Table 1.
Demographics of UK Biobank participants with RA who provided actigraphy data and met eligibility criteria.
Table 2.
Disease characteristics of UK Biobank participants with RA who provided actigraphy data and met eligibility criteria.
Fig 1.
Population average activity profiles for (A) participants with RA, (B) non-RA controls, (C) difference between the two profiles (highlighted by dotted lines and arrows) and (D) differences between profiles for RA and non-RA subgroups who were not working and had morning chronotype; the RA subgroup excludes self-report diagnosis and early disease onset.
MVPA, moderate-to-vigorous physical activity; RA, rheumatoid arthritis.
Fig 2.
Mean relative difference between groups expressed as the ratio of participants with RA to non-RA controls for relevant significant metrics * in the total volume of activity domain.
* Non-significant metrics are not included. ANCOVA, analysis of covariance; ANOVA, analysis of variance; MVPA, moderate-to-vigorous physical activity; RA, rheumatoid arthritis; SD, standard deviation.
Fig 3.
Mean relative difference between groups expressed as the ratio of participants with RA to non-RA controls for relevant significant metrics in the morning activity (morning stiffness), night-time activity (disturbed sleep and restlessness) and fragmentation of activity domains.
ANCOVA, analysis of covariance; ANOVA, analysis of variance; AUC, area under the curve; MVPA, moderate-to-vigorous physical activity; M10, midpoint time of the most-active 10 hours; RA, rheumatoid arthritis; SD, standard deviation.
Fig 4.
Biplot of the PCA showing loadings of variables (colored by domain) on the first three PCs: (A) and (B) presents different orientations of the 3D space defined by the PCs.
MVPA, moderate-to-vigorous physical activity; M10, midpoint time of the most-active 10 hours; PC, principal component; PCA, principal component analysis; SD, standard deviation.