505	NCED2_ARATH	9-cis-epoxycarotenoid dioxygenase NCED2, chloroplastic	12834401	Molecular characterization of the Arabidopsis 9-cis epoxycarotenoid dioxygenase gene family.

P40072	SLX8_YEAST	E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX8	17848550	The yeast Hex3.Slx8 heterodimer is a ubiquitin ligase stimulated by substrate sumoylation.

Q9BZP6	CHIA_HUMAN	Acidic mammalian chitinase	10548734	Isolation and mapping of a human lung-specific gene, TSA1902, encoding a novel chitinase family member.

P86411	RGPA2_RAT	Ral GTPase-activating protein subunit alpha-2	19520869	Tuberous sclerosis tumor suppressor complex-like complexes act as GTPase-activating proteins for Ral GTPases.

Q08558	DCI1_YEAST	Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase	10455114	Alternatives to the isomerase-dependent pathway for the beta- oxidation of oleic acid are dispensable in Saccharomyces cerevisiae. Identification of YOR180c/DCI1 encoding peroxisomal delta(3,5)- delta(2,4)-dienoyl-CoA isomerase.

P0C0S1	MSCS_ECOLI	Small-conductance mechanosensitive channel	10202137	Protection of Escherichia coli cells against extreme turgor by activation of MscS and MscL mechanosensitive channels: identification of genes required for MscS activity.

P32368	SAC1_YEAST	Phosphoinositide phosphatase SAC1	10625610	SAC1 encodes a regulated lipid phosphoinositide phosphatase, defects in which can be suppressed by the homologous Inp52p and Inp53p phosphatases.

Q9USV3	SPF27_SCHPO	Pre-mRNA-splicing factor spf27	11884590	Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

O70608	SYCP2_RAT	Synaptonemal complex protein 2	9592139	SCP2: a major protein component of the axial elements of synaptonemal complexes of the rat.

Q9NPF0	CD320_HUMAN	CD320 antigen	10727470	Identification of a human follicular dendritic cell molecule that stimulates germinal center B cell growth.

P22301	IL10_HUMAN	Interleukin-10	9405662	Identification of functional domains on human interleukin 10.

Q9VXY7	LSD2_DROME	Lipid storage droplets surface-binding protein 2	12077142	Functional conservation for lipid storage droplet association among Perilipin, ADRP, and TIP47 (PAT)-related proteins in mammals, Drosophila, and Dictyostelium.

P17516	AK1C4_HUMAN	Aldo-keto reductase family 1 member C4	11158055	Human types 1 and 3 3 alpha-hydroxysteroid dehydrogenases: differential lability and tissue distribution.

O64380	PABP3_ARATH	Polyadenylate-binding protein 3	11516954	Analysis of an essential requirement for the poly(A) binding protein function using cross-species complementation.

P43115	PE2R3_HUMAN	Prostaglandin E2 receptor EP3 subtype	9073510	Structural organization of the human prostaglandin EP3 receptor subtype gene (PTGER3).

Q923I8	CRY2_RAT	Cryptochrome-2	11804325	Cloning and expression of cryptochrome2 cDNA in the rat.

Q96FM1	PGAP3_HUMAN	Post-GPI attachment to proteins factor 3	12460457	Identification of the CAB2/hCOS16 gene required for the repair of DNA double-strand breaks on a core amplified region of the 17q12 locus in breast and gastric cancers.

Q91XJ0	CREST_RAT	Calcium-responsive transcription coactivator	14716005	Dendrite development regulated by CREST, a calcium-regulated transcriptional activator.

Q96P20	NALP3_HUMAN	NACHT, LRR and PYD domains-containing protein 3	15030775	NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder.

P41797	HSP71_CANAL	Heat shock protein SSA1	7744244	Cloning of a DNA fragment encoding part of a 70-kDa heat shock protein of Candida albicans.

O95371	OR2C1_HUMAN	Olfactory receptor 2C1	9847080	Construction of an approximately 700-kb transcript map around the familial Mediterranean fever locus on human chromosome 16p13.3.

P41811	COPB2_YEAST	Coatomer subunit beta'	7929113	Yeast beta- and beta'-coat proteins (COP). Two coatomer subunits essential for endoplasmic reticulum-to-Golgi protein traffic.

P60842	IF4A1_HUMAN	Eukaryotic initiation factor 4A-I	9548260	Interaction of polyadenylate-binding protein with the eIF4G homologue PAIP enhances translation.

Q03518	TAP1_HUMAN	Antigen peptide transporter 1	8955196	Multiple regions of the transporter associated with antigen processing (TAP) contribute to its peptide binding site.

Q7KBL8	MED29_DROME	Mediator of RNA polymerase II transcription subunit 29	12361959	Intersex, a gene required for female sexual development in Drosophila, is expressed in both sexes and functions together with doublesex to regulate terminal differentiation.

P39706	SWD1_YEAST	COMPASS component SWD1	11687631	COMPASS: a complex of proteins associated with a trithorax-related SET domain protein.

Q96AW1	VOPP1_HUMAN	Vesicular, overexpressed in cancer, prosurvival protein 1	12761501	Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.

C0LGD7	Y1684_ARATH	Probable LRR receptor-like serine/threonine-protein kinase At1g06840	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q6AW69	CGNL1_MOUSE	Cingulin-like protein 1	15292197	JACOP, a novel plaque protein localizing at the apical junctional complex with sequence similarity to cingulin.

Q4Z8K6	RBP9X_DROME	Ran-binding proteins 9/10 homolog	18762575	RanBPM regulates cell shape, arrangement, and capacity of the female germline stem cell niche in Drosophila melanogaster.

Q9R0P9	UCHL1_MOUSE	Ubiquitin carboxyl-terminal hydrolase isozyme L1	12913066	Ubiquitin carboxy-terminal hydrolase L1 binds to and stabilizes monoubiquitin in neuron.

Q60813	ADM1A_MOUSE	Disintegrin and metalloproteinase domain-containing protein 1a	8146185	A family of cellular proteins related to snake venom disintegrins.

P97799	NRSN1_MOUSE	Neurensin-1	16527258	Molecular characterization of a transport vesicle protein Neurensin- 2, a homologue of Neurensin-1, expressed in neural cells.

Q10479	ALG8_SCHPO	Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P47108	URB2_YEAST	Nucleolar pre-ribosomal-associated protein 2	14562095	Global analysis of protein localization in budding yeast.

P26200	PROF2_DICDI	Profilin-2	15908944	The Diaphanous-related formin dDia2 is required for the formation and maintenance of filopodia.

Q9QXP0	RHCG_MOUSE	Ammonium transporter Rh type C	12388412	Localization of the ammonium transporter proteins RhBG and RhCG in mouse kidney.

Q99PD7	NCKX3_MOUSE	Sodium/potassium/calcium exchanger 3	11294880	Molecular cloning of a third member of the potassium-dependent sodium-calcium exchanger gene family, NCKX3.

P48994	TRPL_DROME	Transient-receptor-potential-like protein	10908615	Metabolic stress reversibly activates the Drosophila light-sensitive channels TRP and TRPL in vivo.

Q9P287	BCCIP_HUMAN	BRCA2 and CDKN1A-interacting protein	18440304	LYRIC/AEG-1 overexpression modulates BCCIPalpha protein levels in prostate tumor cells.

Q09793	NUP45_SCHPO	Nucleoporin nup45	15116432	Identification of genes encoding putative nucleoporins and transport factors in the fission yeast Schizosaccharomyces pombe: a deletion analysis.

P42845	STB1_YEAST	Protein STB1	10409718	Regulation of transcription at the Saccharomyces cerevisiae start transition by Stb1, a Swi6-binding protein.

P48570	HOSC_YEAST	Homocitrate synthase, cytosolic isozyme	8923736	Identification of a gene encoding a homocitrate synthase isoenzyme of Saccharomyces cerevisiae.

P45148	CAN_HAEIN	Carbonic anhydrase 2	16584170	Identification of a novel noncatalytic bicarbonate binding site in eubacterial beta-carbonic anhydrase.

P86409	RGPA1_PIG	Ral GTPase-activating protein subunit alpha-1	19520869	Tuberous sclerosis tumor suppressor complex-like complexes act as GTPase-activating proteins for Ral GTPases.

Q15648	MED1_HUMAN	Mediator of RNA polymerase II transcription subunit 1	10235266	Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex.

P69451	LCFA_ECOLI	Long-chain-fatty-acid--CoA ligase	1460045	Cloning, sequencing, and expression of the fadD gene of Escherichia coli encoding acyl coenzyme A synthetase.

P42528	ARP3_DICDI	Actin-related protein 3	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P69488	CUTA_ECOLI	Divalent-cation tolerance protein cutA	12949080	The evolutionarily conserved trimeric structure of CutA1 proteins suggests a role in signal transduction.

Q66K74	MAP1S_HUMAN	Microtubule-associated protein 1S	17658481	The NMDAR subunit NR3A interacts with microtubule-associated protein 1S in the brain.

P27099	TCBD_PSESQ	Chloromuconate cycloisomerase	2013566	Sequence analysis of the Pseudomonas sp. strain P51 tcb gene cluster, which encodes metabolism of chlorinated catechols: evidence for specialization of catechol 1,2-dioxygenases for chlorinated substrates.

O14867	BACH1_HUMAN	Transcription regulator protein BACH1	9544839	Isolation of the human BACH1 transcription regulator gene, which maps to chromosome 21q22.1.

P49683	PRLHR_HUMAN	Prolactin-releasing peptide receptor	8666380	Cloning and chromosomal mapping of three novel genes, GPR9, GPR10, and GPR14, encoding receptors related to interleukin 8, neuropeptide Y, and somatostatin receptors.

P24530	EDNRB_HUMAN	Endothelin B receptor	1713452	Cloning and functional expression of human cDNA for the ETB endothelin receptor.

P51153	RAB13_HUMAN	Ras-related protein Rab-13	8294494	A small rab GTPase is distributed in cytoplasmic vesicles in non polarized cells but colocalizes with the tight junction marker ZO-1 in polarized epithelial cells.

P25356	BPH1_YEAST	Beige protein homolog 1	15296494	Bph1p, the Saccharomyces cerevisiae homologue of CHS1/beige, functions in cell wall formation and protein sorting.

P43619	NADC_YEAST	Nicotinate-nucleotide pyrophosphorylase [carboxylating]	14562095	Global analysis of protein localization in budding yeast.

Q96NN9	AIFM3_HUMAN	Apoptosis-inducing factor 3	15764604	Molecular cloning and characterization of a human AIF-like gene with ability to induce apoptosis.

Q91Z62	FBX32_RAT	F-box only protein 32	11679633	Identification of ubiquitin ligases required for skeletal muscle atrophy.

P16499	PDE6A_HUMAN	Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha	7493036	Autosomal recessive retinitis pigmentosa caused by mutations in the alpha subunit of rod cGMP phosphodiesterase.

P24524	GLRA3_RAT	Glycine receptor subunit alpha-3	2176214	Identification and functional expression of a novel ligand binding subunit of the inhibitory glycine receptor.

Q61371	IFT88_MOUSE	Intraflagellar transport protein 88 homolog	11062270	Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella.

P79987	HIRA_CHICK	Protein HIRA	16537536	Asf1 is required for viability and chromatin assembly during DNA replication in vertebrate cells.

Q9UMS5	PHTF1_HUMAN	Putative homeodomain transcription factor 1	10729229	Molecular characterization of a novel gene family (PHTF) conserved from Drosophila to mammals.

Q9NRB3	CHSTC_HUMAN	Carbohydrate sulfotransferase 12	10781601	Molecular cloning and expression of two distinct human chondroitin 4- O-sulfotransferases that belong to the HNK-1 sulfotransferase gene family.

Q9BX66	SRBS1_HUMAN	Sorbin and SH3 domain-containing protein 1	11374898	Cloning, mapping, and characterization of the human sorbin and SH3 domain containing 1 (SORBS1) gene: a protein associated with c-Abl during insulin signaling in the hepatoma cell line Hep3B.

P82874	TO203_ARATH	Mitochondrial import receptor subunit TOM20-3	11161051	Purification and characterization of the preprotein translocase of the outer mitochondrial membrane from Arabidopsis. Identification of multiple forms of TOM20.

Q9NPH0	PPA6_HUMAN	Lysophosphatidic acid phosphatase type 6	10506173	Isolation of a cDNA encoding human lysophosphatidic acid phosphatase that is involved in the regulation of mitochondrial lipid biosynthesis.

P21243	PSA6_YEAST	Proteasome component C7-alpha	9087403	Structure of 20S proteasome from yeast at 2.4-A resolution.

P0A6A3	ACKA_ECOLI	Acetate kinase	2536666	Cloning, expression, and nucleotide sequence of the Escherichia coli K-12 ackA gene.

P23560	BDNF_HUMAN	Brain-derived neurotrophic factor	7703225	Structure of the brain-derived neurotrophic factor/neurotrophin 3 heterodimer.

Q9QZZ6	DERM_MOUSE	Dermatopontin	14980498	Cloning of murine early quiescence-1 gene: the murine counterpart of dermatopontin gene can induce and be induced by cell quiescence.

P69425	TATB_ECOLI	Sec-independent protein translocase protein tatB	11279240	TatB and TatC form a functional and structural unit of the twin- arginine translocase from Escherichia coli.

Q96K83	ZN521_HUMAN	Zinc finger protein 521	11984006	The Chediak-Higashi protein interacts with SNARE complex and signal transduction proteins.

Q9Y2U2	KCNK7_HUMAN	Potassium channel subfamily K member 7	10206991	Cloning of a new mouse two-P domain channel subunit and a human homologue with a unique pore structure.

P32377	MVD1_YEAST	Diphosphomevalonate decarboxylase	9244250	The Saccharomyces cerevisiae mevalonate diphosphate decarboxylase is essential for viability, and a single Leu-to-Pro mutation in a conserved sequence leads to thermosensitivity.

P49739	MCM3M_XENLA	Maternal DNA replication licensing factor mcm3	7760937	Purification of an MCM-containing complex as a component of the DNA replication licensing system.

O13897	YF36_SCHPO	Uncharacterized hydrolase C22A12.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P23367	MUTL_ECOLI	DNA mismatch repair protein mutL	9827806	Crystal structure and ATPase activity of MutL: implications for DNA repair and mutagenesis.

Q9UIK4	DAPK2_HUMAN	Death-associated protein kinase 2	10629061	Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis.

Q13795	ARFRP_HUMAN	ADP-ribosylation factor-related protein 1	8530503	ARP is a plasma membrane-associated Ras-related GTPase with remote similarity to the family of ADP-ribosylation factors.

P34119	PSA4_DICDI	Proteasome subunit alpha type-4	8130037	Proteasomes from Dictyostelium discoideum: characterization of structure and function.

Q8IUD2	RB6I2_HUMAN	ELKS/Rab6-interacting/CAST family member 1	12923177	Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins.

Q14749	GNMT_HUMAN	Glycine N-methyltransferase	10843803	Genomic structure, expression, and chromosomal localization of the human glycine N-methyltransferase gene.

Q8IFJ8	HCYB_SCUCO	Hemocyanin subunit B	12823556	Complete subunit sequences, structure and evolution of the 6 x 6-mer hemocyanin from the common house centipede, Scutigera coleoptrata.

Q9Y0T2	FBXA_DICDI	F-box/WD repeat-containing protein A	12796307	Genetic interactions of the E3 ubiquitin ligase component FbxA with cyclic AMP metabolism and a histidine kinase signaling pathway during Dictyostelium discoideum development.

P53615	CAN_YEAST	Carbonic anhydrase	15813743	The gene NCE103 (YNL036w) from Saccharomyces cerevisiae encodes a functional carbonic anhydrase and its transcription is regulated by the concentration of inorganic carbon in the medium.

P0ACC7	GLMU_ECOLI	Bifunctional protein glmU	8083170	Copurification of glucosamine-1-phosphate acetyltransferase and N- acetylglucosamine-1-phosphate uridyltransferase activities of Escherichia coli: characterization of the glmU gene product as a bifunctional enzyme catalyzing two subsequent steps in the pathway for UDP-N-acetylglucosamine synthesis.

P29622	KAIN_HUMAN	Kallistatin	1334488	Kallistatin: a novel human tissue kallikrein inhibitor. Purification, characterization, and reactive center sequence.

Q8N4T0	CBPA6_HUMAN	Carboxypeptidase A6	11836249	Identification and characterization of three members of the human metallocarboxypeptidase gene family.

Q99504	EYA3_HUMAN	Eyes absent homolog 3	9020840	A human homologue of the Drosophila eyes absent gene underlies branchio-oto-renal (BOR) syndrome and identifies a novel gene family.

Q8MY12	MHCKC_DICDI	Myosin heavy chain kinase C	15987738	Multiple myosin II heavy chain kinases: roles in filament assembly control and proper cytokinesis in Dictyostelium.

Q9UL63	MKLN1_HUMAN	Muskelin	10640805	cDNA cloning of human muskelin and localisation of the muskelin (MKLN1) gene to human chromosome 7q32 and mouse chromosome 6 B1/B2 by physical mapping and FISH.

Q9W1B0	GEK_DROME	Serine/threonine-protein kinase Genghis Khan	9371783	Genghis Khan (Gek) as a putative effector for Drosophila Cdc42 and regulator of actin polymerization.

O74309	SLM9_SCHPO	Histone transcription regulator slm9	10835386	Slm9, a novel nuclear protein involved in mitotic control in fission yeast.

Q54Z54	FTSZA_DICDI	Mitochondrial division protein fszA	14665465	Two Dictyostelium orthologs of the prokaryotic cell division protein FtsZ localize to mitochondria and are required for the maintenance of normal mitochondrial morphology.

Q9Z2M4	DECR2_RAT	Peroxisomal 2,4-dienoyl-CoA reductase	10333503	Identification of peroxisomal proteins by using M13 phage protein VI phage display: molecular evidence that mammalian peroxisomes contain a 2,4-dienoyl-CoA reductase.

Q9Z336	DYLT1_RAT	Dynein light chain Tctex-type 1	15992542	The dynein light chain Tctex-1 has a dynein-independent role in actin remodeling during neurite outgrowth.

Q9HDY1	ASE1_SCHPO	Anaphase spindle elongation protein 1	15647375	The roles of fission yeast ase1 in mitotic cell division, meiotic nuclear oscillation, and cytokinesis checkpoint signaling.

P34233	ASH1_YEAST	Transcriptional regulatory protein ASH1	9566907	Ash1, a daughter cell-specific protein, is required for pseudohyphal growth of Saccharomyces cerevisiae.

Q9FME8	OPT4_ARATH	Oligopeptide transporter 4	11788749	An oligopeptide transporter gene family in Arabidopsis.

Q10235	ALP11_SCHPO	Cell polarity protein alp11	10473641	Functional dissection and hierarchy of tubulin-folding cofactor homologues in fission yeast.

Q6WRH9	IGS10_RAT	Immunoglobulin superfamily member 10	14962803	CMF608 -- a novel mechanical strain-induced bone-specific protein expressed in early osteochondroprogenitor cells.

Q02388	CO7A1_HUMAN	Collagen alpha-1(VII) chain	8170945	Dominant dystrophic epidermolysis bullosa: identification of a Gly-->Ser substitution in the triple-helical domain of type VII collagen.

P01123	YPT1_YEAST	GTP-binding protein YPT1	3311726	Biochemical properties of the ras-related YPT protein in yeast: a mutational analysis.

Q9SUR3	RTNLA_ARATH	Reticulon-like protein B1	15060130	Identification of new intrinsic proteins in Arabidopsis plasma membrane proteome.

Q08AG7	MZT1_HUMAN	Mitotic-spindle organizing protein 1	20360068	Systematic analysis of human protein complexes identifies chromosome segregation proteins.

O76062	ERG24_HUMAN	Delta(14)-sterol reductase	9878250	The human lamin B receptor/sterol reductase multigene family.

Q99395	YP229_YEAST	Uncharacterized protein YPL229W	14562095	Global analysis of protein localization in budding yeast.

O35716	SOCS1_MOUSE	Suppressor of cytokine signaling 1	9889194	Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction.

P56159	GFRA1_HUMAN	GDNF family receptor alpha-1	9545641	Human GFRA1: cloning, mapping, genomic structure, and evaluation as a candidate gene for Hirschsprung disease susceptibility.

O75154	RFIP3_HUMAN	Rab11 family-interacting protein 3	18511905	Sequential Cyk-4 binding to ECT2 and FIP3 regulates cleavage furrow ingression and abscission during cytokinesis.

P38801	LRP1_YEAST	Exosome complex protein LRP1	12972615	Rrp47p is an exosome-associated protein required for the 3' processing of stable RNAs.

Q9HBA0	TRPV4_HUMAN	Transient receptor potential cation channel subfamily V member 4	12724311	Ca2+-dependent potentiation of the nonselective cation channel TRPV4 is mediated by a C-terminal calmodulin binding site.

Q9FHA2	ALC_ARATH	Transcription factor ALC	11747817	The Arabidopsis myc/bHLH gene ALCATRAZ enables cell separation in fruit dehiscence.

P70196	TRAF6_MOUSE	TNF receptor-associated factor 6	10215628	TRAF6 deficiency results in osteopetrosis and defective interleukin- 1, CD40, and LPS signaling.

P0A9K9	SLYD_ECOLI	FKBP-type peptidyl-prolyl cis-trans isomerase slyD	15569666	A role for SlyD in the Escherichia coli hydrogenase biosynthetic pathway.

Q21898	VATL1_CAEEL	V-type proton ATPase 16 kDa proteolipid subunit 1	9305897	Three vha genes encode proteolipids of Caenorhabditis elegans vacuolar-type ATPase. Gene structures and preferential expression in an H-shaped excretory cell and rectal cells.

Q27395	LI15B_CAEEL	Protein lin-15B	8054684	The lin-15 locus encodes two negative regulators of Caenorhabditis elegans vulval development.

Q9LD43	ACCA_ARATH	Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, chloroplastic	15028209	The Arabidopsis thaliana chloroplast proteome reveals pathway abundance and novel protein functions.

Q86UE6	LRRT1_HUMAN	Leucine-rich repeat transmembrane neuronal protein 1	17667961	LRRTM1 on chromosome 2p12 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia.

O01427	AIR2_CAEEL	Aurora/IPL1-related protein kinase 2	11050384	The aurora-related kinase AIR-2 recruits ZEN-4/CeMKLP1 to the mitotic spindle at metaphase and is required for cytokinesis.

Q8R3G1	PP1R8_MOUSE	Nuclear inhibitor of protein phosphatase 1	15199142	The nuclear scaffold protein NIPP1 is essential for early embryonic development and cell proliferation.

Q8TEQ6	GEMI5_HUMAN	Gem-associated protein 5	11714716	Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins.

Q9VEI3	S35B2_DROME	Adenosine 3'-phospho 5'-phosphosulfate transporter 1	12853478	Slalom encodes an adenosine 3'-phosphate 5'-phosphosulfate transporter essential for development in Drosophila.

Q00055	GPD1_YEAST	Glycerol-3-phosphate dehydrogenase [NAD+] 1	15210723	Distinct intracellular localization of Gpd1p and Gpd2p, the two yeast isoforms of NAD+-dependent glycerol-3-phosphate dehydrogenase, explains their different contributions to redox-driven glycerol production.

Q9NYV8	T2R14_HUMAN	Taste receptor type 2 member 14	10761934	A novel family of mammalian taste receptors.

Q6P6T4	EMAL2_RAT	Echinoderm microtubule-associated protein-like 2	11829466	Identification of rat EMAP, a delta-glutamate receptor binding protein.

P85211	LEB1_GALME	Lebocin-like anionic peptide 1	17194500	Purification and characterization of eight peptides from Galleria mellonella immune hemolymph.

Q53EK2	NSE1_SCHPO	Non-structural maintenance of chromosomes element 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q08605	GAGA_DROME	Transcription factor GAGA	12834867	Trl-GAGA directly interacts with lola like and both are part of the repressive complex of Polycomb group of genes.

Q96BR1	SGK3_HUMAN	Serine/threonine-protein kinase Sgk3	10548550	Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase.

P32082	GHRHR_MOUSE	Growth hormone-releasing hormone receptor	8391647	Molecular basis of the little mouse phenotype and implications for cell type-specific growth.

Q80T11	USH1G_MOUSE	Usher syndrome type-1G protein homolog	12588794	Usher syndrome type I G (USH1G) is caused by mutations in the gene encoding SANS, a protein that associates with the USH1C protein, harmonin.

Q95YE9	CLK2_CAEEL	Telomere length regulation protein clk-2	11641227	The C. elegans maternal-effect gene clk-2 is essential for embryonic development, encodes a protein homologous to yeast Tel2p and affects telomere length.

O35132	CP27B_RAT	25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	9371776	Cloning and expression of rat 25-hydroxyvitamin D3-1alpha-hydroxylase cDNA.

P49004	DPOD2_BOVIN	DNA polymerase delta subunit 2	10751307	Identification of a fourth subunit of mammalian DNA polymerase delta.

P36394	SRY_RAT	Sex-determining region Y protein	16904257	The poly(ADP-ribose) polymerase 1 interacts with Sry and modulates its biological functions.

Q8BIL5	HOOK1_MOUSE	Protein Hook homolog 1	12075009	The Hook1 gene is non-functional in the abnormal spermatozoon head shape (azh) mutant mouse.

P21275	BMP4_MOUSE	Bone morphogenetic protein 4	17472960	Repulsive guidance molecule RGMa alters utilization of bone morphogenetic protein (BMP) type II receptors by BMP2 and BMP4.

Q9BRR9	RHG09_HUMAN	Rho GTPase-activating protein 9	11396949	Isolation of a novel human gene, ARHGAP9, encoding a rho-GTPase activating protein.

P38844	DSE2_YEAST	Protein DSE2	11935221	Sequence-based approach for identification of cell wall proteins in Saccharomyces cerevisiae.

Q9PU41	CCKN_CHICK	Cholecystokinin	8355559	Effects of cholecystokinin and gastrin on gastroduodenal motility and coordination in chickens.

Q80Z64	NANOG_MOUSE	Homeobox protein NANOG	12787505	Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells.

Q9HAU4	SMUF2_HUMAN	E3 ubiquitin-protein ligase SMURF2	14755250	An RNF11: Smurf2 complex mediates ubiquitination of the AMSH protein.

O74792	SNF59_SCHPO	SWI/SNF global transcription activator complex subunit snf59	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P36027	MID2_YEAST	Cell wall integrity sensor MID2	16087742	The Rgd1p Rho GTPase-activating protein and the Mid2p cell wall sensor are required at low pH for protein kinase C pathway activation and cell survival in Saccharomyces cerevisiae.

P07092	GDN_RAT	Glia-derived nexin	3427015	cDNA sequence coding for a rat glia-derived nexin and its homology to members of the serpin superfamily.

Q93W20	NIFU2_ARATH	NifU-like protein 2, chloroplastic	12553879	Iron-sulphur cluster assembly in plants: distinct NFU proteins in mitochondria and plastids from Arabidopsis thaliana.

P40565	IST3_YEAST	U2 snRNP component IST3	11287609	A novel yeast U2 snRNP protein, Snu17p, is required for the first catalytic step of splicing and for progression of spliceosome assembly.

P03973	SLPI_HUMAN	Antileukoproteinase	3485543	The acid-stable proteinase inhibitor of human mucous secretions (HUSI-I, antileukoprotease). Complete amino acid sequence as revealed by protein and cDNA sequencing and structural homology to whey proteins and Red sea turtle proteinase inhibitor.

P11310	ACADM_HUMAN	Medium-chain specific acyl-CoA dehydrogenase, mitochondrial	1902818	Molecular characterization of medium-chain acyl-CoA dehydrogenase (MCAD) deficiency: identification of a lys329 to glu mutation in the MCAD gene, and expression of inactive mutant enzyme protein in E. coli.

P46934	NEDD4_HUMAN	E3 ubiquitin-protein ligase NEDD4	17218260	NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN.

Q13233	M3K1_HUMAN	Mitogen-activated protein kinase kinase kinase 1	9808624	JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extension.

Q8TBA6	GOGA5_HUMAN	Golgin subfamily A member 5	12538640	The coiled-coil membrane protein golgin-84 is a novel rab effector required for Golgi ribbon formation.

Q99KG7	HPS4_MOUSE	Hermansky-Pudlak syndrome 4 protein homolog	11836498	Hermansky-Pudlak syndrome is caused by mutations in HPS4, the human homolog of the mouse light-ear gene.

Q9Y703	TBCA_SCHPO	Tubulin-specific chaperone A	10978278	The cofactor-dependent pathways for alpha- and beta-tubulins in microtubule biogenesis are functionally different in fission yeast.

Q13591	SEM5A_HUMAN	Semaphorin-5A	9464278	Molecular cloning and mapping of human semaphorin F from the Cri-du- chat candidate interval.

Q04323	UBXN1_HUMAN	UBX domain-containing protein 1	20351172	The UBXN1 protein associates with autoubiquitinated forms of the BRCA1 tumor suppressor and inhibits its enzymatic function.

Q6IRK9	PGCP_RAT	Plasma glutamate carboxypeptidase	12390252	lal-1: a differentially expressed novel gene during proliferation in liver regeneration and in hepatoma cells.

P21693	DBPA_ECOLI	ATP-independent RNA helicase dbpA	9016593	Characterization of DbpA, an Escherichia coli DEAD box protein with ATP independent RNA unwinding activity.

P29340	UBCX_YEAST	Ubiquitin-conjugating enzyme E2-21 kDa	17550898	A conserved cysteine is essential for Pex4p-dependent ubiquitination of the peroxisomal import receptor Pex5p.

P36132	KAE1_YEAST	Putative glycoprotein endopeptidase KAE1	16874308	Yeast homolog of a cancer-testis antigen defines a new transcription complex.

O13853	ITS3_SCHPO	Phosphatidylinositol-4-phosphate 5-kinase its3	10950958	Phosphatidylinositol 4-phosphate 5-kinase Its3 and calcineurin Ppb1 coordinately regulate cytokinesis in fission yeast.

P53104	ATG1_YEAST	Serine/threonine-protein kinase ATG1	9190802	AUT3, a serine/threonine kinase gene, is essential for autophagocytosis in Saccharomyces cerevisiae.

P49597	P2C56_ARATH	Protein phosphatase 2C 56	8492808	Abscisic acid-insensitive mutations provide evidence for stage- specific signal pathways regulating expression of an Arabidopsis late embryogenesis-abundant (lea) gene.

Q92521	PIGB_HUMAN	GPI mannosyltransferase 3	8861954	PIG-B, a membrane protein of the endoplasmic reticulum with a large lumenal domain, is involved in transferring the third mannose of the GPI anchor.

Q9Y253	POLH_HUMAN	DNA polymerase eta	10398605	hRAD30 mutations in the variant form of xeroderma pigmentosum.

Q8VWG3	TT1_ARATH	Protein TRANSPARENT TESTA 1	11782451	A. thaliana TRANSPARENT TESTA 1 is involved in seed coat development and defines the WIP subfamily of plant zinc finger proteins.

P49653	P2RX2_RAT	P2X purinoceptor 2	7542879	Identification of a short form of the P2xR1-purinoceptor subunit produced by alternative splicing in the pituitary and cochlea.

Q9NQC7	CYLD_HUMAN	Ubiquitin carboxyl-terminal hydrolase CYLD	18636086	The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response.

P15731	UBC4_YEAST	Ubiquitin-conjugating enzyme E2 4	2154373	Ubiquitin-conjugating enzymes UBC4 and UBC5 mediate selective degradation of short-lived and abnormal proteins.

Q24185	HOOK_DROME	Protein hook	9927460	Genetic analysis of hook, a gene required for endocytic trafficking in Drosophila.

P11458	NADA_ECOLI	Quinolinate synthase A	2841129	Molecular biology of pyridine nucleotide biosynthesis in Escherichia coli. Cloning and characterization of quinolinate synthesis genes nadA and nadB.

Q15274	NADC_HUMAN	Nicotinate-nucleotide pyrophosphorylase [carboxylating]	9473669	Characterization and functional expression of the cDNA encoding human brain quinolinate phosphoribosyltransferase.

P02647	APOA1_HUMAN	Apolipoprotein A-I	11991719	Cloning and characterization of a novel apolipoprotein A-I-binding protein, AI-BP, secreted by cells of the kidney proximal tubules in response to HDL or ApoA-I.

Q9JK11	RTN4_RAT	Reticulon-4	10231557	Cloning and characterization of a 22 kDa protein from rat adipocytes: a new member of the reticulon family.

P35348	ADA1A_HUMAN	Alpha-1A adrenergic receptor	8396931	Cloning, functional expression and tissue distribution of human cDNA for the alpha 1C-adrenergic receptor.

P10070	GLI2_HUMAN	Zinc finger protein GLI2	9557682	Cloning of novel isoforms of the human Gli2 oncogene and their activities to enhance tax-dependent transcription of the human T-cell leukemia virus type 1 genome.

Q13571	LAPM5_HUMAN	Lysosomal-associated transmembrane protein 5	8661146	LAPTM5: a novel lysosomal-associated multispanning membrane protein preferentially expressed in hematopoietic cells.

Q47377	ARNE_ECOLI	Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE	17928292	An undecaprenyl phosphate-aminoarabinose flippase required for polymyxin resistance in Escherichia coli.

Q12929	EPS8_HUMAN	Epidermal growth factor receptor kinase substrate 8	15289329	IRSp53/Eps8 complex is important for positive regulation of Rac and cancer cell motility/invasiveness.

Q99013	ANPB_PSEAM	Ice-structuring protein B	3769927	Biosynthesis of antifreeze polypeptides in the winter flounder. Characterization and seasonal occurrence of precursor polypeptides.

Q9H902	REEP1_HUMAN	Receptor expression-enhancing protein 1	15550249	RTP family members induce functional expression of mammalian odorant receptors.

P08243	ASNS_HUMAN	Asparagine synthetase [glutamine-hydrolyzing]	2886907	Isolation of human cDNAs for asparagine synthetase and expression in Jensen rat sarcoma cells.

P42208	SEPT2_MOUSE	Septin-2	9203580	Nedd5, a mammalian septin, is a novel cytoskeletal component interacting with actin-based structures.

P38426	TPS3_YEAST	Trehalose synthase complex regulatory subunit TPS3	9194697	Structural analysis of the subunits of the trehalose-6-phosphate synthase/phosphatase complex in Saccharomyces cerevisiae and their function during heat shock.

P50995	ANX11_HUMAN	Annexin A11	15197175	Annexin 11 is required for midbody formation and completion of the terminal phase of cytokinesis.

A1EGX6	FSCB_MOUSE	Fibrous sheath CABYR-binding protein	17855365	FSCB, a novel protein kinase A-phosphorylated calcium-binding protein, is a CABYR-binding partner involved in late steps of fibrous sheath biogenesis.

P35575	G6PC_HUMAN	Glucose-6-phosphatase	8211187	Mutations in the glucose-6-phosphatase gene that cause glycogen storage disease type 1a.

Q14032	BAAT_HUMAN	Bile acid-CoA:amino acid N-acyltransferase	2037576	Purification and characterization of bile acid-CoA:amino acid N- acyltransferase from human liver.

O88343	S4A4_MOUSE	Electrogenic sodium bicarbonate cotransporter 1	9651366	Molecular cloning, chromosomal localization, tissue distribution, and functional expression of the human pancreatic sodium bicarbonate cotransporter.

P25586	KRR1_YEAST	Ribosomal RNA assembly protein KRR1	11027267	Yeast Krr1p physically and functionally interacts with a novel essential Kri1p, and both proteins are required for 40S ribosome biogenesis in the nucleolus.

P06213	INSR_HUMAN	Insulin receptor	8276809	Direct activation of the phosphatidylinositol 3'-kinase by the insulin receptor.

Q9W1X4	NU214_DROME	Nuclear pore complex protein Nup214	14638854	The Drosophila nucleoporin DNup88 localizes DNup214 and CRM1 on the nuclear envelope and attenuates NES-mediated nuclear export.

P38920	MLH1_YEAST	DNA mismatch repair protein MLH1	10938116	Functional studies on the candidate ATPase domains of Saccharomyces cerevisiae MutLalpha.

Q14739	LBR_HUMAN	Lamin-B receptor	8157662	Primary structure analysis and lamin B and DNA binding of human LBR, an integral protein of the nuclear envelope inner membrane.

P36012	CENPA_YEAST	Histone H3-like centromeric protein CSE4	7698647	A mutation in CSE4, an essential gene encoding a novel chromatin- associated protein in yeast, causes chromosome nondisjunction and cell cycle arrest at mitosis.

Q15907	RB11B_HUMAN	Ras-related protein Rab-11B	16545962	The crystal structure of the small GTPase Rab11b reveals critical differences relative to the Rab11a isoform.

Q9Y2I6	NINL_HUMAN	Ninein-like protein	12852856	Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation.

P35465	PAK1_RAT	Serine/threonine-protein kinase PAK 1	14707132	Characterization of OSR1, a member of the mammalian Ste20p/germinal center kinase subfamily.

Q8IU57	I28RA_HUMAN	Interleukin-28 receptor subunit alpha	12483210	IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex.

P54638	ARGE_DICDI	Acetylornithine deacetylase	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P06762	HMOX1_RAT	Heme oxygenase 1	3865203	Cloning and expression of cDNA for rat heme oxygenase.

P34220	YBF5_YEAST	Deoxyribonuclease Tat-D	14562095	Global analysis of protein localization in budding yeast.

Q02206	RSC4_YEAST	Chromatin structure-remodeling complex subunit RSC4	10619019	Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains.

P15919	RAG1_MOUSE	V(D)J recombination-activating protein 1	20122409	The RING domain of RAG1 ubiquitylates histone H3: a novel activity in chromatin-mediated regulation of V(D)J joining.

Q92527	ANKR7_HUMAN	Ankyrin repeat domain-containing protein 7	8812458	Isolation of three testis-specific genes (TSA303, TSA806, TSA903) by a differential mRNA display method.

Q3UWM4	KDM7_MOUSE	Lysine-specific demethylase 7	20194436	KDM7 is a dual demethylase for histone H3 Lys 9 and Lys 27 and functions in brain development.

Q13360	ZN177_HUMAN	Zinc finger protein 177	8661005	Transcripts from a novel human KRAB zinc finger gene contain spliced Alu and endogenous retroviral segments.

Q15131	CDK10_HUMAN	Cell division protein kinase 10	8084611	Molecular cloning of PISSLRE, a novel putative member of the cdk family of protein serine/threonine kinases.

Q08380	LG3BP_HUMAN	Galectin-3-binding protein	8034587	The secreted tumor-associated antigen 90K is a potent immune stimulator.

P14906	SEC63_YEAST	Protein translocation protein SEC63	7758110	Posttranslational protein transport in yeast reconstituted with a purified complex of Sec proteins and Kar2p.

Q9BU61	NDUF3_HUMAN	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3	19463981	Mutations in NDUFAF3 (C3ORF60), encoding an NDUFAF4 (C6ORF66)- interacting complex I assembly protein, cause fatal neonatal mitochondrial disease.

P53252	PIL1_YEAST	Sphingolipid long chain base-responsive protein PIL1	14562095	Global analysis of protein localization in budding yeast.

Q96S59	RANB9_HUMAN	Ran-binding protein 9	14500717	Serine/threonine kinase Mirk/Dyrk1B is an inhibitor of epithelial cell migration and is negatively regulated by the Met adaptor Ran- binding protein M.

Q9XYS3	NOXA_DICDI	Superoxide-generating NADPH oxidase heavy chain subunit A	15950752	NADPH oxidase homologs are required for normal cell differentiation and morphogenesis in Dictyostelium discoideum.

P35659	DEK_HUMAN	Protein DEK	12140263	Daxx and histone deacetylase II associate with chromatin through an interaction with core histones and the chromatin-associated protein Dek.

Q9UPY3	DICER_HUMAN	Endoribonuclease Dicer	17452327	Human TRBP and PACT directly interact with each other and associate with dicer to facilitate the production of small interfering RNA.

Q9V427	INX2_DROME	Innexin inx2	10352230	Drosophila has several genes for gap junction proteins.

Q9UGH3	S23A2_HUMAN	Solute carrier family 23 member 2	9804989	Molecular characterization of two novel transporters from human and mouse kidney and from LLC-PK1 cells reveals a novel conserved family that is homologous to bacterial and Aspergillus nucleobase transporters.

Q9BT25	HAUS8_HUMAN	HAUS augmin-like complex subunit 8	19427217	HAUS, the 8-subunit human augmin complex, regulates centrosome and spindle integrity.

P43699	NKX21_HUMAN	Homeobox protein Nkx-2.1	11854319	Choreoathetosis, hypothyroidism, and pulmonary alterations due to human NKX2-1 haploinsufficiency.

P53621	COPA_HUMAN	Coatomer subunit alpha	1429581	Identification of xenin, a xenopsin-related peptide, in the human gastric mucosa and its effect on exocrine pancreatic secretion.

Q558Z2	SUN1_DICDI	Sun domain-containing protein 1	18266910	Dictyostelium Sun-1 connects the centrosome to chromatin and ensures genome stability.

P07560	SEC4_YEAST	Ras-related protein SEC4	11785952	Saccharomyces cerevisiae Pra1p/Yip3p interacts with Yip1p and Rab proteins.

P15367	SEC11_YEAST	Signal peptidase complex catalytic subunit SEC11	3283143	SEC11 is required for signal peptide processing and yeast cell growth.

Q8CBD1	NRIP1_MOUSE	Nuclear receptor-interacting protein 1	15155905	Nuclear receptor corepressor RIP140 regulates fat accumulation.

P79083	EIF3I_SCHPO	Eukaryotic translation initiation factor 3 subunit I	9560390	Sum1, a highly conserved WD-repeat protein, suppresses S-M checkpoint mutants and inhibits the osmotic stress cell cycle response in fission yeast.

Q6PEH4	DEF_DANRE	Digestive organ expansion factor	16322560	Loss of function of def selectively up-regulates Delta113p53 expression to arrest expansion growth of digestive organs in zebrafish.

Q9JKT2	TR119_MOUSE	Taste receptor type 2 member 119	10761934	A novel family of mammalian taste receptors.

Q62829	PAK3_RAT	Serine/threonine-protein kinase PAK 3	7559638	Molecular cloning of a new member of the p21-Cdc42/Rac-activated kinase (PAK) family.

Q94554	ER_DROVI	Protein enhancer of rudimentary	7896098	Enhancer of rudimentaryp1, e(r)p1, a highly conserved enhancer of the rudimentary gene.

P17106	CBF1_YEAST	Centromere-binding protein 1	2185892	Yeast centromere binding protein CBF1, of the helix-loop-helix protein family, is required for chromosome stability and methionine prototrophy.

O04616	Y4115_ARATH	Uncharacterized protein At4g01150, chloroplastic	16461379	Protein profiling of plastoglobules in chloroplasts and chromoplasts. A surprising site for differential accumulation of metabolic enzymes.

P14906	SEC63_YEAST	Protein translocation protein SEC63	12518317	Identification of novel protein-protein interactions at the cytosolic surface of the Sec63 complex in the yeast ER membrane.

Q9P6Q1	YKC9_SCHPO	UPF0001 protein C644.09	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q66K79	CBPZ_HUMAN	Carboxypeptidase Z	9099699	Cloning and expression of human carboxypeptidase Z, a novel metallocarboxypeptidase.

Q9UTI3	ARD1_SCHPO	N-terminal acetyltransferase A complex catalytic subunit ard1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q91765	FXA2A_XENLA	Forkhead box protein A2-A	7739038	DNA recognition site analysis of Xenopus winged helix proteins.

O42601	S17B1_XENLA	Transcription factor Sox-17-beta.1	16193513	SOX7 and SOX18 are essential for cardiogenesis in Xenopus.

Q9D3G9	RHOH_MOUSE	Rho-related GTP-binding protein RhoH	17119112	RhoH is important for positive thymocyte selection and T-cell receptor signaling.

Q9M7Q5	AI5L4_ARATH	ABSCISIC ACID-INSENSITIVE 5-like protein 4	10636868	ABFs, a family of ABA-responsive element binding factors.

P54687	BCAT1_HUMAN	Branched-chain-amino-acid aminotransferase, cytosolic	8692959	ECA39, a conserved gene regulated by c-Myc in mice, is involved in G1/S cell cycle regulation in yeast.

P35218	CAH5A_HUMAN	Carbonic anhydrase 5A, mitochondrial	8356065	Human mitochondrial carbonic anhydrase: cDNA cloning, expression, subcellular localization, and mapping to chromosome 16.

P53602	MVD1_HUMAN	Diphosphomevalonate decarboxylase	8626466	Molecular cloning and expression of the cDNAs encoding human and yeast mevalonate pyrophosphate decarboxylase.

O00570	SOX1_HUMAN	Transcription factor SOX-1	9337405	Cloning and mapping of the human SOX1: a highly conserved gene expressed in the developing brain.

P08670	VIME_HUMAN	Vimentin	19270731	The cellular distribution of serotonin transporter is impeded on serotonin-altered vimentin network.

O48946	CESA1_ARATH	Cellulose synthase A catalytic subunit 1 [UDP-forming]	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P70505	ADAM1_RAT	Disintegrin and metalloproteinase domain-containing protein 1	9358007	Cloning and sequence analysis of rat fertilin alpha and beta - developmental expression, processing and immunolocalization.

Q9JJP2	P73_MOUSE	Tumor protein p73	10716451	p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours.

Q05783	HMGD_DROME	High mobility group protein D	7720717	HMG-D is an architecture-specific protein that preferentially binds to DNA containing the dinucleotide TG.

Q8W4L5	VAL1_ARATH	B3 domain-containing transcription repressor VAL1	17267611	Two B3 domain transcriptional repressors prevent sugar-inducible expression of seed maturation genes in Arabidopsis seedlings.

O61967	LAP1_CAEEL	Protein lap1	14578922	Basolateral targeting by leucine-rich repeat domains in epithelial cells.

Q84TG3	PUB23_ARATH	E3 ubiquitin-protein ligase PUB23	18664614	Arabidopsis PUB22 and PUB23 are homologous U-Box E3 ubiquitin ligases that play combinatory roles in response to drought stress.

P38792	RRP4_YEAST	Exosome complex component RRP4	10465791	The yeast exosome and human PM-Scl are related complexes of 3'-->5' exonucleases.

O08590	AOC3_RAT	Membrane primary amine oxidase	9083076	Membrane amine oxidase cloning and identification as a major protein in the adipocyte plasma membrane.

Q8RWD9	ACBP5_ARATH	Acyl-CoA-binding domain-containing protein 5	19121948	An Arabidopsis family of six acyl-CoA-binding proteins has three cytosolic members.

P09661	RU2A_HUMAN	U2 small nuclear ribonucleoprotein A'	9716128	Crystal structure of the spliceosomal U2B'-U2A' protein complex bound to a fragment of U2 small nuclear RNA.

Q460M5	LRFN2_RAT	Leucine-rich repeat and fibronectin type-III domain-containing protein 2	16495444	A novel family of adhesion-like molecules that interacts with the NMDA receptor.

Q21067	IFC2_CAEEL	Intermediate filament protein ifc-2	11427699	Essential roles for four cytoplasmic intermediate filament proteins in Caenorhabditis elegans development.

P38428	CUE1_YEAST	Coupling of ubiquitin conjugation to ER degradation protein 1	9388185	Role of Cue1p in ubiquitination and degradation at the ER surface.

P25685	DNJB1_HUMAN	DnaJ homolog subfamily B member 1	8975727	Genomic cloning of a human heat shock protein 40 (Hsp40) gene (HSPF1) and its chromosomal localization to 19p13.2.

Q5RJY2	G2E3_MOUSE	G2/M phase-specific E3 ubiquitin-protein ligase	18511420	G2E3 is a dual function ubiquitin ligase required for early embryonic development.

P38687	SRP68_YEAST	Signal recognition particle subunit SRP68	7925282	Subunits of the Saccharomyces cerevisiae signal recognition particle required for its functional expression.

O95232	LC7L3_HUMAN	Luc7-like protein 3	10754390	Identification of okadaic-acid-induced genes by mRNA differential display in glioma cells.

Q9CS84	NRX1A_MOUSE	Neurexin-1-alpha	11243866	Synaptotagmin-like protein 1-3: a novel family of C-terminal-type tandem C2 proteins.

P32335	MSS51_YEAST	Protein MSS51, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q9LX49	PRN1_ARATH	Pirin-1	12837948	The Arabidopsis cupin domain protein AtPirin1 interacts with the G protein alpha-subunit GPA1 and regulates seed germination and early seedling development.

O94343	YHMA_SCHPO	Uncharacterized MFS-type transporter C1271.10c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P34125	DGKA_DICDI	Diacylglycerol kinase A	1321427	Membrane-bound Dictyostelium myosin heavy chain kinase: a developmentally regulated substrate-specific member of the protein kinase C family.

Q9DFS6	IF4EA_DANRE	Eukaryotic translation initiation factor 4E-1A	14701818	Two zebrafish eIF4E family members are differentially expressed and functionally divergent.

Q9SDM9	NSP1_ARATH	Nitrile-specifier protein 1	18987211	The genetic basis of constitutive and herbivore-induced ESP- independent nitrile formation in Arabidopsis.

O74444	MU122_SCHPO	Meiotically up-regulated gene 122 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P53492	ACT7_ARATH	Actin-7	8754679	The Arabidopsis ACT7 actin gene is expressed in rapidly developing tissues and responds to several external stimuli.

P24784	DBP1_YEAST	ATP-dependent RNA helicase DBP1	14562095	Global analysis of protein localization in budding yeast.

O76927	RS21_DROME	40S ribosomal protein S21	10022917	Down-regulation of RpS21, a putative translation initiation factor interacting with P40, produces viable minute imagos and larval lethality with overgrown hematopoietic organs and imaginal discs.

Q60795	NF2L2_MOUSE	Nuclear factor erythroid 2-related factor 2	11583586	Cloning and characterization of the mouse polyamine-modulated factor- 1 (mPMF-1) gene: an alternatively spliced homologue of the human transcription factor.

Q13443	ADAM9_HUMAN	Disintegrin and metalloproteinase domain-containing protein 9	12054541	A secreted form of human ADAM9 has an alpha-secretase activity for APP.

Q8BXL7	ARFRP_MOUSE	ADP-ribosylation factor-related protein 1	11839814	Embryonic lethality caused by apoptosis during gastrulation in mice lacking the gene of the ADP-ribosylation factor-related protein 1.

Q8RXD4	BRCA1_ARATH	Protein BREAST CANCER SUSCEPTIBILITY 1 homolog	12582233	Characterization of Arabidopsis thaliana ortholog of the human breast cancer susceptibility gene 1: AtBRCA1, strongly induced by gamma rays.

P53705	BUD4_CANAL	Bud site selection protein BUD4	16858141	Role of the septin Cdc10 in the virulence of Candida albicans.

P83691	GANA_HUMIN	Arabinogalactan endo-1,4-beta-galactosidase	12761390	Structure of two fungal beta-1,4-galactanases: searching for the basis for temperature and pH optimum.

Q61830	MRC1_MOUSE	Macrophage mannose receptor 1	1421407	Characterization of the murine macrophage mannose receptor: demonstration that the downregulation of receptor expression mediated by interferon-gamma occurs at the level of transcription.

Q9P212	PLCE1_HUMAN	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon-1	17086182	Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible.

Q11002	CANA_DROME	Calpain-A	7929201	Calpain localization changes in coordination with actin-related cytoskeletal changes during early embryonic development of Drosophila.

P28069	PIT1_HUMAN	Pituitary-specific positive transcription factor 1	1487156	Characterization of the gene encoding human pituitary-specific transcription factor, Pit-1.

Q01105	SET_HUMAN	Protein SET	8626647	The myeloid leukemia-associated protein SET is a potent inhibitor of protein phosphatase 2A.

Q05541	NSE3_YEAST	Non-structural maintenance of chromosome element 3	15738391	A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization.

P17443	MURG_ECOLI	UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase	1649817	The murG gene of Escherichia coli codes for the UDP-N- acetylglucosamine: N-acetylmuramyl-(pentapeptide) pyrophosphoryl- undecaprenol N-acetylglucosamine transferase involved in the membrane steps of peptidoglycan synthesis.

Q7TN83	SYT16_MOUSE	Synaptotagmin-16	12801916	Molecular cloning, expression, and characterization of a novel class of synaptotagmin (Syt XIV) conserved from Drosophila to humans.

Q8GZ38	UNE10_ARATH	Transcription factor UNE10	15634699	Genetic and molecular identification of genes required for female gametophyte development and function in Arabidopsis.

Q9NR55	BATF3_HUMAN	Basic leucine zipper transcriptional factor ATF-like 3	10878360	Repression of IL-2 promoter activity by the novel basic leucine zipper p21SNFT protein.

P47095	MTNB_YEAST	Methylthioribulose-1-phosphate dehydratase	14562095	Global analysis of protein localization in budding yeast.

Q9NRC9	OTOR_HUMAN	Otoraplin	10873378	A novel conserved cochlear gene, OTOR: identification, expression analysis, and chromosomal mapping.

Q9R0L6	PCM1_MOUSE	Pericentriolar material 1 protein	10579718	Centriolar satellites: molecular characterization, ATP-dependent movement toward centrioles and possible involvement in ciliogenesis.

P02643	TNNI2_RABIT	Troponin I, fast skeletal muscle	9560191	Crystal structure of troponin C in complex with troponin I fragment at 2.3-A resolution.

Q9Y7M6	RRP1_SCHPO	Ribosomal RNA-processing protein 1 homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q7T103	P5F11_XENLA	POU domain, class 5, transcription factor 1.1	17950579	The Xenopus POU class V transcription factor XOct-25 inhibits ectodermal competence to respond to bone morphogenetic protein- mediated embryonic induction.

O74853	FAP1H_SCHPO	FKBP12-associated protein 1 homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P40088	FTR1_YEAST	Plasma membrane iron permease	8599111	A permease-oxidase complex involved in high-affinity iron uptake in yeast.

P48199	CRP_RAT	C-reactive protein	1737750	Derivation of the amino acid sequence of rat C-reactive protein from cDNA cloning with additional studies on the nature of its dimeric component.

Q39110	GAOX1_ARATH	Gibberellin 20 oxidase 1	7604047	The GA5 locus of Arabidopsis thaliana encodes a multifunctional gibberellin 20-oxidase: molecular cloning and functional expression.

P50991	TCPD_HUMAN	T-complex protein 1 subunit delta	8626763	Identification of a group of cellular cofactors that stimulate the binding of RNA polymerase II and TRP-185 to human immunodeficiency virus 1 TAR RNA.

Q8WUF5	IASPP_HUMAN	RelA-associated inhibitor	10336463	Identification of a novel inhibitor of nuclear factor-kappaB, RelA- associated inhibitor.

Q12999	TSN31_HUMAN	Tetraspanin-31	8134123	SAS, a gene amplified in human sarcomas, encodes a new member of the transmembrane 4 superfamily of proteins.

P31150	GDIA_HUMAN	Rab GDP dissociation inhibitor alpha	7849400	Evolutionary conservation and genomic organization of XAP-4, an Xq28 located gene coding for a human rab GDP-dissociation inhibitor (GDI).

Q9UJX2	CDC23_HUMAN	Cell division cycle protein 23 homolog	9790767	Human CDC23: cDNA cloning, mapping to 5q31, genomic structure, and evaluation as a candidate tumor suppressor gene in myeloid leukemias.

P27472	GYS2_YEAST	Glycogen [starch] synthase isoform 2	1908457	Two glycogen synthase isoforms in Saccharomyces cerevisiae are coded by distinct genes that are differentially controlled.

P32389	MET4_YEAST	Transcriptional activator of sulfur metabolism MET4	9799240	Multiple transcriptional activation complexes tether the yeast activator Met4 to DNA.

Q9UQK1	PPR3C_HUMAN	Protein phosphatase 1 regulatory subunit 3C	8985175	Amino acid sequence of a novel protein phosphatase 1 binding protein (R5) which is related to the liver- and muscle-specific glycogen binding subunits of protein phosphatase 1.

P19139	CSK21_RAT	Casein kinase II subunit alpha	8173590	Cloning of cDNAs encoding the alpha and beta subunits of rat casein kinase 2 (CK-2): investigation of molecular regulation of CK-2 by androgens in rat ventral prostate.

P09884	DPOLA_HUMAN	DNA polymerase alpha catalytic subunit	2243771	Human DNA polymerase alpha catalytic polypeptide binds ConA and RCA and contains a specific labile site in the N-terminus.

Q8L5Y6	CAND1_ARATH	Cullin-associated NEDD8-dissociated protein 1	15181201	AtCAND1, a HEAT-repeat protein that participates in auxin signaling in Arabidopsis.

Q9LKL2	APRR1_ARATH	Two-component response regulator-like APRR1	10743655	Interactions of the developmental regulator ABI3 with proteins identified from developing Arabidopsis seeds.

P0ADA1	TESA_ECOLI	Acyl-CoA thioesterase I	1864840	Lysophospholipase L1 from Escherichia coli K-12 overproducer.

Q84WP6	NAC43_ARATH	NAC domain-containing protein 43	16214898	The NAC transcription factors NST1 and NST2 of Arabidopsis regulate secondary wall thickenings and are required for anther dehiscence.

Q8IU57	I28RA_HUMAN	Interleukin-28 receptor subunit alpha	12469119	IL-28, IL-29 and their class II cytokine receptor IL-28R.

Q9JKS6	PCLO_RAT	Protein piccolo	10707984	Piccolo, a presynaptic zinc finger protein structurally related to bassoon.

Q9U6Y9	ANM5_DROME	Protein arginine N-methyltransferase 5	18369183	Sm protein methylation is dispensable for snRNP assembly in Drosophila melanogaster.

P68767	AMPA_ECOLI	Cytosol aminopeptidase	2670557	xerB, an Escherichia coli gene required for plasmid ColE1 site- specific recombination, is identical to pepA, encoding aminopeptidase A, a protein with substantial similarity to bovine lens leucine aminopeptidase.

P38295	MCFS2_YEAST	Medium-chain fatty acid ethyl ester synthase/esterase 2	16361250	The Saccharomyces cerevisiae EHT1 and EEB1 genes encode novel enzymes with medium-chain fatty acid ethyl ester synthesis and hydrolysis capacity.

P50542	PEX5_HUMAN	Peroxisomal targeting signal 1 receptor	7719337	Mutations in the PTS1 receptor gene, PXR1, define complementation group 2 of the peroxisome biogenesis disorders.

Q3TPJ7	MIDN_MOUSE	Midnolin	10974535	Novel nucleolar protein, midnolin, is expressed in the mesencephalon during mouse development.

P07315	CRGC_HUMAN	Gamma-crystallin C	12011157	Novel mutations in the gamma-crystallin genes cause autosomal dominant congenital cataracts.

O75594	PGRP1_HUMAN	Peptidoglycan recognition protein 1	11461926	Peptidoglycan recognition proteins: a novel family of four human innate immunity pattern recognition molecules.

P51818	HSP83_ARATH	Heat shock protein 81-3	7697294	Analysis of tissue-specific expression of Arabidopsis thaliana HSP90- family gene HSP81.

P28288	ABCD3_HUMAN	ATP-binding cassette sub-family D member 3	10704444	PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis.

Q08537	UPK2_BOVIN	Uroplakin-2	12475947	Specific heterodimer formation is a prerequisite for uroplakins to exit from the endoplasmic reticulum.

Q03764	EKI1_YEAST	Ethanolamine kinase	10329685	Isolation and characterization of the Saccharomyces cerevisiae EKI1 gene encoding ethanolamine kinase.

P63324	RS12_RAT	40S ribosomal protein S12	3308890	The primary structure of rat ribosomal protein S12. The relationship of rat S12 to other ribosomal proteins and a correlation of the amino acid sequences of rat and yeast ribosomal proteins.

P19087	GNAT2_HUMAN	Guanine nucleotide-binding protein G(t) subunit alpha-2	2534964	Alpha transducin is present in blue-, green-, and red-sensitive cone photoreceptors in the human retina.

Q06630	MHR1_YEAST	Mitochondrial homologous recombination protein 1	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q07807	PUF3_YEAST	mRNA-binding protein PUF3	11101532	The Puf3 protein is a transcript-specific regulator of mRNA degradation in yeast.

P17719	DYR_DROME	Dihydrofolate reductase	14526388	The Drosophila wing differentiation factor vestigial-scalloped is required for cell proliferation and cell survival at the dorso-ventral boundary of the wing imaginal disc.

P20848	A1ATR_HUMAN	Putative alpha-1-antitrypsin-related protein	2842251	Molecular structure and sequence homology of a gene related to alpha 1-antitrypsin in the human genome.

Q6KC79	NIPBL_HUMAN	Nipped-B-like protein	15146185	NIPBL, encoding a homolog of fungal Scc2-type sister chromatid cohesion proteins and fly Nipped-B, is mutated in Cornelia de Lange syndrome.

O74653	POB1_SCHPO	Protein pob1	10436025	Fission yeast Pob1p, which is homologous to budding yeast boi proteins and exhibits subcellular localization close to actin patches, is essential for cell elongation and separation.

Q99497	PARK7_HUMAN	Protein DJ-1	9070310	DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras.

P32790	SLA1_YEAST	Actin cytoskeleton-regulatory complex protein SLA1	15651983	Lsb5p interacts with actin regulators Sla1p and Las17p, ubiquitin and Arf3p to couple actin dynamics to membrane trafficking processes.

O14193	MUG69_SCHPO	Meiotically up-regulated gene 69 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q08289	CACB2_HUMAN	Voltage-dependent L-type calcium channel subunit beta-2	9254841	Assignment of human genes for beta 2 and beta 4 subunits of voltage- dependent Ca2+ channels to chromosomes 10p12 and 2q22-q23.

O15527	OGG1_HUMAN	N-glycosylase/DNA lyase	9223305	Cloning and characterization of hOGG1, a human homolog of the OGG1 gene of Saccharomyces cerevisiae.

P53673	CRBA4_HUMAN	Beta-crystallin A4	16960806	CRYBA4, a novel human cataract gene, is also involved in microphthalmia.

P16104	H2AX_HUMAN	Histone H2A.x	12419185	NBS1 localizes to gamma-H2AX foci through interaction with the FHA/BRCT domain.

O43137	YB085_YEAST	Uncharacterized protein YBR085C-A	14562095	Global analysis of protein localization in budding yeast.

P12080	ITA2_DROME	Integrin alpha-PS2	2961459	The Drosophila PS2 antigen is an invertebrate integrin that, like the fibronectin receptor, becomes localized to muscle attachments.

Q9W349	LOZEN_DROME	Protein lozenge	15879554	Lozenge directly activates argos and klumpfuss to regulate programmed cell death.

O35188	X3CL1_MOUSE	Fractalkine	9177350	Neurotactin, a membrane-anchored chemokine upregulated in brain inflammation.

Q9LQZ0	PUP15_ARATH	Putative purine permease 15	10662864	A new family of high-affinity transporters for adenine, cytosine, and purine derivatives in Arabidopsis.

P19826	VINC_CAEEL	Vinculin	2498337	The basal component of the nematode dense-body is vinculin.

Q10142	AUR1_SCHPO	Inositol phosphorylceramide synthase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q14749	GNMT_HUMAN	Glycine N-methyltransferase	15340920	Glycine N-methyltransferases: a comparison of the crystal structures and kinetic properties of recombinant human, mouse and rat enzymes.

Q94A97	UBC35_ARATH	Ubiquitin-conjugating enzyme E2 35	16786304	Arabidopsis thaliana UBC13: implication of error-free DNA damage tolerance and Lys63-linked polyubiquitylation in plants.

O77783	EXT2_BOVIN	Exostosin-2	9756849	The putative tumor suppressors EXT1 and EXT2 are glycosyltransferases required for the biosynthesis of heparan sulfate.

Q924S5	LONM_RAT	Lon protease homolog, mitochondrial	15560797	Age-related impairment of mitochondrial matrix aconitase and ATP- stimulated protease in rat liver and heart.

O95390	GDF11_HUMAN	Growth/differentiation factor 11	10391213	Regulation of anterior/posterior patterning of the axial skeleton by growth/differentiation factor 11.

P53058	VEL1_YEAST	Protein VEL1	11935221	Sequence-based approach for identification of cell wall proteins in Saccharomyces cerevisiae.

O82794	AGL24_ARATH	MADS-box protein AGL24	18694458	AGAMOUS-LIKE24 and SHORT VEGETATIVE PHASE determine floral meristem identity in Arabidopsis.

P30728	DRD3_MOUSE	D(3) dopamine receptor	8449953	A novel short isoform of the D3 dopamine receptor generated by alternative splicing in the third cytoplasmic loop.

O94782	UBP1_HUMAN	Ubiquitin carboxyl-terminal hydrolase 1	18082604	A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway.

Q07930	PML1_YEAST	Pre-mRNA leakage protein 1	15565172	Proteomic analysis identifies a new complex required for nuclear pre- mRNA retention and splicing.

Q6B9X6	VWKA_DICDI	Alpha-protein kinase vwkA	15728726	Identification and characterization of a novel alpha-kinase with a von Willebrand factor A-like motif localized to the contractile vacuole and Golgi complex in Dictyostelium discoideum.

P52292	IMA2_HUMAN	Importin subunit alpha-2	7754385	Identification of hSRP1 alpha as a functional receptor for nuclear localization sequences.

P47158	CAF17_YEAST	Putative transferase CAF17, mitochondrial	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

P09543	CN37_HUMAN	2',3'-cyclic-nucleotide 3'-phosphodiesterase	8392017	Structure, expression and chromosomal localization of the gene encoding human 2',3'-cyclic-nucleotide 3'-phosphodiesterase.

Q9UKP3	ITBP2_HUMAN	Integrin beta-1-binding protein 2	10506186	Melusin is a new muscle-specific interactor for beta(1) integrin cytoplasmic domain.

P03979	TVC_HUMAN	T-cell receptor gamma chain V region PT-gamma-1/2	3458221	Cloning and sequence analysis of complementary DNA encoding an aberrantly rearranged human T-cell gamma chain.

P06100	NOT2_YEAST	General negative regulator of transcription subunit 2	7926748	NOT1(CDC39), NOT2(CDC36), NOT3, and NOT4 encode a global-negative regulator of transcription that differentially affects TATA-element utilization.

Q9SVD7	UEV1D_ARATH	Ubiquitin-conjugating enzyme E2 variant 1D	18178771	Arabidopsis UEV1D promotes lysine-63-linked polyubiquitination and is involved in DNA damage response.

P07355	ANXA2_HUMAN	Annexin A2	3013422	Two human 35 kd inhibitors of phospholipase A2 are related to substrates of pp60v-src and of the epidermal growth factor receptor/kinase.

Q9I7I0	CCNB3_DROME	G2/mitotic-specific cyclin-B3	11369230	The schedule of destruction of three mitotic cyclins can dictate the timing of events during exit from mitosis.

P23677	IP3KA_HUMAN	Inositol-trisphosphate 3-kinase A	1847047	Molecular cloning and expression of a human brain inositol 1,4,5- trisphosphate 3-kinase.

Q9GQV7	HPEP_AEDAE	Head peptide	11931033	Characterization of the AeaHP gene and its expression in the mosquito Aedes aegypti (Diptera: Culicidae).

Q13835	PKP1_HUMAN	Plakophilin-1	9326952	Mutations in the plakophilin 1 gene result in ectodermal dysplasia/skin fragility syndrome.

P12996	BIOB_ECOLI	Biotin synthase	17014080	Biotin synthase mechanism: mutagenesis of the YNHNLD conserved motif.

O74555	BBP_SCHPO	Branchpoint-bridging protein	12374752	Pre-spliceosome formation in S.pombe requires a stable complex of SF1-U2AF(59)-U2AF(23).

P53196	RPN14_YEAST	26S proteasome regulatory subunit RPN14	14562095	Global analysis of protein localization in budding yeast.

Q05513	KPCZ_HUMAN	Protein kinase C zeta type	11260256	Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42 to atypical protein kinase C.

Q9DBI0	TMPS6_MOUSE	Transmembrane protease serine 6	12744720	Mouse matriptase-2: identification, characterization and comparative mRNA expression analysis with mouse hepsin in adult and embryonic tissues.

Q00013	EM55_HUMAN	55 kDa erythrocyte membrane protein	17584769	MPP1 links the Usher protein network and the Crumbs protein complex in the retina.

P61758	PFD3_HUMAN	Prefoldin subunit 3	8674032	Identification of a novel protein (VBP-1) binding to the von Hippel- Lindau (VHL) tumor suppressor gene product.

P93024	ARFE_ARATH	Auxin response factor 5	17553903	AMP1 and MP antagonistically regulate embryo and meristem development in Arabidopsis.

Q8CHM7	HACL1_RAT	2-hydroxyacyl-CoA lyase 1	10468558	Purification, molecular cloning, and expression of 2- hydroxyphytanoyl-CoA lyase, a peroxisomal thiamine hydrophosphate- dependent enzyme that catalyzes the carbon-carbon bond cleavage during alpha-oxidation of 3-methyl-branched fatty acids.

P01608	KV116_HUMAN	Ig kappa chain V-I region Roy	5595110	Chemical structure of 2 kappa-type Bence Jones proteins (Roy and Cum.).

P53969	SAM50_YEAST	Sorting assembly machinery 50 kDa subunit	14685243	Evolutionary conservation of biogenesis of beta-barrel membrane proteins.

P41231	P2RY2_HUMAN	P2Y purinoceptor 2	8159738	Cloning and expression of a human P2U nucleotide receptor, a target for cystic fibrosis pharmacotherapy.

P32600	TOR2_YEAST	Serine/threonine-protein kinase TOR2	10198052	Regulation of ribosome biogenesis by the rapamycin-sensitive TOR- signaling pathway in Saccharomyces cerevisiae.

P22333	ADD_ECOLI	Adenosine deaminase	1998686	Deduced amino acid sequence of Escherichia coli adenosine deaminase reveals evolutionarily conserved amino acid residues: implications for catalytic function.

Q9LW57	PAP6_ARATH	Probable plastid-lipid-associated protein 6, chloroplastic	16414959	Tocopherol cyclase (VTE1) localization and vitamin E accumulation in chloroplast plastoglobule lipoprotein particles.

P87061	TEA1_SCHPO	Tip elongation aberrant protein 1	12034771	Roles of fission yeast tea1p in the localization of polarity factors and in organizing the microtubular cytoskeleton.

Q05164	HPF1_YEAST	Haze protective factor 1	11748726	Cooperative functions of the mannoprotein-encoding genes in the biogenesis and maintenance of the cell wall in Saccharomyces cerevisiae.

Q8R414	PROK1_RAT	Prokineticin-1	12054613	Isolation and identification of EG-VEGF/prokineticins as cognate ligands for two orphan G-protein-coupled receptors.

Q9M7Q2	AI5L7_ARATH	ABSCISIC ACID-INSENSITIVE 5-like protein 7	11005831	Arabidopsis basic leucine zipper transcription factors involved in an abscisic acid-dependent signal transduction pathway under drought and high-salinity conditions.

P50430	ARSB_RAT	Arylsulfatase B	8575749	Mucopolysaccharidosis type VI in rats: isolation of cDNAs encoding arylsulfatase B, chromosomal localization of the gene, and identification of the mutation.

Q9R109	OAZ3_MOUSE	Ornithine decarboxylase antizyme 3	15642376	Yeast two-hybrid screens imply that GGNBP1, GGNBP2 and OAZ3 are potential interaction partners of testicular germ cell-specific protein GGN1.

P21238	RUBA_ARATH	RuBisCO large subunit-binding protein subunit alpha, chloroplastic	11402200	The Arabidopsis embryo mutant schlepperless has a defect in the chaperonin-60alpha gene.

Q03833	GIS1_YEAST	Transcriptional activator/repressor GIS1	14562095	Global analysis of protein localization in budding yeast.

P84090	ERH_HUMAN	Enhancer of rudimentary homolog	8786099	Cloning and mapping of a novel human cDNA homologous to DROER, the enhancer of the Drosophila melanogaster rudimentary gene.

P34247	UTP11_YEAST	U3 small nucleolar RNA-associated protein 11	12068309	A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis.

P49333	ETR1_ARATH	Ethylene receptor 1	11916973	Localization of the ethylene receptor ETR1 to the endoplasmic reticulum of Arabidopsis.

Q96S38	KS6C1_HUMAN	Ribosomal protein S6 kinase delta-1	10552933	Cloning, characterization, and chromosome mapping of RPS6KC1, a novel putative member of the ribosome protein S6 kinase family, to chromosome 12q12-q13.1.

P68164	FER_DATME	Ferredoxin	7764481	Identical amino acid sequence of ferredoxin from Datura metel and D. innoxia.

Q9UBV2	SE1L1_HUMAN	Protein sel-1 homolog 1	19706418	A luminal flavoprotein in endoplasmic reticulum-associated degradation.

Q24523	BUN2_DROME	Protein bunched, class 2/F isoform	7555710	Shortsighted acts in the decapentaplegic pathway in Drosophila eye development and has homology to a mouse TGF-beta-responsive gene.

P97520	C5AR_RAT	C5a anaphylatoxin chemotactic receptor	9464523	Molecular cloning and expression of the functional rat C5a receptor.

Q8IIG1	YK213_PLAF7	Uncharacterized protein PF11_0213	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

O15303	GRM6_HUMAN	Metabotropic glutamate receptor 6	9215706	The whole nucleotide sequence and chromosomal localization of the gene for human metabotropic glutamate receptor subtype 6.

O75027	ABCB7_HUMAN	ATP-binding cassette sub-family B member 7, mitochondrial	10196363	Mutation of a putative mitochondrial iron transporter gene (ABC7) in X-linked sideroblastic anemia and ataxia (XLSA/A).

Q9WU42	NCOR2_MOUSE	Nuclear receptor corepressor 2	10077563	Unique forms of human and mouse nuclear receptor corepressor SMRT.

Q7TN38	MRGRH_RAT	Mas-related G-protein coupled receptor member H	12909716	Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family.

P23975	SC6A2_HUMAN	Sodium-dependent noradrenaline transporter	2008212	Expression cloning of a cocaine- and antidepressant-sensitive human noradrenaline transporter.

Q14186	TFDP1_HUMAN	Transcription factor Dp-1	8405995	Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation.

Q14626	I11RA_HUMAN	Interleukin-11 receptor subunit alpha	7670098	Molecular cloning of two isoforms of a receptor for the human hematopoietic cytokine interleukin-11.

P08074	CBR2_MOUSE	Carbonyl reductase [NADPH] 2	7705352	Cloning, expression and tissue distribution of mouse tetrameric carbonyl reductase. Identity with an adipocyte 27-kDa protein.

Q86U86	PB1_HUMAN	Protein polybromo-1	15985610	PBAF chromatin-remodeling complex requires a novel specificity subunit, BAF200, to regulate expression of selective interferon- responsive genes.

P77712	TESC_ECOLI	Long-chain acyl-CoA thioesterase tesC	18576672	Identification and characterization of Escherichia coli thioesterase III that functions in fatty acid beta-oxidation.

Q9UK96	FBX10_HUMAN	F-box only protein 10	10531035	Identification of a family of human F-box proteins.

P04913	H2B1_SCHPO	Histone H2B-alpha	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P60229	EIF3E_MOUSE	Eukaryotic translation initiation factor 3 subunit E	17581632	Reconstitution reveals the functional core of mammalian eIF3.

P08476	INHBA_HUMAN	Inhibin beta A chain	3267209	Erythroid differentiation factor is encoded by the same mRNA as that of the inhibin beta A chain.

P23946	CMA1_HUMAN	Chymase	2071582	Structure, chromosomal assignment, and deduced amino acid sequence of a human gene for mast cell chymase.

P29448	TRXH1_ARATH	Thioredoxin H1	16945919	Thioredoxin-h1 reduces and reactivates the oxidized cytosolic malate dehydrogenase dimer in higher plants.

O74983	MMS2_SCHPO	Ubiquitin-conjugating enzyme spm2	12531016	Structural and functional conservation of error-free DNA postreplication repair in Schizosaccharomyces pombe.

Q08268	MCH4_YEAST	Probable transporter MCH4	11536335	The putative monocarboxylate permeases of the yeast Saccharomyces cerevisiae do not transport monocarboxylic acids across the plasma membrane.

O60671	RAD1_HUMAN	Cell cycle checkpoint protein RAD1	10359610	The human G2 checkpoint control protein hRAD9 is a nuclear phosphoprotein that forms complexes with hRAD1 and hHUS1.

Q03758	BUL2_YEAST	Ubiquitin ligase-binding protein BUL2	14562095	Global analysis of protein localization in budding yeast.

Q7TSG3	FBX5_MOUSE	F-box only protein 5	16809773	Mouse emi1 has an essential function in mitotic progression during early embryogenesis.

O74964	RSC1_SCHPO	Chromatin structure-remodeling complex subunit rsc1	18622392	Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast.

P78898	TGCE2_SCHPO	Probable lipase C16A3.12c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9P7G3	YK45_SCHPO	UPF0136 membrane protein P14E8.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Y5Q8	TF3C5_HUMAN	General transcription factor 3C polypeptide 5	17409385	Identification, molecular cloning, and characterization of the sixth subunit of human transcription factor TFIIIC.

P35125	UBP6_HUMAN	Ubiquitin carboxyl-terminal hydrolase 6	12612085	The TRE17 oncogene encodes a component of a novel effector pathway for Rho GTPases Cdc42 and Rac1 and stimulates actin remodeling.

O70139	IPKG_MOUSE	cAMP-dependent protein kinase inhibitor gamma	9218452	Characterization of PKI-gamma, a novel isoform of the protein kinase inhibitor of cAMP-dependent protein kinase.

Q9VRJ0	GEN_DROME	Flap endonuclease GEN	15576351	DmGEN, a novel RAD2 family endo-exonuclease from Drosophila melanogaster.

Q8H110	XCT_ARATH	Protein XAP5 CIRCADIAN TIMEKEEPER	18515502	XAP5 CIRCADIAN TIMEKEEPER coordinates light signals for proper timing of photomorphogenesis and the circadian clock in Arabidopsis.

P38605	CAS1_ARATH	Cycloartenol synthase	18287026	Allelic mutant series reveal distinct functions for Arabidopsis cycloartenol synthase 1 in cell viability and plastid biogenesis.

Q5XK83	MCM4A_XENLA	DNA replication licensing factor mcm4-A	9214646	The RLF-M component of the replication licensing system forms complexes containing all six MCM/P1 polypeptides.

P32939	YPT7_YEAST	GTP-binding protein YPT7	12553664	A novel phospholipid-binding protein from the yeast Saccharomyces cerevisiae with dual binding specificities for the transport GTPase Ypt7p and the Sec1-related Vps33p.

Q8NI27	THOC2_HUMAN	THO complex subunit 2	15833825	Linking transcriptional elongation and messenger RNA export to metastatic breast cancers.

Q9H227	GBA3_HUMAN	Cytosolic beta-glucosidase	11389701	Cloning and characterization of human liver cytosolic beta- glycosidase.

Q8CGT6	PIWL4_MOUSE	Piwi-like protein 4	17395546	MIWI2 is essential for spermatogenesis and repression of transposons in the mouse male germline.

Q9UUE5	NUP85_SCHPO	Nucleoporin nup85	15226438	The fission yeast Nup107-120 complex functionally interacts with the small GTPase Ran/Spi1 and is required for mRNA export, nuclear pore distribution, and proper cell division.

Q9JM73	SRF_MOUSE	Serum response factor	15169892	Targeted inactivation of serum response factor in the developing heart results in myocardial defects and embryonic lethality.

Q8T6B9	PUF68_DROME	Poly(U)-binding-splicing factor half pint	11879639	Half pint regulates alternative splice site selection in Drosophila.

P42345	MTOR_HUMAN	Serine/threonine-protein kinase mTOR	12150926	Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action.

Q9NQ38	ISK5_HUMAN	Serine protease inhibitor Kazal-type 5	10419450	LEKTI, a novel 15-domain type of human serine proteinase inhibitor.

Q5EE38	ACD_MOUSE	Adrenocortical dysplasia protein	15537664	Urogenital and caudal dysgenesis in adrenocortical dysplasia (acd) mice is caused by a splicing mutation in a novel telomeric regulator.

O74333	NCE2_SCHPO	Non-classical export protein 2 homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9QYC3	BHA15_MOUSE	Class A basic helix-loop-helix protein 15	15665001	Aberrant localization of intracellular organelles, Ca2+ signaling, and exocytosis in Mist1 null mice.

Q06651	PIB1_YEAST	E3 ubiquitin-protein ligase PIB1	11526110	FYVE domain targets Pib1p ubiquitin ligase to endosome and vacuolar membranes.

P31016	DLG4_RAT	Disks large homolog 4	16495444	A novel family of adhesion-like molecules that interacts with the NMDA receptor.

Q30HU9	SPI1_CRAVI	Serine protease inhibitor Cvsi-1	16872855	A novel slow-tight binding serine protease inhibitor from eastern oyster (Crassostrea virginica) plasma inhibits perkinsin, the major extracellular protease of the oyster protozoan parasite Perkinsus marinus.

P32494	NGG1_YEAST	Chromatin-remodeling complexes subunit NGG1	12446794	The novel SLIK histone acetyltransferase complex functions in the yeast retrograde response pathway.

O15371	EIF3D_HUMAN	Eukaryotic translation initiation factor 3 subunit D	17581632	Reconstitution reveals the functional core of mammalian eIF3.

Q24592	JAK_DROME	Tyrosine-protein kinase hopscotch	8314084	Stripe-specific regulation of pair-rule genes by hopscotch, a putative Jak family tyrosine kinase in Drosophila.

Q9SPL2	CIP8_ARATH	E3 ubiquitin-protein ligase CIP8	10488108	The RING finger motif of photomorphogenic repressor COP1 specifically interacts with the RING-H2 motif of a novel Arabidopsis protein.

Q54C70	ODPA_DICDI	Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q5SUQ9	CTC1_MOUSE	CST complex subunit CTC1	19854130	RPA-like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathway.

P38827	SET1_YEAST	Histone-lysine N-methyltransferase, H3 lysine-4 specific	11687631	COMPASS: a complex of proteins associated with a trithorax-related SET domain protein.

Q9Y2R2	PTN22_HUMAN	Tyrosine-protein phosphatase non-receptor type 22	19167335	Large-scale structural analysis of the classical human protein tyrosine phosphatome.

P23693	TNNI3_RAT	Troponin I, cardiac muscle	15601779	Muscle-specific RING finger 1 is a bona fide ubiquitin ligase that degrades cardiac troponin I.

Q12133	SPC3_YEAST	Signal peptidase complex subunit SPC3	9148931	The yeast SPC22/23 homolog Spc3p is essential for signal peptidase activity.

P29506	UNC4_CAEEL	Homeobox protein unc-4	7904971	Dominant unc-37 mutations suppress the movement defect of a homeodomain mutation in unc-4, a neural specificity gene in Caenorhabditis elegans.

O14121	NDH1_SCHPO	Probable NADH-ubiquinone oxidoreductase C3A11.07, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q07800	PSR1_YEAST	Phosphatase PSR1	12090248	Yeast Whi2 and Psr1-phosphatase form a complex and regulate STRE- mediated gene expression.

O22194	AGP17_ARATH	Lysine-rich arabinogalactan protein 17	15840645	The lysine-rich arabinogalactan-protein subfamily in Arabidopsis: gene expression, glycoprotein purification and biochemical characterization.

Q9JK37	MYOZ1_MOUSE	Myozenin-1	11114196	Calsarcins, a novel family of sarcomeric calcineurin-binding proteins.

Q13470	TNK1_HUMAN	Non-receptor tyrosine-protein kinase TNK1	8632913	Tnk1: a novel intracellular tyrosine kinase gene isolated from human umbilical cord blood CD34+/Lin-/CD38- stem/progenitor cells.

Q9Y7K9	YGI7_SCHPO	PARP-type zinc finger-containing protein C2A9.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P58908	LECA_DIORO	Lectin alpha chain	18682294	Crystal structure of Dioclea rostrata lectin: insights into understanding the pH-dependent dimer-tetramer equilibrium and the structural basis for carbohydrate recognition in Diocleinae lectins.

P62280	RS11_HUMAN	40S ribosomal protein S11	3267208	Sequence of a cloned cDNA encoding human ribosomal protein S11.

Q7ZUS4	ST2S2_DANRE	Cytosolic sulfotransferase 2	12755695	Sulfation of hydroxychlorobiphenyls. Molecular cloning, expression, and functional characterization of zebrafish SULT1 sulfotransferases.

P53883	NOP13_YEAST	Nucleolar protein 13	11452019	Nucleolar protein Nop12p participates in synthesis of 25S rRNA in Saccharomyces cerevisiae.

Q95T64	PGPLA_DROME	Peptidoglycan-recognition protein LA	11106397	A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster.

Q04807	GLCM1_RAT	Glycosylation-dependent cell adhesion molecule 1	8100229	Cloning of a rat homologue of mouse GlyCAM 1 reveals conservation of structural domains.

Q6ZVT0	TTL10_HUMAN	Inactive polyglycylase TTLL10	19524510	Evolutionary divergence of enzymatic mechanisms for posttranslational polyglycylation.

Q9AVB0	LECB_PHYAM	Lectin-B	7772833	Purification and characterization of three mitogenic lectins from the roots of pokeweed (Phytolacca americana).

P62244	RS15A_HUMAN	40S ribosomal protein S15a	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

O60104	MED7_SCHPO	Mediator of RNA polymerase II transcription subunit 7	10625684	Purification and characterization of RNA polymerase II holoenzyme from Schizosaccharomyces pombe.

Q9NZC7	WWOX_HUMAN	WW domain-containing oxidoreductase	10786676	WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer.

P81786	ADH_MORSE	NAD-dependent alcohol dehydrogenase	9660191	Purification and characterization of an alcohol dehydrogenase from the Antarctic psychrophile Moraxella sp. TAE123.

Q02971	CADH7_ARATH	Cinnamyl alcohol dehydrogenase 7	17467016	Expression of cinnamyl alcohol dehydrogenases and their putative homologues during Arabidopsis thaliana growth and development: lessons for database annotations?

Q03410	SYCP1_RAT	Synaptonemal complex protein 1	1464329	A coiled-coil related protein specific for synapsed regions of meiotic prophase chromosomes.

Q66GS9	CP135_HUMAN	Centrosomal protein of 135 kDa	17681131	Plk4-induced centriole biogenesis in human cells.

P10868	GAMT_RAT	Guanidinoacetate N-methyltransferase	15533043	Catalytic mechanism of guanidinoacetate methyltransferase: crystal structures of guanidinoacetate methyltransferase ternary complexes.

O95707	RPP29_HUMAN	Ribonuclease P protein subunit p29	15096576	Mutual interactions between subunits of the human RNase MRP ribonucleoprotein complex.

Q9JMA2	TGT_MOUSE	Queuine tRNA-ribosyltransferase	19414587	Queuosine formation in eukaryotic tRNA occurs via a mitochondria- localized heteromeric transglycosylase.

P55795	HNRH2_HUMAN	Heterogeneous nuclear ribonucleoprotein H2	7499401	Heterogeneous nuclear ribonucleoproteins H, H', and F are members of a ubiquitously expressed subfamily of related but distinct proteins encoded by genes mapping to different chromosomes.

P59833	UGPI3_ARATH	Uncharacterized GPI-anchored protein At5g19250	12805588	Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis.

Q9VWY6	TAF8_DROME	Transcription initiation factor TFIID subunit 8	11134347	Prodos is a conserved transcriptional regulator that interacts with dTAF(II)16 in Drosophila melanogaster.

P32907	ATO2_YEAST	Ammonia transport outward protein 2	17395151	Association of putative ammonium exporters Ato with detergent- resistant compartments of plasma membrane during yeast colony development: pH affects Ato1p localisation in patches.

Q9UKJ1	PILRA_HUMAN	Paired immunoglobulin-like type 2 receptor alpha	10903717	FDF03, a novel inhibitory receptor of the immunoglobulin superfamily, is expressed by human dendritic and myeloid cells.

P37262	SOL2_YEAST	6-phosphogluconolactonase-like protein 2	14562095	Global analysis of protein localization in budding yeast.

P18510	IL1RA_HUMAN	Interleukin-1 receptor antagonist protein	7629520	Cloning and characterization of a new isoform of the interleukin 1 receptor antagonist.

Q9ESN3	TMM8A_MOUSE	Transmembrane protein 8A	11006113	Molecular cloning and chromosomal mapping of a novel five-span transmembrane protein gene, M83.

P36543	VATE1_HUMAN	V-type proton ATPase subunit E 1	8250920	Cloning and tissue distribution of subunits C, D, and E of the human vacuolar H(+)-ATPase.

P04637	P53_HUMAN	Cellular tumor antigen p53	8875926	Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2.

Q9C7S0	BZI60_ARATH	bZIP transcription factor 60	19017746	Arabidopsis bZIP60 is a proteolysis-activated transcription factor involved in the endoplasmic reticulum stress response.

P42695	CNDD3_HUMAN	Condensin-2 complex subunit D3	14532007	Differential contributions of condensin I and condensin II to mitotic chromosome architecture in vertebrate cells.

Q13126	MTAP_HUMAN	S-methyl-5'-thioadenosine phosphorylase	8687427	Purification and characterization of recombinant human 5'- methylthioadenosine phosphorylase: definite identification of coding cDNA.

Q3E7C1	TFB5_YEAST	RNA polymerase II transcription factor B subunit 5	14562095	Global analysis of protein localization in budding yeast.

O44516	EFN4_CAEEL	Ephrin-4	12403719	The divergent C. elegans ephrin EFN-4 functions in embryonic morphogenesis in a pathway independent of the VAB-1 Eph receptor.

P17661	DESM_HUMAN	Desmin	9736733	A dysfunctional desmin mutation in a patient with severe generalized myopathy.

Q8BGW3	BHE23_MOUSE	Class E basic helix-loop-helix protein 23	15363390	The transcription factor Bhlhb4 is required for rod bipolar cell maturation.

Q4U2R8	S22A6_HUMAN	Solute carrier family 22 member 6	9950961	Cloning of the human kidney PAH transporter: narrow substrate specificity and regulation by protein kinase C.

P53735	ZRG17_YEAST	Protein ZRG17	14562095	Global analysis of protein localization in budding yeast.

O60065	PEX14_SCHPO	Peroxisomal membrane protein pex14	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q60902	EP15R_MOUSE	Epidermal growth factor receptor substrate 15-like 1	9446614	Eps15R is a tyrosine kinase substrate with characteristics of a docking protein possibly involved in coated pits-mediated internalization.

P21283	VATC1_HUMAN	V-type proton ATPase subunit C 1	8250920	Cloning and tissue distribution of subunits C, D, and E of the human vacuolar H(+)-ATPase.

Q805F3	CATEA_XENLA	Cathepsin E-A	14561724	Differential expression of two cathepsin Es during metamorphosis- associated remodeling of the larval to adult type epithelium in Xenopus stomach.

Q92949	FOXJ1_HUMAN	Forkhead box protein J1	9073514	The human hepatocyte nuclear factor 3/fork head gene FKHL13: genomic structure and pattern of expression.

Q9NZV8	KCND2_HUMAN	Potassium voltage-gated channel subfamily D member 2	11287421	Conserved Kv4 N-terminal domain critical for effects of Kv channel- interacting protein 2.2 on channel expression and gating.

Q9LFF1	PP281_ARATH	Pentatricopeptide repeat-containing protein At3g53700, chloroplastic	15634699	Genetic and molecular identification of genes required for female gametophyte development and function in Arabidopsis.

O75791	GRAP2_HUMAN	GRB2-related adapter protein 2	12359715	Molecular cloning of a novel gene encoding a membrane-associated adaptor protein (LAX) in lymphocyte signaling.

Q9ERI2	RB27A_MOUSE	Ras-related protein Rab-27A	11887186	Identification of an organelle receptor for myosin-Va.

Q9R0U0	SRS10_MOUSE	Serine/arginine-rich splicing factor 10	9774382	Oncoprotein TLS interacts with serine-arginine proteins involved in RNA splicing.

A1ZAU8	SSP4_DROME	Short spindle protein 4	17412918	Genes required for mitotic spindle assembly in Drosophila S2 cells.

P53163	MNP1_YEAST	54S ribosomal protein L12, mitochondrial	15221522	A 22 kDa protein specific for yeast mitochondrial nucleoids is an unidentified putative ribosomal protein encoded in open reading frame YGL068W.

Q9R1M7	NMD3A_RAT	Glutamate [NMDA] receptor subunit 3A	9891978	Identification of a long variant of mRNA encoding the NR3 subunit of the NMDA receptor: its regional distribution and developmental expression in the rat brain.

Q9UM01	YLAT1_HUMAN	Y+L amino acid transporter 1	9829974	Identification and characterization of a membrane protein (y+L amino acid transporter-1) that associates with 4F2hc to encode the amino acid transport activity y+L. A candidate gene for lysinuric protein intolerance.

Q55169	RCP1_SYNY3	Response regulator rcp1	9278513	A cyanobacterial phytochrome two-component light sensory system.

Q8WWY7	WFD12_HUMAN	WAP four-disulfide core domain protein 12	11779191	Identification of a novel protease inhibitor gene that is highly expressed in the prostate.

Q6QGW5	SRA1_RAT	Steroid receptor RNA activator 1	12350225	A novel steroid receptor co-activator protein (SRAP) as an alternative form of steroid receptor RNA-activator gene: expression in prostate cancer cells and enhancement of androgen receptor activity.

P39007	STT3_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3	9405463	The highly conserved Stt3 protein is a subunit of the yeast oligosaccharyltransferase and forms a subcomplex with Ost3p and Ost4p.

P54697	MYOJ_DICDI	Myosin-J heavy chain	18650439	Dictyostelium myosin-5b is a conditional processive motor.

Q8K1M4	GLIS1_MOUSE	Zinc finger protein GLIS1	12385751	A novel gene, GliH1, with homology to the Gli zinc finger domain not required for mouse development.

Q9HAT8	PELI2_HUMAN	Protein pellino homolog 2	12860405	Characterization of Pellino2, a substrate of IRAK1 and IRAK4.

Q9SNC3	FLA4_ARATH	Fasciclin-like arabinogalactan protein 4	12509519	The Arabidopsis SOS5 locus encodes a putative cell surface adhesion protein and is required for normal cell expansion.

Q92620	PRP16_HUMAN	Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16	9524131	Human homologs of yeast prp16 and prp17 reveal conservation of the mechanism for catalytic step II of pre-mRNA splicing.

Q9LK35	THE1_ARATH	Receptor-like protein kinase THESEUS 1	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

P33279	E2AK1_RABIT	Eukaryotic translation initiation factor 2-alpha kinase 1	3745199	The NH2-terminal sequence of the alpha and gamma subunits of eukaryotic initiation factor 2 and the phosphorylation site for the heme-regulated eIF-2 alpha kinase.

O73689	ZIC1_XENLA	Zinc finger protein ZIC 1	16871635	The Xfeb gene is directly upregulated by Zic1 during early neural development.

P06703	S10A6_HUMAN	Protein S100-A6	19724273	S100A6 binds to annexin 2 in pancreatic cancer cells and promotes pancreatic cancer cell motility.

P81644	APOA2_BOVIN	Apolipoprotein A-II	9538260	Purification, primary structure, and antimicrobial activities of bovine apolipoprotein A-II.

Q8RY17	WAKLI_ARATH	Wall-associated receptor kinase-like 22	15965251	RESISTANCE TO FUSARIUM OXYSPORUM 1, a dominant Arabidopsis disease- resistance gene, is not race specific.

Q9H2J4	PDCL3_HUMAN	Phosducin-like protein 3	15371430	VIAF, a conserved inhibitor of apoptosis (IAP)-interacting factor that modulates caspase activation.

O60469	DSCAM_HUMAN	Down syndrome cell adhesion molecule	9426258	DSCAM: a novel member of the immunoglobulin superfamily maps in a Down syndrome region and is involved in the development of the nervous system.

P50395	GDIB_HUMAN	Rab GDP dissociation inhibitor beta	11809807	The hematopoiesis-specific GTP-binding protein RhoH is GTPase deficient and modulates activities of other Rho GTPases by an inhibitory function.

P38283	SLI15_YEAST	Inner centromere protein-related protein SLI15	10385519	Sli15 associates with the ipl1 protein kinase to promote proper chromosome segregation in Saccharomyces cerevisiae.

Q02973	EM6_ARATH	Em-like protein GEA6	8492809	Two different Em-like genes are expressed in Arabidopsis thaliana seeds during maturation.

Q12286	SUT2_YEAST	Sterol uptake protein 2	15030478	SUT2 is a novel multicopy suppressor of low activity of the cAMP/protein kinase A pathway in yeast.

O43525	KCNQ3_HUMAN	Potassium voltage-gated channel subfamily KQT member 3	9677360	Functional expression of two KvLQT1-related potassium channels responsible for an inherited idiopathic epilepsy.

Q9VNG0	MED27_DROME	Mediator of RNA polymerase II transcription subunit 27	12021283	Novel Mediator proteins of the small Mediator complex in Drosophila SL2 cells.

P34232	MTR2_YEAST	mRNA transport regulator MTR2	7865887	Nuclear mRNA accumulation causes nucleolar fragmentation in yeast mtr2 mutant.

Q03591	FHR1_HUMAN	Complement factor H-related protein 1	1711047	Molecular cloning of a human serum protein structurally related to complement factor H.

Q9VTE9	ULA1_DROME	NEDD8-activating enzyme E1 regulatory subunit	16628230	Drosophila homolog of APP-BP1 (dAPP-BP1) interacts antagonistically with APPL during Drosophila development.

Q05584	GLO2_YEAST	Hydroxyacylglutathione hydrolase, cytoplasmic isozyme	9261170	Identification and phenotypic analysis of two glyoxalase II encoding genes from Saccharomyces cerevisiae, GLO2 and GLO4, and intracellular localization of the corresponding proteins.

P06753	TPM3_HUMAN	Tropomyosin alpha-3 chain	3018581	Tissue-specific expression of the human tropomyosin gene involved in the generation of the trk oncogene.

O65258	BAM2_ARATH	Beta-amylase 2, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q8R015	MUTED_MOUSE	Protein Muted	12923531	Hermansky-Pudlak syndrome type 7 (HPS-7) results from mutant dysbindin, a member of the biogenesis of lysosome-related organelles complex 1 (BLOC-1).

P49736	MCM2_HUMAN	DNA replication licensing factor MCM2	16387653	ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.

Q9VCU9	DCR1_DROME	Endoribonuclease Dcr-1	11201747	Role for a bidentate ribonuclease in the initiation step of RNA interference.

Q9GYH7	RME6_CAEEL	Receptor-mediated endocytosis protein 6	15895077	Caenorhabditis elegans RME-6 is a novel regulator of RAB-5 at the clathrin-coated pit.

P07560	SEC4_YEAST	Ras-related protein SEC4	11943201	Identification of the novel proteins Yip4p and Yip5p as Rab GTPase interacting factors.

O13853	ITS3_SCHPO	Phosphatidylinositol-4-phosphate 5-kinase its3	9873063	Regulation of phosphatidylinositol 4-phosphate 5-kinase from Schizosaccharomyces pombe by casein kinase I.

Q8VCG9	RFXAP_MOUSE	Regulatory factor X-associated protein	11486010	Expression of the three human major histocompatibility complex class II isotypes exhibits a differential dependence on the transcription factor RFXAP.

Q9Z0X4	PDE3A_MOUSE	cGMP-inhibited 3',5'-cyclic phosphodiesterase A	11420239	Cloning and characterization of the cyclic guanosine monophosphate- inhibited phosphodiesterase PDE3A expressed in mouse oocyte.

Q9FKD6	SINL8_ARATH	E3 ubiquitin-protein ligase SINA-like 8	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q9SY69	PPR29_ARATH	Pentatricopeptide repeat-containing protein At1g10270	16489121	Arabidopsis GLUTAMINE-RICH PROTEIN23 is essential for early embryogenesis and encodes a novel nuclear PPR motif protein that interacts with RNA polymerase II subunit III.

Q9P7D8	YOFA_SCHPO	Uncharacterized rhomboid protein P4H10.10, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O75828	CBR3_HUMAN	Carbonyl reductase [NADPH] 3	18493841	Different functions between human monomeric carbonyl reductase 3 and carbonyl reductase 1.

P53136	NSA1_YEAST	Ribosome biogenesis protein NSA1	17443350	In vivo functional characterization of the Saccharomyces cerevisiae 60S biogenesis GTPase Nog1.

Q02910	CPN_DROME	Calphotin	8094559	Calphotin: a Drosophila photoreceptor cell calcium-binding protein.

Q00776	AP1M1_YEAST	AP-1 complex subunit mu-1-I	10564262	Adaptor complex-independent clathrin function in yeast.

P12644	BMP4_HUMAN	Bone morphogenetic protein 4	3201241	Novel regulators of bone formation: molecular clones and activities.

P40794	BNK_DROME	Protein bottleneck	8402919	Bottleneck acts as a regulator of the microfilament network governing cellularization of the Drosophila embryo.

Q9CQJ4	RING2_MOUSE	E3 ubiquitin-protein ligase RING2	12183370	Involvement of the Polycomb-group gene Ring1B in the specification of the anterior-posterior axis in mice.

O34939	YDIO_BACSU	Probable BsuMI modification methylase subunit ydiO	11751814	Molecular organization of intrinsic restriction and modification genes BsuM of Bacillus subtilis Marburg.

P43132	BRE2_YEAST	COMPASS component BRE2	11687631	COMPASS: a complex of proteins associated with a trithorax-related SET domain protein.

P36116	VPS51_YEAST	Vacuolar protein sorting-associated protein 51	12446664	Vps51 is part of the yeast Vps fifty-three tethering complex essential for retrograde traffic from the early endosome and Cvt vesicle completion.

Q63961	EGLN_MOUSE	Endoglin	8194490	Molecular characterization and in situ localization of murine endoglin reveal that it is a transforming growth factor-beta binding protein of endothelial and stromal cells.

Q07292	KRAF1_CAEEL	Raf homolog serine/threonine-protein kinase	11861555	Caenorhabditis elegans lin-45 raf is essential for larval viability, fertility and the induction of vulval cell fates.

Q9HBU6	EKI1_HUMAN	Ethanolamine kinase 1	11044454	Overexpression of a mammalian ethanolamine-specific kinase accelerates the CDP-ethanolamine pathway.

P97924	KALRN_RAT	Kalirin	10777487	Isoforms of kalirin, a neuronal Dbl family member, generated through use of different 5'- and 3'-ends along with an internal translational initiation site.

Q8BX46	SKOR1_MOUSE	SKI family transcriptional corepressor 1	15528197	Corl1, a novel neuronal lineage-specific transcriptional corepressor for the homeodomain transcription factor Lbx1.

Q64605	PTPRS_RAT	Receptor-type tyrosine-protein phosphatase S	8068021	Molecular cloning and expression of a unique receptor-like protein- tyrosine-phosphatase in the leucocyte-common-antigen-related phosphate family.

A6JFQ6	CLVS1_RAT	Clavesin-1	19651769	The clavesin family: neuron-specific lipid- and clathrin-binding Sec14 proteins regulating lysosomal morphology.

P22265	TSH_DROME	Protein teashirt	15110046	Dorso-ventral asymmetric functions of teashirt in Drosophila eye development depend on spatial cues provided by early DV patterning genes.

O95429	BAG4_HUMAN	BAG family molecular chaperone regulator 4	9915703	Prevention of constitutive TNF receptor 1 signaling by silencer of death domains.

Q02972	CADH8_ARATH	Cinnamyl alcohol dehydrogenase 8	14745009	Functional reclassification of the putative cinnamyl alcohol dehydrogenase multigene family in Arabidopsis.

Q2V3H2	PUP7_ARATH	Probable purine permease 7	10662864	A new family of high-affinity transporters for adenine, cytosine, and purine derivatives in Arabidopsis.

P08887	IL6RA_HUMAN	Interleukin-6 receptor subunit alpha	12829785	Hexameric structure and assembly of the interleukin-6/IL-6 alpha- receptor/gp130 complex.

Q0WSH6	PP312_ARATH	Pentatricopeptide repeat-containing protein At4g14850	17213228	LOVASTATIN INSENSITIVE 1, a novel pentatricopeptide repeat protein, is a potential regulatory factor of isoprenoid biosynthesis in Arabidopsis.

Q9NX08	COMD8_HUMAN	COMM domain-containing protein 8	15799966	COMMD proteins, a novel family of structural and functional homologs of MURR1.

Q07551	KAR_YEAST	NADPH-dependent alpha-keto amide reductase	11306085	Functional genomic studies of aldo-keto reductases.

Q03799	RT08_YEAST	37S ribosomal protein S8, mitochondrial	12392552	Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components.

P80210	PURA_YEAST	Adenylosuccinate synthetase	8706758	Enzymatic properties and inhibition by single-stranded autonomously replicating sequences of adenylosuccinate synthase from Saccharomyces cerevisiae.

O14498	ISLR_HUMAN	Immunoglobulin superfamily containing leucine-rich repeat protein	9325048	Cloning of the cDNA for a new member of the immunoglobulin superfamily (ISLR) containing leucine-rich repeat (LRR).

Q12143	NSL1_YEAST	Kinetochore-associated protein NSL1	14657030	Nsl1p is essential for the establishment of bipolarity and the localization of the Dam-Duo complex.

P28033	CEBPB_MOUSE	CCAAT/enhancer-binding protein beta	15644333	Delta-interacting protein A, a new inhibitory partner of CCAAT/enhancer-binding protein beta, implicated in adipocyte differentiation.

Q80WA4	NOVA1_RAT	RNA-binding protein Nova-1	12124753	Role of Nova-1 in regulating alpha2N, a novel glycine receptor splice variant, in developing spinal cord neurons.

Q10423	CCE1_SCHPO	Cruciform cutting endonuclease 1, mitochondrial	10954073	The Holliday junction resolvase SpCCE1 prevents mitochondrial DNA aggregation in Schizosaccharomyces pombe.

P38992	SUR2_YEAST	Sphingolipid C4-hydroxylase SUR2	9556590	Syringomycin action gene SYR2 is essential for sphingolipid 4- hydroxylation in Saccharomyces cerevisiae.

Q5RLM2	S22A7_RAT	Solute carrier family 22 member 7	9650585	Identification of multispecific organic anion transporter 2 expressed predominantly in the liver.

O94265	THI21_SCHPO	Putative hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O59757	SPC7_SCHPO	Kinetochore protein spc7	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9FUY2	LEUNG_ARATH	Transcriptional corepressor LEUNIG	15277686	Transcriptional repression of target genes by LEUNIG and SEUSS, two interacting regulatory proteins for Arabidopsis flower development.

O22265	SR43C_ARATH	Signal recognition particle 43 kDa protein, chloroplastic	9878634	A chromodomain protein encoded by the arabidopsis CAO gene is a plant-specific component of the chloroplast signal recognition particle pathway that is involved in LHCP targeting.

Q9ZNV8	AHP2_ARATH	Histidine-containing phosphotransfer protein 2	11158442	Two types of putative nuclear factors that physically interact with histidine-containing phosphotransfer (Hpt) domains, signaling mediators in His-to-Asp phosphorelay, in Arabidopsis thaliana.

Q6ZMQ8	LMTK1_HUMAN	Serine/threonine-protein kinase LMTK1	14521924	Apoptosis-associated tyrosine kinase is a Cdk5 activator p35 binding protein.

P14680	YAK1_YEAST	Dual specificity protein kinase YAK1	11358866	Yak1p, a DYRK family kinase, translocates to the nucleus and phosphorylates yeast Pop2p in response to a glucose signal.

Q12052	TGS1_YEAST	Trimethylguanosine synthase	11983179	Hypermethylation of the cap structure of both yeast snRNAs and snoRNAs requires a conserved methyltransferase that is localized to the nucleolus.

P36626	REC8_SCHPO	Meiotic recombination protein rec8	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O14324	YB79_SCHPO	Uncharacterized membrane protein C16E9.09c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8QGU6	LEDGE_XENLA	Protein ledgerline	16971787	Ledgerline, a novel Xenopus laevis gene, regulates differentiation of presomitic mesoderm during somitogenesis.

Q24434	ORD_DROME	Protein ORD	8635478	Identification of ORD, a Drosophila protein essential for sister chromatid cohesion.

P34111	TFC3_YEAST	Transcription factor tau 138 kDa subunit	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P53350	PLK1_HUMAN	Serine/threonine-protein kinase PLK1	17617734	Shugoshin 1 plays a central role in kinetochore assembly and is required for kinetochore targeting of Plk1.

O09113	OTP_MOUSE	Homeobox protein orthopedia	10557207	Progressive impairment of developing neuroendocrine cell lineages in the hypothalamus of mice lacking the Orthopedia gene.

O70156	OLR1_RAT	Oxidized low-density lipoprotein receptor 1	12538855	Lectin-like oxidized LDL receptor-1 is a cell-adhesion molecule involved in endotoxin-induced inflammation.

Q9H1X1	RSPH9_HUMAN	Radial spoke head protein 9 homolog	19200523	Mutations in radial spoke head protein genes RSPH9 and RSPH4A cause primary ciliary dyskinesia with central-microtubular-pair abnormalities.

Q8WT57	FAR1_ONCOC	Fatty-acid and retinol-binding protein 1	12106870	The FAR proteins of filarial nematodes: secretion, glycosylation and lipid binding characteristics.

P05230	FGF1_HUMAN	Heparin-binding growth factor 1	14732692	Insights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuity.

Q9Z339	GSTO1_RAT	Glutathione S-transferase omega-1	9786866	Molecular cloning and functional expression of rat liver glutathione- dependent dehydroascorbate reductase.

Q71DJ5	LIP1_ARATH	Triacylglycerol lipase 1	16226259	Identification and characterization of a triacylglycerol lipase in Arabidopsis homologous to mammalian acid lipases.

Q12887	COX10_HUMAN	Protoheme IX farnesyltransferase, mitochondrial	12928484	Mutations in COX10 result in a defect in mitochondrial heme A biosynthesis and account for multiple, early-onset clinical phenotypes associated with isolated COX deficiency.

Q9EQC5	NTKL_MOUSE	N-terminal kinase-like protein	12783284	Cloning and characterization of a novel gene which encodes a protein interacting with the mitosis-associated kinase-like protein NTKL.

Q7Z991	YE31_SCHPO	Uncharacterized ABC transporter ATP-binding protein C20G4.01	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9S7T8	SPZX_ARATH	Serpin-ZX	17028019	Serpin1 of Arabidopsis thaliana is a suicide inhibitor for metacaspase 9.

O14273	YET4_SCHPO	Meiotically up-regulated protein C8C9.04	12161753	The transcriptional program of meiosis and sporulation in fission yeast.

P40161	RT106_YEAST	Histone chaperone RTT106	16157874	Rtt106p is a histone chaperone involved in heterochromatin-mediated silencing.

Q9UHI6	DDX20_HUMAN	Probable ATP-dependent RNA helicase DDX20	10601333	Gemin3: a novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and a component of gems.

Q12287	COX17_YEAST	Cytochrome c oxidase copper chaperone	8662933	Characterization of COX17, a yeast gene involved in copper metabolism and assembly of cytochrome oxidase.

O94524	GTO2_SCHPO	Glutathione S-transferase omega-like 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9GZV4	IF5A2_HUMAN	Eukaryotic translation initiation factor 5A-2	14622290	Identification and characterization of eukaryotic initiation factor 5A-2.

Q13268	DHRS2_HUMAN	Dehydrogenase/reductase SDR family member 2	11997086	A human short-chain dehydrogenase/reductase gene: structure, chromosomal localization, tissue expression and subcellular localization of its product.

Q9NS56	TOPRS_HUMAN	E3 ubiquitin-protein ligase Topors	19473992	Plk1-mediated phosphorylation of Topors regulates p53 stability.

Q12074	SPEE_YEAST	Spermidine synthase	9073064	Spermidine biosynthesis in Saccharomyces cerevisae: polyamine requirement of a null mutant of the SPE3 gene (spermidine synthase).

Q9C5T4	WRK18_ARATH	WRKY transcription factor 18	12068113	Potentiation of developmentally regulated plant defense response by AtWRKY18, a pathogen-induced Arabidopsis transcription factor.

Q9N337	MED6_CAEEL	Mediator of RNA polymerase II transcription subunit 6	11728440	The MED-7 transcriptional mediator encoded by let-49 is required for gonad and germ cell development in Caenorhabditis elegans.

Q62755	NR1H2_RAT	Oxysterols receptor LXR-beta	7971966	Ubiquitous receptor: a receptor that modulates gene activation by retinoic acid and thyroid hormone receptors.

Q8TAP6	CEP76_HUMAN	Centrosomal protein of 76 kDa	19460342	Cep76, a centrosomal protein that specifically restrains centriole reduplication.

Q869Q3	NAPA_DICDI	Nck-associated protein 1 homolog	16581519	Nap1 regulates Dictyostelium cell motility and adhesion through SCAR- dependent and -independent pathways.

Q7TNJ4	AMGO2_RAT	Amphoterin-induced protein 2	12629050	AMIGO, a transmembrane protein implicated in axon tract development, defines a novel protein family with leucine-rich repeats.

P12074	CX6A1_HUMAN	Cytochrome c oxidase subunit 6A1, mitochondrial	2549515	Sequence of a cDNA specifying subunit VIa of human cytochrome c oxidase.

Q14126	DSG2_HUMAN	Desmoglein-2	8143788	Identification of the ubiquitous human desmoglein, Dsg2, and the expression catalogue of the desmoglein subfamily of desmosomal cadherins.

Q9H0W8	SMG9_HUMAN	Protein SMG9	19417104	SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay.

O88951	LIN7B_MOUSE	Protein lin-7 homolog B	10341223	Characterization of MALS/Velis-1, -2, and -3: a family of mammalian LIN-7 homologs enriched at brain synapses in association with the postsynaptic density-95/NMDA receptor postsynaptic complex.

Q7TNB8	SBNO2_MOUSE	Protein strawberry notch homolog 2	18025162	A transcriptional repressor and corepressor induced by the STAT3- regulated anti-inflammatory signaling pathway.

Q00537	CDK17_HUMAN	Cell division protein kinase 17	1639063	A family of human cdc2-related protein kinases.

Q9Y7X7	YGRB_SCHPO	GRIP and coiled-coil domain-containing protein C365.11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q96Q11	TRNT1_HUMAN	tRNA-nucleotidyltransferase 1, mitochondrial	11504732	Identification and characterization of mammalian mitochondrial tRNA nucleotidyltransferases.

Q9WU78	PDC6I_MOUSE	Programmed cell death 6-interacting protein	9880530	Cloning of AIP1, a novel protein that associates with the apoptosis- linked gene ALG-2 in a Ca2+-dependent reaction.

P84795	CEKI_CAEEC	Proteinase inhibitor CeKI	15576329	A proteinase inhibitor from Caesalpinia echinata (pau-brasil) seeds for plasma kallikrein, plasmin and factor XIIa.

O42606	NGN1_DANRE	Neurogenin-1	16549779	Neurogenin1 is a determinant of zebrafish basal forebrain dopaminergic neurons and is regulated by the conserved zinc finger protein Tof/Fezl.

Q8LCT3	TRL22_ARATH	Thioredoxin-like 2-2, chloroplastic	19109414	A small family of chloroplast atypical thioredoxins.

Q8R416	PKR1_RAT	Prokineticin receptor 1	12054613	Isolation and identification of EG-VEGF/prokineticins as cognate ligands for two orphan G-protein-coupled receptors.

Q9LQU4	Y1487_ARATH	Uncharacterized protein At1g14870	16618929	Mapping the Arabidopsis organelle proteome.

Q40987	LECR_PEA	Nodule lectin	8685275	Identification of a new pea gene, PsNlec1, encoding a lectin-like glycoprotein isolated from the symbiosomes of root nodules.

Q98SR9	TWS1B_DANRE	Twisted gastrulation protein homolog 1-B	15604098	Twisted gastrulation enhances BMP signaling through chordin dependent and independent mechanisms.

P06607	VIT3_DROME	Vitellogenin-3	1909425	Characterization, molecular cloning and sequencing of YP3s1, a fertile yolk protein 3 mutant in Drosophila.

Q44335	FLGB_AGRT5	Flagellar basal-body rod protein flgB	9161424	Isolation and characterisation of a linked cluster of genes from Agrobacterium tumefaciens encoding proteins involved in flagellar basal-body structure.

Q920H1	SG3A2_MOUSE	Secretoglobin family 3A member 2	11682631	UGRP1, a uteroglobin/Clara cell secretory protein-related protein, is a novel lung-enriched downstream target gene for the T/EBP/NKX2.1 homeodomain transcription factor.

Q9ZVJ6	ANXD4_ARATH	Annexin D4	16531057	Expression profiling of the Arabidopsis annexin gene family during germination, de-etiolation and abiotic stress.

Q12494	KCS1_YEAST	Inositol hexakisphosphate kinase 1	14562095	Global analysis of protein localization in budding yeast.

O95757	HS74L_HUMAN	Heat shock 70 kDa protein 4L	10524232	Cloning of human cDNAs for Apg-1 and Apg-2, members of the Hsp110 family, and chromosomal assignment of their genes.

P87060	POP1_SCHPO	WD repeat-containing protein pop1	14970237	Requirement of the SCFPop1/Pop2 ubiquitin ligase for degradation of the fission yeast S phase cyclin Cig2.

Q9DC77	SMPX_MOUSE	Small muscular protein	11401441	Identification of a novel stretch-responsive skeletal muscle gene (Smpx).

P36412	RB11A_DICDI	Ras-related protein Rab-11A	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q9S7H8	ICS1_ARATH	Isochorismate synthase 1, chloroplastic	18451262	Characterization and biological function of the ISOCHORISMATE SYNTHASE2 gene of Arabidopsis.

Q9JM71	K1B27_MOUSE	Kallikrein 1-related peptidase b27	11082197	Cloning and characterization of mouse Klk27, a novel tissue kallikrein expressed in testicular Leydig cells and exhibiting chymotrypsin-like specificity.

Q24185	HOOK_DROME	Protein hook	11238449	The Golgi-associated hook3 protein is a member of a novel family of microtubule-binding proteins.

P84266	DAH43_LITDA	Dahlein-4.3	11555873	Bioactive dahlein peptides from the skin secretions of the Australian aquatic frog Litoria dahlii: sequence determination by electrospray mass spectrometry.

P28566	5HT1E_HUMAN	5-hydroxytryptamine receptor 1E	1608964	Molecular cloning of a serotonin receptor from human brain (5HT1E): a fifth 5HT1-like subtype.

O42893	TREA_SCHPO	Neutral trehalase	9838130	Analysis of the ntp1+ gene, encoding neutral trehalase in the fission yeast Schizosaccharomyces pombe.

Q12052	TGS1_YEAST	Trimethylguanosine synthase	15340060	The small nucle(ol)ar RNA cap trimethyltransferase is required for ribosome synthesis and intact nucleolar morphology.

P36124	SET3_YEAST	SET domain-containing protein 3	11711434	The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program.

P00403	COX2_HUMAN	Cytochrome c oxidase subunit 2	2550900	Nucleotide sequence of human mitochondrial cytochrome c oxidase II cDNA.

P37302	APE3_YEAST	Aminopeptidase Y	8175799	Aminopeptidase Y, a new aminopeptidase from Saccharomyces cerevisiae. Purification, properties, localization, and processing by protease B.

O64763	ATL9_ARATH	E3 ubiquitin-protein ligase ATL9	15644464	Functional analysis of the RING-type ubiquitin ligase family of Arabidopsis.

Q6UPE1	ETFD_RAT	Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial	16248429	cDNA cloning, functional expression and cellular localization of rat liver mitochondrial electron-transfer flavoprotein-ubiquinone oxidoreductase protein.

Q9MZF4	DUOX1_CANFA	Dual oxidase 1	10806195	Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family.

Q9VCZ3	OCTB1_DROME	Octopamine receptor beta-1R	15816867	A family of octopamine receptors that specifically induce cyclic AMP production or Ca2+ release in Drosophila melanogaster.

Q9USI4	SAC32_SCHPO	SAC3 family protein 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q7Z4N2	TRPM1_HUMAN	Transient receptor potential cation channel subfamily M member 1	19878917	Recessive mutations of the gene TRPM1 abrogate ON bipolar cell function and cause complete congenital stationary night blindness in humans.

Q811Q0	KCMB2_RAT	Calcium-activated potassium channel subunit beta-2	12454985	Expression of a Ca2+-activated BK channel mRNA and its splice variants in the rat cochlea.

Q54JA4	SIBD_DICDI	Integrin beta-like protein D	16699495	An adhesion molecule in free-living Dictyostelium amoebae with integrin beta features.

Q9VMA3	CUP_DROME	Protein cup	11060247	Nanos interacts with cup in the female germline of Drosophila.

P28300	LYOX_HUMAN	Protein-lysine 6-oxidase	1352776	Characterization of the human lysyl oxidase gene locus.

P90916	LIN53_CAEEL	Probable histone-binding protein lin-53	9875852	lin-35 and lin-53, two genes that antagonize a C. elegans Ras pathway, encode proteins similar to Rb and its binding protein RbAp48.

Q12239	YO107_YEAST	Uncharacterized membrane protein YOL107W	14562095	Global analysis of protein localization in budding yeast.

P97924	KALRN_RAT	Kalirin	8910496	Novel proteins that interact with the COOH-terminal cytosolic routing determinants of an integral membrane peptide-processing enzyme.

O43525	KCNQ3_HUMAN	Potassium voltage-gated channel subfamily KQT member 3	9425900	A pore mutation in a novel KQT-like potassium channel gene in an idiopathic epilepsy family.

O75063	XYLK_HUMAN	Glycosaminoglycan xylosylkinase	19473117	FAM20B is a kinase that phosphorylates xylose in the glycosaminoglycan-protein linkage region.

P90901	IFA1_CAEEL	Intermediate filament protein ifa-1	15540462	Most genes encoding cytoplasmic intermediate filament (IF) proteins of the nematode Caenorhabditis elegans are required in late embryogenesis.

Q12866	MERTK_HUMAN	Tyrosine-protein kinase Mer	8086340	Cloning and mRNA expression analysis of a novel human protooncogene, c-mer.

P49917	DNLI4_HUMAN	DNA ligase 4	17396150	A novel human AP endonuclease with conserved zinc-finger-like motifs involved in DNA strand break responses.

P41250	SYG_HUMAN	Glycyl-tRNA synthetase	19710017	Crystal structures and biochemical analyses suggest a unique mechanism and role for human glycyl-tRNA synthetase in Ap4A homeostasis.

Q9D6J1	LASS4_MOUSE	LAG1 longevity assurance homolog 4	15823095	Mammalian Lass6 and its related family members regulate synthesis of specific ceramides.

P56730	NETR_HUMAN	Neurotrypsin	9540828	Cloning and sequencing of the cDNA encoding human neurotrypsin.

Q7TQC5	APTX_MOUSE	Aprataxin	11586300	The gene mutated in ataxia-ocular apraxia 1 encodes the new HIT/Zn- finger protein aprataxin.

Q9UTR5	RGF2_SCHPO	Rho1 guanine nucleotide exchange factor 2	16324155	Rho1-GEFs Rgf1 and Rgf2 are involved in formation of cell wall and septum, while Rgf3 is involved in cytokinesis in fission yeast.

Q9C106	RPC3_SCHPO	DNA-directed RNA polymerase III subunit rpc3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9P289	MST4_HUMAN	Serine/threonine-protein kinase MST4	11641781	MST4, a new Ste20-related kinase that mediates cell growth and transformation via modulating ERK pathway.

Q9JKT4	TR105_MOUSE	Taste receptor type 2 member 105	15759003	The receptors and coding logic for bitter taste.

P07713	DECA_DROME	Protein decapentaplegic	9636086	TGF-beta/BMP superfamily members, Gbb-60A and Dpp, cooperate to provide pattern information and establish cell identity in the Drosophila wing.

Q7Z9I1	YQ39_SCHPO	Putative cell agglutination protein C188.09c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O74394	RM39_SCHPO	60S ribosomal protein L39, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9HDV3	YOE7_SCHPO	UPF0663 protein P19A11.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9WU56	TRUA_MOUSE	tRNA pseudouridine synthase A, mitochondrial	11085940	Mouse pseudouridine synthase 1: gene structure and alternative splicing of pre-mRNA.

P00918	CAH2_HUMAN	Carbonic anhydrase 2	3151020	Crystallographic studies of inhibitor binding sites in human carbonic anhydrase II: a pentacoordinated binding of the SCN-ion to the zinc at high pH.

P16989	DBPA_HUMAN	DNA-binding protein A	2977358	Two human genes isolated by a novel method encode DNA-binding proteins containing a common region of homology.

P46984	GON7_YEAST	Protein GON7	16564010	A genome-wide screen identifies the evolutionarily conserved KEOPS complex as a telomere regulator.

Q14520	HABP2_HUMAN	Hyaluronan-binding protein 2	8827452	Purification and characterization of a novel hyaluronan-binding protein (PHBP) from human plasma: it has three EGF, a kringle and a serine protease domain, similar to hepatocyte growth factor activator.

Q14203	DCTN1_HUMAN	Dynactin subunit 1	17532294	FBXL5 interacts with p150Glued and regulates its ubiquitination.

P22057	PTGDS_RAT	Prostaglandin-H2 D-isomerase	10387044	Binding of biliverdin, bilirubin, and thyroid hormones to lipocalin- type prostaglandin D synthase.

P68106	FKB1B_HUMAN	Peptidyl-prolyl cis-trans isomerase FKBP1B	7592869	A novel FK506 binding protein can mediate the immunosuppressive effects of FK506 and is associated with the cardiac ryanodine receptor.

Q53HV7	SMUG1_HUMAN	Single-strand selective monofunctional uracil DNA glycosylase	11526119	Definitive identification of mammalian 5-hydroxymethyluracil DNA N- glycosylase activity as SMUG1.

Q9BQ83	SLX1_HUMAN	Structure-specific endonuclease subunit SLX1	19596235	Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair.

Q9ERI5	JMJD6_MOUSE	Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6	14729065	Nuclear localization of the phosphatidylserine receptor protein via multiple nuclear localization signals.

P25618	CWH43_YEAST	Protein CWH43	17714445	CWH43 is required for the introduction of ceramides into GPI anchors in Saccharomyces cerevisiae.

Q9Y7Q1	YQ68_SCHPO	Uncharacterized ORAOV1 family protein C191.08	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P40380	RUM1_SCHPO	Cyclin-dependent kinase inhibitor rum1	9614176	Cyclin B proteolysis and the cyclin-dependent kinase inhibitor rum1p are required for pheromone-induced G1 arrest in fission yeast.

Q92316	OST5_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST5	16297388	Yeast oligosaccharyltransferase consists of two functionally distinct sub-complexes, specified by either the Ost3p or Ost6p subunit.

Q03935	YAP6_YEAST	AP-1-like transcription factor YAP6	11179441	Two nuclear proteins, Cin5 and Ydr259c, confer resistance to cisplatin in Saccharomyces cerevisiae.

Q9FQ03	XRN3_ARATH	5'-3' exoribonuclease 3	17993620	Arabidopsis FIERY1, XRN2, and XRN3 are endogenous RNA silencing suppressors.

Q9P6Q0	YKCA_SCHPO	Uncharacterized protein C644.10	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P46897	ATHB7_ARATH	Homeobox-leucine zipper protein ATHB-7	8771791	The Arabidopsis homeobox gene ATHB-7 is induced by water deficit and by abscisic acid.

P81909	OR22A_DROME	Odorant receptor 22a	10089887	A spatial map of olfactory receptor expression in the Drosophila antenna.

P23833	SCO1_YEAST	Protein SCO1, mitochondrial	1944230	Immunological identification of yeast SCO1 protein as a component of the inner mitochondrial membrane.

P34691	FEM3_CAEEL	Sex-determination protein fem-3	10364161	Negative regulation of male development in Caenorhabditis elegans by a protein-protein interaction between TRA-2A and FEM-3.

Q02253	MMSA_RAT	Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial	1527093	CoA-dependent methylmalonate-semialdehyde dehydrogenase, a unique member of the aldehyde dehydrogenase superfamily. cDNA cloning, evolutionary relationships, and tissue distribution.

Q9VC27	NICA_DROME	Nicastrin	11782316	Drosophila nicastrin is essential for the intramembranous cleavage of notch.

P10983	ACT1_CAEEL	Actin-1/3	2795655	Wild-type and mutant actin genes in Caenorhabditis elegans.

Q08157	YOL19_YEAST	Uncharacterized membrane protein YOL019W	15282802	Localization of proteins that are coordinately expressed with Cln2 during the cell cycle.

Q9TW45	PAR1_CAEEL	Serine/threonine-protein kinase par-1	7758115	par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed.

Q02776	TIM50_YEAST	Mitochondrial import inner membrane translocase subunit TIM50	12437924	The mitochondrial presequence translocase: an essential role of Tim50 in directing preproteins to the import channel.

O75448	MED24_HUMAN	Mediator of RNA polymerase II transcription subunit 24	9653119	The TRAP220 component of a thyroid hormone receptor-associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion.

P30557	PE2R3_MOUSE	Prostaglandin E2 receptor EP3 subtype	8223569	Third isoform of the prostaglandin-E-receptor EP3 subtype with different C-terminal tail coupling to both stimulation and inhibition of adenylate cyclase.

P10515	ODP2_HUMAN	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial	15861126	Crystal structure of pyruvate dehydrogenase kinase 3 bound to lipoyl domain 2 of human pyruvate dehydrogenase complex.

Q5VVQ6	OTU1_HUMAN	Ubiquitin thioesterase OTU1	19818707	The otubain YOD1 is a deubiquitinating enzyme that associates with p97 to facilitate protein dislocation from the ER.

Q62406	IRAK1_MOUSE	Interleukin-1 receptor-associated kinase 1	12370331	Mouse pellino-2 modulates IL-1 and lipopolysaccharide signaling.

P48561	TRF5_YEAST	Poly(A) RNA polymerase protein 1	14562095	Global analysis of protein localization in budding yeast.

P18510	IL1RA_HUMAN	Interleukin-1 receptor antagonist protein	9062194	A new cytokine-receptor binding mode revealed by the crystal structure of the IL-1 receptor with an antagonist.

Q9UJ70	NAGK_HUMAN	N-acetyl-D-glucosamine kinase	10824116	Molecular cloning and characterization of murine and human N- acetylglucosamine kinase.

P84047	H4_ASEAQ	Histone H4	10791823	Organization, nucleotide sequence, and chromosomal mapping of a tandemly repeated unit containing the four core histone genes and a 5S rRNA gene in an isopod crustacean species.

Q99594	TEAD3_HUMAN	Transcriptional enhancer factor TEF-5	9148898	Human TEF-5 is preferentially expressed in placenta and binds to multiple functional elements of the human chorionic somatomammotropin- B gene enhancer.

Q12504	RKM4_YEAST	Ribosomal N-lysine methyltransferase 4	18957409	Identification of two SET domain proteins required for methylation of lysine residues in yeast ribosomal protein Rpl42ab.

P41232	P2RY2_RAT	P2Y purinoceptor 2	9437211	Overexpression of P2Y2 purinoceptor in intimal lesions of the rat aorta.

P63241	IF5A1_HUMAN	Eukaryotic translation initiation factor 5A-1	17187778	Eukaryotic translation initiation factor 5A induces apoptosis in colon cancer cells and associates with the nucleus in response to tumour necrosis factor alpha signalling.

Q8BSQ9	PB1_MOUSE	Protein polybromo-1	17640523	An essential switch in subunit composition of a chromatin remodeling complex during neural development.

Q94AH9	FBRL2_ARATH	rRNA 2'-O-methyltransferase fibrillarin 2	10829025	Fibrillarin genes encode both a conserved nucleolar protein and a novel small nucleolar RNA involved in ribosomal RNA methylation in Arabidopsis thaliana.

O00141	SGK1_HUMAN	Serine/threonine-protein kinase Sgk1	9114008	Cloning and characterization of a putative human serine/threonine protein kinase transcriptionally modified during anisotonic and isotonic alterations of cell volume.

Q5T6F0	DCA12_HUMAN	DDB1- and CUL4-associated factor 12	18957058	Novel centrosome protein, TCC52, is a cancer-testis antigen.

P51531	SMCA2_HUMAN	Probable global transcription activator SNF2L2	12837248	The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome.

P15646	FBRL_YEAST	rRNA 2'-O-methyltransferase fibrillarin	2686980	A yeast nucleolar protein related to mammalian fibrillarin is associated with small nucleolar RNA and is essential for viability.

Q9QZ05	E2AK4_MOUSE	Eukaryotic translation initiation factor 2-alpha kinase 4	10504407	Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2alpha kinase.

P92973	CCA1_ARATH	Protein CCA1	16463103	The MYB transcription factor superfamily of Arabidopsis: expression analysis and phylogenetic comparison with the rice MYB family.

Q9P1P5	TAAR2_HUMAN	Trace amine-associated receptor 2	15718104	Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors.

Q9JII6	AK1A1_MOUSE	Alcohol dehydrogenase [NADP+]	10842086	Cloning and developmental expression of mouse aldehyde reductase (AKR1A4).

P53250	TWF1_YEAST	Twinfilin-1	9700161	Regulation of the cortical actin cytoskeleton in budding yeast by twinfilin, a ubiquitous actin monomer-sequestering protein.

Q7ZWK8	OTOP1_DANRE	Otopetrin-1	15480759	Mutated otopetrin 1 affects the genesis of otoliths and the localization of Starmaker in zebrafish.

Q8C6A8	BHE22_MOUSE	Class E basic helix-loop-helix protein 22	17092954	Requirement for Bhlhb5 in the specification of amacrine and cone bipolar subtypes in mouse retina.

Q04048	SYF1_YEAST	Pre-mRNA-splicing factor SYF1	11105756	Functional analyses of interacting factors involved in both pre-mRNA splicing and cell cycle progression in Saccharomyces cerevisiae.

P18507	GBRG2_HUMAN	Gamma-aminobutyric acid receptor subunit gamma-2	2538761	Importance of a novel GABAA receptor subunit for benzodiazepine pharmacology.

Q9WUL6	M3K14_MOUSE	Mitogen-activated protein kinase kinase kinase 14	11239468	NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100.

P59900	EMIL3_MOUSE	EMILIN-3	14706625	Molecular cloning and characterization of a novel gene, EMILIN-5, and its possible involvement in skeletal development.

O75251	NDUS7_HUMAN	NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

P11086	PNMT_HUMAN	Phenylethanolamine N-methyltransferase	3372503	Molecular cloning of cDNA and chromosomal assignment of the gene for human phenylethanolamine N-methyltransferase, the enzyme for epinephrine biosynthesis.

Q92876	KLK6_HUMAN	Kallikrein-6	12878203	Characterization of the enzymatic activity of human kallikrein 6: autoactivation, substrate specificity, and regulation by inhibitors.

Q9NR22	ANM8_HUMAN	Protein arginine N-methyltransferase 8	18320585	Identification of proteins interacting with protein arginine methyltransferase 8: the Ewing sarcoma (EWS) protein binds independent of its methylation state.

P14859	PO2F1_HUMAN	POU domain, class 2, transcription factor 1	10629049	Mutations in host cell factor 1 separate its role in cell proliferation from recruitment of VP16 and LZIP.

P43092	CARP3_CANAL	Candidapepsin-3	8407785	Three distinct secreted aspartyl proteinases in Candida albicans.

P56261	CEBPE_RAT	CCAAT/enhancer-binding protein epsilon	9593684	C/EBPepsilon is a myeloid-specific activator of cytokine, chemokine, and macrophage-colony-stimulating factor receptor genes.

P53088	CTU1_YEAST	Cytoplasmic tRNA 2-thiolation protein 1	14562095	Global analysis of protein localization in budding yeast.

Q9VZU2	HHAT_DROME	Protein-cysteine N-palmitoyltransferase Rasp	11486055	Skinny hedgehog, an acyltransferase required for palmitoylation and activity of the hedgehog signal.

P32519	ELF1_HUMAN	ETS-related transcription factor Elf-1	10207087	Functional and physical interactions between AML1 proteins and an ETS protein, MEF: implications for the pathogenesis of t(8;21)-positive leukemias.

O59673	ATP14_SCHPO	ATP synthase subunit H, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q4U0Y4	NPL1A_XENLA	Nucleosome assembly protein 1-like 1-A	7622566	Members of the NAP/SET family of proteins interact specifically with B-type cyclins.

Q39255	SKP1A_ARATH	SKP1-like protein 1A	18036202	SKP2A, an F-box protein that regulates cell division, is degraded via the ubiquitin pathway.

O94374	IMA2_SCHPO	Importin subunit alpha-2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P0C0R7	RLME_ECOLI	Ribosomal RNA large subunit methyltransferase E	10748051	The FtsJ/RrmJ heat shock protein of Escherichia coli is a 23S ribosomal RNA methyltransferase.

Q9NS75	CLTR2_HUMAN	Cysteinyl leukotriene receptor 2	10913337	The molecular characterization and tissue distribution of the human cysteinyl leukotriene CysLT2 receptor.

Q8LB10	CLPR4_ARATH	ATP-dependent Clp protease proteolytic subunit-related protein 4, chloroplastic	14593120	Clp protease complexes from photosynthetic and non-photosynthetic plastids and mitochondria of plants, their predicted three-dimensional structures, and functional implications.

O64517	MCA4_ARATH	Metacaspase-4	15326173	Type II metacaspases Atmc4 and Atmc9 of Arabidopsis thaliana cleave substrates after arginine and lysine.

P16112	PGCA_HUMAN	Aggrecan core protein	1569188	The structure of aggrecan fragments in human synovial fluid. Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain.

Q9SE83	DRP2A_ARATH	Dynamin-2A	11449048	A new dynamin-like protein, ADL6, is involved in trafficking from the trans-Golgi network to the central vacuole in Arabidopsis.

Q06321	ATG26_YEAST	Sterol 3-beta-glucosyltransferase	14562095	Global analysis of protein localization in budding yeast.

O43133	TBP_CANAL	TATA-box-binding protein	9537374	The TATA-binding protein (TBP) from the human fungal pathogen Candida albicans can complement defects in human and yeast TBPs.

P25389	KCC4_YEAST	Probable serine/threonine-protein kinase KCC4	9925642	Nim1-related kinases coordinate cell cycle progression with the organization of the peripheral cytoskeleton in yeast.

P01138	NGF_HUMAN	Beta-nerve growth factor	6688123	Human beta-nerve growth factor gene sequence highly homologous to that of mouse.

P54253	ATX1_HUMAN	Ataxin-1	16713569	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

Q05785	ENT2_YEAST	Epsin-2	10449404	Yeast epsins contain an essential N-terminal ENTH domain, bind clathrin and are required for endocytosis.

O60437	PEPL_HUMAN	Periplakin	9521878	cDNA cloning, mRNA expression, and chromosomal mapping of human and mouse periplakin genes.

P84267	DAH51_LITDA	Dahlein-5.1	11555873	Bioactive dahlein peptides from the skin secretions of the Australian aquatic frog Litoria dahlii: sequence determination by electrospray mass spectrometry.

P83268	IF2A_RABIT	Eukaryotic translation initiation factor 2 subunit 1	3745199	The NH2-terminal sequence of the alpha and gamma subunits of eukaryotic initiation factor 2 and the phosphorylation site for the heme-regulated eIF-2 alpha kinase.

Q9JMF3	GBG13_MOUSE	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13	10570481	Ggamma13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium.

Q9P0L0	VAPA_HUMAN	Vesicle-associated membrane protein-associated protein A	9657962	Identification of a human homologue of the vesicle-associated membrane protein (VAMP)-associated protein of 33 kDa (VAP-33): a broadly expressed protein that binds to VAMP.

O60313	OPA1_HUMAN	Dynamin-like 120 kDa protein, mitochondrial	11017080	OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28.

P33441	MFT1_YEAST	THO complex subunit MFT1	11060033	A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae.

Q9ZV25	P2C23_ARATH	Probable protein phosphatase 2C 23	16112663	POL and related phosphatases are dosage-sensitive regulators of meristem and organ development in Arabidopsis.

Q06510	TAZ1_YEAST	Lysophosphatidylcholine acyltransferase	14651618	Aberrant cardiolipin metabolism in the yeast taz1 mutant: a model for Barth syndrome.

Q15485	FCN2_HUMAN	Ficolin-2	8576206	A novel human serum lectin with collagen- and fibrinogen-like domains that functions as an opsonin.

Q8SXQ7	PGPLF_DROME	Peptidoglycan-recognition protein LF	12777387	Functional diversity of the Drosophila PGRP-LC gene cluster in the response to lipopolysaccharide and peptidoglycan.

Q03973	HMO1_YEAST	High mobility group protein 1	8969238	Characterization of a high mobility group 1/2 homolog in yeast.

Q08561	IES4_YEAST	Ino eighty subunit 4	14562095	Global analysis of protein localization in budding yeast.

Q9ASS6	CP20B_ARATH	Peptidyl-prolyl cis-trans isomerase CYP20-2, chloroplastic	11826309	Central functions of the lumenal and peripheral thylakoid proteome of Arabidopsis determined by experimentation and genome-wide prediction.

Q940H6	SRK2E_ARATH	Serine/threonine-protein kinase SRK2E	19874541	PYR/PYL/RCAR family members are major in-vivo ABI1 protein phosphatase 2C-interacting proteins in Arabidopsis.

P01720	LV701_HUMAN	Ig lambda chain V-VII region MOT	6780787	Amino acid sequence of the lambda type light chain of a human IgGl myeloma protein (MOT) with unusual antigenicity: a possible new subgroup of lambda chain having a unique N-terminal sequence.

Q12342	LDB17_YEAST	Protein LDB17	14562095	Global analysis of protein localization in budding yeast.

Q86JM7	P2XA_DICDI	P2X receptor A	17625565	An intracellular P2X receptor required for osmoregulation in Dictyostelium discoideum.

P29762	RABP1_HUMAN	Cellular retinoic acid-binding protein 1	1309505	The molecular cloning and expression of two CRABP cDNAs from human skin.

P13010	XRCC5_HUMAN	X-ray repair cross-complementing protein 5	1537839	Identification of proteins binding to interferon-inducible transcriptional enhancers in hematopoietic cells.

Q42400	AAP1_ARATH	Amino acid permease 1	17419840	AAP1 transports uncharged amino acids into roots of Arabidopsis.

Q39255	SKP1A_ARATH	SKP1-like protein 1A	12795696	Protein interaction analysis of SCF ubiquitin E3 ligase subunits from Arabidopsis.

Q9UID6	ZN639_HUMAN	Zinc finger protein 639	16182284	Nuclear translocation of alphaN-catenin by the novel zinc finger transcriptional repressor ZASC1.

Q8MLZ3	PDE5_DICDI	cGMP-dependent 3',5'-cGMP phosphodiesterase A	12429831	Identification of a novel type of cGMP phosphodiesterase that is defective in the chemotactic stmF mutants.

O74443	YJED_SCHPO	SWIRM domain-containing protein C1682.13	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P08593	MSS18_YEAST	Protein MSS18	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

D3Z6P0	PDIA2_MOUSE	Protein disulfide-isomerase A2	9115635	Molecular characterization of a pancreas-specific protein disulfide isomerase, PDIp.

Q12288	YL126_YEAST	Putative glutamine amidotransferase YLR126C	14562095	Global analysis of protein localization in budding yeast.

Q9R257	HEBP1_MOUSE	Heme-binding protein 1	12413491	Characterization of a human and mouse tetrapyrrole-binding protein.

Q14409	GLPK3_HUMAN	Putative glycerol kinase 3	7987308	The glycerol kinase gene family: structure of the Xp gene, and related intronless retroposons.

Q9Y2B9	IPKG_HUMAN	cAMP-dependent protein kinase inhibitor gamma	9218452	Characterization of PKI-gamma, a novel isoform of the protein kinase inhibitor of cAMP-dependent protein kinase.

Q9P799	YN84_SCHPO	Uncharacterized protein P35G2.04c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q92997	DVL3_HUMAN	Segment polarity protein dishevelled homolog DVL-3	15677333	Identification of the Wnt signaling activator leucine-rich repeat in Flightless interaction protein 2 by a genome-wide functional analysis.

Q9USU1	EFC25_SCHPO	Ras guanine nucleotide exchange factor efc25	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P70211	DCC_MOUSE	Netrin receptor DCC	18585357	DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1.

Q9USM3	SFH1_SCHPO	Chromatin structure-remodeling complex subunit sfh1	18622392	Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast.

P0AEU7	SKP_ECOLI	Chaperone protein skp	15304217	Crystal structure of Skp, a prefoldin-like chaperone that protects soluble and membrane proteins from aggregation.

P38959	VPS41_YEAST	Vacuolar protein sorting-associated protein 41	9159129	Characterization of VPS41, a gene required for vacuolar trafficking and high-affinity iron transport in yeast.

Q42400	AAP1_ARATH	Amino acid permease 1	9374550	Topology of NAT2, a prototypical example of a new family of amino acid transporters.

P26045	PTN3_HUMAN	Tyrosine-protein phosphatase non-receptor type 3	19167335	Large-scale structural analysis of the classical human protein tyrosine phosphatome.

Q924A5	S36A1_RAT	Proton-coupled amino acid transporter 1	11390972	Identification and characterization of a lysosomal transporter for small neutral amino acids.

O94687	TAS3_SCHPO	RNA-induced transcriptional silencing complex protein tas3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O75146	HIP1R_HUMAN	Huntingtin-interacting protein 1-related protein	11889126	HIP1 and HIP12 display differential binding to F-actin, AP2, and clathrin. Identification of a novel interaction with clathrin light chain.

P36595	RPAB2_SCHPO	DNA-directed RNA polymerases I, II, and III subunit RPABC2	8088549	The fission yeast Schizosaccharomyces pombe rpb6 gene encodes the common phosphorylated subunit of RNA polymerase and complements a mutation in the corresponding gene of Saccharomyces cerevisiae.

O42606	NGN1_DANRE	Neurogenin-1	12702659	Ash1a and neurogenin1 function downstream of floating head to regulate epiphysial neurogenesis.

P39948	CCND1_RAT	G1/S-specific cyclin-D1	7980531	Calcium modulates the cyclin D1 expression in a rat parathyroid cell line.

Q10290	MAL2_SCHPO	Chromosome segregation protein mal2	12242294	The mal2p protein is an essential component of the fission yeast centromere.

Q9NQG7	HPS4_HUMAN	Hermansky-Pudlak syndrome 4 protein	11836498	Hermansky-Pudlak syndrome is caused by mutations in HPS4, the human homolog of the mouse light-ear gene.

Q99LZ3	SLD5_MOUSE	DNA replication complex GINS protein SLD5	16338220	Identification and characterization of mouse PSF1-binding protein, SLD5.

Q6Q795	VBPC1_HUMAN	Putative viral protein-binding protein C1	16534844	Screening and identification of interacting proteins with hepatitis B virus core protein in leukocytes and cloning of new gene C1.

Q06315	SKG3_YEAST	Protein SKG3	14562095	Global analysis of protein localization in budding yeast.

Q16181	SEPT7_HUMAN	Septin-7	8037772	Molecular cloning of a novel human cDNA homologous to CDC10 in Saccharomyces cerevisiae.

Q78J03	MSRB2_MOUSE	Methionine-R-sulfoxide reductase B2, mitochondrial	14699060	Methionine sulfoxide reduction in mammals: characterization of methionine-R-sulfoxide reductases.

P49757	NUMB_HUMAN	Protein numb homolog	7596406	Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease.

P29590	PML_HUMAN	Probable transcription factor PML	15467728	PML bodies control the nuclear dynamics and function of the CHFR mitotic checkpoint protein.

Q9C8M2	MSRB1_ARATH	Peptide methionine sulfoxide reductase B1, chloroplastic	15923321	The Arabidopsis plastidic methionine sulfoxide reductase B proteins. Sequence and activity characteristics, comparison of the expression with plastidic methionine sulfoxide reductase A, and induction by photooxidative stress.

Q9QYP6	AZI2_MOUSE	5-azacytidine-induced protein 2	10580148	Isolation of the novel cDNA of a gene of which expression is induced by a demethylating stimulus.

Q8N668	COMD1_HUMAN	COMM domain-containing protein 1	15799966	COMMD proteins, a novel family of structural and functional homologs of MURR1.

Q8S8L9	Y2245_ARATH	Uncharacterized TPR repeat-containing protein At2g32450	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q9JLU4	SHAN3_RAT	SH3 and multiple ankyrin repeat domains protein 3	16439662	An architectural framework that may lie at the core of the postsynaptic density.

Q6IWH7	ANO7_HUMAN	Anoctamin-7	14981236	NGEP, a gene encoding a membrane protein detected only in prostate cancer and normal prostate.

Q9HCR9	PDE11_HUMAN	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	10906126	Isolation and characterization of two novel phosphodiesterase PDE11A variants showing unique structure and tissue-specific expression.

Q9LZM8	BLH9_ARATH	BEL1-like homeodomain protein 9	15019989	VAAMANA -- a BEL1-like homeodomain protein, interacts with KNOX proteins BP and STM and regulates inflorescence stem growth in Arabidopsis.

P38393	KIL_ECOLI	Protein kil	8752325	Identification of a new inhibitor of essential division gene ftsZ as the kil gene of defective prophage Rac.

Q13151	ROA0_HUMAN	Heterogeneous nuclear ribonucleoprotein A0	7585247	Isolation and characterization of a novel, low abundance hnRNP protein: A0.

Q99547	MPH6_HUMAN	M-phase phosphoprotein 6	8885239	Identification of novel M phase phosphoproteins by expression cloning.

P52824	DGKQ_HUMAN	Diacylglycerol kinase theta	15632189	Translocation of diacylglycerol kinase theta from cytosol to plasma membrane in response to activation of G protein-coupled receptors and protein kinase C.

Q23MT7	TTL6A_TETTH	Probable beta-tubulin polyglutamylase	15890843	Tubulin polyglutamylase enzymes are members of the TTL domain protein family.

Q9QY93	DCTP1_MOUSE	dCTP pyrophosphatase 1	19220460	Mouse RS21-C6 is a mammalian 2'-deoxycytidine 5'-triphosphate pyrophosphohydrolase that prefers 5-iodocytosine.

P06777	RAD1_YEAST	DNA repair protein RAD1	8621533	Nucleotide excision repair in yeast is mediated by sequential assembly of repair factors and not by a pre-assembled repairosome.

P55084	ECHB_HUMAN	Trifunctional enzyme subunit beta, mitochondrial	7958339	The mitochondrial long-chain trifunctional enzyme: 2-enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase and 3-oxoacyl-CoA thiolase.

P01233	CGHB_HUMAN	Choriogonadotropin subunit beta	1688430	Role of disulfide bond formation in the folding of human chorionic gonadotropin beta subunit into an alpha beta dimer assembly-competent form.

O43678	NDUA2_HUMAN	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

Q92785	REQU_HUMAN	Zinc finger protein ubi-d4	8812431	The d4 gene family in the human genome.

O42860	BUB3_SCHPO	Mitotic checkpoint protein bub3	15509783	Kinetochore targeting of fission yeast Mad and Bub proteins is essential for spindle checkpoint function but not for all chromosome segregation roles of Bub1p.

Q13043	STK4_HUMAN	Serine/threonine-protein kinase 4	16930133	Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled-coil domains, leads to its stabilization and phosphorylation.

P42346	MTOR_RAT	Serine/threonine-protein kinase mTOR	7822316	Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cells.

P16451	ODPX_YEAST	Pyruvate dehydrogenase complex protein X component, mitochondrial	2007123	Disruption and mutagenesis of the Saccharomyces cerevisiae PDX1 gene encoding the protein X component of the pyruvate dehydrogenase complex.

Q10301	YD48_SCHPO	UPF0652 protein C22H10.08	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P24177	ACRD_ECOLI	Probable aminoglycoside efflux pump	10692383	AcrD of Escherichia coli is an aminoglycoside efflux pump.

P19634	SL9A1_HUMAN	Sodium/hydrogen exchanger 1	8283968	Cloning and analysis of the human myocardial Na+/H+ exchanger.

P97315	CSRP1_MOUSE	Cysteine and glycine-rich protein 1	10090149	The LIM protein, CRP1, is a smooth muscle marker.

P37261	FRM2_YEAST	Fatty acid repression mutant protein 2	14562095	Global analysis of protein localization in budding yeast.

Q810B6	ANFY1_MOUSE	Ankyrin repeat and FYVE domain-containing protein 1	10092534	Molecular cloning of a novel 130-kDa cytoplasmic protein, Ankhzn, containing ankyrin repeats hooked to a zinc finger motif.

Q9H7D7	WDR26_HUMAN	WD repeat-containing protein 26	15378603	WDR26: a novel Gbeta-like protein, suppresses MAPK signaling pathway.

P80428	ARP4_YEAST	Actin-related protein 4	10952318	A chromatin remodelling complex involved in transcription and DNA processing.

Q39129	STR16_ARATH	Thiosulfate sulfurtransferase, chloroplastic	15181206	Intracellular localization of Arabidopsis sulfurtransferases.

P36630	CG22_SCHPO	G2/mitotic-specific cyclin cig2	14970237	Requirement of the SCFPop1/Pop2 ubiquitin ligase for degradation of the fission yeast S phase cyclin Cig2.

Q9P805	DCP1_SCHPO	mRNA-decapping enzyme subunit 1	15671491	Decapping reaction of mRNA requires Dcp1 in fission yeast: its characterization in different species from yeast to human.

O43918	AIRE_HUMAN	Autoimmune regulator	19446523	Structure and site-specific recognition of histone H3 by the PHD finger of human autoimmune regulator.

Q07116	SUOX_RAT	Sulfite oxidase, mitochondrial	8276806	Molecular cloning of rat liver sulfite oxidase. Expression of a eukaryotic Mo-pterin-containing enzyme in Escherichia coli.

P35582	FOXA1_MOUSE	Hepatocyte nuclear factor 3-alpha	17220277	Physical and functional interactions between homeodomain NKX2.1 and winged helix/forkhead FOXA1 in lung epithelial cells.

Q15761	NPY5R_HUMAN	Neuropeptide Y receptor type 5	8824284	Identification of a novel hypothalamic neuropeptide Y receptor associated with feeding behavior.

Q12306	SMT3_YEAST	Ubiquitin-like protein SMT3	9312010	The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer.

P17214	EST1_YEAST	Telomere elongation protein EST1	17245108	The nuclear envelope and spindle pole body-associated Mps3 protein bind telomere regulators and function in telomere clustering.

Q16690	DUS5_HUMAN	Dual specificity protein phosphatase 5	7961985	A novel dual specificity phosphatase induced by serum stimulation and heat shock.

P40630	TFAM_MOUSE	Transcription factor A, mitochondrial	8673128	A single mouse gene encodes the mitochondrial transcription factor A and a testis-specific nuclear HMG-box protein.

Q9Y5J9	TIM8B_HUMAN	Mitochondrial import inner membrane translocase subunit Tim8 B	10552927	The human family of deafness/dystonia peptide (DDP) related mitochondrial import proteins.

Q15700	DLG2_HUMAN	Disks large homolog 2	19118189	Preso, a novel PSD-95-interacting FERM and PDZ domain protein that regulates dendritic spine morphogenesis.

P21802	FGFR2_HUMAN	Fibroblast growth factor receptor 2	10618369	Structural interactions of fibroblast growth factor receptor with its ligands.

P06746	DPOLB_HUMAN	DNA polymerase beta	16600869	Arginine methylation regulates DNA polymerase beta.

Q944G9	ALFC2_ARATH	Probable fructose-bisphosphate aldolase 2, chloroplastic	16414959	Tocopherol cyclase (VTE1) localization and vitamin E accumulation in chloroplast plastoglobule lipoprotein particles.

P25870	CLH_DICDI	Clathrin heavy chain	9053320	Clathrin heavy chain is required for spore cell but not stalk cell differentiation in Dictyostelium discoideum.

Q8L5W7	PIF6_ARATH	Transcription factor PIF6	12826627	A link between circadian-controlled bHLH factors and the APRR1/TOC1 quintet in Arabidopsis thaliana.

P49893	WN11B_XENLA	Protein Wnt-11b	19582868	Xenopus Wnt11b is identified as a potential pronephric inducer.

P70662	LDB1_MOUSE	LIM domain-binding protein 1	9391090	The LIM-domain binding protein Ldb1 and its partner LMO2 act as negative regulators of erythroid differentiation.

Q8S8E3	PYL6_ARATH	Abscisic acid receptor PYL6	19898420	A gate-latch-lock mechanism for hormone signalling by abscisic acid receptors.

P24941	CDK2_HUMAN	Cell division protein kinase 2	1653904	Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase.

O88775	EMB_RAT	Embigin	9438341	Embigin, a developmentally expressed member of the immunoglobulin super family, is also expressed during regression of prostate and mammary gland.

Q8R1H0	HOP_MOUSE	Homeodomain-only protein	12297046	Modulation of cardiac growth and development by HOP, an unusual homeodomain protein.

P83147	ASL2_BACSE	Acharan sulfate lyase 2	11322884	Purification and characterization of acharan sulfate lyases, two novel heparinases, from Bacteroides stercoris HJ-15.

O94275	MUG30_SCHPO	Probable E3 ubiquitin-protein ligase mug30	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q7LKY2	ADDH_SCHPO	Adducin-related protein C1289.14	12529438	Global transcriptional responses of fission yeast to environmental stress.

P02708	ACHA_HUMAN	Acetylcholine receptor subunit alpha	18252226	Acetylcholine receptor pathway mutations explain various fetal akinesia deformation sequence disorders.

P26784	RL16A_YEAST	60S ribosomal protein L16-A	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q96IZ0	PAWR_HUMAN	PRKC apoptosis WT1 regulator protein	14627703	AATF inhibits aberrant production of amyloid beta peptide 1-42 by interacting directly with Par-4.

Q9UEF7	KLOT_HUMAN	Klotho	9464267	Identification of the human klotho gene and its two transcripts encoding membrane and secreted klotho protein.

O80805	PHE1_ARATH	MADS-box transcription factor PHERES 1	12815071	The Polycomb-group protein MEDEA regulates seed development by controlling expression of the MADS-box gene PHERES1.

Q9P2A4	ABI3_HUMAN	ABI gene family member 3	11956071	Forced expression of NESH suppresses motility and metastatic dissemination of malignant cells.

Q9Z0F6	RAD9A_MOUSE	Cell cycle checkpoint control protein RAD9A	15983387	Frag1, a homolog of alternative replication factor C subunits, links replication stress surveillance with apoptosis.

Q9N425	CSN3_CAEEL	COP9 signalosome complex subunit 3	12781129	Neddylation and deneddylation of CUL-3 is required to target MEI- 1/katanin for degradation at the meiosis-to-mitosis transition in C. elegans.

Q9VS48	SLX4_DROME	Structure-specific endonuclease subunit SLX4	12504024	Drosophila MUS312 interacts with the nucleotide excision repair endonuclease MEI-9 to generate meiotic crossovers.

Q13474	DRP2_HUMAN	Dystrophin-related protein 2	8640231	Characterization of DRP2, a novel human dystrophin homologue.

Q08820	HXD1_XENLA	Homeobox protein Hox-D1	15196951	The Meis3 protein and retinoid signaling interact to pattern the Xenopus hindbrain.

Q9LDX1	SGS3_ARATH	Protein SUPPRESSOR OF GENE SILENCING 3	15466488	SGS3 and SGS2/SDE1/RDR6 are required for juvenile development and the production of trans-acting siRNAs in Arabidopsis.

Q8K2K6	AGFG1_MOUSE	Arf-GAP domain and FG repeats-containing protein 1	11711676	Lack of acrosome formation in Hrb-deficient mice.

Q8NHY0	B4GN2_HUMAN	Beta-1,4 N-acetylgalactosaminyltransferase 2	12678917	Molecular cloning, gene organization and expression of the human UDP- GalNAc:Neu5Acalpha2-3Galbeta-R beta1,4-N- acetylgalactosaminyltransferase responsible for the biosynthesis of the blood group Sda/Cad antigen: evidence for an unusual extended cytoplasmic domain.

Q22472	RIC3_CAEEL	Resistance to inhibitors of cholinesterase protein 3	15932871	RIC-3 affects properties and quantity of nicotinic acetylcholine receptors via a mechanism that does not require the coiled-coil domains.

P01011	AACT_HUMAN	Alpha-1-antichymotrypsin	14668352	The SANT2 domain of the murine tumor cell DnaJ-like protein 1 human homologue interacts with alpha1-antichymotrypsin and kinetically interferes with its serpin inhibitory activity.

P69423	TATC_ECOLI	Sec-independent protein translocase protein tatC	9546395	A novel and ubiquitous system for membrane targeting and secretion of cofactor-containing proteins.

Q9HBG4	VPP4_HUMAN	V-type proton ATPase 116 kDa subunit a isoform 4	12414817	Novel ATP6V1B1 and ATP6V0A4 mutations in autosomal recessive distal renal tubular acidosis with new evidence for hearing loss.

O54702	CHSTA_RAT	Carbohydrate sulfotransferase 10	9368071	Expression cloning of a cDNA encoding a sulfotransferase involved in the biosynthesis of the HNK-1 carbohydrate epitope.

O15075	DCLK1_HUMAN	Serine/threonine-protein kinase DCLK1	9747029	Expression and chromosomal localization of KIAA0369, a putative kinase structurally related to Doublecortin.

P36017	VPS21_YEAST	Vacuolar protein sorting-associated protein 21	8163546	Role of three rab5-like GTPases, Ypt51p, Ypt52p, and Ypt53p, in the endocytic and vacuolar protein sorting pathways of yeast.

P25365	SED4_YEAST	Putative guanine nucleotide-exchange factor SED4	11168590	Sed4p functions as a positive regulator of Sar1p probably through inhibition of the GTPase activation by Sec23p.

Q8IMN5	GR98D_DROME	Putative gustatory receptor 98d	10710312	Candidate taste receptors in Drosophila.

Q08409	AUS1_YEAST	ATP-dependent permease AUS1	12077145	Transcriptional profiling identifies two members of the ATP-binding cassette transporter superfamily required for sterol uptake in yeast.

P60510	PP4C_HUMAN	Serine/threonine-protein phosphatase 4 catalytic subunit	9837938	Protein phosphatase X interacts with c-Rel and stimulates c- Rel/nuclear factor kappaB activity.

Q5JR59	MTUS2_HUMAN	Microtubule-associated tumor suppressor candidate 2	19543227	TIP150 interacts with and targets MCAK at the microtubule plus ends.

Q91YD1	CXD3_MOUSE	Gap junction delta-3 protein	12681499	Differences in expression patterns between mouse connexin-30.2 (Cx30.2) and its putative human orthologue, connexin-31.9.

Q54QX3	CSN1_DICDI	COP9 signalosome complex subunit 1	16781008	The COP9 signalosome regulates cell proliferation of Dictyostelium discoideum.

Q8VSC3	IPA9_SHIFL	E3 ubiquitin-protein ligase ipaH9.8	18005683	Type III secretion effectors of the IpaH family are E3 ubiquitin ligases.

Q92831	KAT2B_HUMAN	Histone acetyltransferase KAT2B	11568182	Interaction of EVI1 with cAMP-responsive element-binding protein- binding protein (CBP) and p300/CBP-associated factor (P/CAF) results in reversible acetylation of EVI1 and in co-localization in nuclear speckles.

Q00604	NDP_HUMAN	Norrin	8298646	Molecular modelling of the Norrie disease protein predicts a cystine knot growth factor tertiary structure.

O75486	SUPT3_HUMAN	Transcription initiation protein SPT3 homolog	10373431	Identification of TATA-binding protein-free TAFII-containing complex subunits suggests a role in nucleosome acetylation and signal transduction.

Q8WWQ2	HPSE2_HUMAN	Heparanase-2	11027606	Cloning and expression profiling of Hpa2, a novel mammalian heparanase family member.

Q03181	PPARD_HUMAN	Peroxisome proliferator-activated receptor delta	10198642	Molecular recognition of fatty acids by peroxisome proliferator- activated receptors.

Q9D1Q6	ERP44_MOUSE	Endoplasmic reticulum resident protein 44	15652484	Subtype-specific and ER lumenal environment-dependent regulation of inositol 1,4,5-trisphosphate receptor type 1 by ERp44.

P39968	VAC8_YEAST	Vacuolar protein 8	9490720	Vac8p, a vacuolar protein with armadillo repeats, functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole.

P48607	SPZ_DROME	Protein spaetzle	12872120	Binding of the Drosophila cytokine Spatzle to Toll is direct and establishes signaling.

P97849	S27A1_RAT	Long-chain fatty acid transport protein 1	15848183	The subcellular compartmentation of fatty acid transporters is regulated differently by insulin and by AICAR.

P19225	CP270_RAT	Cytochrome P450 2C70	2263625	A different cytochrome P450 form is induced in primary cultures of rat hepatocytes.

Q12019	MDN1_YEAST	Midasin	11583615	Identification of a 60S preribosomal particle that is closely linked to nuclear export.

P41933	ODR7_CAEEL	Nuclear hormone receptor family member odr-7	8601313	odr-10 encodes a seven transmembrane domain olfactory receptor required for responses to the odorant diacetyl.

Q02457	TBF1_YEAST	Protein TBF1	11258704	An activation-independent role of transcription factors in insulator function.

O74551	YCVC_SCHPO	Uncharacterized protein C777.12c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P0AFV8	PSPD_ECOLI	Phage shock protein D	12562786	Interactions between phage-shock proteins in Escherichia coli.

Q5T2W1	NHRF3_HUMAN	Na(+)/H(+) exchange regulatory cofactor NHE-RF3	9461128	Identification and partial characterization of PDZK1: a novel protein containing PDZ interaction domains.

P25847	MSH2_YEAST	DNA mismatch repair protein MSH2	16781730	Mismatch repair factor MSH2-MSH3 binds and alters the conformation of branched DNA structures predicted to form during genetic recombination.

P55009	AIF1_RAT	Allograft inflammatory factor 1	7769138	Cloning and characterization of allograft inflammatory factor-1: a novel macrophage factor identified in rat cardiac allografts with chronic rejection.

P81761	SCIT_MESTA	Lepidopteran-selective toxin	11782289	Isolation and characterization of a novel lepidopteran-selective toxin from the venom of South Indian red scorpion, Mesobuthus tamulus.

Q9BPZ7	SIN1_HUMAN	Target of rapamycin complex 2 subunit MAPKAP1	1849280	Expression of three mammalian cDNAs that interfere with RAS function in Saccharomyces cerevisiae.

Q8IXI1	MIRO2_HUMAN	Mitochondrial Rho GTPase 2	12482879	Atypical Rho GTPases have roles in mitochondrial homeostasis and apoptosis.

Q9ES81	POPD3_MOUSE	Popeye domain-containing protein 3	10882522	Isolation and characterization of the novel popeye gene family expressed in skeletal muscle and heart.

O14013	RRN5_SCHPO	RNA polymerase I-specific transcription initiation factor rrn5	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

Q9P7K9	YOSF_SCHPO	Putative aldehyde dehydrogenase-like protein C21C3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q96EB6	SIRT1_HUMAN	NAD-dependent deacetylase sirtuin-1	11672523	hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase.

P62308	RUXG_HUMAN	Small nuclear ribonucleoprotein G	7744013	snRNP Sm proteins share two evolutionarily conserved sequence motifs which are involved in Sm protein-protein interactions.

Q5XJQ7	OSR1_DANRE	Protein odd-skipped-related 1	18787069	odd skipped related1 reveals a novel role for endoderm in regulating kidney versus vascular cell fate.

P61150	FGF12_RAT	Fibroblast growth factor 12	11376006	Fibroblast growth factor homologous factor 1B binds to the C-terminus of the tetrodotoxin-resistant sodium channel rNav1.9a (NaN).

Q6IA86	ELP2_HUMAN	Elongator complex protein 2	11714725	Purification and characterization of the human elongator complex.

P53420	CO4A4_HUMAN	Collagen alpha-4(IV) chain	7523402	Complete primary structure of the human type IV collagen alpha 4(IV) chain. Comparison with structure and expression of the other alpha (IV) chains.

Q18685	UN112_CAEEL	Protein unc-112	10893272	The UNC-112 gene in Caenorhabditis elegans encodes a novel component of cell-matrix adhesion structures required for integrin localization in the muscle cell membrane.

O15265	ATX7_HUMAN	Ataxin-7	9288099	Cloning of the SCA7 gene reveals a highly unstable CAG repeat expansion.

A2A884	ZEP3_MOUSE	Transcription factor HIVEP3	12001065	Embryonic expression and regulation of the large zinc finger protein KRC.

P19827	ITIH1_HUMAN	Inter-alpha-trypsin inhibitor heavy chain H1	2446322	Isolation and characterization of cDNAs encoding the heavy chain of human inter-alpha-trypsin inhibitor (I alpha TI): unambiguous evidence for multipolypeptide chain structure of I alpha TI.

Q10666	POP1_CAEEL	Protein pop-1	10952315	Distinct beta-catenins mediate adhesion and signalling functions in C. elegans.

P48061	SDF1_HUMAN	Stromal cell-derived factor 1	18802065	Monocyte migration and LFA-1-mediated attachment to brain microvascular endothelia is regulated by SDF-1 alpha through Lyn kinase.

Q9SEU7	TRXM3_ARATH	Thioredoxin M3, chloroplastic	19259774	A novel extended family of stromal thioredoxins.

P29066	ARRB1_RAT	Beta-arrestin-1	12399592	Targeting of cyclic AMP degradation to beta 2-adrenergic receptors by beta-arrestins.

P97946	VEGFD_MOUSE	Vascular endothelial growth factor D	11279005	The specificity of receptor binding by vascular endothelial growth factor-d is different in mouse and man.

Q07418	PEX19_YEAST	Peroxisomal membrane protein import receptor PEX19	9418908	Pex19p, a farnesylated protein essential for peroxisome biogenesis.

O65201	ACOX2_ARATH	Acyl-coenzyme A oxidase 2, peroxisomal	10571860	Long-chain acyl-CoA oxidases of Arabidopsis.

P43628	KI2L3_HUMAN	Killer cell immunoglobulin-like receptor 2DL3	18604210	An essential function for beta-arrestin 2 in the inhibitory signaling of natural killer cells.

Q8GXU8	LPAT1_ARATH	1-acyl-sn-glycerol-3-phosphate acyltransferase 1, chloroplastic	15169931	Loss of plastidic lysophosphatidic acid acyltransferase causes embryo-lethality in Arabidopsis.

Q9QX74	SHAN2_RAT	SH3 and multiple ankyrin repeat domains protein 2	15014124	Linkage of the actin cytoskeleton to the postsynaptic density via direct interactions of Abp1 with the ProSAP/Shank family.

Q9Z2F5	CTBP1_RAT	C-terminal-binding protein 1	19351597	CtBP1/BARS Gly172-->Glu mutant structure: impairing NAD(H)-binding and dimerization.

Q9P0U4	CXXC1_HUMAN	CpG-binding protein	10688657	Cloning of a mammalian transcriptional activator that binds unmethylated CpG motifs and shares a CXXC domain with DNA methyltransferase, human trithorax, and methyl-CpG binding domain protein 1.

Q86LE5	MPSIN_BOOMI	Antimicrobial peptide microplusin	14642886	Cysteine-rich antimicrobial peptides of the cattle tick Boophilus microplus: isolation, structural characterization and tissue expression profile.

Q9UEF7	KLOT_HUMAN	Klotho	11792841	Association of human aging with a functional variant of klotho.

P30993	C5AR_MOUSE	C5a anaphylatoxin chemotactic receptor	1401897	Structural diversity in the extracellular faces of peptidergic G- protein-coupled receptors. Molecular cloning of the mouse C5a anaphylatoxin receptor.

P23593	APOD_RAT	Apolipoprotein D	1695148	Regeneration-associated high level expression of apolipoprotein D mRNA in endoneurial fibroblasts of peripheral nerve.

O82794	AGL24_ARATH	MADS-box protein AGL24	16679456	AGL24, SHORT VEGETATIVE PHASE, and APETALA1 redundantly control AGAMOUS during early stages of flower development in Arabidopsis.

O14773	TPP1_HUMAN	Tripeptidyl-peptidase 1	11054422	The human CLN2 protein/tripeptidyl-peptidase I is a serine protease that autoactivates at acidic pH.

Q00535	CDK5_HUMAN	Cell division protein kinase 5	1639063	A family of human cdc2-related protein kinases.

Q08417	RSB1_YEAST	Sphingoid long-chain base transporter RSB1	16407254	Long chain base tolerance in Saccharomyces cerevisiae is induced by retrograde signals from the mitochondria.

Q92769	HDAC2_HUMAN	Histone deacetylase 2	12670868	Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell- proliferation factor HCF-1.

P32481	IF2G_YEAST	Eukaryotic translation initiation factor 2 subunit gamma	8417348	GCD11, a negative regulator of GCN4 expression, encodes the gamma subunit of eIF-2 in Saccharomyces cerevisiae.

P97478	COQ7_MOUSE	Ubiquinone biosynthesis protein COQ7 homolog	19478076	Reversal of the mitochondrial phenotype and slow development of oxidative biomarkers of aging in long-lived Mclk1+/- mice.

Q9BZD4	NUF2_HUMAN	Kinetochore protein Nuf2	15961401	Architecture of the human Ndc80-Hec1 complex, a critical constituent of the outer kinetochore.

Q92889	XPF_HUMAN	DNA repair endonuclease XPF	8797827	Xeroderma pigmentosum group F caused by a defect in a structure- specific DNA repair endonuclease.

P14737	RAD9_YEAST	DNA repair protein RAD9	2664461	Cloning and sequence analysis of the Saccharomyces cerevisiae RAD9 gene and further evidence that its product is required for cell cycle arrest induced by DNA damage.

P84090	ERH_HUMAN	Enhancer of rudimentary homolog	9074495	The putative cell cycle gene, enhancer of rudimentary, encodes a highly conserved protein found in plants and animals.

P09085	CAD_DROME	Homeotic protein caudal	7743918	Zygotic caudal regulation by hunchback and its role in abdominal segment formation of the Drosophila embryo.

Q9V3P0	PRDX1_DROME	Peroxiredoxin 1	11677042	The peroxiredoxin gene family in Drosophila melanogaster.

P70444	BID_MOUSE	BH3-interacting domain death agonist	20392206	The ubiquitin ligase Itch mediates the antiapoptotic activity of epidermal growth factor by promoting the ubiquitylation and degradation of the truncated C-terminal portion of Bid.

Q9UBC0	HNF6_HUMAN	Hepatocyte nuclear factor 6	10491763	Hepatocyte nuclear factor-6: associations between genetic variability and type II diabetes and between genetic variability and estimates of insulin secretion.

P08458	SPS1_YEAST	Sporulation-specific protein 1	3023934	Characterization and mutational analysis of a cluster of three genes expressed preferentially during sporulation of Saccharomyces cerevisiae.

Q8BM54	MYLIP_MOUSE	E3 ubiquitin-protein ligase MYLIP	19520913	LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor.

P11234	RALB_HUMAN	Ras-related protein Ral-B	19166349	Solution structure and dynamics of the small GTPase RalB in its active conformation: significance for effector protein binding.

Q9UM13	APC10_HUMAN	Anaphase-promoting complex subunit 10	18485873	Mechanism of ubiquitin-chain formation by the human anaphase- promoting complex.

Q9Y807	YN92_SCHPO	Uncharacterized protein C146.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q5Y5T5	ZDHC8_MOUSE	Probable palmitoyltransferase ZDHHC8	15184899	Evidence that the gene encoding ZDHHC8 contributes to the risk of schizophrenia.

Q9BXF6	RFIP5_HUMAN	Rab11 family-interacting protein 5	12470645	Rab11-FIP4 interacts with Rab11 in a GTP-dependent manner and its overexpression condenses the Rab11 positive compartment in HeLa cells.

P60214	SC49B_TITCA	Toxin Tc49b	11821128	Scorpion toxins from Tityus cambridgei that affect Na(+)-channels.

P22607	FGFR3_HUMAN	Fibroblast growth factor receptor 3	7923141	Identification of a novel variant form of fibroblast growth factor receptor 3 (FGFR3 IIIb) in human colonic epithelium.

P54651	HSC90_DICDI	Heat shock cognate 90 kDa protein	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q03497	STE20_YEAST	Serine/threonine-protein kinase STE20	9428767	Interaction of a G-protein beta-subunit with a conserved sequence in Ste20/PAK family protein kinases.

P47742	GBRR2_RAT	Gamma-aminobutyric acid receptor subunit rho-2	12431995	ZIP3, a new splice variant of the PKC-zeta-interacting protein family, binds to GABAC receptors, PKC-zeta, and Kv beta 2.

Q13347	EIF3I_HUMAN	Eukaryotic translation initiation factor 3 subunit I	18599441	Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3.

P25323	MYLKA_DICDI	Myosin light chain kinase A	16546177	Myosin light chain kinase A is activated by cGMP-dependent and cGMP- independent pathways.

O55171	ACOT2_RAT	Acyl-coenzyme A thioesterase 2, mitochondrial	7744868	Very long chain and long chain acyl-CoA thioesterases in rat liver mitochondria. Identification, purification, characterization, and induction by peroxisome proliferators.

O09118	NET1_MOUSE	Netrin-1	18585357	DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1.

Q10472	GALT1_HUMAN	Polypeptide N-acetylgalactosaminyltransferase 1	7592619	Purification and cDNA cloning of a human UDP-N-acetyl-alpha-D- galactosamine:polypeptide N-acetylgalactosaminyltransferase.

Q9JKV2	ICK_MOUSE	Serine/threonine-protein kinase ICK	10699974	Intestinal cell kinase (ICK) localizes to the crypt region and requires a dual phosphorylation site found in map kinases.

Q03280	TOM1_YEAST	E3 ubiquitin-protein ligase TOM1	14562095	Global analysis of protein localization in budding yeast.

Q79PF4	KAIC_SYNE7	Circadian clock protein kinase kaiC	11356188	Two KaiA-binding domains of cyanobacterial circadian clock protein KaiC.

Q07231	ZSC21_MOUSE	Zinc finger and SCAN domain-containing protein 21	1284028	The ubiquitous transactivator Zfp-38 is upregulated during spermatogenesis with differential transcription.

Q54UC9	KIF3_DICDI	Kinesin-related protein 3	18160177	Properties of the Kinesin-1 motor DdKif3 from Dictyostelium discoideum.

Q13625	ASPP2_HUMAN	Apoptosis-stimulating of p53 protein 2	11684014	ASPP proteins specifically stimulate the apoptotic function of p53.

Q12139	YP022_YEAST	Zinc finger protein YPR022C	14562095	Global analysis of protein localization in budding yeast.

Q7M717	TR102_MOUSE	Taste receptor type 2 member 102	11854532	Expression of bitter taste receptors of the T2R family in the gastrointestinal tract and enteroendocrine STC-1 cells.

Q18409	RSP6_CAEEL	Probable splicing factor, arginine/serine-rich 6	10906451	Unique and redundant functions of SR proteins, a conserved family of splicing factors, in Caenorhabditis elegans development.

O15392	BIRC5_HUMAN	Baculoviral IAP repeat-containing protein 5	12773388	HBXIP functions as a cofactor of survivin in apoptosis suppression.

Q02805	ROD1_YEAST	Protein ROD1	12163175	PY motifs of Rod1 are required for binding to Rsp5 and for drug resistance.

P03069	GCN4_YEAST	General control protein GCN4	3530496	Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of yeast.

O70311	NMT2_MOUSE	Glycylpeptide N-tetradecanoyltransferase 2	9506952	A second mammalian N-myristoyltransferase.

Q5JRX3	PREP_HUMAN	Presequence protease, mitochondrial	16849325	Degradation of the amyloid beta-protein by the novel mitochondrial peptidasome, PreP.

O48814	BIK1_ARATH	Serine/threonine-protein kinase BIK1	16339855	The membrane-anchored BOTRYTIS-INDUCED KINASE1 plays distinct roles in Arabidopsis resistance to necrotrophic and biotrophic pathogens.

Q13362	2A5G_HUMAN	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform	17245430	A specific PP2A regulatory subunit, B56gamma, mediates DNA damage- induced dephosphorylation of p53 at Thr55.

Q02948	VPS30_YEAST	Vacuolar protein sorting-associated protein 30	11157979	Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae.

Q5YDB6	CPL1_ARATH	RNA polymerase II C-terminal domain phosphatase-like 1	18506580	The Arabidopsis thaliana carboxyl-terminal domain phosphatase-like 2 regulates plant growth, stress and auxin responses.

P36086	YKH1_YEAST	Uncharacterized oxidoreductase YKL071W	14562095	Global analysis of protein localization in budding yeast.

P23396	RS3_HUMAN	40S ribosomal protein S3	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

O14521	DHSD_HUMAN	Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial	9533030	Cytochrome b in human complex II (succinate-ubiquinone oxidoreductase): cDNA cloning of the components in liver mitochondria and chromosome assignment of the genes for the large (SDHC) and small (SDHD) subunits to 1q21 and 11q23.

P55344	LMIP_HUMAN	Lens fiber membrane intrinsic protein	2584203	Identification of an 18,000-dalton protein in mammalian lens fiber cell membranes.

Q9UKI8	TLK1_HUMAN	Serine/threonine-protein kinase tousled-like 1	10588641	Phosphorylation of SNAP-23 by the novel kinase SNAK regulates t-SNARE complex assembly.

Q84JS6	KNAT6_ARATH	Homeobox protein knotted-1-like 6	16798887	KNAT6: an Arabidopsis homeobox gene involved in meristem activity and organ separation.

Q12345	IES3_YEAST	Ino eighty subunit 3	14562095	Global analysis of protein localization in budding yeast.

Q867Z4	LOLA4_DROME	Longitudinals lacking protein, isoforms F/I/K/T	12538650	A developmentally regulated splice variant from the complex lola locus encoding multiple different zinc finger domain proteins interacts with the chromosomal kinase JIL-1.

Q15021	CND1_HUMAN	Condensin complex subunit 1	10958694	A human condensin complex containing hCAP-C-hCAP-E and CNAP1, a homolog of Xenopus XCAP-D2, colocalizes with phosphorylated histone H3 during the early stage of mitotic chromosome condensation.

P48547	KCNC1_HUMAN	Potassium voltage-gated channel subfamily C member 1	1400413	The Shaw-related potassium channel gene, Kv3.1, on human chromosome 11, encodes the type l K+ channel in T cells.

P32561	RPD3_YEAST	Histone deacetylase RPD3	8873448	Identification of two CyP-40-like cyclophilins in Saccharomyces cerevisiae, one of which is required for normal growth.

P21574	YBX2A_XENLA	Y-box-binding protein 2-A	17942399	CPEB interacts with an ovary-specific eIF4E and 4E-T in early Xenopus oocytes.

P24004	PEX1_YEAST	Peroxisomal ATPase PEX1	16911527	Functional association of the AAA complex and the peroxisomal importomer.

Q9Y2X7	GIT1_HUMAN	ARF GTPase-activating protein GIT1	15182672	Mammalian Scribble forms a tight complex with the betaPIX exchange factor.

Q10240	MU133_SCHPO	Meiotically up-regulated gene 133 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q92835	SHIP1_HUMAN	Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1	8769125	Cloning and expression of a human placenta inositol 1,3,4,5- tetrakisphosphate and phosphatidylinositol 3,4,5-trisphosphate 5- phosphatase.

P22204	DBF2_YEAST	Cell cycle protein kinase DBF2	2181271	The product of the Saccharomyces cerevisiae cell cycle gene DBF2 has homology with protein kinases and is periodically expressed in the cell cycle.

P30501	1C02_HUMAN	HLA class I histocompatibility antigen, Cw-2 alpha chain	2708822	Complete nucleotide sequence of a unique HLA class I C locus product expressed on the human choriocarcinoma cell line BeWo.

Q1MTQ0	BRL1_SCHPO	E3 ubiquitin-protein ligase brl1	17363370	HULC, a histone H2B ubiquitinating complex, modulates heterochromatin independent of histone methylation in fission yeast.

P51659	DHB4_HUMAN	Peroxisomal multifunctional enzyme type 2	9880674	Structure of the gene for the human 17beta-hydroxysteroid dehydrogenase type IV.

Q8TDJ6	DMXL2_HUMAN	DmX-like protein 2	11809763	Rabconnectin-3, a novel protein that binds both GDP/GTP exchange protein and GTPase-activating protein for Rab3 small G protein family.

Q86X95	CIR1_HUMAN	Corepressor interacting with RBPJ 1	19409814	NKAP is a transcriptional repressor of notch signaling and is required for T cell development.

Q42551	SCE1_ARATH	SUMO-conjugating enzyme SCE1	18502747	The PHD domain of plant PIAS proteins mediates sumoylation of bromodomain GTE proteins.

Q94FY7	TOCC_ARATH	Tocopherol cyclase, chloroplastic	16414959	Tocopherol cyclase (VTE1) localization and vitamin E accumulation in chloroplast plastoglobule lipoprotein particles.

O74395	STR1_SCHPO	Siderophore iron transporter 1	12888492	Fep1 represses expression of the fission yeast Schizosaccharomyces pombe siderophore-iron transport system.

P51996	YPT32_YEAST	GTP-binding protein YPT32/YPT11	11785952	Saccharomyces cerevisiae Pra1p/Yip3p interacts with Yip1p and Rab proteins.

Q14164	IKKE_HUMAN	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	10882136	IKK epsilon is part of a novel PMA-inducible IkappaB kinase complex.

P63172	DYLT1_HUMAN	Dynein light chain Tctex-type 1	18647839	D-retrovirus morphogenetic switch driven by the targeting signal accessibility to Tctex-1 of dynein.

O95405	ZFYV9_HUMAN	Zinc finger FYVE domain-containing protein 9	10615055	Structural basis of Smad2 recognition by the Smad anchor for receptor activation.

P40561	SGN1_YEAST	RNA-binding protein SGN1	10764794	The Saccharomyces cerevisiae RNA-binding protein Rbp29 functions in cytoplasmic mRNA metabolism.

A8WGB1	CCBE1_DANRE	Collagen and calcium-binding EGF domain-containing protein 1	19287381	ccbe1 is required for embryonic lymphangiogenesis and venous sprouting.

P54253	ATX1_HUMAN	Ataxin-1	11001934	Identification and characterization of an ataxin-1-interacting protein: A1Up, a ubiquitin-like nuclear protein.

Q9UUN9	ALD2_SPOSA	Aldehyde reductase 2	10583966	Cloning, overexpression, and mutagenesis of the Sporobolomyces salmonicolor AKU4429 gene encoding a new aldehyde reductase, which catalyzes the stereoselective reduction of ethyl 4-chloro-3- oxobutanoate to ethyl (S)-4-chloro-3-hydroxybutanoate.

P21399	ACOC_HUMAN	Cytoplasmic aconitate hydratase	19762596	Control of iron homeostasis by an iron-regulated ubiquitin ligase.

P05067	A4_HUMAN	Amyloid beta A4 protein	11724784	Jun NH2-terminal kinase (JNK) interacting protein 1 (JIP1) binds the cytoplasmic domain of the Alzheimer's beta-amyloid precursor protein (APP).

Q9NUX5	POTE1_HUMAN	Protection of telomeres protein 1	12781132	Human POT1 facilitates telomere elongation by telomerase.

Q12934	BFSP1_HUMAN	Filensin	9628810	Primary sequence, secondary structure, gene structure, and assembly properties suggests that the lens-specific cytoskeletal protein filensin represents a novel class of intermediate filament protein.

P40202	CCS1_YEAST	Superoxide dismutase 1 copper chaperone	9295278	The copper chaperone for superoxide dismutase.

Q6PST4	ATLA1_RAT	Atlastin-1	19665976	A class of dynamin-like GTPases involved in the generation of the tubular ER network.

Q07834	YL032_YEAST	KH domain-containing protein YLL032C	14562095	Global analysis of protein localization in budding yeast.

Q03431	PTH1R_HUMAN	Parathyroid hormone/parathyroid hormone-related peptide receptor	9745456	A homozygous inactivating mutation in the parathyroid hormone/parathyroid hormone-related peptide receptor causing Blomstrand chondrodysplasia.

P35996	RM38_YEAST	54S ribosomal protein L38, mitochondrial	12392552	Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components.

Q12041	MET32_YEAST	Transcriptional regulator MET32	9799240	Multiple transcriptional activation complexes tether the yeast activator Met4 to DNA.

P36603	RIR2_SCHPO	Ribonucleoside-diphosphate reductase small chain	12695334	Cop9/signalosome subunits and Pcu4 regulate ribonucleotide reductase by both checkpoint-dependent and -independent mechanisms.

P55072	TERA_HUMAN	Transitional endoplasmic reticulum ATPase	15362974	A novel UBA and UBX domain protein that binds polyubiquitin and VCP and is a substrate for SAPKs.

Q9HB21	PKHA1_HUMAN	Pleckstrin homology domain-containing family A member 1	14516276	Interaction of the protein tyrosine phosphatase PTPL1 with the PtdIns(3,4)P2-binding adaptor protein TAPP1.

P32478	HS150_YEAST	Cell wall mannoprotein HSP150	10209754	The contribution of the O-glycosylated protein Pir2p/Hsp150 to the construction of the yeast cell wall in wild-type cells and beta 1,6- glucan-deficient mutants.

Q10429	CND3_SCHPO	Condensin complex subunit 3	10485849	Fission yeast condensin complex: essential roles of non-SMC subunits for condensation and Cdc2 phosphorylation of Cut3/SMC4.

Q9W6A8	OP1S2_DANRE	Opsin-1, short-wave-sensitive 2	10349976	Cloning and characterization of six zebrafish photoreceptor opsin cDNAs and immunolocalization of their corresponding proteins.

Q9Y7P0	RISA_SCHPO	Riboflavin synthase alpha chain	14690539	Riboflavin synthase of Schizosaccharomyces pombe. Protein dynamics revealed by 19F NMR protein perturbation experiments.

Q9ZVL6	U603_ARATH	UPF0603 protein At1g54780, chloroplastic	11826309	Central functions of the lumenal and peripheral thylakoid proteome of Arabidopsis determined by experimentation and genome-wide prediction.

Q96DA2	RB39B_HUMAN	Ras-related protein Rab-39B	20159109	Mutations in the small GTPase gene RAB39B are responsible for X- linked mental retardation associated with autism, epilepsy, and macrocephaly.

Q12259	YL108_YEAST	BTB/POZ domain-containing protein YLR108C	14562095	Global analysis of protein localization in budding yeast.

O43809	CPSF5_HUMAN	Cleavage and polyadenylation specificity factor subunit 5	20479262	Structural basis of UGUA recognition by the Nudix protein CFI(m)25 and implications for a regulatory role in mRNA 3' processing.

Q8ITC7	CAPAR_DROME	Neuropeptides capa receptor	12459185	Molecular cloning and functional expression of a Drosophila receptor for the neuropeptides capa-1 and -2.

Q20646	CEP1_CAEEL	Transcription factor cep-1	18627611	Transcriptional profiling in C. elegans suggests DNA damage dependent apoptosis as an ancient function of the p53 family.

Q5U3N7	CHUR_DANRE	Protein Churchill	17980025	Churchill regulates cell movement and mesoderm specification by repressing Nodal signaling.

Q8N163	K1967_HUMAN	Protein KIAA1967	18235502	Negative regulation of the deacetylase SIRT1 by DBC1.

Q02608	RT16_YEAST	37S ribosomal protein S16, mitochondrial	12392552	Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components.

Q9Y6G3	RM42_HUMAN	39S ribosomal protein L42, mitochondrial	11279123	The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present.

Q39032	PLCD1_ARATH	Phosphoinositide phospholipase C 1	11340187	Arabidopsis PLC1 is required for secondary responses to abscisic acid signals.

P20029	GRP78_MOUSE	78 kDa glucose-regulated protein	12065409	A novel type of co-chaperone mediates transmembrane recruitment of DnaK-like chaperones to ribosomes.

P83692	GANA_THIHE	Arabinogalactan endo-1,4-beta-galactosidase	12761390	Structure of two fungal beta-1,4-galactanases: searching for the basis for temperature and pH optimum.

O08901	BUB1_MOUSE	Mitotic checkpoint serine/threonine-protein kinase BUB1	19772675	Inactivating the spindle checkpoint kinase Bub1 during embryonic development results in a global shutdown of proliferation.

Q6WY08	ATLE_AGRAE	Anti-tumor lectin	12757412	An antitumour lectin from the edible mushroom Agrocybe aegerita.

Q13461	FOXE3_HUMAN	Forkhead box protein E3	8825632	Chromosomal localization of six human forkhead genes, freac-1 (FKHL5), -3 (FKHL7), -4 (FKHL8), -5 (FKHL9), -6 (FKHL10), and -8 (FKHL12).

P48381	RFX3_MOUSE	Transcription factor RFX3	17229940	Novel function of the ciliogenic transcription factor RFX3 in development of the endocrine pancreas.

P62851	RS25_HUMAN	40S ribosomal protein S25	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

O43066	PPK30_SCHPO	Serine/threonine-protein kinase ppk30	15821139	Systematic deletion analysis of fission yeast protein kinases.

Q12090	REXO3_YEAST	RNA exonuclease 3	10716935	Three conserved members of the RNase D family have unique and overlapping functions in the processing of 5S, 5.8S, U4, U5, RNase MRP and RNase P RNAs in yeast.

Q9STX5	ENPL_ARATH	Endoplasmin homolog	11867518	SHEPHERD is the Arabidopsis GRP94 responsible for the formation of functional CLAVATA proteins.

Q9LPI7	NAC12_ARATH	NAC domain-containing protein 12	17565617	ANAC012, a member of the plant-specific NAC transcription factor family, negatively regulates xylary fiber development in Arabidopsis thaliana.

P40187	PIG2_YEAST	GSY2-interacting protein PIG2	9046081	Yeast PIG genes: PIG1 encodes a putative type 1 phosphatase subunit that interacts with the yeast glycogen synthase Gsy2p.

P53538	SSU72_YEAST	RNA polymerase II subunit A C-terminal domain phosphatase SSU72	12660165	Ssu72 is a phosphatase essential for transcription termination of snoRNAs and specific mRNAs in yeast.

P50875	SPT20_YEAST	Transcription factor SPT20	9674426	A subset of TAF(II)s are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulation.

Q9LIE5	FHY3_ARATH	Protein FAR-RED ELONGATED HYPOCOTYL 3	17012604	Arabidopsis FHY3 specifically gates phytochrome signaling to the circadian clock.

Q7TMK9	HNRPQ_MOUSE	Heterogeneous nuclear ribonucleoprotein Q	19470752	Three proteins of the U7-specific Sm ring function as the molecular ruler to determine the site of 3'-end processing in mammalian histone pre-mRNA.

P50090	KEL2_YEAST	Kelch repeat-containing protein 2	9786949	Identification of Kel1p, a kelch domain-containing protein involved in cell fusion and morphology in Saccharomyces cerevisiae.

P97612	FAAH1_RAT	Fatty-acid amide hydrolase 1	12459591	Structural adaptations in a membrane enzyme that terminates endocannabinoid signaling.

P50623	UBC9_YEAST	SUMO-conjugating enzyme UBC9	9341106	Ubc9p is the conjugating enzyme for the ubiquitin-like protein Smt3p.

Q59385	COPA_ECOLI	Copper-exporting P-type ATPase A	10639134	CopA: an Escherichia coli Cu(I)-translocating P-type ATPase.

O13953	EAF3_SCHPO	Chromatin modification-related protein eaf3	12773392	Alp13, an MRG family protein, is a component of fission yeast Clr6 histone deacetylase required for genomic integrity.

Q54D08	LST8_DICDI	Protein LST8 homolog	16079174	TOR complex 2 integrates cell movement during chemotaxis and signal relay in Dictyostelium.

P48678	LMNA_MOUSE	Prelamin-A/C	16380439	Coupling of the nucleus and cytoplasm: role of the LINC complex.

Q7Z2C4	SELG_DROME	Glycine-rich selenoprotein	11389138	Selenium metabolism in Drosophila: selenoproteins, selenoprotein mRNA expression, fertility, and mortality.

P35625	TIMP3_HUMAN	Metalloproteinase inhibitor 3	18638486	Structural determinants of the ADAM inhibition by TIMP-3: crystal structure of the TACE-N-TIMP-3 complex.

Q12004	TFB4_YEAST	RNA polymerase II transcription factor B subunit 4	14500720	Revised subunit structure of yeast transcription factor IIH (TFIIH) and reconciliation with human TFIIH.

O35437	TCF21_MOUSE	Transcription factor 21	11287187	Pod-1/Capsulin shows a sex- and stage-dependent expression pattern in the mouse gonad development and represses expression of Ad4BP/SF-1.

Q9USY1	YOW5_SCHPO	Pseudouridine-metabolizing bifunctional protein C1861.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9M076	K6PF6_ARATH	6-phosphofructokinase 6	17485088	Characterisation of the ATP-dependent phosphofructokinase gene family from Arabidopsis thaliana.

Q09624	LOV1_CAEEL	Location of vulva defective 1	12411744	Towards understanding the polycystins.

Q15021	CND1_HUMAN	Condensin complex subunit 1	12138188	Identification of a chromosome-targeting domain in the human condensin subunit CNAP1/hCAP-D2/Eg7.

O59705	COG2_SCHPO	Conserved oligomeric Golgi complex subunit 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O43889	CREB3_HUMAN	Cyclic AMP-responsive element-binding protein 3	10623756	Potential role for luman, the cellular homologue of herpes simplex virus VP16 (alpha gene trans-inducing factor), in herpesvirus latency.

Q9UHL9	GT2D1_HUMAN	General transcription factor II-I repeat domain-containing protein 1	11438732	Repression of TFII-I-dependent transcription by nuclear exclusion.

Q96IY1	NSL1_HUMAN	Kinetochore-associated protein NSL1 homolog	15502821	A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1.

P79149	PININ_CANFA	Pinin	8922384	Characterization of pinin, a novel protein associated with the desmosome-intermediate filament complex.

P35637	FUS_HUMAN	RNA-binding protein FUS	9774382	Oncoprotein TLS interacts with serine-arginine proteins involved in RNA splicing.

Q9FUB7	CHSY_HYPAN	Chalcone synthase	12795704	Benzophenone synthase and chalcone synthase from Hypericum androsaemum cell cultures: cDNA cloning, functional expression, and site-directed mutagenesis of two polyketide synthases.

P34036	DYHC_DICDI	Dynein heavy chain, cytoplasmic	7866389	Molecular characterization of a cytoplasmic dynein from Dictyostelium.

Q9Y619	ORNT1_HUMAN	Mitochondrial ornithine transporter 1	10369256	Hyperornithinaemia-hyperammonaemia-homocitrullinuria syndrome is caused by mutations in a gene encoding a mitochondrial ornithine transporter.

O13370	DED1_SCHPO	ATP-dependent RNA helicase ded1	11711540	The ded1 DEAD box helicase interacts with Chk1 and Cdc2.

O95989	NUDT3_HUMAN	Diphosphoinositol polyphosphate phosphohydrolase 1	9822604	A novel context for the 'MutT' module, a guardian of cell integrity, in a diphosphoinositol polyphosphate phosphohydrolase.

Q02645	HTS_DROME	Protein hu-li tai shao	1340461	hu-li tai shao, a gene required for ring canal formation during Drosophila oogenesis, encodes a homolog of adducin.

Q99N80	SYTL1_MOUSE	Synaptotagmin-like protein 1	11773082	The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain.

P46995	SET2_YEAST	Histone-lysine N-methyltransferase, H3 lysine-36 specific	11839797	Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression.

Q86W42	THOC6_HUMAN	THO complex subunit 6 homolog	18974867	Recruitment of the complete hTREX complex is required for Kaposi's sarcoma-associated herpesvirus intronless mRNA nuclear export and virus replication.

P48432	SOX2_MOUSE	Transcription factor SOX-2	17097055	Inhibition of DNA binding of Sox2 by the SUMO conjugation.

O00291	HIP1_HUMAN	Huntingtin-interacting protein 1	9140394	HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain.

Q63421	PDE1C_RAT	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	7568196	Molecular cloning and characterization of a calmodulin-dependent phosphodiesterase enriched in olfactory sensory neurons.

Q06787	FMR1_HUMAN	Fragile X mental retardation 1 protein	8401578	The FMR-1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation.

P37108	SRP14_HUMAN	Signal recognition particle 14 kDa protein	8196634	A human Alu RNA-binding protein whose expression is associated with accumulation of small cytoplasmic Alu RNA.

O00562	PITM1_HUMAN	Membrane-associated phosphatidylinositol transfer protein 1	9680295	A mammalian homologue of the Drosophila retinal degeneration B gene: implications for the evolution of phototransduction mechanisms.

Q44342	FLGH_AGRT5	Flagellar L-ring protein	9161424	Isolation and characterisation of a linked cluster of genes from Agrobacterium tumefaciens encoding proteins involved in flagellar basal-body structure.

Q10063	EHS1_SCHPO	Calcium influx-promoting protein ehs1	11016847	Schizosaccharomyces pombe ehs1p is involved in maintaining cell wall integrity and in calcium uptake.

P76086	PAAX_ECOLI	Phenylacetic acid degradation operon negative regulatory protein paaX	10766858	Transcriptional regulation of the divergent paa catabolic operons for phenylacetic acid degradation in Escherichia coli.

O95396	MOCS3_HUMAN	Adenylyltransferase and sulfurtransferase MOCS3	15910006	Molybdenum cofactor biosynthesis in humans: identification of a persulfide group in the rhodanese-like domain of MOCS3 by mass spectrometry.

Q9Y2P8	RCL1_HUMAN	RNA 3'-terminal phosphate cyclase-like protein	10790377	Rcl1p, the yeast protein similar to the RNA 3'-phosphate cyclase, associates with U3 snoRNP and is required for 18S rRNA biogenesis.

Q38799	ODPB_ARATH	Pyruvate dehydrogenase E1 component subunit beta, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P40204	RUXG_YEAST	Small nuclear ribonucleoprotein G	9012791	Identification of the proteins of the yeast U1 small nuclear ribonucleoprotein complex by mass spectrometry.

Q8WXF7	ATLA1_HUMAN	Atlastin-1	16815977	Interaction of two hereditary spastic paraplegia gene products, spastin and atlastin, suggests a common pathway for axonal maintenance.

Q03923	ZNF85_HUMAN	Zinc finger protein 85	9839802	Functional analysis of ZNF85 KRAB zinc finger protein, a member of the highly homologous ZNF91 family.

Q9C889	PR1F2_ARATH	PRA1 family protein F2	18583532	The PRA1 gene family in Arabidopsis.

Q8NHZ8	CDC26_HUMAN	Anaphase-promoting complex subunit CDC26	18485873	Mechanism of ubiquitin-chain formation by the human anaphase- promoting complex.

P38632	NSE2_YEAST	E3 SUMO-protein ligase MMS21	15738391	A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization.

P97799	NRSN1_MOUSE	Neurensin-1	9191101	A newly identified membrane protein localized exclusively in intracellular organelles of neurons.

Q56Y85	AMP2B_ARATH	Methionine aminopeptidase 2B	11060042	Identification of eukaryotic peptide deformylases reveals universality of N-terminal protein processing mechanisms.

Q12769	NU160_HUMAN	Nuclear pore complex protein Nup160	11564755	An evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cells.

P50616	TOB1_HUMAN	Protein Tob1	8632892	Tob, a novel protein that interacts with p185erbB2, is associated with anti-proliferative activity.

P63005	LIS1_MOUSE	Platelet-activating factor acetylhydrolase IB subunit alpha	11231056	NudE-L, a novel Lis1-interacting protein, belongs to a family of vertebrate coiled-coil proteins.

P30101	PDIA3_HUMAN	Protein disulfide-isomerase A3	8624847	Cloning, expression and genomic organization of human placental protein disulfide isomerase (previously identified as phospholipase C alpha).

Q03941	CAB5_YEAST	Dephospho-CoA kinase CAB5	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

P22830	HEMH_HUMAN	Ferrochelatase, mitochondrial	2260980	Molecular cloning and sequence analysis of cDNA encoding human ferrochelatase.

Q28104	COPE_BOVIN	Coatomer subunit epsilon	8132710	En bloc incorporation of coatomer subunits during the assembly of COP-coated vesicles.

Q6W3B0	DSG4_RAT	Desmoglein-4	15081105	The lanceolate hair rat phenotype results from a missense mutation in a calcium coordinating site of the desmoglein 4 gene.

Q9ZWB7	PCS2_ARATH	Glutathione gamma-glutamylcysteinyltransferase 2	11684101	Arabidopsis thaliana expresses a second functional phytochelatin synthase.

P43296	RD19A_ARATH	Cysteine proteinase RD19a	8325504	Structure and expression of two genes that encode distinct drought- inducible cysteine proteinases in Arabidopsis thaliana.

Q12154	GET3_YEAST	ATPase GET3	16269340	Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile.

Q15619	OR1C1_HUMAN	Olfactory receptor 1C1	9119360	Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species.

Q9Y048	DTN1_CAEEL	Dystrobrevin-1	11243807	Molecular, genetic and physiological characterisation of dystrobrevin-like (dyb-1) mutants of Caenorhabditis elegans.

Q9QYW3	MOBL3_RAT	Mps one binder kinase activator-like 3	11251078	Molecular cloning and characterization of phocein, a protein found from the Golgi complex to dendritic spines.

Q9NP59	S40A1_HUMAN	Solute carrier family 40 member 1	10747949	A novel mammalian iron-regulated protein involved in intracellular iron metabolism.

Q99613	EIF3C_HUMAN	Eukaryotic translation initiation factor 3 subunit C	18599441	Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3.

Q9YH09	RALBA_XENLA	Ras-related protein ralB-A	10328920	Characterization of Xenopus Ral B and its involvement in F-actin control during early development.

Q9P7V8	MPCP_SCHPO	Probable mitochondrial phosphate carrier protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P40040	THO1_YEAST	Protein THO1	9707445	A novel yeast gene, THO2, is involved in RNA pol II transcription and provides new evidence for transcriptional elongation-associated recombination.

P22309	UD11_HUMAN	UDP-glucuronosyltransferase 1-1	1339448	A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini.

Q5KU26	COL12_HUMAN	Collectin-12	11564734	The membrane-type collectin CL-P1 is a scavenger receptor on vascular endothelial cells.

Q9STP8	ACBP2_ARATH	Acyl-CoA-binding domain-containing protein 2	15159625	Arabidopsis Acyl-CoA-binding protein ACBP2 interacts with an ethylene-responsive element-binding protein, AtEBP, via its ankyrin repeats.

Q86B79	UNK_DROME	RING finger protein unkempt	1339381	The embryonically active gene, unkempt, of Drosophila encodes a Cys3His finger protein.

P46094	XCR1_HUMAN	Chemokine XC receptor 1	9632725	Identification of single C motif-1/lymphotactin receptor XCR1.

P25364	HCM1_YEAST	Forkhead transcription factor HCM1	8441413	A dosage-dependent suppressor of a temperature-sensitive calmodulin mutant encodes a protein related to the fork head family of DNA- binding proteins.

P29510	TBA2_ARATH	Tubulin alpha-2/alpha-4 chain	1498608	The small genome of Arabidopsis contains at least six expressed alpha-tubulin genes.

P25349	YCP4_YEAST	Flavoprotein-like protein YCP4	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

O13919	PST2_SCHPO	Paired amphipathic helix protein pst2	12773392	Alp13, an MRG family protein, is a component of fission yeast Clr6 histone deacetylase required for genomic integrity.

P48508	GSH0_RAT	Glutamate--cysteine ligase regulatory subunit	8104188	Amino acid sequence and function of the light subunit of rat kidney gamma-glutamylcysteine synthetase.

P48016	ATH1_YEAST	Vacuolar acid trehalase	7502577	Isolation and characterization of a novel yeast gene, ATH1, that is required for vacuolar acid trehalase activity.

O15269	SPTC1_HUMAN	Serine palmitoyltransferase 1	9363775	Human and murine serine-palmitoyl-CoA transferase. Cloning, expression and characterization of the key enzyme in sphingolipid synthesis.

P33110	ARLY_ANSAN	Argininosuccinate lyase	16101585	The effect of N-terminal truncation on double-dimer assembly of goose delta-crystallin.

P92177	1433E_DROME	14-3-3 protein epsilon	18256197	In vivo regulation of Yorkie phosphorylation and localization.

P17516	AK1C4_HUMAN	Aldo-keto reductase family 1 member C4	8274401	Molecular cloning of multiple cDNAs encoding human enzymes structurally related to 3 alpha-hydroxysteroid dehydrogenase.

Q9NRQ2	PLS4_HUMAN	Phospholipid scramblase 4	18256029	Identification of Alix-type and non-Alix-type ALG-2-binding sites in human phospholipid scramblase 3: differential binding to an alternatively spliced isoform and amino acid-substituted mutants.

Q13283	G3BP1_HUMAN	Ras GTPase-activating protein-binding protein 1	9889278	Human DNA helicase VIII: a DNA and RNA helicase corresponding to the G3BP protein, an element of the ras transduction pathway.

P12962	CAF20_YEAST	Cap-associated protein CAF20	9707439	Cooperative modulation by eIF4G of eIF4E-binding to the mRNA 5' cap in yeast involves a site partially shared by p20.

O81223	CNBL4_ARATH	Calcineurin B-like protein 4	10590166	Novel protein kinases associated with calcineurin B-like calcium sensors in Arabidopsis.

P40511	SPO22_YEAST	Sporulation-specific protein 22	11101837	The core meiotic transcriptome in budding yeasts.

P41821	MID1_YEAST	Stretch-activated cation channel MID1	10436155	Molecular identification of a eukaryotic, stretch-activated nonselective cation channel.

P25205	MCM3_HUMAN	DNA replication licensing factor MCM3	1549468	Properties of the nuclear P1 protein, a mammalian homologue of the yeast Mcm3 replication protein.

O14718	OPSX_HUMAN	Visual pigment-like receptor peropsin	9275222	Peropsin, a novel visual pigment-like protein located in the apical microvilli of the retinal pigment epithelium.

P38837	NSG1_YEAST	Protein NSG1	16270032	INSIG: a broadly conserved transmembrane chaperone for sterol-sensing domain proteins.

Q9HCU8	DPOD4_HUMAN	DNA polymerase delta subunit 4	15670210	Human Werner helicase interacting protein 1 (WRNIP1) functions as a novel modulator for DNA polymerase delta.

P25604	STP22_YEAST	Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease	15086794	Protein-protein interactions of ESCRT complexes in the yeast Saccharomyces cerevisiae.

P01135	TGFA_HUMAN	Protransforming growth factor alpha	18757723	EGF receptor-independent action of TGF-alpha protects Naked2 from AO7-mediated ubiquitylation and proteasomal degradation.

Q05635	RNH2B_YEAST	Ribonuclease H2 subunit B	14734815	RNase H2 of Saccharomyces cerevisiae is a complex of three proteins.

Q99500	S1PR3_HUMAN	Sphingosine 1-phosphate receptor 3	10617617	Sphingosine 1-phosphate-induced cell proliferation, survival, and related signaling events mediated by G protein-coupled receptors Edg3 and Edg5.

Q9VXF1	PP2B3_DROME	Serine/threonine-protein phosphatase 2B catalytic subunit 3	16860743	The calcineurin regulator sra plays an essential role in female meiosis in Drosophila.

Q8RWZ6	PIN4_ARATH	Auxin efflux carrier component 4	11893337	AtPIN4 mediates sink-driven auxin gradients and root patterning in Arabidopsis.

P0A784	ORN_ECOLI	Oligoribonuclease	9573169	Oligoribonuclease is encoded by a highly conserved gene in the 3'-5' exonuclease superfamily.

Q9HC23	PROK2_HUMAN	Prokineticin-2	11259612	Identification of two prokineticin cDNAs: recombinant proteins potently contract gastrointestinal smooth muscle.

P36123	SA190_YEAST	SIT4-associating protein SAP190	8649382	The SAPs, a new family of proteins, associate and function positively with the SIT4 phosphatase.

P09651	ROA1_HUMAN	Heterogeneous nuclear ribonucleoprotein A1	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

Q92698	RAD54_HUMAN	DNA repair and recombination protein RAD54-like	8805304	Human and mouse homologs of the Saccharomyces cerevisiae RAD54 DNA repair gene: evidence for functional conservation.

Q8VZC3	AL121_ARATH	Delta-1-pyrroline-5-carboxylate dehydrogenase 12A1, mitochondrial	11532180	A nuclear gene encoding mitochondrial delta-1-pyrroline-5-carboxylate dehydrogenase and its potential role in protection from proline toxicity.

Q9VNH6	EXOC4_DROME	Exocyst complex component 4	16351720	Increased synaptic microtubules and altered synapse development in Drosophila sec8 mutants.

Q25519	PRP2_MANSE	Phenoloxidase subunit 2	7644492	Proenzyme of Manduca sexta phenol oxidase: purification, activation, substrate specificity of the active enzyme, and molecular cloning.

Q6BDR8	NSE4_SCHPO	Non-structural maintenance of chromosome element 4	15485909	Rad62 protein functionally and physically associates with the smc5/smc6 protein complex and is required for chromosome integrity and recombination repair in fission yeast.

P42797	RT10_ARATH	40S ribosomal protein S10, mitochondrial	7589523	Transfer of rps10 from the mitochondrion to the nucleus in Arabidopsis thaliana: evidence for RNA-mediated transfer and exon shuffling at the integration site.

Q04949	DYN3_YEAST	Cytoplasmic dynein intermediate light chain DYN3	15642746	The offloading model for dynein function: differential function of motor subunits.

P38887	YH02_YEAST	Uncharacterized protein YHR202W	14562095	Global analysis of protein localization in budding yeast.

P61218	RPAB2_HUMAN	DNA-directed RNA polymerases I, II, and III subunit RPABC2	9852112	Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.

P36655	DSBD_ECOLI	Thiol:disulfide interchange protein dsbD	7628442	Identification and characterization of a new disulfide isomerase-like protein (DsbD) in Escherichia coli.

Q8CA95	PDE10_MOUSE	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	10359840	Isolation and characterization of a dual-substrate phosphodiesterase gene family: PDE10A.

Q06429	1A11_ARATH	1-aminocyclopropane-1-carboxylate synthase-like protein 1	8566772	Characterization of two members (ACS1 and ACS3) of the 1- aminocyclopropane-1-carboxylate synthase gene family of Arabidopsis thaliana.

Q80U72	SCRIB_MOUSE	Protein scribble homolog	16687519	Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals.

P38737	ECM29_YEAST	Proteasome component ECM29	12408819	Multiple associated proteins regulate proteasome structure and function.

Q14542	S29A2_HUMAN	Equilibrative nucleoside transporter 2	9396714	Molecular cloning and characterization of a nitrobenzylthioinosine- insensitive (ei) equilibrative nucleoside transporter from human placenta.

Q9WUV0	ORC5_MOUSE	Origin recognition complex subunit 5	10460412	Identification and characterization of MmORC4 and MmORC5, two subunits of the mouse origin of replication recognition complex.

P31151	S10A7_HUMAN	Protein S100-A7	10026247	Zinc-binding site of an S100 protein revealed. Two crystal structures of Ca2+-bound human psoriasin (S100A7) in the Zn2+-loaded and Zn2+- free states.

P14681	KSS1_YEAST	Mitogen-activated protein kinase KSS1	11583629	Specificity of MAP kinase signaling in yeast differentiation involves transient versus sustained MAPK activation.

P27040	AVR2B_MOUSE	Activin receptor type-2B	1310075	Novel activin receptors: distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors.

P25378	RHEB_YEAST	Rheb-like protein RHB1	10753927	The Saccharomyces cerevisiae Rheb G-protein is involved in regulating canavanine resistance and arginine uptake.

Q23972	SMG_DROME	Protein Smaug	10488336	Smaug, a novel RNA-binding protein that operates a translational switch in Drosophila.

Q8R4E9	CDT1_MOUSE	DNA replication factor Cdt1	15286659	Structural basis for inhibition of the replication licensing factor Cdt1 by geminin.

Q99460	PSMD1_HUMAN	26S proteasome non-ATPase regulatory subunit 1	8816993	cDNA cloning of p112, the largest regulatory subunit of the human 26s proteasome, and functional analysis of its yeast homologue, sen3p.

Q92834	RPGR_HUMAN	X-linked retinitis pigmentosa GTPase regulator	9399904	Spectrum of mutations in the RPGR gene that are identified in 20% of families with X-linked retinitis pigmentosa.

Q9Y709	SKP1_SCHPO	Suppressor of kinetochore protein 1	15147268	Molecular interactions of fission yeast Skp1 and its role in the DNA damage checkpoint.

Q9SIM9	ORE9_ARATH	F-box protein ORE9	11874909	MAX1 and MAX2 control shoot lateral branching in Arabidopsis.

Q91ZS3	CAB45_RAT	45 kDa calcium-binding protein	18355758	The ethanol response gene Cab45 can modulate the impairment elicited by ethanol and ultraviolet in PC12 cells.

Q16584	M3K11_HUMAN	Mitogen-activated protein kinase kinase kinase 11	12529434	A new identity for MLK3 as an NIMA-related, cell cycle-regulated kinase that is localized near centrosomes and influences microtubule organization.

Q13530	SERC3_HUMAN	Serine incorporator 3	10559794	The human TDE gene homologue: localization to 20q13.1-13.3 and variable expression in human tumor cell lines and tissue.

P33181	SUC1_CANAL	Probable sucrose utilization protein SUC1	1729210	A zinc finger protein from Candida albicans is involved in sucrose utilization.

P40989	FKS2_YEAST	1,3-beta-glucan synthase component GSC2	16116083	The Smk1p MAP kinase negatively regulates Gsc2p, a 1,3-beta-glucan synthase, during spore wall morphogenesis in Saccharomyces cerevisiae.

P45970	LIN5_CAEEL	Spindle apparatus protein lin-5	10629219	LIN-5 is a novel component of the spindle apparatus required for chromosome segregation and cleavage plane specification in Caenorhabditis elegans.

Q9ER99	RSCA1_MOUSE	Regulatory solute carrier protein family 1 member 1	15601832	Mice without the regulator gene Rsc1A1 exhibit increased Na+-D- glucose cotransport in small intestine and develop obesity.

Q99380	OST4_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST4	9405463	The highly conserved Stt3 protein is a subunit of the yeast oligosaccharyltransferase and forms a subcomplex with Ost3p and Ost4p.

P06870	KLK1_HUMAN	Kallikrein-1	2686621	Cloning and expression of human salivary-gland kallikrein in Escherichia coli.

Q9SHC2	ARR16_ARATH	Two-component response regulator ARR16	12354925	Characterization of the ARR15 and ARR16 response regulators with special reference to the cytokinin signaling pathway mediated by the AHK4 histidine kinase in roots of Arabidopsis thaliana.

Q12672	RL21B_YEAST	60S ribosomal protein L21-B	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q03067	SGF11_YEAST	SAGA-associated factor 11	15657441	H2B ubiquitin protease Ubp8 and Sgf11 constitute a discrete functional module within the Saccharomyces cerevisiae SAGA complex.

P02765	FETUA_HUMAN	Alpha-2-HS-glycoprotein	3474608	Human alpha 2-HS-glycoprotein: the A and B chains with a connecting sequence are encoded by a single mRNA transcript.

Q06129	TRPG_SULSO	Anthranilate synthase component II	10449718	The crystal structure of anthranilate synthase from Sulfolobus solfataricus: functional implications.

P25656	CDC50_YEAST	Cell division control protein 50	15090616	Cdc50p, a protein required for polarized growth, associates with the Drs2p P-type ATPase implicated in phospholipid translocation in Saccharomyces cerevisiae.

Q6DRF9	WDR55_DANRE	WD repeat-containing protein 55	18769712	WDR55 is a nucleolar modulator of ribosomal RNA synthesis, cell cycle progression, and teleost organ development.

O43521	B2L11_HUMAN	Bcl-2-like protein 11	9430630	Bim: a novel member of the Bcl-2 family that promotes apoptosis.

Q8VIK3	H1FOO_MOUSE	Histone H1oo	11171391	A mammalian oocyte-specific linker histone gene H1oo: homology with the genes for the oocyte-specific cleavage stage histone (cs-H1) of sea urchin and the B4/H1M histone of the frog.

Q9TTY5	PTAFR_BOVIN	Platelet-activating factor receptor	11916258	Comparison of the coding sequence of the platelet-activating factor receptor gene in three species.

O09106	HDAC1_MOUSE	Histone deacetylase 1	9702189	SAP30, a component of the mSin3 corepressor complex involved in N- CoR-mediated repression by specific transcription factors.

Q9JKU3	IF172_RAT	Intraflagellar transport protein 172 homolog	10788441	Identification of a conserved protein that interacts with specific LIM homeodomain transcription factors.

O49432	QRT3_ARATH	Polygalacturonase QRT3	14551328	Microspore separation in the quartet 3 mutants of Arabidopsis is impaired by a defect in a developmentally regulated polygalacturonase required for pollen mother cell wall degradation.

Q8LF80	CKB21_ARATH	Cyclin-dependent kinase B2-1	11432958	Identification of novel cyclin-dependent kinases interacting with the CKS1 protein of Arabidopsis.

Q13740	CD166_HUMAN	CD166 antigen	7760007	Cloning, mapping, and characterization of activated leukocyte-cell adhesion molecule (ALCAM), a CD6 ligand.

O95819	M4K4_HUMAN	Mitogen-activated protein kinase kinase kinase kinase 4	9890973	A novel human STE20-related protein kinase, HGK, that specifically activates the c-Jun N-terminal kinase signaling pathway.

Q60829	PPR1B_MOUSE	Protein phosphatase 1 regulatory subunit 1B	7485543	DARPP-32 promoter directs transgene expression to renal thick ascending limb of loop of Henle.

P33520	RES1_SCHPO	Cell division cycle-related protein res1/sct1	1464317	A new cdc gene required for S phase entry of Schizosaccharomyces pombe encodes a protein similar to the cdc 10+ and SWI4 gene products.

Q80XB4	NRAP_MOUSE	Nebulin-related-anchoring protein	12692149	New N-RAP-binding partners alpha-actinin, filamin and Krp1 detected by yeast two-hybrid screening: implications for myofibril assembly.

Q01860	PO5F1_HUMAN	POU domain, class 5, transcription factor 1	19274063	WWP2 promotes degradation of transcription factor OCT4 in human embryonic stem cells.

Q8UVJ6	VANG2_DANRE	Vang-like protein 2	12105418	Zebrafish trilobite identifies new roles for Strabismus in gastrulation and neuronal movements.

P38820	UBA4_YEAST	Adenylyltransferase and sulfurtransferase UBA4	19145231	Ubiquitin-related modifier Urm1 acts as a sulphur carrier in thiolation of eukaryotic transfer RNA.

Q9Z131	3BP5_MOUSE	SH3 domain-binding protein 5	10339589	Bruton's tyrosine kinase activity is negatively regulated by Sab, the Btk-SH3 domain-binding protein.

P22771	GLRA2_RAT	Glycine receptor subunit alpha-2	1645300	Alternative splicing generates two isoforms of the alpha 2 subunit of the inhibitory glycine receptor.

Q06151	DCPS_YEAST	Scavenger mRNA-decapping enzyme DcpS	12198172	The scavenger mRNA decapping enzyme DcpS is a member of the HIT family of pyrophosphatases.

Q99985	SEM3C_HUMAN	Semaphorin-3C	9405678	Identification of semaphorin E as a non-MDR drug resistance gene of human cancers.

Q54PQ4	GEFA_DICDI	Ras guanine nucleotide exchange factor A	10473630	A novel Ras-interacting protein required for chemotaxis and cyclic adenosine monophosphate signal relay in Dictyostelium.

P01556	CHTB_VIBCH	Cholera enterotoxin subunit B	9232653	Structural studies of receptor binding by cholera toxin mutants.

P04279	SEMG1_HUMAN	Semenogelin-1	2912989	Semenogelin, the predominant protein in human semen. Primary structure and identification of closely related proteins in the male accessory sex glands and on the spermatozoa.

O14576	DC1I1_HUMAN	Cytoplasmic dynein 1 intermediate chain 1	19229290	Dynein light intermediate chain 1 is required for progress through the spindle assembly checkpoint.

Q8C8N3	VWC2_MOUSE	Brorin	18757743	Transcriptome-based systematic identification of extracellular matrix proteins.

O75306	NDUS2_HUMAN	NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

O75081	MTG16_HUMAN	Protein CBFA2T3	16966434	ZNF652, a novel zinc finger protein, interacts with the putative breast tumor suppressor CBFA2T3 to repress transcription.

Q8K1M4	GLIS1_MOUSE	Zinc finger protein GLIS1	12042312	Identification of Glis1, a novel Gli-related, Kruppel-like zinc finger protein containing transactivation and repressor functions.

P18544	ARGD_YEAST	Acetylornithine aminotransferase, mitochondrial	2199330	Escherichia coli and Saccharomyces cerevisiae acetylornithine aminotransferase: evolutionary relationship with ornithine aminotransferase.

P30235	PSUK_ECOLI	Pseudouridine kinase	18591240	Molecular identification of pseudouridine-metabolizing enzymes.

P11711	CP2A1_RAT	Cytochrome P450 2A1	3818621	Rat testosterone 7 alpha-hydroxylase. Isolation, sequence, and expression of cDNA and its developmental regulation and induction by 3-methylcholanthrene.

O14593	RFXK_HUMAN	DNA-binding protein RFXANK	9806546	A gene encoding a novel RFX-associated transactivator is mutated in the majority of MHC class II deficiency patients.

Q9UUA8	YHAG_SCHPO	Uncharacterized protein C409.16c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NWW5	CLN6_HUMAN	Ceroid-lipofuscinosis neuronal protein 6	15265688	CLN6, which is associated with a lysosomal storage disease, is an endoplasmic reticulum protein.

Q93WI9	HD3A_ORYSJ	Protein HEADING DATE 3A	12407188	Hd3a, a rice ortholog of the Arabidopsis FT gene, promotes transition to flowering downstream of Hd1 under short-day conditions.

Q06810	OPY2_YEAST	Protein OPY2	14562095	Global analysis of protein localization in budding yeast.

Q9UTH0	NU132_SCHPO	Nucleoporin nup132	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NZU7	CABP1_HUMAN	Calcium-binding protein 1	9920909	Calbrain, a novel two EF-hand calcium-binding protein that suppresses Ca2+/calmodulin-dependent protein kinase II activity in the brain.

P51449	RORG_HUMAN	Nuclear receptor ROR-gamma	7811290	ROR gamma: the third member of ROR/RZR orphan receptor subfamily that is highly expressed in skeletal muscle.

Q3E833	PCC1_YEAST	Polarized growth chromatin-associated controller 1	16874308	Yeast homolog of a cancer-testis antigen defines a new transcription complex.

P22909	ADA2A_RAT	Alpha-2A adrenergic receptor	1645350	Isolation of rat genomic clones encoding subtypes of the alpha 2- adrenergic receptor. Identification of a unique receptor subtype.

P43246	MSH2_HUMAN	DNA mismatch repair protein Msh2	14676842	Characterization of human exonuclease 1 in complex with mismatch repair proteins, subcellular localization and association with PCNA.

Q9UHI5	LAT2_HUMAN	Large neutral amino acids transporter small subunit 2	12716892	CD98 and intracellular adhesion molecule I regulate the activity of amino acid transporter LAT-2 in polarized intestinal epithelia.

O88551	CLD1_MOUSE	Claudin-1	10601346	Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins.

Q5TZA2	CROCC_HUMAN	Rootletin	16203858	Rootletin forms centriole-associated filaments and functions in centrosome cohesion.

P25375	PRTD_YEAST	Saccharolysin	8307027	Proteinase yscD (oligopeptidase yscD). Structure, function and relationship of the yeast enzyme with mammalian thimet oligopeptidase (metalloendopeptidase, EP 24.15).

Q12018	CDC53_YEAST	Cell division control protein 53	16421250	The F-box protein Dia2 regulates DNA replication.

Q96303	PHT14_ARATH	Inorganic phosphate transporter 1-4	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

P27540	ARNT_HUMAN	Aryl hydrocarbon receptor nuclear translocator	1317062	Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the Ah receptor.

P49815	TSC2_HUMAN	Tuberin	9045618	The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis.

P33993	MCM7_HUMAN	DNA replication licensing factor MCM7	15538388	Interaction between human MCM7 and Rad17 proteins is required for replication checkpoint signaling.

Q03973	HMO1_YEAST	High mobility group protein 1	12374750	Hmo1, an HMG-box protein, belongs to the yeast ribosomal DNA transcription system.

Q54GP3	SPRE_DICDI	Sepiapterin reductase	10987137	Characterization of recombinant Dictyostelium discoideum sepiapterin reductase expressed in E. coli.

O35179	SH3G2_RAT	Endophilin-A1	9238017	The SH3p4/Sh3p8/SH3p13 protein family: binding partners for synaptojanin and dynamin via a Grb2-like Src homology 3 domain.

P62275	RS29_RAT	40S ribosomal protein S29	8441676	Zinc finger-like motifs in rat ribosomal proteins S27 and S29.

Q9ZQ94	COGT3_ARATH	Cytokinin-O-glucosyltransferase 3	15342621	N-glucosylation of cytokinins by glycosyltransferases of Arabidopsis thaliana.

Q7K3L1	MARS_DROME	Guanylate kinase-associated protein mars	15922738	Using Drosophila eye as a model system to characterize the function of mars gene in cell-cycle regulation.

Q12108	YO118_YEAST	Uncharacterized protein YOR118W	14562095	Global analysis of protein localization in budding yeast.

P90980	KPC2_CAEEL	Protein kinase C-like 2	9045693	Structure and expression of the Caenorhabditis elegans protein kinase C2 gene. Origins and regulated expression of a family of Ca2+- activated protein kinase C isoforms.

P80217	IN35_HUMAN	Interferon-induced 35 kDa protein	8288566	IFP 35 is an interferon-induced leucine zipper protein that undergoes interferon-regulated cellular redistribution.

Q9UBK2	PRGC1_HUMAN	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha	17050673	Defects in energy homeostasis in Leigh syndrome French Canadian variant through PGC-1alpha/LRP130 complex.

P49619	DGKG_HUMAN	Diacylglycerol kinase gamma	8034597	Molecular cloning of a diacylglycerol kinase isozyme predominantly expressed in human retina with a truncated and inactive enzyme expression in most other human cells.

O74777	MIS3_SCHPO	Ribosomal RNA assembly protein mis3	10947840	Mis3 with a conserved RNA binding motif is essential for ribosome biogenesis and implicated in the start of cell growth and S phase checkpoint.

O13615	PRP46_SCHPO	Pre-mRNA-splicing factor prp46	10409726	Myb-related fission yeast cdc5p is a component of a 40S snRNP- containing complex and is essential for pre-mRNA splicing.

Q64HY5	SP8_CHICK	Transcription factor Sp8	15358670	Sp8 and Sp9, two closely related buttonhead-like transcription factors, regulate Fgf8 expression and limb outgrowth in vertebrate embryos.

P25086	IL1RA_RAT	Interleukin-1 receptor antagonist protein	1828896	Interleukin 1 receptor antagonist is a member of the interleukin 1 gene family: evolution of a cytokine control mechanism.

Q8UVJ6	VANG2_DANRE	Vang-like protein 2	17239849	Convergence and extension movements mediate the specification and fate maintenance of zebrafish slow muscle precursors.

P0A6I9	COAE_ECOLI	Dephospho-CoA kinase	11292795	Identification of yacE (coaE) as the structural gene for dephosphocoenzyme A kinase in Escherichia coli K-12.

Q9NZQ3	SPN90_HUMAN	NCK-interacting protein with SH3 domain	10648423	Novel SH3 protein encoded by the AF3p21 gene is fused to the mixed lineage leukemia protein in a therapy-related leukemia with t(3;11)(p21;q23).

P11960	ODBA_RAT	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial	2822716	Molecular cloning of a cDNA for the E1 alpha subunit of rat liver branched chain alpha-ketoacid dehydrogenase.

Q9QX98	PTF1A_MOUSE	Pancreas transcription factor 1 subunit alpha	12185368	The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors.

Q8SWR8	ATX2_DROME	Ataxin-2 homolog	12524342	A Drosophila homolog of the polyglutamine disease gene SCA2 is a dosage-sensitive regulator of actin filament formation.

Q9WTN6	S22AL_MOUSE	Solute carrier family 22 member 21	12535646	A third human carnitine/organic cation transporter (OCTN3) as a candidate for the 5q31 Crohn's disease locus (IBD5).

Q9SJN0	ABI5_ARATH	Protein ABSCISIC ACID-INSENSITIVE 5	11287670	A postgermination developmental arrest checkpoint is mediated by abscisic acid and requires the ABI5 transcription factor in Arabidopsis.

