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Fig 1.

Flow chart of NHANES cycles 2003–2004 to 2015–2016 full sample to final analytic sample.

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Table 1.

Characteristics of 5101 U.S. adults aged 18–64 years old, NHANES 2003–2004 to 2015–2016.

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Fig 2.

Sex-specific prevalence of cancer risk groups and frequency of HPV subtypes according to cancer risk groups.

Panel B) Individuals with multiple infections of a specific cancer group appear as multiple counts if they have multiple HPV infections. For example, if an individual has an HPV type 6 and 11 infection, they will appear as a count for both bars 6 and 11. HPV testing was done through vaginal swabs for females (18-59y, 2003–2004 to 2015–2016) and penile swabs for males (18-59y, 2013–2014 to 2015–16) using Roche Linear Array Assays, and oral swabs for both males and females (18-69y, 2009–2010 to 2015–2016).

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Fig 3.

Kaplan-Meier curves across cancer risk groups, stratified by sex.

Survival differences across cancer risk groups was assessed by global chi-squared analysis.

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Table 2.

Odds of MetS across cancer risk groups, stratified by sex.

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Table 3.

Effects of HPV on risk of mortality, stratified by sex.

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Fig 4.

Effects of HPV and MetS on risk of mortality, stratified by sex.

These figures provide results of cox regressions to assess risk of mortality across cross-classified cancer risk groups and MetS in unadjusted and fully adjusted models, across males and females. HR = hazard ratio.

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