Fig 1.
Heatmap detailing the pairwise correlations between the 10 echocardiographic variables and the two cardiac biomarkers, troponin I and NT-proBNP.
A, atrial maximal transmitral Doppler velocity; EA, E wave to A wave ratio; EF, ejection fraction; IVRT, interventricular relaxation time; IVS, interventricular septum thickness; LA, left atrial diameter; LVEDD, left ventricular end diastolic diameter; LVMI, left ventricular mass index; NTproBNP, N-terminal-pro hormone B-type natriuretic peptide; SV, stoke volume; Trop, Troponin I.
Table 1.
Echocardiographic variables, cardiac biomarkers and traditional risk factors at each age-based assessment.
Table 2.
The associations between incident cardiovascular disease (combined end-point) and the echocardiographic variables, and the two cardiac biomarkers.
Fig 2.
Spline functions for left atrial diameter (upper panel) and left ventricular ejection fraction (lower panel). The hazard ratio is represented by the black solid line and the 95% confidence intervals are represented by the dashed lines. A hazard ratio of 1 is indicated by the red horizontal line. CVD, cardiovascular disease.
Table 3.
Each model’s predictive power for incident cardiovascular disease.
Table 4.
The separate associations that exist for incident myocardial infarction, heart failure and ischemic stroke with the echocardiographic variables and two cardiac biomarkers.