O42663	YF89_SCHPO	Uncharacterized but2-like protein C27D7.09c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P61021	RAB5B_MOUSE	Ras-related protein Rab-5B	7789520	Co-operative regulation of endocytosis by three Rab5 isoforms.

P59551	T2R60_HUMAN	Taste receptor type 2 member 60	12584440	Identification and characterization of human taste receptor genes belonging to the TAS2R family.

Q9H2D6	TARA_HUMAN	TRIO and F-actin-binding protein	11148140	Tara, a novel F-actin binding protein, associates with the Trio guanine nucleotide exchange factor and regulates actin cytoskeletal organization.

Q13459	MYO9B_HUMAN	Myosin-IXb	8907710	Human myosin-IXb, an unconventional myosin with a chimerin-like rho/rac GTPase-activating protein domain in its tail.

Q8WZJ8	RPC7_SCHPO	DNA-directed RNA polymerase III subunit rpc31	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P50111	ZDS1_YEAST	Protein ZDS1	8816439	ZDS1 and ZDS2, genes whose products may regulate Cdc42p in Saccharomyces cerevisiae.

Q9NQC7	CYLD_HUMAN	Ubiquitin carboxyl-terminal hydrolase CYLD	15341735	The CAP-Gly domain of CYLD associates with the proline-rich sequence in NEMO/IKKgamma.

Q02769	FDFT_RAT	Squalene synthase	16440058	Lanosterol synthase mutations cause cholesterol deficiency-associated cataracts in the Shumiya cataract rat.

P53192	GET1_YEAST	Golgi to ER traffic protein 1	15909163	Cooperative function of the CHD5-like protein Mdm39p with a P-type ATPase Spf1p in the maintenance of ER homeostasis in Saccharomyces cerevisiae.

Q6IN01	PPR3B_RAT	Protein phosphatase 1 regulatory subunit 3B	7720853	Purification of the hepatic glycogen-associated form of protein phosphatase-1 by microcystin-Sepharose affinity chromatography.

O62090	PRY1_CAEEL	Axin-like protein pry-1	17601533	Two functionally distinct axin-like proteins regulate canonical Wnt signaling in C. elegans.

O75122	CLAP2_HUMAN	CLIP-associating protein 2	19632184	An EB1-binding motif acts as a microtubule tip localization signal.

P22307	NLTP_HUMAN	Non-specific lipid-transfer protein	1703300	Cloning and expression of a cDNA encoding human sterol carrier protein 2.

P53142	VPS73_YEAST	Vacuolar protein sorting-associated protein 73	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

O00329	PK3CD_HUMAN	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform	9113989	P110delta, a novel phosphoinositide 3-kinase in leukocytes.

P41567	EIF1_HUMAN	Eukaryotic translation initiation factor 1	10347211	Cloning and characterization of a human genotoxic and endoplasmic reticulum stress-inducible cDNA that encodes translation initiation factor 1 (eIF1(A121/SUI1)).

P38418	LOX2_ARATH	Lipoxygenase 2, chloroplastic	12938931	Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis.

P35207	SKI2_YEAST	Antiviral helicase SKI2	12769863	An NMD pathway in yeast involving accelerated deadenylation and exosome-mediated 3'-->5' degradation.

Q1MTQ1	TEA2_SCHPO	Kinesin-like protein tea2	11018050	Tea2p is a kinesin-like protein required to generate polarized growth in fission yeast.

Q54CK6	VTI1A_DICDI	Vesicle transport through interaction with t-SNAREs homolog 1A	12175335	Syntaxin 7, syntaxin 8, Vti1 and VAMP7 (vesicle-associated membrane protein 7) form an active SNARE complex for early macropinocytic compartment fusion in Dictyostelium discoideum.

Q96J02	ITCH_HUMAN	E3 ubiquitin-protein ligase Itchy homolog	9647693	Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins.

Q9QXJ1	APBB1_MOUSE	Amyloid beta A4 precursor protein-binding family B member 1	17121854	Essential roles for Fe65, Alzheimer amyloid precursor-binding protein, in the cellular response to DNA damage.

P00533	EGFR_HUMAN	Epidermal growth factor receptor	9103388	Expression of a truncated epidermal growth factor receptor-like protein (TEGFR) in ovarian cancer.

Q96255	SERC_ARATH	Phosphoserine aminotransferase, chloroplastic	9881164	Molecular characterization of plastidic phosphoserine aminotransferase in serine biosynthesis from Arabidopsis.

O88574	SAP30_MOUSE	Histone deacetylase complex subunit SAP30	9702189	SAP30, a component of the mSin3 corepressor complex involved in N- CoR-mediated repression by specific transcription factors.

Q9Z0W5	PACN1_RAT	Protein kinase C and casein kinase substrate in neurons protein 1	9950691	Syndapin I, a synaptic dynamin-binding protein that associates with the neural Wiskott-Aldrich syndrome protein.

P22255	CYSQ_ECOLI	3'(2'),5'-bisphosphate nucleotidase cysQ	16682444	Oligoribonuclease is a common downstream target of lithium-induced pAp accumulation in Escherichia coli and human cells.

P23368	MAOM_HUMAN	NAD-dependent malic enzyme, mitochondrial	1993674	Human NAD(+)-dependent mitochondrial malic enzyme. cDNA cloning, primary structure, and expression in Escherichia coli.

P07347	ARD1_YEAST	N-terminal acetyltransferase A complex catalytic subunit ARD1	14517307	The yeast N(alpha)-acetyltransferase NatA is quantitatively anchored to the ribosome and interacts with nascent polypeptides.

Q90259	ASL1A_DANRE	Achaete-scute homolog 1a	15659486	Wnt1 regulates neurogenesis and mediates lateral inhibition of boundary cell specification in the zebrafish hindbrain.

Q94ID3	IPT1_ARATH	Adenylate isopentenyltransferase 1, chloroplastic	14726522	Distinct isoprenoid origins of cis- and trans-zeatin biosyntheses in Arabidopsis.

Q14500	IRK12_HUMAN	ATP-sensitive inward rectifier potassium channel 12	7859381	Cloning and functional expression of an inwardly rectifying K+ channel from human atrium.

Q9SJQ6	ROS1_ARATH	Protein ROS1	16624880	DEMETER and REPRESSOR OF SILENCING 1 encode 5-methylcytosine DNA glycosylases.

Q9LTK3	HDG7_ARATH	Homeobox-leucine zipper protein HDG7	16778018	Characterization of the class IV homeodomain-leucine zipper gene family in Arabidopsis.

Q9BS26	ERP44_HUMAN	Endoplasmic reticulum resident protein 44	15652484	Subtype-specific and ER lumenal environment-dependent regulation of inositol 1,4,5-trisphosphate receptor type 1 by ERp44.

O23654	VATA_ARATH	V-type proton ATPase catalytic subunit A	20543027	The deubiquitinating enzyme AMSH3 is required for intracellular trafficking and vacuole biogenesis in Arabidopsis thaliana.

P32832	RSC7_YEAST	Chromatin structure-remodeling complex subunit RSC7	16204215	The RSC chromatin remodeling complex bears an essential fungal- specific protein module with broad functional roles.

P60981	DEST_HUMAN	Destrin	8399167	Human actin depolymerizing factor mediates a pH-sensitive destruction of actin filaments.

Q24546	SYN_DROME	Synapsin	8627354	Invertebrate synapsins: a single gene codes for several isoforms in Drosophila.

P10081	IF4A_YEAST	ATP-dependent RNA helicase eIF4A	2648398	An essential yeast protein, encoded by duplicated genes TIF1 and TIF2 and homologous to the mammalian translation initiation factor eIF-4A, can suppress a mitochondrial missense mutation.

O70594	S22A5_RAT	Solute carrier family 22 member 5	10454528	Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter.

Q8BG99	PKNX2_MOUSE	Homeobox protein PKNOX2	12412021	Prep2: cloning and expression of a new prep family member.

Q13522	PPR1A_HUMAN	Protein phosphatase 1 regulatory subunit 1A	11564868	Growth arrest and DNA damage-inducible protein GADD34 assembles a novel signaling complex containing protein phosphatase 1 and inhibitor 1.

Q9LMN6	WAK4_ARATH	Wall-associated receptor kinase 4	11402163	Antisense expression of a cell wall-associated protein kinase, WAK4, inhibits cell elongation and alters morphology.

O08674	RBPJL_MOUSE	Recombining binding protein suppressor of hairless-like protein	9111338	RBP-L, a transcription factor related to RBP-Jkappa.

Q9NXE4	NSMA3_HUMAN	Sphingomyelin phosphodiesterase 4	16517606	Novel tumor necrosis factor-responsive mammalian neutral sphingomyelinase-3 is a C-tail-anchored protein.

Q9UT72	RFP2_SCHPO	E3 ubiquitin-protein ligase complex slx8-rfp subunit rfp2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UKL3	C8AP2_HUMAN	CASP8-associated protein 2	12477726	Tumor necrosis factor alpha receptor- and Fas-associated FLASH inhibit transcriptional activity of the glucocorticoid receptor by binding to and interfering with its interaction with p160 type nuclear receptor coactivators.

Q15398	DLGP5_HUMAN	Disks large-associated protein 5	12527899	Identification of a novel cell cycle regulated gene, HURP, overexpressed in human hepatocellular carcinoma.

P39687	AN32A_HUMAN	Acidic leucine-rich nuclear phosphoprotein 32 family member A	11555662	Granzyme A activates an endoplasmic reticulum-associated caspase- independent nuclease to induce single-stranded DNA nicks.

Q9UT52	MOD21_SCHPO	Gamma-tubulin complex subunit mod21	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8BRT1	CLAP2_MOUSE	CLIP-associating protein 2	11290329	Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts.

P40550	PDR11_YEAST	ATP-dependent permease PDR11	12077145	Transcriptional profiling identifies two members of the ATP-binding cassette transporter superfamily required for sterol uptake in yeast.

Q12021	RAD28_YEAST	Radiation-sensitive protein 28	8830695	Molecular cloning and characterization of Saccharomyces cerevisiae RAD28, the yeast homolog of the human Cockayne syndrome A (CSA) gene.

Q05468	YD333_YEAST	Uncharacterized protein YDR333C	14562095	Global analysis of protein localization in budding yeast.

O88267	ACOT1_RAT	Acyl-coenzyme A thioesterase 1	9490035	Molecular cloning of the peroxisome proliferator-induced 46-kDa cytosolic acyl-CoA thioesterase from mouse and rat liver --recombinant expression in Escherichia coli, tissue expression, and nutritional regulation.

Q13615	MTMR3_HUMAN	Myotubularin-related protein 3	10733931	FYVE-DSP1, a dual-specificity protein phosphatase containing an FYVE domain.

Q8CF90	MAFA_MOUSE	Transcription factor MafA	12917329	Members of the large Maf transcription family regulate insulin gene transcription in islet beta cells.

Q9M077	AUR1_ARATH	Serine/threonine-protein kinase Aurora-1	16028112	Characterization of plant Aurora kinases during mitosis.

O14459	RPB7_SCHPO	DNA-directed RNA polymerase II subunit rpb7	9322754	Gene organization and protein sequence of the small subunits of Schizosaccharomyces pombe RNA polymerase II.

Q54V32	GTAB_DICDI	GATA zinc finger domain-containing protein 2	12871696	A novel developmental mechanism in Dictyostelium revealed in a screen for communication mutants.

Q14164	IKKE_HUMAN	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	16281057	SIKE is an IKK epsilon/TBK1-associated suppressor of TLR3- and virus- triggered IRF-3 activation pathways.

P53060	YGZA_YEAST	UPF0646 protein YGL250W	14562095	Global analysis of protein localization in budding yeast.

P53930	AF9_YEAST	Protein AF-9 homolog	14690608	A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1.

Q9UKK3	PARP4_HUMAN	Poly [ADP-ribose] polymerase 4	10644454	Identification of a novel gene (ADPRTL1) encoding a potential poly(ADP-ribosyl)transferase protein.

Q23977	HEP_DROME	Dual specificity mitogen-activated protein kinase kinase hemipterous	8521475	Hemipterous encodes a novel Drosophila MAP kinase kinase, required for epithelial cell sheet movement.

P93836	HPPD_ARATH	4-hydroxyphenylpyruvate dioxygenase	10198110	Characterization and subcellular compartmentation of recombinant 4- hydroxyphenylpyruvate dioxygenase from Arabidopsis in transgenic tobacco.

P22532	SPR2D_HUMAN	Small proline-rich protein 2D	3133554	Isolation, characterization, and UV-stimulated expression of two families of genes encoding polypeptides of related structure in human epidermal keratinocytes.

P93164	GGH_SOYBN	Gamma-glutamyl hydrolase	8912628	Purification and molecular analysis of an extracellular gamma- glutamyl hydrolase present in young tissues of the soybean plant.

Q14449	GRB14_HUMAN	Growth factor receptor-bound protein 14	8647858	Cloning and characterization of GRB14, a novel member of the GRB7 gene family.

Q06609	RAD51_HUMAN	DNA repair protein RAD51 homolog 1	12427746	Complex formation by the human Rad51B and Rad51C DNA repair proteins and their activities in vitro.

Q07807	PUF3_YEAST	mRNA-binding protein PUF3	17210948	Puf3p, a Pumilio family RNA binding protein, localizes to mitochondria and regulates mitochondrial biogenesis and motility in budding yeast.

P17256	KIME_RAT	Mevalonate kinase	11877411	The structure of a binary complex between a mammalian mevalonate kinase and ATP: insights into the reaction mechanism and human inherited disease.

Q6GQQ9	OTU7B_HUMAN	OTU domain-containing protein 7B	11463333	Isolation and characterization of two novel A20-like proteins.

Q5TAQ9	DCAF8_HUMAN	DDB1- and CUL4-associated factor 8	16949367	A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1.

Q50H32	GRCR1_MOUSE	Glutaredoxin domain-containing cysteine-rich protein 1	20137774	Mutations in Grxcr1 are the basis for inner ear dysfunction in the pirouette mouse.

P60766	CDC42_MOUSE	Cell division control protein 42 homolog	8464478	Oncogene ect2 is related to regulators of small GTP-binding proteins.

Q8LDV3	Y4320_ARATH	Uncharacterized protein At4g13200, chloroplastic	16461379	Protein profiling of plastoglobules in chloroplasts and chromoplasts. A surprising site for differential accumulation of metabolic enzymes.

O44249	PRP1_MANSE	Phenoloxidase subunit 1	9474780	Subunit composition of pro-phenol oxidase from Manduca sexta: molecular cloning of subunit ProPO-P1.

Q95ST2	WLS_DROME	Protein wntless	17108000	Sprinter: a novel transmembrane protein required for Wg secretion and signaling.

O13974	OTU1_SCHPO	Putative ubiquitin thioesterase otu1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O75843	AP1G2_HUMAN	AP-1 complex subunit gamma-like 2	9733768	Identification and characterization of novel clathrin adaptor-related proteins.

Q99712	IRK15_HUMAN	ATP-sensitive inward rectifier potassium channel 15	8995301	Cloning and characterization of two K+ inward rectifier (Kir) 1.1 potassium channel homologs from human kidney (Kir1.2 and Kir1.3).

Q9PWJ5	ID2A_XENLA	DNA-binding protein inhibitor ID-2-A	14651922	Cloning and characterization of Xenopus Id4 reveals differing roles for Id genes.

Q8VY10	UBC24_ARATH	Probable ubiquitin-conjugating enzyme E2 24	18390805	Regulatory network of MicroRNA399 and PHO2 by systemic signaling.

Q12114	CHS5_YEAST	Chitin biosynthesis protein CHS5	16498409	Arf1p, Chs5p and the ChAPs are required for export of specialized cargo from the Golgi.

P13597	ICAM1_MOUSE	Intercellular adhesion molecule 1	2479693	Isolation of the murine intercellular adhesion molecule 1 (ICAM-1) gene. ICAM-1 enhances antigen-specific T cell activation.

Q12234	RUD3_YEAST	GRIP domain-containing protein RUD3	10562277	Sec34p, a protein required for vesicle tethering to the yeast Golgi apparatus, is in a complex with Sec35p.

P22745	BAM_DROME	Protein bag-of-marbles	2279698	Bag-of-marbles: a Drosophila gene required to initiate both male and female gametogenesis.

P36125	GMH1_YEAST	Protein GMH1	12808035	A novel Golgi membrane protein is a partner of the ARF exchange factors Gea1p and Gea2p.

P22525	YCBB_ECOLI	Probable L,D-transpeptidase YcbB	18456808	Identification of the L,D-transpeptidases for peptidoglycan cross- linking in Escherichia coli.

O75197	LRP5_HUMAN	Low-density lipoprotein receptor-related protein 5	15024691	Mutations in LRP5 or FZD4 underlie the common familial exudative vitreoretinopathy locus on chromosome 11q.

Q8GWW7	AGUA_ARATH	Agmatine deiminase	12782327	Identification and characterization of plant agmatine iminohydrolase, the last missing link in polyamine biosynthesis of plants.

Q12127	CCW12_YEAST	Covalently-linked cell wall protein 12	10322008	Deletion of new covalently linked cell wall glycoproteins alters the electrophoretic mobility of phosphorylated wall components of Saccharomyces cerevisiae.

P11233	RALA_HUMAN	Ras-related protein Ral-A	20005108	RalA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling.

P19526	FUT1_HUMAN	Galactoside 2-alpha-L-fucosyltransferase 1	2118655	Molecular cloning, sequence, and expression of a human GDP-L- fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase cDNA that can form the H blood group antigen.

Q8WXF8	DEDD2_HUMAN	DNA-binding death effector domain-containing protein 2	11741985	Identification and characterization of DEDD2, a death effector domain-containing protein.

P40462	TM108_YEAST	Protein TMA108	16702403	Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes.

P38707	SYNC_YEAST	Asparaginyl-tRNA synthetase, cytoplasmic	9605503	Identification of YHR019 in Saccharomyces cerevisiae chromosome VIII as the gene for the cytosolic asparaginyl-tRNA synthetase.

P76216	ASTB_ECOLI	N-succinylarginine dihydrolase	9696779	Arginine catabolism and the arginine succinyltransferase pathway in Escherichia coli.

P08902	LECA_DIOGR	Lectin alpha chain	10082964	Molecular characterization and crystallization of Diocleinae lectins.

O43088	RBA50_SCHPO	RNA polymerase II-associated protein rba50	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q64327	MEA1_MOUSE	Male-enhanced antigen 1	12444059	Male-enhanced antigen-1 gene flanked by two overlapping genes is expressed in late spermatogenesis.

O74429	VIP1_SCHPO	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P40990	MSS2_YEAST	Protein MSS2, mitochondrial	11950926	Cox18p is required for export of the mitochondrially encoded Saccharomyces cerevisiae Cox2p C-tail and interacts with Pnt1p and Mss2p in the inner membrane.

Q9UIC8	LCMT1_HUMAN	Leucine carboxyl methyltransferase 1	10600115	Purification of porcine brain protein phosphatase 2A leucine carboxyl methyltransferase and cloning of the human homologue.

P75736	YBFF_ECOLI	Esterase ybfF	15808744	Enzyme genomics: application of general enzymatic screens to discover new enzymes.

Q38879	TRXH2_ARATH	Thioredoxin H2	7777559	Evidence for five divergent thioredoxin h sequences in Arabidopsis thaliana.

Q8BH60	GOPC_MOUSE	Golgi-associated PDZ and coiled-coil motif-containing protein	12372286	A novel protein complex linking the delta 2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice.

O55207	SYNJ2_RAT	Synaptojanin-2	9388224	Synaptojanin 2, a novel synaptojanin isoform with a distinct targeting domain and expression pattern.

Q9VI93	RN_DROME	Zinc finger protein rotund	11874922	Control of Drosophila imaginal disc development by rotund and roughened eye: differentially expressed transcripts of the same gene encoding functionally distinct zinc finger proteins.

B2RTY4	MYO9A_HUMAN	Myosin-IXa	8022818	Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types.

Q5JS13	RGPS1_HUMAN	Ras-specific guanine nucleotide-releasing factor RalGPS1	10747847	Identification and characterization of a new family of guanine nucleotide exchange factors for the ras-related GTPase Ral.

P25569	GID7_YEAST	Glucose-induced degradation protein 7	12686616	Catabolite degradation of fructose-1,6-bisphosphatase in the yeast Saccharomyces cerevisiae: a genome-wide screen identifies eight novel GID genes and indicates the existence of two degradation pathways.

Q01750	T2FB_RAT	General transcription factor IIF subunit 2	1429731	The carboxyl terminus of RAP30 is similar in sequence to region 4 of bacterial sigma factors and is required for function.

P07261	GCR1_YEAST	Glycolytic genes transcriptional activator GCR1	3547083	The GCR1 gene encodes a positive transcriptional regulator of the enolase and glyceraldehyde-3-phosphate dehydrogenase gene families in Saccharomyces cerevisiae.

Q12328	TIM22_YEAST	Mitochondrial import inner membrane translocase subunit TIM22	10648604	Tim18p, a new subunit of the TIM22 complex that mediates insertion of imported proteins into the yeast mitochondrial inner membrane.

P62258	1433E_HUMAN	14-3-3 protein epsilon	15722337	Phosphorylation of grb10 regulates its interaction with 14-3-3.

Q12220	UTP12_YEAST	U3 small nucleolar RNA-associated protein 12	12068309	A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis.

Q9VW71	FAT2_DROME	Fat-like cadherin-related tumor suppressor homolog	19906848	The cadherin Fat2 is required for planar cell polarity in the Drosophila ovary.

P53615	CAN_YEAST	Carbonic anhydrase	15096093	Complementation of the yeast deletion mutant DeltaNCE103 by members of the beta class of carbonic anhydrases is dependent on carbonic anhydrase activity rather than on antioxidant activity.

P21524	RIR1_YEAST	Ribonucleoside-diphosphate reductase large chain 1	10716984	Yeast ribonucleotide reductase has a heterodimeric iron-radical- containing subunit.

O74635	RPB9_SCHPO	DNA-directed RNA polymerase II subunit RPB9	9852944	Identification of the gene and the protein of RNA polymerase II subunit 9 (Rpb9) from the fission yeast Schizosaccharomyces pombe.

Q6NYV8	LCLT1_DANRE	Lysocardiolipin acyltransferase 1	18388326	An acyltransferase controls the generation of hematopoietic and endothelial lineages in zebrafish.

P12724	ECP_HUMAN	Eosinophil cationic protein	2745977	Eosinophil cationic protein cDNA. Comparison with other toxic cationic proteins and ribonucleases.

O94244	HAT2_SCHPO	Histone acetyltransferase type B subunit 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P60228	EIF3E_HUMAN	Eukaryotic translation initiation factor 3 subunit E	9295280	The translation initiation factor eIF3-p48 subunit is encoded by int- 6, a site of frequent integration by the mouse mammary tumor virus genome.

O49675	CCD4_ARATH	Probable carotenoid cleavage dioxygenase 4, chloroplastic	16461379	Protein profiling of plastoglobules in chloroplasts and chromoplasts. A surprising site for differential accumulation of metabolic enzymes.

Q9NX70	MED29_HUMAN	Mediator of RNA polymerase II transcription subunit 29	14638676	A mammalian mediator subunit that shares properties with Saccharomyces cerevisiae mediator subunit Cse2.

P53073	EMC4_YEAST	ER membrane protein complex subunit 4	14562095	Global analysis of protein localization in budding yeast.

P14841	CYTC_RAT	Cystatin-C	2689174	The cDNA structure and expression analysis of the genes for the cysteine proteinase inhibitor cystatin C and for beta 2-microglobulin in rat brain.

Q12791	KCMA1_HUMAN	Calcium-activated potassium channel subunit alpha-1	10692449	Cloning and functional characterization of novel large conductance calcium-activated potassium channel beta subunits, hKCNMB3 and hKCNMB4.

O75928	PIAS2_HUMAN	E3 SUMO-protein ligase PIAS2	11477070	DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor.

Q9NVH2	INT7_HUMAN	Integrator complex subunit 7	16239144	Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.

Q9Y4C1	KDM3A_HUMAN	Lysine-specific demethylase 3A	16603237	JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor.

Q10426	RIK1_SCHPO	Chromatin modification-related protein rik1	8138176	Mutations in rik1, clr2, clr3 and clr4 genes asymmetrically derepress the silent mating-type loci in fission yeast.

P36060	MCR1_YEAST	NADH-cytochrome b5 reductase 2	16689936	Integral membrane proteins in the mitochondrial outer membrane of Saccharomyces cerevisiae.

Q6DUW7	IDL3_ARATH	Protein IDA-LIKE 3	18660431	The EPIP peptide of INFLORESCENCE DEFICIENT IN ABSCISSION is sufficient to induce abscission in arabidopsis through the receptor- like kinases HAESA and HAESA-LIKE2.

Q08955	CSM4_YEAST	Chromosome segregation in meiosis protein 4	18585352	Rapid telomere movement in meiotic prophase is promoted by NDJ1, MPS3, and CSM4 and is modulated by recombination.

P12527	LOX5_RAT	Arachidonate 5-lipoxygenase	3417684	Isolation and characterization of a cDNA clone encoding rat 5- lipoxygenase.

Q8LK56	DME_ARATH	Transcriptional activator DEMETER	12150995	DEMETER, a DNA glycosylase domain protein, is required for endosperm gene imprinting and seed viability in Arabidopsis.

Q9Y871	FAEB_PIREQ	Feruloyl esterase B	10493932	A modular cinnamoyl ester hydrolase from the anaerobic fungus Piromyces equi acts synergistically with xylanase and is part of a multiprotein cellulose-binding cellulase-hemicellulase complex.

O35657	NEUR1_MOUSE	Sialidase-1	9425240	A point mutation in the neu-1 locus causes the neuraminidase defect in the SM/J mouse.

P35222	CTNB1_HUMAN	Catenin beta-1	12408824	The crystal structure of the beta-catenin/ICAT complex reveals the inhibitory mechanism of ICAT.

P09950	HEM1_YEAST	5-aminolevulinate synthase, mitochondrial	3023841	The nine amino-terminal residues of delta-aminolevulinate synthase direct beta-galactosidase into the mitochondrial matrix.

O15273	TELT_HUMAN	Telethonin	11842093	Calsarcin-3, a novel skeletal muscle-specific member of the calsarcin family, interacts with multiple Z-disc proteins.

P53950	VAC7_YEAST	Vacuolar segregation protein 7	19037259	VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P(2) in yeast and mouse.

P20396	TRH_HUMAN	Prothyroliberin	2126343	Cloning and structure of human genomic DNA and hypothalamic cDNA encoding human prepro thyrotropin-releasing hormone.

Q04116	YHP1_YEAST	Homeobox protein YHP1	12464633	Conserved homeodomain proteins interact with MADS box protein Mcm1 to restrict ECB-dependent transcription to the M/G1 phase of the cell cycle.

C0LGW6	ERL1_ARATH	LRR receptor-like serine/threonine-protein kinase ERL1	16002616	Stomatal patterning and differentiation by synergistic interactions of receptor kinases.

O94316	SN114_SCHPO	114 kDa U5 small nuclear ribonucleoprotein component homolog	10409726	Myb-related fission yeast cdc5p is a component of a 40S snRNP- containing complex and is essential for pre-mRNA splicing.

P28566	5HT1E_HUMAN	5-hydroxytryptamine receptor 1E	1733778	Molecular cloning of a human gene (S31) encoding a novel serotonin receptor mediating inhibition of adenylyl cyclase.

Q9XZT1	MED18_DROME	Mediator of RNA polymerase II transcription subunit 18	11259581	Drosophila Mediator complex is broadly utilized by diverse gene- specific transcription factors at different types of core promoters.

Q8IVV2	LOXH1_HUMAN	Lipoxygenase homology domain-containing protein 1	19732867	Mutations in LOXHD1, an evolutionarily conserved stereociliary protein, disrupt hair cell function in mice and cause progressive hearing loss in humans.

Q8VCQ6	SMS1_MOUSE	Phosphatidylcholine:ceramide cholinephosphotransferase 1	16226406	The mouse sphingomyelin synthase 1 (SMS1) gene is alternatively spliced to yield multiple transcripts and proteins.

P32527	ZUO1_YEAST	Zuotin	15456889	The ribosome-bound chaperones RAC and Ssb1/2p are required for accurate translation in Saccharomyces cerevisiae.

O75689	ADAP1_HUMAN	Arf-GAP with dual PH domain-containing protein 1	10448098	Molecular cloning and functional characterization of a human homologue of centaurin-alpha.

P30793	GCH1_HUMAN	GTP cyclohydrolase 1	12176133	GTP cyclohydrolase I gene transfer augments intracellular tetrahydrobiopterin in human endothelial cells: effects on nitric oxide synthase activity, protein levels and dimerisation.

Q9EQD0	FZD5_MOUSE	Frizzled-5	11520064	Identification of a PDZ domain containing Golgi protein, GOPC, as an interaction partner of frizzled.

Q06636	GPI11_YEAST	Glycosylphosphatidylinositol anchor biosynthesis protein 11	10793139	Glycosylphosphatidylinositol biosynthesis defects in Gpi11p- and Gpi13p-deficient yeast suggest a branched pathway and implicate gpi13p in phosphoethanolamine transfer to the third mannose.

Q02769	FDFT_RAT	Squalene synthase	1400448	Molecular cloning, expression, and characterization of the cDNA for the rat hepatic squalene synthase.

Q80ZG6	BBC3_RAT	Bcl-2-binding component 3	12787069	Bcl-2-related protein family gene expression during oligodendroglial differentiation.

Q3TIV5	ZC3HF_MOUSE	Zinc finger CCCH domain-containing protein 15	10880228	Subtraction cloning and initial characterization of novel EPO- immediate response genes.

Q63505	TF3C1_RAT	General transcription factor 3C polypeptide 1	8164661	Cloning and characterization of an evolutionarily divergent DNA- binding subunit of mammalian TFIIIC.

P32457	CDC3_YEAST	Cell division control protein 3	9813094	Polymerization of purified yeast septins: evidence that organized filament arrays may not be required for septin function.

P62837	UB2D2_HUMAN	Ubiquitin-conjugating enzyme E2 D2	15001359	An altered-specificity ubiquitin-conjugating enzyme/ubiquitin-protein ligase pair.

P46674	SAC3_YEAST	Nuclear mRNA export protein SAC3	12411502	The mRNA export machinery requires the novel Sac3p-Thp1p complex to dock at the nucleoplasmic entrance of the nuclear pores.

P61081	UBC12_HUMAN	NEDD8-conjugating enzyme Ubc12	15694336	Structural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1.

C7DZK3	CRA1A_DANRE	Collagen alpha-1(XXVII) chain A	20041163	Critical early roles for col27a1a and col27a1b in zebrafish notochord morphogenesis, vertebral mineralization and post-embryonic axial growth.

P42073	REF2_YEAST	RNA end formation protein 2	12819204	Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-ends.

Q9QX98	PTF1A_MOUSE	Pancreas transcription factor 1 subunit alpha	11318877	p48 subunit of mouse PTF1 binds to RBP-Jkappa/CBF-1, the intracellular mediator of Notch signalling, and is expressed in the neural tube of early stage embryos.

Q8VBZ3	CLPT1_MOUSE	Cleft lip and palate transmembrane protein 1 homolog	9218588	Transgenic expression of a novel thymic epithelial cell antigen stimulates aberrant development of thymocytes.

P13010	XRCC5_HUMAN	X-ray repair cross-complementing protein 5	15075319	Positive and negative modulation of the transcriptional activity of the ETS factor ESE-1 through interaction with p300, CREB-binding protein, and Ku 70/86.

Q9P7F8	GET3_SCHPO	ATPase get3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9VI10	SMD2_DROME	Probable small nuclear ribonucleoprotein Sm D2	17412918	Genes required for mitotic spindle assembly in Drosophila S2 cells.

P87056	YDJ8_SCHPO	Abhydrolase domain-containing protein C57A10.08c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q6R005	DLG4_DANRE	Disks large homolog 4	14758365	In vivo imaging of synapse formation on a growing dendritic arbor.

Q8S9F2	PCYAA_EUGGR	Photoactivated adenylate cyclase subunit alpha	11875575	A blue-light-activated adenylyl cyclase mediates photoavoidance in Euglena gracilis.

P47898	5HT5A_HUMAN	5-hydroxytryptamine receptor 5A	7988681	Cloning and characterisation of the human 5-HT5A serotonin receptor.

P85212	PROP2_GALME	Proline-rich antimicrobial peptide 2	17194500	Purification and characterization of eight peptides from Galleria mellonella immune hemolymph.

P48439	OST3_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3	7622558	Functional characterization of Ost3p. Loss of the 34-kD subunit of the Saccharomyces cerevisiae oligosaccharyltransferase results in biased underglycosylation of acceptor substrates.

Q08926	UIP4_YEAST	ULP1-interacting protein 4	16407407	Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins.

Q02724	ULP1_YEAST	Ubiquitin-like-specific protease 1	10882122	Ulp1-SUMO crystal structure and genetic analysis reveal conserved interactions and a regulatory element essential for cell growth in yeast.

P36052	MIDA_YEAST	Protein midA homolog	14562095	Global analysis of protein localization in budding yeast.

P08779	K1C16_HUMAN	Keratin, type I cytoskeletal 16	15731013	Identification of trichoplein, a novel keratin filament-binding protein.

P10909	CLUS_HUMAN	Clusterin	16548883	Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection.

P40235	HHP1_SCHPO	Casein kinase I homolog hhp1	8026462	Characterization of two protein kinases from Schizosaccharomyces pombe involved in the regulation of DNA repair.

P36080	RRP14_YEAST	Ribosomal RNA-processing protein 14	17804645	Yeast Rrp14p is a nucleolar protein involved in both ribosome biogenesis and cell polarity.

Q12098	SLX4_YEAST	Structure-specific endonuclease subunit SLX4	11139495	Requirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiae.

Q01887	RYK_MOUSE	Tyrosine-protein kinase RYK	7822791	The receptor tyrosine kinase-related gene (ryk) demonstrates lineage and stage-specific expression in hematopoietic cells.

Q03330	GCN5_YEAST	Histone acetyltransferase GCN5	10490601	The ADA complex is a distinct histone acetyltransferase complex in Saccharomyces cerevisiae.

P38221	CDS1_YEAST	Phosphatidate cytidylyltransferase	8557688	The CDS1 gene encoding CDP-diacylglycerol synthase in Saccharomyces cerevisiae is essential for cell growth.

P19882	HSP60_YEAST	Heat shock protein 60, mitochondrial	11502169	Yeast mitochondrial dehydrogenases are associated in a supramolecular complex.

Q02083	NAAA_HUMAN	N-acylethanolamine-hydrolyzing acid amidase	10610717	Molecular cloning and characterization of a human cDNA and gene encoding a novel acid ceramidase-like protein.

Q92988	DLX4_HUMAN	Homeobox protein DLX-4	9073066	Isolation and identification of homeobox genes from the human placenta including a novel member of the Distal-less family, DLX4.

P16109	LYAM3_HUMAN	P-selectin	2466574	Cloning of GMP-140, a granule membrane protein of platelets and endothelium: sequence similarity to proteins involved in cell adhesion and inflammation.

Q96BY2	MOAP1_HUMAN	Modulator of apoptosis 1	11060313	MAP-1, a novel proapoptotic protein containing a BH3-like motif that associates with Bax through its Bcl-2 homology domains.

P87297	DAD1_SCHPO	DASH complex subunit dad1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q86VQ0	LCA5_HUMAN	Lebercilin	19800048	OFD1 is mutated in X-linked Joubert syndrome and interacts with LCA5- encoded lebercilin.

Q99ML5	PCYOX_RAT	Prenylcysteine oxidase	11716481	Molecular cloning and characterization of the Cl(-) pump-associated 55-kDa protein in rat brain.

Q54ER9	DIMB_DICDI	Basic-leucine zipper transcription factor B	16410410	bZIP transcription factor interactions regulate DIF responses in Dictyostelium.

Q9C0W2	YHI5_SCHPO	Uncharacterized AAA domain-containing protein P22H7.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q7LFL8	CXXC5_HUMAN	CXXC-type zinc finger protein 5	12761501	Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.

P55011	S12A2_HUMAN	Solute carrier family 12 member 2	7629105	Primary structure, functional expression, and chromosomal localization of the bumetanide-sensitive Na-K-Cl cotransporter in human colon.

Q8STE5	CED12_CAEEL	Cell death abnormality protein 12	15744306	Two pathways converge at CED-10 to mediate actin rearrangement and corpse removal in C. elegans.

Q9P3V9	YI41_SCHPO	UPF0494 membrane protein C1348.01/CPT2R1.01c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P11151	LIPL_BOVIN	Lipoprotein lipase	10727238	Apolipoprotein C-II39-62 activates lipoprotein lipase by direct lipid-independent binding.

Q811S9	GNL3_RAT	Guanine nucleotide-binding protein-like 3	15657390	A multistep, GTP-driven mechanism controlling the dynamic cycling of nucleostemin.

B7ZR65	SOX9A_XENLA	Transcription factor Sox-9-A	11807034	The transcription factor Sox9 is required for cranial neural crest development in Xenopus.

Q04228	UBX2_YEAST	UBX domain-containing protein 2	16873066	Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins.

P40427	EXD_DROME	Homeobox protein extradenticle	9450936	The Homothorax homeoprotein activates the nuclear localization of another homeoprotein, extradenticle, and suppresses eye development in Drosophila.

P37285	KLC1_RAT	Kinesin light chain 1	1946431	Molecular genetics of kinesin light chains: generation of isoforms by alternative splicing.

P26718	NKG2D_HUMAN	NKG2-D type II integral membrane protein	2007850	DNA sequence analysis of NKG2, a family of related cDNA clones encoding type II integral membrane proteins on human natural killer cells.

O75506	HSBP1_HUMAN	Heat shock factor-binding protein 1	9649501	Negative regulation of the heat shock transcriptional response by HSBP1.

Q9P7I9	EMP24_SCHPO	Endosomal protein P24B	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P16310	GHR_RAT	Growth hormone receptor	2722883	Regulation of rat growth hormone receptor gene expression.

Q13416	ORC2_HUMAN	Origin recognition complex subunit 2	11095689	The human homolog of Saccharomyces cerevisiae Mcm10 interacts with replication factors and dissociates from nuclease-resistant nuclear structures in G(2) phase.

A5HAK0	RNSL3_DANRE	Ribonuclease-like 3	17347156	Zebrafish ribonucleases are bactericidal: implications for the origin of the vertebrate RNase A superfamily.

P51816	AFF2_HUMAN	AF4/FMR2 family member 2	8673086	Identification of FMR2, a novel gene associated with the FRAXE CCG repeat and CpG island.

P0C093	SLMA_ECOLI	HTH-type protein slmA	15916962	SlmA, a nucleoid-associated, ftsZ binding protein required for blocking septal ring assembly over chromosomes in E. coli.

P41350	CAV1_RAT	Caveolin-1	11883949	ATP dependence of the SNARE/caveolin 1 interaction in the hippocampus.

P53063	DOM3Z_YEAST	RAT1-interacting protein	12612077	Intersection of the Kap123p-mediated nuclear import and ribosome export pathways.

P16621	LAR_DROME	Tyrosine-protein phosphatase Lar	2554325	A family of receptor-linked protein tyrosine phosphatases in humans and Drosophila.

Q12050	ELG1_YEAST	Telomere length regulation protein ELG1	12909721	ELG1, a yeast gene required for genome stability, forms a complex related to replication factor C.

Q9P358	PGLRA_ASPAW	Endopolygalacturonase A	10945248	Purification and characterization of acid-stable protopectinase produced by Aspergillus awamori in solid-state fermentation.

P63159	HMGB1_RAT	High mobility group protein B1	1885601	30-kDa heparin-binding protein of brain (amphoterin) involved in neurite outgrowth. Amino acid sequence and localization in the filopodia of the advancing plasma membrane.

P56211	ARP19_HUMAN	cAMP-regulated phosphoprotein 19	9653196	Human alpha-endosulfine, a possible regulator of sulfonylurea- sensitive K(ATP) channel: molecular cloning, expression and biological properties.

Q9UTL7	GPN2_SCHPO	GPN-loop GTPase 2 homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q99380	OST4_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST4	8621712	The OST4 gene of Saccharomyces cerevisiae encodes an unusually small protein required for normal levels of oligosaccharyltransferase activity.

O81077	ABAH2_ARATH	Abscisic acid 8'-hydroxylase 2	17010113	Regulation of hormone metabolism in Arabidopsis seeds: phytochrome regulation of abscisic acid metabolism and abscisic acid regulation of gibberellin metabolism.

P49817	CAV1_MOUSE	Caveolin-1	10631317	Caveolin-1 isoforms are encoded in distinct mRNAs: identification of mouse caveolin-1 mRNA variants caused by alternative transcription initiation and splicing.

Q9Z220	TSG10_RAT	Testis-specific gene 10 protein	14585816	Tsga10 encodes a 65-kilodalton protein that is processed to the 27- kilodalton fibrous sheath protein.

Q9Z185	PADI1_MOUSE	Protein-arginine deiminase type-1	10092850	Molecular cloning of cDNAs of mouse peptidylarginine deiminase type I, type III and type IV, and the expression pattern of type I in mouse.

Q9Y233	PDE10_HUMAN	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	10373451	Cloning and characterization of a novel human phosphodiesterase that hydrolyzes both cAMP and cGMP (PDE10A).

Q9V535	RBM8A_DROME	RNA-binding protein 8A	11691839	The RNA-binding protein Tsunagi interacts with Mago Nashi to establish polarity and localize oskar mRNA during Drosophila oogenesis.

P20849	CO9A1_HUMAN	Collagen alpha-1(IX) chain	8660302	Collagen type IX from human cartilage: a structural profile of intermolecular cross-linking sites.

Q13162	PRDX4_HUMAN	Peroxiredoxin-4	9388242	Regulatory role for a novel human thioredoxin peroxidase in NF-kappaB activation.

Q9Y2K2	SIK3_HUMAN	Serine/threonine-protein kinase SIK3	14976552	LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1.

Q14160	SCRIB_HUMAN	Protein scribble homolog	19041750	Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma.

Q5D7H4	HUGAB_VESVU	Hyaluronidase B	16218950	The N-glycans of yellow jacket venom hyaluronidases and the protein sequence of its major isoform in Vespula vulgaris.

Q9D2L5	CPXM2_MOUSE	Inactive carboxypeptidase-like protein X2	9809751	Identification of mouse CPX-2, a novel member of the metallocarboxypeptidase gene family: cDNA cloning, mRNA distribution, and protein expression and characterization.

Q9Z0F5	CH25H_MOUSE	Cholesterol 25-hydroxylase	9852097	cDNA cloning of mouse and human cholesterol 25-hydroxylases, polytopic membrane proteins that synthesize a potent oxysterol regulator of lipid metabolism.

P01060	IBB2_PHAVU	Bowman-Birk type proteinase inhibitor 2	4684708	Isolation of three isoinhibitors of trypsin from garden bean, Phaseolus vulgaris, having either lysine or arginine at the reactive site.

Q8WY64	MYLIP_HUMAN	E3 ubiquitin-protein ligase MYLIP	10593918	MIR is a novel ERM-like protein that interacts with myosin regulatory light chain and inhibits neurite outgrowth.

Q02153	GCYB1_HUMAN	Guanylate cyclase soluble subunit beta-1	1352257	Molecular cloning of the cDNAs coding for the two subunits of soluble guanylyl cyclase from human brain.

Q14790	CASP8_HUMAN	Caspase-8	10442631	PED/PEA-15: an anti-apoptotic molecule that regulates FAS/TNFR1- induced apoptosis.

Q9SWG3	FAR1_ARATH	Protein FAR-RED IMPAIRED RESPONSE 1	10444599	The FAR1 locus encodes a novel nuclear protein specific to phytochrome A signaling.

P16892	FUS3_YEAST	Mitogen-activated protein kinase FUS3	11781566	MAP kinase dynamics in response to pheromones in budding yeast.

P46581	NDF1_CAEEL	Neurogenic differentiation factor 1	10976055	The C. elegans NeuroD homolog cnd-1 functions in multiple aspects of motor neuron fate specification.

P05783	K1C18_HUMAN	Keratin, type I cytoskeletal 18	15529338	Global proteomic approach unmasks involvement of keratins 8 and 18 in the delivery of cystic fibrosis transmembrane conductance regulator (CFTR)/deltaF508-CFTR to the plasma membrane.

P87041	GMS1_SCHPO	UDP-galactose transporter	9125114	The Schizosaccharomyces pombe gms1+ gene encodes an UDP-galactose transporter homologue required for protein galactosylation.

P40354	NTA1_YEAST	Protein N-terminal amidase	7744855	Yeast N-terminal amidase. A new enzyme and component of the N-end rule pathway.

Q9WU67	LY6I_MOUSE	Lymphocyte antigen 6I	10807778	Characterization of Ly-6M, a novel member of the Ly-6 family of hematopoietic proteins.

Q06102	YTH1_YEAST	mRNA 3'-end-processing protein YTH1	10899131	Distinct roles of two Yth1p domains in 3'-end cleavage and polyadenylation of yeast pre-mRNAs.

Q96320	HSFB1_ARATH	Heat stress transcription factor B-1	9645433	HSF3, a new heat shock factor from Arabidopsis thaliana, derepresses the heat shock response and confers thermotolerance when overexpressed in transgenic plants.

O22769	NDUV2_ARATH	NADH-ubiquinone oxidoreductase 24 kDa subunit, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q5RLM2	S22A7_RAT	Solute carrier family 22 member 7	8056831	Molecular cloning and characterization of a novel liver-specific transport protein.

Q9USK5	TIP41_SCHPO	Type 2A phosphatase activator tip41	16297994	Fission yeast homologue of Tip41-like proteins regulates type 2A phosphatases and responses to nitrogen sources.

P16671	CD36_HUMAN	Platelet glycoprotein 4	2468669	Isolation and characterization of platelet glycoprotein IV (CD36).

Q9YHY9	OTC_CHICK	Ornithine carbamoyltransferase, mitochondrial	6418730	Chicken ornithine transcarbamylase: purification and some properties.

O35082	KLOT_MOUSE	Klotho	11095966	Disruption of klotho gene causes an abnormal energy homeostasis in mice.

Q9SE43	REV_ARATH	Homeobox-leucine zipper protein REVOLUTA	10559440	IFL1, a gene regulating interfascicular fiber differentiation in Arabidopsis, encodes a homeodomain-leucine zipper protein.

Q9FF86	DCR_ARATH	BAHD acyltransferase DCR	19626137	Transcriptome analysis of Arabidopsis wild-type and gl3-sst sim trichomes identifies four additional genes required for trichome development.

P22063	CNTN2_RAT	Contactin-2	2317872	The axonal glycoprotein TAG-1 is an immunoglobulin superfamily member with neurite outgrowth-promoting activity.

Q15013	MD2BP_HUMAN	MAD2L1-binding protein	18022368	p31comet blocks Mad2 activation through structural mimicry.

O80562	HOL2_ARATH	Probable thiol methyltransferase 1	19419967	Arabidopsis HARMLESS TO OZONE LAYER protein methylates a glucosinolate breakdown product and functions in resistance to Pseudomonas syringae pv. maculicola.

P52429	DGKE_HUMAN	Diacylglycerol kinase epsilon	8626589	Molecular cloning of a novel human diacylglycerol kinase highly selective for arachidonate-containing substrates.

P93022	ARFG_ARATH	Auxin response factor 7	9342315	Protein-protein interactions among the Aux/IAA proteins.

Q9VDZ3	SQZ_DROME	Zinc finger protein squeeze	17276922	Intrinsic control of precise dendritic targeting by an ensemble of transcription factors.

P24594	IBP5_RAT	Insulin-like growth factor-binding protein 5	1709938	Identification of five different insulin-like growth factor binding proteins (IGFBPs) from adult rat serum and molecular cloning of a novel IGFBP-5 in rat and human.

Q54B59	OMT12_DICDI	O-methyltransferase 12	18252726	Dissecting the functional role of polyketide synthases in Dictyostelium discoideum: biosynthesis of the differentiation regulating factor 4-methyl-5-pentylbenzene-1,3-diol.

Q02908	ELP3_YEAST	Elongator complex protein 3	11689709	Characterization of a six-subunit holo-elongator complex required for the regulated expression of a group of genes in Saccharomyces cerevisiae.

P10826	RARB_HUMAN	Retinoic acid receptor beta	2833708	Identification of a second human retinoic acid receptor.

Q92186	SIA8B_HUMAN	Alpha-2,8-sialyltransferase 8B	7559389	A human STX cDNA confers polysialic acid expression in mammalian cells.

O88898	P63_MOUSE	Tumor protein 63	14729569	p63 is the molecular switch for initiation of an epithelial stratification program.

P13864	DNMT1_MOUSE	DNA (cytosine-5)-methyltransferase 1	10888872	DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci.

Q12465	RAX2_YEAST	Bud site selection protein RAX2	11110666	Multigenerational cortical inheritance of the Rax2 protein in orienting polarity and division in yeast.

P16066	ANPRA_HUMAN	Atrial natriuretic peptide receptor 1	1660465	Extracellular domain-IgG fusion proteins for three human natriuretic peptide receptors. Hormone pharmacology and application to solid phase screening of synthetic peptide antisera.

Q05610	DON1_YEAST	Donuts protein 1	10899120	Role of the spindle pole body of yeast in mediating assembly of the prospore membrane during meiosis.

P38909	CYC2_YEAST	Cytochrome c mitochondrial import factor CYC2	16207709	Cyc2p, a membrane-bound flavoprotein involved in the maturation of mitochondrial c-type cytochromes.

Q08179	MDM38_YEAST	Mitochondrial distribution and morphology protein 38	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q1EHW4	SAP25_MOUSE	Histone deacetylase complex subunit SAP25	16449650	Identification and characterization of SAP25, a novel component of the mSin3 corepressor complex.

P26019	DPOLA_DROME	DNA polymerase alpha catalytic subunit	1429896	Molecular characterisation of the gene for the 180 kDa subunit of the DNA polymerase-primase of Drosophila melanogaster.

O74921	YJ7B_SCHPO	Uncharacterized MFS-type transporter C757.11c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O94480	YC6D_SCHPO	UPF0617 protein C1919.13c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12186	BBP_YEAST	Branchpoint-bridging protein	16120600	GYF domain proteomics reveals interaction sites in known and novel target proteins.

Q7KTH8	CSN8_DROME	COP9 signalosome complex subunit 8	18298797	Cop9 signalosome subunit 8 (CSN8) is essential for Drosophila development.

Q92968	PEX13_HUMAN	Peroxisomal membrane protein PEX13	8858165	Pex13p is an SH3 protein of the peroxisome membrane and a docking factor for the predominantly cytoplasmic PTs1 receptor.

Q8IRY7	CASP8_DROME	Caspase-8	9740659	Dredd, a novel effector of the apoptosis activators reaper, grim, and hid in Drosophila.

P28496	LAC1_YEAST	Sphingosine N-acyltransferase LAC1	11694577	Lag1p and Lac1p are essential for the acyl-CoA-dependent ceramide synthase reaction in Saccharomyces cerevisae.

Q55AR6	NFAA_DICDI	Neurofibromin-A	18948008	Spatiotemporal regulation of Ras activity provides directional sensing.

Q9VLJ0	PDE6D_DROME	Probable cGMP 3',5'-cyclic phosphodiesterase subunit delta	18503409	Regulation of a Drosophila melanogaster cGMP-specific phosphodiesterase by prenylation and interaction with a prenyl-binding protein.

P36062	AVT3_YEAST	Vacuolar amino acid transporter 3	11274162	A family of yeast proteins mediating bidirectional vacuolar amino acid transport.

Q96KG9	NTKL_HUMAN	N-terminal kinase-like protein	10843802	Construction of a 350-kb sequence-ready 11q13 cosmid contig encompassing the markers D11S4933 and D11S546: mapping of 11 genes and 3 tumor-associated translocation breakpoints.

Q91V45	KISSR_MOUSE	KiSS-1 receptor	11414709	FMRFamide-related neuropeptides are agonists of the orphan G-protein- coupled receptor GPR54.

Q9XFH8	TRXF1_ARATH	Thioredoxin F1, chloroplastic	19631646	Redox regulation of chloroplastic glucose-6-phosphate dehydrogenase: a new role for f-type thioredoxin.

Q09293	MEL47_CAEEL	Maternal effect lethal protein 47	17171368	MEL-47, a novel protein required for early cell divisions in the nematode Caenorhabditis elegans.

P05696	KPCA_RAT	Protein kinase C alpha type	9566962	Targeting of protein kinase Calpha to caveolae.

Q9VHR8	DPP3_DROME	Dipeptidyl peptidase 3	12846841	Characterization of a functionally expressed dipeptidyl aminopeptidase III from Drosophila melanogaster.

O14122	CUL4_SCHPO	Cullin-4	16157682	The Clr7 and Clr8 directionality factors and the Pcu4 cullin mediate heterochromatin formation in the fission yeast Schizosaccharomyces pombe.

P18433	PTPRA_HUMAN	Receptor-type tyrosine-protein phosphatase alpha	2169617	Cloning of three human tyrosine phosphatases reveals a multigene family of receptor-linked protein-tyrosine-phosphatases expressed in brain.

P42212	GFP_AEQVI	Green fluorescent protein	8137953	Aequorea green fluorescent protein. Expression of the gene and fluorescence characteristics of the recombinant protein.

P40903	ISP6_SCHPO	Sexual differentiation process putative subtilase-type proteinase isp6	7954893	Identification and characterization of genes induced during sexual differentiation in Schizosaccharomyces pombe.

Q13427	PPIG_HUMAN	Peptidyl-prolyl cis-trans isomerase G	9153302	A serine/arginine-rich nuclear matrix cyclophilin interacts with the C-terminal domain of RNA polymerase II.

P32367	TFC1_YEAST	Transcription factor tau 95 kDa subunit	2180956	Purification and characterization of Saccharomyces cerevisiae transcription factor TFIIIC. Polypeptide composition defined with polyclonal antibodies.

Q9WV86	KTNA1_MOUSE	Katanin p60 ATPase-containing subunit A1	10445032	Lipotransin: a novel docking protein for hormone-sensitive lipase.

Q64373	B2CL1_MOUSE	Bcl-2-like protein 1	7607090	bcl-XL is the major bcl-x mRNA form expressed during murine development and its product localizes to mitochondria.

Q91WG8	GLCNE_MOUSE	Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase	10103025	Tissue expression and amino acid sequence of murine UDP-N- acetylglucosamine-2-epimerase/N-acetylmannosamine kinase.

Q64324	STXB2_MOUSE	Syntaxin-binding protein 2	7890599	A novel isoform of syntaxin-binding protein homologous to yeast Sec1 expressed ubiquitously in mammalian cells.

P11076	ARF1_YEAST	ADP-ribosylation factor 1	15504911	The GTPase Arf1p and the ER to Golgi cargo receptor Erv14p cooperate to recruit the golgin Rud3p to the cis-Golgi.

Q9CA86	PEX2_ARATH	Peroxisome assembly protein 2	12130786	A role for peroxisomes in photomorphogenesis and development of Arabidopsis.

O59800	SLT11_SCHPO	Pre-mRNA-splicing factor slt11	11884590	Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

P54679	PMA1_DICDI	Probable plasma membrane ATPase	9421912	The patB gene of Dictyostelium discoideum encodes a P-type H(+)- ATPase isoform essential for growth and development under acidic conditions.

Q96VG0	YH7J_SCHPO	Uncharacterized protein C16G5.19	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P23416	GLRA2_HUMAN	Glycine receptor subunit alpha-2	2155780	Alpha subunit variants of the human glycine receptor: primary structures, functional expression and chromosomal localization of the corresponding genes.

Q76EI6	FFAR2_RAT	Free fatty acid receptor 2	16453106	Short-chain fatty acid receptor, GPR43, is expressed by enteroendocrine cells and mucosal mast cells in rat intestine.

Q12369	SFI1_YEAST	Protein SFI1	14504268	Sfi1p has conserved centrin-binding sites and an essential function in budding yeast spindle pole body duplication.

Q7PMG3	GR22_ANOGA	Gustatory and odorant receptor 22	17167414	Two chemosensory receptors together mediate carbon dioxide detection in Drosophila.

O96018	APBA3_HUMAN	Amyloid beta A4 precursor protein-binding family A member 3	10049767	X11L2, a new member of X11 protein family interacts with Alzheimer's beta-amyloid precursor protein.

Q63538	MK12_RAT	Mitogen-activated protein kinase 12	11991731	Cardiac expression and subcellular localization of the p38 mitogen- activated protein kinase member, stress-activated protein kinase-3 (SAPK3).

Q96PM5	ZN363_HUMAN	RING finger and CHY zinc finger domain-containing protein 1	19483087	Identification and characterization of two novel isoforms of Pirh2 ubiquitin ligase that negatively regulate p53 independent of RING finger domains.

Q64249	NR6A1_MOUSE	Nuclear receptor subfamily 6 group A member 1	12080054	RAP80: a novel nuclear protein that interacts with the retinoid- related testis-associated receptor.

O54839	EOMES_MOUSE	Eomesodermin homolog	18940588	Tbr2 directs conversion of radial glia into basal precursors and guides neuronal amplification by indirect neurogenesis in the developing neocortex.

P10635	CP2D6_HUMAN	Cytochrome P450 2D6	16352597	Crystal structure of human cytochrome P450 2D6.

Q06417	YL426_YEAST	Uncharacterized oxidoreductase YLR426W	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q12450	ERP4_YEAST	Protein ERP4	10359606	Erp1p and Erp2p, partners for Emp24p and Erv25p in a yeast p24 complex.

Q9W534	MOODY_DROME	G-protein coupled receptor moody	16213218	GPCR signaling is required for blood-brain barrier formation in Drosophila.

Q9GYV9	MED7_DROME	Mediator of RNA polymerase II transcription subunit 7	15477388	A high resolution protein interaction map of the yeast Mediator complex.

Q52K88	NUD13_ARATH	Nudix hydrolase 13, mitochondrial	17824959	Cloning and characterization of AtNUDT13, a novel mitochondrial Arabidopsis thaliana Nudix hydrolase specific for long-chain diadenosine polyphosphates.

P11511	CP19A_HUMAN	Cytochrome P450 19A1	1371509	Biochemical and molecular genetic analyses on placental aromatase (P- 450AROM) deficiency.

P15425	CYPR_DROME	Peptidyl-prolyl cis-trans isomerase, rhodopsin-specific isozyme	2493138	The ninaA gene required for visual transduction in Drosophila encodes a homologue of cyclosporin A-binding protein.

O54861	SORT_RAT	Sortilin	12746864	Distribution of NTS3 receptor/sortilin mRNA and protein in the rat central nervous system.

P38398	BRCA1_HUMAN	Breast cancer type 1 susceptibility protein	11739404	BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations.

P53311	FMP43_YEAST	UPF0041 protein FMP43	14562095	Global analysis of protein localization in budding yeast.

Q70KF4	CMYA5_MOUSE	Cardiomyopathy-associated protein 5	14688250	Myospryn is a novel binding partner for dysbindin in muscle.

Q6UWV6	ENPP7_HUMAN	Ectonucleotide pyrophosphatase/phosphodiesterase family member 7	12885774	Identification of human intestinal alkaline sphingomyelinase as a novel ecto-enzyme related to the nucleotide phosphodiesterase family.

P68181	KAPCB_MOUSE	cAMP-dependent protein kinase catalytic subunit beta	9368018	Two novel brain-specific splice variants of the murine Cbeta gene of cAMP-dependent protein kinase.

Q9S744	CML9_ARATH	Calmodulin-like protein 9	11855649	Characterization of three new members of the Arabidopsis thaliana calmodulin gene family: conserved and highly diverged members of the gene family functionally complement a yeast calmodulin null.

P41566	IDH3G_PIG	Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial	2605193	Cysteinyl peptide labeled by 3-bromo-2-ketoglutarate in the active site of pig heart NAD+-dependent isocitrate dehydrogenase.

Q20646	CEP1_CAEEL	Transcription factor cep-1	18836529	A novel role for the SMG-1 kinase in lifespan and oxidative stress resistance in Caenorhabditis elegans.

Q9P202	WHRN_HUMAN	Whirlin	17584769	MPP1 links the Usher protein network and the Crumbs protein complex in the retina.

P13725	ONCM_HUMAN	Oncostatin-M	1717982	Oncostatin M is a member of a cytokine family that includes leukemia- inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6.

P21965	MCK1_YEAST	Protein kinase MCK1	2010083	The yeast MCK1 gene encodes a protein kinase homolog that activates early meiotic gene expression.

Q8IVF5	TIAM2_HUMAN	T-lymphoma invasion and metastasis-inducing protein 2	10512681	Cloning and characterization of T-cell lymphoma invasion and metastasis 2 (TIAM2), a novel guanine nucleotide exchange factor related to TIAM1.

P63282	UBC9_XENLA	SUMO-conjugating enzyme UBC9	16256735	SoxE factors function equivalently during neural crest and inner ear development and their activity is regulated by SUMOylation.

O13900	SA114_SCHPO	Pre-mRNA-splicing factor sap114	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8TAT6	NPL4_HUMAN	Nuclear protein localization protein 4 homolog	11574150	Cloning and characterization of the gene encoding human NPL4, a protein interacting with the ubiquitin fusion-degradation protein (UFD1L).

O14880	MGST3_HUMAN	Microsomal glutathione S-transferase 3	9278457	Identification and characterization of a novel microsomal enzyme with glutathione-dependent transferase and peroxidase activities.

O59706	SAP61_SCHPO	CWF complex protein sap61	11884590	Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

O64948	LONP2_ARATH	Lon protease homolog 2, peroxisomal	19748917	Arabidopsis LON2 is necessary for peroxisomal function and sustained matrix protein import.

P31695	NOTC4_MOUSE	Neurogenic locus notch homolog protein 4	11344305	Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium.

P40855	PEX19_HUMAN	Peroxisomal biogenesis factor 19	19197237	Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19.

Q8CG08	CTHR1_RAT	Collagen triple helix repeat-containing protein 1	15618538	Collagen triple helix repeat containing 1, a novel secreted protein in injured and diseased arteries, inhibits collagen expression and promotes cell migration.

Q08032	CDC45_YEAST	Cell division control protein 45	8901577	Cdc45p assembles into a complex with Cdc46p/Mcm5p, is required for minichromosome maintenance, and is essential for chromosomal DNA replication.

Q07953	SDO1_YEAST	Ribosome maturation protein SDO1	15701634	The Shwachman-Bodian-Diamond syndrome protein family is involved in RNA metabolism.

Q12432	EAF3_YEAST	Chromatin modification-related protein EAF3	11036083	The yeast NuA4 and Drosophila MSL complexes contain homologous subunits important for transcriptional regulation.

Q64640	ADK_RAT	Adenosine kinase	8917457	Cloning and characterization of cDNA for adenosine kinase from mammalian (Chinese hamster, mouse, human and rat) species. High frequency mutants of Chinese hamster ovary cells involve structural alterations in the gene.

Q53HL2	BOREA_HUMAN	Borealin	15260989	The chromosomal passenger complex is required for chromatin-induced microtubule stabilization and spindle assembly.

Q02223	TNR17_HUMAN	Tumor necrosis factor receptor superfamily member 17	10801128	TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease.

P54681	RTOA_DICDI	Protein rtoA	8951083	RtoA links initial cell type choice to the cell cycle in Dictyostelium.

Q9W1C9	PEB3_DROME	Ejaculatory bulb-specific protein 3	7619487	Method for attachment of microscopic preparations on glass for in situ hybridization, PRINS and in situ PCR studies.

A8MPH9	FOSLD_DROME	Transcription factor kayak, isoforms D/sro	2116361	The Drosophila Fos-related AP-1 protein is a developmentally regulated transcription factor.

Q12309	CLF1_YEAST	Pre-mRNA-splicing factor CLF1	10445879	Yeast ortholog of the Drosophila crooked neck protein promotes spliceosome assembly through stable U4/U6.U5 snRNP addition.

Q9FLN0	GLIP1_ARATH	GDSL esterase/lipase 1	16126835	Secretome analysis reveals an Arabidopsis lipase involved in defense against Alternaria brassicicola.

P67775	PP2AA_HUMAN	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform	17485487	Tripin/hSgo2 recruits MCAK to the inner centromere to correct defective kinetochore attachments.

P98149	DIF_DROME	Dorsal-related immunity factor Dif	8242747	Dif, a dorsal-related gene that mediates an immune response in Drosophila.

Q9NP72	RAB18_HUMAN	Ras-related protein Rab-18	10648831	Isolation and characterisation of the human rab18 gene after stimulation of endothelial cells with histamine.

Q9Z1B5	MD2L1_MOUSE	Mitotic spindle assembly checkpoint protein MAD2A	10892650	Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2.

Q8WPJ2	MANA_MYTED	Mannan endo-1,4-beta-mannosidase	11689251	endo-beta-1,4-mannanases from blue mussel, Mytilus edulis: purification, characterization, and mode of action.

P91926	AP2A_DROME	AP-2 complex subunit alpha	9118220	Role of Drosophila alpha-adaptin in presynaptic vesicle recycling.

P52489	KPYK2_YEAST	Pyruvate kinase 2	9139918	Characterization of a glucose-repressed pyruvate kinase (Pyk2p) in Saccharomyces cerevisiae that is catalytically insensitive to fructose-1,6-bisphosphate.

Q9JJ72	RPRM_MOUSE	Protein reprimo	10930422	Reprimo, a new candidate mediator of the p53-mediated cell cycle arrest at the G2 phase.

Q9C0E2	XPO4_HUMAN	Exportin-4	10944119	Exportin 4: a mediator of a novel nuclear export pathway in higher eukaryotes.

Q6PFM0	JMJD6_DANRE	Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6	15469976	Phosphatidylserine receptor is required for the engulfment of dead apoptotic cells and for normal embryonic development in zebrafish.

Q9LL45	TBP1_ORYSJ	Telomere-binding protein 1	10811811	Sequence-specific DNA recognition by the Myb-like domain of plant telomeric protein RTBP1.

P70552	GFRP_RAT	GTP cyclohydrolase 1 feedback regulatory protein	11818540	Crystal structure of the stimulatory complex of GTP cyclohydrolase I and its feedback regulatory protein GFRP.

Q9FYE2	PKS4_ARATH	Protein PHYTOCHROME KINASE SUBSTRATE 4	16777956	PHYTOCHROME KINASE SUBSTRATE 1 is a phototropin 1 binding protein required for phototropism.

Q9UT23	MFH1_SCHPO	ATP-dependent DNA helicase mfh1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O95393	BMP10_HUMAN	Bone morphogenetic protein 10	17068149	Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells.

Q9VXY7	LSD2_DROME	Lipid storage droplets surface-binding protein 2	12676093	Control of fat storage by a Drosophila PAT domain protein.

Q9UNE7	CHIP_HUMAN	E3 ubiquitin-protein ligase CHIP	11146632	The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins.

Q14392	LRC32_HUMAN	Leucine-rich repeat-containing protein 32	8180135	The GARP gene encodes a new member of the family of leucine-rich repeat-containing proteins.

O14613	BORG1_HUMAN	Cdc42 effector protein 2	11584266	Borg proteins control septin organization and are negatively regulated by Cdc42.

P31994	FCG2B_HUMAN	Low affinity immunoglobulin gamma Fc region receptor II-b	2142460	Distribution, inducibility and biological function of the cloned and expressed human beta Fc receptor II.

Q9UMX1	SUFU_HUMAN	Suppressor of fused homolog	10559945	Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1.

Q9BY41	HDAC8_HUMAN	Histone deacetylase 8	10748112	Cloning and characterization of a novel human class I histone deacetylase that functions as a transcription repressor.

Q12318	PSY3_YEAST	Platinum sensitivity protein 3	15654096	A genetic screen for top3 suppressors in Saccharomyces cerevisiae identifies SHU1, SHU2, PSY3 and CSM2: four genes involved in error- free DNA repair.

P32447	ASF1_YEAST	Histone chaperone ASF1	11412995	Yeast histone deposition protein Asf1p requires Hir proteins and PCNA for heterochromatic silencing.

P63316	TNNC1_HUMAN	Troponin C, slow skeletal and cardiac muscles	2250022	Cloning, structural analysis, and expression of the human slow twitch skeletal muscle/cardiac troponin C gene.

O75751	S22A3_HUMAN	Solute carrier family 22 member 3	9933568	Cloning of the mouse and human solute carrier 22a3 (Slc22a3/SLC22A3) identifies a conserved cluster of three organic cation transporters on mouse chromosome 17 and human 6q26-q27.

Q54RP0	AGTA_DICDI	UDP-galactose:fucoside alpha-3-galactosyltransferase	16495217	Molecular characterization of a novel UDP-galactose:fucoside alpha3- galactosyltransferase that modifies Skp1 in the cytoplasm of Dictyostelium.

Q9P031	TAP26_HUMAN	Thyroid transcription factor 1-associated protein 26	11152647	BR22, a novel protein, interacts with thyroid transcription factor-1 and activates the human surfactant protein B promoter.

Q05611	BSC2_YEAST	Bypass of stop codon protein 2	14562095	Global analysis of protein localization in budding yeast.

Q27913	GBP_PSESE	Growth-blocking peptide, long form	9753606	Cell growth activity of growth-blocking peptide.

P55034	PSMD4_ARATH	26S proteasome non-ATPase regulatory subunit 4	9442033	Multiubiquitin chain binding and protein degradation are mediated by distinct domains within the 26 S proteasome subunit Mcb1.

O95976	IGSF6_HUMAN	Immunoglobulin superfamily member 6	9809579	CD40L activation of dendritic cells down-regulates DORA, a novel member of the immunoglobulin superfamily.

O43903	GAS2_HUMAN	Growth arrest-specific protein 2	9521882	cDNA characterization and chromosome mapping of the human GAS2 gene.

P35845	OSH1_YEAST	Oxysterol-binding protein homolog 1	12727870	A conserved ER targeting motif in three families of lipid binding proteins and in Opi1p binds VAP.

Q12034	SLF1_YEAST	Protein SLF1	8628314	Identification of SLF1 as a new copper homeostasis gene involved in copper sulfide mineralization in Saccharomyces cerevisiae.

O35760	IDI1_RAT	Isopentenyl-diphosphate Delta-isomerase 1	9228075	Cloning and subcellular localization of hamster and rat isopentenyl diphosphate dimethylallyl diphosphate isomerase. A PTS1 motif targets the enzyme to peroxisomes.

P38346	BIT2_YEAST	Probable target of rapamycin complex 2 subunit BIT2	11283351	A comprehensive two-hybrid analysis to explore the yeast protein interactome.

Q9UBF6	RBX2_HUMAN	RING-box protein 2	19250909	E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification.

P32522	PT309_YEAST	Pentatricopeptide repeat-containing protein PET309, mitochondrial	7664742	The product of the nuclear gene PET309 is required for translation of mature mRNA and stability or production of intron-containing RNAs derived from the mitochondrial COX1 locus of Saccharomyces cerevisiae.

O75151	PHF2_HUMAN	PHD finger protein 2	10051327	PHF2, a novel PHD finger gene located on human chromosome 9q22.

Q8TFH5	YIK9_SCHPO	Meiotically up-regulated protein PB17E12.09	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P82869	CYP37_ARATH	Peptidyl-prolyl cis-trans isomerase CYP37, chloroplastic	14729914	In-depth analysis of the thylakoid membrane proteome of Arabidopsis thaliana chloroplasts: new proteins, new functions, and a plastid proteome database.

Q9FGM0	FTSHB_ARATH	ATP-dependent zinc metalloprotease FTSH 11, chloroplastic/mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q22795	SET1_CAEEL	Probable histone-lysine N-methyltransferase set-1	12119097	Characterisation of set-1, a conserved PR/SET domain gene in Caenorhabditis elegans.

Q9C0H9	SRCN1_HUMAN	SRC kinase signaling inhibitor 1	14657239	p130Cas-associated protein (p140Cap) as a new tyrosine-phosphorylated protein involved in cell spreading.

Q99JR6	NMNA3_MOUSE	Nicotinamide mononucleotide adenylyltransferase 3	16914673	Stimulation of nicotinamide adenine dinucleotide biosynthetic pathways delays axonal degeneration after axotomy.

P86166	VPL9A_POLAB	Venom protein Pal9a	18948154	Peptide pal9a from the venom of the turrid snail Polystira albida from the Gulf of Mexico: purification, characterization, and comparison with P-conotoxin-like (framework IX) conoidean peptides.

P70668	GUC2B_RAT	Guanylate cyclase activator 2B	9094754	Purification, cDNA sequence, and tissue distribution of rat uroguanylin.

P83547	CHY3_PAGMA	Chrysophsin-3	12581207	Purification and characterization of three isoforms of chrysophsin, a novel antimicrobial peptide in the gills of the red sea bream, Chrysophrys major.

O75351	VPS4B_HUMAN	Vacuolar protein sorting-associated protein 4B	17928862	ESCRT-III recognition by VPS4 ATPases.

Q9UDY8	MALT1_HUMAN	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	10523859	A novel gene, MALT1 at 18q21, is involved in t(11;18)(q21;q21) found in low-grade B-cell lymphoma of mucosa-associated lymphoid tissue.

P30793	GCH1_HUMAN	GTP cyclohydrolase 1	8068008	Human GTP cyclohydrolase I: only one out of three cDNA isoforms gives rise to the active enzyme.

Q9R0K8	STC2_RAT	Stanniocalcin-2	10508929	Regulation by 1alpha,25-dihydroxyvitamin D(3) of expression of stanniocalcin messages in the rat kidney and ovary.

P40065	MAM1_YEAST	Monopolin complex subunit MAM1	11163190	Functional genomics identifies monopolin: a kinetochore protein required for segregation of homologs during meiosis I.

P61089	UBE2N_MOUSE	Ubiquitin-conjugating enzyme E2 N	12039045	Roles of mouse UBC13 in DNA postreplication repair and Lys63-linked ubiquitination.

O43823	AKAP8_HUMAN	A-kinase anchor protein 8	9473338	Molecular cloning, chromosomal localization, and cell cycle-dependent subcellular distribution of the A-kinase anchoring protein, AKAP95.

Q9SYX2	SPA1_ARATH	Protein SUPPRESSOR OF PHYA-105 1	15960622	Repression of light signaling by Arabidopsis SPA1 involves post- translational regulation of HFR1 protein accumulation.

Q86HW7	NTF2_DICDI	Nuclear transport factor 2	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

Q03112	EVI1_HUMAN	MDS1 and EVI1 complex locus protein EVI1	19767769	Pbx1 is a downstream target of Evi-1 in hematopoietic stem/progenitors and leukemic cells.

O55225	OTOGL_MOUSE	Otogelin	10655058	Targeted disruption of otog results in deafness and severe imbalance.

P40048	PTP3_YEAST	Tyrosine-protein phosphatase 3	9224718	Differential regulation of FUS3 MAP kinase by tyrosine-specific phosphatases PTP2/PTP3 and dual-specificity phosphatase MSG5 in Saccharomyces cerevisiae.

Q04231	RAD33_YEAST	DNA repair protein RAD33	16595192	Rad33, a new factor involved in nucleotide excision repair in Saccharomyces cerevisiae.

Q9VKJ7	GR32A_DROME	Putative gustatory receptor 32a	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

Q967F4	HMR1_CAEEL	Cadherin-related hmr-1	12847081	The Caenorhabditis elegans p120 catenin homologue, JAC-1, modulates cadherin-catenin function during epidermal morphogenesis.

P33195	GCSP_ECOLI	Glycine dehydrogenase [decarboxylating]	8375392	Cloning and nucleotide sequence of the gcv operon encoding the Escherichia coli glycine-cleavage system.

P0A8R0	RRAA_ECOLI	Regulator of ribonuclease activity A	13678585	RraA. a protein inhibitor of RNase E activity that globally modulates RNA abundance in E. coli.

Q9UBD5	ORC3_HUMAN	Origin recognition complex subunit 3	17525332	ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

O15372	EIF3H_HUMAN	Eukaryotic translation initiation factor 3 subunit H	17322308	Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry.

Q96IY1	NSL1_HUMAN	Kinetochore-associated protein NSL1 homolog	16585270	The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation.

Q99417	MYCBP_HUMAN	C-Myc-binding protein	9797456	AMY-1, a novel C-MYC binding protein that stimulates transcription activity of C-MYC.

Q811Q9	PCY1B_MOUSE	Choline-phosphate cytidylyltransferase B	15143167	Disruption of CCTbeta2 expression leads to gonadal dysfunction.

O94436	TAF14_SCHPO	Transcription initiation factor TFIID subunit 14	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P93203	MFP1_SOLLC	MAR-binding filament-like protein 1	10488241	MAF1, a novel plant protein interacting with matrix attachment region binding protein MFP1, is located at the nuclear envelope.

Q3TB82	PKHF1_MOUSE	Pleckstrin homology domain-containing family F member 1	16188880	The lysosome-associated apoptosis-inducing protein containing the pleckstrin homology (PH) and FYVE domains (LAPF), representative of a novel family of PH and FYVE domain-containing proteins, induces caspase-independent apoptosis via the lysosomal-mitochondrial pathway.

Q6IA17	SIGIR_HUMAN	Single Ig IL-1-related receptor	10346978	Identification and characterization of SIGIRR, a molecule representing a novel subtype of the IL-1R superfamily.

P35359	OPSD_DANRE	Rhodopsin	10349976	Cloning and characterization of six zebrafish photoreceptor opsin cDNAs and immunolocalization of their corresponding proteins.

P23561	STE11_YEAST	Serine/threonine-protein kinase STE11	2276621	STE11 is a protein kinase required for cell-type-specific transcription and signal transduction in yeast.

P54144	AMT11_ARATH	Ammonium transporter 1 member 1	17026539	Additive contribution of AMT1;1 and AMT1;3 to high-affinity ammonium uptake across the plasma membrane of nitrogen-deficient Arabidopsis roots.

P53953	SFB2_YEAST	SED5-binding protein 2	10753972	Evidence for overlapping and distinct functions in protein transport of coat protein Sec24p family members.

P00734	THRB_HUMAN	Prothrombin	2719946	Substitution of valine for glycine-558 in the congenital dysthrombin thrombin Quick II alters primary substrate specificity.

O80992	PYL2_ARATH	Abscisic acid receptor PYL2	19407142	Abscisic acid inhibits type 2C protein phosphatases via the PYR/PYL family of START proteins.

Q9Y2P5	S27A5_HUMAN	Bile acyl-CoA synthetase	10479480	Human liver-specific very-long-chain acyl-coenzyme A synthetase: cDNA cloning and characterization of a second enzymatically active protein.

P70605	KCNN3_RAT	Small conductance calcium-activated potassium channel protein 3	11533126	SK3 is an important component of K(+) channels mediating the afterhyperpolarization in cultured rat SCG neurones.

Q91926	VENT1_XENLA	Homeobox protein vent1	8557046	Antagonizing the Spemann organizer: role of the homeobox gene Xvent- 1.

Q01589	SED1_YEAST	Cell wall protein SED1	9642191	Sed1p is a major cell wall protein of Saccharomyces cerevisiae in the stationary phase and is involved in lytic enzyme resistance.

Q9Y7J9	MCP5_SCHPO	Meiotic coiled-coil protein 5	16585273	Mcp5, a meiotic cell cortex protein, is required for nuclear movement mediated by dynein and microtubules in fission yeast.

O75829	LECT1_HUMAN	Chondromodulin-1	10103018	Molecular cloning of human chondromodulin-I, a cartilage-derived growth modulating factor, and its expression in Chinese hamster ovary cells.

O60506	HNRPQ_HUMAN	Heterogeneous nuclear ribonucleoprotein Q	19029303	Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs.

Q9LDT3	YAB4_ARATH	Axial regulator YABBY 4	12183380	SUPERMAN attenuates positive INNER NO OUTER autoregulation to maintain polar development of Arabidopsis ovule outer integuments.

P48233	CMC1_YEAST	Calcium-binding mitochondrial carrier SAL1	15238515	Sal1p, a calcium-dependent carrier protein that suppresses an essential cellular function associated With the Aac2 isoform of ADP/ATP translocase in Saccharomyces cerevisiae.

P34686	CAPZB_CAEEL	F-actin-capping protein subunit beta	8257793	The alpha and beta subunits of nematode actin capping protein function in yeast.

Q3E6R5	YD381_YEAST	Uncharacterized mitochondrial outer membrane protein YDR381C-A	16407407	Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins.

Q9BZE1	RM37_HUMAN	39S ribosomal protein L37, mitochondrial	11543634	The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders.

Q03944	VPS64_YEAST	Vacuolar protein sorting-associated protein 64	12134085	Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae.

Q9HDV9	GCSH_SCHPO	Putative glycine cleavage system H protein, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12224	RLM1_YEAST	Transcription factor RLM1	7565726	Yeast RLM1 encodes a serum response factor-like protein that may function downstream of the Mpk1 (Slt2) mitogen-activated protein kinase pathway.

P78536	ADA17_HUMAN	Disintegrin and metalloproteinase domain-containing protein 17	9034190	A metalloproteinase disintegrin that releases tumour-necrosis factor- alpha from cells.

P41996	CPG2_CAEEL	Chondroitin proteoglycan-2	16785326	Identification of novel chondroitin proteoglycans in Caenorhabditis elegans: embryonic cell division depends on CPG-1 and CPG-2.

P84690	SC58_TITCA	Toxin Tc58	15025998	Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

O80605	SUC3_ARATH	Sucrose transport protein SUC3	11135120	AtSUC3, a gene encoding a new Arabidopsis sucrose transporter, is expressed in cells adjacent to the vascular tissue and in a carpel cell layer.

Q9UTK4	NU189_SCHPO	Nucleoporin nup189	15226438	The fission yeast Nup107-120 complex functionally interacts with the small GTPase Ran/Spi1 and is required for mRNA export, nuclear pore distribution, and proper cell division.

Q7KUD5	INSL5_DROME	Probable insulin-like peptide 5	11250149	An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control.

Q93Z81	CAX3_ARATH	Vacuolar cation/proton exchanger 3	11562366	Structural determinants of Ca2+ transport in the Arabidopsis H+/Ca2+ antiporter CAX1.

Q3KQ35	S17AA_XENLA	Transcription factor Sox-17-alpha-A	16651540	Global analysis of the transcriptional network controlling Xenopus endoderm formation.

P53708	ITA8_HUMAN	Integrin alpha-8	7768999	Sequence and tissue distribution of the human integrin alpha 8 subunit: a beta 1-associated alpha subunit expressed in smooth muscle cells.

O89051	ITM2B_MOUSE	Integral membrane protein 2B	10679242	Growth suppression of Escherichia coli by induction of expression of mammalian genes with transmembrane or ATPase domains.

Q38946	DHE2_ARATH	Glutamate dehydrogenase 2	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q9SGD6	AROD6_ARATH	Arogenate dehydratase/prephenate dehydratase 6, chloroplastic	17726025	Phenylalanine biosynthesis in Arabidopsis thaliana. Identification and characterization of arogenate dehydratases.

P54855	UDB15_HUMAN	UDP-glucuronosyltransferase 2B15	7835232	Stable expression of a human liver UDP-glucuronosyltransferase (UGT2B15) with activity toward steroid and xenobiotic substrates.

Q9SU14	NUDT7_ARATH	Nudix hydrolase 7	17660350	AtNUDT7, a negative regulator of basal immunity in Arabidopsis, modulates two distinct defense response pathways and is involved in maintaining redox homeostasis.

Q9USG8	MU190_SCHPO	Meiotically up-regulated gene 190 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Z103	ADNP_MOUSE	Activity-dependent neuroprotector homeobox protein	10037502	Complete sequence of a novel protein containing a femtomolar- activity-dependent neuroprotective peptide.

P61086	UBE2K_HUMAN	Ubiquitin-conjugating enzyme E2 K	8702625	Huntingtin is ubiquitinated and interacts with a specific ubiquitin- conjugating enzyme.

Q62160	GDIR3_MOUSE	Rho GDP-dissociation inhibitor 3	8939998	RhoGDI-3 is a new GDP dissociation inhibitor (GDI). Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG.

Q9D2V7	CORO7_MOUSE	Coronin-7	15327992	Coronin 7, the mammalian POD-1 homologue, localizes to the Golgi apparatus.

P05219	TBB_SCHPO	Tubulin beta chain	9658169	Identification of novel temperature-sensitive lethal alleles in essential beta-tubulin and nonessential alpha 2-tubulin genes as fission yeast polarity mutants.

Q13573	SNW1_HUMAN	SNW domain-containing protein 1	16102918	CHES1/FOXN3 interacts with Ski-interacting protein and acts as a transcriptional repressor.

Q04446	GLGB_HUMAN	1,4-alpha-glucan-branching enzyme	8613547	Hepatic and neuromuscular forms of glycogen storage disease type IV caused by mutations in the same glycogen-branching enzyme gene.

Q57259	FLIN_AGRT5	Flagellar motor switch protein FliN	9161425	The Agrobacterium tumefaciens motor gene, motA, is in a linked cluster with the flagellar switch protein genes, fliG, fliM and fliN.

A0JPL0	ZN382_RAT	Zinc finger protein 382	9835615	KRAB-independent suppression of neoplastic cell growth by the novel zinc finger transcription factor KS1.

O94395	KU70_SCHPO	ATP-dependent DNA helicase II subunit 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P11308	ERG_HUMAN	Transcriptional regulator ERG	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

P40344	ATG3_YEAST	Autophagy-related protein 3	9023185	AUT1, a gene essential for autophagocytosis in the yeast Saccharomyces cerevisiae.

P43629	KI3L1_HUMAN	Killer cell immunoglobulin-like receptor 3DL1	7716543	Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells.

Q9LR78	BSU1_ARATH	Serine/threonine-protein phosphatase BSU1	14977918	Nuclear protein phosphatases with Kelch-repeat domains modulate the response to brassinosteroids in Arabidopsis.

O43120	UAP2_SCHPO	Splicing factor U2AF-associated protein 2	9371883	Molecular characterization of a novel fission yeast gene spUAP2 that interacts with the splicing factor spU2AF59.

P53355	DAPK1_HUMAN	Death-associated protein kinase 1	7828849	Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death.

Q15154	PCM1_HUMAN	Pericentriolar material 1 protein	8120099	PCM-1, A 228-kD centrosome autoantigen with a distinct cell cycle distribution.

Q86WU2	LDHD_HUMAN	Probable D-lactate dehydrogenase, mitochondrial	12127981	Identification of putative mammalian D-lactate dehydrogenase enzymes.

P18581	CTR2_MOUSE	Low affinity cationic amino acid transporter 2	8195186	Control of cationic amino acid transport and retroviral receptor functions in a membrane protein family.

Q9P4R5	CREC_EMENI	Catabolite repression protein creC	10852476	The Aspergillus nidulans creC gene involved in carbon catabolite repression encodes a WD40 repeat protein.

P06748	NPM_HUMAN	Nucleophosmin	11051553	Nucleophosmin/B23 is a target of CDK2/cyclin E in centrosome duplication.

P20366	TKN1_HUMAN	Protachykinin-1	1708336	Tachykinin (substance-P) gene expression in Leydig cells of the human and mouse testis.

Q08491	SKI7_YEAST	Superkiller protein 7	11027292	Function of the ski4p (Csl4p) and Ski7p proteins in 3'-to-5' degradation of mRNA.

P36224	JNM1_YEAST	Nuclear migration protein JNM1	9658168	The yeast dynactin complex is involved in partitioning the mitotic spindle between mother and daughter cells during anaphase B.

Q02563	SV2A_RAT	Synaptic vesicle glycoprotein 2A	8910372	Isoform-specific, calcium-regulated interaction of the synaptic vesicle proteins SV2 and synaptotagmin.

P39104	PIK1_YEAST	Phosphatidylinositol 4-kinase PIK1	8248783	Phosphatidylinositol 4-kinase: gene structure and requirement for yeast cell viability.

P31134	POTG_ECOLI	Putrescine transport ATP-binding protein potG	8416922	Characteristics of the operon for a putrescine transport system that maps at 19 minutes on the Escherichia coli chromosome.

Q16891	IMMT_HUMAN	Mitochondrial inner membrane protein	9168817	Mitofilin is a transmembrane protein of the inner mitochondrial membrane expressed as two isoforms.

P21583	SCF_HUMAN	Kit ligand	17662946	Structural basis for activation of the receptor tyrosine kinase KIT by stem cell factor.

P76135	YDEO_ECOLI	HTH-type transcriptional regulator ydeO	12694615	Regulatory network of acid resistance genes in Escherichia coli.

Q6NZQ4	PAXI1_MOUSE	PAX-interacting protein 1	10908331	PTIP, a novel BRCT domain-containing protein interacts with Pax2 and is associated with active chromatin.

Q9BXJ9	NAA15_HUMAN	N-alpha-acetyltransferase 15, NatA auxiliary subunit	12145306	Regulation of osteocalcin gene expression by a novel Ku antigen transcription factor complex.

Q71WH8	CBIO1_LISMF	Cobalt import ATP-binding protein CbiO 1	15115801	Whole genome comparisons of serotype 4b and 1/2a strains of the food- borne pathogen Listeria monocytogenes reveal new insights into the core genome components of this species.

P32797	CDC13_YEAST	Cell division control protein 13	10898792	The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase alpha and the telomerase- associated est1 protein.

O94477	MYO52_SCHPO	Myosin-52	11112691	Two type V myosins with non-overlapping functions in the fission yeast Schizosaccharomyces pombe: Myo52 is concerned with growth polarity and cytokinesis, Myo51 is a component of the cytokinetic actin ring.

P24807	CD24_MOUSE	Signal transducer CD24	2118158	Expression cloning of a cDNA encoding M1/69-J11d heat-stable antigens.

Q9SSL9	PEPR1_ARATH	Leucine-rich repeat receptor-like protein kinase PEPR1	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P18613	RAPA_DICDI	Ras-related protein rapA	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P38086	RDH54_YEAST	DNA repair and recombination protein RDH54	9409820	Characterization of the roles of the Saccharomyces cerevisiae RAD54 gene and a homologue of RAD54, RDH54/TID1, in mitosis and meiosis.

Q9SXZ2	FT_ARATH	Protein FLOWERING LOCUS T	16099979	FD, a bZIP protein mediating signals from the floral pathway integrator FT at the shoot apex.

Q9VWV9	PORCN_DROME	Protein-cysteine N-palmitoyltransferase porcupine	15166250	Drosophila wnt-1 undergoes a hydrophobic modification and is targeted to lipid rafts, a process that requires porcupine.

P53165	SGF73_YEAST	SAGA-associated factor 73	12052880	Proteomics of the eukaryotic transcription machinery: identification of proteins associated with components of yeast TFIID by multidimensional mass spectrometry.

P79996	MK09_CHICK	Mitogen-activated protein kinase 9	9177299	Expression of the JNK2-alpha1 gene in the developing chick brain.

Q64151	SEM4C_MOUSE	Semaphorin-4C	15811348	Requirement of the transmembrane semaphorin Sema4C for myogenic differentiation.

Q66HE5	NUAK2_RAT	NUAK family SNF1-like kinase 2	11284715	Identification and characterization of a novel sucrose-non-fermenting protein kinase/AMP-activated protein kinase-related protein kinase, SNARK.

Q92569	P55G_HUMAN	Phosphatidylinositol 3-kinase regulatory subunit gamma	9524259	Cloning of human p55 gamma, a regulatory subunit of phosphatidylinositol 3-kinase, by a yeast two-hybrid library screen with the insulin-like growth factor-I receptor.

P08985	H2AV_DROME	Histone H2A.v	10801889	Histone H2A.Z is widely but nonrandomly distributed in chromosomes of Drosophila melanogaster.

Q62698	DC1L2_RAT	Cytoplasmic dynein 1 light intermediate chain 2	7738094	Molecular analysis of a cytoplasmic dynein light intermediate chain reveals homology to a family of ATPases.

Q99220	OS9_YEAST	Protein OS-9 homolog	16168371	Yos9p detects and targets misfolded glycoproteins for ER-associated degradation.

Q07001	ACHD_HUMAN	Acetylcholine receptor subunit delta	18252226	Acetylcholine receptor pathway mutations explain various fetal akinesia deformation sequence disorders.

O49292	PPD4_ARATH	PsbP domain-containing protein 4, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

P17050	NAGAB_HUMAN	Alpha-N-acetylgalactosaminidase	19683538	The 1.9 A structure of human alpha-N-acetylgalactosaminidase: the molecular basis of Schindler and Kanzaki diseases.

P27654	TIP1_YEAST	Temperature shock-inducible protein 1	15781460	Comprehensive proteomic analysis of Saccharomyces cerevisiae cell walls: identification of proteins covalently attached via glycosylphosphatidylinositol remnants or mild alkali-sensitive linkages.

P46970	NMD5_YEAST	Nonsense-mediated mRNA decay protein 5	9852143	A novel nuclear import pathway for the transcription factor TFIIS.

O00488	ZN593_HUMAN	Zinc finger protein 593	9115366	A novel genetic system to isolate a dominant negative effector on DNA-binding activity of Oct-2.

P32305	5HT7R_RAT	5-hydroxytryptamine receptor 7	8394362	Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype.

Q9LHE7	FYPP3_ARATH	Phytochrome-associated serine/threonine protein phosphatase 3	12468726	A phytochrome-associated protein phosphatase 2A modulates light signals in flowering time control in Arabidopsis.

Q8BST6	PELI2_MOUSE	Protein pellino homolog 2	12370331	Mouse pellino-2 modulates IL-1 and lipopolysaccharide signaling.

O64989	C90B1_ARATH	Cytochrome P450 90B1	9490746	The DWF4 gene of Arabidopsis encodes a cytochrome P450 that mediates multiple 22alpha-hydroxylation steps in brassinosteroid biosynthesis.

P32479	HIR1_YEAST	Protein HIR1	16264190	The HIR corepressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF.

O95711	LY86_HUMAN	Lymphocyte antigen 86	9763566	RP105 is associated with MD-1 and transmits an activation signal in human B cells.

Q9V4C8	HCF_DROME	Host cell factor	12494450	Molecular cloning of Drosophila HCF reveals proteolytic processing and self-association of the encoded protein.

Q84Y18	CXIP4_ARATH	CAX-interacting protein 4	14960315	Characterization of CXIP4, a novel Arabidopsis protein that activates the H+/Ca2+ antiporter, CAX1.

Q3E769	YO59A_YEAST	Uncharacterized protein YOL159C-A	14562095	Global analysis of protein localization in budding yeast.

P32795	YME1_YEAST	Mitochondrial inner membrane i-AAA protease supercomplex subunit YME1	18843051	Mgr3p and Mgr1p are adaptors for the mitochondrial i-AAA protease complex.

Q9NZJ0	DTL_HUMAN	Denticleless protein homolog	20129063	CRL4(Cdt2) E3 ubiquitin ligase monoubiquitinates PCNA to promote translesion DNA synthesis.

Q04636	POB3_YEAST	FACT complex subunit POB3	9199353	The Saccharomyces cerevisiae DNA polymerase alpha catalytic subunit interacts with Cdc68/Spt16 and with Pob3, a protein similar to an HMG1-like protein.

Q2QYY8	PHT1A_ORYSJ	Phototropin-1A	12068117	Photochemical properties of the flavin mononucleotide-binding domains of the phototropins from Arabidopsis, rice, and Chlamydomonas reinhardtii.

P15496	IDI1_YEAST	Isopentenyl-diphosphate Delta-isomerase	2681212	Isopentenyl diphosphate:dimethylallyl diphosphate isomerase. An improved purification of the enzyme and isolation of the gene from Saccharomyces cerevisiae.

Q9UI09	NDUAC_HUMAN	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

O48670	RER1A_ARATH	Protein RER1A	10737146	The Arabidopsis thaliana RER1 gene family: its potential role in the endoplasmic reticulum localization of membrane proteins.

P02524	CRBB3_RAT	Beta-crystallin B3	3879970	Rat lens beta-crystallins are internally duplicated and homologous to gamma-crystallins.

O15067	PUR4_HUMAN	Phosphoribosylformylglycinamidine synthase	10548741	Human phosphoribosylformylglycinamide amidotransferase (FGARAT): regional mapping, complete coding sequence, isolation of a functional genomic clone, and DNA sequence analysis.

Q99942	RNF5_HUMAN	E3 ubiquitin-protein ligase RNF5	9533025	Cloning, expression and mapping of a novel RING-finger gene (RNF5), a human homologue of a putative zinc-finger gene from Caenorhabditis elegans.

Q12338	RNH2C_YEAST	Ribonuclease H2 subunit C	14734815	RNase H2 of Saccharomyces cerevisiae is a complex of three proteins.

P23566	UBC2_SCHPO	Ubiquitin-conjugating enzyme E2 2	16096059	Regulation of nuclear proteasome by Rhp6/Ubc2 through ubiquitination and destruction of the sensor and anchor Cut8.

O14920	IKKB_HUMAN	Inhibitor of nuclear factor kappa-B kinase subunit beta	11971985	Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) coactivator activity by I kappa B kinase.

Q8BHY3	ANO1_MOUSE	Anoctamin-1	18724360	TMEM16A confers receptor-activated calcium-dependent chloride conductance.

Q8W4D8	DDL_ARATH	FHA domain-containing protein DDL	16679419	DAWDLE, a forkhead-associated domain gene, regulates multiple aspects of plant development.

P43165	CAH5A_RAT	Carbonic anhydrase 5A, mitochondrial	7937950	Mitochondrial carbonic anhydrase (isozyme V) in mouse and rat: cDNA cloning, expression, subcellular localization, processing, and tissue distribution.

P43563	MOB2_YEAST	CBK1 kinase activator protein MOB2	11747810	Yeast Cbk1 and Mob2 activate daughter-specific genetic programs to induce asymmetric cell fates.

O14497	ARI1A_HUMAN	AT-rich interactive domain-containing protein 1A	12200431	Largest subunits of the human SWI/SNF chromatin-remodeling complex promote transcriptional activation by steroid hormone receptors.

Q9Z2N8	ACL6A_MOUSE	Actin-like protein 6A	9845365	Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling.

P25632	RSC6_YEAST	Chromatin structure-remodeling complex protein RSC6	9685490	Direct interaction between Rsc6 and Rsc8/Swh3, two proteins that are conserved in SWI/SNF-related complexes.

Q9VC27	NICA_DROME	Nicastrin	11781576	Nicastrin is required for Presenilin-mediated transmembrane cleavage in Drosophila.

P36618	CDC16_SCHPO	Cell division control protein 16	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9BZR9	TRIM8_HUMAN	Probable E3 ubiquitin-protein ligase TRIM8	11118312	A novel RING finger-B box-coiled-coil protein, GERP.

Q60848	HELLS_MOUSE	Lymphocyte-specific helicase	15105378	Growth retardation and premature aging phenotypes in mice with disruption of the SNF2-like gene, PASG.

O74385	YNVA_SCHPO	UPF0405 protein C3H7.10	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UII6	DUS13_HUMAN	Dual specificity protein phosphatase 13	10585869	Molecular cloning and characterization of a novel dual-specificity protein phosphatase possibly involved in spermatogenesis.

Q54NU2	RAB1D_DICDI	Ras-related protein Rab-1D	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

O15169	AXN1_HUMAN	Axin-1	9230313	The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation.

P63161	KCNE2_RAT	Potassium voltage-gated channel subfamily E member 2	10219239	MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia.

Q6QWF9	CK2N1_MOUSE	Calcium/calmodulin-dependent protein kinase II inhibitor 1	17350603	Characterization of mouse neuronal Ca2+/calmodulin kinase II inhibitor alpha.

O35129	PHB2_MOUSE	Prohibitin-2	11302691	Mammalian prohibitin proteins respond to mitochondrial stress and decrease during cellular senescence.

O14043	YEYA_SCHPO	Uncharacterized protein C2C4.10c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P50536	MSL3_DROME	Protein male-specific lethal-3	7768187	Molecular characterization of the male-specific lethal-3 gene and investigations of the regulation of dosage compensation in Drosophila.

Q8R4T2	SIAH2_RAT	E3 ubiquitin-protein ligase SIAH2	11786535	Regulation of synaptophysin degradation by mammalian homologues of Seven in Absentia.

Q9HCH5	SYTL2_HUMAN	Synaptotagmin-like protein 2	18940603	Elucidation of Rab27 recruitment by its effectors: structure of Rab27a bound to Exophilin4/Slp2-a.

Q04841	3MG_MOUSE	DNA-3-methyladenine glycosylase	8435858	Cloning and characterization of a mouse 3-methyladenine/7-methyl- guanine/3-methylguanine DNA glycosylase cDNA whose gene maps to chromosome 11.

Q9JHW5	VAMP7_RAT	Vesicle-associated membrane protein 7	14993220	Identification of SNAREs involved in synaptotagmin VII-regulated lysosomal exocytosis.

O89086	RBM3_MOUSE	Putative RNA-binding protein 3	15684048	Cold stress-induced protein Rbm3 binds 60S ribosomal subunits, alters microRNA levels, and enhances global protein synthesis.

Q9Y4X1	UD2A1_HUMAN	UDP-glucuronosyltransferase 2A1	10359671	Cloning and characterization of a novel human olfactory UDP- glucuronosyltransferase.

Q9BXL7	CAR11_HUMAN	Caspase recruitment domain-containing protein 11	17287217	Caveolin-1 triggers T-cell activation via CD26 in association with CARMA1.

Q02574	MEC3_YEAST	DNA damage checkpoint control protein MEC3	9891048	Role of a complex containing Rad17, Mec3, and Ddc1 in the yeast DNA damage checkpoint pathway.

Q9TW65	DMD_CAEEL	Dystrophin-1	10996789	Genetic suppression of phenotypes arising from mutations in dystrophin-related genes in Caenorhabditis elegans.

Q8S8F8	GEM_ARATH	GLABRA2 expression modulator	17450124	A chromatin link that couples cell division to root epidermis patterning in Arabidopsis.

P30550	GRPR_HUMAN	Gastrin-releasing peptide receptor	1655761	Two distinct bombesin receptor subtypes are expressed and functional in human lung carcinoma cells.

Q12301	YD180_YEAST	Uncharacterized membrane protein YDL180W	14562095	Global analysis of protein localization in budding yeast.

Q6W3E9	P4HA3_RAT	Prolyl 4-hydroxylase subunit alpha-3	14500733	Identification and characterization of a third human, rat, and mouse collagen prolyl 4-hydroxylase isoenzyme.

Q9WU42	NCOR2_MOUSE	Nuclear receptor corepressor 2	10640276	Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression.

P0A9J6	RBSK_ECOLI	Ribokinase	3011794	Ribokinase from Escherichia coli K12. Nucleotide sequence and overexpression of the rbsK gene and purification of ribokinase.

Q91ZE9	BMF_MOUSE	Bcl-2-modifying factor	11546872	Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis.

P01621	KV303_HUMAN	Ig kappa chain V-III region NG9	6419127	Most kappa immunoglobulin mRNA in human lymphocytes is homologous to a small family of germ-line V genes.

P26358	DNMT1_HUMAN	DNA (cytosine-5)-methyltransferase 1	18754681	CXXC domain of human DNMT1 is essential for enzymatic activity.

Q10297	IMB5_SCHPO	Importin subunit beta-5	15116432	Identification of genes encoding putative nucleoporins and transport factors in the fission yeast Schizosaccharomyces pombe: a deletion analysis.

Q86XR7	TCAM2_HUMAN	TIR domain-containing adapter molecule 2	12761501	Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.

Q811A2	BST2_RAT	Bone marrow stromal antigen 2	12956872	Bst-2/HM1.24 is a raft-associated apical membrane protein with an unusual topology.

P62161	CALM_RAT	Calmodulin	18056528	Rad GTPase deficiency leads to cardiac hypertrophy.

P23636	PP2A2_SCHPO	Major serine/threonine-protein phosphatase PP2A-2 catalytic subunit	2170029	Distinct, essential roles of type 1 and 2A protein phosphatases in the control of the fission yeast cell division cycle.

Q8RXN0	AB11G_ARATH	ABC transporter G family member 11	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P23492	PNPH_MOUSE	Purine nucleoside phosphorylase	1374046	Isolation and expression of a murine purine nucleoside phosphorylase- encoding cDNA and sequence similarity with the human message.

Q874R1	RHO4_SCHPO	GTP-binding protein rho4	12796297	Novel Rho GTPase involved in cytokinesis and cell wall integrity in the fission yeast Schizosaccharomyces pombe.

Q9M8W5	SIP11_ARATH	Aquaporin SIP1-1	16223486	Novel type aquaporin SIPs are mainly localized to the ER membrane and show cell-specific expression in Arabidopsis thaliana.

Q8NFQ6	BPIL2_HUMAN	Bactericidal/permeability-increasing protein-like 2	12185532	Three new human members of the lipid transfer/lipopolysaccharide binding protein family (LT/LBP).

Q92878	RAD50_HUMAN	DNA repair protein RAD50	11096100	RINT-1, a novel Rad50-interacting protein, participates in radiation- induced G2/M checkpoint control.

Q62267	SPR1B_MOUSE	Cornifin-B	9931436	Structure and organization of the genes encoding mouse small proline- rich proteins, mSPRR1A and 1B.

P02381	RMAR_YEAST	Ribosomal protein VAR1, mitochondrial	11278769	Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues.

Q8TAQ2	SMRC2_HUMAN	SWI/SNF complex subunit SMARCC2	8804307	Diversity and specialization of mammalian SWI/SNF complexes.

Q12118	SGT2_YEAST	Small glutamine-rich tetratricopeptide repeat-containing protein 2	14562095	Global analysis of protein localization in budding yeast.

Q9UJU2	LEF1_HUMAN	Lymphoid enhancer-binding factor 1	9751710	Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors.

O60674	JAK2_HUMAN	Tyrosine-protein kinase JAK2	19783980	JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatin.

Q96250	ATPG3_ARATH	ATP synthase subunit gamma, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q9Y3Z3	SAMH1_HUMAN	SAM domain and HD domain-containing protein 1	11064105	Identification of human homologue of mouse IFN-gamma induced protein from human dendritic cells.

Q8IPU5	GR77A_DROME	Putative gustatory receptor 77a	10710312	Candidate taste receptors in Drosophila.

Q99661	KIF2C_HUMAN	Kinesin-like protein KIF2C	14960279	Aurora B regulates MCAK at the mitotic centromere.

P47017	LSM1_YEAST	Sm-like protein LSm1	10761922	Yeast Sm-like proteins function in mRNA decapping and decay.

P32828	SLX5_YEAST	E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5	16387868	Genetic analysis connects SLX5 and SLX8 to the SUMO pathway in Saccharomyces cerevisiae.

Q03509	CALM6_ARATH	Calmodulin-6	8507825	Calmodulin isoforms in Arabidopsis encoded by multiple divergent mRNAs.

Q9V877	SUB_DROME	Kinesin-like protein subito	11973304	subito encodes a kinesin-like protein required for meiotic spindle pole formation in Drosophila melanogaster.

O96017	CHK2_HUMAN	Serine/threonine-protein kinase Chk2	10617473	Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome.

P81534	D103A_HUMAN	Beta-defensin 103	11085990	Isolation and characterization of human beta-defensin-3, a novel human inducible peptide antibiotic.

Q9ZR03	UCRIA_ARATH	Cytochrome b6-f complex iron-sulfur subunit, chloroplastic	12766230	Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.

Q61164	CTCF_MOUSE	Transcriptional repressor CTCF	18614575	Maternal depletion of CTCF reveals multiple functions during oocyte and preimplantation embryo development.

Q5IBH6	SPDYB_MOUSE	Speedy protein B	15611625	Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins.

Q9Y5R5	DMRT2_HUMAN	Doublesex- and mab-3-related transcription factor 2	10332030	A region of human chromosome 9p required for testis development contains two genes related to known sexual regulators.

P49821	NDUV1_HUMAN	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial	8288251	Chromosomal localization of the human gene encoding the 51-kDa subunit of mitochondrial complex I (NDUFV1) to 11q13.

Q05166	NUP59_YEAST	Nucleoporin ASM4	11283351	A comprehensive two-hybrid analysis to explore the yeast protein interactome.

P32386	YBT1_YEAST	ATP-dependent bile acid permease	9182565	A yeast ATP-binding cassette-type protein mediating ATP-dependent bile acid transport.

O00444	PLK4_HUMAN	Serine/threonine-protein kinase PLK4	17681131	Plk4-induced centriole biogenesis in human cells.

O70512	CISH_RAT	Cytokine-inducible SH2-containing protein	10579313	Endotoxin-induced inhibition of growth hormone receptor signaling in rat liver in vivo.

Q04637	IF4G1_HUMAN	Eukaryotic translation initiation factor 4 gamma 1	9878069	Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E.

Q19266	KPC3_CAEEL	Protein kinase C-like 3	9716526	Atypical protein kinase C cooperates with PAR-3 to establish embryonic polarity in Caenorhabditis elegans.

O59676	PDP1_SCHPO	PWWP domain-containing protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P01593	KV101_HUMAN	Ig kappa chain V-I region AG	4893682	The amino acid sequence of a kappa type Bence-Jones protein. 3. The complete sequence and the location of the disulfide bridges.

Q9P305	IGO2_YEAST	Protein IGO2	14562095	Global analysis of protein localization in budding yeast.

P0ACS5	ZNTR_ECOLI	HTH-type transcriptional regulator zntR	10048032	ZntR is a Zn(II)-responsive MerR-like transcriptional regulator of zntA in Escherichia coli.

Q6ER94	BAS1_ORYSJ	2-Cys peroxiredoxin BAS1, chloroplastic	19345687	A proposed reaction mechanism for rice NADPH thioredoxin reductase C, an enzyme with protein disulfide reductase activity.

Q96L92	SNX27_HUMAN	Sorting nexin-27	19555689	MCC, a new interacting protein for Scrib, is required for cell migration in epithelial cells.

Q058N4	MRS2B_ARATH	Magnesium transporter MRS2-11, chloroplastic	11752386	A novel family of magnesium transport genes in Arabidopsis.

Q10471	GALT2_HUMAN	Polypeptide N-acetylgalactosaminyltransferase 2	9295285	Substrate specificities of three members of the human UDP-N-acetyl- alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase family, GalNAc-T1, -T2, and -T3.

P10288	CADH2_CHICK	Cadherin-2	1638632	Identification of a neural alpha-catenin as a key regulator of cadherin function and multicellular organization.

P14927	QCR7_HUMAN	Cytochrome b-c1 complex subunit 7	3056408	Cloning and sequencing of a cDNA for human mitochondrial ubiquinone- binding protein of complex III.

O08602	RAE1A_MOUSE	Retinoic acid early-inducible protein 1-alpha	10894171	Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice.

Q9JKQ4	IRX5_MOUSE	Iroquois-class homeodomain protein IRX-5	16239150	The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient.

Q5S2C3	PIR_ARATH	Protein PIR	15294869	Interchangeable functions of Arabidopsis PIROGI and the human WAVE complex subunit SRA1 during leaf epidermal development.

Q8LJT8	TKI1_ARATH	TSL-kinase interacting protein 1	19962994	PAH-domain-specific interactions of the Arabidopsis transcription coregulator SIN3-LIKE1 (SNL1) with telomere-binding protein 1 and ALWAYS EARLY2 Myb-DNA binding factors.

Q27934	PHYL_DROME	Protein phyllopod	11032805	A role for Ebi in neuronal cell cycle control.

Q9SYC8	LPAT3_ARATH	1-acyl-sn-glycerol-3-phosphate acyltransferase 3	15772283	Ubiquitous and endoplasmic reticulum-located lysophosphatidyl acyltransferase, LPAT2, is essential for female but not male gametophyte development in Arabidopsis.

P18847	ATF3_HUMAN	Cyclic AMP-dependent transcription factor ATF-3	7515060	ATF3 and ATF3 delta Zip. Transcriptional repression versus activation by alternatively spliced isoforms.

P32447	ASF1_YEAST	Histone chaperone ASF1	11404324	Yeast ASF1 protein is required for cell cycle regulation of histone gene transcription.

Q9GZY6	NTAL_HUMAN	Linker for activation of T-cells family member 2	12486104	Non-T cell activation linker (NTAL): a transmembrane adaptor protein involved in immunoreceptor signaling.

P48431	SOX2_HUMAN	Transcription factor SOX-2	7849401	The cDNA sequence and chromosomal location of the human SOX2 gene.

P01568	IFN21_HUMAN	Interferon alpha-21	6163083	The structure of eight distinct cloned human leukocyte interferon cDNAs.

Q39243	TRXB1_ARATH	Thioredoxin reductase 1	8308900	Arabidopsis thaliana NAPHP thioredoxin reductase. cDNA characterization and expression of the recombinant protein in Escherichia coli.

Q1MTQ1	TEA2_SCHPO	Kinesin-like protein tea2	15665379	The EB1 homolog Mal3 stimulates the ATPase of the kinesin Tea2 by recruiting it to the microtubule.

Q9UTI4	MOA1_SCHPO	Monopolar attachment protein 1	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

P53193	JAC1_YEAST	J-type co-chaperone JAC1, mitochondrial	9813017	Suppressors of superoxide dismutase (SOD1) deficiency in Saccharomyces cerevisiae. Identification of proteins predicted to mediate iron-sulfur cluster assembly.

Q80W98	SGTB_RAT	Small glutamine-rich tetratricopeptide repeat-containing protein beta	12878599	A brain-specific isoform of small glutamine-rich tetratricopeptide repeat-containing protein binds to Hsc70 and the cysteine string protein.

O74560	RAF2_SCHPO	Rik1-associated factor 2	16024659	A Rik1-associated, cullin-dependent E3 ubiquitin ligase is essential for heterochromatin formation.

P68500	CNTN5_MOUSE	Contactin-5	12653969	Aberrant responses to acoustic stimuli in mice deficient for neural recognition molecule NB-2.

O00292	LFTY2_HUMAN	Left-right determination factor 2	9153275	Detection of ebaf, a novel human gene of the transforming growth factor beta superfamily association of gene expression with endometrial bleeding.

P53731	ARPC2_YEAST	Actin-related protein 2/3 complex subunit 2	9210376	The complex containing actin-related proteins Arp2 and Arp3 is required for the motility and integrity of yeast actin patches.

P51532	SMCA4_HUMAN	Transcription activator BRG1	16051670	hZimp7, a novel PIAS-like protein, enhances androgen receptor- mediated transcription and interacts with SWI/SNF-like BAF complexes.

Q24535	SRF_DROME	Serum response factor homolog	7600954	The Drosophila SRF homolog is expressed in a subset of tracheal cells and maps within a genomic region required for tracheal development.

P16677	PHNC_ECOLI	Phosphonates import ATP-binding protein PhnC	8388873	Mutational analysis of an Escherichia coli fourteen-gene operon for phosphonate degradation, using TnphoA' elements.

P43292	SRK2G_ARATH	Serine/threonine-protein kinase SRK2G	15292193	Identification of nine sucrose nonfermenting 1-related protein kinases 2 activated by hyperosmotic and saline stresses in Arabidopsis thaliana.

Q68FI1	L14BA_XENLA	Protein LSM14 homolog B-A	19458392	Participation of Xenopus Elr-type proteins in vegetal mRNA localization during oogenesis.

O00628	PEX7_HUMAN	Peroxisomal targeting signal 2 receptor	12522768	Identification of PEX7 as the second gene involved in Refsum disease.

Q13061	TRDN_HUMAN	Triadin	7588753	Molecular cloning of the cDNA encoding human skeletal muscle triadin and its localisation to chromosome 6q22-6q23.

Q96AQ6	PBIP1_HUMAN	Pre-B-cell leukemia transcription factor-interacting protein 1	10825160	Functional cloning and characterization of a novel nonhomeodomain protein that inhibits the binding of PBX1-HOX complexes to DNA.

Q9LDC0	FKB42_ARATH	42 kDa peptidyl-prolyl isomerase	14517332	TWISTED DWARF1, a unique plasma membrane-anchored immunophilin-like protein, interacts with Arabidopsis multidrug resistance-like transporters AtPGP1 and AtPGP19.

O00232	PSD12_HUMAN	26S proteasome non-ATPase regulatory subunit 12	9426256	cDNA cloning and functional analysis of p44.5 and p55, two regulatory subunits of the 26S proteasome.

Q54ET0	GRLE_DICDI	Metabotropic glutamate receptor-like protein E	16672332	GABA induces terminal differentiation of Dictyostelium through a GABAB receptor.

P0A9V1	LPTB_ECOLI	Lipopolysaccharide export system ATP-binding protein lptB	17056748	Characterization of lptA and lptB, two essential genes implicated in lipopolysaccharide transport to the outer membrane of Escherichia coli.

P32469	DPH5_YEAST	Diphthine synthase	1508200	DPH5, a methyltransferase gene required for diphthamide biosynthesis in Saccharomyces cerevisiae.

O00748	EST2_HUMAN	Carboxylesterase 2	9169443	Purification and cloning of a broad substrate specificity human liver carboxylesterase that catalyzes the hydrolysis of cocaine and heroin.

Q03124	RSC9_YEAST	Chromatin structure-remodeling complex subunit RSC9	12183366	Chromatin remodeling by RSC involves ATP-dependent DNA translocation.

Q8JGN5	BI51A_XENLA	Baculoviral IAP repeat-containing protein 5.1-A	17199039	Chromosomal enrichment and activation of the aurora B pathway are coupled to spatially regulate spindle assembly.

Q9JJ11	TACC3_MOUSE	Transforming acidic coiled-coil-containing protein 3	11025203	Isolation and characterization of AINT: a novel ARNT interacting protein expressed during murine embryonic development.

Q9UQ80	PA2G4_HUMAN	Proliferation-associated protein 2G4	15064750	EBP1 is a nucleolar growth-regulating protein that is part of pre- ribosomal ribonucleoprotein complexes.

Q8IUQ4	SIAH1_HUMAN	E3 ubiquitin-protein ligase SIAH1	16085652	Structural analysis of Siah1-Siah-interacting protein interactions and insights into the assembly of an E3 ligase multiprotein complex.

Q8GYN5	RIN4_ARATH	RPM1-interacting protein 4	12581526	Initiation of RPS2-specified disease resistance in Arabidopsis is coupled to the AvrRpt2-directed elimination of RIN4.

Q8N2S1	LTBP4_HUMAN	Latent-transforming growth factor beta-binding protein 4	9271198	Sequence and expression of a novel member (LTBP-4) of the family of latent transforming growth factor-beta binding proteins.

Q9SVT8	AMT14_ARATH	Ammonium transporter 1 member 4	19073648	AtAMT1;4, a pollen-specific high-affinity ammonium transporter of the plasma membrane in Arabidopsis.

P61086	UBE2K_HUMAN	Ubiquitin-conjugating enzyme E2 K	20061386	The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.

P38936	CDN1A_HUMAN	Cyclin-dependent kinase inhibitor 1	8242751	The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases.

Q7Z434	MAVS_HUMAN	Mitochondrial antiviral-signaling protein	12761501	Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.

P49914	MTHFS_HUMAN	5-formyltetrahydrofolate cyclo-ligase	8522195	Cloning and characterization of the human 5,10- methenyltetrahydrofolate synthetase-encoding cDNA.

O43708	MAAI_HUMAN	Maleylacetoacetate isomerase	10373324	Gene structure, chromosomal location, and expression pattern of maleylacetoacetate isomerase.

O94636	TRM11_SCHPO	tRNA guanosine-2'-O-methyltransferase trm11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P30740	ILEU_HUMAN	Leukocyte elastase inhibitor	1376927	Sequence and molecular characterization of human monocyte/neutrophil elastase inhibitor.

P41181	AQP2_HUMAN	Aquaporin-2	8140421	Requirement of human renal water channel aquaporin-2 for vasopressin- dependent concentration of urine.

Q93062	RBPMS_HUMAN	RNA-binding protein with multiple splicing	17099224	Potentiation of Smad-mediated transcriptional activation by the RNA- binding protein RBPMS.

Q63247	FOXJ1_RAT	Forkhead box protein J1	7753791	Primary structure of hepatocyte nuclear factor/forkhead homologue 4 and characterization of gene expression in the developing respiratory and reproductive epithelium.

P12392	ACHB4_RAT	Neuronal acetylcholine receptor subunit beta-4	1689727	Alpha 3, alpha 5, and beta 4: three members of the rat neuronal nicotinic acetylcholine receptor-related gene family form a gene cluster.

Q969H0	FBXW7_HUMAN	F-box/WD repeat-containing protein 7	17558397	The ubiquitin-specific protease USP28 is required for MYC stability.

P50416	CPT1A_HUMAN	Carnitine O-palmitoyltransferase 1, liver isoform	7892212	Human liver mitochondrial carnitine palmitoyltransferase I: characterization of its cDNA and chromosomal localization and partial analysis of the gene.

Q9C971	G3OX4_ARATH	Gibberellin 3-beta-dioxygenase 4	16181493	Purification and kinetic studies of recombinant gibberellin dioxygenases.

O60174	SFC6_SCHPO	Transcription factor tau subunit sfc6	10906331	Isolation and cloning of four subunits of a fission yeast TFIIIC complex that includes an ortholog of the human regulatory protein TFIIICbeta.

Q5U1Z0	RBGPR_RAT	Rab3 GTPase-activating protein non-catalytic subunit	9733780	Molecular cloning and characterization of the noncatalytic subunit of the Rab3 subfamily-specific GTPase-activating protein.

Q96L21	RL10L_HUMAN	60S ribosomal protein L10-like	12490704	Functional second genes generated by retrotransposition of the X- linked ribosomal protein genes.

P0A6M2	DSBB_ECOLI	Disulfide bond formation protein B	7957076	Two cysteines in each periplasmic domain of the membrane protein DsbB are required for its function in protein disulfide bond formation.

P22288	GCH1_RAT	GTP cyclohydrolase 1	7802677	Identification of a rabphilin-3A-interacting protein as GTP cyclohydrolase I in PC12 cells.

Q03713	AIM31_YEAST	Altered inheritance of mitochondria protein 31, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q5MNZ9	WIPI1_HUMAN	WD repeat domain phosphoinositide-interacting protein 1	15020712	PtdIns-specific MPR pathway association of a novel WD40 repeat protein, WIPI49.

P49598	P2C37_ARATH	Protein phosphatase 2C 37	9448270	Mutational analysis of protein phosphatase 2C involved in abscisic acid signal transduction in higher plants.

O08712	TR11B_MOUSE	Tumor necrosis factor receptor superfamily member 11B	9108485	Osteoprotegerin: a novel secreted protein involved in the regulation of bone density.

P47081	COX16_YEAST	Cytochrome c oxidase assembly protein COX16, mitochondrial	12446688	COX16 encodes a novel protein required for the assembly of cytochrome oxidase in Saccharomyces cerevisiae.

Q10021	RSP5_CAEEL	Probable splicing factor, arginine/serine-rich 5	10906451	Unique and redundant functions of SR proteins, a conserved family of splicing factors, in Caenorhabditis elegans development.

Q9P7I3	MDV1_SCHPO	Mitochondrial division protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O00425	IF2B3_HUMAN	Insulin-like growth factor 2 mRNA-binding protein 3	20080952	ZBP1 recognition of beta-actin zipcode induces RNA looping.

Q505F1	NR2C1_MOUSE	Nuclear receptor subfamily 2 group C member 1	11463856	The orphan nuclear receptor TR2 interacts directly with both class I and class II histone deacetylases.

P51692	STA5B_HUMAN	Signal transducer and activator of transcription 5B	8631883	Cloning of human Stat5B. Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cells.

Q9UTQ7	ARP9_SCHPO	SWI/SNF and RSC complexes subunit arp9	18622392	Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast.

Q28GG8	TBP_XENTR	TATA-box-binding protein	17703192	TBP paralogs accommodate metazoan- and vertebrate-specific developmental gene regulation.

P56715	RP1_HUMAN	Oxygen-regulated protein 1	10391211	Mutations in a gene encoding a new oxygen-regulated photoreceptor protein cause dominant retinitis pigmentosa.

Q9VYX1	ENY2_DROME	Enhancer of yellow 2 transcription factor	11438676	The novel transcription factor e(y)2 interacts with TAF(II)40 and potentiates transcription activation on chromatin templates.

P32909	SMY2_YEAST	Protein SMY2	16120600	GYF domain proteomics reveals interaction sites in known and novel target proteins.

P34556	CDK1_CAEEL	Cell division protein kinase 1	16343905	The conserved kinases CDK-1, GSK-3, KIN-19, and MBK-2 promote OMA-1 destruction to regulate the oocyte-to-embryo transition in C. elegans.

Q93725	NEDD8_CAEEL	NEDD8	15988528	The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae.

A4Q9E5	TTLL3_MOUSE	Tubulin monoglycylase TTLL3	19524510	Evolutionary divergence of enzymatic mechanisms for posttranslational polyglycylation.

P34804	COL40_CAEEL	Cuticle collagen 40	8299960	Identification, sequence and expression patterns of the Caenorhabditis elegans col-36 and col-40 collagen-encoding genes.

P53327	SLH1_YEAST	Antiviral helicase SLH1	11438647	Linking the 3' poly(A) tail to the subunit joining step of translation initiation: relations of Pab1p, eukaryotic translation initiation factor 5b (Fun12p), and Ski2p-Slh1p.

Q9UW13	PALF_CANAL	pH-response regulator protein palF/RIM8	10629054	RIM101-dependent and -independent pathways govern pH responses in Candida albicans.

P40996	SCD2_SCHPO	Protein scd2/ral3	7923372	Cooperative interaction of S. pombe proteins required for mating and morphogenesis.

Q15386	UBE3C_HUMAN	Ubiquitin-protein ligase E3C	12692129	Proteolytic targeting of transcriptional regulator TIP120B by a HECT domain E3 ligase.

P31539	HS104_YEAST	Heat shock protein 104	11867765	Analysis of the AAA sensor-2 motif in the C-terminal ATPase domain of Hsp104 with a site-specific fluorescent probe of nucleotide binding.

P50572	GBRR1_RAT	Gamma-aminobutyric acid receptor subunit rho-1	8524843	Cloning of a gamma-aminobutyric acid type C receptor subunit in rat retina with a methionine residue critical for picrotoxinin channel block.

Q01475	SAR1_SCHPO	Small COPII coat GTPase sar1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9YH09	RALBA_XENLA	Ras-related protein ralB-A	14576358	Control of embryonic Xenopus morphogenesis by a Ral-GDS/Xral branch of the Ras signalling pathway.

P0AFF0	NUON_ECOLI	NADH-quinone oxidoreductase subunit N	15919996	Global topology analysis of the Escherichia coli inner membrane proteome.

Q670P5	WNT11_XENLA	Protein Wnt-11	15708567	Wnt11-R, a protein closely related to mammalian Wnt11, is required for heart morphogenesis in Xenopus.

Q8W4L5	VAL1_ARATH	B3 domain-containing transcription repressor VAL1	15894743	Analysis of a sugar response mutant of Arabidopsis identified a novel B3 domain protein that functions as an active transcriptional repressor.

O15229	KMO_HUMAN	Kynurenine 3-monooxygenase	9237672	Cloning and functional expression of human kynurenine 3- monooxygenase.

P40694	SMBP2_MOUSE	DNA-binding protein SMUBP-2	19158098	IGHMBP2 is a ribosome-associated helicase inactive in the neuromuscular disorder distal SMA type 1 (DSMA1).

Q9YHZ5	PIM1_DANRE	Serine/threonine-protein kinase pim-1	10079300	Cloning of a cDNA encoding a pim1 homologue in zebrafish, Danio rerio.

Q9NAX4	SP65_DICDI	Spore coat protein SP65	17416892	Role of SP65 in assembly of the Dictyostelium discoideum spore coat.

P36625	REC7_SCHPO	Meiotic recombination protein rec7	1339382	Meiotically induced rec7 and rec8 genes of Schizosaccharomyces pombe.

O61667	EGL1_CAEEL	Programmed cell death activator egl-1	9604928	The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9.

O94301	HFI1_SCHPO	Transcriptional coactivator hfi1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q93YV7	PMT3_ARATH	Probable methyltransferase PMT3	16618929	Mapping the Arabidopsis organelle proteome.

Q63358	MYO9B_RAT	Myosin-IXb	7882973	A novel type of myosin implicated in signalling by rho family GTPases.

Q7Z465	BNIPL_HUMAN	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein	12681488	The apoptosis-associated protein BNIPL interacts with two cell proliferation-related proteins, MIF and GFER.

O43815	STRN_HUMAN	Striatin	9693043	Cloning of human striatin cDNA (STRN), gene mapping to 2p22-p21, and preferential expression in brain.

P13669	MNGR_ECOLI	Mannosyl-D-glycerate transport/metabolism system repressor mngR	7805834	Identification of a fatty acyl responsive regulator (FarR) in Escherichia coli.

P43132	BRE2_YEAST	COMPASS component BRE2	11742990	The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4.

P02489	CRYAA_HUMAN	Alpha-crystallin A chain	9467006	Autosomal dominant congenital cataract associated with a missense mutation in the human alpha crystallin gene CRYAA.

Q9XZL8	SRA_DROME	Protein sarah	16860744	The Drosophila calcipressin sarah is required for several aspects of egg activation.

O74335	RGA5_SCHPO	Rho-GTPase-activating protein 5	12519200	Rga5p is a specific Rho1p GTPase-activating protein that regulates cell integrity in Schizosaccharomyces pombe.

Q8CI19	PDGFC_MOUSE	Platelet-derived growth factor C	15372073	Tissue plasminogen activator is a potent activator of PDGF-CC.

Q15669	RHOH_HUMAN	Rho-related GTP-binding protein RhoH	11809807	The hematopoiesis-specific GTP-binding protein RhoH is GTPase deficient and modulates activities of other Rho GTPases by an inhibitory function.

Q99933	BAG1_HUMAN	BAG family molecular chaperone regulator 1	9305631	BAG-1 modulates the chaperone activity of Hsp70/Hsc70.

P15421	GLPE_HUMAN	Glycophorin-E	2295603	Identification of a novel human glycophorin, glycophorin E, by isolation of genomic clones and complementary DNA clones utilizing polymerase chain reaction.

Q04912	RON_HUMAN	Macrophage-stimulating protein receptor	7939629	Identification of the ron gene product as the receptor for the human macrophage stimulating protein.

Q20745	UNC84_CAEEL	Nuclear migration and anchoring protein unc-84	11907270	Lamin-dependent localization of UNC-84, a protein required for nuclear migration in Caenorhabditis elegans.

P80419	HV322_HUMAN	Ig heavy chain V-III region GAR	7737190	Characterization of the two unique human anti-flavin monoclonal immunoglobulins.

P34925	RYK_HUMAN	Tyrosine-protein kinase RYK	8726462	H-RYK, an unusual receptor kinase: isolation and analysis of expression in ovarian cancer.

Q07478	SUB2_YEAST	ATP-dependent RNA helicase SUB2	12411502	The mRNA export machinery requires the novel Sac3p-Thp1p complex to dock at the nucleoplasmic entrance of the nuclear pores.

Q8IXJ6	SIRT2_HUMAN	NAD-dependent deacetylase sirtuin-2	11427894	Structure of the histone deacetylase SIRT2.

Q8IWU4	ZNT8_HUMAN	Zinc transporter 8	16984975	In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion.

Q13619	CUL4A_HUMAN	Cullin-4A	17041588	CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation.

Q9LMT8	HDG12_ARATH	Homeobox-leucine zipper protein HDG12	16778018	Characterization of the class IV homeodomain-leucine zipper gene family in Arabidopsis.

Q7EZ57	HS188_ORYSJ	18.8 kDa class V heat shock protein	19703271	Rice sHsp genes: genomic organization and expression profiling under stress and development.

Q9NUK0	MBNL3_HUMAN	Muscleblind-like protein 3	15257297	Muscleblind proteins regulate alternative splicing.

Q02108	GCYA3_HUMAN	Guanylate cyclase soluble subunit alpha-3	1352257	Molecular cloning of the cDNAs coding for the two subunits of soluble guanylyl cyclase from human brain.

O81770	MGDG1_ARATH	Monogalactosyldiacylglycerol synthase 1, chloroplastic	17940034	Galactolipid synthesis in chloroplast inner envelope is essential for proper thylakoid biogenesis, photosynthesis, and embryogenesis.

O42888	YBN4_SCHPO	Uncharacterized oxidoreductase C8E4.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O14948	TFEC_HUMAN	Transcription factor EC	9256061	Molecular cloning of cDNA encoding a human TFEC isoform, a newly identified transcriptional regulator.

P04150	GCR_HUMAN	Glucocorticoid receptor	15941832	HEXIM1 forms a transcriptionally abortive complex with glucocorticoid receptor without involving 7SK RNA and positive transcription elongation factor b.

P33309	DOM34_YEAST	Protein DOM34	14562095	Global analysis of protein localization in budding yeast.

Q04206	TF65_HUMAN	Transcription factor p65	17620405	UXT is a novel and essential cofactor in the NF-kappaB transcriptional enhanceosome.

P13234	KCC4_RAT	Calcium/calmodulin-dependent protein kinase type IV	2538431	Ca2+/calmodulin-dependent protein kinase enriched in cerebellar granule cells. Identification of a novel neuronal calmodulin-dependent protein kinase.

Q09274	UN105_CAEEL	Degenerin-like protein unc-105	8662524	Interaction between a putative mechanosensory membrane channel and a collagen.

Q9UKK9	NUDT5_HUMAN	ADP-sugar pyrophosphatase	10567213	Cloning, expression and characterization of YSA1H, a human adenosine 5'-diphosphosugar pyrophosphatase possessing a MutT motif.

Q9VSU7	USE1_DROME	Vesicle transport protein USE1	16452979	Functional genomics reveals genes involved in protein secretion and Golgi organization.

Q13158	FADD_HUMAN	Protein FADD	7538907	FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis.

O08686	BARX2_MOUSE	Homeobox protein BarH-like 2	12486129	The homeodomain protein Barx2 promotes myogenic differentiation and is regulated by myogenic regulatory factors.

Q941L0	CESA3_ARATH	Cellulose synthase A catalytic subunit 3 [UDP-forming]	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q96DC9	OTUB2_HUMAN	Ubiquitin thioesterase OTUB2	18954305	Structural basis and specificity of human otubain 1-mediated deubiquitination.

Q9UTG1	PNPH_SCHPO	Putative purine nucleoside phosphorylase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P30283	CGS5_YEAST	S-phase entry cyclin-5	8319908	CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae.

Q9FPQ8	KNAT7_ARATH	Homeobox protein knotted-1-like 7	11701881	The Arabidopsis BELL1 and KNOX TALE homeodomain proteins interact through a domain conserved between plants and animals.

O14925	TIM23_HUMAN	Mitochondrial import inner membrane translocase subunit Tim23	15044455	Tim50, a component of the mitochondrial translocator, regulates mitochondrial integrity and cell death.

Q05930	MDM30_YEAST	Mitochondrial distribution and morphology protein 30	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q9P7T7	YIW3_SCHPO	UPF0647 protein C694.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9C107	MCL1_SCHPO	Minichromosome loss protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P19235	EPOR_HUMAN	Erythropoietin receptor	8506290	Truncated erythropoietin receptor causes dominantly inherited benign human erythrocytosis.

Q867Z4	LOLA4_DROME	Longitudinals lacking protein, isoforms F/I/K/T	11880341	Lola regulates midline crossing of CNS axons in Drosophila.

Q6STE5	SMRD3_HUMAN	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3	8804307	Diversity and specialization of mammalian SWI/SNF complexes.

O42934	CHP2_SCHPO	Chromo domain-containing protein 2	10835380	Four chromo-domain proteins of Schizosaccharomyces pombe differentially repress transcription at various chromosomal locations.

Q9VG97	GSTT3_DROME	Glutathione S-transferase D3	7683659	The glutathione S-transferase D genes. A divergently organized, intronless gene family in Drosophila melanogaster.

Q9QXT8	CSEN_MOUSE	Calsenilin	11792319	DREAM is a critical transcriptional repressor for pain modulation.

Q9LEU7	CIPK5_ARATH	CBL-interacting serine/threonine-protein kinase 5	11115898	Interaction specificity of Arabidopsis calcineurin B-like calcium sensors and their target kinases.

P43605	ECO1_YEAST	N-acetyltransferase ECO1	9990855	Ctf7p is essential for sister chromatid cohesion and links mitotic chromosome structure to the DNA replication machinery.

P76129	DOSP_ECOLI	Oxygen sensor protein DosP	15995192	The ubiquitous protein domain EAL is a cyclic diguanylate-specific phosphodiesterase: enzymatically active and inactive EAL domains.

Q9JJ50	HGS_RAT	Hepatocyte growth factor-regulated tyrosine kinase substrate	10825299	Hrs interacts with SNAP-25 and regulates Ca2+-dependent exocytosis.

Q27497	GLC7A_CAEEL	Serine/threonine-protein phosphatase PP1-alpha	11940606	The aurora kinase AIR-2 functions in the release of chromosome cohesion in Caenorhabditis elegans meiosis.

P61073	CXCR4_HUMAN	C-X-C chemokine receptor type 4	17077324	Endolyn (CD164) modulates the CXCL12-mediated migration of umbilical cord blood CD133+ cells.

Q10177	PDT1_SCHPO	Manganese transporter pdt1	14723709	Pmr1, a P-type ATPase, and Pdt1, an Nramp homologue, cooperatively regulate cell morphogenesis in fission yeast: the importance of Mn2+ homeostasis.

P32944	SWE1_YEAST	Mitosis inhibitor protein kinase SWE1	16360682	Swe1p responds to cytoskeletal perturbation, not bud size, in S. cerevisiae.

Q9NP78	ABCB9_HUMAN	ATP-binding cassette sub-family B member 9	11011155	A half-type ABC transporter TAPL is highly conserved between rodent and man, and the human gene is not responsive to interferon-gamma in contrast to TAP1 and TAP2.

O22527	CLH1_ARATH	Chlorophyllase-1	10611389	Cloning of chlorophyllase, the key enzyme in chlorophyll degradation: finding of a lipase motif and the induction by methyl jasmonate.

Q9NY56	OBP2A_HUMAN	Odorant-binding protein 2a	10607840	A novel human odorant-binding protein gene family resulting from genomic duplicons at 9q34: differential expression in the oral and genital spheres.

Q91989	P5F13_XENLA	POU domain, class 5, transcription factor 1.3	16860542	Xenopus POU factors of subclass V inhibit activin/nodal signaling during gastrulation.

O45876	APH1_CAEEL	Gamma-secretase subunit aph-1	12110170	aph-1 and pen-2 are required for Notch pathway signaling, gamma- secretase cleavage of betaAPP, and presenilin protein accumulation.

A2AIL4	CH038_MOUSE	UPF0551 protein C8orf38 homolog, mitochondrial	18614015	A mitochondrial protein compendium elucidates complex I disease biology.

Q9UUJ6	NED1_SCHPO	Nuclear elongation and deformation protein 1	12376568	An evolutionarily conserved fission yeast protein, Ned1, implicated in normal nuclear morphology and chromosome stability, interacts with Dis3, Pim1/RCC1 and an essential nucleoporin.

O75781	PALM_HUMAN	Paralemmin	9615234	Structure of the human paralemmin gene (PALM), mapping to human chromosome 19p13.3 and mouse chromosome 10, and exclusion of coding mutations in grizzled, mocha, jittery, and hesitant mice.

P38637	DBF8_YEAST	Protein DBF8	8065366	DBF8, an essential gene required for efficient chromosome segregation in Saccharomyces cerevisiae.

Q7TNJ0	TM7S4_MOUSE	Transmembrane 7 superfamily member 4	15452179	RANKL-induced DC-STAMP is essential for osteoclastogenesis.

O14595	CTDS2_HUMAN	Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2	12721286	A novel RNA polymerase II C-terminal domain phosphatase that preferentially dephosphorylates serine 5.

Q5RKZ7	MOCS1_MOUSE	Molybdenum cofactor biosynthesis protein 1	15862276	The pathogenesis of molybdenum cofactor deficiency, its delay by maternal clearance, and its expression pattern in microarray analysis.

P54659	MVPB_DICDI	Major vault protein beta	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q01593	ABI3_ARATH	B3 domain-containing transcription factor ABI3	15998807	The AIP2 E3 ligase acts as a novel negative regulator of ABA signaling by promoting ABI3 degradation.

O95864	FADS2_HUMAN	Fatty acid desaturase 2	9867867	Cloning, expression, and nutritional regulation of the mammalian Delta-6 desaturase.

P51843	NR0B1_HUMAN	Nuclear receptor subfamily 0 group B member 1	7990958	Mutations in the DAX-1 gene give rise to both X-linked adrenal hypoplasia congenita and hypogonadotropic hypogonadism.

Q9UBQ6	EXTL2_HUMAN	Exostosin-like 2	10639137	The putative tumor suppressors EXT1 and EXT2 form a stable complex that accumulates in the Golgi apparatus and catalyzes the synthesis of heparan sulfate.

Q9VJN5	WEK_DROME	Zinc finger protein weckle	16782008	Weckle is a zinc finger adaptor of the toll pathway in dorsoventral patterning of the Drosophila embryo.

P31539	HS104_YEAST	Heat shock protein 104	7984243	Protein disaggregation mediated by heat-shock protein Hsp104.

Q91W40	KLC3_MOUSE	Kinesin light chain 3	11319135	Kinesin light-chain KLC3 expression in testis is restricted to spermatids.

Q10587	TEF_HUMAN	Thyrotroph embryonic factor	7835883	Chromosomal localization and cDNA cloning of the human DBP and TEF genes.

P55064	AQP5_HUMAN	Aquaporin-5	8621489	The human aquaporin-5 gene. Molecular characterization and chromosomal localization.

Q9BV57	MTND_HUMAN	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase	11602742	Identification of a hepatic factor capable of supporting hepatitis C virus replication in a nonpermissive cell line.

Q9GSX9	RIC8_CAEEL	Synembryn	15479638	RGS-7 completes a receptor-independent heterotrimeric G protein cycle to asymmetrically regulate mitotic spindle positioning in C. elegans.

Q02085	SNAI1_MOUSE	Zinc finger protein SNAI1	11689706	The mouse snail gene encodes a key regulator of the epithelial- mesenchymal transition.

P35345	MC5R_RAT	Melanocortin receptor 5	8179577	Molecular cloning and characterization of the rat fifth melanocortin receptor.

P13437	THIM_RAT	3-ketoacyl-CoA thiolase, mitochondrial	3038520	cDNA-derived amino acid sequence of rat mitochondrial 3-oxoacyl-CoA thiolase with no transient presequence: structural relationship with peroxisomal isozyme.

P38882	UTP9_YEAST	U3 small nucleolar RNA-associated protein 9	15489292	RNA polymerase I transcription and pre-rRNA processing are linked by specific SSU processome components.

P32571	UBP4_YEAST	Ubiquitin carboxyl-terminal hydrolase 4	19410548	An inhibitor of a deubiquitinating enzyme regulates ubiquitin homeostasis.

Q9GZX6	IL22_HUMAN	Interleukin-22	10954742	Human interleukin-10-related T cell-derived inducible factor: molecular cloning and functional characterization as an hepatocyte- stimulating factor.

P13725	ONCM_HUMAN	Oncostatin-M	8999038	Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation.

Q9BYX4	IFIH1_HUMAN	Interferon-induced helicase C domain-containing protein 1	19881509	PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4.

P40482	SEC24_YEAST	Protein transport protein SEC24	12941277	Multiple cargo binding sites on the COPII subunit Sec24p ensure capture of diverse membrane proteins into transport vesicles.

P60900	PSA6_HUMAN	Proteasome subunit alpha type-6	7681138	The prosomal RNA-binding protein p27K is a member of the alpha-type human prosomal gene family.

O18388	IMB_DROME	Importin subunit beta	11102382	The Ketel gene encodes a Drosophila homologue of importin-beta.

Q9VEA5	RPB4_DROME	DNA-directed RNA polymerase II 16 kDa polypeptide	12482983	Two different Drosophila ADA2 homologues are present in distinct GCN5 histone acetyltransferase-containing complexes.

P48740	MASP1_HUMAN	Mannan-binding lectin serine protease 1	12421953	Characterization of the interaction between L-ficolin/p35 and mannan- binding lectin-associated serine proteases-1 and -2.

P09606	GLNA_RAT	Glutamine synthetase	1674354	Cloning and functional characterization of the rat glutamine synthetase gene.

O75486	SUPT3_HUMAN	Transcription initiation protein SPT3 homolog	9726987	A human SPT3-TAFII31-GCN5-L acetylase complex distinct from transcription factor IID.

P0A855	TOLB_ECOLI	Protein tolB	2687247	Nucleotide sequences of the tolA and tolB genes and localization of their products, components of a multistep translocation system in Escherichia coli.

Q8GXA4	WIP1_ARATH	WPP domain-interacting protein 1	17600715	Anchorage of plant RanGAP to the nuclear envelope involves novel nuclear-pore-associated proteins.

P60484	PTEN_HUMAN	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	10646847	Threonine phosphorylation of the MMAC1/PTEN PDZ binding domain both inhibits and stimulates PDZ binding.

P01772	HV311_HUMAN	Ig heavy chain V-III region KOL	6884994	Three-dimensional structure determination of antibodies. Primary structure of crystallized monoclonal immunoglobulin IgG1 KOL, I.

P34165	MFA1_YEAST	Mating hormone A-factor 1	3285180	The a-factor pheromone of Saccharomyces cerevisiae is essential for mating.

Q8ID94	YPF12_PLAF7	Uncharacterized protein MAL13P1.304	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

P33418	XPOT_YEAST	Exportin-T	9774653	Yeast Los1p has properties of an exportin-like nucleocytoplasmic transport factor for tRNA.

Q54C92	CSN6_DICDI	COP9 signalosome complex subunit 6	16781008	The COP9 signalosome regulates cell proliferation of Dictyostelium discoideum.

Q9UTC6	ISU1_SCHPO	Iron sulfur cluster assembly protein 1, mitochondrial	11939799	Characterization of an iron-sulfur cluster assembly protein (ISU1) from Schizosaccharomyces pombe.

Q9UJM3	ERRFI_HUMAN	ERBB receptor feedback inhibitor 1	18046415	Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface.

Q9UHN1	DPOG2_HUMAN	DNA polymerase subunit gamma-2, mitochondrial	9153213	Accessory subunit of mitochondrial DNA polymerase from Drosophila embryos. Cloning, molecular analysis, and association in the native enzyme.

P49956	CTF18_YEAST	Chromosome transmission fidelity protein 18	12665596	Mechanical link between cohesion establishment and DNA replication: Ctf7p/Eco1p, a cohesion establishment factor, associates with three different replication factor C complexes.

Q08963	RU2A_YEAST	U2 small nuclear ribonucleoprotein A'	9799242	The yeast U2A'/U2B complex is required for pre-spliceosome formation.

Q08966	PCL8_YEAST	PHO85 cyclin-8	9584169	Cyclin partners determine Pho85 protein kinase substrate specificity in vitro and in vivo: control of glycogen biosynthesis by Pcl8 and Pcl10.

Q86JE1	Y2130_DICDI	Recoverin family protein DDB_G0272130	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P0A9J4	PANE_ECOLI	2-dehydropantoate 2-reductase	10736170	Kinetic and mechanistic analysis of the E. coli panE-encoded ketopantoate reductase.

Q9Y7S9	AMY3_SCHPO	Alpha-amylase 3	16751704	An alpha-amylase homologue, aah3, encodes a GPI-anchored membrane protein required for cell wall integrity and morphogenesis in Schizosaccharomyces pombe.

Q16610	ECM1_HUMAN	Extracellular matrix protein 1	9367673	The human extracellular matrix gene 1 (ECM1): genomic structure, cDNA cloning, expression pattern, and chromosomal localization.

P22579	SIN3_YEAST	Transcriptional regulatory protein SIN3	15143171	The Rpd3-Sin3 histone deacetylase regulates replication timing and enables intra-S origin control in Saccharomyces cerevisiae.

P21580	TNAP3_HUMAN	Tumor necrosis factor alpha-induced protein 3	15258597	De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling.

Q8N2W9	PIAS4_HUMAN	E3 SUMO-protein ligase PIAS4	9724754	Inhibition of Stat1-mediated gene activation by PIAS1.

P42752	CCD21_ARATH	Cyclin-D2-1	11096103	The Arabidopsis D-type cyclins CycD2 and CycD3 both interact in vivo with the PSTAIRE cyclin-dependent kinase Cdc2a but are differentially controlled.

Q96VB6	XYNF3_ASPOR	Endo-1,4-beta-xylanase F3	11999400	Molecular cloning, characterization, and expression analysis of the xynF3 gene from Aspergillus oryzae.

P10153	RNAS2_HUMAN	Non-secretory ribonuclease	12855582	Eosinophil-derived neurotoxin (EDN), an antimicrobial protein with chemotactic activities for dendritic cells.

P02458	CO2A1_HUMAN	Collagen alpha-1(II) chain	16752401	High efficiency of mutation detection in type 1 stickler syndrome using a two-stage approach: vitreoretinal assessment coupled with exon sequencing for screening COL2A1.

Q07837	SLC31_HUMAN	Neutral and basic amino acid transport protein rBAT	8054986	Cystinuria caused by mutations in rBAT, a gene involved in the transport of cystine.

Q24572	CAF1_DROME	Probable histone-binding protein Caf1	8524837	Assembly of regularly spaced nucleosome arrays by Drosophila chromatin assembly factor 1 and a 56-kDa histone-binding protein.

P15303	SEC23_YEAST	Protein transport protein SEC23	12239560	Structure of the Sec23/24-Sar1 pre-budding complex of the COPII vesicle coat.

Q43125	CRY1_ARATH	Cryptochrome-1	15805487	N-terminal domain-mediated homodimerization is required for photoreceptor activity of Arabidopsis CRYPTOCHROME 1.

P31480	CYB6_EUGGR	Cytochrome b6	12837550	Cytochrome f and subunit IV, two essential components of the photosynthetic bf complex typically encoded in the chloroplast genome, are nucleus-encoded in Euglena gracilis.

Q9Y221	NIP7_HUMAN	60S ribosome subunit biogenesis protein NIP7 homolog	14660641	A novel human nucleolar protein, Nop132, binds to the G proteins, RRAG A/C/D.

P24783	DBP2_YEAST	ATP-dependent RNA helicase DBP2	14562095	Global analysis of protein localization in budding yeast.

Q14686	NCOA6_HUMAN	Nuclear receptor coactivator 6	12039952	Identification of protein arginine methyltransferase 2 as a coactivator for estrogen receptor alpha.

P38218	POA1_YEAST	ADP-ribose 1''-phosphate phosphatase	10550052	A biochemical genomics approach for identifying genes by the activity of their products.

O87237	LANA2_LACLA	Lantibiotic lacticin 3147 A2	10608807	Extensive post-translational modification, including serine to D- alanine conversion, in the two-component lantibiotic, lacticin 3147.

Q8BLY7	HPS6_MOUSE	Hermansky-Pudlak syndrome 6 protein homolog	12548288	Ru2 and Ru encode mouse orthologs of the genes mutated in human Hermansky-Pudlak syndrome types 5 and 6.

P32597	STH1_YEAST	Nuclear protein STH1/NPS1	9799253	Sth1p, a Saccharomyces cerevisiae Snf2p/Swi2p homolog, is an essential ATPase in RSC and differs from Snf/Swi in its interactions with histones and chromatin-associated proteins.

P46527	CDN1B_HUMAN	Cyclin-dependent kinase inhibitor 1B	8033212	Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals.

Q9UMQ3	BARX2_HUMAN	Homeobox protein BarH-like 2	10854790	Cloning and chromosomal localization of the human BARX2 homeobox protein gene.

B7U540	IRK18_HUMAN	Inward rectifier potassium channel 18	20074522	Mutations in potassium channel Kir2.6 cause susceptibility to thyrotoxic hypokalemic periodic paralysis.

O74505	YJD2_SCHPO	Uncharacterized protein C594.02c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8I0P1	SPAST_DROME	Spastin	19341724	Drosophila Atlastin regulates the stability of muscle microtubules and is required for synapse development.

O94405	YQFD_SCHPO	Uncharacterized protein C126.13c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Y6K9	NEMO_HUMAN	NF-kappa-B essential modulator	11971985	Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) coactivator activity by I kappa B kinase.

O95352	ATG7_HUMAN	Ubiquitin-like modifier-activating enzyme ATG7	11825910	Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p.

O00548	DLL1_HUMAN	Delta-like protein 1	11581320	Differential effects of Notch ligands Delta-1 and Jagged-1 in human lymphoid differentiation.

P45563	XAPA_ECOLI	Xanthosine phosphorylase	7559336	Identification and characterization of genes (xapA, xapB, and xapR) involved in xanthosine catabolism in Escherichia coli.

Q7ZW57	CCD89_XENLA	Coiled-coil domain-containing protein 89	14648848	Identification of BOIP, a novel cDNA highly expressed during spermatogenesis that encodes a protein interacting with the orange domain of the hairy-related transcription factor HRT1/Hey1 in Xenopus and mouse.

P82996	GSTE_PSEPU	Glutathione S-transferase	11900268	Occurence and properties of glutathione S-transferases in phenol- degrading Pseudomonas strains.

P55034	PSMD4_ARATH	26S proteasome non-ATPase regulatory subunit 4	12671091	The pleiotropic role of the 26S proteasome subunit RPN10 in Arabidopsis growth and development supports a substrate-specific function in abscisic acid signaling.

Q9ERH4	NUSAP_MOUSE	Nucleolar and spindle-associated protein 1	12963707	NuSAP, a novel microtubule-associated protein involved in mitotic spindle organization.

P53311	FMP43_YEAST	UPF0041 protein FMP43	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P11150	LIPC_HUMAN	Hepatic triacylglycerol lipase	2839510	Isolation and cDNA sequence of human postheparin plasma hepatic triglyceride lipase.

P53938	EOS1_YEAST	N-glycosylation protein EOS1	17187761	EOS1, whose deletion confers sensitivity to oxidative stress, is involved in N-glycosylation in Saccharomyces cerevisiae.

P30022	VP22_BHV1C	Tegument protein VP22	16140763	Characterization of the nuclear localization and nuclear export signals of bovine herpesvirus 1 VP22.

Q08905	FRE3_YEAST	Ferric reductase transmembrane component 3	11120744	The role of the FRE family of plasma membrane reductases in the uptake of siderophore-iron in Saccharomyces cerevisiae.

P18834	COL14_CAEEL	Cuticle collagen 14	2753356	Sequence comparisons of developmentally regulated collagen genes of Caenorhabditis elegans.

Q9LZ03	TOP6A_ARATH	DNA topoisomerase 6 subunit A	11410368	Molecular characterization of homologues of both subunits A (SPO11) and B of the archaebacterial topoisomerase 6 in plants.

Q8NDV7	TNR6A_HUMAN	Trinucleotide repeat-containing gene 6A protein	17671087	Let-7 microRNA-mediated mRNA deadenylation and translational repression in a mammalian cell-free system.

Q9ZVF5	WOX6_ARATH	WUSCHEL-related homeobox 6	15659481	The PRETTY FEW SEEDS2 gene encodes an Arabidopsis homeodomain protein that regulates ovule development.

P19634	SL9A1_HUMAN	Sodium/hydrogen exchanger 1	11696366	Human homolog of mouse tescalcin associates with Na(+)/H(+) exchanger type-1.

Q02750	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	8388392	Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2.

Q9ZPR7	UPS1_ARATH	Ureide permease 1	11971139	A novel superfamily of transporters for allantoin and other oxo derivatives of nitrogen heterocyclic compounds in Arabidopsis.

P84276	PA1C_RANPA	Palustrin-1c	15128283	Brevinin-1 and multiple insulin-releasing peptides in the skin of the frog Rana palustris.

Q9USJ5	DCUP_SCHPO	Uroporphyrinogen decarboxylase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O60110	OCA3_SCHPO	TPR repeat protein oca3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q39191	WAK1_ARATH	Wall-associated receptor kinase 1	8702686	A cell wall-associated, receptor-like protein kinase.

Q9VK45	TOR_DROME	Target of rapamycin	12559758	Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control.

P51437	CRAMP_MOUSE	Cathelin-related antimicrobial peptide	9148921	Identification of CRAMP, a cathelin-related antimicrobial peptide expressed in the embryonic and adult mouse.

O60496	DOK2_HUMAN	Docking protein 2	9478921	Molecular cloning and characterization of p56dok-2 defines a new family of RasGAP-binding proteins.

Q99MH6	NKD1_MOUSE	Protein naked cuticle homolog 1	11356022	Vertebrate proteins related to Drosophila Naked Cuticle bind Dishevelled and antagonize Wnt signaling.

Q9FF80	SUVH1_ARATH	Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH1	11691919	The Arabidopsis thaliana genome contains at least 29 active genes encoding SET domain proteins that can be assigned to four evolutionarily conserved classes.

Q96KQ4	ASPP1_HUMAN	Apoptosis-stimulating of p53 protein 1	11684014	ASPP proteins specifically stimulate the apoptotic function of p53.

O35704	SPTC1_MOUSE	Serine palmitoyltransferase 1	9363775	Human and murine serine-palmitoyl-CoA transferase. Cloning, expression and characterization of the key enzyme in sphingolipid synthesis.

Q9Z1W4	GDF11_MOUSE	Growth/differentiation factor 11	10391213	Regulation of anterior/posterior patterning of the axial skeleton by growth/differentiation factor 11.

Q8NBJ4	GOLM1_HUMAN	Golgi membrane protein 1	10831838	GP73, a novel Golgi-localized protein upregulated by viral infection.

O97239	DOP1_PLAF7	Protein dopey homolog PFC0245c	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

Q01628	IFM3_HUMAN	Interferon-induced transmembrane protein 3	1906403	Molecular analysis of a human interferon-inducible gene family.

O60114	YG65_SCHPO	Uncharacterized helicase C15C4.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P06169	PDC1_YEAST	Pyruvate decarboxylase isozyme 1	14562095	Global analysis of protein localization in budding yeast.

P23468	PTPRD_HUMAN	Receptor-type tyrosine-protein phosphatase delta	7896816	Molecular characterization of the human transmembrane protein- tyrosine phosphatase delta. Evidence for tissue-specific expression of alternative human transmembrane protein-tyrosine phosphatase delta isoforms.

Q9USU1	EFC25_SCHPO	Ras guanine nucleotide exchange factor efc25	9256078	Cloning and characterization of the S. pombe gene efc25+, a new putative guanine nucleotide exchange factor.

Q16534	HLF_HUMAN	Hepatic leukemia factor	1386162	Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia.

Q8VBV7	CSN8_MOUSE	COP9 signalosome complex subunit 8	14636993	Gene structure and embryonic expression of mouse COP9 signalosome subunit 8 (Csn8).

Q99607	ELF4_HUMAN	ETS-related transcription factor Elf-4	14976184	Myeloid Elf-1-like factor, an ETS transcription factor, up-regulates lysozyme transcription in epithelial cells through interaction with promyelocytic leukemia protein.

Q8H174	IAA31_ARATH	Auxin-responsive protein IAA31	12036262	Genetics of Aux/IAA and ARF action in plant growth and development.

Q9M1R4	IAA30_ARATH	Auxin-responsive protein IAA30	12036262	Genetics of Aux/IAA and ARF action in plant growth and development.

P14772	BPT1_YEAST	Bile pigment transporter 1	10790694	The products of YCF1 and YLL015w (BPT1) cooperate for the ATP- dependent vacuolar transport of unconjugated bilirubin in Saccharomyces cerevisiae.

Q9NAN2	PAR6_CAEEL	Partitioning defective protein 6	11412997	CDC-42 controls early cell polarity and spindle orientation in C. elegans.

Q9P7C9	DCPS_SCHPO	Scavenger mRNA-decapping enzyme DcpS	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P53093	YIP4_YEAST	Protein YIP4	17178117	Tvp38, Tvp23, Tvp18 and Tvp15: novel membrane proteins in the Tlg2- containing Golgi/endosome compartments of Saccharomyces cerevisiae.

Q15388	TOM20_HUMAN	Mitochondrial import receptor subunit TOM20 homolog	7498524	A human homolog of the mitochondrial protein import receptor Mom19 can assemble with the yeast mitochondrial receptor complex.

P82347	SGCD_MOUSE	Delta-sarcoglycan	10448073	Developmental expression of sarcoglycan gene products in cultured myocytes.

P32239	GASR_HUMAN	Gastrin/cholecystokinin type B receptor	7681836	The human brain cholecystokinin-B/gastrin receptor. Cloning and characterization.

P39748	FEN1_HUMAN	Flap endonuclease 1	8621570	Essential amino acids for substrate binding and catalysis of human flap endonuclease 1.

Q9UKX7	NUP50_HUMAN	Nuclear pore complex protein Nup50	10449902	Mapping and complex expression pattern of the human NPAP60L nucleoporin gene.

Q9NZP0	OR6C3_HUMAN	Olfactory receptor 6C3	10706615	The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates.

Q8NG31	CASC5_HUMAN	Protein CASC5	15502821	A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1.

P25297	PHO84_YEAST	Inorganic phosphate transporter PHO84	2038328	The PHO84 gene of Saccharomyces cerevisiae encodes an inorganic phosphate transporter.

Q13510	ASAH1_HUMAN	Acid ceramidase	8955159	Molecular cloning and characterization of a full-length complementary DNA encoding human acid ceramidase. Identification of the first molecular lesion causing Farber disease.

P15498	VAV_HUMAN	Proto-oncogene vav	15558030	Characterization of VIK-1: a new Vav-interacting Kruppel-like protein.

P35869	AHR_HUMAN	Aryl hydrocarbon receptor	12213388	Role of the aryl hydrocarbon receptor in cell cycle regulation.

A8E0R9	GRIP2_XENLA	Glutamate receptor-interacting protein 2	17924960	The efficiency of Xenopus primordial germ cell migration depends on the germplasm mRNA encoding the PDZ domain protein Grip2.

Q9QXU9	PCSK1_RAT	ProSAAS	15935061	Embryonic gene expression and pro-protein processing of proSAAS during rodent development.

O77460	IPYR_DROME	Inorganic pyrophosphatase	9784495	Inorganic pyrophosphatase is a component of the Drosophila nucleosome remodeling factor complex.

P57727	TMPS3_HUMAN	Transmembrane protease serine 3	12393794	The transmembrane serine protease (TMPRSS3) mutated in deafness DFNB8/10 activates the epithelial sodium channel (ENaC) in vitro.

Q93794	SEL10_CAEEL	F-box/WD repeat-containing protein sel-10	8293978	Suppressors of a lin-12 hypomorph define genes that interact with both lin-12 and glp-1 in Caenorhabditis elegans.

P46309	GSH1_ARATH	Glutamate--cysteine ligase, chloroplastic	15180996	Arabidopsis thaliana glutamate-cysteine ligase: functional properties, kinetic mechanism, and regulation of activity.

O70194	EIF3D_MOUSE	Eukaryotic translation initiation factor 3 subunit D	17581632	Reconstitution reveals the functional core of mammalian eIF3.

Q06263	VTA1_YEAST	Vacuolar protein sorting-associated protein VTA1	16505166	Recycling of ESCRTs by the AAA-ATPase Vps4 is regulated by a conserved VSL region in Vta1.

Q92466	DDB2_HUMAN	DNA damage-binding protein 2	17041588	CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation.

O54962	BAF_MOUSE	Barrier-to-autointegration factor	9465049	A previously unidentified host protein protects retroviral DNA from autointegration.

O94622	YBKD_SCHPO	Uncharacterized alpha-1,2-galactosyltransferase C1289.13c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P20309	ACM3_HUMAN	Muscarinic acetylcholine receptor M3	3443095	Distinct primary structures, ligand-binding properties and tissue- specific expression of four human muscarinic acetylcholine receptors.

P40191	PDXK_ECOLI	Pyridoxine kinase	8764513	Identification of the pdxK gene that encodes pyridoxine (vitamin B6) kinase in Escherichia coli K-12.

Q13233	M3K1_HUMAN	Mitogen-activated protein kinase kinase kinase 1	17906693	Negative regulation of MEKK1/2 signaling by serine-threonine kinase 38 (STK38).

O08919	NUMBL_MOUSE	Numb-like protein	9169836	Differential expression of mammalian Numb, Numblike and Notch1 suggests distinct roles during mouse cortical neurogenesis.

Q9Y7X2	YOP2_SCHPO	N-terminal acetyltransferase A complex subunit-like protein C418.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P39009	DUN1_YEAST	DNA damage response protein kinase DUN1	11953437	Posttranscriptional regulation of the RAD5 DNA repair gene by the Dun1 kinase and the Pan2-Pan3 poly(A)-nuclease complex contributes to survival of replication blocks.

Q06548	APK1A_ARATH	Protein kinase APK1A, chloroplastic	1450380	Novel protein kinase of Arabidopsis thaliana (APK1) that phosphorylates tyrosine, serine and threonine.

Q13219	PAPP1_HUMAN	Pappalysin-1	7508748	Amino acid sequence of human pregnancy-associated plasma protein-A derived from cloned cDNA.

Q13164	MK07_HUMAN	Mitogen-activated protein kinase 7	7646528	Primary structure of BMK1: a new mammalian map kinase.

Q15648	MED1_HUMAN	Mediator of RNA polymerase II transcription subunit 1	9653119	The TRAP220 component of a thyroid hormone receptor-associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion.

P11557	DAMX_ECOLI	Protein damX	7603433	Characterization of three genes in the dam-containing operon of Escherichia coli.

P32905	RSSA1_YEAST	40S ribosomal protein S0-A	14627813	Ribosomal proteins Rps0 and Rps21 of Saccharomyces cerevisiae have overlapping functions in the maturation of the 3' end of 18S rRNA.

P35465	PAK1_RAT	Serine/threonine-protein kinase PAK 1	8107774	A brain serine/threonine protein kinase activated by Cdc42 and Rac1.

P46736	BRCC3_HUMAN	Lys-63-specific deubiquitinase BRCC36	19261746	MERIT40 controls BRCA1-Rap80 complex integrity and recruitment to DNA double-strand breaks.

Q13046	PSG7_HUMAN	Putative pregnancy-specific beta-1-glycoprotein 7	1690992	The human pregnancy-specific glycoprotein genes are tightly linked on the long arm of chromosome 19 and are coordinately expressed.

Q9CQB5	CISD2_MOUSE	CDGSH iron-sulfur domain-containing protein 2	19451219	Cisd2 deficiency drives premature aging and causes mitochondria- mediated defects in mice.

Q7ZYB4	PAIP1_XENLA	Polyadenylate-binding protein-interacting protein 1	15713657	Embryonic poly(A)-binding protein stimulates translation in germ cells.

P53320	MTM1_YEAST	Mitochondrial carrier protein MTM1	12890866	Manganese activation of superoxide dismutase 2 in Saccharomyces cerevisiae requires MTM1, a member of the mitochondrial carrier family.

O35381	AN32A_MOUSE	Acidic leucine-rich nuclear phosphoprotein 32 family member A	9353121	The cerebellar leucine-rich acidic nuclear protein interacts with ataxin-1.

P40528	SYG1_YEAST	Protein SYG1	7592711	Truncated forms of a novel yeast protein suppress the lethality of a G protein alpha subunit deficiency by interacting with the beta subunit.

Q01519	COX12_YEAST	Cytochrome c oxidase subunit 6B	1331058	Purification of yeast cytochrome c oxidase with a subunit composition resembling the mammalian enzyme.

P03406	NEF_HV1BR	Protein Nef	7859737	Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4.

Q04839	GFD1_YEAST	mRNA transport factor GFD1	10610322	The RNA export factor Gle1p is located on the cytoplasmic fibrils of the NPC and physically interacts with the FG-nucleoporin Rip1p, the DEAD-box protein Rat8p/Dbp5p and a new protein Ymr255p.

Q4VA61	DSCL1_MOUSE	Down syndrome cell adhesion molecule-like protein 1 homolog	19945391	DSCAM and DSCAML1 function in self-avoidance in multiple cell types in the developing mouse retina.

P56484	CCR8_MOUSE	C-C chemokine receptor type 8	9670926	The chemokine receptor CCR8 is preferentially expressed in Th2 but not Th1 cells.

Q96RI1	NR1H4_HUMAN	Bile acid receptor	10334993	Bile acids: natural ligands for an orphan nuclear receptor.

O35161	CELR1_MOUSE	Cadherin EGF LAG seven-pass G-type receptor 1	9339365	Celsr1, a neural-specific gene encoding an unusual seven-pass transmembrane receptor, maps to mouse chromosome 15 and human chromosome 22qter.

P79937	MEIS1_XENLA	Homeobox protein Meis1	11960001	Xpbx1b and Xmeis1b play a collaborative role in hindbrain and neural crest gene expression in Xenopus embryos.

Q99567	NUP88_HUMAN	Nuclear pore complex protein Nup88	9049309	The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and the novel nuclear pore component Nup88.

O59679	GEF3_SCHPO	Rho guanine nucleotide exchange factor gef3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q7JVE7	R1AP1_DROME	RAG1-activating protein 1 homolog	9739134	saliva, a new Drosophila gene expressed in the embryonic salivary glands with homologues in plants and vertebrates.

P06766	DPOLB_RAT	DNA polymerase beta	11330999	Insight into the catalytic mechanism of DNA polymerase beta: structures of intermediate complexes.

P13798	ACPH_HUMAN	Acylamino-acid-releasing enzyme	2006156	Genetic relationship between acylpeptide hydrolase and acylase, two hydrolytic enzymes with similar binding but different catalytic specificities.

Q8WZ19	BACD1_HUMAN	BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1	19782033	Cullin mediates degradation of RhoA through evolutionarily conserved BTB adaptors to control actin cytoskeleton structure and cell movement.

Q12841	FSTL1_HUMAN	Follistatin-related protein 1	9786430	Cloning of follistatin-related protein as a novel autoantigen in systemic rheumatic diseases.

Q9D5U9	MICLK_MOUSE	MICAL C-terminal-like protein	18241670	Molecular cloning of Ebitein1: a novel extracellular signal-regulated kinase 2-binding protein in testis.

Q9HCK8	CHD8_HUMAN	Chromodomain-helicase-DNA-binding protein 8	15960975	Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

O95298	NDUC2_HUMAN	NADH dehydrogenase [ubiquinone] 1 subunit C2	9878551	cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed.

O14158	YE76_SCHPO	AB hydrolase superfamily protein C4A8.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O15342	VA0E1_HUMAN	V-type proton ATPase subunit e 1	17350184	Molecular cloning and characterization of a novel form of the human vacuolar H+-ATPase e-subunit: an essential proton pump component.

P03891	NU2M_HUMAN	NADH-ubiquinone oxidoreductase chain 2	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

P29674	LHX1_XENLA	LIM/homeobox protein Lhx1	8793615	The LIM homeodomain protein Lim-1 is widely expressed in neural, neural crest and mesoderm derivatives in vertebrate development.

Q80VJ2	SRA1_MOUSE	Steroid receptor RNA activator 1	15327771	Regulation of nuclear receptor activity by a pseudouridine synthase through posttranscriptional modification of steroid receptor RNA activator.

Q9W7F2	WDR1A_XENLA	WD repeat-containing protein 1-A	10212149	XAIP1: a Xenopus homologue of yeast actin interacting protein 1 (AIP1), which induces disassembly of actin filaments cooperatively with ADF/cofilin family proteins.

P25101	EDNRA_HUMAN	Endothelin-1 receptor	1326535	Organization, structure, chromosomal assignment, and expression of the gene encoding the human endothelin-A receptor.

O09053	WRN_MOUSE	Werner syndrome ATP-dependent helicase homolog	10757812	Mutations in the WRN Gene in mice accelerate mortality in a p53-null background.

O75323	NIPS2_HUMAN	Protein NipSnap homolog 2	9615231	GBAS, a novel gene encoding a protein with tyrosine phosphorylation sites and a transmembrane domain, is co-amplified with EGFR.

P39940	RSP5_YEAST	E3 ubiquitin-protein ligase RSP5	17213653	Peculiar protein-protein interactions of the novel endoplasmic reticulum membrane protein Rcr1 and ubiquitin ligase Rsp5.

O81058	ASK19_ARATH	SKP1-like protein 19	19682297	An F-box gene, CPR30, functions as a negative regulator of the defense response in Arabidopsis.

P55332	XYNA_EMENI	Endo-1,4-beta-xylanase A	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

P83178	HCYB_CARMA	Hemocyanin subunit B	2620501	The relationship between N-terminal sequences and immunological characterization of crustacean hemocyanins.

Q9YGL1	SPD1B_XENLA	Speedy protein 1-B	10465793	A novel p34cdc2 binding and activating protein that is necessary and sufficient to trigger G2/M progression in Xenopus oocytes.

P47037	SMC3_YEAST	Structural maintenance of chromosomes protein 3	9990856	Yeast cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication.

P13365	CG13_YEAST	G1/S-specific cyclin CLN3	3062366	DAF1, a mutant gene affecting size control, pheromone arrest, and cell cycle kinetics of Saccharomyces cerevisiae.

Q2PYN8	LBX1_XENLA	Transcription factor LBX1	16339190	A novel role for lbx1 in Xenopus hypaxial myogenesis.

Q24478	CP190_DROME	Centrosome-associated zinc finger protein CP190	8491775	Drosophila gamma-tubulin is part of a complex containing two previously identified centrosomal MAPs.

Q5VYV7	CT094_HUMAN	UPF0492 protein C20orf94	19596235	Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair.

P78545	ELF3_HUMAN	ETS-related transcription factor Elf-3	14715662	ESE-1 is a novel transcriptional mediator of angiopoietin-1 expression in the setting of inflammation.

P46676	SUM1_YEAST	Suppressor of mar1-1 protein	8754829	SUM1-1, a dominant suppressor of SIR mutations in Saccharomyces cerevisiae, increases transcriptional silencing at telomeres and HM mating-type loci and decreases chromosome stability.

O15354	GPR37_HUMAN	Probable G-protein coupled receptor 37	9144577	A novel endothelin receptor type-B-like gene enriched in the brain.

Q8IW41	MAPK5_HUMAN	MAP kinase-activated protein kinase 5	9628874	PRAK, a novel protein kinase regulated by the p38 MAP kinase.

Q9LXD8	HEC3_ARATH	Transcription factor HEC3	17855426	The HECATE genes regulate female reproductive tract development in Arabidopsis thaliana.

Q9Y3D2	MSRB2_HUMAN	Methionine-R-sulfoxide reductase B2, mitochondrial	10375640	Identification, expression and chromosome localization of a human gene encoding a novel protein with similarity to the pilB family of transcriptional factors (pilin) and to bacterial peptide methionine sulfoxide reductases.

Q6WBX8	RAD9B_HUMAN	Cell cycle checkpoint control protein RAD9B	14500360	Expression of mammalian paralogues of HRAD9 and Mrad9 checkpoint control genes in normal and cancerous testicular tissue.

O82485	OPT7_ARATH	Oligopeptide transporter 7	11788749	An oligopeptide transporter gene family in Arabidopsis.

P32458	CDC11_YEAST	Cell division control protein 11	12665577	Molecular dissection of a yeast septin: distinct domains are required for septin interaction, localization, and function.

Q9UBD9	CLCF1_HUMAN	Cardiotrophin-like cytokine factor 1	10500198	Novel neurotrophin-1/B cell-stimulating factor-3: a cytokine of the IL-6 family.

P0A9C9	GLPX_ECOLI	Fructose-1,6-bisphosphatase class 2	10986273	Purification and characterization of glpX-encoded fructose 1, 6- bisphosphatase, a new enzyme of the glycerol 3-phosphate regulon of Escherichia coli.

Q01827	VMAT2_RAT	Synaptic vesicular amine transporter	1438304	Expression cloning of a reserpine-sensitive vesicular monoamine transporter.

Q8L5U0	CSN4_ARATH	COP9 signalosome complex subunit 4	12615944	Characterization of the last subunit of the Arabidopsis COP9 signalosome: implications for the overall structure and origin of the complex.

Q9VPT1	GR21A_DROME	Gustatory and odorant receptor 21a	17167414	Two chemosensory receptors together mediate carbon dioxide detection in Drosophila.

Q9NRY5	F1142_HUMAN	Protein FAM114A2	10843801	Transcription mapping of the 5q- syndrome critical region: cloning of two novel genes and sequencing, expression, and mapping of a further six novel cDNAs.

P34223	UBX1_YEAST	UBX domain-containing protein 1	14562095	Global analysis of protein localization in budding yeast.

Q9MAM3	KCS1_ARATH	3-ketoacyl-CoA synthase 1	10074711	KCS1 encodes a fatty acid elongase 3-ketoacyl-CoA synthase affecting wax biosynthesis in Arabidopsis thaliana.

P50277	BIOA_YEAST	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	10333520	Characterization of the biotin biosynthesis pathway in Saccharomyces cerevisiae and evidence for a cluster containing BIO5, a novel gene involved in vitamer uptake.

Q8N3V7	SYNPO_HUMAN	Synaptopodin	18596123	KIBRA modulates directional migration of podocytes.

Q9LW26	Y3684_ARATH	Acyltransferase-like protein At3g26840, chloroplastic	16461379	Protein profiling of plastoglobules in chloroplasts and chromoplasts. A surprising site for differential accumulation of metabolic enzymes.

P38302	NTC20_YEAST	Pre-mRNA-splicing factor NTC20	11842115	Functional and physical interactions between components of the Prp19p-associated complex.

O95159	ZFPL1_HUMAN	Zinc finger protein-like 1	9653652	A putative human zinc-finger gene (ZFPL1) on 11q13, highly conserved in the mouse and expressed in exocrine pancreas.

P38314	SDS24_YEAST	Protein SDS24	16041152	Functional conservation between fission yeast moc1/sds23 and its two orthologs, budding yeast SDS23 and SDS24, and phenotypic differences in their disruptants.

Q61016	GBG7_MOUSE	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7	12488442	Loss of G protein gamma 7 alters behavior and reduces striatal alpha(olf) level and cAMP production.

Q9FQ09	KU80_ARATH	ATP-dependent DNA helicase 2 subunit KU80	16396834	A conserved and species-specific functional interaction between the Werner syndrome-like exonuclease atWEX and the Ku heterodimer in Arabidopsis.

P04002	ANPA_PSEAM	Ice-structuring protein A	1738160	Energy-optimized structure of antifreeze protein and its binding mechanism.

Q80XB4	NRAP_MOUSE	Nebulin-related-anchoring protein	11732910	Ultrastructural and biochemical localization of N-RAP at the interface between myofibrils and intercalated disks in the mouse heart.

P51841	GUC2F_HUMAN	Retinal guanylyl cyclase 2	7777544	Cloning and expression of a second photoreceptor-specific membrane retina guanylyl cyclase (RetGC), RetGC-2.

O60832	DKC1_HUMAN	H/ACA ribonucleoprotein complex subunit 4	10556300	Dyskerin localizes to the nucleolus and its mislocalization is unlikely to play a role in the pathogenesis of dyskeratosis congenita.

Q86XP1	DGKH_HUMAN	Diacylglycerol kinase eta	12810723	Identification and characterization of two splice variants of human diacylglycerol kinase eta.

Q64663	P2RX7_RAT	P2X purinoceptor 7	8614837	The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7).

Q06210	GFPT1_HUMAN	Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1	1460020	Molecular cloning, cDNA sequence, and bacterial expression of human glutamine:fructose-6-phosphate amidotransferase.

Q8AYG3	TTK_DANRE	Dual specificity protein kinase Ttk	12399306	Mps1 defines a proximal blastemal proliferative compartment essential for zebrafish fin regeneration.

Q04206	TF65_HUMAN	Transcription factor p65	16452207	Activation of the nuclear factor kappaB pathway by astrocyte elevated gene-1: implications for tumor progression and metastasis.

P81408	F189B_HUMAN	Protein FAM189B	15064722	WWOX binds the specific proline-rich ligand PPXY: identification of candidate interacting proteins.

P38988	YHM1_YEAST	Putative mitochondrial carrier protein YHM1/SHM1	8905928	SHM1: a multicopy suppressor of a temperature-sensitive null mutation in the HMG1-like abf2 gene.

Q9C6I6	ETFA_ARATH	Electron transfer flavoprotein subunit alpha, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P60212	SC48A_TITCA	Alpha-toxin Tc48a	15025998	Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

P78352	DLG4_HUMAN	Disks large homolog 4	7477295	Clustering of Shaker-type K+ channels by interaction with a family of membrane-associated guanylate kinases.

P06634	DED1_YEAST	ATP-dependent RNA helicase DED1	10364207	Ded1p, a DEAD-box protein required for translation initiation in Saccharomyces cerevisiae, is an RNA helicase.

P26640	SYVC_HUMAN	Valyl-tRNA synthetase	8428657	Cloning, sequencing and expression of a cDNA encoding mammalian valyl-tRNA synthetase.

Q94ID1	IPT7_ARATH	Adenylate isopentenyltransferase 7, mitochondrial	15998742	Agrobacterium tumefaciens increases cytokinin production in plastids by modifying the biosynthetic pathway in the host plant.

Q9GZP9	DERL2_HUMAN	Derlin-2	11500051	Cloning and characterization of F-LANa, upregulated in human liver cancer.

Q10360	RRN10_SCHPO	RNA polymerase I-specific transcription initiation factor rrn10	12490702	Characterization of the fission yeast ribosomal DNA binding factor: components share homology with upstream activating factor and with SWI/SNF subunits.

Q13465	MDS1_HUMAN	MDS1 and EVI1 complex locus protein MDS1	8643684	Intergenic splicing of MDS1 and EVI1 occurs in normal tissues as well as in myeloid leukemia and produces a new member of the PR domain family.

Q8W575	CSN3_ARATH	COP9 signalosome complex subunit 3	12615944	Characterization of the last subunit of the Arabidopsis COP9 signalosome: implications for the overall structure and origin of the complex.

P40337	VHL_HUMAN	Von Hippel-Lindau disease tumor suppressor	11739384	Ubiquitination of a novel deubiquitinating enzyme requires direct binding to von Hippel-Lindau tumor suppressor protein.

Q08929	GUP2_YEAST	Glycerol uptake protein 2	10931309	GUP1 and its close homologue GUP2, encoding multimembrane-spanning proteins involved in active glycerol uptake in Saccharomyces cerevisiae.

P52960	PIP2_YEAST	Peroxisome proliferation transcriptional regulator	8972187	A complex containing two transcription factors regulates peroxisome proliferation and the coordinate induction of beta-oxidation enzymes in Saccharomyces cerevisiae.

Q54E04	VATM_DICDI	Vacuolar proton translocating ATPase 100 kDa subunit	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P48432	SOX2_MOUSE	Transcription factor SOX-2	8625802	A comparison of the properties of Sox-3 with Sry and two related genes, Sox-1 and Sox-2.

Q9Z104	HM20B_MOUSE	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related	10773667	HMG20A and HMG20B map to human chromosomes 15q24 and 19p13.3 and constitute a distinct class of HMG-box genes with ubiquitous expression.

Q9P6J5	YHD5_SCHPO	Uncharacterized permease C1683.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O35730	RING1_MOUSE	E3 ubiquitin-protein ligase RING1	9312051	Ring1A is a transcriptional repressor that interacts with the Polycomb-M33 protein and is expressed at rhombomere boundaries in the mouse hindbrain.

Q9SYT0	ANXD1_ARATH	Annexin D1	15161963	Proteomic identification of annexins, calcium-dependent membrane binding proteins that mediate osmotic stress and abscisic acid signal transduction in Arabidopsis.

Q09704	RRP4_SCHPO	Exosome complex component rrp4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P54350	WEE1_DROME	Wee1-like protein kinase	8573790	Drosophila Wee1 kinase rescues fission yeast from mitotic catastrophe and phosphorylates Drosophila Cdc2 in vitro.

P93025	PHOT2_ARATH	Phototropin-2	18585389	Structural basis of the LOV1 dimerization of Arabidopsis phototropins 1 and 2.

O17468	HIRA_DROME	Protein HIRA homolog	10837127	The maternal effect mutation sesame affects the formation of the male pronucleus in Drosophila melanogaster.

Q8VD75	HIP1_MOUSE	Huntingtin-interacting protein 1	17329427	NMDA receptor function and NMDA receptor-dependent phosphorylation of huntingtin is altered by the endocytic protein HIP1.

P24903	CP2F1_HUMAN	Cytochrome P450 2F1	10383923	Specific dehydrogenation of 3-methylindole and epoxidation of naphthalene by recombinant human CYP2F1 expressed in lymphoblastoid cells.

P38827	SET1_YEAST	Histone-lysine N-methyltransferase, H3 lysine-4 specific	12845608	Saccharomyces cerevisiae Set1p is a methyltransferase specific for lysine 4 of histone H3 and is required for efficient gene expression.

Q9H6X2	ANTR1_HUMAN	Anthrax toxin receptor 1	16762926	Anthrax toxin receptor 1/tumor endothelium marker 8 mediates cell spreading by coupling extracellular ligands to the actin cytoskeleton.

Q9BZI7	REN3B_HUMAN	Regulator of nonsense transcripts 3B	11163187	Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon.

P63115	AAA1_MOUSE	Asc-type amino acid transporter 1	10734121	Identification and characterization of a Na+-independent neutral amino acid transporter that associates with the 4F2 heavy chain and exhibits substrate selectivity for small neutral D- and L- amino acids.

O22152	YAB1_ARATH	Axial regulator YABBY 1	10331982	The Arabidopsis FILAMENTOUS FLOWER gene is required for flower formation.

Q969G9	NKD1_HUMAN	Protein naked cuticle homolog 1	16567647	PR130 is a modulator of the Wnt-signaling cascade that counters repression of the antagonist Naked cuticle.

P18835	COL19_CAEEL	Cuticle collagen 19	2753356	Sequence comparisons of developmentally regulated collagen genes of Caenorhabditis elegans.

O48737	TRXM1_ARATH	Thioredoxin M1, chloroplastic	19259774	A novel extended family of stromal thioredoxins.

Q99417	MYCBP_HUMAN	C-Myc-binding protein	12151104	AMAP-1, a novel testis-specific AMY-1-binding protein, is differentially expressed during the course of spermatogenesis.

Q9P0J6	RM36_HUMAN	39S ribosomal protein L36, mitochondrial	11279069	Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria.

Q9Z2E5	ATOH7_MOUSE	Protein atonal homolog 7	12451142	Loss of photic entrainment and altered free-running circadian rhythms in math5-/- mice.

P39980	SIT1_YEAST	Siderophore iron transporter 1	9884238	Siderophore-mediated iron uptake in Saccharomyces cerevisiae: the SIT1 gene encodes a ferrioxamine B permease that belongs to the major facilitator superfamily.

P43614	KEG1_YEAST	Beta-1,6-glucan synthesis-associated protein KEG1	17893149	KEG1/YFR042w encodes a novel Kre6-binding endoplasmic reticulum membrane protein responsible for beta-1,6-glucan synthesis in Saccharomyces cerevisiae.

P77173	ZIPA_ECOLI	Cell division protein zipA	9008158	Direct binding of FtsZ to ZipA, an essential component of the septal ring structure that mediates cell division in E. coli.

P56915	GSC_HUMAN	Homeobox protein goosecoid	7916327	Molecular cloning of the human homeobox gene goosecoid (GSC) and mapping of the gene to human chromosome 14q32.1.

Q24434	ORD_DROME	Protein ORD	12062057	The sister-chromatid cohesion protein ORD is required for chiasma maintenance in Drosophila oocytes.

P58909	LECA_DIOVO	Lectin alpha chain	10082964	Molecular characterization and crystallization of Diocleinae lectins.

P35193	ATG19_YEAST	Autophagy-related protein 19	11382752	Yol082p, a novel CVT protein involved in the selective targeting of aminopeptidase I to the yeast vacuole.

Q9JLB9	PVRL3_MOUSE	Poliovirus receptor-related protein 3	10744716	Nectin-3: a new member of immunoglobulin-like cell adhesion molecules that shows homophilic and heterophilic cell-cell adhesion activities.

Q9VVU5	CSN1_DROME	COP9 signalosome complex subunit 1b	12737805	The COP9 signalosome promotes degradation of Cyclin E during early Drosophila oogenesis.

Q9FLG2	MRS22_ARATH	Magnesium transporter MRS2-2	19966073	A root-expressed magnesium transporter of the MRS2/MGT gene family in Arabidopsis thaliana allows for growth in low-Mg2+ environments.

P63056	NOE3_MOUSE	Noelin-3	12019210	Optimedin: a novel olfactomedin-related protein that interacts with myocilin.

Q9V3I5	JIL1_DROME	Chromosomal serine/threonine-protein kinase JIL-1	12538650	A developmentally regulated splice variant from the complex lola locus encoding multiple different zinc finger domain proteins interacts with the chromosomal kinase JIL-1.

Q04110	ECM11_YEAST	Protein ECM11	9335584	Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae.

Q5WA50	CTR2_OCTVU	Cephalotocin receptor 2	15504101	Novel evolutionary lineages of the invertebrate oxytocin/vasopressin superfamily peptides and their receptors in the common octopus (Octopus vulgaris).

P21775	THIKA_RAT	3-ketoacyl-CoA thiolase A, peroxisomal	2307679	Rat peroxisomal 3-ketoacyl-CoA thiolase gene. Occurrence of two closely related but differentially regulated genes.

Q9Y800	MUG97_SCHPO	Meiotically up-regulated gene 97 protein	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

P36952	SPB5_HUMAN	Serpin B5	16049006	Mammary serine protease inhibitor (Maspin) binds directly to interferon regulatory factor 6: identification of a novel serpin partnership.

O13772	HUA1_SCHPO	Proline/serine-rich protein C17A5.10	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O01346	EGH_DROME	Beta-1,4-mannosyltransferase egh	9012507	The neurogenic genes egghead and brainiac define a novel signaling pathway essential for epithelial morphogenesis during Drosophila oogenesis.

Q9VP05	MED1_DROME	Mediator of RNA polymerase II transcription subunit 1	16751183	Coactivator cross-talk specifies transcriptional output.

P02461	CO3A1_HUMAN	Collagen alpha-1(III) chain	7487954	Abnormal type III collagen produced by an exon-17-skipping mutation of the COL3A1 gene in Ehlers-Danlos syndrome type IV is not incorporated into the extracellular matrix.

Q03096	EST3_YEAST	Telomere replication protein EST3	16884717	Saccharomyces cerevisiae telomerase subunit Est3p binds DNA and RNA and stimulates unwinding of RNA/DNA heteroduplexes.

Q6B2C0	MTAL2_YEAST	Mating-type protein ALPHA2	3893743	A repressor (MAT alpha 2 Product) and its operator control expression of a set of cell type specific genes in yeast.

O80925	AGD7_ARATH	ADP-ribosylation factor GTPase-activating protein AGD7	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

Q9JL10	SRTD1_MOUSE	SERTA domain-containing protein 1	11331592	TRIP-Br: a novel family of PHD zinc finger- and bromodomain- interacting proteins that regulate the transcriptional activity of E2F-1/DP-1.

Q874R3	APC2_SCHPO	Anaphase-promoting complex subunit 2	12477395	Proteomics analysis identifies new components of the fission and budding yeast anaphase-promoting complexes.

O75691	UTP20_HUMAN	Small subunit processome component 20 homolog	16458307	Mapping nucleolar localization sequences of 1A6/DRIM.

Q8H191	PAO4_ARATH	Probable polyamine oxidase 4	18703589	A putative peroxisomal polyamine oxidase, AtPAO4, is involved in polyamine catabolism in Arabidopsis thaliana.

Q9H0K1	SIK2_HUMAN	Serine/threonine-protein kinase SIK2	14976552	LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1.

O81445	CNBL1_ARATH	Calcineurin B-like protein 1	17922773	Two calcineurin B-like calcium sensors, interacting with protein kinase CIPK23, regulate leaf transpiration and root potassium uptake in Arabidopsis.

P39517	DHH1_YEAST	ATP-dependent RNA helicase DHH1	9504907	Dhh1p, a putative RNA helicase, associates with the general transcription factors Pop2p and Ccr4p from Saccharomyces cerevisiae.

Q9HBU1	BARX1_HUMAN	Homeobox protein BarH-like 1	10995576	Cloning, characterization, localization, and mutational screening of the human BARX1 gene.

Q80UE6	WNK4_MOUSE	Serine/threonine-protein kinase WNK4	12515852	Molecular pathogenesis of inherited hypertension with hyperkalemia: The Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4.

Q9SM23	ACBP1_ARATH	Acyl-CoA-binding domain-containing protein 1	18182029	Overexpression of membrane-associated acyl-CoA-binding protein ACBP1 enhances lead tolerance in Arabidopsis.

Q09897	CHR3_SCHPO	Chitin synthase regulatory factor 3	15449309	Chr4, a Schizosaccharomyces pombe homologue of the Saccharomyces cerevisiae Chs4p/Skt5p protein, is related to septum formation and is required for the proper localization of Chs2.

P53397	OGG1_YEAST	N-glycosylase/DNA lyase	8643552	Cloning and expression in Escherichia coli of the OGG1 gene of Saccharomyces cerevisiae, which codes for a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N- methylformamidopyrimidine.

Q00604	NDP_HUMAN	Norrin	8252044	A mutation in the Norrie disease gene (NDP) associated with X-linked familial exudative vitreoretinopathy.

P83851	IUNH_LEIMA	Inosine-uridine preferring nucleoside hydrolase	10409664	Nucleoside hydrolase from Leishmania major. Cloning, expression, catalytic properties, transition state inhibitors, and the 2.5-A crystal structure.

Q9LI74	CHUP1_ARATH	Protein CHUP1, chloroplastic	18715957	Chloroplast outer envelope protein CHUP1 is essential for chloroplast anchorage to the plasma membrane and chloroplast movement.

Q8R2H7	TRAK2_RAT	Trafficking kinesin-binding protein 2	12435728	Identification and cloning of a novel family of coiled-coil domain proteins that interact with O-GlcNAc transferase.

Q03429	FMP36_YEAST	Protein FMP36, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P06634	DED1_YEAST	ATP-dependent RNA helicase DED1	16216083	ATP- and ADP-dependent modulation of RNA unwinding and strand annealing activities by the DEAD-box protein DED1.

Q8N726	CD2A2_HUMAN	Cyclin-dependent kinase inhibitor 2A, isoform 4	15989956	ARF-BP1/Mule is a critical mediator of the ARF tumor suppressor.

P37303	GLY1_YEAST	Low specificity L-threonine aldolase	9151955	The GLY1 gene of Saccharomyces cerevisiae encodes a low-specific L- threonine aldolase that catalyzes cleavage of L-allo-threonine and L- threonine to glycine -- expression of the gene in Escherichia coli and purification and characterization of the enzyme.

O93937	PYR1_EMENI	Protein pyrABCN	10417650	Structural and transcriptional analysis of the pyrABCN, pyrD and pyrF genes in Aspergillus nidulans and the evolutionary origin of fungal dihydroorotases.

Q9W4S7	MYC_DROME	Myc protein	17311883	The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth.

O59667	HIS2_SCHPO	Histidine biosynthesis bifunctional protein his7	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P0AEP9	GLCD_ECOLI	Glycolate oxidase subunit glcD	8606183	glc locus of Escherichia coli: characterization of genes encoding the subunits of glycolate oxidase and the glc regulator protein.

P34529	DCR1_CAEEL	Endoribonuclease dcr-1	11641272	Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans.

P27715	UNC13_CAEEL	Phorbol ester/diacylglycerol-binding protein unc-13	11029047	Expression of multiple UNC-13 proteins in the Caenorhabditis elegans nervous system.

P37702	BGL38_ARATH	Myrosinase 1	15643972	Nucleotide variation at the myrosinase-encoding locus, TGG1, and quantitative myrosinase enzyme activity variation in Arabidopsis thaliana.

Q96PD2	DCBD2_HUMAN	Discoidin, CUB and LCCL domain-containing protein 2	11447234	ESDN, a novel neuropilin-like membrane protein cloned from vascular cells with the longest secretory signal sequence among eukaryotes, is up-regulated after vascular injury.

O59932	GHT4_SCHPO	High-affinity hexose transporter ght4	10735857	Multiple hexose transporters of Schizosaccharomyces pombe.

Q9QY14	FOXE3_MOUSE	Forkhead box protein E3	10652278	A forkhead gene, FoxE3, is essential for lens epithelial proliferation and closure of the lens vesicle.

Q13216	ERCC8_HUMAN	DNA excision repair protein ERCC-8	16916636	Cockayne syndrome A and B proteins differentially regulate recruitment of chromatin remodeling and repair factors to stalled RNA polymerase II in vivo.

Q9P2R7	SUCB1_HUMAN	Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial	10727444	Interaction between succinyl CoA synthetase and the heme-biosynthetic enzyme ALAS-E is disrupted in sideroblastic anemia.

Q9VFK6	SETD8_DROME	Histone-lysine N-methyltransferase pr-set7	12121615	Purification and functional characterization of SET8, a nucleosomal histone H4-lysine 20-specific methyltransferase.

P32600	TOR2_YEAST	Serine/threonine-protein kinase TOR2	8846782	FKBP12-rapamycin target TOR2 is a vacuolar protein with an associated phosphatidylinositol-4 kinase activity.

Q6Q546	HUB1_YEAST	Ubiquitin-like modifier HUB1	11923536	Role of a ubiquitin-like modification in polarized morphogenesis.

P32479	HIR1_YEAST	Protein HIR1	16303565	Replication-independent histone deposition by the HIR complex and Asf1.

Q7Z569	BRAP_HUMAN	BRCA1-associated protein	14724641	Ras regulates assembly of mitogenic signalling complexes through the effector protein IMP.

Q9C9W9	ADO3_ARATH	Adagio protein 3	15310821	Identification of ASK and clock-associated proteins as molecular partners of LKP2 (LOV kelch protein 2) in Arabidopsis.

P37398	VIV_ORYSJ	B3 domain-containing protein VP1	11917085	Temporal and spatial expression pattern of the OSVP1 and OSEM genes during seed development in rice.

Q9Y6G5	COMDA_HUMAN	COMM domain-containing protein 10	15799966	COMMD proteins, a novel family of structural and functional homologs of MURR1.

Q8R4I7	NETO1_MOUSE	Neuropilin and tolloid-like protein 1	19243221	Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning.

Q9NS67	GPR27_HUMAN	Probable G-protein coupled receptor 27	10833454	An evolutionarily conserved G-protein coupled receptor family, SREB, expressed in the central nervous system.

Q27257	DIF1_CAEEL	Protein dif-1	7774589	Embryonic tissue differentiation in Caenorhabditis elegans requires dif-1, a gene homologous to mitochondrial solute carriers.

Q92900	RENT1_HUMAN	Regulator of nonsense transcripts 1	12554878	Characterization of human Smg5/7a: a protein with similarities to Caenorhabditis elegans SMG5 and SMG7 that functions in the dephosphorylation of Upf1.

O93870	FCR1_CANAL	Fluconazole resistance protein 1	9864335	Isolation of a putative Candida albicans transcriptional regulator involved in pleiotropic drug resistance by functional complementation of a pdr1 pdr3 mutation in Saccharomyces cerevisiae.

Q13418	ILK_HUMAN	Integrin-linked protein kinase	8538749	Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase.

Q7M767	UB2V2_RAT	Ubiquitin-conjugating enzyme E2 variant 2	12750002	Identification of numerous genes differentially expressed in rat brain during postnatal development by suppression subtractive hybridization and expression analysis of the novel rat gene rMMS2.

P84213	BOMB_BOMVA	Bombesin	15134346	Skin secretion of the toad Bombina variegata contains multiple insulin-releasing peptides including bombesin and entirely novel insulinotropic structures.

P00492	HPRT_HUMAN	Hypoxanthine-guanine phosphoribosyltransferase	6300847	Isolation and characterization of a full-length expressible cDNA for human hypoxanthine phosphoribosyl transferase.

Q9FKM5	XRCC3_ARATH	DNA repair protein XRCC3 homolog	12139010	Molecular cloning and characterization of RAD51-like genes from Arabidopsis thaliana.

Q39212	RPB3B_ARATH	DNA-directed RNA polymerase II subunit RPB3-B	16489121	Arabidopsis GLUTAMINE-RICH PROTEIN23 is essential for early embryogenesis and encodes a novel nuclear PPR motif protein that interacts with RNA polymerase II subunit III.

Q10197	ALP1_SCHPO	Tubulin-folding cofactor D	9450991	Essential role of tubulin-folding cofactor D in microtubule assembly and its association with microtubules in fission yeast.

P13010	XRCC5_HUMAN	X-ray repair cross-complementing protein 5	20383123	Ku is a 5'-dRP/AP lyase that excises nucleotide damage near broken ends.

P86292	CADF1_PLAFX	Cofilin/actin-depolymerizing factor homolog 1	15975905	A Plasmodium actin-depolymerizing factor that binds exclusively to actin monomers.

Q9C7F7	UGPI5_ARATH	Uncharacterized GPI-anchored protein At1g27950	12805588	Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis.

Q9VZF4	FBXW7_DROME	F-box/WD repeat-containing protein 7	11565033	Archipelago regulates cyclin E levels in Drosophila and is mutated in human cancer cell lines.

Q92207	HOG1_CANAL	Mitogen-activated protein kinase HOG1	10322006	Role of the mitogen-activated protein kinase Hog1p in morphogenesis and virulence of Candida albicans.

P33448	TOM6_YEAST	Mitochondrial import receptor subunit TOM6	9774667	Preprotein translocase of the outer mitochondrial membrane: molecular dissection and assembly of the general import pore complex.

O74942	CYP9_SCHPO	Peptidyl-prolyl cis-trans isomerase 9	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P21521	SY65_DROME	Synaptotagmin 1	11069931	The products of the Drosophila stoned locus interact with synaptic vesicles via synaptotagmin.

Q8I0P1	SPAST_DROME	Spastin	17452528	Three microtubule severing enzymes contribute to the 'Pacman-flux' machinery that moves chromosomes.

Q9UNA3	A4GCT_HUMAN	Alpha-1,4-N-acetylglucosaminyltransferase	10430883	Expression cloning of a human alpha1, 4-N- acetylglucosaminyltransferase that forms GlcNAcalpha1-->4Galbeta-->R, a glycan specifically expressed in the gastric gland mucous cell-type mucin.

O60099	YOX2_SCHPO	Uncharacterized protein C14F5.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P23899	HNF1B_RAT	Hepatocyte nuclear factor 1-beta	1673926	vHNF1 is a homeoprotein that activates transcription and forms heterodimers with HNF1.

Q9H2D6	TARA_HUMAN	TRIO and F-actin-binding protein	18194665	The E3 ubiquitin ligase HECTD3 regulates ubiquitination and degradation of Tara.

P52298	NCBP2_HUMAN	Nuclear cap-binding protein subunit 2	11551508	Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20.

P25374	NFS1_YEAST	Cysteine desulfurase, mitochondrial	10406803	The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins.

P15424	MS116_YEAST	ATP-dependent RNA helicase MSS116, mitochondrial	2535893	Mitochondrial splicing requires a protein from a novel helicase family.

Q9NTN3	S35D1_HUMAN	UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter	11322953	Molecular characterization of human UDP-glucuronic acid/UDP-N- acetylgalactosamine transporter, a novel nucleotide sugar transporter with dual substrate specificity.

Q9UKL6	PPCT_HUMAN	Phosphatidylcholine transfer protein	12055623	Structure of human phosphatidylcholine transfer protein in complex with its ligand.

Q99935	PROL1_HUMAN	Proline-rich protein 1	17101991	Human opiorphin, a natural antinociceptive modulator of opioid- dependent pathways.

P08138	TNR16_HUMAN	Tumor necrosis factor receptor superfamily member 16	3022937	Expression and structure of the human NGF receptor.

Q9BRQ5	ORAI3_HUMAN	Protein orai-3	20418871	A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cells.

P54269	CAUP_DROME	Homeobox protein caupolican	8620542	Araucan and caupolican, two members of the novel iroquois complex, encode homeoproteins that control proneural and vein-forming genes.

P09588	H2A_CAEEL	Histone H2A	2544730	Nucleotide sequences of Caenorhabditis elegans core histone genes. Genes for different histone classes share common flanking sequence elements.

Q03100	CYAA_DICDI	Adenylate cyclase, aggregation specific	15821137	Intracellular role of adenylyl cyclase in regulation of lateral pseudopod formation during Dictyostelium chemotaxis.

P83243	KA131_TITCA	Potassium channel toxin alpha-KTx 13.1	11113450	Tc1, from Tityus cambridgei, is the first member of a new subfamily of scorpion toxin that blocks K(+)-channels.

Q64240	AMBP_RAT	Protein AMBP	1371936	Rat alpha 1-microglobulin: co-expression in liver with the light chain of inter-alpha-trypsin inhibitor.

Q02793	SKI8_YEAST	Antiviral protein SKI8	10744028	The yeast antiviral proteins Ski2p, Ski3p, and Ski8p exist as a complex in vivo.

Q7Z020	TRPA1_DROME	Transient receptor potential cation channel subfamily A member 1	12815418	Ion channels: opposite thermosensor in fruitfly and mouse.

P14778	IL1R1_HUMAN	Interleukin-1 receptor type 1	9062193	Crystal structure of the type-I interleukin-1 receptor complexed with interleukin-1beta.

Q6PH37	ST1S1_DANRE	Cytosolic sulfotransferase 1	12755695	Sulfation of hydroxychlorobiphenyls. Molecular cloning, expression, and functional characterization of zebrafish SULT1 sulfotransferases.

Q9P3A8	CAND1_SCHPO	Cullin-associated NEDD8-dissociated protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P36860	RALB_RAT	Ras-related protein Ral-B	16382162	RalB mobilizes the exocyst to drive cell migration.

Q9V3H2	PSDE_DROME	26S proteasome non-ATPase regulatory subunit 14	10893261	The regulatory complex of Drosophila melanogaster 26S proteasomes. Subunit composition and localization of a deubiquitylating enzyme.

P47820	ACE_RAT	Angiotensin-converting enzyme	8292044	Angiotensin converting enzyme and genetic hypertension: cloning of rat cDNAs and characterization of the enzyme.

Q6P9Q6	FKB15_MOUSE	FK506-binding protein 15	16756961	FKBP133: a novel mouse FK506-binding protein homolog alters growth cone morphology.

P42345	MTOR_HUMAN	Serine/threonine-protein kinase mTOR	12408816	Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control.

Q12071	VPS54_YEAST	Vacuolar protein sorting-associated protein 54	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q5PQX1	TOIP1_RAT	Torsin-1A-interacting protein 1	7721789	cDNA cloning and characterization of lamina-associated polypeptide 1C (LAP1C), an integral protein of the inner nuclear membrane.

Q61955	KLK8_MOUSE	Kallikrein-8	17182622	Kallikrein 8 is involved in skin desquamation in cooperation with other kallikreins.

P31930	QCR1_HUMAN	Cytochrome b-c1 complex subunit 1, mitochondrial	8407948	Complete coding sequence, intron/exon organization, and chromosomal location of the gene for the core I protein of human ubiquinol- cytochrome c reductase.

O08808	DIAP1_MOUSE	Protein diaphanous homolog 1	14992721	The core FH2 domain of diaphanous-related formins is an elongated actin binding protein that inhibits polymerization.

Q18825	BAR1_CAEEL	Beta-catenin/armadillo-related protein 1	9716532	The beta-catenin homolog BAR-1 and LET-60 Ras coordinately regulate the Hox gene lin-39 during Caenorhabditis elegans vulval development.

Q94F62	BAK1_ARATH	BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1	15548744	Heterodimerization and endocytosis of Arabidopsis brassinosteroid receptors BRI1 and AtSERK3 (BAK1).

P41772	AMT1_CANGA	Metal-activated transcriptional activator protein AMT1	9665167	Solution structure of a zinc domain conserved in yeast copper- regulated transcription factors.

P32927	IL3RB_HUMAN	Cytokine receptor common subunit beta	9410898	Human pulmonary alveolar proteinosis associated with a defect in GM- CSF/IL-3/IL-5 receptor common beta chain expression.

P81450	ATP18_YEAST	ATP synthase subunit J, mitochondrial	9867878	Isolation of supernumerary yeast ATP synthase subunits e and i. Characterization of subunit i and disruption of its structural gene ATP18.

O35409	FOLH1_MOUSE	Glutamate carboxypeptidase 2	11210180	Cloning, expression, genomic localization, and enzymatic activities of the mouse homolog of prostate-specific membrane antigen/NAALADase/ folate hydrolase.

Q96R27	OR2M4_HUMAN	Olfactory receptor 2M4	9119360	Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species.

P62651	ERI1_YEAST	Phosphatidylinositol N-acetylglucosaminyltransferase ERI1 subunit	15163411	Yeast Ras regulates the complex that catalyzes the first step in GPI- anchor biosynthesis at the ER.

Q9Y7T4	ATG1_SCHPO	Serine/threonine-protein kinase atg1	15821139	Systematic deletion analysis of fission yeast protein kinases.

Q9VLK4	DIUX_DROME	Diuretic hormone class 2	11316500	The Drosophila melanogaster homologue of an insect calcitonin-like diuretic peptide stimulates V-ATPase activity in fruit fly Malpighian tubules.

Q08I43	ERI1_SCHPO	3'-5' exonuclease eri1	16797182	Conserved ribonuclease, Eri1, negatively regulates heterochromatin assembly in fission yeast.

B0YJ81	HACD1_HUMAN	3-hydroxyacyl-CoA dehydratase 1	10644438	Molecular cloning, chromosomal mapping, and developmental expression of a novel protein tyrosine phosphatase-like gene.

Q9FHM4	MA653_ARATH	65-kDa microtubule-associated protein 3	12226511	Two new loci, PLEIADE and HYADE, implicate organ-specific regulation of cytokinesis in Arabidopsis.

P47040	BTN1_YEAST	Protein BTN1	9753630	The subcellular location of the yeast Saccharomyces homologue of the protein defective in the juvenile form of Batten disease.

P32910	RPC6_YEAST	DNA-directed RNA polymerase III subunit RPC6	1400451	An essential and specific subunit of RNA polymerase III (C) is encoded by gene RPC34 in Saccharomyces cerevisiae.

Q9BZR9	TRIM8_HUMAN	Probable E3 ubiquitin-protein ligase TRIM8	11331580	The tripartite motif family identifies cell compartments.

P81909	OR22A_DROME	Odorant receptor 22a	10069338	A novel family of divergent seven-transmembrane proteins: candidate odorant receptors in Drosophila.

Q42374	SY111_ARATH	Syntaxin-related protein KNOLLE	11157980	The cytokinesis gene KEULE encodes a Sec1 protein that binds the syntaxin KNOLLE.

O54880	RPH3L_RAT	Rab effector Noc2	9367993	Noc2, a putative zinc finger protein involved in exocytosis in endocrine cells.

Q5H9S7	DCA17_HUMAN	DDB1- and CUL4-associated factor 17	16949367	A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1.

Q16584	M3K11_HUMAN	Mitogen-activated protein kinase kinase kinase 11	8183572	MLK-3: identification of a widely-expressed protein kinase bearing an SH3 domain and a leucine zipper-basic region domain.

Q96EE3	SEH1_HUMAN	Nucleoporin SEH1	15146057	The entire Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis.

P53697	MNN9_CANAL	Mannan polymerase complex subunit MNN9	10601199	Molecular analysis of the Candida albicans homolog of Saccharomyces cerevisiae MNN9, required for glycosylation of cell wall mannoproteins.

Q9HGM8	KU80_SCHPO	ATP-dependent DNA helicase II subunit 2	12424244	Telomeric DNA ends are essential for the localization of Ku at telomeres in fission yeast.

P58956	G39AA_DROME	Putative gustatory receptor 39a, isoform B	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

Q9UST3	VPS52_SCHPO	Vacuolar protein sorting-associated protein 52	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q7LL04	YQK1_SCHPO	UPF0676 protein C1494.01	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q08553	SYC1_YEAST	Protein SYC1	12819204	Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-ends.

Q8CJ52	PROM2_RAT	Prominin-2	12446606	Identification and characterization of a novel testosterone-regulated prominin-like gene in the rat ventral prostate.

Q9UTS5	ZAS1_SCHPO	Zinc finger protein zas1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O88312	AGR2_MOUSE	Anterior gradient protein 2 homolog	19359471	The protein disulfide isomerase AGR2 is essential for production of intestinal mucus.

Q9UHB6	LIMA1_HUMAN	LIM domain and actin-binding protein 1	11256614	Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.

Q9UEE5	ST17A_HUMAN	Serine/threonine-protein kinase 17A	9786912	DRAKs, novel serine/threonine kinases related to death-associated protein kinase that trigger apoptosis.

Q5HYK7	SH319_HUMAN	SH3 domain-containing protein 19	15280379	ADAM binding protein Eve-1 is required for ectodomain shedding of epidermal growth factor receptor ligands.

Q94B60	CLPP4_ARATH	ATP-dependent Clp protease proteolytic subunit 4, chloroplastic	14593120	Clp protease complexes from photosynthetic and non-photosynthetic plastids and mitochondria of plants, their predicted three-dimensional structures, and functional implications.

P36056	RT22_YEAST	37S ribosomal protein S22, mitochondrial	11278769	Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues.

P54652	HSP72_HUMAN	Heat shock-related 70 kDa protein 2	7829106	Cloning, sequencing, and mapping of the human chromosome 14 heat shock protein gene (HSPA2).

Q9VQU9	BOWEL_DROME	Protein bowel	8670819	Bowel, an odd-skipped homolog, functions in the terminal pathway during Drosophila embryogenesis.

Q9UUI5	SEC24_SCHPO	Protein transport protein sec24	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O00241	SIRB1_HUMAN	Signal-regulatory protein beta-1	9062191	A family of proteins that inhibit signalling through tyrosine kinase receptors.

Q5PQX0	UXS1_RAT	UDP-glucuronic acid decarboxylase 1	11877387	UDP-glucuronate decarboxylase, a key enzyme in proteoglycan synthesis. Cloning, characterization, and localization.

Q9VL78	FKB59_DROME	FK506-binding protein 59	11514552	Regulation of Drosophila TRPL channels by immunophilin FKBP59.

P40976	LYS2_SCHPO	L-aminoadipate-semialdehyde dehydrogenase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O88551	CLD1_MOUSE	Claudin-1	10562289	Manner of interaction of heterogeneous claudin species within and between tight junction strands.

P40318	DOA10_YEAST	ERAD-associated E3 ubiquitin-protein ligase DOA10	11641273	A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Matalpha2 repressor degradation.

P51668	UB2D1_HUMAN	Ubiquitin-conjugating enzyme E2 D1	18845142	The autoantigen Ro52 is an E3 ligase resident in the cytoplasm but enters the nucleus upon cellular exposure to nitric oxide.

P07948	LYN_HUMAN	Tyrosine-protein kinase Lyn	11306681	Molecular cloning, genomic positioning, promoter identification, and characterization of the novel cyclic AMP-specific phosphodiesterase PDE4A10.

Q3E7A4	YB059_YEAST	Coiled-coil-helix-coiled-coil-helix domain-containing protein YBL059C-A	14562095	Global analysis of protein localization in budding yeast.

Q9U298	ACH8_CAEEL	Neuronal acetylcholine receptor subunit eat-2	15020415	eat-2 and eat-18 are required for nicotinic neurotransmission in the Caenorhabditis elegans pharynx.

Q8R1H0	HOP_MOUSE	Homeodomain-only protein	12975471	Cardiac hypertrophy and histone deacetylase-dependent transcriptional repression mediated by the atypical homeodomain protein Hop.

Q95RV2	CAV_DROME	Telomere-binding protein cav	19190990	Umbrea, a chromo shadow domain protein in Drosophila melanogaster heterochromatin, interacts with Hip, HP1 and HOAP.

Q13547	HDAC1_HUMAN	Histone deacetylase 1	10898795	BCoR, a novel corepressor involved in BCL-6 repression.

Q0JXE7	BPE_ARATH	Transcription factor BPE	16902407	BIGPETALp, a bHLH transcription factor is involved in the control of Arabidopsis petal size.

Q14160	SCRIB_HUMAN	Protein scribble homolog	15775968	Thyrotropin receptor trafficking relies on the hScrib-betaPIX-GIT1- ARF6 pathway.

Q9NY46	SCN3A_HUMAN	Sodium channel protein type 3 subunit alpha	9589372	Isolation of a human-brain sodium-channel gene encoding two isoforms of the subtype III alpha-subunit.

P27932	AMY3A_ORYSJ	Alpha-amylase isozyme 3A	1714318	Characterization of an alpha-amylase multigene cluster in rice.

P40531	GVP36_YEAST	Protein GVP36	16107716	Immunoisolaton of the yeast Golgi subcompartments and characterization of a novel membrane protein, Svp26, discovered in the Sed5-containing compartments.

Q9VJE5	CL190_DROME	Restin homolog	9472041	A class VI unconventional myosin is associated with a homologue of a microtubule-binding protein, cytoplasmic linker protein-170, in neurons and at the posterior pole of Drosophila embryos.

Q24180	DEAF1_DROME	Deformed epidermal autoregulatory factor 1	8617243	DEAF-1, a novel protein that binds an essential region in a Deformed response element.

P36402	TCF7_HUMAN	Transcription factor 7	1569101	The human T cell transcription factor-1 gene. Structure, localization, and promoter characterization.

P38689	KPR3_YEAST	Ribose-phosphate pyrophosphokinase 3	15280369	Heterooligomeric phosphoribosyl diphosphate synthase of Saccharomyces cerevisiae: combinatorial expression of the five PRS genes in Escherichia coli.

O14262	YFP5_SCHPO	Putative uncharacterized hydrolase C7D4.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8R4H4	CBPA5_MOUSE	Carboxypeptidase A5	11836249	Identification and characterization of three members of the human metallocarboxypeptidase gene family.

P15151	PVR_HUMAN	Poliovirus receptor	2538245	Cellular receptor for poliovirus: molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulin superfamily.

O42930	PEP1_SCHPO	Vacuolar protein sorting/targeting protein pep1	16622069	Vacuolar protein sorting receptor in Schizosaccharomyces pombe.

Q8WUX1	S38A5_HUMAN	Sodium-coupled neutral amino acid transporter 5	11243884	Structure, function, and tissue expression pattern of human SN2, a subtype of the amino acid transport system N.

P42951	LSB6_YEAST	Phosphatidylinositol 4-kinase LSB6	12523934	Saccharomyces cerevisiae contains a Type II phosphoinositide 4- kinase.

P10080	SSBP1_YEAST	Single-stranded nucleic acid-binding protein	16782896	Sbp1p affects translational repression and decapping in Saccharomyces cerevisiae.

Q4VCS5	AMOT_HUMAN	Angiomotin	11257124	Angiomotin. An angiostatin binding protein that regulates endothelial cell migration and tube formation.

Q3KQ35	S17AA_XENLA	Transcription factor Sox-17-alpha-A	11124113	Maternal VegT is the initiator of a molecular network specifying endoderm in Xenopus laevis.

Q12348	CSN10_YEAST	COP9 signalosome complex subunit 10	12186635	Conservation of the COP9/signalosome in budding yeast.

P08100	OPSD_HUMAN	Rhodopsin	19934218	A dual role for EDEM1 in the processing of rod opsin.

P78329	CP4F2_HUMAN	Leukotriene-B(4) omega-hydroxylase 1	8026587	Cloning and expression of a novel form of leukotriene B4 omega- hydroxylase from human liver.

Q8VHT6	AS3MT_RAT	Arsenite methyltransferase	11790780	A novel S-adenosyl-L-methionine:arsenic(III) methyltransferase from rat liver cytosol.

Q9FHW7	SKP1B_ARATH	SKP1-like protein 1B	18036202	SKP2A, an F-box protein that regulates cell division, is degraded via the ubiquitin pathway.

Q15274	NADC_HUMAN	Nicotinate-nucleotide pyrophosphorylase [carboxylating]	17868694	Structural and kinetic characterization of quinolinate phosphoribosyltransferase (hQPRTase) from homo sapiens.

P47190	PMT3_YEAST	Dolichyl-phosphate-mannose--protein mannosyltransferase 3	8585318	PMT3 and PMT4, two new members of the protein-O-mannosyltransferase gene family of Saccharomyces cerevisiae.

Q9Y4A5	TRRAP_HUMAN	Transformation/transcription domain-associated protein	10373431	Identification of TATA-binding protein-free TAFII-containing complex subunits suggests a role in nucleosome acetylation and signal transduction.

Q43127	GLNA2_ARATH	Glutamine synthetase, chloroplastic/mitochondrial	1684022	The glutamine synthetase gene family of Arabidopsis thaliana: light- regulation and differential expression in leaves, roots and seeds.

Q96AQ7	CIDEC_HUMAN	Cell death activator CIDE-3	12429024	Molecular cloning and characterization of CIDE-3, a novel member of the cell-death-inducing DNA-fragmentation-factor (DFF45)-like effector family.

Q940J1	ATB16_ARATH	Homeobox-leucine zipper protein ATHB-16	14623244	The Arabidopsis homeobox gene, ATHB16, regulates leaf development and the sensitivity to photoperiod in Arabidopsis.

P97357	TAF1A_MOUSE	TATA box-binding protein-associated factor RNA polymerase I subunit A	9050847	Cloning of murine RNA polymerase I-specific TAF factors: conserved interactions between the subunits of the species-specific transcription initiation factor TIF-IB/SL1.

P69490	CCME_ECOLI	Cytochrome c-type biogenesis protein CcmE	11744735	A bacterial cytochrome c heme lyase. CcmF forms a complex with the heme chaperone CcmE and CcmH but not with apocytochrome c.

Q9Y262	EIF3L_HUMAN	Eukaryotic translation initiation factor 3 subunit L	17322308	Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry.

P87125	URED_SCHPO	Uncharacterized urease accessory protein ureD-like	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P00175	CYB2_YEAST	Cytochrome b2, mitochondrial	3004948	Structure, expression and regulation of a nuclear gene encoding a mitochondrial protein: the yeast L(+)-lactate cytochrome c oxidoreductase (cytochrome b2).

O62618	MK14A_DROME	Mitogen-activated protein kinase 14A	9584193	A conserved p38 mitogen-activated protein kinase pathway regulates Drosophila immunity gene expression.

Q04759	KPCT_HUMAN	Protein kinase C theta type	8444877	Molecular cloning and characterization of PKC theta, a novel member of the protein kinase C (PKC) gene family expressed predominantly in hematopoietic cells.

Q8WUY3	PRUN2_HUMAN	Protein prune homolog 2	16288218	Increased expression of proapoptotic BMCC1, a novel gene with the BNIP2 and Cdc42GAP homology (BCH) domain, is associated with favorable prognosis in human neuroblastomas.

Q96FV9	THOC1_HUMAN	THO complex subunit 1	15358532	The death domain protein p84N5, but not the short isoform p84N5s, is cell cycle-regulated and shuttles between the nucleus and the cytoplasm.

Q9XZ58	CSN5_DROME	COP9 signalosome complex subunit 5	12032852	The TRC8 hereditary kidney cancer gene suppresses growth and functions with VHL in a common pathway.

Q9Y286	SIGL7_HUMAN	Sialic acid-binding Ig-like lectin 7	10567377	Identification and characterization of a novel siglec, siglec-7, expressed by human natural killer cells and monocytes.

Q92207	HOG1_CANAL	Mitogen-activated protein kinase HOG1	8824643	The mitogen-activated protein kinase homolog HOG1 gene controls glycerol accumulation in the pathogenic fungus Candida albicans.

P23945	FSHR_HUMAN	Follicle-stimulating hormone receptor	7553856	Mutation in the follicle-stimulating hormone receptor gene causes hereditary hypergonadotropic ovarian failure.

O88492	PLIN4_MOUSE	Perilipin-4	9624692	Cloning of cell-specific secreted and surface proteins by subtractive antibody screening.

P0AB77	KBL_ECOLI	2-amino-3-ketobutyrate coenzyme A ligase	3117785	Purification, properties, and N-terminal amino acid sequence of homogeneous Escherichia coli 2-amino-3-ketobutyrate CoA ligase, a pyridoxal phosphate-dependent enzyme.

Q8C6B9	AROS_MOUSE	Active regulator of SIRT1	16289379	A novel nucleolar protein interacts with ribosomal protein S19.

P62259	1433E_MOUSE	14-3-3 protein epsilon	12796778	14-3-3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome.

O74627	CG1C_SCHPO	Cyclin pch1	9115279	pch1(+), a second essential C-type cyclin gene in Schizosaccharomyces pombe.

Q9QVC8	FKBP4_RAT	Peptidyl-prolyl cis-trans isomerase FKBP4	20133804	A role for FKBP52 in Tau protein function.

P45562	XAPB_ECOLI	Xanthosine permease	7559336	Identification and characterization of genes (xapA, xapB, and xapR) involved in xanthosine catabolism in Escherichia coli.

Q9FLE8	Y5986_ARATH	Uncharacterized protein At5g39865	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q9MA41	CTL1_ARATH	Chitinase-like protein 1	9165126	Structural and genetic analysis of epidermal cell differentiation in Arabidopsis primary roots.

P23946	CMA1_HUMAN	Chymase	8144971	Determination of the primary structures of human skin chymase and cathepsin G from cutaneous mast cells of urticaria pigmentosa lesions.

O08759	UBE3A_MOUSE	Ubiquitin-protein ligase E3A	9182527	Subcellular localization and ubiquitin-conjugating enzyme (E2) interactions of mammalian HECT family ubiquitin protein ligases.

P41138	ID3_RAT	DNA-binding protein inhibitor ID-3	7908517	Activation of helix-loop-helix proteins Id1, Id2 and Id3 during neural differentiation.

Q924A5	S36A1_RAT	Proton-coupled amino acid transporter 1	12598615	The H+-coupled electrogenic lysosomal amino acid transporter LYAAT1 localizes to the axon and plasma membrane of hippocampal neurons.

P18754	RCC1_HUMAN	Regulator of chromosome condensation	1944575	Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1.

P34470	HCP3_CAEEL	Histone H3-like centromeric protein hcp-3	11402065	Functional analysis of kinetochore assembly in Caenorhabditis elegans.

Q9HFE1	FET4_SCHPO	Low-affinity iron/zinc ion transport protein fet4	18203864	Response of Schizosaccharomyces pombe to zinc deficiency.

Q61187	TS101_MOUSE	Tumor susceptibility gene 101 protein	10888872	DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci.

P49407	ARRB1_HUMAN	Beta-arrestin-1	15611106	beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation.

P38170	CND2_YEAST	Condensin complex subunit 2	10811823	The condensin complex governs chromosome condensation and mitotic transmission of rDNA.

Q15269	PWP2_HUMAN	Periodic tryptophan protein 2 homolog	8661145	Cloning the cDNA of human PWP2, which encodes a protein with WD repeats and maps to 21q22.3.

P51142	DVL2_XENLA	Segment polarity protein dishevelled homolog DVL-2	11493574	Xenopus Dishevelled signaling regulates both neural and mesodermal convergent extension: parallel forces elongating the body axis.

Q04311	YD049_YEAST	Zinc finger protein YDR049W	14562095	Global analysis of protein localization in budding yeast.

P19112	F16P1_RAT	Fructose-1,6-bisphosphatase 1	2847161	cDNA sequence of rat liver fructose-1,6-bisphosphatase and evidence for down-regulation of its mRNA by insulin.

P63033	RHES_RAT	GTP-binding protein Rhes	19498170	Rhes, a striatal specific protein, mediates mutant-huntingtin cytotoxicity.

Q4KUS2	UN13A_MOUSE	Protein unc-13 homolog A	19996097	Fbxo45, a novel ubiquitin ligase, regulates synaptic activity.

P28319	CWP1_YEAST	Cell wall protein CWP1	7768807	Identification of three mannoproteins in the cell wall of Saccharomyces cerevisiae.

Q9W706	FXF1A_XENLA	Forkhead box protein F1-A	15656969	Of fox and frogs: fox (fork head/winged helix) transcription factors in Xenopus development.

O95954	FTCD_HUMAN	Formimidoyltransferase-cyclodeaminase	10029623	Formiminotransferase cyclodeaminase is an organ-specific autoantigen recognized by sera of patients with autoimmune hepatitis.

P48755	FOSL1_MOUSE	Fos-related antigen 1	9294610	Structure and chromosomal assignment of the mouse fra-1 gene, and its exclusion as a candidate gene for oc (osteosclerosis).

Q12328	TIM22_YEAST	Mitochondrial import inner membrane translocase subunit TIM22	8955274	Import of carrier proteins into the mitochondrial inner membrane mediated by Tim22.

P36662	TORD_ECOLI	Chaperone protein torD	9632735	TorD, a cytoplasmic chaperone that interacts with the unfolded trimethylamine N-oxide reductase enzyme (TorA) in Escherichia coli.

P25123	GBRB_DROME	Gamma-aminobutyric acid receptor subunit beta	8016117	Cloning and functional expression of a Drosophila gamma-aminobutyric acid receptor.

Q12734	CSR2_YEAST	Transcription factor CSR2	12444972	Molecular characterization of MRG19 of Saccharomyces cerevisiae. Implication in the regulation of galactose and nonfermentable carbon source utilization.

Q9S7Z3	PCS1_ARATH	Glutathione gamma-glutamylcysteinyltransferase 1	10368185	Phytochelatin synthase genes from Arabidopsis and the yeast Schizosaccharomyces pombe.

Q9UUJ0	PVG5_SCHPO	Pyruvylated Gal-beta-1,3-epitope synthesis protein 5	15173185	Five genes involved in biosynthesis of the pyruvylated Galbeta1,3- epitope in Schizosaccharomyces pombe N-linked glycans.

P54296	MYOM2_HUMAN	Myomesin-2	7505783	The globular head domain of titin extends into the center of the sarcomeric M band. cDNA cloning, epitope mapping and immunoelectron microscopy of two titin-associated proteins.

Q9GLW0	PRGR_CANFA	Progesterone receptor	11282275	Cloning and cellular localization of the canine progesterone receptor: co-localization with growth hormone in the mammary gland.

P23771	GATA3_HUMAN	Trans-acting T-cell-specific transcription factor GATA-3	10935639	GATA3 haplo-insufficiency causes human HDR syndrome.

P32600	TOR2_YEAST	Serine/threonine-protein kinase TOR2	12631735	Tor kinases are in distinct membrane-associated protein complexes in Saccharomyces cerevisiae.

Q94AG2	SERK1_ARATH	Somatic embryogenesis receptor kinase 1	16284305	The Arabidopsis thaliana SOMATIC EMBRYOGENESIS RECEPTOR-LIKE KINASES1 and 2 control male sporogenesis.

Q04767	TVP18_YEAST	Golgi apparatus membrane protein TVP18	17178117	Tvp38, Tvp23, Tvp18 and Tvp15: novel membrane proteins in the Tlg2- containing Golgi/endosome compartments of Saccharomyces cerevisiae.

Q9H313	TTYH1_HUMAN	Protein tweety homolog 1	10950931	Human and mouse homologues of the Drosophila melanogaster tweety (tty) gene: a novel gene family encoding predicted transmembrane proteins.

P43626	KI2L1_HUMAN	Killer cell immunoglobulin-like receptor 2DL1	18604210	An essential function for beta-arrestin 2 in the inhibitory signaling of natural killer cells.

Q9SJH7	CISY3_ARATH	Citrate synthase 3, peroxisomal	15923350	Arabidopsis peroxisomal citrate synthase is required for fatty acid respiration and seed germination.

P21757	MSRE_HUMAN	Macrophage scavenger receptor types I and II	8093617	Structure, organization, and chromosomal mapping of the human macrophage scavenger receptor gene.

Q13185	CBX3_HUMAN	Chromobox protein homolog 3	10330177	KAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: a potential role for Kruppel-associated box-zinc finger proteins in heterochromatin- mediated gene silencing.

O60148	YNSI_SCHPO	Uncharacterized membrane protein C18H10.18c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P41738	AHR_RAT	Aryl hydrocarbon receptor	9658193	Point mutation in intron sequence causes altered carboxyl-terminal structure in the aryl hydrocarbon receptor of the most 2,3,7,8- tetrachlorodibenzo-p-dioxin-resistant rat strain.

Q6PQK2	NP7_RHOPR	Nitrophorin-7	15170336	Recognition of anionic phospholipid membranes by an antihemostatic protein from a blood-feeding insect.

P10070	GLI2_HUMAN	Zinc finger protein GLI2	15994174	A previously unidentified amino-terminal domain regulates transcriptional activity of wild-type and disease-associated human GLI2.

P04001	OPSG_HUMAN	Green-sensitive opsin	2937147	Molecular genetics of human color vision: the genes encoding blue, green, and red pigments.

Q02455	MLP1_YEAST	Protein MLP1	12531921	The C-terminal domain of myosin-like protein 1 (Mlp1p) is a docking site for heterogeneous nuclear ribonucleoproteins that are required for mRNA export.

Q8VBU8	BANP_MOUSE	Protein BANP	10940556	Identification and molecular analysis of BANP.

