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Fig 1.

Study flow diagram.

Assignment to the CAQ or control arms alternated weekly during the trial period based on the date of screening The participants in the CAQ and control arms that responded to the study survey consistuted the intention-to-treat (ITT) group. The CAQ arm was partitioned into groups of participants who reported reading the CAQ and those who did not report or recall reading the CAQ that were used in a per-protocol (PP) analysis. All participants were followed for adherence to follow-up.

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Fig 2.

Study enrollment and follow-up timeline.

This figure demonstrates the flow through the participation elements from enrollment with randomization, follow-up surveys and adjudication of adherence to follow-up.

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Fig 3.

“Common Questions after your Lung Cancer Screening” (CAQ) handout which was mailed to patients in the intervention arm who underwent LCS.

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Table 1.

Comparison of responders and non-responders (n = 389 eligible patients).

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Table 2.

Survey-respondant characteristics (n = 230).

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Table 3.

Comparison of the primary study outcomes between intention-to-treat groups (n = 230).

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Table 4.

Comparison of the secondary study outcomes between intention-to-treat groups (n = 230).

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Fig 4.

Comparison of answers on 6 understanding and knowledge questions among baseline screening participants between the CAQ arm and control arm.

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Table 5.

Comparison of the primary and secondary study outcomes between intention-to-treat groups, stratified by baseline vs. subsequent LCS exam (n = 230).

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Table 6.

Comparison of the primary and secondary study outcomes between per-protocol groups (n = 230).

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Table 7.

CAQ acceptability and appropriateness (n = 44 subjects who reported reading the CAQ sheet).

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Table 8.

Follow-up adherence rates by groups (n = 386).

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