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Table 1.

Participants characteristics.

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Table 1 Expand

Table 2.

Group level changes.

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Table 2 Expand

Table 3.

Inter-individual variability at a global level.

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Table 3 Expand

Fig 1.

Individual responses.

Individual change scores (CS) from PRE to 8wk and PRE to 16wk for SED and EX. A) Maximal voluntary contraction (MVC), B) rate of force development (RFD), C) quadriceps cross-sectional area (qCSA), D) type I fibre cross-sectional area (fCSA), E) type II fCSA. Participants are ranked according to their CS, and their responses are categorized as Negative (orange), Neutral (white), or Positive (blue), relative to the typical error (grey zone). Abbreviation: Nm, Newton meter.

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Fig 1 Expand

Fig 2.

Responder classification.

Heatmaps showing ranked responses for each outcome, at PRE to 8wk and PRE to 16wk. Blue and orange lines are used to show Positive (≥ the positive TE) and Negative (≤ the negative TE) responses, with all other responses being Neutral (see Fig 1). Based on integration of responses for each outcome, individuals were classified as Excellent (green), Robust (light green), Trivial (Yellow) and Poor (red) responders.

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Fig 3.

Training progression.

Percent change in 1RM in leg extension, leg press and leg curl for participants categorized as Poor (red), Trivial (yellow), Robust (light green) and Excellent (green) responders at PRE to 16wk. Data are means ± SD with individual data points, and were analysed using two-way mixed-effects model with session number and responder classification as independent factors. Abbreviation: 1RM, 1-repetition maximum.

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Fig 3 Expand

Fig 4.

Baseline levels. Pearson’s correlation between baseline levels and percentage change at PRE to 16 weeks for all participants in EX, in MVC (A), RFD (B), qCSA (C), and type II fCSA (D).

Participants are shown according to their responder classification; Poor (red), Trivial (yellow), Robust (light green) and Excellent (green). Linear correlation line is shown, and slope, R2, and P-values were inserted. Abbreviation: MVC, maximal voluntary contraction; RFD, rate of force development; qCSA, quadriceps cross-sectional area; fCSA, fibre cross-sectional area.

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Fig 4 Expand