P53226	BUD9_YEAST	Bud site selection protein 9	11514631	Bud8p and Bud9p, proteins that may mark the sites for bipolar budding in yeast.

C0LGG9	Y5344_ARATH	Probable LRR receptor-like serine/threonine-protein kinase At1g53440	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q02759	LX12L_RAT	Arachidonate 12-lipoxygenase, leukocyte-type	8117750	Arachidonate 12-lipoxygenase of rat pineal glands: catalytic properties and primary structure deduced from its cDNA.

Q13951	PEBB_HUMAN	Core-binding factor subunit beta	10856244	Structural basis for the heterodimeric interaction between the acute leukaemia-associated transcription factors AML1 and CBFbeta.

O14261	TAF1_SCHPO	Taz1-interacting factor 1	11270572	Schizosaccharomyces pombe taf1+ is required for nitrogen starvation- induced sexual development and for entering the dormant GO state.

Q9H6K4	OPA3_HUMAN	Optic atrophy 3 protein	11668429	Type III 3-methylglutaconic aciduria (optic atrophy plus syndrome, or Costeff optic atrophy syndrome): identification of the OPA3 gene and its founder mutation in Iraqi Jews.

P13207	EDN3_RAT	Endothelin-3	1378731	Cloning and expression of rat preproendothelin-3 cDNA.

P34998	CRFR1_HUMAN	Corticotropin-releasing factor receptor 1	10598591	A novel spliced variant of the type 1 corticotropin-releasing hormone receptor with a deletion in the seventh transmembrane domain present in the human pregnant term myometrium and fetal membranes.

Q8AXX8	SOX10_XENLA	Transcription factor Sox-10	16256735	SoxE factors function equivalently during neural crest and inner ear development and their activity is regulated by SUMOylation.

P39984	HAT2_YEAST	Histone acetyltransferase type B subunit 2	10982821	Type B histone acetyltransferase Hat1p participates in telomeric silencing.

Q1AGV7	SDC4A_XENLA	Syndecan 4-A	16604063	Syndecan-4 regulates non-canonical Wnt signalling and is essential for convergent and extension movements in Xenopus embryos.

Q9V719	SIN1_DROME	Stress-activated map kinase-interacting protein 1	16919458	mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s.

O14305	SID1_SCHPO	Serine/threonine-protein kinase sid1	11384993	Interaction between the noncatalytic region of Sid1p kinase and Cdc14p is required for full catalytic activity and localization of Sid1p.

P38555	YPT31_YEAST	GTP-binding protein YPT31/YPT8	11785952	Saccharomyces cerevisiae Pra1p/Yip3p interacts with Yip1p and Rab proteins.

Q96S65	CSRN1_HUMAN	Cysteine/serine-rich nuclear protein 1	11526492	Identification of AXUD1, a novel human gene induced by AXIN1 and its reduced expression in human carcinomas of the lung, liver, colon and kidney.

Q8IID4	DYHC2_PLAF7	Dynein heavy chain-like protein PF11_0240	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

Q9R0C0	PLDN_MOUSE	Pallidin	10610180	The pallid gene encodes a novel, syntaxin 13-interacting protein involved in platelet storage pool deficiency.

P23497	SP100_HUMAN	Nuclear autoantigen Sp-100	9636146	Interaction of SP100 with HP1 proteins: a link between the promyelocytic leukemia-associated nuclear bodies and the chromatin compartment.

P07320	CRGD_HUMAN	Gamma-crystallin D	9927684	Progressive juvenile-onset punctate cataracts caused by mutation of the gamma-D-crystallin gene.

Q9H3R5	CENPH_HUMAN	Centromere protein H	11092768	Human CENP-H multimers colocalize with CENP-A and CENP-C at active centromere-kinetochore complexes.

Q8CBW3	ABI1_MOUSE	Abl interactor 1	12672821	Abl interactor 1 promotes tyrosine 296 phosphorylation of mammalian enabled (Mena) by c-Abl kinase.

Q9JK11	RTN4_RAT	Reticulon-4	19665976	A class of dynamin-like GTPases involved in the generation of the tubular ER network.

Q9FK43	SIP12_ARATH	Probable aquaporin SIP1-2	16223486	Novel type aquaporin SIPs are mainly localized to the ER membrane and show cell-specific expression in Arabidopsis thaliana.

Q86B87	MMD4_DROME	Modifier of mdg4	11024164	Functional studies of the BTB domain in the Drosophila GAGA and Mod(mdg4) proteins.

P62491	RB11A_HUMAN	Ras-related protein Rab-11A	17007872	Structural basis for Rab11-mediated recruitment of FIP3 to recycling endosomes.

P32485	HOG1_YEAST	Mitogen-activated protein kinase HOG1	10817757	Two protein tyrosine phosphatases, Ptp2 and Ptp3, modulate the subcellular localization of the Hog1 MAP kinase in yeast.

Q04947	RTN1_YEAST	Reticulon-like protein 1	14562095	Global analysis of protein localization in budding yeast.

O18209	PMY13_CAEEL	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase wee-1.3	16338136	The C. elegans DYRK Kinase MBK-2 marks oocyte proteins for degradation in response to meiotic maturation.

Q6UK63	PIRA_DICDI	Protein pirA	12956949	PIR121 regulates pseudopod dynamics and SCAR activity in Dictyostelium.

P07271	PIF1_YEAST	DNA repair and recombination protein PIF1	1849081	PIF1: a DNA helicase in yeast mitochondria.

Q96EA4	SPDLY_HUMAN	Protein Spindly	19468067	Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly.

P30556	AGTR1_HUMAN	Type-1 angiotensin II receptor	16116425	Mutations in genes in the renin-angiotensin system are associated with autosomal recessive renal tubular dysgenesis.

P32798	COT1_YEAST	Cobalt uptake protein COT1	1508175	COT1, a gene involved in cobalt accumulation in Saccharomyces cerevisiae.

P87060	POP1_SCHPO	WD repeat-containing protein pop1	9203581	Fission yeast WD-repeat protein pop1 regulates genome ploidy through ubiquitin-proteasome-mediated degradation of the CDK inhibitor Rum1 and the S-phase initiator Cdc18.

Q13285	STF1_HUMAN	Steroidogenic factor 1	17664281	Cyclic AMP-stimulated interaction between steroidogenic factor 1 and diacylglycerol kinase theta facilitates induction of CYP17.

P53330	RT102_YEAST	Regulator of Ty1 transposition protein 102	14562095	Global analysis of protein localization in budding yeast.

P61073	CXCR4_HUMAN	C-X-C chemokine receptor type 4	10644702	beta-arrestin differentially regulates the chemokine receptor CXCR4- mediated signaling and receptor internalization, and this implicates multiple interaction sites between beta-arrestin and CXCR4.

P43601	ATG18_YEAST	Autophagy-related protein 18	19037259	VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P(2) in yeast and mouse.

O43708	MAAI_HUMAN	Maleylacetoacetate isomerase	9396740	Zeta, a novel class of glutathione transferases in a range of species from plants to humans.

Q6PDM2	SRSF1_MOUSE	Serine/arginine-rich splicing factor 1	15652482	ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle.

Q4G3H4	IKKA_DANRE	Inhibitor of nuclear factor kappa-B kinase subunit alpha	16051172	Zebrafish IkappaB kinase 1 negatively regulates NF-kappaB activity.

Q969V6	MKL1_HUMAN	MKL/myocardin-like protein 1	19350017	SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta1-integrin.

Q8VYU6	GOGC4_ARATH	Golgin candidate 4	18182439	Localization and domain characterization of Arabidopsis golgin candidates.

Q9FY74	CMTA1_ARATH	Calmodulin-binding transcription activator 1	11782485	Genes encoding calmodulin-binding proteins in the Arabidopsis genome.

Q9UMX0	UBQL1_HUMAN	Ubiquilin-1	11853878	Characterization of ubiquilin 1, an mTOR-interacting protein.

Q03148	SNZ1_YEAST	Pyridoxine biosynthesis protein SNZ1	9791124	The highly conserved, coregulated SNO and SNZ gene families in Saccharomyces cerevisiae respond to nutrient limitation.

P11226	MBL2_HUMAN	Mannose-binding protein C	1304173	High frequencies in African and non-African populations of independent mutations in the mannose binding protein gene.

Q9V460	SPT5H_DROME	Transcription elongation factor SPT5	11040217	High-resolution localization of Drosophila Spt5 and Spt6 at heat shock genes in vivo: roles in promoter proximal pausing and transcription elongation.

Q99678	GPR20_HUMAN	G-protein coupled receptor 20	18347022	Characterization of an orphan G protein-coupled receptor, GPR20, that constitutively activates Gi proteins.

P04551	CDK1_SCHPO	Cell division control protein 2	8455610	Two fission yeast B-type cyclins, cig2 and Cdc13, have different functions in mitosis.

P42282	TTKA_DROME	Protein tramtrack, alpha isoform	15306652	A conserved role but different partners for the transcriptional corepressor CoREST in fly and mammalian nervous system formation.

Q8H1R4	AB10I_ARATH	ABC transporter I family member 10, chloroplastic	12938931	Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis.

P92201	LCP8_DROME	Larval cuticle protein 8	9654737	Identification of proteins and developmental expression of RNAs encoded by the 65A cuticle protein gene cluster in Drosophila melanogaster.

Q9XI60	LPP2_ARATH	Lipid phosphate phosphatase 2	11278556	Lipid phosphate phosphatases in Arabidopsis. Regulation of the AtLPP1 gene in response to stress.

O75410	TACC1_HUMAN	Transforming acidic coiled-coil-containing protein 1	11903063	Interaction of the transforming acidic coiled-coil 1 (TACC1) protein with ch-TOG and GAS41/NuBI1 suggests multiple TACC1-containing protein complexes in human cells.

Q9H2F3	3BHS7_HUMAN	3 beta-hydroxysteroid dehydrogenase type 7	11067870	The bile acid synthetic gene 3beta-hydroxy-delta(5)-C(27)-steroid oxidoreductase is mutated in progressive intrahepatic cholestasis.

Q99MH5	NDK5_MOUSE	Nucleoside diphosphate kinase homolog 5	12788088	Cloning, sequencing, and characterization of the murine nm23-M5 gene during mouse spermatogenesis and spermiogenesis.

A7UFC2	TBPL1_ENTHI	TATA-box-binding protein-like protein 1	20026212	Entamoeba histolytica: a unicellular organism containing two active genes encoding for members of the TBP family.

O60888	CUTA_HUMAN	Protein CutA	10800960	Hydrophobic protein that copurifies with human brain acetylcholinesterase: amino acid sequence, genomic organization, and chromosomal localization.

Q08605	GAGA_DROME	Transcription factor GAGA	12384587	The Drosophila transcription factor tramtrack (TTK) interacts with Trithorax-like (GAGA) and represses GAGA-mediated activation.

Q9Y251	HPSE_HUMAN	Heparanase	10395325	Mammalian heparanase: gene cloning, expression and function in tumor progression and metastasis.

P15202	CATA_YEAST	Peroxisomal catalase A	9931255	Structure of catalase-A from Saccharomyces cerevisiae.

P34164	SIP2_YEAST	SNF1 protein kinase subunit beta-2	12393914	Purification and characterization of Snf1 kinase complexes containing a defined beta subunit composition.

Q16513	PKN2_HUMAN	Serine/threonine-protein kinase N2	7851406	Cloning and expression patterns of two members of a novel protein- kinase-C-related kinase family.

Q9V3R6	ADAT1_DROME	tRNA-specific adenosine deaminase 1	10629039	The properties of a tRNA-specific adenosine deaminase from Drosophila melanogaster support an evolutionary link between pre-mRNA editing and tRNA modification.

Q6ZHS4	CADH2_ORYSJ	Cinnamyl alcohol dehydrogenase 2	16443696	GOLD HULL AND INTERNODE2 encodes a primarily multifunctional cinnamyl-alcohol dehydrogenase in rice.

P53924	DMA2_YEAST	E3 ubiquitin-protein ligase DMA2	15146058	Functional characterization of Dma1 and Dma2, the budding yeast homologues of Schizosaccharomyces pombe Dma1 and human Chfr.

Q9Y2I2	NTNG1_HUMAN	Netrin-G1	14595443	The netrin-G1 ligand NGL-1 promotes the outgrowth of thalamocortical axons.

P27487	DPP4_HUMAN	Dipeptidyl peptidase 4	16651416	The protease complex consisting of dipeptidyl peptidase IV and seprase plays a role in the migration and invasion of human endothelial cells in collagenous matrices.

P17425	HMCS1_RAT	Hydroxymethylglutaryl-CoA synthase, cytoplasmic	1972979	Nucleotide sequence of a rat liver cDNA encoding the cytosolic 3- hydroxy-3-methylglutaryl coenzyme A synthase.

Q9Y6W6	DUS10_HUMAN	Dual specificity protein phosphatase 10	10391943	Molecular cloning and characterization of a novel dual specificity phosphatase, MKP-5.

Q39214	RPM1_ARATH	Disease resistance protein RPM1	16212605	A duplicated pair of Arabidopsis RING-finger E3 ligases contribute to the RPM1- and RPS2-mediated hypersensitive response.

Q94ID1	IPT7_ARATH	Adenylate isopentenyltransferase 7, mitochondrial	14726522	Distinct isoprenoid origins of cis- and trans-zeatin biosyntheses in Arabidopsis.

Q670P5	WNT11_XENLA	Protein Wnt-11	17240368	Wnt11-R signaling regulates a calcium sensitive EMT event essential for dorsal fin development of Xenopus.

Q9W4Y2	PDFR_DROME	PDF receptor	16242407	Drosophila GPCR Han is a receptor for the circadian clock neuropeptide PDF.

P62851	RS25_HUMAN	40S ribosomal protein S25	1748303	Cloning and sequencing a cDNA encoding human ribosomal protein S25.

Q9NVR5	KTU_HUMAN	Protein kintoun	19052621	Ktu/PF13 is required for cytoplasmic pre-assembly of axonemal dyneins.

P40030	ERG28_YEAST	Ergosterol biosynthetic protein 28	12119386	Protein-protein interactions among C-4 demethylation enzymes involved in yeast sterol biosynthesis.

P43487	RANG_HUMAN	Ran-specific GTPase-activating protein	7882974	Co-activation of RanGTPase and inhibition of GTP dissociation by Ran- GTP binding protein RanBP1.

Q93VD3	CIPKN_ARATH	CBL-interacting serine/threonine-protein kinase 23	17898163	A protein phosphorylation/dephosphorylation network regulates a plant potassium channel.

Q6XQN6	PNCB_HUMAN	Nicotinate phosphoribosyltransferase	17604275	Elevation of cellular NAD levels by nicotinic acid and involvement of nicotinic acid phosphoribosyltransferase in human cells.

Q9NP98	MYOZ1_HUMAN	Myozenin-1	11171996	Myozenin: an alpha-actinin- and gamma-filamin-binding protein of skeletal muscle Z lines.

O94410	MU163_SCHPO	Meiotically up-regulated gene 163 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O89040	PLCB2_RAT	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2	9860142	Identification of a phospholipase C beta subtype in rat taste cells.

O01761	UNC89_CAEEL	Muscle M-line assembly protein unc-89	15313609	Three new isoforms of Caenorhabditis elegans UNC-89 containing MLCK- like protein kinase domains.

Q9UHF7	TRPS1_HUMAN	Zinc finger transcription factor Trps1	10615131	Mutations in a new gene, encoding a zinc-finger protein, cause tricho-rhino-phalangeal syndrome type I.

Q13356	PPIL2_HUMAN	Peptidyl-prolyl cis-trans isomerase-like 2	8660300	Identification of a nuclear-specific cyclophilin which interacts with the proteinase inhibitor eglin c.

Q12168	ENG2_YEAST	Endo-1,3(4)-beta-glucanase 2	12455695	Eng1p, an endo-1,3-beta-glucanase localized at the daughter side of the septum, is involved in cell separation in Saccharomyces cerevisiae.

Q9FML4	LOB_ARATH	Protein LATERAL ORGAN BOUNDARIES	12068116	The LATERAL ORGAN BOUNDARIES gene defines a novel, plant-specific gene family.

P22749	GNLY_HUMAN	Granulysin	9756476	An antimicrobial activity of cytolytic T cells mediated by granulysin.

P11746	MCM1_YEAST	Pheromone receptor transcription factor	9490409	Crystal structure of the yeast MATalpha2/MCM1/DNA ternary complex.

P15265	MCSP_MOUSE	Sperm mitochondrial-associated cysteine-rich protein	8916043	Developmental expression, intracellular localization, and selenium content of the cysteine-rich protein associated with the mitochondrial capsules of mouse sperm.

Q96EP5	DAZP1_HUMAN	DAZ-associated protein 1	10857750	Identification of two novel proteins that interact with germ-cell- specific RNA-binding proteins DAZ and DAZL1.

P17967	PDI_YEAST	Protein disulfide-isomerase	16413482	The crystal structure of yeast protein disulfide isomerase suggests cooperativity between its active sites.

P34546	VATL2_CAEEL	V-type proton ATPase 16 kDa proteolipid subunit 2/3	9305897	Three vha genes encode proteolipids of Caenorhabditis elegans vacuolar-type ATPase. Gene structures and preferential expression in an H-shaped excretory cell and rectal cells.

P29459	IL12A_HUMAN	Interleukin-12 subunit alpha	1673147	Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells.

P20039	2B1B_HUMAN	HLA class II histocompatibility antigen, DRB1-11 beta chain	3456344	Complete characterization and sequence of an HLA class II DR beta chain cDNA from the DR5 haplotype.

Q55FW5	CUPA_DICDI	Calcium up-regulated protein A	14871937	The Ca2+/calcineurin-regulated cup gene family in Dictyostelium discoideum and its possible involvement in development.

Q8R4X1	ACER1_MOUSE	Alkaline ceramidase 1	12783875	Cloning and characterization of a mouse endoplasmic reticulum alkaline ceramidase: an enzyme that preferentially regulates metabolism of very long chain ceramides.

Q4V7G1	SKAP1_RAT	Src kinase-associated phosphoprotein 1	12681493	Targeting of MIST to Src-family kinases via SKAP55-SLAP-130 adaptor complex in mast cells(1).

O59833	YCUD_SCHPO	Uncharacterized transporter C965.13	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P40215	NDH1_YEAST	External NADH-ubiquinone oxidoreductase 1, mitochondrial	9696750	Identification of a cytosolically directed NADH dehydrogenase in mitochondria of Saccharomyces cerevisiae.

Q9Y561	LRP12_HUMAN	Low-density lipoprotein receptor-related protein 12	9927190	Cloning and characterization of a novel gene encoding a putative transmembrane protein with altered expression in some human transformed and tumor-derived cell lines.

Q969V5	MUL1_HUMAN	Mitochondrial ubiquitin ligase activator of NFKB 1	18207745	Cargo-selected transport from the mitochondria to peroxisomes is mediated by vesicular carriers.

Q12221	PUF2_YEAST	mRNA-binding protein PUF2	15024427	Extensive association of functionally and cytotopically related mRNAs with Puf family RNA-binding proteins in yeast.

Q9R803	SSED_SALTY	Secreted effector protein sseD	11567004	SseBCD proteins are secreted by the type III secretion system of Salmonella pathogenicity island 2 and function as a translocon.

O74519	YCPD_SCHPO	Uncharacterized N-acetyltransferase C663.13c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q14061	COX17_HUMAN	Cytochrome c oxidase copper chaperone	9050918	Isolation of a cDNA encoding the human homolog of COX17, a yeast gene essential for mitochondrial copper recruitment.

P32156	RHAM_ECOLI	L-rhamnose mutarotase	15060078	NMR application probes a novel and ubiquitous family of enzymes that alter monosaccharide configuration.

Q15262	PTPRK_HUMAN	Receptor-type tyrosine-protein phosphatase kappa	19167335	Large-scale structural analysis of the classical human protein tyrosine phosphatome.

P61224	RAP1B_HUMAN	Ras-related protein Rap-1b	2123345	Posttranslationally processed structure of the human platelet protein smg p21B: evidence for geranylgeranylation and carboxyl methylation of the C-terminal cysteine.

P84193	AUD_PHACH	Aldos-2-ulose dehydratase	15716041	Enzymatic description of the anhydrofructose pathway of glycogen degradation II. Gene identification and characterization of the reactions catalyzed by aldos-2-ulose dehydratase that converts 1,5- anhydro-d-fructose to microthecin with ascopyrone M as the intermediate.

O14617	AP3D1_HUMAN	AP-3 complex subunit delta-1	9303295	Altered expression of a novel adaptin leads to defective pigment granule biogenesis in the Drosophila eye color mutant garnet.

Q8AZK7	EBNA5_EBVB9	Epstein-Barr nuclear antigen leader protein	16177824	Mediation of Epstein-Barr virus EBNA-LP transcriptional coactivation by Sp100.

Q2YDF6	RT35_BOVIN	28S ribosomal protein S35, mitochondrial	11344316	Identification of four proteins from the small subunit of the mammalian mitochondrial ribosome using a proteomics approach.

Q6RZZ9	KIF13_DICDI	Kinesin-related protein 13	18712789	Kinesin-5 is not essential for mitotic spindle elongation in Dictyostelium.

O15537	XLRS1_HUMAN	Retinoschisin	9326935	Positional cloning of the gene associated with X-linked juvenile retinoschisis.

Q6KC79	NIPBL_HUMAN	Nipped-B-like protein	15146186	Cornelia de Lange syndrome is caused by mutations in NIPBL, the human homolog of Drosophila melanogaster Nipped-B.

Q9WV55	VAPA_MOUSE	Vesicle-associated membrane protein-associated protein A	10655491	Mouse VAP33 is associated with the endoplasmic reticulum and microtubules.

Q7L8A9	VASH1_HUMAN	Vasohibin-1	15467828	Vasohibin as an endothelium-derived negative feedback regulator of angiogenesis.

Q9Y2D9	ZN652_HUMAN	Zinc finger protein 652	16966434	ZNF652, a novel zinc finger protein, interacts with the putative breast tumor suppressor CBFA2T3 to repress transcription.

Q8LL04	CPL3_ARATH	RNA polymerase II C-terminal domain phosphatase-like 3	16905668	Arabidopsis carboxyl-terminal domain phosphatase-like isoforms share common catalytic and interaction domains but have distinct in planta functions.

P26263	PDC6_YEAST	Pyruvate decarboxylase isozyme 3	14562095	Global analysis of protein localization in budding yeast.

P0AFE4	NUOK_ECOLI	NADH-quinone oxidoreductase subunit K	15996109	Characterization of the membrane domain subunit NuoK (ND4L) of the NADH-quinone oxidoreductase from Escherichia coli.

Q6VY07	PACS1_HUMAN	Phosphofurin acidic cluster sorting protein 1	10707087	HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes.

P51687	SUOX_HUMAN	Sulfite oxidase, mitochondrial	9428520	Molecular basis of sulfite oxidase deficiency from the structure of sulfite oxidase.

P18537	FRIZ_DROME	Frizzled	10360843	Frizzled-suc2 fusion gene studies in Saccharomyces cerevisiae.

Q15399	TLR1_HUMAN	Toll-like receptor 1	11081518	Structural basis for signal transduction by the Toll/interleukin-1 receptor domains.

Q96S59	RANB9_HUMAN	Ran-binding protein 9	12220523	HIPK2 associates with RanBPM.

P16143	PO2F1_XENLA	POU domain, class 2, transcription factor 1	18241856	The POU homeobox protein Oct-1 regulates radial glia formation downstream of Notch signaling.

Q8BU27	PPM1M_MOUSE	Protein phosphatase 1M	14654243	Molecular cloning of PP2Ceta, a novel member of the protein phosphatase 2C family.

O60927	PP1RB_HUMAN	Protein phosphatase 1 regulatory subunit 11	9843442	Identification and characterization of the human HCG V gene product as a novel inhibitor of protein phosphatase-1.

P35453	HXD13_HUMAN	Homeobox protein Hox-D13	8614804	Altered growth and branching patterns in synpolydactyly caused by mutations in HOXD13.

P53170	YGF9_YEAST	Probable protein kinase YGL059W	14562095	Global analysis of protein localization in budding yeast.

O43463	SUV91_HUMAN	Histone-lysine N-methyltransferase SUV39H1	12711603	Methyl-CpG binding domain 1 (MBD1) interacts with the Suv39h1-HP1 heterochromatic complex for DNA methylation-based transcriptional repression.

Q08043	ACTN3_HUMAN	Alpha-actinin-3	1339456	Cloning and characterization of two human skeletal muscle alpha- actinin genes located on chromosomes 1 and 11.

O94906	PRP6_HUMAN	Pre-mRNA-processing factor 6	10788320	The human homologue of the yeast splicing factor Prp6p contains multiple TPR elements and is stably associated with the U5 snRNP via protein-protein interactions.

Q63621	IL1AP_RAT	Interleukin-1 receptor accessory protein	8964912	Rat homolog of mouse interleukin-1 receptor accessory protein: cloning, localization and modulation studies.

Q9C8J8	AB13G_ARATH	ABC transporter G family member 13	17951461	The Arabidopsis DESPERADO/AtWBC11 transporter is required for cutin and wax secretion.

Q6AWX6	SCAR1_ARATH	Protein SCAR1	15296761	Arabidopsis NAP1 is essential for Arp2/3-dependent trichome morphogenesis.

P83056	KNL1_BOMVA	Kininogen-1	15134346	Skin secretion of the toad Bombina variegata contains multiple insulin-releasing peptides including bombesin and entirely novel insulinotropic structures.

O94813	SLIT2_HUMAN	Slit homolog 2 protein	11309622	The neuronal repellent Slit inhibits leukocyte chemotaxis induced by chemotactic factors.

Q7TN50	MRGB8_RAT	Mas-related G-protein coupled receptor member B8	12909716	Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family.

P19785	ESR1_MOUSE	Estrogen receptor	8999954	A subpopulation of estrogen receptors are modified by O-linked N- acetylglucosamine.

Q61191	HCFC1_MOUSE	Host cell factor 1	9990006	Nuclear localization of the C1 factor (host cell factor) in sensory neurons correlates with reactivation of herpes simplex virus from latency.

P83297	GR64F_DROME	Putative gustatory receptor 64f	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

P08670	VIME_HUMAN	Vimentin	9150946	Two-dimensional electrophoretic analysis of human breast carcinoma proteins: mapping of proteins that bind to the SH3 domain of mixed lineage kinase MLK2.

P52955	LBX1_MOUSE	Transcription factor LBX1	15528197	Corl1, a novel neuronal lineage-specific transcriptional corepressor for the homeodomain transcription factor Lbx1.

Q9BT92	TCHP_HUMAN	Trichoplein keratin filament-binding protein	15731013	Identification of trichoplein, a novel keratin filament-binding protein.

P22105	TENX_HUMAN	Tenascin-X	7686164	Tenascin-X: a novel extracellular matrix protein encoded by the human XB gene overlapping P450c21B.

O08707	CCBP2_MOUSE	Chemokine-binding protein 2	9139699	Cloning and characterization of a novel murine beta chemokine receptor, D6. Comparison to three other related macrophage inflammatory protein-1alpha receptors, CCR-1, CCR-3, and CCR-5.

O95832	CLD1_HUMAN	Claudin-1	9931503	SEMP1, a senescence-associated cDNA isolated from human mammary epithelial cells, is a member of an epithelial membrane protein superfamily.

O75603	GCM2_HUMAN	Chorion-specific transcription factor GCMb	15863676	Identification of a novel mutation disrupting the DNA binding activity of GCM2 in autosomal recessive familial isolated hypoparathyroidism.

Q8GYB1	NUD15_ARATH	Nudix hydrolase 15, mitochondrial	18815383	Molecular characterization of organelle-type Nudix hydrolases in Arabidopsis.

Q793I8	TIFA_MOUSE	TRAF-interacting protein with FHA domain-containing protein A	11798190	T2BP, a novel TRAF2 binding protein, can activate NF-kappaB and AP-1 without TNF stimulation.

O82794	AGL24_ARATH	MADS-box protein AGL24	12609028	AGL24 acts as a promoter of flowering in Arabidopsis and is positively regulated by vernalization.

P40089	LSM5_YEAST	U6 snRNA-associated Sm-like protein LSm5	10369684	Sm and Sm-like proteins assemble in two related complexes of deep evolutionary origin.

Q6MG08	ABCF1_RAT	ATP-binding cassette sub-family F member 1	10931828	ABC50 interacts with eukaryotic initiation factor 2 and associates with the ribosome in an ATP-dependent manner.

Q64380	SARDH_RAT	Sarcosine dehydrogenase, mitochondrial	9839943	Molecular cloning and tissue distribution of rat sarcosine dehydrogenase.

Q9SB04	ARR5_ARATH	Two-component response regulator ARR5	11115887	Characterization of the response of the Arabidopsis response regulator gene family to cytokinin.

Q9JKE9	TA2R7_RAT	Taste receptor type 2 member 7	10761934	A novel family of mammalian taste receptors.

Q9C0C2	TB182_HUMAN	182 kDa tankyrase-1-binding protein	11854288	The telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a novel acceptor, 182-kDa tankyrase-binding protein (TAB182).

O42943	YBP8_SCHPO	Uncharacterized ABC transporter ATP-binding protein C16H5.08c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q04912	RON_HUMAN	Macrophage-stimulating protein receptor	15184888	Interplay between scatter factor receptors and B plexins controls invasive growth.

P29421	IAAS_ORYSJ	Alpha-amylase/subtilisin inhibitor	1511747	The amino acid sequence of a 20 kDa bifunctional subtilisin/alpha- amylase inhibitor from bran of rice (Oryza sativa L.) seeds.

Q9LKA3	MDHM2_ARATH	Malate dehydrogenase 2, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q9GZL7	WDR12_HUMAN	Ribosome biogenesis protein WDR12	16043514	Mammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferation.

Q86W33	TPRA1_HUMAN	Transmembrane protein adipocyte-associated 1	10342878	Differential expression of a novel seven transmembrane domain protein in epididymal fat from aged and diabetic mice.

Q07666	KHDR1_HUMAN	KH domain-containing, RNA-binding, signal transduction-associated protein 1	9045636	Interaction between Sam68 and Src family tyrosine kinases, Fyn and Lck, in T cell receptor signaling.

P49281	NRAM2_HUMAN	Natural resistance-associated macrophage protein 2	17109629	Functional properties of multiple isoforms of human divalent metal- ion transporter 1 (DMT1).

Q8R4E4	MYOZ3_MOUSE	Myozenin-3	11842093	Calsarcin-3, a novel skeletal muscle-specific member of the calsarcin family, interacts with multiple Z-disc proteins.

O00186	STXB3_HUMAN	Syntaxin-binding protein 3	10194441	Human platelets contain SNARE proteins and a Sec1p homologue that interacts with syntaxin 4 and is phosphorylated after thrombin activation: implications for platelet secretion.

Q9MA17	SMB_ARATH	Protein SOMBRERO	19081078	The NAC domain transcription factors FEZ and SOMBRERO control the orientation of cell division plane in Arabidopsis root stem cells.

Q06263	VTA1_YEAST	Vacuolar protein sorting-associated protein VTA1	16601096	Vta1p and Vps46p regulate the membrane association and ATPase activity of Vps4p at the yeast multivesicular body.

P01563	IFNA2_HUMAN	Interferon alpha-2	6158094	At least three human type alpha interferons: structure of alpha 2.

O94630	YGEC_SCHPO	Uncharacterized actin family protein C1347.12	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q03178	PIR1_YEAST	Cell wall mannoprotein PIR1	15781460	Comprehensive proteomic analysis of Saccharomyces cerevisiae cell walls: identification of proteins covalently attached via glycosylphosphatidylinositol remnants or mild alkali-sensitive linkages.

Q9JIA3	IKBB_RAT	NF-kappa-B inhibitor beta	10827092	Inhibitory and stimulatory effects of lactacystin on expression of nitric oxide synthase type 2 in brain glial cells: the role of I kappa B-beta.

Q86UN3	R4RL2_HUMAN	Reticulon-4 receptor-like 2	14664809	Two novel mammalian nogo receptor homologs differentially expressed in the central and peripheral nervous systems.

P23871	HEMH_ECOLI	Ferrochelatase	2051480	Isolation and characterization of visible light-sensitive mutants of Escherichia coli K12.

P12938	CP2D3_RAT	Cytochrome P450 2D3	9434752	Expression of four rat CYP2D isoforms in Saccharomyces cerevisiae and their catalytic specificity.

Q8W4Q5	RIN3_ARATH	E3 ubiquitin protein ligase RIN3	16212605	A duplicated pair of Arabidopsis RING-finger E3 ligases contribute to the RPM1- and RPS2-mediated hypersensitive response.

O60613	SEP15_HUMAN	15 kDa selenoprotein	9535873	A new human selenium-containing protein. Purification, characterization, and cDNA sequence.

P22353	RM08_YEAST	54S ribosomal protein L8, mitochondrial	2183197	Cloning and characterization of nuclear genes for two mitochondrial ribosomal proteins in Saccharomyces cerevisiae.

P38814	SBE22_YEAST	Protein SBE22	10679005	Sbe2p and sbe22p, two homologous Golgi proteins involved in yeast cell wall formation.

Q9NRJ4	TULP4_HUMAN	Tubby-related protein 4	11595174	Molecular cloning and characterization of the mouse and human TUSP gene, a novel member of the tubby superfamily.

P03372	ESR1_HUMAN	Estrogen receptor	10359819	An estrogen receptor-selective coregulator that potentiates the effectiveness of antiestrogens and represses the activity of estrogens.

Q9FZF1	PX11A_ARATH	Peroxisomal membrane protein 11A	17220199	The PEROXIN11 protein family controls peroxisome proliferation in Arabidopsis.

O48676	HTGT_ARATH	N-hydroxythioamide S-beta-glucosyltransferase	15584955	Arabidopsis glucosyltransferase UGT74B1 functions in glucosinolate biosynthesis and auxin homeostasis.

P22309	UD11_HUMAN	UDP-glucuronosyltransferase 1-1	1898728	Cloning of two human liver bilirubin UDP-glucuronosyltransferase cDNAs with expression in COS-1 cells.

O14212	YDT7_SCHPO	Uncharacterized RING finger protein C6B12.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q6PAL8	DEN5A_MOUSE	DENN domain-containing protein 5A	19141279	Structural basis for recruitment of Rab6-interacting protein 1 to Golgi via a RUN domain.

P40941	ADT2_ARATH	ADP,ATP carrier protein 2, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q9UPG8	PLAL2_HUMAN	Zinc finger protein PLAGL2	9722527	Transcriptional activation capacity of the novel PLAG family of zinc finger proteins.

Q9DD02	CK073_MOUSE	Uncharacterized protein C11orf73 homolog	16157679	L7Rn6 encodes a novel protein required for Clara cell function in mouse lung development.

Q9R1R2	TRIM3_MOUSE	Tripartite motif-containing protein 3	11331580	The tripartite motif family identifies cell compartments.

P35169	TOR1_YEAST	Serine/threonine-protein kinase TOR1	12408816	Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control.

P47178	DAN1_YEAST	Cell wall protein DAN1	10322008	Deletion of new covalently linked cell wall glycoproteins alters the electrophoretic mobility of phosphorylated wall components of Saccharomyces cerevisiae.

Q04917	1433F_HUMAN	14-3-3 protein eta	19172738	Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein.

O88271	CFDP1_MOUSE	Craniofacial development protein 1	12153613	CP27 affects viability, proliferation, attachment and gene expression in embryonic fibroblasts.

P70498	PLD2_RAT	Phospholipase D2	9111050	Cloning, expression, and characterization of a novel phospholipase D complementary DNA from rat brain.

O60344	ECE2_HUMAN	Endothelin-converting enzyme 2	11718899	Human endothelin converting enzyme-2 (ECE2): characterization of mRNA species and chromosomal localization.

Q13023	AKAP6_HUMAN	A-kinase anchor protein 6	7721854	Cloning and characterization of A-kinase anchor protein 100 (AKAP100). A protein that targets A-kinase to the sarcoplasmic reticulum.

P69776	LPP_ECOLI	Major outer membrane lipoprotein Lpp	9701827	TolB protein of Escherichia coli K-12 interacts with the outer membrane peptidoglycan-associated proteins Pal, Lpp and OmpA.

P17894	RECN_BACSU	DNA repair protein recN	15186413	Visualization of DNA double-strand break repair in live bacteria reveals dynamic recruitment of Bacillus subtilis RecF, RecO and RecN proteins to distinct sites on the nucleoids.

Q90477	MYOD1_DANRE	Myoblast determination protein 1 homolog	8565839	Developmental regulation of zebrafish MyoD in wild-type, no tail and spadetail embryos.

Q9Y2B0	CNPY2_HUMAN	Protein canopy homolog 2	10072769	Selection of cDNAs encoding putative type II membrane proteins on the cell surface from a human full-length cDNA bank.

P53779	MK10_HUMAN	Mitogen-activated protein kinase 10	7826642	p493F12 kinase: a novel MAP kinase expressed in a subset of neurons in the human nervous system.

P22188	MURE_ECOLI	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase	2269304	Over-production, purification and properties of the uridine- diphosphate-N-acetylmuramoyl-L-alanyl-D-glutamate: meso-2,6- diaminopimelate ligase from Escherichia coli.

P53335	PXR1_YEAST	Protein PXR1	12107183	The yeast homolog of human PinX1 is involved in rRNA and small nucleolar RNA maturation, not in telomere elongation inhibition.

Q9H223	EHD4_HUMAN	EH domain-containing protein 4	10673336	EHD2, EHD3, and EHD4 encode novel members of a highly conserved family of EH domain-containing proteins.

Q99NF8	RBP17_MOUSE	Ran-binding protein 17	11071879	Identification of a novel putative Ran-binding protein and its close homologue.

Q95ST2	WLS_DROME	Protein wntless	16678096	Secretion of Wnt ligands requires Evi, a conserved transmembrane protein.

Q9NYB9	ABI2_HUMAN	Abl interactor 2	11516653	The Abl interactor proteins localize to sites of actin polymerization at the tips of lamellipodia and filopodia.

P39960	BEM2_YEAST	GTPase-activating protein BEM2/IPL2	7962098	Interactions between the bud emergence proteins Bem1p and Bem2p and Rho-type GTPases in yeast.

Q9BXJ9	NAA15_HUMAN	N-alpha-acetyltransferase 15, NatA auxiliary subunit	15496142	Identification and characterization of the human ARD1-NATH protein acetyltransferase complex.

Q9UPN9	TRI33_HUMAN	E3 ubiquitin-protein ligase TRIM33	10022127	TIF1gamma, a novel member of the transcriptional intermediary factor 1 family.

Q9VD73	GLEC_DROME	Gliolectin	11714683	Gliolectin-mediated carbohydrate binding at the Drosophila midline ensures the fidelity of axon pathfinding.

O49552	DDB1B_ARATH	DNA damage-binding protein 1b	12225661	De-etiolated 1 and damaged DNA binding protein 1 interact to regulate Arabidopsis photomorphogenesis.

Q9QZR8	PDZD2_RAT	PDZ domain-containing protein 2	12671685	Proteolytic cleavage of PDZD2 generates a secreted peptide containing two PDZ domains.

Q9JLB4	CUBN_MOUSE	Cubilin	10766831	Megalin acts in concert with cubilin to mediate endocytosis of high density lipoproteins.

P05059	CMGA_BOVIN	Chromogranin-A	12795588	Primary sequence characterization of catestatin intermediates and peptides defines proteolytic cleavage sites utilized for converting chromogranin A into active catestatin secreted from neuroendocrine chromaffin cells.

Q9QWN8	SPTN2_RAT	Spectrin beta chain, brain 2	9704016	A novel brain-specific isoform of beta spectrin: isolation and its interaction with Munc13.

Q80TR4	SLIT1_MOUSE	Slit homolog 1 protein	12097499	Slit1 and slit2 proteins control the development of the lateral olfactory tract.

Q99MU3	DSRAD_MOUSE	Double-stranded RNA-specific adenosine deaminase	14613934	Stress-induced apoptosis associated with null mutation of ADAR1 RNA editing deaminase gene.

Q03677	MTND_YEAST	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase	15938715	Membrane-type 1 matrix metalloproteinase cytoplasmic tail binding protein-1 (MTCBP-1) acts as an eukaryotic aci-reductone dioxygenase (ARD) in the methionine salvage pathway.

Q8IS18	GEFE_DICDI	Ras guanine nucleotide exchange factor E	16086850	The Dictyostelium genome encodes numerous RasGEFs with multiple biological roles.

O75326	SEM7A_HUMAN	Semaphorin-7A	9721204	New eukaryotic semaphorins with close homology to semaphorins of DNA viruses.

Q8IDG7	YPF01_PLAF7	Uncharacterized protein PF13_0277	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

Q04410	GRH1_YEAST	GRASP65 homolog protein 1	10417390	Genetic selection of peptide inhibitors of biological pathways.

P53903	YNO9_YEAST	Uncharacterized protein YNL149C	14562095	Global analysis of protein localization in budding yeast.

Q08460	KCMA1_MOUSE	Calcium-activated potassium channel subunit alpha-1	12388098	Molecular identification of Ca2+-activated K+ channels in parotid acinar cells.

P53893	RIA1_YEAST	Ribosome assembly protein 1	11779510	The nucle(ol)ar Tif6p and Efl1p are required for a late cytoplasmic step of ribosome synthesis.

Q9VWL5	INX5_DROME	Innexin inx5	11960713	Gap junctions in Drosophila: developmental expression of the entire innexin gene family.

P39010	AKR1_YEAST	Palmitoyltransferase AKR1	8524293	Interactions between the ankyrin repeat-containing protein Akr1p and the pheromone response pathway in Saccharomyces cerevisiae.

Q9UTE5	E2AK2_SCHPO	Eukaryotic translation initiation factor 2-alpha kinase 2	12242291	Phosphorylation of eukaryotic initiation factor 2 by heme-regulated inhibitor kinase-related protein kinases in Schizosaccharomyces pombe is important for resistance to environmental stresses.

Q64350	EI2BE_RAT	Translation initiation factor eIF-2B subunit epsilon	8688467	Cloning and characterization of complementary and genomic DNAs encoding the epsilon-subunit of rat translation initiation factor- 2B.

O42900	PPK19_SCHPO	Serine/threonine-protein kinase ppk19	15821139	Systematic deletion analysis of fission yeast protein kinases.

P24100	CDKA1_ARATH	Cyclin-dependent kinase A-1	11449057	Functional analysis of cyclin-dependent kinase inhibitors of Arabidopsis.

Q7XJM2	CCD7_ARATH	Carotenoid cleavage dioxygenase 7, chloroplastic	15268852	MAX3/CCD7 is a carotenoid cleavage dioxygenase required for the synthesis of a novel plant signaling molecule.

Q13426	XRCC4_HUMAN	DNA repair protein XRCC4	9259561	Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV.

Q76L34	PCYAA_ASTLO	Photoactivated adenylate cyclase subunit alpha	16121285	Photoactivated adenylyl cyclase (PAC) genes in the flagellate Euglena gracilis mutant strains.

P77165	YAGT_ECOLI	Putative xanthine dehydrogenase yagT iron-sulfur-binding subunit	17218314	Export pathway selectivity of Escherichia coli twin arginine translocation signal peptides.

P41888	TNR3_SCHPO	Thiamine pyrophosphokinase	1551569	Isolation and characterization of regulatory mutants from Schizosaccharomyces pombe involved in thiamine-regulated gene expression.

P19492	GRIA3_RAT	Glutamate receptor 3	10027300	Clustering of AMPA receptors by the synaptic PDZ domain-containing protein PICK1.

Q9UMD9	COHA1_HUMAN	Collagen alpha-1(XVII) chain	9012408	Cloning of the human type XVII collagen gene (COL17A1), and detection of novel mutations in generalized atrophic benign epidermolysis bullosa.

P25380	SPS22_YEAST	Sporulation-specific protein 22	15590821	Morphogenetic pathway of spore wall assembly in Saccharomyces cerevisiae.

Q6Q547	NOP10_YEAST	H/ACA ribonucleoprotein complex subunit 3	9843512	Nhp2p and Nop10p are essential for the function of H/ACA snoRNPs.

O14994	SYN3_HUMAN	Synapsin-3	9539796	A third member of the synapsin gene family.

P38203	LSM2_YEAST	U6 snRNA-associated Sm-like protein LSm2	10449419	Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6.U5] tri-snRNP.

P02994	EF1A_YEAST	Elongation factor 1-alpha	10514524	Mutations in a GTP-binding motif of eukaryotic elongation factor 1A reduce both translational fidelity and the requirement for nucleotide exchange.

Q10570	CPSF1_HUMAN	Cleavage and polyadenylation specificity factor subunit 1	7590244	The 160-kD subunit of human cleavage-polyadenylation specificity factor coordinates pre-mRNA 3'-end formation.

P52891	NUP84_YEAST	Nucleoporin NUP84	11823431	Modular self-assembly of a Y-shaped multiprotein complex from seven nucleoporins.

Q9FI39	THAD_ARATH	Cytochrome P450 705A5	18356490	Metabolic diversification -- independent assembly of operon-like gene clusters in different plants.

Q9U969	SWS_DROME	Neuropathy target esterase sws	15772346	Loss of swiss cheese/neuropathy target esterase activity causes disruption of phosphatidylcholine homeostasis and neuronal and glial death in adult Drosophila.

Q09892	HOG1_SCHPO	Mitogen-activated protein kinase sty1	16087744	Distinct signaling pathways respond to arsenite and reactive oxygen species in Schizosaccharomyces pombe.

P35183	AST1_YEAST	Protein AST1	7822420	Targeting of the yeast plasma membrane [H+]ATPase: a novel gene AST1 prevents mislocalization of mutant ATPase to the vacuole.

P62994	GRB2_RAT	Growth factor receptor-bound protein 2	7775428	Splicing isoforms of rat Ash/Grb2. Isolation and characterization of the cDNA and genomic DNA clones and implications for the physiological roles of the isoforms.

P0AB74	KBAY_ECOLI	D-tagatose-1,6-bisphosphate aldolase subunit kbaY	11976750	Two class II D-tagatose-bisphosphate aldolases from enteric bacteria.

P40084	RTR1_YEAST	RNA polymerase II subunit B1 CTD phosphatase RTR1	18408053	Rtr1 is the Saccharomyces cerevisiae homolog of a novel family of RNA polymerase II-binding proteins.

O43008	CRS1_SCHPO	Meiosis-specific cyclin crs1	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

Q16610	ECM1_HUMAN	Extracellular matrix protein 1	11165938	Recombinant human extracellular matrix protein 1 inhibits alkaline phosphatase activity and mineralization of mouse embryonic metatarsals in vitro.

P26309	CDC20_YEAST	APC/C activator protein CDC20	9501986	Cdc20 is essential for the cyclosome-mediated proteolysis of both Pds1 and Clb2 during M phase in budding yeast.

Q15697	ZN174_HUMAN	Zinc finger protein 174	7673192	Isolation and characterization of a novel zinc-finger protein with transcription repressor activity.

Q9S7P9	SNP33_ARATH	SNAP25 homologous protein SNAP33	12746539	The expression of the t-SNARE AtSNAP33 is induced by pathogens and mechanical stimulation.

P84215	TY13_BOMVA	Tryptophyllin-13	15134346	Skin secretion of the toad Bombina variegata contains multiple insulin-releasing peptides including bombesin and entirely novel insulinotropic structures.

Q9LW07	PGLR3_ARATH	Probable polygalacturonase At3g15720	14517339	Proteomic analysis of glycosylphosphatidylinositol-anchored membrane proteins.

Q5JRA6	MIA3_HUMAN	Melanoma inhibitory activity protein 3	17044017	TANGO is a tumor suppressor of malignant melanoma.

Q12457	YD026_YEAST	Myb domain-containing protein YDR026C	14562095	Global analysis of protein localization in budding yeast.

O14122	CUL4_SCHPO	Cullin-4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NTG7	SIRT3_HUMAN	NAD-dependent deacetylase sirtuin-3, mitochondrial	16788062	Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2.

Q9UGI0	ZRAN1_HUMAN	Ubiquitin thioesterase ZRANB1	11463333	Isolation and characterization of two novel A20-like proteins.

Q99259	DCE1_HUMAN	Glutamate decarboxylase 1	10671565	Alternative splicing of GAD67 results in the synthesis of a third form of glutamic-acid decarboxylase in human islets and other non- neural tissues.

Q15928	ZN141_HUMAN	Zinc finger protein 141	8268908	A zinc-finger gene ZNF141 mapping at 4p16.3/D4S90 is a candidate gene for the Wolf-Hirschhorn (4p-) syndrome.

P51149	RAB7A_HUMAN	Ras-related protein Rab-7a	16925951	Novel RING E3 ubiquitin ligases in breast cancer.

O15522	NKX28_HUMAN	Homeobox protein Nkx-2.8	9446603	A novel nk-2-related transcription factor associated with human fetal liver and hepatocellular carcinoma.

Q7Z460	CLAP1_HUMAN	CLIP-associating protein 1	16914514	Mammalian CLASP1 and CLASP2 cooperate to ensure mitotic fidelity by regulating spindle and kinetochore function.

O23404	PPDK1_ARATH	Pyruvate, phosphate dikinase 1, chloroplastic	16915520	The Arabidopsis PPDK gene is transcribed from two promoters to produce differentially expressed transcripts responsible for cytosolic and plastidic proteins.

P43884	PLIN1_RAT	Perilipin-1	9755872	Dephosphorylation of perilipin by protein phosphatases present in rat adipocytes.

Q9SAK2	KSB_ARATH	Ent-kaur-16-ene synthase, chloroplastic	9536043	The GA2 locus of Arabidopsis thaliana encodes ent-kaurene synthase of gibberellin biosynthesis.

P81160	DEJP_DROME	Ductus ejaculatorius peptide 99B	11846801	Ductus ejaculatorius peptide 99B (DUP99B), a novel Drosophila melanogaster sex-peptide pheromone.

Q13467	FZD5_HUMAN	Frizzled-5	8626800	A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled.

P39827	CDC10_CANAL	Cell division control protein 10	8152419	Homologs of the yeast neck filament associated genes: isolation and sequence analysis of Candida albicans CDC3 and CDC10.

P26309	CDC20_YEAST	APC/C activator protein CDC20	10704439	MAD3 encodes a novel component of the spindle checkpoint which interacts with Bub3p, Cdc20p, and Mad2p.

P40496	RT25_YEAST	37S ribosomal protein S25, mitochondrial	11278769	Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues.

Q8IV08	PLD3_HUMAN	Phospholipase D3	9140189	A human homolog of the vaccinia virus HindIII K4L gene is a member of the phospholipase D superfamily.

O35526	STX1A_MOUSE	Syntaxin-1A	17055430	Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse.

O94508	CWF11_SCHPO	Cell cycle control protein cwf11	11884590	Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

Q12276	YO227_YEAST	Uncharacterized protein YOR227W	14562095	Global analysis of protein localization in budding yeast.

Q9ZVH4	CUL3A_ARATH	Cullin-3A	16045478	Arabidopsis CUL3A and CUL3B genes are essential for normal embryogenesis.

Q920G2	NHRF2_RAT	Na(+)/H(+) exchange regulatory cofactor NHE-RF2	11457882	Loss of glomerular foot processes is associated with uncoupling of podocalyxin from the actin cytoskeleton.

Q7M3M8	CAS_DROME	Transcription factor castor	9436984	Regulation of POU genes by castor and hunchback establishes layered compartments in the Drosophila CNS.

Q9UHV7	MED13_HUMAN	Mediator of RNA polymerase II transcription subunit 13	10235266	Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex.

O88561	S27A3_MOUSE	Long-chain fatty acid transport protein 3	15469937	Mouse very long-chain acyl-CoA synthetase 3/fatty acid transport protein 3 catalyzes fatty acid activation but not fatty acid transport in MA-10 cells.

Q8RYD9	TT16_ARATH	Protein TRANSPARENT TESTA 16	12368498	The TRANSPARENT TESTA16 locus encodes the ARABIDOPSIS BSISTER MADS domain protein and is required for proper development and pigmentation of the seed coat.

Q9V5M6	LOLA5_DROME	Longitudinals lacking protein, isoforms J/P/Q/S/Z	8050351	Lola encodes a putative transcription factor required for axon growth and guidance in Drosophila.

Q75K28	NCSA_DICDI	Calcium-binding protein NCSA	15606490	Disruption of the NCS-1/frequenin-related ncsA gene in Dictyostelium discoideum accelerates development.

P31007	DLG1_DROME	Disks large 1 tumor suppressor protein	12657668	Novel isoforms of Dlg are fundamental for neuronal development in Drosophila.

P29496	MCM5_YEAST	Minichromosome maintenance protein 5	15023545	Saccharomyces cerevisiae CSM1 gene encoding a protein influencing chromosome segregation in meiosis I interacts with elements of the DNA replication complex.

P36193	DROS_DROME	Drosocin	8325867	A novel inducible antibacterial peptide of Drosophila carries an O- glycosylated substitution.

Q94490	UBCB_DICDI	Ubiquitin conjugating enzyme E2 B	9348538	A ubiquitin-conjugating enzyme is essential for developmental transitions in Dictyostelium.

O14986	PI51B_HUMAN	Phosphatidylinositol-4-phosphate 5-kinase type-1 beta	8955136	Type I phosphatidylinositol-4-phosphate 5-kinases are distinct members of this novel lipid kinase family.

Q96288	STO_ARATH	Salt tolerance protein	11226162	Identification of a structural motif that confers specific interaction with the WD40 repeat domain of Arabidopsis COP1.

Q9UBV7	B4GT7_HUMAN	Beta-1,4-galactosyltransferase 7	10438455	Human homolog of Caenorhabditis elegans sqv-3 gene is galactosyltransferase I involved in the biosynthesis of the glycosaminoglycan-protein linkage region of proteoglycans.

Q38890	GUN25_ARATH	Endoglucanase 25	10899980	KORRIGAN, an Arabidopsis endo-1,4-beta-glucanase, localizes to the cell plate by polarized targeting and is essential for cytokinesis.

P47872	SCTR_HUMAN	Secretin receptor	7612008	Molecular cloning and functional characterization of a human secretin receptor.

P54360	FOJO_DROME	Protein four-jointed	8606003	Positional information along the dorsal-ventral axis of the Drosophila eye: graded expression of the four-jointed gene.

Q9JJG0	TACC2_MOUSE	Transforming acidic coiled-coil-containing protein 2	17920017	Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool.

Q14831	GRM7_HUMAN	Metabotropic glutamate receptor 7	9144652	A novel splice variant of a metabotropic glutamate receptor, human mGluR7b.

Q54N80	FKBP3_DICDI	FK506-binding protein 3	16087752	Transcriptional switch of the dia1 and impA promoter during the growth/differentiation transition.

P23497	SP100_HUMAN	Nuclear autoantigen Sp-100	8810287	The interferon (IFN)-stimulated gene Sp100 promoter contains an IFN- gamma activation site and an imperfect IFN-stimulated response element which mediate type I IFN inducibility.

P37610	TAUD_ECOLI	Alpha-ketoglutarate-dependent taurine dioxygenase	9287300	Characterization of alpha-ketoglutarate-dependent taurine dioxygenase from Escherichia coli.

Q15223	PVRL1_HUMAN	Poliovirus receptor-related protein 1	10225955	Nectin/PRR: an immunoglobulin-like cell adhesion molecule recruited to cadherin-based adherens junctions through interaction with Afadin, a PDZ domain-containing protein.

Q00987	MDM2_HUMAN	E3 ubiquitin-protein ligase Mdm2	10707090	Identification of a cryptic nucleolar-localization signal in MDM2.

P15104	GLNA_HUMAN	Glutamine synthetase	2888076	Sequence of a human glutamine synthetase cDNA.

P53201	SWC4_YEAST	SWR1-complex protein 4	15353583	Regulation of chromosome stability by the histone H2A variant Htz1, the Swr1 chromatin remodeling complex, and the histone acetyltransferase NuA4.

O74945	RIA1_SCHPO	Ribosome assembly protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9FH16	PR1G2_ARATH	PRA1 family protein G2	18583532	The PRA1 gene family in Arabidopsis.

Q9R0Q1	SYTL4_MOUSE	Synaptotagmin-like protein 4	12590134	Slp4-a/granuphilin-a inhibits dense-core vesicle exocytosis through interaction with the GDP-bound form of Rab27A in PC12 cells.

Q9HB96	FANCE_HUMAN	Fanconi anemia group E protein	11001585	Isolation of a cDNA representing the Fanconi anemia complementation group E gene.

P54003	SUR7_YEAST	Protein SUR7	16496001	Eisosomes mark static sites of endocytosis.

Q99380	OST4_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST4	15831493	Subunits of the translocon interact with components of the oligosaccharyl transferase complex.

P39712	FLO9_YEAST	Flocculation protein FLO9	7502576	Review: the dominant flocculation genes of Saccharomyces cerevisiae constitute a new subtelomeric gene family.

Q12518	ENT1_YEAST	Epsin-1	10449404	Yeast epsins contain an essential N-terminal ENTH domain, bind clathrin and are required for endocytosis.

O74783	POF2_SCHPO	SCF E3 ubiquitin ligase complex F-box protein pof2	15147268	Molecular interactions of fission yeast Skp1 and its role in the DNA damage checkpoint.

Q30201	HFE_HUMAN	Hereditary hemochromatosis protein	10638746	Crystal structure of the hereditary haemochromatosis protein HFE complexed with transferrin receptor.

Q9Y262	EIF3L_HUMAN	Eukaryotic translation initiation factor 3 subunit L	18599441	Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3.

Q04226	TAF11_YEAST	Transcription initiation factor TFIID subunit 11	12138208	Molecular characterization of Saccharomyces cerevisiae TFIID.

Q86UK0	ABCAC_HUMAN	ATP-binding cassette sub-family A member 12	12915478	Mutations in the transporter ABCA12 are associated with lamellar ichthyosis type 2.

Q02516	HAP5_YEAST	Transcriptional activator HAP5	7828851	Cloning of yeast HAP5: a novel subunit of a heterotrimeric complex required for CCAAT binding.

P0ABZ6	SURA_ECOLI	Chaperone surA	14506253	The periplasmic molecular chaperone protein SurA binds a peptide motif that is characteristic of integral outer membrane proteins.

P28222	5HT1B_HUMAN	5-hydroxytryptamine receptor 1B	1351684	A human serotonin 1D receptor variant (5HT1D beta) encoded by an intronless gene on chromosome 6.

Q6VVW5	ANPRB_MOUSE	Atrial natriuretic peptide receptor 2	14514678	Regulation of the guanylyl cyclase-B receptor by alternative splicing.

P29372	3MG_HUMAN	DNA-3-methyladenine glycosylase	1645538	Human cDNA expressing a functional DNA glycosylase excising 3- methyladenine and 7-methylguanine.

Q9C7G1	PUB45_ARATH	U-box domain-containing protein 45	14657406	A large complement of the predicted Arabidopsis ARM repeat proteins are members of the U-box E3 ubiquitin ligase family.

Q9Y6Q9	NCOA3_HUMAN	Nuclear receptor coactivator 3	9238002	RAC3, a steroid/nuclear receptor-associated coactivator that is related to SRC-1 and TIF2.

P50944	AVT4_YEAST	Vacuolar amino acid transporter 4	11274162	A family of yeast proteins mediating bidirectional vacuolar amino acid transport.

P59438	HPS5_MOUSE	Hermansky-Pudlak syndrome 5 protein homolog	12548288	Ru2 and Ru encode mouse orthologs of the genes mutated in human Hermansky-Pudlak syndrome types 5 and 6.

Q9XUJ7	DKF1_CAEEL	Serine/threonine-protein kinase dkf-1	16613842	Conserved domains subserve novel mechanisms and functions in DKF-1, a Caenorhabditis elegans protein kinase D.

O82660	P2SAF_ARATH	Photosystem II stability/assembly factor HCF136, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

P25618	CWH43_YEAST	Protein CWH43	11427965	Saccharomyces cerevisiae YCRO17c/CWH43 encodes a putative sensor/transporter protein upstream of the BCK2 branch of the PKC1- dependent cell wall integrity pathway.

P39315	QOR2_ECOLI	Quinone oxidoreductase 2	18455185	Crystal structure of a new type of NADPH-dependent quinone oxidoreductase (QOR2) from Escherichia coli.

O14647	CHD2_HUMAN	Chromodomain-helicase-DNA-binding protein 2	9326634	Characterization of the CHD family of proteins.

Q9QUS4	HEY2_MOUSE	Hairy/enhancer-of-split related with YRPW motif protein 2	17332425	CHF1/Hey2 plays a pivotal role in left ventricular maturation through suppression of ectopic atrial gene expression.

Q15562	TEAD2_HUMAN	Transcriptional enhancer factor TEF-4	18579750	TEAD mediates YAP-dependent gene induction and growth control.

P35568	IRS1_HUMAN	Insulin receptor substrate 1	12679424	A novel T608R missense mutation in insulin receptor substrate-1 identified in a subject with type 2 diabetes impairs metabolic insulin signaling.

P30429	CED4_CAEEL	Cell death protein 4	1286611	The Caenorhabditis elegans cell death gene ced-4 encodes a novel protein and is expressed during the period of extensive programmed cell death.

P06733	ENOA_HUMAN	Alpha-enolase	16548883	Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection.

Q54QT7	CBPC_DICDI	Calcium-binding protein C	15843041	Dictyostelium CBP3 associates with actin cytoskeleton and is related to slug migration.

Q9P7U7	YP13_SCHPO	Uncharacterized protein P4G3.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NW64	RBM22_HUMAN	Pre-mRNA-splicing factor RBM22	17045351	Nuclear translocation of the calcium-binding protein ALG-2 induced by the RNA-binding protein RBM22.

Q9Y265	RUVB1_HUMAN	RuvB-like 1	9588198	TIP49, homologous to the bacterial DNA helicase RuvB, acts as an autoantigen in human.

P36520	RM10_YEAST	54S ribosomal protein L10, mitochondrial	9151978	Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae.

Q12497	FMP16_YEAST	Protein FMP16, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q9D1M4	MCA3_MOUSE	Eukaryotic translation elongation factor 1 epsilon-1	15680327	The haploinsufficient tumor suppressor p18 upregulates p53 via interactions with ATM/ATR.

Q96J02	ITCH_HUMAN	E3 ubiquitin-protein ligase Itchy homolog	20491914	The E3 ubiquitin ligase Itch regulates sorting nexin 9 through an unconventional substrate recognition domain.

Q9BZZ5	API5_HUMAN	Apoptosis inhibitor 5	9307294	AAC-11, a novel cDNA that inhibits apoptosis after growth factor withdrawal.

P32722	PORD_PSEAE	Porin D	2118530	Protein D2 channel of the Pseudomonas aeruginosa outer membrane has a binding site for basic amino acids and peptides.

Q61152	PTN18_MOUSE	Tyrosine-protein phosphatase non-receptor type 18	9265651	PSTPIP: a tyrosine phosphorylated cleavage furrow-associated protein that is a substrate for a PEST tyrosine phosphatase.

Q8VYC8	RIN2_ARATH	E3 ubiquitin protein ligase RIN2	16212605	A duplicated pair of Arabidopsis RING-finger E3 ligases contribute to the RPM1- and RPS2-mediated hypersensitive response.

Q14833	GRM4_HUMAN	Metabotropic glutamate receptor 4	8738157	Molecular characterization and localization of human metabotropic glutamate receptor type 4.

P84867	RNAM_PLEOS	Ribonuclease	15946190	A low-molecular mass ribonuclease from the brown oyster mushroom.

Q9UKV5	AMFR2_HUMAN	E3 ubiquitin-protein ligase AMFR	11724934	The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum.

Q54X65	BRK1_DICDI	Protein BRICK1	17314411	The N-terminus of Dictyostelium Scar interacts with Abi and HSPC300 and is essential for proper regulation and function.

Q8BG22	CLCA2_MOUSE	Calcium-activated chloride channel regulator 2	15284223	Molecular and functional analyses of two new calcium-activated chloride channel family members from mouse eye and intestine.

Q86Y01	DTX1_HUMAN	Protein deltex-1	9590294	Human deltex is a conserved regulator of Notch signalling.

Q9FHW7	SKP1B_ARATH	SKP1-like protein 1B	16446454	F-box-like domain in the polerovirus protein P0 is required for silencing suppressor function.

P51617	IRAK1_HUMAN	Interleukin-1 receptor-associated kinase 1	11397809	IRAK1b, a novel alternative splice variant of interleukin-1 receptor- associated kinase (IRAK), mediates interleukin-1 signaling and has prolonged stability.

Q14498	RBM39_HUMAN	RNA-binding protein 39	8227358	Novel nuclear autoantigen with splicing factor motifs identified with antibody from hepatocellular carcinoma.

Q9Z319	CORIN_MOUSE	Atrial natriuretic peptide-converting enzyme	15637153	Hypertension in mice lacking the proatrial natriuretic peptide convertase corin.

Q13303	KCAB2_HUMAN	Voltage-gated potassium channel subunit beta-2	7649300	Alternative splicing of the human Shaker K+ channel beta 1 gene and functional expression of the beta 2 gene product.

P32895	KPR1_YEAST	Ribose-phosphate pyrophosphokinase 1	15280369	Heterooligomeric phosphoribosyl diphosphate synthase of Saccharomyces cerevisiae: combinatorial expression of the five PRS genes in Escherichia coli.

Q9W0K0	JIP1_DROME	JNK-interacting protein 1	11912189	Interaction of Alzheimer's beta-amyloid precursor family proteins with scaffold proteins of the JNK signaling cascade.

Q03388	VPS72_YEAST	Vacuolar protein sorting-associated protein 72	14645854	ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex.

Q9NL82	ORCKB_PROCL	Orcokinin peptides type B	10753578	Identification of orcokinin gene-related peptides in the brain of the crayfish Procambarus clarkii by the combination of MALDI-TOF and on- line capillary HPLC/Q-Tof mass spectrometries and molecular cloning.

Q3KRE8	TBB2B_RAT	Tubulin beta-2B chain	19465910	Mutations in the beta-tubulin gene TUBB2B result in asymmetrical polymicrogyria.

Q99NE9	PBX4_MOUSE	Pre-B-cell leukemia transcription factor 4	11335119	Pbx4, a new Pbx family member on mouse chromosome 8 is expressed during spermatogenesis.

P86316	BDEF_VENPH	Big defensin	14673509	Purification of a big defensin from Ruditapes philippinesis and its antibacterial activity.

P78562	PHEX_HUMAN	Phosphate-regulating neutral endopeptidase	7550339	A gene (PEX) with homologies to endopeptidases is mutated in patients with X-linked hypophosphatemic rickets.

P70429	EVL_MOUSE	Ena/VASP-like protein	14506234	Tuba, a novel protein containing bin/amphiphysin/Rvs and Dbl homology domains, links dynamin to regulation of the actin cytoskeleton.

Q8VYF5	AGUB_ARATH	N-carbamoylputrescine amidase	12435743	Plant C-N hydrolases and the identification of a plant N- carbamoylputrescine amidohydrolase involved in polyamine biosynthesis.

O43497	CAC1G_HUMAN	Voltage-dependent T-type calcium channel subunit alpha-1G	9495342	Molecular characterization of a neuronal low-voltage-activated T-type calcium channel.

P25874	UCP1_HUMAN	Mitochondrial brown fat uncoupling protein 1	2380264	Human uncoupling protein gene: structure, comparison with rat gene, and assignment to the long arm of chromosome 4.

Q8WXG1	RSAD2_HUMAN	Radical S-adenosyl methionine domain-containing protein 2	11752458	Viperin (cig5), an IFN-inducible antiviral protein directly induced by human cytomegalovirus.

P27900	GL1_ARATH	Trichome differentiation protein GL1	11063707	GL3 encodes a bHLH protein that regulates trichome development in arabidopsis through interaction with GL1 and TTG1.

P25705	ATPA_HUMAN	ATP synthase subunit alpha, mitochondrial	1830491	Nucleotide sequence of a cDNA for the alpha subunit of human mitochondrial ATP synthase.

Q9VYS4	GLD2B_DROME	Poly(A) RNA polymerase gld-2 homolog B	18430932	Wispy, the Drosophila homolog of GLD-2, is required during oogenesis and egg activation.

Q8GYH7	NSE2_ARATH	E3 SUMO-protein ligase MMS21	19682286	The Arabidopsis SUMO E3 ligase AtMMS21, a homologue of NSE2/MMS21, regulates cell proliferation in the root.

P38398	BRCA1_HUMAN	Breast cancer type 1 susceptibility protein	16326698	BRCA1 affects lipid synthesis through its interaction with acetyl-CoA carboxylase.

P56819	BACE1_RAT	Beta-secretase 1	10531052	Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE.

Q5EAK6	ATM_DROME	Serine/threonine-protein kinase ATM	15296751	Telomere protection without a telomerase; the role of ATM and Mre11 in Drosophila telomere maintenance.

P01603	KV111_HUMAN	Ig kappa chain V-I region Ka	818073	Comparative structural studies on the light chains of human immunoglobulins. I. Protein Ka with the Inv(3) allotypic marker.

P87245	KMS1_SCHPO	Karyogamy meiotic segregation protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8N9R8	SCAI_HUMAN	Protein SCAI	19350017	SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta1-integrin.

P67087	RSMI_ECOLI	Ribosomal RNA small subunit methyltransferase I	19965768	Fine-tuning of the ribosomal decoding center by conserved methyl- modifications in the Escherichia coli 16S rRNA.

P40305	IFI27_HUMAN	Interferon alpha-inducible protein 27, mitochondrial	18330707	Mitochondrial localization and pro-apoptotic effects of the interferon-inducible protein ISG12a.

O88279	SLIT1_RAT	Slit homolog 1 protein	10102268	Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance.

P36156	GTO2_YEAST	Glutathione S-transferase omega-like 2	9335584	Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae.

P70259	GP143_MOUSE	G-protein coupled receptor 143	18697795	The ocular albinism type 1 protein, an intracellular G protein- coupled receptor, regulates melanosome transport in pigment cells.

P60334	CDO1_MOUSE	Cysteine dioxygenase type 1	11602353	Murine cysteine dioxygenase gene: structural organization, tissue- specific expression and promoter identification.

Q9H0E7	UBP44_HUMAN	Ubiquitin carboxyl-terminal hydrolase 44	17443180	Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities.

Q24437	MST40_DROME	Protein male-specific 40	8013257	A Drosophila melanogaster chromosome-2L repeat is expressed in the male germ line.

Q96S44	PRPK_HUMAN	TP53-regulating kinase	11546806	Cloning and characterization of a p53-related protein kinase expressed in interleukin-2-activated cytotoxic T-cells, epithelial tumor cell lines, and the testes.

O95237	LRAT_HUMAN	Lecithin retinol acyltransferase	9920938	Molecular and biochemical characterization of lecithin retinol acyltransferase.

P69432	PGAD_ECOLI	Biofilm PGA synthesis protein PgaD	15090514	The pgaABCD locus of Escherichia coli promotes the synthesis of a polysaccharide adhesin required for biofilm formation.

P20449	DBP5_YEAST	ATP-dependent RNA helicase DBP5	9564048	Dbp5p/Rat8p is a yeast nuclear pore-associated DEAD-box protein essential for RNA export.

Q01196	RUNX1_HUMAN	Runt-related transcription factor 1	11742995	Activation of AML1-mediated transcription by MOZ and inhibition by the MOZ-CBP fusion protein.

P40071	TMN3_YEAST	Transmembrane 9 superfamily member 3	18178563	Control of cellular physiology by TM9 proteins in yeast and Dictyostelium.

P53724	RM50_YEAST	54S ribosomal protein L50, mitochondrial	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

P03407	NEF_HV1A2	Protein Nef	9620685	Interactions between HIV1 Nef and vacuolar ATPase facilitate the internalization of CD4.

Q9ZWS9	ARR3_ARATH	Two-component response regulator ARR3	9482949	Response regulators implicated in His-to-Asp phosphotransfer signaling in Arabidopsis.

P16615	AT2A2_HUMAN	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	2844796	Molecular cloning of cDNAs from human kidney coding for two alternatively spliced products of the cardiac Ca2+-ATPase gene.

P49753	ACOT2_HUMAN	Acyl-coenzyme A thioesterase 2, mitochondrial	16940157	Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs.

P51946	CCNH_HUMAN	Cyclin-H	9852112	Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.

Q9EQY6	PIGM_RAT	GPI mannosyltransferase 1	11226175	PIG-M transfers the first mannose to glycosylphosphatidylinositol on the lumenal side of the ER.

Q12016	VPS68_YEAST	Vacuolar protein sorting-associated protein 68	14562095	Global analysis of protein localization in budding yeast.

P41743	KPCI_HUMAN	Protein kinase C iota type	12893243	Centaurin-alpha(1) associates with and is phosphorylated by isoforms of protein kinase C.

O60256	KPRB_HUMAN	Phosphoribosyl pyrophosphate synthase-associated protein 2	9545573	Molecular cloning of a human cDNA for the 41-kDa phosphoribosylpyrophosphate synthetase-associated protein.

P70056	FOXH1_XENLA	Forkhead box protein H1	9288972	Smad4 and FAST-1 in the assembly of activin-responsive factor.

Q7DMA9	PAS1_ARATH	Peptidyl-prolyl isomerase PASTICCINO1	9449673	The PASTICCINO genes of Arabidopsis thaliana are involved in the control of cell division and differentiation.

P31225	CBP1_CANAL	Corticosteroid-binding protein	8446606	Cloning and expression of the gene from Candida albicans that encodes a high-affinity corticosteroid-binding protein.

Q9Z0H8	CLIP2_MOUSE	CAP-Gly domain-containing linker protein 2	11290329	Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts.

Q6ZMT4	KDM7_HUMAN	Lysine-specific demethylase 7	20194436	KDM7 is a dual demethylase for histone H3 Lys 9 and Lys 27 and functions in brain development.

Q9ERZ6	FIGN_MOUSE	Fidgetin	16751186	Interaction between fidgetin and protein kinase A-anchoring protein AKAP95 is critical for palatogenesis in the mouse.

O13650	SFC9_SCHPO	Putative transcription factor tau subunit sfc9	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P01705	LV202_HUMAN	Ig lambda chain V-II region NEI	5043326	The primary structure of a monoclonal human lambda-type immunoglobulin L-chain of subgroup II (Bence-Jones protein NEI).

P30203	CD6_HUMAN	T-cell differentiation antigen CD6	1919444	The lymphocyte glycoprotein CD6 contains a repeated domain structure characteristic of a new family of cell surface and secreted proteins.

P32851	STX1A_RAT	Syntaxin-1A	11709063	Regulation of the serotonin transporter by interacting proteins.

Q9W1R5	VIR_DROME	Protein virilizer	11156988	Molecular identification of virilizer, a gene required for the expression of the sex-determining gene Sex-lethal in Drosophila melanogaster.

O54838	DUS5_RAT	Dual specificity protein phosphatase 5	9699150	Hippocampal plasticity involves extensive gene induction and multiple cellular mechanisms.

P40385	REC6_SCHPO	Meiotic recombination protein rec6	8005432	Transient, meiosis-induced expression of the rec6 and rec12 genes of Schizosaccharomyces pombe.

O95835	LATS1_HUMAN	Serine/threonine-protein kinase LATS1	19739119	Molecular characterization of human homologs of yeast MOB1.

Q96T83	SL9A7_HUMAN	Sodium/hydrogen exchanger 7	15840657	Secretory carrier membrane proteins interact and regulate trafficking of the organellar (Na+,K+)/H+ exchanger NHE7.

Q9LK35	THE1_ARATH	Receptor-like protein kinase THESEUS 1	19383785	Three related receptor-like kinases are required for optimal cell elongation in Arabidopsis thaliana.

Q15643	TRIPB_HUMAN	Thyroid receptor-interacting protein 11	9256431	A thyroid hormone receptor coactivator negatively regulated by the retinoblastoma protein.

Q9LJL4	IPT8_ARATH	Adenylate isopentenyltransferase 8, chloroplastic	17062755	Roles of Arabidopsis ATP/ADP isopentenyltransferases and tRNA isopentenyltransferases in cytokinin biosynthesis.

Q22472	RIC3_CAEEL	Resistance to inhibitors of cholinesterase protein 3	16466809	Visualization of integral and peripheral cell surface proteins in live Caenorhabditis elegans.

P32722	PORD_PSEAE	Porin D	8012497	Two-dimensional polyacrylamide gel electrophoresis isolation and microsequencing of Pseudomonas aeruginosa proteins.

O94649	ATG2_SCHPO	Autophagy-related protein 2	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

P32768	FLO1_YEAST	Flocculation protein FLO1	9851992	Region of FLO1 proteins responsible for sugar recognition.

O81852	AKH2_ARATH	Bifunctional aspartokinase/homoserine dehydrogenase 2, chloroplastic	16216875	Identification of six novel allosteric effectors of Arabidopsis thaliana aspartate kinase-homoserine dehydrogenase isoforms. Physiological context sets the specificity.

O59700	YN43_SCHPO	Uncharacterized transporter C36.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P70196	TRAF6_MOUSE	TNF receptor-associated factor 6	15705807	Dependence of self-tolerance on TRAF6-directed development of thymic stroma.

Q9FMY5	U2AFB_ARATH	Splicing factor U2af small subunit B	16407443	Molecular characterization and phylogeny of U2AF35 homologs in plants.

P55060	XPO2_HUMAN	Exportin-2	7479798	Cloning and characterization of a cellular apoptosis susceptibility gene, the human homologue to the yeast chromosome segregation gene CSE1.

P87108	TIM10_YEAST	Mitochondrial import inner membrane translocase subunit TIM10	11483513	Functional reconstitution of the import of the yeast ADP/ATP carrier mediated by the TIM10 complex.

P40559	INP51_YEAST	Inositol-1,4,5-trisphosphate 5-phosphatase 1	9560389	Identification and characterization of an essential family of inositol polyphosphate 5-phosphatases (INP51, INP52 and INP53 gene products) in the yeast Saccharomyces cerevisiae.

Q9USU3	FBH1_SCHPO	F-box DNA helicase protein 1	16135799	Role of the Schizosaccharomyces pombe F-Box DNA helicase in processing recombination intermediates.

Q8R426	KCIP1_RAT	Kv channel-interacting protein 1	14980206	Structural insights into the functional interaction of KChIP1 with Shal-type K(+) channels.

Q3LH63	DMRT1_XENLA	Doublesex- and mab-3-related transcription factor 1	17118014	Expression and promoter analysis of Xenopus DMRT1 and functional characterization of the transactivation property of its protein.

P35631	AP1_ARATH	Floral homeotic protein APETALA 1	17428825	Specification of Arabidopsis floral meristem identity by repression of flowering time genes.

P09006	SPA3N_RAT	Serine protease inhibitor A3N	1694763	Molecular characterization of three rat liver serine-protease inhibitors affected by inflammation and hypophysectomy. Protein and mRNA analysis and cDNA cloning.

O33247	DOP_MYCTU	Pup deamidase/depupylase	19448618	Bacterial ubiquitin-like modifier Pup is deamidated and conjugated to substrates by distinct but homologous enzymes.

O13757	YF27_SCHPO	Meiotic chromosome segregation protein C17A2.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9QYK3	NRBF2_RAT	Nuclear receptor-binding factor 2	10786636	Nuclear receptor binding factor-2 (NRBF-2), a possible gene activator protein interacting with nuclear hormone receptors.

Q9SAD4	ESR1_ARATH	Ethylene-responsive transcription factor ESR1	17376809	The AP2 transcription factors DORNROSCHEN and DORNROSCHEN-LIKE redundantly control Arabidopsis embryo patterning via interaction with PHAVOLUTA.

Q9WU78	PDC6I_MOUSE	Programmed cell death 6-interacting protein	10200558	Alix, a novel mouse protein undergoing calcium-dependent interaction with the apoptotsis-linked-gene 2 (ALG-2) protein.

Q02930	CREB5_HUMAN	Cyclic AMP-responsive element-binding protein 5	8440710	Isolation and characterization of a novel member of the gene family encoding the cAMP response element-binding protein CRE-BP1.

Q99K82	SMOX_MOUSE	Spermine oxidase	12141946	Identification and characterization of a novel flavin-containing spermine oxidase of mammalian cell origin.

P00522	ABL_DROME	Tyrosine-protein kinase Abl	11756472	Abelson kinase regulates epithelial morphogenesis in Drosophila.

Q39023	MPK3_ARATH	Mitogen-activated protein kinase 3	12220631	Different protein kinase families are activated by osmotic stresses in Arabidopsis thaliana cell suspensions. Involvement of the MAP kinases AtMPK3 and AtMPK6.

O14279	RR14N_SCHPO	Ribosomal RNA-processing protein 14-N	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q08002	SHPI_STAHY	Neutral metalloprotease	8121397	Genetic and biochemical properties of an extracellular neutral metalloprotease from Staphylococcus hyicus subsp. hyicus.

P38418	LOX2_ARATH	Lipoxygenase 2, chloroplastic	17313166	The role of pectate lyase and the jasmonic acid defense response in Pseudomonas viridiflava virulence.

Q24352	GBRAL_DROME	Gamma-aminobutyric acid receptor alpha-like	15148245	Drosophila melanogaster GRD and LCCH3 subunits form heteromultimeric GABA-gated cation channels.

P23965	D3D2_RAT	3,2-trans-enoyl-CoA isomerase, mitochondrial	1958319	Mitochondrial 3-2trans-Enoyl-CoA isomerase. Purification, cloning, expression, and mitochondrial import of the key enzyme of unsaturated fatty acid beta-oxidation.

O15554	KCNN4_HUMAN	Intermediate conductance calcium-activated potassium channel protein 4	9380751	hSK4, a member of a novel subfamily of calcium-activated potassium channels.

P24487	ATPA_SCHPO	ATP synthase subunit alpha, mitochondrial	1824697	Alpha subunit of mitochondrial F1-ATPase from the fission yeast. Deduced sequence of the wild type and identification of a mutation that alters apparent negative cooperativity.

Q12879	NMDE1_HUMAN	Glutamate [NMDA] receptor subunit epsilon-1	8768735	Cloning and functional characterization of human heteromeric N- methyl-D-aspartate receptors.

Q0WNX9	KRP6_ARATH	Cyclin-dependent kinase inhibitor 6	18948957	Control of plant germline proliferation by SCF(FBL17) degradation of cell cycle inhibitors.

P47811	MK14_MOUSE	Mitogen-activated protein kinase 14	7914033	A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells.

Q9V3B7	PGSC1_DROME	Peptidoglycan-recognition protein SC1a/b	12496260	A scavenger function for a Drosophila peptidoglycan recognition protein.

Q8C460	ERI3_MOUSE	ERI1 exoribonuclease 3	11571277	PrPC directly interacts with proteins involved in signaling pathways.

Q39023	MPK3_ARATH	Mitogen-activated protein kinase 3	10717008	Functional analysis of oxidative stress-activated mitogen-activated protein kinase cascade in plants.

P52917	VPS4_YEAST	Vacuolar protein sorting-associated protein 4	9606181	The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function.

Q9LDU5	TI11A_ARATH	Protein TIFY 11A	17637677	JAZ repressor proteins are targets of the SCF(COI1) complex during jasmonate signalling.

P10080	SSBP1_YEAST	Single-stranded nucleic acid-binding protein	2823109	Saccharomyces cerevisiae SSB1 protein and its relationship to nucleolar RNA-binding proteins.

Q8RWN7	P2C32_ARATH	Protein phosphatase 2C 32	10725242	POLTERGEIST functions to regulate meristem development downstream of the CLAVATA loci.

Q10225	BTB3_SCHPO	BTB/POZ domain-containing protein 3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8L7G0	ARFA_ARATH	Auxin response factor 1	10476078	Dimerization and DNA binding of auxin response factors.

P23501	DS1P2_YEAST	Dihydrosphingosine 1-phosphate phosphatase YSR3	10563329	Yeast sphingosine-1-phosphate phosphatases: assay, expression, deletion, purification, and cellular localization by GFP tagging.

P83741	WNK1_MOUSE	Serine/threonine-protein kinase WNK1	11498583	Human hypertension caused by mutations in WNK kinases.

P40189	IL6RB_HUMAN	Interleukin-6 receptor subunit beta	11251120	Structure of an extracellular gp130 cytokine receptor signaling complex.

Q792S6	BOK_RAT	Bcl-2-related ovarian killer protein	9356461	Bok is a pro-apoptotic Bcl-2 protein with restricted expression in reproductive tissues and heterodimerizes with selective anti-apoptotic Bcl-2 family members.

P41889	CUT9_SCHPO	Anaphase-promoting complex subunit cut9	9264466	Distinct subunit functions and cell cycle regulated phosphorylation of 20S APC/cyclosome required for anaphase in fission yeast.

Q9H9Q4	NHEJ1_HUMAN	Non-homologous end-joining factor 1	16439205	XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining.

Q5BJF2	TMM97_HUMAN	Transmembrane protein 97	7694637	Identification and characterization of genes differentially expressed in meningiomas.

Q6RFY2	PHAR3_RAT	Phosphatase and actin regulator 3	15107502	Phactrs 1-4: a family of protein phosphatase 1 and actin regulatory proteins.

Q12406	ARP7_YEAST	Actin-related protein 7	12805231	The nuclear actin-related proteins Arp7 and Arp9: a dimeric module that cooperates with architectural proteins for chromatin remodeling.

Q24008	INAD_DROME	Inactivation-no-after-potential D protein	8630257	Regulation of the TRP Ca2+ channel by INAD in Drosophila photoreceptors.

Q24168	ORC2_DROME	Origin recognition complex subunit 2	11137005	Aberrant replication timing induces defective chromosome condensation in Drosophila ORC2 mutants.

Q08816	YO352_YEAST	Uncharacterized protein YOR352W	14562095	Global analysis of protein localization in budding yeast.

O43281	EFS_HUMAN	Embryonal Fyn-associated substrate	9349509	Identification of an Efs isoform that lacks the SH3 domain and chromosomal mapping of human Efs.

P39676	FHP_YEAST	Flavohemoprotein	9545281	Flavohemoglobin expression and function in Saccharomyces cerevisiae. No relationship with respiration and complex response to oxidative stress.

P98078	DAB2_MOUSE	Disabled homolog 2	15596140	Cloning and characterization of mouse disabled 2-interacting protein 2, a mouse orthologue of human NOSTRIN.

P35155	SCPB_BACSU	Segregation and condensation protein B	12065423	Cell cycle-dependent localization of two novel prokaryotic chromosome segregation and condensation proteins in Bacillus subtilis that interact with SMC protein.

Q9VTJ4	FUCO_DROME	Putative alpha-L-fucosidase	11698403	Composition of Drosophila melanogaster proteome involved in fucosylated glycan metabolism.

O13619	YHI3_SCHPO	Uncharacterized protein P22H7.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8C8R3	ANK2_MOUSE	Ankyrin-2	15262991	Ankyrin-B targets beta2-spectrin to an intracellular compartment in neonatal cardiomyocytes.

P34121	COAA_DICDI	Coactosin	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q811U4	MFN1_MOUSE	Mitofusin-1	12527753	Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development.

B0BK71	MSP1_MARSO	Peroxidase 1	18038130	Novel peroxidases of Marasmius scorodonius degrade beta-carotene.

Q50L39	BI52A_XENLA	Baculoviral IAP repeat-containing protein 5.2-A	16759290	Survivin increased vascular development during Xenopus ontogenesis.

Q14493	SLBP_HUMAN	Histone RNA hairpin-binding protein	15829567	Nuclear import of the stem-loop binding protein and localization during the cell cycle.

Q9FHW7	SKP1B_ARATH	SKP1-like protein 1B	12795696	Protein interaction analysis of SCF ubiquitin E3 ligase subunits from Arabidopsis.

Q9UMW8	UBP18_HUMAN	Ubl carboxyl-terminal hydrolase 18	10777664	Cloning and characterization of a novel human ubiquitin-specific protease, a homologue of murine UBP43 (Usp18).

Q9EPN1	NBEA_MOUSE	Neurobeachin	11102458	Neurobeachin: a protein kinase A-anchoring, beige/Chediak-Higashi protein homolog implicated in neuronal membrane traffic.

Q6ZSZ5	ARHGI_HUMAN	Rho guanine nucleotide exchange factor 18	14512443	G Protein betagamma subunits stimulate p114RhoGEF, a guanine nucleotide exchange factor for RhoA and Rac1: regulation of cell shape and reactive oxygen species production.

P84249	H33_DROME	Histone H3.3	7557364	Structure and expression of histone H3.3 genes in Drosophila melanogaster and Drosophila hydei.

Q03862	ARX1_YEAST	Probable metalloprotease ARX1	12374754	60S pre-ribosome formation viewed from assembly in the nucleolus until export to the cytoplasm.

Q14526	HIC1_HUMAN	Hypermethylated in cancer 1 protein	7585125	p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3.

Q12743	DFM1_YEAST	DER1-like family member protein 1	15093775	Der1p, a protein required for degradation of malfolded soluble proteins of the endoplasmic reticulum: topology and Der1-like proteins.

Q02795	OSTD_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit SWP1	16297388	Yeast oligosaccharyltransferase consists of two functionally distinct sub-complexes, specified by either the Ost3p or Ost6p subunit.

Q9Y7Z8	MYO1_SCHPO	Myosin-1	16087707	Interactions of WASp, myosin-I, and verprolin with Arp2/3 complex during actin patch assembly in fission yeast.

P32478	HS150_YEAST	Cell wall mannoprotein HSP150	9192695	Stress proteins on the yeast cell surface determine resistance to osmotin, a plant antifungal protein.

Q9UQ52	CNTN6_HUMAN	Contactin-6	9486763	cDNA cloning and chromosomal localization of neural adhesion molecule, NB-3 in human.

P53914	KRE33_YEAST	UPF0202 protein KRE33	14562095	Global analysis of protein localization in budding yeast.

Q9W349	LOZEN_DROME	Protein lozenge	8675007	Patterning of cells in the Drosophila eye by Lozenge, which shares homologous domains with AML1.

P26358	DNMT1_HUMAN	DNA (cytosine-5)-methyltransferase 1	10888872	DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci.

O43157	PLXB1_HUMAN	Plexin-B1	12730235	Direct interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF- mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cells.

Q9Z2I7	SVOP_RAT	Synaptic vesicle 2-related protein	9801366	SVOP, an evolutionarily conserved synaptic vesicle protein, suggests novel transport functions of synaptic vesicles.

Q86VD1	MORC1_HUMAN	MORC family CW-type zinc finger protein 1	10369865	New gene family defined by MORC, a nuclear protein required for mouse spermatogenesis.

P15919	RAG1_MOUSE	V(D)J recombination-activating protein 1	10601033	Mutations of acidic residues in RAG1 define the active site of the V(D)J recombinase.

Q8CH87	GCNT3_RAT	Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3	12626393	Purification and cDNA cloning of UDP-GlcNAc:GlcNAcbeta1-3Galbeta1- 4Glc(NAc)-R [GlcNAc to Gal]beta1,6N-acetylglucosaminyltransferase from rat small intestine: a major carrier of dIGnT activity in rat small intestine.

P50452	SPB8_HUMAN	Serpin B8	8530382	Molecular cloning, expression, and partial characterization of two novel members of the ovalbumin family of serine proteinase inhibitors.

P00747	PLMN_HUMAN	Plasminogen	6216475	Plasminogen Tochigi: inactive plasmin resulting from replacement of alanine-600 by threonine in the active site.

Q9UBX1	CATF_HUMAN	Cathepsin F	9822672	Human cathepsin F. Molecular cloning, functional expression, tissue localization, and enzymatic characterization.

Q99N50	SYTL2_MOUSE	Synaptotagmin-like protein 2	16716193	Decreased basal mucus secretion by Slp2-a-deficient gastric surface mucous cells.

O14668	TMG1_HUMAN	Transmembrane gamma-carboxyglutamic acid protein 1	9256434	Primary structure and tissue distribution of two novel proline-rich gamma-carboxyglutamic acid proteins.

P36632	RAD26_SCHPO	DNA repair protein rad26	8019001	Identification and characterization of new elements involved in checkpoint and feedback controls in fission yeast.

O94676	UTP22_SCHPO	U3 small nucleolar RNA-associated protein 22	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q09898	SID2_SCHPO	Serine/threonine-protein kinase sid2	10459013	Sid2p, a spindle pole body kinase that regulates the onset of cytokinesis.

Q84VX3	ALF4_ARATH	Aberrant root formation protein 4	14731255	Arabidopsis ALF4 encodes a nuclear-localized protein required for lateral root formation.

Q9SJ10	CADH3_ARATH	Cinnamyl alcohol dehydrogenase 3	14745009	Functional reclassification of the putative cinnamyl alcohol dehydrogenase multigene family in Arabidopsis.

Q99748	NRTN_HUMAN	Neurturin	8945474	Neurturin, a relative of glial-cell-line-derived neurotrophic factor.

P32339	HMX1_YEAST	Heme-binding protein HMX1	11566881	Sorting of proteins into multivesicular bodies: ubiquitin-dependent and -independent targeting.

O94532	FOR3_SCHPO	Formin-3	11696322	Roles of the fission yeast formin for3p in cell polarity, actin cable formation and symmetric cell division.

O15120	PLCB_HUMAN	1-acyl-sn-glycerol-3-phosphate acyltransferase beta	9242711	Human lysophosphatidic acid acyltransferase. cDNA cloning, expression, and localization to chromosome 9q34.3.

O48963	PHOT1_ARATH	Phototropin-1	9405347	Arabidopsis NPH1: a protein kinase with a putative redox-sensing domain.

P07307	ASGR2_HUMAN	Asialoglycoprotein receptor 2	11543633	Cloning, mapping, and characterization of a human homologue of the yeast longevity assurance gene LAG1.

P49747	COMP_HUMAN	Cartilage oligomeric matrix protein	10852928	Cartilage oligomeric matrix protein is a calcium-binding protein, and a mutation in its type 3 repeats causes conformational changes.

Q06488	RSC2_YEAST	Chromatin structure-remodeling complex subunit RSC2	12183366	Chromatin remodeling by RSC involves ATP-dependent DNA translocation.

P38110	ATM_YEAST	Serine/threonine-protein kinase TEL1	11095737	Protein kinase activity of Tel1p and Mec1p, two Saccharomyces cerevisiae proteins related to the human ATM protein kinase.

Q90417	RXRBB_DANRE	Retinoic acid receptor RXR-beta-B	7565671	New retinoid X receptor subtypes in zebra fish (Danio rerio) differentially modulate transcription and do not bind 9-cis retinoic acid.

Q9Y091	FL2D_DROME	Pre-mRNA-splicing regulator female-lethal(2)D	10101174	Trans-acting factors required for inclusion of regulated exons in the Ultrabithorax mRNAs of Drosophila melanogaster.

P50947	PHO23_YEAST	Transcriptional regulatory protein PHO23	16286008	Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex.

P15702	LEUK_MOUSE	Leukosialin	11728336	ERM-dependent movement of CD43 defines a novel protein complex distal to the immunological synapse.

Q9WVC8	S26A3_MOUSE	Chloride anion exchanger	10428871	Mouse down-regulated in adenoma (DRA) is an intestinal Cl(-)/HCO(3)(-) exchanger and is up-regulated in colon of mice lacking the NHE3 Na(+)/H(+) exchanger.

P25336	MSH3_YEAST	DNA mismatch repair protein MSH3	8805366	Binding of insertion/deletion DNA mismatches by the heterodimer of yeast mismatch repair proteins MSH2 and MSH3.

P14120	RL30_YEAST	60S ribosomal protein L30	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q91392	RARGA_DANRE	Retinoic acid receptor gamma-A	7565671	New retinoid X receptor subtypes in zebra fish (Danio rerio) differentially modulate transcription and do not bind 9-cis retinoic acid.

P70178	SIX5_MOUSE	Homeobox protein SIX5	8814301	Identification and expression of Six family genes in mouse retina.

Q9SZF7	SHR_ARATH	Protein SHORT-ROOT	17785527	Arabidopsis JACKDAW and MAGPIE zinc finger proteins delimit asymmetric cell division and stabilize tissue boundaries by restricting SHORT-ROOT action.

O43078	SUR2_SCHPO	Protein sur2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UHK0	NUFP1_HUMAN	Nuclear fragile X mental retardation-interacting protein 1	10556305	A novel RNA-binding nuclear protein that interacts with the fragile X mental retardation (FMR1) protein.

O60218	AK1BA_HUMAN	Aldo-keto reductase family 1 member B10	9565553	Identification and characterization of a novel human aldose reductase-like gene.

P70060	LDB1_XENLA	LIM domain-binding protein 1	8918878	Interactions of the LIM-domain-binding factor Ldb1 with LIM homeodomain proteins.

Q9UKF2	ADA30_HUMAN	Disintegrin and metalloproteinase domain-containing protein 30	10512762	Isolation of two novel metalloproteinase-disintegrin (ADAM) cDNAs that show testis-specific gene expression.

Q26626	KIFA3_STRPU	Kinesin-associated protein 3	8636215	Sequence and submolecular localization of the 115-kD accessory subunit of the heterotrimeric kinesin-II (KRP85/95) complex.

P24941	CDK2_HUMAN	Cell division protein kinase 2	12839962	Human Spy1 promotes survival of mammalian cells following DNA damage.

Q9HB75	PIDD_HUMAN	Leucine-rich repeat and death domain-containing protein	10825539	LRDD, a novel leucine rich repeat and death domain containing protein.

O42261	IRX3_XENLA	Iroquois-class homeodomain protein irx-3	19268445	The Xenopus Irx genes are essential for neural patterning and define the border between prethalamus and thalamus through mutual antagonism with the anterior repressors Fezf and Arx.

O95456	PSMG1_HUMAN	Proteasome assembly chaperone 1	15670775	Molecular and cellular characterization of the Down syndrome critical region protein 2.

O60548	FOXD2_HUMAN	Forkhead box protein D2	9403061	Cloning and characterization of freac-9 (FKHL17), a novel kidney- expressed human forkhead gene that maps to chromosome 1p32-p34.

Q2TWM1	PELB_ASPOR	Pectin lyase 1	11272833	Sequence analysis and overexpression of a pectin lyase gene (pel1) from Aspergillus oryzae KBN616.

P53792	SC5A2_RAT	Sodium/glucose cotransporter 2	7493971	Molecular characteristics of Na(+)-coupled glucose transporters in adult and embryonic rat kidney.

Q14103	HNRPD_HUMAN	Heterogeneous nuclear ribonucleoprotein D0	8321232	Nuclear proteins that bind the pre-mRNA 3' splice site sequence r(UUAG/G) and the human telomeric DNA sequence d(TTAGGG)n.

Q5ASG9	PGLX1_EMENI	Exopolygalacturonase X-1	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

Q14554	PDIA5_HUMAN	Protein disulfide-isomerase A5	7556671	Molecular cloning of the cDNA encoding a novel protein disulfide isomerase-related protein (PDIR).

P63005	LIS1_MOUSE	Platelet-activating factor acetylhydrolase IB subunit alpha	11163259	A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system.

Q13253	NOGG_HUMAN	Noggin	12478285	Structural basis of BMP signalling inhibition by the cystine knot protein Noggin.

Q9C5X0	IAA34_ARATH	Auxin-responsive protein IAA34	12036262	Genetics of Aux/IAA and ARF action in plant growth and development.

Q12948	FOXC1_HUMAN	Forkhead box protein C1	15277473	The wing 2 region of the FOXC1 forkhead domain is necessary for normal DNA-binding and transactivation functions.

Q04089	DOT1_YEAST	Histone-lysine N-methyltransferase, H3 lysine-79 specific	12080090	Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association.

Q9FLW0	Y5241_ARATH	Probable receptor-like protein kinase At5g24010	17644812	A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome.

Q920G9	GMCL1_MOUSE	Germ cell-less protein-like 1	10727854	Identification of a mouse germ cell-less homologue with conserved activity in Drosophila.

O14842	FFAR1_HUMAN	Free fatty acid receptor 1	9344866	A cluster of four novel human G protein-coupled receptor genes occurring in close proximity to CD22 gene on chromosome 19q13.1.

P40065	MAM1_YEAST	Monopolin complex subunit MAM1	11470404	A screen for genes required for meiosis and spore formation based on whole-genome expression.

P83264	PRT1_SCOSC	Sperm protamine alpha isoform 1	9530815	Primary structure of scombrine alpha: two different species with an identical protamine.

O70481	UBR1_MOUSE	E3 ubiquitin-protein ligase UBR1	11689692	Construction and analysis of mouse strains lacking the ubiquitin ligase UBR1 (E3alpha) of the N-end rule pathway.

Q96BS2	TESC_HUMAN	Tescalcin	17717601	Tescalcin is an essential factor in megakaryocytic differentiation associated with Ets family gene expression.

Q14643	ITPR1_HUMAN	Inositol 1,4,5-trisphosphate receptor type 1	15652484	Subtype-specific and ER lumenal environment-dependent regulation of inositol 1,4,5-trisphosphate receptor type 1 by ERp44.

O43586	PPIP1_HUMAN	Proline-serine-threonine phosphatase-interacting protein 1	9857189	A cdc15-like adaptor protein (CD2BP1) interacts with the CD2 cytoplasmic domain and regulates CD2-triggered adhesion.

P49685	GPR15_HUMAN	G-protein coupled receptor 15	8838812	A novel human gene encoding a G-protein-coupled receptor (GPR15) is located on chromosome 3.

O35095	NCDN_RAT	Neurochondrin	9398642	A novel brain gene, norbin, induced by treatment of tetraethylammonium in rat hippocampal slice and accompanied with neurite-outgrowth in neuro 2a cells.

O15498	YKT6_HUMAN	Synaptobrevin homolog YKT6	15215310	Participation of the syntaxin 5/Ykt6/GS28/GS15 SNARE complex in transport from the early/recycling endosome to the trans-Golgi network.

P61407	TDRD6_MOUSE	Tudor domain-containing protein 6	17141210	Tudor-related proteins TDRD1/MTR-1, TDRD6 and TDRD7/TRAP: domain composition, intracellular localization, and function in male germ cells in mice.

Q8L5Y6	CAND1_ARATH	Cullin-associated NEDD8-dissociated protein 1	15208391	Arabidopsis CAND1, an unmodified CUL1-interacting protein, is involved in multiple developmental pathways controlled by ubiquitin/proteasome-mediated protein Degradation.

P16104	H2AX_HUMAN	Histone H2A.x	19234442	Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions.

Q8GX92	CHX6A_ARATH	Cation/H(+) antiporter 6A	11500563	Phylogenetic relationships within cation transporter families of Arabidopsis.

Q9P6M0	SLX4_SCHPO	Structure-specific endonuclease subunit slx4	16467377	Rad22Rad52-dependent repair of ribosomal DNA repeats cleaved by Slx1- Slx4 endonuclease.

P29590	PML_HUMAN	Probable transcription factor PML	7729428	The solution structure of the RING finger domain from the acute promyelocytic leukaemia proto-oncoprotein PML.

P17600	SYN1_HUMAN	Synapsin-1	2110562	The structure of the human synapsin I gene and protein.

Q20646	CEP1_CAEEL	Transcription factor cep-1	11696333	The C. elegans homolog of the p53 tumor suppressor is required for DNA damage-induced apoptosis.

Q8RY71	ESP_ARATH	Epithiospecifier protein	17369373	The antagonist function of Arabidopsis WRKY53 and ESR/ESP in leaf senescence is modulated by the jasmonic and salicylic acid equilibrium.

P22068	ATPB_SCHPO	ATP synthase subunit beta, mitochondrial	1831760	Beta subunit of mitochondrial F1-ATPase from the fission yeast. Deduced sequence of the wild type protein and identification of a mutation that increases nucleotide binding.

P16662	UD2B7_HUMAN	UDP-glucuronosyltransferase 2B7	2159463	Cloning and expression of human liver UDP-glucuronosyltransferase in COS-1 cells. 3,4-catechol estrogens and estriol as primary substrates.

Q64368	DAZL_MOUSE	Deleted in azoospermia-like	10903443	In vivo and in vitro analysis of homodimerisation activity of the mouse Dazl1 protein.

Q91WM1	STRBP_MOUSE	Spermatid perinuclear RNA-binding protein	11336498	Mice deficient for spermatid perinuclear RNA-binding protein show neurologic, spermatogenic, and sperm morphological abnormalities.

P32047	MLF3_YEAST	Protein MLF3	14562095	Global analysis of protein localization in budding yeast.

P04197	MYB_DROME	Myb protein	15545624	Identification of a Drosophila Myb-E2F2/RBF transcriptional repressor complex.

P81274	GPSM2_HUMAN	G-protein-signaling modulator 2	15632202	Direct binding of Lgl2 to LGN during mitosis and its requirement for normal cell division.

Q9UBG3	CRNN_HUMAN	Cornulin	11606197	The human oesophageal squamous epithelium exhibits a novel type of heat shock protein response.

Q9UHI6	DDX20_HUMAN	Probable ATP-dependent RNA helicase DDX20	10383418	Characterization of DP103, a novel DEAD box protein that binds to the Epstein-Barr virus nuclear proteins EBNA2 and EBNA3C.

Q9Z1P8	ANGL4_MOUSE	Angiopoietin-related protein 4	10862772	Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene.

Q6NLC8	Y1648_ARATH	Uncharacterized protein At1g66480	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P55163	GEX3_CAEEL	Membrane-associated protein gex-3	11877381	The GEX-2 and GEX-3 proteins are required for tissue morphogenesis and cell migrations in C. elegans.

P49908	SEPP1_HUMAN	Selenoprotein P	8421687	Conserved nucleotide sequences in the open reading frame and 3' untranslated region of selenoprotein P mRNA.

Q9VLA1	B3G2S_DROME	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase S	12511570	Identification and characterization of three Drosophila melanogaster glucuronyltransferases responsible for the synthesis of the conserved glycosaminoglycan-protein linkage region of proteoglycans: two novel homologs exhibit broad specificity toward oligosaccharides from proteoglycans, glycoproteins, and glycosphingolipids.

O43182	RHG06_HUMAN	Rho GTPase-activating protein 6	10699171	Functional analysis of ARHGAP6, a novel GTPase-activating protein for RhoA.

P33895	NUF2_YEAST	Kinetochore protein NUF2	11179222	The budding yeast proteins Spc24p and Spc25p interact with Ndc80p and Nuf2p at the kinetochore and are important for kinetochore clustering and checkpoint control.

Q10459	MOM2_CAEEL	Protein mom-2	9288750	Wnt signaling and an APC-related gene specify endoderm in early C. elegans embryos.

P48146	NPBW2_HUMAN	Neuropeptides B/W receptor type 2	12401809	Identification of natural ligands for the orphan G protein-coupled receptors GPR7 and GPR8.

Q9JIL4	NHRF3_MOUSE	Na(+)/H(+) exchange regulatory cofactor NHE-RF3	15523054	PDZK1 directly regulates the function of organic cation/carnitine transporter OCTN2.

Q9V6Q2	CID_DROME	Histone H3-like centromeric protein cid	16839185	Drosophila CENP-A mutations cause a BubR1-dependent early mitotic delay without normal localization of kinetochore components.

Q06704	IMH1_YEAST	Golgin IMH1	12620189	The ARF-like GTPases Arl1p and Arl3p act in a pathway that interacts with vesicle-tethering factors at the Golgi apparatus.

O43155	FLRT2_HUMAN	Leucine-rich repeat transmembrane protein FLRT2	10644439	Identification of FLRT1, FLRT2, and FLRT3: a novel family of transmembrane leucine-rich repeat proteins.

Q04002	SCC2_YEAST	Sister chromatid cohesion protein 2	10882066	Cohesin's binding to chromosomes depends on a separate complex consisting of Scc2 and Scc4 proteins.

P08034	CXB1_HUMAN	Gap junction beta-1 protein	2875078	Cloning and characterization of human and rat liver cDNAs coding for a gap junction protein.

A1Z9E2	LIN54_DROME	Protein lin-54 homolog	15545624	Identification of a Drosophila Myb-E2F2/RBF transcriptional repressor complex.

O48963	PHOT1_ARATH	Phototropin-1	18585389	Structural basis of the LOV1 dimerization of Arabidopsis phototropins 1 and 2.

Q24256	BARH2_DROME	Homeobox protein B-H2	10648235	Formation and specification of distal leg segments in Drosophila by dual Bar homeobox genes, BarH1 and BarH2.

Q9R010	CIB1_RAT	Calcium and integrin-binding protein 1	10523297	The polo-like protein kinases Fnk and Snk associate with a Ca(2+)- and integrin-binding protein and are regulated dynamically with synaptic plasticity.

P43404	ZAP70_MOUSE	Tyrosine-protein kinase ZAP-70	17028588	RhoH GTPase recruits and activates Zap70 required for T cell receptor signaling and thymocyte development.

P21463	TSHR_RAT	Thyrotropin receptor	1696008	Cloning, chromosomal assignment, and regulation of the rat thyrotropin receptor: expression of the gene is regulated by thyrotropin, agents that increase cAMP levels, and thyroid autoantibodies.

O60443	DFNA5_HUMAN	Non-syndromic hearing impairment protein 5	9771715	Nonsyndromic hearing impairment is associated with a mutation in DFNA5.

P97431	IRF6_MOUSE	Interferon regulatory factor 6	19036739	Missense mutations that cause Van der Woude syndrome and popliteal pterygium syndrome affect the DNA-binding and transcriptional activation functions of IRF6.

Q02747	GUC2A_HUMAN	Guanylin	7947768	Determination of the solution structure of the peptide hormone guanylin: observation of a novel form of topological stereoisomerism.

Q02784	GLRX5_YEAST	Monothiol glutaredoxin-5, mitochondrial	12730244	Biochemical characterization of yeast mitochondrial Grx5 monothiol glutaredoxin.

O74887	TSA1_SCHPO	Peroxiredoxin tpx1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P48544	IRK5_HUMAN	G protein-activated inward rectifier potassium channel 4	8834003	Functional characterization and localization of a cardiac-type inwardly rectifying K+ channel.

O55005	ROBO1_RAT	Roundabout homolog 1	11754167	Spatiotemporal expression patterns of slit and robo genes in the rat brain.

O95918	OR2H2_HUMAN	Olfactory receptor 2H2	7665158	Olfactory receptor-like genes are located in the human major histocompatibility complex.

P53730	ALG12_YEAST	Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase	14562095	Global analysis of protein localization in budding yeast.

Q9UBB9	TFP11_HUMAN	Tuftelin-interacting protein 11	11991638	Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.

P51959	CCNG1_HUMAN	Cyclin-G1	8626390	Cyclin G1 and cyclin G2 comprise a new family of cyclins with contrasting tissue-specific and cell cycle-regulated expression.

P25398	RS12_HUMAN	40S ribosomal protein S12	1861993	cDNA and predicted amino acid sequences of the human ribosomal protein genes rpS12 and rpL17.

Q96G27	WBP1_HUMAN	WW domain-binding protein 1	15064722	WWOX binds the specific proline-rich ligand PPXY: identification of candidate interacting proteins.

P39929	SNF7_YEAST	Vacuolar-sorting protein SNF7	12194857	Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting.

P49023	PAXI_HUMAN	Paxillin	12861019	RNF5, a RING finger protein that regulates cell motility by targeting paxillin ubiquitination and altered localization.

P08235	MCR_HUMAN	Mineralocorticoid receptor	9662404	Mutations in the mineralocorticoid receptor gene cause autosomal dominant pseudohypoaldosteronism type I.

Q86JM7	P2XA_DICDI	P2X receptor A	19833731	Functional characterization of intracellular Dictyostelium discoideum P2X receptors.

Q9UW14	PACC_CANAL	pH-response transcription factor pacC/RIM101	10601210	Effect of environmental pH on morphological development of Candida albicans is mediated via the PacC-related transcription factor encoded by PRR2.

Q07807	PUF3_YEAST	mRNA-binding protein PUF3	18523582	Yeast mitochondrial biogenesis: a role for the PUF RNA-binding protein Puf3p in mRNA localization.

P25067	CO8A2_HUMAN	Collagen alpha-2(VIII) chain	2019595	The alpha 2(VIII) collagen gene. A novel member of the short chain collagen family located on the human chromosome 1.

Q5C9Z4	NOM1_HUMAN	Nucleolar MIF4G domain-containing protein 1	15715967	Identification of NOM1, a nucleolar, eIF4A binding protein encoded within the chromosome 7q36 breakpoint region targeted in cases of pediatric acute myeloid leukemia.

Q9CWE6	OOEP_MOUSE	Oocyte-expressed protein homolog	18804437	A subcortical maternal complex essential for preimplantation mouse embryogenesis.

Q76NT9	ACCO1_DICDI	1-aminocyclopropane-1-carboxylate oxidase	17499244	Ethylene induces zygote formation through an enhanced expression of zyg1 in Dictyostelium mucoroides.

Q24324	DSOR1_DROME	Dual specificity mitogen-activated protein kinase kinase dSOR1	8381718	A protein kinase similar to MAP kinase activator acts downstream of the raf kinase in Drosophila.

P01160	ANF_HUMAN	Atrial natriuretic factor	1660465	Extracellular domain-IgG fusion proteins for three human natriuretic peptide receptors. Hormone pharmacology and application to solid phase screening of synthetic peptide antisera.

O14194	GGT2_SCHPO	Gamma-glutamyltranspeptidase 2	15920625	Characterization of a second gene encoding gamma-glutamyl transpeptidase from Schizosaccharomyces pombe.

O94760	DDAH1_HUMAN	N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	9874257	Purification, cDNA cloning and expression of human NG,NG- dimethylarginine dimethylaminohydrolase.

P56976	BLR_ECOLI	Beta-lactam resistance protein	10931331	'Intergenic' blr gene in Escherichia coli encodes a 41-residue membrane protein affecting intrinsic susceptibility to certain inhibitors of peptidoglycan synthesis.

P06737	PYGL_HUMAN	Glycogen phosphorylase, liver form	12204691	Structure-activity analysis of the purine binding site of human liver glycogen phosphorylase.

Q8IZX4	TAF1L_HUMAN	Transcription initiation factor TFIID subunit 1-like	12217962	Functional substitution for TAF(II)250 by a retroposed homolog that is expressed in human spermatogenesis.

P27038	AVR2A_MOUSE	Activin receptor type-2A	1646080	Expression cloning of an activin receptor, a predicted transmembrane serine kinase.

Q9UMR2	DD19B_HUMAN	ATP-dependent RNA helicase DDX19B	10428971	Dbp5, a DEAD-box protein required for mRNA export, is recruited to the cytoplasmic fibrils of nuclear pore complex via a conserved interaction with CAN/Nup159p.

P60716	LIPA_ECOLI	Lipoyl synthase	8444795	Lipoic acid metabolism in Escherichia coli: sequencing and functional characterization of the lipA and lipB genes.

P53915	NRK1_YEAST	Nicotinamide riboside kinase	15137942	Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans.

O76015	KRT38_HUMAN	Keratin, type I cuticular Ha8	9756910	Characterization of a 190-kilobase pair domain of human type I hair keratin genes.

O95232	LC7L3_HUMAN	Luc7-like protein 3	12565863	Effect of cisplatin treatment on speckled distribution of a serine/arginine-rich nuclear protein CROP/Luc7A.

P32354	MCM10_YEAST	Minichromosome maintenance protein 10	16328881	Dual roles for Mcm10 in DNA replication initiation and silencing at the mating-type loci.

Q9NR28	DBLOH_HUMAN	Diablo homolog, mitochondrial	10929711	Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition.

Q93062	RBPMS_HUMAN	RNA-binding protein with multiple splicing	8855282	A unique human gene that spans over 230 kb in the human chromosome 8p11-12 and codes multiple family proteins sharing RNA-binding motifs.

Q63ZW7	INADL_MOUSE	InaD-like protein	9647694	CIPP, a novel multivalent PDZ domain protein, selectively interacts with Kir4.0 family members, NMDA receptor subunits, neurexins, and neuroligins.

P42095	RECO_BACSU	DNA repair protein recO	15186413	Visualization of DNA double-strand break repair in live bacteria reveals dynamic recruitment of Bacillus subtilis RecF, RecO and RecN proteins to distinct sites on the nucleoids.

O43157	PLXB1_HUMAN	Plexin-B1	15184888	Interplay between scatter factor receptors and B plexins controls invasive growth.

P53667	LIMK1_HUMAN	LIM domain kinase 1	8689688	LIM-kinase1 hemizygosity implicated in impaired visuospatial constructive cognition.

P37088	SCNNA_HUMAN	Amiloride-sensitive sodium channel subunit alpha	11244092	The Nedd4-like protein KIAA0439 is a potential regulator of the epithelial sodium channel.

P01742	HV101_HUMAN	Ig heavy chain V-I region EU	5489771	The covalent structure of a human gamma G-immunoglobulin. VII. Amino acid sequence of heavy-chain cyanogen bromide fragments H1-H4.

Q14103	HNRPD_HUMAN	Heterogeneous nuclear ribonucleoprotein D0	1433497	Identification and cloning of a novel heterogeneous nuclear ribonucleoprotein C-like protein that functions as a transcriptional activator of the hepatitis B virus enhancer II.

Q6PAL1	DRAXI_MOUSE	Draxin	19857465	Neucrin is a novel neural-specific secreted antagonist to canonical Wnt signaling.

Q9JLJ3	AL9A1_RAT	4-trimethylaminobutyraldehyde dehydrogenase	10702312	Molecular and biochemical characterization of rat gamma- trimethylaminobutyraldehyde dehydrogenase and evidence for the involvement of human aldehyde dehydrogenase 9 in carnitine biosynthesis.

Q9NQC7	CYLD_HUMAN	Ubiquitin carboxyl-terminal hydrolase CYLD	20194890	CYLD regulates angiogenesis by mediating vascular endothelial cell migration.

Q99607	ELF4_HUMAN	ETS-related transcription factor Elf-4	10207087	Functional and physical interactions between AML1 proteins and an ETS protein, MEF: implications for the pathogenesis of t(8;21)-positive leukemias.

Q9NPF7	IL23A_HUMAN	Interleukin-23 subunit alpha	11114383	Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12.

Q00532	CDKL1_HUMAN	Cyclin-dependent kinase-like 1	1639063	A family of human cdc2-related protein kinases.

P48739	PIPNB_HUMAN	Phosphatidylinositol transfer protein beta isoform	8541325	Cloning and expression of human cDNA encoding phosphatidylinositol transfer protein beta.

Q10905	CRN4_CAEEL	Cell death-related nuclease 4	12718884	Functional genomic analysis of apoptotic DNA degradation in C. elegans.

Q84Y95	GRS14_ARATH	Monothiol glutaredoxin-S14, chloroplastic	12480930	Cloning and characterization of CXIP1 A novel PICOT domain-containing Arabidopsis protein that associates with CAX1.

O43488	ARK72_HUMAN	Aflatoxin B1 aldehyde reductase member 2	9576847	Molecular cloning, expression and catalytic activity of a human AKR7 member of the aldo-keto reductase superfamily: evidence that the major 2-carboxybenzaldehyde reductase from human liver is a homologue of rat aflatoxin B1-aldehyde reductase.

Q9C5V6	TOP6B_ARATH	DNA topoisomerase 6 subunit B	11410368	Molecular characterization of homologues of both subunits A (SPO11) and B of the archaebacterial topoisomerase 6 in plants.

B3DNN5	CDC16_ARATH	Anaphase-promoting complex subunit 6	19336465	The APC/C E3 ligase remains active in most post-mitotic Arabidopsis cells and is required for proper vasculature development and organization.

P01567	IFNA7_HUMAN	Interferon alpha-7	2995168	Cloning, expression and biological activity of a new variant of human interferon alpha identified in virus induced lymphoblastoid cells.

P32843	YME2_YEAST	Mitochondrial escape protein 2	8649384	Inactivation of YME2/RNA12, which encodes an integral inner mitochondrial membrane protein, causes increased escape of DNA from mitochondria to the nucleus in Saccharomyces cerevisiae.

Q66H98	SDPR_RAT	Serum deprivation-response protein	9566962	Targeting of protein kinase Calpha to caveolae.

Q91YI1	ATG13_MOUSE	Autophagy-related protein 13	19211835	Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy.

O60733	PA2G6_HUMAN	85 kDa calcium-independent phospholipase A2	19164547	Role of calcium-independent phospholipase A2 in the pathogenesis of Barth syndrome.

O60936	NOL3_HUMAN	Nucleolar protein 3	9560245	ARC, an inhibitor of apoptosis expressed in skeletal muscle and heart that interacts selectively with caspases.

Q9NRM7	LATS2_HUMAN	Serine/threonine-protein kinase LATS2	10673337	Structure, expression, and chromosome mapping of LATS2, a mammalian homologue of the Drosophila tumor suppressor gene lats/warts.

P86171	VSPK1_GLOUS	Kinin-releasing enzyme KR-E-1	3201479	Purification of a kininogenase from the venom of Agkistrodon caliginosus (Kankoku-Mamushi).

Q9EPB1	DPP2_RAT	Dipeptidyl peptidase 2	11173530	Purification, molecular cloning, and immunohistochemical localization of dipeptidyl peptidase II from the rat kidney and its identity with quiescent cell proline dipeptidase.

Q9P7X9	YH66_SCHPO	Uncharacterized mitochondrial carrier P23A10.06	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P35052	GPC1_HUMAN	Glypican-1	2148568	Molecular cloning of a phosphatidylinositol-anchored membrane heparan sulfate proteoglycan from human lung fibroblasts.

P10145	IL8_HUMAN	Interleukin-8	2007144	Chemical synthesis, purification, and characterization of two inflammatory proteins, neutrophil activating peptide 1 (interleukin-8) and neutrophil activating peptide.

O43684	BUB3_HUMAN	Mitotic checkpoint protein BUB3	15525512	Phosphorylation of Cdc20 by Bub1 provides a catalytic mechanism for APC/C inhibition by the spindle checkpoint.

O75694	NU155_HUMAN	Nuclear pore complex protein Nup155	10191094	Localization of a human nucleoporin 155 gene (NUP155) to the 5p13 region and cloning of its cDNA.

P47108	URB2_YEAST	Nucleolar pre-ribosomal-associated protein 2	15242642	Exploration of essential gene functions via titratable promoter alleles.

P92939	ECA1_ARATH	Calcium-transporting ATPase 1, endoplasmic reticulum-type	9238019	ECA1 complements yeast mutants defective in Ca2+ pumps and encodes an endoplasmic reticulum-type Ca2+-ATPase in Arabidopsis thaliana.

Q16322	KCA10_HUMAN	Potassium voltage-gated channel subfamily A member 10	9177773	Genomic localization of the human gene for KCNA10, a cGMP-activated K channel.

Q39821	SDLCA_SOYBN	Dynamin-related protein 12A	11283335	A novel UDP-glucose transferase is part of the callose synthase complex and interacts with phragmoplastin at the forming cell plate.

P52917	VPS4_YEAST	Vacuolar protein sorting-associated protein 4	12953057	Vps20p and Vta1p interact with Vps4p and function in multivesicular body sorting and endosomal transport in Saccharomyces cerevisiae.

Q69VD5	PNH1_ORYSJ	Protein argonaute PNH1	12000455	OsPNH1 regulates leaf development and maintenance of the shoot apical meristem in rice.

Q9LJU0	CBL10_ARATH	COBRA-like protein 10	12376623	The COBRA family of putative GPI-anchored proteins in Arabidopsis. A new fellowship in expansion.

P36630	CG22_SCHPO	G2/mitotic-specific cyclin cig2	8455610	Two fission yeast B-type cyclins, cig2 and Cdc13, have different functions in mitosis.

Q8T638	DMTA_DICDI	Des-methyl DIF-1 methyltransferase A	11163223	The role of DIF-1 signaling in Dictyostelium development.

Q05084	ICA69_HUMAN	Islet cell autoantigen 1	8326004	Islet cell autoantigen 69 kD (ICA69). Molecular cloning and characterization of a novel diabetes-associated autoantigen.

P18754	RCC1_HUMAN	Regulator of chromosome condensation	16820410	Novel function of beta-arrestin2 in the nucleus of mature spermatozoa.

O94643	MIS17_SCHPO	Kinetochore protein mis17	15369671	Mis16 and Mis18 are required for CENP-A loading and histone deacetylation at centromeres.

Q00246	RHO4_YEAST	GTP-binding protein RHO4	1448099	Yeast RHO3 and RHO4 ras superfamily genes are necessary for bud growth, and their defect is suppressed by a high dose of bud formation genes CDC42 and BEM1.

P85054	ES1SB_RANSV	Esculentin-1SEb	16386333	Histamine-releasing and antimicrobial peptides from the skin secretions of the dusky gopher frog, Rana sevosa.

Q99K74	MED24_MOUSE	Mediator of RNA polymerase II transcription subunit 24	12093747	The TRAP100 component of the TRAP/Mediator complex is essential in broad transcriptional events and development.

O75223	GGCT_HUMAN	Gamma-glutamylcyclotransferase	17932939	Crystal structure of Homo sapiens protein LOC79017.

P25940	CO5A3_HUMAN	Collagen alpha-3(V) chain	10722718	The pro-alpha3 (V) collagen chain. Complete primary structure, expression domains in adult and developing tissues, and comparison to the structures and expression domains of the other types V and XI procollagen chains.

Q9W6T7	PSN1_DANRE	Presenilin-1	10521267	Zebrafish (Danio rerio) presenilin promotes aberrant amyloid beta- peptide production and requires a critical aspartate residue for its function in amyloidogenesis.

P78504	JAG1_HUMAN	Protein jagged-1	9268641	Identification and cloning of the human homolog (JAG1) of the rat Jagged1 gene from the Alagille syndrome critical region at 20p12.

O75594	PGRP1_HUMAN	Peptidoglycan recognition protein 1	9707603	A peptidoglycan recognition protein in innate immunity conserved from insects to humans.

Q6ZY51	PWD_ARATH	Phosphoglucan, water dikinase, chloroplastic	15618411	Identification of a novel enzyme required for starch metabolism in Arabidopsis leaves. The phosphoglucan, water dikinase.

Q7T2X6	BMP3B_XENLA	Bone morphogenetic protein 3B	12885561	Coordination of BMP-3b and cerberus is required for head formation of Xenopus embryos.

Q5RHI5	DTL_DANRE	Denticleless protein homolog	17085480	DTL/CDT2 is essential for both CDT1 regulation and the early G2/M checkpoint.

Q9Y3D6	FIS1_HUMAN	Mitochondrial fission 1 protein	14996942	Levels of human Fis1 at the mitochondrial outer membrane regulate mitochondrial morphology.

P39286	RSGA_ECOLI	Putative ribosome biogenesis GTPase RsgA	18223068	Genetic interaction screens with ordered overexpression and deletion clone sets implicate the Escherichia coli GTPase YjeQ in late ribosome biogenesis.

P61421	VA0D1_HUMAN	V-type proton ATPase subunit d 1	11118322	Structure of the VPATPD gene encoding subunit D of the human vacuolar proton ATPase.

P48003	H2AZ_SCHPO	Histone H2A.Z	7808414	Analysis of a histone H2A variant from fission yeast: evidence for a role in chromosome stability.

Q9Y6N7	ROBO1_HUMAN	Roundabout homolog 1	17848514	Structural insights into the Slit-Robo complex.

P10507	MPPB_YEAST	Mitochondrial-processing peptidase subunit beta	2007593	The MAS-encoded processing protease of yeast mitochondria. Interaction of the purified enzyme with signal peptides and a purified precursor protein.

P12685	TRK1_YEAST	High-affinity potassium transport protein	3043197	TRK1 encodes a plasma membrane protein required for high-affinity potassium transport in Saccharomyces cerevisiae.

Q12358	JLP1_YEAST	Alpha-ketoglutarate-dependent sulfonate dioxygenase	10482536	Cloning and characterization of a sulfonate/alpha-ketoglutarate dioxygenase from Saccharomyces cerevisiae.

P53933	APP1_YEAST	Actin patch protein 1	14737190	Protein interaction networks by proteome peptide scanning.

Q9STE8	TC753_ARATH	Protein TOC75-3, chloroplastic	12766230	Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.

P14773	HMDH_DROME	3-hydroxy-3-methylglutaryl-coenzyme A reductase	9853754	HMG-CoA reductase guides migrating primordial germ cells.

Q8N695	SC5A8_HUMAN	Sodium-coupled monocarboxylate transporter 1	12107270	Identification and characterization of a putative human iodide transporter located at the apical membrane of thyrocytes.

Q96EE3	SEH1_HUMAN	Nucleoporin SEH1	17360435	Cell-cycle-dependent phosphorylation of the nuclear pore Nup107-160 subcomplex.

Q84MA2	IP5P1_ARATH	Type I inositol-1,4,5-trisphosphate 5-phosphatase 1	11402208	Molecular characterization of At5PTase1, an inositol phosphatase capable of terminating inositol trisphosphate signaling.

Q07949	PSR2_YEAST	Probable phosphatase PSR2	10777497	Psr1p/Psr2p, two plasma membrane phosphatases with an essential DXDX(T/V) motif required for sodium stress response in yeast.

Q6NUP7	PP4R4_HUMAN	Serine/threonine-protein phosphatase 4 regulatory subunit 4	18715871	PP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4.

B5LUQ5	FALX4_LITFA	Preprofallaxidin-4	18803332	The fallaxidin peptides from the skin secretion of the eastern dwarf tree frog Litoria fallax. Sequence determination by positive and negative ion electrospray mass spectrometry: antimicrobial activity and cDNA cloning of the fallaxidins.

Q12967	GNDS_HUMAN	Ral guanine nucleotide dissociation stimulator	9365783	Cloning and evaluation of RALGDS as a candidate for the tuberous sclerosis gene TSC1.

P27274	CD59_RAT	CD59 glycoprotein	7528012	Molecular cloning of the rat analogue of human CD59: structural comparison with human CD59 and identification of a putative active site.

Q8IPU5	GR77A_DROME	Putative gustatory receptor 77a	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

P87159	NIF1_SCHPO	Mitosis inhibitor nif1	9135149	Nif1, a novel mitotic inhibitor in Schizosaccharomyces pombe.

P31749	AKT1_HUMAN	RAC-alpha serine/threonine-protein kinase	11994271	A method to identify serine kinase substrates. Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain.

Q8T0W8	DIAP_GASAT	Diapause-specific peptide	14706547	Insect diapause-specific peptide from the leaf beetle has consensus with a putative iridovirus peptide.

Q70KY3	LAC1_MELAO	Laccase-1	12118243	Crystal structure of a laccase from Melanocarpus albomyces with an intact trinuclear copper site.

Q84P21	4CLL5_ARATH	4-coumarate--CoA ligase-like 5	16963437	Identification of a peroxisomal acyl-activating enzyme involved in the biosynthesis of jasmonic acid in Arabidopsis.

P04908	H2A1B_HUMAN	Histone H2A type 1-B/E	6647026	The primary structure and expression of four cloned human histone genes.

Q92328	MDM12_YEAST	Mitochondrial distribution and morphology protein 12	19556461	An ER-mitochondria tethering complex revealed by a synthetic biology screen.

Q9HAW4	CLSPN_HUMAN	Claspin	15707391	DNA-dependent phosphorylation of Chk1 and claspin in a human cell- free system.

P40059	DOT6_YEAST	Transcriptional regulatory protein DOT6	19040720	Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment.

P84743	PBLST_EUGGR	Photoactivated adenylate cyclase subunit beta-like protein ST-	16121285	Photoactivated adenylyl cyclase (PAC) genes in the flagellate Euglena gracilis mutant strains.

Q16787	LAMA3_HUMAN	Laminin subunit alpha-3	8586427	Cloning of the laminin alpha 3 chain gene (LAMA3) and identification of a homozygous deletion in a patient with Herlitz junctional epidermolysis bullosa.

Q9VD73	GLEC_DROME	Gliolectin	8631270	Gliolectin is a novel carbohydrate-binding protein expressed by a subset of glia in the embryonic Drosophila nervous system.

Q13093	PAFA_HUMAN	Platelet-activating factor acetylhydrolase	8675689	Platelet-activating factor acetylhydrolase deficiency. A missense mutation near the active site of an anti-inflammatory phospholipase.

Q9US33	SAT_SCHPO	Putative serine acetyltransferase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O95990	F107A_HUMAN	Protein FAM107A	10564580	Loss of expression of the DRR1 gene at chromosomal segment 3p21.1 in renal cell carcinoma.

Q92207	HOG1_CANAL	Mitogen-activated protein kinase HOG1	12684384	The Hog1 mitogen-activated protein kinase is essential in the oxidative stress response and chlamydospore formation in Candida albicans.

Q9D2G5	SYNJ2_MOUSE	Synaptojanin-2	9442075	Developmentally regulated alternative splicing in a novel synaptojanin.

P40026	KRE29_YEAST	DNA repair protein KRE29	14562095	Global analysis of protein localization in budding yeast.

Q8UVJ6	VANG2_DANRE	Vang-like protein 2	9007236	Mutations affecting morphogenesis during gastrulation and tail formation in the zebrafish, Danio rerio.

P39428	TRAF1_MOUSE	TNF receptor-associated factor 1	18849341	FLN29 deficiency reveals its negative regulatory role in the Toll- like receptor (TLR) and retinoic acid-inducible gene I (RIG-I)-like helicase signaling pathway.

Q04665	GPA2_SCHPO	Guanine nucleotide-binding protein alpha-2 subunit	1340462	Characterization of a fission yeast gene, gpa2, that encodes a G alpha subunit involved in the monitoring of nutrition.

Q9Y3R0	GRIP1_HUMAN	Glutamate receptor-interacting protein 1	10197531	EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains.

P23248	RS3A2_YEAST	40S ribosomal protein S1-B	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q8VBV4	FBXW7_MOUSE	F-box/WD repeat-containing protein 7	11735228	Characterization of a mouse gene (Fbxw6) that encodes a homologue of Caenorhabditis elegans SEL-10.

P15529	MCP_HUMAN	Membrane cofactor protein	1711570	Membrane cofactor protein of the complement system: alternative splicing of serine/threonine/proline-rich exons and cytoplasmic tails produces multiple isoforms that correlate with protein phenotype.

P53390	MEP3_YEAST	Ammonium transporter MEP3	11486013	Evidence that fungal MEP proteins mediate diffusion of the uncharged species NH(3) across the cytoplasmic membrane.

O74557	NCB5R_SCHPO	NADH-cytochrome b5 reductase 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q84WP6	NAC43_ARATH	NAC domain-containing protein 43	17237351	NAC transcription factors, NST1 and NST3, are key regulators of the formation of secondary walls in woody tissues of Arabidopsis.

Q04372	TAP42_YEAST	Type 2A phosphatase-associated protein 42	8756348	Nutrients, via the Tor proteins, stimulate the association of Tap42 with type 2A phosphatases.

O74630	ATM_SCHPO	Serine/threonine-protein kinase tel1	10430579	Genetic control of telomere integrity in Schizosaccharomyces pombe: rad3(+) and tel1(+) are parts of two regulatory networks independent of the downstream protein kinases chk1(+) and cds1(+).

Q95YL4	PEFB_DICDI	Penta-EF hand domain-containing protein 2	11927596	Biochemical characterization of two analogues of the apoptosis-linked gene 2 protein in Dictyostelium discoideum and interaction with a physiological partner in mammals, murine Alix.

Q02535	ID3_HUMAN	DNA-binding protein inhibitor ID-3	8437843	An immediate early human gene encodes an Id-like helix-loop-helix protein and is regulated by protein kinase C activation in diverse cell types.

Q9BUN8	DERL1_HUMAN	Derlin-1	15215855	A membrane protein required for dislocation of misfolded proteins from the ER.

Q9WVI9	JIP1_MOUSE	C-Jun-amino-terminal kinase-interacting protein 1	11238452	Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules.

Q9FHM4	MA653_ARATH	65-kDa microtubule-associated protein 3	19060108	The C-terminal variable region specifies the dynamic properties of Arabidopsis microtubule-associated protein MAP65 isotypes.

P19020	DRD3_RAT	D(3) dopamine receptor	1975644	Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics.

P30664	MCM4B_XENLA	DNA replication licensing factor mcm4-B	9512418	Developmental regulation of MCM replication factors in Xenopus laevis.

Q9Y7X6	ISH1_SCHPO	Stress response protein ish1	11751918	The fission yeast ES2 homologue, Bis1, interacts with the Ish1 stress-responsive nuclear envelope protein.

P10127	ADH4_YEAST	Alcohol dehydrogenase 4	14562095	Global analysis of protein localization in budding yeast.

P41546	HAC1_YEAST	Transcriptional activator HAC1	8898193	A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein response.

D0VYS2	HSF3_MOUSE	Heat shock factor protein 3	19864465	A novel mouse HSF3 has the potential to activate nonclassical heat- shock genes during heat shock.

Q91731	SX11A_XENLA	Transcription factor Sox-11-A	9332350	XLS13A and XLS13B: SRY-related genes of Xenopus laevis.

Q9UBI6	GBG12_HUMAN	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12	10819326	Genomic characterization of the human heterotrimeric G protein alpha, beta, and gamma subunit genes.

O74397	ASND1_SCHPO	Asparagine synthetase domain-containing protein C4F6.11c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O59737	GYP1_SCHPO	GTPase-activating protein gyp1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UL15	BAG5_HUMAN	BAG family molecular chaperone regulator 5	9873016	An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators.

Q9EP66	G109A_MOUSE	G-protein coupled receptor 109A	12646212	Molecular identification of nicotinic acid receptor.

P29350	PTN6_HUMAN	Tyrosine-protein phosphatase non-receptor type 6	1732748	Protein tyrosine phosphatase containing SH2 domains: characterization, preferential expression in hematopoietic cells, and localization to human chromosome 12p12-p13.

Q93ZM9	TIF9_ARATH	Protein TIFY 9	20360743	NINJA connects the co-repressor TOPLESS to jasmonate signalling.

Q7TNI4	I22R2_RAT	Interleukin-22 receptor subunit alpha-2	15201862	Cloning of murine IL-22 receptor alpha 2 and comparison with its human counterpart.

Q9NYG8	KCNK4_HUMAN	Potassium channel subfamily K member 4	10767409	Cloning and expression of human TRAAK, a polyunsaturated fatty acids- activated and mechano-sensitive K(+) channel.

P33078	IAA5_ARATH	Auxin-responsive protein IAA5	12036262	Genetics of Aux/IAA and ARF action in plant growth and development.

Q63604	NTRK2_RAT	BDNF/NT-3 growth factors receptor	15167895	A unique pathway for sustained neurotrophin signaling through an ankyrin-rich membrane-spanning protein.

Q9FPN7	AGL31_ARATH	Agamous-like MADS-box protein AGL31	11115127	MADS-box gene evolution beyond flowers: expression in pollen, endosperm, guard cells, roots and trichomes.

P33077	IAA4_ARATH	Auxin-responsive protein IAA4	7658471	The PS-IAA4/5-like family of early auxin-inducible mRNAs in Arabidopsis thaliana.

P08621	RU17_HUMAN	U1 small nuclear ribonucleoprotein 70 kDa	14561889	Association of polyadenylation cleavage factor I with U1 snRNP.

P38816	TRXB2_YEAST	Thioredoxin reductase 2, mitochondrial	10037727	Identification and functional characterization of a novel mitochondrial thioredoxin system in Saccharomyces cerevisiae.

P54475	CSHB_BACSU	DEAD-box ATP-dependent RNA helicase cshB	16352840	Cold-induced putative DEAD box RNA helicases CshA and CshB are essential for cold adaptation and interact with cold shock protein B in Bacillus subtilis.

Q6X1Y6	ACCN3_MOUSE	Amiloride-sensitive cation channel 3	11754838	The DRASIC cation channel contributes to the detection of cutaneous touch and acid stimuli in mice.

Q16637	SMN_HUMAN	Survival motor neuron protein	9845364	A novel function for SMN, the spinal muscular atrophy disease gene product, in pre-mRNA splicing.

P24046	GBRR1_HUMAN	Gamma-aminobutyric acid receptor subunit rho-1	1849271	Cloning of the gamma-aminobutyric acid (GABA) rho 1 cDNA: a GABA receptor subunit highly expressed in the retina.

Q92794	MYST3_HUMAN	Histone acetyltransferase MYST3	16387653	ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.

Q8T3Y0	SINAL_DROME	Probable E3 ubiquitin-protein ligase sinah	17962185	Two modes of degradation of the tramtrack transcription factors by Siah homologues.

O13852	POZ1_SCHPO	Protection of telomeres protein poz1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P97557	KCNV1_RAT	Potassium voltage-gated channel subfamily V member 1	9169526	Identification and functional characterization of a K+ channel alpha- subunit with regulatory properties specific to brain.

P19158	IRA2_YEAST	Inhibitory regulator protein IRA2	14562095	Global analysis of protein localization in budding yeast.

P35222	CTNB1_HUMAN	Catenin beta-1	16858403	The inner nuclear membrane protein emerin regulates beta-catenin activity by restricting its accumulation in the nucleus.

P49748	ACADV_HUMAN	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	7668252	Cloning of human very-long-chain acyl-coenzyme A dehydrogenase and molecular characterization of its deficiency in two patients.

Q8VIC9	V1R43_MOUSE	Vomeronasal type-1 receptor 43	11116090	Sequence diversity and genomic organization of vomeronasal receptor genes in the mouse.

Q9FH02	FTSH5_ARATH	ATP-dependent zinc metalloprotease FTSH 5, chloroplastic	12167156	The VAR1 locus of Arabidopsis encodes a chloroplastic FtsH and is responsible for leaf variegation in the mutant alleles.

P18117	THBA_XENLA	Thyroid hormone receptor beta-A	2402492	Xenopus laevis alpha and beta thyroid hormone receptors.

Q9FKT0	ARP8_ARATH	Actin-related protein 8	11891255	Arabidopsis contains ancient classes of differentially expressed actin-related protein genes.

Q55DA0	ABCGM_DICDI	ABC transporter G family member 22	18164290	Screening of genes involved in cell migration in Dictyostelium.

P31150	GDIA_HUMAN	Rab GDP dissociation inhibitor alpha	7543319	Expression patterns of two human genes coding for different rab GDP- dissociation inhibitors (GDIs), extremely conserved proteins involved in cellular transport.

Q9USX9	ELOC_SCHPO	Elongin-C	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q15648	MED1_HUMAN	Mediator of RNA polymerase II transcription subunit 1	7776974	Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor.

Q12905	ILF2_HUMAN	Interleukin enhancer-binding factor 2	10574923	Autoantibodies define a family of proteins with conserved double- stranded RNA-binding domains as well as DNA binding activity.

Q9UKG1	DP13A_HUMAN	DCC-interacting protein 13-alpha	15016378	APPL proteins link Rab5 to nuclear signal transduction via an endosomal compartment.

B7ZSG3	WT1A_XENLA	Wilms tumor protein homolog A	8725280	Wilms' tumor suppressor gene is involved in the development of disparate kidney forms: evidence from expression in the Xenopus pronephros.

Q16819	MEP1A_HUMAN	Meprin A subunit alpha	8262185	Cloning of the PABA peptide hydrolase alpha subunit (PPH alpha) from human small intestine and its expression in COS-1 cells.

P62331	ARF6_MOUSE	ADP-ribosylation factor 6	8947846	Structure and intracellular localization of mouse ADP-ribosylation factors type 1 to type 6 (ARF1-ARF6).

P20061	TCO1_HUMAN	Transcobalamin-1	2777761	Structure of the cDNA encoding transcobalamin I, a neutrophil granule protein.

Q9QXZ6	SO1A1_MOUSE	Solute carrier organic anion transporter family member 1A1	10600646	Molecular cloning and functional characterization of the mouse organic anion transporting polypeptide 1 (Oatp1) and mapping of the gene to chromosome X.

Q23023	UNC51_CAEEL	Serine/threonine-protein kinase unc-51	15539493	The conserved kinase UNC-51 acts with VAB-8 and UNC-14 to regulate axon outgrowth in C. elegans.

Q98TW1	NCOA2_DANRE	Nuclear receptor coactivator 2	18295965	A role for the transcription intermediary factor 2 in zebrafish myelopoiesis.

Q09699	SNF5_SCHPO	SWI/SNF chromatin-remodeling complex subunit snf5	18622392	Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast.

Q86VW1	S22AG_HUMAN	Solute carrier family 22 member 16	15963465	Characterization of the organic cation transporter SLC22A16: a doxorubicin importer.

Q9USV4	MEP33_SCHPO	mRNA export protein 33	15116432	Identification of genes encoding putative nucleoporins and transport factors in the fission yeast Schizosaccharomyces pombe: a deletion analysis.

P22812	TUBE_DROME	Protein Tube	10589682	Three-dimensional structure of a complex between the death domains of Pelle and Tube.

Q3ZMH1	SC5A8_DANRE	Sodium-coupled monocarboxylate transporter 1	17255103	Zebrafish Slc5a12 encodes an electroneutral sodium monocarboxylate transporter (SMCTn). A comparison with the electrogenic SMCT (SMCTe/Slc5a8).

P53718	NRM1_YEAST	Transcription factor NRM1	14562095	Global analysis of protein localization in budding yeast.

O74454	STS5_SCHPO	Protein sts5	8886983	The fission yeast sts5+ gene is required for maintenance of growth polarity and functionally interacts with protein kinase C and an osmosensing MAP-kinase pathway.

Q9BT40	INP5K_HUMAN	Inositol polyphosphate 5-phosphatase K	10753883	Identification and characterization of a novel inositol polyphosphate 5-phosphatase.

P27170	PON1_RABIT	Serum paraoxonase/arylesterase 1	11266077	Rabbits possess a serum paraoxonase polymorphism similar to the human Q192R.

Q38814	THI4_ARATH	Thiazole biosynthetic enzyme, chloroplastic	8790291	Thi1, a thiamine biosynthetic gene in Arabidopsis thaliana, complements bacterial defects in DNA repair.

P48994	TRPL_DROME	Transient-receptor-potential-like protein	10896160	TRPgamma, a Drosophila TRP-related subunit, forms a regulated cation channel with TRPL.

P38319	TYDP1_YEAST	Tyrosyl-DNA phosphodiesterase 1	10521354	Yeast gene for a Tyr-DNA phosphodiesterase that repairs topoisomerase I complexes.

P84910	CYT2_CAPHI	Cystatin-2	16257555	Isolation, characterization and kinetics of goat cystatins.

Q15075	EEA1_HUMAN	Early endosome antigen 1	10491193	Direct interaction of EEA1 with Rab5b.

O08547	SC22B_MOUSE	Vesicle-trafficking protein SEC22b	9094723	Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells.

P30416	FKBP4_MOUSE	Peptidyl-prolyl cis-trans isomerase FKBP4	7693550	Cloning and expression of a mouse cDNA encoding p59, an immunophilin that associates with the glucocorticoid receptor.

O62618	MK14A_DROME	Mitogen-activated protein kinase 14A	9417090	Molecular cloning and characterization of a Drosophila p38 mitogen- activated protein kinase.

Q6Q473	CLCA4_MOUSE	Calcium-activated chloride channel regulator 4	15284223	Molecular and functional analyses of two new calcium-activated chloride channel family members from mouse eye and intestine.

P70178	SIX5_MOUSE	Homeobox protein SIX5	10490620	Cooperation of six and eya in activation of their target genes through nuclear translocation of Eya.

O08722	UNC5B_RAT	Netrin receptor UNC5B	9126742	Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors.

Q07528	ATG20_YEAST	Autophagy-related protein 20	12554655	Retromer and the sorting nexins Snx4/41/42 mediate distinct retrieval pathways from yeast endosomes.

P81921	OR47A_DROME	Odorant receptor 47a	10069338	A novel family of divergent seven-transmembrane proteins: candidate odorant receptors in Drosophila.

Q9S7A9	SPL4_ARATH	Squamosa promoter-binding-like protein 4	16914499	Temporal regulation of shoot development in Arabidopsis thaliana by miR156 and its target SPL3.

Q16698	DECR_HUMAN	2,4-dienoyl-CoA reductase, mitochondrial	15531764	Structure and reactivity of human mitochondrial 2,4-dienoyl-CoA reductase: enzyme-ligand interactions in a distinctive short-chain reductase active site.

Q15063	POSTN_HUMAN	Periostin	12235007	Periostin secreted by epithelial ovarian carcinoma is a ligand for alpha(V)beta(3) and alpha(V)beta(5) integrins and promotes cell motility.

P17174	AATC_HUMAN	Aspartate aminotransferase, cytoplasmic	2241899	The amino acid sequence of cytosolic aspartate aminotransferase from human liver.

Q9QZL0	RIPK3_MOUSE	Receptor-interacting serine/threonine-protein kinase 3	10490590	Mouse receptor interacting protein 3 does not contain a caspase- recruiting or a death domain but induces apoptosis and activates NF- kappaB.

Q9NYK5	RM39_HUMAN	39S ribosomal protein L39, mitochondrial	11167009	Heart-specific splice-variant of a human mitochondrial ribosomal protein (mRNA processing; tissue specific splicing).

O74340	DCA13_SCHPO	Protein sof1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P83258	TXDP3_PIRLC	Delta-amaurobitoxin-Pl1c	10971590	Isolation, synthesis and pharmacological characterization of delta- palutoxins IT, novel insecticidal toxins from the spider Paracoelotes luctuosus (Amaurobiidae).

Q94KI8	TPC1_ARATH	Two pore calcium channel protein 1	14760709	Large-scale characterization of integral proteins from Arabidopsis vacuolar membrane by two-dimensional liquid chromatography.

O96622	ARPC1_DICDI	Actin-related protein 2/3 complex subunit 1	17296313	Vectors for expression of proteins with single or combinatorial fluorescent protein and tandem affinity purification tags in Dictyostelium.

P84104	SRSF3_MOUSE	Serine/arginine-rich splicing factor 3	2030943	A differentially expressed murine RNA encoding a protein with similarities to two types of nucleic acid binding motifs.

Q9ET64	NSMA_RAT	Sphingomyelin phosphodiesterase 2	10832103	Cloning and expression of rat neutral sphingomyelinase: enzymological characterization and identification of essential histidine residues.

O42845	YFH7_SCHPO	Uncharacterized RING finger protein C23A1.07	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q93646	SNT1_CAEEL	Syntrophin-1	10561496	In vitro interactions of Caenorhabditis elegans dystrophin with dystrobrevin and syntrophin.

Q3UR85	MRF_MOUSE	Myelin gene regulatory factor	19596243	Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelination.

P17555	CAP_YEAST	Adenylyl cyclase-associated protein	8552082	A conserved proline-rich region of the Saccharomyces cerevisiae cyclase-associated protein binds SH3 domains and modulates cytoskeletal localization.

P36506	MP2K2_RAT	Dual specificity mitogen-activated protein kinase kinase 2	8393135	Identification and characterization of a new mammalian mitogen- activated protein kinase kinase, MKK2.

Q9UBN7	HDAC6_HUMAN	Histone deacetylase 6	19033385	The ubiquitin-like modifier FAT10 interacts with HDAC6 and localizes to aggresomes under proteasome inhibition.

O94274	YORQ_SCHPO	Uncharacterized protein P8B7.26	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P84813	POTM1_SOLTU	Potamin-1	15809084	Antimicrobial activity studies on a trypsin-chymotrypsin protease inhibitor obtained from potato.

Q9XTF3	MBK2_CAEEL	Dual specificity tyrosine-phosphorylation-regulated kinase mbk-2	16338136	The C. elegans DYRK Kinase MBK-2 marks oocyte proteins for degradation in response to meiotic maturation.

Q96JK9	MAML3_HUMAN	Mastermind-like protein 3	12370315	Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors.

Q9VUX2	MIB_DROME	E3 ubiquitin-protein ligase mind-bomb	15760269	Two distinct E3 ubiquitin ligases have complementary functions in the regulation of delta and serrate signaling in Drosophila.

P21108	PRPS3_HUMAN	Ribose-phosphate pyrophosphokinase 3	2168892	A human testis-specific mRNA for phosphoribosylpyrophosphate synthetase that initiates from a non-AUG codon.

Q9HFF5	PDS5_SCHPO	Sister chromatid cohesion protein pds5	11598020	Establishment and maintenance of sister chromatid cohesion in fission yeast by a unique mechanism.

P22134	MAG_YEAST	DNA-3-methyladenine glycosylase	2265620	Saccharomyces cerevisiae 3-methyladenine DNA glycosylase has homology to the AlkA glycosylase of E. coli and is induced in response to DNA alkylation damage.

O08689	GDF8_MOUSE	Growth/differentiation factor 8	12595574	Regulation of myostatin in vivo by growth and differentiation factor- associated serum protein-1: a novel protein with protease inhibitor and follistatin domains.

O75410	TACC1_HUMAN	Transforming acidic coiled-coil-containing protein 1	14603251	TACC1-chTOG-Aurora A protein complex in breast cancer.

P30304	MPIP1_HUMAN	M-phase inducer phosphatase 1	11139144	Alternative splicing in the regulatory region of the human phosphatases CDC25A and CDC25C.

P53898	NSG2_YEAST	Protein NSG2	14562095	Global analysis of protein localization in budding yeast.

Q9VBW9	DANR_DROME	Protein distal antenna-related	12571108	Distal antenna and distal antenna related encode nuclear proteins containing pipsqueak motifs involved in antenna development in Drosophila.

Q9UQ10	DHDH_HUMAN	Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase	10477285	Cloning and sequencing of the cDNA species for mammalian dimeric dihydrodiol dehydrogenases.

Q9JLQ0	CD2AP_MOUSE	CD2-associated protein	10913159	In vivo interaction of the adapter protein CD2-associated protein with the type 2 polycystic kidney disease protein, polycystin-2.

P40496	RT25_YEAST	37S ribosomal protein S25, mitochondrial	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Q8VYZ0	ORTH2_ARATH	E3 ubiquitin-protein ligase ORTHRUS 2	18704160	Three SRA-domain methylcytosine-binding proteins cooperate to maintain global CpG methylation and epigenetic silencing in Arabidopsis.

O02194	PSN_DROME	Presenilin homolog	10662508	Posttranslational modification and plasma membrane localization of the Drosophila melanogaster presenilin.

Q9V464	ASF1_DROME	Histone chaperone asf1	12381660	Histone chaperone ASF1 cooperates with the Brahma chromatin- remodelling machinery.

P28040	DPOA_SCHPO	DNA polymerase alpha catalytic subunit	14766746	Primer utilization by DNA polymerase alpha-primase is influenced by its interaction with Mcm10p.

Q08380	LG3BP_HUMAN	Galectin-3-binding protein	8390986	Cloning and characterization of a human Mac-2-binding protein, a new member of the superfamily defined by the macrophage scavenger receptor cysteine-rich domain.

Q95V55	FOXO_DROME	Forkhead box protein O	15175753	Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body.

Q8VBS7	V1R42_MOUSE	Vomeronasal type-1 receptor 42	11116090	Sequence diversity and genomic organization of vomeronasal receptor genes in the mouse.

O14628	ZN195_HUMAN	Zinc finger protein 195	9344677	Characterization of a KRAB family zinc finger gene, ZNF195, mapping to chromosome band 11p15.5.

P32335	MSS51_YEAST	Protein MSS51, mitochondrial	15306853	Mss51p and Cox14p jointly regulate mitochondrial Cox1p expression in Saccharomyces cerevisiae.

Q01196	RUNX1_HUMAN	Runt-related transcription factor 1	11965546	MOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2.

O70249	OGG1_RAT	N-glycosylase/DNA lyase	9801319	Rat 7,8-dihydro-8-oxoguanine DNA glycosylase: substrate specificity, kinetics and cleavagemechanism at an apurinic site.

Q08548	ALE1_YEAST	Lysophospholipid acyltransferase	17726007	Identification of a novel lysophospholipid acyltransferase in Saccharomyces cerevisiae.

P32792	YHH7_YEAST	UPF0744 protein YSC83	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P83141	AFP1L_MALPA	Antifungal protein 1 large subunit	11118343	Potent heterologous antifungal proteins from cheeseweed (Malva parviflora).

Q9Y230	RUVB2_HUMAN	RuvB-like 2	10524211	Isolation, molecular characterization, and tissue-specific expression of ECP-51 and ECP-54 (TIP49), two homologous, interacting erythroid cytosolic proteins.

P06844	SPT3_YEAST	Protein SPT3	12370284	Differential requirement of SAGA components for recruitment of TATA- box-binding protein to promoters in vivo.

P39904	VPS52_YEAST	Vacuolar protein sorting-associated protein 52	11689439	An effector of Ypt6p binds the SNARE Tlg1p and mediates selective fusion of vesicles with late Golgi membranes.

Q39065	COPT1_ARATH	Copper transporter 1	7499355	Molecular characterization of a putative Arabidopsis thaliana copper transporter and its yeast homologue.

Q15843	NEDD8_HUMAN	NEDD8	9353319	Characterization of NEDD8, a developmentally down-regulated ubiquitin-like protein.

Q04005	LIC4_YEAST	Protein ATC1/LIC4	10102375	Lic4, a nuclear phosphoprotein that cooperates with calcineurin to regulate cation homeostasis in Saccharomyces cerevisiae.

Q03060	CREM_HUMAN	cAMP-responsive element modulator	7916662	Human CREM gene: evolutionary conservation, chromosomal localization, and inducibility of the transcript.

Q18964	WDFY2_CAEEL	WD repeat and FYVE domain-containing protein 2	16873553	The WD40 and FYVE domain containing protein 2 defines a class of early endosomes necessary for endocytosis.

Q08581	SLK19_YEAST	Kinetochore protein SLK19	10427094	Slk19p is a centromere protein that functions to stabilize mitotic spindles.

Q12160	YP063_YEAST	Uncharacterized protein YPR063C	14562095	Global analysis of protein localization in budding yeast.

O35932	PD2RL_RAT	Prostaglandin D2 receptor-like	9721719	Dominant expression of rat prostanoid DP receptor mRNA in leptomeninges, inner segments of photoreceptor cells, iris epithelium, and ciliary processes.

P26368	U2AF2_HUMAN	Splicing factor U2AF 65 kDa subunit	19574390	Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing.

P23594	PP2A1_YEAST	Serine/threonine-protein phosphatase PP2A-1 catalytic subunit	2176150	Saccharomyces cerevisiae protein phosphatase 2A performs an essential cellular function and is encoded by two genes.

Q9FV49	AMP2A_ARATH	Methionine aminopeptidase 2A	11060042	Identification of eukaryotic peptide deformylases reveals universality of N-terminal protein processing mechanisms.

P97425	ECP2_MOUSE	Eosinophil cationic protein 2	12855582	Eosinophil-derived neurotoxin (EDN), an antimicrobial protein with chemotactic activities for dendritic cells.

P49731	MCM6_SCHPO	DNA replication licensing factor mcm6	7865880	Fission yeast minichromosome loss mutants mis cause lethal aneuploidy and replication abnormality.

O75844	FACE1_HUMAN	CAAX prenyl protease 1 homolog	10373325	Identification and chromosomal location of two human genes encoding enzymes potentially involved in proteolytic maturation of farnesylated proteins.

O60141	CWC16_SCHPO	Protein cwc16	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P70279	SURF6_MOUSE	Surfeit locus protein 6	9548374	The SURF-6 protein is a component of the nucleolar matrix and has a high binding capacity for nucleic acids in vitro.

Q9UU89	HAM1_SCHPO	Protein ham1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P39947	CCNC_RAT	Cyclin-C	8336937	Cyclin G: a new mammalian cyclin with homology to fission yeast Cig1.

P38888	MNL1_YEAST	ER degradation-enhancing alpha-mannosidase-like protein 1	11254655	Mnl1p, an alpha -mannosidase-like protein in yeast Saccharomyces cerevisiae, is required for endoplasmic reticulum-associated degradation of glycoproteins.

Q01826	SATB1_HUMAN	DNA-binding protein SATB1	15851481	Nuclear matrix binding regulates SATB1-mediated transcriptional repression.

O70127	ABCBB_RAT	Bile salt export pump	15159385	Identification of HAX-1 as a protein that binds bile salt export protein and regulates its abundance in the apical membrane of Madin- Darby canine kidney cells.

P10860	DHE3_RAT	Glutamate dehydrogenase 1, mitochondrial	1684101	Identification of the CoA-modified forms of mitochondrial acetyl-CoA acetyltransferase and of glutamate dehydrogenase as nearest-neighbour proteins.

Q9P6P5	BET3_SCHPO	Transport protein particle subunit bet3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q01292	ILV5_SPIOL	Ketol-acid reductoisomerase, chloroplastic	9218783	The crystal structure of plant acetohydroxy acid isomeroreductase complexed with NADPH, two magnesium ions and a herbicidal transition state analog determined at 1.65-A resolution.

Q9UPA5	BSN_HUMAN	Protein bassoon	10329005	The presynaptic cytomatrix protein Bassoon: sequence and chromosomal localization of the human BSN gene.

Q7G9P4	ALDO3_ARATH	Abscisic-aldehyde oxidase	10972874	Abscisic aldehyde oxidase in leaves of Arabidopsis thaliana.

P40383	XRN1_SCHPO	5'-3' exoribonuclease 1	8188690	A multifunctional exonuclease from vegetative Schizosaccharomyces pombe cells exhibiting in vitro strand exchange activity.

Q9GZV5	WWTR1_HUMAN	WW domain-containing transcription regulator protein 1	19324877	TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition.

Q76CY5	DAZL_XENTR	Deleted in azoospermia-like	14745962	Tracing of Xenopus tropicalis germ plasm and presumptive primordial germ cells with the Xenopus tropicalis DAZ-like gene.

O95835	LATS1_HUMAN	Serine/threonine-protein kinase LATS1	9988268	Human homologue of the Drosophila melanogaster lats tumour suppressor modulates CDC2 activity.

P34810	CD68_HUMAN	Macrosialin	7680921	Molecular cloning of CD68, a human macrophage marker related to lysosomal glycoproteins.

P06986	HIS8_ECOLI	Histidinol-phosphate aminotransferase	2999081	Cloning, structure, and expression of the Escherichia coli K-12 hisC gene.

Q92664	TF3A_HUMAN	Transcription factor IIIA	7789179	Molecular cloning, characterization, and chromosomal mapping of a novel human gene (GTF3A) that is highly homologous to Xenopus transcription factor IIIA.

Q9R216	FZD9_MOUSE	Frizzled-9	10198163	Characterization and expression pattern of the frizzled gene Fzd9, the mouse homolog of FZD9 which is deleted in Williams-Beuren syndrome.

Q9VTY6	UBE2C_DROME	Ubiquitin-conjugating enzyme E2 C	15458643	The E2-C vihar is required for the correct spatiotemporal proteolysis of cyclin B and itself undergoes cyclical degradation.

O35082	KLOT_MOUSE	Klotho	17086194	Klotho converts canonical FGF receptor into a specific receptor for FGF23.

P32828	SLX5_YEAST	E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5	16325482	Suppression of genomic instability by SLX5 and SLX8 in Saccharomyces cerevisiae.

O75711	SCRG1_HUMAN	Scrapie-responsive protein 1	9660755	Characterization of the human analogue of a scrapie-responsive gene.

P49238	CX3C1_HUMAN	CX3C chemokine receptor 1	9390561	Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion.

P11940	PABP1_HUMAN	Polyadenylate-binding protein 1	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

Q23985	DTX_DROME	Protein deltex	8150285	A member of the Notch group of interacting loci, deltex encodes a cytoplasmic basic protein.

Q12340	YRM1_YEAST	Zinc finger transcription factor YRM1	14562095	Global analysis of protein localization in budding yeast.

Q12341	HAT1_YEAST	Histone acetyltransferase type B catalytic subunit	10982821	Type B histone acetyltransferase Hat1p participates in telomeric silencing.

Q9HPR6	HMAT_HALSA	Heme-based aerotactic transducer hemAT	10676961	Myoglobin-like aerotaxis transducers in Archaea and Bacteria.

P60932	UPPP_ECOLI	Undecaprenyl-diphosphatase	15138271	The bacA gene of Escherichia coli encodes an undecaprenyl pyrophosphate phosphatase activity.

P62847	RS24_HUMAN	40S ribosomal protein S24	18230666	Mutation of ribosomal protein RPS24 in Diamond-Blackfan anemia results in a ribosome biogenesis disorder.

Q920D2	DYR_RAT	Dihydrofolate reductase	11502523	Isolation of rat dihydrofolate reductase gene and characterization of recombinant enzyme.

Q8VYN6	K6PF5_ARATH	6-phosphofructokinase 5, chloroplastic	17485088	Characterisation of the ATP-dependent phosphofructokinase gene family from Arabidopsis thaliana.

Q9NV70	EXOC1_HUMAN	Exocyst complex component 1	11406615	The brain exocyst complex interacts with RalA in a GTP-dependent manner: identification of a novel mammalian Sec3 gene and a second Sec15 gene.

O77059	CRY1_DROME	Cryptochrome-1	10417378	Light-dependent sequestration of TIMELESS by CRYPTOCHROME.

B7ZSG3	WT1A_XENLA	Wilms tumor protein homolog A	9758706	Precocious expression of the Wilms' tumor gene xWT1 inhibits embryonic kidney development in Xenopus laevis.

Q93Y94	RPOT1_NICSY	DNA-directed RNA polymerase 1, mitochondrial	11722843	Genomic organization and organ-specific expression of a nuclear gene encoding phage-type RNA polymerase in Nicotiana sylvestris.

Q9FHW7	SKP1B_ARATH	SKP1-like protein 1B	12445118	COI1 links jasmonate signalling and fertility to the SCF ubiquitin- ligase complex in Arabidopsis.

Q04226	TAF11_YEAST	Transcription initiation factor TFIID subunit 11	9083082	Cloning and characterization of an essential Saccharomyces cerevisiae gene, TAF40, which encodes yTAFII40, an RNA polymerase II-specific TATA-binding protein-associated factor.

P53688	HST4_YEAST	NAD-dependent histone deacetylase HST4	7498786	The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability.

O75969	AKAP3_HUMAN	A-kinase anchor protein 3	10319321	Isolation and molecular characterization of AKAP110, a novel, sperm- specific protein kinase A-anchoring protein.

Q90999	TGFR2_CHICK	TGF-beta receptor type-2	12589747	Solution structure of the chick TGFbeta type II receptor ligand- binding domain.

P47116	PTK2_YEAST	Serine/threonine-protein kinase PTK2/STK2	8920934	A second gene encoding a putative serine/threonine protein kinase which enhances spermine uptake in Saccharomyces cerevisiae.

O15172	PSPHL_HUMAN	Putative phosphoserine phosphatase-like protein	9573387	Identification of a novel c-DNA overexpressed in Fanconi's anemia fibroblasts partially homologous to a putative L-3-phosphoserine- phosphatase.

P42325	NCAH_DROME	Neurocalcin homolog	7989365	A highly conserved homologue of bovine neurocalcin in Drosophila melanogaster is a Ca(2+)-binding protein expressed in neuronal tissues.

Q8JGN5	BI51A_XENLA	Baculoviral IAP repeat-containing protein 5.1-A	12464631	Cohesin release is required for sister chromatid resolution, but not for condensin-mediated compaction, at the onset of mitosis.

P36169	SKG1_YEAST	Suppressor of lethality of KEX2 GAS1 double null mutant protein 1	15645486	SKG1, a suppressor gene of synthetic lethality of kex2Deltagas1Delta mutations, encodes a novel membrane protein that affects cell wall composition.

P43058	DUT_CANAL	Deoxyuridine 5'-triphosphate nucleotidohydrolase	7874734	MluI site-dependent transcriptional regulation of the Candida albicans dUTPase gene.

Q8NI27	THOC2_HUMAN	THO complex subunit 2	15998806	Recruitment of the human TREX complex to mRNA during splicing.

Q920M2	RNF39_RAT	RING finger protein 39	11716498	LIRF, a gene induced during hippocampal long-term potentiation as an immediate-early gene, encodes a novel RING finger protein.

Q02883	FMP30_YEAST	N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P39964	CEF1_SCHPO	Pre-mRNA-splicing factor cef1	10409726	Myb-related fission yeast cdc5p is a component of a 40S snRNP- containing complex and is essential for pre-mRNA splicing.

P51965	UB2E1_HUMAN	Ubiquitin-conjugating enzyme E2 E1	20061386	The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.

Q4V7H8	BORE2_XENLA	Borealin-2	15260989	The chromosomal passenger complex is required for chromatin-induced microtubule stabilization and spindle assembly.

P48559	YPT11_YEAST	GTP-binding protein YPT11	12391144	Complex formation with Ypt11p, a rab-type small GTPase, is essential to facilitate the function of Myo2p, a class V myosin, in mitochondrial distribution in Saccharomyces cerevisiae.

Q9NZG7	NINJ2_HUMAN	Ninjurin-2	10627596	Ninjurin2, a novel homophilic adhesion molecule, is expressed in mature sensory and enteric neurons and promotes neurite outgrowth.

P33226	TORC_ECOLI	Cytochrome c-type protein torC	11562502	An unsuspected autoregulatory pathway involving apocytochrome TorC and sensor TorS in Escherichia coli.

Q61171	PRDX2_MOUSE	Peroxiredoxin-2	17141802	Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factors.

Q9Y6D9	MD1L1_HUMAN	Mitotic spindle assembly checkpoint protein MAD1	14978040	NEK2A interacts with MAD1 and possibly functions as a novel integrator of the spindle checkpoint signaling.

Q14195	DPYL3_HUMAN	Dihydropyrimidinase-related protein 3	8973361	A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution.

Q9BJZ5	FUSIL_DROME	RNA-binding protein fusilli	19285943	ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing.

O88484	PDP2_RAT	[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial	9651365	Isoenzymes of pyruvate dehydrogenase phosphatase. DNA-derived amino acid sequences, expression, and regulation.

O14503	BHE40_HUMAN	Class E basic helix-loop-helix protein 40	11278694	Regulation of STRA13 by the von Hippel-Lindau tumor suppressor protein, hypoxia, and the UBC9/ubiquitin proteasome degradation pathway.

Q8I1N6	AP2A_PLAF7	AP2/ERF domain-containing protein PFD0985w	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

Q23921	PKIA_DICDI	Protein pkiA	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q63187	ELOA1_RAT	Transcription elongation factor B polypeptide 3	8244996	RNA polymerase II transcription factor SIII. I. Identification, purification, and properties.

Q9Y3E1	HDGR3_HUMAN	Hepatoma-derived growth factor-related protein 3	10581169	A new member of a hepatoma-derived growth factor gene family can translocate to the nucleus.

P17544	ATF7_HUMAN	Cyclic AMP-dependent transcription factor ATF-7	1694576	Isolation and characterization of two novel, closely related ATF cDNA clones from HeLa cells.

O43029	FAP1_SCHPO	L-pipecolate oxidase	16233628	Characterization of two fructosyl-amino acid oxidase homologs of Schizosaccharomyces pombe.

P63316	TNNC1_HUMAN	Troponin C, slow skeletal and cardiac muscles	15542288	Severe disease expression of cardiac troponin C and T mutations in patients with idiopathic dilated cardiomyopathy.

Q9V674	CP6G1_DROME	Cytochrome P450 6g1	11810226	DDT resistance in Drosophila correlates with Cyp6g1 over-expression and confers cross-resistance to the neonicotinoid imidacloprid.

P10591	HSP71_YEAST	Heat shock protein SSA1	11279042	The yeast hsp70 homologue Ssa is required for translation and interacts with Sis1 and Pab1 on translating ribosomes.

P53088	CTU1_YEAST	Cytoplasmic tRNA 2-thiolation protein 1	19145231	Ubiquitin-related modifier Urm1 acts as a sulphur carrier in thiolation of eukaryotic transfer RNA.

O74477	MCA1_SCHPO	Metacaspase-1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q09794	PYR1_SCHPO	Protein ura1	8590465	As in Saccharomyces cerevisiae, aspartate transcarbamoylase is assembled on a multifunctional protein including a dihydroorotase-like cryptic domain in Schizosaccharomyces pombe.

P14404	EVI1_MOUSE	MDS1 and EVI1 complex locus protein EVI1	18619962	A novel interaction between the proto-oncogene Evi1 and histone methyltransferases, SUV39H1 and G9a.

P48234	NOL10_YEAST	Ribosome biogenesis protein ENP2	12150911	90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors.

P53323	BUD32_YEAST	Serine/threonine-protein kinase BUD32	14562095	Global analysis of protein localization in budding yeast.

Q8CJ91	C209B_MOUSE	CD209 antigen-like protein B	11581173	Five mouse homologues of the human dendritic cell C-type lectin, DC- SIGN.

Q924U5	TESK2_RAT	Dual specificity testis-specific protein kinase 2	11418599	Cofilin phosphorylation and actin reorganization activities of testicular protein kinase 2 and its predominant expression in testicular Sertoli cells.

Q8AVJ9	FZD7B_XENLA	Frizzled-7-B	11477687	Xenopus frizzled-7 morphant displays defects in dorsoventral patterning and convergent extension movements during gastrulation.

P11829	ACP1_ARATH	Acyl carrier protein 1, chloroplastic	16668615	Expression of constitutive and tissue-specific acyl carrier protein isoforms in Arabidopsis.

Q9UHC6	CNTP2_HUMAN	Contactin-associated protein-like 2	11352571	The human contactin-associated protein-like 2 gene (CNTNAP2) spans over 2 Mb of DNA at chromosome 7q35.

P31572	CAIB_ECOLI	Crotonobetainyl-CoA:carnitine CoA-transferase	8188598	Cloning, nucleotide sequence, and expression of the Escherichia coli gene encoding carnitine dehydratase.

P11911	CD79A_MOUSE	B-cell antigen receptor complex-associated protein alpha chain	10587346	A role for lipid rafts in B cell antigen receptor signaling and antigen targeting.

P0ADR6	RLMM_ECOLI	Ribosomal RNA large subunit methyltransferase M	19400805	YgdE is the 2'-O-ribose methyltransferase RlmM specific for nucleotide C2498 in bacterial 23S rRNA.

O14235	POF5_SCHPO	Protein pof5	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q00888	PSG4_HUMAN	Pregnancy-specific beta-1-glycoprotein 4	1690992	The human pregnancy-specific glycoprotein genes are tightly linked on the long arm of chromosome 19 and are coordinately expressed.

P58957	G39AB_DROME	Putative gustatory receptor 39a, isoform C	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

Q03380	COMI_DICDI	Comitin	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q08I43	ERI1_SCHPO	3'-5' exonuclease eri1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P22531	SPR2E_HUMAN	Small proline-rich protein 2E	3133554	Isolation, characterization, and UV-stimulated expression of two families of genes encoding polypeptides of related structure in human epidermal keratinocytes.

P43254	COP1_ARATH	E3 ubiquitin-protein ligase COP1	12827204	LAF1 ubiquitination by COP1 controls photomorphogenesis and is stimulated by SPA1.

Q21502	MEP1_CAEEL	MOG interacting and ectopic P-granules protein 1	15689373	Sumoylation of LIN-1 promotes transcriptional repression and inhibition of vulval cell fates.

P62269	RS18_HUMAN	40S ribosomal protein S18	8441687	The human homolog of ribosomal protein S18.

Q9C0C7	AMRA1_HUMAN	Activating molecule in BECN1-regulated autophagy protein 1	17589504	Ambra1 regulates autophagy and development of the nervous system.

P17122	SPO16_YEAST	Sporulation-specific protein 16	2188099	Complementary transcripts from two genes necessary for normal meiosis in the yeast Saccharomyces cerevisiae.

P17927	CR1_HUMAN	Complement receptor type 1	2972794	Identification of distinct C3b and C4b recognition sites in the human C3b/C4b receptor (CR1, CD35) by deletion mutagenesis.

P41838	RAE1_SCHPO	Poly(A)+ RNA export protein	15990877	Homolog of BRCA2-interacting Dss1p and Uap56p link Mlo3p and Rae1p for mRNA export in fission yeast.

P02753	RET4_HUMAN	Retinol-binding protein 4	10232633	Biochemical but not clinical vitamin A deficiency results from mutations in the gene for retinol binding protein.

Q00613	HSF1_HUMAN	Heat shock factor protein 1	1871105	Molecular cloning and expression of a human heat shock factor, HSF1.

O43029	FAP1_SCHPO	L-pipecolate oxidase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q14694	UBP10_HUMAN	Ubiquitin carboxyl-terminal hydrolase 10	20096447	USP10 regulates p53 localization and stability by deubiquitinating p53.

P60228	EIF3E_HUMAN	Eukaryotic translation initiation factor 3 subunit E	17468741	Human INT6/eIF3e is required for nonsense-mediated mRNA decay.

Q7TNB4	MSTRO_MOUSE	Protein maestro	12889070	Candidate testis-determining gene, Maestro (Mro), encodes a novel HEAT repeat protein.

Q9UQK1	PPR3C_HUMAN	Protein phosphatase 1 regulatory subunit 3C	18070875	Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG).

Q9ZU11	ATB15_ARATH	Homeobox-leucine zipper protein ATHB-15	15705957	CORONA, a member of the class III homeodomain leucine zipper gene family in Arabidopsis, regulates stem cell specification and organogenesis.

P18848	ATF4_HUMAN	Cyclic AMP-dependent transcription factor ATF-4	11018027	Crystal structure of the CCAAT box/enhancer-binding protein beta activating transcription factor-4 basic leucine zipper heterodimer in the absence of DNA.

P15382	KCNE1_HUMAN	Potassium voltage-gated channel subfamily E member 1	9230439	A minK-HERG complex regulates the cardiac potassium current I(Kr).

Q13117	DAZ2_HUMAN	Deleted in azoospermia protein 2	7670487	Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA-binding protein gene.

P32614	FRDS_YEAST	Fumarate reductase	8946166	Cloning and sequencing of the gene encoding the soluble fumarate reductase from Saccharomyces cerevisiae.

Q14012	KCC1A_HUMAN	Calcium/calmodulin-dependent protein kinase type 1	7641687	Human calcium-calmodulin dependent protein kinase I: cDNA cloning, domain structure and activation by phosphorylation at threonine-177 by calcium-calmodulin dependent protein kinase I kinase.

Q9Y5J5	PHLA3_HUMAN	Pleckstrin homology-like domain family A member 3	19203586	PH domain-only protein PHLDA3 is a p53-regulated repressor of Akt.

Q9VQS7	SOB_DROME	Protein sister of odd and bowel	14597202	The odd-skipped family of zinc finger genes promotes Drosophila leg segmentation.

P20626	PLD_CORPS	Phospholipase D	2407718	Cloning, nucleotide sequence, and expression in Escherichia coli of the phospholipase D gene from Corynebacterium pseudotuberculosis.

Q03707	SRC1_YEAST	Inner nuclear membrane protein SRC1	16929305	Karyopherin-mediated import of integral inner nuclear membrane proteins.

O43681	ASNA_HUMAN	ATPase ASNA1	8884272	Isolation of the ATP-binding human homolog of the arsA component of the bacterial arsenite transporter.

P53096	HOS2_YEAST	Probable histone deacetylase HOS2	11711434	The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program.

P51610	HCFC1_HUMAN	Host cell factor 1	19188440	Association of C-terminal ubiquitin hydrolase BRCA1-associated protein 1 with cell cycle regulator host cell factor 1.

Q8CI51	PDLI5_MOUSE	PDZ and LIM domain protein 5	10833443	ENH, containing PDZ and LIM domains, heart/skeletal muscle-specific protein, associates with cytoskeletal proteins through the PDZ domain.

P40085	TAPT1_YEAST	Protein TAPT1 homolog	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

O54949	NLK_MOUSE	Serine/threonine-protein kinase NLK	15004007	Role of the TAK1-NLK-STAT3 pathway in TGF-beta-mediated mesoderm induction.

O73823	TAL1_XENLA	T-cell acute lymphocytic leukemia protein 1	9636076	SCL specifies hematopoietic mesoderm in Xenopus embryos.

P36551	HEM6_HUMAN	Coproporphyrinogen-III oxidase, mitochondrial	16176984	Structural basis of hereditary coproporphyria.

P19490	GRIA1_RAT	Glutamate receptor 1	9677374	SAP97 is associated with the alpha-amino-3-hydroxy-5-methylisoxazole- 4-propionic acid receptor GluR1 subunit.

P04786	TOP1_YEAST	DNA topoisomerase 1	2989818	Cloning, characterization, and sequence of the yeast DNA topoisomerase I gene.

Q8R4I1	ATX7_MOUSE	Ataxin-7	12039035	Cloning and expression analysis of the murine homolog of the spinocerebellar ataxia type 7 (SCA7) gene.

Q12692	H2AZ_YEAST	Histone H2A.Z	11000274	Histone H2A.Z has a conserved function that is distinct from that of the major H2A sequence variants.

Q9HDY9	MAM3_SCHPO	M cell-type agglutination protein mam3	17032641	Global roles of Ste11p, cell type, and pheromone in the control of gene expression during early sexual differentiation in fission yeast.

Q90X44	NRF1_DANRE	Nuclear respiratory factor 1	9778497	Not really finished is crucial for development of the zebrafish outer retina and encodes a transcription factor highly homologous to human nuclear respiratory factor-1 and avian initiation binding repressor.

Q9Y277	VDAC3_HUMAN	Voltage-dependent anion-selective channel protein 3	9781040	Isolation of a novel human voltage-dependent anion channel gene.

P54860	UFD2_YEAST	E4 ubiquitin-protein ligase UFD2	7615550	A proteolytic pathway that recognizes ubiquitin as a degradation signal.

Q940H6	SRK2E_ARATH	Serine/threonine-protein kinase SRK2E	12047634	Use of infrared thermal imaging to isolate Arabidopsis mutants defective in stomatal regulation.

O70467	ANM3_RAT	Protein arginine N-methyltransferase 3	9642256	PRMT 3, a type I protein arginine N-methyltransferase that differs from PRMT1 in its oligomerization, subcellular localization, substrate specificity, and regulation.

Q6J5K9	ARMI_DROME	Probable RNA helicase armi	15035985	RISC assembly defects in the Drosophila RNAi mutant armitage.

Q10133	RHO2_SCHPO	GTP-binding protein rho2	11102532	Schizosaccharomyces pombe rho2p GTPase regulates cell wall alpha- glucan biosynthesis through the protein kinase pck2p.

P53137	CUE3_YEAST	CUE domain-containing protein 3	14562095	Global analysis of protein localization in budding yeast.

O94778	AQP8_HUMAN	Aquaporin-8	9806845	Cloning and functional expression of human aquaporin8 cDNA and analysis of its gene.

Q03626	MUG1_RAT	Murinoglobulin-1	2831216	Sequence and acute phase regulation of rat alpha 1-inhibitor III messenger RNA.

P30926	ACHB4_HUMAN	Neuronal acetylcholine receptor subunit beta-4	11742001	Transcription factors NF-Y and Sp1 are important determinants of the promoter activity of the bovine and human neuronal nicotinic receptor beta 4 subunit genes.

P81900	KAPR2_DROME	cAMP-dependent protein kinase type II regulatory subunit	10781603	Type II cAMP-dependent protein kinase-deficient Drosophila are viable but show developmental, circadian, and drug response phenotypes.

Q14980	NUMA1_HUMAN	Nuclear mitotic apparatus protein 1	1541636	Primary structure of NuMA, an intranuclear protein that defines a novel pathway for segregation of proteins at mitosis.

Q9SS04	GSOX1_ARATH	Flavin-containing monooxygenase FMO GS-OX1	17461789	Identification of a flavin-monooxygenase as the S-oxygenating enzyme in aliphatic glucosinolate biosynthesis in Arabidopsis.

P27882	ERV1_YEAST	Mitochondrial FAD-linked sulfhydryl oxidase ERV1	10899311	Erv1p from Saccharomyces cerevisiae is a FAD-linked sulfhydryl oxidase.

O00429	DNM1L_HUMAN	Dynamin-1-like protein	9731200	Human dynamin-like protein interacts with the glycogen synthase kinase 3beta.

Q9NRE1	MMP26_HUMAN	Matrix metalloproteinase-26	10801841	Identification and characterization of Homo sapiens endometase (matrix metalloproteinase-26) from endometrial tumor.

P52892	ALAT_YEAST	Probable alanine aminotransferase	14562095	Global analysis of protein localization in budding yeast.

P70697	DCUP_MOUSE	Uroporphyrinogen decarboxylase	8661721	Mouse uroporphyrinogen decarboxylase: cDNA cloning, expression, and mapping.

Q9UTB6	SDS3_SCHPO	Transcriptional regulatory protein sds3	17450151	Distinct roles of HDAC complexes in promoter silencing, antisense suppression and DNA damage protection.

Q45VK7	DYHC2_MOUSE	Cytoplasmic dynein 2 heavy chain 1	16061793	Cilia and Hedgehog responsiveness in the mouse.

Q92783	STAM1_HUMAN	Signal transducing adapter molecule 1	8780729	Cloning of a novel signal-transducing adaptor molecule containing an SH3 domain and ITAM.

P35321	SPR1A_HUMAN	Cornifin-A	8325635	Molecular characterization and evolution of the SPRR family of keratinocyte differentiation markers encoding small proline-rich proteins.

P40208	GID8_YEAST	Glucose-induced degradation protein 8	15590836	Gid8p (Dcr1p) and Dcr2p function in a common pathway to promote START completion in Saccharomyces cerevisiae.

P17028	ZNF24_HUMAN	Zinc finger protein 24	10585455	Molecular cloning of six novel Kruppel-like zinc finger genes from hematopoietic cells and identification of a novel transregulatory domain KRNB.

Q14188	TFDP2_HUMAN	Transcription factor Dp-2	16360038	Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release.

P53694	CWL1_SCHPO	Cell lysis protein cwl1	8873452	Characterization of cwl1+, a gene from Schizosaccharomyces pombe whose overexpression causes cell lysis.

O95747	OXSR1_HUMAN	Serine/threonine-protein kinase OSR1	10083736	Isolation and characterization of a novel serine threonine kinase gene on chromosome 3p22-21.3.

Q8TAS1	UHMK1_HUMAN	Serine/threonine-protein kinase Kist	12093740	A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression.

Q9FIZ3	GSO2_ARATH	LRR receptor-like serine/threonine-protein kinase GSO2	18088309	GASSHO1 and GASSHO2 encoding a putative leucine-rich repeat transmembrane-type receptor kinase are essential for the normal development of the epidermal surface in Arabidopsis embryos.

Q9V4Z9	LINES_DROME	Protein lines	10837029	Tissue- and stage-specific modulation of Wingless signaling by the segment polarity gene lines.

O14170	POP2_SCHPO	WD repeat-containing protein pop2	10209119	F-box/WD-repeat proteins pop1p and Sud1p/Pop2p form complexes that bind and direct the proteolysis of cdc18p.

Q9VNS0	MAEL_DROME	Protein maelstrom	12538514	Maelstrom, a Drosophila spindle-class gene, encodes a protein that colocalizes with Vasa and RDE1/AGO1 homolog, Aubergine, in nuage.

Q9UNW1	MINP1_HUMAN	Multiple inositol polyphosphate phosphatase 1	10087200	Multiple inositol polyphosphate phosphatase: evolution as a distinct group within the histidine phosphatase family and chromosomal localization of the human and mouse genes to chromosomes 10q23 and 19.

O94714	SPT2_SCHPO	Protein spt2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P85003	CYCLE_ANNCH	Cyclopeptide E	16040066	Two cyclopeptides from the seeds of Annona cherimola.

Q99828	CIB1_HUMAN	Calcium and integrin-binding protein 1	9372844	Interaction between DNA-dependent protein kinase and a novel protein, KIP.

P30518	V2R_HUMAN	Vasopressin V2 receptor	9224808	Palmitoylation of the V2 vasopressin receptor.

Q12028	AP1G1_YEAST	AP-1 complex subunit gamma-1	10564262	Adaptor complex-independent clathrin function in yeast.

Q14160	SCRIB_HUMAN	Protein scribble homolog	16611247	Human scribble, a novel tumor suppressor identified as a target of high-risk HPV E6 for ubiquitin-mediated degradation, interacts with adenomatous polyposis coli.

Q7XUN2	MAD17_ORYSJ	MADS-box transcription factor 17	10444103	Determination of the motif responsible for interaction between the rice APETALA1/AGAMOUS-LIKE9 family proteins using a yeast two-hybrid system.

Q8IEF6	MYB1_PLAF7	Myb1 protein	15663925	PfMyb1, a Plasmodium falciparum transcription factor, is required for intra-erythrocytic growth and controls key genes for cell cycle regulation.

P08865	RSSA_HUMAN	40S ribosomal protein SA	10079194	Ribosome-associated protein LBP/p40 binds to S21 protein of 40S ribosome: analysis using a yeast two-hybrid system.

P81912	OR23A_DROME	Odorant receptor 23a	10069338	A novel family of divergent seven-transmembrane proteins: candidate odorant receptors in Drosophila.

Q39111	GAOX2_ARATH	Gibberellin 20 oxidase 2	7630935	Isolation and expression of three gibberellin 20-oxidase cDNA clones from Arabidopsis.

Q9S7I0	TADA_ARATH	tRNA-specific adenosine deaminase, chloroplastic	19460869	Identification of the chloroplast adenosine-to-inosine tRNA editing enzyme.

P40189	IL6RB_HUMAN	Interleukin-6 receptor subunit beta	8999038	Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation.

Q9P6R1	VRP1_SCHPO	Verprolin	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8MML6	VATH_DICDI	V-type proton ATPase subunit H	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q9UT32	RL1DB_SCHPO	Putative ribosome biogenesis protein C8F11.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q08J23	NSUN2_HUMAN	tRNA (cytosine-5-)-methyltransferase NSUN2	17071714	Identification of human tRNA:m5C methyltransferase catalysing intron- dependent m5C formation in the first position of the anticodon of the pre-tRNA Leu (CAA).

O96013	PAK4_HUMAN	Serine/threonine-protein kinase PAK 4	9822598	PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia.

Q8J025	APCD1_HUMAN	Protein APCDD1	20393562	APCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplex.

Q9VM64	IHOG_DROME	Interference hedgehog	16630821	The ihog cell-surface proteins bind Hedgehog and mediate pathway activation.

Q14201	BTG3_HUMAN	Protein BTG3	9632145	ANA, a novel member of Tob/BTG1 family, is expressed in the ventricular zone of the developing central nervous system.

Q9M7Q2	AI5L7_ARATH	ABSCISIC ACID-INSENSITIVE 5-like protein 7	16463099	Transcriptional regulation of ABI3- and ABA-responsive genes including RD29B and RD29A in seeds, germinating embryos, and seedlings of Arabidopsis.

Q06549	CDD_YEAST	Cytidine deaminase	10501935	New insights into the pyrimidine salvage pathway of Saccharomyces cerevisiae: requirement of six genes for cytidine metabolism.

O60488	ACSL4_HUMAN	Long-chain-fatty-acid--CoA ligase 4	9480748	FACL4, a new gene encoding long-chain acyl-CoA synthetase 4, is deleted in a family with Alport syndrome, elliptocytosis, and mental retardation.

P0AEU7	SKP_ECOLI	Chaperone protein skp	8730870	A periplasmic protein (Skp) of Escherichia coli selectively binds a class of outer membrane proteins.

P31948	STIP1_HUMAN	Stress-induced-phosphoprotein 1	1569099	Molecular cloning and expression of a transformation-sensitive human protein containing the TPR motif and sharing identity to the stress- inducible yeast protein STI1.

Q9JLA2	IL1F6_MOUSE	Interleukin-1 family member 6	10744718	Identification and initial characterization of four novel members of the interleukin-1 family.

P00966	ASSY_HUMAN	Argininosuccinate synthase	2358466	Heterogeneity of mutations in argininosuccinate synthetase causing human citrullinemia.

P34208	CHK1_SCHPO	Serine/threonine-protein kinase chk1	8497322	Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2.

P38574	UPK3A_BOVIN	Uroplakin-3a	12475947	Specific heterodimer formation is a prerequisite for uroplakins to exit from the endoplasmic reticulum.

Q53HV7	SMUG1_HUMAN	Single-strand selective monofunctional uracil DNA glycosylase	12718543	Mammalian 5-formyluracil-DNA glycosylase. 2. Role of SMUG1 uracil-DNA glycosylase in repair of 5-formyluracil and other oxidized and deaminated base lesions.

Q9LD43	ACCA_ARATH	Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

P23803	ODD_DROME	Protein odd-skipped	2120051	Molecular analysis of odd-skipped, a zinc finger encoding segmentation gene with a novel pair-rule expression pattern.

Q9Y802	LSD1_SCHPO	Lysine-specific histone demethylase 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P42259	HTR2_NATPH	Sensory rhodopsin II transducer	12368857	Molecular basis of transmembrane signalling by sensory rhodopsin II- transducer complex.

Q15287	RNPS1_HUMAN	RNA-binding protein with serine-rich domain 1	9580558	The RNP protein, RNPS1, associates with specific isoforms of the p34cdc2-related PITSLRE protein kinases in vivo.

O94742	SEM1_YEAST	26S proteasome complex subunit SEM1	9927667	SEM1, a homologue of the split hand/split foot malformation candidate gene Dss1, regulates exocytosis and pseudohyphal differentiation in yeast.

Q9WTN6	S22AL_MOUSE	Solute carrier family 22 member 21	11010964	Molecular and functional characterization of organic cation/carnitine transporter family in mice.

P70033	NR6A1_XENLA	Nuclear receptor subfamily 6 group A member 1	9025060	xGCNF, a nuclear orphan receptor is expressed during neurulation in Xenopus laevis.

P32301	GLP1R_RAT	Glucagon-like peptide 1 receptor	1326760	Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1.

P25045	LCB1_YEAST	Serine palmitoyltransferase 1	20182505	Orm family proteins mediate sphingolipid homeostasis.

Q9FIJ6	ACCR4_ARATH	Serine/threonine-protein kinase-like protein CCR4	18539132	Dimerization properties of the transmembrane domains of Arabidopsis CRINKLY4 receptor-like kinase and homologs.

Q99590	SRSIP_HUMAN	SRSF2-interacting protein	9447963	Sip1, a novel RS domain-containing protein essential for pre-mRNA splicing.

Q9NSE2	CISH_HUMAN	Cytokine-inducible SH2-containing protein	9465889	Molecular cloning of CISH, chromosome assignment to 3p21.3, and analysis of expression in fetal and adult tissues.

P40847	SAP1_SCHPO	Switch-activating protein 1	16166653	The mating type switch-activating protein Sap1 Is required for replication fork arrest at the rRNA genes of fission yeast.

Q869Y7	ODO2_DICDI	Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

P0AGK8	ISCR_ECOLI	HTH-type transcriptional regulator iscR	11742080	IscR, an Fe-S cluster-containing transcription factor, represses expression of Escherichia coli genes encoding Fe-S cluster assembly proteins.

Q9M8Y5	LTL1_ARATH	GDSL esterase/lipase LTL1	16930315	Overexpression of Arabidopsis thaliana LTL1, a salt-induced gene encoding a GDSL-motif lipase, increases salt tolerance in yeast and transgenic plants.

P38248	ECM33_YEAST	Cell wall protein ECM33	15781460	Comprehensive proteomic analysis of Saccharomyces cerevisiae cell walls: identification of proteins covalently attached via glycosylphosphatidylinositol remnants or mild alkali-sensitive linkages.

P56542	DNS2A_MOUSE	Deoxyribonuclease-2-alpha	11375492	Requirement of DNase II for definitive erythropoiesis in the mouse fetal liver.

Q6PST4	ATLA1_RAT	Atlastin-1	14506257	Cellular localization, oligomerization, and membrane association of the hereditary spastic paraplegia 3A (SPG3A) protein atlastin.

O74985	NAT1_SCHPO	N-terminal acetyltransferase A complex subunit nat1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UTR5	RGF2_SCHPO	Rho1 guanine nucleotide exchange factor 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P26453	BASI_RAT	Basigin	12141934	Basigin expression and hormonal regulation in the rat uterus during the peri-implantation period.

P83660	C146_CYPDO	Cd-146 peptide	11306139	Isolation and sequence determination of peptides in the venom of the spider wasp (Cyphononyx dorsalis) guided by matrix-assisted laser desorption/ionization time of flight (MALDI-TOF) mass spectrometry.

P86092	VMLEB_BOTLC	Zinc metalloproteinase leucurolysin-B	17963685	Structural and functional characterization of a P-III metalloproteinase, leucurolysin-B, from Bothrops leucurus venom.

Q5BLX8	WDR83_RAT	WD repeat domain-containing protein 83	16407229	The novel WD-repeat protein Morg1 acts as a molecular scaffold for hypoxia-inducible factor prolyl hydroxylase 3 (PHD3).

P08069	IGF1R_HUMAN	Insulin-like growth factor 1 receptor	1846292	Interaction of the alpha beta dimers of the insulin-like growth factor I receptor is required for receptor autophosphorylation.

P53370	NUDT6_HUMAN	Nucleoside diphosphate-linked moiety X motif 6	7984147	Identification and characterization of an antisense RNA transcript (gfg) from the human basic fibroblast growth factor gene.

P57730	CAR18_HUMAN	Caspase recruitment domain-containing protein 18	11051551	ICEBERG: a novel inhibitor of interleukin-1beta generation.

P31327	CPSM_HUMAN	Carbamoyl-phosphate synthase [ammonia], mitochondrial	9711878	Prenatal diagnosis of carbamoyl phosphate synthetase I deficiency by identification of a missense mutation in CPS1.

Q9Y169	EXT2_DROME	Exostosin-2	15056609	Abrogation of heparan sulfate synthesis in Drosophila disrupts the Wingless, Hedgehog and Decapentaplegic signaling pathways.

Q9Y5S9	RBM8A_HUMAN	RNA-binding protein 8A	10662555	MAGOH interacts with a novel RNA-binding protein.

Q08945	SSRP1_HUMAN	FACT complex subunit SSRP1	19836239	UIF, a new mRNA export adaptor that works together with REF/ALY, requires FACT for recruitment to mRNA.

P46939	UTRO_HUMAN	Utrophin	16777071	Interactions of intermediate filament protein synemin with dystrophin and utrophin.

P32323	AGA1_YEAST	A-agglutinin anchorage subunit	2072914	The AGA1 product is involved in cell surface attachment of the Saccharomyces cerevisiae cell adhesion glycoprotein a-agglutinin.

P49454	CENPF_HUMAN	Centromere protein F	12974617	Mitosin/CENP-F is a conserved kinetochore protein subjected to cytoplasmic dynein-mediated poleward transport.

Q9UTK6	YKR3_SCHPO	G-patch domain-containing protein C1486.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8IUQ4	SIAH1_HUMAN	E3 ubiquitin-protein ligase SIAH1	9334332	Mammalian homologs of seven in absentia regulate DCC via the ubiquitin-proteasome pathway.

Q8IU54	IL29_HUMAN	Interleukin-29	12483210	IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex.

Q6PFW1	VIP1_HUMAN	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1	17702752	Purification, sequencing, and molecular identification of a mammalian PP-InsP5 kinase that is activated when cells are exposed to hyperosmotic stress.

Q14315	FLNC_HUMAN	Filamin-C	11038172	Indications for a novel muscular dystrophy pathway: gamma-filamin, the muscle-specific filamin isoform, interacts with myotilin.

Q9P6P3	PPK15_SCHPO	Serine/threonine-protein kinase ppk15	15821139	Systematic deletion analysis of fission yeast protein kinases.

Q13702	RAPSN_HUMAN	43 kDa receptor-associated protein of the synapse	8812503	Cloning of cDNA encoding human rapsyn and mapping of the RAPSN gene locus to chromosome 11p11.2-p11.1.

P07320	CRGD_HUMAN	Gamma-crystallin D	12011157	Novel mutations in the gamma-crystallin genes cause autosomal dominant congenital cataracts.

P30182	TOP2_ARATH	DNA topoisomerase 2	7838729	Abundance of nuclear DNA topoisomerase II is correlated with proliferation in Arabidopsis thaliana.

Q3SZK1	AAMP_BOVIN	Angio-associated migratory cell protein	11969303	Extracellular angio-associated migratory cell protein plays a positive role in angiogenesis and is regulated by astrocytes in coculture.

P52298	NCBP2_HUMAN	Nuclear cap-binding protein subunit 2	7651522	A cap-binding protein complex mediating U snRNA export.

O13286	SRW1_SCHPO	WD repeat-containing protein srw1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12792	TWF1_HUMAN	Twinfilin-1	7507208	Prokaryotic expression cloning of a novel human tyrosine kinase.

Q92985	IRF7_HUMAN	Interferon regulatory factor 7	9315633	IRF-7, a new interferon regulatory factor associated with Epstein- Barr virus latency.

P33277	GAP1_SCHPO	GTPase-activating protein	1883874	sar1, a gene from Schizosaccharomyces pombe encoding a protein that regulates ras1.

P0CB05	CEP63_CHICK	Centrosomal protein of 63 kDa	19182792	An ATM- and ATR-dependent checkpoint inactivates spindle assembly by targeting CEP63.

Q8STE5	CED12_CAEEL	Cell death abnormality protein 12	11703939	The C. elegans PH domain protein CED-12 regulates cytoskeletal reorganization via a Rho/Rac GTPase signaling pathway.

Q15645	TRP13_HUMAN	Thyroid receptor-interacting protein 13	7776974	Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor.

Q99640	PMYT1_HUMAN	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	9001210	The human Myt1 kinase preferentially phosphorylates Cdc2 on threonine 14 and localizes to the endoplasmic reticulum and Golgi complex.

Q9CRZ8	TSPO2_MOUSE	Translocator protein 2	19729679	Translocator protein 2 is involved in cholesterol redistribution during erythropoiesis.

P47866	CRFR2_RAT	Corticotropin-releasing factor receptor 2	7846062	Cloning and characterization of a functionally distinct corticotropin-releasing factor receptor subtype from rat brain.

Q9Y663	HS3SA_HUMAN	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1	9988767	Multiple isoforms of heparan sulfate D-glucosaminyl 3-O- sulfotransferase. Isolation, characterization, and expression of human cDNAs and identification of distinct genomic loci.

Q9FH02	FTSH5_ARATH	ATP-dependent zinc metalloprotease FTSH 5, chloroplastic	16157880	AtFtsH6 is involved in the degradation of the light-harvesting complex II during high-light acclimation and senescence.

P32838	PP2A4_YEAST	Serine/threonine-protein phosphatase PP2A-like PPG1	7678255	The gene PPG encodes a novel yeast protein phosphatase involved in glycogen accumulation.

Q03063	DIG1_YEAST	Down-regulator of invasive growth 1	9094309	Regulation of the mating pheromone and invasive growth responses in yeast by two MAP kinase substrates.

Q9NTI5	PDS5B_HUMAN	Sister chromatid cohesion protein PDS5 homolog B	15855230	Functional contribution of Pds5 to cohesin-mediated cohesion in human cells and Xenopus egg extracts.

P83369	LSM11_HUMAN	U7 snRNA-associated Sm-like protein LSm11	16714279	Conserved zinc fingers mediate multiple functions of ZFP100, a U7snRNP associated protein.

P40541	SCC3_YEAST	Cohesin subunit SCC3	9990856	Yeast cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication.

Q9VDW6	DMDA_DROME	Dystrophin, isoforms A/C/F/G/H	18093579	The detached locus encodes Drosophila Dystrophin, which acts with other components of the Dystrophin Associated Protein Complex to influence intercellular signalling in developing wing veins.

Q9Y6E7	SIRT4_HUMAN	NAD-dependent ADP-ribosyltransferase sirtuin-4	10381378	Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity.

P0C2W1	FBSP1_HUMAN	F-box/SPRY domain-containing protein 1	19581926	The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73.

O75027	ABCB7_HUMAN	ATP-binding cassette sub-family B member 7, mitochondrial	9621516	Cloning and chromosomal mapping of a novel ABC transporter gene (hABC7), a candidate for X-linked sideroblastic anemia with spinocerebellar ataxia.

P06129	BTUB_ECOLI	Vitamin B12 transporter BtuB	14528295	The structure of BtuB with bound colicin E3 R-domain implies a translocon.

P51665	PSD7_HUMAN	26S proteasome non-ATPase regulatory subunit 7	7755639	cDNA cloning of p40, a regulatory subunit of the human 26S proteasome, and a homolog of the Mov-34 gene product.

P19544	WT1_HUMAN	Wilms tumor protein	7862533	High affinity binding sites for the Wilms' tumour suppressor protein WT1.

P24895	NU3M_CAEEL	NADH-ubiquinone oxidoreductase chain 3	1551572	The mitochondrial genomes of two nematodes, Caenorhabditis elegans and Ascaris suum.

P25582	SPB1_YEAST	AdoMet-dependent rRNA methyltransferase SPB1	15546625	Spb1p-directed formation of Gm2922 in the ribosome catalytic center occurs at a late processing stage.

P34791	CP20C_ARATH	Peptidyl-prolyl cis-trans isomerase CYP20-3, chloroplastic	12938931	Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis.

Q12006	PFA4_YEAST	Palmitoyltransferase PFA4	16186255	The vacuolar DHHC-CRD protein Pfa3p is a protein acyltransferase for Vac8p.

Q8GYY1	HSFA3_ARATH	Heat stress transcription factor A-3	17999647	A cascade of transcription factor DREB2A and heat stress transcription factor HsfA3 regulates the heat stress response of Arabidopsis.

Q94AI7	TPL_ARATH	Protein TOPLESS	16461579	Analysis of the transcription factor WUSCHEL and its functional homologue in Antirrhinum reveals a potential mechanism for their roles in meristem maintenance.

P68036	UB2L3_HUMAN	Ubiquitin-conjugating enzyme E2 L3	16709802	NK lytic-associated molecule, involved in NK cytotoxic function, is an E3 ligase.

P26717	NKG2C_HUMAN	NKG2-C type II integral membrane protein	2007850	DNA sequence analysis of NKG2, a family of related cDNA clones encoding type II integral membrane proteins on human natural killer cells.

P62826	RAN_HUMAN	GTP-binding nuclear protein Ran	10353245	Structure of the nuclear transport complex karyopherin-beta2-Ran x GppNHp.

Q7YZH1	RNO_DROME	PHD finger protein rhinoceros	14704181	The novel plant homeodomain protein rhinoceros antagonizes Ras signaling in the Drosophila eye.

Q86U86	PB1_HUMAN	Protein polybromo-1	11078522	The human SWI/SNF-B chromatin-remodeling complex is related to yeast rsc and localizes at kinetochores of mitotic chromosomes.

Q9VAS7	INX3_DROME	Innexin inx3	10888681	Two Drosophila innexins are expressed in overlapping domains and cooperate to form gap-junction channels.

O77150	IM02_DROME	Immune-induced peptide 2	9736738	Differential display of peptides induced during the immune response of Drosophila: a matrix-assisted laser desorption ionization time-of- flight mass spectrometry study.

P36122	BCH2_YEAST	Protein BCH2	16498409	Arf1p, Chs5p and the ChAPs are required for export of specialized cargo from the Golgi.

P31755	OCH1_YEAST	Initiation-specific alpha-1,6-mannosyltransferase	1628616	OCH1 encodes a novel membrane bound mannosyltransferase: outer chain elongation of asparagine-linked oligosaccharides.

Q4FZ76	RTN2_XENLA	Reticulon-2	15765506	Identification and expression of XRTN2 and XRTN3 during Xenopus development.

Q06102	YTH1_YEAST	mRNA 3'-end-processing protein YTH1	9224719	The 30-kD subunit of mammalian cleavage and polyadenylation specificity factor and its yeast homolog are RNA-binding zinc finger proteins.

Q8N3U4	STAG2_HUMAN	Cohesin subunit SA-2	9305759	SA-1, a nuclear protein encoded by one member of a novel gene family: molecular cloning and detection in hemopoietic organs.

P15313	VATB1_HUMAN	V-type proton ATPase subunit B, kidney isoform	9916796	Mutations in the gene encoding B1 subunit of H+-ATPase cause renal tubular acidosis with sensorineural deafness.

P47775	GPR12_HUMAN	G-protein coupled receptor 12	8530049	Molecular cloning and chromosomal localization of human genes encoding three closely related G protein-coupled receptors.

O75940	SPF30_HUMAN	Survival of motor neuron-related-splicing factor 30	9731529	Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex.

Q9UI08	EVL_HUMAN	Ena/VASP-like protein	10993894	The orthologous human and murine semaphorin 6A-1 proteins (SEMA6A- 1/Sema6A-1) bind to the enabled/vasodilator-stimulated phosphoprotein- like protein (EVL) via a novel carboxyl-terminal zyxin-like domain.

P49796	RGS3_HUMAN	Regulator of G-protein signaling 3	9858594	RGS3 inhibits G protein-mediated signaling via translocation to the membrane and binding to Galpha11.

P70580	PGRC1_RAT	Membrane-associated progesterone receptor component 1	10656251	Cloning and expression of VEMA: a novel ventral midline antigen in the rat CNS.

Q8NFT8	DNER_HUMAN	Delta and Notch-like epidermal growth factor-related receptor	11950833	Delta/notch-like epidermal growth factor (EGF)-related receptor, a novel EGF-like repeat-containing protein targeted to dendrites of developing and adult central nervous system neurons.

Q08257	QOR_HUMAN	Quinone oxidoreductase	17497241	Human and yeast zeta-crystallins bind AU-rich elements in RNA.

P09681	GIP_HUMAN	Gastric inhibitory polypeptide	2890159	Sequence of an intestinal cDNA encoding human gastric inhibitory polypeptide precursor.

O95661	DIRA3_HUMAN	GTP-binding protein Di-Ras3	9874798	NOEY2 (ARHI), an imprinted putative tumor suppressor gene in ovarian and breast carcinomas.

Q55BN8	NEK2_DICDI	Probable serine/threonine-protein kinase nek2	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P42641	OBG_ECOLI	GTPase ObgE/CgtA	15836769	The GTP binding protein Obg homolog ObgE is involved in ribosome maturation.

Q9NR22	ANM8_HUMAN	Protein arginine N-methyltransferase 8	16051612	PRMT8, a new membrane-bound tissue-specific member of the protein arginine methyltransferase family.

P16235	LSHR_RAT	Lutropin-choriogonadotropic hormone receptor	1714448	Asp383 in the second transmembrane domain of the lutropin receptor is important for high affinity hormone binding and cAMP production.

P48029	SC6A8_HUMAN	Sodium- and chloride-dependent creatine transporter 1	7953292	Cloning, pharmacological characterization, and genomic localization of the human creatine transporter.

P32340	NDI1_YEAST	Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial	11502169	Yeast mitochondrial dehydrogenases are associated in a supramolecular complex.

P0AE76	COBU_ECOLI	Bifunctional adenosylcobalamin biosynthesis protein CobU	7592411	The cobalamin (coenzyme B12) biosynthetic genes of Escherichia coli.

Q54LP7	UB2J2_DICDI	Ubiquitin-conjugating enzyme E2 J2	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

O84944	SSEA_SALTY	Type III secretion system chaperone sseA	9786193	Genes encoding putative effector proteins of the type III secretion system of Salmonella pathogenicity island 2 are required for bacterial virulence and proliferation in macrophages.

Q969M2	CXA10_HUMAN	Gap junction alpha-10 protein	12881038	Expression profiles of the novel human connexin genes hCx30.2, hCx40.1, and hCx62 differ from their putative mouse orthologues.

O14093	VPS54_SCHPO	Vacuolar protein sorting-associated protein 54	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9US55	GLU2A_SCHPO	Glucosidase 2 subunit alpha	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Z1Z1	E2AK3_RAT	Eukaryotic translation initiation factor 2-alpha kinase 3	9819435	Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control.

Q03557	GATH_YEAST	Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

Q06707	SWC7_YEAST	SWR1-complex protein 7	14690608	A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1.

Q9H1D0	TRPV6_HUMAN	Transient receptor potential cation channel subfamily V member 6	11278579	Expression of CaT-like, a novel calcium selective channel, correlates with the malignancy of prostate cancer.

Q9UTT1	UBP21_SCHPO	Ubiquitin carboxyl-terminal hydrolase 21	11919719	The deubiquitinating enzyme Ubp21p of fission yeast stabilizes a mutant form of protein kinase Prp4p.

Q9XYZ5	DDB1_DROME	DNA damage-binding protein 1	16428319	Drosophila damaged DNA binding protein 1 contributes to genome stability in somatic cells.

O94590	SEC1_SCHPO	Protein transport protein sec1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9U7C9	NUCMR_DICDI	Nucleomorphin	15325281	Dictyostelium calcium-binding protein 4a interacts with nucleomorphin, a BRCT-domain protein that regulates nuclear number.

P09603	CSF1_HUMAN	Macrophage colony-stimulating factor 1	2460758	Human macrophage-colony stimulating factor: alternative RNA and protein processing from a single gene.

O60494	CUBN_HUMAN	Cubilin	11717447	Cubilin dysfunction causes abnormal metabolism of the steroid hormone 25(OH) vitamin D(3).

Q96PM5	ZN363_HUMAN	RING finger and CHY zinc finger domain-containing protein 1	19043414	Molecular basis of Pirh2-mediated p53 ubiquitylation.

Q12887	COX10_HUMAN	Protoheme IX farnesyltransferase, mitochondrial	10767350	A mutation in the human heme A:farnesyltransferase gene (COX10) causes cytochrome c oxidase deficiency.

B7ZAQ6	GPHRA_HUMAN	Golgi pH regulator A	18794847	GPHR is a novel anion channel critical for acidification and functions of the Golgi apparatus.

Q9Z2Y3	HOME1_MOUSE	Homer protein homolog 1	12176012	An N-terminal sequence specific for a novel Homer1 isoform controls trafficking of group I metabotropic glutamate receptor in mammalian cells.

P38627	URA8_YEAST	CTP synthase 2	7559626	Differential biochemical regulation of the URA7- and URA8-encoded CTP synthetases from Saccharomyces cerevisiae.

Q9UUL2	RAD57_SCHPO	DNA repair protein rhp57	10747044	A recombination repair gene of Schizosaccharomyces pombe, rhp57, is a functional homolog of the Saccharomyces cerevisiae RAD57 gene and is phylogenetically related to the human XRCC3 gene.

O75489	NDUS3_HUMAN	NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial	9647766	cDNA sequence and chromosomal localization of the remaining three human nuclear encoded iron sulphur protein (IP) subunits of complex I: the human IP fraction is completed.

Q92844	TANK_HUMAN	TRAF family member-associated NF-kappa-B activator	8710854	I-TRAF is a novel TRAF-interacting protein that regulates TRAF- mediated signal transduction.

Q16586	SGCA_HUMAN	Alpha-sarcoglycan	8069911	Missense mutations in the adhalin gene linked to autosomal recessive muscular dystrophy.

P34791	CP20C_ARATH	Peptidyl-prolyl cis-trans isomerase CYP20-3, chloroplastic	8132503	Cloning and characterization of chloroplast and cytosolic forms of cyclophilin from Arabidopsis thaliana.

P35131	UBC8_ARATH	Ubiquitin-conjugating enzyme E2 8	16792696	Upregulation of an Arabidopsis RING-H2 gene, XERICO, confers drought tolerance through increased abscisic acid biosynthesis.

Q9HGL0	YHLC_SCHPO	Uncharacterized ubiquitin-like protein C800.12c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NP91	S6A20_HUMAN	Sodium- and chloride-dependent transporter XTRP3	15632147	Identification of mammalian proline transporter SIT1 (SLC6A20) with characteristics of classical system imino.

Q02732	CTF19_YEAST	Central kinetochore subunit CTF19	10189365	Ctf19p: a novel kinetochore protein in Saccharomyces cerevisiae and a potential link between the kinetochore and mitotic spindle.

P47049	UBX6_YEAST	UBX domain-containing protein 6	15258615	Shp1 and Ubx2 are adaptors of Cdc48 involved in ubiquitin-dependent protein degradation.

Q9SV36	ARK1_ARATH	Armadillo repeat-containing kinesin-like protein 1	17971038	Armadillo repeat-containing kinesins and a NIMA-related kinase are required for epidermal-cell morphogenesis in Arabidopsis.

Q9Y252	RNF6_HUMAN	E3 ubiquitin-protein ligase RNF6	19345326	Regulation of androgen receptor transcriptional activity and specificity by RNF6-induced ubiquitination.

Q9NPG2	NGB_HUMAN	Neuroglobin	11029004	A vertebrate globin expressed in the brain.

P97564	GPAT1_RAT	Glycerol-3-phosphate acyltransferase 1, mitochondrial	10446428	Rat sn-glycerol-3-phosphate acyltransferase: molecular cloning and characterization of the cDNA and expressed protein.

Q9PT61	OTX5B_XENLA	Homeobox protein otx5-B	12588845	XOtx5b and XOtx2 regulate photoreceptor and bipolar fates in the Xenopus retina.

Q12114	CHS5_YEAST	Chitin biosynthesis protein CHS5	9008706	Targeting of chitin synthase 3 to polarized growth sites in yeast requires Chs5p and Myo2p.

P43354	NR4A2_HUMAN	Nuclear receptor subfamily 4 group A member 2	7877627	NOT, a human immediate-early response gene closely related to the steroid/thyroid hormone receptor NAK1/TR3.

P21170	SPEA_ECOLI	Biosynthetic arginine decarboxylase	4571773	Biosynthetic arginine decarboxylase from Escherichia coli. Purification and properties.

Q1MTN3	PIC1_SCHPO	Inner centromere protein-related protein pic1	11950927	The Schizosaccharomyces pombe aurora-related kinase Ark1 interacts with the inner centromere protein Pic1 and mediates chromosome segregation and cytokinesis.

Q9VC27	NICA_DROME	Nicastrin	11782315	Nicastrin is required for gamma-secretase cleavage of the Drosophila Notch receptor.

P07713	DECA_DROME	Protein decapentaplegic	11136981	Dpp gradient formation in the Drosophila wing imaginal disc.

P40092	SPI1_YEAST	Uncharacterized cell wall protein SPI1	9613572	Screening for glycosylphosphatidylinositol (GPI)-dependent cell wall proteins in Saccharomyces cerevisiae.

Q9C1X5	YKW2_SCHPO	Uncharacterized oxidoreductase P32A8.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P07741	APT_HUMAN	Adenine phosphoribosyltransferase	3531209	Human adenine phosphoribosyltransferase. Complete amino acid sequence of the erythrocyte enzyme.

Q71A38	PHLP2_DICDI	Phosducin-like protein 2	14517243	Phosducin-like proteins in Dictyostelium discoideum: implications for the phosducin family of proteins.

Q13153	PAK1_HUMAN	Serine/threonine-protein kinase PAK 1	8805275	Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway.

P45976	FIP1_YEAST	Pre-mRNA polyadenylation factor FIP1	11238938	Fip1 regulates the activity of Poly(A) polymerase through multiple interactions.

Q5RKL5	STEA3_RAT	Metalloreductase STEAP3	10969787	Growth inhibition of prostate cancer by an adenovirus expressing a novel tumor suppressor gene, pHyde.

O70377	SNP23_RAT	Synaptosomal-associated protein 23	14993220	Identification of SNAREs involved in synaptotagmin VII-regulated lysosomal exocytosis.

O43930	PRKY_HUMAN	Serine/threonine-protein kinase PRKY	9154127	FISH localization of the human Y-homologue of protein kinase PRKX to Yp11.2 and two pseudogenes to 15q26 and Xq12->13.

Q54NE6	PGAM_DICDI	Probable phosphoglycerate mutase	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P63170	DYL1_RAT	Dynein light chain 1, cytoplasmic	8864115	PIN: an associated protein inhibitor of neuronal nitric oxide synthase.

Q9UI09	NDUAC_HUMAN	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12	10830904	Characterization of the human complex I NDUFB7 and 17.2-kDa cDNAs and mutational analysis of 19 genes of the HP fraction in complex I- deficient-patients.

O60486	PLXC1_HUMAN	Plexin-C1	9586637	A poxvirus-encoded semaphorin induces cytokine production from monocytes and binds to a novel cellular semaphorin receptor, VESPR.

P38255	RXT2_YEAST	Transcriptional regulatory protein RXT2	16286008	Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex.

Q9VQG2	APH1_DROME	Gamma-secretase subunit Aph-1	12660785	The role of presenilin cofactors in the gamma-secretase complex.

Q9SI37	WRKY1_ARATH	WRKY transcription factor 1	8972846	Characterization of a zinc-dependent transcriptional activator from Arabidopsis.

P47027	DPB11_YEAST	DNA replication regulator DPB11	10097122	DRC1, DNA replication and checkpoint protein 1, functions with DPB11 to control DNA replication and the S-phase checkpoint in Saccharomyces cerevisiae.

P76193	YNHG_ECOLI	Probable L,D-transpeptidase YnhG	18456808	Identification of the L,D-transpeptidases for peptidoglycan cross- linking in Escherichia coli.

Q9FUZ2	DEF1B_ARATH	Peptide deformylase 1B, chloroplastic	18412546	Insights into the substrate specificity of plant peptide deformylase, an essential enzyme with potential for the development of novel biotechnology applications in agriculture.

Q76NU1	VATB_DICDI	V-type proton ATPase subunit B	16445684	Function and mechanism of action of Dictyostelium Nramp1 (Slc11a1) in bacterial infection.

O14189	PP2C5_SCHPO	Protein phosphatase 2C homolog C10F6.17c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9M2Y8	1A19_ARATH	1-aminocyclopropane-1-carboxylate synthase 9	12968022	Biochemical diversity among the 1-amino-cyclopropane-1-carboxylate synthase isozymes encoded by the Arabidopsis gene family.

Q09426	CGT_RAT	2-hydroxyacylsphingosine 1-beta-galactosyltransferase	7521399	Isolation, characterization, and expression of cDNA clones that encode rat UDP-galactose: ceramide galactosyltransferase.

Q12291	YL063_YEAST	Uncharacterized protein YLR063W	14562095	Global analysis of protein localization in budding yeast.

P08590	MYL3_HUMAN	Myosin light chain 3	8673105	Mutations in either the essential or regulatory light chains of myosin are associated with a rare myopathy in human heart and skeletal muscle.

P05549	AP2A_HUMAN	Transcription factor AP-2-alpha	8321221	An alternatively spliced mRNA from the AP-2 gene encodes a negative regulator of transcriptional activation by AP-2.

P40535	ACA2_YEAST	ATF/CREB activator 2	10825197	Aca1 and Aca2, ATF/CREB activators in Saccharomyces cerevisiae, are important for carbon source utilization but not the response to stress.

Q8NG31	CASC5_HUMAN	Protein CASC5	10980622	AF15q14, a novel partner gene fused to the MLL gene in an acute myeloid leukaemia with a t(11;15)(q23;q14).

Q8N114	SHSA5_HUMAN	Protein shisa-5	12761501	Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.

Q8IUX8	EGFL6_HUMAN	Epidermal growth factor-like protein 6	10610727	Cloning of a novel epidermal growth factor repeat containing gene EGFL6: expressed in tumor and fetal tissues.

O43759	SNG1_HUMAN	Synaptogyrin-1	9760194	Characterization of the human synaptogyrin gene family.

Q9NZM1	MYOF_HUMAN	Myoferlin	11959863	Calcium-sensitive phospholipid binding properties of normal and mutant ferlin C2 domains.

Q16635	TAZ_HUMAN	Tafazzin	19164547	Role of calcium-independent phospholipase A2 in the pathogenesis of Barth syndrome.

P70096	KIF2C_CRIGR	Kinesin-like protein KIF2C	19001124	A kinesin-13 mutant catalytically depolymerizes microtubules in ADP.

Q007T0	DHSB_PIG	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial	15989954	Crystal structure of mitochondrial respiratory membrane protein complex II.

O15304	SIVA_HUMAN	Apoptosis regulatory protein Siva	14739602	The Siva-1 putative amphipathic helical region (SAH) is sufficient to bind to BCL-XL and sensitize cells to UV radiation induced apoptosis.

Q9FLP6	SUMO2_ARATH	Small ubiquitin-related modifier 2	12482876	The small ubiquitin-like modifier (SUMO) protein modification system in Arabidopsis. Accumulation of SUMO1 and -2 conjugates is increased by stress.

P12961	7B2_MOUSE	Neuroendocrine protein 7B2	9348280	Mechanism of the facilitation of PC2 maturation by 7B2: involvement in ProPC2 transport and activation but not folding.

Q62839	GOGA2_RAT	Golgin subfamily A member 2	8557739	Characterization of a cis-Golgi matrix protein, GM130.

P14137	CP11A_RAT	Cholesterol side-chain cleavage enzyme, mitochondrial	2176216	Rat cholesterol side-chain cleavage cytochrome P-450 (P-450scc) gene. Structure and regulation by cAMP in vitro.

Q9H3D4	P63_HUMAN	Tumor protein 63	12446784	Complex transcriptional effects of p63 isoforms: identification of novel activation and repression domains.

P36104	SWD2_YEAST	COMPASS component SWD2	11742990	The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4.

Q9ES03	TBX20_MOUSE	T-box transcription factor TBX20	11118890	Cloning and expression analysis of the mouse T-box gene tbx20.

Q8S8L9	Y2245_ARATH	Uncharacterized TPR repeat-containing protein At2g32450	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P35396	PPARD_MOUSE	Peroxisome proliferator-activated receptor delta	8041794	Differential expression and activation of a family of murine peroxisome proliferator-activated receptors.

Q94CK4	ANXD8_ARATH	Annexin D8	16531057	Expression profiling of the Arabidopsis annexin gene family during germination, de-etiolation and abiotic stress.

Q8WZA1	PMGT1_HUMAN	Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1	11742540	Cloning and expression of a novel UDP-GlcNAc:alpha-D-mannoside beta- 1,2-N-acetylglucosaminyltransferase homologous to UDP-GlcNAc:alpha-3- D-mannoside beta-1,2-N-acetylglucosaminyltransferase I.

Q9UHA4	MPKS1_HUMAN	Mitogen-activated protein kinase scaffold protein 1	15016825	The structure of the MAPK scaffold, MP1, bound to its partner, p14. A complex with a critical role in endosomal MAP kinase signaling.

P77335	HLYE_ECOLI	Hemolysin E, chromosomal	10027972	Analysis of the SlyA-controlled expression, subcellular localization and pore-forming activity of a 34 kDa haemolysin (ClyA) from Escherichia coli K-12.

P21673	SAT1_HUMAN	Diamine acetyltransferase 1	1985966	Isolation and characterization of a cDNA clone that codes for human spermidine/spermine N1-acetyltransferase.

Q9FGN8	DYAD_ARATH	Protein DYAD	12783800	The meiotic protein SWI1 is required for axial element formation and recombination initiation in Arabidopsis.

O75530	EED_HUMAN	Polycomb protein EED	9584199	Characterization of interactions between the mammalian polycomb-group proteins Enx1/EZH2 and EED suggests the existence of different mammalian polycomb-group protein complexes.

Q9QY93	DCTP1_MOUSE	dCTP pyrophosphatase 1	17320107	Crystal structure of RS21-C6, involved in nucleoside triphosphate pyrophosphohydrolysis.

Q12000	TMA46_YEAST	Translation machinery-associated protein 46	16702403	Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes.

P08246	ELNE_HUMAN	Neutrophil elastase	15140022	Human leukocyte elastase and cathepsin G are specific inhibitors of C5a-dependent neutrophil enzyme release and chemotaxis.

P22362	CCL1_HUMAN	C-C motif chemokine 1	2212659	Sequence and chromosomal location of the I-309 gene. Relationship to genes encoding a family of inflammatory cytokines.

P42837	FIG4_YEAST	Polyphosphoinositide phosphatase	14528018	Vacuole size control: regulation of PtdIns(3,5)P2 levels by the vacuole-associated Vac14-Fig4 complex, a PtdIns(3,5)P2-specific phosphatase.

Q8MKW7	RNZ_DROME	Ribonuclease Z, mitochondrial	14715923	Drosophila RNase Z processes mitochondrial and nuclear pre-tRNA 3' ends in vivo.

Q5T4F7	SFRP5_HUMAN	Secreted frizzled-related protein 5	9391078	SARPs: a family of secreted apoptosis-related proteins.

Q7TQ33	RGMB_MOUSE	RGM domain family member B	14985445	DRAGON: a member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties.

P51020	HOA_ECOLI	4-hydroxy-2-oxovalerate aldolase	16782065	Coupled expression of MhpE aldolase and MhpF dehydrogenase in Escherichia coli.

P17886	CRN_DROME	Protein crooked neck	12163015	Drosophila crooked-neck protein co-fractionates in a multiprotein complex with splicing factors.

P48181	ACH2_CAEEL	Acetylcholine receptor subunit beta-type unc-29	9221782	Caenorhabditis elegans levamisole resistance genes lev-1, unc-29, and unc-38 encode functional nicotinic acetylcholine receptor subunits.

Q96LD8	SENP8_HUMAN	Sentrin-specific protease 8	15567417	Structure of a complex between Nedd8 and the Ulp/Senp protease family member Den1.

Q9NZJ7	MTCH1_HUMAN	Mitochondrial carrier homolog 1	12377771	The novel presenilin-1-associated protein is a proapoptotic mitochondrial protein.

P85060	PA2A2_ACASS	Phospholipase A2, acanmyotoxin-2	16242671	Isolation and characterisation of acanmyotoxin-2 and acanmyotoxin-3, myotoxins from the venom of the death adder Acanthophis sp. Seram.

P53919	NAF1_YEAST	H/ACA ribonucleoprotein complex non-core subunit NAF1	12242285	Naf1p, an essential nucleoplasmic factor specifically required for accumulation of box H/ACA small nucleolar RNPs.

Q3E7B2	YJ062_YEAST	Mitochondrial membrane protein YJL062W-A	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

O95218	ZRAB2_HUMAN	Zinc finger Ran-binding domain-containing protein 2	16982639	XE7: a novel splicing factor that interacts with ASF/SF2 and ZNF265.

Q9VS48	SLX4_DROME	Structure-specific endonuclease subunit SLX4	19595722	Drosophila MUS312 and the vertebrate ortholog BTBD12 interact with DNA structure-specific endonucleases in DNA repair and recombination.

O00295	TULP2_HUMAN	Tubby-related protein 2	9096357	Molecular characterization of TUB, TULP1, and TULP2, members of the novel tubby gene family and their possible relation to ocular diseases.

O43012	DCTD_SCHPO	Deoxycytidylate deaminase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NZQ9	TMOD4_HUMAN	Tropomodulin-4	10662549	Sequencing, expression analysis, and mapping of three unique human tropomodulin genes and their mouse orthologs.

O35129	PHB2_MOUSE	Prohibitin-2	12878603	Truncated estrogen receptor product-1 stimulates estrogen receptor alpha transcriptional activity by titration of repressor proteins.

Q05471	SWR1_YEAST	Helicase SWR1	14690608	A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1.

P68104	EF1A1_HUMAN	Elongation factor 1-alpha 1	2564392	Isolation and characterization of the human chromosomal gene for polypeptide chain elongation factor-1 alpha.

P49333	ETR1_ARATH	Ethylene receptor 1	8525372	Ethylene-binding sites generated in yeast expressing the Arabidopsis ETR1 gene.

O43593	HAIR_HUMAN	Protein hairless	9445480	Alopecia universalis associated with a mutation in the human hairless gene.

P40063	RT105_YEAST	Regulator of Ty1 transposition protein 105	11779788	Multiple regulators of Ty1 transposition in Saccharomyces cerevisiae have conserved roles in genome maintenance.

Q91YE5	BAZ2A_MOUSE	Bromodomain adjacent to zinc finger domain protein 2A	19578370	Reversible acetylation of the chromatin remodelling complex NoRC is required for non-coding RNA-dependent silencing.

Q03940	RUVB1_YEAST	RuvB-like protein 1	11278922	Rvb1p and Rvb2p are essential components of a chromatin remodeling complex that regulates transcription of over 5% of yeast genes.

Q9Y7R3	CND2_SCHPO	Condensin complex subunit 2	10485849	Fission yeast condensin complex: essential roles of non-SMC subunits for condensation and Cdc2 phosphorylation of Cut3/SMC4.

P07202	PERT_HUMAN	Thyroid peroxidase	3475693	Human thyroid peroxidase: complete cDNA and protein sequence, chromosome mapping, and identification of two alternately spliced mRNAs.

Q86WV5	TEN1L_HUMAN	CST complex subunit TEN1	19854130	RPA-like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathway.

Q9PRJ8	FXD5A_XENLA	Forkhead box protein D5-A	15656969	Of fox and frogs: fox (fork head/winged helix) transcription factors in Xenopus development.

P39990	SNU13_YEAST	13 kDa ribonucleoprotein-associated protein	10449419	Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6.U5] tri-snRNP.

Q10120	LIN52_CAEEL	Protein lin-52	12750327	New genes that interact with lin-35 Rb to negatively regulate the let-60 ras pathway in Caenorhabditis elegans.

Q98SN7	WNT2B_CHICK	Protein Wnt-2b	11290326	WNT signals control FGF-dependent limb initiation and AER induction in the chick embryo.

Q9JKT5	TR105_RAT	Taste receptor type 2 member 105	10761934	A novel family of mammalian taste receptors.

