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Fig 1.

Diagram of the macroeconomic model.

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Table 1.

List of noncommunicable diseases.

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Table 2.

Macroeconomic burden of NMHs over the period 2020–2050.

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Fig 2.

Macroeconomic burden of NMHs by country and year (as a percentage of yearly GDP).

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Table 3.

Macroeconomic burden of leading NMHs: Total GDP loss (in billions, 2022 international $)i.

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Fig 3.

Macroeconomic burden of NMHs for the whole South American region over the period 2020–2050 across various scenarios.

Baseline scenario = 3% discount rate, disease burden based on median estimates from the 2019 Global Burden of Diseases (GBD) [1], morbidity affects labor force participation, and treatment costs decrease investments in physical capital proportionally to the saving rate. Low disease burden = disease burden based on 2.5 percentile estimates provided by GBD; all other assumptions as in the baseline scenario. High disease burden = burden based on 97.5 percentile estimates provided by GBD; all other assumptions as in the baseline scenario. Larger treatment cost impact scenario = treatment costs reduce physical capital investments by a proportion 50% greater than the saving rate; all other assumptions as in the baseline scenario. No treatment cost impact scenario = treatment costs do not reduce physical capital investments; all other assumptions as in the baseline scenario. No morbidity impact = morbidity does not affect labor force participation; all other assumptions as in the baseline scenario. 1% discount rate scenario = 1% discount rate; all other assumptions as in the baseline scenario. 5% discount rate scenario = 5% discount rate; all other assumptions as in the baseline scenario. The error bars denote 95% confidence intervals.

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