Fig 1.
Cohort entry was defined as a patient’s date of registration with health insurance or April 1, 2012, whichever occurred later. The key date was the initial date of an annual health checkup with > 12 months of continuous subscribership to the health insurance system. The baseline was the 12 months preceding the key date. The observation period was the interval between the key date and (1) the end of the study (September 30, 2020) or (2) the date of withdrawal from the health insurance system, whichever occurred first. NHI, National Health Insurance; LSEMCS, Late-Stage Elderly Medical Care System.
Table 1.
Baseline characteristics of participants.
Fig 2.
Flow diagram of cohort enrolment.
Table 2.
Univariable and multivariable Cox regression analysis of esophageal cancer onset.
Fig 3.
Cumulative incidence of esophageal cancer by MCV quartile category considering death as a competing risk.
Q, quartile.
Fig 4.
Conditional inference tree for predicting esophageal cancer onset with cutoff values for mean corpuscular volume (MCV).
Table 3.
Mean corpuscular volume in participants with alcohol use disorder.