Q9JJR7	ASCL3_MOUSE	Achaete-scute homolog 3	11784080	Sgn1, a basic helix-loop-helix transcription factor delineates the salivary gland duct cell lineage in mice.

P11117	PPAL_HUMAN	Lysosomal acid phosphatase	2776754	Structure of the human lysosomal acid phosphatase gene.

P40847	SAP1_SCHPO	Switch-activating protein 1	8114737	Sap1, a protein that binds to sequences required for mating-type switching, is essential for viability in Schizosaccharomyces pombe.

P23873	HIPB_ECOLI	HTH-type transcriptional regulator hipB	8021189	Autoregulation of hip, an operon that affects lethality due to inhibition of peptidoglycan or DNA synthesis.

Q96BD8	SKA1_HUMAN	Spindle and kinetochore-associated protein 1	17093495	Timely anaphase onset requires a novel spindle and kinetochore complex comprising Ska1 and Ska2.

Q42560	ACO1_ARATH	Aconitate hydratase 1	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P57796	CABP4_HUMAN	Calcium-binding protein 4	15452577	Essential role of Ca2+-binding protein 4, a Cav1.4 channel regulator, in photoreceptor synaptic function.

Q66K74	MAP1S_HUMAN	Microtubule-associated protein 1S	15907802	Putative tumor suppressor RASSF1 interactive protein and cell death inducer C19ORF5 is a DNA binding protein.

P36141	FMP46_YEAST	Putative redox protein FMP46, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

P35609	ACTN2_HUMAN	Alpha-actinin-2	1339456	Cloning and characterization of two human skeletal muscle alpha- actinin genes located on chromosomes 1 and 11.

Q3B725	ZBT24_RAT	Zinc finger and BTB domain-containing protein 24	15526281	Bone morphogenetic protein-2 induces expression of murine zinc finger transcription factor ZNF450.

Q06344	ESF1_YEAST	Pre-rRNA-processing protein ESF1	15056729	ESF1 is required for 18S rRNA synthesis in Saccharomyces cerevisiae.

Q9VAC8	SAS6_DROME	Spindle assembly abnormal protein 6 homolog	17412918	Genes required for mitotic spindle assembly in Drosophila S2 cells.

P31214	S5A2_RAT	3-oxo-5-alpha-steroid 4-dehydrogenase 2	1527072	Tissue distribution and kinetic characteristics of rat steroid 5 alpha-reductase isozymes. Evidence for distinct physiological functions.

Q9XIE2	AB36G_ARATH	ABC transporter G family member 36	19095898	Glucosinolate metabolites required for an Arabidopsis innate immune response.

Q12069	PUS9_YEAST	tRNA pseudouridine synthase 9, mitochondrial	15466869	Pseudouridylation at position 32 of mitochondrial and cytoplasmic tRNAs requires two distinct enzymes in Saccharomyces cerevisiae.

O74847	YCYB_SCHPO	UPF0041 protein C1235.11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Y802	LSD1_SCHPO	Lysine-specific histone demethylase 1	16990277	Fission yeast homologs of human histone H3 lysine 4 demethylase regulate a common set of genes with diverse functions.

Q03280	TOM1_YEAST	E3 ubiquitin-protein ligase TOM1	11238398	Genes encoding ribosomal proteins Rps0A/B of Saccharomyces cerevisiae interact with TOM1 mutants defective in ribosome synthesis.

Q06904	SASA_SYNE7	Adaptive-response sensory-kinase sasA	10786837	A kaiC-interacting sensory histidine kinase, SasA, necessary to sustain robust circadian oscillation in cyanobacteria.

Q84LH3	WEX_ARATH	Werner Syndrome-like exonuclease	12937173	Biochemical characterization of an exonuclease from Arabidopsis thaliana reveals similarities to the DNA exonuclease of the human Werner syndrome protein.

Q8BGV3	TACD2_MOUSE	Tumor-associated calcium signal transducer 2	9462726	Cloning of the murine TROP2 gene: conservation of a PIP2-binding sequence in the cytoplasmic domain of TROP-2.

Q06188	YL455_YEAST	PWWP domain-containing protein YLR455W	14562095	Global analysis of protein localization in budding yeast.

P83520	FER_DATAR	Ferredoxin	7765623	Amino acid sequence of ferredoxin from Datura arborea.

O88958	GNPI1_MOUSE	Glucosamine-6-phosphate isomerase 1	10481053	Characterization of testicular mouse glucosamine 6-phosphate deaminase (GNPDA).

Q56134	SIPB_SALTI	Cell invasion protein sipB	10051653	The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1.

Q62947	ZEB1_RAT	Zinc finger E-box-binding homeobox 1	8769566	Alternative splicing gives rise to two isoforms of Zfhep, a zinc finger/homeodomain protein that binds T3-response elements.

P85874	WPMM2_POLMJ	Mastoparan-like peptide PMM2	17559065	Identification of three novel peptides isolated from the venom of the neotropical social wasp Polistes major major.

P70056	FOXH1_XENLA	Forkhead box protein H1	10691736	Homeodomain and winged-helix transcription factors recruit activated Smads to distinct promoter elements via a common Smad interaction motif.

P24100	CDKA1_ARATH	Cyclin-dependent kinase A-1	9276444	The Arabidopsis Cks1At protein binds the cyclin-dependent kinases Cdc2aAt and Cdc2bAt.

O95232	LC7L3_HUMAN	Luc7-like protein 3	10631324	CROP/Luc7A, a novel serine/arginine-rich nuclear protein, isolated from cisplatin-resistant cell line.

Q16254	E2F4_HUMAN	Transcription factor E2F4	11418595	E2F transcriptional activation requires TRRAP and GCN5 cofactors.

P34931	HS71L_HUMAN	Heat shock 70 kDa protein 1-like	9685725	Genomic structure of the spermatid-specific HSP70 homolog gene located in the class III region of the major histocompatibility complex of mouse and man.

P38200	SHE1_YEAST	Mitotic spindle-associated protein SHE1	14562095	Global analysis of protein localization in budding yeast.

Q05123	ARP9_YEAST	Actin-like protein ARP9	12805231	The nuclear actin-related proteins Arp7 and Arp9: a dimeric module that cooperates with architectural proteins for chromatin remodeling.

Q16514	TAF12_HUMAN	Transcription initiation factor TFIID subunit 12	11564863	Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage- binding factors in vivo.

O60260	PRKN2_HUMAN	E3 ubiquitin-protein ligase parkin	18541373	Parkin is ubiquitinated by Nrdp1 and abrogates Nrdp1-induced oxidative stress.

P38025	PUR7_ARATH	Phosphoribosylaminoimidazole-succinocarboxamide synthase, chloroplastic	8938402	De novo purine synthesis in Arabidopsis thaliana. II. The PUR7 gene encoding 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole synthetase is expressed in rapidly dividing tissues.

P34278	KNL1_CAEEL	Kinetochore null protein 1	15371340	A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension.

Q12303	YPS3_YEAST	Aspartic proteinase yapsin-3	11016834	Up-regulation of genes encoding glycosylphosphatidylinositol (GPI)- attached proteins in response to cell wall damage caused by disruption of FKS1 in Saccharomyces cerevisiae.

Q96252	ATP4_ARATH	ATP synthase subunit delta', mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q00977	CXB2_MOUSE	Gap junction beta-2 protein	19864490	Consortin, a trans-Golgi network cargo receptor for the plasma membrane targeting and recycling of connexins.

O48814	BIK1_ARATH	Serine/threonine-protein kinase BIK1	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q9WUN2	TBK1_MOUSE	Serine/threonine-protein kinase TBK1	10581243	NF-kB activation by a signaling complex containing TRAF2, TANK, and TBK1, a novel IKK-related kinase.

Q6ZQW0	I23O2_HUMAN	Indoleamine 2,3-dioxygenase 2	17671174	Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan.

Q12473	FRE6_YEAST	Ferric reductase transmembrane component 6	17681937	The metalloreductase Fre6p in Fe-efflux from the yeast vacuole.

P11766	ADHX_HUMAN	Alcohol dehydrogenase class-3	8460164	Mutation of Arg-115 of human class III alcohol dehydrogenase: a binding site required for formaldehyde dehydrogenase activity and fatty acid activation.

P16989	DBPA_HUMAN	DNA-binding protein A	8710501	Cold shock domain proteins repress transcription from the GM-CSF promoter.

P60484	PTEN_HUMAN	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	10468583	The tumor-suppressor activity of PTEN is regulated by its carboxyl- terminal region.

P32755	HPPD_RAT	4-hydroxyphenylpyruvate dioxygenase	8814303	The C-terminal of rat 4-hydroxyphenylpyruvate dioxygenase is indispensable for enzyme activity.

P11911	CD79A_MOUSE	B-cell antigen receptor complex-associated protein alpha chain	12097390	B cell progenitors are arrested in maturation but have intact VDJ recombination in the absence of Ig-alpha and Ig-beta.

P76491	YFBR_ECOLI	5'-nucleotidase yfbR	15489502	General enzymatic screens identify three new nucleotidases in Escherichia coli. Biochemical characterization of SurE, YfbR, and YjjG.

Q9SCY0	PGMP_ARATH	Phosphoglucomutase, chloroplastic	10954083	Molecular characterisation of a new mutant allele of the plastid phosphoglucomutase in Arabidopsis, and complementation of the mutant with the wild-type cDNA.

Q9M224	ADLO2_ARATH	Protein ARABIDILLO 2	16434475	Armadillo-related proteins promote lateral root development in Arabidopsis.

P03372	ESR1_HUMAN	Estrogen receptor	16603732	Identification of the MLL2 complex as a coactivator for estrogen receptor alpha.

O88898	P63_MOUSE	Tumor protein 63	9774969	p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities.

P31688	TPS2_YEAST	Trehalose-phosphatase	9837904	Composition and functional analysis of the Saccharomyces cerevisiae trehalose synthase complex.

Q9QX73	ARHG9_RAT	Rho guanine nucleotide exchange factor 9	10607391	Collybistin, a newly identified brain-specific GEF, induces submembrane clustering of gephyrin.

P15624	SYFB_YEAST	Phenylalanyl-tRNA synthetase beta chain	3049607	Structure and expression of the genes encoding the alpha and beta subunits of yeast phenylalanyl-tRNA synthetase.

P12982	PP12_DROME	Serine/threonine-protein phosphatase alpha-2 isoform	1330679	Protein phosphorylation is involved in the regulation of chromatin condensation during interphase.

Q61072	ADAM9_MOUSE	Disintegrin and metalloproteinase domain-containing protein 9	8647900	MDC9, a widely expressed cellular disintegrin containing cytoplasmic SH3 ligand domains.

Q7K4M4	TEF_DROME	Protein teflon	16816414	Molecular characterization of teflon, a gene required for meiotic autosome segregation in male Drosophila melanogaster.

Q6ZWR6	SYNE1_MOUSE	Nesprin-1	10878022	Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction.

Q60598	SRC8_MOUSE	Src substrate cortactin	12913069	Fgd1, the Cdc42 GEF responsible for faciogenital dysplasia, directly interacts with cortactin and mAbp1 to modulate cell shape.

P20489	FCERA_MOUSE	High affinity immunoglobulin epsilon receptor subunit alpha	2527850	Complete structure of the mouse mast cell receptor for IgE (Fc epsilon RI) and surface expression of chimeric receptors (rat-mouse- human) on transfected cells.

Q15113	PCOC1_HUMAN	Procollagen C-endopeptidase enhancer 1	7523404	Type I procollagen COOH-terminal proteinase enhancer protein: identification, primary structure, and chromosomal localization of the cognate human gene (PCOLCE).

Q13875	MOBP_HUMAN	Myelin-associated oligodendrocyte basic protein	7989345	Cloning and expression of myelin-associated oligodendrocytic basic protein. A novel basic protein constituting the central nervous system myelin.

Q92630	DYRK2_HUMAN	Dual specificity tyrosine-phosphorylation-regulated kinase 2	17349958	DYRK2 is targeted to the nucleus and controls p53 via Ser46 phosphorylation in the apoptotic response to DNA damage.

Q8NI77	KI18A_HUMAN	Kinesin-like protein KIF18A	18680169	New insights on cellular distribution, microtubule interactions and post-translational modifications of MS-KIF18A.

P53136	NSA1_YEAST	Ribosome biogenesis protein NSA1	11583614	Composition and functional characterization of yeast 66S ribosome assembly intermediates.

Q8CF93	GLT13_MOUSE	Polypeptide N-acetylgalactosaminyltransferase 13	12407114	Cloning and characterization of a new human UDP-N-acetyl-alpha-D- galactosamine:polypeptide N-acetylgalactosaminyltransferase, designated pp-GalNAc-T13, that is specifically expressed in neurons and synthesizes GalNAc alpha-serine/threonine antigen.

Q9V629	DOM3Z_DROME	Protein Dom3Z	17363252	Cutoff and aubergine mutations result in retrotransposon upregulation and checkpoint activation in Drosophila.

Q86LR2	HLYS1_CHLVR	Hydralysin-1	12885226	Hydralysin, a novel animal group-selective paralytic and cytolytic protein from a noncnidocystic origin in hydra.

P84806	CRV25_NAJHH	Cysteine-rich venom protein 25	15670767	Cobra venom contains a pool of cysteine-rich secretory proteins.

P05986	KAPC_YEAST	cAMP-dependent protein kinase type 3	3036373	Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase.

Q9P1P4	TAAR3_HUMAN	Putative trace amine-associated receptor 3	10684976	Cloning and characterization of additional members of the G protein- coupled receptor family.

Q93W54	ICMTB_ARATH	Protein-S-isoprenylcysteine O-methyltransferase B	18641086	Functional analysis of Arabidopsis postprenylation CaaX processing enzymes and their function in subcellular protein targeting.

Q01574	ACS1_YEAST	Acetyl-coenzyme A synthetase 1	16857587	Nucleocytosolic acetyl-coenzyme a synthetase is required for histone acetylation and global transcription.

P48582	BRO1_YEAST	Vacuolar-sorting protein BRO1	8649366	BRO1, a novel gene that interacts with components of the Pkc1p- mitogen-activated protein kinase pathway in Saccharomyces cerevisiae.

O43240	KLK10_HUMAN	Kallikrein-10	8764136	Identification of a novel serine protease-like gene, the expression of which is down-regulated during breast cancer progression.

P29474	NOS3_HUMAN	Nitric oxide synthase, endothelial	12446846	NOSTRIN: a protein modulating nitric oxide release and subcellular distribution of endothelial nitric oxide synthase.

Q9EPX5	FXL12_MOUSE	F-box/LRR-repeat protein 12	10531037	A family of mammalian F-box proteins.

Q9VNA5	PSB4_DROME	Proteasome subunit beta type-4	17412918	Genes required for mitotic spindle assembly in Drosophila S2 cells.

Q00987	MDM2_HUMAN	E3 ubiquitin-protein ligase Mdm2	16474402	Molecular recognition of p53 and MDM2 by USP7/HAUSP.

Q9FXI5	IQD32_ARATH	Protein IQ-DOMAIN 32	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

P36673	TRER_ECOLI	HTH-type transcriptional regulator treR	9148912	Characterization of TreR, the major regulator of the Escherichia coli trehalose system.

Q50L39	BI52A_XENLA	Baculoviral IAP repeat-containing protein 5.2-A	15853809	Apoptosis-inhibiting activities of BIR family proteins in Xenopus egg extracts.

Q12362	RIB2_YEAST	Bifunctional protein RIB2	15466869	Pseudouridylation at position 32 of mitochondrial and cytoplasmic tRNAs requires two distinct enzymes in Saccharomyces cerevisiae.

Q61574	FOXS1_MOUSE	Forkhead box protein S1	18288644	Importance of forkhead transcription factor Fkhl18 for development of testicular vasculature.

P09088	MEC3_CAEEL	Mechanosensory protein 3	1361171	Regulation of the mec-3 gene by the C.elegans homeoproteins UNC-86 and MEC-3.

P0ABZ6	SURA_ECOLI	Chaperone surA	11226178	The SurA periplasmic PPIase lacking its parvulin domains functions in vivo and has chaperone activity.

P50294	ARY1_MOUSE	Arylamine N-acetyltransferase 1	7545952	Arylamine N-acetyltransferase in Balb/c mice: identification of a novel mouse isoenzyme by cloning and expression in vitro.

Q63113	FXYD4_RAT	FXYD domain-containing ion transport regulator 4	7597086	A corticosteroid-induced gene expressing an 'IsK-like' K+ channel activity in Xenopus oocytes.

P40545	HIS4_YEAST	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase	9332345	Paralogous histidine biosynthetic genes: evolutionary analysis of the Saccharomyces cerevisiae HIS6 and HIS7 genes.

Q55G87	CANB1_DICDI	Calcineurin subunit B type 1	16512895	Aberrant stalk development and breakdown of tip dominance in Dictyostelium cell lines with RNAi-silenced expression of calcineurin B.

P06844	SPT3_YEAST	Protein SPT3	11485989	The S. cerevisiae SAGA complex functions in vivo as a coactivator for transcriptional activation by Gal4.

Q12382	DGK1_YEAST	CTP-dependent diacylglycerol kinase 1	11481671	Multicopy suppressors of the sly1 temperature-sensitive mutation in the ER-Golgi vesicular transport in Saccharomyces cerevisiae.

Q14141	SEPT6_HUMAN	Septin-6	17803907	Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7.

Q9UQL6	HDAC5_HUMAN	Histone deacetylase 5	11081517	Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation.

P62081	RS7_HUMAN	40S ribosomal protein S7	11823430	Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains.

P27654	TIP1_YEAST	Temperature shock-inducible protein 1	10216230	Structure of the glucan-binding sugar chain of Tip1p, a cell wall protein of Saccharomyces cerevisiae.

O94808	GFPT2_HUMAN	Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 2	10198162	cDNA cloning and mapping of a novel subtype of glutamine:fructose-6- phosphate amidotransferase (GFAT2) in human and mouse.

Q80X90	FLNB_MOUSE	Filamin-B	11807098	Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin (beta) subunits.

Q9LIB6	COBL8_ARATH	COBRA-like protein 8	12376623	The COBRA family of putative GPI-anchored proteins in Arabidopsis. A new fellowship in expansion.

Q14242	SELPL_HUMAN	P-selectin glycoprotein ligand 1	18196517	SLIC-1/sorting nexin 20: a novel sorting nexin that directs subcellular distribution of PSGL-1.

O34680	YDIP_BACSU	Probable BsuMI modification methylase subunit ydiP	11751814	Molecular organization of intrinsic restriction and modification genes BsuM of Bacillus subtilis Marburg.

Q8C4Q6	AIDA_MOUSE	Axin interactor, dorsalization-associated protein	17681137	A beta-catenin-independent dorsalization pathway activated by Axin/JNK signaling and antagonized by aida.

Q9M021	LRKA1_ARATH	Lectin-domain containing receptor kinase A4.1	18987212	The Arabidopsis a4 subfamily of lectin receptor kinases negatively regulates abscisic acid response in seed germination.

Q8HWS3	RFX6_HUMAN	DNA-binding protein RFX6	20148032	Rfx6 directs islet formation and insulin production in mice and humans.

P36106	BYE1_YEAST	Transcription factor BYE1	14704159	The ESS1 prolyl isomerase and its suppressor BYE1 interact with RNA pol II to inhibit transcription elongation in Saccharomyces cerevisiae.

Q54HG2	CTXA_DICDI	Cortexillin-1	8752217	Cortexillins, major determinants of cell shape and size, are actin- bundling proteins with a parallel coiled-coil tail.

P14678	RSMB_HUMAN	Small nuclear ribonucleoprotein-associated proteins B and B'	2531083	Cloned human snRNP proteins B and B' differ only in their carboxy- terminal part.

P01591	IGJ_HUMAN	Immunoglobulin J chain	2984306	Human J chain gene. Structure and expression in B lymphoid cells.

Q9U3C8	DCN1_CAEEL	Defective in cullin neddylation protein 1	15988528	The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae.

Q969N2	PIGT_HUMAN	GPI transamidase component PIG-T	11483512	PIG-S and PIG-T, essential for GPI anchor attachment to proteins, form a complex with GAA1 and GPI8.

Q09XV5	CHD8_MOUSE	Chromodomain-helicase-DNA-binding protein 8	15367660	Early embryonic death in mice lacking the beta-catenin-binding protein Duplin.

Q52T38	ZDH22_ARATH	S-acyltransferase TIP1	8022944	Pollen tube and root-hair tip growth is disrupted in a mutant of Arabidopsis thaliana.

P25342	CDC10_YEAST	Cell division control protein 10	8791410	The septins: roles in cytokinesis and other processes.

P40341	YTA12_YEAST	Mitochondrial respiratory chain complexes assembly protein YTA12	7929327	A new member of a family of ATPases is essential for assembly of mitochondrial respiratory chain and ATP synthetase complexes in Saccharomyces cerevisiae.

O13612	NEP2_SCHPO	NEDD8-specific protease 2	15769255	Nep1, a Schizosaccharomyces pombe deneddylating enzyme.

P38325	OM14_YEAST	Mitochondrial outer membrane protein OM14	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

O00410	IPO5_HUMAN	Importin-5	9271386	Ran-binding protein 5 (RanBP5) is related to the nuclear transport factor importin-beta but interacts differently with RanBP1.

Q09669	ADH4_SCHPO	Alcohol dehydrogenase 4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P25311	ZA2G_HUMAN	Zinc-alpha-2-glycoprotein	10206894	Crystal structure of human ZAG, a fat-depleting factor related to MHC molecules.

P11215	ITAM_HUMAN	Integrin alpha-M	2563162	cDNA sequence for the alpha M subunit of the human neutrophil adherence receptor indicates homology to integrin alpha subunits.

Q13952	NFYC_HUMAN	Nuclear transcription factor Y subunit gamma	10446203	Cell cycle-dependent switch of up- and down-regulation of human hsp70 gene expression by interaction between c-Myc and CBF/NF-Y.

P47026	GWT1_YEAST	GPI-anchored wall transfer protein 1	16361252	Glycosylphosphatidylinositol-anchored proteins are required for the transport of detergent-resistant microdomain-associated membrane proteins Tat2p and Fur4p.

Q9Z2I6	SV2C_RAT	Synaptic vesicle glycoprotein 2C	9801366	SVOP, an evolutionarily conserved synaptic vesicle protein, suggests novel transport functions of synaptic vesicles.

P40855	PEX19_HUMAN	Peroxisomal biogenesis factor 19	10051604	Human PEX19: cDNA cloning by functional complementation, mutation analysis in a patient with Zellweger syndrome, and potential role in peroxisomal membrane assembly.

Q8CBD1	NRIP1_MOUSE	Nuclear receptor-interacting protein 1	10531331	Characterization of receptor-interacting protein 140 in retinoid receptor activities.

P13929	ENOB_HUMAN	Beta-enolase	8513787	Structural features of the human gene for muscle-specific enolase. Differential splicing in the 5'-untranslated sequence generates two forms of mRNA.

Q13867	BLMH_HUMAN	Bleomycin hydrolase	8639621	Human bleomycin hydrolase: molecular cloning, sequencing, functional expression, and enzymatic characterization.

Q9UUA6	DPP1_SCHPO	Probable diacylglycerol pyrophosphate phosphatase 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UUC7	CTU2_SCHPO	Cytoplasmic tRNA 2-thiolation protein 2	18391219	The conserved wobble uridine tRNA thiolase Ctu1-Ctu2 is required to maintain genome integrity.

Q9USN2	YCL3_SCHPO	UPF0652 protein C16A11.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P55084	ECHB_HUMAN	Trifunctional enzyme subunit beta, mitochondrial	8135828	Structural analysis of cDNAs for subunits of human mitochondrial fatty acid beta-oxidation trifunctional protein.

Q07533	CYK3_YEAST	Cytokinesis protein 3	10959846	Cyk3, a novel SH3-domain protein, affects cytokinesis in yeast.

P42345	MTOR_HUMAN	Serine/threonine-protein kinase mTOR	10089303	Refined structure of the FKBP12-rapamycin-FRB ternary complex at 2.2 A resolution.

P31545	YCDB_ECOLI	Peroxidase ycdB	16551627	YcdB from Escherichia coli reveals a novel class of Tat-dependently translocated hemoproteins.

P39014	MET30_YEAST	F-box protein MET30	14660673	The amino-terminal portion of the F-box protein Met30p mediates its nuclear import and assimilation into an SCF complex.

Q04900	MUC24_HUMAN	Sialomucin core protein 24	9763543	The sialomucin CD164 (MGC-24v) is an adhesive glycoprotein expressed by human hematopoietic progenitors and bone marrow stromal cells that serves as a potent negative regulator of hematopoiesis.

P79944	EOMES_XENLA	Eomesodermin	11585801	Determinants of T box protein specificity.

Q86VP1	TAXB1_HUMAN	Tax1-binding protein 1	14697242	Chromosome 13q12 encoded Rho GTPase activating protein suppresses growth of breast carcinoma cells, and yeast two-hybrid screen shows its interaction with several proteins.

Q02241	KIF23_HUMAN	Kinesin-like protein KIF23	15197175	Annexin 11 is required for midbody formation and completion of the terminal phase of cytokinesis.

Q06493	YLH47_YEAST	LETM1 domain-containing protein YLH47, mitochondrial	16476776	Mdm38 interacts with ribosomes and is a component of the mitochondrial protein export machinery.

P22760	AAAD_HUMAN	Arylacetamide deacetylase	8063807	Human liver arylacetamide deacetylase. Molecular cloning of a novel esterase involved in the metabolic activation of arylamine carcinogens with high sequence similarity to hormone-sensitive lipase.

P36629	U2AF2_SCHPO	Splicing factor U2AF 59 kDa subunit	12374752	Pre-spliceosome formation in S.pombe requires a stable complex of SF1-U2AF(59)-U2AF(23).

P31209	PABP_SCHPO	Polyadenylate-binding protein, cytoplasmic and nuclear	12062100	Cid13 is a cytoplasmic poly(A) polymerase that regulates ribonucleotide reductase mRNA.

P41800	MMM1_YEAST	Maintenance of mitochondrial morphology protein 1	11266455	Mmm1p, a mitochondrial outer membrane protein, is connected to mitochondrial DNA (mtDNA) nucleoids and required for mtDNA stability.

Q9NZB8	MOCS1_HUMAN	Molybdenum cofactor biosynthesis protein 1	16021469	Ten novel mutations in the molybdenum cofactor genes MOCS1 and MOCS2 and in vitro characterization of a MOCS2 mutation that abolishes the binding ability of molybdopterin synthase.

Q9UN72	PCDA7_HUMAN	Protocadherin alpha-7	10380929	A striking organization of a large family of human neural cadherin- like cell adhesion genes.

Q9Y4F1	FARP1_HUMAN	FERM, RhoGEF and pleckstrin domain-containing protein 1	9425278	Molecular cloning and characterization of CDEP, a novel human protein containing the ezrin-liks domain of the band 4.1 superfamily and the Dbl homology domain of rho guanine nucleotide exchange factors.

Q7Z9I3	YCP8_SCHPO	Uncharacterized oxidoreductase C663.08c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Y7L5	YGJ3_SCHPO	Uncharacterized protein C685.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9JIA1	LGI1_MOUSE	Leucine-rich glioma-inactivated protein 1	18974846	LGI1 and LGI4 bind to ADAM22, ADAM23 and ADAM11.

Q5TAX3	TUT4_HUMAN	Terminal uridylyltransferase 4	18172165	Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'.

P01374	TNFB_HUMAN	Lymphotoxin-alpha	6334807	Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumour necrosis activity.

P33225	TORA_ECOLI	Trimethylamine-N-oxide reductase 1	2512991	The inducible trimethylamine N-oxide reductase of Escherichia coli K12: its localization and inducers.

Q9LYG9	Y5208_ARATH	Uncharacterized protein At5g12080	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

P02686	MBP_HUMAN	Myelin basic protein	7504278	The human myelin basic protein gene is included within a 179-kilobase transcription unit: expression in the immune and central nervous systems.

O14459	RPB7_SCHPO	DNA-directed RNA polymerase II subunit rpb7	12907709	Rpb7 subunit of RNA polymerase II interacts with an RNA-binding protein involved in processing of transcripts.

P33307	CSE1_YEAST	Importin alpha re-exporter	9857050	Cse1p is required for export of Srp1p/importin-alpha from the nucleus in Saccharomyces cerevisiae.

P13351	CCNB2_XENLA	G2/mitotic-specific cyclin-B2	7622566	Members of the NAP/SET family of proteins interact specifically with B-type cyclins.

O60573	IF4E2_HUMAN	Eukaryotic translation initiation factor 4E type 2	17368478	Structures of the human eIF4E homologous protein, h4EHP, in its m7GTP-bound and unliganded forms.

Q54PX9	RS12_DICDI	40S ribosomal protein S12	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P30307	MPIP3_HUMAN	M-phase inducer phosphatase 3	11139144	Alternative splicing in the regulatory region of the human phosphatases CDC25A and CDC25C.

P28274	URA7_YEAST	CTP synthase 1	8075080	Purification and characterization of CTP synthetase, the product of the URA7 gene in Saccharomyces cerevisiae.

O08574	MESP2_MOUSE	Mesoderm posterior protein 2	15902259	The Mesp2 transcription factor establishes segmental borders by suppressing Notch activity.

P53738	TR112_YEAST	Multifunctional methyltransferase subunit TRM112	15899842	Trm11p and Trm112p are both required for the formation of 2- methylguanosine at position 10 in yeast tRNA.

Q8INK6	PGPLB_DROME	Peptidoglycan-recognition protein LB	12032070	The Toll and Imd pathways are the major regulators of the immune response in Drosophila.

P15882	CHIN_HUMAN	N-chimaerin	8336731	Alpha 2-chimerin, an SH2-containing GTPase-activating protein for the ras-related protein p21rac derived by alternate splicing of the human n-chimerin gene, is selectively expressed in brain regions and testes.

Q9Y7Y3	YGR4_SCHPO	Uncharacterized RNA-binding protein C365.04c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q5VVJ2	MYSM1_HUMAN	Histone H2A deubiquitinase MYSM1	18669648	A quantitative atlas of mitotic phosphorylation.

Q9U1M8	MYOI_DICDI	Myosin-I heavy chain	10574761	A class VII unconventional myosin is required for phagocytosis.

P32600	TOR2_YEAST	Serine/threonine-protein kinase TOR2	14593073	Receptor internalization in yeast requires the Tor2-Rho1 signaling pathway.

Q7Z6Z7	HUWE1_HUMAN	E3 ubiquitin-protein ligase HUWE1	15989956	ARF-BP1/Mule is a critical mediator of the ARF tumor suppressor.

Q9JHY3	WFD12_MOUSE	WAP four-disulfide core domain protein 12	12574366	Mouse SWAM1 and SWAM2 are antibacterial proteins composed of a single whey acidic protein motif.

Q9H936	GHC1_HUMAN	Mitochondrial glutamate carrier 1	11897791	Identification of the mitochondrial glutamate transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution of two human isoforms.

P39994	YEC0_YEAST	Putative 2-hydroxyacyl-CoA lyase	14562095	Global analysis of protein localization in budding yeast.

Q8H1Z0	WAX2_ARATH	Protein WAX2	16618929	Mapping the Arabidopsis organelle proteome.

P34925	RYK_HUMAN	Tyrosine-protein kinase RYK	8386829	Molecular cloning and chromosomal localisation of the human homologue of a receptor related to tyrosine kinases (RYK).

Q14508	WFDC2_HUMAN	WAP four-disulfide core domain protein 2	1686187	A major human epididymis-specific cDNA encodes a protein with sequence homology to extracellular proteinase inhibitors.

O13326	CYSD_SCHPO	O-acetylhomoserine (thiol)-lyase	11754480	Sulphur amino acid synthesis in Schizosaccharomyces pombe represents a specific variant of sulphur metabolism in fungi.

Q8W033	AL3I1_ARATH	Aldehyde dehydrogenase family 3 member I1, chloroplastic	11849595	Novel ABA- and dehydration-inducible aldehyde dehydrogenase genes isolated from the resurrection plant Craterostigma plantagineum and Arabidopsis thaliana.

Q7SYL3	SIAH2_DANRE	E3 ubiquitin-protein ligase Siah2	15055544	The RING domain of Siaz, the zebrafish homologue of Drosophila seven in absentia, is essential for cellular growth arrest.

Q80U96	XPO1_RAT	Exportin-1	11689633	Rat CRM1 is responsible for the poor activity of human T-cell leukemia virus type 1 Rex protein in rat cells.

Q9GRF8	EF1B_DICDI	Elongation factor 1-beta	11479029	Elongation factor 1beta is an actin-binding protein.

Q10432	CCQ1_SCHPO	Coiled-coil quantitatively-enriched protein 1	18535244	Fission yeast Pot1-Tpp1 protects telomeres and regulates telomere length.

P06780	RHO1_YEAST	GTP-binding protein RHO1	8846785	A downstream target of RHO1 small GTP-binding protein is PKC1, a homolog of protein kinase C, which leads to activation of the MAP kinase cascade in Saccharomyces cerevisiae.

Q39238	TSL_ARATH	Serine/threonine-protein kinase TOUSLED	8252629	The TOUSLED gene in Arabidopsis thaliana encodes a protein kinase homologue that is required for leaf and flower development.

P56705	WNT4_HUMAN	Protein Wnt-4	8168088	Differential expression of human Wnt genes 2, 3, 4, and 7B in human breast cell lines and normal and disease states of human breast tissue.

Q9FZ87	GH317_ARATH	Indole-3-acetic acid-amido synthetase GH3.17	15659623	Characterization of an Arabidopsis enzyme family that conjugates amino acids to indole-3-acetic acid.

O60934	NBN_HUMAN	Nibrin	12419185	NBS1 localizes to gamma-H2AX foci through interaction with the FHA/BRCT domain.

P40494	PRK1_YEAST	Actin-regulating kinase PRK1	10087264	Novel protein kinases Ark1p and Prk1p associate with and regulate the cortical actin cytoskeleton in budding yeast.

Q03919	RUB1_YEAST	NEDD8-like protein RUB1	15988528	The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae.

Q9ZPR4	MRS25_ARATH	Magnesium transporter MRS2-5	19966073	A root-expressed magnesium transporter of the MRS2/MGT gene family in Arabidopsis thaliana allows for growth in low-Mg2+ environments.

P83659	KNL3_CYPDO	[Thr6]-bradykinin	11306139	Isolation and sequence determination of peptides in the venom of the spider wasp (Cyphononyx dorsalis) guided by matrix-assisted laser desorption/ionization time of flight (MALDI-TOF) mass spectrometry.

Q9LXT3	MBF1B_ARATH	Multiprotein-bridging factor 1b	14988493	Three Arabidopsis MBF1 homologs with distinct expression profiles play roles as transcriptional co-activators.

Q5EB52	MEST_HUMAN	Mesoderm-specific transcript homolog protein	9158153	Human PEG1/MEST, an imprinted gene on chromosome 7.

Q9LQN6	P2C04_ARATH	Probable protein phosphatase 2C 4	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P49639	HXA1_HUMAN	Homeobox protein Hox-A1	7622051	Structure and function of the HOX A1 human homeobox gene cDNA.

O74862	UTP23_SCHPO	rRNA-processing protein utp23	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P29747	CREBA_DROME	Cyclic AMP response element-binding protein A	1508208	A cyclic AMP-responsive element-binding transcriptional activator in Drosophila melanogaster, dCREB-A, is a member of the leucine zipper family.

Q9UH99	SUN2_HUMAN	SUN domain-containing protein 2	10375507	UNC-84 localizes to the nuclear envelope and is required for nuclear migration and anchoring during C. elegans development.

Q90268	PAX2A_DANRE	Paired box protein Pax-2a	9671579	A series of no isthmus (noi) alleles of the zebrafish pax2.1 gene reveals multiple signaling events in development of the midbrain- hindbrain boundary.

Q6IRB2	HES1A_XENLA	Transcription factor HES-1-A	15531363	Sequences downstream of the bHLH domain of the Xenopus hairy-related transcription factor-1 act as an extended dimerization domain that contributes to the selection of the partners.

P20133	PGTB2_YEAST	Geranylgeranyl transferase type-2 subunit beta	1903184	Dependence of Ypt1 and Sec4 membrane attachment on Bet2.

P63044	VAMP2_MOUSE	Vesicle-associated membrane protein 2	20057356	Identification of a novel Bves function: regulation of vesicular transport.

Q9V4L4	KBRAS_DROME	NF-kappa-B inhibitor-interacting Ras-like protein	10657303	A subclass of Ras proteins that regulate the degradation of IkappaB.

Q92997	DVL3_HUMAN	Segment polarity protein dishevelled homolog DVL-3	8817329	cDNA characterization and chromosomal mapping of two human homologues of the Drosophila dishevelled polarity gene.

P51801	CLCKB_HUMAN	Chloride channel protein ClC-Kb	9326936	Mutations in the chloride channel gene, CLCNKB, cause Bartter's syndrome type III.

Q9JKL5	TESC_MOUSE	Tescalcin	17717601	Tescalcin is an essential factor in megakaryocytic differentiation associated with Ets family gene expression.

Q08919	TRE1_YEAST	Uncharacterized protein TRE1	12374868	Cell surface polarization during yeast mating.

P54874	HMCS_SCHPO	Hydroxymethylglutaryl-CoA synthase	8750242	Molecular cloning and sequencing of the hcs gene, which encodes 3- hydroxy-3-methylglutaryl coenzyme A synthase of Schizosaccharomyces pombe.

Q9NWV8	MRI40_HUMAN	BRCA1-A complex subunit MERIT40	19214193	K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC- associated Brcc36 and proteasomal Poh1.

O75821	EIF3G_HUMAN	Eukaryotic translation initiation factor 3 subunit G	14688252	The j-subunit of human translation initiation factor eIF3 is required for the stable binding of eIF3 and its subcomplexes to 40 S ribosomal subunits in vitro.

Q95RA8	MOB1_DROME	Mps one binder kinase activator-like 1	18245354	The mob as tumor suppressor gene is essential for early development and regulates tissue growth in Drosophila.

O43914	TYOBP_HUMAN	TYRO protein tyrosine kinase-binding protein	17012248	Discovery of Siglec-14, a novel sialic acid receptor undergoing concerted evolution with Siglec-5 in primates.

P51523	ZNF84_HUMAN	Zinc finger protein 84	2505992	The human genome contains hundreds of genes coding for finger proteins of the Kruppel type.

Q9Y4R7	TTLL3_HUMAN	Tubulin monoglycylase TTLL3	19524510	Evolutionary divergence of enzymatic mechanisms for posttranslational polyglycylation.

P03878	SCE2_YEAST	Intron-encoded DNA endonuclease aI4	2536592	A latent intron-encoded maturase is also an endonuclease needed for intron mobility.

P30953	OR1E1_HUMAN	Olfactory receptor 1E1	1370859	Expression of members of the putative olfactory receptor gene family in mammalian germ cells.

Q32MZ4	LRRF1_HUMAN	Leucine-rich repeat flightless-interacting protein 1	9705290	Molecular cloning and characterization of a transcription regulator with homology to GC-binding factor.

Q61140	BCAR1_MOUSE	Breast cancer anti-estrogen resistance protein 1	10739664	Crk-associated substrate p130(Cas) interacts with nephrocystin and both proteins localize to cell-cell contacts of polarized epithelial cells.

Q9UUI3	SA145_SCHPO	Spliceosome-associated protein 145	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8W234	SEUSS_ARATH	Transcriptional corepressor SEUSS	16679456	AGL24, SHORT VEGETATIVE PHASE, and APETALA1 redundantly control AGAMOUS during early stages of flower development in Arabidopsis.

Q4F867	OXLA_DABRU	L-amino-acid oxidase	19523971	Purification and characterization of a new L-amino acid oxidase from Daboia russellii siamensis venom.

P31129	YDEH_ECOLI	Diguanylate cyclase YdeH	19460094	Second messenger signalling governs Escherichia coli biofilm induction upon ribosomal stress.

Q27889	PP2B2_DROME	Serine/threonine-protein phosphatase 2B catalytic subunit 2	16860743	The calcineurin regulator sra plays an essential role in female meiosis in Drosophila.

Q9SY29	PUP4_ARATH	Probable purine permease 4	10662864	A new family of high-affinity transporters for adenine, cytosine, and purine derivatives in Arabidopsis.

Q9UL51	HCN2_HUMAN	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2	9630217	Identification of a gene encoding a hyperpolarization-activated 'pacemaker' channel of brain.

Q8N0W3	FUK_HUMAN	L-fucose kinase	12056818	Identification of human L-fucose kinase amino acid sequence.

Q9Y5E6	PCDB3_HUMAN	Protocadherin beta-3	11322959	The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number.

P37398	VIV_ORYSJ	B3 domain-containing protein VP1	8673344	The seed-specific transcription factor VP1 (OSVP1) is expressed in rice suspension-cultured cells.

Q06330	SUH_HUMAN	Recombining binding protein suppressor of hairless	16530044	Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes.

Q54BM7	PPK_DICDI	Polyphosphate kinase	15701689	Inorganic polyphosphate in Dictyostelium discoideum: influence on development, sporulation, and predation.

Q9Y463	DYR1B_HUMAN	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	14593110	Phosphorylation of Ser640 in muscle glycogen synthase by DYRK family protein kinases.

Q05096	MYO1B_RAT	Myosin-Ib	8449985	Identification, characterization and cloning of myr 1, a mammalian myosin-I.

Q9Y490	TLN1_HUMAN	Talin-1	10610730	Characterization of the human talin (TLN) gene: genomic structure, chromosomal localization, and expression pattern.

Q66GS9	CP135_HUMAN	Centrosomal protein of 135 kDa	18851962	A novel function of CEP135 as a platform protein of C-NAP1 for its centriolar localization.

P92192	LCP5_DROME	Larval cuticle protein 5	9654737	Identification of proteins and developmental expression of RNAs encoded by the 65A cuticle protein gene cluster in Drosophila melanogaster.

O35716	SOCS1_MOUSE	Suppressor of cytokine signaling 1	9202127	Structure and function of a new STAT-induced STAT inhibitor.

P50279	STX2_RAT	Syntaxin-2	8938452	The epimorphin gene is highly conserved among humans, mice, and rats and maps to human chromosome 7, mouse chromosome 5, and rat chromosome 12.

O75911	DHRS3_HUMAN	Short-chain dehydrogenase/reductase 3	9705317	Molecular characterization of a novel short-chain dehydrogenase/reductase that reduces all-trans-retinal.

O59718	NEM1_SCHPO	Nuclear envelope morphology protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q13625	ASPP2_HUMAN	Apoptosis-stimulating of p53 protein 2	12694406	ASPP2 inhibits APP-BP1-mediated NEDD8 conjugation to cullin-1 and decreases APP-BP1-induced cell proliferation and neuronal apoptosis.

P04253	HCY2_LIMPO	Hemocyanin II	8518732	Crystal structure of deoxygenated Limulus polyphemus subunit II hemocyanin at 2.18-A resolution: clues for a mechanism for allosteric regulation.

O77203	PIAA_DICDI	Protein pianissimo A	9389653	A novel cytosolic regulator, Pianissimo, is required for chemoattractant receptor and G protein-mediated activation of the 12 transmembrane domain adenylyl cyclase in Dictyostelium.

Q9LVM1	AB25B_ARATH	ABC transporter B family member 25, mitochondrial	15276431	The hydrophobic proteome of mitochondrial membranes from Arabidopsis cell suspensions.

Q86W42	THOC6_HUMAN	THO complex subunit 6 homolog	15998806	Recruitment of the human TREX complex to mRNA during splicing.

Q9CQ20	M1IP1_MOUSE	Mid1-interacting protein 1	15070402	Mig12, a novel Opitz syndrome gene product partner, is expressed in the embryonic ventral midline and co-operates with Mid1 to bundle and stabilize microtubules.

P34233	ASH1_YEAST	Transcriptional regulatory protein ASH1	8625408	Asymmetric accumulation of Ash1p in postanaphase nuclei depends on a myosin and restricts yeast mating-type switching to mother cells.

Q13907	IDI1_HUMAN	Isopentenyl-diphosphate Delta-isomerase 1	8806705	Human isopentenyl diphosphate: dimethylallyl diphosphate isomerase: overproduction, purification, and characterization.

Q15111	PLCL1_HUMAN	Inactive phospholipase C-like protein 1	7633416	Identification of a novel phospholipase C family gene at chromosome 2q33 that is homozygously deleted in human small cell lung carcinoma.

Q9FN29	ATB52_ARATH	Homeobox-leucine zipper protein ATHB-52	16055682	Homeodomain leucine zipper class I genes in Arabidopsis. Expression patterns and phylogenetic relationships.

Q9UKL0	RCOR1_HUMAN	REST corepressor 1	12192000	REST repression of neuronal genes requires components of the hSWI.SNF complex.

P53920	NM111_YEAST	Pro-apoptotic serine protease NMA111	14657274	The S. cerevisiae HtrA-like protein Nma111p is a nuclear serine protease that mediates yeast apoptosis.

P43613	ERJ5_YEAST	ER-localized J domain-containing protein 5	17157937	The Saccharomyces cerevisiae YFR041C/ERJ5 gene encoding a type I membrane protein with a J domain is required to preserve the folding capacity of the endoplasmic reticulum.

P36150	SUMT_YEAST	Uroporphyrinogen-III C-methyltransferase	10051442	The role of Saccharomyces cerevisiae Met1p and Met8p in sirohaem and cobalamin biosynthesis.

Q7TSD4	SPATL_MOUSE	Protein SPATIAL	17196196	Dynamic distribution of Spatial during mouse spermatogenesis and its interaction with the kinesin KIF17b.

P0AAB4	UBID_ECOLI	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	782527	Membrane-associated reactions in ubiquinone biosynthesis in Escherichia coli. 3-Octaprenyl-4-hydroxybenzoate carboxy-lyase.

Q06639	RSC3_YEAST	Chromatin structure-remodeling complex protein RSC3	12183366	Chromatin remodeling by RSC involves ATP-dependent DNA translocation.

Q0WQG8	GTG2_ARATH	GPCR-type G protein 2	19135895	Two novel GPCR-type G proteins are abscisic acid receptors in Arabidopsis.

Q8BGW3	BHE23_MOUSE	Class E basic helix-loop-helix protein 23	11863370	BHLHB4 is a bHLH transcriptional regulator in pancreas and brain that marks the dimesencephalic boundary.

Q8TDS4	G109A_HUMAN	G-protein coupled receptor 109A	17932499	Neutrophil apoptosis mediated by nicotinic acid receptors (GPR109A).

Q9Z0H3	SNF5_MOUSE	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1	17640523	An essential switch in subunit composition of a chromatin remodeling complex during neural development.

Q6TEM9	MYLIA_DANRE	E3 ubiquitin-protein ligase MYLIP-A	14651927	The zebrafish band 4.1 member Mir is involved in cell movements associated with gastrulation.

P13864	DNMT1_MOUSE	DNA (cytosine-5)-methyltransferase 1	17576694	Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation.

Q94F62	BAK1_ARATH	BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1	12150929	BAK1, an Arabidopsis LRR receptor-like protein kinase, interacts with BRI1 and modulates brassinosteroid signaling.

P14681	KSS1_YEAST	Mitogen-activated protein kinase KSS1	8918885	Two novel targets of the MAP kinase Kss1 are negative regulators of invasive growth in the yeast Saccharomyces cerevisiae.

Q9VFJ3	HTRA2_DROME	Serine protease HTRA2, mitochondrial	17397804	Evolution of mitochondrial cell death pathway: Proapoptotic role of HtrA2/Omi in Drosophila.

Q9UJA5	TRM6_HUMAN	tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6	16043508	The bipartite structure of the tRNA m1A58 methyltransferase from S. cerevisiae is conserved in humans.

Q96BN2	TADA1_HUMAN	Transcriptional adapter 1	11564863	Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage- binding factors in vivo.

Q9UT87	IMG1_SCHPO	60S ribosomal protein subunit img1, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q84M92	ARP4_ARATH	Actin-related protein 4	15743449	Silencing the nuclear actin-related protein AtARP4 in Arabidopsis has multiple effects on plant development, including early flowering and delayed floral senescence.

P25336	MSH3_YEAST	DNA mismatch repair protein MSH3	14562095	Global analysis of protein localization in budding yeast.

Q13464	ROCK1_HUMAN	Rho-associated protein kinase 1	8617235	The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase.

P01737	TVA3_HUMAN	T-cell receptor alpha chain V region PY14	3873654	Analysis of cDNA clones specific for human T cells and the alpha and beta chains of the T-cell receptor heterodimer from a human T-cell line.

P20718	GRAH_HUMAN	Granzyme H	2402757	Characterization of a novel, human cytotoxic lymphocyte-specific serine protease cDNA clone (CSP-C).

Q17353	PAR3_CAEEL	Partitioning defective protein 3	13129846	C. elegans PAR-3 and PAR-6 are required for apicobasal asymmetries associated with cell adhesion and gastrulation.

Q12420	SNU66_YEAST	66 kDa U4/U6.U5 small nuclear ribonucleoprotein component	10377396	Purification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins.

Q8BWM0	PGES2_MOUSE	Prostaglandin E synthase 2	12050152	A novel transactivating factor that regulates interferon-gamma- dependent gene expression.

P40454	PTPA1_YEAST	Serine/threonine-protein phosphatase 2A activator 1	12952889	A novel and essential mechanism determining specificity and activity of protein phosphatase 2A (PP2A) in vivo.

O94538	SNU66_SCHPO	U4/U6.U5 tri-snRNP-associated protein snu66	15620657	Ubiquitin-like protein Hub1 is required for pre-mRNA splicing and localization of an essential splicing factor in fission yeast.

Q62070	PIM2_MOUSE	Serine/threonine-protein kinase pim-2	12869584	The serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitor.

P83362	SPCS1_CANFA	Signal peptidase complex subunit 1	3511473	Purification of microsomal signal peptidase as a complex.

P21918	DRD5_HUMAN	D(1B) dopamine receptor	10531415	N-linked glycosylation is required for plasma membrane localization of D5, but not D1, dopamine receptors in transfected mammalian cells.

Q9P768	YI26_SCHPO	Uncharacterized amino-acid permease P7G5.06	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9WTV5	PSMD9_RAT	26S proteasome non-ATPase regulatory subunit 9	10567574	Bridge-1, a novel PDZ-domain coactivator of E2A-mediated regulation of insulin gene transcription.

Q6I9Y2	THOC7_HUMAN	THO complex subunit 7 homolog	17190602	Human mRNA export machinery recruited to the 5' end of mRNA.

Q9R237	JIP1_RAT	C-Jun-amino-terminal kinase-interacting protein 1	9442013	IB1, a JIP-1-related nuclear protein present in insulin-secreting cells.

P0AAI1	SSUB_ECOLI	Aliphatic sulfonates import ATP-binding protein SsuB	10506196	The Escherichia coli ssuEADCB gene cluster is required for the utilization of sulfur from aliphatic sulfonates and is regulated by the transcriptional activator Cbl.

Q6P1J9	CDC73_HUMAN	Parafibromin	17113272	BCL9-2 binds Arm/beta-catenin in a Tyr142-independent manner and requires Pygopus for its function in Wg/Wnt signaling.

Q9H9Z2	LN28A_HUMAN	Protein lin-28 homolog A	17617744	Localization of the developmental timing regulator Lin28 to mRNP complexes, P-bodies and stress granules.

P20594	ANPRB_HUMAN	Atrial natriuretic peptide receptor 2	10082481	Structure of the type B human natriuretic peptide receptor gene and association of a novel microsatellite polymorphism with essential hypertension.

Q16512	PKN1_HUMAN	Serine/threonine-protein kinase N1	16611232	A Salmonella type III secretion effector interacts with the mammalian serine/threonine protein kinase PKN1.

Q9BV57	MTND_HUMAN	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase	14718544	Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein-1 is a new member of the cupin superfamily. A possible multifunctional protein acting as an invasion suppressor down- regulated in tumors.

Q9NY61	AATF_HUMAN	Protein AATF	15207272	AATF protects neural cells against oxidative damage induced by amyloid beta-peptide.

Q01097	NMDE2_MOUSE	Glutamate [NMDA] receptor subunit epsilon-2	17329427	NMDA receptor function and NMDA receptor-dependent phosphorylation of huntingtin is altered by the endocytic protein HIP1.

P53999	TCP4_HUMAN	Activated RNA polymerase II transcriptional coactivator p15	8062391	Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes.

Q15554	TERF2_HUMAN	Telomeric repeat-binding factor 2	9476899	TRF2 protects human telomeres from end-to-end fusions.

P0AA43	RSUA_ECOLI	Ribosomal small subunit pseudouridine synthase A	10376875	16S ribosomal RNA pseudouridine synthase RsuA of Escherichia coli: deletion, mutation of the conserved Asp102 residue, and sequence comparison among all other pseudouridine synthases.

Q8LF21	DRP1C_ARATH	Dynamin-related protein 1C	12834397	The dynamin-like protein ADL1C is essential for plasma membrane maintenance during pollen maturation.

Q8VIM5	MYCD_MOUSE	Myocardin	11439182	Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor.

Q9JKE7	T2R41_RAT	Taste receptor type 2 member 41	10761934	A novel family of mammalian taste receptors.

Q8NIP8	WTF12_SCHPO	Uncharacterized protein wtf12	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8I8U6	FEM3_CAEBR	Sex-determination protein fem-3	12477393	Rapid coevolution of the nematode sex-determining genes fem-3 and tra-2.

P42264	GRIK3_RAT	Glutamate receptor, ionotropic kainate 3	9390526	Rat GluR7 and a carboxy-terminal splice variant, GluR7b, are functional kainate receptor subunits with a low sensitivity to glutamate.

Q9FKB5	KRP3_ARATH	Cyclin-dependent kinase inhibitor 3	11449057	Functional analysis of cyclin-dependent kinase inhibitors of Arabidopsis.

P30566	PUR8_HUMAN	Adenylosuccinate lyase	10888601	Human adenylosuccinate lyase (ADSL), cloning and characterization of full-length cDNA and its isoform, gene structure and molecular basis for ADSL deficiency in six patients.

O42173	PV1_XENLA	Homeobox protein pv.1	8692829	A novel homeobox gene PV.1 mediates induction of ventral mesoderm in Xenopus embryos.

Q01730	RSU1_MOUSE	Ras suppressor protein 1	1508180	Isolation of rsp-1, a novel cDNA capable of suppressing v-Ras transformation.

Q8K4J2	COE4_MOUSE	Transcription factor COE4	12139918	Cloning of a novel Olf-1/EBF-like gene, O/E-4, by degenerate oligo- based direct selection.

O15320	CTGE5_HUMAN	Cutaneous T-cell lymphoma-associated antigen 5	9356211	cDNA cloning and chromosomal mapping of a predicted coiled-coil proline-rich protein immunogenic in meningioma patients.

Q09161	NCBP1_HUMAN	Nuclear cap-binding protein subunit 1	7651522	A cap-binding protein complex mediating U snRNA export.

P39717	GPB2_YEAST	Guanine nucleotide-binding protein subunit beta 2	14562095	Global analysis of protein localization in budding yeast.

Q06665	RAD34_YEAST	DNA repair protein RAD34	14562095	Global analysis of protein localization in budding yeast.

P27140	CAHC_ARATH	Carbonic anhydrase, chloroplastic	12766230	Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.

O74417	YJL4_SCHPO	Uncharacterized protein C14G10.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9FLP0	MA651_ARATH	65-kDa microtubule-associated protein 1	15557096	In vivo dynamics and differential microtubule-binding activities of MAP65 proteins.

P01298	PAHO_HUMAN	Pancreatic prohormone	2997153	Exons of the human pancreatic polypeptide gene define functional domains of the precursor.

Q9H310	RHBG_HUMAN	Ammonium transporter Rh type B	15611082	The ammonium transporter RhBG: requirement of a tyrosine-based signal and ankyrin-G for basolateral targeting and membrane anchorage in polarized kidney epithelial cells.

Q9Y295	DRG1_HUMAN	Developmentally-regulated GTP-binding protein 1	9824680	SCL binds the human homologue of DRG in vivo.

P68871	HBB_HUMAN	Hemoglobin subunit beta	10588683	Ancient origins of nitric oxide signaling in biological systems.

O88846	RNF4_RAT	E3 ubiquitin ligase RNF4	18408734	RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation.

Q9ESR9	ABCA2_RAT	ATP-binding cassette sub-family A member 2	10970803	Cloning, characterization and tissue distribution of the rat ATP- binding cassette (ABC) transporter ABC2/ABCA2.

O75771	RA51D_HUMAN	DNA repair protein RAD51 homolog 4	9570954	Identification, characterization, and genetic mapping of Rad51d, a new mouse and human RAD51/RecA-related gene.

P47901	V1BR_HUMAN	Vasopressin V1b receptor	7805841	Cloning and characterization of the human V3 pituitary vasopressin receptor.

P47119	HAM1_YEAST	Protein HAM1	8789257	HAM1, the gene controlling 6-N-hydroxylaminopurine sensitivity and mutagenesis in the yeast Saccharomyces cerevisiae.

Q8RWZ1	SUB_ARATH	Protein STRUBBELIG	15618487	Positional signaling mediated by a receptor-like kinase in Arabidopsis.

O42781	MAPK2_PNECA	Mitogen-activated protein kinase 2	9688951	Characterization of a mitogen-activated protein kinase from Pneumocystis carinii.

P61960	UFM1_HUMAN	Ubiquitin-fold modifier 1	15071506	A novel protein-conjugating system for Ufm1, a ubiquitin-fold modifier.

Q90693	PTC1_CHICK	Protein patched homolog 1	8620849	Conservation in hedgehog signaling: induction of a chicken patched homolog by Sonic hedgehog in the developing limb.

A3BMZ5	BGL26_ORYSJ	Beta-glucosidase 26	19766588	Rice family GH1 glycoside hydrolases with beta-D-glucosidase and beta-D-mannosidase activities.

Q9LQL0	GCSH2_ARATH	Probable glycine cleavage system H protein 2, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q99623	PHB2_HUMAN	Prohibitin-2	10359819	An estrogen receptor-selective coregulator that potentiates the effectiveness of antiestrogens and represses the activity of estrogens.

P0AFL1	POTI_ECOLI	Putrescine transport system permease protein potI	8416922	Characteristics of the operon for a putrescine transport system that maps at 19 minutes on the Escherichia coli chromosome.

Q10576	P4HA1_CAEEL	Prolyl 4-hydroxylase subunit alpha-1	10805750	Prolyl 4-hydroxylase is an essential procollagen-modifying enzyme required for exoskeleton formation and the maintenance of body shape in the nematode Caenorhabditis elegans.

P0A6J8	DDLA_ECOLI	D-alanine--D-alanine ligase A	1993184	Existence of two D-alanine:D-alanine ligases in Escherichia coli: cloning and sequencing of the ddlA gene and purification and characterization of the DdlA and DdlB enzymes.

O95436	NPT2B_HUMAN	Sodium-dependent phosphate transport protein 2B	10329428	Cloning and functional characterization of a sodium-dependent phosphate transporter expressed in human lung and small intestine.

P38555	YPT31_YEAST	GTP-binding protein YPT31/YPT8	9151665	Two new Ypt GTPases are required for exit from the yeast trans-Golgi compartment.

Q9ES83	POPD1_MOUSE	Blood vessel epicardial substance	16188940	Bves modulates epithelial integrity through an interaction at the tight junction.

Q02045	MYL5_HUMAN	Myosin light chain 5	1284596	The genomic organization of a novel regulatory myosin light chain gene (MYL5) that maps to chromosome 4p16.3 and shows different patterns of expression between primates.

P22310	UD14_HUMAN	UDP-glucuronosyltransferase 1-4	1898728	Cloning of two human liver bilirubin UDP-glucuronosyltransferase cDNAs with expression in COS-1 cells.

P97789	XRN1_MOUSE	5'-3' exoribonuclease 1	9049243	A mouse cytoplasmic exoribonuclease (mXRN1) with preference for G4 tetraplex substrates.

P30680	SSR2_RAT	Somatostatin receptor type 2	1374909	Expression cloning of a rat brain somatostatin receptor cDNA.

P22282	22P1_RAT	Cystatin-related protein 1	8262963	A complex response element in intron 1 of the androgen-regulated 20- kDa protein gene displays cell type-dependent androgen receptor specificity.

O04161	AMT12_SOLLC	Ammonium transporter 1 member 2	10743657	Differential regulation of three functional ammonium transporter genes by nitrogen in root hairs and by light in leaves of tomato.

O60266	ADCY3_HUMAN	Adenylate cyclase type 3	8476432	A novel adenylyl cyclase sequence cloned from the human erythroleukemia cell line.

Q5KU26	COL12_HUMAN	Collectin-12	11162630	Molecular cloning and functional characterization of a human scavenger receptor with C-type lectin (SRCL), a novel member of a scavenger receptor family.

Q92207	HOG1_CANAL	Mitogen-activated protein kinase HOG1	15817773	The Pbs2 MAP kinase kinase is essential for the oxidative-stress response in the fungal pathogen Candida albicans.

Q9BZQ8	NIBAN_HUMAN	Protein Niban	16949643	A novel tumor marker, Niban, is expressed in subsets of thyroid tumors and Hashimoto's thyroiditis.

P34691	FEM3_CAEEL	Sex-determination protein fem-3	17609115	A CUL-2 ubiquitin ligase containing three FEM proteins degrades TRA-1 to regulate C. elegans sex determination.

O00303	EIF3F_HUMAN	Eukaryotic translation initiation factor 3 subunit F	18599441	Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3.

Q9EQ14	IL23A_MOUSE	Interleukin-23 subunit alpha	11114383	Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12.

Q16348	S15A2_HUMAN	Solute carrier family 15 member 2	7756356	Molecular cloning of PEPT 2, a new member of the H+/peptide cotransporter family, from human kidney.

P05709	SIM_DROME	Protein single-minded	12221007	Novel behavioral and developmental defects associated with Drosophila single-minded.

P47130	CSN12_YEAST	Cop9 signalosome complex subunit 12	12446563	COP9 signalosome components play a role in the mating pheromone response of S. cerevisiae.

Q9JHH5	CXL11_MOUSE	C-X-C motif chemokine 11	10828609	Cloning, genomic sequence, and chromosome mapping of scyb11, the murine homologue of SCYB11 (alias betaR1/H174/SCYB9B/I-TAC/IP- 9/CXCL11).

O60573	IF4E2_HUMAN	Eukaryotic translation initiation factor 4E type 2	9582349	Cloning and characterization of 4EHP, a novel mammalian eIF4E-related cap-binding protein.

P09917	LOX5_HUMAN	Arachidonate 5-lipoxygenase	2829172	Molecular cloning and amino acid sequence of human 5-lipoxygenase.

Q02955	IL1R1_RAT	Interleukin-1 receptor type 1	7684399	An mRNA homologous to interleukin-1 receptor type I is expressed in cultured rat sympathetic ganglia.

Q15819	UB2V2_HUMAN	Ubiquitin-conjugating enzyme E2 variant 2	10089880	Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair.

O14470	SSR2_SCHPO	SWI/SNF and RSC complexes subunit ssr2	18622392	Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast.

Q7ZSX3	PTF1A_DANRE	Pancreas transcription factor 1 subunit alpha	15183727	Differential requirement for ptf1a in endocrine and exocrine lineages of developing zebrafish pancreas.

P01123	YPT1_YEAST	GTP-binding protein YPT1	7593181	The Ypt1 GTPase is essential for the first two steps of the yeast secretory pathway.

P25349	YCP4_YEAST	Flavoprotein-like protein YCP4	19064668	Plasma membrane microdomains regulate turnover of transport proteins in yeast.

O15061	SYNEM_HUMAN	Synemin	18028034	Human alpha-synemin interacts directly with vinculin and metavinculin.

O23680	TOC33_ARATH	Translocase of chloroplast 33, chloroplastic	12938931	Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis.

Q60843	KLF2_MOUSE	Krueppel-like factor 2	11375995	Lung Krueppel-like factor contains an autoinhibitory domain that regulates its transcriptional activation by binding WWP1, an E3 ubiquitin ligase.

Q96251	ATPO_ARATH	ATP synthase subunit O, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q7KQZ4	LOLA3_DROME	Longitudinals lacking protein, isoforms A/B/D/L	12538650	A developmentally regulated splice variant from the complex lola locus encoding multiple different zinc finger domain proteins interacts with the chromosomal kinase JIL-1.

P05067	A4_HUMAN	Amyloid beta A4 protein	11877420	Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc.

P35225	IL13_HUMAN	Interleukin-13	8096327	Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses.

Q562F6	SGOL2_HUMAN	Shugoshin-like 2	16541025	Shugoshin collaborates with protein phosphatase 2A to protect cohesin.

Q60644	NR1H2_MOUSE	Oxysterols receptor LXR-beta	7760852	Isolation of proteins that interact specifically with the retinoid X receptor: two novel orphan receptors.

Q9ER30	KBTBA_RAT	Kelch repeat and BTB domain-containing protein 10	12692149	New N-RAP-binding partners alpha-actinin, filamin and Krp1 detected by yeast two-hybrid screening: implications for myofibril assembly.

Q8IS21	GEFB_DICDI	Ras guanine nucleotide exchange factor B	15740584	Gamete fusion and cytokinesis preceding zygote establishment in the sexual process of Dictyostelium discoideum.

Q13029	PRDM2_HUMAN	PR domain zinc finger protein 2	7590293	Identification and cloning of the G3B cDNA encoding a 3' segment of a protein binding to GATA-3.

Q9Y7R3	CND2_SCHPO	Condensin complex subunit 2	12000964	Cnd2 has dual roles in mitotic condensation and interphase.

P16310	GHR_RAT	Growth hormone receptor	8063815	Domains of the growth hormone receptor required for association and activation of JAK2 tyrosine kinase.

O88708	ORC4_MOUSE	Origin recognition complex subunit 4	10460412	Identification and characterization of MmORC4 and MmORC5, two subunits of the mouse origin of replication recognition complex.

P0AFD6	NUOI_ECOLI	NADH-quinone oxidoreductase subunit I	7607227	Isolation and characterization of the proton-translocating NADH: ubiquinone oxidoreductase from Escherichia coli.

Q27934	PHYL_DROME	Protein phyllopod	11526076	A dual function of phyllopod in Drosophila external sensory organ development: cell fate specification of sensory organ precursor and its progeny.

Q9N4X8	GSTPA_CAEEL	Glutathione S-transferase P 10	16164425	Lifespan and stress resistance of Caenorhabditis elegans are increased by expression of glutathione transferases capable of metabolizing the lipid peroxidation product 4-hydroxynonenal.

O35381	AN32A_MOUSE	Acidic leucine-rich nuclear phosphoprotein 32 family member A	17557114	The role of LANP and ataxin 1 in E4F-mediated transcriptional repression.

O00144	FZD9_HUMAN	Frizzled-9	9147651	A novel human homologue of the Drosophila frizzled wnt receptor gene binds wingless protein and is in the Williams syndrome deletion at 7q11.23.

P29353	SHC1_HUMAN	SHC-transforming protein 1	7541045	Non-SH2 domains within insulin receptor substrate-1 and SHC mediate their phosphotyrosine-dependent interaction with the NPEY motif of the insulin-like growth factor I receptor.

O88621	FOXH1_MOUSE	Forkhead box protein H1	10349617	A mouse homologue of FAST-1 transduces TGF beta superfamily signals and is expressed during early embryogenesis.

P29466	CASP1_HUMAN	Caspase-1	7876192	Cloning and expression of four novel isoforms of human interleukin-1 beta converting enzyme with different apoptotic activities.

P21462	FPR1_HUMAN	fMet-Leu-Phe receptor	2161213	Synthesis and use of a novel N-formyl peptide derivative to isolate a human N-formyl peptide receptor cDNA.

Q9Y696	CLIC4_HUMAN	Chloride intracellular channel protein 4	10793131	Identification of a novel member of the chloride intracellular channel gene family (CLIC5) that associates with the actin cytoskeleton of placental microvilli.

P39014	MET30_YEAST	F-box protein MET30	9499404	Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box protein complexes that regulate cell division and methionine biosynthesis in yeast.

P50229	CCL3_RAT	C-C motif chemokine 3	7779098	Molecular cloning and posttranscriptional regulation of macrophage inflammatory protein-1 alpha in alveolar macrophages.

O15075	DCLK1_HUMAN	Serine/threonine-protein kinase DCLK1	10036192	DCAMKL1, a brain-specific transmembrane protein on 13q12.3 that is similar to doublecortin (DCX).

Q38830	IAA12_ARATH	Auxin-responsive protein IAA12	18258861	TOPLESS mediates auxin-dependent transcriptional repression during Arabidopsis embryogenesis.

P33339	TFC4_YEAST	Transcription factor tau 131 kDa subunit	2180956	Purification and characterization of Saccharomyces cerevisiae transcription factor TFIIIC. Polypeptide composition defined with polyclonal antibodies.

P00630	PA2_APIME	Phospholipase A2	2274788	Crystal structure of bee-venom phospholipase A2 in a complex with a transition-state analogue.

Q555X4	GNT15_DICDI	Glycosyltransferase-like protein gnt15	17588537	Dictyostelium gnt15 encodes a protein with similarity to LARGE and plays an essential role in development.

Q00889	PSG6_HUMAN	Pregnancy-specific beta-1-glycoprotein 6	1690992	The human pregnancy-specific glycoprotein genes are tightly linked on the long arm of chromosome 19 and are coordinately expressed.

Q16531	DDB1_HUMAN	DNA damage-binding protein 1	17041588	CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation.

P31652	SC6A4_RAT	Sodium-dependent serotonin transporter	12944413	Glycosyl modification facilitates homo- and hetero-oligomerization of the serotonin transporter. A specific role for sialic acid residues.

P51648	AL3A2_HUMAN	Fatty aldehyde dehydrogenase	8528251	Sjogren-Larsson syndrome is caused by mutations in the fatty aldehyde dehydrogenase gene.

P37293	NAT2_YEAST	N-terminal acetyltransferase 2	8175741	NAT2, an essential gene encoding methionine N alpha-acetyltransferase in the yeast Saccharomyces cerevisiae.

Q8IEF6	MYB1_PLAF7	Myb1 protein	15500927	Characterization of PfMyb1 transcription factor during erythrocytic development of 3D7 and F12 Plasmodium falciparum clones.

P45379	TNNT2_HUMAN	Troponin T, cardiac muscle	15542288	Severe disease expression of cardiac troponin C and T mutations in patients with idiopathic dilated cardiomyopathy.

P06753	TPM3_HUMAN	Tropomyosin alpha-3 chain	3418707	Organization of the hTMnm gene. Implications for the evolution of muscle and non-muscle tropomyosins.

P49678	IAA2_ARATH	Auxin-responsive protein IAA2	7658471	The PS-IAA4/5-like family of early auxin-inducible mRNAs in Arabidopsis thaliana.

P13107	CP2B3_RAT	Cytochrome P450 2B3	3396451	A constitutive member of the rat cytochrome P450IIB subfamily: full- length coding sequence of the P450IIB3 cDNA.

P90916	LIN53_CAEEL	Probable histone-binding protein lin-53	17075059	Some C. elegans class B synthetic multivulva proteins encode a conserved LIN-35 Rb-containing complex distinct from a NuRD-like complex.

P17812	PYRG1_HUMAN	CTP synthase 1	2113467	Molecular cloning of the human CTP synthetase gene by functional complementation with purified human metaphase chromosomes.

Q9FDX8	HD1_ORYSJ	Zinc finger protein HD1	11148291	Hd1, a major photoperiod sensitivity quantitative trait locus in rice, is closely related to the Arabidopsis flowering time gene CONSTANS.

O43017	SWD3_SCHPO	Set1 complex component swd3	12488447	High conservation of the Set1/Rad6 axis of histone 3 lysine 4 methylation in budding and fission yeasts.

Q8UVX0	PIWL1_DANRE	Piwi-like protein 1	18833190	Zili is required for germ cell differentiation and meiosis in zebrafish.

Q5ZAY9	CKX5_ORYSJ	Cytokinin dehydrogenase 5	12721786	Structure and function of cytokinin oxidase/dehydrogenase genes of maize, rice, Arabidopsis and other species.

P32494	NGG1_YEAST	Chromatin-remodeling complexes subunit NGG1	9674426	A subset of TAF(II)s are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulation.

Q9QYN3	KLK11_MOUSE	Kallikrein-11	11072088	cDNA cloning and tissue-specific splicing variants of mouse hippostasin/TLSP (PRSS20).

Q8HZT6	RDH10_BOVIN	Retinol dehydrogenase 10	12407145	Cloning and characterization of a novel all-trans retinol short-chain dehydrogenase/reductase from the RPE.

Q8LGA5	ATL31_ARATH	E3 ubiquitin-protein ligase ATL31	17722694	Identification of 118 Arabidopsis transcription factor and 30 ubiquitin-ligase genes responding to chitin, a plant-defense elicitor.

Q8N122	RPTOR_HUMAN	Regulatory-associated protein of mTOR	12150925	mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the growth machinery.

Q9NNW7	TRXR2_HUMAN	Thioredoxin reductase 2, mitochondrial	10455115	Redox regulation of cell signaling by selenocysteine in mammalian thioredoxin reductases.

Q94F88	CMT3_ARATH	DNA (cytosine-5)-methyltransferase CMT3	11459824	Arabidopsis cmt3 chromomethylase mutations block non-CG methylation and silencing of an endogenous gene.

Q12791	KCMA1_HUMAN	Calcium-activated potassium channel subunit alpha-1	7573516	A human calcium-activated potassium channel gene expressed in vascular smooth muscle.

O70531	S26A2_RAT	Sulfate transporter	9575183	Functional analysis of diastrophic dysplasia sulfate transporter. Its involvement in growth regulation of chondrocytes mediated by sulfated proteoglycans.

Q9NRE1	MMP26_HUMAN	Matrix metalloproteinase-26	10987280	Matrilysin-2, a new matrix metalloproteinase expressed in human tumors and showing the minimal domain organization required for secretion, latency, and activity.

Q9LSQ4	GH36_ARATH	Indole-3-acetic acid-amido synthetase GH3.6	11169197	DFL1, an auxin-responsive GH3 gene homologue, negatively regulates shoot cell elongation and lateral root formation, and positively regulates the light response of hypocotyl length.

Q16186	ADRM1_HUMAN	Proteasomal ubiquitin receptor ADRM1	16990800	A novel proteasome-interacting protein recruits the deubiquitinating enzyme UCH37 to 26S proteasomes.

P23566	UBC2_SCHPO	Ubiquitin-conjugating enzyme E2 2	9710635	A novel function of the DNA repair gene rhp6 in mating-type silencing by chromatin remodeling in fission yeast.

P0ABE2	BOLA_ECOLI	Protein BolA	2684651	Induction of a growth-phase-dependent promoter triggers transcription of bolA, an Escherichia coli morphogene.

Q9LR47	IP5P3_ARATH	Type I inositol-1,4,5-trisphosphate 5-phosphatase CVP2	15100402	COTYLEDON VASCULAR PATTERN2-mediated inositol (1,4,5) triphosphate signal transduction is essential for closed venation patterns of Arabidopsis foliar organs.

Q9P6L2	YKQE_SCHPO	SET domain-containing protein C688.14	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O55164	MPDZ_RAT	Multiple PDZ domain protein	12403818	Distinct claudins and associated PDZ proteins form different autotypic tight junctions in myelinating Schwann cells.

Q9JJY3	NSMA2_MOUSE	Sphingomyelin phosphodiesterase 3	10823942	Cloning and characterization of the mammalian brain-specific, Mg2+- dependent neutral sphingomyelinase.

Q55835	FUTA2_SYNY3	Iron uptake protein A2	10998049	Proteomics of Synechocystis sp. strain PCC 6803. Identification of periplasmic proteins in cells grown at low and high salt concentrations.

Q9HGN5	YO45_SCHPO	Putative E3 ubiquitin-protein ligase C36B7.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8NF91	SYNE1_HUMAN	Nesprin-1	12808039	Golgi localization of Syne-1.

Q9GZC8	SID1_CAEEL	Systemic RNA interference defective protein 1	12970568	Transport of dsRNA into cells by the transmembrane protein SID-1.

P02833	ANTP_DROME	Homeotic protein antennapedia	6330741	Structural relationships among genes that control development: sequence homology between the Antennapedia, Ultrabithorax, and fushi tarazu loci of Drosophila.

Q01433	AMPD2_HUMAN	AMP deaminase 2	8764830	Cloning, sequence and characterization of the human AMPD2 gene: evidence for transcriptional regulation by two closely spaced promoters.

O13881	CLR2_SCHPO	Cryptic loci regulator 2	15317867	A novel type of silencing factor, Clr2, is necessary for transcriptional silencing at various chromosomal locations in the fission yeast Schizosaccharomyces pombe.

O15226	NKRF_HUMAN	NF-kappa-B-repressing factor	10562553	Constitutive silencing of IFN-beta promoter is mediated by NRF (NF- kB-repressing factor), a nuclear inhibitor of NF-kB.

O95551	TYDP2_HUMAN	Tyrosyl-DNA phosphodiesterase 2	18039968	Ttrap is an essential modulator of Smad3-dependent Nodal signaling during zebrafish gastrulation and left-right axis determination.

Q13822	ENPP2_HUMAN	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	1733949	Identification, purification, and partial sequence analysis of autotaxin, a novel motility-stimulating protein.

Q90XH3	RBTN2_XENLA	Rhombotin-2	11493549	Primitive erythropoiesis in the Xenopus embryo: the synergistic role of LMO-2, SCL and GATA-binding proteins.

P62191	PRS4_HUMAN	26S protease regulatory subunit 4	1429620	Subunit 4 of the 26 S protease is a member of a novel eukaryotic ATPase family.

P25445	TNR6_HUMAN	Tumor necrosis factor receptor superfamily member 6	15465831	A death receptor-associated anti-apoptotic protein, BRE, inhibits mitochondrial apoptotic pathway.

P24892	NU4M_CAEEL	NADH-ubiquinone oxidoreductase chain 4	1551572	The mitochondrial genomes of two nematodes, Caenorhabditis elegans and Ascaris suum.

P47122	NPA3_YEAST	GTPase NPA3	14562095	Global analysis of protein localization in budding yeast.

P08195	4F2_HUMAN	4F2 cell-surface antigen heavy chain	3036867	Primary structure of the human 4F2 antigen heavy chain predicts a transmembrane protein with a cytoplasmic NH2 terminus.

Q39024	MPK4_ARATH	Mitogen-activated protein kinase 4	11123804	Various abiotic stresses rapidly activate Arabidopsis MAP kinases ATMPK4 and ATMPK6.

Q9BS18	APC13_HUMAN	Anaphase-promoting complex subunit 13	18485873	Mechanism of ubiquitin-chain formation by the human anaphase- promoting complex.

O76039	CDKL5_HUMAN	Cyclin-dependent kinase-like 5	16935860	Functional consequences of mutations in CDKL5, an X-linked gene involved in infantile spasms and mental retardation.

P38129	TAF5_YEAST	Transcription initiation factor TFIID subunit 5	12446794	The novel SLIK histone acetyltransferase complex functions in the yeast retrograde response pathway.

P38429	SAP30_YEAST	Transcriptional regulatory protein SAP30	16314178	Stable incorporation of sequence specific repressors Ash1 and Ume6 into the Rpd3L complex.

O00299	CLIC1_HUMAN	Chloride intracellular channel protein 1	9139710	Molecular cloning and expression of a chloride ion channel of cell nuclei.

O95264	5HT3B_HUMAN	5-hydroxytryptamine receptor 3B	9950429	The 5-HT3B subunit is a major determinant of serotonin-receptor function.

Q99607	ELF4_HUMAN	ETS-related transcription factor Elf-4	14625302	Myeloid ELF1-like factor is a potent activator of interleukin-8 expression in hematopoietic cells.

Q8GZ17	COBL7_ARATH	COBRA-like protein 7	12376623	The COBRA family of putative GPI-anchored proteins in Arabidopsis. A new fellowship in expansion.

Q9ES97	RTN3_MOUSE	Reticulon-3	19665976	A class of dynamin-like GTPases involved in the generation of the tubular ER network.

Q99612	KLF6_HUMAN	Krueppel-like factor 6	9083102	A novel human zinc finger protein that interacts with the core promoter element of a TATA box-less gene.

P29218	IMPA1_HUMAN	Inositol monophosphatase 1	1377913	cDNA cloning of human and rat brain myo-inositol monophosphatase. Expression and characterization of the human recombinant enzyme.

Q86GL4	NOXB_DICDI	Superoxide-generating NADPH oxidase heavy chain subunit B	15950752	NADPH oxidase homologs are required for normal cell differentiation and morphogenesis in Dictyostelium discoideum.

Q03330	GCN5_YEAST	Histone acetyltransferase GCN5	12446794	The novel SLIK histone acetyltransferase complex functions in the yeast retrograde response pathway.

O74808	CLR1_SCHPO	Cryptic loci regulator protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9ULX6	AKP8L_HUMAN	A-kinase anchor protein 8-like	10761695	Identification, cloning and characterization of a novel nuclear protein, HA95, homologous to A-kinase anchoring protein 95.

Q9HD26	GOPC_HUMAN	Golgi-associated PDZ and coiled-coil motif-containing protein	11384996	Association of a novel PDZ domain-containing peripheral Golgi protein with the Q-SNARE (Q-soluble N-ethylmaleimide-sensitive fusion protein (NSF) attachment protein receptor) protein syntaxin 6.

P07953	F261_RAT	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	8634242	Crystal structure of the rat liver fructose-2,6-bisphosphatase based on selenomethionine multiwavelength anomalous dispersion phases.

Q9JIR4	RIMS1_RAT	Regulating synaptic membrane exocytosis protein 1	9252191	Rim is a putative Rab3 effector in regulating synaptic-vesicle fusion.

Q810L3	CHFR_MOUSE	E3 ubiquitin-protein ligase CHFR	15793587	Chfr is required for tumor suppression and Aurora A regulation.

Q9BQA5	HINFP_HUMAN	Histone H4 transcription factor	17974976	The HiNF-P/p220NPAT cell cycle signaling pathway controls nonhistone target genes.

Q9JMB7	PIWL1_MOUSE	Piwi-like protein 1	16766680	A novel class of small RNAs in mouse spermatogenic cells.

Q922Q1	MOSC2_MOUSE	MOSC domain-containing protein 2, mitochondrial	14651853	Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.

Q9LX29	ACR4_ARATH	Serine/threonine-protein kinase-like protein ACR4	18539132	Dimerization properties of the transmembrane domains of Arabidopsis CRINKLY4 receptor-like kinase and homologs.

Q9UPX8	SHAN2_HUMAN	SH3 and multiple ankyrin repeat domains protein 2	11583995	Dynamin isoform-specific interaction with the shank/ProSAP scaffolding proteins of the postsynaptic density and actin cytoskeleton.

Q15185	TEBP_HUMAN	Prostaglandin E synthase 3	12077419	Disassembly of transcriptional regulatory complexes by molecular chaperones.

Q15116	PDCD1_HUMAN	Programmed cell death protein 1	9332365	The human PD-1 gene: complete cDNA, genomic organization, and developmentally regulated expression in B cell progenitors.

P19785	ESR1_MOUSE	Estrogen receptor	20005806	Somatic sex reprogramming of adult ovaries to testes by FOXL2 ablation.

P60335	PCBP1_MOUSE	Poly(rC)-binding protein 1	10455157	A set of highly conserved RNA-binding proteins, alphaCP-1 and alphaCP-2, implicated in mRNA stabilization, are coexpressed from an intronless gene and its intron-containing paralog.

P32899	IMP3_YEAST	U3 small nucleolar ribonucleoprotein protein IMP3	15489263	Imp3p and Imp4p mediate formation of essential U3-precursor rRNA (pre-rRNA) duplexes, possibly to recruit the small subunit processome to the pre-rRNA.

Q3MIB4	LONP2_RAT	Lon protease homolog 2, peroxisomal	14561759	Proteomic analysis of rat liver peroxisome: presence of peroxisome- specific isozyme of Lon protease.

Q9UGH3	S23A2_HUMAN	Solute carrier family 23 member 2	10471399	Human placental sodium-dependent vitamin C transporter (SVCT2): molecular cloning and transport function.

O74462	TAF6_SCHPO	Transcription initiation factor TFIID subunit 6	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P53943	AQR1_YEAST	Probable transporter AQR1	11922628	AQR1 gene (ORF YNL065w) encodes a plasma membrane transporter of the major facilitator superfamily that confers resistance to short-chain monocarboxylic acids and quinidine in Saccharomyces cerevisiae.

Q8JIM3	GHRP_RANCA	Growth hormone-releasing peptides	11796493	A novel amphibian hypothalamic neuropeptide: isolation, localization, and biological activity.

A1L1N5	HN1BA_DANRE	Hepatocyte nuclear factor 1-beta-A	18945197	hnf1b genes in zebrafish hindbrain development.

O59785	YCN8_SCHPO	Uncharacterized solute carrier family 35 member C320.08	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8CF89	TAB1_MOUSE	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1	12464436	Targeted disruption of the Tab1 gene causes embryonic lethality and defects in cardiovascular and lung morphogenesis.

P38429	SAP30_YEAST	Transcriptional regulatory protein SAP30	10388812	A general requirement for the Sin3-Rpd3 histone deacetylase complex in regulating silencing in Saccharomyces cerevisiae.

P23566	UBC2_SCHPO	Ubiquitin-conjugating enzyme E2 2	17363370	HULC, a histone H2B ubiquitinating complex, modulates heterochromatin independent of histone methylation in fission yeast.

Q9FKM7	IAA33_ARATH	Putative auxin-responsive protein IAA33	12036262	Genetics of Aux/IAA and ARF action in plant growth and development.

P30429	CED4_CAEEL	Cell death protein 4	10688797	Translocation of C. elegans CED-4 to nuclear membranes during programmed cell death.

Q91989	P5F13_XENLA	POU domain, class 5, transcription factor 1.3	1732736	Sequential expression of multiple POU proteins during amphibian early development.

Q99459	CDC5L_HUMAN	Cell division cycle 5-like protein	8917598	A cdc5+ homolog of a higher plant, Arabidopsis thaliana.

O54946	DNJB6_MOUSE	DnaJ homolog subfamily B member 6	18163532	Impaired placental trophoblast lineage differentiation in Alkbh1(-/-) mice.

Q9FH18	WIP2_ARATH	WPP domain-interacting protein 2	17600715	Anchorage of plant RanGAP to the nuclear envelope involves novel nuclear-pore-associated proteins.

O42875	SYWM_SCHPO	Tryptophanyl-tRNA synthetase, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P15398	RPA1_SCHPO	DNA-directed RNA polymerase I subunit rpa1	2537310	Essential roles of the RNA polymerase I largest subunit and DNA topoisomerases in the formation of fission yeast nucleolus.

P55211	CASP9_HUMAN	Caspase-9	8663294	ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B.

P01903	DRA_HUMAN	HLA class II histocompatibility antigen, DR alpha chain	6812963	Alpha chain of HLA-DR transplantation antigens is a member of the same protein superfamily as the immunoglobulins.

Q149L7	CRTAM_MOUSE	Cytotoxic and regulatory T-cell molecule	15811952	The tumor suppressor TSLC1/NECL-2 triggers NK-cell and CD8+ T-cell responses through the cell-surface receptor CRTAM.

Q64702	PLK4_MOUSE	Serine/threonine-protein kinase PLK4	17891141	Nucleolar release of Hand1 acts as a molecular switch to determine cell fate.

Q8K2P7	S38A1_MOUSE	Sodium-coupled neutral amino acid transporter 1	11325958	Characterization of an N-system amino acid transporter expressed in retina and its involvement in glutamine transport.

O36019	ATG13_SCHPO	Autophagy protein 13	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9DA79	DPEP3_MOUSE	Dipeptidase 3	12738806	Identification of two additional members of the membrane-bound dipeptidase family.

P36046	MIA40_YEAST	Mitochondrial intermembrane space import and assembly protein 40	14562095	Global analysis of protein localization in budding yeast.

P32354	MCM10_YEAST	Minichromosome maintenance protein 10	15201046	Mcm10 and Cdc45 cooperate in origin activation in Saccharomyces cerevisiae.

B7ZQA9	P5F12_XENLA	POU domain, class 5, transcription factor 1.2	16860542	Xenopus POU factors of subclass V inhibit activin/nodal signaling during gastrulation.

P53867	ATG4_YEAST	Cysteine protease ATG4	11149920	Membrane recruitment of Aut7p in the autophagy and cytoplasm to vacuole targeting pathways requires Aut1p, Aut2p, and the autophagy conjugation complex.

Q8BGW0	THMS1_MOUSE	Protein THEMIS	19597498	Themis, a T cell-specific protein important for late thymocyte development.

Q03164	MLL1_HUMAN	Histone-lysine N-methyltransferase MLL	1423624	Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias.

Q8NHW3	MAFA_HUMAN	Transcription factor MafA	12368292	MafA is a glucose-regulated and pancreatic beta-cell-specific transcriptional activator for the insulin gene.

O88202	LPP60_RAT	60 kDa lysophospholipase	9575212	Cloning and expression of cDNA encoding rat liver 60-kDa lysophospholipase containing an asparaginase-like region and ankyrin repeat.

Q6PIZ9	TRAT1_HUMAN	T-cell receptor-associated transmembrane adapter 1	11390434	The transmembrane adaptor protein TRIM regulates T-cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chain.

O14745	NHRF1_HUMAN	Na(+)/H(+) exchange regulatory cofactor NHE-RF1	19555689	MCC, a new interacting protein for Scrib, is required for cell migration in epithelial cells.

Q9P6R1	VRP1_SCHPO	Verprolin	16087707	Interactions of WASp, myosin-I, and verprolin with Arp2/3 complex during actin patch assembly in fission yeast.

Q9QX66	DPF1_MOUSE	Zinc finger protein neuro-d4	17640523	An essential switch in subunit composition of a chromatin remodeling complex during neural development.

P35240	MERL_HUMAN	Merlin	20178741	Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4(DCAF1) in the nucleus.

P53012	SCS3_YEAST	FIT family protein SCS3	7706223	Cloning and sequence of the SCS3 gene which is required for inositol prototrophy in Saccharomyces cerevisiae.

O60675	MAFK_HUMAN	Transcription factor MafK	9150357	Human small Maf proteins form heterodimers with CNC family transcription factors and recognize the NF-E2 motif.

P38262	SIF2_YEAST	SIR4-interacting protein SIF2	9651685	Sif2p interacts with Sir4p amino-terminal domain and antagonizes telomeric silencing in yeast.

P12398	HSP77_YEAST	Heat shock protein SSC1, mitochondrial	10464305	Stable association of 70-kDa heat shock protein induces latent multisite specificity of a unisite-specific endonuclease in yeast mitochondria.

P42574	CASP3_HUMAN	Caspase-3	7983002	CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme.

Q8INR6	DOT1L_DROME	Histone-lysine N-methyltransferase, H3 lysine-79 specific	15371351	Characterization of the grappa gene, the Drosophila histone H3 lysine 79 methyltransferase.

P47057	SNX4_YEAST	Sorting nexin-4	12048214	Cooperative binding of the cytoplasm to vacuole targeting pathway proteins, Cvt13 and Cvt20, to phosphatidylinositol 3-phosphate at the pre-autophagosomal structure is required for selective autophagy.

P63072	UBD_MOUSE	Ubiquitin D	17889673	E1-L2 activates both ubiquitin and FAT10.

P12841	FOS_RAT	Proto-oncogene c-Fos	2105492	Expression and purification of the leucine zipper and DNA-binding domains of Fos and Jun: both Fos and Jun contact DNA directly.

P41318	LST8_YEAST	Target of rapamycin complex subunit LST8	11742997	RTG-dependent mitochondria to nucleus signaling is negatively regulated by the seven WD-repeat protein Lst8p.

P68104	EF1A1_HUMAN	Elongation factor 1-alpha 1	3512269	The primary structure of the alpha subunit of human elongation factor 1. Structural aspects of guanine-nucleotide-binding sites.

Q9SAA2	CLPP6_ARATH	ATP-dependent Clp protease proteolytic subunit 6, chloroplastic	11278690	Identification of a 350-kDa ClpP protease complex with 10 different Clp isoforms in chloroplasts of Arabidopsis thaliana.

P53507	TOM7_YEAST	Mitochondrial import receptor subunit TOM7	8641278	Tom7 modulates the dynamics of the mitochondrial outer membrane translocase and plays a pathway-related role in protein import.

P84739	PALST_EUGGR	Photoactivated adenylate cyclase subunit alpha-like protein ST-	16121285	Photoactivated adenylyl cyclase (PAC) genes in the flagellate Euglena gracilis mutant strains.

P46977	STT3A_HUMAN	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A	12887896	Oligosaccharyltransferase isoforms that contain different catalytic STT3 subunits have distinct enzymatic properties.

P16501	IGF1A_XENLA	Insulin-like growth factor I-A	11944947	The IGF pathway regulates head formation by inhibiting Wnt signaling in Xenopus.

P62807	H2B1C_HUMAN	Histone H2B type 1-C/E/F/G/I	422550	Human spleen histone H2B. Isolation and amino acid sequence.

Q9NS61	KCIP2_HUMAN	Kv channel-interacting protein 2	10676964	Modulation of A-type potassium channels by a family of calcium sensors.

P38398	BRCA1_HUMAN	Breast cancer type 1 susceptibility protein	11836499	BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage.

Q13106	ZN154_HUMAN	Zinc finger protein 154	7557990	Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders.

O23680	TOC33_ARATH	Translocase of chloroplast 33, chloroplastic	12782294	Unusual nucleotide-binding properties of the chloroplast protein import receptor, atToc33.

Q62920	PDLI5_RAT	PDZ and LIM domain protein 5	10833443	ENH, containing PDZ and LIM domains, heart/skeletal muscle-specific protein, associates with cytoskeletal proteins through the PDZ domain.

P52298	NCBP2_HUMAN	Nuclear cap-binding protein subunit 2	12434151	Structural basis of m7GpppG binding to the nuclear cap-binding protein complex.

P19658	EXO70_YEAST	Exocyst complex component EXO70	10207081	Rho3 of Saccharomyces cerevisiae, which regulates the actin cytoskeleton and exocytosis, is a GTPase which interacts with Myo2 and Exo70.

P41222	PTGDS_HUMAN	Prostaglandin-H2 D-isomerase	7692978	Identification of a brain-specific human cerebrospinal fluid glycoprotein, beta-trace protein.

Q8CA03	TSCOT_MOUSE	Thymic stromal cotransporter protein	10706709	A putative 12 transmembrane domain cotransporter expressed in thymic cortical epithelial cells.

P35227	PCGF2_HUMAN	Polycomb group RING finger protein 2	8325509	Cloning and chromosome mapping of the human Mel-18 gene which encodes a DNA-binding protein with a new 'RING-finger' motif.

P39108	PEX7_YEAST	Peroxisomal targeting signal 2 receptor	7535304	PEB1 (PAS7) in Saccharomyces cerevisiae encodes a hydrophilic, intra- peroxisomal protein that is a member of the WD repeat family and is essential for the import of thiolase into peroxisomes.

Q03718	NSE5_YEAST	Non-structural maintenance of chromosome element 5	14690591	Assigning function to yeast proteins by integration of technologies.

P53930	AF9_YEAST	Protein AF-9 homolog	15045029	A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin.

Q9Y4A5	TRRAP_HUMAN	Transformation/transcription domain-associated protein	9885574	The 400 kDa subunit of the PCAF histone acetylase complex belongs to the ATM superfamily.

P46663	BKRB1_HUMAN	B1 bradykinin receptor	10422787	Molecular characterisation of cloned bradykinin B1 receptors from rat and human.

Q91VE0	S27A4_MOUSE	Long-chain fatty acid transport protein 4	12821645	Mice with targeted disruption of the fatty acid transport protein 4 (Fatp 4, Slc27a4) gene show features of lethal restrictive dermopathy.

O14235	POF5_SCHPO	Protein pof5	15147268	Molecular interactions of fission yeast Skp1 and its role in the DNA damage checkpoint.

P13351	CCNB2_XENLA	G2/mitotic-specific cyclin-B2	10465793	A novel p34cdc2 binding and activating protein that is necessary and sufficient to trigger G2/M progression in Xenopus oocytes.

P33400	PACC_YEAST	pH-response transcription factor pacC/RIM101	11050096	Alkaline response genes of Saccharomyces cerevisiae and their relationship to the RIM101 pathway.

O64645	SOC1_ARATH	MADS-box protein SOC1	18466303	SOC1 translocated to the nucleus by interaction with AGL24 directly regulates leafy.

O60248	SOX15_HUMAN	Protein SOX-15	8332506	Partial cloning of SOX-11 and SOX-12, two new human SOX genes.

P32486	KRE6_YEAST	Beta-glucan synthesis-associated protein KRE6	10601196	Localization of synthesis of beta1,6-glucan in Saccharomyces cerevisiae.

P39687	AN32A_HUMAN	Acidic leucine-rich nuclear phosphoprotein 32 family member A	8192856	Purification and characterization of two putative HLA class II associated proteins: PHAPI and PHAPII.

P21359	NF1_HUMAN	Neurofibromin	1568247	Somatic mutations in the neurofibromatosis 1 gene in human tumors.

Q06389	NCS1_YEAST	Calcium-binding protein NCS-1	10559922	Yeast homologue of neuronal frequenin is a regulator of phosphatidylinositol-4-OH kinase.

Q62277	SYPH_MOUSE	Synaptophysin	10595519	Essential roles in synaptic plasticity for synaptogyrin I and synaptophysin I.

Q02754	YP067_YEAST	Uncharacterized protein YPL067C	14562095	Global analysis of protein localization in budding yeast.

P07274	PROF_YEAST	Profilin	9698363	Structure determination and characterization of Saccharomyces cerevisiae profilin.

Q13586	STIM1_HUMAN	Stromal interaction molecule 1	20418871	A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cells.

Q9FHN6	SKS2_ARATH	Monocopper oxidase-like protein SKS2	14517339	Proteomic analysis of glycosylphosphatidylinositol-anchored membrane proteins.

O23810	YY1_ORYSJ	Protein YY1	8704128	Isolation and characterization of two cDNA clones for mRNAs that are abundantly expressed in immature anthers of rice (Oryza sativa L.).

O74464	RM22_SCHPO	54S ribosomal protein L22, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q96EP1	CHFR_HUMAN	E3 ubiquitin-protein ligase CHFR	10935642	Chfr defines a mitotic stress checkpoint that delays entry into metaphase.

Q91399	ID3A_XENLA	DNA-binding protein inhibitor ID-3-A	18710660	Hairy2 functions through both DNA-binding and non DNA-binding mechanisms at the neural plate border in Xenopus.

P28007	GAR1_YEAST	H/ACA ribonucleoprotein complex subunit 1	1531632	GAR1 is an essential small nucleolar RNP protein required for pre- rRNA processing in yeast.

O15552	FFAR2_HUMAN	Free fatty acid receptor 2	9344866	A cluster of four novel human G protein-coupled receptor genes occurring in close proximity to CD22 gene on chromosome 19q13.1.

Q9Y493	ZAN_HUMAN	Zonadhesin	9126492	Chromosome localization of the mouse zonadhesin gene and the human zonadhesin gene (ZAN).

Q8UVJ6	VANG2_DANRE	Vang-like protein 2	9808788	Functional interactions of genes mediating convergent extension, knypek and trilobite, during the partitioning of the eye primordium in zebrafish.

O94518	DIC1_SCHPO	Dynein intermediate chain 1	15509865	The p150-Glued Ssm4p regulates microtubular dynamics and nuclear movement in fission yeast.

P38932	VPS45_YEAST	Vacuolar protein sorting-associated protein 45	7720726	Yeast Vps45p is a Sec1p-like protein required for the consumption of vacuole-targeted, post-Golgi transport vesicles.

P06396	GELS_HUMAN	Gelsolin	3020431	Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain.

P14954	CECA_DROME	Cecropin-A1/A2	9725836	Molecular evolution of the Cecropin multigene family in Drosophila: functional genes vs pseudogenes.

P34163	TGL1_YEAST	Sterol esterase TGL1	10515935	Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiae.

Q8AWF5	NDC80_XENLA	Kinetochore protein NDC80 homolog	12514103	The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity.

Q10740	LKHA4_YEAST	Leukotriene A-4 hydrolase	14562095	Global analysis of protein localization in budding yeast.

Q9XF43	KCS6_ARATH	3-ketoacyl-CoA synthase 6	10330468	CUT1, an Arabidopsis gene required for cuticular wax biosynthesis and pollen fertility, encodes a very-long-chain fatty acid condensing enzyme.

Q9P7U1	YI7F_SCHPO	Uncharacterized AIM2 family protein C977.15	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O60749	SNX2_HUMAN	Sorting nexin-2	14596906	The formin-binding protein 17, FBP17, binds via a TNKS binding motif to tankyrase, a protein involved in telomere maintenance.

Q9PW56	BNP2_BOTJA	Bradykinin-potentiating and C-type natriuretic peptides	12716428	The C-type natriuretic peptide precursor of snake brain contains highly specific inhibitors of the angiotensin-converting enzyme.

O81283	TC159_ARATH	Translocase of chloroplast 159, chloroplastic	12869544	Dimerization of Toc-GTPases at the chloroplast protein import machinery.

O00237	RN103_HUMAN	E3 ubiquitin-protein ligase RNF103	10500182	RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination.

O14907	TX1B3_HUMAN	Tax1-binding protein 3	11163757	The C-terminus of human glutaminase L mediates association with PDZ domain-containing proteins.

Q9QXV0	PCSK1_MOUSE	ProSAAS	10632593	Identification and characterization of proSAAS, a granin-like neuroendocrine peptide precursor that inhibits prohormone processing.

Q63538	MK12_RAT	Mitogen-activated protein kinase 12	10438538	Selective activation of p38alpha and p38gamma by hypoxia. Role in regulation of cyclin D1 by hypoxia in PC12 cells.

P38120	RT09_YEAST	37S ribosomal protein S9, mitochondrial	11278769	Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues.

P25847	MSH2_YEAST	DNA mismatch repair protein MSH2	14562095	Global analysis of protein localization in budding yeast.

P21306	ATP5E_YEAST	ATP synthase subunit epsilon, mitochondrial	1985960	Isolation and complete amino acid sequence of the mitochondrial ATP synthase epsilon-subunit of the yeast Saccharomyces cerevisiae.

C0LGP2	MEE39_ARATH	Probable LRR receptor-like serine/threonine-protein kinase MEE39	15634699	Genetic and molecular identification of genes required for female gametophyte development and function in Arabidopsis.

Q5VT25	MRCKA_HUMAN	Serine/threonine-protein kinase MRCK alpha	9092543	Cloning and chromosomal location of a novel member of the myotonic dystrophy family of protein kinases.

Q9UBQ5	EIF3K_HUMAN	Eukaryotic translation initiation factor 3 subunit K	17322308	Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry.

P51996	YPT32_YEAST	GTP-binding protein YPT32/YPT11	9151665	Two new Ypt GTPases are required for exit from the yeast trans-Golgi compartment.

Q15329	E2F5_HUMAN	Transcription factor E2F5	16360038	Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release.

Q9SB58	ZDH19_ARATH	Probable S-acyltransferase At4g24630	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q9NVM4	ANM7_HUMAN	Protein arginine N-methyltransferase 7	15494416	PRMT7, a new protein arginine methyltransferase that synthesizes symmetric dimethylarginine.

Q9SU08	AUXI1_ARATH	Auxilin-related protein 1	11701884	Role of SH3 domain-containing proteins in clathrin-mediated vesicle trafficking in Arabidopsis.

P07271	PIF1_YEAST	DNA repair and recombination protein PIF1	15907372	Differential involvement of the related DNA helicases Pif1p and Rrm3p in mtDNA point mutagenesis and stability.

Q54EW0	FRMA_DICDI	FERM domain-containing protein A	18349074	The multi-FERM-domain-containing protein FrmA is required for turnover of paxillin-adhesion sites during cell migration of Dictyostelium.

P51965	UB2E1_HUMAN	Ubiquitin-conjugating enzyme E2 E1	16428300	Link between the ubiquitin conjugation system and the ISG15 conjugation system: ISG15 conjugation to the UbcH6 ubiquitin E2 enzyme.

Q13200	PSMD2_HUMAN	26S proteasome non-ATPase regulatory subunit 2	8774743	cDNA cloning and functional analysis of the p97 subunit of the 26S proteasome, a polypeptide identical to the type-1 tumor-necrosis- factor-receptor-associated protein-2/55.11.

P56181	NDUV3_HUMAN	NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial	9344673	Molecular cloning and characterization of the human mitochondrial NADH:oxidoreductase 10-kDa gene (NDUFV3).

O43071	PRP17_SCHPO	Pre-mRNA-processing factor 17	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O95995	GAS8_HUMAN	Growth arrest-specific protein 8	10969087	T lymphocyte-triggering factor of African trypanosomes is associated with the flagellar fraction of the cytoskeleton and represents a new family of proteins that are present in several divergent eukaryotes.

P19425	V15A2_AEDAE	Vitelline membrane protein 15a-2	2394318	Mosquito oostatic factor: a novel decapeptide modulating trypsin-like enzyme biosynthesis in the midgut.

P53723	YN8B_YEAST	UPF0674 endoplasmic reticulum membrane protein YNR021W	14562095	Global analysis of protein localization in budding yeast.

Q9QYN5	BCL10_RAT	B-cell lymphoma/leukemia 10	10753917	Regulatory mechanisms of TRAF2-mediated signal transduction by Bcl10, a MALT lymphoma-associated protein.

P17109	MEND_ECOLI	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase	17760421	Menaquinone biosynthesis in Escherichia coli: identification of 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate as a novel intermediate and re-evaluation of MenD activity.

O14893	GEMI2_HUMAN	Survival of motor neuron protein-interacting protein 1	9323129	The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins.

Q96QD9	UIF_HUMAN	UAP56-interacting factor	19836239	UIF, a new mRNA export adaptor that works together with REF/ALY, requires FACT for recruitment to mRNA.

P61073	CXCR4_HUMAN	C-X-C chemokine receptor type 4	19116316	The E3 ubiquitin ligase atrophin interacting protein 4 binds directly to the chemokine receptor CXCR4 via a novel WW domain-mediated interaction.

Q01546	K22O_HUMAN	Keratin, type II cytoskeletal 2 oral	1282112	Suprabasal marker proteins distinguishing keratinizing squamous epithelia: cytokeratin 2 polypeptides of oral masticatory epithelium and epidermis are different.

P46961	GPI2_YEAST	Phosphatidylinositol N-acetylglucosaminyltransferase GPI2 subunit	15163411	Yeast Ras regulates the complex that catalyzes the first step in GPI- anchor biosynthesis at the ER.

Q7L5Y9	MAEA_HUMAN	Macrophage erythroblast attacher	16510120	Emp is a component of the nuclear matrix of mammalian cells and undergoes dynamic rearrangements during cell division.

Q9ZSZ8	FIP37_ARATH	FKBP12-interacting protein of 37 kDa	9807817	An Arabidopsis immunophilin, AtFKBP12, binds to AtFIP37 (FKBP interacting protein) in an interaction that is disrupted by FK506.

Q6Q595	SCS22_YEAST	Vesicle-associated membrane protein-associated protein SCS22	15668246	A highly conserved binding site in vesicle-associated membrane protein-associated protein (VAP) for the FFAT motif of lipid-binding proteins.

Q23628	LON3_CAEEL	Cuticle collagen lon-3	12019225	Increased or decreased levels of Caenorhabditis elegans lon-3, a gene encoding a collagen, cause reciprocal changes in body length.

Q03652	DML1_YEAST	Protein DML1	14690591	Assigning function to yeast proteins by integration of technologies.

Q10728	MYPT1_RAT	Protein phosphatase 1 regulatory subunit 12A	8543033	Molecular cloning and functional expression of a recombinant 72.5 kDa fragment of the 110 kDa regulatory subunit of smooth muscle protein phosphatase 1M.

O74484	MPG1_SCHPO	Mannose-1-phosphate guanyltransferase	16049679	Mpg1, a fission yeast protein required for proper septum structure, is involved in cell cycle progression through cell-size checkpoint.

Q9NPA2	MMP25_HUMAN	Matrix metalloproteinase-25	11034316	Membrane-type 6 matrix metalloproteinase (MT6-MMP, MMP-25) is the second glycosyl-phosphatidyl inositol (GPI)-anchored MMP.

P40818	UBP8_HUMAN	Ubiquitin carboxyl-terminal hydrolase 8	16520378	The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation.

Q9JI58	RAE1D_MOUSE	Retinoic acid early-inducible protein 1-delta	10894171	Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice.

P85120	DAPLE_XENLA	Daple-like protein	16026968	Novel Daple-like protein positively regulates both the Wnt/beta- catenin pathway and the Wnt/JNK pathway in Xenopus.

Q8CGQ8	NCKX4_MOUSE	Sodium/potassium/calcium exchanger 4	12379639	Molecular cloning of a fourth member of the potassium-dependent sodium-calcium exchanger gene family, NCKX4.

O23680	TOC33_ARATH	Translocase of chloroplast 33, chloroplastic	12869544	Dimerization of Toc-GTPases at the chloroplast protein import machinery.

P40795	FOG_DROME	Protein folded gastrulation	8137424	A putative cell signal encoded by the folded gastrulation gene coordinates cell shape changes during Drosophila gastrulation.

Q9DED4	CIRBB_XENLA	Cold-inducible RNA-binding protein B	16600183	Cold-inducible RNA binding protein is required for the expression of adhesion molecules and embryonic cell movement in Xenopus laevis.

Q15438	CYH1_HUMAN	Cytohesin-1	1511013	Cloning and sequencing of a human cDNA from cytolytic NK/T cells with homology to yeast SEC7.

Q8CFG5	CA2D3_RAT	Voltage-dependent calcium channel subunit alpha-2/delta-3	12606261	Molecular cloning of calcium channel alpha(2)delta-subunits from rat atria and the differential regulation of their expression by IGF-1.

P22725	WNT5A_MOUSE	Protein Wnt-5a	19841259	Reciprocal regulation of Wnt and Gpr177/mouse Wntless is required for embryonic axis formation.

Q9W5P1	MED21_DROME	Mediator of RNA polymerase II transcription subunit 21	12021283	Novel Mediator proteins of the small Mediator complex in Drosophila SL2 cells.

Q7ZY81	NPL1B_XENLA	Nucleosome assembly protein 1-like 1-B	7622566	Members of the NAP/SET family of proteins interact specifically with B-type cyclins.

P14174	MIF_HUMAN	Macrophage migration inhibitory factor	12782713	MIF signal transduction initiated by binding to CD74.

Q9SCT4	IMK2_ARATH	Probably inactive leucine-rich repeat receptor-like protein kinase IMK2	16287169	Arabidopsis cell wall proteome defined using multidimensional protein identification technology.

P70062	T7L1A_XENLA	Transcription factor 7-like 1-A	11238923	Inhibition of Tcf3 binding by I-mfa domain proteins.

P60210	KAX44_TITCA	Potassium channel toxin alpha-KTx 4.4	15025998	Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

P38932	VPS45_YEAST	Vacuolar protein sorting-associated protein 45	7628704	STT10, a novel class-D VPS yeast gene required for osmotic integrity related to the PKC1/STT1 protein kinase pathway.

Q86X76	NIT1_HUMAN	Nitrilase homolog 1	9671749	Nitrilase and Fhit homologs are encoded as fusion proteins in Drosophila melanogaster and Caenorhabditis elegans.

Q7T384	SC5AC_DANRE	Sodium-coupled monocarboxylate transporter 2	17255103	Zebrafish Slc5a12 encodes an electroneutral sodium monocarboxylate transporter (SMCTn). A comparison with the electrogenic SMCT (SMCTe/Slc5a8).

Q641F2	NDR1A_XENLA	Protein NDRG1-A	12943662	Identification and characterization of Xenopus NDRG1.

Q9SWR5	C93C1_SOYBN	2-hydroxyisoflavanone synthase	10375412	Molecular characterization of the enzyme catalyzing the aryl migration reaction of isoflavonoid biosynthesis in soybean.

Q10656	EGL15_CAEEL	Myoblast growth factor receptor egl-15	7585964	An FGF receptor signaling pathway is required for the normal cell migrations of the sex myoblasts in C. elegans hermaphrodites.

Q9BUP3	HTAI2_HUMAN	Oxidoreductase HTATIP2	11313954	Metastasis suppressor CC3 inhibits angiogenic properties of tumor cells in vitro.

Q9LF79	ACA8_ARATH	Calcium-transporting ATPase 8, plasma membrane-type	10938365	At-ACA8 encodes a plasma membrane-localized Ca2+-ATPase of Arabidopsis with a calmodulin-binding domain at the N-terminus.

Q08909	YO385_YEAST	Uncharacterized protein YOR385W	14562095	Global analysis of protein localization in budding yeast.

Q08849	STX3_RAT	Syntaxin-3	7690687	The syntaxin family of vesicular transport receptors.

Q9JIL4	NHRF3_MOUSE	Na(+)/H(+) exchange regulatory cofactor NHE-RF3	14531806	PDZK1: I. a major scaffolder in brush borders of proximal tubular cells.

Q3MHY7	RM10_BOVIN	39S ribosomal protein L10, mitochondrial	11551941	The large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present.

Q16890	TPD53_HUMAN	Tumor protein D53	9484778	Identification of homo- and heteromeric interactions between members of the breast carcinoma-associated D52 protein family using the yeast two-hybrid system.

Q6VVD7	SOX8_XENLA	Transcription factor Sox-8	16943273	Functional analysis of Sox8 during neural crest development in Xenopus.

Q9FR44	PEAM1_ARATH	Phosphoethanolamine N-methyltransferase 1	11115895	The isolation and characterization in yeast of a gene for Arabidopsis S-adenosylmethionine:phospho-ethanolamine N-methyltransferase.

P70552	GFRP_RAT	GTP cyclohydrolase 1 feedback regulatory protein	8702680	Purification and cloning of the GTP cyclohydrolase I feedback regulatory protein, GFRP.

Q9R1M5	NALP5_MOUSE	NACHT, LRR and PYD domains-containing protein 5	14670992	Developmental expression and subcellular localization of mouse MATER, an oocyte-specific protein essential for early development.

Q9LJG3	ESM1_ARATH	GDSL esterase/lipase ESM1	17951448	Proteome analysis of Arabidopsis leaf peroxisomes reveals novel targeting peptides, metabolic pathways, and defense mechanisms.

P0A894	YHBJ_ECOLI	UPF0042 nucleotide-binding protein yhbJ	17824929	Feedback control of glucosamine-6-phosphate synthase GlmS expression depends on the small RNA GlmZ and involves the novel protein YhbJ in Escherichia coli.

Q9VX25	UBE2S_DROME	Ubiquitin-conjugating enzyme E2 S	19822757	Identification of a physiological E2 module for the human anaphase- promoting complex.

Q96J02	ITCH_HUMAN	E3 ubiquitin-protein ligase Itchy homolog	19592251	ITCH K63-ubiquitinates the NOD2 binding protein, RIP2, to influence inflammatory signaling pathways.

Q812E0	CPEB2_MOUSE	Cytoplasmic polyadenylation element-binding protein 2	12672660	CPEB2, a novel putative translational regulator in mouse haploid germ cells.

Q9NRM7	LATS2_HUMAN	Serine/threonine-protein kinase LATS2	12853976	Lats2, a putative tumor suppressor, inhibits G1/S transition.

P0AA41	TRUC_ECOLI	tRNA pseudouridine synthase C	11720289	Identification and site of action of the remaining four putative pseudouridine synthases in Escherichia coli.

Q9QX72	SEBP2_RAT	Selenocysteine insertion sequence-binding protein 2	10637234	A novel RNA binding protein, SBP2, is required for the translation of mammalian selenoprotein mRNAs.

Q9Z340	PARD3_RAT	Partitioning defective 3 homolog	9763423	An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3.

P52785	GUC2E_MOUSE	Guanylyl cyclase GC-E	8838319	Chromosomal localization and genomic organization of genes encoding guanylyl cyclase receptors expressed in olfactory sensory neurons and retina.

P24257	WNT1_DANRE	Protein Wnt-1	12591239	Wnt1 and wnt10b function redundantly at the zebrafish midbrain- hindbrain boundary.

P0A843	TATE_ECOLI	Sec-independent protein translocase protein tatE	9649434	Overlapping functions of components of a bacterial Sec-independent protein export pathway.

Q8RWD9	ACBP5_ARATH	Acyl-CoA-binding domain-containing protein 5	15604682	ACBP4 and ACBP5, novel Arabidopsis acyl-CoA-binding proteins with kelch motifs that bind oleoyl-CoA.

P04817	CAN1_YEAST	Arginine permease	10654085	Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae.

P41411	CDC18_SCHPO	Cell division control protein 18	11988741	Maintenance of replication forks and the S-phase checkpoint by Cdc18p and Orp1p.

Q99497	PARK7_HUMAN	Protein DJ-1	12446870	Mutations in the DJ-1 gene associated with autosomal recessive early- onset Parkinsonism.

Q9USK0	IPK1_SCHPO	Inositol-pentakisphosphate 2-kinase	10960485	Biochemical and functional characterization of inositol 1,3,4,5, 6- pentakisphosphate 2-kinases.

O82291	PAP3_ARATH	Probable plastid-lipid-associated protein 3, chloroplastic	16414959	Tocopherol cyclase (VTE1) localization and vitamin E accumulation in chloroplast plastoglobule lipoprotein particles.

Q9LDL7	PAT1_ARATH	Scarecrow-like transcription factor PAT1	10817761	PAT1, a new member of the GRAS family, is involved in phytochrome A signal transduction.

P03999	OPSB_HUMAN	Blue-sensitive opsin	2937147	Molecular genetics of human color vision: the genes encoding blue, green, and red pigments.

Q9UPP1	PHF8_HUMAN	Histone lysine demethylase PHF8	19843542	PHF8, a gene associated with cleft lip/palate and mental retardation, encodes for an Nepsilon-dimethyl lysine demethylase.

Q9Y738	MIS12_SCHPO	Centromere protein mis12	16079914	Molecular analysis of kinetochore architecture in fission yeast.

Q8INK9	MSRB_DROME	Methionine-R-sulfoxide reductase B1	11929995	Selenoprotein R is a zinc-containing stereo-specific methionine sulfoxide reductase.

P38825	TOM71_YEAST	Protein TOM71	16689936	Integral membrane proteins in the mitochondrial outer membrane of Saccharomyces cerevisiae.

P62308	RUXG_HUMAN	Small nuclear ribonucleoprotein G	12165861	Carcinogenesis and translational controls: TACC1 is down-regulated in human cancers and associates with mRNA regulators.

P29617	PROS_DROME	Homeobox protein prospero	1720353	Prospero is expressed in neuronal precursors and encodes a nuclear protein that is involved in the control of axonal outgrowth in Drosophila.

P84555	TIQ7_RHISA	Kunitz-type serine protease inhibitor RsTIQ7	12941299	Rhipicephalus sanguineus trypsin inhibitors present in the tick larvae: isolation, characterization, and partial primary structure determination.

P51863	VA0D1_MOUSE	V-type proton ATPase subunit d 1	12527205	Diversity of mouse proton-translocating ATPase: presence of multiple isoforms of the C, d and G subunits.

Q9LK31	Y3272_ARATH	Kelch repeat-containing protein At3g27220	16618929	Mapping the Arabidopsis organelle proteome.

O14965	STK6_HUMAN	Serine/threonine-protein kinase 6	9153231	Cell cycle-dependent expression and spindle pole localization of a novel human protein kinase, Aik, related to Aurora of Drosophila and yeast Ipl1.

Q08649	ESA1_YEAST	Histone acetyltransferase ESA1	10911987	Multiple links between the NuA4 histone acetyltransferase complex and epigenetic control of transcription.

Q7TSN2	CLM_MOUSE	CMRF35-like molecule	12893283	Identification and characterization of a new pair of immunoglobulin- like receptors LMIR1 and 2 derived from murine bone marrow-derived mast cells.

O74450	POP3_SCHPO	Ribonucleases P/MRP protein subunit pop3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P46250	SEC14_CANAL	SEC14 cytosolic factor	8896277	Cloning of Candida albicans SEC14 gene homologue coding for a putative essential function.

Q94FB9	AB1D_ARATH	ABC transporter D family member 1	11828016	Ped3p is a peroxisomal ATP-binding cassette transporter that might supply substrates for fatty acid beta-oxidation.

Q94527	NFKB1_DROME	Nuclear factor NF-kappa-B p110 subunit	10619029	Relish, a central factor in the control of humoral, but not cellular immunity in Drosophila.

Q9Y2Y4	ZBT32_HUMAN	Zinc finger and BTB domain-containing protein 32	10572087	A novel BTB/POZ transcriptional repressor protein interacts with the Fanconi anemia group C protein and PLZF.

Q9LMA8	TI10A_ARATH	Protein TIFY 10A	20360743	NINJA connects the co-repressor TOPLESS to jasmonate signalling.

P42858	HD_HUMAN	Huntingtin	8696339	Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract.

P49407	ARRB1_HUMAN	Beta-arrestin-1	19363159	Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2.

P49762	DOA_DROME	Serine/threonine-protein kinase Doa	7926721	The Doa locus encodes a member of a new protein kinase family and is essential for eye and embryonic development in Drosophila melanogaster.

Q9U7C9	NUCMR_DICDI	Nucleomorphin	15896312	An N-terminal nuclear localization sequence but not the calmodulin- binding domain mediates nuclear localization of nucleomorphin, a protein that regulates nuclear number in Dictyostelium.

Q9Y7J6	PPK21_SCHPO	Serine/threonine-protein kinase ppk21	15821139	Systematic deletion analysis of fission yeast protein kinases.

Q9NL83	ORCKA_PROCL	Orcokinin peptides type A	10753578	Identification of orcokinin gene-related peptides in the brain of the crayfish Procambarus clarkii by the combination of MALDI-TOF and on- line capillary HPLC/Q-Tof mass spectrometries and molecular cloning.

P42847	RT18_YEAST	37S ribosomal protein S18, mitochondrial	9151978	Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae.

O88291	ZN326_MOUSE	Zinc finger protein 326	10798446	Characterization of a zinc finger protein ZAN75: nuclear localization signal, transcriptional activator activity, and expression during neuronal differentiation of P19 cells.

Q9HDV4	LID2_SCHPO	Lid2 complex component lid2	12488447	High conservation of the Set1/Rad6 axis of histone 3 lysine 4 methylation in budding and fission yeasts.

P78396	CCNA1_HUMAN	Cyclin-A1	9041194	Characterization of a second human cyclin A that is highly expressed in testis and in several leukemic cell lines.

Q9SAR1	MADS8_ORYSJ	MADS-box transcription factor 8	12395189	Ovule-specific MADS-box proteins have conserved protein-protein interactions in monocot and dicot plants.

Q8IMQ6	GR97A_DROME	Putative gustatory receptor 97a	10710312	Candidate taste receptors in Drosophila.

P01583	IL1A_HUMAN	Interleukin-1 alpha	2989698	Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs.

O88935	SYN1_MOUSE	Synapsin-1	11571277	PrPC directly interacts with proteins involved in signaling pathways.

Q98SP8	EPABA_XENLA	Embryonic polyadenylate-binding protein A	16001084	The DAZL family proteins are PABP-binding proteins that regulate translation in germ cells.

P97353	SEC1_MOUSE	Galactoside 2-alpha-L-fucosyltransferase 3	11323419	Molecular cloning, genomic mapping, and expression of two secretor blood group alpha (1,2)fucosyltransferase genes differentially regulated in mouse uterine epithelium and gastrointestinal tract.

Q8WXS5	CCG8_HUMAN	Voltage-dependent calcium channel gamma-8 subunit	11170751	A cluster of three novel Ca(2+) channel gamma subunit genes on chromosome 19q13.4: evolution and expression profile of the gamma subunit gene family.

Q80U72	SCRIB_MOUSE	Protein scribble homolog	12499390	Disruption of scribble (Scrb1) causes severe neural tube defects in the circletail mouse.

O43086	ELG1_SCHPO	Telomere length regulation protein elg1	16040599	Contrasting effects of Elg1-RFC and Ctf18-RFC inactivation in the absence of fully functional RFC in fission yeast.

P70452	STX4_MOUSE	Syntaxin-4	19033398	DOC2B: a novel syntaxin-4 binding protein mediating insulin-regulated GLUT4 vesicle fusion in adipocytes.

P22760	AAAD_HUMAN	Arylacetamide deacetylase	17936933	Human carboxylesterases and their role in xenobiotic and endobiotic metabolism.

Q03785	VHS1_YEAST	Serine/threonine-protein kinase VHS1	14562095	Global analysis of protein localization in budding yeast.

Q2YFS2	PILRB_MOUSE	Paired immunoglobulin-like type 2 receptor beta	14970179	Activation of natural killer cells and dendritic cells upon recognition of a novel CD99-like ligand by paired immunoglobulin-like type 2 receptor.

P43586	LOC1_YEAST	60S ribosomal subunit assembly/export protein LOC1	11583614	Composition and functional characterization of yeast 66S ribosome assembly intermediates.

O74628	YQ53_SCHPO	Uncharacterized oxidoreductase C162.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9P7L7	YOS6_SCHPO	Uncharacterized membrane protein C21C3.06	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O08601	MTP_MOUSE	Microsomal triglyceride transfer protein large subunit	10713055	A deficiency of microsomal triglyceride transfer protein reduces apolipoprotein B secretion.

Q13625	ASPP2_HUMAN	Apoptosis-stimulating of p53 protein 2	19377511	The DEAD box protein Ddx42p modulates the function of ASPP2, a stimulator of apoptosis.

O76038	SEGN_HUMAN	Secretagogin	10811645	Cloning and expression of secretagogin, a novel neuroendocrine- and pancreatic islet of Langerhans-specific Ca2+-binding protein.

Q15637	SF01_HUMAN	Splicing factor 1	8752089	Mammalian splicing factor SF1 is encoded by variant cDNAs and binds to RNA.

Q14C87	T132D_HUMAN	Transmembrane protein 132D	12966072	Molecular cloning of a novel transmembrane protein MOLT expressed by mature oligodendrocytes.

Q6IUP1	SOLH1_MOUSE	Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1	16564520	Sohlh1 is essential for spermatogonial differentiation.

Q07075	AMPE_HUMAN	Glutamyl aminopeptidase	8346219	Molecular cloning of the human kidney differentiation antigen gp160: human aminopeptidase A.

P08913	ADA2A_HUMAN	Alpha-2A adrenergic receptor	10948191	An Asn to Lys polymorphism in the third intracellular loop of the human alpha 2A-adrenergic receptor imparts enhanced agonist-promoted Gi coupling.

Q9UP79	ATS8_HUMAN	A disintegrin and metalloproteinase with thrombospondin motifs 8	10610729	ADAM-TS8, a novel metalloprotease of the ADAM-TS family located on mouse chromosome 9 and human chromosome 11.

Q5B7R2	CELB_EMENI	Endo-beta-1,4-glucanase celB	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

Q6X5Y6	WRI1_ARATH	Ethylene-responsive transcription factor WRI1	15500472	WRINKLED1 encodes an AP2/EREB domain protein involved in the control of storage compound biosynthesis in Arabidopsis.

O13282	TAF5_SCHPO	Transcription initiation factor TFIID subunit 5	11972332	Identification of histone H4-like TAF in Schizosaccharomyces pombe as a protein that interacts with WD repeat-containing TAF.

Q9CAF2	NUD26_ARATH	Nudix hydrolase 26, chloroplastic	18815383	Molecular characterization of organelle-type Nudix hydrolases in Arabidopsis.

Q86YT5	S13A5_HUMAN	Solute carrier family 13 member 5	12445824	Human Na+ -coupled citrate transporter: primary structure, genomic organization, and transport function.

P25573	MGR1_YEAST	Mitochondrial inner membrane i-AAA protease supercomplex subunit MGR1	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q9Y676	RT18B_HUMAN	28S ribosomal protein S18b, mitochondrial	11279123	The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present.

P82965	ADFA_TENMO	Antidiuretic factor A	11756661	Identification of a potent antidiuretic factor acting on beetle Malpighian tubules.

O14285	SPC34_SCHPO	DASH complex subunit spc34	16079914	Molecular analysis of kinetochore architecture in fission yeast.

P48578	PP2A3_ARATH	Serine/threonine-protein phosphatase PP2A-3 catalytic subunit	7948902	Molecular characterization of a fourth isoform of the catalytic subunit of protein phosphatase 2A from Arabidopsis thaliana.

O60245	PCDH7_HUMAN	Protocadherin-7	9615233	Cloning, expression analysis, and chromosomal localization of BH- protocadherin (PCDH7), a novel member of the cadherin superfamily.

Q9SXZ2	FT_ARATH	Protein FLOWERING LOCUS T	10583960	A pair of related genes with antagonistic roles in mediating flowering signals.

Q9GZV9	FGF23_HUMAN	Fibroblast growth factor 23	15040831	FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis.

P32363	GPI3_YEAST	Phosphatidylinositol N-acetylglucosaminyltransferase GPI3 subunit	10970797	Photoaffinity labelling with P3-(4-azidoanilido)uridine 5'- triphosphate identifies gpi3p as the UDP-GlcNAc-binding subunit of the enzyme that catalyses formation of GlcNAc-phosphatidylinositol, the first glycolipid intermediate in glycosylphosphatidylinositol synthesis.

Q64249	NR6A1_MOUSE	Nuclear receptor subfamily 6 group A member 1	7854358	Cloning of a novel orphan receptor (GCNF) expressed during germ cell development.

O14336	MUG80_SCHPO	Meiotically up-regulated gene 80 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O42877	FCF2_SCHPO	rRNA-processing protein fcf2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q800K6	TOB1A_XENLA	DNA topoisomerase 2-binding protein 1-A	15960976	Initiation of DNA replication requires the RECQL4 protein mutated in Rothmund-Thomson syndrome.

O95479	G6PE_HUMAN	GDH/6PGL endoplasmic bifunctional protein	10349511	Human hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) encoded at 1p36: coding sequence and expression.

P32435	MFAL2_YEAST	Mating factor alpha-2	6306574	Saccharomyces cerevisiae contains two discrete genes coding for the alpha-factor pheromone.

Q06850	CDPK1_ARATH	Calcium-dependent protein kinase 1	12913141	Subcellular targeting of nine calcium-dependent protein kinase isoforms from Arabidopsis.

Q9EP97	SENP3_MOUSE	Sentrin-specific protease 3	11029585	A novel mammalian Smt3-specific isopeptidase 1 (SMT3IP1) localized in the nucleolus at interphase.

Q22258	ATR_CAEEL	Serine/threonine-protein kinase ATR	16319925	Distinct modes of ATR activation after replication stress and DNA double-strand breaks in Caenorhabditis elegans.

P52011	CYP3_CAEEL	Peptidyl-prolyl cis-trans isomerase 3	8694762	Cloning and biochemical characterization of the cyclophilin homologues from the free-living nematode Caenorhabditis elegans.

D2XNQ9	FLOT2_MEDTR	Flotillin-like protein 2	20018678	Plant flotillins are required for infection by nitrogen-fixing bacteria.

Q59E36	RCOR_DROME	REST corepressor	15306652	A conserved role but different partners for the transcriptional corepressor CoREST in fly and mammalian nervous system formation.

P59220	CALM7_ARATH	Calmodulin-7	11855649	Characterization of three new members of the Arabidopsis thaliana calmodulin gene family: conserved and highly diverged members of the gene family functionally complement a yeast calmodulin null.

Q6UXN9	WDR82_HUMAN	WD repeat-containing protein 82	17355966	Identification and characterization of the human Set1B histone H3- Lys4 methyltransferase complex.

Q9S7I6	RPK2_ARATH	LRR receptor-like serine/threonine-protein kinase RPK2	18158146	Two receptor-like kinases required together for the establishment of Arabidopsis cotyledon primordia.

P83403	CEC_GLOMM	Cecropin	11886771	Immunopeptides in the defense reactions of Glossina morsitans to bacterial and Trypanosoma brucei brucei infections.

P23847	DPPA_ECOLI	Periplasmic dipeptide transport protein	1702779	Identification and characterization of dppA, an Escherichia coli gene encoding a periplasmic dipeptide transport protein.

Q8T626	DLT_DROME	Protein disks lost	14667407	The Drosophila cell survival gene discs lost encodes a cytoplasmic Codanin-1-like protein, not a homolog of tight junction PDZ protein Patj.

Q15119	PDK2_HUMAN	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial	7499431	Diversity of the pyruvate dehydrogenase kinase gene family in humans.

P38251	RFC5_YEAST	Replication factor C subunit 5	8559655	Identification of the fifth subunit of Saccharomyces cerevisiae replication factor C.

P24470	CP2CN_RAT	Cytochrome P450 2C23	8514789	Molecular cloning, expression, and enzymatic characterization of the rat kidney cytochrome P-450 arachidonic acid epoxygenase.

Q9YHE8	T7L1A_DANRE	Transcription factor 7-like 1-A	11057671	Repressor activity of Headless/Tcf3 is essential for vertebrate head formation.

Q12059	ULA1_YEAST	NEDD8-activating enzyme E1 regulatory subunit	9531531	Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex.

P18537	FRIZ_DROME	Frizzled	2174014	Molecular structure of frizzled, a Drosophila tissue polarity gene.

Q9ULZ2	STAP1_HUMAN	Signal-transducing adaptor protein 1	10518561	Molecular cloning of a docking protein, BRDG1, that acts downstream of the Tec tyrosine kinase.

P17255	VATA_YEAST	V-type proton ATPase catalytic subunit A	8508780	Protein splicing of the yeast TFP1 intervening protein sequence: a model for self-excision.

P38713	OSH3_YEAST	Oxysterol-binding protein homolog 3	11408574	Dual targeting of Osh1p, a yeast homologue of oxysterol-binding protein, to both the Golgi and the nucleus-vacuole junction.

P62158	CALM_HUMAN	Calmodulin	16760425	CP110 cooperates with two calcium-binding proteins to regulate cytokinesis and genome stability.

Q53080	PSA1_RHOER	Proteasome subunit alpha 1	16843899	Proteasome assembly triggers a switch required for active-site maturation.

Q9D2A5	CR3L4_MOUSE	Cyclic AMP-responsive element-binding protein 3-like protein 4	16107712	Reduction of spermatogenesis but not fertility in Creb3l4-deficient mice.

P47120	DOHH_YEAST	Deoxyhypusine hydroxylase	14562095	Global analysis of protein localization in budding yeast.

Q9P7S9	YIF4_SCHPO	Uncharacterized protein C23G3.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O94439	YFI5_SCHPO	FAS1 domain-containing protein C22H12.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P60880	SNP25_HUMAN	Synaptosomal-associated protein 25	8760387	Insulin-responsive tissues contain the core complex protein SNAP-25 (synaptosomal-associated protein 25) A and B isoforms in addition to syntaxin 4 and synaptobrevins 1 and 2.

P23337	GYS1_YEAST	Glycogen [starch] synthase isoform 1	2123485	Isolation of the GSY1 gene encoding yeast glycogen synthase and evidence for the existence of a second gene.

P34092	MYOB_DICDI	Myosin IB heavy chain	8609164	Dictyostelium mutants lacking multiple classic myosin I isoforms reveal combinations of shared and distinct functions.

Q00168	KCC2A_DROME	Calcium/calmodulin-dependent protein kinase type II alpha chain	1910789	The alpha subunit of type II Ca2+/calmodulin-dependent protein kinase is highly conserved in Drosophila.

P32790	SLA1_YEAST	Actin cytoskeleton-regulatory complex protein SLA1	10594004	Pan1p, End3p, and Sla1p, three yeast proteins required for normal cortical actin cytoskeleton organization, associate with each other and play essential roles in cell wall morphogenesis.

Q14541	HNF4G_HUMAN	Hepatocyte nuclear factor 4-gamma	8622695	Human hepatocyte nuclear factor 4 isoforms are encoded by distinct and differentially expressed genes.

B2RU80	PTPRB_MOUSE	Receptor-type tyrosine-protein phosphatase beta	19451274	VE-PTP controls blood vessel development by balancing Tie-2 activity.

Q90WN4	FOXD2_XENLA	Forkhead box protein D2	15656969	Of fox and frogs: fox (fork head/winged helix) transcription factors in Xenopus development.

P49747	COMP_HUMAN	Cartilage oligomeric matrix protein	7670472	Pseudoachondroplasia and multiple epiphyseal dysplasia due to mutations in the cartilage oligomeric matrix protein gene.

P46963	CTK3_YEAST	CTD kinase subunit gamma	7565723	The yeast carboxyl-terminal repeat domain kinase CTDK-I is a divergent cyclin-cyclin-dependent kinase complex.

P14678	RSMB_HUMAN	Small nuclear ribonucleoprotein-associated proteins B and B'	11574479	Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein.

P20435	RPAB2_YEAST	DNA-directed RNA polymerases I, II, and III subunit RPABC2	2186966	Subunits shared by eukaryotic nuclear RNA polymerases.

Q9I8A3	HEY1_XENLA	Hairy/enhancer-of-split related with YRPW motif protein 1	15531363	Sequences downstream of the bHLH domain of the Xenopus hairy-related transcription factor-1 act as an extended dimerization domain that contributes to the selection of the partners.

P62841	RS15_HUMAN	40S ribosomal protein S15	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

P84841	ES1B_RANSA	Esculentin-1B	16394170	Skin secretions of Rana saharica frogs reveal antimicrobial peptides esculentins-1 and -1B and brevinins-1E and -2EC with novel insulin releasing activity.

Q9P6S5	ASK1_SCHPO	DASH complex subunit ask1	16079914	Molecular analysis of kinetochore architecture in fission yeast.

P97846	CNTP1_RAT	Contactin-associated protein 1	9118959	Identification of a novel contactin-associated transmembrane receptor with multiple domains implicated in protein-protein interactions.

Q8K4B0	MTA1_MOUSE	Metastasis-associated protein MTA1	11483358	Differential expression and subcellular distribution of the mouse metastasis-associated proteins Mta1 and Mta3.

O74384	ERFB_SCHPO	Palmitoyltransferase erf2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P27540	ARNT_HUMAN	Aryl hydrocarbon receptor nuclear translocator	10395741	Interactions of nuclear receptor coactivator/corepressor proteins with the aryl hydrocarbon receptor complex.

Q8NIL3	AES1_SCHPO	Antisense-enhancing sequence 1	12034844	Dominant genetic screen for cofactors that enhance antisense RNA- mediated gene silencing in fission yeast.

P22265	TSH_DROME	Protein teashirt	8951796	The Drosophila teashirt homeotic protein is a DNA-binding protein and modulo, a HOM-C regulated modifier of variegation, is a likely candidate for being a direct target gene.

Q9S7D9	ACCR1_ARATH	Serine/threonine-protein kinase-like protein CCR1	15549374	Molecular analysis of the CRINKLY4 gene family in Arabidopsis thaliana.

P0A6M2	DSBB_ECOLI	Disulfide bond formation protein B	8430071	A pathway for disulfide bond formation in vivo.

P0AEU7	SKP_ECOLI	Chaperone protein skp	11278858	The early interaction of the outer membrane protein phoE with the periplasmic chaperone Skp occurs at the cytoplasmic membrane.

P00957	SYA_ECOLI	Alanyl-tRNA synthetase	1712632	Evidence for a 'cysteine-histidine box' metal-binding site in an Escherichia coli aminoacyl-tRNA synthetase.

Q3E7A8	YN162_YEAST	Uncharacterized protein YNL162W-A	14562095	Global analysis of protein localization in budding yeast.

O46203	A32CD_DROME	Accessory gland protein Acp32CD	9474779	New genes for male accessory gland proteins in Drosophila melanogaster.

B7ZSG3	WT1A_XENLA	Wilms tumor protein homolog A	16574097	Evi1 is specifically expressed in the distal tubule and duct of the Xenopus pronephros and plays a role in its formation.

Q11184	LE756_CAEEL	Protein let-756	16672054	Direct and heterologous approaches to identify the LET-756/FGF interactome.

O00124	UBXN8_HUMAN	UBX domain-containing protein 8	9027507	Cloning and characterization of Rep-8 (D8S2298E) in the human chromosome 8p11.2-p12.

P55853	SUMO_CAEEL	Small ubiquitin-related modifier	15990876	Chromatin regulation and sumoylation in the inhibition of Ras-induced vulval development in Caenorhabditis elegans.

Q96LC9	BMF_HUMAN	Bcl-2-modifying factor	11546872	Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis.

O14064	BIR1_SCHPO	Protein bir1	10571085	S. pombe Pbh1p: an inhibitor of apoptosis domain containing protein is essential for chromosome segregation.

Q8NFH4	NUP37_HUMAN	Nucleoporin Nup37	17360435	Cell-cycle-dependent phosphorylation of the nuclear pore Nup107-160 subcomplex.

P00850	ATP6_DROME	ATP synthase subunit a	6408489	Drosophila melanogaster mitochondrial DNA, a novel organization and genetic code.

Q67Y93	KRP1_ARATH	Cyclin-dependent kinase inhibitor 1	15749764	Novel functions of plant cyclin-dependent kinase inhibitors, ICK1/KRP1, can act non-cell-autonomously and inhibit entry into mitosis.

P52824	DGKQ_HUMAN	Diacylglycerol kinase theta	10066731	Diacylglycerol kinase theta binds to and is negatively regulated by active RhoA.

Q03088	SVL3_YEAST	Styryl dye vacuolar localization protein 3	9751732	Isolation of yeast mutants defective for localization of vacuolar vital dyes.

Q09768	GSH1_SCHPO	Glutamate--cysteine ligase	8619315	Gcs1, a gene encoding gamma-glutamylcysteine synthetase in the fission yeast Schizosaccharomyces pombe.

Q9U8Q4	PRSN_PIERA	Pierisin	10485873	Molecular cloning of an apoptosis-inducing protein, pierisin, from cabbage butterfly: possible involvement of ADP-ribosylation in its activity.

P62320	SMD3_MOUSE	Small nuclear ribonucleoprotein Sm D3	19470752	Three proteins of the U7-specific Sm ring function as the molecular ruler to determine the site of 3'-end processing in mammalian histone pre-mRNA.

Q08605	GAGA_DROME	Transcription factor GAGA	11256608	The GAGA factor of Drosophila interacts with SAP18, a Sin3-associated polypeptide.

Q06102	YTH1_YEAST	mRNA 3'-end-processing protein YTH1	12626716	Functional dissection of the zinc finger and flanking domains of the Yth1 cleavage/polyadenylation factor.

P19075	TSN8_HUMAN	Tetraspanin-8	2395876	Molecular cloning of cDNA for the human tumor-associated antigen CO- 029 and identification of related transmembrane antigens.

P16949	STMN1_HUMAN	Stathmin	10675326	Op18/stathmin caps a kinked protofilament-like tubulin tetramer.

Q6PBM1	GLRX5_DANRE	Glutaredoxin-related protein 5, mitochondrial	16110529	Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis.

P35731	FABG_YEAST	3-oxoacyl-[acyl-carrier-protein] reductase	9388293	Two genes of the putative mitochondrial fatty acid synthase in the genome of Saccharomyces cerevisiae.

O75569	PRKRA_HUMAN	Interferon-inducible double stranded RNA-dependent protein kinase activator A	9687506	PACT, a protein activator of the interferon-induced protein kinase, PKR.

P08575	PTPRC_HUMAN	Receptor-type tyrosine-protein phosphatase C	2956090	Structural variants of human T200 glycoprotein (leukocyte-common antigen).

Q9H944	MED20_HUMAN	Mediator of RNA polymerase II transcription subunit 20	9933582	The human homologue of Drosophila TRF-proximal protein is associated with an RNA polymerase II-SRB complex.

Q4Z8K6	RBP9X_DROME	Ran-binding proteins 9/10 homolog	16055650	Genome-wide RNAi analysis of JAK/STAT signaling components in Drosophila.

P17255	VATA_YEAST	V-type proton ATPase catalytic subunit A	11283612	Skp1 forms multiple protein complexes, including RAVE, a regulator of V-ATPase assembly.

Q57X81	JBP2_TRYBB	Bifunctional helicase and thymine dioxygenase JBP2	15694344	Regulation of trypanosome DNA glycosylation by a SWI2/SNF2-like protein.

Q9JL19	NCOA6_MOUSE	Nuclear receptor coactivator 6	10681503	Cloning and characterization of RAP250, a nuclear receptor coactivator.

P48001	KNAT4_ARATH	Homeobox protein knotted-1-like 4	8980519	Three knotted1-like homeobox genes in Arabidopsis.

Q04931	SSRP1_RAT	FACT complex subunit SSRP1	8464746	Rat and chick cDNA clones encoding HMG-like proteins.

Q1PFR7	LEC2_ARATH	B3 domain-containing transcription factor LEC2	18287041	Arabidopsis LEAFY COTYLEDON2 induces maturation traits and auxin activity: implications for somatic embryogenesis.

O75912	DGKI_HUMAN	Diacylglycerol kinase iota	9830018	The cloning and characterization of a novel human diacylglycerol kinase, DGK-iota.

O95544	NADK_HUMAN	NAD kinase	11594753	Structural and functional characterization of human NAD kinase.

P38913	FAD1_YEAST	FAD synthase	7799934	Cloning and characterization of FAD1, the structural gene for flavin adenine dinucleotide synthetase of Saccharomyces cerevisiae.

Q90259	ASL1A_DANRE	Achaete-scute homolog 1a	16481349	The proneural gene ascl1a is required for endocrine differentiation and cell survival in the zebrafish adenohypophysis.

Q95Q17	MED7_CAEEL	Mediator of RNA polymerase II transcription subunit 7	11728440	The MED-7 transcriptional mediator encoded by let-49 is required for gonad and germ cell development in Caenorhabditis elegans.

P08761	MSRA_DROME	Peptide methionine sulfoxide reductase	12145281	Reaction mechanism, evolutionary analysis, and role of zinc in Drosophila methionine-R-sulfoxide reductase.

Q9SY55	ECA3_ARATH	Calcium-transporting ATPase 3, endoplasmic reticulum-type	18567829	A distinct endosomal Ca2+/Mn2+ pump affects root growth through the secretory process.

Q09669	ADH4_SCHPO	Alcohol dehydrogenase 4	18203864	Response of Schizosaccharomyces pombe to zinc deficiency.

P29456	IL10_RAT	Interleukin-10	8484757	Molecular cloning of rat cytokine synthesis inhibitory factor (IL-10) cDNA and expression in spleen and macrophages.

Q12341	HAT1_YEAST	Histone acetyltransferase type B catalytic subunit	14761951	Hif1 is a component of yeast histone acetyltransferase B, a complex mainly localized in the nucleus.

O94772	LY6H_HUMAN	Lymphocyte antigen 6H	9799603	Isolation and characterization of a new member of the human Ly6 gene family (LY6H).

Q90Z12	HES4A_XENLA	Transcription factor HES-4-A	18710660	Hairy2 functions through both DNA-binding and non DNA-binding mechanisms at the neural plate border in Xenopus.

Q12734	CSR2_YEAST	Transcription factor CSR2	10679005	Sbe2p and sbe22p, two homologous Golgi proteins involved in yeast cell wall formation.

Q9Y5P4	C43BP_HUMAN	Collagen type IV alpha-3-binding protein	10212244	Characterization of a novel type of serine/threonine kinase that specifically phosphorylates the human goodpasture antigen.

P46972	IMP2_YEAST	Mitochondrial inner membrane protease subunit 2	8132591	Purified inner membrane protease I of yeast mitochondria is a heterodimer.

Q18801	GMD1_CAEEL	GDP-mannose 4,6 dehydratase 1	10924467	Bacillus thuringiensis (Bt) toxin susceptibility and isolation of resistance mutants in the nematode Caenorhabditis elegans.

Q12125	GET4_YEAST	Golgi to ER traffic protein 4	19325107	Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum.

Q07084	SSK1_YEAST	Osomolarity two-component system protein SSK1	8808622	Yeast HOG1 MAP kinase cascade is regulated by a multistep phosphorelay mechanism in the SLN1-YPD1-SSK1 two-component osmosensor.

Q9NVN3	RIC8B_HUMAN	Synembryn-B	12652642	Human brain synembryn interacts with Gsalpha and Gqalpha and is translocated to the plasma membrane in response to isoproterenol and carbachol.

P86287	ACT1_PLAFX	Actin-1	15670824	Unusual properties of Plasmodium falciparum actin: new insights into microfilament dynamics of apicomplexan parasites.

Q5U430	UBR3_MOUSE	E3 ubiquitin-protein ligase UBR3	17462990	Biochemical and genetic studies of UBR3, a ubiquitin ligase with a function in olfactory and other sensory systems.

Q06504	NAT3_YEAST	N-terminal acetyltransferase B complex catalytic subunit NAT3	14562095	Global analysis of protein localization in budding yeast.

Q63246	FOXC2_RAT	Forkhead box protein C2	7683413	Identification of nine tissue-specific transcription factors of the hepatocyte nuclear factor 3/forkhead DNA-binding-domain family.

P43234	CATO_HUMAN	Cathepsin O	7929457	Human cathepsin O. Molecular cloning from a breast carcinoma, production of the active enzyme in Escherichia coli, and expression analysis in human tissues.

Q91ZW3	SMCA5_MOUSE	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5	11980720	WSTF-ISWI chromatin remodeling complex targets heterochromatic replication foci.

P06780	RHO1_YEAST	GTP-binding protein RHO1	12660244	Gbetagamma recruits Rho1 to the site of polarized growth during mating in budding yeast.

Q9GN62	PAR4_CAEEL	Serine/threonine-protein kinase par-4	3345562	Identification of genes required for cytoplasmic localization in early C. elegans embryos.

Q9NQ92	COPR5_HUMAN	Cooperator of PRMT5	18404153	The histone-binding protein COPR5 is required for nuclear functions of the protein arginine methyltransferase PRMT5.

Q8L8Q7	COBL2_ARATH	COBRA-like protein 2	12376623	The COBRA family of putative GPI-anchored proteins in Arabidopsis. A new fellowship in expansion.

Q60793	KLF4_MOUSE	Krueppel-like factor 4	17060454	Conditional deletion of the mouse Klf4 gene results in corneal epithelial fragility, stromal edema, and loss of conjunctival goblet cells.

B3DK56	PTPRU_DANRE	Receptor-type tyrosine-protein phosphatase U	15226256	Receptor tyrosine phosphatase psi is required for delta/notch signalling and cyclic gene expression in the presomitic mesoderm.

Q9XYT4	ORCH_ORCCA	Orchestin	12560077	Phosphorylation of serine residues is fundamental for the calcium- binding ability of orchestin, a soluble matrix protein from crustacean calcium storage structures.

P39726	GCSH_YEAST	Glycine cleavage system H protein, mitochondrial	9020168	Molecular characterization of GCV3, the Saccharomyces cerevisiae gene coding for the glycine cleavage system hydrogen carrier protein.

O60701	UGDH_HUMAN	UDP-glucose 6-dehydrogenase	9737970	Molecular cloning and characterization of the human and mouse UDP- glucose dehydrogenase genes.

P78549	NTHL1_HUMAN	Endonuclease III-like protein 1	8990169	Cloning and characterization of a functional human homolog of Escherichia coli endonuclease III.

Q12165	ATPD_YEAST	ATP synthase subunit delta, mitochondrial	8026496	ATP synthase of yeast mitochondria. Isolation of the F1 delta subunit, sequence and disruption of the structural gene.

Q9UQ88	CD11A_HUMAN	Cell division protein kinase 11A	9750192	Duplication of a genomic region containing the Cdc2L1-2 and MMP21-22 genes on human chromosome 1p36.3 and their linkage to D1Z2.

Q9ULC4	MCTS1_HUMAN	Malignant T cell-amplified sequence 1	9766643	A novel candidate oncogene, MCT-1, is involved in cell cycle progression.

O14640	DVL1_HUMAN	Segment polarity protein dishevelled homolog DVL-1	11742073	beta-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins.

Q16206	ENOX2_HUMAN	Ecto-NOX disulfide-thiol exchanger 2	8150545	Molecular cloning and expression of a cDNA encoding a protein detected by the K1 antibody from an ovarian carcinoma (OVCAR-3) cell line.

O14830	PPE2_HUMAN	Serine/threonine-protein phosphatase with EF-hands 2	9326663	Identification and characterization of a conserved family of protein serine/threonine phosphatases homologous to Drosophila retinal degeneration C.

P40847	SAP1_SCHPO	Switch-activating protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q03774	TRM82_YEAST	tRNA (guanine-N(7)-)-methyltransferase subunit TRM82	14562095	Global analysis of protein localization in budding yeast.

P01130	LDLR_HUMAN	Low-density lipoprotein receptor	12221107	ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2.

Q9Y7Y0	YGR8_SCHPO	Uncharacterized derlin-like protein C365.08c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O43248	HXC11_HUMAN	Homeobox protein Hox-C11	9582375	The HOXC11 homeodomain protein interacts with the lactase-phlorizin hydrolase promoter and stimulates HNF1alpha-dependent transcription.

Q94AG2	SERK1_ARATH	Somatic embryogenesis receptor kinase 1	16473966	The Arabidopsis SOMATIC EMBRYOGENESIS RECEPTOR-LIKE KINASE1 protein complex includes BRASSINOSTEROID-INSENSITIVE1.

O14490	DLGP1_HUMAN	Disks large-associated protein 1	9286858	DAP-1, a novel protein that interacts with the guanylate kinase-like domains of hDLG and PSD-95.

Q42384	PRL1_ARATH	Protein pleiotropic regulatory locus 1	17575050	Regulation of plant innate immunity by three proteins in a complex conserved across the plant and animal kingdoms.

O88491	NSD1_MOUSE	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific	12805229	NSD1 is essential for early post-implantation development and has a catalytically active SET domain.

Q8TAQ2	SMRC2_HUMAN	SWI/SNF complex subunit SMARCC2	11018012	Functional selectivity of recombinant mammalian SWI/SNF subunits.

P39106	MNN1_YEAST	Alpha-1,3-mannosyltransferase MNN1	8146181	Cloning and analysis of the Saccharomyces cerevisiae MNN9 and MNN1 genes required for complex glycosylation of secreted proteins.

P53924	DMA2_YEAST	E3 ubiquitin-protein ligase DMA2	14562095	Global analysis of protein localization in budding yeast.

P38117	ETFB_HUMAN	Electron transfer flavoprotein subunit beta	7912128	Mutations and polymorphisms of the gene encoding the beta-subunit of the electron transfer flavoprotein in three patients with glutaric acidemia type II.

O45523	RGS10_CAEEL	Regulator of G-protein signaling rgs-10	15687288	New genes with roles in the C. elegans embryo revealed using RNAi of ovary-enriched ORFeome clones.

Q8K467	TMIE_MOUSE	Transmembrane inner ear expressed protein	12140191	Mutation of the novel gene Tmie results in sensory cell defects in the inner ear of spinner, a mouse model of human hearing loss DFNB6.

Q9GZY0	NXF2_HUMAN	Nuclear RNA export factor 2	11073998	TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture.

Q64735	CRRY_MOUSE	Complement regulatory protein Crry	10642554	A critical role for murine complement regulator crry in fetomaternal tolerance.

P53920	NM111_YEAST	Pro-apoptotic serine protease NMA111	14562095	Global analysis of protein localization in budding yeast.

Q62048	PEA15_MOUSE	Astrocytic phosphoprotein PEA-15	10588860	The phosphoprotein protein PEA-15 inhibits Fas- but increases TNF-R1- mediated caspase-8 activity and apoptosis.

O75832	PSD10_HUMAN	26S proteasome non-ATPase regulatory subunit 10	10613832	Reduced stability of retinoblastoma protein by gankyrin, an oncogenic ankyrin-repeat protein overexpressed in hepatomas.

Q16854	DGUOK_HUMAN	Deoxyguanosine kinase, mitochondrial	8692979	Cloning and expression of human deoxyguanosine kinase cDNA.

Q22036	CAN5_CAEEL	Calpain-5	10783162	Proteolysis in Caenorhabditis elegans sex determination: cleavage of TRA-2A by TRA-3.

Q80UJ1	S22AK_MOUSE	Solute carrier family 22 member 20	15369770	Identification of a novel murine organic anion transporter family member, OAT6, expressed in olfactory mucosa.

P49419	AL7A1_HUMAN	Alpha-aminoadipic semialdehyde dehydrogenase	9417906	An ancient conserved gene expressed in the human inner ear: identification, expression analysis, and chromosomal mapping of human and mouse antiquitin (ATQ1).

Q155U0	FFR_DANRE	Protein fat-free	16581006	Zebrafish fat-free is required for intestinal lipid absorption and Golgi apparatus structure.

P79937	MEIS1_XENLA	Homeobox protein Meis1	16631621	Pbx1 and Meis1 regulate activity of the Xenopus laevis Zic3 promoter through a highly conserved region.

Q925J9	MED1_MOUSE	Mediator of RNA polymerase II transcription subunit 1	14500757	The thyroid hormone receptor-associated protein TRAP220 is required at distinct embryonic stages in placental, cardiac, and hepatic development.

P04211	LV001_HUMAN	Ig lambda chain V region 4A	6091030	The isolation of a human Ig V lambda gene from a recombinant library of chromosome 22 and estimation of its copy number.

Q96FV9	THOC1_HUMAN	THO complex subunit 1	10512864	Apoptosis induced by the nuclear death domain protein p84N5 is inhibited by association with Rb protein.

Q9NZS2	KLRF1_HUMAN	Killer cell lectin-like receptor subfamily F member 1	10671213	Human KLRF1, a novel member of the killer cell lectin-like receptor gene family: molecular characterization, genomic structure, physical mapping to the NK gene complex and expression analysis.

O81902	PUB8_ARATH	U-box domain-containing protein 8	17412590	A cryptic modifier causing transient self-incompatibility in Arabidopsis thaliana.

Q62936	DLG3_RAT	Disks large homolog 3	9115257	SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density.

P81943	ALL5_APIGR	Allergen Api g 5	10718855	N-terminal sequences of high molecular weight allergens from celery tuber.

Q93W95	PMTD_ARATH	Probable methyltransferase PMT13	16618929	Mapping the Arabidopsis organelle proteome.

P09615	WNTG_DROME	Protein wingless	15166250	Drosophila wnt-1 undergoes a hydrophobic modification and is targeted to lipid rafts, a process that requires porcupine.

Q9Y4A5	TRRAP_HUMAN	Transformation/transcription domain-associated protein	18206972	A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing.

Q8ZQC8	SOPD2_SALTY	Secreted effector protein sopD2	15554961	The related effector proteins SopD and SopD2 from Salmonella enterica serovar Typhimurium contribute to virulence during systemic infection of mice.

Q9UTB5	PSD1_SCHPO	Phosphatidylserine decarboxylase proenzyme 1, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P26196	DDX6_HUMAN	Probable ATP-dependent RNA helicase DDX6	1394235	The RCK gene associated with t(11;14) translocation is distinct from the MLL/ALL-1 gene with t(4;11) and t(11;19) translocations.

P32468	CDC12_YEAST	Cell division control protein 12	8791410	The septins: roles in cytokinesis and other processes.

Q02336	ADA2_YEAST	Transcriptional adapter 2	10490601	The ADA complex is a distinct histone acetyltransferase complex in Saccharomyces cerevisiae.

P41889	CUT9_SCHPO	Anaphase-promoting complex subunit cut9	7798319	Bypassing anaphase by fission yeast cut9 mutation: requirement of cut9+ to initiate anaphase.

O43291	SPIT2_HUMAN	Kunitz-type protease inhibitor 2	9434156	Cloning of a new Kunitz-type protease inhibitor with a putative transmembrane domain overexpressed in pancreatic cancer.

P54787	VPS9_YEAST	Vacuolar protein sorting-associated protein 9	12628920	A ubiquitin-binding motif required for intramolecular monoubiquitylation, the CUE domain.

Q9Y4P1	ATG4B_HUMAN	Cysteine protease ATG4B	12446702	Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy.

Q08920	NCBP2_YEAST	Nuclear cap-binding protein subunit 2	8682299	The yeast splicing factor Mud13p is a commitment complex component and corresponds to CBP20, the small subunit of the nuclear cap-binding complex.

Q03557	GATH_YEAST	Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q9NRR8	C42S1_HUMAN	CDC42 small effector protein 1	10816584	SPECs, small binding proteins for Cdc42.

Q14155	ARHG7_HUMAN	Rho guanine nucleotide exchange factor 7	19041750	Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma.

Q9D8I1	PERP1_MOUSE	Plasma cell-induced resident endoplasmic reticulum protein	19805157	pERp1 is significantly up-regulated during plasma cell differentiation and contributes to the oxidative folding of immunoglobulin.

Q7TMA4	GP120_MOUSE	G-protein coupled receptor 120	15619630	Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120.

P02599	CALM_DICDI	Calmodulin	14595117	DWWA, a novel protein containing two WW domains and an IQ motif, is required for scission of the residual cytoplasmic bridge during cytokinesis in Dictyostelium.

Q99MD9	NASP_MOUSE	Nuclear autoantigenic sperm protein	10893414	Characterization of the histone H1-binding protein, NASP, as a cell cycle-regulated somatic protein.

O14100	ZDS1_SCHPO	Protein zds1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O95154	ARK73_HUMAN	Aflatoxin B1 aldehyde reductase member 3	10383892	cDNA cloning, expression and activity of a second human aflatoxin B1- metabolizing member of the aldo-keto reductase superfamily, AKR7A3.

Q6QNI4	C71AJ_AMMMJ	Psoralen synthase	17068340	Molecular cloning and functional characterization of psoralen synthase, the first committed monooxygenase of furanocoumarin biosynthesis.

Q9C0W3	YHI4_SCHPO	Uncharacterized membrane protein P22H7.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P10363	PRI1_YEAST	DNA primase small subunit	3061469	The yeast DNA polymerase-primase complex: genes and proteins.

Q9YH12	LSM14_PLEWA	Protein LSM14 homolog	9851867	Identification of a novel mRNA-associated protein in oocytes of Pleurodeles waltl and Xenopus laevis.

Q03112	EVI1_HUMAN	MDS1 and EVI1 complex locus protein EVI1	10856240	The evi-1 oncoprotein inhibits c-Jun N-terminal kinase and prevents stress-induced cell death.

Q9D975	SRXN1_MOUSE	Sulfiredoxin-1	15448164	Characterization of mammalian sulfiredoxin and its reactivation of hyperoxidized peroxiredoxin through reduction of cysteine sulfinic acid in the active site to cysteine.

Q8L4H0	WEE1_ARATH	Wee1-like protein kinase	17209125	Arabidopsis WEE1 kinase controls cell cycle arrest in response to activation of the DNA integrity checkpoint.

P26343	DAL80_YEAST	Nitrogen regulatory protein DAL80	1944286	Expression of the DAL80 gene, whose product is homologous to the GATA factors and is a negative regulator of multiple nitrogen catabolic genes in Saccharomyces cerevisiae, is sensitive to nitrogen catabolite repression.

O60704	TPST2_HUMAN	Protein-tyrosine sulfotransferase 2	9733778	Molecular cloning and expression of human and mouse tyrosylprotein sulfotransferase-2 and a tyrosylprotein sulfotransferase homologue in Caenorhabditis elegans.

Q9SL15	GRP3_ARATH	Glycine-rich protein 3	2152168	Differential expression of five Arabidopsis genes encoding glycine- rich proteins.

P11831	SRF_HUMAN	Serum response factor	19350017	SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta1-integrin.

Q9NTK5	OLA1_HUMAN	Obg-like ATPase 1	17430889	Human OLA1 defines an ATPase subfamily in the Obg family of GTP- binding proteins.

Q12852	M3K12_HUMAN	Mitogen-activated protein kinase kinase kinase 12	14697235	SP3 acts as a positive regulator on the core promoter of human ZPK gene.

P12398	HSP77_YEAST	Heat shock protein SSC1, mitochondrial	10779357	Role of the mitochondrial Hsp70s, Ssc1 and Ssq1, in the maturation of Yfh1.

O15304	SIVA_HUMAN	Apoptosis regulatory protein Siva	9177220	CD27, a member of the tumor necrosis factor receptor family, induces apoptosis and binds to Siva, a proapoptotic protein.

Q9ZTC3	MYB90_ARATH	Transcription factor MYB90	15361138	Comprehensive identification of Arabidopsis thaliana MYB transcription factors interacting with R/B-like BHLH proteins.

O16850	FOXO_CAEEL	Forkhead box protein O	11747825	daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans.

Q9UQ84	EXO1_HUMAN	Exonuclease 1	14636568	Mechanism of 5'-directed excision in human mismatch repair.

Q8R4S8	CRLF2_RAT	Cytokine receptor-like factor 2	11891057	Cloning of rat thymic stromal lymphopoietin receptor (TSLPR) and characterization of genomic structure of murine Tslpr gene.

C0LQF3	SCRA2_ARALY	Defensin-like SRCA-homolog protein	19300485	Independent S-locus mutations caused self-fertility in Arabidopsis thaliana.

Q8R4D5	TRPM8_MOUSE	Transient receptor potential cation channel subfamily M member 8	11893340	A TRP channel that senses cold stimuli and menthol.

Q9M9Y4	DRIP1_ARATH	E3 ubiquitin protein ligase DRIP1	18552202	Arabidopsis DREB2A-interacting proteins function as RING E3 ligases and negatively regulate plant drought stress-responsive gene expression.

P60891	PRPS1_HUMAN	Ribose-phosphate pyrophosphokinase 1	17701896	Arts syndrome is caused by loss-of-function mutations in PRPS1.

Q8NBS3	S4A11_HUMAN	Sodium bicarbonate transporter-like protein 11	15525507	NaBC1 is a ubiquitous electrogenic Na+-coupled borate transporter essential for cellular boron homeostasis and cell growth and proliferation.

Q66GI9	ANTR4_ARATH	Probable anion transporter 4, chloroplastic	18086223	Functional analysis of the Arabidopsis PHT4 family of intracellular phosphate transporters.

Q07878	VPS13_YEAST	Vacuolar protein sorting-associated protein 13	9265642	Novel genes involved in endosomal traffic in yeast revealed by suppression of a targeting-defective plasma membrane ATPase mutant.

Q54N00	FORH_DICDI	Formin-H	16675552	The bundling activity of vasodilator-stimulated phosphoprotein is required for filopodium formation.

O23403	PPD1_ARATH	PsbP domain-containing protein 1, chloroplastic	11719511	Proteome map of the chloroplast lumen of Arabidopsis thaliana.

O08934	UNC4_MOUSE	Homeobox protein unc-4 homolog	10804168	Uncx4.1 is required for the formation of the pedicles and proximal ribs and acts upstream of Pax9.

O54329	LANA_STRMU	Lantibiotic mutacin-2	16626493	Mutacin H-29B is identical to mutacin II (J-T8).

P18496	ATP10_YEAST	Mitochondrial ATPase complex subunit ATP10	2141026	ATP 10, a yeast nuclear gene required for the assembly of the mitochondrial F1-F0 complex.

Q3LGD4	RFP4A_DANRE	Rab11 family-interacting protein 4A	16457799	Rab11-FIP4 is predominantly expressed in neural tissues and involved in proliferation as well as in differentiation during zebrafish retinal development.

Q9P6J7	YHD3_SCHPO	Uncharacterized MFS-type transporter C1683.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P32943	CGS6_YEAST	S-phase entry cyclin-6	8319908	CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae.

P84854	RIPL2_PHYDI	Ribosome-inactivating protein PD-L3/PD-L4	10213004	Isolation and characterization of four type-1 ribosome-inactivating proteins, with polynucleotide:adenosine glycosidase activity, from leaves of Phytolacca dioica L.

Q8PDA8	T23O_XANCP	Tryptophan 2,3-dioxygenase	18783250	Histidine 55 of tryptophan 2,3-dioxygenase is not an active site base but regulates catalysis by controlling substrate binding.

P00944	XYLA_ECOLI	Xylose isomerase	6325179	Molecular cloning, DNA structure and expression of the Escherichia coli D-xylose isomerase.

P23301	IF5A1_YEAST	Eukaryotic translation initiation factor 5A-1	19424157	Hypusine-containing protein eIF5A promotes translation elongation.

P01358	GAJU_HUMAN	Gastric juice peptide 1	5538385	Peptides of normal human gastric juice.

P55053	FABP5_RAT	Fatty acid-binding protein, epidermal	8166694	Molecular cloning of a cDNA encoding a novel fatty acid-binding protein from rat skin.

Q9LIR6	BAM1_ARATH	Beta-amylase 1, chloroplastic	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

P36591	DYR_SCHPO	Dihydrofolate reductase	8088538	The isolation and characterization of the gene (dfr1) encoding dihydrofolate reductase (DHFR) in Schizosaccharomyces pombe.

Q80Z19	MUC2_MOUSE	Mucin-2	18806221	The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria.

Q10668	SWI2_SCHPO	Mating-type switching protein swi2	14663140	Two different Swi5-containing protein complexes are involved in mating-type switching and recombination repair in fission yeast.

B2RU80	PTPRB_MOUSE	Receptor-type tyrosine-protein phosphatase beta	12234928	VE-PTP and VE-cadherin ectodomains interact to facilitate regulation of phosphorylation and cell contacts.

Q62141	SIN3B_MOUSE	Paired amphipathic helix protein Sin3b	20170641	RNF220, an E3 ubiquitin ligase that targets Sin3B for ubiquitination.

Q00869	ESYN_FUSEQ	Enniatin synthase	8483420	Molecular characterization of the enniatin synthetase gene encoding a multifunctional enzyme catalysing N-methyldepsipeptide formation in Fusarium scirpi.

Q9ER69	FL2D_MOUSE	Pre-mRNA-splicing regulator WTAP	11001926	Identification of WTAP, a novel Wilms' tumour 1-associating protein.

Q9QZS0	CO4A3_MOUSE	Collagen alpha-3(IV) chain	12842087	Physiological levels of tumstatin, a fragment of collagen IV alpha3 chain, are generated by MMP-9 proteolysis and suppress angiogenesis via alphaV beta3 integrin.

Q925H0	ACCN1_MOUSE	Amiloride-sensitive cation channel 1, neuronal	9368048	A modulatory subunit of acid sensing ion channels in brain and dorsal root ganglion cells.

Q8CJ99	SCLT1_RAT	Sodium channel and clathrin linker 1	15797711	CAP-1A is a novel linker that binds clathrin and the voltage-gated sodium channel Na(v)1.8.

P23193	TCEA1_HUMAN	Transcription elongation factor A protein 1	1708494	Cloning, expression and characterization of the human transcription elongation factor, TFIIS.

Q3V6T2	GRDN_HUMAN	Girdin	16139227	Akt/PKB regulates actin organization and cell motility via Girdin/APE.

P0AFI2	PARC_ECOLI	DNA topoisomerase 4 subunit A	8227000	Escherichia coli topoisomerase IV. Purification, characterization, subunit structure, and subunit interactions.

P21583	SCF_HUMAN	Kit ligand	10049787	Parathyroid hormone-regulated production of stem cell factor in human osteoblasts and osteoblast-like cells.

Q64143	P55G_MOUSE	Phosphatidylinositol 3-kinase regulatory subunit gamma	7542745	The structure and function of p55PIK reveal a new regulatory subunit for phosphatidylinositol 3-kinase.

P05388	RLA0_HUMAN	60S acidic ribosomal protein P0	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

O75342	LX12B_HUMAN	Arachidonate 12-lipoxygenase, 12R-type	9618483	A 12R-lipoxygenase in human skin: mechanistic evidence, molecular cloning, and expression.

Q9EQQ0	SUV92_MOUSE	Histone-lysine N-methyltransferase SUV39H2	11094092	Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression.

Q3USQ7	TM90A_MOUSE	Capucin	16359841	Capucin: a novel striatal marker down-regulated in rodent models of Huntington disease.

Q04637	IF4G1_HUMAN	Eukaryotic translation initiation factor 4 gamma 1	10996799	Interaction of eIF4G with poly(A)-binding protein stimulates translation and is critical for Xenopus oocyte maturation.

Q8LK56	DME_ARATH	Transcriptional activator DEMETER	16624880	DEMETER and REPRESSOR OF SILENCING 1 encode 5-methylcytosine DNA glycosylases.

Q5FVE4	ACBG2_HUMAN	Long-chain-fatty-acid--CoA ligase ACSBG2	16762313	A novel mammalian bubblegum-related acyl-CoA synthetase restricted to testes and possibly involved in spermatogenesis.

Q06649	3BP2_MOUSE	SH3 domain-binding protein 2	8438166	Identification of a ten-amino acid proline-rich SH3 binding site.

P80511	S10AC_HUMAN	Protein S100-A12	11522286	Calcitermin, a novel antimicrobial peptide isolated from human airway secretions.

P07483	FABPH_RAT	Fatty acid-binding protein, heart	3036869	Analysis of the tissue-specific expression, developmental regulation, and linkage relationships of a rodent gene encoding heart fatty acid binding protein.

Q92636	FAN_HUMAN	Protein FAN	8808629	FAN, a novel WD-repeat protein, couples the p55 TNF-receptor to neutral sphingomyelinase.

P48567	PUS4_YEAST	tRNA pseudouridine synthase 4	9358157	The yeast gene YNL292w encodes a pseudouridine synthase (Pus4) catalyzing the formation of psi55 in both mitochondrial and cytoplasmic tRNAs.

O13684	PCS1_SCHPO	Chromosome segregation protein pcs1	12689592	Kinetochore recruitment of two nucleolar proteins is required for homolog segregation in meiosis I.

Q7ZXB1	MCM7B_XENLA	DNA replication licensing factor mcm7-B	9214647	Licensing of DNA replication by a multi-protein complex of MCM/P1 proteins in Xenopus eggs.

P33176	KINH_HUMAN	Kinesin-1 heavy chain	1607388	Cloning and expression of a human kinesin heavy chain gene: interaction of the COOH-terminal domain with cytoplasmic microtubules in transfected CV-1 cells.

P26039	TLN1_MOUSE	Talin-1	15272303	Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle.

Q9C6B8	PINI_ARATH	Auxin efflux carrier component 1	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q93ZD7	MRS24_ARATH	Magnesium transporter MRS2-4	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

O17580	NOC2L_CAEEL	Nucleolar complex protein 2 homolog	16876152	Alterations in ribosome biogenesis cause specific defects in C. elegans hermaphrodite gonadogenesis.

P36553	HEM6_ECOLI	Coproporphyrinogen-III oxidase, aerobic	8300522	Isolation of the hemF operon containing the gene for the Escherichia coli aerobic coproporphyrinogen III oxidase by in vivo complementation of a yeast HEM13 mutant.

P36601	RAD51_SCHPO	DNA repair protein rhp51	14663140	Two different Swi5-containing protein complexes are involved in mating-type switching and recombination repair in fission yeast.

O81445	CNBL1_ARATH	Calcineurin B-like protein 1	12194854	A calcium sensor and its interacting protein kinase are global regulators of abscisic acid signaling in Arabidopsis.

P38308	CS111_YEAST	F-box protein COS111	12661761	The possible mechanism of action of ciclopirox olamine in the yeast Saccharomyces cerevisiae.

P83171	GNK1_GINBI	Antifungal protein ginkbilobin-1	11118300	Ginkbilobin, a novel antifungal protein from Ginkgo biloba seeds with sequence similarity to embryo-abundant protein.

P40217	EIF3I_YEAST	Eukaryotic translation initiation factor 3 subunit I	9671501	Identification of a translation initiation factor 3 (eIF3) core complex, conserved in yeast and mammals, that interacts with eIF5.

P06802	ENPP1_MOUSE	Ectonucleotide pyrophosphatase/phosphodiesterase family member 1	8223581	Identification and characterization of a soluble form of the plasma cell membrane glycoprotein PC-1 (5'-nucleotide phosphodiesterase).

P22543	VPS34_YEAST	Phosphatidylinositol 3-kinase VPS34	11157979	Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae.

O58035	SYA_PYRHO	Alanyl-tRNA synthetase	16087889	Molecular basis of alanine discrimination in editing site.

P38326	SWC5_YEAST	SWR1-complex protein 5	14690608	A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1.

Q99788	CML1_HUMAN	Chemokine-like receptor 1	9144535	A novel G protein-coupled receptor with homology to neuropeptide and chemoattractant receptors expressed during bone development.

P30926	ACHB4_HUMAN	Neuronal acetylcholine receptor subunit beta-4	1330682	Neuronal-type nicotinic receptors in human neuroblastoma and small- cell lung carcinoma cell lines.

Q06224	YSH1_YEAST	Endoribonuclease YSH1	15037765	Evidence that polyadenylation factor CPSF-73 is the mRNA 3' processing endonuclease.

P25653	FIG2_YEAST	Factor-induced gene 2 protein	9456310	Pheromone-regulated genes required for yeast mating differentiation.

Q13322	GRB10_HUMAN	Growth factor receptor-bound protein 10	17376403	GRB10 binds to LRP6, the Wnt co-receptor and inhibits canonical Wnt signaling pathway.

P62258	1433E_HUMAN	14-3-3 protein epsilon	7644510	14-3-3 proteins associate with cdc25 phosphatases.

Q61045	SIM1_MOUSE	Single-minded homolog 1	8927054	Two new members of the murine Sim gene family are transcriptional repressors and show different expression patterns during mouse embryogenesis.

O14064	BIR1_SCHPO	Protein bir1	16199877	Suppressors of Bir1p (Survivin) identify roles for the chromosomal passenger protein Pic1p (INCENP) and the replication initiation factor Psf2p in chromosome segregation.

Q08562	ULS1_YEAST	ATP-dependent helicase ULS1	17728242	Ubiquitin-dependent proteolytic control of SUMO conjugates.

O94756	MEU14_SCHPO	Meiotic expression up-regulated protein 14	12759375	Fission yeast meu14+ is required for proper nuclear division and accurate forespore membrane formation during meiosis II.

P02724	GLPA_HUMAN	Glycophorin-A	8245024	Alteration of splice site selection by an exon mutation in the human glycophorin A gene.

Q7SIC1	FUCL_ANGAN	Fucolectin	12091873	A novel fucose recognition fold involved in innate immunity.

Q04744	EMX2_MOUSE	Homeobox protein EMX2	15147765	Emx1 and Emx2 cooperate in initial phase of archipallium development.

Q14686	NCOA6_HUMAN	Nuclear receptor coactivator 6	10866662	A new family of nuclear receptor coregulators that integrates nuclear receptor signaling through CBP.

Q9P4W7	APC5_SCHPO	Anaphase-promoting complex subunit 5	12477395	Proteomics analysis identifies new components of the fission and budding yeast anaphase-promoting complexes.

Q9NPB9	CCRL1_HUMAN	C-C chemokine receptor type 11	10767544	Cloning of CCRL1, an orphan seven transmembrane receptor related to chemokine receptors, expressed abundantly in the heart.

P49368	TCPG_HUMAN	T-complex protein 1 subunit gamma	8001976	Assignment of the human homologue of the mTRiC-P5 gene (TRIC5) to band 1q23 by fluorescence in situ hybridization.

Q8L3W1	VRN1_ARATH	B3 domain-containing transcription factor VRN1	12114624	Multiple roles of Arabidopsis VRN1 in vernalization and flowering time control.

Q16206	ENOX2_HUMAN	Ecto-NOX disulfide-thiol exchanger 2	11888291	Molecular cloning and characterization of a tumor-associated, growth- related, and time-keeping hydroquinone (NADH) oxidase (tNOX) of the HeLa cell surface.

Q9NYJ8	TAB2_HUMAN	TGF-beta-activated kinase 1 and MAP3K7-binding protein 2	19935683	Two-sided ubiquitin binding explains specificity of the TAB2 NZF domain.

Q12753	HAA1_YEAST	Transcriptional activator HAA1	11504737	Haa1, a protein homologous to the copper-regulated transcription factor ace1, is a novel transcriptional activator.

Q86WB7	UN93A_HUMAN	Protein unc-93 homolog A	12381271	The human homologue of unc-93 maps to chromosome 6q27 - characterisation and analysis in sporadic epithelial ovarian cancer.

Q9XFH9	TRXF2_ARATH	Thioredoxin F2, chloroplastic	19259774	A novel extended family of stromal thioredoxins.

Q76LX8	ATS13_HUMAN	A disintegrin and metalloproteinase with thrombospondin motifs 13	11557746	Structure of von Willebrand factor-cleaving protease (ADAMTS13), a metalloprotease involved in thrombotic thrombocytopenic purpura.

Q38951	2AAG_ARATH	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A gamma isoform	7811971	Characterisation of cDNA and genomic clones encoding homologues of the 65 kDa regulatory subunit of protein phosphatase 2A in Arabidopsis thaliana.

P26449	BUB3_YEAST	Cell cycle arrest protein BUB3	11726501	Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores.

P49961	ENTP1_HUMAN	Ectonucleoside triphosphate diphosphohydrolase 1	7930580	The CD39 lymphoid cell activation antigen. Molecular cloning and structural characterization.

P16473	TSHR_HUMAN	Thyrotropin receptor	7920658	Germline mutations in the thyrotropin receptor gene cause non- autoimmune autosomal dominant hyperthyroidism.

P26436	ASPX_HUMAN	Acrosomal protein SP-10	1693291	Cloning and sequencing of cDNAs coding for the human intra-acrosomal antigen SP-10.

Q9XWD6	CED1_CAEEL	Cell death abnormality protein 1	1936965	Genes required for the engulfment of cell corpses during programmed cell death in Caenorhabditis elegans.

P25929	NPY1R_HUMAN	Neuropeptide Y receptor type 1	1317848	Cloning and functional expression of a human neuropeptide Y/peptide YY receptor of the Y1 type.

Q10067	ORC3_SCHPO	Origin recognition complex subunit 3	10535928	Identification and reconstitution of the origin recognition complex from Schizosaccharomyces pombe.

Q9BQI3	E2AK1_HUMAN	Eukaryotic translation initiation factor 2-alpha kinase 1	11036079	Hsp90 regulates p50(cdc37) function during the biogenesis of the active conformation of the heme-regulated eIF2 alpha kinase.

Q01329	PTA1_YEAST	Pre-tRNA-processing protein PTA1	1508188	PTA1, an essential gene of Saccharomyces cerevisiae affecting pre- tRNA processing.

Q9R5C6	LC3_BACSU	Antibacterial protein LC3	1295599	Purification and partial characterization of an antibacterial protein LCIII.

P0A6Z1	HSCA_ECOLI	Chaperone protein hscA	7665466	Hsc66, an Hsp70 homolog in Escherichia coli, is induced by cold shock but not by heat shock.

P12270	TPR_HUMAN	Nucleoprotein TPR	18981471	Tpr directly binds to Mad1 and Mad2 and is important for the Mad1- Mad2-mediated mitotic spindle checkpoint.

Q9HGP9	YM03_SCHPO	Uncharacterized protein C212.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q03048	COFI_YEAST	Cofilin	8440472	Isolation of a yeast essential gene, COF1, that encodes a homologue of mammalian cofilin, a low-M(r) actin-binding and depolymerizing protein.

P84382	XT2_XENTR	Antimicrobial peptide 2	11738090	Antimicrobial peptides isolated from skin secretions of the diploid frog, Xenopus tropicalis (Pipidae).

P40348	RFC2_YEAST	Replication factor C subunit 2	10660302	A novel Rad24 checkpoint protein complex closely related to replication factor C.

Q23628	LON3_CAEEL	Cuticle collagen lon-3	12524338	A cuticle collagen encoded by the lon-3 gene may be a target of TGF- beta signaling in determining Caenorhabditis elegans body shape.

Q13075	BIRC1_HUMAN	Baculoviral IAP repeat-containing protein 1	7813013	The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy.

P15808	THY1_DICDI	Probable thymidylate synthase thy1	2813371	Molecular complementation of a genetic marker in Dictyostelium using a genomic DNA library.

Q94AR8	LEUC_ARATH	3-isopropylmalate dehydratase	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q20390	PPT1_CAEEL	Palmitoyl-protein thioesterase 1	15672447	Identification and characterization of Caenorhabditis elegans palmitoyl protein thioesterase1.

Q9N4M4	ANC1_CAEEL	Nuclear anchorage protein 1	12169658	Role of ANC-1 in tethering nuclei to the actin cytoskeleton.

Q13761	RUNX3_HUMAN	Runt-related transcription factor 3	7835892	AML1, AML2, and AML3, the human members of the runt domain gene- family: cDNA structure, expression, and chromosomal localization.

P23321	PSBO1_ARATH	Oxygen-evolving enhancer protein 1-1, chloroplastic	15722336	The manganese-stabilizing protein is required for photosystem II assembly/stability and photoautotrophy in higher plants.

P57721	PCBP3_HUMAN	Poly(rC)-binding protein 3	10936052	Identification of two novel mammalian genes establishes a subfamily of KH-domain RNA-binding proteins.

Q9FDW1	MYB44_ARATH	Transcription factor MYB44	16463103	The MYB transcription factor superfamily of Arabidopsis: expression analysis and phylogenetic comparison with the rice MYB family.

Q9GLG4	SCG1_PIG	Secretogranin-1	11168356	Identification and characterization of novel chromogranin B-derived peptides from porcine chromaffin granules by liquid chromatography/electrospray tandem MS.

O13902	DAK1_SCHPO	Dihydroxyacetone kinase 1	10091325	Cloning and overexpression in Escherichia coli of the gene encoding dihydroxyacetone kinase isoenzyme I from Schizosaccharomyces pombe, and its application to dihydroxyacetone phosphate production.

P38820	UBA4_YEAST	Adenylyltransferase and sulfurtransferase UBA4	19151091	Mechanistic characterization of the sulfur-relay system for eukaryotic 2-thiouridine biogenesis at tRNA wobble positions.

Q9HGM9	DNJC7_SCHPO	DnaJ homolog subfamily C member 7 homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P22791	HMCS2_RAT	Hydroxymethylglutaryl-CoA synthase, mitochondrial	1971108	Rat mitochondrial and cytosolic 3-hydroxy-3-methylglutaryl-CoA synthases are encoded by two different genes.

P53692	SMC6_SCHPO	Structural maintenance of chromosomes protein 6	16478984	The Nse5-Nse6 dimer mediates DNA repair roles of the Smc5-Smc6 complex.

P48524	BUL1_YEAST	Ubiquitin ligase-binding protein BUL1	8668140	Bul1, a new protein that binds to the Rsp5 ubiquitin ligase in Saccharomyces cerevisiae.

Q8WYJ6	SEPT1_HUMAN	Septin-1	16179162	Septin1, a new interaction partner for human serine/threonine kinase aurora-B.

Q9QXE4	T53I1_MOUSE	Tumor protein p53-inducible nuclear protein 1	11557757	Molecular and functional characterization of the stress-induced protein (SIP) gene and its two transcripts generated by alternative splicing. SIP induced by stress and promotes cell death.

P18289	JRA_DROME	Transcription factor AP-1	2116361	The Drosophila Fos-related AP-1 protein is a developmentally regulated transcription factor.

Q42371	ERECT_ARATH	LRR receptor-like serine/threonine-protein kinase ERECTA	19589071	The ERECTA receptor-like kinase regulates cell wall-mediated resistance to pathogens in Arabidopsis thaliana.

O88643	PAK1_MOUSE	Serine/threonine-protein kinase PAK 1	18716323	Scrib regulates PAK activity during the cell migration process.

Q62315	JARD2_MOUSE	Protein Jumonji	20064375	Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells.

Q8WSR7	CTNB_DICDI	Countin-2	11737154	Two cell-counting factors regulate the aggregate size of the cellular slime mold Dictyostelium discoideum.

P31044	PEBP1_RAT	Phosphatidylethanolamine-binding protein 1	10622376	Hippocampal cholinergic neurostimulating peptides (HCNP).

Q9FGM0	FTSHB_ARATH	ATP-dependent zinc metalloprotease FTSH 11, chloroplastic/mitochondrial	16157880	AtFtsH6 is involved in the degradation of the light-harvesting complex II during high-light acclimation and senescence.

Q9NVM4	ANM7_HUMAN	Protein arginine N-methyltransferase 7	19110445	Accurate localization and relative quantification of arginine methylation using nanoflow liquid chromatography coupled to electron transfer dissociation and orbitrap mass spectrometry.

P35189	TAF14_YEAST	Transcription initiation factor TFIID subunit 14	10788514	Identification of two novel TAF subunits of the yeast Saccharomyces cerevisiae TFIID complex.

Q38872	CDPK6_ARATH	Calcium-dependent protein kinase 6	12068094	Calcium signaling through protein kinases. The Arabidopsis calcium- dependent protein kinase gene family.

Q69Z98	BRSK2_MOUSE	BR serine/threonine-protein kinase 2	15705853	Mammalian SAD kinases are required for neuronal polarization.

Q8C878	UBA3_MOUSE	NEDD8-activating enzyme E1 catalytic subunit	11696557	The NEDD8 system is essential for cell cycle progression and morphogenetic pathway in mice.

P40359	PSF2_YEAST	DNA replication complex GINS protein PSF2	12730134	GINS, a novel multiprotein complex required for chromosomal DNA replication in budding yeast.

Q9Y345	SC6A5_HUMAN	Sodium- and chloride-dependent glycine transporter 2	9845349	Molecular cloning and functional expression of the human glycine transporter GlyT2 and chromosomal localisation of the gene in the human genome.

Q9LJG3	ESM1_ARATH	GDSL esterase/lipase ESM1	16679459	The gene controlling the quantitative trait locus EPITHIOSPECIFIER MODIFIER1 alters glucosinolate hydrolysis and insect resistance in Arabidopsis.

Q09765	UBA3_SCHPO	NEDD8-activating enzyme E1 catalytic subunit	14623327	But1 and But2 proteins bind to Uba3, a catalytic subunit of E1 for neddylation, in fission yeast.

Q24318	TFDP_DROME	Transcription factor Dp	15479636	Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes.

P40507	AIR1_YEAST	Protein AIR1	15935759	Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase.

Q75I94	BGL08_ORYSJ	Beta-glucosidase 8	19766588	Rice family GH1 glycoside hydrolases with beta-D-glucosidase and beta-D-mannosidase activities.

P01717	LV403_HUMAN	Ig lambda chain V-IV region Hil	418804	Amino acid sequence of the variable region of the light (lambda) chain from human myeloma cryoimmunoglobulin IgG Hil.

Q5MJ70	SPDYA_HUMAN	Speedy protein A	11980914	Human Speedy: a novel cell cycle regulator that enhances proliferation through activation of Cdk2.

Q7CFU4	SLYD_YERPE	FKBP-type peptidyl-prolyl cis-trans isomerase slyD	16388577	SlyD proteins from different species exhibit high prolyl isomerase and chaperone activities.

P53905	LSM7_YEAST	U6 snRNA-associated Sm-like protein LSm7	10747033	A Sm-like protein complex that participates in mRNA degradation.

Q8NI77	KI18A_HUMAN	Kinesin-like protein KIF18A	17346968	The human kinesin Kif18A is a motile microtubule depolymerase essential for chromosome congression.

Q945K7	IDH5_ARATH	Isocitrate dehydrogenase [NAD] catalytic subunit 5, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

O74808	CLR1_SCHPO	Cryptic loci regulator protein 1	17289569	SHREC, an effector complex for heterochromatic transcriptional silencing.

P02751	FINC_HUMAN	Fibronectin	12225811	Matrix-matrix interaction of cartilage oligomeric matrix protein and fibronectin.

Q5A1D5	SPT16_CANAL	FACT complex subunit SPT16	12420162	Validation of Cdc68p as a novel antifungal target.

Q7RTX0	TS1R3_HUMAN	Taste receptor type 1 member 3	15299024	The cysteine-rich region of T1R3 determines responses to intensely sweet proteins.

Q9SIS3	MA656_ARATH	65-kDa microtubule-associated protein 6	19060108	The C-terminal variable region specifies the dynamic properties of Arabidopsis microtubule-associated protein MAP65 isotypes.

Q9IAV3	HHEX_DANRE	Hematopoietically-expressed homeobox protein hhex	10531010	A role for the extraembryonic yolk syncytial layer in patterning the zebrafish embryo suggested by properties of the hex gene.

Q39214	RPM1_ARATH	Disease resistance protein RPM1	12062092	An evolutionarily conserved mediator of plant disease resistance gene function is required for normal Arabidopsis development.

Q80XB4	NRAP_MOUSE	Nebulin-related-anchoring protein	15765519	N-RAP expression during mouse heart development.

Q6GLC9	FMR1_XENTR	Fragile X mental retardation protein 1 homolog	15968590	Two members of the Fxr gene family, Fmr1 and Fxr1, are differentially expressed in Xenopus tropicalis.

P49858	CNI_DROME	Protein cornichon	7540118	Cornichon and the EGF receptor signaling process are necessary for both anterior-posterior and dorsal-ventral pattern formation in Drosophila.

A6NKF1	SAC31_HUMAN	SAC3 domain-containing protein 1	16239144	Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.

Q8CFC2	MYT1_MOUSE	Myelin transcription factor 1	9373037	Myelin transcription factor 1 (Myt1) of the oligodendrocyte lineage, along with a closely related CCHC zinc finger, is expressed in developing neurons in the mammalian central nervous system.

Q92766	RREB1_HUMAN	Ras-responsive element-binding protein 1	8816445	RREB-1, a novel zinc finger protein, is involved in the differentiation response to Ras in human medullary thyroid carcinomas.

Q12411	MPC70_YEAST	Sporulation-specific protein 21	12796288	Ady4p and Spo74p are components of the meiotic spindle pole body that promote growth of the prospore membrane in Saccharomyces cerevisiae.

Q39008	M3K1_ARATH	Mitogen-activated protein kinase kinase kinase 1	8570631	A gene encoding a mitogen-activated protein kinase kinase kinase is induced simultaneously with genes for a mitogen-activated protein kinase and an S6 ribosomal protein kinase by touch, cold, and water stress in Arabidopsis thaliana.

Q68EJ0	NB5R4_RAT	Cytochrome b5 reductase 4	11913972	Heterologous expression of an endogenous rat cytochrome b(5)/cytochrome b(5) reductase fusion protein: identification of histidines 62 and 85 as the heme axial ligands.

Q94F62	BAK1_ARATH	BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1	12150928	BRI1/BAK1, a receptor kinase pair mediating brassinosteroid signaling.

Q06218	DBP9_YEAST	ATP-dependent RNA helicase DBP9	11565753	Dbp9p, a putative ATP-dependent RNA helicase involved in 60S- ribosomal-subunit biogenesis, functionally interacts with Dbp6p.

Q39056	CNX3_ARATH	Molybdopterin biosynthesis protein CNX3	7890743	Isolation of two Arabidopsis cDNAs involved in early steps of molybdenum cofactor biosynthesis by functional complementation of Escherichia coli mutants.

Q13488	VPP3_HUMAN	V-type proton ATPase 116 kDa subunit a isoform 3	8579597	Molecular cloning and characterization of a putative novel human osteoclast-specific 116-kDa vacuolar proton pump subunit.

Q56ZI2	PATL2_ARATH	Patellin-2	20543027	The deubiquitinating enzyme AMSH3 is required for intracellular trafficking and vacuole biogenesis in Arabidopsis thaliana.

P26686	SRR55_DROME	Serine-arginine protein 55	1885003	Characterization of a Drosophila protein associated with boundaries of transcriptionally active chromatin.

Q9XI33	WIN1_ARATH	Ethylene-responsive transcription factor WIN1	15319479	The SHINE clade of AP2 domain transcription factors activates wax biosynthesis, alters cuticle properties, and confers drought tolerance when overexpressed in Arabidopsis.

P12844	MYO3_CAEEL	Myosin-3	6352051	Differential localization of two myosins within nematode thick filaments.

Q9QZN9	CNR2_RAT	Cannabinoid receptor 2	10688601	Cloning and pharmacological characterization of the rat CB2 cannabinoid receptor.

Q00961	NMDE3_RAT	Glutamate [NMDA] receptor subunit epsilon-3	7569905	Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95.

Q5QJU3	ACER2_HUMAN	Alkaline ceramidase 2	16940153	Golgi alkaline ceramidase regulates cell proliferation and survival by controlling levels of sphingosine and S1P.

P38930	CSK2C_YEAST	Casein kinase II subunit beta'	8135547	Casein kinase II of Saccharomyces cerevisiae contains two distinct regulatory subunits, beta and beta'.

P17654	AMY1_ORYSJ	Alpha-amylase	2370848	The alpha-amylase genes in Oryza sativa: characterization of cDNA clones and mRNA expression during seed germination.

Q9H161	ALX4_HUMAN	Homeobox protein aristaless-like 4	11106354	The ALX4 homeobox gene is mutated in patients with ossification defects of the skull (foramina parietalia permagna, OMIM 168500).

P81915	OR33B_DROME	Odorant receptor 33b	10069338	A novel family of divergent seven-transmembrane proteins: candidate odorant receptors in Drosophila.

P01761	HV106_HUMAN	Ig heavy chain V-I region SIE	7028111	Amino acid sequence of the variable regions of heavy chains from two idiotypically cross-reactive human IgM anti-gamma-globulins of the Wa group.

P49682	CXCR3_HUMAN	C-X-C chemokine receptor type 3	9064356	Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes.

P17074	RS19_RAT	40S ribosomal protein S19	2116918	The primary structure of rat ribosomal protein S19.

Q9P0X4	CAC1I_HUMAN	Voltage-dependent T-type calcium channel subunit alpha-1I	16740636	Association of Catsper1 or -2 with Ca(v)3.3 leads to suppression of T-type calcium channel activity.

Q80Z64	NANOG_MOUSE	Homeobox protein NANOG	15108323	Identification, cloning and expression analysis of the pluripotency promoting Nanog genes in mouse and human.

Q14994	NR1I3_HUMAN	Nuclear receptor subfamily 1 group I member 3	8114692	A new orphan member of the nuclear hormone receptor superfamily that interacts with a subset of retinoic acid response elements.

P05231	IL6_HUMAN	Interleukin-6	1883960	Marked cell-type-specific differences in glycosylation of human interleukin-6.

Q9Y6K9	NEMO_HUMAN	NF-kappa-B essential modulator	9927690	Identification of a cell protein (FIP-3) as a modulator of NF-kappaB activity and as a target of an adenovirus inhibitor of tumor necrosis factor alpha-induced apoptosis.

Q9SFB7	QRT2_ARATH	Polygalacturonase QRT2	19168715	ARABIDOPSIS DEHISCENCE ZONE POLYGALACTURONASE1 (ADPG1), ADPG2, and QUARTET2 are polygalacturonases required for cell separation during reproductive development in Arabidopsis.

P55931	ETFD_PIG	Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial	17050691	Structure of electron transfer flavoprotein-ubiquinone oxidoreductase and electron transfer to the mitochondrial ubiquinone pool.

Q9UJ41	RABX5_HUMAN	Rab5 GDP/GTP exchange factor	16499958	Crystal structure of the ubiquitin binding domains of rabex-5 reveals two modes of interaction with ubiquitin.

Q9FHW7	SKP1B_ARATH	SKP1-like protein 1B	12169662	The F-box subunit of the SCF E3 complex is encoded by a diverse superfamily of genes in Arabidopsis.

P32121	ARRB2_HUMAN	Beta-arrestin-2	12958365	Beta-arrestin 2 mediates endocytosis of type III TGF-beta receptor and down-regulation of its signaling.

P00890	CISY1_YEAST	Citrate synthase, mitochondrial	11502169	Yeast mitochondrial dehydrogenases are associated in a supramolecular complex.

Q9ZWA6	MGP_ARATH	Zinc finger protein MAGPIE	17785527	Arabidopsis JACKDAW and MAGPIE zinc finger proteins delimit asymmetric cell division and stabilize tissue boundaries by restricting SHORT-ROOT action.

O00268	TAF4_HUMAN	Transcription initiation factor TFIID subunit 4	15960975	Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

P48200	IREB2_HUMAN	Iron-responsive element-binding protein 2	7983023	Molecular characterization of a second iron-responsive element binding protein, iron regulatory protein 2. Structure, function, and post-translational regulation.

Q61730	IL1AP_MOUSE	Interleukin-1 receptor accessory protein	11880380	Identification of essential regions in the cytoplasmic tail of interleukin-1 receptor accessory protein critical for interleukin-1 signaling.

Q6Q5K6	HUG1_YEAST	MEC1-mediated checkpoint protein HUG1	14562095	Global analysis of protein localization in budding yeast.

P53238	PEF1_YEAST	Peflin	14562095	Global analysis of protein localization in budding yeast.

P38758	YHG9_YEAST	UPF0673 membrane protein YHR009C	10684247	The yeast nuclear pore complex: composition, architecture, and transport mechanism.

P52917	VPS4_YEAST	Vacuolar protein sorting-associated protein 4	9155008	Endosomal transport function in yeast requires a novel AAA-type ATPase, Vps4p.

Q925N3	PEX5R_RAT	PEX5-related protein	11278749	Rab8b and its interacting partner TRIP8b are involved in regulated secretion in AtT20 cells.

Q9UT72	RFP2_SCHPO	E3 ubiquitin-protein ligase complex slx8-rfp subunit rfp2	17762865	SUMO-targeted ubiquitin ligases in genome stability.

Q69ZN7	MYOF_MOUSE	Myoferlin	17702744	Myoferlin regulates vascular endothelial growth factor receptor-2 stability and function.

O15374	MOT5_HUMAN	Monocarboxylate transporter 5	9425115	Cloning and sequencing of four new mammalian monocarboxylate transporter (MCT) homologues confirms the existence of a transporter family with an ancient past.

P0C5E2	Y1839_ARATH	Probable serine/threonine-protein kinase At1g18390	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P63044	VAMP2_MOUSE	Vesicle-associated membrane protein 2	17548353	Doc2beta is a novel Munc18c-interacting partner and positive effector of syntaxin 4-mediated exocytosis.

P03877	SCE3_YEAST	Intron-encoded DNA endonuclease aI3	7797552	The mobile group I intron 3 alpha of the yeast mitochondrial COXI gene encodes a 35-kDa processed protein that is an endonuclease but not a maturase.

Q6PD31	TRAK1_MOUSE	Trafficking kinesin-binding protein 1	16380713	Trak1 mutation disrupts GABA(A) receptor homeostasis in hypertonic mice.

Q9BQG0	MBB1A_HUMAN	Myb-binding protein 1A	10644447	Molecular cloning and chromosomal mapping of the human homologue of MYB binding protein (P160) 1A (MYBBP1A) to 17p13.3.

Q924X6	LRP8_MOUSE	Low-density lipoprotein receptor-related protein 8	9685741	Evolution of the apolipoprotein E receptor 2 gene by exon loss.

O01367	HOW_DROME	Protein held out wings	9344542	A novel KH-domain protein mediates cell adhesion processes in Drosophila.

Q9ZWA1	C3H2_ARATH	Zinc finger CCCH domain-containing protein 2	18487351	SOMNUS, a CCCH-type zinc finger protein in Arabidopsis, negatively regulates light-dependent seed germination downstream of PIL5.

Q06651	PIB1_YEAST	E3 ubiquitin-protein ligase PIB1	9702203	Phosphatidylinositol(3)-phosphate signaling mediated by specific binding to RING FYVE domains.

Q9QUP4	CHST5_MOUSE	Carbohydrate sulfotransferase 5	11278593	Human corneal GlcNAc 6-O-sulfotransferase and mouse intestinal GlcNAc 6-O-sulfotransferase both produce keratan sulfate.

Q07879	ATG10_YEAST	Ubiquitin-like-conjugating enzyme ATG10	9759731	A protein conjugation system essential for autophagy.

O95995	GAS8_HUMAN	Growth arrest-specific protein 8	9790751	Characterization and screening for mutations of the growth arrest- specific 11 (GAS11) and C16orf3 genes at 16q24.3 in breast cancer.

P32614	FRDS_YEAST	Fumarate reductase	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P32561	RPD3_YEAST	Histone deacetylase RPD3	9572144	Transcriptional repression by UME6 involves deacetylation of lysine 5 of histone H4 by RPD3.

Q15208	STK38_HUMAN	Serine/threonine-protein kinase 38	17906693	Negative regulation of MEKK1/2 signaling by serine-threonine kinase 38 (STK38).

P0A7C2	LEXA_ECOLI	LexA repressor	7027255	Purified lexA protein is a repressor of the recA and lexA genes.

P41808	SMK1_YEAST	Sporulation-specific mitogen-activated protein kinase SMK1	16116083	The Smk1p MAP kinase negatively regulates Gsc2p, a 1,3-beta-glucan synthase, during spore wall morphogenesis in Saccharomyces cerevisiae.

Q93038	TNR25_HUMAN	Tumor necrosis factor receptor superfamily member 25	8994832	Apo-3, a new member of the tumor necrosis factor receptor family, contains a death domain and activates apoptosis and NF-kappa-B.

P81270	ERG_MOUSE	Transcriptional regulator ERG	11791185	Molecular cloning of ESET, a novel histone H3-specific methyltransferase that interacts with ERG transcription factor.

P53290	GTR2_YEAST	GTP-binding protein GTR2	16732272	A conserved GTPase-containing complex is required for intracellular sorting of the general amino-acid permease in yeast.

Q12923	PTN13_HUMAN	Tyrosine-protein phosphatase non-receptor type 13	7929060	Cloning and characterization of PTPL1, a protein tyrosine phosphatase with similarities to cytoskeletal-associated proteins.

O60240	PLIN1_HUMAN	Perilipin-1	9521880	Isolation and chromosomal mapping of the human homolog of perilipin (PLIN), a rat adipose tissue-specific gene, by differential display method.

Q62784	INP4A_RAT	Type I inositol-3,4-bisphosphate 4-phosphatase	7608176	The isolation and characterization of cDNA encoding human and rat brain inositol polyphosphate 4-phosphatase.

O94525	YBU1_SCHPO	Uncharacterized ribonuclease C609.01	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NY87	SPNXC_HUMAN	Sperm protein associated with the nucleus on the X chromosome C	10626816	CTp11, a novel member of the family of cancer-testis antigens.

Q9CX60	LBH_MOUSE	Protein LBH	11336496	Identification and characterization of Lbh, a novel conserved nuclear protein expressed during early limb and heart development.

Q7SZE3	L2GL2_DANRE	Lethal(2) giant larvae protein homolog 2	15983403	Zebrafish penner/lethal giant larvae 2 functions in hemidesmosome formation, maintenance of cellular morphology and growth regulation in the developing basal epidermis.

Q8R0L9	TADA3_MOUSE	Transcriptional adapter 3	12034840	ADA3-containing complexes associate with estrogen receptor alpha.

Q54J97	CH60_DICDI	60 kDa heat shock protein, mitochondrial	12952082	Chaperonin 60 and mitochondrial disease in Dictyostelium.

P29373	RABP2_HUMAN	Cellular retinoic acid-binding protein 2	1334086	Structure of the human cellular retinoic acid-binding protein II gene. Early transcriptional regulation by retinoic acid.

Q9Y806	ERV2_SCHPO	FAD-linked sulfhydryl oxidase erv2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9ERE7	MESD_MOUSE	LDLR chaperone MESD	11247670	Identification of mesoderm development (mesd) candidate genes by comparative mapping and genome sequence analysis.

Q03690	TIF31_YEAST	Protein TIF31	10358023	A 110-kilodalton subunit of translation initiation factor eIF3 and an associated 135-kilodalton protein are encoded by the Saccharomyces cerevisiae TIF32 and TIF31 genes.

Q62936	DLG3_RAT	Disks large homolog 3	16495444	A novel family of adhesion-like molecules that interacts with the NMDA receptor.

Q9UJT9	FBXL7_HUMAN	F-box/LRR-repeat protein 7	10531035	Identification of a family of human F-box proteins.

O94473	YC64_SCHPO	Uncharacterized membrane protein C1919.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q01532	BLH1_YEAST	Cysteine proteinase 1, mitochondrial	16769724	Protective mechanisms against homocysteine toxicity: the role of bleomycin hydrolase.

Q9NR80	ARHG4_HUMAN	Rho guanine nucleotide exchange factor 4	10947987	Asef, a link between the tumor suppressor APC and G-protein signaling.

Q02206	RSC4_YEAST	Chromatin structure-remodeling complex subunit RSC4	8980231	RSC, an essential, abundant chromatin-remodeling complex.

P58985	GR59D_DROME	Putative gustatory receptor 59d	10710312	Candidate taste receptors in Drosophila.

P77202	DSBG_ECOLI	Thiol:disulfide interchange protein DsbG	10075670	In vivo and in vitro function of the Escherichia coli periplasmic cysteine oxidoreductase DsbG.

P28795	PEX3_YEAST	Peroxisomal biogenesis factor 3	1894692	PAS3, a Saccharomyces cerevisiae gene encoding a peroxisomal integral membrane protein essential for peroxisome biogenesis.

O14640	DVL1_HUMAN	Segment polarity protein dishevelled homolog DVL-1	14750955	Identification and characterization of a novel Dvl-binding protein that suppresses Wnt signalling pathway.

P26368	U2AF2_HUMAN	Splicing factor U2AF 65 kDa subunit	11551507	A novel peptide recognition mode revealed by the X-ray structure of a core U2AF35/U2AF65 heterodimer.

P42575	CASP2_HUMAN	Caspase-2	16652156	Functional connection between p53 and caspase-2 is essential for apoptosis induced by DNA damage.

P19883	FST_HUMAN	Follistatin	16198295	The structure of the follistatin:activin complex reveals antagonism of both type I and type II receptor binding.

O95786	DDX58_HUMAN	Probable ATP-dependent RNA helicase DDX58	19631370	RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway.

Q13362	2A5G_HUMAN	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform	17174897	Structure of the protein phosphatase 2A holoenzyme.

Q54NF8	SCAR_DICDI	Protein SCAR	9732292	SCAR, a WASP-related protein, isolated as a suppressor of receptor defects in late Dictyostelium development.

P24100	CDKA1_ARATH	Cyclin-dependent kinase A-1	15197472	Molecular characterization of Arabidopsis PHO80-like proteins, a novel class of CDKA;1-interacting cyclins.

Q99LD4	CSN1_MOUSE	COP9 signalosome complex subunit 1	9707402	The COP9 complex is conserved between plants and mammals and is related to the 26S proteasome regulatory complex.

Q21815	MIG23_CAEEL	Nucleoside-diphosphatase mig-23	14688791	An NDPase links ADAM protease glycosylation with organ morphogenesis in C. elegans.

Q9NRL3	STRN4_HUMAN	Striatin-4	10748158	Zinedin, SG2NA, and striatin are calmodulin-binding, WD repeat proteins principally expressed in the brain.

Q12282	YO214_YEAST	Cell wall protein YOR214C	10383953	Amino acid residues in the omega-minus region participate in cellular localization of yeast glycosylphosphatidylinositol-attached proteins.

P41565	IDH3G_RAT	Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial	8240232	Molecular cloning and deduced amino acid sequences of the gamma- subunits of rat and monkey NAD(+)-isocitrate dehydrogenases.

Q3KQ35	S17AA_XENLA	Transcription factor Sox-17-alpha-A	11518513	VegT activation of Sox17 at the midblastula transition alters the response to nodal signals in the vegetal endoderm domain.

Q8MQU6	CISYP_DICDI	Citrate synthase, peroxisomal	15225305	Disruption of the peroxisomal citrate synthase CshA affects cell growth and multicellular development in Dictyostelium discoideum.

O43660	PLRG1_HUMAN	Pleiotropic regulator 1	9765207	Pleiotropic control of glucose and hormone responses by PRL1, a nuclear WD protein, in Arabidopsis.

O74736	ING2_SCHPO	Chromatin modification-related protein png2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q13642	FHL1_HUMAN	Four and a half LIM domains protein 1	7626119	The developmental regulation of a novel muscle LIM-protein.

Q9VUQ5	AGO2_DROME	Protein argonaute-2	12368261	A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins.

Q01815	CAC1C_MOUSE	Voltage-dependent L-type calcium channel subunit alpha-1C	7814415	Cloning and expression of a novel truncated calcium channel from non- excitable cells.

P07713	DECA_DROME	Protein decapentaplegic	11432817	Nuclear interpretation of Dpp signaling in Drosophila.

P07910	HNRPC_HUMAN	Heterogeneous nuclear ribonucleoproteins C1/C2	3110598	Primary structure of human nuclear ribonucleoprotein particle C proteins: conservation of sequence and domain structures in heterogeneous nuclear RNA, mRNA, and pre-rRNA-binding proteins.

P78325	ADAM8_HUMAN	Disintegrin and metalloproteinase domain-containing protein 8	15574124	FLRG, a new ADAM12-associated protein, modulates osteoclast differentiation.

O95221	OR5F1_HUMAN	Olfactory receptor 5F1	9787077	Organization and evolution of olfactory receptor genes on human chromosome 11.

B2RUP2	UN13D_MOUSE	Protein unc-13 homolog D	18354201	Doc2 alpha and Munc13-4 regulate Ca(2+) -dependent secretory lysosome exocytosis in mast cells.

Q9YGY0	AXN1_XENLA	Axin-1	14600025	Crystal structure of a beta-catenin/axin complex suggests a mechanism for the beta-catenin destruction complex.

Q8IZU3	SYCP3_HUMAN	Synaptonemal complex protein 3	14643120	Azoospermia in patients heterozygous for a mutation in SYCP3.

Q54FI3	PKS37_DICDI	Probable polyketide synthase 37	16906151	Biosynthesis of Dictyostelium discoideum differentiation-inducing factor by a hybrid type I fatty acid-type III polyketide synthase.

P70056	FOXH1_XENLA	Forkhead box protein H1	10349617	A mouse homologue of FAST-1 transduces TGF beta superfamily signals and is expressed during early embryogenesis.

P43405	KSYK_HUMAN	Tyrosine-protein kinase SYK	8163536	Molecular cloning of human Syk. A B cell protein-tyrosine kinase associated with the surface immunoglobulin M-B cell receptor complex.

P84909	PROK1_RANSA	Prokineticin 1-like protein	16269346	Isolation and structural characterization of novel Rugosin A-like insulinotropic peptide from the skin secretions of Rana saharica frog.

Q8R5G7	ARAP3_MOUSE	Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3	15546919	ARAP3 is transiently tyrosine phosphorylated in cells attaching to fibronectin and inhibits cell spreading in a RhoGAP-dependent manner.

P01767	HV306_HUMAN	Ig heavy chain V-III region BUT	416441	Complete amino acid sequence of the alpha 2 heavy chain of a human IgA2 immunoglobulin of the A2m (2) allotype.

Q12745	SEC39_YEAST	Protein transport protein SEC39	15958492	Dsl1p, Tip20p, and the novel Dsl3(Sec39) protein are required for the stability of the Q/t-SNARE complex at the endoplasmic reticulum in yeast.

P49795	RGS19_HUMAN	Regulator of G-protein signaling 19	8524874	GAIP, a protein that specifically interacts with the trimeric G protein G alpha i3, is a member of a protein family with a highly conserved core domain.

Q8NI35	INADL_HUMAN	InaD-like protein	9280290	Molecular characterization of a novel PDZ domain protein with homology to INAD from Drosophila melanogaster.

Q15819	UB2V2_HUMAN	Ubiquitin-conjugating enzyme E2 variant 2	11473255	Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13.

Q9BQ15	SOSB1_HUMAN	SOSS complex subunit B1	19683501	SOSS complexes participate in the maintenance of genomic stability.

Q9ZQ95	FOGT1_ARATH	Flavonol-3-O-glycoside-7-O-glucosyltransferase 1	12900416	UGT73C6 and UGT78D1, glycosyltransferases involved in flavonol glycoside biosynthesis in Arabidopsis thaliana.

Q9NHX0	RBX1B_DROME	RING-box protein 1B	12062088	Drosophila Roc1a encodes a RING-H2 protein with a unique function in processing the Hh signal transducer Ci by the SCF E3 ubiquitin ligase.

Q3TUH1	MMP37_MOUSE	MMP37-like protein, mitochondrial	14651853	Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.

Q03433	VPS71_YEAST	Vacuolar protein sorting-associated protein 71	14645854	ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex.

Q29983	MICA_HUMAN	MHC class I polypeptide-related sequence A	9497295	Recognition of stress-induced MHC molecules by intestinal epithelial gammadelta T cells.

P38731	ARN1_YEAST	Siderophore iron transporter ARN1	10748025	Siderophore-iron uptake in Saccharomyces cerevisiae. Identification of ferrichrome and fusarinine transporters.

P42570	PLU_DROME	DNA replication inhibitor plutonium	8313891	The inhibitor of DNA replication encoded by the Drosophila gene plutonium is a small, ankyrin repeat protein.

Q9S9U6	1A111_ARATH	1-aminocyclopropane-1-carboxylate synthase 11	12968022	Biochemical diversity among the 1-amino-cyclopropane-1-carboxylate synthase isozymes encoded by the Arabidopsis gene family.

O54853	KCNH6_RAT	Potassium voltage-gated channel subfamily H member 6	11212207	Erg1, erg2 and erg3 K channel subunits are able to form heteromultimers.

Q13057	COASY_HUMAN	Bifunctional coenzyme A synthase	11994049	Identification and characterization of the gene encoding the human phosphopantetheine adenylyltransferase and dephospho-CoA kinase bifunctional enzyme (CoA synthase).

P84680	SC35_TITCA	Toxin Tc35	15025998	Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

P10862	RAD18_YEAST	Postreplication repair E3 ubiquitin-protein ligase RAD18	10880451	Two RING finger proteins mediate cooperation between ubiquitin- conjugating enzymes in DNA repair.

P32783	MCES_YEAST	mRNA cap guanine-N7 methyltransferase	11018011	Dynamic association of capping enzymes with transcribing RNA polymerase II.

Q9JJF3	NO66_MOUSE	Lysine-specific demethylase NO66	14742713	NO66, a highly conserved dual location protein in the nucleolus and in a special type of synchronously replicating chromatin.

P36581	CALX_SCHPO	Calnexin homolog	7621821	The calnexin homologue cnx1+ in Schizosaccharomyces pombe, is an essential gene which can be complemented by its soluble ER domain.

P83944	ALR_PENMO	Alanine racemase	12431412	Purification, properties, and partial amino acid sequences of alanine racemase from the muscle of the black tiger prawn Penaeus monodon.

Q91V08	CLC2D_MOUSE	C-type lectin domain family 2 member D	14990792	Missing self-recognition of Ocil/Clr-b by inhibitory NKR-P1 natural killer cell receptors.

P70257	NFIX_MOUSE	Nuclear factor 1 X-type	9056636	Expression patterns of the four nuclear factor I genes during mouse embryogenesis indicate a potential role in development.

P67809	YBOX1_HUMAN	Nuclease-sensitive element-binding protein 1	18335541	MBNL1 associates with YB-1 in cytoplasmic stress granules.

P51521	OVO_DROME	Protein ovo	10637336	Characterization of Drosophila OVO protein DNA binding specificity using random DNA oligomer selection suggests zinc finger degeneration.

Q9Z2F5	CTBP1_RAT	C-terminal-binding protein 1	12805226	CtBP/BARS: a dual-function protein involved in transcription co- repression and Golgi membrane fission.

Q96J94	PIWL1_HUMAN	Piwi-like protein 1	14749716	Characterization of the interactions between mammalian PAZ PIWI domain proteins and Dicer.

Q9Y7L8	RSSA1_SCHPO	40S ribosomal protein S0-A	14623272	Ribosomal proteins S0 and S21 are involved in the stability of 18S rRNA in fission yeast, Schizosaccharomyces pombe.

Q55GS2	SCY1_DICDI	Probable inactive serine/threonine-protein kinase scy1	15548420	Molecular and functional analysis of the dictyostelium centrosome.

O14133	ATE1_SCHPO	Arginyl-tRNA--protein transferase 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Z330	DNMT1_RAT	DNA (cytosine-5)-methyltransferase 1	9878564	Expression of rat DNA (cytosine-5) methyltransferase (DNA MTase) in rodent trophoblast giant cells: molecular cloning and characterization of rat DNA MTase.

Q9U1M8	MYOI_DICDI	Myosin-I heavy chain	11267868	A role for myosin VII in dynamic cell adhesion.

O94522	RSC7_SCHPO	Chromatin structure-remodeling complex subunit rsc7	18622392	Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast.

Q98SK0	MDFIC_XENLA	MyoD family inhibitor domain-containing protein	11238923	Inhibition of Tcf3 binding by I-mfa domain proteins.

Q15329	E2F5_HUMAN	Transcription factor E2F5	7892279	E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle.

P32969	RL9_HUMAN	60S ribosomal protein L9	8597601	Structural organization and chromosomal localization of the human ribosomal protein L9 gene.

Q8JGN5	BI51A_XENLA	Baculoviral IAP repeat-containing protein 5.1-A	16322459	Chromosome alignment and segregation regulated by ubiquitination of survivin.

O96020	CCNE2_HUMAN	G1/S-specific cyclin-E2	9858585	Cyclin E2, a novel G1 cyclin that binds Cdk2 and is aberrantly expressed in human cancers.

O13790	CUL1_SCHPO	Cullin-1	15147268	Molecular interactions of fission yeast Skp1 and its role in the DNA damage checkpoint.

Q9P7B0	STB3_SCHPO	Protein STB3 homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8R0L1	STAP2_MOUSE	Signal-transducing adaptor protein 2	12540842	STAP-2/BKS, an adaptor/docking protein, modulates STAT3 activation in acute-phase response through its YXXQ motif.

P55774	CCL18_HUMAN	C-C motif chemokine 18	9233607	A novel human CC chemokine PARC that is most homologous to macrophage-inflammatory protein-1 alpha/LD78 alpha and chemotactic for T lymphocytes, but not for monocytes.

P70567	TMOD1_RAT	Tropomodulin-1	8886980	N-tropomodulin: a novel isoform of tropomodulin identified as the major binding protein to brain tropomyosin.

P38418	LOX2_ARATH	Lipoxygenase 2, chloroplastic	15322131	New functions of the thylakoid membrane proteome of Arabidopsis thaliana revealed by a simple, fast, and versatile fractionation strategy.

O74535	CPSFX_SCHPO	Cleavage and polyadenylation factor complex subunit C74.02c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P09622	DLDH_HUMAN	Dihydrolipoyl dehydrogenase, mitochondrial	3278312	Cloning and cDNA sequence of the dihydrolipoamide dehydrogenase component human alpha-ketoacid dehydrogenase complexes.

Q9NVH6	TMLH_HUMAN	Trimethyllysine dioxygenase, mitochondrial	11431483	Molecular and biochemical characterization of rat epsilon-N- trimethyllysine hydroxylase, the first enzyme of carnitine biosynthesis.

Q99PP7	TRI33_MOUSE	E3 ubiquitin-protein ligase TRIM33	15314655	The zebrafish moonshine gene encodes transcriptional intermediary factor 1 gamma, an essential regulator of hematopoiesis.

Q9FXE5	FUCO3_ARATH	Alpha-L-fucosidase 3	11788770	AtFXG1, an Arabidopsis gene encoding alpha-L-fucosidase active against fucosylated xyloglucan oligosaccharides.

Q92624	APBP2_HUMAN	Amyloid protein-binding protein 2	9843960	PAT1, a microtubule-interacting protein, recognizes the basolateral sorting signal of amyloid precursor protein.

P43616	DUG1_YEAST	Cys-Gly metallodipeptidase DUG1	17179087	The alternative pathway of glutathione degradation is mediated by a novel protein complex involving three new genes in Saccharomyces cerevisiae.

P20433	RPB4_YEAST	DNA-directed RNA polymerase II subunit RPB4	16357218	The RNA polymerase II subunit Rpb4p mediates decay of a specific class of mRNAs.

O35790	PIGL_RAT	N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase	9188481	Expression cloning of PIG-L, a candidate N-acetylglucosaminyl- phosphatidylinositol deacetylase.

Q9P0S3	ORML1_HUMAN	ORM1-like protein 1	12093374	ORMDL proteins are a conserved new family of endoplasmic reticulum membrane proteins.

Q8UVJ6	VANG2_DANRE	Vang-like protein 2	11820812	The Zebrafish trilobite gene is essential for tangential migration of branchiomotor neurons.

Q9V9A7	MCCB_DROME	Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial	9584098	Genes expressed in the ring gland, the major endocrine organ of Drosophila melanogaster.

Q8MLV1	LBR_DROME	Lamin-B receptor	15054108	The lamin B receptor of Drosophila melanogaster.

Q9ESN9	JIP3_MOUSE	C-Jun-amino-terminal kinase-interacting protein 3	10629060	Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3.

Q9NXF1	TEX10_HUMAN	Testis-expressed sequence 10 protein	15960975	Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

Q12959	DLG1_HUMAN	Disks large homolog 1	7937897	Cloning and characterization of hdlg: the human homologue of the Drosophila discs large tumor suppressor binds to protein 4.1.

O15528	CP27B_HUMAN	25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	9415400	Cloning of human 25-hydroxyvitamin D-1 alpha-hydroxylase and mutations causing vitamin D-dependent rickets type 1.

Q92747	ARC1A_HUMAN	Actin-related protein 2/3 complex subunit 1A	8978670	Fission yeast Sop2p: a novel and evolutionarily conserved protein that interacts with Arp3p and modulates profilin function.

P52788	SPSY_HUMAN	Spermine synthase	9299240	Sequence analysis of 139 kb in Xp22.1 containing spermine synthase and the 5' region of PEX.

Q07436	EXPA_DROME	Protein expanded	20159598	Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded.

P85215	DEF2_GALME	Defensin-like peptide	17194500	Purification and characterization of eight peptides from Galleria mellonella immune hemolymph.

Q04439	MYO5_YEAST	Myosin-5	11901111	The novel adaptor protein, Mti1p, and Vrp1p, a homolog of Wiskott- Aldrich syndrome protein-interacting protein (WIP), may antagonistically regulate type I myosins in Saccharomyces cerevisiae.

P10863	TIR1_YEAST	Cold shock-induced protein TIR1	15781460	Comprehensive proteomic analysis of Saccharomyces cerevisiae cell walls: identification of proteins covalently attached via glycosylphosphatidylinositol remnants or mild alkali-sensitive linkages.

Q62812	MYH9_RAT	Myosin-9	15505042	Pdlim2, a novel PDZ-LIM domain protein, interacts with alpha-actinins and filamin A.

Q9Y3C5	RNF11_HUMAN	RING finger protein 11	10673045	Cloning and expression profile of mouse and human genes, Rnf11/RNF11, encoding a novel RING-H2 finger protein.

P76045	OMPG_ECOLI	Outer membrane protein G	9721282	Biochemistry and regulation of a novel Escherichia coli K-12 porin protein, OmpG, which produces unusually large channels.

Q9SKT3	SCAM1_ARATH	Secretory carrier-associated membrane protein 1	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q9UUE3	YNZ6_SCHPO	Putative lysine N-acyltransferase C17G9.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q64305	PTF1A_RAT	Pancreas transcription factor 1 subunit alpha	10768861	Role of the basic helix-loop-helix transcription factor p48 in the differentiation phenotype of exocrine pancreas cancer cells.

Q55CK2	MGP2_DICDI	Mental retardation GTPase activating protein homolog 2	18334553	Dictyostelium MEGAPs: F-BAR domain proteins that regulate motility and membrane tubulation in contractile vacuoles.

O75362	ZN217_HUMAN	Zinc finger protein 217	16940172	Specific recognition of ZNF217 and other zinc finger proteins at a surface groove of C-terminal binding proteins.

P49597	P2C56_ARATH	Protein phosphatase 2C 56	15923322	Heat stress phenotypes of Arabidopsis mutants implicate multiple signaling pathways in the acquisition of thermotolerance.

O74773	MSH2_SCHPO	DNA mismatch repair protein msh2	9858548	The msh2 gene of Schizosaccharomyces pombe is involved in mismatch repair, mating-type switching, and meiotic chromosome organization.

P20786	PGFRA_RAT	Alpha-type platelet-derived growth factor receptor	2157969	Isolation and characterization of the alpha platelet-derived growth factor receptor from rat olfactory epithelium.

Q9Y3S2	ZN330_HUMAN	Zinc finger protein 330	10593942	Molecular cloning of a zinc finger autoantigen transiently associated with interphase nucleolus and mitotic centromeres and midbodies. Orthologous proteins with nine CXXC motifs highly conserved from nematodes to humans.

P51653	GPC2_RAT	Glypican-2	8294498	Cerebroglycan: an integral membrane heparan sulfate proteoglycan that is unique to the developing nervous system and expressed specifically during neuronal differentiation.

Q14289	FAK2_HUMAN	Protein-tyrosine kinase 2-beta	7499242	Identification and characterization of a novel related adhesion focal tyrosine kinase (RAFTK) from megakaryocytes and brain.

Q16665	HIF1A_HUMAN	Hypoxia-inducible factor 1-alpha	17956732	RSUME, a small RWD-containing protein, enhances SUMO conjugation and stabilizes HIF-1alpha during hypoxia.

Q652V8	HSP16_ORYSJ	16.0 kDa heat shock protein, peroxisomal	19703271	Rice sHsp genes: genomic organization and expression profiling under stress and development.

P84198	VIME_CERAE	Vimentin	10887173	Calyculin A-induced vimentin phosphorylation sequesters 14-3-3 and displaces other 14-3-3 partners in vivo.

Q9BXT6	M10L1_HUMAN	Putative helicase Mov10l1	11279525	An abundance of X-linked genes expressed in spermatogonia.

Q9JMI1	AACS_RAT	Acetoacetyl-CoA synthetase	16055091	Acetoacetyl-CoA synthetase gene is abundant in rat adipose, and related with fatty acid synthesis in mature adipocytes.

Q9UUJ4	REC24_SCHPO	Meiotic recombination protein rec24	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P40199	CEAM6_HUMAN	Carcinoembryonic antigen-related cell adhesion molecule 6	3220478	Carcinoembryonic antigen family: characterization of cDNAs coding for NCA and CEA and suggestion of nonrandom sequence variation in their conserved loop-domains.

P58681	TLR7_MOUSE	Toll-like receptor 7	14976261	Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA.

O08725	GHSR_RAT	Growth hormone secretagogue receptor type 1	10604470	Ghrelin is a growth-hormone-releasing acylated peptide from stomach.

Q04006	YD185_YEAST	PRELI/MSF1 domain-containing protein YDR185C	14562095	Global analysis of protein localization in budding yeast.

P22141	PSB2_YEAST	Proteasome component C11	9087403	Structure of 20S proteasome from yeast at 2.4-A resolution.

Q12056	ISU2_YEAST	Iron sulfur cluster assembly protein 2, mitochondrial	10468587	Evidence for a conserved system for iron metabolism in the mitochondria of Saccharomyces cerevisiae.

Q05683	DCE2_RAT	Glutamate decarboxylase 2	8132714	Amino acid residues 24-31 but not palmitoylation of cysteines 30 and 45 are required for membrane anchoring of glutamic acid decarboxylase, GAD65.

Q38872	CDPK6_ARATH	Calcium-dependent protein kinase 6	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

Q8LG64	CKB22_ARATH	Cyclin-dependent kinase B2-2	11432958	Identification of novel cyclin-dependent kinases interacting with the CKS1 protein of Arabidopsis.

Q0VAV2	EXPH5_MOUSE	Exophilin-5	11773082	The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain.

Q8K4J0	DCR1C_MOUSE	Protein artemis	12504013	Leaky Scid phenotype associated with defective V(D)J coding end processing in Artemis-deficient mice.

Q8GZM7	PIF1_ARATH	Transcription factor PIF1	15448264	Phytochrome-interacting factor 1 is a critical bHLH regulator of chlorophyll biosynthesis.

O13610	FCF1_SCHPO	rRNA-processing protein fcf1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P05556	ITB1_HUMAN	Integrin beta-1	16076904	The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins.

P40360	NAGS_YEAST	Amino-acid acetyltransferase, mitochondrial	11553611	A new yeast metabolon involving at least the two first enzymes of arginine biosynthesis: acetylglutamate synthase activity requires complex formation with acetylglutamate kinase.

Q9ERS4	PKHA3_MOUSE	Pleckstrin homology domain-containing family A member 3	11001876	Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities.

Q68CZ1	FTM_HUMAN	Protein fantom	17558409	The ciliary gene RPGRIP1L is mutated in cerebello-oculo-renal syndrome (Joubert syndrome type B) and Meckel syndrome.

Q23288	VIPAR_CAEEL	VPS33B-interacting protein	19109425	SPE-39 family proteins interact with the HOPS complex and function in lysosomal delivery.

P53093	YIP4_YEAST	Protein YIP4	11943201	Identification of the novel proteins Yip4p and Yip5p as Rab GTPase interacting factors.

Q9P0G3	KLK14_HUMAN	Kallikrein-14	17158887	A potential role for multiple tissue kallikrein serine proteases in epidermal desquamation.

P12686	RT13_YEAST	37S ribosomal protein MRP13, mitochondrial	12392552	Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components.

Q27874	PAT3_CAEEL	Integrin beta pat-3	7744961	Characterization of beta pat-3 heterodimers, a family of essential integrin receptors in C. elegans.

P08729	K2C7_HUMAN	Keratin, type II cytoskeletal 7	10492017	Sarcolectin (SCL): structure and expression of the recombinant molecule.

Q58634	PSB_METJA	Proteasome subunit beta	10692374	Biochemical and physical properties of the Methanococcus jannaschii 20S proteasome and PAN, a homolog of the ATPase (Rpt) subunits of the eucaryal 26S proteasome.

P49893	WN11B_XENLA	Protein Wnt-11b	17202189	Wnt11/beta-catenin signaling in both oocytes and early embryos acts through LRP6-mediated regulation of axin.

P28023	DCTN1_RAT	Dynactin subunit 1	1828535	Homology of a 150K cytoplasmic dynein-associated polypeptide with the Drosophila gene Glued.

P36051	MCD4_YEAST	GPI ethanolamine phosphate transferase 1	16704983	Ethanolaminephosphate side chain added to glycosylphosphatidylinositol (GPI) anchor by mcd4p is required for ceramide remodeling and forward transport of GPI proteins from endoplasmic reticulum to Golgi.

Q68KI4	NHX1_ARATH	Sodium/hydrogen exchanger 1	16249341	Vacuolar Na(+)/H(+) antiporter cation selectivity is regulated by calmodulin from within the vacuole in a Ca2(+)- and pH-dependent manner.

P09914	IFIT1_HUMAN	Interferon-induced protein with tetratricopeptide repeats 1	3753936	Molecular cloning, full-length sequence and preliminary characterization of a 56-kDa protein induced by human interferons.

P34152	FAK1_MOUSE	Focal adhesion kinase 1	9461600	A role for CAP, a novel, multifunctional Src homology 3 domain- containing protein in formation of actin stress fibers and focal adhesions.

Q03178	PIR1_YEAST	Cell wall mannoprotein PIR1	9301021	Specific labelling of cell wall proteins by biotinylation. Identification of four covalently linked O-mannosylated proteins of Saccharomyces cerevisiae.

P33400	PACC_YEAST	pH-response transcription factor pacC/RIM101	11698381	Yeast PalA/AIP1/Alix homolog Rim20p associates with a PEST-like region and is required for its proteolytic cleavage.

Q63618	ESPN_RAT	Espin	8799813	Identification and characterization of espin, an actin-binding protein localized to the F-actin-rich junctional plaques of Sertoli cell ectoplasmic specializations.

Q07457	BRE1_YEAST	E3 ubiquitin-protein ligase BRE1	15280549	Rad6-Bre1-mediated histone H2B ubiquitylation modulates the formation of double-strand breaks during meiosis.

Q15796	SMAD2_HUMAN	Mothers against decapentaplegic homolog 2	17292623	Fussel-15, a novel Ski/Sno homolog protein, antagonizes BMP signaling.

P63167	DYL1_HUMAN	Dynein light chain 1, cytoplasmic	15891768	Functional regulation of oestrogen receptor pathway by the dynein light chain 1.

P35133	UBC10_ARATH	Ubiquitin-conjugating enzyme E2 10	16339806	Genome analysis and functional characterization of the E2 and RING- type E3 ligase ubiquitination enzymes of Arabidopsis.

Q9ZZX1	SCE4_YEAST	Intron-encoded DNA endonuclease aI5 alpha	9872396	The complete sequence of the mitochondrial genome of Saccharomyces cerevisiae.

P48794	HYALP_MOUSE	Hyaluronidase PH-20	12065596	Mouse sperm lacking cell surface hyaluronidase PH-20 can pass through the layer of cumulus cells and fertilize the egg.

O75147	OBSL1_HUMAN	Obscurin-like protein 1	17289344	Obscurin-like 1, OBSL1, is a novel cytoskeletal protein related to obscurin.

P78363	ABCA4_HUMAN	Retinal-specific ATP-binding cassette transporter	9054934	A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy.

Q76MX4	MAFG_RAT	Transcription factor MafG	11583919	MafG-2 is a novel Maf protein that is expressed by stimulation of extracellular H(+).

O82662	SUCB_ARATH	Succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial	11743114	Proteomic approach to identify novel mitochondrial proteins in Arabidopsis.

Q99638	RAD9A_HUMAN	Cell cycle checkpoint control protein RAD9A	12628935	Protein kinase Cdelta is responsible for constitutive and DNA damage- induced phosphorylation of Rad9.

P87308	LSB5_SCHPO	Protein lsb5	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9WU49	CHSP1_RAT	Calcium-regulated heat stable protein 1	9712905	Purification and characterization of a novel physiological substrate for calcineurin in mammalian cells.

P13231	HATA_DICDI	Hisactophilin-1	2914932	Hisactophilin, a histidine-rich actin-binding protein from Dictyostelium discoideum.

P39742	SEC72_YEAST	Translocation protein SEC72	7758110	Posttranslational protein transport in yeast reconstituted with a purified complex of Sec proteins and Kar2p.

P47939	RES18_MOUSE	Regulated endocrine-specific protein 18	7988462	Regulated endocrine-specific protein-18: a short-lived novel glucocorticoid-regulated endocrine protein.

Q9VLJ6	ACER_DROME	Angiotensin-converting enzyme-related protein	12075344	Angiotensin-converting enzyme 2 is an essential regulator of heart function.

O13286	SRW1_SCHPO	WD repeat-containing protein srw1	9736616	Apc10 and Ste9/Srw1, two regulators of the APC-cyclosome, as well as the CDK inhibitor Rum1 are required for G1 cell-cycle arrest in fission yeast.

P61407	TDRD6_MOUSE	Tudor domain-containing protein 6	19345099	Tdrd6 is required for spermiogenesis, chromatoid body architecture, and regulation of miRNA expression.

Q8GYE0	PHF1_ARATH	SEC12-like protein 1	16284308	PHOSPHATE TRANSPORTER TRAFFIC FACILITATOR1 is a plant-specific SEC12- related protein that enables the endoplasmic reticulum exit of a high- affinity phosphate transporter in Arabidopsis.

P49744	TSP4_RAT	Thrombospondin-4	7490284	Thrombospondin-4, an extracellular matrix protein expressed in the developing and adult nervous system promotes neurite outgrowth.

O15440	MRP5_HUMAN	Multidrug resistance-associated protein 5	9827529	Characterization of MOAT-C and MOAT-D, new members of the MRP/cMOAT subfamily of transporter proteins.

P51965	UB2E1_HUMAN	Ubiquitin-conjugating enzyme E2 E1	18845142	The autoantigen Ro52 is an E3 ligase resident in the cytoplasm but enters the nucleus upon cellular exposure to nitric oxide.

O88275	PPARG_RAT	Peroxisome proliferator-activated receptor gamma	10438514	Rat peroxisome proliferator-activated receptors and brown adipose tissue function during cold acclimatization.

P53193	JAC1_YEAST	J-type co-chaperone JAC1, mitochondrial	11278728	J-domain protein, Jac1p, of yeast mitochondria required for iron homeostasis and activity of Fe-S cluster proteins.

Q9W2Q7	IPPK_DROME	Inositol-pentakisphosphate 2-kinase	15322119	A molecular basis for inositol polyphosphate synthesis in Drosophila melanogaster.

P36969	GPX4_HUMAN	Phospholipid hydroperoxide glutathione peroxidase, mitochondrial	8039723	Cloning and sequencing of the cDNA encoding a human testis phospholipid hydroperoxide glutathione peroxidase.

Q9R069	BCAM_MOUSE	Basal cell adhesion molecule	10630290	Characterization of a mouse laminin receptor gene homologous to the human blood group Lutheran gene.

Q02158	PLC_DICDI	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase	1326523	Molecular cloning and expression of a phosphoinositide-specific phospholipase C of Dictyostelium discoideum.

P46783	RS10_HUMAN	40S ribosomal protein S10	7772601	Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs.

P37361	MT3_RAT	Metallothionein-3	7677777	Modulation of metallothionein-III mRNA content and growth rate of rat C6-glial cells by transfection with human 5-HT1D receptor genes.

P40087	DDI1_YEAST	DNA damage-inducible protein 1	10330187	Yeast VSM1 encodes a v-SNARE binding protein that may act as a negative regulator of constitutive exocytosis.

P42945	UTP10_YEAST	U3 small nucleolar RNA-associated protein 10	17652137	Roles of the HEAT repeat proteins Utp10 and Utp20 in 40S ribosome maturation.

Q62471	VNS1_MOUSE	Vomeronasal secretory protein 1	7813422	Possible pheromone-carrier function of two lipocalin proteins in the vomeronasal organ.

O94619	YBKA_SCHPO	LisH domain-containing protein C1289.10c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O00291	HIP1_HUMAN	Huntingtin-interacting protein 1	11532990	The huntingtin interacting protein HIP1 is a clathrin and alpha- adaptin-binding protein involved in receptor-mediated endocytosis.

Q9BXP2	S12A9_HUMAN	Solute carrier family 12 member 9	10871601	Cloning and functional characterization of a cation-Cl-cotransporter- interacting protein.

P56603	SCAM1_RAT	Secretory carrier-associated membrane protein 1	10777571	SCAMP1 function in endocytosis.

P31384	CCR4_YEAST	Glucose-repressible alcohol dehydrogenase transcriptional effector	11239395	The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiae.

P47175	HMS2_YEAST	Probable transcription factor HMS2	9832522	Regulators of pseudohyphal differentiation in Saccharomyces cerevisiae identified through multicopy suppressor analysis in ammonium permease mutant strains.

Q06410	ATG17_YEAST	Autophagy-related protein 17	10995454	Tor-mediated induction of autophagy via an Apg1 protein kinase complex.

Q9D2E1	TSSK3_MOUSE	Testis-specific serine/threonine-protein kinase 3	11597141	Cloning and chromosomal localization of a gene encoding a novel serine/threonine kinase belonging to the subfamily of testis-specific kinases.

O54693	EDA_MOUSE	Ectodysplasin-A	10534613	Ectodysplasin, a protein required for epithelial morphogenesis, is a novel TNF homologue and promotes cell-matrix adhesion.

P26715	NKG2A_HUMAN	NKG2-A/NKG2-B type II integral membrane protein	2007850	DNA sequence analysis of NKG2, a family of related cDNA clones encoding type II integral membrane proteins on human natural killer cells.

Q9USL4	NUP61_SCHPO	Nucleoporin nup61	15116432	Identification of genes encoding putative nucleoporins and transport factors in the fission yeast Schizosaccharomyces pombe: a deletion analysis.

P30260	CDC27_HUMAN	Cell division cycle protein 27 homolog	16364912	Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C.

Q62840	AMBN_RAT	Ameloblastin	8797107	A novel gene expressed in rat ameloblasts codes for proteins with cell binding domains.

D0VWV4	C560_PIG	Succinate dehydrogenase cytochrome b560 subunit, mitochondrial	17480203	Preliminary molecular characterization and crystallization of mitochondrial respiratory complex II from porcine heart.

Q9LME4	P2C09_ARATH	Probable protein phosphatase 2C 9	18564962	A novel protein phosphatase indirectly regulates phytochrome- interacting factor 3 via phytochrome.

P87161	RHGB_ASPNG	Rhamnogalacturonase B	9212401	Cloning and characterization of two rhamnogalacturonan hydrolase genes from Aspergillus niger.

Q9Y6R0	NUMBL_HUMAN	Numb-like protein	9303539	Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction module.

Q9FLB1	PYL5_ARATH	Abscisic acid receptor PYL5	19407143	Regulators of PP2C phosphatase activity function as abscisic acid sensors.

Q9Z130	HNRDL_MOUSE	Heterogeneous nuclear ribonucleoprotein D-like	10717477	Molecular characterization of a mouse heterogeneous nuclear ribonucleoprotein D-like protein JKTBP and its tissue-specific expression.

Q12359	ATO3_YEAST	Ammonia transport outward protein 3	12429834	Ammonia pulses and metabolic oscillations guide yeast colony development.

P61316	LOLA_ECOLI	Outer-membrane lipoprotein carrier protein	7628437	A novel periplasmic carrier protein involved in the sorting and transport of Escherichia coli lipoproteins destined for the outer membrane.

Q92828	COR2A_HUMAN	Coronin-2A	8985118	cDNA cloning of a novel WD repeat protein mapping to the 9q22.3 chromosomal region.

Q9W4S7	MYC_DROME	Myc protein	9037036	Drosophila Myc is oncogenic in mammalian cells and plays a role in the diminutive phenotype.

Q9NS86	LANC2_HUMAN	LanC-like protein 2	11762191	Molecular cloning, characterization, and tissue-specific expression of human LANCL2, a novel member of the LanC-like protein family.

P21240	RUBB_ARATH	RuBisCO large subunit-binding protein subunit beta, chloroplastic	12766230	Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.

Q9HEQ9	TCG1_SCHPO	Single-stranded TG1-3 DNA-binding protein	12519786	Exposure of single-stranded telomeric DNA causes G2/M cell cycle arrest in Saccharomyces cerevisiae.

P54397	FKB39_DROME	39 kDa FK506-binding nuclear protein	7538962	FKBP39, a Drosophila member of a family of proteins that bind the immunosuppressive drug FK506.

P63024	VAMP3_MOUSE	Vesicle-associated membrane protein 3	20057356	Identification of a novel Bves function: regulation of vesicular transport.

P53551	H1_YEAST	Histone H1	9046096	Histone H1 in Saccharomyces cerevisiae.

Q15911	ZFHX3_HUMAN	Zinc finger homeobox protein 3	1719379	A human alpha-fetoprotein enhancer-binding protein, ATBF1, contains four homeodomains and seventeen zinc fingers.

Q90ZH9	S17AB_XENLA	Transcription factor Sox-17-alpha-B	12591603	Redundant early and overlapping larval roles of Xsox17 subgroup genes in Xenopus endoderm development.

Q20561	HLH13_CAEEL	Helix-loop-helix protein 13	19103192	Combined informatic and expression screen identifies the novel DAF-16 target HLH-13.

P89105	CTR9_YEAST	RNA polymerase-associated protein CTR9	12242279	RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach.

P40344	ATG3_YEAST	Autophagy-related protein 3	14562095	Global analysis of protein localization in budding yeast.

O94855	SC24D_HUMAN	Protein transport protein Sec24D	10329445	A family of mammalian proteins homologous to yeast Sec24p.

P24521	ERG8_YEAST	Phosphomevalonate kinase	1846667	Cloning and characterization of ERG8, an essential gene of Saccharomyces cerevisiae that encodes phosphomevalonate kinase.

Q8CGN4	BCOR_MOUSE	BCL-6 corepressor	12776190	The mixed lineage leukemia fusion partner AF9 binds specific isoforms of the BCL-6 corepressor.

Q9XTN2	IRS1_DROME	Insulin receptor substrate 1	15890189	Insulin signaling is necessary for vitellogenesis in Drosophila melanogaster independent of the roles of juvenile hormone and ecdysteroids: female sterility of the chico1 insulin signaling mutation is autonomous to the ovary.

Q0DC89	MSRB1_ORYSJ	Peptide methionine sulfoxide reductase B1, chloroplastic	19415325	OsMSRA4.1 and OsMSRB1.1, two rice plastidial methionine sulfoxide reductases, are involved in abiotic stress responses.

P25604	STP22_YEAST	Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease	16615894	Structural and functional organization of the ESCRT-I trafficking complex.

Q42384	PRL1_ARATH	Protein pleiotropic regulatory locus 1	18223036	Characterization of Arabidopsis and rice DWD proteins and their roles as substrate receptors for CUL4-RING E3 ubiquitin ligases.

O08808	DIAP1_MOUSE	Protein diaphanous homolog 1	19350017	SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta1-integrin.

P27197	AURB_CHLAA	Auracyanin-B	12589566	A thin-film electrochemical study of the 'blue' copper proteins, auracyanin A and auracyanin B, from the photosynthetic bacterium Chloroflexus aurantiacus: the reduction potential as a function of pH.

P75853	SSUA_ECOLI	Putative aliphatic sulfonates-binding protein	10506196	The Escherichia coli ssuEADCB gene cluster is required for the utilization of sulfur from aliphatic sulfonates and is regulated by the transcriptional activator Cbl.

Q91WL8	WWOX_MOUSE	WW domain-containing oxidoreductase	18487609	The WWOX tumor suppressor is essential for postnatal survival and normal bone metabolism.

Q5BJF2	TMM97_HUMAN	Transmembrane protein 97	19583955	Identification of cholesterol-regulating genes by targeted RNAi screening.

P06313	KV403_HUMAN	Ig kappa chain V-IV region JI	2997712	Subgroup IV of human immunoglobulin K light chains is encoded by a single germline gene.

P83511	LEC_DELRE	Lectin	12168698	Biochemical characterization of a lectin from Delonix regia seeds.

Q9SRT3	CSLC6_ARATH	Probable xyloglucan glycosyltransferase 6	16618929	Mapping the Arabidopsis organelle proteome.

Q9SIZ3	PMTN_ARATH	Probable methyltransferase PMT23	16618929	Mapping the Arabidopsis organelle proteome.

Q01112	CDC42_SCHPO	Cell division control protein 42 homolog	12972551	Gef1p and Scd1p, the Two GDP-GTP exchange factors for Cdc42p, form a ring structure that shrinks during cytokinesis in Schizosaccharomyces pombe.

P19237	TNNI1_HUMAN	Troponin I, slow skeletal muscle	2365354	cDNA sequence, tissue-specific expression, and chromosomal mapping of the human slow-twitch skeletal muscle isoform of troponin I.

P87245	KMS1_SCHPO	Karyogamy meiotic segregation protein 1	9150257	A novel fission yeast gene, kms1+, is required for the formation of meiotic prophase-specific nuclear architecture.

O04719	P2C77_ARATH	Protein phosphatase 2C 77	15923322	Heat stress phenotypes of Arabidopsis mutants implicate multiple signaling pathways in the acquisition of thermotolerance.

P46640	KNAT2_ARATH	Homeobox protein knotted-1-like 2	17873098	The Arabidopsis BEL1-LIKE HOMEODOMAIN proteins SAW1 and SAW2 act redundantly to regulate KNOX expression spatially in leaf margins.

Q9S9P6	FORT_ARATH	Flavonol-3-O-glucoside L-rhamnosyltransferase	12900416	UGT73C6 and UGT78D1, glycosyltransferases involved in flavonol glycoside biosynthesis in Arabidopsis thaliana.

O15327	INP4B_HUMAN	Type II inositol-3,4-bisphosphate 4-phosphatase	9295334	The cDNA cloning and characterization of inositol polyphosphate 4- phosphatase type II. Evidence for conserved alternative splicing in the 4-phosphatase family.

P31385	DEP1_YEAST	Transcriptional regulatory protein DEP1	16286008	Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex.

Q8K485	KCD11_MOUSE	BTB/POZ domain-containing protein KCTD11	12186855	REN: a novel, developmentally regulated gene that promotes neural cell differentiation.

Q9Y6E7	SIRT4_HUMAN	NAD-dependent ADP-ribosyltransferase sirtuin-4	16959573	SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells.

Q9V730	EXT1_DROME	Exostosin-1	10644674	Structural analysis of glycosaminoglycans in Drosophila and Caenorhabditis elegans and demonstration that tout-velu, a Drosophila gene related to EXT tumor suppressors, affects heparan sulfate in vivo.

Q9Z200	SH2B2_RAT	SH2B adapter protein 2	9856458	Identification and characterization of novel substrates of Trk receptors in developing neurons.

Q96RL1	UIMC1_HUMAN	BRCA1-A complex subunit RAP80	19202061	The Rap80-BRCC36 de-ubiquitinating enzyme complex antagonizes RNF8- Ubc13-dependent ubiquitination events at DNA double strand breaks.

Q4PSU4	AGL61_ARATH	Agamous-like MADS-box protein AGL61	18713950	The MADS domain protein DIANA acts together with AGAMOUS-LIKE80 to specify the central cell in Arabidopsis ovules.

Q9FJP6	PUB38_ARATH	U-box domain-containing protein 38	14657406	A large complement of the predicted Arabidopsis ARM repeat proteins are members of the U-box E3 ubiquitin ligase family.

Q86V81	THOC4_HUMAN	THO complex subunit 4	15833825	Linking transcriptional elongation and messenger RNA export to metastatic breast cancers.

P60566	FIXA_ECOLI	Protein fixA	12081978	The fixA and fixB genes are necessary for anaerobic carnitine reduction in Escherichia coli.

P50750	CDK9_HUMAN	Cell division protein kinase 9	8170997	PITALRE, a nuclear CDC2-related protein kinase that phosphorylates the retinoblastoma protein in vitro.

P08172	ACM2_HUMAN	Muscarinic acetylcholine receptor M2	3037705	Identification of a family of muscarinic acetylcholine receptor genes.

P46965	SPC1_YEAST	Signal peptidase complex subunit SPC1	10921929	Interactions between Spc2p and other components of the endoplasmic reticulum translocation sites of the yeast Saccharomyces cerevisiae.

Q86Z14	KLOTB_HUMAN	Beta-klotho	19117008	Different roles of N- and C- termini in the functional activity of FGF21.

Q9NPP4	NLRC4_HUMAN	NLR family CARD domain-containing protein 4	11472070	CLAN, a novel human CED-4-like gene.

Q6IVW0	IFT57_DANRE	Intraflagellar transport protein 57 homolog	18056639	A role for the inositol kinase Ipk1 in ciliary beating and length maintenance.

Q96T54	KCNKH_HUMAN	Potassium channel subfamily K member 17	11248242	Characterization of TASK-4, a novel member of the pH-sensitive, two- pore domain potassium channel family.

Q08369	GATA4_MOUSE	Transcription factor GATA-4	8455608	Mouse GATA-4: a retinoic acid-inducible GATA-binding transcription factor expressed in endodermally derived tissues and heart.

Q12515	PAR32_YEAST	Protein PAR32	14562095	Global analysis of protein localization in budding yeast.

O96185	YPF08_PLAF7	Uncharacterized protein PFB0460c	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

Q8AYG3	TTK_DANRE	Dual specificity protein kinase Ttk	15231734	Germ cell aneuploidy in zebrafish with mutations in the mitotic checkpoint gene mps1.

O81850	IRT2_ARATH	Fe(2+) transport protein 2	11389759	Arabidopsis IRT2 gene encodes a root-periphery iron transporter.

Q60974	NCOR1_MOUSE	Nuclear receptor corepressor 1	9702189	SAP30, a component of the mSin3 corepressor complex involved in N- CoR-mediated repression by specific transcription factors.

P53889	FMP41_YEAST	Uncharacterized mitochondrial hydrolase FMP41	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q9Z2D6	MECP2_MOUSE	Methyl-CpG-binding protein 2	15034150	The major form of MeCP2 has a novel N-terminus generated by alternative splicing.

Q99MB3	TM2D1_MOUSE	TM2 domain-containing protein 1	11278849	Beta-amyloid peptide-induced apoptosis regulated by a novel protein containing a G protein activation module.

Q9JLI4	NCOA6_RAT	Nuclear receptor coactivator 6	10866662	A new family of nuclear receptor coregulators that integrates nuclear receptor signaling through CBP.

Q9NS56	TOPRS_HUMAN	E3 ubiquitin-protein ligase Topors	10352183	Interaction between human topoisomerase I and a novel RING finger/arginine-serine protein.

P09417	DHPR_HUMAN	Dihydropteridine reductase	3033643	Structure and expression of human dihydropteridine reductase.

Q8IQ72	GR65A_DROME	Putative chemosensory receptor 65a	14608037	Molecular evolution of the insect chemoreceptor gene superfamily in Drosophila melanogaster.

P69771	DID2_YEAST	Vacuolar protein-sorting-associated protein 46	11029042	The Doa4 deubiquitinating enzyme is functionally linked to the vacuolar protein-sorting and endocytic pathways.

P21275	BMP4_MOUSE	Bone morphogenetic protein 4	8358941	Gene cloning and expression of a bone morphogenetic protein derived from a murine osteosarcoma.

Q3UNW5	TF2L1_MOUSE	Transcription factor CP2-like protein 1	11073954	CRTR-1, a developmentally regulated transcriptional repressor related to the CP2 family of transcription factors.

Q923W9	ADA33_MOUSE	Disintegrin and metalloproteinase domain-containing protein 33	11814695	Identification and characterization of novel mouse and human ADAM33s with potential metalloprotease activity.

Q9HCJ1	ANKH_HUMAN	Progressive ankylosis protein homolog	10894769	Role of the mouse ank gene in control of tissue calcification and arthritis.

Q6ZMZ3	SYNE3_HUMAN	Nesprin-3	18396275	Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness.

Q22875	SHOC2_CAEEL	Leucine-rich repeat protein soc-2	9674433	SUR-8, a conserved Ras-binding protein with leucine-rich repeats, positively regulates Ras-mediated signaling in C. elegans.

P35177	SPT7_YEAST	Transcriptional activator SPT7	12446794	The novel SLIK histone acetyltransferase complex functions in the yeast retrograde response pathway.

P60881	SNP25_RAT	Synaptosomal-associated protein 25	11438518	Direct interaction of the Rab3 effector RIM with Ca2+ channels, SNAP- 25, and synaptotagmin.

Q08695	MST1_DROHY	Axoneme-associated protein mst101(1)	8150205	The Drosophila hydei gene Dhmst101(1) encodes a testis-specific, repetitive, axoneme-associated protein with differential abundance in Y chromosomal deletion mutant flies.

Q99288	DET1_YEAST	Putative phosphoglycerate mutase DET1	19060182	Tritium suicide selection identifies proteins involved in the uptake and intracellular transport of sterols in Saccharomyces cerevisiae.

P34087	RPB7_YEAST	DNA-directed RNA polymerase II subunit RPB7	17056745	Nucleocytoplasmic shuttling of the Rpb4p and Rpb7p subunits of Saccharomyces cerevisiae RNA polymerase II by two pathways.

P39013	END3_YEAST	Actin cytoskeleton-regulatory complex protein END3	9234686	EH domain proteins Pan1p and End3p are components of a complex that plays a dual role in organization of the cortical actin cytoskeleton and endocytosis in Saccharomyces cerevisiae.

Q9P1P5	TAAR2_HUMAN	Trace amine-associated receptor 2	10684976	Cloning and characterization of additional members of the G protein- coupled receptor family.

P22002	CAC1C_RAT	Voltage-dependent L-type calcium channel subunit alpha-1C	15140941	Ca2+-binding protein-1 facilitates and forms a postsynaptic complex with Cav1.2 (L-type) Ca2+ channels.

P17707	DCAM_HUMAN	S-adenosylmethionine decarboxylase proenzyme	1917972	Amino acid residues necessary for putrescine stimulation of human S- adenosylmethionine decarboxylase proenzyme processing and catalytic activity.

Q9SJQ6	ROS1_ARATH	Protein ROS1	12526807	ROS1, a repressor of transcriptional gene silencing in Arabidopsis, encodes a DNA glycosylase/lyase.

O96000	NDUBA_HUMAN	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

P56277	MTCNB_HUMAN	Mature T-cell proliferation 1 neighbor protein	8361760	MTCP-1: a novel gene on the human chromosome Xq28 translocated to the T cell receptor alpha/delta locus in mature T cell proliferations.

Q07523	HAOX2_RAT	Hydroxyacid oxidase 2	15683236	Crystal structure analysis of recombinant rat kidney long chain hydroxy acid oxidase.

Q09969	BNIP3_CAEEL	NIP3 homolog	16380712	Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation.

P12755	SKI_HUMAN	Ski oncogene	12874272	Requirement of the co-repressor homeodomain-interacting protein kinase 2 for ski-mediated inhibition of bone morphogenetic protein- induced transcriptional activation.

P43121	MUC18_HUMAN	Cell surface glycoprotein MUC18	8378324	Genomic organization of the melanoma-associated glycoprotein MUC18: implications for the evolution of the immunoglobulin domains.

O81445	CNBL1_ARATH	Calcineurin B-like protein 1	17898163	A protein phosphorylation/dephosphorylation network regulates a plant potassium channel.

O00358	FOXE1_HUMAN	Forkhead box protein E1	12165566	A novel loss-of-function mutation in TTF-2 is associated with congenital hypothyroidism, thyroid agenesis and cleft palate.

O22446	HDA19_ARATH	Histone deacetylase 19	15994908	Role of an Arabidopsis AP2/EREBP-type transcriptional repressor in abscisic acid and drought stress responses.

P55786	PSA_HUMAN	Puromycin-sensitive aminopeptidase	9048733	Cloning of the human puromycin-sensitive aminopeptidase and evidence for expression in neurons.

P13186	KIN2_YEAST	Serine/threonine-protein kinase KIN2	8203145	Characterization of the KIN2 gene product in Saccharomyces cerevisiae and comparison between the kinase activities of p145KIN1 and p145KIN2.

Q8WVL7	ANR49_HUMAN	Ankyrin repeat domain-containing protein 49	11162141	Cloning and characterization of a potential transcriptional activator of human gamma-globin genes.

Q9P7R9	SYF1_SCHPO	Pre-mRNA-splicing factor syf1	10409726	Myb-related fission yeast cdc5p is a component of a 40S snRNP- containing complex and is essential for pre-mRNA splicing.

Q9M276	ATB12_ARATH	Homeobox-leucine zipper protein ATHB-12	15369784	Athb-12, a homeobox-leucine zipper domain protein from Arabidopsis thaliana, increases salt tolerance in yeast by regulating sodium exclusion.

P32447	ASF1_YEAST	Histone chaperone ASF1	16627621	Histone chaperone Asf1 is required for histone H3 lysine 56 acetylation, a modification associated with S phase in mitosis and meiosis.

Q94KI8	TPC1_ARATH	Two pore calcium channel protein 1	11577183	A putative two pore channel AtTPC1 mediates Ca(2+) flux in Arabidopsis leaf cells.

P49447	CY561_HUMAN	Cytochrome b561	7980462	Human cytochrome b561: a revised hypothesis for conformation in membranes which reconciles sequence and functional information.

P33941	YOJI_ECOLI	ABC transporter ATP-binding protein yojI	15866933	YojI of Escherichia coli functions as a microcin J25 efflux pump.

O94726	MNL1_SCHPO	ER degradation-enhancing alpha-mannosidase-like protein 1	16079177	Characterization of Schizosaccharomyces pombe ER alpha-mannosidase: a reevaluation of the role of the enzyme on ER-associated degradation.

Q9VC45	ASP_DROME	Protein abnormal spindle	15242765	The abnormal spindle protein is required for germ cell mitosis and oocyte differentiation during Drosophila oogenesis.

Q1L8L9	KAD2_DANRE	Adenylate kinase 2, mitochondrial	19043417	Reticular dysgenesis (aleukocytosis) is caused by mutations in the gene encoding mitochondrial adenylate kinase 2.

Q8L4Y5	ARP7_ARATH	Actin-related protein 7	16040647	Arabidopsis ARP7 is an essential actin-related protein required for normal embryogenesis, plant architecture, and floral organ abscission.

P42773	CDN2C_HUMAN	Cyclin-dependent kinase 4 inhibitor C	8001816	Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function.

Q54QG0	PGFB_DICDI	Bifunctional glycosyltransferase pgtA	12244067	A bifunctional diglycosyltransferase forms the Fucalpha1,2Galbeta1,3- disaccharide on Skp1 in the cytoplasm of dictyostelium.

Q06497	ANT1_YEAST	Peroxisomal adenine nucleotide transporter 1	11390660	Identification of a peroxisomal ATP carrier required for medium-chain fatty acid beta-oxidation and normal peroxisome proliferation in Saccharomyces cerevisiae.

P47979	ZFS1_SCHPO	Zinc finger protein zfs1	16273369	Moc3, a novel Zn finger type protein involved in sexual development, ascus formation, and stress response of Schizosaccharomyces pombe.

O59701	CYSK1_SCHPO	Cysteine synthase 1	14981292	Characterization of two genes encoding putative cysteine synthase required for cysteine biosynthesis in Schizosaccharomyces pombe.

P10610	CP2G1_RAT	Cytochrome P450 2G1	2708343	Olfactory-specific cytochrome P-450. cDNA cloning of a novel neuroepithelial enzyme possibly involved in chemoreception.

P13649	PYRF_CANAL	Orotidine 5'-phosphate decarboxylase	2574635	Sequence and transcript analysis of the C. albicans URA3 gene encoding orotidine-5'-phosphate decarboxylase.

Q9UN37	VPS4A_HUMAN	Vacuolar protein sorting-associated protein 4A	17853893	Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis.

O95297	MPZL1_HUMAN	Myelin protein zero-like protein 1	10681522	Dissecting the interaction of SHP-2 with PZR, an immunoglobulin family protein containing immunoreceptor tyrosine-based inhibitory motifs.

P31755	OCH1_YEAST	Initiation-specific alpha-1,6-mannosyltransferase	8253757	Structure of the N-linked oligosaccharides that show the complete loss of alpha-1,6-polymannose outer chain from och1, och1 mnn1, and och1 mnn1 alg3 mutants of Saccharomyces cerevisiae.

Q40687	GBB_ORYSJ	Guanine nucleotide-binding protein subunit beta	8665097	Molecular cloning and characterization of a cDNA for the beta subunit of a G protein from rice.

P29033	CXB2_HUMAN	Gap junction beta-2 protein	1324944	Transcriptional downregulation of gap-junction proteins blocks junctional communication in human mammary tumor cell lines.

O80536	PIF3_ARATH	Transcription factor PIF3	9845368	PIF3, a phytochrome-interacting factor necessary for normal photoinduced signal transduction, is a novel basic helix-loop-helix protein.

Q07376	MCH1_YEAST	Probable transporter MCH1	11536335	The putative monocarboxylate permeases of the yeast Saccharomyces cerevisiae do not transport monocarboxylic acids across the plasma membrane.

Q39026	MPK6_ARATH	Mitogen-activated protein kinase 6	12220631	Different protein kinase families are activated by osmotic stresses in Arabidopsis thaliana cell suspensions. Involvement of the MAP kinases AtMPK3 and AtMPK6.

P42523	TGRC1_DICDI	Tiger protein C1	19285397	Polymorphic members of the lag gene family mediate kin discrimination in Dictyostelium.

P62854	RS26_HUMAN	40S ribosomal protein S26	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

O75486	SUPT3_HUMAN	Transcription initiation protein SPT3 homolog	11564863	Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage- binding factors in vivo.

Q9FY48	KEG_ARATH	E3 ubiquitin-protein ligase KEG	18815384	Powdery mildew resistance conferred by loss of the ENHANCED DISEASE RESISTANCE1 protein kinase is suppressed by a missense mutation in KEEP ON GOING, a regulator of abscisic acid signaling.

Q13203	MYBPH_HUMAN	Myosin-binding protein H	8486381	Human myosin-binding protein H (MyBP-H): complete primary sequence, genomic organization, and chromosomal localization.

Q08968	FMP40_YEAST	UPF0061 protein FMP40	14562095	Global analysis of protein localization in budding yeast.

O55170	SOX10_RAT	Transcription factor SOX-10	9412504	Sox10, a novel transcriptional modulator in glial cells.

O43679	LDB2_HUMAN	LIM domain-binding protein 2	9853615	Selection system for genes encoding nuclear-targeted proteins.

P05231	IL6_HUMAN	Interleukin-6	3491322	Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin.

P38231	FMP23_YEAST	Protein FMP23, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

P29310	1433Z_DROME	14-3-3 protein zeta	18256197	In vivo regulation of Yorkie phosphorylation and localization.

P20271	HM14_CAEEL	Homeobox protein ceh-14	10774727	The LIM homeobox gene ceh-14 confers thermosensory function to the AFD neurons in Caenorhabditis elegans.

Q9WVC5	TRPC7_MOUSE	Short transient receptor potential channel 7	10488066	Molecular and functional characterization of a novel mouse transient receptor potential protein homologue TRP7. Ca(2+)-permeable cation channel that is constitutively activated and enhanced by stimulation of G protein-coupled receptor.

P13587	ATN1_YEAST	Sodium transport ATPase 1	8612770	Multiple transduction pathways regulate the sodium-extrusion gene PMR2/ENA1 during salt stress in yeast.

Q9LYN2	FRI3_ARATH	Ferritin-3, chloroplastic	11672431	Structure and differential expression of the four members of the Arabidopsis thaliana ferritin gene family.

P38210	LDB7_YEAST	Chromatin structure-remodeling complex protein RSC14	16204215	The RSC chromatin remodeling complex bears an essential fungal- specific protein module with broad functional roles.

Q9P7S6	SNF30_SCHPO	SWI/SNF chromatin-remodeling complex subunit snf30	18622392	Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast.

P17221	FEM1_CAEEL	Sex-determining protein fem-1	17609115	A CUL-2 ubiquitin ligase containing three FEM proteins degrades TRA-1 to regulate C. elegans sex determination.

Q16633	OBF1_HUMAN	POU domain class 2-associating factor 1	7859290	OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer- binding proteins.

P25028	FSYA_DROME	Mitosis initiation protein fs(1)Ya	1986869	The Drosophila maternal-effect gene fs(1)Ya encodes a cell cycle- dependent nuclear envelope component required for embryonic mitosis.

P53924	DMA2_YEAST	E3 ubiquitin-protein ligase DMA2	18202552	Yeast Chfr homologs retard cell cycle at G1 and G2/M via Ubc4 and Ubc13/Mms2-dependent ubiquitination.

Q9SMZ4	AASS_ARATH	Alpha-aminoadipic semialdehyde synthase	11080311	Characterization of the two saccharopine dehydrogenase isozymes of lysine catabolism encoded by the single composite AtLKR/SDH locus of Arabidopsis.

Q15406	NR6A1_HUMAN	Nuclear receptor subfamily 6 group A member 1	9134503	Cloning of the human orphan receptor germ cell nuclear factor/retinoid receptor-related testis-associated receptor and its differential regulation during embryonal carcinoma cell differentiation.

O13776	YE9G_SCHPO	UPF0663 protein C17A5.16	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12873	CHD3_HUMAN	Chromodomain-helicase-DNA-binding protein 3	7560064	Molecular analysis of a major antigenic region of the 240 kD protein of Mi-2 autoantigen.

Q9UPN6	RBM16_HUMAN	RNA-binding protein 16	18550522	Snapshots of the RNA processing factor SCAF8 bound to different phosphorylated forms of the carboxyl-terminal domain of RNA polymerase II.

P53252	PIL1_YEAST	Sphingolipid long chain base-responsive protein PIL1	15016821	Pil1p and Lsp1p negatively regulate the 3-phosphoinositide-dependent protein kinase-like kinase Pkh1p and downstream signaling pathways Pkc1p and Ypk1p.

O96011	PX11B_HUMAN	Peroxisomal membrane protein 11B	10704444	PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis.

Q15526	SURF1_HUMAN	Surfeit locus protein 1	9843204	SURF1, encoding a factor involved in the biogenesis of cytochrome c oxidase, is mutated in Leigh syndrome.

P43298	TMK1_ARATH	Probable receptor protein kinase TMK1	1332795	The TMK1 gene from Arabidopsis codes for a protein with structural and biochemical characteristics of a receptor protein kinase.

P41834	UFE1_YEAST	Syntaxin UFE1	9214619	A novel SNARE complex implicated in vesicle fusion with the endoplasmic reticulum.

O00548	DLL1_HUMAN	Delta-like protein 1	10079256	Human ligands of the Notch receptor.

Q9XI07	SWI3C_ARATH	SWI/SNF complex subunit SWI3C	12140326	AtSWI3B, an Arabidopsis homolog of SWI3, a core subunit of yeast Swi/Snf chromatin remodeling complex, interacts with FCA, a regulator of flowering time.

Q9DAP7	ASF1B_MOUSE	Histone chaperone ASF1B	12842904	Transcription initiation factor IID-interactive histone chaperone CIA-II implicated in mammalian spermatogenesis.

O94864	ST65G_HUMAN	STAGA complex 65 subunit gamma	11564863	Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage- binding factors in vivo.

P38316	ATG12_YEAST	Ubiquitin-like protein ATG12	11897782	Formation of the approximately 350-kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast.

P55073	IOD3_HUMAN	Type III iodothyronine deiodinase	7593630	Type 3 iodothyronine deiodinase: cloning, in vitro expression, and functional analysis of the placental selenoenzyme.

P46063	RECQ1_HUMAN	ATP-dependent DNA helicase Q1	15886194	RECQ1 helicase interacts with human mismatch repair factors that regulate genetic recombination.

Q04636	POB3_YEAST	FACT complex subunit POB3	12242279	RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach.

P62491	RB11A_HUMAN	Ras-related protein Rab-11A	12470645	Rab11-FIP4 interacts with Rab11 in a GTP-dependent manner and its overexpression condenses the Rab11 positive compartment in HeLa cells.

P47113	BFA1_YEAST	Mitotic check point protein BFA1	10220406	Bifurcation of the mitotic checkpoint pathway in budding yeast.

P05113	IL5_HUMAN	Interleukin-5	3498940	Molecular cloning, nucleotide sequence, and expression of the gene encoding human eosinophil differentiation factor (interleukin 5).

Q92793	CBP_HUMAN	CREB-binding protein	11568182	Interaction of EVI1 with cAMP-responsive element-binding protein- binding protein (CBP) and p300/CBP-associated factor (P/CAF) results in reversible acetylation of EVI1 and in co-localization in nuclear speckles.

Q12378	RTR2_YEAST	RNA polymerase II subunit B1 CTD phosphatase RTR2	14562095	Global analysis of protein localization in budding yeast.

Q1MTN3	PIC1_SCHPO	Inner centromere protein-related protein pic1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9H5Q4	TFB2M_HUMAN	Dimethyladenosine transferase 2, mitochondrial	12068295	Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA.

P85975	VMPAR_HIPPR	Zinc metalloproteinase partitagin	17555860	'Partitagin' a hemorrhagic metalloprotease from Hippasa partita spider venom: role in tissue necrosis.

Q63258	ITA7_RAT	Integrin alpha-7	1315319	H36-alpha 7 is a novel integrin alpha chain that is developmentally regulated during skeletal myogenesis.

P98153	IDD_HUMAN	Integral membrane protein DGCR2/IDD	7655455	Isolation of a gene encoding an integral membrane protein from the vicinity of a balanced translocation breakpoint associated with DiGeorge syndrome.

Q5HYA8	MKS3_HUMAN	Meckelin	17185389	The Meckel-Gruber syndrome proteins MKS1 and meckelin interact and are required for primary cilium formation.

P0ABD5	ACCA_ECOLI	Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha	1355089	The genes encoding the two carboxyltransferase subunits of Escherichia coli acetyl-CoA carboxylase.

P60228	EIF3E_HUMAN	Eukaryotic translation initiation factor 3 subunit E	17581632	Reconstitution reveals the functional core of mammalian eIF3.

P30462	1B14_HUMAN	HLA class I histocompatibility antigen, B-14 alpha chain	2715640	Diversity and diversification of HLA-A,B,C alleles.

Q92556	ELMO1_HUMAN	Engulfment and cell motility protein 1	11595183	CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration.

P43254	COP1_ARATH	E3 ubiquitin-protein ligase COP1	10839542	Targeted destabilization of HY5 during light-regulated development of Arabidopsis.

Q9SMX3	VDAC2_ARATH	Mitochondrial outer membrane protein porin 2	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P70597	PE2R1_RAT	Prostaglandin E2 receptor EP1 subtype	8940129	Suppression of prostaglandin E receptor signaling by the variant form of EP1 subtype.

Q9USK8	AGS1_SCHPO	Cell wall alpha-1,3-glucan synthase ags1	17472966	Role of the synthase domain of Ags1p in cell wall {alpha}-glucan biosynthesis in fission yeast.

Q9VD83	BURS_DROME	Bursicon	15242619	Identification of the gene encoding bursicon, an insect neuropeptide responsible for cuticle sclerotization and wing spreading.

P32521	PAN1_YEAST	Actin cytoskeleton-regulatory complex protein PAN1	9234686	EH domain proteins Pan1p and End3p are components of a complex that plays a dual role in organization of the cortical actin cytoskeleton and endocytosis in Saccharomyces cerevisiae.

P13432	SMR1_RAT	SMR1 protein	9321881	A novel submandibular gland peptide protects against endotoxic and anaphylactic shock.

Q9P381	CDSH_SCHPO	Putative phosphatidate cytidylyltransferase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9C029	TRIM7_HUMAN	Tripartite motif-containing protein 7	11331580	The tripartite motif family identifies cell compartments.

Q9Y6H3	ATP23_HUMAN	Mitochondrial inner membrane protease ATP23 homolog	10219089	Isolation of Ku70-binding proteins (KUBs).

Q86W92	LIPB1_HUMAN	Liprin-beta-1	9624153	Liprins, a family of LAR transmembrane protein-tyrosine phosphatase- interacting proteins.

Q12216	SIZ2_YEAST	E3 SUMO-protein ligase SIZ2	12761287	Comparative analysis of yeast PIAS-type SUMO ligases in vivo and in vitro.

Q08550	MPC54_YEAST	Meiotic plaque component protein 54	11742972	Prospore membrane formation linked to the leading edge protein (LEP) coat assembly.

P06100	NOT2_YEAST	General negative regulator of transcription subunit 2	10490603	The CCR4 and CAF1 proteins of the CCR4-NOT complex are physically and functionally separated from NOT2, NOT4, and NOT5.

P54683	TAGB_DICDI	Serine protease/ABC transporter B family protein tagB	7744252	A multidrug resistance transporter/serine protease gene is required for prestalk specialization in Dictyostelium.

P12034	FGF5_HUMAN	Fibroblast growth factor 5	3211147	The human FGF-5 oncogene encodes a novel protein related to fibroblast growth factors.

Q8IUC6	TCAM1_HUMAN	TIR domain-containing adapter molecule 1	12721283	TIRP, a novel Toll/interleukin-1 receptor (TIR) domain-containing adapter protein involved in TIR signaling.

P23381	SYWC_HUMAN	Tryptophanyl-tRNA synthetase, cytoplasmic	1761529	Interferon induces tryptophanyl-tRNA synthetase expression in human fibroblasts.

Q8GWT4	ANM5_ARATH	Protein arginine N-methyltransferase 5	17363895	SKB1-mediated symmetric dimethylation of histone H4R3 controls flowering time in Arabidopsis.

O02326	CFI1_CAEEL	AT-rich interactive domain-containing protein cfi-1	11959845	Control of neuronal subtype identity by the C. elegans ARID protein CFI-1.

P07342	ILVB_YEAST	Acetolactate synthase catalytic subunit, mitochondrial	10213630	Expression, purification, characterization, and reconstitution of the large and small subunits of yeast acetohydroxyacid synthase.

P21812	MCPT4_MOUSE	Mast cell protease 4	12900518	The chymase, mouse mast cell protease 4, constitutes the major chymotrypsin-like activity in peritoneum and ear tissue. A role for mouse mast cell protease 4 in thrombin regulation and fibronectin turnover.

P02407	RS17A_YEAST	40S ribosomal protein S17-A	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q6ZPS2	CRNS1_MOUSE	Carnosine synthase 1	20097752	Molecular identification of carnosine synthase as ATP-grasp domain- containing protein 1 (ATPGD1).

Q03370	PEX29_YEAST	Peroxisomal membrane protein PEX29	12707309	YHR150w and YDR479c encode peroxisomal integral membrane proteins involved in the regulation of peroxisome number, size, and distribution in Saccharomyces cerevisiae.

Q54RF4	CBP4A_DICDI	Calcium-binding protein 4a	10771103	Characterization and hetereologous expression of cDNAs encoding two novel closely related Ca(2+)-binding proteins in Dictyostelium discoideum.

Q62952	DPYL3_RAT	Dihydropyrimidinase-related protein 3	8815901	A family of rat CRMP genes is differentially expressed in the nervous system.

Q28283	TRIB2_CANFA	Tribbles homolog 2	9342215	Characterization of a phosphoprotein whose mRNA is regulated by the mitogenic pathways in dog thyroid cells.

Q9UHF7	TRPS1_HUMAN	Zinc finger transcription factor Trps1	12885770	The RING finger protein RNF4, a co-regulator of transcription, interacts with the TRPS1 transcription factor.

Q9VBL6	MS57A_DROME	Accessory gland-specific peptide 57Da	7711745	Structure and regulation of a gene cluster for male accessory gland transcripts in Drosophila melanogaster.

Q9H244	P2Y12_HUMAN	P2Y purinoceptor 12	11196645	Identification of the platelet ADP receptor targeted by antithrombotic drugs.

Q9DGB6	TLR22_CHICK	Toll-like receptor 2 type-2	11590137	Molecular cloning and functional characterization of chicken Toll- like receptors. A single chicken Toll covers multiple molecular patterns.

P27305	GLUQ_ECOLI	Glutamyl-Q tRNA(Asp) synthetase	15003446	The Escherichia coli YadB gene product reveals a novel aminoacyl-tRNA synthetase like activity.

P30793	GCH1_HUMAN	GTP cyclohydrolase 1	16696853	A yeast 2-hybrid analysis of human GTP cyclohydrolase I protein interactions.

Q13733	AT1A4_HUMAN	Sodium/potassium-transporting ATPase subunit alpha-4	7809153	A putative fourth Na+,K(+)-ATPase alpha-subunit gene is expressed in testis.

P24054	SPRL1_RAT	SPARC-like protein 1	1690015	Molecular cloning of SC1: a putative brain extracellular matrix glycoprotein showing partial similarity to osteonectin/BM40/SPARC.

P53030	RL1_YEAST	60S ribosomal protein L1	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q7TME2	SPAG5_MOUSE	Sperm-associated antigen 5	12893248	Expression and promoter analysis of mouse mastrin gene.

Q9UMS4	PRP19_HUMAN	Pre-mRNA-processing factor 19	16332694	SNEV is an evolutionarily conserved splicing factor whose oligomerization is necessary for spliceosome assembly.

P83143	AFP2L_MALPA	Antifungal protein 2 large subunit	11118343	Potent heterologous antifungal proteins from cheeseweed (Malva parviflora).

O94905	ERLN2_HUMAN	Erlin-2	16835267	Erlin-1 and erlin-2 are novel members of the prohibitin family of proteins that define lipid-raft-like domains of the ER.

Q92874	DNSL2_HUMAN	Deoxyribonuclease-1-like 2	9205125	Identification, localization, and expression of two novel human genes similar to deoxyribonuclease I.

P00363	FRDA_ECOLI	Fumarate reductase flavoprotein subunit	10373108	Structure of the Escherichia coli fumarate reductase respiratory complex.

P28676	GRAN_HUMAN	Grancalcin	11717497	Structure of Ca(2+)-loaded human grancalcin.

P78545	ELF3_HUMAN	ETS-related transcription factor Elf-3	15075319	Positive and negative modulation of the transcriptional activity of the ETS factor ESE-1 through interaction with p300, CREB-binding protein, and Ku 70/86.

P40473	POG1_YEAST	Transcriptional acticator POG1	12464632	Complex transcriptional circuitry at the G1/S transition in Saccharomyces cerevisiae.

O94901	SUN1_HUMAN	SUN domain-containing protein 1	19933576	Mammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processes.

P0C2I0	RL20_YEAST	60S ribosomal protein L20	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

P00338	LDHA_HUMAN	L-lactate dehydrogenase A chain	2334430	Molecular characterization of genetic mutation in human lactate dehydrogenase-A (M) deficiency.

Q99714	HCD2_HUMAN	3-hydroxyacyl-CoA dehydrogenase type-2	9338779	An intracellular protein that binds amyloid-beta peptide and mediates neurotoxicity in Alzheimer's disease.

P47171	HIR3_YEAST	Histone transcription regulator 3	9001207	Hir1p and Hir2p function as transcriptional corepressors to regulate histone gene transcription in the Saccharomyces cerevisiae cell cycle.

Q9UGU5	HMGX4_HUMAN	HMG domain-containing protein 4	10329004	TOM1 genes map to human chromosome 22q13.1 and mouse chromosome 8C1 and encode proteins similar to the endosomal proteins HGS and STAM.

P35556	FBN2_HUMAN	Fibrillin-2	7493032	Fibrillin-2 (FBN2) mutations result in the Marfan-like disorder, congenital contractural arachnodactyly.

Q60848	HELLS_MOUSE	Lymphocyte-specific helicase	10781083	Lsh, an SNF2/helicase family member, is required for proliferation of mature T lymphocytes.

Q86VS8	HOOK3_HUMAN	Protein Hook homolog 3	18799622	An FTS/Hook/p107(FHIP) complex interacts with and promotes endosomal clustering by the homotypic vacuolar protein sorting complex.

P04819	DNLI1_YEAST	DNA ligase 1	10531002	The yeast CDC9 gene encodes both a nuclear and a mitochondrial form of DNA ligase I.

Q9UKG4	S13A4_HUMAN	Solute carrier family 13 member 4	10535998	Molecular cloning and functional analysis of SUT-1, a sulfate transporter from human high endothelial venules.

O14047	PPK11_SCHPO	Serine/threonine-protein kinase ppk11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O46339	HTH_DROME	Homeobox protein homothorax	9346235	Nuclear translocation of extradenticle requires homothorax, which encodes an extradenticle-related homeodomain protein.

P38264	PHO88_YEAST	Inorganic phosphate transport protein PHO88	8709965	A putative membrane protein, Pho88p, involved in inorganic phosphate transport in Saccharomyces cerevisiae.

P30416	FKBP4_MOUSE	Peptidyl-prolyl cis-trans isomerase FKBP4	8341706	Overexpression, characterization, and purification of a recombinant mouse immunophilin FKBP-52 and identification of an associated phosphoprotein.

Q9W4S7	MYC_DROME	Myc protein	16087886	Myc interacts genetically with Tip48/Reptin and Tip49/Pontin to control growth and proliferation during Drosophila development.

P0A8A8	RIMP_ECOLI	Ribosome maturation factor rimP	19150615	The RimP protein is important for maturation of the 30S ribosomal subunit.

P29674	LHX1_XENLA	LIM/homeobox protein Lhx1	11291848	A study of Xlim1 function in the Spemann-Mangold organizer.

P51559	BLI4_CAEEL	Endoprotease bli-4	7774813	The bli-4 locus of Caenorhabditis elegans encodes structurally distinct kex2/subtilisin-like endoproteases essential for early development and adult morphology.

Q9JI57	GT2D1_MOUSE	General transcription factor II-I repeat domain-containing protein 1	10861001	Isolation and characterization of BEN, a member of the TFII-I family of DNA-binding proteins containing distinct helix-loop-helix domains.

Q8S3U9	EXOC2_ARATH	Exocyst complex component 2	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

O88382	MAGI2_RAT	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2	15951562	Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases.

O43236	SEPT4_HUMAN	Septin-4	9889007	Characterization of a novel gene, PNUTL2, on human chromosome 17q22- q23 and its exclusion as the Meckel syndrome gene.

P35563	5HT3A_RAT	5-hydroxytryptamine receptor 3A	10854267	Evidence for expression of heteromeric serotonin 5-HT(3) receptors in rodents.

Q9HBA0	TRPV4_HUMAN	Transient receptor potential cation channel subfamily V member 4	16293632	Human TRPV4 channel splice variants revealed a key role of ankyrin domains in multimerization and trafficking.

P52434	RPAB3_HUMAN	DNA-directed RNA polymerases I, II, and III subunit RPABC3	9852112	Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.

Q9UBC3	DNM3B_HUMAN	DNA (cytosine-5)-methyltransferase 3B	10433969	Cloning, expression and chromosome locations of the human DNMT3 gene family.

Q00453	RGM1_YEAST	Probable transcription repressor protein RGM1	1923755	The yeast putative transcriptional repressor RGM1 is a proline-rich zinc finger protein.

O60171	TAF10_SCHPO	Transcription initiation factor TFIID subunit 10	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9JKB1	UCHL3_MOUSE	Ubiquitin carboxyl-terminal hydrolase isozyme L3	19837878	Ubiquitin carboxyl-terminal hydrolase l3 promotes insulin signaling and adipogenesis.

Q9R006	PR7A2_RAT	Prolactin-7A2	10657001	Identification of two new nonclassical members of the rat prolactin family.

Q9Y2Y1	RPC10_HUMAN	DNA-directed RNA polymerase III subunit RPC10	9869639	The RNA cleavage activity of RNA polymerase III is mediated by an essential TFIIS-like subunit and is important for transcription termination.

P31209	PABP_SCHPO	Polyadenylate-binding protein, cytoplasmic and nuclear	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q62826	HNRPM_RAT	Heterogeneous nuclear ribonucleoprotein M	11406629	Heterogeneous RNA-binding protein M4 is a receptor for carcinoembryonic antigen in Kupffer cells.

P38345	FMP21_YEAST	Protein FMP21, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P83267	PRT32_HYDCO	Sperm protamine R3 isoform 2	8875866	The primary structure of a chondrichthyan protamine: a new apparent contradiction in protamine evolution.

P58801	RIPK2_MOUSE	Receptor-interacting serine/threonine-protein kinase 2	11894097	Involvement of receptor-interacting protein 2 in innate and adaptive immune responses.

O59703	GGPPS_SCHPO	Geranylgeranyl pyrophosphate synthase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q3E784	SLO1_YEAST	SCOCO-like protein 1	12620189	The ARF-like GTPases Arl1p and Arl3p act in a pathway that interacts with vesicle-tethering factors at the Golgi apparatus.

P83863	H2B_LITVA	Histone H2B	15606770	Antimicrobial activity of histones from hemocytes of the Pacific white shrimp.

Q7ZV84	LRC50_DANRE	Leucine-rich repeat-containing protein 50	18385425	LRRC50, a conserved ciliary protein implicated in polycystic kidney disease.

P25389	KCC4_YEAST	Probable serine/threonine-protein kinase KCC4	12773812	The Saccharomyces cerevisiae bud-neck proteins Kcc4 and Gin4 have distinct but partially-overlapping cellular functions.

Q9HD15	SRA1_HUMAN	Steroid receptor RNA activator 1	12565891	Identification of new human coding steroid receptor RNA activator isoforms.

Q02158	PLC_DICDI	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase	15075287	Identification of genes dependent on the MADS box transcription factor SrfA in Dictyostelium discoideum development.

Q90VV1	HES4B_XENLA	Transcription factor HES-4-B	17724611	Two alloalleles of Xenopus laevis hairy2 gene-evolution of duplicated gene function from a developmental perspective.

Q96RL7	VP13A_HUMAN	Vacuolar protein sorting-associated protein 13A	11381253	A conserved sorting-associated protein is mutant in chorea- acanthocytosis.

P84385	XT5_XENTR	Antimicrobial peptide 5	11738090	Antimicrobial peptides isolated from skin secretions of the diploid frog, Xenopus tropicalis (Pipidae).

P0C7L8	PPR3E_RAT	Protein phosphatase 1 regulatory subunit 3E	15752363	A novel glycogen-targeting subunit of protein phosphatase 1 that is regulated by insulin and shows differential tissue distribution in humans and rodents.

O20250	TKTC_SPIOL	Transketolase, chloroplastic	8980496	Molecular characterization of transketolase (EC 2.2.1.1) active in the Calvin cycle of spinach chloroplasts.

Q9XZ08	EXT3_DROME	Exostosin-3	11832488	Demonstration of a novel gene DEXT3 of Drosophila melanogaster as the essential N-acetylglucosamine transferase in the heparan sulfate biosynthesis: chain initiation and elongation.

Q9H4A3	WNK1_HUMAN	Serine/threonine-protein kinase WNK1	10660600	PSK, a novel STE20-like kinase derived from prostatic carcinoma that activates the JNK MAPK pathway and regulates actin cytoskeletal organisation.

Q8STF6	DYC1_CAEEL	Dystrophin-like protein 1	10996789	Genetic suppression of phenotypes arising from mutations in dystrophin-related genes in Caenorhabditis elegans.

Q08881	ITK_HUMAN	Tyrosine-protein kinase ITK/TSK	8364206	Identification, cloning, and characterization of a novel human T- cell-specific tyrosine kinase located at the hematopoietin complex on chromosome 5q.

O60260	PRKN2_HUMAN	E3 ubiquitin-protein ligase parkin	11590439	Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease.

Q06541	ARV1_YEAST	Protein ARV1	11063737	Mutations in yeast ARV1 alter intracellular sterol distribution and are complemented by human ARV1.

P51869	CP4F4_RAT	Cytochrome P450 4F4	11980497	Covalent attachment of the heme prosthetic group in the CYP4F cytochrome P450 family.

P70188	KIFA3_MOUSE	Kinesin-associated protein 3	8710890	Cloning and characterization of KAP3: a novel kinesin superfamily- associated protein of KIF3A/3B.

P34146	RAC1C_DICDI	Rho-related protein rac1C	15509655	Cellular distribution and functions of wild-type and constitutively activated Dictyostelium PakB.

Q811S9	GNL3_RAT	Guanine nucleotide-binding protein-like 3	12464630	A nucleolar mechanism controlling cell proliferation in stem and cancer cells.

P31386	ATS1_YEAST	Protein ATS1	8070652	Overexpression of yeast homologs of the mammalian checkpoint gene RCC1 suppresses the class of alpha-tubulin mutations that arrest with excess microtubules.

Q9LYN8	EXS_ARATH	Leucine-rich repeat receptor protein kinase EXS	12154130	The EXCESS MICROSPOROCYTES1 gene encodes a putative leucine-rich repeat receptor protein kinase that controls somatic and reproductive cell fates in the Arabidopsis anther.

O75444	MAF_HUMAN	Transcription factor Maf	9616139	Frequent dysregulation of the c-maf proto-oncogene at 16q23 by translocation to an Ig locus in multiple myeloma.

Q9UBN4	TRPC4_HUMAN	Short transient receptor potential channel 4	20164195	The phospholipid-binding protein SESTD1 is a novel regulator of the transient receptor potential channels TRPC4 and TRPC5.

Q62952	DPYL3_RAT	Dihydropyrimidinase-related protein 3	12684468	TUC-4b, a novel TUC family variant, regulates neurite outgrowth and associates with vesicles in the growth cone.

Q91V33	KHDR1_RAT	KH domain-containing, RNA-binding, signal transduction-associated protein 1	15345239	p59(fyn)-mediated phosphorylation regulates the activity of the tissue-specific splicing factor rSLM-1.

P00742	FA10_HUMAN	Coagulation factor X	3011603	Isolation and characterization of human blood-coagulation factor X cDNA.

Q55FP0	PHG1A_DICDI	Putative phagocytic receptor 1a	12857872	Synergistic control of cellular adhesion by transmembrane 9 proteins.

P0A998	FTNA_ECOLI	Ferritin-1	9720927	How the presence of three iron binding sites affects the iron storage function of the ferritin (EcFtnA) of Escherichia coli.

Q9CQF8	RT63_MOUSE	Ribosomal protein 63, mitochondrial	11402041	Proteomic analysis of the mammalian mitochondrial ribosome. Identification of protein components in the 28S small subunit.

Q9BQE9	BCL7B_HUMAN	B-cell CLL/lymphoma 7 protein family member B	8605326	Molecular cloning of complex chromosomal translocation t(8;14;12)(q24.1;q32.3;q24.1) in a Burkitt lymphoma cell line defines a new gene (BCL7A) with homology to caldesmon.

Q7Z2E3	APTX_HUMAN	Aprataxin	16547001	Aprataxin forms a discrete branch in the HIT (histidine triad) superfamily of proteins with both DNA/RNA binding and nucleotide hydrolase activities.

Q8BJ56	PLPL2_MOUSE	Patatin-like phospholipase domain-containing protein 2	17074755	Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism.

P13587	ATN1_YEAST	Sodium transport ATPase 1	7664728	The PMR2 gene cluster encodes functionally distinct isoforms of a putative Na+ pump in the yeast plasma membrane.

P38627	URA8_YEAST	CTP synthase 2	8121398	Use of synthetic lethal mutants to clone and characterize a novel CTP synthetase gene in Saccharomyces cerevisiae.

Q03957	CTK1_YEAST	CTD kinase subunit alpha	11118453	Activation of the cyclin-dependent kinase CTDK-I requires the heterodimerization of two unstable subunits.

Q94IA6	C90D1_ARATH	3-epi-6-deoxocathasterone 23-monooxygenase	17138693	C-23 hydroxylation by Arabidopsis CYP90C1 and CYP90D1 reveals a novel shortcut in brassinosteroid biosynthesis.

Q24395	MTK_DROME	Metchnikowin	7588819	Metchnikowin, a novel immune-inducible proline-rich peptide from Drosophila with antibacterial and antifungal properties.

P35968	VGFR2_HUMAN	Vascular endothelial growth factor receptor 2	1656371	Identification of a new endothelial cell growth factor receptor tyrosine kinase.

A2A935	PRD16_MOUSE	PR domain zinc finger protein 16	18719582	PRDM16 controls a brown fat/skeletal muscle switch.

P78381	S35A2_HUMAN	UDP-galactose translocator	9010752	Molecular cloning and characterization of a novel isoform of the human UDP-galactose transporter, and of related complementary DNAs belonging to the nucleotide-sugar transporter gene family.

Q9WTI7	MYO1C_MOUSE	Myosin-Ic	12490950	Glucose transporter recycling in response to insulin is facilitated by myosin Myo1c.

Q16630	CPSF6_HUMAN	Cleavage and polyadenylation specificity factor subunit 6	14690600	A mechanism for the regulation of pre-mRNA 3' processing by human cleavage factor Im.

Q9CZX5	PINX1_MOUSE	PIN2/TERF1-interacting telomerase inhibitor 1	11701125	The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor.

P84087	CPLX2_RAT	Complexin-2	7553862	Complexins: cytosolic proteins that regulate SNAP receptor function.

P22736	NR4A1_HUMAN	Nuclear receptor subfamily 4 group A member 1	2626032	Isolation and characterization of human TR3 receptor: a member of steroid receptor superfamily.

P69423	TATC_ECOLI	Sec-independent protein translocase protein tatC	9660752	An essential component of a novel bacterial protein export system with homologues in plastids and mitochondria.

P33891	TIP20_YEAST	Protein transport protein TIP20	16429126	Proteome survey reveals modularity of the yeast cell machinery.

Q9DG23	POPD1_CHICK	Blood vessel epicardial substance	16188940	Bves modulates epithelial integrity through an interaction at the tight junction.

P22803	TRX2_YEAST	Thioredoxin-2	2026619	Thioredoxin deficiency in yeast prolongs S phase and shortens the G1 interval of the cell cycle.

Q9UP38	FZD1_HUMAN	Frizzled-1	10557084	Human frizzled 1 interacts with transforming Wnts to transduce a TCF dependent transcriptional response.

Q9JL21	CCR10_MOUSE	C-C chemokine receptor type 10	10781587	Identification of a novel chemokine (CCL28), which binds CCR10 (GPR2).

Q307W7	KNCN_MOUSE	Kinocilin	15855039	Initial characterization of kinocilin, a protein of the hair cell kinocilium.

P53840	TOF1_YEAST	Topoisomerase 1-associated factor 1	16418273	The Tof1p-Csm3p protein complex counteracts the Rrm3p helicase to control replication termination of Saccharomyces cerevisiae.

P0C191	GPVI_MOUSE	Platelet glycoprotein VI	10961879	Cloning, characterization, and functional studies of human and mouse glycoprotein VI: a platelet-specific collagen receptor from the immunoglobulin superfamily.

Q08245	ZEO1_YEAST	Protein ZEO1	12949174	A synthetic analysis of the Saccharomyces cerevisiae stress sensor Mid2p, and identification of a Mid2p-interacting protein, Zeo1p, that modulates the PKC1-MPK1 cell integrity pathway.

Q9H0H5	RGAP1_HUMAN	Rac GTPase-activating protein 1	11085985	MgcRacGAP is involved in cytokinesis through associating with mitotic spindle and midbody.

Q8K2X3	STN1_MOUSE	CST complex subunit STN1	19854130	RPA-like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathway.

O74544	GTR2_SCHPO	GTP-binding protein gtr2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O35274	NEB2_RAT	Neurabin-2	10391935	Association of the D2 dopamine receptor third cytoplasmic loop with spinophilin, a protein phosphatase-1-interacting protein.

Q96524	CRY2_ARATH	Cryptochrome-2	9565033	Cryptochrome blue-light photoreceptors of Arabidopsis implicated in phototropism.

Q92729	PTPRU_HUMAN	Receptor-type tyrosine-protein phosphatase U	16574648	Protein-tyrosine phosphatase PCP-2 inhibits beta-catenin signaling and increases E-cadherin-dependent cell adhesion.

P11177	ODPB_HUMAN	Pyruvate dehydrogenase E1 component subunit beta, mitochondrial	2376596	Characterization of two cDNA clones for pyruvate dehydrogenase E1 beta subunit and its regulation in tricarboxylic acid cycle-deficient fibroblast.

O88778	BSN_RAT	Protein bassoon	9679147	Bassoon, a novel zinc-finger CAG/Glutamine-repeat protein selectively localized at the active zone of presynaptic nerve terminals.

P47224	MSS4_HUMAN	Guanine nucleotide exchange factor MSS4	7619808	Cloning, Zn2+ binding, and structural characterization of the guanine nucleotide exchange factor human Mss4.

P38255	RXT2_YEAST	Transcriptional regulatory protein RXT2	16314178	Stable incorporation of sequence specific repressors Ash1 and Ume6 into the Rpd3L complex.

P70483	STRN_RAT	Striatin	8769426	A novel calmodulin-binding protein, belonging to the WD-repeat family, is localized in dendrites of a subset of CNS neurons.

Q9BU02	THTPA_HUMAN	Thiamine-triphosphatase	11827967	Molecular characterization of a specific thiamine triphosphatase widely expressed in mammalian tissues.

P33420	NIP80_YEAST	Protein NIP100	9658168	The yeast dynactin complex is involved in partitioning the mitotic spindle between mother and daughter cells during anaphase B.

B7ZR65	SOX9A_XENLA	Transcription factor Sox-9-A	12812785	Sox10 regulates the development of neural crest-derived melanocytes in Xenopus.

Q9NP60	IRPL2_HUMAN	X-linked interleukin-1 receptor accessory protein-like 2	10757639	Two novel members of the interleukin-1 receptor gene family, one deleted in Xp22.3-Xp21.3 mental retardation.

Q12325	SUL2_YEAST	Sulfate permease 2	9055073	Molecular characterization of two high affinity sulfate transporters in Saccharomyces cerevisiae.

Q13426	XRCC4_HUMAN	DNA repair protein XRCC4	17396150	A novel human AP endonuclease with conserved zinc-finger-like motifs involved in DNA strand break responses.

Q9JMB7	PIWL1_MOUSE	Piwi-like protein 1	12062093	miwi, a murine homolog of piwi, encodes a cytoplasmic protein essential for spermatogenesis.

Q9URZ3	PUT4_SCHPO	Probable proline-specific permease put4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8IWI9	MGAP_HUMAN	MAX gene-associated protein	15960975	Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

Q01650	LAT1_HUMAN	Large neutral amino acids transporter small subunit 1	9751058	Amino-acid transport by heterodimers of 4F2hc/CD98 and members of a permease family.

Q92692	PVRL2_HUMAN	Poliovirus receptor-related protein 2	19011627	The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.

P53141	MLC1_YEAST	Myosin light chain 1	9700160	Mlc1p is a light chain for the unconventional myosin Myo2p in Saccharomyces cerevisiae.

Q9Y282	ERGI3_HUMAN	Endoplasmic reticulum-Golgi intermediate compartment protein 3	15308636	Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46.

Q3U827	RN180_MOUSE	E3 ubiquitin-protein ligase RNF180	18363970	Rines/RNF180, a novel RING finger gene-encoded product, is a membrane-bound ubiquitin ligase.

P25694	CDC48_YEAST	Cell division control protein 48	1860879	Yeast cell cycle protein CDC48p shows full-length homology to the mammalian protein VCP and is a member of a protein family involved in secretion, peroxisome formation, and gene expression.

Q8L7V3	PMTQ_ARATH	Probable methyltransferase PMT26	16618929	Mapping the Arabidopsis organelle proteome.

P12830	CADH1_HUMAN	Cadherin-1	12526809	Structure of internalin, a major invasion protein of Listeria monocytogenes, in complex with its human receptor E-cadherin.

O43463	SUV91_HUMAN	Histone-lysine N-methyltransferase SUV39H1	11242053	Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins.

P40086	COX15_YEAST	Cytochrome c oxidase assembly protein COX15	9228094	COX15 codes for a mitochondrial protein essential for the assembly of yeast cytochrome oxidase.

P50942	INP52_YEAST	Inositol-1,4,5-trisphosphate 5-phosphatase 2	10224048	SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatases.

Q9Y6H5	SNCAP_HUMAN	Synphilin-1	10319874	Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions.

Q9P7X2	ELL1_SCHPO	RNA polymerase II elongation factor ell1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P0CC11	BENG_HETBN	Bengalin	19913524	Apoptosis induction in human leukemic cells by a novel protein Bengalin, isolated from Indian black scorpion venom: through mitochondrial pathway and inhibition of heat shock proteins.

Q61955	KLK8_MOUSE	Kallikrein-8	17629414	Neuropsin promotes oligodendrocyte death, demyelination and axonal degeneration after spinal cord injury.

P19447	ERCC3_HUMAN	TFIIH basal transcription factor complex helicase XPB subunit	2167179	A presumed DNA helicase encoded by ERCC-3 is involved in the human repair disorders Xeroderma pigmentosum and Cockayne's syndrome.

P68032	ACTC_HUMAN	Actin, alpha cardiac muscle 1	9563954	Actin mutations in dilated cardiomyopathy, a heritable form of heart failure.

Q92207	HOG1_CANAL	Mitogen-activated protein kinase HOG1	16339080	Role of the Hog1 stress-activated protein kinase in the global transcriptional response to stress in the fungal pathogen Candida albicans.

P50107	LGUL_YEAST	Lactoylglutathione lyase	8824231	Identification of the structural gene for glyoxalase I from Saccharomyces cerevisiae.

Q7LKZ6	YJMD_SCHPO	Probable phospholipase C1020.13c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P45953	ACADV_RAT	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	8034667	Rat very-long-chain acyl-CoA dehydrogenase, a novel mitochondrial acyl-CoA dehydrogenase gene product, is a rate-limiting enzyme in long-chain fatty acid beta-oxidation system. cDNA and deduced amino acid sequence and distinct specificities of the cDNA-expressed protein.

P19652	A1AG2_HUMAN	Alpha-1-acid glycoprotein 2	2970990	Structure and characterisation of a duplicated human alpha 1 acid glycoprotein gene.

Q8VHX2	EDAD_MOUSE	Ectodysplasin-A receptor-associated adapter protein	11882293	Identification of a novel DEATH domain-containing adaptor molecule for ectodysplasin-A receptor that is mutated in crinkled mice.

Q8IU60	DCP2_HUMAN	mRNA-decapping enzyme 2	16364915	Multiple processing body factors and the ARE binding protein TTP activate mRNA decapping.

Q7YS70	MECR_BOVIN	Trans-2-enoyl-CoA reductase, mitochondrial	12654921	Characterization of 2-enoyl thioester reductase from mammals: an ortholog of Ybr026p/Mrf1'p of the yeast mitochondrial fatty acid synthesis type II.

P06780	RHO1_YEAST	GTP-binding protein RHO1	9242378	Association of the Rho family small GTP-binding proteins with Rho GDP dissociation inhibitor (Rho GDI) in Saccharomyces cerevisiae.

Q15365	PCBP1_HUMAN	Poly(rC)-binding protein 1	7607214	Characterisation of two major cellular poly(rC)-binding human proteins, each containing three K-homologous (KH) domains.

P38869	SVP26_YEAST	Protein SVP26	14562095	Global analysis of protein localization in budding yeast.

P43579	IES1_YEAST	Ino eighty subunit 1	12887900	Involvement of actin-related proteins in ATP-dependent chromatin remodeling.

Q8N3Y7	RDHE2_HUMAN	Epidermal retinol dehydrogenase 2	12372410	Identification of the hRDH-E2 gene, a novel member of the SDR family, and its increased expression in psoriatic lesion.

Q16851	UGPA_HUMAN	UTP--glucose-1-phosphate uridylyltransferase	8631325	Sequence differences between human muscle and liver cDNAs for UDPglucose pyrophosphorylase and kinetic properties of the recombinant enzymes expressed in Escherichia coli.

P39012	GAA1_YEAST	GPI transamidase component GAA1	11598210	The GPI transamidase complex of Saccharomyces cerevisiae contains Gaa1p, Gpi8p, and Gpi16p.

Q42592	APXS_ARATH	L-ascorbate peroxidase S, chloroplastic/mitochondrial	12954611	Molecular definition of the ascorbate-glutathione cycle in Arabidopsis mitochondria reveals dual targeting of antioxidant defenses in plants.

P23490	LORI_HUMAN	Loricrin	2007607	Characterization of human loricrin. Structure and function of a new class of epidermal cell envelope proteins.

P12956	XRCC6_HUMAN	X-ray repair cross-complementing protein 6	2917966	Cloning and characterization of a cDNA that encodes a 70-kDa novel human thyroid autoantigen.

Q7JXV9	VPS25_DROME	Vacuolar protein-sorting-associated protein 25	19132102	Common and distinct genetic properties of ESCRT-II components in Drosophila.

P35734	ASK1_YEAST	DASH complex subunit ASK1	15640796	The yeast DASH complex forms closed rings on microtubules.

Q07666	KHDR1_HUMAN	KH domain-containing, RNA-binding, signal transduction-associated protein 1	9013542	A role for Sam68 in cell cycle progression antagonized by a spliced variant within the KH domain.

Q96RI1	NR1H4_HUMAN	Bile acid receptor	12815072	Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis.

O00238	BMR1B_HUMAN	Bone morphogenetic protein receptor type-1B	14523231	Mutations in bone morphogenetic protein receptor 1B cause brachydactyly type A2.

Q99571	P2RX4_HUMAN	P2X purinoceptor 4	9016352	Characterization of recombinant human P2X4 receptor reveals pharmacological differences to the rat homologue.

P18487	A37C_DROME	Protein anon-37Cs	2874495	Overlapping transcription units in the dopa decarboxylase region of Drosophila.

Q9ESC2	TNMD_RAT	Tenomodulin	11162640	Molecular cloning and characterization of ChM1L, a novel membrane molecule similar to chondromodulin-I.

P70486	ATRX_RAT	Transcriptional regulator ATRX	8667030	Molecular cloning and characterization of annexin V-binding proteins with highly hydrophilic peptide structure.

Q3T0X9	DPOD4_BOVIN	DNA polymerase delta subunit 4	10751307	Identification of a fourth subunit of mammalian DNA polymerase delta.

Q63618	ESPN_RAT	Espin	9763424	Small espin: a third actin-bundling protein and potential forked protein ortholog in brush border microvilli.

P40479	SDP1_YEAST	Dual-specificity protein phosphatase SDP1	17495930	Redox-mediated substrate recognition by Sdp1 defines a new group of tyrosine phosphatases.

Q8MLZ5	GAP2_CAEEL	Ras GTPase-activating protein gap-2	9619631	Characterization of the C. elegans gap-2 gene encoding a novel Ras- GTPase activating protein and its possible role in larval development.

P0AC84	GLO2_ECOLI	Hydroxyacylglutathione hydrolase	17196158	Escherichia coli glyoxalase II is a binuclear zinc-dependent metalloenzyme.

Q13114	TRAF3_HUMAN	TNF receptor-associated factor 3	9162022	Herpesvirus entry mediator, a member of the tumor necrosis factor receptor (TNFR) family, interacts with members of the TNFR-associated factor family and activates the transcription factors NF-kappaB and AP-1.

P47884	OR1D4_HUMAN	Olfactory receptor 1D4	8004088	Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire.

P53598	SUCA_YEAST	Succinyl-CoA ligase [ADP-forming] subunit alpha, mitochondrial	9874242	Genes of succinyl-CoA ligase from Saccharomyces cerevisiae.

Q52KG5	KI26A_MOUSE	Kinesin-like protein KIF26A	19914172	KIF26A is an unconventional kinesin and regulates GDNF-Ret signaling in enteric neuronal development.

Q09014	NCF1_MOUSE	Neutrophil cytosol factor 1	8119734	Cloning and functional expression of the mouse homologue of p47phox.

P54861	DNM1_YEAST	Dynamin-related protein DNM1	10559943	The dynamin-related GTPase Dnm1 regulates mitochondrial fission in yeast.

P51683	CCR2_MOUSE	C-C chemokine receptor type 2	8662823	Cloning and functional expression of mCCR2, a murine receptor for the C-C chemokines JE and FIC.

Q9EQU3	TLR9_MOUSE	Toll-like receptor 9	11130078	A Toll-like receptor recognizes bacterial DNA.

O95630	STABP_HUMAN	STAM-binding protein	14755250	An RNF11: Smurf2 complex mediates ubiquitination of the AMSH protein.

P34482	ZIF1_CAEEL	Zinc finger-interacting factor 1	12894212	Exclusion of germ plasm proteins from somatic lineages by cullin- dependent degradation.

Q9NPE6	SPAG4_HUMAN	Sperm-associated antigen 4 protein	9691178	A novel testis-specific gene, SPAG4, whose product interacts specifically with outer dense fiber protein ODF27, maps to human chromosome 20q11.2.

P53721	AIM38_YEAST	Altered inheritance rate of mitochondria protein 38	14562095	Global analysis of protein localization in budding yeast.

P84022	SMAD3_HUMAN	Mothers against decapentaplegic homolog 3	14525983	DACH1 inhibits transforming growth factor-beta signaling through binding Smad4.

Q03785	VHS1_YEAST	Serine/threonine-protein kinase VHS1	12518319	Identification of multicopy suppressors of cell cycle arrest at the G1-S transition in Saccharomyces cerevisiae.

P42641	OBG_ECOLI	GTPase ObgE/CgtA	15292126	The Escherichia coli GTPase CgtAE cofractionates with the 50S ribosomal subunit and interacts with SpoT, a ppGpp synthetase/hydrolase.

O00487	PSDE_HUMAN	26S proteasome non-ATPase regulatory subunit 14	9374539	Resistance to diverse drugs and ultraviolet light conferred by overexpression of a novel human 26 S proteasome subunit.

Q9UUB7	SWI5_SCHPO	Mating-type switching protein swi5	14663140	Two different Swi5-containing protein complexes are involved in mating-type switching and recombination repair in fission yeast.

P30411	BKRB2_HUMAN	B2 bradykinin receptor	7916737	Human bradykinin B2 receptor: nucleotide sequence analysis and assignment to chromosome 14.

P53064	RTF1_YEAST	RNA polymerase-associated protein RTF1	15643076	Separation of the Saccharomyces cerevisiae Paf1 complex from RNA polymerase II results in changes in its subnuclear localization.

Q01301	CCG4_NEUCR	Clock-controlled pheromone ccg-4	12139624	The Neurospora crassa pheromone precursor genes are regulated by the mating type locus and the circadian clock.

Q8TDN4	CABL1_HUMAN	CDK5 and ABL1 enzyme substrate 1	11706030	Differential effect of ik3-1/cables on p53- and p73-induced cell death.

P55008	AIF1_HUMAN	Allograft inflammatory factor 1	18699778	Structural and functional characterization of human Iba proteins.

Q9VZ23	RAN_DROME	GTP-binding nuclear protein Ran	12653959	Tamo selectively modulates nuclear import in Drosophila.

P41145	OPRK_HUMAN	Kappa-type opioid receptor	7624359	Kappa-opioid receptor in humans: cDNA and genomic cloning, chromosomal assignment, functional expression, pharmacology, and expression pattern in the central nervous system.

Q9UBN7	HDAC6_HUMAN	Histone deacetylase 6	10220385	Three proteins define a class of human histone deacetylases related to yeast Hda1p.

Q5TEJ8	THMS2_HUMAN	Protein THEMIS2	9563507	A novel basement membrane-induced gene identified in the human endometrial adenocarcinoma cell line HEC1B.

O75030	MITF_HUMAN	Microphthalmia-associated transcription factor	10578055	Molecular cloning of cDNA encoding a novel microphthalmia-associated transcription factor isoform with a distinct amino-terminus.

O15270	SPTC2_HUMAN	Serine palmitoyltransferase 2	19416851	Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities.

P62269	RS18_HUMAN	40S ribosomal protein S18	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

Q06412	TUS1_YEAST	Rho1 guanine nucleotide exchange factor TUS1	11839800	Yeast protein kinases and the RHO1 exchange factor TUS1 are novel components of the cell integrity pathway in yeast.

Q04712	RRN11_YEAST	RNA polymerase I-specific transcription initiation factor RRN11	8887672	A novel 66-kilodalton protein complexes with Rrn6, Rrn7, and TATA- binding protein to promote polymerase I transcription initiation in Saccharomyces cerevisiae.

Q94517	HDAC1_DROME	Histone deacetylase Rpd3	12408863	Drosophila Enhancer of zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites.

O13968	YE48_SCHPO	Uncharacterized carboxypeptidase C24C9.08	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UHI5	LAT2_HUMAN	Large neutral amino acids transporter small subunit 2	11311135	Association of 4F2hc with light chains LAT1, LAT2 or y+LAT2 requires different domains.

Q99683	M3K5_HUMAN	Mitogen-activated protein kinase kinase kinase 5	8974401	Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways.

P38344	REI1_YEAST	Pre-60S factor REI1	15107529	Ybr267w is a new cytoplasmic protein belonging to the mitotic signaling network of Saccharomyces cerevisiae.

Q02790	FKBP4_HUMAN	Peptidyl-prolyl cis-trans isomerase FKBP4	2378870	The 56-59-kilodalton protein identified in untransformed steroid receptor complexes is a unique protein that exists in cytosol in a complex with both the 70- and 90-kilodalton heat shock proteins.

Q06055	AT5G2_HUMAN	ATP synthase lipid-binding protein, mitochondrial	8328972	Sequences of members of the human gene family for the c subunit of mitochondrial ATP synthase.

Q92754	AP2C_HUMAN	Transcription factor AP-2 gamma	9113991	Identification of ERF-1 as a member of the AP2 transcription factor family.

P05186	PPBT_HUMAN	Alkaline phosphatase, tissue-nonspecific isozyme	9781036	Identification of fifteen novel mutations in the tissue-nonspecific alkaline phosphatase (TNSALP) gene in European patients with severe hypophosphatasia.

Q9HDU9	YHE6_SCHPO	Uncharacterized protein PB2B2.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9BX63	FANCJ_HUMAN	Fanconi anemia group J protein	11301010	BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function.

P16638	ACLY_RAT	ATP-citrate synthase	2295639	Rat ATP citrate-lyase. Molecular cloning and sequence analysis of a full-length cDNA and mRNA abundance as a function of diet, organ, and age.

O74462	TAF6_SCHPO	Transcription initiation factor TFIID subunit 6	11972332	Identification of histone H4-like TAF in Schizosaccharomyces pombe as a protein that interacts with WD repeat-containing TAF.

Q9NBD7	CLASP_DROME	CLIP-associating protein	15207236	The microtubule plus end tracking protein Orbit/MAST/CLASP acts downstream of the tyrosine kinase Abl in mediating axon guidance.

Q6UWZ7	F175A_HUMAN	BRCA1-A complex subunit Abraxas	19261749	NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control.

P36088	FRMSR_YEAST	Free methionine-R-sulfoxide reductase	14562095	Global analysis of protein localization in budding yeast.

Q8R400	ADIG_MOUSE	Adipogenin	15567149	Cloning, expression, and differentiation-dependent regulation of SMAF1 in adipogenesis.

P04757	ACHA3_RAT	Neuronal acetylcholine receptor subunit alpha-3	2444984	Functional expression of two neuronal nicotinic acetylcholine receptors from cDNA clones identifies a gene family.

P38646	GRP75_HUMAN	Stress-70 protein, mitochondrial	7684501	Cloning of the gene encoding peptide-binding protein 74 shows that it is a new member of the heat shock protein 70 family.

P14174	MIF_HUMAN	Macrophage migration inhibitory factor	12681488	The apoptosis-associated protein BNIPL interacts with two cell proliferation-related proteins, MIF and GFER.

Q42546	DPNP1_ARATH	SAL1 phosphatase	8721754	The SAL1 gene of Arabidopsis, encoding an enzyme with 3'(2'),5'- bisphosphate nucleotidase and inositol polyphosphate 1-phosphatase activities, increases salt tolerance in yeast.

O95665	NTR2_HUMAN	Neurotensin receptor type 2	9851594	Neurotensin is an antagonist of the human neurotensin NT2 receptor expressed in Chinese hamster ovary cells.

P78560	CRADD_HUMAN	Death domain-containing protein CRADD	9044836	CRADD, a novel human apoptotic adaptor molecule for caspase-2, and FasL/tumor necrosis factor receptor-interacting protein RIP.

P01733	TVB1_HUMAN	T-cell receptor beta chain V region YT35	6336315	A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains.

Q9Y5P8	P2R3B_HUMAN	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta	10629059	PR48, a novel regulatory subunit of protein phosphatase 2A, interacts with cdc6 and modulates DNA replication in human cells.

O84947	SSEC_SALTY	Secreted effector protein sseC	11159962	Salmonella pathogenicity island 2-encoded proteins SseC and SseD are essential for virulence and are substrates of the type III secretion system.

Q12468	CSN5_YEAST	COP9 signalosome complex subunit 5	12446563	COP9 signalosome components play a role in the mating pheromone response of S. cerevisiae.

P02780	SG2A2_RAT	Secretoglobin family 2A member 2	6294095	Prostatic steroid-binding protein. Isolation and characterization of C3 genes.

Q94BT6	ADO1_ARATH	Adagio protein 1	10847686	ZEITLUPE encodes a novel clock-associated PAS protein from Arabidopsis.

Q15070	OXA1L_HUMAN	Mitochondrial inner membrane protein OXA1L	7991568	Cloning of a human gene involved in cytochrome oxidase assembly by functional complementation of an oxa1- mutation in Saccharomyces cerevisiae.

P17883	SKI3_YEAST	Superkiller protein 3	9482746	The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex.

Q86B87	MMD4_DROME	Modifier of mdg4	8248257	The enhancer of position-effect variegation of Drosophila, E(var)3- 93D, codes for a chromatin protein containing a conserved domain common to several transcriptional regulators.

Q9QXP0	RHCG_MOUSE	Ammonium transporter Rh type C	10852913	Characterization of human RhCG and mouse Rhcg as novel nonerythroid Rh glycoprotein homologues predominantly expressed in kidney and testis.

Q9DCP9	DAZP2_MOUSE	DAZ-associated protein 2	14530442	Sox6 regulation of cardiac myocyte development.

P07251	ATPA_YEAST	ATP synthase subunit alpha, mitochondrial	11502169	Yeast mitochondrial dehydrogenases are associated in a supramolecular complex.

O00506	STK25_HUMAN	Serine/threonine-protein kinase 25	8887545	Activation of a human Ste20-like kinase by oxidant stress defines a novel stress response pathway.

Q06408	ARO10_YEAST	Transaminated amino acid decarboxylase	10753893	An investigation of the metabolism of isoleucine to active Amyl alcohol in Saccharomyces cerevisiae.

P13796	PLSL_HUMAN	Plastin-2	2378651	Correction of the N-terminal sequences of the human plastin isoforms by using anchored polymerase chain reaction: identification of a potential calcium-binding domain.

Q9NEW6	RSP3_CAEEL	Probable splicing factor, arginine/serine-rich 3	10747030	Functional characterization of SR and SR-related genes in Caenorhabditis elegans.

P47825	TAF4_DROME	Transcription initiation factor TFIID subunit 4	8327460	The Drosophila 110-kDa transcription factor TFIID subunit directly interacts with the N-terminal region of the 230-kDa subunit.

Q92889	XPF_HUMAN	DNA repair endonuclease XPF	19596235	Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair.

Q9GZZ8	LACRT_HUMAN	Extracellular glycoprotein lacritin	11419941	cDNA and genomic cloning of lacritin, a novel secretion enhancing factor from the human lacrimal gland.

Q8NE79	POPD1_HUMAN	Blood vessel epicardial substance	16188940	Bves modulates epithelial integrity through an interaction at the tight junction.

P32027	CROC_DROME	Fork head domain-containing protein crocodile	7489720	The Drosophila fork head domain protein crocodile is required for the establishment of head structures.

Q12946	FOXF1_HUMAN	Forkhead box protein F1	8626802	Differential activation of lung-specific genes by two forkhead proteins, FREAC-1 and FREAC-2.

Q03555	GEPH_RAT	Gephyrin	1319186	Primary structure and alternative splice variants of gephyrin, a putative glycine receptor-tubulin linker protein.

Q9Y7J9	MCP5_SCHPO	Meiotic coiled-coil protein 5	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

Q80X73	PELO_MOUSE	Protein pelota homolog	12556505	Disruption of the pelota gene causes early embryonic lethality and defects in cell cycle progression.

Q9C0Y6	YKM8_SCHPO	Zinc-type alcohol dehydrogenase-like protein PB24D3.08c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P0ACN4	ALLR_ECOLI	HTH-type transcriptional repressor AllR	16546208	Structural and biochemical study of effector molecule recognition by the E.coli glyoxylate and allantoin utilization regulatory protein AllR.

Q60996	2A5G_MOUSE	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform	8617797	Identification of a novel protein phosphatase 2A regulatory subunit highly expressed in muscle.

P57750	AGM1_ARATH	Phosphoacetylglucosamine mutase	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

Q9LQ10	1A110_ARATH	Probable aminotransferase ACS10	12968022	Biochemical diversity among the 1-amino-cyclopropane-1-carboxylate synthase isozymes encoded by the Arabidopsis gene family.

O13959	RBX1_SCHPO	RING-box protein pip1	12167173	Combinatorial diversity of fission yeast SCF ubiquitin ligases by homo- and heterooligomeric assemblies of the F-box proteins Pop1p and Pop2p.

Q70M86	STRN_SORMA	Striatin Pro11	14871953	A WD40 repeat protein regulates fungal cell differentiation and can be replaced functionally by the mammalian homologue striatin.

Q9P0X4	CAC1I_HUMAN	Voltage-dependent T-type calcium channel subunit alpha-1I	10454147	Structure and alternative splicing of the gene encoding alpha1I, a human brain T calcium channel alpha1 subunit.

Q9UDY8	MALT1_HUMAN	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	16123224	MALT1 contains nuclear export signals and regulates cytoplasmic localization of BCL10.

Q01959	SC6A3_HUMAN	Sodium-dependent dopamine transporter	10889531	Human dopamine transporter gene: coding region conservation among normal, Tourette's disorder, alcohol dependence and attention-deficit hyperactivity disorder populations.

Q9NQW8	CNGB3_HUMAN	Cyclic nucleotide-gated cation channel beta-3	10888875	Genetic basis of total colourblindness among the Pingelapese islanders.

P04774	SCN1A_RAT	Sodium channel protein type 1 subunit alpha	3754035	Existence of distinct sodium channel messenger RNAs in rat brain.

Q00013	EM55_HUMAN	55 kDa erythrocyte membrane protein	19144871	Identification of erythrocyte p55/MPP1 as a binding partner of NF2 tumor suppressor protein/Merlin.

P62483	KCAB2_RAT	Voltage-gated potassium channel subunit beta-2	10884227	Structure of the cytoplasmic beta subunit-T1 assembly of voltage- dependent K+ channels.

Q54D84	TRIA_DICDI	Trishanku	17177856	Trishanku, a novel regulator of cell-type stability and morphogenesis in Dictyostelium discoideum.

Q9NNW7	TRXR2_HUMAN	Thioredoxin reductase 2, mitochondrial	9923614	Cloning, sequencing and functional expression of a novel human thioredoxin reductase.

P40096	NCB1_YEAST	Negative cofactor 2 complex subunit alpha	9096360	Functional antagonism between RNA polymerase II holoenzyme and global negative regulator NC2 in vivo.

P61964	WDR5_HUMAN	WD repeat-containing protein 5	12670868	Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell- proliferation factor HCF-1.

P46309	GSH1_ARATH	Glutamate--cysteine ligase, chloroplastic	9807829	The glutathione-deficient, cadmium-sensitive mutant, cad2-1, of Arabidopsis thaliana is deficient in gamma-glutamylcysteine synthetase.

O74407	SYDC_SCHPO	Aspartyl-tRNA synthetase, cytoplasmic	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P32561	RPD3_YEAST	Histone deacetylase RPD3	14737171	The MAPK Hog1 recruits Rpd3 histone deacetylase to activate osmoresponsive genes.

Q03020	ISU1_YEAST	Iron sulfur cluster assembly protein 1, mitochondrial	10588895	Saccharomyces cerevisiae ISU1 and ISU2: members of a well-conserved gene family for iron-sulfur cluster assembly.

Q9ZWM9	RAV1_ARATH	AP2/ERF and B3 domain-containing transcription factor RAV1	15040885	Arabidopsis RAV1 is down-regulated by brassinosteroid and may act as a negative regulator during plant development.

P55197	AF10_HUMAN	Protein AF-10	7888665	A novel class of zinc finger/leucine zipper genes identified from the molecular cloning of the t(10;11) translocation in acute leukemia.

Q9NFU0	FMR1_DROME	Fragile X mental retardation syndrome-related protein 1	12818175	CYFIP/Sra-1 controls neuronal connectivity in Drosophila and links the Rac1 GTPase pathway to the fragile X protein.

Q66IG8	FXJ12_XENTR	Forkhead box protein J1.2	16461016	Developmental expression of FoxJ1.2, FoxJ2, and FoxQ1 in Xenopus tropicalis.

P22194	SDS22_SCHPO	Protein phosphatase 1 regulatory subunit SDS22	1846086	S. pombe gene sds22+ essential for a midmitotic transition encodes a leucine-rich repeat protein that positively modulates protein phosphatase-1.

P19484	TFEB_HUMAN	Transcription factor EB	2115126	A helix-loop-helix protein related to the immunoglobulin E box- binding proteins.

P16446	PIPNA_RAT	Phosphatidylinositol transfer protein alpha isoform	11104777	Structure of a multifunctional protein. Mammalian phosphatidylinositol transfer protein complexed with phosphatidylcholine.

Q9Y825	YEC6_SCHPO	Uncharacterized WD repeat-containing protein C25H1.06	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9USL6	YJK5_SCHPO	Putative hydroxymethylpyrimidine/phosphomethylpyrimidine kinase C18B5.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P0AED7	DAPE_ECOLI	Succinyl-diaminopimelate desuccinylase	1644752	Cloning, characterization, and expression of the dapE gene of Escherichia coli.

P36776	LONM_HUMAN	Lon protease homolog, mitochondrial	14739292	DNA and RNA binding by the mitochondrial lon protease is regulated by nucleotide and protein substrate.

A1L1I3	NUMBL_RAT	Numb-like protein	18299187	NUMBL interacts with TAB2 and inhibits TNFalpha and IL-1beta-induced NF-kappaB activation.

P14003	HAIR_DROME	Protein hairy	8649374	The WRPW motif of the hairy-related basic helix-loop-helix repressor proteins acts as a 4-amino-acid transcription repression and protein- protein interaction domain.

Q9JKU0	T2R16_RAT	Taste receptor type 2 member 16	10761934	A novel family of mammalian taste receptors.

Q8CIZ5	DMBT1_RAT	Deleted in malignant brain tumors 1 protein	12368192	Heterogeneity of ductular reactions in adult rat and human liver revealed by novel expression of deleted in malignant brain tumor 1.

Q9LES3	AI5L2_ARATH	ABSCISIC ACID-INSENSITIVE 5-like protein 2	11005831	Arabidopsis basic leucine zipper transcription factors involved in an abscisic acid-dependent signal transduction pathway under drought and high-salinity conditions.

P83120	MTH_DROSI	G-protein coupled receptor Mth	10995474	Adaptive evolution of a candidate gene for aging in Drosophila.

P18405	S5A1_HUMAN	3-oxo-5-alpha-steroid 4-dehydrogenase 1	1686016	Characterization and chromosomal mapping of a human steroid 5 alpha- reductase gene and pseudogene and mapping of the mouse homologue.

Q64289	NDF1_RAT	Neurogenic differentiation factor 1	10101232	Overexpression of NeuroD in PC12 cells alters morphology and enhances expression of the adenylate kinase isozyme 1 gene.

Q99MJ6	NHRF4_MOUSE	Na(+)/H(+) exchange regulatory cofactor NHE-RF4	19088451	Elevated intracellular calcium stimulates NHE3 activity by an IKEPP (NHERF4) dependent mechanism.

P61289	PSME3_HUMAN	Proteasome activator complex subunit 3	18309296	Proteasome activator PA28 gamma regulates p53 by enhancing its MDM2- mediated degradation.

Q9P7N2	AP1S1_SCHPO	AP-1 complex subunit sigma-1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q08300	YO159_YEAST	Uncharacterized protein YOL159C	11935221	Sequence-based approach for identification of cell wall proteins in Saccharomyces cerevisiae.

P33418	XPOT_YEAST	Exportin-T	9802895	tRNA nuclear export in saccharomyces cerevisiae: in situ hybridization analysis.

Q22292	TBX8_CAEEL	T-box transcription factor tbx-8	15066124	Caenorhabditis elegans T-box genes tbx-9 and tbx-8 are required for formation of hypodermis and body-wall muscle in embryogenesis.

O08586	PTEN_MOUSE	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	19778506	DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212.

P45463	TTDR_ECOLI	HTH-type transcriptional activator ttdR	16804186	Functional identification of ygiP as a positive regulator of the ttdA-ttdB-ygjE operon.

Q9C932	NAC19_ARATH	NAC domain-containing protein 19	15319476	Isolation and functional analysis of Arabidopsis stress-inducible NAC transcription factors that bind to a drought-responsive cis-element in the early responsive to dehydration stress 1 promoter.

A1Z8N1	TRE11_DROME	Facilitated trehalose transporter Tret1-1	20035867	The trehalose transporter 1 gene sequence is conserved in insects and encodes proteins with different kinetic properties involved in trehalose import into peripheral tissues.

P07323	ENOG_RAT	Gamma-enolase	2865729	Molecular cloning and the nucleotide sequence of cDNA for neuron- specific enolase messenger RNA of rat brain.

P04278	SHBG_HUMAN	Sex hormone-binding globulin	2587256	Characterization of the human sex hormone binding globulin (SHBG) gene and demonstration of two transcripts in both liver and testis.

Q9Y5F0	PCDBD_HUMAN	Protocadherin beta-13	11322959	The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number.

O08839	BIN1_RAT	Myc box-dependent-interacting protein 1	9348539	Amphiphysin heterodimers: potential role in clathrin-mediated endocytosis.

Q12923	PTN13_HUMAN	Tyrosine-protein phosphatase non-receptor type 13	15611135	Crystal structure of the PTPL1/FAP-1 human tyrosine phosphatase mutated in colorectal cancer: evidence for a second phosphotyrosine substrate recognition pocket.

O00255	MEN1_HUMAN	Menin	12874027	Menin associates with FANCD2, a protein involved in repair of DNA damage.

P81910	OR22B_DROME	Odorant receptor 22b	10089887	A spatial map of olfactory receptor expression in the Drosophila antenna.

Q9GYF1	TNNI2_CAEEL	Troponin I 2	14747334	Disruption of Caenorhabditis elegans muscle structure and function caused by mutation of troponin I.

Q9UHQ1	NARF_HUMAN	Nuclear prelamin A recognition factor	10514485	Prenylated prelamin A interacts with Narf, a novel nuclear protein.

O74546	YCV7_SCHPO	Uncharacterized mannosyltransferase C777.07	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q15528	MED22_HUMAN	Mediator of RNA polymerase II transcription subunit 22	12584197	Identification of mammalian Mediator subunits with similarities to yeast Mediator subunits Srb5, Srb6, Med11, and Rox3.

P27809	KRE2_YEAST	Glycolipid 2-alpha-mannosyltransferase	1550992	Glycosylation in Saccharomyces cerevisiae: cloning and characterization of an alpha-1,2-mannosyltransferase structural gene.

Q9R1S9	MK_RAT	Midkine	10683378	Neointima formation in a restenosis model is suppressed in midkine- deficient mice.

P15522	GLCM1_CAMDR	Glycosylation-dependent cell adhesion molecule 1	10531593	Alternative splicing of lactophorin mRNA from lactating mammary gland of the camel (Camelus dromedarius).

Q6P5E4	UGGG1_MOUSE	UDP-glucose:glycoprotein glucosyltransferase 1	11278576	Association between the 15-kDa selenoprotein and UDP- glucose:glycoprotein glucosyltransferase in the endoplasmic reticulum of mammalian cells.

O95251	MYST2_HUMAN	Histone acetyltransferase MYST2	10438470	Histone acetyltransferase HBO1 interacts with the ORC1 subunit of the human initiator protein.

Q9FKW6	FNRL1_ARATH	Ferredoxin--NADP reductase, leaf isozyme 1, chloroplastic	14729914	In-depth analysis of the thylakoid membrane proteome of Arabidopsis thaliana chloroplasts: new proteins, new functions, and a plastid proteome database.

P27882	ERV1_YEAST	Mitochondrial FAD-linked sulfhydryl oxidase ERV1	15989955	A disulfide relay system in the intermembrane space of mitochondria that mediates protein import.

P30561	AHR_MOUSE	Aryl hydrocarbon receptor	12213388	Role of the aryl hydrocarbon receptor in cell cycle regulation.

Q04177	UTP5_YEAST	U3 small nucleolar RNA-associated protein 5	12068309	A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis.

O14119	BSCLH_SCHPO	Seipin homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q24572	CAF1_DROME	Probable histone-binding protein Caf1	15479636	Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes.

Q9Z138	ROR2_MOUSE	Tyrosine-protein kinase transmembrane receptor ROR2	10231392	Spatio-temporally regulated expression of receptor tyrosine kinases, mRor1, mRor2, during mouse development: implications in development and function of the nervous system.

P28331	NDUS1_HUMAN	NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial	1935949	Determination of the cDNA sequence for the human mitochondrial 75-kDa Fe-S protein of NADH-coenzyme Q reductase.

Q969I6	S38A4_HUMAN	Sodium-coupled neutral amino acid transporter 4	11342143	Evidence for the transport of neutral as well as cationic amino acids by ATA3, a novel and liver-specific subtype of amino acid transport system A.

Q10159	MYH1_SCHPO	A/G-specific adenine DNA glycosylase	9737967	Characterization of the recombinant MutY homolog, an adenine DNA glycosylase, from yeast Schizosaccharomyces pombe.

P36952	SPB5_HUMAN	Serpin B5	8290962	Maspin, a serpin with tumor-suppressing activity in human mammary epithelial cells.

P29539	RIF1_YEAST	Telomere length regulator protein RIF1	9710643	Sir proteins, Rif proteins, and Cdc13p bind Saccharomyces telomeres in vivo.

P09060	ODBA_PSEPU	2-oxoisovalerate dehydrogenase subunit alpha	10426958	Crystal structure of 2-oxoisovalerate and dehydrogenase and the architecture of 2-oxo acid dehydrogenase multienzyme complexes.

Q91620	NOD2A_XENLA	Nodal homolog 2-A	9310324	Functional differences among Xenopus nodal-related genes in left- right axis determination.

P23759	PAX7_HUMAN	Paired box protein Pax-7	9339373	The genomic organization and the full coding region of the human PAX7 gene.

Q8BJS4	SUN2_MOUSE	SUN domain-containing protein 2	16380439	Coupling of the nucleus and cytoplasm: role of the LINC complex.

Q96RL1	UIMC1_HUMAN	BRCA1-A complex subunit RAP80	19261746	MERIT40 controls BRCA1-Rap80 complex integrity and recruitment to DNA double-strand breaks.

P46640	KNAT2_ARATH	Homeobox protein knotted-1-like 2	11701881	The Arabidopsis BELL1 and KNOX TALE homeodomain proteins interact through a domain conserved between plants and animals.

Q04900	MUC24_HUMAN	Sialomucin core protein 24	17077324	Endolyn (CD164) modulates the CXCL12-mediated migration of umbilical cord blood CD133+ cells.

Q9NZM5	GSCR2_HUMAN	Glioma tumor suppressor candidate region gene 2 protein	10196275	A novel cellular protein, p60, interacting with both herpes simplex virus 1 regulatory proteins ICP22 and ICP0 is modified in a cell-type- specific manner and is recruited to the nucleus after infection.

Q9UUA7	YHAH_SCHPO	UPF0590 protein C409.17c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9XTN2	IRS1_DROME	Insulin receptor substrate 1	10399915	Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4.

Q6GQT6	SCAP_MOUSE	Sterol regulatory element-binding protein cleavage-activating protein	11358865	SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevation.

P02489	CRYAA_HUMAN	Alpha-crystallin A chain	8943244	Cloning, expression, and chaperone-like activity of human alphaA- crystallin.

P79064	RAD31_SCHPO	DNA damage tolerance protein rad31	9092625	Characterisation of Schizosaccharomyces pombe rad31, a UBA-related gene required for DNA damage tolerance.

Q9P3A7	CDC48_SCHPO	Cell division cycle protein 48	14993272	Lub1 participates in ubiquitin homeostasis and stress response via maintenance of cellular ubiquitin contents in fission yeast.

P32839	BCS1_YEAST	Mitochondrial chaperone BCS1	1327750	BCS1, a novel gene required for the expression of functional Rieske iron-sulfur protein in Saccharomyces cerevisiae.

Q9CR26	VTA1_MOUSE	Vacuolar protein sorting-associated protein VTA1 homolog	15173323	Mammalian class E Vps proteins, SBP1 and mVps2/CHMP2A, interact with and regulate the function of an AAA-ATPase SKD1/Vps4B.

P09457	ATPO_YEAST	ATP synthase subunit 5, mitochondrial	2146269	The gene coding for the yeast oligomycin sensitivity-conferring protein.

O80513	CCU41_ARATH	Cyclin-U4-1	15197472	Molecular characterization of Arabidopsis PHO80-like proteins, a novel class of CDKA;1-interacting cyclins.

O80575	RISB_ARATH	6,7-dimethyl-8-ribityllumazine synthase, chloroplastic	10419541	Plant riboflavin biosynthesis. Cloning, chloroplast localization, expression, purification, and partial characterization of spinach lumazine synthase.

Q9CR24	NUDT8_MOUSE	Nucleoside diphosphate-linked moiety X motif 8, mitochondrial	14651853	Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.

Q9XYT4	ORCH_ORCCA	Orchestin	11772404	Characterization and spatiotemporal expression of orchestin, a gene encoding an ecdysone-inducible protein from a crustacean organic matrix.

Q04806	GTO3_YEAST	Glutathione S-transferase omega-like 3	16936141	A peroxisomal glutathione transferase of Saccharomyces cerevisiae is functionally related to sulfur amino acid metabolism.

Q9H1Y3	OPN3_HUMAN	Opsin-3	10234000	Encephalopsin: a novel mammalian extraretinal opsin discretely localized in the brain.

Q02457	TBF1_YEAST	Protein TBF1	10871401	Identification of high affinity Tbf1p-binding sites within the budding yeast genome.

Q9UQK1	PPR3C_HUMAN	Protein phosphatase 1 regulatory subunit 3C	14532330	Laforin, the dual-phosphatase responsible for Lafora disease, interacts with R5 (PTG), a regulatory subunit of protein phosphatase-1 that enhances glycogen accumulation.

Q9P7D4	ACON2_SCHPO	Probable aconitate hydratase 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O13978	MUG66_SCHPO	Meiotically up-regulated gene 66 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q95YM8	MBLK1_APIME	Mushroom body large-type Kenyon cell-specific protein 1	11829456	DNA-binding properties of Mblk-1, a putative transcription factor from the honeybee.

P22288	GCH1_RAT	GTP cyclohydrolase 1	17057711	GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence.

Q7SY48	HEAT1_DANRE	HEAT repeat-containing protein 1	16531401	Perturbation of rRNA synthesis in the bap28 mutation leads to apoptosis mediated by p53 in the zebrafish central nervous system.

P61586	RHOA_HUMAN	Transforming protein RhoA	10066731	Diacylglycerol kinase theta binds to and is negatively regulated by active RhoA.

P53306	GPI1_YEAST	Phosphatidylinositol N-acetylglucosaminyltransferase subunit GPI1	8910381	Gpi1, a Saccharomyces cerevisiae protein that participates in the first step in glycosylphosphatidylinositol anchor synthesis.

P33076	C2TA_HUMAN	MHC class II transactivator	8402893	Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome).

Q10430	SPC25_SCHPO	Kinetochore protein spc25	15728720	Dissociation of the Nuf2-Ndc80 complex releases centromeres from the spindle-pole body during meiotic prophase in fission yeast.

Q9NWZ8	GEMI8_HUMAN	Gem-associated protein 8	17023415	Gemin8 is required for the architecture and function of the survival motor neuron complex.

P25360	PHO87_YEAST	Inorganic phosphate transporter PHO87	8598055	Two new genes, PHO86 and PHO87, involved in inorganic phosphate uptake in Saccharomyces cerevisiae.

P50086	PSD10_YEAST	Probable 26S proteasome regulatory subunit p28	19412159	Chaperone-mediated pathway of proteasome regulatory particle assembly.

Q04093	YD444_YEAST	Putative lipase YDR444W	14562095	Global analysis of protein localization in budding yeast.

Q9QZQ0	NPAS3_MOUSE	Neuronal PAS domain-containing protein 3	15347806	Behavioral and regulatory abnormalities in mice deficient in the NPAS1 and NPAS3 transcription factors.

P51531	SMCA2_HUMAN	Probable global transcription activator SNF2L2	8208605	Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor.

Q9H2J7	S6A15_HUMAN	Orphan sodium- and chloride-dependent neurotransmitter transporter NTT73	11112352	Cloning and characterization of human NTT5 and v7-3: two orphan transporters of the Na(+)/Cl(-)-dependent neurotransmitter transporter gene family.

P54259	ATN1_HUMAN	Atrophin-1	9647693	Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins.

P38114	TBS1_YEAST	Uncharacterized transcriptional regulatory protein TBS1	14562095	Global analysis of protein localization in budding yeast.

Q92207	HOG1_CANAL	Mitogen-activated protein kinase HOG1	15229284	A conserved stress-activated protein kinase regulates a core stress response in the human pathogen Candida albicans.

O59825	TDG_SCHPO	G/U mismatch-specific uracil DNA glycosylase	12711670	The versatile thymine DNA-glycosylase: a comparative characterization of the human, Drosophila and fission yeast orthologs.

Q15276	RABE1_HUMAN	Rab GTPase-binding effector protein 1	8521472	Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion.

Q84MC7	PYL9_ARATH	Abscisic acid receptor PYL9	19407143	Regulators of PP2C phosphatase activity function as abscisic acid sensors.

Q15828	CYTM_HUMAN	Cystatin-M	8995380	Identification, cloning, and characterization of cystatin M, a novel cysteine proteinase inhibitor, down-regulated in breast cancer.

O95433	AHSA1_HUMAN	Activator of 90 kDa heat shock protein ATPase homolog 1	12504007	Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1.

Q9UBR1	BUP1_HUMAN	Beta-ureidopropionase	15385443	Beta-ureidopropionase deficiency: an inborn error of pyrimidine degradation associated with neurological abnormalities.

Q54WZ2	VACB_DICDI	Vacuolin-B	9394012	Targeted gene disruption reveals a role for vacuolin B in the late endocytic pathway and exocytosis.

P23396	RS3_HUMAN	40S ribosomal protein S3	1712897	Ribosomal protein genes are overexpressed in colorectal cancer: isolation of a cDNA clone encoding the human S3 ribosomal protein.

Q8ML92	AVE_DROME	Protein aveugle	16600911	The novel SAM domain protein Aveugle is required for Raf activation in the Drosophila EGF receptor signaling pathway.

P29674	LHX1_XENLA	LIM/homeobox protein Lhx1	12710967	Molecular link in the sequential induction of the Spemann organizer: direct activation of the cerberus gene by Xlim-1, Xotx2, Mix.1, and Siamois, immediately downstream from Nodal and Wnt signaling.

Q6IE81	JADE1_HUMAN	Protein Jade-1	16387653	ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.

Q9C0W0	MIS15_SCHPO	Kinetochore protein mis15	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q15834	CC85B_HUMAN	Coiled-coil domain-containing protein 85B	17014843	DIPA, which can localize to the centrosome, associates with p78/MCRS1/MSP58 and acts as a repressor of gene transcription.

O49840	APK2B_ARATH	Protein kinase 2B, chloroplastic	17644812	A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome.

Q13315	ATM_HUMAN	Serine-protein kinase ATM	7792600	A single ataxia telangiectasia gene with a product similar to PI-3 kinase.

Q924N4	S12A6_MOUSE	Solute carrier family 12 member 6	11246162	Localization of the K(+)-Cl(-) cotransporter, KCC3, in the central and peripheral nervous systems: expression in the choroid plexus, large neurons and white matter tracts.

Q9UJX4	APC5_HUMAN	Anaphase-promoting complex subunit 5	18485873	Mechanism of ubiquitin-chain formation by the human anaphase- promoting complex.

Q05192	FTF1B_DROME	Nuclear hormone receptor FTZ-F1 beta	8164672	The Drosophila nuclear receptors FTZ-F1 alpha and FTZ-F1 beta compete as monomers for binding to a site in the fushi tarazu gene.

Q62924	AKA11_RAT	A-kinase anchor protein 11	8621616	Cloning and characterization of a novel A-kinase anchoring protein. AKAP 220, association with testicular peroxisomes.

Q15126	PMVK_HUMAN	Phosphomevalonate kinase	10191291	Characterization of phosphomevalonate kinase: chromosomal localization, regulation, and subcellular targeting.

Q9Z1S8	GAB2_MOUSE	GRB2-associated-binding protein 2	11449275	Essential role for Gab2 in the allergic response.

P19235	EPOR_HUMAN	Erythropoietin receptor	1668606	Cloning of the human erythropoietin receptor gene.

Q9BXA7	TSSK1_HUMAN	Testis-specific serine/threonine-protein kinase 1	15733851	Identification of the sucrose non-fermenting related kinase SNRK, as a novel LKB1 substrate.

Q86A84	MPPA1_DICDI	Mitochondrial-processing peptidase subunit alpha-1	18603769	Antisense RNA inhibition of the beta subunit of the Dictyostelium discoideum mitochondrial processing peptidase induces the expression of mitochondrial proteins.

P45380	S26A1_RAT	Sulfate anion transporter 1	8300633	Functional expression cloning of the canalicular sulfate transport system of rat hepatocytes.

P47992	XCL1_HUMAN	Lymphotactin	7602097	Molecular cloning and functional characterization of human lymphotactin.

P58451	VARF_VIOAR	Varv peptide F	12477048	Cyclotides: a novel type of cytotoxic agents.

O94527	YBU3_SCHPO	Uncharacterized WD repeat-containing protein C609.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P0A9A6	FTSZ_ECOLI	Cell division protein ftsZ	1528267	Escherichia coli cell-division gene ftsZ encodes a novel GTP-binding protein.

P01594	KV102_HUMAN	Ig kappa chain V-I region AU	5028201	Rule of antibody structure. The primary structure of a monoclonal immunoglobulin L-chain of the kappa-type, subgroup I (Bence-Jones protein Au).

Q91V08	CLC2D_MOUSE	C-type lectin domain family 2 member D	12374791	Osteoclast inhibitory lectin, a family of new osteoclast inhibitors.

Q9LXS6	CISY2_ARATH	Citrate synthase 2, peroxisomal	15923350	Arabidopsis peroxisomal citrate synthase is required for fatty acid respiration and seed germination.

Q8VID6	PDE11_RAT	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	11502204	Identification of rat cyclic nucleotide phosphodiesterase 11A (PDE11A): comparison of rat and human PDE11A splicing variants.

P84804	CRV23_NAJHH	Cysteine-rich venom protein 23	15670767	Cobra venom contains a pool of cysteine-rich secretory proteins.

Q9H2C0	GAN_HUMAN	Gigaxonin	12147674	Microtubule-associated protein 1B: a neuronal binding partner for gigaxonin.

Q8IU99	CAHM1_HUMAN	Calcium homeostasis modulator protein 1	18585350	A polymorphism in CALHM1 influences Ca2+ homeostasis, Abeta levels, and Alzheimer's disease risk.

Q9VU87	VPS36_DROME	Vacuolar protein-sorting-associated protein 36	19132102	Common and distinct genetic properties of ESCRT-II components in Drosophila.

O35625	AXN1_MOUSE	Axin-1	9230313	The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation.

Q5NBX1	COBL_MOUSE	Protein cordon-bleu	14512015	Cordon-bleu is a conserved gene involved in neural tube formation.

Q05707	COEA1_HUMAN	Collagen alpha-1(XIV) chain	2187872	Undulin, an extracellular matrix glycoprotein associated with collagen fibrils.

O74978	YQL5_SCHPO	Uncharacterized RNA-binding protein C1827.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q91YD4	TRPM2_MOUSE	Transient receptor potential cation channel subfamily M member 2	11804595	LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death.

Q91619	NODAL_XENLA	Nodal homolog	17123501	Multiple functions of Cerberus cooperate to induce heart downstream of Nodal.

O00329	PK3CD_HUMAN	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform	9235916	p110delta, a novel phosphatidylinositol 3-kinase catalytic subunit that associates with p85 and is expressed predominantly in leukocytes.

P28650	PURA1_MOUSE	Adenylosuccinate synthetase isozyme 1	1939273	Molecular cloning and expression of a mouse muscle cDNA encoding adenylosuccinate synthetase.

P32502	EI2BB_YEAST	Translation initiation factor eIF-2B subunit beta	8506384	A protein complex of translational regulators of GCN4 mRNA is the guanine nucleotide-exchange factor for translation initiation factor 2 in yeast.

P20827	EFNA1_HUMAN	Ephrin-A1	2233719	A novel immediate-early response gene of endothelium is induced by cytokines and encodes a secreted protein.

Q92813	IOD2_HUMAN	Type II iodothyronine deiodinase	8755651	Cloning of the mammalian type II iodothyronine deiodinase. A selenoprotein differentially expressed and regulated in human and rat brain and other tissues.

O88182	FGF18_RAT	Fibroblast growth factor 18	9660775	Structure and expression of the mRNA encoding a novel fibroblast growth factor, FGF-18.

A2RTF1	CTSRB_MOUSE	Cation channel sperm-associated protein subunit beta	17478420	CatSperbeta, a novel transmembrane protein in the CatSper channel complex.

P49040	SUS1_ARATH	Sucrose synthase 1	8220487	Expression of an Arabidopsis sucrose synthase gene indicates a role in metabolization of sucrose both during phloem loading and in sink organs.

Q12045	VIK1_YEAST	Spindle pole body-associated protein VIK1	10087265	Differential regulation of the Kar3p kinesin-related protein by two associated proteins, Cik1p and Vik1p.

P53032	SUT1_YEAST	Sterol uptake protein 1	11401714	SUT1p interaction with Cyc8p(Ssn6p) relieves hypoxic genes from Cyc8p-Tup1p repression in Saccharomyces cerevisiae.

Q6VGS5	DAPLE_MOUSE	Protein Daple	14750955	Identification and characterization of a novel Dvl-binding protein that suppresses Wnt signalling pathway.

P29547	EF1G1_YEAST	Elongation factor 1-gamma 1	8465602	Cloning and genetic characterization of a calcium- and phospholipid- binding protein from Saccharomyces cerevisiae that is homologous to translation elongation factor-1 gamma.

P42641	OBG_ECOLI	GTPase ObgE/CgtA	19555460	The ObgE/CgtA GTPase influences the stringent response to amino acid starvation in Escherichia coli.

A2V7M9	PGAP3_CRIGR	Post-GPI attachment to proteins factor 3	17314402	Fatty acid remodeling of GPI-anchored proteins is required for their raft association.

P12081	SYHC_HUMAN	Histidyl-tRNA synthetase, cytoplasmic	7755634	A novel gene oriented in a head-to-head configuration with the human histidyl-tRNA synthetase (HRS) gene encodes an mRNA that predicts a polypeptide homologous to HRS.

P08111	L2GL_DROME	Lethal(2) giant larvae protein	12545176	Dlg, Scrib and Lgl regulate neuroblast cell size and mitotic spindle asymmetry.

Q02821	IMA1_YEAST	Importin subunit alpha	7622450	Identification of a yeast karyopherin heterodimer that targets import substrate to mammalian nuclear pore complexes.

P62875	RPAB5_HUMAN	DNA-directed RNA polymerases I, II, and III subunit RPABC5	8524256	Six human RNA polymerase subunits functionally substitute for their yeast counterparts.

Q9HGN7	SEC63_SCHPO	Translocation protein sec63	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O24606	EIN3_ARATH	Protein ETHYLENE INSENSITIVE 3	9215635	Activation of the ethylene gas response pathway in Arabidopsis by the nuclear protein ETHYLENE-INSENSITIVE3 and related proteins.

Q93070	NAR4_HUMAN	Ecto-ADP-ribosyltransferase 4	9119374	Two novel human members of an emerging mammalian gene family related to mono-ADP-ribosylating bacterial toxins.

O59812	G6PD2_SCHPO	Probable glucose-6-phosphate 1-dehydrogenase C794.01c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UBP0	SPAST_HUMAN	Spastin	16815977	Interaction of two hereditary spastic paraplegia gene products, spastin and atlastin, suggests a common pathway for axonal maintenance.

Q9UKE5	TNIK_HUMAN	TRAF2 and NCK-interacting protein kinase	10521462	TNIK, a novel member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and regulates the cytoskeleton.

O75431	MTX2_HUMAN	Metaxin-2	10381257	Metaxin 1 interacts with metaxin 2, a novel related protein associated with the mammalian mitochondrial outer membrane.

Q44338	FLGG_AGRT5	Flagellar basal-body rod protein flgG	9161424	Isolation and characterisation of a linked cluster of genes from Agrobacterium tumefaciens encoding proteins involved in flagellar basal-body structure.

Q8CGB3	UACA_MOUSE	Uveal autoantigen with coiled-coil domains and ankyrin repeats	14961764	Nucling mediates apoptosis by inhibiting expression of galectin-3 through interference with nuclear factor kappaB signalling.

Q6B9X6	VWKA_DICDI	Alpha-protein kinase vwkA	18381083	Determinants for substrate phosphorylation by Dictyostelium myosin II heavy chain kinases A and B and eukaryotic elongation factor-2 kinase.

P0A9F3	CYSB_ECOLI	HTH-type transcriptional regulator cysB	2182030	Analysis of the Escherichia coli K-12 cysB gene and its product using the method of gene fusion.

O94533	YCA6_SCHPO	Uncharacterized WD repeat-containing protein C895.06	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P41567	EIF1_HUMAN	Eukaryotic translation initiation factor 1	7904817	Expressed sequence tags identify a human isolog of the suil translation initiation factor.

P46926	GNPI1_HUMAN	Glucosamine-6-phosphate isomerase 1	9714720	The human glucosamine-6-phosphate deaminase gene: cDNA cloning and expression, genomic organization and chromosomal localization.

Q02890	PNG1_YEAST	Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	10831608	PNG1, a yeast gene encoding a highly conserved peptide:N-glycanase.

P12104	FABPI_HUMAN	Fatty acid-binding protein, intestinal	7883976	An amino acid substitution in the human intestinal fatty acid binding protein is associated with increased fatty acid binding, increased fat oxidation, and insulin resistance.

Q13564	ULA1_HUMAN	NEDD8-activating enzyme E1 regulatory subunit	15361859	A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8.

P01778	HV317_HUMAN	Ig heavy chain V-III region ZAP	4522793	Variable region sequences of five human immunoglobulin heavy chains of the VH3 subgroup: definitive identification of four heavy chain hypervariable regions.

P33947	ERD22_HUMAN	ER lumen protein retaining receptor 2	1325562	Sequence of a second human KDEL receptor.

P87299	MUG74_SCHPO	Meiotically up-regulated gene 74 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q91372	DDX4_XENLA	Probable ATP-dependent RNA helicase DDX4	9338598	Involvement of the protein of Xenopus vasa homolog (Xenopus vasa-like gene 1, XVLG1) in the differentiation of primordial germ cells.

Q9Y235	ABEC2_HUMAN	Probable C->U-editing enzyme APOBEC-2	10403781	APOBEC-2, a cardiac- and skeletal muscle-specific member of the cytidine deaminase supergene family.

P53704	GFA1_CANAL	Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	8636033	Isolation and characterization of the GFA1 gene encoding the glutamine:fructose-6-phosphate amidotransferase of Candida albicans.

Q8LE52	DHAR3_ARATH	Glutathione S-transferase DHAR3, chloroplastic	12077129	Functional divergence in the glutathione transferase superfamily in plants. Identification of two classes with putative functions in redox homeostasis in Arabidopsis thaliana.

P54857	TGL2_YEAST	Lipase 2	9544243	The Saccharomyces cerevisiae TGL2 gene encodes a protein with lipolytic activity and can complement an Escherichia coli diacylglycerol kinase disruptant.

Q9Y2R2	PTN22_HUMAN	Tyrosine-protein phosphatase non-receptor type 22	10068674	Cloning and characterization of a lymphoid-specific, inducible human protein tyrosine phosphatase, Lyp.

Q9LNR3	LOX3_ARATH	Lipoxygenase 3, chloroplastic	18949503	Diversity of the enzymatic activity in the lipoxygenase gene family of Arabidopsis thaliana.

Q9C5J6	IPT9_ARATH	tRNA dimethylallyltransferase 9	17062755	Roles of Arabidopsis ATP/ADP isopentenyltransferases and tRNA isopentenyltransferases in cytokinin biosynthesis.

P34820	BMP8B_HUMAN	Bone morphogenetic protein 8B	1460021	Osteogenic protein-2. A new member of the transforming growth factor- beta superfamily expressed early in embryogenesis.

P32521	PAN1_YEAST	Actin cytoskeleton-regulatory complex protein PAN1	8756649	The EH-domain-containing protein Pan1 is required for normal organization of the actin cytoskeleton in Saccharomyces cerevisiae.

Q12309	CLF1_YEAST	Pre-mRNA-splicing factor CLF1	11105756	Functional analyses of interacting factors involved in both pre-mRNA splicing and cell cycle progression in Saccharomyces cerevisiae.

P32521	PAN1_YEAST	Actin cytoskeleton-regulatory complex protein PAN1	14622601	A pathway for association of receptors, adaptors, and actin during endocytic internalization.

Q9NRC8	SIRT7_HUMAN	NAD-dependent deacetylase sirtuin-7	19174463	Involvement of SIRT7 in resumption of rDNA transcription at the exit from mitosis.

O22265	SR43C_ARATH	Signal recognition particle 43 kDa protein, chloroplastic	11306572	Functional analysis of the protein-interacting domains of chloroplast SRP43.

Q99104	MYO5A_MOUSE	Myosin-Va	1996138	Novel myosin heavy chain encoded by murine dilute coat colour locus.

P11655	SEC12_YEAST	Guanine nucleotide-exchange factor SEC12	8707815	Endoplasmic reticulum localization of Sec12p is achieved by two mechanisms: Rer1p-dependent retrieval that requires the transmembrane domain and Rer1p-independent retention that involves the cytoplasmic domain.

P40343	VPS27_YEAST	Vacuolar protein sorting-associated protein 27	17101773	Involvement of specific COPI subunits in protein sorting from the late endosome to the vacuole in yeast.

D0EXD3	AFP_PENCH	Antifungal protein	19914321	Characterization of the novel antifungal protein PgAFP and the encoding gene of Penicillium chrysogenum.

Q03667	MIC17_YEAST	Mitochondrial intermembrane space cysteine motif-containing protein MIC17	17095012	Novel mitochondrial intermembrane space proteins as substrates of the MIA import pathway.

Q9M276	ATB12_ARATH	Homeobox-leucine zipper protein ATHB-12	16055682	Homeodomain leucine zipper class I genes in Arabidopsis. Expression patterns and phylogenetic relationships.

P97290	IC1_MOUSE	Plasma protease C1 inhibitor	9199246	The sequence of a cDNA encoding functional murine C1-inhibitor protein.

Q04458	HFD1_YEAST	Putative fatty aldehyde dehydrogenase HFD1	16689936	Integral membrane proteins in the mitochondrial outer membrane of Saccharomyces cerevisiae.

Q00613	HSF1_HUMAN	Heat shock factor protein 1	16278218	Phosphorylation of HSF1 by MAPK-activated protein kinase 2 on serine 121, inhibits transcriptional activity and promotes HSP90 binding.

Q55AR3	TBG_DICDI	Tubulin gamma chain	9275182	Centrosome positioning and directionality of cell movements.

Q08850	STX4_RAT	Syntaxin-4	7690687	The syntaxin family of vesicular transport receptors.

P32830	TIM12_YEAST	Mitochondrial import inner membrane translocase subunit TIM12	9495346	Carrier protein import into mitochondria mediated by the intermembrane proteins Tim10/Mrs11 and Tim12/Mrs5.

Q9FFK8	NFXL2_ARATH	NF-X1-type zinc finger protein NFXL2	16905136	The AtNFXL1 gene encodes a NF-X1 type zinc finger protein required for growth under salt stress.

Q05776	UPS1_YEAST	Protein UPS1	14562095	Global analysis of protein localization in budding yeast.

P36534	RM40_YEAST	54S ribosomal protein L40, mitochondrial	12392552	Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components.

Q9WUP1	RAMP3_MOUSE	Receptor activity-modifying protein 3	10854696	Mouse receptor-activity-modifying proteins 1, -2 and -3: amino acid sequence, expression and function.

Q6PR54	RIF1_MOUSE	Telomere-associated protein RIF1	15042697	Identification and characterisation of mRif1: a mouse telomere- associated protein highly expressed in germ cells and embryo-derived pluripotent stem cells.

Q9ESP5	FEZF2_MOUSE	Fez family zinc finger protein 2	16314561	Zfp312 is required for subcortical axonal projections and dendritic morphology of deep-layer pyramidal neurons of the cerebral cortex.

O59716	YBH8_SCHPO	Uncharacterized protein C3B8.8	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P04745	AMY1_HUMAN	Alpha-amylase 1	2423416	Primary structure of human salivary alpha-amylase gene.

O14494	LPP1_HUMAN	Lipid phosphate phosphohydrolase 1	9468526	Identification of the phosphatidic acid phosphatase type 2a isozyme as an androgen-regulated gene in the human prostatic Adenocarcinoma cell line LNCaP.

Q91ZD4	VANG2_MOUSE	Vang-like protein 2	11440971	Cardiovascular defects associated with abnormalities in midline development in the loop-tail mouse mutant.

O75604	UBP2_HUMAN	Ubiquitin carboxyl-terminal hydrolase 2	19917254	Suppression of cancer cell growth by promoting cyclin D1 degradation.

P42283	LOLA1_DROME	Longitudinals lacking protein, isoform G	12538650	A developmentally regulated splice variant from the complex lola locus encoding multiple different zinc finger domain proteins interacts with the chromosomal kinase JIL-1.

O70373	XIRP1_MOUSE	Xin actin-binding repeat-containing protein 1	12203715	Localization of the novel Xin protein to the adherens junction complex in cardiac and skeletal muscle during development.

P20095	PRP2_YEAST	Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2	8112302	The splicing factor PRP2, a putative RNA helicase, interacts directly with pre-mRNA.

P34579	UNC47_CAEEL	Vesicular GABA transporter	9349821	Identification and characterization of the vesicular GABA transporter.

P54098	DPOG1_HUMAN	DNA polymerase subunit gamma-1	9034326	Mitochondrial DNA polymerases from yeast to man: a new family of polymerases.

Q9USU8	NGG1_SCHPO	Chromatin-remodeling complexes subunit ngg1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q704S8	CACP_RAT	Carnitine O-acetyltransferase	15155769	Redesign of carnitine acetyltransferase specificity by protein engineering.

Q13976	KGP1_HUMAN	cGMP-dependent protein kinase 1	2792381	Molecular cloning and predicted full-length amino acid sequence of the type I beta isozyme of cGMP-dependent protein kinase from human placenta. Tissue distribution and developmental changes in rat.

P22146	GAS1_YEAST	1,3-beta-glucanosyltransferase GAS1	10809732	Glycosylphosphatidylinositol-anchored glucanosyltransferases play an active role in the biosynthesis of the fungal cell wall.

Q8VIH1	NOBOX_MOUSE	Homeobox protein NOBOX	15326356	NOBOX deficiency disrupts early folliculogenesis and oocyte-specific gene expression.

P18283	GPX2_HUMAN	Glutathione peroxidase 2	8428933	Expression, characterization, and tissue distribution of a new cellular selenium-dependent glutathione peroxidase, GSHPx-GI.

O75832	PSD10_HUMAN	26S proteasome non-ATPase regulatory subunit 10	19490896	Assembly pathway of the Mammalian proteasome base subcomplex is mediated by multiple specific chaperones.

O93428	CATD_CHIHA	Cathepsin D	10209280	Cathepsin D from the liver of the Antarctic icefish Chionodraco hamatus exhibits unusual activity and stability at high temperatures.

P49407	ARRB1_HUMAN	Beta-arrestin-1	16325578	A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription.

P50116	S10A9_RAT	Protein S100-A9	8343166	Expression and cloning of migration inhibitory factor-related protein (MRP)8 and MRP14 in arthritis-susceptible rats.

P36589	CDC14_SCHPO	Cell division control protein 14	11384993	Interaction between the noncatalytic region of Sid1p kinase and Cdc14p is required for full catalytic activity and localization of Sid1p.

P27797	CALR_HUMAN	Calreticulin	11149926	Calreticulin is a receptor for nuclear export.

Q84JU6	HOS1_ARATH	E3 ubiquitin-protein ligase HOS1	11297514	The Arabidopsis HOS1 gene negatively regulates cold signal transduction and encodes a RING finger protein that displays cold- regulated nucleo-cytoplasmic partitioning.

P49767	VEGFC_HUMAN	Vascular endothelial growth factor C	8617204	A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases.

P25586	KRR1_YEAST	Ribosomal RNA assembly protein KRR1	11996121	The KRR1 gene encodes a protein required for 18S rRNA synthesis and 40S ribosomal subunit assembly in Saccharomyces cerevisiae.

Q17905	NHR28_CAEEL	Nuclear hormone receptor family member nhr-28	15983867	Explosive lineage-specific expansion of the orphan nuclear receptor HNF4 in nematodes.

O54329	LANA_STRMU	Lantibiotic mutacin-2	8592997	Mutacin II, a bactericidal lantibiotic from Streptococcus mutans.

Q96DB2	HDA11_HUMAN	Histone deacetylase 11	11948178	Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family.

P84269	DAH53_LITDA	Dahlein-5.3	11555873	Bioactive dahlein peptides from the skin secretions of the Australian aquatic frog Litoria dahlii: sequence determination by electrospray mass spectrometry.

Q6ZQM0	RFFL_MOUSE	E3 ubiquitin-protein ligase rififylin	15229288	Over-expression of Rififylin, a new RING finger and FYVE-like domain- containing protein, inhibits recycling from the endocytic recycling compartment.

Q9R1V6	ADA22_MOUSE	Disintegrin and metalloproteinase domain-containing protein 22	15876356	Ataxia and peripheral nerve hypomyelination in ADAM22-deficient mice.

P35579	MYH9_HUMAN	Myosin-9	1912569	Cellular myosin heavy chain in human leukocytes: isolation of 5' cDNA clones, characterization of the protein, chromosomal localization, and upregulation during myeloid differentiation.

Q9NQ94	A1CF_HUMAN	APOBEC1 complementation factor	10669759	Molecular cloning of APOBEC-1 complementation factor, a novel RNA- binding protein involved in the editing of apolipoprotein B mRNA.

O04722	SUT21_ARATH	Sulfate transporter 2.1	9380766	Regulation of sulfur assimilation in higher plants: a sulfate transporter induced in sulfate-starved roots plays a central role in Arabidopsis thaliana.

Q10271	ARB2_SCHPO	Argonaute-binding protein 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q03750	TAF8_YEAST	Transcription initiation factor TFIID subunit 8	10788514	Identification of two novel TAF subunits of the yeast Saccharomyces cerevisiae TFIID complex.

P43403	ZAP70_HUMAN	Tyrosine-protein kinase ZAP-70	7528772	ZAP-70 binding specificity to T cell receptor tyrosine-based activation motifs: the tandem SH2 domains of ZAP-70 bind distinct tyrosine-based activation motifs with varying affinity.

P24473	GSTK1_RAT	Glutathione S-transferase kappa 1	8920976	Glutathione S-transferase class Kappa: characterization by the cloning of rat mitochondrial GST and identification of a human homologue.

P23694	PRZN_SERMA	Serralysin	16391997	Purification and properties of a novel insecticidal protein from the locust pathogen Serratia marcescens HR-3.

Q63941	RAB3B_RAT	Ras-related protein Rab-3B	9245721	Differential expression of Rab3 isoforms during differentiation of pancreatic acinar cell line AR42J.

P13677	KPC2_DROME	Protein kinase C, eye isozyme	11342563	The second PDZ domain of INAD is a type I domain involved in binding to eye protein kinase C. Mutational analysis and naturally occurring variants.

Q04373	PUF6_YEAST	Pumilio homology domain family member 6	14562095	Global analysis of protein localization in budding yeast.

P70549	NAC3_RAT	Sodium/calcium exchanger 3	8798769	Cloning of a third mammalian Na+-Ca2+ exchanger, NCX3.

P51981	AEEP_ECOLI	L-Ala-D/L-Glu epimerase	11747447	Evolution of enzymatic activities in the enolase superfamily: functional assignment of unknown proteins in Bacillus subtilis and Escherichia coli as L-Ala-D/L-Glu epimerases.

Q9UM13	APC10_HUMAN	Anaphase-promoting complex subunit 10	10318877	Characterization of the DOC1/APC10 subunit of the yeast and the human anaphase-promoting complex.

Q9Y5P4	C43BP_HUMAN	Collagen type IV alpha-3-binding protein	16895911	Efficient trafficking of ceramide from the endoplasmic reticulum to the Golgi apparatus requires a VAMP-associated protein-interacting FFAT motif of CERT.

Q13835	PKP1_HUMAN	Plakophilin-1	7527055	Band 6 protein, a major constituent of desmosomes from stratified epithelia, is a novel member of the armadillo multigene family.

Q07540	FRDA_YEAST	Frataxin homolog, mitochondrial	9180083	Regulation of mitochondrial iron accumulation by Yfh1p, a putative homolog of frataxin.

O88291	ZN326_MOUSE	Zinc finger protein 326	9809746	Cloning and characterization of a novel zinc finger protein that associates with nuclear matrix.

P03872	REP2_YEAST	Partitioning protein REP2	9393716	The 2 micrometer-plasmid-encoded Rep1 and Rep2 proteins interact with each other and colocalize to the Saccharomyces cerevisiae nucleus.

Q9USS2	PPK29_SCHPO	Serine/threonine-protein kinase ppk29	15821139	Systematic deletion analysis of fission yeast protein kinases.

A1E959	ODAM_HUMAN	Odontogenic ameloblast-associated protein	14647039	Calcifying epithelial odontogenic (Pindborg) tumor-associated amyloid consists of a novel human protein.

Q9Y2K2	SIK3_HUMAN	Serine/threonine-protein kinase SIK3	16306228	14-3-3 cooperates with LKB1 to regulate the activity and localization of QSK and SIK.

Q07655	WHI4_YEAST	Protein WHI4	11290704	Isolation and characterization of WHI3, a size-control gene of Saccharomyces cerevisiae.

P38688	SRP72_YEAST	Signal recognition particle subunit SRP72	7925282	Subunits of the Saccharomyces cerevisiae signal recognition particle required for its functional expression.

O60152	UBR1_SCHPO	E3 ubiquitin-protein ligase ubr1	11702950	Phosphorylation of Mei2 and Ste11 by Pat1 kinase inhibits sexual differentiation via ubiquitin proteolysis and 14-3-3 protein in fission yeast.

Q5SV77	GGNB2_MOUSE	Gametogenetin-binding protein 2	11728448	Dioxin induces a novel nuclear factor, DIF-3, that is implicated in spermatogenesis.

Q92748	THRSP_HUMAN	Thyroid hormone-inducible hepatic protein	9003802	Cloning and initial characterization of human and mouse Spot 14 genes.

Q91ZD4	VANG2_MOUSE	Vang-like protein 2	15456783	Independent mutations in mouse Vangl2 that cause neural tube defects in looptail mice impair interaction with members of the Dishevelled family.

Q47129	FEAR_ECOLI	Transcriptional activator feaR	9043126	2-phenylethylamine catabolism by Escherichia coli K-12: gene organization and expression.

Q8IVS8	GLCTK_HUMAN	Glycerate kinase	16753811	Isolation and characterization of the human D-glyceric acidemia related glycerate kinase gene GLYCTK1 and its alternatively splicing variant GLYCTK2.

P39013	END3_YEAST	Actin cytoskeleton-regulatory complex protein END3	15944351	End3p-mediated endocytosis is required for spore wall formation in Saccharomyces cerevisiae.

Q9Y2D2	S35A3_HUMAN	UDP-N-acetylglucosamine transporter	10393322	Molecular cloning and functional expression of the human Golgi UDP-N- acetylglucosamine transporter.

Q9DEN4	FXD3A_XENLA	Forkhead box protein D3-A	11493569	Requirement of FoxD3-class signaling for neural crest determination in Xenopus.

Q13822	ENPP2_HUMAN	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	8579579	Cloning, chromosomal localization, and tissue expression of autotaxin from human teratocarcinoma cells.

P25724	NANOS_DROME	Protein nanos	11060247	Nanos interacts with cup in the female germline of Drosophila.

Q70KY3	LAC1_MELAO	Laccase-1	12111146	Purification and characterisation of a novel laccase from the ascomycete Melanocarpus albomyces.

P32298	GRK4_HUMAN	G protein-coupled receptor kinase 4	1338872	A novel G protein-coupled receptor kinase gene cloned from 4p16.3.

O14224	GDIR_SCHPO	Rho GDP-dissociation inhibitor	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q03655	GAS3_YEAST	Probable 1,3-beta-glucanosyltransferase GAS3	17397106	The Gas family of proteins of Saccharomyces cerevisiae: characterization and evolutionary analysis.

O34453	NOSO_BACSU	Nitric oxide synthase oxygenase	11856757	Direct evidence for nitric oxide production by a nitric-oxide synthase-like protein from Bacillus subtilis.

Q06089	YP098_YEAST	Uncharacterized mitochondrial outer membrane protein YPR098C	16407407	Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins.

Q9P794	RU1C_SCHPO	U1 small nuclear ribonucleoprotein C	17264129	Proteomic analysis of the U1 snRNP of Schizosaccharomyces pombe reveals three essential organism-specific proteins.

Q60972	RBBP4_MOUSE	Histone-binding protein RBBP4	9702189	SAP30, a component of the mSin3 corepressor complex involved in N- CoR-mediated repression by specific transcription factors.

P36365	FMO1_RAT	Dimethylaniline monooxygenase [N-oxide-forming] 1	8504165	Rat liver flavin-containing monooxygenase (FMO): cDNA cloning and expression in yeast.

Q8WXG6	MADD_HUMAN	MAP kinase-activating death domain protein	14735464	Antisense abrogation of DENN expression induces apoptosis of leukemia cells in vitro, causes tumor regression in vivo and alters the transcription of genes involved in apoptosis and the cell cycle.

Q6TPH1	PPA23_ARATH	Purple acid phosphatase 23	16244908	Expression patterns of purple acid phosphatase genes in Arabidopsis organs and functional analysis of AtPAP23 predominantly transcribed in flower.

O93590	ZAX_XENLA	Homeobox protein zampogna	10022957	The Xenopus bagpipe-related homeobox gene zampogna is expressed in the pharyngeal endoderm and the visceral musculature of the midgut.

Q9C9M7	CDKD2_ARATH	Cyclin-dependent kinase D-2	12527363	Differential phosphorylation activities of CDK-activating kinases in Arabidopsis thaliana.

O75530	EED_HUMAN	Polycomb protein EED	16357870	The Polycomb group protein EZH2 directly controls DNA methylation.

Q09884	DCR1_SCHPO	Protein Dicer	15907173	Expression and purification of the carboxyl terminus domain of Schizosaccharomyces pombe dicer in Escherichia coli.

Q9M9X4	NFYA2_ARATH	Nuclear transcription factor Y subunit A-2	9662544	Multiple genes encoding the conserved CCAAT-box transcription factor complex are expressed in Arabidopsis.

Q680I0	ORTH5_ARATH	E3 ubiquitin-protein ligase ORTHRUS 5	18643997	ORTH/VIM proteins that regulate DNA methylation are functional ubiquitin E3 ligases.

P08539	GPA1_YEAST	Guanine nucleotide-binding protein alpha-1 subunit	2105453	Stoichiometry of G protein subunits affects the Saccharomyces cerevisiae mating pheromone signal transduction pathway.

P85053	RNS2C_RANSV	Ranatuerin-2SEc	16386333	Histamine-releasing and antimicrobial peptides from the skin secretions of the dusky gopher frog, Rana sevosa.

O82390	ANTR1_ARATH	Sodium-dependent phosphate transport protein 1, chloroplastic	18353780	Arabidopsis ANTR1 is a thylakoid Na+-dependent phosphate transporter: functional characterization in Escherichia coli.

A8CL69	PBAN_APIME	PBAN-type neuropeptides	17068263	From the genome to the proteome: uncovering peptides in the Apis brain.

Q24572	CAF1_DROME	Probable histone-binding protein Caf1	9419341	Drosophila NURF-55, a WD repeat protein involved in histone metabolism.

Q9WTU3	SCN8A_MOUSE	Sodium channel protein type 8 subunit alpha	7670495	Mutation of a new sodium channel gene, Scn8a, in the mouse mutant 'motor endplate disease'.

Q9BSI4	TINF2_HUMAN	TERF1-interacting nuclear factor 2	16880378	A critical role for TPP1 and TIN2 interaction in high-order telomeric complex assembly.

P33754	SEC66_YEAST	Translocation protein SEC66	8257795	Structural and functional characterization of Sec66p, a new subunit of the polypeptide translocation apparatus in the yeast endoplasmic reticulum.

P48960	CD97_HUMAN	CD97 antigen	8955192	CD97 is a processed, seven-transmembrane, heterodimeric receptor associated with inflammation.

Q96T49	PP16B_HUMAN	Protein phosphatase 1 regulatory inhibitor subunit 16B	12055102	TIMAP, a novel CAAX box protein regulated by TGF-beta1 and expressed in endothelial cells.

P38484	INGR2_HUMAN	Interferon gamma receptor 2	8910544	The structure of the gene for the second chain of the human interferon gamma receptor.

Q69YI7	NAIF1_HUMAN	Nuclear apoptosis-inducing factor 1	16378748	Overexpression of the novel human gene, nuclear apoptosis-inducing factor 1, induces apoptosis.

Q8W206	CSN6A_ARATH	COP9 signalosome complex subunit 6a	11701877	Molecular characterization of subunit 6 of the COP9 signalosome and its role in multifaceted developmental processes in Arabidopsis.

Q15067	ACOX1_HUMAN	Peroxisomal acyl-coenzyme A oxidase 1	7876265	Overexpression and characterization of the human peroxisomal acyl-CoA oxidase in insect cells.

Q9STY0	PX11B_ARATH	Peroxisomal membrane protein 11B	17220199	The PEROXIN11 protein family controls peroxisome proliferation in Arabidopsis.

Q96D09	GASP2_HUMAN	G-protein coupled receptor-associated sorting protein 2	15086532	Identification of a novel family of G protein-coupled receptor associated sorting proteins.

Q9W2B1	GR58B_DROME	Putative gustatory receptor 58b	10710312	Candidate taste receptors in Drosophila.

P17032	ZN37A_HUMAN	Zinc finger protein 37A	8464732	Duplicated KOX zinc finger gene clusters flank the centromere of human chromosome 10: evidence for a pericentric inversion during primate evolution.

Q91399	ID3A_XENLA	DNA-binding protein inhibitor ID-3-A	7619724	Id gene activity during Xenopus embryogenesis.

Q9Z1S7	OMD_RAT	Osteomodulin	10607915	Tissue distribution of a novel cell binding protein, osteoadherin, in the rat.

Q9Y265	RUVB1_HUMAN	RuvB-like 1	9843967	Pontin52, an interaction partner of beta-catenin, binds to the TATA box binding protein.

Q10474	LYS5_SCHPO	L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase	15546125	Posttranslational activation, site-directed mutation and phylogenetic analyses of the lysine biosynthesis enzymes alpha-aminoadipate reductase Lys1p (AAR) and the phosphopantetheinyl transferase Lys7p (PPTase) from Schizosaccharomyces pombe.

Q08162	RRP44_YEAST	Exosome complex exonuclease DIS3	9390555	The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases.

O59830	YCUA_SCHPO	Uncharacterized transcriptional regulatory protein C965.10	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q14242	SELPL_HUMAN	P-selectin glycoprotein ligand 1	7505206	Expression cloning of a functional glycoprotein ligand for P- selectin.

O95707	RPP29_HUMAN	Ribonuclease P protein subunit p29	10352175	hPop4: a new protein subunit of the human RNase MRP and RNase P ribonucleoprotein complexes.

P58334	KLF16_MOUSE	Krueppel-like factor 16	11390978	Dopamine receptor regulating factor, DRRF: a zinc finger transcription factor.

P20338	RAB4A_HUMAN	Ras-related protein Rab-4A	16034420	Structural basis of family-wide Rab GTPase recognition by rabenosyn- 5.

Q5TCQ9	MAGI3_HUMAN	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3	10748157	Interaction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI3, a novel membrane-associated guanylate kinase.

P24058	ARLY2_ANAPL	Argininosuccinate lyase	15320872	Structural studies of duck delta2 crystallin mutants provide insight into the role of Thr161 and the 280s loop in catalysis.

Q62009	POSTN_MOUSE	Periostin	7663166	Expression and characterization of murine osteoblast-specific factor 2 (OSF-2) in a baculovirus expression system.

P63104	1433Z_HUMAN	14-3-3 protein zeta/delta	19172738	Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein.

Q9PW35	VMACA_AGKAC	Zinc metalloproteinase acutolysin-A	9784374	Crystal structures of acutolysin A, a three-disulfide hemorrhagic zinc metalloproteinase from the snake venom of Agkistrodon acutus.

Q9C5P4	SUVH3_ARATH	Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH3	11691919	The Arabidopsis thaliana genome contains at least 29 active genes encoding SET domain proteins that can be assigned to four evolutionarily conserved classes.

P03372	ESR1_HUMAN	Estrogen receptor	15891768	Functional regulation of oestrogen receptor pathway by the dynein light chain 1.

Q8TCU5	NMD3A_HUMAN	Glutamate [NMDA] receptor subunit 3A	11880201	Cloning and expression of the human NMDA receptor subunit NR3A.

P47818	CCC1_YEAST	Protein CCC1	8866476	The role of the Saccharomyces cerevisiae CCC1 gene in the homeostasis of manganese ions.

Q9FY48	KEG_ARATH	E3 ubiquitin-protein ligase KEG	17194765	KEEP ON GOING, a RING E3 ligase essential for Arabidopsis growth and development, is involved in abscisic acid signaling.

O73689	ZIC1_XENLA	Zinc finger protein ZIC 1	9655809	Opl: a zinc finger protein that regulates neural determination and patterning in Xenopus.

P54681	RTOA_DICDI	Protein rtoA	15679845	Dictyostelium discoideum strains lacking the RtoA protein are defective for maturation of the Legionella pneumophila replication vacuole.

O75369	FLNB_HUMAN	Filamin-B	9651345	Human beta-filamin is a new protein that interacts with the cytoplasmic tail of glycoprotein Ibalpha.

Q6ZWQ0	SYNE2_MOUSE	Nesprin-2	18477613	Nesprin-2 Giant (NUANCE) maintains nuclear envelope architecture and composition in skin.

Q6P2E9	EDC4_HUMAN	Enhancer of mRNA-decapping protein 4	7520377	The immunoreactive region in a novel autoantigen contains a nuclear localization sequence.

Q9UBP9	GULP1_HUMAN	PTB domain-containing engulfment adapter protein 1	10574771	Human CED-6 encodes a functional homologue of the Caenorhabditis elegans engulfment protein CED-6.

P52712	CBPX_ORYSJ	Serine carboxypeptidase-like	7972496	Organ-specific and hormone-dependent expression of genes for serine carboxypeptidases during development and following germination of rice grains.

P80967	TOM5_YEAST	Mitochondrial import receptor subunit TOM5	9217162	Tom5 functionally links mitochondrial preprotein receptors to the general import pore.

P38880	MDM31_YEAST	Mitochondrial distribution and morphology protein 31	14562095	Global analysis of protein localization in budding yeast.

Q9ZUY3	AROD3_ARATH	Arogenate dehydratase 3, chloroplastic	19136569	Tyrosine and phenylalanine are synthesized within the plastids in Arabidopsis.

P17252	KPCA_HUMAN	Protein kinase C alpha type	12893243	Centaurin-alpha(1) associates with and is phosphorylated by isoforms of protein kinase C.

Q8IWU5	SULF2_HUMAN	Extracellular sulfatase Sulf-2	12368295	Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans.

O75182	SIN3B_HUMAN	Paired amphipathic helix protein Sin3b	12670868	Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell- proliferation factor HCF-1.

Q59X38	PESC_CANAL	Pescadillo homolog	19075239	The Candida albicans pescadillo homolog is required for normal hypha- to-yeast morphogenesis and yeast proliferation.

Q8BLA8	TRPA1_MOUSE	Transient receptor potential cation channel subfamily A member 1	16564016	TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents.

P47104	RAV1_YEAST	Regulator of V-ATPase in vacuolar membrane protein 1	11844802	The RAVE complex is essential for stable assembly of the yeast V- ATPase.

Q9BUL8	PDC10_HUMAN	Programmed cell death protein 10	20489202	Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity.

O14098	CTK1_SCHPO	CTD kinase subunit alpha	17502918	A cyclin-dependent kinase that promotes cytokinesis through modulating phosphorylation of the carboxy terminal domain of the RNA Pol II Rpb1p sub-unit.

P22392	NDKB_HUMAN	Nucleoside diphosphate kinase B	1851158	Nucleoside diphosphate kinase from human erythrocytes. Structural characterization of the two polypeptide chains responsible for heterogeneity of the hexameric enzyme.

P41911	GPD2_YEAST	Glycerol-3-phosphate dehydrogenase [NAD+] 2, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

O74346	MAP4_SCHPO	P cell-type agglutination protein map4	16857197	The fission yeast Map4 protein is a novel adhesin required for mating.

Q9NQS7	INCE_HUMAN	Inner centromere protein	9864353	INCENP centromere and spindle targeting: identification of essential conserved motifs and involvement of heterochromatin protein HP1.

Q61572	FOXC1_MOUSE	Forkhead box protein C1	9635428	The forkhead/winged helix gene Mf1 is disrupted in the pleiotropic mouse mutation congenital hydrocephalus.

Q33DR2	DPS1_MOUSE	Decaprenyl-diphosphate synthase subunit 1	16262699	Characterization of solanesyl and decaprenyl diphosphate synthases in mice and humans.

Q63634	NPY5R_RAT	Neuropeptide Y receptor type 5	8824284	Identification of a novel hypothalamic neuropeptide Y receptor associated with feeding behavior.

Q9BYG8	GSDMC_HUMAN	Gasdermin-C	11223543	Structure, expression and chromosome mapping of MLZE, a novel gene which is preferentially expressed in metastatic melanoma cells.

Q86X95	CIR1_HUMAN	Corepressor interacting with RBPJ 1	9874765	CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex.

Q9UMX0	UBQL1_HUMAN	Ubiquilin-1	11076969	Identification of ubiquilin, a novel presenilin interactor that increases presenilin protein accumulation.

P06400	RB_HUMAN	Retinoblastoma-associated protein	3657987	The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity.

P58295	SC6A5_RAT	Sodium- and chloride-dependent glycine transporter 2	8226790	Cloning and expression of a spinal cord- and brain-specific glycine transporter with novel structural features.

P31122	SOTB_ECOLI	Sugar efflux transporter	10438792	Escherichia coli gene ydeA encodes a major facilitator pump which exports L-arabinose and isopropyl-beta-D-thiogalactopyranoside.

Q38898	AKT2_ARATH	Potassium channel AKT2/3	12172027	Outer pore residues control the H(+) and K(+) sensitivity of the Arabidopsis potassium channel AKT3.

Q86UL8	MAGI2_HUMAN	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2	9647693	Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins.

P78504	JAG1_HUMAN	Protein jagged-1	8955070	An antisense oligonucleotide to the notch ligand Jagged enhances fibroblast growth factor-induced angiogenesis in vitro.

Q9V345	CSN4_DROME	COP9 signalosome complex subunit 4	10531038	The COP9 signalosome is essential for development of Drosophila melanogaster.

Q99496	RING2_HUMAN	E3 ubiquitin-protein ligase RING2	16714294	Structure of a Bmi-1-Ring1B polycomb group ubiquitin ligase complex.

Q50L41	PA24F_MOUSE	Cytosolic phospholipase A2 zeta	15866882	Identification of novel cytosolic phospholipase A(2)s, murine cPLA(2)delta, epsilon, and zeta, which form a gene cluster with cPLA(2)beta.

Q97ZX2	ALAXM_SULSO	Alanyl-tRNA editing protein AlaX-M	14663147	Trans-editing of mischarged tRNAs.

Q9NUW8	TYDP1_HUMAN	Tyrosyl-DNA phosphodiesterase 1	15811850	Substrate specificity of tyrosyl-DNA phosphodiesterase I (Tdp1).

P46778	RL21_HUMAN	60S ribosomal protein L21	7772601	Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs.

O08524	TECTB_MOUSE	Beta-tectorin	9079715	The mouse tectorins. Modular matrix proteins of the inner ear homologous to components of the sperm-egg adhesion system.

Q3T1J1	IF5A1_RAT	Eukaryotic translation initiation factor 5A-1	19006180	Involvement of eukaryotic translation initiation factor 5A (eIF5A) in skeletal muscle stem cell differentiation.

P28240	ACEA_YEAST	Isocitrate lyase	1551398	The ICL1 gene from Saccharomyces cerevisiae.

P40107	GMT1_YEAST	GDP-mannose transporter 1	9395539	The VRG4 gene is required for GDP-mannose transport into the lumen of the Golgi in the yeast, Saccharomyces cerevisiae.

P09234	RU1C_HUMAN	U1 small nuclear ribonucleoprotein C	15312772	The structure and biochemical properties of the human spliceosomal protein U1C.

Q9W740	NOGG2_DANRE	Noggin-2	10491267	Three different noggin genes antagonize the activity of bone morphogenetic proteins in the zebrafish embryo.

Q9UQD0	SCN8A_HUMAN	Sodium channel protein type 8 subunit alpha	9828131	Exon organization, coding sequence, physical mapping, and polymorphic intragenic markers for the human neuronal sodium channel gene SCN8A.

Q14722	KCAB1_HUMAN	Voltage-gated potassium channel subunit beta-1	7499366	A novel K+ channel beta-subunit (hKv beta 1.3) is produced via alternative mRNA splicing.

P10124	SRGN_HUMAN	Serglycin	11911826	Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation.

P63279	UBC9_HUMAN	SUMO-conjugating enzyme UBC9	19744555	Sumoylation of forkhead L2 by Ubc9 is required for its activity as a transcriptional repressor of the Steroidogenic Acute Regulatory gene.

P93831	CLF_ARATH	Histone-lysine N-methyltransferase CLF	11063708	Genetic analysis of incurvata mutants reveals three independent genetic operations at work in Arabidopsis leaf morphogenesis.

Q12339	UTP23_YEAST	rRNA-processing protein UTP23	14562095	Global analysis of protein localization in budding yeast.

Q8GW72	FUCO1_ARATH	Alpha-L-fucosidase 1	16516937	Molecular cloning and characterization of a plant alpha1,3/4- fucosidase based on sequence tags from almond fucosidase I.

O14185	STG1_SCHPO	Transgelin	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P21574	YBX2A_XENLA	Y-box-binding protein 2-A	1902800	Purification of two thermostable components of messenger ribonucleoprotein particles (mRNPs) from Xenopus laevis oocytes, belonging to a novel class of RNA-binding proteins.

P46687	GASA3_ARATH	Gibberellin-regulated protein 3	7727751	GASA, a gibberellin-regulated gene family from Arabidopsis thaliana related to the tomato GAST1 gene.

P22189	ATC3_SCHPO	Calcium-transporting ATPase 3	2145281	Calcium homeostasis and transport are affected by disruption of cta3, a novel gene encoding Ca2(+)-ATPase in Schizosaccharomyces pombe.

O60930	RNH1_HUMAN	Ribonuclease H1	9799596	Cloning, expression, and mapping of ribonucleases H of human and mouse related to bacterial RNase HI.

Q5ZPR3	CD276_HUMAN	CD276 antigen	11224528	B7-H3: a costimulatory molecule for T cell activation and IFN-gamma production.

P35800	DPY10_CAEEL	Cuticle collagen dpy-10	8241567	Molecular and genetic analyses of the Caenorhabditis elegans dpy-2 and dpy-10 collagen genes: a variety of molecular alterations affect organismal morphology.

Q42400	AAP1_ARATH	Amino acid permease 1	8356039	Cloning a plant amino acid transporter by functional complementation of a yeast amino acid transport mutant.

Q9Z1S8	GAB2_MOUSE	GRB2-associated-binding protein 2	16456001	Scaffolding adapter Grb2-associated binder 2 requires Syk to transmit signals from FcepsilonRI.

Q91ZT5	FGD4_MOUSE	FYVE, RhoGEF and PH domain-containing protein 4	11527409	Identification of splicing variants of Frabin with partly different functions and tissue distribution.

Q9M0S5	ISOA3_ARATH	Isoamylase 3, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

Q6NKX1	PROD2_ARATH	Proline dehydrogenase 2, mitochondrial	20403182	Non-redundant functions of two proline dehydrogenase isoforms in Arabidopsis.

P12868	PEP5_YEAST	Vacuolar membrane protein PEP5	16601699	Purification of active HOPS complex reveals its affinities for phosphoinositides and the SNARE Vam7p.

Q62753	STXB2_RAT	Syntaxin-binding protein 2	7768895	A novel ubiquitous form of Munc-18 interacts with multiple syntaxins. Use of the yeast two-hybrid system to study interactions between proteins involved in membrane traffic.

O00522	KRIT1_HUMAN	Krev interaction trapped protein 1	9285558	Association of Krev-1/rap1a with Krit1, a novel ankyrin repeat- containing protein encoded by a gene mapping to 7q21-22.

Q5XJQ7	OSR1_DANRE	Protein odd-skipped-related 1	17011543	Odd-skipped genes encode repressors that control kidney development.

P41596	DOPR1_DROME	Dopamine receptor 1	7953290	Primary structure and functional characterization of a Drosophila dopamine receptor with high homology to human D1/5 receptors.

Q12972	PP1R8_HUMAN	Nuclear inhibitor of protein phosphatase 1	7499293	Molecular cloning of NIPP-1, a nuclear inhibitor of protein phosphatase-1, reveals homology with polypeptides involved in RNA processing.

Q54R82	MKKA_DICDI	Mitogen-activated protein kinase kinase kinase A	9832508	A novel, putative MEK kinase controls developmental timing and spatial patterning in Dictyostelium and is regulated by ubiquitin- mediated protein degradation.

Q9FJK3	AGL80_ARATH	Agamous-like MADS-box protein AGL80	18713950	The MADS domain protein DIANA acts together with AGAMOUS-LIKE80 to specify the central cell in Arabidopsis ovules.

Q63615	VP33A_RAT	Vacuolar protein sorting-associated protein 33A	11382755	Molecular characterization of mammalian homologues of class c Vps proteins that interact with syntaxin-7.

Q6VH22	IF172_MOUSE	Intraflagellar transport protein 172 homolog	14603322	Hedgehog signalling in the mouse requires intraflagellar transport proteins.

P08253	MMP2_HUMAN	72 kDa type IV collagenase	2834383	H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen.

Q9WTY1	PDCD7_MOUSE	Programmed cell death protein 7	10037816	Characterization of a novel mouse cDNA, ES18, involved in apoptotic cell death of T-cells.

O80339	ERF82_ARATH	Ethylene-responsive transcription factor 3	16429262	AtSAP18, an orthologue of human SAP18, is involved in the regulation of salt stress and mediates transcriptional repression in Arabidopsis.

Q9LDR4	ERG24_ARATH	Delta(14)-sterol reductase	10859166	FACKEL is a sterol C-14 reductase required for organized cell division and expansion in Arabidopsis embryogenesis.

Q9UHF0	TKNK_HUMAN	Tachykinin-3	10866201	Excessive placental secretion of neurokinin B during the third trimester causes pre-eclampsia.

P40348	RFC2_YEAST	Replication factor C subunit 2	12912927	Elg1 forms an alternative RFC complex important for DNA replication and genome integrity.

Q99942	RNF5_HUMAN	E3 ubiquitin-protein ligase RNF5	19285439	The ubiquitin ligase RNF5 regulates antiviral responses by mediating degradation of the adaptor protein MITA.

P48023	TNFL6_HUMAN	Tumor necrosis factor ligand superfamily member 6	8787672	Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease.

Q9BZC1	CELF4_HUMAN	CUGBP Elav-like family member 4	11158314	The CELF family of RNA binding proteins is implicated in cell- specific and developmentally regulated alternative splicing.

P34278	KNL1_CAEEL	Kinetochore null protein 1	18765790	A new mechanism controlling kinetochore-microtubule interactions revealed by comparison of two dynein-targeting components: SPDL-1 and the Rod/Zwilch/Zw10 complex.

Q99MR6	SRRT_MOUSE	Serrate RNA effector molecule homolog	19632182	Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation.

Q9UTC5	YIDE_SCHPO	Putative uridine kinase C227.14	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9HAV5	TNR27_HUMAN	Tumor necrosis factor receptor superfamily member 27	12270937	Role of TRAF3 and -6 in the activation of the NF-kappa B and JNK pathways by X-linked ectodermal dysplasia receptor.

B0F9L7	GOGC2_ARATH	Golgin candidate 2	18182439	Localization and domain characterization of Arabidopsis golgin candidates.

Q96FV9	THOC1_HUMAN	THO complex subunit 1	18974867	Recruitment of the complete hTREX complex is required for Kaposi's sarcoma-associated herpesvirus intronless mRNA nuclear export and virus replication.

Q5CCK4	VAL2_ARATH	B3 domain-containing transcription repressor VAL2	17267611	Two B3 domain transcriptional repressors prevent sugar-inducible expression of seed maturation genes in Arabidopsis seedlings.

O15524	SOCS1_HUMAN	Suppressor of cytokine signaling 1	9202125	A family of cytokine-inducible inhibitors of signaling.

Q9NY15	STAB1_HUMAN	Stabilin-1	12077138	FEEL-1, a novel scavenger receptor with in vitro bacteria-binding and angiogenesis-modulating activities.

Q90Z05	VNG2B_XENLA	Vang-like protein 2-B	12074560	The planar cell polarity gene strabismus regulates convergence and extension and neural fold closure in Xenopus.

Q5S003	SPG17_MOUSE	Sperm-associated antigen 17	15827353	Dissecting the axoneme interactome: the mammalian orthologue of Chlamydomonas PF6 interacts with sperm-associated antigen 6, the mammalian orthologue of Chlamydomonas PF16.

Q8VYR5	PP351_ARATH	Pentatricopeptide repeat-containing protein At4g35850, mitochondrial	11743115	Analysis of the Arabidopsis mitochondrial proteome.

P0AEX9	MALE_ECOLI	Maltose-binding periplasmic protein	2002054	The 2.3-A resolution structure of the maltose-or maltodextrin-binding protein, a primary receptor of bacterial active transport and chemotaxis.

P32905	RSSA1_YEAST	40S ribosomal protein S0-A	9973221	Yeast proteins related to the p40/laminin receptor precursor are required for 20S ribosomal RNA processing and the maturation of 40S ribosomal subunits.

Q16625	OCLN_HUMAN	Occludin	8601611	Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues.

O95149	SPN1_HUMAN	Snurportin-1	9670026	Snurportin1, an m3G-cap-specific nuclear import receptor with a novel domain structure.

P31721	C1QB_RAT	Complement C1q subcomponent subunit B	7594503	Follicular dendritic cells, interdigitating cells, and cells of the monocyte-macrophage lineage are the C1q-producing sources in the spleen. Identification of specific cell types by in situ hybridization and immunohistochemical analysis.

P0AEF4	DPIA_ECOLI	Transcriptional regulatory protein DpiA	19202292	Characterization of CitA-CitB signal transduction activating genes involved in anaerobic citrate catabolism in Escherichia coli.

O35181	NRG3_MOUSE	Pro-neuregulin-3, membrane-bound isoform	9275162	Neuregulin-3 (NRG3): a novel neural tissue-enriched protein that binds and activates ErbB4.

O43896	KIF1C_HUMAN	Kinesin-like protein KIF1C	9685376	Characterization of KIF1C, a new kinesin-like protein involved in vesicle transport from the Golgi apparatus to the endoplasmic reticulum.

Q13042	CDC16_HUMAN	Cell division cycle protein 16 homolog	18485873	Mechanism of ubiquitin-chain formation by the human anaphase- promoting complex.

Q6DE08	AUKBA_XENLA	Serine/threonine-protein kinase 12-A	10996078	INCENP binds the Aurora-related kinase AIRK2 and is required to target it to chromosomes, the central spindle and cleavage furrow.

Q9FT81	TT8_ARATH	Transcription factor TT8	15361138	Comprehensive identification of Arabidopsis thaliana MYB transcription factors interacting with R/B-like BHLH proteins.

Q19345	NHR25_CAEEL	Nuclear hormone receptor family member nhr-25	10772806	nhr-25, the Caenorhabditis elegans ortholog of ftz-f1, is required for epidermal and somatic gonad development.

P32214	CALCR_RAT	Calcitonin receptor	8395656	Identification of brain isoforms of the rat calcitonin receptor.

Q9XUB2	MEX5_CAEEL	Zinc finger protein mex-5	10882103	MEX-5 and MEX-6 function to establish soma/germline asymmetry in early C. elegans embryos.

Q10303	ALP21_SCHPO	Cell polarity protein alp21	10341216	Sto1p, a fission yeast protein similar to tubulin folding cofactor E, plays an essential role in mitotic microtubule assembly.

P20965	PABPA_XENLA	Polyadenylate-binding protein 1-A	1280105	Purification and characterization of recombinant Xenopus poly(A)(+)- binding protein expressed in a baculovirus system.

Q8TD30	ALAT2_HUMAN	Alanine aminotransferase 2	11863375	cDNA cloning, genomic structure, chromosomal mapping, and functional expression of a novel human alanine aminotransferase.

Q9ERC8	DSCAM_MOUSE	Down syndrome cell adhesion molecule homolog	18216855	Neurite arborization and mosaic spacing in the mouse retina require DSCAM.

O22229	TRXB3_ARATH	NADPH-dependent thioredoxin reductase 3	18625226	NADPH-dependent thioredoxin reductase and 2-Cys peroxiredoxins are needed for the protection of Mg-protoporphyrin monomethyl ester cyclase.

Q04225	RRB1_YEAST	Ribosome assembly protein RRB1	11728313	A yeast homolog of chromatin assembly factor 1 is involved in early ribosome assembly.

Q9PTK2	FOXE4_XENLA	Forkhead box protein E4	10529427	A novel fork head gene mediates early steps during Xenopus lens formation.

P32561	RPD3_YEAST	Histone deacetylase RPD3	9234741	A large protein complex containing the yeast Sin3p and Rpd3p transcriptional regulators.

Q39228	STP4_ARATH	Sugar transport protein 4	8989877	The sink-specific and stress-regulated Arabidopsis STP4 gene: enhanced expression of a gene encoding a monosaccharide transporter by wounding, elicitors, and pathogen challenge.

P04035	HMDH_HUMAN	3-hydroxy-3-methylglutaryl-coenzyme A reductase	2991281	Human 3-hydroxy-3-methylglutaryl coenzyme A reductase. Conserved domains responsible for catalytic activity and sterol-regulated degradation.

Q9ZVN2	Y1457_ARATH	Acyltransferase-like protein At1g54570, chloroplastic	16461379	Protein profiling of plastoglobules in chloroplasts and chromoplasts. A surprising site for differential accumulation of metabolic enzymes.

P53829	CAF40_YEAST	Protein CAF40	11733989	Purification and characterization of the 1.0 MDa CCR4-NOT complex identifies two novel components of the complex.

Q86JF2	LVSB_DICDI	BEACH domain-containing protein lvsB	11854420	Dictyostelium LvsB mutants model the lysosomal defects associated with Chediak-Higashi syndrome.

P60602	ROMO1_HUMAN	Reactive oxygen species modulator 1	18313394	A critical role for Romo1-derived ROS in cell proliferation.

Q9VH48	CARM1_DROME	Probable histone-arginine methyltransferase CARMER	14705965	Characterization of the Drosophila protein arginine methyltransferases DART1 and DART4.

P37610	TAUD_ECOLI	Alpha-ketoglutarate-dependent taurine dioxygenase	11955067	X-ray crystal structure of Escherichia coli taurine/alpha- ketoglutarate dioxygenase complexed to ferrous iron and substrates.

Q9H9S0	NANOG_HUMAN	Homeobox protein NANOG	15108323	Identification, cloning and expression analysis of the pluripotency promoting Nanog genes in mouse and human.

P36623	PMGY_SCHPO	Phosphoglycerate mutase	8110200	The amino acid sequence of the small monomeric phosphoglycerate mutase from the fission yeast Schizosaccharomyces pombe.

P59025	RTP1_HUMAN	Receptor-transporting protein 1	15550249	RTP family members induce functional expression of mammalian odorant receptors.

P21728	DRD1_HUMAN	D(1A) dopamine receptor	2144334	Molecular cloning and expression of the gene for a human D1 dopamine receptor.

P82600	PERC_AEDAE	Chorion peroxidase	8900599	Involvement of peroxidase in chorion hardening in Aedes aegypti.

Q9NQC3	RTN4_HUMAN	Reticulon-4	11126360	A novel protein, RTN-XS, interacts with both Bcl-XL and Bcl-2 on endoplasmic reticulum and reduces their anti-apoptotic activity.

Q9BWE0	REPI1_HUMAN	Replication initiator 1	10606657	The dhfr oribeta-binding protein RIP60 contains 15 zinc fingers: DNA binding and looping by the central three fingers and an associated proline-rich region.

O88712	CTBP1_MOUSE	C-terminal-binding protein 1	14736873	Characterization of four autonomous repression domains in the corepressor receptor interacting protein 140.

P42261	GRIA1_HUMAN	Glutamate receptor 1	1320959	The human glutamate receptor cDNA GluR1: cloning, sequencing, expression and localization to chromosome 5.

Q02248	CTNB1_MOUSE	Catenin beta-1	11590244	AlphaT-catenin: a novel tissue-specific beta-catenin-binding protein mediating strong cell-cell adhesion.

P0C960	EMTA_ECOLI	Endo-type membrane-bound lytic murein transglycosylase A	9642199	Membrane-bound lytic endotransglycosylase in Escherichia coli.

O43511	S26A4_HUMAN	Pendrin	9398842	Pendred syndrome is caused by mutations in a putative sulphate transporter gene (PDS).

P38986	ASPG1_YEAST	L-asparaginase 1	8026756	The ASP1 gene of Saccharomyces cerevisiae, encoding the intracellular isozyme of L-asparaginase.

O15392	BIRC5_HUMAN	Baculoviral IAP repeat-containing protein 5	11084331	Survivin and the inner centromere protein INCENP show similar cell- cycle localization and gene knockout phenotype.

Q8L4R0	TGD1_ARATH	Protein TRIGALACTOSYLDIACYLGLYCEROL 1, chloroplastic	16199613	Mutation of the TGD1 chloroplast envelope protein affects phosphatidate metabolism in Arabidopsis.

Q8MML5	PAXB_DICDI	Paxillin-B	16155255	Paxillin is required for cell-substrate adhesion, cell sorting and slug migration during Dictyostelium development.

Q65Z40	WAPL_MOUSE	Wings apart-like protein homolog	15620708	A dioxin sensitive gene, mammalian WAPL, is implicated in spermatogenesis.

Q96B01	R51A1_HUMAN	RAD51-associated protein 1	9396801	A novel nucleic acid-binding protein that interacts with human rad51 recombinase.

Q9HCN3	TMM8A_HUMAN	Transmembrane protein 8A	11006113	Molecular cloning and chromosomal mapping of a novel five-span transmembrane protein gene, M83.

Q13123	RED_HUMAN	Protein Red	7970704	A new cytokine (IK) down-regulating HLA class II: monoclonal antibodies, cloning and chromosome localization.

P62330	ARF6_HUMAN	ADP-ribosylation factor 6	1993656	Molecular identification of ADP-ribosylation factor mRNAs and their expression in mammalian cells.

P39875	EXO1_YEAST	Exodeoxyribonuclease 1	9207118	Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2.

Q9H339	O51B5_HUMAN	Olfactory receptor 51B5	11121057	Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.

P38353	SSH1_YEAST	Sec sixty-one protein homolog	11702951	Ssh1p determines the translocation and dislocation capacities of the yeast endoplasmic reticulum.

Q02872	YP108_YEAST	Uncharacterized protein YPL108W	14562095	Global analysis of protein localization in budding yeast.

P83705	HLOA_HALAU	Halocidin subunit A	12067731	Halocidin: a new antimicrobial peptide from hemocytes of the solitary tunicate, Halocynthia aurantium.

P38888	MNL1_YEAST	ER degradation-enhancing alpha-mannosidase-like protein 1	11375935	Htm1p, a mannosidase-like protein, is involved in glycoprotein degradation in yeast.

Q08422	YO052_YEAST	AN1-type zinc finger protein YOR052C	14562095	Global analysis of protein localization in budding yeast.

O14286	ATM1_SCHPO	Iron-sulfur clusters transporter atm1, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P29197	CH60A_ARATH	Chaperonin CPN60, mitochondrial	1349837	cDNA clones encoding Arabidopsis thaliana and Zea mays mitochondrial chaperonin HSP60 and gene expression during seed germination and heat shock.

Q9P7J8	GAD8_SCHPO	Serine/threonine-protein kinase gad8	12805221	Schizosaccharomyces pombe AGC family kinase Gad8p forms a conserved signaling module with TOR and PDK1-like kinases.

Q53FA7	QORX_HUMAN	Quinone oxidoreductase PIG3	19349281	Three-dimensional structure and enzymatic function of proapoptotic human p53-inducible quinone oxidoreductase PIG3.

P25446	TNR6_MOUSE	Tumor necrosis factor receptor superfamily member 6	11034606	FIST/HIPK3: a Fas/FADD-interacting serine/threonine kinase that induces FADD phosphorylation and inhibits Fas-mediated Jun NH2- terminal kinase activation.

P38348	HSM3_YEAST	DNA mismatch repair protein HSM3	19217412	Hsm3/S5b participates in the assembly pathway of the 19S regulatory particle of the proteasome.

Q08231	THP1_YEAST	Nuclear mRNA export protein THP1	12206772	Genome-wide nuclear morphology screen identifies novel genes involved in nuclear architecture and gene-silencing in Saccharomyces cerevisiae.

P52850	NDST2_MOUSE	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2	10466726	Heparin is essential for the storage of specific granule proteases in mast cells.

Q99MQ3	PINK1_MOUSE	Serine/threonine-protein kinase PINK1, mitochondrial	14607334	BRPK, a novel protein kinase showing increased expression in mouse cancer cell lines with higher metastatic potential.

Q9UW18	TOXG_COCCA	Alanine racemase TOXG	10671527	A eukaryotic alanine racemase gene involved in cyclic peptide biosynthesis.

P97343	UHMK1_MOUSE	Serine/threonine-protein kinase Kist	7724523	Stathmin interaction with a putative kinase and coiled-coil-forming protein domains.

Q7T103	P5F11_XENLA	POU domain, class 5, transcription factor 1.1	17541407	POU-V factors antagonize maternal VegT activity and beta-Catenin signaling in Xenopus embryos.

Q04724	TLE1_HUMAN	Transducin-like enhancer protein 1	9751710	Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors.

P09021	HXA5_MOUSE	Homeobox protein Hox-A5	8635464	Functional dissection of the mouse Hox-a5 gene.

Q552M5	GEFY_DICDI	Ras guanine nucleotide exchange factor Y	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

Q08215	PEX15_YEAST	Peroxisomal membrane protein PEX15	12808025	Pex15p of Saccharomyces cerevisiae provides a molecular basis for recruitment of the AAA peroxin Pex6p to peroxisomal membranes.

O88506	STK39_RAT	STE20/SPS1-related proline-alanine-rich protein kinase	10980603	SPAK, a STE20/SPS1-related kinase that activates the p38 pathway.

Q8TB45	DEPD6_HUMAN	DEP domain-containing mTOR-interacting protein	19446321	DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival.

Q99MR0	ACL6B_MOUSE	Actin-like protein 6B	17640523	An essential switch in subunit composition of a chromatin remodeling complex during neural development.

P80667	PEX13_YEAST	Peroxisomal membrane protein PAS20	8858167	Identification of Pex13p a peroxisomal membrane receptor for the PTS1 recognition factor.

Q60793	KLF4_MOUSE	Krueppel-like factor 4	8702718	Identification and characterization of a gene encoding a gut-enriched Kruppel-like factor expressed during growth arrest.

P38890	SET5_YEAST	Putative protein lysine methyltransferase SET5	14562095	Global analysis of protein localization in budding yeast.

Q9UTR1	MMS19_SCHPO	DNA repair/transcription protein mms19	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O95859	TSN12_HUMAN	Tetraspanin-12	10719184	Sequence and expression of seven new tetraspans.

Q9V5M3	LOLA6_DROME	Longitudinals lacking protein, isoforms N/O/W/X/Y	8050351	Lola encodes a putative transcription factor required for axon growth and guidance in Drosophila.

O04373	ILL4_ARATH	IAA-amino acid hydrolase ILR1-like 4	10072397	IAR3 encodes an auxin conjugate hydrolase from Arabidopsis.

P26798	INO2_YEAST	Protein INO2	8125958	Functional characterization of the INO2 gene of Saccharomyces cerevisiae. A positive regulator of phospholipid biosynthesis.

P41224	TEF_RAT	Thyrotroph embryonic factor	1916262	TEF, a transcription factor expressed specifically in the anterior pituitary during embryogenesis, defines a new class of leucine zipper proteins.

Q9SZJ5	GLYM_ARATH	Serine hydroxymethyltransferase, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q5EXX3	ZBT38_RAT	Zinc finger and BTB domain-containing protein 38	15713629	ZENON, a novel POZ Kruppel-like DNA binding protein associated with differentiation and/or survival of late postmitotic neurons.

Q55GS3	DICB_DICDI	Discoidin-inducing complex subunit B	15947191	A cysteine-rich extracellular protein containing a PA14 domain mediates quorum sensing in Dictyostelium discoideum.

P50527	STE20_SCHPO	Serine/threonine-protein kinase shk1/pak1	7597098	Shk1, a homolog of the Saccharomyces cerevisiae Ste20 and mammalian p65PAK protein kinases, is a component of a Ras/Cdc42 signaling module in the fission yeast Schizosaccharomyces pombe.

O74957	AGO1_SCHPO	Protein argonaute	12733640	RNA interference is required for normal centromere function in fission yeast.

Q09327	MGAT3_HUMAN	Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	8370666	cDNA cloning, expression, and chromosomal localization of human N- acetylglucosaminyltransferase III (GnT-III).

O97148	MTH_DROME	G-protein coupled receptor Mth	15133470	The endogenous ligand Stunted of the GPCR Methuselah extends lifespan in Drosophila.

P40489	XBP1_YEAST	Transcriptional repressor XBP1	9343412	Xbp1, a stress-induced transcriptional repressor of the Saccharomyces cerevisiae Swi4/Mbp1 family.

Q8W4M7	ERCC2_ARATH	DNA repair helicase UVH6	12857822	Arabidopsis UVH6, a homolog of human XPD and yeast RAD3 DNA repair genes, functions in DNA repair and is essential for plant growth.

O15743	SPNA_DICDI	Protein spalten	9585512	Spalten, a protein containing Galpha-protein-like and PP2C domains, is essential for cell-type differentiation in Dictyostelium.

P32497	EIF3C_YEAST	Eukaryotic translation initiation factor 3 subunit C	9722586	Nip1p associates with 40 S ribosomes and the Prt1p subunit of eukaryotic initiation factor 3 and is required for efficient translation initiation.

Q16629	SRSF7_HUMAN	Serine/arginine-rich splicing factor 7	8013463	Characterization and cloning of the human splicing factor 9G8: a novel 35 kDa factor of the serine/arginine protein family.

P50171	DHB8_MOUSE	Estradiol 17-beta-dehydrogenase 8	9712896	Characterization of Ke 6, a new 17beta-hydroxysteroid dehydrogenase, and its expression in gonadal tissues.

P53256	RRP46_YEAST	Exosome complex component RRP46	10465791	The yeast exosome and human PM-Scl are related complexes of 3'-->5' exonucleases.

Q12151	UPC2_YEAST	Sterol uptake control protein 2	9696767	A mutation in a purported regulatory gene affects control of sterol uptake in Saccharomyces cerevisiae.

Q9LZ03	TOP6A_ARATH	DNA topoisomerase 6 subunit A	17951446	MIDGET unravels functions of the Arabidopsis topoisomerase VI complex in DNA endoreduplication, chromatin condensation, and transcriptional silencing.

Q12505	SKS1_YEAST	Serine/threonine-protein kinase SKS1	8948096	The SKS1 protein kinase is a multicopy suppressor of the snf3 mutation of Saccharomyces cerevisiae.

Q9H081	MIS12_HUMAN	Protein MIS12 homolog	15502821	A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1.

P23585	HXT2_YEAST	High-affinity glucose transporter HXT2	2233722	The HXT2 gene of Saccharomyces cerevisiae is required for high- affinity glucose transport.

Q08752	PPID_HUMAN	Peptidyl-prolyl cis-trans isomerase D	8812478	The structure and complete nucleotide sequence of the human cyclophilin 40 (PPID) gene.

P34288	PAC1_CAEEL	GTPase-activating protein pac-1	18583611	Polarization of the C. elegans embryo by RhoGAP-mediated exclusion of PAR-6 from cell contacts.

Q9Y2P7	ZN256_HUMAN	Zinc finger protein 256	10585455	Molecular cloning of six novel Kruppel-like zinc finger genes from hematopoietic cells and identification of a novel transregulatory domain KRNB.

P49747	COMP_HUMAN	Cartilage oligomeric matrix protein	12225811	Matrix-matrix interaction of cartilage oligomeric matrix protein and fibronectin.

Q96RT1	LAP2_HUMAN	Protein LAP2	10878805	ERBIN: a basolateral PDZ protein that interacts with the mammalian ERBB2/HER2 receptor.

P38880	MDM31_YEAST	Mitochondrial distribution and morphology protein 31	11907266	Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae.

P15649	HSL27_DICDI	HssA/B-like protein 27	2161991	Developmental regulation of cell-type-enriched mRNAs in Dictyostelium discoideum.

P13796	PLSL_HUMAN	Plastin-2	17294403	Costimulation induced phosphorylation of L-plastin facilitates surface transport of the T cell activation molecules CD69 and CD25.

P56399	UBP5_MOUSE	Ubiquitin carboxyl-terminal hydrolase 5	19156909	Characterization and potential function of a novel pre-implantation embryo-specific RING finger protein: TRIML1.

Q43385	DOF37_ARATH	Dof zinc finger protein DOF3.7	11842145	Inactivation of the phloem-specific Dof zinc finger gene DAG1 affects response to light and integrity of the testa of Arabidopsis seeds.

Q9FIJ0	RBOHD_ARATH	Respiratory burst oxidase homolog protein D	15608336	Cytosolic ascorbate peroxidase 1 is a central component of the reactive oxygen gene network of Arabidopsis.

Q93009	UBP7_HUMAN	Ubiquitin carboxyl-terminal hydrolase 7	9130697	ERRATUM
Q96SD1	DCR1C_HUMAN	Protein artemis	11955432	Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination.

Q8TEQ6	GEMI5_HUMAN	Gem-associated protein 5	16857593	The Gemin5 protein of the SMN complex identifies snRNAs.

Q148R9	R9BP_MOUSE	Regulator of G-protein signaling 9-binding protein	14625292	Absence of the RGS9.Gbeta5 GTPase-activating complex in photoreceptors of the R9AP knockout mouse.

Q8BZF2	NIPA4_MOUSE	Magnesium transporter NIPA4	18667602	Functional characterization of NIPA2, a selective Mg2+ transporter.

Q8VCW2	K1C25_MOUSE	Keratin, type I cytoskeletal 25	17920809	Mutations in the helix termination motif of mouse type I IRS keratin genes impair the assembly of keratin intermediate filament.

P35282	RAB21_MOUSE	Ras-related protein Rab-21	16754960	Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins.

Q9QXP7	C1QT1_MOUSE	Complement C1q tumor necrosis factor-related protein 1	15231994	A family of Acrp30/adiponectin structural and functional paralogs.

P20226	TBP_HUMAN	TATA-box-binding protein	10391676	Exon 4-encoded acidic domain in the epithelium-restricted Ets factor, ESX, confers potent transactivating capacity and binds to TATA-binding protein (TBP).

Q9D2A5	CR3L4_MOUSE	Cyclic AMP-responsive element-binding protein 3-like protein 4	11956138	Atce1: a novel mouse cyclic adenosine 3',5'-monophosphate-responsive element-binding protein-like gene exclusively expressed in postmeiotic spermatids.

Q9NUW8	TYDP1_HUMAN	Tyrosyl-DNA phosphodiesterase 1	17948061	Spinocerebellar ataxia with axonal neuropathy: consequence of a Tdp1 recessive neomorphic mutation?

O14599	VCY2_HUMAN	Testis-specific basic protein Y 2	9381176	Functional coherence of the human Y chromosome.

Q9Y4K3	TRAF6_HUMAN	TNF receptor-associated factor 6	14982987	Toll-like receptor 3-mediated activation of NF-kappaB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN- beta.

P16232	DHI1_RAT	Corticosteroid 11-beta-dehydrogenase isozyme 1	12460758	Purification of full-length recombinant human and rat type 1 11beta- hydroxysteroid dehydrogenases with retained oxidoreductase activities.

P51787	KCNQ1_HUMAN	Potassium voltage-gated channel subfamily KQT member 1	8900283	Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel.

P84682	SC39_TITCA	Toxin Tc39	15025998	Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

Q9P2T0	THEG_HUMAN	Testicular haploid expressed gene protein	10747865	Insertional mutation of the murine kisimo locus caused a defect in spermatogenesis.

O75306	NDUS2_HUMAN	NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial	9585441	Mapping to 1q23 of the human gene (NDUFS2) encoding the 49-kDa subunit of the mitochondrial respiratory complex I and immunodetection of the mature protein in mitochondria.

P48025	KSYK_MOUSE	Tyrosine-protein kinase SYK	7477352	Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk.

Q9HDZ8	YKP6_SCHPO	Uncharacterized protein C589.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Y2K6	UBP20_HUMAN	Ubiquitin carboxyl-terminal hydrolase 20	19424180	The deubiquitinases USP33 and USP20 coordinate beta2 adrenergic receptor recycling and resensitization.

Q9FKM5	XRCC3_ARATH	DNA repair protein XRCC3 homolog	14726957	The Arabidopsis homologue of Xrcc3 plays an essential role in meiosis.

P05371	CLUS_RAT	Clusterin	7680346	Genomic organization and expression of the rat TRPM-2 (clusterin) gene, a gene implicated in apoptosis.

Q9M2U1	DOF36_ARATH	Dof zinc finger protein DOF3.6	10758484	Characterization of salicylic acid-responsive, Arabidopsis Dof domain proteins: overexpression of OBP3 leads to growth defects.

Q9UBF6	RBX2_HUMAN	RING-box protein 2	10082581	SAG, a novel zinc RING finger protein that protects cells from apoptosis induced by redox agents.

P84919	TXC4_BUNCI	Neurotoxin BcIV	17015047	BcIV, a new paralyzing peptide obtained from the venom of the sea anemone Bunodosoma caissarum. A comparison with the Na(+) channel toxin BcIII.

P53705	BUD4_CANAL	Bud site selection protein BUD4	10444345	Systemic infection following intravenous inoculation of mice with Candida albicans int1 mutant strains.

P49959	MRE11_HUMAN	Double-strand break repair protein MRE11A	8530104	Isolation and characterization of the human MRE11 homologue.

Q21227	APR1_CAEEL	Adenomatous polyposis coli protein-related protein 1	10766743	The Caenorhabditis elegans APC-related gene apr-1 is required for epithelial cell migration and Hox gene expression.

P32500	NDC1_YEAST	Nucleoporin NDC1	10684247	The yeast nuclear pore complex: composition, architecture, and transport mechanism.

Q0WQF7	OPD21_ARATH	Dihydrolipoyllysine-residue acetyltransferase component 1 of pyruvate dehydrogenase complex, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

O95229	ZWINT_HUMAN	ZW10 interactor	15824131	ZW10 links mitotic checkpoint signaling to the structural kinetochore.

Q18212	UAP56_CAEEL	Spliceosome RNA helicase BAT1 homolog	12810918	UAP56 levels affect viability and mRNA export in Caenorhabditis elegans.

Q29980	MICB_HUMAN	MHC class I polypeptide-related sequence B	12782710	Human cytomegalovirus glycoprotein UL16 causes intracellular sequestration of NKG2D ligands, protecting against natural killer cell cytotoxicity.

Q16626	MEA1_HUMAN	Male-enhanced antigen 1	2813404	Male-enhanced antigen gene is phylogenetically conserved and expressed at late stages of spermatogenesis.

Q96P20	NALP3_HUMAN	NACHT, LRR and PYD domains-containing protein 3	14662828	CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties.

Q9FVN0	AMT13_SOLLC	Ammonium transporter 1 member 3	10743657	Differential regulation of three functional ammonium transporter genes by nitrogen in root hairs and by light in leaves of tomato.

Q04004	PLP1_YEAST	Phosducin-like protein 1	10749875	Functional analysis of Plp1 and Plp2, two homologues of phosducin in yeast.

Q07326	PIGF_HUMAN	Phosphatidylinositol-glycan biosynthesis class F protein	8463218	Cloning of a human gene, PIG-F, a component of glycosylphosphatidylinositol anchor biosynthesis, by a novel expression cloning strategy.

P30656	PSB5_YEAST	Proteasome component PRE2	9087403	Structure of 20S proteasome from yeast at 2.4-A resolution.

Q9C8G9	AB1C_ARATH	ABC transporter C family member 1	15215502	Isolation of intact vacuoles and proteomic analysis of tonoplast from suspension-cultured cells of Arabidopsis thaliana.

Q498H0	PD5BA_XENLA	Sister chromatid cohesion protein PDS5 homolog B-A	15855230	Functional contribution of Pds5 to cohesin-mediated cohesion in human cells and Xenopus egg extracts.

P37833	AATC_ORYSJ	Aspartate aminotransferase, cytoplasmic	9039500	Characterization and mapping of cDNA encoding aspartate aminotransferase in rice, Oryza sativa L.

Q07171	GELS_DROME	Gelsolin	8175883	Identification of secreted and cytosolic gelsolin in Drosophila.

Q92643	GPI8_HUMAN	GPI-anchor transamidase	12582175	Two subunits of glycosylphosphatidylinositol transamidase, GPI8 and PIG-T, form a functionally important intermolecular disulfide bridge.

Q9HDY2	YK18_SCHPO	Meiotically up-regulated protein PB1A10.08	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P27707	DCK_HUMAN	Deoxycytidine kinase	1996353	Cloning and expression of human deoxycytidine kinase cDNA.

Q8IN23	GR93B_DROME	Putative gustatory receptor 93b	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

P39676	FHP_YEAST	Flavohemoprotein	8810268	Function and expression of flavohemoglobin in Saccharomyces cerevisiae. Evidence for a role in the oxidative stress response.

Q9UT03	SLS1_SCHPO	Protein sls1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P50148	GNAQ_HUMAN	Guanine nucleotide-binding protein G(q) subunit alpha	8825633	Molecular cloning of human G alpha q cDNA and chromosomal localization of the G alpha q gene (GNAQ) and a processed pseudogene.

P87227	MIS6_SCHPO	Inner centromere protein mis6	10398680	Proper metaphase spindle length is determined by centromere proteins Mis12 and Mis6 required for faithful chromosome segregation.

Q9C0K7	STRAB_HUMAN	STE20-related kinase adapter protein beta	14517248	MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm.

P06149	DLD_ECOLI	D-lactate dehydrogenase	10944213	The crystal structure of D-lactate dehydrogenase, a peripheral membrane respiratory enzyme.

P11506	AT2B2_RAT	Plasma membrane calcium-transporting ATPase 2	2837461	Molecular cloning of two isoforms of the plasma membrane Ca2+- transporting ATPase from rat brain. Structural and functional domains exhibit similarity to Na+,K+- and other cation transport ATPases.

Q13315	ATM_HUMAN	Serine-protein kinase ATM	16086026	Regulated degradation of replication-dependent histone mRNAs requires both ATR and Upf1.

Q68KI4	NHX1_ARATH	Sodium/hydrogen exchanger 1	14535887	Vacuolar cation/H(+) exchange, ion homeostasis, and leaf development are altered in a T-DNA insertional mutant of AtNHX1, the Arabidopsis vacuolar Na(+)/H(+) antiporter.

Q03164	MLL1_HUMAN	Histone-lysine N-methyltransferase MLL	19187761	Structural basis for the requirement of additional factors for MLL1 SET domain activity and recognition of epigenetic marks.

P41318	LST8_YEAST	Target of rapamycin complex subunit LST8	12408816	Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control.

P85052	BUD25_YEAST	Bud site selection protein 25	11452010	A genomic study of the bipolar bud site selection pattern in Saccharomyces cerevisiae.

P36019	YPT53_YEAST	GTP-binding protein YPT53	8163546	Role of three rab5-like GTPases, Ypt51p, Ypt52p, and Ypt53p, in the endocytic and vacuolar protein sorting pathways of yeast.

Q42551	SCE1_ARATH	SUMO-conjugating enzyme SCE1	19682286	The Arabidopsis SUMO E3 ligase AtMMS21, a homologue of NSE2/MMS21, regulates cell proliferation in the root.

P01604	KV112_HUMAN	Ig kappa chain V-I region Kue	112021	The primary structure of the Bence-Jones protein Kue. The amino acid sequence of the variable part of a human L-chain of the kappa-type.

P54792	DVL1L_HUMAN	Segment polarity protein dishevelled homolog DVL-1-like	8644734	Human homologue sequences to the Drosophila dishevelled segment- polarity gene are deleted in the DiGeorge syndrome.

P32755	HPPD_RAT	4-hydroxyphenylpyruvate dioxygenase	12867153	Tissue distribution, intracellular localization and proteolytic processing of rat 4-hydroxyphenylpyruvate dioxygenase.

Q08949	DDC1_YEAST	DNA damage checkpoint protein 1	9891048	Role of a complex containing Rad17, Mec3, and Ddc1 in the yeast DNA damage checkpoint pathway.

P07358	CO8B_HUMAN	Complement component C8 beta chain	2820472	Complementary DNA and derived amino acid sequence of the beta subunit of human complement protein C8: identification of a close structural and ancestral relationship to the alpha subunit and C9.

P42813	RNS1_ARATH	Ribonuclease 1	8000425	The Arabidopsis ribonuclease gene RNS1 is tightly controlled in response to phosphate limitation.

Q71A39	PHLP1_DICDI	Phosducin-like protein 1	16135826	The phosducin-like protein PhLP1 is essential for Gbetagamma dimer formation in Dictyostelium discoideum.

P14755	CRYL1_RABIT	Lambda-crystallin	15809331	Structural and functional chracterization of rabbit and human L- gulonate 3-dehydrogenase.

Q9QY36	NAA10_MOUSE	N-alpha-acetyltransferase 10, NatA catalytic subunit	12888564	An evolutionarily conserved N-terminal acetyltransferase complex associated with neuronal development.

B3F211	IBP2B_DANRE	Insulin-like growth factor-binding protein 2-B	19081843	Duplication of the IGFBP-2 gene in teleost fish: protein structure and functionality conservation and gene expression divergence.

P11632	NHP6A_YEAST	Non-histone chromosomal protein 6A	16407207	Nhp6 is a transcriptional initiation fidelity factor for RNA polymerase III transcription in vitro and in vivo.

Q9Y5U5	TNR18_HUMAN	Tumor necrosis factor receptor superfamily member 18	10074428	Identification of a new member of the tumor necrosis factor family and its receptor, a human ortholog of mouse GITR.

Q3TZW7	BEX6_MOUSE	Protein BEX6	15958283	Characterization of the Bex gene family in humans, mice, and rats.

Q06643	TNFC_HUMAN	Lymphotoxin-beta	7916655	Lymphotoxin beta, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surface.

Q9BQ15	SOSB1_HUMAN	SOSS complex subunit B1	18449195	Single-stranded DNA-binding protein hSSB1 is critical for genomic stability.

O43752	STX6_HUMAN	Syntaxin-6	11384996	Association of a novel PDZ domain-containing peripheral Golgi protein with the Q-SNARE (Q-soluble N-ethylmaleimide-sensitive fusion protein (NSF) attachment protein receptor) protein syntaxin 6.

Q9SEL7	DEGP5_ARATH	Protease Do-like 5, chloroplastic	11719511	Proteome map of the chloroplast lumen of Arabidopsis thaliana.

Q8WXG6	MADD_HUMAN	MAP kinase-activating death domain protein	8988362	DENN, a novel human gene differentially expressed in normal and neoplastic cells.

P21128	ENDOU_HUMAN	Poly(U)-specific endoribonuclease	1710108	Homology of placental protein 11 and pea seed albumin 2 with vitronectin.

P0A935	MLTA_ECOLI	Membrane-bound lytic murein transglycosylase A	8288527	Purification and properties of a membrane-bound lytic transglycosylase from Escherichia coli.

P20263	PO5F1_MOUSE	POU domain, class 5, transcription factor 1	17097055	Inhibition of DNA binding of Sox2 by the SUMO conjugation.

Q672K1	NOX3_RAT	NADPH oxidase 3	15326186	NOX3, a superoxide-generating NADPH oxidase of the inner ear.

Q15691	MARE1_HUMAN	Microtubule-associated protein RP/EB family member 1	19632184	An EB1-binding motif acts as a microtubule tip localization signal.

P26842	CD27_HUMAN	CD27 antigen	9177220	CD27, a member of the tumor necrosis factor receptor family, induces apoptosis and binds to Siva, a proapoptotic protein.

P36053	ELF1_YEAST	Transcription elongation factor 1	16260625	Identification and characterization of Elf1, a conserved transcription elongation factor in Saccharomyces cerevisiae.

Q99207	NOP14_YEAST	Nucleolar complex protein 14	12068309	A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis.

Q8BMT9	HHAT_MOUSE	Protein-cysteine N-palmitoyltransferase HHAT	15075292	Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and long-range signaling in vertebrates.

Q8GX78	ANTR2_ARATH	Probable anion transporter 2, chloroplastic	14564522	Characterization of a protein of the plastid inner envelope having homology to animal inorganic phosphate, chloride and organic-anion transporters.

Q61233	PLSL_MOUSE	Plastin-2	14756805	Microglia/macrophage-specific protein Iba1 binds to fimbrin and enhances its actin-bundling activity.

P0ABQ2	GARR_ECOLI	2-hydroxy-3-oxopropionate reductase	9772162	Evolution of enzymatic activities in the enolase superfamily: characterization of the (D)-glucarate/galactarate catabolic pathway in Escherichia coli.

Q8W4E1	RH47_ARATH	DEAD-box ATP-dependent RNA helicase 47, mitochondrial	19805190	Loss of the plant DEAD-box protein ISE1 leads to defective mitochondria and increased cell-to-cell transport via plasmodesmata.

Q9LPF6	PUP11_ARATH	Probable purine permease 11	10662864	A new family of high-affinity transporters for adenine, cytosine, and purine derivatives in Arabidopsis.

Q68CZ6	HAUS3_HUMAN	HAUS augmin-like complex subunit 3	19427217	HAUS, the 8-subunit human augmin complex, regulates centrosome and spindle integrity.

Q8LBP4	ALB3_ARATH	Inner membrane protein ALBINO3, chloroplastic	14517205	Functional interaction of chloroplast SRP/FtsY with the ALB3 translocase in thylakoids: substrate not required.

A1Z6L1	TO402_DROME	Mitochondrial import receptor subunit TOM40 homolog 2	15304338	Germ-line specific variants of components of the mitochondrial outer membrane import machinery in Drosophila.

Q12354	APTH1_YEAST	Acyl-protein thioesterase 1	14562095	Global analysis of protein localization in budding yeast.

Q9SEI0	WER_ARATH	Transcription factor WER	10589676	WEREWOLF, a MYB-related protein in Arabidopsis, is a position- dependent regulator of epidermal cell patterning.

Q9Y048	DTN1_CAEEL	Dystrobrevin-1	11895430	Dystrobrevin requires a dystrophin-binding domain to function in Caenorhabditis elegans.

Q9HAV5	TNR27_HUMAN	Tumor necrosis factor receptor superfamily member 27	11039935	Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors.

Q15257	PTPA_HUMAN	Serine/threonine-protein phosphatase 2A activator	8195217	Molecular cloning, expression, and characterization of PTPA, a protein that activates the tyrosyl phosphatase activity of protein phosphatase 2A.

Q9U489	LIN41_CAEEL	Protein lin-41	16806150	Novel gain-of-function alleles demonstrate a role for the heterochronic gene lin-41 in C. elegans male tail tip morphogenesis.

Q9FZ48	UBC36_ARATH	Ubiquitin-conjugating enzyme E2 36	18178771	Arabidopsis UEV1D promotes lysine-63-linked polyubiquitination and is involved in DNA damage response.

P35922	FMR1_MOUSE	Fragile X mental retardation protein 1 homolog	18805096	The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP.

P12821	ACE_HUMAN	Angiotensin-converting enzyme	2849100	Two putative active centers in human angiotensin I-converting enzyme revealed by molecular cloning.

P25594	VBA3_YEAST	Vacuolar basic amino acid transporter 3	15572352	A family of basic amino acid transporters of the vacuolar membrane from Saccharomyces cerevisiae.

O60669	MOT2_HUMAN	Monocarboxylate transporter 2	9786900	Human monocarboxylate transporter 2 (MCT2) is a high affinity pyruvate transporter.

P16303	CES3_RAT	Carboxylesterase 3	11429416	Mutation of residues 423 (Met/Ile), 444 (Thr/Met), and 506 (Asn/Ser) confer cholesteryl esterase activity on rat lung carboxylesterase. Ser-506 is required for activation by cAMP-dependent protein kinase.

Q55354	PSBL_SYNY3	Photosystem II reaction center protein L	12069591	Proteomic analysis of a highly active photosystem II preparation from the cyanobacterium Synechocystis sp. PCC 6803 reveals the presence of novel polypeptides.

Q12305	YO285_YEAST	Putative thiosulfate sulfurtransferase YOR285W	16407407	Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins.

Q92626	PXDN_HUMAN	Peroxidasin homolog	18929642	Identification and characterization of VPO1, a new animal heme- containing peroxidase.

Q08743	YO292_YEAST	Vacuolar membrane protein YOR292C	14562095	Global analysis of protein localization in budding yeast.

P15112	EF2_DICDI	Elongation factor 2	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q9H7Z6	MYST1_HUMAN	Probable histone acetyltransferase MYST1	15960975	Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

Q5BDP1	RSP5_EMENI	E3 ubiquitin-protein ligase RSP5	15255903	A role for creD, a carbon catabolite repression gene from Aspergillus nidulans, in ubiquitination.

Q9JI99	SGPP1_MOUSE	Sphingosine-1-phosphate phosphatase 1	10859351	Molecular cloning and characterization of a lipid phosphohydrolase that degrades sphingosine-1-phosphate and induces cell death.

Q8BUK6	HOOK3_MOUSE	Protein Hook homolog 3	17237231	The microtubule-binding protein Hook3 interacts with a cytoplasmic domain of scavenger receptor A.

P83522	FER_HORVU	Ferredoxin	1367267	The amino acid sequence of ferredoxin from Hordeum vulgare.

Q91550	ILF3A_XENLA	Interleukin enhancer-binding factor 3-A	10899122	RNA-dependent cytoplasmic anchoring of a transcription factor subunit during Xenopus development.

Q9D3R9	TAF7L_MOUSE	Transcription initiation factor TFIID subunit 7-like	17242199	Abnormal sperm in mice lacking the Taf7l gene.

Q9WU70	STXB5_RAT	Syntaxin-binding protein 5	9620695	Tomosyn: a syntaxin-1-binding protein that forms a novel complex in the neurotransmitter release process.

P54578	UBP14_HUMAN	Ubiquitin carboxyl-terminal hydrolase 14	19106094	Deubiquitination of CXCR4 by USP14 is critical for both CXCL12- induced CXCR4 degradation and chemotaxis but not ERK ativation.

Q99216	PNO1_YEAST	Pre-rRNA-processing protein PNO1	12736301	RRP20, a component of the 90S preribosome, is required for pre-18S rRNA processing in Saccharomyces cerevisiae.

Q92339	GHT3_SCHPO	High-affinity gluconate transporter ght3	10735857	Multiple hexose transporters of Schizosaccharomyces pombe.

O13987	YEG5_SCHPO	Ankyrin and IPT/TIG repeat-containing protein C26H5.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

B4ZIX8	SCC4_XENLA	Cohesin loading complex subunit SCC4 homolog	16682347	Human Scc4 is required for cohesin binding to chromatin, sister- chromatid cohesion, and mitotic progression.

O00299	CLIC1_HUMAN	Chloride intracellular channel protein 1	10793131	Identification of a novel member of the chloride intracellular channel gene family (CLIC5) that associates with the actin cytoskeleton of placental microvilli.

Q9WTW5	S22A3_MOUSE	Solute carrier family 22 member 3	9933568	Cloning of the mouse and human solute carrier 22a3 (Slc22a3/SLC22A3) identifies a conserved cluster of three organic cation transporters on mouse chromosome 17 and human 6q26-q27.

Q12745	SEC39_YEAST	Protein transport protein SEC39	16429126	Proteome survey reveals modularity of the yeast cell machinery.

Q12328	TIM22_YEAST	Mitochondrial import inner membrane translocase subunit TIM22	11864609	Tim22, the essential core of the mitochondrial protein insertion complex, forms a voltage-activated and signal-gated channel.

Q09715	TUP11_SCHPO	Transcriptional repressor tup11	10567571	Conservation of histone binding and transcriptional repressor functions in a Schizosaccharomyces pombe Tup1p homolog.

Q8INF0	GCY8E_DROME	Soluble guanylate cyclase 88E	15485853	Atypical soluble guanylyl cyclases in Drosophila can function as molecular oxygen sensors.

Q9GTN7	TAGA_DICDI	Serine protease/ABC transporter B family protein tagA	17056744	Genetic evidence that the acyl coenzyme A binding protein AcbA and the serine protease/ABC transporter TagA function together in Dictyostelium discoideum cell differentiation.

O09053	WRN_MOUSE	Werner syndrome ATP-dependent helicase homolog	11301316	A novel protein interacts with the Werner's syndrome gene product physically and functionally.

P97613	PTTG1_RAT	Securin	9092795	Isolation and characterization of a pituitary tumor-transforming gene (PTTG).

P36107	AUR1_YEAST	Inositol phosphorylceramide synthase	10888667	Inositol phosphorylceramide synthase is located in the Golgi apparatus of Saccharomyces cerevisiae.

O60911	CATL2_HUMAN	Cathepsin L2	9563472	Cathepsin L2, a novel human cysteine proteinase produced by breast and colorectal carcinomas.

Q96QU6	1A1L1_HUMAN	1-aminocyclopropane-1-carboxylate synthase-like protein 1	11470512	The human cDNA for a homologue of the plant enzyme 1- aminocyclopropane-1-carboxylate synthase encodes a protein lacking that activity.

P82251	BAT1_HUMAN	B(0,+)-type amino acid transporter 1	10471498	Non-type I cystinuria caused by mutations in SLC7A9, encoding a subunit (b0,+AT) of rBAT.

P14741	EI2BA_YEAST	Translation initiation factor eIF-2B subunit alpha	8506384	A protein complex of translational regulators of GCN4 mRNA is the guanine nucleotide-exchange factor for translation initiation factor 2 in yeast.

P39988	BUD16_YEAST	Putative pyridoxal kinase BUD16	11452010	A genomic study of the bipolar bud site selection pattern in Saccharomyces cerevisiae.

P83257	TXDP2_PIRLC	Delta-amaurobitoxin-Pl1b	10971590	Isolation, synthesis and pharmacological characterization of delta- palutoxins IT, novel insecticidal toxins from the spider Paracoelotes luctuosus (Amaurobiidae).

Q1LK00	T23O_RALME	Tryptophan 2,3-dioxygenase	17198384	Crystal structure and mechanism of tryptophan 2,3-dioxygenase, a heme enzyme involved in tryptophan catabolism and in quinolinate biosynthesis.

P0A870	TALB_ECOLI	Transaldolase B	7592346	Transaldolase B of Escherichia coli K-12: cloning of its gene, talB, and characterization of the enzyme from recombinant strains.

P29122	PCSK6_HUMAN	Proprotein convertase subtilisin/kexin type 6	9738469	Biosynthetic processing and quaternary interactions of proprotein convertase SPC4 (PACE4).

Q9ER35	FN3K_MOUSE	Fructosamine-3-kinase	11016445	Identification, cloning, and heterologous expression of a mammalian fructosamine-3-kinase.

Q9LJM4	IKU2_ARATH	Receptor-like protein kinase HAIKU2	12692325	Arabidopsis haiku mutants reveal new controls of seed size by endosperm.

P01597	KV105_HUMAN	Ig kappa chain V-I region DEE	5124396	The amino acid sequence of a human kappa light chain.

Q9PUK8	FZD7A_XENLA	Frizzled-7-A	10751186	The putative Wnt receptor Xenopus frizzled-7 functions upstream of beta-catenin in vertebrate dorso-ventral mesoderm patterning.

Q60592	MAST2_MOUSE	Microtubule-associated serine/threonine-protein kinase 2	8246979	A novel 205-kDa testis-specific serine/threonine protein kinase associated with microtubules of the spermatid manchette.

P10849	MTF2_YEAST	Mitochondrial transcription factor 2	8413192	The NAM1/MTF2 nuclear gene product is selectively required for the stability and/or processing of mitochondrial transcripts of the atp6 and of the mosaic, cox1 and cytb genes in Saccharomyces cerevisiae.

P48430	SOX2_CHICK	Transcription factor SOX-2	7628452	Involvement of SOX proteins in lens-specific activation of crystallin genes.

Q8VHP7	ILEUB_MOUSE	Leukocyte elastase inhibitor B	12189154	Characterization of four murine homologs of the human ov-serpin monocyte neutrophil elastase inhibitor MNEI (SERPINB1).

P21623	DIT1_YEAST	Spore wall maturation protein DIT1	8183942	The sporulation-specific enzymes encoded by the DIT1 and DIT2 genes catalyze a two-step reaction leading to a soluble LL-dityrosine- containing precursor of the yeast spore wall.

P12956	XRCC6_HUMAN	X-ray repair cross-complementing protein 6	1537839	Identification of proteins binding to interferon-inducible transcriptional enhancers in hematopoietic cells.

P0AAR3	YBAK_ECOLI	Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase ybaK	14663147	Trans-editing of mischarged tRNAs.

Q9LZY0	MA654_ARATH	65-kDa microtubule-associated protein 4	19060108	The C-terminal variable region specifies the dynamic properties of Arabidopsis microtubule-associated protein MAP65 isotypes.

Q9LVM1	AB25B_ARATH	ABC transporter B family member 25, mitochondrial	16461380	AtATM3 is involved in heavy metal resistance in Arabidopsis.

P35125	UBP6_HUMAN	Ubiquitin carboxyl-terminal hydrolase 6	1565468	A novel transcriptional unit of the tre oncogene widely expressed in human cancer cells.

Q96Q83	ALKB3_HUMAN	Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3	12486230	Reversal of DNA alkylation damage by two human dioxygenases.

P31016	DLG4_RAT	Disks large homolog 4	16990550	Epilepsy-related ligand/receptor complex LGI1 and ADAM22 regulate synaptic transmission.

O76096	CYTF_HUMAN	Cystatin-F	9733783	Cystatin F is a glycosylated human low molecular weight cysteine proteinase inhibitor.

O57311	ZIC3_XENLA	Zinc finger protein ZIC 3	11869292	Xenopus Brachyury regulates mesodermal expression of Zic3, a gene controlling left-right asymmetry.

Q15818	NPTX1_HUMAN	Neuronal pentraxin-1	8884281	Mouse and human neuronal pentraxin 1 (NPTX1): conservation, genomic structure, and chromosomal localization.

Q9Y2I7	FYV1_HUMAN	1-phosphatidylinositol-3-phosphate 5-kinase	17556371	Core protein machinery for mammalian phosphatidylinositol 3,5- bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complex.

Q12303	YPS3_YEAST	Aspartic proteinase yapsin-3	10191273	Identification and characterization of Saccharomyces cerevisiae yapsin 3, a new member of the yapsin family of aspartic proteases encoded by the YPS3 gene.

O36018	BUD22_SCHPO	BUD22 family protein C4F10.06	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q04207	TF65_MOUSE	Transcription factor p65	11931770	Peptide-induced negative selection of thymocytes activates transcription of an NF-kappa B inhibitor.

P01588	EPO_HUMAN	Erythropoietin	3838366	Isolation and characterization of genomic and cDNA clones of human erythropoietin.

P62955	CCG7_HUMAN	Voltage-dependent calcium channel gamma-7 subunit	11170751	A cluster of three novel Ca(2+) channel gamma subunit genes on chromosome 19q13.4: evolution and expression profile of the gamma subunit gene family.

Q9URW7	VPS17_SCHPO	Vacuolar protein sorting-associated protein 17	16622069	Vacuolar protein sorting receptor in Schizosaccharomyces pombe.

Q9FMD9	GLN14_ARATH	Glutamine synthetase cytosolic isozyme 1-4	14757761	Kinetic properties and ammonium-dependent regulation of cytosolic isoenzymes of glutamine synthetase in Arabidopsis.

P21731	TA2R_HUMAN	Thromboxane A2 receptor	19464661	Thromboxane A2-induced signal transduction is negatively regulated by KIAA1005 that directly interacts with thromboxane A2 receptor.

Q04217	DHR1_YEAST	Probable ATP-dependent RNA helicase DHR1	12068309	A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis.

P53996	CNBP_MOUSE	Cellular nucleic acid-binding protein	7896269	Mouse cellular nucleic acid binding proteins: a highly conserved family identified by genetic mapping and sequencing.

P24158	PRTN3_HUMAN	Myeloblastin	2679910	Wegener's granulomatosis autoantigen is a novel neutrophil serine proteinase.

Q02521	SPP2_YEAST	Pre-mRNA-splicing factor SPP2	7493316	The final stages of spliceosome maturation require Spp2p that can interact with the DEAH box protein Prp2p and promote step 1 of splicing.

P63167	DYL1_HUMAN	Dynein light chain 1, cytoplasmic	8628263	Cytoplasmic dynein (ddlc1) mutations cause morphogenetic defects and apoptotic cell death in Drosophila melanogaster.

P15702	LEUK_MOUSE	Leukosialin	7514104	A unique murine CD43 epitope Lp-3: distinct distribution from another CD43 epitope S7.

O49543	NFS1_ARATH	Cysteine desulfurase 1, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P38771	RRF1_YEAST	Ribosome-recycling factor, mitochondrial	12853640	Temperature-sensitive mutation in yeast mitochondrial ribosome recycling factor (RRF).

P15700	UMPK_YEAST	Uridylate kinase	8391780	Characteristics, substrate analysis, and intracellular location of Saccharomyces cerevisiae UMP kinase.

P25098	ARBK1_HUMAN	Beta-adrenergic receptor kinase 1	19306925	Dual regulation of lysophosphatidic acid (LPA1) receptor signalling by Ral and GRK.

Q5AVN4	PLYA_EMENI	Pectate lyase A	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

Q14435	GALT3_HUMAN	Polypeptide N-acetylgalactosaminyltransferase 3	8663203	cDNA cloning and expression of a novel human UDP-N-acetyl-alpha-D- galactosamine polypeptide N-acetylgalactosaminyltransferase, GalNAc- T3.

P05178	CP2C6_RAT	Cytochrome P450 2C6	3015936	Sequence of two related P-450 mRNAs transcriptionally increased during rat development. An R.dre.1 sequence occupies the complete 3' untranslated region of a liver mRNA.

O43318	M3K7_HUMAN	Mitogen-activated protein kinase kinase kinase 7	11460167	TAK1 is a ubiquitin-dependent kinase of MKK and IKK.

O15212	PFD6_HUMAN	Prefoldin subunit 6	9630229	Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin.

O94875	SRBS2_HUMAN	Sorbin and SH3 domain-containing protein 2	9211900	ArgBP2, a multiple Src homology 3 domain-containing, Arg/Abl- interacting protein, is phosphorylated in v-Abl-transformed cells and localized in stress fibers and cardiocyte Z-disks.

P30260	CDC27_HUMAN	Cell division cycle protein 27 homolog	18485873	Mechanism of ubiquitin-chain formation by the human anaphase- promoting complex.

P26599	PTBP1_HUMAN	Polypyrimidine tract-binding protein 1	1906036	Characterization and molecular cloning of polypyrimidine tract- binding protein: a component of a complex necessary for pre-mRNA splicing.

O96008	TOM40_HUMAN	Mitochondrial import receptor subunit TOM40 homolog	15644312	Dissection of the mitochondrial import and assembly pathway for human Tom40.

P13232	IL7_HUMAN	Interleukin-7	2643102	Human interleukin 7: molecular cloning and growth factor activity on human and murine B-lineage cells.

Q12019	MDN1_YEAST	Midasin	12102729	Expression and genomic analysis of midasin, a novel and highly conserved AAA protein distantly related to dynein.

Q10205	RRP43_SCHPO	Exosome complex component rrp43	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q94918	VEIN_DROME	Protein vein	8824589	Vein is a novel component in the Drosophila epidermal growth factor receptor pathway with similarity to the neuregulins.

Q00582	GTR1_YEAST	GTP-binding protein GTR1	16732272	A conserved GTPase-containing complex is required for intracellular sorting of the general amino-acid permease in yeast.

Q9DDK4	S1PR1_DANRE	Sphingosine 1-phosphate receptor 1	11112429	Characterization of a zebrafish (Danio rerio) sphingosine 1-phosphate receptor expressed in the embryonic brain.

Q20060	SMC4_CAEEL	Structural maintenance of chromosomes protein 4	11914278	C. elegans condensin promotes mitotic chromosome architecture, centromere organization, and sister chromatid segregation during mitosis and meiosis.

Q14155	ARHG7_HUMAN	Rho guanine nucleotide exchange factor 7	15182672	Mammalian Scribble forms a tight complex with the betaPIX exchange factor.

Q14242	SELPL_HUMAN	P-selectin glycoprotein ligand 1	7541799	Genomic organization and chromosomal localization of the gene encoding human P-selectin glycoprotein ligand.

Q14974	IMB1_HUMAN	Importin subunit beta-1	7627554	Two different subunits of importin cooperate to recognize nuclear localization signals and bind them to the nuclear envelope.

Q9R088	KITM_MOUSE	Thymidine kinase 2, mitochondrial	10571069	Cloning of mouse mitochondrial thymidine kinase 2 cDNA.

P53734	DBP6_YEAST	ATP-dependent RNA helicase DBP6	9528757	Dbp6p is an essential putative ATP-dependent RNA helicase required for 60S-ribosomal-subunit assembly in Saccharomyces cerevisiae.

Q8N3I7	BBS5_HUMAN	Bardet-Biedl syndrome 5 protein	17574030	A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis.

Q9NPB1	NT5M_HUMAN	5'(3')-deoxyribonucleotidase, mitochondrial	10899995	A deoxyribonucleotidase in mitochondria: involvement in regulation of dNTP pools and possible link to genetic disease.

Q9MA15	Y1960_ARATH	Uncharacterized aarF domain-containing protein kinase At1g79600, chloroplastic	16414959	Tocopherol cyclase (VTE1) localization and vitamin E accumulation in chloroplast plastoglobule lipoprotein particles.

P38631	FKS1_YEAST	1,3-beta-glucan synthase component FKS1	11856368	Movement of yeast 1,3-beta-glucan synthase is essential for uniform cell wall synthesis.

Q06245	SEC10_YEAST	Exocyst complex component SEC10	8978675	The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae.

P25815	S100P_HUMAN	Protein S100-P	15632002	Expression of S100P and its novel binding partner S100PBPR in early pancreatic cancer.

Q8K0T2	DC2L1_MOUSE	Cytoplasmic dynein 2 light intermediate chain 1	15371312	Targeted deletion of the novel cytoplasmic dynein mD2LIC disrupts the embryonic organiser, formation of the body axes and specification of ventral cell fates.

Q8NC51	PAIRB_HUMAN	Plasminogen activator inhibitor 1 RNA-binding protein	12505151	Characterization of a new family of proteins that interact with the C-terminal region of the chromatin-remodeling factor CHD-3.

Q80U72	SCRIB_MOUSE	Protein scribble homolog	19041750	Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma.

P24386	RAE1_HUMAN	Rab proteins geranylgeranyltransferase component A 1	7981670	Cloning and characterization of the human choroideremia gene.

P52488	UBA2_YEAST	Ubiquitin-activating enzyme E1-like	7629121	An essential yeast gene encoding a homolog of ubiquitin-activating enzyme.

P06399	FIBA_RAT	Fibrinogen alpha chain	3817019	Molecular cloning of mRNA sequences transiently induced during rat liver regeneration.

O44342	WBL_DROME	Protein windbeutel	15252019	Mapping of a substrate binding site in the protein disulfide isomerase-related chaperone wind based on protein function and crystal structure.

P38881	NVJ1_YEAST	Nucleus-vacuole junction protein 1	12529432	Piecemeal microautophagy of nucleus in Saccharomyces cerevisiae.

Q15391	P2Y14_HUMAN	P2Y purinoceptor 14	10753868	A G protein-coupled receptor for UDP-glucose.

Q9ESW4	AGK_MOUSE	Acylglycerol kinase, mitochondrial	15252046	MuLK, a eukaryotic multi-substrate lipid kinase.

P0ABU9	TOLQ_ECOLI	Protein tolQ	8331075	Membrane topologies of the TolQ and TolR proteins of Escherichia coli: inactivation of TolQ by a missense mutation in the proposed first transmembrane segment.

O00468	AGRIN_HUMAN	Agrin	9652404	Primary structure and high expression of human agrin in basement membranes of adult lung and kidney.

Q12525	MHT1_YEAST	Homocysteine S-methyltransferase 1	14562095	Global analysis of protein localization in budding yeast.

O82595	NGA4_ARATH	B3 domain-containing transcription factor NGA4	16603651	Endogenous and synthetic microRNAs stimulate simultaneous, efficient, and localized regulation of multiple targets in diverse species.

Q9NVV9	THAP1_HUMAN	THAP domain-containing protein 1	17003378	The THAP-zinc finger protein THAP1 regulates endothelial cell proliferation through modulation of pRB/E2F cell-cycle target genes.

Q00987	MDM2_HUMAN	E3 ubiquitin-protein ligase Mdm2	17290220	The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2.

Q9HCC0	MCCB_HUMAN	Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial	11170888	The molecular basis of 3-methylcrotonylglycinuria, a disorder of leucine catabolism.

Q9JII4	PR5A1_RAT	Prolactin-5A1	10471365	Identification of four members of the rat prolactin/growth hormone gene family.

Q9SR77	HBPL1_ARATH	Heme-binding-like protein At3g10130, chloroplastic	16461379	Protein profiling of plastoglobules in chloroplasts and chromoplasts. A surprising site for differential accumulation of metabolic enzymes.

Q62070	PIM2_MOUSE	Serine/threonine-protein kinase pim-2	15548703	Lymphocyte transformation by Pim-2 is dependent on nuclear factor- kappaB activation.

O74458	SFC4_SCHPO	Transcription factor tau subunit sfc4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q14507	EP3A_HUMAN	Epididymal secretory protein E3-alpha	7514008	Major human epididymis-specific gene product, HE3, is the first representative of a novel gene family.

Q9VQS6	DRM_DROME	Protein drumstick	12117814	Drumstick is a zinc finger protein that antagonizes Lines to control patterning and morphogenesis of the Drosophila hindgut.

Q6PDG8	MON1A_MOUSE	Vacuolar fusion protein MON1 homolog A	17632513	Genetic variation in Mon1a affects protein trafficking and modifies macrophage iron loading in mice.

Q9JJG5	SRTD2_MOUSE	SERTA domain-containing protein 2	11331592	TRIP-Br: a novel family of PHD zinc finger- and bromodomain- interacting proteins that regulate the transcriptional activity of E2F-1/DP-1.

P53173	ERV14_YEAST	ER-derived vesicles protein ERV14	9732282	Transport of axl2p depends on erv14p, an ER-vesicle protein related to the Drosophila cornichon gene product.

Q6TU48	MAOX_DICDI	NADP-dependent malic enzyme	14665466	Dictyostelium discoideum developmentally regulated genes whose expression is dependent on MADS box transcription factor SrfA.

P54619	AAKG1_HUMAN	5'-AMP-activated protein kinase subunit gamma-1	18403135	Identification and characterization of a novel folliculin-interacting protein FNIP2.

P19491	GRIA2_RAT	Glutamate receptor 2	10414981	Association of AMPA receptors with a subset of glutamate receptor- interacting protein in vivo.

Q12055	KAD6_YEAST	Putative adenylate kinase FAP7	10692169	The essential protein fap7 is involved in the oxidative stress response of Saccharomyces cerevisiae.

P41920	YRB1_YEAST	Ran-specific GTPase-activating protein 1	7836422	Ran-binding protein-1 is an essential component of the Ran/RCC1 molecular switch system in budding yeast.

Q12202	OSW2_YEAST	Outer spore wall protein 2	15590821	Morphogenetic pathway of spore wall assembly in Saccharomyces cerevisiae.

P22725	WNT5A_MOUSE	Protein Wnt-5a	10021340	A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo.

Q9QYW1	KCNN4_RAT	Intermediate conductance calcium-activated potassium channel protein 4	10532960	Molecular cloning and characterization of the intermediate- conductance Ca(2+)-activated K(+) channel in vascular smooth muscle: relationship between K(Ca) channel diversity and smooth muscle cell function.

Q6IQ23	PKHA7_HUMAN	Pleckstrin homology domain-containing family A member 7	19041755	Anchorage of microtubule minus ends to adherens junctions regulates epithelial cell-cell contacts.

P47929	LEG7_HUMAN	Galectin-7	7534301	Cloning, expression, and chromosome mapping of human galectin-7.

P18480	SNF5_YEAST	SWI/SNF chromatin-remodeling complex subunit SNF5	2233708	The SNF5 protein of Saccharomyces cerevisiae is a glutamine- and proline-rich transcriptional activator that affects expression of a broad spectrum of genes.

Q8I7T3	SADA_DICDI	Substrate-adhesion molecule	12499361	SadA, a novel adhesion receptor in Dictyostelium.

Q9BUJ2	HNRL1_HUMAN	Heterogeneous nuclear ribonucleoprotein U-like protein 1	15907477	The interaction of the hnRNP family member E1B-AP5 with p53.

P49023	PAXI_HUMAN	Paxillin	20489202	Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity.

Q8LBZ7	DHSB1_ARATH	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit 1, mitochondrial	11442063	Three different genes encode the iron-sulphur subunit of succinate dehydrogenase in Arabidopsis thaliana.

Q63651	RK_RAT	Rhodopsin kinase	9147475	Molecular cloning and localization of rhodopsin kinase in the mammalian pineal.

O43916	CHST1_HUMAN	Carbohydrate sulfotransferase 1	9639683	Human chondroitin 6-sulfotransferase: cloning, gene structure, and chromosomal localization.

Q55GJ6	PSB6_DICDI	Proteasome subunit beta type-6	8130037	Proteasomes from Dictyostelium discoideum: characterization of structure and function.

Q99638	RAD9A_HUMAN	Cell cycle checkpoint control protein RAD9A	10713044	Human DNA damage checkpoint protein hRAD9 is a 3' to 5' exonuclease.

Q06512	NOC4_YEAST	Nucleolar complex protein 4	12446671	A Noc complex specifically involved in the formation and nuclear export of ribosomal 40 S subunits.

Q9NPC2	KCNK9_HUMAN	Potassium channel subfamily K member 9	11042359	Cloning, localisation and functional expression of a novel human, cerebellum specific, two pore domain potassium channel.

O00463	TRAF5_HUMAN	TNF receptor-associated factor 5	10809768	TAJ, a novel member of the tumor necrosis factor receptor family, activates the c-Jun N-terminal kinase pathway and mediates caspase- independent cell death.

P63005	LIS1_MOUSE	Platelet-activating factor acetylhydrolase IB subunit alpha	11163258	LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome.

Q9USN5	DHE2_SCHPO	Putative NAD-specific glutamate dehydrogenase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12093	MTU1_YEAST	Mitochondrial tRNA-specific 2-thiouridylase 1	15509579	Mitochondria-specific RNA-modifying enzymes responsible for the biosynthesis of the wobble base in mitochondrial tRNAs. Implications for the molecular pathogenesis of human mitochondrial diseases.

Q9SLB7	LBD16_ARATH	LOB domain-containing protein 16	17259263	ARF7 and ARF19 regulate lateral root formation via direct activation of LBD/ASL genes in Arabidopsis.

Q8IZQ8	MYCD_HUMAN	Myocardin	16054032	Phenotypic modulation of smooth muscle cells through interaction of Foxo4 and myocardin.

P00934	THRC_ECOLI	Threonine synthase	6316258	Nucleotide sequence of thrC and of the transcription termination region of the threonine operon in Escherichia coli K12.

Q80Z29	NAMPT_RAT	Nicotinamide phosphoribosyltransferase	16901503	Crystal structure of visfatin/pre-B cell colony-enhancing factor 1/nicotinamide phosphoribosyltransferase, free and in complex with the anti-cancer agent FK-866.

O62301	SMG8_CAEEL	Protein smg-8	19417104	SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay.

P32333	MOT1_YEAST	TATA-binding protein-associated factor MOT1	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P21964	COMT_HUMAN	Catechol O-methyltransferase	1707278	Cloning and characterization of human placental catechol-O- methyltransferase cDNA.

O60312	AT10A_HUMAN	Probable phospholipid-transporting ATPase VA	11353404	The human aminophospholipid-transporting ATPase gene ATP10C maps adjacent to UBE3A and exhibits similar imprinted expression.

P42677	RS27_HUMAN	40S ribosomal protein S27	8407955	A growth factor-inducible gene encodes a novel nuclear protein with zinc finger structure.

P47824	P2RX1_RAT	P2X purinoceptor 1	7523951	A new class of ligand-gated ion channel defined by P2x receptor for extracellular ATP.

O14836	TR13B_HUMAN	Tumor necrosis factor receptor superfamily member 13B	10956646	Tumor necrosis factor (TNF) receptor superfamily member TACI is a high affinity receptor for TNF family members APRIL and BLyS.

P40098	FMP10_YEAST	Uncharacterized mitochondrial membrane protein FMP10	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

O00148	DDX39_HUMAN	ATP-dependent RNA helicase DDX39	14667819	Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region.

P22460	KCNA5_HUMAN	Potassium voltage-gated channel subfamily A member 5	1986382	Sequence and functional expression in Xenopus oocytes of a human insulinoma and islet potassium channel.

P39929	SNF7_YEAST	Vacuolar-sorting protein SNF7	15086794	Protein-protein interactions of ESCRT complexes in the yeast Saccharomyces cerevisiae.

Q15915	ZIC1_HUMAN	Zinc finger protein ZIC 1	8542595	Predominant expression of human zic in cerebellar granule cell lineage and medulloblastoma.

P25846	MSH1_YEAST	DNA mismatch repair protein MSH1, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

O43148	MCES_HUMAN	mRNA cap guanine-N7 methyltransferase	9705270	Recombinant human mRNA cap methyltransferase binds capping enzyme/RNA polymerase IIo complexes.

Q86W24	NAL14_HUMAN	NACHT, LRR and PYD domains-containing protein 14	16931801	Mutations in the testis-specific NALP14 gene in men suffering from spermatogenic failure.

Q95Q95	TOR_CAEEL	Target of rapamycin homolog	14668850	Genetics: influence of TOR kinase on lifespan in C. elegans.

Q9USP9	YHP4_SCHPO	Uncharacterized RNA-binding protein C902.04	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

P50946	OCA1_YEAST	Putative tyrosine-protein phosphatase OCA1	11408586	Identification of a Saccharomyces cerevisiae gene that is required for G1 arrest in response to the lipid oxidation product linoleic acid hydroperoxide.

P40577	MND2_YEAST	Anaphase-promoting complex subunit MND2	12477395	Proteomics analysis identifies new components of the fission and budding yeast anaphase-promoting complexes.

P33748	MSN2_YEAST	Zinc finger protein MSN2	12090248	Yeast Whi2 and Psr1-phosphatase form a complex and regulate STRE- mediated gene expression.

P49723	RIR4_YEAST	Ribonucleoside-diphosphate reductase small chain 2	9315671	Rnr4p, a novel ribonucleotide reductase small-subunit protein.

Q924S5	LONM_RAT	Lon protease homolog, mitochondrial	12082077	Transmission of cell stress from endoplasmic reticulum to mitochondria: enhanced expression of Lon protease.

P35790	CHKA_HUMAN	Choline kinase alpha	19915674	Differential role of human choline kinase alpha and beta enzymes in lipid metabolism: implications in cancer onset and treatment.

Q01448	HPC2_YEAST	Histone promoter control protein 2	16264190	The HIR corepressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF.

Q91XJ0	CREST_RAT	Calcium-responsive transcription coactivator	15488321	The calcium-responsive transactivator recruits CREB binding protein to nuclear bodies.

Q10235	ALP11_SCHPO	Cell polarity protein alp11	10905343	Characterisation of fission yeast alp11 mutants defines three functional domains within tubulin-folding cofactor B.

Q05949	BUR2_YEAST	Protein BUR2	14562095	Global analysis of protein localization in budding yeast.

P28548	CSK2B_CAEEL	Casein kinase II subunit beta	16481400	Casein kinase II and calcineurin modulate TRPP function and ciliary localization.

P97946	VEGFD_MOUSE	Vascular endothelial growth factor D	8876195	Identification of a c-fos-induced gene that is related to the platelet-derived growth factor/vascular endothelial growth factor family.

Q5B833	MANB_EMENI	Mannan endo-1,4-beta-mannosidase B	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

P62913	RL11_HUMAN	60S ribosomal protein L11	7748210	Cloning and determination of the primary structure of DNA complementary to the mRNA of human ribosomal protein L11.

P40234	CKI2_SCHPO	Casein kinase I homolog 2	8163505	Cytoplasmic forms of fission yeast casein kinase-1 associate primarily with the particulate fraction of the cell.

Q9U1S7	PKD2_CAEEL	Polycystin-2	15563610	ATP-2 interacts with the PLAT domain of LOV-1 and is involved in Caenorhabditis elegans polycystin signaling.

P19971	TYPH_HUMAN	Thymidine phosphorylase	9924029	Thymidine phosphorylase gene mutations in MNGIE, a human mitochondrial disorder.

O49686	PYR1_ARATH	Abscisic acid receptor PYR1	19624469	Modulation of drought resistance by the abscisic acid receptor PYL5 through inhibition of clade A PP2Cs.

P45973	CBX5_HUMAN	Chromobox protein homolog 5	8663349	Interaction between an integral protein of the nuclear envelope inner membrane and human chromodomain proteins homologous to Drosophila HP1.

Q949J1	IPYR2_CHLRE	Soluble inorganic pyrophosphatase 2	16313235	A novel subfamily of monomeric inorganic pyrophosphatases in photosynthetic eukaryotes.

Q06156	CND1_YEAST	Condensin complex subunit 1	11854418	Mutation of YCS4, a budding yeast condensin subunit, affects mitotic and nonmitotic chromosome behavior.

Q93084	AT2A3_HUMAN	Sarcoplasmic/endoplasmic reticulum calcium ATPase 3	8809064	cDNA cloning, expression and chromosomal localization of the human sarco/endoplasmic reticulum Ca(2+)-ATPase 3 gene.

Q08408	RPRX_BACFR	Sensor protein rprX	8469117	Cloning and identification of a two-component signal-transducing regulatory system from Bacteroides fragilis.

P84212	BOML1_BOMVA	Bombesin-like peptide 1	15134346	Skin secretion of the toad Bombina variegata contains multiple insulin-releasing peptides including bombesin and entirely novel insulinotropic structures.

Q3E705	EFG1P_YEAST	rRNA-processing protein EFG1	12837249	A panoramic view of yeast noncoding RNA processing.

P22202	HSP74_YEAST	Heat shock protein SSA4	2121731	Structure and regulation of the SSA4 HSP70 gene of Saccharomyces cerevisiae.

P35739	NTRK1_RAT	High affinity nerve growth factor receptor	15167895	A unique pathway for sustained neurotrophin signaling through an ankyrin-rich membrane-spanning protein.

Q7RTX1	TS1R1_HUMAN	Taste receptor type 1 member 1	11917125	Human receptors for sweet and umami taste.

Q9WTZ3	MBTP1_RAT	Membrane-bound transcription factor site-1 protease	9990022	Mammalian subtilisin/kexin isozyme SKI-1: a widely expressed proprotein convertase with a unique cleavage specificity and cellular localization.

Q96276	MYB23_ARATH	Transcription factor MYB23	11437443	Ectopic expression of the Arabidopsis AtMYB23 gene induces differentiation of trichome cells.

P49916	DNLI3_HUMAN	DNA ligase 3	7565692	Mammalian DNA ligase III: molecular cloning, chromosomal localization, and expression in spermatocytes undergoing meiotic recombination.

P53865	CNM67_YEAST	Chaotic nuclear migration protein 67	11514632	Cnm67p is a spacer protein of the Saccharomyces cerevisiae spindle pole body outer plaque.

Q9BXM7	PINK1_HUMAN	Serine/threonine-protein kinase PINK1, mitochondrial	14607334	BRPK, a novel protein kinase showing increased expression in mouse cancer cell lines with higher metastatic potential.

Q9ERU3	ZNF22_MOUSE	Zinc finger protein 22	12952191	Developmental expression pattern and DNA-binding properties of the zinc finger transcription factor Krox-26.

P39946	NUDF_YEAST	Nuclear distribution protein PAC1	12566428	The role of the lissencephaly protein Pac1 during nuclear migration in budding yeast.

Q9Y5Y9	SCNAA_HUMAN	Sodium channel protein type 10 subunit alpha	9839820	A tetrodotoxin-resistant voltage-gated sodium channel from human dorsal root ganglia, hPN3/SCN10A.

O57848	ALAXM_PYRHO	Alanyl-tRNA editing protein AlaX-M	17327676	Structure of the AlaX-M trans-editing enzyme from Pyrococcus horikoshii.

Q09624	LOV1_CAEEL	Location of vulva defective 1	15563610	ATP-2 interacts with the PLAT domain of LOV-1 and is involved in Caenorhabditis elegans polycystin signaling.

Q3KNW5	SOAT_HUMAN	Solute carrier family 10 member 6	17491011	Cloning and functional characterization of human sodium-dependent organic anion transporter (SLC10A6).

P15791	KCC2D_RAT	Calcium/calmodulin-dependent protein kinase type II subunit delta	8390994	Identification of novel isoforms of the delta subunit of Ca2+/calmodulin-dependent protein kinase II. Differential expression in rat brain and aorta.

P50079	HSV2_YEAST	SVP1-like protein 2	18769150	Dissecting the localization and function of Atg18, Atg21 and Ygr223c.

Q42484	RPS2_ARATH	Disease resistance protein RPS2	11204781	Mutational analysis of the Arabidopsis RPS2 disease resistance gene and the corresponding pseudomonas syringae avrRpt2 avirulence gene.

Q03455	MSC2_YEAST	Probable zinc transporter MSC2	11058603	The yeast gene MSC2, a member of the cation diffusion facilitator family, affects the cellular distribution of zinc.

P83000	GSTE2_PSEUO	Glutathione S-transferase	11900268	Occurence and properties of glutathione S-transferases in phenol- degrading Pseudomonas strains.

O44514	PMK3_CAEEL	Mitogen-activated protein kinase pmk-3	11703092	Isolation and characterization of pmk-(1-3): three p38 homologs in Caenorhabditis elegans.

Q9FVC1	SVP_ARATH	MADS-box protein SVP	10758486	Molecular cloning of SVP: a negative regulator of the floral transition in Arabidopsis.

P60165	KA112_PARVI	Potassium channel toxin alpha-KTx 11.2	10542442	A unified nomenclature for short-chain peptides isolated from scorpion venoms: alpha-KTx molecular subfamilies.

P48581	RAD17_YEAST	DNA damage checkpoint control protein RAD17	9891048	Role of a complex containing Rad17, Mec3, and Ddc1 in the yeast DNA damage checkpoint pathway.

Q6DFV1	CNDG2_MOUSE	Condensin-2 complex subunit G2	14729962	More than blood, a novel gene required for mammalian postimplantation development.

P34995	PE2R1_HUMAN	Prostaglandin E2 receptor EP1 subtype	8253813	Cloning and expression of a cDNA for the human prostaglandin E receptor EP1 subtype.

Q02447	SP3_HUMAN	Transcription factor Sp3	9278495	Sp3 is a transcriptional activator of the human alpha2(I) collagen gene.

P41948	MEP2_YEAST	Ammonium transporter MEP2	9234685	A family of ammonium transporters in Saccharomyces cerevisiae.

P24008	S5A1_RAT	3-oxo-5-alpha-steroid 4-dehydrogenase 1	2476440	Expression cloning and regulation of steroid 5 alpha-reductase, an enzyme essential for male sexual differentiation.

P0A7A7	PLSB_ECOLI	Glycerol-3-phosphate acyltransferase	6251087	Membrane phospholipid synthesis in Escherichia coli. Cloning of a structural gene (plsB) of the sn-glycerol-3-phosphate acyl/transferase.

Q0KI50	DMDD_DROME	Dystrophin, isoform D	16399704	Dystrophin is required for appropriate retrograde control of neurotransmitter release at the Drosophila neuromuscular junction.

Q9NZN4	EHD2_HUMAN	EH domain-containing protein 2	10673336	EHD2, EHD3, and EHD4 encode novel members of a highly conserved family of EH domain-containing proteins.

Q8WXH0	SYNE2_HUMAN	Nesprin-2	18396275	Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness.

O13023	HHEX_XENLA	Hematopoietically-expressed homeobox protein hhex	9376326	The XHex homeobox gene is expressed during development of the vascular endothelium: overexpression leads to an increase in vascular endothelial cell number.

Q64MA3	GENL1_ORYSJ	Flap endonuclease GEN-like 1	15792960	RNAi-mediated silencing of OsGEN-L (OsGEN-like), a new member of the RAD2/XPG nuclease family, causes male sterility by defect of microspore development in rice.

Q13202	DUS8_HUMAN	Dual specificity protein phosphatase 8	7561881	hVH-5: a protein tyrosine phosphatase abundant in brain that inactivates mitogen-activated protein kinase.

P60484	PTEN_HUMAN	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	9616126	Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN.

O14514	BAI1_HUMAN	Brain-specific angiogenesis inhibitor 1	10343108	Identification of BAIAP2 (BAI-associated protein 2), a novel human homologue of hamster IRSp53, whose SH3 domain interacts with the cytoplasmic domain of BAI1.

Q9UUG2	YFT6_SCHPO	Uncharacterized leucine-rich repeat-containing protein C926.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q02981	YP109_YEAST	ABC1 family protein YPL109C, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q9ZSA4	CDPKR_ARATH	Calcium-dependent protein kinase 27	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

Q93WP8	HSYA_TOBAC	Hydroxyproline-rich systemin A	11459063	Production of multiple plant hormones from a single polyprotein precursor.

Q03327	UGO1_YEAST	Mitochondrial fusion and transport protein UGO1	15087460	Ugo1p links the Fzo1p and Mgm1p GTPases for mitochondrial fusion.

Q9NXA8	SIRT5_HUMAN	NAD-dependent deacetylase sirtuin-5	16079181	Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins.

Q13573	SNW1_HUMAN	SNW domain-containing protein 1	9569025	The Ski oncoprotein interacts with Skip, the human homolog of Drosophila Bx42.

O94355	RTX2_SCHPO	Transcriptional regulatory protein rxt2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q16584	M3K11_HUMAN	Mitogen-activated protein kinase kinase kinase 11	9829970	Dimerization via tandem leucine zippers is essential for the activation of the mitogen-activated protein kinase kinase kinase, MLK- 3.

Q940Y5	PIN7_ARATH	Auxin efflux carrier component 7	14614497	Efflux-dependent auxin gradients establish the apical-basal axis of Arabidopsis.

Q13485	SMAD4_HUMAN	Mothers against decapentaplegic homolog 4	17099224	Potentiation of Smad-mediated transcriptional activation by the RNA- binding protein RBPMS.

Q8IS44	DRD2L_DROME	Dopamine D2-like receptor	12391323	A Drosophila dopamine 2-like receptor: molecular characterization and identification of multiple alternatively spliced variants.

Q9SMN1	UMP8_ARATH	Uncharacterized protein At3g48680, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q91YJ3	THYN1_MOUSE	Thymocyte nuclear protein 1	14601557	Anti-IgM-induced down-regulation of nuclear Thy28 protein expression in Ramos B lymphoma cells.

P06126	CD1A_HUMAN	T-cell surface glycoprotein CD1a	2447586	Structure and expression of the human thymocyte antigens CD1a, CD1b, and CD1c.

P20294	CNTF_RAT	Ciliary neurotrophic factor	2594085	Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor.

Q09750	PST1_SCHPO	Paired amphipathic helix protein pst1	10022921	A new member of the Sin3 family of corepressors is essential for cell viability and required for retroelement propagation in fission yeast.

Q54UI0	Y3989_DICDI	Uncharacterized transmembrane protein DDB_G0281067	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P32588	PUB1_YEAST	Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1	8413213	PUB1: a major yeast poly(A)+ RNA-binding protein.

Q7YU29	DMDE_DROME	Dystrophin, isoform E	16399704	Dystrophin is required for appropriate retrograde control of neurotransmitter release at the Drosophila neuromuscular junction.

Q08970	MMT2_YEAST	Mitochondrial metal transporter 2	9353309	Characterization of two homologous yeast genes that encode mitochondrial iron transporters.

P11286	YIAB_ECOLI	Inner membrane protein yiaB	11867724	Rapid topology mapping of Escherichia coli inner-membrane proteins by prediction and PhoA/GFP fusion analysis.

P41046	CORTO_DROME	Centrosomal and chromosomal factor	12771214	The Drosophila Corto protein interacts with Polycomb-group proteins and the GAGA factor.

P35030	TRY3_HUMAN	Trypsin-3	8294000	Cloning of the cDNA encoding human brain trypsinogen and characterization of its product.

Q9H2E6	SEM6A_HUMAN	Semaphorin-6A	10993894	The orthologous human and murine semaphorin 6A-1 proteins (SEMA6A- 1/Sema6A-1) bind to the enabled/vasodilator-stimulated phosphoprotein- like protein (EVL) via a novel carboxyl-terminal zyxin-like domain.

O59810	YJVE_SCHPO	KH domain-containing protein C550.14	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q08673	SRL1_YEAST	Cell wall protein SRL1	11935221	Sequence-based approach for identification of cell wall proteins in Saccharomyces cerevisiae.

Q9SU56	GLDH_ARATH	L-galactono-1,4-lactone dehydrogenase, mitochondrial	18190525	L-galactono-gamma-lactone dehydrogenase from Arabidopsis thaliana, a flavoprotein involved in vitamin C biosynthesis.

Q62318	TIF1B_MOUSE	Transcription intermediary factor 1-beta	8978696	A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors.

P87058	LAH1_SCHPO	La protein homolog	9404894	The La protein in Schizosaccharomyces pombe: a conserved yet dispensable phosphoprotein that functions in tRNA maturation.

Q8UUZ1	MB212_DANRE	Protein mab-21-like 2	15183718	Zebrafish rx3 and mab21l2 are required during eye morphogenesis.

Q86SQ6	GP123_HUMAN	Probable G-protein coupled receptor 123	12565841	There exist at least 30 human G-protein-coupled receptors with long Ser/Thr-rich N-termini.

Q9Y2U5	M3K2_HUMAN	Mitogen-activated protein kinase kinase kinase 2	17906693	Negative regulation of MEKK1/2 signaling by serine-threonine kinase 38 (STK38).

Q5XPJ9	SCAR2_ARATH	Protein SCAR2	16006582	IRREGULAR TRICHOME BRANCH1 in Arabidopsis encodes a plant homolog of the actin-related protein2/3 complex activator Scar/WAVE that regulates actin and microtubule organization.

P22288	GCH1_RAT	GTP cyclohydrolase 1	11818540	Crystal structure of the stimulatory complex of GTP cyclohydrolase I and its feedback regulatory protein GFRP.

P38358	VBA2_YEAST	Vacuolar basic amino acid transporter 2	15572352	A family of basic amino acid transporters of the vacuolar membrane from Saccharomyces cerevisiae.

O35613	DAXX_MOUSE	Death domain-associated protein 6	11034606	FIST/HIPK3: a Fas/FADD-interacting serine/threonine kinase that induces FADD phosphorylation and inhibits Fas-mediated Jun NH2- terminal kinase activation.

O74441	YJEB_SCHPO	Uncharacterized choline transporter-like protein C1682.11c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P83221	PPIB_STRAT	Peptidyl-prolyl cis-trans isomerase cyp18	10400660	Purification, characterization, and role of nucleases and serine proteases in Streptomyces differentiation. Analogies with the biochemical processes described in late steps of eukaryotic apoptosis.

O95182	NDUA7_HUMAN	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

P0AAX8	YBIS_ECOLI	Probable L,D-transpeptidase YbiS	18456808	Identification of the L,D-transpeptidases for peptidoglycan cross- linking in Escherichia coli.

Q7LKX0	ELOH2_SCHPO	Putative elongation of fatty acids protein 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P43618	CNN1_YEAST	Kinetochore-associated protein CNN1	14633972	Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes.

O75083	WDR1_HUMAN	WD repeat-containing protein 1	10036186	A gene upregulated in the acoustically damaged chick basilar papilla encodes a novel WD40 repeat protein.

Q9QZU7	BODG_RAT	Gamma-butyrobetaine dioxygenase	10526231	Molecular cloning and characterization of the cDNA encoding the rat liver gamma-butyrobetaine hydroxylase.

Q9Z2Y1	TIM_RAT	Protein timeless homolog	10963667	A role for Timeless in epithelial morphogenesis during kidney development.

P32038	CFAD_RAT	Complement factor D	1953671	Purification and partial characterization of rat factor D.

Q9MA41	CTL1_ARATH	Chitinase-like protein 1	17156413	Arabidopsis hot2 encodes an endochitinase-like protein that is essential for tolerance to heat, salt and drought stresses.

Q04437	KU80_YEAST	ATP-dependent DNA helicase II subunit 2	16166630	The DNA repair protein yKu80 regulates the function of recombination enhancer during yeast mating type switching.

Q9VF26	SPNE_DROME	Probable ATP-dependent RNA helicase spindle-E	12154120	RNAi is activated during Drosophila oocyte maturation in a manner dependent on aubergine and spindle-E.

Q9P035	HACD3_HUMAN	3-hydroxyacyl-CoA dehydratase 3	10747961	B-ind1, a novel mediator of Rac1 signaling cloned from sodium butyrate-treated fibroblasts.

Q9Z325	DPM2_RAT	Dolichol phosphate-mannose biosynthesis regulatory protein	9724629	DPM2 regulates biosynthesis of dolichol phosphate-mannose in mammalian cells: correct subcellular localization and stabilization of DPM1, and binding of dolichol phosphate.

Q9UTQ5	YL39_SCHPO	Uncharacterized J domain-containing protein C1071.09c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P63032	RHES_MOUSE	GTP-binding protein Rhes	15199135	Rhes is involved in striatal function.

A2ARV4	LRP2_MOUSE	Low-density lipoprotein receptor-related protein 2	10766831	Megalin acts in concert with cubilin to mediate endocytosis of high density lipoproteins.

Q03532	HAS1_YEAST	ATP-dependent RNA helicase HAS1	15242642	Exploration of essential gene functions via titratable promoter alleles.

Q09147	FGFR2_DROME	Fibroblast growth factor receptor homolog 2	1849109	The Drosophila FGF-R homolog is expressed in the embryonic tracheal system and appears to be required for directed tracheal cell extension.

O00206	TLR4_HUMAN	Toll-like receptor 4	19252480	The structural basis of lipopolysaccharide recognition by the TLR4- MD-2 complex.

Q01469	FABP5_HUMAN	Fatty acid-binding protein, epidermal	8092987	Purification and characterization of the human epidermal fatty acid- binding protein: localization during epidermal cell differentiation in vivo and in vitro.

Q08058	COQ10_YEAST	Coenzyme Q-binding protein COQ10, mitochondrial	16230336	The Saccharomyces cerevisiae COQ10 gene encodes a START domain protein required for function of coenzyme Q in respiration.

P85258	CTX17_LACTA	M-zodatoxin-Lt8f	18215128	Cyto-insectotoxins, a novel class of cytolytic and insecticidal peptides from spider venom.

Q13111	CAF1A_HUMAN	Chromatin assembly factor 1 subunit A	12837248	The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome.

O95838	GLP2R_HUMAN	Glucagon-like peptide 2 receptor	9990065	Prototypic G protein-coupled receptor for the intestinotrophic factor glucagon-like peptide 2.

Q08509	EPS8_MOUSE	Epidermal growth factor receptor kinase substrate 8	19528316	Structure of human lanthionine synthetase C-like protein 1 and its interaction with Eps8 and glutathione.

Q09028	RBBP4_HUMAN	Histone-binding protein RBBP4	7503932	Dual retinoblastoma-binding proteins with properties related to a negative regulator of ras in yeast.

Q02796	LGE1_YEAST	Transcriptional regulatory protein LGE1	14562095	Global analysis of protein localization in budding yeast.

O75688	PPM1B_HUMAN	Protein phosphatase 1B	9684878	The cloning expression and tissue distribution of human PP2Cbeta.

P13498	CY24A_HUMAN	Cytochrome b-245 light chain	1763037	Point mutation in the cytoplasmic domain of the neutrophil p22-phox cytochrome b subunit is associated with a nonfunctional NADPH oxidase and chronic granulomatous disease.

O74350	YNOA_SCHPO	Bromodomain-containing protein C21D10.10	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q96D31	CRCM1_HUMAN	Calcium release-activated calcium channel protein 1	16807233	Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1.

Q16795	NDUA9_HUMAN	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

Q04439	MYO5_YEAST	Myosin-5	12391157	Saccharomyces cerevisiae Bzz1p is implicated with type I myosins in actin patch polarization and is able to recruit actin-polymerizing machinery in vitro.

Q9USM3	SFH1_SCHPO	Chromatin structure-remodeling complex subunit sfh1	14655046	Two-hybrid search for proteins that interact with Sad1 and Kms1, two membrane-bound components of the spindle pole body in fission yeast.

Q9EQG6	KDIS_RAT	Kinase D-interacting substrate of 220 kDa	11150334	An evolutionarily conserved transmembrane protein that is a novel downstream target of neurotrophin and ephrin receptors.

P31040	DHSA_HUMAN	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	19628817	SDH5, a gene required for flavination of succinate dehydrogenase, is mutated in paraganglioma.

Q5XFW6	WDR6_RAT	WD repeat-containing protein 6	17720279	Identification and characterization of an insulin receptor substrate 4-interacting protein in rat brain: implications for longevity.

Q6NN85	SSH_DROME	Protein phosphatase Slingshot	11832213	Control of actin reorganization by Slingshot, a family of phosphatases that dephosphorylate ADF/cofilin.

P20339	RAB5A_HUMAN	Ras-related protein Rab-5A	16034420	Structural basis of family-wide Rab GTPase recognition by rabenosyn- 5.

O94737	MAPK1_PNECA	Mitogen-activated protein kinase 1	10564487	Mitogen-activated protein kinase Mkp1 of Pneumocystis carinii complements the slt2Delta defect in the cell integrity pathway of Saccharomyces cerevisiae.

Q9FYE1	MCA9_ARATH	Metacaspase-9	17028019	Serpin1 of Arabidopsis thaliana is a suicide inhibitor for metacaspase 9.

Q18581	ACN1_CAEEL	Inactive angiotensin-converting enzyme-related protein	14559923	An essential role in molting and morphogenesis of Caenorhabditis elegans for ACN-1, a novel member of the angiotensin-converting enzyme family that lacks a metallopeptidase active site.

P26599	PTBP1_HUMAN	Polypyrimidine tract-binding protein 1	1641332	hnRNP I, the polypyrimidine tract-binding protein: distinct nuclear localization and association with hnRNAs.

P54274	TERF1_HUMAN	Telomeric repeat-binding factor 1	9391075	Characterization and cell cycle regulation of the related human telomeric proteins Pin2 and TRF1 suggest a role in mitosis.

Q9M7X9	CITRX_ARATH	Thioredoxin-like protein CITRX, chloroplastic	15028209	The Arabidopsis thaliana chloroplast proteome reveals pathway abundance and novel protein functions.

Q9FE25	MYB75_ARATH	Transcription factor MYB75	15361138	Comprehensive identification of Arabidopsis thaliana MYB transcription factors interacting with R/B-like BHLH proteins.

Q4JL91	IPPK_DANRE	Inositol-pentakisphosphate 2-kinase	15992547	Inositol polyphosphates regulate zebrafish left-right asymmetry.

P40020	FIR1_YEAST	Factor interacting with REF2	9196079	RNA binding analysis of yeast REF2 and its two-hybrid interaction with a new gene product, FIR1.

Q9VNS0	MAEL_DROME	Protein maelstrom	17428915	Unique germ-line organelle, nuage, functions to repress selfish genetic elements in Drosophila melanogaster.

Q9VWR5	CP306_DROME	Cytochrome P450 306a1	15350618	Phantom encodes the 25-hydroxylase of Drosophila melanogaster and Bombyx mori: a P450 enzyme critical in ecdysone biosynthesis.

P41682	ADH7_RAT	Alcohol dehydrogenase class 4 mu/sigma chain	10829036	Molecular basis for differential substrate specificity in class IV alcohol dehydrogenases: a conserved function in retinoid metabolism but not in ethanol oxidation.

Q8L5Y6	CAND1_ARATH	Cullin-associated NEDD8-dissociated protein 1	16943276	The HVE/CAND1 gene is required for the early patterning of leaf venation in Arabidopsis.

O35568	FBLN3_RAT	EGF-containing fibulin-like extracellular matrix protein 1	9268694	Interaction of DA41, a DAN-binding protein, with the epidermal growth factor-like protein, S(1-5).

O88751	CABP1_RAT	Calcium-binding protein 1	11865310	Differential modulation of Ca(v)2.1 channels by calmodulin and Ca2+- binding protein 1.

P79088	SC61A_SCHPO	Protein transport protein sec61 subunit alpha	9427389	Cloning of SEC61 homologues from Schizosaccharomyces pombe and Yarrowia lipolytica reveals the extent of functional conservation within this core component of the ER translocation machinery.

P40577	MND2_YEAST	Anaphase-promoting complex subunit MND2	12609981	Mnd2 and Swm1 are core subunits of the Saccharomyces cerevisiae anaphase-promoting complex.

P24343	HXD12_CHICK	Homeobox protein Hox-D12	11036080	A set of Hox proteins interact with the Maf oncoprotein to inhibit its DNA binding, transactivation, and transforming activities.

P40032	TPA1_YEAST	PKHD-type hydroxylase TPA1	16809762	Tpa1p is part of an mRNP complex that influences translation termination, mRNA deadenylation, and mRNA turnover in Saccharomyces cerevisiae.

P89105	CTR9_YEAST	RNA polymerase-associated protein CTR9	11884586	Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex.

Q9QXQ0	ACTN4_RAT	Alpha-actinin-4	10673389	BERP, a novel ring finger protein, binds to alpha-actinin-4.

Q9U1S7	PKD2_CAEEL	Polycystin-2	11553327	The Caenorhabditis elegans autosomal dominant polycystic kidney disease gene homologs lov-1 and pkd-2 act in the same pathway.

Q9LZM8	BLH9_ARATH	BEL1-like homeodomain protein 9	16741748	Arabidopsis inflorescence architecture requires the activities of KNOX-BELL homeodomain heterodimers.

P43609	RSC8_YEAST	Chromatin structure-remodeling complex protein RSC8	9685490	Direct interaction between Rsc6 and Rsc8/Swh3, two proteins that are conserved in SWI/SNF-related complexes.

P23522	GARL_ECOLI	5-keto-4-deoxy-D-glucarate aldolase	9772162	Evolution of enzymatic activities in the enolase superfamily: characterization of the (D)-glucarate/galactarate catabolic pathway in Escherichia coli.

Q13614	MTMR2_HUMAN	Myotubularin-related protein 2	9736772	Characterization of the myotubularin dual specificity phosphatase gene family from yeast to human.

Q9WU56	TRUA_MOUSE	tRNA pseudouridine synthase A, mitochondrial	15327771	Regulation of nuclear receptor activity by a pseudouridine synthase through posttranscriptional modification of steroid receptor RNA activator.

P48785	PRH_ARATH	Pathogenesis-related homeodomain protein	9351248	Developmental and auxin-induced expression of the Arabidopsis prha homeobox gene.

P25093	FAAA_RAT	Fumarylacetoacetase	1916290	Cloning and expression analysis of a cDNA encoding fumarylacetoacetate hydrolase: post-transcriptional modulation in rat liver and kidney.

Q09948	RSC4_SCHPO	Chromatin structure-remodeling complex subunit rsc4	18622392	Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast.

P69425	TATB_ECOLI	Sec-independent protein translocase protein tatB	9546395	A novel and ubiquitous system for membrane targeting and secretion of cofactor-containing proteins.

O01346	EGH_DROME	Beta-1,4-mannosyltransferase egh	12454022	Drosophila egghead encodes a beta 1,4-mannosyltransferase predicted to form the immediate precursor glycosphingolipid substrate for brainiac.

Q8K4T1	SIA8F_MOUSE	Alpha-2,8-sialyltransferase 8F	11980897	Molecular cloning and expression of a sixth type of alpha 2,8- sialyltransferase (ST8Sia VI) that sialylates O-glycans.

Q9H0M0	WWP1_HUMAN	NEDD4-like E3 ubiquitin-protein ligase WWP1	9169421	Identification of novel human WW domain-containing proteins by cloning of ligand targets.

Q9ZP16	CRK11_ARATH	Cysteine-rich receptor-like protein kinase 11	10377997	Characterization of an Arabidopsis thaliana receptor-like protein kinase gene activated by oxidative stress and pathogen attack.

Q12527	ATG11_YEAST	Autophagy-related protein 11	11309418	Cvt9/Gsa9 functions in sequestering selective cytosolic cargo destined for the vacuole.

O75899	GABR2_HUMAN	Gamma-aminobutyric acid type B receptor subunit 2	10328880	Molecular identification of the human GABABR2: cell surface expression and coupling to adenylyl cyclase in the absence of GABABR1.

P83571	RUVB2_DANRE	RuvB-like 2	12464178	Reptin and pontin antagonistically regulate heart growth in zebrafish embryos.

P13864	DNMT1_MOUSE	DNA (cytosine-5)-methyltransferase 1	15550930	Replication-independent chromatin loading of Dnmt1 during G2 and M phases.

Q9UHI7	S23A1_HUMAN	Solute carrier family 23 member 1	9804989	Molecular characterization of two novel transporters from human and mouse kidney and from LLC-PK1 cells reveals a novel conserved family that is homologous to bacterial and Aspergillus nucleobase transporters.

Q6DRP4	CCM2_DANRE	Malcavernin	16873582	santa and valentine pattern concentric growth of cardiac myocardium in the zebrafish.

Q67Y93	KRP1_ARATH	Cyclin-dependent kinase inhibitor 1	9753775	ICK1, a cyclin-dependent protein kinase inhibitor from Arabidopsis thaliana interacts with both Cdc2a and CycD3, and its expression is induced by abscisic acid.

Q01454	CTF4_YEAST	DNA polymerase alpha-binding protein	1448101	Evidence that POB1, a Saccharomyces cerevisiae protein that binds to DNA polymerase alpha, acts in DNA metabolism in vivo.

P46969	RPE_YEAST	Ribulose-phosphate 3-epimerase	8929392	Cloning and characterization of the first two genes of the non- oxidative part of the Saccharomyces cerevisiae pentose-phosphate pathway.

Q9SFG0	STP6_ARATH	Sugar transport protein 6	12529516	AtSTP6, a new pollen-specific H(+)-monosaccharide symporter from Arabidopsis.

O94664	MU166_SCHPO	Meiotically up-regulated gene 166 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O81829	GH35_ARATH	Indole-3-acetic acid-amido synthetase GH3.5	15659623	Characterization of an Arabidopsis enzyme family that conjugates amino acids to indole-3-acetic acid.

Q8VHC5	CABP4_MOUSE	Calcium-binding protein 4	16249514	A critical role of CaBP4 in the cone synapse.

Q16531	DDB1_HUMAN	DNA damage-binding protein 1	12732143	The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage.

Q9FRV4	NAC54_ARATH	Protein CUP-SHAPED COTYLEDON 1	17287247	Redundancy and specialization among plant microRNAs: role of the MIR164 family in developmental robustness.

Q9UJU5	FOXD3_HUMAN	Forkhead box protein D3	11891324	The embryonic stem cell transcription factors Oct-4 and FoxD3 interact to regulate endodermal-specific promoter expression.

Q10573	LIN25_CAEEL	Protein lin-25	3996896	Identification and characterization of 22 genes that affect the vulval cell lineages of the nematode Caenorhabditis elegans.

P14415	AT1B2_HUMAN	Sodium/potassium-transporting ATPase subunit beta-2	2538450	Identification of a putative isoform of the Na,K-ATPase beta subunit. Primary structure and tissue-specific expression.

P49137	MAPK2_HUMAN	MAP kinase-activated protein kinase 2	8179591	The primary structure of a human MAP kinase activated protein kinase 2.

Q04201	CUE4_YEAST	CUE domain-containing protein CUE4	11914276	Subcellular localization of the yeast proteome.

Q9VLU5	WWOX_DROME	WW domain-containing oxidoreductase	16007179	FRA16D common chromosomal fragile site oxido-reductase (FOR/WWOX) protects against the effects of ionizing radiation in Drosophila.

Q03818	ATG16_YEAST	Autophagy protein 16	11689437	The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation.

Q9UK53	ING1_HUMAN	Inhibitor of growth protein 1	10866301	Genomic structure of the human ING1 gene and tumor-specific mutations detected in head and neck squamous cell carcinomas.

P34111	TFC3_YEAST	Transcription factor tau 138 kDa subunit	1279682	TFC3: gene encoding the B-block binding subunit of the yeast transcription factor IIIC.

Q99758	ABCA3_HUMAN	ATP-binding cassette sub-family A member 3	8706931	Primary structure of a novel ABC transporter with a chromosomal localization on the band encoding the multidrug resistance-associated protein.

P34708	TRA1_CAEEL	Sex-determining transformer protein 1	11124807	Direct protein-protein interaction between the intracellular domain of TRA-2 and the transcription factor TRA-1A modulates feminizing activity in C. elegans.

P40615	DKC1_RAT	H/ACA ribonucleoprotein complex subunit 4	7798307	NAP57, a mammalian nucleolar protein with a putative homolog in yeast and bacteria.

Q9R189	UN13D_RAT	Protein unc-13 homolog D	10861235	Definition of Munc13-homology-domains and characterization of a novel ubiquitously expressed Munc13-isoform.

Q8L4H0	WEE1_ARATH	Wee1-like protein kinase	16856985	Diverse phosphoregulatory mechanisms controlling cyclin-dependent kinase-activating kinases in Arabidopsis.

Q93Y32	BCAT1_ARATH	Branched-chain-amino-acid aminotransferase 1, mitochondrial	12068099	The branched-chain amino acid transaminase gene family in Arabidopsis encodes plastid and mitochondrial proteins.

Q13363	CTBP1_HUMAN	C-terminal-binding protein 1	15897867	Oligomerization of Evi-1 regulated by the PR domain contributes to recruitment of corepressor CtBP.

Q5RJI4	PKDCC_MOUSE	Protein kinase domain-containing protein, cytoplasmic	19097194	Short limbs, cleft palate, and delayed formation of flat proliferative chondrocytes in mice with targeted disruption of a putative protein kinase gene, Pkdcc (AW548124).

P77044	MHPC_ECOLI	2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase	15663941	Catalytic mechanism of C-C hydrolase MhpC from Escherichia coli: kinetic analysis of His263 and Ser110 site-directed mutants.

Q9LJZ5	UBC19_ARATH	Ubiquitin-conjugating enzyme E2 19	16339806	Genome analysis and functional characterization of the E2 and RING- type E3 ligase ubiquitination enzymes of Arabidopsis.

Q08471	MSA1_YEAST	G1-specific transcription factors activator MSA1	18160399	The SBF- and MBF-associated protein Msa1 is required for proper timing of G1-specific transcription in Saccharomyces cerevisiae.

Q9UTB2	SYSM_SCHPO	Seryl-tRNA synthetase, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q13685	AAMP_HUMAN	Angio-associated migratory cell protein	10329261	Angio-associated migratory cell protein is expressed as an extracellular protein by blood-vessel-associated mesenchymal cells.

Q9R1S9	MK_RAT	Midkine	11136554	Midkine is expressed early in rat fetal adrenal development.

Q9NRH2	SNRK_HUMAN	SNF-related serine/threonine-protein kinase	12234663	Cloning and characterization of human and mouse SNRK sucrose non- fermenting protein (SNF-1)-related kinases.

P32645	ISC10_YEAST	Meiosis-specific protein ISC10	8455558	Isolation and characterization of a yeast gene that is homologous with a meiosis-specific cDNA from a plant.

Q63327	MOBP_RAT	Myelin-associated oligodendrocyte basic protein	7989345	Cloning and expression of myelin-associated oligodendrocytic basic protein. A novel basic protein constituting the central nervous system myelin.

P70507	GRK4_RAT	G protein-coupled receptor kinase 4	9607785	Rat G protein-coupled receptor kinase GRK4: identification, functional expression, and differential tissue distribution of two splice variants.

Q9GSB0	CRTP1_DICDI	Crt homolog 1	15883156	Dictyostelium discoideum expresses a malaria chloroquine resistance mechanism upon transfection with mutant, but not wild-type, Plasmodium falciparum transporter PfCRT.

P01710	LV207_HUMAN	Ig lambda chain V-II region BO	5532228	Amino acid sequence of human lambda chains. 3. Tryptic peptides, chymotryptic peptides, and sequence of protein Bo.

O44185	FLP13_CAEEL	FMRFamide-like neuropeptides 13	11527423	Isolation and preliminary biological assessment of AADGAPLIRFamide and SVPGVLRFamide from Caenorhabditis elegans.

P49914	MTHFS_HUMAN	5-formyltetrahydrofolate cyclo-ligase	19738041	Structural basis for the inhibition of human 5,10- methenyltetrahydrofolate synthetase by N10-substituted folate analogues.

Q9EQ46	V1R40_MOUSE	Vomeronasal type-1 receptor 40	11116090	Sequence diversity and genomic organization of vomeronasal receptor genes in the mouse.

Q9FFI2	ATG5_ARATH	Autophagy protein 5	16040659	Autophagic nutrient recycling in Arabidopsis directed by the ATG8 and ATG12 conjugation pathways.

O75582	KS6A5_HUMAN	Ribosomal protein S6 kinase alpha-5	9687510	Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB.

P17411	CHBF_ECOLI	6-phospho-beta-glucosidase	9405618	Wild-type Escherichia coli grows on the chitin disaccharide, N,N'- diacetylchitobiose, by expressing the cel operon.

P24814	GRR1_YEAST	SCF E3 ubiquitin ligase complex F-box protein GRR1	9736614	The Cdc42p effector Gic2p is targeted for ubiquitin-dependent degradation by the SCFGrr1 complex.

P82715	PPD5_ARATH	PsbP domain-containing protein 5, chloroplastic	11719511	Proteome map of the chloroplast lumen of Arabidopsis thaliana.

Q09688	MU121_SCHPO	Meiotically up-regulated gene 121 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O94609	UBA1_SCHPO	Ubiquitin-activating enzyme E1 1	9168469	Isolation and molecular characterization of mRNA transport mutants in Schizosaccharomyces pombe.

Q17446	PMK1_CAEEL	Mitogen-activated protein kinase pmk-1	11703092	Isolation and characterization of pmk-(1-3): three p38 homologs in Caenorhabditis elegans.

Q86IV5	CTNA_DICDI	Countin-1	11090633	A precise group size in Dictyostelium is generated by a cell-counting factor modulating cell-cell adhesion.

Q07508	LUC7_YEAST	Protein LUC7	10500099	Luc7p, a novel yeast U1 snRNP protein with a role in 5' splice site recognition.

Q10473	GALT1_RAT	Polypeptide N-acetylgalactosaminyltransferase 1	12364335	The lectin domain of UDP-GalNAc:polypeptide N- acetylgalactosaminyltransferase 1 is involved in O-glycosylation of a polypeptide with multiple acceptor sites.

P53072	TAN1_YEAST	tRNA acetyltransferase TAN1	14562095	Global analysis of protein localization in budding yeast.

P62850	RS24_RAT	40S ribosomal protein S24	2335205	The primary structure of rat ribosomal protein S24.

Q91Y44	BRDT_MOUSE	Bromodomain testis-specific protein	12861021	Acetylation-dependent chromatin reorganization by BRDT, a testis- specific bromodomain-containing protein.

P13725	ONCM_HUMAN	Oncostatin-M	1542793	Oncostatin M as a potent mitogen for AIDS-Kaposi's sarcoma-derived cells.

Q9QYX7	PCLO_MOUSE	Protein piccolo	10508862	Aczonin, a 550-kd putative scaffolding protein of presynaptic active zones, shares homology regions with rim and bassoon and binds profilin.

P40361	YJH0_YEAST	Inactive deaminase YJL070C	14562095	Global analysis of protein localization in budding yeast.

P08539	GPA1_YEAST	Guanine nucleotide-binding protein alpha-1 subunit	8756677	Sst2, a negative regulator of pheromone signaling in the yeast Saccharomyces cerevisiae: Expression, localization, and genetic interaction and physical association with Gpa1 (the G-protein alpha subunit).

P32802	TMN1_YEAST	Transmembrane 9 superfamily member 1	8314797	Partial purification and characterization of early and late endosomes from yeast. Identification of four novel proteins.

P53919	NAF1_YEAST	H/ACA ribonucleoprotein complex non-core subunit NAF1	12228251	The Shq1p.Naf1p complex is required for box H/ACA small nucleolar ribonucleoprotein particle biogenesis.

Q9V4P1	ANLN_DROME	Actin-binding protein anillin	15380073	Terminal cytokinesis events uncovered after an RNAi screen.

P01014	OVALY_CHICK	Ovalbumin-related protein Y	16428832	Ovalbumin-related gene Y protein bears carbohydrate chains of the ovomucoid type.

Q8UW74	HE71A_XENLA	Transcription factor HES-7.1-A	15935340	Identification of target genes for the Xenopus Hes-related protein XHR1, a prepattern factor specifying the midbrain-hindbrain boundary.

Q9PT61	OTX5B_XENLA	Homeobox protein otx5-B	15347652	Conserved transcriptional activators of the Xenopus rhodopsin gene.

P06702	S10A9_HUMAN	Protein S100-A9	3313057	Two calcium-binding proteins in infiltrate macrophages of rheumatoid arthritis.

P84507	TX1_CERMR	Beta-theraphotoxin-Cm1a	16267209	Four novel tarantula toxins as selective modulators of voltage-gated sodium channel subtypes.

P41143	OPRD_HUMAN	Delta-type opioid receptor	15086532	Identification of a novel family of G protein-coupled receptor associated sorting proteins.

Q86VD9	PIGZ_HUMAN	GPI mannosyltransferase 4	15208306	Human Smp3p adds a fourth mannose to yeast and human glycosylphosphatidylinositol precursors in vivo.

Q16048	MCHL1_HUMAN	Putative pro-MCH-like protein 1	8326825	Isolation and characterization of the human melanin-concentrating hormone gene and a variant gene.

O14183	MU114_SCHPO	Meiotically up-regulated gene 114 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P47881	OR3A1_HUMAN	Olfactory receptor 3A1	8647456	Olfactory receptor-encoding genes and pseudogenes are expressed in humans.

O13819	YMR1_SCHPO	Probable phosphoinositide 3-phosphatase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q810B9	SLIK3_MOUSE	SLIT and NTRK-like protein 3	14550773	Identification and characterization of Slitrk, a novel neuronal transmembrane protein family controlling neurite outgrowth.

O14520	AQP7_HUMAN	Aquaporin-7	9405233	Molecular cloning and expression of a novel human aquaporin from adipose tissue with glycerol permeability.

P08949	NMB_HUMAN	Neuromedin-B	2458345	Molecular cloning of cDNAs encoding the human bombesin-like peptide neuromedin B. Chromosomal localization and comparison to cDNAs encoding its amphibian homolog ranatensin.

Q3THG9	AASD1_MOUSE	Alanyl-tRNA editing protein Aarsd1	18172502	Distinct domains of tRNA synthetase recognize the same base pair.

P48442	CASR_RAT	Extracellular calcium-sensing receptor	7724534	Calcium sensing receptor: molecular cloning in rat and localization to nerve terminals.

P07713	DECA_DROME	Protein decapentaplegic	9226445	DPP controls tracheal cell migration along the dorsoventral body axis of the Drosophila embryo.

Q08289	CACB2_HUMAN	Voltage-dependent L-type calcium channel subunit beta-2	17525370	Dominant negative suppression of Rad leads to QT prolongation and causes ventricular arrhythmias via modulation of L-type Ca2+ channels in the heart.

Q54U87	DHKA_DICDI	Hybrid signal transduction histidine kinase A	8670894	A two-component histidine kinase gene that functions in Dictyostelium development.

Q8N697	S15A4_HUMAN	Solute carrier family 15 member 4	11741232	Human proton/oligopeptide transporter (POT) genes: identification of putative human genes using bioinformatics.

P11597	CETP_HUMAN	Cholesteryl ester transfer protein	3600759	Cloning and sequencing of human cholesteryl ester transfer protein cDNA.

O60237	MYPT2_HUMAN	Protein phosphatase 1 regulatory subunit 12B	9570949	A new isoform of human myosin phosphatase targeting/regulatory subunit (MYPT2): cDNA cloning, tissue expression, and chromosomal mapping.

P49597	P2C56_ARATH	Protein phosphatase 2C 56	18298671	Nuclear localization of the mutant protein phosphatase abi1 is required for insensitivity towards ABA responses in Arabidopsis.

P14784	IL2RB_HUMAN	Interleukin-2 receptor subunit beta	2785715	Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.

Q9NPP4	NLRC4_HUMAN	NLR family CARD domain-containing protein 4	11374873	Human CARD12 is a novel CED4/Apaf-1 family member that induces apoptosis.

O94864	ST65G_HUMAN	STAGA complex 65 subunit gamma	10987294	A new tumor-rejection antigen recognized by cytotoxic T lymphocytes infiltrating into a lung adenocarcinoma.

Q14683	SMC1A_HUMAN	Structural maintenance of chromosomes protein 1A	11877377	SMC1 is a downstream effector in the ATM/NBS1 branch of the human S- phase checkpoint.

Q9JIX5	CHD8_RAT	Chromodomain-helicase-DNA-binding protein 8	16452319	Suppression of STAT3 activity by Duplin, which is a negative regulator of the Wnt signal.

P25746	HFLD_ECOLI	High frequency lysogenization protein hflD	11278968	Revisiting the lysogenization control of bacteriophage lambda. Identification and characterization of a new host component, HflD.

Q47129	FEAR_ECOLI	Transcriptional activator feaR	8631685	maoB, a gene that encodes a positive regulator of the monoamine oxidase gene (maoA) in Escherichia coli.

P14922	CYC8_YEAST	General transcriptional corepressor CYC8	9741624	The DNA replication and damage checkpoint pathways induce transcription by inhibition of the Crt1 repressor.

Q39128	KAT1_ARATH	Potassium channel KAT1	11042178	Guard cell inward K+ channel activity in Arabidopsis involves expression of the twin channel subunits KAT1 and KAT2.

Q09128	CP24A_RAT	1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	1991512	Cloning and expression of cDNA encoding 25-hydroxyvitamin D3 24- hydroxylase.

P40380	RUM1_SCHPO	Cyclin-dependent kinase inhibitor rum1	14970237	Requirement of the SCFPop1/Pop2 ubiquitin ligase for degradation of the fission yeast S phase cyclin Cig2.

Q9WV06	ANKR2_MOUSE	Ankyrin repeat domain-containing protein 2	12004005	Arpp, a new homolog of carp, is preferentially expressed in type 1 skeletal muscle fibers and is markedly induced by denervation.

O14215	PRI1_SCHPO	DNA primase small subunit	11027257	Analysis of fission yeast primase defines the checkpoint responses to aberrant S phase initiation.

Q61140	BCAR1_MOUSE	Breast cancer anti-estrogen resistance protein 1	7479864	Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas.

Q14207	NPAT_HUMAN	Protein NPAT	17974976	The HiNF-P/p220NPAT cell cycle signaling pathway controls nonhistone target genes.

Q90VV1	HES4B_XENLA	Transcription factor HES-4-B	18721802	Hairy2-Id3 interactions play an essential role in Xenopus neural crest progenitor specification.

Q9ZVD0	SRRT_ARATH	Serrate RNA effector molecule	17442570	Identification of nuclear dicing bodies containing proteins for microRNA biogenesis in living Arabidopsis plants.

Q13627	DYR1A_HUMAN	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	8769099	Cloning of a human homolog of the Drosophila minibrain/rat Dyrk gene from 'the Down syndrome critical region' of chromosome 21.

Q5ZKN5	FA53A_CHICK	Protein FAM53A	11984880	Isolation of DNTNP, which encodes a potential nuclear protein that is expressed in the developing, dorsal neural tube.

Q14435	GALT3_HUMAN	Polypeptide N-acetylgalactosaminyltransferase 3	9295285	Substrate specificities of three members of the human UDP-N-acetyl- alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase family, GalNAc-T1, -T2, and -T3.

P07713	DECA_DROME	Protein decapentaplegic	8252627	The TGF beta homolog dpp and the segment polarity gene hedgehog are required for propagation of a morphogenetic wave in the Drosophila retina.

Q9UHL9	GT2D1_HUMAN	General transcription factor II-I repeat domain-containing protein 1	9774679	Identification of a novel slow-muscle-fiber enhancer binding protein, MUSTRD1.

Q05515	SVF1_YEAST	Survival factor 1	16034825	Svf1 inhibits reactive oxygen species generation and promotes survival under conditions of oxidative stress in Saccharomyces cerevisiae.

P42743	UBC15_ARATH	Ubiquitin-conjugating enzyme 15	16339806	Genome analysis and functional characterization of the E2 and RING- type E3 ligase ubiquitination enzymes of Arabidopsis.

Q8X168	GANA_ASPNG	Arabinogalactan endo-1,4-beta-galactosidase A	12383257	Endogalactanase A from Aspergillus niger is specifically induced on L-arabinose and galacturonic acid and plays an important role in the degradation of pectic hairy regions.

O74854	POF6_SCHPO	F-box protein pof6	15147268	Molecular interactions of fission yeast Skp1 and its role in the DNA damage checkpoint.

O08726	GALR2_RAT	Galanin receptor type 2	9305929	Expression cloning of a rat hypothalamic galanin receptor coupled to phosphoinositide turnover.

Q62991	SCFD1_RAT	Sec1 family domain-containing protein 1	9195952	Cloning of a putative vesicle transport-related protein, RA410, from cultured rat astrocytes and its expression in ischemic rat brain.

Q9SHI7	UBC34_ARATH	Ubiquitin-conjugating enzyme E2 34	16339806	Genome analysis and functional characterization of the E2 and RING- type E3 ligase ubiquitination enzymes of Arabidopsis.

O17514	MES2_CAEEL	Histone-lysine N-methyltransferase mes-2	15380065	The MES-2/MES-3/MES-6 complex and regulation of histone H3 methylation in C. elegans.

Q79PF6	KAIA_SYNE7	Circadian clock protein kaiA	10064581	Physical interactions among circadian clock proteins KaiA, KaiB and KaiC in cyanobacteria.

P52478	UBC1_CAEEL	Ubiquitin-conjugating enzyme E2 1	7546294	Caenorhabditis elegans UBC-1, a ubiquitin-conjugating enzyme homologous to yeast RAD6/UBC2, contains a novel carboxy-terminal extension that is conserved in nematodes.

P42730	HS101_ARATH	Heat shock protein 101	7866032	An Arabidopsis heat shock protein complements a thermotolerance defect in yeast.

Q8BZN6	DOC10_MOUSE	Dedicator of cytokinesis protein 10	15710388	Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes.

P40722	SOPD_SALTY	Secreted effector protein sopD	15554961	The related effector proteins SopD and SopD2 from Salmonella enterica serovar Typhimurium contribute to virulence during systemic infection of mice.

Q9W5D4	POMT2_DROME	Protein O-mannosyl-transferase 2	16219785	The twisted gene encodes Drosophila protein O-mannosyltransferase 2 and genetically interacts with the rotated abdomen gene encoding Drosophila protein O-mannosyltransferase 1.

O76095	JTB_HUMAN	Protein JTB	10321732	JTB: a novel membrane protein gene at 1q21 rearranged in a jumping translocation.

O43526	KCNQ2_HUMAN	Potassium voltage-gated channel subfamily KQT member 2	9425895	A novel potassium channel gene, KCNQ2, is mutated in an inherited epilepsy of newborns.

P84040	H4_DROME	Histone H4	8690091	Identification and characterization of the Drosophila histone H4 replacement gene.

Q8W468	ARI8_ARATH	Probable E3 ubiquitin-protein ligase ARI8	15644464	Functional analysis of the RING-type ubiquitin ligase family of Arabidopsis.

Q9UP79	ATS8_HUMAN	A disintegrin and metalloproteinase with thrombospondin motifs 8	10438512	METH-1, a human ortholog of ADAMTS-1, and METH-2 are members of a new family of proteins with angio-inhibitory activity.

P39002	LCF3_YEAST	Long-chain-fatty-acid--CoA ligase 3	8206942	Biochemical studies of three Saccharomyces cerevisiae acyl-CoA synthetases, Faa1p, Faa2p, and Faa3p.

P41740	ANPRC_RAT	Atrial natriuretic peptide receptor 3	7911802	A single residue determines the distinct pharmacology of rat and human natriuretic peptide receptor-C.

P51792	CLCN3_RAT	H(+)/Cl(-) exchange transporter 3	10915634	Expression and canalicular localization of two isoforms of the ClC-3 chloride channel from rat hepatocytes.

Q05931	HSP7Q_YEAST	Heat shock protein SSQ1, mitochondrial	10779357	Role of the mitochondrial Hsp70s, Ssc1 and Ssq1, in the maturation of Yfh1.

P34161	YOX1_YEAST	Homeobox protein YOX1	12464633	Conserved homeodomain proteins interact with MADS box protein Mcm1 to restrict ECB-dependent transcription to the M/G1 phase of the cell cycle.

Q14894	CRYM_HUMAN	Mu-crystallin homolog	17242435	Crystal structure of human micro-crystallin complexed with NADPH.

P49598	P2C37_ARATH	Protein phosphatase 2C 37	16361522	The protein phosphatase AtPP2CA negatively regulates abscisic acid signal transduction in Arabidopsis, and effects of abh1 on AtPP2CA mRNA.

O77374	PF07_PLAF7	Uncharacterized protein PFC0810c	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

O60059	YG58_SCHPO	Pumilio domain-containing protein C56F2.08c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P47143	ADK_YEAST	Adenosine kinase	11223943	Role of adenosine kinase in Saccharomyces cerevisiae: identification of the ADO1 gene and study of the mutant phenotypes.

Q86UP6	CUZD1_HUMAN	CUB and zona pellucida-like domain-containing protein 1	15184879	Molecular cloning, characterization and isolation of novel spliced variants of the human ortholog of a rat estrogen-regulated membrane- associated protein, UO-44.

Q8WUM4	PDC6I_HUMAN	Programmed cell death 6-interacting protein	18256029	Identification of Alix-type and non-Alix-type ALG-2-binding sites in human phospholipid scramblase 3: differential binding to an alternatively spliced isoform and amino acid-substituted mutants.

Q99KG5	LSR_MOUSE	Lipolysis-stimulated lipoprotein receptor	15265030	Distribution of the lipolysis stimulated receptor in adult and embryonic murine tissues and lethality of LSR-/- embryos at 12.5 to 14.5 days of gestation.

P01906	DQA2_HUMAN	HLA class II histocompatibility antigen, DQ alpha 2 chain	3036828	Class II genes of the human major histocompatibility complex. Comparisons of the DQ and DX alpha and beta genes.

Q9FED2	HA22E_ARATH	HVA22-like protein e	12081371	AtHVA22 gene family in Arabidopsis: phylogenetic relationship, ABA and stress regulation, and tissue-specific expression.

P54657	CAD1_DICDI	Calcium-dependent cell adhesion molecule 1	17057715	Solution structures of the adhesion molecule DdCAD-1 reveal new insights into Ca(2+)-dependent cell-cell adhesion.

Q04272	VPS20_YEAST	Vacuolar protein sorting-associated protein 20	12194857	Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting.

Q99J87	DHX58_MOUSE	Probable ATP-dependent RNA helicase DHX58	11735219	The Stat3/5 locus encodes novel endoplasmic reticulum and helicase- like proteins that are preferentially expressed in normal and neoplastic mammary tissue.

Q9R080	GPSM1_RAT	G-protein-signaling modulator 1	10559191	Receptor-independent activators of heterotrimeric G-protein signaling pathways.

Q9GYU7	MED10_DROME	Mediator of RNA polymerase II transcription subunit 10	15477388	A high resolution protein interaction map of the yeast Mediator complex.

Q13438	OS9_HUMAN	Protein OS-9	19346256	Human OS-9, a lectin required for glycoprotein endoplasmic reticulum- associated degradation, recognizes mannose-trimmed N-glycans.

Q64331	MYO6_MOUSE	Myosin-VI	7493015	The mouse Snell's waltzer deafness gene encodes an unconventional myosin required for structural integrity of inner ear hair cells.

Q9Y705	ALP4_SCHPO	Spindle pole body component alp4	16111942	Hrs1p/Mcp6p on the meiotic SPB organizes astral microtubule arrays for oscillatory nuclear movement.

Q92574	TSC1_HUMAN	Hamartin	9580671	Interaction between hamartin and tuberin, the TSC1 and TSC2 gene products.

O75001	MCM7_SCHPO	DNA replication licensing factor mcm7	9366552	A globular complex formation by Nda1 and the other five members of the MCM protein family in fission yeast.

Q9H8V3	ECT2_HUMAN	Protein ECT2	16129829	MgcRacGAP controls the assembly of the contractile ring and the initiation of cytokinesis.

Q6Q2Z6	ACOT5_MOUSE	Acyl-coenzyme A thioesterase 5	15007068	Molecular cloning and characterization of two mouse peroxisome proliferator-activated receptor alpha (PPARalpha)-regulated peroxisomal acyl-CoA thioesterases.

P40416	ATM1_YEAST	Iron-sulfur clusters transporter ATM1, mitochondrial	7828591	An ABC transporter in the mitochondrial inner membrane is required for normal growth of yeast.

Q16549	PCSK7_HUMAN	Proprotein convertase subtilisin/kexin type 7	9341152	Biosynthesis, distinct post-translational modifications, and functional characterization of lymphoma proprotein convertase.

P30825	CTR1_HUMAN	High affinity cationic amino acid transporter 1	1348489	The human cationic amino acid transporter (ATRC1): physical and genetic mapping to 13q12-q14.

Q06506	RRP9_YEAST	Ribosomal RNA-processing protein 9	12068309	A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis.

Q15911	ZFHX3_HUMAN	Zinc finger homeobox protein 3	11312261	Positive and negative regulation of myogenic differentiation of C2C12 cells by isoforms of the multiple homeodomain zinc finger transcription factor ATBF1.

P32354	MCM10_YEAST	Minichromosome maintenance protein 10	16782870	Interaction between PCNA and diubiquitinated Mcm10 is essential for cell growth in budding yeast.

Q9Y5X1	SNX9_HUMAN	Sorting nexin-9	10531379	Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1.

Q7JXV9	VPS25_DROME	Vacuolar protein-sorting-associated protein 25	16256745	Tumor suppressor properties of the ESCRT-II complex component Vps25 in Drosophila.

P04147	PABP_YEAST	Polyadenylate-binding protein, cytoplasmic and nuclear	15769879	Yeast poly(A)-binding protein Pab1 shuttles between the nucleus and the cytoplasm and functions in mRNA export.

Q96T23	RSF1_HUMAN	Remodeling and spacing factor 1	11944984	HBXAP, a novel PHD-finger protein, possesses transcription repression activity.

O42261	IRX3_XENLA	Iroquois-class homeodomain protein irx-3	9427753	Xiro3 encodes a Xenopus homolog of the Drosophila Iroquois genes and functions in neural specification.

P31315	GSX1_MOUSE	GS homeobox 1	8589431	Gsh-1: a novel murine homeobox gene expressed in the central nervous system.

Q38845	2AAA_ARATH	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform	11161061	The Arabidopsis eer1 mutant has enhanced ethylene responses in the hypocotyl and stem.

Q9H0E9	BRD8_HUMAN	Bromodomain-containing protein 8	9368056	Isolation and characterization of a novel ligand-dependent thyroid hormone receptor-coactivating protein.

O14964	HGS_HUMAN	Hepatocyte growth factor-regulated tyrosine kinase substrate	9407053	Hrs is associated with STAM, a signal-transducing adaptor molecule. Its suppressive effect on cytokine-induced cell growth.

Q15415	RBY1F_HUMAN	RNA-binding motif protein, Y chromosome, family 1 member F/J	8269511	A Y chromosome gene family with RNA-binding protein homology: candidates for the azoospermia factor AZF controlling human spermatogenesis.

Q8LGD5	MKS1_ARATH	Protein MKS1	15990873	The MAP kinase substrate MKS1 is a regulator of plant defense responses.

P24534	EF1B_HUMAN	Elongation factor 1-beta	1886777	Nucleotide sequence of human elongation factor-1 beta cDNA.

Q680I0	ORTH5_ARATH	E3 ubiquitin-protein ligase ORTHRUS 5	18704160	Three SRA-domain methylcytosine-binding proteins cooperate to maintain global CpG methylation and epigenetic silencing in Arabidopsis.

Q54S20	MED13_DICDI	Mediator of RNA polymerase II transcription subunit 13	10651904	amiB, a novel gene required for the growth/differentiation transition in Dictyostelium.

P08172	ACM2_HUMAN	Muscarinic acetylcholine receptor M2	3443095	Distinct primary structures, ligand-binding properties and tissue- specific expression of four human muscarinic acetylcholine receptors.

Q38997	KIN10_ARATH	SNF1-related protein kinase catalytic subunit alpha KIN10	10220464	Regulatory interaction of PRL1 WD protein with Arabidopsis SNF1-like protein kinases.

Q9SF32	IQD1_ARATH	Protein IQ-DOMAIN 1	15960618	Arabidopsis IQD1, a novel calmodulin-binding nuclear protein, stimulates glucosinolate accumulation and plant defense.

P62995	TRA2B_HUMAN	Transformer-2 protein homolog beta	15169763	Distinct sequence motifs within the 68-kDa subunit of cleavage factor Im mediate RNA binding, protein-protein interactions, and subcellular localization.

P09152	NARG_ECOLI	Respiratory nitrate reductase 1 alpha chain	14725769	Architecture of NarGH reveals a structural classification of Mo- bisMGD enzymes.

P31381	FUN26_YEAST	Nucleoside transporter FUN26	10827169	Nucleoside transporter proteins of Saccharomyces cerevisiae. Demonstration of a transporter (FUI1) with high uridine selectivity in plasma membranes and a transporter (FUN26) with broad nucleoside selectivity in intracellular membranes.

Q8C4V4	FBXL3_MOUSE	F-box/LRR-repeat protein 3	17462724	Circadian mutant Overtime reveals F-box protein FBXL3 regulation of cryptochrome and period gene expression.

Q9SNC6	PUB13_ARATH	U-box domain-containing protein 13	14657406	A large complement of the predicted Arabidopsis ARM repeat proteins are members of the U-box E3 ubiquitin ligase family.

Q8WYA1	BMAL2_HUMAN	Aryl hydrocarbon receptor nuclear translocator-like protein 2	11018023	CLIF, a novel cycle-like factor, regulates the circadian oscillation of plasminogen activator inhibitor-1 gene expression.

Q792I0	LIN7C_RAT	Protein lin-7 homolog C	10362251	Isolation and characterization of mammalian homologues of Caenorhabditis elegans lin-7: localization at cell-cell junctions.

O43058	SEP1_SCHPO	Forkhead protein sep1	15509866	Fkh2p and Sep1p regulate mitotic gene transcription in fission yeast.

P46982	MNN5_YEAST	Alpha-1,2-mannosyltransferase MNN5	9756928	Identification of the MNN2 and MNN5 mannosyltransferases required for forming and extending the mannose branches of the outer chain mannans of Saccharomyces cerevisiae.

P17695	GLRX2_YEAST	Glutaredoxin-2, mitochondrial	12684511	Role of yeast glutaredoxins as glutathione S-transferases.

O13606	MEI4_SCHPO	Meiosis-specific transcription factor mei4	9528784	The Schizosaccharomyces pombe mei4+ gene encodes a meiosis-specific transcription factor containing a forkhead DNA-binding domain.

P40855	PEX19_HUMAN	Peroxisomal biogenesis factor 19	9339377	Genomic organization and molecular characterization of a gene encoding HsPXF, a human peroxisomal farnesylated protein.

Q91X43	SH319_MOUSE	SH3 domain-containing protein 19	12615363	Gene expression of Sh3d19, a novel adaptor protein with five Src homology 3 domains, in anagen mouse hair follicles.

Q9Z1B8	PHF1_MOUSE	PHD finger protein 1	11559747	CHMP1 is a novel nuclear matrix protein affecting chromatin structure and cell-cycle progression.

O75554	WBP4_HUMAN	WW domain-binding protein 4	19592703	Structure and function of the two tandem WW domains of the pre-mRNA splicing factor FBP21 (formin-binding protein 21).

Q6AT33	IAA19_ORYSJ	Auxin-responsive protein IAA19	16200395	Structure and expression analysis of early auxin-responsive Aux/IAA gene family in rice (Oryza sativa).

Q12265	KPR5_YEAST	Ribose-phosphate pyrophosphokinase 5	10212224	Genetic analysis and enzyme activity suggest the existence of more than one minimal functional unit capable of synthesizing phosphoribosyl pyrophosphate in Saccharomyces cerevisiae.

P38772	BCD1_YEAST	Box C/D snoRNA protein 1	14562095	Global analysis of protein localization in budding yeast.

P34217	PIN4_YEAST	RNA-binding protein PIN4	14562095	Global analysis of protein localization in budding yeast.

O14185	STG1_SCHPO	Transgelin	16256112	Stg1 is a novel SM22/transgelin-like actin-modulating protein in fission yeast.

Q7PLI2	NIPB_DROME	Nipped-B protein	15060134	Drosophila nipped-B protein supports sister chromatid cohesion and opposes the stromalin/Scc3 cohesion factor to facilitate long-range activation of the cut gene.

P01596	KV104_HUMAN	Ig kappa chain V-I region CAR	4216454	Primary structure of kappa light chain from a human myeloma protein.

Q869S5	DOKA_DICDI	Hybrid signal transduction protein dokA	8670893	The hybrid histidine kinase DokA is part of the osmotic response system of Dictyostelium.

P60709	ACTB_HUMAN	Actin, cytoplasmic 1	19377461	GlcNAcylation of a histone methyltransferase in retinoic-acid-induced granulopoiesis.

P36596	FDFT_SCHPO	Squalene synthase	17016471	Repression of ergosterol level during oxidative stress by fission yeast F-box protein Pof14 independently of SCF.

Q01574	ACS1_YEAST	Acetyl-coenzyme A synthetase 1	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P38850	RT107_YEAST	Regulator of Ty1 transposition protein 107	14562095	Global analysis of protein localization in budding yeast.

P76016	DHAR_ECOLI	PTS-dependent dihydroxyacetone kinase operon regulatory protein	15616579	Escherichia coli dihydroxyacetone kinase controls gene expression by binding to transcription factor DhaR.

Q21441	KI26L_CAEEL	Kinesin-like protein vab-8	8625818	The C. elegans gene vab-8 guides posteriorly directed axon outgrowth and cell migration.

P50897	PPT1_HUMAN	Palmitoyl-protein thioesterase 1	7637805	Mutations in the palmitoyl protein thioesterase gene causing infantile neuronal ceroid lipofuscinosis.

Q14137	BOP1_HUMAN	Ribosome biogenesis protein BOP1	16738141	Dominant-negative Pes1 mutants inhibit ribosomal RNA processing and cell proliferation via incorporation into the PeBoW-complex.

P09734	TBA3_YEAST	Tubulin alpha-3 chain	11266443	Cortical Num1p interacts with the dynein intermediate chain Pac11p and cytoplasmic microtubules in budding yeast.

P40030	ERG28_YEAST	Ergosterol biosynthetic protein 28	15522820	The ERG28-encoded protein, Erg28p, interacts with both the sterol C-4 demethylation enzyme complex as well as the late biosynthetic protein, the C-24 sterol methyltransferase (Erg6p).

Q9P7W9	RNP1_SCHPO	Probable ribonuclease P protein subunit 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P50488	DAF4_CAEEL	Cell surface receptor daf-4	10887089	A Caenorhabditis elegans type I TGF beta receptor can function in the absence of type II kinase to promote larval development.

Q8TDU6	GPBAR_HUMAN	G-protein coupled bile acid receptor 1	12524422	A G protein-coupled receptor responsive to bile acids.

P87108	TIM10_YEAST	Mitochondrial import inner membrane translocase subunit TIM10	9889188	Tim9, a new component of the TIM22.54 translocase in mitochondria.

P54318	LIPR2_RAT	Pancreatic lipase-related protein 2	8203536	Rat pancreatic lipase and two related proteins: enzymatic properties and mRNA expression during development.

Q9D1N2	HDBP1_MOUSE	Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1	17403372	Glycosylphosphatidylinositol-anchored high-density lipoprotein- binding protein 1 plays a critical role in the lipolytic processing of chylomicrons.

P42128	FOXK1_MOUSE	Forkhead box protein K1	9271401	Transient expression of a winged-helix protein, MNF-beta, during myogenesis.

P31000	VIME_RAT	Vimentin	1540169	Differential expression of vimentin in rat prostatic tumors.

Q05902	ECM38_YEAST	Gamma-glutamyltransferase	11672438	Gamma-glutamyl transpeptidase in the yeast Saccharomyces cerevisiae and its role in the vacuolar transport and metabolism of glutathione.

P28072	PSB6_HUMAN	Proteasome subunit beta type-6	8066462	cDNA cloning and interferon gamma down-regulation of proteasomal subunits X and Y.

P10124	SRGN_HUMAN	Serglycin	16870619	Serglycin constitutively secreted by myeloma plasma cells is a potent inhibitor of bone mineralization in vitro.

Q8MV48	GALT7_DROME	N-acetylgalactosaminyltransferase 7	11925450	Functional conservation of subfamilies of putative UDP-N- acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferases in Drosophila, Caenorhabditis elegans, and mammals. One subfamily composed of l(2)35Aa is essential in Drosophila.

Q8CHN8	MASP1_RAT	Mannan-binding lectin serine protease 1	10913141	Interaction of mannose-binding protein with associated serine proteases: effects of naturally occuring mutations.

P62268	RS23_RAT	40S ribosomal protein S23	8037726	The primary structure of rat ribosomal protein S23.

Q8N1B3	FA58A_HUMAN	Cyclin-related protein FAM58A	18297069	Mutations in the cyclin family member FAM58A cause an X-linked dominant disorder characterized by syndactyly, telecanthus and anogenital and renal malformations.

P43605	ECO1_YEAST	N-acetyltransferase ECO1	15355977	The spindle pole body assembly component Mps3p/Nep98p functions in sister chromatid cohesion.

Q9ZWS9	ARR3_ARATH	Two-component response regulator ARR3	14973166	Type-A Arabidopsis response regulators are partially redundant negative regulators of cytokinin signaling.

Q42371	ERECT_ARATH	LRR receptor-like serine/threonine-protein kinase ERECTA	16126863	Interaction of auxin and ERECTA in elaborating Arabidopsis inflorescence architecture revealed by the activation tagging of a new member of the YUCCA family putative flavin monooxygenases.

Q9NZU1	FLRT1_HUMAN	Leucine-rich repeat transmembrane protein FLRT1	10644439	Identification of FLRT1, FLRT2, and FLRT3: a novel family of transmembrane leucine-rich repeat proteins.

Q14832	GRM3_HUMAN	Metabotropic glutamate receptor 3	8840013	Molecular characterization and localization of human metabotropic glutamate receptor type 3.

P22731	LIVF_ECOLI	High-affinity branched-chain amino acid transport ATP-binding protein livF	2195019	Nucleotide sequence and genetic characterization reveal six essential genes for the LIV-I and LS transport systems of Escherichia coli.

P21592	COX10_YEAST	Protoheme IX farnesyltransferase, mitochondrial	8118433	On the functions of the yeast COX10 and COX11 gene products.

Q61419	CMAH_MOUSE	Cytidine monophosphate-N-acetylneuraminic acid hydroxylase	7608218	Molecular cloning of cytidine monophospho-N-acetylneuraminic acid hydroxylase.

P46736	BRCC3_HUMAN	Lys-63-specific deubiquitinase BRCC36	19214193	K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC- associated Brcc36 and proteasomal Poh1.

Q09174	GMA12_SCHPO	Alpha-1,2-galactosyltransferase	9839953	Differences in in vivo acceptor specificity of two galactosyltransferases, the gmh3+ and gma12+ gene products from Schizosaccharomyces pombe.

Q9Y6B7	AP4B1_HUMAN	AP-4 complex subunit beta-1	10066790	AP-4, a novel protein complex related to clathrin adaptors.

O75072	FKTN_HUMAN	Fukutin	9690476	An ancient retrotransposal insertion causes Fukuyama-type congenital muscular dystrophy.

Q8H186	Y3545_ARATH	Probable receptor-like protein kinase At3g55450	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q9FLP0	MA651_ARATH	65-kDa microtubule-associated protein 1	19060108	The C-terminal variable region specifies the dynamic properties of Arabidopsis microtubule-associated protein MAP65 isotypes.

Q12234	RUD3_YEAST	GRIP domain-containing protein RUD3	15504911	The GTPase Arf1p and the ER to Golgi cargo receptor Erv14p cooperate to recruit the golgin Rud3p to the cis-Golgi.

O60129	FKH2_SCHPO	Fork head protein homolog 2	15777722	Characterisation of two novel fork-head gene homologues of Schizosaccharomyces pombe: their involvement in cell cycle and sexual differentiation.

P86170	MEP_MELAF	Melectin	18942691	Melectin: a novel antimicrobial peptide from the venom of the cleptoparasitic bee Melecta albifrons.

Q19317	NBEA_CAEEL	Putative neurobeachin homolog	17215302	SEL-2, the C. elegans neurobeachin/LRBA homolog, is a negative regulator of lin-12/Notch activity and affects endosomal traffic in polarized epithelial cells.

P30988	CALCR_HUMAN	Calcitonin receptor	8078488	Cloning and characterization of an abundant subtype of the human calcitonin receptor.

Q05733	DCHS_DROME	Histidine decarboxylase	8096176	Genetic and molecular identification of a Drosophila histidine decarboxylase gene required in photoreceptor transmitter synthesis.

P16228	CATE_RAT	Cathepsin E	9572291	Identification of cellular compartments involved in processing of cathepsin E in primary cultures of rat microglia.

Q8WXC3	PYDC1_HUMAN	Pyrin domain-containing protein 1	12656673	The PAAD/PYRIN-only protein POP1/ASC2 is a modulator of ASC-mediated nuclear-factor-kappa B and pro-caspase-1 regulation.

Q9ERK9	P2RY6_MOUSE	P2Y purinoceptor 6	11259526	Cloning and functional characterization of two murine uridine nucleotide receptors reveal a potential target for correcting ion transport deficiency in cystic fibrosis gallbladder.

P32561	RPD3_YEAST	Histone deacetylase RPD3	16286008	Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex.

Q6DID7	WLS_MOUSE	Protein wntless homolog	19841259	Reciprocal regulation of Wnt and Gpr177/mouse Wntless is required for embryonic axis formation.

P24941	CDK2_HUMAN	Cell division protein kinase 2	1396589	Cell cycle regulation of CDK2 activity by phosphorylation of Thr160 and Tyr15.

Q9GYU7	MED10_DROME	Mediator of RNA polymerase II transcription subunit 10	16751183	Coactivator cross-talk specifies transcriptional output.

Q84UU4	HUMS_ARATH	Alpha-humulene/(-)-(E)-beta-caryophyllene synthase	12566586	Biosynthesis and emission of terpenoid volatiles from Arabidopsis flowers.

Q9CZP0	UFSP1_MOUSE	Ufm1-specific protease 1	18321862	Structural basis for Ufm1 processing by UfSP1.

O55112	AFF2_MOUSE	AF4/FMR2 family member 2	19136466	FRAXE-associated mental retardation protein (FMR2) is an RNA-binding protein with high affinity for G-quartet RNA forming structure.

Q9LJX0	AB19B_ARATH	ABC transporter B family member 19	15908594	Two homologous ATP-binding cassette transporter proteins, AtMDR1 and AtPGP1, regulate Arabidopsis photomorphogenesis and root development by mediating polar auxin transport.

P53866	SQS1_YEAST	Protein SQS1	16945917	Inhibition of a spliceosome turnover pathway suppresses splicing defects.

O15304	SIVA_HUMAN	Apoptosis regulatory protein Siva	16491128	Siva-1 negatively regulates NF-kappaB activity: effect on T-cell receptor-mediated activation-induced cell death (AICD).

P13773	CAR1_DICDI	Cyclic AMP receptor 1	1849108	Gene targeting of the aggregation stage cAMP receptor cAR1 in Dictyostelium.

Q06402	1A12_ARATH	1-aminocyclopropane-1-carboxylate synthase 2	8566772	Characterization of two members (ACS1 and ACS3) of the 1- aminocyclopropane-1-carboxylate synthase gene family of Arabidopsis thaliana.

O74400	YOCE_SCHPO	Uncharacterized RNA-binding protein C4F6.14	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O59941	VATD_NEUCR	V-type proton ATPase subunit D	10340846	The structure of the vacuolar ATPase in Neurospora crassa.

Q9W4S7	MYC_DROME	Myc protein	15182669	The Drosophila F box protein archipelago regulates dMyc protein levels in vivo.

P25847	MSH2_YEAST	DNA mismatch repair protein MSH2	9545323	ATP-dependent assembly of a ternary complex consisting of a DNA mismatch and the yeast MSH2-MSH6 and MLH1-PMS1 protein complexes.

Q8WQA4	EXC4_CAEEL	Chloride intracellular channel exc-4	14684823	A C. elegans CLIC-like protein required for intracellular tube formation and maintenance.

Q06623	HDA3_YEAST	HDA1 complex subunit 3	8663039	HDA1 and HDA3 are components of a yeast histone deacetylase (HDA) complex.

P53394	SULX_YEAST	Putative sulfate transporter YPR003C	14562095	Global analysis of protein localization in budding yeast.

P78352	DLG4_HUMAN	Disks large homolog 4	19118189	Preso, a novel PSD-95-interacting FERM and PDZ domain protein that regulates dendritic spine morphogenesis.

O13286	SRW1_SCHPO	WD repeat-containing protein srw1	10921878	Fission yeast Fizzy-related protein srw1p is a G(1)-specific promoter of mitotic cyclin B degradation.

Q9Y7Y6	YOY4_SCHPO	Uncharacterized protein C342.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P70610	DOC2B_RAT	Double C2-like domain-containing protein beta	20150444	Doc2b is a high-affinity Ca2+ sensor for spontaneous neurotransmitter release.

O94396	PUS1_SCHPO	tRNA pseudouridine synthase 1	11095668	Cloning and characterization of the Schizosaccharomyces pombe tRNA: pseudouridine synthase Pus1p.

O75459	GAGB1_HUMAN	G antigen family B member 1	9651357	Isolation and characterization of PAGE-1 and GAGE-7: new genes expressed in the LNCaP prostate cancer progression model that share homology with melanoma-associated antigens.

Q9W2B2	GR48C_DROME	Putative gustatory receptor 58c	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

O74432	GET4_SCHPO	Golgi to ER traffic protein 4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q5HZJ0	RNC_MOUSE	Ribonuclease 3	19632182	Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation.

Q6LA53	AAR2_SCHPO	A1 cistron-splicing factor aar2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P32597	STH1_YEAST	Nuclear protein STH1/NPS1	12183366	Chromatin remodeling by RSC involves ATP-dependent DNA translocation.

Q9Y608	LRRF2_HUMAN	Leucine-rich repeat flightless-interacting protein 2	15677333	Identification of the Wnt signaling activator leucine-rich repeat in Flightless interaction protein 2 by a genome-wide functional analysis.

Q8WYB5	MYST4_HUMAN	Histone acetyltransferase MYST4	16387653	ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.

O43024	YGVA_SCHPO	CUE domain-containing protein C354.10	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O65041	UBA3_ARATH	NEDD8-activating enzyme E1 catalytic subunit	10611386	The Arabidopsis cullin AtCUL1 is modified by the ubiquitin-related protein RUB1.

P86410	RLGPB_RAT	Ral GTPase-activating protein subunit beta	19520869	Tuberous sclerosis tumor suppressor complex-like complexes act as GTPase-activating proteins for Ral GTPases.

P22774	HSP7M_SCHPO	Heat shock 70 kDa protein, mitochondrial	2123810	Isolation of a gene encoding a mitochondrial HSP70 protein from Schizosaccharomyces pombe.

O22467	MSI1_ARATH	WD-40 repeat-containing protein MSI1	12736201	Arabidopsis MSI1 is required for epigenetic maintenance of reproductive development.

O75386	TULP3_HUMAN	Tubby-related protein 3	11375483	G-protein signaling through tubby proteins.

Q9H213	MAGH1_HUMAN	Melanoma-associated antigen H1	10948432	Improved PCR-based subtractive hybridization strategy for cloning differentially expressed genes.

Q10412	RSC58_SCHPO	Chromatin structure-remodeling complex subunit rsc58	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q05519	SRS11_HUMAN	Serine/arginine-rich splicing factor 11	1896467	Primary structure of a human arginine-rich nuclear protein that colocalizes with spliceosome components.

Q9M066	C90C1_ARATH	3-epi-6-deoxocathasterone 23-monooxygenase	17138693	C-23 hydroxylation by Arabidopsis CYP90C1 and CYP90D1 reveals a novel shortcut in brassinosteroid biosynthesis.

Q13263	TIF1B_HUMAN	Transcription intermediary factor 1-beta	8769649	KAP-1, a novel corepressor for the highly conserved KRAB repression domain.

O94282	CTU1_SCHPO	Cytoplasmic tRNA 2-thiolation protein 1	18391219	The conserved wobble uridine tRNA thiolase Ctu1-Ctu2 is required to maintain genome integrity.

P47989	XDH_HUMAN	Xanthine dehydrogenase/oxidase	17301077	Human xanthine oxidase changes its substrate specificity to aldehyde oxidase type upon mutation of amino acid residues in the active site: roles of active site residues in binding and activation of purine substrate.

Q92207	HOG1_CANAL	Mitogen-activated protein kinase HOG1	16151209	The MAP kinase Hog1p differentially regulates stress-induced production and accumulation of glycerol and D-arabitol in Candida albicans.

Q62735	NR1H4_RAT	Bile acid receptor	12718893	Structural basis for bile acid binding and activation of the nuclear receptor FXR.

Q9SAB4	PPR33_ARATH	Pentatricopeptide repeat-containing protein At1g11630, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q9V460	SPT5H_DROME	Transcription elongation factor SPT5	15380072	Locus-specific requirements for Spt5 in transcriptional activation and repression in Drosophila.

P15121	ALDR_HUMAN	Aldose reductase	8435445	Aldose reductase is involved in long-term adaptation of EUE cells to hyperosmotic stress.

P53804	TTC3_HUMAN	E3 ubiquitin-protein ligase TTC3	20059950	The E3 ligase TTC3 facilitates ubiquitination and degradation of phosphorylated Akt.

Q9UKX5	ITA11_HUMAN	Integrin alpha-11	10464311	cDNA cloning and chromosomal localization of human alpha(11) integrin. A collagen-binding, I domain-containing, beta(1)-associated integrin alpha-chain present in muscle tissues.

O14964	HGS_HUMAN	Hepatocyte growth factor-regulated tyrosine kinase substrate	10861283	The neurofibromatosis 2 tumor suppressor protein interacts with hepatocyte growth factor-regulated tyrosine kinase substrate.

P55899	FCGRN_HUMAN	IgG receptor FcRn large subunit p51	7964511	A major histocompatibility complex class I-like Fc receptor cloned from human placenta: possible role in transfer of immunoglobulin G from mother to fetus.

P0AD01	DCUR_ECOLI	Transcriptional regulatory protein dcuR	12167640	Function of DcuS from Escherichia coli as a fumarate-stimulated histidine protein kinase in vitro.

Q9Y4P1	ATG4B_HUMAN	Cysteine protease ATG4B	15169837	LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation.

Q9P0W0	IFNK_HUMAN	Interferon kappa	11514542	Interferon-kappa, a novel type I interferon expressed in human keratinocytes.

P63241	IF5A1_HUMAN	Eukaryotic translation initiation factor 5A-1	10944119	Exportin 4: a mediator of a novel nuclear export pathway in higher eukaryotes.

P15367	SEC11_YEAST	Signal peptidase complex catalytic subunit SEC11	10206957	The catalytic mechanism of endoplasmic reticulum signal peptidase appears to be distinct from most eubacterial signal peptidases.

Q9Y4K3	TRAF6_HUMAN	TNF receptor-associated factor 6	19713527	The E3 ligase TRAF6 regulates Akt ubiquitination and activation.

Q98SR9	TWS1B_DANRE	Twisted gastrulation protein homolog 1-B	15525664	Twisted gastrulation promotes BMP signaling in zebrafish dorsal- ventral axial patterning.

Q04412	AGE1_YEAST	ADP-ribosylation factor GTPase-activating protein effector protein 1	12627398	Four ARF GAPs in Saccharomyces cerevisiae have both overlapping and distinct functions.

P27111	CYNR_ECOLI	HTH-type transcriptional regulator cynR	8253686	Expression and purification of the cynR regulatory gene product: CynR is a DNA-binding protein.

P47709	RP3A_RAT	Rabphilin-3A	10025402	Structural basis of Rab effector specificity: crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A.

P38985	SRP14_YEAST	Signal recognition particle subunit SRP14	7925282	Subunits of the Saccharomyces cerevisiae signal recognition particle required for its functional expression.

P34709	TRA2_CAEEL	Sex-determining transformer protein 2	10364161	Negative regulation of male development in Caenorhabditis elegans by a protein-protein interaction between TRA-2A and FEM-3.

Q68CZ1	FTM_HUMAN	Protein fantom	19464661	Thromboxane A2-induced signal transduction is negatively regulated by KIAA1005 that directly interacts with thromboxane A2 receptor.

P42753	CCD31_ARATH	Cyclin-D3-1	10848578	Sugar control of the plant cell cycle: differential regulation of Arabidopsis D-type cyclin gene expression.

P43320	CRBB2_HUMAN	Beta-crystallin B2	9158139	Autosomal dominant cerulean cataract is associated with a chain termination mutation in the human beta-crystallin gene CRYBB2.

P53163	MNP1_YEAST	54S ribosomal protein L12, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

P39714	BDH1_YEAST	Diacetyl reductase [(R)-acetoin forming]	10938079	Characterization of a (2R,3R)-2,3-butanediol dehydrogenase as the Saccharomyces cerevisiae YAL060W gene product. Disruption and induction of the gene.

Q9UBP8	KAAG1_HUMAN	Kidney-associated antigen 1	10601354	A new antigen recognized by cytolytic T lymphocytes on a human kidney tumor results from reverse strand transcription.

Q9Y691	KCMB2_HUMAN	Calcium-activated potassium channel subunit beta-2	10097176	Molecular basis of fast inactivation in voltage and Ca2+-activated K+ channels: a transmembrane beta-subunit homolog.

Q9C7U5	E132_ARATH	Glucan endo-1,3-beta-glucosidase 2	12805588	Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis.

P32561	RPD3_YEAST	Histone deacetylase RPD3	10899127	Cyclophilin A and Ess1 interact with and regulate silencing by the Sin3-Rpd3 histone deacetylase.

O13547	CCW14_YEAST	Covalently-linked cell wall protein 14	9079899	Identification of a mannoprotein present in the inner layer of the cell wall of Saccharomyces cerevisiae.

P45395	KDSD_ECOLI	Arabinose 5-phosphate isomerase	12805358	Escherichia coli YrbH is a D-arabinose 5-phosphate isomerase.

Q9BSU3	NAA11_HUMAN	N-alpha-acetyltransferase 11, NatA catalytic subunit	16638120	Characterization of hARD2, a processed hARD1 gene duplicate, encoding a human protein N-alpha-acetyltransferase.

P43593	UBP6_YEAST	Ubiquitin carboxyl-terminal hydrolase 6	14581483	Complementary roles for Rpn11 and Ubp6 in deubiquitination and proteolysis by the proteasome.

P33599	NUOCD_ECOLI	NADH-quinone oxidoreductase subunit C/D	7607227	Isolation and characterization of the proton-translocating NADH: ubiquinone oxidoreductase from Escherichia coli.

Q13936	CAC1C_HUMAN	Voltage-dependent L-type calcium channel subunit alpha-1C	8392192	Cloning, chromosomal localization, and functional expression of the alpha-1 subunit of the L-type voltage-dependent calcium channel from normal human heart.

Q9P791	YN8C_SCHPO	Uncharacterized Nudix hydrolase P35G2.12	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P77304	DTPA_ECOLI	Dipeptide and tripeptide permease A	18485005	DtpB (YhiP) and DtpA (TppB, YdgR) are prototypical proton-dependent peptide transporters of Escherichia coli.

Q10943	ARF12_CAEEL	ADP-ribosylation factor 1-like 2	15576487	Functional genomic analysis of the ADP-ribosylation factor family of GTPases: phylogeny among diverse eukaryotes and function in C. elegans.

Q9BY78	RNF26_HUMAN	RING finger protein 26	11352657	Molecular cloning and characterization of RNF26 on human chromosome 11q23 region, encoding a novel RING finger protein with leucine zipper.

P06310	KV206_HUMAN	Ig kappa chain V-II region RPMI 6410	2997711	Human immunoglobulin kappa light chain genes of subgroups II and III.

P09874	PARP1_HUMAN	Poly [ADP-ribose] polymerase 1	15044383	Aprataxin, a novel protein that protects against genotoxic stress.

P34709	TRA2_CAEEL	Sex-determining transformer protein 2	12477393	Rapid coevolution of the nematode sex-determining genes fem-3 and tra-2.

Q04121	NHX1_YEAST	Endosomal/prevacuolar sodium/hydrogen exchanger	9334180	Intracellular sequestration of sodium by a novel Na+/H+ exchanger in yeast is enhanced by mutations in the plasma membrane H+-ATPase. Insights into mechanisms of sodium tolerance.

Q8CGU1	CACO1_MOUSE	Calcium-binding and coiled-coil domain-containing protein 1	16344550	Differential use of functional domains by coiled-coil coactivator in its synergistic coactivator function with beta-catenin or GRIP1.

Q03412	UNC7_CAEEL	Innexin unc-7	7681023	Molecular and genetic analysis of unc-7, a Caenorhabditis elegans gene required for coordinated locomotion.

Q8RYC8	ARFS_ARATH	Auxin response factor 19	16461383	A role for auxin response factor 19 in auxin and ethylene signaling in Arabidopsis.

A5HAK0	RNSL3_DANRE	Ribonuclease-like 3	18508078	Ribonuclease A homologues of the zebrafish: polymorphism, crystal structures of two representatives and their evolutionary implications.

Q9Y2T4	2ABG_HUMAN	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform	10945473	Molecular cloning and mapping of the brain-abundant B1gamma subunit of protein phosphatase 2A, PPP2R2C, to human chromosome 4p16.

O60784	TOM1_HUMAN	Target of Myb protein 1	14613930	Endofin recruits TOM1 to endosomes.

P87235	RHP42_SCHPO	DNA repair protein rhp42	12807767	Repair of damaged and mismatched DNA by the XPC homologues Rhp41 and Rhp42 of fission yeast.

P08758	ANXA5_HUMAN	Annexin A5	2967291	Cloning and expression of cDNA for human endonexin II, a Ca2+ and phospholipid binding protein.

Q62746	SYT6_RAT	Synaptotagmin-6	7791877	Ca(2+)-dependent and -independent activities of neural and non-neural synaptotagmins.

Q58576	PAN_METJA	Proteasome-activating nucleotidase	10473546	An archaebacterial ATPase, homologous to ATPases in the eukaryotic 26 S proteasome, activates protein breakdown by 20 S proteasomes.

Q9NP94	S39A2_HUMAN	Zinc transporter ZIP2	10681536	Functional expression of the human hZIP2 zinc transporter.

P10275	ANDR_HUMAN	Androgen receptor	3353726	Molecular cloning of human and rat complementary DNA encoding androgen receptors.

Q15154	PCM1_HUMAN	Pericentriolar material 1 protein	15107855	The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression.

P40337	VHL_HUMAN	Von Hippel-Lindau disease tumor suppressor	12169691	The von Hippel-Lindau tumor suppressor stabilizes novel plant homeodomain protein Jade-1.

Q99717	SMAD5_HUMAN	Mothers against decapentaplegic homolog 5	10708949	TGF-beta signaling by Smad proteins.

Q6NN85	SSH_DROME	Protein phosphatase Slingshot	16169194	Slingshot cofilin phosphatase localization is regulated by receptor tyrosine kinases and regulates cytoskeletal structure in the developing Drosophila eye.

P23321	PSBO1_ARATH	Oxygen-evolving enhancer protein 1-1, chloroplastic	11826309	Central functions of the lumenal and peripheral thylakoid proteome of Arabidopsis determined by experimentation and genome-wide prediction.

Q99N34	DFFB_RAT	DNA fragmentation factor subunit beta	11425895	Caspase-activated DNase/DNA fragmentation factor 40 mediates apoptotic DNA fragmentation in transient cerebral ischemia and in neuronal cultures.

P53051	MALX3_YEAST	Oligo-1,6-glucosidase	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

O49203	NDK3_ARATH	Nucleoside diphosphate kinase III, chloroplastic/mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q06889	EGR3_HUMAN	Early growth response protein 3	1906159	EGR3, a novel member of the Egr family of genes encoding immediate- early transcription factors.

P38620	KPR2_YEAST	Ribose-phosphate pyrophosphokinase 2	10212224	Genetic analysis and enzyme activity suggest the existence of more than one minimal functional unit capable of synthesizing phosphoribosyl pyrophosphate in Saccharomyces cerevisiae.

P97822	AN32E_MOUSE	Acidic leucine-rich nuclear phosphoprotein 32 family member E	11430900	Differential expression of CPD1 during postnatal development in the mouse cerebellum.

Q91V10	VSX1_MOUSE	Visual system homeobox 1	11731243	Vsx1, a rapidly evolving paired-like homeobox gene expressed in cone bipolar cells.

Q62645	NMDE4_RAT	Glutamate [NMDA] receptor subunit epsilon-4	7512349	Developmental and regional expression in the rat brain and functional properties of four NMDA receptors.

P47811	MK14_MOUSE	Mitogen-activated protein kinase 14	10601328	A novel regulatory mechanism of MAP kinases activation and nuclear translocation mediated by PKA and the PTP-SL tyrosine phosphatase.

P40646	SOX7_MOUSE	Transcription factor SOX-7	10320775	Isolation and characterization of a mouse SRY-related cDNA, mSox7.

P21953	ODBB_HUMAN	2-oxoisovalerate dehydrogenase subunit beta, mitochondrial	2365818	Maple syrup urine disease. Complete primary structure of the E1 beta subunit of human branched chain alpha-ketoacid dehydrogenase complex deduced from the nucleotide sequence and a gene analysis of patients with this disease.

P40522	VHR1_YEAST	Transcription factor VHR1	16533810	Vhr1p, a new transcription factor from budding yeast, regulates biotin-dependent expression of VHT1 and BIO5.

Q12797	ASPH_HUMAN	Aspartyl/asparaginyl beta-hydroxylase	10974562	cDNA cloning and characterization of human cardiac junctin.

Q9M439	BCAT2_ARATH	Branched-chain-amino-acid aminotransferase 2, chloroplastic	12068099	The branched-chain amino acid transaminase gene family in Arabidopsis encodes plastid and mitochondrial proteins.

Q13608	PEX6_HUMAN	Peroxisome assembly factor 2	8670792	The peroxisome biogenesis disorder group 4 gene, PXAAA1, encodes a cytoplasmic ATPase required for stability of the PTS1 receptor.

P36093	PHD1_YEAST	Putative transcription factor PHD1	8114741	Induction of pseudohyphal growth by overexpression of PHD1, a Saccharomyces cerevisiae gene related to transcriptional regulators of fungal development.

P40084	RTR1_YEAST	RNA polymerase II subunit B1 CTD phosphatase RTR1	19394294	Rtr1 is a CTD phosphatase that regulates RNA polymerase II during the transition from serine 5 to serine 2 phosphorylation.

O65020	ETO1_ARATH	Ethylene-overproduction protein 1	15118728	Regulation of ethylene gas biosynthesis by the Arabidopsis ETO1 protein.

P49796	RGS3_HUMAN	Regulator of G-protein signaling 3	8602223	Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family.

Q9ULY5	CLC4E_HUMAN	C-type lectin domain family 4 member E	10528209	A novel LPS-inducible C-type lectin is a transcriptional target of NF-IL6 in macrophages.

Q02046	MTD1_YEAST	Methylenetetrahydrofolate dehydrogenase [NAD+]	8416923	Cloning and characterization of the Saccharomyces cerevisiae gene encoding NAD-dependent 5,10-methylenetetrahydrofolate dehydrogenase.

Q93ZA0	NYC1_ARATH	Probable chlorophyll(ide) b reductase NYC1, chloroplastic	19403948	Participation of chlorophyll b reductase in the initial step of the degradation of light-harvesting chlorophyll a/b-protein complexes in Arabidopsis.

P18910	ANPRA_RAT	Atrial natriuretic peptide receptor 1	1679239	Site-directed mutational analysis of a membrane guanylate cyclase cDNA reveals the atrial natriuretic factor signaling site.

P09064	IF2B_YEAST	Eukaryotic translation initiation factor 2 subunit beta	3136928	Mutations at a Zn(II) finger motif in the yeast eIF-2 beta gene alter ribosomal start-site selection during the scanning process.

P63345	ARC_MYCTU	Proteasome-associated ATPase	14671303	The proteasome of Mycobacterium tuberculosis is required for resistance to nitric oxide.

P69566	RANB9_MOUSE	Ran-binding protein 9	14648869	Mouse RanBPM is a partner gene to a germline specific RNA helicase, mouse vasa homolog protein.

Q9H4L7	SMRCD_HUMAN	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1	11031099	SMARCAD1, a novel human helicase family-defining member associated with genetic instability: cloning, expression, and mapping to 4q22- q23, a band rich in breakpoints and deletion mutants involved in several human diseases.

O59709	GIT7_SCHPO	Glucose-insensitive transcription protein 7	12456004	Schizosaccharomyces pombe Git7p, a member of the Saccharomyces cerevisiae Sgtlp family, is required for glucose and cyclic AMP signaling, cell wall integrity, and septation.

P14060	3BHS1_HUMAN	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1	2243100	Characterization of human 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase gene and its expression in mammalian cells.

Q61286	HTF4_MOUSE	Transcription factor 12	1321336	Murine helix-loop-helix transcriptional activator proteins binding to the E-box motif of the Akv murine leukemia virus enhancer identified by cDNA cloning.

Q12329	HSP42_YEAST	Heat shock protein 42	8576246	Multimerization of Hsp42p, a novel heat shock protein of Saccharomyces cerevisiae, is dependent on a conserved carboxyl- terminal sequence.

O13837	GATA_SCHPO	4-aminobutyrate aminotransferase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q05779	COQ9_YEAST	Ubiquinone biosynthesis protein COQ9, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q8JZX4	SPF45_MOUSE	Splicing factor 45	9731529	Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex.

O76061	STC2_HUMAN	Stanniocalcin-2	9753616	Molecular cloning of a second human stanniocalcin homologue (STC2).

Q9JHK4	PGTA_MOUSE	Geranylgeranyl transferase type-2 subunit alpha	10737774	Rab geranylgeranyl transferase alpha mutation in the gunmetal mouse reduces Rab prenylation and platelet synthesis.

P13574	STE12_YEAST	Protein STE12	8339934	Coupling of cell identity to signal response in yeast: interaction between the alpha-1 and STE12 proteins.

O95977	S1PR4_HUMAN	Sphingosine 1-phosphate receptor 4	10679247	Edg-6 as a putative sphingosine 1-phosphate receptor coupling to Ca(2+) signaling pathway.

Q8K1I7	WIPF1_MOUSE	WAS/WASL-interacting protein family member 1	12147689	Phosphatidylinositol 4,5-biphosphate (PIP2)-induced vesicle movement depends on N-WASP and involves Nck, WIP, and Grb2.

Q9MA55	ACBP4_ARATH	Acyl-CoA-binding domain-containing protein 4	18773301	Arabidopsis acyl-CoA-binding proteins ACBP4 and ACBP5 are subcellularly localized to the cytosol and ACBP4 depletion affects membrane lipid composition.

Q9H081	MIS12_HUMAN	Protein MIS12 homolog	16585270	The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation.

O14002	MAK2_SCHPO	Peroxide stress-activated histidine kinase mak2	11179424	Peroxide sensors for the fission yeast stress-activated mitogen- activated protein kinase pathway.

Q54HY0	PDE7_DICDI	cAMP/cGMP-dependent 3',5'-cAMP/cGMP phosphodiesterase 7	17040207	Seven Dictyostelium discoideum phosphodiesterases degrade three pools of cAMP and cGMP.

Q9HBE5	IL21R_HUMAN	Interleukin-21 receptor	11081504	Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function.

Q92692	PVRL2_HUMAN	Poliovirus receptor-related protein 2	9657005	A cell surface protein with herpesvirus entry activity (HveB) confers susceptibility to infection by mutants of herpes simplex virus type 1, herpes simplex virus type 2, and pseudorabies virus.

O74430	TGCE1_SCHPO	Probable lipase C1672.09	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q4JL84	MYB59_ARATH	Transcription factor MYB59	16463103	The MYB transcription factor superfamily of Arabidopsis: expression analysis and phylogenetic comparison with the rice MYB family.

Q18217	ULA1_CAEEL	NEDD8-activating enzyme E1 regulatory subunit	10993680	The NED-8 conjugating system in Caenorhabditis elegans is required for embryogenesis and terminal differentiation of the hypodermis.

Q9WV60	GSK3B_MOUSE	Glycogen synthase kinase-3 beta	19303846	Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling.

O14672	ADA10_HUMAN	Disintegrin and metalloproteinase domain-containing protein 10	12475894	ADAM10-mediated cleavage of L1 adhesion molecule at the cell surface and in released membrane vesicles.

P05783	K1C18_HUMAN	Keratin, type I cytoskeletal 18	15731013	Identification of trichoplein, a novel keratin filament-binding protein.

Q9NZN9	AIPL1_HUMAN	Aryl-hydrocarbon-interacting protein-like 1	10615133	Mutations in a novel photoreceptor-pineal gene on 17p cause Leber congenital amaurosis.

O49255	NAC29_ARATH	NAC domain-containing protein 29	9489703	A homolog of NO APICAL MERISTEM is an immediate target of the floral homeotic genes APETALA3/PISTILLATA.

O13828	DCP2_SCHPO	mRNA decapping complex subunit 2	18280239	Structural basis of dcp2 recognition and activation by dcp1.

Q39055	CNX2_ARATH	Molybdopterin biosynthesis protein CNX2	7890743	Isolation of two Arabidopsis cDNAs involved in early steps of molybdenum cofactor biosynthesis by functional complementation of Escherichia coli mutants.

Q08230	SDHF2_YEAST	Succinate dehydrogenase assembly factor 2, mitochondrial	12586695	Large-scale functional genomic analysis of sporulation and meiosis in Saccharomyces cerevisiae.

O60476	MA1A2_HUMAN	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB	9592125	Molecular cloning, chromosomal mapping and tissue-specific expression of a novel human alpha-1,2-mannosidase gene involved in N-glycan maturation.

Q6Q4H1	JMJD6_HYDVU	Bifunctional arginine demethylase and lysyl-hydroxylase PSR	15193161	The phosphatidylserine receptor from Hydra is a nuclear protein with potential Fe(II) dependent oxygenase activity.

P0A9G4	CUER_ECOLI	HTH-type transcriptional regulator cueR	11136469	CueR (YbbI) of Escherichia coli is a MerR family regulator controlling expression of the copper exporter CopA.

P24867	PCL1_YEAST	PHO85 cyclin-1	14688790	Late-G1 cyclin-CDK activity is essential for control of cell morphogenesis in budding yeast.

Q9H2G4	TSYL2_HUMAN	Testis-specific Y-encoded-like protein 2	11395479	SET-related cell division autoantigen-1 (CDA1) arrests cell growth.

Q9SYG9	CCX4_ARATH	Cation/calcium exchanger 4	18775974	AtCCX3 is an Arabidopsis endomembrane H+ -dependent K+ transporter.

Q62733	LAP2_RAT	Lamina-associated polypeptide 2, isoform beta	7737115	Cloning of a cDNA for lamina-associated polypeptide 2 (LAP2) and identification of regions that specify targeting to the nuclear envelope.

Q9SSA5	CYP38_ARATH	Peptidyl-prolyl cis-trans isomerase CYP38, chloroplastic	11826309	Central functions of the lumenal and peripheral thylakoid proteome of Arabidopsis determined by experimentation and genome-wide prediction.

P38297	FZO1_YEAST	Transmembrane GTPase FZO1	12808034	Mgm1p, a dynamin-related GTPase, is essential for fusion of the mitochondrial outer membrane.

P52824	DGKQ_HUMAN	Diacylglycerol kinase theta	12799190	Diacylglycerol kinase-theta is localized in the speckle domains of the nucleus.

Q9UBY9	HSPB7_HUMAN	Heat shock protein beta-7	10593960	Identification and characterization of cvHsp. A novel human small stress protein selectively expressed in cardiovascular and insulin- sensitive tissues.

P35194	UTP20_YEAST	U3 small nucleolar RNA-associated protein 20	15590835	The small-subunit processome is a ribosome assembly intermediate.

P79772	FOXD3_CHICK	Forkhead box protein D3	11684651	The winged-helix transcription factor Foxd3 suppresses interneuron differentiation and promotes neural crest cell fate.

P17745	EFTU_ARATH	Elongation factor Tu, chloroplastic	12766230	Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.

O42647	MUG94_SCHPO	Meiotically up-regulated gene 94 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P38881	NVJ1_YEAST	Nucleus-vacuole junction protein 1	16912077	Structure and function of nucleus-vacuole junctions: outer-nuclear- membrane targeting of Nvj1p and a role in tryptophan uptake.

Q9USS4	YOA2_SCHPO	Uncharacterized protein C557.02c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9SX93	PUP19_ARATH	Putative purine permease 19	10662864	A new family of high-affinity transporters for adenine, cytosine, and purine derivatives in Arabidopsis.

Q9V3I5	JIL1_DROME	Chromosomal serine/threonine-protein kinase JIL-1	10445035	JIL-1: a novel chromosomal tandem kinase implicated in transcriptional regulation in Drosophila.

P83686	NB5R3_PIG	NADH-cytochrome b5 reductase 3	7890048	Specific arrangement of three amino acid residues for flavin-binding barrel structures in NADH-cytochrome b5 reductase and the other flavin-dependent reductases.

P24001	IL32_HUMAN	Interleukin-32	1729377	Identification of a novel gene expressed in activated natural killer cells and T cells.

P17988	ST1A1_RAT	Sulfotransferase 1A1	1513323	Sequence analysis, in vitro translation and expression of the cDNA for rat liver minoxidil sulfotransferase.

P08648	ITA5_HUMAN	Integrin alpha-5	16051604	Cartilage oligomeric matrix protein/thrombospondin 5 supports chondrocyte attachment through interaction with integrins.

Q9Y5X5	NPFF2_HUMAN	Neuropeptide FF receptor 2	10079187	Sequence and tissue distribution of a novel G-protein-coupled receptor expressed prominently in human placenta.

P01286	SLIB_HUMAN	Somatoliberin	6192430	Cloning and sequence analysis of cDNA for the precursor of human growth hormone-releasing factor, somatocrinin.

P49281	NRAM2_HUMAN	Natural resistance-associated macrophage protein 2	12209011	Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: implications for regulation and cellular function.

P76346	MTFA_ECOLI	Protein mtfA	16855233	YeeI, a novel protein involved in modulation of the activity of the glucose-phosphotransferase system in Escherichia coli K-12.

Q5AU81	AFCA_EMENI	Alpha-fucosidase A	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

P49915	GUAA_HUMAN	GMP synthase [glutamine-hydrolyzing]	8089153	Human GMP synthetase. Protein purification, cloning, and functional expression of cDNA.

Q9ZU52	ALFC3_ARATH	Probable fructose-bisphosphate aldolase 3, chloroplastic	16461379	Protein profiling of plastoglobules in chloroplasts and chromoplasts. A surprising site for differential accumulation of metabolic enzymes.

Q14532	K1H2_HUMAN	Keratin, type I cuticular Ha2	7556444	Sequence data and chromosomal localization of human type I and type II hair keratin genes.

Q92764	KRT35_HUMAN	Keratin, type I cuticular Ha5	8823373	Genomic characterization of the human type I cuticular hair keratin hHa2 and identification of an adjacent novel type I hair keratin gene hHa5.

P30793	GCH1_HUMAN	GTP cyclohydrolase 1	2463916	Purification of GTP cyclohydrolase I from human liver and production of specific monoclonal antibodies.

Q2MHE4	HT1_ARATH	Serine/threonine-protein kinase HT1	16518390	Arabidopsis HT1 kinase controls stomatal movements in response to CO(2).

O95405	ZFYV9_HUMAN	Zinc finger FYVE domain-containing protein 9	9865696	SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor.

P62963	PROF1_RAT	Profilin-1	8651905	Enhanced glomerular profilin gene and protein expression in experimental mesangial proliferative glomerulonephritis.

O15265	ATX7_HUMAN	Ataxin-7	18206972	A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing.

P18054	LOX12_HUMAN	Arachidonate 12-lipoxygenase, 12S-type	2217179	Cloning of the cDNA for human 12-lipoxygenase.

P06703	S10A6_HUMAN	Protein S100-A6	12601007	Calcium- and cell cycle-dependent association of annexin 11 with the nuclear envelope.

P41437	IAP3_NPVOP	E3 ubiquitin-protein ligase IAP-3	15371430	VIAF, a conserved inhibitor of apoptosis (IAP)-interacting factor that modulates caspase activation.

P53680	AP2S1_HUMAN	AP-2 complex subunit sigma	9040778	Human CLAPS2 encoding AP17, a small chain of the clathrin-associated protein complex: cDNA cloning and chromosomal assignment to 19q13.2-->q13.3.

Q05084	ICA69_HUMAN	Islet cell autoantigen 1	12682071	Islet cell autoantigen of 69 kDa is an arfaptin-related protein associated with the Golgi complex of insulinoma INS-1 cells.

Q9R0P9	UCHL1_MOUSE	Ubiquitin carboxyl-terminal hydrolase isozyme L1	14695319	Role of ubiquitin carboxy terminal hydrolase-L1 in neural cell apoptosis induced by ischemic retinal injury in vivo.

P53628	SNF12_YEAST	Transcription regulatory protein SNF12	16204215	The RSC chromatin remodeling complex bears an essential fungal- specific protein module with broad functional roles.

Q9P7L8	SAP62_SCHPO	CWF complex protein sap62	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q39129	STR16_ARATH	Thiosulfate sulfurtransferase, chloroplastic	12482606	Identification and characterization of single-domain thiosulfate sulfurtransferases from Arabidopsis thaliana.

P36077	SRX1_YEAST	Sulfiredoxin	14586471	ATP-dependent reduction of cysteine-sulphinic acid by S. cerevisiae sulphiredoxin.

O35492	CLK3_MOUSE	Dual specificity protein kinase CLK3	9307018	Characterization and comparison of four serine- and arginine-rich (SR) protein kinases.

O43699	SIGL6_HUMAN	Sialic acid-binding Ig-like lectin 6	9465907	Molecular cloning of a novel gene similar to myeloid antigen CD33 and its specific expression in placenta.

Q9LVI8	GLN13_ARATH	Glutamine synthetase cytosolic isozyme 1-3	14757761	Kinetic properties and ammonium-dependent regulation of cytosolic isoenzymes of glutamine synthetase in Arabidopsis.

P70166	CPEB1_MOUSE	Cytoplasmic polyadenylation element-binding protein 1	16314516	Amyloid precursor proteins anchor CPEB to membranes and promote polyadenylation-induced translation.

Q9UUE5	NUP85_SCHPO	Nucleoporin nup85	15116432	Identification of genes encoding putative nucleoporins and transport factors in the fission yeast Schizosaccharomyces pombe: a deletion analysis.

P40515	FIS1_YEAST	Mitochondria fission 1 protein	11038183	Dnm1p GTPase-mediated mitochondrial fission is a multi-step process requiring the novel integral membrane component Fis1p.

P05187	PPB1_HUMAN	Alkaline phosphatase, placental type	3042787	Nucleotide sequence of the human placental alkaline phosphatase gene. Evolution of the 5' flanking region by deletion/substitution.

P55087	AQP4_HUMAN	Aquaporin-4	7559426	cDNA cloning, gene organization, and chromosomal localization of a human mercurial insensitive water channel. Evidence for distinct transcriptional units.

Q9Y535	RPC8_HUMAN	DNA-directed RNA polymerase III subunit RPC8	12391170	Characterization of human RNA polymerase III identifies orthologues for Saccharomyces cerevisiae RNA polymerase III subunits.

Q24434	ORD_DROME	Protein ORD	12429833	Meiotic cohesion requires accumulation of ORD on chromosomes before condensation.

Q9Y2G3	AT11B_HUMAN	Probable phospholipid-transporting ATPase IF	11015572	Differential expression of putative transbilayer amphipath transporters.

Q91V08	CLC2D_MOUSE	C-type lectin domain family 2 member D	11398965	Cloning of Clr, a new family of lectin-like genes localized between mouse Nkrp1a and Cd69.

P53155	YGI2_YEAST	Uncharacterized protein YGL082W	14562095	Global analysis of protein localization in budding yeast.

Q8MY12	MHCKC_DICDI	Myosin heavy chain kinase C	12475956	Novel myosin heavy chain kinase involved in disassembly of myosin II filaments and efficient cleavage in mitotic dictyostelium cells.

Q8W2F1	BH012_ARATH	Transcription factor MYC1	15361138	Comprehensive identification of Arabidopsis thaliana MYB transcription factors interacting with R/B-like BHLH proteins.

Q13105	ZBT17_HUMAN	Zinc finger and BTB domain-containing protein 17	9308237	Association of Myc with the zinc-finger protein Miz-1 defines a novel pathway for gene regulation by Myc.

P34707	SKN1_CAEEL	Protein skinhead-1	9628487	A new DNA-binding motif in the Skn-1 binding domain-DNA complex.

O60081	YQK7_SCHPO	Uncharacterized protein C1494.07	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P46500	SDZ15_CAEEL	Skn-1 dependent zygotic transcript 15 protein	15581881	Identification of lineage-specific zygotic transcripts in early Caenorhabditis elegans embryos.

O70481	UBR1_MOUSE	E3 ubiquitin-protein ligase UBR1	14585983	Female lethality and apoptosis of spermatocytes in mice lacking the UBR2 ubiquitin ligase of the N-end rule pathway.

Q5U259	ELV1B_XENLA	ELAV-like protein 1-B	19458392	Participation of Xenopus Elr-type proteins in vegetal mRNA localization during oogenesis.

Q15777	MPPD2_HUMAN	Metallophosphoesterase MPPED2	7527372	A WAGR region gene between PAX-6 and FSHB expressed in fetal brain.

Q03714	USA1_YEAST	U1 SNP1-associating protein 1	11425851	New roles for the Snp1 and Exo84 proteins in yeast pre-mRNA splicing.

P38247	SLM4_YEAST	Protein SLM4	15989961	The TOR and EGO protein complexes orchestrate microautophagy in yeast.

Q07325	CXCL9_HUMAN	C-X-C motif chemokine 9	8476424	HuMig: a new human member of the chemokine family of cytokines.

Q9Z250	LIN7A_RAT	Protein lin-7 homolog A	10362251	Isolation and characterization of mammalian homologues of Caenorhabditis elegans lin-7: localization at cell-cell junctions.

O74772	CWF14_SCHPO	Cell cycle control protein cwf14	11884590	Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

O13704	YEU5_SCHPO	Thioredoxin domain-containing protein C13F5.05, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9FV53	DEF1A_ARATH	Peptide deformylase 1A, chloroplastic	11733990	Distinctive features of the two classes of eukaryotic peptide deformylases.

P07215	MTCU_YEAST	Metallothionein	3902832	Yeast metallothionein. Sequence and metal-binding properties.

Q9CAD0	EGL1_ARATH	Transcription factor EGL1	15361138	Comprehensive identification of Arabidopsis thaliana MYB transcription factors interacting with R/B-like BHLH proteins.

P06737	PYGL_HUMAN	Glycogen phosphorylase, liver form	10980448	Human liver glycogen phosphorylase inhibitors bind at a new allosteric site.

P11710	FUS1_YEAST	Nuclear fusion protein FUS1	3313002	Identification and regulation of a gene required for cell fusion during mating of the yeast Saccharomyces cerevisiae.

Q9ESX2	SP6_MOUSE	Transcription factor Sp6	14551215	The Kruppel-like factor epiprofin is expressed by epithelium of developing teeth, hair follicles, and limb buds and promotes cell proliferation.

Q96RI1	NR1H4_HUMAN	Bile acid receptor	10334992	Identification of a nuclear receptor for bile acids.

O74964	RSC1_SCHPO	Chromatin structure-remodeling complex subunit rsc1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P32525	ECM25_YEAST	Protein ECM25	9335584	Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae.

Q9Y5K3	PCY1B_HUMAN	Choline-phosphate cytidylyltransferase B	9593753	Cloning and characterization of a second human CTP:phosphocholine cytidylyltransferase.

P60033	CD81_HUMAN	CD81 antigen	1695320	TAPA-1, the target of an antiproliferative antibody, defines a new family of transmembrane proteins.

P24004	PEX1_YEAST	Peroxisomal ATPase PEX1	16007078	Functional role of the AAA peroxins in dislocation of the cycling PTS1 receptor back to the cytosol.

Q96D31	CRCM1_HUMAN	Calcium release-activated calcium channel protein 1	16645049	CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry.

Q54NF8	SCAR_DICDI	Protein SCAR	16822579	Cell motility and SCAR localisation in axenically growing Dictyostelium cells.

Q960V3	MILT_DROME	Trafficking kinesin-binding protein milt	12495622	Axonal transport of mitochondria to synapses depends on milton, a novel Drosophila protein.

O95299	NDUAA_HUMAN	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

Q61152	PTN18_MOUSE	Tyrosine-protein phosphatase non-receptor type 18	8875997	Cloning and characterization of PTP-K1, a novel nonreceptor protein tyrosine phosphatase highly expressed in bone marrow.

Q16696	CP2AD_HUMAN	Cytochrome P450 2A13	17428784	Structure of the human lung cytochrome P450 2A13.

P36630	CG22_SCHPO	G2/mitotic-specific cyclin cig2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O00255	MEN1_HUMAN	Menin	17500065	PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.

Q7SZL5	MTUS1_XENLA	Microtubule-associated tumor suppressor 1 homolog	12919681	An inner centromere protein that stimulates the microtubule depolymerizing activity of a KinI kinesin.

Q99728	BARD1_HUMAN	BRCA1-associated RING domain protein 1	10026184	Mapping the functional domains of BRCA1. Interaction of the ring finger domains of BRCA1 and BARD1.

Q8T4F7	ENA_DROME	Protein enabled	7535279	Enabled, a dosage-sensitive suppressor of mutations in the Drosophila Abl tyrosine kinase, encodes an Abl substrate with SH3 domain-binding properties.

Q9R210	TFEB_MOUSE	Transcription factor EB	16936731	Transcription factors TFE3 and TFEB are critical for CD40 ligand expression and thymus-dependent humoral immunity.

Q9UBD9	CLCF1_HUMAN	Cardiotrophin-like cytokine factor 1	10448081	Computational EST database analysis identifies a novel member of the neuropoietic cytokine family.

Q03344	ATIF1_RAT	ATPase inhibitor, mitochondrial	8442667	Regulation of the mitochondrial ATP synthase/ATPase complex: cDNA cloning, sequence, overexpression, and secondary structural characterization of a functional protein inhibitor.

Q02156	KPCE_HUMAN	Protein kinase C epsilon type	1382605	Sequence and expression of human protein kinase C-epsilon.

Q99N50	SYTL2_MOUSE	Synaptotagmin-like protein 2	11243866	Synaptotagmin-like protein 1-3: a novel family of C-terminal-type tandem C2 proteins.

P14136	GFAP_HUMAN	Glial fibrillary acidic protein	2740350	Molecular cloning and primary structure of human glial fibrillary acidic protein.

Q96MT8	CEP63_HUMAN	Centrosomal protein of 63 kDa	14654843	Proteomic characterization of the human centrosome by protein correlation profiling.

Q9UTN3	CID14_SCHPO	Poly(A) RNA polymerase cid14	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q14974	IMB1_HUMAN	Importin subunit beta-1	7615630	Sequence and characterization of cytoplasmic nuclear protein import factor p97.

P21757	MSRE_HUMAN	Macrophage scavenger receptor types I and II	2251254	Human macrophage scavenger receptors: primary structure, expression, and localization in atherosclerotic lesions.

P45478	PPT1_BOVIN	Palmitoyl-protein thioesterase 1	8663305	Lysosomal targeting of palmitoyl-protein thioesterase.

P51610	HCFC1_HUMAN	Host cell factor 1	10629049	Mutations in host cell factor 1 separate its role in cell proliferation from recruitment of VP16 and LZIP.

Q9LYG9	Y5208_ARATH	Uncharacterized protein At5g12080	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q9Y7Z8	MYO1_SCHPO	Myosin-1	16051179	Role of fission yeast myosin I in organization of sterol-rich membrane domains.

P51970	NDUA8_HUMAN	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

Q9BSI4	TINF2_HUMAN	TERF1-interacting nuclear factor 2	16166375	Shelterin: the protein complex that shapes and safeguards human telomeres.

Q9Z260	CLD8_MOUSE	Claudin-8	10601346	Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins.

Q925Q8	DACH2_MOUSE	Dachshund homolog 2	12130660	Tissue-specific regulation of retinal and pituitary precursor cell proliferation.

Q6Q0C0	TRAF7_HUMAN	E3 ubiquitin-protein ligase TRAF7	15001576	TRAF7 potentiates MEKK3-induced AP1 and CHOP activation and induces apoptosis.

Q9UR27	RM31_SCHPO	60S ribosomal protein L31, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8N264	RHG24_HUMAN	Rho GTPase-activating protein 24	16862148	FilGAP, a Rho- and ROCK-regulated GAP for Rac binds filamin A to control actin remodelling.

P18824	ARM_DROME	Armadillo segment polarity protein	8666669	Distinct cellular and subcellular patterns of expression imply distinct functions for the Drosophila homologues of moesin and the neurofibromatosis 2 tumor suppressor, merlin.

Q02641	CACB1_HUMAN	Voltage-dependent L-type calcium channel subunit beta-1	1385409	Skeletal muscle and brain isoforms of a beta-subunit of human voltage-dependent calcium channels are encoded by a single gene.

P15806	TFE2_MOUSE	Transcription factor E2-alpha	12200424	Cloning and characterization of GRIPE, a novel interacting partner of the transcription factor E12 in developing mouse forebrain.

Q39140	TGA6_ARATH	Transcription factor TGA6	10659709	NPR1 differentially interacts with members of the TGA/OBF family of transcription factors that bind an element of the PR-1 gene required for induction by salicylic acid.

O23249	CKS1_ARATH	Cyclin-dependent kinases regulatory subunit 1	11432958	Identification of novel cyclin-dependent kinases interacting with the CKS1 protein of Arabidopsis.

Q16594	TAF9_HUMAN	Transcription initiation factor TFIID subunit 9	15960975	Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

P09208	INSR_DROME	Insulin-like receptor	8603594	The Drosophila insulin receptor is required for normal growth.

Q9LZX4	FLA10_ARATH	Fasciclin-like arabinogalactan protein 10	12805588	Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis.

Q9FM68	BAM4_ARATH	Inactive beta-amylase 4, chloroplastic	18390594	Beta-AMYLASE4, a noncatalytic protein required for starch breakdown, acts upstream of three active beta-amylases in Arabidopsis chloroplasts.

Q8VDP4	K1967_MOUSE	Protein KIAA1967 homolog	19218236	Inhibition of SUV39H1 methyltransferase activity by DBC1.

Q62761	KC1G1_RAT	Casein kinase I isoform gamma-1	7759525	Casein kinase I gamma subfamily. Molecular cloning, expression, and characterization of three mammalian isoforms and complementation of defects in the Saccharomyces cerevisiae YCK genes.

O14270	FHL1_SCHPO	Fork head transcription factor 1	15777722	Characterisation of two novel fork-head gene homologues of Schizosaccharomyces pombe: their involvement in cell cycle and sexual differentiation.

Q9H4B6	SAV1_HUMAN	Protein salvador homolog 1	19212654	The human WW45 protein enhances MST1-mediated apoptosis in vivo.

Q24211	STNA_DROME	Protein stoned-A	10407025	The stoned proteins regulate synaptic vesicle recycling in the presynaptic terminal.

Q62634	VGLU1_RAT	Vesicular glutamate transporter 1	8202535	Cloning and expression of a cDNA encoding a brain-specific Na(+)- dependent inorganic phosphate cotransporter.

P40937	RFC5_HUMAN	Replication factor C subunit 5	8999859	Replication factor C interacts with the C-terminal side of proliferating cell nuclear antigen.

P52961	NAR1_HUMAN	GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1	7947688	Immunological and structural conservation of mammalian skeletal muscle glycosylphosphatidylinositol-linked ADP-ribosyltransferases.

Q03532	HAS1_YEAST	ATP-dependent RNA helicase HAS1	10684247	The yeast nuclear pore complex: composition, architecture, and transport mechanism.

P32473	ODPB_YEAST	Pyruvate dehydrogenase E1 component subunit beta, mitochondrial	8433986	Characterization of PDH beta 1, the structural gene for the pyruvate dehydrogenase beta subunit from Saccharomyces cerevisiae.

Q62120	JAK2_MOUSE	Tyrosine-protein kinase JAK2	9590174	Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis.

P21274	BMP2_MOUSE	Bone morphogenetic protein 2	17522060	PLAP-1/asporin, a novel negative regulator of periodontal ligament mineralization.

P09119	CDC6_YEAST	Cell division control protein 6	9312054	The Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeast.

Q09003	COIL_XENLA	Coilin	8349728	Identification and characterization of a sphere organelle protein.

P62870	ELOB_RAT	Transcription elongation factor B polypeptide 2	7638163	Positive regulation of general transcription factor SIII by a tailed ubiquitin homolog.

Q62768	UN13A_RAT	Protein unc-13 homolog A	16732694	Structural basis for a Munc13-1 homodimer to Munc13-1/RIM heterodimer switch.

Q9UT76	EI2BB_SCHPO	Probable translation initiation factor eIF-2B subunit beta	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9SZP1	MYB4_ARATH	Transcription repressor MYB4	11080161	Transcriptional repression by AtMYB4 controls production of UV- protecting sunscreens in Arabidopsis.

Q8WY41	NANO1_HUMAN	Nanos homolog 1	12690449	Conservation of a Pumilio-Nanos complex from Drosophila germ plasm to human germ cells.

P04550	PTMS_RAT	Parathymosin	2759245	The primary sequence of the PFK-1 inactivating zinc-binding protein as deduced from cDNA sequencing. Identity of the zinc-binding protein with rat parathymosin.

Q01886	HTS1_COCCA	HC-toxin synthetase	1281482	The cyclic peptide synthetase catalyzing HC-toxin production in the filamentous fungus Cochliobolus carbonum is encoded by a 15.7-kilobase open reading frame.

Q96FF9	CDCA5_HUMAN	Sororin	15837422	Sororin, a substrate of the anaphase-promoting complex, is required for sister chromatid cohesion in vertebrates.

Q96T91	GPHA2_HUMAN	Glycoprotein hormone alpha-2	12089349	Evolution of glycoprotein hormone subunit genes in bilateral metazoa: identification of two novel human glycoprotein hormone subunit family genes, GPA2 and GPB5.

Q13075	BIRC1_HUMAN	Baculoviral IAP repeat-containing protein 1	8552191	Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes.

O15438	MRP3_HUMAN	Canalicular multispecific organic anion transporter 2	9813153	Isolation of a novel human canalicular multispecific organic anion transporter, cMOAT2/MRP3, and its expression in cisplatin-resistant cancer cells with decreased ATP-dependent drug transport.

Q15569	TESK1_HUMAN	Dual specificity testis-specific protein kinase 1	12027893	Human sprouty 4, a new ras antagonist on 5q31, interacts with the dual specificity kinase TESK1.

P38959	VPS41_YEAST	Vacuolar protein sorting-associated protein 41	9111041	Vam2/Vps41p and Vam6/Vps39p are components of a protein complex on the vacuolar membranes and involved in the vacuolar assembly in the yeast Saccharomyces cerevisiae.

Q9TZM3	LRK1_CAEEL	Leucine-rich repeat serine/threonine-protein kinase 1	17346966	LRK-1, a C. elegans PARK8-related kinase, regulates axonal-dendritic polarity of SV proteins.

Q8CFW1	ANO2_MOUSE	Anoctamin-2	19474308	TMEM16B, a novel protein with calcium-dependent chloride channel activity, associates with a presynaptic protein complex in photoreceptor terminals.

O74765	SYPM_SCHPO	Probable prolyl-tRNA synthetase, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P20292	AL5AP_HUMAN	Arachidonate 5-lipoxygenase-activating protein	2300173	Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis.

P32915	SC61A_YEAST	Protein transport protein SEC61	1550957	Protein translocation mutants defective in the insertion of integral membrane proteins into the endoplasmic reticulum.

Q8GY55	TIF4B_ARATH	Protein TIFY 4B	20360743	NINJA connects the co-repressor TOPLESS to jasmonate signalling.

O13712	MUG61_SCHPO	Meiotically up-regulated gene 61 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q08096	RCL1_YEAST	RNA 3'-terminal phosphate cyclase-like protein	11565748	Bms1p, a G-domain-containing protein, associates with Rcl1p and is required for 18S rRNA biogenesis in yeast.

P48775	T23O_HUMAN	Tryptophan 2,3-dioxygenase	8666386	Sequence of human tryptophan 2,3-dioxygenase (TDO2): presence of a glucocorticoid response-like element composed of a GTT repeat and an intronic CCCCT repeat.

P40189	IL6RB_HUMAN	Interleukin-6 receptor subunit beta	2261637	Molecular cloning and expression of an IL-6 signal transducer, gp130.

Q9YGW7	DAZL_DANRE	Deleted in azoospermia-like	10330505	Maternal mRNA localization of zebrafish DAZ-like gene.

O43866	CD5L_HUMAN	CD5 antigen-like	9045627	Molecular cloning, mapping to human chromosome 1 q21-q23, and cell binding characteristics of Spalpha, a new member of the scavenger receptor cysteine-rich (SRCR) family of proteins.

P30748	MOAD_ECOLI	Molybdopterin synthase sulfur carrier subunit	11713534	Mechanism of ubiquitin activation revealed by the structure of a bacterial MoeB-MoaD complex.

P53733	RT19_YEAST	37S ribosomal protein S19, mitochondrial	11278769	Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues.

O74918	RRP45_SCHPO	Exosome complex component rrp45	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q15323	K1H1_HUMAN	Keratin, type I cuticular Ha1	7578244	A cDNA encoding the human type I hair keratin hHal.

Q9EPU5	TNR21_MOUSE	Tumor necrosis factor receptor superfamily member 21	19225519	APP binds DR6 to trigger axon pruning and neuron death via distinct caspases.

O95185	UNC5C_HUMAN	Netrin receptor UNC5C	9782087	Cloning and mapping of the UNC5C gene to human chromosome 4q21-q23.

O00625	PIR_HUMAN	Pirin	9079676	Identification of pirin, a novel highly conserved nuclear protein.

P09739	TNNT3_RAT	Troponin T, fast skeletal muscle	16839517	Differences in myofilament calcium sensitivity in rat psoas fibers reconstituted with troponin T isoforms containing the alpha- and beta- exons.

Q9VC45	ASP_DROME	Protein abnormal spindle	9151690	The Drosophila gene abnormal spindle encodes a novel microtubule- associated protein that associates with the polar regions of the mitotic spindle.

Q04206	TF65_HUMAN	Transcription factor p65	10660609	Inhibition of nuclear factor-kappaB-mediated transcription by association with the amino-terminal enhancer of split, a Groucho- related protein lacking WD40 repeats.

Q54KF7	SIBA_DICDI	Integrin beta-like protein A	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

Q9SCU5	WNK5_ARATH	Probable serine/threonine-protein kinase WNK5	18761494	The plant WNK gene family and regulation of flowering time in Arabidopsis.

Q9BUD6	SPON2_HUMAN	Spondin-2	10512675	Identification of genes (SPON2 and C20orf2) differentially expressed between cancerous and noncancerous lung cells by mRNA differential display.

P06239	LCK_HUMAN	Tyrosine-protein kinase Lck	7852312	p70 phosphorylation and binding to p56lck is an early event in interleukin-2-induced onset of cell cycle progression in T- lymphocytes.

P49662	CASP4_HUMAN	Caspase-4	7797510	Identification and characterization of ICH-2, a novel member of the interleukin-1 beta-converting enzyme family of cysteine proteases.

Q9SCY2	FKBP3_ARATH	FKBP-type peptidyl-prolyl cis-trans isomerase 3, chloroplastic	11719511	Proteome map of the chloroplast lumen of Arabidopsis thaliana.

P38989	SMC2_YEAST	Structural maintenance of chromosomes protein 2	7698648	SMC2, a Saccharomyces cerevisiae gene essential for chromosome segregation and condensation, defines a subgroup within the SMC family.

P0AAC8	ISCA_ECOLI	Iron-binding protein iscA	11319236	Iron-sulfur cluster assembly: characterization of IscA and evidence for a specific and functional complex with ferredoxin.

Q9BUB5	MKNK1_HUMAN	MAP kinase-interacting serine/threonine-protein kinase 1	9878069	Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E.

P57087	JAM2_HUMAN	Junctional adhesion molecule B	10779521	Vascular endothelial junction-associated molecule, a novel member of the immunoglobulin superfamily, is localized to intercellular boundaries of endothelial cells.

Q9Y7Q7	DENN_SCHPO	DENN domain-containing protein C297.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O14734	ACOT8_HUMAN	Acyl-coenzyme A thioesterase 8	10092594	Identification of peroxisomal acyl-CoA thioesterases in yeast and humans.

Q63279	K1C19_RAT	Keratin, type I cytoskeletal 19	15247274	Cloning and characterization of cytokeratins 8 and 19 in adult rat striated muscle. Interaction with the dystrophin glycoprotein complex.

P37639	GADX_ECOLI	HTH-type transcriptional regulator gadX	11976288	Functional characterization and regulation of gadX, a gene encoding an AraC/XylS-like transcriptional activator of the Escherichia coli glutamic acid decarboxylase system.

Q06148	NEJ1_YEAST	Non-homologous end-joining protein 1	11711435	NHEJ regulation by mating type is exercised through a novel protein, Lif2p, essential to the ligase IV pathway.

Q13263	TIF1B_HUMAN	Transcription intermediary factor 1-beta	15882967	The mammalian heterochromatin protein 1 binds diverse nuclear proteins through a common motif that targets the chromoshadow domain.

Q8WTD4	DEF_GLOMM	Defensin-A	11886771	Immunopeptides in the defense reactions of Glossina morsitans to bacterial and Trypanosoma brucei brucei infections.

Q13639	5HT4R_HUMAN	5-hydroxytryptamine receptor 4	9603189	Cloning, expression, and pharmacology of four human 5- hydroxytryptamine 4 receptor isoforms produced by alternative splicing in the carboxyl terminus.

Q5EAK4	TLH1_SCHPO	ATP-dependent DNA helicase tlh1	15591066	Expression of a RecQ helicase homolog affects progression through crisis in fission yeast lacking telomerase.

P87219	SOU1_CANAL	Sorbose reductase SOU1	9560244	Monosomy of a specific chromosome determines L-sorbose utilization: a novel regulatory mechanism in Candida albicans.

Q95RJ9	EBI_DROME	F-box-like/WD repeat-containing protein ebi	10215623	ebi regulates epidermal growth factor receptor signaling pathways in Drosophila.

Q9Y6Z7	COL10_HUMAN	Collectin-10	10224141	Molecular cloning of a novel human collectin from liver (CL-L1).

Q9Y4A8	NF2L3_HUMAN	Nuclear factor erythroid 2-related factor 3	10037736	Molecular cloning and functional characterization of a new Cap'n' collar family transcription factor Nrf3.

Q96JQ0	PCD16_HUMAN	Protocadherin-16	9199196	Multiple cadherins are expressed in human fibroblasts.

P57760	STK16_RAT	Serine/threonine-protein kinase 16	10947953	A novel transcriptional factor with Ser/Thr kinase activity involved in the transforming growth factor (TGF)-beta signalling pathway.

P56178	DLX5_HUMAN	Homeobox protein DLX-5	19497851	DLX5 (distal-less homeobox 5) promotes tumor cell proliferation by transcriptionally regulating MYC.

Q64385	I11RA_MOUSE	Interleukin-11 receptor subunit alpha-1	7957045	Cloning of a murine IL-11 receptor alpha-chain; requirement for gp130 for high affinity binding and signal transduction.

Q2I0E5	PDZD6_XENLA	PDZ domain-containing protein 6	18552847	Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells.

O01422	CSN2_CAEEL	COP9 signalosome complex subunit 2	12781129	Neddylation and deneddylation of CUL-3 is required to target MEI- 1/katanin for degradation at the meiosis-to-mitosis transition in C. elegans.

P11234	RALB_HUMAN	Ras-related protein Ral-B	17875936	Geranylgeranyltransferase I inhibitors target RalB to inhibit anchorage-dependent growth and induce apoptosis and RalA to inhibit anchorage-independent growth.

P32769	HBS1_YEAST	Elongation factor 1 alpha-like protein	11909951	Novel G-protein complex whose requirement is linked to the translational status of the cell.

O14172	MET8_SCHPO	Siroheme biosynthesis protein met8	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P70452	STX4_MOUSE	Syntaxin-4	17548353	Doc2beta is a novel Munc18c-interacting partner and positive effector of syntaxin 4-mediated exocytosis.

P23641	MPCP_YEAST	Mitochondrial phosphate carrier protein	2170848	Isolation and characterization of the gene for a yeast mitochondrial import receptor.

O00445	SYT5_HUMAN	Synaptotagmin-5	9177789	Human synaptotagmin V (SYT5): sequence, genomic structure, and chromosomal location.

Q80WM7	PRS33_MOUSE	Serine protease 33	14583634	Mouse chromosome 17A3.3 contains 13 genes that encode functional tryptic-like serine proteases with distinct tissue and cell expression patterns.

Q9P780	NPL4_SCHPO	Nuclear protein localization protein 4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P36013	MAOM_YEAST	NAD-dependent malic enzyme, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P25963	IKBA_HUMAN	NF-kappa-B inhibitor alpha	17956732	RSUME, a small RWD-containing protein, enhances SUMO conjugation and stabilizes HIF-1alpha during hypoxia.

P18074	ERCC2_HUMAN	TFIIH basal transcription factor complex helicase XPD subunit	2184031	ERCC2: cDNA cloning and molecular characterization of a human nucleotide excision repair gene with high homology to yeast RAD3.

Q9UST5	RRN7_SCHPO	RNA polymerase I-specific transcription initiation factor rrn7	12095692	Characterization of a fission yeast subunit of an RNA polymerase I essential transcription initiation factor, SpRrn7h/TAF(I)68, that bridges yeast and mammals: association with SpRrn11h and the core ribosomal RNA gene promoter.

O15169	AXN1_HUMAN	Axin-1	12192039	I-mfa domain proteins interact with Axin and affect its regulation of the Wnt and c-Jun N-terminal kinase signaling pathways.

P20792	DAF1_CAEEL	Cell surface receptor daf-1	10887089	A Caenorhabditis elegans type I TGF beta receptor can function in the absence of type II kinase to promote larval development.

Q01590	SED5_YEAST	Integral membrane protein SED5	9755865	Gos1p, a Saccharomyces cerevisiae SNARE protein involved in Golgi transport.

Q56WK6	PATL1_ARATH	Patellin-1	20543027	The deubiquitinating enzyme AMSH3 is required for intracellular trafficking and vacuole biogenesis in Arabidopsis thaliana.

O75448	MED24_HUMAN	Mediator of RNA polymerase II transcription subunit 24	12218053	A coregulatory role for the TRAP-mediator complex in androgen receptor-mediated gene expression.

P17261	ERS1_YEAST	Cystine transporter	15885099	ERS1 encodes a functional homologue of the human lysosomal cystine transporter.

P52920	NBP35_YEAST	Cytosolic Fe-S cluster assembly factor NBP35	15728363	The eukaryotic P loop NTPase Nbp35: an essential component of the cytosolic and nuclear iron-sulfur protein assembly machinery.

Q93W54	ICMTB_ARATH	Protein-S-isoprenylcysteine O-methyltransferase B	12472689	Prenylcysteine alpha-carboxyl methyltransferase expression and function in Arabidopsis thaliana.

Q02336	ADA2_YEAST	Transcriptional adapter 2	12446794	The novel SLIK histone acetyltransferase complex functions in the yeast retrograde response pathway.

Q9USJ6	FMNR_SCHPO	NAD(P)H-dependent FMN reductase C4B3.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q16763	UBE2S_HUMAN	Ubiquitin-conjugating enzyme E2 S	20061386	The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.

Q96FZ7	CHMP6_HUMAN	Charged multivesicular body protein 6	18606141	Two distinct modes of ESCRT-III recognition are required for VPS4 functions in lysosomal protein targeting and HIV-1 budding.

Q14162	SREC_HUMAN	Endothelial cells scavenger receptor	9395444	Expression cloning of a novel scavenger receptor from human endothelial cells.

Q9U1S7	PKD2_CAEEL	Polycystin-2	17581863	STAM and Hrs down-regulate ciliary TRP receptors.

O60721	NCKX1_HUMAN	Sodium/potassium/calcium exchanger 1	9478004	cDNA cloning of the human retinal rod Na-Ca + K exchanger: comparison with a revised bovine sequence.

Q9WUF3	C8AP2_MOUSE	CASP8-associated protein 2	10235259	The CED-4-homologous protein FLASH is involved in Fas-mediated activation of caspase-8 during apoptosis.

P39935	IF4F1_YEAST	Eukaryotic initiation factor 4F subunit p150	8336723	TIF4631 and TIF4632: two yeast genes encoding the high-molecular- weight subunits of the cap-binding protein complex (eukaryotic initiation factor 4F) contain an RNA recognition motif-like sequence and carry out an essential function.

Q15911	ZFHX3_HUMAN	Zinc finger homeobox protein 3	14715251	ATBF1 enhances the suppression of STAT3 signaling by interaction with PIAS3.

Q07896	NOC3_YEAST	Nucleolar complex-associated protein 3	11371346	Maturation and intranuclear transport of pre-ribosomes requires Noc proteins.

P11940	PABP1_HUMAN	Polyadenylate-binding protein 1	9582337	The human poly(A)-binding protein 1 shuttles between the nucleus and the cytoplasm.

O15232	MATN3_HUMAN	Matrilin-3	15075323	Interactions between the cartilage oligomeric matrix protein and matrilins. Implications for matrix assembly and the pathogenesis of chondrodysplasias.

O80452	AMPD_ARATH	AMP deaminase	16543243	Membrane association, mechanism of action, and structure of Arabidopsis embryonic factor 1 (FAC1).

Q84JA6	CESA4_ARATH	Cellulose synthase A catalytic subunit 4 [UDP-forming]	12538856	Interactions among three distinct CesA proteins essential for cellulose synthesis.

Q9UKJ0	PILRB_HUMAN	Paired immunoglobulin-like type 2 receptor beta	10660620	PILRalpha, a novel immunoreceptor tyrosine-based inhibitory motif- bearing protein, recruits SHP-1 upon tyrosine phosphorylation and is paired with the truncated counterpart PILRbeta.

Q13242	SRSF9_HUMAN	Serine/arginine-rich splicing factor 9	7556075	Identification and characterization of three members of the human SR family of pre-mRNA splicing factors.

P49821	NDUV1_HUMAN	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

O00268	TAF4_HUMAN	Transcription initiation factor TFIID subunit 4	9192867	Human TAF(II)135 potentiates transcriptional activation by the AF-2s of the retinoic acid, vitamin D3, and thyroid hormone receptors in mammalian cells.

Q8GYD2	MND1_ARATH	Meiotic nuclear division protein 1 homolog	16442857	Atmnd1-delta1 is sensitive to gamma-irradiation and defective in meiotic DNA repair.

O94504	TRX2_SCHPO	Thioredoxin-2, mitochondrial	12020831	Characterization and regulation of a second gene encoding thioredoxin from the fission yeast.

P78559	MAP1A_HUMAN	Microtubule-associated protein 1A	8812494	Human microtubule-associated protein 1a (MAP1A) gene: genomic organization, cDNA sequence, and developmental- and tissue-specific expression.

Q93098	WNT8B_HUMAN	Protein Wnt-8b	9536085	A novel mammalian Wnt gene, WNT8B, shows brain-restricted expression in early development, with sharply delimited expression boundaries in the developing forebrain.

O75461	E2F6_HUMAN	Transcription factor E2F6	15960975	Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

P11930	NUD19_MOUSE	Nucleoside diphosphate-linked moiety X motif 19, mitochondrial	14651853	Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.

Q56WH4	HDT2_ARATH	Histone deacetylase HDT2	12694598	Repression of gene expression by Arabidopsis HD2 histone deacetylases.

Q9SWW6	CESA7_ARATH	Cellulose synthase A catalytic subunit 7 [UDP-forming]	12165296	Structure of cellulose-deficient secondary cell walls from the irx3 mutant of Arabidopsis thaliana.

Q9LY23	IPMKA_ARATH	Inositol polyphosphate multikinase alpha	15618435	A role of Arabidopsis inositol polyphosphate kinase, AtIPK2alpha, in pollen germination and root growth.

Q01813	K6PP_HUMAN	6-phosphofructokinase type C	1834056	Isolation and sequence of a cDNA encoding human platelet phosphofructokinase.

Q99PI8	RTN4R_MOUSE	Reticulon-4 receptor	11201742	Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration.

P30561	AHR_MOUSE	Aryl hydrocarbon receptor	7961644	Dioxin binding activities of polymorphic forms of mouse and human arylhydrocarbon receptors.

Q9UIS9	MBD1_HUMAN	Methyl-CpG-binding domain protein 1	12711603	Methyl-CpG binding domain 1 (MBD1) interacts with the Suv39h1-HP1 heterochromatic complex for DNA methylation-based transcriptional repression.

Q6Q6R3	CRIP3_MOUSE	Cysteine-rich protein 3	11713292	Identification and characterization of thymus LIM protein: targeted disruption reduces thymus cellularity.

P29067	ARRB2_RAT	Beta-arrestin-2	16051150	An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior.

Q9Z2Q7	STX8_RAT	Syntaxin-8	15133481	Combinatorial SNARE complexes with VAMP7 or VAMP8 define different late endocytic fusion events.

Q3TXX4	VGLU1_MOUSE	Vesicular glutamate transporter 1	15103023	An essential role for vesicular glutamate transporter 1 (VGLUT1) in postnatal development and control of quantal size.

Q62132	PTPRR_MOUSE	Receptor-type tyrosine-protein phosphatase R	7832766	A novel receptor-type protein tyrosine phosphatase with a single catalytic domain is specifically expressed in mouse brain.

Q9UKU0	ACSL6_HUMAN	Long-chain-fatty-acid--CoA ligase 6	10548543	Identification and molecular characterization of acyl-CoA synthetase in human red cells and erythroid precursor.

Q60700	M3K12_MOUSE	Mitogen-activated protein kinase kinase kinase 12	8663324	Characterization of dual leucine zipper-bearing kinase, a mixed lineage kinase present in synaptic terminals whose phosphorylation state is regulated by membrane depolarization via calcineurin.

O94573	YGDG_SCHPO	Uncharacterized transcriptional regulatory protein C1773.16c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O75173	ATS4_HUMAN	A disintegrin and metalloproteinase with thrombospondin motifs 4	18718938	Epileptic and developmental disorders of the speech cortex: ligand/receptor interaction of wild-type and mutant SRPX2 with the plasminogen activator receptor uPAR.

Q5JY77	GASP1_HUMAN	G-protein coupled receptor-associated sorting protein 1	15086532	Identification of a novel family of G protein-coupled receptor associated sorting proteins.

Q15435	PP1R7_HUMAN	Protein phosphatase 1 regulatory subunit 7	7498485	Molecular cloning of a human polypeptide related to yeast sds22, a regulator of protein phosphatase-1.

P03897	NU3M_HUMAN	NADH-ubiquinone oxidoreductase chain 3	3921850	Six unidentified reading frames of human mitochondrial DNA encode components of the respiratory-chain NADH dehydrogenase.

Q9Y819	YON8_SCHPO	Transmembrane 9 superfamily protein C1105.08	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12504	RKM4_YEAST	Ribosomal N-lysine methyltransferase 4	14562095	Global analysis of protein localization in budding yeast.

O43543	XRCC2_HUMAN	DNA repair protein XRCC2	9628903	The XRCC2 DNA repair gene from human and mouse encodes a novel member of the recA/RAD51 family.

P40317	SOK1_YEAST	Protein SOK1	8065298	Suppression of a yeast cyclic AMP-dependent protein kinase defect by overexpression of SOK1, a yeast gene exhibiting sequence similarity to a developmentally regulated mouse gene.

O95425	SVIL_HUMAN	Supervillin	9867483	Cloning, characterization, and chromosomal localization of human superillin (SVIL).

P11234	RALB_HUMAN	Ras-related protein Ral-B	7673236	Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity.

Q9NUL3	STAU2_HUMAN	Double-stranded RNA-binding protein Staufen homolog 2	10585778	Identification of a novel homolog of the Drosophila staufen protein in the chromosome 8q13-q21.1 region.

Q93XX4	C2D61_ARATH	C2 domain-containing protein At1g53590	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P16951	ATF2_MOUSE	Cyclic AMP-dependent transcription factor ATF-2	9524124	UTF1, a novel transcriptional coactivator expressed in pluripotent embryonic stem cells and extra-embryonic cells.

Q8IUC6	TCAM1_HUMAN	TIR domain-containing adapter molecule 1	14530355	Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3, in the Toll-like receptor signaling.

Q9ZN78	AFRP_STRGR	A-factor receptor protein	2111804	The A-factor-binding protein of Streptomyces griseus negatively controls streptomycin production and sporulation.

Q9USU3	FBH1_SCHPO	F-box DNA helicase protein 1	15147268	Molecular interactions of fission yeast Skp1 and its role in the DNA damage checkpoint.

P31399	ATP5H_RAT	ATP synthase subunit d, mitochondrial	7509337	The complete amino acid sequence of subunit d of rat liver mitochondrial H(+)-ATP synthase.

Q01581	HMCS1_HUMAN	Hydroxymethylglutaryl-CoA synthase, cytoplasmic	7913309	Human cytoplasmic 3-hydroxy-3-methylglutaryl coenzyme A synthase: expression, purification, and characterization of recombinant wild- type and Cys129 mutant enzymes.

Q60817	NACA_MOUSE	Nascent polypeptide-associated complex subunit alpha	9488445	The alpha chain of the nascent polypeptide-associated complex functions as a transcriptional coactivator.

O00291	HIP1_HUMAN	Huntingtin-interacting protein 1	11007801	Huntingtin interacting protein 1 induces apoptosis via a novel caspase-dependent death effector domain.

Q62910	SYNJ1_RAT	Synaptojanin-1	8552192	A presynaptic inositol-5-phosphatase.

P45432	CSN1_ARATH	COP9 signalosome complex subunit 1	12615944	Characterization of the last subunit of the Arabidopsis COP9 signalosome: implications for the overall structure and origin of the complex.

P35436	NMDE1_MOUSE	Glutamate [NMDA] receptor subunit epsilon-1	17329427	NMDA receptor function and NMDA receptor-dependent phosphorylation of huntingtin is altered by the endocytic protein HIP1.

P21127	CD11B_HUMAN	Cell division protein kinase 11B	8195233	Molecular cloning and expression of alternatively spliced PITSLRE protein kinase isoforms.

P48047	ATPO_HUMAN	ATP synthase subunit O, mitochondrial	7490082	Cloning of the cDNA for the human ATP synthase OSCP subunit (ATP5O) by exon trapping and mapping to chromosome 21q22.1-q22.2.

Q02556	IRF8_HUMAN	Interferon regulatory factor 8	1460054	Human interferon consensus sequence binding protein is a negative regulator of enhancer elements common to interferon-inducible genes.

P01129	CDC10_SCHPO	Start control protein cdc10	4018034	Cloning, sequencing and transcriptional control of the Schizosaccharomyces pombe cdc10 'start' gene.

P0AAI3	FTSH_ECOLI	ATP-dependent zinc metalloprotease FtsH	8444797	Topology and subcellular localization of FtsH protein in Escherichia coli.

Q12420	SNU66_YEAST	66 kDa U4/U6.U5 small nuclear ribonucleoprotein component	10449419	Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6.U5] tri-snRNP.

Q99871	HAUS7_HUMAN	HAUS augmin-like complex subunit 7	19427217	HAUS, the 8-subunit human augmin complex, regulates centrosome and spindle integrity.

P22756	GRIK1_RAT	Glutamate receptor, ionotropic kainate 1	16540562	Crystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists.

P06213	INSR_HUMAN	Insulin receptor	11374898	Cloning, mapping, and characterization of the human sorbin and SH3 domain containing 1 (SORBS1) gene: a protein associated with c-Abl during insulin signaling in the hepatoma cell line Hep3B.

P53767	VGFR1_RAT	Vascular endothelial growth factor receptor 1	8058332	A new communication system between hepatocytes and sinusoidal endothelial cells in liver through vascular endothelial growth factor and Flt tyrosine kinase receptor family (Flt-1 and KDR/Flk-1).

O15498	YKT6_HUMAN	Synaptobrevin homolog YKT6	15479160	The human SNARE protein Ykt6 mediates its own palmitoylation at C- terminal cysteine residues.

P40763	STAT3_HUMAN	Signal transducer and activator of transcription 3	7512451	Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91- related transcription factor involved in the gp130-mediated signaling pathway.

Q96RN1	S26A8_HUMAN	Testis anion transporter 1	11278976	Tat1, a novel sulfate transporter specifically expressed in human male germ cells and potentially linked to rhogtpase signaling.

P49454	CENPF_HUMAN	Centromere protein F	7542657	CENP-F is a protein of the nuclear matrix that assembles onto kinetochores at late G2 and is rapidly degraded after mitosis.

Q9N5D6	UNC62_CAEEL	Homeobox protein unc-62	15750187	The roles of two C. elegans HOX co-factor orthologs in cell migration and vulva development.

Q03691	ROT1_YEAST	Protein ROT1	14562095	Global analysis of protein localization in budding yeast.

Q9NX70	MED29_HUMAN	Mediator of RNA polymerase II transcription subunit 29	14576168	A mammalian homolog of Drosophila melanogaster transcriptional coactivator intersex is a subunit of the mammalian Mediator complex.

O75460	ERN1_HUMAN	Serine/threonine-protein kinase/endoribonuclease IRE1	12637535	Structure and intermolecular interactions of the luminal dimerization domain of human IRE1alpha.

Q04360	EB2_EBVB9	mRNA export factor EB2	16129689	Interaction of the Epstein-Barr virus mRNA export factor EB2 with human Spen proteins SHARP, OTT1, and a novel member of the family, OTT3, links Spen proteins with splicing regulation and mRNA export.

Q17941	AKT1_CAEEL	Serine/threonine-protein kinase akt-1	18358814	Direct inhibition of the longevity-promoting factor SKN-1 by insulin- like signaling in C. elegans.

P35000	VIPR2_RAT	Vasoactive intestinal polypeptide receptor 2	8224221	The VIP2 receptor: molecular characterisation of a cDNA encoding a novel receptor for vasoactive intestinal peptide.

Q03654	CEF1_YEAST	Pre-mRNA-splicing factor CEF1	11884590	Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

Q9XFD1	NCBP2_ARATH	Nuclear cap-binding protein subunit 2	19429606	FRIGIDA delays flowering in Arabidopsis via a cotranscriptional mechanism involving direct interaction with the nuclear cap-binding complex.

O00487	PSDE_HUMAN	26S proteasome non-ATPase regulatory subunit 14	19214193	K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC- associated Brcc36 and proteasomal Poh1.

P36629	U2AF2_SCHPO	Splicing factor U2AF 59 kDa subunit	8657565	The small subunit of the splicing factor U2AF is conserved in fission yeast.

Q07646	MEST_MOUSE	Mesoderm-specific transcript protein	18644838	Mesoderm-specific transcript is associated with fat mass expansion in response to a positive energy balance.

Q9LTR9	NMT1_ARATH	Glycylpeptide N-tetradecanoyltransferase 1	10734119	Molecular cloning, genomic organization, and biochemical characterization of myristoyl-CoA:protein N-myristoyltransferase from Arabidopsis thaliana.

Q9USR3	STT4_SCHPO	Phosphatidylinositol 4-kinase stt4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O94566	MU184_SCHPO	Meiotically up-regulated gene 184 protein	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

Q9LYT3	TT12_ARATH	Protein TRANSPARENT TESTA 12	11283341	The TRANSPARENT TESTA12 gene of Arabidopsis encodes a multidrug secondary transporter-like protein required for flavonoid sequestration in vacuoles of the seed coat endothelium.

Q6IN01	PPR3B_RAT	Protein phosphatase 1 regulatory subunit 3B	7498521	Amino acid sequence and expression of the hepatic glycogen-binding (GL)-subunit of protein phosphatase-1.

Q9SW96	SYNC1_ARATH	Asparaginyl-tRNA synthetase, cytoplasmic 1	10824085	Duplication and quadruplication of Arabidopsis thaliana cysteinyl- and asparaginyl-tRNA synthetase genes of organellar origin.

Q9UJS0	CMC2_HUMAN	Calcium-binding mitochondrial carrier protein Aralar2	11566871	Citrin and aralar1 are Ca(2+)-stimulated aspartate/glutamate transporters in mitochondria.

P50947	PHO23_YEAST	Transcriptional regulatory protein PHO23	12672825	Opposite role of yeast ING family members in p53-dependent transcriptional activation.

Q02721	RE102_YEAST	Meiotic recombination protein REC102	15044957	Spatial organization and dynamics of the association of Rec102 and Rec104 with meiotic chromosomes.

P38274	HSL7_YEAST	Protein arginine N-methyltransferase HSL7	10411908	Hsl7p, a negative regulator of Ste20p protein kinase in the Saccharomyces cerevisiae filamentous growth-signaling pathway.

Q60587	ECHB_RAT	Trifunctional enzyme subunit beta, mitochondrial	1730633	Novel fatty acid beta-oxidation enzymes in rat liver mitochondria. II. Purification and properties of enoyl-coenzyme A (CoA) hydratase/3- hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase trifunctional protein.

P11274	BCR_HUMAN	Breakpoint cluster region protein	1903516	Bcr encodes a GTPase-activating protein for p21rac.

P13001	BIOH_ECOLI	Carboxylesterase BioH	12732651	Integrating structure, bioinformatics, and enzymology to discover function: BioH, a new carboxylesterase from Escherichia coli.

P53753	ENG1_YEAST	Endo-1,3(4)-beta-glucanase 1	12455695	Eng1p, an endo-1,3-beta-glucanase localized at the daughter side of the septum, is involved in cell separation in Saccharomyces cerevisiae.

Q6GYP7	RGPA1_MOUSE	Ral GTPase-activating protein subunit alpha-1	12200424	Cloning and characterization of GRIPE, a novel interacting partner of the transcription factor E12 in developing mouse forebrain.

Q9H3P2	NELFA_HUMAN	Negative elongation factor A	10409432	Comparative analysis of a novel gene from the Wolf-Hirschhorn/Pitt- Rogers-Danks syndrome critical region.

O95456	PSMG1_HUMAN	Proteasome assembly chaperone 1	15590417	DSCR2, a Down syndrome critical region protein, is localized to the endoplasmic reticulum of mammalian cells.

P49335	PO3F4_HUMAN	POU domain, class 3, transcription factor 4	7839145	Association between X-linked mixed deafness and mutations in the POU domain gene POU3F4.

Q9FEF8	FBRL1_ARATH	rRNA 2'-O-methyltransferase fibrillarin 1	10829025	Fibrillarin genes encode both a conserved nucleolar protein and a novel small nucleolar RNA involved in ribosomal RNA methylation in Arabidopsis thaliana.

Q96RE7	NACC1_HUMAN	Nucleus accumbens-associated protein 1	17804717	NAC-1 controls cell growth and survival by repressing transcription of Gadd45GIP1, a candidate tumor suppressor.

P22219	VPS15_YEAST	Serine/threonine-protein kinase VPS15	8649377	The newly identified yeast GRD genes are required for retention of late-Golgi membrane proteins.

Q9US02	SDHF1_SCHPO	Succinate dehydrogenase assembly factor 1 homolog, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P76474	ARNF_ECOLI	Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF	17928292	An undecaprenyl phosphate-aminoarabinose flippase required for polymyxin resistance in Escherichia coli.

P51646	ARL5A_RAT	ADP-ribosylation factor-like protein 5A	8765741	Cloning of a novel member (ARL5) of the ARF-family of Ras-related GTPases.

O95278	EPM2A_HUMAN	Laforin	14532330	Laforin, the dual-phosphatase responsible for Lafora disease, interacts with R5 (PTG), a regulatory subunit of protein phosphatase-1 that enhances glycogen accumulation.

O15382	BCAT2_HUMAN	Branched-chain-amino-acid aminotransferase, mitochondrial	9165094	Cloning of the rat and human mitochondrial branched chain aminotransferases (BCATm).

Q12114	CHS5_YEAST	Chitin biosynthesis protein CHS5	17000877	Exomer: a coat complex for transport of select membrane proteins from the trans-Golgi network to the plasma membrane in yeast.

P20291	AL5AP_RAT	Arachidonate 5-lipoxygenase-activating protein	2300173	Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis.

P80471	LIPC_SOLTU	Light-induced protein, chloroplastic	9839468	Molecular characterization of CDSP 34, a chloroplastic protein induced by water deficit in Solanum tuberosum L. plants, and regulation of CDSP 34 expression by ABA and high illumination.

Q03525	TMA23_YEAST	Protein TMA23	16702403	Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes.

P35570	IRS1_RAT	Insulin receptor substrate 1	11018022	Cloning and characterization of PHIP, a novel insulin receptor substrate-1 pleckstrin homology domain interacting protein.

Q570C0	TIR1_ARATH	Protein TRANSPORT INHIBITOR RESPONSE 1	10398681	Identification of an SCF ubiquitin-ligase complex required for auxin response in Arabidopsis thaliana.

O50061	RK4_ARATH	50S ribosomal protein L4, chloroplastic	9461586	The nuclear RPL4 gene encodes a chloroplast protein that co-purifies with the T7-like transcription complex as well as plastid ribosomes.

P17301	ITA2_HUMAN	Integrin alpha-2	2545729	The primary structure of the VLA-2/collagen receptor alpha 2 subunit (platelet GPIa): homology to other integrins and the presence of a possible collagen-binding domain.

P83645	GPX2_RAT	Glutathione peroxidase 2	9685647	Selenium-dependent glutathione peroxidase-GI is a major glutathione peroxidase activity in the mucosal epithelium of rodent intestine.

O88559	MEN1_MOUSE	Menin	9824159	Characterization of the mouse Men1 gene and its expression during development.

Q16655	MAR1_HUMAN	Melanoma antigen recognized by T-cells 1	19717472	The ocular albinism type 1 (OA1) G-protein-coupled receptor functions with MART-1 at early stages of melanogenesis to control melanosome identity and composition.

Q9UBK9	UXT_HUMAN	Protein UXT	16221885	UXT is a novel centrosomal protein essential for cell viability.

O94393	PSMD9_SCHPO	Probable 26S proteasome regulatory subunit p27	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P52435	RPB11_HUMAN	DNA-directed RNA polymerase II subunit RPB11-a	10783144	Identification of a novel partner of RNA polymerase II subunit 11, Che-1, which interacts with and affects the growth suppression function of Rb.

Q940M2	AGT21_ARATH	Alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

P06127	CD5_HUMAN	T-cell surface glycoprotein CD5	1711157	The B-cell surface protein CD72/Lyb-2 is the ligand for CD5.

Q38846	ERS1_ARATH	Ethylene response sensor 1	18577522	Heteromeric interactions among ethylene receptors mediate signaling in Arabidopsis.

Q9VJD3	COG5_DROME	Conserved oligomeric Golgi complex subunit 5	12529436	The Drosophila Cog5 homologue is required for cytokinesis, cell elongation, and assembly of specialized Golgi architecture during spermatogenesis.

Q16555	DPYL2_HUMAN	Dihydropyrimidinase-related protein 2	8973361	A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution.

P50148	GNAQ_HUMAN	Guanine nucleotide-binding protein G(q) subunit alpha	18672896	Regulation of G protein-coupled receptor activities by the platelet- endothelial cell adhesion molecule, PECAM-1.

P87108	TIM10_YEAST	Mitochondrial import inner membrane translocase subunit TIM10	12138093	Assembly of Tim9 and Tim10 into a functional chaperone.

P40069	IMB4_YEAST	Importin subunit beta-4	9182759	A distinct nuclear import pathway used by ribosomal proteins.

Q4LCT0	TXA8_ANDAU	Beta-toxin KAaH1	15656785	A new type of scorpion Na+-channel-toxin-like polypeptide active on K+ channels.

Q9JII9	CXCR3_RAT	C-X-C chemokine receptor type 3	10825390	Identification and molecular characterization of rat CXCR3: receptor expression and interferon-inducible protein-10 binding are increased in focal stroke.

Q9Y673	ALG5_HUMAN	Dolichyl-phosphate beta-glucosyltransferase	10359825	A mutation in the human ortholog of the Saccharomyces cerevisiae ALG6 gene causes carbohydrate-deficient glycoprotein syndrome type-Ic.

P93015	SPL3_ARATH	Squamosa promoter-binding-like protein 3	9301089	Functional analysis of the Arabidopsis thaliana SBP-box gene SPL3: a novel gene involved in the floral transition.

Q54UC0	PRKDC_DICDI	DNA-dependent protein kinase catalytic subunit	16243037	DNA-PKcs-dependent signaling of DNA damage in Dictyostelium discoideum.

P56702	DBIL5_RAT	Diazepam-binding inhibitor-like 5	10415332	Rat endozepine-like peptide (ELP): cDNA cloning, genomic organization and tissue-specific expression.

Q8TFG6	PPK18_SCHPO	Serine/threonine-protein kinase ppk18	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P63098	CANB1_HUMAN	Calcineurin subunit B type 1	2558868	Isolation and sequence of a cDNA clone for human calcineurin B, the Ca2+-binding subunit of the Ca2+/calmodulin-stimulated protein phosphatase.

Q38897	BEL1_ARATH	Homeobox protein BEL1 homolog	8521490	The BELL1 gene encodes a homeodomain protein involved in pattern formation in the Arabidopsis ovule primordium.

Q13275	SEM3F_HUMAN	Semaphorin-3F	8786119	Isolation of the human semaphorin III/F gene (SEMA3F) at chromosome 3p21, a region deleted in lung cancer.

Q6ZXA0	SIA8A_XENLA	Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase	18095347	Cloning and functional characterization of two key enzymes of glycosphingolipid biosynthesis in the amphibian Xenopus laevis.

Q04891	SOX13_MOUSE	Transcription factor SOX-13	9524265	Cloning and characterization of mouse mSox13 cDNA.

Q12461	PTPA2_YEAST	Serine/threonine-protein phosphatase 2A activator 2	11262194	The Saccharomyces cerevisiae phosphotyrosyl phosphatase activator proteins are required for a subset of the functions disrupted by protein phosphatase 2A mutations.

P25694	CDC48_YEAST	Cell division control protein 48	15258615	Shp1 and Ubx2 are adaptors of Cdc48 involved in ubiquitin-dependent protein degradation.

P20349	JANB_DROME	Sex-regulated protein janus-B	2503707	Transcriptional and posttranscriptional regulation contributes to the sex-regulated expression of two sequence-related genes at the janus locus of Drosophila melanogaster.

Q8K4N3	DFB12_MOUSE	Beta-defensin 12	12193721	Identification of multiple novel epididymis-specific beta-defensin isoforms in humans and mice.

Q92357	CFR1_SCHPO	Cell fusion protein cfr1	16598689	The Schizosaccharomyces pombe cfr1(+) gene participates in mating through a new pathway that is independent of fus1(+).

O94315	YH5B_SCHPO	Uncharacterized oxidoreductase C215.11c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q09711	NCS1_SCHPO	Calcium-binding protein NCS-1	14722091	Fission yeast homolog of neuronal calcium sensor-1 (Ncs1p) regulates sporulation and confers calcium tolerance.

P78424	PO6F2_HUMAN	POU domain, class 6, transcription factor 2	8601806	Retina-derived POU-domain factor-1: a complex POU-domain gene implicated in the development of retinal ganglion and amacrine cells.

P29459	IL12A_HUMAN	Interleukin-12 subunit alpha	16548883	Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection.

Q08417	RSB1_YEAST	Sphingoid long-chain base transporter RSB1	12034738	Identification and characterization of a Saccharomyces cerevisiae gene, RSB1, involved in sphingoid long-chain base release.

P40692	MLH1_HUMAN	DNA mismatch repair protein Mlh1	11429708	HNPCC mutations in the human DNA mismatch repair gene hMLH1 influence assembly of hMutLalpha and hMLH1-hEXO1 complexes.

Q9NQT4	EXOS5_HUMAN	Exosome complex exonuclease RRP46	11110791	Three novel components of the human exosome.

P62491	RB11A_HUMAN	Ras-related protein Rab-11A	15837192	Crystallographic evidence for substrate-assisted GTP hydrolysis by a small GTP binding protein.

P32571	UBP4_YEAST	Ubiquitin carboxyl-terminal hydrolase 4	15326198	Bro1 coordinates deubiquitination in the multivesicular body pathway by recruiting Doa4 to endosomes.

P46781	RS9_HUMAN	40S ribosomal protein S9	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

Q99595	TI17A_HUMAN	Mitochondrial import inner membrane translocase subunit Tim17-A	10339406	Genetic and structural characterization of the human mitochondrial inner membrane translocase.

P20155	ISK2_HUMAN	Serine protease inhibitor Kazal-type 2	8428671	Organization and sequence of the gene encoding the human acrosin- trypsin inhibitor (HUSI-II).

Q04477	SPC24_YEAST	Kinetochore protein SPC24	11266451	The Ndc80p complex from Saccharomyces cerevisiae contains conserved centromere components and has a function in chromosome segregation.

P53198	ERP6_YEAST	Protein ERP6	10359606	Erp1p and Erp2p, partners for Emp24p and Erv25p in a yeast p24 complex.

Q02931	UTP17_YEAST	NET1-associated nuclear protein 1	15489292	RNA polymerase I transcription and pre-rRNA processing are linked by specific SSU processome components.

Q25519	PRP2_MANSE	Phenoloxidase subunit 2	10436935	Immulectin, an inducible C-type lectin from an insect, Manduca sexta, stimulates activation of plasma prophenol oxidase.

O08641	SH3Y1_MOUSE	SH3 domain-containing YSC84-like protein 1	12615363	Gene expression of Sh3d19, a novel adaptor protein with five Src homology 3 domains, in anagen mouse hair follicles.

Q8I7G4	TTC30_CAEEL	Tetratricopeptide repeat protein 30 homolog	16049494	Functional coordination of intraflagellar transport motors.

C0LGH3	Y5614_ARATH	Probable LRR receptor-like serine/threonine-protein kinase At1g56140	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q04996	HAT31_ARATH	Homeobox protein HAT3.1	8106082	HAT3.1, a novel Arabidopsis homeodomain protein containing a conserved cysteine-rich region.

Q9LJI2	CCX3_ARATH	Cation/calcium exchanger 3	18775974	AtCCX3 is an Arabidopsis endomembrane H+ -dependent K+ transporter.

P36596	FDFT_SCHPO	Squalene synthase	8474436	Conservation between human and fungal squalene synthetases: similarities in structure, function, and regulation.

Q9UGH3	S23A2_HUMAN	Solute carrier family 23 member 2	10556521	Cloning and functional characterization of the human sodium-dependent vitamin C transporters hSVCT1 and hSVCT2.

Q8VDB9	S620A_MOUSE	Sodium- and chloride-dependent transporter XTRP3A	15689184	Molecular cloning of the mouse IMINO system: an Na+- and Cl-- dependent proline transporter.

Q9FIH9	CML37_ARATH	Calcium-binding protein CML37	17579812	Developmental and stimulus-induced expression patterns of Arabidopsis calmodulin-like genes CML37, CML38 and CML39.

Q12451	OSH2_YEAST	Oxysterol-binding protein homolog 2	12727870	A conserved ER targeting motif in three families of lipid binding proteins and in Opi1p binds VAP.

Q6MGD0	CUTA_RAT	Protein CutA	10954708	Two distinct proteins are associated with tetrameric acetylcholinesterase on the cell surface.

Q9Y6Q9	NCOA3_HUMAN	Nuclear receptor coactivator 3	9346901	TRAM-1, a novel 160-kDa thyroid hormone receptor activator molecule, exhibits distinct properties from steroid receptor coactivator-1.

Q47005	NAC_ECOLI	Nitrogen assimilation regulatory protein nac	9495755	The nac (nitrogen assimilation control) gene from Escherichia coli.

Q9H1D9	RPC6_HUMAN	DNA-directed RNA polymerase III subunit RPC6	9171375	Three human RNA polymerase III-specific subunits form a subcomplex with a selective function in specific transcription initiation.

P07942	LAMB1_HUMAN	Laminin subunit beta-1	1975589	Structure of the human laminin B1 chain gene.

P20263	PO5F1_MOUSE	POU domain, class 5, transcription factor 1	1690859	New type of POU domain in germ line-specific protein Oct-4.

Q9H251	CAD23_HUMAN	Cadherin-23	15537665	Digenic inheritance of deafness caused by mutations in genes encoding cadherin 23 and protocadherin 15 in mice and humans.

Q8BJS8	MTBP_MOUSE	Mdm2-binding protein	10906133	A novel cellular protein (MTBP) binds to MDM2 and induces a G1 arrest that is suppressed by MDM2.

Q96RL1	UIMC1_HUMAN	BRCA1-A complex subunit RAP80	17525340	Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response.

P17936	IBP3_HUMAN	Insulin-like growth factor-binding protein 3	14561895	Interaction between the Alzheimer's survival peptide humanin and insulin-like growth factor-binding protein 3 regulates cell survival and apoptosis.

P0AAX6	MCBA_ECOLI	Uncharacterized protein mcbA	18309357	Escherichia coli transcription factor YncC (McbR) regulates colanic acid and biofilm formation by repressing expression of periplasmic protein YbiM (McbA).

Q9Y696	CLIC4_HUMAN	Chloride intracellular channel protein 4	17636002	CLIC4 mediates and is required for Ca2+-induced keratinocyte differentiation.

Q14160	SCRIB_HUMAN	Protein scribble homolog	16965391	Human homolog of Drosophila tumor suppressor Scribble negatively regulates cell-cycle progression from G1 to S phase by localizing at the basolateral membrane in epithelial cells.

Q12959	DLG1_HUMAN	Disks large homolog 1	11602598	Pilt, a novel peripheral membrane protein at tight junctions in epithelial cells.

O75346	ZN253_HUMAN	Zinc finger protein 253	10585455	Molecular cloning of six novel Kruppel-like zinc finger genes from hematopoietic cells and identification of a novel transregulatory domain KRNB.

P59824	IRPL1_RAT	Interleukin-1 receptor accessory protein-like 1	17502602	IL1-receptor accessory protein-like 1 (IL1RAPL1), a protein involved in cognitive functions, regulates N-type Ca2+-channel and neurite elongation.

Q2V452	CIPK3_ARATH	CBL-interacting serine/threonine-protein kinase 3	12566581	CIPK3, a calcium sensor-associated protein kinase that regulates abscisic acid and cold signal transduction in Arabidopsis.

O00141	SGK1_HUMAN	Serine/threonine-protein kinase Sgk1	10884438	Deranged transcriptional regulation of cell-volume-sensitive kinase hSGK in diabetic nephropathy.

P35869	AHR_HUMAN	Aryl hydrocarbon receptor	8246913	Cloning and expression of a human Ah receptor cDNA.

P38809	YHP7_YEAST	Uncharacterized protein YHR097C	14562095	Global analysis of protein localization in budding yeast.

P97544	LPP3_RAT	Lipid phosphate phosphohydrolase 3	8939937	The Dri 42 gene, whose expression is upregulated during epithelial differentiation, encodes a novel ER resident transmembrane protein.

Q9UDR5	AASS_HUMAN	Alpha-aminoadipic semialdehyde synthase, mitochondrial	10775527	Identification of the alpha-aminoadipic semialdehyde synthase gene, which is defective in familial hyperlysinemia.

O48682	FH4_ARATH	Formin-like protein 4	16313636	Arabidopsis group Ie formins localize to specific cell membrane domains, interact with actin-binding proteins and cause defects in cell expansion upon aberrant expression.

Q9Z0S1	BPNT1_MOUSE	3'(2'),5'-bisphosphate nucleotidase 1	10224133	Cloning and characterization of a mammalian lithium-sensitive bisphosphate 3'-nucleotidase inhibited by inositol 1,4-bisphosphate.

Q9SIU2	NCBP1_ARATH	Nuclear cap-binding protein subunit 1	12427994	Localization, ion channel regulation, and genetic interactions during abscisic acid signaling of the nuclear mRNA cap-binding protein, ABH1.

Q9NQZ3	DAZ1_HUMAN	Deleted in azoospermia protein 1	11390979	A gene family required for human germ cell development evolved from an ancient meiotic gene conserved in metazoans.

P58959	G39AD_DROME	Putative gustatory receptor 39a, isoform A	10710312	Candidate taste receptors in Drosophila.

Q8L868	E1311_ARATH	Glucan endo-1,3-beta-glucosidase 11	14517339	Proteomic analysis of glycosylphosphatidylinositol-anchored membrane proteins.

O00482	NR5A2_HUMAN	Nuclear receptor subfamily 5 group A member 2	16289203	Crystal structure of the human LRH-1 DBD-DNA complex reveals Ftz-F1 domain positioning is required for receptor activity.

P35913	PDE6B_HUMAN	Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta	8394174	Recessive mutations in the gene encoding the beta-subunit of rod phosphodiesterase in patients with retinitis pigmentosa.

P39677	RRF2M_YEAST	Ribosome-releasing factor 2, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q9P2U7	VGLU1_HUMAN	Vesicular glutamate transporter 1	10820226	Molecular cloning of a novel brain-type Na(+)-dependent inorganic phosphate cotransporter.

Q03104	MSC1_YEAST	Meiotic sister chromatid recombination protein 1	11502169	Yeast mitochondrial dehydrogenases are associated in a supramolecular complex.

Q16236	NF2L2_HUMAN	Nuclear factor erythroid 2-related factor 2	11256947	Characterization of the interaction between the transcription factors human polyamine modulated factor (PMF-1) and NF-E2-related factor 2 (Nrf-2) in the transcriptional regulation of the spermidine/spermine N1-acetyltransferase (SSAT) gene.

Q712K3	UB2R2_HUMAN	Ubiquitin-conjugating enzyme E2 R2	20061386	The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.

P33302	PDR5_YEAST	Pleiotropic ABC efflux transporter of multiple drugs	12469340	Subproteomics: identification of plasma membrane proteins from the yeast Saccharomyces cerevisiae.

Q92731	ESR2_HUMAN	Estrogen receptor beta	8769313	ER beta: identification and characterization of a novel human estrogen receptor.

P78352	DLG4_HUMAN	Disks large homolog 4	10725395	The neuregulin receptor ErbB-4 interacts with PDZ-containing proteins at neuronal synapses.

O54957	LAT_MOUSE	Linker for activation of T-cells family member 1	9489702	LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation.

P33724	CAV1_CANFA	Caveolin-1	7568142	Oligomeric structure of caveolin: implications for caveolae membrane organization.

Q95V55	FOXO_DROME	Forkhead box protein O	16054033	Drosophila Melted modulates FOXO and TOR activity.

Q9VX09	ARP8_DROME	Actin-related protein 8	16618800	A Polycomb group protein complex with sequence-specific DNA-binding and selective methyl-lysine-binding activities.

Q10474	LYS5_SCHPO	L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UT04	YLWD_SCHPO	Uncharacterized protein P8A3.13c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O88545	CSN6_MOUSE	COP9 signalosome complex subunit 6	9707402	The COP9 complex is conserved between plants and mammals and is related to the 26S proteasome regulatory complex.

O00139	KIF2A_HUMAN	Kinesin-like protein KIF2A	18411309	DDA3 recruits microtubule depolymerase Kif2a to spindle poles and controls spindle dynamics and mitotic chromosome movement.

P08107	HSP71_HUMAN	Heat shock 70 kDa protein 1A/1B	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

Q9UNE0	EDAR_HUMAN	Tumor necrosis factor receptor superfamily member EDAR	10431241	Mutations in the human homologue of mouse dl cause autosomal recessive and dominant hypohidrotic ectodermal dysplasia.

Q92730	RND1_HUMAN	Rho-related GTP-binding protein Rho6	11095956	Rnd1, a novel rho family GTPase, induces the formation of neuritic processes in PC12 cells.

Q12463	TRM11_YEAST	tRNA guanosine-2'-O-methyltransferase TRM11	14562095	Global analysis of protein localization in budding yeast.

Q9QZH4	AAKB2_RAT	5'-AMP-activated protein kinase subunit beta-2	10544261	Expression of the AMP-activated protein kinase beta1 and beta2 subunits in skeletal muscle.

Q9BQA5	HINFP_HUMAN	Histone H4 transcription factor	17163457	HiNF-P is a bifunctional regulator of cell cycle controlled histone H4 gene transcription.

Q9R1P1	PSB3_MOUSE	Proteasome subunit beta type-3	10436176	The complete primary structure of mouse 20S proteasomes.

Q8T1C6	GNT1_DICDI	[Skp1-protein]-hydroxyproline N-acetylglucosaminyltransferase	10593934	Identification of a UDP-GlcNAc:Skp1-hydroxyproline GlcNAc-transferase in the cytoplasm of Dictyostelium.

P38251	RFC5_YEAST	Replication factor C subunit 5	12604797	Yeast Rad17/Mec3/Ddc1: a sliding clamp for the DNA damage checkpoint.

Q08965	BMS1_YEAST	Ribosome biogenesis protein BMS1	11565749	Bms1p, a novel GTP-binding protein, and the related Tsr1p are required for distinct steps of 40S ribosome biogenesis in yeast.

Q8IXM2	CQ049_HUMAN	MLL1/MLL complex subunit C17orf49	15960975	Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

P19876	CXCL3_HUMAN	C-X-C motif chemokine 3	10095777	Isolation of the CXC chemokines ENA-78, GRO alpha and GRO gamma from tumor cells and leukocytes reveals NH2-terminal heterogeneity. Functional comparison of different natural isoforms.

P40094	COG3_YEAST	Conserved oligomeric Golgi complex subunit 3	11703943	The Sec34/35 Golgi transport complex is related to the exocyst, defining a family of complexes involved in multiple steps of membrane traffic.

Q9HCK4	ROBO2_HUMAN	Roundabout homolog 2	17357069	Disruption of ROBO2 is associated with urinary tract anomalies and confers risk of vesicoureteral reflux.

P92935	TLC2_ARATH	ADP,ATP carrier protein 2, chloroplastic	12766230	Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.

O08726	GALR2_RAT	Galanin receptor type 2	9427506	Cloning, pharmacological characterization and distribution of a novel galanin receptor.

P42945	UTP10_YEAST	U3 small nucleolar RNA-associated protein 10	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Q9Y297	FBW1A_HUMAN	F-box/WD repeat-containing protein 1A	9660940	A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif.

P41208	CETN2_HUMAN	Centrin-2	8248209	Molecular cloning and centrosomal localization of human caltractin.

P05000	IFNW1_HUMAN	Interferon omega-1	1647209	Human interferon omega 1: isolation of the gene, expression in Chinese hamster ovary cells and characterization of the recombinant protein.

Q9U720	DCSA_DICDI	Cellulose synthase catalytic subunit A [UDP-forming]	10681463	The cellulose synthase gene of Dictyostelium.

Q8CE90	MP2K7_MOUSE	Dual specificity mitogen-activated protein kinase kinase 7	9405446	Activation of stress-activated protein kinases/c-Jun N-terminal protein kinases (SAPKs/JNKs) by a novel mitogen-activated protein kinase kinase (MKK7).

P51996	YPT32_YEAST	GTP-binding protein YPT32/YPT11	11943201	Identification of the novel proteins Yip4p and Yip5p as Rab GTPase interacting factors.

P80471	LIPC_SOLTU	Light-induced protein, chloroplastic	8717138	Characterization of a novel drought-induced 34-kDa protein located in the thylakoids of Solanum tuberosum L. plants.

Q9NRR6	INP5E_HUMAN	72 kDa inositol polyphosphate 5-phosphatase	19668215	INPP5E mutations cause primary cilium signaling defects, ciliary instability and ciliopathies in human and mouse.

O02482	UNC37_CAEEL	Transcription factor unc-37	10557206	UNC-4/UNC-37-dependent repression of motor neuron-specific genes controls synaptic choice in Caenorhabditis elegans.

P34166	MFA2_YEAST	Mating hormone A-factor 2	3285180	The a-factor pheromone of Saccharomyces cerevisiae is essential for mating.

O76906	CRM_DROME	Protein cramped	9310333	The cramped gene of Drosophila is a member of the Polycomb-group, and interacts with mus209, the gene encoding Proliferating Cell Nuclear Antigen.

P49598	P2C37_ARATH	Protein phosphatase 2C 37	16214899	The Arabidopsis cold-responsive transcriptome and its regulation by ICE1.

Q54M25	PONB_DICDI	Ponticulin-like protein B	12890554	Identification of a second member of the ponticulin gene family and its differential expression pattern.

P04426	WNT1_MOUSE	Proto-oncogene Wnt-1	19841259	Reciprocal regulation of Wnt and Gpr177/mouse Wntless is required for embryonic axis formation.

Q63768	CRK_RAT	Adapter molecule crk	8901553	CrkII signals from epidermal growth factor receptor to Ras.

P38263	VID24_YEAST	Vacuolar import and degradation protein 24	9508768	Vid24p, a novel protein localized to the fructose-1, 6- bisphosphatase-containing vesicles, regulates targeting of fructose- 1,6-bisphosphatase from the vesicles to the vacuole for degradation.

P04554	PRM2_HUMAN	Protamine-2	2081589	Genomic sequences of human protamines whose genes, PRM1 and PRM2, are clustered.

Q94AH6	CUL1_ARATH	Cullin-1	12058059	Null mutation of AtCUL1 causes arrest in early embryogenesis in Arabidopsis.

Q80Z96	VANG1_MOUSE	Vang-like protein 1	15456783	Independent mutations in mouse Vangl2 that cause neural tube defects in looptail mice impair interaction with members of the Dishevelled family.

P15391	CD19_HUMAN	B-lymphocyte antigen CD19	2472450	Isolation of cDNAs encoding the CD19 antigen of human and mouse B lymphocytes. A new member of the immunoglobulin superfamily.

P56945	BCAR1_HUMAN	Breast cancer anti-estrogen resistance protein 1	10639512	BCAR1, a human homologue of the adapter protein p130Cas, induces anti-estrogen resistance in breast cancer cells.

Q06160	SPH1_YEAST	Protein SPH1	9214378	A small conserved domain in the yeast Spa2p is necessary and sufficient for its polarized localization.

O74867	YQ9H_SCHPO	Uncharacterized protein C18.17c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q92932	PTPR2_HUMAN	Receptor-type tyrosine-protein phosphatase N2	8798755	Cloning and characterization of islet cell antigen-related protein- tyrosine phosphatase (PTP), a novel receptor-like PTP and autoantigen in insulin-dependent diabetes.

Q02108	GCYA3_HUMAN	Guanylate cyclase soluble subunit alpha-3	9742212	Human soluble guanylate cyclase: functional expression and revised isoenzyme family.

Q10953	WRM1_CAEEL	Armadillo repeat-containing protein wrm-1	9288750	Wnt signaling and an APC-related gene specify endoderm in early C. elegans embryos.

Q9Y7U6	RGF1_SCHPO	Rho1 guanine nucleotide exchange factor 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Z1G3	VATC1_MOUSE	V-type proton ATPase subunit C 1	12527205	Diversity of mouse proton-translocating ATPase: presence of multiple isoforms of the C, d and G subunits.

P54216	ALF1_CAEEL	Fructose-bisphosphate aldolase 1	9056253	Caenorhabditis elegans has two isozymic forms, CE-1 and CE-2, of fructose-1,6-bisphosphate aldolase which are encoded by different genes.

Q8VD46	ASZ1_MOUSE	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1	12040005	Identification of Gasz, an evolutionarily conserved gene expressed exclusively in germ cells and encoding a protein with four ankyrin repeats, a sterile-alpha motif, and a basic leucine zipper.

Q02485	CAC1S_RAT	Voltage-dependent L-type calcium channel subunit alpha-1S	7479909	Multiple calcium channel transcripts in rat osteosarcoma cells: selective activation of alpha 1D isoform by parathyroid hormone.

P04764	ENOA_RAT	Alpha-enolase	15041191	Localization of enolase in synaptic plasma membrane as an alphagamma heterodimer in rat brain.

P40438	VTH1_YEAST	Protein VTH1	14562095	Global analysis of protein localization in budding yeast.

Q9EPW2	KLF15_MOUSE	Krueppel-like factor 15	12097321	The Kruppel-like factor KLF15 regulates the insulin-sensitive glucose transporter GLUT4.

Q9YHC5	FOXG1_XENLA	Forkhead box protein G1	9811573	XBF-1, a winged helix transcription factor with dual activity, has a role in positioning neurogenesis in Xenopus competent ectoderm.

P01241	SOMA_HUMAN	Somatotropin	1549776	Human growth hormone and extracellular domain of its receptor: crystal structure of the complex.

Q8R1P4	ATG10_MOUSE	Ubiquitin-like-conjugating enzyme ATG10	12482611	Mouse Apg10 as an Apg12-conjugating enzyme: analysis by the conjugation-mediated yeast two-hybrid method.

Q02846	GUC2D_HUMAN	Retinal guanylyl cyclase 1	1356371	Molecular cloning of a retina-specific membrane guanylyl cyclase.

P09208	INSR_DROME	Insulin-like receptor	2454394	Tissue localization of Drosophila melanogaster insulin receptor transcripts during development.

P24135	PLCG2_RAT	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2	2557343	A second type of rat phosphoinositide-specific phospholipase C containing a src-related sequence not essential for phosphoinositide- hydrolyzing activity.

Q8KBL4	RBLL_CHLTE	Ribulose bisphosphate carboxylase-like protein	11287671	A ribulose-1,5-bisphosphate carboxylase/oxygenase (RubisCO)-like protein from Chlorobium tepidum that is involved with sulfur metabolism and the response to oxidative stress.

Q12798	CETN1_HUMAN	Centrin-1	8175926	Cloning of a cDNA encoding human centrin, an EF-hand protein of centrosomes and mitotic spindle poles.

Q12350	JID1_YEAST	J domain-containing protein 1	14562095	Global analysis of protein localization in budding yeast.

Q0Q029	DFP1_ANTMY	Putative defense protein 1	16857061	Analysis of bacteria-challenged wild silkmoth, Antheraea mylitta (lepidoptera) transcriptome reveals potential immune genes.

P84737	PALFB_EUGGR	Photoactivated adenylate cyclase subunit alpha-like protein FB	16121285	Photoactivated adenylyl cyclase (PAC) genes in the flagellate Euglena gracilis mutant strains.

Q7TQD2	TPPP_MOUSE	Tubulin polymerization-promoting protein	18028908	The phosphorylation of p25/TPPP by LIM kinase 1 inhibits its ability to assemble microtubules.

P78556	CCL20_HUMAN	C-C motif chemokine 20	9129037	Cloning and characterization of Exodus, a novel beta-chemokine.

P97440	SLBP_MOUSE	Histone RNA hairpin-binding protein	19470752	Three proteins of the U7-specific Sm ring function as the molecular ruler to determine the site of 3'-end processing in mammalian histone pre-mRNA.

Q12799	TCP10_HUMAN	T-complex protein 10A homolog	8111376	The human homolog of a candidate mouse t complex responder gene: conserved motifs and evolution with punctuated equilibria.

P53062	BRR6_YEAST	Nucleus export protein BRR6	11483521	An essential nuclear envelope integral membrane protein, Brr6p, required for nuclear transport.

P30043	BLVRB_HUMAN	Flavin reductase	7929092	Biliverdin-IX alpha reductase and biliverdin-IX beta reductase from human liver. Purification and characterization.

Q869V1	NRAM1_DICDI	Metal transporter nramp1 homolog	16445684	Function and mechanism of action of Dictyostelium Nramp1 (Slc11a1) in bacterial infection.

Q9NYR8	RDH8_HUMAN	Retinol dehydrogenase 8	10753906	Identification and characterization of all-trans-retinol dehydrogenase from photoreceptor outer segments, the visual cycle enzyme that reduces all-trans-retinal to all-trans-retinol.

Q06162	NKP2_YEAST	Central kinetochore subunit NKP2	14562095	Global analysis of protein localization in budding yeast.

Q96SN8	CK5P2_HUMAN	CDK5 regulatory subunit-associated protein 2	10721722	Cloning of three novel neuronal Cdk5 activator binding proteins.

Q9UJM8	HAOX1_HUMAN	Hydroxyacid oxidase 1	10777549	Identification and characterization of HAOX1, HAOX2, and HAOX3, three human peroxisomal 2-hydroxy acid oxidases.

P13679	SC11C_CANFA	Signal peptidase complex catalytic subunit SEC11C	3511473	Purification of microsomal signal peptidase as a complex.

P10719	ATPB_RAT	ATP synthase subunit beta, mitochondrial	8764999	Mitochondrial ATP synthase F1-beta-subunit is a calcium-binding protein.

P48523	CADH4_ARATH	Cinnamyl alcohol dehydrogenase 4	14745009	Functional reclassification of the putative cinnamyl alcohol dehydrogenase multigene family in Arabidopsis.

O14113	YEJI_SCHPO	UPF0667 family protein C31G5.18c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O94308	CSN1_SCHPO	COP9 signalosome complex subunit 1	12695334	Cop9/signalosome subunits and Pcu4 regulate ribonucleotide reductase by both checkpoint-dependent and -independent mechanisms.

Q8CI19	PDGFC_MOUSE	Platelet-derived growth factor C	10806482	PDGF-C is a new protease-activated ligand for the PDGF alpha- receptor.

O14920	IKKB_HUMAN	Inhibitor of nuclear factor kappa-B kinase subunit beta	9813230	IkappaB kinase-alpha and -beta genes are coexpressed in adult and embryonic tissues but localized to different human chromosomes.

P41586	PACR_HUMAN	Pituitary adenylate cyclase-activating polypeptide type I receptor	7902709	Molecular cloning and functional expression of a cDNA encoding a human pituitary adenylate cyclase activating polypeptide receptor.

Q13156	RFA4_HUMAN	Replication protein A 30 kDa subunit	7760808	Rpa4, a homolog of the 34-kilodalton subunit of the replication protein A complex.

P46416	GSHB_ARATH	Glutathione synthetase, chloroplastic	8612643	Cloning of Arabidopsis thaliana glutathione synthetase (GSH2) by functional complementation of a yeast gsh2 mutant.

P36523	RM15_YEAST	54S ribosomal protein L15, mitochondrial	9151978	Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae.

Q27403	GCM_DROME	Transcription factor glial cells missing	7553843	Glial cells missing: a genetic switch that controls glial versus neuronal fate.

Q12154	GET3_YEAST	ATPase GET3	16260785	The yeast Arr4p ATPase binds the chloride transporter Gef1p when copper is available in the cytosol.

Q02710	ECM23_YEAST	Protein ECM23	11889490	The SRD2 gene is involved in Saccharomyces cerevisiae morphogenesis.

Q6TXD4	DNMBP_MOUSE	Dynamin-binding protein	14506234	Tuba, a novel protein containing bin/amphiphysin/Rvs and Dbl homology domains, links dynamin to regulation of the actin cytoskeleton.

Q02205	MEH1_YEAST	Protein MEH1	15989961	The TOR and EGO protein complexes orchestrate microautophagy in yeast.

P41005	MES1_SCHPO	Protein mes1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9H0P0	5NT3_HUMAN	Cytosolic 5'-nucleotidase 3	10942414	Human erythrocyte pyrimidine 5'-nucleotidase, PN-I, is identical to p36, a protein associated to lupus inclusion formation in response to alpha-interferon.

O02228	SC5A7_CAEEL	High-affinity choline transporter 1	10649566	Identification and characterization of the high-affinity choline transporter.

Q13415	ORC1_HUMAN	Origin recognition complex subunit 1	7502077	Conserved initiator proteins in eukaryotes.

O75698	HUG1_HUMAN	Protein HUG-1	10393251	Sequence of 10q24 locus surrounding the HOX11 oncogene reveals a new gene HUG1 expressed in a T-ALL cell line.

Q13822	ENPP2_HUMAN	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	8586446	Molecular cloning and chromosomal assignment of the human brain-type phosphodiesterase I/nucleotide pyrophosphatase gene (PDNP2).

O43683	BUB1_HUMAN	Mitotic checkpoint serine/threonine-protein kinase BUB1	10198256	Phosphorylation of human MAD1 by the BUB1 kinase in vitro.

P01730	CD4_HUMAN	T-cell surface glycoprotein CD4	11113139	Cloning of ACP33 as a novel intracellular ligand of CD4.

Q63257	IL4RA_RAT	Interleukin-4 receptor subunit alpha	7640343	The rat interleukin 4 receptor: coevolution of ligand and receptor.

Q07653	HBT1_YEAST	Protein HBT1	11923536	Role of a ubiquitin-like modification in polarized morphogenesis.

P40215	NDH1_YEAST	External NADH-ubiquinone oxidoreductase 1, mitochondrial	9733747	The Saccharomyces cerevisiae NDE1 and NDE2 genes encode separate mitochondrial NADH dehydrogenases catalyzing the oxidation of cytosolic NADH.

Q15848	ADIPO_HUMAN	Adiponectin	10095105	Organization of the gene for gelatin-binding protein (GBP28).

O35316	SC6A6_MOUSE	Sodium- and chloride-dependent taurine transporter	1465453	Cloning and expression of a cDNA encoding the transporter of taurine and beta-alanine in mouse brain.

P49893	WN11B_XENLA	Protein Wnt-11b	19906850	Secreted Frizzled-related proteins enhance the diffusion of Wnt ligands and expand their signalling range.

O88302	GNA15_RAT	Guanine nucleotide-binding protein subunit alpha-15	9685675	Identification of two alpha-subunit species of GTP-binding proteins, G alpha 15 and G alpha q, expressed in rat taste buds.

Q62315	JARD2_MOUSE	Protein Jumonji	19010785	A jumonji (Jarid2) protein complex represses cyclin D1 expression by methylation of histone H3-K9.

P83714	CTF2_MOUSE	Cardiotrophin-2	15051883	Neuropoietin, a new IL-6-related cytokine signaling through the ciliary neurotrophic factor receptor.

Q03345	LIN3_CAEEL	Protein lin-3	1641037	The gene lin-3 encodes an inductive signal for vulval development in C. elegans.

Q96PK6	RBM14_HUMAN	RNA-binding protein 14	11443112	Identification and characterization of RRM-containing coactivator activator (CoAA) as TRBP-interacting protein, and its splice variant as a coactivator modulator (CoAM).

Q91619	NODAL_XENLA	Nodal homolog	10067895	The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals.

P04001	OPSG_HUMAN	Green-sensitive opsin	1302020	Defective colour vision associated with a missense mutation in the human green visual pigment gene.

O35431	APBA2_RAT	Amyloid beta A4 precursor protein-binding family A member 2	9395480	Mints, Munc18-interacting proteins in synaptic vesicle exocytosis.

Q03755	CUT1_CAEEL	Cuticlin-1	1864469	cut-1 a Caenorhabditis elegans gene coding for a dauer-specific noncollagenous component of the cuticle.

O22476	BRI1_ARATH	Protein BRASSINOSTEROID INSENSITIVE 1	12150928	BRI1/BAK1, a receptor kinase pair mediating brassinosteroid signaling.

Q9NZN9	AIPL1_HUMAN	Aryl-hydrocarbon-interacting protein-like 1	12374762	The inherited blindness associated protein AIPL1 interacts with the cell cycle regulator protein NUB1.

O70263	LNX1_MOUSE	E3 ubiquitin-protein ligase LNX	11782429	LNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradation.

Q9P126	CLC1B_HUMAN	C-type lectin domain family 1 member B	10671229	Molecular characterization of two novel C-type lectin-like receptors, one of which is selectively expressed in human dendritic cells.

P10862	RAD18_YEAST	Postreplication repair E3 ubiquitin-protein ligase RAD18	10924462	The Saccharomyces cerevisiae RAD6 group is composed of an error-prone and two error-free postreplication repair pathways.

P29478	SEC65_YEAST	Signal recognition particle subunit SEC65	1313947	SEC65 gene product is a subunit of the yeast signal recognition particle required for its integrity.

Q54XI5	RL9_DICDI	60S ribosomal protein L9	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q8C8N2	SCAI_MOUSE	Protein SCAI	19350017	SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta1-integrin.

P02743	SAMP_HUMAN	Serum amyloid P-component	2987268	Human serum amyloid P component. cDNA isolation, complete sequence of pre-serum amyloid P component, and localization of the gene to chromosome 1.

Q96RJ0	TAAR1_HUMAN	Trace amine-associated receptor 1	15718104	Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors.

P33755	NPL4_YEAST	Nuclear protein localization protein 4	11739805	HRD4/NPL4 is required for the proteasomal processing of ubiquitinated ER proteins.

P47968	RPIA_MOUSE	Ribose-5-phosphate isomerase	7758956	The ribose 5-phosphate isomerase-encoding gene is located immediately downstream from that encoding murine immunoglobulin kappa.

P81918	OR43B_DROME	Odorant receptor 43b	10458908	Identification of candidate Drosophila olfactory receptors from genomic DNA sequence.

P70062	T7L1A_XENLA	Transcription factor 7-like 1-A	9308964	A beta-catenin/XTcf-3 complex binds to the siamois promoter to regulate dorsal axis specification in Xenopus.

P38838	WSS1_YEAST	DNA damage response protein WSS1	11606525	Genes involved in sister chromatid separation and segregation in the budding yeast Saccharomyces cerevisiae.

P84740	PBL9F_EUGGR	Photoactivated adenylate cyclase subunit beta-like protein 1224-5/9F	16121285	Photoactivated adenylyl cyclase (PAC) genes in the flagellate Euglena gracilis mutant strains.

Q9BV73	CP250_HUMAN	Centrosome-associated protein CEP250	18851962	A novel function of CEP135 as a platform protein of C-NAP1 for its centriolar localization.

P84022	SMAD3_HUMAN	Mothers against decapentaplegic homolog 3	12154125	Smad3 allostery links TGF-beta receptor kinase activation to transcriptional control.

P47149	NNF1_YEAST	Kinetochore-associated protein NNF1	14657030	Nsl1p is essential for the establishment of bipolarity and the localization of the Dam-Duo complex.

Q9BXR6	FHR5_HUMAN	Complement factor H-related protein 5	11058592	Human factor H-related protein 5 (FHR-5). A new complement-associated protein.

Q9LK32	Y3721_ARATH	Uncharacterized protein At3g27210	15618630	Identification of three clones which commonly interact with the kinase domains of highly homologous two receptor-like kinases, RLK902 and RKL1.

Q9WUD8	FAIM1_MOUSE	Fas apoptotic inhibitory molecule 1	10075978	A novel gene coding for a Fas apoptosis inhibitory molecule (FAIM) isolated from inducibly Fas-resistant B lymphocytes.

Q9VEU5	GCYDB_DROME	Soluble guanylate cyclase 89Db	15485853	Atypical soluble guanylyl cyclases in Drosophila can function as molecular oxygen sensors.

Q9FGN8	DYAD_ARATH	Protein DYAD	11459834	SWITCH1 (SWI1): a novel protein required for the establishment of sister chromatid cohesion and for bivalent formation at meiosis.

Q9ES52	SHIP1_MOUSE	Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1	10068665	A novel spliced form of SH2-containing inositol phosphatase is expressed during myeloid development.

O61235	CATA2_CAEEL	Catalase-2	10335847	A cytosolic catalase is needed to extend adult lifespan in C. elegans daf-C and clk-1 mutants.

P26284	ODPA_RAT	Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial	8158120	The pyruvate dehydrogenase complex: cloning of the rat somatic E1 alpha subunit and its coordinate expression with the mRNAs for the E1 beta, E2, and E3 catalytic subunits in developing rat brain.

P50085	PHB2_YEAST	Prohibitin-2	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P38960	STN1_YEAST	Protein STN1	11230140	Ten1 functions in telomere end protection and length regulation in association with Stn1 and Cdc13.

O55005	ROBO1_RAT	Roundabout homolog 1	10102268	Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance.

Q04666	HES1_RAT	Transcription factor HES-1	8649374	The WRPW motif of the hairy-related basic helix-loop-helix repressor proteins acts as a 4-amino-acid transcription repression and protein- protein interaction domain.

Q01449	MLRA_HUMAN	Myosin regulatory light chain 2, atrial isoform	1429676	Differential regulation of the atrial isoforms of the myosin light chains during striated muscle development.

Q8VYZ0	ORTH2_ARATH	E3 ubiquitin-protein ligase ORTHRUS 2	17242155	VIM1, a methylcytosine-binding protein required for centromeric heterochromatinization.

P53930	AF9_YEAST	Protein AF-9 homolog	14645854	ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex.

P40348	RFC2_YEAST	Replication factor C subunit 2	11389843	Identification of RFC(Ctf18p, Ctf8p, Dcc1p): an alternative RFC complex required for sister chromatid cohesion in S. cerevisiae.

Q02817	MUC2_HUMAN	Mucin-2	19359471	The protein disulfide isomerase AGR2 is essential for production of intestinal mucus.

P15919	RAG1_MOUSE	V(D)J recombination-activating protein 1	19396172	Structure of the RAG1 nonamer binding domain with DNA reveals a dimer that mediates DNA synapsis.

Q8K1F9	LCTL_MOUSE	Lactase-like protein	12084582	Identification of a novel mouse membrane-bound family 1 glycosidase- like protein, which carries an atypical active site structure.

P22810	HMOC_DROME	Homeotic protein ocelliless	12967559	Otd/Crx, a dual regulator for the specification of ommatidia subtypes in the Drosophila retina.

Q96FV3	TSN17_HUMAN	Tetraspanin-17	10531035	Identification of a family of human F-box proteins.

Q9LNR3	LOX3_ARATH	Lipoxygenase 3, chloroplastic	18156220	Systemic and intracellular responses to photooxidative stress in Arabidopsis.

Q9V460	SPT5H_DROME	Transcription elongation factor SPT5	12490954	The RNA processing exosome is linked to elongating RNA polymerase II in Drosophila.

Q8JIT7	FAST3_XENLA	Forkhead activin signal transducer 3	12050132	A novel Xenopus Smad-interacting forkhead transcription factor (XFast-3) cooperates with XFast-1 in regulating gastrulation movements.

Q16520	BATF_HUMAN	Basic leucine zipper transcriptional factor ATF-like	8630063	SFA-2, a novel bZIP transcription factor induced by human T-cell leukemia virus type I, is highly expressed in mature lymphocytes.

O96020	CCNE2_HUMAN	G1/S-specific cyclin-E2	9840943	Cyclin E2, a novel human G1 cyclin and activating partner of CDK2 and CDK3, is induced by viral oncoproteins.

Q9H1K1	ISCU_HUMAN	Iron-sulfur cluster assembly enzyme ISCU, mitochondrial	11060020	Distinct iron-sulfur cluster assembly complexes exist in the cytosol and mitochondria of human cells.

O61735	CLOCK_DROME	Circadian locomoter output cycles protein kaput	9742131	Circadian regulation of a Drosophila homolog of the mammalian clock gene: PER and TIM function as positive regulators.

Q9NXR7	BRE_HUMAN	BRCA1-A complex subunit BRE	19261746	MERIT40 controls BRCA1-Rap80 complex integrity and recruitment to DNA double-strand breaks.

P63241	IF5A1_HUMAN	Eukaryotic translation initiation factor 5A-1	15371445	A novel eIF5A complex functions as a regulator of p53 and p53- dependent apoptosis.

Q03311	CHLE_MOUSE	Cholinesterase	17212694	Excessive hippocampal acetylcholine levels in acetylcholinesterase- deficient mice are moderated by butyrylcholinesterase activity.

Q96SN8	CK5P2_HUMAN	CDK5 regulatory subunit-associated protein 2	14654843	Proteomic characterization of the human centrosome by protein correlation profiling.

P35053	GPC1_RAT	Glypican-1	8207484	Neuronal expression of glypican, a cell-surface glycosylphosphatidylinositol-anchored heparan sulfate proteoglycan, in the adult rat nervous system.

P84084	ARF5_MOUSE	ADP-ribosylation factor 5	8947846	Structure and intracellular localization of mouse ADP-ribosylation factors type 1 to type 6 (ARF1-ARF6).

Q923E4	SIRT1_MOUSE	NAD-dependent deacetylase sirtuin-1	10693811	Transcriptional silencing and longevity protein Sir2 is an NAD- dependent histone deacetylase.

Q54QQ1	PHG2_DICDI	Serine/threonine-protein kinase phg2	17371831	Rap1 controls cell adhesion and cell motility through the regulation of myosin II.

Q6NLQ8	XB32_ARATH	E3 ubiquitin-protein ligase XBAT32	20511490	Arabidopsis RING E3 ligase XBAT32 regulates lateral root production through its role in ethylene biosynthesis.

Q8CFE6	S38A2_MOUSE	Sodium-coupled neutral amino acid transporter 2	17003038	Regulation of amino acid transporter ATA2 by ubiquitin ligase Nedd4- 2.

P38146	YPT10_YEAST	GTP-binding protein YPT10	11943201	Identification of the novel proteins Yip4p and Yip5p as Rab GTPase interacting factors.

Q9Y490	TLN1_HUMAN	Talin-1	18342854	Identification of a repeated domain within mammalian alpha-synemin that interacts directly with talin.

P80428	ARP4_YEAST	Actin-related protein 4	15610740	Binding of chromatin-modifying activities to phosphorylated histone H2A at DNA damage sites.

Q91620	NOD2A_XENLA	Nodal homolog 2-A	10375512	Xenopus nodal-related signaling is essential for mesendodermal patterning during early embryogenesis.

P38754	RL14B_YEAST	60S ribosomal protein L14-B	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q6URW6	MYH14_MOUSE	Myosin-14	14594953	Identification and characterization of nonmuscle myosin II-C, a new member of the myosin II family.

P05943	S10AA_RAT	Protein S100-A10	3422491	Nerve growth factor induces the genes for two proteins related to a family of calcium-binding proteins in PC12 cells.

P63096	GNAI1_HUMAN	Guanine nucleotide-binding protein G(i) subunit alpha-1	3110783	Human cDNA clones for an alpha subunit of Gi signal-transduction protein.

Q07913	NSE1_YEAST	Non-structural maintenance of chromosomes element 1	15738391	A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization.

O80434	LAC4_ARATH	Laccase-4	15980264	Identification of novel genes in Arabidopsis involved in secondary cell wall formation using expression profiling and reverse genetics.

P23757	POXM_DROME	Paired box pox-meso protein	17942482	A key role of Pox meso in somatic myogenesis of Drosophila.

P32914	SPT4_YEAST	Transcription elongation factor SPT4	9450930	Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae.

Q08646	SSP2_YEAST	Sporulation-specific protein 2	12073037	SSP2, a sporulation-specific gene necessary for outer spore wall assembly in the yeast Saccharomyces cerevisiae.

Q9UJF2	NGAP_HUMAN	Ras GTPase-activating protein nGAP	9877179	A novel human RasGAP-like gene that maps within the prostate cancer susceptibility locus at chromosome 1q25.

Q05431	APX1_ARATH	L-ascorbate peroxidase 1, cytosolic	8422923	Genomic DNA structure of a gene encoding cytosolic ascorbate peroxidase from Arabidopsis thaliana.

O96028	NSD2_HUMAN	Probable histone-lysine N-methyltransferase NSD2	9618163	WHSC1, a 90 kb SET domain-containing gene, expressed in early development and homologous to a Drosophila dysmorphy gene maps in the Wolf-Hirschhorn syndrome critical region and is fused to IgH in t(4;14) multiple myeloma.

P38796	PPME1_YEAST	Protein phosphatase methylesterase 1	11060018	Carboxyl methylation of the phosphoprotein phosphatase 2A catalytic subunit promotes its functional association with regulatory subunits in vivo.

O70458	OSMR_MOUSE	Oncostatin-M-specific receptor subunit beta	9584176	Cloning and characterization of a specific receptor for mouse oncostatin M.

P12271	RLBP1_HUMAN	Retinaldehyde-binding protein 1	9326942	Mutation of the gene encoding cellular retinaldehyde-binding protein in autosomal recessive retinitis pigmentosa.

Q61125	BKRB1_MOUSE	B1 bradykinin receptor	8602848	Molecular cloning and functional characterization of a mouse bradykinin B1 receptor gene.

Q9XJ36	CLPR2_ARATH	ATP-dependent Clp protease proteolytic subunit-related protein 2, chloroplastic	16766689	Downregulation of ClpR2 leads to reduced accumulation of the ClpPRS protease complex and defects in chloroplast biogenesis in Arabidopsis.

Q9Z2Z8	DHCR7_RAT	7-dehydrocholesterol reductase	12031495	Structure and alternative splicing of the rat 7-dehydrocholesterol reductase gene.

Q9Z0X2	SL9A5_RAT	Sodium/hydrogen exchanger 5	9933642	Molecular cloning and functional expression of a rat Na+/H+ exchanger (NHE5) highly expressed in brain.

Q9Y5Y5	PEX16_HUMAN	Peroxisomal membrane protein PEX16	9837814	Mutation in PEX16 is causal in the peroxisome-deficient Zellweger syndrome of complementation group D.

P17897	LYZ1_MOUSE	Lysozyme C-1	14977423	Comparison of the microbicidal and muramidase activities of mouse lysozyme M and P.

Q09685	DRE4_SCHPO	DNA replication protein 4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O75665	OFD1_HUMAN	Oral-facial-digital syndrome 1 protein	19800048	OFD1 is mutated in X-linked Joubert syndrome and interacts with LCA5- encoded lebercilin.

Q9ERU2	ZNF22_RAT	Zinc finger protein 22	14706453	Molecular cloning, chromosomal mapping, and characteristic expression in tooth organ of rat and mouse Krox-25.

P46561	ATPB_CAEEL	ATP synthase subunit beta, mitochondrial	15563610	ATP-2 interacts with the PLAT domain of LOV-1 and is involved in Caenorhabditis elegans polycystin signaling.

Q62968	SCNAA_RAT	Sodium channel protein type 10 subunit alpha	8538791	A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons.

P32319	PEP1_YEAST	Vacuolar protein sorting/targeting protein PEP1	8187177	The sorting receptor for yeast vacuolar carboxypeptidase Y is encoded by the VPS10 gene.

P21507	SRMB_ECOLI	ATP-dependent RNA helicase srmB	2461520	An eIF-4A-like protein is a suppressor of an Escherichia coli mutant defective in 50S ribosomal subunit assembly.

Q12125	GET4_YEAST	Golgi to ER traffic protein 4	14562095	Global analysis of protein localization in budding yeast.

O13918	ZHF1_SCHPO	Zinc homeostasis factor 1	11886869	A transporter in the endoplasmic reticulum of Schizosaccharomyces pombe cells mediates zinc storage and differentially affects transition metal tolerance.

P14832	CYPH_YEAST	Peptidyl-prolyl cis-trans isomerase	10899127	Cyclophilin A and Ess1 interact with and regulate silencing by the Sin3-Rpd3 histone deacetylase.

P07527	WEE1_SCHPO	Mitosis inhibitor protein kinase wee1	3032459	Negative regulation of mitosis by wee1+, a gene encoding a protein kinase homolog.

P52333	JAK3_HUMAN	Tyrosine-protein kinase JAK3	8022790	Molecular cloning of L-JAK, a Janus family protein-tyrosine kinase expressed in natural killer cells and activated leukocytes.

Q9V3D5	DYRK2_DROME	Dual specificity tyrosine-phosphorylation-regulated kinase 2	12786602	dDYRK2: a novel dual-specificity tyrosine-phosphorylation-regulated kinase in Drosophila.

O14307	TRM61_SCHPO	tRNA (adenine-N(1)-)-methyltransferase catalytic subunit trm61	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P60763	RAC3_HUMAN	Ras-related C3 botulinum toxin substrate 3	9252344	Characterization of RAC3, a novel member of the Rho family.

Q8IDX6	RBP2A_PLAF7	Reticulocyte-binding protein 2 homolog a	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

P38781	RSC30_YEAST	Chromatin structure-remodeling complex protein RSC30	16204215	The RSC chromatin remodeling complex bears an essential fungal- specific protein module with broad functional roles.

P76641	GUAD_ECOLI	Guanine deaminase	10913105	Identification, expression, and characterization of Escherichia coli guanine deaminase.

Q9ULP0	NDRG4_HUMAN	Protein NDRG4	11352569	Characterization of the human NDRG gene family: a newly identified member, NDRG4, is specifically expressed in brain and heart.

O00270	GPR31_HUMAN	Probable G-protein coupled receptor 31	9205127	Isolation and chromosomal localization of GPR31, a human gene encoding a putative G protein-coupled receptor.

Q5RKZ7	MOCS1_MOUSE	Molybdenum cofactor biosynthesis protein 1	12471057	Molybdenum cofactor-deficient mice resemble the phenotype of human patients.

O14633	LCE2B_HUMAN	Late cornified envelope protein 2B	9344646	Positional cloning of novel skin-specific genes from the human epidermal differentiation complex.

O14016	UREF_SCHPO	Uncharacterized urease accessory protein ureF-like	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P32501	EI2BE_YEAST	Translation initiation factor eIF-2B subunit epsilon	8441423	Evidence that GCD6 and GCD7, translational regulators of GCN4, are subunits of the guanine nucleotide exchange factor for eIF-2 in Saccharomyces cerevisiae.

P58958	G39AC_DROME	Putative gustatory receptor 39a, isoform D	10710312	Candidate taste receptors in Drosophila.

P54708	AT12A_RAT	Potassium-transporting ATPase alpha chain 2	1320029	Isolation and characterization of a cDNA encoding the putative distal colon H+,K(+)-ATPase. Similarity of deduced amino acid sequence to gastric H+,K(+)-ATPase and Na+,K(+)-ATPase and mRNA expression in distal colon, kidney, and uterus.

P12962	CAF20_YEAST	Cap-associated protein CAF20	9144215	The p20 and Ded1 proteins have antagonistic roles in eIF4E-dependent translation in Saccharomyces cerevisiae.

P36009	DHR2_YEAST	Probable ATP-dependent RNA helicase DHR2	10982841	Dhr1p, a putative DEAH-Box RNA helicase, is associated with the box C+D snoRNP U3.

P00813	ADA_HUMAN	Adenosine deaminase	7599635	Four new adenosine deaminase mutations, altering a zinc-binding histidine, two conserved alanines, and a 5' splice site.

Q16799	RTN1_HUMAN	Reticulon-1	9560466	Neuronal differentiation is accompanied by NSP-C expression.

P05090	APOD_HUMAN	Apolipoprotein D	7918467	Structure of human apolipoprotein D: locations of the intermolecular and intramolecular disulfide links.

Q09825	SAD1_SCHPO	Spindle pole body-associated protein sad1	7744953	The product of the spindle formation gene sad1+ associates with the fission yeast spindle pole body and is essential for viability.

Q99N96	RM01_MOUSE	39S ribosomal protein L1, mitochondrial	11279069	Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria.

O96033	MOC2A_HUMAN	Molybdopterin synthase sulfur carrier subunit	15073332	Evidence for the physiological role of a rhodanese-like protein for the biosynthesis of the molybdenum cofactor in humans.

Q15629	TRAM1_HUMAN	Translocating chain-associated membrane protein 1	1315422	A protein of the endoplasmic reticulum involved early in polypeptide translocation.

P27812	KRBBA_MOUSE	Killer cell lectin-like receptor subfamily B member 1B allele A	10229828	Mouse NKR-P1B, a novel NK1.1 antigen with inhibitory function.

Q9NP31	SH22A_HUMAN	SH2 domain-containing protein 2A	9468509	Molecular cloning of a T cell-specific adapter protein (TSAd) containing an Src homology (SH) 2 domain and putative SH3 and phosphotyrosine binding sites.

P24492	DIP_DROME	Diptericin	2125051	Insect immunity. Characterization of a Drosophila cDNA encoding a novel member of the diptericin family of immune peptides.

P35359	OPSD_DANRE	Rhodopsin	10349978	ERRATUM
Q8IUN9	CLC10_HUMAN	C-type lectin domain family 10 member A	8598452	Molecular cloning and expression of cDNA encoding human macrophage c- type lectin: its unique carbohydrate binding specificity for Tn antigen.

Q99523	SORT_HUMAN	Sortilin	9756851	The 100-kDa neurotensin receptor is gp95/sortilin, a non-G-protein- coupled receptor.

P23025	XPA_HUMAN	DNA repair protein complementing XP-A cells	1601884	Mutational analysis of the structure and function of the Xeroderma pigmentosum group A complementing protein. Identification of essential domains for nuclear localization and DNA excision repair.

P30307	MPIP3_HUMAN	M-phase inducer phosphatase 3	11078813	An additional transcript of the cdc25C gene from A431 cells encodes a functional protein.

Q9R1X4	TIM_MOUSE	Protein timeless homolog	12875843	Tipin, a novel timeless-interacting protein, is developmentally co- expressed with timeless and disrupts its self-association.

Q8W1S1	DGDG2_ARATH	Digalactosyldiacylglycerol synthase 2, chloroplastic	14600212	Disruption of the two digalactosyldiacylglycerol synthase genes DGD1 and DGD2 in Arabidopsis reveals the existence of an additional enzyme of galactolipid synthesis.

Q58634	PSB_METJA	Proteasome subunit beta	19481527	Structural insights into the regulatory particle of the proteasome from Methanocaldococcus jannaschii.

P41916	RAN1_ARATH	GTP-binding nuclear protein Ran-1	9025305	Characterization of proteins that interact with the GTP-bound form of the regulatory GTPase Ran in Arabidopsis.

P43027	GDF5_MOUSE	Growth/differentiation factor 5	8145850	Limb alterations in brachypodism mice due to mutations in a new member of the TGF beta-superfamily.

P32166	MENA_ECOLI	1,4-dihydroxy-2-naphthoate octaprenyltransferase	9573170	Menaquinone (vitamin K2) biosynthesis: localization and characterization of the menA gene from Escherichia coli.

P61750	ARF4_MOUSE	ADP-ribosylation factor 4	8947846	Structure and intracellular localization of mouse ADP-ribosylation factors type 1 to type 6 (ARF1-ARF6).

Q9UT40	YIQ3_SCHPO	Uncharacterized protein C824.03c, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UTB0	YL88_SCHPO	Dilute domain-containing protein C25B8.08	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9ZVJ3	MA655_ARATH	65-kDa microtubule-associated protein 5	19060108	The C-terminal variable region specifies the dynamic properties of Arabidopsis microtubule-associated protein MAP65 isotypes.

Q9Y2W1	TR150_HUMAN	Thyroid hormone receptor-associated protein 3	10198638	Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators.

P01106	MYC_HUMAN	Myc proto-oncogene protein	15103331	Phosphorylation-dependent degradation of c-Myc is mediated by the F- box protein Fbw7.

Q9NQS7	INCE_HUMAN	Inner centromere protein	17956729	Structure of a Survivin-Borealin-INCENP core complex reveals how chromosomal passengers travel together.

O14683	P5I11_HUMAN	Tumor protein p53-inducible protein 11	9305847	A model for p53-induced apoptosis.

Q8AVJ9	FZD7B_XENLA	Frizzled-7-B	10446283	Two novel Xenopus frizzled genes expressed in developing heart and brain.

Q943E6	HS16B_ORYSJ	16.9 kDa class I heat shock protein 2	19135278	Expression analysis of nine rice heat shock protein genes under abiotic stresses and ABA treatment.

Q6PCN7	HLTF_MOUSE	Helicase-like transcription factor	9427542	Molecular cloning and characterization of P113, a mouse SNF2/SWI2- related transcription factor.

Q6DIC0	SMCA2_MOUSE	Probable global transcription activator SNF2L2	17640523	An essential switch in subunit composition of a chromatin remodeling complex during neural development.

O22160	TL15A_ARATH	Thylakoid lumenal 15 kDa protein 1, chloroplastic	11719511	Proteome map of the chloroplast lumen of Arabidopsis thaliana.

O88554	PARP2_MOUSE	Poly [ADP-ribose] polymerase 2	10364231	PARP-2, a novel mammalian DNA damage-dependent poly(ADP-ribose) polymerase.

P38871	SSP1_YEAST	Sporulation-specific protein 1	11742972	Prospore membrane formation linked to the leading edge protein (LEP) coat assembly.

O00623	PEX12_HUMAN	Peroxisome assembly protein 12	10562279	PEX12 interacts with PEX5 and PEX10 and acts downstream of receptor docking in peroxisomal matrix protein import.

O60294	LCMT2_HUMAN	Leucine carboxyl methyltransferase 2	12853982	p53RFP, a p53-inducible RING-finger protein, regulates the stability of p21WAF1.

P09038	FGF2_HUMAN	Heparin-binding growth factor 2	2435575	Cloning and expression of cDNA encoding human basic fibroblast growth factor.

Q8NCC3	PAG15_HUMAN	Group XV phospholipase A2	11790796	Cloning and characterization of a lysosomal phospholipase A2, 1-O- acylceramide synthase.

Q9NQY0	BIN3_HUMAN	Bridging integrator 3	11274158	Human BIN3 complements the F-actin localization defects caused by loss of Hob3p, the fission yeast homolog of Rvs161p.

Q9Y3I1	FBX7_HUMAN	F-box only protein 7	15145941	Fbx7 functions in the SCF complex regulating Cdk1-cyclin B- phosphorylated hepatoma up-regulated protein (HURP) proteolysis by a proline-rich region.

P59215	GNAO_RAT	Guanine nucleotide-binding protein G(o) subunit alpha	2820999	Molecular cloning of five GTP-binding protein cDNA species from rat olfactory neuroepithelium.

Q9ZQN8	CSLA7_ARATH	Probable mannan synthase 7	15647349	Expression of cellulose synthase-like (Csl) genes in insect cells reveals that CslA family members encode mannan synthases.

Q02650	PAX5_MOUSE	Paired box protein Pax-5	11799127	The interaction of Pax5 (BSAP) with Daxx can result in transcriptional activation in B cells.

Q9UJX4	APC5_HUMAN	Anaphase-promoting complex subunit 5	16364912	Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C.

Q39140	TGA6_ARATH	Transcription factor TGA6	9225852	DNA-binding properties, genomic organization and expression pattern of TGA6, a new member of the TGA family of bZIP transcription factors in Arabidopsis thaliana.

Q9P7J2	XLF1_SCHPO	Xrcc4-like factor 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q14330	GPR18_HUMAN	N-arachidonyl glycine receptor	16844083	Identification of N-arachidonylglycine as the endogenous ligand for orphan G-protein-coupled receptor GPR18.

O75962	TRIO_HUMAN	Triple functional domain protein	8643598	The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac- specific and rho-specific guanine nucleotide exchange factor domains.

P35606	COPB2_HUMAN	Coatomer subunit beta'	8335000	A 102 kDa subunit of a Golgi-associated particle has homology to beta subunits of trimeric G proteins.

Q8BGW0	THMS1_MOUSE	Protein THEMIS	19597499	Themis controls thymocyte selection through regulation of T cell antigen receptor-mediated signaling.

P35367	HRH1_HUMAN	Histamine H1 receptor	7925364	Stable expression of human H1-histamine-receptor cDNA in Chinese hamster ovary cells. Pharmacological characterisation of the protein, tissue distribution of messenger RNA and chromosomal localisation of the gene.

Q76I89	NDC80_CHICK	Kinetochore protein NDC80 homolog	15713649	The functional region of CENP-H interacts with the Nuf2 complex that localizes to centromere during mitosis.

Q8R4E9	CDT1_MOUSE	DNA replication factor Cdt1	14993212	Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding.

Q10134	FEP1_SCHPO	Iron-sensing transcription factor 1	14668334	The Schizosaccharomyces pombe corepressor Tup11 interacts with the iron-responsive transcription factor Fep1.

C7G3A0	MPPE1_CRIGR	Metallophosphoesterase 1	19837036	GPI glycan remodeling by PGAP5 regulates transport of GPI-anchored proteins from the ER to the Golgi.

Q9C5R8	BAS1B_ARATH	2-Cys peroxiredoxin BAS1-like, chloroplastic	12529539	Divergent light-, ascorbate-, and oxidative stress-dependent regulation of expression of the peroxiredoxin gene family in Arabidopsis.

O75462	CRLF1_HUMAN	Cytokine receptor-like factor 1	9686600	Cytokine-like factor-1, a novel soluble protein, shares homology with members of the cytokine type I receptor family.

O93235	CIRBA_XENLA	Cold-inducible RNA-binding protein A	10817911	Cloning and characterization of amphibian cold inducible RNA-binding protein.

Q06071	YL408_YEAST	Uncharacterized protein YLR408C	14562095	Global analysis of protein localization in budding yeast.

Q9JKJ9	CP39A_MOUSE	24-hydroxycholesterol 7-alpha-hydroxylase	10748047	Expression cloning of an oxysterol 7alpha-hydroxylase selective for 24-hydroxycholesterol.

Q5B7X2	MANA_EMENI	Mannan endo-1,4-beta-mannosidase A	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

Q96EY1	DNJA3_HUMAN	DnaJ homolog subfamily A member 3, mitochondrial	10411904	TID1, a human homolog of the Drosophila tumor suppressor l(2)tid, encodes two mitochondrial modulators of apoptosis with opposing functions.

Q62315	JARD2_MOUSE	Protein Jumonji	9376320	Organogenesis of the liver, thymus and spleen is affected in jumonji mutant mice.

P19367	HXK1_HUMAN	Hexokinase-1	3207429	Human hexokinase: sequences of amino- and carboxyl-terminal halves are homologous.

O18391	KRAK_DROME	Probable serine hydrolase	9831651	Identification and characterization of kraken, a gene encoding a putative hydrolytic enzyme in Drosophila melanogaster.

Q9Y5I3	PCDA1_HUMAN	Protocadherin alpha-1	10380929	A striking organization of a large family of human neural cadherin- like cell adhesion genes.

P49450	CENPA_HUMAN	Histone H3-like centromeric protein A	19410544	Centromere-specific assembly of CENP-A nucleosomes is mediated by HJURP.

Q9P6L6	DPOZ_SCHPO	DNA polymerase zeta catalytic subunit	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Z1Z6	ILKAP_RAT	Integrin-linked kinase-associated serine/threonine phosphatase 2C	9857069	Cloning and characterization of a novel mammalian PP2C isozyme.

Q9XSD4	PTAFR_PIG	Platelet-activating factor receptor	11916258	Comparison of the coding sequence of the platelet-activating factor receptor gene in three species.

Q9Y7Q9	YCX2_SCHPO	Probable metabolite transporter C2H8.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q09142	ORC2_SCHPO	Origin recognition complex subunit 2	10535928	Identification and reconstitution of the origin recognition complex from Schizosaccharomyces pombe.

Q792Q4	CRIPT_RAT	Cysteine-rich PDZ-binding protein	9581762	CRIPT, a novel postsynaptic protein that binds to the third PDZ domain of PSD-95/SAP90.

O24646	HY5_ARATH	Transcription factor HY5	12023303	Two interacting bZIP proteins are direct targets of COP1-mediated control of light-dependent gene expression in Arabidopsis.

O94417	CWC26_SCHPO	Pre-mRNA-splicing factor cwc26	11884590	Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

P30937	SSR4_RAT	Somatostatin receptor type 4	8175684	Functional coupling of SSTR4, a major hippocampal somatostatin receptor, to adenylate cyclase inhibition, arachidonate release and activation of the mitogen-activated protein kinase cascade.

Q5U5M8	BL1S3_MOUSE	Biogenesis of lysosome-related organelles complex 1 subunit 3	15265785	Reduced pigmentation (rp), a mouse model of Hermansky-Pudlak syndrome, encodes a novel component of the BLOC-1 complex.

Q06541	ARV1_YEAST	Protein ARV1	12145310	Yeast cells lacking the ARV1 gene harbor defects in sphingolipid metabolism. Complementation by human ARV1.

Q9Z301	PER2_RAT	Period circadian protein homolog 2	9765215	Multitissue circadian expression of rat period homologue (rPer2) mRNA is governed by the mammalian circadian clock, the suprachiasmatic nucleus in the brain.

P48182	ACR2_CAEEL	Acetylcholine receptor subunit beta-type acr-2	8581398	Molecular cloning and functional co-expression of a Caenorhabditis elegans nicotinic acetylcholine receptor subunit (acr-2).

Q92597	NDRG1_HUMAN	Protein NDRG1	9605764	Cap43, a novel gene specifically induced by Ni2+ compounds.

Q96524	CRY2_ARATH	Cryptochrome-2	16093319	A role for Arabidopsis cryptochromes and COP1 in the regulation of stomatal opening.

P04652	TSHB_RAT	Thyrotropin subunit beta	3027091	Isolation and characterization of the rat thyrotropin beta-subunit gene. Differential regulation of two transcriptional start sites by thyroid hormone.

O57604	PODXL_CHICK	Podocalyxin	17311105	The CD34-related molecule podocalyxin is a potent inducer of microvillus formation.

P55884	EIF3B_HUMAN	Eukaryotic translation initiation factor 3 subunit B	17322308	Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry.

P70181	PI51B_MOUSE	Phosphatidylinositol-4-phosphate 5-kinase type-1 beta	8798574	Cloning of cDNAs encoding two isoforms of 68-kDa type I phosphatidylinositol 4-phosphate 5-kinase.

P29384	SEP2_ARATH	Developmental protein SEPALLATA 2	9418042	Specific interactions between the K domains of AG and AGLs, members of the MADS domain family of DNA binding proteins.

P05933	CALM_SCHPO	Calmodulin	9635188	Rng2p, a protein required for cytokinesis in fission yeast, is a component of the actomyosin ring and the spindle pole body.

P52631	STAT3_RAT	Signal transducer and activator of transcription 3	8530402	Transcription factors Stat3 and Stat5b are present in rat liver nuclei late in an acute phase response and bind interleukin-6 response elements.

Q9U9Y8	NLK_CAEEL	Serine/threonine kinase NLK	10391246	MAP kinase and Wnt pathways converge to downregulate an HMG-domain repressor in Caenorhabditis elegans.

Q04739	GAL83_YEAST	SNF1 protein kinase subunit beta-3	11331606	Subcellular localization of the Snf1 kinase is regulated by specific beta subunits and a novel glucose signaling mechanism.

Q8IWB7	WDFY1_HUMAN	WD repeat and FYVE domain-containing protein 1	11739631	FENS-1 and DFCP1 are FYVE domain-containing proteins with distinct functions in the endosomal and Golgi compartments.

P53051	MALX3_YEAST	Oligo-1,6-glucosidase	15291818	Val216 decides the substrate specificity of alpha-glucosidase in Saccharomyces cerevisiae.

Q96KP1	EXOC2_HUMAN	Exocyst complex component 2	12459492	DelGEF, a homologue of the Ran guanine nucleotide exchange factor RanGEF, binds to the exocyst component Sec5 and modulates secretion.

Q54QR3	RB32A_DICDI	Ras-related protein Rab-32A	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P37837	TALDO_HUMAN	Transaldolase	9524206	Cloning and chromosomal localization of a paralog and a mouse homolog of the human transaldolase gene.

B5LUQ7	FALX3_LITFA	Preprofallaxidin-3	18803332	The fallaxidin peptides from the skin secretion of the eastern dwarf tree frog Litoria fallax. Sequence determination by positive and negative ion electrospray mass spectrometry: antimicrobial activity and cDNA cloning of the fallaxidins.

Q02196	KAPS_YEAST	Adenylyl-sulfate kinase	1654509	Cloning, nucleotide sequence, and regulation of MET14, the gene encoding the APS kinase of Saccharomyces cerevisiae.

O94722	CTR4_SCHPO	Copper transport protein ctr4	11274192	Identification of a novel high affinity copper transport complex in the fission yeast Schizosaccharomyces pombe.

Q92805	GOGA1_HUMAN	Golgin subfamily A member 1	9324025	Molecular cloning of a novel 97-kd Golgi complex autoantigen associated with Sjoegren's syndrome.

O04500	COBL6_ARATH	COBRA-like protein 6	12376623	The COBRA family of putative GPI-anchored proteins in Arabidopsis. A new fellowship in expansion.

Q9ESD7	DYSF_MOUSE	Dysferlin	12736685	Defective membrane repair in dysferlin-deficient muscular dystrophy.

Q6RG02	VIT_FENME	Vitellogenin	16289995	Characterization of vitellin from the ovaries of the banana shrimp Litopenaeus merguiensis.

O75943	RAD17_HUMAN	Cell cycle checkpoint protein RAD17	15538388	Interaction between human MCM7 and Rad17 proteins is required for replication checkpoint signaling.

Q8LE52	DHAR3_ARATH	Glutathione S-transferase DHAR3, chloroplastic	15028209	The Arabidopsis thaliana chloroplast proteome reveals pathway abundance and novel protein functions.

P58463	FOXP2_MOUSE	Forkhead box protein P2	14701752	Transcriptional and DNA binding activity of the Foxp1/2/4 family is modulated by heterotypic and homotypic protein interactions.

P87377	VEGTA_XENLA	T-box protein VegT-A	9165117	A vegetally localized T-box transcription factor in Xenopus eggs specifies mesoderm and endoderm and is essential for embryonic mesoderm formation.

Q8WQG9	JNK1_CAEEL	Stress-activated protein kinase jnk-1	11738026	UNC-16, a JNK-signaling scaffold protein, regulates vesicle transport in C. elegans.

P08539	GPA1_YEAST	Guanine nucleotide-binding protein alpha-1 subunit	2107073	Regulation of the yeast pheromone response pathway by G protein subunits.

P23845	CYSN_ECOLI	Sulfate adenylyltransferase subunit 1	2828368	The sulfate activation locus of Escherichia coli K12: cloning, genetic, and enzymatic characterization.

Q80UE6	WNK4_MOUSE	Serine/threonine-protein kinase WNK4	14608358	WNK4 regulates the balance between renal NaCl reabsorption and K+ secretion.

P00520	ABL1_MOUSE	Tyrosine-protein kinase ABL1	9636171	Nuclear-cytoplasmic shuttling of C-ABL tyrosine kinase.

P11465	PSG2_HUMAN	Pregnancy-specific beta-1-glycoprotein 2	3260773	The human pregnancy-specific beta 1-glycoprotein (PS beta G) and the carcinoembryonic antigen (CEA)-related proteins are members of the same multigene family.

P69851	DAD4_YEAST	DASH complex subunit DAD4	15632076	Genetic analysis of the kinetochore DASH complex reveals an antagonistic relationship with the ras/protein kinase A pathway and a novel subunit required for Ask1 association.

Q9NVS2	RT18A_HUMAN	28S ribosomal protein S18a, mitochondrial	11279123	The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present.

O35427	RPC9_MOUSE	DNA-directed RNA polymerase III subunit RPC9	9322931	Inhibitory effect of calcitonin gene-related peptide on myometrial contractility is diminished at parturition.

Q9FJ17	DI197_ARATH	Protein DEHYDRATION-INDUCED 19 homolog 7	15705950	HYPERSENSITIVE TO RED AND BLUE 1, a ZZ-type zinc finger protein, regulates phytochrome B-mediated red and cryptochrome-mediated blue light responses.

P48551	INAR2_HUMAN	Interferon alpha/beta receptor 2	7588638	Mutant U5A cells are complemented by an interferon-alpha beta receptor subunit generated by alternative processing of a new member of a cytokine receptor gene cluster.

Q9FL28	FLS2_ARATH	LRR receptor-like serine/threonine-protein kinase FLS2	17626179	The receptor-like kinase SERK3/BAK1 is a central regulator of innate immunity in plants.

O00192	ARVC_HUMAN	Armadillo repeat protein deleted in velo-cardio-facial syndrome	9126485	Identification of a new human catenin gene family member (ARVCF) from the region deleted in velo-cardio-facial syndrome.

Q9NIV0	RHGA_DICDI	Rhesus-like glycoprotein A	11220631	Localization of the Rh50-like protein to the contractile vacuole in Dictyostelium.

Q04418	RBA50_YEAST	RNA polymerase II-associated protein RBA50	14562095	Global analysis of protein localization in budding yeast.

P08417	FUMH_YEAST	Fumarate hydratase, mitochondrial	11502169	Yeast mitochondrial dehydrogenases are associated in a supramolecular complex.

Q9HB90	RRAGC_HUMAN	Ras-related GTP-binding protein C	14660641	A novel human nucleolar protein, Nop132, binds to the G proteins, RRAG A/C/D.

Q9USL4	NUP61_SCHPO	Nucleoporin nup61	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NP98	MYOZ1_HUMAN	Myozenin-1	10984498	FATZ, a filamin-, actinin-, and telethonin-binding protein of the Z- disc of skeletal muscle.

Q99P75	RAB9A_RAT	Ras-related protein Rab-9A	12051767	Intracellular membrane trafficking pathways in bone-resorbing osteoclasts revealed by cloning and subcellular localization studies of small GTP-binding rab proteins.

P56705	WNT4_HUMAN	Protein Wnt-4	15317892	A WNT4 mutation associated with Muellerian-duct regression and virilization in a 46,XX woman.

Q66K89	E4F1_HUMAN	Transcription factor E4F1	9121437	The adenovirus E1A-regulated transcription factor E4F is generated from the human homolog of nuclear factor phiAP3.

P20908	CO5A1_HUMAN	Collagen alpha-1(V) chain	9099729	The membrane-spanning proteoglycan NG2 binds to collagens V and VI through the central nonglobular domain of its core protein.

Q92376	KLP1_SCHPO	Kinesin-like protein 1	11694582	pkl1(+)and klp2(+): two kinesins of the Kar3 subfamily in fission yeast perform different functions in both mitosis and meiosis.

P25294	SIS1_YEAST	Protein SIS1	8513501	The yeast SIS1 protein, a DnaJ homolog, is required for the initiation of translation.

Q869S9	CBPE_DICDI	Calcium-binding protein E	14706075	Identification and characterization of novel calcium-binding proteins of Dictyostelium and their spatial expression patterns during development.

Q9SL05	PGR5_ARATH	Protein PROTON GRADIENT REGULATION 5, chloroplastic	18243102	A complex containing PGRL1 and PGR5 is involved in the switch between linear and cyclic electron flow in Arabidopsis.

P16860	ANFB_HUMAN	Natriuretic peptides B	1672777	Selective activation of the B natriuretic peptide receptor by C-type natriuretic peptide (CNP).

Q9FYK5	ESR2_ARATH	Ethylene-responsive transcription factor ESR2	17056621	The ENHANCER OF SHOOT REGENERATION 2 gene in Arabidopsis regulates CUP-SHAPED COTYLEDON 1 at the transcriptional level and controls cotyledon development.

P49687	NU145_YEAST	Nucleoporin NUP145	11823431	Modular self-assembly of a Y-shaped multiprotein complex from seven nucleoporins.

P85498	ITRA_ALBKA	Kunitz-type trypsin inhibitor alpha chain	18368297	Identification of a Kunitz inhibitor from Albizzia kalkora and its inhibitory effect against pest midgut proteases.

Q9SIB9	ACO2M_ARATH	Aconitate hydratase 2, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q9H2X0	CHRD_HUMAN	Chordin	11472837	The human chordin gene encodes several differentially expressed spliced variants with distinct BMP opposing activities.

P86169	PA2A_CRODR	Phospholipase A2 isozyme A	19013478	Enzymatic and structural characterization of new PLA2 isoform isolated from white venom of Crotalus durissus ruruima.

P40017	YAT2_YEAST	Carnitine O-acetyltransferase YAT2	18427809	Carnitine and carnitine acetyltransferases in the yeast Saccharomyces cerevisiae: a role for carnitine in stress protection.

P40901	ISP5_SCHPO	Sexual differentiation process putative amino-acid permease isp5	7954893	Identification and characterization of genes induced during sexual differentiation in Schizosaccharomyces pombe.

P93829	PRA1D_ARATH	PRA1 family protein D	18583532	The PRA1 gene family in Arabidopsis.

Q00402	NUM1_YEAST	Nuclear migration protein NUM1	11121446	The cortical protein Num1p is essential for dynein-dependent interactions of microtubules with the cortex.

Q12084	YD020_YEAST	Putative uridine kinase YDR020C	14562095	Global analysis of protein localization in budding yeast.

Q8JHV9	BIR7A_XENLA	Baculoviral IAP repeat-containing protein 7-A	17008917	XLX is an IAP family member regulated by phosphorylation during meiosis.

O61735	CLOCK_DROME	Circadian locomoter output cycles protein kaput	9616122	Closing the circadian loop: CLOCK-induced transcription of its own inhibitors per and tim.

P53935	NST1_YEAST	Stress response protein NST1	11816027	Involvement of Nst1p/YNL091w and Msl1p, a U2B'' splicing factor, in Saccharomyces cerevisiae salt tolerance.

P38967	TAT2_YEAST	Tryptophan permease	7523855	Two FK506 resistance-conferring genes in Saccharomyces cerevisiae, TAT1 and TAT2, encode amino acid permeases mediating tyrosine and tryptophan uptake.

Q9UQV4	LAMP3_HUMAN	Lysosome-associated membrane glycoprotein 3	9721848	Isolation and characterization of a novel human lung-specific gene homologous to lysosomal membrane glycoprotein 1 and 2; significantly increased expression in cancers of various tissues.

P16045	LEG1_MOUSE	Galectin-1	3020551	Evidence that a human soluble beta-galactoside-binding lectin is encoded by a family of genes.

P45452	MMP13_HUMAN	Collagenase 3	8207000	Molecular cloning and expression of collagenase-3, a novel human matrix metalloproteinase produced by breast carcinomas.

A7LFZ6	DCL4_ORYSJ	Endoribonuclease Dicer homolog 4	17905898	Oryza sativa dicer-like4 reveals a key role for small interfering RNA silencing in plant development.

Q10740	LKHA4_YEAST	Leukotriene A-4 hydrolase	10574934	Cloning and characterization of a bifunctional leukotriene A(4) hydrolase from Saccharomyces cerevisiae.

Q9EPK8	TRPV4_MOUSE	Transient receptor potential cation channel subfamily V member 4	14517216	Microtubule-associated protein 7 increases the membrane expression of transient receptor potential vanilloid 4 (TRPV4).

Q5T750	XP32_HUMAN	Skin-specific protein 32	9344646	Positional cloning of novel skin-specific genes from the human epidermal differentiation complex.

Q8BGC4	ZADH2_MOUSE	Zinc-binding alcohol dehydrogenase domain-containing protein 2	19091015	Predicted mouse peroxisome-targeted proteins and their actual subcellular locations.

Q6NZ07	NCLN_DANRE	Nicalin-1	15257293	Nicalin and its binding partner Nomo are novel Nodal signaling antagonists.

Q9SL15	GRP3_ARATH	Glycine-rich protein 3	11335717	Interaction of the Arabidopsis receptor protein kinase Wak1 with a glycine-rich protein, AtGRP-3.

P47150	RT07_YEAST	37S ribosomal protein S7, mitochondrial	11278769	Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues.

Q70EK8	UBP53_HUMAN	Inactive ubiquitin carboxyl-terminal hydrolase 53	14715245	Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases.

Q22712	MTMR3_CAEEL	Myotublarin-related protein 3	18393358	Characterization and functional studies of a FYVE domain-containing phosphatase in C. elegans.

P38853	KEL1_YEAST	Kelch repeat-containing protein 1	9786949	Identification of Kel1p, a kelch domain-containing protein involved in cell fusion and morphology in Saccharomyces cerevisiae.

P24870	CG23_YEAST	G2/mitotic-specific cyclin-3	1427070	Cyclin-B homologs in Saccharomyces cerevisiae function in S phase and in G2.

O15392	BIRC5_HUMAN	Baculoviral IAP repeat-containing protein 5	10626797	Survivin-deltaEx3 and survivin-2B: two novel splice variants of the apoptosis inhibitor survivin with different antiapoptotic properties.

Q9UIU6	SIX4_HUMAN	Homeobox protein SIX4	10640827	Structure and chromosome mapping of the human SIX4 and murine Six4 genes.

P0AF98	LPTF_ECOLI	Lipopolysaccharide export system permease protein lptF	18375759	Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.

P51587	BRCA2_HUMAN	Breast cancer type 2 susceptibility protein	15314155	BRCA2 is ubiquitinated in vivo and interacts with USP11, a deubiquitinating enzyme that exhibits prosurvival function in the cellular response to DNA damage.

Q9P7C9	DCPS_SCHPO	Scavenger mRNA-decapping enzyme DcpS	12366830	A nuclear protein in Schizosaccharomyces pombe with homology to the human tumour suppressor Fhit has decapping activity.

Q9JI11	STK4_MOUSE	Serine/threonine-protein kinase 4	20080689	Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver.

Q9UKV8	AGO2_HUMAN	Protein argonaute-2	10534406	Human eukaryotic initiation factor EIF2C1 gene: cDNA sequence, genomic organization, localization to chromosomal bands 1p34-p35, and expression.

Q75W84	ANR_EISFO	Annetocin receptor	15175002	Identification of a novel receptor for an invertebrate oxytocin/vasopressin superfamily peptide: molecular and functional evolution of the oxytocin/vasopressin superfamily.

O88202	LPP60_RAT	60 kDa lysophospholipase	8119970	Purification, characterization, and inhibition by phosphatidic acid of lysophospholipase transacylase from rat liver.

Q9UTH0	NU132_SCHPO	Nucleoporin nup132	15116432	Identification of genes encoding putative nucleoporins and transport factors in the fission yeast Schizosaccharomyces pombe: a deletion analysis.

P87245	KMS1_SCHPO	Karyogamy meiotic segregation protein 1	14655046	Two-hybrid search for proteins that interact with Sad1 and Kms1, two membrane-bound components of the spindle pole body in fission yeast.

Q9QY31	SNAI3_MOUSE	Zinc finger protein SNAI3	10606664	A novel snail-related transcription factor Smuc regulates basic helix-loop-helix transcription factor activities via specific E-box motifs.

P27814	KLRBC_MOUSE	Killer cell lectin-like receptor subfamily B member 1C	10229823	The NKR-P1B gene product is an inhibitory receptor on SJL/J NK cells.

P36027	MID2_YEAST	Cell wall integrity sensor MID2	12949174	A synthetic analysis of the Saccharomyces cerevisiae stress sensor Mid2p, and identification of a Mid2p-interacting protein, Zeo1p, that modulates the PKC1-MPK1 cell integrity pathway.

O04291	ATB14_ARATH	Homeobox-leucine zipper protein ATHB-14	15598805	Class III homeodomain-leucine zipper gene family members have overlapping, antagonistic, and distinct roles in Arabidopsis development.

O49686	PYR1_ARATH	Abscisic acid receptor PYR1	19933100	Structural mechanism of abscisic acid binding and signaling by dimeric PYR1.

P62857	RS28_HUMAN	40S ribosomal protein S28	8706699	Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry.

Q9BT67	NFIP1_HUMAN	NEDD4 family-interacting protein 1	12761501	Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.

O60229	KALRN_HUMAN	Kalirin	9285789	Huntingtin-associated protein 1 (HAP1) binds to a Trio-like polypeptide, with a rac1 guanine nucleotide exchange factor domain.

P06316	LV107_HUMAN	Ig lambda chain V-I region BL2	6095199	Molecular cloning of a human immunoglobulin lambda chain variable sequence.

Q9M0S5	ISOA3_ARATH	Isoamylase 3, chloroplastic	18815382	Further evidence for the mandatory nature of polysaccharide debranching for the aggregation of semicrystalline starch and for overlapping functions of debranching enzymes in Arabidopsis leaves.

Q16873	LTC4S_HUMAN	Leukotriene C4 synthase	8052639	Expression cloning of a cDNA for human leukotriene C4 synthase, an integral membrane protein conjugating reduced glutathione to leukotriene A4.

P14882	PCCA_RAT	Propionyl-CoA carboxylase alpha chain, mitochondrial	2745462	Sequence analysis, biogenesis, and mitochondrial import of the alpha- subunit of rat liver propionyl-CoA carboxylase.

P60228	EIF3E_HUMAN	Eukaryotic translation initiation factor 3 subunit E	10504338	Interaction between the Ret finger protein and the Int-6 gene product and co-localisation into nuclear bodies.

P36122	BCH2_YEAST	Protein BCH2	17000877	Exomer: a coat complex for transport of select membrane proteins from the trans-Golgi network to the plasma membrane in yeast.

Q06132	SGD1_YEAST	Suppressor of glycerol defect protein 1	12073033	Phospholipase C interacts with Sgd1p and is required for expression of GPD1 and osmoresistance in Saccharomyces cerevisiae.

P02833	ANTP_DROME	Homeotic protein antennapedia	7903398	Determination of the nuclear magnetic resonance solution structure of an Antennapedia homeodomain-DNA complex.

Q03433	VPS71_YEAST	Vacuolar protein sorting-associated protein 71	12134085	Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae.

Q9NPD3	EXOS4_HUMAN	Exosome complex exonuclease RRP41	11110791	Three novel components of the human exosome.

Q07970	ATK1_ARATH	Kinesin-1	11973272	The Arabidopsis ATK1 gene is required for spindle morphogenesis in male meiosis.

O82794	AGL24_ARATH	MADS-box protein AGL24	18339670	Direct interaction of AGL24 and SOC1 integrates flowering signals in Arabidopsis.

Q91ZM9	DOK5_MOUSE	Docking protein 5	11470823	Novel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation.

Q62209	SYCP1_MOUSE	Synaptonemal complex protein 1	15944401	Two novel proteins recruited by synaptonemal complex protein 1 (SYCP1) are at the center of meiosis.

Q60715	P4HA1_MOUSE	Prolyl 4-hydroxylase subunit alpha-1	7753822	Cloning, baculovirus expression, and characterization of a second mouse prolyl 4-hydroxylase alpha-subunit isoform: formation of an alpha 2 beta 2 tetramer with the protein disulfide-isomerase/beta subunit.

P84279	PA2B_RANPA	Palustrin-2b	11087945	Multiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris.

Q9UTQ9	SPC2_SCHPO	Signal peptidase complex subunit spc2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O13788	SSR1_SCHPO	SWI/SNF and RSC complexes subunit ssr1	18622392	Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast.

Q03697	YMD8_YEAST	Putative nucleotide-sugar transporter YMD8	14562095	Global analysis of protein localization in budding yeast.

Q94A97	UBC35_ARATH	Ubiquitin-conjugating enzyme E2 35	18178771	Arabidopsis UEV1D promotes lysine-63-linked polyubiquitination and is involved in DNA damage response.

P28571	SC6A9_MOUSE	Sodium- and chloride-dependent glycine transporter 1	1618338	Cloning and expression of a glycine transporter from mouse brain.

Q9UTE6	MAK16_SCHPO	Protein mak16	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q86JA1	PRS7_DICDI	26S protease regulatory subunit 7	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q08162	RRP44_YEAST	Exosome complex exonuclease DIS3	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q91035	SHH_CHICK	Sonic hedgehog protein	8269518	Sonic hedgehog mediates the polarizing activity of the ZPA.

P37173	TGFR2_HUMAN	TGF-beta receptor type-2	11483955	TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation.

Q9VHN9	HPS5_DROME	Hermansky-Pudlak syndrome 5 protein homolog	17156100	The Drosophila pigmentation gene pink (p) encodes a homologue of human Hermansky-Pudlak syndrome 5 (HPS5).

Q06489	MTNA_YEAST	Methylthioribose-1-phosphate isomerase	15215245	Crystal structure of yeast Ypr118w, a methylthioribose-1-phosphate isomerase related to regulatory eIF2B subunits.

Q811D0	DLG1_MOUSE	Disks large homolog 1	11238884	Craniofacial dysmorphogenesis including cleft palate in mice with an insertional mutation in the discs large gene.

P39692	MET10_YEAST	Sulfite reductase [NADPH] flavoprotein component	7928966	Two divergent MET10 genes, one from Saccharomyces cerevisiae and one from Saccharomyces carlsbergensis, encode the alpha subunit of sulfite reductase and specify potential binding sites for FAD and NADPH.

Q01855	RS15_YEAST	40S ribosomal protein S15	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

P83616	GRP78_ASPNG	78 kDa glucose-regulated protein homolog	9370263	The ER chaperone encoding bipA gene of black Aspergilli is induced by heat shock and unfolded proteins.

P60602	ROMO1_HUMAN	Reactive oxygen species modulator 1	16842742	A novel protein, Romo1, induces ROS production in the mitochondria.

P25045	LCB1_YEAST	Serine palmitoyltransferase 1	10713067	Tsc3p is an 80-amino acid protein associated with serine palmitoyltransferase and required for optimal enzyme activity.

Q05066	SRY_HUMAN	Sex-determining region Y protein	1695712	A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif.

P42284	LOLA2_DROME	Longitudinals lacking protein, isoforms H/M/V	11880341	Lola regulates midline crossing of CNS axons in Drosophila.

Q9UEW3	MARCO_HUMAN	Macrophage receptor MARCO	10331948	Structure and chromosomal localization of the human and murine genes for the macrophage MARCO receptor.

Q9P7T0	SIB2_SCHPO	L-ornithine 5-monooxygenase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P97390	VPS45_MOUSE	Vacuolar protein sorting-associated protein 45	9045632	Identification of a mammalian Golgi Sec1p-like protein, mVps45.

P40069	IMB4_YEAST	Importin subunit beta-4	9321403	Yrb4p, a yeast ran-GTP-binding protein involved in import of ribosomal protein L25 into the nucleus.

P32784	GPT1_YEAST	Glycerol-3-phosphate O-acyltransferase 1	11544256	The initial step of the glycerolipid pathway: identification of glycerol-3-phosphate / dihydroxyacetone phosphate dual substrate acyltransferases in Saccharomyces cerevisiae.

Q9PVE4	THB_DANRE	Thyroid hormone receptor beta	18248177	Cloning, genomic organization, and expression analysis of zebrafish nuclear receptor coactivator, TIF2.

P43007	SATT_HUMAN	Neutral amino acid transporter A	8101838	Cloning and expression of a human neutral amino acid transporter with structural similarity to the glutamate transporter gene family.

Q14863	PO6F1_HUMAN	POU domain, class 6, transcription factor 1	7908264	A human POU domain gene, mPOU, is expressed in developing brain and specific adult tissues.

Q54EW0	FRMA_DICDI	FERM domain-containing protein A	19002378	Loss of FrmA leads to increased cell-cell adhesion and impaired multi-cellular development of Dictyostelium cells.

Q9C0Z3	SLX9_SCHPO	Ribosome biogenesis protein slx9	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8K3M5	CABL2_MOUSE	CDK5 and ABL1 enzyme substrate 2	11955625	Ik3-2, a relative to ik3-1/cables, is associated with cdk3, cdk5, and c-abl.

O57437	DAZLA_XENLA	Deleted in azoospermia-like-A	16001084	The DAZL family proteins are PABP-binding proteins that regulate translation in germ cells.

Q99K23	UFSP2_MOUSE	Ufm1-specific protease 2	17182609	Two novel ubiquitin-fold modifier 1 (Ufm1)-specific Proteases, UfSP1 and UfSP2.

P56282	DPOE2_HUMAN	DNA polymerase epsilon subunit 2	9405441	Purification, cDNA cloning, and gene mapping of the small subunit of human DNA polymerase epsilon.

Q61074	PPM1G_MOUSE	Protein phosphatase 1G	9271424	FIN13, a novel growth factor-inducible serine-threonine phosphatase which can inhibit cell cycle progression.

Q9P778	DPP5_SCHPO	Dipeptidyl-peptidase 5	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UHB7	AFF4_HUMAN	AF4/FMR2 family member 4	10588740	AF5q31, a newly identified AF4-related gene, is fused to MLL in infant acute lymphoblastic leukemia with ins(5;11)(q31;q13q23).

Q15650	TRIP4_HUMAN	Activating signal cointegrator 1	10454579	Activating signal cointegrator 1, a novel transcription coactivator of nuclear receptors, and its cytosolic localization under conditions of serum deprivation.

O35796	C1QBP_RAT	Complement component 1 Q subcomponent-binding protein, mitochondrial	9414106	Characterisation of the rat and mouse homologues of gC1qBP, a 33 kDa glycoprotein that binds to the globular 'heads' of C1q.

P07278	KAPR_YEAST	cAMP-dependent protein kinase regulatory subunit	3037314	Cloning and characterization of BCY1, a locus encoding a regulatory subunit of the cyclic AMP-dependent protein kinase in Saccharomyces cerevisiae.

Q8WXX0	DYH7_HUMAN	Dynein heavy chain 7, axonemal	11877439	Identification of dynein heavy chain 7 as an inner arm component of human cilia that is synthesized but not assembled in a case of primary ciliary dyskinesia.

Q9GZX3	CHST6_HUMAN	Carbohydrate sulfotransferase 6	11352640	Sulfation of endothelial mucin by corneal keratan N-acetylglucosamine 6-O-sulfotransferase (GST-4beta).

Q6R6M4	U17L2_HUMAN	Ubiquitin carboxyl-terminal hydrolase 17-like protein 2	20228808	Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A.

Q9UKP4	ATS7_HUMAN	A disintegrin and metalloproteinase with thrombospondin motifs 7	10464288	ADAM-TS5, ADAM-TS6, and ADAM-TS7, novel members of a new family of zinc metalloproteases.

Q12933	TRAF2_HUMAN	TNF receptor-associated factor 2	10809768	TAJ, a novel member of the tumor necrosis factor receptor family, activates the c-Jun N-terminal kinase pathway and mediates caspase- independent cell death.

Q8L840	RQL4A_ARATH	ATP-dependent DNA helicase Q-like 4A	12856935	Arabidopsis RecQsim, a plant-specific member of the RecQ helicase family, can suppress the MMS hypersensitivity of the yeast sgs1 mutant.

P08779	K1C16_HUMAN	Keratin, type I cytoskeletal 16	7539673	Keratin 16 and keratin 17 mutations cause pachyonychia congenita.

Q9Z0E8	S22A5_MOUSE	Solute carrier family 22 member 5	11010964	Molecular and functional characterization of organic cation/carnitine transporter family in mice.

Q9WVC1	SLIT2_RAT	Slit homolog 2 protein	11754167	Spatiotemporal expression patterns of slit and robo genes in the rat brain.

P22807	SLOU_DROME	Homeobox protein slou	1980118	A new Drosophila homeo box gene is expressed in mesodermal precursor cells of distinct muscles during embryogenesis.

P92973	CCA1_ARATH	Protein CCA1	11486091	Reciprocal regulation between TOC1 and LHY/CCA1 within the Arabidopsis circadian clock.

Q24459	PCL_DROME	Polycomb protein Pcl	7956837	Molecular characterisation of the Polycomblike gene of Drosophila melanogaster, a trans-acting negative regulator of homeotic gene expression.

Q62315	JARD2_MOUSE	Protein Jumonji	20064376	Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells.

Q8BU91	S26A9_MOUSE	Solute carrier family 26 member 9	15800055	SLC26A9 is expressed in gastric surface epithelial cells, mediates Cl-/HCO3- exchange, and is inhibited by NH4+.

Q9YGW7	DAZL_DANRE	Deleted in azoospermia-like	12296827	Zebrafish DAZ-like protein controls translation via the sequence 'GUUC'.

Q3U5Q7	CMPK2_MOUSE	UMP-CMP kinase 2, mitochondrial	7751651	A unique member of the thymidylate kinase family that is induced during macrophage activation.

Q9H5Q4	TFB2M_HUMAN	Dimethyladenosine transferase 2, mitochondrial	12897151	Human mitochondrial transcription factor B1 interacts with the C- terminal activation region of h-mtTFA and stimulates transcription independently of its RNA methyltransferase activity.

P40847	SAP1_SCHPO	Switch-activating protein 1	14555473	Fission yeast Sap1 protein is essential for chromosome stability.

P19157	GSTP1_MOUSE	Glutathione S-transferase P 1	7982937	Two murine GSTpi genes are arranged in tandem and are differentially expressed.

P23582	ANFC_HUMAN	C-type natriuretic peptide	1672777	Selective activation of the B natriuretic peptide receptor by C-type natriuretic peptide (CNP).

Q04759	KPCT_HUMAN	Protein kinase C theta type	7686153	Molecular cloning and expression of a cDNA encoding a novel isoenzyme of protein kinase C (nPKC). A new member of the nPKC family expressed in skeletal muscle, megakaryoblastic cells, and platelets.

P84823	BRK12_ASCTR	Bradykinin-like peptide AV-12	15922344	Bradykinin-related peptides and tryptophyllins in the skin secretions of the most primitive extant frog, Ascaphus truei.

Q5W8I8	VGL2A_DANRE	Vesicular glutamate transporter 2.1	17196531	Vesicular glutamate transport at a central synapse limits the acuity of visual perception in zebrafish.

P49678	IAA2_ARATH	Auxin-responsive protein IAA2	8278386	Early auxin-induced genes encode short-lived nuclear proteins.

Q62902	LMAN1_RAT	Protein ERGIC-53	11850423	Crystal structure of the carbohydrate recognition domain of p58/ERGIC-53, a protein involved in glycoprotein export from the endoplasmic reticulum.

O14626	GP171_HUMAN	Probable G-protein coupled receptor 171	9370294	A genetic selection for isolating cDNAs encoding secreted proteins.

Q9QUN7	TLR2_MOUSE	Toll-like receptor 2	17889651	Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide.

Q99447	PCY2_HUMAN	Ethanolamine-phosphate cytidylyltransferase	9083101	Cloning of a human cDNA for CTP-phosphoethanolamine cytidylyltransferase by complementation in vivo of a yeast mutant.

Q04175	SXM1_YEAST	Importin beta SMX1	9238021	Importin/karyopherin protein family members required for mRNA export from the nucleus.

Q9Y4C5	CHST2_HUMAN	Carbohydrate sulfotransferase 2	11042394	Functional expression and genomic structure of human N- acetylglucosamine-6-O-sulfotransferase that transfers sulfate to b-N- acetylglucosamine at the nonreducing end of an N-acetyllactosamine sequence.

Q9JLY0	SOCS6_MOUSE	Suppressor of cytokine signaling 6	12052866	SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation.

Q99MV5	M10L1_MOUSE	Putative helicase Mov10l1	11854500	Suppression of proliferation and cardiomyocyte hypertrophy by CHAMP, a cardiac-specific RNA helicase.

Q96IY4	CBPB2_HUMAN	Carboxypeptidase B2	1939207	Isolation, molecular cloning, and partial characterization of a novel carboxypeptidase B from human plasma.

P55034	PSMD4_ARATH	26S proteasome non-ATPase regulatory subunit 4	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

Q86UN2	R4RL1_HUMAN	Reticulon-4 receptor-like 1	14664809	Two novel mammalian nogo receptor homologs differentially expressed in the central and peripheral nervous systems.

Q9QXN4	MIOX_RAT	Inositol oxygenase	10944187	Identification of a renal-specific oxido-reductase in newborn diabetic mice.

P70331	MDFI_MOUSE	MyoD family inhibitor	11238923	Inhibition of Tcf3 binding by I-mfa domain proteins.

Q9NVV9	THAP1_HUMAN	THAP domain-containing protein 1	19182804	Mutations in the THAP1 gene are responsible for DYT6 primary torsion dystonia.

Q95VP2	GOBP2_EPIPO	General odorant-binding protein 2	12530222	Pheromone binding proteins of Epiphyas postvittana (Lepidoptera: Tortricidae) are encoded at a single locus.

O00327	BMAL1_HUMAN	Aryl hydrocarbon receptor nuclear translocator-like protein 1	9576906	The basic-helix-loop-helix-PAS orphan MOP3 forms transcriptionally active complexes with circadian and hypoxia factors.

Q6NLV4	FY_ARATH	Flowering time control protein FY	16033802	An allelic series reveals essential roles for FY in plant development in addition to flowering-time control.

O04046	GGPP2_ARATH	Geranylgeranyl pyrophosphate synthase 2	10759500	Five geranylgeranyl diphosphate synthases expressed in different organs are localized into three subcellular compartments in Arabidopsis.

P22199	MCR_RAT	Mineralocorticoid receptor	8618925	Steroid receptor heterodimerization demonstrated in vitro and in vivo.

Q9FT81	TT8_ARATH	Transcription factor TT8	11041882	The TT8 gene encodes a basic helix-loop-helix domain protein required for expression of DFR and BAN genes in Arabidopsis siliques.

Q00619	MAM2_SCHPO	Pheromone P-factor receptor	1657593	The Schizosaccharomyces pombe mam2 gene encodes a putative pheromone receptor which has a significant homology with the Saccharomyces cerevisiae Ste2 protein.

Q8K558	TRML1_MOUSE	Trem-like transcript 1 protein	15100151	A TREM family member, TLT-1, is found exclusively in the alpha- granules of megakaryocytes and platelets.

Q8MVS5	GLT35_DROME	Polypeptide N-acetylgalactosaminyltransferase 35A	11925446	A UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase is essential for viability in Drosophila melanogaster.

P32215	PACR_RAT	Pituitary adenylate cyclase-activating polypeptide type IA receptor	8396727	Differential signal transduction by five splice variants of the PACAP receptor.

Q9VM64	IHOG_DROME	Interference hedgehog	17077139	Structure of a heparin-dependent complex of Hedgehog and Ihog.

Q05201	EYA_DROME	Developmental protein eyes absent	14628053	The transcription factor Eyes absent is a protein tyrosine phosphatase.

P34149	RACC_DICDI	Rho-related protein racC	15509655	Cellular distribution and functions of wild-type and constitutively activated Dictyostelium PakB.

Q12154	GET3_YEAST	ATPase GET3	12680698	The Saccharomyces cerevisiae Arr4p is involved in metal and heat tolerance.

Q96GC6	ZN274_HUMAN	Zinc finger protein 274	10777669	Identification and characterization of human ZNF274 cDNA, Which encodes a novel kruppel-type zinc-finger protein having nucleolar targeting ability.

O74789	YOU5_SCHPO	Putative serine/threonine-protein phosphatase C26H8.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O18373	SPS1_DROME	Selenide, water dikinase	10444382	Disruption of selenoprotein biosynthesis affects cell proliferation in the imaginal discs and brain of Drosophila melanogaster.

Q62774	MYO1A_RAT	Myosin-Ia	7779104	Identification of brush border myosin-I in liver and testis.

P17516	AK1C4_HUMAN	Aldo-keto reductase family 1 member C4	2187532	Isolation and characterization of cloned cDNAs encoding human liver chlordecone reductase.

Q8VWG7	TDX_ARATH	TPR repeat-containing thioredoxin TDX	12433921	Redox control of Hsp70-Co-chaperone interaction revealed by expression of a thioredoxin-like Arabidopsis protein.

Q9FMW9	ICMTA_ARATH	Protein-S-isoprenylcysteine O-methyltransferase A	12472689	Prenylcysteine alpha-carboxyl methyltransferase expression and function in Arabidopsis thaliana.

P49723	RIR4_YEAST	Ribonucleoside-diphosphate reductase small chain 2	15196016	Structures of the yeast ribonucleotide reductase Rnr2 and Rnr4 homodimers.

O00257	CBX4_HUMAN	E3 SUMO-protein ligase CBX4	9315667	Interference with the expression of a novel human polycomb protein, hPc2, results in cellular transformation and apoptosis.

Q9NPA2	MMP25_HUMAN	Matrix metalloproteinase-25	10706098	Human MT6-matrix metalloproteinase: identification, progelatinase A activation, and expression in brain tumors.

Q04760	LGUL_HUMAN	Lactoylglutathione lyase	7684374	Human glyoxalase I. cDNA cloning, expression, and sequence similarity to glyoxalase I from Pseudomonas putida.

P80511	S10AC_HUMAN	Protein S100-A12	8619876	Host-parasite interaction in human onchocerciasis: identification and sequence analysis of a novel human calgranulin.

Q9NQ55	SSF1_HUMAN	Suppressor of SWI4 1 homolog	10944437	Cloning, genomic organization, and tissue distribution of human Ssf- 1.

P18898	PGTB1_YEAST	Geranylgeranyl transferase type-1 subunit beta	2034682	Protein geranylgeranyltransferase of Saccharomyces cerevisiae is specific for Cys-Xaa-Xaa-Leu motif proteins and requires the CDC43 gene product but not the DPR1 gene product.

Q969G6	RIFK_HUMAN	Riboflavin kinase	12623014	Crystal structure of human riboflavin kinase reveals a beta barrel fold and a novel active site arch.

P40055	UTP7_YEAST	U3 small nucleolar RNA-associated protein 7	12068309	A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis.

P87284	PMP3_YEAST	Plasma membrane proteolipid 3	10835350	Membrane hyperpolarization and salt sensitivity induced by deletion of PMP3, a highly conserved small protein of yeast plasma membrane.

Q07998	BRACA_DANRE	Brachyury protein homolog A	7600949	no tail (ntl) is the zebrafish homologue of the mouse T (Brachyury) gene.

O75146	HIP1R_HUMAN	Huntingtin-interacting protein 1-related protein	15533940	Huntingtin-interacting protein 1 (Hip1) and Hip1-related protein (Hip1R) bind the conserved sequence of clathrin light chains and thereby influence clathrin assembly in vitro and actin distribution in vivo.

P49895	IOD1_HUMAN	Type I iodothyronine deiodinase	1400883	Cloning and in vitro expression of the human selenoprotein, type I iodothyronine deiodinase.

P07153	RPN1_RAT	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1	3031084	Isolation and characterization of cDNA clones for rat ribophorin I: complete coding sequence and in vitro synthesis and insertion of the encoded product into endoplasmic reticulum membranes.

P35412	GPR12_MOUSE	G-protein coupled receptor 12	12574419	Role of the G-protein-coupled receptor GPR12 as high-affinity receptor for sphingosylphosphorylcholine and its expression and function in brain development.

P55786	PSA_HUMAN	Puromycin-sensitive aminopeptidase	10329370	Cloning and analysis of the gene for the human puromycin-sensitive aminopeptidase.

P20930	FILA_HUMAN	Filaggrin	2740331	Characterization of a cDNA clone encoding human filaggrin and localization of the gene to chromosome region 1q21.

Q04235	TYW2_YEAST	tRNA wybutosine-synthesizing protein 2	16005430	A novel methyltransferase required for the formation of the hypermodified nucleoside wybutosine in eucaryotic tRNA.

Q9DD24	WBP5_MOUSE	WW domain-binding protein 5	9171351	FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands.

Q9YGV1	DERR_XENLA	Derriere protein	12070085	Effects of heterodimerization and proteolytic processing on Derriere and Nodal activity: implications for mesoderm induction in Xenopus.

P05783	K1C18_HUMAN	Keratin, type I cytoskeletal 18	10954706	Identification of Mrj, a DnaJ/Hsp40 family protein, as a keratin 8/18 filament regulatory protein.

Q5MJ68	SPDYC_HUMAN	Speedy protein C	15611625	Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins.

Q9NWV8	MRI40_HUMAN	BRCA1-A complex subunit MERIT40	19261748	MERIT40 facilitates BRCA1 localization and DNA damage repair.

Q5B508	PGLRB_EMENI	Endopolygalacturonase B	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

P52657	T2AG_HUMAN	Transcription initiation factor IIA subunit 2	7958899	Molecular cloning of the small (gamma) subunit of human TFIIA reveals functions critical for activated transcription.

P39984	HAT2_YEAST	Histone acetyltransferase type B subunit 2	8858151	The major cytoplasmic histone acetyltransferase in yeast: links to chromatin replication and histone metabolism.

Q5SNZ0	GRDN_MOUSE	Girdin	15753085	A novel protein kinase B (PKB)/AKT-binding protein enhances PKB kinase activity and regulates DNA synthesis.

Q9NXR7	BRE_HUMAN	BRCA1-A complex subunit BRE	19214193	K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC- associated Brcc36 and proteasomal Poh1.

O35615	FOG1_MOUSE	Zinc finger protein ZFPM1	11940669	Interaction between FOG-1 and the corepressor C-terminal binding protein is dispensable for normal erythropoiesis in vivo.

Q9Y7S9	AMY3_SCHPO	Alpha-amylase 3	12845604	Genome-wide identification of fungal GPI proteins.

Q9Z258	KCNT1_RAT	Potassium channel subfamily T member 1	12628167	The sodium-activated potassium channel is encoded by a member of the Slo gene family.

Q99MY2	NUDT4_RAT	Diphosphoinositol polyphosphate phosphohydrolase 2	11331144	Molecular cloning of a novel isoform of diphosphoinositol polyphosphate phosphohydrolase: a potential target of lithium therapy.

P42818	KPK1_ARATH	Serine/threonine-protein kinase AtPK1/AtPK6	7828736	Two genes that encode ribosomal-protein S6 kinase homologs are induced by cold or salinity stress in Arabidopsis thaliana.

O14267	YFPC_SCHPO	Uncharacterized protein C7D4.12c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O54902	NRAM2_RAT	Natural resistance-associated macrophage protein 2	9242408	Cloning and characterization of a mammalian proton-coupled metal-ion transporter.

Q9NS23	RASF1_HUMAN	Ras association domain-containing protein 1	12024041	The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation.

P53538	SSU72_YEAST	RNA polymerase II subunit A C-terminal domain phosphatase SSU72	12819204	Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-ends.

Q9NU22	MDN1_HUMAN	Midasin	12102729	Expression and genomic analysis of midasin, a novel and highly conserved AAA protein distantly related to dynein.

P43629	KI3L1_HUMAN	Killer cell immunoglobulin-like receptor 3DL1	7650366	Molecular cloning of NKB1. A natural killer cell receptor for HLA-B allotypes.

Q9CTN5	S6OS1_MOUSE	Protein SIX6OS1	15703187	Natural antisense transcripts associated with genes involved in eye development.

P37637	MDTF_ECOLI	Multidrug resistance protein mdtF	11914367	EvgA of the two-component signal transduction system modulates production of the yhiUV multidrug transporter in Escherichia coli.

A5HNF6	MYD88_CHICK	Myeloid differentiation primary response protein MyD88	18582498	Molecular cloning and functional characterization of a novel isoform of chicken myeloid differentiation factor 88 (MyD88).

Q92547	TOPB1_HUMAN	DNA topoisomerase 2-binding protein 1	9461304	A DNA topoisomerase II binding protein with eight repeating regions similar to DNA repair enzymes and to a cell cycle regulator.

Q9VIP8	VLS_DROME	Protein valois	15634703	Drosophila valois encodes a divergent WD protein that is required for Vasa localization and Oskar protein accumulation.

Q02386	ZNF45_HUMAN	Zinc finger protein 45	1559709	The identification and characterization of KRAB-domain-containing zinc finger proteins.

Q9C566	CYP40_ARATH	Peptidyl-prolyl cis-trans isomerase CYP40	11264535	Regulation of vegetative phase change in Arabidopsis thaliana by cyclophilin 40.

Q54LV1	RAD23_DICDI	UV excision repair protein RAD23 homolog	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P23841	XAPR_ECOLI	HTH-type transcriptional regulator xapR	7559336	Identification and characterization of genes (xapA, xapB, and xapR) involved in xanthosine catabolism in Escherichia coli.

P17844	DDX5_HUMAN	Probable ATP-dependent RNA helicase DDX5	1996094	p68 RNA helicase: identification of a nucleolar form and cloning of related genes containing a conserved intron in yeasts.

Q78PB6	NDEL1_RAT	Nuclear distribution protein nudE-like 1	17035248	DISC1-NDEL1/NUDEL protein interaction, an essential component for neurite outgrowth, is modulated by genetic variations of DISC1.

P53039	YIP1_YEAST	Protein transport protein YIP1	15263065	The phox homology (PX) domain protein interaction network in yeast.

Q14493	SLBP_HUMAN	Histone RNA hairpin-binding protein	16086026	Regulated degradation of replication-dependent histone mRNAs requires both ATR and Upf1.

P56377	AP1S2_HUMAN	AP-1 complex subunit sigma-2	9733768	Identification and characterization of novel clathrin adaptor-related proteins.

P61980	HNRPK_RAT	Heterogeneous nuclear ribonucleoprotein K	8127654	Cloning and characterization of a single-stranded DNA binding protein that specifically recognizes deoxycytidine stretch.

Q6P9X9	PARM1_RAT	Prostate androgen-regulated mucin-like protein 1 homolog	12772192	Prostatic androgen repressed message-1 (PARM-1) may play a role in prostatic cell immortalisation.

P31689	DNJA1_HUMAN	DnaJ homolog subfamily A member 1	8334160	Cloning of a unique human homologue of the Escherichia coli DNAJ heat shock protein.

Q12431	EMC6_YEAST	Uncharacterized protein YLL014W	14562095	Global analysis of protein localization in budding yeast.

Q8CBD1	NRIP1_MOUSE	Nuclear receptor-interacting protein 1	11278635	Ligand-dependent formation of retinoid receptors, receptor- interacting protein 140 (RIP140), and histone deacetylase complex is mediated by a novel receptor-interacting motif of RIP140.

B3GS44	LRE_ARATH	GPI-anchored protein LORELEI	19028964	Maternal control of male-gamete delivery in Arabidopsis involves a putative GPI-anchored protein encoded by the LORELEI gene.

O13801	YE04_SCHPO	Uncharacterized RNA-binding protein C17H9.04c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q14123	PDE1C_HUMAN	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	8557689	Isolation and characterization of cDNAs corresponding to two human calcium, calmodulin-regulated, 3',5'-cyclic nucleotide phosphodiesterases.

Q80VW5	WHRN_MOUSE	Whirlin	15654330	Myosin-XVa is required for tip localization of whirlin and differential elongation of hair-cell stereocilia.

P31629	ZEP2_HUMAN	Transcription factor HIVEP2	2022670	HIV-EP2, a new member of the gene family encoding the human immunodeficiency virus type 1 enhancer-binding protein. Comparison with HIV-EP1/PRDII-BF1/MBP-1.

P35845	OSH1_YEAST	Oxysterol-binding protein homolog 1	15173322	A role for yeast oxysterol-binding protein homologs in endocytosis and in the maintenance of intracellular sterol-lipid distribution.

P80020	FABP6_RAT	Gastrotropin	8197128	Molecular cloning, tissue distribution, and expression of a 14-kDa bile acid-binding protein from rat ileal cytosol.

Q9H0H5	RGAP1_HUMAN	Rac GTPase-activating protein 1	16129829	MgcRacGAP controls the assembly of the contractile ring and the initiation of cytokinesis.

Q9NZH8	IL1F9_HUMAN	Interleukin-1 family member 9	10744718	Identification and initial characterization of four novel members of the interleukin-1 family.

P15425	CYPR_DROME	Peptidyl-prolyl cis-trans isomerase, rhodopsin-specific isozyme	1707759	The cyclophilin homolog ninaA is a tissue-specific integral membrane protein required for the proper synthesis of a subset of Drosophila rhodopsins.

P19941	GHR_RABIT	Growth hormone receptor	2825030	Growth hormone receptor and serum binding protein: purification, cloning and expression.

Q38829	IAA11_ARATH	Auxin-responsive protein IAA11	12036262	Genetics of Aux/IAA and ARF action in plant growth and development.

Q3UHN9	NDST1_MOUSE	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1	10852901	Defective heparan sulfate biosynthesis and neonatal lethality in mice lacking N-deacetylase/N-sulfotransferase-1.

Q91VF5	EMID1_MOUSE	EMI domain-containing protein 1	12221002	Developmental expression and biochemical characterization of Emu family members.

O22476	BRI1_ARATH	Protein BRASSINOSTEROID INSENSITIVE 1	16473966	The Arabidopsis SOMATIC EMBRYOGENESIS RECEPTOR-LIKE KINASE1 protein complex includes BRASSINOSTEROID-INSENSITIVE1.

Q80U72	SCRIB_MOUSE	Protein scribble homolog	18716323	Scrib regulates PAK activity during the cell migration process.

Q05498	FCF1_YEAST	rRNA-processing protein FCF1	16762320	Fcf1p and Fcf2p are novel nucleolar Saccharomyces cerevisiae proteins involved in pre-rRNA processing.

Q652A1	IAA26_ORYSJ	Auxin-responsive protein IAA26	16200395	Structure and expression analysis of early auxin-responsive Aux/IAA gene family in rice (Oryza sativa).

P14649	MYL6B_HUMAN	Myosin light chain 6B	2304459	Characterization of human myosin light chains 1sa and 3nm: implications for isoform evolution and function.

O65718	CNGC2_ARATH	Cyclic nucleotide-gated ion channel 2	10900264	The Arabidopsis dnd1 'defense, no death' gene encodes a mutated cyclic nucleotide-gated ion channel.

Q6R3L0	YSL1_ARATH	Metal-nicotianamine transporter YSL1	16297069	A loss-of-function mutation in AtYSL1 reveals its role in iron and nicotianamine seed loading.

Q12766	HMGX3_HUMAN	HMG domain-containing protein 3	9027509	Sequence analysis of two genomic regions containing the KIT and the FMS receptor tyrosine kinase genes.

O08747	UNC5C_MOUSE	Netrin receptor UNC5C	9126743	The mouse rostral cerebellar malformation gene encodes an UNC-5-like protein.

Q9NZV7	ZIM2_HUMAN	Zinc finger imprinted 2	10708526	Exon sharing of a novel human zinc-finger gene, ZIM2, and paternally expressed gene 3 (PEG3).

Q56061	SIFA_SALTY	Secreted effector protein sifA	15905402	The intracellular fate of Salmonella depends on the recruitment of kinesin.

P63104	1433Z_HUMAN	14-3-3 protein zeta/delta	15696159	JNK phosphorylation of 14-3-3 proteins regulates nuclear targeting of c-Abl in the apoptotic response to DNA damage.

Q7Z4G1	COMD6_HUMAN	COMM domain-containing protein 6	15799966	COMMD proteins, a novel family of structural and functional homologs of MURR1.

Q9XTC6	MOM4_CAEEL	Mitogen-activated protein kinase kinase kinase mom-4	16077004	Wnt signaling drives WRM-1/beta-catenin asymmetries in early C. elegans embryos.

Q99581	FEV_HUMAN	Protein FEV	9121764	A new member of the ETS family fused to EWS in Ewing tumors.

Q03262	PGM3_YEAST	Phosphoglucomutase YMR278W	14562095	Global analysis of protein localization in budding yeast.

Q9S7I6	RPK2_ARATH	LRR receptor-like serine/threonine-protein kinase RPK2	17543866	RPK1 and TOAD2 are two receptor-like kinases redundantly required for arabidopsis embryonic pattern formation.

Q3U1U7	AHRR_MOUSE	Aryl hydrocarbon receptor repressor	9887096	Identification of a novel mechanism of regulation of Ah (dioxin) receptor function.

Q62696	DLG1_RAT	Disks large homolog 1	7891172	Molecular characterization and spatial distribution of SAP97, a novel presynaptic protein homologous to SAP90 and the Drosophila discs-large tumor suppressor protein.

P63033	RHES_RAT	GTP-binding protein Rhes	10467249	Rhes: a striatal-specific Ras homolog related to Dexras1.

P61952	GBG11_HUMAN	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11	7665596	Isolation of cDNA clones encoding eight different human G protein gamma subunits, including three novel forms designated the gamma 4, gamma 10, and gamma 11 subunits.

Q9LZM8	BLH9_ARATH	BEL1-like homeodomain protein 9	15155890	Repression of AGAMOUS by BELLRINGER in floral and inflorescence meristems.

P49815	TSC2_HUMAN	Tuberin	10585443	Characterization of the cytosolic tuberin-hamartin complex. Tuberin is a cytosolic chaperone for hamartin.

P47161	VPS70_YEAST	Vacuolar protein sorting-associated protein 70	12134085	Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae.

Q9UKU6	TRHDE_HUMAN	Thyrotropin-releasing hormone-degrading ectoenzyme	10491199	Human TRH-degrading ectoenzyme cDNA cloning, functional expression, genomic structure and chromosomal assignment.

O94806	KPCD3_HUMAN	Serine/threonine-protein kinase D3	10231560	PKCnu, a new member of the protein kinase C family, composes a fourth subfamily with PKCmu.

Q01617	CPO_DROME	Protein couch potato	1427076	The Drosophila couch potato protein is expressed in nuclei of peripheral neuronal precursors and shows homology to RNA-binding proteins.

Q99616	CCL13_HUMAN	C-C motif chemokine 13	9195948	Cloning, in vitro expression, and functional characterization of a novel human CC chemokine of the monocyte chemotactic protein (MCP) family (MCP-4) that binds and signals through the CC chemokine receptor 2B.

Q9BUP3	HTAI2_HUMAN	Oxidoreductase HTATIP2	15282309	Inhibition of nuclear import by the proapoptotic protein CC3.

P40072	SLX8_YEAST	E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX8	11139495	Requirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiae.

P52847	ST1B1_RAT	Sulfotransferase family cytosolic 1B member 1	8530477	Purification, characterization, and molecular cloning of a novel rat liver Dopa/tyrosine sulfotransferase.

P23301	IF5A1_YEAST	Eukaryotic translation initiation factor 5A-1	19120453	Dimerization of the yeast eukaryotic translation initiation factor 5A requires hypusine and is RNA dependent.

P54923	ADPRH_MOUSE	[Protein ADP-ribosylarginine] hydrolase	8349667	Cloning and site-directed mutagenesis of human ADP-ribosylarginine hydrolase.

P60201	MYPR_HUMAN	Myelin proteolipid protein	2479017	Mutation of the proteolipid protein gene PLP in a human X chromosome- linked myelin disorder.

P13716	HEM2_HUMAN	Delta-aminolevulinic acid dehydratase	11032836	The molecular mechanism of lead inhibition of human porphobilinogen synthase.

P41940	MPG1_YEAST	Mannose-1-phosphate guanyltransferase	9195935	Saccharomyces cerevisiae VIG9 encodes GDP-mannose pyrophosphorylase, which is essential for protein glycosylation.

Q9H305	LITFL_HUMAN	LITAF-like protein	17599062	CDIP, a novel pro-apoptotic gene, regulates TNFalpha-mediated apoptosis in a p53-dependent manner.

Q8CDB0	MKNK2_MOUSE	MAP kinase-interacting serine/threonine-protein kinase 2	9155017	Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2.

Q9Y2T3	GUAD_HUMAN	Guanine deaminase	10075721	Cloning and characterization of human guanine deaminase. Purification and partial amino acid sequence of the mouse protein.

Q8T869	BIP2_DICDI	Luminal-binding protein 2	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q16512	PKN1_HUMAN	Serine/threonine-protein kinase N1	20228790	Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4.

P36929	RSMB_ECOLI	Ribosomal RNA small subunit methyltransferase B	10194318	Identification of the 16S rRNA m5C967 methyltransferase from Escherichia coli.

Q9UQ90	SPG7_HUMAN	Paraplegin	9635427	Spastic paraplegia and OXPHOS impairment caused by mutations in paraplegin, a nuclear-encoded mitochondrial metalloprotease.

O55091	IMPCT_MOUSE	Protein IMPACT	15937339	IMPACT, a protein preferentially expressed in the mouse brain, binds GCN1 and inhibits GCN2 activation.

Q9VUM0	MSH6_DROME	Probable DNA mismatch repair protein Msh6	17339220	Meiotic recombination in Drosophila Msh6 mutants yields discontinuous gene conversion tracts.

Q09884	DCR1_SCHPO	Protein Dicer	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P70412	CUZD1_MOUSE	CUB and zona pellucida-like domain-containing protein 1	12401800	Protection from pancreatitis by the zymogen granule membrane protein integral membrane-associated protein-1.

P46609	KNOS6_ORYSJ	Homeobox protein knotted-1-like 6	8104574	Expression of a rice homeobox gene causes altered morphology of transgenic plants.

P32561	RPD3_YEAST	Histone deacetylase RPD3	8962081	HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription.

Q9H061	T126A_HUMAN	Transmembrane protein 126A	19327736	TMEM126A, encoding a mitochondrial protein, is mutated in autosomal- recessive nonsyndromic optic atrophy.

Q9SGS4	CDSP_ARATH	Thioredoxin-like protein CDSP32, chloroplastic	19259774	A novel extended family of stromal thioredoxins.

Q9EQF5	DPYS_MOUSE	Dihydropyrimidinase	10956643	Molecular characterization of CRMP5, a novel member of the collapsin response mediator protein family.

Q03920	MTQ2_YEAST	eRF1 methyltransferase catalytic subunit MTQ2	16321977	The yeast translation release factors Mrf1p and Sup45p (eRF1) are methylated, respectively, by the methyltransferases Mtq1p and Mtq2p.

Q06704	IMH1_YEAST	Golgin IMH1	15077113	Targeting of the Arf-like GTPase Arl3p to the Golgi requires N- terminal acetylation and the membrane protein Sys1p.

Q9PUK8	FZD7A_XENLA	Frizzled-7-A	10990458	The C-terminal cytoplasmic Lys-Thr-X-X-X-Trp motif in frizzled receptors mediates Wnt/beta-catenin signalling.

P29056	TF3B_YEAST	Transcription factor IIIB 70 kDa subunit	1423590	A suppressor of TBP mutations encodes an RNA polymerase III transcription factor with homology to TFIIB.

P39713	BDH2_YEAST	Probable diacetyl reductase [(R)-acetoin forming] 2	14562095	Global analysis of protein localization in budding yeast.

Q9Y608	LRRF2_HUMAN	Leucine-rich repeat flightless-interacting protein 2	10366446	Novel proteins interacting with the leucine-rich repeat domain of human flightless-I identified by the yeast two-hybrid system.

Q9UT94	MTQ2_SCHPO	eRF1 methyltransferase catalytic subunit mtq2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q1K9C4	YFK7_SCHPO	Probable E3 ubiquitin protein ligase C167.07c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P59511	ATS20_MOUSE	A disintegrin and metalloproteinase with thrombospondin motifs 20	12562771	Identification and characterization of ADAMTS-20 defines a novel subfamily of metalloproteinases-disintegrins with multiple thrombospondin-1 repeats and a unique GON domain.

Q9LQ55	DRP2B_ARATH	Dynamin-2B	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q8RXD6	BRE1A_ARATH	E3 ubiquitin-protein ligase BRE1-like 1	17329565	The Arabidopsis thaliana homolog of yeast BRE1 has a function in cell cycle regulation during early leaf and root growth.

Q13219	PAPP1_HUMAN	Pappalysin-1	10913121	Expression of recombinant human pregnancy-associated plasma protein-A and identification of the proform of eosinophil major basic protein as its physiological inhibitor.

P49221	TGM4_HUMAN	Protein-glutamine gamma-glutamyltransferase 4	7916568	Molecular cloning and characterization of a novel transglutaminase cDNA from a human prostate cDNA library.

P32056	NUDD_ECOLI	GDP-mannose mannosyl hydrolase	12196023	Mutational, kinetic, and NMR studies of the mechanism of E. coli GDP- mannose mannosyl hydrolase, an unusual Nudix enzyme.

Q61337	BAD_MOUSE	Bcl2 antagonist of cell death	7834748	Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death.

Q9EQG3	SCEL_MOUSE	Sciellin	11112355	Gene characterization of sciellin (SCEL) and protein localization in vertebrate epithelia displaying barrier properties.

Q7KTX8	MED13_DROME	Mediator of RNA polymerase II transcription subunit 13	17290221	Distinct roles for Mediator Cdk8 module subunits in Drosophila development.

P55085	PAR2_HUMAN	Proteinase-activated receptor 2	8615752	Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2.

Q90WY4	ADA2A_DANRE	Alpha-2A adrenergic receptor	15655522	Conserved structural, pharmacological and functional properties among the three human and five zebrafish alpha2-adrenoceptors.

Q9UQF2	JIP1_HUMAN	C-Jun-amino-terminal kinase-interacting protein 1	11726277	Mixed lineage kinase LZK forms a functional signaling complex with JIP-1, a scaffold protein of the c-Jun NH(2)-terminal kinase pathway.

P05319	RLA2_YEAST	60S acidic ribosomal protein P2-alpha	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q99678	GPR20_HUMAN	G-protein coupled receptor 20	9073069	Cloning and chromosomal mapping of four putative novel human G- protein-coupled receptor genes.

P15047	ENTA_ECOLI	2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase	2521622	Nucleotide sequence of a cluster of Escherichia coli enterobactin biosynthesis genes: identification of entA and purification of its product 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase.

Q8RWN0	ULP1C_ARATH	Ubiquitin-like-specific protease 1C	16740136	Evolution of a signalling system that incorporates both redundancy and diversity: Arabidopsis SUMOylation.

P38883	RIX1_YEAST	Pre-rRNA-processing protein RIX1	11313466	Nuclear export of 60s ribosomal subunits depends on Xpo1p and requires a nuclear export sequence-containing factor, Nmd3p, that associates with the large subunit protein Rpl10p.

P05783	K1C18_HUMAN	Keratin, type I cytoskeletal 18	11684708	Keratin attenuates tumor necrosis factor-induced cytotoxicity through association with TRADD.

O75593	FOXH1_HUMAN	Forkhead box protein H1	9702198	Characterization of human FAST-1, a TGF beta and activin signal transducer.

P38784	VMA22_YEAST	Vacuolar ATPase assembly protein VMA22	7673216	Vma22p is a novel endoplasmic reticulum-associated protein required for assembly of the yeast vacuolar H(+)-ATPase complex.

P83175	HCYB_CANPG	Hemocyanin subunit B	2620501	The relationship between N-terminal sequences and immunological characterization of crustacean hemocyanins.

Q8IN58	GR92A_DROME	Putative gustatory receptor 92a	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

Q9T2K9	CB22_SPIOL	Chlorophyll a-b binding protein	1894641	Tandem mass spectrometry identifies sites of three post-translational modifications of spinach light-harvesting chlorophyll protein II. Proteolytic cleavage, acetylation, and phosphorylation.

P09917	LOX5_HUMAN	Arachidonate 5-lipoxygenase	8245774	5-lipoxygenase and 5-lipoxygenase-activating protein are localized in the nuclear envelope of activated human leukocytes.

Q96FM1	PGAP3_HUMAN	Post-GPI attachment to proteins factor 3	17021251	PER1 is required for GPI-phospholipase A2 activity and involved in lipid remodeling of GPI-anchored proteins.

P10745	RET3_HUMAN	Retinol-binding protein 3	2542268	Human interstitial retinoid-binding protein. Gene structure and primary structure.

P83344	XYNB_PRUPE	Putative beta-D-xylosidase	11847241	Ethylene-responsive genes are differentially regulated during abscission, organ senescence and wounding in peach (Prunus persica).

Q24498	RY44_DROME	Ryanodine receptor 44F	8276118	Isolation and characterization of a gene for a ryanodine receptor/calcium release channel in Drosophila melanogaster.

Q9QUK5	HSPB7_RAT	Heat shock protein beta-7	10593960	Identification and characterization of cvHsp. A novel human small stress protein selectively expressed in cardiovascular and insulin- sensitive tissues.

O35716	SOCS1_MOUSE	Suppressor of cytokine signaling 1	9202126	A new protein containing an SH2 domain that inhibits JAK kinases.

Q9NZM1	MYOF_HUMAN	Myoferlin	18502764	The endocytic recycling protein EHD2 interacts with myoferlin to regulate myoblast fusion.

P25358	ELO2_YEAST	Elongation of fatty acids protein 2	9832547	Involvement of long chain fatty acid elongation in the trafficking of secretory vesicles in yeast.

P43432	IL12B_MOUSE	Interleukin-12 subunit beta	11114383	Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12.

Q8IUG5	MY18B_HUMAN	Myosin-XVIIIb	12547197	Human MYO18B, a novel unconventional myosin heavy chain expressed in striated muscles moves into the myonuclei upon differentiation.

A8K2U0	A2ML1_HUMAN	Alpha-2-macroglobulin-like protein 1	16298998	A novel protease inhibitor of the alpha2-macroglobulin family expressed in the human epidermis.

P0A769	MNTH_ECOLI	Manganese transport protein mntH	14607838	Determination of transmembrane topology of the Escherichia coli natural resistance-associated macrophage protein (Nramp) ortholog.

Q8CF90	MAFA_MOUSE	Transcription factor MafA	12368292	MafA is a glucose-regulated and pancreatic beta-cell-specific transcriptional activator for the insulin gene.

P39678	MBP1_YEAST	Transcription factor MBP1	8372350	A role for the transcription factors Mbp1 and Swi4 in progression from G1 to S phase.

P53801	PTTG_HUMAN	Pituitary tumor-transforming gene 1 protein-interacting protein	10781616	A novel binding factor facilitates nuclear translocation and transcriptional activation function of the pituitary tumor- transforming gene product.

Q06416	P5F1B_HUMAN	Putative POU domain, class 5, transcription factor 1B	1408763	Human Oct3 gene family: cDNA sequences, alternative splicing, gene organization, chromosomal location, and expression at low levels in adult tissues.

Q07471	THI3_YEAST	Thiamine metabolism regulatory protein THI3	12499363	The catabolism of amino acids to long chain and complex alcohols in Saccharomyces cerevisiae.

P04801	SYTC_YEAST	Threonyl-tRNA synthetase, cytoplasmic	2995918	Cloning and characterization of the gene for the yeast cytoplasmic threonyl-tRNA synthetase.

Q9W596	FUTSC_DROME	Microtubule-associated protein futsch	10839355	Drosophila Futsch/22C10 is a MAP1B-like protein required for dendritic and axonal development.

Q8BKA3	SRRM4_MOUSE	Serine/arginine repetitive matrix protein 4	19737518	Regulation of vertebrate nervous system alternative splicing and development by an SR-related protein.

Q8IYF1	ELOA2_HUMAN	RNA polymerase II transcription factor SIII subunit A2	10692460	Identification and characterization of Elongin A2, a new member of the Elongin family of transcription elongation factors, specifically expressed in the testis.

Q9VA70	NCASE_DROME	Neutral ceramidase	12153720	Molecular cloning and characterization of a secretory neutral ceramidase of Drosophila melanogaster.

Q969X5	ERGI1_HUMAN	Endoplasmic reticulum-Golgi intermediate compartment protein 1	15308636	Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46.

Q15077	P2RY6_HUMAN	P2Y purinoceptor 6	8670200	Cloning, functional expression and tissue distribution of the human P2Y6 receptor.

O00194	RB27B_HUMAN	Ras-related protein Rab-27B	9066979	Molecular cloning and characterization of rab27a and rab27b, novel human rab proteins shared by melanocytes and platelets.

O95497	VNN1_HUMAN	Pantetheinase	11491533	Vanin genes are clustered (human 6q22-24 and mouse 10A2B1) and encode isoforms of pantetheinase ectoenzymes.

O14462	SEC4_CANAL	Ras-related protein SEC4	9639314	Isolation and characterization of the Candida albicans SEC4 gene.

P52435	RPB11_HUMAN	DNA-directed RNA polymerase II subunit RPB11-a	8797801	Cloning of a novel human RNA polymerase II subunit downregulated by doxorubicin: new potential mechanisms of drug related toxicity.

Q9Y2V3	RX_HUMAN	Retinal homeobox protein Rx	10625658	Both PCE-1/RX and OTX/CRX interactions are necessary for photoreceptor-specific gene expression.

Q9WVS0	ICOS_MOUSE	Inducible T-cell costimulator	10760791	Molecular cloning and characterization of murine ICOS and identification of B7h as ICOS ligand.

Q9UR09	PSU1_SCHPO	Cell wall synthesis protein psu1	10462482	Cloning and characterization of psu1+, a new essential fission yeast gene involved in cell wall synthesis.

P42772	CDN2B_HUMAN	Cyclin-dependent kinase 4 inhibitor B	8078588	p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest.

P06768	RET2_RAT	Retinol-binding protein 2	3029082	The cellular retinol binding protein II gene. Sequence analysis of the rat gene, chromosomal localization in mice and humans, and documentation of its close linkage to the cellular retinol binding protein gene.

P24043	LAMA2_HUMAN	Laminin subunit alpha-2	2185464	Merosin, a tissue-specific basement membrane protein, is a laminin- like protein.

Q9UIW0	VAX2_HUMAN	Ventral anterior homeobox 2	10485894	A homeobox gene, vax2, controls the patterning of the eye dorsoventral axis.

Q61508	ECM1_MOUSE	Extracellular matrix protein 1	7608209	Molecular cloning, characterization, and genetic mapping of the cDNA coding for a novel secretory protein of mouse. Demonstration of alternative splicing in skin and cartilage.

Q99MS0	S14L2_RAT	SEC14-like protein 2	11226224	Supernatant protein factor, which stimulates the conversion of squalene to lanosterol, is a cytosolic squalene transfer protein and enhances cholesterol biosynthesis.

P41183	BCL6_MOUSE	B-cell lymphoma 6 protein homolog	9632807	BAZF, a novel Bcl6 homolog, functions as a transcriptional repressor.

Q13133	NR1H3_HUMAN	Oxysterols receptor LXR-alpha	7744246	LXR, a nuclear receptor that defines a distinct retinoid response pathway.

Q05777	YL194_YEAST	Cell wall protein YLR194C	10383953	Amino acid residues in the omega-minus region participate in cellular localization of yeast glycosylphosphatidylinositol-attached proteins.

Q96RL1	UIMC1_HUMAN	BRCA1-A complex subunit RAP80	19261748	MERIT40 facilitates BRCA1 localization and DNA damage repair.

P53944	MTQ1_YEAST	Mitochondrial N(5)-glutamine methyltransferase MTQ1	16321977	The yeast translation release factors Mrf1p and Sup45p (eRF1) are methylated, respectively, by the methyltransferases Mtq1p and Mtq2p.

Q03940	RUVB1_YEAST	RuvB-like protein 1	14645854	ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex.

Q16594	TAF9_HUMAN	Transcription initiation factor TFIID subunit 9	9674425	Histone-like TAFs within the PCAF histone acetylase complex.

Q08971	YP225_YEAST	UPF0368 protein YPL225W	14562095	Global analysis of protein localization in budding yeast.

P12023	A4_MOUSE	Amyloid beta A4 protein	16314516	Amyloid precursor proteins anchor CPEB to membranes and promote polyadenylation-induced translation.

Q12366	NDJ1_YEAST	Non-disjunction protein 1	11018056	Meiotic telomere protein Ndj1p is required for meiosis-specific telomere distribution, bouquet formation and efficient homologue pairing.

Q05583	CIAO1_YEAST	Cytosolic iron-sulfur protein assembly protein 1	16314508	The essential WD40 protein Cia1 is involved in a late step of cytosolic and nuclear iron-sulfur protein assembly.

O88509	DNM3B_MOUSE	DNA (cytosine-5)-methyltransferase 3B	15456878	The PWWP domain of Dnmt3a and Dnmt3b is required for directing DNA methylation to the major satellite repeats at pericentric heterochromatin.

Q6YGZ1	HPSE_MOUSE	Heparanase	10395326	Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis.

P55205	GUC2G_RAT	Guanylate cyclase 2G	9422765	The cloning and expression of a new guanylyl cyclase orphan receptor.

P51532	SMCA4_HUMAN	Transcription activator BRG1	9590696	Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex.

Q9M354	AGD6_ARATH	Probable ADP-ribosylation factor GTPase-activating protein AGD6	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

P49739	MCM3M_XENLA	Maternal DNA replication licensing factor mcm3	8816774	XMCM7, a novel member of the Xenopus MCM family, interacts with XMCM3 and colocalizes with it throughout replication.

O60244	MED14_HUMAN	Mediator of RNA polymerase II transcription subunit 14	9989412	The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1.

P08542	UDB17_RAT	UDP-glucuronosyltransferase 2B17	3110162	Rat liver UDP-glucuronosyltransferase. Identification of cDNAs encoding two enzymes which glucuronidate testosterone, dihydrotestosterone, and beta-estradiol.

Q921E6	EED_MOUSE	Polycomb protein EED	15916951	The murine polycomb group protein Eed is required for global histone H3 lysine-27 methylation.

Q96QK1	VPS35_HUMAN	Vacuolar protein sorting-associated protein 35	11102511	Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: assembly into multimeric complexes.

P16110	LEG3_MOUSE	Galectin-3	10745073	Interaction of a novel cysteine and histidine-rich cytoplasmic protein with galectin-3 in a carbohydrate-independent manner galectin 3.

Q9UBN7	HDAC6_HUMAN	Histone deacetylase 6	12024216	HDAC6 is a microtubule-associated deacetylase.

Q80Z71	TENN_MOUSE	Tenascin-N	12812753	Tenascin-N: characterization of a novel member of the tenascin family that mediates neurite repulsion from hippocampal explants.

P38356	BSD2_YEAST	Metal homeostatis protein BSD2	9988727	Post-translation control of Nramp metal transport in yeast. Role of metal ions and the BSD2 gene.

P70269	CATE_MOUSE	Cathepsin E	11719510	Involvement of cathepsin E in exogenous antigen processing in primary cultured murine microglia.

Q07617	SPAG1_HUMAN	Sperm-associated antigen 1	1299558	Isolation and sequencing of the cDNA encoding the 75-kD human sperm protein related to infertility.

Q9DBR1	XRN2_MOUSE	5'-3' exoribonuclease 2	7885830	Characterization of cDNA encoding mouse homolog of fission yeast dhp1+ gene: structural and functional conservation.

P40694	SMBP2_MOUSE	DNA-binding protein SMUBP-2	19299493	Biochemical and genetic evidence for a role of IGHMBP2 in the translational machinery.

O94383	SMC1_SCHPO	Structural maintenance of chromosomes protein 1	11069892	Characterization of fission yeast cohesin: essential anaphase proteolysis of Rad21 phosphorylated in the S phase.

P20908	CO5A1_HUMAN	Collagen alpha-1(V) chain	9042913	Mutations in the COL5A1 gene are causal in the Ehlers-Danlos syndromes I and II.

Q62991	SCFD1_RAT	Sec1 family domain-containing protein 1	8663406	Mammalian Sly1 regulates syntaxin 5 function in endoplasmic reticulum to Golgi transport.

Q9VCU9	DCR1_DROME	Endoribonuclease Dcr-1	12368261	A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins.

P26687	TWST1_MOUSE	Twist-related protein 1	17893140	Mechanism of transcriptional activation by the proto-oncogene Twist1.

O00175	CCL24_HUMAN	C-C motif chemokine 24	9104803	Molecular and functional characterization of two novel human C-C chemokines as inhibitors of two distinct classes of myeloid progenitors.

Q6IRB2	HES1A_XENLA	Transcription factor HES-1-A	14648848	Identification of BOIP, a novel cDNA highly expressed during spermatogenesis that encodes a protein interacting with the orange domain of the hairy-related transcription factor HRT1/Hey1 in Xenopus and mouse.

P07647	KLK9_RAT	Submandibular glandular kallikrein-9	1900513	A novel serine protease with vasoconstrictor activity coded by the kallikrein gene S3.

Q15011	HERP1_HUMAN	Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein	18656546	Ubxd1 is a novel co-factor of the human p97 ATPase.

Q06078	UTP21_YEAST	U3 small nucleolar RNA-associated protein 21	15590835	The small-subunit processome is a ribosome assembly intermediate.

P47001	CIS3_YEAST	Cell wall mannoprotein CIS3	10407261	Role of NaOH-extractable cell wall proteins Ccw5p, Ccw6p, Ccw7p and Ccw8p (members of the Pir protein family) in stability of the Saccharomyces cerevisiae cell wall.

Q99PV8	BC11B_MOUSE	B-cell lymphoma/leukemia 11B	12717433	Bcl11b is required for differentiation and survival of alphabeta T lymphocytes.

Q925G0	RBM3_RAT	Putative RNA-binding protein 3	17403028	Two isoforms of the cold-inducible mRNA-binding protein RBM3 localize to dendrites and promote translation.

P63005	LIS1_MOUSE	Platelet-activating factor acetylhydrolase IB subunit alpha	14578885	Interaction of reelin signaling and Lis1 in brain development.

O43390	HNRPR_HUMAN	Heterogeneous nuclear ribonucleoprotein R	9421497	Molecular definition of heterogeneous nuclear ribonucleoprotein R (hnRNP R) using autoimmune antibody: immunological relationship with hnRNP P.

O75882	ATRN_HUMAN	Attractin	9736737	Attractin (DPPT-L), a member of the CUB family of cell adhesion and guidance proteins, is secreted by activated human T lymphocytes and modulates immune cell interactions.

B0M0P5	DDB1_DICDI	DNA damage-binding protein 1	9649625	Rapid changes of nucleotide excision repair gene expression following UV-irradiation and cisplatin treatment of Dictyostelium discoideum.

Q02435	BFSP1_RAT	Filensin	1378722	cDNA sequence analysis of CP94: rat lens fiber cell beaded-filament structural protein shows homology to cytokeratins.

Q61666	HIRA_MOUSE	Protein HIRA	15922569	Asymmetry in histone H3 variants and lysine methylation between paternal and maternal chromatin of the early mouse zygote.

P11349	NARH_ECOLI	Respiratory nitrate reductase 1 beta chain	8664273	Complete coordination of the four Fe-S centers of the beta subunit from Escherichia coli nitrate reductase. Physiological, biochemical, and EPR characterization of site-directed mutants lacking the highest or lowest potential [4Fe-4S] clusters.

P52194	CLGN_MOUSE	Calmegin	8188695	Molecular cloning and sequencing of calnexin-t. An abundant male germ cell-specific calcium-binding protein of the endoplasmic reticulum.

P34144	RAC1A_DICDI	Rho-related protein rac1A	9487125	DdLIM is a cytoskeleton-associated protein involved in the protrusion of lamellipodia in Dictyostelium.

P32905	RSSA1_YEAST	40S ribosomal protein S0-A	8626693	Yeast proteins related to the p40/laminin receptor precursor are essential components of the 40 S ribosomal subunit.

Q8GW19	FACE2_ARATH	CAAX prenyl protease 2	12928436	AtFACE-2, a functional prenylated protein protease from Arabidopsis thaliana related to mammalian Ras-converting enzymes.

Q99638	RAD9A_HUMAN	Cell cycle checkpoint control protein RAD9A	10846170	HDAC1, a histone deacetylase, forms a complex with Hus1 and Rad9, two G2/M checkpoint Rad proteins.

Q9UHJ6	SHPK_HUMAN	Sedoheptulokinase	10673275	The genomic region encompassing the nephropathic cystinosis gene (CTNS): complete sequencing of a 200-kb segment and discovery of a novel gene within the common cystinosis-causing deletion.

Q96EF6	FBX17_HUMAN	F-box only protein 17	18203720	Diversity in tissue expression, substrate binding, and SCF complex formation for a lectin family of ubiquitin ligases.

Q9UBR5	CKLF_HUMAN	Chemokine-like factor	11415443	Molecular cloning and characterization of chemokine-like factor 1 (CKLF1), a novel human cytokine with unique structure and potential chemotactic activity.

P36613	CGM2_SCHPO	Cyclin mcs2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O94691	JMJ3_SCHPO	Lid2 complex component jmj3	12488447	High conservation of the Set1/Rad6 axis of histone 3 lysine 4 methylation in budding and fission yeasts.

Q86C65	TOR_DICDI	Target of rapamycin	16079174	TOR complex 2 integrates cell movement during chemotaxis and signal relay in Dictyostelium.

P20648	ATP4A_HUMAN	Potassium-transporting ATPase alpha chain 1	2160952	Human gastric (H+ + K+)-ATPase gene. Similarity to (Na+ + K+)-ATPase genes in exon/intron organization but difference in control region.

Q15648	MED1_HUMAN	Mediator of RNA polymerase II transcription subunit 1	12218053	A coregulatory role for the TRAP-mediator complex in androgen receptor-mediated gene expression.

Q9VEZ5	IKKB_DROME	Inhibitor of nuclear factor kappa-B kinase subunit beta	10636911	Lipopolysaccharide-activated kinase, an essential component for the induction of the antimicrobial peptide genes in Drosophila melanogaster cells.

Q8QFX6	NRP1A_DANRE	Neuropilin-1a	12142468	Neuropilin-1 is required for vascular development and is a mediator of VEGF-dependent angiogenesis in zebrafish.

Q9HE11	UTP5_SCHPO	U3 small nucleolar RNA-associated protein 5	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P07948	LYN_HUMAN	Tyrosine-protein kinase Lyn	16467205	Integrin inhibition through Lyn-dependent cross talk from CXCR4 chemokine receptors in normal human CD34+ marrow cells.

P32939	YPT7_YEAST	GTP-binding protein YPT7	11943201	Identification of the novel proteins Yip4p and Yip5p as Rab GTPase interacting factors.

P05997	CO5A2_HUMAN	Collagen alpha-2(V) chain	9425231	Mutations of the alpha2(V) chain of type V collagen impair matrix assembly and produce Ehlers-Danlos syndrome type I.

Q5VYS8	TUT7_HUMAN	Terminal uridylyltransferase 7	17353264	Efficient RNA polyuridylation by noncanonical poly(A) polymerases.

P07713	DECA_DROME	Protein decapentaplegic	9695953	decapentaplegic is essential for the maintenance and division of germline stem cells in the Drosophila ovary.

O13760	YF2A_SCHPO	Uncharacterized membrane protein C17A2.10c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q80TJ1	CAPS1_MOUSE	Calcium-dependent secretion activator 1	15820695	CAPS1 regulates catecholamine loading of large dense-core vesicles.

P00813	ADA_HUMAN	Adenosine deaminase	3182793	Mutant human adenosine deaminase alleles and their expression by transfection into fibroblasts.

Q62696	DLG1_RAT	Disks large homolog 1	19213956	Kv4 potassium channels form a tripartite complex with the anchoring protein SAP97 and CaMKII in cardiac myocytes.

P63171	DYLT1_BOVIN	Dynein light chain Tctex-type 1	11967380	Subunit organization in cytoplasmic dynein subcomplexes.

Q42577	NDUS7_ARATH	NADH-ubiquinone oxidoreductase 20 kDa subunit, mitochondrial	14671022	Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.

Q03825	MSS11_YEAST	Transcription activator MSS11	12492858	Mss11p is a transcription factor regulating pseudohyphal differentiation, invasive growth and starch metabolism in Saccharomyces cerevisiae in response to nutrient availability.

Q06187	BTK_HUMAN	Tyrosine-protein kinase BTK	9012831	BAP-135, a target for Bruton's tyrosine kinase in response to B cell receptor engagement.

P0AF26	NARJ_ECOLI	Nitrate reductase molybdenum cofactor assembly chaperone NarJ	9305880	Characterization of NarJ, a system-specific chaperone required for nitrate reductase biogenesis in Escherichia coli.

Q24008	INAD_DROME	Inactivation-no-after-potential D protein	11514552	Regulation of Drosophila TRPL channels by immunophilin FKBP59.

Q10714	ACE_DROME	Angiotensin-converting enzyme	12591244	The Drosophila angiotensin-converting enzyme homologue Ance is required for spermiogenesis.

P13645	K1C10_HUMAN	Keratin, type I cytoskeletal 10	2459124	The complete sequence of the human intermediate filament chain keratin 10. Subdomainal divisions and model for folding of end domain sequences.

O14122	CUL4_SCHPO	Cullin-4	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

Q04636	POB3_YEAST	FACT complex subunit POB3	15082784	Structural features of nucleosomes reorganized by yeast FACT and its HMG box component, Nhp6.

P61430	SYCP2_ARATH	Synaptonemal complex protein 2	16230536	The Arabidopsis synaptonemal complex protein ZYP1 is required for chromosome synapsis and normal fidelity of crossing over.

O70536	SOAT1_RAT	Sterol O-acyltransferase 1	9555010	Molecular cloning, functional expression and tissue distribution of rat acyl-coenzyme A:cholesterol acyltransferase.

O17185	SUP9_CAEEL	Two pore potassium channel protein sup-9	14534247	sup-9, sup-10, and unc-93 may encode components of a two-pore K+ channel that coordinates muscle contraction in Caenorhabditis elegans.

Q9H2A9	CHST8_HUMAN	Carbohydrate sulfotransferase 8	10988300	Molecular cloning and expression of the pituitary glycoprotein hormone N-acetylgalactosamine-4-O-sulfotransferase.

Q9JJ48	ZC3H8_MOUSE	Zinc finger CCCH domain-containing protein 8	12077251	Transcriptional regulation of GATA-3 by an intronic regulatory region and fetal liver zinc finger protein 1.

Q96AZ6	ISG20_HUMAN	Interferon-stimulated gene 20 kDa protein	9569007	Expression and estrogen regulation of the HEM45 mRNA in human tumor lines and in the rat uterus.

A1Z9P3	SHRM_DROME	Protein Shroom	16684770	Differential actin-dependent localization modulates the evolutionarily conserved activity of Shroom family proteins.

Q9H4B6	SAV1_HUMAN	Protein salvador homolog 1	16930133	Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled-coil domains, leads to its stabilization and phosphorylation.

P36407	TRI23_RAT	E3 ubiquitin-protein ligase TRIM23	8473324	ARD 1, a 64-kDa guanine nucleotide-binding protein with a carboxyl- terminal ADP-ribosylation factor domain.

P29674	LHX1_XENLA	LIM/homeobox protein Lhx1	12530965	Conserved requirement of Lim1 function for cell movements during gastrulation.

Q96DZ1	ERLEC_HUMAN	Endoplasmic reticulum lectin 1	18502753	Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiP.

P33076	C2TA_HUMAN	MHC class II transactivator	16600381	ZXDC, a novel zinc finger protein that binds CIITA and activates MHC gene transcription.

Q401N2	ZACN_HUMAN	Zinc-activated ligand-gated ion channel	16083862	Cloning and expression of ligand-gated ion-channel receptor L2 in central nervous system.

Q9BYN8	RT26_HUMAN	28S ribosomal protein S26, mitochondrial	11279123	The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present.

O75521	PECI_HUMAN	Peroxisomal 3,2-trans-enoyl-CoA isomerase	11256614	Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.

P13051	UNG_HUMAN	Uracil-DNA glycosylase	9016624	Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene.

Q9HGQ0	YM02_SCHPO	Uncharacterized protein C212.02	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P25627	BUD23_YEAST	Putative methyltransferase BUD23	11452010	A genomic study of the bipolar bud site selection pattern in Saccharomyces cerevisiae.

Q924Y4	GATA2_RAT	Endothelial transcription factor GATA-2	12933836	Effect of transcription factor GATA-2 on phagocytic activity of alveolar macrophages from Pneumocystis carinii-infected hosts.

Q2V4F9	SPXM1_ARATH	SPX domain-containing membrane protein At1g63010	16618929	Mapping the Arabidopsis organelle proteome.

Q9UT95	YL44_SCHPO	Uncharacterized ABC transporter ATP-binding protein C323.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O94652	GLE1_SCHPO	Nucleoporin gle1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NY27	PP4R2_HUMAN	Serine/threonine-protein phosphatase 4 regulatory subunit 2	10769191	A novel 50 kDa protein forms complexes with protein phosphatase 4 and is located at centrosomal microtubule organizing centres.

P49961	ENTP1_HUMAN	Ectonucleoside triphosphate diphosphohydrolase 1	8955160	Identification and characterization of CD39/vascular ATP diphosphohydrolase.

P09208	INSR_DROME	Insulin-like receptor	10455177	The carboxyl terminal extension of the Drosophila insulin receptor homologue binds IRS-1 and influences cell survival.

P84814	OPIP1_AMBTS	Opioid peptide	15752574	An opioid peptide from synganglia of the tick, Amblyomma testindinarium.

Q38997	KIN10_ARATH	SNF1-related protein kinase catalytic subunit alpha KIN10	11387208	SKP1-SnRK protein kinase interactions mediate proteasomal binding of a plant SCF ubiquitin ligase.

P32825	SXA2_SCHPO	Carboxypeptidase sxa2	1549128	Schizosaccharomyces pombe sxa1+ and sxa2+ encode putative proteases involved in the mating response.

Q9VU84	DBNL_DROME	Drebrin-like protein	12975351	Molecular requirements for actin-based lamella formation in Drosophila S2 cells.

P53095	DSD1_YEAST	D-serine dehydratase	17937657	A novel zinc-dependent D-serine dehydratase from Saccharomyces cerevisiae.

P38689	KPR3_YEAST	Ribose-phosphate pyrophosphokinase 3	14562095	Global analysis of protein localization in budding yeast.

Q9NQX6	ZN331_HUMAN	Zinc finger protein 331	10502321	A KRAB zinc finger protein gene is the potential target of 19q13 translocation in benign thyroid tumors.

Q8C4M7	CENPU_MOUSE	Centromere protein U	15116101	cDNA cloning and characterization of a novel gene encoding the MLF1- interacting protein MLF1IP.

Q9QYR9	ACOT2_MOUSE	Acyl-coenzyme A thioesterase 2, mitochondrial	10567408	Peroxisome proliferator-induced long chain acyl-CoA thioesterases comprise a highly conserved novel multi-gene family involved in lipid metabolism.

O94421	SNF22_SCHPO	SWI/SNF chromatin-remodeling complex subunit snf22	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q99JV5	STAR4_MOUSE	StAR-related lipid transfer protein 4	12011453	Crystal structure of the Mus musculus cholesterol-regulated START protein 4 (StarD4) containing a StAR-related lipid transfer domain.

Q9VQH2	DUOX_DROME	Dual oxidase	16272120	A direct role for dual oxidase in Drosophila gut immunity.

P08640	MUC1_YEAST	Flocculation protein FLO11	11027318	A Saccharomyces gene family involved in invasive growth, cell-cell adhesion, and mating.

P40692	MLH1_HUMAN	DNA mismatch repair protein Mlh1	11427529	The interaction of DNA mismatch repair proteins with human exonuclease I.

O15514	RPB4_HUMAN	DNA-directed RNA polymerase II subunit RPB4	9852112	Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.

Q96KC8	DNJC1_HUMAN	DnaJ homolog subfamily C member 1	14668352	The SANT2 domain of the murine tumor cell DnaJ-like protein 1 human homologue interacts with alpha1-antichymotrypsin and kinetically interferes with its serpin inhibitory activity.

Q708S7	ACC2B_DANRE	Amiloride-sensitive cation channel 2-B, neuronal	14970195	A family of acid-sensing ion channels (ASICs) from the zebrafish: widespread e xpression in the central nervous system suggests a conserved role in neuronal communication.

P22599	A1AT2_MOUSE	Alpha-1-antitrypsin 1-2	11961105	Functional diversification during evolution of the murine alpha(1)- proteinase inhibitor family: role of the hypervariable reactive center loop.

Q12186	BBP_YEAST	Branchpoint-bridging protein	10376880	Transient interaction of BBP/ScSF1 and Mud2 with the splicing machinery affects the kinetics of spliceosome assembly.

P39990	SNU13_YEAST	13 kDa ribonucleoprotein-associated protein	11081632	A common core RNP structure shared between the small nucleoar box C/D RNPs and the spliceosomal U4 snRNP.

Q9LZR3	CSLA9_ARATH	Glucomannan 4-beta-mannosyltransferase 9	15647349	Expression of cellulose synthase-like (Csl) genes in insect cells reveals that CslA family members encode mannan synthases.

P53254	UTP22_YEAST	U3 small nucleolar RNA-associated protein 22	15590835	The small-subunit processome is a ribosome assembly intermediate.

P92981	APR2_ARATH	5'-adenylylsulfate reductase 2, chloroplastic	8917599	Three members of a novel small gene-family from Arabidopsis thaliana able to complement functionally an Escherichia coli mutant defective in PAPS reductase activity encode proteins with a thioredoxin-like domain and 'APS reductase' activity.

O88483	PDP1_RAT	[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial	9651365	Isoenzymes of pyruvate dehydrogenase phosphatase. DNA-derived amino acid sequences, expression, and regulation.

Q9LUB6	SNE_ARATH	F-box protein SNE	15161962	The Arabidopsis mutant sleepy1gar2-1 protein promotes plant growth by increasing the affinity of the SCFSLY1 E3 ubiquitin ligase for DELLA protein substrates.

P40848	XRN2_SCHPO	5'-3' exoribonuclease 2	11238999	The dhp1+ gene, encoding a putative nuclear 5'3' exoribonuclease, is required for proper chromosome segregation in fission yeast.

P28221	5HT1D_HUMAN	5-hydroxytryptamine receptor 1D	1565658	Human serotonin 1D receptor is encoded by a subfamily of two distinct genes: 5-HT1D alpha and 5-HT1D beta.

O43791	SPOP_HUMAN	Speckle-type POZ protein	9414087	Identification of a novel nuclear speckle-type protein, SPOP.

Q5VST9	OBSCN_HUMAN	Obscurin	11717165	The complete gene sequence of titin, expression of an unusual ~700 kDa titin isoform and its interaction with obscurin identify a novel Z-line to I-band linking system.

Q06609	RAD51_HUMAN	DNA repair protein RAD51 homolog 1	9396801	A novel nucleic acid-binding protein that interacts with human rad51 recombinase.

Q6UFS5	ZN503_DANRE	Zinc finger protein 503	15042707	nlz gene family is required for hindbrain patterning in the zebrafish.

Q15628	TRADD_HUMAN	Tumor necrosis factor receptor type 1-associated DEATH domain protein	7758105	The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation.

Q8WXE1	ATRIP_HUMAN	ATR-interacting protein	12791985	Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes.

Q86WV1	SKAP1_HUMAN	Src kinase-associated phosphoprotein 1	11909961	SKAP55 coupled with CD45 positively regulates T-cell receptor- mediated gene transcription.

Q8MM24	IDGF1_DROME	Chitinase-like protein Idgf1	9847235	A new family of growth factors produced by the fat body and active on Drosophila imaginal disc cells.

Q12888	TP53B_HUMAN	Tumor suppressor p53-binding protein 1	20347427	Regulation of chromatin architecture by the PWWP domain-containing DNA damage-responsive factor EXPAND1/MUM1.

P48729	KC1A_HUMAN	Casein kinase I isoform alpha	11955436	Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism.

Q9USU3	FBH1_SCHPO	F-box DNA helicase protein 1	16135800	The F-Box DNA helicase Fbh1 prevents Rhp51-dependent recombination without mediator proteins.

Q39134	AAP3_ARATH	Amino acid permease 3	12148530	Low and high affinity amino acid H+-cotransporters for cellular import of neutral and charged amino acids.

P08727	K1C19_HUMAN	Keratin, type I cytoskeletal 19	16000376	Specific interaction of the actin-binding domain of dystrophin with intermediate filaments containing keratin 19.

P79065	TIP1_SCHPO	Tip elongation protein 1	15177031	Tea2p kinesin is involved in spatial microtubule organization by transporting tip1p on microtubules.

Q13347	EIF3I_HUMAN	Eukaryotic translation initiation factor 3 subunit I	17581632	Reconstitution reveals the functional core of mammalian eIF3.

P21957	OPI1_YEAST	Transcriptional repressor OPI1	15455074	Gene recruitment of the activated INO1 locus to the nuclear membrane.

Q8BUV6	LSM11_MOUSE	U7 snRNA-associated Sm-like protein LSm11	19470752	Three proteins of the U7-specific Sm ring function as the molecular ruler to determine the site of 3'-end processing in mammalian histone pre-mRNA.

O60565	GREM1_HUMAN	Gremlin-1	9660951	The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activities.

Q6IA17	SIGIR_HUMAN	Single Ig IL-1-related receptor	15866876	SIGIRR inhibits interleukin-1 receptor- and toll-like receptor 4- mediated signaling through different mechanisms.

P32807	KU70_YEAST	ATP-dependent DNA helicase II subunit 1	12975323	Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends.

P05412	JUN_HUMAN	Transcription factor AP-1	2825349	Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1.

Q16378	PROL4_HUMAN	Proline-rich protein 4	7544782	A major human lacrimal gland mRNA encodes a new proline-rich protein family member.

O74401	ERO11_SCHPO	ERO1-like protein 1	15449306	Schizosaccharomyces pombe ER oxidoreductin-like proteins SpEro1a p and SpEro1b p.

P61201	CSN2_HUMAN	COP9 signalosome complex subunit 2	9535219	A novel protein complex involved in signal transduction possessing similarities to 26S proteasome subunits.

P38088	SYG_YEAST	Glycyl-tRNA synthetase 1	10874035	One of two genes encoding glycyl-tRNA synthetase in Saccharomyces cerevisiae provides mitochondrial and cytoplasmic functions.

P33205	FXA4A_XENLA	Forkhead box protein A4-A	7789266	Patterning of the mesoderm in Xenopus: dose-dependent and synergistic effects of Brachyury and Pintallavis.

Q9FKZ3	LBD36_ARATH	LOB domain-containing protein 36	15821980	ASYMMETRIC LEAVES2-LIKE1 gene, a member of the AS2/LOB family, controls proximal-distal patterning in Arabidopsis petals.

P53860	PDR16_YEAST	Phosphatidylinositol transfer protein PDR16	12869188	Subcellular localization of yeast Sec14 homologues and their involvement in regulation of phospholipid turnover.

Q04827	CCND2_RAT	G1/S-specific cyclin-D2	7926809	Induction of D2 and D3 cyclin-encoding genes during promotion of the G1/S transition by prolactin in rat Nb2 cells.

Q99N13	HDAC9_MOUSE	Histone deacetylase 9	11022042	Association of COOH-terminal-binding protein (CtBP) and MEF2- interacting transcription repressor (MITR) contributes to transcriptional repression of the MEF2 transcription factor.

Q9Z209	LAYN_CRIGR	Layilin	9786953	Layilin, a novel talin-binding transmembrane protein homologous with C-type lectins, is localized in membrane ruffles.

Q2UY11	COSA1_MOUSE	Collagen alpha-1(XXVIII) chain	16330543	Collagen XXVIII, a novel von Willebrand factor A domain-containing protein with many imperfections in the collagenous domain.

P0A9P0	DLDH_ECOLI	Dihydrolipoyl dehydrogenase	2211531	The lpd gene product functions as the L protein in the Escherichia coli glycine cleavage enzyme system.

P21926	CD9_HUMAN	CD9 antigen	2037603	cDNA cloning and expression of platelet p24/CD9. Evidence for a new family of multiple membrane-spanning proteins.

P38336	POP4_YEAST	RNases MRP/P 32.9 kDa subunit	9085845	A novel protein shared by RNase MRP and RNase P.

Q9NAN2	PAR6_CAEEL	Partitioning defective protein 6	8898226	par-6, a gene involved in the establishment of asymmetry in early C. elegans embryos, mediates the asymmetric localization of PAR-3.

P55072	TERA_HUMAN	Transitional endoplasmic reticulum ATPase	17525332	ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

P01094	IPA3_YEAST	Protease A inhibitor 3	2037077	The proteinase yscA-inhibitor, IA3, gene. Studies of cytoplasmic proteinase inhibitor deficiency on yeast physiology.

O43555	GON2_HUMAN	Progonadoliberin-2	9419371	Second gene for gonadotropin-releasing hormone in humans.

P53088	CTU1_YEAST	Cytoplasmic tRNA 2-thiolation protein 1	18755837	A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae.

O43294	TGFI1_HUMAN	Transforming growth factor beta-1-induced transcript 1 protein	10075738	Cloning and characterization of androgen receptor coactivator, ARA55, in human prostate.

Q12522	IF6_YEAST	Eukaryotic translation initiation factor 6	9891075	The Saccharomyces cerevisiae homologue of mammalian translation initiation factor 6 does not function as a translation initiation factor.

O14135	SET8_SCHPO	SET domain-containing protein 8	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q5YGP7	PLET2_ARATH	AP2-like ethylene-responsive transcription factor PLT2	15454085	The PLETHORA genes mediate patterning of the Arabidopsis root stem cell niche.

Q8W234	SEUSS_ARATH	Transcriptional corepressor SEUSS	15277686	Transcriptional repression of target genes by LEUNIG and SEUSS, two interacting regulatory proteins for Arabidopsis flower development.

Q12102	CFT2_YEAST	Cleavage factor two protein 2	9099738	Cleavage factor II of Saccharomyces cerevisiae contains homologues to subunits of the mammalian Cleavage/ polyadenylation specificity factor and exhibits sequence-specific, ATP-dependent interaction with precursor RNA.

P42526	HATB_DICDI	Hisactophilin-2	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q8BJ37	TYDP1_MOUSE	Tyrosyl-DNA phosphodiesterase 1	17914460	TDP1 facilitates chromosomal single-strand break repair in neurons and is neuroprotective in vivo.

O43448	KCAB3_HUMAN	Voltage-gated potassium channel subunit beta-3	9857044	Coexpression of the KCNA3B gene product with Kv1.5 leads to a novel A-type potassium channel.

O88509	DNM3B_MOUSE	DNA (cytosine-5)-methyltransferase 3B	16085498	The PHD finger/bromodomain of NoRC interacts with acetylated histone H4K16 and is sufficient for rDNA silencing.

P49018	GPI8_YEAST	GPI-anchor transamidase	11598210	The GPI transamidase complex of Saccharomyces cerevisiae contains Gaa1p, Gpi8p, and Gpi16p.

Q65YR7	CYTA2_DICDI	Cystatin-A2	15255188	Identification of cysteine protease inhibitors that belong to cystatin family 1 in the cellular slime mold Dictyostelium discoideum.

Q9NZJ4	SACS_HUMAN	Sacsin	19208651	The ataxia protein sacsin is a functional co-chaperone that protects against polyglutamine-expanded ataxin-1.

P32567	SMP2_YEAST	Protein SMP2	8437575	A gene, SMP2, involved in plasmid maintenance and respiration in Saccharomyces cerevisiae encodes a highly charged protein.

Q12134	HUA2_YEAST	Protein HUA2	14562095	Global analysis of protein localization in budding yeast.

P24100	CDKA1_ARATH	Cyclin-dependent kinase A-1	11096103	The Arabidopsis D-type cyclins CycD2 and CycD3 both interact in vivo with the PSTAIRE cyclin-dependent kinase Cdc2a but are differentially controlled.

O14561	ACPM_HUMAN	Acyl carrier protein, mitochondrial	9878551	cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed.

P43556	RGD2_YEAST	Rho-GTPase-activating protein RGD2	11591390	Functional characterization of the Bag7, Lrg1 and Rgd2 RhoGAP proteins from Saccharomyces cerevisiae.

P70218	M4K1_MOUSE	Mitogen-activated protein kinase kinase kinase kinase 1	9003777	HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway.

P18117	THBA_XENLA	Thyroid hormone receptor beta-A	16627555	In vitro and in vivo analysis of the thyroid system-disrupting activities of brominated phenolic and phenol compounds in Xenopus laevis.

O74423	ENT1_SCHPO	Epsin-1	15659877	Fission yeast epsin, Ent1p is required for endocytosis and involved in actin organization.

Q9HFF4	PPK1_SCHPO	Serine/threonine-protein kinase ppk1	15821139	Systematic deletion analysis of fission yeast protein kinases.

Q8R500	MFN2_RAT	Mitofusin-2	15322553	Dysregulation of HSG triggers vascular proliferative disorders.

Q19157	PIN2_CAEEL	LIM domain-containing protein pin-2	9885243	A conserved LIM protein that affects muscular adherens junction integrity and mechanosensory function in Caenorhabditis elegans.

O15392	BIRC5_HUMAN	Baculoviral IAP repeat-containing protein 5	10949039	Crystal structure of human survivin reveals a bow tie-shaped dimer with two unusual alpha-helical extensions.

Q9YHZ6	CDC45_XENLA	Cell division control protein 45 homolog	12743046	Xenopus Cut5 is essential for a CDK-dependent process in the initiation of DNA replication.

Q9FM64	PP431_ARATH	Pentatricopeptide repeat-containing protein At5g55740, chloroplastic	17483454	Conserved domain structure of pentatricopeptide repeat proteins involved in chloroplast RNA editing.

Q9FIZ3	GSO2_ARATH	LRR receptor-like serine/threonine-protein kinase GSO2	15634699	Genetic and molecular identification of genes required for female gametophyte development and function in Arabidopsis.

Q99LW6	YAF2_MOUSE	YY1-associated factor 2	14557078	The mouse YAF2 gene generates two distinct transcripts and is expressed in pre- and postimplantation embryos.

Q5HYA8	MKS3_HUMAN	Meckelin	19815549	Meckel-Gruber syndrome protein MKS3 is required for endoplasmic reticulum-associated degradation of surfactant protein C.

Q15543	TAF13_HUMAN	Transcription initiation factor TFIID subunit 13	7729427	Cloning and characterization of hTAFII18, hTAFII20 and hTAFII28: three subunits of the human transcription factor TFIID.

O60487	MPZL2_HUMAN	Myelin protein zero-like protein 2	9585423	Epithelial V-like antigen (EVA), a novel member of the immunoglobulin superfamily, expressed in embryonic epithelia with a potential role as homotypic adhesion molecule in thymus histogenesis.

P40554	URM1_YEAST	Ubiquitin-related modifier 1	19145231	Ubiquitin-related modifier Urm1 acts as a sulphur carrier in thiolation of eukaryotic transfer RNA.

P28234	CXA5_RAT	Gap junction alpha-5 protein	1328644	Molecular cloning and expression of rat connexin40, a gap junction protein expressed in vascular smooth muscle.

O96017	CHK2_HUMAN	Serine/threonine-protein kinase Chk2	9836640	Linkage of ATM to cell cycle regulation by the Chk2 protein kinase.

Q9P1T7	MDFIC_HUMAN	MyoD family inhibitor domain-containing protein	12944466	The human I-mfa domain-containing protein, HIC, interacts with cyclin T1 and modulates P-TEFb-dependent transcription.

Q96J02	ITCH_HUMAN	E3 ubiquitin-protein ligase Itchy homolog	18628966	AIP4/Itch regulates Notch receptor degradation in the absence of ligand.

O74319	TAF73_SCHPO	Transcription initiation factor TFIID subunit taf73	11279037	Two WD repeat-containing TATA-binding protein-associated factors in fission yeast that suppress defects in the anaphase-promoting complex.

P0A9E9	NSR_ECOLI	Regulatory protein nsr	11101674	YeiL, the third member of the CRP-FNR family in Escherichia coli.

Q09864	HSP60_SCHPO	Heat shock protein 60, mitochondrial	8566770	Cloning and characterization of the mitochondrial HSP60-encoding gene of Schizosaccharomyces pombe.

P18916	ACHG_RAT	Acetylcholine receptor subunit gamma	1702709	Primary structure and functional expression of the alpha-, beta-, gamma-, delta- and epsilon-subunits of the acetylcholine receptor from rat muscle.

P04625	THA_CHICK	Thyroid hormone receptor alpha	11259580	PSF is a novel corepressor that mediates its effect through Sin3A and the DNA binding domain of nuclear hormone receptors.

Q9Y5T5	UBP16_HUMAN	Ubiquitin carboxyl-terminal hydrolase 16	17914355	Regulation of cell cycle progression and gene expression by H2A deubiquitination.

O88279	SLIT1_RAT	Slit homolog 1 protein	11754167	Spatiotemporal expression patterns of slit and robo genes in the rat brain.

P22516	CHL1_YEAST	ATP-dependent RNA helicase CHL1	14742714	Identification of protein complexes required for efficient sister chromatid cohesion.

Q64294	PDPN_RAT	Podoplanin	7851650	Cloning, characterization, and development expression of a rat lung alveolar type I cell gene in embryonic endodermal and neural derivatives.

Q9QXQ0	ACTN4_RAT	Alpha-actinin-4	15505042	Pdlim2, a novel PDZ-LIM domain protein, interacts with alpha-actinins and filamin A.

Q8R5H1	UBP15_MOUSE	Ubiquitin carboxyl-terminal hydrolase 15	12532266	Isolation and characterization of the mouse ubiquitin-specific protease Usp15.

Q6NVY1	HIBCH_HUMAN	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial	8824301	Primary structure and tissue-specific expression of human beta- hydroxyisobutyryl-coenzyme A hydrolase.

Q58576	PAN_METJA	Proteasome-activating nucleotidase	19481527	Structural insights into the regulatory particle of the proteasome from Methanocaldococcus jannaschii.

P41241	CSK_MOUSE	Tyrosine-protein kinase CSK	12612075	Phosphorylation-dependent regulation of T-cell activation by PAG/Cbp, a lipid raft-associated transmembrane adaptor.

Q03305	RMT2_YEAST	Arginine N-methyltransferase 2	11856739	Yeast ribosomal protein L12 is a substrate of protein-arginine methyltransferase 2.

P70425	RIT2_MOUSE	GTP-binding protein Rit2	10545207	Biochemical characterization of the Ras-related GTPases Rit and Rin.

Q99729	ROAA_HUMAN	Heterogeneous nuclear ribonucleoprotein A/B	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

Q12816	TROP_HUMAN	Trophinin	7758945	Trophinin and tastin, a novel cell adhesion molecule complex with potential involvement in embryo implantation.

Q8CBC4	CNST_MOUSE	Consortin	19864490	Consortin, a trans-Golgi network cargo receptor for the plasma membrane targeting and recycling of connexins.

Q14093	CYLC2_HUMAN	Cylicin-2	7737358	The protein complexity of the cytoskeleton of bovine and human sperm heads: the identification and characterization of cylicin II.

Q02870	ERCC3_DROME	DNA excision repair protein haywire	1458540	A Drosophila model for Xeroderma pigmentosum and Cockayne's syndrome: haywire encodes the fly homolog of ERCC3, a human excision repair gene.

Q9VH38	TFB2M_DROME	Dimethyladenosine transferase 2, mitochondrial	15060065	Drosophila mitochondrial transcription factor B2 regulates mitochondrial DNA copy number and transcription in schneider cells.

Q9NY25	CLC5A_HUMAN	C-type lectin domain family 5 member A	10449773	Myeloid DAP12-associating lectin (MDL)-1 is a cell surface receptor involved in the activation of myeloid cells.

P42753	CCD31_ARATH	Cyclin-D3-1	11123807	Promotive effect of brassinosteroids on cell division involves a distinct CycD3-induction pathway in Arabidopsis.

Q9TW65	DMD_CAEEL	Dystrophin-1	9933302	Mutations in the Caenorhabditis elegans dystrophin-like gene dys-1 lead to hyperactivity and suggest a link with cholinergic transmission.

Q62728	PTN21_RAT	Tyrosine-protein phosphatase non-receptor type 21	7805871	Identification of a novel protein tyrosine phosphatase with sequence homology to the cytoskeletal proteins of the band 4.1 family.

P09836	UHPC_ECOLI	Regulatory protein uhpC	1569007	Structure and function of the uhp genes for the sugar phosphate transport system in Escherichia coli and Salmonella typhimurium.

Q54R41	GPA9_DICDI	Guanine nucleotide-binding protein alpha-9 subunit	12176329	Galpha-mediated inhibition of developmental signal response.

P38818	CTM1_YEAST	Cytochrome c lysine N-methyltransferase 1	10791961	Cytochrome c methyltransferase, Ctm1p, of yeast.

Q64249	NR6A1_MOUSE	Nuclear receptor subfamily 6 group A member 1	9025060	xGCNF, a nuclear orphan receptor is expressed during neurulation in Xenopus laevis.

P32908	SMC1_YEAST	Structural maintenance of chromosomes protein 1	9990856	Yeast cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication.

P53894	CBK1_YEAST	Serine/threonine-protein kinase CBK1	11854408	Pag1p, a novel protein associated with protein kinase Cbk1p, is required for cell morphogenesis and proliferation in Saccharomyces cerevisiae.

P85055	ES2SE_RANSV	Esculentin-2SE	16386333	Histamine-releasing and antimicrobial peptides from the skin secretions of the dusky gopher frog, Rana sevosa.

Q9Y7L8	RSSA1_SCHPO	40S ribosomal protein S0-A	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9WTX6	CUL1_MOUSE	Cullin-1	16880526	Fbxw8 is essential for Cul1-Cul7 complex formation and for placental development.

Q9WTU3	SCN8A_MOUSE	Sodium channel protein type 8 subunit alpha	9828131	Exon organization, coding sequence, physical mapping, and polymorphic intragenic markers for the human neuronal sodium channel gene SCN8A.

Q00959	NMDE1_RAT	Glutamate [NMDA] receptor subunit epsilon-1	7569905	Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95.

P63208	SKP1_HUMAN	S-phase kinase-associated protein 1	20181953	Structural basis of dimerization-dependent ubiquitination by the SCF(Fbx4) ubiquitin ligase.

Q91ZP3	LPIN1_MOUSE	Phosphatidate phosphatase LPIN1	19753306	Sumoylation regulates nuclear localization of lipin-1alpha in neuronal cells.

Q9QXX8	NUFP1_MOUSE	Nuclear fragile X mental retardation-interacting protein 1	10556305	A novel RNA-binding nuclear protein that interacts with the fragile X mental retardation (FMR1) protein.

Q22472	RIC3_CAEEL	Resistance to inhibitors of cholinesterase protein 3	11867529	The C. elegans ric-3 gene is required for maturation of nicotinic acetylcholine receptors.

Q3E840	DPH3_YEAST	Diphthamide biosynthesis protein 3	14562095	Global analysis of protein localization in budding yeast.

P36054	RCN1_YEAST	Calcipressin-like protein	10887154	A conserved family of calcineurin regulators.

Q9SCZ4	FERON_ARATH	Receptor-like protein kinase FERONIA	17644812	A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome.

Q9HAN9	NMNA1_HUMAN	Nicotinamide mononucleotide adenylyltransferase 1	11248244	Characterization of recombinant human nicotinamide mononucleotide adenylyl transferase (NMNAT), a nuclear enzyme essential for NAD synthesis.

P17764	THIL_RAT	Acetyl-CoA acetyltransferase, mitochondrial	2478525	Molecular cloning and nucleotide sequence of cDNA encoding the entire precursor of rat mitochondrial acetoacetyl-CoA thiolase.

Q13907	IDI1_HUMAN	Isopentenyl-diphosphate Delta-isomerase 1	8020941	A human promyelocyte mRNA transiently induced by TPA is homologous to yeast IPP isomerase.

Q91XM9	DLG2_MOUSE	Disks large homolog 2	12890763	Impaired NMDA receptor-mediated postsynaptic function and blunted NMDA receptor-dependent persistent pain in mice lacking postsynaptic density-93 protein.

Q9UST6	SPC24_SCHPO	Kinetochore protein spc24	15728720	Dissociation of the Nuf2-Ndc80 complex releases centromeres from the spindle-pole body during meiotic prophase in fission yeast.

Q3LRZ3	AXLP1_CAEEL	Axin-like protein 1	17601533	Two functionally distinct axin-like proteins regulate canonical Wnt signaling in C. elegans.

Q5VRR0	IAA20_ORYSJ	Auxin-responsive protein IAA20	16200395	Structure and expression analysis of early auxin-responsive Aux/IAA gene family in rice (Oryza sativa).

Q9Y263	PLAP_HUMAN	Phospholipase A-2-activating protein	9931468	Molecular characterization of cDNA for phospholipase A2-activating protein.

P37287	PIGA_HUMAN	Phosphatidylinositol N-acetylglucosaminyltransferase subunit A	16162815	The initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-Y, a seventh component.

P62820	RAB1A_HUMAN	Ras-related protein Rab-1A	2501306	The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion.

Q96RU8	TRIB1_HUMAN	Tribbles homolog 1	15299019	Human tribbles, a protein family controlling mitogen-activated protein kinase cascades.

P93194	RPK1_IPONI	Receptor-like protein kinase	10949373	Alternative transcript initiation and novel post-transcriptional processing of a leucine-rich repeat receptor-like protein kinase gene that responds to short-day photoperiodic floral induction in morning glory (Ipomoea nil).

P43219	GIPR_RAT	Gastric inhibitory polypeptide receptor	8243312	Gastric inhibitory polypeptide receptor, a member of the secretin- vasoactive intestinal peptide receptor family, is widely distributed in peripheral organs and the brain.

Q80YD6	SRGEF_MOUSE	Secretion-regulating guanine nucleotide exchange factor	10571079	DelGEF, an RCC1-related protein encoded by a gene on chromosome 11p14 critical for two forms of hereditary deafness.

Q9UHC1	MLH3_HUMAN	DNA mismatch repair protein Mlh3	10615123	MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instability.

O59802	GPI2_SCHPO	Phosphatidylinositol N-acetylglucosaminyltransferase GPI2 subunit	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q17607	MCE1_CAEEL	mRNA-capping enzyme	9200605	An RNA 5'-triphosphatase related to the protein tyrosine phosphatases.

O13665	FAR11_SCHPO	Factor arrest protein 11	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P78364	PHC1_HUMAN	Polyhomeotic-like protein 1	9121482	Identification and characterization of interactions between the vertebrate polycomb-group protein BMI1 and human homologs of polyhomeotic.

Q92560	BAP1_HUMAN	Ubiquitin carboxyl-terminal hydrolase BAP1	18757409	BRCA1-associated protein-1 is a tumor suppressor that requires deubiquitinating activity and nuclear localization.

P53350	PLK1_HUMAN	Serine/threonine-protein kinase PLK1	16439210	The evi5 oncogene regulates cyclin accumulation by stabilizing the anaphase-promoting complex inhibitor emi1.

Q14849	STAR3_HUMAN	StAR-related lipid transfer protein 3	7490069	Identification of four novel human genes amplified and overexpressed in breast carcinoma and localized to the q11-q21.3 region of chromosome 17.

Q1ZXQ8	MTAA_DICDI	Centrosomal protein 224	14517319	Regulated expression of the centrosomal protein DdCP224 affects microtubule dynamics and reveals mechanisms for the control of supernumerary centrosome number.

Q62902	LMAN1_RAT	Protein ERGIC-53	8626736	Molecular cloning and expression of a 58-kDa cis-Golgi and intermediate compartment protein.

Q9ER31	ENTP6_RAT	Ectonucleoside triphosphate diphosphohydrolase 6	11042118	Sequencing, functional expression and characterization of rat NTPDase6, a nucleoside diphosphatase and novel member of the ecto- nucleoside triphosphate diphosphohydrolase family.

Q9NVR2	INT10_HUMAN	Integrator complex subunit 10	16239144	Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.

Q92935	EXTL1_HUMAN	Exostosin-like 1	9037597	Identification and localization of the gene for EXTL, a third member of the multiple exostoses gene family.

Q949P1	ABAH1_ARATH	Abscisic acid 8'-hydroxylase 1	17010113	Regulation of hormone metabolism in Arabidopsis seeds: phytochrome regulation of abscisic acid metabolism and abscisic acid regulation of gibberellin metabolism.

Q04462	SYVC_RAT	Valyl-tRNA synthetase	8428657	Cloning, sequencing and expression of a cDNA encoding mammalian valyl-tRNA synthetase.

P87312	CLF1_SCHPO	Pre-mRNA-splicing factor clf1	10409726	Myb-related fission yeast cdc5p is a component of a 40S snRNP- containing complex and is essential for pre-mRNA splicing.

Q05521	DPP1_YEAST	Diacylglycerol pyrophosphate phosphatase 1	11139591	Regulation of the Saccharomyces cerevisiae DPP1-encoded diacylglycerol pyrophosphate phosphatase by zinc.

O75752	B3GL1_HUMAN	UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1	9582303	A family of human beta3-galactosyltransferases. Characterization of four members of a UDP-galactose:beta-N-acetyl-glucosamine/beta- nacetyl-galactosamine beta-1,3-galactosyltransferase family.

Q9NYL2	MLTK_HUMAN	Mitogen-activated protein kinase kinase kinase MLT	15342622	The stress kinase MRK contributes to regulation of DNA damage checkpoints through a p38gamma-independent pathway.

P32318	THI4_YEAST	Thiazole biosynthetic enzyme, mitochondrial	9367751	Dual role for the yeast THI4 gene in thiamine biosynthesis and DNA damage tolerance.

P78552	I13R1_HUMAN	Interleukin-13 receptor subunit alpha-1	18243101	Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system.

P07281	RS19B_YEAST	40S ribosomal protein S19-B	6814480	Isolation of seventeen proteins and amino-terminal amino acid sequences of eight proteins from cytoplasmic ribosomes of yeast.

Q15796	SMAD2_HUMAN	Mothers against decapentaplegic homolog 2	19049980	SKI and MEL1 cooperate to inhibit transforming growth factor-beta signal in gastric cancer cells.

Q03358	MSX2_MOUSE	Homeobox protein MSX-2	15383550	Bone morphogenetic protein-2-induced alkaline phosphatase expression is stimulated by Dlx5 and repressed by Msx2.

Q63707	PYRD_RAT	Dihydroorotate dehydrogenase, mitochondrial	7660999	Molecular cloning and sequence analyses of rat liver dihydroorotate dehydrogenase.

P25490	TYY1_HUMAN	Transcriptional repressor protein YY1	1655281	Transcriptional repression by YY1, a human GLI-Kruppel-related protein, and relief of repression by adenovirus E1A protein.

Q9VVR6	SGF11_DROME	SAGA-associated factor 11 homolog	18188155	SAGA-mediated H2B deubiquitination controls the development of neuronal connectivity in the Drosophila visual system.

Q8IUX4	ABC3F_HUMAN	DNA dC->dU-editing enzyme APOBEC-3F	11863358	An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22.

P32641	RAD24_YEAST	Checkpoint protein RAD24	12665596	Mechanical link between cohesion establishment and DNA replication: Ctf7p/Eco1p, a cohesion establishment factor, associates with three different replication factor C complexes.

P0A9V1	LPTB_ECOLI	Lipopolysaccharide export system ATP-binding protein lptB	16079137	Protein complexes of the Escherichia coli cell envelope.

Q9XIE6	ALA3_ARATH	Phospholipid-transporting ATPase 3	18344284	The Arabidopsis P4-ATPase ALA3 localizes to the golgi and requires a beta-subunit to function in lipid translocation and secretory vesicle formation.

Q64311	NTAN1_MOUSE	Protein N-terminal asparagine amidohydrolase	8910481	A mouse amidase specific for N-terminal asparagine. The gene, the enzyme, and their function in the N-end rule pathway.

Q62132	PTPRR_MOUSE	Receptor-type tyrosine-protein phosphatase R	10601328	A novel regulatory mechanism of MAP kinases activation and nuclear translocation mediated by PKA and the PTP-SL tyrosine phosphatase.

Q921E6	EED_MOUSE	Polycomb protein EED	12627233	Genome imprinting regulated by the mouse Polycomb group protein Eed.

P43166	CAH7_HUMAN	Carbonic anhydrase 7	1783392	Characterization of the human gene for a newly discovered carbonic anhydrase, CA VII, and its localization to chromosome 16.

Q92576	PHF3_HUMAN	PHD finger protein 3	11856869	PHF3 expression is frequently reduced in glioma.

P11488	GNAT1_HUMAN	Guanine nucleotide-binding protein G(t) subunit alpha-1	2534964	Alpha transducin is present in blue-, green-, and red-sensitive cone photoreceptors in the human retina.

P40792	RAC1_DROME	Ras-related protein Rac1	12818175	CYFIP/Sra-1 controls neuronal connectivity in Drosophila and links the Rac1 GTPase pathway to the fragile X protein.

P42356	PI4KA_HUMAN	Phosphatidylinositol 4-kinase alpha	7961848	Cloning and characterization of a human phosphatidylinositol 4- kinase.

P84708	CAI_PHAVU	Chitinolytic alpha-amylase inhibitor PvCAI	16213488	Identification of a novel bean alpha-amylase inhibitor with chitinolytic activity.

Q9NZ43	USE1_HUMAN	Vesicle transport protein USE1	15029241	Implication of ZW10 in membrane trafficking between the endoplasmic reticulum and Golgi.

P0AF36	ZAPB_ECOLI	Cell division protein zapB	18394147	Novel coiled-coil cell division factor ZapB stimulates Z ring assembly and cell division.

Q00872	MYPC1_HUMAN	Myosin-binding protein C, slow-type	8375400	Complete sequence of human fast-type and slow-type muscle myosin- binding-protein C (MyBP-C). Differential expression, conserved domain structure and chromosome assignment.

O75410	TACC1_HUMAN	Transforming acidic coiled-coil-containing protein 1	15064709	Aurora B -TACC1 protein complex in cytokinesis.

P06731	CEAM5_HUMAN	Carcinoembryonic antigen-related cell adhesion molecule 5	3814146	Primary structure of human carcinoembryonic antigen (CEA) deduced from cDNA sequence.

Q9P7D5	YOFE_SCHPO	Uncharacterized protein P4H10.14c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P05109	S10A8_HUMAN	Protein S100-A8	3313057	Two calcium-binding proteins in infiltrate macrophages of rheumatoid arthritis.

Q95ZG4	SPC98_DICDI	Spindle pole body component 98	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

Q9BY67	CADM1_HUMAN	Cell adhesion molecule 1	15811952	The tumor suppressor TSLC1/NECL-2 triggers NK-cell and CD8+ T-cell responses through the cell-surface receptor CRTAM.

Q9QX98	PTF1A_MOUSE	Pancreas transcription factor 1 subunit alpha	9851981	The bHLH protein PTF1-p48 protein is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas.

P87227	MIS6_SCHPO	Inner centromere protein mis6	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q96CW1	AP2M1_HUMAN	AP-2 complex subunit mu	12032142	Subunit H of the V-ATPase binds to the medium chain of adaptor protein complex 2 and connects Nef to the endocytic machinery.

Q9UBV7	B4GT7_HUMAN	Beta-1,4-galactosyltransferase 7	10473568	Cloning and expression of a proteoglycan UDP-galactose:beta-xylose beta1,4-galactosyltransferase I. A seventh member of the human beta4- galactosyltransferase gene family.

Q04409	EMI2_YEAST	Putative glucokinase-2	14562095	Global analysis of protein localization in budding yeast.

O54949	NLK_MOUSE	Serine/threonine-protein kinase NLK	17785444	Nemo-like kinase-myocyte enhancer factor 2A signaling regulates anterior formation in Xenopus development.

P33240	CSTF2_HUMAN	Cleavage stimulation factor subunit 2	1741396	The human 64-kDa polyadenylylation factor contains a ribonucleoprotein-type RNA binding domain and unusual auxiliary motifs.

P59889	S39A1_DANRE	Zinc transporter ZIP1	15683366	Molecular cloning and functional characterization of a high-affinity zinc importer (DrZIP1) from zebrafish (Danio rerio).

P12003	VINC_CHICK	Vinculin	10320340	Molecular interactions of N-RAP, a nebulin-related protein of striated muscle myotendon junctions and intercalated disks.

P27900	GL1_ARATH	Trichome differentiation protein GL1	15361138	Comprehensive identification of Arabidopsis thaliana MYB transcription factors interacting with R/B-like BHLH proteins.

Q9VWF2	SAYP_DROME	Supporter of activation of yellow protein	15616585	A novel multidomain transcription coactivator SAYP can also repress transcription in heterochromatin.

Q5FBB7	SGOL1_HUMAN	Shugoshin-like 1	18331714	sSgo1, a major splice variant of Sgo1, functions in centriole cohesion where it is regulated by Plk1.

Q07955	SRSF1_HUMAN	Serine/arginine-rich splicing factor 1	1830244	Functional expression of cloned human splicing factor SF2: homology to RNA-binding proteins, U1 70K, and Drosophila splicing regulators.

P01555	CHTA_VIBCH	Cholera enterotoxin subunit A	6646234	Cholera toxin genes: nucleotide sequence, deletion analysis and vaccine development.

Q12983	BNIP3_HUMAN	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3	9396766	The E1B 19K/Bcl-2-binding protein Nip3 is a dimeric mitochondrial protein that activates apoptosis.

P37238	PPARG_MOUSE	Peroxisome proliferator-activated receptor gamma	15687259	Hic-5 regulates an epithelial program mediated by PPARgamma.

Q6ZN17	LN28B_HUMAN	Protein lin-28 homolog B	19703396	TUT4 in concert with Lin28 suppresses MicroRNA biogenesis through pre-microRNA uridylation.

Q9D9T8	EFHC1_MOUSE	EF-hand domain-containing protein 1	15258581	Mutations in EFHC1 cause juvenile myoclonic epilepsy.

P23415	GLRA1_HUMAN	Glycine receptor subunit alpha-1	15952785	Structure and dynamics of the second and third transmembrane domains of human glycine receptor.

P43609	RSC8_YEAST	Chromatin structure-remodeling complex protein RSC8	8980231	RSC, an essential, abundant chromatin-remodeling complex.

Q8T137	GSHR_DICDI	Glutathione reductase	16678813	Reduced glutathione levels affect the culmination and cell fate decision in Dictyostelium discoideum.

P62140	PP1B_HUMAN	Serine/threonine-protein phosphatase PP1-beta catalytic subunit	19377461	GlcNAcylation of a histone methyltransferase in retinoic-acid-induced granulopoiesis.

Q00729	H2B1A_RAT	Histone H2B type 1-A	3666307	Molecular cloning and differential expression of somatic and testis- specific H2B histone genes during rat spermatogenesis.

Q01815	CAC1C_MOUSE	Voltage-dependent L-type calcium channel subunit alpha-1C	1385406	Expression of a cDNA for a neuronal calcium channel alpha1 subunit enhances secretion from adrenal chromaffin cells.

Q94JU3	CSN7_ARATH	COP9 signalosome complex subunit 7	11029466	Arabidopsis eIF3e (INT-6) associates with both eIF3c and the COP9 signalosome subunit CSN7.

P61163	ACTZ_HUMAN	Alpha-centractin	7696711	Beta-centractin: characterization and distribution of a new member of the centractin family of actin-related proteins.

P40818	UBP8_HUMAN	Ubiquitin carboxyl-terminal hydrolase 8	17711858	The MIT domain of UBPY constitutes a CHMP binding and endosomal localization signal required for efficient epidermal growth factor receptor degradation.

Q03167	TGBR3_HUMAN	Transforming growth factor beta receptor type 3	1333192	Molecular cloning and characterization of the human and porcine transforming growth factor-beta type III receptors.

Q9VF87	CYFIP_DROME	Cytoplasmic FMR1-interacting protein	15385157	WAVE/SCAR, a multifunctional complex coordinating different aspects of neuronal connectivity.

O60939	SCN2B_HUMAN	Sodium channel subunit beta-2	9295116	Structure and chromosomal localization of the beta2 subunit of the human brain sodium channel.

P0AFE4	NUOK_ECOLI	NADH-quinone oxidoreductase subunit K	15919996	Global topology analysis of the Escherichia coli inner membrane proteome.

Q91XS8	ST17B_RAT	Serine/threonine-protein kinase 17B	11481038	A serine/threonine kinase which causes apoptosis-like cell death interacts with a calcineurin B-like protein capable of binding Na+/H+ exchanger.

Q9UEW8	STK39_HUMAN	STE20/SPS1-related proline-alanine-rich protein kinase	10980603	SPAK, a STE20/SPS1-related kinase that activates the p38 pathway.

Q9P3U2	YKX4_SCHPO	Uncharacterized AAA domain-containing protein C328.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q3E9A0	ANTR6_ARATH	Probable anion transporter 6, chloroplastic	18086223	Functional analysis of the Arabidopsis PHT4 family of intracellular phosphate transporters.

O94478	MU137_SCHPO	Meiotically up-regulated gene 137 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q61206	PA1B2_MOUSE	Platelet-activating factor acetylhydrolase IB subunit beta	8954729	Platelet-activating factor acetylhydrolase expression and activity suggest a link between neuronal migration and platelet-activating factor.

O43050	ERG26_SCHPO	Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q8R5I7	MYCD_RAT	Myocardin	12756293	Myocardin is a master regulator of smooth muscle gene expression.

Q9NRW7	VPS45_HUMAN	Vacuolar protein sorting-associated protein 45	10404641	Molecular cloning and characterization of a cDNA encoding the human leucocyte vacuolar protein sorting (hlVps45).

Q9XW10	PAD1_CAEEL	Protein pad-1	10950924	C21orf5, a novel human chromosome 21 gene, has a Caenorhabditis elegans ortholog (pad-1) required for embryonic patterning.

Q13018	PLA2R_HUMAN	Secretory phospholipase A2 receptor	7721806	The human 180-kDa receptor for secretory phospholipases A2. Molecular cloning, identification of a secreted soluble form, expression, and chromosomal localization.

Q925F2	ESAM_MOUSE	Endothelial cell-selective adhesion molecule	11279107	Cloning of an immunoglobulin family adhesion molecule selectively expressed by endothelial cells.

Q5SNZ0	GRDN_MOUSE	Girdin	15882442	A novel hook-related protein family and the characterization of hook- related protein 1.

Q07800	PSR1_YEAST	Phosphatase PSR1	10777497	Psr1p/Psr2p, two plasma membrane phosphatases with an essential DXDX(T/V) motif required for sodium stress response in yeast.

Q04177	UTP5_YEAST	U3 small nucleolar RNA-associated protein 5	15489292	RNA polymerase I transcription and pre-rRNA processing are linked by specific SSU processome components.

Q54UF7	LDHD_DICDI	Putative D-lactate dehydrogenase	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q62730	DHB2_RAT	Estradiol 17-beta-dehydrogenase 2	8612487	Cloning of rat 17 beta-hydroxysteroid dehydrogenase type 2 and characterization of tissue distribution and catalytic activity of rat type 1 and type 2 enzymes.

O74991	POF3_SCHPO	F-box/TPR repeat protein pof3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q80TN7	NAV3_MOUSE	Neuron navigator 3	12062803	Pore membrane and/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms.

P08678	CYAA_YEAST	Adenylate cyclase	2934138	DNA sequence and characterization of the S. cerevisiae gene encoding adenylate cyclase.

Q16557	PSG3_HUMAN	Pregnancy-specific beta-1-glycoprotein 3	3265688	Molecular cloning of a cDNA for human pregnancy-specific beta 1- glycoprotein: homology with human carcinoembryonic antigen and related proteins.

Q8BLA8	TRPA1_MOUSE	Transient receptor potential cation channel subfamily A member 1	15483558	TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells.

Q9GZZ6	ACH10_HUMAN	Neuronal acetylcholine receptor subunit alpha-10	11350119	Molecular cloning and mapping of the human nicotinic acetylcholine receptor alpha10 (CHRNA10).

P53925	YNL5_YEAST	Uncharacterized vacuolar membrane protein YNL115C	14562095	Global analysis of protein localization in budding yeast.

Q93ZN9	DAPAT_ARATH	LL-diaminopimelate aminotransferase, chloroplastic	16361515	An LL-diaminopimelate aminotransferase defines a novel variant of the lysine biosynthesis pathway in plants.

P32452	PHA2_YEAST	Putative prephenate dehydratase	14562095	Global analysis of protein localization in budding yeast.

Q9Y7K0	YGL3_SCHPO	UPF0659 protein C216.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q6I9Y2	THOC7_HUMAN	THO complex subunit 7 homolog	19059247	Nuclear localization of the pre-mRNA associating protein THOC7 depends upon its direct interaction with Fms tyrosine kinase interacting protein (FMIP).

Q86VS8	HOOK3_HUMAN	Protein Hook homolog 3	11238449	The Golgi-associated hook3 protein is a member of a novel family of microtubule-binding proteins.

P32644	ECM32_YEAST	Putative ATP-dependent RNA helicase ECM32	10836794	Mtt1 is a Upf1-like helicase that interacts with the translation termination factors and whose overexpression can modulate termination efficiency.

Q9UST7	SFC3_SCHPO	Transcription factor tau subunit sfc3	10906331	Isolation and cloning of four subunits of a fission yeast TFIIIC complex that includes an ortholog of the human regulatory protein TFIIICbeta.

P34697	SODC_CAEEL	Superoxide dismutase [Cu-Zn]	18073424	A measurable increase in oxidative damage due to reduction in superoxide detoxification fails to shorten the life span of long-lived mitochondrial mutants of Caenorhabditis elegans.

Q9P209	CEP72_HUMAN	Centrosomal protein of 72 kDa	19536135	Cep72 regulates the localization of key centrosomal proteins and proper bipolar spindle formation.

Q8K3I4	MYRIP_MOUSE	Rab effector MyRIP	12221080	Slac2-c (synaptotagmin-like protein homologue lacking C2 domains-c), a novel linker protein that interacts with Rab27, myosin Va/VIIa, and actin.

P41594	GRM5_HUMAN	Metabotropic glutamate receptor 5	7908515	Molecular cloning and the functional expression of two isoforms of human metabotropic glutamate receptor subtype 5.

Q9SB60	IPT4_ARATH	Adenylate isopentenyltransferase 4	15998742	Agrobacterium tumefaciens increases cytokinin production in plastids by modifying the biosynthetic pathway in the host plant.

P32597	STH1_YEAST	Nuclear protein STH1/NPS1	12072455	Yeast RSC function is required for organization of the cellular cytoskeleton via an alternative PKC1 pathway.

O60200	MDM35_YEAST	Mitochondrial distribution and morphology protein 35	11907266	Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae.

Q8NCE2	MTMRE_HUMAN	Myotubularin-related protein 14	17008356	A novel PtdIns3P and PtdIns(3,5)P2 phosphatase with an inactivating variant in centronuclear myopathy.

Q05196	PABP5_ARATH	Polyadenylate-binding protein 5	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

P31572	CAIB_ECOLI	Crotonobetainyl-CoA:carnitine CoA-transferase	7815937	Molecular characterization of the cai operon necessary for carnitine metabolism in Escherichia coli.

P18010	IPAA_SHIFL	Invasin ipaA	10545097	Binding of the Shigella protein IpaA to vinculin induces F-actin depolymerization.

P53692	SMC6_SCHPO	Structural maintenance of chromosomes protein 6	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P76010	YCGR_ECOLI	Flagellar brake protein YcgR	16920715	The PilZ domain is a receptor for the second messenger c-di-GMP: the PilZ domain protein YcgR controls motility in enterobacteria.

Q3KTM2	GDPD5_CHICK	Glycerophosphodiester phosphodiesterase domain-containing protein 5	19766572	The antioxidant enzyme Prdx1 controls neuronal differentiation by thiol-redox-dependent activation of GDE2.

P63244	GBLP_HUMAN	Guanine nucleotide-binding protein subunit beta-2-like 1	18954305	Structural basis and specificity of human otubain 1-mediated deubiquitination.

O59679	GEF3_SCHPO	Rho guanine nucleotide exchange factor gef3	14637153	Role of guanine nucleotide exchange factors for Rho family GTPases in the regulation of cell morphology and actin cytoskeleton in fission yeast.

Q8INZ1	GR36D_DROME	Putative chemosensory receptor 36d	14608037	Molecular evolution of the insect chemoreceptor gene superfamily in Drosophila melanogaster.

Q9UBT6	POLK_HUMAN	DNA polymerase kappa	10620008	Mutation enhancement by DINB1, a mammalian homologue of the Escherichia coli mutagenesis protein dinB.

P25146	INLA_LISMO	Internalin-A	12526809	Structure of internalin, a major invasion protein of Listeria monocytogenes, in complex with its human receptor E-cadherin.

Q5U9X3	GPC6A_DANRE	G-protein coupled receptor family C group 6 member A	15537883	Molecular determinants of ligand selectivity in a vertebrate odorant receptor.

Q9QWV4	MLF1_MOUSE	Myeloid leukemia factor 1	10523300	HLS7, a hemopoietic lineage switch gene homologous to the leukemia- inducing gene MLF1.

P81067	IRX3_MOUSE	Iroquois-class homeodomain protein IRX-3	17875669	The prepattern transcription factor Irx3 directs nephron segment identity.

P55281	CAD17_RAT	Cadherin-17	8207063	Liver-intestine cadherin: molecular cloning and characterization of a novel Ca(2+)-dependent cell adhesion molecule expressed in liver and intestine.

Q8NHE4	VA0E2_HUMAN	V-type proton ATPase subunit e 2	17350184	Molecular cloning and characterization of a novel form of the human vacuolar H+-ATPase e-subunit: an essential proton pump component.

P09951	SYN1_RAT	Synapsin-1	11867766	Neuronal nitric-oxide synthase localization mediated by a ternary complex with synapsin and CAPON.

Q09923	YAKC_SCHPO	Aldo-keto reductase yakc [NADP+]	12359080	Characterization of recombinant YakC of Schizosaccharomyces pombe showing YakC defines a new family of aldo-keto reductases.

O96017	CHK2_HUMAN	Serine/threonine-protein kinase Chk2	9889122	A human homologue of the checkpoint kinase Cds1 directly inhibits Cdc25 phosphatase.

Q17754	TIM9_CAEEL	Mitochondrial import inner membrane translocase subunit Tim9	15485840	Defective mitochondrial protein translocation precludes normal Caenorhabditis elegans development.

Q68G58	APEX2_MOUSE	DNA-(apurinic or apyrimidinic site) lyase 2	12573260	Characterization of the genomic structure and expression of the mouse Apex2 gene.

P56546	CTBP2_MOUSE	C-terminal-binding protein 2	16940172	Specific recognition of ZNF217 and other zinc finger proteins at a surface groove of C-terminal binding proteins.

P55824	FAF_DROME	Probable ubiquitin carboxyl-terminal hydrolase FAF	1295747	The fat facets gene is required for Drosophila eye and embryo development.

Q42569	C90A1_ARATH	Cytochrome P450 90A1	8612270	Brassinosteroids rescue the deficiency of CYP90, a cytochrome P450, controlling cell elongation and de-etiolation in Arabidopsis.

P09601	HMOX1_HUMAN	Heme oxygenase 1	3345742	Human heme oxygenase cDNA and induction of its mRNA by hemin.

Q9Y3D6	FIS1_HUMAN	Mitochondrial fission 1 protein	16118244	Regulation of mitochondrial fission and apoptosis by the mitochondrial outer membrane protein hFis1.

P52907	CAZA1_HUMAN	F-actin-capping protein subunit alpha-1	19922875	The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex.

P07666	SRYA_DROME	Serendipity locus protein alpha	2166703	The serendipity alpha gene encodes a membrane-associated protein required for the cellularization of the Drosophila embryo.

Q71U11	MATA2_CANAL	Mating-type-like protein A2	14622594	Evolution of a combinatorial transcriptional circuit: a case study in yeasts.

Q6E0V2	KTNA1_RAT	Katanin p60 ATPase-containing subunit A1	15215300	Axonal growth is sensitive to the levels of katanin, a protein that severs microtubules.

P00533	EGFR_HUMAN	Epidermal growth factor receptor	19172738	Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein.

P84736	PA2_TRIBL	Phospholipase A2 trimorphin	15225559	Biochemical characterization of phospholipase A2 (trimorphin) from the venom of the sonoran lyre snake Trimorphodon biscutatus lambda (family Colubridae).

Q8WXG1	RSAD2_HUMAN	Radical S-adenosyl methionine domain-containing protein 2	16108059	Analysis of ISG expression in chronic hepatitis C identifies viperin as a potential antiviral effector.

Q8VZ40	PUB14_ARATH	U-box domain-containing protein 14	19962994	PAH-domain-specific interactions of the Arabidopsis transcription coregulator SIN3-LIKE1 (SNL1) with telomere-binding protein 1 and ALWAYS EARLY2 Myb-DNA binding factors.

O97422	B3GI_DROME	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase I	12511570	Identification and characterization of three Drosophila melanogaster glucuronyltransferases responsible for the synthesis of the conserved glycosaminoglycan-protein linkage region of proteoglycans: two novel homologs exhibit broad specificity toward oligosaccharides from proteoglycans, glycoproteins, and glycosphingolipids.

P34982	OR1D2_HUMAN	Olfactory receptor 1D2	8097991	The OLFR1 gene encoding the HGMP07E putative olfactory receptor maps to the 17p13-->p12 region of the human genome and reveals an MspI restriction fragment length polymorphism.

Q05777	YL194_YEAST	Cell wall protein YLR194C	11016834	Up-regulation of genes encoding glycosylphosphatidylinositol (GPI)- attached proteins in response to cell wall damage caused by disruption of FKS1 in Saccharomyces cerevisiae.

Q8T4F7	ENA_DROME	Protein enabled	14762109	Cascade pathway of filopodia formation downstream of SCAR.

Q9WTY8	ZBT10_RAT	Zinc finger and BTB domain-containing protein 10	10075714	RIN ZF, a novel zinc finger gene, encodes proteins that bind to the CACC element of the gastrin promoter.

P28263	UBC8_YEAST	Ubiquitin-conjugating enzyme E2-24 kDa	1869573	Cloning and characterization of a Saccharomyces cerevisiae gene encoding a new member of the ubiquitin-conjugating protein family.

P35573	GDE_HUMAN	Glycogen debranching enzyme	17908927	A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease.

P22685	RLA0_DICDI	60S acidic ribosomal protein P0	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

O14508	SOCS2_HUMAN	Suppressor of cytokine signaling 2	9344848	Cloning and characterization of novel CIS family genes.

Q95T12	FLOWR_DROME	Calcium channel flower	19737521	A synaptic vesicle-associated Ca2+ channel promotes endocytosis and couples exocytosis to endocytosis.

Q13535	ATR_HUMAN	Serine/threonine-protein kinase ATR	9925639	A role for ATR in the DNA damage-induced phosphorylation of p53.

O81055	ASK16_ARATH	SKP1-like protein 16	12970487	Members of the Arabidopsis-SKP1-like gene family exhibit a variety of expression patterns and may play diverse roles in Arabidopsis.

O95150	TNF15_HUMAN	Tumor necrosis factor ligand superfamily member 15	11911831	TL1A is a TNF-like ligand for DR3 and TR6/DcR3 and functions as a T cell costimulator.

Q8L586	Y4958_ARATH	Uncharacterized membrane protein At4g09580	16618929	Mapping the Arabidopsis organelle proteome.

P27986	P85A_HUMAN	Phosphatidylinositol 3-kinase regulatory subunit alpha	7541045	Non-SH2 domains within insulin receptor substrate-1 and SHC mediate their phosphotyrosine-dependent interaction with the NPEY motif of the insulin-like growth factor I receptor.

O82339	CRF5_ARATH	Ethylene-responsive transcription factor CRF5	16832061	A subset of Arabidopsis AP2 transcription factors mediates cytokinin responses in concert with a two-component pathway.

Q24338	ESC_DROME	Polycomb protein esc	11124122	The Drosophila polycomb group proteins ESC and E(Z) are present in a complex containing the histone-binding protein p55 and the histone deacetylase RPD3.

P35270	SPRE_HUMAN	Sepiapterin reductase	9792819	Genomic organization and chromosomal localization of the human sepiapterin reductase gene.

Q9JI03	CO5A1_RAT	Collagen alpha-1(V) chain	10852920	Schwann cells synthesize type V collagen that contains a novel alpha 4 chain. Molecular cloning, biochemical characterization, and high affinity heparin binding of alpha 4(V) collagen.

Q9NPJ3	ACO13_HUMAN	Acyl-coenzyme A thioesterase 13	19170545	The mechanisms of human hotdog-fold thioesterase 2 (hTHEM2) substrate recognition and catalysis illuminated by a structure and function based analysis.

Q99705	MCHR1_HUMAN	Melanin-concentrating hormone receptor 1	10421367	Melanin-concentrating hormone is the cognate ligand for the orphan G- protein-coupled receptor SLC-1.

P54105	ICLN_HUMAN	Methylosome subunit pICln	9359436	Molecular cloning and expression of a chloride channel-associated protein pI(Cln) in human young red blood cells: association with actin.

P17256	KIME_RAT	Mevalonate kinase	2158094	Molecular cloning of mevalonate kinase and regulation of its mRNA levels in rat liver.

O75781	PALM_HUMAN	Paralemmin	9813098	Paralemmin, a prenyl-palmitoyl-anchored phosphoprotein abundant in neurons and implicated in plasma membrane dynamics and cell process formation.

P78545	ELF3_HUMAN	ETS-related transcription factor Elf-3	12624109	Distinct functional interactions of human Skn-1 isoforms with Ese-1 during keratinocyte terminal differentiation.

P97351	RS3A_MOUSE	40S ribosomal protein S3a	10713066	Novel interaction between the transcription factor CHOP (GADD153) and the ribosomal protein FTE/S3a modulates erythropoiesis.

Q24488	ROR1_DROME	Tyrosine-protein kinase transmembrane receptor Ror	8394009	Dror, a potential neurotrophic receptor gene, encodes a Drosophila homolog of the vertebrate Ror family of Trk-related receptor tyrosine kinases.

Q84RQ7	NIFU3_ARATH	NifU-like protein 3, chloroplastic	12553879	Iron-sulphur cluster assembly in plants: distinct NFU proteins in mitochondria and plastids from Arabidopsis thaliana.

P35218	CAH5A_HUMAN	Carbonic anhydrase 5A, mitochondrial	7490083	Genomic organization of the human gene (CA5) and pseudogene for mitochondrial carbonic anhydrase V and their localization to chromosomes 16q and 16p.

Q9TVM2	XPO1_DROME	Exportin-1	14638854	The Drosophila nucleoporin DNup88 localizes DNup214 and CRM1 on the nuclear envelope and attenuates NES-mediated nuclear export.

P16228	CATE_RAT	Cathepsin E	8491674	Cathepsin E in follicle associated epithelium of intestine and tonsils: localization to M cells and possible role in antigen processing.

Q99871	HAUS7_HUMAN	HAUS augmin-like complex subunit 7	11163772	Identification of two proteins, S14 and UIP1, that interact with UCH37.

Q8RWC9	CIPK1_ARATH	CBL-interacting serine/threonine-protein kinase 1	11230129	The NAF domain defines a novel protein-protein interaction module conserved in Ca(2+)-regulated kinases.

Q16222	UAP1_HUMAN	UDP-N-acetylhexosamine pyrophosphorylase	9603950	The eukaryotic UDP-N-acetylglucosamine pyrophosphorylases: gene cloning, protein expression, and catalytic mechanism.

P40900	ISP4_SCHPO	Sexual differentiation process protein isp4	7954893	Identification and characterization of genes induced during sexual differentiation in Schizosaccharomyces pombe.

Q6DBY2	NAA50_DANRE	N-alpha-acetyltransferase 50, NatE catalytic subunit	16484612	Embryonic growth-associated protein is one subunit of a novel N- terminal acetyltransferase complex essential for embryonic vascular development.

Q9HBE4	IL21_HUMAN	Interleukin-21	11081504	Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function.

P25626	IMG1_YEAST	54S ribosomal protein IMG1, mitochondrial	12392552	Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components.

Q09927	PPR1_SCHPO	L-azetidine-2-carboxylic acid acetyltransferase	12761200	Characterization of novel acetyltransferases found in budding and fission yeasts that detoxify a proline analogue, azetidine-2- carboxylic acid.

Q64151	SEM4C_MOUSE	Semaphorin-4C	10318831	A PDZ protein regulates the distribution of the transmembrane semaphorin, M-SemF.

Q80TZ9	RERE_MOUSE	Arginine-glutamic acid dipeptide repeats protein	14645126	Atrophin 2 recruits histone deacetylase and is required for the function of multiple signaling centers during mouse embryogenesis.

P48612	PELO_DROME	Protein pelota	7588080	The pelota locus encodes a protein required for meiotic cell division: an analysis of G2/M arrest in Drosophila spermatogenesis.

P87133	MU143_SCHPO	Meiotically up-regulated gene 143 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P43355	MAGA1_HUMAN	Melanoma-associated antigen 1	1840703	A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma.

Q9JK71	MAGI3_RAT	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3	16316992	Proteomic analysis of beta1-adrenergic receptor interactions with PDZ scaffold proteins.

Q6DCQ1	IRX2_XENLA	Iroquois-class homeodomain protein irx-2	19268445	The Xenopus Irx genes are essential for neural patterning and define the border between prethalamus and thalamus through mutual antagonism with the anterior repressors Fezf and Arx.

O60244	MED14_HUMAN	Mediator of RNA polymerase II transcription subunit 14	10235267	Composite co-activator ARC mediates chromatin-directed transcriptional activation.

Q24145	SHARK_DROME	Tyrosine-protein kinase shark	7892198	Shark, a Src homology 2, ankyrin repeat, tyrosine kinase, is expressed on the apical surfaces of ectodermal epithelia.

O43929	ORC4_HUMAN	Origin recognition complex subunit 4	9353276	Identification of HsORC4, a member of the human origin of replication recognition complex.

Q12489	YD012_YEAST	Uncharacterized protein YDL012C	12514182	Bipartite signals mediate subcellular targeting of tail-anchored membrane proteins in Saccharomyces cerevisiae.

Q01113	IL9R_HUMAN	Interleukin-9 receptor	1376929	Expression cloning of the murine and human interleukin 9 receptor cDNAs.

Q9SM64	SODM_PRUPE	Superoxide dismutase [Mn], mitochondrial	12073034	Molecular cloning, characterisation and expression of a manganese superoxide dismutase gene from peach (Prunus persica L. Batsch).

P08572	CO4A2_HUMAN	Collagen alpha-2(IV) chain	10625665	Canstatin, a novel matrix-derived inhibitor of angiogenesis and tumor growth.

P37679	SGBU_ECOLI	Putative L-ribulose-5-phosphate 3-epimerase sgbU	10913097	Role of the yiaR and yiaS genes of Escherichia coli in metabolism of endogenously formed L-xylulose.

P84280	PA2C_RANPA	Palustrin-2c	11087945	Multiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris.

Q9P0U1	TOM7_HUMAN	Mitochondrial import receptor subunit TOM7 homolog	12198123	Insertion and assembly of human tom7 into the preprotein translocase complex of the outer mitochondrial membrane.

P38337	SHG1_YEAST	COMPASS component SHG1	11805083	COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression.

P24311	COX7B_HUMAN	Cytochrome c oxidase subunit 7B, mitochondrial	8382530	Isolation of a cDNA specifying subunit VIIb of human cytochrome c oxidase.

Q9D1C2	CBY1_MOUSE	Protein chibby homolog 1	17261658	Chibby, an antagonist of the Wnt/beta-catenin pathway, facilitates cardiomyocyte differentiation of murine embryonic stem cells.

Q02887	ATG21_YEAST	Autophagy-related protein 21	15155809	Atg21 is a phosphoinositide binding protein required for efficient lipidation and localization of Atg8 during uptake of aminopeptidase I by selective autophagy.

O73691	EGR1_CHICK	Early growth response protein 1	9501495	Evolutionary conservation of the immediate-early gene ZENK.

P35712	SOX6_HUMAN	Transcription factor SOX-6	1614875	A conserved family of genes related to the testis determining gene, SRY.

Q08673	SRL1_YEAST	Cell wall protein SRL1	13679573	Widespread cytoplasmic mRNA transport in yeast: identification of 22 bud-localized transcripts using DNA microarray analysis.

Q09826	SDS23_SCHPO	Protein sds23/moc1	8978689	Requirement for PP1 phosphatase and 20S cyclosome/APC for the onset of anaphase is lessened by the dosage increase of a novel gene sds23+.

P63247	GBLP_CHICK	Guanine nucleotide-binding protein subunit beta-2-like 1	2499885	Physical linkage of a guanine nucleotide-binding protein-related gene to the chicken major histocompatibility complex.

O60512	B4GT3_HUMAN	Beta-1,4-galactosyltransferase 3	9405390	A family of human beta4-galactosyltransferases. Cloning and expression of two novel UDP-galactose:beta-n-acetylglucosamine beta1, 4-galactosyltransferases, beta4Gal-T2 and beta4Gal-T3.

Q99811	PRRX2_HUMAN	Paired mesoderm homeobox protein 2	9665387	Modulation of the human homeobox genes PRX-2 and HOXB13 in scarless fetal wounds.

P16152	CBR1_HUMAN	Carbonyl reductase [NADPH] 1	18449627	Inhibition of polymorphic human carbonyl reductase 1 (CBR1) by the cardioprotectant flavonoid 7-monohydroxyethyl rutoside (monoHER).

Q96Q15	SMG1_HUMAN	Serine/threonine-protein kinase SMG1	11544179	Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay.

P40995	SCD1_SCHPO	Rho guanine nucleotide exchange factor scd1	7923372	Cooperative interaction of S. pombe proteins required for mating and morphogenesis.

Q9USR0	YN19_SCHPO	Uncharacterized WD repeat-containing protein C577.09	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

A6JUQ6	CLVS2_RAT	Clavesin-2	19651769	The clavesin family: neuron-specific lipid- and clathrin-binding Sec14 proteins regulating lysosomal morphology.

P50582	HSK1_SCHPO	Cell cycle serine/threonine-protein kinase hsk1	10411894	Cell cycle regulation of Dfp1, an activator of the Hsk1 protein kinase.

O14195	YF07_SCHPO	Uncharacterized N-acetyltransferase C56E4.07	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12199	TIP41_YEAST	Type 2A phosphatase activator TIP41	11741537	TIP41 interacts with TAP42 and negatively regulates the TOR signaling pathway.

Q9D687	S6A19_MOUSE	Sodium-dependent neutral amino acid transporter B(0)AT1	15044460	Molecular cloning of mouse amino acid transport system B(0), a neutral amino acid transporter related to Hartnup disorder.

Q9VMD6	RETM_DROME	Protein real-time	15700158	A novel family of mitochondrial proteins is represented by the Drosophila genes slmo, preli-like and real-time.

P12688	YPK1_YEAST	Serine/threonine-protein kinase YPK1	10825204	Sli2 (Ypk1), a homologue of mammalian protein kinase SGK, is a downstream kinase in the sphingolipid-mediated signaling pathway of yeast.

Q91XN4	BAMBI_RAT	BMP and activin membrane-bound inhibitor homolog	12933693	Expression of Bambi is widespread in juvenile and adult rat tissues and is regulated in male germ cells.

P27882	ERV1_YEAST	Mitochondrial FAD-linked sulfhydryl oxidase ERV1	11493598	An essential function of the mitochondrial sulfhydryl oxidase Erv1p/ALR in the maturation of cytosolic Fe/S proteins.

Q54RB7	SHKA_DICDI	Dual specificity protein kinase shkA	11274054	An SH2-domain containing kinase is a negative regulator of the phosphatidylinositol-3 kinase pathway.

Q9NJP9	GLPK_TRYBB	Glycerol kinase, glycosomal	10759857	Glycerol kinase of Trypanosoma brucei. Cloning, molecular characterization and mutagenesis.

P48164	RS7B_YEAST	40S ribosomal protein S7-B	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q24212	STNB_DROME	Protein stoned-B	11069931	The products of the Drosophila stoned locus interact with synaptic vesicles via synaptotagmin.

Q69ZS6	SV2C_MOUSE	Synaptic vesicle glycoprotein 2C	12687700	Differential distribution and developmental expression of synaptic vesicle protein 2 isoforms in the mouse retina.

Q9USR9	CENPC_SCHPO	Centromere protein 3	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q5EGZ1	ACE2_RAT	Angiotensin-converting enzyme 2	15231706	The novel angiotensin-converting enzyme (ACE) homolog, ACE2, is selectively expressed by adult Leydig cells of the testis.

Q9Y570	PPME1_HUMAN	Protein phosphatase methylesterase 1	10318862	A protein phosphatase methylesterase (PME-1) is one of several novel proteins stably associating with two inactive mutants of protein phosphatase 2A.

P69851	DAD4_YEAST	DASH complex subunit DAD4	15640796	The yeast DASH complex forms closed rings on microtubules.

P40339	RFC4_YEAST	Replication factor C subunit 4	8063832	Cloning and characterization of the essential Saccharomyces cerevisiae RFC4 gene encoding the 37-kDa subunit of replication factor C.

P62306	RUXF_HUMAN	Small nuclear ribonucleoprotein F	11991638	Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.

P32791	FRE1_YEAST	Ferric/cupric reductase transmembrane component 1	17507646	Probing the membrane environment of the TOR kinases reveals functional interactions between TORC1, actin, and membrane trafficking in Saccharomyces cerevisiae.

P52735	VAV2_HUMAN	Guanine nucleotide exchange factor VAV2	7762982	Identification of VAV2 on 9q34 and its exclusion as the tuberous sclerosis gene TSC1.

O60566	BUB1B_HUMAN	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta	12925705	Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss.

O00305	CACB4_HUMAN	Voltage-dependent L-type calcium channel subunit beta-4	11880487	Alternative splicing of the beta 4 subunit has alpha 1 subunit subtype-specific effects on Ca2+ channel gating.

O13166	TLE2_DANRE	Protein groucho-2	16326386	Groucho-associated transcriptional repressor ripply1 is required for proper transition from the presomitic mesoderm to somites.

P24867	PCL1_YEAST	PHO85 cyclin-1	7973730	Cell cycle control by a complex of the cyclin HCS26 (PCL1) and the kinase PHO85.

Q02864	YP071_YEAST	Uncharacterized protein YPL071C	14562095	Global analysis of protein localization in budding yeast.

Q9GZR7	DDX24_HUMAN	ATP-dependent RNA helicase DDX24	10936056	Cloning and characterization of human DDX24 and mouse Ddx24, two novel putative DEAD-box proteins, and mapping DDX24 to human chromosome 14q32.

Q54I18	SMEK_DICDI	Suppressor of Mek1	16107728	Loss of SMEK, a novel, conserved protein, suppresses MEK1 null cell polarity, chemotaxis, and gene expression defects.

Q08GK9	HSPL_MULSU	Protamine-like protein	16965539	A unique vertebrate histone H1-related protamine-like protein results in an unusual sperm chromatin organization.

Q9TW45	PAR1_CAEEL	Serine/threonine-protein kinase par-1	12490197	PAR-1 is required for morphogenesis of the Caenorhabditis elegans vulva.

Q9C0X3	YBBF_SCHPO	Putative uncharacterized protein C13G1.15c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O95399	UTS2_HUMAN	Urotensin-2	10499587	Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14.

Q14714	SSPN_HUMAN	Sarcospan	9395445	Sarcospan, the 25-kDa transmembrane component of the dystrophin- glycoprotein complex.

P39979	HPA3_YEAST	N-acetyltransferase HPA3	14562095	Global analysis of protein localization in budding yeast.

P42530	DIS2_DICDI	Discoidin-2	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q9URV3	MUG2_SCHPO	Meiotically up-regulated gene 2 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Y738	MIS12_SCHPO	Centromere protein mis12	17035632	Reconstruction of the kinetochore during meiosis in fission yeast Schizosaccharomyces pombe.

Q9NP99	TREM1_HUMAN	Triggering receptor expressed on myeloid cells 1	10799849	Inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes.

Q6IN36	WIPF1_RAT	WAS/WASL-interacting protein family member 1	11687573	The rat homologue of Wiskott-Aldrich syndrome protein (WASP)- interacting protein (WIP) associates with actin filaments, recruits N- WASP from the nucleus, and mediates mobilization of actin from stress fibers in favor of filopodia formation.

B7ZRU9	EVI1A_XENLA	MDS1 and EVI1 complex locus protein EVI1-A	16574097	Evi1 is specifically expressed in the distal tubule and duct of the Xenopus pronephros and plays a role in its formation.

P0C2B6	RM51_BOVIN	39S ribosomal protein L51, mitochondrial	11551941	The large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present.

Q38857	XTH22_ARATH	Xyloglucan endotransglucosylase/hydrolase protein 22	7580251	Arabidopsis TCH4, regulated by hormones and the environment, encodes a xyloglucan endotransglycosylase.

P39964	CEF1_SCHPO	Pre-mRNA-splicing factor cef1	11884590	Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

O95983	MBD3_HUMAN	Methyl-CpG-binding domain protein 3	9774669	Identification and characterization of a family of mammalian methyl- CpG binding proteins.

O82302	P2C29_ARATH	Protein phosphatase 2C 29	16112663	POL and related phosphatases are dosage-sensitive regulators of meristem and organ development in Arabidopsis.

Q13131	AAPK1_HUMAN	5'-AMP-activated protein kinase catalytic subunit alpha-1	8557660	Mammalian AMP-activated protein kinase subfamily.

P62196	PRS8_MOUSE	26S protease regulatory subunit 8	8598193	Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1.

P84784	RNHI1_THEGA	Ribonuclease	15474506	Purification of a novel ribonuclease from dried fruiting bodies of the edible wild mushroom Thelephora ganbajun.

P22214	SEC22_YEAST	Protein transport protein SEC22	11001058	Topological restriction of SNARE-dependent membrane fusion.

P32864	RAEP_YEAST	Rab proteins geranylgeranyltransferase component A	8132658	The Saccharomyces cerevisiae MSI4 gene encodes the yeast counterpart of component A of Rab geranylgeranyltransferase.

O14063	IMA1_SCHPO	Importin subunit alpha-1	15937127	The fission yeast Schizosaccharomyces pombe has two importin-alpha proteins, Imp1p and Cut15p, which have common and unique functions in nucleocytoplasmic transport and cell cycle progression.

O13828	DCP2_SCHPO	mRNA decapping complex subunit 2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P62891	RL39_HUMAN	60S ribosomal protein L39	8764829	Molecular cloning of a cDNA encoding human ribosomal protein L39.

Q05652	KPEL_DROME	Serine/threonine-protein kinase pelle	7635064	Interaction of the pelle kinase with the membrane-associated protein tube is required for transduction of the dorsoventral signal in Drosophila embryos.

P15311	EZRI_HUMAN	Ezrin	19555689	MCC, a new interacting protein for Scrib, is required for cell migration in epithelial cells.

P48637	GSHB_HUMAN	Glutathione synthetase	7646467	Sequencing and expression of a cDNA for human glutathione synthetase.

Q9SJ81	FLA7_ARATH	Fasciclin-like arabinogalactan protein 7	12805588	Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis.

Q91YW3	DNJC3_MOUSE	DnaJ homolog subfamily C member 3	8666242	Cloning, expression, and cellular localization of the oncogenic 58- kDa inhibitor of the RNA-activated human and mouse protein kinase.

Q60929	MEF2A_MOUSE	Myocyte-specific enhancer factor 2A	17785444	Nemo-like kinase-myocyte enhancer factor 2A signaling regulates anterior formation in Xenopus development.

P78352	DLG4_HUMAN	Disks large homolog 4	12151521	Postsynaptic targeting of alternative postsynaptic density-95 isoforms by distinct mechanisms.

A3FIN4	AT8B5_MOUSE	Probable phospholipid-transporting ATPase FetA	19657017	Identification of a novel mouse P4-ATPase family member highly expressed during spermatogenesis.

Q99MR1	PERQ1_MOUSE	PERQ amino acid-rich with GYF domain-containing protein 1	12771153	Two novel proteins that are linked to insulin-like growth factor (IGF-I) receptors by the Grb10 adapter and modulate IGF-I signaling.

Q10E50	PLA23_ORYSJ	Phospholipase A2 homolog 3	10608658	Plant low-molecular-weight phospholipase A2S (PLA2s) are structurally related to the animal secretory PLA2s and are present as a family of isoforms in rice (Oryza sativa).

Q86S05	LIG_DROME	Protein lingerer	12524348	Lingerer, a Drosophila gene involved in initiation and termination of copulation, encodes a set of novel cytoplasmic proteins.

P08514	ITA2B_HUMAN	Integrin alpha-IIb	2439501	Structure of the platelet membrane glycoprotein IIb. Homology to the alpha subunits of the vitronectin and fibronectin membrane receptors.

Q8CFA1	IRAK2_MOUSE	Interleukin-1 receptor-associated kinase-like 2	12220507	Identification and characterization of murine IRAK-2.

P15228	AEP1_MESMA	Toxin BmKAEP	11298767	Molecular characterization of an anti-epilepsy peptide from the scorpion Buthus martensi Karsch.

Q9QX74	SHAN2_RAT	SH3 and multiple ankyrin repeat domains protein 2	16293618	Shank2 associates with and regulates Na+/H+ exchanger 3.

Q9UKT4	FBX5_HUMAN	F-box only protein 5	11988738	E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1).

O13926	YF66_SCHPO	UPF0665 family protein C23C4.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P15509	CSF2R_HUMAN	Granulocyte-macrophage colony-stimulating factor receptor subunit alpha	1358805	Arrangement and localization of the human GM-CSF receptor alpha chain gene CSF2RA within the X-Y pseudoautosomal region.

P08069	IGF1R_HUMAN	Insulin-like growth factor 1 receptor	11162456	Autophosphorylation of the insulin-like growth factor I receptor cytoplasmic domain.

Q15569	TESK1_HUMAN	Dual specificity testis-specific protein kinase 1	8537404	Identification and characterization of a novel protein kinase, TESK1, specifically expressed in testicular germ cells.

P45884	ATTA_DROME	Attacin-A	10767526	Two attacin antibacterial genes of Drosophila melanogaster.

O95229	ZWINT_HUMAN	ZW10 interactor	15502821	A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1.

Q80U63	MFN2_MOUSE	Mitofusin-2	12527753	Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development.

Q9Y333	LSM2_HUMAN	U6 snRNA-associated Sm-like protein LSm2	10523320	A doughnut-shaped heteromer of human Sm-like proteins binds to the 3'-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro.

P53379	MKC7_YEAST	Aspartic proteinase MKC7	16087741	Yapsins are a family of aspartyl proteases required for cell wall integrity in Saccharomyces cerevisiae.

Q00417	TCF7_MOUSE	Transcription factor 7	1827138	Cloning of murine TCF-1, a T cell-specific transcription factor interacting with functional motifs in the CD3-epsilon and T cell receptor alpha enhancers.

Q9SWW6	CESA7_ARATH	Cellulose synthase A catalytic subunit 7 [UDP-forming]	10330464	The irregular xylem3 locus of Arabidopsis encodes a cellulose synthase required for secondary cell wall synthesis.

Q15054	DPOD3_HUMAN	DNA polymerase delta subunit 3	16510448	Functional roles of p12, the fourth subunit of human DNA polymerase delta.

P19734	DMPP_PSEUF	Phenol hydroxylase P5 protein	2254259	In vitro analysis of polypeptide requirements of multicomponent phenol hydroxylase from Pseudomonas sp. strain CF600.

O94455	YFFE_SCHPO	Uncharacterized calcium-binding protein C1687.14c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q09161	NCBP1_HUMAN	Nuclear cap-binding protein subunit 1	17190602	Human mRNA export machinery recruited to the 5' end of mRNA.

P48059	LIMS1_HUMAN	LIM and senescent cell antigen-like-containing domain protein 1	19074270	The structural basis of integrin-linked kinase-PINCH interactions.

P58340	MLF1_HUMAN	Myeloid leukemia factor 1	15861129	Myeloid leukemia factor 1 regulates p53 by suppressing COP1 via COP9 signalosome subunit 3.

Q9EQ47	V1R44_MOUSE	Vomeronasal type-1 receptor 44	11116090	Sequence diversity and genomic organization of vomeronasal receptor genes in the mouse.

Q15018	F175B_HUMAN	BRISC complex subunit Abro1	19214193	K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC- associated Brcc36 and proteasomal Poh1.

P33330	SERC_YEAST	Phosphoserine aminotransferase	8017107	A gene from Saccharomyces cerevisiae which codes for a protein with significant homology to the bacterial 3-phosphoserine aminotransferase.

P40371	PP2C1_SCHPO	Protein phosphatase 2C homolog 1	8196617	Protein phosphatase 2C, encoded by ptc1+, is important in the heat shock response of Schizosaccharomyces pombe.

P84508	TX2_CERMR	Beta-theraphotoxin-Cm1b	16267209	Four novel tarantula toxins as selective modulators of voltage-gated sodium channel subtypes.

Q9T0J9	GBIS1_ARATH	(Z)-gamma-bisabolene synthase 1	16297850	Microarray expression profiling and functional characterization of AtTPS genes: duplicated Arabidopsis thaliana sesquiterpene synthase genes At4g13280 and At4g13300 encode root-specific and wound-inducible (Z)-gamma-bisabolene synthases.

Q8TDE3	RNAS8_HUMAN	Ribonuclease 8	11861908	RNase 8, a novel RNase A superfamily ribonuclease expressed uniquely in placenta.

P17661	DESM_HUMAN	Desmin	9697706	Missense mutations in desmin associated with familial cardiac and skeletal myopathy.

Q9FUT3	AB23B_ARATH	ABC transporter B family member 23, mitochondrial	17517886	Functional characterization of AtATM1, AtATM2, and AtATM3, a subfamily of Arabidopsis half-molecule ATP-binding cassette transporters implicated in iron homeostasis.

Q9XHE6	C71DF_MENPI	Cytochrome P450 71D15	10415126	Regiospecific cytochrome P450 limonene hydroxylases from mint (Mentha) species: cDNA isolation, characterization, and functional expression of (-)-4S-limonene-3-hydroxylase and (-)-4S-limonene-6- hydroxylase.

Q63089	S22A1_RAT	Solute carrier family 22 member 1	9808712	Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs.

P24468	COT2_HUMAN	COUP transcription factor 2	18798693	Identification of COUP-TFII orphan nuclear receptor as a retinoic acid-activated receptor.

Q924S7	SPRE2_MOUSE	Sprouty-related, EVH1 domain-containing protein 2	15580519	Expression and subcellular localization of Spred proteins in mouse and human tissues.

Q04779	RCO1_YEAST	Transcriptional regulatory protein RCO1	16286008	Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex.

Q39231	SUC2_ARATH	Sucrose transport protein SUC2	12954621	Substrate specificity of the Arabidopsis thaliana sucrose transporter AtSUC2.

P11362	FGFR1_HUMAN	Basic fibroblast growth factor receptor 1	1846977	Fibroblast growth factor receptors from liver vary in three structural domains.

P40616	ARL1_HUMAN	ADP-ribosylation factor-like protein 1	9624189	Phospholipid- and GTP-dependent activation of cholera toxin and phospholipase D by human ADP-ribosylation factor-like protein 1 (HARL1).

P25349	YCP4_YEAST	Flavoprotein-like protein YCP4	14562095	Global analysis of protein localization in budding yeast.

P40201	CHD1_MOUSE	Chromodomain-helicase-DNA-binding protein 1	8460153	A mammalian DNA-binding protein that contains a chromodomain and an SNF2/SWI2-like helicase domain.

O88398	AVIL_MOUSE	Advillin	9649432	Identification of novel stress-induced genes downstream of chop.

P97401	SFRP3_MOUSE	Secreted frizzled-related protein 3	9096311	A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors.

Q5XUX0	FBX31_HUMAN	F-box only protein 31	19412162	F-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damage.

P61088	UBE2N_HUMAN	Ubiquitin-conjugating enzyme E2 N	17135271	Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation.

O13936	SPT5_SCHPO	Transcription elongation factor spt5	11893740	Interactions between fission yeast mRNA capping enzymes and elongation factor Spt5.

P53273	YG35_YEAST	Uncharacterized vacuolar membrane protein YGR125W	14562095	Global analysis of protein localization in budding yeast.

Q16512	PKN1_HUMAN	Serine/threonine-protein kinase N1	18006505	The Rac1 polybasic region is required for interaction with its effector PRK1.

Q9GNQ1	LPS18_LIMMA	18 kDa learning-associated protein of slug	11168596	Identification and expression of a novel gene in odour-taste associative learning in the terrestrial slug.

Q39163	TGA5_ARATH	Transcription factor TGA5	8718629	Interactions between distinct types of DNA binding proteins enhance binding to ocs element promoter sequences.

P06700	SIR2_YEAST	NAD-dependent histone deacetylase SIR2	9214640	Localization of Sir2p: the nucleolus as a compartment for silent information regulators.

P05107	ITB2_HUMAN	Integrin beta-2	1694220	Distinct mutations in two patients with leukocyte adhesion deficiency and their functional correlates.

Q6UWZ7	F175A_HUMAN	BRCA1-A complex subunit Abraxas	17525340	Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response.

Q09763	GEF1_SCHPO	Rho guanine nucleotide exchange factor gef1	12972551	Gef1p and Scd1p, the Two GDP-GTP exchange factors for Cdc42p, form a ring structure that shrinks during cytokinesis in Schizosaccharomyces pombe.

Q18273	HM43_CAEEL	Homeobox protein ceh-43	11747075	The Caenorhabditis elegans distal-less ortholog ceh-43 is required for development of the anterior hypodermis.

Q07824	TPO1_YEAST	Polyamine transporter 1	13679573	Widespread cytoplasmic mRNA transport in yeast: identification of 22 bud-localized transcripts using DNA microarray analysis.

P20434	RPAB1_YEAST	DNA-directed RNA polymerases I, II, and III subunit RPABC1	2186966	Subunits shared by eukaryotic nuclear RNA polymerases.

Q9VHV5	ARL8_DROME	ADP-ribosylation factor-like protein 8	15331635	Novel small GTPase subfamily capable of associating with tubulin is required for chromosome segregation.

Q9DAU1	CNPY3_MOUSE	Protein canopy homolog 3	16338228	A molecule that is associated with Toll-like receptor 4 and regulates its cell surface expression.

P30664	MCM4B_XENLA	DNA replication licensing factor mcm4-B	8901561	Phosphorylation of MCM4 by cdc2 protein kinase inhibits the activity of the minichromosome maintenance complex.

P25454	RAD51_YEAST	DNA repair protein RAD51	1581961	Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein.

Q23917	PDE2_DICDI	3',5'-cyclic-nucleotide phosphodiesterase regA	17659086	High-throughput analysis of spatio-temporal dynamics in Dictyostelium.

Q96A70	ADC_HUMAN	Arginine decarboxylase	14738999	Expression of human arginine decarboxylase, the biosynthetic enzyme for agmatine.

Q9U1H9	NXF1_DROME	Nuclear RNA export factor 1	11780633	NXF1/p15 heterodimers are essential for mRNA nuclear export in Drosophila.

Q02936	HH_DROME	Protein hedgehog	1394430	Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog.

P41004	SMC4_SCHPO	Structural maintenance of chromosomes protein 4	15148393	Cti1/C1D interacts with condensin SMC hinge and supports the DNA repair function of condensin.

Q99PF4	CAD23_MOUSE	Cadherin-23	11386759	Mutations in Cdh23 cause nonsyndromic hearing loss in waltzer mice.

Q13586	STIM1_HUMAN	Stromal interaction molecule 1	17905723	STIM2 protein mediates distinct store-dependent and store-independent modes of CRAC channel activation.

Q9LHS9	RBE_ARATH	Probable transcriptional regulator RABBIT EARS	14681191	RABBIT EARS, encoding a SUPERMAN-like zinc finger protein, regulates petal development in Arabidopsis thaliana.

Q8TCW9	PKR1_HUMAN	Prokineticin receptor 1	12427552	Molecular cloning and characterization of prokineticin receptors.

O74362	ESF2_SCHPO	Pre-rRNA-processing protein esf2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q92729	PTPRU_HUMAN	Receptor-type tyrosine-protein phosphatase U	17622474	Involvement of beta3A subunit of adaptor protein-3 in intracellular trafficking of receptor-like protein tyrosine phosphatase PCP-2.

Q3TFD2	PCAT1_MOUSE	Lysophosphatidylcholine acyltransferase 1	16704971	Cloning and characterization of mouse lung-type acyl- CoA:lysophosphatidylcholine acyltransferase 1 (LPCAT1): expression in alveolar type II cells and possible involvement in surfactant production.

O74991	POF3_SCHPO	F-box/TPR repeat protein pof3	16997270	Fission yeast Mcl1 interacts with SCF(Pof3) and is required for centromere formation.

Q63624	SFR19_RAT	Splicing factor, arginine/serine-rich 19	8692929	The C-terminal domain of the largest subunit of RNA polymerase II interacts with a novel set of serine/arginine-rich proteins.

Q9UM73	ALK_HUMAN	ALK tyrosine kinase receptor	9174053	ALK, the chromosome 2 gene locus altered by the t(2;5) in non- Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK).

Q9Z1T5	DEAF1_MOUSE	Deformed epidermal autoregulatory factor 1 homolog	18826651	Deaf-1 regulates epithelial cell proliferation and side-branching in the mammary gland.

Q02505	MUC3A_HUMAN	Mucin-3A	9334251	MUC3 human intestinal mucin. Analysis of gene structure, the carboxyl terminus, and a novel upstream repetitive region.

P47002	SSY5_YEAST	SPS-sensor serine protease component SSY5	11154269	Genetic and biochemical analysis of the yeast plasma membrane Ssy1p- Ptr3p-Ssy5p sensor of extracellular amino acids.

Q9DDE3	ACES_DANRE	Acetylcholinesterase	11016933	Zebrafish acetylcholinesterase is encoded by a single gene localized on linkage group 7. gene structure and polymorphism; molecular forms and expression pattern during development.

O14044	PNO1_SCHPO	Pre-rRNA-processing protein pno1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O13916	HCN1_SCHPO	Anaphase-promoting complex subunit hcn1	9264466	Distinct subunit functions and cell cycle regulated phosphorylation of 20S APC/cyclosome required for anaphase in fission yeast.

P18509	PACA_HUMAN	Pituitary adenylate cyclase-activating polypeptide	1730060	Structure of the human pituitary adenylate cyclase activating polypeptide (PACAP) gene.

Q80UF7	TCAM1_MOUSE	TIR domain-containing adapter molecule 1	12855817	Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway.

P16467	PDC5_YEAST	Pyruvate decarboxylase isozyme 2	14562095	Global analysis of protein localization in budding yeast.

O94583	YQ7B_SCHPO	Uncharacterized protein C1442.11c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NZV8	KCND2_HUMAN	Potassium voltage-gated channel subfamily D member 2	11102480	Localization and enhanced current density of the Kv4.2 potassium channel by interaction with the actin-binding protein filamin.

Q12033	PALA_YEAST	pH-response regulator protein palA/RIM20	11698381	Yeast PalA/AIP1/Alix homolog Rim20p associates with a PEST-like region and is required for its proteolytic cleavage.

P56817	BACE1_HUMAN	Beta-secretase 1	10531052	Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE.

P0AB71	ALF_ECOLI	Fructose-bisphosphate aldolase class 2	8436219	Identification of zinc-binding ligands in the class II fructose-1,6- bisphosphate aldolase of Escherichia coli.

Q64701	RBL1_MOUSE	Retinoblastoma-like protein 1	11571651	Association of UNP, a ubiquitin-specific protease, with the pocket proteins pRb, p107 and p130.

P13051	UNG_HUMAN	Uracil-DNA glycosylase	7671300	Crystal structure of human uracil-DNA glycosylase in complex with a protein inhibitor: protein mimicry of DNA.

Q9Y6Q6	TNR11_HUMAN	Tumor necrosis factor receptor superfamily member 11A	15750601	The molecular scaffold Gab2 is a crucial component of RANK signaling and osteoclastogenesis.

P38631	FKS1_YEAST	1,3-beta-glucan synthase component FKS1	7649185	Characterization and gene cloning of 1,3-beta-D-glucan synthase from Saccharomyces cerevisiae.

Q9H9S5	FKRP_HUMAN	Fukutin-related protein	15213246	Subcellular localization of fukutin and fukutin-related protein in muscle cells.

Q9HDV1	MU180_SCHPO	Meiotically up-regulated gene 180 protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P62993	GRB2_HUMAN	Growth factor receptor-bound protein 2	10980613	Generation of novel cytoplasmic forms of protein tyrosine phosphatase epsilon by proteolytic processing and translational control.

P10716	CLC4F_RAT	C-type lectin domain family 4 member F	2836387	Molecular cloning and sequencing of a cDNA for a carbohydrate binding receptor unique to rat Kupffer cells.

Q9NS71	GKN1_HUMAN	Gastrokine-1	10835488	Isolation of two novel genes, down-regulated in gastric cancer.

P38063	KPR4_YEAST	Ribose-phosphate pyrophosphokinase 4	14562095	Global analysis of protein localization in budding yeast.

O43184	ADA12_HUMAN	Disintegrin and metalloproteinase domain-containing protein 12	9417060	A novel, secreted form of human ADAM 12 (meltrin alpha) provokes myogenesis in vivo.

P48058	GRIA4_HUMAN	Glutamate receptor 4	8589990	Cloning, expression and pharmacological characterization of a human glutamate receptor: hGluR4.

Q9FMW9	ICMTA_ARATH	Protein-S-isoprenylcysteine O-methyltransferase A	18641086	Functional analysis of Arabidopsis postprenylation CaaX processing enzymes and their function in subcellular protein targeting.

Q8CJG0	AGO2_MOUSE	Protein argonaute-2	12526743	Short-interfering-RNA-mediated gene silencing in mammalian cells requires Dicer and eIF2C translation initiation factors.

P17505	MDHM_YEAST	Malate dehydrogenase, mitochondrial	11502169	Yeast mitochondrial dehydrogenases are associated in a supramolecular complex.

Q06510	TAZ1_YEAST	Lysophosphatidylcholine acyltransferase	15588229	Ypr140wp, 'the yeast tafazzin', displays a mitochondrial lysophosphatidylcholine (lyso-PC) acyltransferase activity related to triacylglycerol and mitochondrial lipid synthesis.

P62142	PP1B_RAT	Serine/threonine-protein phosphatase PP1-beta catalytic subunit	7720853	Purification of the hepatic glycogen-associated form of protein phosphatase-1 by microcystin-Sepharose affinity chromatography.

Q9C0L9	SEY1_CANAL	Protein SEY1	12076781	Characterization of the CaNAG3, CaNAG4, and CaNAG6 genes of the pathogenic fungus Candida albicans: possible involvement of these genes in the susceptibilities of cytotoxic agents.

O88845	AKA10_MOUSE	A-kinase anchor protein 10, mitochondrial	11248059	Cloning and mitochondrial localization of full-length D-AKAP2, a protein kinase A anchoring protein.

Q03654	CEF1_YEAST	Pre-mRNA-splicing factor CEF1	10092627	Cef1p is a component of the Prp19p-associated complex and essential for pre-mRNA splicing.

Q9W7E7	SMAD5_DANRE	Mothers against decapentaplegic homolog 5	10590480	Smad1 and smad5 have distinct roles during dorsoventral patterning of the zebrafish embryo.

P20606	SAR1_YEAST	Small COPII coat GTPase SAR1	9756629	Activities of mutant Sar1 proteins in guanine nucleotide binding, GTP hydrolysis, and cell-free transport from the endoplasmic reticulum to the Golgi apparatus.

P49788	TIG1_HUMAN	Retinoic acid receptor responder protein 1	8601727	Tazarotene-induced gene 1 (TIG1), a novel retinoic acid receptor- responsive gene in skin.

Q13761	RUNX3_HUMAN	Runt-related transcription factor 3	7607690	Identification of a new murine runt domain-containing gene, Cbfa3, and localization of the human homolog, CBFA3, to chromosome 1p35- pter.

P87108	TIM10_YEAST	Mitochondrial import inner membrane translocase subunit TIM10	9430585	Import of mitochondrial carriers mediated by essential proteins of the intermembrane space.

Q9NY99	SNTG2_HUMAN	Gamma-2-syntrophin	10747910	Gamma1- and gamma2-syntrophins, two novel dystrophin-binding proteins localized in neuronal cells.

Q8S8P5	WRK33_ARATH	Probable WRKY transcription factor 33	15990873	The MAP kinase substrate MKS1 is a regulator of plant defense responses.

Q9VVF7	MIP_DROME	Allatostatins MIP	11181081	Molecular cloning, genomic organization, and expression of a B-type (cricket-type) allatostatin preprohormone from Drosophila melanogaster.

Q8CDJ3	BAKOR_MOUSE	Beclin 1-associated autophagy-related key regulator	19270696	Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages.

P09382	LEG1_HUMAN	Galectin-1	12761501	Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.

Q9USX3	RAD60_SCHPO	DNA repair protein rad60	12897162	Replication checkpoint kinase Cds1 regulates recombinational repair protein Rad60.

P51532	SMCA4_HUMAN	Transcription activator BRG1	8232556	BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription.

Q9W2B1	GR58B_DROME	Putative gustatory receptor 58b	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

P55884	EIF3B_HUMAN	Eukaryotic translation initiation factor 3 subunit B	14688252	The j-subunit of human translation initiation factor eIF3 is required for the stable binding of eIF3 and its subcomplexes to 40 S ribosomal subunits in vitro.

Q12208	YL132_YEAST	Uncharacterized protein YLR132C	14690591	Assigning function to yeast proteins by integration of technologies.

Q15042	RB3GP_HUMAN	Rab3 GTPase-activating protein catalytic subunit	9852129	Localization of the Rab3 small G protein regulators in nerve terminals and their involvement in Ca2+-dependent exocytosis.

Q8WTW3	COG1_HUMAN	Conserved oligomeric Golgi complex subunit 1	11980916	Characterization of a mammalian Golgi-localized protein complex, COG, that is required for normal Golgi morphology and function.

P32053	INTA_ECOLI	Prophage CP4-57 integrase	7511583	Excision of a P4-like cryptic prophage leads to Alp protease expression in Escherichia coli.

Q02948	VPS30_YEAST	Vacuolar protein sorting-associated protein 30	9712845	Apg14p and Apg6/Vps30p form a protein complex essential for autophagy in the yeast, Saccharomyces cerevisiae.

Q9FE25	MYB75_ARATH	Transcription factor MYB75	16299184	Sucrose-specific induction of anthocyanin biosynthesis in Arabidopsis requires the MYB75/PAP1 gene.

Q9LZ03	TOP6A_ARATH	DNA topoisomerase 6 subunit A	16339310	RHL1 is an essential component of the plant DNA topoisomerase VI complex and is required for ploidy-dependent cell growth.

P18410	SPO7_YEAST	Sporulation-specific protein SPO7	9822591	A novel complex of membrane proteins required for formation of a spherical nucleus.

P35365	5HT5B_RAT	5-hydroxytryptamine receptor 5B	8224165	Cloning and characterization of the rat 5-HT5B receptor. Evidence that the 5-HT5B receptor couples to a G protein in mammalian cell membranes.

Q10746	CXCL3_RAT	C-X-C motif chemokine 3	9576061	Gene structure, cDNA cloning, and expression of the rat cytokine- induced neutrophil chemoattractant-2 (CINC-2) gene.

P56279	TCL1A_HUMAN	T-cell leukemia/lymphoma protein 1A	7809072	Identification of the TCL1 gene involved in T-cell malignancies.

O59776	YCCC_SCHPO	Uncharacterized protein C1795.12c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P60211	KA181_TITCA	Potassium channel toxin alpha-KTx 18.1	15025998	Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

O82799	NGA1_ARATH	B3 domain-containing transcription factor NGA1	16603651	Endogenous and synthetic microRNAs stimulate simultaneous, efficient, and localized regulation of multiple targets in diverse species.

Q03218	MMT1_YEAST	Mitochondrial metal transporter 1	9353309	Characterization of two homologous yeast genes that encode mitochondrial iron transporters.

Q923S6	NEU1A_MOUSE	Neuralized-like protein 1A	11585928	Isolation of a murine homologue of the Drosophila neuralized gene, a gene required for axonemal integrity in spermatozoa and terminal maturation of the mammary gland.

P37296	STV1_YEAST	V-type proton ATPase subunit a, Golgi isoform	11278748	Yeast V-ATPase complexes containing different isoforms of the 100-kDa a-subunit differ in coupling efficiency and in vivo dissociation.

P39014	MET30_YEAST	F-box protein MET30	10637232	Feedback-regulated degradation of the transcriptional activator Met4 is triggered by the SCF(Met30) complex.

Q01955	CO4A3_HUMAN	Collagen alpha-3(IV) chain	10837460	Two RGD-independent alpha vbeta 3 integrin binding sites on tumstatin regulate distinct anti-tumor properties.

P22725	WNT5A_MOUSE	Protein Wnt-5a	16602827	Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context.

P43657	LPAR6_HUMAN	Lysophosphatidic acid receptor 6	18297070	G protein-coupled receptor P2Y5 and its ligand LPA are involved in maintenance of human hair growth.

Q63524	TMED2_RAT	Transmembrane emp24 domain-containing protein 2	8663407	Tmp21 and p24A, two type I proteins enriched in pancreatic microsomal membranes, are members of a protein family involved in vesicular trafficking.

Q62871	DC1I2_RAT	Cytoplasmic dynein 1 intermediate chain 2	8522607	Cytoplasmic dynein binds dynactin through a direct interaction between the intermediate chains and p150Glued.

Q9BXM7	PINK1_HUMAN	Serine/threonine-protein kinase PINK1, mitochondrial	15087508	Hereditary early-onset Parkinson's disease caused by mutations in PINK1.

O49326	NSP2_ARATH	Nitrile-specifier protein 2	18987211	The genetic basis of constitutive and herbivore-induced ESP- independent nitrile formation in Arabidopsis.

P21374	ISY1_YEAST	Pre-mRNA-splicing factor ISY1	11842115	Functional and physical interactions between components of the Prp19p-associated complex.

P27884	CAC1A_RABIT	Voltage-dependent P/Q-type calcium channel subunit alpha-1A	1849233	Primary structure and functional expression from complementary DNA of a brain calcium channel.

Q9UQR0	SCML2_HUMAN	Sex comb on midleg-like protein 2	10331946	Identification of SCML2, a second human gene homologous to the Drosophila Sex comb on midleg (Scm): a new gene cluster on Xp22.

P39304	ULAD_ECOLI	3-keto-L-gulonate-6-phosphate decarboxylase ulaD	11900527	Homologous (beta/alpha)8-barrel enzymes that catalyze unrelated reactions: orotidine 5'-monophosphate decarboxylase and 3-keto-L- gulonate 6-phosphate decarboxylase.

Q9MA98	ERCC1_ARATH	DNA excision repair protein ERCC-1	15255863	Roles of the AtErcc1 protein in recombination.

Q12017	PLP2_YEAST	Phosducin-like protein 2	10749875	Functional analysis of Plp1 and Plp2, two homologues of phosducin in yeast.

P38894	FLO5_YEAST	Flocculation protein FLO5	9483793	Distribution of the flocculation protein, flop, at the cell surface during yeast growth: the availability of flop determines the flocculation level.

Q9BUL9	RPP25_HUMAN	Ribonuclease P protein subunit p25	15096576	Mutual interactions between subunits of the human RNase MRP ribonucleoprotein complex.

Q9SAH8	NRAM1_ARATH	Metal transporter Nramp1	10769179	Involvement of NRAMP1 from Arabidopsis thaliana in iron transport.

P69380	FIEF_ECOLI	Ferrous-iron efflux pump fieF	15549269	FieF (YiiP) from Escherichia coli mediates decreased cellular accumulation of iron and relieves iron stress.

P18206	VINC_HUMAN	Vinculin	15070891	Structural basis for amplifying vinculin activation by talin.

P80957	BDEF_TACTR	Big defensin	8282718	Separation of large and small granules from horseshoe crab (Tachypleus tridentatus) hemocytes and characterization of their components.

Q14160	SCRIB_HUMAN	Protein scribble homolog	16137684	The tumor suppressor Scrib selectively interacts with specific members of the zyxin family of proteins.

P40185	MMF1_YEAST	Protein MMF1, mitochondrial	11442631	A member of the YER057c/yjgf/Uk114 family links isoleucine biosynthesis and intact mitochondria maintenance in Saccharomyces cerevisiae.

B3DMA2	ACD11_RAT	Acyl-CoA dehydrogenase family member 11	14561759	Proteomic analysis of rat liver peroxisome: presence of peroxisome- specific isozyme of Lon protease.

Q9UQ88	CD11A_HUMAN	Cell division protein kinase 11A	8195233	Molecular cloning and expression of alternatively spliced PITSLRE protein kinase isoforms.

P41800	MMM1_YEAST	Maintenance of mitochondrial morphology protein 1	19556461	An ER-mitochondria tethering complex revealed by a synthetic biology screen.

O15119	TBX3_HUMAN	T-box transcription factor TBX3	10468588	Transcription repression by Xenopus ET and its human ortholog TBX3, a gene involved in ulnar-mammary syndrome.

P18670	LECA_ARTIN	Agglutinin alpha chain	8431469	Identification of a novel 4 kDa immunoglobulin-A-binding peptide obtained by the limited proteolysis of jacalin.

O00408	PDE2A_HUMAN	cGMP-dependent 3',5'-cyclic phosphodiesterase	9210593	Isolation and characterization of human cDNAs encoding a cGMP- stimulated 3',5'-cyclic nucleotide phosphodiesterase.

Q9NXR7	BRE_HUMAN	BRCA1-A complex subunit BRE	7826398	Identification of a brain- and reproductive-organs-specific gene responsive to DNA damage and retinoic acid.

P53632	PAP2_YEAST	Poly(A) RNA polymerase protein 2	15145828	Nuclear surveillance and degradation of hypomodified initiator tRNAMet in S. cerevisiae.

Q13507	TRPC3_HUMAN	Short transient receptor potential channel 3	9930701	Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol.

Q64562	CP21A_RAT	Steroid 21-hydroxylase	9408081	Cloning of two alternatively spliced 21-hydroxylase cDNAs from rat adrenal.

Q9VMA7	TGO1_DROME	Transport and Golgi organization protein 1	16452979	Functional genomics reveals genes involved in protein secretion and Golgi organization.

P63020	NFUA_ECOLI	Fe/S biogenesis protein nfuA	18339628	NfuA, a new factor required for maturing Fe/S proteins in Escherichia coli under oxidative stress and iron starvation conditions.

Q9Y2Q1	ZN257_HUMAN	Zinc finger protein 257	10585455	Molecular cloning of six novel Kruppel-like zinc finger genes from hematopoietic cells and identification of a novel transregulatory domain KRNB.

Q91YI4	ARRB2_MOUSE	Beta-arrestin-2	16051150	An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior.

P18206	VINC_HUMAN	Vinculin	14702644	Vinculin activation by talin through helical bundle conversion.

Q9VIF5	DEL_DROME	Protein deadlock	16616913	Deadlock, a novel protein of Drosophila, is required for germline maintenance, fusome morphogenesis and axial patterning in oogenesis and associates with centrosomes in the early embryo.

Q8VHS2	CRUM1_MOUSE	Crumbs homolog 1	12915475	CRB1 is essential for external limiting membrane integrity and photoreceptor morphogenesis in the mammalian retina.

Q9Z0U5	ADO_RAT	Aldehyde oxidase	9920943	cDNA cloning, sequencing, and characterization of male and female rat liver aldehyde oxidase (rAOX1). Differences in redox status may distinguish male and female forms of hepatic APX.

P14866	HNRPL_HUMAN	Heterogeneous nuclear ribonucleoprotein L	2687284	A novel heterogeneous nuclear RNP protein with a unique distribution on nascent transcripts.

P33241	LSP1_HUMAN	Lymphocyte-specific protein 1	8274738	The 47-kD protein increased in neutrophil actin dysfunction with 47- and 89-kD protein abnormalities is lymphocyte-specific protein.

Q8RXN0	AB11G_ARATH	ABC transporter G family member 11	17727615	Characterization of Arabidopsis ABCG11/WBC11, an ATP binding cassette (ABC) transporter that is required for cuticular lipid secretion.

P84677	SC29_TITCA	Toxin Tc29	15025998	Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

Q563C3	CCA5A_XENLA	Sororin	15837422	Sororin, a substrate of the anaphase-promoting complex, is required for sister chromatid cohesion in vertebrates.

Q811W0	SOX21_MOUSE	Transcription factor SOX-21	12446692	Mouse mu opioid receptor distal promoter transcriptional regulation by SOX proteins.

P29539	RIF1_YEAST	Telomere length regulator protein RIF1	1577274	A RAP1-interacting protein involved in transcriptional silencing and telomere length regulation.

Q08162	RRP44_YEAST	Exosome complex exonuclease DIS3	17173052	A single subunit, Dis3, is essentially responsible for yeast exosome core activity.

Q91X83	METK1_MOUSE	S-adenosylmethionine synthase isoform type-1	8314764	Cloning and expression of murine S-adenosylmethionine synthetase.

Q61598	GDIB_MOUSE	Rab GDP dissociation inhibitor beta	7782346	Two-hybrid system screen with the small GTP-binding protein Rab6. Identification of a novel mouse GDP dissociation inhibitor isoform and two other potential partners of Rab6.

Q96GR2	ACBG1_HUMAN	Long-chain-fatty-acid--CoA ligase ACSBG1	10954726	Very long-chain acyl-CoA synthetases. Human 'bubblegum' represents a new family of proteins capable of activating very long-chain fatty acids.

Q5EAK6	ATM_DROME	Serine/threonine-protein kinase ATM	15296752	The Drosophila ATM ortholog, dATM, mediates the response to ionizing radiation and to spontaneous DNA damage during development.

P68032	ACTC_HUMAN	Actin, alpha cardiac muscle 1	17947298	Alpha-cardiac actin mutations produce atrial septal defects.

P38803	IPI1_YEAST	Pre-rRNA-processing protein IPI1	15528184	Rea1, a dynein-related nuclear AAA-ATPase, is involved in late rRNA processing and nuclear export of 60 S subunits.

Q9USY8	YBPF_SCHPO	Uncharacterized protein C16H5.15	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9JHW9	AL1A3_MOUSE	Aldehyde dehydrogenase family 1 member A3	11013254	Aldehyde dehydrogenase 6, a cytosolic retinaldehyde dehydrogenase prominently expressed in sensory neuroepithelia during development.

Q9SB04	ARR5_ARATH	Two-component response regulator ARR5	14973166	Type-A Arabidopsis response regulators are partially redundant negative regulators of cytokinin signaling.

P40992	RRN7_YEAST	RNA polymerase I-specific transcription initiation factor RRN7	8702872	RRN11 encodes the third subunit of the complex containing Rrn6p and Rrn7p that is essential for the initiation of rDNA transcription by yeast RNA polymerase I.

Q9UBM1	PEMT_HUMAN	Phosphatidylethanolamine N-methyltransferase	9989271	Identification of three novel cDNAs for human phosphatidylethanolamine N-methyltransferase and localization of the human gene on chromosome 17p11.2.

P29414	CXA3_RAT	Gap junction alpha-3 protein	1659572	Connexin46, a novel lens gap junction protein, induces voltage-gated currents in nonjunctional plasma membrane of Xenopus oocytes.

P38077	ATPG_YEAST	ATP synthase subunit gamma, mitochondrial	17082766	Novel features of the rotary catalytic mechanism revealed in the structure of yeast F1 ATPase.

Q9GYV5	NEMO_DROME	NF-kappa-B essential modulator	11018014	A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity.

Q12311	NTO1_YEAST	NuA3 HAT complex component NTO1	14562095	Global analysis of protein localization in budding yeast.

O14019	HAL4_SCHPO	Serine/threonine-protein kinase hal4	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q91XE4	ACY3_MOUSE	Aspartoacylase-2	14656720	Structural characterization, tissue distribution, and functional expression of murine aminoacylase III.

P22265	TSH_DROME	Protein teashirt	11429289	Identification of a regulatory allele of teashirt (tsh) in Drosophila melanogaster that affects wing hinge development. An adult-specific tsh enhancer in Drosophila.

O94451	PLI1_SCHPO	E3 SUMO-protein ligase pli1	15359282	Role of the fission yeast SUMO E3 ligase Pli1p in centromere and telomere maintenance.

P45984	MK09_HUMAN	Mitogen-activated protein kinase 9	7969172	Signal transduction by tumor necrosis factor mediated by JNK protein kinases.

P31785	IL2RG_HUMAN	Cytokine receptor common subunit gamma	8266076	Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4.

O15527	OGG1_HUMAN	N-glycosylase/DNA lyase	9190902	Cloning of a human homolog of the yeast OGG1 gene that is involved in the repair of oxidative DNA damage.

Q9WUP0	RAMP2_MOUSE	Receptor activity-modifying protein 2	10854696	Mouse receptor-activity-modifying proteins 1, -2 and -3: amino acid sequence, expression and function.

P31749	AKT1_HUMAN	RAC-alpha serine/threonine-protein kinase	19713527	The E3 ligase TRAF6 regulates Akt ubiquitination and activation.

Q9QXN5	MIOX_MOUSE	Inositol oxygenase	10944187	Identification of a renal-specific oxido-reductase in newborn diabetic mice.

P38801	LRP1_YEAST	Exosome complex protein LRP1	12837249	A panoramic view of yeast noncoding RNA processing.

Q47013	ELAD_ECOLI	Protease elaD	17440617	ElaD, a deubiquitinating protease expressed by E. coli.

P30968	GNRHR_HUMAN	Gonadotropin-releasing hormone receptor	8386108	Cloning and characterization of the human GnRH receptor.

O88828	RPAB2_RAT	DNA-directed RNA polymerases I, II, and III subunit RPABC2	10393248	A serine residue in the N-terminal acidic region of rat RPB6, one of the common subunits of RNA polymerases, is exclusively phosphorylated by casein kinase II in vitro.

O00835	ERCC3_DICDI	TFIIH basal transcription factor complex helicase repB subunit	9649625	Rapid changes of nucleotide excision repair gene expression following UV-irradiation and cisplatin treatment of Dictyostelium discoideum.

Q9FFC0	H2B10_ARATH	Histone H2B.10	17242155	VIM1, a methylcytosine-binding protein required for centromeric heterochromatinization.

Q9BYC5	FUT8_HUMAN	Alpha-(1,6)-fucosyltransferase	9133635	Purification and cDNA cloning of GDP-L-Fuc:N-acetyl-beta-D- glucosaminide:alpha1-6 fucosyltransferase (alpha1-6 FucT) from human gastric cancer MKN45 cells.

Q90X64	VNG2A_XENLA	Vang-like protein 2-A	12421719	Neural tube closure requires Dishevelled-dependent convergent extension of the midline.

P87110	ITR2_SCHPO	Myo-inositol transporter 2	9560432	Exogenous inositol and genes responsible for inositol transport are required for mating and sporulation in Shizosaccharomyces pombe.

Q7Q2B7	CARM1_ANOGA	Histone-arginine methyltransferase CARMER	19472346	Delineating Anopheles gambiae coactivator associated arginine methyltransferase 1 automethylation using top-down high resolution tandem mass spectrometry.

P26770	ADCY4_RAT	Adenylate cyclase type 4	1946437	Cloning and expression of a widely distributed (type IV) adenylyl cyclase.

Q9ZTP3	EIN4_ARATH	Protein EIN4	9707532	EIN4 and ERS2 are members of the putative ethylene receptor gene family in Arabidopsis.

Q02779	M3K10_HUMAN	Mitogen-activated protein kinase kinase kinase 10	8536694	Complete nucleotide sequence, expression, and chromosomal localisation of human mixed-lineage kinase 2.

P06760	BGLR_RAT	Beta-glucuronidase	3355537	Rat liver beta-glucuronidase. cDNA cloning, sequence comparisons and expression of a chimeric protein in COS cells.

Q9LD43	ACCA_ARATH	Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, chloroplastic	12766230	Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.

Q64HC7	ARMAD_ARMVU	Armadillidin	15752546	Armadillidin: a novel glycine-rich antibacterial peptide directed against Gram-positive bacteria in the woodlouse Armadillidium vulgare (terrestrial isopod, crustacean).

P78549	NTHL1_HUMAN	Endonuclease III-like protein 1	9831664	Genomic structure and sequence of a human homologue (NTHL1/NTH1) of Escherichia coli endonuclease III with those of the adjacent parts of TSC2 and SLC9A3R2 genes.

Q6AZB0	BOC_MOUSE	Brother of CDO	11782431	BOC, an Ig superfamily member, associates with CDO to positively regulate myogenic differentiation.

Q99932	SPAG8_HUMAN	Sperm-associated antigen 8	8788182	Expression and characterization of a novel human sperm membrane protein.

Q91WC3	ACSL6_MOUSE	Long-chain-fatty-acid--CoA ligase 6	12767919	A novel murine long-chain acyl-CoA synthetase expressed in brain participates in neuronal cell proliferation.

Q9NZD2	GLTP_HUMAN	Glycolipid transfer protein	15287756	Human glycolipid transfer protein: probing conformation using fluorescence spectroscopy.

P23497	SP100_HUMAN	Nuclear autoantigen Sp-100	9973607	Splice variants of the nuclear dot-associated Sp100 protein contain homologies to HMG-1 and a human nuclear phosphoprotein-box motif.

Q9I9P9	SMAD2_DANRE	Mothers against decapentaplegic homolog 2	10767528	Cloning and characterization of zebrafish smad2, smad3 and smad4.

Q5AVS0	XLNR_EMENI	Xylanolytic transcriptional activator xlnR	18420433	CreA mediates repression of the regulatory gene xlnR which controls the production of xylanolytic enzymes in Aspergillus nidulans.

P55287	CAD11_HUMAN	Cadherin-11	8163513	Molecular cloning and characterization of OB-cadherin, a new member of cadherin family expressed in osteoblasts.

P21825	SEC62_YEAST	Translocation protein SEC62	12518317	Identification of novel protein-protein interactions at the cytosolic surface of the Sec63 complex in the yeast ER membrane.

Q6Z7V2	HS24M_ORYSJ	24.1 kDa heat shock protein, mitochondrial	19703271	Rice sHsp genes: genomic organization and expression profiling under stress and development.

Q24472	RBF_DROME	Retinoblastoma family protein	15479636	Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes.

O18330	MRJP1_APIME	Major royal jelly protein 1	15203237	Jelleines: a family of antimicrobial peptides from the royal jelly of honeybees (Apis mellifera).

P33313	CNS1_YEAST	Hsp70/Hsp90 co-chaperone CNS1	12788914	Functional interactions between Hsp90 and the co-chaperones Cns1 and Cpr7 in Saccharomyces cerevisiae.

O14829	PPE1_HUMAN	Serine/threonine-protein phosphatase with EF-hands 1	9215685	A novel human serine-threonine phosphatase related to the Drosophila retinal degeneration C (rdgC) gene is selectively expressed in sensory neurons of neural crest origin.

Q03626	MUG1_RAT	Murinoglobulin-1	1709877	Differential regulation of the two mRNA species of the rodent negative acute phase protein alpha 1-inhibitor 3.

P41698	BUD8_YEAST	Bud site selection protein 8	11514631	Bud8p and Bud9p, proteins that may mark the sites for bipolar budding in yeast.

P40525	RL34B_YEAST	60S ribosomal protein L34-B	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q9GZL7	WDR12_HUMAN	Ribosome biogenesis protein WDR12	16738141	Dominant-negative Pes1 mutants inhibit ribosomal RNA processing and cell proliferation via incorporation into the PeBoW-complex.

Q10430	SPC25_SCHPO	Kinetochore protein spc25	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q68E01	INT3_HUMAN	Integrator complex subunit 3	19683501	SOSS complexes participate in the maintenance of genomic stability.

O07621	HEMAT_BACSU	Heme-based aerotactic transducer hemAT	10676961	Myoglobin-like aerotaxis transducers in Archaea and Bacteria.

O94647	PPK24_SCHPO	Serine/threonine-protein kinase ppk24, mitochondrial	15821139	Systematic deletion analysis of fission yeast protein kinases.

O76324	DCO_DROME	Discs overgrown protein kinase	9674431	The Drosophila clock gene double-time encodes a protein closely related to human casein kinase I epsilon.

Q1JQ73	ELV1A_XENLA	ELAV-like protein 1-A	13679363	Xenopus cold-inducible RNA-binding protein 2 interacts with ElrA, the Xenopus homolog of HuR, and inhibits deadenylation of specific mRNAs.

O42478	TLE4_XENLA	Transducin-like enhancer protein 4	16586348	Bowline, a novel protein localized to the presomitic mesoderm, interacts with Groucho/TLE in Xenopus.

P38249	EIF3A_YEAST	Eukaryotic translation initiation factor 3 subunit A	9671501	Identification of a translation initiation factor 3 (eIF3) core complex, conserved in yeast and mammals, that interacts with eIF5.

Q9STV4	CIPK8_ARATH	CBL-interacting serine/threonine-protein kinase 8	12029080	Biochemical and functional characterization of PKS11, a novel Arabidopsis protein kinase.

Q14676	MDC1_HUMAN	Mediator of DNA damage checkpoint protein 1	12607005	MDC1 is a mediator of the mammalian DNA damage checkpoint.

Q9UQB3	CTND2_HUMAN	Catenin delta-2	19706687	PDZ-domain-directed basolateral targeting of the peripheral membrane protein FRMPD2 in epithelial cells.

P32789	ALK2_YEAST	Serine/threonine-protein kinase Haspin homolog ALK2	16855400	Alk1 and Alk2 are two new cell cycle-regulated haspin-like proteins in budding yeast.

P68133	ACTS_HUMAN	Actin, alpha skeletal muscle	11333380	Nemaline myopathy caused by mutations in the muscle alpha-skeletal- actin gene.

P54317	LIPR2_HUMAN	Pancreatic lipase-related protein 2	1379598	Two novel human pancreatic lipase related proteins, hPLRP1 and hPLRP2. Differences in colipase dependence and in lipase activity.

O60130	YH7G_SCHPO	Putative transcriptional regulatory protein C16G5.16	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NS23	RASF1_HUMAN	Ras association domain-containing protein 1	14743218	The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex.

Q8LCE1	GLN12_ARATH	Glutamine synthetase cytosolic isozyme 1-2	14757761	Kinetic properties and ammonium-dependent regulation of cytosolic isoenzymes of glutamine synthetase in Arabidopsis.

Q9XZL8	SRA_DROME	Protein sarah	15611177	Expression level of sarah, a homolog of DSCR1, is critical for ovulation and female courtship behavior in Drosophila melanogaster.

P00425	COX5B_YEAST	Cytochrome c oxidase polypeptide 5B, mitochondrial	2986105	Two nonidentical forms of subunit V are functional in yeast cytochrome c oxidase.

P07271	PIF1_YEAST	DNA repair and recombination protein PIF1	8253734	PIF1 DNA helicase from Saccharomyces cerevisiae. Biochemical characterization of the enzyme.

O74252	STE12_EMENI	Transcription factor steA	10792717	Aspergillus SteA (Sterile12-like) is a homeodomain-C2/H2-Zn+2 finger transcription factor required for sexual reproduction.

P15700	UMPK_YEAST	Uridylate kinase	1333436	The adenylate kinase family in yeast: identification of URA6 as a multicopy suppressor of deficiency in major AMP kinase.

P53705	BUD4_CANAL	Bud site selection protein BUD4	11694587	Candida albicans Int1p interacts with the septin ring in yeast and hyphal cells.

P41052	MLTB_ECOLI	Membrane-bound lytic murein transglycosylase B	7476170	Cloning and expression of a murein hydrolase lipoprotein from Escherichia coli.

Q63799	TCEA2_RAT	Transcription elongation factor A protein 2	8300645	Cloning and identification of testis-specific transcription elongation factor S-II.

P04002	ANPA_PSEAM	Ice-structuring protein A	3769927	Biosynthesis of antifreeze polypeptides in the winter flounder. Characterization and seasonal occurrence of precursor polypeptides.

O64948	LONP2_ARATH	Lon protease homolog 2, peroxisomal	19329564	In-depth proteome analysis of Arabidopsis leaf peroxisomes combined with in vivo subcellular targeting verification indicates novel metabolic and regulatory functions of peroxisomes.

Q9ZNV9	AHP1_ARATH	Histidine-containing phosphotransfer protein 1	12068096	Two-component signal transduction pathways in Arabidopsis.

O14980	XPO1_HUMAN	Exportin-1	9368044	Molecular cloning and cell cycle-dependent expression of mammalian CRM1, a protein involved in nuclear export of proteins.

Q9XZT7	TAFAB_DROME	Transcription initiation factor TFIID subunit 10b	10669741	Two novel Drosophila TAFIIs have homology with human TAFII30 and are differentially regulated during development.

Q9NPC4	A4GAT_HUMAN	Lactosylceramide 4-alpha-galactosyltransferase	10748143	Molecular cloning of globotriaosylceramide/CD77 synthase, a glycosyltransferase that initiates the synthesis of globo series glycosphingolipids.

Q60520	SIN3A_MOUSE	Paired amphipathic helix protein Sin3a	12130660	Tissue-specific regulation of retinal and pituitary precursor cell proliferation.

O74967	VPS25_SCHPO	Vacuolar protein-sorting-associated protein 25	17660439	Essential roles of class E Vps proteins for sorting into multivesicular bodies in Schizosaccharomyces pombe.

O60711	LPXN_HUMAN	Leupaxin	9565592	Leupaxin is a novel LIM domain protein that forms a complex with PYK2.

Q9UHF5	IL17B_HUMAN	Interleukin-17B	10639155	Cloning and characterization of IL-17B and IL-17C, two new members of the IL-17 cytokine family.

Q8K348	ACV1C_MOUSE	Activin receptor type-1C	15485907	ALK7, a receptor for nodal, is dispensable for embryogenesis and left-right patterning in the mouse.

P40509	COPE_YEAST	Coatomer subunit epsilon	9463377	Epsilon-COP is a structural component of coatomer that functions to stabilize alpha-COP.

Q8AV13	ANM1A_XENLA	Protein arginine N-methyltransferase 1-A	17074753	RAP55, a cytoplasmic mRNP component, represses translation in Xenopus oocytes.

Q9R1B9	SLIT2_MOUSE	Slit homolog 2 protein	11804571	Slit proteins prevent midline crossing and determine the dorsoventral position of major axonal pathways in the mammalian forebrain.

Q14103	HNRPD_HUMAN	Heterogeneous nuclear ribonucleoprotein D0	12674497	Identification and characterization of proteins that selectively interact with isoforms of the mRNA binding protein AUF1 (hnRNP D).

P53848	FOL1_YEAST	Folic acid synthesis protein FOL1	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P61212	ARL1_RAT	ADP-ribosylation factor-like protein 1	11792819	Regulation of Golgi structure and function by ARF-like protein 1 (Arl1).

Q552S0	NHE1_DICDI	Sodium/hydrogen exchanger 1	15851518	A developmentally regulated Na-H exchanger in Dictyostelium discoideum is necessary for cell polarity during chemotaxis.

Q9SR43	PFBS_ARATH	Phytochromobilin:ferredoxin oxidoreductase, chloroplastic	11226195	The Arabidopsis HY2 gene encodes phytochromobilin synthase, a ferredoxin-dependent biliverdin reductase.

Q12246	LCB4_YEAST	Sphingoid long chain base kinase 4	16141212	Regulation of the sphingoid long-chain base kinase Lcb4p by ergosterol and heme: studies in phytosphingosine-resistant mutants.

P25623	SYP1_YEAST	Suppressor of yeast profilin deletion	11014808	Suppression of the profilin-deficient phenotype by the RHO2 signaling pathway in Saccharomyces cerevisiae.

P79222	CALCR_RABIT	Calcitonin receptor	8940110	The deletion of 14 amino acids in the seventh transmembrane domain of a naturally occurring calcitonin receptor isoform alters ligand binding and selectively abolishes coupling to phospholipase C.

O94683	RRP7_SCHPO	Ribosomal RNA-processing protein 7	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O22207	UBP5_ARATH	Ubiquitin carboxyl-terminal hydrolase 5	10898935	Ubiquitin-specific proteases from Arabidopsis thaliana: cloning of AtUBP5 and analysis of substrate specificity of AtUBP3, AtUBP4, and AtUBP5 using Escherichia coli in vivo and in vitro assays.

P11655	SEC12_YEAST	Guanine nucleotide-exchange factor SEC12	8377826	SEC12 encodes a guanine-nucleotide-exchange factor essential for transport vesicle budding from the ER.

Q54PQ4	GEFA_DICDI	Ras guanine nucleotide exchange factor A	8793298	The aimless RasGEF is required for processing of chemotactic signals through G-protein-coupled receptors in Dictyostelium.

Q7Z569	BRAP_HUMAN	BRCA1-associated protein	9497340	Identification of a novel cytoplasmic protein that specifically binds to nuclear localization signal motifs.

Q9Y3P9	RBGP1_HUMAN	Rab GTPase-activating protein 1	10202141	Characterization of GAPCenA, a GTPase activating protein for Rab6, part of which associates with the centrosome.

O14032	YEMB_SCHPO	UPF0664 stress-induced protein C29B12.11c	12529438	Global transcriptional responses of fission yeast to environmental stress.

O60136	YNS5_SCHPO	Uncharacterized WD repeat-containing protein C18H10.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9Y709	SKP1_SCHPO	Suppressor of kinetochore protein 1	15555586	Mcs2 and a novel CAK subunit Pmh1 associate with Skp1 in fission yeast.

Q9NYB0	TE2IP_HUMAN	Telomeric repeat-binding factor 2-interacting protein 1	15383534	Telosome, a mammalian telomere-associated complex formed by multiple telomeric proteins.

Q5U349	UBP2_RAT	Ubiquitin carboxyl-terminal hydrolase 2	10938131	Divergent N-terminal sequences target an inducible testis deubiquitinating enzyme to distinct subcellular structures.

Q8I5G1	YPF10_PLAF7	Uncharacterized protein PFL1235c	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

Q20646	CEP1_CAEEL	Transcription factor cep-1	11557844	Caenorhabditis elegans p53: role in apoptosis, meiosis, and stress resistance.

P18776	DMSB_ECOLI	Anaerobic dimethyl sulfoxide reductase chain B	1653010	Alteration of the iron-sulfur cluster composition of Escherichia coli dimethyl sulfoxide reductase by site-directed mutagenesis.

O13795	POF8_SCHPO	Protein pof8	15147268	Molecular interactions of fission yeast Skp1 and its role in the DNA damage checkpoint.

P24626	CHI3_ORYSJ	Chitinase 3	18211919	Role of the loop structure of the catalytic domain in rice class I chitinase.

Q12265	KPR5_YEAST	Ribose-phosphate pyrophosphokinase 5	15280369	Heterooligomeric phosphoribosyl diphosphate synthase of Saccharomyces cerevisiae: combinatorial expression of the five PRS genes in Escherichia coli.

P40547	VID28_YEAST	Vacuolar import and degradation protein 28	14562095	Global analysis of protein localization in budding yeast.

P04209	LV211_HUMAN	Ig lambda chain V-II region NIG-84	3922791	Amino acid sequence of an amyloidogenic Bence Jones protein in myeloma-associated systemic amyloidosis.

Q96Q15	SMG1_HUMAN	Serine/threonine-protein kinase SMG1	11331269	Cloning of a novel phosphatidylinositol kinase-related kinase: characterization of the human SMG-1 RNA surveillance protein.

Q12289	CRC1_YEAST	Mitochondrial carnitine carrier	10545096	Molecular characterization of carnitine-dependent transport of acetyl-CoA from peroxisomes to mitochondria in Saccharomyces cerevisiae and identification of a plasma membrane carnitine transporter, Agp2p.

O76054	S14L2_HUMAN	SEC14-like protein 2	11444841	Tocopherol-associated protein is a ligand-dependent transcriptional activator.

P01824	HV206_HUMAN	Ig heavy chain V-II region WAH	6806818	Complete amino acid sequence of the delta heavy chain of human immunoglobulin D.

Q59MQ0	MYO5_CANAL	Myosin-5	12455956	Myosin I is required for hypha formation in Candida albicans.

Q08760	RAX1_YEAST	Bud site selection protein RAX1	15356260	Interactions among Rax1p, Rax2p, Bud8p, and Bud9p in marking cortical sites for bipolar bud-site selection in yeast.

Q12018	CDC53_YEAST	Cell division control protein 53	9346239	A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p.

Q24352	GBRAL_DROME	Gamma-aminobutyric acid receptor alpha-like	8189252	Sequence of a Drosophila ligand-gated ion-channel polypeptide with an unusual amino-terminal extracellular domain.

Q9VKH6	PPT2_DROME	Lysosomal thioesterase PPT2 homolog	18719403	The Drosophila protein palmitoylome: characterizing palmitoyl- thioesterases and DHHC palmitoyl-transferases.

P53108	YIP5_YEAST	Protein YIP5	17178117	Tvp38, Tvp23, Tvp18 and Tvp15: novel membrane proteins in the Tlg2- containing Golgi/endosome compartments of Saccharomyces cerevisiae.

Q9HGL4	TRM6_SCHPO	tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit trm6	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q10056	SHK2_SCHPO	Serine/threonine-protein kinase shk2	9660817	Cloning and characterization of shk2, a gene encoding a novel p21- activated protein kinase from fission yeast.

Q3KQ35	S17AA_XENLA	Transcription factor Sox-17-alpha-A	9363948	Xsox17alpha and -beta mediate endoderm formation in Xenopus.

P24071	FCAR_HUMAN	Immunoglobulin alpha Fc receptor	2258698	Expression cloning of a human Fc receptor for IgA.

O00291	HIP1_HUMAN	Huntingtin-interacting protein 1	11517213	HIP1 functions in clathrin-mediated endocytosis through binding to clathrin and adaptor protein 2.

P01189	COLI_HUMAN	Pro-opiomelanocortin	9620771	Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans.

Q9VET0	NPF_DROME	Neuropeptide F	10499420	Identification of a Drosophila brain-gut peptide related to the neuropeptide Y family.

P0A9L8	P5CR_ECOLI	Pyrroline-5-carboxylate reductase	6296787	Escherichia coli delta 1-pyrroline-5-carboxylate reductase: gene sequence, protein overproduction and purification.

Q8R000	OSTA_MOUSE	Organic solute transporter subunit alpha	17650074	Heterodimerization, trafficking and membrane topology of the two proteins, Ost alpha and Ost beta, that constitute the organic solute and steroid transporter.

Q6GUG4	P2Y13_RAT	P2Y purinoceptor 13	15183123	Cloning, pharmacological characterisation and distribution of the rat G-protein-coupled P2Y(13) receptor.

P43579	IES1_YEAST	Ino eighty subunit 1	14562095	Global analysis of protein localization in budding yeast.

Q62845	CNTN4_RAT	Contactin-4	8586965	Overlapping and differential expression of BIG-2, BIG-1, TAG-1, and F3: four members of an axon-associated cell adhesion molecule subgroup of the immunoglobulin superfamily.

Q8T0S6	HIPPO_DROME	Serine/threonine-protein kinase hippo	14502294	Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway.

P23500	MRS4_YEAST	Mitochondrial RNA-splicing protein MRS4	1703236	MRS3 and MRS4, two suppressors of mtRNA splicing defects in yeast, are new members of the mitochondrial carrier family.

P26006	ITA3_HUMAN	Integrin alpha-3	1655803	Molecular cloning and expression of the cDNA for alpha 3 subunit of human alpha 3 beta 1 (VLA-3), an integrin receptor for fibronectin, laminin, and collagen.

O94721	YCF9_SCHPO	RWD domain-containing protein C1393.09c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9VS38	MED4_DROME	Mediator of RNA polymerase II transcription subunit 4	11259581	Drosophila Mediator complex is broadly utilized by diverse gene- specific transcription factors at different types of core promoters.

Q06481	APLP2_HUMAN	Amyloid-like protein 2	8220435	Isolation and characterization of APLP2 encoding a homologue of the Alzheimer's associated amyloid beta protein precursor.

P49597	P2C56_ARATH	Protein phosphatase 2C 56	19407143	Regulators of PP2C phosphatase activity function as abscisic acid sensors.

Q43125	CRY1_ARATH	Cryptochrome-1	18003924	Separate functions for nuclear and cytoplasmic cryptochrome 1 during photomorphogenesis of Arabidopsis seedlings.

O35854	BCAT2_RAT	Branched-chain-amino-acid aminotransferase, mitochondrial	9165094	Cloning of the rat and human mitochondrial branched chain aminotransferases (BCATm).

P10408	SECA_ECOLI	Protein translocase subunit secA	17229438	Structure of dimeric SecA, the Escherichia coli preprotein translocase motor.

Q9UK97	FBX9_HUMAN	F-box only protein 9	10531035	Identification of a family of human F-box proteins.

Q84LH3	WEX_ARATH	Werner Syndrome-like exonuclease	11058127	Molecular characterisation of RecQ homologues in Arabidopsis thaliana.

P20264	PO3F3_HUMAN	POU domain, class 3, transcription factor 3	8703082	Class III POU genes: generation of homopolymeric amino acid repeats under GC pressure in mammals.

O42342	SOX7_XENLA	Transcription factor Sox-7	8950180	Cloning and characterization of Xenopus laevis xSox7 cDNA.

Q9GZQ8	MLP3B_HUMAN	Microtubule-associated proteins 1A/1B light chain 3B	15355958	Human light chain 3/MAP1LC3B is cleaved at its carboxyl-terminal Met121 to expose Gly120 for lipidation and targeting to autophagosomal membranes.

P43609	RSC8_YEAST	Chromatin structure-remodeling complex protein RSC8	10619019	Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains.

P80303	NUCB2_HUMAN	Nucleobindin-2	7811391	Human protein NEFA, a novel DNA binding/EF-hand/leucine zipper protein. Molecular cloning and sequence analysis of the cDNA, isolation and characterization of the protein.

P40034	JHD1_YEAST	JmjC domain-containing histone demethylation protein 1	16362057	Histone demethylation by a family of JmjC domain-containing proteins.

Q8MVR1	GBPC_DICDI	Cyclic GMP-binding protein C	16546177	Myosin light chain kinase A is activated by cGMP-dependent and cGMP- independent pathways.

Q55BY1	RSSA_DICDI	40S ribosomal protein SA	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P49427	UB2R1_HUMAN	Ubiquitin-conjugating enzyme E2 R1	20347421	Priming and extending: a UbcH5/Cdc34 E2 handoff mechanism for polyubiquitination on a SCF substrate.

Q9Y3R5	DOP2_HUMAN	Protein dopey-2	10950924	C21orf5, a novel human chromosome 21 gene, has a Caenorhabditis elegans ortholog (pad-1) required for embryonic patterning.

Q9NZU7	CABP1_HUMAN	Calcium-binding protein 1	15140941	Ca2+-binding protein-1 facilitates and forms a postsynaptic complex with Cav1.2 (L-type) Ca2+ channels.

Q8GFE2	CPLR_DESHA	Chlorophenol reductase	12697029	Purification, cloning and sequencing of an enzyme mediating the reductive dechlorination of 2,4,6-trichlorophenol from Desulfitobacterium frappieri PCP-1.

P11140	ABRA_ABRPR	Abrin-a	2016300	Direct molecular cloning and expression of two distinct abrin A- chains.

P57750	AGM1_ARATH	Phosphoacetylglucosamine mutase	8329681	Selection of Arabidopsis cDNAs that partially correct phenotypes of Escherichia coli DNA-damage-sensitive mutants and analysis of two plant cDNAs that appear to express UV-specific dark repair activities.

Q02410	APBA1_HUMAN	Amyloid beta A4 precursor protein-binding family A member 1	9614075	The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion.

P53628	SNF12_YEAST	Transcription regulatory protein SNF12	8804308	Essential role of Swp73p in the function of yeast Swi/Snf complex.

P49848	TAF6_HUMAN	Transcription initiation factor TFIID subunit 6	15601843	Core promoter binding by histone-like TAF complexes.

O95361	TRI16_HUMAN	Tripartite motif-containing protein 16	11919186	The estrogen-responsive B box protein: a novel regulator of keratinocyte differentiation.

Q7PYF4	GR24_ANOGA	Gustatory and odorant receptor 24	17167414	Two chemosensory receptors together mediate carbon dioxide detection in Drosophila.

Q8N8A2	ANR44_HUMAN	Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B	18186651	Protein phosphatase 6 regulatory subunits composed of ankyrin repeat domains.

P19328	ADA2B_RAT	Alpha-2B adrenergic receptor	2158103	Molecular characterization of a rat alpha 2B-adrenergic receptor.

Q9HAU4	SMUF2_HUMAN	E3 ubiquitin-protein ligase SMURF2	11016919	Smurf2 Is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling.

Q86K86	IPT_DICDI	Isopentenyl transferase	18216168	Cytokinins induce sporulation in Dictyostelium.

Q96DA6	TIM14_HUMAN	Mitochondrial import inner membrane translocase subunit TIM14	16055927	Mutation of DNAJC19, a human homologue of yeast inner mitochondrial membrane co-chaperones, causes DCMA syndrome, a novel autosomal recessive Barth syndrome-like condition.

Q12349	ATP14_YEAST	ATP synthase subunit H, mitochondrial	8702761	ATP synthase of yeast mitochondria. Isolation of the subunit h and disruption of the ATP14 gene.

P22855	MAN1_YEAST	Alpha-mannosidase	12723970	Free-oligosaccharide control in the yeast Saccharomyces cerevisiae: roles for peptide:N-glycanase (Png1p) and vacuolar mannosidase (Ams1p).

P00533	EGFR_HUMAN	Epidermal growth factor receptor	10805725	Class II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptors.

Q9LDI3	CIPKO_ARATH	CBL-interacting serine/threonine-protein kinase 24	10725382	The Arabidopsis thaliana SOS2 gene encodes a protein kinase that is required for salt tolerance.

P30048	PRDX3_HUMAN	Thioredoxin-dependent peroxide reductase, mitochondrial	12492477	Mixed lineage kinase LZK and antioxidant protein-1 activate NF-kappaB synergistically.

Q8N2W9	PIAS4_HUMAN	E3 SUMO-protein ligase PIAS4	11388671	A putative protein inhibitor of activated STAT (PIASy) interacts with p53 and inhibits p53-mediated transactivation but not apoptosis.

P18170	DEC12_DROME	Defective chorion-1 protein, FC106 isoform	3378704	Cloning and analysis of the dec-1 female-sterile locus, a gene required for proper assembly of the Drosophila eggshell.

P32558	SPT16_YEAST	FACT complex subunit SPT16	15082784	Structural features of nucleosomes reorganized by yeast FACT and its HMG box component, Nhp6.

Q9Y2A9	B3GN3_HUMAN	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3	10072769	Selection of cDNAs encoding putative type II membrane proteins on the cell surface from a human full-length cDNA bank.

P46897	ATHB7_ARATH	Homeobox-leucine zipper protein ATHB-7	16055682	Homeodomain leucine zipper class I genes in Arabidopsis. Expression patterns and phylogenetic relationships.

Q8R1N0	ZN830_MOUSE	Zinc finger protein 830	15988037	Impaired mitotic progression and preimplantation lethality in mice lacking OMCG1, a new evolutionarily conserved nuclear protein.

Q99661	KIF2C_HUMAN	Kinesin-like protein KIF2C	11092768	Human CENP-H multimers colocalize with CENP-A and CENP-C at active centromere-kinetochore complexes.

P0AGD7	SRP54_ECOLI	Signal recognition particle protein	1331806	The E. coli ffh gene is necessary for viability and efficient protein export.

Q9FML2	HDA6_ARATH	Histone deacetylase 6	12486004	HDA6, a putative histone deacetylase needed to enhance DNA methylation induced by double-stranded RNA.

P35189	TAF14_YEAST	Transcription initiation factor TFIID subunit 14	7995524	TFIIF-TAF-RNA polymerase II connection.

Q9FWR4	DHAR1_ARATH	Glutathione S-transferase DHAR1, mitochondrial	12954611	Molecular definition of the ascorbate-glutathione cycle in Arabidopsis mitochondria reveals dual targeting of antioxidant defenses in plants.

Q91VK4	ITM2C_MOUSE	Integral membrane protein 2C	10679242	Growth suppression of Escherichia coli by induction of expression of mammalian genes with transmembrane or ATPase domains.

P57055	DSCR6_HUMAN	Protein ripply3	10814524	Isolation of two novel genes, DSCR5 and DSCR6, from Down syndrome critical region on human chromosome 21q22.2.

Q9D312	K1C20_MOUSE	Keratin, type I cytoskeletal 20	12857878	Keratin 20 helps maintain intermediate filament organization in intestinal epithelia.

P19158	IRA2_YEAST	Inhibitory regulator protein IRA2	2164637	IRA2, a second gene of Saccharomyces cerevisiae that encodes a protein with a domain homologous to mammalian ras GTPase-activating protein.

P53220	TIM21_YEAST	Mitochondrial import inner membrane translocase subunit TIM21	15797382	Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17.

P83243	KA131_TITCA	Potassium channel toxin alpha-KTx 13.1	15025998	Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

P08651	NFIC_HUMAN	Nuclear factor 1 C-type	8710515	CTF5 -- a new transcriptional activator of the NFI/CTF family.

Q03405	UPAR_HUMAN	Urokinase plasminogen activator surface receptor	8049431	The structure of the urokinase-type plasminogen activator receptor gene.

P36583	PCK2_SCHPO	Protein kinase C-like 2	11102532	Schizosaccharomyces pombe rho2p GTPase regulates cell wall alpha- glucan biosynthesis through the protein kinase pck2p.

Q06124	PTN11_HUMAN	Tyrosine-protein phosphatase non-receptor type 11	1280823	Identification of a human src homology 2-containing protein-tyrosine- phosphatase: a putative homolog of Drosophila corkscrew.

O14618	CCS_HUMAN	Copper chaperone for superoxide dismutase	9726962	The copper chaperone CCS directly interacts with copper/zinc superoxide dismutase.

P0AEZ3	MIND_ECOLI	Septum site-determining protein minD	1836760	The MinD protein is a membrane ATPase required for the correct placement of the Escherichia coli division site.

Q12497	FMP16_YEAST	Protein FMP16, mitochondrial	14562095	Global analysis of protein localization in budding yeast.

P70182	PI51A_MOUSE	Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha	8798574	Cloning of cDNAs encoding two isoforms of 68-kDa type I phosphatidylinositol 4-phosphate 5-kinase.

Q95ST2	WLS_DROME	Protein wntless	16678095	Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells.

Q6VVB1	NHLC1_HUMAN	E3 ubiquitin-protein ligase NHLRC1	18070875	Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG).

P09110	THIK_HUMAN	3-ketoacyl-CoA thiolase, peroxisomal	1679347	Characterization of the gene encoding human peroxisomal 3-oxoacyl-CoA thiolase (ACAA). No large DNA rearrangement in a thiolase-deficient patient.

Q80TM9	NISCH_MOUSE	Nischarin	11121431	Nischarin, a novel protein that interacts with the integrin alpha5 subunit and inhibits cell migration.

Q9HGM6	YHW5_SCHPO	Putative transporter C543.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P40364	MPM1_YEAST	Mitochondrial peculiar membrane protein 1	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q9UHG3	PCYOX_HUMAN	Prenylcysteine oxidase 1	10585463	Cloning, expression, and cellular localization of a human prenylcysteine lyase.

Q9P0L0	VAPA_HUMAN	Vesicle-associated membrane protein-associated protein A	10523508	VAP-33 localizes to both an intracellular vesicle population and with occludin at the tight junction.

O95619	YETS4_HUMAN	YEATS domain-containing protein 4	9302258	Cloning of a novel transcription factor-like gene amplified in human glioma including astrocytoma grade I.

Q9VDW3	DMDB_DROME	Dystrophin, isoform B	17355978	A putative Src homology 3 domain binding motif but not the C-terminal dystrophin WW domain binding motif is required for dystroglycan function in cellular polarity in Drosophila.

O74975	PCY1_SCHPO	Probable choline-phosphate cytidylyltransferase	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O23051	KAO1_ARATH	Ent-kaurenoic acid oxidase 1	11172076	The CYP88A cytochrome P450, ent-kaurenoic acid oxidase, catalyzes three steps of the gibberellin biosynthesis pathway.

P87377	VEGTA_XENLA	T-box protein VegT-A	9012531	Xenopus VegT RNA is localized to the vegetal cortex during oogenesis and encodes a novel T-box transcription factor involved in mesodermal patterning.

P05422	DEM1_PHYSA	Dermorphin-1	7287299	Amino acid composition and sequence of dermorphin, a novel opiate- like peptide from the skin of Phyllomedusa sauvagei.

Q9H8X2	IPPK_HUMAN	Inositol-pentakisphosphate 2-kinase	12084730	The synthesis of inositol hexakisphosphate. Characterization of human inositol 1,3,4,5,6-pentakisphosphate 2-kinase.

Q04175	SXM1_YEAST	Importin beta SMX1	9412461	A nuclear import pathway for a protein involved in tRNA maturation.

O14297	YF1F_SCHPO	Uncharacterized protein C9E9.15	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O04019	PS6AB_ARATH	26S protease regulatory subunit 6A homolog B	17081979	Regulatory functions of nuclear hexokinase1 complex in glucose signaling.

Q8L9T5	ATL2_ARATH	RING-H2 finger protein ATL2	17722694	Identification of 118 Arabidopsis transcription factor and 30 ubiquitin-ligase genes responding to chitin, a plant-defense elicitor.

Q9PTT2	JELT_LEPLA	Jeltraxin	14596590	Jeltraxin, a frog egg jelly glycoprotein, has calcium-dependent lectin properties and is related to human serum pentraxins CRP and SAP.

Q90ZH7	SX18B_XENLA	Transcription factor Sox-18B	12062811	Expression and characterization of Xenopus laevis SRY-related cDNAs, xSox17alpha1, xSox17alpha2, xSox18alpha and xSox18beta.

P26255	ADRB3_RAT	Beta-3 adrenergic receptor	1684635	Molecular cloning and expression of the rat beta 3-adrenergic receptor.

Q05062	CDC42_CAEEL	Cell division control protein 42 homolog	11412997	CDC-42 controls early cell polarity and spindle orientation in C. elegans.

Q9UT48	EIF3H_SCHPO	Eukaryotic translation initiation factor 3 subunit H	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P01606	KV114_HUMAN	Ig kappa chain V-I region OU	5447531	Macroglobulin structure: variable sequence of light and heavy chains.

Q13304	GPR17_HUMAN	Uracil nucleotide/cysteinyl leukotriene receptor	16990797	The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor.

P37840	SYUA_HUMAN	Alpha-synuclein	8248242	Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease.

Q02910	CPN_DROME	Calphotin	8434015	A Drosophila photoreceptor cell-specific protein, calphotin, binds calcium and contains a leucine zipper.

O42980	NEP1_SCHPO	NEDD8-specific protease 1	15769255	Nep1, a Schizosaccharomyces pombe deneddylating enzyme.

Q9LKJ1	HIBC1_ARATH	3-hydroxyisobutyryl-CoA hydrolase 1	11404361	chy1, an Arabidopsis mutant with impaired beta-oxidation, is defective in a peroxisomal beta-hydroxyisobutyryl-CoA hydrolase.

O80517	BCB2_ARATH	Uclacyanin-2	12805588	Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis.

O60118	RM23_SCHPO	60S ribosomal protein L23, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q7G9P4	ALDO3_ARATH	Abscisic-aldehyde oxidase	11050171	The Arabidopsis aldehyde oxidase 3 (AAO3) gene product catalyzes the final step in abscisic acid biosynthesis in leaves.

P53008	CWH41_YEAST	Mannosyl-oligosaccharide glucosidase	8576053	CWH41 encodes a novel endoplasmic reticulum membrane N-glycoprotein involved in beta 1,6-glucan assembly.

O00291	HIP1_HUMAN	Huntingtin-interacting protein 1	11788820	Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi.

Q9P896	TCSA_EMENI	Two-component system protein A	10905426	A novel 'two-component' protein containing histidine kinase and response regulator domains required for sporulation in Aspergillus nidulans.

O94271	YORN_SCHPO	Uncharacterized RING finger protein P8B7.23	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q6PB66	LPPRC_MOUSE	Leucine-rich PPR motif-containing protein, mitochondrial	17050673	Defects in energy homeostasis in Leigh syndrome French Canadian variant through PGC-1alpha/LRP130 complex.

Q3URR7	ZSC10_MOUSE	Zinc finger and SCAN domain-containing protein 10	16971461	Zfp206 regulates ES cell gene expression and differentiation.

O00273	DFFA_HUMAN	DNA fragmentation factor subunit alpha	9108473	DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis.

Q9Y5Z4	HEBP2_HUMAN	Heme-binding protein 2	17098234	Induction of necrotic cell death and mitochondrial permeabilization by heme binding protein 2/SOUL.

P48994	TRPL_DROME	Transient-receptor-potential-like protein	11707492	Phototransduction in Drosophila melanogaster.

Q10325	MST2_SCHPO	Histone acetyltransferase mst2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O43749	OR1F1_HUMAN	Olfactory receptor 1F1	9500546	Distribution of olfactory receptor genes in the human genome.

O00468	AGRIN_HUMAN	Agrin	9151673	Agrin binds to the nerve-muscle basal lamina via laminin.

Q9GZQ4	NMUR2_HUMAN	Neuromedin-U receptor 2	10899166	Identification and characterization of two neuromedin U receptors differentially expressed in peripheral tissues and the central nervous system.

B7EZJ7	HS23M_ORYSJ	23.6 kDa heat shock protein, mitochondrial	19703271	Rice sHsp genes: genomic organization and expression profiling under stress and development.

O35820	RCL_RAT	Deoxyribonucleoside 5'-monophosphate N-glycosidase	9271375	Identification of putative c-Myc-responsive genes: characterization of rcl, a novel growth-related gene.

P20781	GLRB_RAT	Glycine receptor subunit beta	15574743	Single-channel behavior of heteromeric alpha1beta glycine receptors: an attempt to detect a conformational change before the channel opens.

P80428	ARP4_YEAST	Actin-related protein 4	14645854	ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex.

P21961	CBPA3_RAT	Mast cell carboxypeptidase A	8996238	Secretory granule proteases in rat mast cells. Cloning of 10 different serine proteases and a carboxypeptidase A from various rat mast cell populations.

P53673	CRBA4_HUMAN	Beta-crystallin A4	8999933	Sequence analysis of betaA3, betaB3, and betaA4 crystallins completes the identification of the major proteins in young human lens.

Q01560	NOP3_YEAST	Nucleolar protein 3	7962083	Characterization of nuclear polyadenylated RNA-binding proteins in Saccharomyces cerevisiae.

Q9BZR8	B2L14_HUMAN	Apoptosis facilitator Bcl-2-like protein 14	11054413	Bcl-G, a novel pro-apoptotic member of the Bcl-2 family.

O16850	FOXO_CAEEL	Forkhead box protein O	19103192	Combined informatic and expression screen identifies the novel DAF-16 target HLH-13.

P06103	EIF3B_YEAST	Eukaryotic translation initiation factor 3 subunit B	9671501	Identification of a translation initiation factor 3 (eIF3) core complex, conserved in yeast and mammals, that interacts with eIF5.

Q9UUJ8	YLOA_SCHPO	UPF0658 Golgi apparatus membrane protein C1952.10c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O13927	THT2_SCHPO	Twin horsetail protein 2	16303567	A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

Q00947	STP1_YEAST	Transcription factor STP1	11212916	Transcriptional regulation of the Saccharomyces cerevisiae amino acid permease gene BAP2.

Q3UUY6	PROM2_MOUSE	Prominin-2	12514187	Characterization of prominin-2, a new member of the prominin family of pentaspan membrane glycoproteins.

Q03042	KGP1_DROME	cGMP-dependent protein kinase, isozyme 1	8798533	Biochemical properties and cellular localization of the Drosophila DG1 cGMP-dependent protein kinase.

Q12248	DAD1_YEAST	DASH complex subunit DAD1	15664196	Formation of a dynamic kinetochore-microtubule interface through assembly of the Dam1 ring complex.

O95150	TNF15_HUMAN	Tumor necrosis factor ligand superfamily member 15	9872942	VEGI, a novel cytokine of the tumor necrosis factor family, is an angiogenesis inhibitor that suppresses the growth of colon carcinomas in vivo.

Q8WWY3	PRP31_HUMAN	U4/U6 small nuclear ribonucleoprotein Prp31	15960975	Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

O95972	BMP15_HUMAN	Bone morphogenetic protein 15	9849956	The bone morphogenetic protein 15 gene is X-linked and expressed in oocytes.

Q8ITC7	CAPAR_DROME	Neuropeptides capa receptor	12177421	Identification of G protein-coupled receptors for Drosophila PRXamide peptides, CCAP, corazonin, and AKH supports a theory of ligand- receptor coevolution.

O14625	CXL11_HUMAN	C-X-C motif chemokine 11	10233762	Human IP-9: a keratinocyte derived high affinity CXC-chemokine ligand for the IP-10/Mig receptor (CXCR3).

Q06991	YL414_YEAST	Cell membrane protein YLR414C	14562095	Global analysis of protein localization in budding yeast.

Q9P0J0	NDUAD_HUMAN	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	10924506	Identification of GRIM-19, a novel cell death-regulatory gene induced by the interferon-beta and retinoic acid combination, using a genetic approach.

Q5XJ85	MYD88_DANRE	Myeloid differentiation primary response protein MyD88	16552074	MyD88 innate immune function in a zebrafish embryo infection model.

Q8K4B2	IRAK3_MOUSE	Interleukin-1 receptor-associated kinase 3	12054681	Identification and characterization of murine IRAK-M.

O43390	HNRPR_HUMAN	Heterogeneous nuclear ribonucleoprotein R	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

Q04721	NOTC2_HUMAN	Neurogenic locus notch homolog protein 2	10079256	Human ligands of the Notch receptor.

P30186	PSA7A_ARATH	Proteasome subunit alpha type-7-A	11387208	SKP1-SnRK protein kinase interactions mediate proteasomal binding of a plant SCF ubiquitin ligase.

O76329	ACTNB_DICDI	Interaptin	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

P33418	XPOT_YEAST	Exportin-T	18045534	Impaired tRNA nuclear export links DNA damage and cell-cycle checkpoint.

Q64093	S6A20_RAT	Sodium- and chloride-dependent transporter XTRP3	15632147	Identification of mammalian proline transporter SIT1 (SLC6A20) with characteristics of classical system imino.

Q9UTA3	YL8H_SCHPO	Probable intramembrane protease C25B8.17	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9UUZ4	AGALC_ASPNG	Alpha-galactosidase C	11358516	Cloning and characterization of Aspergillus niger genes encoding an alpha-galactosidase and a beta-mannosidase involved in galactomannan degradation.

P38316	ATG12_YEAST	Ubiquitin-like protein ATG12	10233150	Apg7p/Cvt2p: a novel protein-activating enzyme essential for autophagy.

Q9Y5S1	TRPV2_HUMAN	Transient receptor potential cation channel subfamily V member 2	10201375	A capsaicin-receptor homologue with a high threshold for noxious heat.

P42891	ECE1_BOVIN	Endothelin-converting enzyme 1	7805846	Molecular characterization of human and bovine endothelin converting enzyme (ECE-1).

P09217	KPCZ_RAT	Protein kinase C zeta type	12431995	ZIP3, a new splice variant of the PKC-zeta-interacting protein family, binds to GABAC receptors, PKC-zeta, and Kv beta 2.

P34756	FAB1_YEAST	1-phosphatidylinositol-3-phosphate 5-kinase FAB1	19037259	VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P(2) in yeast and mouse.

Q96RU2	UBP28_HUMAN	Ubiquitin carboxyl-terminal hydrolase 28	16901786	A role for the deubiquitinating enzyme USP28 in control of the DNA- damage response.

Q9XGN1	TTG1_ARATH	Protein TRANSPARENT TESTA GLABRA 1	10402433	The TRANSPARENT TESTA GLABRA1 locus, which regulates trichome differentiation and anthocyanin biosynthesis in Arabidopsis, encodes a WD40 repeat protein.

P46997	JJJ2_YEAST	J protein JJJ2	14562095	Global analysis of protein localization in budding yeast.

Q17307	TRA2_CAEBR	Sex-determining transformer protein 2	12477393	Rapid coevolution of the nematode sex-determining genes fem-3 and tra-2.

Q9UPY6	WASF3_HUMAN	Wiskott-Aldrich syndrome protein family member 3	10381382	Identification of two human WAVE/SCAR homologues as general actin regulatory molecules which associate with the Arp2/3 complex.

P84794	AFPJ_SOLTU	Antifungal protein J	16076139	Kunitz-type serine protease inhibitor from potato (Solanum tuberosum L. cv. Jopung).

Q9W278	MED16_DROME	Mediator of RNA polymerase II transcription subunit 16	15297616	MED16 and MED23 of Mediator are coactivators of lipopolysaccharide- and heat-shock-induced transcriptional activators.

Q9GZU7	CTDS1_HUMAN	Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1	12721286	A novel RNA polymerase II C-terminal domain phosphatase that preferentially dephosphorylates serine 5.

Q06090	RM51_YEAST	54S ribosomal protein L51, mitochondrial	12392552	Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components.

P42581	HMX3_MOUSE	Homeobox protein HMX3	9435283	Inner ear and maternal reproductive defects in mice lacking the Hmx3 homeobox gene.

Q9H207	O10A5_HUMAN	Olfactory receptor 10A5	9787077	Organization and evolution of olfactory receptor genes on human chromosome 11.

P22509	FBRL_RAT	rRNA 2'-O-methyltransferase fibrillarin	2414294	Purification and partial characterization of a nucleolar scleroderma antigen (Mr = 34,000; pI, 8.5) rich in NG,NG-dimethylarginine.

Q05946	UTP13_YEAST	U3 small nucleolar RNA-associated protein 13	12068309	A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis.

P56199	ITA1_HUMAN	Integrin alpha-1	8428973	Expression of native and truncated forms of the human integrin alpha 1 subunit.

Q9NQL2	RRAGD_HUMAN	Ras-related GTP-binding protein D	11073942	Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B.

Q9QXE0	HACL1_MOUSE	2-hydroxyacyl-CoA lyase 1	11171065	Prenatal and postnatal development of peroxisomal lipid-metabolizing pathways in the mouse.

Q14494	NF2L1_HUMAN	Nuclear factor erythroid 2-related factor 1	8248256	Cloning of Nrf1, an NF-E2-related transcription factor, by genetic selection in yeast.

Q7YSW8	PP2BA_DICDI	Calcineurin subunit A	8681950	Primary structure, expression and developmental regulation of a Dictyostelium calcineurin A homologue.

P05791	ILVD_ECOLI	Dihydroxy-acid dehydratase	8325851	The role and properties of the iron-sulfur cluster in Escherichia coli dihydroxy-acid dehydratase.

P32447	ASF1_YEAST	Histone chaperone ASF1	11731479	The yeast SAS (something about silencing) protein complex contains a MYST-type putative acetyltransferase and functions with chromatin assembly factor ASF1.

P23381	SYWC_HUMAN	Tryptophanyl-tRNA synthetase, cytoplasmic	15628863	Oxidative stress-responsive intracellular regulation specific for the angiostatic form of human tryptophanyl-tRNA synthetase.

Q99MG9	KCIP4_RAT	Kv channel-interacting protein 4	11805342	Elimination of fast inactivation in Kv4 A-type potassium channels by an auxiliary subunit domain.

P57081	WDR4_HUMAN	tRNA (guanine-N(7)-)-methyltransferase subunit WDR4	15861136	The tRNA methylase METTL1 is phosphorylated and inactivated by PKB and RSK in vitro and in cells.

Q14164	IKKE_HUMAN	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	18636086	The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response.

P48180	ACH1_CAEEL	Acetylcholine receptor subunit alpha-type acr-16	15944127	The Ror receptor tyrosine kinase CAM-1 is required for ACR-16- mediated synaptic transmission at the C. elegans neuromuscular junction.

P08965	MEI2_SCHPO	Meiosis protein mei2	11818066	14-3-3 protein interferes with the binding of RNA to the phosphorylated form of fission yeast meiotic regulator Mei2p.

P40077	DSE1_YEAST	Protein DSE1	11309124	Overlapping and distinct roles of the duplicated yeast transcription factors Ace2p and Swi5p.

O74915	YJ74_SCHPO	Uncharacterized transcriptional regulatory protein C757.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q3UNX5	ACSM3_MOUSE	Acyl-coenzyme A synthetase ACSM3, mitochondrial	11470804	Molecular identification and characterization of two medium-chain acyl-CoA synthetases, MACS1 and the Sa gene product.

B3PGJ1	AGAL_CELJU	Alpha-galactosidase A	11064195	alpha-Galactosidase A from Pseudomonas fluorescens subsp. cellulosa: cloning, high level expression and its role in galactomannan hydrolysis.

Q95VE9	PBP1_EPIPO	Pheromone-binding protein 1	12530222	Pheromone binding proteins of Epiphyas postvittana (Lepidoptera: Tortricidae) are encoded at a single locus.

Q9NA13	IPLA_DICDI	Inositol 1,4,5-trisphosphate receptor-like protein A	10970875	Ca(2+) signalling is not required for chemotaxis in Dictyostelium.

P46935	NEDD4_MOUSE	E3 ubiquitin-protein ligase NEDD4	11042109	Identification of multiple proteins expressed in murine embryos as binding partners for the WW domains of the ubiquitin-protein ligase Nedd4.

P10124	SRGN_HUMAN	Serglycin	11154222	Synthesis, secretion, and subcellular localization of serglycin proteoglycan in human endothelial cells.

Q9HE05	UFD2_SCHPO	Ubiquitin conjugation factor E4	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

Q9C7S5	PSYR1_ARATH	Tyrosine-sulfated glycopeptide receptor 1	17989228	Tyrosine-sulfated glycopeptide involved in cellular proliferation and expansion in Arabidopsis.

O88552	CLD2_MOUSE	Claudin-2	9647647	Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin.

P60866	RS20_HUMAN	40S ribosomal protein S20	8479924	Human ribosomal protein S20 cDNA sequence.

O08961	ZN423_RAT	Zinc finger protein 423	9774661	Identification of DNA recognition sequences and protein interaction domains of the multiple-Zn-finger protein Roaz.

Q04746	KAR5_YEAST	Nuclear fusion protein KAR5	10069807	Genetic interactions between KAR7/SEC71, KAR8/JEM1, KAR5, and KAR2 during nuclear fusion in Saccharomyces cerevisiae.

Q24312	EWG_DROME	DNA-binding protein Ewg	10330140	Differential and inefficient splicing of a broadly expressed Drosophila erect wing transcript results in tissue-specific enrichment of the vital EWG protein isoform.

Q08601	MCA1_YEAST	Metacaspase-1	11983181	A caspase-related protease regulates apoptosis in yeast.

O94437	YFI3_SCHPO	Abhydrolase domain-containing protein C22H12.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9C550	LEU12_ARATH	2-isopropylmalate synthase 2, chloroplastic	15155874	Glucosinolate and amino acid biosynthesis in Arabidopsis.

P30048	PRDX3_HUMAN	Thioredoxin-dependent peroxide reductase, mitochondrial	7733872	Mammalian antioxidant protein complements alkylhydroperoxide reductase (ahpC) mutation in Escherichia coli.

O95271	TNKS1_HUMAN	Tankyrase-1	12768206	POT1 as a terminal transducer of TRF1 telomere length control.

Q8I615	ORC1_PLAF7	Origin recognition complex subunit 1	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

Q9LZM7	PR1A1_ARATH	PRA1 family protein A1	18583532	The PRA1 gene family in Arabidopsis.

Q16853	AOC3_HUMAN	Membrane primary amine oxidase	9653080	Cloning of vascular adhesion protein 1 reveals a novel multifunctional adhesion molecule.

P32561	RPD3_YEAST	Histone deacetylase RPD3	9710596	Targeted recruitment of the Sin3-Rpd3 histone deacetylase complex generates a highly localized domain of repressed chromatin in vivo.

Q9VM92	TTL3B_DROME	Tubulin glycylase 3B	19524510	Evolutionary divergence of enzymatic mechanisms for posttranslational polyglycylation.

Q13950	RUNX2_HUMAN	Runt-related transcription factor 2	12145306	Regulation of osteocalcin gene expression by a novel Ku antigen transcription factor complex.

Q99JB3	FUT9_RAT	Alpha-(1,3)-fucosyltransferase	11675393	Pax6 controls the expression of Lewis x epitope in the embryonic forebrain by regulating alpha 1,3-fucosyltransferase IX expression.

Q9ER30	KBTBA_RAT	Kelch repeat and BTB domain-containing protein 10	10713668	Krp1, a novel kelch related protein that is involved in pseudopod elongation in transformed cells.

Q9NQC7	CYLD_HUMAN	Ubiquitin carboxyl-terminal hydrolase CYLD	20227366	Loss of the tumor suppressor CYLD enhances Wnt/beta-catenin signaling through K63-linked ubiquitination of Dvl.

Q9VYX7	PGPSA_DROME	Peptidoglycan-recognition protein SA	14684822	Dual activation of the Drosophila toll pathway by two pattern recognition receptors.

O14306	YE8A_SCHPO	Probable inositol polyphosphate 5-phosphatase C9G1.10c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P38873	KOG1_YEAST	Target of rapamycin complex 1 subunit KOG1	12408816	Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control.

O88751	CABP1_RAT	Calcium-binding protein 1	9694893	Caldendrin, a novel neuronal calcium-binding protein confined to the somato-dendritic compartment.

P31785	IL2RG_HUMAN	Cytokine receptor common subunit gamma	8514792	Characterization of the human interleukin-2 receptor gamma chain gene.

Q9Y3P8	SIT1_HUMAN	Signaling threshold-regulating transmembrane adapter 1	10209036	SHP2-interacting transmembrane adaptor protein (SIT), a novel disulfide-linked dimer regulating human T-cell activation.

P11911	CD79A_MOUSE	B-cell antigen receptor complex-associated protein alpha chain	11238609	Translocation of the B cell antigen receptor into lipid rafts reveals a novel step in signaling.

Q13098	CSN1_HUMAN	COP9 signalosome complex subunit 1	8943324	Two human cDNAs, including a homolog of Arabidopsis FUS6 (COP11), suppress G-protein- and mitogen-activated protein kinase-mediated signal transduction in yeast and mammalian cells.

P02763	A1AG1_HUMAN	Alpha-1-acid glycoprotein 1	2822385	Structure and expression of the genes coding for human alpha 1-acid glycoprotein.

Q9P7T0	SIB2_SCHPO	L-ornithine 5-monooxygenase	15689108	Ferrichrome in Schizosaccharomyces pombe -- an iron transport and iron storage compound.

P54360	FOJO_DROME	Protein four-jointed	11566858	Four-jointed interacts with dachs, abelson and enabled and feeds back onto the Notch pathway to affect growth and segmentation in the Drosophila leg.

Q6K7E9	HS186_ORYSJ	18.6 kDa class III heat shock protein	19703271	Rice sHsp genes: genomic organization and expression profiling under stress and development.

P31652	SC6A4_RAT	Sodium-dependent serotonin transporter	10716733	Oligomerization of serotonin transporter and its functional consequences.

Q9NTG7	SIRT3_HUMAN	NAD-dependent deacetylase sirtuin-3, mitochondrial	10381378	Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity.

Q29980	MICB_HUMAN	MHC class I polypeptide-related sequence B	9497295	Recognition of stress-induced MHC molecules by intestinal epithelial gammadelta T cells.

Q06525	URN1_YEAST	Pre-mRNA-splicing factor URN1	14562095	Global analysis of protein localization in budding yeast.

P35602	AP1M_CAEEL	AP-1 complex subunit mu-1-I	8288128	unc-101, a gene required for many aspects of Caenorhabditis elegans development and behavior, encodes a clathrin-associated protein.

Q13496	MTM1_HUMAN	Myotubularin	8640223	A gene mutated in X-linked myotubular myopathy defines a new putative tyrosine phosphatase family conserved in yeast.

P38228	TCM62_YEAST	Mitochondrial chaperone TCM62	9822678	The Saccharomyces cerevisiae TCM62 gene encodes a chaperone necessary for the assembly of the mitochondrial succinate dehydrogenase (complex II).

P08365	CHPS_ECOLI	PemI-like protein 2	8226627	chpA and chpB, Escherichia coli chromosomal homologs of the pem locus responsible for stable maintenance of plasmid R100.

O95619	YETS4_HUMAN	YEATS domain-containing protein 4	11903063	Interaction of the transforming acidic coiled-coil 1 (TACC1) protein with ch-TOG and GAS41/NuBI1 suggests multiple TACC1-containing protein complexes in human cells.

O94916	NFAT5_HUMAN	Nuclear factor of activated T-cells 5	10051678	Tonicity-responsive enhancer binding protein, a rel-like protein that stimulates transcription in response to hypertonicity.

P28845	DHI1_HUMAN	Corticosteroid 11-beta-dehydrogenase isozyme 1	1885595	The human gene for 11 beta-hydroxysteroid dehydrogenase. Structure, tissue distribution, and chromosomal localization.

Q8IM77	YPFJ1_PLAF7	Uncharacterized J domain-containing protein PF14_0013	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

P32781	AGA2_YEAST	A-agglutinin-binding subunit	7957044	Mating type-specific cell-cell recognition of Saccharomyces cerevisiae: cell wall attachment and active sites of a- and alpha- agglutinin.

Q02804	ARL3_YEAST	ADP-ribosylation factor-like protein 3	9920936	Characterization of a novel ADP-ribosylation factor-like protein (yARL3) in Saccharomyces cerevisiae.

O95741	CPNE6_HUMAN	Copine-6	9645480	N-copine: a novel two C2-domain-containing protein with neuronal activity-regulated expression.

P18296	CUT1_SCHPO	Separin	12390246	Cut1/separase C-terminus affects spindle pole body positioning in interphase of fission yeast: pointed nuclear formation.

P53083	MDM34_YEAST	Mitochondrial distribution and morphology protein 34	11907266	Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae.

Q96B36	AKTS1_HUMAN	Proline-rich AKT1 substrate 1	12524439	Identification of a proline-rich Akt substrate as a 14-3-3 binding partner.

O13660	YBC9_SCHPO	Uncharacterized mitochondrial carrier C27B12.09c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9NY84	VNN3_HUMAN	Vascular non-inflammatory molecule 3	11491533	Vanin genes are clustered (human 6q22-24 and mouse 10A2B1) and encode isoforms of pantetheinase ectoenzymes.

O60260	PRKN2_HUMAN	E3 ubiquitin-protein ligase parkin	9560156	Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism.

Q811T9	DISC1_MOUSE	Disrupted in schizophrenia 1 homolog	19778506	DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212.

P0C869	PA24B_HUMAN	Cytosolic phospholipase A2 beta	10358058	Molecular characterization of cytosolic phospholipase A2-beta.

P32799	COX13_YEAST	Cytochrome c oxidase subunit 6A, mitochondrial	1331058	Purification of yeast cytochrome c oxidase with a subunit composition resembling the mammalian enzyme.

Q5XPK0	SCARL_ARATH	Scar-like domain-containing protein WAVE 5	17267444	The role of Arabidopsis SCAR genes in ARP2-ARP3-dependent cell morphogenesis.

P17784	ALF_ORYSJ	Fructose-bisphosphate aldolase cytoplasmic isozyme	2374721	Nucleotide sequence of the rice cytoplasmic aldolase cDNA.

Q9DCY0	KEG1_MOUSE	Glycine N-acyltransferase-like protein Keg1	14651853	Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.

Q9UHC6	CNTP2_HUMAN	Contactin-associated protein-like 2	10624965	Caspr2, a new member of the neurexin superfamily, is localized at the juxtaparanodes of myelinated axons and associates with K+ channels.

Q06628	ATG13_YEAST	Autophagy-related protein 13	9224892	Analyses of APG13 gene involved in autophagy in yeast, Saccharomyces cerevisiae.

Q9UUA5	MTXL_SCHPO	Metaxin-like protein C409.19c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9BY10	TSCOT_HUMAN	Thymic stromal cotransporter homolog	10978518	Characterization of the mouse gene, human promoter and human cDNA of TSCOT reveals strong interspecies homology.

Q9BYV8	CEP41_HUMAN	Centrosomal protein of 41 kDa	14654843	Proteomic characterization of the human centrosome by protein correlation profiling.

Q9FK25	OMT1_ARATH	Quercetin 3-O-methyltransferase 1	9349713	An Arabidopsis gene encoding a putative 14-3-3-interacting protein, caffeic acid/5-hydroxyferulic acid O-methyltransferase.

P97358	TAF1B_MOUSE	TATA box-binding protein-associated factor RNA polymerase I subunit B	9050847	Cloning of murine RNA polymerase I-specific TAF factors: conserved interactions between the subunits of the species-specific transcription initiation factor TIF-IB/SL1.

P84870	LEC1_HYPCE	Lectin-1	16046632	HCA and HML isolated from the red marine algae Hypnea cervicornis and Hypnea musciformis define a novel lectin family.

O81275	CSK2D_ARATH	Casein kinase II subunit beta-3	9724822	Protein kinase CK2 interacts with and phosphorylates the Arabidopsis circadian clock-associated 1 protein.

P15619	SRYC_DROME	Serendipity locus protein H-1	1592256	The Drosophila pourquoi-pas?/wings-down zinc finger protein: oocyte nucleus localization and embryonic requirement.

Q95SP2	HRD1_DROME	E3 ubiquitin-protein ligase HRD1	17170702	Cytoplasmic destruction of p53 by the endoplasmic reticulum-resident ubiquitin ligase 'Synoviolin'.

O75953	DNJB5_HUMAN	DnaJ homolog subfamily B member 5	10570961	Hsc40, a new member of the hsp40 family, exhibits similar expression profile to that of hsc70 in mammalian cells.

P25336	MSH3_YEAST	DNA mismatch repair protein MSH3	9256462	Role of Saccharomyces cerevisiae Msh2 and Msh3 repair proteins in double-strand break-induced recombination.

Q7K237	C1GLT_DROME	Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1	18985719	Requirement for a core 1 galactosyltransferase in the Drosophila nervous system.

Q9UNX4	WDR3_HUMAN	WD repeat-containing protein 3	10395803	Cloning and expression analysis of a novel WD repeat gene, WDR3, mapping to 1p12-p13.

Q15652	JHD2C_HUMAN	Probable JmjC domain-containing histone demethylation protein 2C	7776974	Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor.

O88575	S620B_MOUSE	Sodium- and chloride-dependent transporter XTRP3B	9932288	Cloning, gene structure, and genomic localization of an orphan transporter from mouse kidney with six alternatively-spliced isoforms.

Q16568	CART_HUMAN	Cocaine- and amphetamine-regulated transcript protein	8647455	Characterization of the human cDNA and genomic DNA encoding CART: a cocaine- and amphetamine-regulated transcript.

P52481	CAP2_RAT	Adenylyl cyclase-associated protein 2	8522189	Differential expression of CAP and CAP2 in adult rat tissues.

P32447	ASF1_YEAST	Histone chaperone ASF1	16678113	Asf1 mediates histone eviction and deposition during elongation by RNA polymerase II.

P36603	RIR2_SCHPO	Ribonucleoside-diphosphate reductase small chain	8479429	The cell cycle genes cdc22+ and suc22+ of the fission yeast Schizosaccharomyces pombe encode the large and small subunits of ribonucleotide reductase.

P05626	ATPF_YEAST	ATP synthase subunit 4, mitochondrial	2553130	The yeast ATP synthase subunit 4: structure and function.

Q9GZM8	NDEL1_HUMAN	Nuclear distribution protein nudE-like 1	17035248	DISC1-NDEL1/NUDEL protein interaction, an essential component for neurite outgrowth, is modulated by genetic variations of DISC1.

Q60749	KHDR1_MOUSE	KH domain-containing, RNA-binding, signal transduction-associated protein 1	7799925	Association of p62, a multifunctional SH2- and SH3-domain-binding protein, with src family tyrosine kinases, Grb2, and phospholipase C gamma-1.

Q96RU3	FNBP1_HUMAN	Formin-binding protein 1	14596906	The formin-binding protein 17, FBP17, binds via a TNKS binding motif to tankyrase, a protein involved in telomere maintenance.

Q6NXT6	TAPT1_HUMAN	Transmembrane anterior posterior transformation protein 1 homolog	10640539	Cloning and epitope mapping of a functional partial fusion receptor for human cytomegalovirus gH.

O70150	KCC1B_RAT	Calcium/calmodulin-dependent protein kinase type 1B	9405489	Isoform-specific activation and structure diversity of calmodulin kinase I.

A1ZBT5	MED8_DROME	Mediator of RNA polymerase II transcription subunit 8	16751183	Coactivator cross-talk specifies transcriptional output.

P81918	OR43B_DROME	Odorant receptor 43b	10069338	A novel family of divergent seven-transmembrane proteins: candidate odorant receptors in Drosophila.

P23229	ITA6_HUMAN	Integrin alpha-6	2649503	Association of the VLA alpha 6 subunit with a novel protein. A possible alternative to the common VLA beta 1 subunit on certain cell lines.

Q9Y4I1	MYO5A_HUMAN	Myosin-Va	10448864	Myosin-V is a processive actin-based motor.

Q01658	NC2B_HUMAN	Protein Dr1	1339312	Dr1, a TATA-binding protein-associated phosphoprotein and inhibitor of class II gene transcription.

Q20696	SMSR1_CAEEL	Sphingomyelin synthase-related 1	14685263	Identification of a family of animal sphingomyelin synthases.

P38293	UMP1_YEAST	Proteasome maturation factor UMP1	9491890	Ump1p is required for proper maturation of the 20S proteasome and becomes its substrate upon completion of the assembly.

P11911	CD79A_MOUSE	B-cell antigen receptor complex-associated protein alpha chain	16860757	The B cell receptor promotes B cell activation and proliferation through a non-ITAM tyrosine in the Igalpha cytoplasmic domain.

Q10133	RHO2_SCHPO	GTP-binding protein rho2	9405296	Genes that cause aberrant cell morphology by overexpression in fission yeast: a role of a small GTP-binding protein Rho2 in cell morphogenesis.

P47712	PA24A_HUMAN	Cytosolic phospholipase A2	9430701	Crystal structure of a calcium-phospholipid binding domain from cytosolic phospholipase A2.

O43030	FES1_SCHPO	Hsp70 nucleotide exchange factor fes1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P55861	MCM2_XENLA	DNA replication licensing factor mcm2	16369567	The ATPase activity of MCM2-7 is dispensable for pre-RC assembly but is required for DNA unwinding.

P49597	P2C56_ARATH	Protein phosphatase 2C 56	16365038	The regulatory domain of SRK2E/OST1/SnRK2.6 interacts with ABI1 and integrates abscisic acid (ABA) and osmotic stress signals controlling stomatal closure in Arabidopsis.

P0ABF8	PGSA_ECOLI	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	3003065	Structure and expression of the gene locus encoding the phosphatidylglycerophosphate synthase of Escherichia coli.

Q9Y7R4	SET1_SCHPO	Histone-lysine N-methyltransferase, H3 lysine-4 specific	12589755	The fission yeast spSet1p is a histone H3-K4 methyltransferase that functions in telomere maintenance and DNA repair in an ATM kinase Rad3-dependent pathway.

Q9C5X8	MOCOS_ARATH	Molybdenum cofactor sulfurase	11553608	ABA3 is a molybdenum cofactor sulfurase required for activation of aldehyde oxidase and xanthine dehydrogenase in Arabidopsis thaliana.

P81915	OR33B_DROME	Odorant receptor 33b	10089887	A spatial map of olfactory receptor expression in the Drosophila antenna.

P53534	PYGB_RAT	Glycogen phosphorylase, brain form	7916624	Comparative analysis of species-independent, isozyme-specific amino- acid substitutions in mammalian muscle, brain and liver glycogen phosphorylases.

P32448	ASF2_YEAST	Anti-silencing protein 2	9290207	Two new S-phase-specific genes from Saccharomyces cerevisiae.

Q61644	PACN1_MOUSE	Protein kinase C and casein kinase substrate in neurons protein 1	9746365	PACSIN, a brain protein that is upregulated upon differentiation into neuronal cells.

Q96EE3	SEH1_HUMAN	Nucleoporin SEH1	17363900	The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions.

P40791	MEF2_DROME	Myocyte-specific enhancer factor 2	7839146	Requirement of MADS domain transcription factor D-MEF2 for muscle formation in Drosophila.

Q92843	B2CL2_HUMAN	Bcl-2-like protein 2	8761287	Bcl-w, a novel member of the Bcl-2 family, promotes cell survival.

Q10075	PCS_SCHPO	Glutathione gamma-glutamylcysteinyltransferase	10368185	Phytochelatin synthase genes from Arabidopsis and the yeast Schizosaccharomyces pombe.

P28286	5HT2B_DROME	5-hydroxytryptamine receptor 2B	1310937	A family of Drosophila serotonin receptors with distinct intracellular signalling properties and expression patterns.

Q9NR56	MBNL1_HUMAN	Muscleblind-like protein 1	18335541	MBNL1 associates with YB-1 in cytoplasmic stress granules.

Q0P436	TM14C_DANRE	Transmembrane protein 14C	19656490	Discovery of genes essential for heme biosynthesis through large- scale gene expression analysis.

O95072	REC8_HUMAN	Meiotic recombination protein REC8 homolog	10207075	Rec8p, a meiotic recombination and sister chromatid cohesion phosphoprotein of the Rad21p family conserved from fission yeast to humans.

Q86UX7	URP2_HUMAN	Fermitin family homolog 3	19234463	Leukocyte adhesion deficiency-III is caused by mutations in KINDLIN3 affecting integrin activation.

Q54TH8	TCPG_DICDI	T-complex protein 1 subunit gamma	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

P51864	TDGF2_HUMAN	Putative teratocarcinoma-derived growth factor 2	1882841	Isolation and characterization of the CRIPTO autosomal gene and its X-linked related sequence.

Q9ULL8	SHRM4_HUMAN	Protein Shroom4	16249884	Disruptions of the novel KIAA1202 gene are associated with X-linked mental retardation.

P30460	1B08_HUMAN	HLA class I histocompatibility antigen, B-8 alpha chain	8976183	Antagonist HIV-1 Gag peptides induce structural changes in HLA B8.

Q9NPC6	MYOZ2_HUMAN	Myozenin-2	16076904	The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins.

O95835	LATS1_HUMAN	Serine/threonine-protein kinase LATS1	10518011	A human homolog of Drosophila warts tumor suppressor, h-warts, localized to mitotic apparatus and specifically phosphorylated during mitosis.

Q60954	MEIS1_MOUSE	Homeobox protein Meis1	15882575	The homeodomain protein Meis1 is essential for definitive hematopoiesis and vascular patterning in the mouse embryo.

P36027	MID2_YEAST	Cell wall integrity sensor MID2	10348843	Saccharomyces cerevisiae mid2p is a potential cell wall stress sensor and upstream activator of the PKC1-MPK1 cell integrity pathway.

Q9UPR3	SMG5_HUMAN	Protein SMG5	14636577	Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7.

Q63089	S22A1_RAT	Solute carrier family 22 member 1	9776363	Catecholamine transport by the organic cation transporter type 1 (OCT1).

Q53080	PSA1_RHOER	Proteasome subunit alpha 1	7583123	The first characterization of a eubacterial proteasome: the 20S complex of Rhodococcus.

Q38861	XPB1_ARATH	DNA repair helicase XPB1	15656976	Functional XPB/RAD25 redundancy in Arabidopsis genome: characterization of AtXPB2 and expression analysis.

P23503	NAR1_YEAST	Cytosolic Fe-S cluster assembly factor NAR1	15103330	The hydrogenase-like Nar1p is essential for maturation of cytosolic and nuclear iron-sulphur proteins.

Q9Y653	GPR56_HUMAN	G-protein coupled receptor 56	10049584	GPR56, a novel secretin-like human G-protein-coupled receptor gene.

Q9QWY8	ASAP1_MOUSE	Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1	9819391	ASAP1, a phospholipid-dependent arf GTPase-activating protein that associates with and is phosphorylated by Src.

Q12080	NOP53_YEAST	Ribosome biogenesis protein NOP53	16128814	Nop53p, an essential nucleolar protein that interacts with Nop17p and Nip7p, is required for pre-rRNA processing in Saccharomyces cerevisiae.

Q9S7Q7	FLC_ARATH	MADS-box protein FLOWERING LOCUS C	10716723	The molecular basis of vernalization: the central role of FLOWERING LOCUS C (FLC).

P50120	RET2_HUMAN	Retinol-binding protein 2	7657783	Variation in the expression of cellular retinoid binding proteins in human endometrium throughout the menstrual cycle.

Q8ND76	CCNY_HUMAN	Cyclin-Y	20059949	Cell cycle control of wnt receptor activation.

P31750	AKT1_MOUSE	RAC-alpha serine/threonine-protein kinase	15753085	A novel protein kinase B (PKB)/AKT-binding protein enhances PKB kinase activity and regulates DNA synthesis.

Q92994	TF3B_HUMAN	Transcription factor IIIB 90 kDa subunit	7624363	Structure and function of a human transcription factor TFIIIB subunit that is evolutionarily conserved and contains both TFIIB- and high- mobility-group protein 2-related domains.

P42527	MHCKA_DICDI	Myosin heavy chain kinase A	7822274	Structural analysis of myosin heavy chain kinase A from Dictyostelium. Evidence for a highly divergent protein kinase domain, an amino-terminal coiled-coil domain, and a domain homologous to the beta-subunit of heterotrimeric G proteins.

Q62717	CAPS1_RAT	Calcium-dependent secretion activator 1	9289490	Novel Ca2+-binding protein (CAPS) related to UNC-31 required for Ca2+-activated exocytosis.

Q9NPC4	A4GAT_HUMAN	Lactosylceramide 4-alpha-galactosyltransferase	10747952	Cloning and expression of the histo-blood group Pk UDP- galactose:Galbeta1-4Glcbeta1-Cer alpha1,4-galactosyltransferase. Molecular genetic basis of the p phenotype.

Q9HD15	SRA1_HUMAN	Steroid receptor RNA activator 1	14517287	Steroid receptor RNA activator stimulates proliferation as well as apoptosis in vivo.

P34233	ASH1_YEAST	Transcriptional regulatory protein ASH1	11171979	Ash1p is a site-specific DNA-binding protein that actively represses transcription.

P23443	KS6B1_HUMAN	Ribosomal protein S6 kinase beta-1	9445476	Phosphorylation and activation of p70s6k by PDK1.

Q06615	NOTO_XENLA	Homeobox protein notochord	11585804	Role of Goosecoid, Xnot and Wnt antagonists in the maintenance of the notochord genetic programme in Xenopus gastrulae.

Q09184	CDB4_SCHPO	Curved DNA-binding protein	7985416	A fission yeast gene encoding a protein that preferentially associates with curved DNA.

Q0JKD0	GLT1_ORYSJ	Glutamate synthase 1 [NADH]	17350935	Assimilation of ammonium ions and reutilization of nitrogen in rice (Oryza sativa L.).

Q04408	YD514_YEAST	Uncharacterized protein YDR514C	14562095	Global analysis of protein localization in budding yeast.

P25156	PSA_THEAC	Proteasome subunit alpha	20019667	Interactions of PAN's C-termini with archaeal 20S proteasome and implications for the eukaryotic proteasome-ATPase interactions.

Q00731	VEGFA_MOUSE	Vascular endothelial growth factor A	1592003	Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation.

Q9FRV0	CHIC_SECCE	Basic endochitinase C	7763659	Purification and some properties of three chitinases from the seeds of rye (Secale cereale).

Q9BQ51	PD1L2_HUMAN	Programmed cell death 1 ligand 2	11283156	B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells.

P52566	GDIR2_HUMAN	Rho GDP-dissociation inhibitor 2	8356058	Ly-GDI, a GDP-dissociation inhibitor of the RhoA GTP-binding protein, is expressed preferentially in lymphocytes.

Q9VLC0	VPS54_DROME	Vacuolar protein sorting-associated protein 54	9550716	Genetic dissection of sperm individualization in Drosophila melanogaster.

Q13368	MPP3_HUMAN	MAGUK p55 subfamily member 3	8824795	Isolation of a gene (DLG3) encoding a second member of the discs- large family on chromosome 17q12-q21.

O43286	B4GT5_HUMAN	Beta-1,4-galactosyltransferase 5	9597550	The expanding beta 4-galactosyltransferase gene family: messages from the databanks.

P06733	ENOA_HUMAN	Alpha-enolase	11134351	A novel 16-kilodalton cellular protein physically interacts with and antagonizes the functional activity of c-myc promoter-binding protein 1.

Q99NA5	IDH3A_RAT	Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial	11237704	Expression of NAD+-dependent isocitrate dehydrogenase in brown adipose tissue.

Q9Y5X9	LIPE_HUMAN	Endothelial lipase	10318835	Cloning of a unique lipase from endothelial cells extends the lipase gene family.

Q9P7W1	YGQ9_SCHPO	Uncharacterized protein C1703.09	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O74521	YCPF_SCHPO	Uncharacterized protein C663.15c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12344	GYP5_YEAST	GTPase-activating protein GYP5	15331637	Gyp5p and Gyl1p are involved in the control of polarized exocytosis in budding yeast.

Q8JIT7	FAST3_XENLA	Forkhead activin signal transducer 3	12374795	Stoichiometry of active smad-transcription factor complexes on DNA.

P16615	AT2A2_HUMAN	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	14749390	TRAM2 protein interacts with endoplasmic reticulum Ca2+ pump Serca2b and is necessary for collagen type I synthesis.

P25627	BUD23_YEAST	Putative methyltransferase BUD23	14562095	Global analysis of protein localization in budding yeast.

P54860	UFD2_YEAST	E4 ubiquitin-protein ligase UFD2	10089879	A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly.

Q13835	PKP1_HUMAN	Plakophilin-1	9369526	Plakophilins 1a and 1b: widespread nuclear proteins recruited in specific epithelial cells as desmosomal plaque components.

Q6UVK1	CSPG4_HUMAN	Chondroitin sulfate proteoglycan 4	8790396	Molecular cloning of a human melanoma-associated chondroitin sulfate proteoglycan.

Q08754	BUD7_YEAST	Bud site selection protein 7	17000877	Exomer: a coat complex for transport of select membrane proteins from the trans-Golgi network to the plasma membrane in yeast.

Q02283	HAT5_ARATH	Homeobox-leucine zipper protein HAT5	16055682	Homeodomain leucine zipper class I genes in Arabidopsis. Expression patterns and phylogenetic relationships.

P55042	RAD_HUMAN	GTP-binding protein RAD	8248782	Rad: a member of the Ras family overexpressed in muscle of type II diabetic humans.

P27487	DPP4_HUMAN	Dipeptidyl peptidase 4	17549790	The Simpson-Golabi-Behmel syndrome causative glypican-3, binds to and inhibits the dipeptidyl peptidase activity of CD26.

Q9Y5W5	WIF1_HUMAN	Wnt inhibitory factor 1	10201374	A new secreted protein that binds to Wnt proteins and inhibits their activities.

P36619	PMD1_SCHPO	Leptomycin B resistance protein pmd1	1349418	A leptomycin B resistance gene of Schizosaccharomyces pombe encodes a protein similar to the mammalian P-glycoproteins.

Q6W5P4	NPSR1_HUMAN	Neuropeptide S receptor	15947423	Characterization of GPRA, a novel G protein-coupled receptor related to asthma.

Q54BD4	STATC_DICDI	Signal transducer and activator of transcription C	17517120	STATc is a key regulator of the transcriptional response to hyperosmotic shock.

Q08822	ETFD_YEAST	Probable electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

P60891	PRPS1_HUMAN	Ribose-phosphate pyrophosphokinase 1	16939420	Crystal structure of human phosphoribosylpyrophosphate synthetase 1 reveals a novel allosteric site.

Q9H093	NUAK2_HUMAN	NUAK family SNF1-like kinase 2	14575707	Induction of cell-cell detachment during glucose starvation through F-actin conversion by SNARK, the fourth member of the AMP-activated protein kinase catalytic subunit family.

Q06032	CST9_YEAST	Chromosome stability protein 9	15805472	Multiple branches of the meiotic recombination pathway contribute independently to homolog pairing and stable juxtaposition during meiosis in budding yeast.

P18886	CPT2_RAT	Carnitine O-palmitoyltransferase 2, mitochondrial	2355018	Cloning, sequencing, and expression of a cDNA encoding rat liver mitochondrial carnitine palmitoyltransferase II.

Q9SVC2	SY122_ARATH	Syntaxin-122	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

O08658	NUP88_RAT	Nuclear pore complex protein Nup88	9166401	Nup84, a novel nucleoporin that is associated with CAN/Nup214 on the cytoplasmic face of the nuclear pore complex.

Q60I26	AL2CL_MOUSE	ALS2 C-terminal-like protein	17239822	ALS2CL, a novel ALS2-interactor, modulates ALS2-mediated endosome dynamics.

O59740	MOD5P_SCHPO	Cell polarity protein mod5	12789340	Fission yeast mod5p regulates polarized growth through anchoring of tea1p at cell tips.

Q04666	HES1_RAT	Transcription factor HES-1	8687460	Molecular interaction between TLE1 and the carboxyl-terminal domain of HES-1 containing the WRPW motif.

O43909	EXTL3_HUMAN	Exostosin-like 3	10639137	The putative tumor suppressors EXT1 and EXT2 form a stable complex that accumulates in the Golgi apparatus and catalyzes the synthesis of heparan sulfate.

P80511	S10AC_HUMAN	Protein S100-A12	19386136	Both Ca2+ and Zn2+ are essential for S100A12 protein oligomerization and function.

Q8N612	F16A2_HUMAN	FTS and Hook-interacting protein	18799622	An FTS/Hook/p107(FHIP) complex interacts with and promotes endosomal clustering by the homotypic vacuolar protein sorting complex.

O42933	PMT4_SCHPO	Dolichyl-phosphate-mannose--protein mannosyltransferase 4	15809069	Characterization of O-mannosyltransferase family in Schizosaccharomyces pombe.

P77304	DTPA_ECOLI	Dipeptide and tripeptide permease A	17158458	Functional and structural characterization of a prokaryotic peptide transporter with features similar to mammalian PEPT1.

P22438	SYMM_YEAST	Methionyl-tRNA synthetase, mitochondrial	2645139	Characterization of MSM1, the structural gene for yeast mitochondrial methionyl-tRNA synthetase.

Q94F62	BAK1_ARATH	BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1	17626179	The receptor-like kinase SERK3/BAK1 is a central regulator of innate immunity in plants.

O94667	RTF1_SCHPO	RNA polymerase-associated protein C651.09c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P04426	WNT1_MOUSE	Proto-oncogene Wnt-1	2202907	Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development.

Q8IW19	APLF_HUMAN	Aprataxin and PNK-like factor	17353262	APLF (C2orf13) is a novel human protein involved in the cellular response to chromosomal DNA strand breaks.

Q42533	BCCP1_ARATH	Biotin carboxyl carrier protein of acetyl-CoA carboxylase 1, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

P32447	ASF1_YEAST	Histone chaperone ASF1	16303565	Replication-independent histone deposition by the HIR complex and Asf1.

Q62674	S28A1_RAT	Sodium/nucleoside cotransporter 1	8027026	Cloning and functional expression of a complementary DNA encoding a mammalian nucleoside transport protein.

Q06609	RAD51_HUMAN	DNA repair protein RAD51 homolog 1	7988572	Purification and characterization of the human Rad51 protein, an analogue of E. coli RecA.

Q8IUL8	CILP2_HUMAN	Cartilage intermediate layer protein 2	12746903	One of two chondrocyte-expressed isoforms of cartilage intermediate- layer protein functions as an insulin-like growth factor 1 antagonist.

P12630	BAR1_YEAST	Barrierpepsin	3124102	The Saccharomyces cerevisiae BAR1 gene encodes an exported protein with homology to pepsin.

Q62148	AL1A2_MOUSE	Retinal dehydrogenase 2	8797830	Molecular identification of a major retinoic-acid-synthesizing enzyme, a retinaldehyde-specific dehydrogenase.

P47061	VPS53_YEAST	Vacuolar protein sorting-associated protein 53	12620189	The ARF-like GTPases Arl1p and Arl3p act in a pathway that interacts with vesicle-tethering factors at the Golgi apparatus.

O94674	YG76_SCHPO	AFI1-like protein C776.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P13386	FCERB_RAT	High affinity immunoglobulin epsilon receptor subunit beta	2970642	Isolation and characterization of cDNAs coding for the beta subunit of the high-affinity receptor for immunoglobulin E.

P47168	TTI2_YEAST	TEL2-interacting protein 2	14562095	Global analysis of protein localization in budding yeast.

O74875	YJ83_SCHPO	Uncharacterized heme-binding protein C330.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q93WP7	HSYB_TOBAC	Hydroxyproline-rich systemin B	11459063	Production of multiple plant hormones from a single polyprotein precursor.

Q9UTM8	SSDH2_SCHPO	Putative succinate-semialdehyde dehydrogenase C139.05 [NADP+]	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P53692	SMC6_SCHPO	Structural maintenance of chromosomes protein 6	8524274	The rad18 gene of Schizosaccharomyces pombe defines a new subgroup of the SMC superfamily involved in DNA repair.

P30432	FUR2_DROME	Furin-like protease 2	1512259	Cloning and functional expression of Dfurin2, a subtilisin-like proprotein processing enzyme of Drosophila melanogaster with multiple repeats of a cysteine motif.

P10643	CO7_HUMAN	Complement component C7	3335508	The structure of human complement component C7 and the C5b-7 complex.

P41439	FOLR3_HUMAN	Folate receptor gamma	8110752	Identification of a novel folate receptor, a truncated receptor, and receptor type beta in hematopoietic cells: cDNA cloning, expression, immunoreactivity, and tissue specificity.

P20929	NEBU_HUMAN	Nebulin	7739042	The complete primary structure of human nebulin and its correlation to muscle structure.

Q7Z449	CP2U1_HUMAN	Cytochrome P450 2U1	14660610	CYP2U1, a novel human thymus- and brain-specific cytochrome P450, catalyzes omega- and (omega-1)-hydroxylation of fatty acids.

Q9BXS0	COPA1_HUMAN	Collagen alpha-1(XXV) chain	15522881	Characterization of the Alzheimer's disease-associated CLAC protein and identification of an amyloid beta-peptide-binding site.

P83282	CICD_CICFL	Cicadin	11814612	Isolation of cicadin, a novel and potent antifungal peptide from dried juvenile cicadas.

Q64727	VINC_MOUSE	Vinculin	10085297	Ponsin/SH3P12: an l-afadin- and vinculin-binding protein localized at cell-cell and cell-matrix adherens junctions.

B0F9L4	GOGC6_ARATH	Golgin candidate 6	18182439	Localization and domain characterization of Arabidopsis golgin candidates.

Q12234	RUD3_YEAST	GRIP domain-containing protein RUD3	10512869	High-copy suppressor analysis reveals a physical interaction between Sec34p and Sec35p, a protein implicated in vesicle docking.

Q9H6Q4	NARFL_HUMAN	Cytosolic Fe-S cluster assembly factor NARFL	18270200	A role for IOP1 in mammalian cytosolic iron-sulfur protein biogenesis.

Q9BSM1	PCGF1_HUMAN	Polycomb group RING finger protein 1	16943429	Polycomb group and SCF ubiquitin ligases are found in a novel BCOR complex that is recruited to BCL6 targets.

P49775	HNT2_YEAST	Bis(5'-adenosyl)-triphosphatase	14562095	Global analysis of protein localization in budding yeast.

Q76IC5	PGPI_RAT	Pyroglutamyl-peptidase 1	14600395	Hydrolysis of synthetic substrate, L-pyroglutamyl p-nitroanilide is catalyzed solely by pyroglutamyl aminopeptidase I in rat liver cytosol.

O00222	GRM8_HUMAN	Metabotropic glutamate receptor 8	9473604	Group III human metabotropic glutamate receptors 4, 7 and 8: molecular cloning, functional expression, and comparison of pharmacological properties in RGT cells.

Q07648	DTD_YEAST	D-tyrosyl-tRNA(Tyr) deacylase	10766779	D-tyrosyl-tRNA(Tyr) metabolism in Saccharomyces cerevisiae.

O00233	PSMD9_HUMAN	26S proteasome non-ATPase regulatory subunit 9	19490896	Assembly pathway of the Mammalian proteasome base subcomplex is mediated by multiple specific chaperones.

Q56WD9	THIK2_ARATH	3-ketoacyl-CoA thiolase 2, peroxisomal	11891244	Evidence supporting a role of jasmonic acid in Arabidopsis leaf senescence.

Q9LHG8	ELC_ARATH	Protein ELC	17090720	The Arabidopsis elch mutant reveals functions of an ESCRT component in cytokinesis.

Q9ZSY2	DNJ15_ARATH	Chaperone protein dnaJ 15	9927707	ARG1 (Altered Response to Gravity) encodes a novel DnaJ-like protein which potentially interacts with the cytoskeleton.

Q99469	STAC_HUMAN	SH3 and cysteine-rich domain-containing protein	8954993	Stac, a novel neuron-specific protein with cysteine-rich and SH3 domains.

Q10257	RRP8_SCHPO	Ribosomal RNA-processing protein 8	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12035	FCF2_YEAST	rRNA-processing protein FCF2	14562095	Global analysis of protein localization in budding yeast.

Q92769	HDAC2_HUMAN	Histone deacetylase 2	12140263	Daxx and histone deacetylase II associate with chromatin through an interaction with core histones and the chromatin-associated protein Dek.

Q90WZ1	KNL1B_BOMMX	Kininogen-1b	11500030	A novel bradykinin-related peptide from skin secretions of toad Bombina maxima and its precursor containing six identical copies of the final product.

P32488	MBR3_YEAST	Protein MBR3	8208248	MBR1 and MBR3, two related yeast genes that can suppress the growth defect of hap2, hap3 and hap4 mutants.

Q9ZU11	ATB15_ARATH	Homeobox-leucine zipper protein ATHB-15	15598805	Class III homeodomain-leucine zipper gene family members have overlapping, antagonistic, and distinct roles in Arabidopsis development.

P06104	UBC2_YEAST	Ubiquitin-conjugating enzyme E2 2	8436296	The extremely conserved amino terminus of RAD6 ubiquitin-conjugating enzyme is essential for amino-end rule-dependent protein degradation.

O60287	NPA1P_HUMAN	Nucleolar pre-ribosomal-associated protein 1	12429849	Functional proteomic analysis of human nucleolus.

Q96WV4	YHU5_SCHPO	UPF0641 membrane protein PJ4664.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P38426	TPS3_YEAST	Trehalose synthase complex regulatory subunit TPS3	9837904	Composition and functional analysis of the Saccharomyces cerevisiae trehalose synthase complex.

Q9LVR0	ATB53_ARATH	Homeobox-leucine zipper protein ATHB-53	15567172	Induction of a homeodomain-leucine zipper gene by auxin is inhibited by cytokinin in Arabidopsis roots.

O94531	UFE1_SCHPO	Syntaxin ufe1	14655046	Two-hybrid search for proteins that interact with Sad1 and Kms1, two membrane-bound components of the spindle pole body in fission yeast.

Q9BY66	KDM5D_HUMAN	Lysine-specific demethylase 5D	17320160	The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases.

P40856	SA185_YEAST	SIT4-associating protein SAP185	8649382	The SAPs, a new family of proteins, associate and function positively with the SIT4 phosphatase.

Q9LDU5	TI11A_ARATH	Protein TIFY 11A	20360743	NINJA connects the co-repressor TOPLESS to jasmonate signalling.

P15149	CP2A2_RAT	Cytochrome P450 2A2	2322568	Structure and in vitro transcription of the rat CYP2A1 and CYP2A2 genes and regional localization of the CYP2A gene subfamily on mouse chromosome 7.

O60671	RAD1_HUMAN	Cell cycle checkpoint protein RAD1	9660799	A human homologue of the Schizosaccharomyces pombe rad1+ checkpoint gene encodes an exonuclease.

Q8W493	FNRL2_ARATH	Ferredoxin--NADP reductase, leaf isozyme 2, chloroplastic	14729914	In-depth analysis of the thylakoid membrane proteome of Arabidopsis thaliana chloroplasts: new proteins, new functions, and a plastid proteome database.

Q9UTB3	YL85_SCHPO	Putative tRNA pseudouridine synthase C25B8.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O42342	SOX7_XENLA	Transcription factor Sox-7	17608734	The Sox axis, Nodal signaling, and germ layer specification.

O88898	P63_MOUSE	Tumor protein 63	10227294	p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development.

P12235	ADT1_HUMAN	ADP/ATP translocase 1	2823266	cDNA sequence of a human skeletal muscle ADP/ATP translocator: lack of a leader peptide, divergence from a fibroblast translocator cDNA, and coevolution with mitochondrial DNA genes.

O74827	CHO1_SCHPO	Methylene-fatty-acyl-phospholipid synthase	9755189	The Schizosaccharomyces pombe cho1+ gene encodes a phospholipid methyltransferase.

Q8K557	ONEC3_MOUSE	One cut domain family member 3	11944891	OC-3, a novel mammalian member of the ONECUT class of transcription factors.

Q9S9Q9	Y1044_ARATH	BTB/POZ domain-containing protein At1g30440	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

P35719	MRP8_YEAST	Uncharacterized protein MRP8	14562095	Global analysis of protein localization in budding yeast.

P61092	SIA1A_MOUSE	E3 ubiquitin-protein ligase SIAH1A	11884614	The ubiquitin ligase component Siah1a is required for completion of meiosis I in male mice.

Q9I8L5	FA10A_DANRE	Fatty acid-binding protein 10-A, liver basic	17670743	A single amino acid mutation in zebrafish (Danio rerio) liver bile acid-binding protein can change the stoichiometry of ligand binding.

P97879	GRIP1_RAT	Glutamate receptor-interacting protein 1	11931740	Interaction between GRIP and liprin-alpha/SYD2 is required for AMPA receptor targeting.

P27889	HNF1B_MOUSE	Hepatocyte nuclear factor 1-beta	1673925	LFB3, a heterodimer-forming homeoprotein of the LFB1 family, is expressed in specialized epithelia.

Q9XWD6	CED1_CAEEL	Cell death abnormality protein 1	15744306	Two pathways converge at CED-10 to mediate actin rearrangement and corpse removal in C. elegans.

O89043	DPOA2_RAT	DNA polymerase alpha subunit B	11536367	A mutation in subunit B of the DNA polymerase alpha-primase complex from Novikoff hepatoma cells concomitant with a conformational change and abnormal catalytic properties of the DNA polymerase alpha-primase complex.

Q9P7W4	POF10_SCHPO	F-box/WD repeat-containing protein pof10	15147268	Molecular interactions of fission yeast Skp1 and its role in the DNA damage checkpoint.

Q5G1S8	PP241_ARATH	Pentatricopeptide repeat-containing protein At3g18110, chloroplastic	15647901	Arabidopsis emb175 and other ppr knockout mutants reveal essential roles for pentatricopeptide repeat (PPR) proteins in plant embryogenesis.

Q04049	POLH_YEAST	DNA polymerase eta	16387871	The in vivo characterization of translesion synthesis across UV- induced lesions in Saccharomyces cerevisiae: insights into Pol zeta- and Pol eta-dependent frameshift mutagenesis.

P38789	SSF1_YEAST	Ribosome biogenesis protein SSF1	11864607	Ssf1p prevents premature processing of an early pre-60S ribosomal particle.

P83292	G23AB_DROME	Putative gustatory receptor 23a, isoform B	11516643	Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

Q9VXY7	LSD2_DROME	Lipid storage droplets surface-binding protein 2	14550535	Drosophila Perilipin/ADRP homologue Lsd2 regulates lipid metabolism.

Q06708	VAC14_YEAST	Vacuole morphology and inheritance protein 14	19037259	VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P(2) in yeast and mouse.

P04083	ANXA1_HUMAN	Annexin A1	2936963	Cloning and expression of human lipocortin, a phospholipase A2 inhibitor with potential anti-inflammatory activity.

P51955	NEK2_HUMAN	Serine/threonine-protein kinase Nek2	15161910	Nucleolar Nek11 is a novel target of Nek2A in G1/S-arrested cells.

O74558	MOB2_SCHPO	Maintenance of ploidy protein mob2	12456722	Mob2p interacts with the protein kinase Orb6p to promote coordination of cell polarity with cell cycle progression.

P10644	KAP0_HUMAN	cAMP-dependent protein kinase type I-alpha regulatory subunit	3426618	Molecular cloning, cDNA structure and deduced amino acid sequence for a type I regulatory subunit of cAMP-dependent protein kinase from human testis.

Q60520	SIN3A_MOUSE	Paired amphipathic helix protein Sin3a	9702189	SAP30, a component of the mSin3 corepressor complex involved in N- CoR-mediated repression by specific transcription factors.

Q9C0Y8	YKM6_SCHPO	UPF0613 protein PB24D3.06c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P30606	ITR2_YEAST	Myo-inositol transporter 2	2040626	Isolation and characterization of two distinct myo-inositol transporter genes of Saccharomyces cerevisiae.

P17735	ATTY_HUMAN	Tyrosine aminotransferase	1973834	Isolation and characterization of the human tyrosine aminotransferase gene.

P00797	RENI_HUMAN	Renin	16116425	Mutations in genes in the renin-angiotensin system are associated with autosomal recessive renal tubular dysgenesis.

Q8WTP8	AEN_HUMAN	Apoptosis-enhancing nuclease	16171785	Identification of a novel ionizing radiation-induced nuclease, AEN, and its functional characterization in apoptosis.

P55051	FABP7_RAT	Fatty acid-binding protein, brain	7931318	Cloning and characterization of a cDNA encoding a novel fatty acid binding protein from rat brain.

Q15056	IF4H_HUMAN	Eukaryotic translation initiation factor 4H	8812460	Identification of genes from a 500-kb region at 7q11.23 that is commonly deleted in Williams syndrome patients.

Q9T0K1	GBIS2_ARATH	(Z)-gamma-bisabolene synthase 2	16297850	Microarray expression profiling and functional characterization of AtTPS genes: duplicated Arabidopsis thaliana sesquiterpene synthase genes At4g13280 and At4g13300 encode root-specific and wound-inducible (Z)-gamma-bisabolene synthases.

Q6UVJ0	SAS6_HUMAN	Spindle assembly abnormal protein 6 homolog	17681131	Plk4-induced centriole biogenesis in human cells.

Q15554	TERF2_HUMAN	Telomeric repeat-binding factor 2	19596235	Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair.

Q9QYB2	DACH1_MOUSE	Dachshund homolog 1	12130660	Tissue-specific regulation of retinal and pituitary precursor cell proliferation.

P52286	SKP1_YEAST	Suppressor of kinetochore protein 1	9346238	F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex.

Q9ZPV8	COAD_ARATH	Phosphopantetheine adenylyltransferase	12860978	4'-phosphopantetheine and coenzyme A biosynthesis in plants.

Q7TNN9	RHCG_RAT	Ammonium transporter Rh type C	12595489	RhBG and RhCG, the putative ammonia transporters, are expressed in the same cells in the distal nephron.

Q9Y5E3	PCDB6_HUMAN	Protocadherin beta-6	10380929	A striking organization of a large family of human neural cadherin- like cell adhesion genes.

Q08491	SKI7_YEAST	Superkiller protein 7	12881429	Interaction between Ski7p and Upf1p is required for nonsense-mediated 3'-to-5' mRNA decay in yeast.

Q9UUH8	YKI4_SCHPO	Uncharacterized protein C630.04c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O48809	LRX2_ARATH	Leucine-rich repeat extensin-like protein 2	12834403	Synergistic interaction of the two paralogous Arabidopsis genes LRX1 and LRX2 in cell wall formation during root hair development.

P40554	URM1_YEAST	Ubiquitin-related modifier 1	18755837	A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae.

Q9USH9	YJQ1_SCHPO	Uncharacterized ABC transporter ATP-binding protein C825.01	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q941L0	CESA3_ARATH	Cellulose synthase A catalytic subunit 3 [UDP-forming]	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

Q8CGK3	LONM_MOUSE	Lon protease homolog, mitochondrial	12657466	The ATP-dependent Lon protease of Mus musculus is a DNA-binding protein that is functionally conserved between yeast and mammals.

O15182	CETN3_HUMAN	Centrin-3	9256449	Identification of a new mammalian centrin gene, more closely related to Saccharomyces cerevisiae CDC31 gene.

O74337	YH24_SCHPO	Uncharacterized protein C1A4.04	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q27452	PRP2_BOMMO	Phenoloxidase subunit 2	7644494	Molecular cloning of insect pro-phenol oxidase: a copper-containing protein homologous to arthropod hemocyanin.

Q61831	MK10_MOUSE	Mitogen-activated protein kinase 10	10471813	A novel Jun N-terminal kinase (JNK)-binding protein that enhances the activation of JNK by MEK kinase 1 and TGF-beta-activated kinase 1.

O43889	CREB3_HUMAN	Cyclic AMP-responsive element-binding protein 3	15705566	Zhangfei is a potent and specific inhibitor of the host cell factor- binding transcription factor Luman.

P38265	IML3_YEAST	Central kinetochore subunit IML3	11361335	The IML3/MCM19 gene of Saccharomyces cerevisiae is required for a kinetochore-related process during chromosome segregation.

Q53HL2	BOREA_HUMAN	Borealin	18243099	Mps1 phosphorylates Borealin to control Aurora B activity and chromosome alignment.

Q8GXW1	RGL2_ARATH	DELLA protein RGL2	16167898	Identification of the conserved serine/threonine residues important for gibberellin-sensitivity of Arabidopsis RGL2 protein.

P0A8R9	HDFR_ECOLI	HTH-type transcriptional regulator hdfR	10913108	H-NS-dependent regulation of flagellar synthesis is mediated by a LysR family protein.

Q8JFY4	GHRL_ANGJA	Ghrelin	12630926	Amidated fish ghrelin: purification, cDNA cloning in the Japanese eel and its biological activity.

P0C2S1	CELK_CLOTM	Cellulose 1,4-beta-cellobiosidase	10464199	Cloning and sequence analysis of a new cellulase gene encoding CelK, a major cellulosome component of Clostridium thermocellum: evidence for gene duplication and recombination.

P28360	MSX1_HUMAN	Homeobox protein MSX-1	8696335	A human MSX1 homeodomain missense mutation causes selective tooth agenesis.

P83148	MEFP_MYTED	Major extrapallial fluid protein	11084027	Purification and characterization of a novel calcium-binding protein from the extrapallial fluid of the mollusc, Mytilus edulis.

P47108	URB2_YEAST	Nucleolar pre-ribosomal-associated protein 2	15226434	Npa1p, a component of very early pre-60S ribosomal particles, associates with a subset of small nucleolar RNPs required for peptidyl transferase center modification.

Q63635	STX6_RAT	Syntaxin-6	10506127	The Rab5 effector EEA1 interacts directly with syntaxin-6.

Q15131	CDK10_HUMAN	Cell division protein kinase 10	8208557	PISSLRE, a human novel CDC2-related protein kinase.

Q96F86	EDC3_HUMAN	Enhancer of mRNA-decapping protein 3	16364915	Multiple processing body factors and the ARE binding protein TTP activate mRNA decapping.

Q96529	PURA_ARATH	Adenylosuccinate synthetase, chloroplastic	8790347	The mode of action and the structure of a herbicide in complex with its target: binding of activated hydantocidin to the feedback regulation site of adenylosuccinate synthetase.

P21744	IBP4_RAT	Insulin-like growth factor-binding protein 4	7679899	Structure of the rat insulin-like growth factor binding protein-4 gene.

P39113	CAT8_YEAST	Regulatory protein CAT8	7891685	CAT8, a new zinc cluster-encoding gene necessary for derepression of gluconeogenic enzymes in the yeast Saccharomyces cerevisiae.

Q9UBF9	MYOTI_HUMAN	Myotilin	10958653	Myotilin is mutated in limb girdle muscular dystrophy 1A.

P40165	YNU0_YEAST	Uncharacterized protein YNL200C	14562095	Global analysis of protein localization in budding yeast.

P11309	PIM1_HUMAN	Proto-oncogene serine/threonine-protein kinase pim-1	18593906	Pim kinases promote cell cycle progression by phosphorylating and down-regulating p27Kip1 at the transcriptional and posttranscriptional levels.

Q92731	ESR2_HUMAN	Estrogen receptor beta	9671811	Molecular cloning and characterization of human estrogen receptor beta cx: a potential inhibitor of estrogen action in human.

Q09122	SCRB_FUSMR	Sucrose-6-phosphate hydrolase	1533618	Sucrose fermentation by Fusobacterium mortiferum ATCC 25557: transport, catabolism, and products.

P30411	BKRB2_HUMAN	B2 bradykinin receptor	7835885	Structure and chromosomal localization of the gene (BDKRB2) encoding human bradykinin B2 receptor.

P42945	UTP10_YEAST	U3 small nucleolar RNA-associated protein 10	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q8CBB9	RSAD2_MOUSE	Radical S-adenosyl methionine domain-containing protein 2	17686841	Identification and characterization of interferon-induced proteins that inhibit alphavirus replication.

Q27564	KITH_DICDI	Thymidine kinase 1	15883042	Isolation and characterization of Dictyostelium thymidine kinase 1 as a calmodulin-binding protein.

Q21193	PROF3_CAEEL	Profilin-3	16317718	Caenorhabditis elegans expresses three functional profilins in a tissue-specific manner.

P80201	ACVR1_RAT	Activin receptor type-1	8248234	Cloning and characterization of a transmembrane serine kinase that acts as an activin type I receptor.

P18409	MDM10_YEAST	Mitochondrial distribution and morphology protein 10	19556461	An ER-mitochondria tethering complex revealed by a synthetic biology screen.

P47030	TAX4_YEAST	Protein TAX4	15265867	Negative regulation of phosphatidylinositol 4,5-bisphosphate levels by the INP51-associated proteins TAX4 and IRS4.

Q8C0L6	PAOX_MOUSE	Peroxisomal N(1)-acetyl-spermine/spermidine oxidase	12660232	Cloning, sequencing, and heterologous expression of the murine peroxisomal flavoprotein, N(1)-acetylated polyamine oxidase.

Q9P0U4	CXXC1_HUMAN	CpG-binding protein	17355966	Identification and characterization of the human Set1B histone H3- Lys4 methyltransferase complex.

Q9UBC3	DNM3B_HUMAN	DNA (cytosine-5)-methyltransferase 3B	11735126	Dnmt3b, de novo DNA methyltransferase, interacts with SUMO-1 and Ubc9 through its N-terminal region and is subject to modification by SUMO- 1.

O15379	HDAC3_HUMAN	Histone deacetylase 3	19409814	NKAP is a transcriptional repressor of notch signaling and is required for T cell development.

P25348	RM32_YEAST	54S ribosomal protein L32, mitochondrial	2060626	Extended N-terminal sequencing of proteins of the large ribosomal subunit from yeast mitochondria.

O14170	POP2_SCHPO	WD repeat-containing protein pop2	9653157	sud1+ targets cyclin-dependent kinase-phosphorylated Cdc18 and Rum1 proteins for degradation and stops unwanted diploidization in fission yeast.

Q03497	STE20_YEAST	Serine/threonine-protein kinase STE20	15652479	Sterile 20 kinase phosphorylates histone H2B at serine 10 during hydrogen peroxide-induced apoptosis in S. cerevisiae.

Q14141	SEPT6_HUMAN	Septin-6	11809673	SEPTIN6, a human homologue to mouse Septin6, is fused to MLL in infant acute myeloid leukemia with complex chromosomal abnormalities involving 11q23 and Xq24.

Q9Y262	EIF3L_HUMAN	Eukaryotic translation initiation factor 3 subunit L	17581632	Reconstitution reveals the functional core of mammalian eIF3.

O22467	MSI1_ARATH	WD-40 repeat-containing protein MSI1	12970192	Arabidopsis MSI1 is a component of the MEA/FIE Polycomb group complex and required for seed development.

P17342	ANPRC_HUMAN	Atrial natriuretic peptide receptor 3	1660465	Extracellular domain-IgG fusion proteins for three human natriuretic peptide receptors. Hormone pharmacology and application to solid phase screening of synthetic peptide antisera.

P61254	RL26_HUMAN	60S ribosomal protein L26	8479925	Sequence of a cDNA encoding human ribosomal protein L26 and of a cDNA probably encoding human ribosomal protein L6.

P37013	NORR_ECOLI	Anaerobic nitric oxide reductase transcription regulator norR	12529359	Regulation of the nitric oxide reduction operon (norRVW) in Escherichia coli: role of NorR and sigma 54 in the nitric oxide stress response.

P40486	SHQ1_YEAST	Protein SHQ1	12228251	The Shq1p.Naf1p complex is required for box H/ACA small nucleolar ribonucleoprotein particle biogenesis.

Q12241	VAM3_YEAST	Syntaxin VAM3	9245783	A multispecificity syntaxin homologue, Vam3p, essential for autophagic and biosynthetic protein transport to the vacuole.

P08631	HCK_HUMAN	Tyrosine-protein kinase HCK	3453117	Novel protein-tyrosine kinase gene (hck) preferentially expressed in cells of hematopoietic origin.

Q24185	HOOK_DROME	Protein hook	17435236	Genetic modifiers of the Drosophila blue cheese gene link defects in lysosomal transport with decreased life span and altered ubiquitinated-protein profiles.

Q05022	RRP5_YEAST	rRNA biogenesis protein RRP5	12068309	A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis.

O70572	NSMA_MOUSE	Sphingomyelin phosphodiesterase 2	15764706	Neutral sphingomyelinase 2 (smpd3) in the control of postnatal growth and development.

Q05015	FSH2_YEAST	Family of serine hydrolases 2	14562095	Global analysis of protein localization in budding yeast.

Q8VHP6	CDHR1_MOUSE	Cadherin-related family member 1	11738025	A photoreceptor-specific cadherin is essential for the structural integrity of the outer segment and for photoreceptor survival.

Q9VB26	GR98B_DROME	Putative gustatory receptor 98b	10710312	Candidate taste receptors in Drosophila.

P48546	GIPR_HUMAN	Gastric inhibitory polypeptide receptor	7556958	Cloning, functional expression, and chromosomal localization of the human pancreatic islet glucose-dependent insulinotropic polypeptide receptor.

Q5W7F2	AGD3_ARATH	ADP-ribosylation factor GTPase-activating protein AGD3	10887077	The SCARFACE gene is required for cotyledon and leaf vein patterning.

Q9XTL9	PYG_DROME	Glycogen phosphorylase	10092506	Structural and functional characterization of the Drosophila glycogen phosphorylase gene.

P25574	EMC1_YEAST	ER membrane protein complex subunit 1	19325107	Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum.

Q9UHD2	TBK1_HUMAN	Serine/threonine-protein kinase TBK1	10581243	NF-kB activation by a signaling complex containing TRAF2, TANK, and TBK1, a novel IKK-related kinase.

P30408	T4S1_HUMAN	Transmembrane 4 L6 family member 1	7510285	Membrane topology of the L6 antigen and identification of the protein epitope recognized by the L6 monoclonal antibody.

P52298	NCBP2_HUMAN	Nuclear cap-binding protein subunit 2	18369367	NMD resulting from encephalomyocarditis virus IRES-directed translation initiation seems to be restricted to CBP80/20-bound mRNA.

P62875	RPAB5_HUMAN	DNA-directed RNA polymerases I, II, and III subunit RPABC5	9852112	Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.

P40851	AXL1_YEAST	Putative protease AXL1	7990931	A yeast gene necessary for bud-site selection encodes a protein similar to insulin-degrading enzymes.

Q55BM4	TCPA_DICDI	T-complex protein 1 subunit alpha	9630545	A Dictyostelium discoideum homologue to Tcp-1 is essential for growth and development.

O14908	GIPC1_HUMAN	PDZ domain-containing protein GIPC1	9770488	GIPC, a PDZ domain containing protein, interacts specifically with the C-terminus of RGS-GAIP.

Q04752	STF1_BOVIN	Steroidogenic factor 1	8463279	Ad4BP regulating steroidogenic P-450 gene is a member of steroid hormone receptor superfamily.

P40310	TOK1_YEAST	Outward-rectifier potassium channel TOK1	7651518	A new family of outwardly rectifying potassium channel proteins with two pore domains in tandem.

Q9Y2A7	NCKP1_HUMAN	Nck-associated protein 1	10673335	Molecular cloning of a novel apoptosis-related gene, human Nap1 (NCKAP1), and its possible relation to Alzheimer disease.

Q75JK0	ZAKA_DICDI	Dual specificity protein kinase zakA	10571182	The novel tyrosine kinase ZAK1 activates GSK3 to direct cell fate specification.

O09106	HDAC1_MOUSE	Histone deacetylase 1	10615135	DNA methyltransferase Dnmt1 associates with histone deacetylase activity.

P15149	CP2A2_RAT	Cytochrome P450 2A2	3192524	Gene conversion and differential regulation in the rat P-450 IIA gene subfamily. Purification, catalytic activity, cDNA and deduced amino acid sequence, and regulation of an adult male-specific hepatic testosterone 15 alpha-hydroxylase.

Q9L4Q7	PROX_CLOST	Prolyl-tRNA editing protein proX	15886196	The bacterial YbaK protein is a Cys-tRNAPro and Cys-tRNA Cys deacylase.

O60841	IF2P_HUMAN	Eukaryotic translation initiation factor 5B	10200264	Universal conservation in translation initiation revealed by human and archaeal homologs of bacterial translation initiation factor IF2.

Q12341	HAT1_YEAST	Histone acetyltransferase type B catalytic subunit	9575221	HAT1 and HAT2 proteins are components of a yeast nuclear histone acetyltransferase enzyme specific for free histone H4.

P62258	1433E_HUMAN	14-3-3 protein epsilon	19172738	Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein.

O01367	HOW_DROME	Protein held out wings	9169854	The held out wings (how) Drosophila gene encodes a putative RNA- binding protein involved in the control of muscular and cardiac activity.

O74363	YND2_SCHPO	G-patch and R3H domain-containing protein C30B4.02c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P64530	RCNR_ECOLI	Transcriptional repressor rcnR	16956381	Nickel homeostasis in Escherichia coli - the rcnR-rcnA efflux pathway and its linkage to NikR function.

P30101	PDIA3_HUMAN	Protein disulfide-isomerase A3	7487104	cDNA cloning and baculovirus expression of the human liver endoplasmic reticulum P58: characterization as a protein disulfide isomerase isoform, but not as a protease or a carnitine acyltransferase.

P38958	PT100_YEAST	Protein PET100, mitochondrial	8702496	Cloning and characterization of PET100, a gene required for the assembly of yeast cytochrome c oxidase.

Q9NRX4	PHP14_HUMAN	14 kDa phosphohistidine phosphatase	12383260	Identification and characterization of a mammalian 14-kDa phosphohistidine phosphatase.

P77398	ARNA_ECOLI	Bifunctional polymyxin resistance protein ArnA	15807526	Crystal structure and mechanism of the Escherichia coli ArnA (PmrI) transformylase domain. An enzyme for lipid A modification with 4- amino-4-deoxy-L-arabinose and polymyxin resistance.

Q8K3I4	MYRIP_MOUSE	Rab effector MyRIP	11964381	MyRIP, a novel Rab effector, enables myosin VIIa recruitment to retinal melanosomes.

Q90415	RXRAB_DANRE	Retinoic acid receptor RXR-alpha-B	7565671	New retinoid X receptor subtypes in zebra fish (Danio rerio) differentially modulate transcription and do not bind 9-cis retinoic acid.

P24279	MCM3_YEAST	DNA replication licensing factor MCM3	15023545	Saccharomyces cerevisiae CSM1 gene encoding a protein influencing chromosome segregation in meiosis I interacts with elements of the DNA replication complex.

Q9URT4	AMS2_SCHPO	CENP-A multicopy suppressor protein 2	12535531	A cell cycle-regulated GATA factor promotes centromeric localization of CENP-A in fission yeast.

Q9M6N7	AMT2_ARATH	Ammonium transporter 2	12481062	Characterization of Arabidopsis AtAMT2, a high-affinity ammonium transporter of the plasma membrane.

Q9FF41	PMI15_ARATH	Protein PLASTID MOVEMENT IMPAIRED 15	16778016	Plastid movement impaired 2, a new gene involved in normal blue- light-induced chloroplast movements in Arabidopsis.

P53678	AP3M2_RAT	AP-3 complex subunit mu-2	8076832	Two rat homologs of clathrin-associated adaptor proteins.

Q00688	FKBP3_HUMAN	Peptidyl-prolyl cis-trans isomerase FKBP3	1374240	cDNA cloning of a human 25 kDa FK506 and rapamycin binding protein.

P42841	PFS2_YEAST	Polyadenylation factor subunit 2	12819204	Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-ends.

Q8CFM6	STAB2_RAT	Stabilin-2	12181351	Molecular cloning and functional expression of the rat 175-kDa hyaluronan receptor for endocytosis.

P09544	WNT2_HUMAN	Protein Wnt-2	2971536	Isolation of a human gene with protein sequence similarity to human and murine int-1 and the Drosophila segment polarity mutant wingless.

Q10038	VHP1_CAEEL	Tyrosine-protein phosphatase vhp-1	15116070	The Caenorhabditis elegans MAPK phosphatase VHP-1 mediates a novel JNK-like signaling pathway in stress response.

Q9UNN5	FAF1_HUMAN	FAS-associated factor 1	10462485	Identification and characterization of human Fas associated factor 1, hFAF1.

Q02094	RHAG_HUMAN	Ammonium transporter Rh type A	11062476	The human Rhesus-associated RhAG protein and a kidney homologue promote ammonium transport in yeast.

P21816	CDO1_RAT	Cysteine dioxygenase type 1	2334417	Isolation and characterization of a cDNA for rat liver cysteine dioxygenase.

P42704	LPPRC_HUMAN	Leucine-rich PPR motif-containing protein, mitochondrial	15907802	Putative tumor suppressor RASSF1 interactive protein and cell death inducer C19ORF5 is a DNA binding protein.

P38428	CUE1_YEAST	Coupling of ubiquitin conjugation to ER degradation protein 1	16873066	Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins.

O75900	MMP23_HUMAN	Matrix metalloproteinase-23	9988691	Cloning and characterization of human MMP-23, a new matrix metalloproteinase predominantly expressed in reproductive tissues and lacking conserved domains in other family members.

Q8QGC4	PBX1_XENLA	Pre-B-cell leukemia transcription factor 1	11960001	Xpbx1b and Xmeis1b play a collaborative role in hindbrain and neural crest gene expression in Xenopus embryos.

Q9BXP5	SRRT_HUMAN	Serrate RNA effector molecule homolog	19632182	Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation.

Q8BR76	MKS3_MOUSE	Meckelin	19515853	Ciliary and centrosomal defects associated with mutation and depletion of the Meckel syndrome genes MKS1 and MKS3.

Q96329	ACOX4_ARATH	Acyl-coenzyme A oxidase 4, peroxisomal	10212254	A novel acyl-CoA oxidase that can oxidize short-chain acyl-CoA in plant peroxisomes.

Q16827	PTPRO_HUMAN	Receptor-type tyrosine-protein phosphatase O	7665166	Molecular cloning of cDNAs encoding human GLEPP1, a membrane protein tyrosine phosphatase: characterization of the GLEPP1 protein distribution in human kidney and assignment of the GLEPP1 gene to human chromosome 12p12-p13.

P19474	RO52_HUMAN	E3 ubiquitin-protein ligase TRIM21	18845142	The autoantigen Ro52 is an E3 ligase resident in the cytoplasm but enters the nucleus upon cellular exposure to nitric oxide.

P90971	TBX12_CAEEL	T-box protein 12	10716947	The Caenorhabditis elegans fate-determining gene mab-9 encodes a T- box protein required to pattern the posterior hindgut.

Q80UE6	WNK4_MOUSE	Serine/threonine-protein kinase WNK4	12671053	WNK kinases regulate thiazide-sensitive Na-Cl cotransport.

O00300	TR11B_HUMAN	Tumor necrosis factor receptor superfamily member 11B	9108485	Osteoprotegerin: a novel secreted protein involved in the regulation of bone density.

Q9NDJ2	DOM_DROME	Helicase domino	16508010	Nipped-A, the Tra1/TRRAP subunit of the Drosophila SAGA and Tip60 complexes, has multiple roles in Notch signaling during wing development.

Q969H4	CNKR1_HUMAN	Connector enhancer of kinase suppressor of ras 1	9814705	CNK, a RAF-binding multidomain protein required for RAS signaling.

Q9UBN4	TRPC4_HUMAN	Short transient receptor potential channel 4	16254212	Activation of the endothelial store-operated ISOC Ca2+ channel requires interaction of protein 4.1 with TRPC4.

Q06408	ARO10_YEAST	Transaminated amino acid decarboxylase	14562095	Global analysis of protein localization in budding yeast.

Q6A037	N4BP1_MOUSE	NEDD4-binding protein 1	17592138	The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch.

A1XGB4	PIMP1_CAPAN	UPF0497 membrane protein PIMP1	18506481	Distinct roles of the pepper pathogen-induced membrane protein gene CaPIMP1 in bacterial disease resistance and oomycete disease susceptibility.

P85056	BR1SE_RANSV	Brevinin-1SE	16386333	Histamine-releasing and antimicrobial peptides from the skin secretions of the dusky gopher frog, Rana sevosa.

P41833	IME4_YEAST	N6-adenosine-methyltransferase IME4	1545790	IME4, a gene that mediates MAT and nutritional control of meiosis in Saccharomyces cerevisiae.

Q22492	HEXA_CAEEL	Beta-hexosaminidase A	17636254	Biosynthesis of truncated N-linked oligosaccharides results from non- orthologous hexosaminidase-mediated mechanisms in nematodes, plants and insects.

P0ACU5	FABR_ECOLI	HTH-type transcriptional repressor fabR	11859088	The FabR (YijC) transcription factor regulates unsaturated fatty acid biosynthesis in Escherichia coli.

O14227	RDR1_SCHPO	RNA-dependent RNA polymerase 1	15607976	Two RNAi complexes, RITS and RDRC, physically interact and localize to noncoding centromeric RNAs.

Q9P289	MST4_HUMAN	Serine/threonine-protein kinase MST4	17360971	PDCD10 interacts with Ste20-related kinase MST4 to promote cell growth and transformation via modulation of the ERK pathway.

P02843	VIT1_DROME	Vitellogenin-1	3922974	Tyrosine sulfation of yolk proteins 1, 2, and 3 in Drosophila melanogaster.

P39007	STT3_YEAST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3	15831493	Subunits of the translocon interact with components of the oligosaccharyl transferase complex.

P42771	CD2A1_HUMAN	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3	8259215	A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4.

Q96A54	ADR1_HUMAN	Adiponectin receptor protein 1	12802337	Cloning of adiponectin receptors that mediate antidiabetic metabolic effects.

Q91V37	VATO_MOUSE	V-type proton ATPase 21 kDa proteolipid subunit	11441017	Expression and localization of the mouse homolog of the yeast V- ATPase 21-kDa subunit c' (Vma16p).

Q9SAR0	1A16_ARATH	1-aminocyclopropane-1-carboxylate synthase 6	12968022	Biochemical diversity among the 1-amino-cyclopropane-1-carboxylate synthase isozymes encoded by the Arabidopsis gene family.

P17084	COL_RAT	Colipase	2129524	Rat pancreatic colipase mRNA: nucleotide sequence of a cDNA clone and nutritional regulation by a lipidic diet.

P11021	GRP78_HUMAN	78 kDa glucose-regulated protein	18264092	OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD.

Q13207	TBX2_HUMAN	T-box transcription factor TBX2	8530034	Cloning and mapping of a human gene (TBX2) sharing a highly conserved protein motif with the Drosophila omb gene.

P02819	OSTCN_MACFA	Osteocalcin	6978733	Primary structure of monkey osteocalcin.

Q9WTQ2	PODXL_RAT	Podocalyxin	10982412	Expression of podocalyxin inhibits cell-cell adhesion and modifies junctional properties in Madin-Darby canine kidney cells.

O14258	ACE2_SCHPO	Metallothionein expression activator	12665550	The endo-beta-1,3-glucanase eng1p is required for dissolution of the primary septum during cell separation in Schizosaccharomyces pombe.

Q9S7I3	NLTP2_ARATH	Non-specific lipid-transfer protein 2	10940464	Lipid transfer proteins are encoded by a small multigene family in Arabidopsis thaliana.

P17255	VATA_YEAST	V-type proton ATPase catalytic subunit A	1534148	Homing of a DNA endonuclease gene by meiotic gene conversion in Saccharomyces cerevisiae.

Q8N3Y7	RDHE2_HUMAN	Epidermal retinol dehydrogenase 2	18926804	Biochemical characterization of human epidermal retinol dehydrogenase 2.

Q8BRB7	MYST4_MOUSE	Histone acetyltransferase MYST4	10821753	Querkopf, a MYST family histone acetyltransferase, is required for normal cerebral cortex development.

Q00610	CLH1_HUMAN	Clathrin heavy chain 1	1765375	Human clathrin heavy chain (CLTC): partial molecular cloning, expression, and mapping of the gene to human chromosome 17q11-qter.

B6EU02	JBP2_LEITA	Bifunctional helicase and thymine dioxygenase JBP2	19114062	Evidence that J-binding protein 2 is a thymidine hydroxylase catalyzing the first step in the biosynthesis of DNA base J.

O80592	AAP8_ARATH	Amino acid permease 8	12244056	High affinity amino acid transporters specifically expressed in xylem parenchyma and developing seeds of Arabidopsis.

P38247	SLM4_YEAST	Protein SLM4	16732272	A conserved GTPase-containing complex is required for intracellular sorting of the general amino-acid permease in yeast.

Q9H2H9	S38A1_HUMAN	Sodium-coupled neutral amino acid transporter 1	10891391	Cloning and functional expression of ATA1, a subtype of amino acid transporter A, from human placenta.

Q9P2N7	KLH13_HUMAN	Kelch-like protein 13	17543862	A Cul3-based E3 ligase removes Aurora B from mitotic chromosomes, regulating mitotic progression and completion of cytokinesis in human cells.

P61968	LMO4_HUMAN	LIM domain transcription factor LMO4	10209267	Molecular cloning of LMO4, a new human LIM domain gene.

Q9M1X5	ASK13_ARATH	SKP1-like protein 13	19682297	An F-box gene, CPR30, functions as a negative regulator of the defense response in Arabidopsis.

Q9PRJ8	FXD5A_XENLA	Forkhead box protein D5-A	11401404	foxD5a, a Xenopus winged helix gene, maintains an immature neural ectoderm via transcriptional repression that is dependent on the C- terminal domain.

P62942	FKB1A_HUMAN	Peptidyl-prolyl cis-trans isomerase FKBP1A	2477715	A receptor for the immunosuppressant FK506 is a cis-trans peptidyl- prolyl isomerase.

Q38897	BEL1_ARATH	Homeobox protein BEL1 homolog	11701881	The Arabidopsis BELL1 and KNOX TALE homeodomain proteins interact through a domain conserved between plants and animals.

Q794E4	HNRPF_RAT	Heterogeneous nuclear ribonucleoprotein F	10471789	Association of the rat heterogeneous nuclear RNA-ribonucleoprotein F with TATA-binding protein.

Q99674	CGRE1_HUMAN	Cell growth regulator with EF hand domain protein 1	8968090	Induction of cell growth regulatory genes by p53.

Q8LEU3	NOL_ARATH	Chlorophyll(ide) b reductase NOL, chloroplastic	19403948	Participation of chlorophyll b reductase in the initial step of the degradation of light-harvesting chlorophyll a/b-protein complexes in Arabidopsis.

P42752	CCD21_ARATH	Cyclin-D2-1	10848578	Sugar control of the plant cell cycle: differential regulation of Arabidopsis D-type cyclin gene expression.

P83917	CBX1_MOUSE	Chromobox protein homolog 1	10562550	Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family.

Q70J99	UN13D_HUMAN	Protein unc-13 homolog D	15548590	Munc13-4 is an effector of rab27a and controls secretion of lysosomes in hematopoietic cells.

P28817	HIBCH_YEAST	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q8RWN0	ULP1C_ARATH	Ubiquitin-like-specific protease 1C	18849491	Small ubiquitin-like modifier proteases OVERLY TOLERANT TO SALT1 and -2 regulate salt stress responses in Arabidopsis.

Q9HD42	CHM1A_HUMAN	Charged multivesicular body protein 1a	8863740	Molecular cloning, expression and chromosomal localization of a human gene encoding a 33 kDa putative metallopeptidase (PRSM1).

Q10752	CDC28_SCHPO	Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein cdc28	9003295	Isolation of novel pre-mRNA splicing mutants of Schizosaccharomyces pombe.

P32523	PRP19_YEAST	Pre-mRNA-splicing factor 19	12627222	Structural insights into the U-box, a domain associated with multi- ubiquitination.

O13816	SCC3_SCHPO	Cohesin subunit psc3	11069892	Characterization of fission yeast cohesin: essential anaphase proteolysis of Rad21 phosphorylated in the S phase.

P0CB49	YLPM1_RAT	YLP motif-containing protein 1	17890166	The nuclear PP1 interacting protein ZAP3 (ZAP) is a putative nucleoside kinase that complexes with SAM68, CIA, NF110/45, and HNRNP- G.

Q9VWV9	PORCN_DROME	Protein-cysteine N-palmitoyltransferase porcupine	8985181	The segment polarity gene porcupine encodes a putative multitransmembrane protein involved in Wingless processing.

O81439	PAP1_ARATH	Probable plastid-lipid-associated protein 1, chloroplastic	16461379	Protein profiling of plastoglobules in chloroplasts and chromoplasts. A surprising site for differential accumulation of metabolic enzymes.

Q56WH4	HDT2_ARATH	Histone deacetylase HDT2	18433157	Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.

P49137	MAPK2_HUMAN	MAP kinase-activated protein kinase 2	8280084	The substrate specificity and structure of mitogen-activated protein (MAP) kinase-activated protein kinase-2.

P38349	UBX7_YEAST	UBX domain-containing protein 7	14562095	Global analysis of protein localization in budding yeast.

Q5JRA6	MIA3_HUMAN	Melanoma inhibitory activity protein 3	19269366	TANGO1 facilitates cargo loading at endoplasmic reticulum exit sites.

O95292	VAPB_HUMAN	Vesicle-associated membrane protein-associated protein B/C	15372378	A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis.

P00519	ABL1_HUMAN	Tyrosine-protein kinase ABL1	11374898	Cloning, mapping, and characterization of the human sorbin and SH3 domain containing 1 (SORBS1) gene: a protein associated with c-Abl during insulin signaling in the hepatoma cell line Hep3B.

Q12029	FSF1_YEAST	Probable mitochondrial transport protein FSF1	14562095	Global analysis of protein localization in budding yeast.

Q9URU2	DNA2_SCHPO	DNA replication ATP-dependent helicase dna2	10880469	Genetic analyses of Schizosaccharomyces pombe dna2+ reveal that dna2 plays an essential role in Okazaki fragment metabolism.

Q46856	YQHD_ECOLI	Alcohol dehydrogenase yqhD	15327949	Crystal structure of E.coli alcohol dehydrogenase YqhD: evidence of a covalently modified NADP coenzyme.

Q9Y6Q9	NCOA3_HUMAN	Nuclear receptor coactivator 3	11971985	Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) coactivator activity by I kappa B kinase.

Q9Y7U3	GEP4_SCHPO	Probable phosphatidylglycerophosphatase, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P32561	RPD3_YEAST	Histone deacetylase RPD3	9512514	Histone deacetylase activity of Rpd3 is important for transcriptional repression in vivo.

Q12059	ULA1_YEAST	NEDD8-activating enzyme E1 regulatory subunit	9545234	A novel protein modification pathway related to the ubiquitin system.

Q54C92	CSN6_DICDI	COP9 signalosome complex subunit 6	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

P32841	RE114_YEAST	Meiotic recombination protein REC114	16783010	Saccharomyces cerevisiae Mer2, Mei4 and Rec114 form a complex required for meiotic double-strand break formation.

Q9USX7	PPK22_SCHPO	Serine/threonine-protein kinase ppk22	15821139	Systematic deletion analysis of fission yeast protein kinases.

O44476	RNZ_CAEEL	Ribonuclease Z	14729485	The Caenorhabditis elegans homolog of the putative prostate cancer susceptibility gene ELAC2, hoe-1, plays a role in germline proliferation.

P11277	SPTB1_HUMAN	Spectrin beta chain, erythrocyte	8226774	Spectrin Cagliari: an Ala-->Gly substitution in helix 1 of beta spectrin repeat 17 that severely disrupts the structure and self- association of the erythrocyte spectrin heterodimer.

P24100	CDKA1_ARATH	Cyclin-dependent kinase A-1	12857813	Arabidopsis D-type cyclin CYCD4;1 is a novel cyclin partner of B2- type cyclin-dependent kinase.

P36970	GPX41_RAT	Phospholipid hydroperoxide glutathione peroxidase, mitochondrial	8749327	Molecular cloning and functional expression of a cDNA for rat phospholipid hydroperoxide glutathione peroxidase: 3'-untranslated region of the gene is necessary for functional expression.

P01011	AACT_HUMAN	Alpha-1-antichymotrypsin	8647626	Characterisation of the tumour-associated carbohydrate epitope recognised by monoclonal antibody 4D3.

Q61180	SCNNA_MOUSE	Amiloride-sensitive sodium channel subunit alpha	10409305	Cloning and functional expression of the mouse epithelial sodium channel.

Q9FV53	DEF1A_ARATH	Peptide deformylase 1A, chloroplastic	11060042	Identification of eukaryotic peptide deformylases reveals universality of N-terminal protein processing mechanisms.

Q9UBC3	DNM3B_HUMAN	DNA (cytosine-5)-methyltransferase 3B	18413740	DNA methyltransferase 1 and 3B activate BAG-1 expression via recruitment of CTCFL/BORIS and modulation of promoter histone methylation.

Q08CI8	S238A_DANRE	Solute carrier family 25 member 38-A	19412178	Mutations in mitochondrial carrier family gene SLC25A38 cause nonsyndromic autosomal recessive congenital sideroblastic anemia.

Q9JIF3	GTR8_MOUSE	Solute carrier family 2, facilitated glucose transporter member 8	10860996	GLUT8 is a glucose transporter responsible for insulin-stimulated glucose uptake in the blastocyst.

P50995	ANX11_HUMAN	Annexin A11	12601007	Calcium- and cell cycle-dependent association of annexin 11 with the nuclear envelope.

P40325	HUA1_YEAST	Proline-rich protein HUA1	11914276	Subcellular localization of the yeast proteome.

Q674R7	ATG9B_HUMAN	Autophagy-related protein 9B	15755735	Endothelial nitric-oxide synthase antisense (NOS3AS) gene encodes an autophagy-related protein (APG9-like2) highly expressed in trophoblast.

Q15051	IQCB1_HUMAN	IQ calmodulin-binding motif-containing protein 1	15723066	Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior- Loken syndrome and interacts with RPGR and calmodulin.

P38881	NVJ1_YEAST	Nucleus-vacuole junction protein 1	10888680	Nucleus-vacuole junctions in Saccharomyces cerevisiae are formed through the direct interaction of Vac8p with Nvj1p.

Q9LEZ3	BIM1_ARATH	Transcription factor BIM1	15680330	A new class of transcription factors mediates brassinosteroid- regulated gene expression in Arabidopsis.

P0A6B7	ISCS_ECOLI	Cysteine desulfurase	10781607	The iscS gene in Escherichia coli is required for the biosynthesis of 4-thiouridine, thiamin, and NAD.

Q9Y2T1	AXN2_HUMAN	Axin-2	11017067	Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling.

Q9UKV8	AGO2_HUMAN	Protein argonaute-2	17524464	An mRNA m7G cap binding-like motif within human Ago2 represses translation.

P40084	RTR1_YEAST	RNA polymerase II subunit B1 CTD phosphatase RTR1	14562095	Global analysis of protein localization in budding yeast.

P38825	TOM71_YEAST	Protein TOM71	8663394	Tom71, a novel homologue of the mitochondrial preprotein receptor Tom70.

P51826	AFF3_HUMAN	AF4/FMR2 family member 3	8555498	LAF-4 encodes a lymphoid nuclear protein with transactivation potential that is homologous to AF-4, the gene fused to MLL in t(4;11) leukemias.

Q9LVI4	TIF6B_ARATH	Protein TIFY 6B	20360743	NINJA connects the co-repressor TOPLESS to jasmonate signalling.

Q9VRK8	PLBL_DROME	Putative phospholipase B-like lamina ancestor	16077094	Regulation of cellular plasticity in Drosophila imaginal disc cells by the Polycomb group, trithorax group and lama genes.

Q12242	RUP1_YEAST	UBA domain-containing protein RUP1	14562095	Global analysis of protein localization in budding yeast.

P0ABZ1	FLIG_ECOLI	Flagellar motor switch protein FliG	8631704	A mutational analysis of the interaction between FliG and FliM, two components of the flagellar motor of Escherichia coli.

P12883	MYH7_HUMAN	Myosin-7	2249844	The complete sequence of the human beta-myosin heavy chain gene and a comparative analysis of its product.

Q9VA70	NCASE_DROME	Neutral ceramidase	15356190	Ceramidase regulates synaptic vesicle exocytosis and trafficking.

O14170	POP2_SCHPO	WD repeat-containing protein pop2	9990507	Two F-box/WD-repeat proteins Pop1 and Pop2 form hetero- and homo- complexes together with cullin-1 in fission yeast SCF (Skip-cullin-1- F-box) ubiquitin ligase.

P31943	HNRH1_HUMAN	Heterogeneous nuclear ribonucleoprotein H	7499401	Heterogeneous nuclear ribonucleoproteins H, H', and F are members of a ubiquitously expressed subfamily of related but distinct proteins encoded by genes mapping to different chromosomes.

P35433	PUR1_RAT	Amidophosphoribosyltransferase	8463258	Molecular cloning of rat amidophosphoribosyltransferase.

Q09920	FIO1_SCHPO	Iron transport multicopper oxidase fio1	8995275	An oxidase-permease-based iron transport system in Schizosaccharomyces pombe and its expression in Saccharomyces cerevisiae.

P43688	NKX26_MOUSE	Homeobox protein Nkx-2.6	9545560	Expression of NK-2 class homeobox gene Nkx2-6 in foregut endoderm and heart.

P49723	RIR4_YEAST	Ribonucleoside-diphosphate reductase small chain 2	12732713	Subcellular localization of yeast ribonucleotide reductase regulated by the DNA replication and damage checkpoint pathways.

Q23976	KU70_DROME	ATP-dependent DNA helicase 2 subunit 1	8157678	Yolk protein factor 1 is a Drosophila homolog of Ku, the DNA-binding subunit of a DNA-dependent protein kinase from humans.

Q9US06	PAF1_SCHPO	RNA polymerase II-associated protein 1 homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P98203	ARVC_MOUSE	Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog	11058098	The armadillo repeat region targets ARVCF to cadherin-based cellular junctions.

P41886	BAT41_CAEEL	BTB and MATH domain-containing protein 41	13679922	BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3.

Q7JRJ1	EAF_DROME	Ell-associated factor Eaf	18562276	Regulation of the transcriptional activity of poised RNA polymerase II by the elongation factor ELL.

Q16206	ENOX2_HUMAN	Ecto-NOX disulfide-thiol exchanger 2	9932650	The sulfonylurea-inhibited NADH oxidase activity of HeLa cell plasma membranes has properties of a protein disulfide-thiol oxidoreductase with protein disulfide-thiol interchange activity.

Q9H2C0	GAN_HUMAN	Gigaxonin	16303566	Gigaxonin interacts with tubulin folding cofactor B and controls its degradation through the ubiquitin-proteasome pathway.

P06704	CDC31_YEAST	Cell division control protein 31	12486115	Mps3p is a novel component of the yeast spindle pole body that interacts with the yeast centrin homologue Cdc31p.

Q9UUK0	PDXH_SCHPO	Pyridoxamine 5'-phosphate oxidase C1952.08c homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P84103	SRSF3_HUMAN	Serine/arginine-rich splicing factor 3	15169763	Distinct sequence motifs within the 68-kDa subunit of cleavage factor Im mediate RNA binding, protein-protein interactions, and subcellular localization.

O35827	APBB3_RAT	Amyloid beta A4 precursor protein-binding family B member 3	9461550	Fe65L2: a new member of the Fe65 protein family interacting with the intracellular domain of the Alzheimer's beta-amyloid precursor protein.

P16649	TUP1_YEAST	General transcriptional corepressor TUP1	11069890	Ssn6-Tup1 interacts with class I histone deacetylases required for repression.

Q9GZU1	MCLN1_HUMAN	Mucolipin-1	11013137	Cloning of the gene encoding a novel integral membrane protein, mucolipidin, and identification of the two major founder mutations causing mucolipidosis type IV.

O18209	PMY13_CAEEL	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase wee-1.3	12397109	Dominant mutations in the Caenorhabditis elegans Myt1 ortholog wee- 1.3 reveal a novel domain that controls M-phase entry during spermatogenesis.

Q13619	CUL4A_HUMAN	Cullin-4A	12609982	TIP120A associates with cullins and modulates ubiquitin ligase activity.

P20290	BTF3_HUMAN	Transcription factor BTF3	1386332	Genomic structure of the putative BTF3 transcription factor.

P63047	ST4A1_RAT	Sulfotransferase 4A1	10698717	Molecular cloning and expression of novel sulphotransferase-like cDNAs from human and rat brain.

P30776	RAD21_SCHPO	Cohesin subunit rad21	1480481	Cloning and characterization of rad21 an essential gene of Schizosaccharomyces pombe involved in DNA double-strand-break repair.

Q9UTA2	FMP46_SCHPO	Putative redox protein fmp46, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P34241	URB1_YEAST	Nucleolar pre-ribosomal-associated protein 1	15208443	Npa1p is an essential trans-acting factor required for an early step in the assembly of 60S ribosomal subunits in Saccharomyces cerevisiae.

P23471	PTPRZ_HUMAN	Receptor-type tyrosine-protein phosphatase zeta	1323835	A human transmembrane protein-tyrosine-phosphatase, PTP zeta, is expressed in brain and has an N-terminal receptor domain homologous to carbonic anhydrases.

P42748	UBC4_ARATH	Ubiquitin-conjugating enzyme E2 4	8790283	Members of two gene families encoding ubiquitin-conjugating enzymes, AtUBC1-3 and AtUBC4-6, from Arabidopsis thaliana are differentially expressed.

Q9NZJ0	DTL_HUMAN	Denticleless protein homolog	17041588	CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation.

Q9SA72	Y1357_ARATH	Probable receptor-like protein kinase At1g30570	17317660	Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.

Q9DDY9	PAB2A_XENLA	Polyadenylate-binding protein 2-A	11677061	Poly(A) binding protein II in Xenopus laevis is expressed in developing brain and pancreas.

Q7M712	TR110_MOUSE	Taste receptor type 2 member 110	11854532	Expression of bitter taste receptors of the T2R family in the gastrointestinal tract and enteroendocrine STC-1 cells.

Q06417	YL426_YEAST	Uncharacterized oxidoreductase YLR426W	16121259	Genome-wide requirements for resistance to functionally distinct DNA- damaging agents.

P46680	AIP1_YEAST	Actin-interacting protein 1	10366597	Aip1p interacts with cofilin to disassemble actin filaments.

P46951	YPP1_YEAST	Cargo-transport protein YPP1	16702403	Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes.

P14384	CBPM_HUMAN	Carboxypeptidase M	2753907	Molecular cloning and sequencing of the cDNA for human membrane-bound carboxypeptidase M. Comparison with carboxypeptidases A, B, H, and N.

Q6QNK2	GP133_HUMAN	Probable G-protein coupled receptor 133	15203201	The human and mouse repertoire of the adhesion family of G-protein- coupled receptors.

Q9UT46	MOC3_SCHPO	Transcriptional regulatory protein moc3	16273369	Moc3, a novel Zn finger type protein involved in sexual development, ascus formation, and stress response of Schizosaccharomyces pombe.

P38261	EXO84_YEAST	Exocyst complex component EXO84	10438536	Exo84p is an exocyst protein essential for secretion.

Q08479	KAD1_ORYSJ	Adenylate kinase A	1302636	Molecular characterization of cDNA encoding for adenylate kinase of rice (Oryza sativa L.).

Q9W0T1	NU301_DROME	Nucleosome-remodeling factor subunit NURF301	16264191	The Drosophila nucleosome remodeling factor NURF is required for Ecdysteroid signaling and metamorphosis.

Q9VXG8	ATR_DROME	Serine/threonine-protein kinase ATR	11676920	mei-41 and bub1 block mitosis at two distinct steps in response to incomplete DNA replication in Drosophila embryos.

Q9ASS6	CP20B_ARATH	Peptidyl-prolyl cis-trans isomerase CYP20-2, chloroplastic	11719511	Proteome map of the chloroplast lumen of Arabidopsis thaliana.

Q9ERE9	JIP2_MOUSE	C-Jun-amino-terminal kinase-interacting protein 2	10827199	The reelin receptor ApoER2 recruits JNK-interacting proteins-1 and -2.

Q9VQS6	DRM_DROME	Protein drumstick	14597202	The odd-skipped family of zinc finger genes promotes Drosophila leg segmentation.

Q07651	FMP45_YEAST	SUR7 family protein FMP45	11784867	The Sur7p family defines novel cortical domains in Saccharomyces cerevisiae, affects sphingolipid metabolism, and is involved in sporulation.

P53267	DAM1_YEAST	DASH complex subunit DAM1	15640796	The yeast DASH complex forms closed rings on microtubules.

Q95YF3	CGH1_CAEEL	ATP-dependent RNA helicase cgh-1	11546739	cgh-1, a conserved predicted RNA helicase required for gametogenesis and protection from physiological germline apoptosis in C. elegans.

P53315	SOL4_YEAST	6-phosphogluconolactonase 4	14562095	Global analysis of protein localization in budding yeast.

P36597	THI3_SCHPO	Pyrimidine precursor biosynthesis enzyme thi3	2358444	nmt1 of fission yeast. A highly transcribed gene completely repressed by thiamine.

Q9P2R6	RERE_HUMAN	Arginine-glutamic acid dipeptide repeats protein	10814707	Protein binding of a DRPLA family through arginine-glutamic acid dipeptide repeats is enhanced by extended polyglutamine.

Q8VY52	PPD2_ARATH	PsbP domain-containing protein 2, chloroplastic	18431481	Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.

P49711	CTCF_HUMAN	Transcriptional repressor CTCF	16595548	Targeting of CTCF to the nucleolus inhibits nucleolar transcription through a poly(ADP-ribosyl)ation-dependent mechanism.

O14618	CCS_HUMAN	Copper chaperone for superoxide dismutase	9295278	The copper chaperone for superoxide dismutase.

P87227	MIS6_SCHPO	Inner centromere protein mis6	10864871	Requirement of Mis6 centromere connector for localizing a CENP-A-like protein in fission yeast.

Q94524	DYLT_DROME	Dynein light chain Tctex-type	15090621	The Drosophila tctex-1 light chain is dispensable for essential cytoplasmic dynein functions but is required during spermatid differentiation.

Q9R0T8	IKKE_MOUSE	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	10421793	IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IkappaB kinases.

Q60670	SIK1_MOUSE	Serine/threonine-protein kinase SIK1	16817901	Silencing the constitutive active transcription factor CREB by the LKB1-SIK signaling cascade.

P0C092	CSEN4_MOUSE	Calsenilin isoform 4	11161465	Mouse DREAM/calsenilin/KChIP3: gene structure, coding potential and expression.

P38264	PHO88_YEAST	Inorganic phosphate transport protein PHO88	16823961	Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Q9NQ94	A1CF_HUMAN	APOBEC1 complementation factor	10781591	Purification and molecular cloning of a novel essential component of the apolipoprotein B mRNA editing enzyme-complex.

Q8LBV4	Y1814_ARATH	Uncharacterized methyltransferase At1g78140, chloroplastic	16414959	Tocopherol cyclase (VTE1) localization and vitamin E accumulation in chloroplast plastoglobule lipoprotein particles.

Q96EV8	DTBP1_HUMAN	Dysbindin	19349376	TRIM32 is an E3 ubiquitin ligase for dysbindin.

P17157	PHO85_YEAST	Cyclin-dependent protein kinase PHO85	8539622	Regulation of PHO4 nuclear localization by the PHO80-PHO85 cyclin-CDK complex.

P54657	CAD1_DICDI	Calcium-dependent cell adhesion molecule 1	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q92526	TCPW_HUMAN	T-complex protein 1 subunit zeta-2	8812458	Isolation of three testis-specific genes (TSA303, TSA806, TSA903) by a differential mRNA display method.

P34278	KNL1_CAEEL	Kinetochore null protein 1	16273096	Differential role of CENP-A in the segregation of holocentric C. elegans chromosomes during meiosis and mitosis.

Q9V853	SMUF1_DROME	E3 ubiquitin-protein ligase Smurf1	11703946	The DSmurf ubiquitin-protein ligase restricts BMP signaling spatially and temporally during Drosophila embryogenesis.

Q01926	MRS2_YEAST	Magnesium transporter MRS2, mitochondrial	12628916	Mrs2p is an essential component of the major electrophoretic Mg2+ influx system in mitochondria.

Q13153	PAK1_HUMAN	Serine/threonine-protein kinase PAK 1	12624090	The C-terminal kinase domain of the p34cdc2-related PITSLRE protein kinase (p110C) associates with p21-activated kinase 1 and inhibits its activity during anoikis.

P29717	EXG_CANAL	Glucan 1,3-beta-glucosidase	9013549	Identification of Glu-330 as the catalytic nucleophile of Candida albicans exo-beta-(1,3)-glucanase.

P41250	SYG_HUMAN	Glycyl-tRNA synthetase	17544401	Crystal structure of human wildtype and S581L-mutant glycyl-tRNA synthetase, an enzyme underlying distal spinal muscular atrophy.

Q9Z2E1	MBD2_MOUSE	Methyl-CpG-binding domain protein 2	9774669	Identification and characterization of a family of mammalian methyl- CpG binding proteins.

Q8LGE3	ARP6_ARATH	Actin-related protein 6	17142478	SEF, a new protein required for flowering repression in Arabidopsis, interacts with PIE1 and ARP6.

Q12285	MDY2_YEAST	Ubiquitin-like protein MDY2	16390866	Mdy2, a ubiquitin-like (UBL)-domain protein, is required for efficient mating in Saccharomyces cerevisiae.

Q9NPF8	ADAP2_HUMAN	Arf-GAP with dual PH domain-containing protein 2	14690521	Identification of gene structure and subcellular localization of human centaurin alpha 2, and p42IP4, a family of two highly homologous, Ins 1,3,4,5-P4-/PtdIns 3,4,5-P3-binding, adapter proteins.

P14866	HNRPL_HUMAN	Heterogeneous nuclear ribonucleoprotein L	17289661	Molecular composition of IMP1 ribonucleoprotein granules.

Q62910	SYNJ1_RAT	Synaptojanin-1	9238017	The SH3p4/Sh3p8/SH3p13 protein family: binding partners for synaptojanin and dynamin via a Grb2-like Src homology 3 domain.

Q9P0G3	KLK14_HUMAN	Kallikrein-14	17110383	Expression and functional characterization of the cancer-related serine protease, human tissue kallikrein 14.

P77432	LSRK_ECOLI	Autoinducer 2 kinase lsrK	17557827	Quorum sensing in Escherichia coli is signaled by AI-2/LsrR: effects on small RNA and biofilm architecture.

P12391	ACHB3_RAT	Neuronal acetylcholine receptor subunit beta-3	2703489	Beta 3: a new member of nicotinic acetylcholine receptor gene family is expressed in brain.

O95347	SMC2_HUMAN	Structural maintenance of chromosomes protein 2	10958694	A human condensin complex containing hCAP-C-hCAP-E and CNAP1, a homolog of Xenopus XCAP-D2, colocalizes with phosphorylated histone H3 during the early stage of mitotic chromosome condensation.

Q04049	POLH_YEAST	DNA polymerase eta	10601233	Fidelity and processivity of Saccharomyces cerevisiae DNA polymerase eta.

O42860	BUB3_SCHPO	Mitotic checkpoint protein bub3	11909965	Fission yeast Mad3p is required for Mad2p to inhibit the anaphase- promoting complex and localizes to kinetochores in a Bub1p-, Bub3p-, and Mph1p-dependent manner.

P40212	RL13B_YEAST	60S ribosomal protein L13-B	9559554	The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Q8L9W3	ATL23_ARATH	E3 ubiquitin-protein ligase ATL23	15644464	Functional analysis of the RING-type ubiquitin ligase family of Arabidopsis.

Q3E7D0	NAT12_ARATH	Nucleobase-ascorbate transporter 12	14506206	Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.

O14417	MAD2_SCHPO	Mitotic spindle checkpoint component mad2	9461438	Fission yeast Slp1: an effector of the Mad2-dependent spindle checkpoint.

Q13507	TRPC3_HUMAN	Short transient receptor potential channel 3	15757897	MxA, a member of the dynamin superfamily, interacts with the ankyrin- like repeat domain of TRPC.

P0AFC0	NUDB_ECOLI	Dihydroneopterin triphosphate pyrophosphatase	17698004	Structure and function of the E. coli dihydroneopterin triphosphate pyrophosphatase: a Nudix enzyme involved in folate biosynthesis.

Q9NVM4	ANM7_HUMAN	Protein arginine N-methyltransferase 7	17709427	Two distinct arginine methyltransferases are required for biogenesis of Sm-class ribonucleoproteins.

O16850	FOXO_CAEEL	Forkhead box protein O	17894411	The MAP kinase JNK-1 of Caenorhabditis elegans: location, activation, and influences over temperature-dependent insulin-like signaling, stress responses, and fitness.

Q9SSA5	CYP38_ARATH	Peptidyl-prolyl cis-trans isomerase CYP38, chloroplastic	11719511	Proteome map of the chloroplast lumen of Arabidopsis thaliana.

P07834	CDC4_YEAST	Cell division control protein 4	11080155	Nuclear-specific degradation of Far1 is controlled by the localization of the F-box protein Cdc4.

D0ZVG2	SSPH1_SALT1	E3 ubiquitin-protein ligase sspH1	10861017	A conserved amino acid sequence directing intracellular type III secretion by Salmonella typhimurium.

Q12923	PTN13_HUMAN	Tyrosine-protein phosphatase non-receptor type 13	14516276	Interaction of the protein tyrosine phosphatase PTPL1 with the PtdIns(3,4)P2-binding adaptor protein TAPP1.

P38054	CUSA_ECOLI	Cation efflux system protein cusA	11283292	The product of the ybdE gene of the Escherichia coli chromosome is involved in detoxification of silver ions.

Q9LSX8	ASK10_ARATH	SKP1-like protein 10	19682297	An F-box gene, CPR30, functions as a negative regulator of the defense response in Arabidopsis.

Q4X1A4	MTLD_ASPFU	Mannitol-1-phosphate 5-dehydrogenase	18983992	Polyol-specific long-chain dehydrogenases/reductases of mannitol metabolism in Aspergillus fumigatus: biochemical characterization and pH studies of mannitol 2-dehydrogenase and mannitol-1-phosphate 5- dehydrogenase.

Q2UHL4	PGLR1_ASPOR	Endopolygalacturonase I	9720204	Utilization of the TEF1-alpha gene (TEF1) promoter for expression of polygalacturonase genes, pgaA and pgaB, in Aspergillus oryzae.

P21888	SYC_ECOLI	Cysteinyl-tRNA synthetase	12032090	Structural origins of amino acid selection without editing by cysteinyl-tRNA synthetase.

Q9UST9	YGO5_SCHPO	UPF0486 protein C336.05c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P12107	COBA1_HUMAN	Collagen alpha-1(XI) chain	10486316	Splicing mutations of 54-bp exons in the COL11A1 gene cause Marshall syndrome, but other mutations cause overlapping Marshall/Stickler phenotypes.

Q04437	KU80_YEAST	ATP-dependent DNA helicase II subunit 2	12975323	Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends.

P50135	HNMT_HUMAN	Histamine N-methyltransferase	7943261	Structure and function of human histamine N-methyltransferase: critical enzyme in histamine metabolism in airway.

Q12962	TAF10_HUMAN	Transcription initiation factor TFIID subunit 10	10373431	Identification of TATA-binding protein-free TAFII-containing complex subunits suggests a role in nucleosome acetylation and signal transduction.

Q12320	GLO4_YEAST	Hydroxyacylglutathione hydrolase, mitochondrial	9261170	Identification and phenotypic analysis of two glyoxalase II encoding genes from Saccharomyces cerevisiae, GLO2 and GLO4, and intracellular localization of the corresponding proteins.

O74858	SYKM_SCHPO	Lysyl-tRNA synthetase, mitochondrial	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12063	UPPS_YEAST	Probable undecaprenyl pyrophosphate synthase	10515935	Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiae.

Q9WVH3	FOXO4_MOUSE	Forkhead box protein O4	11353388	Identification and characterization of members of the FKHR (FOX O) subclass of winged-helix transcription factors in the mouse.

P98082	DAB2_HUMAN	Disabled homolog 2	9620555	DOC-2, a candidate tumor suppressor gene in human epithelial ovarian cancer.

Q9YHV3	NOGG3_DANRE	Noggin-3	10491267	Three different noggin genes antagonize the activity of bone morphogenetic proteins in the zebrafish embryo.

Q9Y692	GMEB1_HUMAN	Glucocorticoid modulatory element-binding protein 1	10386584	Cloning and characterization of hGMEB1, a novel glucocorticoid modulatory element binding protein.

P01165	7B2_PIG	Neuroendocrine protein 7B2	6514132	Tissue distribution and molecular forms of a novel pituitary protein in the rat.

Q02721	RE102_YEAST	Meiotic recombination protein REC102	12897161	Support for a meiotic recombination initiation complex: interactions among Rec102p, Rec104p, and Spo11p.

Q9NPB6	PAR6A_HUMAN	Partitioning defective 6 homolog alpha	11260256	Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42 to atypical protein kinase C.

O42634	DMC1_SCHPO	Meiotic recombination protein dmc1	10908327	Dmc1 of Schizosaccharomyces pombe plays a role in meiotic recombination.

P27801	PEP3_YEAST	Vacuolar membrane protein PEP3	1944264	Isolation and characterization of PEP3, a gene required for vacuolar biogenesis in Saccharomyces cerevisiae.

Q5AX28	AGALD_EMENI	Alpha-galactosidase D	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

P86146	MASOD_ORADR	Eumenine mastoparan-OD	18695936	Novel mastoparan and protonectin analogs isolated from a solitary wasp, Orancistrocerus drewseni drewseni.

Q6Q788	APOA5_HUMAN	Apolipoprotein A-V	17997385	Normal binding of lipoprotein lipase, chylomicrons, and apo-AV to GPIHBP1 containing a G56R amino acid substitution.

Q99N27	SNX1_RAT	Sorting nexin-1	11110793	Hrs interacts with sorting nexin 1 and regulates degradation of epidermal growth factor receptor.

P50106	RPA14_YEAST	DNA-directed RNA polymerase I subunit RPA14	7768955	The association of three subunits with yeast RNA polymerase is stabilized by A14.

Q92817	EVPL_HUMAN	Envoplakin	8707850	Envoplakin, a novel precursor of the cornified envelope that has homology to desmoplakin.

Q9Y7Y5	RT109_SCHPO	Histone acetyltransferase rtt109	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q5BK26	PLPL7_RAT	Patatin-like phospholipase domain-containing protein 7	12893290	Rat NTE-related esterase is a membrane-associated protein, hydrolyzes phenyl valerate, and interacts with diisopropylfluorophosphate through a serine catalytic machinery.

Q12905	ILF2_HUMAN	Interleukin enhancer-binding factor 2	9442054	DNA-dependent protein kinase interacts with antigen receptor response element binding proteins NF90 and NF45.

O43613	OX1R_HUMAN	Orexin receptor type 1	9491897	Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior.

Q9NTI5	PDS5B_HUMAN	Sister chromatid cohesion protein PDS5 homolog B	10215036	Early gene expression during androgen-induced inhibition of proliferation of prostate cancer cells: a new suppressor candidate on chromosome 13, in the BRCA2-Rb1 locus.

Q925Q9	SH3K1_RAT	SH3 domain-containing kinase-binding protein 1	15147912	Identification and characterization of a novel Rho GTPase activating protein implicated in receptor-mediated endocytosis.

Q9BX66	SRBS1_HUMAN	Sorbin and SH3 domain-containing protein 1	12504111	The c-Cbl-associated protein and c-Cbl are two new partners of the SH2-containing inositol polyphosphate 5-phosphatase SHIP2.

P37296	STV1_YEAST	V-type proton ATPase subunit a, Golgi isoform	7514599	STV1 gene encodes functional homologue of 95-kDa yeast vacuolar H(+)- ATPase subunit Vph1p.

Q1PE39	MRS26_ARATH	Magnesium transporter MRS2-6, mitochondrial	19966073	A root-expressed magnesium transporter of the MRS2/MGT gene family in Arabidopsis thaliana allows for growth in low-Mg2+ environments.

Q3ZB98	BCAS1_RAT	Breast carcinoma-amplified sequence 1 homolog	12427555	Cloning and characterization of a novel synaptosome-enriched mRNA that encodes 31 kDa protein.

P53905	LSM7_YEAST	U6 snRNA-associated Sm-like protein LSm7	10369684	Sm and Sm-like proteins assemble in two related complexes of deep evolutionary origin.

P24588	AKAP5_HUMAN	A-kinase anchor protein 5	1512224	Localization of the cAMP-dependent protein kinase to the postsynaptic densities by A-kinase anchoring proteins. Characterization of AKAP 79.

Q9QZ86	NOP58_RAT	Nucleolar protein 58	10679015	Conserved composition of mammalian box H/ACA and box C/D small nucleolar ribonucleoprotein particles and their interaction with the common factor Nopp140.

O15540	FABP7_HUMAN	Fatty acid-binding protein, brain	9375786	Isolation and expression of a cDNA for human brain fatty acid-binding protein (B-FABP).

P53675	CLH2_HUMAN	Clathrin heavy chain 2	8733128	Isolation of a new clathrin heavy chain gene with muscle-specific expression from the region commonly deleted in velo-cardio-facial syndrome.

P40581	GPX3_YEAST	Peroxiredoxin HYR1	10480913	Genetic analysis of glutathione peroxidase in oxidative stress response of Saccharomyces cerevisiae.

A1Z6W3	PRIC1_DROME	Protein prickle	12941693	Prickle and Strabismus form a functional complex to generate a correct axis during planar cell polarity signaling.

Q8K3W3	CASC3_MOUSE	Protein CASC3	12843282	Barentsz, a new component of the Staufen-containing ribonucleoprotein particles in mammalian cells, interacts with Staufen in an RNA- dependent manner.

Q14767	LTBP2_HUMAN	Latent-transforming growth factor beta-binding protein 2	7798248	Identification and characterization of LTBP-2, a novel latent transforming growth factor-beta-binding protein.

Q969W0	SSPTA_HUMAN	Small subunit of serine palmitoyltransferase A	19416851	Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities.

P49336	CDK8_HUMAN	Cell division protein kinase 8	15546612	Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover.

Q9UHE5	NAT8_HUMAN	Probable N-acetyltransferase 8	9852678	Isolation and mapping of a novel human kidney- and liver-specific gene homologous to the bacterial acetyltransferases.

Q9UBC3	DNM3B_HUMAN	DNA (cytosine-5)-methyltransferase 3B	18567530	DNA methyltransferase 3B acts as a co-repressor of the human polycomb protein hPc2 to repress fibroblast growth factor receptor 3 transcription.

Q5FVJ0	RUFY3_RAT	Protein RUFY3	17439943	Singar1, a novel RUN domain-containing protein, suppresses formation of surplus axons for neuronal polarity.

P36211	RK122_ARATH	50S ribosomal protein L12-2, chloroplastic	8125949	Multicopy GTPase center protein L12 of Arabidopsis chloroplast ribosome is encoded by a clustered nuclear gene family with the expressed members closely linked to tRNA(Pro) genes.

P51955	NEK2_HUMAN	Serine/threonine-protein kinase Nek2	17621308	Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis.

P35631	AP1_ARATH	Floral homeotic protein APETALA 1	11206550	Complexes of MADS-box proteins are sufficient to convert leaves into floral organs.

Q12791	KCMA1_HUMAN	Calcium-activated potassium channel subunit alpha-1	7877450	Cloning and expression of a human large-conductance calcium-activated potassium channel.

Q84MA8	AZG2_ARATH	Adenine/guanine permease AZG2	19121308	AtAzg1 and AtAzg2 comprise a novel family of purine transporters in Arabidopsis.

P14646	PDE4B_RAT	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	12441002	Molecular cloning and subcellular distribution of the novel PDE4B4 cAMP-specific phosphodiesterase isoform.

Q04433	FIT1_YEAST	Facilitator of iron transport 1	10383953	Amino acid residues in the omega-minus region participate in cellular localization of yeast glycosylphosphatidylinositol-attached proteins.

Q9NRA1	PDGFC_HUMAN	Platelet-derived growth factor C	10858496	A novel gene derived from developing spinal cords, SCDGF, is a unique member of the PDGF/VEGF family.

P26433	SL9A3_RAT	Sodium/hydrogen exchanger 3	16293618	Shank2 associates with and regulates Na+/H+ exchanger 3.

Q8BMA3	CNKR3_MOUSE	Connector enhancer of kinase suppressor of ras 3	19567370	Cnksr3 is a direct mineralocorticoid receptor target gene and plays a key role in the regulation of the epithelial sodium channel.

P03406	NEF_HV1BR	Protein Nef	8794306	Human immunodeficiency virus type 1 Nef binds directly to LCK and mitogen-activated protein kinase, inhibiting kinase activity.

Q9EQL9	SHRPN_RAT	Sharpin	11178875	Sharpin, a novel postsynaptic density protein that directly interacts with the shank family of proteins.

Q12461	PTPA2_YEAST	Serine/threonine-protein phosphatase 2A activator 2	12952889	A novel and essential mechanism determining specificity and activity of protein phosphatase 2A (PP2A) in vivo.

Q9Y6B2	EID1_HUMAN	EP300-interacting inhibitor of differentiation 1	11073990	A novel Rb- and p300-binding protein inhibits transactivation by MyoD.

Q9V429	THIO2_DROME	Thioredoxin-2	11877442	Thioredoxin-2 but not thioredoxin-1 is a substrate of thioredoxin peroxidase-1 from Drosophila melanogaster: isolation and characterization of a second thioredoxin in D.melanogaster and evidence for distinct biological functions of Trx-1 and Trx-2.

Q9YGL1	SPD1B_XENLA	Speedy protein 1-B	11730327	RINGO efficiently triggers meiosis resumption in mouse oocytes and induces cell cycle arrest in embryos.

P84253	MOSB_AZOVD	Molybdenum storage protein subunit beta	15651045	A new type of metalloprotein: the Mo storage protein from Azotobacter vinelandii contains a polynuclear molybdenum-oxide cluster.

Q61112	CAB45_MOUSE	45 kDa calcium-binding protein	8609160	Cab45, a novel (Ca2+)-binding protein localized to the Golgi lumen.

O75874	IDHC_HUMAN	Isocitrate dehydrogenase [NADP] cytoplasmic	19935646	Cancer-associated IDH1 mutations produce 2-hydroxyglutarate.

P38361	PHO89_YEAST	Phosphate permease PHO89	9671031	Identification, cloning and characterization of a derepressible Na+- coupled phosphate transporter in Saccharomyces cerevisiae.

O00217	NDUS8_HUMAN	NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

Q54J47	PDX1_DICDI	Probable pyridoxine biosynthesis protein pdx1	16926386	Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake.

Q969L4	LSM10_HUMAN	U7 snRNA-associated Sm-like protein LSm10	16914750	ZFP100, a component of the active U7 snRNP limiting for histone pre- mRNA processing, is required for entry into S phase.

P39990	SNU13_YEAST	13 kDa ribonucleoprotein-associated protein	12068309	A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis.

Q9WVJ4	SYJ2B_RAT	Synaptojanin-2-binding protein	10357812	Recruitment of an alternatively spliced form of synaptojanin 2 to mitochondria by the interaction with the PDZ domain of a mitochondrial outer membrane protein.

O76329	ACTNB_DICDI	Interaptin	9700162	Interaptin, an actin-binding protein of the alpha-actinin superfamily in Dictyostelium discoideum, is developmentally and cAMP-regulated and associates with intracellular membrane compartments.

Q9VN93	CPR1_DROME	Putative cysteine proteinase CG12163	12593804	A SAGE approach to discovery of genes involved in autophagic cell death.

Q13501	SQSTM_HUMAN	Sequestosome-1	11244088	The atypical protein kinase C-interacting protein p62 is a scaffold for NF-kappaB activation by nerve growth factor.

P53720	DUS2_YEAST	tRNA-dihydrouridine synthase 2	12003496	A conserved family of Saccharomyces cerevisiae synthases effects dihydrouridine modification of tRNA.

P83706	HLOB_HALAU	Halocidin subunit B	12067731	Halocidin: a new antimicrobial peptide from hemocytes of the solitary tunicate, Halocynthia aurantium.

O95396	MOCS3_HUMAN	Adenylyltransferase and sulfurtransferase MOCS3	17459099	Site-directed mutagenesis of the active site loop of the rhodanese- like domain of the human molybdopterin synthase sulfurase MOCS3. Major differences in substrate specificity between eukaryotic and bacterial homologs.

P45970	LIN5_CAEEL	Spindle apparatus protein lin-5	12730122	A complex of LIN-5 and GPR proteins regulates G protein signaling and spindle function in C elegans.

O54698	S29A1_RAT	Equilibrative nucleoside transporter 1	9353301	Molecular cloning and functional characterization of nitrobenzylthioinosine (NBMPR)-sensitive (es) and NBMPR-insensitive (ei) equilibrative nucleoside transporter proteins (rENT1 and rENT2) from rat tissues.

Q06672	TSR2_YEAST	Pre-rRNA-processing protein TSR2	12837249	A panoramic view of yeast noncoding RNA processing.

P41743	KPCI_HUMAN	Protein kinase C iota type	11260256	Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42 to atypical protein kinase C.

P35576	G6PC_MOUSE	Glucose-6-phosphatase	8407995	Isolation of the gene for murine glucose-6-phosphatase, the enzyme deficient in glycogen storage disease type 1A.

P35691	TCTP_YEAST	Translationally-controlled tumor protein homolog	16806052	MMI1 (YKL056c, TMA19), the yeast orthologue of the translationally controlled tumor protein (TCTP) has apoptotic functions and interacts with both microtubules and mitochondria.

P78955	HUS1_SCHPO	Checkpoint protein hus1	9180692	Molecular analysis of hus1+, a fission yeast gene required for S-M and DNA damage checkpoints.

Q12192	RFM1_YEAST	Repression factor of MSEs protein 1	12612074	Rfm1, a novel tethering factor required to recruit the hst1 histone deacetylase for repression of middle sporulation genes.

Q7T2V3	M3K10_XENLA	Mitogen-activated protein kinase kinase kinase 10	12753919	PAK interacts with NCK and MLK2 to regulate the activation of jun N- terminal kinase.

P28300	LYOX_HUMAN	Protein-lysine 6-oxidase	1357535	The complete derived amino acid sequence of human lysyl oxidase and assignment of the gene to chromosome 5 (extensive sequence homology with the murine ras recision gene).

Q09XV5	CHD8_MOUSE	Chromodomain-helicase-DNA-binding protein 8	19151705	CHD8 suppresses p53-mediated apoptosis through histone H1 recruitment during early embryogenesis.

O13820	ERG5_SCHPO	Cytochrome P450 61	17276356	Dap1/PGRMC1 binds and regulates cytochrome P450 enzymes.

P15884	ITF2_HUMAN	Transcription factor 4	2105528	Two distinct transcription factors that bind the immunoglobulin enhancer microE5/kappa 2 motif.

Q67Y93	KRP1_ARATH	Cyclin-dependent kinase inhibitor 1	16376885	Arabidopsis KRPs have distinct inhibitory activity toward cyclin D2- associated kinases, including plant-specific B-type cyclin-dependent kinase.

P29972	AQP1_HUMAN	Aquaporin-1	7521540	Mutations in aquaporin-1 in phenotypically normal humans without functional CHIP water channels.

O70310	NMT1_MOUSE	Glycylpeptide N-tetradecanoyltransferase 1	9506952	A second mammalian N-myristoyltransferase.

P47142	VPS25_YEAST	Vacuolar protein-sorting-associated protein 25	15469844	ESCRT-II, an endosome-associated complex required for protein sorting: crystal structure and interactions with ESCRT-III and membranes.

Q9UKT9	IKZF3_HUMAN	Zinc finger protein Aiolos	10552935	Human aiolos, an ikaros-related zinc finger DNA binding protein: cDNA cloning, tissue expression pattern, and chromosomal mapping.

P46889	FTSK_ECOLI	DNA translocase ftsK	17057717	The FtsK gamma domain directs oriented DNA translocation by interacting with KOPS.

P38257	MMS4_YEAST	Crossover junction endonuclease MMS4	11641278	Functional overlap between Sgs1-Top3 and the Mms4-Mus81 endonuclease.

O75603	GCM2_HUMAN	Chorion-specific transcription factor GCMb	15728199	GCMB mutation in familial isolated hypoparathyroidism with residual secretion of parathyroid hormone.

P01011	AACT_HUMAN	Alpha-1-antichymotrypsin	9880565	Molecular studies define the primary structure of alpha1- antichymotrypsin (ACT) protease inhibitor in Alzheimer's disease brains. Comparison of act in hippocampus and liver.

O08721	UNC5A_RAT	Netrin receptor UNC5A	9126742	Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors.

Q06217	SMD2_YEAST	Small nuclear ribonucleoprotein Sm D2	9012791	Identification of the proteins of the yeast U1 small nuclear ribonucleoprotein complex by mass spectrometry.

P36601	RAD51_SCHPO	DNA repair protein rhp51	15899844	Fission yeast rad51 and dmc1, two efficient DNA recombinases forming helical nucleoprotein filaments.

Q42588	SAT1_ARATH	Serine acetyltransferase 1, chloroplastic	7851429	Subcellular distribution of serine acetyltransferase from Pisum sativum and characterization of an Arabidopsis thaliana putative cytosolic isoform.

P78385	KRT83_HUMAN	Keratin, type II cuticular Hb3	9084137	Sequences and differential expression of three novel human type-II hair keratins.

P06401	PRGR_HUMAN	Progesterone receptor	3551956	Complete amino acid sequence of the human progesterone receptor deduced from cloned cDNA.

Q12824	SNF5_HUMAN	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1	7801128	Binding and stimulation of HIV-1 integrase by a human homolog of yeast transcription factor SNF5.

O42924	EAF7_SCHPO	Probable chromatin modification-related protein eaf7	10759889	Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

P39717	GPB2_YEAST	Guanine nucleotide-binding protein subunit beta 2	12150916	The Galpha protein Gpa2 controls yeast differentiation by interacting with kelch repeat proteins that mimic Gbeta subunits.

Q06523	YP148_YEAST	Uncharacterized protein YPR148C	14562095	Global analysis of protein localization in budding yeast.

P55826	PPOC_ARATH	Protoporphyrinogen oxidase, chloroplastic	8982084	Molecular cloning and characterization of a cDNA that encodes protoporphyrinogen oxidase of Arabidopsis thaliana.

P36132	KAE1_YEAST	Putative glycoprotein endopeptidase KAE1	14562095	Global analysis of protein localization in budding yeast.

Q8IWU4	ZNT8_HUMAN	Zinc transporter 8	15331542	Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules.

Q9XSC1	SFRP5_BOVIN	Secreted frizzled-related protein 5	10072424	Cloning and characterization of a secreted frizzled-related protein that is expressed by the retinal pigment epithelium.

Q8K4P2	NPB_RAT	Neuropeptide B	12118011	Identification of a neuropeptide modified with bromine as an endogenous ligand for GPR7.

P83741	WNK1_MOUSE	Serine/threonine-protein kinase WNK1	12671053	WNK kinases regulate thiazide-sensitive Na-Cl cotransport.

P67809	YBOX1_HUMAN	Nuclease-sensitive element-binding protein 1	3174636	Characterization of the cDNA encoding a protein binding to the major histocompatibility complex class II Y box.

P10114	RAP2A_HUMAN	Ras-related protein Rap-2a	1900290	The product of the rap2 gene, member of the ras superfamily. Biochemical characterization and site-directed mutagenesis.

Q9VFX1	WNT8_DROME	Wnt inhibitor of Dorsal protein	12717451	Wnt proteins are lipid-modified and can act as stem cell growth factors.

Q96QA5	GSDMA_HUMAN	Gasdermin-A	17471240	GASDERMIN, suppressed frequently in gastric cancer, is a target of LMO1 in TGF-beta-dependent apoptotic signalling.

P34766	PAL1_CAEEL	Homeobox protein pal-1	8861906	Spatial and temporal controls target pal-1 blastomere-specification activity to a single blastomere lineage in C. elegans embryos.

Q9JKU1	TR119_RAT	Taste receptor type 2 member 119	10761934	A novel family of mammalian taste receptors.

Q21955	MED15_CAEEL	Mediator of RNA polymerase II transcription subunit 15	16799563	An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis.

Q9NRD8	DUOX2_HUMAN	Dual oxidase 2	15972824	Dual oxidase-2 has an intrinsic Ca2+-dependent H2O2-generating activity.

P57740	NU107_HUMAN	Nuclear pore complex protein Nup107	11564755	An evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cells.

Q9N4X8	GSTPA_CAEEL	Glutathione S-transferase P 10	16300482	Lifespan extension in hypomorphic daf-2 mutants of Caenorhabditis elegans is partially mediated by glutathione transferase CeGSTP2-2.

Q9UHM6	OPN4_HUMAN	Melanopsin	10632589	A novel human opsin in the inner retina.

P81928	140U_DROME	RPII140-upstream gene protein	1905256	Analysis of the promoter region of the housekeeping gene DmRP140 by sequence comparison of Drosophila melanogaster and Drosophila virilis.

P35346	SSR5_HUMAN	Somatostatin receptor type 5	7908405	Molecular cloning, functional characterization, and chromosomal localization of a human somatostatin receptor (somatostatin receptor type 5) with preferential affinity for somatostatin-28.

Q99222	AFI1_YEAST	ARF3-interacting protein 1	18397879	Afi1p functions as an Arf3p polarization-specific docking factor for development of polarity.

Q09908	PHF2_SCHPO	SWM histone demethylase complex subunit phf2	17434129	S. pombe LSD1 homologs regulate heterochromatin propagation and euchromatic gene transcription.

P53886	APC1_YEAST	Anaphase-promoting complex subunit 1	12609981	Mnd2 and Swm1 are core subunits of the Saccharomyces cerevisiae anaphase-promoting complex.

Q3TC93	H1BP3_MOUSE	HCLS1-binding protein 3	10590261	Isolation and characterization of a novel HS1 SH3 domain binding protein, HS1BP3.

P42881	GPT_SCHPO	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	7893167	Asparagine-linked glycosylation in Schizosaccharomyces pombe: functional conservation of the first step in oligosaccharide-lipid assembly.

P40989	FKS2_YEAST	1,3-beta-glucan synthase component GSC2	7565718	Differential expression and function of two homologous subunits of yeast 1,3-beta-D-glucan synthase.

Q96CS2	HAUS1_HUMAN	HAUS augmin-like complex subunit 1	19427217	HAUS, the 8-subunit human augmin complex, regulates centrosome and spindle integrity.

O43708	MAAI_HUMAN	Maleylacetoacetate isomerase	9417084	Characterization of a fungal maleylacetoacetate isomerase gene and identification of its human homologue.

Q9QZR0	RNF25_MOUSE	E3 ubiquitin-protein ligase RNF25	18757723	EGF receptor-independent action of TGF-alpha protects Naked2 from AO7-mediated ubiquitylation and proteasomal degradation.

P20084	RM33_YEAST	54S ribosomal protein L33, mitochondrial	2060626	Extended N-terminal sequencing of proteins of the large ribosomal subunit from yeast mitochondria.

P11633	NHP6B_YEAST	Non-histone chromosomal protein 6B	7721780	DNA looping by Saccharomyces cerevisiae high mobility group proteins NHP6A/B. Consequences for nucleoprotein complex assembly and chromatin condensation.

P21675	TAF1_HUMAN	Transcription initiation factor TFIID subunit 1	8625415	TAFII250 is a bipartite protein kinase that phosphorylates the base transcription factor RAP74.

Q9JJ28	FLII_MOUSE	Protein flightless-1 homolog	11971982	Fliih, a gelsolin-related cytoskeletal regulator essential for early mammalian embryonic development.

Q08722	CD47_HUMAN	Leukocyte surface antigen CD47	7998989	Isolation and characterization of CD47 glycoprotein: a multispanning membrane protein which is the same as integrin-associated protein (IAP) and the ovarian tumour marker OA3.

Q9UER7	DAXX_HUMAN	Death domain-associated protein 6	11948183	Essential role of the 58-kDa microspherule protein in the modulation of Daxx-dependent transcriptional repression as revealed by nucleolar sequestration.

O09012	PEX5_MOUSE	Peroxisomal targeting signal 1 receptor	9288097	A mouse model for Zellweger syndrome.

Q9UHD0	IL19_HUMAN	Interleukin-19	11196675	Cloning, expression and initial characterization of interleukin-19 (IL-19), a novel homolog of human interleukin-10 (IL-10).

Q08281	YO128_YEAST	Uncharacterized WD repeat-containing protein YOL138C	14562095	Global analysis of protein localization in budding yeast.

O77059	CRY1_DROME	Cryptochrome-1	11448767	Light-dependent interaction between Drosophila CRY and the clock protein PER mediated by the carboxy terminus of CRY.

P48025	KSYK_MOUSE	Tyrosine-protein kinase SYK	16456001	Scaffolding adapter Grb2-associated binder 2 requires Syk to transmit signals from FcepsilonRI.

P32906	MNS1_YEAST	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase	1714453	Glycoprotein biosynthesis in Saccharomyces cerevisiae. Isolation and characterization of the gene encoding a specific processing alpha- mannosidase.

P61981	1433G_HUMAN	14-3-3 protein gamma	19172738	Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein.

Q15185	TEBP_HUMAN	Prostaglandin E synthase 3	10922363	Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in immediate prostaglandin E2 biosynthesis.

Q9Y5E3	PCDB6_HUMAN	Protocadherin beta-6	11322959	The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number.

Q13423	NNTM_HUMAN	NAD(P) transhydrogenase, mitochondrial	10673423	The high-resolution structure of the NADP(H)-binding component (dIII) of proton-translocating transhydrogenase from human heart mitochondria.

Q9V9U4	DOHH_DROME	Deoxyhypusine hydroxylase	19546244	The Drosophila deoxyhypusine hydroxylase homologue nero and its target eIF5A are required for cell growth and the regulation of autophagy.

P15919	RAG1_MOUSE	V(D)J recombination-activating protein 1	19448632	RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci.

P15390	SCN4A_RAT	Sodium channel protein type 4 subunit alpha	9613589	Expression of skeletal muscle-type voltage-gated Na+ channel in rat and human prostate cancer cell lines.

O08523	TECTA_MOUSE	Alpha-tectorin	9079715	The mouse tectorins. Modular matrix proteins of the inner ear homologous to components of the sperm-egg adhesion system.

P38788	SSZ1_YEAST	Ribosome-associated complex subunit SSZ1	11274393	RAC, a stable ribosome-associated complex in yeast formed by the DnaK-DnaJ homologs Ssz1p and zuotin.

P51636	CAV2_HUMAN	Caveolin-2	8552590	Identification, sequence, and expression of caveolin-2 defines a caveolin gene family.

O08901	BUB1_MOUSE	Mitotic checkpoint serine/threonine-protein kinase BUB1	17938250	Bub1 mediates cell death in response to chromosome missegregation and acts to suppress spontaneous tumorigenesis.

P47069	MPS3_YEAST	Spindle pole body assembly component MPS3	12493774	Nep98p is a component of the yeast spindle pole body and essential for nuclear division and fusion.

P48002	KNAT5_ARATH	Homeobox protein knotted-1-like 5	11701881	The Arabidopsis BELL1 and KNOX TALE homeodomain proteins interact through a domain conserved between plants and animals.

Q16827	PTPRO_HUMAN	Receptor-type tyrosine-protein phosphatase O	19167335	Large-scale structural analysis of the classical human protein tyrosine phosphatome.

P32790	SLA1_YEAST	Actin cytoskeleton-regulatory complex protein SLA1	17286805	Nucleocytoplasmic trafficking is required for functioning of the adaptor protein Sla1p in endocytosis.

Q9BXS0	COPA1_HUMAN	Collagen alpha-1(XXV) chain	15615705	CLAC binds to amyloid beta peptides through the positively charged amino acid cluster within the collagenous domain 1 and inhibits formation of amyloid fibrils.

Q9UJT1	TBD_HUMAN	Tubulin delta chain	10620804	Delta-tubulin and epsilon-tubulin: two new human centrosomal tubulins reveal new aspects of centrosome structure and function.

O54864	SUV91_MOUSE	Histone-lysine N-methyltransferase SUV39H1	10949293	Regulation of chromatin structure by site-specific histone H3 methyltransferases.

Q9SRZ0	CUL2_ARATH	Cullin-2	12795696	Protein interaction analysis of SCF ubiquitin E3 ligase subunits from Arabidopsis.

Q99MV7	RNF17_MOUSE	RING finger protein 17	16093322	RNF17, a component of the mammalian germ cell nuage, is essential for spermiogenesis.

P46671	FAR3_YEAST	Factor arrest protein 3	12588993	Far3 and five interacting proteins prevent premature recovery from pheromone arrest in the budding yeast Saccharomyces cerevisiae.

Q9UF11	PKHB1_HUMAN	Pleckstrin homology domain-containing family B member 1	10585447	PHR1 encodes an abundant, pleckstrin homology domain-containing integral membrane protein in the photoreceptor outer segments.

P04000	OPSR_HUMAN	Red-sensitive opsin	2937147	Molecular genetics of human color vision: the genes encoding blue, green, and red pigments.

P40544	YKE4_YEAST	Zinc transporter YKE4	16760462	YKE4 (YIL023C) encodes a bidirectional zinc transporter in the endoplasmic reticulum of Saccharomyces cerevisiae.

P47138	DPH4_YEAST	Diphthamide biosynthesis protein 4	14562095	Global analysis of protein localization in budding yeast.

P36162	DAD2_YEAST	DASH complex subunit DAD2	11799062	The mitotic spindle is required for loading of the DASH complex onto the kinetochore.

Q9SU67	RAC8_ARATH	Rac-like GTP-binding protein ARAC8	12417701	Plasma membrane-associated ROP10 small GTPase is a specific negative regulator of abscisic acid responses in Arabidopsis.

Q15046	SYK_HUMAN	Lysyl-tRNA synthetase	10952987	The human lysyl-tRNA synthetase gene encodes both the cytoplasmic and mitochondrial enzymes by means of an unusual alternative splicing of the primary transcript.

Q9UBT2	SAE2_HUMAN	SUMO-activating enzyme subunit 2	10187858	Identification of the enzyme required for activation of the small ubiquitin-like protein SUMO-1.

P49354	FNTA_HUMAN	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	8276393	cDNA cloning of the two subunits of human CAAX farnesyltransferase and chromosomal mapping of FNTA and FNTB loci and related sequences.

P43291	SRK2A_ARATH	Serine/threonine-protein kinase SRK2A	15292193	Identification of nine sucrose nonfermenting 1-related protein kinases 2 activated by hyperosmotic and saline stresses in Arabidopsis thaliana.

P29410	KAD2_RAT	Adenylate kinase 2, mitochondrial	8468325	Tissue-specific and developmentally regulated expression of the genes encoding adenylate kinase isozymes.

P38736	GOS1_YEAST	Protein transport protein GOS1	9755865	Gos1p, a Saccharomyces cerevisiae SNARE protein involved in Golgi transport.

O48963	PHOT1_ARATH	Phototropin-1	12383086	Phototropin LOV domains exhibit distinct roles in regulating photoreceptor function.

Q5QJU3	ACER2_HUMAN	Alkaline ceramidase 2	18945876	Alkaline ceramidase 2 regulates beta1 integrin maturation and cell adhesion.

Q99MR0	ACL6B_MOUSE	Actin-like protein 6B	12437990	Brain-specific expression of the nuclear actin-related protein ArpNalpha and its involvement in mammalian SWI/SNF chromatin remodeling complex.

Q86KF9	SPHKA_DICDI	Sphingosine kinase A	15643073	Sphingosine kinase regulates the sensitivity of Dictyostelium discoideum cells to the anticancer drug cisplatin.

O96133	YB145_PLAF7	Uncharacterized protein PFB0145c	17653272	Rapid identification of malaria vaccine candidates based on alpha- helical coiled coil protein motif.

Q14008	CKAP5_HUMAN	Cytoskeleton-associated protein 5	11903063	Interaction of the transforming acidic coiled-coil 1 (TACC1) protein with ch-TOG and GAS41/NuBI1 suggests multiple TACC1-containing protein complexes in human cells.

Q01341	ADCY6_MOUSE	Adenylate cyclase type 6	1379717	Cloning and expression of a Ca(2+)-inhibitable adenylyl cyclase from NCB-20 cells.

P27037	AVR2A_HUMAN	Activin receptor type-2A	1314589	Molecular cloning and binding properties of the human type II activin receptor.

Q12359	ATO3_YEAST	Ammonia transport outward protein 3	12966084	ATO3 encoding a putative outward ammonium transporter is an RTG- independent retrograde responsive gene regulated by GCN4 and the Ssy1- Ptr3-Ssy5 amino acid sensor system.

Q08229	NBA1_YEAST	Protein NBA1	18086883	Phosphorylation by casein kinase 2 regulates Nap1 localization and function.

P29704	FDFT_YEAST	Squalene synthase	2068081	Molecular cloning and characterization of the yeast gene for squalene synthetase.

P49446	PTPRE_MOUSE	Receptor-type tyrosine-protein phosphatase epsilon	18006633	Cytosolic protein tyrosine phosphatase-epsilon is a negative regulator of insulin signaling in skeletal muscle.

Q16254	E2F4_HUMAN	Transcription factor E2F4	16360038	Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release.

Q60900	ELAV3_MOUSE	ELAV-like protein 3	10734193	NMR studies on functional structures of the AU-rich element-binding domains of Hu antigen C.

Q7RTX0	TS1R3_HUMAN	Taste receptor type 1 member 3	11917125	Human receptors for sweet and umami taste.

O73689	ZIC1_XENLA	Zinc finger protein ZIC 1	9739105	Xenopus Zic family and its role in neural and neural crest development.

Q05029	BCH1_YEAST	Protein BCH1	16498409	Arf1p, Chs5p and the ChAPs are required for export of specialized cargo from the Golgi.

O74515	ASF1_SCHPO	Histone chaperone cia1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P51875	GNAO_CAEEL	Guanine nucleotide-binding protein G(o) subunit alpha	12730122	A complex of LIN-5 and GPR proteins regulates G protein signaling and spindle function in C elegans.

P35191	MDJ1_YEAST	DnaJ homolog 1, mitochondrial	8168133	Mdj1p, a novel chaperone of the DnaJ family, is involved in mitochondrial biogenesis and protein folding.

Q08230	SDHF2_YEAST	Succinate dehydrogenase assembly factor 2, mitochondrial	14576278	The proteome of Saccharomyces cerevisiae mitochondria.

Q6PML9	ZNT9_HUMAN	Zinc transporter 9	10409434	The novel human HUEL (C4orf1) gene maps to chromosome 4p12-p13 and encodes a nuclear protein containing the nuclear receptor interaction motif.

Q9BYX4	IFIH1_HUMAN	Interferon-induced helicase C domain-containing protein 1	19531363	Structural basis of double-stranded RNA recognition by the RIG-I like receptor MDA5.

P42596	RLMG_ECOLI	Ribosomal RNA large subunit methyltransferase G	17010380	Identification of Escherichia coli m2G methyltransferases: II. The ygjO gene encodes a methyltransferase specific for G1835 of the 23 S rRNA.

B1AUH1	PTPRU_MOUSE	Receptor-type tyrosine-protein phosphatase U	9054423	A novel protein-tyrosine phosphatase related to the homotypically adhering kappa and mu receptors.

P68209	SUCA1_ARATH	Succinyl-CoA ligase [GDP-forming] subunit alpha-1, mitochondrial	11743114	Proteomic approach to identify novel mitochondrial proteins in Arabidopsis.

O70458	OSMR_MOUSE	Oncostatin-M-specific receptor subunit beta	9920829	Reconstitution of the functional mouse oncostatin M (OSM) receptor: molecular cloning of the OSM receptor beta subunit.

O14545	TRAD1_HUMAN	TRAF-type zinc finger domain-containing protein 1	16221674	FLN29, a novel interferon- and LPS-inducible gene acting as a negative regulator of toll-like receptor signaling.

P23381	SYWC_HUMAN	Tryptophanyl-tRNA synthetase, cytoplasmic	8496617	Gamma interferon potently induces tryptophanyl-tRNA synthetase expression in human keratinocytes.

Q06160	SPH1_YEAST	Protein SPH1	11923536	Role of a ubiquitin-like modification in polarized morphogenesis.

O13758	YF28_SCHPO	Uncharacterized protein C17A2.08c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9YGC3	CXR4A_XENLA	C-X-C chemokine receptor type 4-A	11069075	Characterization of a Xenopus laevis CXC chemokine receptor 4: implications for hematopoietic cell development in the vertebrate embryo.

P22830	HEMH_HUMAN	Ferrochelatase, mitochondrial	8973195	Site-directed mutagenesis and spectroscopic characterization of human ferrochelatase: identification of residues coordinating the [2Fe-2S] cluster.

Q1A3R1	CT54_CONLT	T-conotoxin Lt5.4	17961831	Isolation and characterization of a T-superfamily conotoxin from Conus litteratus with targeting tetrodotoxin-sensitive sodium channels.

P21524	RIR1_YEAST	Ribonucleoside-diphosphate reductase large chain 1	16537479	Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation.

Q99593	TBX5_HUMAN	T-box transcription factor TBX5	8988165	Mutations in human TBX5 cause limb and cardiac malformation in Holt- Oram syndrome.

O42652	AATC_SCHPO	Aspartate aminotransferase, cytoplasmic	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P40850	MKT1_YEAST	Protein MKT1	7532890	Sequence of MKT1, needed for propagation of M2 satellite dsRNA of the L-A virus of Saccharomyces cerevisiae.

O14328	KSP1_SCHPO	Serine/threonine-protein kinase ksp1	15821139	Systematic deletion analysis of fission yeast protein kinases.

Q05466	HAT4_ARATH	Homeobox-leucine zipper protein HAT4	8106086	The Arabidopsis Athb-2 and -4 genes are strongly induced by far-red- rich light.

Q9UKT5	FBX4_HUMAN	F-box only protein 4	20159592	Structural basis of selective ubiquitination of TRF1 by SCFFbx4.

B1Q006	MBOA4_DANRE	Ghrelin O-acyltransferase	18443287	Ghrelin octanoylation mediated by an orphan lipid transferase.

P53742	NOG2_YEAST	Nucleolar GTP-binding protein 2	11707418	Nog2p, a putative GTPase associated with pre-60S subunits and required for late 60S maturation steps.

P14618	KPYM_HUMAN	Pyruvate kinase isozymes M1/M2	17308100	Nuclear translocation of the tumor marker pyruvate kinase M2 induces programmed cell death.

O14468	YO304_YEAST	Uncharacterized protein YOR304C-A	14562095	Global analysis of protein localization in budding yeast.

O15498	YKT6_HUMAN	Synaptobrevin homolog YKT6	9211930	Ykt6p, a prenylated SNARE essential for endoplasmic reticulum-Golgi transport.

Q9V6X7	OFUT1_DROME	GDP-fucose protein O-fucosyltransferase 1	12917292	Neurotic, a novel maternal neurogenic gene, encodes an O- fucosyltransferase that is essential for Notch-Delta interactions.

P51808	DYLT3_HUMAN	Dynein light chain Tctex-type 3	17289665	The DYNLT3 light chain directly links cytoplasmic dynein to a spindle checkpoint protein, Bub3.

Q96RL1	UIMC1_HUMAN	BRCA1-A complex subunit RAP80	17525341	RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites.

O00170	AIP_HUMAN	AH receptor-interacting protein	9111057	Ligand-dependent interaction of the aryl hydrocarbon receptor with a novel immunophilin homolog in vivo.

Q8WXG9	GPR98_HUMAN	G-protein coupled receptor 98	16434480	The DFNB31 gene product whirlin connects to the Usher protein network in the cochlea and retina by direct association with USH2A and VLGR1.

Q66K89	E4F1_HUMAN	Transcription factor E4F1	10869426	pRB binds to and modulates the transrepressing activity of the E1A- regulated transcription factor p120E4F.

Q9UT96	YL43_SCHPO	Uncharacterized protein C323.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q7KNF2	PABP2_DROME	Polyadenylate-binding protein 2	10481015	The Drosophila poly(A)-binding protein II is ubiquitous throughout Drosophila development and has the same function in mRNA polyadenylation as its bovine homolog in vitro.

Q02772	PT191_YEAST	Mitochondrial protein PET191	8381337	Sequence and chromosomal localization of two PET genes required for cytochrome c oxidase assembly in Saccharomyces cerevisiae.

Q95RA8	MOB1_DROME	Mps one binder kinase activator-like 1	15766530	Control of cell proliferation and apoptosis by mob as tumor suppressor, mats.

P39928	SLN1_YEAST	Osmosensing histidine protein kinase SLN1	8808622	Yeast HOG1 MAP kinase cascade is regulated by a multistep phosphorelay mechanism in the SLN1-YPD1-SSK1 two-component osmosensor.

P19438	TNR1A_HUMAN	Tumor necrosis factor receptor superfamily member 1A	1698610	Soluble forms of tumor necrosis factor receptors (TNF-Rs). The cDNA for the type I TNF-R, cloned using amino acid sequence data of its soluble form, encodes both the cell surface and a soluble form of the receptor.

P50222	MEOX2_HUMAN	Homeobox protein MOX-2	7713505	Molecular cloning and localization of the human GAX gene to 7p21.

Q06623	HDA3_YEAST	HDA1 complex subunit 3	11287668	HDA2 and HDA3 are related proteins that interact with and are essential for the activity of the yeast histone deacetylase HDA1.

O54960	CAPON_RAT	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein	11086993	Dexras1: a G protein specifically coupled to neuronal nitric oxide synthase via CAPON.

Q8WP90	PBGP9_SOLIN	Pheromone-binding protein Gp-9	11711637	Identification of a major gene regulating complex social behavior.

Q9M0X9	4CLL7_ARATH	4-coumarate--CoA ligase-like 7	15677481	A new type of peroxisomal acyl-coenzyme A synthetase from Arabidopsis thaliana has the catalytic capacity to activate biosynthetic precursors of jasmonic acid.

P31641	SC6A6_HUMAN	Sodium- and chloride-dependent taurine transporter	8010975	Functional characterization and chromosomal localization of a cloned taurine transporter from human placenta.

P0AC81	LGUL_ECOLI	Lactoylglutathione lyase	9628737	Overproduction and characterization of a dimeric non-zinc glyoxalase I from Escherichia coli: evidence for optimal activation by nickel ions.

Q9V3D4	IDGF2_DROME	Chitinase-like protein Idgf2	9847235	A new family of growth factors produced by the fat body and active on Drosophila imaginal disc cells.

P25008	CCNC_DROME	Cyclin-C	1833067	An evolutionarily conserved cyclin homolog from Drosophila rescues yeast deficient in G1 cyclins.

P35688	LRG1_YEAST	Rho-GTPase-activating protein LRG1	11447600	Yeast Lrg1p acts as a specialized RhoGAP regulating 1,3-beta-glucan synthesis.

Q96AX9	MIB2_HUMAN	E3 ubiquitin-protein ligase MIB2	12761501	Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.

Q96G21	IMP4_HUMAN	U3 small nucleolar ribonucleoprotein protein IMP4	12655004	The human Imp3 and Imp4 proteins form a ternary complex with hMpp10, which only interacts with the U3 snoRNA in 60-80S ribonucleoprotein complexes.

Q9P7K6	SDO1L_SCHPO	SDO1-like protein C21C3.19	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q62233	SIX3_MOUSE	Homeobox protein SIX3	8814301	Identification and expression of Six family genes in mouse retina.

Q8RWU4	ATML1_ARATH	Homeobox-leucine zipper protein MERISTEM L1	11439135	Identification of a cis-regulatory element for L1 layer-specific gene expression, which is targeted by an L1-specific homeodomain protein.

P23204	PPARA_MOUSE	Peroxisome proliferator-activated receptor alpha	16950137	Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway.

Q969S8	HDA10_HUMAN	Histone deacetylase 10	11861901	Identification of HDAC10, a novel class II human histone deacetylase containing a leucine-rich domain.

P30532	ACHA5_HUMAN	Neuronal acetylcholine receptor subunit alpha-5	1542648	Neuronal-type alpha-bungarotoxin receptors and the alpha 5-nicotinic receptor subunit gene are expressed in neuronal and nonneuronal human cell lines.

P40380	RUM1_SCHPO	Cyclin-dependent kinase inhibitor rum1	9303310	p25rum1 promotes proteolysis of the mitotic B-cyclin p56cdc13 during G1 of the fission yeast cell cycle.

P28040	DPOA_SCHPO	DNA polymerase alpha catalytic subunit	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q109R6	CUTA1_ORYSJ	Protein CutA 1, chloroplastic	18154307	Thermodynamic basis for the stabilities of three CutA1s from Pyrococcus horikoshii,Thermus thermophilus, and Oryza sativa, with unusually high denaturation temperatures.

Q9UBQ5	EIF3K_HUMAN	Eukaryotic translation initiation factor 3 subunit K	18599441	Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3.

P0AC41	DHSA_ECOLI	Succinate dehydrogenase flavoprotein subunit	6383359	Nucleotide sequence encoding the flavoprotein and hydrophobic subunits of the succinate dehydrogenase of Escherichia coli.

Q9UHE5	NAT8_HUMAN	Probable N-acetyltransferase 8	11397015	Overexpression of camello, a member of a novel protein family, reduces blastomere adhesion and inhibits gastrulation in Xenopus laevis.

Q13564	ULA1_HUMAN	NEDD8-activating enzyme E1 regulatory subunit	10722740	The amyloid precursor protein-binding protein APP-BP1 drives the cell cycle through the S-M checkpoint and causes apoptosis in neurons.

Q8VY06	PREP2_ARATH	Presequence protease 2, chloroplastic/mitochondrial	15827031	Catalysis, subcellular localization, expression and evolution of the targeting peptides degrading protease, AtPreP2.

P01130	LDLR_HUMAN	Low-density lipoprotein receptor	17142622	Genetic causes of familial hypercholesterolaemia in patients in the UK: relation to plasma lipid levels and coronary heart disease risk.

Q92540	SMG7_HUMAN	Protein SMG7	14636577	Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7.

Q9EPR2	PG12A_MOUSE	Group XIIA secretory phospholipase A2	11278438	A novel group of phospholipase A2s preferentially expressed in type 2 helper T cells.

Q13049	TRI32_HUMAN	E3 ubiquitin-protein ligase TRIM32	19349376	TRIM32 is an E3 ubiquitin ligase for dysbindin.

O13935	YF6H_SCHPO	Putative tRNA (cytosine-5-)-methyltransferase C23C4.17	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9P7W7	YGQ3_SCHPO	Uncharacterized ARM-like repeat-containing protein C1703.03c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

P30041	PRDX6_HUMAN	Peroxiredoxin-6	10893423	1-Cys peroxiredoxin, a bifunctional enzyme with glutathione peroxidase and phospholipase A2 activities.

Q20735	SMS2_CAEEL	Putative phosphatidylcholine:ceramide cholinephosphotransferase 2	14685263	Identification of a family of animal sphingomyelin synthases.

P07858	CATB_HUMAN	Cathepsin B	18718938	Epileptic and developmental disorders of the speech cortex: ligand/receptor interaction of wild-type and mutant SRPX2 with the plasminogen activator receptor uPAR.

Q99312	ISN1_YEAST	IMP-specific 5'-nucleotidase 1	12735798	The yeast ISN1 (YOR155c) gene encodes a new type of IMP-specific 5'- nucleotidase.

P48634	BAT2_HUMAN	Large proline-rich protein BAT2	14667819	Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region.

Q3T040	RT07_BOVIN	28S ribosomal protein S7, mitochondrial	11402041	Proteomic analysis of the mammalian mitochondrial ribosome. Identification of protein components in the 28S small subunit.

Q02630	NU116_YEAST	Nucleoporin NUP116/NSP116	11104765	The GLFG regions of Nup116p and Nup100p serve as binding sites for both Kap95p and Mex67p at the nuclear pore complex.

Q61955	KLK8_MOUSE	Kallikrein-8	9556608	Characterization of recombinant and brain neuropsin, a plasticity- related serine protease.

P0ACN4	ALLR_ECOLI	HTH-type transcriptional repressor AllR	12460564	Regulation of the Escherichia coli allantoin regulon: coordinated function of the repressor AllR and the activator AllS.

Q9NSC7	SIA7A_HUMAN	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1	10536037	Cloning and expression of a human gene encoding an N- acetylgalactosamine-alpha2,6-sialyltransferase (ST6GalNac I); a candidate for synthesis of cancer-associated sialyl-Tnantigens.

Q16585	SGCB_HUMAN	Beta-sarcoglycan	7581448	Beta-sarcoglycan: characterization and role in limb-girdle muscular dystrophy linked to 4q12.

O70247	SC5A6_RAT	Sodium-dependent multivitamin transporter	9516450	Cloning and functional expression of a cDNA encoding a mammalian sodium-dependent vitamin transporter mediating the uptake of pantothenate, biotin, and lipoate.

Q8R1B8	RORB_MOUSE	Nuclear receptor ROR-beta	16574740	Activation of the blue opsin gene in cone photoreceptor development by retinoid-related orphan receptor beta.

P15919	RAG1_MOUSE	V(D)J recombination-activating protein 1	9228952	Crystal structure of the RAG1 dimerization domain reveals multiple zinc-binding motifs including a novel zinc binuclear cluster.

Q9Y287	ITM2B_HUMAN	Integral membrane protein 2B	10391242	A stop-codon mutation in the BRI gene associated with familial British dementia.

Q99611	SPS2_HUMAN	Selenide, water dikinase 2	8986768	Identification of a novel selD homolog from eukaryotes, bacteria, and archaea: is there an autoregulatory mechanism in selenocysteine metabolism?

Q9H900	ZWILC_HUMAN	Protein zwilch homolog	15824131	ZW10 links mitotic checkpoint signaling to the structural kinetochore.

O74741	DIOXL_SCHPO	4,5-DOPA dioxygenase extradiol-like protein	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q62908	CSRP2_RAT	Cysteine and glycine-rich protein 2	8626582	Molecular cloning and characterization of SmLIM, a developmentally regulated LIM protein preferentially expressed in aortic smooth muscle cells.

P67870	CSK2B_HUMAN	Casein kinase II subunit beta	1856204	Structure of the gene encoding human casein kinase II subunit beta.

Q9DBG9	TX1B3_MOUSE	Tax1-binding protein 3	12874278	The PDZ protein tax-interacting protein-1 inhibits beta-catenin transcriptional activity and growth of colorectal cancer cells.

Q96P65	QRFPR_HUMAN	Pyroglutamylated RFamide peptide receptor	12960173	A new peptidic ligand and its receptor regulating adrenal function in rats.

P24931	RUBY_DESVH	Rubrerythrin	8646540	The structure of Desulfovibrio vulgaris rubrerythrin reveals a unique combination of rubredoxin-like FeS4 and ferritin-like diiron domains.

Q9UT72	RFP2_SCHPO	E3 ubiquitin-protein ligase complex slx8-rfp subunit rfp2	17502373	Fission yeast Rnf4 homologs are required for DNA repair.

Q19289	IFB1_CAEEL	Intermediate filament protein ifb-1	14975728	Intermediate filaments are required for C. elegans epidermal elongation.

Q8VBV4	FBXW7_MOUSE	F-box/WD repeat-containing protein 7	11425854	Functional interaction between SEL-10, an F-box protein, and the nuclear form of activated Notch1 receptor.

O18373	SPS1_DROME	Selenide, water dikinase	9398525	SelD homolog from Drosophila lacking selenide-dependent monoselenophosphate synthetase activity.

P31825	TRMN6_ECOLI	tRNA (adenine-N(6)-)-methyltransferase	19383770	The yfiC gene of E. coli encodes an adenine-N6 methyltransferase that specifically modifies A37 of tRNA1Val(cmo5UAC).

O94813	SLIT2_HUMAN	Slit homolog 2 protein	10975526	Squeezing axons out of the gray matter: a role for slit and semaphorin proteins from midline and ventral spinal cord.

Q58WW2	DCAF6_HUMAN	DDB1- and CUL4-associated factor 6	16949367	A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1.

Q8LAD7	IDA_ARATH	Protein IDA	12972671	Inflorescence deficient in abscission controls floral organ abscission in Arabidopsis and identifies a novel family of putative ligands in plants.

P01701	LV103_HUMAN	Ig lambda chain V-I region NEW	4177823	The complete amino acid sequence of Bence Jones protein New (lambda- type). Subgroups in the variable part of immunoglobulin L-chains of the lambda-type.

P52944	PDLI1_RAT	PDZ and LIM domain protein 1	8522188	Cloning of a rat cDNA encoding a novel LIM domain protein with high homology to rat RIL.

P53197	CDH1_YEAST	APC/C activator protein CDH1	9831566	Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex.

Q9UKT5	FBX4_HUMAN	F-box only protein 4	20181953	Structural basis of dimerization-dependent ubiquitination by the SCF(Fbx4) ubiquitin ligase.

P31107	DMS2_PHYBI	Adenoregulin	8306981	Isolation and structure of novel defensive peptides from frog skin.

O15205	UBD_HUMAN	Ubiquitin D	10200259	A MHC-encoded ubiquitin-like protein (FAT10) binds noncovalently to the spindle assembly checkpoint protein MAD2.

Q86U42	PABP2_HUMAN	Polyadenylate-binding protein 2	15169763	Distinct sequence motifs within the 68-kDa subunit of cleavage factor Im mediate RNA binding, protein-protein interactions, and subcellular localization.

Q0KI50	DMDD_DROME	Dystrophin, isoform D	17543506	Drosophila Dystrophin is required for integrity of the musculature.

P25786	PSA1_HUMAN	Proteasome subunit alpha type-1	17292860	Conserved signal peptide of Notch3 inhibits interaction with proteasome.

Q61245	COBA1_MOUSE	Collagen alpha-1(XI) chain	7859283	A fibrillar collagen gene, Col11a1, is essential for skeletal morphogenesis.

P80315	TCPD_MOUSE	T-complex protein 1 subunit delta	7953530	Identification of six Tcp-1-related genes encoding divergent subunits of the TCP-1-containing chaperonin.

Q7FGZ2	RH1_ARATH	DEAD-box ATP-dependent RNA helicase 1	9358062	Structure, organization and putative function of the genes identified within a 23.9 kb fragment from Arabidopsis thaliana chromosome IV sequenced in the framework of the ESSA programme.

O14561	ACPM_HUMAN	Acyl carrier protein, mitochondrial	12611891	The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

P08034	CXB1_HUMAN	Gap junction beta-1 protein	8266101	Connexin mutations in X-linked Charcot-Marie-Tooth disease.

P35348	ADA1A_HUMAN	Alpha-1A adrenergic receptor	9490024	Molecular cloning, genomic characterization and expression of novel human alpha1A-adrenoceptor isoforms.

O88794	PNPO_RAT	Pyridoxine-5'-phosphate oxidase	9601034	Absence of pyridoxine-5'-phosphate oxidase (PNPO) activity in neoplastic cells: isolation, characterization, and expression of PNPO cDNA.

O74368	MMM1_SCHPO	Maintenance of mitochondrial morphology protein 1	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

O74823	YBJC_SCHPO	Zinc finger CCCH domain-containing protein C337.12	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9QYG8	UCK2_RAT	Uridine-cytidine kinase 2	10581173	Up-regulated uridine kinase gene identified by RLCS in the ventral horn after crush injury to rat sciatic nerves.

O00519	FAAH1_HUMAN	Fatty-acid amide hydrolase 1	9122178	Molecular characterization of human and mouse fatty acid amide hydrolases.

P31371	FGF9_HUMAN	Glia-activating factor	8321227	Molecular cloning of a novel cytokine cDNA encoding the ninth member of the fibroblast growth factor family, which has a unique secretion property.

O42601	S17B1_XENLA	Transcription factor Sox-17-beta.1	10549281	Regulation of Wnt signaling by Sox proteins: XSox17 alpha/beta and XSox3 physically interact with beta-catenin.

Q10424	ZIP1_SCHPO	Transcription factor zip1	15660136	SCF(Pof1)-ubiquitin and its target Zip1 transcription factor mediate cadmium response in fission yeast.

Q9NXZ2	DDX43_HUMAN	Probable ATP-dependent RNA helicase DDX43	10919659	Identification on a human sarcoma of two new genes with tumor- specific expression.

P97352	S10AD_MOUSE	Protein S100-A13	19233122	Protein folding does not prevent the nonclassical export of FGF1 and S100A13.

P25441	RPC4_YEAST	DNA-directed RNA polymerase III subunit RPC4	1406624	RPC53 encodes a subunit of Saccharomyces cerevisiae RNA polymerase C (III) whose inactivation leads to a predominantly G1 arrest.

P84211	BOML2_BOMVA	Bombesin-like peptide 2	15134346	Skin secretion of the toad Bombina variegata contains multiple insulin-releasing peptides including bombesin and entirely novel insulinotropic structures.

Q9H210	OR2D2_HUMAN	Olfactory receptor 2D2	9787077	Organization and evolution of olfactory receptor genes on human chromosome 11.

Q91ZR5	CTSR1_MOUSE	Cation channel sperm-associated protein 1	17174296	Contributions of extracellular and intracellular Ca2+ to regulation of sperm motility: release of intracellular stores can hyperactivate CatSper1 and CatSper2 null sperm.

Q16849	PTPRN_HUMAN	Receptor-type tyrosine-protein phosphatase-like N	8024693	Molecular cloning and identification of a receptor-type protein tyrosine phosphatase, IA-2, from human insulinoma.

P81517	LECA_CRAFL	Lectin alpha chain	10082964	Molecular characterization and crystallization of Diocleinae lectins.

P40818	UBP8_HUMAN	Ubiquitin carboxyl-terminal hydrolase 8	9628861	UBPY: a growth-regulated human ubiquitin isopeptidase.

P33609	DPOLA_MOUSE	DNA polymerase alpha catalytic subunit	8125989	Identification of a point mutation in the cDNA of the catalytic subunit of DNA polymerase alpha from a temperature-sensitive mouse FM3A cell line.

Q9R0Y5	KAD1_MOUSE	Adenylate kinase isoenzyme 1	10557075	wt p53 dependent expression of a membrane-associated isoform of adenylate kinase.

P15732	UBC5_YEAST	Ubiquitin-conjugating enzyme E2-16 kDa	2154373	Ubiquitin-conjugating enzymes UBC4 and UBC5 mediate selective degradation of short-lived and abnormal proteins.

Q10173	NUF2_SCHPO	Kinetochore protein nuf2	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q08298	RD22_ARATH	Dehydration-responsive protein RD22	8479424	The plant hormone abscisic acid mediates the drought-induced expression but not the seed-specific expression of rd22, a gene responsive to dehydration stress in Arabidopsis thaliana.

P63016	PAX6_RAT	Paired box protein Pax-6	11880342	Pax6 regulates specification of ventral neurone subtypes in the hindbrain by establishing progenitor domains.

Q92794	MYST3_HUMAN	Histone acetyltransferase MYST3	18794358	Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexes.

P39549	YAJ9_YEAST	DUP240 protein YAR029W	12101299	Functional analysis of the Saccharomyces cerevisiae DUP240 multigene family reveals membrane-associated proteins that are not essential for cell viability.

Q90Z12	HES4A_XENLA	Transcription factor HES-4-A	18721802	Hairy2-Id3 interactions play an essential role in Xenopus neural crest progenitor specification.

Q96PD4	IL17F_HUMAN	Interleukin-17F	11574464	IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor binding.

P83931	PVK3_RHYMA	Periviscerokinin-3	10849006	Identification of novel periviscerokinins from single neurohaemal release sites in insects. MS/MS fragmentation complemented by Edman degradation.

O75445	USH2A_HUMAN	Usherin	14676276	A domain-specific usherin/collagen IV interaction may be required for stable integration into the basement membrane superstructure.

P46587	HSP72_CANAL	Heat shock protein SSA2	8757872	Evidence for presence in the cell wall of Candida albicans of a protein related to the hsp70 family.

Q93380	UNC93_CAEEL	Putative potassium channel regulatory protein unc-93	14534247	sup-9, sup-10, and unc-93 may encode components of a two-pore K+ channel that coordinates muscle contraction in Caenorhabditis elegans.

Q08962	NIP7_YEAST	60S ribosome subunit biogenesis protein NIP7	9891085	Nip7p interacts with Nop8p, an essential nucleolar protein required for 60S ribosome biogenesis, and the exosome subunit Rrp43p.

Q9SQI2	GIGAN_ARATH	Protein GIGANTEA	15155885	SPINDLY and GIGANTEA interact and act in Arabidopsis thaliana pathways involved in light responses, flowering, and rhythms in cotyledon movements.

Q39024	MPK4_ARATH	Mitogen-activated protein kinase 4	20215588	Arabidopsis homologs of nucleus- and phragmoplast-localized kinase 2 and 3 and mitogen-activated protein kinase 4 are essential for microtubule organization.

P56705	WNT4_HUMAN	Protein Wnt-4	11283799	Up-regulation of wnt-4 signaling and dosage-sensitive sex reversal in humans.

Q14416	GRM2_HUMAN	Metabotropic glutamate receptor 2	7620613	Molecular cloning, functional expression and pharmacological characterization of the human metabotropic glutamate receptor type 2.

Q62968	SCNAA_RAT	Sodium channel protein type 10 subunit alpha	12591166	Sensory neuron proteins interact with the intracellular domains of sodium channel NaV1.8.

Q7TQB9	TR143_MOUSE	Taste receptor type 2 member 143	12734386	Evolutionary relationships of the Tas2r receptor gene families in mouse and human.

Q60860	LTC4S_MOUSE	Leukotriene C4 synthase	8706658	Molecular cloning, expression and characterization of mouse leukotriene C4 synthase.

P22756	GRIK1_RAT	Glutamate receptor, ionotropic kainate 1	1977421	Cloning of a novel glutamate receptor subunit, GluR5: expression in the nervous system during development.

Q38942	RAE1L_ARATH	Rae1-like protein At1g80670	18223036	Characterization of Arabidopsis and rice DWD proteins and their roles as substrate receptors for CUL4-RING E3 ubiquitin ligases.

P63005	LIS1_MOUSE	Platelet-activating factor acetylhydrolase IB subunit alpha	11344260	Targeted mutagenesis of Lis1 disrupts cortical development and LIS1 homodimerization.

Q13451	FKBP5_HUMAN	Peptidyl-prolyl cis-trans isomerase FKBP5	9001212	Molecular cloning of human FKBP51 and comparisons of immunophilin interactions with Hsp90 and progesterone receptor.

Q61006	MUSK_MOUSE	Muscle, skeletal receptor tyrosine-protein kinase	7624144	Cloning and developmental expression of Nsk2, a novel receptor tyrosine kinase implicated in skeletal myogenesis.

P11233	RALA_HUMAN	Ras-related protein Ral-A	17875936	Geranylgeranyltransferase I inhibitors target RalB to inhibit anchorage-dependent growth and induce apoptosis and RalA to inhibit anchorage-independent growth.

Q9ET47	ESPN_MOUSE	Espin	15190118	Espins are multifunctional actin cytoskeletal regulatory proteins in the microvilli of chemosensory and mechanosensory cells.

Q810W9	WHRN_RAT	Whirlin	12641734	CIP98, a novel PDZ domain protein, is expressed in the central nervous system and interacts with calmodulin-dependent serine kinase.

Q9W1W9	PAP21_DROME	PAP21-like protein	14550529	Modifiers of muscle and heart cell fate specification identified by gain-of-function screen in Drosophila.

Q24323	SEM2A_DROME	Semaphorin-2A	8269517	The semaphorin genes encode a family of transmembrane and secreted growth cone guidance molecules.

O43157	PLXB1_HUMAN	Plexin-B1	10520995	Plexins are a large family of receptors for transmembrane, secreted and GPI-anchored semaphorins in vertebrates.

Q40062	IDS3_HORVU	2'-deoxymugineic-acid 2'-dioxygenase	11346963	In vivo evidence that Ids3 from Hordeum vulgare encodes a dioxygenase that converts 2'-deoxymugineic acid to mugineic acid in transgenic rice.

O15816	MYBB_DICDI	Myb-like protein B	9620859	A novel Myb homolog initiates Dictyostelium development by induction of adenylyl cyclase expression.

Q96EP1	CHFR_HUMAN	E3 ubiquitin-protein ligase CHFR	19182791	Chfr is linked to tumour metastasis through the downregulation of HDAC1.

Q9JJW6	REFP2_MOUSE	RNA and export factor-binding protein 2	10786854	REF, an evolutionarily conserved family of hnRNP-like proteins, interacts with TAP/Mex67p and participates in mRNA nuclear export.

Q9USX7	PPK22_SCHPO	Serine/threonine-protein kinase ppk22	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9P0W5	SCHI1_HUMAN	Schwannomin-interacting protein 1	10669747	Cloning and characterization of SCHIP-1, a novel protein interacting specifically with spliced isoforms and naturally occurring mutant NF2 proteins.

P54725	RD23A_HUMAN	UV excision repair protein RAD23 homolog A	8168482	Purification and cloning of a nucleotide excision repair complex involving the Xeroderma pigmentosum group C protein and a human homologue of yeast RAD23.

Q9NNX6	CD209_HUMAN	CD209 antigen	1518869	Sequence and expression of a membrane-associated C-type lectin that exhibits CD4-independent binding of human immunodeficiency virus envelope glycoprotein gp 120.

Q62371	DDR2_MOUSE	Discoidin domain-containing receptor 2	11723120	Discoidin domain receptor 2 regulates fibroblast proliferation and migration through the extracellular matrix in association with transcriptional activation of matrix metalloproteinase-2.

Q17391	CUL3_CAEEL	Cullin-3	15988528	The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae.

Q03944	VPS64_YEAST	Vacuolar protein sorting-associated protein 64	14562095	Global analysis of protein localization in budding yeast.

Q5U5M8	BL1S3_MOUSE	Biogenesis of lysosome-related organelles complex 1 subunit 3	15102850	Identification of snapin and three novel proteins (BLOS1, BLOS2, and BLOS3/reduced pigmentation) as subunits of biogenesis of lysosome- related organelles complex-1 (BLOC-1).

Q9NS23	RASF1_HUMAN	Ras association domain-containing protein 1	11857081	The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore1.

Q8R054	SRPX2_MOUSE	Sushi repeat-containing protein SRPX2	19667118	Sushi repeat protein X-linked 2, a novel mediator of angiogenesis.

P29017	CD1C_HUMAN	T-cell surface glycoprotein CD1c	2701945	Expression of cDNA clones encoding the thymocyte antigens CD1a, b, c demonstrates a hierarchy of exclusion in fibroblasts.

P47743	GRM8_MOUSE	Metabotropic glutamate receptor 8	7722646	A novel metabotropic glutamate receptor expressed in the retina and olfactory bulb.

Q91WM1	STRBP_MOUSE	Spermatid perinuclear RNA-binding protein	7744952	Spnr, a murine RNA binding protein that is localized to cytoplasmic microtubules.

Q13616	CUL1_HUMAN	Cullin-1	8681378	cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family.

P0AFS3	FOLM_ECOLI	Dihydrofolate reductase folM	14617668	FolM, a new chromosomally encoded dihydrofolate reductase in Escherichia coli.

Q967F4	HMR1_CAEEL	Cadherin-related hmr-1	9531567	A putative catenin-cadherin system mediates morphogenesis of the Caenorhabditis elegans embryo.

Q60994	ADIPO_MOUSE	Adiponectin	7592907	A novel serum protein similar to C1q, produced exclusively in adipocytes.

O95402	MED26_HUMAN	Mediator of RNA polymerase II transcription subunit 26	15989967	MED1/TRAP220 exists predominantly in a TRAP/Mediator subpopulation enriched in RNA polymerase II and is required for ER-mediated transcription.

P15308	B4_XENLA	Protein B4	15928086	Nucleosome assembly protein-1 is a linker histone chaperone in Xenopus eggs.

P39997	NPP2_YEAST	Ectonucleotide pyrophosphatase/phosphodiesterase 2	16278456	Pho5p and newly identified nucleotide pyrophosphatases/ phosphodiesterases regulate extracellular nucleotide phosphate metabolism in Saccharomyces cerevisiae.

Q1MTQ9	NIP7_SCHPO	60S ribosome subunit biogenesis protein nip7	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q02100	SKO1_YEAST	CRE-binding bZIP protein SKO1	1437546	Yeast SKO1 gene encodes a bZIP protein that binds to the CRE motif and acts as a repressor of transcription.

Q54HL0	COPG_DICDI	Coatomer subunit gamma	16512674	Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches.

Q9ZWJ9	ARR2_ARATH	Two-component response regulator ARR2	11135105	Arabidopsis ARR1 and ARR2 response regulators operate as transcriptional activators.

Q9ZN78	AFRP_STRGR	A-factor receptor protein	10540289	The A-factor regulatory cascade leading to streptomycin biosynthesis in Streptomyces griseus: identification of a target gene of the A- factor receptor.

Q7Z7K6	CENPV_HUMAN	Centromere protein V	18772885	CENP-V is required for centromere organization, chromosome alignment and cytokinesis.

Q53079	PSB1_RHOER	Proteasome subunit beta 1	16843899	Proteasome assembly triggers a switch required for active-site maturation.

P0AGC5	MLTF_ECOLI	Membrane-bound lytic murein transglycosylase F	18234673	The C-terminal domain of Escherichia coli YfhD functions as a lytic transglycosylase.

Q9LNF2	PMEI1_ARATH	Pectinesterase inhibitor 1	14675772	Identification of pollen-expressed pectin methylesterase inhibitors in Arabidopsis.

P31142	THTM_ECOLI	3-mercaptopyruvate sulfurtransferase	11445076	Properties of the Escherichia coli rhodanese-like protein SseA: contribution of the active-site residue Ser240 to sulfur donor recognition.

O94443	YFE9_SCHPO	Uncharacterized exonuclease C637.09	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q5ARN5	PGLX2_EMENI	Exopolygalacturonase X-2	16844780	Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

Q9NI63	PMYT1_DROME	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	12072468	Ectopic expression of the Drosophila Cdk1 inhibitory kinases, Wee1 and Myt1, interferes with the second mitotic wave and disrupts pattern formation during eye development.

Q08747	UAF30_YEAST	Upstream activation factor subunit UAF30	11500378	Transcription of chromosomal rRNA genes by both RNA polymerase I and II in yeast uaf30 mutants lacking the 30 kDa subunit of transcription factor UAF.

P52294	IMA1_HUMAN	Importin subunit alpha-1	8052633	RAG-1 interacts with the repeated amino acid motif of the human homologue of the yeast protein SRP1.

Q01213	DTDH_MUCMU	4-dihydromethyl-trisporate dehydrogenase	8828234	4-dihydromethyltrisporate dehydrogenase from Mucor mucedo, an enzyme of the sexual hormone pathway: purification, and cloning of the corresponding gene.

Q9HBM1	SPC25_HUMAN	Kinetochore protein Spc25	14699129	Identification of two novel components of the human NDC80 kinetochore complex.

P28562	DUS1_HUMAN	Dual specificity protein phosphatase 1	1406996	Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase.

Q78IQ7	S39A4_MOUSE	Zinc transporter ZIP4	12801924	The acrodermatitis enteropathica gene ZIP4 encodes a tissue-specific, zinc-regulated zinc transporter in mice.

P42656	RAD24_SCHPO	DNA damage checkpoint protein rad24	8036497	14-3-3 protein homologs required for the DNA damage checkpoint in fission yeast.

Q9LF10	CRS1_ARATH	Chloroplastic group IIA intron splicing facilitator CRS1, chloroplastic	17071648	Arabidopsis orthologs of maize chloroplast splicing factors promote splicing of orthologous and species-specific group II introns.

Q13257	MD2L1_HUMAN	Mitotic spindle assembly checkpoint protein MAD2A	11804586	The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20.

O59866	OSTB_SCHPO	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9FR95	PEN1_ARATH	Arabidiol synthase	16774269	A new triterpene synthase from Arabidopsis thaliana produces a tricyclic triterpene with two hydroxyl groups.

Q63302	TFEC_RAT	Transcription factor EC	8336698	TFEC, a basic helix-loop-helix protein, forms heterodimers with TFE3 and inhibits TFE3-dependent transcription activation.

P63014	PRRX1_RAT	Paired mesoderm homeobox protein 1	8749718	rHox: a homeobox gene expressed in osteoblastic cells.

Q07092	COGA1_HUMAN	Collagen alpha-1(XVI) chain	16754661	Collagen XVI harbors an integrin alpha1 beta1 recognition site in its C-terminal domains.

P62166	NCS1_HUMAN	Neuronal calcium sensor 1	11092894	Immunocytochemical localization and crystal structure of human frequenin (neuronal calcium sensor 1).

Q01968	OCRL_HUMAN	Inositol polyphosphate 5-phosphatase OCRL-1	1321346	The Lowe's oculocerebrorenal syndrome gene encodes a protein highly homologous to inositol polyphosphate-5-phosphatase.

Q02936	HH_DROME	Protein hedgehog	8166882	Structure and expression of hedgehog, a Drosophila segment-polarity gene required for cell-cell communication.

O81346	C79B2_ARATH	Tryptophan N-hydroxylase 1	10681464	Arabidopsis cytochrome P450s that catalyze the first step of tryptophan-dependent indole-3-acetic acid biosynthesis.

O94717	YCF5_SCHPO	Uncharacterized protein C1393.05	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q9LM02	SMT1_ARATH	Cycloartenol-C-24-methyltransferase	10852933	Sterol methyltransferase 1 controls the level of cholesterol in plants.

P98170	XIAP_HUMAN	Baculoviral IAP repeat-containing protein 4	8654366	A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors.

O13453	PMP1_SCHPO	Tyrosine-protein phosphatase pmp1	9427748	pmp1+, a suppressor of calcineurin deficiency, encodes a novel MAP kinase phosphatase in fission yeast.

Q9NR83	S2A4R_HUMAN	SLC2A4 regulator	10825161	Identification of a 30-base pair regulatory element and novel DNA binding protein that regulates the human GLUT4 promoter in transgenic mice.

O94740	CDC37_SCHPO	Hsp90 co-chaperone Cdc37	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q6VMQ6	MCAF1_HUMAN	Activating transcription factor 7-interacting protein 1	12665582	MCAF mediates MBD1-dependent transcriptional repression.

Q9R1R0	LHX6_MOUSE	LIM/homeobox protein Lhx6	18339674	NKX2.1 specifies cortical interneuron fate by activating Lhx6.

Q9ULV8	CBLC_HUMAN	Signal transduction protein CBL-C	10362357	cbl-3: a new mammalian cbl family protein.

Q6A2H4	IL10_CHICK	Interleukin-10	15294985	Cloning and characterization of chicken IL-10 and its role in the immune response to Eimeria maxima.

Q63199	TNR6_RAT	Tumor necrosis factor receptor superfamily member 6	7507668	A variant mRNA species encoding a truncated form of Fas antigen in the rat liver.

Q92611	EDEM1_HUMAN	ER degradation-enhancing alpha-mannosidase-like 1	16449189	Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation.

O74453	SKB15_SCHPO	Shk1 kinase-binding protein 15	11389855	Genetic and molecular characterization of Skb15, a highly conserved inhibitor of the fission yeast PAK, Shk1.

O44326	HMP2_CAEEL	Protein humpback-2	11560894	The divergent Caenorhabditis elegans beta-catenin proteins BAR-1, WRM-1 and HMP-2 make distinct protein interactions but retain functional redundancy in vivo.

O14732	IMPA2_HUMAN	Inositol monophosphatase 2	9322233	A novel human myo-inositol monophosphatase gene, IMP.18p, maps to a susceptibility region for bipolar disorder.

P46674	SAC3_YEAST	Nuclear mRNA export protein SAC3	14718168	Sus1, a functional component of the SAGA histone acetylase complex and the nuclear pore-associated mRNA export machinery.

P77488	DXS_ECOLI	1-deoxy-D-xylulose-5-phosphate synthase	9482846	Cloning and characterization of a gene from Escherichia coli encoding a transketolase-like enzyme that catalyzes the synthesis of D-1- deoxyxylulose 5-phosphate, a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis.

Q01882	RAG2_ORYSJ	Seed allergenic protein RAG2	7669811	Classification of rice allergenic protein cDNAs belonging to the alpha-amylase/trypsin inhibitor gene family.

P33887	IF2G_RABIT	Eukaryotic translation initiation factor 2 subunit 3	1911855	Amino acid sequence analysis of the beta- and gamma-subunits of eukaryotic initiation factor eIF-2. Identification of regions interacting with GTP.

Q3UZ18	NARG2_MOUSE	NMDA receptor-regulated protein 2	15606750	NARG2 encodes a novel nuclear protein with (S/T)PXX motifs that is expressed during development.

P04808	REL1_HUMAN	Prorelaxin H1	6298628	Structure of a genomic clone encoding biologically active human relaxin.

P01850	TRBC1_HUMAN	T-cell receptor beta-1 chain C region	6336315	A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains.

P43144	ACHA9_RAT	Neuronal acetylcholine receptor subunit alpha-9	7954834	Alpha 9: an acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells.

Q9UBV2	SE1L1_HUMAN	Protein sel-1 homolog 1	18502753	Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiP.

Q9Y3C4	TPRKB_HUMAN	TP53RK-binding protein	12659830	Identification of CGI-121, a novel PRPK (p53-related protein kinase)- binding protein.

Q04800	FRP1_SCHPO	Ferric reductase transmembrane component 1	8321236	The fission yeast ferric reductase gene frp1+ is required for ferric iron uptake and encodes a protein that is homologous to the gp91-phox subunit of the human NADPH phagocyte oxidoreductase.

Q9P802	MIS18_SCHPO	Kinetochore protein mis18	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q99439	CNN2_HUMAN	Calponin-2	8889829	Molecular cloning and characterization of human non-smooth muscle calponin.

Q9UKT4	FBX5_HUMAN	F-box only protein 5	12791267	Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase.

Q8BUX5	RHBG_MOUSE	Ammonium transporter Rh type B	16131648	Characterization of ammonia transport by the kidney Rh glycoproteins RhBG and RhCG.

Q64364	CD2A2_MOUSE	Cyclin-dependent kinase inhibitor 2A, isoform 3	15105443	p19ARF determines the balance between normal cell proliferation rate and apoptosis during mammary gland development.

Q9P7Y9	SIN1_SCHPO	Stress-activated map kinase-interacting protein 1	10428959	Sin1: an evolutionarily conserved component of the eukaryotic SAPK pathway.

P87157	YB0G_SCHPO	Probable ADP-ribosylation factor-binding protein C25H2.16c	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q92930	RAB8B_HUMAN	Ras-related protein Rab-8B	9030196	RAB GTPases expressed in human melanoma cells.

Q06710	PAX8_HUMAN	Paired box protein Pax-8	9590296	PAX8 mutations associated with congenital hypothyroidism caused by thyroid dysgenesis.

O94421	SNF22_SCHPO	SWI/SNF chromatin-remodeling complex subunit snf22	14988732	Roles of histone acetylation and chromatin remodeling factor in a meiotic recombination hotspot.

O01326	RNC_CAEEL	Ribonuclease 3	15531879	Processing of primary microRNAs by the Microprocessor complex.

O75934	SPF27_HUMAN	Pre-mRNA-splicing factor SPF27	9731529	Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex.

P01446	CX3_NAJKA	Cytotoxin 3	15128311	The first representative of glycosylated three-fingered toxins. Cytotoxin from the Naja kaouthia cobra venom.

P11086	PNMT_HUMAN	Phenylethanolamine N-methyltransferase	2835776	Transgenic mice express the human phenylethanolamine N- methyltransferase gene in adrenal medulla and retina.

Q969S9	RRF2M_HUMAN	Ribosome-releasing factor 2, mitochondrial	19716793	EF-G2mt is an exclusive recycling factor in mammalian mitochondrial protein synthesis.

O60117	YH73_SCHPO	Uncharacterized RING finger protein C16G5.03	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q1J1N6	DDRB_DEIGD	Single-stranded DNA-binding protein DdrB	20129942	The structure of DdrB from Deinococcus: a new fold for single- stranded DNA binding proteins.

Q23639	CUL5_CAEEL	Cullin-5	17184777	C. elegans RBX-2-CUL-5- and RBX-1-CUL-2-based complexes are redundant for oogenesis and activation of the MAP kinase MPK-1.

Q27601	PUR1_DROME	Amidophosphoribosyltransferase	8150282	Molecular and genetic analyses of Drosophila Prat, which encodes the first enzyme of de novo purine biosynthesis.

P35505	FAAA_MOUSE	Fumarylacetoacetase	11209059	Point mutations in the murine fumarylacetoacetate hydrolase gene: animal models for the human genetic disorder hereditary tyrosinemia type 1.

P97784	CRY1_MOUSE	Cryptochrome-1	17462724	Circadian mutant Overtime reveals F-box protein FBXL3 regulation of cryptochrome and period gene expression.

Q9NZC4	EHF_HUMAN	ETS homologous factor	10527851	Human chromosomal localization, tissue/tumor expression, and regulatory function of the ets family gene EHF.

P43605	ECO1_YEAST	N-acetyltransferase ECO1	11864574	Eco1 is a novel acetyltransferase that can acetylate proteins involved in cohesion.

P21865	KDPD_ECOLI	Sensor protein kdpD	1532388	KdpD and KdpE, proteins that control expression of the kdpABC operon, are members of the two-component sensor-effector class of regulators.

P51617	IRAK1_HUMAN	Interleukin-1 receptor-associated kinase 1	12860405	Characterization of Pellino2, a substrate of IRAK1 and IRAK4.

Q62187	TTF1_MOUSE	Transcription termination factor 1	7720715	Different domains of the murine RNA polymerase I-specific termination factor mTTF-I serve distinct functions in transcription termination.

P13535	MYH8_HUMAN	Myosin-8	2715179	Molecular genetic characterization of a developmentally regulated human perinatal myosin heavy chain.

Q9QZS0	CO4A3_MOUSE	Collagen alpha-3(IV) chain	16877525	Tumor-specific expression of the RGD-alpha3(IV)NC1 domain suppresses endothelial tube formation and tumor growth in mice.

Q6PJW8	CNST_HUMAN	Consortin	19864490	Consortin, a trans-Golgi network cargo receptor for the plasma membrane targeting and recycling of connexins.

O04663	IF4E2_ARATH	Eukaryotic translation initiation factor 4E-2	12123581	Loss-of-susceptibility mutants of Arabidopsis thaliana reveal an essential role for eIF(iso)4E during potyvirus infection.

Q4VYS1	FOXP2_XENLA	Forkhead box protein P2	16609867	The FoxP subclass in Xenopus laevis development.

Q91ZR5	CTSR1_MOUSE	Cation channel sperm-associated protein 1	19516020	A novel, single, transmembrane protein CATSPERG is associated with CATSPER1 channel protein.

Q9UK08	GBG8_HUMAN	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8	10819326	Genomic characterization of the human heterotrimeric G protein alpha, beta, and gamma subunit genes.

P62024	PHAR1_RAT	Phosphatase and actin regulator 1	15107502	Phactrs 1-4: a family of protein phosphatase 1 and actin regulatory proteins.

P81917	OR43A_DROME	Odorant receptor 43a	10069338	A novel family of divergent seven-transmembrane proteins: candidate odorant receptors in Drosophila.

Q800K6	TOB1A_XENLA	DNA topoisomerase 2-binding protein 1-A	12743046	Xenopus Cut5 is essential for a CDK-dependent process in the initiation of DNA replication.

Q96GD3	SCMH1_HUMAN	Polycomb protein SCMH1	10524249	The human homolog of Sex comb on midleg (SCMH1) maps to chromosome 1p34.

Q62141	SIN3B_MOUSE	Paired amphipathic helix protein Sin3b	7889570	Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3.

O94150	RT09_CANAL	40S ribosomal protein S9, mitochondrial	10029992	Over-expression of Candida albicans mitochondrial ribosomal protein S9 (MrpS9p) disturbs mitochondrial function in Saccharomyces cerevisiae.

Q07889	SOS1_HUMAN	Son of sevenless homolog 1	8493579	Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2.

P45432	CSN1_ARATH	COP9 signalosome complex subunit 1	8130643	A FUSCA gene of Arabidopsis encodes a novel protein essential for plant development.

P22270	OAR_DROME	Tyramine/octopamine receptor	10713442	A tyramine receptor gene mutation causes a defective olfactory behavior in Drosophila melanogaster.

Q8T7K0	ALIX_DICDI	ALG-2 interacting protein X	15708561	Dd-Alix, a conserved endosome-associated protein, controls Dictyostelium development.

P26769	ADCY2_RAT	Adenylate cyclase type 2	1719547	Molecular cloning and characterization of a Ca2+/calmodulin- insensitive adenylyl cyclase from rat brain.

P05067	A4_HUMAN	Amyloid beta A4 protein	8887653	The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein.

P27708	PYR1_HUMAN	CAD protein	8619816	Molecular cloning of a human cDNA encoding a trifunctional enzyme of carbamoyl-phosphate synthetase-aspartate transcarbamoylase- dihydroorotase in de Novo pyrimidine synthesis.

P33339	TFC4_YEAST	Transcription factor tau 131 kDa subunit	8387209	The TFIIIB-assembling subunit of yeast transcription factor TFIIIC has both tetratricopeptide repeats and basic helix-loop-helix motifs.

Q09161	NCBP1_HUMAN	Nuclear cap-binding protein subunit 1	19648179	A new MIF4G domain-containing protein, CTIF, directs nuclear cap- binding protein CBP80/20-dependent translation.

P17164	FUCO_RAT	Tissue alpha-L-fucosidase	2482732	Isolation and sequence analysis of a cDNA encoding rat liver alpha-L- fucosidase.

Q91Z92	B3GT6_MOUSE	Beta-1,3-galactosyltransferase 6	11551958	Biosynthesis of the linkage region of glycosaminoglycans: cloning and activity of galactosyltransferase II, the sixth member of the beta 1,3-galactosyltransferase family (beta 3GalT6).

Q9D856	S39A5_MOUSE	Zinc transporter ZIP5	15322118	The mammalian Zip5 protein is a zinc transporter that localizes to the basolateral surface of polarized cells.

O13790	CUL1_SCHPO	Cullin-1	17016471	Repression of ergosterol level during oxidative stress by fission yeast F-box protein Pof14 independently of SCF.

Q9WV93	HEY1_MOUSE	Hairy/enhancer-of-split related with YRPW motif protein 1	11486044	HERP, a new primary target of Notch regulated by ligand binding.

P38257	MMS4_YEAST	Crossover junction endonuclease MMS4	9604884	Mms4, a putative transcriptional (co)activator, protects Saccharomyces cerevisiae cells from endogenous and environmental DNA damage.

Q05942	RSA3_YEAST	Ribosome assembly protein 3	15126390	The putative RNA helicase Dbp6p functionally interacts with Rpl3p, Nop8p and the novel trans-acting Factor Rsa3p during biogenesis of 60S ribosomal subunits in Saccharomyces cerevisiae.

P41240	CSK_HUMAN	Tyrosine-protein kinase CSK	1945408	CYL encodes a putative cytoplasmic tyrosine kinase lacking the conserved tyrosine autophosphorylation site (Y416src).

P55809	SCOT1_HUMAN	Succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial	8751852	Succinyl CoA:3-oxoacid CoA transferase (SCOT): human cDNA cloning, human chromosomal mapping to 5p13, and mutation detection in a SCOT- deficient patient.

P25355	CTR86_YEAST	Copper transport protein 86	14562095	Global analysis of protein localization in budding yeast.

Q02199	NUP49_YEAST	Nucleoporin NUP49/NSP49	8524308	Yeast nucleoporin mutants are defective in pre-tRNA splicing.

Q9NGP5	ABCG2_DICDI	ABC transporter G family member 2	11719559	ABC transporters required for endocytosis and endosomal pH regulation in Dictyostelium.

O74955	TSNAX_SCHPO	Translin-associated protein X homolog	16823372	ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Q12286	SUT2_YEAST	Sterol uptake protein 2	11248676	SUT1 is a putative Zn[II]2Cys6-transcription factor whose upregulation enhances both sterol uptake and synthesis in aerobically growing Saccharomyces cerevisiae cells.